[ { "cls_id": "homologset.agr.MGI:1101358", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q11011-1", "uniprot_id": "PSA_MOUSE", "id": "Q11011-1", "name": "Puromycin-sensitive aminopeptidase", "aln": "---------------------------------------MWLAAAVPSLARRLLLLGPPPPPLLLLLSR--------------------------------------------------------------SSRRRRRLHSLGLAA---------------------------------------------------------------MPEKRPFERLPAEVSPINYSLCLKPDLLDFTFEGKLEAAAQVRQATNQIVMNCADIDIITASYAPEGDEEIHATGFNYQNEDEKVTLSFPSTLQTGT---GTLKIDFVGELNDKMKGFYRSRYTTP-AGEVRYAAVTQFEATDARRAFPCWDEPAIKATFDISLVVPKDRVALSNMNVIDRKPYPDDENLVEVKFARTPVMSTYLVAFVVGEYDFVETRSKDGVCVRVYTPVGKAEQGKFALEVAAKTLPFYKDYFNVPYPLPKIDLIAIADFAAGAMENWGLVTYRETALLIDPKNSCSSSRQWVALVVGHELAHQWFGNLVTMEWWTHLWLNEGFASWIEYLCVDHCFPEYDIWTQFVSADYTRAQELDALDNSHPIEVSVGHPSEVDEIFDAISYSKGASVIRMLHDYIGDKDFKKGMNMYLTKFQQKNAATEDLWESLESASGKPIAAVMNTWTKQMGFPLIYVEAEQVE-DDRVLKLSQKKFCASGPYGGEDCPQWMVPITISTSEDPNQAKLKILMDKPEMSVVLKNVKPDQWVKLNLGTVGFYRTQYSSAMLESLLPGIRDLSLPPVDRLGLQNDLFSLARAGIISTVEVLKVMEAFVNEPNYTVWSDLSCNLGILS--TLLSHTDFYEEIQEFVKDVFSPIGERLGWDPKPGEGHLDALLRGLVLGKLGKAGHKATLEEARRRFKEHVEG-KQILSADLRSPVYLTVLKHGDGATLDIMLKLHKQADMQEEKNRIERVLGATLSPELIQKVLTFALSEEVRPQDTVSVIGGVAGGSKHGRKAAWKFIKDNWEELHNRYQGG-FLISRLIKLSVEGFAVDKMAGEVKAFFESHPAPSAERTIQQCCENILLNAAWLKRDADSIHQYLLQRKTSPPSV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1M9V7-1", "uniprot_id": "F1M9V7_RAT", "id": "F1M9V7-1", "name": "Aminopeptidase", "aln": "---------------------------------------MWLAAAVPSLARRLLLLGSPPPPLLLLLSR--------------------------------------------------------------SSSRRRRLHSLGLAA---------------------------------------------------------------MPEKRPFERLPTEVSPINYSLCLKPDLLDFTFEGKLEAAAQVRQATNQIVMNCADIDIITASYAPEGDEEIHATGFNYQNEDEKVTLSFPSTLQTGT---GTLKIDFVGELNDKMKGFYRSRYTTP-AGEVRYAAVTQFEATDARRAFPCWDEPAIKATFDISLVVPKDRVALSNMNVIDRKPYPDDENLVEVKFARTPVMSTYLVAFVVGEYDFVETRSKDGVCVRVYTPVGKAEQGKFALEVAAKTLPFYKDYFNVPYPLPKIDLIAIADFAAGAMENWGLVTYRETALLIDPKNSCSSSRQWVALVVGHELAHQWFGNLVTMEWWTHLWLNEGFASWIEYLCVDHCFPEYDIWTQFVSADYTRAQELDALDNSHPIEVSVGHPSEVDEIFDAISYSKGASVIRMLHDYIGDKDFKKGMNMYLTKFQQKNAATEDLWESLESASGKPIAAVMNTWTKQMGFPLIYVEAEQVE-DDRVLKLSQKKFCASGPYVGEDCPQWMVPITISTSEDPNQAKLKILMDKPEMSVVLKNVKPDQWVKLNLGTVGFYRTQYSSAMLESLLPGIRDLSLPPVDRLGLQNDLFSLARAGIISTVEVLKVMEAFVNEPNYTVWSDLSCNLGILS--TLLSHTDFYEEIQEFVKDVFSPIGERLGWDPKPGEGHLDALLRGLVLGKLGKAGHKATLEEARRRFKEHVEG-KQILSADLRSPVYLTVLKHGDGTTLDIMLKLHKQADMQEEKNRIERVLGATLSPELIQKVLTFALSEEVRPQDTVSVIGGVAGGSKHGRKAAWKFIKDNWEELYNRYQGG-FLISRLIKLSVEGFAVDKMAGEVKAFFESHPAPSAERTIQQCCENILLNAAWLKRDADSIHQYLLQRKASPPSV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P55786-1", "uniprot_id": "PSA_HUMAN", "id": "P55786-1", "name": "Puromycin-sensitive aminopeptidase", "aln": "---------------------------------------MWLAAAAPSLARRLLFLGPPPPPLLLLVFS--------------------------------------------------------------RSSRRR-LHSLGLAA---------------------------------------------------------------MPEKRPFERLPADVSPINYSLCLKPDLLDFTFEGKLEAAAQVRQATNQIVMNCADIDIITASYAPEGDEEIHATGFNYQNEDEKVTLSFPSTLQTGT---GTLKIDFVGELNDKMKGFYRSKYTTP-SGEVRYAAVTQFEATDARRAFPCWDEPAIKATFDISLVVPKDRVALSNMNVIDRKPYPDDENLVEVKFARTPVMSTYLVAFVVGEYDFVETRSKDGVCVRVYTPVGKAEQGKFALEVAAKTLPFYKDYFNVPYPLPKIDLIAIADFAAGAMENWGLVTYRETALLIDPKNSCSSSRQWVALVVGHELAHQWFGNLVTMEWWTHLWLNEGFASWIEYLCVDHCFPEYDIWTQFVSADYTRAQELDALDNSHPIEVSVGHPSEVDEIFDAISYSKGASVIRMLHDYIGDKDFKKGMNMYLTKFQQKNAATEDLWESLENASGKPIAAVMNTWTKQMGFPLIYVEAEQVE-DDRLLRLSQKKFCAGGSYVGEDCPQWMVPITISTSEDPNQAKLKILMDKPEMNVVLKNVKPDQWVKLNLGTVGFYRTQYSSAMLESLLPGIRDLSLPPVDRLGLQNDLFSLARAGIISTVEVLKVMEAFVNEPNYTVWSDLSCNLGILS--TLLSHTDFYEEIQEFVKDVFSPIGERLGWDPKPGEGHLDALLRGLVLGKLGKAGHKATLEEARRRFKDHVEG-KQILSADLRSPVYLTVLKHGDGTTLDIMLKLHKQADMQEEKNRIERVLGATLLPDLIQKVLTFALSEEVRPQDTVSVIGGVAGGSKHGRKAAWKFIKDNWEELYNRYQGG-FLISRLIKLSVEGFAVDKMAGEVKAFFESHPAPSAERTIQQCCENILLNAAWLKRDAESIHQYLLQRKASPPTV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NSE3-1", "uniprot_id": "A0A8M1NSE3_DANRE", "id": "A0A8M1NSE3-1", "name": "Aminopeptidase", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPERRPFVRLPTDVYPVNYGLRLKPDLVDFTFEGKLEAAVEVTQGTNQIVMNCADIDIITASFVPDGGEEINATGFNYQNEDEKVTLCFPSTLQKGS---GSLKIDFVGELNDKMKGFYRSKYSS--SGEVRYAAVTQFEATDARRAFPCWDEPAIKATFDITLIVPKDRVALSNMNVVDRKPYAEDQSLVEVKFATTPIMSTYLVAFVIGEYDFVESQSSDGVTVRVYTPVGKAEQGKFALEVATKTLPFYKDYFSVPYPLPKIDLIAIADFAAGAMENWGLVTYRETALLIDPKNSCASSRQWVALVVGHELAHQWFGNLVTMEWWTHLWLNEGFASWIEYLCVDHCFPEYDIWTQFVSADYTRALDLDALDNSHPIEVDVGHPSEVDEIFDAISYSKGASVIRMLHNYIGDEDFRKGMNAYLLKFQHKNASTEDLWECLEQASGKPIAAVMNSWTKQMGFPIIVVDQEQHG-SDRVLKISQKKFCASGPRNDEDCPNWMVPISICTSEDPSCTKTKILLDQPETTVNITNVAPDHWIKINPGTVGFYRIQYSSAMLESLLPGIRDLTLLPVDRLGLQNDLFSLARAGMISTVEVLKVMEAFVNEPNYTVWSDLSCNLGVLS--SLLSHTDFHEDIQEFIRDLFTPIGMKLGWDSRTGEGHLDALLRGLVLGKLGKAGHKATLEEARRRFREHVEG-KQILSADLRSPVYLTVLKHGDSTTLDTMLKLHKQADMQEEKNRIERVLGAIPAPDLIQRVLNFALSEEVRPQDTVSVIGGVAGSSKQGRKAAWKFVKDNWEELHNRYQGG-FLISRLIKLTVDGFAIDKMAAEVKSFFESHHAPAAERTVQQCCENILLNAAWLKRDADDIHQYLLQRKTPPV--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IRH1-1", "uniprot_id": "Q8IRH1_DROME", "id": "Q8IRH1-1", "name": "Puromycin-sensitive aminopeptidase", "aln": "MYKNALKGGIRTAKQAWKLKNELGKLNLDLAKANSDFEQHLCEAARYTQSFHFLARNTPRTPLLLLKTTGDNNSSPRIVANYYRTAPVNPPKQQNPKPSGAADKTTSVKHLFRAESGHLNALISSKQFVKVQKQFYRDFSSVSLGAPLKSSDAPLLGDLCSQYRAILAHTSADVIPGQDRHHPGCNYQQIRRAHTQLLSKEQQLEQERKMAQKAKFERLPTNVVPRHYELLLQPNLKEFTFTGKTVVQVNVKEPTTQITLNALDIVLDSVELHFECS-KLKPEKIVYSAENETATLEFAQEIPAETQ--GVLHMSFTGELNDKMKGFYRSKYFGP-NGEERFAGVTQFEATDARRCFPCWDEPAIKATFDITLVVPKDRVALSNMPVIKEDSLPDG--LRRVRFDRTPIMSTYLVAVVVGEYDYVEGKSDDGVLVRVFTPVGKREQGTFALEVATKVLPYYKDYFNIAYPLPKMDLIAISDFSAGAMENWGLVTYRETFVLVDPKNTSLMRKQSIALTVGHEIAHQWFGNLVTMEWWTHLWLNEGYASFVEFLCVHHLFPEYDIWTQFVTDMYTRALELDSLKNSHPIEVPVGHPSEIDEIFDEISYNKGASVIRMLHDYIGEDTFRKGMNLYLTRHQYGNTCTEDLWAALQEASSKNVSDVMTSWTQHKGFPVVSVESEQTSKNQRLLRLKQCKFTADGSQADENC-LWVVPISVSTSKNPTGIAKTFLLDKSSMEVTLDNVDEDDWIKINPGTVGYYRTRYSQEMLEQLMPAVEKMELPPLDRLGLIDDMFAMVQAGHASTADVLALVDSYRNETNYTVWTAITNSLTNLH--ILISHTDLMEDFHRFGRNLYEPVAYRLGWEPRDGENHLDTLLRSLVLTRLVSFRSSDTIEEAKIRFRRHVNG-TELLPADLRTTCYKAVLQDGDEKIFNEMLDLYRATDLHEEQDRISRALGCCGDLKLLRRVIDFAMSSEVRAQDSVFVIVAVAINPK-GRDMAWEFFKENNKQLLERYQGG-FLLSRLIKYLIENFASEERAKEVEEFLQVNQIPGCERTVSQAVETIRLNAAWLQRDREQLAIFLRDDQ------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32454-1", "uniprot_id": "APE2_YEAST", "id": "P32454-1", "name": "Aminopeptidase 2, mitochondrial", "aln": "----MPIVRWLLLKSAVRGSSLIGKAHPCLRSIAAHPRYLSNVYSPPAGVSRSLRINVMWKQSKLTPPR------------------------------------------------------------FVKIMNRRPLFTETSHACAKCQKTS-----------------------------------------------------QLLNKTPNREILPDNVVPLHYDLTVEPDFKTFKFEGSVKIELKINNPA----IDTVTLNTVDTDIHSAKIGDVTSSEIISEEEQQVTTFAFPKGTMSSFKGNAFLDIKFTGILNDNMAGFYRAKYEDKLTGETKYMATTQMEPTDARRAFPCFDEPNLKASFAITLVSDPSLTHLSNMDVKNEYVKDGK---KVTLFNTTPKMSTYLVAFIVAELKYVESKNFR-IPVRVYATPGNEKHGQFAADLTAKTLAFFEKTFGIQYPLPKMDNVAVHEFSAGAMENWGLVTYRVVDLLLDKDNSTLDRIQRVAEVVQHELAHQWFGNLVTMDWWEGLWLNEGFATWMSWYSCNEFQPEWKVWEQYVTDTLQHALSLDSLRSSHPIEVPVKKADEINQIFDAISYSKGASLLRMISKWLGEETFIKGVSQYLNKFKYGNAKTEDLWDALADASGKDVRSVMNIWTKKVGFPVISVSEDGNG---KITFRQNRYLSTADVKPDEDKTIYPVFLALKTKNG---VDSSVVLSERSKTIELE---DPTFFKVNSEQSGIYITSYTDERWAKLG--QQADLLSVEDRVGLVADVKTLSASGYTSTTNFLNLVSKWNNEKSFVVWDQIINSISSMKSTWLFEPKETQDALDNFTKQLISGMTHHLGWEFKSSDSFSTQRLKVTMFGAACAARDADVEKAALKMFTDYCSGNKEAIPALIKPIVFNTVARVGGAENYEKVYKIYLDPISNDEKLAALRSLGRFKEPKLLERTLGYLFDGTVLNQDIYIPMQGMR-AHQEGVEALWNWVKKNWDELVKRLPPGLSMLGSVVTLGTSGFTSMQKIDEIKKFFATKSTKGFDQSLAQSLDTITSKAQWVNRDRDVVNKYLKENGYY----", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P37898-1", "uniprot_id": "AAP1_YEAST", "id": "P37898-1", "name": "Alanine/arginine aminopeptidase", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSREVLPNNVTPLHYDITLEPNFRAFTFEGSLKIDLQINDHS----INSVQINYLEIDFHSARIEGVNAIEVNKNENQQKATLVFPNGTFENLGPSAKLEIIFSGILNDQMAGFYRAKYTDKVTGETKYMATTQMEATDARRAFPCFDEPNLKATFAVTLVSESFLTHLSNMDVRNETIKEGK---KYTTFNTTPKMSTYLVAFIVADLRYVESNNFR-IPVRVYSTPGDEKFGQFAANLAARTLRFFEDTFNIEYPLPKMDMVAVHEFSAGAMENWGLVTYRVIDLLLDIENSSLDRIQRVAEVIQHELAHQWFGNLVTMDWWEGLWLNEGFATWMSWYSCNKFQPEWKVWEQYVTDNLQRALNLDSLRSSHPIEVPVNNADEINQIFDAISYSKGSSLLRMISKWLGEETFIKGVSQYLNKFKYGNAKTGDLWDALADASGKDVCSVMNIWTKRVGFPVLSVKEHKN----KITLTQHRYLSTGDVKEEEDTTIYPILLALKDSTG---IDNTLVLNEKSATFELK---NEEFFKINGDQSGIFITSYSDERWAKLS--KQANLLSVEDRVGLVADAKALSASGYTSTTNFLNLISNWKNEDSFVVWEQIINSLSALKSTWVFEPEDILNALDKFTLDLVLNKLSELGWNIGEDDSFAIQRLKVTLFSAACTSGNEKMQSIAVEMFEEYANGNKQAIPALFKAVVFNTVARLGGENNYEKIFNIYQNPVSSEEKIIALRALGRFEDKELLERTLSYLLDGTVLNQDFYIPMQGIR-VHKKGIERLWAWMQEHWDEIAKRLQPGSPVLGGVLTLGLTNFTSFEALEKISAFYSRKVTKGFDQTLAQALDTIRSKAQWVSRDREIVATYLREHEYDQ---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** :* * :* : ::*:: *.* *. :: : : :: : . : . . . ::: .*: *.. . *.: * * ***:* ****::* ** :: ..**:*.*****.***:*** :**:* ::*: . **** * .. . * ** *******.::.: :** .. : ***::. *. : * ** :::::.* :::. *.: *****:* :*: :*:************* :*:* .*: * :* .: **:***********:** ******:*:::.: . .. **:.:* *:*: :* .**:* .****** * :..*:::*** ***.**:*::**: .::*:. * **:. ** :.: *: * *** .* .**.* : **. **:: ***:: *. . :: .: : : . *: : : ::: . . ..::.: . . : :.*:* * : *:. .* . * **:** * :: :* **.:.* ::. : ** .:.** : .: : ::. : : :..* :: .***: .:.. *: :: . * * : .* .: :.* ::. : :* : *. : : .:: . :*: * ** .*:.:.: : :. * ** : .: : * . * :.:.: .:: :* * ::. ::. .*: : ::. * : . :::: *. :.* :* *:.** : : :* : ", "identical_positions": 220, "similar_positions": 284, "identity": "20.13%" }, { "cls_id": "homologset.agr.MGI:1101759", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4KLY4-1", "uniprot_id": "RING2_RAT", "id": "Q4KLY4-1", "name": "E3 ubiquitin-protein ligase RING2", "aln": "MSQAVQTNGTQPLSKTWELSLYELQRTPQEAITDGLEIVVSPRSLHSELMCPICLDMLKNTMTTKECLHRFCADCIITALRSGNKECPTCRKKLVSKRSLRPDPNFDALISKIYPSRDEYEAHQERVLARINKHNNQQALSHSIEEGLKIQAMNRLQRGKKQQIENGSGAEDNG----------------------------------DSSHCSNASTHSNQEAGPS------------NKRTKTSDDSG-------LELDNNN---------------------------------AAVAIDPVMDGAS--------------------EIELVFRPHPTLMEKD-------DSAQTRYIKTSGNATVDHLSKYLAVRLALEELRSKGESNQMNLDTASEKQYTIYIATASGQFTVS--------ICQ--------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CQJ4-1", "uniprot_id": "RING2_MOUSE", "id": "Q9CQJ4-1", "name": "E3 ubiquitin-protein ligase RING2", "aln": "MSQAVQTNGTQPLSKTWELSLYELQRTPQEAITDGLEIVVSPRSLHSELMCPICLDMLKNTMTTKECLHRFCADCIITALRSGNKECPTCRKKLVSKRSLRPDPNFDALISKIYPSRDEYEAHQERVLARINKHNNQQALSHSIEEGLKIQAMNRLQRGKKQQIENGSGAEDNG----------------------------------DSSHCSNASTHSNQEAGPS------------NKRTKTSDDSG-------LELDNNN---------------------------------AAVAIDPVMDGAS--------------------EIELVFRPHPTLMEKD-------DSAQTRYIKTSGNATVDHLSKYLAVRLALEELRSKGESNQMNLDTASEKQYTIYIATASGQFTVLNGSFSLELVSEKYWKVNKPMELYYAPTKEHK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99496-1", "uniprot_id": "RING2_HUMAN", "id": "Q99496-1", "name": "E3 ubiquitin-protein ligase RING2", "aln": "MSQAVQTNGTQPLSKTWELSLYELQRTPQEAITDGLEIVVSPRSLHSELMCPICLDMLKNTMTTKECLHRFCADCIITALRSGNKECPTCRKKLVSKRSLRPDPNFDALISKIYPSRDEYEAHQERVLARINKHNNQQALSHSIEEGLKIQAMNRLQRGKKQQIENGSGAEDNG----------------------------------DSSHCSNASTHSNQEAGPS------------NKRTKTSDDSG-------LELDNNN---------------------------------AAMAIDPVMDGAS--------------------EIELVFRPHPTLMEKD-------DSAQTRYIKTSGNATVDHLSKYLAVRLALEELRSKGESNQMNLDTASEKQYTIYIATASGQFTVLNGSFSLELVSEKYWKVNKPMELYYAPTKEHK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q803I4-1", "uniprot_id": "RING2_DANRE", "id": "Q803I4-1", "name": "E3 ubiquitin-protein ligase RING2", "aln": "MTQTVQTNGVQPLSKTWELSLYELQRTPQEAITDGLEIAVSPRSLHSELMCPICLDMLKNTMTTKECLHRFCADCIITALRSGNKECPTCRKKLVSKRSLRPDPNFDALISKIYPSRDEYEAHQERVLARISKHNNQQALSHSIEEGLKIQAMNRLQRGKKHQIENGSGAEDNG----------------------------------DSSHCSNASVHSNQEAGPS------------IKRTKTSDDSG-------LDMDNAT---------------------------------ENGGGDIALDGVS--------------------EIELVFRPHPTLMEKE-------DAAQTRYIKTSGNATVDHLSKYLAVRLALEEMRKNGEASPINVEAASEKQYTIYIPTASNQFTVLNGSFSLELVSEKYWKVNKPMELYFAPTKEHK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VB08-1", "uniprot_id": "RING1_DROME", "id": "Q9VB08-1", "name": "E3 ubiquitin-protein ligase RING1", "aln": "-----MTSLDPAPNKTWELSLYELQRKPQEVITDSTEIAVSPRSLHSELMCPICLDMLKKTMTTKECLHRFCSDCIVTALRSGNKECPTCRKKLVSKRSLRADPNFDLLISKIYPSREEYEAIQEKVMAKFNQTQSQQALVNSINEGIKLQSQNRPQRFRTKGGGGGGGGGGNGNGAANVAAPPAPGAPTAVGRNASNQMHVHDTASNDSNSNTNSIDRENRDPGHSGTSAASAITSASNAAPSSSANSGASTSATRMQVDDASNPPSVRSTPSPVPSNSSSSKPKRAMSVLTSERSEESESDSQMDCRTEGDSNIDTEGEGNGELGINDEIELVFKPHPTEMSADNQLIRALKENCVRYIKTTANATVDHLSKYLAMRLTLDLGADLPEACRV-------LNFCIYVAPQPQQLVILNGNQTLHQVNDKFWKVNKPMEMYYSWKKT--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. . .************.***.***. **.********************:************:***:************************.***** *********:**** **:*:*::.: :.**** :**:**:*:*: ** ** :.: .*.*. .** **. :*: :.*::.* * ..:* :** :::*: . * :* : ******:**** *. : . .*****:.************:**:*: . *: : :: **:.. . *:.: : : ", "identical_positions": 167, "similar_positions": 75, "identity": "37.19%" }, { "cls_id": "homologset.agr.MGI:1101760", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZKI9-1", "uniprot_id": "A0A8I5ZKI9_RAT", "id": "A0A8I5ZKI9-1", "name": "", "aln": "-----MAAEEALKTVDHYKTEIERLTKELTETTHEKIQAAEYGLVVLEEKLTLKQQYDELEAEYDGLKQELEQLKEAFGQSFSIHRKVAEDGETREETLLQESASKEAYYLNKILEMQNELKQSRAVVTNVQAENERLSAVVQELKENNEMVELQRIRMKDEIREYKFREARLLQDYTELEEENITLQKLVSTLKQNQVEYEGLKHEIKRFEEETVLLNSQLEDAIRLKEIAEHQLEEALETLKNEREQKNNLRKELSQYISLSD------NHISIS-VEGLKFAEDGSEPNNDDKMNGHLHGPLGKLNGDYR-----APTARKGESLHPVSDLFSELNISEIQKLKQQLIQVEREKAILLANLQESQTQLEHTKGALTEQHERVHRLTEHVNAMRGLQNSKELKAELDCEKGRNSAEEAHDYEVDINGLEILECKYRVAVTEVID-LKAEIKALKEKYNKSVENYTEEKTKYESKIQMYDEQVTNLEKTSKESGEKMAHMEKELQKMTGIANENHNTLNTAQDELVTFSEELAQLYHHVCLCNNETPNRVMLDYYRQSRVTRSGSLKGPDDPRGLLSPRLSRR--GVSSPVESRTSSEPVSKE---NTETSKEPSPTKTPTISPVITAPPSS-PVLDTSDIRKEPMNIYNLNAIIRDQIKHLQKAVDRSLQLSRQRAAAR---ELAPMIDKDKEALMEEILKLKSLLSTKREQIATLRAVLKANKQTAEVALANLKNKYENEKAMVTETMTKLRNELKALKEDAATFSSLRAMFATRCDEYVTQLDEMQRQLAAAEDEKKTLNTLLRMAIQQKLALTQRLEDLEFDHEQSRRSKG-KLGKSKIGSPKVSGEAPATVPTIDTYLLHSQGPQIPTIRVSSGTQRKRQFSPSLCDQSRPRTSGASYLQNLLSVPPDPTSTESFLLKGS----PSMSELIQGHRLSKEKRLTVAPPAKRDCQQPAASVPPQCSQLAGRQDYPTVSPDIALSKEQPHSSSQCAPLHCLAKPPYP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96G01-1", "uniprot_id": "BICD1_HUMAN", "id": "Q96G01-1", "name": "Protein bicaudal D homolog 1", "aln": "-----MAAEEVLQTVDHYKTEIERLTKELTETTHEKIQAAEYGLVVLEEKLTLKQQYDELEAEYDSLKQELEQLKEAFGQSFSIHRKVAEDGETREETLLQESASKEAYYLGKILEMQNELKQSRAVVTNVQAENERLTAVVQDLKENNEMVELQRIRMKDEIREYKFREARLLQDYTELEEENITLQKLVSTLKQNQVEYEGLKHEIKRFEEETVLLNSQLEDAIRLKEIAEHQLEEALETLKNEREQKNNLRKELSQYISLND------NHISIS-VDGLKFAEDGSEPNNDDKMNGHIHGPLVKLNGDYR-----TPTLRKGESLNPVSDLFSELNISEIQKLKQQLMQVEREKAILLANLQESQTQLEHTKGALTEQHERVHRLTEHVNAMRGLQSSKELKAELDGEKGRDSGEEAHDYEVDINGLEILECKYRVAVTEVID-LKAEIKALKEKYNKSVENYTDEKAKYESKIQMYDEQVTSLEKTTKESGEKMAHMEKELQKMTSIANENHSTLNTAQDELVTFSEELAQLYHHVCLCNNETPNRVMLDYYRQSRVTRSGSLKGPDDPRGLLSPRLARR--GVSSPVETRTSSEPVAKE---STEASKEPSPTKTPTISPVITAPPSS-PVLDTSDIRKEPMNIYNLNAIIRDQIKHLQKAVDRSLQLSRQRAAAR---ELAPMIDKDKEALMEEILKLKSLLSTKREQIATLRAVLKANKQTAEVALANLKNKYENEKAMVTETMTKLRNELKALKEDAATFSSLRAMFATRCDEYVTQLDEMQRQLAAAEDEKKTLNTLLRMAIQQKLALTQRLEDLEFDHEQSRRSKG-KLGKSKIGSPKVSGEASVTVPTIDTYLLHSQGPQTPNIRVSSGTQRKRQFSPSLCDQSRPRTSGASYLQNLLRVPPDPTSTESFLLKGP----PSMSEFIQGHRLSKEKRLTVAPP---DCQQPAASVPPQCSQLAGRQDCPTVSPDTALPEEQPHSSSQCAPLHCLSKPPHP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BR07-1", "uniprot_id": "BICD1_MOUSE", "id": "Q8BR07-1", "name": "Protein bicaudal D homolog 1", "aln": "-----MAAEEALKTVDQYKTEIERLTKELTETTHEKIQAAEYGLVVLEEKLTLKQQYDELEAEYDGLKQELEQLREAFGQSFSIHRKVAEDGETREETLLQESASKEAYYLNKILEMQNELKQSRAVVTNVQAENERLSAVVQELKENNEMVELQRIRMKDEIREYKFREARLLQDYTELEEENITLQKLVSTLKQNQVEYEGLKHEIKRFEEETVLLNSQLEDAIRLKEIAEHQLEEALETLKNEREQKNNLRKELSQYINLSD------SHISIS-VDGLKFAEDGSEPNNDDKMNGHIHGPLGKLNGDYR-----TPTTRKGESLHPVSDLFSELNISEIQKLKQQLIQVEREKAILLANLQESQTQLEHTKGALTEQHERVHRLTEHVNAMRGLQNSKEIKAELDCEKGRNSAEEAHDYEVDINGLEILECKYRVAVTEVID-LKAEIKALKEKYNKSVENYTEEKTKYESKIQMYDEQVTNLEKTSKESGEKMAHMEKELQKMTGIANENHNTLNTAQDELVTFSEELAQLYHHVCLCNNETPNRVMLDYYRQSRVTRSGSLKGPDDPRGLLSPRLSRR--GVSSPVESRTSSEPVSKE---NTETSKEPSPTKTPTISPVITAPPSS-PVLDTSDIRKEPMNIYNLNAIIRDQIKHLQKAVDRSLQLSRQRAAAR---ELAPMIDKDKEALMEEILKLKSLLSTKREQIATLRAVLKANKQTAEVALANLKNKYENEKAMVTETMTKLRNELKALKEDAATFSSLRAMFATRCDEYVTQLDEMQRQLAAAEDEKKTLNTLLRMAIQQKLALTQRLEDLEFDHEQSRRSKG-KLGKSKIGSPKIVSS---------------------------------------------------------LLPPYRHSAHN------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8N7T6T3-1", "uniprot_id": "A0A8N7T6T3_DANRE", "id": "A0A8N7T6T3-1", "name": "", "aln": "----MAAGGGCGESVDQYRSEVERLTRELAEANREKIRAAECGLVVLEENQKLKHQYAELEIEQEALKQELEQLQEAFGQAYTNQRKVAEDGETNEETLLQESASKEAYYMGRLDDLQSQLKVSSSAASNAQAETEHLNALMQELRENNETLELQRSRMREEIREYKFREARLLQDYTELEEENITLQKLVSTLKQNQVEYEGLKHEIKVLEEETVLLNSQLEDALRLKDISQGQLEEALDSLKSEREQKNNLRKELAHHLSLTDSVYGASTHLAISAVEGLKFAEEAATNGTSASGTSPNNEDSNRCNNECNGHGPKGEYHRRKTEMLPVSDLFSELNLSEIQKLKQQLIQVEREKALLLTNLQESQTQLQHTQGALTEQHRRVHRLTERVNAMKRLHNDKEFDTE-ESEKGDGPINGCCEFETDINGIELLECKYRVAVTEVID-LKAELKVLKEKYNQSLESQSEESNHSDGKVHALEEQVKQLEKSCREARERVSSLEAELRCASGMASESNGMLNAAQDELVTFSEELAQLYHHVCLCNNETPNRVMLDYYRQSRVTRSGSLKGPEDPRALLSPRLARRLAAVNSSDMSKSPQDSPSKEPLGDGIKGEGGSPNRTPFGSPINGSSLSSSTIPETGDLRREPMNIYNLNAIIRDQIKHLQKAVDRSLQLSRQRAAAR---ELAPILDKDKEACMEEILKLKSLLSTKREQIATLRLVLKANKQTAEVALANLKSKYENEKCMVTETMMKLRNELKALKEDAATFSSLRAMFATRCDEYVTQLDEMQRQLAAAEDEKKTLNSLLRMAIQQKLALTQRLEDLEFDHEQSHCGRGGKVPKIKSSPQKVSLGTALTAP-------------------PSPTASKPPSFPFQNNVVASASSSPSLDVPTPSSSLWTSSTQPFFLGQSQWNLGTQTLVLDPETLSIEFCQVVHSR---DSDAHVARSAPTSPYLGARQQSQRSMRSRIRSDLIQFKTARNSRIPSADPE---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P16568-1", "uniprot_id": "BICD_DROME", "id": "P16568-1", "name": "Protein bicaudal D", "aln": "MSSASNNGPSADQSVQDLQMEVERLTRELDQVSSASAQSAQYGLSLLEEKSALQQKCEELETLYDNTRHELDITQEALTKFQTSQKVTNKTGIEQEDALLNESAARETSLNLQIFDLENELKQLRHELERVRNERDRMLQENSDFGRDKSDSEADRLRLKSELKDLKFRETRMLSEYSELEEENISLQKQVSSLRSSQVEFEGAKHEIRRLTEEVELLNQQVDELANLKKIAEKQMEEALETLQGEREAKYALKKELDGHLNRES-----MYHISNLAYSIRSNMEDNASNNSDGEEE---NLALKRLEADLS--------TELKSPDGTKCDLFSEIHLNELKKLEKQLESMESEKTHLTANLREAQTSLDKSQNELQNFMSRLALLAAHVDALVQLK--KQIDVK---EQGKEGGQKKDELEQQLRALISQYANWFTLSAKEIDGLKTDIAELQKGLN------------YTDATTTLRNEVTNLKNKLLATEQKSLDLQSDVQTLTHISQNAGQSLGSARSTLVALSDDLAQLYHLVCTVNGETPTRVLLDHKTDDMSFENDSLT------AIQSQFKS------------------------------------DVFIAKPQIVEDLQG--LADSVEIKK-------YVDTVSDQIKYLKTAVEHTIDMNKHKIRSEGGDALEKVNTEEMEELQEQIVKLKSLLSVKREQIGTLRNVLKSNKQTAEVALTNLKSKYENEKIIVSDTMSKLRNELRLLKEDAATFSSLRAMFAARCEEYVTQVDDLNRQLEAAEEEKKTLNQLLRLAVQQKLALTQRLEEMEMDREMRHVRRPMPAQRGTSGKSSFSTRPS-------------------------------------------------------SRNPASSNANPF-----------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . ::*:. : *:****:** :.. . ::*: ** :***: *::: *** : ::**: :**: : : :: . : * .*::**:***::*: :: :::.:** ..: * ::: .:: .::. * :* *::.*::: ****:*:*.:*:*******:*** **:*:..***:** ****: : **. ***.*::: .**.*:: *:****::*:.*** * *:*** ::. . *:: . . *: : ... . : : : : . . .*****:::.*::**::** .:* **: * :**:*:**.*::::. * : *: *: :*:*: *: *::..: *:* : : * ::..: .:: . :: ** **::: *:: * . ::*..*::. : :: :: ::: : ::.: *.:*:. **::*::****** ** *.***.**:**: :. ...**. .: * : . .* .. : :: :::: : ****:*:.**::::::.::: :. * : :: * *:*:*******.*****.*** ***:*********:***.****** :*::** ******: ****************:**:*****:*:::*** ***:****** ***:*:***********::*:*:* : : : . . .. .:. ", "identical_positions": 264, "similar_positions": 272, "identity": "26.14%" }, { "cls_id": "homologset.agr.MGI:1101765", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AEG5-1", "uniprot_id": "A0A8I6AEG5_RAT", "id": "A0A8I6AEG5-1", "name": "RING-type E3 ubiquitin transferase", "aln": "MGQGSSKPVRPPPAGGYQSGPGRSYGRRHAYVSFRPSMSQQERIASQRRTTSEVPMHRSTANQS-KRSRSPFASTRRRWEDNEGSGASLAVENEDYSRYPPREYRASGSRRGMAYGHIDTLVARDSEEEGAGPVDRLPVRGKTGKFKDD----PEKGARSSR-----FSSVNHDVKEERGKVESPPAARCSARRAELSKQNGSLASQISSAEGRAAVKGNHS-LERERQNLPARPSRAPVSICG---------GGENTPKSAEEPVVRPKVRNVAAPNCMKPKVFFDTDDDDDVPHSTSRWRDAADAEEAHADGLARR-GRGEAAGGSSEPRYAEDQ-DARNEQAKPEKVSRRRRTMADPDFWAYSDDYYRYYEEDSDSDKEWMAALRRKYRSRDQPQSSSGESWEPLPGKEDQEPQQARGNVNT-----------AGAGSLAGAGSNGSGYPEEVQEPSLQEEEQASLEEGEIPWLRYNENE-SSSEGDNESTHELMQPGMFMLDGNNNLEDDSSVSEDLEVDWSLFDGFADGLGVAEAISYVDP-QFLTYMALEERLAQAMETALAHLESLAVDVEVANPPASKESIDALPEILVTEDHGAVGQEMCCPICCSEYVKGEVATELPCHHYFHKPCVSIWLQKSGTCPVCRCMFPPPL-------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O55176-3", "uniprot_id": "PJA1_MOUSE", "id": "O55176-3", "name": "E3 ubiquitin-protein ligase Praja-1", "aln": "-------------------------------------MSHQERIASQRRTTAEVPMHRSTANQS-KRSRSPFASTRRRWDDSESSGASLAVESEDYSRYPPREYRASGSRRGLAYGHIDTVVARDSEEEGAGPVDRLPVRGKAGKFKDD----PEKGARSSR-----FTSVNHDAKEECGKVESPPAARCSARRAELSKQNGSSASQISSAEGRAAAKGNNS-LERERQNLPARPSRAPVSICG---------GGENTPKSAEEPVVRPKVRNVATPNCMKPKVFFDTDDDDDVPHSTSRWRDAADAEEAHAEGLARR-GRGEAAS-SSEPRYAEDQ-DARSEQAKADKVPRRRRTMADPDFWAYTDDYYRYYEEDSDSDKEWMAALRRKYRSREQPQSSSGESWELLPGKEELERQQ------------------AGAGSLASAGSNGSGYPEEVQDPSLQEEEQASLEEGEIPWLRYNENE-SSSEGDNESTHELIQPGMFMLDGNNNLEDDSSVSEDLEVDWSLFDGFADGLGVAEAISYVDP-QFLTYMALEERLAQAMETALAHLESLAVDVEVANPPASKESIDALPEILVTEDHGAVGQEMCCPICCSEYVKGEVATELPCHHYFHKPCVSIWLQKSGTCPVCRCMFPPPL-------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NG27-1", "uniprot_id": "PJA1_HUMAN", "id": "Q8NG27-1", "name": "E3 ubiquitin-protein ligase Praja-1", "aln": "MGQESSKPVWPNPTGGYQSNTGRRYGRRHAYVSFRPPTSQRERIASQRKTNSEVPMHRSAPSQTTKRSRSPFSTTRRSWDDSESSGTNLNIDNEDYSRYPPREYRASGSRRGMAYGHIDSYGADDSEEEGAGPVERPPVRGKTGKFKDDKLYDPEKGARSLAGPPPHFSSFSRDVREERDKLDPVPAARCSASRADFLPQS-SVASQ-SSSEGKLATKGDSSERERREQNLPARPSRAPVSICG---------GGENTSKSAEEPVVRPKIRNLASPNCVKPKIFFDTDDDDDMPHSTSRWRDTANDNEGHSDGLARR-GRGESSSGYPEPKYPEDKREARSDQVKPEKVPRRRRTMADPDFWTHSDDYYKYCDEDSDSDKEWIAALRRKYRSREQTLSSSGESWETLPGKEEREPPQAKVSASTGTSPGPGASASAGAGAGASAGSNGSNYLEEVREPSLQEE-QASLEEGEIPWLQYHEND-SSSEGDNDSGHELMQPGVFMLDGNNNLEDDSSVSEDLEVDWSLFDGFADGLGVAEAISYVDP-QFLTYMALEERLAQAMETALAHLESLAVDVEVANPPASKESIDALPEILVTEDHGAVGQEMCCPICCSEYVKGEVATELPCHHYFHKPCVSIWLQKSGTCPVCRCMFPPPL-------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AZZ7-1", "uniprot_id": "A0A8M3AZZ7_DANRE", "id": "A0A8M3AZZ7-1", "name": "RING-type E3 ubiquitin transferase", "aln": "MGQEAGKSAWPKPAGGYQTISGRRYGRRHAYISFKPFTDKQRATSTVDCQNMQRTSDQKSQAMESKGNISSVLQTILPISCTN----SVRPEINAAAHHPEGHNRRHSSLRRVPKAPLNHFKRPKNDQVVPYDRKHCSGREKSKVWPIDENHKTNSKALSYINIDAYEPDSSGAEEEDLSSDPSHAACRRLDGICELGGNVDSLDDSRSSLFRKNRMKQMASSKDSTDLFDDTPDCQRTVKTNGKPSFFLEDGAPKCYGDTASAVSHKNKEQNNPGETFESEMVVRPKIRKQTSETHLERRKRSEKEETGHLSGSAIRNKCGSAPPGFLAQTCPENEFLFNFPAMALSDLNSEDRKSEDE--YAKVEDEDDIWEDLENFGEKCEPSMKADESSSEFSEGEWSASWTSDSGLDKERCTSEES--------------WETLPGIDEPPASRSSSLEEVPSLNLALEEQTPLEEGEIPWLMYNEDSGSSSDEDPDGVSQFVHPGLFILDGNNNLEDDSSMSEDLDTEWRFLDEFGDGFGMAQAISYVDHSQLLTYMALEERLAQAMEAALAHLESLAIDVEQAHPPATEQIIDCLPQITMHAEN--IEQEQCCAICCCEYVKDEIATLLPCRHMFHKLCVTLWLRKSGTCPVCRHVLTPAVTTDPASLSSEQETSPSTHSASGGAC", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .::. :: . : . .:.: * . *.. * . .: .: : : :::* . * .* * :. . :: ..:: . .: . * *: : * .:. * * .. . .*: .. . .*.* .:: : * .. ** : * * : : .: .*. * . : .:*. : * :* . . . :. . .: .* : : . : .* .* * * *.:. .*:: . ..: . *. * :: :* :: .: .:: .::: . * : . .. . ** .* :. . . . . :. *. *** . .* * *:.********* *:*:. ***: * :. ::::**:*:************:****:.:* ::* *.**:*:*:****** *:***************:*********:*** *:***::: **.**:* : :: : ** **.***.****.*:** ***:* *** **::**:********* ::.*.: ", "identical_positions": 165, "similar_positions": 185, "identity": "24.16%" }, { "cls_id": "homologset.agr.MGI:1101768", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6NXT2-1", "uniprot_id": "H3C_HUMAN", "id": "Q6NXT2-1", "name": "Histone H3.3C", "aln": "MARTKQTARKSTGGKAPRKQLATKAARKSTPSTCGVK-PHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFNTDLRFQSAAVGALQEASEAYLVGLLEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P84245-1", "uniprot_id": "H33_RAT", "id": "P84245-1", "name": "Histone H3.3", "aln": "MARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P84243-1", "uniprot_id": "H33_HUMAN", "id": "P84243-1", "name": "Histone H3.3", "aln": "MARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PI20-1", "uniprot_id": "H33_DANRE", "id": "Q6PI20-1", "name": "Histone H3.3", "aln": "MARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "C0HL66-1", "uniprot_id": "H33A_DROME", "id": "C0HL66-1", "name": "Histone H3.3A", "aln": "MARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "C0HL67-1", "uniprot_id": "H33B_DROME", "id": "C0HL67-1", "name": "Histone H3.3B", "aln": "MARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P84244-1", "uniprot_id": "H33_MOUSE", "id": "P84244-1", "name": "Histone H3.3", "aln": "MARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P61830-1", "uniprot_id": "H3_YEAST", "id": "P61830-1", "name": "Histone H3", "aln": "MARTKQTARKSTGGKAPRKQLASKAARKSAPSTGGVKKPHRYKPGTVALREIRRFQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAIGALQESVEAYLVSLFEDTNLAAIHAKRVTIQKKDIKLARRLRGERS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**********************:******:*** *** ****:***********:************************:*******:*:*****: *****.*:*****.********* ***:****:****:", "identical_positions": 117, "similar_positions": 14, "identity": "86.03%" }, { "cls_id": "homologset.agr.MGI:1101770", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6MGB6-1", "uniprot_id": "RING1_RAT", "id": "Q6MGB6-1", "name": "E3 ubiquitin-protein ligase RING1", "aln": "MTTPANAQNASKTWELSLYELHRTPQEAIMDGTEIAVSPRSLHSELMCPICLDMLKNTMTTKECLHRFCSDCIVTALRSGNKECPTCRKKLVSKRSLRPDPNFDALISKIYPSREEYEAHQDRVLIRLSRLHNQQALSSSIEEGLRMQAMHRAQRVRRPMPGSDQTTTMSGGEGE-------PGEGEGDGEDIS-----SDSAP---DSAPGPAPKRPRGGGAGGSSVGTGGGAAGGACGGAGSEDSGDRGGT--LGGGTLGPPSPPGAPSPPEPGGEIELVFRPHPLLV----EKGEYCQTRYVKTTGNATVDHLSK---YLALRIALERRQQQETVEPGGPGGGASDTGG---------PDGGGGERGVSGGGEGPEEPALPSLEGVSEKQYTIYIAPGGGAFTTLNGSLTLELVNEKFWKVSRPLELCYAPTKDPK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35730-1", "uniprot_id": "RING1_MOUSE", "id": "O35730-1", "name": "E3 ubiquitin-protein ligase RING1", "aln": "MTTPANAQNASKTWELSLYELHRTPQEAIMDGTEIAVSPRSLHSELMCPICLDMLKNTMTTKECLHRFCSDCIVTALRSGNKECPTCRKKLVSKRSLRPDPNFDALISKIYPSREEYEAHQDRVLIRLSRLHNQQALSSSIEEGLRMQAMHRAQRVRRPMPGSDQTATMSGGEGE-------PGEGEGDGEDVS-----SDSAP---DSAPGPAPKRPRGAGAGASSVGTGGGAAGGACGGAGSEDSGDRGGT--LGGGTLGPPSPPGAPSPPEPGGEIELVFRPHPLLV----EKGEYCQTRYVKTTGNATVDHLSK---YLALRIALERRQQQETTEPGGPGGGASDTGG---------PDGGGGERGVAGGGEGPEEPALPSLEGVSEKQYTIYIAPGGGAFTTLNGSLTLELVNEKFWKVSRPLELCYAPTKDPK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q06587-1", "uniprot_id": "RING1_HUMAN", "id": "Q06587-1", "name": "E3 ubiquitin-protein ligase RING1", "aln": "MTTPANAQNASKTWELSLYELHRTPQEAIMDGTEIAVSPRSLHSELMCPICLDMLKNTMTTKECLHRFCSDCIVTALRSGNKECPTCRKKLVSKRSLRPDPNFDALISKIYPSREEYEAHQDRVLIRLSRLHNQQALSSSIEEGLRMQAMHRAQRVRRPIPGSDQTTTMSGGEGE-------PGEGEGDGEDVS-----SDSAP---DSAPGPAPKRPRGGGAGGSSVGTGGGGTGGVGGGAGSEDSGDRGGT--LGGGTLGPPSPPGAPSPPEPGGEIELVFRPHPLLV----EKGEYCQTRYVKTTGNATVDHLSK---YLALRIALERRQQQEAGEPGGPGGGASDTGG---------PDGCGGEGGGAGGGDGPEEPALPSLEGVSEKQYTIYIAPGGGAFTTLNGSLTLELVNEKFWKVSRPLELCYAPTKDPK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VB08-1", "uniprot_id": "RING1_DROME", "id": "Q9VB08-1", "name": "E3 ubiquitin-protein ligase RING1", "aln": "MTSLDPAPN--KTWELSLYELQRKPQEVITDSTEIAVSPRSLHSELMCPICLDMLKKTMTTKECLHRFCSDCIVTALRSGNKECPTCRKKLVSKRSLRADPNFDLLISKIYPSREEYEAIQEKVMAKFNQTQSQQALVNSINEGIKLQSQNRPQRFRTKGGGGGGGGGGNGNGAANVAAPPAPGAPTAVGRNASNQMHVHDTASNDSNSNTNSIDRENRDPGHSGTSAASAITSASNAAPSSSANSGASTSATRMQVDDASNPPSVRSTPSPVPSNSSSSKPKRAMSVLTSERSEESESDSQMDCRTEGDSNIDTEGEGNGELGINDEIELVFKPHPTEMSADNQLIRALKENCVRYIKTTANATVDHLSKYLAMRLTLDLGADLPEACRVLNFCIYVAPQPQQLVILNGNQTLHQVNDKFWKVNKPMEMYYSWKKT--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**: * * **********:*.***.* *.************************:*****************************************.***** ************** *::*: ::.: :.**** .**:**:::*: :*.**.* *.. .*. . ** . *.: * *:*. :* ... :. *. * ..:*..:. .:... .:.::.... ..* ..: .*** .:*** .... . *. .:*. *:.* . :* *::.:* .: *.:. :* : .. * .. . .:. .. . . . : . *. :: **:** :. ***. **. **:*****.:*:*: *: .* ", "identical_positions": 169, "similar_positions": 125, "identity": "38.5%" }, { "cls_id": "homologset.agr.MGI:1101771", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z2Y9-1", "uniprot_id": "KLOT_RAT", "id": "Q9Z2Y9-1", "name": "Klotho", "aln": "MPAR------APPRRLPRLLLLRLLSLHLLLLTLR-------------------------ARCLSAEPGQGAQTWARFARPPVPEASGLLHDTFPDGFLWAVGSAAYQTEGGWRQHGKGASIWDTFTHHPRAIPEDSPIVMAPSGAPLPPLPSTGDVASDSYNNVYRDTEGLRELGVTHYRFSISWARVLPNGTAGTPNREGLRYYRRLLERLRELGVQPVVTLYHWDLPQRLQDTYGGWANRALADHFRDYAELCFRHFGGQVKYWITIDNPYVVAWHGYATGRLAPGVRGSSRLGYLVAHNLLLAHAKVWRLYNTSFRPTQGGRVSIALGSHWITPRR-MTDYHIRECQKSLDFVLGWFAKPIFIDG-DYPKSMKNNLSSLLPDFTESEKRFIRGTADFFALSFGPTLSFQLLDPSMKFRQLESPSLRQLLSWIDLEYNHPQIFIVENGWFVSGTTRRDDAKYMYYLKKFIMESLKAIRLDGVDVIGYTAWSLMDGFEWHRGYSIRRGLFYVDFLSQDKELLPKSSALFYQKLIENNGFPPLPENQPLEGTFPCDFAWGVVDNYIQVDPTLSQFTDPNVYLWDVHHSKRLIKVDGVVAK--KRKPYCVDFSAIRPQITLLREMRVTHFRFSLDWALILPLGNQTQVNRTVLHFYRCMVSELVHANITPVVALWQPATPHQGLPHALAKHGAWENPHTALAFADYANLCFEELGHWVKFWITINEPNSRNMTYRAGHHLLKAHALAWHLYDDKFRAAQKGKISIALQVDWIEPACPFSQKDKEVAERVLEFDVGWLAEPIFGSGDYPHVMREWLNQKN-----NFLLPYFTEDEKKLIRGSFDFLALSHYTTILVDWEKED-------PIKYNDYLEVQEMTDITWLNSPNQ-VAVVPWGLRKALNWLRFKYGDLPMFVTANGIDDDPHAEQDSLRMYYIKNYVNEALKAYVLDGINLCGYFAYSLSDRSVPKSGFYRYAANQFEPKPSIKHYRKIIDNNGFLGSGTLGRFCPEEYTVCTGCGFFQTRKSLLAFISFLVFAFVTSLALIYYYSKKGRRRYK---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35082-1", "uniprot_id": "KLOT_MOUSE", "id": "O35082-1", "name": "Klotho", "aln": "MLAR------APPRRPPRLVLLRLLLLHLLLLALR-------------------------ARCLSAEPGQGAQTWARFARAPAPEAAGLLHDTFPDGFLWAVGSAAYQTEGGWRQHGKGASIWDTFTHHSGAAPSDSPIVVAPSGAPSPPLSSTGDVASDSYNNVYRDTEGLRELGVTHYRFSISWARVLPNGTAGTPNREGLRYYRRLLERLRELGVQPVVTLYHWDLPQRLQDTYGGWANRALADHFRDYAELCFRHFGGQVKYWITIDNPYVVAWHGYATGRLAPGVRGSSRLGYLVAHNLLLAHAKVWHLYNTSFRPTQGGRVSIALSSHWINPRR-MTDYNIRECQKSLDFVLGWFAKPIFIDG-DYPESMKNNLSSLLPDFTESEKRLIRGTADFFALSFGPTLSFQLLDPNMKFRQLESPNLRQLLSWIDLEYNHPPIFIVENGWFVSGTTKRDDAKYMYYLKKFIMETLKAIRLDGVDVIGYTAWSLMDGFEWHRGYSIRRGLFYVDFLSQDKELLPKSSALFYQKLIEDNGFPPLPENQPLEGTFPCDFAWGVVDNYVQVDTTLSQFTDPNVYLWDVHHSKRLIKVDGVVAK--KRKPYCVDFSAIRPQITLLREMRVTHFRFSLDWALILPLGNQTQVNHTVLHFYRCMISELVHANITPVVALWQPAAPHQGLPHALAKHGAWENPHTALAFADYANLCFKELGHWVNLWITMNEPNTRNMTYRAGHHLLRAHALAWHLYDDKFRAAQKGKISIALQADWIEPACPFSQNDKEVAERVLEFDIGWLAEPIFGSGDYPRVMRDWLNQKN-----NFLLPYFTEDEKKLVRGSFDFLAVSHYTTILVDWEKED-------PMKYNDYLEVQEMTDITWLNSPSQ-VAVVPWGLRKVLNWLRFKYGDLPMYVTANGIDDDPHAEQDSLRIYYIKNYVNEALKAYVLDDINLCGYFAYSLSDRSAPKSGFYRYAANQFEPKPSMKHYRKIIDSNGFLGSGTLGRFCPEEYTVCTECGFFQTRKSLLVFISFLVFTFIISLALIFHYSKKGQRSYK---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UEF7-1", "uniprot_id": "KLOT_HUMAN", "id": "Q9UEF7-1", "name": "Klotho", "aln": "MPAS------APPRR-PRPPPP-SLSLLLVLLGLG-------------------------GRRLRAEPGDGAQTWARFSRPPAPEAAGLFQGTFPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPLQPATGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLLERLRELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITIDNPYVVAWHGYATGRLAPGIRGSPRLGYLVAHNLLLAHAKVWHLYNTSFRPTQGGQVSIALSSHWINPRR-MTDHSIKECQKSLDFVLGWFAKPVFIDG-DYPESMKNNLSSILPDFTESEKKFIKGTADFFALCFGPTLSFQLLDPHMKFRQLESPNLRQLLSWIDLEFNHPQIFIVENGWFVSGTTKRDDAKYMYYLKKFIMETLKAIKLDGVDVIGYTAWSLMDGFEWHRGYSIRRGLFYVDFLSQDKMLLPKSSALFYQKLIEKNGFPPLPENQPLEGTFPCDFAWGVVDNYIQVDTTLSQFTDLNVYLWDVHHSKRLIKVDGVVTK--KRKSYCVDFAAIQPQIALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELVRVNITPVVALWQPMAPNQGLPRLLARQGAWENPYTALAFAEYARLCFQELGHHVKLWITMNEPYTRNMTYSAGHNLLKAHALAWHVYNEKFRHAQNGKISIALQADWIEPACPFSQKDKEVAERVLEFDIGWLAEPIFGSGDYPWVMRDWLNQRN-----NFLLPYFTEDEKKLIQGTFDFLALSHYTTILVDSEKED-------PIKYNDYLEVQEMTDITWLNSPSQ-VAVVPWGLRKVLNWLKFKYGDLPMYIISNGIDDGLHAEDDQLRVYYMQNYINEALKAHILDGINLCGYFAYSFNDRTAPRFGLYRYAADQFEPKASMKHYRKIIDSNGFPGPETLERFCPEEFTVCTECSFFHTRKSLLAFIAFLFFASIISLSLIFYYSKKGRRSYK---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58GMY9-1", "uniprot_id": "A0AC58GMY9_DANRE", "id": "A0AC58GMY9-1", "name": "", "aln": "MAGGNRGTWGKPSRRKSVILWRPELRSAWIPIYPSSAWVIIDRFPERTTTKKTGPDGLHHSEGTASDPGAGQHTWDTFSKLPYPDDKAFLYDTFPDKFMWAVGTAAYSVEGAWEKDGKGKSIWDTFTRG-------------------GTRVSRGDVGSDSYHNIPGDLRALQQLGVSHYRFSLSWPRIFSNGTKESYNDKGVEYYKNLIRGLKDIKVQPVVTLYHWDLPDSLQTLFGGWSNSVMVELFRDYADFCFKTFGSDVKFWITIDNPFVVAWHGYGTGVVAPGIKNDSDLPFRVGHNLLKAHAAAWHLYDERYRAAQGGRVSMALGSHWIKPSR-TRQESRKACQRSLNFVLGWFARPLFVDG-DYPPCMKDNLTHRLPSFTEAESAYVNGTADFFALSHGPALSFQLINDSLRFGQTEDLGLRMLLYWVRAEYNNPPIFVVESGWYGSGNTKTKDAKHMYYLKRFIMETLKAIHVDRVNVIGYTAWSLLDGYEWYREYAIRRGLFYVDFNTPDLKREPKASATFYSKLIEKNGFPQLPENRPAHGAFPCDFAWGVAANSIQVDTTPTQFTDTNVYIWNISGNGELKKLPGLQAPHLRRTPHCADYGSIRQQVSDLLRMQVSHFHFSLNWSSIVPTGHVSDANETLLRYYYCFVSELQKVNITPVVTLWHHTGKLSSLPAPMEASDGWQSEKTVQAFVDYARLCFHRLGAHVKLWITLNEPNDEDLEYTVGHQLLRAHALAWHVYDREFRKAQGGKASLVLHMDWVEPAFSFNREDVAPADRVLDFRVGWFAEPIFGKGDYPAVMRSWLQQRNTIDLFNYHLPTFSEEDRLLVKGTYDFFAISHFTTSMVYDGVED-------KYTFKDKLQVQLISDVTWIMSPRRNSPVVPWGLRKALNWVNSRYKGVPIYVMANGVQEDTARFKDSLRSYYLYNYVNEALKAYMLDAVNLKGYFAYAFSDQRDPGFGMYGHVQEEVISKSSLGHYKNIIRHNGFPAPGTSQHQCPHAPAQGSGR-YVLTKKPVVGFLSLVSSCMLITMCLVIYYAFKRHKLTTKK-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VV98-1", "uniprot_id": "Q9VV98_DROME", "id": "Q9VV98-1", "name": "Cytosolic beta-glucosidase", "aln": "-------------------MMQIILPLFVLT--------------------------------------------ASCLGSPVSQTR-----RFPNDFLWGVGSSSYQIEGGWNADDKGESIWDFLTHTHP---------------EKIVDRSNGDVSADSYHQWKRDVQMVKELHVGTYRFSLSWPRIMPGGYMNHVSTAGIKYYSNLIDELLRYNITPMVTIYHWELPQKLQELGG-WTNPEIIPLFKDYARLVLEMYGDRVKIWTTVNEPWHVCEHGYGVDYMAPSYNYPGIPAYLCGHNLLKAHAEVVHMYRELFQPRQGGRMGITLDTSWPEPRDPNSAEDREASERAMQFYVGWFGHPIFSKHGNYPKVMIERIR--------------------------------------------------------------------------------------------------------------------------------------------------------NLSKEQGFGARSR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LPEFTTEEIHRIRGTSDFFGINSYTSNLVTSNGHNNTGKFPVPSFNHDMGVVESQEGVDWPGSGSVWLKVYPKGMYNLLMWIHREYNAPEIIVTENGVSD-RGGLEDYARVDYYNLYLSAVLDA-MEDGANISGYIAWSLMDSYEWKAGFSEKFGLYHVDFNSPQRTRTPKIS-----ARVFAQLCKTNTIDWSYRPKLDEEQQLVAMAQLPAEARTSGASGAVSWSLMGILLLALLR", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : * .: **: *:*.**:::*. **.*. ..** **** :*: : ***.:***:: * . :::* * ****:**.*::..* . *:.** .*: * : *:**:***:**: ** * *:* : *:*** : :. :*. ** * *:::*: *. ***... :**. . : .**** *** . ::* ::. ***::.::*.: * * . .:::::* :***.:*:* . :** * :.: :* :.:** .. ** *: :: ::*: **:.:. :*: :* .: :* *: .: * * * * *: : * *:. .* : : **:.: .* * * *:. .*.* : * *: **:*::: * *: * : :. . . : * : . .: :: : : . :: ", "identical_positions": 131, "similar_positions": 155, "identity": "12.3%" }, { "cls_id": "homologset.agr.MGI:1101778", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LVI0-1", "uniprot_id": "F1LVI0_RAT", "id": "F1LVI0-1", "name": "Tyrosine-protein kinase", "aln": "----------MDNNMDSKS-----------------------ILEELLLKKSQQKKKMSPINYKERLFVLTKTSLSYYEYDKMKRGSRKGSIEVKKIRCVEKVNLEEQTP---VERQYPFQIVYKDG---------------------------------LLYVYASNEESRCQWLKALQKEIR-GNPHLLIKYHSGFFVDGKFLCCQQSCKAAPGCTLWEAYADLHIAISDEKHRAPTFPERILKIPRAVP---ILKMDASS--------------------------SSAIPPQYDSHLKKSYDSQPTV----------------------NIRYIPREDCPDWWQIRKPKSE---EDIARSNQLERNIVSHSPSKMSWGFPESSS-----------SEEEENLDAYDWFAGNISRSQSEQLLRQKGKEGAFMVRNSSQMGMYTVSLFSKAVNDKKGTVKHYHVHTNAENKLYLAENYCFDSIPKLIHYHQHNSAGMITRLRHPVSTKANKVPVSVALGSGIWELKREEIALLKELGSGQFGVVQLGKWKGQYSVAVKMIKEGAMSEDEFFQEAQTMMKLSHPKLVKFYGVCSKKYPIYIVTEYITNGCLLNYLKNHGKGLESSQ--LLEMCYDVCEGMAFLESHQFIHRDLAARNCLVDSDLSVKVSDFGMTRYVLDDQYVSSVGTKFPVKWSAPEVFHYFKYSSKSDVWAFGILMWEVFSLGKQPYDLYDNSEVVVKVSQGHRLYRPQLASDTIYQIMYSCWHELPEKRPTFQQLLSAIEPLREQDKP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97504-1", "uniprot_id": "BMX_MOUSE", "id": "P97504-1", "name": "Cytoplasmic tyrosine-protein kinase BMX", "aln": "--------------MESKS-----------------------ILEELLLKKSQQKKKMSPNNYKERLFVLTKTSLSYYEYDKMKRGSRKGSIEIKKIRCVEKVNLEEQTP---VERQYPFQIVYKDG---------------------------------LLYVYASNEESRCQWLKALQKEIR-GNPHLLIKYHSGFFVDGKFLCCQQSCKAAPGCTLWEAYADLHIAISDEKHRAPTFPERLLKIPRAVP---VLKMDASS--------------------------SGAILPQYDSYSKKSCGSQPTS----------------------NIRYIPREDCPDWWQVRKLKSE---EDIACSNQLERNIASHSTSKMSWGFPESSS-----------SEEEENLHAYDWFAGNISRSQSEQLLRQKGKEGAFMVRNSSQMGMYTVSLFSKAVNDKKGTVKHYHVHTNAENKLYLAENYCFDSIPKLIHYHQHNSAGMITRLRHPVSTKANKVPVSVALGSGIWELKREEITLLKELGNGQFGVVQLGQWKGQYDVAVKMIKEGAMSEDEFFQEAQTMMKLSHPKLVKFYGVCSKKYPIYIVTEYITNGCLLNYLKSHGKGLESCQ--LLEMCYDVCEGMAFLESHQFIHRDLAARNCLVDSDLSVKVSDFGMTRYVLDDQYVSSVGTKFPVKWSAPEVFHYFKYSSKSDVWAFGILMWEVFSLGKQPYDLYDNSEVVVKVSQGHRLYRPQLASDTIYQIMYSCWHELPEKRPTFQQLLSAIEPLREQDKP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P51813-1", "uniprot_id": "BMX_HUMAN", "id": "P51813-1", "name": "Cytoplasmic tyrosine-protein kinase BMX", "aln": "--------------MDTKS-----------------------ILEELLLKRSQQKKKMSPNNYKERLFVLTKTNLSYYEYDKMKRGSRKGSIEIKKIRCVEKVNLEEQTP---VERQYPFQIVYKDG---------------------------------LLYVYASNEESRSQWLKALQKEIR-GNPHLLVKYHSGFFVDGKFLCCQQSCKAAPGCTLWEAYANLHTAVNEEKHRVPTFPDRVLKIPRAVP---VLKMDAPS--------------------------SSTTLAQYDNESKKNYGSQPPSSSTSLAQYDSNSKKIYGSQPNFNMQYIPREDFPDWWQVRKLKSSSSSEDVASSNQKERNVN-HTTSKISWEFPESSS-----------SEEEENLDDYDWFAGNISRSQSEQLLRQKGKEGAFMVRNSSQVGMYTVSLFSKAVNDKKGTVKHYHVHTNAENKLYLAENYCFDSIPKLIHYHQHNSAGMITRLRHPVSTKANKVPDSVSLGNGIWELKREEITLLKELGSGQFGVVQLGKWKGQYDVAVKMIKEGSMSEDEFFQEAQTMMKLSHPKLVKFYGVCSKEYPIYIVTEYISNGCLLNYLRSHGKGLEPSQ--LLEMCYDVCEGMAFLESHQFIHRDLAARNCLVDRDLCVKVSDFGMTRYVLDDQYVSSVGTKFPVKWSAPEVFHYFKYSSKSDVWAFGILMWEVFSLGKQPYDLYDNSQVVLKVSQGHRLYRPHLASDTIYQIMYSCWHELPEKRPTFQQLLSSIEPLREKDKH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P08630-1", "uniprot_id": "BTKL_DROME", "id": "P08630-1", "name": "Tyrosine-protein kinase Btk", "aln": "MMGTKHRNSHVNGSIKSSSSLRSSSKSFQAKMDLMSERLYDVVKSGSMVKRAQNKKRFTPVNYKHRWFELTKRTFSYFDVENVERRRERGRIHLKGVRLVEEATVSGEGGDPFAPDGYPFQVGYCEISASANSHQLENGNGGGSGVGIEGQQSGRAVPQYTLYVIANSEKERSEWIRAIRQVCEDSNTPKSYRYHPGLWSGKKWSCCKGLSRTTFGCRAAAHWREANNNPSNGSSPAQNSTRSISPNSSTTNSQFSLQHNSSGSLGGGVGGGLGGGGSLGLGGGGGGGGSCTPTSLQPQSSLTTFKQSPTLLNGNGTLLDANMPGGIPTPGTPNSKAKDNSHFVKLVVALYPFKAIEGGDLSLEKNAEYEVIDDSQE-HWWKVKDALGNVGYIPSNYVKPKALLGLERYEWYVGDMSRQRAESLLKQGDKEGCFVVRKSSTKGLYTLSLHTKVP---QSHVKHYHIKQNARCEYYLSEKHCCETIPDLINYHRHNSGGLACRLKSSPCDRP--VPPTAGLSHDKWEIHPMELMLMEELGSGQFGVVRRGKWRGSIDTAVKMMKEGTMSEDDFIEEAKVMTKLQHPNLVQLYGVCSKHRPIYIVTEYMKHGSLLNYLRRHEKTLIGNMGLLLDMCIQVSKGMTYLERHNYIHRDLAARNCLVGSENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEVLNYTRFSSKSDVWAYGVLMWEIFTCGKMPYGRLKNTEVVERVQRGIILEKPKSCAKEIYDVMKLCWSHGPEERPAFRVLMDQLALVAQTLTD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.:.* : . ::*::*:**:::* ***.* * *** .:**:: ::::* .:* *.:* :* **:..:. : . ****: * : *** *..*:.*.:*::*::: . .*. :**.*:: . *: **: .::: ** : : : .: . . . . : . :. *: ::.. * : . . .. ..*. * : ... . . *:: .:: * :: .: . * . :: . .: .*. *:*:.*::**.::*.**:* .***.*:**:** *:**:**.:*. :. *****:: **. : **:*::* ::**.**:**:***.*: **: . . :. ** :..*. . **:: *: *::***.******: *:*:*. ..****:***:****:*::**:.* **.**:**::******. ********:.:*.*****: * * * **:** :*.:**::** *::************. : ***:***::********.** *****:**:.***::* ::********:*:****:*: ** **. .*::** :*.:* * :*: .:. **::* ** . **:**:*: *:. : : : . ", "identical_positions": 247, "similar_positions": 235, "identity": "31.19%" }, { "cls_id": "homologset.agr.MGI:1101779", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P49744-1", "uniprot_id": "TSP4_RAT", "id": "P49744-1", "name": "Thrombospondin-4", "aln": "MTMITPSSKLTLTKGNKSWSSTRCGAFLLLHLVLQPWQRAGAQATPQVFDLLPSSSQRLNPAALQP-VLTDPTLHELYVISTFKLQSKS-------SATIFGLYSSSDNSKYFEFTVMGRLNKAILRYLKDDGKIHLVVFNNLQLADGRRHRILLRLSNLQRGAGS-------------VELYLDCVQVDSVNNLPRAFSGLTQNPQAIELRTFQRKPQDFLEELKLVVRGSLFQVASLQDC-----FLQQSEPLAATGTGDFNRQFLGQMTQLNQLLGEVKDLLRQQVKETSFLRNTIAECQACGPLSFQS----------------------------PTPNTLVPIAPPAPPTRPTRRCDSSPCFRGVRCTDTRDGFQCGPCPDGYTGNG------------------------------------------ITCSDVDECK-YHPCYPGVRCTNLAPGFRCDACPVGFTGPMVQGVGINFAKTN--KQVCTDVDECR---NGACVLNSICINTLGSYRCGPCKPGYTGDQTRGCRTE---------RSCRNPEQNPCSVHAQCIEERQGDVTCVCGVGWAGRAGYVCGKDVDIDSYPDEELPCSARNCKKDNCKYVPNSGQEDADRDGIGDACDEDADGDGILNEQDNCVLTHNVDQRNTDKDIFGDACDNCRGVLNNDQKDTDGDGKGDACDDDMDGDGIKNILDNCPRVPNRDQQDRDGDGVGDACDSCPDVSNPNQSDVDNDLVGDSCDTNQDSDGDGHQDSTDNCPTVINSAQLDTDKDGIGDECDDDDDNDGMPDLFPPGPDNCRLVPNPAQEDSNNDGVGDICEADFDQDKVIDRIDVCPENAEITLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTQTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATPFRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTSDQVRLLWKDSRNVGWKDKVSYRWFLQHRPQVGYIRVRFYEGSELVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIPEDFQEFQIQT-FDRLDN--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z1T2-1", "uniprot_id": "TSP4_MOUSE", "id": "Q9Z1T2-1", "name": "Thrombospondin-4", "aln": "--MPAPR--------------AAAAAFLLLHLVLQPWQRTSAQATPQVFDLLPSSSQRLNPSALQP-VLTDPTLHEVYLISTFKLQSKS-------SATIFGLYSSSDNSKYFEFTVMGRLNKAILRYLKNDGKIHLVVFNNLQLADGRRHRVLLRLSNLQRGDGS-------------VELYLDCAQADSVRNLPRAFSGLTQNPESIELRTFQRKPQDFLEELKLVVRGSLFQVASLQDC-----FLQQSEPLAATSTGDFNRQFLGQMTQLNQLLGEVKDLLRQQVKETSFLRNTIAECQACGPLSFQS----------------------------PTPNTLVPIAPPAPPTRPTRHCDSSPCFRGVRCTDTRDGFQCGPCPDGYTGNG------------------------------------------ITCSDVDECK-YHPCYPGVRCVNLAPGFRCDACPVGFTGPMVQGVGINFAKTN--KQVCTDVDECQ---NGACVLNSICINTLGSYRCGPCKPGYTGDQTRGCKTE---------RSCRNPEQNPCSVHAQCIEERQGDVTCVCGVGWAG-DGYVCGKDVDIDSYPDEELPCSARNCKKDNCKYVPNSGQEDADRDGIGDACDEDADGDGILNEQDNCVLTHNIDQRNSDKDIFGDACDNCRMVLNNDQKDTDGDGRGDACDDDMDGDGIKNILDNCPRVPNRDQQDRDGDDVGDACDSCPDVSNPNQSDVDNDLVGDSCDTNQDSDGDGHQDSTDNCPTVINSSQLDTDKDGIGDECDDDDDNDGIPDLVPPGPDNCRLVPNPAQEDSNNDGVGDICEADFDQDQVIDHIDVCPENAEITLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTQTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATPFRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTSDQVRLLWKDSRNVGWKDKVSYRWFLQHRPQVGYIRVRFYEGSELVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIPEDFQEFQTQS-FDRLDN--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P35443-1", "uniprot_id": "TSP4_HUMAN", "id": "P35443-1", "name": "Thrombospondin-4", "aln": "--MLAPR----------------GAAVLLLHLVLQRWLAAGAQATPQVFDLLPSSSQRLNPGALLP-VLTDPALNDLYVISTFKLQTKS-------SATIFGLYSSTDNSKYFEFTVMGRLNKAILRYLKNDGKVHLVVFNNLQLADGRRHRILLRLSNLQRGAGS-------------LELYLDCIQVDSVHNLPRAFAGPSQKPETIELRTFQRKPQDFLEELKLVVRGSLFQVASLQDC-----FLQQSEPLAATGTGDFNRQFLGQMTQLNQLLGEVKDLLRQQVKETSFLRNTIAECQACGPLKFQS----------------------------PTPSTVVPPAPPAPPTRPPRRCDSNPCFRGVQCTDSRDGFQCGPCPEGYTGNG------------------------------------------ITCIDVDECK-YHPCYPGVHCINLSPGFRCDACPVGFTGPMVQGVGISFAKSN--KQVCTDIDECR---NGACVPNSICVNTLGSYRCGPCKPGYTGDQIRGCKAE---------RNCRNPELNPCSVNAQCIEERQGDVTCVCGVGWAG-DGYICGKDVDIDSYPDEELPCSARNCKKDNCKYVPNSGQEDADRDGIGDACDEDADGDGILNEQDNCVLIHNVDQRNSDKDIFGDACDNCLSVLNNDQKDTDGDGRGDACDDDMDGDGIKNILDNCPKFPNRDQRDKDGDGVGDACDSCPDVSNPNQSDVDNDLVGDSCDTNQDSDGDGHQDSTDNCPTVINSAQLDTDKDGIGDECDDDDDNDGIPDLVPPGPDNCRLVPNPAQEDSNSDGVGDICESDFDQDQVIDRIDVCPENAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTQTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATPFRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTSDQVRLLWKDSRNVGWKDKVSYRWFLQHRPQVGYIRVRFYEGSELVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIPEDFQEFQTQN-FDRFDN--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8JGW0-1", "uniprot_id": "TSP4B_DANRE", "id": "Q8JGW0-1", "name": "Thrombospondin-4-B", "aln": "----------------------MAGTMHLLTAVSLILMLSSANAESTVYNLLTSP--DCLPDLLHG-GLAEQGVTELYILTTFRIQPGT-------GNTIFSLYNPRDNSKYFEFSVFGKANKAILRYLRRDGRMSAVTFNKLNLADGEKHRLLFHLKGLEVGHPGGFPHSQGALPVPGVELHLDCRLVETLRDLPAVFNGLN-NHQAVELKTMQGKAQEGLEELKLAYGDSVENVASLQDC-----HTQ-SDSVQALGLN--TKQLTTQMLELTKVINELKDVLIQQVKETSFLRNTISECQACG-------------------------------------------LSGAEVVKP--KCAPGVCFRDDMCIETAEGVECGPCPDGYTGDG------------------------------------------YSCDDVDECQ-FNPCFPGVRCVNMAPGFRCEACPLGFTGKPLEGVGVAYAQTH--KQVCDDIDECKGPDNGGCTANSICVNSVGSYQCGRCKTGFTGDQIRGCKPE---------KSCGNRLQNPCDPNAQCTEERDGTITCQCGIGWAG-NGYLCGKDTDIDGYPDERLRCRDPTCRKDNCVTVPNSGQEDADGDGKGDACDPDADGDGILNEQDNCWLTPNINQQNSDKDSHGDACDNCVRVDNPDQRDTDSDGLGDACDDDMDGDGLKNFLDNCQRVKNRDQLDRDGDGVGDACDSCPDIPNPNQSDIDNDLVGDSCDTNQDSDGDGHQDSKDNCPMVINSSQLDTDKDGIGDECDDDDDNDGIPDSLPPGPDNCRLVPNPEQIDDNNDGVGDICESDFDQDKVIDRIDNCPENAEITLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFSGVDFEGTFHVNTVTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATPFRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTNDQVRLLWKDPRNVGWKDKVSYRWYLQHRPQVGYIRVRFYEGTELVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIPEDFQEFSTQHGMDPL----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0R4I9N1-1", "uniprot_id": "A0A0R4I9N1_DANRE", "id": "A0A0R4I9N1-1", "name": "", "aln": "---------------------MSMWTRVIFSLQLILQLLDRVKSQGIVYDLLVSP--DCLPDLLQG-GIKAKNMDNVFILATLQMQSKT-------PTRVFHIFNALDNTDYFDFTVQGKLNRVILKYLKSNGKVGTTTFNKVPLTDGQHHHILLHFSGLQQGSSA-------------TALYVDCRLVDRVLDVPLAFKSLPQGPKRVTLKTLPTSTQDTLSDLKLVLDESIDNVVELQDCSTLSEMTEQKETLQLLGTT--SKVEAGPMFELMRMIQELKQKVDQQTKETADLKKTILECVPCNGLG--------------------------------------GQTHAGLQNKKPSNCGPGVCFTQDLCVEKADGVDCAPCPEGYTGDG------------------------------------------VHCEDVDECQ-FNPCFFGVRCVNTAPGFRCEQCPRGFSGPEVQGVGVNYAQTN--KQICNDIDECLVD-NGGCTPNSNCHNTMGAFHCGSCKAGFTGDQNSGCKTAGPDAVPPMDRLCGNGQPNPCDINAECVVERDGSISCVCKIGWAG-NGYVCGKDTDIDAYPDDILKCRDATCRKDNCMFVPNSGQEDADRDGKGDACDEDADSDGILNDQDNCWLTPNIDQKNSDKDLHGDACDNCIEIKNPDQRDTDNDGLGDACDDDIDGDGLKNILDNCQKVPNPDQKDKDHDGVGDACDSCPDVPNPNQSDIDNDLVGDTCDTNIDSDGDGHQNTKDNCPNVINSEQLDTDKDGLGDECDDDDDNDGILD----DNDNCRLVPNPDQKDENNDGVGDVCTGDFDKDHVIDRIDTCPENAEITLTDFRAYQTVVLDPEGEAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTVTDDDYAGFIFSYQDSSSFYVVMWKQTEQTYWQAVPFRAVAEPGIQLKAVKSNTGPGEFLRNSLWHTGDTKEQVRLLWKDPRNVGWKDKVSYRWNLKHRPQVGYIRVQFYEGTDLVADSGVVIDTSMRGGRLGVFCFSQENIIWSNLRYRCNDTIPEYYIEEQDQQ---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VM97-1", "uniprot_id": "Q9VM97_DROME", "id": "Q9VM97-1", "name": "", "aln": "--MNWTR------------VLLIGLTALALTFVDVASLSLDPVASAELEQFIRKGDVVISTRHIRPRRKLHISIEALFMIDFPMLKHKMSFFLDRKQQRVTLDISANGATESRNFEIPNINETSTIRSLALQFSKNRITLH-VDCKASTHHDIDMNLAKLYTQMDDPVIKLFRE---RKYPLHFDGDMEHSLQRANCQKGNHRRGNRRMLRNKITEREKNKKRDVRGWYEPTIAREGVVDHR-HQEVPTDVERGDIPVLNGDCEDALARSLSDLLALVKLLREDVAHQRQEIAYLRMLLENCAGCKNPLTTDNQLRIEPDCRSANPCYPGVECLDSAAGPRCGHCPLGFIGDGKSCKPGVTCAHHMCYPGVQCHDTVNGAQCDSCPAGYEGDGRTCSLRNPCLDTPCPSGAQCLQVGYPPYFHCISCPMGHEVNGTSCRDMNECLLYDPCDELATCTNLSPGFQCSPCPVGFDGTHAHGYFADYYSVDYRRQTCLDVDECRTG-FFRCPEHSTCINEIGSYRC-QCHEGYVTNGTYSCLDR--------SSVFMCPDGTVCDRNAVCLRMDNIRHKCHCNVGWAG-NGLICGRDTDVDGWPDQAIGCPELRCQRDNCPKLPNSGQEDADLDGHGDGCDDDADGDNVQNSQDNCWLAYNTEQLDSDGDKVGDVCDNCVLKYNPRQLDTDEDGLGDECDGDIDNDSIPNALDNCPLLPNPSQSDVDNDGVGDACDNCPNLPNPDQKDRDMDFVGDACHRDIDGDDDGVPNSLDNCPMVSNSDQLDTDGDGTGDECDDDMDGDGIPN----YKDNCPLAKNPKQDDFNRNGKGDSCEDDEDVDGVPNGMDNCPNNSMIHHTDFRTLQTIPLDPKGLSQADPNWVVHANGTEIVQTLNSDPGLAVGKDAFGGVDFDGTFYINDDTDDDYAGFVFSYQSSYKYYVVQWKKGTQTYWEPRPFTASAAPGIQIKLVNSTEGPGPMMRNSLWHEGNTDGEARLLWKDPKNIAWKERTSYRWSLVHRPAIGLIRLQMHEGNRLIFDSGNVFDSTLKGGRLGVFCFSQRMIIWSNLQYKCNNRVKPLIYNDLSDYLKTKVELQD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : : ::: . . : : :::: :: : .. . :. :* : . : :: * : .:: : . :* : :.: * *:.* . : . . : ..: :: ::: :: . ::. : . : :* :: ::: : :* :* : *: : :* * . : * *: * :. :* :* .** ** *:* * *::** :.** . * * :***:*. ** ** * .* : . . :* * *:*** * :* * * :*:::* *: *:. : .* . *. :* * : .* * :**** * :**:*.*:*.:**: : * *::*** :********* ** **.** ***.*.: *.**** * * :* ::* * **.**** * * *** ** ** **.*:*.*.: * **** . * .* * * *.******.**::.**:*.* * *:***:*. : *.*.** :: **** * ** ***** ** ******* *.**: : *** *. ** * * * :* ** * * * * * : :* **:*: : ****: **: ***:* :* ****** :* *****:********* **.****:***::* ********:*.**.* .:*** **: ****:. ** * * ****:* *:*. *** :****** *:*. :.******.:*:.**::.**** * *** :* **::::**. *: *** .:*::::***********. ******:*:**: : : : ", "identical_positions": 336, "similar_positions": 221, "identity": "30.71%" }, { "cls_id": "homologset.agr.MGI:1101781", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4V7E1-1", "uniprot_id": "ELF3_RAT", "id": "Q4V7E1-1", "name": "ETS-related transcription factor Elf-3", "aln": "MAATCEISNVFSNYFNAMYSSEDPTLAPAP-LTTFGTEDFVLTLNNQHMSPEGPVGCVGPQTRSQRDRTEPPAVLHLAEKASWTGERPQFWSKTQVLDWISYQVEKNKYDASSIDFSRCDMDGATLCNCALEELRLVFGPLGDQLHAQLRDLTSSSSDELSWIIELLEKDGMTFQEGLGDSGPFDQGSPFAQELLDDGRQASPYYGSSYGPGAPSPGSSDFSTSGTDTPQSSHSSDSGGSDVDLDLTDSKVFPRDGFPDYKKGEPKHGKRKRGRPRKLSKEYWDCLEGKKSKHAPRGTHLWEFIRDILIHPELNEGLMKWENRHEGVFKFLRSEAVAQLWGQKKKNSNMTYEKLSRAMRYYYKREILERVDGRRLVYKFGKNSSGWKEEEVGESQN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UPW2-1", "uniprot_id": "ELF3_MOUSE", "id": "Q3UPW2-1", "name": "ETS-related transcription factor Elf-3", "aln": "MAATCEISNVFSNYFNAMYSSEDPTLAPAP-PTTFGTEDLVLTLNNQQMTLEGP----GPQTRSQRDRTDPLAVLHLAEKASWTSERPQFWSKTQVLEWISYQVEKNKYDASSIDFSRCDMDGATLCSCALEELRLVFGPLGDQLHAQLRDLTSNSSDELSWIIELLEKDGMSFQESLGDSGPFDQGSPFAQELLDDGRQASPYYCSTYGPGAPSPGSSDVSTARTATPQSSHASDSGGSDVDLDLTESKVFPRDGFPDYKKGEPKHGKRKRGRPRKLSKEYWDCLEGKKSKHAPRGTHLWEFIRDILIHPELNEGLMKWENRHEGVFKFLRSEAVAQLWGQKKKNSNMTYEKLSRAMRYYYKREILERVDGRRLVYKFGKNSSGWKEEEVGESRN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P78545-1", "uniprot_id": "ELF3_HUMAN", "id": "P78545-1", "name": "ETS-related transcription factor Elf-3", "aln": "MAATCEISNIFSNYFSAMYSSEDSTLASVPPAATFGADDLVLTLSNPQMSLEGT------------------------EKASWLGEQPQFWSKTQVLDWISYQVEKNKYDASAIDFSRCDMDGATLCNCALEELRLVFGPLGDQLHAQLRDLTSSSSDELSWIIELLEKDGMAFQEAL-DPGPFDQGSPFAQELLDDGQQASPYHPGSCGAGAPSPGSSDVSTAGTGASRSSHSSDSGGSDVDLDPTDGKLFPSDGFRDCKKGDPKHGKRKRGRPRKLSKEYWDCLEGKKSKHAPRGTHLWEFIRDILIHPELNEGLMKWENRHEGVFKFLRSEAVAQLWGQKKKNSNMTYEKLSRAMRYYYKREILERVDGRRLVYKFGKNSSGWKEEEVLQSRN", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*********:*****.*******.***..* :***::*:****.* :*: **. ***** .*:**********:**************:**************.**************************.*****************:***.* *.*****************:*****: .: *.*********.**: * :.:***:*********** *:.*:** *** * ***:******************************************************************************************************************************* :*:*", "identical_positions": 318, "similar_positions": 39, "identity": "80.3%" }, { "cls_id": "homologset.agr.MGI:1194488", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35633-1", "uniprot_id": "VIAAT_MOUSE", "id": "O35633-1", "name": "Vesicular inhibitory amino acid transporter", "aln": "-------------------------------------------------------------------MATLLRSKLT---------NVATSVS------NKSQAKVSGMFARMG---FQAATDEEAVGFAHCDDLDFEHRQGLQMDILKSEGEPCGDEGAEAP--------VEGDIHYQRG-GAPLPPSGSKDQAVGAGGEFGGHDKPKITAWEAG----WNVTNAIQGMFVLGLPYAILHGGYLG-LFLIIFAAVVCCYTGKILIACLYEEN-EDGEVVRVRDSYVAIANACCAPRFPTLGGRVVNVAQIIELVMTCILYVVVSGNLMYNSFPGLP---VSQKSWSIIATAVLLPCAFLKNLKAVSKFSLLCTLAHFVINILVIAYCLSRARDWAWEKVKFYIDVKKFPISIGIIVFSYTSQIFLPSLEGNMQQPSEFHCMMNWTHIAACVLKGLFALVAYLTWADETKEVITDNLPGS------IRAVVNLFLVAKALLSYPLPFFAAVEVLEKSLFQEGSRAFFPACYGGDGRLKSWGLTLRCALVVFTLLMAIYVPHFALLMGLTGSLTGAGLCFLLPSLFHLRLLWRKLLWHQVFFDVAIFVIGGICSVSGFVHSLEGLIEAYRTNAED", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O35458-1", "uniprot_id": "VIAAT_RAT", "id": "O35458-1", "name": "Vesicular inhibitory amino acid transporter", "aln": "-------------------------------------------------------------------MATLLRSKLT---------NVATSVS------NKSQAKVSGMFARMG---FQAATDEEAVGFAHCDDLDFEHRQGLQMDILKSEGEPCGDEGAEPP--------VEGDIHYQRG-GAPLPPSGSKDQAVGAGGEFGGHDKPKITAWEAG----WNVTNAIQGMFVLGLPYAILHGGYLG-LFLIIFAAVVCCYTGKILIACLYEEN-EDGEVVRVRDSYVAIANACCAPRFPTLGGRVVNVAQIIELVMTCILYVVVSGNLMYNSFPGLP---VSQKSWSIIATAVLLPCAFLKNLKAVSKFSLLCTLAHFVINILVIAYCLSRARDWAWEKVKFYIDVKKFPISIGIIVFSYTSQIFLPSLEGNMQQPSEFHCMMNWTHIAACVLKGLFALVAYLTWADETKEVITDNLPGS------IRAVVNIFLVAKALLSYPLPFFAAVEVLEKSLFQEGSRAFFPACYGGDGRLKSWGLTLRCALVVFTLLMAIYVPHFALLMGLTGSLTGAGLCFLLPSLFHLRLLWRKLLWHQVFFDVAIFVIGGICSVSGFVHSLEGLIEAYRTNAED", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H598-1", "uniprot_id": "VIAAT_HUMAN", "id": "Q9H598-1", "name": "Vesicular inhibitory amino acid transporter", "aln": "-------------------------------------------------------------------MATLLRSKLS---------NVATSVS------NKSQAKMSGMFARMG---FQAATDEEAVGFAHCDDLDFEHRQGLQMDILKAEGEPCGDEGAEAP--------VEGDIHYQRGSGAPLPPSGSKDQ-VGGGGEFGGHDKPKITAWEAG----WNVTNAIQGMFVLGLPYAILHGGYLG-LFLIIFAAVVCCYTGKILIACLYEEN-EDGEVVRVRDSYVAIANACCAPRFPTLGGRVVNVAQIIELVMTCILYVVVSGNLMYNSFPGLP---VSQKSWSIIATAVLLPCAFLKNLKAVSKFSLLCTLAHFVINILVIAYCLSRARDWAWEKVKFYIDVKKFPISIGIIVFSYTSQIFLPSLEGNMQQPSEFHCMMNWTHIAACVLKGLFALVAYLTWADETKEVITDNLPGS------IRAVVNIFLVAKALLSYPLPFFAAVEVLEKSLFQEGSRAFFPACYSGDGRLKSWGLTLRCALVVFTLLMAIYVPHFALLMGLTGSLTGAGLCFLLPSLFHLRLLWRKLLWHQVFFDVAIFVIGGICSVSGFVHSLEGLIEAYRTNAED", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1Z9M6-1", "uniprot_id": "A1Z9M6_DROME", "id": "A1Z9M6-1", "name": "Vesicular inhibitory amino acid transporter", "aln": "-------------------------------------------------------------------MSFIAKLKATPLPPLRNILNVAVQTARQQIPERKDYEQPPGSTAQQHHHSQQAQHKAMEAGMDGGDTTEMSSNPFRNAGSWTNDGEGGGDGDGEYRNEYQSTSFNEYDGRYQQTDGFRQGSIASEGSSFVCEGEGGGG--CKIDEFQAA----WNVTNAIQGMFIVSLPFAVLHGGYWA-IVAMVGIAHICCYTGKVLVQCLYEPDPATGQMVRVRDSYVAIAKVCFG---PKLGARAVSIAQLIELLMTCILYVVVCGDLLAGTYPQGS---FDSRSWMLFVGIFLLPMGFLKSLKMVSTLSFWCTMSHIVINAVILGYCLLQIGDWGWSKVRFSIDMENFPISLGVIVFSYTSQIFLPTLEGNMIDRSKFNWMLDWSHIAAAVFKAGFGYICFLTFQNDTQQVITNNLHSQG-----FKGMVNFFLVIKALLSYPLPYYAACELLERNFFRGPPKTKFPTIWNLDGELKVWGLGFRVGVIVSTILMAIFIPHFSILMGFIGSFTGTMLSFIWPCYFHIKIKGHLLDQKEIAKDYLIIGLGVLFGVIGIYDSGNALINAFEIGLPF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P47082-1", "uniprot_id": "AVT1_YEAST", "id": "P47082-1", "name": "Vacuolar amino acid transporter 1", "aln": "MPEQEPLSPNGRKRSEVHYISIPLNRGSAFSPDDSVSQFQSDGFMTRRQSILDHPVGSFKGVNSLSRFATSLRRANSFRNIELNADNERSFFKESNDETYDPDTLAPALDGRRLSVTLNNAGRPRITNLANNDRVSTASMAIHDDDYGSIQNSTIGDSGSILR------PTASLTEMMSGGAGRRFTNNDMDSIVVKRVEGVDGKVVTLLAGQSTAPQTIFNSINVLIGIGLLALPLGLKYAGWVIGLTMLAIFALATFCTAELLSRCLDTDP--------TLISYADLGYAAFG----TKGRALISALFTLDLLGSGVSLVILFGDSLNALFPQYSTTFFKIVSFFIVTPPVFIPLSVLSNISLLGILSTTGTVLVICCCGLYKSSSPGSLVN-PMETSMWPIDLKHLCLSIGLLSACWGGHAVFPNLKTDMRHPDKFKDCLKTTYKITSVTDIGTAVIGFLMFGNLVKDEITKNVLLTEGYPKFVYGLISALMTIIPIAKTPLNARPIVSVLDVLMNVQHIDEAASAIKR--RAAKGLQVFNRIFINVVFVLIAINFPEFDKIIAFLGAGLCFTICLILPCWFYLRLCKTTIKPWERVACHVTICISVVLSTLGVGAAIIS-----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : : * . .. .: : ..: * . : . . :.. ** .. . . * .. . .* : .:. :* *.: *: ::.** .: :.*: : : * *.::* ** . **. :. .. . . * :. ::*: : : *:: *: : :* . .. *: :.. .::* ..*..:. :. :* *: : : . . : .. : **:::: :*:*:: .: .: .:*.*: :* . .:*: :. :: :.* . . : :* : : .:: **.*: . .::. ::. .: . ** . .:*: : .: * : * : * :*:** .*.* ::.: *: :.:: *. *:::: : : : :. : .. *. : . ", "identical_positions": 57, "similar_positions": 184, "identity": "8.99%" }, { "cls_id": "homologset.agr.MGI:1194489", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZID7-1", "uniprot_id": "D3ZID7_RAT", "id": "D3ZID7-1", "name": "Guanylyl cyclase-activating protein 2", "aln": "MGQQFSWEEAEASGEMDVAELQEWYKKFVVECPSGTLFMHEFKRFFKVTGNEEATQYVEGMFRAFDKNGDNTIDFLEYVAALNLVLRGTLEHKLKWTFKIYDKDRNGCIDRLELLDIVEAIYKLKKACRAELDLEQQGQLLTPEEVVDRIFLLVDENGDGQLSLTEFIEGARRDKWVMKMLQMDVNPGGWITQQRRRSAMF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VBV8-1", "uniprot_id": "GUC1B_MOUSE", "id": "Q8VBV8-1", "name": "Guanylyl cyclase-activating protein 2", "aln": "MGQQLSWEEAEAAGEMDVAELQEWYKKFVVECPSGTLFMHEFKRFFKVTGNEEASQYVESMFRAFDKNGDNTIDFLEYVAALNLVLRGSLEHKLKWTFKIYDKDRNGCIDRLELLDIVEAIYKLKKACRAELDLEHQGQLLTPEEVVDRIFLLVDENGDGQLSLTEFIEGARRDKWVMKMLQMDINPGCWITQQRRRSAMF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UMX6-1", "uniprot_id": "GUC1B_HUMAN", "id": "Q9UMX6-1", "name": "Guanylyl cyclase-activating protein 2", "aln": "MGQEFSWEEAEAAGEIDVAELQEWYKKFVMECPSGTLFMHEFKRFFKVTDDEEASQYVEGMFRAFDKNGDNTIDFLEYVAALNLVLRGTLEHKLKWTFKIYDKDGNGCIDRLELLNIVEGIYQLKKACRRELQTE-QGQLLTPEEVVDRIFLLVDENGDGQLSLNEFVEGARRDKWVMKMLQMDMNPSSWLAQQRRKSAMF", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***::*******:**:*************:*******************.:***:****.****************************:*************** **********:***.**:****** **: * ****************************.**:****************:**. *::****:****", "identical_positions": 175, "similar_positions": 21, "identity": "87.06%" }, { "cls_id": "homologset.agr.MGI:1194490", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O08808-1", "uniprot_id": "DIAP1_MOUSE", "id": "O08808-1", "name": "Protein diaphanous homolog 1", "aln": "----------------------------------------------------------------------MEPSGGGLGPGRGTRDKK------------KGRSPDELPATGGDGGKHKKF---------LERFTSMRIKKEKEKPNSAHRNSSASYGD------DPTAQSLQDISDE--QVLVLFEQMLVDMNLNE----EKQQPLREKDIVIKREMVSQYLHTSKAGMNQKESS--RSAMMYIQELRSG-LRDMHLLSCLESLRVSLNNNPVSWVQTFGAEGLASLLDILKRLHDEKEETSGNYDSRNQHEIIR-----------------------------------------------------------------CLKAFMNNKFG-------IKTMLETEEG--ILLLVRAMDPAVPNMMIDAAKLLSALCILPQPEDMNERVLEAMT--ERAEMDEVERFQPLLDGLKSG------------------------------------------------------------------TSIALKVGCLQLINALITPAEELDFRVHIRSELMRLGLHQVLQELREIE----NEDMKVQLCVFDEQGDEDF-FDLKGRLDDIRMEMDDFGEVFQIILNTVKDSKAEPHFLSILQHLLLVRN---DYEARPQYYKLIEECVSQIVLHKNGTDPDFKCRHLQIDIERLVDQMIDKTKVEKSEAKATELEKKLDSELTARHELQVEMKKMENDFEQKLQDLQGEKDALDSEKQ-------------------------------------------------------------------------------------------------QITAQKQDLEAEVSKLTG----------------------------------------------------------------------------------------------------------------------------------------EVAKLSKELEDAKNEMASLS--AVVVAPSVSSSAAVPPAPPLPGDSGTVIPPPPPPPP----LPGGVVPPSPP--LPPGTCIPPPPPLPGGACIPPPPQLPGSAAIPPPPPLPGVASIPPPPPLPGATAIPPPPPLP----------------------------------------------------------------GATAIPPPPP-LPGGTGIPPPPPPLP-------------------------GSVGVPPPPP-LPGGP---------GLPPPPPPFPGAPGIPPPPPGMGVPPPPPFGFGVPAAPVLPFGLTPKK---VYKPEVQLRRPNWSKFVAEDLSQDCFWTKVKEDRFEN----NELFAKLTLAFSAQTKTSKAKKDQEGGEEKKSVQKKKVKELKV-----LDSKTAQNLSIFLG-SFR-MPYQEIKNVILEVNEAVLTESMIQNLIKQMPEPEQLKMLSELKEEYDDLAESE-----QFGVVMGTVPRLRPRLNAILFKLQFSEQVENIKPEIVSVTAACEELRKSENFSSLLELTLLVGNYMNAGSRNAGAFGFNISFLCKLRDTKSADQKMTLLHFLAELCENDHPEVLKFPDELAHVEKASRVSAENLQKSLDQMKKQIADVERDVQNFPAATDE----KDKFVEKMTSFVKDAQEQYNKLRMMHSNMETLYKELGDYFVFDP-KKLSVEEFFMDLHNFRNMFLQAVKENQKRRETEEKMRRAKLAKEKAEKERLEKQQKREQLIDMNAEGDETG-------VMDSLLEALQSG------AAFRRKRGPRQVNRKAGCAVTSLLASELTKDDAMAPGPVKVPKKSEGVPTILEEAKELVGRAS-------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1M775-1", "uniprot_id": "DIAP1_RAT", "id": "F1M775-1", "name": "Protein diaphanous homolog 1", "aln": "----------------------------------------------------------------------MEPSGGGLGPGRGTRDKK------------KGRSPDELPATGGDGGKHKKFTLKRLMADELERFTSMRIKKEKEKPNSAHRNSSASYGD------DPTAQSLQDISDD--QVLVLFEQMLVDMNLNE----EKQQPLREKDIVIKREMVSQYLHTSKAGMNQKESS--RSAMMYIQELRSG-LRDMHLLSCLESLRVSLNNNPVSWVQTFGAEGLASLLDILKRLHDEKEETSGNYDSRNQHEIIR-----------------------------------------------------------------CLKAFMNNKFG-------IKTMLETEEG--ILLLVRAMDPAVPNMMIDAAKLLSALCILPQPEDMNERVLEAMT--ERAEMEEVERFQPLLDGLKSG------------------------------------------------------------------TSIALKVGCLQLINALITPAEELDFRVHIRSELMRLGLHQVLQELREID----NDDMRVQLNVFDEQGDEDF-FDLKGRLDDIRMEMDDFGEVFQIILNTVKDSKAEPHFLSILQHLLLVRN---DYEARPQYYKLIEECVSQIVLHKNGTDPDFKCRHLQIDIEGLVDQMIDKTKVEKSEAKATELEKKLDSELTARHELQVEMKKMENDFEQKLQDLQGEKDALDSEKQ-------------------------------------------------------------------------------------------------QITTQKQDLEAEVSKLTG----------------------------------------------------------------------------------------------------------------------------------------EVAKLSKELEDAKKEMASLS--AVAVAPSVSSSAAVPQAPPLPGTSGTVIPPPPPPP-----LPGGAVPPPPPPPLPAGTGIPPPPPLPGGACISSSPQLFGSTAIPPPPPLPGATAIPPPPPLPGDTAIPPPPPLP----------------------------------------------------------------GXTAIPPPPP-LPGATGVPPPPPPLP-------------------------GSVGVPPPPP-LPGGP---------GLPPPPPPFPGAPGIPPPPPGMGVPPPPPFGFGIPAAPVLPFGLTPKK---VYKPEVQLRRPNWSKFVAEDLSQDCFWTKVKEDRFEN----NELFAKLTLAFSAQTKTSLAKKDQEGGEEKKSVQKKKVKELKV-----LDSKTAQNLSIFLG-SFR-MPYQEIKNVILEVNEAVLTESMIQNLIKQMPEPEQLKMLSELKEEYDDLAESE-----QFGVVMGTVPRLRPRLNAILFKLQFSEQVENIKPEIVSVTAACEELRKSENFSSLLELTLLVGNYMNAGSRNAGAFGFNISFLCKLRDTKSADQKMTLLHFLAELCETDHPDVLKFPDELAHVEKASRVSAENLQKNLDQMKKQIADVERDVQNFPAATDE----KDKFVEKMTSFVKDAQEQYNKLRMMHSNMETLYKELGDYFVFDP-KKLSVEEFFMDLHNFRNMFLQAVKENQKRRETEEKMRRAKLAKEKAEKERLEKQQKREQLIDMNAEGDETG-------VMDSLLEALQSG------AAFRRKRGPRQVNRKAGCAVTSLLASELTKDDAVAASSAKVPKKSEGVTTILEEAKELVGRAS-------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O60610-1", "uniprot_id": "DIAP1_HUMAN", "id": "O60610-1", "name": "Protein diaphanous homolog 1", "aln": "----------------------------------------------------------------------MEPPGGSLGPGRGTRDKK------------KGRSPDELPSAGGDGGKSKKFTLKRLMADELERFTSMRIKKEKEKPNSAHRNSSASYGD------DPTAQSLQDVSDE--QVLVLFEQMLLDMNLNE----EKQQPLREKDIIIKREMVSQYLYTSKAGMSQKESS--KSAMMYIQELRSG-LRDMPLLSCLESLRVSLNNNPVSWVQTFGAEGLASLLDILKRLHDEKEETAGSYDSRNKHEIIR-----------------------------------------------------------------CLKAFMNNKFG-------IKTMLETEEG--ILLLVRAMDPAVPNMMIDAAKLLSALCILPQPEDMNERVLEAMT--ERAEMDEVERFQPLLDGLKSG------------------------------------------------------------------TTIALKVGCLQLINALITPAEELDFRVHIRSELMRLGLHQVLQDLREIE----NEDMRVQLNVFDEQGEEDS-YDLKGRLDDIRMEMDDFNEVFQILLNTVKDSKAEPHFLSILQHLLLVRN---DYEARPQYYKLIEECISQIVLHKNGADPDFKCRHLQIEIEGLIDQMIDKTKVEKSEAKAAELEKKLDSELTARHELQVEMKKMESDFEQKLQDLQGEKDALHSEKQ-------------------------------------------------------------------------------------------------QIATEKQDLEAEVSQLTG----------------------------------------------------------------------------------------------------------------------------------------EVAKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTT-PPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLP----------------------------------------------------------------GSARIPPPPPPLPGSAGIPPPPPPLP-------------------------GEAGMPPPPPPLPGGP---------GIPPPPP-FPGGPGIPPPPPGMGMPPPPPFGFGVPAAPVLPFGLTPKK---LYKPEVQLRRPNWSKLVAEDLSQDCFWTKVKEDRFEN----NELFAKLTLTFSAQTKTSKAKKDQEGGEEKKSVQKKKVKELKV-----LDSKTAQNLSIFLG-SFR-MPYQEIKNVILEVNEAVLTESMIQNLIKQMPEPEQLKMLSELKDEYDDLAESE-----QFGVVMGTVPRLRPRLNAILFKLQFSEQVENIKPEIVSVTAACEELRKSESFSNLLEITLLVGNYMNAGSRNAGAFGFNISFLCKLRDTKSTDQKMTLLHFLAELCENDYPDVLKFPDELAHVEKASRVSAENLQKNLDQMKKQISDVERDVQNFPAATDE----KDKFVEKMTSFVKDAQEQYNKLRMMHSNMETLYKELGEYFLFDP-KKLSVEEFFMDLHNFRNMFLQAVKENQKRRETEEKMRRAKLAKEKAEKERLEKQQKREQLIDMNAEGDETG-------VMDSLLEALQSG------AAFRRKRGPRQANRKAGCAVTSLLASELTKDDAMAAVPAKVSKNSETFPTILEEAKELVGRAS-------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P48608-1", "uniprot_id": "DIA_DROME", "id": "P48608-1", "name": "Protein diaphanous", "aln": "----------------------------------------------------------------------MSRHEKTKSTGGGLLDSL------------FGRPSK---SKGG--------------------TISSGTLAHGGRPVSADN--YVVPGV------EDFEQYIQQLSVA--ELDAKFLEIIEDMNIPK----DKREPLLAKSKEERQKMIMWHLK-GKNSLERSANSRFEKPIDYVEYLQNGEHSTHKVYQCVESLRVALTSNPISWIKEFGVAGIGTIEKLLARSKN-----NASYEK-IEFEAIR-----------------------------------------------------------------CLKAIMNNTWG-------LNVVLNPDQHSVVLLLAQSLDPRKPQTMCEALKLLASFCIVYE-RNGYEKVLRAITTIAATSFKASERFRPIVDALFASDQQ--------------------------------------------------------------DPKRDLACHSLIFINTLTNTPTDLNFRLHLRCEIMRMGLYDRLDEFTKIVEASNNENLQQHFKIFNEIREDDF-EEFVQRFDNVTFNMDDATDCFDVLKNLVTDTTSEPYFLSILQHLLYIRD---DFYFRPAYYQLIEECISQIVFHKGYCDPNFENRNFNIDTSLLLDDIVEKAKAKES--------------------------KRSEEYEKKIEQLES---------------------------------------------------------------------------------------------------------------AKQEAEAKAAHLEE----------------------------------------------------------------------------------------------------------------------------------------KVKLMEAN----------------------------------------------------------------------GVAAPSPNKLP-------------KVNIPMPPPPPGGGGAPPP----------PPPPMP----------------------------------------------------------------GRAGGGPPPP----------PPPPMP-------------------------GRAGGPPPPP-PPPGM---------GGPPPPP----MPGMMRPG---GGPPPPPMMMG-PMVPVLPHGLKPKK---KWDVKNPMKRANWKAIVPAKMSDKAFWVKCQEDKLAQ----DDFLAELAVKFSSKP----VKKEQKDAVDKPTTLTKKNVDLRV-----LDSKTAQNLAIMLGGSLKHLSYEQIKICLLRCDTDILSSNILQQLIQYLPPPEHLKRLQEIKAKGEPLPPIE-----QFAATIGEIKRLSPRLHNLNFKLTYADMVQDIKPDIVAGTAACEEIRNSKKFSKILELILLLGNYMNSGSKNEAAFGFEISYLTKLSNTKDADNKQTLLHYLADLVEKKFPDALNFYDDLSHVNKASRVNMDAIQKAMRQMNSAVKNLETDLQNNKVPQCD----DDKFSEVMGKFAEECRQQVDVLGKMQLQMEKLYKDLSEYYAFDP-SKYTMEEFFADIKTFKDAFQAAHNDNVRVREELEKKRRLQEAREQSAREQQERQQRKKAVVDMDAPQTQEG-------VMDSLLEALQTG------SAFGQRNRQARRQRPAGAERRAQLS----------RSRSRTRVTNGQLMTREMILNEVLGSA--------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P41832-1", "uniprot_id": "BNI1_YEAST", "id": "P41832-1", "name": "Protein BNI1", "aln": "MLKNSGSKHSNSKESHSNSSSGIFQNLKRLANSNATNSNTGSPTYASQQQHSPVGNEVSTSPASSSSFRKLNAPSRSTSTEARPLNKKSTLNTQNLSQYMNGKLSGDVPVSSQHARSHSMQSKYSYSKRNSSQASNKLTRQHTGQSHSASSLLSQGSLTNLSKFTTPDGKIYLEMPSDPYEVEVLFEDIMYKRNIFQSLSEDKQEALMGYSIEKKWLIVKQDLQNELKKMRANTTSSSTASRTSMASDHHPILTANSSLSSPKSVLMTSASSPTSTVYSNSLNHSTTLSSVGTSTSKGKKLVSGSLKKQPSLNNIYRGGAENNTSASTLPGDRTNRPPIHYVQRILADKLTSDEMKDLWVTLRTEQLDWVDAFIDHQGHIAMANVLMNSIYKTAPRENLTKELLEKENSFFKCFRVLSMLSQGLYEFSTHRLMTDTVAEGLFSTKLATRKMATEIFVCMLEKKNKSRFEAVLTSLDKKFRIGQNLHMIQNFKKMPQYFSHLTLESHLKIIQAWLFAVEQTLDGRGKMGSLVGASDEFKNGGGENAILEYCQWTMVFINHLCSCSDNINQRMLLRTKLENCGILRIMNKIKLLD----YDKVIDQIELYDNNKLDDFNVKLEANNKAFNVDLHDPLSLLKNLWDICKGTENEKLLVSLVQHLFLSSSKLIEENQNSSKLTKQLKLMDSLVTNVSVASTSDEETNMNMAIQRLYDAMQTDEVARRAILESRALTKKLEEIQAERDSLSEKLSKAEHGLVGQLEDELHERDRILAKNQRVMQQLEAELEELKKKHLLEKHQQEVELRKMLTILNSRPEESFNKNEGTRGMNSSLNSSEKANIQKVLQDGLSRAKKDYKDDSKKFGMTLQPNKRLKMLRMQMENIENEARQLEMTNFAEFEKDRLEPPIHIKKPKVKKMKNKDRKPLVKPQEADVNKLNDLRRALAEIQMESNDISKFNVEERVNELFNEKKSLALKRLKELETKYKGFGIDFNVDEIMDSPKKNTGDVETEEDANYASLDPKTYQKKLDEINRITDQLLDIQTQTEHEIQVEEDGESDLSSSSSDDESEEIYQDASPTQELRSEHSELSSGSGPGSFLDALSQKYGTGQNVTASAAFGENNNGSGIGPLHSKVEKTFMNRLRKSTVSSAPYLEELTQKVNKVEPYEQNEDEGLDKKSLPENSTASAASAFDKAEKDMRQHVENGKQGRVVNHEEDKTADFSAVSKLNNTDGAEDLSTQSSVLSSQPPPPPPPPPPVPAKLFGESLEKEKKSEDDTVKQETTGDSPAPPPPPPPPPPPPMALFGKPKGETPPPP---PLPSVLSSSTDGVIPPAPPMMPASQIKSAVTSPLLPQSPSLFEKYPRPHKKLKQLHWEKLDCTDNSIWGTGKAEKFADDLYEKGVLADLEKAFAAREIKSLASKRKEDLQKITFLSRDISQQFGINLHMYSSLSVADLVKKILNCDRDFLQTPSVVEFLSKSEIIEVSVNLARNYAPYSTDWEGVRNLEDAKPPEKDPNDLQRADQIYLQLMVNLESYWGSRMRALTVVTSYEREYNELLAKLRKVDKAVSALQESDNLRNVFNVILAVGNFMN--DTSKQAQGFKLSTLQRLTFIKDTTNSMTFLNYVEKIVRLNYPSFNDFLSELEPVLDVVKVSIEQLVNDCKDFSQSIVNVERSVEIGNLSDSSKFHPLDKVLIKTLPVLPEARKKGDLLEDEVKLTIMEFESLMHTYGEDSGDKFAKISFFKKFADFINEYKKAQAQNLAAEEEERLYIKHKKIVEEQQKRAQEKEKQKENSNSPSSEGNEEDEAEDRRAVMDKLLEQLKNAGPAKSDPSSARKRALVRKKYLSEKDNAPQLLNDLDTEEGSILYSPEAMDPTADTVIHAESPTPLATRGVMNTSEDLPSPSKTSALEDQEEISDRARMLLKELRGSDTPVKQNSILDEHLEKLRARKERSIGEASTGNRLSFK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. .. :. *: . . . . :. ** : ::. :: . * ::: . *: : :*::.* . : :: * : . .* . : : .. :*: :: ..* * : . :: .: . .. .. . : * :.:**. : : :*: :: : . :: . : : :.. . : : : . . .**..:: .* . : :** * . . ::: *: :* :: . *: ::.: : :.: :: :::: :* .: . . . .::.* . :. : : ..: * ::*::***: . : .. : :..:* : . ... : :::: . * * : . ...: * . :::: :: * :. :* :: : : * ... : .. . ..* * * . .. **** * ***** * * .**** *.: . **.**: . ..:. * *:. . :: : . ::..:* . : ::: : . .:*.* *::: ..* ::. . . :: : . ..*: : :*. . : .: : . : :: .: :: . * :: *.: * . : : :. .*:. : . : ::: ..: * . :::*..: .:::: * :**:** . . * **::* * :* *.: :. *:*::: .: . ..*. .* .:* * .. :*. : : : ::.. : ::* .:: . . **. . :.::: : * ::.* . : *. .* : .** .: * : : * :* .* . : : *: :. *:::::: . .: : . ***.*** *:.. .: ::. : : : . * .. . . : . ", "identical_positions": 120, "similar_positions": 398, "identity": "6.12%" }, { "cls_id": "homologset.agr.MGI:1194491", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97592-1", "uniprot_id": "MCPT4_RAT", "id": "P97592-1", "name": "Mast cell protease 4", "aln": "-----MKALLFLMALLLPSGAGAEEIIGGVESIPHSRPYMALLKIVTEEGHVTFCGGFLISLQFVLTAAHCHGR----EITVTLGAHDMSKRESTQQKIKVVKQIFPLKYNLFSNFRDIMLLKLEQKAVLTPSVNVIPLPQSSDIIKPGTMCLAAGWGQTGVKEPNSNTLREVMLRIMEMKACKDYRHYDNRFQICVGIPQMLKLAYK-GDSGGPLVCAGVAHGIVSHGPGR----GIPPIIFTRISSYVSWINRVIRGN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35164-1", "uniprot_id": "MCPT9_MOUSE", "id": "O35164-1", "name": "Mast cell protease 9", "aln": "-----MQALLFLMALLLPSRAGAEEIIGGVESEPHSRPYMAYVNTFSKKGYVAICGGFLIAPQFVMTAAHCSGR----RMTVTLGAHNVRKRECTQQKIKVEKYILPPNYNVSSKFNDIVLLKLKKQANLTSAVDVVPLPGPSDFAKPGTMCWAAGWGRTGVKKSISHTLREVELKIVGEKACKIFRHYKDSLQICVGSSTKVASVYM-GDSGGPLLCAGVAHGIVSSGRGN----AKPPAIFTRISPHVPWINRVIKGE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M1PUX6-1", "uniprot_id": "A0A8M1PUX6_DANRE", "id": "A0A8M1PUX6-1", "name": "trypsin", "aln": "MQYIMLLCVFLLLSLFSLSGGLESGIVGGREAKHHSRPYMASLQKKRN----HVCGGMLIKEDYVLTSAHCWNETDKYSLQIVLGAHNISQKENSQQIIQVEKYIKHRKF-------DIMLLKLRTKAVLNHFVDIINLPKHEISILAPLECSIAGWGMKRPGEGASNVLRVVNLQLESNAKCKSKWQTHFNFKNMVCTVSDGKKAFCQGDSGSPLLCNSELYGMAAYTYPKNCTFKEYPEVYMKVSAFLPWIKKNIQ--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .:::*::*: * . . *:** *: ******* :: : .***:** ::*:*:*** .. : :.****:: ::* :** *:* * * :: **:****. :* *. *::: ** . . * **** . : *:.** * *:: ** : . :: * .: ****.**:* . :*:.: . * :: ::*..:.**:: *: ", "identical_positions": 72, "similar_positions": 74, "identity": "27.69%" }, { "cls_id": "homologset.agr.MGI:1194492", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q925G1-1", "uniprot_id": "HDGR2_RAT", "id": "Q925G1-1", "name": "Hepatoma-derived growth factor-related protein 2", "aln": "-----MPHAFKPGDLVFAKMKGYPHWPARIDDIADGAVKPPPNKYPIFFFGTHETAFLGPKDLFPYDKCKDKYG--KPNKRKGFNEGLWEIQNNPHASYSAPLPVSSSDSEAPEADLGGGSDADKEKEARRVMTVTAVTTTATSGRTESDSDSDKNSDHSGLKRKTPVLKMSVSKRARKASSDLD-QASVSPSEED-SESP-SESEKTSDQDFTPEKKTIARAPRRAPLGGRKKKKVPSASDSDS---------RADSDGAKEEPVVTAQPSPSSSSSSSSSSASDSDVSIKKPPRGRKPAEKPPPKPRGRRSK--PERPPSTSSSDSDSDSGEVDRISEWKRRDEERRRELEARRRREQEEELRRLREQEREEKERRKE----RAERG-------GSSGEEL-EDEEPVKKRSRKARG-RGTPSSSDSEPEGELGK--EGKKLAKKSQLQGSESARKPGQKEKRGRPDEKPRARPVKVERTRKRSEGLSLDRKGEKKKEPSVEERLQKLHSEIKFALKVDNPDVRRCLSALEELGTLQVTSQILQKNTDVVATLKKIRRYKANKDVMAKAAEVYTRLKSRVLGPKVEALQKVNKAGAEKERADGEKV-EEQPGEQAPRELAEDEPSTDRSAPVNGEAASQKGENTEDGAQEDGQDLEDGPRGGSSEELHDSPQDSSDPARPGNEHQDHERMQLASESADDDDEDS---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UMU9-1", "uniprot_id": "HDGR2_MOUSE", "id": "Q3UMU9-1", "name": "Hepatoma-derived growth factor-related protein 2", "aln": "-----MPHAFKPGDLVFAKMKGYPHWPARIDDIADGAVKPPPNKYPIFFFGTHETAFLGPKDLFPYDKCKDKYG--KPNKRKGFNEGLWEIQNNPHASYSAPPPVSSSDSEAPEADLGCGSDVDKDKESRRVMTVTAVTTTATSDRMESDSDSDKSSDHSGLKRKTPVLKVSVSKRARRASSDLD-QASVSPSEED-SESP-SESEKTSDQDFTPEKKTAARPPRRGPLGGRKKKKVPSASDSDS---------KADSDGAKEEPVVTAQPSPSSSSSSSSSSSSDSDVSVKKPPRGRKPAEKPPPKPRGRRPK--PERPPSTSSSDSDSDSGEVDRISEWKRRDEERRRELEARRRREQEEELRRLREQEREEKERRKE----RAERG-------GSSGEEL-EDEEPVKKRSRKARG-RGTPSSSDSEPEGELGK--EGKKLAKKSQLPGSESARKPGQKEKRGRPDEKPRARPVKVERTRKRSEGLSLERKGEKKKEPSVEERLQKLHSEIKFALKVDNPDVRKCLSALEELGTLQVTSQILQKNTDVVATLKKIRRYKANKDVMAKAAEVYTRLKSRVLGPKVEALQKVNKAGAEKERADNEKL-EEQPGEQAPRELAEDEPSTDRSAPVNGEATSQKGENMEDRAQEDGQDSEDGPRGGSSEELHDSPRDNSDPAKPGNERQDHERTRLASESANDDNEDS---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7Z4V5-1", "uniprot_id": "HDGR2_HUMAN", "id": "Q7Z4V5-1", "name": "Hepatoma-derived growth factor-related protein 2", "aln": "-----MPHAFKPGDLVFAKMKGYPHWPARIDDIADGAVKPPPNKYPIFFFGTHETAFLGPKDLFPYDKCKDKYG--KPNKRKGFNEGLWEIQNNPHASYSAPPPVSSSDSEAPEANPADGSDADEDDEDRGVMAVTAVTATAASDRMESDSDSDKSSDNSGLKRKTPALKMSVSKRARKASSDLD-QASVSPSEEENSESS-SESEKTSDQDFTPEKKAAVRAPRRGPLGGRKKKKAPSASDSDS---------KADSDGAKPEPVAMAR---SASSSSSSSSSSDSDVSVKKPPRGRKPAEKPLPKPRGRKPK--PERPPSSSSSDSDSD--EVDRISEWKRRDEARRRELEARRRREQEEELRRLREQEKEEKERRRE----RADRGEAERGSGGSSGDELREDDEPVKKRGRKGRG-RGPPSSSDSEPEAELER--EAKKSAKKPQSSSTEPARKPGQKEKRVRPEEKQQAKPVKVERTRKRSEGFSMDRKVEKKKEPSVEEKLQKLHSEIKFALKVDSPDVKRCLNALEELGTLQVTSQILQKNTDVVATLKKIRRYKANKDVMEKAAEVYTRLKSRVLGPKIEAVQKVNKAGMEKEKAEEKLAGEELAGEEAPQEKAEDKPSTDLSAPVNGEATSQKGESAEDKEHEEGRDSEEGPRCGSSEDLHDSVREGPDLDRPGSDRQERERARGDSEALDEES------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5XXA7-1", "uniprot_id": "HDGR2_DANRE", "id": "Q5XXA7-1", "name": "Hepatoma-derived growth factor-related protein 2", "aln": "-----MPHNFRPGDLVFAKMKGYPHWPARIEDVADGAVKPPPNKIPIFFFGTHETAFLAPKDLFAYEKNQERFG--KPNKRKGFNEGLWEIQNNPHASYNTPAAASSSDSED--NQPAAASDAEEEEE-------AVVPRKAETGSDDSDSGSE-DQKKPAVKRKAPALKRPPVKKARASSSDRDGEESGSPSEPEPSPSSDSDSGKNSDQDFTPQKESGGRGGKK-PAGRGRRKKASSGSDSDSGSQSDQKAARSDSEDEKPRPAASGSESQSGSKSDSDSEPPPPPPPTRKAPQGRKKAEKPPPKPRARKPKPAPERAPS-SSSDSDSDS-DTDRVSEWKKRDEERRKELEERRKREEAEELRRLREREKEEEEKRKKDKETKVRRGSS---SSGSSSSDDEVDDHPLKKSKKPPPPPIPAPSDSDSPPPSELKKKKESQKGRQKKEKEVKEKKERPVKEKKPQRSEEKHKAKPKAEKPKRKPVR--PPEKKVEKKKEPSPEEKLQKLHTDIKFALKVDNPDIEKCLQALDELSSVQVTTHILQKNADVIATLKKIRRYKASNAVMEKATAVYNKLKLQFIG-KIETGKPK-------------------PNEKNQEE--QDAQNTDDSKPVNGESEGERKDVSESESNSKPTDQDNPDENKSPNGIRPDPDEPADQLNDSTEADPTADADVKEDSREQDEQMSSES", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VAA9-1", "uniprot_id": "Q9VAA9_DROME", "id": "Q9VAA9-1", "name": "", "aln": "MGKEKAAASYSIGDLVFAKVKGYPPWPAKITKSNN------NKKYNVYFYGTGETANIKLEDLFPYASNKERFATEKIMKRAKFIEAIDQIESALRGEDSAPIDLLDG------------------------------AEPVAPPTTGDGVKTEEPKPEPGPEPATAAPVAAAAEKPKKS-------------------------------------------------GTRKTKAPPRHVDGDS---------------------------------EAGAELAPPPAKRRVPTEGLATAAAIPAAPAAATPT---------SSKKSVKKSKPTAAVTPIQKRS----RPVNNIRNEMLMVYMPTAKCLGIVINYKKPE-------------------------------------------SFESAAAEEAWMEN---ARKEALELKLKLESGQINPESMPDRIVVEPTRSEIPKQEALR-------FIEELIEHEDALFMERDFIQLSQQLRECLGLRRANVGKCLEILEQFKEVEFTKLMLLRNPECVDIMRRLRRYVGNLELWKMDLSDEVEFKERAQTIRKVS---------------------------------------------SGIYDGFKSLFNPEPESEDNFWIDFCEKVKIYKTYTKNINENLRVGMNERGYNSLVLAKEAAASAGSAPQ-----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : *******:**** ***:* . : :* ::*:** *** : :***.* . ::::. * ** * *.: :*:. :.. .:* .. . . . .. :: . ... : :.. . ::.: : * : * . *.** .:.:. . . : ...* * . * . .. **..* .. . :: ::*. : :: *.. : : : :: : . .* : . : . .:* : : . .* . . : . * :. *::. *. : :* ::: .* : .:: :**. *::: ::.*. :* :*.: : ::::*** .. : .:* : : : .* . : . .. : . : . : : : . ", "identical_positions": 65, "similar_positions": 163, "identity": "9.17%" }, { "cls_id": "homologset.agr.MGI:1194494", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VHK7-1", "uniprot_id": "HDGF_RAT", "id": "Q8VHK7-1", "name": "Hepatoma-derived growth factor", "aln": "MSRSNRQKEYKCGDLVFAKMKGYPHWPARIDEMPEAAVKSTANKYQVFFFGTHETAFLGPKDLFPYEESKEKFG--KPNKRKGFSEGLWEIENNPTVKASG------------YQSSQKKSCAEEPEVEP--------------EAHEGDGDKKGNAE----GSSDEEGKLVIDEPAKEKNEKGMLKRRAGDMLEDSPKRPKESGDHEEEEKEIAALE--GERPLPVEMEKNS----------------TPSEPDSGQGPPPEEEEGE---EEAAKEEAEAQG--------------------VRDHESL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P51859-1", "uniprot_id": "HDGF_MOUSE", "id": "P51859-1", "name": "Hepatoma-derived growth factor", "aln": "MSRSNRQKEYKCGDLVFAKMKGYPHWPARIDEMPEAAVKSTANKYQVFFFGTHETAFLGPKDLFPYEESKEKFG--KPNKRKGFSEGLWEIENNPTVKASG------------YQSSQKKSCAAEPEVEP--------------EAHEGDGDKKGSAE----GSSDEEGKLVIDEPAKEKNEKGTLKRRAGDVLEDSPKRPKESGDHEEEDKEIAALE--GERPLPVEVEKNS----------------TPSEPDSGQGPPAEEEEGE---EEAAKEEAEAQG--------------------VRDHESL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P51858-1", "uniprot_id": "HDGF_HUMAN", "id": "P51858-1", "name": "Hepatoma-derived growth factor", "aln": "MSRSNRQKEYKCGDLVFAKMKGYPHWPARIDEMPEAAVKSTANKYQVFFFGTHETAFLGPKDLFPYEESKEKFG--KPNKRKGFSEGLWEIENNPTVKASG------------YQSSQKKSCVEEPEPEP--------------EAAEGDGDKKGNAE----GSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAATLE--VERPLPMEVEKNS----------------TPSEPGSGRGPPQEEEEEEDEEEEATKEDAEAPG--------------------IRDHESL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VAA9-1", "uniprot_id": "Q9VAA9_DROME", "id": "Q9VAA9-1", "name": "", "aln": "MGKEKAAASYSIGDLVFAKVKGYPPWPAKITKS------NNNKKYNVYFYGTGETANIKLEDLFPYASNKERFATEKIMKRAKFIEAIDQIESALRGEDSAPIDLLDGAEPVAPPTTGDGVKTEEPKPEPGPEPATAAPVAAAAEKPKKSGTRKTKAPPRHVDGDSEAGAELAPPPAKRRVPTEGLATAAAIPAAPAAATPTSSKKSVKKSKPTAAVTPIQKRSRPVNNIRNEMLMVYMPTAKCLGIVINYKKPESFESAAAEEAWMENARKEALELKLKLESGQINPESMPDRIVVEPTRSEIPKQEALRFIEELIEHEDALFMERDFIQLSQQLRECLGLRRANVGKCLEILEQFKEVEFTKLMLLRNPECVDIMRRLRRYVGNLELWKMDLSDEVEFKERAQTIRKVSSGIYDGFKSLFNPEPESEDNFWIDFCEKVKIYKTYTKNINENLRVGMNERGYNSLVLAKEAAASAGSAPQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.:.: .*. *******:**** ***:* : .. :**:*:*:** *** : :***** ..**:*. * ** * *.: :**. : *. :: . . **: ** * : .* :* .* ....* * : ***.: . * *. :. *..: . :.* *:: :*. *:: :*. . .:* * .... ** * :** : . : . : .:*:* ", "identical_positions": 72, "similar_positions": 77, "identity": "14.97%" }, { "cls_id": "homologset.agr.MGI:1194495", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AM80-1", "uniprot_id": "A0A8I6AM80_RAT", "id": "A0A8I6AM80-1", "name": "", "aln": "-MEANYSVPLNVSEVVVYDSTISRVLWILSMVVLSITFVLGVLGNGLVIWVAGFRMVHTVTTTCYLNLALADFSFTATLPFFVISTAMKEKWPFGWFLCKLVHIVVDINLFGSVFLIALIALDRCICVLHPVWAQNHRTVSLARKVVVGPWILALILTLPIFVFMTTVRVPGGNVYCTFNYASWGKTVEEVLDVANTCETVRGTIRFVIGFTMPMSIVAICYGLIAVKIHRRALVNSSRPLRVLTAVVVSFFICWFPFQLVALLGTIWFKELLFNTRYGILKMWVNPTSSLAYFNSCLNPMLYVFMGQDFRERLIHSLPSSLERALSE-----DCGQTSDTGTNSALPPADIEIKAI-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O08790-1", "uniprot_id": "FPRS1_MOUSE", "id": "O08790-1", "name": "Formyl peptide receptor-related sequence 1", "aln": "-METNYSIPLNGSDVVIYDSTISRVLWILSMVVVSITFFLGVLGNGLVIWVAGFRMPHTVTTIWYLNLALADFSFTATLPFLLVEMAMKEKWPFGWFLCKLVHIAVDVNLFGSVFLIAVIALDRCICVLHPVWAQNHRTVSLARNVVVGSWIFALILTLPLFLFLTTVRDARGDVHCRLSFVSWGNSVEERLNTAITFVTTRGIIRFIVSFSLPMSFVAICYGLITTKIHKKAFVNSSRPFRVLTGVVASFFICWFPFQLVALLGTVWLKEMQFSGSYKIIGRLVNPTSSLAFFNSCLNPILYVFMGQDFQERLIHSLSSRLQRALSE-----DSGHISDTRTNLASLPEDIEIKAI-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P25090-1", "uniprot_id": "FPR2_HUMAN", "id": "P25090-1", "name": "N-formyl peptide receptor 2", "aln": "-METNFSTPLNEYEEVSYESAGYTVLRILPLVVLGVTFVLGVLGNGLVIWVAGFRMTRTVTTICYLNLALADFSFTATLPFLIVSMAMGEKWPFGWFLCKLIHIVVDINLFGSVFLIGFIALDRCICVLHPVWAQNHRTVSLAMKVIVGPWILALVLTLPVFLFLTTVTIPNGDTYCTFNFASWGGTPEERLKVAITMLTARGIIRFVIGFSLPMSIVAICYGLIAAKIHKKGMIKSSRPLRVLTAVVASFFICWFPFQLVALLGTVWLKEMLFYGKYKIIDILVNPTSSLAFFNSCLNPMLYVFVGQDFRERLIHSLPTSLERALSE-----DSAPTNDTAANSASPPAETELQAM-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P25089-1", "uniprot_id": "FPR3_HUMAN", "id": "P25089-1", "name": "N-formyl peptide receptor 3", "aln": "-METNFSIPLNETEEVLPEPAGHTVLWIFSLLVHGVTFVFGVLGNGLVIWVAGFRMTRTVNTICYLNLALADFSFSAILPFRMVSVAMREKWPFGSFLCKLVHVMIDINLFVSVYLITIIALDRCICVLHPAWAQNHRTMSLAKRVMTGLWIFTIVLTLPNFIFWTTISTTNGDTYCIFNFAFWGDTAVERLNVFITMAKVFLILHFIIGFSVPMSIITVCYGIIAAKIHRNHMIKSSRPLRVFAAVVASFFICWFPYELIGILMAVWLKEMLLNGKYKIILVLINPTSSLAFFNSCLNPILYVFMGRNFQERLIRSLPTSLERALTEVP---DSAQTSNTDTTSASPPEETELQAM-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PB91-1", "uniprot_id": "A0A8M9PB91_DANRE", "id": "A0A8M9PB91-1", "name": "", "aln": "-MTNNTTFSFLSNSKISIHYEKT----TVDMVFYTIVILLGTTGNSVVIWVAGFHMKSNVTKVWLVNLAVADLIFCLTRISSLISKVFFDYWPFGVFLCKFNGFIKYANMFCSVFLLAVISVDRALCIWHPFFTRERRTVCAARVVSVGVWIVAVIFSSPYFVYRQVFPGKNNLSHCSLKVNGSSETG-------ISTKYVYYFIRFICGFLLPFLIIFICYTLAAIGIRRSRLSRKAKPLRILAVLVCAFFLCWAPYHFLGLVK-------LVNKDNEVVKIGWNMASNLAYFNSCINPILYFFMGLDVSRRCNQSLSGIFRRALMEEGQSLSQQGIGEDISNSFLKTIGVECETKV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M6YSE5-1", "uniprot_id": "A0A8M6YSE5_DANRE", "id": "A0A8M6YSE5-1", "name": "", "aln": "MENSSFGLKNLTGNSTDKNAVEDKGFKIFLACIFFSTVSVGLIGNGLVIFLAGCRMKMTFNSIWFLNLAIADFIF---ILFSITNASLTLSKQHSVVKEYFLFIATSINLFASIWSLVVISLDRCLCTWMAVWAQNNRTLRKARIICIIIWVSSIGYILPYFTVFNITG------------------------------TILVTYGFIVVFLIPFLIIASSYIAIGVKINRLKKRKQLRSYRLIITVILTFFICSFPHN-VCWIWMVWAKNNNWTLTDQFWKLFV-FTFYLMNLNSSLNPFLYVFMCDDFKKKLKQSLVLVLETAFAE-----DHLDIKEMRHTKMINRQNKPHLNC-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . . . .. .* **.:**::** :* .... :***:**: * : . : .. . : . *:* *:: : .*::**.:* . ::::.**: * : *: :: * * *: * :*: :: .* *.: .. :. *:: :: :**:* *.. : : . : * :**.:**:**.*: :. .: :** :. *: * . : . ", "identical_positions": 49, "similar_positions": 89, "identity": "13.69%" }, { "cls_id": "homologset.agr.MGI:1194497", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q15583-1", "uniprot_id": "TGIF1_HUMAN", "id": "Q15583-1", "name": "Homeobox protein TGIF1", "aln": "MVLAQSRVSAGVGSPHCSGSGGGGSDSFPWPASHPGNPQCSFSTAFLASPRLSRGTLAYLPPAPWSSLATPSALLGSSCAPPPPPARCPQPRALSPELGTKAGPRRPHRWELPRSPSQGAQGPAPRRRLLETMKGIVAASGSETEDEDSMDIPLDLSSSAGSGKRRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLSTLQVCNWFINARRRLLPDMLRKDGKDPNQFTISRRGAK------------------------------ISETSSVESVMGIKNFMPALEETPFHSCTAGPN----------------------------------------------------------------------------------------PTLGRPLSPKPS------------------------------------SPGSVLARPSVICHTTVTALKDVPFSLCQSVGVGQNTDIQQIAAKNF--TDTSLMYPEDTCKSGPSTNTQ-SGLFNTPPPTPPDLNQDFSGFQ---------------------------LLVDVALKRAAEMELQAKLTA------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P70284-1", "uniprot_id": "TGIF1_MOUSE", "id": "P70284-1", "name": "Homeobox protein TGIF1", "aln": "---------------------------------------------------------------------------------------------------------------------------------MKSKKGLVAASGSDSEDEDSMDSPLDLSSSAASGKRRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLSTLQVCNWFINARRRLLPDMLRKDGKDPNQFTISRRGAK------------------------------ISEASSIEAAMGIKNFMPTLEESPFHSCVVGPN----------------------------------------------------------------------------------------PTLGRPVSPKPP------------------------------------SPGSILARPSVICHTTVTALKDGPFSLCQPIGVGQSTDVPQIAPSNF--TDTSLVYPEDTCKSGPSPNPQ-SGLFNTPPPTPPDLNQDFSGFQ---------------------------LLVDVALKRAAEMELQAKLTA------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZTL5-1", "uniprot_id": "A0A8I5ZTL5_RAT", "id": "A0A8I5ZTL5-1", "name": "", "aln": "------------------------------------------MTLLLGSATLERG---------------------------------------TGDLG-------------------------PRTRAVQLEGVVAAASGSDSEDEDSMDSPLDLSSSAASGKRRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLSTLQVCNWFINARRRLLPDMLRKDGKDPNQFTISRRGAK------------------------------ISEASSIEAAMGIKNFMPTLEESPFHSCVVGPN----------------------------------------------------------------------------------------PTLGRPVSPKPP------------------------------------SPGPILARPSVICHTTVTALKDGPFSLCQAVSVGHSTDVQQVAPSNF--TDASLRYPEDTCKSGPSPNPQ-SGLFNTPPPTPPDLNQDFSGFQ---------------------------LLVDVALKQAAEMELQAKLTA------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A1Z916-1", "uniprot_id": "A1Z916_DROME", "id": "A1Z916-1", "name": "", "aln": "---MISPEQEEVNMVLDRHVRQNIQDMMHEAHVQASLLENEGRGRFHSDSSLDQDS--------------------------------------------------------------------LHADVIVEEDQSTEHGANQVQNYHDMMVDSEHHIDINGSLRKRRGNLPKTSVKILKRWLYEHRYNAYPSDAEKFTLSQEANLTVLQVCNWFINARRRILPEMIRREGNDPLHFTISRRGKKVSPNCSRSSALGANLTGPNPAHGSPASEVVVGATEEVDGAGEIHEGIANVLTN-FEQYVQGPNGQMVKMEPEYEDSVIYSWQQAIANNPMGFQSLHSSLQATMIDKIKNYQMRKAAAIGGSAVGSGGAGGSSSNSSPATSILPYSLFGQLPPEFDDEEKPRPPKRVRTRTVAAKSPRENAKQAKQKTGNKQETMYCYKDSYGGIVVSPRSEGEESAQGYESCGPNSEEEVRFETSHDWQSVIKTVFGTEEVSTSAGNNPGTSGSKGSVQNTAIWNRNQTAKRDVNQQLTDFESELNRIQASEIQTIDPTNSNQQDIGDNLQADEVFTGAEAEAGQSQLSAMSQGTSPDERAKYKCLYYLVETAMAVRQNDDVQDDDFVYMGD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A1Z913-1", "uniprot_id": "A1Z913_DROME", "id": "A1Z913-1", "name": "", "aln": "---MISPEQEEVNMVLDRHVRQNIKDLMHEAHVHASLLNNEGRDRFHSDSSLDQDS--------------------------------------------------------------------LHA--VVGNDLSTEQGANQVQNYHDMMVDSEHHVDINGSLRKRRGNLPKSSVKILKRWLYEHRYNAYPSDAEKFTLSQEANLTVLQVCNWFINARRRILPEMIRREGNDPLHFTISRRGKK-----------------------------VVGATEEVDGAGEIHEGIANVLTN-FEQYVQGPNGQMVKMEPEYEDSVIYSWQQAIANNPMGFQSLHSSLQATMIDKIKNYQMRKAAAIGGSAVGSGGAGGSSSNSSPATSILPYSLFGQLPPEFDDEEKPRPPKRVRTRTVAAKSPRENAKQAKQKTGNKQETMYCYKDSYGGIVVSPRSEGEESAQGYESCGPNSEEEVRFETSHDWQSVIKTVFGTEEVSTSAGNNPGTSGSKASVQNTAIWNRNQTAKRDVNQQLTDFESELNIIQASEIQTIDPTNSNQQDIGDNLQADEVFTGAEAEAGQSQLSALSQGTSSDEEGKYKCLYYLVETAMAVRQNDDVQDDDFVYMGD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . ...: :: ..* : . .. *:******* **:**: ************: ** ***:::*:.*************:**:*:*::*:** :******* * :. :..::.. *:: :. : . *.. . *** * :. .*:*. * * ::. * . :. . :. . : : . . * .: . * :.* ::. .**.. . * :.::* .: *:**:::.*: * .* .:. * *::*:* ", "identical_positions": 87, "similar_positions": 98, "identity": "13.88%" }, { "cls_id": "homologset.agr.MGI:1194498", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0RBT0-1", "uniprot_id": "M0RBT0_RAT", "id": "M0RBT0-1", "name": "Serine/threonine-protein kinase haspin", "aln": "-MAASHRRSGTRLFRTYAARGVRRSQRQPDSLAVKWFQP-------------PNPKLSFSSSLSD----SNLSPAVASDNPEDPDFPGSPVGPRRRRPRGCDSPD------------------LTHTKR---VLRLRPRPPQKCSTPCS-------------------RLRPPPFLSCSPGCLGSDLN-----------------VCIQSRNSNELGTSASLFSPPAS--PGAPDS------------LNADSTVPGSLH---------FRVASLGEASLPCPQEAATEEGKYTRSAPQAEASFRSSLSSRVDPRTTEAKELGTDGENVKESCCER-QQTGNRLTDPDLASLGKRTAT----CKKVVSRGVDQIDYGESSARKDLRVPGKISRPKRTEPLRKRKQQE-----------------------------------------------------------------------------AVGTSPLRYHQSKKKR---KDSFCSRDLNTSCKDS--------------------------------------------WTKTRASFGFHKKKIIT----------------------------NVAEVCSR-SITSSLSRSFQSECSIS-ILNREN--------------------------------------------------------------------------------SIVSSPCSSMYLLSPLKTLHITDKRPSYAEKVYGECNQEGPIPFSDCLS-TEQLEHCEKIGEGVFGEVFQIIN------DQTP-VALKIIAVEG-SDLVNGSHQKTFEEILPEIIISKELSLLSNEVYNCTEGFIGLNSVYCVQGLYPPLLLKAWDQYNTTKGSANDRPDFFQEDQLFIILEFEFGGIDLERMRTKLTSVATAKSILHQITASLAVAEASLHFEHRDLHWGNVLLKKTNLKELHYTLNGKTSTIPTHGLQVNIIDYTLSRLE-RDGIVVFCDISAEEDLFTGEG---------DYQFEIYRLMRKENKN--CWGEYHPYNNVLWLHYLTDKILNKMRFKTKCHSAAMK---------QIKRKLQHFHRTVLNFSSATDLLCRHSLFK-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z0R0-1", "uniprot_id": "HASP_MOUSE", "id": "Q9Z0R0-1", "name": "Serine/threonine-protein kinase haspin", "aln": "-MAQAHPRSGTRLFRTYAARGVRGSQRQPGGLAEQWFQP-------------PNLKRAFSSSLSD----SNESPAVASDDPDDPDFPGSLVGQRRRRPRGSGSRNQR---------------TLTNTPR---VQRLRPRPPQKCSTPCS-------------------RLRPPPFPNCSPGCLGSDHS-----------------VCIQSRDSNELGTSASLFSSPAS--PGAPDP------------LYADSAVPGSFH---------LPAASLSEPSVPCPQVAATG-DRYTGRALRAEASFRSSLFSLVNSGATEENKFGTDGENVKESCCERRQQMGNRLTDPDLTSPGKRKAA----CKKVVSQGVDQRDYEESSACKDLRVPGEISRPKRTGPLRKRKQQE-----------------------------------------------------------------------------ATGTPPRHYHQSKKKR---KASVSLWNLNTSQRDS--------------------------------------------WTKTRASFGFHKKKIIT----------------------------SVIEVCS--SVASSSSRSLLSECSTPPIKNRAH--------------------------------------------------------------------------------LTVSSRCSSVYLLSPLKTLHVTDQRPSYAEKVYGECNQEGPIPFSDCLS-TEKLERCEKIGEGVFGEVFQIIN------DQAP-VALKIIAIEG-LDLVNGSHQKTFEEILPEIIISKELSLLSSEAYNRTEGFIGLNSVHCVQGLYPPLLLKAWDHYNTTKRSANDRPDFFQEDQLFIILEFEFGGVDLERMKTKLSSVATAKSILHQITASLAVAEASLHFEHRDLHWGNVLLKKTNLKELRYTLNGKTSTIPTHGLQVNIIDYTLSRLE-RDGIVVFCDISAEEDLFTGEG---------DYQFEIYRLMRKENKN--CWGEYHPYNNVLWLHYLTDKILNKMKFKTKCQSAAMK---------QIRKNLQHFHRTVLSFSSATDLLCQHSLFR-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TF76-1", "uniprot_id": "HASP_HUMAN", "id": "Q8TF76-1", "name": "Serine/threonine-protein kinase haspin", "aln": "-MAASLPGPGSRLFRTYGAADGRR-QRRPGREAAQWFPP-------------QDRRRFFNSSGSSDASIGDPSQSDDPDDPDDPDFPGSPVRRRRRRPGGRVPKDRPSLTVTPKRWKLRARPSLTVTPR---RLGLRARPPQKCSTPCG-------------------PLRLPPFPSRDSGRLSPDLS-----------------VCGQPRDGDELGISASLFSSLASPCPGSPTPRDSVISIGTSACLVAASAVPSGLH---------LPEVSLDRASLPCSQEEATGGAKDTRMVHQTRASLRSVLFGLMNSGTPEDSEFRADGKNMRESCCKRKLVVGNGPEGPGLSSTGKRRATGQDSCQERGLQEAVRREHQEASVPKGRIVPRGIDRLERTRSSRKSKHQE-----------------------------------------------------------------------------ATETSLLHSHRFKKGQKLGKDSFPTQDLTPLQNVCF-------------------------------------------WTKTRASFSFHKKKIVT----------------------------DVSEVCSIYTTATSLSGSLLSECSNRPVMNRTSG-------------------------------------------------------------------------------APSSWHSSSMYLLSPLNTLSISNKKASDAEKVYGECSQKGPVPFSHCLP-TEKLQRCEKIGEGVFGEVFQTIA------DHTP-VAIKIIAIEG-PDLVNGSHQKTFEEILPEIIISKELSLLSGEVCNRTEGFIGLNSVHCVQGSYPPLLLKAWDHYNSTKGSANDRPDFFKDDQLFIVLEFEFGGIDLEQMRTKLSSLATAKSILHQLTASLAVAEASLRFEHRDLHWGNVLLKKTSLKKLHYTLNGKSSTIPSCGLQVSIIDYTLSRLE-RDGIVVFCDVSMDEDLFTGDG---------DYQFDIYRLMKKENNN--RWGEYHPYSNVLWLHYLTDKMLKQMTFKTKCNTPAMK---------QIKRKIQEFHRTMLNFSSATDLLCQHSLFK-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QA94-1", "uniprot_id": "A0A8M9QA94_DANRE", "id": "A0A8M9QA94-1", "name": "Serine/threonine-protein kinase haspin", "aln": "--MNARGKNGPVFIKTYSKRMRKLEPWISPDLRKAAFSFSSTFSSDQSIQETPKPKKRKIKETSSRTAKTKVMAAIKENKSDEENYSPSLPSRKKIHAKPSVKTTAMRKPRTTKRAKKSTQLNLSSSENDDDSIMINHVSSKTAANECAGNDKKVLNPPYLGKFVTSRRRPLPPIQTKQIAVLHHTLNSSDDFLPSSFQNKRRKTVCMKNYDSNKHAARKCLQNRVPLAEVSFNDSDDQHLPSKCPLLSSTPSVVCRQLKNLPEPSISEISSLSFDESGQPAENNNNSNGLDYVKECDIIPQANTKQQLQNPGVSSERVIELKEGEKDVTEKRKDDYREMVQHKRGFSVAMSAQTHTGFGCVSPQSQLQSLEEELKERCHKVETAVMLKKINISDHSSLLGCSKKQEERTALNSLESIMPAEILNSQTYVTVSSSCSTPSKASIYFSSSKSLSPSHLPEANQSLIERLKAECLLSSLAVCIPRLDLGMYSFIPHGVTKAPCTDKDSATSPTLKKAEHVMPDSPINHRTPGNLKAVVQHLFLPLQLPTVSPPASVANSKTRPPVVTKERAGTGTGRKVCVSGLNVSRWSKKGAGEFQDKRRKREGRTKAASGDYSSWGSMLSTGADTFVKESACGMVQGTSGMSLAVTPLRLEQMNLSSFLANFTPDNLTTHSWGRLKAALSLHKKKTAFPTPRRFAQSHLKSPGIGFPADNSLDLFASPFCTPSRMKSSQMLQSTMNTPMTTFQEDISDAEKVYQECQQSGPLSFSDCIP-PARMKHLNKIGEGTFGEVFSTIN------DSNESVALKIIPVEG-SQQVNGEHQKTFGEILHEIIISKELSSLNLKEFNKSDGFIGLNNLHCVRGCYPEALLKAWDKFDHQKGSENDRPDFFDDEQLFLILEFEFGGSDLENMNGKLSSMAQAKSVLHQVTASLAVAEQALCFEHRDLHWGNILVKNVKHKHNEFILNGTVHCIETRGVHVNIIDYSLSRLE-IDGLTVSCDISSDEELFMGQG---------DYQFEIYRLMKKENKN--CWSAYNPHSNVLWLHYLADKLLS-MNYRNKTQSSQQR---------TLKSALNAFKSEIMNYPSATEALMKCSFFQ-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P83103-1", "uniprot_id": "HASP_DROME", "id": "P83103-1", "name": "Serine/threonine-protein kinase haspin homolog", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLSISKTKMD-------------------------------------------------FLEEGRWKDPFDELLDSRTKLSKMNIVKQNVRVTYNIDSSVENSSYIEIKEPNHKNEPLTLEDCSIKVYCPSDSISTPCDKRLGG------------------------TTGLFETDLSPITRLKLEGVEDSRD------------------------------------------------------------------------------------KCADTNEADLYVNVEILFQNINSS-------------------------------------------------PKKCSNFGKKRLSNLN---------------------------KMVTAVHPSISLNPGKWRKSLNNFIRSKITETNFT-------------------------------------------------------------------------------KKVERRSSICQDRKSLVLKGEHKFENKYEEDVLKYCHQCTPLPFNTAYE-QHKLLNTKKIGEGAYGEVFRCSRNQEVLKDHISDIVLKIIPLEG-STVINGEKQKTFSQILPEIIITKKMCSLRTSKTNSTNGFVSIQKVSLVKGRYPPHFIKLWEKYDNEKGSENDHPELFGDNQLFAVLELKFAGSDMANFKFLNS--EQSYYALQQIILALAVGEEEYQFEHRDLHLGNILIEYTNKKHIVCTFKSSNLTLLSKGVNVTIIDYTLSRVT-INDCCYFNDLSRDEELFQATG---------DYQYDVYRMMRNELKN--NWSSFSPKTNIIWLSYVIVKVLDSVKYKSIN-TKVHR---------MYIDKIKELKNIIMTFESASHCANYLFNLN-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32789-1", "uniprot_id": "ALK2_YEAST", "id": "P32789-1", "name": "Serine/threonine-protein kinase Haspin homolog ALK2", "aln": "-MNFDAVADQQMTDRRYFALEVAESDDADSSLNSSSMGS--------------------PAVDVGRKVYKITSHKGSAEDESQSFFTSSDSPTSKTRPVG-------------------------------KTIENDDYYGKRSSTGSS------------------------------LKQLFNKIN-----------------INDTAHSSNKENVSQSVLS-----------------------------------------------ENKLLSPSKRLSKQGLTKVTNSKFRTPLRPISNQSTLSRDEPVKDFRSLKFRS-GSDFKCWGDEKTSSHVHSSSVNSVNSFTSTTSS------------------------SKWKFWKNDNLLSRSLSSRSVNDQD--------------------------------------------------------------------------------PNFVQPKPTNSLQKKSSISSFHNSIFGGGK----------------------------------------------HTEKKRNSGFIMPDHQS-----------------------------TKELNHKHSSSNLSFRSLKHKTSHSSLNKLKVR----------------------------------------------------------------------------------RKGNTQELNHPIKKTCQISLPVPDQVSKDKIQLKLKNSTSLASLSS-EVTPINTLDYNDSILQQILQLCDVKYILHDLREAQSLGLFTLNTRSVQLSHNFWQTYHSDMQTSLICKKVCLGALSDLTTSN-LISLHELKSLR-----LIQGTSGVANLLQAYVVPSNQCENDQNLILYLFFKYQGTPLS--RCSNIDYSQALSIFWQCSSILYVAESKFQLEHRNLTLDHILIDSK--------------------GNVTLIDMKCCRFLNIDNNKASYTRLDHHYFFQGRG---------TLQFEIYELMRSMLPQPISWATFEPRTNLLWLYHLSSSLLKMAKKAVVSGALNREENILIE-LTHLLDPARKHSKTIFKKELVIRTCGDLLSLKGEIMQ", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P43633-1", "uniprot_id": "ALK1_YEAST", "id": "P43633-1", "name": "Serine/threonine-protein kinase Haspin homolog ALK1", "aln": "MLLHFDIVIQLLSSHTLKSHQVEPPMDFETSFEEFVEDK---------------RFIALEVSDNDDDCDTDLTADTADELESSAILKMRESDASLNVTTGNNTSR-------------------KTTSNSKKRWSLLSNHSAVSSSKSK--------------------KRWSVLSSSFTSESHKDRE-----------------SRNVLQQKRKSLQSYSSLDTVAS-------------------------------------------NSSISASSSLKRSSTGLSLRQLFTKIGINDDISQPGIGIPQGKENLPPTMGKKNSSIASTSSENRLRTPLKPLVNHSKRPTSQPQQQQPLYNASLSSRRSSISSTVSSSSSSKWRFWKRNKNQTPALLQPDHHSLKTFP------------------------------------------------------------------------AVNRRDSMTPVEPRNMVKHKTSFSDFHKTIFSSNTYSE-------------------------------------------SSDTISSMEITLKNKAS-----------------------------SSSLSLNVLKKRNSQSSLKHKSSHASLQKFKRNK------------------------------------------------------------------GKSSMIAPSTATNSSNDDSCSYSSKNSTLSHRISLPVPDQVSRDKIQNKLRYSTSLLSLNSKSSLPMNKNDHDETLLRQILLNCDIK----RILNPAKGDVLPLIN-DVNHLSSIQLTSNVWQIGEVICKKVSLGTIDDITWDRKFLSLQELEKLK----IMQQKFDGIPQLLKSFVVKEANG----GLYLYLLFKDHGTPIS--LISLKNWKQILKIFWSCAGIIHGLEKNLKFEHRNLTLDNILIDGN--------------------GNITIIDFKCSRLQTPQDDVLYLRLDHPLFFLNGKDKSKINEYQYQFEFEIYQSMRILLNM--DASAFEPMTNLYWLYYLSRVLLKFGDRKLGKNDANRDKMARVINHLEMNLAVHKRGGQLFKRLETEDIKNTGDLLKLYK--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . . . . . . . . . : .. . . . : : . . . .: . . .: ::: ::.: . * :* *::. . . ::.::.: :: : : : * * :: * : : . : * :***:* .::*:. ::.:** . .*. :. :: . . ::::*. *: . : * .*: ** :: :*. . ::. . :. ", "identical_positions": 22, "similar_positions": 101, "identity": "1.96%" }, { "cls_id": "homologset.agr.MGI:1194499", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R1W2-1", "uniprot_id": "GSG1_MOUSE", "id": "Q8R1W2-1", "name": "Germ cell-specific gene 1 protein", "aln": "MAKMEFQKGSSDQRTFISAILNMLSLGLSTASLLSSEWFVGTQKVPKPLCGQSLAAKCFDMPMSLDGGIANTSAQEVVQYTWETGDDRFSFLAFRSGMWLSCEETMEEP-----------------------GEKCRRFIELTPPAQR---WLSLGAQTAYIGLQLISFLLLLTDLLLTTNPGCGLKLSAFAAVSLVLSGLLGMVAHMLYSQVFQATANLGPEDWRPHSWNYGWAFYTAWVSFTCCMASAVTTFNMYTRMVLEFKCRHSKSFNTNPSCLAQHHRCFLPPPLTCTTHAGEPLSSCHQYPSHPIRSVSEAIDLYS--ALQDKEFQQGISQELKEVVEPSVEE-QR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6AYL2-1", "uniprot_id": "GSG1_RAT", "id": "Q6AYL2-1", "name": "Germ cell-specific gene 1 protein", "aln": "---MEFQKGPSDQRTFVSAILNMLSLGLSTASLLSSEWFVGAQKVPKPLCGQSLAAKCFDMPMSLDGGITNASAQEVVQYTWEAGDDRFSFLTFRSGMWLSCEETVEEP-----------------------GEKCRRFIELTPPAQREVLWLSLGAQTAYIGLQFISFLLLLTDLLLTSNPGCGLKLSAFAAVSLVLSGLLGMVAHMLYLQVFQATANLGPEDWRPHSWNYGWAFYTAWVSFTCCMVSAVTTFNTYTRMVLEFKCRHGTSFNTNPSCRAQHHRCFLPP-LTCAVHAGEPSTSCHQHPSHPIRSVSESIDLYSAAALQDKKFQQENSQELKEATESSVEE-QC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q2KHT4-1", "uniprot_id": "GSG1_HUMAN", "id": "Q2KHT4-1", "name": "Germ cell-specific gene 1 protein", "aln": "MAKMELSKAFSGQRTLLSAILSMLSLSFSTTSLLSNYWFVGTQKVPKPLCEKGLAAKCFDMPVSLDG-DTNTSTQEVVQYNWETGDDRFSFRSFRSGMWLSCEETVEEPALLHPQSWKQFRALRSSGTAAAKGERCRSFIELTPPAKREILWLSLGTQITYIGLQFISFLLLLTDLLLTGNPACGLKLSAFAAVSSVLSGLLGMVAHMMYSQVFQATVNLGPEDWRPHVWNYGWAFYMAWLSFTCCMASAVTTFNTYTRMVLEFKCKHSKSFKENPNCLPHHHQCFPRR-LSSAAPTVGPLTSYHQYHNQPIHSVSEGVDFYS--ELRNKGFQRGASQELKEAVRSSVEEEQC", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **:.*. *.***::****.****.:**:****. ****:******** :.*********:**** :*:*:******.**:******* :************:*** **:** ********:* *****:* :*****:************* **.************ ************:* ******.********** ******** **:******.******* **********:*..**: **.* .:**:** *:.:. : * :* **: .:**:****.:*:** *::* **: ******....**** * ", "identical_positions": 230, "similar_positions": 60, "identity": "65.16%" }, { "cls_id": "homologset.agr.MGI:1194500", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0AC58GVF0-1", "uniprot_id": "A0AC58GVF0_DANRE", "id": "A0AC58GVF0-1", "name": "", "aln": "--------------------------MPNLPNLNSFGKLCGSGRSDDSLVLDRVKRKNSVRRMSIIEDGNVAEVLYLIPKQ-SMMEQLPFLNPTEYLILEKMAPPQMEPVAHPQDPHHPPGKLVIQCYKCGEPCKGEVLRVQSKHFHIKCFTCKVCGCDLAQGGFFMKNGEYLCTLDYQRLHGTRCNGCGDFVEGEVVTALGKTYHPTCFVCTVCKRPFPAGDRVTFNGKDCLCQRCVQPTSP-TSKDVSA-------------------------------------SSNCAGCGRDIKNGQALLALDSQWHLGCFKCKACGKVLSGEYISKDGSPYCEKDYQIHFGVQCEACHQFITGKVLEAGD-KHYHPSCARCSRCNQMFTEGEEMYLQGSTVWHPDCKNNSRVEEKYRAAWQRPKGKASPFDIFYPQSQIQSQGPGGSGPGRHPLGRHEPLPPSVTSLHQSERQPTRSSSESICSRPGSSIPGSPGHTIYAKVDNEIIDYKDLAAIPRVKAIYDIERPDMISYESLHSTSSTLERQGRHSPGEPVRASGGSPTRGRATTLPQDPSSLSAETSPRTLSPTPSAEGCYDMRERIIQRSTSQGSIGSPVYHRHNYIPPLSKSPQHFHRPGMLKL---------CSSLRSSNSDTRPTSPFRHHFLPHNKDSFCIGTEPSSGRSSPL----SSRPATPTLSLTPKHFHIPDQGINMYRKPPIYKQHDSAALAAQSKSADDIIKSSKFPAAHAP--RPEETAKIETDYWPCPPSLAALGSDG-RSRS--RDEEEEEQLKRRHLQEEHLSKIQSGLG--KLILKEEMEKEMNRERYVRSVAAQRFDSQYANCTTDSQTVKTSSLPGYGRNGLHRPQSTELSQYNSYG------DVCGGQRDFKPTQDAQDSITRMDRGMSMPNMLEYKVYPYEMLTVANRGRTKLPKDVDRTRLERHLAPDTFFDIFGMEIHEFDRLPLWKRNDMKKKAKLF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M6Z9H1-1", "uniprot_id": "A0A8M6Z9H1_DANRE", "id": "A0A8M6Z9H1-1", "name": "", "aln": "--------------------------MPSLPTLNSLGKLCGSGRSQ-HVNRTRIKRAHSVKRMSVIEDGRVAEVLYLIPKQ-SVKQQLPFINPDDYYMTESLTP-----VAHTQESHHQTEKPLIRCAKCGELCKGEVLRVQAKHFHIKCFTCKVCGCDLAQGGFFMKNGEYLCTLDYQRIHGTRCNICGEFVEGEVVTALGKTYHPTCFVCTICKRPFPAGDRVTFNGKDCLCQYCAEPMSPGPTKDVVG-------------------------------------PSSCAGCGRDIKNGQALLALERQWHLGCFKCKACAKVLTGEYISKDGAPFCERDYQLQFGVQCEACQQFITGKVLEAGD-KHYHPSCARCSRCNQMFTEGEEMYLQGSTVWHPSCKHSPRGEER--------------------------------------------------------QRPTRSSSESICSRPGSSIPSSPGHTIYAKVDNEILDYRDLAAIPKVKAIYDIERPDLINYEPLYTTS-LDESEERESVAELQ------SSRRESSPMPDD----------RTRSPTPSAEGYYDMRERILHRSTSQGSIGSPIYSRHNYTPTLSRSPQHFHRP--------------------------------------------------------------------------------DQGMNIYRKPPIYKQHDSAAFAAQSKSADDIIKSAKFPSAFAP--GPDYPTKIETDCWSFPNFHAALGTDG-RRRS--KEEDEEEIQKRRQIQEEHLNKIQSGLG--KMILKEEMEKEKIRERHARSLSAQR----YEHGSNQSSPSKTGSLPGYGRNGLHRPQSTDFTQYNSYG------DVCGGIREFQPMHDGHRTPTRMDRGVSMPNMLEPKVYPYEMLIITSRSRSKLPRDVDRTRLERHLAPEVFFEIFGMEIQEFNRLPLWKRNELKKKAKLF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8I5Y6A1-1", "uniprot_id": "A0A8I5Y6A1_RAT", "id": "A0A8I5Y6A1-1", "name": "", "aln": "MIGTATGKLCFLGFCVRSRCHVCHAEMPSFLGLRCLEKLCSSEKGK-GPSPERASLRGSHGRRLVIEDLSVPETPHPARHRHGTVTYLFYLYSSNRGPPELRFSSCDSSVAHPQDPHHSSEKPVIHCHKCGEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGDYLCTLDYQRMYGTRCHGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSS-SPKEATC-------------------------------------SSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSCGKVLTGEYISKDGSPYCEKDYQGLFGVKCEACHQFITGKVLEAGD-KHYHPSCARCSRCNQMFTEGEEMYLQGSTVWHPDCKQSTKTEEKLRP----PNIPRSSSDFFYPKSLIRRTG--------RSPALQHLSPPCLVNSNQNPRQPTRTSSESIYSRPGSSIPGSPGHTIYAKVDNEILDYKDLAAIPKVKAIYDIERPDLITYEPFYTSG-YEDKQDRQSLGESP----------------------------RTLSPTPSAEGFQDGRDRMIHRSTSQGSINSPVYSRHSYTPTTSRSPQHFHRPELLSPGVHRWSPLRTSSFSSTHSDTRPNPPFRHHFLPHVK-----GNEPSSGRNSPLPYRPDSRPLTPTYAQAPKHFHVPDQGINIYRKPPIYKQH--AALAAQNKASEDIIKFSKFPAAQAP--DPNEIPKIETDHWPGPPSLAAIGTDP-RRRSSGREEDEEELLRRRQLQEEQLMKLNSGLG--QLILKEEMEKE---NRERASLLASRYDS-PLHSASHAPSSKTSSLPGYGKSGLHRPVSTDFAQYNSYG------DVSGGVRDYQTLPDGHMPAMRMDRGVSMPNMLEPKIFPYEMLMVTNRGRNKILRDVDRTRLERHLAPEVFWEIFGMSIQEFDKLPLWRRNDMKKKAKLF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K4G5-1", "uniprot_id": "ABLM1_MOUSE", "id": "Q8K4G5-1", "name": "Actin-binding LIM protein 1", "aln": "--------------------------MPSLLGLKCLGKLCSSEIGK-VPSPERASLRNSH-RRLLIEDLSVPETPDPAHRRRGTVIHLVYLYSAGCGPPELRFSSYDPSVAHPQDPHHSSEKPVIHCHKCGEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGDYLCTLDYQRMYGTRCHGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSS-SPKEASC-------------------------------------SSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSCGKVLTGEYISKDGSPYCEKDYQGLFGVKCEACHQFITGKVLEAGD-KHYHPSCARCSRCNQMFTEGEEMYLQGSTVWHPDCKQSTKTEEKLRP----PNIPRSSSDFFYPKSLIRRTG--------RSPALQLLSPPCLTNSNKNPRQPTRTSSESIYSRPGSSIPGSPGHTIYAKVDNEILDYKDLAAIPKVKAIYDIERPDLITYEPFYTSG-YEDKQERQSLGESP----------------------------RTLSPTPSAEGYQDVRDRMIHRSTSQGSINSPVYSRHSYTPTTSRSPQHFHRPELLSPGVHRWSPLRTSSFSSTHSDSRPNPPFRHHFLPHVK-----GNEPSSGRNSPLPYRPDSRPLTPTYAQAPKHFHVPDQGINIYRKPPIYKQH--AALAAQSKASEDIIKFSKFPAAQAP--DPNEIPKIETDHWPGPPSLAAVGTDP-RRRSSGREEDEEELLRRRQLQEEQLMKLNSGLG--QLILKEEMEKE---SRERAS-LASRYDS-PLHSASHAPSSKTSSLPGYGKNGLHRPVSTDFAQYNSYG------DISGGVRDYQTLPDGHMPAVRMDRGVSMPNMLEPKIFPYEMLMVTNRGRNKILRDVDRTRLERHLAPEVFWEIFGMSIQEFDKLPLWRRNDMKKKAKLF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14639-1", "uniprot_id": "ABLM1_HUMAN", "id": "O14639-1", "name": "Actin-binding LIM protein 1", "aln": "--------------------------MPAFLGLKCLGKLCSSEKSK-VTSSERTSARGSNRKRLIVEDRRVSGTSFTAHRR-ATITHLLYLCPKDYCPRGRVCNSVDPFVAHPQDPHHPSEKPVIHCHKCGEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGTRCHGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSS-SPKETTF-------------------------------------SSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSCGKVLTGEYISKDGAPYCEKDYQGLFGVKCEACHQFITGKVLEAGD-KHYHPSCARCSRCNQMFTEGEEMYLQGSTVWHPDCKQSTKTEEKLR--------------------------------------------------------PTRTSSESIYSRPGSSIPGSPGHTIYAKVDNEILDYKDLAAIPKVKAIYDIERPDLITYEPFYTSG-YDDKQERQSLGESP----------------------------RTLSPTPSAEGYQDVRDRMIHRSTSQGSINSPVYSRHSYTPTTSRSPQHFHRP---------------------------------------------GNEPSSGRNSPLPYRPDSRPLTPTYAQAPKHFHVPDQGINIYRKPPIYKQH--AALAAQSKSSEDIIKFSKFPAAQAP--DPSETPKIETDHWPGPPSFAVVGPDM-KRRSSGREEDDEELLRRRQLQEEQLMKLNSGLG--QLILKEEMEKE---SRERSSLLASRYDS-PINSASHIPSSKTASLPGYGRNGLHRPVSTDFAQYNSYG------DVSGGVRDYQTLPDGHMPAMRMDRGVSMPNMLEPKIFPYEMLMVTNRGRNKILREVDRTRLERHLAPEVFREIFGMSIQEFDRLPLWRRNDMKKKAKLF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E1JIH3-1", "uniprot_id": "E1JIH3_DROME", "id": "E1JIH3-1", "name": "", "aln": "--------------------------------------------------------------MYILIYISIPKHPQTDKTR-------------------PIYPSTLGTELRTELGKTGQGKQKIYCAKCTKKCSGEVLRVADNHFHKACFQCCQCKKSLATGGFFTKDNAYYCIPDYQRLYGTKCANCQQYVEGEVVSTMGKTYHQKCFTCSKCKQPFKSGSKVTNTGKEVLCEQCVTGAPVSPSRQATGGGVSSPAPPAESPTRATAHQQHGSVISHKAHLKEDYDPNDCAGCGELLKEGQALVALDRQWHVSCFRCKACQAVLNGEYMGKDAVPYCEKCYQKGFGVKCAYCSRFISGKVLQAGDNHHFHPTCARCTKCGDPFGDGEEMYLQGSAIWHPRCGPGPSESGIILN----------------------------------GGGGTSSVVGGASNGNFTDTECDRMSSSALSEMYIRSRTPSFNGSLYSSSRKHYRTVSPGLILREYGRPNAEDISRIYTYSYLTDAPHYLRKPIDPYDKTPLSPHFHRPS--------------------SYATTASNAGSVAGSRPPSRPHSRTRSAMKVLVDAIRSETPRPKSPGMNNEEPIELSHYP----------AAKKPPPGEQPKIERDDFPAPPYPYTDPERRRRYSDTYKGVPASDDEDENVENGKPNGKVKNGEEQQRLQREAEQLEKLNSGIGSAIAKDLKEHAKYRKWKQNNLDPRNASRTPSASKEPLYKLRYESPIGASPSRNLDHQKPFYEDEMFDRSTSYRGSLGKSLGNAPSYNAIHSYRSPPKPGYGFKTTTLPYIRNGFSSDFSYGGLGDKTHSTDLSCGKSEASVDSITEGDRRALMGGDLPASSTYSGALSYHYPQAGLIRRSLPNMSHSMLVHEPAKIYPYHLLLITN---YRLPSDVDRCNLERHLSDIEFEHILQCARSEFYRLPQWRRNELKRRVKLF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: :. : :.: : * * * ** : *.****** :*** ** * * .** **** *:. * * ****::**:* * ::******:::***** .**.*: **:** .*.:** .*:: **: *. . ..::. ...*****. :*:****:**: ***:.**:**:* **.***:.**. *:**: ** ***:* * :**:****:*** :*:**:****::*.: * :*********::*** * .. . * **.:: . * . * . ::*:. :. : . : . : .*. : : :.:..* . . * :* ::.:: : :. * . . : ..* :: .: *:. :: . :* * .: * *: .. .. ..: : :*.. : . : ::* * . * * .. : * . . : : * . .: . *:. *: : * . .* .:: . : . ** *::**.:* ::. :: :*** .*****: * .*: ** :** *:**::*::.***", "identical_positions": 184, "similar_positions": 192, "identity": "18.55%" }, { "cls_id": "homologset.agr.MGI:1194503", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P18596-2", "uniprot_id": "AT2A3_RAT", "id": "P18596-2", "name": "Sarcoplasmic/endoplasmic reticulum calcium ATPase 3", "aln": "MEEAHLLSAADVLRRFSVTAEGGLTLEQVTDARERYGPNELPTEEGKSLWELVVEQFEDLLVRILLLAALVSFVLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALKEYEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGESVSVTKHTDAIPDPRAVNQDKKNMLFSGTNIASGKALGVAVATGLHTELGKIRSQMAAVEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFVVAEAEAGACRLHEFTISGTTYTPEGEVRQGEQLVRCGQFDGLVELATICALCNDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLKGLSRVERAGACNSVIKQLMQKEFTLEFSRDRKSMSVYCTPTRADPKAQGSKMFVKGAPESVIERCSSVRVGSRTVPLSATSREHILAKIRDWGSGSHTLRCLALATRDTPPRKEDMQLDDCSQFVQYETGLTFVGCVGMLDPPRPEVAACITRCSRAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVLGKAYTGREFDDLSPEQQRQACRTARCFARVEPAHKSRIVENLQSFNEITAMTGDGVNDAPALKKAEIGIAMGSGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLPRNPREALISGWLFFRYLAIGVYVGLATVAAATWWFLYDAEGPQVTFHQLRNFLKCSEDNPLFAGIDCEVFESRFPTTMALSVLVTIEMCNALNSVSENQSLLRMPPWLNPWLLGAVVMSMALHFLILLVPPLPLIFQVTPLSGRQWGVVLQMSLPVILLDEALKYLSRHHVDEKKDLK---------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q64518-2", "uniprot_id": "AT2A3_MOUSE", "id": "Q64518-2", "name": "Sarcoplasmic/endoplasmic reticulum calcium ATPase 3", "aln": "MEEAHLLSAADVLRRFSVTAEGGLSLEQVTDARERYGPNELPTEEGKSLWELVVEQFEDLLVRILLLAALVSFVLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALKEYEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGESVSVTKHTDAIPDPRAVNQDKKNMLFSGTNIASGKALGVAVATGLQTELGKIRSQMAAVEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFVVAEAEAGTCRLHEFTISGTTYTPEGEVRQGEQPVRCGQFDGLVELATICALCNDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLKGLSRVERAGACNSVIKQLMRKEFTLEFSRDRKSMSVYCTPTRADPKVQGSKMFVKGAPESVIERCSSVRVGSRTAPLSTTSREHILAKIRDWGSGSDTLRCLALATRDTPPRKEDMHLDDCSRFVQYETDLTFVGCVGMLDPPRPEVAACITRCSRAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVLGKAYTGREFDDLSPEQQRQACRTARCFARVEPAHKSRIVENLQSFNEITAMTGDGVNDAPALKKAEIGIAMGSGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKPPRNPREALISGWLFFRYLAIGVYVGLATVAAATWWFLYDTEGPQVTFYQLRNFLKCSEDNPLFAGIDCKVFESRFPTTMALSVLVTIEMCNALNSVSENQSLLRMPPWLNPWLLGAVVMSMALHFLILLVPPLPLIFQVTPLSGRQWGVVLQMSLPVILLDEALKYLSRNHMDEKKDLK---------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q93084-2", "uniprot_id": "AT2A3_HUMAN", "id": "Q93084-2", "name": "Sarcoplasmic/endoplasmic reticulum calcium ATPase 3", "aln": "MEAAHLLPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRILLLAALVSFVLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALKEYEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMAAVEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALCNDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMRKEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPLTPTSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVGCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVAGKAYTGREFDDLSPEQQRQACRTARCFARVEPAHKSRIVENLQSFNEITAMTGDGVNDAPALKKAEIGIAMGSGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLPRSPREALISGWLFFRYLAIGVYVGLATVAAATWWFVYDAEGPHINFYQLRNFLKCSEDNPLFAGIDCEVFESRFPTTMALSVLVTIEMCNALNSVSENQSLLRMPPWMNPWLLVAVAMSMALHFLILLVPPLPLIFQVTPLSGRQWVVVLQISLPVILLDEALKYLSRNHMHEEMSQK---------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A2R8QJH4-1", "uniprot_id": "A0A2R8QJH4_DANRE", "id": "A0A2R8QJH4-1", "name": "Calcium-transporting ATPase", "aln": "MENAHTKSASEVLANFGVNENTGLTLEQVKNNFDKYGPNELPAEEGKSLWELVVEQFEDLLVRILLLAACVSFVLALFEEGEESTTAFVEPIVILLILVANAVIGVWQERNAENAIEALKEYEPEMGKVYRMNRTAVQRIKARDIVPGDIVEISVGDKVPADIRITSIKSTTLRVDQSILTGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGRAIGVVVSTGVSTEIGKIRNQMAATEQEKTPLQQKLDEFGQQLSKVISLICIAVWVINIGHFADPVHGGSWIRGAIYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFVVNKADDSSCSLHEFTISGSTYAPEGEVLKADKQVQCGDYDGLVELATICSLCNDSSLDYNEAKGVYEKVGEATETALTTLVEKMNVFKTDLSGLSKVDRAAACNLIIRQLMQKKFTLEFSRDRKSMSVYCTPNGTNSQ---SKMFVKGAPEGVIDRCQFVRVGKERFPLTMAVKEELMSTIRDWGTGRDTLRCLALATRDSPPAVDKMDLENAGKFAEYESSLTFVGCVGMLDPPRKEVIGSIKLCNKAGIRVIMITGDNKGTAVAICRRIGIFSENEDVEGRAYTGREFDDLAPEAQREAVKRARCFARVEPAHKSKIVAYLQSFDEITAMTGDGVNDAPALKKAEIGIAMGSGTAVAKSASEMVLSDDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMDKPPRNPKEPLISGWLFFRYLAIGGYVGLGTVSAATWWYLFDEDGPQVSFYQLRHFMQCTEENPMFEGINCEVFESRYPTTMALSVLVTIEMFNALNSLSENQSLLRMPPWVNIWLLGAIILSLSLHFLILHVEPLPLIFQVTPLHFSQWIIVFKISIPVILLDEALKYISRHHLEGEEEDRYRKNRQLKF------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P22700-1", "uniprot_id": "ATC1_DROME", "id": "P22700-1", "name": "Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type", "aln": "MEDGHSKTVEQSLNFFGTDPERGLTLDQIKANQKKYGPNELPTEEGKSIWQLVLEQFDDLLVKILLLAAIISFVLALFEEHEETFTAFVEPLVILLILIANAVVGVWQERNAESAIEALKEYEPEMGKVVRQDKSGIQKVRAKEIVPGDLVEVSVGDKIPADIRITHIYSTTLRIDQSILTGESVSVIKHTDAIPDPRAVNQDKKNILFSGTNVAAGKARGVVIGTGLSTAIGKIRTEMSETEEIKTPLQQKLDEFGEQLSKVISVICVAVWAINIGHFNDPAHGGSWIKGAIYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVSRMFIFDKVEGNDSSFLEFEMTGSTYEPIGEVFLNGQRIKAADYDTLQELSTICIMCNDSAIDYNEFKQAFEKVGEATETALIVLAEKLNSFSVNKSGLDRRSAAIACRGEIETKWKKEFTLEFSRDRKSMSSYCTPLKASRLGTGPKLFVKGAPEGVLERCTHARVGTTKVPLTSALKAKILALTGQYGTGRDTLRCLALAVADSPMKPDEMDLGDSTKFYQYEVNLTFVGVVGMLDPPRKEVFDSIVRCRAAGIRVIVITGDNKATAEAICRRIGVFAEDEDTTGKSYSGREFDDLSPTEQKAAVARSRLFSRVEPQHKSKIVEFLQSMNEISAMTGDGVNDAPALKKAEIGIAMGSGTAVAKSAAEMVLADDNFSSIVSAVEEGRAIYNNMKQFIRYLISSNIGEVVSIFLTAALGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKPPRKADEGLISGWLFFRYMAIGFYVGAATVGAAAWWFVFSDEGPKLSYWQLTHHLSCLGGGDEFKGVDCKIFSDPHAMTMALSVLVTIEMLNAMNSLSENQSLITMPPWCNLWLIGSMALSFTLHFVILYVDVLSTVFQVTPLSAEEWITVMKFSIPVVLLDETLKFVARKIADGESPIYKMHGIVLMWAVFFGLLYAMML", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** .* .. : * *.. : **: *:. .:*******:*****:*:**:***:****:****** :***** *** **: ******:**:***:***::*********.*************** * ::..:*:::*::*****:**::****:***:*: * *****:************ ***:.:************:******:::*:* **.:.**: * :****.:*: .* :****:******.***:.**:**:***.****** **.*****::**:**********************************:***********************************.***:. :.: . . : ** ::*:** * *** : ::..::* * **:*** :****::**** * .:*********** *.**:* *..: ..*.: . * **. *. :*:************* **** . .*:*******.*::** .***. **: : : .::: ::*:* .********. *:* :.*.* :. :* :** .***** ******** ** .* * *****::******.** *****:*:*.: **. *::*:*******:* *: * :* *:**** ***:** ***::**:********************************:****:****::**:*********.*************:****.***** *************************************:* **.. * **********:*** *** .**.**:**:::. :**::.: ** :.:.* . * *::*::*.. .. ************ **:**:******: **** * **: :: :*::***:** * *. :****** :* *:::*:**:****:**:::*: . : ", "identical_positions": 625, "similar_positions": 223, "identity": "61.27%" }, { "cls_id": "homologset.agr.MGI:1194504", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P78508-1", "uniprot_id": "KCJ10_HUMAN", "id": "P78508-1", "name": "ATP-sensitive inward rectifier potassium channel 10", "aln": "MTSVA----------KVYYSQTTQTE------SRPLMGPG-----------------IRRRR-------------------------------------------------------VLTKDGRSNVRMEHIADKRFLYLKDLWTTFIDMQWRYKLLLFSATFAGTWFLFGVVWYLVAVAHGDLLELDPPANHT-----PCVVQVHTLTGAFLFSLESQTTIGYGFRYISEECPLAIVLLIAQLVLTTILEIFITGTFLAKIARPKKRAETIRFSQHAVVASHNGKPCLMIRVANMRKSLLIGCQVTGKLLQTHQTKEGENIRLNQVNVTFQVDTASDSPFLILPLTFYHVVDETSPLKDLPLRSG------EGDFELVLILSGTVESTSATCQVRTSYLPEEILWGYEFTPAISLSASG-KYIADFSLFDQVVKVASP-------------SGLRDSTVRYGDPEKLKLEESLREQAEKEG----SALSVRISNV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9JM63-1", "uniprot_id": "KCJ10_MOUSE", "id": "Q9JM63-1", "name": "ATP-sensitive inward rectifier potassium channel 10", "aln": "MTSVA----------KVYYSQTTQTE------SRPLVAPG-----------------IRRRR-------------------------------------------------------VLTKDGRSNVRMEHIADKRFLYLKDLWTTFIDMQWRYKLLLFSATFAGTWFLFGVVWYLVAVAHGDLLELGPPANHT-----PCVVQVHTLTGAFLFSLESQTTIGYGFRYISEECPLAIVLLIAQLVLTTILEIFITGTFLAKIARPKKRAETIRFSQHAVVASHNGKPCLMIRVANMRKSLLIGCQVTGKLLQTHQTKEGENIRLNQVNVTFQVDTASDSPFLILPLTFYHVVDETSPLKDLPLRSG------EGDFELVLILSGTVESTSATCQVRTSYLPEEILWGYEFTPAISLSASG-KYIADFSLFDQVVKVASP-------------SGLRDSTVRYGDPEKLKLEESLREQAEKEG----SALSVRISNV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49655-1", "uniprot_id": "KCJ10_RAT", "id": "P49655-1", "name": "ATP-sensitive inward rectifier potassium channel 10", "aln": "MTSVA----------KVYYSQTTQTE------SRPLVAPG-----------------IRRRR-------------------------------------------------------VLTKDGRSNVRMEHIADKRFLYLKDLWTTFIDMQWRYKLLLFSATFAGTWFLFGVVWYLVAVAHGDLLELGPPANHT-----PCVVQVHTLTGAFLFSLESQTTIGYGFRYISEECPLAIVLLIAQLVLTTILEIFITGTFLAKIARPKKRAETIRFSQHAVVAYHNGKLCLMIRVANMRKSLLIGCQVTGKLLQTHQTKEGENIRLNQVNVTFQVDTASDSPFLILPLTFYHVVDETSPLKDLPLRSG------EGDFELVLILSGTVESTSATCQVRTSYLPEEILWGYEFTPAISLSASG-KYVADFSLFDQVVKVASP-------------GGLRDSTVRYGDPEKLKLEESLREQAEKEG----SALSVRISNV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E7FD27-1", "uniprot_id": "E7FD27_DANRE", "id": "E7FD27-1", "name": "", "aln": "MTSATPPSSRSSSPQKVCHSQTQTDV------LKPLLGGGGGGTS----TGNGPAALRRRRR-------------------------------------------------------VLSKDGRSNVRIEHVSGRGTLYLRDLWTTFLDMQWRYKLFLFSATFAGTWFVFGVLWYLVALVHGDLLEFDPPSNHT-----PCVMQVQTLTGAFLFSLESQTTIGYGFRCITEECPLAIILLIVQLVITMVMEIFITGTFLAKVARPKKRGETVKFSQHAVVANHEGRPCLMIRVANMRKSLLLGCQVSGKLLQTSQTKEGETVRLDQRNVAFQVDTSSDSPFLILPLTFYHVIDDNSPLRAWAAKGGGWTDPELADFELLVIMSATVEPTSATCQVRTSYLPDEILWGYEFPPVVSLSPSG-KYVADFAFFDKVAKTKTPPLFKQAPPSHTQTPQHQGSGEKGADTEKMRLEESYREERGRDRGRVRDQLSVRISNV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "B7YZX2-1", "uniprot_id": "B7YZX2_DROME", "id": "B7YZX2-1", "name": "", "aln": "MQSDASPLGAAATDSLTMHRSTSMPVKPKPLEQKPLLRSSEKETVNASDYYPESPGFVRRRRSKAAGDHLETRSEQNPTFSFPYAHDWAGSTIELTPDLGSGPRTSSSDGLRRSLNRVMEKNGKENVVFRRIPEKSWRYMRDLVTTLMELEWKYMLTLFLGSYFLSWLLFAALCYVVAYSHGDFIFDPVSGKRMGEGVDPCIYGVHSWVAMIIYSVETQTTLGFGEKYASEECPETIFLFVMQMLSAALIEGCMVSVIYAKTARPARQLTKLKFSDKAVICYRDGRLCLLFRVCDPREQQSIESKIRVYIIVDKRTREGETIKS---HVELKLEGNGEQ-IILWPDVVCHVIDETSPLSQFTTAKLFN----AAQFELYVSIVGTSPATAQMTEAKTSYLPREIFWGQRFVNIIHYDAQNERYIVDYENFNRTISVDMP----------------------MTNPKNDHLKLEYRK--------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * : . : .* :**: . **** *: *:*:.** :.::. : *::** **:::::*:* * ** .:: :*::*..: *:** ***:: ..:: **: *:: .. :::*:*:***:*:* : :**** :*.*:: *:: : ::* :...: ** *** :: .::**::**:. ::*: **::**.: *:. : .:: :: :*:***.:: :* :::: .:. ::: * .. **:*:.*** . .:*** : : .* .*: :.:***** **:** .* : .... :*:.*: *::. .. * :.:: :*: . *: ", "identical_positions": 98, "similar_positions": 149, "identity": "19.76%" }, { "cls_id": "homologset.agr.MGI:1194505", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35796-1", "uniprot_id": "C1QBP_RAT", "id": "O35796-1", "name": "Complement component 1 Q subcomponent-binding protein, mitochondrial", "aln": "MLPLLRCVPRALGAAAT-GLRASIPAPPLRHLLQPAPRPCLRPFGLLSVRAGSARRSGLLQP--PVPCA-CGCGALHTEGDKAFVEFLTDEIKEEKKIQKHKSLPKMSGDWELEVNG-TEAKLLRKVA-GEKITVTFNINNSIPPTFDGEEEPSQGQKAE---EQEPELTST--PNFVVEVTKTD-GKKTLVLDCHYPEDEIGHED-EAESDIFSIKEVSFQTTGDSEWRDTNYTLNTDSLDWALYDHLMDFLADRGVDNTFADELVELSTALEHQEYITFLEDLKSFVKSQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35658-1", "uniprot_id": "C1QBP_MOUSE", "id": "O35658-1", "name": "Complement component 1 Q subcomponent-binding protein, mitochondrial", "aln": "MLPLLRCVPRSLGAAS--GLRTAIPAQPLRHLLQPAPRPCLRPFGLLSVRAGSARRSGLLQP--PVPCA-CGCGALHTEGDKAFVEFLTDEIKEEKKIQKHKSLPKMSGDWELEVNG-TEAKLLRKVA-GEKITVTFNINNSIPPTFDGEEEPSQGQKAE---EQEPERTST--PNFVVEVTKTD-GKKTLVLDCHYPEDEIGHED-EAESDIFSIKEVSFQATGDSEWRDTNYTLNTDSLDWALYDHLMDFLADRGVDNTFADELVELSTALEHQEYITFLEDLKSFVKNQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q07021-1", "uniprot_id": "C1QBP_HUMAN", "id": "Q07021-1", "name": "Complement component 1 Q subcomponent-binding protein, mitochondrial", "aln": "MLPLLRCVPRVLGSSVA-GLRAAAPASPFRQLLQPAPRLCTRPFGLLSVRAGSERRPGLLRPRGPCACG-CGCGSLHTDGDKAFVDFLSDEIKEERKIQKHKTLPKMSGGWELELNG-TEAKLVRKVA-GEKITVTFNINNSIPPTFDGEEEPSQGQKVE---EQEPELTST--PNFVVEVIKNDDGKKALVLDCHYPEDEVGQED-EAESDIFSIREVSFQSTGESEWKDTNYTLNTDSLDWALYDHLMDFLADRGVDNTFADELVELSTALEHQEYITFLEDLKSFVKSQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1R3F7-1", "uniprot_id": "F1R3F7_DANRE", "id": "F1R3F7-1", "name": "Complement component 1 Q subcomponent-binding protein, mitochondrial", "aln": "---MLKSVTRAL------QLSARLSSRSSANRTAPISR---SFWSLRSPGAAAASRPKILTAARALPTLSCGCGGLHTDGDKAFAEFLTEEIKEEKKIQKSKSLPKMSGGWELELNG-TEAKLIRSLS-GEKVTITFNVNNSIPPQLE--EEPEQTQKSQ---EEEPDIVST--PNFVVEVTKSG-AKNSLVFDCHFPEDEVGHGDGEEESDIFTIREVSFQPEGEEDWKETSYTLNTDSLDWALYDHLMDFLADRGVDNTFADELMELSTALEHQEYIKFLEDLGTFVKCK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P40513-1", "uniprot_id": "MAM33_YEAST", "id": "P40513-1", "name": "Mitochondrial acidic protein MAM33", "aln": "--MFLRSVNRAVTRSILTTPKPAVVKSSWRVFTVANSKRCFTPAAIMR-NQETQRVGDILQS---------------------ELKIEKETLPESTSLDSFNDFLNKYKFSLVETPGKNEAEIVRRTESGETVHVFFDVAQIANLPYNNAMDENTEQNEDGINEDDFDALSDNFANVNVVISKESASEPAVSFELLMNLQEGSFYVDSATPYPSVDAALNQSAEAEITRELVYHGPPFSNLDEELQESLEAYLESRGVNEELASFISAYSEFKENNEYISWLEKMKKFFH--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*:.* * : . . . .: .: : :* . .: .: : *. .::. : : : :* * .**:::* **.: : *:: : : : . *: : *:: : * .*. * : * . .: :: :: :* . . . :. .. .: . . : ..** * : * :* .***:: :*. : * *::***.:**.: .*.: ", "identical_positions": 37, "similar_positions": 88, "identity": "12.67%" }, { "cls_id": "homologset.agr.MGI:1194506", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JLD2-1", "uniprot_id": "NEUS_RAT", "id": "Q9JLD2-1", "name": "Neuroserpin", "aln": "MAYLGLLSLVALQSLVTGAAFPDETIAEWSVNVYNHLRATGEDENILFSPLSIALAMGVMELGAQGSTLKEIRHSMGYESLKSGEEFSFLRDFSSMVSAEEGQYVMKIANSLFVQNGFHINEEFLQMMKMYFNAEVNHVDFSENVAVANYINKWVENYTNSLLKDLVSPGDFDAVTHLALINAVYFKGNWKSQFRPENTRTFSFTKDDESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDEISMMLVLSRQEVPLATLEPLLKPQLIEEWANSVKKQKVEVYLPRFTVEQEIDLKDILKALGVTEIFIKDANLTAMSDKKE-LFLSKAVHKSFIEVNEEGSEAAVASGMIAISRMAVLFP----QVIVDHPFLFLIKNRKTGTILFMGRVMHPETMNTSGHDFEEL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35684-1", "uniprot_id": "NEUS_MOUSE", "id": "O35684-1", "name": "Neuroserpin", "aln": "MTYLELLALLALQSVVTGATFPDETITEWSVNMYNHLRGTGEDENILFSPLSIALAMGMMELGAQGSTRKEIRHSMGYEGLKGGEEFSFLRDFSNMASAEENQYVMKLANSLFVQNGFHVNEEFLQMLKMYFNAEVNHVDFSQNVAVANSINKWVENYTNSLLKDLVSPEDFDGVTNLALINAVYFKGNWKSQFRPENTRTFSFTKDDESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDEISMMLALSRQEVPLATLEPLLKAQLIEEWANSVKKQKVEVYLPRFTVEQEIDLKDILKALGVTEIFIKDANLTAMSDKKE-LFLSKAVHKSCIEVNEEGSEAAAASGMIAISRMAVLYP----QVIVDHPFLYLIRNRKSGIILFMGRVMNPETMNTSGHDFEEL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99574-1", "uniprot_id": "NEUS_HUMAN", "id": "Q99574-1", "name": "Neuroserpin", "aln": "MAFLGLFSLLVLQSMATGATFPEEAIADLSVNMYNRLRATGEDENILFSPLSIALAMGMMELGAQGSTQKEIRHSMGYDSLKNGEEFSFLKEFSNMVTAKESQYVMKIANSLFVQNGFHVNEEFLQMMKKYFNAAVNHVDFSQNVAVANYINKWVENNTNNLVKDLVSPRDFDAATYLALINAVYFKGNWKSQFRPENTRTFSFTKDDESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDEISMMLVLSRQEVPLATLEPLVKAQLVEEWANSVKKQKVEVYLPRFTVEQEIDLKDVLKALGITEIFIKDANLTGLSDNKE-IFLSKAIHKSFLEVNEEGSEAAAVSGMIAISRMAVLYP----QVIVDHPFFFLIRNRRTGTILFMGRVMHPETMNTSGHDFEEL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1Z6R3-1", "uniprot_id": "A1Z6R3_DROME", "id": "A1Z6R3-1", "name": "", "aln": "---------------MKDEEFAQG-LEQFALCLHDHLCRASAGLNIIYSPLSIHISAAMLRMGTSEGSATAKEMDEGLR-FGGLEAQQVAESFGVVLKSYEQCQVLKMANGLYVMKGLQVDEQFGHILEQKFRSKPMEIDFGSEQAAS-IINKWVESQTNNLIKDIIGPRVLTKDSRLCLVNGIHFKGEWSISFNEKETREEDFFGSDRP-TRVRMMHVCENFFFAVLPMFEATA------LRMNYSACNLAMIILLPDEKSNLTSLEKKLSDISLEVVSSAMNLEKVDVKIPSFTAEFQQELSQVLMLMGMNRIFSGQAELGGMLQSEESLFVSQIVHKAFIEINEVGTEAAAATAAVATFRSMPARQGPPKVFHANRPFFYAIKDNTHG-LLFAGHFITTKVEQSEKCNTCT-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. *.: : : :: ::::* :. . **::***** :: .::.:*:. .: . . . * : . * .. ..*. : .: * *:*:**.*:* :*::::*:* :::: *.: .:**..: *.: ******. **.*:**::.* : : *.*:*.::***:*. .*. ::** .* .*.. .:: **: :*::. :. . * *.: *.. :::*:: *. :: *::** :. :* :.::: :**:* :* **.* : :*.::* :*:..** :*:* .: :.:* :*:*: :**: :*:** *:***..:. :* * . .::**:: *::. * :** *:.: .:. ::. : ", "identical_positions": 98, "similar_positions": 173, "identity": "23.61%" }, { "cls_id": "homologset.agr.MGI:1194508", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q641Y0-1", "uniprot_id": "OST48_RAT", "id": "Q641Y0-1", "name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit", "aln": "---------------MKMVPRLAVRAWPLCGLLLAALGCVCASGPRTLVLLDN-LNVRDTHSLFFRSLKDRGFELTFKTADDPSLSLIKYG--EFLYDNLIIFSP-SVEDFGGNINVETISAFIDGGGSVLVAASS-DIGDPLRELGSECGIEFDEEKTAVIDHHNYDVSDLGQHTLIVADTENLLKAPTIVGKSS----LNPILFRGVGMVADPDNPLVLDILTGSSTSYSFFPDKPITQYPHAVGRNTLLIAGLQARNNARVIFSGSLDFFSDAFFNSAVQKAAPGAQRYSQTGNYELAVALSRWVFKEEGVLRVGPVSHHRVGETAPPN-AYTVTDLVEYSIVIEQLSNGKWVPFDGDDIQLEFVRIDPFVRTFLKRK------GGKYSVQFKLPDVYGVFQFKVDYNRLGYTHLYSSTQVSVRPLQHTQYER--FIPSAYPYYASAFSMMAGLFLFSVVFLHMK---------EKEKSD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O54734-1", "uniprot_id": "OST48_MOUSE", "id": "O54734-1", "name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit", "aln": "---------------MKMDPRLAVRAWPLCGLLLAVLGCVCASGPRTLVLLDN-LNVRDTHSLFFRSLKDRGFELTFKTADDPSLSLIKYG--EFLYDNLIIFSP-SVEDFGGNINVETISAFIDGGGSVLVAASS-DIGDPLRELGSECGIEFDEEKTAVIDHHNYDVSDLGQHTLIVADTENLLKAPTIVGKSS----LNPILFRGVGMVADPDNPLVLDILTGSSTSYSFFPDKPITQYPHAVGRNTLLIAGLQARNNARVIFSGSLDFFSDAFFNSAVQKATPGAQRYSQTGNYELAVALSRWVFKEEGVLRVGPVSHHRVGEMAPPN-AYTVTDLVEYSIIIEQLSNGKWVPFDGDDIQLEFVRIDPFVRTFLKRK------GGKYSVQFKLPDVYGVFQFKVDYNRLGYTHLYSSTQVSVRPLQHTQYER--FIPSAYPYYASAFSMMAGLFIFSIVFLHMK---------EKEKSD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P39656-1", "uniprot_id": "OST48_HUMAN", "id": "P39656-1", "name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit", "aln": "MGYFRCARAGSFGRRRKMEPSTAARAWALFWLLLPLLGAVCASGPRTLVLLDN-LNVRETHSLFFRSLKDRGFELTFKTADDPSLSLIKYG--EFLYDNLIIFSP-SVEDFGGNINVETISAFIDGGGSVLVAASS-DIGDPLRELGSECGIEFDEEKTAVIDHHNYDISDLGQHTLIVADTENLLKAPTIVGKSS----LNPILFRGVGMVADPDNPLVLDILTGSSTSYSFFPDKPITQYPHAVGKNTLLIAGLQARNNARVIFSGSLDFFSDSFFNSAVQKAAPGSQRYSQTGNYELAVALSRWVFKEEGVLRVGPVSHHRVGETAPPN-AYTVTDLVEYSIVIQQLSNGKWVPFDGDDIQLEFVRIDPFVRTFLKKK------GGKYSVQFKLPDVYGVFQFKVDYNRLGYTHLYSSTQVSVRPLQHTQYER--FIPSAYPYYASAFSMMLGLFIFSIVFLHMK---------EKEKSD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NYS8-1", "uniprot_id": "OST48_DANRE", "id": "Q6NYS8-1", "name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit", "aln": "---------------MATALSGGFSKNALFILSAALMLQAVLGDGKTLVLLDN-PNIRDTHSIFFRSLADRGFDLTFKTADDPGLSLIKYG--QFLYDHLILFSP-SVEDFGGNINVETITAFIDGGGNVLVAASS-DIGDPLRELGSECGIEFDEEKTAVIDHHNYDISDPGEHTLIVADPENLLKAPTIVGKPT----DKPVLFKGVGMVADPDNPLVLDILTGSSTSYSYFPDRPITQYPHAVGKNTLLIAGLQARNNARVVFSGSLHFFSDAFFNSAVQKAATGSKRYEQTGNQDLAEALSRWVFKEAGVLRVGDVTHHPVGESTPPA-AYTVTDLVEYGIVIEMLSGGKWVPFDGDDIQLEFVRIDPFVRTYLKKN------GGKYSVQFKLPDVYGVFQFKVDYNRLGYTHLYSSTQVSVRPLQHTQYER--FIPSAFPYYASAFSMMAGLFVFSVVFLHMR---------EKEKSD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24319-1", "uniprot_id": "OST48_DROME", "id": "Q24319-1", "name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit", "aln": "---------------------MMWKALLIAVLAIAHCQAVLETDANTLVLLDN-LAIRETHSIFFKSLQDRGFKLTYKLADDSSLLLSKYG--EYLYKNVIIFAP-SVEEFGGDVSVERLAQFVDDGGNVLVAGSE-KSGDALREFASECGFELDEENAAVIDHLHYDVSDAGEHTTILTSAKNLIQADTIVGKANRQADAAPLLYRGTGLIADKENPLVLKLLTAESTAYSYNPEASVSDYPHAVGRGTLLIAALQARNNARVVFSGSLLFFSDESFTTAVQYAQSG-VFHKLAGNRDVAESISKWVFGETGRLRVASVQHHKEGELLPPDQAYTITDPVVYTIGIEELVQGEWRAFKASDIQLEFVRIDPFVRTYLKQTN-----TGAYQAKFKIPDVYGVYQFKVDYNRVGYTHLYSTTQVSVRPLEHTQYER--FIPSAFPYYTSAFSMMIGVFVFSFVFLHFKDEPVGRAAKEDKKSQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P33767-1", "uniprot_id": "OSTB_YEAST", "id": "P33767-1", "name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit WBP1", "aln": "---------------------MRTDWNFFFCILLQAIFVVGTQTSRTLVLYDQSTEPLEEYSVYLKDLEQRNYKLEYLDINSTSTTVDLYDKEQRLFDNIIVFPTKGGKNLARQIPVKQLIKFFENEGNILCMSSPGAVPNTIRLFLNELGIYPSPKGHVIRDYFSPSSEE------LVVSSNHLLNKYVYNARKS-----EDFVFGESSAALLENREQIVPILNAPRTSFTESKGK---CNSWTSGSQGFLVVGFQNLNNARLVWIGSSDFLKNK----------------NQDSNQEFAKELLKWTFNEKSVIKSVHAVHSHADGTSYDEEPYKIKDKVIYSVGFSEWNGEEWLPHIADDIQFELRQVDPYYRLTLSPSGNDSETQYYTTGEFILPDRHGVFTFLTDYRKIGLSFTTDKDVKAIRHLANDEYPRSWEISNSWVYISAICGVIVAWIFFVVSFVTTSSVG--KKLETFKKTN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . .**** *: : :*::::.* :*.:.* : :... : *. : *:.::*:*.. . :::. :: *: : *.:. *.:* .* :.:* : .* *: . : .: *: . .: ::...::*:: . .: . .:: . :. :: :*.. *::: . : * :*:..:* ****::: ** *:.: . .* :.* : :*.* * . :: . * . .*.:.* * * : :. :* .. ..***:*: ::**: * *. . :* :** :**: * .**.::* :. .. ::* * : :* * *..:: * :: .:: . :.* . *: :*::", "identical_positions": 72, "similar_positions": 164, "identity": "14.91%" }, { "cls_id": "homologset.agr.MGI:1194513", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O55234-1", "uniprot_id": "PSB5_MOUSE", "id": "O55234-1", "name": "Proteasome subunit beta type-5", "aln": "-MALASVLQRPMPVNQHGFFG--LGGGADLLDLGPGSPGDGLSLAAPSWGVPE-----------EP--RIEMLHGTTTLAFKFLHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLLARQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWDKR-GPGLYYVDSEGNRISGTAFSVGSGSVYAYGVMDRGYSYDLKVEEAYDLARRAIYQATYRDAYSGGAVNLYHVREDGWIRVSSDNVADLHDKYSSV--------SVP-------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P28075-1", "uniprot_id": "PSB5_RAT", "id": "P28075-1", "name": "Proteasome subunit beta type-5", "aln": "-MALASVLQRPMPVNQHGFFG--LGGRADLLDLGPGSPGDGLSLAAPSWGVPE-----------EP--RIEMLHGTTTLAFKFQHGVIVAADSRATAGPYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLLARQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWDKR-GPGLYYVDSEGNRISGTAFSVGSGSVYAFGVMDRGYSYDLQVEEAYDLARRAIYQATYRDAYSGGAVNLYHVREDGWIRVSSDNVADLHDKYTS---------SIP-------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P28074-1", "uniprot_id": "PSB5_HUMAN", "id": "P28074-1", "name": "Proteasome subunit beta type-5", "aln": "-MALASVLERPLPVNQRGFFG--LGGRADLLDLGPGSLSDGLSLAAPGWGVPE-----------EP--GIEMLHGTTTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLLARQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWDKR-GPGLYYVDSEGNRISGATFSVGSGSVYAYGVMDRGYSYDLEVEQAYDLARRAIYQATYRDAYSGGAVNLYHVREDGWIRVSSDNVADLHEKYSG---------STP-------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P30656-1", "uniprot_id": "PSB5_YEAST", "id": "P30656-1", "name": "Proteasome subunit beta type-5", "aln": "MQAIADSFSVPNRLVKELQYDNEQNLESDFVTGASQFQRLAPSLTVPPIASPQQFLRAHTDDSRNPDCKIKIAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYHVTEDGWIYHGNHDVGELFWKVKEE--------EGSFNNVIG-------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9W1S5-1", "uniprot_id": "Q9W1S5_DROME", "id": "Q9W1S5-1", "name": "Proteasome subunit beta", "aln": "-MALEAICGMNKMPFMRRFDDLQSEWQKEQLREATSNFENPYELMAPPFERPAE---NLPKILSHCGIRMDFDHGTTTLGFKYRGGVILCADSRATSGQYIGSQTMRKIVELNDYMLGTLAGGAADCVYWDRVLAKECRLHQLRYRKRMTVDTAARIICNISTEYKGMGLVMGMMLAGFDDE-GPKLIYVDSEGMRSHGQVFSVGSGSPYALGVLDTGYRYDLSDQEAYDLARRAIYHATSKDAYSGGIVRLYHIHSEGWRNICNTDCSDLHDSYCASGCPGNEKDVGNVGDPDNDKPCSSGWTKKNITADNLQTKLATV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8INY4-1", "uniprot_id": "Q8INY4_DROME", "id": "Q8INY4-1", "name": "Proteasome subunit beta", "aln": "-MALESICGMDKLPFMKSFGYRTSKQTIEEIRVASSNMDNPLAIMAPPYENPRE---SVKKLNALSEVQIDFDHGTTTVGFVYQGGIILCVDSRATSGKLIGSQSIHKVVQVNQYIMGTTAGGAADCTYWDRALTRECRLHELRYKERLPVQSAAKYISNVAAEYKGMGLCMGMMLAGWSPE-GPSLVYVDSNGLRIHGKLFAVGSGAPNALGILDSDYRLDLSDNEAYDLAFLAVYHATMTDIFSGGVVRLYHMDQGNWRNVANKDCQELHEQYSG---------VGNQQTP---------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: . : : .. : .* * :.: *****:.* : *:*:..*****:* :.**:::*::::* :::** ******* :*: * :**:::** ::*:.* :*:: :.*: :*** ** ** *:.*: . ** : ****:* * * *.**** * *::* .* **. ::* *. :: *: * :*** *.***: . .* . : :*. . ", "identical_positions": 82, "similar_positions": 75, "identity": "25.62%" }, { "cls_id": "homologset.agr.MGI:1194881", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P55054-1", "uniprot_id": "FABP9_RAT", "id": "P55054-1", "name": "Fatty acid-binding protein 9", "aln": "MIEPFLG-TWKLVSSENFENYVRELGVECEPRKVACLIKPSVSISFNGERMDIQAGSACRNTEISFKLGEEFEETTADNRKVKSLITFEGGSMIQIQRWLGKQTTIKRRIVD---------------GRMVVECTMNNVVSTRTYERV------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O08716-1", "uniprot_id": "FABP9_MOUSE", "id": "O08716-1", "name": "Fatty acid-binding protein 9", "aln": "MIEPFLG-TWKLISSENFENYVRELGVECEPRKVACLIKPSVSISFNGERMDIQAGSACRNTEISFKLGEEFEETTADNRKVKSLITFEGGSMIQVQKWLGKQTTIKRKIVD---------------GKMVVECTMNNVVSTRIYERV------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q0Z7S8-1", "uniprot_id": "FABP9_HUMAN", "id": "Q0Z7S8-1", "name": "Fatty acid-binding protein 9", "aln": "MVEPFLG-TWKLVSSENFEDYMKELGVNFAARNMAGLVKPTVTISVDGKMMTIRTESSFQDTKISFKLGEEFDETTADNRKVKSTITLENGSMIHVQKWLGKETTIKRKIVD---------------EKMVVECKMNNIVSTRIYEKV------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8INK3-1", "uniprot_id": "Q8INK3_DROME", "id": "Q8INK3-1", "name": "Fatty acid-binding protein, muscle", "aln": "--MSFVGKKYKLDKSENFDEYMKELGVGLVTRKMGNSLSPTVEVTLEGDTYTLTTTSTFKTSAISFKLGVEFDEETLDGRNVKSIITLDGNKLTQEQKGD-KPTTIVREFTDNELITLIPHLTPSQHGSLRLRVPCQPVPPTSVDDGARSGGCGQRPGGP", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .*:* .:** .****::*::**** .*::. :.*:* ::.:*. : : *: : : ****** **:* * *.*:*** **::...: : *: * *** *.:.* : :. : : .* : . ", "identical_positions": 43, "similar_positions": 48, "identity": "26.88%" }, { "cls_id": "homologset.agr.MGI:1194883", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O43186-1", "uniprot_id": "CRX_HUMAN", "id": "O43186-1", "name": "Cone-rod homeobox protein", "aln": "--------------MMAYMNPGPHYSVNALALSG---------PSVDLMHQAVPYPS-----APRKQRRERTTFTRSQLEELEALFAKTQYPDVYAREEVALKINLPESRVQVWFKNRRAKCRQQRQQQKQQQQPPGGQAKARPAKRKAGTSPRPSTDVCPDPLGISDSYSPPLPG-----------------------------------PSGSPTTAVATVSIWSPASESPLPEAQRAGLVASGPSLTSAPYAMTYA---------------PASAFCSSPSAYGSPSSYFSGLD--PYLSPMVPQLG--------------------------------------------------------------------------------------------GPALSPLSG--------PSVGPSLAQSPTSLSGQSYGA----YSPVDSLEFKDPTGTWKFTYNPMDPLDYKDQSAWKFQIL-----------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O54751-1", "uniprot_id": "CRX_MOUSE", "id": "O54751-1", "name": "Cone-rod homeobox protein", "aln": "--------------MMAYMNPGPHYSVNALALSG---------PNVDLMHQAVPYSS-----APRKQRRERTTFTRSQLEELEALFAKTQYPDVYAREEVALKINLPESRVQVWFKNRRAKCRQQRQQQKQQQQPPGAQTKARPAKRKAGTSPRPSTDVCTDPLGISDSYSPSLPG-----------------------------------PSGSPTTAVATVSIWSPASEAPLPEAQRAGLVASGPSLTSAPYAMTYA---------------PASAFCSSPSAYASPSSYFSGLD--PYLSPMVPQLG--------------------------------------------------------------------------------------------GPALSPLSG--------PSVGPSLAQSPTSLSGQSYST----YSPVDSLEFKDPTGTWKFTYNPMDPLDYKDQSAWKFQIL-----------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9WTQ9-1", "uniprot_id": "Q9WTQ9_RAT", "id": "Q9WTQ9-1", "name": "Cone-rod homeobox protein", "aln": "--------------MMTYMNPGPHYSVNALALSG---------PSVDLMHQAVPYSS-----APRKQRRERTTFTRSQLEELEALFAKTQYPDVYAREEVALKINLPESRVQVWFKNRRAKCRQQRQQQKQQQQPPGVQAKARPAKRKAGTSPRPSTDVCTDPLGISDSYSPSLPG-----------------------------------PSGSPTTAVATVSIWSPASESPLPEAQRAGLVASGSSLTSAPYAMTYA---------------PASAFCSSPSAYASPSSYFSGLD--PYLSPMVPQLG--------------------------------------------------------------------------------------------GPALSPLSG--------PSVGPSLAQSPTSLSGQSYST----YSPVDSLEFKDPTGTWKFTYNPMDPLDYKDQSAWKFQIL-----------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8JIZ3-1", "uniprot_id": "Q8JIZ3_DANRE", "id": "Q8JIZ3-1", "name": "", "aln": "--------------MMSYIKQ-PHYAVNGLTLSA---------SGMDLLHTAVGYPA-----TPRKQRRERTTFTRTQLDILEALFTKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQ------QQQTSG-QPKPRPPKKKS--SPPP--DLTSDPGTSSSVVAAPTPT-----------------------------------VPPSVSAGTAPVSVWSPTSLSPLPDPLCG--SGTPCVQRPAPYPMSYG---------------QPSSYSQG---YGS-SPYFSGLDCSPYLSPMTTQLSAS------------------------------------------------------------------------------------------GGALSPLTV--------PSMGGSLSQSP-SLSSQGYSTASLGFSSVDCLDYKDQQ-AWKLNFSTVDCLDHK------FQVL-----------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P22810-1", "uniprot_id": "HMOC_DROME", "id": "P22810-1", "name": "Homeotic protein ocelliless", "aln": "MAAGFLKSGDLGPHPHSYGGPHPHHSVPHGPLPPGMPMPSLGPFGLPHGLEAVGFSQGMWGVNTRKQRRERTTFTRAQLDVLEALFGKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQLQQQQQSNSLSSSKNASGGGSGNSCSSSSANSRSNSNNNGSSSNNNTQSSGGNNSNKSSQKQGNSQSSQQGGGSSGGNNSNNNSAAAAASAAAAVAAAQSIKTHHSSFLSAAAAAASGGTNQSANNNSNNNNQGNSTPNSSSSGGGGGSQAGGHLSAAAAAAALNVTAAHQNSSPLLPTPATSVSPVSIVCKKEHLSGGYGSSVGGGGGGGGASSGGLNLGVGVGVGVGVGVGVSQDLLRSPYDQLKDAGGDIGAGVHHHHSIYGSAAGSNPRLLQPGGNITPMDSSSSITTPSPPITPMSPQSAAAAAHAAQSAQSAHHSAAHSAAYMSNHDSYNFWHNQYQQYPNNYAQAPSYYSQMEYFSNQNQVNYNMGHSGYTASNFGLSPSPSFTGTVSAQAFSQNSLDYMSPQDKYANMV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* **::* .*. .: ** :. .************:**: ***** **:***:: ***************************** .:. .. : . . :: *. . .: *. . . . * ::..*... .. : *. . . .: . . . .... .. .: . : : * *.. ...:. * ::*: *.: .**. : : . .: .*.... : . :::: .. : : : ", "identical_positions": 73, "similar_positions": 97, "identity": "13.47%" }, { "cls_id": "homologset.agr.MGI:1194884", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O08719-1", "uniprot_id": "EVL_RAT", "id": "O08719-1", "name": "Ena/VASP-like protein", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MFAF---EEFSEQSICQARASVMVYDDTSKKWVPIKPGQQGFSRINIYHNTASNTFRVVGVKLQDQQVVINYSIVKGLKYNQATPTFHQWRDARQVYGLNFASKEEATTFSNAMLFALNIMN----SQEGGPSTQRQVQNGPS------PEEMDIQRR------QVMEQ--QHRQESLERRIS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ATGPILPPGHPSSAASAT-------FSCSGPPPPP-----PPPVPPPPTGSTPPPPPPLPAGGAQGT---NHDESSASGLAAALAGAKLRRVQRPEDASGGSSPSGTSKSDANRAS---SGGGGGGLMEEMNKLLAKRRKAASQTDKPADRKEDENQTEDPSTSPSPGSRATSQPPNSSEAGRKPWERSNSVEKPVSSLLSRTPSVAKSPEAKSPLQSQPHSRVKPAGSVNDVGLDALDLDRMKQEILEEVVRELHKVKEEIIDAIRQELSGISTT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70429-1", "uniprot_id": "EVL_MOUSE", "id": "P70429-1", "name": "Ena/VASP-like protein", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSEQSICQARASVMVYDDTSKKWVPIKPGQQGFSRINIYHNTASSTFRVVGVKLQDQQVVINYSIVKGLKYNQATPTFHQWRDARQVYGLNFASKEEATTFSNAMLFALNIMN----SQEGGPSTQRQVQNGPS------PEEMDIQRR------QVMEQ--QHRQESLERRIS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ATGPILPPGHPSSAASTT-------LSCSGPPPPP-----PPPVPPPPTGSTPPPPPPLPAGGAQGT---NHDESSASGLAAALAGAKLRRVQRPEDASGGSSPSGTSKSDANRAS---SGGGGGGLMEEMNKLLAKRRKAASQTDKPADRKEDESQTEDPSTSPSPGTRATSQPPNSSEAGRKPWERSNSVEKPVSSLLSRTPSVAKSPEAKSPLQSQPHSRVKPAGSVNDVGLDALDLDRMKQEILEEVVRELHKVKEEIIDAIRQELSGISTT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UI08-1", "uniprot_id": "EVL_HUMAN", "id": "Q9UI08-1", "name": "Ena/VASP-like protein", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSEQSICQARASVMVYDDTSKKWVPIKPGQQGFSRINIYHNTASNTFRVVGVKLQDQQVVINYSIVKGLKYNQATPTFHQWRDARQVYGLNFASKEEATTFSNAMLFALNIMN----SQEGGPSSQRQVQNGPS------PDEMDIQRR------QVMEQHQQQRQESLERRTS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ATGPILPPGHPSSAASAP-------VSCSGPPPPP-----PPPVPPPPTGATPPPPPPLPAGGAQGS---SHDESSMSGLAAAIAGAKLRRVQRPEDASGGSSPSGTSKSDANRAS---SGGGGGGLMEEMNKLLAKRRKAASQSDKPAEKKEDESQMEDPSTSPSPGTRAASQPPNSSEAGRKPWERSNSVEKPVSSILSRTPSVAKSPEAKSPLQSQPHSRMKPAGSVNDMALDAFDLDRMKQEILEEVVRELHKVKEEIIDAIRQELSGISTT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B578-1", "uniprot_id": "A0A8M2B578_DANRE", "id": "A0A8M2B578-1", "name": "Ena/VASP-like protein", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDAHSVQFCLPQSHSDSGLHTSG---CKISEQSICQARASVMIYDDTSKKWVPVKPGQQGFSRINIYHNTVNNSFRVVGVKLQDQQVVINYSIVKGLKYNQATPTFHQWRDARQVYGLNFASKEEATTFSTAMLFALNVLG----SQDAGPGAHR--QNGPV------TDDGEAQRR------QMMDQ--HQMQMERERRTSGSAVSTLQFKVSASASQSETSLHDLRQYRANTLPPSYAHLNPAASSAHTAIPPLQEGGYHMVDSPQKKAQQLSQLSTSLASAFSPVQQGVVPPPRNIKQIPLSPPTSQQDLKHATWSSAHMYAPLPAASPPVVMAVKQPGLPVALPLPPLNNGPKAPSNTSHLDPIMHLQQSSNGQAEECYPYQSPSGGPLHPHYPIQESSCPLPPLIGQPVQGPGLHPQQLYQTTPPFETTPTSHTTPKTSPSPVYQNAAAASTGPPVPPGHPSMLSAAPPVHPPTSASMVGPPAPP-----PPPGPPPPGPPPPGPPPPVTGPPPTPPPLPAGGGPAPSGLAAALAGAKLRKVQRPEESSSSSNNSSNSKNDASRSSGG-SGGGGEGLMQEMNALLARRRKAS---EKPED-----SQNEESNGSPS------SSRGQNSDPVKKPWERANSADK-----------------------SSAVSRAKPLGSTSDA--ESFDFDRMKQEILEEVVRELQKVKEEIIDAIRRELLRIGST", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8T4F7-4", "uniprot_id": "ENA_DROME", "id": "Q8T4F7-4", "name": "Protein enabled", "aln": "MAMKKLYAKTSFTSKKPSSAANSTPILAYHQQQHQQPGNGICEFQVVAPGHSGELMIRRSQSMHHKMSPPVGGLGSKSEYYSIEELQELDLLDYRHPMYHHYQQQELRQRYHEHEQLVLQLPKATSPKAGPIYEAPQRSQQQQDQMLYVPTAAQRDSSSSAAATSIASSSTLTSSPSPSSSSSLIFSTLRKCVSPSNPSVNPNQPSKTQPSKLGCSMSFSIRTTTATAATAAAANAATATLSTQQQQQQAQQQHKQHLYSNIHHYLIRQQQQKQHYTLQRRHNSVKDKFIGGITTIFAEQSIIGARASVMVYDDNQKKWVPSGS-SSGLSKVQIYHHQQNNTFRVVGRKLQDHEVVINCSILKGLKYNQATATFHQWRDSKFVYGLNFSSQNDAENFARAMMHALEVLSGRVANNPGGPPTNGNGYEEDMGYRTMTSEDAAILRQNNSIGGHVTPSAQTPTSQTNQNNIPQSPPTPQGHHRTSSAPPAPQPQQQQQQQQAQQMGQPGSHYGPTGNGPTSNGLPQQVNSQIPPAPQQQPQQQQFQQQQQQQQYQQMVQAGYAPSQQYQQPHYVLSNSNPNLTVHQYPTQQAQQQPPQAPQPPLQNGGMYMVGHGHLP-------SSASANSVVYASQQQMLPQAHPQAPQAPTMPGPGYGGPPVPPPQQQAENPYGQVPMPPPMNPSQQQQPGQVPLNRMSSQGGPGGPPAPAPPPPPPSFGGAAGGGPPPPAPPQMFNGAPPPPAMGGGPPPAPPAPPAMGGGPPPAPGGPGAPPPPPPPPGLGGAPKKE---DPQADLMGSLASQLQQIKLKKNKVTTSAPENSGSSTSSGGSGNYGTIGRSSNGMASMMDEMAKTLARRRAQAEKKDPDPEAEVKKRPWEKSNTLPHK-----LSGGAGSGSAGSGHEGANGNSGGAGSNTTNSGGESPRPMRKRFGSASEETILKVNGDGLSLALSNGDLDTLKAEIVREMRLEIQKVKNEIIDAIKSEFNRR---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::**** ******:***..***** . ..*:*:::***: ..:***** ****::**** **:*********.*******:: ******:*:::* .*: **:.**:::. .: .** :: : .:: *: :: . . :.. . : * **. *. .:. . .**.** *** * * ..* **** . . ..**: : **:: : . .:. .*. * .* .... .: *..* .:*:** **:** : : : *... * . .* . . * :*. . :. : * *. . . *:* :* **:.*: *::***:******: *: ", "identical_positions": 128, "similar_positions": 120, "identity": "12.81%" }, { "cls_id": "homologset.agr.MGI:1194891", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P35053-1", "uniprot_id": "GPC1_RAT", "id": "P35053-1", "name": "Glypican-1", "aln": "----------------MELRARGWWLLCA-----------------------------AAALVACTRGD---PASKSRSCSEVRQIYGAKGFSLSDVPQAEISGEHLRICPQG--YTCCTSEMEENLANHSRMELETALHDSSRALQATLATQLHGIDDHFQRLLNDSERTLQDAFPGAFGDLYTQNTRAFRDLYAELRLYYRGANLHLEETLAEFWARLLERLFKQL--HPQLLLPDDYLDCLGKQAEALRPFGDAPRELRLRATRAFVAARSFVQGLGVASDVVRKVAQVPLAPECSRAVMKLVYCAHCRGVPGARPCPDYCRNVLKGCLANQADLDAEWRNLLDSMVLITDKFWGPSGAEYVIGSVHMWLAEAINALQDNKDTLTAKVIQGCGN--PKVNPHGSGPEEK----------------------------------------------------------------------------------RRRAKLALQEKSST----GTLEKLVSEAKAQLRDIQDYWISLPGTLCSEK-MAMSPASDDRCWNGISKGRYLPEVMGDGLANQINNPEVEVDITKPDMTIRQQIMQLKIMTNRLRGAYGGNDVDFQDASDD---GSGSGSGGGCPDD----------------------------------------ACGRRVSKKSS-SSRTPLIHALPGLSE------------------------QEGQKTSAATRPEPHYFFLLFLFTLVLAAARPRWR---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QZF2-1", "uniprot_id": "GPC1_MOUSE", "id": "Q9QZF2-1", "name": "Glypican-1", "aln": "----------------MELRTRGWWLLCA-----------------------------AAALVVCARGD---PASKSRSCSEVRQIYGAKGFSLSDVPQAEISGEHLRICPQG--YTCCTSEMEENLANHSRMELESALHDSSRALQATLATQLHGIDDHFQRLLNDSERTLQEAFPGAFGDLYTQNTRAFRDLYAELRLYYRGANLHLEETLAEFWARLLERLFKQL--HPQ-LLPDDYLDCLGKQAEALRPFGDAPRELRLRATRAFVAARSFVQGLGVASDVVRKVAQVPLAPECSRAIMKLVYCAHCRGVPGARPCPDYCRNVLKGCLANQADLDAEWRNLLDSMVLITDKFWGPSGAESVIGGVHVWLAEAINALQDNKDTLTAKVIQACGN--PKVNPHGSGPEEK----------------------------------------------------------------------------------RRRGKLALQEKPST----GTLEKLVSEAKAQLRDIQDFWISLPGTLCSEK-MAMSPASDDRCWNGISKGRYLPEVMGDGLANQINNPEVEVDITKPDMTIRQQIMQLKIMTNRLRGAYGGNDVDFQDASDD---GSGSGSGGGCPDD----------------------------------------TCGRRVSKKSS-SSRTPLTHALPGLSE------------------------QEGQKTSAATCPEPHSFFLLFLVTLVLAAARPRWR---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P35052-1", "uniprot_id": "GPC1_HUMAN", "id": "P35052-1", "name": "Glypican-1", "aln": "----------------MELRARGWWLLCA-----------------------------AAALVACARGD---PASKSRSCGEVRQIYGAKGFSLSDVPQAEISGEHLRICPQG--YTCCTSEMEENLANRSHAELETALRDSSRVLQAMLATQLRSFDDHFQHLLNDSERTLQATFPGAFGELYTQNARAFRDLYSELRLYYRGANLHLEETLAEFWARLLERLFKQL--HPQLLLPDDYLDCLGKQAEALRPFGEAPRELRLRATRAFVAARSFVQGLGVASDVVRKVAQVPLGPECSRAVMKLVYCAHCLGVPGARPCPDYCRNVLKGCLANQADLDAEWRNLLDSMVLITDKFWGTSGVESVIGSVHTWLAEAINALQDNRDTLTAKVIQGCGN--PKVNPQGPGPEEK----------------------------------------------------------------------------------RRRGKLAPRERPPS----GTLEKLVSEAKAQLRDVQDFWISLPGTLCSEK-MALSTASDDRCWNGMARGRYLPEVMGDGLANQINNPEVEVDITKPDMTIRQQIMQLKIMTNRLRSAYNGNDVDFQDASDD---GSGSGSGDGCLDD----------------------------------------LCSRKVSRKSS-SSRTPLTHALPGLSE------------------------QEGQKTSAASCPQPPTFLLPLLLFLALTVARPRWR---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PID2-1", "uniprot_id": "A0A8M1PID2_DANRE", "id": "A0A8M1PID2-1", "name": "Glypican-1", "aln": "------------MRSALDLIRTSRLFLLSR-------------------------MGFVALVLLCALTGLVFGDNKPKTCSDIRLFYSNKGFNLNGVPQTEISGEHLRVCAQG--YTCCTSVMEENLLNLSRREFETQVKESGRSLQAKLNGQFKSFDEYFLELLNRSEASLQSSFQSGFGSLFSQMSKVFQDLFSDLRRYFRGSNVNLEEALNEFWARLLDRLFKALNPQYS--IGEEYLECVAKQSEKLKPFGETPRELKTKITRTVIAARTFVQGLVISGEAVRKVSQVSLSTECVRAVMKQTYCPHCSGVALAKPCSNYCRNVLKGCLANQADLDTEWRNLADAMLEVVDKLSRPYSVDSVVLSLPKRIAEAILYMQDNQDMFINKVFLECG---TPAPSSNIQEQIK----------------------------------------------------------------------------------RGRNTAEEVSSTPG----AQLERLLSDVSRMLRDMMQYWVHLPRKLCVDR-ESGPGESD-RCWNGMSVGRYLPEVMGDGLASQINNPEVEIDITKPDMAVRKQIMQLKIMINRLKYAVNGNDVDFQDTSDD---ISGSGSG-MCLDD----------------------------------------QCSRG-PRLMSPNTDKPKVYASP----------------------------SENKKVVNGRSSQNLPCISLYLLSLVTVLLRR------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1QCC6-1", "uniprot_id": "GPC1_DANRE", "id": "F1QCC6-1", "name": "Glypican-1", "aln": "----------------MDLTAVALLVSL-------------------------------VSVSLSAEN----AGGKARSCTDVRQFYSGKGFTLNGVPQSEISGEHLRICPQG--YTCCTSAMEETLSNLSRREFEGLVREAGRSIQALLNAQYRTFDTYFLELLNGSERWLEEAFVAALGELYRLNAGVFRDLYAELHRYYSGASLNLEEALDEFWMKLLERLLKASDPETASLLSDDFLDCASKQTETLRPFGDAPRELKAKLVRAFIAARAFVQGLNAAGEIVRKVSQVPLSPECNRAIMKLVYCPHCRGLGSVKPCINYCKNVMKGCLANQADLDTEWQSLIETMLQVASSFGAEPSMDTVIYSIPVRISEAVLAMQENMEIYTSKVFKACGDRGEEGTPSSISEEPK----------------------------------------------------------------------------------KKERTVTALEYKPSPKSAARLEVQVTDVYSKLKEMQLYWIQLPSALCSGK-TASSTTGD-KCWNGITKASYLPEVMGDGLANQINNPEVEIDITKPDRTIRQQIMLLKIMSNRLKNALEGNDVDFQDTSDD---FSGSGSG-MCADH----------------------------------------LCVRGRPPVFGPKTDRPKLYATG----------------------------PENKRVK-GSGNQIQPSFILLIVFFVSLLLRR------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VUG1-1", "uniprot_id": "Q9VUG1_DROME", "id": "Q9VUG1-1", "name": "", "aln": "MLHQQQQQQHLHCRRKATATTTARLVIFSSPLLLLLLTTHLPPTLQADNGPAPQVAALAAPNPAGGVAGSSIIDQFSPNCSAVTHIFQARGIDAIEIPQKPSNERVLRYCESPSVGTCCTYNMETRMAMQSRQQLEGHTKDQISRMSGILGSKATKFKDIFTALLKESRTQFNSMFIRTYGVIYERNSYVFSDLFKELETYFANGRVDLLEVMDKFFNTLYQKMFTVLN--TQYTFDENYMRCVSEHMKELKPFGDVPDKLSVQIKRSFVATRTYGQALTTASEVAKKVLNVRLNADCTGALTKMQHCGACKGYT-EKPCTNYCVNVIKGCLHYQHEFDSEWENFAMAMDKVAERLLGSFNIVMVVEPLNIKISEAIMNFQDSGQDITNRVFQGCGRPKLKKMKRSISPKLQGVQILNARSPVEADTLDIDETLDEAIVLRERRAAEPGSQETSAQQSQEQGVGKSGNGGGGGGGNNRRQQQRRKQQQQRRKQQNNRDDNDDDDNESGGGREPILDRIVRDIRQRVKDYKKFWSNLPHSVCSNEDIASSSDVDGMCWNGHTIDRYMHSITTEHGSNPEFTG--NPASTKQTAQMASQLSHLKNAIVHLRNAYNGQDVEWSEQEELPYAGSGAGSGSGSEDDEDDDEGSGLGPFEPSHKPDVERPSVDADNDDDEDAGGRGHMPTHTSRPTSGVDDKNPLIHTTHFDQDHNDLDEDHRQLDEDEDTDAGHDGANDNRSSDAPEKMTLRRALVVYLLPLYMAWFGGVCADLL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . . .* : :: :*: :** . . ** * . **** ** : *: ::* :: :.. * : :. * **: *. :: * * :: : .* **: :*. *: .. :.* *.: :*: * ::::. : :::: * .:: : *:***:.* :* : *:.:*:*:: *.* :.: .:** :* * .:* *: * :* * * :** :** **:**** * ::*:**..: :* :.. : . *: : ::**: :*:. : :*: ** . : : . . . . *: : : ::: :* ** :* . : . * **** : *: .: : :. . : ** : .*: ** :*: * *:**::.: .: **:*** . *. : . . * :: :.: : :. : ", "identical_positions": 103, "similar_positions": 162, "identity": "13.38%" }, { "cls_id": "homologset.agr.MGI:1194894", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LRH5-1", "uniprot_id": "A0ABK0LRH5_RAT", "id": "A0ABK0LRH5-1", "name": "", "aln": "MLRKRSPASQPQGFRGESEALLGEAAVCSRSSRGRLRFEPSPDLARHHLPAPPMLGAPESGDHSGEGATRTPRMDARTWRLGWRCLLLLALLGSTRSEGVESCEEVRKLFQWRLGGAVKGLPEAPRAGPDLQVCLSKNPTCCTRKMEEQYQIAAQQDLQQVLQTSSSTLKLLISRNAAAFQETLETLIRQAENYTSILFCNTYRNMALEAAASTQEFFTDVGLYLFG------------------ADVNPEEFVNRFFDSLFPLVYNHLINPG---VTDSSLQYSECIRTARQDVSPFGNIPKRVMGQMGRSLLPGRTFLQALNLGIEVINTTDHIH---FSKECSRALLKMQYCPHCQSLTLS-----KPCMGYCLNVIRGCLAHMT-DLNPHWHAYIRSLEELS-DAMHGTYDVEHVLLNFHLLVNDAMLQAHLNAQKLLDQVNKICGLPVRTATQSPRCTFDPSKERHGMKISPRNGEETLANRRKEFINSLRLHRSFYGGLADQLCVNEWAAAEGRPCWNGEDIVKSYAQRVVGNGVKAQSANPEVRVRGTDP--VVNQIIDKLKHVIQLLQGRSP----KPNKWELLHPGSGGGMLEQSSGDCDDEDGCGGSGSGEVKRTLKITNWMPDSMNFSDVKQVHGADRGSTLDTTGAGCGSGTESMTLLLMGTLMFLPWLW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CAL5-1", "uniprot_id": "GPC5_MOUSE", "id": "Q8CAL5-1", "name": "Glypican-5", "aln": "-------------------------------------------------------------------------MDARTWRLGWRCLLLLALLGSTRSEGVESCEEVRKLFQWRLGGAVKGLPEAPRAGPDLQVCLSKNPTCCTRKMEERYQIAARQDLQQVLQTSSSTLKLLISRNAAAFQETLETLIRQAENYTSILFCNTYRNMALEAAASIQEFFTDVGLYLFG------------------ADVNPEEFVNRFFDSLFPLVYNHLINPG---VTDSSLQYSECIRMARQDVSPFGNIPKRVMGQMGRSLLPGRTFLQALNLGIEVINTTDHIH---FSKECSRALLKMQYCPHCQSLMLS-----KPCMGYCLNVIRGCLAHMT-ELNPHWHAYIRSLEELS-DAMHGTYDVEHVLLNFHLLVNDAVLQAHLNGQKLLDQVNTICGHPVRTPTQSPRCTFDPSKEKHGMKISARNGEETLANRRKEFINSLRLHGSFYGGLADQLCVNELAAPEGRPCWNGEEIVKSYAQRVVGNGIKAQSANPEVRVRGTDP--VVNQIIDKLKHVIQLLRGRSP----KPNKWELLQPGSGGGMLENSSGDCDDEDGCGGSGSGEVKRTLKITNWMPDSMNFSDVKQVHRADHGSTLDTTSTGCASGTESMALPLMGTLMFLPWLW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P78333-1", "uniprot_id": "GPC5_HUMAN", "id": "P78333-1", "name": "Glypican-5", "aln": "-------------------------------------------------------------------------MDAQTWPVGFRCLLLLALVGSARSEGVQTCEEVRKLFQWRLLGAVRGLPDSPRAGPDLQVCISKKPTCCTRKMEERYQIAARQDMQQFLQTSSSTLKFLISRNAAAFQETLETLIKQAENYTSILFCSTYRNMALEAAASVQEFFTDVGLYLFG------------------ADVNPEEFVNRFFDSLFPLVYNHLINPG---VTDSSLEYSECIRMARRDVSPFGNIPQRVMGQMGRSLLPSRTFLQALNLGIEVINTTDYLH---FSKECSRALLKMQYCPHCQGLALT-----KPCMGYCLNVMRGCLAHMA-ELNPHWHAYIRSLEELS-DAMHGTYDIGHVLLNFHLLVNDAVLQAHLNGQKLLEQVNRICGRPVRTPTQSPRCSFDQSKEKHGMKTTTRNSEETLANRRKEFINSLRLYRSFYGGLADQLCANELAAADGLPCWNGEDIVKSYTQRVVGNGIKAQSGNPEVKVKGIDP--VINQIIDKLKHVVQLLQGRSP----KPDKWELLQLGSGGGMVEQVSGDCDDEDGCGGSGSGEVKRTLKITDWMPDDMNFSDVKQIHQTDTGSTLDTTGAGCAVATESMTFTLISVVMLLPGIW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q24114-1", "uniprot_id": "DALY_DROME", "id": "Q24114-1", "name": "Division abnormally delayed protein", "aln": "-------------------------------------------MAARSVRLAQLLLFTLLCGFVGLSAAKHLDLDGIHHHQHHLHSATTHHRRRLQRDSRAKDAVGGSTHQCDAVKSYFESIDIKSSGTYSEKGAICGGNCCNNATELELRDKAAGMFEQLLHHHTSSLRGVLETNAKQFQSHVLELAQISENMTHSLFSKVYTRMVPSSRMMIHQLYTEIMNHLIYTSNYTNSNGQLGRRGIGSVQSNLEEAVRHFFVQLFPVAYHQMVHLSKNNLGDLHEDYVNCLQHNFDEMHPFGDIPQQVQSNLGKSVHMSNVFMNALLQAAEVLSEADALYGEQLTDTCKLHLLKMHYCPNCNGHHSSSRSETKLCYGYCKNVMRGCSAEYAGLLDSPWSGVVDSLNNLVTTHILSDTGIINVIKHLQTYFSEAIMAAMHNGPELEKKVKKTCGTPSLTPYSSGEPDARPPPHKNNVKWATDPDPGMVL-----FLSTIDKSKEFYTTIVDNFCDEQQHSRDDHSCWSG-DRFGDYTQLLINPGTDSQRYNPEVPFNAKAQTGKLNELVDKLFKIRKSIGAAAPSNSIQATHDIQNDMGEGSGGGEGQIGDDEEEYG-GAHGSGDGS-----GDGPHTPIEESEGTTTNEVESRDSGKTSGSNPLEGTATWMLLTLVTMLFSSCS-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*. : :. . . .* : : :*. : .**.. * . : * ::*.*: :*:*: ::. ** **. : * : :** * **...* .*. .: ::::*:: :*: .: * ** *.:** .***:.*::::: . : * :* :*:: :: ***:**::* .::*:*: ...*::** . **:. :* :: ::. *. ****:***:*:. : * * *** **:*** *. : *:. * . : **::* : . .: :*: ::: ..:*:: * *. :* .:*: ** * *. .* . . .::.:* :. . : *:.:: .** :.*::* :: : :. .**.* : . .*:* ::. * .:* **** ... :*:::*** :: : : . :* :. : . *.*.* * ** ::* * *. ***: . : :: *: . : .: .: .*:.:. .* : : : .::: . ", "identical_positions": 125, "similar_positions": 209, "identity": "18.33%" }, { "cls_id": "homologset.agr.MGI:1194898", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A5T8-1", "uniprot_id": "D4A5T8_RAT", "id": "D4A5T8-1", "name": "Periplakin", "aln": "------MHSLFRKKNKGKYSPTVQTRSIS--NKELSDLIEQLQKNADQVERNIVDTEAKMQSDLARMQDGQLPEHRDATLQNVSDSEKLLYVLEADSAIAKHMKHPQGDMIAEDIRQLKERVTNLRGKHKQMYSLAVREADPKVNWDALVDEKLDKLSSQSFGTDLPLVDSQVEQHNIFHNEVKAIGPHLAKD--KEQNSELQAKYQKLLAASQARQQHLSSLQDYMQRCTNELYWLDQQAKGRIQYDWSDRNLDYPSRRRQYENFINRNLEAKEERINKLHTEGDQLLTAEHPGRNSIEAHMEAVHAEWKEYLNLLICEESHLKYMEDYHQFHKDMKDAQELLRKVDSDLNQKYSPDFKDRYQIELLLRELDDQEKALDKYEDVVRGLQKRGQQVLPLKYRRETPLKPIPVEALCDFEGDQGLISRGYSYTLQKNNGESWELTDSTGKKLMAPAVCFIIPPTDPEALALSDSLGSQYRSVRQKAAGSKHALQQRHEVLRTENPG--DASDLQGRQLLAGLDQVASDLDRQEKAITGILRPPLEQGRAIEDSAERAKHLKNITNELLQIEPEKIQRTAECEAFVQALPGSGTTPLLKTRVEDTNQKYKRLVQLLEAAQEKVDVANRLENSLQRGRELLASHENRLMQDDTIPESDYMLDSKRQELEAMASELQAQKSLLGEVEQNLQVAKQCSSSLASRFQEHCPDLERQEAEVHKLNQRFNNLNQQVERRAQSLQSARDAYSEYCRGYDHVLQFLVKTPSYEPQETDSLSQMETKLKNQKNLLDEIASMEQGAQKVYADSQQYQQAVKDYELEAEKLRSLLDLENGRNSHVNKRARLQSPAAKVKEEEAALAAKFTEVNAINRQRLQNLEFALNLLRQQPEAGVTHETLQGREQGSGMEETWKIQKELEEEMERRQQLENEVKSAQEEIQTLKDQGPQESLVRKEVLKKVPDPALEESFQQLQQTLAEEQHKNQLLQEELGALQLRLQALEQETRDGGQEYVVKEVLRIEPDRAQEDEVLQLREELEGLRRQKGAREAEVLLLQQRVAALAAEKSRVQEKVTEREVVKLQNDPQLEAEYRRLQEEHQREGTLREKQEEELSFLQAKLRRLEKERAMAEGKITVKEVLKVEKDTAAEREVNDLSRQYEDEASKARTSQREKTELLRKIWALEEENAKVVVQEKVREIVRPDPKAESEVANLRLELVEQERKFRGAEEQLKSYQSELEALRNRGPQVEVKEVTKEVIKYTTDPETEQELQRLREEIMDKTRLIERCDLEIYQLKQEIQILKDTKPQVQTREVVQEILQFQEDPQTKKEVESLRIQLSEEKKKLVDLEGEQASQEEKIKRKEEELAQ-GKERIVRQEVVQYEDEPDLRAEVTAFTDSIDVELRQIDKLCVELRRLQHRRAELERQLEELERERQARRAAELEVQRLQQRLAALEQEEAKTGEKVTHTQKVVLQQDPQQTREHALLRAQLEEERHRRQLLEGELEPLRRKLAALEKTEIKEKVVFSESVQVEKG-DTEQEIQRLKKSLEEESRSKRELDSEVTRLEAKLSELEFYNSKSSKELDFLREENHKLQLERQNLQLETRRLQSEIEMAATETRDLKNITMVDSGTHLNSRLWSLEKELDDLKKMSKDKDLEIDELQRRLGSVAVKREQRENHLRRSIVVIDPDTGRELSPEEAHRAGLIDWKMFVKLRSQECDWEEISVKGPNGESSVIHDRKSGKKFSIEDALQSGRLTPAQYDRYVNKDMSIQELAVLVSGQK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R269-1", "uniprot_id": "PEPL_MOUSE", "id": "Q9R269-1", "name": "Periplakin", "aln": "------MHSLFRKRNKGKYSPTVQTRSIS--NKELSDLIEQLQKNADQVERNIVDTEAKMQSDLARMQEGQLPEHRDAALQNVSDSEKLLYVLEADSAIAKHMKHPQGDMIAEDIRQLKERVTNLRGKHKQMYSLAVKEADPRVNWDTLVDEKLDKLSSQSFGTDLPLVDSQVEQHNIFHNEVKAIGPHLAKD--KEQNSELQAKYQKLLTASQARQQHLSSLQDYMQRCTNELYWLDQQAKGRMQYDWSDRNLDYPSRRRQYENFINRNLEAKEERINKLHTEGDQLLTAEHPGRNSIEAHMEAVHAEWKEYLNLLICEESHLKYMEDYHQFHKDMKDAQELLRKVDSDLNQKYSPDFKDRYQIELLLRELDDQEKALDKYEDVVRGLQRRGQQVVPLKYRRETPLKPIPVEALCDFESDQGLISRGYSYTLQKNNGESWELTDSTGKKLAAPAVCFIIPPTDPEALALADSLGSQYRSVRQKATGSKHALQQRHEVLRTENPG--DASDLQGRQLLAGLDKVASDLDRQEKAITGILRPPLEQGRAIEDSAERAKGLKNITNELLQIEPEKTQCTAECEAFVQALPASGTAPLLKTRVEDTNQKYERLVWLLEAAQEKVDVANRLENSLQRGRELLASYENRLIQDDTMPESGHVLDRKRQELEAMASELQAHKSLLGEVGKNLQVAKQCSSSLASRFQEHCPDLERQEAEVHKLNQRFNNLSQQVERRAQSLQSARAAYDEYCSGYNRVLQFLAKTPSYEPQETDSLGQMETKLKNQKNLLDELASREQEVQKVYADSQQYQQAVKDYELEAEKLRSLLDLENGRNSHVNKRARLQSPAAKVKEEEAALAAKFTEVNAINRQRLQNLEFALNLLRQQPEAGVTHETLQGGKLSSGMEETWKIKKELEEEIERRQQLENEVKSAQEEIQTLKDQGPQESLVRKEVLKKVPDPALEESFQQLQQTLAEEQHKNQLLQEELGALQLRLQALEQETRDGGQEYVVKEVLRIEPDRAQEDEVLQLREELEALRRQKGAREAEVLLLQQRVAALAAEKSRVQEKVTEREVVKLQNDPQLEAEYRRLQEEHQREGTLREKQEEELSFLQAKLRRLEKERAMAEGKITVKEVLKVEKDAAVEREVNDLTRQYEDEAAKARSGQREKTELLRKIWALEEENAKVVVQEKVREIVRPDPKAESEVANLRLELVEQERKFRGAEEQLKSYQSELEALRNRGPQVEVKEVTKEVIKYTTDPETEQELQRLREEIMDKTRLIERCDLEIYQLKQEIQALKDTKPQVQTREVVQEILQFQEDPQTKKEVESLRIQLSEEQKKQVDLEGERASQEEKIKRKEEELAQQRKERVVRQEVVQYEDEPDLRAEVTAFTNSIDAELRQIDKLHVELRRLQHRRAELERQLEELERERQARRAAELEVQRLQQRLAALEQEEAKTGEKVTHTQKVVLQQDPQQTREHALLRAQLEEERHRRQLLEGELEPLRRKLAALEKAEIKEKVVFSESVQVEKG-DTEQEIQRLKKSLEEESQSKRELDSEVTRLEAKLSELEFYNSKSSKELDFLREENHKLQLERQNLQLETRRLQSEIEMAATETRDLKNITTIDSGTHLNSRLWSLEKELDDLKKMSKDKDLEIDELQRRLGSVAVKREQRENHLRRSIVVIDPDTGRELSPEEAHRAGLIDWKMFVKLRSQECDWEEISVKGPNGESSVIHDRKSGKKFSIEDALQSGRLTAAQYDRYVNKDMSIQELAVLVSGQK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60437-1", "uniprot_id": "PEPL_HUMAN", "id": "O60437-1", "name": "Periplakin", "aln": "------MNSLFRKRNKGKYSPTVQTRSIS--NKELSELIEQLQKNADQVEKNIVDTEAKMQSDLARLQEGRQPEHRDVTLQKVLDSEKLLYVLEADAAIAKHMKHPQGDMIAEDIRQLKERVTNLRGKHKQIYRLAVKEVDPQVNWAALVEEKLDKLNNQSFGTDLPLVDHQVEEHNIFHNEVKAIGPHLAKDGDKEQNSELRAKYQKLLAASQARQQHLSSLQDYMQRCTNELYWLDQQAKGRMQYDWSDRNLDYPSRRRQYENFINRNLEAKEERINKLHSEGDQLLAAEHPGRNSIEAHMEAVHADWKEYLNLLICEESHLKYMEDYHQFHEDVKDAQELLRKVDSDLNQKYGPDFKDRYQIELLLRELDDQEKVLDKYEDVVQGLQKRGQQVVPLKYRRETPLKPIPVEALCDFEGEQGLISRGYSYTLQKNNGESWELMDSAGNKLIAPAVCFVIPPTDPEALALADSLGSQYRSVRQKAAGSKRTLQQRYEVLKTENPG--DASDLQGRQLLAGLDKVASDLDRQEKAITGILRPPLEQGRAVQDSAERAKDLKNITNELLRIEPEKTRSTAEGEAFIQALPGSGTTPLLRTRVEDTNRKYEHLLQLLDLAQEKVDVANRLEKSLQQSWELLATHENHLNQDDTVPESSRVLDSKGQELAAMACELQAQKSLLGEVEQNLQAAKQCSSTLASRFQEHCPDLERQEAEVHKLGQRFNNLRQQVERRAQSLQSAKAAYEHFHRGHDHVLQFLVSIPSYEPQETDSLSQMETKLKNQKNLLDEIASREQEVQKICANSQQYQQAVKDYELEAEKLRSLLDLENGRRSHVSKRARLQSPATKVKEEEAALAAKFTEVYAINRQRLQNLEFALNLLRQQPEVEVTHETLQRNRPDSGVEEAWKIRKELDEETERRRQLENEVKSTQEEIWTLRNQGPQESVVRKEVLKKVPDPVLEESFQQLQRTLAEEQHKNQLLQEELEALQLQLRALEQETRDGGQEYVVKEVLRIEPDRAQADEVLQLREELEALRRQKGAREAEVLLLQQRVAALAEEKSRAQEKVTEKEVVKLQNDPQLEAEYQQLQEDHQRQDQLREKQEEELSFLQDKLKRLEKERAMAEGKITVKEVLKVEKDAATEREVSDLTRQYEDEAAKARASQREKTELLRKIWALEEENAKVVVQEKVREIVRPDPKAESEVANLRLELVEQERKYRGAEEQLRSYQSELEALRRRGPQVEVKEVTKEVIKYKTDPEMEKELQRLREEIVDKTRLIERCDLEIYQLKKEIQALKDTKPQVQTKEVVQEILQFQEDPQTKEEVASLRAKLSEEQKKQVDLERERASQEEQIARKEEELSR-VKERVVQQEVVRYEEEPGLRAEASAFAESIDVELRQIDKLRAELRRLQRRRTELERQLEELERERQARREAEREVQRLQQRLAALEQEEAEAREKVTHTQKVVLQQDPQQAREHALLRLQLEEEQHRRQLLEGELETLRRKLAALEKAEVKEKVVLSESVQVEKG-DTEQEIQRLKSSLEEESRSKRELDVEVSRLEARLSELEFHNSKSSKELDFLREENHKLQLERQNLQLETRRLQSEINMAATETRDLRNMTVADSGTNHDSRLWSLERELDDLKRLSKDKDLEIDELQKRLGSVAVKREQRENHLRRSIVVIHPDTGRELSPEEAHRAGLIDWNMFVKLRSQECDWEEISVKGPNGESSVIHDRKSGKKFSIEEALQSGRLTPAQYDRYVNKDMSIQELAVLVSGQK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58IPA3-1", "uniprot_id": "A0AC58IPA3_DANRE", "id": "A0AC58IPA3-1", "name": "", "aln": "MQTDVYLFGLLKVYQTALLKTNSLLFHLRPPETDLASLIDKLQRNADKVEKNIIETEQNLNKDIRKINEGKPPLYQEDTSKRIANSLDLLKSLDDDAALAVQLKHPQGEMIEKDMRQLRVRVMKLQDDHNRIYNTTRSEQVPTVNWGKMIDEKLANLNNKGFGQDLPTVENEVEEHNIFHSEVEALAPYVSGD--RDSLDGQQARYNRLLATSTARQKNLLSMRDYMQRCTNELYWMDQQAEERIAYDWSDNNLDYPARKRQYENFISKCLESKEKTVTQLNEDGEELIEQNHPGKNVIAAHMDAVHSDWKEYLNLLICEENHLKNMDDYHKFQKEARDTSDLMKRLETEINQKYNPEFKDMYQMEGLIADLDDQAKAMDHFDERLKNLQKRSLQVLPLKYRRETPQKLLPIEALCEYDAEEGSILRGERYTLLRNNGPKWDVKDANGRTMSAPGVCFIIPPTDPEAVASADNLINQHKSIKQKVASSKTALQARLAELKKESTGGADKQEQQCRQLMAGLDKVVSDLDKQEKAIYSRVRPPLEQTRPVQDSADRLQDIRDITSAVNKIEPEKSAKVKEAEAFLKSSPKCASAPQLYSKVDDTNKKYNKVDLLLKCSTDKLQNSYQLENSLQNGKTLLSTYENKLAREETAPSDPASIEKTQRELADIASELRSKRSIITQTEQNLRDAKTSCSNMTNKVQEHCPDIERQEAEVQKMTKRFDNLNRQTEARSQHLQRAKTAYSNYHNDYENLNSWLSRIPNYEPRETDDVRQIDSKLKNQRNLLSDIARKESDLNNVSRNAQLYQQAVKDYENEAERFKSILDLEDGLVPQTYKRSRLESPAMKVNREESAIEAKFTEVNAVNKQRLQNLEFAQSLLNQQPEVTIVRQDVQTVRSSAPGEEPWRIKNQLQEEIQRRDQLEREIQSVQSDIYFLEGQKPQDTIVKKELVKKVPDPQLDEEYHRVQQKLLDESRTTRILESELDTLRVKLRGIETEMKEGAQQYTVKEVLRIERDRGQEEELRRLREELEEVKRMKMVRENEIIQIRKQVTILAEEKSREQEIIKEEEVIKVQNDPQLESEYRVLLERKQKDIETRKELEDELRFLQERLRRLEKEKAMAEEKISIKEVLKVEKDIALEREVENLRRQYEDEKTRRSAALRERTDLQRKITSLEEEKSKVIIQEKVREIVRPDPKAETEVANLRLDLVEQQRRCRDSELQLRSLQDELTMLRNRGPQIEYKEIIKEVIKYKIDPQTERELEQLRNEIVDKTHQTERFEMEILQLKDEIQRWKDTKPQIQTKEVVNEILQYREDPKTKEEIESLKRKLAEEQRKRLELENERALSEEKIRIKKIDLSQ-VREKLVQQEVVKMELDPLLKSECDTFSLNISNEQKQREILKEELIRLQRQKTELDVQLEELERERRARRDAELEIQRLRVRLNELEIRDKENREKVTVKQKVVLQQDPQQEKEHSILRLQVEEERHKRMLLEKEFNALLQQQEILERTEVREKVVRTEKIQVERDPDAEMDIIRLKKSLEEEERRRRELDQEIVTLNTKLSEMEFTNTKSSKELDYIRDESNRLQQENQRLQNELRKLQSEIEITTTETRHITESSPVESSRNLEIRMESLQRELAELRRIRMEKDDEIEKLQKSLAAMRVKREQRESHLRRSIVVIDPDTGKEMKPEEAYKLGLIEWKMFVNLQSQECDWEEITVKGPSGESSVLHDRKSGKKFSIEDALKAGNITNRQLQQYQNKEISIQEFGVMLSGRGK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .*:: :.. ... : :.:*:.**::**:***:**:**::** :::.*: ::::*: * ::: : :.: :* .** *: *:*:* ::*****:** :*:***: ** :*:..*:::* : * * *** :::*** :*..:.** *** *: :**:*****.**:*:.*::: * ::. . :*:*::**::* ***::* *::************:****: *: *****.*****:*:*******.: **:**: :.:*: :*::*: :***:* * ***:***::************.*** *:***:*::: :*:.:*::::::::****.*:*** **:* *: :**** *.:*:::: ::.**:*. **:********* * :*:****:::.::* * ** *** :*** .*:: *: *..: **.***:********:* :*.* .*::*::**.:.** :** * *:.*..* * .: * ***:****:*.****:***** . :****** *.::***:* : :::**. : :***** . * ***::: * ..::* * ::*:***:**::: **. : :*:: : :**:***.. **:::**:* :::* *.. :: . :** :*.**::::*:: :. :**: ** ..*.::.:.******:*******:*: :**:** :*.* *:* ** *: **..: .::.: .:* *.***:***.: *:::*****:***.::* *. ::: ::* ********* ***:::*:****:* .:. **:**:*** **:.**:*: ****** *:*:********* .**.****. :.:: :* . .: **.*:*:::*:** :** ***.*::*.*.:* *..* **:::*:**::****** *:*.::::*:.* :*.:..::*:.** :*:::*:.:* * ::*.*:*.******** **.* :*: :****** ::* * .** *:: ::::*: ** **** ** :.*.**:*:*******:**: * * :*:: *:: *:** *** :*:*****:**** **::********* * ****.:* ****** :: :. **:*:* *** :****::**::***************:*******:****:*: *.:* **:* *.** **.****:* **: ******. **: *:**::**:**:***: ** ::** ***.*** ******:**:***:****::***:**:*: **: :*:**::* ::** *:* .**:* *: :*:: :*::*:****: * :* *::* :*: .*. * :* : * ** ***::::**: *********:*** ** *:***: ** ** .: : **** .*********** :**::** *:***:*:* *** *::.* :: **::*::**** :*.:***:. *:* :* ***.*****.: :**** *: *:::***:** *:*******::*:*.::** *.*.** * *:*****::::****.: : : :*. : : *: **::** :*::: :** **::**: *.:: *******.*********.****:*:.****:: ***:*:***:*:*********:****.*****:************:**::*.:* * ::* **::****:.*::**: ", "identical_positions": 888, "similar_positions": 583, "identity": "50.2%" }, { "cls_id": "homologset.agr.MGI:1194899", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K2Z2-1", "uniprot_id": "A0A0G2K2Z2_RAT", "id": "A0A0G2K2Z2-1", "name": "Inositol polyphosphate 5-phosphatase K", "aln": "-----------------------MTTASLRKPSA---------------------------------------------PKELMLSIHVVTWNVASAAPT-VDLSDLLQLN----------NEDLNLDIYIIGLQEMNYGIISLLSDAAFEDPWSSFFMDMLSPLNLVKISQVRMQGLLLLVFAKYQHLPYIQIISTKSIPTGLYGYWGNKGGINICLKLYGYYVSIVNCHLPPHMYNNDQRLEHFDRILESLTFEGYDVPNILDHDLILWFGDMNFRIEDFG-LLFVQECITK-KRYKELWEKDQLFIAKKQ-DQLLREFQEGPLLFPPTYKFDRHSNNYDT---------SEKKRKPAWTDRILWRLKRQPAKANPSG-----------------FLLTQKDYVSHMTYSISDHKPVTGTFDLELNPLMSVPLITMMPEYLWTKENDMLINYTSTPEFLSSPWDWIGLYKVGMRHINDYVSYVWVGDN-------------------------------------QVSRGNNPNQVYINISAIPDTEEQFLLCYYSNN----LHSIVGISQPFKIP------SGFFLREDTLSELEPQL------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C5L6-1", "uniprot_id": "INP5K_MOUSE", "id": "Q8C5L6-1", "name": "Inositol polyphosphate 5-phosphatase K", "aln": "--------MQHGDRNTPGYREGIMSAVSLRRPSA---------------------------------------------PKGFALSVHVVTWNVASAAPT-VDLSDLLQLN----------NQDLNLDIYIIGLQEMNFGIISLLSDAAFEDPWSSLFMDMLSPLNFVKISQVRMQGLLLLVFAKYQHLPYIQIISTKSTPTGLYGYWGNKGGVNVCLKLYGYYVSIINCHLPPHMYNNDQRLEHFDRILESLTFEGYDVPNILDHDLILWFGDMNFRIEDFG-LLFVQESITR-KYYKELWEKDQLFIAKKN-DQLLREFQEGPLLFPPTYKFDRHSNNYDT---------SEKKRKPAWTDRILWRLKRQPSQASPLASSVPTSY----------FLLTLKNYVSHMAYSISDHKPVTGTFDLELNPLMSVPLITMMPEHLWTMENDMLISYTSTPEFLSSSWDWIGLYKVGMRHINDYVAYVWVGDN-------------------------------------QVSYGNNPNQVYINISAIPDTEDQFLLCYYSNN----LHSVVGISQPFKIP------IRSFLREDTLYEPEPQI------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BT40-1", "uniprot_id": "INP5K_HUMAN", "id": "Q9BT40-1", "name": "Inositol polyphosphate 5-phosphatase K", "aln": "--------------------------MSSRKLSG---------------------------------------------PKGRRLSIHVVTWNVASAAPP-LDLSDLLQLN----------NRNLNLDIYVIGLQELNSGIISLLSDAAFNDSWSSFLMDVLSPLSFIKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICLKLYGYYVSIINCHLPPHISNNYQRLEHFDRILEMQNCEGRDIPNILDHDLIIWFGDMNFRIEDFG-LHFVRESIKN-RCYGGLWEKDQLSIAKKH-DPLLREFQEGRLLFPPTYKFDRNSNDYDT---------SEKKRKPAWTDRILWRLKRQP-CAGPDTPIPPASH----------FSLSLRGYSSHMTYGISDHKPVSGTFDLELKPLVSAPLIVLMPEDLWTVENDMMVSYSSTSDFPSSPWDWIGLYKVGLRDVNDYVSYAWVGDS-------------------------------------KVSCSDNLNQVYIDISNIPTTEDEFLLCYYSNS----LRSVVGISRPFQIP------PGS-LREDPLGEAQPQI------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AHJ9-1", "uniprot_id": "A0A8M3AHJ9_DANRE", "id": "A0A8M3AHJ9-1", "name": "", "aln": "MSSSMEEISEYFSEKLQRQRSDSAASSSTQSTSSRQHVRQRLAMLLTCVDDLDTDHKLQTQVAKTLDEAFLVCRQIAGRPKKNPFRLYVVTWNVATAEPP-DDVNALLQLN----------SPKK-PDLYVIGLQEVRAAPLKFVSDLAFEDSWSHLFMDTLSPLHYIKVSSIRMQGLLLLFFSKLEHVPFIRDIQVTYTRTGLYGYWGNKGGVTIRLSFYGHMLCFLNCHLTAHMNYASQRVDEFEHILDAQNFNTKNTPHVLDHKVVFWFGDLNFRIEDHG-MLFVRNCITS-QRFNLLWPKDQLTMMKQK-EVILQKFEEGPLDFQPTYKFDLNSDNYDTRVQTTWFGFNGKKRKPAWCDRILWRVKPKASLTENTNEEEPEKQQEEEREDEFPLKMTQEYYTSKMEYGISDHKPVIGIFRLELRKMYETPLVQVFAEGEWSADFDAVITYRLLQAFASSAWDWIGLYKVGFKSVSDYITYAWVKDD-------------------------------------QVSFNEELFQVYMNKDEIPVLGGECVLCYYSSN----LQCIVGISQPFKVQE-----SRAAIEEGLVPENINGLNQALAS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9PHS8-1", "uniprot_id": "M9PHS8_DROME", "id": "M9PHS8-1", "name": "Inositol polyphosphate-related phosphatase domain-containing protein", "aln": "----MSQTEASKTPKIPDSEPDGSKGKGKQ--------------------------------------------------QLETYRVYVVTWNVGSRFPDNISLRHLLGLQDVTVDKDTKETNAHLPDIYALGLQEVNAQPQQQVLGLFKEDPWTHKAKELLRNYDYVAVKTEQMQGLLLSMFVRRQHVEHLQDIEAEFTRTGFGGIWGNKGAVSVRFTLYGCGLAFVVAHLTAHDHMMDERIEDYKQILENHHYHVKRYREIYDHDYVFWFGDLNFRLQGSDSSTEVRELVRDESQHEALIQRDQLYQVREKSQLAFQVLQERLPAFPPTFKFREGTSEYDL------------KRRPAWTDRIMYAVQPLNRQPGMQLS------------------IEQCSYKSHPLYTISDHKPVTSDFTIKLYPNVRAPGVVFSPLSLWKIGDENTVEYHKQAEFDEGSNDWIGIFPSEYASLADYVAYEYVNQAESPSSSDSNHQPDPFETPSHHRRGRHHHRNRQRQRRHQEANAQELVRLDFADDVELRHGEQYLLIYFRSTGVRGVTSLAGVSGVFVAEKRHGSPHRTEYHVDXLAEALDIFIL----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : ::******.: * .: ** *: . *:* :****:. . : . :*.*: : * : :. :***:** .* : :*: .:: :.. **: * *****.:.: :.:** :.:: .**..* :*::.:.:**: . .: **. ::****:***::. . *:: : . * :*** ::: : :: ::* * **:** :.:** **:*** ***:: :: . : * *: * ******* . * ::* .* : . . *. : : * * ... ****:: : **::* :* : : : :: :: : . : :* *: .. : .:.*:* * . . : * : ", "identical_positions": 102, "similar_positions": 138, "identity": "16.8%" }, { "cls_id": "homologset.agr.MGI:1194908", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O54910-1", "uniprot_id": "IKBE_MOUSE", "id": "O54910-1", "name": "NF-kappa-B inhibitor epsilon", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------MSDARKGPDEADDSQCDSGIESLRSLRSLPEPTAAPGSGSSQSGCPQPWRHAPET--------HKEPE-KEDADGERADSTYASSSLTESFPLLERPEAKDPSPPAPGSPLPPAGVLSPQQLEALTYISEDGDTLLHLAVIHEAPSVLFCCLAFLPQ-EVLDIQNNLYQTALHLAVHLDQPDVVRALVLKGASRILQDQHGDTALHVACRRQNLACACCLLEEQ-----PEPGRQLSH---------------PLDLQLKNWQGLACLHIATLQRNQPLIELLLQNGADIDVQEGTSGKTALHLAVETQERSLVQFLLQAGARVDARMLN--GCTPLHLAAGRGLNSISSTLCEAGADSLLLNVEDETPQDLA--EDLLSYLPFDD----LKISGKPLLCTD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6P780-1", "uniprot_id": "Q6P780_RAT", "id": "Q6P780-1", "name": "NF-kappa-B inhibitor epsilon", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------MSDARKGPDEADDSQCDSGIESLRSLRSLPDPAAAPVSGSSHSGCPQPWSHAPKT--------DKEPEGKEDADGERADSTYASSSLTESLPLLERPEAKDPNPPTPSSPVSPAGVLSPQQLEALTYISEDGDTLLHLAVIHEAPSVLFCCLAFLPQ-EVLDIQNNLYQTALHLAVHLDQPDVVRALVLKGASRILQDQHGDTALHVACQRQNLACACCLLEEQ-----PEPGRQPSH---------------PLDLQLKNWQGLACLHIATLQRNQPLIELLLQNGADIDAQEGTSGKTALHLAVETQERSLVQFLLQAGARVDARMLN--GCTPLHLAAGRGLNSISSTLCEAGADSLLLNVEDETPQDLA--EDLLSYLPFDD----LKISGKPLLCTD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O00221-1", "uniprot_id": "IKBE_HUMAN", "id": "O00221-1", "name": "NF-kappa-B inhibitor epsilon", "aln": "MNQRRSESRPGNHRLQAYAEPGKGDSGGAGPLSGSARRGRGGGGAIRVRRPCWSGGAGRGGGPAWAVRLPTVTAGWTWPALRTLSSLRAGPSEPHSPGRRPPRAGRPLCQADPQPGKAARRSLEPDPAQTGPRPARAAGMSEARKGPDEAEESQYDSGIESLRSLRSLPESTSAPASGPSD-GSPQPCTHPPGP--------VKEPQEKEDADGERADSTYGSSSLTYTLSLLGGPEAEDP---APRLPLPHVGALSPQQLEALTYISEDGDTLVHLAVIHEAPAVLLCCLALLPQ-EVLDIQNNLYQTALHLAVHLDQPGAVRALVLKGASRALQDRHGDTALHVACQRQHLACARCLLEGR-----PEPGRGTSH---------------SLDLQLQNWQGLACLHIATLQKNQPLMELLLRNGADIDVQEGTSGKTALHLAVETQERGLVQFLLQAGAQVDARMLN--GCTPLHLAAGRGLMGISSTLCKAGADSLLRNVEDETPQDLT--EESLVLLPFDD----LKISGKLLLCTD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q03017-1", "uniprot_id": "CACT_DROME", "id": "Q03017-1", "name": "NF-kappa-B inhibitor cactus", "aln": "-------------------MPSPTKAAEAATKATATSDCSCSAASVEQRAPSNAANPSSSLATSGKIGG--------------KTQDQTAAINKQKEFAVPNETSDSGFISGPQSSQIFSEEIVPDSEE--------QDKDQQESAPQKEQPVVLDSGIIDEEEDQEEQEKEEEHQDTTTATADSMRLKHSADTGIPQWTVESHLVSRGEQLNNLGQSSSTQITGRSKVQSSTASTANANPSGSGATSSAPPSSINIMNAWEQFYQQNDDGDTPLHLACISGSVDVVAALIRMAPHPCLLNIQNDVAQTPLHLAALTAQPNIMRILLLAGAEPTVRDRHGNTALHLSCIAGEKQCVRALTEKFGATEIHEAHRQYGHRSNDKAVSSLSYACLPADLEIRNYDGERCVHLAAEAGHIDILRILVSHGADINAREGKSGRTPLHIAIEGCNEDLANFLLDECEKLNLETATYAGLTAYQFACIMNKSRMQNILEKRGAETVTPPDSDYDSSDIEDLDDTKMYDRFGDPRYFVSYNGGNPMTVA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: ...*:: : **** . .. :. : . .: . . *.. . : . *: :. .*: :. : . . :* . . . . : * : .:**** :*** * : *: . : : *: :*:***:: **.****. **. :* *:* **. ::*:**:****::* . *. .* * *. * .* . **:::*::* *:*:*: : ::.:*: :****:.:**.**:*.**:*:* :..*.:***: ::: . . * *. ::*. . :.. * : **::: .* ..*: :: *.* :. .* : . ", "identical_positions": 87, "similar_positions": 130, "identity": "16.08%" }, { "cls_id": "homologset.agr.MGI:1194909", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XFW9-1", "uniprot_id": "Q5XFW9_RAT", "id": "Q5XFW9-1", "name": "Radial spoke head 1 homolog", "aln": "-------MSDLGSEELEEEGENDLGEYEGERNELGERHGHGKARLPNGDTYEGNYESGKRHGQGTYKFKNGARYVGDYVKNKKHGQGTFVYPDGSRYEGEWADDQRHGHGVYYYVNNDTYTGEWFNHQRHGQGTYFYAETG------SKYVGTWVHGQQEGAAELIHLNHR----YQGKFINKNPVGPGKYVFD-----VGCEQHGEYRLTDVE-RGEEEEEEETLVSIVPKWKALK-----ITELALWTPTLSEEHPPAEGQGQEEVQGATGAGEPSDDIQA--EGFEVDAEPRTGEE-DID-FRQESQENS-----YDLDQGNPNFDEE---QLDLQE----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VIG3-1", "uniprot_id": "RSPH1_MOUSE", "id": "Q8VIG3-1", "name": "Radial spoke head 1 homolog", "aln": "-------MSDLGSEELEEEGENDLGEYEGERNEVGERHGHGKARLPNGDTYEGSYEFGKRHGQGTYKFKNGARYTGDYVKNKKHGQGTFIYPDGSRYEGEWADDQRHGQGVYYYVNNDTYTGEWFNHQRHGQGTYLYAETG------SKYVGTWVHGQQEGAAELIHLNHR----YQGKFMNKNPVGPGKYVFD-----IGCEQHGEYRLTDTE-RGEEEEEEETLVNIVPKWKALN-----ITELALWTPTLSEEQPPPEGQGQEEPQGLTGVGDPSEDIQA--EGFEGELEPRGADE-DVDTFRQESQENS-----YDIDQGNLNFDEE---PSDLQD----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WYR4-1", "uniprot_id": "RSPH1_HUMAN", "id": "Q8WYR4-1", "name": "Radial spoke head 1 homolog", "aln": "-------MSDLGSEELEEEGENDIGEYEGGRNEAGERHGRGRARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKKHGQGTFIYPDGSRYEGEWANDLRHGHGVYYYINNDTYTGEWFAHQRHGQGTYLYAETG------SKYVGTWVNGQQEGTAELIHLNHR----YQGKFLNKNPVGPGKYVFD-----VGCEQHGEYRLTDME-RGEEEEEEE-LVTVVPKWKATQ-----ITELALWTPTLPKKPTSTDGPGQDAP-GAESAGEPGEEAQALLEGFEGEMDMRPGDE-DADVLREESREYDQEEFRYDMDEGNINSEEEETRQSDLQD----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B7A0-1", "uniprot_id": "A0ACD6B7A0_DANRE", "id": "A0ACD6B7A0-1", "name": "Radial spoke head 1 homolog", "aln": "-------MSDVGSEEFDEE-RSSLGEYEGDRNEAGERHGQGKAVLPNGDTYQGAYENGKRSGQGTYKFKNGARYTGEWYMNLKHGEGTFYYPDGSKYEGMWVDDQRQGLGVYTYPNGDTYDGEWLHHQRHGQGAYTYHDTG------SQYVGTWIMGKMESAGELIYLNHR----YQGNFINNNPSGPGKYVFD-----IGCEQHGEYLQIEQV-KGDAEEEEPAMTTIL-KWKPKA-----ITALSVWTTERDSGHTAVEE----------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VK29-1", "uniprot_id": "Q9VK29_DROME", "id": "Q9VK29-1", "name": "", "aln": "MAMTEMSEEDLSAPEEEEDLGPNIGLYIGGRNAAGQRQGRGWAILPNGDQYDGNYRKGRRHGIGVYVFKDGSRYYGQYRCGKRCGRGIFIYPDGSVYEGNWRKNLKHGKGRYKYVNGDNYSGDWFKGQRHGVGIYHFNSGKDGCCLSVRMKATWNSNMRTGPFELYIGNEDKCTILHGIWDNLYPSGPAVFSFNNRYLLLGYFLPASYNMKAISNEDEMEDAEERLEDEMGEAEPMEPTLWFAQEMAVYDFSLLPQEPVPLAISDSELSVCSLSTEPSMRSEEKISWYGEGEEAEGEEGGEMECFPCECDLTDVSEVETESEVCKIDANPCCIEILKQPECPDP", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .*:.: * :*: .:* * * ** *:*:*:* * ***** *:* *. *:* * * * **:*:** *:: . : *.* * ***** *** * .: ::* * * * *.*.* *:*: **** * * : . : .** . .. ** *. :* : * * **. : *: :* ..* ..: *: * : : : :. :::: . ", "identical_positions": 74, "similar_positions": 59, "identity": "21.51%" }, { "cls_id": "homologset.agr.MGI:1194910", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q71UF4-1", "uniprot_id": "RBBP7_RAT", "id": "Q71UF4-1", "name": "Histone-binding protein RBBP7", "aln": "MASK-----EMFEDTVEERVINEEYKIWKKNTPFLYDLVMTHALQWPSLTVQWLPEVTKPEGKDYALHWLVLGTHTS-DEQNHLVVARVHIPNDDAQFDASHCDSDKG-EFGG-FGSVTGKIECEIKINHEGEVNRARYMPQNPHIIATKTPSSDVLVFDYTKHPAKPDPSGECNPDLRLRGHQKEGYGLSWNSNLSGHLLSASDDHTVCLWDINAGPKEGKIVDAKAIFTGHSAVVEDVAWHLLHESLFGSVADDQKLMIWDTRSNTTSKPSHLVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHTFESHKDEIFQVHWSPHNETILASSGTDRRLNVWDLSKIGEEQSAEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQIWQMAENIYNDEESDVTTSELEGQGS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q16576-1", "uniprot_id": "RBBP7_HUMAN", "id": "Q16576-1", "name": "Histone-binding protein RBBP7", "aln": "MASK-----EMFEDTVEERVINEEYKIWKKNTPFLYDLVMTHALQWPSLTVQWLPEVTKPEGKDYALHWLVLGTHTS-DEQNHLVVARVHIPNDDAQFDASHCDSDKG-EFGG-FGSVTGKIECEIKINHEGEVNRARYMPQNPHIIATKTPSSDVLVFDYTKHPAKPDPSGECNPDLRLRGHQKEGYGLSWNSNLSGHLLSASDDHTVCLWDINAGPKEGKIVDAKAIFTGHSAVVEDVAWHLLHESLFGSVADDQKLMIWDTRSNTTSKPSHLVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHTFESHKDEIFQVHWSPHNETILASSGTDRRLNVWDLSKIGEEQSAEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQIWQMAENIYNDEESDVTTSELEGQGS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q60973-1", "uniprot_id": "RBBP7_MOUSE", "id": "Q60973-1", "name": "Histone-binding protein RBBP7", "aln": "MASK-----EMFEDTVEERVINEEYKIWKKNTPFLYDLVMTHALQWPSLTVQWLPEVTKPEGKDYALHWLVLGTHTS-DEQNHLVVARVHIPNDDAQFDASHCDSDKG-EFGG-FGSVTGKIECEIKINHEGEVNRARYMPQNPHIIATKTPSSDVLVFDYTKHPAKPDPSGECNPDLRLRGHQKEGYGLSWNSNLSGHLLSASDDHTVCLWDINAGPKEGKIVDAKAIFTGHSAVVEDVAWHLLHESLFGSVADDQKLMIWDTRSNTTSKPSHLVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHTFESHKDEIFQVHWSPHNETILASSGTDRRLNVWDLSKIGEEQSAEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQIWQMAENIYNDEESDVTASELEGQGS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7ZTY4-1", "uniprot_id": "RBBP7_DANRE", "id": "Q7ZTY4-1", "name": "Histone-binding protein RBBP7", "aln": "MADK-----EVYDDAVEERVINEEYKIWKKNTPFLYDLVMTHALEWPSLTVQWLPDVNRPEGKDYVVHRLVLGTHTS-DEQNHLVIASAQIPNDDAQFDASHYDSEKGAEFGG-FGSVSGKIEIEIKINHEGEVNRARYMPQNPCIIATKTPTSDVLAFDYTKHPSKPDPSGDCSPDLRLRGHQKEGYGLSWNPNLSGNLLSASDDHTICLWDISGAPKEGKIVDAKTIFTGHTAVVEDVSWHLLHESLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSAEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENIYNDEEPDTPASELEGQAS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24572-1", "uniprot_id": "CAF1_DROME", "id": "Q24572-1", "name": "Chromatin assembly factor 1 p55 subunit", "aln": "MVDRSDNAAESFDDAVEERVINEEYKIWKKNTPFLYDLVMTHALEWPSLTAQWLPDVTKQDGKDYSVHRLILGTHTS-DEQNHLLIASVQLPSEDAQFDGSHYDNEKG-EFGG-FGSVCGKIEIEIKINHEGEVNRARYMPQNACVIATKTPSSDVLVFDYTKHPSKPEPSGECQPDLRLRGHQKEGYGLSWNPNLNGYLLSASDDHTICLWDINATPKEHRVIDAKNIFTGHTAVVEDVAWHLLHESLFGSVADDQKLMIWDTRNNNTSKPSHTVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLHVWDLSKIGEEQSTEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWIICSVSEDNIMQVWQMAENVYNDEEPEIPASELETNTA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39984-1", "uniprot_id": "HAT2_YEAST", "id": "P39984-1", "name": "Histone acetyltransferase type B subunit 2", "aln": "-----------MENQEKPLSVDEEYDLWKSNVPLMYDFVSETRLTWPSLTVQWLPTPVQELDGGFIKQELIIGTHTSGEEENYLKFAEINLPKEILSNEDPQ--EEAGEEYQSSLPAPRSNIRITAKYEHEEEITRARYMPQDPNIVATINGQGTVFLYSRSEGLQS-----------TLKFHKDNGYALSFSTLVKGRLLSGSDDHTVALWEVGSGGDPTKPVRTWNDL--HSDIINDNKWHNFNKDLFGTVSEDSLLKINDVRANNTTIDTVKCPQP---FNTLAFSHHSSNLLAAAGMDSYVYLYDLRNMKEPLHHMSGHEDAVNNLEFSTHVDGVVVSSGSDNRLMMWDLKQIGAEQTPDDAEDGVPELIMVHAGHRSSVNDFDLNPQIPWLVASAEEENILQVWKCSHSLPIVGGPPKVNKDIIS---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : ::***.:**.*.*::**:* * *****.**** : . .: : *::***** :*:*:* .* ::*.: . : .: .: * *: . : : .:*. * :** *:.*******:. ::** . . *: :. :: . *: *:.:**.**:.. :.* ***.*****:.**::.. . : : : : *: :::* ** :::.***:*::*. * * *.* *.*: : .* *:*. :*. :**:.. *. * *:****:* ** :..*:* : ::.:*.* : ::.***:*.** :***.:** **:.:***** ***:::*.** :.:.**. **: **::.*..*:**:*:*: :..: . .:: ", "identical_positions": 136, "similar_positions": 155, "identity": "31.41%" }, { "cls_id": "homologset.agr.MGI:1194912", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q60972-1", "uniprot_id": "RBBP4_MOUSE", "id": "Q60972-1", "name": "Histone-binding protein RBBP4", "aln": "MADK----EAAFDDAVEERVINEEYKIWKKNTPFLYDLVMTHALEWPSLTAQWLPDVTRPEGKDFSIHRLVLGTHTS-DEQNHLVIASVQLPNDDAQFDASHYDSEKGEFGGFGSVSGKIEIEIKINHEGEVNRARYMPQNPCIIATKTPSSDVLVFDYTKHPSKPDPSGECNPDLRLRGHQKEGYGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLHESLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENIYNDEDPEGSVDPE-GQGS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q09028-1", "uniprot_id": "RBBP4_HUMAN", "id": "Q09028-1", "name": "Histone-binding protein RBBP4", "aln": "MADK----EAAFDDAVEERVINEEYKIWKKNTPFLYDLVMTHALEWPSLTAQWLPDVTRPEGKDFSIHRLVLGTHTS-DEQNHLVIASVQLPNDDAQFDASHYDSEKGEFGGFGSVSGKIEIEIKINHEGEVNRARYMPQNPCIIATKTPSSDVLVFDYTKHPSKPDPSGECNPDLRLRGHQKEGYGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLHESLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENIYNDEDPEGSVDPE-GQGS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6P3H7-1", "uniprot_id": "RBBP4_DANRE", "id": "Q6P3H7-1", "name": "Histone-binding protein RBBP4", "aln": "MADK----EAAFDDAVEERVINEEYKIWKKNTPFLYDLVMTHALEWPSLTAQWLPDVTRPEGKDFSVHRLVLGTHTS-DEQNHLVIASVQLPNDDAQFDASHYDSEKGEFGGFGSVSGKIEIEIKINHEGEVNRARYMPQNPCIIATKTPTSDVLVFDYTKHPSKPDPSGECTPDLRLRGHQKEGYGLSWNPNLRSCLLSASDDHTICLWDISTVPKEGKIVDAKTIFTGHTAVVEDVSWHLLHESLFGSVADDQKLMIWDTRSNNTSKPSHAVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENIYNDEDPEGAADTE-VQG--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24572-1", "uniprot_id": "CAF1_DROME", "id": "Q24572-1", "name": "Chromatin assembly factor 1 p55 subunit", "aln": "MVDRSDNAAESFDDAVEERVINEEYKIWKKNTPFLYDLVMTHALEWPSLTAQWLPDVTKQDGKDYSVHRLILGTHTS-DEQNHLLIASVQLPSEDAQFDGSHYDNEKGEFGGFGSVCGKIEIEIKINHEGEVNRARYMPQNACVIATKTPSSDVLVFDYTKHPSKPEPSGECQPDLRLRGHQKEGYGLSWNPNLNGYLLSASDDHTICLWDINATPKEHRVIDAKNIFTGHTAVVEDVAWHLLHESLFGSVADDQKLMIWDTRNNNTSKPSHTVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLHVWDLSKIGEEQSTEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWIICSVSEDNIMQVWQMAENVYNDEEPEIPASEL-ETNTA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q71UF4-1", "uniprot_id": "RBBP7_RAT", "id": "Q71UF4-1", "name": "Histone-binding protein RBBP7", "aln": "MASK-----EMFEDTVEERVINEEYKIWKKNTPFLYDLVMTHALQWPSLTVQWLPEVTKPEGKDYALHWLVLGTHTS-DEQNHLVVARVHIPNDDAQFDASHCDSDKGEFGGFGSVTGKIECEIKINHEGEVNRARYMPQNPHIIATKTPSSDVLVFDYTKHPAKPDPSGECNPDLRLRGHQKEGYGLSWNSNLSGHLLSASDDHTVCLWDINAGPKEGKIVDAKAIFTGHSAVVEDVAWHLLHESLFGSVADDQKLMIWDTRSNTTSKPSHLVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHTFESHKDEIFQVHWSPHNETILASSGTDRRLNVWDLSKIGEEQSAEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQIWQMAENIYNDEESDVTTSELEGQGS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P39984-1", "uniprot_id": "HAT2_YEAST", "id": "P39984-1", "name": "Histone acetyltransferase type B subunit 2", "aln": "-----------MENQEKPLSVDEEYDLWKSNVPLMYDFVSETRLTWPSLTVQWLPTPVQELDGGFIKQELIIGTHTSGEEENYLKFAEINLPKEILSNEDPQEEAGEEYQSSLPAPRSNIRITAKYEHEEEITRARYMPQDPNIVATINGQGTVFLYSRSEGLQS-----------TLKFHKDNGYALSFSTLVKGRLLSGSDDHTVALWEVGSGGDPTKPV--RTWNDLHSDIINDNKWHNFNKDLFGTVSEDSLLKINDVRANNTTIDTVKCPQP---FNTLAFSHHSSNLLAAAGMDSYVYLYDLRNMKEPLHHMSGHEDAVNNLEFSTHVDGVVVSSGSDNRLMMWDLKQIGAEQTPDDAEDGVPELIMVHAGHRSSVNDFDLNPQIPWLVASAEEENILQVWKCSHSLPIVGGPPKVNKDIIS----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::: : ::***.:**.*.*::**:* * *****.**** .: . .: : *::***** :*:*:* .* :::*.: . : .: : : ..: : .:*. * :** *:.*******:. ::** . . *:::. :: . *: *:.:**.**:.. : . ***.*****:.**::.: . : : : *: :::* ** :::.***:*::*. * * *.* *.*: : .* *:*. :*. :**:.. *. * *:****:* ** :..*:* : ::.:*.* : ::.***:*.** :***.:** **:.:***** ***:::*.** :.:.**. **: **::.*..*:**:*:*: :..: . . ", "identical_positions": 133, "similar_positions": 156, "identity": "30.79%" }, { "cls_id": "homologset.agr.MGI:1194915", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P55926-1", "uniprot_id": "ASIC1_RAT", "id": "P55926-1", "name": "Acid-sensing ion channel 1", "aln": "--------------MELKTEEEE----------------------------VGGVQP-------------VSIQAFASSSTLHGLAHIFSYER-LSLKR-ALWALCFLGSLAVLLCVCTERVQYYFCYH-HVTKLD--EVAASQLTFPAVTLCN---LNEFRFSQVSK-----------------NDLYHAGELLALLNNRYEIPDTQMADEKQLEILQDKANFRSFKPKPFNMREFYDRAGHDIRDMLLSCHFR-GEACSA-EDFKVVFTRYGKCYTFNS-----------------------------------GQDGR------PRLKTMKGGTGNGLEIMLDIQQDEYLPVWGETDETSFEAGIKVQIHSQDEPPFIDQLGFGVAPGFQTFVSCQEQRLIYLPSPWGTCNAVT-----MDS--DFFDS-----YSITACRIDCETRYLVENCNCR-MVHMPGDAPYC----TPEQYKECADPA--------------LDFLVEKDQEYCVCEMPCNLTRYGKELSMV-----KIPSKASAK-YLAKKF-----NKSEQY--------------IGENILVLDIFFEVLNYETIEQKKAYEIAGLLGDIGGQMGLFIGASILTVLELFDYAYEVIKHRLCRRGKCQKEAKRSSADKGVALSLDDVKRHNPCESLR------------------GHPAGMTYAANILPHHPARGTFEDFTC-------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6NXK8-1", "uniprot_id": "ASIC1_MOUSE", "id": "Q6NXK8-1", "name": "Acid-sensing ion channel 1", "aln": "--------------MELKTEEEE----------------------------VGGVQP-------------VSIQAFASSSTLHGLAHIFSYER-LSLKR-ALWALCFLGSLAVLLCVCTERVQYYFCYH-HVTKLD--EVAASQLTFPAVTLCN---LNEFRFSQVSK-----------------NDLYHAGELLALLNNRYEIPDTQMADEKQLEILQDKANFRSFKPKPFNMREFYDRAGHDIRDMLLSCHFR-GEACSA-EDFKVVFTRYGKCYTFNS-----------------------------------GQDGR------PRLKTMKGGTGNGLEIMLDIQQDEYLPVWGETDETSFEAGIKVQIHSQDEPPFIDQLGFGVAPGFQTFVSCQEQRLIYLPSPWGTCNAVT-----MDS--DFFDS-----YSITACRIDCETRYLVENCNCR-MVHMPGDAPYC----TPEQYKECADPA--------------LDFLVEKDQEYCVCEMPCNLTRYGKELSMV-----KIPSKASAK-YLAKKF-----NKSEQY--------------IGENILVLDIFFEVLNYETIEQKKAYEIAGLLGDIGGQMGLFIGASILTVLELFDYAYEVIKHRLCRRGKCQKEAKRNSADKGVALSLDDVKRHNPCESLR------------------GHPAGMTYAANILPHHPARGTFEDFTC-------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P78348-2", "uniprot_id": "ASIC1_HUMAN", "id": "P78348-2", "name": "Acid-sensing ion channel 1", "aln": "--------------MELKAEEEE----------------------------VGGVQP-------------VSIQAFASSSTLHGLAHIFSYER-LSLKR-ALWALCFLGSLAVLLCVCTERVQYYFHYH-HVTKLD--EVAASQLTFPAVTLCN---LNEFRFSQVSK-----------------NDLYHAGELLALLNNRYEIPDTQMADEKQLEILQDKANFRSFKPKPFNMREFYDRAGHDIRDMLLSCHFR-GEVCSA-EDFKVVFTRYGKCYTFNS-----------------------------------GRDGR------PRLKTMKGGTGNGLEIMLDIQQDEYLPVWGETDETSFEAGIKVQIHSQDEPPFIDQLGFGVAPGFQTFVACQEQRLIYLPPPWGTCKAVT-----MDSDLDFFDS-----YSITACRIDCETRYLVENCNCR-MVHMPGDAPYC----TPEQYKECADPA--------------LDFLVEKDQEYCVCEMPCNLTRYGKELSMV-----KIPSKASAK-YLAKKF-----NKSEQY--------------IGENILVLDIFFEVLNYETIEQKKAYEIAGLLGDIGGQMGLFIGASILTVLELFDYAYEVIKHKLCRRGKCQKEAKRSSADKGVALSLDDVKRHNPCESLR------------------GHPAGMTYAANILPHHPARGTFEDFTC-------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q708S7-1", "uniprot_id": "ASI1A_DANRE", "id": "Q708S7-1", "name": "Acid-sensing ion channel 1A", "aln": "---------MKTSVMDLKVEPMD----------------------------IDFDQP-------------PPLQVFAHTSTLHGISHIFSYEK-ITAKC-CLWVVFFLSSLTFLMYVCIDRIQFYLEYP-HVTKLD--EITTPVMVFPAVTICN---LNSIRFSRITR-----------------NDLYHAGELLALLNSRHEVREAHLVEESVMEVLKSKTDFRSFKPRHFNMWEFYNRTGHDIKDMLLSCQFR-GSPCRP-EDFSVVFTRYGKCYTFNS-----------------------------------GETGP------PRVS-VKGGMGNGLEIMLDIQQDEYLPVWGESDESSFEAGIKVQIHSQDEPPFIDQLGFGVAPGFQTFVSCQEQRLVYLPAPWGSCKSTP-----PSS--DYFRA-----YSISACRTDCETRYLVENCNCR-MVHMPGDAPYC----TPVLYKECAHPA--------------LDFLVETDSDYCSCETPCNITRYSKELSFV-----KIPSKASVK-YLAKKY-----SKSEKY--------------ITENVMVLDVFFEALNYETIEQRKAYEVAGLLGDIGGQMGLFIGASILTILELFDYLYEVMKYRLCRCSNKKHHNNNNNTDHNAVFSLDDVN----CHVSK------------------FH--------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q708S6-1", "uniprot_id": "ASI1C_DANRE", "id": "Q708S6-1", "name": "Acid-sensing ion channel 1C", "aln": "-------------MTAMKGDSEDS---------------------------IESMRP-------------SNLQVFANNSTLHGMSHIFAYGH-MTFRR-FLWTLSFMGSLGLLMYVCMDRVYYYFEFP-HVTKLD--EVAAPNLTFPAVTFCN---LNEFRFSKITK-----------------NDLYHVGELLALLNENYQIANPHLADPEVLTLLKEKASFNGFKPKQFNMTDFYNRTGHDINEMLLQCSFR-GEECFP-LNFTTIYTRYGKCYTFNS-----------------------------------GLDGN------PLLTTLKGGTGNGLEIMLDIQQDEYLPVWGDTDETSYEAGIKVQIHSQDEPPFIDQLGFGVAPGFQTFVSCQQQLLLYLPPPWGDCRSAP-----MDS--EYFST-----YSITACRIDCETRYLLENCNCR-MVHMPGTSTVC----TPEQYKDCADPA--------------LDFLVEKDNDYCVCDTPCNMTRYGKELSMV-----KIPSKASAK-YLAKKF-----NKTEQY--------------ITDNILVLDIFFEALNYEKIEQKKAYEVAGLLGDIGGQMGLFIGASVLTILEIFDYLYEVLKDKILGSVLRKRRPHRSASDNLVIVSLHDFK----ISSVF------------------LLASYMCFVCYIVLLNAACVYLPFVVGSNSGK--------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q708S8-1", "uniprot_id": "ASI1B_DANRE", "id": "Q708S8-1", "name": "Acid-sensing ion channel 1B", "aln": "-------MVRITCTISFSTDDEPVGRSRQGSFDDHYKRVVWSKDGEQGKYQEEGDDPDAYDGPEDEEAPDISLATFFGGCSLHGANHVFVEDKKFSIRQ-GLWALVFLLAISMFLLQVVDRVIYYLQYD-YVTLLD--ERNAKNMTFPAITLCN---YNTFRRSQLSY-----------------SDLLFMGPLLGYEDN--------MAPGIPLAPEPDRQGSR------FSLAEFFNRTRHRMDDMLLECNFA-GKECGA-EHWREIFTRYGKCYTFNS-----------------------------------GQDGR------PLLITTKGGMGNGLEIMLDIQQDEYLPVWGETDETTFEAGIKVQIHTQDEPPFIDQLGFGVAPGFQTFVSCQEQRLTYLPPPWGDCKATP-----IDS--DFFNT-----YSITACRIDCETRYLVENCNCR-MVHMPGDAPYC----TPEQYKECADPA--------------LDFLVERDNDYCVCETPCNMTRYGKELSFV-----RIPSKASAK-YLAKKY-----NKTEQY--------------ISDNIMVLDIFFEALNYETIEQKKAYELAGLLGDIGGQMGLFIGASILTILELFDYLYEVIKFKLCRCAKKKHQ-RSNNNERGAVLSLDDVKRHAPCDNLR------------------TPST---YPANMLPHHPGQGNFEDFTC-------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7KTW2-1", "uniprot_id": "Q7KTW2_DROME", "id": "Q7KTW2-1", "name": "", "aln": "---------------------------------------------------MEMLKY-----------VIS------------------DNNYSWWIK--LYFAIIFALVLFVAVNLAVGIYNKWDSTP-VIIGISSKMTPIDQIPFPTITVCN---MNQAKKSKVEH-----------------LMPGSIRYAMLQKTCY--------KESNFSQYMDTQHRNETFSN-------FILDVSEKCADLIVSCIFH-QQRIPCTDIFRETFVDEGLCCIFNVLHPYYLYKFKSPY-IRDFTSSDRFADIAVDWDPISGYPQR-----LPSSYYPRPGVGVGTSMGLQIVLNGHVDDYFCS--STNGQGFKILLYNPIDQPRMKESGLPVMIGHQTSFRIIARNVEATPSIRNIHRTKRQCIFSDEQELLFYRY-----YTRRNCEAECDSMFFLRLCSCI-PYYLPLIYPNA----SVCDVFHFECLN--------------RAESQIFDLQSSQCKEFCLTSCHDLIFFPD-----AFSTPFSQK-DVKAQT-NYLTNFSSEY--------------MRKNLAVVNFFHTDNYFRSSVRTSYTGPTEYMASTGGIMSLMIGFSVIFLAEIIYIILFVSTLLLILIF------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W250-1", "uniprot_id": "Q9W250_DROME", "id": "Q9W250-1", "name": "", "aln": "-------------MEPSPSAGTERQGS-----------------------SLFLLKS-----------FVRSLRQFLNQTSLHGLKFVGDSGLSSWER--SFFLGSFVTALIITVHLISNIYVKWDSTP-VIIGISPQATSILKVPFPAITICN---MNQVQRSLVAN-----------------YREGSNESALLKLLCE--------SDSWESSEADEEFSASNFVTNNLKISEFVSNHSQSCERMLLFCRFS-AVERNCSQLFQQILTDEGLCCVFNFQPPEYLYKPFANN-NRNLTNSDGFES--VMWDPESGYPEQ-----LPPKFYPATASGTGITLGFTAVLDAEMGEYYCS--STNGPGFKVYFHNPIEVPKVKEAGLISAIGYETNYRIEMVRAEAVPAIRSISRDGRQCLFKNEKELIFYRI-----YTRLNCENECLAAFLYDTCSCI-PFDHPLIYSNA----SICSMGDTSCVR--------------RAQRASNRPGWAKCRQQCLPSCFDLNYLAS-----GFSFPLASN-NFQLAN-ALVESFNKSY--------------LSKNIAVINVYFRESVYYGNTKNAYVGLTEFLSNVGGVMGLFMGFSVISLAEILYFLILKPLAELFVWKRSSHVDSEKSLKHNAFG----IEKGQSSDNPS------------------FWHSKELYPKGVSISAYENAKSTKGLNYQ-----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q0KHW3-1", "uniprot_id": "Q0KHW3_DROME", "id": "Q0KHW3-1", "name": "", "aln": "MRVPRNRQRAFFASQQKRSRPQHLQIT-----------------------LSTWRRI-----------LSRNTDEFCRNTTIHGLKYINNSKLRSSDR--LFFGIALLVVLSLAIYLIQDAFDKWNTNP-VIVGIDPELTSIANEPFPAVTICN---LNQALAERVEH-----------------FSNDSVEFAMLQLLCR--------RKVDVELVKTNDSRWEEFILN----------ISQPCNSMVIHCRFG-ADDYECARLFHPIVTDEGLCCVFNMLHPRFMYRKRVPYSHRNISLPEGFHA--VNWHAELGYRKRGFQPDGDNPLYPRRAQGTGESLGLSLTLDVQADAYYCS--SSSSIGFKIALHSPNESPNVRETGVLLAPGMETKLRIDPSKILTEKHLRNVDRRSRRCLFHNELKLRWFAH-----YTQRNCVAECLSGWLIRHCGCV-TFYMPRLNAND----TICPLHKRECVE--------------LIRFR-TIIAMESCLDECLPSCFDLSFSAI-----AYSTRISLD-GFRETPSNGGWNFTDAY--------------VERSVAVVNMYFKDPTFRANKQTEFIGFSDFLSGVGGLMGLFLGFSFLSIAECVYFALIRPCRTCSEIRQLN------QPRVHQMN----LKRSPTPGNIR------------------YISAADWFQAELAHQQPNNRQHFNPA--------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q86LG1-1", "uniprot_id": "PPK28_DROME", "id": "Q86LG1-1", "name": "Pickpocket protein 28", "aln": "MRTLTESRRRQSGSSGCKKDSESDDDE------------------------NTICSR---------AAIKRSVVYYLKNSTLHGLKYIAEESITIPER--IFFGLAFVLVVILSVFFISNVYVKWSASP-IIISTSAKQKLTSNMPFPAITICN---LNQALLSKVDR-----------------IGRTSTNFSLLMGLCD----------QGGDTTISYIGTWKYFKA-------ILVDVAQPCEKMLLYCSFG-SREEDCSWLFTSILTDDGLCCNFNALHPSYLIRNYSDDVRLETAHPN-TRYELIDWTPEKGYARN-----LPEFYFPRTSGGTGIRMGLTVVLNASIAEYYCT--KSMSVGFKVLVHNPAELPKVSNYGFVVTAGREARIPIEPVYEDALPTIRSIKKSVRRCLFSDENDLAYYRT-----YSRKNCELECEAKLLLRECSCV-LYYLPRIDPLA----RVCGPNDNQCTD--------------RVQTEIESSLTNLSCENCWPGCFELTYRAT-----LSTASIVSDPRFQAGENLPEYIFHGPYS-------------NASEISILHFYYMTNIFRSTTKSEMFGFTEFLSNTGGLLGLFMGFSIFSVIEIFFYITVRPYCASRTLRQRHKRRLEQLSWLTPIRMPVRRALRRNRGGLLRN------------PPPPAYSDLQKFRGKLDKPETCKRKLWRTLQVRPVVDRADEELPTYPYLD------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "O61365-1", "uniprot_id": "NACH_DROME", "id": "O61365-1", "name": "Sodium channel protein Nach", "aln": "----------MGHQEELKPEQVDLKVTP----------------------FVGYLRR--------------TWSDFCATSSIHGLKYTRDEDTNKIVH--LVWLLISVVMFICAVVMARTFYMDYRSSP-TRMNVESDNTPVNRLYFPPVTICPDVLFNMQKSEAFLN-----------------TLRLPKGAELRGILRKLHIFYGFMLDDERYSAEDIEQMEALLFLNNLTIPEFVEHLRWNCDEILYRCRFN-GEIMDCSKIFQLSKTFFGHCCSFNLRQKGWVNN-------------------------KLNNLESFKVFHLNSLNFTAQRAIGGLRYGLSVVVRYKDDNYDPL--QSYSYGVKLLIQEADAFPSAHSAAKFIAFNSETFAAVRPQETFCSSAVKALIIEERNCVFQNEFPMRYFSD-----YVYPNCELNCRVTNMVKFCGCH-TYFFDFNRTSD----RICTFRDIPCLV--------------DNFANIITRKKS-TQCYCPLTCEHIDYDVQ-----LTNFPLELNMPVADKFYSG----------------------LAKNDGVLHVFINSFSYRRLRRDLLSNMVTLVSNLGSAFSLFVGMSMLSVVEIIYYFSVILRKNYKLECETRSQMLHKKPKF-------------------------------------------AWPKANDTHSKEQKSVFIIHKS------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A8JV41-1", "uniprot_id": "A8JV41_DROME", "id": "A8JV41-1", "name": "", "aln": "--------MPQEKRHPPESRTQRFLET-----------------------LVIFRRS-----------LIYQTKEFFQNSTLHGVRYIAESGRPIGEKF-MWFCFTSIGAVTALVIIMS-LWEKFQTNP-TITGLDT-DFHNQNVVFPTTVVCPEAAFDHDKTYEKVY-----------------NTLANYDEAQAQMYTPFLRILTSLNFENVRDAKVLSQSIPQNLLDAHTIREWAFEGHIDCKNVFVSCKYR-DEDIPCCDHFEPIYTEHGFCYAFNS----------------------------------------------RFKSTPTEDVKTGAPHDLYETDKKWALFFIPN-----STSRIFIFSNEEYFGSDFNAQIDWSEPQLVEVRISKKNTYTTDDARQLSIGQRKCIFSDEVKLNYFPDA----YTFSSCMKQCRMNKAIKLCKCNPPFYKPIRELSC----VINIFTNLIAYI--------------LLLYLTPKANVPMCSIKDFDCLDEFKSNIT-----NIKDCLQCELSCSKTVFNIDKLIKMSD--------------RPESLGVLVEFLTWPIIR-YKREVLFGWVDLLVSFGGIASLFLGFSLLSGVEIIYYFTLRACCMVYKNRQELYEIEEKIRQEPPPKIDLKLSLKSHNPRIGDTPTSAVLKVKPAEESAGPNPLGGYQRKHEKDYSLNTKNYYKTPKVVPDYGYTSKTKNSWTTYDHSQYMP", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A8DYP1-1", "uniprot_id": "A8DYP1_DROME", "id": "A8DYP1-1", "name": "", "aln": "----------------------------------------------------MWRKS--------------------------VMNFRGFIRSFVENKG-LLWIFVIGISGWSTVSILVLLKTRYETDS-TTIGVST-AYSRWINTFPSIGICLT---KSRAFNEFKA-----------------MMREYFQEDFAFSFTRMIYEYAFLNPNNIFTKEPTKNTSYPYNFNILDIR--RKMFPTNCTECFKEIYFRGELVTDCEEIFKFHVTEMGYCFLANN--------------------------------------------------LLDYDSIEEMPLRYSSLDNNRSLRLYMR--SSVMYKYEMYVNSPEDLPFFNSLTYTIS-TDPTTYAFNVEEIHNHEGVIDEPISQRKCKFPSESSIEGFPY------SFSACMSIIRSEFEMKTCDCS--LFNPKDRNES----LYCGLQHADCLI--------------KEGFATRVKEYVGSSTVCLPSCVEQQISLV-----GVITENGTL--------------------------------YNNNTQITEIQIASPPTVRYERKVTQTKLDLIVGIGSVAGLFFGASLLNLLEIISYFIKKLKTMIFG--------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V9Y5-1", "uniprot_id": "Q9V9Y5_DROME", "id": "Q9V9Y5-1", "name": "", "aln": "--MPVEMESLDQKPFRLAVGRAAWWIPNPGRVARYPPIRTLAPNHLPGTSAEDTRKLS----------FAAALKDLLQNLSFHCYSKLVESGRRIQER--FFWFVFHITALTVLIAFLWGTYTKEQEAL-VTTMYHP-MYPIWKVEFPAISVCSLNRISQRAAWQYAHNLSGKDPKQ-------RNASHFYDQLKAFMYMYYDPSDLMDIDNALRFQSFLDRFDTAKEELFFNTRNRMSALTPNCSDMFVSCRIA-GRLFDCMDKFETTLTSHGFCCTFNYDG---------------------------------RYVNK--------RDFRQRYFGPDMGLVLTLKTDPSDNFYKIN-----------GHNGYPDPFSGGVAERVAETGFNTLLPVRAKIFETLPEARSMSPSVRKCLFENEMPWIFARH-----YTFSKCISACRAQSVVSLCECV-PFSLPHRYIDGSEKRIYCTLQHLACLKRYEFKWLNVITSRENVTGLEHELQDALYCPLCLASCTETRYSVRGAMTLGLPTPSQIKGPARSNPGPRANNSYGPASSSGSAKGPVHSSSAPAELAVVRIYFAETHIQYFRQIIKSAWYETFSTIGNICGIIAGFSLIGICELLFFLAKQLWQACRAELRAELAHIHVQIRN---------------------------------------------AQVAEPEAERPMKLFILP--------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VAJ7-1", "uniprot_id": "Q9VAJ7_DROME", "id": "Q9VAJ7-1", "name": "", "aln": "MLYPLELPRARRPLYRDYGGKSGLIQTQR--------------------DARKNSRLG-----KLWHFMLPYLKDYAAESSVHGIRYLADPKMRNYLNIRVIWLLILLTTSIGAIVVYVDLNELYQTVR-IQTTIKNTMLPIFRIPFPSIGLCPRNRLNWKILETEAVDHFLG-----------ANVSAAQKDLFVKFFTAAGDPHLSRLNEMSNFFGNKTLTDELHMLDHLDLREVYKFIQFRCQDLFHTCRWR-GNPVNCCEVIEYQFTEAGLCFVFNTEIS-----------------------------PASRQKAR------EDKYYPLRTPHYGEGSGLDLFLRLNRSFIRPG-----KRGINVMIKQPQQ---WSDVVRHVPHEAHTRISITPRFTVTDERTRTVTPEIRRCIFGDEVDNPHYKNFPDFEYWVGNCRSRCHQEHVLNLCKCSPSIFFPISDKDN---FTACKASDFKCLY---------------DNRFTFSIERHPEEDDFVKNPFKESMICD-----CFTSCSQLVFDRVFTTTTLDNNETD----------------TEAGTMRLDIFYQSGWFIQYQTNMRFTFVELLASFGGIIGLFLGASLLSAFELAYYFSIGLYLYIHGKRKLRKP-----------------------------------------------------EPGVLTIQFGQRKITPIKF-------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8MLR6-1", "uniprot_id": "Q8MLR6_DROME", "id": "Q8MLR6-1", "name": "", "aln": "MSNERVLLWIRGAAARILRGLLALLWLILAG------------------CGRLFGRLR------------DVVAQAGAETGLLALSLCVNRSIHLLER--LFWLAVVVSSVIAALVLSRLQLERYFSSP-TVISVDR-DYRGWNGSLPAVTLCYYDHIDSFKANEYIQ-------------------EMWNVSIIDEDYFYFMDFLYAVVNATAGNYAELAKFAEDERFDQIDLYEMIQRVDRPFEQVISSFDAG------FQVHVQRVMTERGACYAINS-----------------------------------------------PMSTVLSGQPVAYELMPQPLSCQYGKQQCYIRMDLYESTGVLDVHSPFEVSATEANIVALHKSDEITASFKVLETVASKNLRQLSVAQRKCVFNNEETSNLKIY------SKSLCLARCRAVMALEMCNCV-PFFYPYVDGPS------CNPAGFECLL------------------DFKWPIWALHICKCPSTCTEIEYTMQT----VKKSSWGVKNNEEVAS--------------------------SETATSSFRWDLIPPKVRMRRDVVYSFEDLVVSFGGVLALFVGVSVMGLVEMVHVLVNNLLLDVFTLLRLMLGRLRRCWRRDDHMREANHHHHANAHAHAR---------------------LHDFNERLSLAATAELPPFDYVN-------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VL88-1", "uniprot_id": "Q9VL88_DROME", "id": "Q9VL88-1", "name": "", "aln": "--------------------------------------------------MARVEES----------YYRRLFREFLRQSYINGLHPFLYHTPVRYAKA--IWLAFLTAIMIYTHIVIADLILEYLVQP-TEIHMAPDLVHVANSPFPAVGVCTSNKINGRLLRSYAEKLFHHQGNSSLQAVALDLDDMANRLLVLAQFYLNPLESDHERWNATELDRLHRLLVAYHNGAGYSVRDILRDLSPGCGDLVIRGIVF-GLPVNASQLFLKRPTSSNVCCIFNYRRPSYS------------------------QFLTKRAEEDSEMRAVPMVVFESNSILNSVQFVLQDTPKEDITNTFHS--NSAFQLIIFPQEDYATIQSTTLGEVLVDHYSIVEIPIQPMFFSSGDGVRGVPPHIRRCYYPEEGMRLLNQS----YYSLDECLLVCRMKSMIDHCGCVSPPLTGSSMDLD-----YCMLPDLPCLMRWKSIWYG--YSDFAYLQNKEENLVQRQCEHCLPTCNGVSMSIT-------TNVAPLRRTYNSSGYFTGLLKGLTN---------------ERPLAIIKLFFKLRFAQATKSQMVSSWVVLLNRFGGILSLMYGFSIVSYIEILYYLTGKGFVYIYRSFLLDKEPINHNYS--------------------------------------------LYWRELRSNLPRQEQLRK----------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VJI4-1", "uniprot_id": "Q9VJI4_DROME", "id": "Q9VJI4-1", "name": "", "aln": "------------------------------------------------------------------------------------MGYWSETRAWLFRDP--AKLIRYLVLFACCIVVIVQLYECFAKLYNPPISTHSYYSLNETIEMPSVTICREPPYKEEVLTRLSG--------------------------------------------GACPHPKYATCWMKYPFGEISLDEFFENSTHDSGDTFVFYGLN--EDKNNVVMNSSLHFYMGRCYTLRP---------------------------------------------------KESAKRVSKAVGYSIMLEHSMLTTSVSDVDTGSVGWHVFIHDKKENFTEINMKGSGRVEYVFVGVNEEIEIKLQTQYFSNVQTREEACSDDEN------------YSDLKCGEQCIWQDLADNMQCSGPWMHEIASEPCN---DSLSMRKLIS------------------DYKDVYENEDDFDCDCVQPCQSRIYTTF------IQNRKAFN--------------------------------QPEPRTQIYIYYTTKLISMIEERPSYDTTQFIADVGGSLGFLLGLSVLGLIGILEHMMLFFCGGFIKRMQQKEQAKLEANSEDGQS--------------------------------------QTSDETIDVEIAYKKKEKQPKY-------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*. .* . . . * . . * * . *. .:: * *.. ", "identical_positions": 8, "similar_positions": 15, "identity": "1.07%" }, { "cls_id": "homologset.agr.MGI:1194921", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K2S5-1", "uniprot_id": "A0A0G2K2S5_RAT", "id": "A0A0G2K2S5-1", "name": "Dual specificity protein kinase TTK", "aln": "MEAEELIGRNLTIDSIMNKVRDIKNKIN-EDLTDELNSIKVCVDPT---ETVNQIMMVENTPENWLNFLLKLEKNSPPLND-ALLNKLIGRYSQAIEALPPDKYGQNESFARIQVRLAELKAIQEPDDAH-DYFQMARENCKKFAFVHVSFAQFELSQGNLKKSEQLLHKAVETGAVPLQMLETAIRNLHLQKKQLLSEEDKKSLSAS---------------------TVLTAQESFSSSLGN-------LQSRKSSCDPKV------------------QAAAARILYGENMPPKDAEVSHRNPLKQTNKTKRSCPFGRVPVNLLN---SPDYY------VKTDGSAVPQFTKRKISGSE------------------------------YRDSIMPG---------------SKSSGNDSY--------ELRGLKP------------------------------------IQAIHLKDSLVSNEKSSELMS-DLVTLKSKTDSS-LTKLEVSEPKVRQEPEIPERRHKQWQSARKPGCGIQ-NSAAFAPQWHVPDVTPK-ADKEQKCTTVEQLAFSVSKQSPPLSVPKWIDPKSVCETPSSSSLDDYMKCFKTSVVKN-EFPPACPSSTPYSQLARHQQHQQQGLSTPLQNLQISGSSSMSECISVNGRIYSILKQIGSGGSSKVFQVLNEKKQINAIKYVNLEDADSQTIDSYRNEIAYLNKLQQHSDKIIRLYDYEIT--DRYIYMVMECGNIDLNSWLKKKKS--INPWERKSYWKNMLEAVHTIHQHGIVHSDLKPANFLIVDGMLKLIDFGIANQMQPDTTSIVKDSQVGTVNYMAPEAIRDMSSS----RENGKIKTKISPRSDVWSLGCILYYMTYGKTPFQHIINQVSKLHAIIDPSHEIEFPEISEKDLRDVLKCCLVRNPKERISIPELLAHPYVQIQPHPGSQMAKETTDEMKYMLGQLVCLNSPNSILKAAKTLYERYNCGESQAPSSSKTSDKKRERE--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P35761-1", "uniprot_id": "TTK_MOUSE", "id": "P35761-1", "name": "Dual specificity protein kinase TTK", "aln": "MEAEELIGSSVTIDSIMSKMRDIKNKIN-EDCTDELSLSKICADHT---ETVNQIMRVGNTPENWLNFLLKLEKNSSPLND-DLLNKLIGRYSQAIEVLPPDKYGQNESFARIQVRLAELKAIQEPDDAR-DYFQMARENCKKFAFVHVSFAQFELSQGNLKKSEQLLHKAVETGAVPLQMLETAMRNLHLQKKQLLPEEDKKSVSAS---------------------TVLSAQEPFSSSLGN-------VQNRSISCESRG------------------QAGAARVLYGENLPPQDAEVRHQNPFKQTHAAKRSCPFGRVPVNLLN---SPDFY------VKTDSSAVTQLTTRLALSSVPLPYVTCLLHLQLLA-----LAGLAKGSGPDRDAILPG---------------SRPRGSDSY--------ELRGLKP------------------------------------IQTIYLKDSLVSNEKSSELMS-DLIALKSKTDSS-LTKLEETKP------EIAERRPMQWQSTRKPECVFQ-NPAAFAPLRHVPDVTPK-ADKE----------------SPPISVPKWLDPKSACETPSSSSLDDYMKCFKTPVVKN-DFPPACPSSTPYSQLARLQQQQQQGLSTPLQSLQISGSSSINECISVNGRIYSILKQIGSGGSSKVFQVLNEKKQINAIKYVNLEDADSQTIESYRNEIAFLNKLQQHSDKIIRLYDYEIT--EQYIYMVMECGNIDLNSWLKKKKS--INPWERKSYWKNMLEAVHIIHQHGIVHSDLKPANFVIVDGMLKLIDFGIANQMQPDTTSIVKDSQVGTVNYMAPEAIRDMSSS----RENSKIRTKVSPRSDVWSLGCILYYMTYGRTPFQHIINQVSKLHAIINPAHEIEFPEISEKDLRDVLKCCLVRNPKERISIPELLTHPYVQIQPHPGSQMARGATDEMKYVLGQLVGLNSPNSILKTAKTLYERYNCGEGQDSSSSKTFDKKRERK--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P33981-1", "uniprot_id": "TTK_HUMAN", "id": "P33981-1", "name": "Dual specificity protein kinase TTK", "aln": "MESEDLSGRELTIDSIMNKVRDIKNKFKNEDLTDELSLNKISADTTDNSGTVNQIMMMANNPEDWLSLLLKLEKNSVPLSD-ALLNKLIGRYSQAIEALPPDKYGQNESFARIQVRFAELKAIQEPDDAR-DYFQMARANCKKFAFVHISFAQFELSQGNVKKSKQLLQKAVERGAVPLEMLEIALRNLNLQKKQLLSEEEKKNLSAS---------------------TVLTAQESFSGSLGH-------LQNRNNSCDSRG------------------QTTKARFLYGENMPPQDAEIGYRNSLRQTNKTKQSCPFGRVPVNLLN---SPDCD------VKTDDSVVPCFMKRQTSRSE------------------------------CRDLVVPG---------------SKPSGNDSC--------ELRNLKS------------------------------------VQNSHFKEPLVSDEKSSELIITDSITLKNKTESSLLAKLEETKEYQ--EPEVPESNQKQWQSKRKSECINQ-NPAASSNHWQIPELARK-VNTEQKHTTFEQPVFSVSKQSPPISTSKWFDPKSICKTPSSNTLDDYMSCFRTPVVKN-DFPPACQLSTPYGQPACFQQQQHQILATPLQNLQVLASSSANECISVKGRIYSILKQIGSGGSSKVFQVLNEKKQIYAIKYVNLEEADNQTLDSYRNEIAYLNKLQQHSDKIIRLYDYEIT--DQYIYMVMECGNIDLNSWLKKKKS--IDPWERKSYWKNMLEAVHTIHQHGIVHSDLKPANFLIVDGMLKLIDFGIANQMQPDTTSVVKDSQVGTVNYMPPEAIKDMSSS----RENGKSKSKISPKSDVWSLGCILYYMTYGKTPFQQIINQISKLHAIIDPNHEIEFPDIPEKDLQDVLKCCLKRDPKQRISIPELLAHPYVQIQTHPVNQMAKGTTEEMKYVLGQLVGLNSPNSILKAAKTLYEHYSGGESHNSSSSKTFEKKRGKK--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8AYG3-1", "uniprot_id": "TTK_DANRE", "id": "Q8AYG3-1", "name": "Dual specificity protein kinase Ttk", "aln": "MDEEESTERQMQIAMLCQKLAMMKQLFN-EDDTDYIN-----------------QAISSNSPDTCRTFLSNLEKKGNPQADPSLLSKLMDSYTRVFSSMPLGKYSQNESYAKMLVRFAELKAIQDVNDAQ-TSFDIARSHCKDFAFVHVAYAQFELLQGNMKKCTMILQKAFEMNAKPRHVLEAAVRNLKTGKRQLLSHEDKENLSVSALDHTQGSRRSDGTCELKPSNTFLHSDQKFSPQEENGPVWRTGSQHRRTAMAERVPMVPLSIPENETSDSDCAQKAEAPFTHSSGFSRQTSGSSVRSAFSLCSSKKGTPDGDSYSLNIKPPVISPDYLREDIEEGHTITALLNRAEKRETARTEETTDINQIISTNSTEGCQAFLKNLEKRADPHSDAAFLSKLLDCYSKVFARFPLAEHCKTESYARMLVRYAELKGIEDPEDAADDFSIARSHCKAFAFVHIAHAQFELSRGNSRKSVSILQKALSSNARPIELLQTAIRNLKSGKTLLLPAEHQESSEAEN--VEAQNGMKREENPVKAPEDHQKPFSKETSSEWKIPALITKHTSPEDRKAPVEPVSSSSSHHAVRTPAPLRLNPSLSCQTPNYRQPNP--NSFVTPVVKQRPVIVSVPATAQKMCPTALPCTPQSGVSYIQPPTQTPSSAFSNESITIKGKQFFIFKMIGRGGSSKVYQVFDHKKHVYAVKYVNLEEADAQAVESYKNEIEHLNHLQQYSDQIIKLYDYEIT--SSYIYMLMECGHLDLNTWLRNRKT--VKPLDRKAYWRNMLEAVHTIHKHGIVHSDLKPANFLIVDGSLKLIDFGIANQIQPDVTSIMKDSQVGTLNYMPPEAIKDTSS-------NGKPGSKISAKGDVWSLGCILYCMTYGKTPFQNITNQISKIHAIIDPSHEIDFPDIPEKDLLDVLKKCLVRNPRERISIAELLDHPYLQLQPQPAPEPAETSSSDFKRILNELVALQSPNSIARAASNLAMMCNSGRKLDVSECVKSSSQTLWK--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KG66-1", "uniprot_id": "A0A0B4KG66_DROME", "id": "A0A0B4KG66-1", "name": "", "aln": "----------MTTPVPRRTKDMMALGLD------------------------------SDSEDDFNTPYRPRQAAAGERKQQPVASFQVQTRGKENEPHPLP-------INMLPRRVSELTMMDSDSDEE-DIKSNHNLNCAILNDSFVLSPSQELTNSNSN-----ITTRRTPSAAPLKQSDSNLSFLGRFNDMGINCSSQGSPVAN-------------------------SEKQVAKKTAP--------------------------------------TLQAAPSATERRPLQETETPLRNELPSTSKTKPDADFITPQVRTIG-------------------------------------------------------------------STLAG-------------------------------------------------------------------------------KSRSAVSNDFRAQKVLFQTPMTVSRAAPVA-----------------------------------------SDSISFSLCDTITE---------------------SPDIPEPPKKAEPPKSQHPSKKSLDH---VFRESDKDN------VPDKVDNVEPKELVSIPAVAVPPEQPSHKTSN------ILKIKNHEYTIDKKLGCGGSSSVFLARRSDSGNEFALKVVDLQADPQVVQGYLNETKLLAKLQGN-VCVVALYDYQLVREESKLYMVMEKGDCDLNKILQSYTTN-LPLYSLMNILYQMLQAVNYIHQHGVIHSDLKPANFLMVSGRLKLIDFGIASNIAVDSTSIIKFSQAGTFNYISPEALTDTSTGNSPMRRADQPKIKISTKSDVWSLGCILYLLLYQKTPFGHIRNVYAKMSAITTPGTSIEYPAIPP-----YYPIMLVHFTTVSALFADGQELPTVESQKAAVVHRTTTVPIPYDHSAAEPADTQQNRQQQLSTKAQLFISEMSKVKCLSHMCVYIFNSHFIVN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P54199-1", "uniprot_id": "MPS1_YEAST", "id": "P54199-1", "name": "Serine/threonine-protein kinase MPS1", "aln": "------MSTNSFHDYVDLKSRTNTRQFS------------------------------DDEEFTTPPKLSNFGSALLSHTEKTSASEILSSHNNDKIANRLEEMDRSSSRSHPPPSMGNLTSGHTSTSSHSTLFGRYLRNNHQTSMTTMNTSDIEINVGNSLDKSFERIRNLRQNMKEDITAKYAER---RSKRFLISNRTTKLGPAKR---------------------AMTLTNIFDEDVPN---------------------------------------SPNQPINARETVELPLEDSHQTNFKETKRNTDYDSIDFGDLNPIQYIKKHNLP-------TSDLPLISQIYFDKQREEN-------------------------------RQAALRKHS------------------------------------------------------------------------SRELLYKSRSSSSSLSSNNLLANKDNSITSNNGSQPRRKVSTGSS--------SSKSSIEIRRALKENIDTSNNSNFNSPIHKIYKGISR-------------------NKDSDSEKREVLRNISINANHADNLLQQENKRLKRSLDDAITNENINSKNLEVFYHRPAPKPPVTKKVEIVEPAKSASLSNNRNIITVNDSQYEKIELLGRGGSSRVYKVKGSGNRVYALKRVSFDAFDDSSIDGFKGEIELLEKLKDQ-KRVIQLLDYEMG--DGLLYLIMECGDHDLSQILNQRSGMPLDFNFVRFYTKEMLLCIKVVHDAGIVHSDLKPANFVLVKGILKIIDFGIANAVPEHTVNIYRETQIGTPNYMAPEALVAMNYTQNSENQHEGNKWKVGRPSDMWSCGCIIYQMIYGKPPYGSFQGQN-RLLAIMNPDVKIPFPEHTSNN---------EKIPKSAIELMKACLYRNPDKRWTVDKVLSSTFLQPFMISGSIMEDLIRNAVRYGSEKPHISQDDLNDVVDTVLRKFADYKI-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :. : : . : . ..:*. . . . : : .. *: .* . . : : .. : . . :. : . :. . . .. . ::: :. : : . : : . . . : :.::. : : :* **** *: . . * * . ::.: .* * :*: :: * **:: . :*::** *. **. *.. . : :** .:: :*. *::*********::*.* **:******. : . ..: : :* ** **:.***: . *:. .*:** ***:* : * :.*: : . :: ** * .* :* . : . : . : : : : . . . : ", "identical_positions": 70, "similar_positions": 140, "identity": "6.88%" }, { "cls_id": "homologset.agr.MGI:1194924", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LDN3-1", "uniprot_id": "A0ABK0LDN3_RAT", "id": "A0ABK0LDN3-1", "name": "CD180 antigen", "aln": "----------------------------MALDISCFLLVALFSASCQAIGSSDQRCTEKEVNKTYNCEHLGLSEIPGTLPNSTESLEFSFN-----------------------ALPTIQKTTFSRLVNLTFLDLTRCQIYWIHEDTFQSQHRLETLVLTANPLIFMAETALTGPKALKHLFFIQTGISSIEFIPVHSQKALESLYLGSNHISSIRLPKDFPTEKLKVLDFQNNAIHHLS---------------KEDVSSLQQATNLSLNLNGNDITGIEPGAFKSTV-----FQSLNFGGTQ---SLLVIFKGLQNSTIQSLWLGTFEDIDDD------EDISSSMFEGLCEMSVERIN------------------LQKHHFFNITSNTFYCFSG---------LQELDLTATHLTELPSGIVGLSKLKKLVLSANKFEN--------LCQISASNFP------------SLTHLYIKGNTKRLELGSGCLETLEH-----------------LRELDLSHDDIETSD-CCNLQLRNLSHLQS--------------------LNLSYNEPLGLRTEAFKECPQLELLDLAFTRLHVKDAQSPFQNLHLLKVLNLSHCLLGSSN-QHLLDGLPALRHLNLQGNRFPN---GNIQKTNPLQALGSLEILILSF-----CDLSSIDHQAFINLKIMNHVDLSHNRLTSSSIEALSHLKGIYLNLAS---NRISIIPP---SLLPVLSQQRTINLRQNPLDCTCSN----------IYFLEWYKENMQKLEDIEDTFCANPPLLRGVKVSDVMLSCSMAA-VGIFFLIVFLLLFAVLLIFAVKRFLRW--KYQHI----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q62192-1", "uniprot_id": "CD180_MOUSE", "id": "Q62192-1", "name": "CD180 antigen", "aln": "----------------------------MAPDISCFFLVALFLASCRATTSSDQKCIEKEVNKTYNCENLGLNEIPGTLPNSTECLEFSFN-----------------------VLPTIQNTTFSRLINLTFLDLTRCQIYWIHEDTFQSQHRLDTLVLTANPLIFMAETALSGPKALKHLFFIQTGISSIDFIPLHNQKTLESLYLGSNHISSIKLPKGFPTEKLKVLDFQNNAIHYLS---------------KEDMSSLQQATNLSLNLNGNDIAGIELGAFDSAV-----FQSLNFGGTQ---NLLVIFKGLKNSTIQSLWLGTFEDMDD-------EDISPAVFEGLCEMSVESIN------------------LQKHYFFNISSNTFHCFSG---------LQELDLTATHLSELPSGLVGLSTLKKLVLSANKFEN--------LCQISASNFP------------SLTHLSIKGNTKRLELGTGCLENLEN-----------------LRELDLSHDDIETSD-CCNLQLRNLSHLQS--------------------LNLSYNEPLSLKTEAFKECPQLELLDLAFTRLKVKDAQSPFQNLHLLKVLNLSHSLLDISS-EQLFDGLPALQHLNLQGNHFPK---GNIQKTNSLQTLGRLEILVLSF-----CDLSSIDQHAFTSLKMMNHVDLSHNRLTSSSIEALSHLKGIYLNLAS---NRISIILP---SLLPILSQQRTINLRQNPLDCTCSN----------IYFLEWYKENMQKLEDTEDTLCENPPLLRGVRLSDVTLSCSMAA-VGIFFLIVFLLVFAILLIFAVKYFLRW--KYQHI----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99467-1", "uniprot_id": "CD180_HUMAN", "id": "Q99467-1", "name": "CD180 antigen", "aln": "----------------------------MAFDVSCFFWVVLFSAGCKVITSWDQMCIEKEANKTYNCENLGLSEIPDTLPNTTEFLEFSFN-----------------------FLPTIHNRTFSRLMNLTFLDLTRCQINWIHEDTFQSHHQLSTLVLTGNPLIFMAETSLNGPKSLKHLFLIQTGISNLEFIPVHNLENLESLYLGSNHISSIKFPKDFPARNLKVLDFQNNAIHYIS---------------REDMRSLEQAINLSLNFNGNNVKGIELGAFDSTI-----FQSLNFGGTP---NLSVIFNGLQNSTTQSLWLGTFEDIDD-------EDISSAMLKGLCEMSVESLN------------------LQEHRFSDISSTTFQCFTQ---------LQELDLTATHLKGLPSGMKGLNLLKKLVLSVNHFDQ--------LCQISAANFP------------SLTHLYIRGNVKKLHLGVGCLEKLGN-----------------LQTLDLSHNDIEASD-CCSLQLKNLSHLQT--------------------LNLSHNEPLGLQSQAFKECPQLELLDLAFTRLHINAPQSPFQNLHFLQVLNLTYCFLDTSN-QHLLAGLPVLRHLNLKGNHFQD---GTITKTNLLQTVGSLEVLILSS-----CGLLSIDQQAFHSLGKMSHVDLSHNSLTCDSIDSLSHLKGIYLNLAA---NSINIISP---RLLPILSQQSTINLSHNPLDCTCSN----------IHFLTWYKENLHKLEGSEETTCANPPSLRGVKLSDVKLSCGITA-IGIFFLIVFLLLLAILLFFAVKYLLRW--KYQHI----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1P6U9-1", "uniprot_id": "A0A8M1P6U9_DANRE", "id": "A0A8M1P6U9-1", "name": "", "aln": "------------------------MESFFVFYMSFYSILFHFLVFNEATPWARRHC--QQITKGYDCNDMDLQSIPDEIPNSVQILQFSFN-----------------------YLPALYNSTFQRLKSLRSLDVTRCSITFIYEDVFTYQPHLEVLLLTGNPLVFIASTAFSGPLALKYLSLVQSKIKQLSDIPSENLAYLEVLDLRGSNIRSLNGLSNFRWQNLKSLQLDLNFIDRIS---------------FNDLQPFSNLAGVSISFKGNDFIYIEPGAFHSLN-----LSSLDFSGCLNKMNISSLLKGLEGIKTNRLNLGLYETDSN-------VYIASAALQSFCNIFVSDLD------------------FQLQHFLDLNNSTFHCLEG---------LKKLDLTRAHLNALPLNTTGLSTLSHLILDENQFKD--------VCQSNTRNFP------------MLTHLSISGNLKKLTFSNRCLDSLGL-----------------LEELDLSVSLVNPREPCCNNQLFGLGELKL--------------------LNLSYGSPMFWSSKPFNVTPKLEHLDFSHSVYTLLNDSSPFSNLQSLRTLNLSWSNTDLTN-VHLFVGLKALQHLNLRGNAIQG---EVLTQTELFKCVPLLETLVLSA-----CKITSFDENLFKGLRHLNHIDLSENKFVKLSTSGFYSLDFLKLNFAR---NDITTVDV---ASVADLGEEGSVDLSYNPLVCNCSN----------FEFIHWVKKNKVKVKHLMETFCNG----TGTRIIDAKLQCDLPVGVLVFCAVLAAVLLASAIFLLIRRVRKYS-IYTNL----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A6M3Q7U5-1", "uniprot_id": "A0A6M3Q7U5_DROME", "id": "A0A6M3Q7U5-1", "name": "", "aln": "--------MPDHTRVTATTRSRPWLCGAIPVLLLLLLTLVILPPETTAFCPSKCQCLGGEANSRALCVDAALEDVPIQLNPETKYINLTVNRIRTLEFSLPFYMKLEILDLSQNIIETLGSKNFEYQSELRTLNLSRNLVSSLHKHAFKGLTNLLLLDLSFNRIETVHPTALSDLASLVELDLTNNNIVSLEDNCFKGMNTLEVLVFRNNRLLDVPASNLWHLHALKSLDMSLNLVEFVR---------------NDSFEGLKELLALSV--QGNVMSELDLSAFEGLIS----LKHLDLSDNNLTMVPTQQLSKLSNLTYLNLGGNRFSQLPAV------AFLNLFHLRELHLSRLDFLQRIDSRAFVDNTHLQTLHLNNNPQLSDIPMRLFQGNPN---------ILEVYMQSNSLQTLYSAQFPVDQLQKLYLGDNPLQCNCS--LLWLWRLVTGNFEGVDPGMEHAAGGAVAALAKEADDEELADEATAVASTDDGVAALAAYIAEQHIVNALHTTEPSAYELATSSSNRNSGILRMDRQQIGCD--------------IWRDKVRTRRKLLTMSEGEITCPAHIVTVVCAVITCLLVAMIGISVLYYLRFVKRRRKLLHERGPMRTSKSIINVHDRILQGHNPGG---LGLGMSMTLGGGNHVNGLGMTLNYPHHAQTLQAHHHYHQAMPLQSHGGNGNHEYQQTTLPQLDKLELERYLAAQTIANEYRALKP---WELPVKEADDEPEHLYERFDHYEYP----------DTHTMSKLKQAASLNHSNSSAGPSPVPPSSGKPHVVYVXRGRGTGERVSQINTDIEMVGLNHLHLHHHHHNNNNNYRGCVQSAKASGQF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VS84-1", "uniprot_id": "Q9VS84_DROME", "id": "Q9VS84-1", "name": "", "aln": "MTSLVYTVFHLASLQCSVRPEISPCTCETGKAWNHVELSCEKLESFNAVVDSLANKLNADTNIDLKITHSQLDDLEMRSFTDMNFNLYKLRMQWN-------------------SLKSLPEVPFRGLSNVTYLSIGDNDLDEIPKHALSHMPSLLTLDIGRCKIRAVQQEDFRGIQRVTNLILVSNIITRLDRGSFP--KSLLILHLGRNQLESLNG-SLHDLHNLESLFINANNITSLDDELPDGGQLRLLMAHNNRLERLPANMAGMHSLETVHIHCNQLRSFDRVLRNAVNLSEVMADNNELEYLAQDEFASCSKVETLQMGCNHIKSLNSSLLPILKLKNANFSFNDIEEFSMAELHG-----------------LRSLKTLQLSSNRIQRLLPDPRGVQELMLVNLDLDNNRIDSLNGALAGLGNLRILNLAGNRLEHLQVGDFDGMIRLDILDLTG-----NQLAELKPLEMTLLPSLKILKVAYNNITKLEQDFKGLPVLCQAN---LTNNQISTISSELVTNTRCKNHNVPGKLEIHLDDNPIMCDVGLNELCRLMAVQEARIRGRSQCFENDQEVCTVLPMLYNVNLPIMVTNLKLTGREVPKPMVRVIVPSLIKANN-ELLPPLIATLGNPVLISTDLVNPVISPLPPPLLLATTTPPPPLPLPVESEVEKNESTTANPVPTNYTQETTTTTSTTTTTTTTETSSQVAPIEIITTTAPTTTTTSTTTPKPNETLPVIVELQDPNPPDTTVNQTALVPPVVLDPLQQDLERERERERERELERDLDHEAVAKTEYETVEYIPNLVQPPVGSDALTPPPSKANALEEDSESVHSNSVHAEYPHAAQSLQIPEEPPEE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . . *..: : ... : :: . * .: *.: : : :..: * * : : : : . : * : .. * :. * * : ..: .: . . *: * :. * : : : . : : . : :*. :. : .. : . : . . :. : : :. . :: : : :: : : * :. * * * * :. : : :: : . : * : . . . : . . : . : : : . : : . : : . * . : . : * :. . . . : : . :. : . :. .:: . . : : . ", "identical_positions": 21, "similar_positions": 138, "identity": "2.43%" }, { "cls_id": "homologset.agr.MGI:1194993", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K230-1", "uniprot_id": "A0A0G2K230_RAT", "id": "A0A0G2K230-1", "name": "", "aln": "----------------------------MAMAMAVPELRS---LPYRAPFTKFLLTLWVFSFVG-EACKDVTFYVPSTLEADKIIGRVSLKECLSSADGIMPSDPDFRVLDDGSVYPTRAVVLSDEKRSFTIQLSDSKMRKQKEITVILERQKEVMMKRHTNETVLRRAKRRWAPIPCSMQENSLGPFPLFLQQVQSDSAQNYNIFYSISGRGVDQEPLNLFFIERDTGNLYCTRPVDREEYDVFDLIAYASTADGYSADLPLPLPIKVEDENDNYPLFTEAIYNFEVPESSRLGTVVGTVCATDKDEPDTMHTRLKYSILEQSPPSPGLFSVHPDTGVITTVSHYMDREVVDKYKLILKVQDMNGQFFGLISTSTCIITVQDSNDNAPTFRQNAYETSVEENTYNVEILRIPVDDKDMVNSANWKANFTILKGNENGWFKITTDPATNEGVLCVVKPLDYEENRQVTLEIGVNNEAPFIRDVASRIPTMNRAMVTVQVRDQNEGPECKPREQIVRIKENSAIGSKINGYKAYDPETKNSNGLRYKKLQDPKDWVSIEEVSGSLTISKILDREIMAPRNDLYNITVMAIDQEGRSCTGTLAVNIEDMNDNAPEIIQDDIVICKP--RMGYTDISAVDPDEPIHGPPFQFALASSSPEVNRIWTLNQVNDTAARLSYQKTADVQIYSVPVTVTDRAGQSATKILRVNLCDCTHPSQCL--LRSRRAGITLGKWAILAILLGIALLFSVLLTLVCGVVTAQKGKHFPEDLAQQNLIISNTEAPGDDRVCSANGFTTHTANNSSQGFCGTMGSG---MRNGGQETIEMMKG-HQTLDSCRVAGHHHTLDSCRGGHMETDN-CRYTYSEWHSFTQPRLG-----EKLHVCNQNEDHIPSQDYVLTYNYEGRGSPAGSVGCCSEKQEEEGLDFLNNLEPKFLTLAETCTKR-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P55850-1", "uniprot_id": "DSC3_MOUSE", "id": "P55850-1", "name": "Desmocollin-3", "aln": "--------------------------------MVVPEFRS---PQCRALCTKLLLTLWVFSFVG-EACKKVTFHVPSTLEADKIIGRVSLKECLSSADGIMPSDPDFRVLDDGSVYPTRAVVLSDEKRSFTIQLSDSKMQTQKEIPVILEHKKKVLKKRHTKETVLRRSKRRWAPIPCSMQENSLGPFPLFLQQVQSDAAQNYTVFYSISGRGADQEPLNWFFIERDTGNLYCTRPVDREEYDVFDLIAYASTADGYSADLPLPLPIKIEDENDNYPLFTEAIYAFEVPEGSRLGTVVGTVCATDKDEPDTMHTRLKYSILEQTPPSPGLFSVHPDTGVITTVSHYMDREVVDKYKLIMKVQDMNGQFFGLISTSTCIITVQDSNDNAPTFRQNTYETAVEENTYNVEILRIPVDDKDMINTANWKANFTILKGNENGWFKITTDPVTNEGVLCVVKPLDYEENRQVTLEIGVNNEAPFIKDVANRIPTMNRAMVTVHVKDQNEGPECKPPEQYVRIKENSAVGSKINGYKAYDPETKNSNGLRYKKLQDPKDWVSIEEVSGLLTISKTLDREIMAPRNDMYNITVMAIDQEGKSCTGTLAVNIEDVNDNAPEIIQDYIVICKP--KMGYTDISAVDPDEPIHGPPFQFNLANTSPEVNRIWTLNQVNDTAARLSYQKTADVQIYNVPVTVKDRAGQSATKILRVNLCDCTHPSQCP--LRSRSAGITLGKWAILAILLGIALLFSVLLTLVCGVVTARKGKHFPEDLAQQNLIISNTEAPGDDRVCSANGFTTHTANNSSQGFCGTMGSG---MRNGGQETIEMMKG-HQTLDSCRVAGHHHTLDSGRGGHMDTDN-CRYTYSEWHSFTQPRLG-----EKLHVCNQNEDHIPSQDYVLTYNYEGRGSPAGSVGCCSEKQEEEGLDFLNNLEPKFLTLAETCTKR-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14574-1", "uniprot_id": "DSC3_HUMAN", "id": "Q14574-1", "name": "Desmocollin-3", "aln": "--------------------------------MAAAGPRR---SVRGAVCLHLLLTLVIFSRAG-EACKKVILNVPSKLEADKIIGRVNLEECFRSADLIRSSDPDFRVLNDGSVYTARAVALSDKKRSFTIWLSDKRKQTQKEVTVLLEHQKKVSKTRHTRETVLRRAKRRWAPIPCSMQENSLGPFPLFLQQVESDAAQNYTVFYSISGRGVDKEPLNLFYIERDTGNLFCTRPVDREEYDVFDLIAYASTADGYSADLPLPLPIRVEDENDNHPVFTEAIYNFEVLESSRPGTTVGVVCATDRDEPDTMHTRLKYSILQQTPRSPGLFSVHPSTGVITTVSHYLDREVVDKYSLIMKVQDMDGQFFGLIGTSTCIITVTDSNDNAPTFRQNAYEAFVEENAFNVEILRIPIEDKDLINTANWRVNFTILKGNENGHFKISTDKETNEGVLSVVKPLNYEENRQVNLEIGVNNEAPFARDIP-RVTALNRALVTVHVRDLDEGPECTPAAQYVRIKENLAVGSKINGYKAYDPENRNGNGLRYKKLHDPKGWITIDEISGSIITSKILDREVETPKNELYNITVLAIDKDDRSCTGTLAVNIEDVNDNPPEILQEYVVICKP--KMGYTDILAVDPDEPVHGAPFYFSLPNTSPEISRLWSLTKVNDTAARLSYQKNAGFQEYTIPITVKDRAGQAATKLLRVNLCECTHPTQCR--ATSRSTGVILGKWAILAILLGIALLFSVLLTLVCGVFGATKGKRFPEDLAQQNLIISNTEAPGDDRVCSANGFMTQTTNNSSQGFCGTMGSG---MKNGGQETIEMMKGGNQTLESCRGAGHHHTLDSCRGGHTEVDN-CRYTYSEWHSFTQPRLG-----EKLHRCNQNEDRMPSQDYVLTYNYEGRGSPAGSVGCCSEKQEEDGLDFLNNLEPKFITLAEACTKR-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QSQ0-1", "uniprot_id": "DSC2L_DANRE", "id": "F1QSQ0-1", "name": "Desmocollin 2-like protein", "aln": "MRTPPRPEGLYPSPTVRYTQFMVETGHIQLLQITYPHTHSRFRMYERAHFAACLLALVLFQRAESCDPRPVLVQVPNTVPAGYFITQVTLNGCTAIPVSFTSSDPDFTVNTDGSIVTLRSLVISTKR--FSVLVQDNSGLDWR-VEIILSCKNEDSQK--SGSVAQKRAKRRWRPLPFSVVENASPPFPKDVEMIASDSSVNYTVHYVISGQGVTEEPIGLFQLDQKTGMVRVTGPVDREKNPEFNFIARAFDQNNREVDQFLPITVMVEDVNDNAPEFTGNRF-FTVEERCRAGTRVGQVNATDRDQPKTPHSLIKYILLN----ATDMFSIDQSTGIITAKSNTLDREAQDKVFVGVEIRDMGGAPNGLFNRGTAVISLTDVNDNPPTFKEKLYKGTIKENLANVLVTRIPVEDKDLVNTPNWKAVYEVTKGNENGNFRMETDPKTNEGLLYVVKGLDFEKTPVMNLEVTARNEAPLVGTDAKWQSVP----LQLNVEDVDEGPEFNPNIMYLKVKENLPNGTVIGTYKALDPETKNSNGIKYYKLTDPGNWITVVESTGELKVANTIDRESSLVHNDTYNITIKAVDESKKTGNGVVILQIEDVNDNIPVIQRPDLNMCNRGDAVSSVLVEAVDQDKPPYSTPFIFELG---AEQEGKWKLKDITDSSVVLQQVEPMPNGMYTVPITVKDLQGTGKEQIVNVRVCSCQREDSGVGICGARSASVSLGNYGILALVLSGLLLLLLCLFLIFFCTTKRDKLQITDDTGTGGILLKSNTEAPGEEVKDGTLLLIPTADVVDGSFQSAVTESKNVNTAPGRYGQQFFQSGGVYNTTTQEFGTDQYYTSGRYDNKIYGNGTLQKFSNTGTLDTWRTNGCYLDRKLAYFGEQEDGRYADDLLKNYGNEGVGSSAGSVGCCSILGEQESMEFLNTLGPKFRPLADICYTTNKTGK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. . : * **:* :*. . : * . **..: *. :* :*.*: * . : .***** * ***: . *::.:* :: *:: :.*. : : ::*. ::: . : ... :*:**** *:* *: **: *** :: : **:: **.:.* ***:*. :**:. * :::.** : * *****: *::** * :. ..* **:.: :** *** * ** : * * * .* ** ** * ***:*:*.* *: :** :*: :..:**:. .**:**: *: :***. ** : ::::**.* **:. .*.:*:: * ***.***::: *: ::** ** : ***::***::*:.**:. : : ****** *:: ** ****:* *** *::*:. :.**: ..****: . .. : ::*.* :**** .* :::*** . *: *. *** ***.:*.**::* ** ** .*::: * :* : :: :*** :*: ****: *:*:. :: .*.: ::***:*** * * : : :*: :. . : *** *:* :..** * * .* . *.*..:.*::. *. : *.:*:**.* * . :::.*.:*.* : . :* :.: **::.***::*. **: : * *: . ::.:* . .:::... . .:.* ... : *:: . .* .:: .. *: ::::. : : * .: * * .: .* .:*: :: * . .** .::** ::* : .*. ** **.******** *::.::***.* *** .**: * . ", "identical_positions": 282, "similar_positions": 308, "identity": "29.65%" }, { "cls_id": "homologset.agr.MGI:1195256", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P50392-1", "uniprot_id": "PA24A_DANRE", "id": "P50392-1", "name": "Cytosolic phospholipase A2", "aln": "MS------NIIVEHQYSHRLKLTVVRAENVTKGAFGDLLDTPDPYVELSVPTTPESRKRTRHINNDINPKWNETFEFILDPNQSNVLEVTLMDANYVMDETLGTAKYSLSKLKVAQMEHVTLSIGKTTKVFLDLLLEVCASTDLRFSMTLCDQEKLFMQTRRDRVMLSIKKLLKMENPRFLPSSPREVPTIAILGSGGGFRAMVGFSGVMKALYESGVFDCATYVAGLSGSTWYMSMLYSHPEFPAKGPGDINKELMNRVSNNPLKLLLPQNINRYVKALWKKKSAGQPVTFTDIFGMLIGETLIPGR-----MNIKLSSLKGK---INEGQSPLPLFTCLHVKPDVSELMF-ADWVEFSPYEIG--MAKYGTFMSPGLFGSKFFMGSVVKQYEENPLHFLMGVWGSAFSILFNRVLGVKE------------TTS-SSTMEEELEQIKPEHIVG-DDSADNEEETQRG-GTESADAEDERQRHAQASWVQRMLTSIMGDTTLFTTREGRAGKVHNFMLGLNLNSTLPFSPFSGITHQTSLEE-EVDA-VTDPDEFERIYEP-LDVKSKKIHVVDSGLTFNLPYPLILRCQRGVDLIISFDFSARPSDSSPPFKELLLAEKWARMNKLPFPKIDSKVFDREGLKECYVFKPAKG----DKNCPTIIHFVLANINFRNFKAPGVPRDSDKDIEFGDFDIFD-------------------EPASPYSTFNFKYNNQAFKRLHDLMEFNTLNNIEVIKEAIKDSILLRRENPARCSVSLSLSEIE---NKKFLKRDNSIAKRPT", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M6YV03-1", "uniprot_id": "A0A8M6YV03_DANRE", "id": "A0A8M6YV03-1", "name": "Phospholipase A2", "aln": "MSTAD--HHIFVEQQISHKFKVKVLRAENVTKGALGDLLDTPDPYVELFIPTSPESRKKTRHIDNDINPEWNETFEFILDPNQDNVLKLTLMDANYVVDETLGTASYDISKLKVGQTMLVSFLIGKMTNVFLELSLEECLAMDLRFNLDLCPKEKLYRQHRRDKVMLAIKKLLNIEKPSSLPCSPHEVPVIAVLGSGGGFRAMIGFSGVMKALYISGVLDCVTYVAGLSGSTWYMSTLYSHPEFPTKGPEQINQELMNSVSSNPLRLLHPKHITNYIHALWSKKTTGQPVTFTDIFGMLIGETLIPAR-----MDTKLRDLQEK---INEAQAPLPLFTCLHVKPDVSELKF-ADWVEFSPYEIG--MAKYGTFMTPDLFGSKFFMGNVVKKHEENPLHFLMGVWGSAFSILFNRILGLTD------------VTN-GSTMEEELEQIKPEHIVG-EDSLDNDEDPHK---------EDE----HQASWIQRMVGSLFSDSVLFNTREGRAGKVHNFMLGLNLNNDVPFSPYT--ETISCTED-EVDA-VTDPFEFDRIYEP-LDVKSRKIHVVDSGLTFNLPYPLILRPQRGVDLIISFDFSARPSDSSPPFKELLLAEKWARMNKLPFPKIDPKVFDREGLKECYVFKPKKG----ERNCPTIIHFVLVNIEFRKFKAPGVPRGSDKEREFADFDIFD-------------------DPQTPYSTFNFYYSHQAFTQLHDLMEFNTLNNIEVIKEGIKDSILYRKEIPSRCSASLSLSEAQ---KKKRLKK---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P47713-1", "uniprot_id": "PA24A_MOUSE", "id": "P47713-1", "name": "Cytosolic phospholipase A2", "aln": "MSFIDPYQHIIVEHQYSHKFTVVVLRATKVTKGTFGDMLDTPDPYVELFISTTPDSRKRTRHFNNDINPVWNETFEFILDPNQENVLEITLMDANYVMDETLGTATFPVSSMKVGEKKEVPFIFNQVTEMILEMSLEVCSCPDLRFSMALCDQEKTFRQQRKENIKENMKKLLGPKKSEGLY-STRDVPVVAILGSGGGFRAMVGFSGVMKALYESGILDCATYIAGLSGSTWYMSTLYSHPDFPEKGPEEINEELMKNVSHNPLLLLTPQKVKRYVESLWKKKSSGQPVTFTDIFGMLIGETLIQNR-----MSMTLSSLKEK---VNAARCPLPLFTCLHVKPDVSELMF-ADWVEFSPYEIG--MAKYGTFMAPDLFGSKFFMGTVVKKYEENPLHFLMGVWGSAFSILFNRVLGVSG------------SQNKGSTMEEELENITAKHIVS-NDSSDSDDEAQGPKGTENEEAEKEYQSDNQASWVHRMLMALVSDSALFNTREGRAGKVHNFMLGLNLNTSYPLSPLRDFSSQDSFDD-ELDAAVADPDEFERIYEP-LDVKSKKIHVVDSGLTFNLPYPLILRPQRGVDLIISFDFSARPSDTSPPFKELLLAEKWAKMNKLPFPKIDPYVFDREGLKECYVFKPKNPDV--EKDCPTIIHFVLANINFRKYKAPGVLRETKEEKEIADFDIFD-------------------DPESPFSTFNFQYPNQAFKRLHDLMYFNTLNNIDVIKDAIVESIEYRRQNPSRCSVSLSNVEARKFFNKEFLSKPTV------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P50393-1", "uniprot_id": "PA24A_RAT", "id": "P50393-1", "name": "Cytosolic phospholipase A2", "aln": "MSFIDPYQHIIVEHQYSHKFTVVVLRATKVTKGTFGDMLDTPDPYVELFISTTPDSRKRTRHFNNDINPVWNETFEFILDPNQENVLEITLMDANYVMDETLGTATFPVSSMKVGEKKEVPFIFNQVTEMILEMSLEVCSCPDLRFSMALCDQEKTFRRQRKENIKENMKKLLGPKKSEGLY-STRDVPVVAILGSGGGFRAMVGFSGVMKALYESGILDCATYVAGLSGSTWYMSTLYSHPDFPEKGPEEINEELMKNVSHNPLLLLTPQKVKRYVESLWKKKSSGQPVTFTDIFGMLIGETLIQNR-----MSTTLSSLKEK---VSAARCPLPLFTCLHVKPDVSELMF-ADWVEFSPYEIG--MAKYGTFMTPDLFGSKFFMGTVVKKYEENPLHFLMGVWGSAFSILFNRVLGVSG------------SQNKGSTMEEELENITAKHIVS-NDSSDSDDEAQGPKGTENEDAEREYQNDNQASWVHRMLMALVSDSALFNTREGRAGKEHNFMLGLNLNTSYPLSPLRDFSPQDSFDDDELDAAVADPDEFERIYEP-LDVKSKKIHVVDSGLTFNLPYPLILRPQRGVDLIISFDFSARPSDTSPPFKELLLAEKWAKMNKLPFPKIDPYVFDREGLKECYVFKPKNPDV--EKDCPTIIHFVLANINFRKYKAPGVLRETKEEKEIADFDIFD-------------------DPESPFSTFNFQYPNQAFKRLHDLMYFNTLNNIDVIKDAIVESIEYRRQNPSRCSVSLSNVEARKFFNKEFLSKPTAESI---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P47712-1", "uniprot_id": "PA24A_HUMAN", "id": "P47712-1", "name": "Cytosolic phospholipase A2", "aln": "MSFIDPYQHIIVEHQYSHKFTVVVLRATKVTKGAFGDMLDTPDPYVELFISTTPDSRKRTRHFNNDINPVWNETFEFILDPNQENVLEITLMDANYVMDETLGTATFTVSSMKVGEKKEVPFIFNQVTEMVLEMSLEVCSCPDLRFSMALCDQEKTFRQQRKEHIRESMKKLLGPKNSEGLH-SARDVPVVAILGSGGGFRAMVGFSGVMKALYESGILDCATYVAGLSGSTWYMSTLYSHPDFPEKGPEEINEELMKNVSHNPLLLLTPQKVKRYVESLWKKKSSGQPVTFTDIFGMLIGETLIHNR-----MNTTLSSLKEK---VNTAQCPLPLFTCLHVKPDVSELMF-ADWVEFSPYEIG--MAKYGTFMAPDLFGSKFFMGTVVKKYEENPLHFLMGVWGSAFSILFNRVLGVSG------------SQSRGSTMEEELENITTKHIVS-NDSSDSDDESHEPKGTENEDAGSDYQSDNQASWIHRMIMALVSDSALFNTREGRAGKVHNFMLGLNLNTSYPLSPLSDFATQDSFDDDELDAAVADPDEFERIYEP-LDVKSKKIHVVDSGLTFNLPYPLILRPQRGVDLIISFDFSARPSDSSPPFKELLLAEKWAKMNKLPFPKIDPYVFDREGLKECYVFKPKNPDM--EKDCPTIIHFVLANINFRKYRAPGVPRETEEEKEIADFDIFD-------------------DPESPFSTFNFQYPNQAFKRLHDLMHFNTLNNIDVIKEAMVESIEYRRQNPSRCSVSLSNVEARRFFNKEFLSKPKA------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P39105-1", "uniprot_id": "PLB1_YEAST", "id": "P39105-1", "name": "Lysophospholipase 1", "aln": "---------------MKLQSLLVSAAVLTSLTENVNAWSPN-NSYVPANVTCD-DDINLVREASG-------------LSDNETEWLKKRDAYTKEALHSFLNRATSNFSDTS-----LLSTLFGS-NSSNMPKIAVACSGGGYRAMLSGAGMLAAMDNRTDGANEHGLGGLLQG------------------------------------ATYLAGLSGGNWLTSTLAWNNWTSVQAIVDNTTESNSIWDISHSILTPDGIN--IFKTGSRWDDISDDVQDKKDAGFNISLADVWGRALAYNFWPSLHRG-GVGYTWSTLREADV-FKNGEMPFPITVADGRYPGTTVINLNATLFEFNPFEMGSWDPTLNAFTDVKYLGTNVTNGKPVNKGQCIAGFDNTGFITATSSTLFNQFLLRLN------------STDLPSFIANLATDFLEDLSDNSDDIAIYAPNPFKEANFLQKNATSSIIESEYLFLVDGGEDNQNIPLVPLLQKERELDVIFALDNSADTDDYWPDGASLVNTYQRQFGSQGLNLSFPYVPDVNTFVNLGLNKKPTFFGCDARNLTDLEYIPPLIVYIPNSRHSFNGNQSTFKMSYSDSERLGMIKNGFEAATMGNFTDDS----DFLGCVGCAIIRRKQQNL--NATLPSECSQCFTNYCWNGTIDSRS---VSG------------------------------VGNDDYSSSASLSASAAAASASAS--------ASASASASASGSSTHKKNAGNALVNYSNLNTNTFIGVLSVISAVFGLI---", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q03674-1", "uniprot_id": "PLB2_YEAST", "id": "Q03674-1", "name": "Lysophospholipase 2", "aln": "---------------MQLRNILQASSLISGLSLAADSSSTTGDGYAPSIIPCPSDDTSLVRNASG-------------LSTAETDWLKKRDAYTKEALHSFLSRATSNFSDTS-----LLSTLFSS-NSSNVPKIGIACSGGGYRAMLGGAGMIAAMDNRTDGANEHGLGGLLQS------------------------------------STYLSGLSGGNWLTGTLAWNNWTSVQEIVDHMSESDSIWNITKSIVNPGGSN--LTYTIERWESIVQEVQAKSDAGFNISLSDLWARALSYNFFPSLPDA-GSALTWSSLRDVDV-FKNGEMPLPITVADGRYPGTTVINLNATLFEFTPFEMGSWDPSLNAFTDVKYLGTNVTNGKPVNKDQCVSGYDNAGFVIATSASLFNEFSLEAS------------TSTYYKMINSFANKYVNNLSQDDDDIAIYAANPFKDTEFVDRNYTSSIVDADDLFLVDGGEDGQNLPLVPLIKKERDLDVVFALDISDNTDESWPSGVCMTNTYERQYSKQGKGMAFPYVPDVNTFLNLGLTNKPTFFGCDAKNLTDLEYIPPLVVYIPNTKHSFNGNQSTLKMNYNVTERLGMIRNGFEAATMGNFTDDS----NFLGCIGCAIIRRKQESL--NATLPPECTKCFADYCWNGTLSTSANPELSGNSTYQSGAIASAISEATDGIPITALLGSSTSGNTTSNSTTSTSSNVTSNSNSSSNTTLNSNSSSSSISSSTARSSSSTANKANAAA-ISYANTNTLMSLLGAITALFGLI---", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q08108-1", "uniprot_id": "PLB3_YEAST", "id": "Q08108-1", "name": "Lysophospholipase 3", "aln": "-----------MIRPLCSKIIISYIFAISQFLLAANAWSPT-DSYVPGTVSCP-DDINLVREATS-------------ISQNESAWLEKRNKVTSVALKDFLTRATANFSDSSE----VLSKLFNDGNSENLPKIAVAVSGGGYRSMLTGAGVLAAMDNRTEGAYEHGLGGLLQS------------------------------------TTYLSGASGGNWLVGTLALNNWTSVQDILNNMQNDDSIWDLSDSIVTPGGIN--IFKTAKRWDHISNAVESKQNADYNTSLADIWGRALAYNFFPSLNRG-GIGLTWSSIRDFPV-FQNAEMPFPISVADGRYPGTKVINLNATVFEFNPFEMGSWDPSLNSFANVKYLGTNVSNGVPLERGKCTAGFDNAGFIMGTSSTLFNQFLLRIN------------STHLPSFITRLARHFLKDLSQDFNDIAVYSPNPFKDTKFLDSDYTTSIVDSDSLFLVDGGEDDENVPVLPLIQKERDVDIIFAVDNSADMRLAWPDGSSLVHTYERQFVKQGQGMSFPYVPDTNTFVNLGLNKKPTFFGCDANNLTDLQYIPPLVVYLPNAEYSFNSNQSAFKLSYSESQRRSMIQNGFEIATRNNFTDDP----EFMGCVGCAIIRRKQQAL--NITLPPECETCFKNYCWNGTLDTTPLPDVEKDVHHSFINVN--------------------SFNSSIGQEESLYAGSSASQSSSS-----SSSSSSSSEIPSATATLEKKAATNSGSHLSGISVKFSAMIMLTLLMFTGAV---", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P53541-1", "uniprot_id": "SPO1_YEAST", "id": "P53541-1", "name": "Putative meiotic phospholipase SPO1", "aln": "------MQKLLFVFSVLLTVVLATAPFQVQCPSSPLIREAKHELCPEETLYLKKKKIKTKNKLIQFLKSLTEAKFSSKFYKRVLKDPPKIGIAISGGGYRSMLVGTGFISQMNDYGLFEYSDYIAGLSGGSWILMDLVVQNFEVKSLLQEWDLEEDLLLGIPEFDISEEEIVTNAKKEYNDN--------------DLKMKKRQGGSLITSSSNFYEQIEEIMNSIEEIPEDYMITKRNLNPLARLKKIFFPNNTFTGTDAKIETFKKVLDFYKSLHLKIKPKKMEGFQISFTDYWGKAIVQRLKKNFDDDPNHSFSFSKLVNSSKKFKECSVPIPIFVANCKNG-----LLSNVIFEFTPFEFGSWENILRLFVKLPYLGSKIVSG---KAEKCINNFDDLGFITATSSSIFNNVLIFIWNLASQSSREAMKALNMVMGIFGLGKEEIFSISKDSSRLETDYAVYQPNPFYLYPEKDNVLTNKNHLYLVDGGEDGENIPLRTLVIPERELDVIFVLDSSSDIDN-YPNGSKLKRIFEKLDEE---NVHYQFPNNVKTFTHP------IVIGCNATKRTGHDSFLPIIIYHANANHGNASNTSTFKITYNQSEVSSMLPTGRGVFSNDYD-------LYYKNCLGCILTKRTMDRLPRKKKFSPFCLQCFKDYCYS------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : : .. . .. : . : .. .*. . . : . : : : : . : . . .. : . . : *. . :::* :. : : . : .. *:*: .. : .**.*:*:* * :*::. * : : . *. .: : :**.. : . . . . :. : * . . . . : * . . . : . : . : * :: . : *: . . :: . . * : : . .. : : : ", "identical_positions": 21, "similar_positions": 110, "identity": "2.62%" }, { "cls_id": "homologset.agr.MGI:1195260", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q04646-1", "uniprot_id": "ATNG_MOUSE", "id": "Q04646-1", "name": "Sodium/potassium-transporting ATPase subunit gamma", "aln": "MAGEISDLSANSGGSAKGTENPFEYDYETVRKGGLIFAGLAFVVGLLIILSKRFRCGGGKKHRQVNEDEL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q04679-1", "uniprot_id": "ATNG_RAT", "id": "Q04679-1", "name": "Sodium/potassium-transporting ATPase subunit gamma", "aln": "----MTELSANHGGSAKGTENPFEYDYETVRKGGLIFAGLAFVVGLLILLSKRFRCGGSKKHRQVNEDEL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P54710-1", "uniprot_id": "ATNG_HUMAN", "id": "P54710-1", "name": "Sodium/potassium-transporting ATPase subunit gamma", "aln": "----MTGLSMDGGGSPKGDVDPFYYDYETVRNGGLIFAGLAFIVGLLILLSRRFRCGGNKKRRQINEDEP", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: ** : ***.** :** *******:**********:*****:**:******.**:**:**** ", "identical_positions": 47, "similar_positions": 12, "identity": "67.14%" }, { "cls_id": "homologset.agr.MGI:1195261", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P70531-1", "uniprot_id": "EF2K_RAT", "id": "P70531-1", "name": "Eukaryotic elongation factor 2 kinase", "aln": "MADEDLIFRLEGVDGGGSSGAG-----------RHGDSDTDSDDDEGYFICPITDDHMS--------------NQNVN-SKGQGYYNNLLKTECG-STGSPASSFHFKEAWKHAIEKAKHMPDPWAEFHLEDIATEHATRHRYNAVTGEWLKDEVLIKMASQPFGRGAMRECFRTKKLSNFLHAQHWKGASNYVAKRYLEPVDRSVYFEDVQLQMEAKLWGEEYNRHKPPKQVDIMQMCIIELKDRQGQPLFHLEHYIEGKYIKYNSNSGFVRDDNIRLTPQAFSHFTFERSGHQLIVVDIQGVGDLYTDPQIHTEKGTDFGDGNLGVRGMALFFYSHACNRICQSMGLAPFDLSPREQDAVNQSTKLLQSAKTILRGTEEKCGSPRIRTLS-GSRPPLLLRLSENSGDENMSDVTFDSLPSSPSSATPHSQKLDHLHWPVFGDLDNMGPRDHDRMDNHRDSENSGDSGYPSEKRSDLDDPEPREHGHSNGNRRP-ESDEDSLGSSGRVCVETWNLLNPSRLHLPRPSAVALEVQRLNALDLGRKIGKSVLGKVHLAMVRYHEGGRFCEKDEEWDQESAIFHLEHAADLGELEAIVGLGLMYSQLPHHILADVSLEETEENKTKGFDYLLKAAEAGDRQSMILVARAFDTGLNLSPDRCQDWSEALHWYNTALETTDCDEGGEYDGIQDEPQYALLAREAEMLLTGGFGLDKNPQRSGDLYTQAAEAAMEAMKGRLANQYYEKAEEAWAQMEE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O08796-1", "uniprot_id": "EF2K_MOUSE", "id": "O08796-1", "name": "Eukaryotic elongation factor 2 kinase", "aln": "MADEDLIFCLEGVDGGRCSRAG-----------HNADSDTDSDDDEGYFICPITDDHMS--------------NQNVS-SKVQSYYSNLTKTECG-STGSPASSFHFKEAWKHAIEKAKHMPDPWAEFHLEDIATEHATRHRYNAVTGEWLKDEVLIKMASQPFGRGAMRECFRTKKLSNFLHAQQWKGASNYVAKRYIEPVDRSVYFEDVQLQMEAKLWGEDYNRHKPPKQVDIMQMCIIELKDRPGQPLFHLEHYIEGKYIKYNSNSGFVRDDNIRLTPQAFSHFTFERSGHQLIVVDIQGVGDLYTDPQIHTEKGTDFGDGNLGVRGMALFFYSHACNRICQSMGLTPFDLSPREQDAVNQSTRLLQSAKTILRGTEEKCGSPRIRTLS-SSRPPLLLRLSENSGDENMSDVTFDSLPSSPSSATPHSQKLDHLHWPVFGDLDNMGPRDHDRMDNHRDSENSGDSGYPSEKRSDLDDPEPREHGHSNGNRRH-ESDEDSLGSSGRVCVETWNLLNPSRLHLPRPSAVALEVQRLNALDLGRKIGKSVLGKVHLAMVRYHEGGRFCEKDEEWDRESAIFHLEHAADLGELEAIVGLGLMYSQLPHHILADVSLKETEENKTKGFDYLLKAAEAGDRHSMILVARAFDTGLNLSPDRCQDWSEALHWYNTALETTDCDEGGEYDGIQDEPQYALLAREAEMLLTGGFGLDKNPQRSGDLYTQAAEAAMEAMKGRLANQYYEKAEEAWAQMEE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00418-1", "uniprot_id": "EF2K_HUMAN", "id": "O00418-1", "name": "Eukaryotic elongation factor 2 kinase", "aln": "MADEDLIFRLEGVDGGQSPRAG-----------HDGDSDGDSDDEEGYFICPITDDPSS--------------NQNVN-SKVNKYYSNLTKSERYSSSGSPANSFHFKEAWKHAIQKAKHMPDPWAEFHLEDIATERATRHRYNAVTGEWLDDEVLIKMASQPFGRGAMRECFRTKKLSNFLHAQQWKGASNYVAKRYIEPVDRDVYFEDVRLQMEAKLWGEEYNRHKPPKQVDIMQMCIIELKDRPGKPLFHLEHYIEGKYIKYNSNSGFVRDDNIRLTPQAFSHFTFERSGHQLIVVDIQGVGDLYTDPQIHTETGTDFGDGNLGVRGMALFFYSHACNRICESMGLAPFDLSPRERDAVNQNTKLLQSAKTILRGTEEKCGSPQVRTLS-GSRPPLLRPLSENSGDENMSDVTFDSLPSSPSSATPHSQKLDHLHWPVFSDLDNMASRDHDHLDNHRESENSGDSGYPSEKRGELDDPEPREHGHSYSNRKY-ESDEDSLGSSGRVCVEKWNLLNSSRLHLPRASAVALEVQRLNALDLEKKIGKSILGKVHLAMVRYHEGGRFCEKGEEWDQESAVFHLEHAANLGELEAIVGLGLMYSQLPHHILADVSLKETEENKTKGFDYLLKAAEAGDRQSMILVARAFDSGQNLSPDRCQDWLEALHWYNTALEMTDCDEGGEYDGMQDEPRYMMLAREAEMLFTGGYGLEKDPQRSGDLYTQAAEAAMEAMKGRLANQYYQKAEEAWAQMEE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F318-1", "uniprot_id": "E7F318_DANRE", "id": "E7F318-1", "name": "Eukaryotic elongation factor 2 kinase", "aln": "MAEEELMFSMEEVGSARDGSRNRCVKNRVCFQNSNASDDDDEEDEDDLRICPITDDIISPTKGFCEFPKNLAHNQQLSNSLPKNSFTYKNKNDNIEDVRFGSLTEKGRATWKHAIEKAKAMPDPWAEFHLEEMETERCTRYRYSAITGEWAKDEIFIKVSSQTFGKGAMRECFRAKKLSNFSHSHNWKSASNYVAKRYMETVDRSVYFEDVRLQMEAKLWGEEFNRHRPPKQVDIMQMCVVEMTTRPGSPLFHLEHYIEGKYTKYNSNSGFVRDDNIRLTPQAFSHFTFERSGHQLIVVDIQGVGDLYTDPQIHTSKGTDFGDGNLGVRGMALFFHSHLCNKICRSMGLTRFDLSPAEIAQLDCTNKLLQSAKTVLRGFEEQCGSPRVRTTSLGHMPVLLSRLSETSSVDESSDT--DSIPCSPLSMG-VSVGRSPMGWSFMNEMN---ETHRSQNTEQQDSENGGDSGYPSEKRSEGDPVEHHGQGRPIYNRHYSESDEDSVR---RLTEEKWSFYHSSRSHIHRPSCVAVEVERLNALLLEKKIGKSILGKVHLAMVRYHEAGRFCEKDEPWDQISAMYHLETAAMCGELEAIVALGQCYLQLPHHILPEIELEPSEENSQKGFRFLLQAAEAGDRPSMILVARAFDTGLKLPSDRAMDWTEAVHWYDSALKMTDYDEGGEFDGMQDEPRYLLLARLAEMYQEGGNNLDADPQRAGDLFTEAADAAMEAMKGRLANQYYMKAEEAWAMMEE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:*:*:* :* *... . ....* *.:*::. ******* * **::. * : :. *.: . : : : : :*****:*** ***********:: **:.**:**.*:**** .**::**::**.**:********:****** *:::**.*********:*.***.******:**********::***:***********::*:. * *.************* ****************************************************..******************:** **:**.****: ***** * :: ..:*******:*** **:****::** * . * ** ***.*. :: **. **:*.** * * . : *..:.::: .:.: ::::***.**********.: * * : :*:. **: ******: *: *.*.: :.** *: *.*.**:**:***** * :*****:*************.******.* **: **::*** ** *******.** * *******.::.*: :***. *** :**:******* **********:* :*..**. ** **:***::**: ** *****:**:****:* :*** *** ** .*: :***:***:*:**:*************** ******* ***", "identical_positions": 447, "similar_positions": 160, "identity": "59.36%" }, { "cls_id": "homologset.agr.MGI:1195262", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Y2E5-1", "uniprot_id": "MA2B2_HUMAN", "id": "Q9Y2E5-1", "name": "Epididymis-specific alpha-mannosidase", "aln": "MGQLCWLPLLAPLLLLRPPGVQSAGPIRAFVVPHSHMDVGWVYTVQESMRAYAANVYTSVVEELARGQQRRFIAVEQEFFRLWWDGVASDQQKYQVRQLLEEGRLEFVIGGQVMHDEAVTHLDDQILQLTEGHGFLYETFGIRPQFSWHVDPFGASATTPTLFALAGFNAHLGSRIDYDLKAAMQEARGLQFVWRGSPSLSERQEIFTHIMDQYSYCTPSHIPFSNRSGFYWNGVAVFPKPPQDGVYPNMSEPVTPANINLYAEALVANVKQRAAWFRTPHVLWPWGCDKQFFNASVQFANMDPLLDHINSHAAELGVSVQYATLGDYFRALHALNVTWRVRDHHDFLPYSTEPFQAWTGFYTSRSSLKGLARRASALLYAGESMFTRYLWPAPRGHLDPTWALQQLQQLRWAVSEVQHHDAITGTESPKVRDMYATHLASGMLGMRKLMASIVL------------DELQPQAPMAASSDAGPAGHFASVYNPLAWTVTTIVTLTVGFPGVRVTDEAGHPVPSQIQNSTETPSAYDLLILTTIPGLSYRHYNIRPTAG-AQEGTQEPAATVASTLQFGRRLRRRTSHAGRYLVPVANDCYIVLLDQDTNLMHSIWERQSNRTVRVTQEFLEYHVNGDVKQGPISDNYLFTPGKAAVPAWEAVEMEIVAGQLVTEIRQYFYRNMTAQNYTYAIRSRLTHVPQGHDGELLCHRIEQEYQAGPLELNREAVLRTSTNLNSQQVIYSDNNGYQMQRRPYVSYVNNSIARNYYPMVQSAFMEDGKSRLVLLSERAHGISSQGNGQVEVMLHRRLWNNFDWDLGYNLTLNDTSVVHPVLWLLLGSWSLTTALRQRSALALQHRPVVLFGD----LAGTAPKLPGPQQQEAVTLPPNLHLQILSIPGWRYSSNHTEHSQNLRKGHRGEAQADLRRVLLRLYHLYEVGEDPVLSQPVTVNLEAVLQALGSVVAVEERSLTGTWDLSMLHRWSWRTGPGRHRGDTTSPSRPPGGPIITVHPKEIRTFFIHFQQQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O54782-1", "uniprot_id": "MA2B2_MOUSE", "id": "O54782-1", "name": "Epididymis-specific alpha-mannosidase", "aln": "MGPLRWLPLLGQLLLLWPRAAQPAGPIRAFVVPHSHMDVGWVFTVQESMRAYAANVYTTVVAELVRGGQRRFIAVEQEFFRLWWDGVASEQQKQQVRQLLHEGRLEFVLGGQVMHDEAVTHLDDQILQLTEGHGFLYETFGIRPQFSWHVDPFGASATTPTLFALAGFNAHLISRIDYDLKDAMQEAQMLQFVWHGSPSLSGQQEIFTHVMDHYSYCTPSHIPFSNRSGFYWNGVAVFPEPPPDGVYPNMSEPVTGANIHLYAEALVANVKQRAAWFRTPHVLWPWGCDKQFFNASVQFDNMDPLLDYINQRTAQFGISVQYATLNDYFQALHATNMTWGIRDHQDFLPYSSEPLQAWTGFYTSRSTLKGLARQASALLYAGESMFTRYMWPDPSGTLDPTWALQQLQQLRWAVSEVQHHDAITGTESPKVKNMYTEHLRMGMLGVRKLMVSIALGGPPGSGTGAPKDIMGPQVTPVLSVDTRPVGYSASVYNPLAWKITTIITLTVAFPNVSVTDELGHPVSTQIQNSTKDPSAYDLLILTTIPGLNYRHYQVMHARG-DQAGTRELVAPRANTLKFSLKLRNQPSQEGKRLVPVMNDCYILLFDQDTNMLHSIQDRQSNRTVRMTQEFLEYQANWDVKQGPISDNYLFAPNNTAEPSWEAVGMEMVAGTLVTDIRQYFYRYITDQEYIYSIHTRLAHP--SLAGELLCQRIEQQYRVGPLDLNREAILRTSSDLNSQQVLYSDNNGYQMQRRPYKAFKSNPIPRNYYPMVQSAFIEDDKSRLVLLAERPHGVSSQGNGQVEVMLHRRLWNNLAWDLKYNLTLNDTSIVHPVLWLMLGPKSTMTALHPRSGVALQHGPVVLLKE----LADEETPVHGPHNPWPVTLPPNLHLQILSVPGWTYSRSHAQHLRNLQRGHPEKPQANLQRVLLRLRHLYEAGEDPVLSRPATVDLKVVLRGLGSVVAVEERSLTGTWDVQMLQRWHWSTKTDHLKGHPTSPPRPPGGSIITVYPKEIRTFFIKFQQ-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M1PZ41-1", "uniprot_id": "A0A8M1PZ41_DANRE", "id": "A0A8M1PZ41-1", "name": "Alpha-mannosidase", "aln": "----MIFPFFFGLLLMTVSENDAAEKIQAFVIPHSHMDVGWVYTVQESMHAYASNVYSTVVEELTRVKNRKFIAVEQEFFRLWWTNVASDWHKKQVRQLLLEGRLEFIIGGQVMHDEAVTDVDDAILQLTEGHGFLYETFGVRPRFAWHVDPFGASATTPVLFALAGFDAHLISRIDYDLKDDMQKNKKLQFVWRGSPTLKEKQEIFTHTMDQFSYCTPSYIPFSNRSGFYWNGVALFPDPPKDGKYPNMSLPVTKETVELYAQTMVDNIRLRAQWFRSSHVLWPWGCDKQFYNASVQFSNMDVLMNYINTHSDQYGVTVQYATLKDYFQTLHQTNLSWDVRGNQDFLPYSTEPFQAWTGFYGSRNVLKGVARRASSLLYASESLFTRYHISYPDGPVQREWALSKLKALRWAVSEVQHHDGITGTESPKVADMYMEHLLQGMMGAEELLAAIFLLPQTLSN--DIYDQIKNTPTTARTDSENVPEQHIFVYNPLAWNISTYVNVSVQYAMAVVLDDDGKAVPAQIQPSMESSTVYDLFFVVELGGLQYRKYTVQFPQSPCDTGSACGATHVAKVVKFNKTNVRQWKKTGRKLLPVLNECYKLMFDQETNLLHSITDRSKKIRVRVQQDFWEYKANGDVQSGPISDNYIFTANGSAVPAYKSVVMEIVPGKVISEIRQYFYREEEDANHTYSVVTRVPVG---FKGRLSCFRLEQSYKVGPLEVNRETVFRTRTSLQNNRTLFTDNNGYQMMKRTYKGYANNTVARNYYPMVRVAYMEDESSRVVFLSERAHGVASLSQGQLEVMLHRRLWNNQEWNQGYNLTLNDSSVVRPVLWMMLGSPDSLSSIYQQEAVELQHRPVVMAIDQPQKLLNQRETFSGP-SVHPVVLPQNLHMQSLSIPGWNYSPEHSS-------GGDEKSEVNFDRILLRITHLYEEGESPVLSQPTTINLKEVMQGIGKVSKVQECSLTGTWNISDLQRWNWKTDETMQKTDKSGFSGVTQDFNVTISPKEIRTFFIYF---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q5M820-1", "uniprot_id": "MOFA1_RAT", "id": "Q5M820-1", "name": "MORF4 family-associated protein 1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRPLDAVELAEPEEVEVLE--------------PEEDFEQFLLPVIHEMREDIASLTRERGRAP-------VRNRGKLWEMDNMLIQIKTQVEASEESALNH---------LQGAGGAEPRGPRAEKADEKAQEMAKMAEMLVQLVRRIEKSESS-------------------------", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ..: * . * : * . * :* .:.. . :: :: .:*::: * .*...*.: ::. * . : .. . . : : : . : . ", "identical_positions": 10, "similar_positions": 43, "identity": "0.97%" }, { "cls_id": "homologset.agr.MGI:1195263", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P48059-1", "uniprot_id": "LIMS1_HUMAN", "id": "P48059-1", "name": "LIM and senescent cell antigen-like-containing domain protein 1", "aln": "--------------------------------------------------------------MANALASATCERCKGGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGKELTADARELKG----------ELYCLPCHDKMGVPICGACRRPIEGRVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLFGDVCFHCNRVIEGDVVSALNKAWCVNCFACSTCNTKLTLKNKFVEFDMKPVCKKCYEKFPLELKKRLKKLAETLGRK-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q99JW4-1", "uniprot_id": "LIMS1_MOUSE", "id": "Q99JW4-1", "name": "LIM and senescent cell antigen-like-containing domain protein 1", "aln": "--------------------------------------------------------------MANALASATCERCKGGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGKELTADARELKG----------ELYCLPCHDKMGVPICGACRRPIEGRVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLFGDVCFHCNRVIEGDVVSALNKAWCVSCFACSTCNTKLTLKNKFVEFDMKPVCKKCYEKFPLELKKRLKKLSETLGRK-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6A6W3-1", "uniprot_id": "A0A8I6A6W3_RAT", "id": "A0A8I6A6W3-1", "name": "LIM and senescent cell antigen-like-containing domain protein", "aln": "MAFPGRARPSTIPENEEIPQTALNSVLEANGNEDERAVSNLQRRHSDIKVYKEFCDFYAKFNMANALASATCERCKGGFDPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGKELTADARELKG----------ELYCLPCHDKMGVPICGACRRPIEGRVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLFGDVCFHCNRVIEGDVVSALNKAWCVSCFACSTCNTKLTLKDKFVAIDLKPVCKYCYEKMPEELKRRLARREREARDKEKQRKRKPVCL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M9QLM6-1", "uniprot_id": "A0A8M9QLM6_DANRE", "id": "A0A8M9QLM6-1", "name": "LIM domain-containing protein", "aln": "----------------------MLGVSEMTG-----------------------------SNMANALANASCERCKSGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFIIGRVIKAMNNSWHPDCFCCDICQAVLADVGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAIIEEQPLIFKNDPYHPDHFNCSNCGKELTADARELKG----------ELYCLPCHDKMGVPICGACRRPIEGRVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLFGDVCYHCNRVIEGDVVSALNKAWCVNCFSCSTCNTKLTLKDRFVEVDLKPVCKHCYERLPEELKRRLAKRERDSRERRK--KAIAVCL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8INQ9-1", "uniprot_id": "Q8INQ9_DROME", "id": "Q8INQ9-1", "name": "LIM domain-containing protein", "aln": "---------------------MMYSKAEVVQ----------------------------AANMS--LGAMHCTRCADGFEPTEKIVNSNGELWHTQCFVCAQCFRPFQDGIFYEFEGRKYCERDFHVLFAPCCNKCGEFVIGRVIKAMSASWHPQCFRCQLCAKELADCGFIKNQNRALCHECNAKVKAEITGRYVCQKCHGLIDEEPLRFRGEVYHGYHFSCTACGTELDSTAREVKSRPGLAANDMNELYCLRCHDKMGIPICGACRRPIEERVVTALGKHWHVEHFVCAKCEKPFLGHRHYEKRGLAYCETHYHQLFGNLCFVCNQVIGGDVFTALNKAWCVHHFACSVCDTKMTQKSKFYEYDEKPVCKKCYDRFPNELRRRLRTAHEMTMKKNT---------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: *. * ** .** *:**********:* *********: * :*:***********:**::******::****:********. ****:** *::* *** **:** .* **: *: : **. *:*:*****.:*:*:** *:.: ** **.*: **.** : ***:*. ***** ******:*********** ***.*:**:**********************::*********:****::*: **:** ***.:******** *:**.*:**:* *.:* * ***** **:::* **::** . : ", "identical_positions": 208, "similar_positions": 65, "identity": "50.98%" }, { "cls_id": "homologset.agr.MGI:1195264", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q91WV7-1", "uniprot_id": "SLC31_MOUSE", "id": "Q91WV7-1", "name": "Amino acid transporter heavy chain SLC3A1", "aln": "MDEDKGK-RDPIQMSLKGCRTNNGFVQNEDIPEQDPDPG-SRDTPQPNAVSIPAPEEPHLKAVRPYAGMPKEVLFQFSGQARYRVPREILFWLTVVSVFLLIGATIAIIVIS-------PKCLDWWQAGPIYQIYPRSFKDSDKDGNGDLKGIQEKLDYITALNIKTLWITSFYKSSLKDFRYAVEDFKEIDPIFGTMKDFENLVAAIHDKGLKLIIDFIPNHTSDKHPWFQSSRT-RSGKYTDYYIWHNC--THVNGVTTPPNNWLSVYGNSSWHFDEVRKQCYFHQFLKEQPDLNFRNPAVQEEIKE-IITFWLSKGVDGFSFDAVKFLLEAKD-----LRNEIQVNTSQIPDTVTHYSELYHDFTTTQVGMHDIVRDFRQTMNQYSREP--GRYRFMGAEAS-AESIERTMMYYGLPF-IQEADFPFNKYFTTI-GTLSG---------HTVYEVITSWMENMP-EGKWPNWMTGGPETPRLTSRVGSEY-------VNAMHMLLFTLPGTPITYYGEEIGMGDIS-----------------VTNFNES---YDSTT--------LVS--KSPMQWD-NSSNAGFTEANH-TWLPTNSDYHT-VNVDVQKTQPSSALRLYQDLSLLHATE---LVLSRGWFCLLRDDSHSVVYTRELDGIDNVFLVVLNFGESSTVLNLQGIISDLPPELRIRLSTNSASKGSAVDTRAISLEKGEGLVLEHSTKAPLHQQAAFRDRCFVSSRACYSSALDILYSSC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q64319-1", "uniprot_id": "SLC31_RAT", "id": "Q64319-1", "name": "Amino acid transporter heavy chain SLC3A1", "aln": "MNEDKDK-RDSIQMSMKGCRTNNGFVQNEDIQEQDPD---SRDTPQSNAVSIPAPEEPQLKVVRPYAGMPKEVLFQFSGQARYRVPREILFWLTVVSVFLLIGATIAIIIIS-------PKCLDWWQAGPMYQIYPRSFKDSDKDGNGDLKGIQEKLDYITALNIKTIWITSFYKSPLKDFRYAVEDFKEIDPIFGTMKDFENLVAAVHDKGLKLIIDFIPNHTSDKHPWFQSSRT-RSGKYTDYYIWHNC--THANGVTTPPNNWLSVYGNSSWQFDEERKQCYFHQFLKEQPDLNFRNPAVQEEIKE-IIKFWLSKGVDGFSFDAVKFLLEAKD-----LRNEIQVNTSQIPDTVTRYSELYHDFTTTQVGMHDLVRDFRQTMNQFSREP--GRYRFMGTEVS-AESTERTMVYYGLSF-IQEADFPFNKYLATL-DTLSG---------HTVYEAITSWMENMP-EGKWPNWMIGGPETSRLTSRVGSEY-------VNAMNMLLFTLPGTPITYYGEEIGMGDIS-----------------ITNLNER---YDTNA--------LLS--KSPMQWD-NSSNAGFTEANH-TWLPTNSDYHT-VNVDVQKTQPSSALRLYQDLSLLHARE---LLLSRGWFCLLRDDNHSVVYTRELDGIDKVFLVVLNFGESSTVLNLQETISDVPTKLRIRLSTNPASKGSDVDTHAVSLEKGEGLILEHSMKTLLHHQKAFRDKCFISNRACYSSVLDLLYSSC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q07837-1", "uniprot_id": "SLC31_HUMAN", "id": "Q07837-1", "name": "Amino acid transporter heavy chain SLC3A1", "aln": "MAEDKSK-RDSIEMSMKGCQTNNGFVHNEDILEQTPDPGSSTDNLKHSTRGILGSQEPDFKGVQPYAGMPKEVLFQFSGQARYRIPREILFWLTVASVLVLIAATIAIIALS-------PKCLDWWQEGPMYQIYPRSFKDSNKDGNGDLKGIQDKLDYITALNIKTVWITSFYKSSLKDFRYGVEDFREVDPIFGTMEDFENLVAAIHDKGLKLIIDFIPNHTSDKHIWFQLSRT-RTGKYTDYYIWHDC--THENGKTIPPNNWLSVYGNSSWHFDEVRNQCYFHQFMKEQPDLNFRNPDVQEEIKE-ILRFWLTKGVDGFSLDAVKFLLEAKH-----LRDEIQVNKTQIPDTVTQYSELYHDFTTTQVGMHDIVRSFRQTMDQYSTEP--GRYRFMGTEAY-AESIDRTVMYYGLPF-IQEADFPFNNYLSML-DTVSG---------NSVYEVITSWMENMP-EGKWPNWMIGGPDSSRLTSRLGNQY-------VNVMNMLLFTLPGTPITYYGEEIGMGNIV-----------------AANLNES---YDINT--------LRS--KSPMQWD-NSSNAGFSEASN-TWLPTNSDYHT-VNVDVQKTQPRSALKLYQDLSLLHANE---LLLNRGWFCHLRNDSHYVVYTRELDGIDRIFIVVLNFGES-TLLNLHNMISGLPAKMRIRLSTNSADKGSKVDTSGIFLDKGEGLIFEHNTKNLLHRQTAFRDRCFVSNRACYSSVLNILYTSC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QEA9-1", "uniprot_id": "F1QEA9_DANRE", "id": "F1QEA9-1", "name": "Amino acid transporter heavy chain SLC3A1", "aln": "MSLTRVTNIDAVELQEG--------IQNAAFREDDDD---NNGDIVCIRRVSSLPEESEYTQIKPYAGMPKEVLMLYSNKPCYRIPREVIFWLVIACTLALIAMTAAIVALS-------PRCMSWWQLSPIYQVYPRSFKDSNADGVGDLRGIKEKLSHFEYLNIKAIWISPFYKSPMRDFGYDVEDFRDVDPLFGTMEDFDDLLTSMHDKGLKLIMDYIPNHTSDKHVWFQLSRN-YTEPYTDYYIWVNC--TADK----HPNNWVSVFGNSTWEYDEIRQQCYFHQFLKEQPDLNYRNPLVLQEMTD-IIHFWLKKGVDGFRMDAVKHMLEATH-----LRDEPQVNPDQDPSTVDTEFELYHDYTYTQAGLHEILTDWRIQMDTYSREP--GRYRFMVMESYDYEEIDKTMRYYGTNY-AKESDFPFNFYLLDLPDNLSG---------NYAKSIVERWMSNMP-KGKWPNWVVGNHDKPRIGSSAGKEY-------VRALNMLLLTLPGTPTTYYGEEIGMVDVN-----------------ISVIQDPAGQYDPSK--------SRDPQRTPMQWN-NELNAGFSESLNGTWLDIASDYRT-VNVEVQQDDTSSTISQYRALSLLRSSN---VILSRGWFCYVWNDVNVFAYLRELDGLSKGFLVVLNFGKE-TTTDLS-SVKELPDSLTLHLSTESITQ-TEFPKSRIPTSQGQGLLLEYSSSQKFHLN--HQSQCYVSEKACYLPALDILYQC-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z7F2-1", "uniprot_id": "A1Z7F2_DROME", "id": "A1Z7F2-1", "name": "alpha-glucosidase", "aln": "----------------------------------------------------------------------------------MQGTRLDHFGLLVCGLVILAHPSWSCET-----TTSTTVTKDWWENAQFYQIYPRSFMDSDGDGIGDLNGITSKLEYLKDLGVTAAWLSPIFTSPMVDFGYDISDFFDIQPEYGTLDDFRALIKRANELDLKIILDFVPNHSSDENSWFVKSVN-REKGYEDYYVWHDGRVNATTGGREPPSNWLQAFRGSAWEWNEKRQQYYLHQFAVQQADLNYRNPLVVEQMKR-VLRYWLDLGVAGFRCDAVPVLFEIEPDADGQYADEELSGLTD---DVDDRKYLKSDLIENRPETIDMAYQWRVVMDDYQRIH-GGETRVLLIETY--APPAYTMQFYGNRS-TAGAHLPFNFNLITVLASD-------GVSAGSIKTAVDNWLDNLP-AGRTANWVIGNHDQRRAASRYGTAN-------ADAMNMLVMVLPGASVTYQGEELGMTDG------------------EISWEDTQDPAACNSNSDIYEQFTRDPSRTPFQWT-NGTNAGFSTASK-TWLPLAADYQT-LNVETEAAAQRSHLKIYKALVELRKSS---LPLQNGSTKYGVVGENVFVVKRYISGSA-SIIYVANFASKGVTVDLYEFDKTLPTHLTLLIRSLQSSKAEGS------QFEVTGLSLAAGEALVLSSSSSSRFD--------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A1Z7F3-1", "uniprot_id": "A1Z7F3_DROME", "id": "A1Z7F3-1", "name": "alpha-glucosidase", "aln": "---------------------------------------------------------------------------------------MELLSLLTLLLLAIASNEACQVQ-----SSSSETTKDWWQTAQFYQIYPRSFKDSDGDGIGDLNGITSKLEYLKDLGVTAAWLSPIFKSPMVDFGYDISDFFDIQPEYGTLEDFRTLIKRAKELDLKIVLDFVPNHSSNESEWFLKSVK-REKGYEDYYVWHDGKVNSTTGKREPPTNWLQYFRGSAWEWNEVRQQYYLHQFAVQQPDLNYRNPLVVEQMKR-VLRYWLNEGVSGFRCDALPPLFEVVPDSDGQFPDEVVSGATE---DKEDRDYLTTTYIENQPETIDMVYQWRTVLDDHKRIF-GGNSSVLLIETY--SPAWFTMQFYGNRS-TEGAHLPFNFNLITVMEQS-------GLSASNVQEAIDLWLKNMP-AGRTPNWVLGNHDKRRAASRYGKEN-------IDGMNMLVMILPGVSVTYQGEEIGMTDG------------------EISWEDTVDPWGCNSNPNIYEQYTRDPERTPFQWT-GGTNAGFTNGSS-TWLPLAADYAT-INVEKELSDDHSHLKIYKALVALRKSS---KTLQNGSTKYQALSEDIFVVQRSLTKSA-TIVLVINFGSVAKTVDLSQFDKSRTESLQLLIRSIDSTKKEGT------RYDPKALSLDPSEALVLTTE--------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A1Z7F1-1", "uniprot_id": "A1Z7F1_DROME", "id": "A1Z7F1-1", "name": "alpha-glucosidase", "aln": "----------------------------------------------------------------------------------MACFKVLIAAILVLGIHCALGSAAAVDLDLERATTAADTTRDWWQVAQFYQIYPRSYKDSDGDGIGDLQGIISKLDYLKEIGVTATWLSPIYSSPMADFGYDISDFFDIQPEYGTLADFDELIAEAKKRNIKIILDFVPNHSSDENVWFQKSVK-REKGYEDYYMWHDGYVNATTGKREPPSNWLQAFRGSAWEWNDERQQYYLHQFAVKQPDLNYRNPAVVAQMKR-VLTYWLDRGVAGFRMDAVPWCFEVLPDADGRYPDEPLSGYTD---DPDDSSYLKHIYTQDLRETVEMVFQWRTLLDDYQRIH-GGDTRVIMVETY--SGLDYVMQFYGNRT-TKGAQMPFNFQFIIGGNGDKNNT---QLNATGFVKIISSWLSQMP-AGQTANWVMGNHDQRRVGSRYGENR-------IDLMNMLQMFLPGVSITYQGEELGMTDL------------------DISWEDSRDPAACNSNSDIYEQFTRDPARTPFQWS-DEANAGFSTNAT-TWLPINPNYVT-VNAKAENSTSPSHLSLYKQLVDLRKS----KTLQFGATRYANVGDNVVAIRRYLSGEP-SYVLVANVLDTSVSGIDVASAIYATGSYKIKLLNPQAKATVGD------SVTLSNLTLEPYAALILESV--------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P07190-1", "uniprot_id": "MAL1_DROME", "id": "P07190-1", "name": "Maltase A1", "aln": "-------------------------------------------------------------------------------------MRPQSAACLLLAIVGFVG------------------ATEWWESGNYYQIYPRSFRDSDGDGIGDLNGVTEKLQYLKDIGFTGTWLSPIFKSPMVDFGYDISDFYQIHPEYGTMEDFERMIAKAKEVGIKIILDFVPNHSSTENEWFTKSVD-SDPVYKDFYIWHDGKINNETGEREPPSNWNSEFRYSAWEWNEVRQQYYLHQFAIQQADLNYRNPAVVNEMKN-VIRFWLGKGVSGFRIDAVPYLFEVDLDRYNQYPDEPLTNDSVNCPDPDDHCYTQHIYTQDMPETIDMVYQWRELVDEFHVEN-GGDKRLLMTEAY--TSFENIMTYYGNGV-RNGSHIPFNFDFLTSINNAS--------KAGEYVEHIKKWMDAMP-EGVYANWVLGNHDNKRVASRFGVQR-------TDLINILLQTLPGHAVTYNGEELGMTDV------------------WISWEDTVDPNACNSDPDNYYARSRDPARSPYQWD-ASSKAGFTSADH-TWLPVADDYKT-NNALQQLRAPRSHLQIFKKLVRVRKE----PSFRQGELNIQAIDDDVIIYSRQKTGSD-LYVIVLNLGSTSKTLDLTKYYELG-TQAEVITTSLSSQYIDGD------VIKSTEFVANPYVGTVLVAV--------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P07192-1", "uniprot_id": "MAL3_DROME", "id": "P07192-1", "name": "Maltase A3", "aln": "-----------------------------------------------------------------------------------MFKLLVLSCLLALALPSLAEVG-------------------WWKTGQFYQIYPRSFKDSDGDGVGDLIGITQQLPYLKEIGITATWLSPIFTSPMADFGYDVADLKGIDPIFGTMEDFEALLARAKELDIKIILDFVPNHTSDECDWFIRSAA-GEEEYKDFYVWHTGKVVN--GIRQPPTNWVSVFRGSMWTWNEQRQAYYLHQFHAKQPDLNYRNPKVVEAMKD-VLRFWLRKGAYGFRIDAVPHVYEIPADADGNWPDEPRNEAVS---DPEDYTYLQHIYTTDQPETLELVYAFRDVIEEIDAEL-GGDDRVLLTEAY--SPLEVLMQYYGNGT-HLGSQIPFNFELLAKISYSS--------DAYHYSELIHNWLDNMP-EGQVANWVFGNHDQSRIGSRLGADR-------IDACNMIILGLPGVSVTYQGEEMGMTDV------------------WISWEDTVDPQACQSNEQEFERLTRDPVRTPFQWS-DEVNAGFSNASV-TWLPVASNYKL-VNVKKERGIALSHLNVYKQLRALRDE----PTLKQGDVSVTAIGPNVLAFKRSLAGYK-SYITLININDDVESINLDSVFTSITTQLQYVVVNDKSVRRKND------LTFANSVLLLPKEAVVLSTV--------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A1Z7E8-1", "uniprot_id": "A1Z7E8_DROME", "id": "A1Z7E8-1", "name": "alpha-glucosidase", "aln": "-----------------------------------------------------------------------------------MTTWTSLFLLLGLGLLAVDAAAP------------------WWKTASFYQIYPRSFKDSDGNGVGDLNGVTEKLEYLKEIGVTATWLSPFLKSPMADFGYDISDFKAVDPLFGTMEDFENMVSRAKELGVKIILDFVPNHSSDECDWFLRSAA-GEEEYKDYYMWHPGFLDED-GTRRPPTNWVSVFRGSAWEWHEGRQEYYLHQFHKKQPDFNFRNPVVREEMNN-VLRFWLEKGVDGFRVDAIYHAFEIEADENGNYPDEPRNDWTN---DPDEYGYTHKIYTVDQPETPHLVYEWRQILEQFQADN-GGDERILMVETW--SPIEIVMHYYGNET-ADGAQIPFNFQLISNLHYDS--------DAYHYEYLINNWLNLMP-EGKSANWVIGNHDKNRVGSRFGADR-------VDLFNILLLTLPGCSITYQGEELGMLDG------------------YVSWEDTVDPQACNGYEANYMDNSRDPARTPMHWS-DETMAGFTTGNS-TWLPVSTDYRQ-RNVKTERGVSLSHLNVFKRLQQLRQE----PSIEEGSAEVKAVSNYVLAVKRHLSGDF-VYISLFNIFDSIENVNLSSVFGSLPAKFQYALVTEKSIKKVGD------QVSAGSVTLMPHESIVLRSTTTA-----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P07191-1", "uniprot_id": "MAL2_DROME", "id": "P07191-1", "name": "Maltase A2", "aln": "-----------------------------------------------------------------------------------MPKWAHLGLAALLLISTTQEGTAD---------------IDWWENASLYQIYPRSFQDSDGDGIGDLKGITSRLGYLKEIGITATWLSPIFTSPMSDFGYDISNFYDIDPIFGTLEDFDDLIVEAKSLGVKIILDFVPNHSSDENVWFEKSVN-REDGYDDFYVWDDGKLNEETGARDPPSNWVSVFSGPMWTWNEKRQQYFLHQFQVKQPDLNFTNPMVREHMLD-VLKFWLDRGVDGFRIDAVPHIYEHRN-ADGSYPDEPVSGWGS---DPNAYDYHDHIYTKDQPATVDLMYEWREFLDNYRAQN-GGDSRVLLAEAY--SSVETLSAYFGNST-HQGTQLPMNFQLMYLSGYS---------TAKDVVGSIDYWMNTMWKEHQTANWVVGNHDTNRVADRMGAHK-------VDLLNVIVNALPGASVTYYGEEIGMSNV------------------DVECTG----DSCE---------DRDGERTPMQWT-AGKNADFSDGES-TWLPLSPEYQR-YNVQTERGVSRSSLNIFKGLQELKSSSAFLAFKEDGGFSYEAVTEQVLQIIRTNKISE-EYRILVNMGNGMEILD-----GLAPKTYEYVLATAYSTHYSGQK-----ADLSQRIILMPYEAVVLRWLA-------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VKE6-1", "uniprot_id": "Q9VKE6_DROME", "id": "Q9VKE6-1", "name": "alpha-glucosidase", "aln": "------------------------------------------------------------------------------------MVVVKIAFILSVGLVGILAHKHQSK--------ELDAKYNWWQHEVFYQIYPRSFQDSNGDGIGDLQGITSRLQYFKDTGITSVWLSPIYESPMVDFGYDISNYTNIQPEYGTLEDFDALIAKANELGVKVILDFVPNHSSNKHPWFIKSVA-REPGYEDFYVWEDG-ILLENGTRVPPNNWLSVFSGSAWMWNDERQQYYLRQFTYGQPDLNYRNPAVIKAMDD-VMLFWLNKGIAGFRIDAIIYIYEDAQ-----LRDEPPSGTTD---DPNNEAYLSHIYTRNQPEDYGLLQHWRQLLDNYTANH-DGPLRIMMTEGY--ASVSQLMEYYEDSNGVQGPQFPFNFDFITELNANS--------TAADFVFYISRWLIYMP-HGHVANWVMGNHDNPRVASRFGEKS-------VDAMNMLLMTLPGIGITYNGEELGMTDYR-----------------DISWSDTVDQPACEAGIDNYKTISRDPERTPMQWS-SDVNAGFSSADR-TWLPVNPNYKE-LNLRNQQQARRSHYKIYQSLLKLRQL----PVLKNGSFVPEVVNRRVFAFKRELKNEH-TLLTIVNVSNRTELVDIADFIEQP-NRLSVLVAGVDSQHRVGD------RLKAETIELAPNEGLVIQLNKRK-----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A4P1SA55-1", "uniprot_id": "A0A4P1SA55_DROME", "id": "A0A4P1SA55-1", "name": "alpha-glucosidase", "aln": "----------------------------------------------------------------------------------MRAPLIQILLFSLLNSGSIMAGLVKS---------DTEDFIDWWPHTVFYQIYPRSFKDSNGDGIGDLKGITSKLRYLADTGITATWLSPIFQSPMIDFGYDISDYKAIQPEYGTMQDFEELIDTAFELGIKVVLDFVPNHSSDQHEWFKKSAA-REPGYEDFYVWHDG-IVQENGTRVPPNNWPSVFYGSAWEWHEGREQYYLHQFTKEQPDLNYRNPKVVQAMDD-VLLFWLNKGVAGFRIDAVNHLFEDES-----LKDEPLSGKTT---DSLSYDYTKHIYSRDLPEVLEMIHHWRQLLDDFSAKHPERPTRIMMTEAY--AGLTQLADYYEDSNGVRGSHLPFNFHFITDVKGDS--------DARDYVYNVEKWLIYMP-RGHAANWVMGNHDNPRVASRFGPAS-------VDAMNMLLLTLPGVAVTYNGEELGMVDYR-----------------ELSWEETVDPPARNVGEKLYQEVSRDPVRTPFQWN-NETNAGFSTAAK-TWLPVHPNYLE-LNLEAQKVANRSHYQVYKDLLELRKS----AIMRVGRFNIEPLTRWVFAFKRSYPNFE-SIITVINVSDKEQLVDLSEFLSQP-KKLVVEVSGVDSKYQPGQ------SLAASALLLAAREGLVCRLV--------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P0CW41-1", "uniprot_id": "MALX4_YEAST", "id": "P0CW41-1", "name": "Oligo-1,6-glucosidase IMA4", "aln": "-------------------------------------------------------------------------------------------MTISSAHPE--------------------TEPKWWKEATIYQIYPASFKDSNNDGWGDMKGIASKLEYIKELGTDAIWISPFYDSPQDDMGYDIANYEKVWPTYGTNEDCFALIEKTHKLGMKFITDLVINHCSSEHEWFKESRSSKTNPKRDWFFWRPPKGYDAEGKPIPPNNWRSYFGGSAWTFDEKTQEFYLRLFCSTQPDLNWENEDCRKAIYESAVGYWLDHGVDGFRIDVGSLYSKVAG-----LPDAPVIDENS-------KWQLSDPFTMNGPRIHEFHQEMNKFIRNRVKDG-----REIMTVGEMRHATDETKRLYTSAS-RHELSELFNFSHTDVGTSPKFRQNLIPYELKDWKVALAELFRYVNGTDCWSTIYLENHDQPRSITRFGDDSPKNRVISGKLLSVLLVSLSGTLYVYQGQELGEINFKNWPIEKYEDVEVRNNYDAIKEEHGENSKEMKRFLEAIALISRDHARTPMQWSREEPNAGFSGPNAKPWFYLNESFREGINAEDESKDPNSVLNFWKEALRFRKAHKDITVYGYDFEFIDLDNKKLFSFTKKYDNKT--LFAALNFSSDSIDFTIPNNSSSFKLEFGNYPRSEVDAS---------------SRTLKPWEGRIYISE--------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P0CW40-1", "uniprot_id": "MALX2_YEAST", "id": "P0CW40-1", "name": "Oligo-1,6-glucosidase IMA3", "aln": "-------------------------------------------------------------------------------------------MTISSAHPE--------------------TEPKWWKEATIYQIYPASFKDSNNDGWGDMKGIASKLEYIKELGTDAIWISPFYDSPQDDMGYDIANYEKVWPTYGTNEDCFALIEKTHKLGMKFITDLVINHCSSEHEWFKESRSSKTNPKRDWFFWRPPKGYDAEGKPIPPNNWRSYFGGSAWTFDEKTQEFYLRLFCSTQPDLNWENEDCRKAIYESAVGYWLDHGVDGFRIDVGSLYSKVAG-----LPDAPVIDENS-------KWQLSDPFTMNGPRIHEFHQEMNKFIRNRVKDG-----REIMTVGEMRHATDETKRLYTSAS-RHELSELFNFSHTDVGTSPKFRQNLIPYELKDWKVALAELFRYVNGTDCWSTIYLENHDQPRSITRFGDDSPKNRVISGKLLSVLLVSLSGTLYVYQGQELGEINFKNWPIEKYEDVEVRNNYDAIKEEHGENSKEMKRFLEAIALISRDHARTPMQWSREEPNAGFSGPNAKPWFYLNESFREGINAEDESKDPNSVLNFWKEALRFRKAHKDITVYGYDFEFIDLDNKKLFSFTKKYDNKT--LFAALNFSSDSIDFTIPNNSSSFKLEFGNYPRSEVDAS---------------SRTLKPWEGRIYISE--------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q08295-1", "uniprot_id": "IMA2_YEAST", "id": "Q08295-1", "name": "Oligo-1,6-glucosidase IMA2", "aln": "-------------------------------------------------------------------------------------------MTISSAHPE--------------------TEPKWWKEATIYQIYPASFKDSNNDGWGDMKGIASKLEYIKELGADAIWISPFYDSPQDDMGYDIANYEKVWPTYGTNEDCFALIEKTHKLGMKFITDLVINHCSSEHEWFKESRSSKTNPKRDWFFWRPPKGYDAEGKPIPPNNWRSYFGGSAWTFDEKTQEFYLRLFCSTQPDLNWENEDCRKAIYESAVGYWLDHGVDGFRIDVGSLYSKVAG-----LPDAPVIDENS-------KWQPSDPFTMNGPRIHEFHQEMNKFIRNRVKDG-----REIMTVGEMQHATDETKRLYTSAS-RHELSELFNFSHTDVGTSPKFRQNLIPYELKDWKVALAELFRYVNGTDCWSTIYLENHDQPRSITRFGDDSPKNRVISGKLLSVLLVSLSGTLYVYQGQELGEINFKNWPIEKYEDVEVRNNYDAIKEEHGENSKEMKRFLEAIALISRDHARTPMQWSREEPNAGFSGPNAKPWFYLNESFREGINAEDESKDPNSVLNFWKEALRFRKAHKDITVYGYDFEFIDLDNKKLFSFTKKYDNKT--LFAALNFSSDSIDFTIPNNSSSFKLEFGNYPRSEVDAS---------------SRTLKPWEGRIYISE--------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P53051-1", "uniprot_id": "MALX3_YEAST", "id": "P53051-1", "name": "Oligo-1,6-glucosidase IMA1", "aln": "-------------------------------------------------------------------------------------------MTISSAHPE--------------------TEPKWWKEATFYQIYPASFKDSNDDGWGDMKGIASKLEYIKELGADAIWISPFYDSPQDDMGYDIANYEKVWPTYGTNEDCFALIEKTHKLGMKFITDLVINHCSSEHEWFKESRSSKTNPKRDWFFWRPPKGYDAEGKPIPPNNWKSYFGGSAWTFDEKTQEFYLRLFCSTQPDLNWENEDCRKAIYESAVGYWLDHGVDGFRIDVGSLYSKVVG-----LPDAPVVDKNS-------TWQSSDPYTLNGPRIHEFHQEMNQFIRNRVKDG-----REIMTVGEMQHASDETKRLYTSAS-RHELSELFNFSHTDVGTSPLFRYNLVPFELKDWKIALAELFRYINGTDCWSTIYLENHDQPRSITRFGDDSPKNRVISGKLLSVLLSALTGTLYVYQGQELGQINFKNWPVEKYEDVEIRNNYNAIKEEHGENSEEMKKFLEAIALISRDHARTPMQWSREEPNAGFSGPSAKPWFYLNDSFREGINVEDEIKDPNSVLNFWKEALKFRKAHKDITVYGYDFEFIDLDNKKLFSFTKKYNNKT--LFAALNFSSDATDFKIPNDDSSFKLEFGNYPKKEVDAS---------------SRTLKPWEGRIYISE--------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P38158-1", "uniprot_id": "MAL32_YEAST", "id": "P38158-1", "name": "Alpha-glucosidase MAL32", "aln": "-------------------------------------------------------------------------------------------MTIS-DHPE--------------------TEPKWWKEATIYQIYPASFKDSNNDGWGDLKGITSKLQYIKDLGVDAIWVCPFYDSPQQDMGYDISNYEKVWPTYGTNEDCFELIDKTHKLGMKFITDLVINHCSTEHEWFKESRSSKTNPKRDWFFWRPPKGYDAEGKPIPPNNWKSFFGGSAWTFDETTNEFYLRLFASRQVDLNWENEDCRRAIFESAVGFWLDHGVDGFRIDTAGLYSKRPG-----LPDSPIFDKTS-------KLQHPNWGSHNGPRIHEYHQELHRFMKNRVKDG-----REIMTVGEVAHGSDN--ALYTSAA-RYEVSEVFSFTHVELGTSPFFRYNIVPFTLKQWKEAIASNFLFINGTDSWATTYIENHDQARSITRFADDSPKYRKISGKLLTLLECSLTGTLYVYQGQEIGQINFKEWPIEKYEDVDVKNNYEIIKKSFGKNSKEMKDFFKGIALLSRDHSRTPMPWTKDKPNAGFTGPDVKPWFFLNESFEQGINVEQESRDDDSVLNFWKRALQARKKYKELMIYGYDFQFIDLDSDQIFSFTKEYEDKT--LFAALNFSGEEIEFSLPREGASLSFILGNY--DDTDVS---------------SRVLKPWEGRIYLVK--------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P53341-1", "uniprot_id": "MAL12_YEAST", "id": "P53341-1", "name": "Alpha-glucosidase MAL12", "aln": "-------------------------------------------------------------------------------------------MTIS-DHPE--------------------TEPKWWKEATIYQIYPASFKDSNNDGWGDLKGITSKLQYIKDLGVDAIWVCPFYDSPQQDMGYDISNYEKVWPTYGTNEDCFELIDKTHKLGMKFITDLVINHCSTEHEWFKESRSSKTNPKRDWFFWRPPKGYDAEGKPIPPNNWKSFFGGSAWTFDETTNEFYLRLFASRQVDLNWENEDCRRAIFESAVGFWLDHGVDGFRIDTAGLYSKRPG-----LPDSPIFDKTS-------KLQHPNWGSHNGPRIHEYHQELHRFMKNRVKDG-----REIMTVGEVAHGSDN--ALYTSAA-RYEVSEVFSFTHVEVGTSPFFRYNIVPFTLKQWKEAIASNFLFINGTDSWATTYIENHDQARSITRFADDSPKYRKISGKLLTLLECSLTGTLYVYQGQEIGQINFKEWPIEKYEDVDVKNNYEIIKKSFGKNSKEMKDFFKGIALLSRDHSRTPMPWTKDKPNAGFTGPDVKPWFLLNESFEQGINVEQESRDDDSVLNFWKRALQARKKYKELMIYGYDFQFIDLDSDQIFSFTKEYEDKT--LFAALNFSGEEIEFSLPREGASLSFILGNY--DDTDVS---------------SRVLKPWEGRIYLVK--------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P40884-1", "uniprot_id": "IMA5_YEAST", "id": "P40884-1", "name": "Oligo-1,6-glucosidase IMA5", "aln": "-------------------------------------------------------------------------------------------MTII-------------------------HNPKWWKEATVYQIYPASFKDSNNDGWGDLAGITSKLDYVKELGVDAIWVCPFYDSPQEDMGYDIANYEKVWPRYGTNEDCFQMIEEAHKRGIKVIVDLVINHCSEEHEWFKESRSSKANPKRDWFFWRPPKGYDEKGNPIPPNNWRSFFGGSAWRYDEKTGEFFLHVFALGQPDFNWENEECRKAIYDSSVGYWLRHNVDGFRIDVGSMYSKVEG-----LPDAPITDPTV-------PYQKGTEFFINGPRIHEYHKEMHNYMLSQVPEG-----KEIMTVGEVGIGNEDDFRVYTSAK-EGELNMMFNFKHTSVGENPKCKYELIPFTLKDFKLALAESFLFIENTDCWSTIYLENHDQPRSVSRFGSDSPKWREISSKMLATLIISLTGTVFIYQGQELGMPNFKNRKIEQIKCVEGTGTYAAIKRDYGEDSEKMKKFFEALALISRDHGRTPFPWSADEPSAGFS-KDAKPWIDMNESFRDGINAEAELKDKNSVFFFWKKALQVRKEHKDILVYGHNFQFIDLDNDKLFMFTKDTDNKK--MFAVFNFSSDNTDFSVPDNEASYTMFFGNY--ANSNGD---------------SRTLQPWEGRLYLLK--------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** **:** *: **: :* **: *: .:* :. . *: .: *. *: * : : : * :** * :: . .:*.: * : ** * : ** * *::.* *.** . : . * :.: ::: * * *:*: * : : :** . ** *. : : . : : : :. : : : .. . : * . : *.* * *:*:* : . ::* * *.*: .*: .: * : * :: : . . : *. ", "identical_positions": 61, "similar_positions": 87, "identity": "8.02%" }, { "cls_id": "homologset.agr.MGI:1195265", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z301-1", "uniprot_id": "PER2_RAT", "id": "Q9Z301-1", "name": "Period circadian protein homolog 2", "aln": "-----------------------------MNGYVDFSP----SPTSPTQEPGEPQPTQ--------AVLQEDVDMSS--GSSG----------NENCSTGRDSQGSDCDDSG----KELRMLVES-----SNTH----PSPDDTFRLMMTEAEH-NPSTSGCSSEQSAKADAHKELIRTLRELKVHLPADKKAKG-KASTLATLKYALRSVKQVKAN------------EEYYQLLMSSESQPCSVDVPSYTMEQVEGITSEYIVKNSDMFAVAVSLVSGKILYISNQVAPIFHCKKDAFSDAKFVEFLAPHDVSVFHSYTTP-YKLPPWSVSSGLDSFTQECMEEKSFFCRVSVGK-HHENEIRYQPFRMTPYLVKVQEQKGAA-------SQLCCLLLAERVHSGYEAPRIPPEKR--IFTTTHTPNCLFQDVDERAVPLLGYLPQDLIETPVLVQLHPSDRPLMLAIHKKILQ---ASGQPFDYSPIRFRTRNGEYITLDTSWSSFINPWSRKISFIIGRHKVRVGPLNEDVFAASPCPEEKTPHPSVQELTEQIHRLLMQPVPHSGSSGYGSLGSNGSHEHLMSQTSSSDSNG------QEESHWRRSGIFKTSGKSQSKSHFSPESGGQKEASVAEMQSSPPAQVRSVTTMERDSSGASLPKASFPEELTYKSQPPCSYQQISCLDSVIRYLESCNEAATLKRKCEFPANIPS------RKATVSPGLHSGEAARSSKVTS-------------HTEVSAHLSSLALPGKAESVVSLTSQCSYSSTIVHVGDKKPQPE--------------LETVEDVAS--GPESQDDAAG-----GLSQEKGSLQKLGLTKEVLAAHTQREEQGFLQRFREVSRLGALQAHCQNYLQERSRAPASDR---GLRNASG----IESSWKKTGKNRKLKSKRVKTRDSSESTGSGGPVSHRPPLVGLNATAWSPSDTSQSSCPSAPFPAPVP-AYPLPVFPAPGIVSTPGTVVAPPAAAHTGFTMPVVPMGTQPEFAVQPLPFAAPLA-PVMAFMLPSYPFPPATPNLPQAFFPS-QPHFPAHPTLASEITPASQAEFPSRTSMLRQ--------------------PCACPVTPPAG--------------TVALG---RASPPLFQSRGSSPLQLNLLQLEEAPESSTGAAGTLG---TTGTAASGLDCTSGASRDRQPKAPPTCSE--PSDTQNSDAISTSSDLLNLLLGEDLCSATGSALSRSGASATSDSLGSSSLGCDTSRSGAGSSDTS------HTSKYFGSIDSSENNHKAKMITD----TEESEQFIKYVLQDPIWLLMANTDDNIMMTYQLPSRDLQAVLKEDQEKLKLLQRSQPHFTEGQRRELREVHPWVHTGGLPTAIDVTGCVYCESE-------EKGNLCLPYEEDSPSLGLCDTSEAKEEESGQLANPRKEAQT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O54943-1", "uniprot_id": "PER2_MOUSE", "id": "O54943-1", "name": "Period circadian protein homolog 2", "aln": "-----------------------------MNGYVDFSP----SPTSPTKEPGAPQPTQ--------AVLQEDVDMSS--GSSG----------NENCSTGRDSQGSDCDDNG----KELRMLVES-----SNTH----PSPDDAFRLMMTEAEH-NPSTSGCSSEQSAKADAHKELIRTLKELKVHLPADKKAKG-KASTLATLKYALRSVKQVKAN------------EEYYQLLMSSESQPCSVDVPSYSMEQVEGITSEYIVKNADMFAVAVSLVSGKILYISNQVASIFHCKKDAFSDAKFVEFLAPHDVSVFHSYTTP-YKLPPWSVCSGLDSFTQECMEEKSFFCRVSVGK-HHENEIRYQPFRMTPYLVKVQEQQGAE-------SQLCCLLLAERVHSGYEAPRIPPEKR--IFTTTHTPNCLFQAVDERAVPLLGYLPQDLIETPVLVQLHPSDRPLMLAIHKKILQ---AGGQPFDYSPIRFRTRNGEYITLDTSWSSFINPWSRKISFIIGRHKVRVGPLNEDVFAAPPCPEEKTPHPSVQELTEQIHRLLMQPVPHSGSSGYGSLGSNGSHEHLMSQTSSSDSNG------QEESHRRRSGIFKTSGKIQTKSHVSHESGGQKEASVAEMQSSPPAQVKAVTTIERDSSGASLPKASFPEELAYKNQPPCSYQQISCLDSVIRYLESCSEAATLKRKCEFPANIPS------RKATVSPGLHSGEAARPSKVTS-------------HTEVSAHLSSLTLPGKAESVVSLTSQCSYSSTIVHVGDKKPQPE--------------LETVEDMAS--GPESLDGAAG-----GLSQEKGPLQKLGLTKEVLAAHTQKEEQGFLQRFREVSRLSALQAHCQNYLQERSRAQASDR---GLRNTSG----LESSWKKTGKNRKLKSKRVKTRDSSESTGSGGPVSHRPPLMGLNATAWSPSDTSQSSCPSAPFPTAVP-AYPLPVFQAPGIVSTPGTVVAPPAATHTGFTMPVVPMGTQPEFAVQPLPFAAPLA-PVMAFMLPSYPFPPATPNLPQAFLPS-QPHFPAHPTLASEITPASQAEFPSRTSTLRQ--------------------PCACPVTPPAG--------------TVALG---RASPPLFQSRGSSPLQLNLLQLEEAPEGSTGAAGTLG---TTGTAASGLDCTSGTSRDRQPKAPPTCNE--PSDTQNSDAISTSSDLLNLLLGEDLCSATGSALSRSGASATSDSLGSSSLGFGTSQSGAGSSDTS------HTSKYFGSIDSSENNHKAKMIPD----TEESEQFIKYVLQDPIWLLMANTDDSIMMTYQLPSRDLQAVLKEDQEKLKLLQRSQPRFTEGQRRELREVHPWVHTGGLPTAIDVTGCVYCESE-------EKGNICLPYEEDSPSPGLCDTSEAKEEEGEQLTGPRIEAQT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15055-1", "uniprot_id": "PER2_HUMAN", "id": "O15055-1", "name": "Period circadian protein homolog 2", "aln": "-----------------------------MNGYAEFPP----SPSNPTKEPVEPQPSQ--------VPLQEDVDMSS--GSSGH-------ETNENCSTGRDSQGSDCDDSG----KELGMLVEP-----PDAR----QSPD-TFSLMMAKSEH-NPSTSGCSSDQSSKVDTHKELIKTLKELKVHLPADKKAKG-KASTLATLKYALRSVKQVKAN------------EEYYQLLMSSEGHPCGADVPSYTVEEMESVTSEHIVKNADMFAVAVSLVSGKILYISDQVASIFHCKRDAFSDAKFVEFLAPHDVGVFHSFTSP-YKLPLWSMCSGADSFTQECMEEKSFFCRVSVRK-SHENEIRYHPFRMTPYLVKVRDQQGAE-------SQLCCLLLAERVHSGYEAPRIPPEKR--IFTTTHTPNCLFQDVDERAVPLLGYLPQDLIETPVLVQLHPSDRPLMLAIHKKILQ---SGGQPFDYSPIRFRARNGEYITLDTSWSSFINPWSRKISFIIGRHKVRVGPLNEDVFAAHPCTEEKALHPSIQELTEQIHRLLLQPVPHSGSSGYGSLGSNGSHEHLMSQTSSSDSNG------HEDSRRRRAEICKNGNKTKNRSHYSHESGEQKKKSVTEMQTNPPAEKKAVPAMEKDSLG-----VSFPEELACKNQPTCSYQQISCLDSVIRYLESCNEAATLKRKCEFPANVPALRSSDKRKATVSPGPHAGEAEPPSRVNS-------------RTGVGTHLTSLALPGKAESVASLTSQCSYSSTIVHVGDKKPQPE--------------LEMVEDAAS--GPESLDCLAGPALACGLSQEKEPFKKLGLTKEVLAAHTQKEEQSFLQKFKEIRKLSIFQSHCHYYLQERSKGQPSERTAPGLRNTSG----IDSPWKKTGKNRKLKSKRVKPRDSSESTGSGGPVSARPPLVGLNATAWSPSDTSQSSCPAVPFPAPVPAAYSLPVFPAP------GTVAAPPAPPHASFTVPAVPVDLQHQFAVQPPPFPAPLA-PVMAFMLPSYSFPSGTPNLPQAFFPS-QPQFPSHPTLTSEMASASQPEFPSRTSIPRQ--------------------PCACPATRATP--------------PSAMG---RASPPLFQSRSSSPLQLNLLQLEEAPEGGTGAMGTTG---ATETAAVGADCKPGTSRDQQPKAPLTRDE--PSDTQNSDALSTSSGLLNLLLNEDLCSASG--------SAASESLGSGSLGCDASPSGAGSSDTS------HTSKYFGSIDSSENNHKAKMNTG----MEESEHFIKCVLQDPIWLLMADADSSVMMTYQLPSRNLEAVLKEDREKLKLLQKLQPRFTESQKQELREVHQWMQTGGLPAAIDVAECVYCENK-------EKGNICIPYEEDIPSLGLSEVSDTKEDENGSPLNHRIEEQT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QFB2-1", "uniprot_id": "A0A8M9QFB2_DANRE", "id": "A0A8M9QFB2-1", "name": "Period circadian protein homolog 2", "aln": "MSEDLDSKPYLFSSLEGQDGAIGCSSMATLHRMASFAEGTELGLASEGSDSSQDRPTSGHNTRKMSHSLHEDVEMKSSSGSSGSGTESHGNESHGNESHGNESHGNESSGSSNSRSKDSALLVSSGSNKSSNSHSPSPPSSTNAFSLLSASSEQDNPSTSGCSSEESAKAKTQKELIKTLKELKLHLPAEKRNKGSKSTTLNTLKYALRCVRQVEAN------------EEYYQLLMINDSQPSGLDVSSYTIEEIDSITSEYTLKNTDIFAVAVSLITGKIVYISDQAASILNCKRDVFKNAKFVEFLTPQDVSVFYSFTTP-YRLPSWSMCTGADSSPSDCMQEKSFFCRISGGK-ECEADLQYYPFRMTPYLMKVQDMEHSE-------DQFCCLLLAERVHSGYEAPRIPTDKR--IFTTTHTPSCVFQDVDERAVPLLGYLPQDLIGTPVLLHLHPNDRPTMLGIHRKILQ---CAGQPFDHS-IRFCARNGEYITIDTSWSSFVNPWSRKVSFVIGRHKVRMGPVNEDVFAAPATAEGKCVDSDIQDITEQIHRLLLQPVHNNGSSGYGSLGSN---DHLLSVASSSESNGNGTRQRHEEEDIRKAKPRSFQEICKGVHMQKNQELQSKKSPTKFVQKSPVVRPKDSAYPVNWRESQEEQRAAVQEELAFKDQTVYSYQQISCLDSVIRYLESCNVPITVKRKCQSSSNTTSSNSDEDKQRNADSSMQVSEEPAHLKEQSGLSTLEVSKKPPGSGVVSPSLTPLALPSKPESVVSITSQCSYSSTIVHVGDKKVVSSTRHISTKQEYSSKLQKIIEDVPSAEGTDVQGLAVPPAAVSPQNQEREAYKKLGLTKQVLAAHTQKEEQAFLSRFRELRGVHAFKADCSLYLERQKGQVTSEAVPAARSCKAGGGGAQETTTTRRGRNKKTKSKRVKPNESSDSTPSGRRPAHRPQLQGLNQTSWSPSDTSQSTFP-IAYPAVMP-AYPLQMYPGA------GGMQPRVDAPMPGFGEGQCTPDPRIPMQPIQTPYSAPLVTPMVALVLPNYMFPQVGSAPRQAFYPPKQGPFPTQPTFQTQPGFTPQASFPPQTTFTIQTQFTSQNPFSSQPTFQPQPFPFACPEDPPKAPEPELREEQSRSPTPQSMGGGGPPSPPLFQSRCSSPLQLNLLQLEETQRSADRQENTAPSAVPLNNCSAGVEKAGSVTGQSKPVKDVVQDEGSPVDGQHSDALSSSSDLLDILP-EDSRSGTG--------SATSGSMGSGSNRCGTSASGGSASRTESSNKSNNSSNYFGSVDSSQKSHKAKAQGSGVLALDGSENLIKYVLQDPLWLLMANVDEDVMMSYQLPSRDIQKVLREDREKLRQMQKSQPRFTDEQKRELADVHPWMRRGGLPKAIDIKACMGCEELSEALNEDDPPDLHMGEAENSDVTAAPNSQELQEPPN-SPTHSCPGPDT", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P07663-1", "uniprot_id": "PER_DROME", "id": "P07663-1", "name": "Period circadian protein", "aln": "----------------MEGGESTESTHNTKVSDSAYSN----SCSNSQSQRSGSSKSR--------LSGSHSSGSSGYGGKPSTQASSSDMIIKRNKDKSRKKKKNKGAGQG---AGQAQTLISASTSLEGRDEEKPRPSGTGCVEQQICRELQDQQHGEDHSEPQAIEQLQQEEEEDQSGSESEADRVEGVAKSEAAQSFPIPSPLSVTIVPPSMGGCGGVGHAAGLDSGLAKFDKTWEAGPGKLESMTGVGAAAAGTGQRGERVKEDSFCCVISMHDGIVLYTTPSITDVLGYPRDMWLGRSFIDFVHLKDRATFASQITTGIPIAESRGSVPKDAKSTFCVMLRRYRGLKSGGFGVIGRPVSYEPFRLGLTFREAPEEARPDNYMVSNGTNMLLVICATPIKSSYKVPDEILSQKSPKFAIRHTATGIISHVDSAAVSALGYLPQDLIGRSIMDFYHHEDLSVMKETYETVMKKGQTAGASFCSKPYRFLIQNGCYVLLETEWTSFVNPWSRKLEFVVGHHRVFQGPKQCNVFEAAPTCKLKISEEAQSRNTRIKEDIVKR----------------------LAETVSRPSDT-----VKQEVSRRCQALASFMETLMDEVSRADLKLELPHENELTVSERDSVMLGEISPHHDYYDSKSSTETPPSYNQLNYNENLLRFFNSKPVTAPAELDPPKTEPPEPRGTCVSGASGPMSPVHEGSGGSGSSGNFTTASNIHMSSVT-------------NTSIAGTGGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTG-------------TGTGNGTNSGTGTGTASSSKG---------GSAAIPPVTLTESLLNKHNDEMEKFMLKKHRESRGRTGEKSKKSANDTLKMLEYSGPG----HGIKRG------GSHSWEGEANKPKQQLTLGTDAIKGAAGSAGGAVGTGGVGSGGAGVAGGGGSGTGVAGTPEGRATTTSGTGTPGGAGGGGGAGAAAAAGASSSVGSSTPGPSSYPTCTQNINLWPPFSVGITPPVHSTHTAMAQSSFSSAGLFPTFYYIPASLTPTSPTRSPRMHKHPHKGGTDMPTTSQQ---------------------AAAAAAQAMP--------------LQYMAGVMYPHPSLFYTHPAAAAATAMMYQPMPFPGMANALQIPERPLGSQSAYNKSVYTTTPASMTKKVPGAFHSVTTPAQVQRPSSQS-----------------------------ASVKTEPGSSAAVSDPCKKEVPDSS------PIPSVMGDYNSDPPCSSSNPANN-----------KKYTDSNGNSDDMDGSSFSSFYSSFIKTTDGSESPPDTEKDPKHRKLKSMSTSESKIMEHPEEDQTQHGDG----------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. . :. .: : .. .. *... : * . ....: .. ... : *:.. . * . : : .. *. :: : ::* . . .: *. : :: . : . . . :: :. * : : . .. : * *. .:*: * ::* : . : :: :* : . .*::*: :* ..* * :. :. . *: . *: : : * : * ***: : :. : . :: :: * ::*.*:.* .:: *: **.. ::. **. **. ********* .:: * .* . * :..::: .* .* . ** :** *: ::*.*:**:******:.*::*:*:* ** : :** * . : * . . *. . :: : :: : * *: ::: * . . . :. . . . .. : .: : : . : : . . . . : .* :. . . ... : :. . : ... .. : *. : :.* . .* . :. * *. . . : **:.:* *.:. *: :*.:.:* ::. : .. * . . *. .* *.: . :: ..: .. : . * . :. : .. * : . . . : . . . . .. . . *:.. :. *: : . . . :* *: ** .. .: . .: * *.. . :. . *.** :: ::. :: . . .. : : . * : *...: * :* . ..* :. . . :. .. :*. :*. .:: . * . .: * . . . : : : : : . : .:. : : . :: : * : . : .* ", "identical_positions": 121, "similar_positions": 368, "identity": "8.25%" }, { "cls_id": "homologset.agr.MGI:1195266", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B0BN34-1", "uniprot_id": "B0BN34_RAT", "id": "B0BN34-1", "name": "Tumor necrosis factor-inducible gene 6 protein", "aln": "MVFLLCLCVLLWEEAHGWGFKNGIFHNSIWLEQAAGVYHREARAGRYKLTYAEAKAVCEYEGGRLATYKQLEAARKIGFHVCAAGWMAKGRVGYPIVKPGPNCGFGKTGIIDYGIRLNRSERWDAYCYNPNAKECGGVFTDPKRIFKSPGFPNEYDDNQVCYWHIRLKYGQRIHLSFLDFDLEHDPGCLADYVEIYDSYDDVHGFVGRYCGDELPEDIISTGNVMTLKFLSDASVTAGGFQIKYVTVDPAPKSNQGKNTTMT--GNKKFLAGRFSHL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O08859-1", "uniprot_id": "TSG6_MOUSE", "id": "O08859-1", "name": "Tumor necrosis factor-inducible gene 6 protein", "aln": "MVVLLCLCVLLWEEAHGWGFKNGIFHNSIWLEQAAGVYHREARAGRYKLTYAEAKAVCEFEGGRLATYKQLEAARKIGFHVCAAGWMAKGRVGYPIVKPGPNCGFGKTGIIDYGIRLNRSERWDAYCYNPHAKECGGVFTDPKRIFKSPGFPNEYDDNQVCYWHIRLKYGQRIHLSFLDFDLEHDPGCLADYVEIYDSYDDVHGFVGRYCGDELPEDIISTGNVMTLKFLSDASVTAGGFQIKYVTVDPASKSSQAKNTSTT--GNKKFLPGRFSHL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P98066-1", "uniprot_id": "TSG6_HUMAN", "id": "P98066-1", "name": "Tumor necrosis factor-inducible gene 6 protein", "aln": "MIILIYLFLLLWEDTQGWGFKDGIFHNSIWLERAAGVYHREARSGKYKLTYAEAKAVCEFEGGHLATYKQLEAARKIGFHVCAAGWMAKGRVGYPIVKPGPNCGFGKTGIIDYGIRLNRSERWDAYCYNPHAKECGGVFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDPGCLADYVEIYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKYVAMDPVSKSSQGKNTSTTSTGNKNFLAGRFSHL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:.*: * :****:::*****:**********:**********:*:*************:***:******************************************************************:************:***********:***:***********************.*******************************:*****************************::**..**.*.***: * ***:**.******", "identical_positions": 244, "similar_positions": 28, "identity": "88.09%" }, { "cls_id": "homologset.agr.MGI:1195267", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99J82-1", "uniprot_id": "ILK_RAT", "id": "Q99J82-1", "name": "Scaffold protein ILK", "aln": "MDDIFTQCREGNAVAVRLWLDNTENDLNQGDDHGFSPLHWACREGRSAVVEMLIMRGARINVMNRGDDTPLHLAASHGHRDIVQKLLQYKADINAVNEHGNVPLHYACFWGQDQVAEDLVANGALVSICNKYGEMPVDKAKAPLRELLRERAEKMGQNLNRIPYKDTFWKGTTRTRPRNGTLNKHSGIDFKQLNFLAKLNENHSGELWKGRWQGNDIVVKVLKVRDWSTRKSRDFNEECPRLRIFSHPNVLPVLGACQAPPAPHPTLITHWMPYGSLYNVLHEGTNFVVDQSQAVKFALDMARGMAFLHTLEPLIPRHALNSRSVMIDEDMTARISMADVKFSFQCPGRMYAPAWVAPEALQKKPEDTNRRSADMWSFAVLLWELVTREVPFADLSNMEIGMKVALEGLRPTIPPGISPHVCKLMKICMNEDPAKRPKFDMIVPILEKMQDK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O55222-1", "uniprot_id": "ILK_MOUSE", "id": "O55222-1", "name": "Scaffold protein ILK", "aln": "MDDIFTQCREGNAVAVRLWLDNTENDLNQGDDHGFSPLHWACREGRSAVVEMLIMRGARINVMNRGDDTPLHLAASHGHRDIVQKLLQYKADINAVNEHGNVPLHYACFWGQDQVAEDLVANGALVSICNKYGEMPVDKAKAPLRELLRERAEKMGQNLNRIPYKDTFWKGTTRTRPRNGTLNKHSGIDFKQLNFLAKLNENHSGELWKGRWQGNDIVVKVLKVRDWSTRKSRDFNEECPRLRIFSHPNVLPVLGACQAPPAPHPTLITHWMPYGSLYNVLHEGTNFVVDQSQAVKFALDMARGMAFLHTLEPLIPRHALNSRSVMIDEDMTARISMADVKFSFQCPGRMYAPAWVAPEALQKKPEDTNRRSADMWSFAVLLWELVTREVPFADLSNMEIGMKVALEGLRPTIPPGISPHVCKLMKICMNEDPAKRPKFDMIVPILEKMQDK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13418-1", "uniprot_id": "ILK_HUMAN", "id": "Q13418-1", "name": "Scaffold protein ILK", "aln": "MDDIFTQCREGNAVAVRLWLDNTENDLNQGDDHGFSPLHWACREGRSAVVEMLIMRGARINVMNRGDDTPLHLAASHGHRDIVQKLLQYKADINAVNEHGNVPLHYACFWGQDQVAEDLVANGALVSICNKYGEMPVDKAKAPLRELLRERAEKMGQNLNRIPYKDTFWKGTTRTRPRNGTLNKHSGIDFKQLNFLTKLNENHSGELWKGRWQGNDIVVKVLKVRDWSTRKSRDFNEECPRLRIFSHPNVLPVLGACQSPPAPHPTLITHWMPYGSLYNVLHEGTNFVVDQSQAVKFALDMARGMAFLHTLEPLIPRHALNSRSVMIDEDMTARISMADVKFSFQCPGRMYAPAWVAPEALQKKPEDTNRRSADMWSFAVLLWELVTREVPFADLSNMEIGMKVALEGLRPTIPPGISPHVCKLMKICMNEDPAKRPKFDMIVPILEKMQDK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V400-1", "uniprot_id": "Q9V400_DROME", "id": "Q9V400-1", "name": "", "aln": "MEDIFHWCREGNSIQVRLWLDETEHDNNLGDDHGFSPLHWVAKEGHAKLVETLLQRGSRVNATNMGDDIPLHLAAAHGHRDVVQMLIKERSDVNAVNEHGNTPLHYACFWGYDMICEDLLNAGAQVGIANKDGHTPLEKAKPSLAKRLQDLVEKSGREVKVISFKEQSWQG-LKTRSRDATLSRFKGISMGDLDLHTKLSVTPSGETWRGRWQKNDVVAKILAVRQCTPRISRDFNEEFPKLRIFSHPNILPIIGACNSP--PNLVTISQFMPRSSLFSLLHGATGVVVDTSQAVSFALDVARGMAFLHSLERIIPTYHLNSHHVMIDDDLTARINMGDAKFSFQEKGRIYQPAWMSPETLQRKQADRNWEACDMWSFAILIWELTTREVPFAEWSPMECGMKIALEGLRVKIPPGTSTHMAKLISICMNEDPGKRPKFDMVVPILEKMRR-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:*** *****:: ******:**:* * ***********..:**:: :** *: **:*:*. * *** ******:*****:** *:: ::*:********.********* * :.***: ** *.*.** *. *::***..* : *:: .** *:::: *.:*: *:* :**.*:.**.:..**.: :*:: :**. . *** *:**** **:*.*:* **: :.* ******* *:********:**::***::* *: . *:::** .**:.:** .*..*** ****.****:********:** :** : ***: ****:*:****.*.*.***** **:* ***::**:**:* * * .:.******:*:***.*******: * ** ***:****** .**** *.*:.**:.*******.*******:*******: ", "identical_positions": 269, "similar_positions": 119, "identity": "59.51%" }, { "cls_id": "homologset.agr.MGI:1195268", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9R0C9-1", "uniprot_id": "SGMR1_RAT", "id": "Q9R0C9-1", "name": "Sigma non-opioid intracellular receptor 1", "aln": "MPWAVGRRWAWITLFLTIVAVLIQAVWLWLGTQSFVFQREEIAQLARQYAGLD---HELAFSRLIVELRRLHPGHVLPD-----EELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSHGHSGRYWAEISDTIISGTFHQWREGTTKSEVYYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPSTLAFALSDTIFSTQDFLTLFYTLRAYARGLRLELTTYLFGQDP-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O55242-1", "uniprot_id": "SGMR1_MOUSE", "id": "O55242-1", "name": "Sigma non-opioid intracellular receptor 1", "aln": "MPWAAGRRWAWITLILTIIAVLIQAAWLWLGTQNFVFSREEIAQLARQYAGLD---HELAFSRLIVELRRLHPGHVLPD-----EELQWVFVNAGGWMGAMCILHASLSEYVLLFGTALGSHGHSGRYWAEISDTIISGTFHQWKEGTTKSEVFYPGETVVHGPGEATALEWGPNTWMVEYGRGVIPSTLFFALADTFFSTQDYLTLFYTLRAYARGLRLELTTYLFGQDS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99720-1", "uniprot_id": "SGMR1_HUMAN", "id": "Q99720-1", "name": "Sigma non-opioid intracellular receptor 1", "aln": "MQWAVGRRWAWAALLLAVAAVLTQVVWLWLGTQSFVFQREEIAQLARQYAGLD---HELAFSRLIVELRRLHPGHVLPD-----EELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSRGHSGRYWAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPSTLAFALADTVFSTQDFLTLFYTLRSYARGLRLELTTYLFGQDP-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZWG9-1", "uniprot_id": "SGMR1_DANRE", "id": "Q7ZWG9-1", "name": "Sigma non-opioid intracellular receptor 1", "aln": "--MSLIRTILKLVVVVGFLSLTVQFIRHWMANKQYVFTKEEVAKLAKQYAGQD---HEQAFSKVVVELRRRYPGHILPD-----EDLQWVFVNAGGWMGSMCLLHASLTEYVLLFGTAVDTGGHSGRYWAEISDTIISGTFRQWKEGTTKSETYYPGDTIVHSAGEATSVQWSSGTWMVEYGRGFIPSTLGFALADTMFSTQDFLTLFYTARVYVKGMILEASTFLTESGVL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P32352-1", "uniprot_id": "ERG2_YEAST", "id": "P32352-1", "name": "C-8 sterol isomerase ERG2", "aln": "------MKFFPLLLLIGVVGYIMNVLFTTWLPTNYMFDPKTLNEICNSVISKHNAAEGLSTEDLLQDVRDALASHYGDEYINRYVKEEWVFNNAGGAMGQMIILHASVSEYLILFGTAVGTEGHTGVHFADDYFTILHGTQIAALPYATEAEVYTPGMTHHLKKGYAKQYSMPGGSFALELAQGWIPCMLPFGFLDTFSSTLDLYTLYRTVYLTAR----DMGKNLLQNKKF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.: . . : .::* : : ::... . . . : . :: ::* ..* : . :*** **** ** * :****::**::*****:.: **:* ::*: **: ** :*::*.: ** * * *. . .:: :* .:* **. * *.: **. ** * **: * .: : . * . ", "identical_positions": 54, "similar_positions": 66, "identity": "23.28%" }, { "cls_id": "homologset.agr.MGI:1195269", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3ZAV1-1", "uniprot_id": "S22AC_RAT", "id": "Q3ZAV1-1", "name": "Solute carrier family 22 member 12", "aln": "--------------MAFPELLD-RVGGRGRFQLLQAVALVTPILWVTTQNMLENFSAAVPHH--RCWVPLLDN-STSQASIPGDFGR---DVLLAVSIPPGPDQRPHQCLRFRQPQWQLIESNTTATNWSDADT------EPCEDGWVYDHSTFRS-------------TIVTTWDLVCDSQALRPMAQSIFLAGILVGAAVCGHASDRFGRRRVLTWSYLLVSVSGTIAALMPTFPLYCLFRFLVASAVAGVMMNTASLLMEWTSAQAGPLMMTLNALGFSFGQVLTGSVAYGVRSWRMLQLAVSAPFFLFFVYSWWLPESARWLITVG-----RLDQSLRELQRVAAVNRRKAEADTLTVEVLRSAMQEEPNGNQAGARLGTLLHTPGLRLRTFISMLCWFAFGFTFYGLALDLQALG-SNIFLLQALIGIVDLPVKMGSLLLLSRLGRRLCQAS---SLVLPGLCILANILVPREMGILR-----SSLAVLGLGSLGAAFTCVTIFSSELFPTVIRMTAVGLGQVAARGGAMLGPLVRLLGVYGSWLPLLVYGVVPVLSGLAALLL---------PETKNLPLPDTIQDIQKQSVKKVTHDIAGGSVLKSARL---------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CFZ5-1", "uniprot_id": "S22AC_MOUSE", "id": "Q8CFZ5-1", "name": "Solute carrier family 22 member 12", "aln": "--------------MAFPELLD-RVGGLGRFQLFQTVALVTPILWVTTQNMLENFSAAVPHH--RCWVPLLDN-STSQASIPGDLGP---DVLLAVSIPPGPDQQPHQCLRFRQPQWQLTESNATATNWSDAAT------EPCEDGWVYDHSTFRS-------------TIVTTWDLVCNSQALRPMAQSIFLAGILVGAAVCGHASDRFGRRRVLTWSYLLVSVSGTAAAFMPTFPLYCLFRFLLASAVAGVMMNTASLLMEWTSAQGSPLVMTLNALGFSFGQVLTGSVAYGVRSWRMLQLAVSAPFFLFFVYSWWLPESARWLITVG-----KLDQGLQELQRVAAVNRRKAEGDTLTMEVLRSAMEEEPSRDKAGASLGTLLHTPGLRHRTIISMLCWFAFGFTFYGLALDLQALG-SNIFLLQALIGIVDFPVKTGSLLLISRLGRRFCQVS---FLVLPGLCILSNILVPHGMGVLR-----SALAVLGLGCLGGAFTCITIFSSELFPTVIRMTAVGLCQVAARGGAMLGPLVRLLGVYGSWMPLLVYGVVPVLSGLAALLL---------PETKNLPLPDTIQDIQKQSVKKVTHDTPDGSILMSTRL---------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96S37-1", "uniprot_id": "S22AC_HUMAN", "id": "Q96S37-1", "name": "Solute carrier family 22 member 12", "aln": "--------------MAFSELLD-LVGGLGRFQVLQTMALMVSIMWLCTQSMLENFSAAVPSH--RCWAPLLDN-STAQASILGSLSP---EALLAISIPPGPNQRPHQCRRFRQPQWQLLDPNATATSWSEADT------EPCVDGWVYDRSIFTS-------------TIVAKWNLVCDSHALKPMAQSIYLAGILVGAAACGPASDRFGRRLVLTWSYLQMAVMGTAAAFAPAFPVYCLFRFLLAFAVAGVMMNTGTLLMEWTAARARPLVMTLNSLGFSFGHGLTAAVAYGVRDWTLLQLVVSVPFFLCFLYSWWLAESARWLLTTG-----RLDWGLQELWRVAAINGKGAVQDTLTPEVLLSAMREELSMGQPPASLGTLLRMPGLRFRTCISTLCWFAFGFTFFGLALDLQALG-SNIFLLQMFIGVVDIPAKMGALLLLSHLGRRPTLAA---SLLLAGLCILANTLVPHEMGALR-----SALAVLGLGGVGAAFTCITIYSSELFPTVLRMTAVGLGQMAARGGAILGPLVRLLGVHGPWLPLLVYGTVPVLSGLAALLL---------PETQSLPLPDTIQDVQNQAVKKATHGTLGNSVLKSTQF---------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VDS2-1", "uniprot_id": "Q9VDS2_DROME", "id": "Q9VDS2-1", "name": "", "aln": "--------------MKKDNLYRGWMPNIRRNSPAPLDLGHMAHSFTCTDPKANEVSPQTPHP--KANNLADDNDDDVITHIMGNFGPWQLRSLLILFLCKIPAAWFMACILFTAPDLYPEEEYKCDTTAFGPDVNSTVSLDHCYVMVNYGESAYAMRQCRKFLYTTGFHSLTMEFDLVCLCDFFVAWSQYWHLFGLLIGGVAATKLMRVLSPRQIYRTGIWCLLMCSLLMGLVKDFSLHCGLRCLAAVSCCFMITSGQYIFGDITAGKYRVGTLILYDCFWALGLILLPGLASNAPSWQHIYLGVTLSLLVIVFLLPWTPDSPRWQLQHTKEAQLAIERTVGILLEAARTNGRMHKVSKELPQQLEELRERMLEPMPAVHWMHLWMGQRRSTFHLVAVHMALATFMVVNTGLLLHVRSFGREHLVSNTLAMGLAEMLGCFLALHLTFNLSERKWQWAGGFAIVVGCIGSICWFLAEEDMPEVYGLTLGLLMASLPQAAVACAQSMILACLGELVPMEQRSCLSFSAVTWARVWQLSASFLTLLRQVSPALSLSAFCLLVILGGLGTCCL---------VTRDKEQPPVGAVVNKGQQLIAFT-----------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VDR9-1", "uniprot_id": "Q9VDR9_DROME", "id": "Q9VDR9-1", "name": "Solute carrier family 22 member 3", "aln": "MTDSQSMGSIPRKSSPELDVVEQVNGSFGRWQLRTILLIFLCKIPSAWFTAIIIYTAPYPWKGELVCHPADWNVSRSQTEHVDRNHPLWQDARSTDRLFNVDVCNAYSNSLARGFVRSHGQEWNASQSKEPGGQ------SSLPCEHVEHRTDYKS--------------LISQFDLICSRRVLVALTQSFHALGALIGGLMAYSALKKISPRRLMLLGMIGQIFCGNLTGLVDTYQLHIYFRCLTSIFCALMYTSGQFILNDITSGKARIIVVTLSELFWSMGLVLLPAISIYFDNWSYLYVAISSSLIVLVWLHRWIADAPRWLLQHQ-----RVEAALRQLLESATYNNR--KVPLTLDVQLTMYANDLDQKSKQKHSYCQVWDGETKRSQLVYIHLIWGGAMVLYNIILLMIRNLGAQQVHVNTAAMGFAEMVGLFVGLYLILYT-RRHWRWAGN-LMIIAGLSTYLIWLLPETERNSRRVGLELVFWLILKIANSASIAVLTTCTSEIVSKEKRVVLMLSVISFSRVCLLFCPFLSCLTVIHHLVPITILATMGWIYGLALRRLNRYYWNTEQPQISQVPTPNTYRRQSAIILRRCSTVSSDCSAYSNELLSNFERNMAVSIADIWHINFHPSSEIEMEVEQSGPEAHRAHSSETI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: . * . :. * * . : . : : . . .: : : ::*:* : . :* . * *:*. . :. * : . . . .: : :: :* * : . : . :: : *:.: : * :::* * .:: .* : : :: .::: . * .::.** : :: : * . * * : * . . : : . : * :: :* .:: :*..:: .* * .* : ::: : * . : : . : : : .*:.. * :* : .:: * :.: : : **. * .. * . : : ", "identical_positions": 39, "similar_positions": 127, "identity": "5.9%" }, { "cls_id": "homologset.agr.MGI:1195270", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O08781-1", "uniprot_id": "ZMAT3_RAT", "id": "O08781-1", "name": "Zinc finger matrin-type protein 3", "aln": "----------------------------------------------------------------------------------------MILLQQVWLPLPNRPSTS--PPMSVAARSTGTLQLPPQKAFGQEASLP---------------------------------------------------------------LAGEEDLAKRGEPDSAL--------------------------------------------------------EELCKPLFCKLCNVTLNSAQQAQAHYQGKNHGKKLR----------NYYAANSCP------PPARMSS---------------------------------VAEPVATPLVPVPPQVGS--------CKPGGRVILATENDYCKLCDASFSSPAVAQAHYQGKNHAKRLR---LAEAQSHSFSDSAEAGQRRTRKEGSEFKMVTTRRN-MYTVQSN-SGPYFNARSRQRIP--------RDLAMCVTPSGQFYCSMCNVGAGEEVEFRQHLESKQHKSKVSEQRYRSEMENLGYVQ-------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O54836-1", "uniprot_id": "ZMAT3_MOUSE", "id": "O54836-1", "name": "Zinc finger matrin-type protein 3", "aln": "----------------------------------------------------------------------------------------MILLQQVWLPLPNRPSTS--PPMSVAARSTRTLQLPPQKAFGQEASLP---------------------------------------------------------------LAGEEDLAKRGEPDSAL--------------------------------------------------------EELCKPLFCKLCNVTLNSAQQAQAHYQGKNHGKKLR----------NYYAANSCP------PPARVSSV--------------------------------VAEPVATPLVPVPPQVGS--------CKPGGRVILATENDYCKLCDASFSSPAVAQAHYQGKNHAKRLR---LAEAQSHSFSDSAEAGQRRTRKEGSEFKMVATRRN-MNPVQSN-SGPYFNARSRQRIP--------RDLAMCVTPSGQFYCSMCNVGAGEEVEFRQHLESKQHKSKVSEQRYRSEMENLGYVQ-------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HA38-1", "uniprot_id": "ZMAT3_HUMAN", "id": "Q9HA38-1", "name": "Zinc finger matrin-type protein 3", "aln": "----------------------------------------------------------------------------------------MILLQHAVLPPPKQPSPS--PPMSVATRSTGTLQLPPQKPFGQEASLP---------------------------------------------------------------LAGEEELSKGGEQDCAL--------------------------------------------------------EELCKPLYCKLCNVTLNSAQQAQAHYQGKNHGKKLR----------NYYAANSCP------PPARMSN---------------------------------VVEPAATPVVPVPPQMGS--------FKPGGRVILATENDYCKLCDASFSSPAVAQAHYQGKNHAKRLR---LAEAQSNSFSESSELGQRRARKEGNEFKMMPNRRN-MYTVQNNSAGPYFNPRSRQRIP--------RDLAMCVTPSGQFYCSMCNVGAGEEMEFRQHLESKQHKSKVSEQRYRNEMENLGYV--------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7EZ09-1", "uniprot_id": "E7EZ09_DANRE", "id": "E7EZ09-1", "name": "Zinc finger matrin-type protein 3", "aln": "----------------MAMNVKNRDAFYSGADYCNIYSSQPVNYGDCSHYFPRITGPDPILKPPISL----------MCQQPPQPFQAMTPTQNLRPPPVMMPDPLPFPHCTPPIKPPPHLQLPPNPPLPPPPVISPK-------------------------------------------------------------PPEEDAQAVAADQEATL--------------------------------------------------------EELCKPLYCKLCNVTLNSAQQAQAHYQGKNHSKKLR----------NFYAGSQQP------PPITIPE---------------------------------VVEPVSQQPSATTPTDSANATANQPLTKGASRVILATENDYCKLCDASFSSPAVAQAHYQGKNHAKRLR---LAEAQQNATSSDLSDTQRRPRKEGYEYRLMKNRRA-QFNTAMP--GPYYNPRPRQRIP--------RDLAMCVTPSGQFYCSMCNSGASEEAEFRLHLESKQHKSRVSEQRYRSEMENLGYT--------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VKS7-1", "uniprot_id": "Q9VKS7_DROME", "id": "Q9VKS7-1", "name": "", "aln": "MLSHAFNMHPQRRVPVIHEQIAKQCALNIVRVASAMPQPQPRCPSGHVVVLVELRRTDEQTVHRYQVNVPPTGWTNEDLEEEEKRFQQLVLPGTLDSMGLKLPLPER-PPCPMHGRSIMEMGWSPNSNMGPPPMLMIQSSVHITNGQDGATDFATFREPVVTSESPDNLRAHFMASLYQQQPSPLSYSDIWVSDSPSTGLPRSEALSTTHFPQFYLGENAESMVANKIRPINGYPINGYPISGYPTVPRPAVKKPRHVAELCLDSNGEYVLNKQLHQPLISRQPDPIIPSVSSRDPHYFIQNQSHQLESAIKGLNGYTNVAQESEKPKNGYKYQPAAFADQRIVLQPKLGQGQGQAQGAVPGFIPNHLQSRVAMVEPRIRQESLIKPQNPDLALPSEAHPPVPQDLQSLFRWNYCALCNMVIRSTQSAIDHYSSRAHERRISSWLVRKCYANLTGRDADALGGAISQSEFYCKLCDLKLTSLSHAQQHFLGRRHRIAARHRIRPFSDGFYDREGNWVRTDIKYPMCELCDVIITSESQMAMHLAGARHRRRVQIAYAGESAGGMEMGIGLVPFDGSHMYRIRGNGSLAPIRPLGSQLLQGSAYPLSLTDPSAVFYCDACNITLNHLKSVNQHEQGRMHRRNMHRLPAQAVFFE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W0R2-1", "uniprot_id": "Q9W0R2_DROME", "id": "Q9W0R2-1", "name": "Matrin-type domain-containing protein", "aln": "--------------------MSCPGSLRGFHIPHLAPGETPKIRVDSACIES-------------------------------HPDAEISTSNRLVAPGKRTDKKDNGSIRTNMKRKAKCMEEDSLKANGDLALFP----------------------------------------------------------------GRDESYPEELN--------------------------------------------------------------RLIGPLNCQLCKVQMTSRKRARDHYESKAHDRHIS----------AWLAKNYTEVG--------------------------------------------LEAPPVKRLAKQGPTGPN--------------------AFHCELCNLDLTSSMHARQHYLGRKHKRVEQG-----VAKPSGARHCDTSVGRYGIGSLFRKPESLTKD---------------SPTDVLIS---------ENSVIKSDDNERTCHLCKIVVTSAAQMQAHLAGARHQKNWRTSRQDQNHSEAPIPET--------------------------EKLDAAELALYR-TPMGQYYCQPCNMMMNHESTLQQHFIGKKHLKRVKNLSQTEKNV-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . : : . . : .: . .* ** .: . : * . ** : :.::: . : * * :* **: : *. * ** .: * : . . : . * : : * :*. . :: ** . :*: . .. ", "identical_positions": 22, "similar_positions": 49, "identity": "3.37%" }, { "cls_id": "homologset.agr.MGI:1195271", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P56404-1", "uniprot_id": "AQP8_MOUSE", "id": "P56404-1", "name": "Aquaporin-8", "aln": "--------MSGEQTPMCSMDLPEVKVK-TSMAGRCR-VFWYEQYVQPCIVELVG--SALFIFIGCLSVIENSP--------------NTGLLQPALAHGLALGLIIATLGNISGGHFNPAVSLAVTVIGGLKTMLLIPYWISQLFGGLIGAALAKVVSPEERFWNASGAAFAIVQEQEQVAEALGIEIILTMLLVLAVCMGAVNEKTMGPLAPFSIGFSVIVDILAGGSISGACMNPARAFGPAVMAGYWD-FHWIYWLGPLLAGLFVGLLIRLLIGDEKTRLILKSR-----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P56405-1", "uniprot_id": "AQP8_RAT", "id": "P56405-1", "name": "Aquaporin-8", "aln": "--------MSGEQTPMCSMDLREIKGKETNMADSYHGMSWYEQYIQPCVVELLG--SALFIFIGCLSVIENSP--------------NTGLLQPALAHGLALGLIIATLGNISGGHFNPAVSLAVTLVGGLKTMLLIPYWVSQLFGGMIGAALAKVVSPEERFWNASGAAFAIVQEQEQVAEALGVEIVMTMLLVLAVCMGAVNEKTMGPLAPFSIGFSVIVDILAGGGISGACMNPARAFGPAVMAGYWD-FHWIYWLGPLLAGLFVGLLIRLFIGDEKTRLILKSR-----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O94778-1", "uniprot_id": "AQP8_HUMAN", "id": "O94778-1", "name": "Aquaporin-8", "aln": "--------MSG-EIAMCEPEFGNDKAREPSVGGRWR-VSWYERFVQPCLVELLG--SALFIFIGCLSVIENGT--------------DTGLLQPALAHGLALGLVIATLGNISGGHFNPAVSLAAMLIGGLNLVMLLPYWVSQLLGGMLGAALAKAVSPEERFWNASGAAFVTVQEQGQVAGALVAEIILTTLLALAVCMGAINEKTKGPLAPFSIGFAVTVDILAGGPVSGGCMNPARAFGPAVVANHWN-FHWIYWLGPLLAGLLVGLLIRCFIGDGKTRLILKAR-----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NFX9-1", "uniprot_id": "A0A8M1NFX9_DANRE", "id": "A0A8M1NFX9-1", "name": "", "aln": "--------MADDKMEKAAMDKMVQETEMEEPG-------LFEQLVQPCMAELVG--TAFFVLMGCLCVIESAQ--------------EGHTLQAALVHGLALAVVIGCMVEISGSHFNPSFTIAVFLSGGLELKMVLPYLISQVSGGLLGAVMAKGMTSSEKYAQAQGAAFTVLQADDHIMKALFAEAAMTCLATLAVLLSAVNGKSKNHMFPFLVGCTVMVNVLAGANVSGACLNPVRALGPAVLTNYWT-HHWIYWVGPITGGLIAAALVRLFLGDNDTRVVMK-------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P0CD91-1", "uniprot_id": "AQY1_YEAST", "id": "P0CD91-1", "name": "Aquaporin-1", "aln": "MSSNDSNDTDKQHTRLDPTGVDDAYIPPEQPETKHHRFKISRDTLRDHFIAAVGEFCGTFMFLWCAYVICNVANHDVALVAAPDGSHPGQLIMIAIGFGFSVMFSIWCFAGVSGGALNPAMSLSLCLARAVSPTRCVVMWVSQIVAGMAAGGAASAMTPGEVLFANS------LGLGCSRTRGLFLEMFGTAILCLTVLMTAVEKRETNFMAALPIGISLFIAHVALTAYTGTGVNPARSLGAAVAARYFPHYHWIYWIGTLLGSILAWSVWQLLQILDYTTYVTAEKAASTKEKAQKKGETSSSSAVAEV", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P0CD98-1", "uniprot_id": "YLL53_YEAST", "id": "P0CD98-1", "name": "Putative uncharacterized protein YLL053C", "aln": "------------------------------------------------------------------------------------------------------------------------------------------MWFPQIIAGMAAGGAASAMTPGKVLFTNA------LGLGCSRSRGLFLEMFGTAVLCLTVLMTAVEKRETNFMAALPIGISLFMAHMALTGYTGTGVNPARSLGAAVAARYFPHYHWIYWISPLLGAFLAWSVWQLLQILDYTTYVNAEKAAG-----QKKED----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ..*: .*: .. *. ::. : : .* * * : *:* : *:: : . : .: :* :: : :* :* :**.*::*.** : :: .*****:..: ..::. : : : * : ", "identical_positions": 24, "similar_positions": 52, "identity": "7.72%" }, { "cls_id": "homologset.agr.MGI:1195272", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A096MIW0-1", "uniprot_id": "A0A096MIW0_RAT", "id": "A0A096MIW0-1", "name": "Ectodysplasin-A", "aln": "MGYPEVERREPLPAAAPRERGSQGCGCRGAPARAGEGNSCRLFLGFFGLSLALHLLTLCCYLELRS--------ELRRERGTESRLGGPGAPGTSGTLSSPGSLDPVGPITRHLGQPSFQQQPLEPGEDPLPPDSQDRHQMALLNFFFPDEKPYSEEESRR--VRRNKRSKSGEGADGPVKNKKKGKKAGPPGPNGPPGPPGPPGPQGPPGIPGIPGIPG--TTVMGPPGPPGPPGPQGPPGLQGPSGAADKTGTRENQPAVVHLQGQGSAIQVKNDLSGGVLNDWSRITMNPKVFKLH-------------------PRSGELEVLVDGTYFIYSQVEVYYINFTDFASYEVVVDEKPFLQCTRSIETGKTN-YNTCYTAGVCLLKARQKIAVKMVHADISINMS--KHTTFFGAIRLGEAPAS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O54693-1", "uniprot_id": "EDA_MOUSE", "id": "O54693-1", "name": "Ectodysplasin-A", "aln": "MGYPEVERREPLPAAAPRERGSQGCGCRGAPARAGEGNSCRLFLGFFGLSLALHLLTLCCYLELRS--------ELRRERGTESRLGGPGAPGTSGTLSSPGSLDPVGPITRHLGQPSFQQQPLEPGEDPLPPDSQDRHQMALLNFFFPDEKAYSEEESRR--VRRNKRSKSGEGADGPVKNKKKGKKAGPPGPNGPPGPPGPPGPQGPPGIPGIPGIPG--TTVMGPPGPPGPPGPQGPPGLQGPSGAADKTGTRENQPAVVHLQGQGSAIQVKNDLSGGVLNDWSRITMNPKVFKLH-------------------PRSGELEVLVDGTYFIYSQVEVYYINFTDFASYEVVVDEKPFLQCTRSIETGKTN-YNTCYTAGVCLLKARQKIAVKMVHADISINMS--KHTTFFGAIRLGEAPAS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92838-1", "uniprot_id": "EDA_HUMAN", "id": "Q92838-1", "name": "Ectodysplasin-A", "aln": "MGYPEVERRELLPAAAPRERGSQGCGCGGAPARAGEGNSCLLFLGFFGLSLALHLLTLCCYLELRS--------ELRRERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDGHQMALLNFFFPDEKPYSEEESRR--VRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGPPGPPGPQGPPGIPGIPGIPG--TTVMGPPGPPGPPGPQGPPGLQGPSGAADKAGTRENQPAVVHLQGQGSAIQVKNDLSGGVLNDWSRITMNPKVFKLH-------------------PRSGELEVLVDGTYFIYSQVEVYYINFTDFASYEVVVDEKPFLQCTRSIETGKTN-YNTCYTAGVCLLKARQKIAVKMVHADISINMS--KHTTFFGAIRLGEAPAS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8MUJ1-1", "uniprot_id": "EIGER_DROME", "id": "Q8MUJ1-1", "name": "Tumor necrosis factor family member eiger", "aln": "--MTAETLKPFITPTSANDDGFPAKATSTATAQRRTRQLIPLVLGFIGLGLVVAILALTIWQTTRVSHLDKELKSLKRVVDNLQQRLGINYLDEFDEFQKEYENALIDYPKKVDGLTDEEDDDDGDGLDSIADDEDDDVSYSSVDDVGADYEDYTDMLNKLNNAHTGTTPTSETTAEGEGETDSASSASNDDNVFDDFTSYNAHKKKQERKSRSIADVRNEEQNIQGNHTELQEKSSNEATSKESPAPLHHRRRMHSRHRHLLVRKGESLLSARSEDSRPAAHFHLSSRRRHQGSMGYHGDMYIGNDNERNSYQGHFQTRDGVLTVTNTGLYYVY--AQICYNNSHDQNGFIVFQGDTPFLQCLNTVPTNMPHKVHTCHTSGLIHLERNERIHLKDIHNDRNAVLREGNNRSYFGIFKV------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : :..::..: * . . *.*: : *.***:**.*.: :*:* : * .*:* . .: * . . . :.. . . * .. ::: * .: *.:* . : :: . .* : *:: .: .: .. ..* *:* :... .. :. . . . .. : .*..: . .: * ..: ... :.*: .: :..: :: :*:. .:* .. . * : : * .*.* * * * *::* .:: * * * .: *. .:.***** .:: *. .: :**:*:*: *: .::* :* :* * . : :: ::** ::: ", "identical_positions": 60, "similar_positions": 149, "identity": "14.12%" }, { "cls_id": "homologset.agr.MGI:1195273", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O55237-1", "uniprot_id": "CD70_MOUSE", "id": "O55237-1", "name": "CD70 antigen", "aln": "MPEEGRPCPWVRWSGTAFQRQWPWLLLVVFITVFCCWFHCSGLLSKQQQRLLEHPEPHTAELQLNLTVPRKDPTLRWGAGPALGRSFTHGPELEEGHLRIHQDGLYRLHIQVTLANCSSPGSTLQHRATLAVGICSPAAHGISLLRGRFGQDCTVALQRLTYLVHGDVLCTNLTLPLLPSRNADETFFGVQWICP-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "M0R613-1", "uniprot_id": "M0R613_RAT", "id": "M0R613-1", "name": "CD70 antigen", "aln": "MPEEGRPYPWVRWSWSAFQRLLPWLLMVIIA--ICWWLLCGGHLSKPQHVLLEPPELHVAELQLNLTDPQKDLTLRWGAGPALGRSFTHGPGLEKGNLRIHQDGIYRLHIQVTLANCSSSGSALQHRASLVVGICSPAVHSISLLRRRFGQDCTVSLQRLTPLARGDVLCSNLTQPLLPSRNADETFFGVQRVTPA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P32970-1", "uniprot_id": "CD70_HUMAN", "id": "P32970-1", "name": "CD70 antigen", "aln": "MPEEGSGCSVRRRPYGCVLRAALVPLVAGLV--ICLVVCIQRFAQAQQQLPLESLGWDVAELQLNHTGPQQDPRLYWQGGPALGRSFLHGPELDKGQLRIHRDGIYMVHIQVTLAICSSTTASRHHPTTLAVGICSPASRSISLLRLSFHQGCTIASQRLTPLARGDTLCTNLTGTLLPSRNTDETFFGVQWVRP-", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***** . * . .. * *:. : :* . . *: ** ..****** * *::* * * .******** *** *::*:****:**:* :******* ***. :: :* ::*.******* :.***** * *.**:: **** *.:**.**:*** .******:******** : * ", "identical_positions": 98, "similar_positions": 41, "identity": "50.0%" }, { "cls_id": "homologset.agr.MGI:1195275", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P50170-1", "uniprot_id": "RDH16_RAT", "id": "P50170-1", "name": "Retinol dehydrogenase 16", "aln": "----------MWLYLLALVGLWNLLRLFRERKVVSHLQDKYVFITGCDSGFGNLLARQLDRRGMRVLAACLTEKGAEQLRSKTS-DRLETVILDVTKTESIVAATQWVKERVGNTGLWGLVNNAGISGHLGPNEWMNKQNIASVLDVNLLGMIEVTLSTVPLVRKARGRVVNVASIAGRLSF-CGGGYCISKYGVEAFSDSLRRELSYFGVKVAIVEPGFFRTDVTNGVTLSSNFQMLWDQTSSEVREVYGENYLASYLKMLN-GLDQRCNKDLSLVTDCMEHALTSCHPRTRYSAGWDAKFFYLPMSYLPTFLVDALFYWTSPKPEKAL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CGV4-1", "uniprot_id": "Q8CGV4_MOUSE", "id": "Q8CGV4-1", "name": "", "aln": "----------MWLYLVALVGLWTLLRFFRERQVVSHLQDKYVFITGCDSGFGNLLARQLDRRGMRVLAACLTEKGAEELRNKTS-DRLETVILDVTKTESIVAATQWVKERVGNRGLWGLVNNAGISTPSGPNEWMKKQDFARVLDVNLLGMIEVTLSMLPLVRKARGRVVNVSSVMGRMSF-FGGGYCISKYGVEAFSDSLRRELSYFGVKVAIIEPGGFKTCVTSSDRLSSNTKMIWDKASSEVKEIYGEKFLLFYLKNLN-ELDKRCNKDLSVVTDCMEHALTACHPRTRYSAGWDAKFLFLPLSYLPTFLVDALLYWTSMKPEKAL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75452-1", "uniprot_id": "RDH16_HUMAN", "id": "O75452-1", "name": "Retinol dehydrogenase 16", "aln": "----------MWLYLAVFVGLYYLLHWYRERQVLSHLRDKYVFITGCDSGFGKLLARQLDARGLRVLAACLTEKGAEQLRGQTS-DRLETVTLDVTKTESVAAAAQWVKECVRDKGLWGLVNNAGISLPTAPNELLTKQDFVTILDVNLLGVIDVTLSLLPLVRRARGRVVNVSSVMGRVSL-FGGGYCISKYGVEAFSDSLRRELSYFGVKVAMIEPGYFKTAVTSKERFLKSFLEIWDRSSPEVKEAYGEKFVADYKKSAE-QMEQKCTQDLSLVTNCMEHALIACHPRTRYSAGWDAKLLYLPMSYMPTFLVDAIMYWVSPSPAKAL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B7R1-1", "uniprot_id": "A0ACD6B7R1_DANRE", "id": "A0ACD6B7R1-1", "name": "", "aln": "MVFCCADLLCSCWCSLAVIALIAAVWFFRDSRQISGIHEKHVLITGCDSGFGNLVARQLDRQGFLVIAACLTETGASKLRATAS-PRLKTLQLNVTDSTSIDRALEYVRRETGGKGLWGLVNNAGVSVPIGPMDWMQLHDFKKVLDVNLTGVIAVTLKFLPLLKKAQGRVVNVASILGRLSI-IGGGYCLSKFGVEAFSDSLRRDMVHFGVKVSIIEPGFFKTQVTDLGLIEDDLKKRWSNLPEQVRRDYGDSYLQEYLKVLEFSHKMLASSDLSKVTSCMRHALSARHPRTRYAAGWDAKFLWIPLSYLPTCVVDIITKALVPS-SKPL-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P40471-1", "uniprot_id": "AYR1_YEAST", "id": "P40471-1", "name": "NADPH-dependent 1-acyldihydroxyacetone phosphate reductase", "aln": "------------------------------MSELQSQPKKIAVVTGASGGIGYEVTKELARNGYLVYACARRLEPMAQLAIQFGNDSIKPYKLDISKPEEIVTFSGFLRANLPDGKLDLLYNNAGQSCTFPALDATD-AAVEQCFKVNVFGHINMCRELSEFLIKAKGTIVFTGSLAGVVSFPFGSIYSASKAAIHQYARGLHLEMKPFNVRVINAITGGVATDIADKRPLPETSIYNFPEGREAFNSRK--TMAKDNKPMPADAYAKQLVKDILSTSDPVDVYRGTFANIMRFVMIFVP-YWLLEKGLSKKFKLDKVNNALKSKQKNKDD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. .* ..:**...*:* ::::* .* * *.. :* . ::. *:::.. .: ::: . * * **** * . : . :.**: * * : . :: :*:* :* ..*: * :*: *. *. ** .:. :: .*: :: *.*:* .* . * ::. : . : . .. . .*: .:. : : *: : . : . . :* : . : ", "identical_positions": 41, "similar_positions": 93, "identity": "12.39%" }, { "cls_id": "homologset.agr.MGI:1195276", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZKU7-1", "uniprot_id": "BL1S1_RAT", "id": "D3ZKU7-1", "name": "Biogenesis of lysosome-related organelles complex 1 subunit 1", "aln": "----------------------------MLSRLLKEHQAKQNERKELQEKRRREAITAATCLTEALVDHLNVGVAQAYMNQRKLDHEVKTLQVQAAQFAKQTGQWIGMVENFNQALKEIGDVENWARSIELDMRTIATALEYVYKG------------QLQSAPS----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P78537-1", "uniprot_id": "BL1S1_HUMAN", "id": "P78537-1", "name": "Biogenesis of lysosome-related organelles complex 1 subunit 1", "aln": "MAPGSRGERSSFRSRRGPGVPSPQPDVTMLSRLLKEHQAKQNERKELQEKRRREAITAATCLTEALVDHLNVGVAQAYMNQRKLDHEVKTLQVQAAQFAKQTGQWIGMVENFNQALKEIGDVENWARSIELDMRTIATALEYVYKG------------QLQSAPS----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O55102-1", "uniprot_id": "BL1S1_MOUSE", "id": "O55102-1", "name": "Biogenesis of lysosome-related organelles complex 1 subunit 1", "aln": "----------------------------MLSRLLKEHQAKQNERKELQEKRRREAIAAATCLTEALVDHLNVGVAQAYMNQRKLDHEVKTLQVQAAQFAKQTGQWIGMVENFNQALKEIGDVENWARSIELDMRTIATALEYVYKG------------QLQSAPS----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A1Z9S1-1", "uniprot_id": "BL1S1_DROME", "id": "A1Z9S1-1", "name": "Biogenesis of lysosome-related organelles complex 1 subunit 1", "aln": "----------------------------MLTSMVKEHHKEQAKRKQEQEVRRKEAIEASNELTQSLVDTLNVGVAQAYLNQKRLDAEAKQLHLGATNFAKQTHQWLQLIDQFSTALKDLGDVENWARSIEGDMHTINQTLELAYKASRATQTSSGAGTSLEASTSASASANPSAT", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **: ::***: :* :**: ** **:*** *:. **::*** *********:**::** *.* *:: *::***** **: ::::*. ***::*********** **:** :** .**. .*:::.* ", "identical_positions": 70, "similar_positions": 37, "identity": "40.0%" }, { "cls_id": "homologset.agr.MGI:1195345", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LMU5-1", "uniprot_id": "F1LMU5_RAT", "id": "F1LMU5-1", "name": "Zinc finger and BTB domain-containing protein 14", "aln": "MEFFISMSETIKYNDDDHKTLFLKTLNEQRLEGEFCDIAIVVEDVKFRAHRCVLAACSTYFKKLFKKLEVDSSSVIEIDFLRSDIFEEVLNYMYTAKISVKKEDVNLMMSSGQILGIRFLDKLCSQKRDVSSPDESNGQSKSKYCLKLNRPIGDAADAQDDDVEEIGDQDDSPSDDTVEGTPPSQEDGKSPTTTLRVQEAILKELGSEEVRKVNCYGQEVESMETPESKDLGSQTPQALTFNDGMSEVKDEQTPGWTTAASDMKFEYLLYGHHREQIACQACGKTFSDEGRLRKHEKLHTADRPFVCEMCTKGFTTQAHLKEHLKIHTGYKPYSCEVCGKSFIRAPDLKKHERVHSNERPFACHMCDKAFKHKSHLKDHERRHRGEKPFVCGSCTKAFAKASDLKRHENNMHSERKQVTPSAIQSETEQLQAAAMAAEAEQQLETIACS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q08376-1", "uniprot_id": "ZBT14_MOUSE", "id": "Q08376-1", "name": "Zinc finger and BTB domain-containing protein 14", "aln": "MEFFISMSETIKYNDDDHKTLFLKTLNEQRLEGEFCDIAIVVEDVKFRAHRCVLAACSTYFKKLFKKLEVDSSSVIEIDFLRSDIFEEVLNYMYTAKISVKKEDVNLMMSSGQILGIRFLDKLCSQKRDVSSPDESNGQSKSKYCLKLNRPIGDAADAQDDDVEEIGDQDDSPSDDTVEGTPPSQEDGKSPTTTLRVQEAILKELGSEEVRKVNCYGQEVESMETPESKDLGSQTPQALTFNDGMSEVKDEQTPGWTTAASDMKFEYLLYGHHREQIACQACGKTFSDEGRLRKHEKLHTADRPFVCEMCTKGFTTQAHLKEHLKIHTGYKPYSCEVCGKSFIRAPDLKKHERVHSNERPFACHMCDKAFKHKSHLKDHERRHRGEKPFVCGSCTKAFAKASDLKRHENNMHSERKQVTPSAIQSETEQLQAAAMAAEAEQQLETIACS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43829-1", "uniprot_id": "ZBT14_HUMAN", "id": "O43829-1", "name": "Zinc finger and BTB domain-containing protein 14", "aln": "MEFFISMSETIKYNDDDHKTLFLKTLNEQRLEGEFCDIAIVVEDVKFRAHRCVLAACSTYFKKLFKKLEVDSSSVIEIDFLRSDIFEEVLNYMYTAKISVKKEDVNLMMSSGQILGIRFLDKLCSQKRDVSSPDENNGQSKSKYCLKINRPIGDAADTQDDDVEEIGDQDDSPSDDTVEGTPPSQEDGKSPTTTLRVQEAILKELGSEEVRKVNCYGQEVESMETPESKDLGSQTPQALTFNDGMSEVKDEQTPGWTTAASDMKFEYLLYGHHREQIACQACGKTFSDEGRLRKHEKLHTADRPFVCEMCTKGFTTQAHLKEHLKIHTGYKPYSCEVCGKSFIRAPDLKKHERVHSNERPFACHMCDKAFKHKSHLKDHERRHRGEKPFVCGSCTKAFAKASDLKRHENNMHSERKQVTPSAIQSETEQLQAAAMAAEAEQQLETIACS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***************************************************************************************************************************************.***********:*********:***************************************************************************************************************************************************************************************************************************************************************************************************", "identical_positions": 446, "similar_positions": 3, "identity": "99.33%" }, { "cls_id": "homologset.agr.MGI:1195456", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P29315-1", "uniprot_id": "RINI_RAT", "id": "P29315-1", "name": "Ribonuclease inhibitor", "aln": "-----MSLDIQCEQLSDARWTELLPLIQQYQVVRLDDCGLTEVRCKDIRSAIQANPALTELSLRTNELGDAGVGLVLQGLQNPTCKIQKLSLQNCSLTEAGCGVLPDVLRSLSTLRELHLNDNPLGDEGLKLLCEGLRDPQCRLEKLQLEYCNLTATSCEPLASVLRVKPDFKELVLSNNDFHEAGIHTLCQGLKDSACQLESLKLENCGITSANCKDLCDVVASKASLQELDLGSNKLGNTGIAALCSGLLLPSCRLRTLWLWDCDVTAEGCKDLCRVLRAKQSLKELSLAGNELKDEGAQLLCESLLEPGCQLESLWVKTCSLTAASCPHFCSVLTKNRSLFELQMSSNPLGDSGVVELCKALGYPDTVLRVLWLGDCDVTDSGCSSLATVLLANRSLRELDLSNNCMGDNGVLQLLESLKQPSCILQQLVLYDIYWTDEVEDQLRALEEERPSLRIIS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91VI7-1", "uniprot_id": "RINI_MOUSE", "id": "Q91VI7-1", "name": "Ribonuclease inhibitor", "aln": "-----MSLDIQCEQLSDARWTELLPLIQQYEVVRLDDCGLTEVRCKDISSAVQANPALTELSLRTNELGDGGVGLVLQGLQNPTCKIQKLSLQNCGLTEAGCGILPGMLRSLSTLRELHLNDNPMGDAGLKLLCEGLQDPQCRLEKLQLEYCNLTATSCEPLASVLRVKADFKELVLSNNDLHEPGVRILCQGLKDSACQLESLKLENCGITAANCKDLCDVVASKASLQELDLSSNKLGNAGIAALCPGLLLPSCKLRTLWLWECDITAEGCKDLCRVLRAKQSLKELSLASNELKDEGARLLCESLLEPGCQLESLWIKTCSLTAASCPYFCSVLTKSRSLLELQMSSNPLGDEGVQELCKALSQPDTVLRELWLGDCDVTNSGCSSLANVLLANRSLRELDLSNNCMGGPGVLQLLESLKQPSCTLQQLVLYDIYWTNEVEEQLRALEEERPSLRIIS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P13489-1", "uniprot_id": "RINI_HUMAN", "id": "P13489-1", "name": "Ribonuclease inhibitor", "aln": "MSLDIQSLDIQCEELSDARWAELLPLLQQCQVVRLDDCGLTEARCKDISSALRVNPALAELNLRSNELGDVGVHCVLQGLQTPSCKIQKLSLQNCCLTGAGCGVLSSTLRTLPTLQELHLSDNLLGDAGLQLLCEGLLDPQCRLEKLQLEYCSLSAASCEPLASVLRAKPDFKELTVSNNDINEAGVRVLCQGLKDSPCQLEALKLESCGVTSDNCRDLCGIVASKASLRELALGSNKLGDVGMAELCPGLLHPSSRLRTLWIWECGITAKGCGDLCRVLRAKESLKELSLAGNELGDEGARLLCETLLEPGCQLESLWVKSCSFTAACCSHFSSVLAQNRFLLELQISNNRLEDAGVRELCQGLGQPGSVLRVLWLADCDVSDSSCSSLAATLLANHSLRELDLSNNCLGDAGILQLVESVRQPGCLLEQLVLYDIYWSEEMEDRLQALEKDKPSLRVIS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *******:******:*****:** :***********.***** **::.****:**.**:***** ** ******.*:*********** ** ****:*.. **:*.**:****.** :** **:****** **************.*:*:**********.*.*****.:****::*.*:: ********.****:****.**:*: **:***.:*******:** *.*****:.*:* **.*** **.:*****:*:*.:**:** *********:********.*** ****:****:************:*:**:***.*.:*.***::.* *:***:*.* * * ** ***:.*. *.:*** ***.****::*.***** .****:***********:*. *:***:**::**.* *:*********::*:*::*:***:::****:**", "identical_positions": 326, "similar_positions": 101, "identity": "70.72%" }, { "cls_id": "homologset.agr.MGI:1195458", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZD23-1", "uniprot_id": "D3ZD23_RAT", "id": "D3ZD23-1", "name": "", "aln": "--------MADKLTRIAIVNHDKCKPKKCRQECKKSCPVVRMGKLCIEVTPQSKIAWISETLCIGCGICIKKCPFGALSIVNLPSNLEKETTHRYCANAFKLHRLPIPRPGEVLGLVGTNGIGKSTALKILAGKQKPNLGKYDDPPDWQEILTYFRGSELQNYFTKILEDDLKAIIKPQYVDQIPKAAKG---TVGSILDRKDET--KTQAVVCQQLDLTHLKERNVEDLSGGELQRFACAVVCIQKADIFMFDEPSSYLDVKQRLKAAITIRSLINPDRYIIVVEHDLSVLDYLSDFICCLYGVPSAYGVVTMPFSVREGINIFLDGYVPTENLRFRDASLVFKVAETANEEEVKKMC-MYKYPGMKKKMGEFELAIVAGEFTDSEIMVMLGENGTGKTTFIRMLAGRLKPDEGGEVPVLNVSYKPQKISPKSTGSVRQLLHEKIRDAYTHPQFVTDVMKPLQIENIIDQEVQTLSGGELQRVALALCLGKPADVYLIDEPSAYLDSEQRLMAARVVKR-----------------------------------------PQTLLAGMNKFLSQLEITFRRDPNNYRPRINKLNSIKDVEQKKSGNYFFLDD----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P61221-1", "uniprot_id": "ABCE1_HUMAN", "id": "P61221-1", "name": "ATP-binding cassette sub-family E member 1", "aln": "--------MADKLTRIAIVNHDKCKPKKCRQECKKSCPVVRMGKLCIEVTPQSKIAWISETLCIGCGICIKKCPFGALSIVNLPSNLEKETTHRYCANAFKLHRLPIPRPGEVLGLVGTNGIGKSTALKILAGKQKPNLGKYDDPPDWQEILTYFRGSELQNYFTKILEDDLKAIIKPQYVDQIPKAAKG---TVGSILDRKDET--KTQAIVCQQLDLTHLKERNVEDLSGGELQRFACAVVCIQKADIFMFDEPSSYLDVKQRLKAAITIRSLINPDRYIIVVEHDLSVLDYLSDFICCLYGVPSAYGVVTMPFSVREGINIFLDGYVPTENLRFRDASLVFKVAETANEEEVKKMC-MYKYPGMKKKMGEFELAIVAGEFTDSEIMVMLGENGTGKTTFIRMLAGRLKPDEGGEVPVLNVSYKPQKISPKSTGSVRQLLHEKIRDAYTHPQFVTDVMKPLQIENIIDQEVQTLSGGELQRVALALCLGKPADVYLIDEPSAYLDSEQRLMAARVVKRFILHAKKTAFVVEHDFIMATYLADRVIVFDGVPSKNTVANSPQTLLAGMNKFLSQLEITFRRDPNNYRPRINKLNSIKDVEQKKSGNYFFLDD----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P61222-1", "uniprot_id": "ABCE1_MOUSE", "id": "P61222-1", "name": "ATP-binding cassette sub-family E member 1", "aln": "--------MADKLTRIAIVNHDKCKPKKCRQECKKSCPVVRMGKLCIEVTPQSKIAWISETLCIGCGICIKKCPFGALSIVNLPSNLEKETTHRYCANAFKLHRLPIPRPGEVLGLVGTNGIGKSTALKILAGKQKPNLGKYDDPPDWQEILTYFRGSELQNYFTKILEDDLKAIIKPQYVDQIPKAAKG---TVGSILDRKDET--KTQAIVCQQLDLTHLKERNVEDLSGGELQRFACAVVCIQKADIFMFDEPSSYLDVKQRLKAAITIRSLINPDRYIIVVEHDLSVLDYLSDFICCLYGVPSAYGVVTMPFSVREGINIFLDGYVPTENLRFRDASLVFKVAETANEEEVKKMC-MYKYPGMKKKMGEFELAIVAGEFTDSEIMVMLGENGTGKTTFIRMLAGRLKPDEGGEVPVLNVSYKPQKISPKSTGSVRQLLHEKIRDAYTHPQFVTDVMKPLQIENIIDQEVQTLSGGELQRVALALCLGKPADVYLIDEPSAYLDSEQRLMAARVVKRFILHAKKTAFVVEHDFIMATYLADRVIVFDGVPSKNTVANSPQTLLAGMNKFLSQLEITFRRDPNNYRPRINKLNSIKDVEQKKSGNYFFLDD----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9VSS1-1", "uniprot_id": "ABCE1_DROME", "id": "Q9VSS1-1", "name": "Protein Pixie", "aln": "MSRRKENEEVDKQTRIAIVSDDKCKPKRCRQECKKTCPVVRMGKLCIEVTPTSKIASLSEELCIGCGICVKKCPFEAITIINLPSNLEKHTTHRYSKNSFKLHRLPIPRPGEVLGLVGQNGIGKSTALKILAGKQKPNLGKYANPPDWTEILSYFRGSELQNYFTKILEDNLKALVKPQYVDQIPKAVRG---AVGDLLDKKDER--ELQTKICEMLDLSHIRDREIAQLSGGELQRFAIAMVCIQNADIFMFDEPSSYLDVKQRLNAALTIRSLLHPTKFIIVVEHDLSVLDYLSDFICCLYGVPGCYGVVTMPFSVREGINIFLDGFVPTENMRFRTESLTFKVSESATEEEIKRMN-HYVYPAMVKTLGKFELTVEKGHFSDSEILVLLGENGTGKTTFIRMLAGNLQPDGEVELPMLNISYKPQKISPKFQNHVRHLLHDKIRDAYVHPQFIADVMKPMKIEEIMDQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRYILHAKKTGFVVEHDFIMATYLADRVIVIEGQPSVKTTAFSPQSLLNGMNRFLELLGITFRRDPNNFRPRINKNNSVKDTEQKRSGQFFFLEDEACN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q03195-1", "uniprot_id": "RLI1_YEAST", "id": "Q03195-1", "name": "Translation initiation factor RLI1", "aln": "--------MSDKNSRIAIVSADKCKPKKCRQECKRSCPVVKTGKLCIEVTPTSKIAFISEILCIGCGICVKKCPFDAIQIINLPTNLEAHVTHRYSANSFKLHRLPTPRPGQVLGLVGTNGIGKSTALKILAGKQKPNLGRFDDPPEWQEIIKYFRGSELQNYFTKMLEDDIKAIIKPQYVDNIPRAIKGPVQKVGELLKLRMEKSPEDVKRYIKILQLENVLKRDIEKLSGGELQRFAIGMSCVQEADVYMFDEPSSYLDVKQRLNAAQIIRSLLAPTKYVICVEHDLSVLDYLSDFVCIIYGVPSVYGVVTLPASVREGINIFLDGHIPAENLRFRTEALQFRIADATEDLQNDSASRAFSYPSLKKTQGDFVLNVEEGEFSDSEILVMMGENGTGKTTLIKLLAGALKPDEGQDIPKLNVSMKPQKIAPKFPGTVRQLFFKKIRGQFLNPQFQTDVVKPLRIDDIIDQEVQHLSGGELQRVAIVLALGIPADIYLIDEPSAYLDSEQRIICSKVIRRFILHNKKTAFIVEHDFIMATYLADKVIVFEGIPSKNAHARAPESLLTGCNRFLKNLNVTFRRDPNSFRPRINKLDSQMDKEQKSSGNYFFLDNTGI-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** :*****. ******:******::****: ********* **** :** ********:***** *: *:***:*** ..****. *:******* ****:****** *********************:: :**:* **:.*************:***::**::******:**:* :* **.:*. : * : : *:* :: .*:: .********** .: *:*:**::***************:** ****: * :::* **************:* :****. *****:* ************.:*:**:*** :* *:::::: : : . : **.: *. *.* * : *.*:****:*::*********:*::*** *:** ::* **:* *****:** . **:*:..***. : :*** :**:**::*::*:***** **********:.*.** ***:***************::.::*::* *::** * *:**. * :*******.:****** :* * *** **::***:: ", "identical_positions": 348, "similar_positions": 129, "identity": "56.4%" }, { "cls_id": "homologset.agr.MGI:1195461", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JJM9-1", "uniprot_id": "SEPT5_RAT", "id": "Q9JJM9-1", "name": "Septin-5", "aln": "------------------------------------------------MSTGLRYKSKLATP----------EDKQD-----------------IDKQYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVHSLFLTDLYKDRKLLSAEERIN---------------------QTVEILKHTVDIEEKGVKLKLTIVDTPGFGDAVNNFE-CWKPITDYVDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRPVDVGFMKALHEKVNIVPLIAKADCLVPSEIRKLKDRIREEIDKFGIHVYQFPECDSDEDEDFKQQDRELKESAPFAVIGSNTVVEAK-GQRVRGRLYPWGIVEVENQAHCDFVKLRNMLIRTHMHDLKDVTCDVHYENYRAHCIQQMTS--------------------KLTQDS--RMESPIPILPLPTPDSETEKLIRMKDEELRRMQEMLQKMKQRMQDQ--------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z2Q6-1", "uniprot_id": "SEPT5_MOUSE", "id": "Q9Z2Q6-1", "name": "Septin-5", "aln": "------------------------------------------------MSTGLRYKSKLATP----------EDKQD-----------------IDKQYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVHSLFLTDLYKDRKLLSAEERIN---------------------QTVEILKHTVDIEEKGVKLKLTIVDTPGFGDAVNNSE-CWKPITDYVDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRPVDVGFMKALHEKVNIVPLIAKADCLVPSEIRKLKDRIREEIDKFGIHVYQFPECDSDEDEDFKQQDRELKESAPFAVIGSNTVVEAK-GQRVRGRLYPWGIVEVENQAHCDFVKLRNMLIRTHMHDLKDVTCDVHYENYRAHCIQQMTS--------------------KLTQDS--RMESPIPILPLPTPDAETEKLIRMKDEELRRMQEMLQKMKQQMQDQ--------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99719-1", "uniprot_id": "SEPT5_HUMAN", "id": "Q99719-1", "name": "Septin-5", "aln": "------------------------------------------------MSTGLRYKSKLATP----------EDKQD-----------------IDKQYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVHSLFLTDLYKDRKLLSAEERIS---------------------QTVEILKHTVDIEEKGVKLKLTIVDTPGFGDAVNNTE-CWKPITDYVDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRPVDVGFMKALHEKVNIVPLIAKADCLVPSEIRKLKERIREEIDKFGIHVYQFPECDSDEDEDFKQQDRELKESAPFAVIGSNTVVEAK-GQRVRGRLYPWGIVEVENQAHCDFVKLRNMLIRTHMHDLKDVTCDVHYENYRAHCIQQMTS--------------------KLTQDS--RMESPIPILPLPTPDAETEKLIRMKDEELRRMQEMLQRMKQQMQDQ--------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PTI3-1", "uniprot_id": "A0A8M9PTI3_DANRE", "id": "A0A8M9PTI3-1", "name": "Septin", "aln": "------------------------------------------------MTSSARYKSRTVKS----------EDGE-------------------EKEYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLINSLFLTDLYKDRKLLNAEERIS---------------------QTVEIIKHTVDIEEKGVKLKLTIVDTPGFGDAVNNTE-SWRTITDYIEQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRPVDVEFMKALQDKVNIVPLISKADCLTPAEMRKMKDRVREEIEKFGIKVYQFPDCDSDEDEELKQQDRELKESTPFAVIGSNTIVEVK-GQRVRGRLYPWGIVEVENQSHCDFVKLRNMLIRSHMHDLKDITCDAHYENYRAQCIQQMTSS-------------------KLTQDN--RVESPIPILPLSTPDVETEKLIKMKDEELRRMQEMLQKMQQQMHEQD----L--------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q0KHR7-1", "uniprot_id": "Q0KHR7_DROME", "id": "Q0KHR7-1", "name": "Septin", "aln": "---------MKHQPPPPPLPLSQPPTMGATAAG----GVASVIST-MNGSSSSGIEAVKCRPPIYP---KPKTPSFD-----------------KDRDYIGFATLPEQVHRKSVKRGFEFTLMVVGESGLGKSTLINSLFLGDLYKNRQMPNVEERIE---------------------KTTKVEKKTMDIEERGVRLRLTVVDTPGFGDAINCED-SWRVCTQYIDEQFRQYFTDESGLNRRNIQDNRVHCCLYFVPPWGHSLRQMDLDLIRRLHRKVNIVLVIGKADCLNKQEVRKLKERILQDLEDNHIQLYQFPECDSDEDDDFKQQDRELKASIPFAVVGSNTILEVA-GKKVRGRQYPWGVVNVEDPEHSDFIKLRTFLISTHMQDLKDTTQDVHYENFRAQCISQISQH-------------------ALRERGKLKRDSISSTNGFDAAISETDRLLLQKDEEIRRMQDMLTQMQEKLKQTH----LMEMKKNDSVIDV--------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32457-1", "uniprot_id": "CDC3_YEAST", "id": "P32457-1", "name": "Cell division control protein 3", "aln": "MSLKEEQVSIKQDPEQEERQHDQFNDVQIKQESQDHDGVDSQYTNGTQNDDSERFEAAESDVKVEPGLGMGITSSQSEKGQVLPDQPEIKFIRRQINGYVGFANLPKQWHRRSIKNGFSFNLLCVGPDGIGKTTLMKTLFNNDDIEANLVKDYEEELANDQEEEEGQGEGHENQSQEQRHKVKIKSYESVIEENGVKLNLNVIDTEGFGDFLNNDQKSWDPIIKEIDSRFDQYLDAENKINRHSINDKRIHACLYFIEPTGHYLKPLDLKFMQSVYEKCNLIPVIAKSDILTDEEILSFKKTIMNQLIQSNIELFKPPIYSNDDAENSHLSER-LFSSLPYAVIGSNDIVENYSGNQVRGRSYPWGVIEVDNDNHSDFNLLKNLLIKQFMEELKERTSKILYENYRSSKLAKLGIKQDNSVFKEFDPISKQQEEKTLHEAKLAKLEIEMKTVFQQKVSEKEKKLQKSETELFARHKEMKEKLTKQLKALEDKKKQLELSINSASPNVNHSPVPTKKKGFLR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :: . *:***.**:* **:*:*.**.*.*: .* .*:**:**:::** * : . : . **.: :..:: . ***.**:*.*.::** **** :* : .* . ::.:* **: *. :**:.*:*:*:*.****: * ** *: :*: ::: : * *:: :*.*:* * *: .:*. : ::: . *.::: * ..*: :: : .:* * * *:**:*** ::* *::**** ****:::*:: *.** *:.:** .*.:**: * . ***:*: : :: * : : : : .:* : * : * ::* :: :::: ", "identical_positions": 110, "similar_positions": 130, "identity": "21.11%" }, { "cls_id": "homologset.agr.MGI:1195462", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O08842-1", "uniprot_id": "GFRA2_MOUSE", "id": "O08842-1", "name": "GDNF family receptor alpha-2", "aln": "------------MILAN-----AFCLFFFLDETLRSLASPSSPQGSELHGWRPQVDCVRANELCAAESNCSSRYRTLRQCLAGRDRNTMLANKECQAALEVLQESPLYDCRCKRGMKKELQCLQIYWSIHLGLTEGEEFYEASPYEPVT-SRLSDIFRLASIFSGTG-----ADPVVSAKS---NHCLDAAKACNLNDNCKKLRSSYISICNREIS---------PTERCNRRKCHKALRQFFDRVPSEYTYRMLFCSCQDQACAERRRQTILPSCSYEDKEKPNCLDLRSLCRTDHLCRSRLADFHANCRASYRTITSCPADNYQACLGSYAGMIGFDMTPNYVDSNPTGIVVSPWCNCRGSGNMEEECEKFLKDFTENPCLRNAIQAFGNGTDVNMSPKGPTFSATQAPRVEKTPSLPDDLSDSTSLGTSVITTCTSIQEQGLKANNSKELSMCFTELTTNISPGSKKVIKLYSGSC--RARLSTALTALPLLMVTLAQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O35977-1", "uniprot_id": "O35977_RAT", "id": "O35977-1", "name": "GDNF family receptor alpha-2", "aln": "------------MILAN-----AFCLFFFLDETLRSLASPSSLQGSELHGWRPQVDCVRANELCAAESNCSSRYRTLRQCLAGRDRNTMLANKECQAALEVLQESPLYDCRCKRGMKKELQCLQIYWSIHLGLTEGEEFYEASPYEPVT-SRLSDIFRLASIFSGTG-----TDPAVSTKS---NHCLDAAKACNLNDNCKKLRSSYISICNREIS---------PTERCNRRKCHKALRQFFDRVPSEYTYRMLFCSCQDQACAERRRQTILPSCSYEDKEKPNCLDLRSLCRTDHLCRSRLADFHANCRASYRTITSCPADNYQACLGSYAGMIGFDMTPNYVDSNPTGIVVSPWCNCRGSGNMEEECEKFLRDFTENPCLRNAIQAFGNGTDVNMSPKGPSLPATQAPRVEKTPSLPDDLSDSTSLGTSVITTCTSIQEQGLKANNSKELSMCFTELTTNISPGSKKVIKLNSGSS--RARLSAALTALPLLMLTLAL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O00451-1", "uniprot_id": "GFRA2_HUMAN", "id": "O00451-1", "name": "GDNF family receptor alpha-2", "aln": "------------MILAN-----VFCLFFFLDETLRSLASPSSLQGPELHGWRPPVDCVRANELCAAESNCSSRYRTLRQCLAGRDRNTMLANKECQAALEVLQESPLYDCRCKRGMKKELQCLQIYWSIHLGLTEGEEFYEASPYEPVT-SRLSDIFRLASIFSGTG-----ADPVVSAKS---NHCLDAAKACNLNDNCKKLRSSYISICNREIS---------PTERCNRRKCHKALRQFFDRVPSEYTYRMLFCSCQDQACAERRRQTILPSCSYEDKEKPNCLDLRGVCRTDHLCRSRLADFHANCRASYQTVTSCPADNYQACLGSYAGMIGFDMTPNYVDSSPTGIVVSPWCSCRGSGNMEEECEKFLRDFTENPCLRNAIQAFGNGTDVNVSPKGPSFQATQAPRVEKTPSLPDDLSDSTSLGTSVITTCTSVQEQGLKANNSKELSMCFTELTTNIIPGSNKVIKPNSGPS--RARPSAALTVLSVLMLKLAL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0S6A6-1", "uniprot_id": "B0S6A6_DANRE", "id": "B0S6A6-1", "name": "GDNF family receptor alpha-2", "aln": "MTARAAPFYARGFLSRNRNMYIYIGFLLFLDELVFSMSGSSSLSES---GNQDSMDCLKATEKCNQDQKCSHRFRIMRQCLAGKDRNTMLANRDCQVALEVLQEMALFDCRCKRGMKKEMQCLQSYWSINIGLTEGEDFYEPSPYEPMTPHRHSDAFRLASIISGMHSGTSKGQPHCTDPSRPCNPCLDATKACNLNENCKRQRSNYISTCTRAQTQGQQPSQTQTQEGCNRKRCHKALRQFFERVDTQYSYGLLFCACKDQACAERRRQTIVPSCSYQDKNKPNCLQLRNTCRLDVHCRSRLADFHTNCQMTPHSISSCLNDDYQACLASYTRLIGTDMTPNYLDSGHSNFTISPWCTCKGSGNLEEECEKFLQDFRENTCLRNAIQAFGYGSLPKPDPQ--PTTGSVKPDLEPTATVAKTTME-PGEDPCIISPCSNLNELDCYPSKDYNCESAEMKLSKPESPLNTRVEDPRNTSPGVKALTEAMMQSLLFALVTLVM", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: * : :::**** : *::..** . . * : :**::*.* * :.:** *:* :******:********::**.******* .*:***********:**** ****::******:***.*****:* * ** ******:** :* : * * ****:******:***: **.*** *.* : . * ***::*********:** ::*:* :***:*:************:*****:**:*****:**. ** * *********:**: : ::::** *:*****.**: :** ******:**. :.:.:****.*:****:********:** **.********** *: : .*: . .: * :* *.::.. : .. ...:*:.*:.::* . ..:. : . . :*:. * ..:* . . . :* .: : * . ::.*. ", "identical_positions": 236, "similar_positions": 134, "identity": "47.11%" }, { "cls_id": "homologset.agr.MGI:1195463", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O19477-1", "uniprot_id": "HMR1_RAT", "id": "O19477-1", "name": "Major histocompatibility complex class I-related protein 1", "aln": "--------MMFLLPFLTVFLAKQSHTRTHSLRYFRLAISDPGPGVPEFISVGYVDSHPITTYDSVTRQKEPRAPWMAENLAPDHWERYTQLLRGWQRTFQTELRHLQRHYNHSG-LHTYQRMIGCELLED-GSTTGFLQYAYDGQDFIVFDKDTLSWLAMDNVAHITKRAWEANLHELQYQKNWLEEECIAWLKRFLEYGSDALERTEHPVVRTTRKETFPGITTLFCRAHGFYPPEISMIWKKNGEEIVQEVDYGGVLPSGDGTYQMWVSVDLDPQ--TKDIYSCHVEHCGLQMVLEAPQ----ESGNTLLVANTISGTIILIIVLAGVGALIWRRRSREPKEVMYQPTQVNEGSSPS----------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8HWB0-1", "uniprot_id": "HMR1_MOUSE", "id": "Q8HWB0-1", "name": "Major histocompatibility complex class I-related protein 1", "aln": "--------MMLLLPLLAVFLVKRSHTRTHSLRYFRLAVSDPGPVVPEFISVGYVDSHPITTYDSVTRQKEPKAPWMAENLAPDHWERYTQLLRGWQQTFKAELRHLQRHYNHSG-LHTYQRMIGCELLED-GSTTGFLQYAYDGQDFIIFNKDTLSWLAMDYVAHITKQAWEANLHELQYQKNWLEEECIAWLKRFLEYGRDTLERTEHPVVRTTRKETFPGITTFFCRAHGFYPPEISMTWMKNGEEIAQEVDYGGVLPSGDGTYQTWLSVNLDPQ--SNDVYSCHVEHCGRQMVLEAPR----ESGDILRVS-TISGTTILIIALAGVGVLIWRR-SQELKEVMYQPTQVNEGSSPS----------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q95460-1", "uniprot_id": "HMR1_HUMAN", "id": "Q95460-1", "name": "Major histocompatibility complex class I-related protein 1", "aln": "----MGELMAFLLPLIIVLMVKHSDSRTHSLRYFRLGVSDPIHGVPEFISVGYVDSHPITTYDSVTRQKEPRAPWMAENLAPDHWERYTQLLRGWQQMFKVELKRLQRHYNHSG-SHTYQRMIGCELLED-GSTTGFLQYAYDGQDFLIFNKDTLSWLAVDNVAHTIKQAWEANQHELLYQKNWLEEECIAWLKRFLEYGKDTLQRTEPPLVRVNRKETFPGVTALFCKAHGFYPPEIYMTWMKNGEEIVQEIDYGDILPSGDGTYQAWASIELDPQ--SSNLYSCHVEHCGVHMVLQVPQ----ESETIPLVMKAVSGSIVLVIVLAGVGVLVWRRRPREQNGAIYLPTPDR----------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58HZ21-1", "uniprot_id": "A0AC58HZ21_DANRE", "id": "A0AC58HZ21-1", "name": "", "aln": "MADRITQMQKMEYILLLVVCLPYVDGATHTWNAYYTATTG-LSQFPEFVAQNLIDGQLMGYFDSKTNCFKSQFQWMEDKLGTAYDEQQTNILQRHTAKFKNNIKVAIERFNQTQGVHTLQEIYGCEWDDQTGNLNAFRQYGYNGEDFLTLDFMEMRWITPVQQAMITTQKWNNDRGFIESDMNYFRSECIEWLQKYLEYGKSSLMKTVSPQVSVLQKYYFS---PVVCHATGFYPSGIKISWQKNGQDHDEDVELGELLPNADGTFQKRSTLNVKPEEWKNSKFSCVVEHQGERILTEDEIRTNNPSATIGIIIGIVLSAVLLLFIAVAGFVVYWKKKGFKPVPANPSDSVAEKTKSQTSVNSDNDSGCGSGSDSVSHKSSDSTSDISSVCSDNSSDSTTALLPENSDKNSGCDSGSDSVSHKSSDSTSDISSVCSDNSSDSTTALF", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: *. . **: . : . :. .***:: . :*.: : :** *. :.: ** ::*.. : *: *::*: *: ::: .::*:: ** *.: *** :: *. ..* **.*:*:**: :: : *:: * .: *: : : : *::..*** **:::**** .:* :* * * . :* *. ...*:* ****. * : * ***:: :::: * :**..***:* ::::.*: ... :** *** * ::: : * : : .: :*:: .. .: *:: : . : . ", "identical_positions": 79, "similar_positions": 124, "identity": "17.67%" }, { "cls_id": "homologset.agr.MGI:1195966", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9UQB3-1", "uniprot_id": "CTND2_HUMAN", "id": "Q9UQB3-1", "name": "Catenin delta-2", "aln": "MFARKPPGAAPLGAMPVPDQPSSASEKTSSLSPGLNTSNGDGSETETTSAILASVKEQELQFERLTRELEAERQIVASQLERCKLGSETG-SMSSMSSAEEQFQWQSQDGQKDIEDELTTGLELVDSCIRSLQESGILDPQDYSTGERPSLLSQSALQLNSKPEGSFQYPASYHSNQTLALGETT------PSQLPARGT-QARATGQSFSQGTTSRAGHLAGPEPAPPPPPPPREPFAPSLGSAFHLPDAPPAAAAAALYYSSSTLPAPPRGGSPL----AAPQGGSPTKLQRGGSAPEGATYA-APRGSS------PKQSPSRLAKSYSTSSPINIVVSS-AGLSPIRVTSPPTVQSTISSSPIHQLSSTIG--TYATLSPTKRLVHASEQYSKHSQELYATATLQRPGSLAAGSRASYSSQHGHLGPELRALQSPEHHIDPIYEDRVYQKPPMRSLSQSQG----------------------DPLPPAHTGTYR-TSTAPSSPGVDSVPLQRTGSQHGPQNAAAATFQRASYAAGP---ASNYADPYRQLQYCPSVESPYSKSGPALPPEGTLARSPSIDSIQKDPR-------------------EFGWRDPELPEVIQMLQHQFPSVQSNAAAYLQHLCFGDNKIKAEIRRQGGIQLLVDLLDHRMTEVHRSACGALRNLVYGKANDDNKIALKNCGGIPALVRLLRKTTDLEIRELVTGVLWNLSSCDALKMPIIQDALAVLTNAVIIPHSGWENSPLQDDRKIQLHSSQVLRNATGCLRNVSSAGEEARRRMRECDGLTDALLYVIQSALGSSEIDSKTVENCVCILRNLSYRLAAETSQGQHMGTDELDGLLCGEANGKDAESSGCWGKKKKKKKSQ--DQWDGVGPLPDCAEP-------PKGIQMLWHPSIVKPYLTLLSECSNPDTLEGAAGALQNLAAGSWK-------------------------WSVYIRAAVRKEKGLPILVELLRIDNDRVVCAVATALRNMALDVRNKELIGKYAMRDLVHRLPGGNNSNNT--------ASKAMSDDTVTAVCCTLHEVITKNMENAKALRDAGGIEKLVGISKSKGDKHSPKVVKAASQVLNSMWQYRDLRSLYKKDGWSQYHFVASSSTIERDRQRPYSSSRTPSISPVRVSPNNRSASAPASPREMISLKERKTDYECTGSNATYHGAKGEHTSRKDAMTAQN-TGISTLYRNSYGAPAEDIKHNQVSAQPVPQEPSRKDYETYQPFQNST-RNYDESFFEDQVHHR-PPASEYTMHLGLKSTGNYVDFYSAARPYSELNYETSHYPASPDSWV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O35927-1", "uniprot_id": "CTND2_MOUSE", "id": "O35927-1", "name": "Catenin delta-2", "aln": "MFARKQSGAAPFGAMPVPDQPPSASEKNSSLSPGLNTSNGDGSETETTSAILASVKEQELQFERLTRELEAERQIVASQLERCKLGSETG-SMSSISSAGEQFHWQTQDGQKDIEDELTTGLELVDSCIRSLQESGILDPQDYSTSERPSLLSQSALQLNSKPEGSFQYPASYHSNQTLALGDTA------PSQLPARST-QARAAGQSFSQGTTGRAGHLAGSEPAPPPPPP-REPFAPSLGSAFHLPDAPP--AAAALYYSSSTLPAPPRGGSPL----TTTQGGSPTKLQRGGSAPEGAAYA-APRGSS------PKQSPSRLAKSYSTSSPINIVVSS-AGLSPIRVTSPPTVQSTISSSPIHQLSSTIG--TYATLSPTKRLVHASEQYSKHSQELYATATLQRPGSLAAGSRASYSSQHGHLAPELRALQSPEHHIDPIYEDRVYQKPPMRSLSQSQG----------------------DPLPPAHTGTFR-TSTAPSSPGVDSVPLQRTGSQHGPQNAAAATFQRASYAAGP---ASNYADPYRQLQYCASVDSPYSKSGPALPPEGTLARSPSIDSIQKDPR-------------------EFGWRDPELPEVIQMLQHQFPSVQSNAAAYLQHLCFGDNKIKAEIRRQGGIQLLVDLLDHRMTEVHRSACGALRNLVYGKANDDNKIALKNCGGIPALVRLLRKTTDLEIRELVTGVLWNLSSCDALKMPIIQDALAVLTNAVIIPHSGWENSPLQDDRKIQLHSSQVLRNATGCLRNVSSAGEEARRRMRECDGLTDALLYVIQSALGSSEIDSKTVENCVCILRNLSYRLAAETSQGQHMGTDELDGLLCGETNGKDTESSGCWGKKKKKKKSQ--DQWDGVGPLPDCAEP-------PKGIQMLWHPSIVKPYLTLLSECSNPDTLEGAAGALQNLAAGSWKGWAEDVAGMAYALRSLPEGAPCLPQWSVYIRAAVRKEKGLPILVELLRIDNDRVVCAVATALRNMALDVRNKELIGKYAMRDLVHRLPGGNNSNNS--------GSKAMSDDTVTAVCCTLHEVITKNMENAKALRDAGGIEKLVGISKSKGDKHSPKVVKAASQVLNSMWQYRDLRSLYKKDGWSQYHFVASSSTIERDRQRPYSSSRTPSISPVRVSPNNRSASAPASPREMISLKERKTDYESAGNNATYHGTKGEHTSRKDTMTAQN-TGVSTLYRNSYGAPAEDIKQNQVSTQPVPQEPSRKDYETYQPFPNST-RNYDESFFEDQVHHR-PPASEYTMHLGLKSTGNYVDFYSAARPYSELNYETSHYPASPDSWV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O35116-1", "uniprot_id": "CTND2_RAT", "id": "O35116-1", "name": "Catenin delta-2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FPSVQSNAAAYLQHLCFGDNKIKAEIRRQGGIQLLVDLLDHRMTEVHRSACGALRNLVYGKANDDNKIALKNCGGIPALVRLLRKTTDLEIRELVTGVLWNLSSCDALKMPIIQDALAVLTNAVIIPHSGWENSPLQDDRKIQLHSSQVLRNATGCLRNVSSAGEEARRRMRECDGLTDALLYVIQSALGSSEIDSKTVENCVCILRNLSYRLAAETSQGQHMGTDELDGLLCGEANGKDAESSGCWGKKKKKKKSQ--DQWDGVG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0AB13A7D4-1", "uniprot_id": "A0AB13A7D4_DANRE", "id": "A0AB13A7D4-1", "name": "", "aln": "--------------MPVPDQP-SGTENSSMLSPVLNASNGDGSETETTSAILASVKEQELQFERLTRELEAERQIVATQLERCKLGSETG-SMSSISSADEKFRWNNQDGQKDIEEELTTGLELVDSCIRSLQESGILDSQEFTAGERPGILSQSALQLNNQ-EGTFPYPVSYHSNQTLALGDLS------ASQ-PPRSG-QVGGALHSYNQVTSNRVAQLAARETAAR--AHSRDSYAQSHGSAFHMPDDQP---TVPVNYSCATLPAQ-RVSSPF----SMQALGSPSKLQRLGSASDMPSYATLARVSS------PKQSPSRLAKSYSTSSPINMAAGGGSSSSPLHMAGAGNVS---NSSPLHQLSAAVG--SYATLSPTKRMLHTTDQY-KISHDLYANATLQRPGSLAG-SRGSYSSQHSHLGSELRPLQSPEHHIDPIYEDRVYQKAPLRNFNQAQDP----------------MNQFCDQVLNFLLCPYS-PVIAPSSPGVDSIPLQRTGSQN-----ATGTFPRAGYATGPGASTADYANPYRTLQFCPSTDSPYSKSGPALPPEATLVRSPSVDSIQKDPRYDPEFLVWNQNQAEQRMTKEFGWRDPELPEVIQMLQHQFPSVQSNAAAYLQHLCFGDNKIKSEIRRQGGIQLLVDLLDHRMTDVHRSACGALRNLVYGKANDDNKIALKNCGGIPALVRLLRKTTDVEIRELLTGVLWNLSSCDALKMPIIQDALAVLTNTVIIPHSGWDTSPLQDDRKLHLHSSQVLRNATGCLRNVSSAGEEARRRMRECEGLTDALLYVIQTALGTSEIDSKTIENCVCILRNLSYRLAAETSQGQQMGSEELDGVLCTDASGKDAESSGCWGKKKKKKKSH--DQWDGVGPFPDSSDP-------PKGLQMLWHPSIVKPYLTLLSECSNPDTLEGAAGALQNLAAGSWKVG------------------PTLKPWSVYIRAAVRKEKGLPILVELLRIDNDRVVCAVATALRNMALDVRNKELIGKYAMRDLVHRLPGGNNNNSTG----TGGSSKSMSDDTITAICCALHEVITKNMENTKALRDAGGIEKLIGIARSKGDKHTPKVVKAASQVLNSMWQYRDLRSLYKKDGYSQYHFVGSSSTIERDRQRPYSSSRTPSISPVRTSPNNRSASAPTSPREMMSLKERKTDYESTGSNSTYHGNKGEHTSRKDAMAAQISSGTSTLFRGAYMSPADDIKHNQVSAQGNPPE-------AYPPFQTPPGANFEEPYYEDQAHKRPPPAADGTMHLGLKSTGNYVDFYSASRPYSELNYETSHYPASPDSWV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32TBQ9-1", "uniprot_id": "A0AB32TBQ9_DANRE", "id": "A0AB32TBQ9-1", "name": "", "aln": "--------------MPVPDQT-AEMENATMLSPGLNASNGDGAESETTSAILASVKEQEIQFERLTRELEAERQIVATQLERCKLGSEAGGSMSSISSADEQFRWNTQDGQKDIEDELNTGLELVDSCIRSLQESGILDHQEYVTTDRPSLLSQSSLQLSSNPEGSLQYSASYHSNQTLALSDCLSAPQSQKPQPPPRSSGQPGGAVHSYNQVTSNRAAQLAAGD------------SSQSHGAGLSDSQHSSAASGPGLYYSSSTLPAQ-RISSPLNSMQSTAASGSPTKLQRLGSASDTPGYATTQRLPSSSSSASPKPSPGRLAKSYSSSSPINAVGIGGSPATHASGSPHRLASPPNNASPIYQQLQTTGVASYATLSPTKRLVHSSEQY-KISHELYATATLQRPGSLAG-SRGSYSNQHAHLGPELRPLQSPEHHIEPIYEDRVYQKVPMRSLSQSQGETLPPAHTGTYRNNTDLVNHFCEQVLNFLFCPYSPPAIAPSSPGVDSVPLQRTASQN-----ATGTFPRGGYASGQ---SANYTDTYRTLPYCSSVESPYSKSGPALPPEGNLARSPSIDSIQKDPR-------------------EFGWRDPELPEVIQMLQHQFPSVQSNAAAYLQHLCFGDNKIKAEIRRQGGIQLLVDLLDHRMAEVHRSACGALRNLVYGKANDDNKIALKNCGGIPALVRLLRKTSDVEVRELVTGVLWNLSSCDALKMPIIQDALAVLTNTVIIPHSTWDVSPHQEDRKLQMHTSQVLRNATGCLRNVSSAGEEARRRMRECEGLTDTLLFVIQTSLGSSEIDSKTIENCVCILRNLSYRLAAETSQGQQMGTDELDGLLCSDASGKDGETSGCWGKKKKKKKSQ--DQWDGVGPLPDTAEP-------PKGIQMLWHPSIVKPYLTLLSECSNPDTLEGAAGALQNLAAGSWK-------------------------WSVYIRAAVRKEKGLPILVELLRIDNDRVVCAVATALRNMALDVRNKELIGKYAMRDLVHRLPGGNNASASSGGTANSTAGKTMCDDTVTAICCALHEVITKNMENAKALRDAGGIEKLIGIARSKGDKHSPKVVKAASQVLSSMWQYRDLRSLYKKDGYSQYHFVGSASTIERDRQRPYSSSRTPSVSPVRTSPNNRSASAPASPREMISLKDRKSEFDSTGTNATYHANKGEHTARKDTMAVQTSCGTSTLFRNSYETSNDEIKHNQVPVPPIPQEPPLKDYEPYPIYQNST-RNFEEPFFEDQVHRP-PPATDLNMHLGLKSTGNYVDFYSAARPYSELNYETSHYPASPDSWV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7PLI0-1", "uniprot_id": "Q7PLI0_DROME", "id": "Q7PLI0-1", "name": "", "aln": "--------------------------------------------------------------------------MEARSLKHSLIG------------------LNMNSTHINMDLSLTHEPANMQSQFGSFQNYDQFSAAGYSS---------TPLYITKPTGVGAITKVAPHCSQ---------------------------------NKIETN------------------------STDNSIPDIENHP--------------------------------LATTVRYVQAGQYEDTSEYGVAGLTCG-------------IDSEYTAEAVVPYCYTSDANYTGIQN----------TTSSIKPFS-------------------------------------GRP------FNDNINGAEAVADSQCRTFKSS--------------------------------------------------------AEFKLPQFAMSS--INTVPQRLE--------------EKDDYIEGS---ENDICSTMR-------------------------------------------------------------WRDPNLSEVISFLSNPSSAIKANAAAYLQHLCYMDDPNKQRTRSLGGIPPLVRLLSYDSPEIHKNACGALRNLSYGRQNDENKRGIKNAGGIAALVHLLCRSQETEVKELVTGVLWNMSSCEDLKRSIIDEALVAVVCSVIKPHSGWDAVCCGET-----CFSTVFRNASGVLRNVSSAGEHARGCLRNCEHLVECLLYVVRTSIEKNNIGNKTVENCVCILRNLSYRCQEVDDPNYDKHPFITPERVIPSSS--KGENLGCFGTNKKKKEANNSDALNEYNISADYSKSSVTYNKLNKGYEQLWQPEVVQYYLSLLQSCSNPETLEAAAGAIQNLSACYWQP-------------------------SIDIRATVRKEKGLPILVELLRMEVDRVVCAVATALRNLAIDQRNKELIGKYAMRDLVQKLPSGNVQHDQN-----------TSDDTITAVLATINEVIKKNPEFSRSLLDSGGIDRLMNITKRK-EKYTSCVLKFASQVLYTMWQHNELRDVYKKNGWKEQDFVS----------KHFTAHNTP-----PSSPNNVNN---TLNRPMASQ--GRTRYEDR-------------TIQR---------GTSTLY--SANDSSGAVMSN------------------------------ESAMLSEMVRKQL----------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .::::**********: *: * . * *** ** **.: .::*:.******** **: **:** .:**.***.***:** :: : *::**:******:***: ** .**::**..:. :** *** *: : * *:***:* *********.** :*:*: *.: **:*::::: ..:*..**:************* . . . . : .:. . *. **:*.:****::: * : . ", "identical_positions": 117, "similar_positions": 78, "identity": "8.75%" }, { "cls_id": "homologset.agr.MGI:1195969", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P59901-1", "uniprot_id": "LIRA4_HUMAN", "id": "P59901-1", "name": "Leukocyte immunoglobulin-like receptor subfamily A member 4", "aln": "MTLILTSLLFFGLSLGPRTRVQAENLLKPIL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WAEPGPVITWHNPVTIWCQGTLEAQGYRLDKEGNSM-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SRHILKTLESENKVKLSIPSMMWEHAGRYHCYYQSPAG-WSEPSDPLELVVT-AYSR--PTLSALPSPVVTSGVNVTLRCASRLGLGRFTLIEEGDHRLSWTLNSHQHNHGKFQALFPMGPLTFSNRGTFRCYGYENNTPYVWSEPSDPLQLLVSGVSRKPSLLTLQGPVVT--------------------------------------------------------PGENLTLQCGSDVGYIRYTLYKEG-ADGLPQRPGRQPQAGLSQANFTLSPVSRSYGGQYRCYGAHNVSSEWSAP-SDPLDILIAGQISDRPSLSVQPGP--------TVTSGEKVTLLCQSWDPMFTFLLTK---------------------EGAAHPPLRLR----------SMYGAHKYQAEFPMSPVTSAHAGTYR-CYGSRSSNPYLLSHPSEPLELVVSGATETLNPAQKKSDS-------------KTAPHLQDYTVENL----IRMGVAGLVLLFLGILLFEAQHSQRSPPRCSQEANSRKDNAPFRVVEPWEQI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PI73-1", "uniprot_id": "LIRA6_HUMAN", "id": "Q6PI73-1", "name": "Leukocyte immunoglobulin-like receptor subfamily A member 6", "aln": "MTPALTALLCLGLSLGPRTRVQAGPFPKPTL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WAEPGSVISWGSPVTIWCQGSLEAQEYQLDKEGSPE-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PLDRNNPLEPKNKARFSIPSMTQHHAGRYRCHYYSSAG-WSEPSDPLELVMTGFYNK--PTLSALPSPVVASGGNMTLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSGGFQALFPVGPVTPSHRWRFTCYYYYTNTPRVWSHPSDPLEILPSGVSRKPSLLTLQGPVLA--------------------------------------------------------PGQSLTLQCGSDVGYDRFVLYKEG-ERDFLQRPGQQPQAGLSQANFTLGPVSPSHGGQYRCYGAHNLSSEWSAP-SDPLNILMAGQIYDTVSLSAQPGP--------TVASGENVTLLCQSRGYFDTFLLTK---------------------EGAAHPPLRLR----------SMYGAHKYQAEFPMSPVTSAHAGTYR-CYGSYSSNPHLLSFPSEPLELMVSGHSGGSSLPPTGPPS-------------TPASHAKDYTVENL----IRMGMAGLVLVFLGILLFEAQHSQRNP----QDAAGR---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O75019-1", "uniprot_id": "LIRA1_HUMAN", "id": "O75019-1", "name": "Leukocyte immunoglobulin-like receptor subfamily A member 1", "aln": "MTPIVTVLICLRLSLGPRTHVQAGTLPKPTL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WAEPGSVITQGSPVTLWCQGILETQEYRLYREKKTA-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PWITRIPQEIVKKGQFPIPSITWEHTGRYRCFYGSHTAGWSEPSDPLELVVTGAYIK--PTLSALPSPVVTSGGNVTLHCVSQVAFGSFILCKEGEDEHPQCLNSQPRTHGWSRAIFSVGPVSPSRRWSYRCYAYDSNSPHVWSLPSDLLELLVLGVSKKPSLSVQPGPIVA--------------------------------------------------------PGESLTLQCVSDVSYDRFVLYKEG-ERDFLQLPGPQPQAGLSQANFTLGPVSRSYGGQYRCSGAYNLSSEWSAP-SDPLDILIAGQFRGRPFISVHPGP--------TVASGENVTLLCQSWGPFHTFLLTK---------------------AGAADAPLRLR----------SIHEYPKYQAEFPMSPVTSAHSGTYR-CYGSLSSNPYLLSHPSDSLELMVSGAAETLSPPQNKSDSKAGAANTLSPSQNKTASHPQDYTVENL----IRMGIAGLVLVVLGILLFEAQHSQRSL-------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8N149-1", "uniprot_id": "LIRA2_HUMAN", "id": "Q8N149-1", "name": "Leukocyte immunoglobulin-like receptor subfamily A member 2", "aln": "MTPILTVLICLGLSLGPRTHVQAGHLPKPTL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WAEPGSVIIQGSPVTLRCQGSLQAEEYHLYRENKSA-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SWVRRI-QEPGKNGQFPIPSITWEHAGRYHCQYYSHNH-SSEYSDPLELVVTGAYSK--PTLSALPSPVVTSGGNVTLQCVSQVAFDGFILCKEGEDEHPQRLNSHSHARGWSWAIFSVGPVSPSRRWSYRCYAYDSNSPYVWSLPSDLLELLVPGVSKKPSLSVQPGPMVA--------------------------------------------------------PGESLTLQCVSDVGYDRFVLYKEG-ERDFLQRPGWQPQAGLSQANFTLGPVSPSHGGQYRCYSAHNLSSEWSAP-SDPLDILITGQFYDRPSLSVQPVP--------TVAPGKNVTLLCQSRGQFHTFLLTK---------------------EGAGHPPLHLR----------SEHQAQQNQAEFRMGPVTSAHVGTYR-CYSSLSSNPYLLSLPSDPLELVVSEAAETLSPSQNKTDS----------TTTSLGQHPQDYTVENL----IRMGVAGLVLVVLGILLFEAQHSQRSLQ----DAAGR---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4J1F3-1", "uniprot_id": "A0A0B4J1F3_MOUSE", "id": "A0A0B4J1F3-1", "name": "", "aln": "MSCTFTALLCLGLTLRLWIPVLTGSLPKPILRVQPDSVVQVWTKVTFLCEETIGANEYRLYKDGKLYKTVTKNKQKPANKAEFSFSNVHLRNAGQYRCSYNTQDESSGYSDPLVLVVTGHYWTPSLSAQASPVVTSGGYVTLQCESSQSYHRFILTVEGQQKVSWTQDSQYNISTGKYHALFSVGPVTPNQRWICRCYSYDRNRPYVWSPPSESVELLVSGNLQKTTIKAEPGSVIASKRAMTIWCQGNLDAEVYFLHNERSQK-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TQSTQTLQEPGNKGKFFIPSVRRQHAGQYRCYCYSSAG-WSQPSDTLELVVTGIYEHYEPRLSALPSPVVTAGGKMTLHCASHGHYDKFILTKEDKKFTSSQDTEHISSSRQYRALFIIGPTTPTHTGAFRCYGYYKNTPLLWSVPSALQQILISGLSKKPSLLTHQGHILD--------------------------------------------------------PGMTLTLQCYSDINYDRFALHKVG-GADIMQHSSQQTDTGFSVANFTLGYVSSYTGGQYRCYGAHNLSSEWSAS-SDPLDILISGQLPLTPSLSVQPNH--------TVHSGETVSLLCWSMDSVDTFILSK---------------------EGSAQQPLRLK----------SKSHDQQSQAEFSMSAVTSHLSGTYR-CYGAQDSSFYLLSSASAPVELTVS------------------------------ATENQDHTTENL----IRMGMAVVVLIVLSILATEAWQSHRQTH----PAAGN---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2KBC9-1", "uniprot_id": "LRB3L_RAT", "id": "A0A0G2KBC9-1", "name": "Leukocyte immunoglobulin-like receptor subfamily B member 3-like", "aln": "MTFTFTALLCLGLTLRLWIPVLTGSLPKPILR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VQPDSVVSMGTKVTFVCEETIGVKESHLYRNGNLQRTVLKNHQKPTNKTEFSFSNVDQQ-MQQYQCSYRTQTKSSDYSEPLELVVTGAYSKPSLSAQTNPVVTSGGYVTLKCEPSQDNHTLILTVEGSQKHSWRKDPECNRYTEKCHALFYVGPLTSNQRWIFRCYSYEKHTPQVWSAPSEPVELLVSGKLQKTTIKAEPGSVIRSGRAMTIWCQGDLDAEIYFLHKEGSHNTQSTQTLQQPGNKAKFLIPSVTQRHAGQYRCYCYSSAG-WSEPSDTLELVVTGIY-YYGVKLSGLPSPVVPEGGNVTLHCTSHSNYDKFILTKEDQKFTSSLDAEYIPSTGQHQALFVMGPMTPNYSGTFRCYGYYKHTPQLWSVPSELLKIFISGPSRKPSLLSHQGHILEPGMSLTLQCYSDTKYDKFALYKEGGTDIIESFSQWTKAGLSMTNFTLSVMPNSTVHSGENVTLMCWSTYSVDTFILSKEGSGQPPLRLKSKIQDQQY-QSEFSMSGVTSKLSGTYRCYGSHDSSLY------------------------------------LKALIGVSVAFLLFLFILIFILLRRRHQEKFRKDDEDAQKGKELQLSTGAAEPVTRDRGHQKRSNPAAATQEESLYASVEDMETKDGVELDTWKPPEGDPQGETYAQVEPSR-LRRAGAISP-VVSREQLNTKYEQAEEGQEVDSQATESEEPQDVTYAQLCSRTLRQGTAAPPLSQAGEAPEEPSVYAALATARPGAVPKNKKQ------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "C0HJX3-1", "uniprot_id": "LRB3B_RAT", "id": "C0HJX3-1", "name": "Leukocyte immunoglobulin-like receptor subfamily B member 3B", "aln": "MTFTFTALLCLGLTLGLWIPVLTGSLPKPILR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VQPDSVVSMGTTVTFICEETIGAKQSYLYRNGNLQRRVPKNNQKPTNKTEFLFLNVGHQNAGQYHCSYKSQGKSSDYSEPLELVVTGAYSKPSLSAQTNPVVTSGGYVTLKCEPSHYGHTLILTVEGPQKLSWRQDPQCNYYTENCHVLFYVGPLTSNQRWIFRCYSYETNTPQVWSAPSEPVEILVSGKLQKPTIKAEPGSVIHSGKAMIIWCQGDLDAEIYFLHKEGSHNTQSTQTLQQPGNKAKLFIRPVTQGHAGDYRCYYYSSAG-WSEPSDTLELVVTGIYNYHPLMLSGPPSPVVPEGGNVTLHCTSHRYYDKFILIKEDQKFSSSLDTKYISSTGQHQALFVMGPMTPNYSGTFRCYGYYKHTPQLWSEPSNLLKILITG---------QLHHVLF----------------------------------------------LSVMPNSTVHSGENVTLMCWSTYSVDTFILSKEGSGQPPLRLKSKIQDQQY-QSEFSMSGVTSKLSGTYRCYGSHDSSLYLLSFASAPVELIVSGPIRTSDLPPTMSIPPDGLQRYLKALIGVSVAFLLFLFILIFILLRRRHQEKFRKDDEDAQKGKELQLSTGAAEPVTRDRGHQKRSNPAAATQEESLYASVEDMETKDGVELDTWKPPEGDPQGETYAQVEPSR-LRRAGAISP-VVSREQLNTKYEQAEEGQEVDSQATESEEPQDVTYAQLCSRTLRQGTAAPPLSQAGEAPEEPSVYAALATARPGAVPKNKKQ------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3ZQX2-1", "uniprot_id": "NILR1_RAT", "id": "D3ZQX2-1", "name": "Neutrophil immunoglobulin-like receptor 1", "aln": "MTFTCKALLCLGMTLGLWITVLTEFLPRPILR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VQPDTVVSTQSKVIFFCERSQGAELYCLYKKGNPR----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NPRCKEIRPKPGKKVEFFISKIEPYHAGHYHCYYQIHGQ-WSEDSDALELVVTGVYDYNELRLSVLPSPVVTVGRNMTLHCISHSHYDKFILTKEDHKFTSSLDTQCIPPSGQCQALFVMGPMTSNHTGTFRCYGYYKHTPQLWSIPSEPLEIHISGLSKKPSLLTHQGHILD--------------------------------------------------------PGVNLTLQCCSDINYDRFALYKVG-GVDIMQHTSQQTDTGFSMTNFTLGYVHHSTGGQYRCYGAHNLSSEWSAS-SDPLDILITGPIQMSTLPPITSMPPDQLESYVNALIGVSVAFLVFLFILIFIILQRRHQRKFRKDGEEAQKEKELQYPTGAVEPISRDRDQQKRSNAAAATQEESVYASVEDMETEDGVELDTWKPPEGDPQGETYAQVKPSR-LRRVEAIIPSAMSREQLNTKYEQAEEGQEVDGQATESEEPQDVTYAQLCSRTLRQGTAAPPLSQAGEAPEEPSVYAALATACPGAVPKDKEQ------------", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: . *: : ::* * : : :* * .:*..*: : : *: .: * .: . . : :: .: * : *:* *:* *: **.****:* * ** *****. * ::**:* *: * * :*... . . *:* :** : . : ** * .::* :** ** :: * :: .* .:** * * . : * * * : . : ::*::. * .* *** .::: * .. * .*::* . :: : *: . : : : : * . . .*:: . ... : .* :. : . . :* * :* :* * * * . *. ", "identical_positions": 82, "similar_positions": 112, "identity": "8.1%" }, { "cls_id": "homologset.agr.MGI:1195970", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P59901-1", "uniprot_id": "LIRA4_HUMAN", "id": "P59901-1", "name": "Leukocyte immunoglobulin-like receptor subfamily A member 4", "aln": "MTLILTSLLFFGLSLG------------PRTRVQ-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AENLLKPILWAEPGPVITWHNPVTIWCQGTLEAQGYRLDKEGNSM-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SRHILKTLESENKVKLSIPSMMWEHAGRYHCYYQSPAG-WSEPSDPLELVVT---AYSRPTLSALPSPVVTSGVNVTLRCASRLGLGRFTLIEEGDHRLSWTLNSHQHNHG-KFQALFPMGPLTFSNRGTFRCYGYENNTPYVWSEPSDPLQLLVSGVSRKPSLLTLQGPVVT--------------------------------------------------------PGENLTLQCGSDVGYIRYTLYKEG-ADGLPQRPGRQPQAGLSQANFTLSPVSRSYGGQYRCYGAHNVSSEWSAP-SDPLDILIAGQISDRPSLSVQPGP--------TVTSGEKVTLLCQSWDPMFTFLLTKEGAAHPPLRLRSMYGAHKYQAEFPMSPVTSAHAGTYRCYGSRSSNPYLLSHPSEPLELVVSGATETLNPAQKKSDS--------------------------------------------KTAPHLQDYTVENL----IRMGVAGLVLLFLGILLFEAQHSQRSPPRCSQEANSRKDNAPFRVVEPWEQI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PI73-1", "uniprot_id": "LIRA6_HUMAN", "id": "Q6PI73-1", "name": "Leukocyte immunoglobulin-like receptor subfamily A member 6", "aln": "MTPALTALLCLGLSLG------------PRTRVQ-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AGPFPKPTLWAEPGSVISWGSPVTIWCQGSLEAQEYQLDKEGSPE-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PLDRNNPLEPKNKARFSIPSMTQHHAGRYRCHYYSSAG-WSEPSDPLELVMTG--FYNKPTLSALPSPVVASGGNMTLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSG-GFQALFPVGPVTPSHRWRFTCYYYYTNTPRVWSHPSDPLEILPSGVSRKPSLLTLQGPVLA--------------------------------------------------------PGQSLTLQCGSDVGYDRFVLYKEG-ERDFLQRPGQQPQAGLSQANFTLGPVSPSHGGQYRCYGAHNLSSEWSAP-SDPLNILMAGQIYDTVSLSAQPGP--------TVASGENVTLLCQSRGYFDTFLLTKEGAAHPPLRLRSMYGAHKYQAEFPMSPVTSAHAGTYRCYGSYSSNPHLLSFPSEPLELMVSGHSGGSSLPPTGPPS--------------------------------------------TPASHAKDYTVENL----IRMGMAGLVLVFLGILLFEAQHSQRNP----QDAAGR---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O75019-1", "uniprot_id": "LIRA1_HUMAN", "id": "O75019-1", "name": "Leukocyte immunoglobulin-like receptor subfamily A member 1", "aln": "MTPIVTVLICLRLSLG------------PRTHVQ-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AGTLPKPTLWAEPGSVITQGSPVTLWCQGILETQEYRLYREKKTA-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PWITRIPQEIVKKGQFPIPSITWEHTGRYRCFYGSHTAGWSEPSDPLELVVTG--AYIKPTLSALPSPVVTSGGNVTLHCVSQVAFGSFILCKEGEDEHPQCLNSQPRTHG-WSRAIFSVGPVSPSRRWSYRCYAYDSNSPHVWSLPSDLLELLVLGVSKKPSLSVQPGPIVA--------------------------------------------------------PGESLTLQCVSDVSYDRFVLYKEG-ERDFLQLPGPQPQAGLSQANFTLGPVSRSYGGQYRCSGAYNLSSEWSAP-SDPLDILIAGQFRGRPFISVHPGP--------TVASGENVTLLCQSWGPFHTFLLTKAGAADAPLRLRSIHEYPKYQAEFPMSPVTSAHSGTYRCYGSLSSNPYLLSHPSDSLELMVSGAAETLSPPQNKSDSKAGAANTLS-------------------------------PSQNKTASHPQDYTVENL----IRMGIAGLVLVVLGILLFEAQHSQRSL-------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8N149-1", "uniprot_id": "LIRA2_HUMAN", "id": "Q8N149-1", "name": "Leukocyte immunoglobulin-like receptor subfamily A member 2", "aln": "MTPILTVLICLGLSLG------------PRTHVQ-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AGHLPKPTLWAEPGSVIIQGSPVTLRCQGSLQAEEYHLYRENKSA-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SWVRRI-QEPGKNGQFPIPSITWEHAGRYHCQYYSHNH-SSEYSDPLELVVTG--AYSKPTLSALPSPVVTSGGNVTLQCVSQVAFDGFILCKEGEDEHPQRLNSHSHARG-WSWAIFSVGPVSPSRRWSYRCYAYDSNSPYVWSLPSDLLELLVPGVSKKPSLSVQPGPMVA--------------------------------------------------------PGESLTLQCVSDVGYDRFVLYKEG-ERDFLQRPGWQPQAGLSQANFTLGPVSPSHGGQYRCYSAHNLSSEWSAP-SDPLDILITGQFYDRPSLSVQPVP--------TVAPGKNVTLLCQSRGQFHTFLLTKEGAGHPPLHLRSEHQAQQNQAEFRMGPVTSAHVGTYRCYSSLSSNPYLLSLPSDPLELVVSEAAETLSPSQNKTDS-----------------------------------------TTTSLGQHPQDYTVENL----IRMGVAGLVLVVLGILLFEAQHSQRSLQ----DAAGR---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F8VQ94-1", "uniprot_id": "F8VQ94_MOUSE", "id": "F8VQ94-1", "name": "", "aln": "MSCTFTALLCLGLTLSLWIPVLTGSLPKPILRVQPDSVVSRRTKVTFLCEETIGANEYRLYKDGKLYKTVTKNKQKPANKAEFSFSNVDLSNAGQYECSYSTQYKSSGYSDPLKLVVTEDYWTPSLSAQASPVVTSGGYVTLQCESWPSYDRFILTVAGPQKFSWTQDSQYNYSTRKNHALFSVGPVTPNQRWIFRCYSYDRNRPYVFSAPSESVELLVSGNLQKPTIKAEPGSVITSKRAMTIWCQGNLDAEVYFLHNEKSQK-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TQSTQTLQEPGNKGRFFIPSVTQQHAGQYRCYCYSSAG-WSQPSDTLELVVTGIYEYYEPRLSVLPSPVVTAGGNMTLHCASDFHYDKFILTKE-DKKFTSSLDTEHISSSRQYRALFIIGPTTPTHTGTFRCYGYYKNAPQLWSVPSALQQILISGLSKKPSLLTHQGHTLD--------------------------------------------------------PGMTLTLQCFSDINYDRYALHKVG-RADIMQHSSQQTDTGFSVANFTLGYVSSSTGGQYRCYGAHNLSSEWSAS-SEPLDILITGQLPLTPSLSVQPNH--------TVHSGETVSLLCWSMDSVDTFILSKEGSAQQPLRLKSKSHDQQSQAEFSMSAVTSHLSGTYRCYGAQDSSFYLLSSASAPVELTVSETIESSTWSPKRPIP--------------------------------------------PIPTENKDHTMENL----IRMGMAVLVLIVLSILATEAWRSHRQTH----PAAGN---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2KBC9-1", "uniprot_id": "LRB3L_RAT", "id": "A0A0G2KBC9-1", "name": "Leukocyte immunoglobulin-like receptor subfamily B member 3-like", "aln": "MTFTFTALLCLGLTLR---------LWIPVL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TGSLPKPILRVQPDSVVSMGTKVTFVCEETIGVKESHLYRNGNLQRTVLKNHQKPTNKTEFSFSNVDQQ-MQQYQCSYRTQTKSSDYSEPLELVVTGAYSKPSLSAQTNPVVTSGGYVTLKCEPSQDNHTLILTVEGSQKHSWRKDPECNRYTEKCHALFYVGPLTSNQRWIFRCYSYEKHTPQVWSAPSEPVELLVSGKLQKTTIKAEPGSVIRSGRAMTIWCQGDLDAEIYFLHKEGSHNTQSTQTLQQPGNKAKFLIPSVTQRHAGQYRCYCYSSAG-WSEPSDTLELVVTGIY-YYGVKLSGLPSPVVPEGGNVTLHCTSHSNYDKFILTKE-DQKFTSSLDAEYIPSTGQHQALFVMGPMTPNYSGTFRCYGYYKHTPQLWSVPSELLKIFISGPSRKPSLLSHQGHILEPGMSLTLQCYSDTKYDKFALYKEGGTDIIESFSQWTKAGLSMTNFTLSVMPNSTVHSGENVTLMCWSTYSVDTFILSKEGSGQPPLRLKSKIQDQQY-QSEFSMSGVTSKLSGTYRCYGSHDSSLY------------------------------------LKALIGVSVAFLLFLFILIFILLRRRHQEKFRKDDEDAQKGKELQLSTGAAEPVTRDRGHQKRSNPAAATQEESLYASVEDMETKDGVELDTWKPPEGDPQGETYAQVEPSRLRRAGAISP-VVSREQLNTKYEQAEEGQEVDSQATESEEPQDVTYAQLCSRTLRQGTAAPPLSQAGEAPEEPSVYAALATARPGAVPKNKKQ------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "C0HJX3-1", "uniprot_id": "LRB3B_RAT", "id": "C0HJX3-1", "name": "Leukocyte immunoglobulin-like receptor subfamily B member 3B", "aln": "MTFTFTALLCLGLTLG---------LWIPVL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TGSLPKPILRVQPDSVVSMGTTVTFICEETIGAKQSYLYRNGNLQRRVPKNNQKPTNKTEFLFLNVGHQNAGQYHCSYKSQGKSSDYSEPLELVVTGAYSKPSLSAQTNPVVTSGGYVTLKCEPSHYGHTLILTVEGPQKLSWRQDPQCNYYTENCHVLFYVGPLTSNQRWIFRCYSYETNTPQVWSAPSEPVEILVSGKLQKPTIKAEPGSVIHSGKAMIIWCQGDLDAEIYFLHKEGSHNTQSTQTLQQPGNKAKLFIRPVTQGHAGDYRCYYYSSAG-WSEPSDTLELVVTGIYNYHPLMLSGPPSPVVPEGGNVTLHCTSHRYYDKFILIKE-DQKFSSSLDTKYISSTGQHQALFVMGPMTPNYSGTFRCYGYYKHTPQLWSEPSNLLKILITG---------QLHHVLF----------------------------------------------LSVMPNSTVHSGENVTLMCWSTYSVDTFILSKEGSGQPPLRLKSKIQDQQY-QSEFSMSGVTSKLSGTYRCYGSHDSSLYLLSFASAPVELIVSGPIRTSDLPPTMSIPPDGLQRYLKALIGVSVAFLLFLFILIFILLRRRHQEKFRKDDEDAQKGKELQLSTGAAEPVTRDRGHQKRSNPAAATQEESLYASVEDMETKDGVELDTWKPPEGDPQGETYAQVEPSRLRRAGAISP-VVSREQLNTKYEQAEEGQEVDSQATESEEPQDVTYAQLCSRTLRQGTAAPPLSQAGEAPEEPSVYAALATARPGAVPKNKKQ------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3ZQX2-1", "uniprot_id": "NILR1_RAT", "id": "D3ZQX2-1", "name": "Neutrophil immunoglobulin-like receptor 1", "aln": "MTFTCKALLCLGMTLG---------LWITVL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TEFLPRPILRVQPDTVVSTQSKVIFFCERSQGAELYCLYKKGNPR----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NPRCKEIRPKPGKKVEFFISKIEPYHAGHYHCYYQIHGQ-WSEDSDALELVVTGVYDYNELRLSVLPSPVVTVGRNMTLHCISHSHYDKFILTKE-DHKFTSSLDTQCIPPSGQCQALFVMGPMTSNHTGTFRCYGYYKHTPQLWSIPSEPLEIHISGLSKKPSLLTHQGHILD--------------------------------------------------------PGVNLTLQCCSDINYDRFALYKVG-GVDIMQHTSQQTDTGFSMTNFTLGYVHHSTGGQYRCYGAHNLSSEWSAS-SDPLDILITGPIQMSTLPPITSMPPDQLESYVNALIGVSVAFLVFLFILIFIILQRRHQRKFRKDGEEAQKEKELQYPTGAVEPISRDRDQQKRSNAAAATQEESVYASVEDMETEDGVELDTWKPPEGDPQGETYAQVKPSRLRRVEAIIPSAMSREQLNTKYEQAEEGQEVDGQATESEEPQDVTYAQLCSRTLRQGTAAPPLSQAGEAPEEPSVYAALATACPGAVPKDKEQ------------", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: . *: : ::* . : : :* : .:*..*: : : *: .: * .: . . : :: .: * : *:* *:* *: **.****:* * ** *****. * *:**:* * * * :* :.. . *::. *:* :** : . : ** * .::* :** ** :: * : .* .:** * * . : * * * : . : ::*::. * . .* *** .::: * .. * .*::* . :: : : . .:: *. : :. : . :* . . . . . :* * :* :* * * * . *. ", "identical_positions": 80, "similar_positions": 109, "identity": "7.91%" }, { "cls_id": "homologset.agr.MGI:1195972", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZJF7-1", "uniprot_id": "D3ZJF7_RAT", "id": "D3ZJF7-1", "name": "Telomeric repeat-binding factor", "aln": "MAAGAGTAGPASGPGVVRDPMASQPRKRP------GGEGARRSNTMAGGGGSSDNGGRAANRRASRSGGRARRGRHEPGLGGAAERGAGEARLEEAVNRWVLKFYFHEALRAFRSSRYRDFRQIRDIMQALLVRPLGKEHTVSRLLRVMQCLSRIEEGENLDCSFDMEAELTPLESAINVLEMIKTEFTLTDSMVESSRRLVKEAAVIICIKNKEFEKASKILKKYMSKDPTTQKVRTDLLNIIREKNLAHPVIQNFSYEIFQQKMLRFLESHLDDTEPYLLTMAKK----ALRSESAASSTMKEEKHTEP--VEKPLREPP-RQPRNPPTTIGLRTVKAAFKALSTAQDSEAAFAKLDQKDLVLPNLASPSSPTHKNKRPRKDENESSAPAEGEGGSERQPRNNR-MTISRLVLEEDSQSSEPSPDLNSSRQ-------------------------------------------------------------------------------------ALSASPSKPRALNQPHTGEKNPKASKDKWNSPNGLEE-----------------------------------------------------------------KEVWSEEDQLFEVR-APGEDKSSNLARKQKWTIEESEWVKDGVQKYGEGNWVAISKSYPFVNRTAVMIKDRWRTMKKLGLN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35144-1", "uniprot_id": "TERF2_MOUSE", "id": "O35144-1", "name": "Telomeric repeat-binding factor 2", "aln": "MAAGAGTAGPASGPGVVRDPMASQPRKRPSREGGEGGEGERRSNTMAGGGGSSDSSGRAASRRASRSGGRARRGRHEPGLGGAAERGAGEARLEEAVNRWVLKFYFHEALRAFRSSRYRDFRQIRDIMQALLVRPLGKEHTVSRLLRVMQCLSRIEEGENLDCSFDMEAELTPLESAINVLEMIKTEFTLTDSMVESSRKLVKEAAVIICIKNKEFEKASKILKKYMSKDPTTQKLRTDLLNIIREKNLAHPVIQNFSYEVFQQKMLRFLESHLDDTEPYLLTMAKK----ALKSESAASSTMREEKHPEP--VEKPLREPPSRQPQNPPATIGIRTLKAAFKALSTAQDSEAAFAKLDQKDLVLANLASPSSPAHKHKRPRKDEHESAAPAEGEGGSDRQPRNSP-MTISRLLLEEDSQSTEPSPGLNSSHK-------------------------------------------------------------------------------------AMSAS--KPRALNQPHPGEKKPKASKDKWNSPNGLEE-----------------------------------------------------------------KEVWLEEDQLFEVQ-APGEDRSSSLTRKQKWTIEESEWVKDGVRKYGEGNWAAISKSYPFVNRTAVMIKDRWRTMKKLGMN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15554-3", "uniprot_id": "TERF2_HUMAN", "id": "Q15554-3", "name": "Telomeric repeat-binding factor 2", "aln": "MAAGAGTAGPASGPGVVRDPAASQPRKRPGRE---GGEGARRSDTMAGGGGSSDGSGRAAGRRASRSSGRARRGRHEPGLGGPAERGAGEARLEEAVNRWVLKFYFHEALRAFRGSRYGDFRQIRDIMQALLVRPLGKEHTVSRLLRVMQCLSRIEEGENLDCSFDMEAELTPLESAINVLEMIKTEFTLTEAVVESSRKLVKEAAVIICIKNKEFEKASKILKKHMSKDPTTQKLRNDLLNIIREKNLAHPVIQNFSYETFQQKMLRFLESHLDDAEPYLLTMAKK----ALKSESAASSTGKEDKQPAPGPVEKPPREPA-RQLRNPPTTIGMMTLKAAFKTLSGAQDSEAAFAKLDQKDLVLPTQALPASPALKNKRPRKDENESSAPADGEGGSELQPKNKR-MTISRLVLEEDSQSTEPSAGLNSSQE-------------------------------------------------------------------------------------AASAPPSKPTVLNQPLPGEKNPKVPKGKWNSSNGVEE-----------------------------------------------------------------KETWVEEDELFQVQAAPDEDSTTNITKKQKWTVEESEWVKAGVQKYGEGNWAAISKNYPFVNRTAVMIKDRWRTMKRLGMN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3ART8-1", "uniprot_id": "A0A8M3ART8_DANRE", "id": "A0A8M3ART8-1", "name": "", "aln": "-----------------------------------------------------------------------------------MSDKPCEPSWEQIVNRWSFDFYAFQAFSAFRNGDYTAFTHFINIIESVVVRPVDGHPDMIPQLRLMQFLSRINNGDKLDLTFEEP--KTPLESALDVLESICRDMSVPHPEQQLIRHAISEMLVMVCIRSGEFEKAEEMLKHFSSSSDSAGKKK-LLLNLIRCRRSSHSVLQLSSYSHFKQDMLQFVERLFSVPEPFLLQMLRRSGWPSQRPEVRRSTQNNRRFTGKPSKRTPPHSSAAEDHGAECVSAVSRQGLQQVFDLLSEQYGVGISFFQLQDSVEVEAQQQQEGGVAGPELCLTLSETPMQTVILSDTEEQDEPRRYAGMTISRLVQEEDSQISAEHTHIEDDEEEEQTHTHRGGDWVVVLSDLESDDLDVQAGPVSSPSLRHTPKNRQNQHSSLSEPQCSSTQRSTPARLCKRSNTRVQQSESESQSSPAHCSTPARPSHPSNPRSSTRKKTPSRRRIIESSDSENEQTTPAAATHTPRGQRQQHRSIRVSSGSEPEVDSTSPAAHTRRSTPTSTHTRTTKRSKWLDASGIQDNWSDEDSLFHTSTAPAKKYT-----RKMWSVQESEWLKQGVVRYGVGHWERIRSSFPFAGRTAVNLKDRWRTMVKLKMV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . *. *: **** :.** .:*: ***.. * * :: :*:::::***:. . : **:** ****::*::** :*: ******::*** * ::::... : *: :.* *::**:. *****.::**:. *.. :: * : ***:** :. :*.*:* **. *:*.**:*:* :. .**:** * :: : :.* *: .. * * ... : : :::. :: .*. ** . :* :*::. * . .. : . .* : .: .: :*:. ******: ***** : . ::...: * .:. :* .:* .. :: . .: : .... *: :: * :**.**.. ** :. : :: *:::****:* ** :** *:* * ..:**..**** :******* :* : ", "identical_positions": 136, "similar_positions": 166, "identity": "19.4%" }, { "cls_id": "homologset.agr.MGI:1195976", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZPX9-1", "uniprot_id": "D3ZPX9_RAT", "id": "D3ZPX9-1", "name": "Elongation of very long chain fatty acids protein 3", "aln": "----------------------------------------MDTSMNFSRGLKTELIQPYDFEMSQD-LRPFLEEYWVSSFFIVLVYLLLIIFGQNYMKT--RKGFSLQRPLILWSFCLAIFSILGTLRMWKFMGTVLFTMGLKQTVCFTDYTN-DAIVKFWSWVFLLSKVVELGDTAFIILRKRPLIFVHWYHHSTVLLFTSFGYKNKVPSGGWFMTMNLGVHSVMYTYYTMKAAKVKHPNILPMVITSLQILQMVLGTIFGILNYIWRQERG------------CYTTSEHFFWSFVLYGTYFILFAQFFHRAYLRPK----------------RKAESKSQ-------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35949-1", "uniprot_id": "ELOV3_MOUSE", "id": "O35949-1", "name": "Very long chain fatty acid elongase 3", "aln": "----------------------------------------MDTSMNFSRGLKMDLMQPYDFETFQD-LRPFLEEYWVSSFLIVVVYLLLIVVGQTYMRT--RKSFSLQRPLILWSFFLAIFSILGTLRMWKFMATVMFTVGLKQTVCFAIYTD-DAVVRFWSFLFLLSKVVELGDTAFIILRKRPLIFVHWYHHSTVLLFTSFGYKNKVPSGGWFMTMNFGVHSVMYTYYTMKAAKLKHPNLLPMVITSLQILQMVLGTIFGILNYIWRQEKG------------CHTTTEHFFWSFMLYGTYFILFAHFFHRAYLRPK----------------GKVASKSQ-------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HB03-1", "uniprot_id": "ELOV3_HUMAN", "id": "Q9HB03-1", "name": "Very long chain fatty acid elongase 3", "aln": "----------------------------------------MVTAMNVSHEVN-QLFQPYNFELSKD-MRPFFEEYWATSFPIALIYLVLIAVGQNYMKE--RKGFNLQGPLILWSFCLAIFSILGAVRMWGIMGTVLLTGGLKQTVCFINFID-NSTVKFWSWVFLLSKVIELGDTAFIILRKRPLIFIHWYHHSTVLVYTSFGYKNKVPAGGWFVTMNFGVHAIMYTYYTLKAANVKPPKMLPMLITSLQILQMFVGAIVSILTYIWRQDQG------------CHTTMEHLFWSFILYMTYFILFAHFFCQTYIRPK----------------VKAKTKSQ-------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VV87-1", "uniprot_id": "ELOV6_DROME", "id": "Q9VV87-1", "name": "Very long chain fatty acid elongase 6", "aln": "-----------------------------------------MINMDISVTPNYSYIFDFENDFIHQRTRKWMLENWTWVFYYCGIYMLVIFGGQHFMQN--RPRFQLRGPLIIWNTLLAMFSIMGAARTAPELIHVLRHYGLFHSVCVPSYIEQDRVCGFWTWLFVLSKLPELGDTIFIVLRKQPLIFLHWYHHITVLIYSWFSYTEYTSSARWFIVMNYCVHSVMYSYYALKAARFNPPRFISMIITSLQLAQMIIGCAINVWANGFLKTHGTSS---------CHISQRNINLSIAMYSSYFVLFARFFYKAYLAPGGHKSRRMAASLAAQNVVKQSSSPQQASESSKFIGAGEDQAAYLRKAKAQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39540-1", "uniprot_id": "ELO1_YEAST", "id": "P39540-1", "name": "Fatty acid elongase 1", "aln": "MVSDWKNFCLEKASRFR--------------PTIDRPFFNIYLWDYFNRAVGWATAGRFQPKDFEFTVGKQPLSEPRPVLLFIAMYYVVIFGGRSLVKS--CKPLKLRFISQVHNLMLTSVSFLWLILMVEQMLPIVYRHGLYFAVCNVESWT--QPMETLYYLNYMTKFVEFADTVLMVLKHRKLTFLHTYHHGATALLCYNQLVGYTAVTWVPVTLNLAVHVLMYWYYFLSASGIR--VWWKAWVTRLQIVQFMLDLIVVYYVLYQKIVAAYFKNACTPQCEDCLGSMTAIAAGAAILTSYLFLFISFYIEVYKRG------------------SASGKKKINKNN--------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P40319-1", "uniprot_id": "ELO3_YEAST", "id": "P40319-1", "name": "Fatty acid elongase 3", "aln": "MNTTTSTVIAAVADQFQSLNSSSSCFLKVHVPSIENPFG-IELWPIFSKVFEYFSG--YPAEQFEFIHNKTFLANGYHAVSIIIVYYIIIFGGQAILRALNASPLKFKLLFEIHNLFLTSISLVLWLLMLEQLVPMVYHNGLFWSICSKEAFA--PKLVTLYYLNYLTKFVELIDTVFLVLRRKKLLFLHTYHHGATALLCYTQLIGRTSVEWVVILLNLGVHVIMYWYYFLSSCGIR--VWWKQWVTRFQIIQFLIDLVFVYFATYTFYAHKYLD-GILPNKGTCYGTQAAAAYGYLILTSYLLLFISFYIQSYKKGGKKTVKKESEVSGSVASGSSTGVKTSNTKVSSRKA---------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. : . . . :* ::* *: :: :.:: : . *: .*:: : :: ** ::* :: ::*. *: ** :::*::: * *:* *** :. : .. : :* ** :** ** :.:. .. :* :*: *:.:. . * : . : :*:.** *: . * . ", "identical_positions": 35, "similar_positions": 71, "identity": "9.51%" }, { "cls_id": "homologset.agr.MGI:1195985", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6ACN6-1", "uniprot_id": "A0A8I6ACN6_RAT", "id": "A0A8I6ACN6-1", "name": "", "aln": "MELPAVG---------------EHVFAVESIEKKRIRKGRVEYLVKWRGWSPKYNTWEPEENILDPRLLIAFQNRERQEQLMGYRKRGPKPKPLVVQVPTFARRSNVLTGLQDSSADNRAKLELGTQGKGQGHQYELNSKKHHQYQPHGKERSGKPPPPGKSGKYYYQLNSKKHHPYQPDPKMYDLQYQGSHKEAPSPTCPDLGAKSHPPDKWAHGAAAKGYLGAVKPLGGGAGAPGKGSEKGPPNGLTPAPKEAVAGNGIGGKMKIVKNKNKNGRIVIVMSKYMENGMQAVKIKSGEAAESEARSPSHKKRAAEERHPQADRTFKKAAGASEEKKAEVPCKRREEEALVSGDPQPQDLGSRKLSPTKEAFGEQPLQLTTKPDLLAWDPARSSHPPAHH------HHHHHHHHHHHTVGLNLSHARKRCLSETHGEREPCKKRLTARSISTPTCLGGSPVSEHPANVSPTAASLPQPEVILLDSDLDEPIDLRCVKMRSDAGEPPSTLQVKPEAP-----AVAAVVAPATAAEKPPAEAQEEPAEPLSEFKPFFGNIIITDVTANCLTVTFKEYVTV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O55187-1", "uniprot_id": "CBX4_MOUSE", "id": "O55187-1", "name": "E3 SUMO-protein ligase CBX4", "aln": "MELPAVG---------------EHVFAVESIEKKRIRKGRVEYLVKWRGWSPKYNTWEPEENILDPRLLIAFQNRERQEQLMGYRKRGPKPKPLVVQVPTFARRSNVLTGLQDSSADNRAKLELGTQGKGQGHQYELNSKKHHQYQPHSKERSGKPPPPGKSGKYYYQLNSKKHHPYQPDPKMYDLQYQGGHKEAPSPTCPDLGTKSHPPDKWAHGAAAKGYLGAVKPLGGGAGAPGKGSEKGPPNGMTPAPKEAVTGNGIGGKMKIVKNKNKNGRIVIVMSKYMENGMQAVKIKSGEAAEGEARSPSHKKRAAEERHPQGDRTFKKAAGASEEKKAEVPCKRREEEALVSGDAQPQDLGSRKLSPTKEAFGEQPLQLTTKPDLLAWDPARSSHPPAHH------HHHHHHHHHHHTVGLNLSHARKRCLSETHGEREPCKKRLTARSISTPTCLGGSPVSEHPANVSPTAASLPQPEVILLDSDLDEPIDLRCVKMRSDAGEPPSTLQVKPEAP-----AVAAVVAPAPASEKPPAEAQEEPVEPLSEFKPFFGNIIITDVTANCLTVTFKEYVTV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00257-1", "uniprot_id": "CBX4_HUMAN", "id": "O00257-1", "name": "E3 SUMO-protein ligase CBX4", "aln": "MELPAVG---------------EHVFAVESIEKKRIRKGRVEYLVKWRGWSPKYNTWEPEENILDPRLLIAFQNRERQEQLMGYRKRGPKPKPLVVQVPTFARRSNVLTGLQDSSTDNRAKLDLGAQGKGQGHQYELNSKKHHQYQPHSKERAGKPPPPGKSGKYYYQLNSKKHHPYQPDPKMYDLQYQGGHKEAPSPTCPDLGAKSHPPDKWAQGAGAKGYLGAVKPLAGAAGAPGKGSEKGPPNGMMPAPKEAVTGNGIGGKMKIVKNKNKNGRIVIVMSKYMENGMQAVKIKSGEVAEGEARSPSHKKRAADERHPPADRTFKKAAGA-EEKKVEAPPKRREEEVSGVSDPQPQDAGSRKLSPTKEAFGEQPLQLTTKPDLLAWDPARNTHPPSHHPHPHPHHHHHHHHHHHHAVGLNLSHVRKRCLSETHGEREPCKKRLTARSISTPTCLGGSPAAERPADLPP-AAALPQPEVILLDSDLDEPIDLRCVKTRSEAGEPPSSLQVKPETPASAAVAVAAAAAPTTTAEKPPAEAQDEPAESLSEFKPFFGNIIITDVTANCLTVTFKEYVTV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P26017-1", "uniprot_id": "PC_DROME", "id": "P26017-1", "name": "Polycomb group protein Pc", "aln": "MTGRGKGSKGKLGRDNATDDPVDLVYAAEKIIQKRVKKGVVEYRVKWKGWNQRYNTWEPEVNILDRRLIDIYEQTNKSSGTPSKRGIKKKEK---EPDPEPESEEDEYTFTENDVDTHQATTSSATHDKESKKEKKHHHHHHHHHHIKSERNSGRRSESPLT-------HHHHHHHHESKRQRIDHSSSSNSSFTHNSFVPEPDSNSSSSEDQPLIGTKR--KAEVLKESGKIGVTIKTSPDGP--TIKPQPTQQVTPS---------------------QQQPFQDQQQAEKIAS------EAATQLKSEQQATPLATEAINTTPAESGAEEEEVANEEGNQQAPQVPSENNNIPKPCNNLAINQKQPLTPLSPRALPPR----FWLPAKCNIS---------------NRVVITDVTVNLETVTIRECKTERG----FFRERDMKGDSSPVA---------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . * : *:*.*.* :**::** *** ***:**. :******* **** **: ::: ::.. . * * * * ..: * ::. ::*. . .::.* . :: : : ::**::: :.:..:*: . . : : ::** ::.. : * . ... . : .. *: .::* ..:. . . : . * .* *.. * * .** : * *.: *: . .: ::: ** ** * ** : :.:: * . . .* :** **: .: ::: :. .: *: .. :. .: .* *..: * **: . . :: * :**. . * . :* :. :. *:*.. ", "identical_positions": 82, "similar_positions": 143, "identity": "14.21%" }, { "cls_id": "homologset.agr.MGI:1196217", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P0DKR2-1", "uniprot_id": "TCAIM_RAT", "id": "P0DKR2-1", "name": "T-cell activation inhibitor, mitochondrial", "aln": "MLGSWRAFSEMFCHLRPWRRFCLRKVLPPWLHYSRALSGAEAINALRPFYFAVHPDFFGQHPREREVNENSLKRLSVYLENLQKPGFKSLK-PTQLTFYIREKTAQNSSEGQEPVSTTGFRAVRFTLHSSDLLSTVLYILNSCSLPVEHVQSLNTNVHSQPLKEATGMP-DRPIKWHRS--YYSFTGFKDPDEDLEHVSRVETTLTSWLGSNGKGAVKKLKNSLPLRKELDRLKNELSELLQLSDIRWQRGWGVAHRCSQLHSLSRLAQ--QNLEPLQNAKGCTIVFTDRSGMSALGHVMLGTMDVHHHWTRLFESLPNYFDLQRRMSALEDQISHLLGGIQVVYIEELQPALTLDEYYSLLDTFYNQLQRSR---APPR--PQSLSGLQMILS--RYAPSLHELGHFNIPALSDPASLQSFMRTKAQQARENMRRREKLKVIENELIQASTRKFSLEKLYKEPSISSRQMVDCCKRLLEQSLPYLHGMHLCVSHFYSVMQDGDLCIPWNWKKGEAMK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q66JZ4-1", "uniprot_id": "TCAIM_MOUSE", "id": "Q66JZ4-1", "name": "T-cell activation inhibitor, mitochondrial", "aln": "----------MFCHLRPLRRFGLRKVLPHWLHYSRALSGAEAINALRPFYFAVHPDFFGQHPREREVNENSLKRLSVYLENLQKPGFKSLK-PTQLTFYIREKTAQNSSEGQEPISTTGFRAVRFTLHSSDLLSTVLYILNSCSLPVEHVQSLNTNVHSQPLKEATGMP-DRPIKWHRS--YYSFTGFKDPDEDLTHVSRVETTLTSWLGSNGKGAVKKLRNSLPLRKELDRLKNELSELLQLSDIRWQRGWGVAHRCSQLHSLSRLAQ--QNPGPLQNVKGCTVVFTDRSGMSALGHVMLGTMDVHHHWTRLFESLPSYFDLQRRMSALEAQISNLLGGIQVVYIEELQPALTLDQYYSLLHTFYNQLLRSR---VPPHPHPQSLSGLQMILSSDRYAPSLHELGHFDIPALSDPASLQSFMRTKAQQARENMTRREKLKVMENELIQASTKQFSLEKLYKEPSISSRQMVDCCKRLLEQSLPYLHGMHLCVSHFYSVMQDGDLCIPWNWKKGEAMK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N3R3-1", "uniprot_id": "TCAIM_HUMAN", "id": "Q8N3R3-1", "name": "T-cell activation inhibitor, mitochondrial", "aln": "----------MFCHLRPMRRLCLEKIFPHWFPFSRALSGAEAVNALRPFYFAVHPDFFGQHPVEREINENSLKRLSVYLENLQKPGFKSLK-PTQLTFYVRE-TDQSSSDGQEPFSTSGFRAVKFTLHTRDLLSTVLYILNSCSLSVEHIQSLNTNMHTQPLKEAKRMP-DRPIKWDKS--YYSFTGFKDPDEDLEQVSRVETTLTSWLDNNGKSAVKKLKNSLPLRKELDRLKDELSHQLQLSDIRWQRSWGIAHRCSQLHSLSRLAQ--QNLETLKKAKGCTIIFTDRSGMSAVGHVMLGTMDVHHHWTKLFERLPSYFDLQRRLMILEDQISYLLGGIQVVYIEELQPVLTLEEYYSLLDVFYNRLLKSR---ILFH--PRSLRGLQMILNSDRYAPSLHELGHFNIPTLCDPANLQWFILTKAQQARENMKRKEELKVIENELIQASTKKFSLEKLYKEPSISSIQMVDCCKRLLEQSLPYLHGMHLCISHFYSVMQDGDLCIPWNWKNGEAIK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QHT7-1", "uniprot_id": "F1QHT7_DANRE", "id": "F1QHT7-1", "name": "", "aln": "---------MYVTTFLRYIRLGGRCVSARVLQR-RNLSGADAINALRPFYFAVHPDFFGQHPREREVNENSLKRLNGYLENIQKPGERFPK-PTNFTFYVRDTKEKSDPNG--SLLVSGFRSVSFTLQSKDVLSTVLDVLRSCSLSVEHMQDVLKHETTKSSTQQPGTAFYRPIKWDKT--YYTFTGFRDPEQELEQARRVEPTLSLWLRKNEPEATKKQNASLPHREELKRLKRELIQKLGLLNIRWQRKWGVAHKCSQLQSLSRLST--QSPEALLNLRGHIIIFTDQSGMNASGHVMLGTTDVHHQWTKLFERLPSYRSLFEQSAALKERISHLLGGIHVVHMERLGPGLTLEEHYNTLSSFLRRVSPQR---LSLH--PRSLQGLLMTLENDRSTPCLHEMGHFIIPTMCDTLQLQNFLQSQAHEARRRMLSKDKLEAEEEDIISSCLEDLCLRSLSKEPSVSSNQMIPCCRRLMEERSPQMQGLHLCVSHFYSVMQDGDLCIPWNWKG-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VRT6-1", "uniprot_id": "Q9VRT6_DROME", "id": "Q9VRT6-1", "name": "T-cell activation inhibitor, mitochondrial", "aln": "------------MSMSLGSKIRKLVTSRRHFLLLRRSLNQDLTTALRPFYFAVHPDFFAQHPEQRNTNENSLKLLSEHLEALYERRQRSGD-TQVLKFYVRTSSDAD-KRDSFKLIQIRTDWQ----STRDPKTFIQGLLESCNLSTEYVKN--IKAQPEPPKTSG--LDFKPSHDYHY--DMEFAEFETQLKN--ERASKRPVLTTWLEENAGTAKQRSKETADLQAEIDKLKKMLVEKLELQDARYECGWNIEHYRGCLKTLERLSN--THLLEMASLKGRIVVFAPFTGISLEGHVMLFTGDVLSTWIDFIKNIPHHDAYLKVVPVYERTLSQVLLNIQIGRRKF-MPKQQASGYASYLMKVTTSLSDYLGKQKYPPEWPKTLKEFTIVVESEAGPLMVSPTGQFITPATCPGSILVDFISVNLELARERMKKYAQDKHIEQELMDSCIKQLQLQSLTKDDAITPDKMITSLRDLYQLQLKELQGCKLHITHYYSVLTDGVVCIPWDFLQR----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W4Z5-1", "uniprot_id": "Q9W4Z5_DROME", "id": "Q9W4Z5-1", "name": "", "aln": "------------------MVTLRFLTPRRIVDYCRRLLSTDLVTALRPFYQAIRTDGLAHNPAEKRVNEESLRLLCSHLESLTGPSASCLPPDGHLEFYIPSGSDESGSRVVSRLVRVQVDR-----SLLDPRAVICQILRSCKLLPKEKEQEQMKRGQEMEKELGKVLRKEPVRERVRPPQAPVQKNLSALRELFKDAKREHSLEIWMRQ--ALARSQASEVATLRGKIEGIEAALVQLLGIRGTRYDCGCNMERYHNCLSILKGLSEDPKVAGQLGALRNRFVVFAPYTGISLEGDVMLFSGDSPSGWLAFLSEMRLHEEQLRLVPLYEKALSAVLLGIRIERRRVPEPGCEARAYAGSLRRVIRAVSEHLRLEDSVQELPASLQDHHLAIVPDSDIPKVSQTGLFLAPASCSGPDLVEFICRNLDVASGRFSRYRRDIQVERQLWRQCQEELGLQRLSKDDSVTPDKMVMAIRHLLQSGVKSCRGLSLHITNYWSVPTDGIVCIPWDFMSREK--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * . : .****** *::.* :.::* ::. **:**: * :** : : **: . . . * : : :*.**.* : :. : : . .* : . .: . . * *: . * .: : ::. :: * . * : . *:: .: : . * *. *: : :. ::*: :*:. *.*** : * * ::. : : . : :* :* .*:: . * : . * . : * :* : : : * * *: . * *: : . * .: . *.:: . ..: *. * *: :::. :*: . : * : :* * :::::** ** :****:: ", "identical_positions": 71, "similar_positions": 129, "identity": "13.71%" }, { "cls_id": "homologset.agr.MGI:1196221", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0AC58G0B8-1", "uniprot_id": "A0AC58G0B8_DANRE", "id": "A0AC58G0B8-1", "name": "", "aln": "-----------MGNSKHKDHFEGRLIMRYYFIVLLSSTIFCSTGFDVVQEDTVKIVEAGGDVNFTCIFPGHVPSTKAWFKQTTVGKYLQIVSLDLKK-QLKWNSSFEKTNRFNVTKVDDYFNLTILKTKPSDSATYYCVVSAYETIGMGSATRLLVKDAAADRNT--------TLHQSLIETVDPGDSVNLQCSIFTESCAG-DHSVYWFKQSSGHPE-GVLYTKGERNGRCKNNT--ESQTQSCVYSLHKNNISRSDSGIYYCAVDQCGEILFGRGTQLNIRE---YFDFNPGLLAL-GISNIMFLALVVVLGIKLCRS--QIKTSAS----QTTQDEDGLN--YASITFRQKPLNTRRARAKFTQDQS--LYAQVRSHQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1QG83-1", "uniprot_id": "F1QG83_DANRE", "id": "F1QG83-1", "name": "", "aln": "--------------------------MRYYFI-LLSSTIFCSFGVEVVQENNVKIAAAGEDVNLPCTFSRLLQATKAWFKQTADGKSLQIVSLYLDQ-IPNWNNNSE--NGFNIMKEDGYFNLTILKTKPSDSATYYCVISTAYNIGMGSGTRLFVRDSAKDRNT--------TLHQSLIDTVDPGDSVNLQCSIFTESCAG-DHSVYWFKQSSGDSE-GVLYTKGERNGRCKDST--ESQTQSCVYSLHKNNISRSDSGIYYCAVASCGEILLGRGTQLNIRE---SGHLYPGLLALFGVLNIIFLALAVFLGFKLFRG--QRKT-------QESLNQDSLN--YAAITFRQKPLNTKRARAQITQEQS--LYAQVRSLQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q5VTQ5-1", "uniprot_id": "Q5VTQ5_DANRE", "id": "Q5VTQ5-1", "name": "", "aln": "--------------------------MRYYFIVLLSSTIFCSIGFDVVQEDNVKIVEAGEDVNFTCKFPELVQSINAWFKQTTDGKSLQIVSSYLNQ-QPSWNHNFEKTNRFIVANENGYFNLTIFKTKPLDSATYYCVISAYQTIGMGSGTRLLVGDSATDRNS--------TLHQSLIDTVDPGDSVNLQCSIFTESCAG-DHSVYWFKQSSGDSE-GVLYTKGERNGRCKNST--ESQTQSCVYSLHKNNISRSDSGIYYCALAACGQILLGRGTQLNIRE---SDAVNPTLIAL-GILNVIFLVYAVFVTIELRNK--VRLDICG----EDILILADQNDLIAGLNVKFSEEHSFVKYSMIMQKNAYKTLQAIRSST", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AC58G3K4-1", "uniprot_id": "A0AC58G3K4_DANRE", "id": "A0AC58G3K4-1", "name": "", "aln": "-----------MSKSESADFYQSFKMIHCFFILLLYLLTCTSDNANKQGQNHVKIIQAGDAVNLTCIFPKESRTSVVWVKQRVGEKPLLIASAYQGL-AGKYENDFDKQNRFFIEKDEGSFNLSIANTEISDTATYYCVAYVYEFI-FGNSTDLIVNAGELNIKS--------EHQR--------SESEDLQCSVISQSCAE-EHKVYWFRQRSGESPPGVIYTQNNRSAQCEKSSDRNSAAHKCIYSLPKTDE---DPAIYYCAVVACGQILFG--DVVTIPG---FWTLWKTVALALAISNSLLMIVIIFLGMRFYKF--QKNDRTQNIQLGQLMDEDRGVLNYAALSFQQKSSTSRRPKEKHLR--------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AC58G3I5-1", "uniprot_id": "A0AC58G3I5_DANRE", "id": "A0AC58G3I5-1", "name": "", "aln": "MIRQLIQLMFYTADALPAATQCCKMSLQSSFTFFFLIFAYGTCEEDFIHQQPLVVAELGSRVTLPCFHSDDYVTTVSWTKHSAGKKPLLIAYSDFNSGRVTYQNAFNNTNRFFITVASGSYNLTIIHLEKEDFATYYCVKDFLNRLMFGEGTILLRKETDRISSTS-------VIQQPVSDRLHPGDSVTLQCSVSSHICAG-HYRVYWFKRSSGYSQPGFIYTHDNRSDQCLESSEKSSFVQSCVYSLSQTELTTSDAGVYYCAVDTCGKIHFGNGTKLTIEA---SSFWNPVVVILFTISVTSIVANIVLVLQNRRKE--TTEQLRG-----QINQIETDDLNYAALHFSKTKPSTSRRSSIKTIQETIYSETTVH---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1PDP1-1", "uniprot_id": "A0A8M1PDP1_DANRE", "id": "A0A8M1PDP1-1", "name": "", "aln": "-----------------------MNHIIYVIIFLFHPQVSGKNNCTVDQVDEVLTTQEGHIVLLPCLLLEDHFHRVIWYKQVLGEKPVVIVSSYHHSQPNEFSSDFKETQRFHAVRKADSFNLTIRRTLKSDSGTYFCGSAFANVVSFGTGTILLVKG--ADLKPA-------VIQHPVHAFIKPESNVTLRCSVEGKTCDKGVQSVYWFRQSLNTTHQGIVYTHGKSKNECADSS----DTQSCLQNLAKMSVDVSEAGLYYCSVVTCDEVLFGNGTTLVIKDGFISESIQKCILIGLTVLSAVSLTINILLSLPLRRNGGKPQQMQTNDDITRVQFQNADDVNYAALNLSSKRGQRKMTLEKTPTQTNAAR--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4J241-1", "uniprot_id": "TVAM1_HUMAN", "id": "A0A0B4J241-1", "name": "T cell receptor alpha variable 13-1", "aln": "----------------------MTSIR-AVFIFLWLQLDLVN-GENVEQHPSTLSVQEGDSAVIKCTYSDSASNYFPWYKQELGKGPQLIIDIRSNVGEKKDQ-----RIAVTLNKTAKHFSLHITETQPEDSAVYFCAAS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4J235-1", "uniprot_id": "TVAM2_HUMAN", "id": "A0A0B4J235-1", "name": "T cell receptor alpha variable 13-2", "aln": "----------------------MAGIR-ALFMYLWLQLDWVSRGESVGLHLPTLSVQEGDNSIINCAYSNSASDYFIWYKQESGKGPQFIIDIRSNMDKRQGQ-----RVTVLLNKTVKHLSLQIAATQPGDSAVYFCAEN------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A075B652-1", "uniprot_id": "A0A075B652_MOUSE", "id": "A0A075B652-1", "name": "", "aln": "----------------------MKTYAPTLFMFLWLQLDGMSQGEQVEQLPSILRVQEGSSASINCSYEDSASNYFPWYKQEPGENPKLIIDIRSNMERKQIQ-----ELIVLLDKKAKRFSLHITDTQPGDSAMYFCAAS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AC58FZ12-1", "uniprot_id": "A0AC58FZ12_DANRE", "id": "A0AC58FZ12-1", "name": "", "aln": "---------------MWPNAQRTLTMIAFLLIFFLPFRTGLITSDAVFQKKVLESFTAGQTVTLDCLISVNLENYFSWFKQTLGEAPTCIVSLYAESSTPVFYGEFKNNHRMSVQKEKNTFVLIIKEAKPSDAGIYYCGARDYDLITFSNGLFLNYKVASTKQHHIKQFLSGPNLGTEHEPEFNPGDSVNLHCSVLTERCEE-NHRIYWFRHESGDAHPGLIYKDGNTTDQCEKRS--EKDVQSCIYNLPKKNLNLTDAGVYYCAVATCGEILFGNGSRINIREASSKFSWTDVKVPVLASTNILCLVIIVILLCKRAQKQKQKFSESQPLQTTLSSTPANEDISYAAVHLSGSSRHETEKGSCTHVVYSTARGYSIKE--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : * : * * *: * . * * * . *:* ", "identical_positions": 10, "similar_positions": 7, "identity": "2.62%" }, { "cls_id": "homologset.agr.MGI:1196223", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q571I4-1", "uniprot_id": "PRAG1_MOUSE", "id": "Q571I4-1", "name": "Inactive tyrosine-protein kinase PRAG1", "aln": "-------------MSACSDFVEHIWKPGSCKNCFCLRSDHQPTAGHPKARANSLPAGTRLPARPENCRLDDEGVNGLAYSKPTIAVKPTMMTSETSDLWTEASLSAEVPKVNWRRTPGKLLLPKQEDEPIVYLGSFRGLQKPASPLACTDGNSRCPPAYTMVGLHNLEARVDRNTAFQPVSFQEEKAGREE--------LPSAHESFRQKLAAFAGMTSSCPKGPRPCTSPQPLRESLPSEDDSDQRCSPSGDSEGGEYCSILDCCPES--KDAVHSTEGS-GRRGG-DCSPTCREQGPRTRPTEEEKQGLSFPRECCGQGSTANPPRLGPKKPSLNSEAASSSDGLSCGS---SRSGASSPFAPHLENDYCSLVKEPASGKQQDLSGHFLTSGKCVGQAAELQPASLLRDPVQPEPIYAESAKRKKAAPGPPRPEPKKEQVPAGHSQGQVWTGDTWIQKTPPSWSQDREGANPAPQVATTITVIAAHPEEDHRTIYLSSPDSAVGVQWPRGPSNQDLQAGEEEPLVAQGLTSRESHPHNVTENTAKEKPAIPPKLSKSSPGGSPVSP------APPLTDHSDGNTGGSSVGPQLLSRVPANLTSSCHTNGVATAGDSAKCPPPATSSSVLDQRRPRYQTGAWSRQCRIEEEEEVGQELS-QSWGRELENGTADHSNSSTWHRLHPIDGTSGQNSKTNSGMSKSASFAFEFPKDRGRLEAFSPPPPPPKSRHLLKMNKSSSDLEKVSQSSAESLSPSFRGAHVSFTTGSTDSLASDSRPCSDGGPSYEPTHSPTISGKKLFAPVPFPSGSTEDVSPGGGPAQPPPLPQKKIVSRAASSPDGFFWTQGSPKPRTASPKLNLSHSETNVCAHDEPPFNCSLNSGNRSHHVFSSSEPLGKAFKGNAPWAPALGLANSKGGCGSPSLQCRAATSTSSSQLSVSSQASSSSTQLQLHSLLSSISSKEGTYAKLGGLYTQSLARLVTKCEDLFMGGQKKELRFNENYWSLFKLTCNKPCCDSGDAIYYCATCSEDPGSIYAVKICKTPEPKSASYCSPSVPVHFNIQQDCGHFVASVPSSMLASPDTSSKDTAPAVSPQPPAQEQDCVVVITREVPHQTASDFVRDSMASHRAEPEVYERRVCFLLLQLCNGLEHLKEHGIIHRDLCLENLLLAHCNPQSSPG----PSATPTVPTTTSRCPSAAP--------AATTACQGGPGEKQLPRLIISNFLKAKQKPGGTTNLQQKKSQARLAPEIVSASQYRKFDEFQTGILIYELLHQPNPFEVRAQLRERDYRREDLPPLPTLSLYSPGLQQLAHLLLEADPIKRIRIGEAKRVLQCLLWGPRRELVEQPCTSEEVLCNTLHNWIDMKRALMMMKFAEKAVDRRRGVELEDWLCCQYLASAEPGALLQSLKLLQLL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZMK9-1", "uniprot_id": "PRAG1_RAT", "id": "D3ZMK9-1", "name": "Inactive tyrosine-protein kinase PRAG1", "aln": "-------------MSACSDFVEHIWKPGSCKNCFCLRSDHQLTAGHPKARASSLPAGARLPARPEICRLEDEGVNGLAYSKPTIAVKPTMMTSETADLWTEASLSAEVPKVNWRRTPGKLLLQKQEDGPIVYLGSFRGMQKAAGPLACTDSNSRCPPAYTMVGLHNLEARVDRNTALQPVNFQEEKAGREE--------LPSAQESFRQKLAAFTGMTSSCLKGPRPCTSPQPLRESLPSEDDSDQRCSPSGDSEGGEYCSILDCRPES--RDAVHNTEGS-GRRRG-DCSPICWEQGTCTRPTEEEKQALNFPRECCGQGSTANPPHLGPKKPSLNSEAASSSDGLSCGS---SRSGANSPFAPHLENDYCSLVKEPTSVKQQDSGCHLVNSGKYVGQAVDLQPPALPREAVQPEPIYAESAKRKKAAPVPQRPEPKKEQVSS----GQVWTGDTWSQKTPSGWSQEREGPNAAPQVATTITVIAAHPEEDHRTIYLSSPDSAVGVQWPRGSLNQDLHGSGEEPLVVQGLSSRESHPHNMTENSSKEKPAIPPKLSKSSPGGSPVSPA-----APPLTDHSDGNTSGSSVGSQPSSRVPTNLTSSCQTNGVA-AGDPAKCPPQAN-SSVLDQRRPRYQTGAWSRQCRIEEEEEVGQELLSQSWGRELENGIADHSNSSTWHRLHPIDGASGQNGKTNSGMSKSASFAFEFPKDRGRLESFSPPPPPPKSRHLLKMNKSSSDLEKVSQSSAESLSPSFRGAHVSFTTGSTDSLASDSRTCSDGGPSCEATHSPTISGKKLFAPVPFPSGSTEDVSPSG-PAQPPPLPQKKIVSRAASSPDGFFWTQGSPKPRTASPKLNLSHSETNVCAHDEPPLSYSLNSGNHPHHVFSSSEPLEKAFKGSVPWAPALGPANSKGGCGSPNLQGRAATSTSSSQLSVSSQASTGSSQLQLHSLLSSISSKEGTYAKLGGLYTQSLARLVTKCEDLFMGGLKTELRFDENSWSLFKLICNKPCCDSGDAIYYGATCSKDPDSIYAVKICKTPEPKSASYCSPSVPVHFNIQQDCGHFVASVPSSMLAFPDTSSKDPAPAAPSHTPAQEQDCVVVITREVPHQTASDFVRDSVASHRAEPEVYERRVCFLLLQLCNGLEHLKEHGIIHRDLCLENLLLVHCNPQSSPG----PSANPSVPTTTSRCPSAAP--------AATTACQGGPGEKHLPRLIISNFLKAKQKPGGTTNLQQKKSQARLAPEIVSASQYRKFDEFQTGILIYELLHQPNPFEVRAQLRERDYRREDLPPLPTLSLYSPGLQQLAHLLLEADPIKRIRIGEAKRVLQCLLWGPRRELVEQPCPSEEVLCNTLHNWIDMKRALMMMKFAEKAVERRRGVELEDWLCCQYLASAEPGALLQSLKLLQLL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q86YV5-1", "uniprot_id": "PRAG1_HUMAN", "id": "Q86YV5-1", "name": "Inactive tyrosine-protein kinase PRAG1", "aln": "MHQTLCLNPESLKMSACSDFVEHIWKPGSCKNCFCLRSDHQLVAGPPQPRAGSLPPPPRLPPRPENCRLEDEGVNSSPYSKPTIAVKPTMMSSEASDVWTEANLSAEVSQVIWRRAPGKLPLPKQEDAPVVYLGSFRGVQKPAGPSTSPDGNSRCPPAYTMVGLHNLEPRGERNIAFHPVSFPEEKAVHKEKPSFPYQDRPSTQESFRQKLAAFAGTTSGCHQGPG------PLRESLPSEDDSDQRCSPSGDSEGGEYCSILDCCPGSPVAKAASQTAGSRGRHGGRDCSPTCWEQGKCSGPAEQEKRGPSFPKECCSQGPTAHPSCLGPKKLSLTSEAAISSDGLSCGSGSGSGSGASSPFVPHLESDYCSLMKEPAPEKQQDPGCPGVTPSRCLGLTGEPQPPAHPREATQPEPIYAESTKRKKAAPVPSKSQAKIEHAAAAQGQGQVCTGNAWAQKAASGWG--RDSPDPTPQVSATITVMAAHPEEDHRTIYLSSPDSAVGVQWPRGPVSQNSEVGEEETSAGQGLSSRESHAHSASESKPKERPAIPPKLSKSSPVGSPVSPSAGGPPVSPLADLSDGSSGGSSIGPQPPSQGPADPAPSCRTNGVA-ISDPSRCPQPAA-SSASEQRRPRFQAGTWSRQCRIEEEEEVEQELLSHSWGRETKNGPTDHSNSTTWHRLHPTDGSSGQNSKVGTGMSKSASFAFEFPKDRSGIETFSPPPPPPKSRHLLKMNKSSSDLEKVSQGSAESLSPSFRGVHVSFTTGSTDSLASDSRTCSDGGPSSELAHSPTNSGKKLFAPVPFPSGSTEDVSPSG-PQQPPPLPQKKIVSRAASSPDGFFWTQGSPKPGTASPKLNLSHSETN--VHDESHFSYSLSPGNRHHPVFSSSDPLEKAFKGSGHWLPAAGLAGNRGGCGSPGLQCKGAPSASSSQLSVSSQASTGSTQLQLHGLLSNISSKEGTYAKLGGLYTQSLARLVAKCEDLFMGGQKKELHFNENNWSLFKLTCNKPCCDSGDAIYYCATCSEDPGSTYAVKICKAPEPKTVSYCSPSVPVHFNIQQDCGHFVASVPSSMLSSPDAP-KDPVPALPTHPPAQEQDCVVVITREVPHQTASDFVRDSAASHQAEPEAYERRVCFLLLQLCNGLEHLKEHGIIHRDLCLENLLLVHCTLQAGPGPAPAPAPAPAPAAAAPPCSSAAPPAGGTLSPAAGPASPEGPREKQLPRLIISNFLKAKQKPGGTPNLQQKKSQARLAPEIVSASQYRKFDEFQTGILIYELLHQPNPFEVRAQLRERDYRQEDLPPLPALSLYSPGLQQLAHLLLEADPIKRIRIGEAKRVLQCLLWGPRRELVQQPGTSEEALCGTLHNWIDMKRALMMMKFAEKAVDRRRGVELEDWLCCQYLASAEPGALLQSLKLLQLL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **************************** .** *:.**.***. .***.*** ***:*****. .*************:**::*:****.*****.:* ***:**** * **** *:********:**.*.* :..*.*****************.* :** *::**.* **** ::* **::**********:* **.* :** ********************************* * * .*. .* ** **: * **** * *** : *:*:**:. .**:***.**.**:*. ***** **.**** ********* * ***.***.****.*****:***:. **** . :...: :* : : **.: *:..*********:******* * :.:.* *:..: *** **::* **:...*. *:..:.:***::****:***************************. .*: . . **. . ***:*****.*. :*...**:************ ****** ..**:* ***.:.***:*.* *: *:: :.**:***** .*.::** * **. :*****:*:*:************* *** :***** :** :*****:******* **:****.*..:****************. :*:****************************.***********.*****************.******* * :**** *********************.* * ****************************** ************** .***. :. **..**: * *****:** *****. * ** * *..:******.** :.*.*:************:.*:*****.***.***********************:********* *.**:*:** ****** ************** ****:**.* *******:****:.*****************************: **:. **..** ..:.*************************** ***:****.************************************.**. *:.** *:. *: .:::. *.**** ** .*. ** **:*******************.*******************************************************:*******:*********************************************:** .***.**.**********************:**********************************", "identical_positions": 1028, "similar_positions": 220, "identity": "72.39%" }, { "cls_id": "homologset.agr.MGI:1196224", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R3L8-1", "uniprot_id": "CDK8_MOUSE", "id": "Q8R3L8-1", "name": "Cyclin-dependent kinase 8", "aln": "-----------MDYDFKVKLSSERERVEDLFEYEGCKVG-------------------------------------------RGTYGHVYKAKRKDGK---------------------------------------------------------------------------------------DDKDYALKQIEGTGISMSACREIALLRELKHPNVISLLKVFLSHADRKVWLLFDYAEHDLWHIIKFHRASKANKKPVQLPRGMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCR--QEDIKTSNPYHHDQLDRIFNVMGFPADKDWEDIKKMPEHSTLMKDFRRNTYTNCSLIKYMEKHKVKPDSKAFHLLQKLLTMDPIKRITSEQAMQDPYFLEDPLPTSD-VFAGCQIPYPKREFLTEEEPDEKGDKKTQQQQQGNNHTNGTGHPGNQDSGHAQGPPLKKVRVVPPTTTSGGLIMTSDYQRSNPHAAYPN--------PGPSTSQPQSS--------------------------------MGYSATS-QQPPQYSHQTHRY--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49336-1", "uniprot_id": "CDK8_HUMAN", "id": "P49336-1", "name": "Cyclin-dependent kinase 8", "aln": "-----------MDYDFKVKLSSERERVEDLFEYEGCKVG-------------------------------------------RGTYGHVYKAKRKDGK---------------------------------------------------------------------------------------DDKDYALKQIEGTGISMSACREIALLRELKHPNVISLQKVFLSHADRKVWLLFDYAEHDLWHIIKFHRASKANKKPVQLPRGMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCR--QEDIKTSNPYHHDQLDRIFNVMGFPADKDWEDIKKMPEHSTLMKDFRRNTYTNCSLIKYMEKHKVKPDSKAFHLLQKLLTMDPIKRITSEQAMQDPYFLEDPLPTSD-VFAGCQIPYPKREFLTEEEPDDKGDKKNQQQQQGNNHTNGTGHPGNQDSSHTQGPPLKKVRVVPPTTTSGGLIMTSDYQRSNPHAAYPN--------PGPSTSQPQSS--------------------------------MGYSATS-QQPPQYSHQTHRY--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8JH47-1", "uniprot_id": "CDK8_DANRE", "id": "Q8JH47-1", "name": "Cyclin-dependent kinase 8", "aln": "-----------MGYDFKVKLTGERERVEDLFEYEGCKVG-------------------------------------------RGTYGHVYKAKRKDGK---------------------------------------------------------------------------------------DDRDYALKQIEGTGISMSACREIALLRELKHPNVISLQKVFLSHADRKVWLLFDYAEHDLWHIIKFHRASKANKKPLQLPRGMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLSNSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCR--QEDIKTSNPYHHDQLDRIFNVMGFPADKDWEDIKKMPEHSTLMKDFRRNTYTNCSLIKYMEKHKVKPDSKAFHLLQKLLTMDPIRRITSEQAMQDPYFLEEPLPTSD-VFAGCQIPYPKREFLTEEEPEDKADKKNQQQQQGNNHTNGAGHTGNPDNSHAQGPPLKKVRVVPPTATSSGLIMTSDYQRSNPHAAYQN--------PGPSTSLPQSS--------------------------------MGYSSTS-QQPPQYSHQTHRY--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8I5ZVW8-1", "uniprot_id": "A0A8I5ZVW8_RAT", "id": "A0A8I5ZVW8-1", "name": "Cyclin-dependent kinase 8", "aln": "-----------MDYDFKVKLSSERERVEDLFEYEGCKVG-------------------------------------------RGTYGHVYKAKRKDGK---------------------------------------------------------------------------------------DDKDYALKQIEGTGISMSACREIALLRELKHPNVISLQKVFLSHADRKVWLLFDYAEHDLWHIIKFHRASKANKKPVQLPRGMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCR--QEDIKTSNPYHHDQLDRIFNVMGFPADKDWEDIKKMPEHSTLMKDFRRNTYTNCSLIKYMEKHKVKPDSKAFHLLQKLLTMDPIKRITSEQAMQDPYFLEDPLPTSD-VFAGCQIPYPKREFLTEEEPDEKGDKKNQQQQQGNNHTNGTGHPGNQDSGHAQGPPLKKVRVVPPTTTSAFQSTCCLSQPWTKHITAPEQHGILSYLPAASTVLTSDTSVLSCAGVCPCTVAHAAGLAAALCGNLVWAMRMYCTTTSSQCPVAEFHSCHRSGR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VT57-1", "uniprot_id": "CDK8_DROME", "id": "Q9VT57-1", "name": "Cyclin-dependent kinase 8", "aln": "-----------MDYDFKMKTQIERTKVEDLFNYEGCKVG-------------------------------------------RGTYGHVYKAKWKETS---------------------------------------------------------------------------------------DGKEYALKQIDGTGLSMSACREIALLRELKHQNVITLIRVFLSHNDRKVFLLIDYAEHDLWHIIKFHRAAKATKKQVVVPRGMVKSLLYQILDGIHYLHSNWVLHRDLKPANILVMGDGNERGRVKIADMGFARLFNAPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCR--QEDIKTSNPYHHDQLDRIFNVMGFPQDKDWEDIKKMPEHHTLTKDFKRSTYSTCSLAKYMERHKIKPDSKAFHLLQKLLLMDPNKRITSEQAMQDQYFQEEPQPTQD-VFAGCPIPYPKREFLTDDDQEDKSDNKRQQQQQQQQQQQQQQQQQQQQQQQQQQQQMN----AEPNAKRVRLSGAGNQQDFHHQQQQQQ--------QQQQQQQQQQQ----------------------------------------QMMFNQQQNFQRFN-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39073-1", "uniprot_id": "SSN3_YEAST", "id": "P39073-1", "name": "Meiotic mRNA stability protein kinase SSN3", "aln": "MYNGKDRAQNSYQPMYQRPMQVQGQQQAQSFVGKKNTIGSVHGKAPMLMANNDVFTIGPYRARKDRMRVSVLEKYEVIGYIAAGTYGKVYKAKRQINSGTNSANGSSLNGTNAKIPQFDSTQPKSSSSMDMQANTNALRRNLLKDEGVTPGRIRTTREDVSPHYNSQKQTLIKKPLTVFYAIKKFKTEKDGVEQLHYTGISQSACREMALCRELHNKHLTTLVEIFLER--KCVHMVYEYAEHDLLQIIHFHSHPEKR----MIPPRMVRSIMWQLLDGVSYLHQNWVLHRDLKPANIMVTIDG----CVKIGDLGLARKFHNMLQTLYTGDKVVVTIWYRAPELLLGARHYTPAVDLWSVGCIFAELIGLQPIFKGEEAKLDSKKTVPFQVNQLQRILEVLGTPDQKIWPYLEKYPEYDQITKFPKYRDN----LATWYHSAGGR-DKHALSLLYHLLNYDPIKRIDAFNALEHKYFTESDIPVSENVFEGLTYKYPARRIHTND------NDIMNLGSRTKNNTQASGITAGAAANALGGLGVNRRILAAAAAAAAAVSGNNASDEPSRKKNRR---------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : : : * : .:* ****:***** : . . .. .::*:. **:* *****:** ***:: :: :* .:**.: : * :: :****** :**:** .: :* **:*:::*:***: *** *************:* :* ***.*:*:** : *:.* * ****:*************** *:*:*::*******: :***: . : * *.: *:: :**:**::*:* * :* * ::* **: : * : * .: . : *.:*: ** :** ** :** : :*::. ** *. *..: ** * ** *.: *:: :. : .: ::: : :: . . : : : ", "identical_positions": 146, "similar_positions": 116, "identity": "22.43%" }, { "cls_id": "homologset.agr.MGI:1196227", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LL66-1", "uniprot_id": "A0ABK0LL66_RAT", "id": "A0ABK0LL66-1", "name": "DNA fragmentation factor subunit alpha", "aln": "MELSRGASAPDPDDVGPLKPCLLRRNHSREQHGVAASSLEELRSKACELLAIDKSLTPVTLVLAEDGTIVDDEDYFLCLPSNTKFVALACNEKWAY------------NDSDGGTAWLSQES-FDTDQTDSGAGVKWKNVARQLKEDLSSIILLSEEELQALIDIPCAELAQELCQSCATVQGLQSTLQQVLDQREEARQSKQLLELYLQALEKEGSILSNQNESKAALGEELDAVDTGVGGEVASEVMLRSQILAALKEKPAPELSLSSQDLESVSKEDPKALAVALSWDIKKAETVQQACTTELALRLQQVQSLHSLRNLSAKRKPLP-GDPQSPKRAKVDFS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O54786-1", "uniprot_id": "DFFA_MOUSE", "id": "O54786-1", "name": "DNA fragmentation factor subunit alpha", "aln": "MELSRGASAPDPDDVRPLKPCLLRRNHSRDQHGVAASSLEELRSKACELLAIDKSLTPITLVLAEDGTIVDDDDYFLCLPSNTKFVALACNEKWIY------------NDSDGGTAWVSQES-FEADEPDSRAGVKWKNVARQLKEDLSSIILLSEEDLQALIDIPCAELAQELCQSCATVQGLQSTLQQVLDQREEARQSKQLLELYLQALEKEGNILSNQKESKAALSEELDAVDTGVGREMASEVLLRSQILTTLKEKPAPELSLSSQDLESVSKEDPKALAVALSWDIRKAETVQQACTTELALRLQQVQSLHSLRNLSARRSPLP-GEPQRPKRAKRDSS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00273-1", "uniprot_id": "DFFA_HUMAN", "id": "O00273-1", "name": "DNA fragmentation factor subunit alpha", "aln": "MEVTGDAGVPESGEIRTLKPCLLRRNYSREQHGVAASCLEDLRSKACDILAIDKSLTPVTLVLAEDGTIVDDDDYFLCLPSNTKFVALASNEKWAY------------NNSDGGTAWISQES-FDVDETDSGAGLKWKNVARQLKEDLSSIILLSEEDLQMLVDAPCSDLAQELRQSCATVQRLQHTLQQVLDQREEVRQSKQLLQLYLQALEKEGSLLSKQEESKAAFGEEVDAVDTGISRETSSDVALASHILTALREKQAPELSLSSQDLELVTKEDPKALAVALNWDIKKTETVQEACERELALRLQQTQSLHSLRSISASKASPP-GDLQNPKRARQDPT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4KFQ3-1", "uniprot_id": "A0A0B4KFQ3_DROME", "id": "A0A0B4KFQ3-1", "name": "", "aln": "METAANSGDSK-------KPFKVKDVTRNIKKAVCASSLEEIRSKVAEKFEKCDHLP--TIHLDSDGTEIDDEEYFRTLDENTELVAVFPGEHWIDPTHYVTITTPHGNEAGTGNGELNGGGEGDTTDANNSESARIRQLVGQLQNNLCNVSVMNDADLDSLSNMDPNSLVDITGK--EFMEQLKDAGRPLCAKRNAEDR------LNLLKLLKAGAIFCSER-----YPEDAEAIDREIGRQLN----------EAESGQMSTTTTSNTRTIEVVQCDNQ-----NTTITITVGEATTTCATASGAMGSSAAEAAANEANANPNRNPNANGDIXLPILGSLR--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** : .:. .. ** :: . ::.*.**.**::***..: : . *. *: * .*** :**::** * .**::**: .*:* *::. *.. :. . :. :.:. . : :::. **:::*..: ::.: :*: * : .*.: : :: *: : : : :*: : * * * * * ::..:. *: :*:* :. : : : :. : .:: :* * :: . * *:. .. . *: . .:: . . .. : . . *: * . ", "identical_positions": 54, "similar_positions": 122, "identity": "15.65%" }, { "cls_id": "homologset.agr.MGI:1196228", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5EB97-1", "uniprot_id": "ZCH10_RAT", "id": "Q5EB97-1", "name": "Zinc finger CCHC domain-containing protein 10", "aln": "--MATPMHRLIARRQA----------------------EANKQHVRCQKCLEFGHWTYECKGKRKYLHRPSRTAELKKALKEKENR-LLQQSMGETNTERKTKKKRRPKSVTS--TSSSDSSASESSSESE-TSASSSSEDSDADGSLSSSSSSSAYSS-SSSSSSSSSSSSSDSDSSSSSSSSSSS-ESSSDDEPPKKRKKK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CX48-1", "uniprot_id": "ZCH10_MOUSE", "id": "Q9CX48-1", "name": "Zinc finger CCHC domain-containing protein 10", "aln": "--MATPMHRLIARRKA----------------------EANKQHVRCQKCLEFGHWTYECKGKRKYLHRPSRTAELKKALKEKENR-LLLQSIGETNIEKKIKKKKRSKSVTSSSTSSSDSSASESSSESE-TSASSSSEDSDSDESLSSSSSSSSSSACSSSSSSSSSSSSSDSDSSSSSSSSSSSSESSSDDEPQKKKKKKK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TBK6-1", "uniprot_id": "ZCH10_HUMAN", "id": "Q8TBK6-1", "name": "Zinc finger CCHC domain-containing protein 10", "aln": "--MATPMHRLIARRQAFDTELQPVKTFWILIQPSIVISEANKQHVRCQKCLEFGHWTYECTGKRKYLHRPSRTAELKKALKEKENRLLLQQSIGETNVERKAKKK-RSKSVTSSSSSSSDSSASDSSSESEETSTSSSSEDSDTDESSSSSSSS-------ASSTTSSSSSDSDSDSSSSSSSSTST-DSSSDDEPPKKKKKK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VF05-1", "uniprot_id": "Q9VF05_DROME", "id": "Q9VF05-1", "name": "Zinc finger CCHC domain-containing protein 10", "aln": "MTLVGLAARKLAQKKR-----------------SAKQAADFPNGIRCQKCLQIGHWSYECKEKRKYVHRSSRTKQLSKRMSQKEADAPKNQVEEHSEVASSEGKKVRRKRKTSKSSSSSSSSSDSSDSSSE----SGSSSESDSSSSSSDSDDE-------EGSSSDSSGSGSDSDSSEDQKQGAPQKKKKRAGSSPESSDDQE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. * :*::: : :******::***:***. ****:**.*** :*.* :.:** * .:: . ** * * ** :***.**:..*.*.** *.**.:**:. * *.*... .*::.**.*.******......:. ... ... :. ..: ", "identical_positions": 61, "similar_positions": 64, "identity": "29.9%" }, { "cls_id": "homologset.agr.MGI:1196234", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZTN8-1", "uniprot_id": "D3ZTN8_RAT", "id": "D3ZTN8-1", "name": "", "aln": "MGCRHSRHS--------------------------------------------------------------------------------RGKRAEKVE-ETQTELLETLDKEGRILEGRHEETGQVQQTSNAQEKDALSDCVLEAKASLQNTCAIHVPPQEARQAKMNKVDGSILSRLYRNHIQDYGSPGPFWEQELESLHHVIEMKNERIHELEKQLFLLEMLVAATRAVLGASSLAPQEGWQPSHCRQRLRKEKEKNLILALKNTTLQQEVEDLQFQARNRLAMSRQLRKDLLQD---LEKESQNGHCCNRRRSH------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3TCJ8-1", "uniprot_id": "CCD69_MOUSE", "id": "Q3TCJ8-1", "name": "Coiled-coil domain-containing protein 69", "aln": "MGCRQSRHS--------------------------------------------------------------------------------RGKRAEKVE-ETQTELLEALDKEGRILEGRHEEAGQVPQTSNAQEKVSLSDCIQEAKASLQNTCASHVSPQEATQAKMNKVDGSILSRLYRNHIQDYGSPGPFWEQELESLHHVIEMKNERIHELEKQLFLLEML-------------------------------KEKNLILALKNTTLRQEVEDLQFQAGNRLTMSRQLRKDLLQD---LEKESQNGHCCSRRRSH------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NI79-1", "uniprot_id": "CCD69_HUMAN", "id": "A6NI79-1", "name": "Coiled-coil domain-containing protein 69", "aln": "MGCRHSRLSSCKPPKKKRQEPEPEQPPRPEPHELGPLNGDTAITVQLCASEEAERHQKDITRILQQHEEE-------------------KKKWAQQVEKERELELRDRLDEQQRVLEGKNEEALQVLRASYEQEKEALTHSFREASSTQQETIDRLTSQLEAFQAKMKRVEESILSRNYKKHIQDYGSPSQFWEQELESLHFVIEMKNERIHELDRRLILMETV-------------------------------KEKNLILEEKITTLQQENEDLHVRSRNQVVLSRQLSEDLLLTREALEKEVQLRRQLQQEKEELLYRVLG-ANASPAFPLAPVTPTEVSFLAT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A7MC22-1", "uniprot_id": "CCD69_DANRE", "id": "A7MC22-1", "name": "Coiled-coil domain-containing protein 69", "aln": "MGCHNSKVCGQVSKKKKKNKAQEGEKRTKDIKLQDGRGTHSSEEERCCLENQLENYEWQLKILHAVLTASGDQEREQLLKDHPGDICTLVHSITEKVKTEISADLNDLHEQQMRSVSEQHQSETEELQRLHSEEKNVLNESHAAAEEALKDQIEDLTSELKLFNELKRRAEASTLKRDLQRNIETHGSPGEFWEQEQESLLFVIEMKRQNLQDQGNKLLQMEAQ-------------------------------VEKNLSLEDQLLQALQQNEDFRVRIENYQSLIQQLSKEQNDMQEVLEKQSLQNQKLIQEKEELLFKLLHRRDSCSTFHLPSVIPTQVSPS--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***::*: . . :::*: * . :* : ::: * :. :::. : : :** *... *. : :: .. : : .:.: * *.* :.:*: :***. ***** *** .*****.:.::: .:*: :* **** * : *: **::.: * : :** :: ***: : :.:.. ", "identical_positions": 48, "similar_positions": 74, "identity": "13.83%" }, { "cls_id": "homologset.agr.MGI:1196246", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LSC4-1", "uniprot_id": "A0ABK0LSC4_RAT", "id": "A0ABK0LSC4-1", "name": "E3 ubiquitin-protein ligase ZNRF1", "aln": "MGAKQSGP-AANG----RTRAYSGSDLP--------------------SGT-SGGGGADGARA--------------------------ARFAAPVPGAQQPSASASTAAAAAAAAAAAAAAAASAPAAPRSRSLGGAVGSAASG-RAAQSAFSIPSSGGGS-GGPYGSQ-----DSVHSSPEDGVGSRDRDRPAGGGPGGP---RLVIG-SLPAHLSPHLFGGFKCPVCSKFVPSDEMDLHLVMCLTKPRITYNGIISHFSCFCFLLLSLRVQEKVNPQVKRLTCDGARPLIGWEDEPFSCWMLSERACEDVLSKDAGECAICLEELQQGDTIARLPCLCIYHKGCIDEWFEVNRSCPEHPSD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q71FD5-1", "uniprot_id": "ZNRF2_MOUSE", "id": "Q71FD5-1", "name": "E3 ubiquitin-protein ligase ZNRF2", "aln": "MGAKQSGP-AANG----RTRAYSGSDLP--------------------SGTGSGGGGADGARA--------------------------ARFAAPVSGAQQPSASAG--------AAAAAAAAASAPAAPRSRSLGGAVGSASGG-RAAQSAFSIPSAGGG--GGPYGSQ-----DSVHSSPEDSVGARDRDRPAGGGPGGP---RLVIG-SLPAHLSPHLFGGFKCPVCSKFVPSDEMDLHLVMCLTKPRITYN-------------------------------------------------------EDVLSKDTGECAICLEELQQGDTIARLPCLCIYHKGCIDEWFEVNRSCPEHPSD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NHG8-1", "uniprot_id": "ZNRF2_HUMAN", "id": "Q8NHG8-1", "name": "E3 ubiquitin-protein ligase ZNRF2", "aln": "MGAKQSGPAAANG----RTRAYSGSDLPSSSSGGA-------------NGTAGGGGGARAAAA--------------------------GRFPAQVPSAHQPSASGG---------AAAAAAAPAAPAAPRSRSLGGAVGSVASGARAAQSPFSIPNSSSG----PYGSQ-----DSVHSSPEDGGGGRD--RPVGGSPGGP---RLVIG-SLPAHLSPHMFGGFKCPVCSKFVSSDEMDLHLVMCLTKPRITYN-------------------------------------------------------EDVLSKDAGECAICLEELQQGDTIARLPCLCIYHKGCIDEWFEVNRSCPEHPSD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q08CN9-1", "uniprot_id": "ZNRF2_DANRE", "id": "Q08CN9-1", "name": "E3 ubiquitin-protein ligase znrf2", "aln": "MGAKQSSP-AANG----RTRAYSGSDLP--------------------SATASVNG--RTAAV--------------------------LRYNNSQ-GASGATSAAS---------ASSSAAVASQFISSRTRSVGPSAR--------PQSGINIPN--SG----AYSSA-----DSGNSTPEEPGGERER------STGAP---RLVIG-SLPAHLSPHLFGGFKCPVCSKFISSDEMDLHLVMCLTKPRVTYN-------------------------------------------------------EDVLSKDAGECAICLEELLQGDTIARLPCLCIYHKGCIDEWFEVNRSCPEHPAD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W3V3-1", "uniprot_id": "Q9W3V3_DROME", "id": "Q9W3V3-1", "name": "E3 ubiquitin-protein ligase ZNRF1", "aln": "MGQKASTP-ATSGQQSPRSRTFSSSSTGAADSALQQQQHQHSNPGQNRGGNGGGGGGNDTTGQGFNLLRTLPGLQVYHNQNSTSIDRQRARSLSSVPDIQQQAQQQQQQGS---ITSSGSSPHSHPHAAHGHPAVGVTVSVSGNANANSNSNFTAAGNNNGSAMQSYMQQRRTLGDSIRDMSMTGGSIAESIALAASATSANGIGRVYTATSLPSHIWS--FNGIKCPVCNKFVLPDDIECHLVMCLTKPRLSYN-------------------------------------------------------EDVLSDAKGECVICLEDLSPGDTIARLPCLCIYHKGCIDRWFEVNRSCPEHPGD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** * * * *:.* *:*::*.*. ... . .* : * . : ::.::. . : ::* :. .:* :. .. .* .* . ** .. . . : .... *: . ***:*: . *.*:*****.**: .*::: **********::** *****. ***.****:* *******************.************.*", "identical_positions": 91, "similar_positions": 65, "identity": "25.0%" }, { "cls_id": "homologset.agr.MGI:1196250", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O70215-1", "uniprot_id": "NKG2D_RAT", "id": "O70215-1", "name": "NKG2-D type II integral membrane protein", "aln": "--------------MSKCHNYDLKPAKWDTSQEHQKQRSALPTSRPGENGIIRRRSSIEELKISPLFVVRVLVAAMTIRFTVITLTWLAVFIT----LLCNKEVSVSSREGYCGPCPNDWICHRNNCYQFFNENKAWNQSQASCLSQNSSLLKIYSKEEQDFLKLVKSYHWMGLVQSPANGSWQWEDGSSLSPNELTLVKTPSGTCAVYGSSFKAYTEDCSNPNTYICMKRAV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O54709-1", "uniprot_id": "NKG2D_MOUSE", "id": "O54709-1", "name": "NKG2-D type II integral membrane protein", "aln": "MALIRDRKSHHS-EMSKCHNYDLKPAKWDTSQEQQKQRLALTTSQPGENGIIRGRYPIEKLKISPMFVVRVLAIALAIRFTLNTLMWLAIFKETFQPVLCNKEVPVSSREGYCGPCPNNWICHRNNCYQFFNEEKTWNQSQASCLSQNSSLLKIYSKEEQDFLKLVKSYHWMGLVQIPANGSWQWEDGSSLSYNQLTLVEIPKGSCAVYGSSFKAYTEDCANLNTYICMKRAV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P26718-1", "uniprot_id": "NKG2D_HUMAN", "id": "P26718-1", "name": "NKG2-D type II integral membrane protein", "aln": "MGWIRGRRSRHSWEMSEFHNYNLDLKKSDFSTRWQKQRCPVVKSKCREN-------------ASPFFFCCFIAVAMGIRFIIMVTIWSAVFLN----SLFNQEVQIPLTESYCGPCPKNWICYKNNCYQFFDESKNWYESQASCMSQNASLLKVYSKEDQDLLKLVKSYHWMGLVHIPTNGSWQWEDGSILSPNLLTIIEMQKGDCALYASSFKGYIENCSTPNTYICMQRTV", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **: ***:*. * * * . **** .: .*: ** **:*. .:. *: *** : . * *:* * *:** :. *.******::***::*******:*.* * :*****:***:****:****:**:*************: *:********** ** * **::: .* **:*.****.* *:*:. ******:*:*", "identical_positions": 116, "similar_positions": 47, "identity": "49.79%" }, { "cls_id": "homologset.agr.MGI:1196251", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZS43-1", "uniprot_id": "A0A8I5ZS43_RAT", "id": "A0A8I5ZS43-1", "name": "", "aln": "-------------MDLGT-------------------AESTRCTDPPAGKPPMAAKRKGGLKLNAICAKLSRQVVVEKGAEAG-------SQAEGSPLRPRDRERSG---PESAATRAPRSEEDKRRAVIEKWVNGEYCEEP-APTPVLGRIVREG--SELPPEGVYMVQPQGCSDEEDHAEEPSKDNSILG---EKDSDG--TKDDSGPSAKQAS---------GEASSLRDYAASTMTEFLGMFGYDDQNTRDELARKISFEKLHAGSTPEVVASSMLPSSEDTLSKRARFSKYEEYIRKLKAGEQLPWPAHG------SKAEDRAGKEVVGPLPSLRLPSN----TAHLETKATILPLPSHSSVQMQNLVARASKYDFFIHKLKTGESLRPQNGSTYKKPSKYDLENVKYLHLFKPGEGSPDMGGAIAFKTGKVGRPSKYDVRGIQKPGTTKIPP--------APSLVPTPLTNVPSAPS----APGPGPEPPASLSFNTPEYLKSTFSKTDSITTGTVSTVKNGLPTDKPAVTEDVNIYQKYIARFSGSQHCGHIHCAYQYREHYHCLDPECNYQRFTSKQDVIRHYNMHKKRDNSLQHGFMRFSPLDDCSVYYHGCHLNGKSTHYHCMQVGCNKVYTSTSDVMTHENFHKKNTQLINDGFQRFRATEDCGTADCQFYGQKTTHFHCRRPGCTFTFKNKCDIEKHKSYHIKDDAYAKDGFKKFYKYEECKYEGCVYSKATNHFHCIRAGCGFTFTSTSQMTSHKRKHERRHIRSSGALGLPASLLGTKDTEHEESSNDDLVDFSALSSKNSSLSASPNSQQSSAS-----LAAAAAATTAEAVPSAAKPPNSKMAGLLPQGLSGSIPLALALSNSGLP-TTTPYFPLLPGRGSASLPVGSPGLLGSMTSGATTSATPDMP-ALMASGAGDSAPTAATSLSVPPASIMERISASKGLISPMMARLAAAALKPSATFDPGSGQQSTPTKFPQAQVKQEP-DSAGTPGPHEASQDRSLDLTVKEPSNESNGHAVPANSSLLSSLMNKMSQGNPSLGNLLNIKTEVEGSPAGEPS---PFLGKAVKALVQEKLSEPWKVYLRRFGTKDFCDAQCDFLHKAHFHCVVEECGALFSTLDGAIKHANFHFRTEGGTAKGTTEASFPTSAAETKPPLAPSSPPAPPGTMVPGSSLEGPAPSPVS-VPSTPTLLAWKQLASTIPQMPQIPSSVPHLPTSPLATTSLESAKPQVKPGFLQFQDNDPCLATDCKYASKFHFHCLFGNCKYVCKTSGKAESHCLDHINPSNSLVNVRDQFAYYSLQCLCPNQHCEFRMRGHYHCLRTGCYFVTNITTKLPWHIKKHEKAERRAANGFKYFTKREECG---RLGCKYNQVNSHFHCIREGCQFSFLLKHQMTSHARKHMRRMLGKNFDRVP-------------------PSQGPP----------SLMDAETDEGMDYTG-CSPGAASSESSTMDRSCSSTPVGNESTAAGC-------------PVPPPPPLPPPAAAGDEAARGAAPPTLTPSFPPAVLRPPLPPLPCLFSPSCLSYSLLSTTLGASRGLAHPISSPSSFPPITATPTPVKRDAPLVQDAAGNTISMPTASGAKKRFWIIEDMSPFGKRRKTASSRKMLDEGMMLEGFRRFDLYEDCKDTACQFS-LKVTHYHCTRENCGYKFCGRTHMYKHAQHHDRVDNLVLDDFKRFKASLSCHFADCPFSGTSTHFHCLR--CRFRCTDSTKVTAHRKHHGKQDVISAAGFCQFSSSADCAVPDCKYKLKCSHFHCTYPGCRHTVVGMSQMDSHKRKHEKQERGEPPAAS------------------------------------------------------------PGAPVSLDGSLTLAAEQGSLLFLQTAAAGLGL-LGDTGDPGPP-VTAPGTRDAPAAPAPVAAAAATTTTTTTTTTTSSAAGESSQEDDEEELEMPEEEAEEDDEDDDEEDDDDEDDDDDDDDEDLRTDS-EESLPEAAGEAG---ARTP----LAALGGPGPAPTAASP-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CWL2-1", "uniprot_id": "CASZ1_MOUSE", "id": "Q9CWL2-1", "name": "Zinc finger protein castor homolog 1", "aln": "-------------MDLGT-------------------AESTRCTDPPAGKPPMAAKRKGGLKLNAICAKLSRQVVVEKGAEAG-------SQAEGSPLHPRDKERSG---PESGVSRAPRSEEDKRRAVIEKWVNGEYCEDP-APTPVLGRIARD---QELPPEGVYMVQPQGCSDEEDHAEEPSKDNSVLE---EKESDGTASKDDSGPSTRQAS---------GETSSLRDYAASTMTEFLGMFGYDDQNTRDELAKKISFEKPHAGSTPEVAASSMLPSSEDTLSKRARFSKYEEYIRKLKAGEQLPWPAHG------SKAEDRAGKEVVGPLPSLRLPSN----TAHLETKATILPLPSHSSVQMQNLVARASKYDFFIHKLKTGENLRPQNGSTYKKPSKYDLENVKYLHLFKPGEGSPDMGGAIAFKTGKVGRPSKYDVRGIQKPGPTKIPP--------APSLVPTPLTNVPSAPS----TPGPGPEPPASLSFNTPEYLKSTFSKTDSITTGTVSTVKNGLPTDKPAVTEDVNIYQKYIARFSGSQHCGHIHCAYQYREHYHCLDPECNYQRFTSKQDVIRHYNMHKKRDNSLQHGFMRFSPLDDCSVYYHGCHLNGKSTHYHCMQVGCNKVYTSTSDVMTHENFHKKNTQLINDGFQRFRATEDCGTADCQFYGQKTTHFHCRRPGCTFTFKNKCDIEKHKSYHIKDDAYAKDGFKKFYKYEECKYEGCMYSKATNHFHCIRAGCGFTFTSTSQMTSHKRKHERRHIRSSGALGLPASLLGAKDTEHEESSNDDLVDFSALSSKNSSLSASPTSQQSSAS-----LAAAAAATTAEAIPSATKPPNSKMAGLLPQGLSGSIPLALALSNSGLP-TTTPYFPLLPNRGSASLPVGSPGLLGSMSSGATTSATPDMP-ALMASRAGDSAPTAATSLSVPPASIIERISASKGLISPMMARLAAAALKPSATFDPGSGQQPTPTKFPQAQVKQEP-DSAGTPGPHEASQDRSLDLTVKDPSNESNGHAVSANSSLLSSLMNKMSQGNPSLESFLSIKTEAEGSPAGEPS---PFLGKAVKALVQEKLSEPWKVYLRRFGTKDFCDAQCDFLHKAHFHCVVEECGALFSTLDGAIKHANFHFRTEGGTAKGTPEASFPTSAAETKPPLAPSSLPAPPGTMVAGSSLEGPAPSPVS-VPSTPTLLAWKQLASTIPQMPQIPSSVPHLPTSPLATTSLESAKPQVKPGFLQFQDNDPCLATDCKYASKFHFHCLFGNCKYVCKTSGKAESHCLDHINPSNSLVNVRDQFAYYSLQCLCPNQHCEFRMRGHYHCLRTGCYFVTNITTKLPWHIKKHEKAERRAANGFKYFTKREECG---RLGCKYNQVNSHFHCIREGCQFSFLLKHQMTSHARKHMRRMLGKNFDRVP-------------------PSQGPP----------SLMDAETDEGMDYTG-CSPGAASSESSTMDRSCSSTPVGNESTAAG-----------------------------------------------------------------------------------------------------------------NTISMPTASGAKKRFWIIEDMSPFGKRRKTASSRKMLDEGMMLEGFRRFDLYEDCKDTACQFS-LKVTHYHCTRENCGYKFCGRTHMYKHAQHHDRVDNLVLDDFKRFKASLSCHFADCPFSGTSTHFHCLR--CRFRCTDSTKVTAHRKHHGKQDVISAAGFCQFSSSADCAVPDCKYKLKCSHFHCTYPGCRHTVVGMSQMDSHKRKHEKQERGEPPAAS------------------------------------------------------------PGAPVNLDGSLTLAAEQGSLLFLQTAAAGLGL-LGDTGDPGPP-VTASGTRDGPAAPTPAAAATTTTTTTATATAT---AGESSQEDDEE-LELPEEEAEDDDEDDDEEDDDDEDDDDDDDDEDLRTDS-EESLPEAAGEAG---ARTP----LAALGGPGPAPTAAS--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86V15-1", "uniprot_id": "CASZ1_HUMAN", "id": "Q86V15-1", "name": "Zinc finger protein castor homolog 1", "aln": "-------------MDLGT-------------------AEGTRCTDPPAGKPAMAPKRKGGLKLNAICAKLSRQVVVEKRADAG-------SHTEGSPSQPRDQERSG---PESGAARAPRSEEDKRRAVIEKWVNGEYSEEP-APTPVLGRIAREG--LELPPEGVYMVQPQGCSDEEDHAEEPSKDGGALE---EKDSDGAASKEDSGPSTRQAS---------GEASSLRDYAASTMTEFLGMFGYDDQNTRDELARKISFEKLHAGSTPEAATSSMLPTSEDTLSKRARFSKYEEYIRKLKAGEQLSWPAPS------TKTEERVGKEVVGTLPGLRLPSS----TAHLETKATILPLPSHSSVQMQNLVARASKYDFFIQKLKTGENLRPQNGSTYKKPSKYDLENVKYLHLFKPGEGSPDMGGAIAFKTGKVGRPSKYDVRGIQKPGPAKVPP--------TPSLAPAPLASVPSAPS----APGPGPEPPASLSFNTPEYLKSTFSKTDSITTGTVSTVKNGLPTDKPAVTEDVNIYQKYIARFSGSQHCGHIHCAYQYREHYHCLDPECNYQRFTSKQDVIRHYNMHKKRDNSLQHGFMRFSPLDDCSVYYHGCHLNGKSTHYHCMQVGCNKVYTSTSDVMTHENFHKKNTQLINDGFQRFRATEDCGTADCQFYGQKTTHFHCRRPGCTFTFKNKCDIEKHKSYHIKDDAYAKDGFKKFYKYEECKYEGCVYSKATNHFHCIRAGCGFTFTSTSQMTSHKRKHERRHIRSSGALGLPPSLLGAKDTEHEESSNDDLVDFSALSSKNSSLSASPTSQQSSAS-----LAAATAAT--EAGPSATKPPNSKISGLLPQGLPGSIPLALALSNSGLP-TPTPYFPILAGRGSTSLPVGTPSLLGAVSSGSAASATPDTP-TLVASGAGDSAPVAAASVPAPPASIMERISASKGLISPMMARLAAAALKPSATFDPGSGQQVTPARFPPAQVKPEPGESTGAPGPHEASQDRSLDLTVKEPSNESNGHAVPANSSLLSSLMNKMSQGNPGLGSLLNIKAEAEGSPAAEPS---PFLGKAVKALVQEKLAEPWKVYLRRFGTKDFCDGQCDFLHKAHFHCVVEECGALFSTLDGAIKHANFHFRTEGGAAKGNTEAAFPASAAETKPPMAPSSPPVPPVTTATVSSLEGPAPSPAS-VPSTPTLLAWKQLASTIPQMPQIPASVPHLPASPLATTSLENAKPQVKPGFLQFQENDPCLATDCKYANKFHFHCLFGNCKYVCKTSGKAESHCLDHINPNNNLVNVRDQFAYYSLQCLCPNQHCEFRMRGHYHCLRTGCYFVTNITTKLPWHIKKHEKAERRAANGFKYFTKREECG---RLGCKYNQVNSHFHCIREGCQFSFLLKHQMTSHARKHMRRMLGKNFDRVP-------------------PSQGPP----------GLMDAETDECMDYTG-CSPGAMSSESSTMDRSCSSTPVGNESTAAG-----------------------------------------------------------------------------------------------------------------NTISMPTASGAKKRFWIIEDMSPFGKRRKTASSRKMLDEGMMLEGFRRFDLYEDCKDAACQFS-LKVTHYHCTRENCGYKFCGRTHMYKHAQHHDRVDNLVLDDFKRFKASLSCHFADCPFSGTSTHFHCLR--CRFRCTDSTKVTAHRKHHGKQDVISAAGFCQFSSSADCAVPDCKYKLKCSHFHCTFPGCRHTVVGMSQMDSHKRKHEKQERGEPAAEGPA----------------------------------------------------------PGPPISLDGSLSLGAEPGSLLFLQSAAAGLGLALGDAGDPGPPDAAAPGPREGAAAAAAAA-------------------GESSQEDEEEELELPEEEAEDDEDEDDDEDDDDEDDDEDDDDEDLRTDS-EESLPEAAAEAAGAGARTPALAALAALGAPGPAPTAASSP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B6A1-1", "uniprot_id": "A0A8M3B6A1_DANRE", "id": "A0A8M3B6A1-1", "name": "", "aln": "MKVTCLTGFNFDYPEYGTGRERAEAREKIEEEKTTCFAERSLCTEKTSGKSTMAAKRKGGLKLNAICAKLSRQVVYDGSSQNAEGDSDLVDNSERGSLHYDEGDRPESDFPEGLTLTQSLEEDQKRREAIEKWVNGEYGEDPQCLEGVEHRVLKPNNGEDGPPEGVYMVQPKGCSDEEDNAEEADTMPGSHEGSYHEDSEGSPRKDDSFQPTTEAPPRPAPFTPPGDSSALRDYAANTMNEFLNMFGYDDQQVRDELAKKISFEKLKAATS----DPSSLSSEE--ATRRARFSKYEEYIRKLKAGETLPWPVHTKPEVLNSKMTLTPEKSAALIQPTLTAGSEGQIFPPGMDHKQSSLNPAPTNQSHIQNLASRASKYDYFIQKLKMGESLREQNGNSYKRPSKYDLENVKFLHLFKPGEGNPDMGGAIAFKTGKVGRPSKYDIRNIQKLIPGKVDPPVLSSVLPATAGTPGPPVINTAAPAGVVGPPGLPMDQEGHLGFNT-DFMKSSFSKTDSITTGTVSSVKNGLPPEKPAT-EDVNVYQKYIARFSGSQHCGHVHCAYQYREHYHCMDPECNYQRFTSKQDVIRHYNMHKKRDNSLQHGFMRFSPLDDCSVYYHGCHLNGKSTHYHCMQVACNKVYTSTSDVMTHENFHKKNAQLINDGFQRFRAVEDCGTVGCQFYAQKTTHFHCRRPGCTFTFKNKCDIEKHKSYHIKDDAYAKDGFKKFYKYEECKYEGCVYSKATNHFHCIRQGCGFTFTSTSQMTSHKRKHERRHIRSSGVLGLTSSFLLPKE-EQDESSNDDLMDYSAISSKNSSLSASPTTQQSSTIPHLLPTPTTTMCSSQSVKPTAALPPASRISTLLSQALPSNVPMALALSNSALAGASNAFFPLIP-RMPMPLPPSAAGLISAATSVAHSMPSDSLPQTSTPTGDLAAATVASTPTSFAASSIMEKMSASKGLISPMMARLAAAALKPSGNPDAGMGQAG---QFNPVEVKQEPVDGAAS---QESIQEHSLDLSKKDHSAESNGHPAPGNTSLLSSLMNKMN---PGFFNALDLKSELEGAQAADGSDAAQYLSRVMKRSSPEKPTELWKTYLRRYDIDDFCEAHCDFLHKIHFHCLVEDCGALFSTVDGAIKHANFHFRAN---LKVKSEPPFNESKESNDS--GPNQMSAP-ISMAKTPPVEVPSLAVSGGYSSSPSFQAWKQLAGSIPQLPASMPSMP--ATSPLATTSLENAKPQVKPGFLQFQDNDPCLATDCKYSNKFHFHCLFGNCKYVCKTSGKAESHCLDHINPNNNLVNVRDQFSYYSLQCLCPNQHCEFRMRGHYHCLRPGCYFVTNITTKLPWHIKKHEKAERRAANGFKYFTKREECG---RHGCKYNQVNSHFHCIREGCQFSFLLKHQMTSHARKHMRRMLGKNFDRVPSQVVSHAHQPEEMQRMASLASSGMVGSHHNMNPNFSNMMEDNDDYMDYTAGGSPLGLSSESSNQDRSCTSTPVGNDSSPAGPGCQVPAPATTTSADSPPSQSAPPPPPPSLPPPHQPALQSQPPSLSSALLRPPLPSLPYLLSPSCLSYSLLSASLGATRSVVMPTN-TTAFSPIIPTSSSVKNDVPIVQDAAGNTISIPTATGAKKRFWIIEDMSPFGKRRKTASSRKMLDEGMMLEGFRRYDLYEDCKDTACQFS-LKVTHYHCTRENCGYKFCGRTHMYKHAQHHDRVDNLVLDDFKRFKSSLCCNFPDCQFSGNSTHFHCLR--CGFRCTDSTKVTAHRKHHGKQDVISAAGFCQFSSSVDCEVADCKYKLKCSHFHCTYPECKHTVVGMSQMDSHKRKHEKQERGELPSVSPNQDGNHHHHHHHHHHHAGLAIPSMPMNLPPTSPSTPGLTHNNMTMFHLPSTGAVNEYEHPGSAVNLDSSLNLGTDTNSSLFFLKNAAGLGL--SDSMDLSKKMHRDPLSLAPGSGPIASMG------------------LGNPQDDTTGTSGDLEDDLSPEEEPIAEDDDDDDDEEEDEAEDDMNTDSYEDSMPEPEVDKDNGESFDASMNHAETSQLDKEDPEAEP--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VTJ3-1", "uniprot_id": "Q9VTJ3_DROME", "id": "Q9VTJ3-1", "name": "C2H2-type domain-containing protein", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MESSSSVVAEMES--TSPSDHGQPTQ--------------ITSIDG------------------------FFNRKRGRPPKNRFVEVYKSAQHSPQAIFTSFK-LERSEYSGPGARLPG----------GSSSTVATAEDRLSLADHDGSATDLTPSRYR------------------------------------------------------------------------------------KRGRVWAPTSSLEQPSKRIVNQPTHFGAR-------------------------SETESRSSRHESLAQPTLQ--------------------------------------------------------------------------------------------------------------PSEPLETNSSTNLSSTILDKVSVVR----------AAGTFYPENANSAAQGETPEVVSSRYNSRQESN----------DLEVDQPEDLSMRPSLPEATATPAVVGPALNMNLL---------------------------------------------QFKQLIDLYQR--------------------------------------------------------------------------QVLLPSFLAAASQPLALPGSAAGP-GVSGPLLDMRILLENAAQQKLMLLNAAASATASAVAATTINSGQRTAAK------------------------------------------------------------------------------------------------------------RNRDHDIPSGYLKFRFNEDCG---FERCGYRNHQSHFHCNRRDCHYSFCDKTRFVQHTARHER--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDTLMGDDFRQFRANMQCGVASCGYA-TAS---------------GAATETNHLSRIDPTEAVTASSRK------------------TSHFHCRK--CDYVCTDSNKVVAHRRLHLRQDYVRNAGFRKVGGNEQCDSPGCSYAQRHTHYHCVT--CDGGVLSRAQLAAHKHRTGFPKQEADTTP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q7M3M8-1", "uniprot_id": "CAS_DROME", "id": "Q7M3M8-1", "name": "Transcription factor castor", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSNQMEFIMQLYMMNLMKQQQQMQLQLPQQQQQQ-----------------------------------------------------------------------------------------------QLAGYTYTQNEDISSSTSVQQQQQQQQE----------------------------------------------QLQQPQPDLRKTRTHKRISSQNTNCSSSRSCSPNSNLIAFQPQQYPG-------ATAATPSTPNSHPSNLVNQMLLQSLPPLTQLMLQQ-----------------------------------------------------------------------------QQQQHLLTTSNLLLTPTHTPSSLGKQDPLQHPLLLG----------------------QFAGSEQMATNNFLQSSTVTSTPIERE-----------------------------------------------------------------------------------------------------KAATPAPSAGATAGNLSAAQVKFEQESADDDEDDDKPLSSLTSCSSSGHTNASSEKLLLSGVHPLESTTDS------------LDSPSMYTPVKQPADSSYGLITPVDSDLTPNTP---------------------------------------------------------------------------------------------------------------------------------LQPTQTISLLTPPSSEQSKSLVSLSAASGLDALLQNEEVLKNLRKVSSYLECENSLCRQENLREHFHCHEEPCQGKILSKKDD--------------------------------------------------------------------------------------------IIRHLKWHKKRKESLKLGFARFSSSDDCAPAYGEGCAYNWKQTHYHCVYEHCPKVYVSTSDVQMHANFHRK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DSEIVNEGFRRFRAHETCRIEDCPFFGKKISHYHCCREGCTHTFKNKADMDKHKTYHLKDHQLKMDGFKKILKTEVCPFDACKFSTVCNHIHCVREGCDYILHSSSQMISHKRKHDRQDGEQAYQQFKIKQDVEESSLDAMPQQQQQQQQQQPTSLSQSQSSSSVCGGSNTSTPLSSLSAEHFLARKR---------------------------------------------------------GRPPKKIQLPADAQQSEAKRLKVEDESSNPAMLLPQSQPAAAVHPLTSGLFPGLLPAAAAPG---------------------VDPTAPNFQLTHLMALFQLQNPLFYQNLYPGMTQNSSMLGNLAALSAASAAAAAAAAANGAGVQQPKAEFSFKPEFKE---------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : .: : .: : : : : : .:. : : : * . .. : . : . . * : *.: .* . * . ::.: : . . . . .:: :. . :: : .. . .: . . . . . : .: . . .. * . . . . . . . : : : . . :. : .: .. *: * ::*. * *. ::*:** . * : . . *: * : . :: :.**:: * * : . : :* . : .. * .*:** : * : .*.:: :*:: * :** :. . : .. : : : . : . : . ", "identical_positions": 32, "similar_positions": 141, "identity": "1.54%" }, { "cls_id": "homologset.agr.MGI:1196252", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5RKG1-1", "uniprot_id": "SPICE_RAT", "id": "Q5RKG1-1", "name": "Spindle and centriole-associated protein 1", "aln": "MSLIRVNRFGPRGGARKTLKVKKK-AAVRQEWDNTVNDLTVHRATPEDLVRRHEMHKSKNRALVHWELQEKALKRKWKKQKPETSS-IEKRKLSIMKEILSDQYQTQDVLEKSDHLLTAAKGLFVDVPRKRTGFPNVTMAPGS---SRSPAGINQDPGTQS-ILNESIIEPQALNEVDDGGAESTAHSQSEDSESE--LPNSLSPHSNRNTERFLHQLKEENSELINQLWTDIQQKIAAQSQRTPPGSPSSELSAEDQKGALNATDAVKRIQAGLQPEESAEPVD--SSYVGQVLNTRKPKPLLSKVKRKQDMRALSKQKKNMLSSSTTSADLASSNNSSLDVLKHMIHEVEHEMEEYERWTGR--EVKGLQGGQGLTGFTLSLVSSLCRLVRYLKESETQLRKEVETRQQLEQMLGDHRELIDALTAEILLLREENGAVQARLQQYMVTTDEQLISLTHAIKSCPVINNSRQESQAPERAAMGRRLVDNVGAPVVNSNVSMPLMLKGEEMVDFPQEELPVKLSQGPPPTENLNLASNFPTHIFEPAVMLTPPRQKSNSEFSPLQDVLRRTVQTRPAPRIPPTVEVIEKEQTWEKKNLPIDPDIQNSSEESRLFTQRWRVSHMGDDLENKSQPQFVSLSQPPQFVSLSQPPCSSPPSTQQSRNPVFSEEPTVLGDGQQLGTADALMHRKDIMARIAELTLQNSAMKAHLNNITSSGGEHGDGLREPSRQGNASEVPANFPAVQSLMPSSMEERIAELNRQSMEARSKLLQLIEQQKLVGLTLSSSPVSPVESPLRAWTEEGKRTIEVSVPGVEASESSKCNTVSPVSGVSSRRSSGAISNSCSPLNATSGSGKFTPVNPRTKQTEKQSEEGWFALSAHLP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C804-1", "uniprot_id": "SPICE_MOUSE", "id": "Q8C804-1", "name": "Spindle and centriole-associated protein 1", "aln": "MSLIRVNRFGPRGGGRKTLKVKKK-AAVRQEWDNTVNDLTVHRATPEDLVRRHEMHKSKNRALVHWELQEKALKRKWKKQKPETSS-LEKRKLSIMKEILSDQYLTQDVLEKSDHLMAAAKGLFADVPRKRTGFPNVTRAPDS---SQSHTGINQDPVTQS-ILNESIIEPQALNEVDDAGEQSTAHSQSEDSENE--LPNSLSQHSNRSTERFLHQLKEENSELINQLWTDIQQKIATQSQRTPPGSPSSELSAEDQKAALNATDAVKRIQAGPQPEEAAEPVDFSSSYLGQVLNTRKQKPLLAKVKRKQDMHAASKQKTNMLSSSTASADRPSSTGSSLDVLKHVIHEVEHEMEEYERCTGR--EVTGLQGGQGLTGFTLSLVSSLCRLVRYLKESEIQLRKEVETRQQLEQMLGDHRELIDALTAEILSLREENSTMQARLQQYMVTTDEQLISLTHAIKNCPVINNSRQESQAPERAAMGRRLVDNVEGPVISSNGSMPLMFRGEEVVEFPQEELPVKLSQGPTPTENLNLANNFPTHIFEPAVMLTPPRQKSNSEFSPLQDVLRRTVQTRPAPRIPPTVEVIEKEQNWEKKALPIDPDIQNSSEENRLFTQRWRVSHMGEDLENKGQPAFVSLSQ---------PPCSSLPSTQQPRNPVLSEEPTVLGDGQQLRTSEALVQRKDIMARIAELTLQNSAIKAHLNNITSSGGEQGDGLREPRKQGSASEVSTNFPAVQSLTPSSMEERIAELNRQSMEARSKLLQLIEQQKLVGLNLSSSPVSPVESPLRAWAEEGKRTIEVSVPGMEASESSKCNTVSPVSGNSSRRSSGAISNSCSPLNATSGSGKFTPVNPRTK-TEKKNEEGWFALSAHIP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N0Z3-1", "uniprot_id": "SPICE_HUMAN", "id": "Q8N0Z3-1", "name": "Spindle and centriole-associated protein 1", "aln": "MSFVRVNRCGPRVGVRKTPKVKKKKTSVKQEWDNTVTDLTVHRATPEDLVRRHEIHKSKNRALVHWELQEKALKRKWRKQKPETLN-LEKRRLSIMKEILSDQYQMQDVLEKSDHLIAAAKELF---PRRRTGFPNVTVAPDS---SQGPIVVNQDPITQS-IFNESVIEPQALNDVD-GEEEGTVNSQSGESENENELDNSLNSQSNTNTDRFLQQLTEENFELISKLWTDIQQKIATQSQITPPGTPSSALSSGEQRAALNATNAVKRLQTRLQPEESTETLDS-SYVVGHVLNSRKQKQLLNKVKRKPNLHALSKPKKNISSGSTTSADLPNRTNSNLDVLKHMIHEVEHEMEEYERWTGR--EVKGLQSSQGLTGFTLSLVSSLCRLVRYLKESEIQLRKEVETRQQLEQVLGDHRELIDALTAEILRLREENAATQARLQQYMVTTDEQLISLTHAIKNCPVINN-RQEIQASESGATGRRVMDSPERPVVNANVSVPLMFR-EEVAEFPQEELPVKLSQVPDPPDNMNLAKNFPAHIFEPAVLLTPPRQKSNLKFSPLQDVLRRTVQTRPAPRLPPTVEIIEKEQNWEEKTLPIDTDIQNSSEENRLFTQRWRVSHMGEDLENKTQAPFVNLSQ---------PLCNSHSNTQQSRSPTFSEELPVLGDGQQLRTNESLIQRKDIMTRIADLTLQNSAIKAHMNNIIEPRGEQGDGLRELNKQESASDMTSTFPVAQSLTPGSMEERIAELNRQSMEARGKLLQLIEQQKLVGLNLSP-PMSPVQLPLRAWTEGAKRTIEVSIPGAEAPESSKCSTVSPVSGINTRRSSGATGNSCSPLNATSGSGRFTPLNPRAK-IEKQNEEGWFALSTHVS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A2R8Q094-1", "uniprot_id": "A0A2R8Q094_DANRE", "id": "A0A2R8Q094-1", "name": "Spindle and centriole-associated protein 1", "aln": "MSLVRINRPFYCAG--KRPIRTRKVSAPKKEWVSTVNDLSVHKATPEELARRHEMHRSQNRVVAQWELKEKTLTRRRRKNQPLSPPGLDRARRDIIREVFSDHCQLQDVIARSDRALAVVKDLFGDAPRRRTGFPSITVAPDCDSDSELPVHQKLDPPTQLSLLSQSMMDQQALNELEEHEEECDEVQDAS------------------------VHLKSVMHRKRNKCRPKSFPRGSDNHEQDLPQKPCTTG-VREDYAALNATVAVEQLKSR----QTHPGVNQSTSFVDQFLNPEPASSQHGVKNR--SVQASRGRSAHTSAMNSSGLHSLAGNQSSLELLQSMLEQVETELDSLDKQNPQSSETRPQQQRPGLTGFSVALLTTLRRLTSHIKKRDEESLRETRERRRLEDEVKEQRALIDALTVETLTLREESAALQARLQLQISDLEQRLNAVNLIAG--------RPDSAEPHR---TVQIIDN-----------------------------TTQRSSHLESEKDLQRQD-----FVSAAVLLSPPRQQDGHPHAAFRPHPHAASQLNSG-----SCAATGSQGSLEDFDISISPSS---------FASLPRPAHLLDDLSQDAMLEEIAELT---------------RQNAAIRAQLVQQRPSPAG---ASVSRELSAETFSTTSSVCRQTPHCTELQQTLQPVS----------------------------AERPSAMEIEQKLQELNRQSAEARAKLLELIEQQKQSTSIRASPAISPVPPPS-------SSTLTVKGFNPEPFLTLPERSHSPQLSASMQRSAGRVS----PHNSENGE------IPENQ-VEKLKRDGWFALSAHVK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**::*:** * * .:* :: ::** .**.**:**:****:*.****:*:*:**.:.:***:**:*.*: :*::* : ::: : .*::*::**: ***: :**: ::..* ** **:*****.:* **.. *. : ** ** ::.:*::: ****::: : .:: :*.. . .: .. : : : : * .*.: :: .***** **::::: :: :: : :.:.**.. . :* .::* . : : .::. . . *.*::*: ::.:** *::. :: . : *. * *****:::*:::* **. ::*: : : :*.. *::**: : ::* ******.* * ****..: ***** : :::* ::. * : .. :::*. ..: *. . .::: . :...**:*:****:.. .:.:: : : * ... : .: . *. :.*... *:. * :*: :**.:. : .. * ..:. . * : : . . : :. * : : :: :: : .: . .:*::: ****** ***.***:****** :. .:*** * . *: *. . *. : : ** . . :**:* . * *: .*. *. : ** ..:******:*: ", "identical_positions": 190, "similar_positions": 276, "identity": "21.59%" }, { "cls_id": "homologset.agr.MGI:1196256", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6G2K8-1", "uniprot_id": "KDM1A_RAT", "id": "A0A8I6G2K8-1", "name": "Lysine-specific histone demethylase 1A", "aln": "MLSGKKAAAAAAAAAAAAAG-TEAGPGAAGGAENGSEVAAPPAGLAGPADIATGAAGERTPRKKEPPR-ASPPGGLAEPPGSAGPQAGPTAGPGSATPMETGIAETPEGRRTSRRKRAKVEYREMDESLANLSEDEYYSEEERNAKAEKEKKLPPPPPQAPPEEENESEPEEPS---GVEGAAFQSRLPHDRMTSQEAACFPDIISGPQQTQKVFLFIRNRTLQLWLDNPKIQLTFEATLQQLEAPYNSDTVLVHRVHSYLERHGLINFGIYKRIKPLPIKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADLGAMVVTGLGGNPMAVVSKQVNMELAKIKQKCPLYEANGQA------VPKEKDEMVEQEFNRLLEATSYLSHQLDFNVLNNKPVSLGQALEVVIQLQEKHVKDEQIEHWKKIVKTQEELKELLNKMVNLKEKIKELHQQYKEASEVKPPRDIT-------AEFLVKSKHRDLTALCKEYDELAETQGKLEEKLQELEANPPSDVYLSSRDRQILDWHFANLEFANATPLSTLSLKHWDQDDDFEFTGSHLTVRNGYSCVPVALAEGLDIKLNTAVRQVRYTASGCEVIAVNTRSTSQTFIYKCDAVLCTLPLGVLK--------QQPPAVQFVPPLPEWKTSAVQRMGFGNLNKVVLCFDRVFWDPSVNLFGHVGSTTASRGELFLFWNLYKAPILLALVAGEAAGIMENISDDVIVGRCLAILKGIFGSSAVPQPKETVVSRWRADPWARGSYSYVAAGSSGNDYDLMAQPITPGPSIPGAPQPIPRLFFAGEHTIRNYPATVHGALLSGLREAGRIADQFLGAMYTLP----------------------RQATPGVPAQQSPSM-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6ZQ88-1", "uniprot_id": "KDM1A_MOUSE", "id": "Q6ZQ88-1", "name": "Lysine-specific histone demethylase 1A", "aln": "MLSGKKAAAAAAAAAAAAAAGTEAGSGAAGGAENGSEVAAPPAGLTGPTDMATGAAGERTPRKKEPPR-ASPPGGLAEPPGSAGPQAGPTAGPGSATPMETGIAETPEGRRTSRRKRAKVEYREMDESLANLSEDEYYSEEERNAKAEKEKKLPPPPPQAPPEEENESEPEEPS---GVEGAAFQSRLPHDRMTSQEAACFPDIISGPQQTQKVFLFIRNRTLQLWLDNPKIQLTFEATLQQLEAPYNSDTVLVHRVHSYLERHGLINFGIYKRIKPLPIKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADLGAMVVTGLGGNPMAVVSKQVNMELAKIKQKCPLYEANGQA------VPKEKDEMVEQEFNRLLEATSYLSHQLDFNVLNNKPVSLGQALEVVIQLQEKHVKDEQIEHWKKIVKTQEELKELLNKMVNLKEKIKELHQQYKEASEVKPPRDIT-------AEFLVKSKHRDLTALCKEYDELAETQGKLEEKLQELEANPPSDVYLSSRDRQILDWHFANLEFANATPLSTLSLKHWDQDDDFEFTGSHLTVRNGYSCVPVALAEGLDIKLNTAVRQVRYTASGCEVIAVNTRSTSQTFIYKCDAVLCTLPLGVLK--------QQPPAVQFVPPLPEWKTSAVQRMGFGNLNKVVLCFDRVFWDPSVNLFGHVGSTTASRGELFLFWNLYKAPILLALVAGEAAGIMENISDDVIVGRCLAILKGIFGSSAVPQPKETVVSRWRADPWARGSYSYVAAGSSGNDYDLMAQPITPGPSIPGAPQPIPRLFFAGEHTIRNYPATVHGALLSGLREAGRIADQFLGAMYTLP----------------------RQATPGVPAQQSPSM-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60341-1", "uniprot_id": "KDM1A_HUMAN", "id": "O60341-1", "name": "Lysine-specific histone demethylase 1A", "aln": "MLSGKKAAAAAAAAAAAATG-TEAGPGTAGGSENGSEVAAQPAGLSGPAEVGPGAVGERTPRKKEPPR-ASPPGGLAEPPGSAGPQAGPTVVPGSATPMETGIAETPEGRRTSRRKRAKVEYREMDESLANLSEDEYYSEEERNAKAEKEKKLPPPPPQAPPEEENESEPEEPS---GVEGAAFQSRLPHDRMTSQEAACFPDIISGPQQTQKVFLFIRNRTLQLWLDNPKIQLTFEATLQQLEAPYNSDTVLVHRVHSYLERHGLINFGIYKRIKPLPTKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADLGAMVVTGLGGNPMAVVSKQVNMELAKIKQKCPLYEANGQA------VPKEKDEMVEQEFNRLLEATSYLSHQLDFNVLNNKPVSLGQALEVVIQLQEKHVKDEQIEHWKKIVKTQEELKELLNKMVNLKEKIKELHQQYKEASEVKPPRDIT-------AEFLVKSKHRDLTALCKEYDELAETQGKLEEKLQELEANPPSDVYLSSRDRQILDWHFANLEFANATPLSTLSLKHWDQDDDFEFTGSHLTVRNGYSCVPVALAEGLDIKLNTAVRQVRYTASGCEVIAVNTRSTSQTFIYKCDAVLCTLPLGVLK--------QQPPAVQFVPPLPEWKTSAVQRMGFGNLNKVVLCFDRVFWDPSVNLFGHVGSTTASRGELFLFWNLYKAPILLALVAGEAAGIMENISDDVIVGRCLAILKGIFGSSAVPQPKETVVSRWRADPWARGSYSYVAAGSSGNDYDLMAQPITPGPSIPGAPQPIPRLFFAGEHTIRNYPATVHGALLSGLREAGRIADQFLGAMYTLP----------------------RQATPGVPAQQSPSM-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F6NIA2-1", "uniprot_id": "F6NIA2_DANRE", "id": "F6NIA2-1", "name": "Lysine-specific histone demethylase", "aln": "MLSNKKSDPGSSSS-----------SGGNGGDRAPETLAAPQAGPAGPS-------GPISADVKKKER-ASPSG---EPGGPPLPHP---PGPGGID------QDSAEGRRTSRRKRAKVEYREMDESLANLSEDEYYSEEERNAKAEKERKQVIPPPAPPIEEENDSEPEEPSGINGVEGAAFQSRLPHDRMTSQEAACFPDIINGPQHTQKVFLYIRNRTLQLWLDNPKVQLTFEATVQQLEAPYNSDAVLVHRIHSYLERHGFINFGIYKRVKPLPTKKTGKVIVIGAGVSGLAAARQLQSFGMDVTVLESRDRVGGRVATFRKGNYVADLGAMVVTGLGGNPMAVVSKQVNMELAKIKQKCPLYEANGQAGERCTSVPKEKDEMVEQEFNRLLEATSYLSHQLDFNFLNNKPVSLGQALEVVIQLQEKHVKDEQIEHWKKIVKTQEELKDLLNKMVTTKEKVKELHQQYKEASEVKPPRDIT-------AEFLVKSKHRDLTALCKEYDELVEMQVKLEERLQELEANPPSDVYLSSRDRQILDWHFANLEFANATPLSTLSLKHWDQDDDFEFTGSHLTVRNGYSCVPVALAEGLDIKLNTAVRQVRYTSSGCEVIAVNTRSTTQTFIYKCDAVLCTLPLGVMK--------QQPPAVQFVPPLPEWKTAAIQRMGFGNLNKVVLCFDRVFWDPSVNLFGHVGSTTASRGELFLFWNLYKAPILLALMAGEAAGIMENISDDVIVGRCLAILKGIFGSSAVPQPKETVVSRWRADPWARGSYSYVAAGSSGNDYDLMAQPITPGPAIPGASQPVPRLFFAGEHTIRNYPATVHGALLSGLREAGRIADQFLGAMYTMP----------------------RQATANPNPQPSPSIQ----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VW97-1", "uniprot_id": "LSDA_DROME", "id": "Q9VW97-1", "name": "Possible lysine-specific histone demethylase 1", "aln": "-MKPTQFGGSSSKMTEPIEYVTLISDDSDGEPTPKRNVNHPPSALSAPN------PGQKQKHPDEDSNDAPATSDERRTSRRNRPKVDYSNRPSGSG---DTASNDKSGSASMGPNNQQAERRSQSQTRK--SEANATSSSVSGPSAGNSR----PSQNGDSKDRDAGTPTVLS---GQEGAVFQSRLPFNKMTPNEEACFPDISRSGILGHRVFLNIRNSLLHMWVDNPKIQLSFEIALKNLPPPFDSEPSLVRRVHSFLERHGFINFGIFKRLKPIPAKKLGKVIVIGAGISGLAVAHQLQQFGMDVIVLEARDRVGGRISTFRKNSYIADVGAMVVTGVYGNPMTILSKQIGMDLVPIQQTCPLYGPDGKP------VPKEKDDVIEREFNRLLESASYLSHRLDFNYAGDCPVSLGDALEWIISMQEMQVMHKRGQHMQEIIATQTKIIEQRRRLKTLRDTIGKLKNEHLAMINQRKPKGTDGDLKYCYQEFNIRNTQIKMEETISTFHDLHAEEKQMLAKLHELEQNRPSDVYLSSRDRLILDWHFANLEFANATRLNNLSLKHWDQDDDFEFIGHHTTVRNGYSCVPVALTENLDIRVNSAVKEIKYGTKGVEVVAENLKTSNSQMTYKADLVVCTLTLGVLKVAVAHKESQQSNTVKFDPPLPDWKQQAIKRLGFGNLNKVVLCFDRIFWDPNANLFGHVGSTTASRGEMFLFWSISSSPVLLALVAGMAANLVESVTDDIIIGRCMSVLKNIFGNTSVPQPKETVVTRWRSDPWARGSYSYVSVGSSGSDYDLLAAPVIP-PSSKDAEG-LPRLFFAGEHTIRNYPATVHGAYLSGLREAGRIADYYLGYPEGTPPDIGYSVAEAANLVSVGNVVKLRDLSPNLSDSSPSSKKSEENSNSNTADSTELQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. .: .:: . * : :. :.* * .: . *.... .. *: *.. : .* : :. :.* *. .:: ** : *.. ...* :.: *. ::.: . * * * ***.******.::**.:* ****** . ::*** *** *::*:****:**:** ::::* .*::*:. **:*:**:*****:*****:**:**:* ** ****:**:*:****.*:***.***** :**:*******::****..*:**:*******: ****:::***:.*:*. *:*.**** .:*:. ******:::*:*******::*****:**** .: *****:*** :*.:** :* .:: :* ::*: ** :: : .:: . ::.: :*:::: : : *:. ** ::..: .: . :.:* : :: :*:*** * *********** *************** *..************** * * *************:*.***::*:**::::* :.* **:* * :::.. : **.* *:***.***:* **. :*:* ****:** *::*:**************:****..***************:****.: .:*:****:** **.::*.::**:*:***:::**.***.::*********:***:***********:.****.****:* *: * *: .* :********************* ************ :** * *: :.. . ..* ", "identical_positions": 408, "similar_positions": 240, "identity": "44.49%" }, { "cls_id": "homologset.agr.MGI:1196259", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O43508-1", "uniprot_id": "TNF12_HUMAN", "id": "O43508-1", "name": "Tumor necrosis factor ligand superfamily member 12", "aln": "--MAARRSQRRRGRRG------------EPGTALLVPLALG----LGLALACLGLLLAVVS-LGSRASLSAQEPA--QEELVAEEDQDPSELNPQTEESQDPAP---------------FLNRLVRP--------RRSAP-----KGRKTRARRAIAAHYEVHPRPGQDGAQAGVDGTVSGWEEARINSSSPLRYNRQIGEFIVTRAGLYYLYCQVHFDEGKAVYLKLDLLVDGVLALRCLEEFSATAASSLGPQLRLCQVSGLLALRPGSSLRIRTLPWAHLKAAPFLTYFGLFQVH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O54907-1", "uniprot_id": "TNF12_MOUSE", "id": "O54907-1", "name": "Tumor necrosis factor ligand superfamily member 12", "aln": "--MAARRSQRRRGRRG------------EPGTALLAPLVLS----LGLALACLGLLLVVVS-LGSWATLSAQEPS--QEELTAEDRREPPELNPQTEESQDVVP---------------FLEQLVRP--------RRSAP-----KGRKARPRRAIAAHYEVHPRPGQDGAQAGVDGTVSGWEETKINSSSPLRYDRQIGEFTVIRAGLYYLYCQVHFDEGKAVYLKLDLLVNGVLALRCLEEFSATAASSPGPQLRLCQVSGLLPLRPGSSLRIRTLPWAHLKAAPFLTYFGLFQVH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZXQ2-1", "uniprot_id": "A0A8I5ZXQ2_RAT", "id": "A0A8I5ZXQ2-1", "name": "Tumor necrosis factor ligand superfamily member 12", "aln": "HAPGHRTPLSCKALRGGWSLITQTVSGFLSSSAPLRPASLVPPSPLARSAHQLPLPIPRVPGWGGGEAGTAPRPHGRPSEPEAEGAPGGAGHRPAGPAGAEPGPGVGLPWPPAGRGQPGELGNAVCPGAFSGGADSRGPPGAPFSKGRKARPRRAIAAHYEVHPQPGQDGAQAGVDGTVSGWEETKINSSSPLRYDRQIGEFTVIRAGLYYLYCQVHFDEGKAVYLKLDLLVNGVLALRCLEEFSATAASSPGPQLRLCQVSGLLPLRPGSSLRIRTLPWAHLKAAPFLTYFGLFQVH", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * . :. ** ..:* * * * *. : * * : *. *. : :* .* .* ** . .* . : * * . * * *..* ****:*.************:*******************::*********:****** * ***************************:****************** *************.********************************", "identical_positions": 166, "similar_positions": 31, "identity": "55.7%" }, { "cls_id": "homologset.agr.MGI:1196260", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5BK20-1", "uniprot_id": "JUPI2_RAT", "id": "Q5BK20-1", "name": "Jupiter microtubule associated homolog 2", "aln": "-----MFRGADGQASKSGFRSMKPPGGESNDIFGSPEEGVPSSK-PHRMASNIFGPTEEPKNIPKRTNPPGGKGSGIFDESTPVQTRQRLNPPGGKTSDIFG-SPVTATAPLAHPNKPKDHVLLCEGEDCKSDLKAATN------------STPRGEQGEKGSSTEAEPAKIPEPI----------PTVDSHEPRLGPRPRSHNKVLNPPGGKSSISFY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PGH2-1", "uniprot_id": "JUPI2_MOUSE", "id": "Q6PGH2-1", "name": "Jupiter microtubule associated homolog 2", "aln": "-----MFQGADSQAGKSGSRSMKPPGGESSDLFGSPEEGISSSK-PNRMASNIFGPTEEPKNIPKRTNPPGGKGSGIFDESTPVQTRQRLNPPGGKTSDIFG-SPVTATAPLAHPNKPKDHVLLCEGEDSKSDLKAATD------------STPRGEQSDKGSSKEVEHAKIPEPT----------PTVDSHEPRLGPRPRSHNKVLNPPGGKSSLSFY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZDL0-1", "uniprot_id": "D3ZDL0_RAT", "id": "D3ZDL0-1", "name": "", "aln": "-----MFQGMDGQAGRLGSRSIKLPGGESSNPFGSP----STSK-PYRMASNIFGPPEEPKNIPKRTNPPGGKGSGIFDESTPVQTRHRPNPPGGKTSDIFG-SPVTATMPLAHPNKPKDHVLLCEGEDCKPDWKASTY------------SAPRRE-----------HAKKPEAT----------PTVDSHEPRLGPRPRSHNKVLNPPGGKSSISFY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H910-1", "uniprot_id": "JUPI2_HUMAN", "id": "Q9H910-1", "name": "Jupiter microtubule associated homolog 2", "aln": "-----MFQVPDSEGGRAGSRAMKPPGGESSNLFGSPEEATPSSR-PNRMASNIFGPTEEPQNIPKRTNPPGGKGSGIFDESTPVQTRQHLNPPGGKTSDIFG-SPVTATSRLAHPNKPKDHVFLCEGEEPKSDLKAARS------------IPAGAEPGEKGSARKAGPAKEQEPM----------PTVDSHEPRLGPRPRSHNKVLNPPGGKSSISFY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1Q6E4-1", "uniprot_id": "F1Q6E4_DANRE", "id": "F1Q6E4-1", "name": "", "aln": "MTSTNMFQGLEAS-GKSSSRVLRPPGGGSSNIFGGYEEDSSASRRPNKMSSSIFAPPEKQQESPKRSNPPGGKSSGIFEKPEAALPQSKPVFSAAASSNIFGGAESTPPSLKSHPNKPKDNLSVGVPATPDPPAPVAKPEPVVVEEVKVQPVAPQPTPEKEPAAAAAAPAPAPPPANQKAEPATRQPSEKDHEPRLAPVPRSHNKVLNPPGGKSSVVFY", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **: :.. .: . * :: *** *.: **. .:*: * :*:*.**.*.*: :: ***:******.****::. .. .: : ... :*:*** : *.. :*******:: : .. .: .. * . *: ..*****.* ****************: **", "identical_positions": 68, "similar_positions": 57, "identity": "31.05%" }, { "cls_id": "homologset.agr.MGI:1196261", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5U2R4-1", "uniprot_id": "TM10C_RAT", "id": "Q5U2R4-1", "name": "tRNA methyltransferase 10 homolog C", "aln": "------MNVTVRFLRPFARYLVPYTFHRTRSNSYSRVLQRYVSSKVPSLPCHNKDSTSPPEQLELDGWKTTMKS-SIQENGVSVVSD-KDEDSLAATRELIEMWRLLGKEVP--EHITEEELKTLMECASKSAKKKYLRYLYGKEMMKKAKQMKKEMKAAAREEAKRARSLEPSTGEE-----QRDFMFLRLWDRQTNIALGWKGVQAMQFGQPLVFDMAYDNYMKPSELQNTVSQLLESEGWNRRNVDPFHIYFCNLEVDGAYHRELVKRY-GEKWDKLLLTATEKSPVDLFPKDSIIYLTADSPNVMTTFKHDKIYIIGSFVDKNTQTGTSLAKAKRQNLATECLPLDKYLQWDVGN-KNLTLDQMIRILLCLKNTGNWEEALKFVPRRKHTGYLEVPEHSQAAFRKLKKTKTLNSFRKGSLNVHMWKR-------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UFY8-1", "uniprot_id": "TM10C_MOUSE", "id": "Q3UFY8-1", "name": "tRNA methyltransferase 10 homolog C", "aln": "------MNVTVRFLRPFARCLVPYTFHRKRSHLYSGVLQRYMSSKAPSLSCHNKDSASPPEQLELDGWKATMKS-SIQEDGVSEVSD-KDEDSLASTRELIEMWRLLGKEVP--EHITEEDLKTLMECASKSAKKKYLRYLYGKEKAKKAKQVKKEMKAEAREEAKRARLLETTAEEQ-----QQDFMFLRLWDRQINIALGWKGVQAMQFGQPLVFDMAYDNYMKPSELQNTVSQLLESEGWNRRNVDPFHIYFCNLKIDSAYHRELVKRY-REKWDKLLLTATEKSPVDLFPKDSIIYLTADSPNVMTTFKHDKIYIIGSFVDKNTQTGTSLAKAKRLNIATECLPLDKYLQWEIGN-KNLTLDQMIRILLCLKNTGNWEEALKFVPRRKHTGYLEVSEQSQELVRKLKKTKTLNSFRKGSLNVRTWKR-------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7L0Y3-1", "uniprot_id": "TM10C_HUMAN", "id": "Q7L0Y3-1", "name": "tRNA methyltransferase 10 homolog C", "aln": "MAAFLKMSVSVNFFRPFTRFLVPFTLHRKRNNLT--ILQRYMSSKIPAVTYPKNESTPPSEELELDKWKTTMKS-SVQEECVSTISSSKDEDPLAATREFIEMWRLLGREVP--EHITEEELKTLMECVSNTAKKKYLKYLYTKEKVKKARQIKKEMKAAAREEAKNIKLLETTEEDK-----QKNFLFLRLWDRNMDIAMGWKGAQAMQFGQPLVFDMAYENYMKRKELQNTVSQLLESEGWNRRNVDPFHIYFCNLKIDGALHRELVKRY-QEKWDKLLLTSTEKSHVDLFPKDSIIYLTADSPNVMTTFRHDKVYVIGSFVDKSMQPGTSLAKAKRLNLATECLPLDKYLQWEIGN-KNLTLDQMIRILLCLKNNGNWQEALQFVPKRKHTGFLEISQHSQEFINRLKKAKT-----------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B8JM40-1", "uniprot_id": "B8JM40_DANRE", "id": "B8JM40-1", "name": "tRNA methyltransferase 10 homolog C", "aln": "------MMFLRWCFPPVRRMCVCQQIS----------VRSFSSSRT-----LLKDDPQHEEKLDLDIWKSVMRAQALPEDPPHLQDSTSAASVLEAHRELVETWHQAGKLVP--KVITDQQLQELSILTTKSSKKKYLKFLAIKEAQKNNDKRKQEKKRAEREAGKLQNNNGEEEEEERAA-GPENTFMLRLRNNSIESAHNWRTAQAMRFDQPLVFDMSYDQQMSRHELENTVSQLLESEGFNRRVQEPFHLHFCNLQPGGAYHRELLRRYGDETWRRLLITHTERSPLELFPHQDLVYLTADSRSVLRTFDHTKVYIVGAMVDRSIRVGASLAIAKRFRLATARLPLDEYLDWDCGA-KNLTLDQMIRILTTVKQTGCWQKALEFVPKRKHKGFHQQSGDKRSQKKHRGGADRAPWWSQQKQHQQK----------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7JUX9-1", "uniprot_id": "MRRP1_DROME", "id": "Q7JUX9-1", "name": "Mitochondrial ribonuclease P protein 1 homolog", "aln": "------------MLKHFARWRLGSQLLKG----------CAAPVRQASKTSSAENLIAGTEEPQKKFVNPFSQPAPALSNDTISENKEERDKRLKVLQLEADIAHQEGRRVPSLEFFKDHHWEHVLTLPTKSARIKYFGYLWQIEMKKEADQRKKAERAKEAERRVAEMRKEREENTHIIYGLGHTSLFLRIYDTTINHWQNNRLTRAMQFAPKMVLDCSYDEHMNNREATYAAKQLMMCFAENRMNDEPFDLHYCNTQMDSRCMQSLQRYIPTMHNPEFPINLHSKCFTELFPKQNLVYLTPHCREDLVTYNPDDIYIVGAMVDTMNNEPLSLAKAKRLGLRMARLPLDRYLQWGSGSGKSLTLNQMINIMLDLKKTGDWDTALKHVPRRKVVQNEFQPRREKDHWSTGTRARKLNMRIDHLFDFDENRRQATSYATPQNVRQRREGLEFQLDTWATGKQKKKQRQN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . * : : . : :: *: : . :. :. . .: .. . . * : : : *: ** : :.:.. : : ::::: **: :* * *: : *: : * . . ::**: : : . : .:**:* :*:* :*:: *. * :..**: . . ** :**.:::** : .. :.* : .: :. .:. :***::.::***... . : *: .:*::*::** . *** *** : ****.**:* * *.***:***.*: :*:.* *: **:.**:** . .: : ", "identical_positions": 74, "similar_positions": 124, "identity": "15.81%" }, { "cls_id": "homologset.agr.MGI:1196274", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AXW0-1", "uniprot_id": "BOREA_RAT", "id": "Q6AXW0-1", "name": "Borealin", "aln": "MAPKKRSSRGTRTNTLRSRKLASFLKDFDREVQVRTKQIESDRQTLLKEVENLYNIEVLRLPKALQVMKWLDYFALGGNRQALEEAATADRDITEINNLTAEAIQTPLKSVKKRKVIEVDEAIKEEEEDEEEEGGGGGGR--KSHKNLRSARVKRCPPSKKRTQSIQGRS-RSKRLS-HDFVTPAMSRLEPSLVKPTPGMTPRFDSRVFKTPGLRTPAAKEQVYNISINGSPLADS-KEISLSVPIGGGASLRLLASDLQRVDIAQLNPEALGNIKKLSSRLAQICSSIRTGR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BHX3-1", "uniprot_id": "BOREA_MOUSE", "id": "Q8BHX3-1", "name": "Borealin", "aln": "MAPKKRSSRGTRTNTLRSRKLASFLKDFDREVQVRTKQIESDRQTLLKEVENLYNIEILRLPKALQGMKWLDYFALGGNKQALEEAAKADRDITEINNLTAEAIQTPLKSVKKRKVIEVEESIKEEEE-EEEEGGGGGGRTKKSHKNLRSAKVKRCLPSKKRTQSIQGRG-RSKRLS-HDFVTPAMSRLEPSLVKPTPGMTPRFDSRVFKTPGLRTPAAKEQVYNISINGSPLADS-KEISLSVPIGGGASLRLLASDLQRIDIAQLNPEALGNIRKLSSRLAQICSSIRTGR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q53HL2-1", "uniprot_id": "BOREA_HUMAN", "id": "Q53HL2-1", "name": "Borealin", "aln": "MAPRKGSSRVAKTNSLRRRKLASFLKDFDREVEIRIKQIESDRQNLLKEVDNLYNIEILRLPKALREMNWLDYFALGGNKQALEEAATADLDITEINKLTAEAIQTPLKSAKTRKVIQVDEMIVEEEEEEENE-----------RKNLQTARVKRCPPSKKRTQSIQGKG-KGKRSSRANTVTPAVGRLEVSMVKPTPGLTPRFDSRVFKTPGLRTPAAGERIYNISGNGSPLADS-KEIFLTVPVGGGESLRLLASDLQRHSIAQLDPEALGNIKKLSNRLAQICSSIRTHK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5XLR4-1", "uniprot_id": "BORE1_DANRE", "id": "Q5XLR4-1", "name": "Borealin", "aln": "MAPRKRTQNAKSKKNPKAPKLEAFLLDFDDEVHTIVERLKEKTNNLLKDADNLYKTALIKLPMAVRKMNWIEYCNLEKPKSPVDDS-----------KVREEAAQVELAIAGNHTIPKVAAKEAKSSANSEDENMAPLKS---TMKKKKASKKAPSTSKKPRTLSISKQGGTIQRTTRKPLITPARSFLDSSIIGATPLITPRFDPRLPKTPALRSALHREKVYSMSVNGSPLSAGGEDIVISVPIGNGECIQLLASEMDSVDLSQLDEKALRSIRNLQNRLTTLCGSSK---", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***:* :.. .:. : ** :** *** **. ::::.. :.***:.:***: :::** *:: *:*::* * :..:::: :: ** *. * . .:.: :* :.. .*:* *: :::: . ..* ** **. :. :* : :*** . *: *:: .** :*****.*: ***.**:. *::*.:* *****: . ::* ::**:*.* .::****::: .::**: :** .*::*..**: :*.* : ", "identical_positions": 85, "similar_positions": 108, "identity": "29.01%" }, { "cls_id": "homologset.agr.MGI:1196275", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35778-1", "uniprot_id": "KLRD1_RAT", "id": "O35778-1", "name": "Natural killer cells antigen CD94", "aln": "MAVSRITRWRLMSMFFGIKCLFLIVALG---VLVKNSFTIQNIQSTPSSTPIVEFQKVSKCCACLEKWIGHQCSCYFISKEEKSWKGSREFCASQNSSLLQLQTRNE---------LSFMSSSQAFFWIGIHYNEERSAWLWED-GTFPSKDLFP----------EFSKFRQDHCIGYSISRE--ISSESCENKNRFICKQLPT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O54707-1", "uniprot_id": "KLRD1_MOUSE", "id": "O54707-1", "name": "Natural killer cells antigen CD94", "aln": "MAVSRITRWRLMSVIFGIKCLFLMVTLG---VLLINSFTIQNIQSTPSPTTTVEFQEVSECCVCLDKWVGHQCNCYFISKEEKSWKRSRDFCASQNSSLLQPQSRNE---------LSFMNFSQTFFWIGMHYSEKRNAWLWED-GTVPSKDLFP----------EFSVIRPEHCIVYSPSKS--VSAESCENKNRYICKKLPI-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13241-1", "uniprot_id": "KLRD1_HUMAN", "id": "Q13241-1", "name": "Natural killer cells antigen CD94", "aln": "MAVFKTTLWRLISGTLGIICLSLMSTLG---ILLKNSFTKLSIEPAFTPGPNIELQKDSDCCSCQEKWVGYRCNCYFISSEQKTWNESRHLCASQKSSLLQLQNTDE---------LDFMSSSQQFYWIGLSYSEEHTAWLWEN-GSALSQYLFP----------SFETFNTKNCIAYNPNGN--ALDESCEDKNRYICKQQLI-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "M9PFV8-1", "uniprot_id": "M9PFV8_DROME", "id": "M9PFV8-1", "name": "", "aln": "-MCGSHKMWCCQVFILALFAHTIAVEFHGSAARAEINFEGPSPAHSQDTAAPTSRPKRRVYALCPPKFHRVGTDCYSLVDQRSSWLEAHFFCKDKNANLTEPGKHADRKLRLFLQKQDALSGENDPIWLGATYDHHNNRWQWSMSGRNLSTDSFSRTDSAYVQLISNSQPLDNNCAIYDPSLKYRWSARPCSDKLRFICQHKMPKVSGPNRYKIYNRWNATYPNEQANEVVLEILEPRENDRRYHRRVKAEDSDEEMIIPDRRRNNNRRNNHRNRQIKNQNQHPNDVNYQPAQQRQRNRPRTSTVAPTTTQSVSQSNDVLAPSPTPQQMTQYDRKLQRQRERERRRQLRRQERQKLAREQKRERQRRLKEERQRLQREEQQRRQRLHHDEPKPQVNPQVKPQVIDELRQRSGEDLDKNQTDEHEQKLRNEQEKKLREEQQKQRDEQEQKDREEQDRLKQEEEQARTHQKELKENQEQQLRELKAKQEREKQERDYQQQKREHELELLKQRQAEADRQHAADEEAEKLRLERIQKQRELEAQQRREREEQRRKQREEQEEQDRQNHAKRLAEEKRLHDLYAERIRLANTEREKQLAEAHEAKRLEELKLQEQLKKQEDERQEQIRREQEEEEKRLELERLEEARRFEEKELKRLHEENQRREEQKLQREREIALREAAEKKLAEEEEMLRKEVAEEERKVKQRLEDEMRQAEEARKAKEAEERAAEEAKAAEQKRRVEAAKKKADEEVKAKLEEKRREYVTRISALSPEDQKKFIEMRKRRKQLKEKKERDQRAKELKRIQQAMRLDDNE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * :.: . : : .* . : . . . : . * *: .** : .:..:* :: :* .:::.* : . : . :. .: *:* *..... * *. * * *. . . .:* *. . . ..*.:* *:**:: ", "identical_positions": 24, "similar_positions": 61, "identity": "2.97%" }, { "cls_id": "homologset.agr.MGI:1196277", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZBW3-1", "uniprot_id": "D3ZBW3_RAT", "id": "D3ZBW3-1", "name": "", "aln": "MEGVSALLASCPTAGLAGGLGVTACAAAGVVLYRIARRVKP-THTMVNCWFCNHDTLVPYGNRNCWDCPHCEQYNGFQENGDYNKPIPAQYMEHLNHVVSSVPSPRDPAQ--------PQQWVSSQVLLCRKCSHHQTTKIKQLAAFTPREEGRYDEEIEVYRHHLEQMYKLCRPCQAAVDYYIKHQN-RQLRALLLSHQFRR-REVDQAHGQSFSSS--AMKAPFQVILLRALAFLACAFLLSTALYGPGE--PFTPGAALPPALPPGGNSSAASDN-ATSQA----EGWQQLLGLLPEHATEKLHEAWAFGQSHQTGIVAVGLLTCLLAMLLAGRIRLRRIDAFSTCLWALLLGLHLAEHYLQAASPGWLDTLKFSTTSLCCLVGFTAAVATRKATGPRRFRPRRYFSGDSASLFLSSPSLAVPYPSVTASPASLFIPTPP-GFLPLSKQQLFRSPRRVSPSSLPGRLSRALSLGTIPSLTRTDSGYLFSGSRPPSRVSPAGEVSLSDYFSLLSSSFPSSPLPSPAPS--VASSVASSSGSLRHRRPLISPARLNLKGQKLLLF-SPPGEAPNTPSSS---EEHSPPNGSLF-IDPPQLLQRNRTRDTKHTVDTRSMLARDSAHSGHSIKKEDESSQSST-CIVDTTTKGCSEETTPWKARVSPSLVRGLLAVSLAVNALFTSAYLYQNLR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2A8U2-1", "uniprot_id": "TM201_MOUSE", "id": "A2A8U2-1", "name": "Transmembrane protein 201", "aln": "MEGVSALLASCPTAGLAGGLGVTACAAAGVVLYRIARRVKP-THTMVNCWFCNHDTLVPYGNRNCWDCPHCEQYNGFQENGDYNKPIPAQYMEHLNHVVSSVPSPRDPAQ--------PQQWVSSQVLLCRRCSHHQTTKIKQLAAFTPREEGRYDEEIEVYRHHLEQMYKLCRPCQAAVEYYIKHQN-RQLRALLLSHQFRR-READQAHGQSFSSS--AVKAPFQVILLRALAFLACAFLLFTTLYGPSE--PFTPGAALPPALPPGGNSSAASDN-TTSQA----EGWQQLLGLLPEHATEKLHEAWAFGQSHQTSIVAVGLLTCLLAMLLAGRIRLRRIDAFSTCLWALLLGLHLAEHYLQAASPGWLDTLKFSTTSLCCLVGFTAAVATRKSTGPRRFRPRRYFSGDSASLFPSSPSLAVPYPSVTSSPASLFIPTPP-GFLPLTKQQLFRSPRRVSPSSLPGRLSRALSLGTIPPLTRTDSGYLFSGSRPPSRVSPAGEVSLSDYFSLLSSSFPASPLPSPAPS--VASSVASSSGSLRHRRPLISPARLNLKGQKLLLF-SSPGEAPNTPSSS---EEFSPPNGSLF-IESPQLPQRNHTRDTKHTMEMRSMLARDSARSSHSIKKEDESSQSST-CVVDTTTKGCSEETTPWKARVSPSLVRGLLAVSLAVNALFTSAYLYQSLR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5SNT2-1", "uniprot_id": "TM201_HUMAN", "id": "Q5SNT2-1", "name": "Transmembrane protein 201", "aln": "MEGVSALLARCPTAGLAGGLGVTACAAAGVLLYRIARRMKP-THTMVNCWFCNQDTLVPYGNRNCWDCPHCEQYNGFQENGDYNKPIPAQYLEHLNHVVSSAPSLRDPSQ--------PQQWVSSQVLLCKRCNHHQTTKIKQLAAFAPREEGRYDEEVEVYRHHLEQMYKLCRPCQAAVEYYIKHQN-RQLRALLLSHQFKR-READQTHAQNFSS---AVKSPVQVILLRALAFLACAFLLTTALYGASG--HFAPGTTVPLALPPGGNGSATPDNGTTPGA----EGWRQLLGLLPEHMAEKLCEAWAFGQSHQTGVVALGLLTCLLAMLLAGRIRLRRIDAFCTCLWALLLGLHLAEQHLQAASPSWLDTLKFSTTSLCCLVGFTAAVATRKATGPRRFRPRRFFPGDSAGLFPTSPSLAIPHPSVGGSPASLFIPSPP-SFLPLANQQLFRSPRRTSPSSLPGRLSRALSLGTIPSLTRADSGYLFSGSRPPSQVSRSGEFPVSDYFSLLSGSCPSSPLPSPAPS--VAGSVASSSGSLRHRRPLISPARLNLKGQKLLLFPSPPGEAPTTPSSS---DEHSPHNGSLFTMEPPHVPRKPPLQDVKHALDLRSKLERGSACSNRSIKKEDDSSQSST-CVVDTTTRGCSEEAATWRGRFGPSLVRGLLAVSLAANALFTSVFLYQSLR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A4IG66-1", "uniprot_id": "TM201_DANRE", "id": "A4IG66-1", "name": "Transmembrane protein 201", "aln": "MEALNQILIEYPPL-VVGGVGATAVAAGGALIYRIATRKKP-THLQVNCWFCNQDTVVPYGNRNCWDCPYCEQYNGFQENGDYNKPIPAQYMEHLNHGVSAG--VPETPK--------TLQWVNCQMLLCKKCNNNQTLKIKQLASFIPREDENYDEEIEVYKHHLEQTYKLCRPCQTAVEYYIKHQN-RQLRALLFNHQLRRTRDADKAFIKNTYS----LSTPAWLILLRILTFLACAFLVAVALSGYVDESPSVTQTLSGGVVPPKRVLQNENESKTDEGS----LMWDDLMGLLPEKAVENARLFWQSGSDHQMAVASVGLLTCITGVLMAGPVRLRRIDAVASVLWLLVICFYLAECYLKTDVPSWLEMVKFGITSVCCLVGFAAAVATRKSTSQRRARGRRYLSGGSPGEFFCN---HGPLLSAPVSESSTFIPTPPPNLSQLLIRQQSQRTRKASPSSLPGRLNRALSLGTIPSLARADSGFLFSGSRPSSQCKDS---PPSDYYSLKSGSRPSSPGPSPTPS--VAGSVTSTSSSARQRRPLISPARLNISGQKLRLF-SSPLEPFSLASPPPFLSEHNPMHSRGFLPDVPHFHLQNHG----------SVIDEGSVF-EHLEKPMGSSSSSSN-CHVDTTTGNNIESKPGWKGFLGMTLWPGLLFASLTINLSFICIYVYYNWR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1ZBL2-1", "uniprot_id": "A1ZBL2_DROME", "id": "A1ZBL2-1", "name": "Ima1 N-terminal domain-containing protein", "aln": "------MLTLLIRLAATAIPVCAILFVAGTFLFKVYISIRSRYDARVNCWFCNGNVRVPYQDRNSWTCPSCEQYNGFTKDGDYNRDITSQRDCSLGSQKNSSKGSSSICANSYYSDVLTAQPPAPKNGLCDQCNEAQRLKVEKLSQFEPKNESRFDQELKVYRERLEKQFRLCSSCERHVNKVLHEKKKMVLSSKFLNYIIKGASLLKQPHFNRLAAAQKQFKLQRYRILMTILTVVNILCLLCRLPNATSIQFTTYLGKFIGLTLFYAYSHVLALIRVVTSSVGIFLEQREMIAKLLLYGRTFGKLLLYSLGIGQQQ-VQQATFASCFIGIYPYAMLALCFLHTIYDGLKFTRFTIALLLWSGYAMGIEFLDPYISGIS-FILVGSFVTLVLLATNRTNLLSQVNRDESACESFHRLCADECDDETLSMLSQQLSGYSDISN-SNLSMRTASVCHSPAPTISQRTIQAPASLLSLDSLHLSKQRMEQQAWSSNYGDASTVVAPRVQPAMMFQQKPMRPLESQWYRHGQSNLAQGNTFTRSTQNLLMPSRLPSINRNVGGADVSAWVAANQSVNQDLCTANLMRHYEEKQQNQLSRTSSQSSGFESQPRPEAQCGTGAATVRDYGWSEARESQRNFAVFPPMPSPTPTITPSEYQYSRTALPQQQPTMQPGDLLRKWIEINSKSSQPIH----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* .. : ..*..:::: :. . ******* :. *** :**.* ** ******* ::****: *.:* *. .: . . * : ** :*.. * *:::*: * *::: .:*:*::**:.:**: ::** .*: *: ::.:: * : ::.: :: .:.. : : .. **: *:.: *: . .: . : ** . : * .:* : : :*: .: . : * :.:. * : : * : :*: . : . : .*.: * . : .* .. .. * . * : . . : . : . . .. ***.:: : . :*.. : : : :. . * * . ... : * . . :.. . *: * .: : :. . ... ... : : .: : .. . . : .. . . * * . : :: * * . . :: ", "identical_positions": 82, "similar_positions": 190, "identity": "11.83%" }, { "cls_id": "homologset.agr.MGI:1196281", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VHZ8-1", "uniprot_id": "DSCAM_RAT", "id": "Q8VHZ8-1", "name": "Cell adhesion molecule DSCAM", "aln": "--------------MWILALSLFQS----------FANVFSEEPHSSLYFVNASLQEVVFASTSGTLVPCPAAGIPPVTLRWYLATGEEIYDVPGIRHVHPNGTLQIFPFPPSSFSTLIHDNTYYCTAENPSGKIRSQDVHIKAVLREPYTVRVEDQKTMRGNVAVFKCIIPSSVEAYVTVVSWEKDTVSLVS------GSRFLITSTGALYIKDVQNEDGLYNYRCITRHRYTGETRQSNSARLFV-SDPAN--SAPSILDGFDHRKAMAGQRVELPCKALGHPEPDYRWLK-------DNMPLELSGRFQKTVTGLLIENSRPSDSGSYVCEVSNRYGTAKVIGRLYVKQPLKATISPRKVKSSVGSQVSLSCSVTGNE----DQELSWYRNGEILNPGKNVRITG-----LNHANLIMDHMVKSDGGAYQCFVRK---DKLSAQDYVQVVLEDGTPKIISAFSEKVVSPAEPVSLVCNVKGTPLPTVTWTLDDDPILKG---SGHRISQMITSEGNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVRGPASIRPMKNITAIAGRDTYIHCRVIGYPYYSIKWYKNANLLPFNH--RQVAFENNGTLKLSDVQKEVDEGEYTCNVLVQPQLSTSQSVHVTVKVPPFIQPFEFPR--FSIGQRVFIPCVVVSGDLPITITWQKDGRPIPASLG--VTIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVPPKFVVQPRDQDGIYGKAVILNCSAEGYPVPTIVWKFSKGAGVPQFQPIALNG--RIQVLSNGSLLIKHVVEEDSGYYLCKVSNDVGADVSKSMYLTVKIPAMITSYPNTTLATQGQRKEMSCTAHGEKPIIVRWEKE------DRIINPEMARYLVSTKEVGEEVISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQEPPDPPE-IEIKDVKARTITLRWTMGFDGNSPITGYDIECKNKSDSWDSAQRTKDVSP----------------------QLNSATIIDIHPSSTYSIRMYAKNRIGKSEPSNEITITADEAAPDGPPQEVHLEPTSSQSIRVTWKAPKKHLQNGIIRGYQIGYREYSTGGNFQFNIIS-------IDTTGDSEVYTLDNLNKFTQYGLVVQACNRAGTGPSSQEIITTTLEDVPSYPPENVQAIATSPESISISWSTLSKEALNGILQGFRVIYWANLIDGE--LGEIKNVTTTQPSLELDGLEKYTNYSIQVLAFTRAGDGVRSEQIFTRTKEDVPGPPAGVKAAAASASMVFVSWLPPLKLNGIIRKYTVFCSHPYPTVISEFEAS-----PDSFSYRIPNLSRNRQYSVWVVAVTSAGRGNSSEIITVEPLAKAPARILTFSGTVTTPWMKDIVLPCKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGSFVIRTVKAEDSGYYSCVANNNWGSDEIILNLQVQVPPDQPRLTVSKTTSSSITLSWLPGDNGGSSIRGYILQYSEDNSEQWGSFPISPSERSYRLENLKCGTWYKFTLTAQNGVGPGRISEIIEAKTLGKEPQFSKEQELFASINTTRVRLNLIGWNDGGCPITSFTLEYRPFGTTVWTTAQRTS-----LSKSYILYDLQEATWYELQMRVCNSAGCAEKQANFATLNYDGSTIPPLIKSVVQSEEGLTTNEGLKILVTISCILVGVLLLFVLLLVVRRRRREQRLKRLRDAKSLAEMLMSKNTRTSDTLSKQQQTLRMHIDIPRAQLLIEERDTMETIDDRSTVLLTDADFG-----------EAAKQKSLTVTHTVHYQSVSQATGPLVDVSDARPGT------NPTTRRNAKAGPTARNRYASQWTLNRPHPTISAHTLTTDWRLPTPRATGSVDKESDSYSVSPSQDTDRARSSMVSTESASSTYEELARAYEHAKMEEQLRHAKFTITECFISDTSSEQLTAGTNEYTDSLTSSTPSESGICRFTASPPKPQDGGRVVNMAVPKAHRP-GDLIHLPPYLRMDFLLNRGAPGTSRDLSLGQACLEPQKSRTLKRPTVLEPTPMEASSSTSS-------------------TREGQQSWQQGAVATLPQREGA-ELGQAAKMSSSQESLLDSRGHLKG-NNPYAKSYTLV----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ERC8-1", "uniprot_id": "DSCAM_MOUSE", "id": "Q9ERC8-1", "name": "Cell adhesion molecule DSCAM", "aln": "--------------MWILALSLFQS----------FANVFSEEPHSSLYFVNASLQEVVFASTSGTLVPCPAAGIPPVTLRWYLATGEEIYDVPGIRHVHPNGTLQIFPFPPSSFSTLIHDNTYYCTAENPSGKIRSQDVHIKAVLREPYTVRVEDQKTMRGNVAVFKCIIPSSVEAYVTVVSWEKDTVSLVS------GSRFLITSTGALYIKDVQNEDGLYNYRCITRHRYTGETRQSNSARLFV-SDPAN--SAPSILDGFDHRKAMAGQRVELPCKALGHPEPDYRWLK-------DNMPLELSGRFQKTVTGLLIENSRPSDSGSYVCEVSNRYGTAKVIGRLYVKQPLKATISPRKVKSSVGSQVSLSCSVTGNE----DQELSWYRNGEILNPGKNVRITG-----LNHANLIMDHMVKSDGGAYQCFVRK---DKLSAQDYVQVVLEDGTPKIISAFSEKVVSPAEPVSLVCNVKGTPLPTVTWTLDDDPILKG---SGHRISQMITSEGNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVRGPASIRPMKNITAIAGRDTYIHCRVIGYPYYSIKWYKNANLLPFNH--RQVAFENNGTLKLSDVQKEVDEGEYTCNVLVQPQLSTSQSVHVTVKVPPFIQPFEFPR--FSIGQRVFIPCVVVSGDLPITITWQKDGRPIPASLG--VTIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVPPKFVVQPRDQDGIYGKAVILNCSAEGYPVPTIVWKFSKGAGVPQFQPIALNG--RIQVLSNGSLLIKHVVEEDSGYYLCKVSNDVGADVSKSMYLTVKIPAMITSYPNTTLATQGQRKEMSCTAHGEKPIIVRWEKE------DRIINPEMARYLVSTKEVGEEVISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQEPPDPPE-IEIKDVKARTITLRWTMGFDGNSPITGYDIECKNKSDSWDSAQRTKDVSP----------------------QLNSATIIDIHPSSTYSIRMYAKNRIGKSEPSNEITITADEAAPDGPPQEVHLEPTSSQSIRVTWKAPKKHLQNGIIRGYQIGYREYSTGGNFQFNIIS-------IDTTGDSEVYTLDNLNKFTQYGLVVQACNRAGTGPSSQEIITTTLEDVPSYPPENVQAIATSPESISISWSTLSKEALNGILQGFRVIYWANLIDGE--LGEIKNVTTTQPSLELDGLEKYTNYSIQVLAFTRAGDGVRSEQIFTRTKEDVPGPPAGVKAAAASASMVFVSWLPPLKLNGIIRKYTVFCSHPYPTVISEFEAS-----PDSFSYRIPNLSRNRQYSVWVVAVTSAGRGNSSEIITVEPLAKAPARILTFSGTVTTPWMKDIVLPCKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGSFIIRTVKAEDSGYYSCVANNNWGSDEIILNLQVQVPPDQPRLTVSKTTSSSITLSWLPGDNGGSSIRGYILQYSEDNSEQWGSFPISPSERSYRLENLKCGTWYKFTLTAQNGVGPGRISEIIEAKTLGKEPQFSKEQELFASINTTRVRLNLIGWNDGGCPITSFTLEYRPFGTTVWTTAQRTS-----LSKSYILYDLQEATWYELQMRVCNSAGCAEKQANFATLNYDGSTIPPLIKSVVQSEEGLTTNEGLKILVTISCILVGVLLLFVLLLVVRRRRREQRLKRLRDAKSLAEMLMSKNTRTSDTLSKQQQTLRMHIDIPRAQLLIEERDTMETIDDRSTVLLTDADFG-----------EAAKQKSLTVTHTVHYQSVSQATGPLVDVSDARPGT------NPTTRRNAKAGPTARNRYASQWTLNRPHPTISAHTLTTDWRLPTPRATGSVDKESDSYSVSPSQDTDRARSSMVSTESASSTYEELARAYEHAKMEEQLRHAKFTITECFISDTSSEQLTAGTNEYTDSLTSSTPSESGICRFTASPPKPQDGGRVVNMAVPKAHRP-GDLIHLPPYLRMDFLLNRGAPGTSRDLSLGQACLEPQKSRTLKRPTVLEPTPMEASSSTSS-------------------TREGQQSWQQGAVATLPQREGA-ELGQAAKMSSSQESLLDSRGHLKG-NNPYAKSYTLV----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60469-1", "uniprot_id": "DSCAM_HUMAN", "id": "O60469-1", "name": "Cell adhesion molecule DSCAM", "aln": "--------------MWILALSLFQS----------FANVFSEDLHSSLYFVNASLQEVVFASTTGTLVPCPAAGIPPVTLRWYLATGEEIYDVPGIRHVHPNGTLQIFPFPPSSFSTLIHDNTYYCTAENPSGKIRSQDVHIKAVLREPYTVRVEDQKTMRGNVAVFKCIIPSSVEAYITVVSWEKDTVSLVS------GSRFLITSTGALYIKDVQNEDGLYNYRCITRHRYTGETRQSNSARLFV-SDPAN--SAPSILDGFDHRKAMAGQRVELPCKALGHPEPDYRWLK-------DNMPLELSGRFQKTVTGLLIENIRPSDSGSYVCEVSNRYGTAKVIGRLYVKQPLKATISPRKVKSSVGSQVSLSCSVTGTE----DQELSWYRNGEILNPGKNVRITG-----INHENLIMDHMVKSDGGAYQCFVRK---DKLSAQDYVQVVLEDGTPKIISAFSEKVVSPAEPVSLMCNVKGTPLPTITWTLDDDPILKG---GSHRISQMITSEGNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVRGPASIRPMKNITAIAGRDTYIHCRVIGYPYYSIKWYKNSNLLPFNH--RQVAFENNGTLKLSDVQKEVDEGEYTCNVLVQPQLSTSQSVHVTVKVPPFIQPFEFPR--FSIGQRVFIPCVVVSGDLPITITWQKDGRPIPGSLG--VTIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVPPKFVVQPRDQDGIYGKAVILNCSAEGYPVPTIVWKFSKGAGVPQFQPIALNG--RIQVLSNGSLLIKHVVEEDSGYYLCKVSNDVGADVSKSMYLTVKIPAMITSYPNTTLATQGQKKEMSCTAHGEKPIIVRWEKE------DRIINPEMARYLVSTKEVGEEVISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQEPPDPPE-IEIKDVKARTITLRWTMGFDGNSPITGYDIECKNKSDSWDSAQRTKDVSP----------------------QLNSATIIDIHPSSTYSIRMYAKNRIGKSEPSNELTITADEAAPDGPPQEVHLEPISSQSIRVTWKAPKKHLQNGIIRGYQIGYREYSTGGNFQFNIIS-------VDTSGDSEVYTLDNLNKFTQYGLVVQACNRAGTGPSSQEIITTTLEDVPSYPPENVQAIATSPESISISWSTLSKEALNGILQGFRVIYWANLMDGE--LGEIKNITTTQPSLELDGLEKYTNYSIQVLAFTRAGDGVRSEQIFTRTKEDVPGPPAGVKAAAASASMVFVSWLPPLKLNGIIRKYTVFCSHPYPTVISEFEAS-----PDSFSYRIPNLSRNRQYSVWVVAVTSAGRGNSSEIITVEPLAKAPARILTFSGTVTTPWMKDIVLPCKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGSFIIRTVKAEDSGYYSCIANNNWGSDEIILNLQVQVPPDQPRLTVSKTTSSSITLSWLPGDNGGSSIRGYILQYSEDNSEQWGSFPISPSERSYRLENLKCGTWYKFTLTAQNGVGPGRISEIIEAKTLGKEPQFSKEQELFASINTTRVRLNLIGWNDGGCPITSFTLEYRPFGTTVWTTAQRTS-----LSKSYILYDLQEATWYELQMRVCNSAGCAEKQANFATLNYDGSTIPPLIKSVVQNEEGLTTNEGLKMLVTISCILVGVLLLFVLLLVVRRRRREQRLKRLRDAKSLAEMLMSKNTRTSDTLSKQQQTLRMHIDIPRAQLLIEERDTMETIDDRSTVLLTDADFG-----------EAAKQKSLTVTHTVHYQSVSQATGPLVDVSDARPGT------NPTTRRNAKAGPTARNRYASQWTLNRPHPTISAHTLTTDWRLPTPRAAGSVDKESDSYSVSPSQDTDRARSSMVSTESASSTYEELARAYEHAKMEEQLRHAKFTITECFISDTSSEQLTAGTNEYTDSLTSSTPSESGICRFTASPPKPQDGGRVMNMAVPKAHRP-GDLIHLPPYLRMDFLLNRGGPGTSRDLSLGQACLEPQKSRTLKRPTVLEPIPMEAASSASS-------------------TREGQ-SWQPGAVATLPQREGA-ELGQAAKMSSSQESLLDSRGHLKG-NNPYAKSYTLV----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32U2G5-1", "uniprot_id": "A0AB32U2G5_DANRE", "id": "A0AB32U2G5-1", "name": "Cell adhesion molecule DSCAM", "aln": "------------MERYFLFFLFYLTWSGFRLKRNVFVSVLSEDLHSSLYFVNASLQEVVFASTTGTLVPCPAAAVPPATLRWYLATGEESYNVPGIRHVHPNGTLQIFHFPPSSFSKVIHDNTYYCTAENPSGKIRSQDVHIKAVLREPYTVRVADQTAMRGSVAVFKCIIPSSVENYITVVSWERDTVPLVS------GARFLITSTGALYILDVQKEDELFNYRCMTRHRYTSETRQSNSARLFVPADPSN--SAPAILDGFEKREVMASHRVELPCKASGHPAPKYRWLK-------NNRPLESDSRFRQSVTGLLIERAQPSDTGSYVCEVWNSYGNAEVIGRLTVKEPLKAVVSPRKVKGSVGSQVSLSCSVTGSD----EFELSWYRNGDKINTGANIRMNG-----INKENLVMDGMAKSDGGVYQCFSRK---AKMSAQDFVQVILEDGTPKILSAFSEKVVGPNDFVSLTCHVKGTPQPAITWTLDDEVVAKD---SRHRIVHSITAEGNVVSYLNISHIQVRDSGVYRCTCNNSAGTVSYQARINVRGSADIRPMKNLTAIAGWDMYIHCHVIGYPYYSIKWFKNSNLLPFND--RQRAFENNGTLKLLNVQKELDEGEYSCHVQVQPQLFKNQSVHVTVKVPPFIQPFEFPR--YSIGHRVFVPCVVRSGDLPISITWEKDGKSINASLG--VTIDNIDFTSSLRISNLQRVHNGTYTCIAQNDAAVVKYQSQLIVRVPPRFKVQPQDQDGIYGKSVILNCSADGEPRPTIEWKYSKGAGVPQFQPIALNSGFRVQLLGNGSLLIKHVLEEDAGYYLCKVSNDVGADVSKSMYLNVKIPAMITSYPNNSLATKGEKIEMSCKAHGEKPIMVRWEKEVEKEKQSHMINPDMWRHTVTVKNVGDEVVSTLQIYPTMREDSGFFSCHAINSYGEDRGILQLTVQEPPEPPK-VEIREVKERTIALRWTMGFDGNSLITGYDIECKNKTETWERARRTRDVSP----------------------TLNQATIIELHPSSTYNIRMFAKNHIGDSEPSNELTVTTDEADPEGPPQDVTLEAITSQSIKVTWKAPLKHLQNGVIRGYQVCHREHSTNGSHQFVCIS-------VEATGETESLSLNNLKKFAEYEVVVQASNSAGPGPASSEVRATTMEDVPSRAPEKVVATAASPESISLSWQTPAREALNGVLQGFRIIYWANLPDGE--LGEIRNVTTHKAPLELEGLEKYTNYSIQVLAFTRAGDGVRSDQIYIRTKEDVPGPPGGVKAAAASSSVVYVSWLPPLKLNGVIRKYTVFCSSTSPTVVSEFEVA-----PDEFLHRVHNLSRNRKYNIWVMAVTAAGRGNSSDVITVEPLAKAPAKILTFSGTVTTPWMRDVVLPCRAVGDPPPAIKWLK-ESGSPAPAVIDGRRSIHGNGSFIIKTVKAEDSGYYTCVASNNYGTDEIILNLQVQVPPDQPRLTVTKTTTTSITVTWTPGDNGGSSIRGYILQYSEDNSEKWGSISISPSERSYRLENLNCGTWYKFTLTAQNAVGPGRISEIIEAKTHGKEPQFSKEQELFTSINGTSVKLNLIGWNDGGCPITSFTLEYRPLESPVWTKAKRTS-----LSKSYNLLDLQEATWYELQMKVYNSAGLAEKRVKFATLSYDGSTIPPLVKTLVKDPVKKTSNEGMKMMVTISCILVGMVLLFVLLMVLRRRRREQRLKRLRDAKSLAEMLMSKNTRPSDTMNKQQQTLRMHIDIPRAQLLIEERDTMETVDDRSTVLLTDNDFG-----------ETAKQKSATVTHSVHYQSLSQATGPLVDVSDVRPGTSKSSLSNPTSRRTAKAGPAARNRYASQWTLNRPHPPVSVHTLSTDWRLGTPRVAGSVDKESDSYSVSPSQDTDRARSSMVSTESASSTYEELARAYEHAKMEEQLRHAKFTITECFISDTSSEQMTAGTNDYTDSLTSSTPSESGICRFTASPPKPQDVCRVINMAVPKAHRPGGELVHLPPYLRMDFLLNRGVSGTSREAAMGQACLEPQKTRSLKRPALLEPTPMEVPTS------------------------RDVQQWQSGTASTLPQREAGTDLAQAAKISTSQESLLDSRGHLKQTNNPYAKSYTLV----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1Q4W9-1", "uniprot_id": "F1Q4W9_DANRE", "id": "F1Q4W9-1", "name": "Cell adhesion molecule DSCAM", "aln": "--------------MWILAFLFLQS----------ILNVFGEDLRSSLYFVNASLQEVVFSSTTGALVPCPAAAVPPATLRWYLATGEEIYDVPGIRHVHPNGTLQIYGFLPSSFSNLINDNTYYCTAENPSGKIRSQDLHIKAVFREPYTVRVADQRVMRGNTAVFKCIIPASVEEYVSVVSWEKDTVSLVS------GSRYLITSTGALYILDVQSEDAVNIYRCTTRHRYTGETRQSNSARLLL-SEPVD--SAPVILDGFERKEVMVGHRVELPCKASGHPPPRYRWLR-------DNSPLESDSRYHQSVSGLLIEATRPSDAGSYVCEVWNSFGNAKVVGRLVVKQPLKAVVSPRKVRGSVGSQVSLFCSVTGSD----EFDITWYRNAEKIYQGINVRITG-----INNENLVMEGMAKSDGGAYQCFARN---GKMSTQDLVQVVLEDGTPKILSAFSEKVVSPNEPISLVCHVKGTPLPTVTWTLDDDPVIKD---SNHRMDRIITTEGHVLSYLNVSHTQVSDGGVYRCTCNNSAGSVSYQARINVRGPASIRPMKNVTAIAGRDTYIHCRIIGYPYYSIKWYKDSNLLPFNH--RQRAFENNGTLKLSNVQNS-DEGEYTCYVLVDPEKQIHRSVHVTVKVPPLIQHSDSQS--ASIGQRVFIPCVVISGDLPMSITWHKDGRPINASLG--VTIDNIDFTSSLRISNLSEIHNGSYTCIARNEAAAVEHSIQLIVKVPPHFEVQPKDQDGIYGKSVTLNCSAKGNPIPTIVWNHSKGAGVPQFQPIALNSGSRVQLLENGSLLIKHVLEEDAGFYLCKVSNDVGADISKSMYLTVKIPAMITSYPNTTRAEQGHMTEMSCTAHGEKPIKVRWEKE------SHIINPDMSRYVVTVKEVGDEVISTLQILHTVREDSGFFSCIAINSYGEDKGIIQLIVQDRPDPPE-VEIREVKDRTIALRWTMGFDGNSPITGYDINYKNKSASWASSQMTKDVSP----------------------QLNQATIIELHPASTYNIRMFAKNQIGESRPSNELTITTDEAPPDGAPQDVQLEAISSQGIKVTWKPPHKHLQNGLIRSYQVCYREFGTGGSPQYNTIN-------VDTTGDIETLTLDNLKKYTQYEVRVQAANRAGMGPTSEEITITTLEDVPSRPPENVVTTATTPETISLSWSALPKEALNGMLLGYRVIFWANLPDGE--LGEIRNITTTKPSLELERLEKYTNYSIQVLAFTRAGDGVRSEQIYTRTKEDVPGPPAGVKAAASTSSVVFVSWLPPHKLNGIIRKYIVFCSNPYPTVISEFEAA-----PDVYFRRLTNLNQNWQYSIWVVAVTAAGRGNTSEIITVEPQAKAPARILTFSGTVTTPWMRDIVLPCKAVGDPPPTIKWLKGNNGTPAPVSIDGRRSAHNNGSFVIRTVKAEDSGYYRCVASNNWGSDEIMLNLQVQVPPDQPRLTVTKTTTTSITLFWIPGDNGGSSIRGYILQYSEDNSEEWGSYSISPSERSYRLENLKCGTWYKFTLTAQNAVGPGRISEIIEAKTHGKEPQFAKDHELFSSINSTRVELNLIGWNNGGCPIDSFTLEYRPVDTTKWTMVKRDS-----LTKSHILYDLQEATWYELQMRVGNSAGTAEKRVLFATLNMDGSTIAPLPKSVDPSQENRQGNEGLKMMVTIICILVAICMVFIVLLVLRRRRREQRLKRLRDAKSLAEMLMSKNARTPDTVNKQQQTLRMHIDIPRAQLLIEERDTMETIDDRSTVLLTDNDFG-----------ETSKQKSSTVTHTVHYQSLSQATGPLVDVSDARPGT------NPTARRTAKAGPATRSRYASQWTLNRPHPPVSSHTLTTDWRLPTPRATGSVDKESDSYSVSPSQDTDRARSSMVSTESASSTYEELARAYEHAKMEEQLRHAKFTITECFISDTSSEQMTAGTNDYTDSLTSSTPSESGICRFTASPPKPQDASRVMNMAVPKAHRPAGELVHLPPYLRMDFLLNRGAASSGRE-ATGQTCMDPQKSRITKRPALLAPTPSETPSSALSSS--------------GPPSREAVQQWQPGTASTLPQREPG-DLAQAAKLSSSQESLLDSRGHLKQSNNPYAKSYTLV----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q0E9H9-1", "uniprot_id": "DSCA1_DROME", "id": "Q0E9H9-1", "name": "Cell adhesion molecule Dscam1", "aln": "MNMPNERLKWLMLFAAVALIACGSQT--------LAANPPDAD-QKGPVFLKEPTNRIDFSNSTGAEIECKASGNPMPEIIWIRSDGTAVGDVPGLRQISSDGKLVFPPFRAEDYRQEVHAQVYACLARNQFGSIISRDVHVRAVVAQYYEADVNKEHVIRGNSAVIKCLIPSFVADFVEVVSWHTDEEENYFPGAEYDGKYLVLPS-GELHIREVGPEDGYKSYQCRTKHRLTGETRLSATKGRLVITEPVSSSPPKINALTYKPNIVESMASTAILCPAQGYPAPSFRWYKFIEGTTRKQAVVLNDRVKQVSG-TLIIKDAVVEDSGKYLCVVNNSVGGESVETVLTVTAPLSAKIDPPTQTVDFGRPAVFTCQYTGNP----IKTVSWMKDGKAIG--------------HSEPVLRIESVKKEDKGMYQCFVRN-DQESAEASAELKLGGRFDPPVIRQAFQEETMEPGPSVFLKCVAGGNPTPEISWELDGKKIANN---DRYQVGQYVTVNGDVVSYLNITSVHANDGGLYKCIAKSKVGVAEHSAKLNVYGLPYIRQMEKKAIVAGETLIVTCPVAGYPIDSIVWERDNRALPIN---RKQKVFPNGTLIIENVERNSDQATYTCVAKNQEGYSARGSLEVQVMVPPQVLPFSFGESAADVGDIASANCVVPKGDLPLEIRWSLNSAPIVNGENGFTLVRLNKRTSLLNIDSLNAFHRGVYKCIATNPAGTSEYVAELQVNVPPRWILEPTDKAFAQGSDAKVECKADGFPKPQVTWKKAVGDTPGEYKDLKKSD--NIR-VEEGTLHVDNIQKTNEGYYLCEAINGIGSGLSAVIMISVQAPPEFTEKLRNQTARRGEPAVLQCEAKGEKPIGILWNMNN-----MRLDPKNDNRYTIREEILSTGVMSSLSIKRTERSDSALFTCVATNAFGSDDASINMIVQEVPEMPYALKVLDKSGRSVQLSWAQPYDGNSPLDRYIIEFKRSRASWSEIDRVIVPG-----------------------HTTEAQVQKLSPATTYNIRIVAENAIGTSQSSEAVTIITAEEAPSGKPQNIKVEPVNQTTMRVTWKPPPRTEWNGEILGYYVGYKLSNTNSSYVFETIN---FITEEGKEHN---LELQNLRVYTQYSVVIQAFNKIGAGPLSEEEKQFTAEGTPSQPPSDTACTTLTSQTIRVGWVSPPLESANGVIKTYKVVYAPSDEWYD--ETKRHYKKTASSDTVLHGLKKYTNYTMQVLATTAGGDGVRSVPIHCQTEPDVPEAPTDVKALVMGNAAILVSWRPPAQPNGIITQYTVYS--KAEGAETETKTQKVPH--YQMSFEATELEKNKPYEFWVTASTTIGEGQQSKSIVAMPSDQVPAKIASFDDTFTATFKEDAKMPCLAVGAPQPEITWKIKGVEF----SANDRMRVLPDGSLLIKSVNRQDAGDYSCHAENSIAKDSITHKLIVLAPPQSPHVTLSATTTDALTVKLKPHEGDTAPLHGYTLHYKPEFGE-WETSEVSVDSQKHNIEGLLCGSRYQVYATGFNNIGAGEASDILNTRTKGQKPKLPEKPRFIEVS-SNSVSLHFKAWKDGGCPMSHFVVESKKRDQ---IEWNQISNNVKP-DNNYVVLDLEPATWYNLRITAHNSAGFTVAEYDFATLTVTGGTIAPSRDLPELS--AEDTIRIILSNLNLVVPVVAALLVIIIAIIVICILRSKGNHHKDDVVYNQTMGPGATLDKRRPDLRDELGYIAPPNRKLPPVPGSNYNTCDRIKRGRGGLRSNHS-------------------------TWDPRRNPNLYEELKAPPVPMHGNHYGHAHGNAECHYRHPGMEDEICPYATFHLLGFREEMDPTKAMNFQTFPHQNGHAGPVPGHAGTMLPPGHPGHVHSRSGSQSMPRANRYQRKNSQGGQSSIYTPAPEYDDPANCAEEDQYRRYTRVNSQGGSLYSGPGPEYDDPANCAPEEDQYGSQYGGPYGQPYDHYGSRGSMGRRSIGSAR--NPGNGSPEPPPPPPRNHDMSNSSFNDSKESNEISEAECDRDHGPRGNYG-------------------------------AVKRSPQPKDQRTTEEMRKLIERNETGPKQLQLQQANGAGFTAYDTMAV--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "M9PHS6-1", "uniprot_id": "M9PHS6_DROME", "id": "M9PHS6-1", "name": "", "aln": "MDLHS-------LFKAILILYVIRAE--------TSQFVNGLD-LQGPIFLHEPPHRVEFSNNSGGLIECSGHGSPPPEVEWTP-----IPPQQDMVFQLSNGSMMFYPFTAEKYRHEVHATVYRCKLRNLVGTVLSREVHVRGVVNQKYAVQVHDEYVMTGNTAVLKCQVPSYMSEFVLVTAWVQDTGMHLYPNTDIGGKYTVLSN-GELYINNAGPNDAYKSYTCRTVNRLTGEVQISTYPGRIIVTEPKGMVQPRINVEKHSMRHVVLNGQTTLPCIAQGHPVPTYRWFK--EENEQLLPLQLSERITIVSAGLLKITKARLEDSGKYLCWVNNTAGEETIQVSLTVTAPLTAHLQPQVQTVDVDKDAQFQCIVSGHP----VHDVNWLHDGKPILRDNRVEI------LTDPPRLIIKKVQKEDPGMYQCFVSN-EWEQIQSTAELQLG--DASPELLYWFSEQTLQPGPTVSLKCVATGNPLPQFTWSLDGFPIPDS---SRFLVGQYVTIHDDVISHVNISNVKEEDGGEYTCTAQNAIGKVSHSAKVNIYGLPYIREMPKITGISGSDLIVKCPVAGYPIDKIHWERDGQTLPIN---RRQRAYNNGTLIIEQLQRLEDAGTYTCMAQNKQKQTSRRNVEIQVLVPPKIMPIQAMTNMLREGMRAAISCQILEGDLPVSFRWERNGKPLIGTGN-EVFRRLDEYSASLVIEHISSDHSGNYTCIASNVAGTERFTVPLTVNVPPKWILEPKDSSAQAGADVLLHCQSSGYPTPTITWKKAIGPTPGEYKDFLYEP--TVQLFPNGTIFFKKISKESQGHFLCEAKNNIGSGVSKVIFLKVNVPAHFQTKTKQISVAKGKQVHVQCNVQGDNPIDFKWKIQAT---QQYLDESLDSRYTIRDQVLDDGMVSELGISHTYRQDTGIYICQASNAFGQDEMSIQLIVQEVPEQPKNLRINSQQSRSLQLTWSQPFAGNSPIEEYHIYYKQISDIWQNAEHLTIAG-----------------------AQTVINIQQLRPAKAYHIRMSAENKLGASEFSEVVQVTTLEEVPSGPPLAVRAEPKSSTEIFVTWDAPERDHWNGILLGYYVGYQMSLTPEDKEVNPTQGFSFKTVEVRSHFGGETVLANLNKFTQYHVIVQAYTSQGSGPPSKEIAVQTMEDVPSSPPESPQCDVLGSTSIYITWSPPDIDGQNGKIKGYKVFYISVDELY---ETDPEVVKSTNQYVTIENLRKYTNYTVWVLAYTKVGDGMKTKPFYCRTHEDVPSAPQAIKAIPASSSKIIISWLPPDLPNGDITGYTFYMSMLEGGREEGTHKRLLGP--FVEMHETVRTQESATYQFWLTASTKMGEGEKTQVVTVPPNNKVPARIVSFSQRIVTPWKEHLELPCRKVGAPAPVTIWRQDGHNM----ETSARKTIAKNGTLYMKECQASDAGNYTCSVENTWGKDEIVYNIVVKVPPEAPNLTVINAYTDSLLLEWMDNSHGGSPILGYVINYKRDNGD-WEELQVDSKTTSHLLTNLWCGTRYQLYITAYNKIGTGLPCDIVNSYTKGNPPVQPKHSQMITNN-STSVTCWLDSWGDGGCGILYFMIESRVYGR---SSWAVVSNHIPPTERIYTVSDLVPGTKYQLKVTAHNNAGSTTAIYNFTTLSTQGVIYNNDHSTPVSH--LSDLP--FYANFKLLLPICFSLLMLLALIGAALFLR-KRKLASQARLASSSMSESPSLANLQNKQNRDQQYLA--------------------------VRCNPG-------------------------TSAPRGSN-----------SNDSGSFGKAEGN--------EYIEDICPYATFQLN---------KQTYSESSYSGNVYSGPYHSVRGSFVYH----DVKPESYHSKEPEYTKVRRK--VGRLRDPHSESQESDNPG--STDSEVRKILTLHIPITEYDTLGSESDNDVSARALNSAKYRAQRDTQDETSSSSETTPTSMTRKSKPPFA--ARKGGKPGTSG---KRHVRSSSGYSSHNEETTFSISNYPPNY--QDHIN-------------------------------PPARFSDANDKTKTQTSPRMRANQKLHREAFQINV----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VS29-1", "uniprot_id": "DSCL_DROME", "id": "Q9VS29-1", "name": "Cell adhesion molecule Dscam2", "aln": "MWISSR--------FFVILLLLNLDN--------TCSEPFEAH-LRGPGFVMEPPGRVEFSNSSGGWLDCSASGSPQPTVDWVHADGSAVTEIHGVRRVLRNGTLVLMPFAAAAYHQDVHNTIYRCIASNSVGRIVSRDVQVRAVVAQAYKVDVEVLSAARGCTAILRCVVPTFVKELVRVVSWVHEPAIYIYPSLQGDGKFHLLPT-GELLIHNLQESDESQSFRCRSMHRLTRQVVVSSPT-RLRINSHRGIISPSVVEHTAHVQVSQDEG-AVLLCVAQGCPSPEYSWFT--HNGAGPLPVLSGPRVRLLGP-ILAIEAVTGEDSGVYKCTAGNVGGEASAELRLTVATPIQVEISPNVLSVHMGGTAEFRCLVTSNGSPVGMQNILWYKDGRQLPSSG-----------RVEDTLVVPRVSRENRGMYQCVVRRPEGDTFQATAELQLG--DAPPVLLYSFIEQTLQPGPAVSLKCSAAGNPTPQISWTLDGFPLPSN---GRFMIGQYITVHGDVISHVNISHVMVEDGGEYACIAENRAGRVQHAARLNIYGLPYIRLIPKVTAVSGETLNLKCPVAGYPIEEIHWERGGRELPDD---IRQRVQPDGSLTISPVQKNSDSGVYTCWARNKQGHSARRSGEVTVIVPPSIEPFAFQEGLAEG-MRTRTVCGVSRGDPPLKLIWLKDGDPLPDLLG-ANVTMLDQYSSLLSIPSLSATHSGEYTCVAKNPAAEIKYTALLQVKVPPRWIVEPVDANVERNRHIMLHCQAQGVPTPSIVWKKATGSKSGEYEEVRERP--FTKLLGNGSLLLQHVKEDREGFYLCQANNGIGTGIGKVIQLKVNSSPYFSSTSRSVMVKKGDTALLQCAVSGDKPINIVWMRSG----KNTLNPSTNYKISVKQEATPDGVSAELQIRTVDATDSGPYFCRASNLYGNDQQLVQLQVQEPPLPPSVLEAAMISSRSVNIKWQPKTLGTGDVTKYIVEFREADPLFVDQWQQIEVKDP---------------------PHFNAMIENLKPATRYAFRVIAEGSAGRSAPSQELIVRTEPQRPAGPPLSLSARPLSSTELLISWVAPLPELRHGDIQGYNVGYKLSSSGNTAYNFTSVS------GDGDGGNGELLLSGLAKFARYTVVVQAFNQVGPGPLSEPTAAQTMEDVPSRPPEDVRCAALSSQSLQVSWQPPPIYHTNGLLQGYKLIFEPIIDDIQPSKDEVESRKTTALTMVLTGLRKYTNYSIQVLAHTRMGDGVVSKPLFCHSEEDVPEAPADIKVVSSSSQSLYISWLPPNEPNGVITKYSLYTRVVNGREELNNEKRSLPS--QQAYYEAKGLHPHMEYQFWVTASTRVGEGKSSRVSSQITTNRIPARIISFGGPVVRPWRSTVTLPCTAVGKPKREWFKSDVALRQ----GGLHNSQLLDSGDLIISSLQLADGGNYSCQVDNGIGTDRLTHTLIVQVPPTAPVLYVTSATSSSILMHWKCGFTGNAPITGYTLFYRRANGN-TDEMQLSRHASSHELKGLMCGSTYQIHLSAQNKVGTSPTSTILHVRTQGQSPGHPASTALLAPN-STSLLVRLHSWPDNGCPLLYFVLQYRAVTDDPDAEWVLVSNALKP-QRRIVINNLQPSTLYQLRMEAHNVAGISQAEFNFVTLTKDGDPPPP--EIMHRG--RSGQTTVIFANINLLIPTIAAVSGMFCTIIMIIVCYRHMLKNAPPLAEQSQIQKESLENRANSEAAQRERYYATIHKVSMQNNDKIPETSEDISPYATFQLSEAGGNMSQPHHGGPANTLLHSFMYHERALAEGCSSPPPAAVLNPPTTTTHHHHHHQRPLKTIHNYYQTSPFHNISKNRRRHSRKTEPESEESESDQDQLTSSRTESSNQHEGKIKHSIIYHG-AQSSTSSDLSPMSEQKSLPRRGRSRYHHQQYQFSTNTTPRHHNSNKMNNNTTSNTNTTATNTTATPSTSSNSNKILSPRGGNLKSISSTFKSQDSIQCHIPTLVKSPSISTQQ--QKQFHKQQLQNSSTNNSQHSSSNPNSSSLKQQQPLLITPKLHQLEANGQELLGLDGIGNSPLVACMPPSSQFRPIPHKSIMPAHEPPHHHNHSQQSHPHQQQQQQQHPGTLLNPSTAMLSSKFFTAPTLPK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q7KSE9-1", "uniprot_id": "Q7KSE9_DROME", "id": "Q7KSE9-1", "name": "", "aln": "--MSLLEPPCLVLEKALLLGALLLAV--------LATPLLATSGLRVPTFLLEPAPRLLFGNDTGAQVTCTAHGSPPPLVTWVLRDGSLATQVPGLRKISGNGTLHFPPFLAQYYRTDVHEATYRCRASNEAGTVLSRNVQVHAVVRRQFHVHVENTEVYLGNSALIKCAIPEYVRPYVRVASWHRGEEILLPDLSDVAGRYVVLAASGDLYVRSVRSEDGLMKFSCLVTNTLNGERQR-SDAVMLQVKELSKNLAPRTTQKPVMEIHVERGNDVHLPCNIQGNPFPIFTWYR--VSDSAALYPIPSSQRVILSRTLLLIKNADERDAGKWICQASNQFGEQRIEIRLSVNSYVSVHILPQVQIVNSGGTANFNCTTTGSA----IDAIDWLHNGKPLQANNALTTGRDNIRFLSKSSLLVQNVGRRDRGVYQCLVEN-QRASAQAMAELKLG--DTVPELIYTFIEQNVRPGPLISLKCSASGSPPPQFAWLLDSQPIMDVSLHHRFAIGQFVDMSGDVISHLNISHVRPDDGGLYKCVASNSMGSVQHSARLNVYGPPYVRAIGPIKAVAGEDIIVHCPFAGYPVEQIRWEKAHQELTTSNHYELASVADGGQLVIKNVEPGRDQGIYTCIVRSRAGEEARRDMQLNVNSPPVIEPFKFPKNLQEG-GRAQITCAVSSGDMPIYFSWKKDDSSIPSSLQ--ITEKKEEFYSLLVFKDISARHSGKYTCYASNAAAKVNYTAELQVRVAPRWRYEPMDTAIMLGNTISINCEAEGYPIPTITWFKGQGKGSKDFKPLSMR---------NHSLLLNLATDNDEGYYMCQATNEIGAGLKKTIRINVNEPARFEQSARNISSRRNDPVTLDCHAKGDEPITIGWTQNNG---RIDLN---NFRFSIAEMKTEKGVDSQLTIGHSDRHDSGVYRCIAENPYGRAEQIIFLAVQERPDTPSHLEIFEVGSRTVKLSWRRPFDGNSPVLSYLVQYQALKYLQSHGSLAAAGGDWNGHVINVSLPSTSISRSYDSDLRESAIVAGLTPATTFLIRMQAINEIERSAYTEAIVLKTQEEAPTEAPSNVQVQTGGESELIVTWQIPPRESWNGELIGYTVNCSEEKQNINFISVVNSS--LKSTIVSGWATTKATLRGLRKYSRYAVTIRAMNSFGSGPWSAAIFGTTAEGVPEAAPQNVNCTALSSQSLKISWLEPPLQFHGGIIQGYKILYRPIVHQID-FPAKLEIKRTSNLETYLHTLHKASNYSIRVLAYTATGDGLASHPLFCQTDDDVPDAPAAIKAAALTADSILISWLTPKNRNGIISHYTVYSREAGRKGQAKTHMVRVDENGYPVTFESRSLAENQMYEFWVSASTSVGEGEPTSVIAQATNTRAPARIASFGQVVRKAVGTGLVLECLAVGNPTPRARWLTRDRPV----TFSPFYEVTNEGNLKIHRVEGSLSGNYTCTANNLFGSDEIQYQVIAMKPPSAPQIIVQYASADSIRVSWDAPDDGGAPLQGYTISYHTAGES-WSITELLPENNAFTISGLKCGNQYIIKMSAHNMVGSGVASEEINVWTKGKASQAPNANELIATN-ATCVNLKLSSWQNGGCSIHHFSIEHRPLGDIRWTVVTSDISNAEENRENLIFCDFLPAKWYQLRISATNDAGKTTEHYHFSTTNIDGITIPPPSVFPSENDLMNNLINSTNPTSGDWFATLIVVVIITVSIITIALTIKHRRTLCGPIAEGYESRTLPGDYKEDHENRRNQQVYSASPVKTVDKGNESEMYEISPYATFSVNGGRTG-----APAKTPTRAVAAQTPLDYTMQFKTFGHPEGENLNATAYPLLPSSGFGHVKSKSSWHKQRYYNTEDESTLSKSMTIVAGSQAGHSKKSNGGRSAKSSAACSGVVAGSESDTSISPSTEFSNMPTYRVPCKSSRSSDGRAVVDMFRPDSSTESNNDQGSPAPERRHNTPRHVLGMGMAMGLGGGGGGGVGGGNGPAEKRSAGQRSRKHGSAAQQPSNQTLERRKCPGSSNSLDSEVDAETAASLAASIAAMAGSGAGADLSGGFRPPAGFHDGREPGDHSDCE-------------------------REQRALDLEVQRVMESTGDAQLAKMDREELTSLLARYHEKKEQERLEYTIHV---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *: . .: *.. :* : * . . * : * .: :*.: : * . : :: * * * * : *::::::.*. . : . * . * *:::* :* : : *.:* * ::. * * : . .* : * : . : : . . . : * * * * : * * * *:* : * . * * * * : . : * . . : * :. : * ::. : * : : : : * ***. . .: ::: * : * *: : * : * * . *.* * .:* **. : . . : : : ..*:*::*:: *.* * * ... * . : *::*: * . :* : ::* : * . *** .* * : . *. . .* * : :: * . *:* . . .: * ** : . * : ** *: : * :. .: . : * : :. * * *.* * * *. .. * *.*.*:: :* * . :.*.:.* * * : * . * ::: . : :: .. . *.::*:. * :*:.: : :.*: .. : . :.. :.* . *::** . * . : : : : : * * *:. : * * * :* : : **: * * :. *:: : * *.. : * : : : : *:. : :*: * . * :: : : : * * : .. . : ::* * :* : .* : * .* ::.* : ::* . * ** * * *..*. .*.. . . :: : * .* : :::.: . . . : : *.* :**:: *** * ***: : :. ::. *** .* :*. : :** .* ** * * .: . . *..*: * * *.*: : . : **:* :*. . . : * ** * .* : : : .* * * ..* ..* : : . ** * : : : : :: : . :.: ** : * . : . : .* **. * . :. * :*.. . :. * *: . . :: . : : .* :.** : * :: : . . :: .. *:*:: . * ** : * * . * : : : . . . . . . . . . : . : .:. ", "identical_positions": 231, "similar_positions": 403, "identity": "10.66%" }, { "cls_id": "homologset.agr.MGI:1196284", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99576-1", "uniprot_id": "T22D3_HUMAN", "id": "Q99576-1", "name": "TSC22 domain family protein 3", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNTEMY---------------------------------------------------------------------------------QTPMEVAVYQLHN---------FSIS----------FFSS----------LLGGDVVSVKLDN----------------------------------------------------SASGASVVAIDNKIEQAMDLVKNHLMYAVREEVEILKEQIRELVEKNSQLERENTLLKTLASPEQLEKFQSCLSPEEP----------------APES---PQVPEAPGGSAV------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9EQZ1-1", "uniprot_id": "T22D3_RAT", "id": "Q9EQZ1-1", "name": "TSC22 domain family protein 3", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNTEMY---------------------------------------------------------------------------------QTPMEVAVYQLHN---------FSIS----------FFSS----------LLGGDVVSVKLDN----------------------------------------------------SASGASVVALDNKIEQAMDLVKNHLMYAVREEVEVLKEQIRELVEKNSQLERENTLLKTLASPEQLEKFQSRLSPEEP----------------APEA---PETPEAPGGSAV------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z2S7-1", "uniprot_id": "T22D3_MOUSE", "id": "Q9Z2S7-1", "name": "TSC22 domain family protein 3", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNTEMY---------------------------------------------------------------------------------QTPMEVAVYQLHN---------FSIS----------FFSS----------LLGGDVVSVKLDN----------------------------------------------------SASGASVVALDNKIEQAMDLVKNHLMYAVREEVEVLKEQIRELLEKNSQLERENTLLKTLASPEQLEKFQSRLSPEEP----------------APEAPETPETPEAPGGSAV------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q24523-4", "uniprot_id": "BUN2_DROME", "id": "Q24523-4", "name": "Protein bunched, class 2/F/G isoform", "aln": "MFDRTVNAKFKPASSNAGPGNNPVRRNSMLTPSRGVTIGGTGGNIRKLTKVSSLTSNHHFAVCYPPSNIYQNSNNAGSNSALQRTTSESLRLNMMSRVAAGATPTTVSRASSNSSLATSTSTSLAPKSSSSSGGSNSTPQQQQQQLVSSNNSSSSSNNSFTKASSPNNNGARSVGGAATSAATGTTAAAGSHHHQPHHHHHHHHHHHQHHNHQQQQQQQTSLSQGHASLTVAGGSASAGGGGGGGSGSSSGTAAGGTNRKPKTTSSFEITSVTVGHPKLNAAGDTGDESADDLDESHTDDNSRITDLENETPSMSEDTFSKEEVYYANNALSTNAPVIPTSSQYGLVVVDPIAPSLGQTIQNVQVNVSDNIINVVSGAVTPGGTKKKDDIKETQHRSERFKVVKIESTEPFKRGRWMCMDYLDHSSVGNGGNNNEKTGSSTSEAHAATTDGGAAGVGAGSEAPAHKTTQSMILPPTQKLNENHLEANSTDANWNYAEQQQQQQQQQQQQQTIVGNALTKTLPVALRNVSRSSSVTRSPNATVEFLSPNLLAQQQQQQQQLFDSVNANAASSPNPAGDPNNMDYARTAAMQLHQTLQQLKQREDAMDVPPGAGGYANYQNGGDSAVGAASNNNSAAAATGESQLSTSYVEQQQQQQQPLSPAPLTPQAAPTFAAVAAGQSPNFQLEQQQQQQQATSQIDGIVPQPFNPQQQQQQTPQQSTAQQAAAAANATSAVTAPPPQQTSNTSNAAVTTGQGQTMPLLSHMTSYEQQQPNLGAAAAAAAAGGTAATSVAAPQAIPTLQLQSAPSTIADPQQLMVPQQQQQQQHQEEQQQQPQQQQQPLPPANIASASANNSNLNLTNTNVVATGEATTNALTLTDEQATAALAAAFATGAAAAATGATSAAAATQQQIQQLQQQPNAESETESFITASNPGGNRKRAFSNPHIGGPNDPSFMHRLNPQLYYYNKSQSGRSSFCVDESLWPTNNPNGAVSDTNLYMGSSTDEDYEEAIDQFSPTIYTTRSASRAIPIPNSAGSSPQHQMHHSQPRIAIGINQMEGGGPTRSTGAFSASPSIYAYPHSPFYASSPETSFGSAAMPGHPAASSRISFSYDPAFQRLQVPNASGDRRPRSPLECASVFAAVAAAATCGDAAGGAADTVISSASGTSAVAIDNKIEQAMDLVKSHLMIAVREEVEVLKERISELMDKINKLELENSILKSNIPQETLQQLQLQLQLAAPPATPAIQAAPAVQSVVAPAAAGQAVQQQAAGAVAVTGVATSPASAVVPTSIPNGSAENGSSAVESAAVSVEQQVQQVTSAAAAAASVVTANGPMS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*.::* *. : :.: *:.. ** * *::* : * ..* ::. ****:*.**:************.*** *******:***:* **::* .:** **::**: . * *:::* *. * ** : . :*.*. ** ", "identical_positions": 64, "similar_positions": 43, "identity": "4.81%" }, { "cls_id": "homologset.agr.MGI:1196287", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O54788-1", "uniprot_id": "DFFB_MOUSE", "id": "O54788-1", "name": "DNA fragmentation factor subunit beta", "aln": "MCAVLRQPKCVKLRALHSACKFGVAARSCQELLRKGCVRFQLPMPGSRLCLYEDGTEVTDDCFPGLPNDAELLLLTAGETWHGYVSDITRFLSVFNEPHAGVIQAARQLLSDEQAPLRQKLLADLLHHVSQNITAETREQDPSWFEGLESRFRNKSGYLRYSCESRIRGYLREVSAYTSMVDEAAQEEYLRVLGSMCQKLKSVQYNGSYFDRGAEASSRLCTPEGWFSCQGPFDLESCLSKHSINPYGNRESRILFSTWNLDHIIEKKRTVVPTLAEAIQ--DGREVNWEYFYSLLFTAENLKLVHIACHKKTTHKLECDRSRIYRPQTGSRRKQPARK----KRPARKR-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99N34-1", "uniprot_id": "DFFB_RAT", "id": "Q99N34-1", "name": "DNA fragmentation factor subunit beta", "aln": "MCAVLPQPKCVKLRALHSSCKFGVAARSCQELLRKGCIRFQLPVPGSRLCMYEDGTEVTDDCFPSLPNDSELLLLTAGETWHGYVSDITRLLSVFNEPHAGVIQAARQLLSDEQAPLRQKLLADLLHHVSQNITAETREQDPSWFEGLESRFRNKSGYLRYSCESRIRGYLREVSAYISMVDAAAREEYLRVLSSMCHKLKSVQYNGSYFDRGAEASSRLCTPEGWFSCQGPFDLESCLSKHSINPYGNRESRILFSTWNLDHIIEKKRTVVPTLAEAIQ--DGREVNWEYFYSLLFTAENLKLVHIACHKKTTHKLQCDRSRIYRPQTGSRRKQPPRKQPPRKRPPRKRQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O76075-1", "uniprot_id": "DFFB_HUMAN", "id": "O76075-1", "name": "DNA fragmentation factor subunit beta", "aln": "---MLQKPKSVKLRALRSPRKFGVAGRSCQEVLRKGCLRFQLPERGSRLCLYEDGTELTEDYFPSVPDNAELVLLTLGQAWQGYVSDIRRFLSAFHEPQVGLIQAAQQLLCDEQAPQRQRLLADLLHNVSQNIAAETRAEDPPWFEGLESRFQSKSGYLRYSCESRIRSYLREVSSYPSTVGAEAQEEFLRVLGSMCQRLRSMQYNGSYFDRGAKGGSRLCTPEGWFSCQGPFDMDSCLSRHSINPYSNRESRILFSTWNLDHIIEKKRTIIPTLVEAIKEQDGREVDWEYFYGLLFTSENLKLVHIVCHKKTTHKLNCDPSRIYKPQTRLKRKQPVRK--------RQ--", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* :**.******:*. *****.*****:*****:***** *****:******:*:* **.:*:::**:*** *::*:****** *:**.*:**:.*:****:***.***** **:*******:*****:**** :**.*********:.**************.******:* * *. *:**:****.***::*:*:***********:..*****************::****:******.**********************::***.***: *****:*****.****:********.*********:** ****:*** :**** ** *: ", "identical_positions": 255, "similar_positions": 64, "identity": "72.65%" }, { "cls_id": "homologset.agr.MGI:1196288", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O55135-1", "uniprot_id": "IF6_MOUSE", "id": "O55135-1", "name": "Eukaryotic translation initiation factor 6", "aln": "MAVRASFENNCEVGCFAKLTNAYCLVAIGGSENFYSVFEGELSDAIPVVHASIAGCRIIGR--MCVGNRHGLLVPNNTTDQELQHIRNSLPDSVQIRRVEERLSALGNVTTCNDYVALVHPDLDRETEEILADVLKVEVFRQTVADQVLVGSYCVFSNQGGLVHPKTSIEDQDELSSLLQVPLVAGTVNRGSEVIAAGMVVNDWCAFCGLDTTSTELSVVESVFKLNEAKPSTIATSMRDSLIDSLT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q3KRD8-1", "uniprot_id": "IF6_RAT", "id": "Q3KRD8-1", "name": "Eukaryotic translation initiation factor 6", "aln": "MAVRASFENNCEVGCFAKLTNTYCLVAIGGSENFYSVFEGELSDTIPVVHASIAGCRIIGR--MCVGNRHGLLVPNNTTDQELQHIRNSLPDSVQIRRVEERLSALGNVTTCNDYVALVHPDLDRETEEILADVLKVEVFRQTVADQVLVGSYCVFSNQGGLVHPKTSIEDQDELSSLLQVPLVAGTVNRGSEVIAAGMVVNDWCAFCGLDTTSTELSVVESVFKLNEAKPSTIATSMRDSLIDSLT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6AC66-1", "uniprot_id": "A0A8I6AC66_RAT", "id": "A0A8I6AC66-1", "name": "Eukaryotic translation initiation factor 6", "aln": "MVVRASFENNCEVSCFARLTNTYSLVAIGGSENFYSVFEGELSDTIPVVHASIASCRIIGRGTSVWGTGMGYWYPTTTTDQELQHIHDSLLDSVQIRRVEEGLSALDNVTTCNDYVALVHPDLDRETEEILAGVLKVEVL--TVADQVLVGSYCVFSNQGGLVYPKTSIEDQDELSSPLQVPLVAGTVNRGSEVIAAGMVVNDWCAFCGLDTTSTELSVVESVFKLNEAKPSTIATSMRDSLIDRLT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P56537-1", "uniprot_id": "IF6_HUMAN", "id": "P56537-1", "name": "Eukaryotic translation initiation factor 6", "aln": "MAVRASFENNCEIGCFAKLTNTYCLVAIGGSENFYSVFEGELSDTIPVVHASIAGCRIIGR--MCVGNRHGLLVPNNTTDQELQHIRNSLPDTVQIRRVEERLSALGNVTTCNDYVALVHPDLDRETEEILADVLKVEVFRQTVADQVLVGSYCVFSNQGGLVHPKTSIEDQDELSSLLQVPLVAGTVNRGSEVIAAGMVVNDWCAFCGLDTTSTELSVVESVFKLNEAQPSTIATSMRDSLIDSLT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6ZM19-1", "uniprot_id": "IF6_DANRE", "id": "Q6ZM19-1", "name": "Eukaryotic translation initiation factor 6", "aln": "MAVRASFEKNNEIGCFAKLTNTYCLVAIGGSENFYSVFEGELSETMPVIHASIAGCRIIGR--MCVGNRHGLLVPNNTTDQELQHIRNCLPDSVRIQRVEERLSALGNVIACNDYVALVHPDLDRETEEILADTLKVEVFRQTVAEQVLVGSYCAFSNQGGLVHAKTSIEDQDELSSLLQVPLVAGTVNRGSEVIAAGMVVNDWCAFCGLDTTSTELSVIESVFRLSETQPSAIATTMRDSLIDSLT", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P56538-1", "uniprot_id": "IF6_DROME", "id": "P56538-1", "name": "Eukaryotic translation initiation factor 6", "aln": "MALRVQFENNDDIGVFTKLTNTYCLVAIGGSETFYSAFEAELGDTIPVVHANVGGCRIIGR--LTVGNRNGLLVPNSTTDEELQHLRNSLPDAVKIYRVEERLSALGNVIACNDYVALVHPDLDKETEEIIADVLKVEVFRQTIADNSLVGSYAVLSNQGGMVHPKTSIQDQDELSSLLQVPLVAGTVNRGSEVLAAGMVVNDWLSFVGMNTTATEISVIESVFKLNQAQPATVTTKLRAALIEDMS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12522-1", "uniprot_id": "IF6_YEAST", "id": "Q12522-1", "name": "Eukaryotic translation initiation factor 6", "aln": "MATRTQFENSNEIGVFSKLTNTYCLVAVGGSENFYSAFEAELGDAIPIVHTTIAGTRIIGR--MTAGNRRGLLVPTQTTDQELQHLRNSLPDSVKIQRVEERLSALGNVICCNDYVALVHPDIDRETEELISDVLGVEVFRQTISGNILVGSYCSLSNQGGLVHPQTSVQDQEELSSLLQVPLVAGTVNRGSSVVGAGMVVNDYLAVTGLDTTAPELSVIESIFRLQDAQPESISGNLRDTLIETYS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. *..**:. ::. *::***:*.***:****.***.**.**.:::*::*:.:.. ***** *. * *. ***:****:::.* *:*:* **** ****.** ***********:*:****:::..* ***: *:: : *****. :*****:*:.:**::**:**** **************.*:.*******: :. *::**:.*:**:**:*:*.:::* ::: .:* :**: :", "identical_positions": 130, "similar_positions": 83, "identity": "52.63%" }, { "cls_id": "homologset.agr.MGI:1196293", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GK03-1", "uniprot_id": "A0A8I6GK03_RAT", "id": "A0A8I6GK03-1", "name": "Gamma-tubulin complex component", "aln": "MIHELLLALSGYPGSIFTWNKRSGLQVSQDFPFLHPSETSVLNRLCRLGTDYIRFTEFIEQYTGHVQQQDHHPSQQGQGGLHGIYLRAFCTGLDSVLQPYRQALLDLEQEFLADPHLSISHVNYSLDQFQLLFPSVMVVVEQIKSQKIHGCQILETVYKHSCGGLPPVRSALEKILAVCHGVMYKQLSAWMLHGLLLDQHEEFFIKQGPSSGNVSAQMEEDEEDLGIGGLTGKQLRELQDLRLIEEENMLAPSLKQFSLRVEILPSYIPVRVAEKILFVGESVQMFEN-QNVNLTRKGS----------------ILKNQEDTFAAELHRLKQQPLFSLVDFEQVVDGIRSTVAEHLWKLMVEESDLLGQLKIIKDFYLLGRGELFQAFIDTAQHMLKTPPTAVTEHDVNVAFQQSAHKVLLDDDNLLPLLHLTIEYHGKDHKADATQPREVPSRETSPREPPSSGWAALGLSYKVQWPLHILFTPAVLEKYNVVFKYLLSVRRVQAELQHCWALQMQR-KHLKSNQTDAVKWRLRNHMAFLVDNLQYYLQVDVLESQFSQLLHQINSTRDFESIRLAHDHFLSNLLAQSFILLK--------------PVFHCLNEILDLCHSFCSLVSQNLGPLDERGAAQLSILVKGFSRQSSLLFKILSSVRNHQINSDLAQLLLRLDYNKYYTQAGGTLGSFGM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D4F8-1", "uniprot_id": "GCP4_MOUSE", "id": "Q9D4F8-1", "name": "Gamma-tubulin complex component 4", "aln": "MIHELLLALSGYPGSIFTWNKRSGLQVSQDFPFLHPSETSVLNRLCRLGTDYIRFTEFIEQYTGHVQQQDHHPPQQGQGGLHGIYLRAFCTGLDSVLQPYRQALLDLEQEFLADPHLSISHVNYSLDQFQLLFPSVMVVVEQIKSQKIHGCQILETVYKHSCGGLPPVRSALEKILAVCHGVMYKQLSAWMLHGLLLDQHEEFFIKQGPSSGTLSAQLEEDEEDLGIGGLTGKQLRELQDLRLIEEENMLAPSLKQFSLRVEILPSYIPVRVAEKILFVGESVQMFEN-QNVNLTRKGS----------------ILKNQEDTFAAELHRLKQQPLFSLVDFEQVVDRIRSTVAEHLWKLMVEESDLLGQLKIIKDFYLLGRGELFQAFIDTAQHMLKTPPTAVTEHDVNVAFQQSAHKVLLDDDNLLPLLHLTIEYHGKDHKADATQPREVPSRETSPREAPSSGWAALGLSYKVQWPLHILFTPAVLEKYNVVFKYLLSVRRVQAELQHCWALQMQR-KHLKSNQTDAVKWRLRNHMAFLVDNLQYYLQVDVLESQFSQLLHQINSTRDFESIRLAHDHFLSNLLAQSFILLK--------------PVFHCLNEILDLCHSFCSLVSQNLGPLDERGAAQLSILVKGFSRQSSLLFKILSSVRNHQINSDLAQLLLRLDYNKYYTQAGGTLGSFGM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UGJ1-1", "uniprot_id": "GCP4_HUMAN", "id": "Q9UGJ1-1", "name": "Gamma-tubulin complex component 4", "aln": "MIHELLLALSGYPGSIFTWNKRSGLQVSQDFPFLHPSETSVLNRLCRLGTDYIRFTEFIEQYTGHVQQQDHHPSQQGQGGLHGIYLRAFCTGLDSVLQPYRQALLDLEQEFLGDPHLSISHVNYFLDQFQLLFPSVMVVVEQIKSQKIHGCQILETVYKHSCGGLPPVRSALEKILAVCHGVMYKQLSAWMLHGLLLDQHEEFFIKQGPSSGNVSAQPEEDEEDLGIGGLTGKQLRELQDLRLIEEENMLAPSLKQFSLRVEILPSYIPVRVAEKILFVGESVQMFEN-QNVNLTRKGS----------------ILKNQEDTFAAELHRLKQQPLFSLVDFEQVVDRIRSTVAEHLWKLMVEESDLLGQLKIIKDFYLLGRGELFQAFIDTAQHMLKTPPTAVTEHDVNVAFQQSAHKVLLDDDNLLPLLHLTIEYHGKEHKADATQAREGPSRETSPREAPASGWAALGLSYKVQWPLHILFTPAVLEKYNVVFKYLLSVRRVQAELQHCWALQMQR-KHLKSNQTDAIKWRLRNHMAFLVDNLQYYLQVDVLESQFSQLLHQINSTRDFESIRLAHDHFLSNLLAQSFILLK--------------PVFHCLNEILDLCHSFCSLVSQNLGPLDERGAAQLSILVKGFSRQSSLLFKILSSVRNHQINSDLAQLLLRLDYNKYYTQAGGTLGSFGM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VKU7-1", "uniprot_id": "GCP4_DROME", "id": "Q9VKU7-1", "name": "Gamma-tubulin complex component 4 homolog", "aln": "MIHDLLLACRSHNPEQLGIKAFN--ETTVIDQFIHPCEREIFMDIIKIIKVYQEVEQFTHSSGRKSDTHGELP-----DSLHGYYLLNLAKGIEMALEEYYAEIGRLEKYCLGNERNSLSYVYNALYAKFPLLVFMRNLITEIHVLNLRGCVLLHNLHQQCEHGDIQLEKAIKIIMKPVKNAFFSSLAHWLLFGVIDDVHSEFFIKFTPT-----------------DAVDGSSFSKSATCSLLSAEKNPEDYIWQYEVNMSQLPGFFSIVLAEKVLFVGQTVLVFKMGRNVKVKNKTDPLAAKLAELDSDDIYQLWSGRESEFFKMVVDLSNEDTINVFRLEKVIIDIKNYVSARLSEIAVNEVDLERQMGLIKDFFLLGRGEFYLEFCSQMVGTMETYREERFKN-VTRSFELAATVTGITDD----LDKFSLICQRSTSEPDDTSDFNFLQG--------------LSLKYEYEWPLNLLFSPTTIERYNNIFRFLLIIRTYQYEIQRVWAKQTWRAKSAKDVPPNNKIITLRNYLMFFLNNMQYYIQVDVLESQFGILMNVIKSRSDFEVIQRAHTVFLANVLSHCFLLNESETQLNVTGSQNRNPIYGTLLKLFGICEKFAHMTQTKD--PSDDLEDEVDQLNESFGVQIASLIQLLVDVKSASCLGPLSQLLLRLDFNCWFSASHNTSA----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***:**** .: . : : . :.: *:**.* .:: : :: . * .. :* .. : : :.. * ..*** ** :..*:: .*: * : **: *.: : *:*:* * *: : :: :*: :::** :*..::::. * :..*:: *: :..::..*: *:*.*:: * *.***** *: ..: *..: : *:. *: : *:.:.:. **.::.: :***:****::* :*: :**::..* . : ..:*. * : *.:: :.:. :*:*: *:. *: :* :: *:* ** *: :****:******:: * . ::* :: *. :*: :* . : ** * :::: : . :.* *. : . *.*.*: :***::**:*:.:*:** :*::** :* * *:*: ** * * * *. .: ***:: *:::*:***:*********. *:: *:* *** *: ** **:*:*::.*:* : *:: * :::.:*..*. :.. : .: ::. * :.*. * : *:::* .*:. . . *:*******:* ::: : .* . ", "identical_positions": 177, "similar_positions": 244, "identity": "25.32%" }, { "cls_id": "homologset.agr.MGI:1196294", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q32PX7-1", "uniprot_id": "FUBP1_RAT", "id": "Q32PX7-1", "name": "Far upstream element-binding protein 1", "aln": "MADYSTVPPPSSGSAGGGGGGG----VNDAFKDALQRARQIAAKIG----GDAG-TSLNSNDYGYGGQKRPLEDGDQPDAKKVPPQNDSFGAQLPPMH--------------------------------QQQ-RSVMTEEYKVPDGMVGFIIGRGG-EQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPESVQSAKRLLDQIVEKGR--------PAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGADKPLRITGDPYKVQQAKEMVLELIRDQGGFREVRNEYGSRIGGN---------------EGIDVPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKP-DDGTTPDRIAQITGPPDRCQHAAEIITDLLRSVQAGNP------GGPGPGGRGRGRGQGNWNMGP-----PGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKIGGPVNPLG-PPVPHGPHGVPGPHGPP-GPPGPGTPMGPYNPAPYNPG-----PPGPAPHGPPAPYAPQGWGNAYPHWQQQAPP-----DPAKAGTDPNSAAWAAYYAHYYQQQAQPPPAAPAGAPTTTQTNGQGDQQNPAP------------AGQVDYTKAWEEYYKKMG-------------------------------------------QAVPAPAGAPPGGQPDYSAAWAEYYRQQAAYYAQTSPQGMPQHPPAPQGQ--------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91WJ8-1", "uniprot_id": "FUBP1_MOUSE", "id": "Q91WJ8-1", "name": "Far upstream element-binding protein 1", "aln": "MADYSTVPPPSSGSAGGGGGGV----VNDAFKDALQRARQIAAKIG----GDAG-TSLNSNDYGYGGQKRPLEDGDQPDAKKVPPQNDSFGAQLPPMH--------------------------------QQQSRSVMTEEYKVPDGMVGFIIGRGG-EQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPESVQSAKRLLDQIVEKGR--------PAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGADKPLRITGDPYKVQQAKEMVLELIRDQGGFREVRNEYGSRIGGN---------------EGIDVPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKP-DDGTTPDRIAQITGPPDRCQHAAEIITDLLRSVQAGNP------GGPGPGGRGRGRGQGNWNMGP-----PGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQSGARIELQRSPPPNADPNMKLFTIRGTPQQIDYARQLIEEKIGGPVNPLG-PPVPHGPHGVPGPHGPP-GPPGPGTPMGPYNPAPYNPG-----PPGPAPHGPPAPYAPQGWGNAYPHWQQQAPP-----DPAKAGADPNSAAWAAYYAHYYQQQAQPPPAAPAGAPATTQTNGQGDQQAPAP------------AGQVDYTKAWEEYYKKMG-------------------------------------------QAVPAPAGAPPGGQPDYSAAWAEYYRQQAAYYAQTSPQGMPQHPPAPQGFANHARSHHHLY---------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96AE4-1", "uniprot_id": "FUBP1_HUMAN", "id": "Q96AE4-1", "name": "Far upstream element-binding protein 1", "aln": "MADYSTVPPPSSGSAGGGGGGGGGGGVNDAFKDALQRARQIAAKIG----GDAG-TSLNSNDYGYGGQKRPLEDGDQPDAKKVAPQNDSFGTQLPPMH--------------------------------QQQSRSVMTEEYKVPDGMVGFIIGRGG-EQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPESVQSAKRLLDQIVEKGR--------PAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGADKPLRITGDPYKVQQAKEMVLELIRDQGGFREVRNEYGSRIGGN---------------EGIDVPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKP-DDGTTPERIAQITGPPDRCQHAAEIITDLLRSVQAGNP------GGPGPGGRGRGRGQGNWNMGP-----PGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKIGGPVNPLG-PPVPHGPHGVPGPHGPP-GPPGPGTPMGPYNPAPYNPG-----PPGPAPHGPPAPYAPQGWGNAYPHWQQQAPP-----DPAKAGTDPNSAAWAAYYAHYYQQQAQPPPAAPAGAPTTTQTNGQGDQQNPAP------------AGQVDYTKAWEEYYKKMG-------------------------------------------QAVPAPTGAPPGGQPDYSAAWAEYYRQQAAYYAQTSPQGMPQHPPAPQGQ--------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TXQ2-1", "uniprot_id": "A0AB32TXQ2_DANRE", "id": "A0AB32TXQ2-1", "name": "", "aln": "MADYSNVAPPSS-NAGGG--------MNDAFKDALQRARQIAAKIG----GDGVPPSPVSNDFGYGGQKRPLEDGDQPETKKVPP-SDPFSAVMGGMG--------------------------------GPP-RSVS-EEFKVPDGMVGFIIGRGG-EQISRLQQESGCKIQIAPDSGGMPDRSVTLTGSPDAIMTAKRLLSEIVEKGR--------PSPAFHHNDGPGMSVHEMMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGADKPLRISGDPFKVQQAKDMVMDLIRDQG-FREQRGEYGSRAGGGGGGG-----------ESLDVPVPRFAVGIVIGRSGEMIKKIQNDTGVRIQFKP-DDGSTPERIAQIMGPPDRAQHAADIITDLLRSVQAGGPPGHGGGGGGGGGGRGRGRGQGNWNMGP-----PGGLQEFTFTVPTMKTGLIIGKGGETIKNISQQSGARIELQRNPPPNSDPNIKIFTVRGSPQQIDYARQLVEEKIGGPVSPMGGPHGPPGPHGGP-SHGPP-GPQGPPAPMGPYNPGPYGQG-----PPG--PHGPPAPYQPQGWGNGYPHWQQGQPDPT-VCSPDKAAADANAAAWAAYYSQY-QQQPQGPMTPTSAAPGTTQANGQGDPQAPGQ------------SGQADNTKAWEEYYKKLGQGQPQQDYTKAWEEYYKKQG----------------ELSQAAPQAAAAATATQPGGQPDYSAAWAEYYRQQAAYYGQGAPQAMGGAPQAQQGQ--------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1ZAK8-1", "uniprot_id": "A1ZAK8_DROME", "id": "A1ZAK8-1", "name": "", "aln": "MSDFQQQGINQS----------------QALAQAIQRAKQIAAKIQPSQQGGGTAGPSPPSSGGGPGFKRINDDGDSGPESKRSLGSPEYANNSSNMSSGSGGGGGGGGGPGGASITQAIAQAAAVAARLAASAGTSCEEQIRLPESVAGAFMGRSSNDTITHIQAESGVKVQVMQDQ----DRVIMLRGQRDTVTKGREMIQNMANRAGGGQVEVLLTINMPPPGPSGYPPYQEIMIPGAKVGLVIGKGGDTIKQLQEKTGAKMIIIQDGP-NQELIKPLRISGEAQKIEHAKQMVLDLIAQKDAQGQQQGGRGGGGGGGGPGMGFNNFNNGNGGESTEVFVPKIAVGVVIGKGGDMIRKIQTECGCKLQFIQGKNDEMGDRRCVIQGTRQQVDDAKRTIDGLIENVMQRNGMNR--NGNGGGGGPGGDSGNSNYGYGYGVNHAQGGREEITFLVPASKCGIVIGRGGETIKLINQQSGAHTEMDRN--ASNPPNEKLFKSKGTTDQVEAARQMISEKINMELNVISRKPIGGGPGGGGGNSGGGQNNSHHNQQQGGYGGQNQMQGGDPNSGAGYQQQPWGGPYGQQGWDPSGQQQQMAMANQGGSAAGGASGGQDYSAQWIEYYKQMGCHREAEMIEQQMKAKQAGGSSGPVQQQQPQQQQQSQQQTGGAGAGGADYSAQWAEYYRSVGKIEEAEAIEKTLKNKQQNGSGGQSSTPNPSQGGSGQQQPNPAAAAAAAAAAAAAAGGYGQSMTPTQYAQYSQYYAAAAAAGGQPQGAPQPGGGQSGGPPGNYPGNYPGAGYGGYPGAPGQQQQKSHKNDNH", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:*:. .* :*: :*:***:****** *.. . ... * * ** :***. .* . . :. * : *: ::*:.:.* ::**.. : *:::* *** *:*: *. :* * * ::: ..:.::.::.::. . . . . :*:***.:*.********:*******::*.**::***** * *****:*:. *:::**:**::** ::. : :. *. **. *. :* :*::***:***:.*:**:***.: * ::** .:. :* . * *. :: :.* * .*:..* . *. * ** * . *:.*:. * ** :*:.* **: * *::**:****** *.*****: *::*. .. ** *:*. :*:.:*:: ***::.***. :. :. ** * * . * *. * .* : .** ***. . : * . :. : :* * ** : :: * : :.* : * * :* .* : * ***:.:* *..*.:.: ..* . * : ::* : . * . :. . . * ", "identical_positions": 190, "similar_positions": 200, "identity": "23.11%" }, { "cls_id": "homologset.agr.MGI:1196295", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A1L1L3-1", "uniprot_id": "PTN20_RAT", "id": "A1L1L3-1", "name": "Tyrosine-protein phosphatase non-receptor type 20", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSPGNVRQKHGRDND----------------------EHEGDSDDLN---------------LQKSLPSSSQQ---------KTPTK-----PVFG------------------------------------------------------------------------------------NKVNSESVKTSH--HMSFSNKYDLVFPEP-------------------VESDNDETLWDVRDLSHRNRWS-----SVDPESAGPSKTVSTVLSESS-----TDTAVSERELTQLAQIRPLIFNSSSRAALRDCLKALQKK-EELDIIREFLELEEMIPPDDFKSGYELQNRDKNRYRDILPYDSTRVPLGKNKDYINASYIRIVNHEEEYFYIATQGPLPDTIEDFWQMVLENNCNVIAMITREIEGGVIKCCSYWPVSLKEPLEFKHFHVLLENFQITQYFVIRIFQIVKKSTGKSHSVKHLQFIKWPDHGTPASADFFIKYVRYVRKSHITGPLLVHCSAGVGRTGVFICVDVVFCTIEKNYSFNIMNIVTQMRKQRFGMIQTKEQYQFCYEIVLEVLQNLLALN----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O55082-1", "uniprot_id": "PTN20_MOUSE", "id": "O55082-1", "name": "Tyrosine-protein phosphatase non-receptor type 20", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSPRKVRGKTGRDND----------------------EEEGNSGNLN---------------LRNSLPSSSQK---------MTPTK-----PIFG------------------------------------------------------------------------------------NKMNSENVKPSH--HLSFSDKYELVYPEP-------------------LESDTDETVWDVSDRSLRNRWN-----SMDSETAGPSKTVSPVLSGSSRLSKDTETSVSEKELTQLAQIRPLIFNSSARSAMRDCLNTLQKK-EELDIIREFLELEQMTLPDDFNSGNTLQNRDKNRYRDILPYDSTRVPLGKNKDYINASYIRIVNHEEEYFYIATQGPLPETIEDFWQMVLENNCNVIAMITREIECGVIKCYSYWPISLKEPLEFEHFSVFLETFHVTQYFTVRVFQIVKKSTGKSQCVKHLQFTKWPDHGTPASADFFIKYVRYVRKSHITGPLLVHCSAGVGRTGVFICVDVVFSAIEKNYSFDIMNIVTQMRKQRCGMIQTKEQYQFCYEIVLEVLQNLLALY----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4JDL3-1", "uniprot_id": "PTN20_HUMAN", "id": "Q4JDL3-1", "name": "Tyrosine-protein phosphatase non-receptor type 20", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSPRDFRAEPVNDYE----------------------GNDSEAEDLN---------------FRETLPSSSQE---------NTPRS-----KVFE------------------------------------------------------------------------------------NKVNSEKVKLSL--RNFPHNDYEDVFEEP-------------------SESGSDPSMWTARGPFRRDRWS-----SEDEEAAGPSQALSPLLSDTR-------KIVSEGELDQLAQIRPLIFNFHEQTAIKDCLKILEEKTAAYDIMQEFMALELKNLPGEFNSGNQPSNREKNRYRDILPYDSTRVPLGKSKDYINASYIRIVNCGEEYFYIATQGPLLSTIDDFWQMVLENNSNVIAMITREIEGGIIKCYHYWPISLKKPLELKHFRVFLENYQILQYFIIRMFQVVEKSTGTSHSVKQLQFTKWPDHGTPASADSFIKYIRYARKSHLTGPMVVHCSAGIGRTGVFLCVDVVFCAIVKNCSFNIMDIVAQMREQRSGMVQTKEQYHFCYDIVLEVLRKLLTLD----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AZ90-1", "uniprot_id": "A0A8M3AZ90_DANRE", "id": "A0A8M3AZ90-1", "name": "", "aln": "MSSTFVTLAEVLEARGGPLEEDEVWSLLLGSAESLVDLSYKGHNICNIITPASLLLSATGTLAFKNCAMTDEVCAFTAPEMLQGRTVSTKLAMEKIIVYSLGMTLYWSVDYHLPQNQPIQLSDSLNCLLLSMCEDMAHRRTNLNSILEVCESHHKASLLPPPNKVIKQLVEDVLQESVDRAALTENVVQLSGKSQMIRERLHGKRGPYSGYTEMNGAAGETRRLSLDSEPKQGIFHHQKTWSLKSRPSQTTSYQSSSRNPLGLHNRRSTSFWSRSSCLNSPNKGEVRPSSPCITVSESAVSLSQRKAKSLGPEFTRMNDEPQIILELPGSIVSKKGKSGLSQREVNVIMPNEQCVAVKCDIKSRGRDVFDMVVAHANLVEHFYFGLAFIDDGEFFFLDPETKISKVAPDYWKKVASATFTLYLRVRFFPDDISYILHKHTRHQYYLQLRKDILEDRVHCNEETALFLAALALQAEFGDYMAEVYGKNYFQTEQYISKRVIEKVALPCLREELPRLHANNAQMLPEEAETEFLKIAQQLPEYGVLFHRVARERKPIIGELVLGICAKGILVYEVKNNSRMLSRRFHWTETDSLSTSRRKFTIECSPSGKKHSFVTESSKIAQYLLNLCSAQHKFHSEMTSRQLTYCLASDDSVAKYTSICRARHEQIKRLSCSEIVLNNIGLNGLPSDSISKSCDDLSAKIGVRIRQQNEVNYSPESRAPCEPKDQSQSSSPLETFSPPVYRIMSNVSLQKQDSEVHSTTSSIRVDTPTKTTPEREIICVTLKKDPKLGYGFIIVGEDNTGKLDLGIFIASIIPDGPADKDGRIRPGGRLISLNNISLEGVTFNIAASILQNSPEEVELIVSQPKQDLRGSKTSLAPSNLGMMLERSFGSQSTLSAEYRPVMEELEETLSNIMAPKINKRMHIPVVRILDIQDEMSKSSSGFSLKPGEIIYMELRKINGSLGISVAGGINTNVHHGGIYIKSVIAGGAADQDGRIQIGDRLLEVDGCNLRAVTHRQAVECLKRTGEVVSLVLEREPPVVLDTSSASSTLERRRSPSPLSAPLRRDVPLQTPLSVRTKDFRFVSDENILEVTLQKSFSGLGFSFLVSELGPEKENIVQIKSLSSGHPAGDCGLLKEGDIILAVNGEPVRGLSYEEVLHLLQKSPSEIRLSICRPSQDEHTDIETFLVPNRELRSRSLDLQARSVAPDFSELLLRRAIEMGLKKEASPEETQESELLETDKSIPPPLPPRPSSAEGGERKPHVILVEEYEKKDPPPPPTPPPTPGILKASTTNTVQTPAAPKTAIKAHQQESLEPTVSRSNHVSACTSHVKDEGVEENVISFTANGLTVTAGEEYLTISTTAPSPPSGSTAVSSEAPPPVPALSPSLLNTPPTYQQAIQAASPAEPPAQPSNNGWDDDDEEDDEDPRRDVFKEFELTVSLTKSWCGSFGFTITRSKLDNCYYVQDVLDNPAKADGRLRAGDRLIMVNGHNVTSVTDDVAISILRCSSKRLHMVLGRAVQNLLPPPPPDTLQDIIISKTPSGQLGIKLTGGIGSKRQGIYVQEVVLSSPASEEGSIQPNDKIVYICGRCTLGMTLEDAVKVCESSPRKVRFKAMRDDQPVIPRDKWNGLFEWKEKKGFPHLEEPMSPDVHSALADVKAVADSAMLFRKRLSVTAEQESCILQVEFTKPDRGGLGFALVGGVNGSTLRVKDICCGGVAEQDGRLRVGDILLEVNGIIVSGLSHSKVVDILRKAEGTVQLTVCRDILPMSACSASNYPTEAHGNFNTLNSAAQTEAHPDHVSFHSDCPECEQESRNCTPTCQRCCPSLGVTDMLQEKTDPQKQHLENSAMKTEHSQSDGWSSDEEEDGDDDDCASQPSPPETIPLTGRPIVSEEELSSLAVISPPKNGQYTGSRVKALIQALEQL-EKQDLVKEFMALEHLNPSDNCLVGKAPENREKNRYREILPYDKTRVPVGEDEGYINASYIRMKVGSEELFFISAQGPLPGTQDSFWQMVWENRSDVIAMMTREVERGRVKCHKYWPEKLDVPKETSRYQLFLDNYQMLGYFHIKVIKMVEKKSGDVHFVKHLKFTTWPDHGTPHSSDQLVRFIRYMRAVHAKGPITVHCSAGIGRAGVLICTDVILSLIQKDLSINVSDIVKEMRLQRHGMIQTKEQYLFCYKVWLEVLQNISLLYGHHWQTETSS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *** ..* : .* : .: : ::: ::: *. :::: .* :. *.:** . : : .. *. :. .* . : . . * * * * .. :. * . *** ** .** * * . : :: :: *:: *:::**: ** ..: * .**:*****:*****.****:*:.:.********: ** *:*::**** * :.***** **..:****:***:* * :** *** .*. * * .:: ::*:.::: ** ::::::*:*.:* : **:*:* .******* *:* :::::** * * .**: ******:**:**::*.**::. * *: *::: :** :** ** **:****** ***.: ****::: * ", "identical_positions": 154, "similar_positions": 132, "identity": "7.01%" }, { "cls_id": "homologset.agr.MGI:1196297", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZT54-1", "uniprot_id": "A0A8I5ZT54_RAT", "id": "A0A8I5ZT54-1", "name": "", "aln": "MTPPERAMTGGSNSRRRRAEERSSAAGAERSSPREAAGSMGAGPALALLLLAGSVLSATLLAPG------RRAEP--DLDEKRNVELKMDQALLLIHNELLGTSLTIYWKSEYCYQCTFQPLANVSHGRKPAKPSVEAVSVSTQHGSILQVNSTLEERAACRLEYKFGEFGNYSLLVRHASSGADDIACDLVVNENPVDSNLPVSIAFLVGLALVIAISILKLLLSLDDINNWISKAIASRETDRLINSELGSPSRADPLGADCQPETRRASALPHRLRCVDTFRGVALILMVFVNYGGGKYWYFKHSSWNGLTVADLVFPWFVFIMGSSIFLSMTSLLQRGCSKIKLLGKIAWRSFLLICIGIIIVNPNYCLGPLSWDKVRIPGVLQRLGVTYFVVAMLELFFWKPVPDSCTLERSCLSLRDITSSWPQWLIILILESIWLALTFFLPVPGCPTGYLGPGGIGDLGKYPHCTGGAAGYIDRLLLGDSHLYQHPSSAVLYHTEVAYDPEGVLGTINSIVMAFLGVQAGKILLYYKDQTKAILIRFAAWCCILGLISIALTKMSANEGFIPINKNLWSISYVTTLSCFAFSILLILYPVVDVKG--LWTGTPFFYPGMNSILVYVGHEVFEDYFPFQWKLEDEQSHKEHLIQNIVATALWVLIAYILYKKKVFWKI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UDW8-1", "uniprot_id": "HGNAT_MOUSE", "id": "Q3UDW8-1", "name": "Heparan-alpha-glucosaminide N-acetyltransferase", "aln": "-------MTGGSSSRRRRAEERSSAAGTERNSRREAVGGMGAGPALAALLLAGSVLSATLLAPG------RRAEP--DLDEKRNVELKMDQALLLIHNELLGTSLTVYWKSDDCYQCTFQPLANVSHGGKPAKPSVAPVSVSTQHGSILQVNSTSEERAACRLEYKFGEFGNYSLLVQHASSGANKIACDIIVNENPVDSNLPVSIAFLVGLALIVAVSLLRLLLSLDDVNNWISKTIASRETDRLINSELGSPSRADPLSADYQPETRRSSAN--RLRCVDTFRGLALVLMVFVNYGGGKYWYFKHSSWNGLTVADLVFPWFVFIMGTSIFLSMTSILQRGCSKLKLLGKIVWRSFLLICIGVIIVNPNYCLGPLSWDKVRIPGVLQRLGVTYFVVAVLEFFFWKPVPDSCTLESSCFSLRDITSSWPQWLTILTLESIWLALTFFLPVPGCPTGYLGPGGIGDLGKYPHCTGGAAGYIDRLLLGDNHLYQHPSSTVLYHTEVAYDPEGVLGTINSIVMAFLGVQAGKILVYYKDQTKAILTRFAAWCCILGLISIVLTKVSANEGFIPINKNLWSISYVTTLSCFAFFILLILYPVVDVKG--LWTGTPFFYPGMNSILVYVGHEVLENYFPFQWKLADEQSHKEHLIQNIVATALWVLIAYVLYKKKLFWKI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q68CP4-1", "uniprot_id": "HGNAT_HUMAN", "id": "Q68CP4-1", "name": "Heparan-alpha-glucosaminide N-acetyltransferase", "aln": "-------MTG---ARASAAEQRRAGRSGQARAAERAAGMSGAGRALAALLLAASVLSAALLAPGGSSGRDAQAAPPRDLDKKRHAELKMDQALLLIHNELLWTNLTVYWKSECCYHCLFQVLVNVPQSPKAGKPSAAAASVSTQHGSILQLNDTLEEKEVCRLEYRFGEFGNYSLLVKNIHNGVSEIACDLAVNEDPVDSNLPVSIAFLIGLAVIIVISFLRLLLSLDDFNNWISKAISSRETDRLINSELGSPSRTDPLDGDVQPATWRLSALPPRLRSVDTFRGIALILMVFVNYGGGKYWYFKHASWNGLTVADLVFPWFVFIMGSSIFLSMTSILQRGCSKFRLLGKIAWRSFLLICIGIIIVNPNYCLGPLSWDKVRIPGVLQRLGVTYFVVAVLELLFAKPVPEHCASERSCLSLRDITSSWPQWLLILVLEGLWLGLTFLLPVPGCPTGYLGPGGIGDFGKYPNCTGGAAGYIDRLLLGDDHLYQHPSSAVLYHTEVAYDPEGILGTINSIVMAFLGVQAGKILLYYKARTKDILIRFTAWCCILGLISVALTKVSENEGFIPVNKNLWSLSYVTTLSSFAFFILLVLYPVVDVKG--LWTGTPFFYPGMNSILVYVGHEVFENYFPFQWKLKDNQSHKEHLTQNIVATALWVLIAYILYRKKIFWKI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB40EBS8-1", "uniprot_id": "A0AB40EBS8_DANRE", "id": "A0AB40EBS8-1", "name": "", "aln": "-----------------MASEREN-----------------RWTICAVIVFLIAICAAHMTDRP------ASSRP-----HRKTSVLKMDEAALSVINEVE-EEMVLYVLSDHCYQCLPQPLGMIPARPTSGTPASVGFVVGTQHALTLLINSTTTP-QQCKVNFHFGEQGNYSLWVKNLNE-PSQINCEMITDSDPINSYLPILFAFLVFAFLAALSAIWSTVKRLDAVTNLLIRLGGTVETERLINSELGTPNR----LVDASTESIIPATTGRRLRSLDTFRGLSLVIMVFVNYGGGRYWFFRHESWNGLTVADLVFPWFVFIMGTSIGLSLSGSLRRGVKRTHLLWKVFWRSLQLFLIGVIIINPNYCQGPLSWDSLRIPGVLQRLGFTYLIVAALDLAVSPDRLTNLSSETCWYWVHDICLYWPAWLCVIILETVWLCLTFLLPVPGCPTGYLGPGGIGDFGQYQNCTGGAAGYIDRWLLKDNHIYQTPSSRVLYLTTMPFDPEGVLGSINSILMAFLGLQAGKILLHYRDQHRQIITRFLMWGLILGIISAVLTKCSRNDGFIPVNKNLWSLSYVTTLSCFAFVALVFFYYTVDVKK--WWSGAPFFYPGMNSILVYVGHEVFEEYFPFRWKMANSQSHTEHLAQNLLATSIWVFIAFLLYRKKIFWKI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W4F7-1", "uniprot_id": "Q9W4F7_DROME", "id": "Q9W4F7-1", "name": "", "aln": "---------------MSLFVEYTEPKWRHLDMR----------------------------------------------------ALSVDEFYLYLRSEFS-SQTHLYSLSDECYTCPYTKVKALP-AADVAAVVVEPLRLSSAYSLNFKIFDLDQGHYAYDNVSSLCWLRRSDLQEFGVYNLTLQANGTCAFAVD--KPGVPINYAFIAVFVLVAALLIALKLVSCAWRYYRYDEATAA---------------------ADSIGEAATKATQRKRLRSLDTFRGISIVLMIFVNSGGGGYAWIEHAAWNGLHLADVVFPSFLWIMGVCIPLSVKSQLSRGSSKARICLRILWRSIKLFVIGLCLN----SMSGPNLEQLRIMGVLQRFGVAYLVVAILHTLCCRREPISPQ-RSWQRAVHDVCLFSGELAVLLALVATYLGLTFGLRVPGCPRGYLGPGGKHDYNAHPKCIGGAAGYADLQVLGNAHIYQHPTAKYVYD-STAFDPEGIFGCILSVVQVLLGAFAGVTLLVHPN-FQSRIRRWTLLAILLGLIGGALCGFSREGGAIPMNKNLWSLSFVCVTVSLALLILSLMYYFIDVRETWSWSGYPFTECGMNAIVMYVGHSVLHKMLPWHWRIGEMNTHFMLLLEATWNTLVWVGIALYLDAQEFYYSV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *.:*: * : .*. . :* *: ** * : :. . :.: :. : : . : . .* . . : .. :*: **: : : : . .: * : :: ***.:*****:::::*:*** *** * ::.* :**** :**:*** *::*** .* **:.. * ** .: :: :: ***: *: **: : . . . :.:** *****:*.:*::** *. . ::*: :: * :* *** * ***** ******* * . : :* ****** * :* : *:** *:: :* .:****::* * *:: .:** ** *: : : : *: :**:*. .* * : * **:******:*:* . .:*: * .:* :**: *:* ** ***:*::****.*:.. :*::*:: : ::* * : * :** ** * ::.::.:", "identical_positions": 159, "similar_positions": 154, "identity": "23.56%" }, { "cls_id": "homologset.agr.MGI:1196310", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K1C0-1", "uniprot_id": "ANGE2_MOUSE", "id": "Q8K1C0-1", "name": "RNA 2',3'-cyclic phosphatase ANGEL2", "aln": "METWRCVRRGYGRCVAGRGRYSMFPYPLKSLGRDWTTPWEDLQKYCWRRHISSCLRWPG-HYSRAPYPYFSSRHFSLNCRPPFLFESGTQFQYYNWRSD-HLSNASLIHLSRHVMTSDRDEPLSKRRK-HQGTIKR----------------NWEYLCSHN-----------KENTKDLEDRNVDSTCEDREDK------FDFSVMSYNILSQDLLEDNSHLYRHCRRPVLHWSFRFPNILKEIKHFDADVLCLQEVQEDHYGTEIRPSLESLG--YHCEYKMKTGRKPDGCAICFKHSRFSLLSVNPVEFCRRDIP-----LLDRDNIGLVLLLQPK-IPRAASPSICIANTHLLYNPRRGDIKLTQLAMLLAEIANVTHRKDGSSCPIVMCGDFNSVPGSPLYSFIKEGKLNYEG-----LAIGKVSGQEQSSRGQRILSIPIWPPNLGISQNCVYEAQQVPKVEKTDSDVTQAQQEKAEVPVSADKVSSHLQHGFSLSSVYSHYVP-DTGVPEVTTCHSRSAITVDYIFYTAKKENTAQGPGAEVALVGG---LKLLARLSLLTEQDLWTVNGLPNEHNSSDHLPLLAKFRLEL---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1LT13-1", "uniprot_id": "F1LT13_RAT", "id": "F1LT13-1", "name": "", "aln": "METWRCVRRGYGRCVAGRGRYSMLPYPLKSLGRDWTTPWEDLQKYCWRRHISSCLRWPG-HYSRAPYPYFSSRHFSLNCRPPFLFESGTQFQYYNWRPD-QLSNTSLFHLSRYVMNSDRDEPSSKRRK-HQGTIKR----------------SWEYLCSHN-----------KEKTKDLEDRNGDSTCEDCEDK------FDFSVMSYNILSQELLEDNSHLYRHCRRPVLHWSFRFPNILKEIKHFDADVLCLQEVQEDHYGTEIRPSLESLG--YHCEYKMKTGRKPDGCAICFKHSKFSLLSVNPVEFCRRDIP-----LLDRDNIGLVLLLQPK-IPRAASPSICIANTHLLYNPRRGDIKLTQLAMLLAEISNVAHQKDGSFCPIVMCGDFNSVPGSPLYSFIKEGKLNYEG-----LAIGKVSGQEQSSRGQRILSIPIWPPNLGISQNCVYEAQQVPKVEKTDSDVTQAQQEKAEVPVPADKVSSHLQHGFSLSSVYSHYVP-DTGVPEVTTCHSRSAITVDYIFYSAEKDDTARGPGAEVALVGG---LKLLARLSLLTEQDLWTVNGLPNEHNSSDHLPLLAKFRLEL---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5VTE6-1", "uniprot_id": "ANGE2_HUMAN", "id": "Q5VTE6-1", "name": "RNA 2',3'-cyclic phosphatase ANGEL2", "aln": "MEAWRCVRKGYGHCVVGRGRYPMFPHHSRSLGRDWTTPWENLQRCCWNRHISSCMRWPG-HYSRAPYPYFSSRHFSLNWRPPCLFESRTQFQYCNWRPD-NLSQTSLIHLSSYVMNAEGDEPSSKRRK-HQGVIKR----------------NWEYICSHD-----------KEKTKILGDKNVDPKCEDSENK------FDFSVMSYNILSQDLLEDNSHLYRHCRRPVLHWSFRFPNILKEIKHFDADVLCLQEVQEDHYGAEIRPSLESLG--YHCEYKMRTGRKPDGCAICFKHSKFSLLSVNPVEFFRPDIS-----LLDRDNVGLVLLLQPK-IPYAACPAICVANTHLLYNPRRGDIKLTQLAMLLAEISSVAHQKDGSFCPIVMCGDFNSVPGSPLYSFIKEGKLNYEG-----LPIGKVSGQEQSSRGQRILSIPIWPPNLGISQNCVYEVQQVPKVEKTDSDLTQTQLKQTEVLVTAEKLSSNLQHHFSLSSVYSHYFP-DTGIPEVTTCHSRSAITVDYIFYSAEKEDVAGHPGAEVALVGG---LKLLARLSLLTEQDLWTVNGLPNENNSSDHLPLLAKFRLEL---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5RGT6-1", "uniprot_id": "ANGE2_DANRE", "id": "Q5RGT6-1", "name": "RNA 2',3'-cyclic phosphatase angel2", "aln": "MRKGRHMPRHTNANYARPGVSPNHPMFGRYLSTVGFPPAQNVYNHWRHWYQPGHLWWTQPPQLQHPSSSFSTVRHPFNRPP----RPPDPYQWSSWRQTGVLPHTRGLHLSAGLMESTDRPPPQKRRKSAEGEISQRSPQHSPPKGSRSPKGSPEWLRNVSSIEVANRTSAVPELKRHWEDLSHLCKAAPSVNRGKQKWPFDFSVMSYNILSQDLLCDNTYLYRHCNPPVLDWRNRFPNIIKELEQYSADIMCLQEVQEDHYKQQIKPSLESLG--YHCEFKRRTGLKPDGCAVIFKRERFSLVSCHPVEYFRRGVP-----LMDRDNVGLIVLLRPI-DPHVSLSNICVANTHLLYNPRRGDIKLAQLAMLLAEISRVSQLPDSSVCPVLLCGDFNSVPWSPLYRFIKDRRLDYDG-----MPIGKVSGQEETPRGQRILTVPIWPRSLGISQQCQYENQTR------DSELRDLEQTERESFTEAS-----IEHCLRLTSAYSHHLK-ESGQPEITTCHSRTAITVDYIFYSAALGDVMAQAEYSAPPERG---LQLLGRLALVGEKELQKVNGLPNQHNSSDHLPLLTRFRLHPQADS-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24239-1", "uniprot_id": "ANGEL_DROME", "id": "Q24239-1", "name": "Protein angel", "aln": "-------------------------------------------------------------------------------------------MYRSLLHN--VSLKATSRIIRRSVSSQAKGASGKRKQKAKEMESS------------------------------------HDRNRRWTSLGNQAEGRDPHKCS------SFKVVSYNILAQDLLLEHLFLYVGIPHEFLSWQRRQQNLLRELLKLDPDILCLQEMQFDHLPVLVQRLRMGNGKKLAYVYKKKTGCRTDGCAIVYDSSKFELLDHQAVELYDQAVA-----LLNRDNVALFARFRFK-KQQEQQKEFVVATTHLLFNTKRSDVRCAQVERILEELQSFSTDT-----PIVLTGDFNSLPDSSPIEFLVGKNGDVDS-----TACPEPLHFEIIDSGE-----------------------------------------------------------------------------GTASTYQNEWVIVDYILRSLG-----------SRSRHK---LLPLSVYSLPSINRCIGAGQIPNYRLGSDHYALGAVFTVV----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q03210-1", "uniprot_id": "NGL3_YEAST", "id": "Q03210-1", "name": "Probable RNA exonuclease NGL3", "aln": "--------------MDSQVEGKISPSQKESSSTSGLVSPSEDGPAHQKIHR----------------------------------DQLSVDQIKKIREE--RAQKRQVRRNSLISQGKDPDFPTPDLQFIERPFLPIN----------------------------------HDNSKGLTPATIQVTQDS----------LDVKIMTYNTLAQTLIRRDFFPE---SGPALKWHKRSKVLVHELKKYRPDVVSLQEVDYNELN-FWQENFHKLG--FDVIFKRHEG-KTHGLLVAWNNKKFQLDNDWMLDYDNILAGNVISARTRTKNIALIISLYFKGITDSSSRGIIVANTHLFWHPFGVFERLRQSYLVLQKIQEIKACSKYNGWHSLLMGDFNTEPEEPPYLAITKRPLILKGPIRAMVECSLAYRYSKKRNGEESDQDDEECDEKSRGEGHSDQPQNPKPESFTATKEEKALVNQLVALHNSLHVKGVSLYGIGYGKVHPENANGSHGEPGLSNWANTWCGLLDYIFYIEGDHNQDTRQKEPLNAFEGNNNVKIIGYLRMPCAQEMPKHSQPFEGEYASDHISLMCQIRLFFGGEKVHSLK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : . : : : .: ...:::** *:* *: . . * * * :::*: : .*::.***:: :. : * :* : * :..* : :. .:*.* . :: .*:.*. : : :*.***:::. : * :* :: . :: ****: * .. : .. . *: :. . :***: : :. : : . : . .*** .* : : ", "identical_positions": 40, "similar_positions": 91, "identity": "6.6%" }, { "cls_id": "homologset.agr.MGI:1196314", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99L04-1", "uniprot_id": "DHRS1_MOUSE", "id": "Q99L04-1", "name": "Dehydrogenase/reductase SDR family member 1", "aln": "MVAPMKGQVCVVTGASRGIGRGIALQLCKAGATVYITGRHLDTLRATAQEAQSLGGRCVPVVCDSSQESEVKSLFEQVDREQKGRLDVLVNNAYAGVQAILNTTNKSFWEVPASIWDDINNVGLRGHYLCSVYGARLMVPAGKGLIVIVSSPGGLQHMFNVPYGVGKAACDRLAADCAHELRRHGVSYVSLWPGLVQTEMVKEFMAKEDTPEDPLFKKMKPDFSSAESPEMSGKCVVALATDPNILNLSGKVLPSCDLARRYGLKDIDGRPVKDYFSLGYALSQVSSLGWLNSFLPGFLRVPKWVVTLYNSKF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6AXY8-1", "uniprot_id": "Q6AXY8_RAT", "id": "Q6AXY8-1", "name": "Dehydrogenase/reductase SDR family member 1", "aln": "MIMTMKGQVCVVTGASRGIGRGIALQLCQAGATVYITGRHLDTLRATAQEAQSLGGRCVPVVCDSSQESEVKSLFEQVDREQQGRLDVLVNNAYAGVQAILNTTTKSFWEAPASLWDDINNVGLRGHYLCSVYGARLMVPAGKGLIVVVSSPGGLQHMFNVPYGVGKAACDKLAADCAHELRRHGVSYVSLWPGLVQTEMVKEYVAKEEQPEDPLFKKMKSVLSSAETTEMSGKCVVALATDPNILSLSGKVLPSCDLARRYGLKDVDGRPVQDYFSLGYALSQVSSLRWLASYLPGFLRVPKWIVTLYTSKF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96LJ7-1", "uniprot_id": "DHRS1_HUMAN", "id": "Q96LJ7-1", "name": "Dehydrogenase/reductase SDR family member 1", "aln": "MAAPMNGQVCVVTGASRGIGRGIALQLCKAGATVYITGRHLDTLRVVAQEAQSLGGQCVPVVCDSSQESEVRSLFEQVDREQQGRLDVLVNNAYAGVQTILNTRNKAFWETPASMWDDINNVGLRGHYFCSVYGARLMVPAGQGLIVVISSPGSLQYMFNVPYGVGKAACDKLAADCAHELRRHGVSCVSLWPGIVQTELLKEHMAKEEVLQDPVLKQFKSAFSSAETTELSGKCVVALATDPNILSLSGKVLPSCDLARRYGLRDVDGRPVQDYLSLSSVLSHVSGLGWLASYLPSFLRVPKWIIALYTSKF", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* .*:**********************:****************..*********:**************:**********:***************:**** .*:***.***:*************:*************:****::****.**:**************:*************** ******:****::**.:***: :**::*::*. :****:.*:***************.*****************:*:*****:**:**. .**:**.* ** *:**.*******:::**.***", "identical_positions": 252, "similar_positions": 51, "identity": "80.51%" }, { "cls_id": "homologset.agr.MGI:1196316", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JZM0-1", "uniprot_id": "A0A0G2JZM0_RAT", "id": "A0A0G2JZM0-1", "name": "", "aln": "MQQEAER--------CRVRTKRPDMALYVPK-ARRGAALLKSGDQEENQGPPAFVLRE-QKEDCLPQK-TSTSKPESHRLSAGQSGRKDSNCREGKRSPPKLRKDRSPPKRNKEKACSKRGTGKPIDASSQEHQNSAHDAAAVSSIPLRRLFKPKEMECVEVQTSGGTGPWGVPPSQSSSEVSAAQVPNRPFQNVELCDFS-----GETFVNRNLESSIVTEAKVMELVSQFPQVVTTMLKPDGMAMPGTLSSDSETAPYGVETSHGMSKHSPGNISAISVPGEPDDAAHPTFVDFEAESES-TVNSTESVLGQNGVDSISETMGNVSLKMAIVSKLESTNGIIDPAVTGECG-NDSSADELCVKSEPSDTVDLVHEIDTGNGFRDVCDSASKAGMVDIAGTVC-DPVTVGSPCTAAVRESGESSGNMRNSSDYIEMSADVARLDSAKSETNSENSSSLNACSDIYAGSIASGFTASTGKLTESVPDCASSLPIKKTADSDITPCLDSELSMSNGSGILVESALASDLDTTEEMTEALHDLRTAEEFKTKEEDDSESRVCGIPFSD---SSVDTSVGLKTTDTSHTQGSIAVEESWESMFNDDGDCVDPRLLQE--------------LSGNMKNRKSIQEPRFDYYNHELPD---IDLSECEFPHVIEIYDFPQEFRTEDLLRIFCSYQKKGFDIKWVDDTHALGVFSSPIAARDALGIKHTMVKIRPLSQATRAAKAKAR-ACAEFLQPAKERPETSAALARRLVISALGVRSRQSKTEREAELRKLQEARERKRLEAKQREDIWEGRDQSVV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BJM3-1", "uniprot_id": "R3HCL_MOUSE", "id": "Q8BJM3-1", "name": "Coiled-coil domain-containing protein R3HCC1L", "aln": "MQQEAER--------CRVRTKRPDMALYVPK-ARRGTALLKSSDQEEGHGPPAFVPKD-QKEGCLPQK-ISASKPESQRRGAGHSDRKDVDCREGKRSASQLRKDRCPQKQNKEKACSKKGAEESTEASSQEHQHRAPDAGIVSSIPLQRLFKPKDMDCWEVQTAGATGHWRVSPSQSSSEVSAAQVPSRPFQNVELCDFS-----GETFVNRNLESSIVTEAKVPELVSQFPQVVTTLLKPDGMAMPVTLSSDSETAPSSLETPDGMSKHSPGDISVVSVPGGPDEDVDSTFVDFEVESEG-TVNSTESVLGQKGVDSILETVDNVSLKMAVVSKLESTNGTIDPAVTRECE-SDSSADELCVKSEPSDTAVLVHEIDTDDGFRNVCDSTSKACMVDIAGTAC-DPVTEGSSCTGAVGESGESSGNMRNFSDYIEMSADVAPLDRAKSENDSENISSLSACSDIYAESIASGFTESTGKLIESVSDGASSLPIKKTADSNIATCLDSELSMSDASDVLLESALGSDLDTTEEMTEALHDLKTAEEFKTKEEDYSESVVCGISFSD---SSVETSVDLKTTDTSHIQGSSAVEESWESMFNDDGDCVDPRLLLE--------------LSGNVKNRKSIQEPRFDYYSHELPD---IDLSECEFPHVIEIYDFPQEFRTEDLLRIFCSYQKKGFDIKWVDDTHALGVFASPITARDALGTKHTMVKIRPLSQATRAAKAKAR-ACAEFLQPAKERPETSAALARRLVISALGVRSKQSKTEREAELRKLQEARERKRLEAKQREDIWEGRDQSVV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7Z5L2-1", "uniprot_id": "R3HCL_HUMAN", "id": "Q7Z5L2-1", "name": "Coiled-coil domain-containing protein R3HCC1L", "aln": "MQQESER--------CRVRARRPDMALYVPK-ARRGAVLLKTGDEEESCGSPNSVVKEKQKESSLSQKEVFKDKPEARRLNIN-PDRKEHNCREEKKSSTKLRMDTCLQKTN--RVCSKRGTTESKEVLSQGQQQGAPNAGVITNAPLQRHFKPKKVECLEVETTDVTGHERILLSQACLEISEAQVPSKPFQNVEFCDFSRHEPDGEAFEDKDLEGRIETDTKVLEILYEFPRVFSSVMKPENMIVPIKLSSDSEIVQQSMQTSDGILNPSSGGITTTSVPGSPDGVFDQTCVDFEVESVGGIANSTGFILDQKDTDSIPATMGHISLS-------ESTNDTVSPVMIRECEKNDSTADELHVKHEPPDTAVLAHETHRDSGFKNVGDITNKACMMDTTGMSCSDHVTVDSPYVVAVRIADETSINTRSFSKFVGMSADATPLHVARSGNDTEDFSNPSACSDIYGESISSHFTESTGKLIESLSDCASSLPIKKIAGSNYNTFLDSELSMLNGTKVLSDSAVGIDLGSTGDTTEALHELRTAEEFKTEEQDDSGSIEFGVSFPDRESSSMETSIEPKATETSHTEGITAIEESWESMFNDDGDCLDPRLLQEGILMHIKPENHCSKLSGNTKSRESIQEPRSDYYNHEVPD---IDLSDCEFPHVIEIYDFPQEFHTEDLLRVFCSYQKKGFDIKWVDDTHALGVFSSPITARDALGIKHTMVKIRPLSQATRAAKAKAR-AYAEFLQPAKERPETSAALARRLVISALGVRSKQSKTEREAELKKLQEARERKRLEAKQREDIWEGRDQSTV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F1G4-1", "uniprot_id": "E7F1G4_DANRE", "id": "E7F1G4-1", "name": "", "aln": "METEAAQPEQGSKTAVPARTKRPTMEVYVPK-KRQ-------------------------AEK--------TDKPQSDG---------------DKKSKPRPR-------------------------YTDKARKNKKDKAKVS----------------------------------------------------------------------------------------------------------------------ETQNGEIKPDAG----------------------EQGGGG-----------------------------------DTENQNTEP-------------------------------------------------------------------------------------------------------EKDEE----------------------STG-----------------------------------------------DMNTTSRTVHSPEDSSSVLEHDDEEMKDE-------------------------------------EENWDSLFNDDGDCLDPHLMEEMS------------LKEGRK-KQSAQDSGFDYYNWSPQDDEEVELRDDELSHIIEIYDFPTEFKTEDLVRSFSSFQQKGFDITWIDDTHALGLFSSPIAARDALRMKNPMMKVRPLSSSSNATKAKAR-SCSDYLLPAKERPQTSAALARRLVIGALGVKSNQTREEREAERNKLQQAREQKRLAAKQREDAWEGK-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E1JIB4-1", "uniprot_id": "E1JIB4_DROME", "id": "E1JIB4-1", "name": "R3H domain-containing protein", "aln": "MDQEFVH------------NVGCDIELFVKKRLNRGVLLFPPVGNYRRYLIHQTCEKYRQQYDLFTFS--VGQGPQRRTVLCFRNQLLDPSGFENRKQQQQREKDREREAAR---------SWRSNNNSHYHTNGRSSSASRRSATELCKMGVKKHISETPLSKSNSVDLYRPPALRNNSNNNNSS------------------------------------------------------SEEAAAVNEAITTPLAAGTATTASTSPTSKESPNREADASAAAAAAATRRERRPDRAVYVPR-----------------------------------ARRSQTTPPTTTTTTT--AAAATAVATTSPPAAAAVVAATITTAPDSPPVADTQPSKADDVNGQPPS------KSKKSKSHRERRERAKKTTTATTADNATVLVISASENDTQSNEEHRPAKPADCDKEIMSGAQRTKPGNGNKSASNGKSQASPPLR-IEDVVAARSTNGEEPAKCDNDVRELQRASKEINRSNRRIMKQTFNSDVLEIPEKIETSATKAIPTSPQAS--------ATAKPPVDSTTEDDDEEDEDDWEKMFDESGDCLDPKLLQELT---------------ESVGKCKIELPKMDYTVFHIKQ---QLLNEEEFPHVLEVSNFPVEFKTPDLLMLFAQYRGSGFDIKWVDDTHALAVFSSSRIAAEVLTMGHPFVKLKPLAEATLESRLKAKKAGAVSMQPYRQRPETCTALARRLVSGALGVKLPTAPQERENERRVLREAKERKLLAAKQRDEVWES------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: * : : ::* * .: . *: ::. : . . . . : : : ... . * .: * ..* ::. : . * : *:.*:.:*::.***:**:*: * : . : . ** : * : *:.*::*: :** **:* **: *..:: .****.*:******.:*:*. * :.* :.::*::**:.:: :: **: : : : * ::**:*.:******* .****: : *** * . *::*:*:* * ****:: **. ", "identical_positions": 83, "similar_positions": 104, "identity": "10.18%" }, { "cls_id": "homologset.agr.MGI:1196325", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A0Z1-1", "uniprot_id": "D4A0Z1_RAT", "id": "D4A0Z1-1", "name": "Tetraspanin", "aln": "----MHYYRYSNAEVSCWYKYLLFSYNIVFWLAGVVFLGVGLWAWSEKGVLSDLTKVTRLHGIDPVVLVLMVGVVMFTLGFAGCVGALRENICLLKFFCGAIVLIFFLELAVAVLAFLFQD--WVRDRFREFFESNIRSYRDDIDLQNLIDSLQKAN-QCCGAYGPEDWDLNVYFNCSG-ASYSREKCGVPFSCCVPDPAQKVVNTQCGYDVR---------------IQLKSKWDEF-----------------------IFTKGCIQALEGWLPRNIYIVAGVFIAISLLQIFGIFLARTLISDIEAVKAGHHF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8QZY6-1", "uniprot_id": "TSN14_MOUSE", "id": "Q8QZY6-1", "name": "Tetraspanin-14", "aln": "----MHYYRYSNAEVSCWYKYLLFSYNIVFWLAGVVFLGVGLWAWSEKGVLSDLTKVTRLHGIDPVVLVLMVGVVMFTLGFAGCVGALRENICLLKFFCGAIVLIFFLELAVAVLAFLFQD--WVRDRFREFFESNIKSYRDDIDLQNLIDSLQKAN-QCCGAYGPEDWDLNVYFNCSG-ASYSREKCGVPFSCCVPDPAQKVVNTQCGYDVR---------------IQLKSKWDEF-----------------------IFTKGCIQALEGWLPRNIYIVAGVFIAISLLQIFGIFLARTLISDIEAVKAGHHF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NG11-1", "uniprot_id": "TSN14_HUMAN", "id": "Q8NG11-1", "name": "Tetraspanin-14", "aln": "----MHYYRYSNAKVSCWYKYLLFSYNIIFWLAGVVFLGVGLWAWSEKGVLSDLTKVTRMHGIDPVVLVLMVGVVMFTLGFAGCVGALRENICLLNFFCGTIVLIFFLELAVAVLAFLFQD--WVRDRFREFFESNIKSYRDDIDLQNLIDSLQKAN-QCCGAYGPEDWDLNVYFNCSG-ASYSREKCGVPFSCCVPDPAQKVVNTQCGYDVR---------------IQLKSKWDES-----------------------IFTKGCIQALESWLPRNIYIVAGVFIAISLLQIFGIFLARTLISDIEAVKAGHHF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58H262-1", "uniprot_id": "A0AC58H262_DANRE", "id": "A0AC58H262-1", "name": "Tetraspanin", "aln": "MNKKMHYYRYENAEVSCCYKYLMFSYNIIFWLAGSAFIAIGFWAWSEKGVLSDLTQVTRLHGFDPVWGVLVVGTVTFILGFAGCVGALRENICLLKFFSGVIGFIFFLELTAAVLAFVFQG--QVREWISEFFLANVKAYRDDIDLQNLIDSLQKLN-HCCGAKHPNDWNMNVYFNCSNKNNLSREKCGVPFSCCISDPAVTVLNTQCGYDVRE--------------KGTLNDWSSS-----------------------IYIKGCIDALEDWLPRNLYIVAGVFIVISLLQMVGIFLARTLIGDIEKVKFNYY-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VMJ6-1", "uniprot_id": "Q9VMJ6_DROME", "id": "Q9VMJ6-1", "name": "", "aln": "MPAAVRKFRRETSEISCCLKYLLFASNVILWLSALLVLSVGIWAWSEKGMFRNIARLH-FIALDPAFVLIILGGVTFLLGFMGSVGALRENTCLLGAYAIFLSVLLIAEIGFCAVAFVLKDKGWIKDQATEGLKAFIRHYREDADQQNLIDWIQEDWLQCCGIDGPKDWDSNNYFNCSSIAIGSREACGVPFSCCRRRPQEVIKNKQCGYDVRKEGYPVDRNIHERGCLRAGEDWLEAHLISVAIGCVALLVLQGMELSKIIYEKGCVQAGEEWMEHNLIIISATVIVVMFFQILGICFAQNLRADIYTQKSKWH-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: :* ..:::** ***:*: *:::**:. .:.:*:*******:: ::::: : .:**. ::::* * * *** *.******* *** :. : .::: *: ..:**:::. ::: * : : :: **:* * ***** :*: :*** *:**: * *****. *** ******** * : *.******* ..* . *: ***::* * *: :*: *::...*.: ::*:.** :*:.* .** * : ", "identical_positions": 102, "similar_positions": 92, "identity": "32.28%" }, { "cls_id": "homologset.agr.MGI:1196326", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P61601-1", "uniprot_id": "NCALD_HUMAN", "id": "P61601-1", "name": "Neurocalcin-delta", "aln": "MGKQNSKLRPEVMQDLLESTDFTEHEIQEWYKGFLRDCPSGHLSMEEFKKIYGNFFPYGDASKFAEHVFRTFDANGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISKAEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNRDGKLSLEEFIRGAKSDPSIVRLLQCDPSSAGQF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5PQN0-1", "uniprot_id": "NCALD_RAT", "id": "Q5PQN0-1", "name": "Neurocalcin-delta", "aln": "MGKQNSKLRPEVMQDLLESTDFTEHEIQEWYKGFLRDCPSGHLSMEEFKKIYGNFFPYGDASKFAEHVFRTFDANGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISKAEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNRDGKLSLEEFIRGAKSDPSIVRLLQCDPSSAGQF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91X97-1", "uniprot_id": "NCALD_MOUSE", "id": "Q91X97-1", "name": "Neurocalcin-delta", "aln": "MGKQNSKLRPEVMQDLLESTDFTEHEIQEWYKGFLRDCPSGHLSMEEFKKIYGNFFPYGDASKFAEHVFRTFDANGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISKAEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNRDGKLSLEEFIRGAKSDPSIVRLLQCDPSSAGQF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A9JTH1-1", "uniprot_id": "NCLDA_DANRE", "id": "A9JTH1-1", "name": "Neurocalcin-delta A", "aln": "MGKQNSKLRPEVMQDLLESTDFTEHEIQEWYKGFLRDCPSGNLSMEEFKKIYGNFFPYGDASKFAEHVFRTFDANGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISKSEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNRDGKLSLEEFIKGAKTDPSIVRLLQCDPSSAGQF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6AXL4-1", "uniprot_id": "NCLDB_DANRE", "id": "Q6AXL4-1", "name": "Neurocalcin-delta B", "aln": "MGKQNSKLRPEVIQDLLDNTDFTEHEILEWYKGFLRDCPSGALSMDEFKKIYGNFFPYGDASKFAEHVFRTFDANGDGTIDFREFIIALSVTSRGRLDQKLKWAFSMYDLDGNGYISKAEMLEIVQAIYKMVSSVMKMPEDESTPEKRTDKIFRQMDTNRDGKLSLEEFVEGAKNDPSIVRLLQCDPSSAGQ-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P42325-1", "uniprot_id": "NCAH_DROME", "id": "P42325-1", "name": "Neurocalcin homolog", "aln": "MGKQNSKLKPEVLEDLKQNTEFTDAEIQEWYKGFLKDCPSGHLSVEEFKKIYGNFFPYGDASKFAEHVFRTFDANGDGTIDFREFLCALSVTSRGKLEQKLKWAFSMYDLDGNGYISRQEMLEIVTAIYKMVGSVMKMPEDESTPEKRTDKIFRQMDRNKDGKLSLEEFIEGAKSDPSIVRLLQCDPQSH---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06389-1", "uniprot_id": "NCS1_YEAST", "id": "Q06389-1", "name": "Calcium-binding protein NCS-1", "aln": "MGAKTSKLSKDDLTCLKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKVDPSIIGALNLYDGLI---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** :.*** : : * :.* * ** :*:****:***** *: ::* *** :***:*....**:*:* .** :.:* *.*.**: .**.**** *::**.***.:***: :***: *** ** ::***:.*::.: ***:*** *..***: ** *.** ::*:** .*:* ****: *: ", "identical_positions": 92, "similar_positions": 57, "identity": "47.67%" }, { "cls_id": "homologset.agr.MGI:1196332", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AAE4-1", "uniprot_id": "A0A8I6AAE4_RAT", "id": "A0A8I6AAE4-1", "name": "", "aln": "---------------------------------------------MSAQSLLHSVFSCSSPASGGTASTKGFSKRKLRQTRSLDPALISGCGS-EMGAED-------------GLRGSTVSRLNSPQLSAESLGSRLASSPRSQHLRATRFPAPRPLCSSFSTPSTPQEKSPSGSFHFDYEVPLSRSGLKKSMAWDLPSVLTG--SVSGRNPASILGSSGGGPNG------IFASPRRWLQQRKFQPPPNSRSHPYVVWRSEGDFTWNSMSGRSVRLRSVPIQSLSELERARLQEVAFYQLQQDCDLGCQITIPK-------DGQKRKKSLRKKLDSLGKEKNKDKEFIP-QAFGMPLSQVIAN-DRAYKLKQDLQREEQKDAS-DFVSSLLPF--------GNKKQNKELSSSNSSLSSTSETPNESTSPNTPEPAPRARRRGAMSVDSITDLDDNQSRLLEALQLSLPAEAQNKKQKAR-DKKLSLNPIYR------QVPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRG----VDVCLEEEHSVHDVAALLKEFLRDMPDPLLTRELYT---------------------------AFINTLLLEPEEQLGTLQLLIYLLPPCN----------CDTLHRLLQFLSIVARHAEDNVSKDG----------------------------------------------QEVTGNKMTSLNLATIFGPNLLHKQK----------------------SSDKEYSVQSSARAEESTAIIAVVQKMIENYEALFMVPPDLQNEVLISLLETDPDVVDYLLRRKASQSSSPDMLQSEVSFSMGGRHSSTDSNKASSGDISPYDNNSPVLSERSLLAMQEDRARGGSEKLYKVPEHYTLLDHLPSPKSKSRESSPGPRLGKDMSEEPFNIWGTWHSTLKSGSKDPGMTGSYGDIFESSSLRPRLCSLSQG--------------------------NLSLNWPRCQGSTTGMDSGTQVIRRTQTAATVEQCNVHLPVSRVCSTPHIQDGGRGSRRPAARSEPFLSL--------------NSTEDLAEGKEDVAWLQSQAQAVYQRPQESGRDDRRPPPPYPGSGKPATTSAQQPLEPPLWRLQRQEEGSETVVEE-----------GGQQASGEHQTRPKKLSSAYSLSASEQDKQNLGEASWLDWQRERWQIWELLSTDNPDALPETLV--------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O54834-1", "uniprot_id": "RHG06_MOUSE", "id": "O54834-1", "name": "Rho GTPase-activating protein 6", "aln": "---------------------------------------------MSAQSLLHSVFSCSSPASGGTASAKGFSKRKLRQTRSLDPALIGGCGS-EMGAEG-------------GLRGSTVSRLHSPQLLAEGLGSRLASSPRSQHLRATRFQTPRPLCSSFSTPSTPQEKSPSGSFHFDYEVPLSRSGLKKSMAWDLPSVLAGSGSASSRSPASILSSSGGGPNG------IFSSPRRWLQQRKFQPPPNSRSHPYVVWRSEGDFTWNSMSGRSVRLRSVPIQSLSELERARLQEVAFYQLQQDCDLGCQITIPK-------DGQKRKKSLRKKLDSLGKEKNKDKEFIP-QAFGMPLSQVIAN-DRAYKLKQDLQREEQKDASSDFVSSLLPF--------GNKKQNKELSSSNSSLSSTSETPNESTSPNTPEPAPRARRRGAMSVDSITDLDDNQSRLLEALQLSLPAEAQSKKEKAR-DKKLSLNPIYR------QVPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRG----VDVCLEEEHSVHDVAALLKEFLRDMPDPLLTRELYT---------------------------AFINTLLLEPEEQLGTLQLLIYLLPPCN----------CDTLHRLLQFLSIVARHADDNVSKDG----------------------------------------------QEVTGNKMTSLNLATIFGPNLLHKQK----------------------SSDKEYSVQSSARAEESTAIIAVVQKMIENYEALFMVPPDLQNEVLISLLETDPDVVDYLLRRKASQSSSPDILQTEVSFSMGGRHSSTDSNKASSGDISPYDNNSPVLSERSLLAMQEDRARGGSEKLYKVPEQYTLVGHLSSPKSKSRESSPGPRLGKEMSEEPFNIWGTWHSTLKSGSKDPGMTGSYGDIFESSSLRPRPCSLSQG--------------------------NLSLNWPRCQGSPTGLDSGTQVIRRTQTAATVEQCSVHLPVSRVCSTPHIQDGSRGTRRPAASSDPFLSL--------------NSTEDLAEGKEDVAWLQSQARPVYQRPQESGKDDRRPPPPYPGSGKPATTSAQLPLEPPLWRLQRHEEGSETAVE------------GGQQASGEHQTRPKKLSSAYSLSASEQDKQNLGEASWLDWQRERWQIWELLSTDNPDALPETLV--------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43182-1", "uniprot_id": "RHG06_HUMAN", "id": "O43182-1", "name": "Rho GTPase-activating protein 6", "aln": "---------------------------------------------MSAQSLLHSVFSCSSPASSSAASAKGFSKRKLRQTRSLDPALIGGCGSDEAGAEG-------------SARGATAGRLYSPSLPAESLGPRLASSSRGPPPRATRLPPPGPLCSSFSTPSTPQEKSPSGSFHFDYEVPLGRGGLKKSMAWDLPSVLAG--PASSRSASSILCSSGGGPNG------IFASPRRWLQQRKFQSPPDSRGHPYVVWKSEGDFTWNSMSGRSVRLRSVPIQSLSELERARLQEVAFYQLQQDCDLSCQITIPK-------DGQKRKKSLRKKLDSLGKEKNKDKEFIP-QAFGMPLSQVIAN-DRAYKLKQDLQRDEQKDAS-DFVASLLPF--------GNKRQNKELSSSNSSLSSTSETPNESTSPNTPEPAPRARRRGAMSVDSITDLDDNQSRLLEALQLSLPAEAQSKKEKAR-DKKLSLNPIYR------QVPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRG----IDVSLEEEHSVHDVAALLKEFLRDMPDPLLTRELYT---------------------------AFINTLLLEPEEQLGTLQLLIYLLPPCN----------CDTLHRLLQFLSIVARHADDNISKDG----------------------------------------------QEVTGNKMTSLNLATIFGPNLLHKQK----------------------SSDKEFSVQSSARAEESTAIIAVVQKMIENYEALFMVPPDLQNEVLISLLETDPDVVDYLLRRKASQSSSPDMLQSEVSFSVGGRHSSTDSNKASSGDISPYDNNSPVLSERSLLAMQEDAAPGGSEKLYRVPGQFMLVGHLSS--SKSRESSPGPRLGKDLSEEPFDIWGTWHSTLKSGSKDPGMTGSSGDIFESSSLRAGPCSLSQG--------------------------NLSPNWPRWQGSPAELDSDTQGARRTQAAAPATEGRAHPAVSRACSTPHVQVAGKAER-PTARSEQYLTL--------------SGAHDLSESELDVAGLQSRATPQCQRPHGSGRDDKRPPPPYPGPGKPAAAAAWIQGPP---------EGVETPTDQ-----------GGQAAEREQQVTQKKLSSANSLPAGEQDSPRLGDAGWLDWQRERWQIWELLSTDNPDALPETLV--------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TYH8-1", "uniprot_id": "A0AB32TYH8_DANRE", "id": "A0AB32TYH8-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVLFYMG----SDKTSSVVMQ-------------------------------PEDPVRQDMQFYYVGDHTWATMLGQSVRLQPVAIQSLSELERARLQEVALYHLER-RDLDFKISIPR-------EIRKRRKSLRRKFDSFSKEK-KDRESAP-KAFSIPLSQVIAN-DLAYKQRQDALKESRRDCL-DLEASVLHFRAEKWQQNGNRPLGKTVLSPGAASSPVLELHSKPPSSAFMDNTSRTHRRGGMSVDSISDMVESQSRLLEALQLSHPNELEMKKAAGRTQAKLSLNPIYR------QVPRVVERCCNHIQTYGLQTLGIFRVGSSKKRVRQLREDFDNG----IDVVLDEEHSVHDVAALLKEFLRDMPDPLLPRELYR---------------------------AFLHANLLRGADQLSYLQQLLYLLPPCN----------CDTLLRLLTLLHTVQENANSSTGPNK----------------------------------------------QEISGNKMTAANLAVIFGPNLLQKER----------------------GSERELSPQALG-IEDSTAVISVTLMLIQNHQHLFMVSAELQQEVLMSLIQTDPDVIDYLLRRKLSSSSS--LTVEPDSGGRRDTQSSLDSMGQSSDDLSSREPLCPLYPEHSAIGSLS------SEVLLNV-------LHLNTNRKRSSEVPP-----------------------KS-------------IVKMRQFHSHHNLLSLT--------------------------QSSSNAP-------SDERELQEQRQASSRHTCPEERLHFTLSRKDSGSQPQ----------------------------------------SPREKGIWVRQNSNASSTTS-----DDSKTPSNFWDFFTGKVS------------------GSETIIP----------------------VVRRSPSLQNFFNDHSQSEKR-----------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "H9XVN1-1", "uniprot_id": "H9XVN1_DROME", "id": "H9XVN1-1", "name": "", "aln": "MEFPKENEESVNCLRSPMAAVKKRSGPLDIALDEANDVSKIWSLPLGNASSMRKPMIFASEHSEGVASPNKVRRRSTKDKEKKRERWLLTRKTWRYMTDAGRKLIPDGYQTGSGNHDLIEDQFQRVCLSEPSFILWSRRTSYPGAFSCSKRRLKPLLRHASASRRKQTVDATKDYHIADRVIELLQTYLKLRDAYKTTTLLGTKTVRPDQTSSPSAQRPNFKNNGDNHQVISSGTSIQTELLSLLKLLSNCPLFTHEGIQLKFGDAPLSILEDKVLLKKIYSALKKQQLHRTLHSKDPYQANFSTSLSCLIKNGKELSRGNTDSNRSNKLLHDNFFCLMKCDTKPIIPSPKTEFFLDLNKVPQNFELKNKLNSNGQSVERIQKTCGTQTNFIQLS-------ELKTLAEQYNLMVTNCDNTLKLLEEPSKQDCSKSSHLIFRRSSLDEDISQSVSDTIKRYLNMARKKSMQDSDSNRFKSINYDKNLRNIKAKGVLNPPGISAGLHKAVQTLNAWPLIALDFIRGNESSLNLKNAHLEWLRLEDERSHMQLERDKNPIELRSKVNPLQIASPANTSSYSKCTSAPTSPTSHSKLEKAIRTSSGLLSSSSQFISNILHGHNNAGNQFNTLTDKLPDCNQSHATASMQKSKSLSNVGQFVAKRMWRSRSKSQNKRSYLKSSIPTLKWYPSEHFLWISESGESFQIVETNLTRLSKIESDIVKNFALEKIQELNIGNIEDLKISPQKRRCVPKKKSLTTSFFDNGKKDDQNPRSVLFGTSLECCLERDSKRNVTMEDRSKYSLLSMFRGSGSTPGSVLKLNDNVRSCESLPSKSLEYGSTELSAYVRGSFSNISKPLASLSQSENEDTELNFVKAYQEHSQLMVPIFVNNCIDYLEDNGLQQVGLFRVSTSKKRVKQLREEFDKDIYFGISVDTCPHDVATLLKEFLRDLPEPLLCNTLYLTFLKTQRIRNRRLQLEAISHLIRLLPIPHRDTLYVLLVFLAKVAAHSDDIWSTEGCCLTLGNKMDSYNLATVFAPNILRSTHLTFSRDKEQENMIDAINVVRTMINHYEEIFNISAELLNVIYTQALEACPEKLYELISTKVYGTEWTQQQIDDPQPGSLSDVLLEPPIHGKRYENINDFNNINFKRCQDKRRDHSDPDKKKNNNENLEIITASLKISVAEQSHISLKEPIKEQEPITSYKQFSRSTLPTSISDVGVNTLRTDGAKLENKMKILTSNINKQDIPIKTTYKRQNLISSSRRISQEP", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . ..:..: .: . : :: .* *: : .: : *:. *: : .*. *. : : .: .* *: :: .: * . * * * : *.:* * : * ..: .: : . :..: : : : : . . : .:... . : **..:. * .: :. .* *: : . : : :: . * * : :. :. . : :: * ::.::* ..*. .::: : :: . .: *:.::. :: : :: : * . . *: * : . :: * ** ** ..:* .: :: .: .. . ::.: :*: *:. * . :: ::: .. : : : *. .::. * *. . . : :: : : * :. . .*: * . . : * ... .: . .: . . * :. :.: :: *. * : : . : . * ..** . : . . : . .* . . . :. . . : .* . ", "identical_positions": 54, "similar_positions": 222, "identity": "4.28%" }, { "cls_id": "homologset.agr.MGI:1196334", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z2Q3-1", "uniprot_id": "HYAL2_RAT", "id": "Q9Z2Q3-1", "name": "Hyaluronidase-2", "aln": "------------------------------MRAGLGPIITLALVLEVAWASELKPTAPPIFTGRPFVVAWNVPTQECAPRHKVPLDLRAFDVEATPNEGFFNQNITTFYYDRLGLYPRFDAAGMSVHGGVPQNGSLCAHLPMLKEAVERYIQTQEPAGLAVIDWEEWRPVWVRNWQEKDVYRQSSRQLVASRHPDWPSDRIVKQAQYEFEFAARQFMLNTLRYVKAVRPQHLWGFYLFPDCYNHDYVQNWDSYTGRCPDVEVAQNDQLAWLWAENTALFPSVYLDKTLASSKHSRNFVSFRVQEALRVAHTHHANHALPVYVFTRPTYTR--------RLTELNQMDLISTIGESAALGSAGVIFWGDSVYASSMENCQNLKKYLTQTLVPYIVNVSWATQYCSWTQCHGHGRCVRRNPSASTFLHLSPSSFRLVPGRTPSEPQLRPEGELSEDDLSYLQMHFRCHCYLGWGGEQCQWNHKRAAGDASRAWAGAHLASLLGLVAMTLTWTL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35632-1", "uniprot_id": "HYAL2_MOUSE", "id": "O35632-1", "name": "Hyaluronidase-2", "aln": "------------------------------MRAGLGPIITLALVLEVAWAGELKPTAPPIFTGRPFVVAWNVPTQECAPRHKVPLDLRAFDVKATPNEGFFNQNITTFYYDRLGLYPRFDAAGTSVHGGVPQNGSLCAHLPMLKESVERYIQTQEPGGLAVIDWEEWRPVWVRNWQEKDVYRQSSRQLVASRHPDWPSDRVMKQAQYEFEFAARQFMLNTLRYVKAVRPQHLWGFYLFPDCYNHDYVQNWESYTGRCPDVEVARNDQLAWLWAESTALFPSVYLDETLASSVHSRNFVSFRVREALRVAHTHHANHALPVYVFTRPTYTR--------GLTGLSQVDLISTIGESAALGSAGVIFWGDSEDASSMETCQYLKNYLTQLLVPYIVNVSWATQYCSWTQCHGHGRCVRRNPSANTFLHLNASSFRLVPGHTPSEPQLRPEGQLSEADLNYLQKHFRCQCYLGWGGEQCQRNYKGAAGNASRAWAGSHLTSLLGLVAVALTWTL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q12891-1", "uniprot_id": "HYAL2_HUMAN", "id": "Q12891-1", "name": "Hyaluronidase-2", "aln": "------------------------------MRAGPGPTVTLALVLAVSWAMELKPTAPPIFTGRPFVVAWDVPTQDCGPRLKVPLDLNAFDVQASPNEGFVNQNITIFYRDRLGLYPRFDSAGRSVHGGVPQNVSLWAHRKMLQKRVEHYIRTQESAGLAVIDWEDWRPVWVRNWQDKDVYRRLSRQLVASRHPDWPPDRIVKQAQYEFEFAAQQFMLETLRYVKAVRPRHLWGFYLFPDCYNHDYVQNWESYTGRCPDVEVARNDQLAWLWAESTALFPSVYLDETLASSRHGRNFVSFRVQEALRVARTHHANHALPVYVFTRPTYSR--------RLTGLSEMDLISTIGESAALGAAGVILWGDAGYTTSTETCQYLKDYLTRLLVPYVVNVSWATQYCSRAQCHGHGRCVRRNPSASTFLHLSTNSFRLVPGHAPGEPQLRPVGELSWADIDHLQTHFRCQCYLGWSGEQCQWDHRQAAGGASEAWAGSHLTSLLALAALAFTWTL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7TES9-1", "uniprot_id": "A0A8N7TES9_DANRE", "id": "A0A8N7TES9-1", "name": "Hyaluronidase", "aln": "MSERTGVLNGFSQIRSEMKNITHLSGTTRTQRASWLQVLLLMLFWTCLKAQQLKNTRWPLYSGKPLLLAWNAPTEDCRPRHDVTFQLDQFQIVASPNEGFTKQNLTIFYQDRLGLYPYFKPDSTPVYGGLPQAASLTQHLEKMPDGLKKYIKDQAVKGLAVIDWEEWRPLWIRNWGPKLIYRDRSQRLVAEKNPTWPLDQVTKVAQQEFELSARKFMLETLRLAKSLRPQQLWGYYLFPDCYNHNYQTNLQNYTGQCPDIEVSRNNELKWLWTESTALYPSVYMGKILKDNPKGRQFVRNRVKEGMRLASVGDG-SARPVFVYTRPTYLTNMTSSNPAELLLLTEMDLVSTIGESVALGVAGVILWGDSTYASSQATCSSLNEYLRGPLGRYLLNVTSAAEQCSRNLCGFRGRCLRKQPNTDTYLHLSASTHRIER----QANTLKLTGQMSEEELGRLRDDFQCQCYNGYSGDDCSIKD-NGNRAAALWTSALQYWVLPLILMGFLH---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M3ATS4-1", "uniprot_id": "A0A8M3ATS4_DANRE", "id": "A0A8M3ATS4-1", "name": "Hyaluronidase", "aln": "MSK---------PLSWRTKVMAHWI------RLYWRICLLVHLTL----AEDLKPTRWPLYPQKPLVLVWNAPTEDCRPRHKVHFQLDQFQIVASPNQGFTKQNLTIFYKDRLGLYPHY-EDGTAVNGGLPQIASLTQHLEKMPEGIEKYIRDPLAKGLAVIDWEEWRPLWIRNWEAKEIYKRQSKHLVSQKNPDWTSSQISKTAQMEFELSSRKFMQETLRLAKSLRPHQLWGFYLFPDCYNHDYRNSLESYTGRCPDVELVRNDLLKWLWTESTALFPSIYMGSVLRSTSFGRQFVRNRVKEGMRLASVGEG-LARPVFVYSRPTYAN--------ELEVLTETDLVSTIGESVALGAAGIVLWGDAAYASSNASCSSINQYLRGPLGQYLLNVSTAAEQCSGFLCSSHGRCLRRHADTDTYLHLDPKTHTIVG----QGSEMRVRGDLSVEEHRRMTKDFQCQCFSGYQGERCDLEDPLQQRGHGNTLKALWIYPLSPLLLHLLT---", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : : * * :** * *::. :*:::.*:.**::* ** .* ::* *:: *:**:** :**:* ** ******* : . .* **:** ** * : . :::**: ********:***:*:*** * :*: *::**:.::* *. .:: * ** ***:::::** :*** .*::**::***:*********:* . :.***:***:*: :*: * ***:*.***:**:*:.. * .. .*:** **:*.:*:* . .. * **:*::**** * *.: **:******.*** **:::***: ::* .*. ::.** * *::**: *:: ** * :***:*::..:.*:***...:. : :: *::* : : .*:*:*: *: *: *. . . . * : : ", "identical_positions": 176, "similar_positions": 144, "identity": "34.44%" }, { "cls_id": "homologset.agr.MGI:1196337", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5PSV4-1", "uniprot_id": "BRM1L_HUMAN", "id": "Q5PSV4-1", "name": "Breast cancer metastasis-suppressor 1-like protein", "aln": "MPVHSRGDKKETNHHDEMEVDYAENEGSSSEDEDTESSSVSEDGDSSEMDDEDCERRRMECLDEMSNLEKQFTDLKDQLYKERLSQVDAKLQEVIAGKAPEYLEPLATLQENMQIRTKVAGIYRELCLESVKNKYECEIQASRQHCESEKLLLYDTVQSELEEKIRRLEEDRHSIDITSELWNDELQSRK-KRKDPFSPDKKK-PVVVSGPYIVYMLQDLDILEDWTTIRKAMATLGPHRVKTEPPVKLEKHLHSARSEEGRLYYDGEWYIRGQTICIDKKDECPTSAVITTINHDEVWFKRPDGSKSKLYISQLQKGKYSIKHS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3Z9D3-1", "uniprot_id": "D3Z9D3_RAT", "id": "D3Z9D3-1", "name": "", "aln": "MPVHSRGDKKETNHHDEMEVDYAENEGSSSEDEDTESSSVSEDGDSSEMDDEDCERRRMECLDEMSNLEKQFTDLKDQLYKERLSQVDAKLQEVIAGKAPEYLEPLATLQENMQIRTKVAGIYRELCLESVKNKYECEIQASRQHCESEKLLLYDTVQSELEEKIRRLEEDRHSIDITSELWNDELQSRK-KRKDPFSPDKKK-PVVVSGPYIVYMLQDLDILEDWTTIRKAMATLGPHRVKTEPPVKLEKHLHSARSEEGRLYYDGEWYIRGQTICIDKKDECPTSAVITTINHDEVWFKRPDGSKSKLYISQLQKGKYSIKHS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3U1T3-1", "uniprot_id": "BRM1L_MOUSE", "id": "Q3U1T3-1", "name": "Breast cancer metastasis-suppressor 1-like protein", "aln": "MPVHSRGDKKETNHHDEMEVDYAENEGSSSEDEDTESSSVSEDGDSSEMDDEDCERRRMECLDEMSNLEKQFTDLKDQLYKERLSQVDAKLQEVIAGKAPEYLEPLATLQENMQIRTKVAGIYRELCLESVKNKYECEIQASRQHCESEKLLLYDTVQSELEEKIRRLEEDRHSIDITSELWNDELQSRK-KRKDPFSPDKKK-PVVVSGPYIVYMLQDLDILEDWTTIRKAMATLGPHRVKTEPPVKLEKHLHSARSEEGRLYYDGEWYIRGQTICIDRKDECPTSAVITTINHDEVWFKRPDGSKSKLYISQLQKGKYSIKHS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4V8V1-1", "uniprot_id": "BM1LA_DANRE", "id": "Q4V8V1-1", "name": "Breast cancer metastasis-suppressor 1-like protein-A", "aln": "MPVHSR-EKKESN-HEEMEVDFAEQEGSSSEDEDTESSSVSEDGESSEMDDEDCERRRMECIDEMTNLEKQFTDLKDQLYKERLNQVDAKLQEVMSGKAAEYLEPLATLQENMQIRTKVAGIYRELCLESVKNKYDCETQAAFQHWESEKLLLFDTVQTELEEKIRRLEEDRHSIDITSELWNDELQSRKNKKKDPFSPDKKKKPVVVSGPYIVYMLQDLDILEDWTAIRKAMATLGPHRVKTDASSKIDKLQHNARSEDGRLFYDGEWYSRGQAITIDKKDEYPTSAVITTINHDEVWFKRVDGSKSKLYVSQLQKGKYTVKHA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1Q5H1-1", "uniprot_id": "F1Q5H1_DANRE", "id": "F1Q5H1-1", "name": "", "aln": "MPVHPR-DRKENN-HEEMDVDYPEQEASSSDEEDSVSSTASEDGDTSDMDDEDCERRRMECLDEMTNLEKQFTDLKDHLYKERVTQMDLKLQEVMAGSAAEYLEPLATLQENMQIRTKVAGIYRELCLESVRNKYECEMQAASQHWESEKLLLFDTVQSELEEKIRRLEEDRHSIDITSELWNDGLQSRKNKKKDPLSPGKKKKPVVVSGPYIVYMLQDLDILEDWTAIRKAMASMGPHRVKADASLKAEKHHHVARSEEGRLFYDNKWFSRGQAICINRKDEFPTSATITTINHDEVWYKRLDGSKSKIYISQLQKGKYSIKHS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VYI2-1", "uniprot_id": "Q9VYI2_DROME", "id": "Q9VYI2-1", "name": "", "aln": "MPVKNGESDGEGDVSGGESEHSNSSQPHDTSDEEEANECDSDD--SSELDASEIDRRRAEHIEDLLSLERQFNELREQYYVERINLIERQLAEVRSGRSEEFVQPQKELDKKYRTRIEVADVLRKYRLQNIEHKYQSEEQAAVQHFESEKHMALDNLREEFMERIRRLEEDRHNVDISWADWGTDKRQSK-----VRGPGRKK-AVTVTGPYVVYMLREEDIMEDWTIIRKALK-------------------------------------RSSSSATAAGTVTPTSGVSVSLSG----LPAMAGASG-----------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***: . * : . . ..: .:.:*: .. *:* :*::* .: :*** * :::: .**:**.:*::: * **:. :: :* ** :* : *:::* *::: : * :**.: *: *:.:.:**:.* **: ** **** : *.:: *: *:*********.:**: *. :. * .*.:** .*.*:***:****:: **:**** ****: *..: ***.. .::. *:.. ", "identical_positions": 87, "similar_positions": 94, "identity": "26.77%" }, { "cls_id": "homologset.agr.MGI:1196345", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D1E8-1", "uniprot_id": "PLCE_MOUSE", "id": "Q9D1E8-1", "name": "1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon", "aln": "MLLSLVLHTYSMRYLLPSVLLLGSAPTYLLAWTLWRVLSALMPARLYQRVDDRLYCVYQNMVLFFFENYTGVQILLYGDLPKNKENVIYLANHQSTVDWIVADMLAARQDALGHVRYVLKDKLKWLPLYGFYFAQHGGIYVKRSAKFNDKEMRSKLQSYVNAGTPMYLVIFPEGTRYNATYTKLLSASQAFAAQRGLAVLKHVLTPRIKATHVAFDSMKSHLDAIYDVTVVYEGNEKGSGKYSNPPSMTEFLCKQCPKLHIHFDRIDRNEVPEEQEHMKKWLHERFEIKDRLLIEFYDSPDPERRNKFPGKSVHSRLSVKKTLPSVLILGSLTAVMLMTESGRKLYMGTWLYGTLLGCLWFVIKA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0M2Y8-1", "uniprot_id": "A0ABK0M2Y8_RAT", "id": "A0ABK0M2Y8-1", "name": "", "aln": "MLLSLVLHTYSMRYLLPSVLLLGSAPTYMLAWTLWRVLSALLPARLYQRVDDRLYCVYQNMVLFFFENYTGVQILLYGDLPKNKENVIYLANHQSTVDWIVADMLAARQDALGHVRYVLKDGLKWLPLYGFYFAQHGGIYVKRSAKFNDKEMRSKLQSYVNAGTPMYLVIFPEGTRYNATYTKLLSASQAFAAQRGLAVLKHVLTPRIKATHVAFDSMKSHLDAIYDVTVVYEGNEKNSGKYSNPPSMTEFLCKQCPRLHIHFDRIDRKEVPEEQEHMKKWLHERFEIKDKLLVEFYDSPDPERRNKFPGKRVHSRLSVNKTLPSVLILGSLTAAMLMTESGRKLYMGTWLYGTLLGCLWFVIKA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NUQ2-1", "uniprot_id": "PLCE_HUMAN", "id": "Q9NUQ2-1", "name": "1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon", "aln": "MLLSLVLHTYSMRYLLPSVVLLGTAPTYVLAWGVWRLLSAFLPARFYQALDDRLYCVYQSMVLFFFENYTGVQILLYGDLPKNKENIIYLANHQSTVDWIVADILAIRQNALGHVRYVLKEGLKWLPLYGCYFAQHGGIYVKRSAKFNEKEMRNKLQSYVDAGTPMYLVIFPEGTRYNPEQTKVLSASQAFAAQRGLAVLKHVLTPRIKATHVAFDCMKNYLDAIYDVTVVYEGKDDG-GQRRESPTMTEFLCKECPKIHIHIDRIDKKDVPEEQEHMRRWLHERFEIKDKMLIEFYESPDPERRKRFPGKSVNSKLSIKKTLPSMLILSGLTAGMLMTDAGRKLYVNTWIYGTLLGCLWVTIKA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QDN6-1", "uniprot_id": "F1QDN6_DANRE", "id": "F1QDN6-1", "name": "", "aln": "MLLSLVVHTYSLRYWLPTAVMLGTAPAYLLSWSVWRLLSAILPARLYHTVDDRAYSVYQSMVLFFFENYTGVEIVIYGEIPKKKENVVYLSNHQSTADWIIADMLAIRQNAIGHVRYVLKDGLKWLPLYGWYFSQHGGVYVKRSANFDEKAMKKKLSSQTRLSTPMYLVIFPEGTRYNPELKKVISDSQAFAAKQGLAVLNHILTPRMKASHVAIETMREHLDAVYDITVAYEGTLTADGQRRPAPTMPEFLCKECPRVHIHISRVDIKDIPAEPDVFRGWLHQRFEIKDKLLTTFYESEDPAKKSRFPGEGRKSPLSLSKTLPSLLILSGLTFPMLLTESGRKLYLNTWLYGTLIGWIWVGLSP", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******:****:** **:.::**:**:*:*:* :**:***::***:*: :*** *.***.************:*::**::**:***::**:*****.***:**:** **:*:********: ******** **:****:******:*::* *:.**.* . .***************. .*::* ******::*****:*:****:**:***:: *:.:***:**:**.***. *: .*:*.*****:**::***:.*:* :::* * : :: ***:******::* **:* ** ::.:***: :* **:.*****:***..** **:*::*****:.**:****:* :*. :..", "identical_positions": 221, "similar_positions": 106, "identity": "60.55%" }, { "cls_id": "homologset.agr.MGI:1196356", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JUG7-1", "uniprot_id": "IQEC1_RAT", "id": "A0A0G2JUG7-1", "name": "IQ motif and SEC7 domain-containing protein 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------MACRR--------------------------RYLSSLETGSSLSTDRYS-------------------------VEGEAPSSETGT------SLDSPSAYHQGPLVPGSSLSPDHYEHTSVGAYGLYAGP-GPQQRTRRPRLQHSTSVLRKQAEEEAIK------RSRSLSESYELSSDLQDKQVEMLERKYGGRLVTRHAARTIQTAFRQYQMNKNFERLR-SSMSENRMSRRIVLSNMRMQFSFEGPEK-------VHSSYFEGKQVSVTNDGSQLGALVPSECGDLSDP-ALKSPAPSSD--------FADAITELEDAFSRQVKSLAESIDDALNCRSLHSEEVPASDTARARDTEPKP-----GLHGMDHRKLDEMTASYSDVTLYIDEEELSPPLPLSQAGDRPSSTESDLRLRSGGAAQDYWALAHKEDKADTDTSCRSTPSLERPEPRLRVEHLPLLTIEPPSDSSVELSD-----------------RSDRSSLKRQSAYERSLGGQQGSPKHGP-HGGPPKGLPREEPELRPRPPRPLESHLAINGSANRQSKSESDYSDGDNDSINSTSNSNDTINCSSESSSRDSLREQTLSKQTYHKETRNSWDSPAFSN-DVIRKRHYRIGLNLFNKKPEKGIQYLIERGFVPDTPVGVAHFLLQRKGLSRQMIGEFLGNRQKQFNRDVLDCVVDEMDFSAMELDEALRKFQAHIRVQGEAQKVERLIEAFSQRYCVCNPGVVRQFRNPDTIFILAFAIILLNTDMYSPNVKPERKMKLEDFVKNLRGVDDGEDIPRETLIGIYERIRKRELKTNEDHVSQVQKVEKLIVGKKPIGSLHHGLGCVLSLPHRRLVCYCRLFEVPDPNKPQKLGLHQREIFLFNDLLVVTKIFQKKKNSVTYSFRQSFSLYGMQVLLFENQYYPNGIRLTSAVPGADIKVLINFNAPNPQDRKKFTDDLRESVAEVQEMEKHRIESELEKQKGVVRPSMSQ-CSSLKKESGNGTLSRACLDDSYASGE----------GLKRSALSSSLRDLSEAG---KRGRRSSAGSLES--NVE------------------------------------------------FQPFQPSQPPVLCS--------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R0S2-1", "uniprot_id": "IQEC1_MOUSE", "id": "Q8R0S2-1", "name": "IQ motif and SEC7 domain-containing protein 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------MWC----------------------------LHCNSERTQSLLELELDSG------------------------VEGEAPSSETGT------SLDSPSAYHQGPLVPGSSLSPDHYEHTSVGAYGLYAGP-GPQQRTRRPRLQHSTSVLRKQAEEEAIK------RSRSLSESYELSSDLQDKQVEMLERKYGGRLVTRHAARTIQTAFRQYQMNKNFERLR-SSMSENRMSRRIVLSNMRMQFSFEGPEK-------VHSSYFEGKQVSVTNDGSQLGALVPSECGDLSDP-ALKSPAPSSD--------FADAITELEDAFSRQVKSLAESIDDALNCRSLHSEEVPASDTARARDTEPKP-----GLHGMDHRKLDEMTASYSDVTLYIDEEELSPPLPLSQAGDRPSSTESDLRLRSGGAAQDYWALAHKEDKADTDTSCRSTPSLERPEPRLRVEHLPLLTIEPPSDSSVELSD-----------------RSDRSSLKRQSAYERSLGGQQGSPKHGP-HGGPPKGLPREEPELRPRPPRPLESHLAINGSANRQSKSESDYSDGDNDSINSTSNSNDTINCSSESSSRDSLREQTLSKQTYHKETRNSWDSPAFSN-DVIRKRHYRIGLNLFNKKPEKGIQYLIERGFVPDTPVGVAHFLLQRKGLSRQMIGEFLGNRQKQFNRDVLDCVVDEMDFSAMELDEALRKFQAHIRVQGEAQKVERLIEAFSQRYCVCNPGVVRQFRNPDTIFILAFAIILLNTDMYSPNVKPERKMKLEDFVKNLRGVDDGEDIPRETLIGIYERIRKRELKTNEDHVSQVQKVEKLIVGKKPIGSLHHGLGCVLSLPHRRLVCYCRLFEVPDPNKPQKLGLHQREIFLFNDLLVVTKIFQKKKNSVTYSFRQSFSLYGMQVLLFENQYYPNGIRLTSAVPGADIKVLINFNAPNPQDRKKFTDDLRESVAEVQEMEKHRIESELEKQKGVVRPSMSQ-CSSLKKESGNGTLSRACLDDSYASGE----------GLKRSALSSSLRDLSEAG---KRGRRSSAGSLES--NVE------------------------------------------------FQPFQPPQPPVLCS--------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6DN90-1", "uniprot_id": "IQEC1_HUMAN", "id": "Q6DN90-1", "name": "IQ motif and SEC7 domain-containing protein 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------MWC----------------------------LHCNSERTQSLLELELDSG------------------------VEGEAPSSETGT------SLDSPSAYPQGPLVPGSSLSPDHYEHTSVGAYGLYSGPPGQQQRTRRPKLQHSTSILRKQAEEEAIK------RSRSLSESYELSSDLQDKQVEMLERKYGGRLVTRHAARTIQTAFRQYQMNKNFERLR-SSMSENRMSRRIVLSNMRMQFSFEGPEK-------VHSSYFEGKQVSVTNDGSQLGALVSPECGDLSEPTTLKSPAPSSD--------FADAITELEDAFSRQVKSLAESIDDALNCRSLHTEEAPALDAARARDTEPQT-----ALHGMDHRKLDEMTASYSDVTLYIDEEELSPPLPLSQAGDRPSSTESDLRLRAGGAAPDYWALAHKEDKADTDTSCRSTPSLERQEQRLRVEHLPLLTIEPPSDSSVDLSD-----------------RSERGSLKRQSAYERSLGGQQGSPKHGP-HSGAPKSLPREEPELRPRPPRPLDSHLAINGSANRQSKSESDYSDGDNDSINSTSNSNDTINCSSESSSRDSLREQTLSKQTYHKEARNSWDSPAFSN-DVIRKRHYRIGLNLFNKKPEKGVQYLIERGFVPDTPVGVAHFLLQRKGLSRQMIGEFLGNRQKQFNRDVLDCVVDEMDFSTMELDEALRKFQAHIRVQGEAQKVERLIEAFSQRYCICNPGVVRQFRNPDTIFILAFAIILLNTDMYSPNVKPERKMKLEDFIKNLRGVDDGEDIPREMLMGIYERIRKRELKTNEDHVSQVQKVEKLIVGKKPIGSLHPGLGCVLSLPHRRLVCYCRLFEVPDPNKPQKLGLHQREIFLFNDLLVVTKIFQKKKNSVTYSFRQSFSLYGMQVLLFENQYYPNGIRLTSSVPGADIKVLINFNAPNPQDRKKFTDDLRESIAEVQEMEKHRIESELEKQKGVVRPSMSQ-CSSLKKESGNGTLSRACLDDSYASGE----------GLKRSALSSSLRDLSEAG---KRGRRSSAGSLES--NVE------------------------------------------------FQPFEPLQPSVLCS--------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B5E1-1", "uniprot_id": "A0ACD6B5E1_DANRE", "id": "A0ACD6B5E1-1", "name": "", "aln": "-------------------------------------------------------------------------MDGHFAYIDMENPTENPNKAAEYLKELNKIIETQQELLEKQKNRIEELEQQVCDLCQENACLKDQHQRHLATCRLQQQGNSHPTLGAIKENVIQEKNESEGLRVSNVRRHASLPLDVTDNPGNFIVSHCQRSYPCRKWKSASLGVEGEAPGGESGP------SLDNSGGYLRGPVSRSAIISGEHFDGPPLYAH-------EVRQRPRRPKLQHSQSILRKQAEEEAIK------RSRSLSESYELSTDLQDKQVEMLERKYGGRFITRHAARTIQTAFRQYQMNKNFERLR-SSMSENRMSRRIVLSNMRMQFSFEGPEK-------VHSSYFEGKQVSLTDDGSKLGALVQSERGEMVPA-NMKSPAVQSD--------FTDAITELEDVFSRQVKSLAESIDDALNCRSLHGDEGQSEATRGHPDLEQEVTYQVKPSHGSEHRKRDEMTASYSDVTLYIDEEELSPPLPLSQSVDRPSSTESDLRIRSLNSSQDYWSLAHKDEKADTDTSCRSTPSLECQEQRLRIDHLPLLTIEPPSDSSVELSD-----------------RSDRSSLKRQNAYDRGIASQQGSPKHIPSHALPPRGPAREDEAPRHRP-RQLESHLAINGTANRQSKSESDFSDGDNDSINSTSNSNDTINCSSESSSRDSLREQTLSKQTYHKETRNSWDSPAFSN-DIIRKRHYRIGLNLFNKKPEKGIQYLIERGFVPDTPVGVAHFLLQRKGLSRQMIGEFLGNRQKQFNRDVLDCVVDEMDFSAMELDEALRKFQAHIRVQGEAQKVERLIEAFSQRYCICNPGVVRQFRNPDTIFILAFAIILLNTDMYSPNVKPERKMKLEDFVKNLRGVDDGEDIPREMLVGIYERIRKRELKTNEDHVSQVQKVEKLIVGKKPIGSLHHGLGCVLSLPHRRLVCYCRLFEVPDPNKPQKLGLHQREIFLFNDLLVVTKIFQKKKNSVTYSFRQSFSLYGMQVLLFENQYYPNGVRLTSALPGADIKVLINFNAPNPQDRKKFTDDLRESIAEVQEMEKYRIESELEKQKGVVRPSISQ-SSGLKKETGNGNLSRTSLDDSYAMGE----------GLKRSALSSSLRDLSDAG---KRGRRSSAGSLDS--NMEGSIISSPHIRRRATSSRDCPSRQQSIPNSSSLLGSLFGTKRGKSPSLPSQSSHPSHPTLISHTPHPSNLHHTARDGVTVTETQAQMHPHHAQFCHMQNPPPYHHHHHYHPPAHIQHPPHQYHPPPGPSSSHSHSHSQHGHGPHPSHSSHPSHSQHAPHHHSQPPAPPPAASSTKPKHSGISTVV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB13A8W6-1", "uniprot_id": "A0AB13A8W6_DANRE", "id": "A0AB13A8W6-1", "name": "", "aln": "----------------------------------------------------------------------------------MDSRTENPTKAAGYLKELNKIIETQQTLLERQKRRIFELEQHVSDLCAENSRLRLEYQRHLLTCRLRSIRENSP------------EQQSEYGGSRIVRRHASLPVEMTDSPNSLRSAVCRRTVPCRQWKSASLGVEGTVESSEPGP------SVDTSIGYGRGPVTHSSSLSPDQSEG-SLYSHSIQSGP----QRPQRPKLQHSQSILRKQAEEEAIK------RSRSLSESYELSTDLQDKKVEMLERKYGGRFITRHAARTIQTAFRHYQMNKNFERLR-SSMSENRMSRRILLSNMRMQFSFEAPEK-------VHSSFFEGRQMSLMEESSHIGAMVQP--GEKVPV-ILEAPETQND--------LTDTITELEDTFSKQVKSLAESIDDALNCRSLHKEEIQPEQTVCELQQKRELP------QPDEHHRLDEI----CDVTLFIDEEELSP---LVQ----PSSAESDQHTQSVSASQEYWSMD-----ANMDTSARSTPSLDYQSPKLCVD-LPVLTIEPPSDSSADASD-----------------RSEQGLVQTQNVPKQTTAAPRANPKHGLPARVP--SLSGEEEPLRHRQ---VVSHLATNG--SRQSKSESDFSDGDNDSINSNSNSIDTINSESSSS------QQNLSKQTYHKDTRNSWDSPASSS-DIMRKRQYRIGLNLFNKKPEKGIQYLTERGFIPDTPVGVAHFLLQRKGLSRQMIGEFLGNRQKQFNRDVLDCVVDELDFSGMELDEALRKFQAQIRVQGEAQKVERLIEAFSQRYCICNHDVVRQFRNPDTIFILAFAIILLNTDMYSPNVKIERKMKLEDFVKNLRGVDDGEDIPREMLVGIYERIQKKELKTNEDHVSQVQKVEKLIVGKKQMGSLHHGLGCVLSQAHRRLVCYCRLFEVPDPNRLQKLGQHQREIFLFNDLLVVTKIFQKKKNSVTYSFRQSFSLYGMQVMLFENQFYPNGIRLTSAIPGADFKVLINFNAPNIQDRKRFISDLRESIAEVQEMEKYRIESELEKQKGVVRPSMSQSMSGLKKETGNGSMGRTSLDDSYAMGE----------GLKRSALSSSLRDLSEAG---LHL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VP80-1", "uniprot_id": "Q9VP80_DROME", "id": "Q9VP80-1", "name": "", "aln": "MSEADLKNLSQNSDGDQELLLHQTTQSLLMASSIMFVGNQGGPGGSAGGVAPPGPVSLPLPLSINMPHHHVHAMPYNVDELLRENNALHAKIKELSLERDRLLCEVSNLRLELDMSELKRLPVDLDDNFPQKSLERSGSTQYELAGAQQPGSANASTCTDSGSVG----GYVYLQNHYAPGAHSSSAAINYPAQQHPQMVYQIQQYPTCHQQQQQQHLQQQQHLHQTGAGHYMQVTATGGGQYHHHHMLHGHGHHAHHHGGAVVIAGSGVGTGLGSGATSVIMQHQQQQQQQQNMHKKNSIRNGGDVLKRTRAQSAYELSQDLLEKQIELLERKYGG-VRARNAAVTIQRAFRHYMMVKKFASITAMAKAEKRLSRRMVVTASSLGLAEEGASSSSAYGSATESQLTEQQQQQQAQQQQQPRVTIMAGPAGAASPGLSRTPPTRSLSMRERRQLDCSPIPRSQSGASPASISSSTVSTSALASHPHVNLLHAAEPHYYNAQALPQGAAYYTSYHGSPHDLSYASSADTSLNASWVNTSGHSPHTPYYSAAQIYMRPKGGSTTPTPSCSGSTGSGSGGSGSGSSKKVPPEVPKRTSSITAQQQTQLLLLQRQTPPPPSLLRTNGLCKTAENGSLTSVQSSGSDSSVTSAERNLNSDLGSDRSNSPHTWKRGTALNSSQQFSTHSADSAGAVSGGGVGVAGGAGVYAAQMQAAVAAATAAGGMPPADDHAISSHTSAAQYEQHEQQQHEQQQLQAAAAAAGVAQNYKMSETIRKRQYRVGLNLFNKKPEKGITYLIRRGFLENTPQGVARFLITRKGLSRQMIGEYLGNLQNQFNMAVLSCFAMELDLSGRQVDVALRKFQAYFRMPGEAQKIERLMEIFSQRYCECNADIVGRLRSSDTIFVLAFAIIMLNTDLHTPNLKPERRMRVEDFIKNLRGIDDCHDIDKDMLMGIYDRVKSDEFKPGSDHVTQVMKVQATIVGKKPN----------LALPHRRLVCYCRLYEIPDVNKKERPGVHQREVFLFNDLLVITKIFSKKKTSVTYTFRNSFPLCGTVVTLLDMPNYPFCIQLSQKVDG---KILITFNARNEHDRCKFAEDLKESISEMDEMESLRIEAELERQKSARNRAPGNAENRDSGVADVEVCPCPYQQGSQASGEQAPNSADNSQQLKRSALSNSLLDMHEQFGNEKPQRRGSVGSLDSGMS---------------------------------------------------ISFQSTTTSSASRENAAAIAAAANAAAAAKMRFNMPPTAAIATPSNVYAAPGMQAYTHANFVQQSQAAYMLQQQQMLQQQAQMQAQAQAQAQAQAQAQAQAQAQAQAQPLTGRIPGRERKASRTDENGRSTEV--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: :.*. : * : : . .: : : . : *:. . :: ::::*: : ..:**** ** :*::*:******* . :*:** *** ***:* * *:* : : :*:*:***:::: : :: *.... ..*. * :* . :: .: . : . . .:* . ..*.. :. * * : .** .:. . : : : * . : ::: . ** . .:.. : ..: . : .. .. ..*. * :* :.*. .* :: *: . . : . .. :... * . . . . :. * . : . . . . : . . . .:*.. :.:: :* .:* : : : : . : :***:**:************: ** .***: :** ***:**: ***********:*** *:*** **.*.. *:*:* ::* ******* :*: *****:***:* ****** ** .:* ::*..****:******:****:::**:* **:*::***:*****:** .** :: *:***:*::. *:*...***:** **: ***** *: .**********:*:** *: :: * ****:********:****.***.****:**:**.* * * *:: ** ::*:. : * *:**.*** * :** :* .**:**::*::***. ***:***:**.. . : .: . . :. . :.* * ** *******.** *: : ", "identical_positions": 284, "similar_positions": 264, "identity": "20.34%" }, { "cls_id": "homologset.agr.MGI:1196365", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZFM4-1", "uniprot_id": "D3ZFM4_RAT", "id": "D3ZFM4-1", "name": "Dehydrodolichyl diphosphate synthase complex subunit NUS1", "aln": "-------------------------------------------MTGLYELVWRVLHLLFCLYRTLTSWLRVRFGTWNWIWRRCCRAASAAVLAPLGFTLRKLPAVGRNRRHHRHPHRGPGP----AATHPRLR--------WRADGRSLQKLPVHMGLVITEEVQ-------EPSFSDIASLVVWCMAVGISYISVYDH--QGIFKRNNSRLMDEILKQQQELLG----QDCSKYSAEFAN-------------------SNDKDDQVLNCPSAVKVLSPEDGKADIVRAAQDFCQ---------SVAQQQRRPTELGVELLDSLLS-SHGFPDPDLVLKFGPVDSTLGFLPWQIRLTEIISLPSHSNISYEDLFSALRQYAACEQRLGK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99LJ8-1", "uniprot_id": "NGBR_MOUSE", "id": "Q99LJ8-1", "name": "Dehydrodolichyl diphosphate synthase complex subunit Nus1", "aln": "-------------------------------------------MTGLYELVWRVLHALLCLHLTLTSWLRVRFGTWNWIWRRCCRAASAAVLAPLGFTLRKPRAVGRNRRHHRHPHGGPGPGPGPAATHPRLR--------WRADVRSLQKLPVHMGLLVTEEVQ-------EPSFSDIASLVVWCMAVGISYISVYDH--QGIFKRNNSRLMDEILKQQQELLG----QDCSKYSAEFAN-------------------SNDKDDQDLNCPSAVKVLSPEDGKADIVRAAQDFCQ---------LVAQQQRKPTDLDVDLLGSLLS-SHGFPDPDLVLKFGPVDSTLGFLPWQIRLTEIVSLPSHLNISYEDFFSALRQYAACEQRLGK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96E22-1", "uniprot_id": "NGBR_HUMAN", "id": "Q96E22-1", "name": "Dehydrodolichyl diphosphate synthase complex subunit NUS1", "aln": "-------------------------------------------MTGLYELVWRVLHALLCLHRTLTSWLRVRFGTWNWIWRRCCRAASAAVLAPLGFTLRKPPAVGRNRRHHRHPRGGSCL----AAAHHRMR--------WRADGRSLEKLPVHMGLVITEVEQ-------EPSFSDIASLVVWCMAVGISYISVYDH--QGIFKRNNSRLMDEILKQQQELLG----LDCSKYSPEFAN-------------------SNDKDDQVLNCHLAVKVLSPEDGKADIVRAAQDFCQ---------LVAQKQKRPTDLDVDTLASLLS-SNGCPDPDLVLKFGPVDSTLGFLPWHIRLTEIVSLPSHLNISYEDFFSALRQYAACEQRLGK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DHR8-1", "uniprot_id": "NGBR_DANRE", "id": "Q6DHR8-1", "name": "Dehydrodolichyl diphosphate synthase complex subunit nus1", "aln": "-------------------------------------------MASLYEMVWRFLHALLYLQRAIVAWFRV------HIWR--WKLAVVDLLLPLALGFHNQKKTG--------PKG--------TRTSRRVR--------WGADGRTLEKLPLHVGLLVTEE---------EIHYTDIANLVVWCMAVGISYVSVYDN--QGVFKRNNSRLMEEILKQQQELLG----MGSSKYSVEILKN-----------------GTNKQEHQVLSCQSMVKVLSPDDGRLSIVQAAQQLCR---------AVEQKEKTSKDINVSVLDSLLKESKNIPDPDLVLKFGTVQSTLGFLPWHIRLTEIISMPSHIDASYDDLYDALQRFAGCEQRLGK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q12063-1", "uniprot_id": "UPPS_YEAST", "id": "Q12063-1", "name": "Dehydrodolichyl diphosphate synthase complex subunit NUS1", "aln": "MPTMIKKDDKAMEPPNEKPHRKIERDDVPESSNHIPPPESGVLKGGKVNSKTRALKAVTSIIADADENPQKKVNNETNGVQKQKTEDLSKRIGKFEYLFYKFLLVLLYICFGLFRYGQYQYNKMKLRIFSIIYNHAYTPQLIRQDVIPLKKIPKRLAAILEVKPVGDVGGGVTGLLNDASEIVCWTVSAGIKHLMLYDY--DGILQRNVPELRMEIHSNLAKYFGP---AHVPNYAVKIPHSNKIFYNLDGIETETDVGNEIEANQEKDKIAIEISLLSNRDGRETIVDLTKTMAE---------LCAVNELSVSDITMDLVDSELK-QLVGPEPDLLLYFGPSLDLQGFPPWHIRLTEFYWEKDNNEVIYSVFIRGLRQYAGCKVNVGK", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VPX8-1", "uniprot_id": "Q9VPX8_DROME", "id": "Q9VPX8-1", "name": "ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyldiphosphate specific]", "aln": "----------------------------------------------MIEVLCLLLGRILLLLVGGYELMWR-------------LRERLNALAVRSYDLWRSKAAR-------------------EAHERRVL---------ADCRSQLTKTPQHLVLVISPVDAG-------VDAVLLSRIFDFALDVGIKHVSLYDRRTKGRGYVDMADLCRSTNADTGSCLKWPPVASPSKLENQPKNGQ----------------KTNGYVNGSHSPQLQLHQISASDGHALIADVCRELYEDSKTELVQSLLKQKREALTEQISDMLSKRLG--FEAPEPELGIVFARQTCTYGLLPWHARFTEFHTHPSGRHFDVETFASILCKYSRCEQRWGT", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * : : : : . . : * * * :: :: : :. : : .**.:: :** .* : . * . : . : .: : : . . : :* **: *. : : . :. .: . : . * *:*:* : *. *: **: *:**: . . . : * ::: *: . *.", "identical_positions": 28, "similar_positions": 67, "identity": "7.18%" }, { "cls_id": "homologset.agr.MGI:1196368", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Y2V2-1", "uniprot_id": "CHSP1_HUMAN", "id": "Q9Y2V2-1", "name": "Calcium-regulated heat-stable protein 1", "aln": "MSSEPPPPP-QPPTHQASVGLLDTPRSRERSPSPLRGNVVPSPLPTRRTRTFSATVRASQGPVYKGVCKCFCRSKGHGFITPADGGPDIFLHISDVEGEYVPVEGDEVTYKMCSIPPKNEKLQAVEVVITHLAPGTKH---ETWSGHVISS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9WU49-1", "uniprot_id": "CHSP1_RAT", "id": "Q9WU49-1", "name": "Calcium-regulated heat stable protein 1", "aln": "MSSEPPPPP-QPPTHQTSIGLLDTPRARDRSPSPLRGNVVPSPLPTRRTRTFSATVRASQGPVYKGVCKCFCRSKGHGFITPADGGPDIFLHISDVEGEYVPVEGDEVTYKMCSIPPKNEKLQAVEVVITHLAPGTKH---ETWSGHVISS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CR86-1", "uniprot_id": "CHSP1_MOUSE", "id": "Q9CR86-1", "name": "Calcium-regulated heat stable protein 1", "aln": "MSSEPPPPPLQPPTHQTSVGLLDTPRTRDRSPSPLRGNVVPSPLPTRRTRTFSATVRASQGPVYKGVCKCFCRSKGHGFITPADGGPDIFLHISDVEGEYVPVEGDEVTYKMCSIPPKNEKLQAVEVVITHLAPGTKH---ETWSGHVISN-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9VVA0-1", "uniprot_id": "Y9705_DROME", "id": "Q9VVA0-1", "name": "Cold shock domain-containing protein CG9705", "aln": "-MTEP-----RTPEKLLAA---KPPVLHHNSHSPNASLQLPSPIITRRTRTASTSARALENPVVTGMVKSFSRTKGHGFITPNAGGEDVFCHVSDIEGEYVPMPGDEVKYRLCAIPPKYEKHQAVHVQISHLTPEVHHKWEEPFYGGSSPAK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :** :.* : : ..* :..* ** . :***: ****** *::.** :.** .*: *.*.*:******** ** *:* *:**:******: ****.*::*:**** ** ***.* *:**:* .:* *.: * . ", "identical_positions": 69, "similar_positions": 39, "identity": "45.39%" }, { "cls_id": "homologset.agr.MGI:1196370", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B5TVM2-1", "uniprot_id": "ILDR2_MOUSE", "id": "B5TVM2-1", "name": "Immunoglobulin-like domain-containing receptor 2", "aln": "MPAFPTLDLDGKLGKMDRVVLGWTAVFWLTAMVEGLQVTVPDKKKVAMLFQPTVLRCHFSTSSHQPAVVQWKFKSYCQDRMGESLGMSSPRAQALSKRNLEWDPYLDCLDSRRTVRVVASKQGSTVTLGDFYRGREITIVHDADLQIGKLMWGDSGLYYCIITTPDDLEGKNEDSVELLVLGRTGLLADLLPSFAVEIMPEWVFVGLVILGIFLFFVLVGICWCQCCPHSCCCYVRCPCCPDSCCCPQALYEAGKAAKAGYPPSVSGVPGPYSIPSVPLGGAPSSGMLMDKPHPPPLAPSDSTGGSHSVRKGYRIQADKERDSMKVLYYVEKELAQFDPARRMRGRYNNTISELSSLHDDDSNFRQSYHQMRNKQFPMSGDLESNPDYWSGVMGGNSGTNRGP-ALEYNKEDRESFRHSQQRSKSEMLSRKNFATGVPAVSMDELAAFADSYGQRSRRANGNSHEARAGSRFERSESRAHGAFYQDGSLDEYYG-RGRSREPPGDGERGWTYSPAPARRRPPEDAPLPRLVSRTPGTAPKYDHSYLSSVLERQARPESSSRGGSLETPSKLGAQLGPRSASYYAWSPPTTYKAGASEGEDEDDAADEDALPPYSELELSRGELSRGPSYRGRDLSFHSNSEKRRKKEPAKKPGDFPTRMSLVV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZGJ1-1", "uniprot_id": "D3ZGJ1_RAT", "id": "D3ZGJ1-1", "name": "", "aln": "MPAFPTLDLNGKLGKMDRVVLGWTAVFWLTAMVEGLQVTVPDKKKVAMLFQPTVLRCHFSTSSHQPAVVQWKFKSYCQDRMGESLGMSSPRAQALSKRNLEWDPYLDCLDSRRTVRVVASKQGSTVTLGDFYRGREITIVHDADLQIGKLMWGDSGLYYCIITTPDDLEGKNEESVELLVLGRTGLLADLLPSFAVEIMPEWVFVGLVILGIFLFFVLVGICWCQCCPHSCCCYVRCPCCPDSCCCPQALYEAGKAAKAGYPPSVSGVPGPYSIPSVPLGGAPSSGMLTDKPHPPPLAPSDSTGGSHSVRKGYRIQADKERDSMKVLYYVEKELAQFDPARRMRGRYNNTISELSSLHDDDSNFRQSYHQMRNKQFPMSGDVESNPDYWSGVMGGNSGTNRGP-ALEYNKEDRESFRHSQPRSKSEMLSRKNFATGVPAVSMDELAAFADSYGQRSRRANGNSHEARAGSRFERSESRAHGAFYQDGSLDEYYG-RGRSREPPGDGERGWTYSPAPARRRPPDDAALPRLVSRTPGTAPKYDHSYLSSVLERQARPESNSRGGSLETPSKLGAQLGPRSASYYAWSPPATYKAGASEGEDEDDAADEDALPPYSELELSRGELSRGPSYRGRDLSFHSNSEKRRKKEPAKKTGDFPTRMSLVV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q71H61-1", "uniprot_id": "ILDR2_HUMAN", "id": "Q71H61-1", "name": "Immunoglobulin-like domain-containing receptor 2", "aln": "---------------MDRVLLRWISLFWLTAMVEGLQVTVPDKKKVAMLFQPTVLRCHFSTSSHQPAVVQWKFKSYCQDRMGESLGMSSTRAQSLSKRNLEWDPYLDCLDSRRTVRVVASKQGSTVTLGDFYRGREITIVHDADLQIGKLMWGDSGLYYCIITTPDDLEGKNEDSVELLVLGRTGLLADLLPSFAVEIMPEWVFVGLVLLGVFLFFVLVGICWCQCCPHSCCCYVRCPCCPDSCCCPQALYEAGKAAKAGYPPSVSGVPGPYSIPSVPLGGAPSSGMLMDKPHPPPLAPSDSTGGSHSVRKGYRIQADKERDSMKVLYYVEKELAQFDPARRMRGRYNNTISELSSLHEEDSNFRQSFHQMRSKQFPVSGDLESNPDYWSGVMGGSSGASRGPSAMEYNKEDRESFRHSQPRSKSEMLSRKNFATGVPAVSMDELAAFADSYGQRPRRADGNSHEARGGSRFERSESRAHSGFYQDDSLEEYYGQRSRSREPLTDADRGWAFS--PARRRPAEDAHLPRLVSRTPGTAPKYDHSYLGSARERQARPEGASRGGSLETPSKRSAQLGPRSASYYAWSPPGTYKAGSSQDDQED--ASDDALPPYSELELTRG-----PSYRGRDLPYHSNSEKKRKKEPAKKTNDFPTRMSLVV", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ****:* * ::***************************************************************.***:*******************************************************************************:**********************************:**:**************************************************************************** *********************************************************************::*******:****.****:***:*************.**:.*** *:************** **********************************.***:*******.************..****.**:**** *.***** *.:***::* ******.:** ********************.*. *******. *********** .**************** *****:*:.::** *.:***********:** ********.:******:********..**********", "identical_positions": 577, "similar_positions": 49, "identity": "87.03%" }, { "cls_id": "homologset.agr.MGI:1196373", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O54916-1", "uniprot_id": "REPS1_MOUSE", "id": "O54916-1", "name": "RalBP1-associated Eps domain-containing protein 1", "aln": "MEGLTLSDAEQKYYSDLFSYCDIESTKKVVVNGRVLELFRAAQLPNDVVLQIMELCGATRLGYFGRSQFYIALKLVAVAQSGFPLRVESINTVKDLPLPRFVASKNEQESRLAASYSSDSENQGSYSGVIPPPPGRGQVKKGPGSHDAVQP-RPSAEQQ-EPVSPVVSPQQSPPTSPHTWRKHSRHPSGGNSERPLTGPGPFWSPFGDAQAGSSAGDAVWSGQSPPPPQDNWVSFADTPPTSALLTMHPASVQDQTTVRTVASAATANEIRRQSSSYEDPWKITDEQRQYYVNQFKTIQPDLNGFIPGSAAKEFFTKSKLPILELSHIWELSDFDKDGALTLDEFCAAFHLVVARKNGYDLPEKLPESLMPKLIDLEDSADVGEQPGEVGYSGSPAEAPPSKSPSMPSLNQTWPELNQSSEQWETFSERSSSSQTLTQFDSNIAPADPDTAIVHPVPIRMTPSKIHMQEMELKRTSSDHTNPTSPLLVKPSDLSEENKINSSVKFPSGNTV-DGYSSSDSFPSDPEQIGSSVTRQRSHSGTSPD---NTAPPPPPPRPQPSHSRSSSLDMNRTFAVT--TGQQQAGVVAHPPAVPPRPQPSQAPGPSVHRPVDADGLITHTSTSPQQIPEQPNFADFSQFEVFAASNVSEEQDSEAEKHPEVLPAEKASDPSSSLRAAQADSKAEEKTATNVPANVSKGTTPLAPPPKPVRRRLKSEDELRPDVDEHTQKTGVLAAVLTSQPSIPRSVGKDKKAIQASIRRNKETNTVLARLNSELQQQLKDVLEERISLEVQLEQLRPFSHL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LDV5-1", "uniprot_id": "A0ABK0LDV5_RAT", "id": "A0ABK0LDV5-1", "name": "", "aln": "MEGLTLSDAEQKYYSDLFSYCDIESTKKVVVNGRVLELFRAAQLPNDVVLQIMELCGATRLGYFGRSQFYIALKLVAVAQSGFPLRVESINTVKDLPLPRFVASKNEQESRHAASYSSDAENQSAYAGVIPPPPGRGQVKKAPGSHDAAQP-RPSADQQ-EPASPVVSPQQSPPTSPHTWRKHNRHPSGGNSERPLAGPGPFWSPFGDAQSGSSAGDAVWSGHSPPPPQENWVSFADTPPTSALLTMHPASVQDQTTVRTVASATTANEIRRQSSSYDDPWKITDEQRQYYVNQFKTIQPDLNGFIPGSAAKEFFTKSKLPILELSHIWELSDFDKDGALTLDEFCAAFHLVVARKNGYDLPEKLPESLMPKLIDLEDSADVGDQPGEVGYPGSPAEAPPSKSPSMPSLNQTWPELNQSSEQWETFSERSSSSQTLTQFDSNIAPADPDTAIVHPVPIRMTPSKIHMQEMELKRSSGDHTNPTSPLLVKPSDLSEENKINSSVKFPSGNTVADGYSSSDSFPSDPEQIGSNGARQRSHSGASPD---NTAPPPPPPRPQPSHSRSSSLDMNRTFAVA--TGQQQAGVVTHPPAVPPRPQPSQAPGPSVHRPVDADGLITHTSTSPQQIPEQPNFADFSQFEVFAASNVSEEQDSEAEKHPEVLPAEKASDPSSSLRVAQADSKIEEKTAAGVPANVSKGTTPLAPPPKPVRRRLKSEDELRPDVDEHTQKTGVLAAVLASQPSIPRSVGKDKKAIQASIRRNKETNTVLARLNSELQQQLKDVLEERISLEVQLEQLRPFSHL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96D71-1", "uniprot_id": "REPS1_HUMAN", "id": "Q96D71-1", "name": "RalBP1-associated Eps domain-containing protein 1", "aln": "MEGLTLSDAEQKYYSDLFSYCDIESTKKVVVNGRVLELFRAAQLPNDVVLQIMELCGATRLGYFGRSQFYIALKLVAVAQSGFPLRVESINTVKDLPLPRFVASKNEQESRHAASYSSDSENQGSYSGVIPPPPGRGQVKKGSVSHDTVQP-RTSADAQ-EPASPVVSPQQSPPTSPHTWRKHSRHPSGGNSERPLAGPGPFWSPFGEAQSGSSAGDAVWSGHSPPPPQENWVSFADTPPTSTLLTMHPASVQDQTTVRTVASATTAIEIRRQSSSYDDPWKITDEQRQYYVNQFKTIQPDLNGFIPGSAAKEFFTKSKLPILELSHIWELSDFDKDGALTLDEFCAAFHLVVARKNGYDLPEKLPESLMPKLIDLEDSADVGDQPGEVGYSGSPAEAPPSKSPSMPSLNQTWPELNQSSEQWETFSERSSSSQTLTQFDSNIAPADPDTAIVHPVPIRMTPSKIHMQEMELKRTGSDHTNPTSPLLVKPSDLLEENKINSSVKFASGNTVADGYSSSDSFTSDPEQIGSNVTRQRSHSGTSPD---NTAPPPPPPRPQPSHSRSSSLDMNRTFTVT--TGQQQAGVVAHPPAVPPRPQPSQAPGPAVHRPVDADGLITHTSTSPQQIPEQPNFADFSQFEVFAASNVNDEQDDEAEKHPEVLPAEKASDPASSLRVAKTDSKTEEKTAASAPANVSKGTTPLAPPPKPVRRRLKSEDELRPEVDEHTQKTGVLAAVLASQPSIPRSVGKDKKAIQASIRRNKETNTVLARLNSELQQQLKDVLEERISLEVQLEQLRPFSHL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B7S1-1", "uniprot_id": "A0A8M2B7S1_DANRE", "id": "A0A8M2B7S1-1", "name": "", "aln": "MESLTLSDVEQKYYSELFLSCDVDNAKKVASNGKVLELFRAAQLSNEVVLQITELCGATRLGHFGRSQFYIALKLIALAQSGLPLRLESLNTVRDLPLPRFVMGKNEQETRHMVMFT-DAENQG---PFLPRPPGRVQAKKVS-AHEMIQPCVPTADPQPDTTSPVVSPHQSPPTSPLAWRKHKRQASGGNVDRQPSVPGVVWPHFREAQPGPVPGDGMWSAHSPPPVQESWVSFTDTPPSSTLPMHPPSAQTESSTVRTVPSAMTTNEIQRQTSGYDDPWKITDEQRQYYINQFKTIQADLTGLIPGSAAKEFFTKSKLPILELSHIWELSDFDKDGALTLDEFCAAFHLVVARKNGYDLPEKLPESLMPKLIDLDDSAGVPEPAPEVGFSASPVEVTPNKSPSMPSLNQNWPELNQSNEQWETFSERSSSSQTLTQFDSNIAPADPDTAIVHPVPIRMTPSKIHMQEMELKRTGSDHTHPTSPLMTKPPELSDETKLAAAIKFP-GTAVGDGYSSSDSFTSDQEPISSAVNRQRSHSGTSPEGLKVVAPPPPPPRPHASHSRSSSLDMNRNFAAVPAAGSQQAGVVAFPPAVPPRPLPTQTSVPHGHRSVEGDGLPAHTSTSPQQMPEQPNFADFSQFKAFAVDQPADDGENPSDGG----QAERLPEAAGTMRTAKNDVQAEERNATTVNS--AKVSTPLAPPPKPVRRRLKSEDELRPDVDDLPQKSNVIATVLATQPSIPRSLGKDKKAIQASIRRNKETNTVLARLNSELQQQLKDLLEERISLEVQLEQLRPFSHL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P39013-1", "uniprot_id": "END3_YEAST", "id": "P39013-1", "name": "Actin cytoskeleton-regulatory complex protein END3", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPKLEQFEIKKY-------WQIFSG--------LKPIENKVN----HDQVLPILYNSKLDSSVLNKIWFLADIDDDDNLDFEEFVICMRLIFDMVN-------------------KNISSVPDELPDWLIPGSKVNLIKERKKRKQIENADLPPKKEIKVDWYMSPDDLN---QYEKIYNSCAKLTDGTITFNELSTKLSTKFFNISKTDLNKVWS---------LINPQNLP-------------------------SIDRDPTFYFIHCLRQRNDLGAEIP------ASLPNSLAEVCNKKQLSYDLR-------------------------------SSQPPTKRKEEAN----------------------------EVDNLRDNGQNS-------------SSDSSGSNVLSNEDSIKQKYASLTDDQVANMREQLEG--------------------------------LLNYKKSEKTQGGSKLSKRINIRSITDDLDNIEQQVEVLENYLNNKRHELQALQAEIN--------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P36115-1", "uniprot_id": "IRS4_YEAST", "id": "P36115-1", "name": "Increased rDNA silencing protein 4", "aln": "-----------------------------------------------------MRLSFGKQRYHGGTTVTLTEQGASDSLRAAQAIFQNHSNEVSSPCPPVTVSRNPQTRLSEPSLQKSGRKQEQKKARIR-------------------------------TKQVPKIKTTAPNDVELSKKHRSSPAGKDNVSSTAQMAAALAHSQSKLSS--------DNNSSHSSALDTLKVLETPNLNGLLGIHSRSSSRNGSNESLTPGQRTPDNRSQE---NLLTSFSSGRRLSSSSMEPATNKDSNKALPKRRPSPPLQSSLVGSGQLHENENLSSISIDSRHSLNPDTSDVISNRSQTS--------LSQTINQLSLCESEPSIASSNTTTTTSNQGSGLPNLVPNYSSDMRKKKLVNKFKRKVFGSKPKHLSSQYEMDASSEELGQHEQQPSMRFKTTLRKTSVSTNAENDHASSLHEGNLRYKYNPSNDTYDVYDDTD--------------------SDSESDQNQDALTKPRKRDRIKRKIR----------NSANKTAHHRPIHRTRDRKFNED-------------------KPWKSHTDITFVTDNERKR------------------------YESMWVSNRHRHLNLLSWWP-------SITGDSGAINTLPEDGLILGIIVRDIWKRSNLPNSLLAEIYTKVDTRKDGTLDRKSFIVGMWLVDQCLYGRKLPNVVEQCVWDSVDRYASTTVVPVSTLKAMAKQKRKQMKEEIKNIKKENRVVLVDHNSSS-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : .: . . : . . : .* : * . *:.:. *. :: . . .. ..: . . . . : : .. . .. . . . : :. : .: . . .. :: . * *:*. . . . .: : : . ..: . : . :. .. : . * . . .: . : . ::: ::: .* : .: : ", "identical_positions": 9, "similar_positions": 95, "identity": "1.12%" }, { "cls_id": "homologset.agr.MGI:1196377", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0R7V5-1", "uniprot_id": "M0R7V5_RAT", "id": "M0R7V5-1", "name": "Tumor necrosis factor alpha-induced protein 3", "aln": "--MAEQLLPQALYLSNMRKAVKIRERTPEDIFKPSNG--IIHHFKTMHRYTLEMFRTCQFCPQFREIIHKALIDRSVQASLESQKKLNWCREVRKLVALKTNGDGNCLMHAACQYMWGVQDTDLVLRKALCSTLKETDTRNFKFRWQLESLKSQEFVETGLCYDTRNWNDEWDNLVKMASADTPAARSGLQYNSLEEIHIFVLSNILRRPIIVISDKMLRSLESGSNFAPLKVGGIYLPLHWPAQECYRYPIVLGYDSQHFVPLVTLKDSGPEIRAVPLVNRERGRFEDLKVHFLTDPEHEMKEKLLKEYLMVLEIPVQGWDHGTTHLINAAKLDEANLPKEINLVDDYFELVQHEYKKWQENGDQGRRGAHAQNPLEASTPQLSLMDIKCETPNCPFFMSVNTQPLCHECSERRQKNQSKLPKLNSKLGPEGGLPAVGLGSSN--------WNPEETAGGPHSAPPTAPSLFLFSETTAMKCRSPGCPFTLNVQHNGFCERCHNARQMSAS-------HTAD------PGKCQACLQDVTRTFNGICSTCFKRTTAEPTSSLTSSVPPSCHQRSKSDPSQLIQSLTPHSCHRTGNAVPSGYLSQTSRTPADRTGTSKCRKAGCMYFGTPENKGFCTLCFIEYRENKQSVTASGKAASSAPR-FQNNIPCLGRECGTLGSTMFEGYCQKCFIEAQNQRFHEAKRPEEQ---LRSSQRREMPRTTQGASRPKCARASCKNILACRSEELCMECQHLSQRIASLAHRGEPTPEEPPKQRCRAPACDHFGNAKCNGYCNECYQFKQMYG-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60769-1", "uniprot_id": "TNAP3_MOUSE", "id": "Q60769-1", "name": "Tumor necrosis factor alpha-induced protein 3", "aln": "--MAEQLLPQALYLSNMRKAVKIRERTPEDIFKPTNG--IIYHFKTMHRYTLEMFRTCQFCPQFREIIHKALIDRSVQASLESQKKLNWCREVRKLVALKTNGDGNCLMHAACQYMWGVQDTDLVLRKALCSTLKETDTRNFKFRWQLESLKSQEFVETGLCYDTRNWNDEWDNLVKMASADTPAARSGLQYNSLEEIHIFVLSNILRRPIIVISDKMLRSLESGSNFAPLKVGGIYLPLHWPAQECYRYPIVLGYDSQHFVPLVTLKDSGPELRAVPLVNRDRGRFEDLKVHFLTDPENEMKEKLLKEYLIVMEIPVQGWDHGTTHLINAAKLDEANLPKEINLVDDYFELVQHEYKKWQENSDQARRAAHAQNPLEPSTPQLSLMDIKCETPNCPFFMSVNTQPLCHECSERRQKNQSKLPKLNSKLGPEG-LPGVGLGSSN--------WSPEETAGGPHSAPPTAPSLFLFSETTAMKCRSPGCPFTLNVQHNGFCERCH-ARQINAS-------HTAD------PGKCQACLQDVTRTFNGICSTCFKRTTAEPSSSLTSSIPASCHQRSKSDPSQLIQSLTPHSCHRTGNVSPSGCLSQAARTPGDRAGTSKCRKAGCMYFGTPENKGFCTLCFIEYRENKQSVTASEKAGSPAPR-FQNNVPCLGRECGTLGSTMFEGYCQKCFIEAQNQRFHEARRTEEQ---LRSSQHRDMPRTTQVASRLKCARASCKNILACRSEELCMECQHLSQRVGSVAHRGEPTPEEPPKQRCRAPACDHFGNAKCNGYCNECYQFKQMYG-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P21580-1", "uniprot_id": "TNAP3_HUMAN", "id": "P21580-1", "name": "Tumor necrosis factor alpha-induced protein 3", "aln": "--MAEQVLPQALYLSNMRKAVKIRERTPEDIFKPTNG--IIHHFKTMHRYTLEMFRTCQFCPQFREIIHKALIDRNIQATLESQKKLNWCREVRKLVALKTNGDGNCLMHATSQYMWGVQDTDLVLRKALFSTLKETDTRNFKFRWQLESLKSQEFVETGLCYDTRNWNDEWDNLIKMASTDTPMARSGLQYNSLEEIHIFVLCNILRRPIIVISDKMLRSLESGSNFAPLKVGGIYLPLHWPAQECYRYPIVLGYDSHHFVPLVTLKDSGPEIRAVPLVNRDRGRFEDLKVHFLTDPENEMKEKLLKEYLMVIEIPVQGWDHGTTHLINAAKLDEANLPKEINLVDDYFELVQHEYKKWQENSEQGRREGHAQNPMEPSVPQLSLMDVKCETPNCPFFMSVNTQPLCHECSERRQKNQNKLPKLNSKPGPEG-LPGMALGASRGEAYEPLAWNPEESTGGPHSAPPTAPSPFLFSETTAMKCRSPGCPFTLNVQHNGFCERCHNARQLHAS-------HAPDHTRHLDPGKCQACLQDVTRTFNGICSTCFKRTTAEASSSLSTSLPPSCHQRSKSDPSRLVRSPSPHSCHRAGNDAPAGCLSQAARTPGDRTGTSKCRKAGCVYFGTPENKGFCTLCFIEYRENKHFAAASGKVSPTASR-FQNTIPCLGRECGTLGSTMFEGYCQKCFIEAQNQRFHEAKRTEEQ---LRSSQRRDVPRTTQSTSRPKCARASCKNILACRSEELCMECQHPNQRMGPGAHRGEPAPEDPPKQRCRAPACDHFGNAKCNGYCNECFQFKQMYG-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7T672-1", "uniprot_id": "A0A8N7T672_DANRE", "id": "A0A8N7T672-1", "name": "ubiquitinyl hydrolase 1", "aln": "MSQGQNFLPKFLFVSNLLKAVKIRERVPNDVVKPSAGGSLIHHLRSMHRYTLEMIRMSQFPQAFREVIQAAILDRAMQSSLEQEKRLNWCREVKKLVPLRTNGDGNCLLHAASQYLLGVQDTDLVLRKALHAVLKETDTTDFLTRFQTELLHSQEFTQTGLRYSTLNWEEEWVKIVDMASPVS--SSNGLQFDSLEDIHIFVLSNILRRPIIVIADQVLRSMKSGSSFSPLNVGGIYLPLHWPPGECYKYPIVLGYDSQHFAPLITIKDSGPEIRAVPLINPGRGGFEELRVHFLTEKEQQQKEKLLKDFLMLIEIPVIGLGYDPTQIITAARLDEGNLPEDMNLMEDYLQLVNHEYKRWQEDKD-SLWAPQSQRPPPFSVSQLSLIEIRCATPRCTFYVSVDTQPHCHECFEKRQAGRK--PEAISTINQTSSSDTESRGKMER-----------SILPSPRSAPPTAPSLSLYSETHAMKCKTPGCLFTLSVEHDGLCERCFTARQNRTAGPSHGWWASGGRERERDTEKCVMCRQEVFRIFNGLCPPCMQRTAVSEREDTQQ------QQQQQQEP----RTEGSVWAERSG---------QTWQTPAAR----QCKRSGCQFFGTQEKLGFCTICYLDYQTNHQATPAIVQPRHTSEAGFQNCPRCRGPGCGAEGKAMLEGYCNKCFVKEQSARLNQAASRGSQSPPLVTRASKARP-PPPVLTQAQCRRSGCKNLSPG-CTDLCPDCLSRGQREG----RRAQAPKEKSKQRCKTQGCDHYANQEKQGYCNECDHFKQIYRG", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .::.**: *::**: ********.*:*:.**: * :*:*:::********:* .** ***:*: *::** :*::**.:*:*******:***.*:********:**:.**: ************* :.****** :* *:* * *:****.:*** *.* **::** :::.***. : : .***::***:******.**********:*::***::***.*:**:***********. ***:*********:**.**:*:******:*****:* ** **:*:*****: *:: ******::*:::**** * .:..*::*.**:***.***:::**::**::**:****:***: : . ::*.* *..****::::* **.*.*::**:*** **** *:** .:. *: *. . . . * . . .*:******** *:*** ****::*** ***.*:*:*:****. *** :: : . . ** * *:* * ***:*..*::**:.. .. :*:.:.:* :: . ..*:* *: :**. * :*:::** :*** *: ****:*:::*: *:: ..* : .: *** * * **: *.:*:****:***:: *. *:::* .* * : : * .. :: :* *:.***: . . :** :* .** . * :*:: .****:: .***:.* : :****** :***:* ", "identical_positions": 371, "similar_positions": 231, "identity": "45.97%" }, { "cls_id": "homologset.agr.MGI:1196378", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K0D2-1", "uniprot_id": "HABP2_MOUSE", "id": "Q8K0D2-1", "name": "Factor VII-activating protease", "aln": "MFVRMLVFR--VLLLIALVGKSVIGLSLMSFIAP--PDPDWTPDDYYYSYEQSSPDEDPSVTQTTPENPDWYYEDD--DPCQSNPCEHGGDCIIRGD-TFSCSCPAPFSGSRCQTAQNKCKDNPCVHGDCLITQKHPYYRCACKYPYTGPDCSKVLPACRPNPCQNGGVCSRHRRRSRFTCACPDQYKGKFCEIGPDDCYVGDGYSYRGKVSKTVNQNPCLYWNSHLLLQETYNMFMEDAETHGIAEHNFCRNPDGDHKPWCFVKVNSEKVKWEYCDVTVCPVPDTPNPVESLLEPVMELPGFESCGKTEVAEHAVKRIYGGFKSTAGKHPWQVSLQTSLPLTTSMPQGHFCGGALIHPCWVLTAAHCTDINTKHLKVVLGDQDLKKTESHEQTFRVEKILKYSQYNERDEIPHNDIALLKLKPVGGHCALESRYVKTVCLPSDPFPSGTECHISGWGVTETGEG-SRQLLDAKVKLIANPLCNSRQLYDHTIDDSMICAGNLQKPGSDTCQGDSGGPLTCEKDGTYYVYGIVSWGQECGKK--PGVYTQVTKFLNWIKTTMHREAGL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6L711-1", "uniprot_id": "HABP2_RAT", "id": "Q6L711-1", "name": "Factor VII-activating protease", "aln": "MSVVMLVFR--VLLLIALVGNSAIGLSLMPFIAP--PDPDWTPDDYYYSYEQSSPDKDASVTQTSPENPDWYYEDD--DPCQSNPCEHGGDCIIRGN-TFSCSCPAPFSGSRCQTVQNKCKDNPCVQGDCLITQTPPYYRCACKYPYTGPDCSKVLPVCRPNPCQNGGVCSRHRRRSRFSCACPDQYKGRFCEIGPDDCYVGDGYSYRGKVSRTVNQNPCLYWNSHLLLQENYNMFMEDAETHGIADHNFCRNPDGDHKPWCFVKVNSEKVKWEYCNVEVCPESDAANPVGSLQEPVMELPGFDSCGKTEMTEHAVKRIYGGFKSTAGKHPWQVSLQTSLPLTTSMPQGHFCGGSLIHPCWVLTAAHCTDMSTKHLKVVLGDQDLKKTESHEQTFRVEKILKYSQYNERDEIPHNDIALLKLKPVGGHCALESKYVKTVCLPSDPFPSGTECHISGWGVTETGEG-SRQLLDAKVKLIANALCNSRQLYDHTIDDSMICAGNLQKPGSDTCQGDSGGPLTCEKDGTYYVYGIVSWGQECGKK--PGVYTQVTKFLNWIKTTMHKEAGL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q14520-1", "uniprot_id": "HABP2_HUMAN", "id": "Q14520-1", "name": "Factor VII-activating protease", "aln": "MFARMSDLH--VLLLMALVGKTACGFSLMSLLES--LDPDWTPDQYDYSYEDYNQEENTSSTLTHAENPDWYYTEDQADPCQPNPCEHGGDCLVHGS-TFTCSCLAPFSGNKCQKVQNTCKDNPCGRGQCLITQSPPYYRCVCKHPYTGPSCSQVVPVCRPNPCQNGATCSRHKRRSKFTCACPDQFKGKFCEIGSDDCYVGDGYSYRGKMNRTVNQHACLYWNSHLLLQENYNMFMEDAETHGIGEHNFCRNPDADEKPWCFIKVTNDKVKWEYCDVSACSAQDVAYPEESPTEPSTKLPGFDSCGKTEIAERKIKRIYGGFKSTAGKHPWQASLQSSLPLTISMPQGHFCGGALIHPCWVLTAAHCTDIKTRHLKVVLGDQDLKKEEFHEQSFRVEKIFKYSHYNERDEIPHNDIALLKLKPVDGHCALESKYVKTVCLPDGSFPSGSECHISGWGVTETGKG-SRQLLDAKVKLIANTLCNSRQLYDHMIDDSMICAGNLQKPGQDTCQGDSGGPLTCEKDGTYYVYGIVSWGLECGKR--PGVYTQVTKFLNWIKATIKSESGF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QW52-1", "uniprot_id": "F1QW52_DANRE", "id": "F1QW52-1", "name": "trypsin", "aln": "MVVDWASFSPGIMFPVILLILGLSGLTSHVKAAPGLLEDFIGIVDEIYDYVVSDTEEISSAEIN--ETIDWLFSFFDEETCDPNPCQNNGVCKEKESGGFKCICPPPYIGKKCQNEKNVCKKVKCGNGDCVRIKKDPFYECKCWPPYRGSKCKNAY-ACNPSPCQNGGTCVKGRTRASFTCTCPEDYSGRFCQVGSNDCYEGNGESYRGNVSETIEEIECLPWNHNLIPYKEF----EGNES--IGEHNYCRNPDGDREPWCFVKEKG-KLQWNYCNVKPCSETEPEKPLTTPTK-----LEFSDCGKAAFSMIAP-RIFGGRKSLPEAHPWQASFQVR-PKGSNATFEHNCGGTLIDSCWILTAAHCIDEND-EVRVELGGVNLEKDDPDKQFVEVEKIIVHENYTETFDALYNDIALLKLKGRNGRCANESRSVRAACLPTDLFPEGTRCTISGYGATEKHHGVSTQLLDAKVLLISQSRCMSRNVYGNRMDDSMMCAGYMQG-KIDSCQGDSGGPLVCKKDNIHYIYGVVSWGDSCGKKNKPGVYARVTKFIDWINEKMRTA---", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . : ::: : *: *:: . : : *.* . :: .* . *. ** : :.*:.***::.* * : . *.* * .*: *.:**. :* **. * .*:*: :. *:*.* * ** *..*.:. .*.*.*****..* : : *: *:*:**:::.*:**::*.:*** *:* ****::..*::: ** ** :*: : : *. *: *.:**:*****.*.:****:* .. *::*:**:* *. : * : : *..***: .: **:** ** . ****.*:* * . . * ***:**..**:****** * . .::* **. :*:* : .:* ..****: :.:*.* : :********* .*:** **: *::.*** . **.*:.* ***:*.**. .* * ******* **::. * **::*.: :****:*** :* *:*********.*:**. :*:**:**** .***: ****::****::**: .:: ", "identical_positions": 219, "similar_positions": 174, "identity": "38.56%" }, { "cls_id": "homologset.agr.MGI:1196384", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5RJK0-1", "uniprot_id": "T106C_RAT", "id": "Q5RJK0-1", "name": "Transmembrane protein 106C", "aln": "MGSQHSSAL--TFCQRKKDDNPEDLLAERDQEEAIAQFPYVEFTGRNSITCHTCQGAGYIPEEQVNKLVALIPHSDQRLRPQRTKQYVLLSVLLCLLASGLVFFFLFPHSVLVDDNGIRVSNVTFNKQDSLVVLDVTATLKIRNSNFYPVAVTNLFSQVQYMKAVVGSYTAANVSLIPPRSEHLVNFTVKAEVGGPSSYVYFYCTLPAILVHNIVIFMRTSVQISYIGHTSQSTLEAQHNVDCGENSTAVQSLLLVPWGPHL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80VP8-1", "uniprot_id": "T106C_MOUSE", "id": "Q80VP8-1", "name": "Transmembrane protein 106C", "aln": "MGSQHSSAL--TFCQRKKDDNPEDLLADRDQEEAIAQFPYVEFTGRNSITCHTCQGAGYIPAEQVNELVALIPHSDQRLRPQRTKQYVLLSVLLCLLASGLVFFFLFPHSVLVDDNGIKVTKVTFNEQDSLVVLDVTATLKIRNSNFYPVAVTNLFSQVQYMKAVVGSYTTTNVSLIAPRSEHLVNFTVKAEVGGPSSYVYFYCTLPAIRVHNIVIFMRTSVKISYIGHISQSTLETQHYVDCGVNSTAAQSLFLVPRGPHL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BVX2-1", "uniprot_id": "T106C_HUMAN", "id": "Q9BVX2-1", "name": "Transmembrane protein 106C", "aln": "MGSQHSAAARPSSCRRKQEDDRDGLLAEREQEEAIAQFPYVEFTGRDSITCLTCQGTGYIPTEQVNELVALIPHSDQRLRPQRTKQYVLLSILLCLLASGLVVFFLFPHSVLVDDDGIKVVKVTFNKQDSLVILTIMATLKIRNSNFYTVAVTSLSSQIQYMNTVVSTYVTTNVSLIPPRSEQLVNFTGKAEMGGPFSYVYFFCTVPEILVHNIVIFMRTSVKISYIGLMTQSSLETHHYVDCGGNSTAI------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******:* : *:**::*: :.***:*:****************:**** ****:**** ****:************************:**********.************:**:* :****:*****:* : ***********.****.* **:***::**.:*.::*****.****:***** ***:*** *****:**:* * ************:***** :**:**::* **** **** ", "identical_positions": 189, "similar_positions": 41, "identity": "72.14%" }, { "cls_id": "homologset.agr.MGI:1196386", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D8K8-1", "uniprot_id": "S2539_MOUSE", "id": "Q9D8K8-1", "name": "Mitochondrial glutathione transporter SLC25A39", "aln": "MDDQ-------------------------------------------------------------------------------DPGGISPLQQMVASGAGAVVTSLFMTPLDVVKVRLQSQRPSATSELTTPSRFWSLSYTKSSSALQSPGKCLLYCNG---VLEPLYLCPNGTRCATWFQDPTRFTGTLDAFVKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGQ-------------------SLTSDLYAPMVAGALARMGTVTVVSPLELVRTKLQAQ---------HVSYRELASSVQAAVTQGG-WRSLWLGWGPTALRDVPFSALYWFNYELVKSWLSGLRPKDQTS------VGISFVAGGISGMVAATLTLPFDVVKTQRQMSLGAVEAVRVKPPR---VDSTWLLLRRIRAESGTRGLFAGFLPRIIKAAPSCAIMISTYEFGKSFFQRLNQEQPLGR-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4V8K4-1", "uniprot_id": "S2539_RAT", "id": "Q4V8K4-1", "name": "Mitochondrial glutathione transporter SLC25A39", "aln": "MDDQ-------------------------------------------------------------------------------DPGGISPLQQMVASGAGAVVTSLFMTPLDVVKVRLQSQRPTVASELTTPSRFWSLSYTKSPSTLQSPGKCLLYCNG---VLEPLYLCPNGTRCATWFQDPTRFTGTLDAFVKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGQ-------------------SLTSDLYAPMVAGALARMGTVTVVSPLELVRTKLQAQ---------HVSYRELAACVQAAVAQGG-WRSLWLGWGPTALRDVPFSALYWFNYELVKSQLNGPRQKEQTS------VGISFVAGGISGMVAATLTLPFDVVKTQRQMSLGAVEAMRVKPPR---VDSTWLLLRRIQAESGTRGLFAGFLPRIIKAAPSCAIMISTYEFGKSFFHRLNQEQPLGH-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BZJ4-1", "uniprot_id": "S2539_HUMAN", "id": "Q9BZJ4-1", "name": "Mitochondrial glutathione transporter SLC25A39", "aln": "MADQ-------------------------------------------------------------------------------DPAGISPLQQMVASGTGAVVTSLFMTPLDVVKVRLQSQRPSMASELMPSSRLWSLSYTKLPSSLQSTGKCLLYCNG---VLEPLYLCPNGARCATWFQDPTRFTGTMDAFVKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGR-------------------ALTSDLYAPMVAGALARLGTVTVISPLELMRTKLQAQ---------HVSYRELGACVRTAVAQGG-WRSLWLGWGPTALRDVPFSALYWFNYELVKSWLNGFRPKDQTS------VGMSFVAGGISGTVAAVLTLPFDVVKTQRQVALGAMEAVRVNPLH---VDSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMISTYEFGKSFFQRLNQDRLLGG-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7SXW0-1", "uniprot_id": "S2539_DANRE", "id": "Q7SXW0-1", "name": "Mitochondrial glutathione transporter SLC25A39", "aln": "MGDRPAV---------------------------------------------------------------------------RISAAITPVQQMLASGTGAVLTSLFVTPLDVVKIRLQAQQTPLFQAIAAESRPW-FRVTR-----PSKWKCFLYCNG---LMDHVYVCQNMSSCSNLYKTSTHFSGTLDAFVKITHNEGLRSLWSGLPPTLVMAVPATVIYFTCYDQLRDFLCYS-------------------MGYHGDHIPLIAGGLARLGAVSVISPLELVRTKMQSR---------RLQYSELMVCIRSSVAQDG-WLSLWRGWGPTVLRDVPFSALYWFNYELVKAQLCEHYRTPQAS------FTISFTAGAVSGAIAAVLTLPFDVVKTRRQIQLGEMEALGAVSMKK--PSSTWNMMRNIWIDMGYKGLFAGFLPRVIKVAPACAVMISTYEFGKTFFQERNLHQARCGL----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VWG0-1", "uniprot_id": "SHAWN_DROME", "id": "Q9VWG0-1", "name": "Solute carrier family 25 protein Shawn", "aln": "MATREACGQFAAASAAMAAAS---------------------------------------------------SQNPSKATMTDPRFRIRPLQQVASACTGAMVTACFMTPLDVIKTRLQAQQQALL-----------------------SNKCFLYCNG---LMDHICPCGPDTPNPAAAKPAPRFSGTIDAFIKISRTEGIGSLWSGLSPTLISALPSTIIYFVAYEQFKARFTDI---HYKYTRRPDTIAH-DIPHPIPFLVPLLAGVSGRILAVTCVSPVELIRTKMQSQ---------RMTHAEMFGTIRQVVQSQG-VLGLWRGLPPTILRDVPFSGIYWTCYEYLKSSFG----VVEPT------FSFSFAAGAISGSVAATITTPFDVVKTHEQIEFGEKFIFSDNPPKQVATKSVAMRLASIYRMGGVPAIFSGLGPRLFKVAPACAIMISSFEYGKSFFYHYNIDQHNRSNQATKGPGS--------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VI05-1", "uniprot_id": "Q9VI05_DROME", "id": "Q9VI05-1", "name": "Solute carrier family 25 member 40", "aln": "MSKEDSGASSAEANPAESEISMGRGPRPRSFTGGGGGGGTGGSGGSGGTSGGNNLKPERSAREDDAINRLTDSKSSHRKLLSDPRFQIRPLQQVISACTGAMITACFMTPLDVIKTRMQSQQSP-------------------------AHKCFFYSNG---LMDHLFASGPNGSELASLRQRPQFSSSWDALMKISRHEGLAALWSGLGPTLVSALPSTIIYFVAYEQFKARYLQIYESHYNKSQEPRHLEIRDTKKSLPSVVPMMSGVTARICAVTVVSPIELVRTKMQAQ---------RQTYAQMLQFVRSVVALQG-VWGLWRGLRPTILRDVPFSGIYWPIYESLKQNLGH---GSQPS------FSLSFLAGVMAGTVAAIVTTPFDVVKTHEQIEFGERVIFTDSPARDFGKKSTFSRLTGIYRTHGVRGLFAGCGPRLLKVAPACAIMISTFEYSKSFFFHYNVRHHNEALLLDNPKDTTVEDDDIE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53320-1", "uniprot_id": "MTM1_YEAST", "id": "P53320-1", "name": "Mitochondrial carrier protein MTM1", "aln": "MSDR------------------------------------------------------------------------------NTSNSLTLKERMLSAGAGSVLTSLILTPMDVVRIRLQQQQMIPDCSCDGAAEVPNAVSSG------SKMKTFTNVGGQNLNNAKIFWESACFQELHCKNSSLKFNGTLEAFTKIASVEGITSLWRGISLTLLMAIPANMVYFSGYEYIRDVSPIAS--------------------TYPTLNPLFCGAIARVFAATSIAPLELVKTKLQSIPRSSKSTKTWMMVKDLLNETRQEMKMVGPSRALFKGLEITLWRDVPFSAIYWSSYELCKERLWLDSTRFASKDANWVHFINSFASGCISGMIAAICTHPFDVGKTRWQISMMNNSDPKGGNRS----RNMFKFLETIWRTEGLAALYTGLAARVIKIRPSCAIMISSYEISKKVFGNKLHQ----------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . : ::: :: :*:::*: ::**:**:: *:* *: * : .* : . :*..: :*: ** ** :** *: **: ::*:. :** *: :: *:..* .*: :.: ::*:**::**:*: :: : : * .*: * * ******.:** ** * : .. . ** :* ::* :** * **** **: *: : . : * * .:::* .*::* *:**:***::* .*..* . ", "identical_positions": 79, "similar_positions": 91, "identity": "15.93%" }, { "cls_id": "homologset.agr.MGI:1196389", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QYV8-1", "uniprot_id": "DPOG1_RAT", "id": "Q9QYV8-1", "name": "DNA polymerase subunit gamma-1", "aln": "MSRLLWKKVAGAKVASGPVPATGRWVSSSVLDPVPSDGQ-----------------PQSQMPSSENGQLRLNPLHIQMLSRGLHEQIFG-CGGDVPDEAAVQRS---IEHLRKHGLWGQPTTPLPDVQLRLPRLFGGNLDQHFRLLAQKQSLPYLEAAASLSE-AQLPPQPRKWVWAEGWTRYGPE-GEAEPVAIPEERALVFDVEVCLAEGTCPTLAVAISPSAWYSWCSRRLVEERYSWTSQLSPADLIPLGVSASASSSTQ--------QDWQEQLVVGHNVSFDRAHIREQYLIQGSRMRFLDTMSMHMAISGLSSFQRSLWMGAKQGKHKTQHPTK-RGQKSQKNANGPAISSWDWMDISSANNLADVHNLYVGGPRLAKEPRELFVKGSMRDIRENFQDLMEYCARDVWATFEVFQQQLPLFLERCPHPVTLAGMLEMGVSYLPVNQN-WERYLTEAQSTYEELQREMKKSLMELANDACQLLSG-ERYKEDPWLWDLEWDLQEFKQKKAKKVKK-TASASKLPIEGAGPFGDPMDQEDPGPPSEEEELQQNIMAHTRLQQLKSTTDLLPKRPQHLPGHPGWYRKLCPR----------LDDPA-WTPGPSLLSLQMRVTPKLMALTWDGFPLHYSDSHGWGYLVPGRRDNLTELPVSPTEESAAVTCPYRAIESLYRRHCLDQGKQQLETQETDLAEEFLLTD-SAMWQTVEELGCLDVEAEATVE---SSGLSQPLVPPTACAPKTS--QPTYHHGNGPYNDVDIPGCWFFKLPHKDGNNYNVGSPFAKDFLPKMEDGTLQAG-PGGARGPRALEINKMISFWRNAHKRISSQMVVWLPRSA---LPRAVTRHPSFDEESHYGAILPQVVTAGTITRRAVEPTWLTASNARPDRVGSELKAMVQAPPGYVLVGADVDSQELWIAAVLGDAHFAGMHGCTAFGWMTLQGRKSRGTDLHSKTAATVGISREHAKVFNYGRIYGAGQSFAERLLMQFNHRLSRQEAADKAQQMYAVTKGLRRYRLSDDGEWLVKQLNVPVDRTEDGWVSLQDLRKIRREASR---KSRWKKWEVVTERAWTGGTESEMFNKLESIAMSDTPRTPVLGCCISRALEPS---VVQGEFMTSRVNWVVQSSAVDYLHLMLVAMKWLFEEFAIDGRFCISIHDEVRYLVREEDRYRAALALQITNLLTRCMFAYKLGLNDLPQSVAFFSAVDIDQCLRKEVTMDCKTPSNPTGMERKYGIPQGEALDIYQIIELTKGSLEKRSQPGP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P54099-1", "uniprot_id": "DPOG1_MOUSE", "id": "P54099-1", "name": "DNA polymerase subunit gamma-1", "aln": "MSRLLWKKVAGAKVASGPVPATARWVASSVLDPVPSDGR-----------------PPSQMPSSENGQLRLNPLLIQMLSRGLHEQIFG-CGGEMPDEAAVQRS---VEHLQKHGLWGQPATPLPDVELRLPRLFGGNLDQHFRLLAQKQSLPYLEAAASLLE-AQLPPEPKSWAWAEGWTRYGPE-GEAEPVAIPEERALVFDVEVCLAEGTCPTLAVAISPSAWYSWCSRRLVEERYSWTSQLSPADLIPLGGSTSASSSTK--------QDGQEQLVVGHNVSFDRAHIREQYLIQDSRMRFLDTMSMHMAISGLSSFQRSLWMGAKQGKHKNPAAHKARAEVPEESQWSSESSSWDWMDISSANNLADVHNLYVGGPPLEKEPRELFVKGSMRDIRENFQDLMQYCARDVWATFEVFQQQLPLFLERCPHPVTLAGMLEMGVSYLPVNQN-WERYLTEAQNTYEELQREMKKSLMDLANDACQLLSG-ERYKEDPWLWDLEWDLQEFKQKKAKKVKK-PASASKLPIEGAGPFGDPMDQEDPGPPSEEEELQRSVTAHNRLQQLRSTTDLLPKRPQHLPGHPGWYRQLCPR----------LDDPA-WAPGPSLLSLQMRVTPKLMALTWDGFPLHYSDSHGWGYLVPGRRDNLTEPPVSPTVESAAVTCPYRAIESLYRKHCLEQGKQQLEPQEVDLAEEFLLTDNSAMWQTVEELGCLDVEAEAKME---NSGLSQPLVLPAACAPKSS--QPTYHHGNGPYNDVNIPGCWFFKLPHKDGNNYNVGSPFAKDFLPKMEDGTLQAG-PGGASGPRALEINKMISFWRNAHKRISSQMVVWLPRSA---LPRVVTRHPAFDEEGHYGAILPQVVTAGTITRRAVEPTWLTASNARPDRVGSELKAMVQAPPGYVLVGADVDSQELWIAAVLGDAHFAGMHGCTAFGWMTLQGRKSRGTDLHSKTAATVGISREHAKIFNYGRIYGAGQSFAERLLMQFNHRLTRQEAAEKAQQMYAVTKGLRRYRLSADGEWLVKQLNLPVDRTEDGWVSLQDLRMIRREASR---KSRWKKWEVAAERAWTGGTESEMFNKLESIAMSDTPRTPVLGCCISRALEPS---VVQGEFITSRVNWVVQSSAVDYLHLMLVAMKWLFEEFAIDGRFCISIHDEVRYLVREEDRYRAALALQITNLLTRCMFAYKLGLNDLPQSVAFFSAVDIDQCLRKEVTMDCKTPSNPTGMERRYGIPQGEALDIYQIIELTKGSLEKRSQPGP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P54098-1", "uniprot_id": "DPOG1_HUMAN", "id": "P54098-1", "name": "DNA polymerase subunit gamma-1", "aln": "MSRLLWRKVAGATVGPGPVPAPGRWVSSSVPASDPSDGQRRRQQQQQQQQQQQQQPQQPQVLSSEGGQLRHNPLDIQMLSRGLHEQIFG-QGGEMPGEAAVRRS---VEHLQKHGLWGQPAVPLPDVELRLPPLYGDNLDQHFRLLAQKQSLPYLEAANLLLQ-AQLPPKPPAWAWAEGWTRYGPE-GEAVPVAIPEERALVFDVEVCLAEGTCPTLAVAISPSAWYSWCSQRLVEERYSWTSQLSPADLIPLEVPTGASSPTQ--------RDWQEQLVVGHNVSFDRAHIREQYLIQGSRMRFLDTMSMHMAISGLSSFQRSLWIAAKQGKHKVQPPTKQGQKSQRKARRGPAISSWDWLDISSVNSLAEVHRLYVGGPPLEKEPRELFVKGTMKDIRENFQDLMQYCAQDVWATHEVFQQQLPLFLERCPHPVTLAGMLEMGVSYLPVNQN-WERYLAEAQGTYEELQREMKKSLMDLANDACQLLSG-ERYKEDPWLWDLEWDLQEFKQKKAKKVKKEPATASKLPIEGAGAPGDPMDQEDLGPCSEEEEFQQDVMARACLQKLKGTTELLPKRPQHLPGHPGWYRKLCPR----------LDDPA-WTPGPSLLSLQMRVTPKLMALTWDGFPLHYSERHGWGYLVPGRRDNLAKLPTGTTLESAGVVCPYRAIESLYRKHCLEQGKQQLMPQEAGLAEEFLLTDNSAIWQTVEELDYLEVEAEAKMENLRAAVPGQPLALTARGGPKDT--QPSYHHGNGPYNDVDIPGCWFFKLPHKDGNSCNVGSPFAKDFLPKMEDGTLQAG-PGGASGPRALEINKMISFWRNAHKRISSQMVVWLPRSA---LPRAVIRHPDYDEEGLYGAILPQVVTAGTITRRAVEPTWLTASNARPDRVGSELKAMVQAPPGYTLVGADVDSQELWIAAVLGDAHFAGMHGCTAFGWMTLQGRKSRGTDLHSKTATTVGISREHAKIFNYGRIYGAGQPFAERLLMQFNHRLTQQEAAEKAQQMYAATKGLRWYRLSDEGEWLVRELNLPVDRTEGGWISLQDLRKVQRETAR---KSQWKKWEVVAERAWKGGTESEMFNKLESIATSDIPRTPVLGCCISRALEPS---AVQEEFMTSRVNWVVQSSAVDYLHLMLVAMKWLFEEFAIDGRFCISIHDEVRYLVREEDRYRAALALQITNLLTRCMFAYKLGLNDLPQSVAFFSAVDIDRCLRKEVTMDCKTPSNPTGMERRYGIPQGEALDIYQIIELTKGSLEKRSQPGP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F8W5R6-1", "uniprot_id": "F8W5R6_DANRE", "id": "F8W5R6-1", "name": "DNA polymerase subunit gamma-1", "aln": "MLRLISCHRWQTFVRSG---CWVRRCSTSVKSK-PQQGS---------------------------DQTRLNPLNIQMLSRNLQEQIFR-GQTQEYTDEDVERS---IRHLEHHGLWGKETSLLPDVQLRLPEMYGSNIDEHFRLLAQKQSLPYLEAASQLQK-AQIPEMPQEWAWEVGWTRYGAD-GESQKVNFPDENALVFDVEVCMAEGHCPTLAVALSPTAWYSWCSHRLVEDRYAWSSDLSLADLIPLETLANSSQPRG--------GEWKERLVVGHNVSFDRAHIKEQYLLKGSKMRFLDTMSLHMAISGLTGFQRSLWMASKYGKRKGLQEVKEHMKRLGRRPEGPKIGSWEWVNISSINNLADVHALYVGGDPLMKESRELFVKGSMSDIRGNFQELMQYCALDVLATQEVFTQQLPLFMERCPHPVTLAGMLEMGVCYLPVNHN-WRRYLEDAQATYEELQREMKKSLMILADDACQLLQD-DRYKDDPWLWDLDWDVQEFKQKKVPVSKK-KAKQEAEATEAANDSEAIDWPEDPGPPLEEEEGDSDP-RRELLQRLKETVSCLPKRRQHLPAHPSWYRKLCVK----------MSEAEDWSPGASLISLQMRITPKLMGLTWDGFPLHYTDQHGWGYLVPGRRDNLDIS-----EDNEEPVCPYRAIESVYKEYCEQKGKEQPKYPDSPVSDELMLTD-TAVWQTVEEVSRLEMFDDEALS---TAAPSKRITKKVNSVFKSLNGECPYHHGNGPYNDVNIPGCWFFKLPHKDGNENNVGSPFSKDFLSKMESGTLQAG-REGTNATRALEINKMISFWRNAQKRISSQMVVWLRRAE---LPRSVRLHQDYDEEGQYGAILPQVIPAGTVTRRAVEPTWLTASNARKDRVGSELKAMVQVPPAYHLVGADVDSQELWIAAMLGEAHFAGMHGCTAFGWMTLQGKKSQGTDLHSRTADAVGISREHAKVFNYGRIYGAGQPFAERLLMQFNHRLSQQEAAGKARQMYALTKGLRRYHLSEEGEWLLQKLNVNVERAEDGSISLQDLRKISKVATQSTTRGSKKKWNLTAGRVWTDGTESYMFNKLESIAQSDRPATPVLNCRISRALEPS---AVQEEFITSRVNWVVQSSAVDYLHLMLVSMRWLFEEHDIDGRFCISIHDEVRYLVTSEDRYRAALALQITNLLTRCMFAFKLGMMDLPQSVAFFSAVDIDKCLRKEVTMDCKTPSSPAGVERRYGLPQGEALDIYQIIEITKGSLTKEKRQAPRSK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q27607-1", "uniprot_id": "DPOG1_DROME", "id": "Q27607-1", "name": "DNA polymerase subunit gamma-1, mitochondrial", "aln": "-MQFHLIRKYASKVSREHYASSSVKIFRRVKPPQKVNKP-----------------KKPENVENGPTEYAENLVKVQMISRNLHAQLFP-QAPRSISEQQVASAKVYKDELRRHGVDIESSAPVSDVQLKLPALRGANIEEHFHNIAKEQVQPYEELLLPLVQCEQLPKRPKRWAFHTGWTAYDPEDGTATPVDHPLEKGLVFDVEVCVSEGQAPVLATAVSTKRWYSWVSSKLTKHR------LSVEKLEPLDVDTDSERPHYTTDELIPLGTTGPGLVVGHNVSYDRARLKEQYLTEDTGTRFVDTMSLHMCVSGVTSYQRAMLKSKKE----------------------PAAEDLGWLEQSSLNSLVEVHRLYCGGDTLSKEPRNIFVEGTLEQVRQSFQSLTNYCASDVEATHRILRVLYPLYAERFPHPASLAGMLEMGSAYLPVNSN-WERYIREAQLTYEDLSIEAKYHLGRRAEEACSLLLD-DQYRQNLWLWDEDWSVQELKLKQPPKRKP----------------LPTVELKDSGNTPEERR------LQAKFQHLYDQQALLPARRPLLPGYPLWYRKLCRKPPAKRADEILEDDEEPWSPGASEISTGMQIAPKLLSLCWEGYPLHYEREQGWGFLVPFRSD-------------SEGVDRLPMEQLLAHCPVPEFARLSASKAESDMAFDMLPGQVEQHLGKREHYKKLSQKQQRLET--------------------------QYQGSGVWCNKVLDDCCFFLKLPHKNGPSFRVGNPLSKDFLNKFAENVLSSGDPSCQAAARVIDIARMMSYWRNNRDRIMGQMVVWLDSQQ---LPNEFTGEKCQP--IAYGAICPQVVACGTLTRRAMEPTWMTASNSRPDRLGSELRSMVQAPPGYRLVGADVDSQELWIASVLGDAYACGEHGATPLGWMTLSGSKSNGSDMHSITAKAVGISRDHAKVINYARIYGAGQLFAETLLRQFNPTFSASEAKAKAMKMFSITKGKRVYRLREEFHDELEDR--AYSSYEASRLAIQRNRTLAEVFHR---------------PNWQGGTESAMFNRLEEIATGSQPRTPFLGGRLSRALEADTGPEQEQRFLPTRINWVVQSGAVDFLHLMLVSMRWLMGSH---VRFCLSFHDELRYLVKEELSPKAALAMHITNLMTRSFCVSRIGLQDLPMSVAFFSSVEVDTVLRKECTMDCKTPSNPHGLRIGYGIQPGQSLSVAEAIEKAGGNDVSQWDWIKKS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P15801-1", "uniprot_id": "DPOG_YEAST", "id": "P15801-1", "name": "DNA polymerase gamma", "aln": "MTKLMVRSECMLRMVRRRPLRVQFCARWFSTKKNTAEAP------------------------------RINPVGIQYLGESLQRQVFGSCGGKDEVEQSDKLMELSKKSLKDHGLWGKKTLITDPISFPLPPLQGRSLDEHFQKIGRFNSEPYKSFCEDKFT--EMVARPAEWLRKPGWVKYVPG-MAPVEVAYPDEELVVFDVETLYNVSDYPTLATALSSTAWYLWCSPFICGGD-------DPAALIPLNTLN------------------KEQVIIGHNVAYDRARVLEEYNFRDSKAFFLDTQSLHIASFGLCSRQRPMFMKNNKKK-------EAEVESEVHPEISIEDYDDPWLNVSALNSLKDVAKFHCKID-LDKTDRDFFASTDKSTIIENFQKLVNYCATDVTATSQVFDEIFPVFLKKCPHPVSFAGLKSLSKCILPTKLNDWNDYLNSSESLYQQSKVQIESKIVQIIKDIVLLKDKPDFYLKDPWLSQLDWTTKPLRLTKKG---------------------------------------------------------VPAKCQKLPGFPEWYRQLFPS----------------KDTVEPKITIKSRIIPILFKLSWENSPVIWSKESGWCFNVP------------------------------------------HEQVETYKAKNYVLADSVSQEEEEIRTHNLGLQCT----------------------------------------------GVLFKVPHPNGPTFNCTNLLTKSYNHFFEKGVLKSE---SELAHQALQINSSGSYWMSARERIQSQFVVPSCKFPNEFQSLSAKSSLNNEKTNDLAIIIPKIVPMGTITRRAVENAWLTASNAKANRIGSELKTQVKAPPGYCFVGADVDSEELWIASLVGDSIFN-VHGGTAIGWMCLEGTKNEGTDLHTKTAQILGCSRNEAKIFNYGRIYGAGAKFASQLLKRFNPSLTDEETKKIANKLYENTKG----------------------KTKRSKLFKK---------------------------FWYGGSESILFNKLESIAEQETPKTPVLGCGITYSLMKKN--LRANSFLPSRINWAIQSSGVDYLHLLCCSMEYIIKKYNLEARLCISIHDEIRFLVSEKDKYRAAMALQISNIWTRAMFCQQMGINELPQNCAFFSQVDIDSVIRKEVNMDCITPSN------KTAIPHGEALDINQLLDKSNSKLGKPNLDIDSKVSQYAYNYREPVFEEYNKSYTPEFLKYFLAMQVQSDKRDVNRLEDEYLRECTSKEYARDGNTAEYSLLDYIKDVEKGKRTKVRIMGSNFLDGTKNAKADQRIRLPVNMPDYPTLHKIANDSAIPEKQLLENRRKKENRIDDENKKKLTRKKNTTPMERKYKRVYGGRKAFEAFYECANKPLDYTLETEKQFFNIPIDGVIDDVLNDKSNYKKKPSQARTASSSPIRKTAKAVHSKKLPARKSSTTNRNLVELERDITISREY", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : : * : :* :...*: *:* : *. **: : : :.: ** : * .:::**: :.: : ** . :: * * **. * . . * * *. :*****. . *.**.*:*.. ** * * : . * ** :::****::***:: *:* ..: *:** *:*:. *: . **.: : . *:: *: *.* :* :: * * *::*.. : .**.* :*** ** ** .:: *:: :: ***.::**: .:. . **.: * *. *: .:: *:: . : : : .: * : * .: ** : :* : :: .: :* : **..* ***:* . . :: :: * *: * *:. *: : ** : ** : : : : : . * ::*:** :* . . ::*.: : ...*.: . :.::* *:* . :.** .*:** . . * *:::. **:****:* :*:****:: :*:****:: *:.**.* :*******:*****:::*:: ** *.:*** *.* *..*:*:*: ** :* **:.**::**.****** **. ** :** :: .*: * ::: *** : . : : * .*:** :**:**.** . * **.*. :: :* . *:.:*:**.:**..**:***: :*.::: .. *:*:*:***:*:** .: :**:*::*:*: **.: ::*: :** . **** *::* :*** .*** ***. .: *::*.: : :: : .. . ", "identical_positions": 262, "similar_positions": 293, "identity": "16.99%" }, { "cls_id": "homologset.agr.MGI:1196391", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3Z8X4-1", "uniprot_id": "D3Z8X4_RAT", "id": "D3Z8X4-1", "name": "DNA polymerase epsilon catalytic subunit", "aln": "-MVLRNSGRRHPEPGADSEGSRDDGPSS-SVSALKRLERSQWTDKMDLRFGFERLKEPGE--------------RTGWLINMHPTEILDE-------------------DKRLVSAVDYYFIQDDGSRFKVALPYKPYFYIAARKGCDR-EVSSFLSKKFQGKIAKLENVPKEDLDLPNHLVGLKRSYIKLSFHTVEDLVKVRKEISPAVKKNREQDHASDEYTTMLSSILQGGSLITDEEETSKKIADQLDNIVDMREYDVPYHIRLSIDLRIHVAHWYNVRFRGNAFPVEIARRDDLVERPDPVVLAFDIETTKLPLKFPDAETDQIMMISYMIDGQGYLITNREIVSEDIEDFEFTPKPEYEGPFCVFNEPDEVHLIQRWFEHIQETKPTIMVTYNGDFFDWPFVEARAAIHGLSMYQEIGFQKDSQGEYKAPQCIHMDCLRWVKRDSYLPVGSHNLKAAAKAKLGYDPVELDPEDMCRMATEQPQTLATYSVSDAVATYYLYMKYVHPFIFALCTIIPMEPDEVLRKGSGTLCEALLMVQAFHANIIFPNKQEQEFNKLTDDGHVLDAETYVGGHVEALESGVFRSDIPCRFRMNPAAFDFLLQRVEKTMRHAIEEEEKVPVEQATNFQEVCEQIKTKLTSLKDVPNRIECPLIYHLDVGAMYPNIILTNRLQPSAIVDEATCAACDFNKPGATCQRKMAWQWRGEFMPASRSEYHRIQHQLESEKFPP--LFPEGPARAFHELSREEQAKYEKRRLADYCRKAYKKIHMTKVEERLTTICQRENSFYVDTVRAFRDRRYEFKGLHKVWKKKLSAAVEVGDASEVKRCKNMEILYDSLQLAHKCILNSFYGYVMRKGARWYSMEMAGIVCFTGANIITQARELIEQIGRPLELDTDGIWCVLPNSFPENFVIKTTNVKKPKLTISYPGAMLNIMVKEGFTNHQYQELTEPSS---LTYVTRSENSIFFEVDGPYLAMILPASKEEGKKLKKRYAVFNEDGSLAELKGFEVKRRGELQLIKIFQSSVFEAFLKGSTLEEVYASVAKVADYWLDVLYSKAANMPDSELFELISENRSMSRKLEDYGEQKSTSISTAKRLAEFLGDQMVKDAGLSCRYIISRKPEGSPVTERAIPLAIFQAEPTVRKHFLRKWLKSSSLQDFDIRTILDWDYYIERLGSAIQKIITIPAALQQVKNPVPRVKHPDWLHKKLLEKNDIYKQKKISELFVLEGKRQIVMAQASENSLSLCTPDMEDFGLTKPYHSTV--PVATKRKR-VWESQKESQDITLTVPWQEVLGQPPSLGTTQEEWLVWLQFHKKKWQLQAQQRLARRKKQRLESAEDMPRLGAIREGPATGLGSFLRRTARSIMDLPWQIIQISETRQAGLFRLWAIIGSDLHCIKLSIPRVFYVNQR-VAKAEDGPS---YRKVNRALPRSNIVYN-----LYEYSVPEDMYQEHINEINTELSAPDIEGVYETQVPLLFRALVQLGCVCVVNKQLAR---QLSGWEAETFALEHLEMRSLAQFSYLEPGS--IRHIYLYHH--TQGHKALFGVFIPSQRRASVFVLDTVRSNQMP---GLSALYSAEHSLLLDKVGP---NLLPPPKHTFEVRAETNLKTICRAIQRFLLAYKEERRGPTLIAIQSSWELCRLTSEIPVLEEFPLVPVRVADKIS-YAVLDWQRHGARRMIRHYLNLDICLSQAFEMSRYFHIPVGNLPEDISTFGSDLFFARHLQRHNHLLWLSPTS-RPDLGGKEAD-DNRLVMEFDDRATVEINNSGCYSTVCVELDIQNLAVNTILQSHHVNDMEGAGSMGISFDVIQQASLEDMVTGNQAASALASYDETALCSSTFRILKSMVVGWVKEITQYHNIYADNQVMHFYRWLQSPCSLLHDPALHRTLHNMMKKLFLQLIAEFKRLGSSVIYANFNRIILCTKKRRIEDALAYVEYITNSIHSKEIFHSLTISFSRCWEFLLWMDPSNYGGIKGKVP-------SSIHCGQVREQDSQTREETEDEEDNEK--DEEEEEDMGQSEVEDL-LENNWNILQFLPQAASCQSYFLMIVSAYIVAVYQSMKDELRHSAPGSTPVKRKGASQFSQEAEGAAGALPGMITFSQDYVANELTQTFFTITQKIQKKVT--GSRNTAEPSEMFPVLPGSHLLLNNPALEFIKYVCKVLSLDTNITNQVNKLNRDLLRLVDVGEFSEEAQFRDPCHSYVLPEVICHSCNFCRDLDLCKDSSFSQDGAILPQWLCSNCQAPYDSSAIESALVEALQRKLMAFTLQDLVCLKCRGMKETHMPVYCGCAGDFVLTIHTEVFMEQIRIFQNIAKYYNMSYLQEAIEWLLQTSPVSNF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WVF7-1", "uniprot_id": "DPOE1_MOUSE", "id": "Q9WVF7-1", "name": "DNA polymerase epsilon catalytic subunit A", "aln": "-MVLRNSGRRHPEPGADGEGSRDDGPSS-SVSALKRLERSQWTDKMDLRFGFERLKEPGE--------------RTGWLINMHPTEILDE-------------------DKRLVSAVDYYFIQDDGSRFKVALPYMPYFYIAARKGCDR-EVSSFLSKKFQGKIAKLENVPKEDLDLPNHLVGLKRSYIKLSFHTVEDLVKVRKEISPAVKKNREQDHASDEYTTMLSSILQGGSVITDEDETSKKIADQLDNIVDMREYDVPYHIRLSIDLRIHVAHWYNVRFRGNAFPVEITRRDDLVERPDPVVLAFDIETTKLPLKFPDAETDQIMMISYMIDGQGYLITNREIVSEDIEDFEFTPKPEYEGPFCVFNEPDEVHLIQRWFEHIQETKPTIMVTYNGDFFDWPFVEARAAIHGLSMYQEIGFQKDSQGEYKAPQCIHMDCLRWVKRDSYLPVGSHNLKAAAKAKLGYDPVELDPEDMCRMATEQPQTLATYSVSDAVATYYLYMKYVHPFIFALCTIIPMEPDEVLRKGSGTLCEALLMVQAFHANIIFPNKQEQEFNKLTDDGHMLDAETYVGGHVEALESGVFRSDIPCRFRMNPAAFDFLLQRVEKTMRHAIEEEEKVPVEQATNFQEVCEQIKTKLTSLKDVPNRIECPLIYHLDVGAMYPNIILTNRLQPSAIVDEATCAACDFNKPGASCQRKMAWQWRGEFMPASRSEYHRIQHQLESEKFPP--LFPEGPARAFHELSREEQAKYEKRRLADYCRKAYKKIHVTKVEERLTTICQRENSFYVDTVRAFRDRRYEFKGLHKVWKKKLSAAVEVGDASEVKRCKNMEILYDSLQLAHKCILNSFYGYVMRKGARWYSMEMAGIVCFTGANIITQARELIEQIGRPLELDTDGIWCVLPNSFPENFVIKTTNAKKPKLTISYPGAMLNIMVKEGFTNHQYQELTEPSS---LTYVTHSENSIFFEVDGPYLAMILPASKEEGKKLKKRYAVFNEDGSLAELKGFEVKRRGELQLIKIFQSSVFEAFLKGSTLEEVYGSVAKVADYWLDVLYSKAANMPDSELFELISENRSMSRKLEDYGEQKSTSISTAKRLAEFLGDQMVKDAGLSCRYIISRKPEGSPVTERAIPLAIFQAEPTVRKHFLRKWLKSSSLQDFDIRTILDWDYYIERLGSAIQKIITIPAALQQVKNPVPRVKHPDWLHKKLLEKNDIYKQKKISELFVLEGKRQIVMAQASENSLSLCTPDMEDIGLTKPHHSTV--PVATKRKR-VWETQKESQDIALTVPWQEVLGQPPSLGTTQEEWLVWLQFHKKKWQLQAQQRLALRKKQRLESAEDMPRLGPIREGPSTGLGSFLRRTARSIMDLPWQIIQISETRQAGLFRLWAIIGNDLHCIKLSIPRVFYVNQR-VAKAEDGPA---YRKVNRALPRSNIVYN-----LYEYSVPEDMYQEHINEINTELSVPDIEGVYETQVPLLFRALVQLGCVCVVNKQLTR---HLSGWEAETFALEHLEMRSLAQFSYLEPGS--IRHIYLYHH--TQGHKALFGVFIPSQRRASVFVLDTVRSNQMP---GLSALYSSEHSLLLDKVDP---KLLPPPKHTFEVRAETNLKTICRAIQRFLLAYKEERRGPTLIAVQSSWELCRLTSEIPVLEEFPLVPIRVADKIS-YAVLDWQRHGARRMIRHYLNLDLCLSQAFEMSRYFHIPVGNLPEDISTFGSDLFFARHLQHHNHLLWLSPTS-RPDLGGKEAD-DNRLVMEFDDRATVEINSSGCYSTVCVELDIQNLAVNTILQSHHVNDMEGAGSMGISFDVIQQASLEDMVTGNQAASALANYDETALCSSTFRILKSMVVGWVKEITQYHNIYADNQVMHFYRWLQSPCSLLHDPALHRTLHNMMKKLFLQLIAEFKRLGSSVVYANFNRIILCTKKRRIEDALAYVEYITNSIHSKEIFHSLTISFSRCWEFLLWMDPSNYGGIKGKVP-------SSIHCGQVKEQDSQAREETDEEEEDKE--KDEEEEGMGESEVEDL-LENNWNILQFLPQAASCQSYFLMIVSAYIVAVYQSMKEELRHSAPGSTPVKRKGASQFSQESEGATGSLPGMITFSQDYVANELTQSFFTITQKIQKKVT--GSRNTTEPSEMFPVLPGSHLLLNNPALEFIKYVCKVLSLDTNITNQVNKLNRDLLRLVDVGEFSEEAQFRDPCHSYVLPEVICHSCNFCRDLDLCKDSSFSQDGAILPQWLCSNCQAPYDSSAIESALVEALQRKLMAFTLQDLVCLKCRGMKETHMPVYCSCAGDFTLTIRTEVFMEQIRIFQNIAKYYSMSYLQETIEWLLQTSPVSNC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q07864-1", "uniprot_id": "DPOE1_HUMAN", "id": "Q07864-1", "name": "DNA polymerase epsilon catalytic subunit A", "aln": "-MSLRSGGRRRADPGADGEASRDDGATS-SVSALKRLERSQWTDKMDLRFGFERLKEPGE--------------KTGWLINMHPTEILDE-------------------DKRLGSAVDYYFIQDDGSRFKVALPYKPYFYIATRKGCER-EVSSFLSKKFQGKIAKVETVPKEDLDLPNHLVGLKRNYIRLSFHTVEDLVKVRKEISPAVKKNREQDHASDAYTALLSSVLQRGGVITDEEETSKKIADQLDNIVDMREYDVPYHIRLSIDLKIHVAHWYNVRYRGNAFPVEITRRDDLVERPDPVVLAFDIETTKLPLKFPDAETDQIMMISYMIDGQGYLITNREIVSEDIEDFEFTPKPEYEGPFCVFNEPDEAHLIQRWFEHVQETKPTIMVTYNGDFFDWPFVEARAAVHGLSMQQEIGFQKDSQGEYKAPQCIHMDCLRWVKRDSYLPVGSHNLKAAAKAKLGYDPVELDPEDMCRMATEQPQTLATYSVSDAVATYYLYMKYVHPFIFALCTIIPMEPDEVLRKGSGTLCEALLMVQAFHANIIFPNKQEQEFNKLTDDGHVLDSETYVGGHVEALESGVFRSDIPCRFRMNPAAFDFLLQRVEKTLRHALEEEEKVPVEQVTNFEEVCDEIKSKLASLKDVPSRIECPLIYHLDVGAMYPNIILTNRLQPSAMVDEATCAACDFNKPGANCQRKMAWQWRGEFMPASRSEYHRIQHQLESEKFPP--LFPEGPARAFHELSREEQAKYEKRRLADYCRKAYKKIHITKVEERLTTICQRENSFYVDTVRAFRDRRYEFKGLHKVWKKKLSAAVEVGDAAEVKRCKNMEVLYDSLQLAHKCILNSFYGYVMRKGARWYSMEMAGIVCFTGANIITQARELIEQIGRPLELDTDGIWCVLPNSFPENFVFKTTNVKKPKVTISYPGAMLNIMVKEGFTNDQYQELAEPSS---LTYVTRSENSIFFEVDGPYLAMILPASKEEGKKLKKRYAVFNEDGSLAELKGFEVKRRGELQLIKIFQSSVFEAFLKGSTLEEVYGSVAKVADYWLDVLYSKAANMPDSELFELISENRSMSRKLEDYGEQKSTSISTAKRLAEFLGDQMVKDAGLSCRYIISRKPEGSPVTERAIPLAIFQAEPTVRKHFLRKWLKSSSLQDFDIRAILDWDYYIERLGSAIQKIITIPAALQQVKNPVPRVKHPDWLHKKLLEKNDVYKQKKISELFTLEGRRQVTMAEASEDSPRPSAPDMEDFGLVKLPHPAA--PVTVKRKRVLWESQEESQDLTPTVPWQEILGQPPALGTSQEEWLVWLRFHKKKWQLQARQRLARRKRQRLESAEGVLRPGAIRDGPATGLGSFLRRTARSILDLPWQIVQISETSQAGLFRLWALVGSDLHCIRLSIPRVFYVNQR-VAKAEEGAS---YRKVNRVLPRSNMVYN-----LYEYSVPEDMYQEHINEINAELSAPDIEGVYETQVPLLFRALVHLGCVCVVNKQLVR---HLSGWEAETFALEHLEMRSLAQFSYLEPGS--IRHIYLYHH--AQAHKALFGIFIPSQRRASVFVLDTVRSNQMP---SLGALYSAEHGLLLEKVGP---ELLPPPKHTFEVRAETDLKTICRAIQRFLLAYKEERRGPTLIAVQSSWELKRLASEIPVLEEFPLVPICVADKIN-YGVLDWQRHGARRMIRHYLNLDTCLSQAFEMSRYFHIPIGNLPEDISTFGSDLFFARHLQRHNHLLWLSPTA-RPDLGGKEAD-DNCLVMEFDDQATVEINSSGCYSTVCVELDLQNLAVNTILQSHHVNDMEGADSMGISFDVIQQASLEDMITGGQAASAPASYDETALCSNTFRILKSMVVGWVKEITQYHNIYADNQVMHFYRWLRSPSSLLHDPALHRTLHNMMKKLFLQLIAEFKRLGSSVIYANFNRIILCTKKRRVEDAIAYVEYITSSIHSKETFHSLTISFSRCWEFLLWMDPSNYGGIKGKVS-------SRIHCGLQDSQKAGGAEDEQENEDDEEERDGEEEEEAEESNVEDL-LENNWNILQFLPQAASCQNYFLMIVSAYIVAVYHCMKDGLRRSAPGSTPVRRRGASQLSQEAEGAVGALPGMITFSQDYVANELTQSFFTITQKIQKKVT--GSRNSTELSEMFPVLPGSHLLLNNPALEFIKYVCKVLSLDTNITNQVNKLNRDLLRLVDVGEFSEEAQFRDPCRSYVLPEVICRSCNFCRDLDLCKDSSFSEDGAVLPQWLCSNCQAPYDSSAIEMTLVEVLQKKLMAFTLQDLVCLKCRGVKETSMPVYCSCAGDFALTIHTQVFMEQIGIFRNIAQHYGMSYLLETLEWLLQKNPQLGH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VCN1-1", "uniprot_id": "DPOE1_DROME", "id": "Q9VCN1-1", "name": "DNA polymerase epsilon catalytic subunit 1", "aln": "-MSDSSKGKVLQNTGKFVSENRTEGDDF-FNEAGYRQSRE--NDKIDSKYGFDRVKDSQE--------------RTGYLINMHSNEVLDE-------------------DRRLIAALDLFFIQMDGSRFKCTVAYQPYLLIRPEDNMHL-EVARFLGRKYSGQISGLEHITKEDLDLPNHLSGLQQQYIKLSFLNQTAMTKVRRELMSAVKRNQERQKSNTYYMQMLATSLAQSSAGSEDATLGKRQQDYMDCIVDIREHDVPYHVRVSIDLRIFCGQWYNIRCRSGVELPTITCRPDILDRPEPVVLAFDIETTKLPLKFPDAQTDQVMMISYMIDGQGYLITNREIISSNVDDFEYTPKPEFEGNFIVFNEENEMQLLQRFFDHIMEVRPHIIVTYNGDFFDWPFVETRAAVYDLDMKQEIGFSKLRDGNYLSRPAIHMDCLCWVKRDSYLPVGSQGLKAVAKAKLRYDPVELDPEDMCRMAVEQPQVLANYSVSDAVATYYLYMKYVHPFIFALNTIIPMEPDEILRKGSGTLCETLLMVEAYHAQIVYPNKHQSELNKLSNEGHVLDSETYVGGHVEALESGVFRADIPCRFRLDPAMVKQLQEQVDAVLRHAIEVEEGIPLEKVLNLDEVRQEIVQGLQGLHDIPNRLEQPVIYHLDVGAMYPNIILTNRLQPSAMVSDLDCAACDFNKPGVRCKRSMDWLWRGEMLPASRNEFQRIQQQLETEKFPP--LFPGGPQRAFHELSKEDQAAYEKKRLTDYCRKAYKKTKLTKLETRTSTICQKENSFYVDTVRAFRDRRYEYKGLTKVAKASVNAAVASGDAAEIKAAKGREVLYDSLQLAHKCILNSFYGYVMRRGARWHSMPMAGIVCLTGSNIITKAREIIERVGRPLELDTDGIWCILPGSFPQEFTIHTSHEKKKKINISYPNAVLNTMVKDHFTNDQYHELRKDKENNLPKYDIRDENSIFFEVDGPYLAMVLPAAKEEGKKLKKRYAVFNFDGTLAELKGFEVKRRGELQLIKNFQSSVFEAFLAGSTLEECYASVAKVADYWLDVLYSRGSNLPDSELFELISENKSMSKKLEEYGAQKSTSISTAKRLAEFLGEQMVKDAGLACKYIISKKPEGAPVTERAIPLAIFQSEPSVRRHHLRRWLKDNTMGDADIRDVLDWNYYIERLGGTIQKIITIPAALQGLANPVPRVQHPDWLHKKMLEKNDVLKQRRINEMFTSRPKPKPLATEEDK------LADMEDLAGKDGGEGAAGCPIVTKRKRIQLEEHDDEEAQPQATTWRQALGAPPPIGETRKTIVEWVRFQKKKWKWQQDQRQRNRQASKRTRGEDPPVVRAT--GSTATLGGFLRRAQRTLLDQPWQIVQLVPVDDLGHFTVWALIGEELHKIKLTVPRIFYVNQRSAAPPEEGQL---WRKVNRVLPRSRPVFN-----LYRYSVPEQLFRDNSLGMLADLATPDIEGIYETQMTLEFRALMDMGCICGVQREEARRLAQLATKDLETFSIEQLEQRPQTQVKYLASANNRLRKIYLYQHNTPTAKKEIWSLILMPSKKAFVFALDTVRANQMP---NMRQLYTAERLALLKNLTAEEQDKIPVEDYTFEVLIEVDVKQIYRHIQRALTTYKQEHQGPTILCLQTALSARKLSLAMPILLEFPQAEIHISDDASLLSGLDWQRQGSRAVIRHFLNLNNVLDLMLDQCRYFHVPIGNMPPDTVLFGADLFFARLLQRHNFVLWWSAST-RPDLGGREAD-DSRLLAEFEESISVVQNKAGFYPDVCVELALDSLAVSALLQSTRIQEMEGASSA-ITFDVMPQVSLEEMIG-TVPAATLPSYDETALCSAAFRVMRSMVNGWLREVSINRNIFSDFQIVHFYRWVRSSNALLYDPALRRSLNNLMRKMFLRIIAEFKRLGATIIYADFNRIILSSGKKTVSDALGYVDYIVQSLRNKEMFHSIQLSFEQCWNFMLWMDQANFSGIRGKLPKGIDETVSSIVSTTMIRDSERNQDDDEDEEEDSENRDPVESNEAEQDQEDELSLELNWTIGEHLPDENECREKFESLLTLFMQSLAEKKTTEQ---------------------------------------AIKDISHCAFDFILKLHKNYG--KGKP-------------------SPGLELIRTLIKALSVDKTLAEQINELRRNMLRLVGIGEFSDLAEWEDPCDSHIINEVICKACNHCRDLDLCKDKHRAMKDG-VPVWLCAQCYVAYDNEEIEMRMLDALQRKMMSYVLQDLRCSRCSEIKRENLAEFCTCAGNFVPLISGKDIQTLLGTFNKVAANHKMQLLQQTVHQALTTPR----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P21951-1", "uniprot_id": "DPOE_YEAST", "id": "P21951-1", "name": "DNA polymerase epsilon catalytic subunit A", "aln": "MMFGKKKNNGGSSTARYSAGNKYNTLSNNYALSAQQLLNASKIDDIDSMMGFERYVPPQYNGRFDAKDIDQIPGRVGWLTNMHATLVSQETLSSGSNGGGNSNDGERVTTNQGISGVDFYFLDEEGGSFKSTVVYDPYFFIACNDESRVNDVEELVKKYLESCLKSLQIIRKEDLTMDNHLLGLQKTLIKLSFVNSNQLFEARKLLRPILQDNANNNVQRNIYNVAAN---------------GSEKVDAKHLIEDIREYDVPYHVRVSIDKDIRVGKWYKVTQQG------FIEDTRKIAFADPVVMAFDIETTKPPLKFPDSAVDQIMMISYMIDGEGFLITNREIISEDIEDFEYTPKPEYPGFFTIFNENDEVALLQRFFEHIRDVRPTVISTFNGDFFDWPFIHNRSKIHGLDMFDEIGFAPDAEGEYKSSYCSHMDCFRWVKRDSYLPQGSQGLKAVTQSKLGYNPIELDPELMTPYAFEKPQHLSEYSVSDAVATYYLYMKYVHPFIFSLCTIIPLNPDETLRKGTGTLCEMLLMVQAYQHNILLPNKHTDPIERFYD-GHLLESETYVGGHVESLEAGVFRSDLKNEFKIDPSAIDELLQELPEALKFSVEVENKSSVDKVTNFEEIKNQITQKLLELKENNIRNELPLIYHVDVASMYPNIMTTNRLQPDSIKAERDCASCDFNRPGKTCARKLKWAWRGEFFPSKMDEYNMIKRALQNETFPNKNKFSKKKVLTFDELSYADQVIHIKKRLTEYSRKVYHRVKVSEIVEREAIVCQRENPFYVDTVKSFRDRRYEFKGLAKTWKGNLS-KIDPSDKHARDEAKKMIVLYDSLQLAHKVILNSFYGYVMRKGSRWYSMEMAGITCLTGATIIQMARALVERVGRPLELDTDGIWCILPKSFPETYFFTLENGK--KLYLSYPCSMLNYRVHQKFTNHQYQELKDPLN---YIYETHSENTIFFEVDGPYKAMILPSSKEEGKGIKKRYAVFNEDGSLAELKGFELKRRGELQLIKNFQSDIFKVFLEGDTLEGCYSAVASVCNRWLDVLDSHGLMLEDEDLVSLICENRSMSKTLKEYEGQKSTSITTARRLGDFLGEDMVKDKGLQCKYIISSKPFNAPVTERAIPVAIFSADIPIKRSFLRRWTLDPSLEDLDIRTIIDWGYYRERLGSAIQKIITIPAALQGVSNPVPRVEHPDWLKRKIATKEDKFKQTSLTKFFS-KTKNVPTMG---------KIKDIEDLFEPTVEEDNAKIKIARTTKKKAVSKRKRNQ----LTNEEDPLVLPSEIPSMDEDYVGWLNYQKIKWKIQARDRKRRDQLFGNTNSS----------RERSALGSMIRKQAESYANSTWEVLQYKDSGEPGVLEVFVTINGKVQNITFHIPKTIYMKFKSQTMPLQKIKNCLIEKSSASLPNNPKTSNPAGGQLFKITLPESVFLEEKENCTSIFNDENVLGVFEGTITPHQRAIMDLGASVTFRSKAMG---ALGKGIQQGFEMKDLSMAE--NERYLSGFS--MDIGYLLHFP-TSIGYEFFSLFKSWGDTITILVLKPSNQAQEINASSLGQIYKQMFEKKKGKIETYSYLVDIKEDINFEFVYFTDISKLYRRLSQETTKLKEERGLQFLLLLQSPFITKLLG-TIRLLNQMPIVKLSLNEVLL--PQLNWQPTLLKKLVNHVLSSGSWISHLIKLSQYSNIPICNLRLDSMDYIIDVLYARKLKKENIVLWWNEKAPLPDHGGIQNDFDLNTSWIMNDSEFPKINNSGVYDNVVLDVGVDNLTVNTILTSALINDAEGSDLVNNNMGIDDKD---------AVINSPSEFVHDAFSNDALNVLRGMLKEWWDEALK-ENSTADLLVNSLASWVQNPNAKLFDGLLRYHVHNLTKKALLQLVNEFSALGSTIVYADRNQILIKTNKYSPENCYAYSQYMMKAVRTNPMFSYLDLNIKRYWDLLIWMDKFNFSGLA------------------CIEIEEKENQDYTAVSQWQLKKFLSPIYQPEFEDWMMIILDSMLKTKQSYLKLNSGTQRPTQIVNVKKQDKEDSVENSLNG-------------------------------------FSHLFSKPLMKRVKKLFKNQQEFILDPQYEADYVIPVLPGSHLNVKNPLLELVKSLCHVMLLSKSTILEIRTLRKELLKIFELREFAKVAEFKDPSLSLVVPDFLCEYCFFISDIDFCKAAPES-------IFSCVRCHKAFNQVLLQEHLIQKLRSDIESYLIQDLRCSRCHKVKRDYMSAHCPCAGAWEGTLPRESIVQKLNVFKQVAKYYGFDILLSCIADLTI-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . .. ... .: : : : . *.:* **:* . :.*:* ***.. : :* .: :.:* :*:: :*. ** :: * **: * .. :* :: : .. : :: : **** : *** **:: *:*** . : :.*: : . :: * :.: * ... * . * *:**:*****:*:*** * .:**:: :. : : .:***:******** ******: .**:*********:*:*******:*.:::***:*****: * * :*** :* *:**:*:*: :.:* :: *:*********:. *: ::.*.* :**** :*:* : . ****: ********* **:.***.:::** *:*:***** * * *:** *: **********************:* ****::*** ****:***** ****:*:: :*: ***: . :::: : **:*::*********:**:****:*: .*:::*: .. * :.: .::.::* *: .:::. *::*: ::* * *:: * * *:***:**.:*****: ******.:: : **:****:** * *.: * ****::*:. .*:: *:: *:.*.** *. :*.*** :*. : *:**::*.**.*:: ::::: * : :**:**.******::*******:*** *. * .:. : .* . .* :********** ***********:*:**:** ****.*:**:.** ** ::*::*************:** ***: : : : * *: :*** ::** *:: ***.**:** . . * :.**:********* **:**::***** :******** **:********:********** ***.:*:.** *.*** *.:**.*.: ***** *:. : *.:*..**.**:***:.*::* ******:**:**.:***::**** ** *:**** ** .:********:***.:: .::: .**:* . :: * *** ::**.** ****.:************ : ******:*****::*: *:* ** :.::* . : *:**: . . :. . *: . :. .: . .: * *. : : : *:.::* **: * :* : .. : **.::*: .: : .*:::* : * : ::. :. .:: * : :*: :*:: : : . : .* . **.. . * *:. ::**.:: :. : : :: *::* :. **::.:*. .. : *. : * ::.*. : ** . : ** :. . ::.:: ::.*.. . * .: :*. :: . . .**. .::. : * :.: *:*: :: :*:. * : :* ::* . : : : *:** : ::.* *. . :. :. .:* ::*: *: * : *:::** *::.* :** . .: ** ** : * * ::: *.:* * * ::: ::.*:*.::* * ::: **:. .:.: : : ..: . *:.. ::.:::.*: * * .* :* : : *::.. : *.* *: ::*: :* :*::: **. **::::**: *:*:: : * .:. .* :*: .:::.: * : :.:.: *::::*** *:.*: . :: .: . .: : *: . : . . . ::. . : ::: : *: *: .* **::: : :.: :... ::. *.:::*::. : **:. *::.**. * :: :.:*. * . *:*:** : : * .* .::. :: ::: *: .: :: :*** * :* :*. :. .* *** : : : : : *.::* : :. * . : ", "identical_positions": 703, "similar_positions": 710, "identity": "29.74%" }, { "cls_id": "homologset.agr.MGI:1196396", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F7EMK2-1", "uniprot_id": "F7EMK2_RAT", "id": "F7EMK2-1", "name": "UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase", "aln": "------------MWAFPELPLPLPLLVNLIGSLLGFVATVTLIPAFRSHFIAARLCGQDLNKLSRQQIPESQGVISGAVFLIILFCFIPFPFLN--------------CFVEEQ---CKAFPHHEFVALIGALLAICCMIFLGFADDVLNLRWRHKLLLPTAASLPLLMVYFTNFGNTTIVVPKPFR-WILGLHLDLGILYYVYMGLLAVFCTNAINILAGINGLEAGQSLVISASIIVFNLVEL-EGDYR--DDHVFSLYFMMPFFFTTLGLLYHNWYPSQVFVGDTFCYFAGMTFAVVGILGHFSKTMLLFFMPQVFNFLYSLPQLFQIIPCPRHRMPRLNTKTGKLEMSYSKFKTKSLSFLGTFILKVAESLRLVTVHRGESEDGAFTECNNMTLINLLLKVFGPTHERNLTLFLLLLQVLSSAVTFSIRYQLVRLFYDV-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P42867-1", "uniprot_id": "GPT_MOUSE", "id": "P42867-1", "name": "UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase", "aln": "------------MWAFPELPLPLPLLVNLIGSLLGFVATVTLIPAFRSHFIAARLCGQDLNKLSQQQIPESQGVISGAVFLIILFCFIPFPFLN--------------CFVEEQ---CKAFPHHEFVALIGALLAICCMIFLGFADDVLNLRWRHKLLLPTAASLPLLMVYFTNFGNTTIVVPKPFR-WILGLHLDLGILYYVYMGLLAVFCTNAINILAGINGLEAGQSLVISASIIVFNLVEL-EGDYR--DDHIFSLYFMIPFFFTTLGLLYHNWYPSRVFVGDTFCYFAGMTFAVVGILGHFSKTMLLFFMPQVFNFLYSLPQLFHIIPCPRHRMPRLNAKTGKLEMSYSKFKTKNLSFLGTFILKVAENLRLVTVHQGESEDGAFTECNNMTLINLLLKVFGPIHERNLTLLLLLLQVLSSAATFSIRYQLVRLFYDV-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H3H5-1", "uniprot_id": "GPT_HUMAN", "id": "Q9H3H5-1", "name": "UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase", "aln": "------------MWAFSEL--PMPLLINLIVSLLGFVATVTLIPAFRGHFIAARLCGQDLNKTSRQQIPESQGVISGAVFLIILFCFIPFPFLN--------------CFVKEQ---CKAFPHHEFVALIGALLAICCMIFLGFADDVLNLRWRHKLLLPTAASLPLLMVYFTNFGNTTIVVPKPFR-PILGLHLDLGILYYVYMGLLAVFCTNAINILAGINGLEAGQSLVISASIIVFNLVEL-EGDCR--DDHVFSLYFMIPFFFTTLGLLYHNWYPSRVFVGDTFCYFAGMTFAVVGILGHFSKTMLLFFMPQVFNFLYSLPQLLHIIPCPRHRIPRLNIKTGKLEMSYSKFKTKSLSFLGTFILKVAESLQLVTVHQSETEDGEFTECNNMTLINLLLKVLGPIHERNLTLLLLLLQILGSAITFSIRYQLVRLFYDV-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VK30-1", "uniprot_id": "Q9VK30_DROME", "id": "Q9VK30-1", "name": "UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase", "aln": "------------MSG-------VAIAINAAISGAAYCMTVRMIPRFREMFIKANLFGNDLCKKDKPQVPESFGVLIGCVFLVSLFLFIPIPFAFDEAAATD-------AITGGK---PDTFPHDKFVELIAALLSICCMIFLGFADDVLDLRWRHKLLLPTIATLPLLMVYYVNYNSTTVIMPNFAR-NLIGTSLNIGALYYVFMGMLAVFCTNAINILAGINGLEVGQSFIIAGSILVFNAIELLLGHQV--DSHIFSIYFMLPFLATTLALWKFNKYPSQVFVGDTYCYFAGMTFAVVGILGHFSKTLLLFFLPQILNFLYSTPQLFHFVPCPRHRLPKYDSKTDLLHISTTEFRLEDLNAPGRLMVTVLRNLRLISWHT--KADG-VVRTNNFTLINFVLVVFGPVHERVVTQMLMGFQVLCTLIALTIRYPLANYFYAKT------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P07286-1", "uniprot_id": "GPT_YEAST", "id": "P07286-1", "name": "UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase", "aln": "MLRLFSLALITCLIYYSKNQGPSALVAAVGFGIAGYLATDMLIPRVGKSFIKIGLFGKDLSKPGRPVLPETIGAIPAAVYLFVMFIYIPFIFYKYMVITTSGGGHRDVSVVEDNGMNSNIFPHDKLSEYLSAILCLESTVLLGIADDLFDLRWRHKFFLPAIAAIPLLMVYYVDFGVTHVLIPGFMERWLKKTSVDLGLWYYVYMASMAIFCPNSINILAGVNGLEVGQCIVLAILALLNDLLYFSMGPLATRDSHRFSAVLIIPFLGVSLALWKWNRWPATVFVGDTYCYFAGMVFAVVGILGHFSKTMLLLFIPQIVNFIYSCPQLFKLVPCPRHRLPKFNEKDGLMYPSRANLKEEPPKSIFKPILKLLYCLHLIDLEFD--ENNEIISTSNMTLINLTLVWFGPMREDKLCNTILKLQFCIGILALLGRHAIGAIIFGHDNLWTVR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .: . .: * :** . ** * *:** * .: :**: *.: ..*:*. :* :**: * ... : . ***.:: :.*:*.: . ::**:***:::******::**: *::******:.::. * :::* . : :::* ***:*. :*:**.*:******:****.**.:::: :: : : : * *.* ** :::**: .:*.* * :*: ******:******.*************:**:*:**:.**:** ***::::******:*: : * . : * :::: : . ::.: *:*: . :. . .*:****: * :** :* : :: :*. :: *: : :: ", "identical_positions": 137, "similar_positions": 137, "identity": "30.44%" }, { "cls_id": "homologset.agr.MGI:1196398", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K327-1", "uniprot_id": "CHAP1_MOUSE", "id": "Q8K327-1", "name": "Chromosome alignment-maintaining phosphoprotein 1", "aln": "MEVCQELRKPALSLECGHCSFRGTDYENVQLHMGSIHPEFCDDMDAGGLGKLIFYQKSAKLFHCHKCFFTSKLYANVYYHITARHAASDKWSEQPKEQPSKDTESGKSPSPPERQNPAFDPAEARPTPALPMEAQKTSPSLCPESQASGPP-VLEPQGAGPLISPEPQAPCLPAEASKAAPVPCPERVD--PPCELPELE-----KPERGP--SPESVKSALVSSKPPKHSSFADTGAAPSALSPESPVLATSPEPWGPSLSASPESRKPARTASPEPRKPSPAESPELWKPFPAIASEPRRPTPAVSPGSWKPGPPGSPRPWKSSPSATSGPWKSSKPVQPMSPGPWKPIPSVSPGPWKPAPSMSTASWKSS-VSSGSWKTPPTSPESWKSGPPELRKTALPLSPEHWKAVPPVSPELRRPGPPLSPEIRSPAGSPELKKPSSSPDLWKVSPDQRKTSPASLDFPEPQKSSCGSPPDLWKSSFIMESQKPNVFSETRKHTASGSSESPKVASDIWKPVLSIDAEPRKSTLFPEPTKAVLPASPEPRKRALFPESRKHVFLPELPKSAVFSDAQKAPELSEEIQLEAVDNAKCDSLAQEGLLATPKKLLDEALSPSSKKLKKDSQENSDAELSSSEYIRADLDTLDTKGQESSSDQEQVDVESIDFSKENKMEMGSTEQAKNVLQFTEEKEAFISEEEIAKYMKRGKGKYYCKICCCRAMKKGAVLHHLVNKHNVHSPYKCTICGKAFLLESLLKNHVAAHGQSLLKCPRCNFESNFPRGFKKHLTHCQSRHNEEVNKKLMEALESPLEEQQI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96JM3-1", "uniprot_id": "CHAP1_HUMAN", "id": "Q96JM3-1", "name": "Chromosome alignment-maintaining phosphoprotein 1", "aln": "MEAFQELRKPSARLECDHCSFRGTDYENVQIHMGTIHPEFCDEMDAGGLGKMIFYQKSAKLFHCHKCFFTSKMYSNVYYHITSKHASPDKWNDKPKNQLNKETDPVKSPPLPEHQKIPCNSAEPKSIPALSMETQKLGSVLSPESPKPTPLTPLEPQKPGSVVSPELQTPLPSPEPSKPASVSSPEPPKSVPVCESQKLAPVPSPEPQKPAPVSPESVKATLSNPKPQKQSHFPETLGPPSASSPESPVLAASPEPWGPSPAASPESRKSARTTSPEPRKPSPSESPEPWKPFPAVSPEPRRPAPAVSPGSWKPGPPGSPRPWKSNPSASSGPWKPAKPAPSVSPGPWKPIPSVSPGPWKPTPSVSSASWKSSSVSPSSWKSPPASPESWKSGPPELRKTAPTLSPEHWKAVPPVSPELRKPGPPLSPEIRSPAGSPELRKPSGSPDLWKLSPDQRKTSPASLDFPESQKSSRGGSPDLWKSSFFIEPQKP-VFPETRKPGPSGPSESPKAASDIWKPVLSIDTEPRKPALFPEPAKTAPPASPEARKRALFPEPRKHALFPELPKSALFSESQKAVELGDELQIDAIDDQKCDILVQEELLASPKKLLEDTLFPSSKKLKKDNQESSDAELSSSEYIKTDLDAMDIKGQESSSDQEQVDVESIDFSKENKMDMTSPEQSRNVLQFTEEKEAFISEEEIAKYMKRGKGKYYCKICCCRAMKKGAVLHHLVNKHNVHSPYKCTICGKAFLLESLLKNHVAAHGQSLLKCPRCNFESNFPRGFKKHLTHCQSRHNEEANKKLMEALEPPLEEQQI", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**. ******: ***.*************:***:*******:********:********************:*:*******::**:.***.::**:* .*:*:. ***. **:*: . :.**.:. ***.**:** .. *.*** . * **** .*.::*** *:* ..*.**.*.*..** . * ** :* :*:: . ******::* ..** *:* *.:* ..*** ********:******** :*******.***:*********:**** ******::.*****:*********************.***:*****.:**. .:******************:**:*:****** **..***:**:**************** .*****************:******************:***.******:****************.**** *..********::*.*** **.**** .**.*****.************:****.:*****:*:. *****.********.***.::*******:**::*** **.:*:*::*:*: *** *.** ***:*****:::* *********.**.***********::***::* *************************:* *.**::******************************************************************************************************************.*********.*******", "identical_positions": 615, "similar_positions": 139, "identity": "75.65%" }, { "cls_id": "homologset.agr.MGI:1196400", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6ARB3-1", "uniprot_id": "A0A8I6ARB3_RAT", "id": "A0A8I6ARB3-1", "name": "", "aln": "MCATRRGARCSPRRRRGGEFAQGRGSQSERRRAEGGRTPRGGVGTWGPGWAGPAALPVGGSGWRRRPGRGGARCRLRCGGGGNNSADRGARTASRGAGRGTMNEEEQFVNIDLNDDNICSVCKLGTDKDTLSFCHICFELNLEGVPKSNLLHTKSLRGHKDCFEKYHLIANQDCSRSKLSKSTYEGVKTILSKKINWIVQYAQNKNLDLDSECSKTSQHHLFNFRHKPEKKLLPQFDSQVPKYSAKG-LAGSAVGISSYTQRILDHREDTDFGLGILEDADA-------LWTHSHNQAQKTEETSSVPERSVQTQSPRYSREELNSMTLAEVVQLSTKLRQQIQEVFEELTHQVQEKDSLASELHVRHVAIEQLLKNCSKLPCLQVGRTGTRPHLSTNN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D7G4-1", "uniprot_id": "EURL_MOUSE", "id": "Q9D7G4-1", "name": "Protein EURL homolog", "aln": "-----------------------------------------------------------------------------------------------------MNEEEQFVSIDLNDDNICSVCKLGTDKDTLSFCHICFELNLEGVPKSNLLHTKSVRGHKDCFEKYHLIANQDCSRSKLSKSTYEGVKTIVSKKINWIVQYAQNKNLDLESECSKTSQHPLLNFRHKPEKKLLPQFDSQVPKYSAKG-SAGNAGSISSYAQRILEHRENTDFRLGLLEDADA-------LWTHSHSQAQKTEETSSGPEGTIQTQNPHYSREELNSMTLAEVVQLSAKLQQRIQEVFEELTHQVQEKDSLASELHVRHVAIEQLLKNCSKLPCLQVGRTGTRSHLPMNH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NYK6-1", "uniprot_id": "EURL_HUMAN", "id": "Q9NYK6-1", "name": "Protein EURL homolog", "aln": "-----------------------------------------------------------------------------------------------------MNEEEQFVNIDLNDDNICSVCKLGTDKETLSFCHICFELNIEGVPKSDLLHTKSLRGHKDCFEKYHLIANQGCPRSKLSKSTYEEVKTILSKKINWIVQYAQNKDLDSDSECSKNPQHHLFNFRHKPEEKLLPQFDSQVPKYSAKW-IDGSAGGISNCTQRILEQRENTDFGLSMLQDSGATLCRNSVLWPHSHNQAQKKEETISSPEANVQTQHPHYSREELNSMTLGEVEQLNAKLLQQIQEVFEELTHQVQEKDSLASQLHVRHVAIEQLLKNCSKLPCLQVGRTGMKSHLPINN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q503Y8-1", "uniprot_id": "EURL_DANRE", "id": "Q503Y8-1", "name": "Protein EURL homolog", "aln": "-----------------------------------------------------------------------------------------------------MEEEEHFVNIDLNDDNICSICKLETDTGTLSFCHVCFELSIEGISSATLLHSKSLRGHRDCFEKYHLIANQKLSRAKASHSTYEGVKRALSQRINRIIQYAQNRDSVTPENPGRWGAKQILCHTQQAGRKLVPQSDAQVPRYAPRWTEEASMVSESDYGKSMLDCHSAEELGLG--------------LWPGERPQNREQRDSR-------QRRHSGHSREELMRKNVEELRQLNEQLLLQIQNVFEELSVVVQEKDSLSSELHVRHIAIEQLFKNCAKLPWLQIGRAGVKAANNPVE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:***:**.**********:*** **. ******:****.:**:..: ***:**:***:************ .*:* *:**** ** :*::** *:*****:: .: .: : :: . ::. .**:** *:***:*:.: .. . *. : :*: :. :: *. **. .: * :: .:: * : . :***** .: *: **. :* :**:*****: *******:*:*****:*****:***:*** **:**:* :. .", "identical_positions": 132, "similar_positions": 83, "identity": "33.08%" }, { "cls_id": "homologset.agr.MGI:1196403", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P39105-1", "uniprot_id": "PLB1_YEAST", "id": "P39105-1", "name": "Lysophospholipase 1", "aln": "------------MKLQSLLVSAAVLTSLTENVNAWSPN-NSYVPANVTCD-DDINLVREASGLSDNETEWLKKRDAYTKEALHSFLNRATSNFSDTS-LLSTLFGS-NSSNMPKIAVACSGGGYRAMLSGAGMLAAMDNRTDGANEHGLGGLLQGATYLAGLSGGNWLTSTLAWNNWTSVQAIVDNTTESNSIWDISHSILTPDGINIFKTGSRWDDISDDVQDKKDAGFNISLADVWGRALAYNFWPSLHRGGVGYTWSTLREADVFKNGEMPFPITVADGRYPGTTVINLNATLFEFNPFEMGSWDPTLNAFTDVKYLGTNVTNGKPVNKGQCIAGFDNTGFITATSSTLFN--QFLLRLNSTDLPSFIANLATDFL-EDLSDNSDDIAIYAPNPFKEANFLQKNATSSIIESEYLFLVDGGEDNQNIPLVPLLQKERELDVIFALDNSADTDDYWPDGASLVNTYQRQ-------FGSQGLNLSFPYVPDVNTFVNLGLNKKPTFFGCDARN-LTDLEYIPPLIVYIPNSRHSFNGNQSTFKMSYSDSERLGMIKNGFEAATMGNFTDDSDFLGCVGCAIIRRKQQNLNATLPSECSQCFTN----YCWNGTIDSRS---VSG------------------------------VGNDDYSSSASLSASAAAASASAS--------ASASASASASGSSTHKKNAGN-------------ALVNYSNLNTNTFIGVLSVISAVFGLI", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q03674-1", "uniprot_id": "PLB2_YEAST", "id": "Q03674-1", "name": "Lysophospholipase 2", "aln": "------------MQLRNILQASSLISGLSLAADSSSTTGDGYAPSIIPCPSDDTSLVRNASGLSTAETDWLKKRDAYTKEALHSFLSRATSNFSDTS-LLSTLFSS-NSSNVPKIGIACSGGGYRAMLGGAGMIAAMDNRTDGANEHGLGGLLQSSTYLSGLSGGNWLTGTLAWNNWTSVQEIVDHMSESDSIWNITKSIVNPGGSNLTYTIERWESIVQEVQAKSDAGFNISLSDLWARALSYNFFPSLPDAGSALTWSSLRDVDVFKNGEMPLPITVADGRYPGTTVINLNATLFEFTPFEMGSWDPSLNAFTDVKYLGTNVTNGKPVNKDQCVSGYDNAGFVIATSASLFN--EFSLEASTSTYYKMINSFANKYV-NNLSQDDDDIAIYAANPFKDTEFVDRNYTSSIVDADDLFLVDGGEDGQNLPLVPLIKKERDLDVVFALDISDNTDESWPSGVCMTNTYERQ-------YSKQGKGMAFPYVPDVNTFLNLGLTNKPTFFGCDAKN-LTDLEYIPPLVVYIPNTKHSFNGNQSTLKMNYNVTERLGMIRNGFEAATMGNFTDDSNFLGCIGCAIIRRKQESLNATLPPECTKCFAD----YCWNGTLSTSANPELSGNSTYQSGAIASAISEATDGIPITALLGSSTSGNTTSNSTTSTSSNVTSNSNSSSNTTLNSNSSSSSISSSTARSSSSTANKAN-------------AAA-ISYANTNTLMSLLGAITALFGLI", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q08108-1", "uniprot_id": "PLB3_YEAST", "id": "Q08108-1", "name": "Lysophospholipase 3", "aln": "--------MIRPLCSKIIISYIFAISQFLLAANAWSPT-DSYVPGTVSCP-DDINLVREATSISQNESAWLEKRNKVTSVALKDFLTRATANFSDSSEVLSKLFNDGNSENLPKIAVAVSGGGYRSMLTGAGVLAAMDNRTEGAYEHGLGGLLQSTTYLSGASGGNWLVGTLALNNWTSVQDILNNMQNDDSIWDLSDSIVTPGGINIFKTAKRWDHISNAVESKQNADYNTSLADIWGRALAYNFFPSLNRGGIGLTWSSIRDFPVFQNAEMPFPISVADGRYPGTKVINLNATVFEFNPFEMGSWDPSLNSFANVKYLGTNVSNGVPLERGKCTAGFDNAGFIMGTSSTLFN--QFLLRINSTHLPSFITRLARHFL-KDLSQDFNDIAVYSPNPFKDTKFLDSDYTTSIVDSDSLFLVDGGEDDENVPVLPLIQKERDVDIIFAVDNSADMRLAWPDGSSLVHTYERQ-------FVKQGQGMSFPYVPDTNTFVNLGLNKKPTFFGCDANN-LTDLQYIPPLVVYLPNAEYSFNSNQSAFKLSYSESQRRSMIQNGFEIATRNNFTDDPEFMGCVGCAIIRRKQQALNITLPPECETCFKN----YCWNGTLDTTPLPDVEKDVHHSFINVN--------------------SFNSSIGQEESLYAGSSASQSSSS-----SSSSSSSSEIPSATATLEKKAATN-------------SGSHLSGISVKFSAMIMLTLLMFTGAV", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q64GA5-1", "uniprot_id": "PA24C_MOUSE", "id": "Q64GA5-1", "name": "Cytosolic phospholipase A2 gamma", "aln": "--------------------------------------------------MELSSGVCPATRLQEAEKAAVHKRSPKVLEALRKLN--------------------IQADQAPVIAVLGSGGGLRAHIACLGVLSELKEL----------GLLDAVTYLAGVSGSTWALSSLYTK--------------NGNMEGIEEELKHRYEKNEWDFHESLEKAIQASKRE-----NYSLTDFWAYLIVSRQIRELQDS----NLSSLKKQVEEGVLPYPIFAAIDEDLLADWRERKTQNSWFEFTPHHAG--YPALGAYVPITEFGSRFENGKLVKSEPERDLTFLRGLWGSAFADIKEIKNYILNYFRNPFGKLK---FIEG----PVTYSEAPRMNVDAMLLDLVMAYFTDMNDPSIKDKLCALQQALGTETDEFGIEMAEIIQNWNETSAEKKEQFLDHLLDRFKKTQEDTTT--YSLMNWNTGLVWDRCVFVNETRKCVSKWQWGTVYNFLYKHGK-IADETMCSRELLHLVDAGFAIN-TPYPLVLPPVRETHLILSFDFSAGDPLETIRATADYCQRHEIPFPEVSEDQLKEWAKAPASCYVLR----GETGPVVMHFTLFNKDN------------------------------CGDDIETWRKKYGTVKLSDSYTPDLVRDLLRVSKENVKKNKINILSEMRKVAGNPGNIPRVNKEACLGDRVKDPQGSQ-TVEFKKSHNISKD-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1LY61-1", "uniprot_id": "F1LY61_RAT", "id": "F1LY61-1", "name": "", "aln": "-----------------------------------------MSCAESPKSQHKRSGVYFATGLQEEEKGAVHKRSFKVLEGLKKLN--------------------IQADQAPVIAVLGSGGGLRAHIACLGMLSAMKEL----------GLLDAVTYLAGVSGSTWALSSFYTK--------------NGNMQGMEEELKHRYEKNEWHFDESLDKAIQASRRE-----NYSLTDFWAYLVVSRQTRELHDS----NLSGFKKQVEEGVLPYPIFAAIDDDLQDDWREKKVQNSWFEFTPHHAG--YPALRAYVPITEFGSRFENGKLVRPEPERDLTFLRGLWGSALADIKEDKAFIMDYFKDMHEKLKKKYLHRGG-AKTVTYSNAEQMDVDEMFLDLLMAYAIDQDDPSIKDKLCVMQQALGPETGEFGKEMAEIIQNWNEISPEKKEQFLDYLLDYLKKPQEPITYSLRSIGNWIGDLFYDALTFVRKTGMCLWEWQWGTVYNFLYKHGN-IADETMCNREFLHLVDAGLAIN-TPYPLILTPVREAHLILSFDFSAGDPFETIRVTADYCHQHKIPFPEVSEDQLKELAKSPKSCYILR----GETGPVVMHFPLFNKDN------------------------------CGDDIETWRKKYKTMKLSDSYTPSMVTDLLRVSKENVQKNKEKIVNEMREVTG------------------HYLQRTT-PCALSKIHH-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UP65-1", "uniprot_id": "PA24C_HUMAN", "id": "Q9UP65-1", "name": "Cytosolic phospholipase A2 gamma", "aln": "---------------------------------------------------MGSSEVSIIPGLQKEEKAAVERRRLHVLKALKKLR--------------------IEADEAPVVAVLGSGGGLRAHIACLGVLSEMKEQ----------GLLDAVTYLAGVSGSTWAISSLYTN--------------DGDMEALEADLKHRFTRQEWDLAKSLQKTIQAARSE-----NYSLTDFWAYMVISKQTRELPES----HLSNMKKPVEEGTLPYPIFAAIDNDLQPSWQEARAPETWFEFTPHHAG--FSALGAFVSITHFGSKFKKGRLVRTHPERDLTFLRGLWGSALGNTEVIREYIFDQLRNLTLKG----LWRR------AVANAKSIG------HLIFARLLRLQESSQGEHPPPEDEGGEPE----HTWLTEMLENWTRTSLEKQE-----------QPHEDPER---------KGSLSNLMDFVKKTGICASKWEWGTTHNFLYKHGG-IRDKIMSSRKHLHLVDAGLAIN-TPFPLVLPPTREVHLILSFDFSAGDPFETIRATTDYCRRHKIPFPQVEEAELDLWSKAPASCYILK----GETGPVVMHFPLFNIDA------------------------------CGGDIEAWSDTYDTFKLADTYTLDVVVLLLALAKKNVRENKKKILRELMNVAG-----------------LYYPKDSARSCCLA---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P53541-1", "uniprot_id": "SPO1_YEAST", "id": "P53541-1", "name": "Putative meiotic phospholipase SPO1", "aln": "------------------------MQKLLFVFSVLLTVVLATAPFQVQCP-SSPLIREAKHELCPEETLYLKKKKIKTKNKLIQFLKSLTEAKFSSK------FYKRVLKDPPKIGIAISGGGYRSMLVGTGFISQMNDY----------GLFEYSDYIAGLSGGSWILMDLVVQNFEVKSLLQEWDLEEDLLLGIPEFDISEEEIVTNAKKEYNDNDLKMKKRQ---GGSLITSSSNFYEQIEEIMNSIEEIPEDYMITKRNLNPLARLKKIFFPNNTFTGTDAKIETFKKVLDFYKSLHLKIKPKKMEGFQISFTDYWGKAIVQRLKKNFDDDPNHSFSFSKLVNSSKKFKECSVPIPIFVANCKNGLLSNVIFEFTPFEFGSWENILRLFVKLPYLGSKIVSGKAEKCINNFDDLGFITATSSSIFNNVLIFIWNLASQSSREAMKALNMVMGIFGLGKEEIFSISKD-----SSRLETDYAVYQPNPFYLYPEKDNVLTNKNHLYLVDGGE-DGENIPLRTLVIPERELDVIFVLDSSSDIDNYPNGSKLKRIFEKLDEENVHYQFPNNVKTFTHPIVIGCNATKRTGHDSFLPIIIYHAN----ANHGNASNTSTFKITYN--------------------------------QSEVSSMLPTGRGVFSN-------------DYDLYYKNCLGCILTKRTMDR------------------LPRKKKFSPFCLQCFKDYCYS-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "A0AC58JND6-1", "uniprot_id": "A0AC58JND6_DANRE", "id": "A0AC58JND6-1", "name": "", "aln": "MKLFSSVADSSKTLLPVQNKQTRNHLGFVAYSCCTETVSNCDPKTKMSASNVQESEVRIAHSLNMKEAACVKKRRSEIWSSLKTLG------------------INCSQDKVPNIALLGSGGGQRAMVGLLGSLDQLDKT----------GLLSCLLYLSGVSGSTWCMASLYQEP-----------DWSTKLQAVKEKIVRRISGPPVSWSDAYAKLKKYYREKE----YFSLTDVWATMVVTTYVKEIDER----TFTDWLGQSKNN--PFPIYTLIDKECKQSGD----GDPWFEISPCEAG--YSLTGAFVKTPSFGSQFVNGRKTTSQPEMDMLLLQALCGSALADGEENKKFLWSKIKGLFRHASDQMIEQME---------------QDPILQQVDTCSDVLEELAAINICLLDGEDPTTLDHSIRKSLKDLAGHDPQLISPDKSSEDEYTLEVCGLLEELQVK--------LNISWPVDLKMWIRIFVCMAKWTWGRNYDFLYNMRDPAVPAALLKSKTRDYEDAGLLLN-SPYFSVLRTERKIDIIISLDFSEGDPFQTVKEAAEACRKLKIPFPPIN--LLAEDIKNPKDFYVFKNTSTDKKAPTVIHIPLFNVIN------------------------------CGDKLGQYRKNYTT--FQGAYSAEKIIDLMNVAGKNISNNKQELINVINEVIR---------------------KK-----------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * :.:: * : .. * :.: **** *: : * : :.. **:. *::* **..* : : . : : . . . : :. .: : : :: . *. . : . : : : . : . : : : : . . . ", "identical_positions": 17, "similar_positions": 58, "identity": "2.27%" }, { "cls_id": "homologset.agr.MGI:1196405", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XIK8-1", "uniprot_id": "CTSL2_RAT", "id": "Q5XIK8-1", "name": "CTD small phosphatase-like protein 2", "aln": "MKLRTRKASQQSSPIQTQRTARAKRKYSEVDDSLPSGGEKPSKNETGLLSSIKKFIKGSTPKEERENPSKRSRIERDIDNNLITSTP-RTGEKPDKQLSRVRRKSPVNGEAGSYEMTNQHIKQNGKLEDNPCS-GSPPRTTLLGTIFSPVFNFFSPANKNGTSGSDSPGQAVEAEEIVKQLDMEQVDEITTS-TTSAN----GAAYSNQAVQVR--PSLNNGLEEAEETVTRDIPPLTAPVAPES-GYS----SAHAEATYEEDWEVFDPYYFIKHVPPLTEEQLNRKPALPLKTRSTPEFSLVLDLDETLVHCSLNELEDAALTFPVLFQDVIYQVYVRLRPFFREFLERMSQMYEIILFTASKKVYADKLLNILDPKKQLVRHRLFREHCVCVQGNYIKDLNILGRDLSKTIIIDNSPQAFAYQLSNGIPIESWFMDKNDNELLKLIPFLEKLVELNEDVRPHIRDRFRLHDLLPPD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BG15-1", "uniprot_id": "CTSL2_MOUSE", "id": "Q8BG15-1", "name": "CTD small phosphatase-like protein 2", "aln": "MKLRTRKASQQSSPIQTQRTARAKRKYSEVDDSLPSGGEKPSKNETGLLSSIKKFIKGSTPKEERENPSKRSRIERDIDNNLITSTP-RTGEKPDKQLSRVRRKSPVNGEAGSYEMTNQHIKQNGKLEDNPCS-GSPPRTTLLGTIFSPVFNFFSPANKNGTSGSDSPGQAVEAEEIVKQLDMEQVDEITTS-TTSAN----GAAYSNQAVQVR--PSLNNGLEEAEETVTRDIPPLTAPVTPES-GYS----SAHAEATYEEDWEVFDPYYFIKHVPPLTEEQLNRKPALPLKTRSTPEFSLVLDLDETLVHCSLNELEDAALTFPVLFQDVIYQVYVRLRPFFREFLERMSQMYEIILFTASKKVYADKLLNILDPKKQLVRHRLFREHCVCVQGNYIKDLNILGRDLSKTIIIDNSPQAFAYQLSNGIPIESWFMDKNDNELLKLIPFLEKLVELNEDVRPHIRDRFRLHDLLPPD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q05D32-1", "uniprot_id": "CTSL2_HUMAN", "id": "Q05D32-1", "name": "CTD small phosphatase-like protein 2", "aln": "MRLRTRKASQQSNQIQTQRTARAKRKYSEVDDSLPSGGEKPSKNETGLLSSIKKFIKGSTPKEERENPSKRSRIERDIDNNLITSTP-RAGEKPNKQISRVRRKSQVNGEAGSYEMTNQHVKQNGKLEDNPSS-GSPPRTTLLGTIFSPVFNFFSPANKNGTSGSDSPGQAVEAEEIVKQLDMEQVDEITTSTTTSTN----GAAYSNQAVQVR--PSLNNGLEEAEETVNRDIPPLTAPVTPDS-GYS----SAHAEATYEEDWEVFDPYYFIKHVPPLTEEQLNRKPALPLKTRSTPEFSLVLDLDETLVHCSLNELEDAALTFPVLFQDVIYQVYVRLRPFFREFLERMSQMYEIILFTASKKVYADKLLNILDPKKQLVRHRLFREHCVCVQGNYIKDLNILGRDLSKTIIIDNSPQAFAYQLSNGIPIESWFMDKNDNELLKLIPFLEKLVELNEDVRPHIRDRFRLHDLLPPD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q08BB5-1", "uniprot_id": "CTL2A_DANRE", "id": "Q08BB5-1", "name": "CTD small phosphatase-like protein 2-A", "aln": "MRLRVRKASQQRSATPSARTVKTKRKHSEVEHSLSTEDAKMQKRDTGIFSTIKRFIRGNAVKVEQCTPAKRSRVDCDSDSNLITSTP-TGGNLPSRANPKTRRKGPVNGDT--MTGQNKPVKPNGKLEVQAETPSSPPRTTLLGTIFSPVFSFFSPANKNATAGSDSPGQAVEAEEIVKQLDMEQLEETPTSTTTDGR----DLTFD-PALNPRPLPHIDTTVEEGEIVTEADMPPLTA-VGSNS-NYPDVPPSPPAEGTYEEDWEVFDPYFFIKHVPPLTEEQLTRKPALPLKTRSTPEFSLVLDLDETLVHCSLNELEDAALTFPVLFQDVIYQVYVRLRPFFREFLERMSQIYEIILFTASKKVYADKLLNILDPKKQLVRHRLFREHCVCVQGNYIKDLNILGRDLSKTVIIDNSPQAFAYQLSNGIPIESWFVDKNDNELLKLVPFLEKLVELNEDVRPYIRERFRLHDLLPPD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A4QNX6-1", "uniprot_id": "CTL2B_DANRE", "id": "A4QNX6-1", "name": "CTD small phosphatase-like protein 2-B", "aln": "MRLRMRKDSQQPTLARRACPARTKRKSSEVEECTG--------ESKALLSSIKKFIHGSSIKVEQDNPAKTSHLSCE----LITSTPQRKNDLQRKSIYRARRRTSINGETTNHDTN----KPNGKLEVTEEVVSSPPRTTLLGTIFSPVFNFFSPANKN---ASNSPDQVVEAEEIVKQLEMEQVEEMPTCTATSREPLSVPLYTSAMTSAFRPPPTAHTPEQESENTPHPDLPPLTAPGSPATGGYVDASITVPAEGSYEEEWEVFDPYFFIKHVPPLTEEQLTRKPALPLKTRSTPEFSLVLDLDETLVHCSLNELDDAALTFPVLFQDVIYQVYVRLRPFFREFLERMSQIYEIILFTASKKVYADKLLNILDPRKQLVRHRLFREHCVCVQGNYIKDLNILGRDLSKTIIIDNSPQAFAYQLSNGIPIESWFMDRNDSELLKLVPFLEKLVELNEDVRPHVRERFRLHDLLPPD", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:** ** *** . ..::*** ***:.. ....::*:**:**:*.: * *: .*:* *::. : ****** .: : :.**: :**:: * ***** .****************.******** .*:**.*.**********:***::* .*. :*. . . : * * .. :*.* . *:***** . : .* : **.:***:*******:*************.*********************************:**********************************:***********************:**********************************:***********************:*:**.*****:***************::*:***********", "identical_positions": 303, "similar_positions": 78, "identity": "63.26%" }, { "cls_id": "homologset.agr.MGI:1196412", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4AAM0-1", "uniprot_id": "D4AAM0_RAT", "id": "D4AAM0-1", "name": "Transportin-3", "aln": "MEGAKPTLQLVYQAVQALYHDPDPSGKERASFWLGELQRSVHAWEISDQLLQIRQD----VESCYFAAQTMKMKIQTSFYELPTDSHASLRDSLLTHIQNLKDLSP-VIVTQLALAIADLALQMPSWKGCVQTLVEKYSNDVTSLPFLLEILTVLPEEVHSRSLRIGANRRTEIIEDLAFYSSTVVSLLMTCVEKAGTD------EKMLMKVFRCLGSWFNLGVLDSNFMANNKLLALLFEVLQQDKTSSNLHEAASDCVCSALYAIEN-----VETNLPLAMQLFQGVLTLETAYHMAVAREDLDKVLN-YCRIFTELCETFLEKIVCTPGQGLGDLRTLELLLICAGHPQYEVVEISFNFWYRLGEHLYKTNDEVIHSIFKAYIQRLLHALARHCQLEPDHEGVPEETDDFGEFRMRVSDLVKDLIFLIGSMECFAQLYSTLK---EGNPPWEVTEAVLFIMAAIAKSVDPENNPTLVEVLEGVVHLPETVHTAVRYTSIELVGEMSEVVDRNPQFLDPVLGYLMKGLCEKP-------LASAAAKAIHNICSVCRDHMAQHFNGLLEIAHSLDSFMLSPEAAVGLLKGTALVLARLPLDKITECLSELCSVQVMALKKLLSQE---PSNGISSDPTVFLDRLAVIFRHTNP--IVENGQTHPCQKVIQEIWPVLSETLNKH--RADNRIVERCCRCLRFAVRCVGKGSAALLQPLVTQMVNVYHVHQHSCFLYLGSILVDEYGMEE--GCRQGLLDMLQALCIPTFQLLEQ------QNGLQNHPDTVDDLFRLATRFIQRSPVTLLRS-QVVIPILQWAIAST-TLDHRDANSSVMRFLRDLIHTGVAND-------HEEDFEVRKELIGQVMDQLGQQLVSQLLHTCCFCLPPYTLPDVAEVLWEIMQVDR-PTFCRWLENSLKGLPKETTVGAVTVTHK-QLTDFHKQVTSAEECKQVCWALRDFTRLFR---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6P2B1-1", "uniprot_id": "TNPO3_MOUSE", "id": "Q6P2B1-1", "name": "Transportin-3", "aln": "MEGAKPTLQLVYQAVQALYHDPDPSGKERASFWLGELQRSVHAWEISDQLLQIRQD----VESCYFAAQTMKMKIQTSFYELPTDSHASLRDSLLTHIQNLKDLSP-VIVTQLALAIADLALQMPSWKGCVQTLVEKYSNDVTSLPFLLEILTVLPEEVHSRSLRIGANRRTEIIEDLAFYSSTVVSLLMTCVEKAGTD------EKMLMKVFRCLGSWFNLGVLDSNFMANNKLLALLFEVLQQDKTSSNLHEAASDCVCSALYAIEN-----VETNLPLAMQLFQGVLTLETAYHMAVAREDLDKVLN-YCRIFTELCETFLEKIVCTPGQGLGDLRTLELLLICAGHPQYEVVEISFNFWYRLGEHLYKTNDEVIHSIFKAYIQRLLHALARHCQLEPDHEGVPEETDDFGEFRMRVSDLVKDLIFLIGSMECFAQLYSTLK---EGNPPWEVTEAVLFIMAAIAKSVDPENNPTLVEVLEGVVHLPETVHTAVRYTSIELVGEMSEVVDRNPQFLDPVLGYLMKGLCEKP-------LASAAAKAIHNICSVCRDHMAQHFNGLLEIAHSLDSFMLSPEAAVGLLKGTALVLARLPLDKITECLSELCSVQVMALKKLLSQE---PSNGISSDPTVFLDRLAVIFRHTNP--IVENGQTHPCQKVIQEIWPVLSETLNKH--RADNRIVERCCRCLRFAVRCVGKGSAALLQPLVTQMVNVYHVHQHSCFLYLGSILVDEYGMEE--GCRQGLLDMLQALCIPTFQLLEQ------QNGLQNHPDTVDDLFRLATRFIQRSPVTLLRS-QVVIPILQWAIAST-TLDHRDANSSVMRFLRDLIHTGVAND-------HEEDFELRKELIGQVMSQLGQQLVSQLLHTCCFCLPPYTLPDVAEVLWEIMQVDR-PTFCRWLENSLKGLPKETTVGAVTVTHK-QLTDFHKQVTSAEECKQVCWALRDFTRLFR---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y5L0-2", "uniprot_id": "TNPO3_HUMAN", "id": "Q9Y5L0-2", "name": "Transportin-3", "aln": "MEGAKPTLQLVYQAVQALYHDPDPSGKERASFWLGELQRSVHAWEISDQLLQIRQD----VESCYFAAQTMKMKIQTSFYELPTDSHASLRDSLLTHIQNLKDLSP-VIVTQLALAIADLALQMPSWKGCVQTLVEKYSNDVTSLPFLLEILTVLPEEVHSRSLRIGANRRTEIIEDLAFYSSTVVSLLMTCVEKAGTD------EKMLMKVFRCLGSWFNLGVLDSNFMANNKLLALLFEVLQQDKTSSNLHEAASDCVCSALYAIEN-----VETNLPLAMQLFQGVLTLETAYHMAVAREDLDKVLN-YCRIFTELCETFLEKIVCTPGQGLGDLRTLELLLICAGHPQYEVVEISFNFWYRLGEHLYKTNDEVIHGIFKAYIQRLLHALARHCQLEPDHEGVPEETDDFGEFRMRVSDLVKDLIFLIGSMECFAQLYSTLK---EGNPPWEVTEAVLFIMAAIAKSVDPENNPTLVEVLEGVVRLPETVHTAVRYTSIELVGEMSEVVDRNPQFLDPVLGYLMKGLCEKP-------LASAAAKAIHNICSVCRDHMAQHFNGLLEIARSLDSFLLSPEAAVGLLKGTALVLARLPLDKITECLSELCSVQVMALKKLLSQE---PSNGISSDPTVFLDRLAVIFRHTNP--IVENGQTHPCQKVIQEIWPVLSETLNKH--RADNRIVERCCRCLRFAVRCVGKGSAALLQPLVTQMVNVYHVHQHSCFLYLGSILVDEYGMEE--GCRQGLLDMLQALCIPTFQLLEQ------QNGLQNHPDTVDDLFRLATRFIQRSPVTLLRS-QVVIPILQWAIAST-TLDHRDANCSVMRFLRDLIHTGVAND-------HEEDFELRKELIGQVMNQLGQQLVSQLLHTCCFCLPPYTLPDVAEVLWEIMQVDR-PTFCRWLENSLKGLPKETTVGAVTVTHK-QLTDFHKQVTSAEECKQVCWALRDFTRLFR---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VQG0-1", "uniprot_id": "Q9VQG0_DROME", "id": "Q9VQG0-1", "name": "Transportin-3", "aln": "MD--TYSVDVVYQAISALFQGNNPKEQEKANKWLQDFQKSIYSWTIADELLHQKRD----LHANYFAAQTMRNKIQNSFSELPPHTHESLRDSLITHIGQIDEQTDNVIVTQLSLAVADLALLMASWREPINDLLVTLAPHQCAIWPLLEVLKVLPEEIDSRYLRLGANRREEVHKQLDASAECVLKFLCMCLQREDLDQ-----QRVWNAALRTYSAWLVIHAFPVSHVYNNALTQLAFRLLSLPETSGKLHDNATECVCALLSCINTRQDGASDPESSFEAQLFGAVCMLETPYHLSVAHEDTDKTIN-YCRIFTSLCDAFFYDLLADAQKPHYSLKGLDLVLLCVGHFDYEVAEITFHLWYKLSEDLFQRNEDKLTVLFRPHIERLISALFRHSQMESDHDGLIEENNNFFDFRRKVSDLIKDVAFIVGSGACFKQMFHILQ---APETTWESTEAALFIMQNVAKNILPDENEVIPKVVEAILNMSEQTHIAVRYTAILLIGELCDWIENHPESLEAVLNFLLYALQQKNG------LAPAAAIALTSICSACRQKMVCHISGLVEIARSLDSFQINNDVAIGLLKGISLILTRLPREQLQPALREIVGFQLQPLAQLVDSTGSTPQKGERTDPVYWIDRACAIIRHTNP--DVPDNVEHPTVAILNDAWQLISRVMDKY--QSDLRIMERTCRLIRYGIRMVRKQAMMLVEPLIKQMVVLYSVQHHSCFLYVGSILVDEFAKSS--ECIGGLLEMLQAFIEPTFGLLQM------ENGLKNNPDTVDDFFRLASRYLDCCPHQLLQS-SLITPIFQCALIAC-SLDHREANSSVMKFFINLLVWGRSNN-------HSRNTECR-PLVVELASQHGGALVMNLIQASVFQLHSYMLVDVAEVLHELKQVVGNERMQPFLAQALEALPKKNSGGYVTATQQ-QLDEFSSTVLRADTTKAISQALKTFTRLFR---------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q99189-1", "uniprot_id": "MTR10_YEAST", "id": "Q99189-1", "name": "mRNA transport regulator MTR10", "aln": "--MDNLQVSDIETALQCISSTASQDDKNKALQFLEQFQRSTVAWSICNEILSKEDPTNALLELNIFAAQTLRNKVTYDLSQLENN-LPQFKDSLLTLLLSHN---QKLIITQLNVALARLAIQFLEWQNPIFEIISLLNSSPSILLNFLRILPEETLDIASTSLTEVEFN-SRIHELIDPIAEDVLKFLVSCIDLLQNTDGNSSSSISLEQILRCLNSWSYEFPVEQLLTVQPLINLVFETISNGNESDMEAFDSAIDCLCVILRESRDTTNEQLISALFHQLMLLQEKLLPTLFTDHPLNDEYDDDLLEGMTRLFVEAGEAWSVVISKNPD--FFKPMVLVLLMLTCKNEDLDVVSYTFPFWFNFKQSLVLPRYQESRKAYSDIFVKLINGIITHLQYPSGQFSSKEEEDKFKDFRYHMGDVLKDCTAVVGTSEALSQPLIRIKSAIENNNSWQIMEAPLFSLRTMAKEISLTENTILPEIIKIICNLPEQAK--IRYASTLVLGRYTEWTAKHPELLEVQLQYIFNGFQLHEGSSDMQSIITASSHALMFFCSDCSKLLVGYIDQLINFFLNVQS-SIDIESQFELCQGLSAVINNQPEAKVSVIFQKLVDDNLRQIEALIPQWK-ANPTLLAPQIADKIDLLYALFEELKPRYNYPQQGSEPLLPRIEFIWKALRTLLVDAGAMTDSIIVERVAKLLRRIFERFHVFCEPILPSVAEFLIQGYLTTGFGSYLWCSGSLIVIFGDDESFPISPSLKDAVWKFALSQCETFILNFNKFDKLQLNDYHEAIIDFFSLISDLIMFYPGAFLNSTELLGPVLNVALECVNKLDNYDAYICILRCLDDIISWGFKTPPISTVSIEIVPDEWRKQVINEVVIAHGNQLILVLFIGLVTTFENTAHSDAISCIVKCLRILTEANNNDATICIDWIYKVVEQLGQVTLNERDNLAKAVVEGLNSKDYRKVREGIRAFVGWYSRKNINSRFE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :. : *:..: . . :::* :* ::*:* :* *.:::* . :. *****:: *: .: :* . .::***:* : . . :*:*** :*:* **: : .*: : :: : :*.:* . :: * * . .: : : :. *:.:* *:: . :* .:* . : : : : . ::. : .: * :*:* * . . *: . .: * *. :: *:*.. ::: : . . * *::: : : :*.. :* :*:.: : * . : : : :*: .: * * ..: . ** :.* :** ::.*::** ::*: .: * :: : .*: ** ** : :**.: :* : :::: : .:.* .: :**:: ::*. : .:*: *: * ::: .: : : .*:: *: :** * . :. ::. *::: .::* :. : . * :* : :: . * :: : :: . :: : *: . . .: . :* .::.. :* : .* :: * : : . :* *:** .: :* .. . . :: .: :: * . ...:*: .. *: :. .. .* : : : . : : *:: ::: *:* * : : * :*.* .:: *::: *: . .**: :* .::: : ::: * . . * * :: :: * *: *: : *. . : : :: * ** ..: :* . :. : : .:: *. : ", "identical_positions": 128, "similar_positions": 331, "identity": "12.99%" }, { "cls_id": "homologset.agr.MGI:1196415", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5BJQ7-1", "uniprot_id": "TADA1_RAT", "id": "Q5BJQ7-1", "name": "Transcriptional adapter 1", "aln": "-------------------------------------------------------MATFVSELEAAKKNLSEALG-DNVKQYWANLKLWFKQKISKEEFDLEAHRLLTQDN--------------VHSHNDFLLAILTRCQILVSTPEGAGSLPWTGGSA-AKPGKP-KGKKKLSS---------VRQKFDHRFQPQNPLSGAQ-------------------QFVAKDPQDDDDLK---------------------LCSHTMMLPTRGQLEGRMIVTAYEHGLD-NVTEEAVSAVVYAVENHLKDILTSVVS----RRKAYRVR-DGHFKYAFGSNVTPQPYLKNSVVAYNNLVEGPPAFPAPCASQNPASHPHTDDAEQQAAFLLACSGDTLPASLPP-----VNMYDLFEALQVHREVIP-THTVYALN------------IERIIMKLWHPNHEELQQDKVHRQRLAAKEGLLLC--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99LM9-1", "uniprot_id": "TADA1_MOUSE", "id": "Q99LM9-1", "name": "Transcriptional adapter 1", "aln": "-------------------------------------------------------MATFVSELEAAKKNLSEALG-DNVKQYWANLKLWFKQKISKEEFDLEAHRLLTQDN--------------VHSHNDFLLAILTRCQILVSTPEGAGSLPWTGGSA-AKPGKP-KGKKKLSS---------VRQKFDHRFQPQNPLSGAQ-------------------QFVAKEPQGDDDLK---------------------LCSHTMMLPTRGQLEGRMIVTAYEHGLD-NVTEEAVSAVVYAVENHLKDILTSVVS----RRKAYRVR-DGHFKYAFGSNVTPQPYLKNSVVAYNNLVEGPPAFSAPCANQSPASQPHPDDAEQQAAFLLACSGDTLPASLPP-----VNMYDLFEALQVHREVIP-THTVYALN------------IERIIMKLWHPNHEELQQDKVHRQRLAAKEGLLLC--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96BN2-1", "uniprot_id": "TADA1_HUMAN", "id": "Q96BN2-1", "name": "Transcriptional adapter 1", "aln": "-------------------------------------------------------MATFVSELEAAKKNLSEALG-DNVKQYWANLKLWFKQKISKEEFDLEAHRLLTQDN--------------VHSHNDFLLAILTRCQILVSTPDGAGSLPWPGGSA-AKPGKP-KGKKKLSS---------VRQKFDHRFQPQNPLSGAQ-------------------QFVAKDPQDDDDLK---------------------LCSHTMMLPTRGQLEGRMIVTAYEHGLD-NVTEEAVSAVVYAVENHLKDILTSVVS----RRKAYRLR-DGHFKYAFGSNVTPQPYLKNSVVAYNNLIESPPAFTAPCAGQNPASHPPPDDAEQQAALLLACSGDTLPASLPP-----VNMYDLFEALQVHREVIP-THTVYALN------------IERIITKLWHPNHEELQQDKVHRQRLAAKEGLLLC--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NWA8-1", "uniprot_id": "TADA1_DANRE", "id": "Q6NWA8-1", "name": "Transcriptional adapter 1", "aln": "-------------------------------------------------------MAAHASELEIAKKNLTDAIG-ENVKHYWANLKLWFKQKISKEEFDLEARRLLAQDN--------------VHVHNDFLLAILTRCQIIVSTSEGPGSLQWSGGSA-SKPGKPSRGKKKFPS---------VRQKFDHRFQPQNPLAGVP-------------------VFSPREAE-EEELK---------------------LSAQTLLLPSRGQLEARMMVSAFESDLD-SVAEDAVSCMLCALQVHLKDILTALVS----RRKAYRLR-DGHFLYAFGSDVTPRPYLKNSLPAYHSATECPPASASLPAAAP--ARVCPDEAEQNAALLLACSADTAAPPLQP-----VSVYDLLEALQVQRRVMP-SHSMYALN------------MERILARLWHPSHEELEQDHIHRQHLALRDGLVT---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IP99-1", "uniprot_id": "TAD11_DROME", "id": "Q8IP99-1", "name": "Transcriptional adapter 1-1", "aln": "---------------------------------------------------------MLTDRVLATKEALVVALG-DNWERYRANMKNWFRSRWTKEEFDAESRKILTPDK--------------LHLHNQFLLALLNKIDAFAP-LENPPAVQTSSSSG-NRSKRRKRSCRTFAERLNFELSDVLDFVAEDNMQIIRPPTTIG-------------------IPSDQQQQQLQSQR---------------------YCAQELFLPDAGFIMGRFLIGAWEIGLV-SVDDNVAEYVAMAVQVLLKDLLSAIIK----KRKHYKTSGEGNFYYDVGAPLR-DPSLRN-TVTRQKVDDTPLELDKELNTANFMRRQNDD------VTFLSACEEVQPTERTV-----ITLKDCQLALR-DRNLIG-SHAVYSIN------------MERLNMMMH----------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8IPA1-1", "uniprot_id": "TAD12_DROME", "id": "Q8IPA1-1", "name": "Transcriptional adapter 1-2", "aln": "---------------------------------------------------------MLTDRVLATKEALVVALG-DNWERYRANMKNWFRSRWTKEEFDAESRKILTPDK--------------LHLHNQFLLALLNKIDAFAP-LENPPAVQTSSSSG-NRSKRRKRSSRTFAERLNFELSDVLDFVAEDNMQIIRPPTTIG-------------------IPSDQQQQQLQSQR---------------------YCAQELFLPDAGFIMGRFLIGAWEIGLV-SVDDNVAEYVAMAVQVLLKDLLSAIIK----KRKHYKTSGEGNFYYDVGAPLR-DPSLRN-TVTRQKVDDTPLELDKELNTANFMRRQNDD------VTFLSACEEVQPTERTV-----ITLKDCQLALR-DRNLIG-SHAVYSIN------------MERLNMMMH----------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12060-1", "uniprot_id": "HFI1_YEAST", "id": "Q12060-1", "name": "SAGA complex subunit HFI1", "aln": "MSAIQSPAPKPLQPTYPAASPASTNAYMKPGLIGSPAVSNHTEPNNGNNETAEPQGPNQRIDLGAMIEELTSLLGKESWTKYAQIISLFILGKLSRKELSNELELVFSPSAASLEKSNTNHHHSLVRLHNQLLLGIFANSLRENPLGRNGNESSWGFGNGSNNPNNKLKRINKHNSQIEVYKKIVMSLPLNDRNRLKMITKEAGKRGFIFCSVFQARLNNIPKIPIVTNPESLKRVKSNNLKTPLEWSQDIMNGFNVPLASESHSLPDTDSFYLRMVGIAREHGLVGTVDARCVELISLALDQYLKNIIEFTIDTVRYRRKKYSDYYDLNESGLYKSVSEMAADKRDAKIKQLDDDKNEDECADEAKSINNGNNSSKDDIGDISMSSITKAGEAVNEELHENRTISLTNEDIYDSLSIFPNLVEPSGSYYALTNLGLVNDDELVDMKSNIDDLPDFLNEKPTFTPLDERNVGTRHELNWLIKGILTED", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : * :* :. :* :. :: : :::*:. * . ::: . :: **::**.:: . . . ... .. . : .. . : :.. : : : . : .:. ** . : *:: * * .* .* .. : *:: **::: :. :** * : : : . :: . . . * :: . :. :. * :* .:: : : *::. :: : ", "identical_positions": 26, "similar_positions": 98, "identity": "5.33%" }, { "cls_id": "homologset.agr.MGI:1196419", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZKK0-1", "uniprot_id": "A0A8I5ZKK0_RAT", "id": "A0A8I5ZKK0-1", "name": "", "aln": "MSENSSDSDSSCGWTVINHEGSDIEIVNSATASDNGEPTPEYSSPDQEELQVLPEGHGGGESSANITSSVGETMLSLVRETKSATEVEETTSPEDNVYFGTTSDDSDIVTLEPPKLEEMGIQEVAIIK-----DDLNLGSSSSSQYTFCQPEPEKWWEKLWKIPECIRGWDDQLRLRVPSQLALQVFSSQH----SDEESSS---DDTSHEPSPAPRRRRNRKKTVSISESE-----EPLLPEPEDEPSKETSKRHF---SGGLNKCIILALVIAISMGFGHFYGKNEGNKGKGTIQIQKRQQLGRKVHEDELNSVKDYLFQCQQEQECALDFKTQSSKENLERCWTTTESEKVTFETQNNNLAAENKYLRLSLEKEEKTLSSLQEELRQLKEQIRLLEDKGTSTQLVR-ENQVLKRYLEVEKQKTNSFLNERVTLLEEARVLKRDLERERLTAMALRAELEQLAPRQAQGHADSPSVQRGEKEIVLLQQRLAELEQKLSFEQQRSDLWERLYVEAKDQHGKQEADGRKRGSKGSHRVKSKSKETFLGTVKETFDAMKNSTKEFVRHHKEKIKQAKEAVKENLKKFSDSVKSTFRHFKDTTKNIFDEKGSKRFRASKEEATEKPRTAYSYSSYSEREAPDQNQNCRGPSAQRDRGREKPSHSEEIRQTTNSYTYKAKFDCR---GTHSTRKVCSGMFECAGQESISPVNQAG-PVRMNDFKQLIHWYLLNELDTFHHWKELDQFISPFFLNGVFRHDQKPFADFVDDVKGYLKSIKEYQVE-DDNLEKLDGCIYRH-FGHVFALPFGPSRPDK---KQRMVNIENSRHRKQEQKHLHPQPCKREGKWYKYGRANGRHTANLEIELGQLPFDPKY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q640L3-1", "uniprot_id": "CCPG1_MOUSE", "id": "Q640L3-1", "name": "Cell cycle progression protein 1", "aln": "MSESSSDSDSSCGWTVINHEGSDIEIVNSATASDNCGLTLECSLVEQEELPVLYVGHGGEESSANNTSSVGETMLSSMRETKSAAEVEEAPSPEDNVYFGTTSDDSDIVTLEPPKLEEMGNQEVTIQEAP-SSDDLNMGSSSSSQYAFCQPEP--------------------------------VFSSQP----SDEESSS---DDTSHEPSPAPRRRRNRKKTVSISESE-----EPPLAEPEDEPSKEPSKRHF---SRGLNKCVILALVIAVSMGFGHFYG---------TIQIQK--QLVRKTHEDELDGVKGYLSQRKQEQESFLDFKS--LKENLERCWTVTESEKITFETQKKNLAAENQYLRISLEKEEQALSSLQEELRQLREQIRLLEDKGTSTQLVR-ENQVLKQYLEVEKQKTDSFLREREMLLEEARMLKRDLEREQLTAMALRAELEQFIPGQAQSRAESPSVQTEEKEVGLLQQRLAELEQKLIFEQQRSDLWERLYVEAKDQHGKQETDGRKRGSRGSHRAKSKSKETFLGTVKETFDAMKNSTKEFVRHHKEKIKQAKEAVKENLKKFSDSVKSTFRHFKDTTKNIFDEKGSKRFRAPKEAATEKTRTAYSYSSYSQQEAPNQNQNCRRPSAQRDGGREKPSHSEEIRKNANSYTYKAKSDCR---GTHSTRRVCSGMFECAGQEAISPVNKAS-PVRMNDFKQLIHWYLLNELETFHHWKELDQFISPFFPNGVFRHDQQLFADFVDDVKGYLKSIKEYRVE-DGNLEKLDGCIYRH-FGHVFALPFGP-------------------------RSVYIKPCYYNSF----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9ULG6-1", "uniprot_id": "CCPG1_HUMAN", "id": "Q9ULG6-1", "name": "Cell cycle progression protein 1", "aln": "MSENSSDSDSSCGWTVISHEGSDIEMLNSVTPTDSCEPAPECSSLEQEELQALQIEQG--ESSQNGTVLMEETAYPALEETSSTIEAEEQKIPEDSIYIGTASDDSDIVTLEPPKLEEIGNQEVVIVEEAQSSEDFNMGSSSSSQYTFCQPET--------------------------------VFSSQP----SDDESSS---DETSNQPSPAFRRRRARKKTVSASESE-----DRLVAEQETEPSKELSKRQF---SSGLNKCVILALVIAISMGFGHFYG---------TIQIQKRQQLVRKIHEDELNDMKDYLSQCQQEQESFIDYKS--LKENLARCWTLTEAEKMSFETQKTNLATENQYLRVSLEKEEKALSSLQEELNKLREQIRILEDKGTSTELVK-ENQKLKQHLEEEKQKKHSFLSQRETLLTEAKMLKRELERERLVTTALRGELQQLSGSQLHGKSDSPNVYTEKKEIAILRERLTELERKLTFEQQRSDLWERLYVEAKDQNGKQGTDGKKKGGRGSHRAKNKSKETFLGSVKETFDAMKNSTKEFVRHHKEKIKQAKEAVKENLKKFSDSVKSTFRHFKDTTKNIFDEKGNKRFGATKEAAE-KPRTVFSDYLHPQYKAPTENHHNRGPTMQNDGRKEKPVHFKEFRKNTNSKKCSPGHDCRE--NSHSFRKACSGVFDCAQQESMSLFNTVVNPIRMDEFRQIIQRYMLKELDTFCHWNELDQFINKFFLNGVFIHDQKLFTDFVNDVKDYLRNMKEYEVDNDGVFEKLDEYIYRHFFGHTFSPPYGP-------------------------RSVYIKPCHYSSL----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PAI3-1", "uniprot_id": "A0A8M1PAI3_DANRE", "id": "A0A8M1PAI3-1", "name": "", "aln": "MSESSSDTESSCGWTVISNEGSDIETLG---PDNAGECEDGVVSLPSHVPDATQVEESLGEPSLN---------LTLRAEATSEPVREAEAGAEEHVILCSSSDNSDIITLG--DAREAETEEEPVVKKTEEAGSEDLGSSSSSQYTFRESEK----------TWCWSVWGLSRCVWEYSSRSLSVFPVDPPAQRDDSNSSTEDDDDDETKASPVLRRRRVRRSSESGDPQEKHRRAEEVVEEIAAHPDPHAAQHDLGPVSSPLNKCILLALLIAISMGFGHFYG---------TVQIQERQRIVEKSRVIELD------VPCKRELDVIN-------KAQRRDLFEQLMQTKSRMESREKDLTAENQKLKISLEREEASLSALQEELLVLRGQIRELEDRGAGAQSIQSENQRLKGHLQEEKQKLRSFMSQREALMAEAQLLRKELEKERKTTENLKEEINR------------------KEETGELQAKLEELENKLKFEQQRSDLWERLYLEMKEERAKGDRDVKKT---------KIPKDGMLGKVKETFDAMKNSTKEFVHHQKEQIKKAKEAVKENLRKFSDSVKSTLRNFKNSATNVFS--HEKRFQE-------------------QQTFQQEHGNKR----ADDWQPQKPLYS---RKPTGDSSFNAERNTRKPGAQKTPPKGCSGVYDCAYQESMSLFNKAMEPIRADEFNELLHSYLQKEVGHFHHWRELESFINNFFHNGVFIHDQMLFTDFVSGVEDYLEEIIEYHGLSDDVFEDLDDYIYRHIFGETYIKYYGPSRPLEGPGSKVKAWRPCQRPQRKQQHQPRPRPHRAKKWSQHSGRDPNRQFADVKIELGPMPFDPKY", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***.***::********.:****** :. . : .. . .. *.* * . *:.* * .*: : : ::**:***:** . .* :* : : . ::********:* :.* **. : .*.:**: *: . :.**. **** *:.: * . .* : : * .*. . :::.: * ****::***:**:********* *:***: :: .* : **: ::* : * : : * :*:::.:*::**: *::***:** :**:***** *: *** ***:*:.:: :: *** ** :*: **** **: :* *: **::*:::**:*: .: *: *::: ::* *: :* ***.** *************:* *::..* * :* . .*: :**.****************:*:**:**:*********:*********:*:**:::.*:*. .*** : :: : * * :** : *: :.. . .. : * :: : ***:::** **::* .* . *:* ::*.:::: *: :*: * **.**:.**. ** **** *** *:***..*:.**..: **. *. :*.** **** **..: :** : :* . ", "identical_positions": 273, "similar_positions": 207, "identity": "31.24%" }, { "cls_id": "homologset.agr.MGI:1196423", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9UBC0-1", "uniprot_id": "HNF6_HUMAN", "id": "Q9UBC0-1", "name": "Hepatocyte nuclear factor 6", "aln": "---------------------------------------------------------------------------MNAQLTMEAIGELHG----------VSHEPVPAPADLLGG------------------------------------SPHARSSVAHRGSHLPPAHPRSMG-------------------------MASLLDGGSGGGD--------------------YHHHHRAPEHSLAGPLHPTMT-------------------------MACETPPG--------------------------------------MSMP----TTYTTLTPLQPLPPISTVSDKFPHHHHH--------------------------HHHHHHPHHHQRLAGNVSG--------------SFTLMRDERGLASMNNLYTPY-----------------------HKDVAG--MGQSLSPLSSSGLG------------------------------SIHNSQQG----LPHYAHPG---------------------------------AAMPTDK-----MLTPNGFEAHHPAMLGRHG-----------EQHLTP----------------TSAGMVPING-------LPPHHP-----------HAHLNAQGH--GQLLGTAREPN-------------------------PSVTG-------------------AQVSNG-------SNSGQMEEINTKEVAQRITTELKRYSIPQAIFAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAACK-------------------------------------------------------------------RKEQEHGKDRGNTPKKPRLVFTDVQRRTLHAIFKENKRPSKELQITISQQLGLELSTVSNFFMNARRRSLDKWQDEGSS----------------------------------------NSGNSSSSSSTCTKA-----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O08755-1", "uniprot_id": "HNF6_MOUSE", "id": "O08755-1", "name": "Hepatocyte nuclear factor 6", "aln": "---------------------------------------------------------------------------MNAQLTMEAIGELHG----------VSHEPVPAPADLLGG------------------------------------SPHARSSVGHRGSHLPPAHPRSMG-------------------------MASLLDGGSGGSD--------------------YHHHHRAPEHSLAGPLHPTMT-------------------------MACETPPG--------------------------------------MSMP----TTYTTLTPLQPLPPISTVSDKFPHHHHH--------------------------HHHHHHPHHHQRLAGNVSG--------------SFTLMRDERGLASMNNLYTPY-----------------------HKDVAG--MGQSLSPLSGSGLG------------------------------SIHNSQQG----LPHYAHPG---------------------------------AAMPTDK-----MLTPNGFEAHHPAMLGRHG-----------EQHLTP----------------TSAGMVPING-------LPPHHP-----------HAHLNAQGH--GQLLGTAREPN-------------------------PSVTG-------------------AQVSNG-------SNSGQMEEINTKEVAQRITTELKRYSIPQAIFAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAACK-------------------------------------------------------------------RKEQEHGKDRGNTPKKPRLVFTDVQRRTLHAIFKENKRPSKELQITISQQLGLELSTVSNFFMNARRRSLDKWQDEGGS----------------------------------------NSGSSSSSSSTCTKA-----------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P70512-1", "uniprot_id": "HNF6_RAT", "id": "P70512-1", "name": "Hepatocyte nuclear factor 6", "aln": "---------------------------------------------------------------------------MNAQLTMEAIGELHG----------VSHEPVPAPADLLGG------------------------------------SPHARSSVGHRGSHLPPAHPRSMG-------------------------MASLLDGGSGGSD--------------------YHHHHRAPEHSLAGPLHPTMT-------------------------MACETPPG--------------------------------------MSMP----TTYTTLTPLQPLPPISTVSDKFPHHHHH--------------------------HHHHHHPHHHQRLAGNVSG--------------SFTLMRDERGLASMNNLYTPY-----------------------HKDVAG--MGQSLSPLSGSGLG------------------------------SIHNSQQG----LPHYAHPG---------------------------------AAMPTDK-----MLTPNDFEAHHPAMLGRHG-----------EQHLTP----------------TSAGMVPING-------LPPHHP-----------HAHLNAQGH--GQLLGTAREPN-------------------------PSVTG-------------------AQVSNG-------SNSGQMEEINTKEVAQRITTELKRYSIPQAIFAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAACK-------------------------------------------------------------------RKEQEHGKDRGNTPKKPRLVFTDVQRRTLHAIFKENKRPSKELQITISQQLGLELSTVSNFFMNARRRSLDKWQDEGSS----------------------------------------NSGNSSSSSSTCTKA-----------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NJB5-1", "uniprot_id": "ONEC_DROME", "id": "Q9NJB5-1", "name": "Homeobox protein onecut", "aln": "MDSLNDIIDHQTFSQELVEDASEFITVGHHSERPSQSSQQPNSGQDLTMSMQDIISCPVKHRTCSASGSGSASGSDSVVMVIDALGQGNRQSAYQIVPQQLQQRNMPLPFGLLERDRQHMQHGREVNTSPVDFVSSDINLDGLTVDADVSQTDHSQETAVKQEQKLLIVQSKSQDQSHRRIRMLVDVSSVNSGLGVHVDDMDEISSDGVGCDDEGVTLSHQHLLEQEEQFGLTSHHPHLQPHTQIIHGLHQRSTHSEMGLDNGHGEVLSVIVHSQDSDKEDCEENDDGDAEGDLENEDDDERDSRSREQLLSHSSYQTLTSVNDRLSSPGFSQTSYATLTPIQPLPPISTMSEKFAYSGHISGGDSGDTDVNGDGAGGGVVEVGEVTNQSSEATGTVSISSGNATSSVCSNNDCSSFSALSMPIGSGHLGLGVLSGVQSPFSSYEKLSSMISPPPNNYLVSCDLHSSVSGRVINSSHLQLSHNGNKKESGTHEHTHRPADVNGGKFSYTGHISRGDSVDNDVNGEKFSFSDHISGGDSGDEDANREKFIYSDHISEGENGPDVNSGTNWLQMHSEREVRLHMPVPAELEARFHISSERRTRLNVPPARGSLSRHLAPNAPICPADWKADDWKHSNAGVVSLTADMPVVVSLTPTPPPLRDDSVSGIKQNERSSPGHREQYFLDKSQEPSSVVADQCSPGINGTPQSVCVIHQQSPSALGNGFQSSSQQAKVSSCASPKGTVSSGGAVSNRIANSSDMEEINTKDLAQRISAELKRYSIPQAIFAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMYKWLQEPEFQRMSALRMAAAQIPQRAPLSSGMSLGSATGPSGSTGTIPTDLDPHGGPTMIQNPLTNESDSSPASTPVTSVLVGSVVSCRRKEEPQIEQMPQPKKPRLVFTDLQRRTLQAIFKETKRPSKEMQVTIARQLGLEPTTVGNFFMNARRRSMDKWRDDDSKSTMHVAHSRQQQDEQQKDNAHTHSQSQIQDQNHSQNQAIHNSMSQDPYSNLHTTAMSPLGAFDEDADMDLELESHDFDLVDPDEHGDTNDPNGDML", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. :.::*:*: : :.:. :* * .** : *::.:. :: .:* .:.:* . * .: ..* * .* ** * *. .: ** * ** . :* * *:*:****:********:*:**.: * :: . . . :**.:. *:.: .. **. :..: :*: *..*:* :..* ** .* *:.*. :* :..: * * ::: * .* :**:. *: .:**:* :.**:*.:.. *.* * : . .: ** :*..::**. **. * . **.* :**.:*******::****::***********************************************:***************:**.: *:::* :: **********:*****:*****.******:*:**::***** :**.**********:***:*:... ** .... *. *.* ", "identical_positions": 219, "similar_positions": 152, "identity": "20.26%" }, { "cls_id": "homologset.agr.MGI:1196429", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZA45-1", "uniprot_id": "D3ZA45_RAT", "id": "D3ZA45-1", "name": "Autophagy-related protein 13", "aln": "METDLSSQDRKDLDKFIKFFALKTVQVIVQARLGEKICTRSSSSPTGSDWFNLAIKDIPEVTHEAKKAL---SGQLPAVGRSMCVEISLKTSEGDSMELEIWCLEMNEKCD-------------KEIKVSYTVYNRLSLLLKSLLAITRVTPAYRLSRKQG-HEYVILYRIYFGEVQLNGLGEGFQTVRVGTVGTPVGTLTLSCAYRINLAFMSTRQFERTPPIMGIIIDHFVDRPYPSSSPMHPCNYRTA-EDAGVAYPSVEDSQEVCTTSFSTSPPS-------------------------------------QLMVPGKEGGVPLAPNHPAHGAQADQERLVVHMPSDGTHCAATPSSSEDTETVSNSSEGRASPHDILETIFVRKVGAFVNKPINQVTLTSLDIPFAMFAPKNLELEDADPMVNPPDSPETTSPLHGSLHSEGSSGGSSGNAHDDFVMIDFKPAFSKDDILPMDLGTFYREFQNPPQLSSLSIDFGAQSMAEDLDSLPEKLAVHEKNVREFDAFVETLQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91YI1-1", "uniprot_id": "ATG13_MOUSE", "id": "Q91YI1-1", "name": "Autophagy-related protein 13", "aln": "METELSSQDRKDLDKFIKFFALKTVQVIVQARLGEKICTRSSSSPTGSDWFNLAIKDIPEVTHEAKKAL---SGQLPAVGRSMCVEISLKTSEGDSMELEIWCLEMNEKCD-------------KEIKVSYTVYNRLSLLLKSLLAITRVTPAYRLSRKQG-HEYVILYRIYFGEVQLNGLGEGFQTVRVGTVGTPVGTLTLSCAYRINLAFMSTRQFERTPPIMGIIIDHFVDRPYPSSSPMHPCNYRTA-EDAGVAYPSVEDSQEVCTTSFSTSPPSQLSSSRLSYQPAVLGLGSADLAYPVVFTAGLNTTHAHQLMVPGKEGGVTLAPSHPTHGAQADPERLVMHMPSDGTHCAATPSSSEDTETVSNSSEGRASPHDILETIFVRKVGAFVNKPINQVTVTSLDIPFAMFAPKNLELEDADPMVNPPESPETTSPLHGSLHSDGSSGGSGGSTHDDFVMIDFKPAFSKDDILPMDLGTFYREFQNPPQLSSLSIDFGAQSMAEDLDSLPEKLAVHEKNVREFDAFVETLQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75143-1", "uniprot_id": "ATG13_HUMAN", "id": "O75143-1", "name": "Autophagy-related protein 13", "aln": "METDLNSQDRKDLDKFIKFFALKTVQVIVQARLGEKICTRSSSSPTGSDWFNLAIKDIPEVTHEAKKAL---AGQLPAVGRSMCVEISLKTSEGDSMELEIWCLEMNEKCD-------------KEIKVSYTVYNRLSLLLKSLLAITRVTPAYRLSRKQG-HEYVILYRIYFGEVQLSGLGEGFQTVRVGTVGTPVGTITLSCAYRINLAFMSTRQFERTPPIMGIIIDHFVDRPYPSSSPMHPCNYRTAGEDTGVIYPSVEDSQEVCTTSFSTSPPSQLSSSRLSYQPAALGVGSADLAYPVVFAAGLNATHPHQLMVPGKEGGVPLAPNQPVHGTQADQERLATCTPSDRTHCAATPSSSEDTETVSNSSEGRASPHDVLETIFVRKVGAFVNKPINQVTLTSLDIPFAMFAPKNLELEDTDPMVNPPDSPETESPLQGSLHSDGSSGGSSGNTHDDFVMIDFKPAFSKDDILPMDLGTFYREFQNPPQLSSLSIDIGAQSMAEDLDSLPEKLAVHEKNVREFDAFVETLQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7SYE0-1", "uniprot_id": "ATG13_DANRE", "id": "Q7SYE0-1", "name": "Autophagy-related protein 13", "aln": "MDSDLSPQDKKDLDKFIKFFALKTVQVIVQARLGEKISTCSSSSPTGSDWFNLAIKDIPEVTHEAKKAL---AGQLPGIGRSMCVEISLKTSEGDSMELETWCLEMNEKCD-------------KDIKVSYTVYNRLSLLLKSLLAITRVTPAYKLSRQQG-HDYVILYRIYFGDVQLTGLGEGFQTVRVGIVGTPIGTITLSCAYRTNLALVSSRQFERTGPIMGIIIDHFVERPFTNMAHTHPCSYRAPGEDDGGTYAGIEDSQEVCTTSFSTSPPSQLYSSRLSYQTPPLG--TVDLCHPTACTG---AAHPHQMVVPGKDGGIPQVPAQPNHGTGAEQGRIPSCPTGQPPQLPPPTSCSSEVKTVS--------PSDVLETTFTRKVGAFVNKATTQVTTTGLDLPFAAFAPRSYDMEENDPMVHPPPSPIPSSPLQGSLHSNNSS-HSGGQPNDDFVMVDFKPAFSKDDLLPMDLGTFYREFQNPPQLASLSIDVSAQSMAEDLDSLPEKLAVYEKNIDEFDAFVDTLQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VHR6-1", "uniprot_id": "ATG13_DROME", "id": "Q9VHR6-1", "name": "Autophagy-related protein 13 homolog", "aln": "MSAQRLNAAERDLEKFIKFLVLKSTQVVVQSRLGEKMQTQCN-PLAGSDWFNIAVQDHPEVLDETKRALNLKTGESILQRLPLCVEISLKTTEGDQMVLEVWSLDLLQPQNGASPATNDLNPEGQTLKAAHAIYNRMGIMLKSLISLTRTTPAYKLSRRQCPDSYGIFYRIYVDRPQVHTLGEGHKHVKIGQLSTIVGSLVMSVAYRTKLTISPTAAQSESNTIM-LKSDHFRPATDANTPGNQQQTQNGTVVAKKLGLGALNPAQGTADRRFIDIEKP-LRPGAFTDMGKLKQYTEDDFVLPETPPFEWLLRGRGSVESLNRLDNNSVASVNISNNNNSTQDSKFNQISNLNNNSAGFKSFEKNSENSVSPIKSLLIPASATATYRHHSEPSLQPPPDDDNLLKELHFPFASPTSHVNDLAKFYRECYHAPPLKGLNELQAEISSISSTPPASSGS-GGVAACGPTAAATAIATSSADASAMDDLSRQLEQFETSLEDYDKLVSQFGLTGSSSTGSRSSGGLQMSN-------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.:: .:**:*****:.**:.**:**:*****: * .. . :******:*::* *** .*:*:** :*: .:********:***.* ** *.*:: : : : :*.::::***:.::****:::**.****:***:* ..* *:****.. *: ****.: *::* :.* :*::.:* *** :*:: .: ..: .** : *** . .. . : . . . .:: :* .. * . .: .: .. . .. : :. : .. : . * ..: :. * . * :. :: . : . *.:*** :.: :: . . . . *:..: * .*: :.. . .... . ..* : . * .:: :: *: : * . .* . ... : . .: : ", "identical_positions": 112, "similar_positions": 171, "identity": "20.97%" }, { "cls_id": "homologset.agr.MGI:1196431", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D2J0Y4-1", "uniprot_id": "CJ090_MOUSE", "id": "D2J0Y4-1", "name": "(E2-independent) E3 ubiquitin-conjugating enzyme FATS", "aln": "-----------------------------------------------------------------------------MISPVVISRLIDEKKSMENGAILPQ--AIAQPQLCPTKPALARRDGVSMHRRFALSPDRLGILTPSDDQGLETEPLSTGDNLGKGSHSGFSSITITARRVGPPASSLVWDTFRDPLCPKCKAKDALFQEPPVLAGDAHLCQHNRPFTCTESPSNGSVEGMKVFQAHSRLSARQDYWVTHTNDNEDSFSSDNSPSRKVPLVFSSCVHFRVSQQCPNAIYYLDKSLSVPLERPQIASPKMHRSVLSLSLRCSSHQLTADGVDSSANGEPISTALSQELSEGKQDLLGPQWGQ-PQGGHWKESPALVPVHLGSGTCPRTGSPPLENVKFADVGRNQVPVRKEKEDHAT-CTSSSHTNQLSIHIPGWSYR-AETKVLSGS-KKQQQEAQRTLPAFPVGQKTIKHFPPEGDSSPSSDGQPSILSESNERQHPYFMIPRVPLPGFYCPLQTGCASLQEDGAVQIETHFPK-DYTCCDLVVKLKECEKNEDPTVTPEPSPATPSPSTPEGAQSSDPSEDSYEP--LLASSMTLQEALEVHRPQFISRSQERLQKLKRMVQQRKTQQKESLGQKQSLLPVRANKKQFTIPHPLSDNLFKPKERCISEKEMHMRSKRIYNNLPEVKKKKEEQKKRMILQSNRLRAEVFKKQLLDQLLQRNAV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZKF8-1", "uniprot_id": "A0A8I5ZKF8_RAT", "id": "A0A8I5ZKF8-1", "name": "", "aln": "MPANPPGEVDAVRPTFQITAFSTSLKNHVMVTDLVKRNWLPSQRRAKVCFIHMCPGLKVTEQPVSGYEETLASQNTRMISPVVISRLIDEKKSMENGAVLSQ--AIAQPQLCPPKPASARPGGVSKHRPFALSPDGLGILAPSDEQGLEIEPLSTGDNLGKGPRSGFSSITITARRVGPPASNLVWDTFRDPLCSKCGTKDAGFQDPPVLASGAHLCQHNRPYSYTEFPSNGSVEGLKVTQAHSRLCARQDYWVTHADDNEDSFSSDNSPSRKVPLVFSSCVHLRVSQQCPSAIYYLDKSLSVPLEQPQIASPKMHRSVLSLSLRCSSHQLTADGVDSPANGEPISRALSQELSEGKQDLLGSQWGQ-PQEGHWKESPALVPVHLGSGTCPQTGSPPLENVKFADVGRNQVPVHKEKEDHAT-CTNSSHSNQLSIHIPGWSYR-AETKVLSRS-KKQQHQAQRTLSAFPVGQKPIKHFPPDGDSLPSNDGQPNILSESHKRQHSYFMTPKVPLSGFFCPLQTVCASLQEDDAIQIETQFPK-DYTCCDLVVKLKDCEKHEDPTVTPEPSPATPSPATRAGPQSSGPLEDSFEP--LMASSMTLQEALEVHRPQFISRSQERLQKLKHMVQQRKTQQKESLGQKQSLLPVRANKKQFTIPHPLSDNLFKPKERCISEKEMHMRSKRIYNNLPEVRKKKEEQKKRVILQSNRLRAEVFKKQLLDQLLQRNAV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96M02-1", "uniprot_id": "CJ090_HUMAN", "id": "Q96M02-1", "name": "(E2-independent) E3 ubiquitin-conjugating enzyme FATS", "aln": "----------------MLKLSGEGLRDSYHS------------RRDQIALKNLQS--DVTEAKSDFTKETLASQNTKMISSIVISQMIDENKSRENRASLPLPCAIAQSRAHHAKQSLANRSGVNIHRAFALLPGRLGIPAPSDERGPEAELPPKEERPCGGPRRGFASITITARRVGPPARALVWGTAGDSLCPKCRAEDTLFQAPPALANGAHPGRHQRSFACTEFSRNSSVVRLKVPEAHTGLCERRKYWVTHADDKETSFSPDTPLSGKSPLVFSSCVHLRVSQQCPDSIYYVDKSLSVPIEPPQIASPKMHRSVLSLNLNCSSHRLTADGVDGLVNREPISEALKQELLEGDQDLVGQRWNPGLQESHLKETPSLRRVHLGTGACPWSGSFPLENTELANVGANQVTVRKGEKDHTTHCHASDHANQLSIHIPGWSYRAVHTKVFSGSSKRQQGEVCMTVSAPPVEQKPTRHFLPIGDSSPSDDCLSRDLSEPTERRHQSFLKPRILFPGFLCPLQDVCASLQEDNGVQIESKFPKGDYTCCDLVVKIKECKKSEDP-TTPEPSPAAPSPAPRDGAGSPGLSEDCSESQQTPARSLTLQEALEVRKPQFISRSQERLKKLEHMVQQRKAQRKEDLRQKQSLLPIRTSKKQFTIPHPLSDNLFKPKERCISEKEMHMRSKRIYDNLPEVKKKKEEQRKRVILQSNRLRAEVFKKQLLDQLLQRNAV", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ***.:***::***:** ** * *. ****.: .* : *. .**. ** *** *. *** :***::* * * .. :. *.: **:************* ***.* *.**.** ::*: ** **.**..** :*:*.:: ** . *.** :** :**: *. *:.*****::*:* ***.*.. * * *********:*******.:***:*******:* ***************.*.****:*******. .* **** **.*** **.***:* :*. * .* **:*:* ****:*:** :** ****.::*:** ***.*:* ::**:* * *.*:************* ..***:* * *:** :. *:.* ** **. :** * *** **.* . ***. :*:* *: *:: :.** **** *******..:***::*** **********:*:*:* *** .*******:***:. *. *.. **. *. * *:********::***********:**::******:*:**.* *******:*:.***********************************:*****:******:**:**************************", "identical_positions": 410, "similar_positions": 137, "identity": "56.16%" }, { "cls_id": "homologset.agr.MGI:1196437", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6PCN7-1", "uniprot_id": "HLTF_MOUSE", "id": "Q6PCN7-1", "name": "DNA-dependent ATPase/E3 ubiquitin-protein ligase HLTF", "aln": "---------------------MSYTFTRGPVWKYSQSVQYGSHENIPRLSYSTFLPHFEFQDIIPPDDFLTSDE---------------------EQDLVLFGTMRGQVVGLRYYTGVVNNNEMVALQREPNNPYDKNAIKVNNVNGNQVGHIKREIAAAVAYI-MDNKLAQVEGVVPFGASNTFTMPLYMTFWG------KEENRNVVLEQLKKHGFKLGPTPKTLGSSLENAWGSGRAGPSYSRPAHVAVQMTTDQLKTEFDKLFEDLKEDDRTVEMEP--AEAIETPLLPHQKQALAWMIARENSKELPPFWEQRNDLYYNTITNFSVKERPENVHGGILADDMGLG------KTLTAIAVILT------NFDDGRPLLSKRGK-KNHPGKEY--KDETIKRRGSNMDKKEDGHS-ESSTCGEEPSISGTPEKSSCTLSQLSSVCPKRRKISVQYIESSDSEEIETSELPQKMKGKLKNVQLNTKSRVK-GSSKVKEDSKF--ALTFFAS----------------------------------------------ATQRKMLKKGMSMMECSEACDTGERTRATLIICPLSVLSNWIDQFGQHVKSEVHLNFYVYYGPDRIRDSAWLSKQD----IILTTYNILTHDYG------------TKDDSPLHSIKWLRVILDEGHAIRNPNAQQTKAVLELEAERRWVLTGTPIQNSLKDLWSLLSFLKLKPFID-------------------------------REWWYRIIQRPVTTGDEGG-----LRRLQSLIKNITLRRTKTSK-IKGKPVLELPERKVFIQHITLSEEERKIYQSVKNEGKAAIGRYFTEGTVLAHYADVLGLLLRLRQICCHTHLLTN------GMSSSGPSRSDTPEELRKMLIEKMKIILSSGSDE----------------------ECAICLDS---LTFPVITHCAHVFCKPCICQVIH---SEQPHAKCPLCRNEIHGDNLLECPPEELACD------SDKESSMEWKSSSKINALMHALIELRTKDPNIKSLVVSQFTTFLSLIETPLKASG----FVFTRLDGSMAQKKRVESIQRFQNTEAGSPTIMLLSLKAGGVGLNLCAASRVFLMDPAWNPAAEDQCFDRCHRLGQKQEVIITKFIVKDSVEENMLKIQNTKRDLAAGAFGTKKTDANDMKQAKINEIRTLIDL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2JVH5-1", "uniprot_id": "A0A0G2JVH5_RAT", "id": "A0A0G2JVH5-1", "name": "", "aln": "---------------------MSWKFKRDSVWKYSQSAQYGAHENIPRLSYPPFFPRFEFQDIIPPDDFQTSDE---------------------ELDLVLFGTMRGQVVGIRYYTGVVNNNEMVALEREPNNPYDKNAIKVNNVNGNQVGHLKRDLAAALAYI-MDNKLAQVEGVVPFGASNTFTMPLHMTFWG------KEENREVVLDHLKKHGFKLGPTPKTVGSSLENTWGSGRAGPSYSRPVHVAVQMTTEQLKTEFDKLFEDLKEDDRTIEMEP--AEAVETPLLPHQKQALAWMIARENSKELPPFWELRNDLYYNTITNFSVKERPENVHGGILADDMGLG------KTLTAIAVILT------NFDDGRPLLGKRGK-ESHPGKEY--KDETVKLRGSNTNKTTDGHS-EPSACSEEPSISDVSEKS--NVSDLFSFFSKRRKISVQSTESSESEEIETSKLSQKMKGKLKNTQLDTKSKVK-GSSKIKEDTQFALALTYFGP----------------------------------------------ATKKKMLKKGTSVMESSKKCDTGERTRTTLIICPLSVLSNWIDQIGQHIKSEVDLNLYVYYGPDRIRDSTWLSKQD----IILTTYNILTHDYG------------TKDNSPLHSIKWLRVILDEGHAIRNPNAQQTKAVLELEAERRWVLTGTPIQNSLKDLWSLLSFLKLKPFTD-------------------------------REWWHRIIQRPVTTGDEGG-----LRRLQSLIKSITLRRTKTSK-IKGKPVLELPERKVFIQHITLSVEERKIYQSVKNEGKATIARYFTEGTVLAHYADVLGLLLRLRQICCHVHLPTN------GTSSSDPSRSDTPEELRKMLVTKMKLILSSGSDE----------------------ECSICLDS---LTFPVITHCAHVFCKPCICQVIQ---REQPHAKCPLCRSNIHGHNLLECPPEELACD------SDNKSDMEWTSSSKINALMNALIELRTKDPNIKSLVVSQFTTFLSLIETPLKASG----FVFTRLDGSMAQKKRVESIQCFQNTDAGSPTIMLLSLKAGGVGLNLCAASRVFLMDPAWNPAAEDQCFDRCHRLGQKQEVIITKFIVKDSVEENMLKIQNMKRELAAGAFGTKKTDADEMKQAKINEIRTLIDL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q14527-1", "uniprot_id": "HLTF_HUMAN", "id": "Q14527-1", "name": "DNA-dependent ATPase/E3 ubiquitin-protein ligase HLTF", "aln": "---------------------MSWMFKRDPVWKYLQTVQYGVHGNFPRLSYPTFFPRFEFQDVIPPDDFLTSDE---------------------EVDSVLFGSLRGHVVGLRYYTGVVNNNEMVALQRDPNNPYDKNAIKVNNVNGNQVGHLKKELAGALAYI-MDNKLAQIEGVVPFGANNAFTMPLHMTFWG------KEENRKAVSDQLKKHGFKLGPAPKTLGFNLESGWGSGRAGPSYSMPVHAAVQMTTEQLKTEFDKLFEDLKEDDKTHEMEP--AEAIETPLLPHQKQALAWMVSRENSKELPPFWEQRNDLYYNTITNFSEKDRPENVHGGILADDMGLG------KTLTAIAVILT------NFHDGRPLPIERVK-KNLLKKEYNVNDDSMKLGGNNTSEKADGLSKDASRCSEQPSISDIKEKSKFRMSELSSSRPKRRKTAVQYIESSDSEEIETSELPQKMKGKLKNVQSETKGRAKAGSSKVIEDVAFACALTSSVP----------------------------------------------TTKKKMLKKGACAVEGSKKTDVEERPRTTLIICPLSVLSNWIDQFGQHIKSDVHLNFYVYYGPDRIREPALLSKQD----IVLTTYNILTHDYG------------TKGDSPLHSIRWLRVILDEGHAIRNPNAQQTKAVLDLESERRWVLTGTPIQNSLKDLWSLLSFLKLKPFID-------------------------------REWWHRTIQRPVTMGDEGG-----LRRLQSLIKNITLRRTKTSK-IKGKPVLELPERKVFIQHITLSDEERKIYQSVKNEGRATIGRYFNEGTVLAHYADVLGLLLRLRQICCHTYLLTN------AVSSNGPSGNDTPEELRKKLIRKMKLILSSGSDE----------------------ECAICLDS---LTVPVITHCAHVFCKPCICQVIQ---NEQPHAKCPLCRNDIHEDNLLECPPEELARD------SEKKSDMEWTSSSKINALMHALTDLRKKNPNIKSLVVSQFTTFLSLIEIPLKASG----FVFTRLDGSMAQKKRVESIQCFQNTEAGSPTIMLLSLKAGGVGLNLSAASRVFLMDPAWNPAAEDQCFDRCHRLGQKQEVIITKFIVKDSVEENMLKIQNKKRELAAGAFGTKKPNADEMKQAKINEIRTLIDL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BAK6-1", "uniprot_id": "A0A8M2BAK6_DANRE", "id": "A0A8M2BAK6-1", "name": "", "aln": "-----------------------MQSSSSSTASSSTPPRYAFIDFMDVG--STMTLSQELANLT--EDAGQELE---------------------AEGNVLFGSIQGLIVGLRYYTGAVNKGEMVSLVREPHNPYDRNAVMVANVYGSQVGHIKKELAAAMAYI-MDNKLARVEGIVPYGEKNKFSMPVILTFWG------KEENREVVNNLMIGFGFNLDFR----GGSSQTSLGRDLLGLS---TKLSAIPLSAEELKNAFDKLFDDLMED-KTKEMEP--AEAVCTPLLSHQKQALSWMSSRENSNDLPPFWEENKGLYFNVLTNFAVKKRPEKVLGGILADDMGLG------KTLTTIALIVS------NFHNGKPLPLEKCKGPSMPSAKR--KQATSKEKGVDSEESQESMG----------------------------LSPLKRLHDDTVRENG----------PQKKTKTTKKKSANTKKAVV-----LLDDVEFAAALECSSSQ--------------------------------------------VVPSKKCVKKSSVPSEIS----AGSVARATLIVCPLSVLSNWLDQFEQHIRTDVTVKVYLYYGSERNRSVSLLSEQD----VVLTTYNVLSSDFG------------NKASSPLHNVKWLRVVLDEGHVVRNPNALQSKAVLELQSERRWILSGTPIQNSLKDLFMLLSFLKLKPFDV-------------------------------KEWWSRIIQRPVTMGDRVG-----LKNLQALVKGITLRRTKNSK-VGGRTLVQLPERRVFVQYVTLSGMEREKYERVKGEGKNIVGRYFQEGTFMANYADVLTILMRLRQCCCHPSLVGN------YTAADVPG---TPSELRERLIQKITLVLNSGSDE----------------------ECAICLDS---LRQPVITYCAHVFCRPCICEVIR---SEKEQAKCPLCRAQIKTKELVEYPGEQAETR------SDTG--ENWRSSSKALALMSNLLKLRNEDPTVKSMVVSQFTGFLDVLEVALREYG----FSFTRLDGSLIQRARAKAIEDFQDSTPGSPTIMLLSLKAGGVGLNLTAASQVFVMDPAWNPAAEDQCVDRCHRLGQSRDVVITKFIVKDSVEENMVKIQKKKQELVDKAFGVK--NSQDAKQARIDDIRALMEL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P31244-1", "uniprot_id": "RAD16_YEAST", "id": "P31244-1", "name": "DNA repair protein RAD16", "aln": "---------------------------------------------MQEGGFIRRRRTRSTKKSVNYNELSDDDT---------------------AVKNSKTLQLKGNSENVNDSQDEEYRDDATLVK----SPDDDDKDFIIDLTGSDKERTATDENTHAIKN-DNDEIIEIKEERDVSDDDEPLTKKRKTTAR------KKKKK------------------------------TSTKKKSPKVTPYERNTLRLYEHHPELRNVFTDLKNAPPYVPQRSKQPDGMTIKLLPFQLEGLHWLISQEES----------------------------IYAGGVLADEMGMG------KTIQTIALLMN------DLTKS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PSLVVAPTVALMQWKNEIEQHTKG--QLKIYIYHGASRTTDIKDLQGYD----VVLTTYAVLESVFRKQNYGFRRKNGLFKQPSVLHNIDFYRVILDEAHNIKDRQSNTARAVNNLKTQKRWCLSGTPLQNRIGEMYSLIRFLNINPFTKYFCTKCDCASKDWKFTDRMHCDHCSHVIMQHTNFFNHFMLKNIQKFGVEGPGLESFNNIQTLLKNIMLRRTKVER-ADD---LGLPPRIVTVRRDFFNEEEKDLYRSLYTDSKRKYNSFVEEGVVLNNYANIFTLITRMRQLADHPDLVLK------RLN---------------------NFPGDDIGVV----------------------ICQLCNDE---AEEPIESKCHHKFCRLCIKEYVESFMENNNKLTCPVCHIGLSIDLSQPALEVDLDSFKKQSIVSRLNMSGKWQSSTKIEALVEELYKLRSNKRTIKSIVFSQFTSMLDLVEWRLKRAG----FQTVKLQGSMSPTQRDETIKYFMN--NIQCEVFLVSLKAGGVALNLCEASQVFILDPWWNPSVEWQSGDRVHRIGQYRPVKITRFCIEDSIEARIIELQEKKANMIHATINQDEAAISRLTPADLQFLFNN---", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P32849-1", "uniprot_id": "RAD5_YEAST", "id": "P32849-1", "name": "DNA-dependent ATPase/E3 ubiquitin-protein ligase RAD5", "aln": "MSHIEQEERKRFFNDDLDTSETSLNFKSENKESFLFANSHNDDDDDVVVSVSDTTEGEGDRSIVPVRREIEEEGQNQFITELLRIIPEMPKDLVMELNEKFGSQEEGLSLALSHYFDHNSGTSISKIPSSPNQLNTLSDTSNSTLSPSSFHPKRRRIYGFRNQTRLEDKVTWKRFIGALQVTGMATRPTVRPLKYGSQMKLKRSSEEISATKVYDSRGRKKASMASLVRIFDIQYDREIGRVSEDIAQILYPLLSSHEISFEVTLIFCDNKRLSIGDSFILQLDCFLTSLIFEERNDGESLMKRRRTEGGNKREKDNGNFGRTLTETDEELESRSKRLALLKLFDKLRLKPILDEQKALEKHKIELNSDPEIIDLDNDEICSNQVTEVHNNLRDTQHEEETMNLNQLKTFYKAAQSSESLKSLPETEPSRDVFKLELRNYQKQGLTWMLRREQEFAKAASDGEASETGANMINPLWKQFKWPNDMSWAAQNLQQDHVNVEDGIFFYANLHSGEFSLAKPILKTMIKGGILSDEMGLGKTVAAYSLVLSCPHDSDVVDKKLFDIENTAVSDNLPSTWQDNKKPYASKTTLIVVPMSLLTQWSNEFTKANNSP-DMYHEVYYGGNVSSLKTLLTKTKTPPTVVLTTYGIVQNEWTKHSKG-RMTDEDVNISSGLFSVNFYRIIIDEGHNIRNRTTVTSKAVMALQGKCKWVLTGTPIINRLDDLYSLVKFLELDPWRQ-------------------------------INYWKTFVSTPFESKNYKQ----AFDVVNAILEPVLLRRTKQMKDKDGKPLVELPPKEVVIKRLPFSKSQDLLYKFLLDKAEVSVKSGIARGDLLKKYSTILVHILRLRQVCCHPGLIGSQDENDEDLSKNNKLVTEQTVELDSLMRVVSERFDNSFSKEELDAMIQRLKVKYPDNKSFQSLECSICTTEPMDLDKALFTECGHSFCEKCLFEYIEFQNSKNLGLKCPNCRNQIDACRLLALVQTNSNSKN-----LEFKPYSPASKSSKITALLKELQLLQDSSAGEQVVIFSQFSTYLDILEKELTHTFSKDVAKIYKFDGRLSLKERTSVLADFAVKDYSRQKILLLSLKAGGVGLNLTCASHAYMMDPWWSPSMEDQAIDRLHRIGQTNSVKVMRFIIQDSIEEKMLRIQEKKR-TIGEAMDTDEDERRKRRIEEIQMLFE----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . .* : . . : . . : .. :::: . . . *.... * . : : . :* * . : :: : :. : :. . * *.: : *:: : :. :: .. .:*:: * * :* ::: : . : :*:* . * . ::**** :: : : * *..: : *:::**.* ::: : ::** *: : :* *:***: * : ::: *: **::.*: ::: : . . : :::::: : ***** : . : ** : * :: :. : *. : ... . .* .: :*: :: : *:** . * * . .. . * :* . .: : * * **. *: : :. :: .** *: : : .*:* **: * *: .. : ::.***: *.::* * :::* : * . : * ::*:*******.*** **:.:::** *.*: * *. ** **:** . * : :* ::**:* .::.:*: * ::. . :: : ", "identical_positions": 111, "similar_positions": 211, "identity": "9.13%" }, { "cls_id": "homologset.agr.MGI:1196439", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O95931-1", "uniprot_id": "CBX7_HUMAN", "id": "O95931-1", "name": "Chromobox protein homolog 7", "aln": "MELSAIG---------------EQVFAVESIRKKRVRKGKVEYLVKWKGWPPKYSTWEPEEHILDPRLVMAYEEKEERD-----RASGYRKRGPKPKRLLLQRLYSMDLRSSHKAKGKEKLCFSLTCP---------LGSGSPEGVVKAGAPELVDKGPLVPTLPFPLRKPRKAHKYLRLSRKKFPPRGPNLESHSHRRELFLQEPPAPDVLQAAGEWEPAAQ----PPEEEADADLAE----------------------GPP-----------------------------------------------------------------------------------------------------------PWTPALP--SSEVTVTDITANSITVTFREAQAAEGFFRDRSGKF------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P60889-1", "uniprot_id": "CBX7_RAT", "id": "P60889-1", "name": "Chromobox protein homolog 7", "aln": "MELSAIG---------------EQVFAVESIRKKRVRKGKVEYLVKWKGWPPKYSTWEPEEHILDPRLVMAYEEKEEKD-----RASGYRKRGPKPKRLLLQ------------------------------------------------------------------------------------------------------ESAAPDVLQATGDWEPVEQ----PPEEEAEADLTN----------------------GPP-----------------------------------------------------------------------------------------------------------PWTPMLP--SSEVTVTDITANSVTVTFREAQAAEGFFRDRSGKL------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VDS3-1", "uniprot_id": "CBX7_MOUSE", "id": "Q8VDS3-1", "name": "Chromobox protein homolog 7", "aln": "MELSAIG---------------EQVFAVESIRKKRVRKGKVEYLVKWKGWPPKYSTWEPEEHILDPRLVMAYEEKEERD-----RASGYRKRGPKPRRLLLQ------------------------------------------------------------------------------------------------------ESAAPDVVQTPGDWEPMEQ----APEEEAEADLTN----------------------GPP-----------------------------------------------------------------------------------------------------------PWTPTLP--SSEVTVTDITANSVTVTFREAQAAEGFFRDRNEKL------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M1N5K1-1", "uniprot_id": "A0A8M1N5K1_DANRE", "id": "A0A8M1N5K1-1", "name": "", "aln": "MELSSIG---------------EQVFAVESITKKRIRKGNVEYLLKWQGWSPKYSTWEPEDNILDPRLVLAFEEKAEKD-----RALAYKKKGLRPRQVILRNIYPMDLRSAHKVPDKPSPRIRLSLTRSMSTEVDQNGRRYRDSVVYRRLKNRYKNRQCRSRLFEGIKPSKQTMRHPLPAKDCTENAWNEDEQKRKVKKMRKDEENTTQVHQDIPSGQEMSEGYNSSAEQESEITIKEDENCSSIFDQEEKPSEDTGTAIGAPESSTITDTEKNEPVTNTAGDEDCVWVSHDTTNTDQSLHKCTKSGAEEGVFDRVQNRPSVIEVRLSARCGQEEVRESAEVGSSEAKDKEGIDAEVTAEFQVPIDQLQTPVTTAVH--PGKVIVTQVTINSLTVTFKEAMTAEGFFSECGLEV------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P26017-1", "uniprot_id": "PC_DROME", "id": "P26017-1", "name": "Polycomb group protein Pc", "aln": "MTGRGKGSKGKLGRDNATDDPVDLVYAAEKIIQKRVKKGVVEYRVKWKGWNQRYNTWEPEVNILDRRLIDIYEQTNKSSGTPSKRGIKKKEKEPDPEPESEEDEYTFTENDVDTHQATTSSATHDKES----------KKEKKHHHHHHHHHHIKSERNSGRRSESPLTHHHHHHHHESKRQRIDHSSSSNSSFTHNSFVPEPDSNSSSSEDQPLIGTKRKAEVLKESGKIGVTIKTSPD---------------------GPTIKPQPTQQVTPSQQQPFQDQQQAEKIASEAATQLKSEQQATPLATEAINTTPAESGAEEEEVANEEGNQQAPQVPSENNNIPKPCNNLAINQKQPLTPLSPRALPPRFWLPAKCNISNRVVITDVTVNLETVTIRECKTERGFFRERDMKGDSSPVA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . * : *:*.*.* :**::** *** :**:** :*.***** :*** **: :*:. : . *. ::: *. . . :.. * : : . : *.. . ...* :*::* * ***::*. : .*** : . : ", "identical_positions": 44, "similar_positions": 50, "identity": "10.45%" }, { "cls_id": "homologset.agr.MGI:1196450", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5U220-1", "uniprot_id": "TM254_RAT", "id": "Q5U220-1", "name": "Transmembrane protein 254", "aln": "MGTATGASYFQRGSLFWFTVIAVSFSYYTWVVFWPQSIPYQSLGPLGPFTKYLVDHYHTLLRNGYWLAWLVHVGESLYALVLCRRKGITDSQAQLLWFLQTFLFGVASLSILFAYRPK-HQKHN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P0DN89-1", "uniprot_id": "TM254_MOUSE", "id": "P0DN89-1", "name": "Transmembrane protein 254", "aln": "MGTATGAGYFQRGSLFWFTVITVSFGYYTWAVFWPQSIPYQSLGPLGPFTKYLVDHYHTFLRNGYWLAWLIHVGESLYALVLCKRKGITDVQAQLLWFLQTFLFGVASLSILIAYRSK-RQKHN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TBM7-1", "uniprot_id": "TM254_HUMAN", "id": "Q8TBM7-1", "name": "Transmembrane protein 254", "aln": "MATAAGATYFQRGSLFWFTVITLSFGYYTWVVFWPQSIPYQNLGPLGPFTQYLVDHHHTLLCNGYWLAWLIHVGESLYAIVLCKHKGITSGRAQLLWFLQTFFFGIASLTILIAYKRK-RQKQT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32U5S7-1", "uniprot_id": "A0AB32U5S7_DANRE", "id": "A0AB32U5S7-1", "name": "Transmembrane protein 254", "aln": "MAKTDGSSFFRRTSVFWMLTVSLALAFYTWTVFWPRDVPYGSLGPLGALANYMVEQHYTVMYYGWFFTWLIHLCEAMFALKLCSDKGIFSSSARLLWFVQTFLFGFASLGLLLKYKPDGRHKRH", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*..: *: :*:* *:**: .:::::.:***.****:.:** .*****.:::*:*::::*.: *::::**:*: *:::*: ** *** . *:****:***:**.*** :*: *: . ::*: ", "identical_positions": 51, "similar_positions": 54, "identity": "41.13%" }, { "cls_id": "homologset.agr.MGI:1196453", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XHZ6-1", "uniprot_id": "KLHL7_RAT", "id": "Q5XHZ6-1", "name": "Kelch-like protein 7", "aln": "MATSGVEKSS--KKKTEKKLAAREEAKLLAGFMGVMNNMRKQRTLCDVILMVQERKIPAHRVVLAAASHFFNLMFTTNMLESKSFEVELKDAEPDIIEQLVEFAYTARISVNSNNVQSLLDAANQYQIEPVKKMCVDFLKEQVDASNCLGISVLAECLDCPELKSTADDFIHQHFTEVYKTDEFLQLDVKRVTHLLSQDTLTVRAEDQVYDAAVRWLKYDEPNRQPFMVDILAKVRFPLISKNFLSKTVQAEPLIQDNPECLKMVISGMRYHLLSPEDREELAGGTRPRRKKHDYRIALFGGSQPQSCRYFNPKDYSWTDIRCPFEKRRDAACVFWDNVVYILGGSQLFPIKRMDCYNVVKDSWYSKLGPPTPRDSLAACAAEGKIYTSGGSEVGNSALYLFECYDTRTESWHTKPSMLTQRCSHGMVEANGLIYVCGGSLGNNVSGRVLSSCEVYDPATETWTELCSMIEPRKNHGLVFVKDKIFAVGGQNGLGGLDNVEYYDIKLNEWKMVSPMPWRGVTVKCAAVGSVIYVLAGFQGVGRLGHILEYNTETDKWVANSKVRAFPVTSCLICVVDTCGANEETLET------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BUL5-1", "uniprot_id": "KLHL7_MOUSE", "id": "Q8BUL5-1", "name": "Kelch-like protein 7", "aln": "MATSGVEKSS--KKKTEKKLAAREEAKLLAGFMGVMNNMRKQRTLCDVILTVQERKIPAHRVVLAAASHFFNLMFTTNMLESKSFEVELKDAEPDIIEQLVEFAYTARISVNSNNVQSLLDAANQYQIEPVKKMCVDFLKEQVDASNCLGISVLAECLDCPELKATADDFIHQHFTEVYKTDEFLQLDVKRVTHLLSQDTLTVRAEDQVYDAAVRWLKYDEPNRQPFMVDILAKVRFPLISKNFLSKTVQAEPLIQDNPECLKMVISGMRYHLLSPEDREELAGGTRPRRKKHDYRIALFGGSQPQSCRYFNPKDYSWTDIRCPFEKRRDAACVFWDNVVYILGGSQLFPIKRMDCYNVVKDSWYSKLGPPTPRDSLAACAAEGKIYTSGGSEVGNSALYLFECYDTRTESWHTKPSMLTQRCSHGMVEANGLIYVCGGSLGNNVSGRVLSSCEVYDPATETWTELCSMIEPRKNHGLVFVKDKIFAVGGQNGLGGLDNVEYYDIKLNEWKMVSPMPWRGVTVKCAAVGSVIYVLAGFQGVGRLGHILEYNTETDKWIANSKVRAFPVTSCLICVVDTCGANEETLET------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IXQ5-1", "uniprot_id": "KLHL7_HUMAN", "id": "Q8IXQ5-1", "name": "Kelch-like protein 7", "aln": "MAASGVEKSS--KKKTEKKLAAREEAKLLAGFMGVMNNMRKQKTLCDVILMVQERKIPAHRVVLAAASHFFNLMFTTNMLESKSFEVELKDAEPDIIEQLVEFAYTARISVNSNNVQSLLDAANQYQIEPVKKMCVDFLKEQVDASNCLGISVLAECLDCPELKATADDFIHQHFTEVYKTDEFLQLDVKRVTHLLNQDTLTVRAEDQVYDAAVRWLKYDEPNRQPFMVDILAKVRFPLISKNFLSKTVQAEPLIQDNPECLKMVISGMRYHLLSPEDREELVDGTRPRRKKHDYRIALFGGSQPQSCRYFNPKDYSWTDIRCPFEKRRDAACVFWDNVVYILGGSQLFPIKRMDCYNVVKDSWYSKLGPPTPRDSLAACAAEGKIYTSGGSEVGNSALYLFECYDTRTESWHTKPSMLTQRCSHGMVEANGLIYVCGGSLGNNVSGRVLNSCEVYDPATETWTELCPMIEARKNHGLVFVKDKIFAVGGQNGLGGLDNVEYYDIKLNEWKMVSPMPWKGVTVKCAAVGSIVYVLAGFQGVGRLGHILEYNTETDKWVANSKVRAFPVTSCLICVVDTCGANEETLET------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PBW9-1", "uniprot_id": "A0A8M1PBW9_DANRE", "id": "A0A8M1PBW9-1", "name": "", "aln": "MASTTCEKALGPKKKSEKKIASKEEYRLLSNIMGVMNNLRKQGILCDVILVVEGKHILAHRVVLSAASHFFSLMFTSSMMEASNHEVELGGAEPEIIELLVEFIYTARISVNSNNVQSLLNAANQYQIDPVKKMCVDFLKEQVDATNCLGISALAECLNCPELKVAADDFIHQHFTNVYKMDEFLQLDVKQVTHLLQQDTLTVRAEDQIYDAAVRWLKYDVLNRQHYIVDILGKVRFPLVSKNFLSKTVQAEPLIQDNPECLKMVICGMRYHLLSPEDREELGESSRPRRKKHDYRIALFGGSQPQSCRYFNPKDYSWSDIRCPFEKRRDAASVFWDNVVYILGGSQLFPIKRMDCYNVVKDSWYSKLGPPNPRDSLAACASKGKIYTSGGSEVGSSALNLFECYDTRTEAWQTKPNMLMPRCSHGSVEANGLIYVCGGSLGNNVSGRVLNDCEVYDPNTEEWRGLCGMREARKNHGLVVVNSRIYAVGGQNTLGGLDSVEYYEIGSNEWKMASPMPWRGVTVKCAAVGSVIYVLAGFQGVGRLGHIMEYYTDTDKWVVSSKVRAFPVTSCLICLVDTCGANEEDMSFTPSSSSSSSSASLADGRM", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:: **: ***:***:*::** :**:.:******:*** ****** *: ::* ******:******.****:.*:*:...**** .***:*** **** ****************:*******:****************:******.*****:***** :**********:*** *********:*****.***********:*********** *** ::****.******:**************************.*************** .:********************************:*************.**************************************.*********::************.*** **********:*:***.** ***** ***********************..****** ** * ** * *.*******.*:.:*:****** *****.****:* *****.*****:***********::***************:** *:****:..**************:********* :. ", "identical_positions": 477, "similar_positions": 74, "identity": "78.71%" }, { "cls_id": "homologset.agr.MGI:1196455", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A4L2-1", "uniprot_id": "D4A4L2_RAT", "id": "D4A4L2-1", "name": "", "aln": "-----------MEAVAAAAVAERKPDDDCVEARCVHWGELSQTSIPPGP-------QEK--------ETAESTPDVTSGDSSQAESP---AVSAMLHAIAASHLPVCSQQQGEPDLTEPEKVAILGQLYHKKPLVFLERFRTGLREEHLACFGHLRGDH--RADFYCAEVARQGTARPRTLRTRLR---NRRYAALRELIQGGEYFSDEQMRFRAPLLYEQYIGQYLTQEELSARTPAPQAPRSGSPGTPAYPLSDLLFQSYQERELQQKLLQQQEEEE-----------ACFEEEE---DSDEEDQRSDKDLEAWVPD------------SEERLILREEFTSRMHQRFLDGKDGGFDYSTVDDNPDFDNLDIVARDEEDRYFDEEEPEDVSSPELDGD---------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DBT3-1", "uniprot_id": "CCD97_MOUSE", "id": "Q9DBT3-1", "name": "Coiled-coil domain-containing protein 97", "aln": "-----------MEAVAAAEVTERKPDNDGVEPRVVHWGELSQTPIPSGP-------QEK--------ETAERTPDIPNSGSSQAESP---AVSAMLHAIAASHLPVCSQQQGEPDLTEPEKVAILGQLYHKKPLVFLERFRTGLREEHLACFGHLRGDH--RADFYCAEVARQGTARPRTLRTRLR---NRRYAALRELIQGGEYFSDEQMRFRAPLLYEQYIGQYLTQEELNARTAAPQAPRSGSPGTPAYPLSDLLFQSYQERELQQKLLQQQEEEE-----------ACFEEEE---DSDEEDQRSDKDSEAWVPD------------SEERLILREEFTSRMHQRFLDGKDGGFDYSTVDDNPDFDNLDIVARDEEDRYFDEEEPEDVSSAELGGD---------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96F63-1", "uniprot_id": "CCD97_HUMAN", "id": "Q96F63-1", "name": "Coiled-coil domain-containing protein 97", "aln": "-----------MEAVATATAAK-EPDKGCIEPGPGHWGELSRTPVPSKP-------QDKV-------EAAEATPVALDSDTSGAENA---AVSAMLHAVAASRLPVCSQQQGEPDLTEHEKVAILAQLYHEKPLVFLERFRTGLREEHLACFGHVRGDH--RADFYCAEVARQGTARPRTLRTRLR---NRRYAALRELIQGGEYFSDEQMRFRAPLLYEQYIGQYLTQEELSARTPTHQPPKPGSPGRPACPLSNLLLQSYEERELQQRLLQQQEEEE-----------ACLEEEEEEEDSDEEDQRSGKDSEAWVPD------------SEERLILREEFTSRMHQRFLDGKDGDFDYSTVDDNPDFDNLDIVARDEEERYFDEEEPEDAPSPELDGD---------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FBN4-1", "uniprot_id": "E7FBN4_DANRE", "id": "E7FBN4-1", "name": "", "aln": "MWGEIEPRVNGQESMKSRGTDQRRTHSPDPQQKTVLWGEIESTSKPDPPTWSQPASQDSLPALPHPPETNAREVNNTPSCSSDVQDEPPISLSAMIETIAASGSPVKSQQLGDPDLTLEEKREVLMDQYRSRPLVFLERYQAHLKPEHIDAFSHLSSDC--RVQYYCKEIQRRASGSAD--RRRVR---NHRYAALRALQKDGQYFSEEQMRVRDPLLYEQYIGQYLSEEEILQRS--EEVMRSGTGG-----LADLLIDSYQEKLIQSRLEQEQEKEQ-----------CALEESE---DEECEEVR----QAEYEPN------------AEEKAMLREEFLSQMHQRFLDGKD-DFNYSEVDENPDYDNLDIVSRDAEERYFDEDEEEEEEEEEEEEEQEEMTH---------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VLP6-1", "uniprot_id": "Q9VLP6_DROME", "id": "Q9VLP6-1", "name": "CCD97-like C-terminal domain-containing protein", "aln": "-----------------------MTTGSDADGDGDHQGNNDIVPNPEHP------------------------PEIIDIFKSLAENN---------------QIVFKSQQIDDPEIPVEEKQQIARDAFDKNRENFLIRFGGFLNVRQLGSFQELAVKEPIKADENLEEMCLLLEDFRRKLNTRAVSIKNRRYHAMQQLLDKGEYFSEHEMMQRAPDLYQELVGQYLTEAEKKARDS-YDVRNTSFSGILMHTLEKKQRDELLEETQQEGKQSVQVTSESNPQADCDVPVACRKQWGGFEDDEPVACSTSRNAEVRAPMNTTMISTPEFYNPGERELLRNEFLSMMKERFLSGEDKDFDYKAVDDNTLLDDLKQIEQDEEDAYFEDSEDEEELEEHAADENAISSEDDLDIYMRHLSNHHSLQNSHG", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : *: . .. * * .* .:. . *** .:*::. ** : : : .. ** *: *. .:: .* .: . :.: *: . * *:** *:: * . *:***:.:* * * **:: :****:: * * : ... * * . :. *. *. . * .: .. :: *.: * . *: :**:** * *::***.*:* .*:*. **:*. *:*. : :* *: **::.* *: . . : ", "identical_positions": 69, "similar_positions": 91, "identity": "16.16%" }, { "cls_id": "homologset.agr.MGI:1196457", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q03344-1", "uniprot_id": "ATIF1_RAT", "id": "Q03344-1", "name": "ATPase inhibitor, mitochondrial", "aln": "--MAGSALAVRARLGVWGMRVLQTR-GFGSDSSESMDSGAGSIREAGGAFGKREKAEEDRYFREKTREQLAALKKHHEDEIDHHSKEIERLQKQIERHKKKIKYLKNSEH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35143-1", "uniprot_id": "ATIF1_MOUSE", "id": "O35143-1", "name": "ATPase inhibitor, mitochondrial", "aln": "--MAGSALAVRARFGVWGMKVLQTR-GFVSDSSDSMDTGAGSIREAGGAFGKREKAEEDRYFREKTKEQLAALRKHHEDEIDHHSKEIERLQKQIERHKKKIQQLKNN-H", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UII2-1", "uniprot_id": "ATIF1_HUMAN", "id": "Q9UII2-1", "name": "ATPase inhibitor, mitochondrial", "aln": "--MAVTALAARTWLGVWGVRTMQAR-GFGSDQSENVDRGAGSIREAGGAFGKREQAEEERYFRAQSREQLAALKKHHEEEIVHHKKEIERLQKEIERHKQKIKMLKHDD-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A3KNL5-1", "uniprot_id": "ATF1A_DANRE", "id": "A3KNL5-1", "name": "ATPase inhibitor A, mitochondrial", "aln": "--MARLLLR--RGFFSSHIRMSSDQLGELGTGAGKGGGGGGSVRAAGGSFGRREAAEEERYFRQKEREQLAALKNHHEEEIDHHKKEIERLQREIDRHKGKIRKLKHDD-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q1LYB6-1", "uniprot_id": "ATF1B_DANRE", "id": "Q1LYB6-1", "name": "ATPase inhibitor B, mitochondrial", "aln": "--MARFLNSNIRKFLTTQIRMSSDQLGELGKGAGKGGGGGGAVRQAGGAFGKKQAAEEEMYFKRKEQEQLSALRRHHQEEIDHHKKEIERLQHEITRHESKIKKLKHDD-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q0E8X8-1", "uniprot_id": "Q0E8X8_DROME", "id": "Q0E8X8-1", "name": "ATP synthase F1 subunit epsilon", "aln": "MFVVRRSASRLYPAGVQLAKMSGSQVGDLGSGAGKGGGGGGSIREAGGAFGKLEAAREEEYFYKKQREQLDRLKNDQIHQAEFHHQQIKEHEEAIQRHKEFLENLHK---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "E1JGT3-1", "uniprot_id": "E1JGT3_DROME", "id": "E1JGT3-1", "name": "ATP synthase F1 subunit epsilon", "aln": "MFTLRRFSQRWYPKQIQHLKMS--QIGELGSGAGNGGGGGGSIREAGGSFGKMEAAREEEFFYKQQKEQLKNLKT-------------KTEPKAPEAPKK----------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : * . : . . *.*::* ***:**: : *.*: :* : :*** *: : . : ", "identical_positions": 16, "similar_positions": 21, "identity": "14.55%" }, { "cls_id": "homologset.agr.MGI:1196458", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P27615-1", "uniprot_id": "SCRB2_RAT", "id": "P27615-1", "name": "Lysosome membrane protein 2", "aln": "---MARCCFYTAGTLSLLLLVTSVTLLVARVFQKAVDQTIEKNMVLQNGTKVFDSWEKPPLPVYIQFYFFNVTNPEEILQGEIPL-LEEVGPYTYRELRNKANVQFGENGTTISAVTNKAYIFERNQSVGDPTVDLIRTINIPLLTVVEMAQQP-----------------------FLREIIEAMLKAYQ------------------------------QTLFVTHTVHELLWG-----------YKDEVLSLVH-------IFRPDVSPNFGLFYERNGTNDGEYVFLTGEDNYLNFTKIVEWNGKTSLDWWT-------TDTCNMINGTDGDSFHPLISKDETLYIFPSDFCRSVYITFSSFENVEGLPAFRYKVPAEILAN---SSENAGFCIP--------EGNCMDAGVLNVSICKNGAPIIMSFPHFYQADEKFVSAIKGMRPNKEEHESFVDINPLTGIILRGAKRFQINTYVKKLDDFVETGNIRTMVFPVMYLNESVLIDKETASQLKSVINTTLIVTNIPYIIMALGVFFGLIFTWLACRGQGSTDEGT------------------------------ADER---------APLIRT------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35114-1", "uniprot_id": "SCRB2_MOUSE", "id": "O35114-1", "name": "Lysosome membrane protein 2", "aln": "---MGRCCFYTAGTLSLLLLVTSVTLLVARVFQKAVDQTIEKNMVLQNGTKVFNSWEKPPLPVYIQFYFFNVTNPEEILQGEIPL-LEEVGPYTYRELRNKANIQFGENGTTISAVTNKAYVFERNQSVGDPNVDLIRTINIPLLTVVDLAQLT-----------------------LLRELIEAMLKAYQ------------------------------QKLFVIHTVHELLWG-----------YKDEILSLVH-------IFKPDVSPNFGLFYERNGTNDGEYVFLTGEDNYLNFSKIVEWNGKTSLDWWT-------TDTCNMINGTDGDSFHPLISKDEVLYLFPSDLCRSVHITFSSFENVEGLPAFRYKVPAEILAN---TSENAGFCIP--------EGNCMDSGVLNISICKNGAPIIMSFPHFYQADEKFVSAIKGMHPNKEEHESFVDINPLTGIILRGAKRFQINTYVRKLDDFVETGDIRTMVFPVMYLNESVLIDKETANQLKSVINTTLVVTNIPYIIMALGVFFGLVFTWLACRGQGSMDEGT------------------------------ADER---------APLIRT------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14108-1", "uniprot_id": "SCRB2_HUMAN", "id": "Q14108-1", "name": "Lysosome membrane protein 2", "aln": "---MGRCCFYTAGTLSLLLLVTSVTLLVARVFQKAVDQSIEKKIVLRNGTEAFDSWEKPPLPVYTQFYFFNVTNPEEILRGETPR-VEEVGPYTYRELRNKANIQFGDNGTTISAVSNKAYVFERDQSVGDPKIDLIRTLNIPVLTVIEWSQVH-----------------------FLREIIEAMLKAYQ------------------------------QKLFVTHTVDELLWG-----------YKDEILSLIH-------VFRPDISPYFGLFYEKNGTNDGDYVFLTGEDSYLNFTKIVEWNGKTSLDWWI-------TDKCNMINGTDGDSFHPLITKDEVLYVFPSDFCRSVYITFSDYESVQGLPAFRYKVPAEILAN---TSDNAGFCIP--------EGNCLGSGVLNVSICKNGAPIIMSFPHFYQADERFVSAIEGMHPNQEDHETFVDINPLTGIILKAAKRFQINIYVKKLDDFVETGDIRTMVFPVMYLNESVHIDKETASRLKSMINTTLIITNIPYIIMALGVFFGLVFTWLACKGQGSMDEGT------------------------------ADER---------APLIRT------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13A953-1", "uniprot_id": "A0AB13A953_DANRE", "id": "A0AB13A953-1", "name": "", "aln": "-MRLRLCCVSTAGALCVLLLICGIALELTRVLQKLVNNTVKQQIVLENGTEAFSVWQNPPPPVYMQFYFFNLTNPAEVMSGDKPS-VVQIGPYTYREYRPMEEVKFMDNGTRVAAINPKTYVFEPNMSRGS-QDDLVRTVNIPAVTVMEKYKDS-----------------------ILARLISDLMKAKG------------------------------VGVFETFRVGDLLWG-----------YEDPLLKELH-------MLVPDD--HFGLFYKKNGTEYDSYVLLTGKPDYQDFASIDEWNGQRSLNWWS-------SEECNMINGTDGASFHPIITKADRLYIFSSDLCRSLYVQYECDVSVQGVPGFRFVPPADVFSSPDINPDNAGFCVP--------PGHCLGSGLLNASVCKQGAPIIMSSPHFYQADQKFVDDIWGMKPIKEEHQTFADINPLTGIVLQGAKRVQVNVYLQQHSSFSQTGKIQTLVFPVMYINESAFIDEESAKKLHAVVLNANVVINIPFIVISVGILLGIIFIVLMCRQQ--MPPST------------------------------LAER---------EPLLSS------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A2R8Q7M1-1", "uniprot_id": "A0A2R8Q7M1_DANRE", "id": "A0A2R8Q7M1-1", "name": "", "aln": "-MRKSSCCMYSCGAAGALLLLAGIALFASGLFQTLIHNKLKKEITLTEGSKVFATWKNPPPPVYMEFFFFNVTNPEAFLKGEAKARLSEMGPYTYREYRPKHNVSFVDNGTKVAAYTPKVFVFVPEKSVGDPSVDMVTTVNIPAVAVMNRIKGAG---------------------FLVSSAMSLYMKSIG------------------------------AEMFMTHTVDELLWG-----------FKDPLLTKLR-------SIKPETDEFFGLMLHKNGSDDGEFVYHTGEHNYLDYGRIFTWKGEKLMSFWK-------TNQSNMINGTDGSAFHPFLTKEERLDVFTADLCRSIHMRFEKEVEVKGIPAYRFTPPRAVLASGTNNPENEGFCLT--------PKKCLDDGVLDVSVCRQGAPVVVSFPHFHLGDEKYVQAVEGLSPVHEQHQTFLDLNPTMGVPVRAMKRAQINIHLERVTGFPMTRNLESTIFPIIFLNESVVIDNASAERIQKLLLVVTLVSHFPLILVALGVILLIVAVILAVRYYQNKTEVKRFDFAEAFHCTAPSAKKDTSYAPVSAKVDDQDEKNGTYIGM--TPVDKS------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E1JI63-1", "uniprot_id": "SNMP2_DROME", "id": "E1JI63-1", "name": "Sensory neuron membrane protein 2", "aln": "--MIHWSLIVSALGVCVAVLGG---YCGWILFPNMVHKKVEQSVVIQDGSEQFKRFVNLPQPLNFKVYIFNVTNSDRIQQGAIPI-VEEIGPYVYKQFRQKKVKHFSRDGSKISYVQNVHFDFDAVASAPYTQDDRIVALNMHMNAFLQVFEREITDIFQGFANRLNSRLNQTPGVRVLKRLMERIRGKRKSVLQISENDPGLALLLVHLNANLKAVFNDPRSMFVSTSVREYLFDGV-RFCINPQGIAKAICNQIKESGSKTIREKSDGSLAFSFFGHKNGSGHEVYEVHTGKGDPMRVLEIQKLDDSHNLQVWLNASSEGETSVCNQINGTDASAYPPFRQRGDSMYIFSADICRSVQLFYQTDIQYQGIPGYRYSIGENFINDIGPEHDNECFCVDKLANVIKRKNGCLYAGALDLTTCLD-APVILTLPHMLGASNEYRKMIRGLKPDAKKHQTFVDVQSLTGTPLQGGKRVQFNMFLKSINRIGITENLPTVLMPAIWVEEGIQLNGEMVAFFKKKLINTLKTLNIVHWATLCGGIGVAVACLIYYIYQRGRVVEP--------------------------------------------PVK--------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VDD3-1", "uniprot_id": "SNMP1_DROME", "id": "Q9VDD3-1", "name": "Sensory neuron membrane protein 1", "aln": "MQVPRVKLLMGSGAMFVFAIIYG-----WVIFPKILKFMISKQVTLKPGSDVRELWSNTPFPLHFYIYVFNVTNPDEVSEGAKPR-LQEVGPFVFDEWKDKYDLEDDVVEDTVSFTMRNTFIFNPKESLPLTGEEEIILPHPIMLPGGISVQRE------------------------KAAMMELVSKGLSIVFP-------------------------DAKAFLKAKFMDLFFRGINVDCSSEEFSAKALCTVFYTGEIKQAKQVNQTHFLFSFMGQANHSDSGRFTVCRGVKNNKKLGKVVKFADEPEQDIWP-------DGECNTFVGTDSTVFAPGLKKEDGLWAFTPDLCRSLGAYYQHKSSYHGMPSMRYTLDLGDIRA---DEKLHCFCEDP-----EDLDTCPPKGTMNLAACVG-GPLMASMPHFYLGDPKLVADVDGLNPNEKDHAVYIDFELMSGTPFQAAKRLQFNLDMEPVEGIEPMKNLPKLILPMFWVEEGVQLNKTYTNLVKYTLFLGLKINSVLRWSLITFSLVGLMFSAYLFYHKSDSLDINSILKDNNKVDDVASTKEPLPSANPKQSSTVHPVQLPNTLIPGTNPATNPATHHKMEHRERY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : :: . :. :.:.:.: *:. : : * *: .:.**:**. . * : ::**:.: : : :: : * * : : : . : :. * . : :: . : . . : *.:: . * : : * . : .. . * .* : ***. : * : : : *..*:***: :. . .*:*. *: : . ** * * :: : * .*:: : **: .. . : *: * :.* : *.: * .:. ** *.* :. : .: . ::* ::::*. :: . .: : . : : * ", "identical_positions": 50, "similar_positions": 128, "identity": "8.04%" }, { "cls_id": "homologset.agr.MGI:1196463", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AXU9-1", "uniprot_id": "A0A8I6AXU9_RAT", "id": "A0A8I6AXU9-1", "name": "Fibronectin type-III domain-containing protein 3A", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSVCFCHSWRAFRCIDALLMMAEHPPLLDTAQILSSDISLLSAPIVSADGTQQVILVQVNPGEAFTIRREDGQFQCITG----------------PAQVPMMSPNGSVPPIYVPPGYAPQVIEDNGVRRVVVVPQ-SPEFHPGG-----------------HTVIHRSPHPPLPGFIPVPTMMPPPP---------------------------------------------------RHMYSPVTGAGDMATQYMPQYQSSQVYADVDAHSTHGRS--NFRDERSTKTYERLQKKLKDRQGTQKDKMSSPPPS----------------------------------------------PQKCPSPISEHNGLIKGQNTSGVNTGSARNRSGRGRGCTQVDQEIEEKDEETKAFEAFLSNIVRPVASDIQARTVLLTWSPPSSFVNGEVTETTVPEFFNYEILVSSTGKEGKYRSVYVGEETSVTLNDLKPATDYHAKVQAESNSIKGIPSEAESFTTLSCEPDTPNAPRIANRTKNSLTLQWKAPSDNGSKIQSFILEWDEGKGSGE---FCQCYMGSQKQFKITKLSPAMGCKFRLSAKNDYGVSDFSEEVLYYTSGCAPSVPASPVLTKAGVTWLSLQWTKPSGTPSDEGISYILEMEEETSGYGFKPKYDGEDLAYTVKNLRRSTKYKFKVIAYNSEGKSSPSEVVEFSTCPDKPGVPAKPSVKGKVHSHGFKITWDPPRDNGGAPINKYVVEMAEGSNGSKWDMIYSGATREHLCDRLTPGCYYRLRVYCISDGGQSAVSESLLVQTPAVPPGPCLPPRLQGRPKAKEIQLRWGPPQVDGGSPISCYAVEMTPADKDEP-RDVYQGSEVECTVSSLLPGKTYSFRLRAANRIGFGPFSEKYDITTAPGPPDQCRPPQVTCRSATCAQVNWEIPLS-NGTDITEYRLEWGGVEG---------------SMQICYCGPGLSCELKGLSPATTYYCRVQALSVVGAGPFSEVVACVTPPSVPAIVTCLQEIRDDDIEYPHYSPSTCLAISWEEPYDHGSEILAYSIDLGDKQPLTVGKVTSYVINSLQPDTTYRIRIQALNSLGAGPFSHTIKLKTKPLPPDPPRLECVAFNHQNLKLKWGEG--------TPKTLATDAVQYHLQMEDK-NGRFVSLYRGPCHTYKVQRLSESTSYKFCIQACN-EAGEGPLSQEYVFTTPKSVPAALKAPKIEKIN-----------DHICEITWEYLQPMKGDPVIYNLQVMVG------------------------------KDSEFKQIYRGPDTSFRYSSLQLNCEYRFRVCAIRQCQD------------------------PAGHQDLVGPYSTTVFFISQRTEPLASSNRDTVDSARTR----------------------------------------------------------------------------------------------------------------------------------RTLSDEQCAAVILVLFAFFSILIAFIIQYFVIK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BX90-1", "uniprot_id": "FND3A_MOUSE", "id": "Q8BX90-1", "name": "Fibronectin type-III domain-containing protein 3A", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAEHPPLLDTAQILSSDISLLSAPIVSADGTQQVILVQVNPGEAFTIRREDGQFQCITG----------------PAQVPMMSPNGSVPPIYVPPGYAPQVIEDNGVRRVVVVPQ-SPEFHPGG-----------------HTVIHRSPHPPLPGFIPVPTMMPPPP---------------------------------------------------RHMYSPVTGAGDMATQYMPQYQSSQVYADVDAHSTHGRS--NFRDERSSKTYERLQKKLKDRQGTQKDKMSSPPPS----------------------------------------------PQKCPSPISEHNGLIKGQNASGGNTGSARNRSGRGRSCTQVDPEMEEKDEETKAFEAFLSNIVKPVASDIQARTVLLTWSPPSSFINGEVNETAVPELFNYEVLVSSTGKEGKYRSVYIGEETSVTLNDLKPATDYHAKVQAESNSIKGIPSEAESFTTLSCEPDPPNAPRIANRTKNSLTLQWKAPSDNGSKIQSFILEWDEGKGNGE---FCQCYMGSQKQFKITKLSPAMGCKFRLSAKNDYGVSDFSEEVLYYTSGCAPSVPASPVLTKAGVTWLSLQWTKPSGTPSDEGISYILEMEEETSGYGFKPKYDGEDLAYTVKNLRRSTKYKFKVIAYNSEGKSNPSEVVEFSTCPDKPGVPVKPSVKGKIHSHGFKITWDPPKDNGGAPINKYVVEMAEGSNGNKWDMIYSGTTREHLCDRLTPGCYYRLRVYCISDGGQSAVSESLLVQTPAVPPGPCLPPRLQGRPKAKEIQLRWGPPQVDGGSPISCYAVEMTPADKDEP-RDVYQGSEVECTVGSLLPGKTYSFRLRAANRIGFGPFSEKYDITTAPGPPDQCRPPQVTCRSATCAQVNWEIPLS-NGTDVTEYRLEWGGVEG---------------SMQMCYCGPGLSCELKGLSPATTYYCRVQAMSVVGAGPFSEVVACVTPPSVPAIVTCLQEISDDDIEYPHYSPSTCLAISWKEPYDHGSEILAYSIDLGDKQPLTVGKMTSYIIDSLQPDTTYRIRIQALNSLGAGPFSHTIKLKTKPLPPDPPRLECVAFNHQNLKLKWGEG--------TPKTLSTDAVQYHLQMEDR-NGRFVSLYRGPCHTYKVQRLSESTSYKFCIQACN-EAGEGPLSQEYVFTTPKSLPAALKAPKIEKIN-----------DHICEITWEYLQPMKGDPVIYNLQVMVG------------------------------KDSEFKQIYKGPDTSFRYSSLQLNCEYRFRVCAIRQCQD------------------------PTGHQDLVGPYSTTVFFISQRTEPPASSNKDSVDSARTR----------------------------------------------------------------------------------------------------------------------------------RTLSDEQCAAVILVVFAFFSILIAFIIQYFVIK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y2H6-1", "uniprot_id": "FND3A_HUMAN", "id": "Q9Y2H6-1", "name": "Fibronectin type-III domain-containing protein 3A", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAEHPPLLDTTQILSSDISLLSAPIVSADGTQQVILVQVNPGEAFTIRREDGQFQCITG----------------PAQVPMMSPNGSVPPIYVPPGYAPQVIEDNGVRRVVVVPQ-APEFHPGS-----------------HTVLHRSPHPPLPGFIPVPTMMPPPP---------------------------------------------------RHMYSPVTGAGDMTTQYMPQYQSSQVYGDVDAHSTHGRS--NFRDERSSKTYERLQKKLKDRQGTQKDKMSSPPSS----------------------------------------------PQKCPSPINEHNGLIKGQIAGGINTGSAKIKSGKGKGGTQVDTEIEEKDEETKAFEALLSNIVKPVASDIQARTVVLTWSPPSSLINGETDESSVPELYGYEVLISSTGKDGKYKSVYVGEETNITLNDLKPAMDYHAKVQAEYNSIKGTPSEAEIFTTLSCEPDIPNPPRIANRTKNSLTLQWKAPSDNGSKIQNFVLEWDEGKGNGE---FCQCYMGSQKQFKITKLSPAMGCKFRLSARNDYGTSGFSEEVLYYTSGCAPSMPASPVLTKAGITWLSLQWSKPSGTPSDEGISYILEMEEETSGYGFKPKYDGEDLAYTVKNLRRSTKYKFKVIAYNSEGKSNPSEVVEFTTCPDKPGIPVKPSVKGKIHSHSFKITWDPPKDNGGATINKYVVEMAEGSNGNKWEMIYSGATREHLCDRLNPGCFYRLRVYCISDGGQSAVSESLLVQTPAVPPGPCLPPRLQGRPKAKEIQLRWGPPLVDGGSPISCYSVEMSPIEKDEP-REVYQGSEVECTVSSLLPGKTYSFRLRAANKMGFGPFSEKCDITTAPGPPDQCKPPQVTCRSATCAQVNWEVPLS-NGTDVTEYRLEWGGVEG---------------SMQICYCGPGLSYEIKGLSPATTYYCRVQALSVVGAGPFSEVVACVTPPSVPGIVTCLQEISDDEIENPHYSPSTCLAISWEKPCDHGSEILAYSIDFGDKQSLTVGKVTSYIINNLQPDTTYRIRIQALNSLGAGPFSHMIKLKTKPLPPDPPRLECVAFSHQNLKLKWGEG--------TPKTLSTDSIQYHLQMEDK-NGRFVSLYRGPCHTYKVQRLNESTSYKFCIQACN-EAGEGPLSQEYIFTTPKSVPAALKAPKIEKVN-----------DHICEITWECLQPMKGDPVIYSLQVMLG------------------------------KDSEFKQIYKGPDSSFRYSSLQLNCEYRFRVCAIRQCQD------------------------SLGHQDLVGPYSTTVLFISQRTEPPASTNRDTVESTRTR----------------------------------------------------------------------------------------------------------------------------------RALSDEQCAAVILVLFAFFSILIAFIIQYFVIK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B7YZW3-1", "uniprot_id": "B7YZW3_DROME", "id": "B7YZW3-1", "name": "", "aln": "MAAAVLEINENQLELVCDECDYYGATDTIFIDNSTQTDGYDDDESELKPLKPRLSQIVEEEAEMEGTVKEEMDTQVETNGIQSDSNGVSDVKTAINGNESIVAEEISEEEPPVEASVPHVVQELVDSDDEVEIDDVTRLAGLTLGMGYARIIDYDNLRIIEHVIESDDEDDNNVAAAGTAATSAELQQACHDLVTFIGESYQVIERSGHSREPTATLSVVDNNNNNRSSEVSTNGRGAITDRSKSTRKVHNGLQVNQNASTSATATSSSNSKSNSSNNTAATSNSSALIKAYKSNLTPLAPPFQPAALKAKQLQQSSLPSGNMSSVTTTTTTALGYTAYEQTTVYYQQQVQQQQQQHPQQQQQLSPKQQQQQQQQPQQQQPICAQHGGLPHIHGAQLLPVQLIALPPNGVTAAAATAAVAAAAGATVAAAGTPAAAAAGGAAATSLTGAAWPLVEAPIYIDINGEYRSYCPAHGPPAVAVPNGAIGHHPHIHAHPPHTHSHAHPTHSHHAQQQQQQQQQQQQQLHHHHQQHGQHQQHLTPSPVTNVNGNIAQAAAAAASAPRLLLQLDAATVQQQQQQQHQQQQQHQQQQQQQIVAAGKRSKVYRGPAVQMVSQNRPPPPMPVPVQVPQYVNENGTLTHVMLSPQQYQQLHPGQGHLHPAPFISANGTSHFYTPVAGYPGPGPAGNGPPHYHLPPPPPPQQQQQQPPQQPQQQAPQGPPPPQQQQQQQQQVAPPAVQGAPSTGSVGAAQGAPATATATHTHAHSHSHSHAHSHTHPQPHAHSPHSPSPPNYRDERSQRQHNKLLRKLEKQRESNPPHSPSPRRANELNGHNNNNIPPGVPLPGHLNNHHHAVNHQGRRLPQQHQGQAHQVAQQQQSQARNGNPQHPQRAGSSVGGASSVGTSEDGEDNSSLAGDDEEEYHRENSIIEQISAIEKPEVIDVTSRAAKIIWESPAIANTVTVDMR----QLRYQVLLCDSGKQCKYKSLYQGEAYECIVQDLQPGQDYLVRLQVHYQKLTGTVSDPTEFRTPPCEPDQPPPPKLVSRTKNSINLRWAAPAANGASIQHYLLEYDEGRMPGQPQKFVELAKIKAKHYVIGKLQPTTVYSFRLAAVNEAGQSPYSPVASYSTSGNPPPVPKPPQLLASSSSSLKLGWERRAQDGD-----FLLQLQDAETGHGFLNTYKGTELQTECLQLRRASSYQFRLRSENEAGFSPWSPEVSYRTLAERPGRPGKPHAKGKIHGTQFKARWDAPSDSGGAEILCYHLELS--AAGPAFERIYSGAETEAMCERLQPGTTYALRACCEGPAGQSPYSDIGHVTTEAVPPSAPPPPHCSDPPSPYAALLKLRPPEYNGGAPILEFEAQMRRLEQVQPPQLVYRGKQTYFVAQDLTPGGMYETQVRAINRIGAGSWSQWMRFTAAAAAPGVPEELRVLVKSATHLGVSWQPPLQENGAPVTSYTLKSASQERKEDDSEEEVKEPPSSEFHNCYQGPQTCAELRNLSPYTRYHFRIQASNSAGTGNSSDVISVCTPAAVPGAP----------QMQGYEFTAQEVTLNWTQPAAHGSPICSYNIEYGERTIATPDACTRYTVSGLMPETGYKFRVQAVNAIGAGAFSAYAKLTTQPAPPAPPRLECSGAGHNYIKLKWGENGNGKVVNSNPSGNGGDFTKYFVEMYVARAKQFQAVYSGTNCMCKVHKLQERSSYTFRIYAHTDRAGDGDYSEEFVFETSATLPANIKPPRVVQEGSVCLMELPGQLGMQLTLEWQHSKNSFNDRVEYELQYAVLGAAELEGESLSPKGRSSSSSGSSNGAPINLPNHDYRQLYRGPETKFTIDNLAAGTCYQFRVCPVRIAAGGELLYGQPSSPLRYQVPSELDPSSATCHHHLHGSTATPAMASSQRSSRKLSAGNGSTNGLHMRSVSASAISGASGVGADPVAIGRLQQELSGFNACADPQHHHHHHHHHHHQPCGGGVGGAGGISGATDSHHQHQHHMHHSHHMHHAHHPHTGMGGSSSNSSSSTAAAISSSLAQAGGLRRIVCKVTSLYSNRRRLSDQQKAVCIVVSFLVGTFLVAMLVNMLRG-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:* * .: : . : .: .*. .:*...: :: ::. . : ::.: * * . * *:* * . **: ** . * *:. : :*:: ** ::*** :* : * * .* * :**** : :..*.: : .: .: *:.: : .***.*. * *:***** : :::* :**:.:: :: : .** : .*: * : * : .. . .*: * *.. :.: : **: .. ::: :* * :* . *: :*:. : *..*: . . *::*:..:**: **:*:* ** . ::**:*. ** .::*.. :.:.* *:. * * .**** * .*::..*****:.*:* **: **:.** ::**:***: *: * : . *:: * **.*: .***:* *: * * :* . * *** .*.:* .* * :. : *.* * : : . ::*:::: :*:** .*.* :* :***::.*:*:: : *. * * * *.: * .::** * ** .***:*. ** **.* *.*** * * :*:: : * :: ****: * :*:** ** * **. * . .***. *: * * ****.. **: .. *.. *: ** :**:** : .:* :: :* : **:*.:. .. .* ** *. ::** *::* *.:*: :*:*...*. . :* :*** *.*: **. **: :*.* *: .. * .:: ** ** . *::.*** * *: *:** . .*:* *:*:: **.:**. : .: :::.* :* *** * :*.*: *:: * . * * :..* *:* *::*:**:*::***.** **.*:* ** ****** . .*: :******. .*. . * :*.::* :* ::* *. **::*.* :**.* * * . .**:* *:*::* *. ::** :*.*:: : . . : *: : .* * *.** : : :::*:*:**::.* ..* . *:****.:* . . . *:.* *. :*..: ***:. *:...:.:. : * * ***:* *. *:* * . ::*:*:::: : ", "identical_positions": 370, "similar_positions": 406, "identity": "17.74%" }, { "cls_id": "homologset.agr.MGI:1196464", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LLS8-1", "uniprot_id": "A0ABK0LLS8_RAT", "id": "A0ABK0LLS8-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVLSSIRLLGILFGILFEGGFLSMLLIWSILQMMTISAS-----------------------------CPQCNENAICFNSTHCICKEGFWTG--SENRRIIEPHVKCQDIDECRLEETLCKDVSYCRNKIGT------------------------------------------------------YICSCVVKYPIINWVAAIFDIDHP----------------DCYVNKSNEIGSKAACTSGVLYDCNSKEDVAKGATVYLQN----TERHILNENSDTPIKSST--RDIVYETNKCKKTTILEAGNNTMKIN-----CTSVLKENKNRDETTVAFIAYKSLGNLLNGSFFRNKEGFQE--------VKLNSHIVSGAIRSEIKPVLSEPVILTLQN---------------TQPIDSRAEHLCVYWEGSEEGGSWSTKGCSHVYTNKSYTICKCFHLSSFAVLVGLSNEENA-----VLSALSVITYVGLSLSLLCLFLAAITFLLCR--PIQNTSTTLHLQLSICLFLADLLFLIGINRTKPKVLCSIIAGMLHYLYLASFMWMFLEGLHLFLTVRNLKVANYSHSGRFKKRLMYPVGYGFPALIVAVSAIAGHKNYGTYNHCWLSLHRGFIWSFLGPVAAIILINLVFYFQVLWILRSKLS---SLNKEVSTLQDTKIMTFKAIVQLFVLGCSWGIGLFIF--FEVGKTVRLIFAYLFTIINVLQGVLIFLVHCLLNRQVRMEYKKWFHRLQRETESESTELSHSTTHTKMGSSLKTENFCQTGNLHD-SNPQNTRADVK-CLPAVPVS--------CLLACCHDP-EHDYPGLFL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91ZE5-1", "uniprot_id": "AGRE4_MOUSE", "id": "Q91ZE5-1", "name": "Adhesion G protein-coupled receptor E4", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLMGATRDMGSRC--LLHASVPGMLLIWSILQMMNISAS-----------------------------CPQCNENASCFNSTHCVCKEGFWTG--SENRRIIEPHEKCQDINECLLKELVCKDVSYCRNKIGT------------------------------------------------------YICSCVVKYPLFNWVAGIINIDHP----------------DCYVNKSKNTGSKT-HTLGVLSEFKSKEEVAKGATKLLRK----VEHHILNENSDIPKKDENPLLDIVYETKRCKTMTLLEAGNNTMKVD-----CTSGFKEHNSGGETAVAFIAYKSLGNLLNGSFFSNEEGFQE--------VTLNSHIVSGAIRSEVKPVLSEPVLLTLQN---------------IQPIDSRAEHLCVHWEGSEEGGSWSTKGCSHVYTNNSYTICKCFHLSSFAVLMALPHEEDG-----VLSALSVITYVGLSLSLLCLFLAAITFLLCR--PIQNTSTTLHLQLSICLFLADLLFLTGINRTKPKVLCSIIAGMLHYLYLASFMWMFLEGLHLFLTVSNLKVANYSNSGRFKKRFMYPVGYGLPAFIVAVSAIAGHKNYGTHNHCWLSLHRGFIWSFLGPAAAIILINLVFYFLIIWILRSKLS---SLNKEVSTLQDTKVMTFKAIVQLFVLGCSWGIGLFIF--IEVGKTVRLIVAYLFTIINVLQGVLIFMVHCLLNRQVRMEYKKWFHRLRKEVESESTEVSHSTTHTKMGLSLNLENFCPTGNLHDPSDSILPSTEVAGVYLSTPRS--------HMGAEDVNSGTHAYWSRTISD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86SQ3-1", "uniprot_id": "AGRE4_HUMAN", "id": "Q86SQ3-1", "name": "Putative adhesion G protein-coupled receptor E4P", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGSRF-----------------------LLVLLSGAS-----------------------------CPPCPKYASCHNSTHCTCEDGFRAR--SGRTYFHDSSEKCEDINECETGLAKCKYKAYCRNKVGG------------------------------------------------------YICSCLVKYTLFNFLAGIIDYDHP----------------DCYENNSQ-------------------------------------------------------------------------------------------------------------------------------------------------GTTQSNVDIWVSG-VKPGFGK---------------QLPGDKRTKHICVYWEGSE--GGWSTEGCSHVHSNGSYTKCKCFHLSSFAVLVALAPKED--------PVLTVITQVGLTISLLCLFLAILTFLLCR--PIQNTSTSLHLELSLCLFLAHLLFLTGINRTEPEVLCSIIAGLLHFLYLACFTWMLLEGLHLFLTVRNLKVANYTSTGRFKKRFMYPVGYGIPAVIIAVSAIVGPQNYGTFT-CWLKLDKGFIWSFMGPVAVIILINLVFYFQVLWILRSKLS---SLNKEVSTIQDTRVMTFKAISQLFILGCSWGLGFFMV--EEVGKTIGSIIAYSFTIINTLQGVLLFVVHCLLNRQVRLIILSVISLVPKSN-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1Z7G7-4", "uniprot_id": "LPHN_DROME", "id": "A1Z7G7-4", "name": "Latrophilin Cirl", "aln": "MLPTILSISYEHISLDLSKYQTAYACEGKKLTIECDPGDVINLIRANYGRFSITICNDHGNVEWSVNCMFPKSLSVLNSRCAHKQSCGVLAATSMFGDPCPGTHKYLEAHYQCISAAQTSTTTNRPSPPPWVLSNGPPIFGNGSGLIHPPGVGAGAPPPPRLPTLPGVVGISGNPGLFNVPPQHTAVTHSTPSSSTTAVGGGRLKGGATSTTTTKHPAGRHDGLPPPPQLHHHHNHHGEDTASPTKPSSKLPAGGNATSPSNTRILTGVGGSGTDDGTLLTTKSSPNRPPGTAASGSVVPGNGSVVRTINNINLNAAGMSGGDDESKLFCGPTHARNLYWNMTRVGDVNVQPCPGGAAGIAKWRCVLMKRIPDSGYDEYDDDISSTTPAPSGGDCLHNSSSCEPPVSMAHKVNQRLRNFEPTWHPATPDLTQCRSLWLNNLEMRVNQRDSSLISIANDMSEVTSSKTLYGGDMLVTTKIIQTVSEKMMHDKETFPDQRQREAMIMELLHCVVKTGSNLLDESQLSSWLDLNPEDQMRVATSLLTGLEYNAFLLADTIIRERSVVQKVKNILLSVRVLETKTIQSSVVFPDSDQWPLSSDRIELPRAALIDNSEGGLVRIVFAAFDRLESILKPSYDHFDLKSSRSYVRNTAILSNDSDVNAGEIQQRLRILNSKVISASLGKGRHIQLSQPITLTLKHLKTENVTNPTCVFWNYID--HAWSANGCSLESTNRTHSVCSCNHLTNFAILMDVVDEHQHSLFTMFDGNMRIFIYISIGICVVFIVIALLTLKLFNGVFVKSARTSIYTSIYLCLLAIELLFLLGIEQTETSIFCGFITIFLHCAILSGTAWFCYEAFHSYSTLTSDELLLEVDQT-PKVNCYYLLSYGLSLSVVAISLVIDPSTYTQNDYCVLMEANALFYATFVIPVLVFFVAAIGYTFLSWIIMCRKSRTGLKTKEHTRLASVRFDIRCSFVFLLLLSAVWCSAYFYLRGAKMDDDTADVYGYCFICFNTLLGLYIFVFHCIQNEKIRREYRKYVRQHAWLPKCLRCSKTSISSGIVTGNGPTAGTLCSVSTSKKPKLPLGVSEEAHDDPQQQQQTPVPITEDAIMGATSDCELNEAQQRRTLKSGLMTGTLQAPPQTLGGHVVLERGSTLRSTGHASPTSSAGSTHLIFAHKQQQQQQQQGPLGESYYHQPDYYSWKQPSTGTGGLKTPREYYNNAGAAASSPQQAHEVFYWTQKPNSGHNGKKKRGAGGVPASPSGSLHSRTAAASQVLFYPSYKKTKPGQPTGYPQYAEALDPPLATGNAAAYYQQQQQLRRQQLHQQQQQQQQQQLSSDEEQAEQHAHLLHLQRRAGSQQQLPAPPPHMAQYQQEFMQRQYRNKHSNCDLGMGDAYYNQGSVGGADGGPVYEEILSNRNSDVQHYEVGDFDVDEVYNNSVGTGVFNNMRAAVAAGGSRYGGGSLSGGSVSSRSQQQQLKKQQQQQSLAQQRSARRCTADDDDDEDEEEDEEATAAEQLHDSVCDEDEEEDESDLEDDAHGLPPQSDERMRRLMAMQDEDFKRRFQRQLRKHGAPLDYGALPPGAGPQPEHNGAVFGVSGGVGEGSLRGAFRQQQQQALNAKSPGGRLAVNELFGHGNSGPPLPPANQTPAQKRQQLQKLSPQSTTSSSSHTSHSNPNPHPHQLTHPHPHQHPPHHQQRHLSAMLDENNTVRCYLEPLAK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. : : . * * * . :* . : . .. . . .:* *: :*:. * . :*. ::: :: : *: .* :... * :..: * : : : :. :: **.*: : .**::*** :* ::: *.* **:.**:*: : :.: : :: :.: :.:: :.:* :*: * . ::.: *::: .: :**: .**** **::*:..::*.:*: :** *: *: *.:* : *: . :: * . * :.**:. ::*:* : . ..* * * ..:::: : . :::: : * : **: .: * .** : : ..:. :: *::*.. * . * . ::.. : .* * :*.* *: :*:.**: *.::* . . ", "identical_positions": 80, "similar_positions": 175, "identity": "4.67%" }, { "cls_id": "homologset.agr.MGI:1196466", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LYX9-1", "uniprot_id": "F1LYX9_RAT", "id": "F1LYX9-1", "name": "", "aln": "-------------------------MARSPSGRCTLLLLLQLLAVVCLDFGDGLHLEVFSTRGEDRLFTKRTHLVRQKRAWITAPVALREGEDLSKKNPIAKIHSDLAEERGIKITYKYTGKGITEPPFGIFVFDRNTGDLNITSILDREETPFFLLTGYALDSRGNNLEKPLELRIKVLDINDNEPVFTQEVFVGSIEELSAAHTLVMKITATDADDPQTLNSKISYRIVSQEPANTPVFYLNKDTGEIYTTSFALDREEHSSYSLTVEARDGNGQITDKPVQQAQVQIRILDVNDNIPVVEYGTYEGVVEENQVNVEVMRIKVTDADEVGSDNWLANFTFASGNEGGYFHIETDTQTNEGIVTLVKELDYEEMKKLDLSILVTNKAAFHKSVVS-------------------------------------------KYKATPIPITVKVKNVVEGIHFKSSTVTFRASEAMDRSSLSRSIGKFQVFDEDTGKAAD-VTYVKVQDTDNWVSVDSETSEIKLVKIPDFESRHVQNGTYTVKVVAISKGHPQKTVTGTILINVEDVNDNCPVLVDSVRSVCADAPYVNVTAEDLDGPRNSGPFTFSIIDQPPGTAQKWKITHQESTSVLLQPSERKL-GRSEIPFLISDSQGFSCLERQVLQLTVCECLEGGGCVAALYDN---YVGLGPAAIALMILALLLLLLVPLLLLMCHCGEG--AKGFAPIPGTIEMLHPWNNEGAPPEDKVVPSLLVTDHVENSGVRGGGGGGGGGVGGVKLKEGVS---SSASITKGQHELIEVDGRWEEHRSLLTSGLTHHVATAGSIAANDTTIRTTRATGASRDMSGARG-AVAMNEELLRSYFTEKAASYAGEDDFHLAKDCLLVYSQEDTDSLRGSVG-CCSFIEGELDDLFLDDLGPKFKTLAEVCLGRKIDMDVDIEQRQKPVRETSVNAAPGSHYTQVTASSESTYSSNSGFQAPKPLHGAHTEKVTQEVVTESSVSSRQSQKVVPP-PNPVASGNIIVTETSYAAGSAVPPSTVILAPRQPQSLIVTERVYAPASTLVDQHYAN--EENVLVTERVIQPNGGIPKPLEVTQHLNDAQYVMVRERESILAPSSGVQPTLAMPSVAAGGQNVTVTERVLTPASTLQSSYQIPSEASIKARKTVLSSVGGMGPLP---------------NLDLEESGPPNSTVTTSSTRVTKHSTVQHSYS--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O55111-1", "uniprot_id": "DSG2_MOUSE", "id": "O55111-1", "name": "Desmoglein-2", "aln": "-------------------------MARSPGDRCALLLLVQLLAVVCLDFGNGLHLEVFSPRNEGKPFPKHTHLVRQKRAWITAPVALREGEDLSRKNPIAKIHSDLAEEKGIKITYKYTGKGITEPPFGIFVFDRNTGELNITSILDREETPYFLLTGYALDSRGNNLEKPLELRIKVLDINDNEPVFTQEVFVGSIEELSAAHTLVMKITATDADDPETLNAKVSYRIVSQEPANSHMFYLNKDTGEIYTTSFTLDREEHSSYSLTVEARDGNGQITDKPVQQAQVQIRILDVNDNIPVVENKMYEGTVEENQVNVEVMRIKVTDADEVGSDNWLANFTFASGNEGGYFHIETDTQTNEGIVTLVKEVDYEEMKKLDLSIIVTNKAAFHKSILS-------------------------------------------KYKATPIPITVKVKNVVEGIHFKSSVVSFRASEAMDRSSLSRSIGNFQVFDEDTGQAAK-VTYVKVQDTDNWVSVDSVTSEIKLVKIPDFESRYVQNGTYTAKVVAISKEHPQKTITGTIVITVEDVNDNCPVLVDSVRSVCEDEPYVNVTAEDLDGAQNSAPFSFSIIDQPPGTAQKWKITHQESTSVLLQQSERKR-GRSEIPFLISDSQGFSCPERQVLQLTVCECLKGGGCVAAQYDN---YVGLGPAAIALMILALLLLLLVPLLLLICHCGGG--AKGFTPIPGTIEMLHPWNNEGAPPEDKVVPSLLVADHAESSAVRGG-------VGGAMLKEGMMKGSSSASVTKGQHELSEVDGRWEEHRSLLTAGATHHVRTAGTIAANEAVR--TRATGSSRDMSGARG-AVAVNEEFLRSYFTEKAASYNGEDDLHMAKDCLLVYSQEDTASLRGSVG-CCSFIEGELDDLFLDDLGLKFKTLAEVCLGRKIDLDVDIEQRQKPVREASVSAASGSHYEQAVTSSESAYSSNTGFPAPKPLHEVHTEKVTQEIVTESSVSSRQSQKVVPP-PDPVASGNIIVTETSYAKGSAVPPSTVLLAPRQPQSLIVTERVYAPTSTLVDQHYAN--EEKVLVTERVIQPNGGIPKPLEVTQHLKDAQYVMVRERESILAPSSGVQPTLAMPSVAAGGQNVTVTERILTPASTLQSSYQIPSETSITARNTVLSSVGSIGPLP---------------NLDLEESDRPNSTITTSSTRVTKHSTMQHSYS--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14126-1", "uniprot_id": "DSG2_HUMAN", "id": "Q14126-1", "name": "Desmoglein-2", "aln": "-------------------------MARSPGRAYALLLLL-----ICFNVGSGLHLQVLSTRNENKLLPKHPHLVRQKRAWITAPVALREGEDLSKKNPIAKIHSDLAEERGLKITYKYTGKGITEPPFGIFVFNKDTGELNVTSILDREETPFFLLTGYALDARGNNVEKPLELRIKVLDINDNEPVFTQDVFVGSVEELSAAHTLVMKINATDADEPNTLNSKISYRIVSLEPAYPPVFYLNKDTGEIYTTSVTLDREEHSSYTLTVEARDGNGEVTDKPVKQAQVQIRILDVNDNIPVVENKVLEGMVEENQVNVEVTRIKVFDADEIGSDNWLANFTFASGNEGGYFHIETDAQTNEGIVTLIKEVDYEEMKNLDFSVIVANKAAFHKSIRS-------------------------------------------KYKPTPIPIKVKVKNVKEGIHFKSSVISIYVSESMDRSSKGQIIGNFQAFDEDTGLPAH-ARYVKLEDRDNWISVDSVTSEIKLAKLPDFESRYVQNGTYTVKIVAISEDYPRKTITGTVLINVEDINDNCPTLIEPVQTICHDAEYVNVTAEDLDGHPNSGPFSFSVIDKPPGMAEKWKIARQESTSVLLQQSEKKL-GRSEIQFLISDNQGFSCPEKQVLTLTVCECLHGSGCREAQHDS---YVGLGPAAIALMILAFLLLLLVPLLLLMCHCGKG--AKGFTPIPGTIEMLHPWNNEGAPPEDKVVPSFLPVDQGGSLVGRNG--------VGGMAKEATMKGSSSASIVKGQHEMSEMDGRWEEHRSLLSGRATQFTGATGAIMTTETTK-TARATGASRDMAGAQAAAVALNEEFLRNYFTDKAASYTEEDENHTAKDCLLVYSQEETESLNASIG-CCSFIEGELDDRFLDDLGLKFKTLAEVCLGQKIDINKEIEQRQKPATETSMNTASHSLCEQTMVNSENTYSSGSSFPVPKSLQEANAEKVTQEIVTERSVSSRQAQKVATPLPDPMASRNVIATETSYVTGSTMPPTTVILGPSQPQSLIVTERVYAPASTLVDQPYAN--EGTVVVTERVIQPHGGGSNPLEGTQHLQDVPYVMVRERESFLAPSSGVQPTLAMPNIAVG-QNVTVTERVLAPASTLQSSYQIPTENSMTARNTTVSGAGVPGPLP---------------DFGLEESGHSNSTITTSSTRVTKHSTVQHSYS--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "H2EQR6-1", "uniprot_id": "DSG21_DANRE", "id": "H2EQR6-1", "name": "Desmoglein-2.1", "aln": "-----------------------------------------MARRISPVVAFLLCFGLSHFFEAEARLQHSVALHRQKREWIVPPQILEENVDYTKKDFIAKIRSDKEVAHMKYLRYSLRGVGADQEPFNLFVVNPETGYVRITGILDRESISQYNLSGIALFTDGSIAENDIGLRIKVKDQNDNAPVFGVMN-PGAVDELSAVGTEVMRLNCFDADEPGNPNSQIKYEIVDQQPAGQSMFTVENNR-RVVVANPNLDRETVDQYVLLVKASDLNG-APGGNAATGTVTIKINDVNDNVPTLGG-PYEASIEENTEKVEVMRLKVSDLHLKGTDNWEGDCYIASGNEAGYFSIHMDPKTNEAVLMLDKAVDYEDVKDLNLGIGVANKAPFHPSVSGGSQGATISFGGSGGGAGSGAAGGAGAMGGASGSGGGTGASSWSSSGVPLYNVNIKVKNQPEGPKFFPGTKAIPISE-GKAFDSTEIIARYPAIDTDTGKEATNVKYIKSSDPDNWLTIDEKTGAIRMNKAPDRESKYLVNGTYYAKVLSITQDLPSKTATGTIAIQVEDFNDHCPTLISNVQTLCTDKDAVLVTAKDEDAPPNGAPFDFNIVS--EGTAGKWTVEYMNDTTAIFRTHEKLWPGPHELMVEVTDQQGLKCPEPQKLQVDVCTCKNQGGCDRTATGDAKKGSRLGPAGIGLLLLALLALLLIPLLLLLCTCGMT---GAFTDMPFETKVHLISSNTEGQGEDRDVPLMCPPSNVDGMG--------------FMTKDYMAVGAMHSAGLGLGVGAGVGAAGFLESTSTMGGRGYN----EMELDYMNSIG---RNNAYSSRDMAGDFDGMALSDGYLCEYYSQKS-RVVDG---FGK-DDPMVYDYEGKGSPVGSVG-CCSLLEDQNDLEFLNDLGPKFTTLADICGGKKTEIPAPAPAPLPPPPKPVVDRS------EVVSSTTNILNTG--NIATNRVNTVNVASNMATASSTRVENVLVTDNRPTMITSVHPAPTLLVQPQPMYYMVEQQPSTVLVAERPAMTQGMYVLNSGPVAEGMVVQGGNIAANTLTRGERMVLVFRGGPAQALNNGMLHTSNLSGSQLLLVDGGATSGQVLQGTIQRGVAGSQGLMFVDGQGGQVIQGSINNGISTHGGSQNVFYVENKGGSSVVQGGLQMGKASTAGSLIGDVGIGGSSVKITQNPSSHKVVVQERKVVTTQSVK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M2BIB6-1", "uniprot_id": "DSG2L_DANRE", "id": "A0A8M2BIB6-1", "name": "Desmoglein-2-like protein", "aln": "MGVASPLPNTYSAFFGDAAPPTVAAAVADRPLVSPCQSSASNGRRMAKICSISLLVVLSLSILNASASGEQQKKVRQKREWIIPPRKLRENVNYMYLDYIAKIRSDEETR--TSIRYSLKGAGADQPPRDLFTVGSTDGKVKINGLLDREKTPVYYLQGVAKFLNGSNAEKDVDLRVVVLDENDCPPVFNLT--IGAVSELSARDTLVMSITATDADEEGTLHTKIAYSIVEQSHAEMFYINRETGG-IYVMHN-TLDREKIDSYTLTVKGTDMNG-APGGNSGTGKVVINILDVNDNVPTLEKNIYECRVEENTRFVEVVRIQAIDADLIYTDNWLAVFTLVSGNEAGYFSITTDKKTNEGILMLNKELDYEELKEIRLQVSVSNKAHYHSSVV--------------------------------------------ITGSKTYTIQVSVINQPEAPRFKPAVKVITISEESTTVILNKVITNYAAIDSDTMLIATNVRYAKGQDVDNWLIIDEKTADIRLNKIPDYESVFLKNYTYYAHILCITNETPAKTATGTIAIQVKDFNDHCPVLIHQSQKLCYEEHVVFVTAEDKDHFPNAHPFGFKVNT--KHTKESWSVEHFNDTAAIFRSQETLWPGVYHLSVDVWDQQGKVCG-AQLLRVEVCMCGAEKVCLPVTV-----VSRFGGSGVLLMLLGLLLLLLIPLLLLFCLCGAAGAAGDFKAIPFDAKEHLIAYNTEGQGEDKGMALLHMSKDENTR----------------TNVGTVGGAQKQSDGKDGAVTAGGSHWSTFYHYDQFNNNAYHHHRDRTDGDFMYAQ----RKDEHSRFENYNAFDGLALSDAFLGNYYSQKSSHVAQK---QALGDNLKVYEYEGQESRAGSFEDICSLMHEEEDLAFLDNLDMKFKTLAEICSGSTIQRES-----INVSSKKTESKD------LSVQETSNILQSQEKKSSTILAGSVNQSSNMQQTSQEKKTSTIIAGSINQSSSLQHASTGVYLQEQVML------PNTTLLVQQPALYY-------APAAPVYVVEP-----------HPTVLVASG---QVLG----HQENQK-----------------RPKNAKHETHYQSLVYVEQQ--QPLRESQGS-ISGAVHMVNTEIMQSTEGHGVRR------------------EIRPARRVMMEEVREREVDSLHLRVPMSL---", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. . * . : . **** ** .* *.*. : : ****:** : *. * * : * .:*... * :.:..:****. . : * * * *. *: : **: * * ** *** *::.**** * ** :.. ***: . :::: * **. . * : :.. . **** ..* * *:. * ** .. . * *.* *****:*.: * :*** *** *::. * . :*** . :.****.*** * * :***.:: * * :***::*.: : : *:*** :* *: : :.* * *. :* ... : ** . * .: .:* ** * . * * .* ***: :*. *. *:: * ** ** .: * ** .:::.*:: * ** ***: * *:*.**:**.*: :.:* : * ***:* * *. ** *.: .*.: :.*:.::: * * .: . : *.** * * * : ** * * . :* :.: *::*.:* ***:*****:* ** * :* : * . **: :. : .. : . : : : * * .:*:.: * .*:::*: * **. * * .*. **::. : * **::*. **.***::* * . : : . .: . .: . .: . . : . . .: : *.*.:: . .*.: . : * : . *.: .: . . *. . * : : . . : : ", "identical_positions": 230, "similar_positions": 242, "identity": "18.73%" }, { "cls_id": "homologset.agr.MGI:1196608", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A1K0-1", "uniprot_id": "A0A8I6A1K0_RAT", "id": "A0A8I6A1K0-1", "name": "", "aln": "----------------MADATSQLE-----APAPQDVSS-------EFKKPVLPVPPAVRSKAPASSPSVPEDVKK---ECSTAQLDSGCGEPEVSPPQPDSEETGGPPVEQLRSPRVAP---------ASGGPTRAPPYQEPSWGSPATAP--YSLETLKGGTILGTR-TLKDTSYCLFGRLASCDICLEHPSVSRYHAVLQHRGSDP----------------SGDSEDQGQGFYLYDLGSTHGTFLNKTRIPPRTYCRVHVGHVIRFGGSTRLFILQGPEEDREAESELTVTQLKELRKQQQALLEKKMLGEDSDEEDEADTTAGKRNTSGQDEEMGCTWGMGEDAV--EDEAEENPIALEFQQDREAFYIKDPKKALQGFFDREGEELEYEFDEQGHSTWLCRVRLPVDDSTGKQLVAEAIHSGKKKEAMIQCSLEACRILDTLGLLRQEAVSRKRKAKNWEDEDFYDSDDDTFLDRTGLVEKKRLNR----MKKAGKIDEKPETFESLVAKLNDAERELSEISERLKASSKVQSESSSQ-DSLDAFMSEMK-SGSTLDGVSRKKLHLRTFELRKEQQRLKGLIKLVKPAEIP---ELKKTELQTTNAEN-KTKKLALPLFGAMKGGSKFKLKTGTVGKLPPKRPELPPALMQMKDEPEVEEEEEEEEE--EKAKEEHEEG-VEDGGVRLSQGPEPEPEAAGEHPGAPPEPSCSKETKSHEKH---SHMEQSKGYQEMGKIMPSREDPSAAPENECKKDRDELK---KKKS-GPGKFPPILSSKYP-----------------EDDPDYCVWVPPEGQSGDGRTHLNDKYGY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9PX68-1", "uniprot_id": "E9PX68_MOUSE", "id": "E9PX68-1", "name": "", "aln": "----------------MADPTPQLD-----APAPQEVSS-------EFKKPVLPVPSAVRGKAPASSPSVSEDVKK---ECLAAQLDSGCEEPEVPPPQPDSQETGGPPVEQLRSPRVAP---------ASGGPTRAPPYREPSWGSPATAP--YSLETLKGGTILGTR-TLKDTSCCFFGRLASCDICLEHPSVSRYHAVLQHRGADP----------------SGDSEGHEQGFYLYDLGSTHGTFLNKTRIPPRTYCRVHVGHVMRFGGSTRLFILQGPEEDREAESELTVTQLKELRKQQQILLEKKMLGEDSDEEEEANTTEGKSSRSGQDDELGCTWGMGEDAV--EDEAEENPIALDFQQDREAFYIKDPKKALQGFFDREGEELEYEFDEQGHSTWLCRVRLPVDDSTGKQLVAEAIHSGKKKEAMVQCSLEACRVLDTLGLLRQEAVSRKRKAKNWEDEDFYDSDDDTFLDRTGLVEKKRLNR----MKKAGKLDEKPETFESLVAKLNDAERELAEISERLKASSKVLSEPSSQ-DSLDAFMSEMK-SGSTLDGVSRKKLHLRTFELRKEQQRLKGLIKLVKPAEIP---ELKKTELQTTNAEN-KTKKLALPLFGAMKGGSKFKLKTGTVGKLPPKRPELPPALMQMKDEPEVEEEEEEEEEEEEKVKEEHEER-VEDGGVRLLQEPELELEAAVEHPSAPSEPSCSKETKSHESISQLSQVEQSKDYQEMGKIVSSCEDPSAAPANEYKQDRDEPK---KKKSPGPGKFPPILSSKYP-----------------EDDPDYCIWVPPEGQSGDGRTHLNDKYGY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BWU0-2", "uniprot_id": "NADAP_HUMAN", "id": "Q9BWU0-2", "name": "Kanadaptin", "aln": "----------------MADILSQSE-----TLASQDLSG-------DFKKPALPVSPAARSKAPASSSSNPEEVQK---EGPTALQDSNSGEPDIPPPQPDCGDFRSLQEEQSRPPTAVS---------SPGGPARAPPYQEPPWGGPATAP--YSLETLKGGTILGTR-SLKGTSYCLFGRLSGCDVCLEHPSVSRYHAVLQHRASGP----------------DGECDSNGPGFYLYDLGSTHGTFLNKTRIPPRTYCRVHVGHVVRFGGSTRLFILQGPEEDREAESELTVTQLKELRKQQQILLEKKMLGEDSDEEEEMDTSERKINAGSQDDEMGCTWGMGEDAV--EDDAEENPIVLEFQQEREAFYIKDPKKALQGFFDREGEELEYEFDEQGHSTWLCRVRLPVDDSTGKQLVAEAIHSGKKKEAMIQCSLEACRILDTLGLLRQEAVSRKRKAKNWEDEDFYDSDDDTFLDRTGLIEKKRLNR----MKKAGKIDEKPETFESLVAKLNDAERELSEISERLKASSQVLSESPSQ-DSLDAFMSEMK-SGSTLDGVSRKKLHLRTFELRKEQQRLKGLIKIVKPAEIP---ELKKTETQTTGAEN-KAKKLTLPLFGAMKGGSKFKLKTGTVGKLPPKRPELPPTLMRMKDEPEVEEEEEEEEEE-EKEKEEHEKKKLEDGSLSRPQ-PEIEPEAAVQEMRPPTDLTHFKETQTHENMSQLSEEEQNKDYQDCSKTTSLCAGPSAS-KNEYEKSRGELK---KKKTPGPGKLPPTLSSKYP-----------------EDDPDYCVWVPPEGQSGDGRTHLNDKYGY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F3T1-1", "uniprot_id": "E7F3T1_DANRE", "id": "E7F3T1-1", "name": "", "aln": "MEFDGSELTENIPTETMKTEKSQDPENGKICDSKQDITSTNETADDPFKKPVLTPSLAVK-KSLGPSKKPTEEVSSSVSENTDADHDTKHLLSTAKAKDTKIDPSDHPPSERLKEPRVQPKSKDIRPKIPPAGKFPPLPYTEPPWGAVPDIN--YSFELLKNGAILDTV-PLTHRSYFVVGRLPVCDVSLEHPSISRYHAVVQYRGRAG----------------QEGVVGEERGFYAYDLGSTHGTFINKNKIPPKTYIRLRVGHVLKFGGSTRLFILQGPEFDEEAESEMTVTELRERARKQREELERRMMGDGSDEEEEKEESETSASKN-TSEDAGCSWGMAEEAAPEEDDNEENPFATEFQEDQEAAYLKDPKKALQGFYDREGEELEFEYEDKAHGTWLCRIKLPVDDAVGRQLVAEVTHTGKKKEAAVQCCLEACRILEARGLLRQEAVSRKRKKKNWEDDDFYDSDDDTFLDRTGVVEKKRTER----MKKAGKIQERPDTYESLLAKLADVEKELADTEKKLNLSGKGGSGSSTE-DPLDAFMTAVR-SEVALDGVERKKLHLHIADLKKEGQRLSRLVELAKPTQLP---SLLSSGSHTQSSDSDKPKKLSLPMFGAMKGGSKFKLKTGTIGNLPPKRTSLPPELFTMKEMPPGGEEEVEEEEN------SEAEDVVTDGDMEVIQ----SVETAISEHSADSAESQTQQPK-----------EEHEDQPAKTVISPKKDDPSPKGVNNKASNVQNPKTCAKKKVIGPSKPPVTMSKQYP-----------------EDDPDYCVWVPPSGQTGDGRTHLNDKYGY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E2QCZ5-1", "uniprot_id": "E2QCZ5_DROME", "id": "E2QCZ5-1", "name": "FHA domain-containing protein", "aln": "---------------------------------------------------------MNEFKVPAPLPKPKVIITE----------------------KPRSEVPAEPPPPPLKIPKTPK-----------SSPAAVCPYKVPKWSAPPAENQIYSFEVLKSGQIIDTVHQLQQQAVWTFGRLPENDVPAAHPTISRFHVVLQYKPKAPPKPETAKEDDEMEEEDEEPKNDQPEGWYIYDMGSTHGTFLNKQRVPPKVYIRMRVGHMLKLGGSTRVYILQGPGEDEEPESELSVTELRQKR-------EKELADAAVERELRLLEAEER------ERNEGVSWGMGDDAD-EETDLSHNPYASTNNEE---LFFDDPKKTLRGFFEREGLNLEYKCDELSTGSFVCRVELPLDDSNGRPIIVEVNHKGRKKDCVVQCALEACRTLDRHGVLRQANQEAQKRKQLKNRD---SDDEDEFWDRTGDVARKKQRKDNAGVSVTLTYEDLLKQEIDLNMEMEKVEQEISTYQQNEKKLKELAAKQQAEGDDLDNFMDMLTKDVEQLDKTEIKKLRLEQQRIKGEQQKVERLLKIAKPTALPFTTSLAAGSKESAAQEGGAAKKKQLPMIGKRNQFSKFKVVKASPSTQTMTQSNAFASDEEEVEEEEVKEKVKEKEAEVDNLEKEETEPESTTKPSTPENDSLKETKLPAQPEESKPTVAKTEVLKPENVRSTKVSTEAPPAPSHTVASTNPDEDMSTPVEDSSAPAEDITARANDTSEPEEAQKKRRQRQRQRNKQRQDVDMDLDELAEHEDTEKYAKWVPPTNQSGDGITHLNEKFGY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * .. . : . .. : * . .. ** * *.. . **:* **.* *:.* * : .***. *: **::**:*.*:*:: . .. *:* **:*******:** ::**:.* *::***::::*****::***** *.*.***::**:*:: *:.: . :.* . : . : * :***.::* * : ..** . ::: ::.****:*:**::*** :**:: :: . .:::**:.**:**: *: ::.*. *.*:**:. :**.***** *: *:*** . ::: : : : ..*:* * **** : :*: .: :. : . :: . .* :: ..*:*:: .:. : : : :: * ** ** : . ** .. ***:*. :: * *::. *:::.**: :* .* .: :. .** **::* : ****: ..: .. . .:.. . : *: *:* .. : : . : . . . . : : : * . *. :. ... .: .: ** .*. **** .*:*** ****:*:**", "identical_positions": 171, "similar_positions": 219, "identity": "20.45%" }, { "cls_id": "homologset.agr.MGI:1196612", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63750-1", "uniprot_id": "RM23_RAT", "id": "Q63750-1", "name": "Large ribosomal subunit protein uL23m", "aln": "------MARNVLYPLYQ---LGGPQ--------------------------------------------------------LRVFRTNFFIQLVRPGTAQPEDTVQFRIPMEMTRVDLRNYLEQIYNVPVAAVRTRVQHGSNRRRDHKNVRIKKPDYKVAYVQLAHGQTFTFPD--------LFPEKEPTSPD--------PLEEELPQQRQSSD--------PRCPGIPSWFGL------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35972-1", "uniprot_id": "RM23_MOUSE", "id": "O35972-1", "name": "Large ribosomal subunit protein uL23m", "aln": "------MARNVLYPLYQ---LGGPQ--------------------------------------------------------LRVFRTNFFIQLVRPGTAQPEDTVQFRIPMEMTRVDLRNYLEQIYNVPVAAVRTRVQHGSNRRRDHKNVRIKKPDYKVAYVQLAHGQTFTFPD--------LFPEKDPRSPE--------PLEEELPQQRQSSD--------LRCPGIPSWFGL------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q16540-1", "uniprot_id": "RM23_HUMAN", "id": "Q16540-1", "name": "Large ribosomal subunit protein uL23m", "aln": "------MARNVVYPLYR---LGGPQ--------------------------------------------------------LRVFRTNFFIQLVRPGVAQPEDTVQFRIPMEMTRVDLRNYLEGIYNVPVAAVRTRVQHGSNKRRDHRNVRIKKPDYKVAYVQLAHGQTFTFPD--------LFPEKD-ESPEGSAADDLYSMLEEERQQRQSSD--------PRRGGVPSWFGL------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6IQS9-1", "uniprot_id": "RM23_DANRE", "id": "Q6IQS9-1", "name": "Large ribosomal subunit protein uL23m", "aln": "------MAKRIIYPLYQ---LGNPQ--------------------------------------------------------LRIFRPTFNMTLVRPGKEQPPDTVQFRISMAMTKCDVRNYLEKIYSVPVSAVRTRIQYCSNKKRNHLNQRVKRPDYKVAYVQLAQQQTFQFPD--------IFPEKDKKSKEGSVEEMHEKFMEDE-RQRQKPD--------PRRGGVTEWFGL------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W021-1", "uniprot_id": "RM23_DROME", "id": "Q9W021-1", "name": "Large ribosomal subunit protein uL23m", "aln": "------MSTR-WYPIYQ---RGNPQ--------------------------------------------------------LRVFLPNFWMKLIRPTEEQPPNVVTFSVSMEMTKYDVRNYLEKIYKLPVVDVRTRIAMGETKKDQTYGYITKKDDVKLAYVTLPREESFVFPD--------FFSEKAEKQAK-----EEKSLDESKAGFRRFLDR------NKKRPGTPGWFSI------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32387-1", "uniprot_id": "RM41_YEAST", "id": "P32387-1", "name": "Large ribosomal subunit protein uL23m", "aln": "MPRLTVGTKNMLYPLQKTLAVGSCKPEQVPIRSLASVVESSSKILDKSGSDREVDINVSEKIYKWTKAGIEQGKEHFKVGGNKVYFPKARIILLRPNAKHTPYQAKFIVPKSFNKLDLRDYLYHIYGLRAMNITTQLLHGKFNRMNLQTTRFREP--QIKKMTIEMEEPFIWPEEPRPDENSFWDSTTPDNMEKYREERLNCLGSDANKPGTAFDGVVGPYERVAQPFIPRFLKREIDNKRERHAAELQRADKLIALNRYIEDLH", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . **: : *. : ::: .. : *:** :. . * :. :.: *:*:** ** : . : *:: . .: : :. :: : : :.* :*: :: .. . . : .. * . :: ", "identical_positions": 17, "similar_positions": 54, "identity": "6.42%" }, { "cls_id": "homologset.agr.MGI:1196616", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4AEG0-1", "uniprot_id": "D4AEG0_RAT", "id": "D4AEG0-1", "name": "Recombining binding protein suppressor of hairless-like protein", "aln": "MNPGETTDPSVPPGPLTHLSLPDSSEVRLQNDGP--SLLGSWTRSPPEHATILREGVRTCLQQRCEQTVWILHAKVAQKSYGTEKRFFCPPPCVYLAGPGWRVKPMQDQVHQSADTGPTVCGYMGLDGASGSAPETQKLNFEEQPDSREFGCAKTLFISDADKRKHFRLVLRLVQRGGRELGTFHSRLIKVISKPSQKKQSLKNTDLCISSGSKVSLFNRLRSQTVSTRYLSVEDGAFVASARQWAAFTLHLADG-HCSQGDFPPQEGYIRYGSLVQLVCTVTGITLPPMIIRKVAKQCALLDVDEPISQLHKCAFQFPGDTPGGAGTYLCLSTEKVVRFQASLCPKEANRALLNDSSCWTIIGTESVEFSFSTSLACTPEPVTPVPHISTLELSGGGDVATLELHGENFHAGLKVWFGDVEAETMYRSPRSLVCVVPDVAAFGSDWRWLRTPITVPVSLLRADALFYPSAFSFTYTPEYSTRPRPPNAQEPAPDADALLESIHHEFTRTNFHLFCPT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O08674-1", "uniprot_id": "RBPJL_MOUSE", "id": "O08674-1", "name": "Recombining binding protein suppressor of hairless-like protein", "aln": "MDPRETTDPSLPPGPLTHLSLPDSSEVRLQSDGP--SLLGSWTRSPPEHAIILREGVRTCLQQRCEQTVWILHAKVAQKSYGNEKRFFCPPPCVYLAGPGWRVKPMQDQALQSAETGPTVCGYMGLDGASGSAPETQKLNFEEQPDSREFGCAKTLYISDADKRKHFRLVLRLVLRGGQELGTFHSRLIKVISKPSQKKQSLKNTDLCISSGSKVSLFNRLRSQTVSTRYLSVEDGAFVASARQWAAFTLHLADG-HCSQGDFPPQEGYIRYGSLVQLVCTVTGITLPPMIIRKVAKQCALLDVDEPISQLHKCAFQFPSDTPGGAGTYLCLATEKVVRFQASLCPKEANRALLNDSSCWTIIGTESVEFTFSTSLACTREPVTPVPLISTLELSGGGDVATLELHGENFHAGLKVWFGDVEAETMYRSPRSLVCVVPDVAAFGSDWRWLRTPITVPVSLLRADALFYPSPFSFTYTPEYSALPRLPNAQEPAPDADTLLESIHHEFTRTNFHLFCPT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UBG7-1", "uniprot_id": "RBPJL_HUMAN", "id": "Q9UBG7-1", "name": "Recombining binding protein suppressor of hairless-like protein", "aln": "MDPAGAADPSVPPNPLTHLSLQDRSEMQLQSEADRRSLPGTWTRSSPEHTTILRGGVRRCLQQQCEQTVRILHAKVAQKSYGNEKRFFCPPPCVYLSGPGWRVKPGQDQAHQAGETGPTVCGYMGLDSASGSATETQKLNFEQQPDSREFGCAKTLYISDADKRKHFRLVLRLVLRGGRELGTFHSRLIKVISKPSQKKQSLKNTDLCISSGSKVSLFNRLRSQTVSTRYLSVEDGAFVASARQWAAFTLHLADG-HSAQGDFPPREGYVRYGSLVQLVCTVTGITLPPMIIRKVAKQCALLDVDEPISQLHKCAFQFPGSPPGGGGTYLCLATEKVVQFQASPCPKEANRALLNDSSCWTIIGTESVEFSFSTSLACTLEPVTPVPLISTLELSGGGDVATLELHGENFHAGLKVWFGDVEAETMYRSPRSLVCVVPDVAAFCSDWRWLRAPITIPMSLVRADGLFYPSAFSFTYTPEYSVRPGHPGVPEPATDADALLESIHQEFTRTNFHLFIQT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QBJ6-1", "uniprot_id": "A0A8M9QBJ6_DANRE", "id": "A0A8M9QBJ6-1", "name": "Recombining binding protein suppressor of hairless-like protein", "aln": "----------MKINVFVHHREDQSFSSLLK---------------------VTRDSVRQYLQFRPDQSVTILHAKVAQKSYGNEKRFFCPPPCVYLSGHGWKVRQEQLKASGLNESACRIFGYMGLDSSNDPRTDSFKLSFEEQTDKKMFACAKTLYISDTDKRKHFRLLLHLFHNGGQEIGTFNSRLIKVISKPSQKRQSMKNADLCISSGSKVSLFNRLRSQTVSTRYLAVEDGAFVASARQWTAFTVNLVEETQAAHSEYTMCESYICYGCVVQLVCTDSGVALPPMVIRKVNKQQACLDVDEPVSQLHKCAFQFR----GSDHMYLCLSNEKIIQFQASPCPKESNKVSLNDGSCWTIIGTEVVEYSFSESLTGHPATISPVPVISGLELNGGGHVAMLELHGENFSPHLRVWFGNMEAETMFRSSRSLLCVVPDVSILSGEWRWTRQPITVPLSLIRLDGLIYRSWFSFTYTPEHSPSSQTSGSAERSADSDALIDTIHQEFTRTNFHLFMQS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . :.* : . *: : * .** ** : :*:* ************.*************:* **:*: * :. ::. : ******.:... .:: **.**:*.*.: *.*****:***:********:*:*. .**:*:***:*************:**:**:**************************:*************:***::*.: :.::.::. *.*: **.:****** :*::****:**** ** * ******:********** *. ****:.**:::**** ****:*:. ***.********* **::** **: .::*** ** ***.***.** ******** . *:****::*****:**.***:******: : .:*** * ***:*:**:* *.*:* * ********:* . .. * :.*:*:*:::**:********** :", "identical_positions": 290, "similar_positions": 118, "identity": "55.98%" }, { "cls_id": "homologset.agr.MGI:1196617", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P70617-1", "uniprot_id": "NINJ1_RAT", "id": "P70617-1", "name": "Ninjurin-1", "aln": "------------------------------------------------------------------------------------------MDPGTEEYELNGDLRPGSPGSPDASPPR-WGLRNRPINVNHYANKKSAAESMLDIALLMANASQLKAVVEQGNEFAFFVPLVVLISISLVLQIGVGVLLIFLVKYDLNNPAKHAKLDFLNNLATGLVFIIVVVNIFITAFGVQKPVMDVAPRQ------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70131-1", "uniprot_id": "NINJ1_MOUSE", "id": "O70131-1", "name": "Ninjurin-1", "aln": "------------------------------------------------------------------------------------------MESGTEEYELNGDLRPGSPGSPDALPPR-WGLRNRPINVNHYANKKSAAESMLDIALLMANASQLKAVVEQGNDFAFFVPLVVLISISLVLQIGVGVLLIFLVKYDLNNPAKHAKLDFLNNLATGLVFIIVVVNIFITAFGVQKPVMDVAPRQ------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92982-1", "uniprot_id": "NINJ1_HUMAN", "id": "Q92982-1", "name": "Ninjurin-1", "aln": "------------------------------------------------------------------------------------------MDSGTEEYELNGGLPPGTPGSPDASPAR-WGWRHGPINVNHYASKKSAAESMLDIALLMANASQLKAVVEQGPSFAFYVPLVVLISISLVLQIGVGVLLIFLVKYDLNNPAKHAKLDFLNNLATGLVFIIVVVNIFITAFGVQKPLMDMAPQQ------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IDX9-1", "uniprot_id": "NINJ1_DANRE", "id": "A0A0R4IDX9-1", "name": "Ninjurin-1", "aln": "------------------------------------------------------------------------------------------MAS--EAMELNGGVN--RRDDPGARPQQGRMSRNTPLNMNHYANKKSAAESMLDIALLMANASQLKTVLELGPSFSFYIPLITLISISLTLQIIVGILLIFIVKWNLNDSSKHYILNLLENIVTALVFIVVVVNVFITAFGVQRPDDKTS---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8MPP0-1", "uniprot_id": "NIJA_DROME", "id": "Q8MPP0-1", "name": "Ninjurin-A", "aln": "MSNLEHITLEMDKVPLGDNKTLVRNTENISKHSYGGAIDGRTRNTLRVPRAVPETDDDDNDDRPFVKDGNDNPGVDDGLFSTVGGNGGNGGNVNVNVPNGGRRPSFSFPGYNGPGFVTINGVETPIPDVNAYQHKKTLAQGMMDLALLSANANQLRYVLETSSQHPYFYPSLLFISLSIIFQIAVGVGLILNGQYNIKNGHDICRANRINNYTVSGIFIVTVVNVLISAFTVDRDTVPALPANTT----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A8JQY7-1", "uniprot_id": "A8JQY7_DROME", "id": "A8JQY7-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------MASGLQRVNENEMKAMDANRYATKKTIAQGMLDIALLTANASQLKYILQVGEQHQFYKLMLILISLSIVMQLLVGILFVVIGSLNINRQQDQTAAVILNDVILVVVFIISVVNVIISGFGIEYSSQPLRLLDQHEKTP", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : * * **: *:.*:*:*** ***.**: ::: . .. :: : :**:*: :*: **: ::. . ::: . ::: :**: ***::*:.* :: ", "identical_positions": 28, "similar_positions": 44, "identity": "11.24%" }, { "cls_id": "homologset.agr.MGI:1196620", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q05511-1", "uniprot_id": "HEPS_RAT", "id": "Q05511-1", "name": "Serine protease hepsin", "aln": "--MAKE--------------------GGRTAPCCSRPKVAALTVGTLLFLTGIGAASWAIVTILLRSDQEPLYQVQLSPGDSRLLVLDKTEGTWRLLCSSRSNARVAGLGCEEMGFLRALAHSELDVRTAGANGTSGFFCVDEGGLPLAQRLLDVISVCDCPRGRFLTATCQDCGRRKLPVDRIVGGQDSSLGRWPWQVSLRYDGTHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFAGAVARTSP--HAVQLGVQAVIYHGGYLPFRDPTIDENSNDIALVHLSSSLPLTEYIQPVCLPAAGQALVDGKVCTVTGWGNTQFYGQQAVVLQEARVP---------IISNEVCNSPDFYGNQIKPKMFCAGYPEGGIDACQGDSGGHFVCEDRISGTSRWRLCGIVSWGTGCALARKPGVYTKVIDFREWIFQAIKTHSEATGMVTQP-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35453-1", "uniprot_id": "HEPS_MOUSE", "id": "O35453-1", "name": "Serine protease hepsin", "aln": "--MAKEDEEPGAHRGGSTCSRPQPGKGGRTAACCSRPKVAALIVGTLLFLTGIGAASWAIVTILLQSDQEPLYQVQLSPGDSRLAVFDKTEGTWRLLCSSRSNARVAGLGCEEMGFLRALAHSELDVRTAGANGTSGFFCVDEGGLPLAQRLLDVISVCDCPRGRFLTATCQDCGRRKLPVDRIVGGQDSSLGRWPWQVSLRYDGTHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFAGAVARTSP--HAVQLGVQAVIYHGGYLPFRDPTIDENSNDIALVHLSSSLPLTEYIQPVCLPAAGQALVDGKVCTVTGWGNTQFYGQQAMVLQEARVP---------IISNEVCNSPDFYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISGTSRWRLCGIVSWGTGCALARKPGVYTKVTDFREWIFKAIKTHSEASGMVTQP-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P05981-1", "uniprot_id": "HEPS_HUMAN", "id": "P05981-1", "name": "Serine protease hepsin", "aln": "--MAQKE-------------------GGRTVPCCSRPKVAALTAGTLLLLTAIGAASWAIVAVLLRSDQEPLYPVQVSSADARLMVFDKTEGTWRLLCSSRSNARVAGLSCEEMGFLRALTHSELDVRTAGANGTSGFFCVDEGRLPHTQRLLEVISVCDCPRGRFLAAICQDCGRRKLPVDRIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFAGAVAQASP--HGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCLPAAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVP---------IISNDVCNGADFYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKPGVYTKVSDFREWIFQAIKTHSEASGMVTQL-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A8DZG9-1", "uniprot_id": "A8DZG9_DANRE", "id": "A8DZG9-1", "name": "", "aln": "MNMSEKK------------------VGRPGMSIFSPCRVVAAVSLILIILGGLGAAIWALVTYLRTTEDTGLFDVQVSAADQRLRVFDSTQWRWKYVCSSSVNQLIANITCEEMGFVRAVNFSVTCAPESGGD--RDFFCVKESELTYGKKIKTALYPCKCDKGQILEVICQDCGRRMLPEERIVGGVDARQGSWPWQVSLQYDGVHQCGGSIISDRWIISAAHCFPERYRHASRWRVLMGSIYNTPIRKNVVIAEVKTVVYHSSYLPFVDANIDDNSRDIAVISLTKPLQFTDYIQPVCLPTYGQRLADGQMGTVTGWGNVEYYGTQANVLQEAHVP---------IISDAVCNGPDYYDNQVTTTMFCAGYEKGGTDSCQGDSGGPFVAADVLSKTSRYRLLGVVSWGTGCAMAKKPGVYTRVSRFLPWISTAMRMYENSPGVHKMARAATP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1ZBU1-1", "uniprot_id": "A1ZBU1_DROME", "id": "A1ZBU1-1", "name": "trypsin", "aln": "-----------------------------------------------------------------------------------------------------------MYSTKFLWWLMALVAYAGATPTPGDG-------------------------------------------------RIVGGEVATIQEFPYQVSVQLQGRHICGGAIIGIDTVLTAAHCFEDP-WSSADYTVRVGSSEHESG---GHVLSLRRVIAHGDYNPQ------SHDNDLALLILNGQLNFTEHLQPVPLAALADPPTADTRLQVSGWG---FQAEESAVSGEVGVSPQLRFVDVDLVESNQCRRAYSQVLPITRRMICAARP--GRDSCQGDSGGPLVGYAAEEGP--ARLYGIVSWGLGCANPNFPGVYTNVAAFRSWIDEQLDARGWDELLAGWSRLQ--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :: *: . .* . ***** : :*:***:: :* * ***:::. :::***** : : : * *: . . :: *: *..* * .:..*:*:: *. * :*:::*** *.: .: . . *:*** : . :: * *. *. ::.. *. . :. *:**. * *:******* :* . . ** *:**** *** .. *****.* * ** : : ", "identical_positions": 76, "similar_positions": 77, "identity": "16.74%" }, { "cls_id": "homologset.agr.MGI:1196624", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4KLL0-1", "uniprot_id": "TCEA1_RAT", "id": "Q4KLL0-1", "name": "Transcription elongation factor A protein 1", "aln": "--MEDEVVRIAKKMDKMVQKKNAAG-ALDLLKELKNIPMTLELLQSTRIGMSVNAIRKQSTDEEVTSLAKSLIKSWKKLLDGPSTDKDSEEKKKE----PAISSQNSPEAREES-------SSSSHVSSRKDETNARDTYVSSFPRAPSTSDSVRLKCREMLAAALRTGDDYVAIGADEEELGSQIEEAIYQEIRNTDMKYKNRVRSRISNLKDAKNPNLRKNVLCGNIPPDLFARMTAEEMASDELKEMRKNLTKEAIREHQMAKTGGTQTDLFTCGKCKKKNCTYTQVQTRSADEPMTTFVVCNECGNRWKFC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P10711-1", "uniprot_id": "TCEA1_MOUSE", "id": "P10711-1", "name": "Transcription elongation factor A protein 1", "aln": "--MEDEVVRIAKKMDKMVQKKNAAG-ALDLLKELKNIPMTLELLQSTRIGMSVNALRKQSTDEEVTSLAKSLIKSWKKLLDGPSTDKDPEEKKKE----PAISSQNSPEAREES-------SSSSNVSSRKDETNARDTYVSSFPRAPSTSDSVRLKCREMLAAALRTGDDYVAIGADEEELGSQIEEAIYQEIRNTDMKYKNRVRSRISNLKDAKNPNLRKNVLCGNIPPDLFARMTAEEMASDELKEMRKNLTKEAIREHQMAKTGGTQTDLFTCGKCKKKNCTYTQVQTRSADEPMTTFVVCNECGNRWKFC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P23193-1", "uniprot_id": "TCEA1_HUMAN", "id": "P23193-1", "name": "Transcription elongation factor A protein 1", "aln": "--MEDEVVRFAKKMDKMVQKKNAAG-ALDLLKELKNIPMTLELLQSTRIGMSVNAIRKQSTDEEVTSLAKSLIKSWKKLLDGPSTEKDLDEKKKE----PAITSQNSPEAREES-------TSSGNVSNRKDETNARDTYVSSFPRAPSTSDSVRLKCREMLAAALRTGDDYIAIGADEEELGSQIEEAIYQEIRNTDMKYKNRVRSRISNLKDAKNPNLRKNVLCGNIPPDLFARMTAEEMASDELKEMRKNLTKEAIREHQMAKTGGTQTDLFTCGKCKKKNCTYTQVQTRSADEPMTTFVVCNECGNRWKFC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P20232-1", "uniprot_id": "TFS2_DROME", "id": "P20232-1", "name": "Transcription elongation factor S-II", "aln": "MSVEEEVFRIQKKMSKMASDGTGQDQALDLLKALQTLNINLDILTKTRIGMTVNELRKSSKDDEVIALAKTLIKNWKRFLASPAPTTPNNSSAKEGSSNNSSASKSTSAAKSSSSISGKDKSSSSSSSKDKEKKGSTSSSQTSFPSG-GMTDAVRIKCREMLATALKIGEVPEGCGE-PEEMAAELEDAIYSEFNNTDMKYKNRIRSRVANLKDPKNPGLRGNFMCGAVTAKQLAKMTPEEMASDEMKKLREKFVKEAINDAQLATVQGTKTDLLKCAKCKKRNCTYNQLQTRSADEPMTTFVMCNECGNRWKFC", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P07273-1", "uniprot_id": "TFS2_YEAST", "id": "P07273-1", "name": "Transcription elongation factor S-II", "aln": "-MDSKEVLVHVKNLEKNKSNDAAVLEILHVLDKEFVP--TEKLLRETKVGVEVNKFKKS-TNVEISKLVKKMISSWKDAINKNKRSRQAQQHHQD--HAPGNAEDKTTVGESVNGVQQPASSQSDAMKQDKYVSTKPRNSKNDGVDTAIYHHKLRDQVLKALYDVLAKESEHPPQSILHTAKAIESEMNKVNNCDTNEAAYKARYRIIYSNVISKNNPDLKHKIANGDITPEFLATCDAKDLAPAPLKQKIEEIAKQNLYNAQGATIERSVTDRFTCGKCKEKKVSYYQLQTRSADEPLTTFCTCEACGNRWKFS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ..**. *::.* .. . *.:*. . .:* .*::*: ** ::*. .: *: *.*.:*..** : :. :: . :...:. ... . :.*. .. * . . .. . :* : : * .* . . . : * .: ..: ** * * :*: . :**.*: :. * :... :* .:::*. :*: :::.*: : : * *. : ** :.*.***::: :* *:********:*** *: *******.", "identical_positions": 66, "similar_positions": 109, "identity": "20.95%" }, { "cls_id": "homologset.agr.MGI:1196625", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q08463-1", "uniprot_id": "FZD1_RAT", "id": "Q08463-1", "name": "Frizzled-1", "aln": "MAEEAVPSESRAAGR-PSLELCAVALPGRREEVGHQDTAGHRRPRAHSRCWARGLLLLLWLLEAPLLLGVRAQPAG----QVSGPGQQRPPPPQPQQGGQQYNGERGISIPDHGYCQPISIPLCTDIAYNQTIMPNLLGHTNQEDAGLEVHQFYPLVKVQCSAELKFFLCSMYAPVCTVLEQALPPCRSLCERA-QGCEALMNKFGFQWPDTLKCEKFPVHGAGELCVGQNTSDKGTPTPSLLPEFWTSNPQHGGGGYRGGYPGGAGPVERGKFSCPRALRVPSYLNYHF-LGEK---DCGAPCEPTKVYGLMYFGPEELRFSRTWIGIWSVLCCASTLFTVLTYLVDMRRFSYPERPIIFLSGCYTAVAVAYIAGFLLEDRVVCNDKFAEDGAR-------TVAQGTKKE-GCTILFMMLYFFSMASSIWWVILSLTWFLAAGMKWGHEAIEANSQYFHLAAWAVPAIKTITILALGQVDGDVLSGVCFVGLNNVDALRGFVLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHDGTKTEKLEKLMVRIGVFSVLYTVPATIVIACYFYEQAFRDQWERSWVAQSCKSYAIPCPHLQGGGGVPPHPPMSPDFTVFMIKYLMTLIVGITSGFWIWSGKTLNSWRKFYTRLTNSK---QGETTV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70421-1", "uniprot_id": "FZD1_MOUSE", "id": "O70421-1", "name": "Frizzled-1", "aln": "MAEEAAPSESRAAGR-LSLELCAEALPGRREEVGHEDTASHRRPRADPRRWASGLLLLLWLLEAPLLLGVRAQAAG----QVSGPGQQAPPPPQPQQSGQQYNGERGISIPDHGYCQPISIPLCTDIAYNQTIMPNLLGHTNQEDAGLEVHQFYPLVKVQCSAELKFFLCSMYAPVCTVLEQALPPCRSLCERARQGCEALMNKFGFQWPDTLKCEKFPVHGAGELCVGQNTSDKGTPTPSLLPEFWTSNPQHGGGGYRGGYPGGAGTVERGKFSCPRALRVPSYLNYHF-LGEK---DCGAPCEPTKVYGLMYFGPEELRFSRTWIGIWSVLCCASTLFTVLTYLVDMRRFSYPERPIIFLSGCYTAVAVAYIAGFLLEDRVVCNDKFAEDGAR-------TVAQGTKKE-GCTILFMMLYFFSMASSIWWVILSLTWFLAAGMKWGHEAIEANSQYFHLAAWAVPAIKTITILALGQVDGDVLSGVCFVGLNNVDALRGFVLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHDGTKTEKLEKLMVRIGVFSVLYTVPATIVIACYFYEQAFRDQWERSWVAQSCKSYAIPCPHLQGGGGVPPHPPMSPDFTVFMIKYLMTLIVGITSGFWIWSGKTLNSWRKFYTRLTNSK---QGETTV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UP38-1", "uniprot_id": "FZD1_HUMAN", "id": "Q9UP38-1", "name": "Frizzled-1", "aln": "MAEEEAPKKSRAAGGGASWELCAGALSARLAEEGSGDAGGRRRPPVDPRRLARQLLLLLWLLEAPLLLGVRAQAAGQGPGQGPGPGQQPPPPPQQQQSGQQYNGERGISVPDHGYCQPISIPLCTDIAYNQTIMPNLLGHTNQEDAGLEVHQFYPLVKVQCSAELKFFLCSMYAPVCTVLEQALPPCRSLCERARQGCEALMNKFGFQWPDTLKCEKFPVHGAGELCVGQNTSDKGTPTPSLLPEFWTSNPQHGGGGHRGGFPGGAGASERGKFSCPRALKVPSYLNYHF-LGEK---DCGAPCEPTKVYGLMYFGPEELRFSRTWIGIWSVLCCASTLFTVLTYLVDMRRFSYPERPIIFLSGCYTAVAVAYIAGFLLEDRVVCNDKFAEDGAR-------TVAQGTKKE-GCTILFMMLYFFSMASSIWWVILSLTWFLAAGMKWGHEAIEANSQYFHLAAWAVPAIKTITILALGQVDGDVLSGVCFVGLNNVDALRGFVLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHDGTKTEKLEKLMVRIGVFSVLYTVPATIVIACYFYEQAFRDQWERSWVAQSCKSYAIPCPHLQAGGGAPPHPPMSPDFTVFMIKYLMTLIVGITSGFWIWSGKTLNSWRKFYTRLTNSK---QGETTV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P18537-1", "uniprot_id": "FRIZ_DROME", "id": "P18537-1", "name": "Frizzled", "aln": "-------------------------------------------------MWRQILFILPTLIQGVQRYDQSPLDAS--PYYRSGGGLMAS-------SGTELDG-----LPHHNRCEPITISICKNIPYNMTIMPNLIGHTKQEEAGLEVHQFAPLVKIGCSDDLQLFLCSLYVPVCTILERPIPPCRSLCESA-RVCEKLMKTYNFNWPENLECSKFPVHGGEDLCVAENTTSSASTAATPTRSVAKVTTRKHQTGVESPHRN-IG------FVCPVQLKTPLGMGYELKVGGKDLHDCGAPCH------AMFFPERERTVLRYWVGSWAAVCVASCLFTVLTFLIDSSRFRYPERAIVFLAVCYLVVGCAYVAGLGAGDSVSCREPFPPPVKLGRLQMMSTITQGHRQTTSCTVLFMALYFCCMAAFAWWSCLAFAWFLAAGLKWGHEAIENKSHLFHLVAWAVPALQTISVLALAKVEGDILSGVCFVGQLDTHSLGAFLILPLCIYLSIGALFLLAGFISLFRIRTVMKTDGKRTDKLERLMLRIGFFSGLFILPAVGLLGCLFYEYYNFDEWMIQWHRDICKPFSIPCPAAR----APGSPEARPIFQIFMVKYLCSMLVGVTSSVWLYSSKTMVSWRNFVERLQGKEPRTRAQAYV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *::* *::. . . *. .* * . .* : :* :*.*. *:**:*.:*.:*.** ******:***:**:******** ****: ** :*::****:*.****:**:.:******** * : ** **:.:.*:**:.*:*.******. :***.:**:...:.:.: .. . ..:: * .. . . * * ** *:.* :.*.: :* * ******. *:* .* . * *:* *:.:* ** ******:*:* ** ****.*:**: ** .*. **:**: * * *.: *. *::** :: .**:*** *** .**: ** *:::******:******** :*: ***.******::**::***.:*:**:******** :..:* .*:: ** :** **: ******:*******:** **.:*:***:**:***.** *: :**. ::.* *** *:* .* : **.::**** : .* * * * :**:*** :::**:**..*::*.**: ***:* ** ..: :.:: *", "identical_positions": 270, "similar_positions": 171, "identity": "40.79%" }, { "cls_id": "homologset.agr.MGI:1196627", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P50406-1", "uniprot_id": "5HT6R_HUMAN", "id": "P50406-1", "name": "5-hydroxytryptamine receptor 6", "aln": "------------------MVPEPG-------------------PTANSTPAWG-----------------AGPPSAP---------------------------GGSG--WVAAALCVVIALTAAANSLLIALICTQPALRNTSNFFLVSLFTSDLMVGLVVMPPAMLNALYGRWVLARGLCLLWTAFDVMCCSASILNLCLISLDRYLLILSPLRYKLRMTPLRALALVLGAWSLAALASFLPLLLGWHELG---HARPPVPG------------------------QCRLLASLPFVLVASGLTFFLPSGAICFTYCRILLAARKQAVQVASLTTG--MASQASETLQVPRTPRPGVESAD-------------------SRRLATKHSRKALKASLTLGILLGMFFVTWLPFFVANIVQAVCDCISPGLFDVLTWLGYCNSTMNPIIYPLFMRDFKRALGRFLPCPRCPRERQASLASPSLRTSHSGP-RPGLSLQQVLPLPLPPDSDSDSDAGSGGSSGLRLTAQLLLPGEATQDPPLPTRAAAAVNFFNIDPAEPELRPHPLGIPTN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9R1C8-1", "uniprot_id": "5HT6R_MOUSE", "id": "Q9R1C8-1", "name": "5-hydroxytryptamine receptor 6", "aln": "------------------MVPEPG-------------------PVNSSTPAWG-----------------PGPPPAP---------------------------GGSG--WVAAALCVVIVLTAAANSLLIALICTQPALRNTSNFFLVSLFTSDLMVGLVVMPPAMLNALYGRWVLARGLCLLWTAFDVMCCSASILNLCLISLDRYLLILSPLRYKLRMTAPRALALILGAWSLAALASFLPLLLGWHELG---KARTSAPG------------------------QCRLLASLPYVLVASGVTFFLPSGAICFTYCRILLAARKQAVQVASLTTGTATAGQALETLQVPRTPRPGMESAD-------------------SRRLTTKHSRKALKASLTLGILLSMFFVTWLPFFVASIAQAVCDCISPGLFDVLTWLGYCNSTMNPIIYPLFMRDFKRALGRFVPCVHCPPEHRASPASPSMWTSHSGA-RPGLSLQQVLPLPLPPNSDSDS--ASGGTSGLQLTAQLLLPGEATRDPPPPTRAPTVVNFFVTDSVEPEIRQHPLGSPMN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P31388-1", "uniprot_id": "5HT6R_RAT", "id": "P31388-1", "name": "5-hydroxytryptamine receptor 6", "aln": "------------------MVPEPG-------------------PVNSSTPAWG-----------------PGPPPAP---------------------------GGSG--WVAAALCVVIVLTAAANSLLIVLICTQPALRNTSNFFLVSLFTSDLMVGLVVMPPAMLNALYGRWVLARGLCLLWTAFDVMCCSASILNLCLISLDRYLLILSPLRYKLRMTAPRALALILGAWSLAALASFLPLLLGWHELG---KARTPAPG------------------------QCRLLASLPFVLVASGVTFFLPSGAICFTYCRILLAARKQAVQVASLTTG--TAGQALETLQVPRTPRPGMESAD-------------------SRRLATKHSRKALKASLTLGILLGMFFVTWLPFFVANIAQAVCDCISPGLFDVLTWLGYCNSTMNPIIYPLFMRDFKRALGRFLPCVHCPPEHRPALPPPPCGPLTAVPDQASACSRCCLCLCRQTQIQTPLQGAPRACSSQPSFCCLERPPGTPRHPPGPPLWSTSLSQTLWSLRYGRIHSVPP-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M3ANX4-1", "uniprot_id": "A0A8M3ANX4_DANRE", "id": "A0A8M3ANX4-1", "name": "5-hydroxytryptamine receptor 6", "aln": "MRAEGVKSPTLAGKRWKGLLLQTGHLDLLSHRFRRGGKLFLSLSMNFKKKSWMRVRSEEVRTVLFNSPMMSGSPPIPRVEAASDLWKIHRSFNDSSTISDGWSIGGSGPWLLAVMLSLIILVTACGNILLIALVFAHRSLRCTSNCFLVSLFLSDLMVALVVMPPAMLNVLCGTWVLAPGFCPVWLCFDVMCCSASILNLCVISLDRYLLIISPLRYKQHMTPPRALLLVGGAWGLAALTSFLPIKMDWHSLGRMQELTEDDPGNATHLNSFYPSSYFQLSSSGMPSTQCRLRVTLPFALVATFLTFFLPSTAICFTYCRILLAARRQARQVEALTHP-AYPQHSLGEPSRPPSPGHAIQDGDDYSHQEPPGLRHAPLSVNSERRLAHRQRKRALKASLTLGVLLGLFFSAWLPFFITNMAQAVCECVPPSFFDAITWLGYCNSTMNPIIYPMFMRDFKRALARLLPCCSSSQAPRRPSLPLSLSLRNSGE--PQLPSEPPSLVSDPPQ----------------------LPATATDAVNLLDAEHAGIDLPLLLPNQVDTLDD-------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: :.* . .. :* .*.*. * **** :*. *.::* :**..* ***.*: :: :** *** ****** *****.**********.* * **** *:* :* .**************:*********:****** :**. *** *: ***.****:****: :.**.** . ** **** .:**:.***: :****** **************:** ** :** . :: . * :* .::..* .***: :: ::*********:**.:** :*****::.:.****:*:.*.:**.:****************:*********.*::** .. : . . . : . . : .: * :. : :. ", "identical_positions": 202, "similar_positions": 102, "identity": "35.31%" }, { "cls_id": "homologset.agr.MGI:1196908", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P23881-1", "uniprot_id": "TCEA3_MOUSE", "id": "P23881-1", "name": "Transcription elongation factor A protein 3", "aln": "MGLEEELLRIAKKLEKMVSR-KKTEGALDLLKKLN-SCQMSIQLLQTTRIGVAVNGVRKHCSDKEVVSLAKVLIKNWKRLLDSPRTTKGER------------------------------------------------------------EEREKAKK-EKGLG------------------------------------------------------------------------------------------------------------------------CSDWKPEAG-----------------------LSPP---------------------------------------------------------------------------------------------------------RKKGGGEPKTR---------------------------------------------------------------------------------------------------------RDSVDSRSS------TTSSPKR-------------PSLERSNSSKSKVETPTTPS---SPSTPTFAPAVCLLAPCYLTGDSVRDKCVEMLSAALKAEDNFKDYGVNCDKLASEIEDHIYQELKSTDMKYRNRVRSRISNLKDPRNPGLRRNVLSGAISPELIAKMTAEEMASDELRELRNAMTQEAIREHQMAKTGGTTTDLLRCSKCKKKNCTYNQVQTRSADEPMTTFVLCNECGNRWKFC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F7EY03-1", "uniprot_id": "F7EY03_RAT", "id": "F7EY03-1", "name": "Transcription elongation factor", "aln": "MGLEEELLRIAKKLEKMVAR-KKTEGALDLLKKLN-SCQMSIQLLQTTRIGVAVNGVRKHCSDKEVVSLAKVLIKNWKRLLDSPRTTKGER------------------------------------------------------------EAREKAKKKEKGLG------------------------------------------------------------------------------------------------------------------------SSGWKPEAG-----------------------LSPP---------------------------------------------------------------------------------------------------------RKKEGGEPKTR---------------------------------------------------------------------------------------------------------RDSVDSRSS------TTSSPKR-------------PSLERSNSSRSKVETPKTPS---SPSTPTFAPAVCLLASCYLTGDSVRDKCVEMLSAALKAEDDFKDYGVNCDKLASEIETHIYQELKSTDMKYRNRVRSRISNLKDPRNPGLRRNVLSGTISPELIAKMTAEEMASDELRELRNAMTQEAIREHQMAKTGGTTTDLLRCSKCKKKNCTYNQVQTRSADEPMTTFVLCNECGNRWKFC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75764-1", "uniprot_id": "TCEA3_HUMAN", "id": "O75764-1", "name": "Transcription elongation factor A protein 3", "aln": "MGQEEELLRIAKKLEKMVAR-KNTEGALDLLKKLH-SCQMSIQLLQTTRIGVAVNGVRKHCSDKEVVSLAKVLIKNWKRLLDSPGPPKGEKG-----------------------------------------------------------EEREKAKKKEKGLE------------------------------------------------------------------------------------------------------------------------CSDWKPEAG-----------------------LSPP---------------------------------------------------------------------------------------------------------RKKRE-DPKTR---------------------------------------------------------------------------------------------------------RDSVDSKSS------ASSSPKR-------------PSVERSNSSKSKAESPKTPS---SPLTPTFASSMCLLAPCYLTGDSVRDKCVEMLSAALKADDDYKDYGVNCDKMASEIEDHIYQELKSTDMKYRNRVRSRISNLKDPRNPGLRRNVLSGAISAGLIAKMTAEEMASDELRELRNAMTQEAIREHQMAKTGGTTTDLFQCSKCKKKNCTYNQVQTRSADEPMTTFVLCNECGNRWKFC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B4P3-1", "uniprot_id": "A0A8M2B4P3_DANRE", "id": "A0A8M2B4P3-1", "name": "", "aln": "MTREEDLLRIAKKLDKMVSR-NNMDGALDLLRELK-DFNMTLKLLQDTRIGMSVNGIRKHCTDEDVVNLAKILIKNWKRLLESAQNPKSERPNEVKNGSHPSKPSGSPSRTSPEKDSSLRRSTAEIKPDLDSNKKLDEKQRREKIDAEFRKEKRESNQKKEKQSINNKKDQERKDALNSDHLPSPLTLSSVPLKCPPTGEVKWERKDAPVDFFPPPSINSHPPLRRSSVDVKRKDTQSSVHSPALQSHPPKRPFIDGKKERRDTNDLLFPLHHPLPPPPIPIPKRSSEVKKERKDPPEMLPPPTPVLSTPPPPPKRVLSPPPPPPKRVLSPPPPKHVLSAPSPPLPKRTSLEENKESKERVKKAADPNAPLAPLPFHLHPPQKREMKKERKETVDPSAPFPPVPLHLQPPTPTKRPSLDTKKDKEKERKDTSDPKRRTSEHNERERKDTSDSKRRTSEHNERERKDTADQKRRTSEHNEKERKDTSDPKRQTSVHNDKDRKDTRDNKLLKRPSMKIKIERKDSTDSKKPLPRKPSLDGRRDSKDSTDSKSSNHLLKRQSSEPKLERRDSTNSRSGSSPQAKKSCESKSKPETPKTPTTPTSPLSPSFSSSAGPLSPRLQTGDSIRDKCIEMLTAALRTDDDYKDYGTNCEAMGAEIEDYIYQETKATDMKYKNRVRSRISNLKDPKNPNLRKNVLAGAIELSRIASMTAEEMASDELKQLRNVLTQEAIREHQMAKTGGTTTDLLQCGKCKKKNCTYNQVQTRSADEPMTTFVLCNECGNRWKFC", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P20232-1", "uniprot_id": "TFS2_DROME", "id": "P20232-1", "name": "Transcription elongation factor S-II", "aln": "MSVEEEVFRIQKKMSKMASDGTGQDQALDLLKALQ-TLNINLDILTKTRIGMTVNELRKSSKDDEVIALAKTLIKNWKRFLASPAPTTPNN---------------------------------------------------------------SSAKE------------------------------------------------------------------------------------------------------------------------------GSSNNSSAS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KSTSAAKSS------SSISGKD----------------KSSSSSSSKDKEKKGST---SSSQTSFPSGG--------MTDAVRIKCREMLATALKIGEVPEGCGE-PEEMAAELEDAIYSEFNNTDMKYKNRIRSRVANLKDPKNPGLRGNFMCGAVTAKQLAKMTPEEMASDEMKKLREKFVKEAINDAQLATVQGTKTDLLKCAKCKKRNCTYNQLQTRSADEPMTTFVMCNECGNRWKFC", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P07273-1", "uniprot_id": "TFS2_YEAST", "id": "P07273-1", "name": "Transcription elongation factor S-II", "aln": "-MDSKEVLVHVKNLEKNKSN---DAAVLEILHVLDKEFVPTEKLLRETKVGVEVNKFKKS-TNVEISKLVKKMISSWKDAINKNKRSRQAQ---------------------------------------------------------------QHHQDHAPG--------------------------------------------------------------------------------------------------------------------------NAEDKTTVG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ESVNGVQQP------ASSQSD---------------AMKQDKYVSTKPRNSKNDG----VDTAIY-------------HHKLRDQVLKALYDVLAKESEHPPQSILHTAKAIESEMNKVNNCDTNEAAYKARYRIIYSNVISKNNPDLKHKIANGDITPEFLATCDAKDLAPAPLKQKIEEIAKQNLYNAQGATIERSVTDRFTCGKCKEKKVSYYQLQTRSADEPLTTFCTCEACGNRWKFS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:::: *::.* : .*::*: *. . .:* *::*: ** .:* .: :: *.* :*..** : . . . . :. : : .. :.. : . . : . :* . . . : . :* : : * .* . . . * * .: . .: *: * * :*: . .**.*: :. * : :*. .:::*. ::: : :.:: : : * *. : ** : *.***::: :* *:********:*** *: *******.", "identical_positions": 61, "similar_positions": 106, "identity": "7.77%" }, { "cls_id": "homologset.agr.MGI:1196990", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P04218-1", "uniprot_id": "OX2G_RAT", "id": "P04218-1", "name": "OX-2 membrane glycoprotein", "aln": "-------------------------------------------------------------------------------------------------MGSPVFRRPFCHLSTYSLLWA---IAAVALSTAQVEVVTQDERKLLHTTASLRCSLKTTQEPLIVTWQKKKAVG-PENMVTYSKAHGVVIQPTYKDRINITELGLLNTSITFWNTTLDDEGCYMCLFNMFGSGKVSGTACLTLYVQPIVHLHYNYFED-HLNITCSATARPAPAISWKGTGSGIEN---STESHSHSNGTTSVTSILRVKDPKTQVGKEVICQVLYLGNVIDYKQSLDKGFWFSVPLLLSIVSLVILLVLISILLYWKRHRNQERGESSQGMQRMK-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O54901-1", "uniprot_id": "OX2G_MOUSE", "id": "O54901-1", "name": "OX-2 membrane glycoprotein", "aln": "-------------------------------------------------------------------------------------------------MGSLVFRRPFCHLSTYSLIWG---MAAVALSTAQVEVVTQDERKALHTTASLRCSLKTSQEPLIVTWQKKKAVS-PENMVTYSKTHGVVIQPAYKDRINVTELGLWNSSITFWNTTLEDEGCYMCLFNTFGSQKVSGTACLTLYVQPIVHLHYNYFED-HLNITCSATARPAPAISWKGTGTGIEN---STESHFHSNGTTSVTSILRVKDPKTQVGKEVICQVLYLGNVIDYKQSLDKGFWFSVPLLLSIVSLVILLVLISILLYWKRHRNQERGESSQGMQRMK-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P41217-1", "uniprot_id": "OX2G_HUMAN", "id": "P41217-1", "name": "OX-2 membrane glycoprotein", "aln": "-------------------------------------------------------------------------------------------------MERLVIRMPFSHLSTYSLVWV---MAAVVLCTAQVQVVTQDEREQLYTPASLKCSLQNAQEALIVTWQKKKAVS-PENMVTFSENHGVVIQPAYKDKINITQLGLQNSTITFWNITLEDEGCYMCLFNTFGFGKISGTACLTVYVQPIVSLHYKFSED-HLNITCSATARPAPMVFWKVPRSGIEN---STVTLSHPNGTTSVTSILHIKDPKNQVGKEVICQVLHLGTVTDFKQTVNKGYWFSVPLLLSIVSLVILLVLISILLYWKRHRNQDRGELSQGVQKMT-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N4J1-1", "uniprot_id": "A0A8M1N4J1_DANRE", "id": "A0A8M1N4J1-1", "name": "", "aln": "MFVVSMPRCLQICVSLVMVSRLQGRVSAPARLEALVEQPFTLSCTLVKARGESVHQIRWLDVQNQTLISYQPGQQDSVSGQQHVELAASPRDASAITIKRVSHRDEGCYTCIFDILPKGSREGQTCLTVTATVIPEGNKTAVGGKQITLACRYGLPEKVKQVLWKKIVTKAESREIAFFAKQSDPVIEEEFVERVSLSPS-LSDTQLTLWPVQSEDEACYTCEFHTYPDVIKSATSCLTVFVLPKPQVSYKTTSPGVIEANCTAVARPKAEIVWNVEGNDRTIGPPVTIDVQQSDGTTLVISTLTIQAG-LLKDVSVKCLVHHKGLETAIAVSMNTKIGTALAILISVTTVAFLLVLCLCFCLWKCVLRKDEPEEHQLPRRSRENREADS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * .: . :.:: . . * .: . : :: . :* * .:: * *:* : . ..::. ::: . **: : :::.:: * :: :*:* :**.** * *: : *.*:***::* * : *: . :: .*:*.*** . : *: .. * :.:*** * * * :: . .* * * : * :::. ::.:*:*:.::.:**** : ** .::. * * :: ", "identical_positions": 53, "similar_positions": 96, "identity": "13.59%" }, { "cls_id": "homologset.agr.MGI:1197006", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F7EUG0-1", "uniprot_id": "F7EUG0_RAT", "id": "F7EUG0-1", "name": "", "aln": "MRPYVQKRKKTQEQPGGAFVCLLLRGFCGIMAAQTDLWDAIVIGAGVQGCFTAYHLAQNSKKVLLLEQFLLPHSRGSSHGQSRIIRKAYPEDFYTRMMDECYRTWAQLEREAGAQLHRRTELLFLGMKENPGLKTIQATLSRQGIDHECLSSVHLKQRFPNIRFTKGEVGLLDKTGGVLYADKALRALQHVIRQLGGMVCDGEKVVEIRPGLPVTVKTTLKSYQANSLVITAGPWTNRILRPLGIELPLQTLRINVCYWREKVPGSYSVSQAFPCILSLDLAP--HHIYGLPASEYPGLMKVCYHHGDSVDPEERDCPKTFSDIQDVQILCHFVKDHLPGLRPEPDIMERCMYTNTPDEHFILDCHPKYDNIVIGAGFSGHGFKLAPAVGKVLYELSMKLPPSYDLAPFRISRFSKLSKAHL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D826-1", "uniprot_id": "SOX_MOUSE", "id": "Q9D826-1", "name": "Peroxisomal sarcosine oxidase", "aln": "------------------------------MAAQTDFWDAIVIGAGIQGCFTAYHLAKHSKSVLLLEQFFLPHSRGSSHGQSRIIRKAYPEDFYTMMMKECYQTWAQLEREAGTQLHRQTELLLLGTKENPGLKTIQATLSRQGIDHEYLSSVDLKQRFPNIRFTRGEVGLLDKTGGVLYADKALRALQHIICQLGGTVCDGEKVVEIRPGLPVTVKTTLKSYQANSLVITAGPWTNRLLHPLGIELPLQTLRINVCYWREKVPGSYGVSQAFPCILGLDLAP--HHIYGLPASEYPGLMKICYHHGDNVDPEERDCPKTFSDIQDVQILCHFVRDHLPGLRAEPDIMERCMYTNTPDEHFILDCHPKYDNIVIGAGFSGHGFKLAPVVGKILYELSMKLPPSYDLAPFRMSRFSTLSKAHL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P0Z9-1", "uniprot_id": "SOX_HUMAN", "id": "Q9P0Z9-1", "name": "Peroxisomal sarcosine oxidase", "aln": "------------------------------MAAQKDLWDAIVIGAGIQGCFTAYHLAKHRKRILLLEQFFLPHSRGSSHGQSRIIRKAYLEDFYTRMMHECYQIWAQLEHEAGTQLHRQTGLLLLGMKENQELKTIQANLSRQRVEHQCLSSEELKQRFPNIRLPRGEVGLLDNSGGVIYAYKALRALQDAIRQLGGIVRDGEKVVEINPGLLVTVKTTSRSYQAKSLVITAGPWTNQLLRPLGIEMPLQTLRINVCYWREMVPGSYGVSQAFPCFLWLGLCP--HHIYGLPTGEYPGLMKVSYHHGNHADPEERDCPTARTDIGDVQILSSFVRDHLPDLKPEPAVIESCMYTNTPDEQFILDRHPKYDNIVIGAGFSGHGFKLAPVVGKILYELSMKLTPSYDLAPFRISRFPSLGKAHL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1P8J4-1", "uniprot_id": "A0A8M1P8J4_DANRE", "id": "A0A8M1P8J4-1", "name": "Peroxisomal sarcosine oxidase", "aln": "--------------------------------MSSKVFDCIVIGAGIQGSCTAYQLAKNKQKTLLLEQFVLPHSRGSSHGQTRIIRKAYEEDFYTQMMQESYELWAELEKEAGVELYRRTGLLVMGPEKSEGFSKLKDTMQRHKIPTVFLEKQEFNEHISNVNLSEGNGALIDTFAGVLYAERSLQAVQRLFQCSGGVLKDGQTVTGVSPGAVVTVSTGSAVYRGKSVVITAGPWANTLLAHAGLQLPLKVVKINVCYWKEKIPGTYSVDQSFPCFIQMEPKEGEYDIYGLPSNEYPGLMKVCYHMGSETDPDERD---KQTDRGDIDILARYVTRCLPGLVPAPAVVESCMYTVTPDHHFVLDSHPSYGNIIIGAGFSGHGFKFSPIIGKVLSQLAMGQVPSHDLSPFRIQRFQSQSKSSL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ....:*.******:**. ***:**:: : ******.***********:******* ***** **.*.*. **:**:***.:*:*:* **.:* ::. :..:: .:.*: : *.. .:::::.*:.:..*: .*:*. .**:** ::*:*:* : ** : **:.*. : ** ***.* *:.:*:*******:* :* *:::**:.::******:* :**:*.*.*:***:: : :.*****:.*******:.** *. .**:*** :* *::**. :* **.* . * ::* **** ***.:*:** **.*.**:***********::* :**:* :*:* **:**:***:.** . .*: *", "identical_positions": 186, "similar_positions": 128, "identity": "44.08%" }, { "cls_id": "homologset.agr.MGI:1197007", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JTI9-1", "uniprot_id": "A0A0G2JTI9_RAT", "id": "A0A0G2JTI9-1", "name": "RING-type E3 ubiquitin transferase", "aln": "MAKQWGISLVVKLTKSHEQNYLPGERLLPSPPCRLTMNMVQGSAFLAKLMKSADTFELKYDFSCELYRLSTYSTFPAGVPVSERSLARAGFYYTGVNDKVKCFSCGLMLDNWKQGDSPIEKHRKLYPSCSFVQTLNPANSLEASPQPPLPSTATSTMPSGFAASESTGYFSGSYSSFPSDPVNFRANQDCPAFSTSPYHFAMNTEKARLLTYQTWPLSFLSPAELAKAGFYYTGPGDRVACFACGGKLSNWDRKDDPLSEHRRHFPSCPFLKD--VGQFTSQYTVSNLSMQTH-----------AARVRTFSTWPSSALVHPQELASAGFYYTGHSDDVKCFCCDGGLRCWESGDDPWVEHAKWFPRCEYLIRIKGQEFVGQVQAGYPHLLEQLLSTSDSPEDETGEAAIVHLGPGE-NWEDAVMMNTPVVKAALDMGFSRSLVRQTVQRQILATGENYRTVSDLVIGLLDAEDEMREEQTEQEAEEEESDDLTLIRKNKMVLLQHLTPVTPILDCLLSARVITEQEYDAVKQKPHT-LQARTLIDTVLAKGNTAATSFRNSLQEIDPGLYRDIFVRQNIRSLPTDDIAALPMEEQLRKLQEERTCKVCMDREVSLVFIPCGHLVVCKECAPSLRKCPICRGTIKGTVRTFLS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O08863-1", "uniprot_id": "BIRC3_MOUSE", "id": "O08863-1", "name": "Baculoviral IAP repeat-containing protein 3", "aln": "--------------------------------------MVQDSAFLAKLMKSADTFELKYDFSCELYRLSTYSAFPRGVPVSERSLARAGFYYTGANDKVKCFCCGLMLDNWKQGDSPMEKHRKLYPSCNFVQTLNPANSLEASPRPSLPSTAMSTMPLSFASSENTGYFSGSYSSFPSDPVNFRANQDCPALSTSPYHFAMNTEKARLLTYETWPLSFLSPAKLAKAGFYYIGPGDRVACFACDGKLSNWERKDDAMSEHQRHFPSCPFLKD--LGQSASRYTVSNLSMQTH-----------AARIRTFSNWPSSALVHSQELASAGFYYTGHSDDVKCFCCDGGLRCWESGDDPWVEHAKWFPRCEYLLRIKGQEFVSQVQAGYPHLLEQLLSTSDSPEDENADAAIVHFGPGE-SSEDVVMMSTPVVKAALEMGFSRSLVRQTVQWQILATGENYRTVSDLVIGLLDAEDEMREEQMEQAAEEEESDDLALIRKNKMVLFQHLTCVTPMLYCLLSARAITEQECNAVKQKPHT-LQASTLIDTVLAKGNTAATSFRNSLREIDPALYRDIFVQQDIRSLPTDDIAALPMEEQLRKLQEERMCKVCMDREVSIVFIPCGHLVVCKDCAPSLRKCPICRGTIKGTVRTFLS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13489-1", "uniprot_id": "BIRC3_HUMAN", "id": "Q13489-1", "name": "Baculoviral IAP repeat-containing protein 3", "aln": "------------------------------------MNIVENSIFLSNLMKSANTFELKYDLSCELYRMSTYSTFPAGVPVSERSLARAGFYYTGVNDKVKCFCCGLMLDNWKRGDSPTEKHKKLYPSCRFVQSLNSVNNLEATSQPTFPSSVTNSTHSLLPGTENSGYFRGSYSNSPSNPVNSRANQDFSALMRSSYHCAMNNENARLLTFQTWPLTFLSPTDLAKAGFYYIGPGDRVACFACGGKLSNWEPKDNAMSEHLRHFPKCPFIEN--QLQDTSRYTVSNLSMQTH-----------AARFKTFFNWPSSVLVNPEQLASAGFYYVGNSDDVKCFCCDGGLRCWESGDDPWVQHAKWFPRCEYLIRIKGQEFIRQVQASYPHLLEQLLSTSDSPGDENAESSIIHFEPGEDHSEDAIMMNTPVINAAVEMGFSRSLVKQTVQRKILATGENYRLVNDLVLDLLNAEDEIREEERERATEEKESNDLLLIRKNRMALFQHLTCVIPILDSLLTAGIINEQEHDVIKQKTQTSLQARELIDTILVKGNIAATVFRNSLQEAEAVLYEHLFVQQDIKYIPTEDVSDLPVEEQLRRLQEERTCKVCMDKEVSIVFIPCGHLVVCKDCAPSLRKCPICRSTIKGTVRTFLS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q24307-1", "uniprot_id": "DIAP2_DROME", "id": "Q24307-1", "name": "Death-associated inhibitor of apoptosis 2", "aln": "--------------------------------------------------------MTELGMELESVRLATFGEWPLNAPVSAEDLVANGFFATGNWLEAECHFCHVRIDRWEYGDQVAERHRRSSPICSMVLAPNHCGNVPRSQESDNEGNSVVDSPESCSCP------------------------------------DLLLEANRLVTFKDWPNPNITPQALAKAGFYYLNRLDHVKCVWCNGVIAKWEKNDNAFEEHKRFFPQCPRVQMGPLIEFATGKNLDELGIQPTTLPLRPKYACVDARLRTFTDWPISNIQPASALAQAGLYYQKIGDQVRCFHCNIGLRSWQKEDEPWFEHAKWSPKCQFVLLAKGPAYVSEVLATTAANASSQPATAPAP-----------------TLQADVLMDEAPAKEALALGIDGGVVRNAIQRKLLSSGCAFSTLDELLHDIFDDAGAGAALEVREPPEPSAP----FIEPCQATTSKAASVPIPVADSIPAKPQAAEAVANISK------------ITDEIQKMSVATPNGN------------------------------LSLEEENRQLKDARLCKVCLDEEVGVVFLPCGHLATCNQCAPSVANCPMCRADIKGFVRTFLS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q24306-1", "uniprot_id": "DIAP1_DROME", "id": "Q24306-1", "name": "Death-associated inhibitor of apoptosis 1", "aln": "---------------------MASVVADLPSYGPIAFDQVDNNTNATQLFKNNINKTRMNDLNREETRLKTFTDWPLDW-LDKRQLAQTGMYFTHAGDKVKCFFCGVEIGCWEQEDQPVPEHQRWSPNCPLLRRR-TTNNVPIN-AEALDRILPPISYDICGAN----------------------------------------DSTLEMREHAYAEGVIPMSQLIQS----IGMNAVNAAGSVTGTAAPQPRVTVATHASTATQATGDVQPETCRPSAASGNYFPQYPEYAIE----------TARLRTFEAWPRNLKQKPHQLAEAGFFYTGVGDRVRCFSCGGGLMDWNDNDEPWEQHALWLSQCRFVKLMKGQLYIDTVAAKPVLAEEKEESSSIGG-----------------------------------------------------------------VAVASTQASEEEQQTSLSSEEAVSGDVAPSVAPTAATRIFNKIVEATAVATPSTNSSG------------------------------------------------------------------------STSIPEEKLCKICYGAEYNTAFLPCGHVVACAKCASSVTKCPLCRKPFTDVMRVYFS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:. * *: *: :* . :. ..*. *:: * :.:*. * : :. *: *. .*:: * * :: ..: . : : . :. :. * :: . . * : . . . :: . : . **.:** ** . . **.**::* .* *:** *. ** *:. *:** :** * .:*.:: ** :: * * .. ::: . : . : .* . . . . . : : : : **:* . * . .*:****:..* .**.*: :**:** :.. :*.::*", "identical_positions": 66, "similar_positions": 112, "identity": "10.11%" }, { "cls_id": "homologset.agr.MGI:1197008", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99PP0-1", "uniprot_id": "CCN4_RAT", "id": "Q99PP0-1", "name": "CCN family member 4", "aln": "MRWLLPWT-------LAAVAVLMVGNILATALS--PTPTTMTFTPAPLEETITRPEFCKWPCECP----QAPPRCPLG-VSLITDGCECCKICAQQLGDNCTEAAVCD-PHRGLYCDYSGDRPRYAIGVCAQVVGVGCVLDGVRYTNGESFQPNCRYNCTCIDGTVGCTPLCLSPRPPRLWCRQPRHVRVPGQCCEQWVCDDDARRPRQTALLDTRAFAASGAVEQRYENCIAYTSPWSPCSTTCGLGISTRISNVNARCWPEQESRLCNLRPCDVDIRPHIKAG-------------------------------------------KKCLAVYQPEEATNFTLAGCVSTRTYRPKYCGVCTDNRCCIP----------------YKSKTISVDFQCPEGPG-----------------FSRQVLWINACFCNLSCRNPNDIFADLESYPDFAEIAN------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O54775-1", "uniprot_id": "CCN4_MOUSE", "id": "O54775-1", "name": "CCN family member 4", "aln": "MRWLLPWT-------LAAVAVLRVGNILATALS--PTPTTMTFTPAPLEETTTRPEFCKWPCECP----QSPPRCPLG-VSLITDGCECCKICAQQLGDNCTEAAICD-PHRGLYCDYSGDRPRYAIGVCAQVVGVGCVLDGVRYTNGESFQPNCRYNCTCIDGTVGCTPLCLSPRPPRLWCRQPRHVRVPGQCCEQWVCDDDARRPRQTALLDTRAFAASGAVEQRYENCIAYTSPWSPCSTTCGLGISTRISNVNARCWPEQESRLCNLRPCDVDIQLHIKAG-------------------------------------------KKCLAVYQPEEATNFTLAGCVSTRTYRPKYCGVCTDNRCCIP----------------YKSKTISVDFQCPEGPG-----------------FSRQVLWINACFCNLSCRNPNDIFADLESYPDFEEIAN------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95388-1", "uniprot_id": "CCN4_HUMAN", "id": "O95388-1", "name": "CCN family member 4", "aln": "MRWFLPWT-------LAAVTAAAASTVLATALS--PAPTTMDFTPAPLEDTSSRPQFCKWPCECP----PSPPRCPLG-VSLITDGCECCKMCAQQLGDNCTEAAICD-PHRGLYCDYSGDRPRYAIGVCAQVVGVGCVLDGVRYNNGQSFQPNCKYNCTCIDGAVGCTPLCLRVRPPRLWCPHPRRVSIPGHCCEQWVCEDDAKRPRKTAPRDTGAFDAVGEVEAWHRNCIAYTSPWSPCSTSCGLGVSTRISNVNAQCWPEQESRLCNLRPCDVDIHTLIKAG-------------------------------------------KKCLAVYQPEASMNFTLAGCISTRSYQPKYCGVCMDNRCCIP----------------YKSKTIDVSFQCPDGLG-----------------FSRQVLWINACFCNLSCRNPNDIFADLESYPDFSEIAN------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VVK3-1", "uniprot_id": "Q9VVK3_DROME", "id": "Q9VVK3-1", "name": "", "aln": "MLILLPLLGIFGNGFVAEVEANLSLGFKAIKLPRHPNPANCSVGNTTFAHGVTFKLDCKTQCVCENGRHACSTLCPNEQLPAPEDTISCRSPRLVEVPGHCCKMWLCENPTADVYATCHNSTTSGNWTACSRSCGLGTATRHTTTHAGCHQLSNLRLCENRRCDKDDHEDNKWSRSRPLTHKRKQHRAHSHSHQRYHHHKEHEEPAHRIRKGHECRSIQRLGPARIRLGECVSRKLYRPKLCGRCHRGVKCCAPAVSTTIQVELLCPLNAVDPINYVQRRQANKKRQMKEPQDDEDDDDDDDGDDNVEPEPVLQSAQLWDTVALEPIDQEFLQSHQIQIENKFIAVEWILKCECSTKNCNAGSSNISSNSNSNDNMANTNKYGYYNYKNNNRGRNHETNGEPNEPTNNNAGNNKDNEEDVVDSGNNLDHNDVDNMSSEQQPDIIPYPPSVGESSWKAEKLRQQHHWQQNT", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :** :* * . . * *. * *:. . :.: . : ** * * ... ** :. * .* . :: .:* : :*: * .:*. .. . .*:: *:* . . * .* : . . . * : ::. .: : :.: * : :: * .. :*:: . . . * *:. . *.: * . * : * : : : :: * :* : :* . : . .* *.. .* .. . **.:. . ..: . .. : . *:*..: **:. * : *: ", "identical_positions": 50, "similar_positions": 110, "identity": "10.64%" }, { "cls_id": "homologset.agr.MGI:1197009", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6P6S1-1", "uniprot_id": "Q6P6S1_RAT", "id": "Q6P6S1-1", "name": "RING-type E3 ubiquitin transferase", "aln": "---------------------MENSTVLSNWTKENKEKMKYDFSCELYRMSTYSAFPRGVPVSERSLARAGFYYTGVNDKVKCFCCGLMLDNWKQGDSPTEKHRQFYPSCSFVQTLLSGGLQSAAKNTSPAKSRFAHSLP--LEQG----GIHSSLPSNPLNSRAVEDFS-LRMNPCSYAMSTEEARFLSYSMWPLSFLSPAELAKAGFYYTGPGDRVACFACGGKLSNWEPNDDPLSEHRRHFPHCPFLEN----------TSETQRFSVSNLSMQTH----SARMRTFLYWPSSVLVQPEQLASAGFYYVDHNDDVKCFCCDGGLRCWEPGDDPWIEHAKWFPRCEFLIRMKGQEFVDEIQARYPHLLEQLLSTSDTSEEENADP--PVVHLGPGENW-EDAVMMNTPVVKAALDMGFSRSLVRQTVQRQILATGENYRTVSDIVSALLNAEDERREEEKERQSEETASGDLSLIRKNRMALFQQLTCVIPILDDLLEASVLTKEEHDIIRQKTQIPLQARELIDTILVKGNAAASVFKNSLKEVDSTLYEHLFVEKTMKYIPTEDVSGLSLEEQLRRLQEERTCKVCMDREVSIVFIPCGHLVVCRECAPSLRKCPICRGTIKGTVRTFLS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q62210-1", "uniprot_id": "BIRC2_MOUSE", "id": "Q62210-1", "name": "Baculoviral IAP repeat-containing protein 2", "aln": "MDKTVSQRLGQGTLHQKLKRIMEKSTILSNWTKESEEKMKFDFSCELYRMSTYSAFPRGVPVSERSLARAGFYYTGVNDKVKCFCCGLMLDNWKQGDSPVEKHRQFYPSCSFVQTLLSASLQSPSKNMSPVKSRFAHSSP--LERG----GIHSNLCSSPLNSRAVEDFS-SRMDPCSYAMSTEEARFLTYSMWPLSFLSPAELARAGFYYIGPGDRVACFACGGKLSNWEPKDDAMSEHRRHFPHCPFLEN----------TSETQRFSISNLSMQTH----SARLRTFLYWPPSVPVQPEQLASAGFYYVDRNDDVKCFCCDGGLRCWEPGDDPWIEHAKWFPRCEFLIRMKGQEFVDEIQARYPHLLEQLLSTSDTPGEENADPTETVVHFGPGESS-EDVVMMSTPVVKAALEMGFSRSLVRQTVQRQILATGENYRTVNDIVSVLLNAEDERREEEKERQTEEMASGDLSLIRKNRMALFQQLTHVLPILDNLLEASVITKQEHDIIRQKTQIPLQARELIDTVLVKGNAAANIFKNSLKEIDSTLYENLFVEKNMKYIPTEDVSGLSLEEQLRRLQEERTCKVCMDREVSIVFIPCGHLVVCQECAPSLRKCPICRGTIKGTVRTFLS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13490-1", "uniprot_id": "BIRC2_HUMAN", "id": "Q13490-1", "name": "Baculoviral IAP repeat-containing protein 2", "aln": "MHKTASQRLFPGPSYQNIKSIMEDSTILSDWTNSNKQKMKYDFSCELYRMSTYSTFPAGVPVSERSLARAGFYYTGVNDKVKCFCCGLMLDNWKLGDSPIQKHKQLYPSCSFIQNLVSASLGSTSKNTSPMRNSFAHSLSPTLEHSSLFSGSYSSLSPNPLNSRAVEDISSSRTNPYSYAMSTEEARFLTYHMWPLTFLSPSELARAGFYYIGPGDRVACFACGGKLSNWEPKDDAMSEHRRHFPNCPFLEN----------SLETLRFSISNLSMQTH----AARMRTFMYWPSSVPVQPEQLASAGFYYVGRNDDVKCFCCDGGLRCWESGDDPWVEHAKWFPRCEFLIRMKGQEFVDEIQGRYPHLLEQLLSTSDTTGEENADP--PIIHFGPGESSSEDAVMMNTPVVKSALEMGFNRDLVKQTVQSKILTTGENYKTVNDIVSALLNAEDEKREEEKEKQAEEMASDDLSLIRKNRMALFQQLTCVLPILDNLLKANVINKQEHDIIKQKTQIPLQARELIDTILVKGNAAANIFKNCLKEIDSTLYKNLFVDKNMKYIPTEDVSGLSLEEQLRRLQEERTCKVCMDKEVSVVFIPCGHLVVCQECAPSLRKCPICRGIIKGTVRTFLS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q24307-1", "uniprot_id": "DIAP2_DROME", "id": "Q24307-1", "name": "Death-associated inhibitor of apoptosis 2", "aln": "-------------------------------------MTELGMELESVRLATFGEWPLNAPVSAEDLVANGFFATGNWLEAECHFCHVRIDRWEYGDQVAERHRRSSPICSMVLAPNHCGNVPRSQESDNEGNSVVDSPE----------------------------------SCSCPDLLLEANRLVTFKDWPNPNITPQALAKAGFYYLNRLDHVKCVWCNGVIAKWEKNDNAFEEHKRFFPQCPRVQMGPLIEFATGKNLDELGIQPTTLPLRPKYACVDARLRTFTDWPISNIQPASALAQAGLYYQKIGDQVRCFHCNIGLRSWQKEDEPWFEHAKWSPKCQFVLLAKGPAYVSEVLATTAANASSQPATAPAP-------------------TLQADVLMDEAPAKEALALGIDGGVVRNAIQRKLLSSGCAFSTLDELLHDIFDDAGAGAALEVREPPEPSAP--------------------------------FIEPCQATTSKAASVPIPVADSIPAKPQAAEAVANISK--------------ITDEIQKMSVATPNGNLSLEEENRQLKDARLCKVCLDEEVGVVFLPCGHLATCNQCAPSVANCPMCRADIKGFVRTFLS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q24306-1", "uniprot_id": "DIAP1_DROME", "id": "Q24306-1", "name": "Death-associated inhibitor of apoptosis 1", "aln": "--MASVVADLPSYGPIAFDQVDNNTNATQLFKNNINKTRMNDLNREETRLKTFTDWPLDW-LDKRQLAQTGMYFTHAGDKVKCFFCGVEIGCWEQEDQPVPEHQRWSPNCPLLRRRTTNNVPINAEALDRILPPIS-------------------------------------YDICGANDSTLEMREHAYAEGVIP--MSQLIQSIGMNAVNAAGSVTGTAAPQPRVTVATHASTATQATGDVQPETCRPS---------------AASGNYFPQYPEYAIETARLRTFEAWPRNLKQKPHQLAEAGFFYTGVGDRVRCFSCGGGLMDWNDNDEPWEQHALWLSQCRFVKLMKGQLYIDTVAAKP--------------------------------------VLAEEKEESSSIGG-----------------------------VAVASTQASEEEQQTSLSSEEAVSG----------------------------------------DVAPSVAPTAATRIFNKIVEATAVA--------------------------TPSTNSSGSTS------IPEEKLCKICYGAEYNTAFLPCGHVVACAKCASSVTKCPLCRKPFTDVMRVYFS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:. * *: *: :* . :. ..*. *:: * :.:*. * : :. *: *. .*:: * *.:: . :: . . . * :: . . : *: . . * . . : .. : . . . . :. .. **:*** ** . . **.**::* .* *:** *. ** *: *:** :** * .:*.*: ** ::. : . *: . . :: : . : .* .. ..:. . * . *.* : .. : : : : **:* . * . .*:****:..* :**.*: :**:** :.. :*.::*", "identical_positions": 71, "similar_positions": 123, "identity": "11.2%" }, { "cls_id": "homologset.agr.MGI:1197010", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P63165-1", "uniprot_id": "SUMO1_HUMAN", "id": "P63165-1", "name": "Small ubiquitin-related modifier 1", "aln": "MSD----QEAKPSTEDLGDKKEGEYIKLKVIGQDSSEIHFKVKMTTHLKKLKESYCQRQGVPMNSLRFLFEGQRIADNHTPKELGMEEEDVIEVYQEQTGGHSTV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5I0H3-1", "uniprot_id": "SUMO1_RAT", "id": "Q5I0H3-1", "name": "Small ubiquitin-related modifier 1", "aln": "MSD----QEAKPSTEDLGDKKEGEYIKLKVIGQDSSEIHFKVKMTTHLKKLKESYCQRQGVPMNSLRFLFEGQRIADNHTPKELGMEEEDVIEVYQEQTGGHSTV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P63166-1", "uniprot_id": "SUMO1_MOUSE", "id": "P63166-1", "name": "Small ubiquitin-related modifier 1", "aln": "MSD----QEAKPSTEDLGDKKEGEYIKLKVIGQDSSEIHFKVKMTTHLKKLKESYCQRQGVPMNSLRFLFEGQRIADNHTPKELGMEEEDVIEVYQEQTGGHSTV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7SZR5-1", "uniprot_id": "SUMO1_DANRE", "id": "Q7SZR5-1", "name": "Small ubiquitin-related modifier 1", "aln": "MSD----TETKPSSDG-GEKKDGEYIKLKVIGQDNSEIHFKVKMTTHLKKLKESYSQRQGVPVNSLRFLFEGQRITDNLTPKELGMEDEDVIEVYQEQTGGCRND", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q12306-1", "uniprot_id": "SUMO_YEAST", "id": "Q12306-1", "name": "Small ubiquitin-related modifier", "aln": "MSDSEVNQEAKPEVKP--EVKPETHINLKVS-DGSSEIFFKIKKTTPLRRLMEAFAKRQGKEMDSLRFLYDGIRIQADQTPEDLDMEDNDIIEAHREQIGGATY-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** *:**. . : * :*:*** :..***.**:* ** *::* *::.:*** ::*****::* ** : **::*.**::*:**.::** ** ", "identical_positions": 45, "similar_positions": 31, "identity": "42.86%" }, { "cls_id": "homologset.agr.MGI:1197011", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ER26-1", "uniprot_id": "KCNS2_RAT", "id": "Q9ER26-1", "name": "Delayed-rectifier potassium channel regulatory subunit KCNS2", "aln": "MTRQSLWDLSETDVEDGEIRINVGGFKRRLRSHTLLRFPETRLGRLLLCHSREAILELCDDYDDVQREFYFDRNPELFPYVLHFYHTGKLHVMAELCVFSFSQEIEYWGINEFFIDSCCSYSYHGRKVEPEQEKWDEQSDQESTTSSFDEILAFYNDASKFDGQPLGNFRRQLWLALDNPGYSVLSRVFSVLSILVVLGSIITMCLNSLPDFQIPDSQGNPGEDPRFEIVEHFGIAWFTFELVARFAVAPDFLKFFKNALNLIDLMSIVPFYITLVVNLVVESSPTLANLGRVAQVLRLMRIFRILKLARHSTGLRSLGATLKYSYKEVGLLLLYLSVGISIFSVVAYTIEKEENEGLATIPACWWWATVSMTTVGYGDVVPGTTAGKLTASACILAGILVVVLPITLIFNKFSHFYRRQKQLESAMRSCDFGDGMKEVPSVNLRDYYAHKVKSLMASLTNMSRSSPSELSLDDSLH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35174-1", "uniprot_id": "KCNS2_MOUSE", "id": "O35174-1", "name": "Delayed-rectifier potassium channel regulatory subunit KCNS2", "aln": "MTRQSLWDVSDTDVEDGEIRINVGGFKRRLRSHTLLRFPETRLGRLLLCHSREAILELCDDYDDVQREFYFDRNPELFPYVLHFYHTGKLHVMAELCVFSFSQEIEYWGINEFFIDSCCSYSYHGRKVEPEQEKWDEQSDQESTTSSFDEILAFYNDASKFDGQPLGNFRRQLWLALDNPGYSVLSRVFSVLSILVVLGSIITMCLNSLPDFQIPDSQGNPGEDPRFEIVEHFGIAWFTFELVARFAVAPDFLKFFKNALNLIDLMSIVPFYITLVVNLVVESSPTLANLGRVAQVLRLMRIFRILKLARHSTGLRSLGATLKYSYKEVGLLLLYLSVGISIFSVVAYTIEKEENEGLATIPACWWWATVSMTTVGYGDVVPGTTAGKLTASACILAGILVVVLPITLIFNKFSHFYRRQKQLESAMRSCDFGDGMKEVPSVNLRDYYAHKVKSLMASLTNMSRSSPSELSLDDSLH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9ULS6-1", "uniprot_id": "KCNS2_HUMAN", "id": "Q9ULS6-1", "name": "Delayed-rectifier potassium channel regulatory subunit KCNS2", "aln": "MTGQSLWDVSEANVEDGEIRINVGGFKRRLRSHTLLRFPETRLGRLLLCHSREAILELCDDYDDVQREFYFDRNPELFPYVLHFYHTGKLHVMAELCVFSFSQEIEYWGINEFFIDSCCSYSYHGRKVEPEQEKWDEQSDQESTTSSFDEILAFYNDASKFDGQPLGNFRRQLWLALDNPGYSVLSRVFSILSILVVMGSIITMCLNSLPDFQIPDSQGNPGEDPRFEIVEHFGIAWFTFELVARFAVAPDFLKFFKNALNLIDLMSIVPFYITLVVNLVVESTPTLANLGRVAQVLRLMRIFRILKLARHSTGLRSLGATLKYSYKEVGLLLLYLSVGISIFSVVAYTIEKEENEGLATIPACWWWATVSMTTVGYGDVVPGTTAGKLTASACILAGILVVVLPITLIFNKFSHFYRRQKQLESAMRSCDFGDGMKEVPSVNLRDYYAHKVKSLMASLTNMSRSSPSELSLNDSLR", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** *****:*:::*********************************************************************************************************************************************************************************:******:*************************************************************************************:********************************************************************************************************************************************************************************************:***:", "identical_positions": 467, "similar_positions": 9, "identity": "97.9%" }, { "cls_id": "homologset.agr.MGI:1197012", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A2RUV9-1", "uniprot_id": "AEBP1_RAT", "id": "A2RUV9-1", "name": "Adipocyte enhancer-binding protein 1", "aln": "MAAVRTASLLCGLLALLALCPEGSPQTVLTDDEIQEFLEGFLSEFETQSPPREDDVEAQPLP--------EPTQRARKSKAGGKPR----ADAEAPPEKN----------------------------KDKEKKGKKD-----KGPKAAKH-LEGSTRPTKKPKEKPPKATKKPKEKPPKATKKPKEKPPKATKKPKEKPPKATKRPSAGKRFSTVAPLETPERSLTSPSNPGTRELPEERGRTSLNTWQGQGEETQVEARQHRPEPEEETEMPTLDYNDQIEREDYEDFEYIRRQKQPRPTPSRKR----IWPEPPE-EKTQEPEERKEVDPPLKPLLP---PDYGDGYLIPNYDDLDYYFPHPPPQKPDVGQEVDEEKEELKKPKKEGSSPKEDTEDKWAAEKNKDHKAGPRKGEELEEEWGPVEKIKCPPIGMESHRIEDNQIRASSMLRHGLGAQRGRLNMQAGANEDDYYDGAWCAEDESQTQWIEVDTRRTTRFTGVITQGRDSSIHDDFVTTFFVGFSNDSQTWVMYTNGYEEMTFHGNVDKDTPVLSELPEPVVARFIRIYPLTWNGSLCMRLEVLGCPVTP-VYSYYAQNEVVTTDSLDFRHHSYKDMRQLMKVVNEECPTITRTYSLGKSSRGLKIYAMEISDNPGEHELGEPEFRYTAGMHGNEVLGRELLLLLMQYLCHEYRDGNPRVRNLVQDTRIHLVPSLNPDGYEVAAQMGSEFGNWALGLWTEEGFDIFEDFPDLNSVLWAAEEKKWVPYRVPNNNLPIPERYLSPDATVSTEVRAIISWMEKNPFVLGANLNGGERLVSYPYDMARTP----SQEQLLAAALAAARGEDEDEVSEAQ----------------------------------------------------------------------------------------------------------------ETPDHAIFRWLAISFASAHLTMTEPYRGGCQAQDYTSGMGIVNGAKWNPRSGTFNDFSYLHTNCLELSIYLGCDKFPHESELPREWENNKEALLTFMEQVHRGIKGVVTDEQGIPIANATISVSGINHGVKTASGGDYWRILNPGEYRVTAHAEGYTSSAKICNVDYDIGATQCNFILARSNWKRIREILAMNGNRPILRVDPS-----RPMTPQQRRLQQ----RRLRYRLRMREQMRLRRLNSTT--GPATSPTPALTLPPSPTPGSTSRLWEILPTTAAGWEESETETYTEVVTEF--------------------ETEYGPDLEVEELEEEEEEEEE-MDTGLTFPVTTVETYTVNFGDF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q640N1-1", "uniprot_id": "AEBP1_MOUSE", "id": "Q640N1-1", "name": "Adipocyte enhancer-binding protein 1", "aln": "MAPVRTASLLCGLLALLTLCPEGNPQTVLTDDEIEEFLEGFLSELETQSPPREDDVEVQPLP--------EPTQRPRKSKAGGKQR----ADVEVPPEKN----------------------------KDKEKKGKKD-----KGPKATKP-LEGSTRPTKKPKEKPPKATKKPKEKPPKATKKPKEKPPKATKKPKEKPPKATKRPSAGKKFSTVAPLETLDRLLPSPSNPSAQELPQKRDTPFPNAWQGQGEETQVEAKQPRPEPEEETEMPTLDYNDQIEKEDYEDFEYIRRQKQPRPTPSRRR----LWPERPE-EKTEEPEERKEVEPPLKPLLP---PDYGDSYVIPNYDDLDYYFPHPPPQKPDVGQEVDEEKEEMKKPKKEGSSPKEDTEDKWTVEKNKDHK-GPRKGEELEEEWAPVEKIKCPPIGMESHRIEDNQIRASSMLRHGLGAQRGRLNMQAGANEDDYYDGAWCAEDESQTQWIEVDTRRTTRFTGVITQGRDSSIHDDFVTTFFVGFSNDSQTWVMYTNGYEEMTFYGNVDKDTPVLSELPEPVVARFIRIYPLTWNGSLCMRLEVLGCPVTP-VYSYYAQNEVVTTDSLDFRHHSYKDMRQLMKAVNEECPTITRTYSLGKSSRGLKIYAMEISDNPGDHELGEPEFRYTAGIHGNEVLGRELLLLLMQYLCQEYRDGNPRVRNLVQDTRIHLVPSLNPDGYEVAAQMGSEFGNWALGLWTEEGFDIFEDFPDLNSVLWAAEEKKWVPYRVPNNNLPIPERYLSPDATVSTEVRAIISWMEKNPFVLGANLNGGERLVSYPYDMARTP----SQEQLLAEALAAARGEDDDGVSEAQ----------------------------------------------------------------------------------------------------------------ETPDHAIFRWLAISFASAHLTMTEPYRGGCQAQDYTSGMGIVNGAKWNPRSGTFNDFSYLHTNCLELSVYLGCDKFPHESELPREWENNKEALLTFMEQVHRGIKGVVTDEQGIPIANATISVSGINHGVKTASGGDYWRILNPGEYRVTAHAEGYTSSAKICNVDYDIGATQCNFILARSNWKRIREILAMNGNRPILRVDPS-----RPMTPQQRRMQQ----RRLQYRLRMREQMRLRRLNSTA--GPATSPTPALMPPPSPTPAITLRPWEVLPTTTAGWEESETETYTEVVTEF--------------------ETEYGTDLEVEEIEEEEEEEEEEMDTGLTFPLTTVETYTVNFGDF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IUX7-1", "uniprot_id": "AEBP1_HUMAN", "id": "Q8IUX7-1", "name": "Adipocyte enhancer-binding protein 1", "aln": "MAAVRGAPLLSCLLALLALCPGGRPQTVLTDDEIEEFLEGFLSELEPE--PREDDVEAPPPP--------EPTPRVRKAQAGGKPGKRPGTAAEVPPEKT----------------------------KDKGKKGKKD-----KGPKVPKESLEGSPRPPKKGKEKPPKATKKPKEKPPKATKKPKEKPPKATKKPKEKPPKATKKPPSGKRPPILAPSETLEWPLPPPPSPGPEELPQEGGAPLSNNWQNPGEETHVEAREHQPEPEEETEQPTLDYNDQIEREDYEDFEYIRRQKQPRPPPSRRRRPERVWPEPPE-EKAPAPAPEERIEPPVKPLLPPLPPDYGDGYVIPNYDDMDYYFGPPPPQKPDAERQTDEEKEELKKPKKEDSSPKEE-TDKWAVEKGKDHK-EPRKGEELEEEWTPTEKVKCPPIGMESHRIEDNQIRASSMLRHGLGAQRGRLNMQTGATEDDYYDGAWCAEDDARTQWIEVDTRRTTRFTGVITQGRDSSIHDDFVTTFFVGFSNDSQTWVMYTNGYEEMTFHGNVDKDTPVLSELPEPVVARFIRIYPLTWNGSLCMRLEVLGCSVAP-VYSYYAQNEVVATDDLDFRHHSYKDMRQLMKVVNEECPTITRTYSLGKSSRGLKIYAMEISDNPGEHELGEPEFRYTAGIHGNEVLGRELLLLLMQYLCREYRDGNPRVRSLVQDTRIHLVPSLNPDGYEVAAQMGSEFGNWALGLWTEEGFDIFEDFPDLNSVLWGAEERKWVPYRVPNNNLPIPERYLSPDATVSTEVRAIIAWMEKNPFVLGANLNGGERLVSYPYDMARTP----TQEQLLAAAMAAARGEDEDEVSEAQ----------------------------------------------------------------------------------------------------------------ETPDHAIFRWLAISFASAHLTLTEPYRGGCQAQDYTGGMGIVNGAKWNPRTGTINDFSYLHTNCLELSFYLGCDKFPHESELPREWENNKEALLTFMEQVHRGIKGVVTDEQGIPIANATISVSGINHGVKTASGGDYWRILNPGEYRVTAHAEGYTPSAKTCNVDYDIGATQCNFILARSNWKRIREIMAMNGNRPIPHIDPS-----RPMTPQQRRLQQ----RRLQHRLRLRAQMRLRRLNATTTLGPHTVP-PTLPPAPATTLSTTIEPWGLIPPTTAGWEESETETYTEVVTEFGTEVEPEFGTKVEPEFETQLEPEFETQLEPEFEEEEEEEKEEEIATGQAFPFTTVETYTVNFGDF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F829-1", "uniprot_id": "E7F829_DANRE", "id": "E7F829-1", "name": "Adipocyte enhancer-binding protein 1", "aln": "-MRVLVCAALFALCWILTFA-------------INEELANAPNQRTRSIQMRQSNGVKSNRD--------DLQEGFSEDTQMDEPG-------EEMAEKE----------------------------KPKGKKTPEE-----ILAAKAKKAAEKEAKAKKPKPTKKPKPTKKP--KPPKATKKS--KPPKATKKPKAAKPTTPARETKPTKKPTMEEEEEKLLLELGWDTLSPKETEMEKP-------IGPDHDMHSKKDPTTPPSVKEHMPDNWDSRHEIQEPD-----LIPKVKQP-SSTDDPS----IYLPIPE-EATTTPRT-----------------------IAPWYEEYDY-----------ADLAAKKQEEELEKARKAKEEKAEKLRKMWEEEEEEKRK----------QTALHAEPKKCPPLGLESHRVEDDQILASSSSNLGYSALRGRLNMQNSADEEDVYGGAWCADTEEKEHWFQVDGRREVEFTGVITQGRNSESNNDFVSSFFVAFSNDSREWTVLHDGYAEWLFYGNVDKDTPVMTEFSYPVVARYIRVLPQSWNGSLCMRLEVLGCQLP---TSYATENDVPPTDDLDYRHHNYKEMRQMMKVINEECPNITRIYNIGKSFQGLKMYAMEISDNPGEHEPGEPEFRYTAGLHGNEVLGRELLLLLMQFICKEYNDDNPRVHRLVETVRIHLVPSLNPDAYELAYEMGSEMGNWALGHWTEEGYDIFQNFPDLNSVLWGAEDRGWVPRIVPNHHIPIPENFLN--GSVATETKAIISWMERTPFVLGANLQGGEKLVAYPFDMQRPPRAT-STDGRVGQPVQEYHNMNEETWARIQRQNEG--------------------------------------------------------------------------------------------------------ALRETADENLFRWLATTYAHSHLTLTENHRGSCHTDDITGGQGIINRASWKPVVGSMNDFSYLHTNCFEISIFLGCDKFPHESELPSEWENNREALLAFIEQVHRGIKGVVRDVDGNLLANATVSVEGIKHDVKTASTGDYWRLLNPGEYRVTARADGYSSQTRLCIVGYDANATPCSFTLTKSNWARIQQILAQSGKRPRLVNNIP-----RNANNQVNGGSTGPAGGSQNERLNRIRLMRMRKLRMERMKSSTTTEMTTSTTTTTPEPTTTTT----LGSTSESWYD---------------------------------------WFEQESFNFEHTIDED-----------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1RAC0-1", "uniprot_id": "F1RAC0_DANRE", "id": "F1RAC0-1", "name": "", "aln": "MLGLRNQKTLVVLCLSLLVPSWEVNGLTEHSKSEISHTDREQHVEDRNVTSVEDLLQVKIIPPYATIEVGQHKQLLCKVSSDAKNINWVSPNGEKVLTKHGNLKVHNHGSVLSSLTVLNANLNNAGIYKCVATNGDTESQATVKLDIILKRMRRDTDRKGREKRLKEPKPSKKP--KASKPTKKPKSEKKGKGEKGGKKKGKKNREESTTVATTTVAPTTTVPMEYEEFYDPEPDQYWDEDFPAETTTVARTTTTPTEKTKDFIPDMDEYSQPDSYDDYWKVDEPTPTTSVIAGRPADDDDYWDARSVEMVENLPFPDGKEISSTDNDWQYTTTEEPTVP--------PFENSWYEEYEYG-------------HEKKLEEERERLRKEQEEKEREERKRLEEEERERRIYRP-------PPRVYREPKICPPLGMESHRIDNDQLLTSSVFQHRYGSHRARLNIQASGDDDDMNGGAWCANPEEKVHWIEVDARTLTEFTGVITQGRDDPLESDYVSTYYVAFSNDSREWTFLHDGYAEWLFFGNSDKNTPVLSQFMEPVVARYIRILPQSWNGTMCMRMEILGCPVQDPLSQHQSENEVTRRDNLDYTHHNYLDMEKLMKSISDECPNITRFYSLGKSFKGLEIYAMEITDNPGVHETGEPEFRYTAGYHGNEALGRELLLMFMQYLCKEYKDGNPRVRHLVDETRIHLVPSVNPDGHVKAFEKGSELGSWTLGHWTEDGHDIFQNFPDLNNIYWDSEDKGMVPKLTPNHHIPIPEGILSSNGSIAMETLALISWMESHPFVLGANLQGGEKLVTYPFDMRRLTKESEAMEKKLGSRANRRKRQYEEEEEEPNPYLHIGYHQESYSGPQENHAYDHESYGYHQESYGYHHQSQGYHEETQGYHDETQGYHNENQGYHNENQGYHNENQRYHHEGYSEGYNEGYQEGYPEGYRGGYGEGEQEEEIRMVEDQSLFRWLAISYASTHRTMTQSYQRGCHSDDPTGGMGIVNRAKWKPIPGSMDDFSYLHTNCFELSVFLGCDKFPHQSELLREWEHNREALLTFMAQVHRGIKGVVRDNEGNPITNATVSVEGVNHDVKTGEAGDYWRLLNPGEYRVTARAEGYSPFTRLCVVGFDPGATLCNFDLNKSNWDRIKQIMALHGNKPIRLLSSGSRNGVRHYSHSSNQIPVSNSGDMSRARLRRLRLMRIRRLRQQRLLAQKIIPTTTTVTTTSLPTT---------AETTTVWYDS-----------------------------------LPEIFEENTTPHEEIELTDTLDYN----------YNYNINDY", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * * * . . . :. : : : * * * .: : * . : : * **.:*** *..*.***. : :* . . . . : . : : : * : . * :::. : : . *: : . . *:: :* .: :** :: :* .. .. . *: : : * ***:*:****::::*: :** . .: *.***:* .. ::* .*****: : : :*::** * ..*********:. ..*:*::::*.*****: *.. :** * *.** **:***:::: *****:**: * :***::***:*:*** : .: ::*:* *.**: **.* :*.::** :.:***.*** *.:*** :**::*****:**** ** ********** ****.*******::**::*:**.*.****: **: .*******:***.: * : ***:*.*:** ***:*.***::*****.: * :*:: ** .**:::**** *. .::: *. *:*:*** ********:***:**:**:** * . : : :. : :: . : . *. :***** ::* :* *:*: :: .*:::* *.* **:* *.*:* *:::*********:*:*.:********:*** ***:*:****:*: ********** * :* ::***:**.*::*.***.. *****:**********:*:**:. :: * *.:* .** *.* * :*** **::*:* *::* . * . . . . **. **:*:*. . .: ..: *: * : :* : *. : ", "identical_positions": 354, "similar_positions": 269, "identity": "26.6%" }, { "cls_id": "homologset.agr.MGI:1197013", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QYJ2-1", "uniprot_id": "RASA3_RAT", "id": "Q9QYJ2-1", "name": "Ras GTPase-activating protein 3", "aln": "---------------------MAVEEEG----------LRVFQSVRIKIGEAKNLPSYPGPNK------MRDCYCTVNLDQEEVFRTKIVEKSLCPFYGEDFYCEIPRSFRHLSFYIFDRDVFRRDSIIGKVAIQKEDLQRYHNRDTWFQLQHVDADSEVQGKVHLELRLSEVITDT-------------------------------------------------------------------GVVCHK-------------------------------LAARIFECQGLPIVNGQCDPYATVTLAGPFRSEAKK-TKVKKKTNNPQFDEVFYFEVTRPCSY-------SKKSHFDFEEED-----------VDKLEIRVDLWNASNLKFGD-EFLGELRIPLHVLR--YASSYEAWYFLQPR--DNGSKSVKPD----------------DLGSLRLNVVYTEDHVFSSEYYSPLRDLLLKSADVEPVSASAAHILGEVCRDKQEAAIPLVRLLLHYGRVVPFISAIASAEVKRTQDPNTIFRGNSLTSKCIDETMKLAGMHYLHVTLKPTIEEICQSHKSCEIDPVKLKDGENLENNMESLRQYVDRIFSVITKSGVSCPTVMCDIFFSLREAAAKRFQDDLDVRYTAVSSFIFLRFFAPAILSPNLFQLTPHHTDPQTSRTLTLISKTIQTLGSLSKSKSAS--FKESYMATFYEFFNEQKYADAVKNFLDLISSSGRRDP--------KSIEQPILLKEGFMIKRAQGRKRFGMKNFKKRWFRLTNHEFTYQKSKGDQPLCNIPIENILAVERLEEESFRMKNMFQVIQPERALYIQANNCVEAKDWIDILTKVSQCNQKRLTVFHPSAYLNGHWLCCRASSDTAIGCTPCTGGLPANIQLD----IDGDRETERIYSLFNLYMGKLEKMQEACGSKSVYDGPEQEEYSTFI-------IDDPQ---ETYRTLKQVIAGVGTLEQEHAQYRRNKFKKTRYGSQEHPIGDKSFQNYIRQQSEISTHSI------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60790-1", "uniprot_id": "RASA3_MOUSE", "id": "Q60790-1", "name": "Ras GTPase-activating protein 3", "aln": "---------------------MAVEEEG----------LRVFQSVRIKIGEAKNLPSYPGPNK------MRDCYCTVNLDQEEVFRTKIVEKSLCPFYGEDFYCEIPRSFRHLSFYIFDRDVFRRDSIIGKVAIQKEDLQRYHNRDTWFQLQHVDADSEVQGKVHLELRLSEVITDT-------------------------------------------------------------------GVVCHK-------------------------------LAARIFECQGLPIVNGQCDPYATVTLAGPFRSEAKK-TKVKKKTNNPQFDEVFYFEVTRPCSY-------SKKSHFDFEEED-----------VDKLEIRVDLWNASNLKFGD-EFLGELRLPLKILR--HSSSYEAWYFLQPR--DNGNKSLKPD----------------DLGSLRLNVVYTEDHVFSSEYYSPLRDLLLKSADVEPVSASAAHILGEVCRDKQEAAIPLVRLLLHYGRVVPFISAIASAEVKRTQDPNTIFRGNSLTSKCIDETMKLAGMHYLHVTLKPTIEEICQSHKSCEIDPVKLKDGENLENNMESLRQYVDRIFTVITKSGVSCPTVMCDIFFSLREAAAKRFQDDLDVRYTAVSSFIFLRFFAPAILSPNLFQLTPHHTDPQTSRTLTLISKTIQTLGSLSKSKSAS--FKESYMATFYEFFNEQKYADAVKNFLDLISSSGRRDP--------KSIEQPILLKEGFMIKRAQGRKRFGMKNFKKRWFRLTNHEFTYQKSKGDQPLCNIPIENILAVERLEEESFRMKNMFQVIQPERALYIQANNCVEAKDWIDILTKVSQCNQKRLTVFHPSAYLNGHWLCCRASSDTAAGCTPCTGGLPANIQLD----IDGDRETERIYSLFNLYMGKLEKMQEACGSKSVYDGPEQEEYSTFV-------IDDPQ---ETYKTLKQVIAGVGTLEQEHAQYRRDKFKKTRYGSQEHPIGDKSFQNYIRQQSEISTHSI------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14644-1", "uniprot_id": "RASA3_HUMAN", "id": "Q14644-1", "name": "Ras GTPase-activating protein 3", "aln": "---------------------MAVEDEG----------LRVFQSVKIKIGEAKNLPSYPGPSK------MRDCYCTVNLDQEEVFRTKIVEKSLCPFYGEDFYCEIPRSFRHLSFYIFDRDVFRRDSIIGKVAIQKEDLQKYHNRDTWFQLQHVDADSEVQGKVHLELRLSEVITDT-------------------------------------------------------------------GVVCHK-------------------------------LATRIVECQGLPIVNGQCDPYATVTLAGPFRSEAKK-TKVKRKTNNPQFDEVFYFEVTRPCSY-------SKKSHFDFEEED-----------VDKLEIRVDLWNASNLKFGD-EFLGELRIPLKVLR--QSSSYEAWYFLQPR--DNGSKSLKPD----------------DLGSLRLNVVYTEDHVFSSDYYSPLRDLLLKSADVEPVSASAAHILGEVCREKQEAAVPLVRLFLHYGRVVPFISAIASAEVKRTQDPNTIFRGNSLASKCIDETMKLAGMHYLHVTLKPAIEEICQSHKPCEIDPVKLKDGENLENNMENLRQYVDRVFHAITESGVSCPTVMCDIFFSLREAAAKRFQDDPDVRYTAVSSFIFLRFFAPAILSPNLFQLTPHHTDPQTSRTLTLISKTVQTLGSLSKSKSAS--FKESYMATFYEFFNEQKYADAVKNFLDLISSSGRRDP--------KSVEQPIVLKEGFMIKRAQGRKRFGMKNFKKRWFRLTNHEFTYHKSKGDQPLYSIPIENILAVEKLEEESFKMKNMFQVIQPERALYIQANNCVEAKDWIDILTKVSQCNQKRLTVYHPSAYLSGHWLCCRAPSDSAPGCSPCTGGLPANIQLD----IDGDRETERIYSLFNLYMSKLEKMQEACGSKSVYDGPEQEEYSTFV-------IDDPQ---ETYKTLKQVIAGVGALEQEHAQYKRDKFKKTKYGSQEHPIGDKSFQNYIRQQSETSTHSI------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F916-1", "uniprot_id": "E7F916_DANRE", "id": "E7F916-1", "name": "Ras GTPase-activating protein 2", "aln": "---------------------MAVEEEG----------LRVFQSVKIKIGEAKNIPPYPGPNK------MRDCYCTVNLDQEEVFRTKTIEKSLCPFYGEDFYCEIPRSFRHLSFYIFDRDVFRRDSSIGKVAVKKEDLQKYHGKDHWFPLQPVCADSEVQGKVHLELRLSELITDS-------------------------------------------------------------------GGLCHK-------------------------------LATRVLECQDLPIVNGQCDPYAAVSLLGPSRSEAKK-TKVKRKNNNPQFDEIFFFEVTKPLSF-------TKR-QFDVEEDD-----------VDKLALKVDLWNASNLKFGD-EFLGEVRVPLKVLG--QAGVHDAWYFLQPR--DNGHKSVKAD----------------ELGSLRLNIVYTEDHVFPTEHYNPLRDLLLQSAHVQPVSASAAHILGEVCREKQEAAVPLVRLFLHYGKIVPFLSAIAHAEISRTQDPNTIFRGNSLTSKCIDETMKLAGMHYLRVTLKPIIDEICSDHKPCEIDPVKLKESENLDTNRENLRQYVDRIFSVITSSGVSCPTVMCDIFFSLRESAASRFQVDADVRYTAVSSFIFLRFFAPAILSPNLFHLRPHHPDPCTSRTLTLISKTIQTLGSLAKSKSAN--FKESYMAAFYDYFNEQKYADAVKNFLDLISSSARWDQ--------KSIETPIMLKEGFMIKRAQGRNRFGLKNFKKRWFRLTNHEFTYHKTKGEGALCSIPIENILAVERLEEESFKMKNMFQVIQPERALYIQANNCVEARDWIDILTKVSQCNRKRLSTFHPSAFLNGHWLCCKLSADTAPGCTPCTGGLPANIQLD----VDGDRETERIYSLYSTYMSKLVKMQEACGSKSVYDGPEQEEYSTFV-------IDDPQ---ETYKTLRLVISAVQTLEQQHTQYKRDKFRKTKYGSQEHPIGDQSFQCYIRQQSESSTYSI------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P48423-1", "uniprot_id": "GAP1_DROME", "id": "P48423-1", "name": "GTPase-activating protein", "aln": "MLLKKKRYMFDERDDNNINSPVAVEPSSNNNKMADTREVRIEEQLKVKIGEAKNLSSRNAANTSCSTQGTRDVYCTIALDQEEICRTPTIERTLTPFFGEEHQFKIPRRFRYLTIYLWDRDMKQ-DKPIGKIAIKREELHMYNHKDHWFSLRPVDQDSEVQGMVNVEVAFTEAQQTQSLSEGIDLGQHTLRHHQNLPHHSHQQRAHLNDYKENSELSNIQRASAAAASSSSAAMTLKTRAAGLFGHVHHPPSQTQHFPIINTTSTSSDQLSNWKSHGRFVGVTIKVPACVDLAKKQGTCDPFVVCTAHYSNKHQVTRRTKQRKKTVDPEFDEAMYFDLHIDADAGSTNTTGSNKSAGSLESSANKGYSIYPVGGADLVEIVVSVWHDAHGAMSDKVFLGEVRLPMLNKQEQQAVNPSAWYYLQPRSMTHSSRSLNATPRSCATPPGTRLSVDSTIGSLRLNLNYTADHVFPLATYDDLMNLLLESVDQRPITVSAVSILGELVSGKTEVAQPLVRLFTHTERIAPIIKALADHEISHLTDPTTIFRGNTLVSKMMDEAMRLSGLHYLHQTLRPVLSQIVAEKKPCEIDPSKIKDRSAVDTNLHNLQDYVERVFEAITKSADRCPKVLCQIFHDLRECAGEHFPSNREVRYSVVSGFIFLRFFAPAILGPKLFDLTTERLDAQTSRTLTLISKTIQSLGNLVSSRSSQQTCKEEFTVELYKKFCTEQHVDAVKHFLEVISTPSHASSSVHPAAAAATPLEPVLLKEGLMTKYPTSRKRFG-RQFKQRHFRLTTHSLSYAKSKGKQPICDIPLQEIASVEQLKDKSFKMQNCFKIVHNDRSLIVQTTNCVEEREWFDLLHKICLMNSIRMQYFHPSAFVSGFYSCCGRSDENSPGCKKVLDKTMDYFQMDLVTALDPALDLQRIHTLIMSNMSVLESLLDPLTYHQSLSQTQHQQHNPLVPLATDLQKHSPQAFAEFKRTIEKLREKAYAIDRDHRDYKQGITRQLKYGSRQAPIGDDNYWHMMRAAGQLNQQHHQQQQHQQQQQQQQQQQLQQFQPQPVLPQMQNVRAYPYQPATSNMNAYCLHNMQYQQQRLPFHQQQQQHHQQLQQQQSQFQPLRSHQLQRHNNNLNNNNCGNGSSSSPSSTTSSVVAAPPSTTSSSQPAPPIY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 314, "similar_positions": 317, "identity": "26.95%" }, { "cls_id": "homologset.agr.MGI:1197015", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VIB2-1", "uniprot_id": "DAXX_RAT", "id": "Q8VIB2-1", "name": "Death domain-associated protein 6", "aln": "----------------------------------------------------------------------------------------------MATDDSIIVLDDDDEDEAAAQPGPSNPASNPVSPGP------EASGPSESHGDGGSSN---------------------------------------SGSRKCYKLENEKLFEEFLELCKMQTSDHPEVVPFLHKLQQRAQSAFLASAEFRNILSRVLSRSRNRPAKLYVYINELCTVLKAHSIKKK---LNLAPAAS--AESSGDNPPTDPPSDLTNTETTASEASR----TRGSRRQIQRLEQLLALYVAEIQRLQEKELDLS--------------------------------------------ELDDPDSSYLQEARLKRKLIRLFGRLCDLKDCSSLTGKVIEQRIPYRGTRYPEVNRRIER-------------LINKP-GPDTFPDYG--DVLRAVEKAATRHSLGLPRQQLQLLAQDAFRDVGVRLQERRHLDLIY-NFGCHLTDDYRPGVDPALTDPTLARRLRENRTLAMSRLDEVISKYAMMQDKSEEGE------RQKRRARLLATS-QSSDLPKASSDSGEGPSGVASQEDPTTPKAETEDEEDDEESDDE-------EEEEEEEEEEATE-DEDEDLEQLQEDQD-DEEEEEGD-------------------------NEDDKSPASPSPIFRRKEFSNPQKGSGP-QEEQQERGLTGTPASPLEASPGLPSTDAESSGEQLQERLLAGESPVSQLSELDMEALPEETI--PSPEERGISSSRRKSDSSLPTILENGAAMVTSTSFNGRVSSHPCRDASPPSKRFRKEKKQLGPGPLGNSYVKKQTMAQQDSGWKISVLSTPSSPLAS-----VGPVADSSTRVD--------SPSHELVTSSLCNPSPSLILQTPQSQSPRPCIYKTSVATQCDPEEIIVLSDSD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35613-1", "uniprot_id": "DAXX_MOUSE", "id": "O35613-1", "name": "Death domain-associated protein 6", "aln": "----------------------------------------------------------------------------------------------MATDDSIIVLDDDDEDEAAAQPGPSNLPPNPASTGPGPGLSQQATGLSEPRVDGGSSN---------------------------------------SGSRKCYKLDNEKLFEEFLELCKTETSDHPEVVPFLHKLQQRAQSVFLASAEFCNILSRVLARSRKRPAKIYVYINELCTVLKAHSIKKK---LNLAPAASTTSEASGPNPPTEPPSDLTNTENTASEASR----TRGSRRQIQRLEQLLALYVAEIRRLQEKELDLS--------------------------------------------ELDDPDSSYLQEARLKRKLIRLFGRLCELKDCSSLTGRVIEQRIPYRGTRYPEVNRRIER-------------LINKP-GLDTFPDYG--DVLRAVEKAATRHSLGLPRQQLQLLAQDAFRDVGVRLQERRHLDLIY-NFGCHLTDDYRPGVDPALSDPTLARRLRENRTLAMNRLDEVISKYAMMQDKTEEGE------RQKRRARLLGTAPQPSDPPQASSESGEGPSGMASQECPTTSKAETDDDDDDDDDDDEDNEESEEEEEEEEEEKEATE-DEDEDLEQLQEDQGGDEEEEGGD-------------------------NEGNESPTSPSDFFHRR-NSEPAEGLRT-PEGQQKRGLTETPASPPGASLDPPSTDAESSGEQLLEPLLGDESPVSQLAELEMEALPEE---------RDISSPRKKSEDSLPTILENGAAVVTSTSVNGRVSSHTWRDASPPSKRFRKEKKQLGSGLLGNSYIKEP-MAQQDSGQNTSVQPMPSPPLAS-----VASVADSSTRVD--------SPSHELVTSSLCSPSPSLLLQTPQAQSLRQCIYKTSVATQCDPEEIIVLSDSD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UER7-1", "uniprot_id": "DAXX_HUMAN", "id": "Q9UER7-1", "name": "Death domain-associated protein 6", "aln": "----------------------------------------------------------------------------------------------MATANSIIVLDDDDEDEAAAQPGPSHPLPNAASPGA------EAPSSSEPHGARGSSS---------------------------------------SGGKKCYKLENEKLFEEFLELCKMQTADHPEVVPFLYNRQQRAHSLFLASAEFCNILSRVLSRARSRPAKLYVYINELCTVLKAHSAKKK---LNLAPAATTSNEPSGNNPPTHLSLDPTNAENTASQSPR----TRGSRRQIQRLEQLLALYVAEIRRLQEKELDLS--------------------------------------------ELDDPDSAYLQEARLKRKLIRLFGRLCELKDCSSLTGRVIEQRIPYRGTRYPEVNRRIER-------------LINKP-GPDTFPDYG--DVLRAVEKAAARHSLGLPRQQLQLMAQDAFRDVGIRLQERRHLDLIY-NFGCHLTDDYRPGVDPALSDPVLARRLRENRSLAMSRLDEVISKYAMLQDKSEEGE------RKKRRARLQGTSSHSADTPEASLDSGEGPSGMASQGCPSASRAETDDEDDEESDEEE-------EEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAG--------------------KDGDKSPMSSLQISNEKNLEPGKQISRS-SGEQQNKGRIVSPSLLSEEPLAPSSIDAESNGEQPEELTLEEESPVSQLFELEIEALPLDT---PSSVETDISSSRKQSEEPFTTVLENGAGMVSSTSFNGGVSPHNWGDSGPPCKKSRKEKKQTGSGPLGNSYVERQRSVHEKNGKKICTLPSPPSPLAS-----LAPVADSSTRVD--------SPSHGLVTSSLCIPSPARLSQTPHSQPPRPGTCKTSVATQCDPEEIIVLSDSD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58HYH8-1", "uniprot_id": "A0AC58HYH8_DANRE", "id": "A0AC58HYH8-1", "name": "Death domain-associated protein 6", "aln": "-------------------------------MLLTNKRKESVWHVRIKELQSSNQKVNADFET-----PVWILTVLINSMLSAQQIRSPPFRMAGAGMESIVILDDDDEEAASTSASCSQATAQHLKTPVK---SQPVPAPTHITQSPFASA---------------------------------------KKDTHVLKVENEKLFNEFVEHCSKHSQEHPEVMTYLQTRYSKALPTFLTSVEFRNTLGRCLTRAQANAGKTFVYINELCTVLKQHTPRKRSSIQSLSVKAKPEEKSNGVNVKEDTQGEQDGGKDVKQQEEESKKTKRASRRQIAYLENLLKVYNEEIRRLQEGDLSLD--------------------------------------------DLEKEDSSYIQEHKLKRKMMKIYEKLCELKGCNTLTGRVIEQKIPYSGTRYPEINKKVER-------------FINSSEALLNPPDYS--DILKIVQRANERYNLQLSRKQQAQISQEAFRETGNKLQERRHLDMVY-NFGSHLTDPYKPTLDPALMDPALHRKLRSNRDVAISSLEEVINKYANKQEDMEVEE------TKKRQDRERLKKEAVNGQQSESKEK------------------EKEEQEEKEKEDEE-------EEEEDEEEDDSSDPDIEDEIQASEQQAGPEDDEEDVE-----------------------------EEPANISDNDQPINESSPLSIKSS-VQDTEEDEEQSPLSSTHEGSAETNTNTNGPAKQSLESTEIKPES-------IKPESIKPES------IKPETIKPESIKPENTDSLAEVKTEQVSSNHVEAVSASTETVSIVSEESSTAVTRSANCSPLLPTSPLLIDETGNYRKRKRRSTENHTSAHNGN-----CTEDSDIPLDMG--------VICCSEQEDLTCLKTPPRKTARNSQATPPPKKNKVNVATQCDPEEVIVLSDSE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VMD0-1", "uniprot_id": "DAXX_DROME", "id": "Q9VMD0-1", "name": "Daxx-like protein", "aln": "MSASVICVDLSSESDEESPAKRRRLEDPLRLLTPSGRQSFPAKLLNIPKASLGSAMVVPVAETGPARETPVIVDPLRSMHIPSGITITKHQKNVLATNGNMNLSLAESNNNNNTTSLNKNVTPKQINVGTGQKVAWSVSSKAPSPNAVITTVPSHQVRVTPFNPIRLAPGSKIIPASNAMPAKIQPILGMGQPQQQAQAQQPKAIIVGFPKPNTAVAQMAQHQKPLTLQIHQKLIAGQQQHIASISQLQQVSLQQQQPLRPVSIQLQQQQNQRNGSLPGKQQKPLECPVPAQQEKLPRGP-LPTKPAEPLSGPLPTEPDEPLGGPLPTRPKPPVRSLQQPVNKNTAIGVQIQQSQEPLGGTLPTRQKPLGGQLLTQQKPPVGSIQQSVKQNTGIGVQIQQIPKVVVGQQPQKVYLNKLQQEQQKIFLGHLQQQQQKTFLGQLQQEQQKILGQLQQQKQQQQQQQKKILGQSQQQKVPLGQPQPQQKLPQQLNNSLVQLQQQHQQRTSVGQLQQQQPHQSQQKNSMVHVKQQPQQQKKISVGQFQQQPQQQQKTSVAQLQQQPQQQQKISVGQLQQQSQQQQKPSVGQLQQQSQQQQTPLVGQLQRQTQQQQKTSAGQFQQQPQQQQKISAGQLQEHSQQQQKTLAGQLQQQAQQQLNTSAGQLQQQQKPPKASLAQQAAAQKQGAGLGQQQQFQSQPQQRTSAGLLQQQQMPQKKIVMQPQLPKTSVVLPRPQQLPKNPLLVAQQQSPKTPLVNSVMGPQFPSQQPSLPVVNQITHKSMTIQRLPMLQTVQKILPKQIAPQQTPPPAHIVQKQTMPNAAMQNPPFAHRPPIVRPMTVAKISPVPTNNKVCIPMKPQMASYVSPTDPTMTAARTLPFRSSQRKTSEAPMTSTHVQGFTASATPPQRLLATPPHCAAALNEPLLLNLPPTTSITPQLTPTTTPPPAGPSAAVQQQQLAKAAAIKLNSLPEASISPVNRSPTASAKRIQPITVLKKSDEEWQRHLEQQQQKKHVQLQSSSMTTIVLVESPPTTPPTDKPEPERGPMTVEKSSIKPMATDKQSRAIKRPAVMISTKKSGLVVTEIVDLDEIPDIPPEKRGKECFPPIKNAAKAAPSVNAPFTTEYAALLRLCREVDKSTHMERLVKGELTQYYYSAPESFVMSCGFRNLVTMAMARIRSESYLVYVHLKYVLDELASRRLTKMFPTVRAIPPASQFPLPPASQFPLPPTLTTPKQPAIVKAPGQQTVMAGREQDDEVEEVTLVNVGTVSCEERRRDERIRHFYRTLHAITKRIKMLEEAEVDLNDEDSSYLQLERFKKRACQIYEKICDLKGESKSVRRQLKKPIHFKDSDYPHFNNSLSAFVNRMQDFPDYHDVLQILEKCNKEKELGLAKYEMKRIAYDAFNKVGRMLQSRRKNDLYETVTHYTANGKDPASSDPELLAKLKENNKKQTKISDILEKYALEQDLNAEERQEARLKEKKLKQVKADEEAAKLAALAEDDDKPCTSAQAAAKAAALAALKRGPAARGNVIRKKRAANGRIFKIADDGDDSEEESDSEDDDVEEFVNNFQANSDVSDADSEVEAVTSPKRDALPLAEEEDVIDITRDETGKKNDEGTPNGRLKIMSVSSLNANFVHGQDLHRKPNPMPSAKPVIADQIIISDEES", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .: : :.:: : . .: .: . ... : :: . : : : :: * : . : . . .: . . * : : : : ::: . : *: . . * . * . . . : .: : *:: : ::*: : *. : :. : :*::: ::: : : .:: *:: ::: * : ::: :: :... . *: .::: :: * .: ::* :*: . : * ::: .: :* : : :. : :* ::: .: . :: . *:. : :: : : . . . . : ::: :.: . . : : . .::: . : :: ::. : * . . . .: . :. : :. :. ::: . : . . . . :. . : : .: : .. .. . :. . : . . . :. . *.: :* :: **.: ", "identical_positions": 25, "similar_positions": 218, "identity": "1.51%" }, { "cls_id": "homologset.agr.MGI:1197019", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88758-1", "uniprot_id": "KCNS1_RAT", "id": "O88758-1", "name": "Delayed-rectifier potassium channel regulatory subunit KCNS1", "aln": "-------------------------------MVSEFPGPGSRVPWRPRDEALRVNVGGVRRLLSARALARFPGTRLGRLQAAVSEEQARRLCDDYDAAAREFYFDRHPGFFLGLLHFYRTGHLHVLDELCVFAFGQEADYWGLGENALATCCRARYLERRVTRPR-AWDEDSDAPSSVDPCPDEISDVQRELARYGAARCGRLRRRLWLTMENPGYSLPSKLFSCVSIGVVLASIAAMCIHSLPEYQAREAAAAVAAVAAGRSAEDVRDDPVLRRLEYFCIAWFSFEVSSRLLLAPSTRNFFCHPLNLIDIVSVLPFYLTLLAGAALGDRRGASGEELGDLGKVVQVFRLMRIFRVLKLARHSTGLRSLGATLKHSYREVGILLLYLAVGVSVFSGVAYTAE-EKNVGFDTIPACWWWGTVSMTTVGYGDVVPETVAGKLAASGCILGGILVVALPITIIFNKFSHFYRRQKALEAAVRSSGQREFEDLLSSVDGVSDVS-LETSRETSQEGRSTDLETQAP--SEPAKSHSY------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35173-1", "uniprot_id": "KCNS1_MOUSE", "id": "O35173-1", "name": "Delayed-rectifier potassium channel regulatory subunit KCNS1", "aln": "-------------------------------MVSEFPGPGSRVPWRPRDEALRVNVGGVRRLLSARALARFPGTRLGRLQAAASEEQARRLCDDYDAAAHEFYFDRHPGFFLGLLHFYRTGHLHVLDELCVFAFGQEADYWGLGENALATCCRARYLERRVARPR-AWDEDSDAPSSVDPCPDEISDVQRELARYGAARCGRLRRRLWLTMENPGYSLPSKLFSCVSIGVVLASIAAMCIHSLPEYQAREAAAAVAAVAAGRSAEEVRDDPVLRRLEYFCIAWFSFEVSSRLLLAPSTRNFFCHPLNLIDIVSVLPFYLTLLAGAALGDQRGASGEELGDLGKVVQVFRLMRIFRVLKLARHSTGLRSLGATLKHSYREVGILLLYLAVGVSVFSGVAYTAE-EENEGFHTIPACWWWGTVSMTTVGYGDVVPETVGGKLAASGCILGGILVVALPITIIFNKFSHFYRRQKALEAAVRSSGQREFEDLLSSVDGVSDVS-LETSRDTSQEGRSTDLETQAP--REPAKSHSY------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96KK3-1", "uniprot_id": "KCNS1_HUMAN", "id": "Q96KK3-1", "name": "Delayed-rectifier potassium channel regulatory subunit KCNS1", "aln": "MLMLLVRGTHYENLRSKVVLPTPLGGRSTETFVSEFPGPDTGIRWRRSDEALRVNVGGVRRQLSARALARFPGTRLGRLQAAASEEQARRLCDDYDEAAREFYFDRHPGFFLSLLHFYRTGHLHVLDELCVFAFGQEADYWGLGENALAACCRARYLERRLTQPH-AWDEDSDTPSSVDPCPDEISDVQRELARYGAARCGRLRRRLWLTMENPGYSLPSKLFSCVSISVVLASIAAMCIHSLPEYQAREAAAAVAAVAAGRSPEGVRDDPVLRRLEYFCIAWFSFEVSSRLLLAPSTRNFFCHPLNLIDIVSVLPFYLTLLAGVALGDQ---GGKEFGHLGKVVQVFRLMRIFRVLKLARHSTGLRSLGATLKHSYREVGILLLYLAVGVSVFSGVAYTAEKEEDVGFNTIPACWWWGTVSMTTVGYGDVVPVTVAGKLAASGCILGGILVVALPITIIFNKFSHFYRRQKALEAAVRNSNHQEFEDLLSSIDGVSEAS-LETSRETSQEGQSADLESQAP--SEPPHPQMY------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6Z6V7-1", "uniprot_id": "A0A8M6Z6V7_DANRE", "id": "A0A8M6Z6V7-1", "name": "Delayed-rectifier potassium channel regulatory subunit KCNS1", "aln": "-------------------------------MVKEK---NAWWILDPKDHLLHINVGGLRNTLCSSILKKFPDTRLGQLLSCDSEDDILQLCDDFDVQRKEFYFDRNPGLFPYVLHFYQTGKLHIMEELCIFSFSQEIEYWGISDFFLDSCCSYRYLDRKLERHHKSWDEESDV-SSVDTSVDEISDLNKDIEHFHEMRFGNIRKCLWLTLENPGYSIPSKLFSLLSICVVLISIATMCINSIPEYQKFDENG------------NLIEDPTMHVLEVFCICWFTFEVVTRMLLAPNHRKFFLLPLNVIDIISVMPIYITIFFDMLIGSE-----SELGNLGKLVQVLRLMRIFRVLKLARHSTGLRSLGATLRHSYREVGILLLYLAVGVSVFSGMAYTAENEEDVGLDTIPACWWWGTVSMTTVGYGDVVPVTVAGKLAASGCILGGTLVVALPITIIFNKFSHFYRKQKALEASVRNNNNKKFVMRQQRNSGDSAIHGHIHCLEDEEMDEDVDFDTGVVNFCYEDHPLTYTVRCVH", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*.* .: *. *::****:*. *.: * :**.****:* :. **:: :****:* :******:**:* :****:**:**:::***:*:*.** :***:.: * :** ***:*:: : : :***:**. ****.. *****::::: :: * *.:*: ****:******:****** :** *** ***:***:*:**** : . : :**.:: ** ***.**:*** :*:****. *:** ***:***:**:*:*:*:: . :*.. .*:*.***:***:*************************:**********************:***** *:: *:.*********************** **.************ *******************:******:**...:::* . .* * . : .: ....*::: . :. * ", "identical_positions": 271, "similar_positions": 123, "identity": "50.28%" }, { "cls_id": "homologset.agr.MGI:1197020", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O14905-1", "uniprot_id": "WNT9B_HUMAN", "id": "O14905-1", "name": "Protein Wnt-9b", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------MRPPPALALAGLCLLALP--AAAASYFGLTGREVLTPFPGLGTAAAP--------------------------------AQGGAHLKQCDLLKLSRRQKQLCRREPGLAETLRDAAHLGLLECQFQFRHERWNCSLEGR--MGLLKRGFKETAFLYAVSSAALTHTLARACSAGRMERCTCDDSPGLESRQAWQWGVCGDNLKYSTKFLSNFLGSKRGNKDLRARADAHNTHVGIKAVKSGLRTTCKCHGVSGSCAVRTCWKQLSPFRETGQVLKLRYDSAVKVSSATNEALGRLELWAPARQGSLTKGLAPRSGDLVYMEDSPSFCRPSKYSPGTAGRVCSREASCSSLCCGRGYDTQSRLVAFSCHCQ----------------------------------------------------------------------VQWCCYVECQQCVQEELVYTCKH--------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O35468-1", "uniprot_id": "WNT9B_MOUSE", "id": "O35468-1", "name": "Protein Wnt-9b", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------MRPAPALALAALCLLVLPAAAAAAAYFGLTGREVLTPFPGLGTAAAP--------------------------------AQAGAHLKQCDLLKLSRRQKQLCRREPGLAETLRDAAHLGLLECQFQFRQERWNCSLEGR--TGLLQRGFKETAFLYAVSAAALTHALARACSAGRMERCTCDDSPGLESRQAWQWGVCGDNLKYSTKFLSNFLGPKRGSKDLRARADAHNTHVGIKAVKSGLRTTCKCHGVSGSCAVRTCWKQLSPFRETGQVLKLRYDTAVKVSSATNEALGRLELWAPAKPGGPAKGLAPRPGDLVYMEDSPSFCRPSKYSPGTAGRVCSRDSSCSSLCCGRGYDTQSRMVVFSCHCQ----------------------------------------------------------------------VQWCCYVECQQCAQQELVYTCKR--------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LQL8-1", "uniprot_id": "A0ABK0LQL8_RAT", "id": "A0ABK0LQL8-1", "name": "Protein Wnt", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------MR-----------LWDSP--------CCLTGREVLTPFPGPGTAAAP--------------------------------AQAGAHLKQCDLLKLSRWQKQLCRREPGLAETLRDAAHLGLLECQFQFRQERWNCSLEGR--TGLLQRGFKETAFLYAVSAAALTHALARACSAGRMERCTCDDSPGLESRQAWQWGVCGDNLKYSTKFLSNFLGPKRGSKDLRARADAHNTHVGIKAVKSGLRTTCKCHGVSGSCAVRTCWKQLSPFRETGQVLKLRYDTAVKVSSATNEALGRLELWVPAKPGGPAKGLAPRPVDLVYMEDSPSFCRPSKYSPGTAGRVCSRDTSCSSLCCGRGYDTQSRMVAFSCHCQGSMRMLGRSLMTEGPRRNHSDPRPFSGMTLLTKETHPQLVRRQKQIENCFPLKEDVFLGNPRRPSPLGPLILFCFEGTRQEGSLGELGNSNTQIYDLYPDSMARRARGEGGSKMNLKLRLRLTDH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P40589-1", "uniprot_id": "WNT4_DROME", "id": "P40589-1", "name": "Protein Wnt-4", "aln": "MPSPTGVFVLMILTHLSFGLGQVRNEDQLLMVGQNGDLDSSNPAIHHQQHQQHQQHQQHQQHQSNHNLNNGNMNSTILNTLMGNNAGQVVNSSPGGGGSMINQLGSSTSSVPSVIGGGVGSVGNPWHSAVGLGVPGNGMGLPSSHGLGGNMGSHPHGHALAGLAKLGIIVPGGQGLPGNLGYGGTMLNGGGVGGAAGMGLGIGSNTNNMDMQQGLYNEHFISEHTVMAVFTSQGQVGGPCRYMPATRRQNHQCRKETGLPGTLSEARRLATTHCEEQFRYDRWNCSIETRGKRNIFKKLYKETAFVHALTAAAMTHSIARACAEGRMTKCSCGPKKHNREAQDFQWGGCNDNLKHGKRVTRSFLDLRGGDGDEVSEILRHDSEVGIEAVSSQMMDKCKCHGVSGSCSMKTCWKKMADFNATATLLRQKYNEAIRKAPNQRSMRQVSSSRMKKPKQRRKKPQQSQYTTLYYLETSPSYCAVTKD------RQCLHPDNCGTLCCGRGYTTQVVKQVEKCRCRFN--------------------------------------------------------------------NGRCCQLICDYCQRLENKYFCK---------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .: * * **. :. * * : :* *:: **:*.**. ** :* :*. .*: *** :*****:* * .:::: :*****::*:::**:**::****: *** :*:*. . .. * :*** *.****:..:. .**. : *. * :. *::.***:**.* : .**********:::****::: *. *. :*: :*: *:: :. .. . * .: * *:* ***:* :* * * : .*.:******* ** . .*:*: * : * . ", "identical_positions": 112, "similar_positions": 94, "identity": "17.34%" }, { "cls_id": "homologset.agr.MGI:1197514", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4ABZ5-1", "uniprot_id": "D4ABZ5_RAT", "id": "D4ABZ5-1", "name": "DNA polymerase epsilon subunit", "aln": "-----------MAPERLRSRTVSAFK-LRGLLLRSEATKYLTEALQS------------------VTELELEENLEKIIDAVEKQPLSSNMIERSVVEAAVQECSQSVDETI------------------------------------------------------EHIFNIIGAFDIPHFIYNSERKKFLPLSMTNH----AAPTIFGTARDKAELYRERYTILHQRTHRHELFTPPVIGS---------------HPDESGSKFQLKTIETLLGSTSKVGDVIVLGMITQLKEGKFFLEDPTGTVQLDLSKAQFHSG-LYTEACFVLAEGCFEDQ--VFHANAFGFPPTEPSSTTRAYYGNINFFGGP--------SNASVKASAKLRQLEEENKDAMFVIV-SDVWLDQVQVLEKLHVMFSGYSPAPPTCFILCGNFSSAPYGKNQVQ-------ALKDSLKSLADIICEYPSIHQSSRFVFVPGPE-------DPGFGSILPRPPLAESITQEFRQRVPFSVFTTNPCRIQYCTQEIIIFREDLVNKMCRNCVRFPSS----------------------------------SLDIPTHFVKTVLSQGHLAPLPLYVSPVYWAYDYTLRVYPVPDLLVIADKYDP-FTVTNTECLCINPGSFPRSG-FAFKVFYPSSKTVEDSKLQGF--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O54956-1", "uniprot_id": "DPOE2_MOUSE", "id": "O54956-1", "name": "DNA polymerase epsilon subunit 2", "aln": "-----------MAPERLRSRTVSAFK-LRGLLLRSEATKYLTEALQS------------------VTELELEENLGKIIDAVEKQPLSSNMIERSVVEAAVQECSQSMDETI------------------------------------------------------EHVFNIIGAFDIPRFIYNSERKKFLPLSMTNH----AAPTLFGTARDKAELYLERYTILHQRTHRHELFTPPVIGS---------------HLEESGSKFQLKTIETLLGSTSKVGDVIVLGMITQLKEGKFFLEDPTGTVQLDLSKAQFHSG-LYTEACFVLAEGWFEDQ--VFHANAFGFPPTEPSSTTRAYYGNINFFGGP--------SNASVKTYTKLRQLEDENKDAMFVIV-SDVWLDQVQVLEKFHVMFSGYSPAPPTCFILCGNFSSAPYGKNQVQ-------ALKDSLKSLADIICEYPSIHQSSRFVFVPGPE-------DPGFGSILPRPPLAESITQEFRQRVPFSVFTTNPCRIQYCTQEIIIFREDLVNKMCRNCVRFPSS----------------------------------SLDIPTHFVKTILSQGHLAPLPLYVCPVHWAYDYTLRVYPVPDLLVIADKYDP-FTVTNTDCLCINPGSFPRSG-FAFKVFYPSSKTVEDSKLQGF--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P56282-1", "uniprot_id": "DPOE2_HUMAN", "id": "P56282-1", "name": "DNA polymerase epsilon subunit 2", "aln": "-----------MAPERLRSRALSAFK-LRGLLLRGEAIKYLTEALQS------------------ISELELEDKLEKIINAVEKQPLSSNMIERSVVEAAVQECSQSVDETI------------------------------------------------------EHVFNIIGAFDIPRFVYNSERKKFLPLLMTNH----PAPNLFGTPRDKAEMFRERYTILHQRTHRHELFTPPVIGS---------------HPDESGSKFQLKTIETLLGSTTKIGDAIVLGMITQLKEGKFFLEDPTGTVQLDLSKAQFHSG-LYTEACFVLAEGWFEDQ--VFHVNAFGFPPTEPSSTTRAYYGNINFFGGP--------SNTSVKTSAKLKQLEEENKDAMFVFL-SDVWLDQVEVLEKLRIMFAGYSPAPPTCFILCGNFSSAPYGKNQVQ-------ALKDSLKTLADIICEYPDIHQSSRFVFVPGPE-------DPGFGSILPRPPLAESITNEFRQRVPFSVFTTNPCRIQYCTQEITVFREDLVNKMCRNCVRFPSS----------------------------------NLAIPNHFVKTILSQGHLTPLPLYVCPVYWAYDYALRVYPVPDLLVIADKYDP-FTTTNTECLCINPGSFPRSG-FSFKVFYPSNKTVEDSKLQGF--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VRQ7-1", "uniprot_id": "DPOE2_DROME", "id": "Q9VRQ7-1", "name": "DNA polymerase epsilon subunit 2", "aln": "---------MDVDLLPLRKRITNTFK-LCGFLIRSENSSYLAEQLLP------------------FDAAERDKWLTVITENLQSQKLLTPHVERAALEKAINELNRVGLDEG------------------------------------------------------ETVFALIDAFTVPRFRYNQRIKKFELDTQP--------RQLLTAPRMKSDYMQQRYAMLLQKTLRHDLFAPAVIQDGV-------------GAEAQAKKFKLQFAENLL-ATSAMKEAVVLGLLTQLKEGKFYVEDPTGCVQLDLTGARFHAG-FFCEGCFVLAEGNYNNG--VLKVDGLGFPPAEPANSSRAFFGTANTWGGE--------SAKLLKYSAGLQELERTNTETTIVFL-SDVRLDLPVVMEKLRQLFVGYDSCPPQAIVLMGPFTAS---TRNHH-------ELRHHLDALGGLAAGCEQLKKQTDLILVPSSE-------DPTAPNILPRAPIPECLAAGLLKAWPRTQLATNPCRLQYCTQQIVVCRLDLMAKFCRNTLHFPED----------------------------------TSQIEQHFARTIVCQGHLVPIHPIAMPVHWDYDPALWLYPLPDLIVMGDSCQS-FSSSQHGCTVLNTGSFVKSK-FAFKVYIPATRTIEDSEIPDELE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P24482-1", "uniprot_id": "DPB2_YEAST", "id": "P24482-1", "name": "DNA polymerase epsilon subunit B", "aln": "MFGSGNVLPVKIQPPLLRPLAYRVLSRKYGLSIKSDGLSALAEFVGTNIGANWRQGPATIKFLEQFAAVWKQQERGLFIDQSGVKEVIQEMKEREKVEWSHEHPIQHEENILGRTDDDENNSDDEMPIAADSSLQNVSLSSPMRQPTERDEYKQPFKPESSKALDWRDYFKVINASQQQRFSYNPHKMQFIFVPNKKQNGLGGIAGFLPDIEDKVQMFLTRYYLTNDRVMRNENFQNSDMFNPLSSMVSLQNELSNTNRQQQSSSMSITPIKNLLGRDAQN--FLLLGLLNKNFKGNWSLEDPSGSVEIDISQTIPTQGHYYVPGCMVLVEGIYYSVGNKFHVTSMTLPPGERREITLETIGNLDLLGIHGISNNNFIARLDKDLKIRLHLLEKELTDHKFVILGANLFLDDLKIMTALSKILQKLNDDPPTLLIWQGSFTSVPVFASMSSRNISSSTQFKNNFDALATLLSRFDNLTENTTMIFIPGPNDLWGSMVSLGASGTLPQDPIPSAFTKKINKVCKNVVWSSNPTRIAYLSQEIVIFRDDLSGRFKRHRLEFPFNESEDVYTENDNMMSKDTDIVPIDELVKEPDQLPQKVQETRKLVKTILDQGHLSPFLDSLRPISWDLDHTLTLCPIPSTMVLCDTTSAQFDLTYNGCKVINPGSFIHNRRARYMEYVPSSKKTIQEEIYI---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ** .:. *: ::.: . *:* : . . :. : : : : ** :* : :. : : . * :*.* :* ** . :* :: . * : ** : ::. *:: * . : . : ....:.: :.** : ::**::.: :*:: :***:* *::*:: : * : .*:**.** : . ::. .: :** * . : *. : * : . *: ** .: :*:: ::: ** :: : :: . ** :: * *:: ::. :.:*. : . .: :.: ::::*..: . . **: *:...:: : : ::** *: * :*:* : * ** :: *: :.** . . ::.:*:: **** *: *: * * :* : *:*. :*: *. .. * : * :*.*** :. : : *:.:. :.:: ", "identical_positions": 90, "similar_positions": 186, "identity": "12.97%" }, { "cls_id": "homologset.agr.MGI:1197515", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A9L1-1", "uniprot_id": "D4A9L1_RAT", "id": "D4A9L1-1", "name": "", "aln": "MSFPQLGYPQYLSAAGPGAYGGERPGMLAAAAAAAAAASSGRPGTAELGAGAGAAAVTSVLGMYAAAGPYAGAPNYSAFLPY-AADLSLFSQMGSQYELKDNPGVHPATFAAHTTPAYYPYGQFQYGDPGRPKNATRESTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKVTWGARSKDQEDGALFGSDTEGDPEKAEDDEEIDLESIDIDQIDERDGDQSNEDEEDKVEAPRARVAPPAPARDQSSPLSAAETLKSQDSPLGLAKEVSEPGSTRLLSPGAAAVGLQGAPHSKPKIWSLAETATSPDGAPKASPPPPSSHASAHGPPSGSPLQHPAFLPSHGLYTCHIGKFSNWTNGAFLAQGSLLNMRSFLGVSAPHAAPHGPHVTAPPPPQLPVQVATGVLHGEKASASSSPALPERDLVTRPDSPPQQLKSPFQPVRDNSLAPQEGTPRILAALSSA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P81068-1", "uniprot_id": "IRX1_MOUSE", "id": "P81068-1", "name": "Iroquois-class homeodomain protein IRX-1", "aln": "MSFPQLGYPQYLSAAGPGAYGGERPGVLAAAAAAAAAASSGRPGTAELGAGAGAAAVTSVLGMYAAAGPYAGAPNYSAFLPY-AADLSLFSQMGSQYELKDNPGVHPATFAAHTTPAYYPYGQFQYGDPGRPKNATRESTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKVTWGARSKDQEDGALFGSDTEGDPEKAEDDEEIDLESIDIDQIDERDGDQSNEDEEDKAEAPRARVAPPASARDQSSPLSAAETLKSQDSPLGLVKEVSEPGSTRLLSPGAAAVGLQGAPHSKPKIWSLAETATSPDGAPKASPPPPSSHASAHGPPSGSPLQHPAFLPSHGLYTCHIGKFSNWTNGAFLAQGSLLNMRSFLGVSAPHAAPHGPHLTAPPPPQPPVQVATGVLHGEKASARSSPALPERDLVTRPDSPPQQLKSPFQPVRDNSLAPQEGTPRILAALPSA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P78414-1", "uniprot_id": "IRX1_HUMAN", "id": "P78414-1", "name": "Iroquois-class homeodomain protein IRX-1", "aln": "MSFPQLGYPQYLSAAGPGAYGGERPGVLAAAAAAAAAASSGRPGAAELGGGAGAAAVTSVLGMYAAAGPYAGAPNYSAFLPY-AADLSLFSQMGSQYELKDNPGVHPATFAAHTAPAYYPYGQFQYGDPGRPKNATRESTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKVTWGARSKDQEDGALFGSDTEGDPEKAEDDEEIDLESIDIDKIDEHDGDQSNEDDEDKAEAPHAPAAPSALARDQGSPLAAADVLKPQDSPLGLAKEAPEPGSTRLLSPGAAAGGLQGAPHGKPKIWSLAETATSPDGAPKASPPPPAGHPGAHGPSAGAPLQHPAFLPSHGLYTCHIGKFSNWTNSAFLAQGSLLNMRSFLGVGAPHAAPHGPHLPAPPPPQPPVAIAPGALNGDKASVRSSPTLPERDLVPRPDSPAQQLKSPFQPVRDNSLAPQEGTPRILAALPSA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PF69-1", "uniprot_id": "A0A8M1PF69_DANRE", "id": "A0A8M1PF69-1", "name": "", "aln": "MSFPQLGYPQYLSAS-QAVYGGDRPGVLTPSSRAGSAEIGG-------SASAAAAAVSSVLGMY----PYA--HNYSAFLPYTSADLALFSQMGSQYDLKDSPGVHPASFAAHTSPAFYPYGQFQYGDPARPKNATRESTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKVTWGARSKDDEN--IFGSDNEGDAEKNEDEEEIDLESIDIDKIDDNDGDQSNEEDEDKRAELESLQEKRHASKEPSD---------------------GNNNTTRVLSPGRQG-GFQVPVSNKPKIWSLAETATSPDSAQKPTSP-------------SVPVSHPAFLPSHGLYTCQIGKFHNWTNGAFLGQNSLLNVRSFLGVN-QHNHPAQQQQQQTGPASLQVLSAG---NTDKMPEDLSPKHIDRENVLRNESPTQPLKSSFRPLHDSPRNQQESTQRVLTALSSA", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**************: ..***:***:*:.:: *.:* .* ...*.****:****** *** ******** :***:*********:***.******:*****:**:***********.**********************************************************************:*: :****.***.** **:***********:**:.*******::*** .: ::: .. : .:**:**** . *:* . .***************.* *.:.* . *:.*************:**** ****.***.*.****:******. * * : . *.. * * : :* . ** :*: * * :**.* ***.*:*::*.. **.* *:*:**.**", "identical_positions": 281, "similar_positions": 85, "identity": "58.42%" }, { "cls_id": "homologset.agr.MGI:1197517", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P53670-1", "uniprot_id": "LIMK2_RAT", "id": "P53670-1", "name": "LIM domain kinase 2", "aln": "---------------------MAALAGEEAWRCRGCGNYVPLS--QRLYRTANEAWHSSCFRCSECQESLTNWYYEKDGKLYCHKDYWAKFGEFCHGCSLLMTGPAMVAGEFKYHPECFACMSCKVIIEDGDAYALVQHATLYCGKCHNEVVLAPMFERLSTESVQDQLPYSVTLISMP-ATTECRRGFSVSVESASSN------------YATTVQVKEVNRMHISPNNRNAIHPGDRILEINGTPVRTLRVEEVEDAINQTSQTLQLLIEHDPVPQRLDQLRLDTRLSPHMQSSGHTLMLSTLDAKENQEGTLRR--------RSLRRSNSISKSPGPSSPKEPLLLSR----------------------------DISRSESLRCSSSYSQQIFRPCDLIHGEVLGKGFFGQAIKVTHKATGKVMVMKELIRCDEETQKTFLTEVKVMRSLDHPNVLKFIGVLYKDKKLNLLTEYIEGGTLKDFLRN-VDPFPWQQKVRFAKGIASGMAYLHSMCIIHRDLNSHNCLIKLDKTVVVADFGLSRLIVEERK------------RPPVEKAATKKRTLRKS---DRKKRYTVVGNPYWMAPEMLNGKSYDETVDVFSFGIVLCEIIGQVYADPDCLPRTLDFGLNVKLFWEKFVPTDCPPAFFPLAAICCKLEPESRPAFSKLEDSFEALSLFLGELAIPLPAELEELD----HTVSMEYGLTRDSPP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O54785-1", "uniprot_id": "LIMK2_MOUSE", "id": "O54785-1", "name": "LIM domain kinase 2", "aln": "---------------------MAALAGDEAWRCRGCGTYVPLS--QRLYRTANEAWHGSCFRCSECQESLTNWYYEKDGKLYCHKDYWAKFGEFCHGCSLLMTGPAMVAGEFKYHPECFACMSCKVIIEDGDAYALVQHATLYCGKCHNEVVLAPMFERLSTESVQDQLPYSVTLISMP-ATTECRRGFSVTVESASSN------------YATTVQVKEVNRMHISPNNRNAIHPGDRILEINGTPVRTLRVEEVEDAIKQTSQTLQLLIEHDPVPQRLDQLRLDARLPPHMQSTGHTLMLSTLDTKENQEGTLRR--------RSLRRSNSISKSPGPSSPKEPLLLSR----------------------------DISRSESLRCSSSYSQQIFRPCDLIHGEVLGKGFFGQAIKVTHKATGKVMVMKELIRCDEETQKTFLTEVKVMRSLDHPNVLKFIGVLYKDKKLNLLTEYIEGGTLKDFLRS-VDPFPWQQKVRFAKGISSGMAYLHSMCIIHRDLNSHNCLIKLDKTVVVADFGLSRLIVEERK------------RPPVEKATTKKRTLRKS---DRKKRYTVVGNPYWMAPEMLNGKSYDETVDVFSFGIVLCEIIGQVYADPDCLPRTLDFGLNVKLFWEKFVPTDCPPAFFPLAAICCKLEPESRPAFSKLEDSFEALSLFLGELAIPLPAELEDLD----HTVSMEYGLTRDSPP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P53671-1", "uniprot_id": "LIMK2_HUMAN", "id": "P53671-1", "name": "LIM domain kinase 2", "aln": "---------------------MSALAGEDVWRCPGCGDHIAPS--QIWYRTVNETWHGSCFRCSECQDSLTNWYYEKDGKLYCPKDYWGKFGEFCHGCSLLMTGPFMVAGEFKYHPECFACMSCKVIIEDGDAYALVQHATLYCGKCHNEVVLAPMFERLSTESVQEQLPYSVTLISMP-ATTEGRRGFSVSVESACSN------------YATTVQVKEVNRMHISPNNRNAIHPGDRILEINGTPVRTLRVEEVEDAISQTSQTLQLLIEHDPVSQRLDQLRLEARLAPHMQNAGHPHALSTLDTKENLEGTLRR--------RSLRRSNSISKSPGPSSPKEPLLFSR----------------------------DISRSESLRCSSSYSQQIFRPCDLIHGEVLGKGFFGQAIKVTHKATGKVMVMKELIRCDEETQKTFLTEVKVMRSLDHPNVLKFIGVLYKDKKLNLLTEYIEGGTLKDFLRS-MDPFPWQQKVRFAKGIASGMAYLHSMCIIHRDLNSHNCLIKLDKTVVVADFGLSRLIVEERK------------RAPMEKATTKKRTLRKN---DRKKRYTVVGNPYWMAPEMLNGKSYDETVDIFSFGIVLCEIIGQVYADPDCLPRTLDFGLNVKLFWEKFVPTDCPPAFFPLAAICCRLEPESRPAFSKLEDSFEALSLYLGELGIPLPAELEELD----HTVSMQYGLTRDSPP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8IR79-1", "uniprot_id": "LIMK1_DROME", "id": "Q8IR79-1", "name": "LIM domain kinase 1", "aln": "MHHQQRLRANGGRGGTGLGAGSGPVSGGHSPLCAHCRGQLLPHPEEPIVMALGQQWHCDCFRCSVCEGHLHNWYFEREGLLYCREDYYGRFGDACQQCMAVITGPVMVAGEHKFHPECFCCTACGSFIGEGESYALVERSKLYCGQCYGKRSCQPADAKARITTAGKPM-HSIRLVEIPKDATPGLRVDGVALDDGCPTVRITDLFCNFFLWLTSMAEQCCGAPYRIDVNLTNLHIGDRILEVNGTPVSDSSVEQIDKLIRSNEKMLQLTVEHDPVQVCRSCSQADIQRAMSASTLILPLSTSASSVEVGRERLYKTPGEQGTKARKLRQATNASTTIPPAAGATAMTQLKEKERCSSLSKLLDEQHQAQQHSAHPQLYDLSRTQSCRVVQ-KPQRIFRATDLVIGEKLGEGFFGKVFKVTHRQSGEVMVLKELHRADEEAQRNFIKEVAVLRLLDHRHVLKFIGVLYKDKKLHMVTEYVAGGCLKELIHDPAQVLPWPQRVRLARDIACGMSYLHSMNIIHRDLNSMNCLVREDRSVIVADFGLARSVDAPRLPSGNMTPGGYGSGANSDAPMSPSGTLRRSKSRQRRQRYTVVGNPYWMAPEMMKGLKYDEKVDVFSFGIMLCEIIGRVEADPDFMPRNSDFSLNQQEFREKFC-AQCPEPFVKVAFVCCDLNPDMRPCFETLHVWLQRLADDLAADRVPPERLLHEIETFQEWYASSEDALSPTSQRSLNNLDELVKSAVDSEISPVEKEKENMVIKPQDIPKSPHLGKDFSPSGERLRDSMRARRRQRFLGAQEERRNLTPDTESKERALKKALKKCRPFGERGYLVDLRAGAELQLEDVRDLNTYSDVDSSCDTSLNYHDVNNLPAAQEDENTVKPGKEELLEESTNKPSNQESQHHRLAIDDMRTRLNQCRSKFEHLEEASRRNFNQSQHSMKNFFKTPPVALKMFQRLEHEAAALNGGNNCPPPPPRTQRINQTPIFGRKNPPVAIVGQKLQHAESLEDLASSGVAKQLATPAPKRSKATATTKGGQSSNPPLFLPPSLNISVALNSNGNVTTTTNTNSSCPPSASDWLPKKHKLTLPLPSAQQQRTSSNHRLPMCNNKGKTLKPLPSRTGSQGIPASNCVSPTRSSRPGSPTKHLAQRHTAATAQRLTNAAATHQQQHQQQSSKTTRLNILSPEKVHRLGARLTDQKQKMREEAAATASSVGGAGCAAGTAAGSLNGHRTIGSSGTPNSAVGERRRRAAPSPPVRTHFNTRC", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ..::* . * * : : : .: ** .***** *: * ***:*::* *** :**:.:**: *: * ::*** *****.*:*****.* :* :* :*::****:::.****:*:.: * : :. . : :*: *:.:* :* * .*:::..... : *:: : . : * . :* ******:***** **:::. * ...: *** :***** . : : : . .. . *: ..: . * : *.**::.. *.: *:: .: : *:**::* * . .*:***. **: ** **:****:.:****: :*:***:*** *.***:*:.*:.** *:* *** :**************:::***: ** **::::. : :** *:**:*:.*:.**:***** ******** ***:: *::*:******:* : * . : . : . ***:. :*::***************::* .***.**:*****:******:* **** :**. **.** : * *** ::** .*. :* :** *:*: **.*..*. :: *: *. :* *.::: .* : .*: * ", "identical_positions": 261, "similar_positions": 198, "identity": "20.71%" }, { "cls_id": "homologset.agr.MGI:1197518", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0M0C0-1", "uniprot_id": "A0ABK0M0C0_RAT", "id": "A0ABK0M0C0-1", "name": "non-specific serine/threonine protein kinase", "aln": "---MPIALLALAMSSSFFNPSFAFSSHFDPDGAPLSELSWSSSLAVVAVSFSGIFTVIVLMLACLCCKKGGIGFKEFENAEGEEYVADFSEQGSPAATVQNGPDVYVLPLTEVSLPMAKQPGRSVQLLKSTDLGRHSLLYLKEIGHGWFGKVFLGEVHSGVSGTQVVVKELKASASVQEQMQFLEEAQPYRALQHSNLLQCLAQCAEVTPYLLVMEFCPLGDLKGYLRSCRVTESMAPDPLTLQRMACEVACGVLHLHRHNYVHSDLALRNCLLTADLTVKVGDYGLAHCKYREDYLVTADQLWVPLRWIAPELVDEVHGNLLVVDQTKTSNVWSLGVTIWELFELGAQPYPQHSDRQVLAYAVREQQLKLPKPQLQLTLSDRWYEVMQFCWLQPEQRPTAEEVHLLLSYLCAKGTTELEEEFERRWRSLRPGGSAGLGSASTVPAAAAS---ELTAASSFPLLEQFTS-DGFHVD-SDDVLTVTETSHGLNFEYKWEAGCGAEAYPPPGAAFSPGS-AGRLQELCAP----------------------DSSPPGVVPVLSAHSPSVGSEYFIRLEG-----------------AVPAAGHDPDCAG----CAPSPQ---AVSEQDNNSEESTAASLVMEPLLGHAPPTGGLWGPCDHHSRR--RQEPPCP-SRSPSPGTPMLP-----AEDIDWGVATFCPPFFDD-PLGTSPSGSPGAQPSPS--DEELEEGKTGRAAQCGHWSSN------------MSANNNSGS----------RDPESWDPGYVSSFTDSYRDDCSSLEQTPRAS--PELGHPLSQEDSRDFLPGLVAASPGQESSRCFN-LLPLCPAKGLAPAACLVPPPWTEAAVGGAENPIVEPKLAQEAEGSAEPQLPLPSVPSPSHE------------------GASLPSEEASAP---DIQPASPTPAAGSWVTVPEPAP------------TLDSSSSSLGQEVPSSE-----------------DEDTTEVTSGVFTDLSSDGPHTEKSGIVPALRCLQKQVGTPDSLDSLDIPSSASDGGCEVLSPSAAGPAGGQPRAMDSGYDTENYESPEFVLKEAHES--------SEPEAFGEPASEGESPGPDTLLSVS----LGDLSRKNPYRDSAYFSDLDAESEPNFGPEKHSGIQDSQKEQDLRSPPSPGHESVQAFPR---------------------------PEVS--------SEVLPPPQQSEEPMPE------GPGSEPLEAQGPVEVEPVPGPSHSKCLLLTSAPLSSEGNGT----ESRGPPGPLSGPAQTG----------------------RMGNP----------------------------STSR--SPLCLALPGHPGTSEGRP------EDDE-DTEDSEESDEELRCYSVQEPSEDSEEEPSAVPVVVAESQSARNLRSLLKMPSLLSEAFCDDLERKKKAVSFFDDVTVYLFDQESPTREAGEPFPSTKE-CPTFLEGSPGSPSATGVPLRAGHSPDSSAPEPGSRFEWDGDFPLVPG-----KAALVTALDPADPVLAAPPTPAAPFSRFTVSPAPPSRFSITQVSDSDAQSMGVSGPFGAQRTIYIYQSHCKVSLCTCSCQQNLGTRFPSTDSQPD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80YE4-1", "uniprot_id": "LMTK1_MOUSE", "id": "Q80YE4-1", "name": "Serine/threonine-protein kinase LMTK1", "aln": "------------MSSSFFNPSFAFSSHFDPDGAPLSELSWSSSLAVVAVSFSGIFTVVILMLACLCCKKGGIGFKEFENAEGDEYVADFSEQGSPAAAAQTGPDVYVLPLTEVSLPMAKQPGRSVQLLKSTDLGRHSLLYLKEIGHGWFGKVFLGEVHSGVSGTQVVVKELKVSASVQEQMQFLEEAQPYRALQHSNLLQCLAQCAEVTPYLLVMEFCPLGDLKGYLRSCRVTESMAPDPLTLQRMACEVACGVLHLHRHNYVHSDLALRNCLLTADLTVKVGDYGLSHCKYREDYLVTADQLWVPLRWIAPELVDEVHGNLLVVDQTKSSNVWSLGVTIWELFELGAQPYPQHSDRQVLAYAVREQQLKLPKPQLQLALSDRWYEVMQFCWLQPEQRPTAEEVHLLLSYLCAKGTTELEEEFERRWRSLRPGGSTGLGSGSAAPAAATAASAELTAASSFPLLERFTS-DGFHVD-SDDVLTVTETSHGLNFEYKWEAGCGAEEYPPSGAASSPGS-AARLQELCAP----------------------DSSPPGVVPVLSAHSPSVGSEYFIRLEG-----------------AVPAAGHDPDCAG----CAPSPQ---AVTDQDNNSEESTVASLAMEPLLGHAPPTEGLWGPCDHHSHR--RQGSPCP-SRSPSPGTPMLP-----AEDIDWGVATFCPPFFDD-PLGASPSGSPGAQPSPS--DEEPEEGKVGLAAQCGHWSSN------------MSANNNSAS----------RDPESWDPGYVSSFTDSYRDDCSSLEQTPRAS--PEVGHLLSQEDPRDFLPGLVAVSPGQEPSRPFN-LLPLCPAKGLAPAACLITSPWTEGAVGGAENPIVEPKLAQEAEGSAEPQLPLPSVPSPSCE------------------GASLPSEEASAP---DILPASPTPAAGSWVTVPEPAP------------TLESSGSSLGQEAPSSE-----------------DEDTTEATSGVFTDLSSDGPHTEKSGIVPALRSLQKQVGTPDSLDSLDIPSSASDGGCEVLSPSAAGPPGGQPRAVDSGYDTENYESPEFVLKEAHES--------SEPEAFGEPASEGESPGPDPLLSVS----LGGLSKKSPYRDSAYFSDLDAESEPTFGPEKHSGIQDSQKEQDLRSPPSPGHQSVQAFPR---------------------------SAVS--------SEVLSPPQQSEEPLPE------VPRPEPLGAQGPVGVQPVPGPSHSKCFPLTSVPLISEGSGT----EPQGPSGQLSGRAQQG----------------------QMGNP----------------------------STPR--SPLCLALPGHPGALEGRP------EEDE-DTEDSEESDEELRCYSVQEPSEDSEEEPPAVPVVVAESQSARNLRSLLKMPSLLSEAFCDDLERKKKAVSFFDDVTVYLFDQESPTRETGEPFPSTKESLPTFLEGGPSSPSATGLPLRAGHSPDSSAPEPGSRFEWDGDFPLVPG-----KAALVTELDPADPVLAAPPTPAAPFSRFTVSPTPASRFSITHISDSDAQSVGGP-------------------------AAGAGGRYTEA-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZMQ8-1", "uniprot_id": "LMTK1_HUMAN", "id": "Q6ZMQ8-1", "name": "Serine/threonine-protein kinase LMTK1", "aln": "------------MSSSFFNPSFAFSSHFDPDGAPLSELSWPSSLAVVAVSFSGLFAVIVLMLACLCCKKGGIGFKEFENAEGDEYAADLAQ-GSPATAAQNGPDVYVLPLTEVSLPMAKQPGRSVQLLKSTDVGRHSLLYLKEIGRGWFGKVFLGEVNSGISSAQVVVKELQASASVQEQMQFLEEVQPYRALKHSNLLQCLAQCAEVTPYLLVMEFCPLGDLKGYLRSCRVAESMAPDPRTLQRMACEVACGVLHLHRNNFVHSDLALRNCLLTADLTVKIGDYGLAHCKYREDYFVTADQLWVPLRWIAPELVDEVHSNLLVVDQTKSGNVWSLGVTIWELFELGTQPYPQHSDQQVLAYTVREQQLKLPKPQLQLTLSDRWYEVMQFCWLQPEQRPTAEEVHLLLSYLCAKGATEAEEEFERRWRSLRPGG-GGVGPGPGAAGPMLGGVVELAAASSFPLLEQFAG-DGFHAD-GDDVLTVTETSRGLNFEYKWEAGRGAEAFP---ATLSPGR-TARLQELCAP----------------------DGAPPGVVPVLSAHSPSLGSEYFIRLEE-----------------AAPAAGHDPDCAG----CAPSPP---ATADQDDDSDGSTAASLAMEPLLGHGPPVDVPWGRGDHYPRRSLARDPLCP-SRSPSPSAGPLSLAEGGAEDADWGVAAFCPAFFED-PLGTSPLGSSGAPPLPLTGEDELEEVGARRAAQRGHWRSN------------VSANNNSGS----------RCPESWDP--VS--AGGHAEGCPSPKQTPRAS--PEPGYPGEP------LLGLQAAS-AQEPGCCPG-LPHLCSAQGLAPAPCLVTPSWTETASSGGDHPQAEPKLATEAEGTTGPRLPLPSVPSPSQE------------------GAPLPSEEASAPDAPDALPDSPTPATGGEVSAIKLAS------------ALNGSSSSPEVEAPSSE-----------------DEDTAEATSGIFTDTSSDGLQARRPDVVPAFRSLQKQVGTPDSLDSLDIPSSASDGGYEVFSPSATGPSGGQPRALDSGYDTENYESPEFVLKEAQEG--------CEPQAFAELASEGEGPGPETRLSTS----LSGLNEKNPYRDSAYFSDLEAEAEATSGPEKKCGG-DRAPGPELG-LPSTGQPSEQVCLR---------------------------PGVSGEAQGSGPGEVLPPLLQLEGSSPEPSTCPSGLVPEPPEPQGPAKVRPGPSPSCSQFFLLTPVPLRSEGNSS----EFQGPPGLLSGPAPQK----------------------RMGGP----------------------------GTPR--APLRLALPGLPAALEGRP------EEEEEDSEDSDESDEELRCYSVQEPSEDSEEEAPAVPVVVAESQSARNLRSLLKMPSLLSETFCEDLERKKKAVSFFDDVTVYLFDQESPTRELGEPFPGAKESPPTFLRGSPGSPSAPNRPQQADGSPNGSTAEEGGGFAWDDDFPLMTA-----KAAFAMALDPAAPAPAAPTPTPAPFSRFTVSPAPTSRFSITHVSDSDAESKRGP-------------------------EAGAGGESKEA-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1Q7U4-1", "uniprot_id": "A0A8M1Q7U4_DANRE", "id": "A0A8M1Q7U4-1", "name": "non-specific serine/threonine protein kinase", "aln": "MRSMKASAFVVVMSSVLFNPSFAFSSHFDPGGSPLSELSWPSSLAVVAVSFSGLFTFVFLMLACLCCKKGDISFKEFENTEGEEGHADLSTLASPTS--QNDPEVYILPLTEVSLPVSKQPSKSFQLLKSADLGRHSLLYIKEMGHGWFGKVLLGEVNAGLSTTQVVVKELKASASVQEQMQFLEEVQPYRVLQHPALLQCLSQSTEVTPYLLVMEHCPLGDVKGYLRSCRAADTVTPDPLILQQMACEIASGLLYLHKHNYIHSDLALRNCLLTSELAVKIGDYGLSHSKYKDDYYVTADQIWVPLRWIAPELIDEVHGNLLVVDQTKASNVWSLGVTIWELFELGNQPYRHYSDRQVLTYAVKEQQLKLPKPLLKVPLCERWYEVMQFCWLQPEQRPVVEEVHLLLSYLCSKGETEVEEDFEKRWNSLRPSLGSGSSHRTPAPEVASS------ASSSFPLLEHFSMADSFQSENGDDILTVTETSQGLNFEYKWEQARAEQPYCSSSASGPLGKNNPHYQDVYYPLCNSTGSCKGESLPLGVSPSYYESDHPGVVPVLSAHSPSVSSEYYIRIEEPVECNINLEDTDLDYSPTVEASNSSLSSAGKRSLIGSQPNSYWSAAKEPISNDYDSDSSLTMEPLQRRVP-SSVEIEQSEAYLSSNDRQHFQCEQSPKKGPDVNLIRRQGSDSNLQRRGSGSHRLEVVDDSPLGMSVSFSSPSLAHCDPYLEPNQRTAERSRANEAYYDMMSPLQKNVPRPHYMSIDIDAGDGLLLGRGSVEDDDDLFSQSMLSNWNSNHSANNNSLSDRRQAVGFQDAYFDLRHPTPSSQIGSLKSRTLEISNSFTYNSIDSLKVHSYIEATDSTPTSSNSHTDSDAGEYLHLCPEGTSGVESSAKCHSVTESLHTHTRQKNIAHKHIKNSTSDLHVGGCSILNSSTLSTEIVDVKENMLVETRISPAQKLNLATNSFGVCVKMVSCSKDTSKSVLECNRLTDSGMVPENSNITLVEINDCKDDCPDIPSGVLVDYPLD--YAEVGNIDLAHGPLQRVNRPRQAEDTINIASSCSP--CEAFSPDSYQTP-IQPKSLDSGYDTENNESPEFILKDLEGNPALSTSVESDESDMVLQMDLDEDVNVMLLHPSSSHLPLISLSERNQYRDSAYFSDYDMENDKS-PCEGSSNFFSRHEGDDIFQLKAEKQDSEKRVRREGHGTESEKGYDISMSKDKTAGLHAKQPSIKKTISNMCSSPTMVPVISTLSPFPPEMGGCLTKESTPDDGIGLESDHSGEEPNSDCYSSTTPEGSSSTQEASGMEEQANGDSKDFSSAESLGSDSTIVDFSGEIIQEEEQDICNNVDNPELPMEGHNEDNIEVNEDSMEGSSIEEALSKPRRDESLERILPALPEDLDVPAPLGNVEEADEEDSEDSDESDEELRSYNIQEQSDESDEEFPVVPVIVSDRSSARHLRSLLKMPSILTQSFCDELESKKKVVSFFDDVTVFLFDQESPTGDLGD-YSFPVEVEPNGQASDVELPRPQDGVTSYEDSSERNASEESETFQWQDDFPLMPSPSTSEPGSEEITTPPNSPVKSPDEKPAPPLSRFSVS-----RFSITHVSDPDMDSMGGN--------------------------SENGAQE--------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *** :*************.*:*******.************:*:.:.***********.*.******:**:* **:: .**:: *..*:**:*********::***.:*.*****:*:*******:**:*:******:****::*:* :*******:.*************.****.*:*. *****:*.:**********.*****:********.:::::*** **:****:*.*:*:**::*::************::*:**:*****:*.**::** *****:***********:****.*********:.**************** *** ::**:***:*:*:********* *::.*.:*****************..***********:** ** **:**:**.****. * . . .. . *:*******:*: *.*: : .**:*******:********* . . : : *: . * : *:: * :. *************:.***:**:* :. *:. . ..** ...* :.:.: ..: .: :**.**** : * : : : * * . .*.. : :: * .:. ..:* *** * *. : . : :. *: .:: :* : ::.. : :. :* ..: . * .: :* : . : .* : : . . . : * . : .: . ... :. ...: *: : .*.:: : *: : : : *..: ...: :. * . : . . : *. : : * * : :.. .:* .: .**::.* . * :. .: * **: . :: *:::*.**.* *.:**.: .. **:::******** *****:**: . . .: . : . .*. . . * * .*..:. ********* : * : . * .. . :: : : * : * . :. . .: * . . * . * * .. *. . *. * ..: : .* . :*. .:..* ...* .* **. * : . * :* *:***:*******.*.:** *::*:** ..***:*:: .***:*********:*:::**::** ***.*********:******** : *: :. . * *. .. * . . *.: .:.* . * *:.****:.. .: * *. :. ...*:***:** *****::**.* :* * . ", "identical_positions": 555, "similar_positions": 398, "identity": "33.37%" }, { "cls_id": "homologset.agr.MGI:1197519", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O54918-1", "uniprot_id": "B2L11_MOUSE", "id": "O54918-1", "name": "Bcl-2-like protein 11", "aln": "MAKQPSDVSSECDREGGQLQPAERPPQLRPGAPTSLQTEPQGNPDG----EGDRCPHGSPQGPLAPPASPGPFATRSPLFIFVRRSSLLSRSSSGYFSFDTDRSPAPMSCDKSTQTPSPPCQAFNHYLSAMASIRQSQEEPEDLRPEIRIAQELRRIGDEFNETYTRRVFANDYREAEDHPQMVILQLLRFIFRLVWRRH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O88498-1", "uniprot_id": "B2L11_RAT", "id": "O88498-1", "name": "Bcl-2-like protein 11", "aln": "MAKQPSDVNSECDREGGQLQPAERPPQLRPGAPTSLQTESQGNPDG----EGDRCPHGSPQGPLAPPASPGPFATRSPLFIFVRRSSLLSRSSSGYFSFDTDRSPAPMSCDKSTQTPSPPCQAFNHYLSAMASIRQSQEEPEDLRPEIRIAQELRRIGDEFNETYTRRAFANDYREAEDHPQMVILQLLRFIFRLVWRRH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O43521-1", "uniprot_id": "B2L11_HUMAN", "id": "O43521-1", "name": "Bcl-2-like protein 11", "aln": "MAKQPSDVSSECDREGRQLQPAERPPQLRPGAPTSLQTEPQGNPEGNHGGEGDSCPHGSPQGPLAPPASPGPFATRSPLFIFMRRSSLLSRSSSGYFSFDTDRSPAPMSCDKSTQTPSPPCQAFNHYLSAMASMR--QAEPADMRPEIWIAQELRRIGDEFNAYYARRVFLNNYQAAEDHPRMVILRLLRYIVRLVWRMH", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "********.******* **********************.****:* *** ****************************:**************************************************:* * ** *:**** ************* *:**.* *:*: *****:****:***:*.***** *", "identical_positions": 170, "similar_positions": 14, "identity": "85.0%" }, { "cls_id": "homologset.agr.MGI:1197522", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P78415-1", "uniprot_id": "IRX3_HUMAN", "id": "P78415-1", "name": "Iroquois-class homeodomain protein IRX-3", "aln": "MSFPQLGYQYIRPLYPSERPGAAGGSGG--SAGARGGLGAGASELNASGSLSNVLSSVYGAPY-AAAAAAAAAQGYGAFLPYAAELPIFPQLGAQYELKDSPGVQHPAAAAAFPHPHPAFYPYG-QYQFGDPSRPKNATRESTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWAPRSRTDEEGNAYGSEREEEDEEEDEEDGKRELELEEEELGGEEEDTGGEGLADDDEDEEIDLENLDGAATEPELSLAGAARRDGDLGLGPISDSKNSDSEDSSEGLEDRPLPVLSLAPAPPPVAVASPSLPSPPVSLDPCAPAPAPASALQKPKIWSLAETATSPDNPRRSPPGAGGSPPGAAVAPSALQLSP--AAAAAAAHRLVSAPLGKFPAWTNRPFPGPPPGPRLHPLSLLGSAPPHLLGLPGAAGHP-AAAAAFARPAEPEGGT-DRCSALEVEKKLLKTAFQPVPRRPQN------------HLDAALVLSALSSS--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P81067-1", "uniprot_id": "IRX3_MOUSE", "id": "P81067-1", "name": "Iroquois-class homeodomain protein IRX-3", "aln": "MSFPQLGYQYIRPLYPPERPGAAGGGGGGSSAGGRSGPGAGASELAASGSLSNVLSSVYGAPYAAAAAAAAAAQGYGAFLPYATELPIFPQLGAQYELKDSPGVQHPATAAAFPHPHPAFYPYG-QYQFGDPSRPKNATRESTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWAPRSRTDEEGNAYGSEREEEDEEEDEEESKRELEMEEEELAGEEEDTGGEGLADDDEDEEIDLENLDSAAAGSELTLAGAAHRNGDFGLGPISDCKTSDSDDSSEGLEDRPLSVLSLAPPPPPVARAPASPPSPPSSLDPCAPAPAPSSALQKPKIWSLAETATSPDNPRRSPPGAGGSPPGAAVAPPTLQLSPAAAAAAAAAHRLVSAPLGKFPAWTNRPFPGPPAGPRPHPLSMLGSAPQHLLGLPGAAGHPAAAAAAYARPAEPESGT-DRCSALEVEKKLLKTAFQPVPRRPQN------------HLDAALVLSALSSS--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZNE0-1", "uniprot_id": "D3ZNE0_RAT", "id": "D3ZNE0-1", "name": "", "aln": "MSFPQLGYQYIRPLYPPERPPAAGGGGGGSSAGGRSGPGAGASELAASGSLSNVLSSVYGAPYAAAAAAAAAAQGYGAFLPYATELPIFPQLGAQYELKDSPGVQHPATAAAFPHPHPAFYPYG-QYQFGDPSRPKNATRESTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWAPRSRTDEEGNAYGSEREEEDEEEDEEEGKRELEMEEEELAGEEEDTGGEGLADDDEDEEIDLENLDSAAAGSELTLAGTAHRNGDFGLGPISDCKNSDSDDSSESLEERPLSVLSLAPAPPPVARAPASPPSPPSGLDPCAPAPAPSSTLQKPKIWSLAETATSPDNPRRSPPGAGGSPPGAAVAPPTLQLSPAAAAAAAAAHRLVSAPLGKFPAWTNRPFPGPPAGPRPHPLSMLGSAPQHLLGLPGAAGHPAAAAAAYARPAEPESGTGDKKNIAVVPWKWRKSYLRQLSSRCQGGPRTTWMLLWSYQLSLRLNFSTIFKSLY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M1PGB3-1", "uniprot_id": "A0A8M1PGB3_DANRE", "id": "A0A8M1PGB3-1", "name": "", "aln": "MSLPQLGYKYIRPLYSTER---------------RGG---AEISVTGSGSLSSALSGVYGAPF------ASTAQGYSAFLPYSSDLSVLNQLSSQYEFKDSPGLQHAG------FPHAAFYPYGHQYQFGDPSRPKNATRESTSTLKAWLSEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWVPKTRTDEDGNVYTSDNEDAE--------KR------------------------DEDEEIDLENIDTEDIE--------DKQDCDYQDDDKSTPKGSDSEEYDDARAEK-----RIIEDEEQIKKSPAEEQEPSNNISPAL----------KPKIWSLAEIATTPDSPKKT------------------------WIQRNCDAQTVRNPL-HVQNWTKMAIS-------AHQMAFT----SHYLGLK-----HQSIANIHVKHAEQRTHSL------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:*****:******..** *.* . .: .*****..**.*****: *::****.*****:::*.:: **.:***:*****:**.. .**.****** *************************.**********************************************.*::****:**.* *:.*: : ** **********:* ::: * . * * ***:: .:. :: : : :... .*. .:.*. ********* **:**.*::: . : * ** :. **: .:. * ::: * *** : * ..: ** . : ", "identical_positions": 189, "similar_positions": 86, "identity": "36.14%" }, { "cls_id": "homologset.agr.MGI:1197523", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A1Z7M5-1", "uniprot_id": "A1Z7M5_DROME", "id": "A1Z7M5-1", "name": "Peptidase S1 domain-containing protein", "aln": "-------------------------------------------------------------------------MQLLLWLCLCLLLLICQSSPSQANILN---------------------------------------------------------------------------------------------------------------------------------------------------TLLGVPAECVHQSGVWPCKLSFSCWLQGGK-------------------------------------HAKGCGSNK-----------------------------------------------------------------------------WLFSCCVAETQHPHQQQHHSPSSPLAN-----------------------------------------------------------------------------------------LVDYGKLKLNLNSLPKR----------IMLR---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RRDDNELLNPKPE-----------------CGVPRTAQNT---------LQKRIIGGRPAQFAEYPWQAHIRIAE-------YQCGGVLISANMVATAAHCIQQAHLADITVYLGELDTQDLGHIHEPLPVEKHGVLQKIIHPRFNFRMTQPDRYDIALLKLAQPTSFTEHILPICLPQYPIRLI-GRKGLIAGWGKTEAHMGHAGTNMLQVASVPIITTLDCIRWHESKQINVEIKAEMFCAGHSDGHMDACLGDSGGPLVIK-ERGRFVLVGITSAGFGCGVDHQPGIYHNVQKTVRWIQEVVARNEP----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A1Z7M7-1", "uniprot_id": "A1Z7M7_DROME", "id": "A1Z7M7-1", "name": "Peptidase S1 domain-containing protein", "aln": "--------------------------------------MLVATDENNTNTTTASRS----TRNTWRWSRLALAVSLFAYCCCASSAATPTTSVTTAALLSGHQLLPWQTAAATAATTPSTARNLYAPHQSFSRHDDISFKDLRQRSDGTVVQSFGSYRTARQ-------------------------------------------------FGGYSTTAQRRSDPAVEIIPAPSVELPQGELITVPKQLVPTMPENVTRQGRRRNYMYIPLQTEGENGSAALLQLRPSRNATLSALGPPADGVAAVAHEFGADLATQGSGPEQPPLALELGPERTERSDLMAAASSTD-------------------------------------KLEYAEPENTSRRVGFQFPSYSLKPASPFHPQAYREDNPIFGDTSAGGYEPQPYSEDASPVPPPTQYEQH----------------------ETRHTRQLYFDSDTASSSFEFPGLVSNSKPHGLKLYRDDVTKFGDINGPITALPQQ----------RPQRGFYFGDTEFRTGPPAPVRQFGPQKNFQEYVGPSEYQGTRKSRYYPYKSSRSPRVVFPTNDNVGT---------------TGPSGPAGSSGPSGNGVYFSDNIAFRDQNFGINELAAVQDVRNDYSLQDLDSASEATSSPQSASTFKEKVDITTDTECQHRGGTCEFFLGC------------------------------WLSGGLIQGTCDGLLRGCCHRTAKSANLGSSDFVGNAVDLTDLPQKNYGPVNNEPS-----------------CGIS-LAKQT---------AQRRIVGGDDAGFGSFPWQAYIRIGS-------SRCGGSLISRRHVVTAGHCVARATPRQVHVTLGDYVIN---SAVEPLPAYTFGVRRIDVHPYFKFTP-QADRFDISVLTLERTVHFMPHIAPICLPEKNEDFL-GKFGWAAGWGALNPGS-RLRPKTLQAVDVPVIENRICERWHRQNGINVVIYQEMLCAGYRNGGKDSCQGDSGGPLMHD-KNGRWYLIGVVSAGYSCASRGQPGIYHSVSKTVDWVSYVVGLTMNI---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0ABK0LTS6-1", "uniprot_id": "A0ABK0LTS6_RAT", "id": "A0ABK0LTS6-1", "name": "Enteropeptidase", "aln": "-KSIRNVAAGHRSISSFEVMVSALFMVLMVLSVGLIVVSWLAVKESETDAAALGKS-HEVRGRFKITSGVTYNPNLQDKFSVDFKVLAFDLQQMIDEIFESSNLKNEYKKSRVFQFENGSVIVLFDLFFAQWVSDENVKEELIQGIEANISSQLVTLHIDLNSIDIAASLSNFSTPFPLTTSDKIASS-LMTTSGSLDNFSTPTVTTTSGSLDNFSTPIGTTTSGNVSVECQPGSRPCANAWDCVATDLFCDGEVNCPDGADEDTGLCATACDGRFLLTGDSGVFQANRYPRPDESGVVCRWIIRVNQGLSVRMSFGKFISHY-TDVLDIYEGIGPSKILRGSFWETDPGTIRIFSNQVTVTFLIKSDEYDYIGFNATYSTFNSSEINNYEKINCTFDDGFCFWTQDLDDDNEWERNQMARFPCYTGPFSDHTFGNESGFYISTPAEQAWKSERVGLSSLSLGFTSEPVCLHFWYYMCCENVYNLNIHVSSTETTDKIVFQRQGNYGRNWNYGQVTLNETVEFKVVFNAFRNR-GCSTIALDDISLTNGICSESPYPEPTLVPTPPPEHPTDCGGPFELWEPNTTFSSPNFPDNYPNQAFCIWNLNAQSGKNIQLHFQEFDLENINDVVEVRDGVKFDSLLLAVYTGRGPVKDLFSTTNRMTVIFDTDMKNGGKGFKANFTSGYYLGIPQPCQDDEFQCKDGNCIPMGNLCDSYQHCSDGSDEAHCVRFLNGTQSNNGLVQFNIHNIWHIACAEPWTTQISNEVCHLLGLGSANSSMPILSTGGGPFVRLNEAPNGSLILTPSLQCSQDSLILLQCNHKSCGEKMVTQK----------VGPKIVGGSDTQAGAWPWVVALYYRDRS--GDRLLCGASLVSSDWLVSAAHCVYRRN-LDPTRWTAVLGLHMQSNLTSPQ-VVRRVVDRIVINPHYDKRR---KVNDIAMMHLEFKVNYTDYIQPICLPEENQTFTPGRMCSIAGWGYNKINA-GSTVDVLKEADVPLVSNEKCQQQLP----EYDITESMLCAGYEEGGTDSCQGDSGGPLMCQ-ENNRWFLVGVTSFGVQCALPNHPGVYARVSQFIEWIHSFLH--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97435-1", "uniprot_id": "ENTK_MOUSE", "id": "P97435-1", "name": "Enteropeptidase", "aln": "MKSSRDEAVGHHSISSFEVMLSALFIMLMVFSIGLIAVSWLAVKESEGD-AALGKS-HEVRGTFKITSGVTYNPNLQDKHSVDFKVLAFDLQQMIDEIFESSSLKNEYEKSKVFQFEKGSVIVLFDLFFAQWVSDKNVKEELIQGIEANISSQLVTLHIDLNSIDITASLSDFTTAVPVTTSDKLTTSSPMTTSASLGNLSTTVAATTSAPLCNLSTATFATTSGHVSIECQPGSRPCAHAWNCVATDLFCDGEVNCPDGSDEDTGLCATACDGRFLLTGDSGVFQADRYPRPDESGVVCRWIIRVNQGLSIRMNFGSFIPHY-TDVLDIYEGIGPSKILRGSFWETDPGTIRIFSNLVTVTFLIKSDEYDYIGFNATYSTFNNSELNNYEKIDCTFDDGFCFWTQDLDDDNEWERIQVTTFPCYTGPRFDHTYGNGSGFYISTPTEQGWRSERVGLSSLSLDLTSEPVCLHFWYYMCCENVYNLNIHISSAETTDKIVFQRKGNYGRNWNYGQVTLNETGEFKVVFNAFRNR-GCSTIALDDISLTNGICSQSPYPEPTLVPTPPPELPTDCGGPFELWEPNSTFSSPNFPDKYPNQASCIWNLNAQRGKNIQLHFQEFDLENINDVVEVRDGGEFDSLLLAVYTGPGPVKDLFSTTNRMTVIFTTNMETRRKGFKANFTSGYYLGIPEPCQDDEFQCKDGNCIPLGNLCDSYPHCRDGSDEASCVRFLNGTRSNNGLVQFNIHSIWHIACAENWTTQISNEVCHLLGLGSANSSMPISSTGGGPFVRVNQAPNGSLILTPSLQCSQDSLILLQCNHKSCGEKKVTQK----------VSPKIVGGSDAQAGAWPWVVALYHRDRS--TDRLLCGASLVSSDWLVSAAHCVYRRN-LDPTRWTAVLGLHMQSNLTSPQ-VVRRVVDQIVINPHYDRRR---KVNDIAMMHLEFKVNYTDYIQPICLPEENQIFIPGRTCSIAGWGYDKINA-GSTVDVLKEADVPLISNEKCQQQLP----EYNITESMICAGYEEGGIDSCQGDSGGPLMCQ-ENNRWFLVGVTSFGVQCALPNHPGVYVRVSQFIEWIHSFLH--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P98073-1", "uniprot_id": "ENTK_HUMAN", "id": "P98073-1", "name": "Enteropeptidase", "aln": "MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRG-AALGQS-HEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDI---------------------------------------------LDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYY-TDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNK-ILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQD----------ITPKIVGGSNAKEGAWPWVVGLYYGG------RLLCGASLVSSDWLVSAAHCVYGRN-LEPSKWTAILGLHMKSNLTSPQ-TVPRLIDEIVINPHYNRRR---KDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWG-TVVYQ-GTTANILQEADVPLLSNERCQQQMP----EYNITENMICAGYEEGGIDSCQGDSGGPLMCQ-ENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TAA8-1", "uniprot_id": "A0AB32TAA8_DANRE", "id": "A0AB32TAA8-1", "name": "", "aln": "MGRKR------CNFSSTEVLLTTLVALLFAVCIGLIVVTSLALDSKATNGEDEDETGSEFTGKLVISNGTVFTEELLNKNSAQFKALAYDTEQRISDAYRRSSLKEQFRSSKVNEFSEGSVVVDFDVFFRGVLDSEMAQKQLVDGLQQGESG-NDGLVIDIGSVEVT---------------------------------------------DKPTTTQRPSTT--KPVNCPDEQKLCADGKTCIPQTDFCDGIQNCPDGSDEKPSVCATVCDGQFLLLGSSGSFHSKNFS--DDGLAACRWIIRVTDGLAIKLIFHTFDTEQDLDFLALYEGIGSTKTLAYFLSGTSPGDLWLLSHEATAEFNSQTG--NRQGFNATYMAVNISDFSNEEKINCSFEEDFCLWRKELNDDGEWVRAQGETPPSDTGPSFDHTTGNQSGYYIVTPRTSGNWERKFRLYSLPLTPTKELMCLQFWYHMFGEHVRRLTVTSEG-RSTITVLFQKEGNYGDNWNYGQATLNISADTVVVFEAQKSSGILNDIALDDISIVPGSCEQIP-PDPTPVP-PPVNPPEDCGGPFDLYEPNSTFSSPNYPDGYGHNASCMWTLHAKEGQNIQLHFQDVALEASYDVLEIRDGVEPYSDLLGVLTGERSFPDLFSTTSQMTVMLFTDAKTNNRGFLANFSAGVNLGQPDPCPSGQFQCGAGACVFNASVCDGVEDCPNGTDEADCVHVIKDNTTGTERLKLQIQNNLYTVCAQDWTPQFSDFFCRYLGYRSGVASFSITVEGDGPFTTVNVNSNGSLELKPSDKCLSEKIVSLHCNNQPCGVRKVPSKSKIIEETDGKKEGRVVGGQDAQRGAWPWMVSLQWLG------GHACGATLIDREWLITAAHCVYGRN-VQLSNWAAVLGLHAQFETINPN-KQVFSVDQVIMHKHYNKRT---KESDFALMHLKTPVSYTDYVQPICLPDPGAHFEEGRKCFIAGWG-LLSES-GLKADVLQQAVVPLLSNTQCQKWLP----EYNFTERMMCAGYAEGGVDTCQGDSGGPLMCE-EEGHWVLVGATSFGIGCGRPQRPGAYARVSQFVDWVAENRRLYSDWKGS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q05319-1", "uniprot_id": "STUB_DROME", "id": "Q05319-1", "name": "Serine proteinase stubble", "aln": "-------------MKQPTLIRPRLRHRRSTPAAATKMCPKRHWLVNNRAAGSRGSGGAAARSRRSLDQIVEVLVALIVVNCLATAAAALITPPDSLESLGSLGIPSSSASSSEDDDDMSSGFYRIPHRLEGYPQLQQLQRG-----------------------------------------------------------------------QNFKISPKPCSFGRVEGTCMFVWECIKSEGKHVGMCVDSFMFGSCCTHNYTDN-IVLPQTAFSYTRPTKPLTLRPRPPAAPYKPMISGMTTIERPHGAGTLVIRPSGPHHQGTLARPHPPPYQSKPTTASDLHGSAS-----------------------------------HPSSSSSSSSSSNPNSIWHTSTQQQQQQQHQQNQQNHWQMTTEPSFITKPRPTG------------------------------------------------------------------------------WTKPGIVNLPMPARPSK-----------PSKPTKKPIVYDRTPPPPPSVPPSTSTSTTSTSLIWPAQTHPPQPHRPTRPQLSPG--------------------------TSLAASSSSHWPSSTTSTTSSTTSTTTTTTTTRRTTTPTTTTRRTTTNKPTRPYQRPTTATSSSSTSTTSSKTPTTTRPISS-----------------------------------------SSSSSSGIVTSSQRPTQPTHRTPVLATSGIETNEISDSSIPDAGALGHVKTISAAR-------------SECGVPTLARP-----------ETRIVGGKSAAFGRWPWQVSVRRTSFFGFSSTHRCGGALINENWIATAGHCVDDLLISQIRIRVGEYDFS---HVQEQLPYIERGVAKKVVHPKYSFLT---YEYDLALVKLEQPLEFAPHVSPICLPETD-SLLIGMNATVTGWGRLSEGG--TLPSVLQEVSVPIVSNDNCKSMFMRAGRQEFIPDIFLCAGYETGGQDSCQGDSGGPLQAKSQDGRFFLAGIISWGIGCAEANLPGVCTRISKFTPWILEHVR--------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . : . . : : . : . ** . :::** : . :** . : **. *:. : :*.**: : . . : . :: :. *:::: * : :: *****: : * :*** . *: . **:: . * : : ::***: * *:* ******* . : .:: * * * * *. ** :.: *: ", "identical_positions": 49, "similar_positions": 66, "identity": "4.44%" }, { "cls_id": "homologset.agr.MGI:1197524", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5U2N3-1", "uniprot_id": "PITM1_RAT", "id": "Q5U2N3-1", "name": "Membrane-associated phosphatidylinositol transfer protein 1", "aln": "MLIKEYHILLPMSLDEYQVAQLYMIQKKSREESSGEGSGVEILANRPYTDGPGGNGQYTHKVYHVGSHIPGWFRALLPKAALQVEEESWNAYPYTRTRYTCPFVEKFSIEIETYYLPDGGQQPNVFNLSGAERRQRILDTIDIVRDAVAPGEYKAEEDPRLYRSVKTGRGPLADDWART-----------AAQTGPLMCAYKLCKVEFRYWGMQAKIEQFIHDVGLRRVMLRAHRQAWCWQDEWIELSMADIRALEEETARMLAQRMAKCNTGSEGPEAQTPGKPSTETQPGTRTAGTPDGPEAP-------PGPDASPDAS-------------------------FGKQWSSSSRSSYSSQHG-----GGVSPQS---------LSEWRMQNIARDSENSSEEEFFDAHEG-FSDSDEVFPKEMTKWNSNDFIDAFASPTEVEGVPDPA-------------IMATKGIEDEARAPRDSEGLDG------TGDLGVEACSVHALFLILHSGSILDSGPGDTNSKQADVQTLSTAFEAVTRVHFPEALGHVALRLVPCPPICAAAYALVSNLSPYSHDGDSLSRSQD---HIPLAALPLLATSSSRYQGAVATVIARTNQAYAAFLRSSEGTGFCGQVVLIGDGVGGILGFDALCHSASAGTGSRGSSRRGSMNNEMLSPEVGPVRDPLADGVEVLGRASPEPSALPAQRTSSDMANPDPDGSQNSLQVAPTVTS-GEPRRASTASCPPASS-EAPDGPTNAARLDFKVSGFFLFGSPLGLVLALRKTVMPALEVAQMRPACEQIYNLFHAADPCASRLEPLLAPKFQAIAPLAVPRYQKFPLGDGSSLLLADTLQTHSSLFLEELEMMVPSTPTSASGAFWKGNELGNEPAAQPAAPSTTSEVVKILDRWWGNKRIDYSLYCPEALTAFPTVTLPHLFHASYWESADVVAFILRQVIEKERPQLTECEEP---SIYSPAFPREKWQRKRTQVKIRNVTSNHRASDTVVCEGRPQVLNGRFMYGPLDVVTLTGEKVDVYVMTQPLSGKWIHFGTEVTNSSGRLTFPVPSERALGIGVYPVRMVVRGDHTYAECCLTVVSRGTEAVVFSIDGSFTASVSIMGSDPKVRAGAVDVVRHWQDSGYLIVYVTGRPDMQKHRVVAWLSQHNFPHGVVSFCDGLTHDPLRQKAMFLQSLVQEVELNIVAGYGSPKDVAVYAALGLSPSQTYIVGRAVRKLQAQCQFLSDGYVAHLGQLEAGSHSHAPSGPPRAALAKSSYAVAAPVDFLRKQSQLLRSRGPSQVDLEGPGTPPTTLARGKTRSISLKLDSEE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35954-1", "uniprot_id": "PITM1_MOUSE", "id": "O35954-1", "name": "Membrane-associated phosphatidylinositol transfer protein 1", "aln": "MLIKEYHILLPMSLDEYQVAQLYMIQKKSREESSGEGSGVEILANRPYTDGPGGNGQYTHKVYHVGSHIPGWFRALLPKAALQVEEESWNAYPYTRTRYTCPFVEKFSIEIETYYLPDGGQQPNVFNLSGAERRQRIVDTIDIVRDAVAPGEYKAEEDPRLYRSAKTGRGPLADDWART-----------AAQTGPLMCAYKLCKVEFRYWGMQAKIEQFIHDVGLRRVMLRAHRQAWCWQDEWIELSMADIRALEEETARMLAQRMAKCNTGSEGPEAQTPGKSSTEARPGTSTAGTPDGPEAP-------PGPDASPDAS-------------------------FGKQWSSSSRSSYSSQHG-----GGVSPQS---------LSEWRMQNIARDSENSSEEEFFDAHEG-FSDSDEVFPKEMTKWNSNDFIDAFASPTEVEGVPDPT-------------VMATKGIEDGARAPRDSEGLDG------AGDLVVEACSVHALFLILHSGSILDSGPGDTNSKQADVQTLSTAFEAVTRVHFPEALGHVALRLVPCPPICAAAYALVSNLSPYSHDGDSLSRSQD---HIPLAALPLLATSSSRYQGAVATVIARTNQAYAAFLRSSEGTGFCGQVVLIGDGVGGILGFDALCHSASAGPGSRGSSRRGSMNNEMLSPEVGPVRDPLADGVEVLGRASPEPSALPAQRTFSDMANPDPDGSQNSLQVASTATSSGEPRRASTASCPPASS-EAPDGPTNAARLDFKVSGFFLFGSPLGLVLALRKTVMPALEVAQLRPACEQIYNLFHAADPCASRLEPLLAPKFQAIAPLAVPRYQKFPLGDGSSLLLADTLQTHSSLFLEELEMMVPSTPTSASGAFWKGSELGNEPASQTAAPSTTSEVVKILDRWWGNKRIDYSLYCPEALTAFPTVTLPHLFHASYWESADVVAFILRQVIEKERPQLTECEEP---SIYSPAFPREKWQRKRTQVKIRNVTSNHRASDTVVCEGRPQVLNGRFMYGPLDVVTLTGEKVDVYVMTQPLSGKWIHFGTEVTNSSGRLTFPVPSERALGIGVYPVRMVVRGDHTYAECCLTVVSRGTEAVVFSIDGSFTASVSIMGSDPKVRAGAVDVVRHWQDSGYLIVYVTGRPDMQKHRVVAWLSQHNFPHGVVSFCDGLTHDPLRQKAMFLQSLVQEVELNIVAGYGSPKDVAVYAALGLSPSQTYIVGRAVRKLQAQCQFLSDGYVAHLGQLEAGSHSHAPSGPPRAALAKSSYAVAAPVDFLRKQSQLLRSRGPSQVDREGPGTPPTTLARGKTRSISLKLDSEE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00562-1", "uniprot_id": "PITM1_HUMAN", "id": "O00562-1", "name": "Membrane-associated phosphatidylinositol transfer protein 1", "aln": "MLIKEYHILLPMSLDEYQVAQLYMIQKKSREESSGEGSGVEILANRPYTDGPGGSGQYTHKVYHVGSHIPGWFRALLPKAALQVEEESWNAYPYTRTRYTCPFVEKFSIEIETYYLPDGGQQPNVFNLSGAERRQRILDTIDIVRDAVAPGEYKAEEDPRLYHSVKTGRGPLSDDWART-----------AAQTGPLMCAYKLCKVEFRYWGMQAKIEQFIHDVGLRRVMLRAHRQAWCWQDEWTELSMADIRALEEETARMLAQRMAKCNTGSEGSEAQPPGKPSTEARSAASNTGTPDGPEAP-------PGPDASPDAS-------------------------FGKQWSSSSRSSYSSQHG-----GAVSPQS---------LSEWRMQNIARDSENSSEEEFFDAHEG-FSDSEEVFPKEMTKWNSNDFIDAFASPVEAEGTPEPG-------------AEAAKGIEDGAQAPRDSEGLDG------AGELGAEACAVHALFLILHSGNILDSGPGDANSKQADVQTLSSAFEAVTRIHFPEALGHVALRLVPCPPICAAAYALVSNLSPYSHDGDSLSRSQD---HIPLAALPLLATSSSRYQGAVATVIARTNQAYSAFLRSPEGAGFCGQVALIGDGVGGILGFDALCHSANAGTGSRGSSRRGSMNNELLSPEFGPVRDPLADGVEGLGRGSPEPSALPPQRIPSDMASPEPEGSQNSLQAAPATTSSWEPRRASTAFCPPAASSEAPDGPSSTARLDFKVSGFFLFGSPLGLVLALRKTVMPALEAAQMRPACEQIYNLFHAADPCASRLEPLLAPKFQAIAPLTVPRYQKFPLGDGSSLLLADTLQTHSSLFLEELEMLVPSTPTSTSGAFWKGSELATDPPAQPAAPSTTSEVVKILERWWGTKRIDYSLYCPEALTAFPTVTLPHLFHASYWESADVVAFILRQVIEKERPQLAECEEP---SIYSPAFPREKWQRKRTQVKIRNVTSNHRASDTVVCEGRPQVLSGRFMYGPLDVVTLTGEKVDVYIMTQPLSGKWIHFGTEVTNSSGRLTFPVPPERALGIGVYPVRMVVRGDHTYAECCLTVVARGTEAVVFSIDGSFTASVSIMGSDPKVRAGAVDVVRHWQDSGYLIVYVTGRPDMQKHRVVAWLSQHNFPHGVVSFCDGLTHDPLRQKAMFLQSLVQEVELNIVAGYGSPKDVAVYAALGLSPSQTYIVGRAVRKLQAQCQFLSDGYVAHLGQLEAGSHSHASSGPPRAALGKSSYGVAAPVDFLRKQSQLLRSRGPSQAEREGPGTPPTTLARGKARSISLKLDSEE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P43125-1", "uniprot_id": "RDGB_DROME", "id": "P43125-1", "name": "Protein retinal degeneration B", "aln": "MLIKEYRIPLPLTVEEYRIAQLYMIAKKSREESHGEGSGVEIIINEPYKDGPGGNGQYTKKIYHVGNHLPGWIKSLLPKSALTVEEEAWNAYPYTRTRYTCPFVEKFSLDIETYYYPDNGYQDNVFQLSGSDLRNRIVDVIDIVKDQLWGGDYVKEEDPKHFVSDKTGRGPLAEDWLEEYWREVKGKKQPTPRNMSLMTAYKICRVEFRYWGMQTKLEKFIHDVALRKMMLRAHRQAWAWQDEWFGLTIEDIRELERQTQLALAKKMGGGEECSDDSVSEPYVSTAATAASTTGSERKKSAPAVPPIVTQQPPSAEASSDEEGEEEEDDDEDENDAIGTGVDLSANQGGSAQRSRSQSIQMAQKGKFGSKGALHSPVGSAHSFDLQVANWRMERLEVDSKSNSDEEFFDCLDTNETNSLAKWSSLELLGEGDDSPPPHGGPSSAASVGGRGNSRQEDSIFNQDFLMRVASERGNKRQLRSSASVDRSHDSSPPGSPSTPSCPTTILILVVHAGSVLDAAS-ELTAKKSDVTTFRGSFEAVMRQHYPSLLTHVTIKMVPCPSICTDALGILSSLSPYSFDASPSAADIPNIADVPIGAIPLLSVASPEFHETVNKTVAAANIVYHEFLKSEEGHGFSGQIVMLGDSMGSLLAYEALCRSN----GSQPGTASGASN---------------SGGDAATNINTHNPLSPRNSRLDDDERFIEADLDAKRLLVAP------SPRRRRSSSSS----------DSRATKLDFEVCDFFMFGSPLSVVLAARK--LHDAKAALPRPNCHQVYNLFHPTDPIASRLEPLLSARFSILAPVNVPRYAKYPLGNGQPLHLLEVIQSHPQHFNDGNNLLAGRRLSDAS---------MQSTISGLIENVSLSTIHALQNKWWGTKRLDYALYCPEGLSNFPAHALPHLFHASYWESPDVIAFILRQIGKFEGIPFVGSNDDKDNASFHPGQPREKWIKKRTSVKLKNVAANHRANDVIVQEGREQRLNARFMYGPLDMITLHGEKVDVHIMKDPPAGEWTFLSTEVTDKNGRISYSIPDQVSLGYGIYPVKMVVRGDHTSVDCYMAVVPPLTECVVFSIDGSFTASMSVTGRDPKVRAGAVDVCRHWQELGYLLIYITGRPDMQQQRVVSWLSQHNFPHGLISFADGLSTDPLGHKTAYLNNLVQNHGISITAAYGSSKDISVYTNVGMRTDQIFIVGKVGKKLQSNATVLSDGYAAHLAGLQAVGGSRPAKGNARMVIPRGCFNLPGQTANPRRRR---------------------YLERKTVSSCCLMVFQTT", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******:* **::::**::****** ******* ********: *.**.*****.****:*:****.*:***:::****:** ****:********************::***** **.* * ***:***:: *:**:*.****:* : *:* ****: : * *******::** . :.:. .** ***:*:*********:*:*:*****.**::*********.***** *:: *** **.:* **::*. : *:.. ::. ..:: : . : . . ..* .* *..:**.* . *. * *:* :*:* *.: . :::***:.: **:..*:*****. : ::* :.. :.:* ....* .. .. . . .. : *.* .:* .*. . :*.. *:*::*:*.:**:.. : .:*::** *: :**** * *:*. * **::::****.**: * .::*.*****.*... : . .:*:.*:***:.:*..:: :* ..:* :* .* **:* ** **.**:.::**.:*.:*.::***:* **: .: *: * :.* . : :* : .* .* :.: . : * .*. .*** :: .. : :::***:*..**:*****.:*** ** : :.* ** *.*:*****.:** ********:.:*. :**: **** *:***:*..* * :.:*:*.. * : :::. :.:* .. : : * : : ::***.**:**:*****.*: **: :************.**:******: : * :. .:: : : *. ***** :***.**::**::****.*.:* *** * *..********::** ******::*.:* :*:* .:.****:..**:::.:* : :** *:***:******** .:* ::**. **.************:*: * *********** ****: ***::*:*******::***:**********::**.***: *** :*: :*:.***: :.*.*.***.**::**: :*: ..* :***:. :***::. .*****.***. *:* . *:...* .* .: :..: :.. . *:: * * .. * .* : . ", "identical_positions": 540, "similar_positions": 394, "identity": "40.69%" }, { "cls_id": "homologset.agr.MGI:1197526", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LNN7-1", "uniprot_id": "A0ABK0LNN7_RAT", "id": "A0ABK0LNN7-1", "name": "", "aln": "--------------------------MSYPQGYLYQAPGSLALYSCPAYG---ASALAAPRSEELARSASGS---AFSPYPGSAAFTAQAATGFGSPLQYSADAAAAAAAG-------------------------------------FPSYMGSPYDTHTTGMTGAIS----------------------------------YHPYGSAAYPYQLN------DPAYRKNATRDATATLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWAPRNKSEDEDE--DEGDASRSKEENPDKAQDGTETSAEDEGISLHVDSLTDHSCSAESDGEKLPCRAGDPLCESGSECKDKFEDLEDEEDDEDECERDLVPPKPVTSSPLTGVEAPLLSPAPEAAPRGGSGGKTPLGSRTSPGAPPPASKPKLWSLAEIATSDLKQPSLGPGCGPPGLP-----------AAAAPASSGAPPGGSPYSASPLLGRHLYY-------------TSPFYGNYTNYGNLNAALQ---GQGLLRYNTAASSPGETLHAIPKAASDAG---------------------------------KAGSHSLESHYRPPGGGYEPKKGRCHNCFGKKKSGGHSPFPSS------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P81066-1", "uniprot_id": "IRX2_MOUSE", "id": "P81066-1", "name": "Iroquois-class homeodomain protein IRX-2", "aln": "--------------------------MSYPQGYLYQAPGSLALYSCPAYG---ASALAAPRSEELARSASGS---AFSPYPGSAAFTAQAATGFGSPLQYSADAAAAAAAG-------------------------------------FPSYVGSPYDTHTTGMTGAIS----------------------------------YHPYGSAAYPYQLN------DPAYRKNATRDATATLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWAPRNKSEDEDE--DEGDASRSKEESSDKAQDGTETSAEDEGISLHVDSLTDHSCSAESDGEKLPCRAGDALCESGSECKDKFEDLEDEEDEEDECERDLAPPKPVTSSPLTGVEAPLLSPAPEAAPRGGSGGKTPLGSRTSPGAPPPASKPKLWSLAEIATSDLKQPSLGPGCGPPGLP-----------AAAAPASTGAPPGGSPYSASPLLGRHLYY-------------TSPFYGNYTNYGNLNAALQ---GQGLLRYNTAASSPGETLHAMPKAASDTG---------------------------------KAGSHSLESHYRPPGGGYEPKKDTSEGCAVVG-AGVQTYL---------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BZI1-1", "uniprot_id": "IRX2_HUMAN", "id": "Q9BZI1-1", "name": "Iroquois-class homeodomain protein IRX-2", "aln": "--------------------------MSYPQGYLYQAPGSLALYSCPAYG---ASALAAPRSEELARSASGS---AFSPYPGSAAFTAQAATGFGSPLQYSADAAAAAAG--------------------------------------FPSYMGAPYDAHTTGMTGAIS----------------------------------YHPYGSAAYPYQLN------DPAYRKNATRDATATLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWAPRNKSEDEDE--DEGDATRSKDESPDKAQEGTETSAEDEGISLHVDSLTDHSCSAESDGEKLPCRAGDPLCESGSECKDKYDDLEDDEDDDEEGERGLAPPKPVTSSPLTGLEAPLLSPPPEAAPRGGR--KTPQGSRTSPGAPPPASKPKLWSLAEIATSDLKQPSLGPGCGPPGLP-----------AAAAPASTGAPPGGSPYPASPLLGRPLYY-------------TSPFYGNYTNYGNLNAALQ---GQGLLRYNSAAAAPGEALHTAPKAASDAG---------------------------------KAGAHPLESHYRSPGGGYEPKKDASEGCTVVG-GGVQPYL---------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "M9PI45-1", "uniprot_id": "M9PI45_DROME", "id": "M9PI45-1", "name": "", "aln": "MTVHSNETGICLVMNAVSTHLATSSPNTPPTNAPQSPPSTLPTLACPAAQPLSAPGIAGPGHSGMVTSTVPPGARSTSPCGPSAGLPALSLVGAPPPGPHSSAPGGAPAPGAGNPPNRCCDTGRTIYTDPVSGQTICSCQYDMLNYQRLAAAGGVPLGVYPEGMSAYLSGIAADQPPFYANPAGIDLKENLVAGASPWPYPSMYHPYDAAFAGYPFNSYGMDLNGARRKNATRETTSTLKAWLNEHKKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWEPRNRVDDDDANIDDDDDKNTEDNDLLDAKDSGVGSTDDKDRSGRLGDMMTDRPGESNNSEWSESRPGSPNGSP---------DLYDRPGSMPPGAHPLFHPAALHHHFRPPAGSPPDIAAYHHHQQQLLQQHQQAQQNSLQTAVGGTAKPRIWSLADMASKDSKDSSSGAKDNHPELPPAHPGFYGHPGQQPSPGKILSPLAARIPNYSPYVRPDLYRGFYGPAAAHLGAPTQEFLEHQRTFGASLAAHNGPLGMNPLLWKAAVSGAANGHHFAPLSLTTSGGSSGGQQVAPPPVASPSASSSSSSMGCDVVHIPTSSGQSAAQHMMGPISSNSTASSSSSHSGKISPGVNVTSLSAKPXHPSAASPDPELGAAPIASPISAFRSLIAFREQQKLTLLRP", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * . ..*.:*. :*** *..:*.* . :. *: . : ** **.:.* : .* .* :*: ...*.* :.: * * ..:. **:. :* ****.:* * :* : * ******::*:*********:******************************************* ***: :*:* *:.* ..::::. .*::. *::*:. * ::..: . . ..:.* .*.*.. .. ** * .. : * * .: . :* .. . : : ..: * ::**::****::*:.* *:.* *. . * ** .:*.. :* .. ** : ** *. * : .:* ** : * . * :::*.:...: * * : : :* .:..:. .* * .. .. .. . . . . : ", "identical_positions": 146, "similar_positions": 156, "identity": "21.13%" }, { "cls_id": "homologset.agr.MGI:1197527", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A6J4-1", "uniprot_id": "D4A6J4_RAT", "id": "D4A6J4-1", "name": "DNA topoisomerase", "aln": "MIFPVTLLAFQWQRRPGGRALSRAAMEVAFR--GVRKVLCVAEKNDAAKGIADLLSNGRMRRKEGLSKFNKIYEFDYHLY-----GQNVTMIMTSVSGHLLAHDFQMQFRKWQSCNPLVLFEAEIEKYCPENFIDIKKTLERETQHCQALVIWTDCDREGENIGFEIIHVCK---AVKPNLQVLRARFSEITHHAVRAACEHLTEPDQRVSDAVDVRQELDLRIGAAFTRFQTLRLQRIFP---------------EVLAEQLISYGSCQFPTLGFVVERFKAIQAFVPEVFHRIKVTHDHKDG--TVEFNWKRYRLFNHTACLVLYQLCMEDP--MATVVEVRSKPKSKWRPQALDTVELEKLASRKLRINAKETMRIAEKLYTQGYISYPRTETNIFPKDLNLVTLVEQQTQ--------DPHWGAFAQNILERGGPTPRN-------GNKSDQAHPPIHPTKYT---SSLQGDDRRLYEFIVRHFLACCSQDAQGQETTVEIDIAQERFVAHGLIILARNYLDVYPYDHWS-DKLLPVYEQGFRFQPSTVEMVDGETSPPQLLTEADLIALMEKHGIGTDATHAEHIETIKARMYVG---LTSDKRFLPGHLGMGLVEGYDSMGYE--MSKPNLRAELEADLKLICEGKKDKFQVLRQQVQKYKQVFIEAVAKAKKLDEALSQYLGER--TEVAQQEEIYPAMP-----EPVRKCPQCNKD-MVLKTKK-SGGFYLSCTGFPECRSAVWFPDSVLEASRDSSVCSVCQP---APVYRLKLKFKRGSLPP-------------------SMPLEFVGCIG---------------------------------------------------------------------------------------------------------------------------------GCDETLKEIFG---------LRFSRAPPRASQP-------------------------------------SGHLQASQAL--------------------NRMD-SSQRSLSQPLVNRHTGPSKAVAQTLLPPTAAAEGNSVTCN-CGREAVLLTVRKQGPNQGRHFYKCSGGD-CNFFLWADSSHPTGGGPPTSVSRPPGNS-------VGCP------SGFG-SHMDGFG----------------SLGGDGDGG-ASCLCGQPAVTRTVQKDGPNKGRQFHTCAKPREQQCGFFQWVDENMAPGSFAAPAWPGGRGKAQRPEAASKRQRAGSLDAGSTVKKPRKCSLCHQPGHTRPFCPQNR----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70157-1", "uniprot_id": "TOP3A_MOUSE", "id": "O70157-1", "name": "DNA topoisomerase 3-alpha", "aln": "MIFPVTLLAFQWHRRPGGRALSRAAMEVAFR--GVRKVLCVAEKNDAAKGIADLLSNGRMRRKEGLSKFNKIYEFDYHLY-----GQNVTMIMTSVSGHLLAHDFQMQFRKWQSCNPLVLFEAEIEKYCPENFIDIKKTLERETHHCQALVIWTDCDREGENIGFEIIHVCK---AVKPNLRVLRARFSEITPHAVRTACENLTEPDQRVSDAVDVRQELDLRIGAAFTRFQTLRLQRIFP---------------EVLAEQLISYGSCQFPTLGFVVERFKAIQAFVPEVFHKIKVTHDHKDG--TVEFNWKRYRLFNHTACLVLYQLCMEDP--MATVVEVRSKPKSKWRPQALDTVELEKLASRKLRINAKETMRIAEKLYTQGYISYPRTETNIFPKDLNLVALVEQQTV--------DPHWGAFAQTILERGGPTPRN-------GSKSDQAHPPIHPTKYT---SGLQGDDRRLYEFIVRHFLACCSQDAQGQETTVEIDIAQERFVAHGLIILARNYLDVYPYDHWS-DKLLPVYEQGSHFQPSTVEMVDGETSPPQLLTEADLIALMEKHGIGTDATHAEHIETIKARMYVG---LTSDKRFLPGHLGMGLVEGYDSMGYE--MSKPDLRAELEADLKLICEGKKDKFQVLRQQVQKYKQVFIEAVAKAKKLDEALSQYLGER--TEMAQQEEIYPAMP-----EPVRKCPQCNKD-MVLKTKK-SGGFYLSCMGFPECRSAVWFPDSVLEASRDNSVCSVCQP---PPVYRLKLKFKRGSLPP-------------------AMPLEFVGCIG---------------------------------------------------------------------------------------------------------------------------------GCDETLKEIFG---------LRFPRALPRASQP-------------------------------------SGHLQASQAL--------------------NRMD-SSQHNLSQPLVNRHTRPSKTVAQALLPPTTAGESNSVTCN-CGREAVLLTVRKQGPNQGRHFYKCSNGD-CNFFLWADSSHSTGGGTPTSASGPPGSS-------VGCP------SSVG-SHMDGFG----------------SLGSDSDGG-TPCLCGQPAVTRTVQKDGPNKGRQFHTCAKPREQQCGFFQWVDENVAPGSFAAPAWPGGRGKAQRPEAASKRPRAGSSDAGSTVKKPRKCSLCHQPGHTRTFCPQNR----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13472-1", "uniprot_id": "TOP3A_HUMAN", "id": "Q13472-1", "name": "DNA topoisomerase 3-alpha", "aln": "MIFPVARYALRWLRRPEDRAFSRAAMEMALR--GVRKVLCVAEKNDAAKGIADLLSNGRMRRREGLSKFNKIYEFDYHLY-----GQNVTMVMTSVSGHLLAHDFQMQFRKWQSCNPLVLFEAEIEKYCPENFVDIKKTLERETRQCQALVIWTDCDREGENIGFEIIHVCK---AVKPNLQVLRARFSEITPHAVRTACENLTEPDQRVSDAVDVRQELDLRIGAAFTRFQTLRLQRIFP---------------EVLAEQLISYGSCQFPTLGFVVERFKAIQAFVPEIFHRIKVTHDHKDG--IVEFNWKRHRLFNHTACLVLYQLCVEDP--MATVVEVRSKPKSKWRPQALDTVELEKLASRKLRINAKETMRIAEKLYTQGYISYPRTETNIFPRDLNLTVLVEQQTP--------DPRWGAFAQSILERGGPTPRN-------GNKSDQAHPPIHPTKYT---NNLQGDEQRLYEFIVRHFLACCSQDAQGQETTVEIDIAQERFVAHGLMILARNYLDVYPYDHWS-DKILPVYEQGSHFQPSTVEMVDGETSPPKLLTEADLIALMEKHGIGTDATHAEHIETIKARMYVG---LTPDKRFLPGHLGMGLVEGYDSMGYE--MSKPDLRAELEADLKLICDGKKDKFVVLRQQVQKYKQVFIEAVAKAKKLDEALAQYFGNG--TELAQQEDIYPAMP-----EPIRKCPQCNKD-MVLKTKK-NGGFYLSCMGFPECRSAVWLPDSVLEASRDSSVCPVCQP---HPVYRLKLKFKRGSLPP-------------------TMPLEFVCCIG---------------------------------------------------------------------------------------------------------------------------------GCDDTLREILD---------LRFSGGPPRASQP-------------------------------------SGRLQANQSL--------------------NRMD-NSQH--PQPADSRQTGSSKALAQTLPPPTAAGESNSVTCN-CGQEAVLLTVRKEGPNRGRQFFKCNGGS-CNFFLWADSPNPGAGGPPALAYRPLGAS-------LGCP------PGPG-IHLGGFG----------------NPGDGSGSG-TSCLCSQPSVTRTVQKDGPNKGRQFHTCAKPREQQCGFFQWVDENTAPGTSGAPSWTGDRGRTLESEARSKRPRASSSDMGSTAKKPRKCSLCHQPGHTRPFCPQNR----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "X1WCF3-1", "uniprot_id": "X1WCF3_DANRE", "id": "X1WCF3-1", "name": "DNA topoisomerase", "aln": "-----MNVLFRALRKTVNSRFYRHISVSMIRRTQIKKVLCVAEKNDAAKGIAEIMSNGRSRRREGCSVYNKIYEYEYNLF-----GQNVTVNMTSVSGHLLALEFKAPFQKWHSCSPVLLFDAEVEKYCPENFIPIKRTLEREVRQCQALIVWTDCDREGENIGFEIIDVCK---AVKPNIQVFRARFSEITPNSIRRACETLTEPDINVSDAVDVRQELDLRIGASFTRFQTLRLQKIFP---------------ESLSDQLISYGSCQFPTLGFVVERFKAIQAFIPETFFKIKVVHEPNEEE-SVEFNWKRHRLFNHTACLVLYQMCMEEP--MAKVISVTSKPKSKWRPLPLDTVELEKLASRKLRISAKETMKIAEKLYTQGFISYPRTETNMFPQNLNLTRLVEQQTQ--------DQEWGNFAQRILESGGPTPRN-------GNKSDQAHPPIHPTKYT---NGLQGNEKRLYEFIVRHFLACCSKDAQGQEVTVEIDIAEERFSASGLTIIARNYLEVYPYDKWY-NKVIPSYSPNTTFQPTAIEMVEGQTSPPQLLTEADLISLMEKHGIGTDATHAEHIETIKSRMYVG---LTADQRFLPGELGMGLVEGYNSMGYE--MSKPDLRAELEADLKLVSEGRKNKASVLSYHVAKYKAVFIESVRKAKKLDEALSNYLGPA--QEIAEQEQVELEIP-----LPVRKCPQCNRD-MVLKKKKDSTGMLLSCLGYPACKAAVWFPDTVLEVSRDESICPTCRP---HPVHMLKFKFKRGSLPP-------------------MMPLEFVGCIG---------------------------------------------------------------------------------------------------------------------------------GCDDTLREVLN---------LKYLRGRDAESAP-------------------------------------QANNSSRSSQ--------------------HHIHRTSSAPPPSRVENIRPPAPRPRADPGLQPPPSTQGGAIVCN-CGQDALLLTVRKEGPNQGRQFYKCNTGD-CKFFLWAD--QPPEQGVPERNRGPLSQN-------VQPPRP---SNGFGNVSQQRQN----------------HRGSGGDEGETMCNCNEPSVTRTVMKEGPNKGRMFHTCGKPRDQQCGFFQWANENVAP----ATAFSGGNG----GKPSGNKKASTTSVKPPTAKRQRTCGICHEPGHTRVTCPQAH----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9NG98-1", "uniprot_id": "TOP3A_DROME", "id": "Q9NG98-1", "name": "DNA topoisomerase 3-alpha", "aln": "-----MKAVLTCFR-PVVASHRRYCANPGQA----MKYLNVAEKNDAAKTIAGLLSNGAAQRREGYSVYNKVFDFEAPVR-----GQNAKMVMTSVSGHMMQLAFQVSYKNWRTVDPRSLFDAPVKKGVGSDYEPIKRTLEREVRGCQGLIIWTDCDREGENIGYEIIDVCR---AIKPNISVYRATFSEITTVAVRRALQQLGQPDKRQSDAVDVRTELDLRTGAAITRFQTMRLQRLFP---------------EKIADKLISYGSCQIPTLGFVAERYKEIEAFVSEPFWKIKVLHTIDDL--TVEFNWARNRLFDKEACENYLLLCLAEPDPRALVESVTVKPKHKWRPTPLDTVEMEKLGSRKLKLSAKETMTIAEKLYTKGFISYPRTETNQFSKEFALAPLVEMQTG--------HRDWGAFAQRVIEWG-PNPRN-------GNKSDQAHPPIHPTKLA---ENLQGNEARVYELVVRHFLACVSKDAVGSETLVHIDIAGEKFTANGLVIHERNYLDVYVYDKWS-AKQIHHYENGQRFEPTEVSLHEGATTAPPLLTEADLIALMEKHGIGTDATHAEHINTIKERGYIG---VLDKGFLVPGVIGMGLYEGYDAMELA--LAKPQLRAEFELDLKLICQGQKDPKVVLTEQIAKYKQAYQQITDKITAMDAKISARINETPAANSAVQEGADGSAPSHGIIQSIFQCPKCNEAPLALKPKKNQQGWYIGCNNFPDCKNAVWLPTECKDASVLDECCPTCGDGYRMLKFRLSTPYYRGVFGTPSGWYKTCLPCDNLFRTTFNINLDSVKKVGGIVGEVRGGGGGPGPGPGGGGSGRGAGSGGWSSGPGGGGSGGGGGSGGWGSGTGGGGSGGWGSGTGGGGLGGGKGKKPGGESKKSATKKPPNEPKPKKTKEPKAAPNKKTSSKSSGSIRSFFTSAAPTNSASNGLDEFFDSNDGFEDAMLAAAESVESSSQPKTISMVPLDDDIAAAFAADDDAEFEALVNGGTMPTESNGDQQLDKSLSEWIKEQDKADERPMLWGTRERASLGTAAPTPPPKPAAKRPRWDSVERDSTPPSSVPESETVLCTGCQQPARQNTVRKNGPNLGRLYYKCPKPDECNFFQWADEPPSSAKSKNSTGSAPQSTTSWGSNRVVTLPSIQQSNSQRGQSSMRSNSSSTVTITQTKTKQQERNTATPGDGEEVMCNCGQLASQLTVRKDGPNQGRPFYACP-TREKSCGFFKWGDEDQNQG-----ASSTSWGSANRNPPGRSQPTAITSDGP----KTRRCGLCRKEGHTRNKCPRKDEFDM", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P13099-1", "uniprot_id": "TOP3_YEAST", "id": "P13099-1", "name": "DNA topoisomerase 3", "aln": "-----------------------------------MKVLCVAEKNSIAKAVSQILGGGRSTSRDSGYMYVKNYDFMFSGFPFARNGANCEVTMTSVAGHLTGIDFSHDSHGWGKCAIQELFDAPLNEIMNNNQKKIASNIKREARNADYLMIWTDCDREGEYIGWEIWQEAKRGNRLIQNDQVYRAVFSHLERQHILNAARNPSRLDMKSVHAVGTRIEIDLRAGVTFTRLLTETLRNKLRNQATMTKDGAKHRGGNKNDSQVVSYGTCQFPTLGFVVDRFERIRNFVPEEFWYIQLVVENKDNGGTTTFQWDRGHLFDRLSVLTFYETCIETAGNVAQVVDLKSKPTTKYRPLPLTTVELQKNCARYLRLNAKQSLDAAEKLYQKGFISYPRTETDTFPHAMDLKSLVEKQAQLDQLAAGGRTAWASYAASLLQPENTSNNNKFKFPRSGSHDDKAHPPIHPIVSLGPEANVSPVERRVYEYVARHFLACCSEDAKGQSMTLVLDWAVERFSASGLVVLERNFLDVYPWARWETTKQLPRLEMNALVDIAKAEMKAGTTAPPKPMTESELILLMDTNGIGTDATIAEHIDKIQVRNYVRSEKVGKETYLQPTTLGVSLVHGFEAIGLEDSFAKPFQRREMEQDLKKICEGHASKTDVVKDIVEKYRKYWHKTN-----------------------------------------------------------------------ACKNTLLQVYDRVKASM------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * *****. ** :: ::..* ::. : * ::: * * : ****:**: *. : * . **:* ::: .: * .::**.: .: *::********* **:** . .: : * * ** **.: : * . . * . .**..* *:*** *.::**: * *:. : : .:::***:**:******.:*:: *. *:.* * *:: .: . *:* * :**:: : *: . * * .: **. *:** .* ***::* :* *::.**::: ***** :*:********: *.: : * *** *: *. :* ::: .. .* *.:.*:******* .:. : *:** :.****** *:** *.. : :* * *:* * ** : **:*:** : :* * : . . .: : .: * *:.* :**::** **:.:******* ****:.*: * *: : . : * :*:.* .*:::: ::** * *:* *** :.:*: . *: : **: : : *: :: ..* ", "identical_positions": 200, "similar_positions": 183, "identity": "15.15%" }, { "cls_id": "homologset.agr.MGI:1201374", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4FZU6-1", "uniprot_id": "ANXA8_RAT", "id": "Q4FZU6-1", "name": "Annexin A8", "aln": "MAWWKAWVEQEGV-SVKGSSHFNPDPDAETLYKAMKGIGTNEQAIIDVLTKRSNVQRQQIAKSFKAQFGKDLTETLKSELSGKFERLIVALMYPPYRYEAKELHDAMKGLGTKEGVIIEILASRTKNQLREIMKAYEEDYGSTLEEDIQGDTSGYLERILVCLLQGCRDDVSGFVDPGLALQDAQDLHAAGEKILGTDEMKFITILCTRSATHLMRVFEEYEKIANKSIEDSIKSETHGSLEEAMLTVVKCTRNVHSYFAERLYYAMKGAGTLDGTLIRNIVSRSEIDLNLIKSQFQKMYGKTLSSMIM-GDTSGYYKTALLNLVGTDL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35640-1", "uniprot_id": "ANXA8_MOUSE", "id": "O35640-1", "name": "Annexin A8", "aln": "MAWWKAWVEQEGV-SVKGSSHFNPDPDAETLYKAMKGIGTNEQAIIDVLTKRSNVQRQQIAKSFKAQFGKDLTETLKSELSGKFERLIVALMYPPYSYEAKELHDAMKGLGTKEGVIIEILASRTKNQLREIMKAYEEDYGSTLEEDIQGDTSGYLERILVCLLQGSRDDVSGFVDPGLVLQDAQALHEAGEKIMGTDEMKFITILCTRSATHLMRVFEEYEKIANKCIEDSIKSETHGSLEEAMLTVVKCTRNVHSYFAERLYYAMKGAGTRDGTLIRNIVSRSEIDLNLIKGQFKKMYGKTLSSMIM-ADTSGYYKTALLNLVGTDL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P13928-1", "uniprot_id": "ANXA8_HUMAN", "id": "P13928-1", "name": "Annexin A8", "aln": "MAWWKSWIEQEGV-TVKSSSHFNPDPDAETLYKAMKGIGTNEQAIIDVLTKRSNTQRQQIAKSFKAQFGKDLTETLKSELSGKFERLIVALMYPPYRYEAKELHDAMKGLGTKEGVIIEILASRTKNQLREIMKAYEEDYGSSLEEDIQADTSGYLERILVCLLQGSRDDVSSFVDPGLALQDAQDLYAAGEKIRGTDEMKFITILCTRSATHLLRVFEEYEKIANKSIEDSIKSETHGSLEEAMLTVVKCTQNLHSYFAERLYYAMKGAGTRDGTLIRNIVSRSEIDLNLIKCHFKKMYGKTLSSMIM-EDTSGDYKNALLSLVGSDP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5VT79-1", "uniprot_id": "AXA81_HUMAN", "id": "Q5VT79-1", "name": "Annexin A8-like protein 1", "aln": "MAWWKAWIEQEGV-TVKSSSHFNPDPDAETLYKAMKGIGTNEQAIIDVLTKRSNTQRQQIAKSFKAQFGKDLTETLKSELSGKFERLIVALMYPPYRYEAKELHDAMKGLGTKEGVIIEILASRTKNQLREIMKAYEEDYGSSLEEDIQADTSGYLERILVCLLQGSRDDVSSFVDPALALQDAQDLYAAGEKIRGTDEMKFITILCTRSATHLLRVFEEYEKIANKSIEDSIKSETHGSLEEAMLTVVKCTQNLHSYFAERLYYAMKGAGTRDGTLIRNIVSRSEIDLNLIKCHFKKMYGKTLSSMIM-EDTSGDYKNALLSLVGSDP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P22465-1", "uniprot_id": "ANX10_DROME", "id": "P22465-1", "name": "Annexin B10", "aln": "-------MEYKPVPTVKDAAPFDASQDAQVLRAAMKGFGTDEQEIIDVLVGRSNQQRQTIKAVYEAEFERDLVDDLKDELGGKFEDVIVGLMMPPVEYLCKQLHAAMAGIGTEEATLVEILCTKTNEEMAQIVAVYEERYQRPLAEQMCSETSGFFRRLLTLIVTGVRDGLDTPVDVGQAKEQAAQLYSAGEAKLGTDEEVFNRIMSHASFPQLRLVFEEYKVLSGQTIEQAIKHEMSDELHEAMMAIVECVQSPAAFFANRLYKAMNGAGTDDATLIRIIVSRSEIDLETIKQEFERIYNRTLHSAVVDAETSGDYKRALTALLGSA-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* : * :**.:: *:.. **:.* ****:**:** *****. *** *** * ::*:* :**.: **.**.**** :**.** ** * .*:** ** *:**:*..::***.::*:::: :*: .*** * .* *:: .:***::.*:*. :: * **.:. ** . . ::* *: *** **** * *:. * .:* *****: ::.: **::** * ..*.***:::*:*.:. ::**:*** **:**** *.**** *********: ** .*:::*.:** * :: :*** ** ** *:*: ", "identical_positions": 147, "similar_positions": 100, "identity": "44.68%" }, { "cls_id": "homologset.agr.MGI:1201375", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P50170-1", "uniprot_id": "RDH16_RAT", "id": "P50170-1", "name": "Retinol dehydrogenase 16", "aln": "MWLYLLALVGLWNLLRLFRERKVVSHLQDKYVFITGCDSGFGNLLARQLDRRGMRVLAACLTEKGAEQLRSKTS-DRLETVILDVTKTESIVAATQWVKERVGNTGLWGLVNNAGISGHLGPNEWMNKQNIASVLDVNLLGMIEVTLSTVPLVRKARGRVVNVASIAGRLSF-CGGGYCISKYGVEAFSDSLRRELSYFGVKVAIVEPGFFRTDVTNGVTLSSNFQMLWDQTSSEVREVYGENYLASYLKMLNGLDQRCNKDLSLVTDCMEHALTSCHPRTRYSAGWDAKFFYLPMSYLPTFLVDALFYWTSPKPEKAL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O54909-1", "uniprot_id": "RDH16_MOUSE", "id": "O54909-1", "name": "Retinol dehydrogenase 16", "aln": "MWLYLVALVGLWTLLRFFRVRQVVSHLQDKYVFITGCDSGFGTLLARQLDRRGMRVLAACLTEKGAEELRNKTS-DRLETVILDVTKTESIVTATQWVKEHVGNRGLWGLVNNAGISTPSGPNEWMKKQDFAHVLDVNLLGMIEVTLSMLPLVRKARGRVVNVSSVMGRVSL-FGGGYCISKYGVEAFSDSLRRELSYFGVKVAIIEPGFFLTGVTSSARLCSNTQMLWDQTSSEIREIYGEKYLASYLKRLNKLDKRCNKDLSGVTDCMEHALTACHPRTRYSAGWDAKLFYLPLSYLPTFLVDALLYWTSLKPEKAL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75452-1", "uniprot_id": "RDH16_HUMAN", "id": "O75452-1", "name": "Retinol dehydrogenase 16", "aln": "MWLYLAVFVGLYYLLHWYRERQVLSHLRDKYVFITGCDSGFGKLLARQLDARGLRVLAACLTEKGAEQLRGQTS-DRLETVTLDVTKTESVAAAAQWVKECVRDKGLWGLVNNAGISLPTAPNELLTKQDFVTILDVNLLGVIDVTLSLLPLVRRARGRVVNVSSVMGRVSL-FGGGYCISKYGVEAFSDSLRRELSYFGVKVAMIEPGYFKTAVTSKERFLKSFLEIWDRSSPEVKEAYGEKFVADYKKSAEQMEQKCTQDLSLVTNCMEHALIACHPRTRYSAGWDAKLLYLPMSYMPTFLVDAIMYWVSPSPAKAL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P40471-1", "uniprot_id": "AYR1_YEAST", "id": "P40471-1", "name": "NADPH-dependent 1-acyldihydroxyacetone phosphate reductase", "aln": "--------------------MSELQSQPKKIAVVTGASGGIGYEVTKELARNGYLVYACARRLEPMAQLAIQFGNDSIKPYKLDISKPEEIVTFSGFLRANLPDGKLDLLYNNAGQSCT-FPALDATDAAVEQCFKVNVFGHINMCRELSEFLIKAKGTIVFTGSLAGVVSFPFGSIYSASKAAIHQYARGLHLEMKPFNVRVINAITGGVATDIADKRPLPETSIYNFPE-GREAFNSRKTMAKDNKPMPADAYAKQLVKDILSTSDPVDVYRGTFANIMRFVMIFVP-YWLLEKGLSKKFKLDKVNNALKSKQKNKDD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :. .* ..:**...*:* ::::* .* * *.. : :* : . * ::. **::*.*.:.: : ::: : : * * **** * * .. . :.**::* *:: . :: :*:* :* ..*: * :*: *. *. ** .:. :: .*: *:. *.*:* .* . * ::. : .. : . . * : . : :: :*: .:: :: : *: : . * . .* :* : . . : ", "identical_positions": 50, "similar_positions": 105, "identity": "15.62%" }, { "cls_id": "homologset.agr.MGI:1201378", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P12429-1", "uniprot_id": "ANXA3_HUMAN", "id": "P12429-1", "name": "Annexin A3", "aln": "-MASIWV-----------------GHRGTVRDYPDFSPSVDAEAIQKAIRGIGTDEKMLISILTERSNAQRQLIVKEYQAAYGKELKDDLKGDLSGHFEHLMVALVTPPAVFDAKQLKKSMKGAGTNEDALIEILTTRTSRQMKDISQAYYTVYKKSLGDDISSETSGDFRKALLTLADGRRDESLKVDEHLAKQDAQILYKAGENRWGTDEDKFTEILCLRSFPQLKLTFDEYRNISQKDIVDSIKGELSGHFEDLLLAIVNCVRNTPAFLAERLHRALKGIGTDEFTLNRIMVSRSEIDLLDIRTEFKKHYGYSLYSAIKSDTSGDYEITLLKICGGDD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O35639-1", "uniprot_id": "ANXA3_MOUSE", "id": "O35639-1", "name": "Annexin A3", "aln": "-MASIWV-----------------GPRGTIKDYPGFSPSVDAEAIRKAIRGLGTDEKTLINILTERSNAQRQLIVKQYQAAYEQELKDDLKGDLSGHFEHVMVALVTAPALFDAKQLKKSMKGTGTDEDALIEILTTRSSRQMKEISQAYYTVYKKSLGDDISSETSGDFRKALLTLADGRRDESLKVDEHLAKKDAQILYNAGENKWGTDEDKFTEVLCLRSFPQLKLTFDEYRNISQKDIEDSIKGELSGHFEDLLLAIVHCARNTPAFLAERLHQALKGAGTDEFTLNRIMVSRSEIDLLDIRHEFKKHYGYSLYSAIQSDTSGDYRTVLLKICGEDD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P14669-1", "uniprot_id": "ANXA3_RAT", "id": "P14669-1", "name": "Annexin A3", "aln": "MAASLWV-----------------GPRGTINNYPGFNPSVDAEAIRKAIKGIGTDEKTLINILTERSNAQRQLIVKQYQEAYEQALKADLKGDLSGHFEHVMVALITAPAVFDAKQLKKSMRGMGTDEDTLIEILTTRTSRQMKEISQAYYTAYKKNLRDDISSETSGDFRKALLTLADGGRDESLKVDEHLAKKDAQTLYDAGEKKWGTDEDKFTEILCLRSFPQLKLTFDEYRNISQKDIEDSIKGELSGHFEDLLLAVVRCTRNTPAFLAGRLHQALKGAGTDEFTLNRIMVSRSEIDLLDIRREFKKHYGCSLYSAIQSDTSGDYRTVLLKICGGDD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M1N272-1", "uniprot_id": "A0A8M1N272_DANRE", "id": "A0A8M1N272-1", "name": "Annexin", "aln": "-MADLWEELQSVANAAPASFAAAPGERGTIKAKANFNVSEDVAALRKAIEGVGTNEKTLIEILTHRSSSQKQEIAKAYRETTKRILANDLKGETHGNFEKVLVGLARPLAVNDAEWLHEALKGAGTDNNILIEILSSRTNKQIKELSAAYAEETKKTLTQALKTEVSGHYGKAIILLAEGARDENPSVNVDKAREDAQALYQAGEKKLGTDESKFIEILCKRSFPQLRQTILEYKNFSKNTLQKSIEKEMSGNLEELLVSIVKCAISTPAYFAEKLNKSMKGAGTDETTLTRVMVSRGEVDMLDIRAEYKTLYKSSLYKAISSDVSGDYADCLKMICGGDD", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.:* * ***:. ..*. * *. *::***.*:**:** **.***.**.:*:* *.* *: : : * ****: *:**:::*.* . *: **: *:::::* **::: *****::*:.:*:*::* ** **.* : :.:*.**.: **:: **:* ***. .*: . *::*** **.***:: ****.** *:** ******: *: **:*:*:: : .**: *:**::*:**:::*.*. .***::* :*::::** **** **.*:****.*:*:**** *:*. * ***.**.**.**** * *** **", "identical_positions": 156, "similar_positions": 105, "identity": "45.75%" }, { "cls_id": "homologset.agr.MGI:1201386", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P47245-1", "uniprot_id": "NRDC_RAT", "id": "P47245-1", "name": "Nardilysin", "aln": "MLRRVAVAAVFATGRKLRCEAGRDVTAVGRIEARGLCEE--SAKPFPTLTMPGRNKAKSTCSCPDLQPNGQDLGESGRVARLGADESEEEGR--SLSNVGDPEIIKSPSDPKQYRYIKLQNGLQALLISDLSNVEGKTGNATDEEEEEEEEEEEGEEEEEEEEDDDDDDDEDSGAEIQDDDEEGFDDEEEFDDD---EHDDDDLDNEENELEELEERVEARKKT-TEKQSAAALCVGVGSFADPDDLPGLAHFLEHMVFMGSLKYPDENGFDAFLKKHGGSDNASTDCERTVFQFDVQRKYFKEALDRWAQFFIHPLMIRDAIDREVEAVDSEYQLARPSDANRKEMLFGSLARPGHPMGKFFWGNAETLKHEPKKNNIDTHARLREFWMRYYSAHYMTLVVQSKETLDTLEKWVTEIFSQIPNNGLPKPNFS--HLTDPFDTPAFNKLYRVVPIRKIHALTITWALPPQQQHYRVKPLHYISWLVGHEGKGSILSYLRKKCWALALFGGNGETGFEQNSTYSVFSISITLTDEGYEHFYEVAHTVFQYLKMLQKLGPEKRVFEEIQKIEDNEFHYQEQTDPVEYVENMCENMQLYPRQDFLTGDQLLFEYKPE----VIAEALNQLVPQKANLVLLSG---ANEGRCDLKEKWFGTQYSIEDIENSWTELWKSNFDLNSDLHLPAENKYIATDFTLKAFDCP---ETEYPAKIVNTPQGCLWYKKDNKFKIPKAYIRFHLISPLIQKSAANVVLFDIFVNILTHNLAEPAYEADVAQLEYKLVAGEHGLIIRVKGFNHKLPLLFQLIIDYLTEFSS--TPAVFTMITEQLKKTYFNILIKPETLAKDVRLLILEYSRWSMIDKYRALMDGLSLESLLNFVKDFKSQLFVEGLVQGNVTSTESMDFLRYVVDKLNFVPL-EREMPVQFQVVELPSGHHLCKVRALNKGDANSEVTVYYQSGTRSLREYTLMELLVMHMEEPCFDFLRTKQTLGYHVYPTCRNTSGILGFSVTVGTQATKYNSETVDKKIEEFLSSFEEKIENLTEDAFNTQVTALIKLKECEDTHLGEEVDRNWNEVVTQQYLFDRLAHEIEALKSFSKSDLVSWFKAHRGPGSKMLSVHVVGYGK--------YELEEDGAPVCEDPNS-------REGMQLIYLPPSPLLAE--------------------------------STTPITDIRAFTATLSLFPYHKIVK------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BHG1-1", "uniprot_id": "NRDC_MOUSE", "id": "Q8BHG1-1", "name": "Nardilysin", "aln": "MLRRVAVAAVCVTGRKLRCEAGRELTALGRIEARGLCEE--SSKPFPTLTMPGRNKAKSTCSCPDLQPNGQDLGESGRLARLGADESEEEGR--SFSNVGDPEIIKSPSDPKQYRYIKLQNGLQALLISDLSNVEGKTGNATDEEEEEEEEEEE---EDDDDDDDDDDDDEDSGAEIQDDDEEGFDDEEEFDDDDDDEHDDDDLENEENELEELEERVEARKKT-TEKQSAAALCVGVGSFADPDDLPGLAHFLEHMVFMGSLKYPDENGFDAFLKKHGGSDNASTDCERTVFQFDVQRKYFKEALDRWAQFFIHPLMIRDAIDREVEAVDSEYQLARPSDANRKEMLFGSLARPGHPMGKFFWGNAETLKHEPKKNNIDTHARLREFWMRYYSAHYMTLVVQSKETLDTLEKWVTEIFSQIPNNGLPKPNFS--HLTDPFDTPAFNKLYRVVPIRKIHALTITWALPPQQQHYRVKPLHYISWLVGHEGKGSILSYLRKKCWALALFGGNGETGFEQNSTYSVFSISITLTDEGYEHFYEVAHTVFQYLKMLQKLGPEKRVFEEIQKIEDNEFHYQEQTDPVEYVENMCENMQLYPRQDFLTGDQLLFEYKPE----VIAEALNQLVPQKANLVLLSG---ANEGRCDLKEKWFGTQYSIEDIENSWTELWKSNFDLNPDLHLPAENKYIATDFTLKAFDCP---ETEYPAKIVNTAQGCLWYKKDNKFKIPKAYIRFHLISPLIQKSAANVVLFDIFVNILTHNLAEPAYEADVAQLEYKLVAGEHGLIIRVKGFNHKLPLLFQLIIDYLTEFSS--TPAVFTMITEQLKKTYFNILIKPETLAKDVRLLILEYSRWSMIDKYQALMDGLSLDSLLNFVKDFKSQLFVEGLVQGNVTSTESMDFLKYVVDKLNFAPL-EREMPVQFQVVELPSGHHLCKVRALNKGDANSEVTVYYQSGTRSLREYTLMELLVMHMEEPCFDFLRTKQTLGYHVYPTCRNTSGILGFSVTVGTQATKYNSETVDKKIEEFLSSFEEKIENLTEDAFNTQVTALIKLKECEDTHLGEEVDRNWNEVVTQQYLFDRLAHEIEALKSFSKSDLVSWFKAHRGPGSKMLSVHVVGYGK--------YELEEDGAPFGEDSNS-------REGMQLTYLPPSPVLAE--------------------------------STTPITDIRAFTATLSLFPYHKIVK------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43847-1", "uniprot_id": "NRDC_HUMAN", "id": "O43847-1", "name": "Nardilysin", "aln": "MLRRVTVAAVCATRRKL-CEAGRELAALWGIETRGRCEDSAAARPFPILAMPGRNKAKSTCSCPDLQPNGQDLGENSRVARLGADESEEEGRRGSLSNAGDPEIVKSPSDPKQYRYIKLQNGLQALLISDLSNMEGKTGNTTDDEEEEEVEEEE------------EDDDEDSGAEIEDDDEEGFDDEDEFDDE-----HDDDLDTEDNELEELEERAEARKKT-TEKQSAAALCVGVGSFADPDDLPGLAHFLEHMVFMGSLKYPDENGFDAFLKKHGGSDNASTDCERTVFQFDVQRKYFKEALDRWAQFFIHPLMIRDAIDREVEAVDSEYQLARPSDANRKEMLFGSLARPGHPMGKFFWGNAETLKHEPRKNNIDTHARLREFWMRYYSSHYMTLVVQSKETLDTLEKWVTEIFSQIPNNGLPRPNFG--HLTDPFDTPAFNKLYRVVPIRKIHALTITWALPPQQQHYRVKPLHYISWLVGHEGKGSILSFLRKKCWALALFGGNGETGFEQNSTYSVFSISITLTDEGYEHFYEVAYTVFQYLKMLQKLGPEKRIFEEIRKIEDNEFHYQEQTDPVEYVENMCENMQLYPLQDILTGDQLLFEYKPE----VIGEALNQLVPQKANLVLLSG---ANEGKCDLKEKWFGTQYSIEDIENSWAELWNSNFELNPDLHLPAENKYIATDFTLKAFDCP---ETEYPVKIVNTPQGCLWYKKDNKFKIPKAYIRFHLISPLIQKSAANVVLFDIFVNILTHNLAEPAYEADVAQLEYKLVAGEHGLIIRVKGFNHKLPLLFQLIIDYLAEFNS--TPAVFTMITEQLKKTYFNILIKPETLAKDVRLLILEYARWSMIDKYQALMDGLSLESLLSFVKEFKSQLFVEGLVQGNVTSTESMDFLKYVVDKLNFKPL-EQEMPVQFQVVELPSGHHLCKVKALNKGDANSEVTVYYQSGTRSLREYTLMELLVMHMEEPCFDFLRTKQTLGYHVYPTCRNTSGILGFSVTVGTQATKYNSEVVDKKIEEFLSSFEEKIENLTEEAFNTQVTALIKLKECEDTHLGEEVDRNWNEVVTQQYLFDRLAHEIEALKSFSKSDLVNWFKAHRGPGSKMLSVHVVGYGK--------YELEEDGTPSSEDSNSS------CEVMQLTYLPTSPLLAD--------------------------------CIIPITDIRAFTTTLNLLPYHKIVK------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0S6B9-1", "uniprot_id": "B0S6B9_DANRE", "id": "B0S6B9-1", "name": "", "aln": "--------------------------------------------------MPQTNKFKCAAASSPAQSAGPDRGEP--VRDPNAPPGDSGGD----ENQGDPQIIKSPSDPKQYRYIELSNGLRALLISDLSGLDGKAE----DEDDEDSEEEE-------------AEEEAEGEEEEGDSGEGTDEESEEEGD-----------SQDSDFEELDEESDQKKKKGSEKQSAAALCIGVGSFSDPNDLPGLAHFLEHMVFMGSEKYPSENGFDAFLKKHGGSDNASTDCERTIFQFDVQRKRFKEALDRWAQFFICPLMIEDAIDREVEAVDSEYQLAKPSDSHRKEMLFGSLAKPDHPMSKFCWGNAQTLKTEPKEKNINVYKRLREFWKRHYSAHYMTLAVQSKESLDTLEEWVREIFSQVPNNGQLKPDFS--DKLNPFETPAFNKLYRVVPVRKVHALTITWALPPQEKHYRVKPLHYIAWLIGHEGTGSILSMLRRKCWALALFGGNSETGFDQNTTYSIFSISITLTDEGFQNFYEVAHLVFQYLKMLQTLGPQQRIYEEIQKIEANEFHYQEQTDPIEYVEDICENMQLFPKEDFLTGDQLMFEFKPE----VISAALNLLTPEKANLLLLSP---EHEGQCPLREKWFGTQYSTEDIEQHWREIWAKDFDLNPSLHLPAENKFIATDFALKTSDCP---DTEYPVRIMNNDRGCLWYKKDNKFKIPKAYVRFHLISPVVQKSPKNLVLFDLFVNILVHNLAEPAYEADVAQLEYKLVAGEHGLVIKVKGFNHKLPLLFNLIVDYLADFSA--APDVFSMFAEQLKKTYFNILIKPEKLGKDVRLLILEHSRWSTIQKYQAVLDGLSVDELMEFVSGFKSELYAEGLLQGNVTSTESMGFLQYVTEKLQFKKL-SVEVPVLFRVVELPQKHHLCKVKSLNKGDANSEVTVYYQSGPKNLREHTLMELLVMHMEEPCFDFLRTKETLGYHVYPTCRNTSGVLGFSVTVETQATKFNTELVETKIEEFLVSFGEKMNSLSDDAFRTQVTALVKLKGCEDTHLGEEVDRNWTEVVTQQYVFDRLSREIDALKLMTKAELVNWFMEHRGEGNRKLSVHVVGYGV--------EENDPPNDPHPGEEEEASKMSLYGEVSKLTFLQASNLLAS--------------------------------VST-ITDIRAFTQTLNLFPYHKILK------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q1L985-1", "uniprot_id": "Q1L985_DANRE", "id": "Q1L985-1", "name": "", "aln": "--------------------------------------------------MPQMSKAKSCGCNVTCEVSGPDSGEPPPAVTEPQESDAADSN----------TIIKSPNDYKTYRYIELSNGLKALLISDVSSQS-------------------------------------------ESCRESVDKEVEEEGD----------RGSASDISKHSERGKQSCRS--EKQSAAALCISVGSFSDPADLPGLAHFLEHMVFMGSEKYPVENGFDAFLKKHGGSDNASTDCERTIFQFDVQRKYLREALDRWAQFFICPLMIPDAVDREVEAVDSEYQMAQPLDSNRKEMLFGSLAKAGHPMSKFFWGNAQTLKQEPREKKINTYERLRDFWRRYYSAQYMTLAVQSKETLDTLEEWVREIFVQIPNNGLPKADFS--DLQDPFDTPDFCKLYRVVPVQKVHALTISWALPPQAKHYRVKPLHYISWLIGHEGVGSVLSLLRKRCWALSLFGGNSESGFDQNSTYSIFSISITLSDEGLQNFLQVIHIIFQYLKMLQSVGPQQRIYEEIQKIEANEFHYQEQTEPIEFVANMSENMQLFPKEHFLCGDQLMFDFNPEASHCVISAALSLLTPGKANILLLSP---QHDGLCPLKEKWFGTQYSVEDIPQEFRDLWAGDFPLHPELQLPAENKFIATDFTLRTSDCP---DTDFPVKIIDNERGRLWFRKDNKFKIPKAYARFQLLTPFIQESPKNLVLFDLFVNIVAHNLAELAYDAEVAQLQYNLLPGDHGLFIRLKGFNHKLPLLLKLIVDHLADFSA--TPDVFNMFIEQLKKTYYIILIRPERLGKDVRLQILEHHRWSVMQKYEAIMADPSVADLMTFANRFKAELFVEGLVQGNFTSAESKEFLQCFIEKLKYAPH-PIEPPVLFRVVELPQTHHLCKVQSLNKADANSEVTVYYQTGLKNLREHTLMELLVMHMEEPCFDFLRTKETLGYQVYPICRNTSGILGFSVTVETQATKFSTDFVEGKIEAFLVSFGEKLVQLSDEAFGAQVTALIKLKECEDTQLGDEVDRNWFEVVTQQYVFDRLNKEIEILKDVTKDELVSFYMEHRKENSRKLSIHVVGFGE--------EEKEIHGEDQCSSNPETSS---YANISKLTFLS-AAAMKE--------------------------------KSTMITDIRAFTSSLHLHPYHKILI------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VP94-1", "uniprot_id": "Q9VP94_DROME", "id": "Q9VP94-1", "name": "", "aln": "----------------------------------------------------MCFRPRLGLRRITKQVQKWLNRQQYPMSTASVVVQYHEEP------------DKSDGDSKLYRALTLSNGLRAMLISD---------------------------------------------------------SYIDEP---------------SIHRASRESLNSSTENFNGKLAACAVLVGVGSFSEPQQYQGLAHFVEHMIFMGSEKFPVENEFDSFVTKSGGFSNAHTENEETCFYFELDQTHLDRGMDLFMNLMKAPLMLPDAMSRERSAVQSEFEQTHMRDEVRRDQILASLASEGYPHGTFSWGNYKTLKEG--VDDSSLHKELHKFYRDHYGSNRMVVALQAQLSLDELEELLVRHCADIPTSQQNSIDVSQLNYQKAFRDQFYKDVFLVQPVEDVCKLELTWVLPPMKNFYRSKPDMFISQLIGYEGVGSLCAYLRHHLWCISVVAGVAESSFDSNSIYSLFNICIYLSDDGFDHIDEVLEATFAWVKLIINSDQLQDSYKESQQIENNNFRFQIEPPPIDHVQSIVESFNYLPSKDVLTGPQLYFQYEES----AIELLRQHMNKFNFNIMISSYIPYEKN-EYDQREPWFGTQFKTISMPPKWQTMWEQSATIK-ELHYPQPNPFVTTDFKIHWVESGKPHVSRSPKALIRNDLCELWFRQDNIFKLPDGYINLYFITPLVRESVKQYMLGVLFTYLVEFRMAEQLYPALEAGLTYGLYIGDKGLVMRVSGYNEKLPLLVEIILN-MMQTIE-LDIGQVNAFKDLKKRQIYNALINGKSLNLDLRLSILENKRFSMISKYESVDD-ITMDDIKSFKENFHKKMYVKGLIQGNFTEDQATDLMQKVLDTYKSEKLDNLS-ALDNHLLQIPLGSYYLRAKTLNEDDSNTIITNYYQIGPSDLKMECIMDLVELIVEEPFFNQLRTQEQLGYSLGIHQRIGYGVLAFLITINTQETKHRADYVEQRIEAFRSRMAELVSQMSDTEFKNIRETLINGKKLGDTSLDEEVLRNWSEIVTKEYFFNRIETQIQMLSHLTKEDVLNFLNDNDKNNLRKLSVQVVGN----------HNQTSNSTAQASRSGSLSDLLDDVQDNMANETDSAKPMTDKIRLEFLGESDD---------------------PSSIKDIYAFKKDLYVFPLFNTNPNLANKS------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VYT3-1", "uniprot_id": "Q9VYT3_DROME", "id": "Q9VYT3-1", "name": "", "aln": "---------------------------------------MLWQRYSAHLFRRFEFHVRTKRRSPITQLAGVRAITYSSLCKMTDQVKYLDIP------------DKSETDKKLYKTLLLGNGLHALIVSDPSPMPHDGF--------------------------------TTSESSSSKSTVSTSSSIISRSE-----------STSSTSTDSESSEESSSEEGDEKLAACALLIDYGSFAEPTKYQGLAHFLEHMIFMGSEKYPKENIFDAHIKKCGGFANANTDCEDTLFYFEVAEKHLDSSLDYFTALMKAPLMKQEAMQRERSAVDSEFQQILQDDETRRDQLLASLATKGFPHGTFAWGNMKSLKEN--VDDAELHKILHEIRKEHYGANRMYVCLQARLPIDELESLVVRHFSGIPHNEVKAPDLSSFNYKDAFKAEFHEQVFFVKPVENETKLELTWVLPNVRQYYRSKPDQFLSYLLGYEGRGSLCAYLRRRLWALQLIAGIDENGFDMNSMYSLFNICIYLTDEGFKNLDEVLAATFAYVKLFANCGSMKDVYEEQQRNEETGFRFHAQRPAFDNVQELVLNLKYFPPKDILTGKELYYEYNEE----HLKELISHLNEMKFNLMVTSRRKYDDISAYDKTEEWFGTEYATIPMPEKWRKLWEDSVPLP-ELFLPESNKYVTDDFTLHWHSMGRPEVPDSPKLLIKTDTCELWFRQDDKFDLPEAHMAFYFISPMQRQNAKNDAMCSLYEEMVRFHVCEELYPAISAGLSYSLSTIEKGLLLKVCGYNEKLHLIVEAIAEGMLNVAETLDENMLSAFVKNQRKAFFNALIKPKALNRDIRLCVLERIRWLMINKYKCLSS-VILEDMREFAHQFPKELYIQSLIQGNYTEESAHNVMNSLLSRLNCKQIRERGRFLEDITVKLPVGTSIIRCHALNVQDTNTVITNFYQIGPNTVRVESILDLLMMFVDEPLFDQLRTKEQLGYHVGATVRLNYGIAGYSIMVNSQETKTTADYVEGRIEVFRAKMLQILRHLPQDEYEHTRDSLIKLKLVADLALSTEMSRNWDEIINESYLFDRRRRQIEVLRTLQKDEIINFVISIDGDNMRKLSVQVIGHRPAGMPEPLCGEDTAKCASKSDDESESENDDDDDEDEEEEESSEEEEEEEKEKEGLKGEDEDDLFYSLENKLNIVFLPAKFNNAFIITDIEKFKDDQYVYPQQKTQPKEEDELISAHIADAIRQV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : ** * * *: : * ***:*:::** . . . . . * :*.*: :. ***::* . *****:***:**** *:* ** **:.:.* ** ** *: * * * *:: .. : .:* : :: *** :*:.** .**:**:: * *:: ::.*** ..* ..* *** ::** .. . : *:.: :*.:: * : :*:: .:* **. : . :* . :.. . ..* . .:: * *:.. * ::*.** :.** ** ::: *:*:** **: : **:: *.: :..* *..*: *: **:*.*.* *:*:* .:: :* * ::*:: . . : ::* :: * . *::: : ..: * .: .:: * :..* * :* :::: . : . : : *::: * . * ****:: : : :* . : .* * * ::: ** :: . . * :: . **:::*: *.:*..: : :::*. ::. : : :: :: ..:.* * * * * * * ::**.::: *:*.** *:.: * : : : .. : . :: : **. : * *:** :** *: :.**..: : .: * * ::: :.*:*** *. .: .:. . . : : :::* : ::** *:*: :* :** * :: :::*: : ::** *: ***:: *** : * *: .: : : :* ** :: *: :** * : : : :.: : :*:: * * *. *: *** *::.:.*.*:* :*: * . * :::.: . : **::*:* : . : . *.** *. : * : ", "identical_positions": 226, "similar_positions": 334, "identity": "18.09%" }, { "cls_id": "homologset.agr.MGI:1201387", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O54949-1", "uniprot_id": "NLK_MOUSE", "id": "O54949-1", "name": "Serine/threonine-protein kinase NLK", "aln": "MSLCGTRAN--AKMMAAYNGGTSAAAAGHHHHHHHHLPHLPPP-HLHHHHHP-QHHL-HPGSAAAVHPVQQHTSSAAAAAAAAAAAAAMLNPGQQQPYFPSPAPGQAPGP-AAAAPAQVQAAAAATVKAHHH--QHSHHPQQQLDIEPDRPIGYGAFGVVWSVTDP--RDGKRVALKKMPNVFQNLVSCKRVFRELKMLCFFKHDNVLSALDILQPPHIDYFEEIYVVTELMQSDLHKIIVSPQPLSSDHVKVFLYQILRGLKYLHSAGILHRDIKPGNLLVNSNCVLKICDFGLARVEEL-------DESRHMTQEVVTQYYRAPEILMGSRHYSNAIDIWSVGCIFAELLGRRILFQAQSPIQQLDLITDLLGTPSLEAMRTACEGAKAHILRGPHKQPSLPVLYT-LSSQATHEAVHLLCRMLVFDPSKRISAKDALAHPYLDEGRLRYHTCMCKCCFSTSTG-RVYTSDFEPVTNPKFDDTFEKNLSSVRQVKEIIHQFILEQQKGNRVPLCINPQSAAFKSFISSTVAQPSEMPPSPLVWE---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZSZ3-1", "uniprot_id": "NLK_RAT", "id": "D3ZSZ3-1", "name": "Serine/threonine-protein kinase NLK", "aln": "MSLCGTRAN--AKMMAAYNGGTSAAAAGHHHHHHHHLPHLPPP-HLHHHHHP-QHHL-HPGSAAAVHPVQQHTSSAAAAAAAAAAAAAMLNPGQQQPYFPSPAPGQAPGP-AAAAPAQVQAAAAATVKAHHH--QHSHHPQQQLDIEPDRPIGYGAFGVVWSVTDP--RDGKRVALKKMPNVFQNLVSCKRVFRELKMLCFFKHDNVLSALDILQPPHIDYFEEIYVVTELMQSDLHKIIVSPQPLSSDHVKVFLYQILRGLKYLHSAGILHRDIKPGNLLVNSNCVLKICDFGLARVEEL-------DESRHMTQEVVTQYYRAPEILMGSRHYSNAIDIWSVGCIFAELLGRRILFQAQSPIQQLDLITDLLGTPSLEAMRTACEGAKAHILRGPHKQPSLPVLYT-LSSQATHEAVHLLCRMLVFDPSKRISAKDALAHPYLDEGRLRYHTCMCKCCFSTSTG-RVYTSDFEPVTNPKFDDTFEKNLSSVRQVKEIIHQFILEQQKGNRVPLCINPQSAAFKSFISSTVAQPSEMPPSPLVWE---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UBE8-1", "uniprot_id": "NLK_HUMAN", "id": "Q9UBE8-1", "name": "Serine/threonine-protein kinase NLK", "aln": "MSLCGARAN--AKMMAAYNGGTSAAAAGHHHHHHHHLPHLPPP-HLHHHHHP-QHHL-HPGSAAAVHPVQQHTSSAAAAAAAAAAAAAMLNPGQQQPYFPSPAPGQAPGP-AAAAPAQVQAAAAATVKAHHH--QHSHHPQQQLDIEPDRPIGYGAFGVVWSVTDP--RDGKRVALKKMPNVFQNLVSCKRVFRELKMLCFFKHDNVLSALDILQPPHIDYFEEIYVVTELMQSDLHKIIVSPQPLSSDHVKVFLYQILRGLKYLHSAGILHRDIKPGNLLVNSNCVLKICDFGLARVEEL-------DESRHMTQEVVTQYYRAPEILMGSRHYSNAIDIWSVGCIFAELLGRRILFQAQSPIQQLDLITDLLGTPSLEAMRTACEGAKAHILRGPHKQPSLPVLYT-LSSQATHEAVHLLCRMLVFDPSKRISAKDALAHPYLDEGRLRYHTCMCKCCFSTSTG-RVYTSDFEPVTNPKFDDTFEKNLSSVRQVKEIIHQFILEQQKGNRVPLCINPQSAAFKSFISSTVAQPSEMPPSPLVWE---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F1L8-1", "uniprot_id": "E7F1L8_DANRE", "id": "E7F1L8-1", "name": "Mitogen-activated protein kinase", "aln": "MALCGTTASNAAKMMAAYNGGTAAVAA-HHPHHHHQLPHLPPPAHLHHHHHAGQHHLQHPGSAAAVHPVQQHAS-TAAAAAAAAAAAVMLNPSQQQPYFPSPAPGQAPGPAAAAAPAQVQAAAAAAVKVHHHHHQHSHHLQQQLDIEPDRPIGYGAFGVVWSVTDP--RDGKRVALKKMPNVFQNLVSCKRVFRELKMLCFFKHDNVLSALDILQPPHIDYFEEIYVVTELMQSDLHKIIVSPQPLSSDHVKVFLYQILRGLKYLHSAGILHRDIKPGNLLVNSNCVLKICDFGLARVEEL-------DESRHMTQEVVTQYYRAPEILMGSRHYSNAIDIWSVGCIFAELLGRRILFQAQSPIQQLDLITDLLGTPSLEAMRTACEGARAHILRGPHKQPSLPVLYT-LSSQATHEAVHLLCRMLVFDPSKRISAKDALAHPYLDEGRLRYHTCMCKCCYTTSSG-RVYTSDFEPVTNPKFDDGFEKNLTSVRQVKEIIHQFILEQQKGNRVPLCINPQSAAFKSFISSTVAQPSEMPPSPLVWE---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A4D6K823-1", "uniprot_id": "A0A4D6K823_DROME", "id": "A0A4D6K823-1", "name": "Mitogen-activated protein kinase", "aln": "MSVS----------MSLVQGG--------------------------------------------------------AAGGAPQGASAILAAA--APYYQPPAVPQ--------------------------------------DVQPDRPIGYGAFGVVWAVTDP--RDGRRVALKKLPNVFQSLVSSKRVFRELKMLCFFKHENVLSALDILQPPHLDFFQEIYVITELLQSDLHKIIVSPQHLSADHIKVFLYQILRGLKYLHSARILHRDIKPGNLLVNSNCVLKICDFGLARVEEP-------DQAKHMTQEVVTQYYRAPEILMGARHYSSAVDVWSVGCIFGELLGRRILFQAQNPVQQLELITELLGTPTMEDMRHACEGARTHMLRRAPKPPSFSVLYT-LSSHATHEAVHLLCQMLVFDPDKRISVTDALAHPYLDEGRLRYHSCMCKCCFTTSAGMRQYTADFEPSAGQPFDDLWERKLTSVQQVKEEMHKFIAEQLQTGRVPLCINPQSAAFKSFASSTVAHPSELPPSPHQWEXRQNEAIAA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P41808-1", "uniprot_id": "SMK1_YEAST", "id": "P41808-1", "name": "Sporulation-specific mitogen-activated protein kinase SMK1", "aln": "------------------------------------------------------------------------MNCTLTDNTRAINVASNLGAPQQRTIFAKERISIPG------------------------------------YYEIIQFLGKGAYGTVCSVKFKGRSPAARIAVKKISNIFNKEILLKRAIRELKFMNFFKGHKNIVNLIDLEIVTSSPYDGLYCYQELIDYDLAKVIHSSVQLSEFHIKYFLYQILCGLKYIHSADVIHRDLKPGNILCTLNGCLKICDFGLARGIHAGFFKCHSTVQPHITNYVATRWYRAPELLLSNQPYSKSVDIWAVGCILAEFYARKPVFMGRDSMHQIFEIIKVLGTPDKDILIKFGTIKAWNLGKNSNNPVYKKIPWSNIFPFASHEAINLIESLLHWDSTHRLNVEQAISHPFLNEVRK--------------------PDDEPVCLQGPFDFTYESELNSMSKLRDYLVEEVKN-----------------FKTDLSSSSL----------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . .: * . . : : : :* **:*.* :*. . *:*:**:.*:*:. : **.:****:: *** .: : * *: . :: :* **:: ** *:* *. ** *:* ****** ****:*** ::***:****:* . * ********** . *:*: *.*::*****:*:. : **.::*:*:****:.*: .*: :* .:..::*: * .:**** : : :: : . : : :: : . *:***::*: :* :*. :*:.. :*::**:*:* * . * ** :* :*.*: :::: : : : : **: **: ", "identical_positions": 119, "similar_positions": 119, "identity": "21.44%" }, { "cls_id": "homologset.agr.MGI:1201400", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M107-1", "uniprot_id": "F1M107_RAT", "id": "F1M107-1", "name": "SH3 and cysteine-rich domain-containing protein", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MIPPSGAREDSGDG-----------------------------------------LTREATGTEQPPSPASTSSLESKLQKLKRSLSFKTKSLRSK---------SADNFFPRTNS-DVKPQADLLAKAS----------------------PGPSPIP-----------IPGSP---ASMPTKAGLHPGSNSKVHAFQEHVFKKPTFCDVCNHMIVG----------THAKHGLRCGACKMSIHHKCADGLAPQRCMGKLPKGFR---------------------------------RYYSSPLLIHEQFG---------------------------------------CIKEVMPIACGNKVDP-VYEALRFGTSLAQR------------TKKSSSGSGSDSPPRT-----STSELVEVPEEADGPGD-----------------------------SSDIRPRSNSVFTYPEN-----------------GTDDFRDQVKTINHQGP-------LSKDPLQMNTYVALYRFIPQENEDLEMRPGDMITLLEDSNEDWWKGKIQDRVGFFPANFVQRVEEHEKIYRCVRTFIGCKDQG--QITLKENQICVTSEEERDGFIRVLSGKK-RGLVPLDVLVDV------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97306-1", "uniprot_id": "STAC_MOUSE", "id": "P97306-1", "name": "SH3 and cysteine-rich domain-containing protein", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MIPPSGAREDSGDG-----------------------------------------LTGEATGTEQPPSPASTSSLESKLQKLKRSLSFKTKSLRSK---------SADNFFPRTNS-DVKPQADLLAKAS----------------------PGPSPIA-----------IPGSP---ASMPTKAGLHPGSNSKLHAFQEHVFKKPTFCDVCNHMIVG----------THAKHGLRCGACKMSIHHKCADGLAPQRCMGKLPKGFR---------------------------------RYYSSPLLIHEQFG---------------------------------------CIKEVMPIACGNKVDP-VYEALRFGTSLAQR------------TKKGGSGSGSDSPPRT-----STSELVDVPEEADGPGD-----------------------------GSDMRTRSNSVFTYPEN-----------------GMDDFRDQMKTTNHQGP-------LSKDPLQMNTYVALYRFIPQENEDLEMRPGDMITLLEDSNEDWWKGKIQDRVGFFPANFVQRVEEHEKIYRCVRTFIGCKDQG--QITLKENQICVTSEEEQDGFIRVLSGKK-RGLVPLDVLVDV------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99469-1", "uniprot_id": "STAC_HUMAN", "id": "Q99469-1", "name": "SH3 and cysteine-rich domain-containing protein", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MIPPSSPREDGVDG-----------------------------------------LPKEAVGAEQPPSPASTSSQESKLQKLKRSLSFKTKSLRSK---------SADNFFQRTNSEDMKLQAHMVAEIS----------------------PSSSPLP-----------APGSL---TSTPARAGLHPGG--KAHAFQEYIFKKPTFCDVCNHMIVG----------TNAKHGLRCKACKMSIHHKCTDGLAPQRCMGKLPKGFR---------------------------------RYYSSPLLIHEQFG---------------------------------------CIKEVMPIACGNKVDP-VYETLRFGTSLAQR------------TKKGSSGSGSDSPHRT-----STSDLVEVPEEANGPGG-----------------------------GYDLRKRSNSVFTYPEN-----------------GTDDFRDPAKNINHQGS-------LSKDPLQMNTYVALYKFVPQENEDLEMRPGDIITLLEDSNEDWWKGKIQDRIGFFPANFVQRLQQNEKIFRCVRTFIGCKEQG--QITLKENQICVSSEEEQDGFIRVLSGKK-KGLIPLDVLENI------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1Q7W1-1", "uniprot_id": "A0A8M1Q7W1_DANRE", "id": "A0A8M1Q7W1-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MIPPANMIQEDTMG-----------------------------------------KENERDHRE-PQSPSSISQQESKLQRLKRSLSFKTKSLRSK---------SADNFFQRPIE-DVKFQTELLSDVSSSTGHLSSIGVSVTASPAMSLPPPPPPLPT---------VIPGNLPITICSPSRAPRQTDP--NAHTFLEHIFKKPHFCDICNHMIVACQGGAGKVFGTNAKLGLRCKACKMGIHHKCLDGVGQQRCMGKLPKGFR---------------------------------RYSSSPLLIQEQFG---------------------------------------CIREVMPIACGSKVDP-VYETLRFGTSLAQK------------NKR---TSGSESPQRN-----STSDVAQVPEEKAAHCSR----------------------------AQLIRKPSDNVFMPLEN-----------------GTEHFHVAERKAEESLSER----ELKRDPLLLNTYVALFGFTAQDNQDLEMRPGDRIVLADDSNDDWWKGVIEDRIGFFPAAFAHQVTSSDRVFRCNRTFIGCKEQG--QITLKEGQICVSGENEHNGFIRVASGKK-RGYVPCDVLENI------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KEV7-1", "uniprot_id": "A0A0B4KEV7_DROME", "id": "A0A0B4KEV7-1", "name": "", "aln": "MGISAHAAPASFWNHPRRIRRTPTSDRDGVDQCRPWICRRKDRRPAHPAANRPPESRVCGPSSTFRWDDWAAPAPRTRERATDCARMCMCTSRIPYSVARICARTTSMHSSRPASRSSSFIRRPLTRRQRMAVGGVTRRLWRTMRVYTIHQGRGVRRARAAQAVAAYLRDRRARIGKGWPAQGHGVRISATEQWADKPVVRRPGDPTRRVAAGAVPVLAERLPKVTGSSVKSSSGRRSRRRRIFGWRGPRGGSLSPQGGSMASYNGVLKDYSHSSLNEAFKSQNNVNFKLIKTVSDFSETLSRLYEEHATALQVAVSNYRKKNAELRKERPACHLAIFQAWETFLQEVETDSQACNDVASVLSRQVSRPMLDKSFHRKVQSRKIFTHRESFETIIAKTEEKLSKCRVDYKQCHLAHRQNPSQHSLTEYIDAHNAYVQQLHATNGMLEAYHTDTLPQQMQELEEIHNDLVAIVSDSLMQGAEVIAGKANDQAKRYNSLSNQCAAVSPQQDLVNFVRLLAQPSQAQKIPRRLFASPQAEVGEEAGDHNEMTPCLRNELVFDRHSTLSQRSALESLKREAIELELQIRQLQDSIEALNRTQTRGIEGQLYNKVNELQEDLSMKKFDLRAKQIHLAAIRAQKDLFVSKVEPTSPRNERKFSAATAPSMKTKWLKAFKSLKPAGSGSAQQADSQPPRQNQMYHAVSTVLTLRRNGASSTASEPLRPNLDGSHHLQEYTYKKITACDVCSQILRG-----------HTRQGLRCRICKLNAHGDCAPNLPRCQPKQKLLRRQKSTSELENRVDIEEETGADKSVQAKQMDGSVAGGSALPVPVLSERELGRAPPPDIPIVSVSELALQEQQQQQQQQQQQHQQQQRSLASVAQAAAVRAGRGVRPPPVAMPILGVQLQQQELQQQRGGLPVPSQDISSSSAPHSPRRQKLNLRMKSLSLDSPESSELHGQFRRRTQLPGTGASTSAGSGYYHGGSGGHLEHSTPPSNNSRLHSPSSPSHPGRKLLYATRGMRGGSVDLPDEMEKSQSSASTSPCLSPKTHRLLPTNLYVIIYNFKARHADELDLKAGYKVTVIDNSDPDWWKGKVLGRVGYFPSKYCVRLNANEKPLQVTHNLQVSDSERGENLTLLRDQIVIQTGDEVNGMVMIRAAEHGQGYCPIKYLQEVXQPEEDEPPSDERDRPHKSSMQTSSSRTADKTKRRIRIVVSENHNVAASSVAPAPPTTAFNTTTHHQIPRESDIETKRLNIDYGDEGSADWDKDREVLILSGRRNKNDKNWENWERIREQKLEKMKGICFESYRQSKRDKLLQAKPRPKQLDSTWYTDNIYSNRSDDMDEDYVPDCLKYGPFRTLRDIHELDEKSGVTEERRVEGEGSPGYGLHRSKSCKEFQYPKSQSWCFEGNVFEAGGGVASGSGSSSGAPPPTTSILKNRAGVPKSYSFSATTKTMPFDIIDYELPPVSNTRREKKEALRRNMNALCSSSLDRCCARDQCTSARCLLEDIYPGSRMRPRTTGAGSNRNLSAADWLFEERAGRQRTPAAPTVICCCSAAEDCCCHRQRQQQPPLPARPRSRPLCPGHHPAAEEEEHMHCRYDTDLEHFIRAERERLMLQDKFLDDDERYLAAAPAPRSPGRRYPAGNYHRPPRSKSLLEMQPPTILYDEDTCSDTTEIDLEDFNIDLEKYWEQLDKPPSPINMDMRRNMHSSLKVKNVNVRCYNNGQPIDLHDREHERLMIKKSLLEGMPSPPQLDSSESSTNAGGYPFFDTAPAVAPAPAFHHHPAYGQPQGYGHKVYPTVDTLPSYQYNNFYPEHSHPTVGSVLTQQPTAGIHHPSAGGHSALSLINNIFSIYKPNKYSPENCQMNYESKPEPCKKMNVPSTHRPLGAAAHPYPAHDYMHSSMKRPLLVSADQPHFKIIPEKTGLKISPLLSYEDYGGGGGGEKAHHRLTSTARPLMLPHXWCWTFPWYGNGNGNGNYC", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : :: . : . : . .. .*::.*:..**:*. .**:* . * *. : . : : .: : : . . . . . .: : * : *: :** **:*.::: . ::: **** **:. * .* .: : ** : : . *:* ..::* .: :. .: .* * * :*..* *: .: *...** * .* : **. .:. : .. * .: .. : . . .: * * ** :: * .:. ::*:::.* :.: ::*: ***** : .*:*:**: : :: :: : :.: ...: ::** ..** : :* :*:: : :.:: :* * . * :: ", "identical_positions": 71, "similar_positions": 152, "identity": "3.58%" }, { "cls_id": "homologset.agr.MGI:1201402", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P56484-1", "uniprot_id": "CCR8_MOUSE", "id": "P56484-1", "name": "C-C chemokine receptor type 8", "aln": "---------------------------MDYTMEPNVT--------------MTD-YYPDFFTAPCDAEF---LLRGSMLYLAILYCVLFVLGLLGNSLVILVLVGCKKLRSITDIYLLNLAASDLLFVLSIPFQTHNLLDQWVFGTAMCKVVSGLYYIGFFSSMFFITLMSVDRYLAIVHAVYAIKVRTASVGTALSLTVWLAAVTATIPLMVFYQVASEDGMLQCFQFYE-EQSLRWKLFTH--FEINALGLLLPFAILLFCYVRILQQLRGCLNHNRTRAIKLVLTVVIVSLLFWVPFNVALFLTSLHDLHILDG-CATRQRLALAIHVTEVISFTHCCVNPVIYAFIGEKFKKHLMDVFQKSCSHIFLYLGRQMPVGALERQLSSNQRSSHSSTLDDIL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4ADE0-1", "uniprot_id": "D4ADE0_RAT", "id": "D4ADE0-1", "name": "", "aln": "---------------------------MDYTLEPNVT--------------MTD-YYPDFFTTPCDTEL---LLRGGTLYLAVLYCILFVLGLLGNSLVILVLVACKKLRSITDVYLLNLAASDLLFVLSIPFQTHNLLDQWVFGTVMCKVVSGLYYIGFFSSMLFITLMSVDRYLAVVHPVHAIKVRTARVGTALSLAVWLAAIAATVPLMVFYQVSSEDGMLQCFQLYD-EQSLRWKLFTH--FEVNALGLLLPFAILLFCYVRILQQLRGCLNHNRTRAIKLVLTIVVVSLLFWVPFNVVLFLTSLHDMHILEG-CATRQRLALATHVTEVISFMHCCVNPVIYAFIGEKFKKHLVDVFQKSCSHIFLYVGRQMPVGALERQLSSNQRSSHSSTLDYIL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P51685-1", "uniprot_id": "CCR8_HUMAN", "id": "P51685-1", "name": "C-C chemokine receptor type 8", "aln": "---------------------------MDYTLDLSVTT-------------VTDYYYPDIFSSPCDAEL---IQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYN-QQTLKWKIFTN--FKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDG-CSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PNM1-1", "uniprot_id": "A0A8M9PNM1_DANRE", "id": "A0A8M9PNM1-1", "name": "", "aln": "MSSTIALLSIAAQLLLTDMEDSSIPDLNDHTLYISNVNGPVTDQPTTPVLMITDYSYDDYYNSVDPDSLPCVYPAHGASILPVLYSLFFVLGFLGNTLVIRLVL--KSLRSMTDICLLNLAIADLLLVSSLPFLAHYARDQWIFGGPMCTIVLSVYHIGFYSGIFFIVLMSVDQYLAVVHAVFALKVRTRTYGFLASLVIWVAAVAASFPELIYIDTTDINNQTLCTSYPTTDQSSYHDSKTNGIFKMNIIGLIIPLSVIGFCYSMILIKLLNVR-SSRKQAIRLVVVVMVVFFCCWVPYNIAAFFKALELKRVIPHSCESSKAITLSLQITEAVAYSHSCINPFLYVFVGEKFRKHLFRLLNRTPFSRLQFMKSYVQTTASVYSQTTSLDARSSASV----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M2BKR3-1", "uniprot_id": "A0A8M2BKR3_DANRE", "id": "A0A8M2BKR3-1", "name": "", "aln": "---------------------------MTQAHTTSMEP-------------LTDYYYEVTMCNTEEGSL-------NPHIKAAIFYMVFVLGLVGNIIVLWVLLKSMHVKNMTNLCLLNLAMSDLLMVLSLPFWALYAQGHYLKTDAMCKAMAGAYQVGFYSGIFFVTLMSVDRYLVIVHAVAVLGAKMLRYGIVASVIIWMVSIGAALPEVIFAEVVKDSESNSCQRHYPPESARKWKLFRN--FGENAVGLFISLPIIAYCYLRVLMVVKKTKNSKKNRAIKLILGIVIMFVVFWVPYNVVVFLKTLHEFDMLTS-CEPYKIINMAMDVTETIALTHCCVNPFIYAFVGEKFRKYLASVFSKYLRCLKTYQSTPSQSRISENDTSNTAIFSTSPMKSTQV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . :** * .: . . :: :.**:.::** :*: ::: ::.:*:: ***** :***:* *:** : .::: **. : . * :**:*.::*:.*****:**.:**.* .: .: * .: :*:.:: *:.* ::: :. . . * :.: . : * * :**::.:.:: :** :* : .:.:**:*:: ::: . ***:*:. *:.:*. :: * : : : .:** :: *.*:**.:*.*:****:*:* ::.: : . : *. ", "identical_positions": 75, "similar_positions": 127, "identity": "18.66%" }, { "cls_id": "homologset.agr.MGI:1201403", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35118-1", "uniprot_id": "GFRA3_MOUSE", "id": "O35118-1", "name": "GDNF family receptor alpha-3", "aln": "MGLSWSPRPPL---LMILLLVLSLWLPLGAGNSLATENRFVNSCTQARKKCEANPACKAAYQHLGSCTSSLSRPLPLEESAMSADCLEAAEQLRNSSLIDCRCHRRMKHQATCLDIYWTVHPARSLGDYELDVSPYEDTVTSKPWKMNLSKLNMLKPDSDLCLKFAMLCTLHDKCDRLRKAYGEACSGIRCQRHLCLAQLRSFFEKAAESHAQGLLLCPCAPEDAGCGERRRNTIAPSCALPSVTPNCLDLRSFCRADPLCRSRLMDFQTHCHPMDILGTCATEQSRCLRAYLGLIGTAMTPNFISKVNTTVALSCTCRGSGNLQDECEQLERSFSQNPCLVEAIAAKMRFHRQLFSQDWADSTFSVVQQQ----------------------------------------------------NSNPALRLQP-RLPILSFS------------------ILPLILLQTLW----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6A5Y2-1", "uniprot_id": "A0A8I6A5Y2_RAT", "id": "A0A8I6A5Y2-1", "name": "GDNF family receptor alpha-3", "aln": "MGLSRSPRPPP---LVILLLVLSLWLPLGTGNSLPTENRLVNSCTQARKKCEANPACKAAYQHLDSCTPSLSSPLPSGESATSAACLEAAQQLRNSSLIDCRCHRRMKHQATCLDIYWTVHPVRSLGDYELDVSPYEDTVTSKPWKMNLSKLSMLKPDSDLCLKFAMLCTLNDKCDRLRKAYGEACSGIRCQRHLCLAQLRSFFEKAAESHAQGLLLCPCAPEDAGCGERRRNTIAPSCALPSVAPNCLDLRSFCRADPLCRSRLMDFQTHCHPMDILGTCATEQSRCLRAYLGLIGTAMTPNFISKVNTTVALGCTCRGSGNLQDECEQLEKSFSQNPCLMEAIAAKMRFHRQLFSQDWADSTFSVMQQQQPCSEAPAQATRSVFLHPYLDSAADPLVTGLPQGPLSSPPHPDRLAACDGRENAGLWKKMQPGSLHILSAPDEVLEEARAVTVQNPERPAFKPLLLTPAWAAPP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O60609-1", "uniprot_id": "GFRA3_HUMAN", "id": "O60609-1", "name": "GDNF family receptor alpha-3", "aln": "MVRPLNPRPLPPVVLMLLLLLPPSPLPLAAGDPLPTESRLMNSCLQARRKCQADPTCSAAYHHLDSCTSSISTPLPSEEPSVPADCLEAAQQLRNSSLIGCMCHRRMKNQVACLDIYWTVHRARSLGNYELDVSPYEDTVTSKPWKMNLSKLNMLKPDSDLCLKFAMLCTLNDKCDRLRKAYGEACSGPHCQRHVCLRQLLTFFEKAAEPHAQGLLLCPCAPNDRGCGERRRNTIAPNCALPPVAPNCLELRRLCFSDPLCRSRLVDFQTHCHPMDILGTCATEQSRCLRAYLGLIGTAMTPNFVSNVNTSVALSCTCRGSGNLQEECEMLEGFFSHNPCLTEAIAAKMRFHSQLFSQDWPHPTFAVMAHQ----------------------------------------------------NENPAVRPQPWVPSLFSCT-------------------LPLILLLSLW----", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . .*** *::***: . ***.:*:.*.**.*::*** ***:**:*:*:*.***:**.***.*:* *** *.: .* *****:********.* ******:*.:********* .****:************************.******************:**************** :****:** ** :*******.************:* ************.****.*:****:** :* :********:**************************************:*:***:***.**********:*** ** **:**** ********** *******...**:*: :* * . : ** ::* . : :** . * ", "identical_positions": 288, "similar_positions": 67, "identity": "60.63%" }, { "cls_id": "homologset.agr.MGI:1201406", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62633-1", "uniprot_id": "NTCP2_RAT", "id": "Q62633-1", "name": "Ileal sodium/bile acid cotransporter", "aln": "-------------------------------------------------------------------MDNSS-------VCSPNATFCEGDSCLVTESNFN------------------------------------------------------AILSTVMSTVLTILLAMVMFSMGCNVEINKFLGHIKRPWGIFVGFLCQFGIMPLTGFILSVASG-ILPVQAVVVLIMGCCPGGTGSNILAYWIDGDMDLSVSMTTCSTLLALGMMPLCLFIYTKMWVDSGTIVIPYDSIGISLVALVIPVSIGMFVNHKWPQKAKIILKIGSIAGAILIVLIAVVGGIL-YQSAWIIEPKLWIIGTIFPIAGYSLGFFLARLAGQPWYRCRTVALETGMQNTQLCSTIVQLS-FSPEDLNLVFTFPLIYTVFQLVFAAIILGMYVTYKKCHGKNDAEFLEKTDNDMDPMPSFQETNKGFQPDEK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70172-1", "uniprot_id": "NTCP2_MOUSE", "id": "P70172-1", "name": "Ileal sodium/bile acid cotransporter", "aln": "-------------------------------------------------------------------MDNSS-------VCPPNATVCEGDSCVVPESNFN------------------------------------------------------AILNTVMSTVLTILLAMVMFSMGCNVEVHKFLGHIKRPWGIFVGFLCQFGIMPLTGFILSVASG-ILPVQAVVVLIMGCCPGGTGSNILAYWIDGDMDLSVSMTTCSTLLALGMMPLCLFVYTKMWVDSGTIVIPYDSIGISLVALVIPVSFGMFVNHKWPQKAKIILKIGSITGVILIVLIAVIGGIL-YQSAWIIEPKLWIIGTIFPIAGYSLGFFLARLAGQPWYRCRTVALETGMQNTQLCSTIVQLS-FSPEDLNLVFTFPLIYTVFQLVFAAVILGIYVTYRKCYGKNDAEFLEKTDNEMDSRPSFDETNKGFQPDEK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q12908-1", "uniprot_id": "NTCP2_HUMAN", "id": "Q12908-1", "name": "Ileal sodium/bile acid cotransporter", "aln": "-------------------------------------------------------------------MNDPN-------SCVDNATVCSGASCVVPESNFN------------------------------------------------------NILSVVLSTVLTILLALVMFSMGCNVEIKKFLGHIKRPWGICVGFLCQFGIMPLTGFILSVAFD-ILPLQAVVVLIIGCCPGGTASNILAYWVDGDMDLSVSMTTCSTLLALGMMPLCLLIYTKMWVDSGSIVIPYDNIGTSLVSLVVPVSIGMFVNHKWPQKAKIILKIGSIAGAILIVLIAVVGGIL-YQSAWIIAPKLWIIGTIFPVAGYSLGFLLARIAGLPWYRCRTVAFETGMQNTQLCSTIVQLS-FTPEELNVVFTFPLIYSIFQLAFAAIFLGFYVAYKKCHGKNKAEIPESKENGTEPESSFYKANGGFQPDEK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VXV4-1", "uniprot_id": "Q9VXV4_DROME", "id": "Q9VXV4-1", "name": "P3 protein", "aln": "----MSPHGRPGWEWSYLLLTLAVGFASTHG-----WMAHFRPAALTLQMERGDRVQLKLENVAPSTLQQPTRYHFRLESVDTDLASVPGENATISLDVFNTDTRDWTGDIVVNGHFLGQTKIQVKLYDSQRNTSELPTNWSNDSTLDVKIKRPKRVVDDIFLGTIILLMSLLYISFGAALNLDVLRGLITRPTGPCIGFVMQVVGMPLLSYALGVFIFPQAPAMQLGLFFTGISPSGGASNTWSAVLGGNIHLSVLMTTVSNVAAFATIPLWTITLGQLIFERAGIKVPYGKIASYSSSLVLPLLLGLLVQKRMPQVARVLVRLLKPVSAFIILFIIVFAIINNFYLFYLFSWQIVVAGMALPGLGYIFAFLAAKLLHQNAADALTIAIETGIQNTGIAIFLLTTT-LESPEADITTVVPVSVAVMTPLP---LLGIYL-YNRCWGNKRISEASATASEAERIAGAIH----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VXF5-1", "uniprot_id": "Q9VXF5_DROME", "id": "Q9VXF5-1", "name": "P3 protein", "aln": "MGNVNKNIGRLLVAVGVLMILGLQGVRSEYGDLAGNWLVDYDRDELNFFEDSTWSVDLHIYN----VLPKDSSLDYYFVVYSKDDRRASSPPLEIKKEDFDLLG--------SWRGALYVTGVRFGYSSLEVELKSGAVTETYPKPLPITVLRTQVVDERITTYVSAALALLMFLNLGTVLDMQRLAGIICRPVGPVVGVVSRFVLMPAVGFGLGRALWPDSWPLQLALFYTALSPSGGLANVCAVFLKGNINLSVATTTINSLLALALLPIWILVLGRILYEDDELTVPFGQLSGGAAALVACLAIGVLLRLCLPRTTRFIFRFLKPLSVVLSLCLVGLTVGLNSFVFYEFTWQILVAAVCLPLAGYLSTYLLSKILCRSSTDALTLAIEASVLNMTMPIVLLQSSQLQQPQLDLVLVVPIASSLISLVL----VVLFYGIRRCLGCNRQQDADAFDHKKLLAEQEGDV---------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . : . : . *: : . : . * :: :.:* :::. : * * ** * :*.: :. ** .: *. : :: . .*.* :* : : *::.*** ** ..: *:. :*: : :: : : :*:..:. :** : :*:::. *: ::.:.:: . ...: : : . : : :: : . :* ** :: ::: . *:*:*:.: * : :: : : : ::. ..*: ::: : :: .:* * : . . . ", "identical_positions": 38, "similar_positions": 125, "identity": "7.93%" }, { "cls_id": "homologset.agr.MGI:1201407", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62985-1", "uniprot_id": "SH2B1_RAT", "id": "Q62985-1", "name": "SH2B adapter protein 1", "aln": "MNGAPSPEDGVFPSPPALPPPPPPSWQEFCESHARAAALDLARRFRLYLASHPQYAEPGAEAAFSGRFAELFLQHFEAEVARASGSLSPPVLAPLSPGVEIPPSHDLSLESCRVGGPLAVLGPSRSSEDLAGPLPSSVS-SSTTSSKPKLKKRFSLRSVGRSVRGSVRGILQWRGAVESPSQAGPLETTSGPPVLGGNSNSNSSGGAGTVGRALANDGTSPGERWTHRFERLRLSRGGGTLRDGAGVIQREELLSFMGAEEAAPDPAGVGRGGGAAGLTSGGGGQPQWQKCRLLLRSEGEGGGGSRLEFFVPPKASRPRLSIPCSTITDVRTATALEMPDRENTFVVKVEGPSEYILETTDALHVKAWVSDIQECLSPGPCPAISPRPMTLPLAPGTSFLTKDNTESLELPCLNHSESLPSQDLLLGPSESNDRLSQGAYGGLSD--RPSASFSPSSASIAASHFDSMELLPPELPPRIPIEEGPPAGTVHPLSTPYPPLDTPEAATGSFLFQGEAEGGEGDQPLSGYPWFHGMLSRLKAAQLVLEGGTSSHGVFLVRQSETRRGEYVLTFNFQGKAKHLRLSLNEEGQCRVQHLWFQSIFDMLEHFRVHPIPLESGGSSDVVLVSYVPS-QRQQERSTSRDPTQPSEPPPWTDPPHPGAEEASGAPEVAAATAAAAKERQEKEKAGGGGVQEELVPMAELVPMAELEEAIAPGTE------------------------------------------------AQGGAGSSGDLEVSLMVQLQQLPLGGNGEEGG---HPRAINNQYSFV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91ZM2-1", "uniprot_id": "SH2B1_MOUSE", "id": "Q91ZM2-1", "name": "SH2B adapter protein 1", "aln": "MNGAPSPEDGVFPSPPALPPPPPPSWQEFCESHARAAALDLARRFRLYLASHPQYAEPGAEAAFSGRFAELFLQHFEAEVARASGSLSPPVLAPLSPGVEIPPSHDLSLESCRVGGPLAVLGPSRSSEDLAGPLPSSVP-SSTTSSKPKLKKRFSLRSVGRSVRGSVRGILQWRGAVDSPSQAGPLETTSGPPVLGGNSNSNSSGGAGTVGRALANDGTSPGERWTHRFERLRLSRGGGTLKDGAGMIQREELLSFMGAEEAAPDPAGVGRGGGAAGLTSGGGGQPQWQKCRLLLRSEGEGGGGSRLEFFVPPKASRPRLSIPCSTITDVRTATALEMPDRENTFVVKVEGPSEYILETSDALHVKAWVSDIQECLSPGPCPAISPRPMTLPLAPGTSFFTKDNTDSLELPCLNHSESLPSQDLLLGPSESNDRLSQGAYGGLSD--RPSASFSPSSASIAASHFDSMELLPPELPPRIPIEEGPPAGTVHPLSTPYPPLDTPEAATGSFLFQGESEGGEGDQPLSGYPWFHGMLSRLKAAQLVLEGGTGSHGVFLVRQSETRRGEYVLTFNFQGKAKHLRLSLNEEGQCRVQHLWFQSIFDMLEHFRVHPIPLESGGSSDVVLVSYVPS-QRQQERSTSRDPAQPSEPPPWTDPPHPGAEEASGAPEVAAATAAAAKERQEKEKAGSGGVQEELVPVAELVPMVELEEAIAPGTE------------------------------------------------AQGGAGSSGDLEVSLMVQLQQLPLGGNGEEGG---HPRAINNQYSFV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NRF2-1", "uniprot_id": "SH2B1_HUMAN", "id": "Q9NRF2-1", "name": "SH2B adapter protein 1", "aln": "MNGAPSPEDGASPSSPPLPPPPPPSWREFCESHARAAALDFARRFRLYLASHPQYAGPGAEAAFSRRFAELFLQHFEAEVARASGSLSPPILAPLSPGAEISP-HDLSLESCRVGGPLAVLGPSRSSEDLAGPLPSSVSSSSTTSSKPKLKKRFSLRSVGRSVRGSVRGILQWRGTVDPPSSAGPLETSSGPPVLGGNSNSNSSGGAGTVGRGLVSDGTSPGERWTHRFERLRLSRGGGALKDGAGMVQREELLSFMGAEEAAPDPAGVGRGGGVAGPPSGGGGQPQWQKCRLLLRSEGEGGGGSRLEFFVPPKASRPRLSIPCSSITDVRTTTALEMPDRENTFVVKVEGPSEYIMETVDAQHVKAWVSDIQECLSPGPCPATSPRPMTLPLAPGTSFLTRENTDSLELSCLNHSESLPSQDLLLGPSESNDRLSQGAYGGLSD--RPSASISPSSASIAASHFDSMELLPPELPPRIPIEEGPPTGTVHPLSAPYPPLDTPETATGSFLFQGEPEGGEGDQPLSGYPWFHGMLSRLKAAQLVLTGGTGSHGVFLVRQSETRRGEYVLTFNFQGKAKHLRLSLNEEGQCRVQHLWFQSIFDMLEHFRVHPIPLESGGSSDVVLVSYVPSSQRQQEPTTSHDPPQPPEPPSWTDPPQPGAEEASRAPEVAAAAAAAAKERQEKEKAGGGGVPEELVPVVELVPVVELEEAIAPGSE------------------------------------------------AQG-AGSGGDAGVPPMVQLQQSPLGGDGEEGG---HPRAINNQYSFV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4LHY5-1", "uniprot_id": "A0A0B4LHY5_DROME", "id": "A0A0B4LHY5-1", "name": "", "aln": "MGGNSTGANTSAFSAGGYIGPTSASSHHSLGTSSAAAAAAAGSDLIPAPIGTGNAMGVSSYAYGGTSWEEFCERHARVAASDFAKACITYINGNLPP----------------------------------------------EEARNIQHRSFAQKFVESFSAHYDTEFFKRRSTLKSGAGSLDFEEEHEVPKLLSKSLLRR-----LSFKGLRKGKISLLQAFFHKNS-DDLDGSGGSGKQSKTKLAKIVVECRKEGTVNNLTPESLDQPTGSQ----------KWEKCRLVLVK---AVGGYMLEFYTPHKATKPRSGVFCFLISEARETTALEMPDRLNTFVLKADNNMEYVIEAESAEEMRSWLATIRYCMRTPPTQQPTIE-----------------SDGVMASAMQTSPTLPSPNPIGGIQNPQYQQQRGSNGNLVGGGAPLTSSLSADSALGQGGATSASELNVINELGTSPTSGPPDIPVRPHRGEQR-LSASSNFDGIEGTENDADVADLTAEMSVFPWFHGTLTRSEAARMVLHSDAAGHGYFLVRQSETRRGEFVLTFNFQGRAKHLRLTISEKGQCRVQHLWFPSIQEMLEHFRHNPIPLESGGTSDVTLTEWVHSHSRLNDPTTAANHDSGQLNDLSTNGNGNGNGNGYDNGQGSSTASNAAGGTASGAAGGGHPSPRHCNEVITMNLSVRLKTNEIELPQEPTHVYFPEQVYFHLDPTTLTVHGSPPPAQNFLDQPHLRASNASLQAAAHHQAGSSGNRHPSDGGSNSGGAGGGSGSSGGAECTGRAVDNQYSFT", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.* .: : *. *...* :. : : *** . : . : .: * . : *: :* .. .: : : . : . *.* .:: :: *: : * ::: *.::.. : : :* * * .:* . :.* .. * : : *: . *. .**: ::. : : : . . * .:.: * :*:****:* . . ** ***:.* **::** .: * *::.* :******** ****:*.:. **::*: .* .:::*:: *: *: . * : . ::.: ..:: * :*** : : * .:.: : .:*: *.* . * :* .:.:::. . * . * . .*** .*:* *.:.. * :.:.: .: :* :***** *:* :**::** ..:..** ************:********:******::.*:********** ** :****** :********:***.*..:* * .* :: :*: : . *: * :. : ::::: ** . .*. .. : : ..*: .: *: ***.*: . . . . **.*..** **::*****.", "identical_positions": 185, "similar_positions": 221, "identity": "22.81%" }, { "cls_id": "homologset.agr.MGI:1201408", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O54781-1", "uniprot_id": "SRPK2_MOUSE", "id": "O54781-1", "name": "SRSF protein kinase 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------MSVNSEK---------SSSSERPEPQQKAPLVPPPPPPPPPPP--LPDPAPP--EPEEEILGSDDEEQEDPADYCKGGYHPVKIGDLFN-GRYHVIRKLGWGHFSTVWLCWDMQGKRFVAMKVVKSAQHYTETALDEIKLLKCVRESDPSDPN---KDMVVQLIDDFKISGMNGIHVCMVFEVLGHHLLKWIIKSNYQGLPVRCVKSIIRQVLQGLDYLHSKCKIIHTDIKPENILMCVDDAYVRRMAAEATEWQKAGAPPPSGSAVSTAPQQKP----IGKISKNKKKKLKKKQKRQAELLEKRLQEIEELEREAER-------------KILEENITSAEASGEQDGEYQPEVTLK--------AADLEDTTEEETAKDN--------------------------------------------------------------GEVEDQEEKEDAEKENAEKDEDDVEQELANLDPTWVESPKANGHIENGPFSLEQQLEDEEDDEDDCANPEEYNLDEPNAESDYTYSSS---------------YEQFNGELPNGQHKTSE-----FPTPLFSGPLEPVACGSVISEGSP--------------LTEQEESSPSH-DRSRTVSASSTGDLPKTKTRAADLLVNPLDPRNADK-IRVKIADLGNACWVHKHFTEDIQTRQYRSIEVLIGAGYSTPADIWSTACMAFELATGDYLFEPHSGEDYSRDEDHIAHIIELLGSIPRHFALSGKYSREFFNRRGELRHITKLKPWSLFDVLVEKYGWPHEDAAQFTDFLIPMLEMVPEKRASAGECLRHPWLNS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6GM61-1", "uniprot_id": "A0A8I6GM61_RAT", "id": "A0A8I6GM61-1", "name": "SRSF protein kinase 2", "aln": "MERRAARPAGVRSGGGGWEEEGSAAGPSARELVACGGRRSKEAEAGCGRPWAREAVGARRSSRTGGSRGGRPGRGPGPGPQCSGDAEGGARRGRGRGAGPRGRVPLAPAGAAAAAQARFPPPRPASEWRLHPGAADCRVAAASAAEPPARLPRVGMSSRKVLAIQARKRRPK----REKHPKKPEPQQKAPLVPPPPPPPPPPP--LPDPVPP--EPEEEILGSDDEEQEDPADYCKGGYHPVKIGDLFN-GRYHVIRKLGWGHFSTVWLCWDMQGKRFVAMKVVKSAQHYTETALDEIKLLKCVRESDPSDPN---KDMVVQLIDDFKISGMNGIHVCMVFEVLGHHLLKWIIKSNYQGLPVRCVKSIIRQVLQGLDYLHSKCKIIHTDIKPENILMCVDGAYVRRMAAEATEWQKAGAPPPSGSAVSTAPQQKP----IGKISKNKKKKLKKKQKRQAELLEKRLQEIEELEREAER-------------KILEENTTSAEASSEQDGECQPEVKLK--------EAELEDTTEEETAKDN--------------------------------------------------------------GEVEDQEEKEDTEKENTEKDEDDVEQELENIDPTWMESPKANGHIENGLFLLEQQLEDEEDEEDDCANPEEYNLDEPNAESDYTYSSS---------------YEQFNGELPNGQPKSPE-----FPTPLFSGPLEPVASDSVLSEGSP--------------LTEPEESSPSR-DRSRTVSASSTGDLPKTKTRAADLLVNPLDPQNADK-IRVKIADLGNACWVHKHFTEDIQTRQYRSIEVLIGAGYSTPADIWSTACMAFELATGDYLFEPHSGEDYSRDEDHIAHIIELLGSIPRHFALSGKYSREFFNRRGELRHITKLKPWSLFDVLVEKYGWPHEDAAQFTDFLIPMLEMVPEKRASAGECLRHPWLNS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P78362-1", "uniprot_id": "SRPK2_HUMAN", "id": "P78362-1", "name": "SRSF protein kinase 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------MSVNSEK---------SSSSERPEPQQKAPLVPPPPPPPPPPPPPLPDPTPP--EPEEEILGSDDEEQEDPADYCKGGYHPVKIGDLFN-GRYHVIRKLGWGHFSTVWLCWDMQGKRFVAMKVVKSAQHYTETALDEIKLLKCVRESDPSDPN---KDMVVQLIDDFKISGMNGIHVCMVFEVLGHHLLKWIIKSNYQGLPVRCVKSIIRQVLQGLDYLHSKCKIIHTDIKPENILMCVDDAYVRRMAAEATEWQKAGAPPPSGSAVSTAPQQKP----IGKISKNKKKKLKKKQKRQAELLEKRLQEIEELEREAER-------------KIIEENITSAAPSNDQDGEYCPEVKLK--------TTGLEEAAEAETAKDN--------------------------------------------------------------GEAEDQEEKEDAEKENIEKDEDDVDQELANIDPTWIESPKTNGHIENGPFSLEQQLDDEDDDEEDCPNPEEYNLDEPNAESDYTYSSS---------------YEQFNGELPNGRHKIPESQFPEFSTSLFSGSLEPVACGSVLSEGSP--------------LTEQEESSPSH-DRSRTVSASSTGDLPKAKTRAADLLVNPLDPRNADK-IRVKIADLGNACWVHKHFTEDIQTRQYRSIEVLIGAGYSTPADIWSTACMAFELATGDYLFEPHSGEDYSRDEDHIAHIIELLGSIPRHFALSGKYSREFFNRRGELRHITKLKPWSLFDVLVEKYGWPHEDAAQFTDFLIPMLEMVPEKRASAGECLRHPWLNS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PYJ9-1", "uniprot_id": "A0A8M9PYJ9_DANRE", "id": "A0A8M9PYJ9-1", "name": "non-specific serine/threonine protein kinase", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------MSSRKVLAIQARKRRPRGKKEKTVPHRRPDTQKAPSDPPPPPPPPPPPPPPPPEPVAPL-EPEEEILGSDDEEQEDPADYCKGGYHPVKIGDLFN-SHYHVIRKLGWGHFSTVWLCWDIQGKRFVAMKVVKSAQHYTETALDEIKLLRCVRETDPEDPN---KDMVVQLIDDFKISGVNGIHVCMVFEVLGHHLLKWIIKSNYQGLPLPCVKSIIRQVLQGLDYLHSKCKIIHTDIKPENILMCVDDAFVRRMAVEATEWQKAGAPPPSGSAVSTAPQLKQ----VGKISKNKKKKMKKKQKRQAELLERRMLEIEALEREAEKQRADGETNAEHGPTLADSEEDEEEEEDEEEEEKQRPVRLTNHTCAEPEQPEVEDSDDGEESRTHTHTPTHTPTHTATHTPTHTPTETPTQTPTHTPTHAHTPTHTPLGRTDTPQEPERSGGAEELDGSRDGRQEEEEKAEEVEKAEEVEEETAAAPSESTEEETRQCVKEDEQTKHTRDTQDEEEEEEEEDDEEDEEDEEEEEEEEEQSTAAKTNGHVCVCVQECVSPAAPTLLCPLVESEISTTDRDASDASYELFNGDTSSLSNGARHRGTTPRFPELPLDPDPTHTLQDQAQGPDRHSDRSRTVSSSSTGDNPKARIRAADLLVNPLDPRNAEA-LRVKIADLGNACWVHKHFTEDIQTRQYRSIEVLIGAGYSTPADIWSTACMAFELATGDYLFEPHSGEDYSRDEDHIAHIIELLGCIPRHFALSGKYSREFFNRRGELRHITKLKPWSLFDVLVEKYGWAAEEAGHFTHFLLPMLEMVPEKRASASECLHHPWLSS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A6M3Q7C8-1", "uniprot_id": "A0A6M3Q7C8_DROME", "id": "A0A6M3Q7C8-1", "name": "non-specific serine/threonine protein kinase", "aln": "-------------------------------------------------------------------MNKADVNRRVLAIQAKKKRHKNRKRGKQNGTNPQEQSNSSQNQNPKPSSNPIPEPNRSSENLQAPDNANN----------------SHLNAPSSAAFSKATATATASTSSGGSAGTPDQYQPPKKTQAKAKPNTQKEHQQQPPRSSSNESYESETFSDNEDQELMEDYCKGGYHPVNIGDLFH-DRYHVIRKLGWGHFSTVWLCWDLQAMGYVAIKIVKSAPHFAETARDEIKILKTVRETDPSNPR---RHKTVQMLDDFKITGVNGTHICMVFEVLGDNLLKLIRKSNYRGIPLANVKTITRQVLEGLDYLHTCCKIIHTDIKPENVLLCVDEPHVRSLATEATQLYCMNSKMYP-SLVSRAPKEYREPPITGKMSKNRKKKLKKKAKKRMELFKQQRDYLEQAD--------------------GQGAINPNEVQNGDAGISDADEYFD--------ANSVEDNVHVAAGQPS----------------------------------------------------------------RKQREERKAPPEQSEEAQEQDPLTEGTD-KAKKKKKKKNKNKSNQSKGQQPPQLENSTSSAESSSALKSQQANGSNSTTNNKSNTN---------------SSGTLKGQSNGKKMPLR------PKQEKQGSNHQLNNNNSKPNSNS---------------DSKISSGSVENTSSATNGPHSNSTLPTPPPPPQAKHKAKKDPALDECNVHVKIADLGNACWVDRHFTEDIQTRQYRSLEVIIGAGYNTSADIWSTACMVFELATGDYLFEPHSGESYTRDEDHLAHIIELLGPIPREILLNGTYAAKSFTRSCELRNISGLKPWGLMDVLLEKYEWSQKDAASFASFLTPMLEFDPNKRATAAECLQHPWLRXDTMQPGCWLRATQPATADGDGGALAGTGTGKGTRARATALKGGSPAVPADGEVGRGYIESSASVATLASISSIASTSAAAMAALKARPYLVAPFVTTASAPPTPHPHASISTSTARTAPATPTRRRIAPEDDLNLVEDLDVALAQIEDTQTHTKNKSQRFFWRKALRRVFQRRKXRRRRQDLPRWHRPARRCRRRNLAERVRRICACCAYGQILLRAARVALLSCIRWRTRGNIRNNNFYFSNH", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q03656-1", "uniprot_id": "SKY1_YEAST", "id": "Q03656-1", "name": "Serine/threonine-protein kinase SKY1", "aln": "-----------------------------------------------------------------------------MGSSINYPGFVTKSAHLADTSTDASISCEEATSSQEAKKNFFQRDYNMMKKAPAP-------------------TKSKLSLALQTSKSSSSANGTVQEDTSSKTEDFSTKSIKKKPDSGVESHVSIQSDSGPQSDSDLDSDSSISSCDERNEESLKDYRPGGYHPAFKGEPYKDARYILVRKLGWGHFSTVWLAKDMVNNTHVAMKIVRGDKVYTEAAEDEIKLLQRVNDADNTKEDSMGANHILKLLDHFNHKGPNGVHVVMVFEVLGENLLALIKKYEHRGIPLIYVKQISKQLLLGLDYMHRRCGIIHTDIKPENVLMEIGDVEGIVQMVEALDKQKR-------EAKRLQRHVSR-----------------------------------------------------------SSDITANDSSDEKWAECQTSMPCG----------------SSSNSKSR--------------------------------------------------------------SIEKDLSKRCFRRPRRHTIITGSQPLPSPISSSNFFEMRAHFCGSSHNSFSSVSGNRNIPSSINNNSINNGIGIKNSNNSFLNSVPHS--------------VTRMFINEDSNDNNNNDN------SKNKNNNNNNSNNNNNEDIMNTP--------------LHEEQLADSLSTFDISNISQSSDTNGPYISNTMDSNSNVSTDINSPENLIQIKIADLGNACWYDEHYTNSIQTREYRSPEVLLGAPWGCGADIWSTACLIFELITGDFLFEPDEGHSYTKDDDHIAQIIELLGELPSYLLRNGKYTRTFFNSRGLLRNISKLKFWPLEDVLTEKYKFSKDEAKEISDFLSPMLQLDPRKRADAGGLVNHPWLKDTLGMEEIRVPDRELYGSGSDIPGWFEEVRDHKRH------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . . . . . . :. .. .*:.::* ** *****. *: :: :* ::*************. *: .**:*:*:. ::*:* ****:*: *.::* . . ::::*.*: .* ** *: *******.:** * * :::*:*: ** * :*:* ****:* * **********:*: :. .** : . : . .. . .: . .:. . . ... : .: : .. :. : . : . . :.. . .. . .. . . . . * * * : :::********** ..*:*:.****:*** **::** :. ********: *** ***:****..*..*::*:**:*:****** :* : .*.*: *. **:*: ** * * *** *** :. .:* :: ** ***:: *.*** *. :.**** ", "identical_positions": 169, "similar_positions": 153, "identity": "13.78%" }, { "cls_id": "homologset.agr.MGI:1201409", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O70477-1", "uniprot_id": "PKNX1_MOUSE", "id": "O70477-1", "name": "Homeobox protein PKNOX1", "aln": "MMATQTLSIDSYQDG-QQMQVVTELKTEQDPNCSDPDAEG-VSPPPIESQTPMDADKQAIYRHPLFPLLALLFEKCEQSTQGSEGTTSASFDVDIENFVRKQEKDGKPFFCEDPETDNLMVKAIQVLRIHLLELEKVNELCKDFCSRYIACLKTKMNSETLLSGEPGSPYSPVQSQQIQSAITGTLSPQGIVVPASALQQGNVTMATV------AGGTVYQPVTVVTPQGQVVTQALSPGTIRIQNSQLQLQLNQDLSILHQEDGSSKNKRGVLPKHATNVMRSWLFQHIGHPYPTEDEKKQIAAQTNLTLLQVNNWFINARRRILQPMLDSSCSETPKTKKKPAQNRPVQRFWPDSLASGVAQATPSELAMSEGAVVTITTPVNMNVDSLQSLSSDGATLAVQQVMMAGQSEDESVDSTEDEGGALAPTHISGLVLENSDSLQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5BJP1-1", "uniprot_id": "Q5BJP1_RAT", "id": "Q5BJP1-1", "name": "", "aln": "MMATQTLSIDSYQDG-QQMQVVTELKTEQDPNCSDPDAEG-VSPPPIESQTPMDADKQAIYRHPLFPLLALLFEKCEQSTQGSEGTTSASFDVDIENFVRKQEKDGKPFFCEDPETDNLMVKAIQVLRIHLLELEKVNELCKDFCSRYIACLKTKMNSETLLSGEPGSPYSPVQSQQIQSAITGTLSPQGIVVPASALQQGNVTMATV------AGGTVYQPVTVVTPQGQVVTQALSPGTIRIQNSQLQLQLNQDLSILHQEDGSSKNKRGVLPKHATNVMRSWLFQHIGHPYPTEDEKKQIAAQTNLTLLQVNNWFINARRRILQPMLDSSCSETPKTKKKPAQNRPVQRFWPDSLASGVAQATPGELAMSEGAVVTITTPVNMNVDSLQSLSSDGATLAVQQVMMAGQSEDESVDSTEDEGGALAPTHISGLVLENSDSLQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P55347-1", "uniprot_id": "PKNX1_HUMAN", "id": "P55347-1", "name": "Homeobox protein PKNOX1", "aln": "MMATQTLSIDSYQDG-QQMQVVTELKTEQDPNCSEPDAEG-VSPPPVESQTPMDVDKQAIYRHPLFPLLALLFEKCEQSTQGSEGTTSASFDVDIENFVRKQEKEGKPFFCEDPETDNLMVKAIQVLRIHLLELEKVNELCKDFCSRYIACLKTKMNSETLLSGEPGSPYSPVQSQQIQSAITGTISPQGIVVPASALQQGNVAMATV------AGGTVYQPVTVVTPQGQVVTQTLSPGTIRIQNSQLQLQLNQDLSILHQDDGSSKNKRGVLPKHATNVMRSWLFQHIGHPYPTEDEKKQIAAQTNLTLLQVNNWFINARRRILQPMLDSSCSETPKTKKKTAQNRPVQRFWPDSIASGVAQPPPSELTMSEGAVVTITTPVNMNVDSLQSLSSDGATLAVQQVMMAGQSEDESVDSTEEDAGALAPAHISGLVLENSDSLQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B5L4-1", "uniprot_id": "A0A8M3B5L4_DANRE", "id": "A0A8M3B5L4-1", "name": "", "aln": "MMAAQSVSIDKYPEGDQQMQVMEQSENDLKKGFSNGNTGNSSSPVSNEPQTQMDIDKACIYRHPLFPLLALLFEKCEQSTLGSDCVTSASFDVDIENFVRSQEKDGKAFFSEDPDLDNLMVKAIQVLRIHLLELEKVSDLCKDFCSRYISCLKAKMNSETLLSGDPGSPYSPVHD-QLSNPFSGPLSPQSLLIPSSGLQQGSVTVTTVNPSQVATGNTVYQPVTVVTPQGQVVTQAISPGALHIQNSQLQLQLNQDLSFFGGDDSSPKNKRGVLPKQATNVMRSWLFQHIAHPYPTEEEKKQIATQTNLTLLQVNNWFINARRRILQPMLDANSTEASKSKKKVAQSRPLHRFWSDSIASTGSQQ---QLTMPDGSLVTVG----MNVDGFQALSSDGATLAMQQVLMGNHSEDETDESGNEDDTDMSTANMPGLGLDVSD---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P53147-1", "uniprot_id": "TOS8_YEAST", "id": "P53147-1", "name": "Homeobox protein TOS8", "aln": "-MGTSIVNLNQKIEL-PPIQVLFESLNR-------------------ENETKPHFEERRLYQP--------------------NPSFVPRTNIAVGSPVNPVPVSSPVFFIG-PSPQRSIQNHNAIMTQNIRQYPVIYNNNREVISTGERNYIITVGGPPVTSSQPEYEHISTPNFYQEQRLAQPHPVNESMMIG--------------------GYTNPQPISISR--GKMLSGNISTNSVRGSNNGYSAKE---------KKHKAHGKRSNLPKATVSILNKWLHEHVNNPYPTVQEKRELLAKTGLTKLQISNWFINARRRKIFSGQN----DANNFRRKFSSSTNLAKF-------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.:. :.::. : :**: : . * :* . :: :*: : . :: : . *. .. ** *. :. : : :: :: : : : ::. * .:.. .: *.:* : .. . .. :: . . : :: . * * **::: *:::: :*..::: .*. . : .. ..:.**. *** :..::..**.:*: :**** :**::: ::*.** **:.********* : . : :: : ::* :.. : :* ", "identical_positions": 50, "similar_positions": 122, "identity": "11.26%" }, { "cls_id": "homologset.agr.MGI:1201412", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ACD6B7R1-1", "uniprot_id": "A0ACD6B7R1_DANRE", "id": "A0ACD6B7R1-1", "name": "", "aln": "MVFCCADLLCSCWCSLAVIALIAAVWFFRDSRQISGIHEKHVLITGCDSGFGNLVARQLDRQGFLVIAACLTETGASKLRATAS-PRLKTLQLNVTDSTSIDRALEYVRRETGGKGLWGLVNNAGVSVPIGPMDWMQLHDFKKVLDVNLTGVIAVTLKFLPLLKKAQGRVVNVASILGRLSII-GGGYCLSKFGVEAFSDSLRRDMVHFGVKVSIIEPGFFKTQVTDLGLIEDDLKKRWSNLPEQVRRDYGDSYLQEYLKVLEFSHKMLASSDLSKVTSCMRHALSARHPRTRYAAGWDAKFLWIPLSYLPTCVVDIITKALVPS-SKPL-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1RCW4-1", "uniprot_id": "F1RCW4_DANRE", "id": "F1RCW4-1", "name": "", "aln": "MYEFLSNSCPSTYALGTFAILWVLVWFYRDNLKITRVSEKHVFVTGCDSGFGNLLCKRLDKRGFRVLAGCLTEKGADDLKRAAG-PFLKTCILDVTSSASIQKAMEWTKKEVGDKGLWGLVNNAGRSLPMGPSEWMKIEDFESTLKVNMTGVIETTMTFLPLVKKARGRVVNVASVLGRVAAN-GGGYCISKFAVESFSDCLRRDIQGFGVNVCIIEPGFFKTQVTSLEPIERELHRLWNQLTPEVKESYGDKYLDKYIWIQRLIMNAICDSDLSKVTNCMEHALLAVHPRTRYSAGWDAKFLWIPLSYMPACFVDIALKLVMPKPAKGV-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O55240-1", "uniprot_id": "RDH5_MOUSE", "id": "O55240-1", "name": "Retinol dehydrogenase 5", "aln": "--MWLPLLLG--------ALLWAVLWLLRDRQSLP-ASDAFIFITGCDSGFGRLLALQLDQKGFQVLAGCLTPSGAEDLQQMAS-SRLHTTLLDITDPQNVQQVAKWVKTRVGETGLFGLVNNAGVAGIIGPTPWLTQDDFQRVLSVNTLGPIGVTLALLPLLQQARGRVVNITSVLGRIAAN-GGGYCVSKFGLEAFSDSLRRDMAPFGVQVSIVEPGFFRTPVTNLESLESTLKACWARLPPAIQAHYGEAFLDTYLRVQRRIMNLICDPELTKVTSCLEHALTARHPRTRYSPGWDAKLLWLPASYLPARVVDAVLTWILPRPAQSVS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92781-1", "uniprot_id": "RDH5_HUMAN", "id": "Q92781-1", "name": "Retinol dehydrogenase 5", "aln": "--MWLPLLLG--------ALLWAVLWLLRDRQSLP-ASNAFVFITGCDSGFGRLLALQLDQRGFRVLASCLTPSGAEDLQRVAS-SRLHTTLLDITDPQSVQQAAKWVEMHVKEAGLFGLVNNAGVAGIIGPTPWLTRDDFQRVLNVNTMGPIGVTLALLPLLQQARGRVINITSVLGRLAAN-GGGYCVSKFGLEAFSDSLRRDVAHFGIRVSIVEPGFFRTPVTNLESLEKTLQACWARLPPATQAHYGGAFLTKYLKMQQRIMNLICDPDLTKVSRCLEHALTARHPRTRYSPGWDAKLLWLPASYLPASLVDAVLTWVLPKPAQAVY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P40471-1", "uniprot_id": "AYR1_YEAST", "id": "P40471-1", "name": "NADPH-dependent 1-acyldihydroxyacetone phosphate reductase", "aln": "------------------------------MSELQSQPKKIAVVTGASGGIGYEVTKELARNGYLVYACARRLEPMAQLAIQFGNDSIKPYKLDISKPEEIVTFSGFLRANLPDGKLDLLYNNAGQSCTF-PALDATDAAVEQCFKVNVFGHINMCRELSEFLIKAKGTIVFTGSLAGVVSFPFGSIYSASKAAIHQYARGLHLEMKPFNVRVINAITGGVATDIADKRPLPETSIYNFPEGREAFNSRKTMAKDNKPMPADAYAKQLVKD--ILSTSDPVDVYRGTFANIMRFVMIFVP-YWLLEKGLSKKFKLDKVNNALKSKQKNKDD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: . .:**...*:* : .* :.*: * * . .* . ::. *:::.. .: : . . * * **** : : * .: :.** * * : :: :*:* :: *: * :: *. *. ** .:. :: *: :: *.:.* .* . * ::. : : . . : : : . : ..: : : *: : . : . :* . : . : ", "identical_positions": 36, "similar_positions": 88, "identity": "10.88%" }, { "cls_id": "homologset.agr.MGI:1201414", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O55233-1", "uniprot_id": "CER1_MOUSE", "id": "O55233-1", "name": "Cerberus", "aln": "MHLLLVQLLVLLPLGKADLCVDGCQSQGSLSFPLLERGRRDLHVANHEEAEDKPDLFVAVPHLMGTSLAGEGQRQRGKMLSRLGRFWKKPETEFYPPRDVESDHVSSGMQAVTQPADGRKVERSP-LQEEAKRFWHRFMFRKGPAFQGVILPIKSHEVHWETCRTVPFNQTIAHEDCQKVVVQNNLCFGKCSSIRFP---GEGADAHSFCSHCSPTKFTTVHLMLNCTSPTPVVKMVMQVEECQCMVKTERGEERLLLAGSQGSFIPGLPASKTNP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95813-1", "uniprot_id": "CER1_HUMAN", "id": "O95813-1", "name": "Cerberus", "aln": "MHLLLFQLLVLLPLGKTTRHQDGRQNQSSLSPVLLPRNQRELPTGNHEEAEEKPDLFVAVPHLVATSPAGEGQRQREKMLSRFGRFWKKPEREMHPSRDSDSEPFPPGTQSLIQPIDGMKMEKSP-LREEAKKFWHHFMFRKTPASQGVILPIKSHEVHWETCRTVPFSQTITHEGCEKVVVQNNLCFGKCGSVHFP---GAAQHSHTSCSHCLPAKFTTMHLPLNCTELSSVIKVVMLVEECQCKVKTEHEDGHILHAGSQDSFIPGVSA-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N1Z238-1", "uniprot_id": "A0A8N1Z238_DANRE", "id": "A0A8N1Z238-1", "name": "", "aln": "---MTFQVGFFVLLSVTTIGAFPRNAFQREFHRHVAKDFESSGNGPDEPVRGSVRIVKLNPHFLRRAAVSHVP------------FRNSPSRGAFPAFLALGR---PGPAILTHSKPAPQVSSSADRRKQGLEMWKKVVHKSERKKEAVALRINPKDMNKQSCAAVPFTQRITEEGCETVTVHNNLCYGQCSSMFVPSSGGSHGQQKAQCTRCGPSRARSVLLHLRCGS-EVRERRVLIVEECKCETSSEE-------AKVQNTDMFNL-------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .*: .:: *. : : : :. .. . .* .. . :. **:: : ... * :.*. .*. . .* : :. . ::. *. :::. .:*::.:.:. :.* * *:.:::: ::* :***.* *:.*.*:.*.*:****:*:*.*: .* * . :: *::* *:: :: * *.* . : *: ****:* ..:*. * *.: : .: ", "identical_positions": 48, "similar_positions": 102, "identity": "17.39%" }, { "cls_id": "homologset.agr.MGI:1201606", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ESG5-1", "uniprot_id": "HS3S1_RAT", "id": "Q9ESG5-1", "name": "Heparan sulfate glucosamine 3-O-sulfotransferase 1", "aln": "MTLLLLGAVLLVAQPQLVPSHPAAPGPGLKQQGLLRKVIILPEDTGEGAATNGSTQQLPQTIIIGVRKGGTRALLEMLSLHPDVAAAENEVHFFDWEEHYSQGLGWYLTQMPFSSPHQLTVEKTPAYFTSPKVPERIHSMNPTIRLLLILRDPSERVLSDYTQVLYNHLQKHKPYPPIEDLLMRDGRLNVDYKALNRSLYHAHMLNWLRFFPLGHIHIVDGDRFIRDPFPEIQKVERFLKLSPQINASNFYFNKTKGFYCLRDSGKD-RCLHESKGRAHPQVDPKLLDKLHEYFREPNKKFFKLVGRTFDWH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35310-1", "uniprot_id": "HS3S1_MOUSE", "id": "O35310-1", "name": "Heparan sulfate glucosamine 3-O-sulfotransferase 1", "aln": "MTLLLLGAVLLVAQPQLVHSHPAAPGPGLKQQELLRKVIILPEDTGEGTASNGSTQQLPQTIIIGVRKGGTRALLEMLSLHPDVAAAENEVHFFDWEEHYSQGLGWYLTQMPFSSPHQLTVEKTPAYFTSPKVPERIHSMNPTIRLLLILRDPSERVLSDYTQVLYNHLQKHKPYPPIEDLLMRDGRLNLDYKALNRSLYHAHMLNWLRFFPLGHIHIVDGDRLIRDPFPEIQKVERFLKLSPQINASNFYFNKTKGFYCLRDSGKD-RCLHESKGRAHPQVDPKLLDKLHEYFHEPNKKFFKLVGRTFDWH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14792-1", "uniprot_id": "HS3S1_HUMAN", "id": "O14792-1", "name": "Heparan sulfate glucosamine 3-O-sulfotransferase 1", "aln": "MAALLLGAVLLVAQPQLVPSRPAELG----QQELLRKAGTLQDDVRDGVAPNGSAQQLPQTIIIGVRKGGTRALLEMLSLHPDVAAAENEVHFFDWEEHYSHGLGWYLSQMPFSWPHQLTVEKTPAYFTSPKVPERVYSMNPSIRLLLILRDPSERVLSDYTQVFYNHMQKHKPYPSIEEFLVRDGRLNVDYKALNRSLYHVHMQNWLRFFPLRHIHIVDGDRLIRDPFPEIQKVERFLKLSPQINASNFYFNKTKGFYCLRDSGRD-RCLHESKGRAHPQVDPKLLNKLHEYFHEPNKKFFELVGRTFDWH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BKC1-1", "uniprot_id": "A0A8M2BKC1_DANRE", "id": "A0A8M2BKC1-1", "name": "Sulfotransferase", "aln": "-MALVLALLLCFST----------------QSSVLVSGVISPPDA--ALTPRANARHLPDIIIIGVRKAGTRALIQMLRLHTSIAAAQNEVHFFDWDSHYERGLDWYVDQMPEAQPGQLTVEKTPAYFTSRDVPQRIRLAKPDARLLLIVREPTERLLSDYTQVYHNRLEKRKRPQPLETLLLRNGELNLDYKPLNRSLYHTHMQRWLQAFPISSFHLVDGDALVREPLAEMQKVEAFLKLEPQISQNNFYFNQTRGFFCLRDGRQQQRCLHSSKGRKHPQVSPHILSKLQHFFHEPNRRFFELVGRTFDWK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:*. :* .: *. :* . *. . :....:::**: *******.*****::** **..:***:********:.**.:**.**: *** : * ************* .**:*: :* *****:*:*:**:******* :*:::*:* .:* :*:*:*.**:***.*******.** .**: **: :*:**** ::*:*:.*:**** ****.***. .*****:*:**:****. :: ****.**** ****.*::*.**:.:*:***::**:********:", "identical_positions": 164, "similar_positions": 88, "identity": "52.56%" }, { "cls_id": "homologset.agr.MGI:1201607", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AYB8-1", "uniprot_id": "GO45_RAT", "id": "Q6AYB8-1", "name": "Golgin-45", "aln": "MEKMTTLKSFESKGILTSTPIRGAGDGMETEEPPKSVEVTHGVQPINQHVLPSPRKK-------------------VPSDSPGVLQLG---KILNEKTVEVEAVRIFVPKAAITHDIPT-KSAKVKSLGHHREELHNQSEVVTDP-----------------------------------------------RKELSEVKKVLEKLKNSERRLLQDKEGLSNQLRVQTEVNRELKKLLVASVGDDPQYHFERLAREKNQLILENEALGRNTAQLSEQLERMSIQCDVWRSKFLASRVMADELTNFRVVLQHQNRDAQSAIQDLLSEREQFRQEMISTQKFLEELLVSLQWGREQTYSPNTQPHSTADLALTNHRLAEAVHAHLLGNVGISHPKRTPATAEVCSTPAEKMAEKVLRILDPVACTESSPDNAFAES---TLLTTKKNIGRFHPYTRYENITFNCCSHCQGELLAL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R2X8-1", "uniprot_id": "GO45_MOUSE", "id": "Q8R2X8-1", "name": "Golgin-45", "aln": "MEKMTTLKSSENKGILTSTPIRGAGDGMETEEPPKSVEVTHGVQPINQHVLPSPRKK-------------------VSSDSPGVLQLG---KILNERTVEVEAVRIFVPKAAITHDIPT-KNTKVKSLGHHREELHNQAEVVTDP-----------------------------------------------RKELSEVKKVLEKLKNSERRLLQDKEGLSNQLRVQTEINRELKKLLVASVGDDPQYHFERLAREKNQLILENEALGRNTAQLSEQLERMSIQCDVWRSKFLASRVMADELTNFRVVLQRQNRDAQSAIQDLLSEREQFRQEMTSTQKFLEELLVSLQWGREQTYSPNTQPHSTADLALTNHGLAQAIHAHLLGNVGISHQKKIPTTVEFCSTPAEKMAEKVLRILDPVACTESSPDNQFAESSPTTLLTTKKNIGRFHPYTRYENITFNCCNHCQGELIAL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H2G9-1", "uniprot_id": "GO45_HUMAN", "id": "Q9H2G9-1", "name": "Golgin-45", "aln": "----MTTKNLETKVTVTSSPIRGAGDGMETEEPPKSVEVTSGVQSRKHHSLQSPWKKA------------------VPSESPGVLQLG---KMLTEKAMEVKAVRILVPKAAITHDIPN-KNTKVKSLGHHKGEFLGQSEGVIEP-----------------------------------------------NKELSEVKNVLEKLKNSERRLLQDKEGLSNQLRVQTEVNRELKKLLVASVGDDLQYHFERLAREKNQLILENEALGRNTAQLSEQLERMSIQCDVWRSKFLASRVMADELTNSRAALQRQNRDAHGAIQDLLSEREQFRQEMIATQKLLEELLVSLQWGREQTYSPSVQPHSTAELALTNHKLAKAVNSHLLGNVGINNQKKIPSTVEFCSTPAEKMAETVLRILDPVTCKESSPDNPFFESSPTTLLATKKNIGRFHPYTRYENITFNCCNHCRGELIAL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B8JM41-1", "uniprot_id": "B8JM41_DANRE", "id": "B8JM41-1", "name": "", "aln": "---MMSAELIIKD--VSVVAVRGPGDGMETDKPLPAPEQLT-EAPLQKICSPKHSPR-------------------VATGSPGVLHLG---KVSRDACLELEAVRIVVPRAAIIRTGRSGAHTDDRGSPQHGDEPPPAPPSPPPP-----------------------------------------------AEPLQEYKNSLEKLQSSERRLLQDKEGLSNQLRVQTEVNRELKKLLVASVGDDLQYHFERLAREKNHLILENETLCRNLSHTAEQLERMSIQCDVWRSKFLASRVMAEELTNARSALQRQTRDAQCAIQDLLSEREEFSRDMTHTHRCLEQLLVSLQWGRQQTYYPSAKPLSTGELATANHKLADAINAHLLGKLENSGGKKSPST-EICNTPAEKMAEKVLRSLDPVCVSEQEHDASSSDS---PFLPNRKSIGRFHPYTRYENITFNCCERCHGEIIVL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VHE3-1", "uniprot_id": "Q9VHE3_DROME", "id": "Q9VHE3-1", "name": "Golgin-45", "aln": "----MEANESAMPGTDKSQACRTSGDGMEQPENSGAAKTESEIPASADVDNKVKRPQLSRKDSSVVQEAVMGRKTSTSSGHSSNLPLPGLHTLYRRPENVTRSLAPVVPKGELVQMRPRLVTSADSLPEHKKTKAPKFVPYEPYPGAVNPMISEPTNKHKIHRDKNNLDIAVLVDQVSTLRTQELETETTDIKETDTASSHEVNSLKEELAKMRDERNYFQAQYKFQTQVNSELKSLLVASVGEDLQTRVNLLTEDKLQLARALLDTANNLTTHTEQIEFLAGQCEVWRSKFLASSVMVEELARWKADLTQKNQLLNESTKQLLHATHQIREIQLDMLKQLKFLAKIRFLN-----LPATDVISLSAENLN-------ILQRMVLHTGVGIPEETLKLSSASTSPLCEAEKYAVRALEFISQPLMATDEA--------IRALFDQAQRPHYVQSPASEVTPACDNQQLDKMQ-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . * .***** : : : . . : ..: .. * * .: .:: .**:. : : : :: : * : .: ::.*:.. :: :::: :. * :.**::* ***.*******:* * :.: *:.:* :* .* : :**:* :: **:********* **.:**:. : * ::.: : : ::** .:: . : *: * . * .. * . : ::: : . :. . ..:* : : .:* *: : * : . .. * * . . .*.. : : : ", "identical_positions": 64, "similar_positions": 119, "identity": "13.53%" }, { "cls_id": "homologset.agr.MGI:1201608", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62817-1", "uniprot_id": "HRK_RAT", "id": "P62817-1", "name": "Activator of apoptosis harakiri", "aln": "MCPCPRHRGRGPPAVCGCGDARPGLRWAAAQVTALRLQALGDELHRRAM-RRRARPR-DPLPALLPALRARWPWLCAAAQVAALAAWLLGRRSA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P62816-1", "uniprot_id": "HRK_MOUSE", "id": "P62816-1", "name": "Activator of apoptosis harakiri", "aln": "MCPCPRHRGRGPPAVCGCGDARPGLRWAAAQVTALRLQALGDELHRRAM-RRRARPR-DPLPALLPALRARWPWLCAAAQVAALAAWLLGRRSA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00198-1", "uniprot_id": "HRK_HUMAN", "id": "O00198-1", "name": "Activator of apoptosis harakiri", "aln": "MCPCPLHRGRGPPAVCACSAGRLGLRSSAAQLTAARLKALGDELHQRTMWRRRARSRRAPAPGALPTY---WPWLCAAAQVAALAAWLLGRRNL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***** **********.*. .* *** :***:** **:*******:*:* *****.* * *. **: *********************. ", "identical_positions": 67, "similar_positions": 12, "identity": "71.28%" }, { "cls_id": "homologset.agr.MGI:1201609", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q96MC6-1", "uniprot_id": "S71A1_HUMAN", "id": "Q96MC6-1", "name": "Solute carrier family 71 member 1", "aln": "MTQGKKKKRAANRSIMLAKKIIIKDGGTPQGIGSPSVYHAVIVIFLEFFAWGLLTAPTLVVLHETFPKHTFLMNGLIQGVKGLLSFLSAPLIGALSDVWGRKSFLLLTVFFTCAPIPLMKISPWWYFAVISVSGVFAVTFSVVFAYVADITQEHERSMAYGLVSATFAASLVTSPAIGAYLGRVYGDSLVVVLATAIALLDICFILVAVPESLPEKMRPASW-------------------------------------------------------------------------GAPISWEQADPFASLKKVGQDSIVLLICITVFLSYLPEAGQYSSFFLYLRQIMKFSPESVAAFIAVLGILSIIAQTIVLSLLMRSIGNKNTILLGLGFQILQLAWYGFGSEPWMMWAAGAVAAMSSITFPAVSALVSRTADADQQGVVQGMITGIRGLCNGLGPALYGFIFYIFHVELKELPITGTDLGTNTSPQHHFEQNSIIPGPPFLFGACSVLLALLVALFIPEHTNLSL------RSSSWRKHCGSHSHPHNTQAPGEAKEPLLQDTNV----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P70187-1", "uniprot_id": "S71A1_MOUSE", "id": "P70187-1", "name": "Solute carrier family 71 member 1", "aln": "MTQGKKKKRAANRSIMLAKKIIIKDGGTPQGIGSPSVYHAVIVIFLEFFAWGLLTAPTLVVLHETFPKHTFLMNGLIQGVKGLLSFLSAPLIGALSDVWGRKSFLLLTVFFTCAPIPLMKISPWWYFAVISVSGVFAVTFSVVFAYVADITQEHERSMAYGLVSATFAASLVTSPAIGAYLGRVYGDSLVVVLATAIALLDICFILVAVPESLPEKMRPASW-------------------------------------------------------------------------GAPISWEQADPFASLKKVGQDSIVLLICITVFLSYLPEAGQYSSFFLYLRQIMKFSPESVAAFIAVLGILSIIAQTIVLSLLMRSIGNKNTILLGLGFQILQLAWYGFGSEPWMMWAAGAVAAMSSITFPAVSALVSRTADADQQGVVQGMITGIRGLCNGLGPALYGFIFYIFHVELKELPITGTDLGTNTSPQHHFEQNSIIPGPPFLFGACSVLLALLVALFIPEHTNLSL------RSSSWRKHCGSHSHPHSTQAPGEAKEPLLQDTNV----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q1LV45-1", "uniprot_id": "Q1LV45_DANRE", "id": "Q1LV45-1", "name": "Solute carrier family 71 member 1", "aln": "MTQ--KKKKRVNRSLLLAKKIIIKDGGTPQGFGSPSVYHAVIVIFLEFFAWGLLTAPTLGALDETFPKHTFLMNGLIQGVKGLLSFLSAPLIGALSDVWGRKSFLLLTVFFTCAPIPLMKISPWWYFAMISVSGVFAVTFSVIFAYVADITQEHERSMAYGMVSATFAASLVISPAIGAYLSHVYGDTLVVVLASAIAMLDICFILVAVPESLPEKMRPASW-------------------------------------------------------------------------GAPISWEQADPFASLRKVGQDSTVLLICITVFLSYLPEAGQNSSFFLYLQQIMGFSSESVAAFIAVLGLLSVVAQTVVLSLLMRSIGNKNTILLGLGFQILQLAWYGFGSEPWMMWAAGAVAAMSSITFPAVSALISRTADPDQQGVGQGMVTGIRGLCNGLGPALYGFIFYIFHVELDKVPEKGPDVQHHR---DLHQQSAIIPGPPFLFGACSVLLALLVALFIPEHPHMGT------RSGSWKHHTSPHGHPHSPHPPGEAKEPLLQDTNV----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VPD8-1", "uniprot_id": "Q9VPD8_DROME", "id": "Q9VPD8-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "------------MSKFGLKKLLVSLAST-SGIGKPSVGHILVVVFLEYFAWGLLTMPMIATLKETFPDHTFLMNGLVMGVKGILSFLSSPLIGALSDIYGRKVLLLITVIFTSLPIPMMTMDNWWFFVISSISGVLGVSFSVAFAYVADVTTKEERSRSYELVSATFAASLVIAPAMGNLIMDRYGINTVVLVATLVSTTNVMFVLLAVPETLQQNVR-----------------------------------------------------------------------------STGLSWKQADPFLSLRRVGSDPNVLLLCVVMFTFLLPEAGEYSSVPAYLKLTMGFDFTELSTLVAFMAILGISIN-VTLGSIVKTLGAKNAIILGLLLELLQLILFAIGYEKWQMWLAGNVAALSSITFPAVSAYVSLYTDVETQGAVQGMITGMSGLCSGLGPALFGIVFYLSDMDLDKNRILIGSVSGDR---------TVTN--PFMIGAISVFIGILLASYIPDEK----------VSRGRREEFSALKY----------IIEMEEATTI----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VPE0-1", "uniprot_id": "Q9VPE0_DROME", "id": "Q9VPE0-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "------------MAQLKFLRPLVKVLVNRSGIGKASVWHAVIVTFMHYFSWGLLTVPFIEKLSGSFGNRVLLVDGLVYGVRGILGFVTTPVMGAISDFHGRKVVMLLAVATTYAPIPFMMLKSWWFFAILTVSSICGSTYSSSLAYVADTTTVENRSKGYGIVAASFGAGIAFSPSLGNYLMKSYGSASVILIAAITGLINIMFIIFAVPESLVLKEKNNMLDEESDN-----KMEDINPKERKEILNREEKLNNHVSANKSNHGTSQNLVTNKELGQQFNKEENLQNDLTEKEKIDNGSLNSSDLWEVLRKSRKDKNLLVIYLITFLSIWPFAGVDSTAPVYLKTNMGFEYEEVSMMLGLLSVLAITSN-LLLGYIINIVGAKWSIRLGLLLLLLQLFFFGFGTHHWMYWLSSILAALATIIPAANNAVASIYASPDNRGAVLGIISGIECLSEGVGPAFFGVLFFIFQDDSKN--KVNSPIS-----------------MPFVISAIGVFVAIVLTGFIKKETVEKAPLIYKIIDDASEDEVEPLAKTTFKYEKNNGYVKLEIDDNYDSDCKEHSFK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VPD9-1", "uniprot_id": "Q9VPD9_DROME", "id": "Q9VPD9-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "------------MAQLKFLRPLVKVLVNRSGIGKASVWHAVIVTFMHYFSWGLLTVPFIEKLSGSFGNRVLLVDGLVYGVRGILGFVTTPVMGAISDFHGRKVVMLLAVATTYAPIPFMMLKSWWFFAILTVSSICGSTYSSSLAYVADTTTVENRSKGYGFVAASFGAGIAFSPSLGNYLMKSYGSASVILIATITGMINILFIIFAVPESLVLKEKKVILNENNDNKVEDTKVDDISPKEKKENLNGEGKVN--VEVNKP---TSQNIVTNKELDQQFSKEENLQNDLTEKEKIDNGSLNSSDLWEVLRKSRKDKNLLVIYLITFLSIWPFAGVDSTAPVYLKTNMGFEYEEVSMMLGLLSVLAITSN-ILLGYIMNIVGAKWSIRLGLLLLFLQMLFFGFGTHHWMYWLSSILAALATIIPAANNAVASIYASPDNRGAVLGIISGIECLSEGVGPAFFGLLFFIFQDDSETDLKVNSPIS-----------------MPFVISAISVFVAIVLSSFIKKDTLGNE-------ETRVANENIP---------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : ::. . .*:*..** * ::* *:.:*:***** * : * :* .:.:*::**: **:*:*.*:::*::**:**. *** .:*::* * ***:* :. **:*.: ::*.: . ::* :***** * .:** .* :*:*:*.*.:. :*::* : ** *:::*: . :: *::.****:* : : * :.:* : *:: .* :*:: : * * ** *: **: * *. .:: ::..:.:*.: : : *. ::. :* * :* *** : :**: :.:* . * * :. :**:::* .* .* * :. : :*. *:::*: *..*:***::*.:*:: . : . : **::.* .*::.:::: :* .. . .. . ", "identical_positions": 117, "similar_positions": 170, "identity": "20.21%" }, { "cls_id": "homologset.agr.MGI:1201610", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K5Y3-1", "uniprot_id": "A0A0G2K5Y3_RAT", "id": "A0A0G2K5Y3-1", "name": "", "aln": "MQKAGLGGDRKVCPLARGCPRPENSRGKMCCYHGNRIAPGQVKMAGRSVGVPRRGAAGP------QSRGQLAAGR-----DLLAREQEYKRLNAELEAKTANLVRQAEEVIREQQEERARPFSALTTSCKEEDGYGPRDLLSSEGMAHPWSETKPKTKNTGPVNKIQNRLHSADKERKINSSVKLKYPDVQTA-NDVAIPDDFSDFSLAKTISRIEGQLEEDVLPECADDDSFCGVSKDIGTEAQIRFLKAKLHVMQEELDSVVCECNKKEDEIQDLKSKVKNLEEDCVRQQRTVTSQQTQIEKYRNLFEEANKRCDELQQQLSSVDRELENKRRLQKQAATSQSATEVRLNRALEEAEKYKAELSKLRQTNKDITNEDHQKIEVLKSENKKLERQKGELMIGFKKQLKLIDILKRQKMHIEAAKMLSFSEEEFMKALEWGSS--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D845-1", "uniprot_id": "TEX9_MOUSE", "id": "Q9D845-1", "name": "Testis-expressed protein 9", "aln": "-------------------------------------------MAGRSVRVPRRGSAGT------QSRGQLAAGR-----DLLAREQEYKRLNEELEAKTADLVRQAEEVIREQQEVRARPFSALTTSCKEEGGSSSRDLLSSEG-THPWTETKPKTKNTGPVNKIQNRLHSADKERKTNSSAKLKYPDAQTA-NDVAIPDDFSDFSLAKTISRIEGQLDEDGLPECAEDDSFCGVSKDIGTEAQIRFLKAKLHVMQEELDSVVCECSKKEDKIQDLKSKVKNLEEDCVRQQRTVTSQQSQIEKYKNLFEEANKKCDELQQQLSSVERELESKRRLQKQAASSQSATEVRLNRALEEAEKYKVELSKLRQTNKDITNEDHQKIEVLKSENKKLERQKGELMIGFKKQLKLIDILKRQKMHIEAAKMLSFSEEEFMKALEWGSS--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N6V9-1", "uniprot_id": "TEX9_HUMAN", "id": "Q8N6V9-1", "name": "Testis-expressed protein 9", "aln": "-------------------------------------------MAGRSLCLTRSSVPGTPFPP--PVQQPSTPGP-----DLLALEEEYKRLNAELQAKTADVVQQAKEIIRDRQEVRSRPVSTQMKSCDDEDDYSLRGLLPSEGIVHLHSETKPKTKNIDPVNKVQNKLHSANKGRKTNSSVKLKYSDVQTA-DDVAIPEDFSDFSLAKTISKIEGQLEEEGLPEYIDD-IFSGVSNDIGTEAQIRFLKAKLHVMQEELDNVVCECNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVEKYKTLFEEANKKYDGLQQQLSSVERELENKRRLQKQAASSQSATEVRLNRALEEAEKYKLELSKLRQNNKDIANEEHKKIEVLKSENKKLEKQKGELMIGFKKQLKLIDVLKRQKMHIEAAKMLSFTEEEFMKALEWGNS--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QU49-1", "uniprot_id": "F1QU49_DANRE", "id": "F1QU49-1", "name": "", "aln": "------------------------------------MADSTPRPALRPFKKPQTSYSERPSSTNLQSRTSSAPLKKPPQMDLLAKEEEYKRLNAKLEAKTAEIVRDAEKIMRDQNEVLSKPIFTCISIDSDSD-------LEVPGKPDVKKEPTSKQPTMMIMKNKSISAKSSKPSKPSSGNRKIQQKAPQTAVDDVAIPEDFGDFSLAKTISKIEDRVGDDLTEEHLQDDIMPSAGDEMGAEAQIRFLKAKLRVMQEELNRLSYACNKKDDENSTLTSKLKDLEEERARLQRTTNIQQTQVEKQKALAEESSRKSEGLQQQMAALQKELESMKRTFKQAASTHSATEVRLNRALEEAEKTKTQLNKLKQSTKDLSSQEHQKIEALQAENRKLERQKAELIVGFKKQLKLIDILKRQKMHYEAAKLLSFTEEEFMKALDWGKEVL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W144-1", "uniprot_id": "Q9W144_DROME", "id": "Q9W144-1", "name": "Testis expressed 9", "aln": "----------------------------------------MAELLSREKELFKINQELN--------LLTLSPAA-----DAMYPAKGSSKSTAVAVPRFATFQKQKGPSSLLRKKGAPTACTKAAPKASPGRETVPTARSPMPDMSLLTK-SKPAAGPTSPTPRNLSKFSTFTKDVSSKTATYVKYRNPNFS--ESPSLDELLRNDADEANRKPDVVEVEVTQKRESTTVVNGQLKKQVTKDNFIKFLKAKVAILEEDHAQHAGELIRQKEQLEHALEAQRKSEHQRDQAINSNKHLSEQLMRSERQCEGFNQRQKEQQLEFITQQRELEVLKRDAKVSRQTNINLENRLSRVQEDADAARQELKLLREEQRDQLEAHRKELKLRDSRIRALKRQRGDLLNAYKKQLYMIDNLKRQTICLEQSAAIGFGEKEFNKVLDWNAKT-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : . :. * : : .: . .: * . :: ::: . . . . . ... . : . :: : : : . ::: . :: : : : . .:: : *:*****: :::*: ::.:: . . :. *.: : .: . . *: : . * .:: . * :: : ::*** :* * : :: * **.*. *:*: : :*. *:: :* . .::::: .:. : *::*:.:*: .:**** :** ****.: * : :.* *:** *.*:*. . ", "identical_positions": 49, "similar_positions": 126, "identity": "11.01%" }, { "cls_id": "homologset.agr.MGI:1201670", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35226-1", "uniprot_id": "PSMD4_MOUSE", "id": "O35226-1", "name": "26S proteasome non-ATPase regulatory subunit 4", "aln": "MVLESTMVCVDNSEYMRNGDFLPTRLQAQQDAVNIVCHSKTRSNPENNVGLIT-LANDCEVLTTLTPDTGRILSKLHTVQPKGKITFCTGIRVAHLALKHRQGKNHKMRIIAFVGSPVEDNEKDLVKLAKRLKKEKVNVDIINFGEEEVNTEKLTAFVNTLNGKDGTGSHLVTVPPGP-SLADALISSPILAGE-GGAMLGLGAS---------DFEFGVDPSADPELALALRVSMEEQRQRQEEEARRAAAASAAEAG----------------IATPGTE---DSDDALLKMTINQ-QEFGRPGLPDLSSMTEEEQIAYAMQMSLQGTEFSQ-ESADMDASSAMDTSDPVKEEDDY-DVMQDPEFLQSVLENLPGVDPNNAAIRSVMGALASQATKDGKNDKKEEEKK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P55036-1", "uniprot_id": "PSMD4_HUMAN", "id": "P55036-1", "name": "26S proteasome non-ATPase regulatory subunit 4", "aln": "MVLESTMVCVDNSEYMRNGDFLPTRLQAQQDAVNIVCHSKTRSNPENNVGLIT-LANDCEVLTTLTPDTGRILSKLHTVQPKGKITFCTGIRVAHLALKHRQGKNHKMRIIAFVGSPVEDNEKDLVKLAKRLKKEKVNVDIINFGEEEVNTEKLTAFVNTLNGKDGTGSHLVTVPPGP-SLADALISSPILAGE-GGAMLGLGAS---------DFEFGVDPSADPELALALRVSMEEQRQRQEEEARRAAAASAAEAG----------------IATTGTE---DSDDALLKMTISQ-QEFGRTGLPDLSSMTEEEQIAYAMQMSLQGAEFGQAESADIDASSAMDTSEPAKEEDDY-DVMQDPEFLQSVLENLPGVDPNNEAIRNAMGSLASQATKDGKKDKKEEDKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P55035-1", "uniprot_id": "PSMD4_DROME", "id": "P55035-1", "name": "26S proteasome non-ATPase regulatory subunit 4", "aln": "MVLESTMICFDNSDFQRNGDYFPTRLIVQRDGINLVCLTKLRSNPENNVGLMT-LSNTVEVLATLTSDAGRIFSKMHLVQPKGEINLLTGIRIAHLVLKHRQGKNHKMRIVVFVGSPINHEEGDLVKQAKRLKKEKVNVDIVSFGDHGNNNEILTAFINALNGKDGTGSHLVSVPRGS-VLSDALLSSPIIQGEDGMGGAGLGGN---------VFEFGVDPNEDPELALALRVSMEEQRQRQESEQRRANPDGAPPTGGDAGGGGGVSGSGPGNEESAGAENEANTEEAMLQRALALSTETPEDNLPDFANMTEEEQIAFAMQMSMQDAPDDS-VTQQAKRPKTDEANAPMDVDEDYSEVIGDPAFLQSVLENLPGVDPQSEAVRDAVGSLN--KDKDKKSDGKDSQKK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38886-1", "uniprot_id": "RPN10_YEAST", "id": "P38886-1", "name": "26S proteasome regulatory subunit RPN10", "aln": "MVLEATVLVIDNSEYSRNGDFPRTRFEAQIDSVEFIFQAKRNSNPENTVGLISGAGANPRVLSTFTAEFGKILAGLHDTQIEGKLHMATALQIAQLTLKHRQNKVQHQRIVAFVCSPISDSRDELIRLAKTLKKNNVAVDIINFGEIEQNTELLDEFIAAVNNPQEETSHLLTVTPGPRLLYENIASSPIILEEGSSGMGAFGGSGGDSDANGTFMDFGVDPSMDPELAMALRLSMEEEQQRQERLRQQQQ----------------------------------------------------QQDQPEQSEQPEQHQDK------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****:*:: .***:: ****: **: .* *.:::: :* .*****.***:: . .**:*:*.: *:*:: :* .* :*:: : *.:::*:*.*****.* :: **:.** **:.... :*:: ** ***::* ***:.**: *.* * *: ::*. : ***::*. *. * : : ****: * . . .:*.. ::*****. *****:***:****::**** :: . . *: :. .*:.* ", "identical_positions": 102, "similar_positions": 94, "identity": "24.88%" }, { "cls_id": "homologset.agr.MGI:1201671", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D2G5-1", "uniprot_id": "SYNJ2_MOUSE", "id": "Q9D2G5-1", "name": "Polyphosphatidylinositol phosphatase SYNJ2", "aln": "MALSKGLRLLARLDPTGPSSVLLEARGRGDC---------LLFEAGAVATLAPEEKEV-IKGLYSKLTDAYGCLGELRLQSGGVPLSFLVLVTGCMSVGR----------IPDAEIYKITATELYPLQ--------------------------------------------------EEAKEEDRLPTLKKILSSGVFYFAWPNDGACFDLTIRAQK-QGDDGSEWGTSFFWNQLLHVPLR----------QHQVNCHNWLLKVICGVVTIRTVYASHKQAKACLISRISCERAGARFLTRGVNDDGHVSNFVETEQTIYMDDGVSSFVQIRGSVPLFWE-QPGLQVGSHHLRLHRGLEANAPAFERHMVLLKEQYGKQVVVNLLGSRG-GEEVLNRAFKKLLWAS---CHAGDTPMINFDFHQFAKGRKLEKLENLLRPQLQLHWED-FGVFAKGENVSPRFQKGTLRMNCLDCLDRTNTVQCFIALEVLHLQLESLGLNSKP---IIDRFVESFKAMWSLNGHSLSKVFTGSRALEG-------KAKVGKLKDGARSMSRTIQSNFFDGVKQEAIKLLLVGDVYNEESTDKGRMLLDNTALL-----------------ATPRILKAMTERQSEFTNFKRIQIAVGTWNVNGGKQFRSNLLGTAELTDWLLDAPQLSGAVDSQDDGSPADVFAIGFEEMVELSAGNIVNASTTNRKMWGEQLQKAISR---SHRYILLTSAQLVGVCLYIFVRPYHVPFIRDVAIDTVKTGMGGKAGNKGAVGIRFQLHSTSFCFVCSHLTAGQSQVKERNEDYREITHKLSFPSGRNIFSHDYVFWCGDFNYRIDLTYEEVFYFVKRQD---WKKLMEFDQLQLQKSSGKIFKDFHEGAVNFGPTYKYDVGSAAYDTSDKCRTPAWTDRVLWWRKKHPYDKTAGELNLLDSDLDGDPQIRHTWSPGTLKYYGRAELQASDHRPVLAIVEVEVQEVDVGARERVFQEVSSVQGPLDATVVVNLQSPTLEEKNEFPEDLRTELMQTLGNYGTIILVRINQGQMLVTFADSHSALSVLDVDGMKVKGRAVKIRPKTKDWLEGLREELLRKRDSMAPVSPTANSCLLEENFDFSSLDYESEGDVLEEDEDYLVDGFGQPVVSDSELGGDNSSDT--MSSLTPASKSPALAKKKQHPTYK---------------------------------------------AGLMVKKSASDASISSGTHGQYSILQTAKLLPGAPQQPPKARTGISKPYNVKQIKTTNAQEAEAAIRCLLEASGGVPESAPGAIPLR----------NQGSSKPEATLGPPALPRRPAPRVPTMKKPTLRRTGKPMLPEENFEPQPVHFTMASQEMNLETPPPITATPIPPVPKPRTLQPGKGVEGRPSSGKPEPDEAPSVTGTVESPPPEAQEAPSLAPKVPPRRKKSAPAAFHLQVLQNNSQVLQGLTCSSS-SPPSLKPDTHPLCLQ-VALGTSSARSPETHGPRVTEPEAASFHGNYPDPFWSLLHHPKLLNN-TWLSKSSEPLDVGSRNPERTHTEPAQVNASLAERGLPPDHGGKDLSHWVTASNKDKRTTLGV-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O55207-1", "uniprot_id": "SYNJ2_RAT", "id": "O55207-1", "name": "Polyphosphatidylinositol phosphatase SYNJ2", "aln": "MALSKGLRLLARLDPTGPSSVLLEARGRGDC---------LLFEAGAVATLAPEEKEV-IKGLYGKPTDAYGCLGELSLKSGGVPLSFLVLVTGCTSVGR----------IPDAEIYKITGTEFYPLQ--------------------------------------------------EEAKEEDRLPALKKILSSGVFYFAWPNDGACFDLTIRAQK-QGDDCSEWGTSFFWNQLLHVPLR----------QHQVNCHDWLLKVICGVVTIRTVYASHKQAKACLISRISCERAGARFLTRGVNDDGHVSNFVETEQAIYMDDGVSSFVQIRGSVPLFWE-QPGLQVGSHHLRLHRGLEANAPAFERHMVLLKEQYGQQVVVNLLGSRG-GEEVLNRAFKKLLWAS---CHAGDTPMINFDFHQFAKGRKLEKLENLLRPQLKLHWDD-FGVFAKGENVSPRFQKGTLRMNCLDCLDRTNTVQCFIALEVLHLQLESLGLNSKP---ITDRFVESFKAMWSLNGHGLSKVFTGSRALEG-------KAKVGKLKDGARSMSRTIQSNFFDGVKQEAIKLLLVGDVYNEESTDKGRMLLDNTALLGLGSNKQNSLSGMLDGKATPRILKAMTERQSEFTNFKRIQIAMGTWNVNGGKQFRSNLLGTTELTDWLLDAPQLSGAVDSQDDGGPADIFAVGFEEMVELSAGNIVNASTTNRKMWGEQLQKAISR---SHRYILLTSAQLVGVCLYIFVRPYHVPFIRDVAIDTVKTGMGGKAGNKGAVGIRFQFHSTSFCFICSHLTAGQSQVKERNEDYREITHKLSFPSGRNIFSHDYVFWCGDFNYRIDLTYEEVFYFVKRQD---WKKLMEFDQLQLQKSSGKIFKDFHEGTINFGPTYKYDVGSAAYDTSDKCRTPAWTDRVLWWRKKHPYDKTAGELNLLDSDLDGDANIRHTWSPGTLKYYGRAELQASDHRPVLAIVEVEVQEVDVGARERVFQEVSSVQGPLDATVIVNLQSPTLEERNEFPEDLRTELMQTLGNYGTIILVRINQGQMLVTFADSHSALSVLDVDGMKVKGRAVKIRPKTKDWLEGLREELIRKRDSMAPVSPTANSCLLEENFDFTSLDYESEGDVLEDDEDYLADEFGQPVVSDSELGGDDSSDT--MSASTPASKSPALAKKKQHPTYKDDADLMTLKLELEVAGNFRHRSPSRSLSVPNRPRPPHPPQRPPPPTGLMVKKSASDASISSGTHGQYSILQTAKLLPGAPQQPPKARTGISKPYNVKQIKTTNAQEAEAAIRCLLEAGGGVPESAPGATPLR----------NQGSSKPEASLGPPVLPRRPVPRVPTMKKPTLRRTGKPMLPEEQCEQQPVHFTMASQEMNLETPPPITA-PIPPVPKPRTFQPGRGVERRPSGGKPEPDDAPPVTGAVELSSPEAPEAPSLAPKVPPRRKKSAPAAFHLQVLQSNSQLLQGLTCSSS-SPSPPKPDTPLLYPQ-MALGTSSAISPETDGPRVTEPEAASFHGDYPDPFWSLLHHPKLLNNNTWLSKSSEPLDLGSRTPERTHTDSAQVNASVVERGLPPDHGGKDFSHWMAASNKDKRTTLGV-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O15056-1", "uniprot_id": "SYNJ2_HUMAN", "id": "O15056-1", "name": "Polyphosphatidylinositol phosphatase SYNJ2", "aln": "MALSKGLRLLGRLGAEGDCSVLLEARGRDDC---------LLFEAGTVATLAPEEKEV-IKGQYGKLTDAYGCLGELRLKSGGTSLSFLVLVTGCTSVGR----------IPDAEIYKITATDFYPLQ--------------------------------------------------EEAKEEERLIALKKILSSGVFYFSWPNDGSRFDLTVRTQK-QGDDSSEWGNSFFWNQLLHVPLR----------QHQVSCCDWLLKIICGVVTIRTVYASHKQAKACLVSRVSCERTGTRFHTRGVNDDGHVSNFVETEQMIYMDDGVSSFVQIRGSVPLFWE-QPGLQVGSHHLRLHRGLEANAPAFDRHMVLLKEQYGQQVVVNLLGSRG-GEEVLNRAFKKLLWAS---CHAGDTPMINFDFHQFAKGGKLEKLETLLRPQLKLHWED-FDVFTKGENVSPRFQKGTLRMNCLDCLDRTNTVQSFIALEVLHLQLKTLGLSSKP---IVDRFVESFKAMWSLNGHSLSKVFTGSRALEG-------KAKVGKLKDGARSMSRTIQSNFFDGVKQEAIKLLLVGDVYGEEVADKGGMLLDSTALL-----------------VTPRILKAMTERQSEFTNFKRIRIAMGTWNVNGGKQFRSNVLRTAELTDWLLDSPQLSGATDSQDDSSPADIFAVGFEEMVELSAGNIVNASTTNKKMWGEQLQKAISR---SHRYILLTSAQLVGVCLYIFVRPYHVPFIRDVAIDTVKTGMGGKAGNKGAVGIRFQFHSTSFCFICSHLTAGQSQVKERNEDYKEITQKLCFPMGRNVFSHDYVFWCGDFNYRIDLTYEEVFYFVKRQD---WKKLLEFDQLQLQKSSGKIFKDFHEGAINFGPTYKYDVGSAAYDTSDKCRTPAWTDRVLWWRKKHPFDKTAGELNLLDSDLDVDTKVRHTWSPGALQYYGRAELQASDHRPVLAIVEVEVQEVDVGARERVFQEVSSFQGPLDATVVVNLQSPTLEEKNEFPEDLRTELMQTLGSYGTIVLVRINQGQMLVTFADSHSALSVLDVDGMKVKGRAVKIRPKTKDWLKGLREEIIRKRDSMAPVSPTANSCLLEENFDFTSLDYESEGDILEDDEDYLVDEFNQPGVSDSELGGDDLSDVPGPTALAPPSKSPALTKKKQHPTYKDDADLVELKRELEAVGEFRHRSPSRSLSVPNRPRPPQPPQRPPPPTGLMVKKSASDASISSGTHGQYSILQTARLLPGAPQQPPKARTGISKPYNVKQIKTTNAQEAEAAIRCLLEARGGASEEALSAVAPRDLEASSEPEPTPGAAKPETPQAPPLLPRRPPPRVPAIKKPTLRRTGKPLSPEEQFEQQTVHFTIGPPETSVEAPPVVTAPRVPPVPKPRTFQPGKAAE-RPSHRKPASDEAPPGAGASVPPP---LEAPPLVPKVPPRRKKSAPAAFHLQVLQSNSQLLQGLTYNSSDSPSGHPPAAGTVFPQGDFLSTSSATSPDSDGTKAMKPEAAPLLGDYQDPFWNLLHHPKLLNN-TWLSKSSDPLDSGTRSPKRDPIDPVSAGASAAKAELPPDHEHKTLGHWVTISDQEKRTALQVFDPLAKT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P50942-1", "uniprot_id": "INP52_YEAST", "id": "P50942-1", "name": "Polyphosphatidylinositol phosphatase INP52", "aln": "MKILLSKQQTRKIAIVSETHGLVFRPINSKN---------SRRSTCAVELVPKAELNG-NGFRRLSNHEIYGFIGLIEIEG----LMFIATITGKSKVAQP---------IPNKTVNKIYAVDFFCLNNSKWDFMDIDSSGYPIVTNDGDFAISSPPSISTHSSRSSLRSSSSRSLNAQEQAPKHPCHELRKLLSNGSFYYSTDFDLTCTLQKRGFTE-HSLSFDDFDREFMWNSFLMDEIITYRDRLDVTAKELLDQRGFLTTVIRGFAETIFSYINRLKVGLTIISRQSWKRAGTRFNARGIDDDGHVANFVETEMIMYSSQYCYAFTQIRGSLPIFWE-QDTSLIS-PKIQITRSVEATQPTFDEHFIRLFKKYGPVHIINLLSTKS-SEIQLSRRYKEQLKNSEKMKIGRDVFLTSFDFHRETSQDGFAAASRIIPKIRNTILDAGYFSYDVKEGRLISEQDGVFRTNCLDCLDRTNLIQQTISLAVFKLFLEDFRLVKPSSFIDDNEFVQKVNALWADNGDQISQIYTGTNALKSSYSRKGKMSFSGALSDATKSVSRMYINNFVDKGKQQNIDTLLGKLPHQQVVELYDP--------------------------ICEYVNERLLESEEKFTTHSNINLFVGTFNVNGNS-------RRADLSKWLFPIG----------DKFKPDVVVLGLQEVIELTAGSILNADYTKSSFWETMVTDCLNQY--EEKYLLLRVEQMSSLLILFFARSDRAYNIKEVGGSTKKTGFGGITGNKGAVAIRFDYGATSFCFVNTHLSAGASNIDERRNDYNNIYRNITFPRSKTIPHHDSLFWLGDLNYRITLTNDEVRRELRAQKDGYIDRLLQYDQLTQEINEGVVFQGFKEPTLQFRPTYKYDYGTDNYDTSEKARTPSWTDRIIYKGENLHP-----------------------------LAYSDAPLKISDHKPVYAAYRANVKFVDE-----------KEKLNLVEKLYAEYKNTHPEALTTGPDELSHARME------------KQKESIPLDATVQSAGIKLIDLDDTSSCVSPLLSGPSPQPSVVGP-------------------------------------------------------------------------------------------------------------------------------------------------------GGLSNVSPDKSKLNVLPPPPPTSRHNKEPSSK-LLSPTKEISIVSVSPRKGESNL-------------------------------------PALERHSTPKPLPPVPALSLSKPVSLQKSSSELQHAK------------------------------ETIDNGKIVPRPCPPIRRKSSTAPDEISTSTKNSGVSTTEDPE-PAKASTKPEKPPVVKKPHYLSVAANKLNTSQEHSIKVSPS------------------------------------------------------------------NSKSEEELPCKKKSKPKVPAKNPELEKLSVHPLKPCDPN----------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q12271-1", "uniprot_id": "INP53_YEAST", "id": "Q12271-1", "name": "Polyphosphatidylinositol phosphatase INP53", "aln": "MIIFVSEEPERRLAIVSNLYALVLKPVGKKP---------SDKPLCAIELLQKNDLKK-YGFKRLTSHEIFGVIGLIEVNG----LLFVGAITGKSKVAQP---------CPGETVNKIFAVDFFCLNDNSWDFIEIDSSGYPVLP-------------------------ETASTEYQDALPKHPCYELKKLLSNGSFYYSSDFDLTSTLQHRGYGQ-HSLSTDTYEEEYMWNSFLMQEMITYRDHLDTNLKQILDDEGFLTTVIRGFAETFVSYVKKLKVALTIISKQSWKRAGTRFNARGVDDEANVANFVETEFIMYSSQYCYAFTQIRGSIPVFWE-QGTSLIN-PRVQITRSFEATQPVFDKHIMKSVEKYGPVHVVNLLSTKS-SEIELSKRYKEHLTHSKKLNFNKDIFLTEFDFHKETSQEGFSGVRKLIPLILDSLLSSGYYSYDVREKKNISEQHGIFRTNCLDCLDRTNLAQQIISLAAFRTFLEDFRLISSNSFIDDDDFVSKHNTLWADHGDQISQIYTGTNALKSSFSRKGKMSLAGALSDATKSVSRIYINNFMDKEKQQNIDTLLGRLPYQKAVQLYDP--------------------------VNEYVSTKLQSMSDKFTSTSNINLLIGSFNVNGAT-------KKVDLSKWLFPIG----------EKFKPDIVVLGLQEVIELSAGSILNADYSKSSFWENLVGDCLNQY--DDKYLLLRVEQMTSLLILFFVKADKAKYVKQVEGATKKTGFRGMAGNKGAVSIRFEYGATSFCFVNSHLAAGATNVEERRSDYESIVRGITFTRTKMIPHHDSIFWLGDMNYRINLPNEDVRRELLNQEEGYIDKLLHFDQLTLGINSGSVFEGFKEPTLKFRPTYKYDPGTGTYDSSEKERTPSWTDRIIYKGENLLP-----------------------------LSYSDAPIMISDHRPVYAAYRAKITFVDD-----------KERLSLKKRLFTEYKQEHPEE----PGSLISDLLS------------LDLDNKSTDGFKSSSESSLLDID-------PIMAQPTAS-SVASS-------------------------------------------------------------------------------------------------------------------------------------------------------SPVSSASAS-----LQPVRTQNSSQSRTPIKKPVLRPPPPPAHKSVSAP-----------------------------------------------APSTSKEKSPTPQTSTASLSSVTKN---IQENK------------------------------PLAQNRRIPP---PGFSQNILTP---KSTSNLASPMSSKVDLYNSASESTRSAQDARQQTPTAFAASR---------DVNGQPE------------------------------------------------------------------ALLGDE--------NPIEPEEKAKLNHMTLDSWQPLTPK----------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P40559-1", "uniprot_id": "INP51_YEAST", "id": "P40559-1", "name": "Phosphatidylinositol 4,5-bisphosphate 5-phosphatase INP51", "aln": "MRLFIGRR-SRSIVISSNNYCLSFQRLRSIPGASSQQRQLSKTPSVTIKSYPDTDLSSDSNYLEVKSCIFNGLLGLVCLNG----DIYVAVISGVQNVGFPRWKLIDHQVRPSESIYKVLDVDFYSLENDVFDYLLCERS----------------------------------EQNYDKLIHEHPCGPLKKLFSDGTFYYSRDFDISNIVKNHGLSHNLEYTVDNQDLSFIWNANLASEVINWRSKISNEEKQLFANAGFLTFVIRGYCKTALIEDGPNTASITIISRISTESKQDTLELEGISEDGRVSLFVETEIVVTTEKFIFSYTQVNGSIPLFWESVESQLLYGKKIKVTKDSIEAQGAFDRHFDNLTSKYGVVSIVNIIKPKSESQEKLALTYKDCAESK----------GIKITNIEYSSSVLTKSPHKLLYLLKQDIYEFGAFAYDISRGIYFAKQTGVLRISAFDSIEKPNTVERLVSKEVLELTTNEIDVFELT-----SPFLDAHDKLWSENYYWLDRTYTKHTKNSG--------KYTKVYSKLFGSRVRLYDP-------------------------------------------------------LHIYISQYLKQLRSKYTFEKDISIFAGTFNISGKIP-------KDDIKDWIFPKSMS-------KEDEMADLYVIGLEEVVELTPGHMLATDPYVRQFWEKKILTLLNGPGRKKKYIRLWSTQLGGILLLLFMNETEYSKVKHIEGDVKKTGFGGMASNKGAVAVSFKYSATRFCVLVSHLAAGLENVEQRHNDYKTIAKSIRFSKGLRIKDHDAIIWMGDFNYRILMSNEDVRRKIVSKEY---ASLFEKDQLNQQMIAGESFPYFHEMAIDFPPTYKFDPGTKNYDTSEKMRIPAWTDRILSRGEVLEQ----------------------------LEYKCCEDILFSDHRPVYAIFRARVTVVDE---------------QKKTTLGTQIYEKIMERLEGLDDDEKIAVLS--------------DDAFVIESFEGSD--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SIAGPTHSPTPIPEPKRGRKLPPPSSDLKKWWIGSGKQVKVVLDVDPA-----------------------------------------------VYMINPKRDPNPFVENEDEPLFIER---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : . . : . * :: : . . * :* : ::. :: ::* .*. *. : *: .::: *: :. :. *:*::*.* **:: * : . . .::** * : :. . .:* :* * . ::*: * : : .*:.::..*: ***** : .. ::.*:.**:*:*** : :::: :. .*:.*: .:** ::*:: .:. .: * :*. . .: . :. :: . . : . * * :* ..:*.:::.* : :: .:. : : : . . *:. . :*: : :.: :* .. .. * * : : . .::* . * : *::*:.* ::..*:: : .*: .:*::*::**:.* :: :. .:* : :. ..:*: * *: .: : :* . . ::.: . ***: * :.*****.: *. :* **.: :**:** ::.:*..**. * : : *. : ** ::* **:**** :. ::* : :. *:. *** * * *:* ::.* ****:* *: **:*:* * *:****:: : : ***:** * ...: ** : .: . * . :. ::. : . . . : ... * * . . . ", "identical_positions": 140, "similar_positions": 273, "identity": "8.64%" }, { "cls_id": "homologset.agr.MGI:1201673", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O60902-1", "uniprot_id": "SHOX2_HUMAN", "id": "O60902-1", "name": "Short stature homeobox protein 2", "aln": "MEELTAFVSKSFDQ--------------------KVKEKKEAITYREVLESGPLRG----AKEPTGCTEAGRDDRSSPAVRAAGGGGG-GGGGGGGGGGGGGVGGGGAGGGAGGGRSP----VRELDMG---------------AAERSREPGSPRLT---------EVSPELKDRKEDAKGMEDEGQTKIKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQLHKGVLIG-----AASQFEACRVAPYVNVGALR---MPFQQDSHCNVTPLSFQVQAQ------LQLDSAVAH-------AHHHLHPHLAAHAPYMMFPAPPFGLPLATLAADSASAAS----------VVAAAAAAKTTSKNSSIADLRLKAKKHAAALGL------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P70390-1", "uniprot_id": "SHOX2_MOUSE", "id": "P70390-1", "name": "Short stature homeobox protein 2", "aln": "MEELTAFVSKSFDQ--------------------KVKEKKEAITYREVLESGPLRG----AKEP-GCVEPGRDDRSSPAVRAAGGGGGAGGGGGGGGGGGGGAGGGGAGGGAGGGRSP----VRELDMG---------------AAERSREPGSPRLT---------EVSPELKDRKDDAKGMEDEGQTKIKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQLHKGVLIG-----AASQFEACRVAPYVNVGALR---MPFQQDSHCNVTPLSFQVQAQ------LQLDSAVAH-------AHHHLHPHLAAHAPYMMFPAPPFGLPLATLAADSASAAS----------VVAAAAAAKTTSKNSSIADLRLKAKKHAAALGL------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O35750-1", "uniprot_id": "SHOX2_RAT", "id": "O35750-1", "name": "Short stature homeobox protein 2", "aln": "---------------------------------------------------------------------------------------------------------------------------RELDMG---------------AAERSREPGSPRLT---------EVSPELKDRKEDAKGMEDEGQTKIKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQLHKGVLIG-----AASQFEACRVAPYVNVGALR---MPFQQDSHCNVTPLSFQVQAH------VQLDSAVRA-------AHHHLHPHLAAHGPYMMFPAPPFGLPLATLAADSASAAS----------VVAAAAAAKTTSKNSSIADLRLKAKKHAAALGL------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A8DYR8-1", "uniprot_id": "A8DYR8_DROME", "id": "A8DYR8-1", "name": "Homeobox protein unc-4", "aln": "MEQLAQFVTKSFEFNLTNNSVHALFNSMTGARLKKPTEVKNSIFINSISSGGSYADTCASGEESVDIDITDLSVSESNTILAIDPEPTEESHSQREEHVETYSLSPTLHKAAVEPKPKNWLISEDLDVDSQPEDPKMSGLPTASITECTEDSNTPKLAPDKPLLPEECVSPEPSRNREHCDPLDTS-LVNTKQRRSRTNFTLDQLNELERLFEETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKHENQMHKGFLVGSRSPPIATPLEPCRVAPYVSLAALRSSSVPSHPAAATSSNPQAPGVSGTSSSGKVVTVDSPHNHNPAISRSAIKQFSSTVAAAAAFSAFDPAIISVAAHQYAAAITNGTVPAGLFSVPQYSINLAAFAAAHSKSSSIADLRMKAKKHSESLGLQADMVL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:**:. :* :.:..:*:*: **** . .::... :: . .: ***********:*********:*************************************:***:***.*:* *: :*.*******.:.*** :* : : . .* : *.. : :**. * ::: . :** ..: * .. :.:. ** :..: : ** * : **.*******:*****: :*** ", "identical_positions": 117, "similar_positions": 72, "identity": "27.79%" }, { "cls_id": "homologset.agr.MGI:1201674", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P84025-1", "uniprot_id": "SMAD3_RAT", "id": "P84025-1", "name": "SMAD family member 3", "aln": "MSSILPFTPPIVKRLLGWKKG-EQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNVNTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIE-------PQ----------------SNIPETPPPG-------YLSEDGETSDHQMN-------HSMDAGSPNLSP-------------------NPMSPAHNN--------LDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BUN5-1", "uniprot_id": "SMAD3_MOUSE", "id": "Q8BUN5-1", "name": "SMAD family member 3", "aln": "MSSILPFTPPIVKRLLGWKKG-EQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNVNTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIE-------PQ----------------SNIPETPPPG-------YLSEDGETSDHQMN-------HSMDAGSPNLSP-------------------NPMSPAHNN--------LDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P84022-1", "uniprot_id": "SMAD3_HUMAN", "id": "P84022-1", "name": "SMAD family member 3", "aln": "MSSILPFTPPIVKRLLGWKKG-EQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNVNTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIE-------PQ----------------SNIPETPPPG-------YLSEDGETSDHQMN-------HSMDAGSPNLSP-------------------NPMSPAHNN--------LDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O96660-1", "uniprot_id": "SMAD2_DROME", "id": "O96660-1", "name": "SMAD family member 2", "aln": "---MLPFTPQVVKRLLALKKGNEDNSVEGKWSEKAVKNLVKKIKKNSQLEELERAISTQNCQTRCVTVPRSKPAPAGEHLRKGLPHVIYCRLWRWPDLQSQNELKPLDHCEYAFHLRKEEICINPYHYKKIELSILVPKSLPTPPDSIVDYP-LDNHTHQIPNNTDYNAAIIRSASLSPPQYMELGGAGPVSVSSSASSTPATAAGGGGGPSSSSSSSSSAASAYQQQQQQLSFGQNMDSQSSVLSVGSSIPNTGTPPPGYMSEDGDPIDPNDNMNMSRLTPPADAAPVMYHEPAFWCSISYYELNTRVGETFHASQPSITVDGFTDPSNSERFCLGLLSNVNRNEVVEQTRRHIGKGVRLYYIGGEVFAECLSDSSIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLSQSVSQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDRVLTQMGSPRLPCSSMS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :***** :*****. *** *:*. * **.*****.****:**..**:***:**:*** :*:*:*:*** . ******************:*::**:.:: **:**:::*:*:*:*****:::* .:* * :* .: .::* **:::*.**:**:: *.* ** *. * *.. * *... :* :* : :.**: *. ** :*:.* .* * ** * ************** ************:************************* .** ******:*******************:****************************************:***.***************************************************:******** : ***:*", "identical_positions": 297, "similar_positions": 77, "identity": "60.61%" }, { "cls_id": "homologset.agr.MGI:1201675", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63572-1", "uniprot_id": "TESK1_RAT", "id": "Q63572-1", "name": "Dual specificity testis-specific protein kinase 1", "aln": "----------------------------------------MAGERPPLRGPGPG--ETPVEGP---GGAGGGPGRGRP--------------SSYRALRSAVSSLARVDDFDCAEKIGAGFFSEVYKVRHRQSGQVMVLKMNKLPSNRSNTLREVQLMNRLRHPNILRFMGVCVHQGQLHALTEYMNGGTLEQLLS-SPEPLSWPVRLHLALDIAQGLRYLHAKGVFHRDLTSKNCLVR-REDGGFTAVVGDFGLAEKIPVYREGARKEPLAVVGSPYWMAPEVLRGELYDEKADVFAFGIVLCELIARVPADPDYLPRTEDFGLDVPAFRTLVGNDCPLPFLLLAIHCCSMEPSARAPFTEITQHLEQILEQLPEPTPLAKMPLAKAPLTYNQGSVPRGGPSATLPRSDP-----------------------------RLSRSRSDLFLPPSPESPPSWGDNLTRVNPFSLREDLRGGKIKLLDTPCKPATPLPLVPPSP-LTSTQLPLVASPESLVQPETPVRRCR-------SLPSSPELPRRMETALPGP--GPSPVGPSTEERMDCEGSS--------------PEPEPPGPAPQLP----------------------LAVATDN-----FISTCS-----SASQPWSARPGPSLNNNPPAVVVNSPQGWAREPWNRAQHSLPRAAALERTE--------------------------------PSPPPSAPREQEEGLPCPGCCLSPFSFGFLSMCPRPTP------AVARYRNLNC-----EAGSLLCHRGHHAKPPTPS-----LQLPGARS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70146-1", "uniprot_id": "TESK1_MOUSE", "id": "O70146-1", "name": "Dual specificity testis-specific protein kinase 1", "aln": "----------------------------------------MAGERPPLRGPGPG--EAPGEGP---GGAGGGPGRGRP--------------SSYRALRSAVSSLARVDDFDCAEKIGAGFFSEVYKVRHRQSGQVMVLKMNKLPSNRSNTLREVQLMNRLRHPNILRFMGVCVHQGQLHALTEYMNGGTLEQLLS-SPEPLSWPVRLHLALDIAQGLRYLHAKGVFHRDLTSKNCLVR-REDRGFTAVVGDFGLAEKIPVYREGTRKEPLAVVGSPYWMAPEVLRGELYDEKADVFAFGIVLCELIARVPADPDYLPRTEDFGLDVPAFRTLVGNDCPLPFLLLAIHCCSMEPSTRAPFTEITQHLEQILEQQPEATPLAKPPLTKAPLTYNQGSVPRGGPSATLPRPDP-----------------------------RLSRSRSDLFLPPSPESPPSWGDNLTRVNPFSLREDLRGGKIKLLDTPCKPATPLPLVPPSP-LTSTQLPLVTTPDILVQPETPVRRCR-------SLPSSPELPRRMETALPGP--GPSPMGP-TEERMDCEGSS--------------PEPEPPGLAPQLP----------------------LAVATDN-----FISTCS-----SASQPWSPRSGPPLNNNPPAVVVNSPQGWAREPWNRAQHSLPRAAALERTE--------------------------------PSPPPSAPREPEEGLPCPGCCLGPFSFGFLSMCPRPTP------AVARYRNLNC-----EAGSLLCHRGHHAKPPTPS-----LQLPGARS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15569-1", "uniprot_id": "TESK1_HUMAN", "id": "Q15569-1", "name": "Dual specificity testis-specific protein kinase 1", "aln": "----------------------------------------MAGERPPLRGPGPGPGEVPGEGPPGPGGTGGGPGRGRP--------------SSYRALRSAVSSLARVDDFHCAEKIGAGFFSEVYKVRHRQSGQVMVLKMNKLPSNRGNTLREVQLMNRLRHPNILRFMGVCVHQGQLHALTEYMNGGTLEQLLS-SPEPLSWPVRLHLALDIARGLRYLHSKGVFHRDLTSKNCLVR-REDRGFTAVVGDFGLAEKIPVYREGARKEPLAVVGSPYWMAPEVLRGELYDEKADVFAFGIVLCELIARVPADPDYLPRTEDFGLDVPAFRTLVGDDCPLPFLLLAIHCCNLEPSTRAPFTEITQHLEWILEQLPEP-----APLTRTALTHNQGSVARGGPSATLPRPDP-----------------------------RLSRSRSDLFLPPSPESPPNWGDNLTRVNPFSLREDLRGGKIKLLDTPSKP--VLPLVPPSP-FPSTQLPLVTTPETLVQPGTPARRCR-------SLPSSPELPRRMETALPGP--GPPAVGPSAEEKMECEGSS--------------PEPEPPGPAPQLP----------------------LAVATDN-----FISTCS-----SASQPWSPRSGPVLNNNPPAVVVNSPQGWAGEPWNRAQHSLPRAAALERTE--------------------------------PSPPPSAPREPDEGLPCPGCCLGPFSFGFLSMCPRPTP------AVARYRNLNC-----EAGSLLCHRGHHAKPPTPS-----LQLPGARS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FEW6-1", "uniprot_id": "E7FEW6_DANRE", "id": "E7FEW6-1", "name": "dual-specificity kinase", "aln": "-----------------------------------------MSIFMDQDDLDPEASDSLMHGV-------HGAHRPRP--------------SSYRALRSAVSSLARLDDFIC-EKIGSGFFSEVFKVQHRSTGQVMALKMNTMASNKANMLKEVQLMNRLRHPNILRFVGVCVHEGHLHALTEYINGGNLEQLLN-SDVLLSWSVRINLSLDIARGLQYLHSKGIFHRDLTSKNCLVR-WENGHCTAVVGDFGLAEKIPDHSEEAEKQSLAVVGSPYWMAPEVLRGERYNEKVDVFAYGIILCEIIGRIQADPDFLPRTEDFGLDVEAFRLMVE-DCPAHFFNLAVVCCGMSPDSRPCFSEVVAELEKRESDELQT----DHLESDVQDQMSTSSTPLSRAHSLDIASDP-----------------------------VLCRSKSAVLLPP---SPILNNTTPMRVNPFSQRQDLNGGRIKLFDTPSKSVISLTFTLPPPPDPSSPVPPR-----------SHRRTQ-------SLPCKPQD-IQSLYSTAEKRMNHQSIMDRDVNMLEIGGDS--------------VLTMSSGSIADLSGVLDPNTTGSNPEQEENLELRSQDVLADDSGLPLDLEVLSPNKWRSTEELMDCTSSPDTLDGAVDSTKQFSNGWS-SPVSNGPPSLPPLLDLDNNNSTIPINRPLGWG--------------VNNSNG-ATTPLTPTEQDEVVSCPGCCLAGMSF--PSICTRRAR-------QNPYKNLNG----DAAGKRLLCK---ALPPSPT--EPNITLPGTRT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9Q613-1", "uniprot_id": "A0A8M9Q613_DANRE", "id": "A0A8M9Q613-1", "name": "dual-specificity kinase", "aln": "---------------------------------------------MDQDE-NQEPCEPPLHAL-------YGPNRIRP--------------SSYRALRSAVSSLARIDDFFC-EKIGSGFFSEVFKVQHRITGQVMALKMNTLASNKANMLREVQLMNRLCHPNILRFLGVCVHEGQLHALTEYINGGNLEQLLD-SDIYLSWTVRIGLSLDIARGLQYLHSKGIFHRDLTSKNCLVR-CENGAFTAVVGDFGLAEKIPDYSDGVEKQPLAVVGSPYWMAPEMLRGELYNEKVDVFAYGIILCEIIARIEADPDILPRTEDFGLDVDTFEHMVG-DCPPSFLQMAVDCCNMNADSRPAFSEIVVMLERIERERVKS----EIPV--ILEPIAIDVSPYRRRSSPCHPCDQ-----------------------------RLSRSQSDMLPPAT--SPCLG--TPARVNPFSLRQDLNGGRIKLFDTPSKSVISLTFTLPPPPDPSASPPLSGSPG----LRGPPRRCR-------SLPCTPELGRQLPFRDQEVEEDRSEELGQETKDKELEGQQ--------------DAVEDSGLVLDLDMVSLERVE----EEEE-----DEEVEKEGQSLTEPMDCSS-----SPDTTEGNVSGKRLISGSSYSSSLQSNGWA-TPISNGPPLLPPLPRLDNNNGVLRPGRPFAWVR-------------LNGYRGPAPEPLPPTEQDDVISCPACCLAGFSF--PSLCLRGAPPSRRGPPRRPYRTFNGGDASTATAKGLLCRGATGLAPSTASCEPGLPLPEAQT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VE06-1", "uniprot_id": "Q9VE06_DROME", "id": "Q9VE06-1", "name": "dual-specificity kinase", "aln": "MSLNQHSGPGPPSEICGLSVDQVDSSAASPFIWPSTAGMCTTATTVTTSTNGDATAEAPVKHQPLHNGGWIGNGLPPAPVTRTISSDRLVTGSSCRALRTAVSALYSVDDFVK-EKIGSGFFSEVYKVTHRTTGQVMVLKMNQLRANRPNMLREVQLLNKLSHANILSFMGVCVQEGQLHALTEYINGGSLEQLLANKEVVLSATQKIRLALGIARGMSYVHDAGIFHRDLTSKNVLIRNLANDQYEAVVGDFGLAAKIPVK---SRKSRLETVGSPYWVSPECLKGQWYDQTSDVFSFGIIQCEIIARIEADPDMMPRTASFGLDYLAFVELCPMDTPPVFLRLAFYCCLYDAKSRPTFHDATKKLTLLLEKYEHESSAGASPLSSLELINCSPGGSDSENVTLTPRASVPTVATICTAPAGTLTPRHLQEVDEDGFRFPSKKSASAALPGTPNGSAGSSGFDDHILKSRVRRATQKLEAEILLHRRSLSENIIHFPMHTSPSDKARCHQMQRQRSSTHSPTPPRQLSSVQLPATSIPDPPPLPKPVPAVLTLRKVGDPQYKPTSEKDHNGSKPNPFEALAQLRGVKKILDANPKTYAAGVGDLFSSCFEMLAPFFKELAAMQSKAGAQGGGTSTEETSTGNKASAATPSEPKSLPVSPHMTRKYSAIELRLPQRISNAAPPAVTSAPPPSIALPTDEDDCDDCNSEGEDPDGGGNCADAESSSDDSAVRPSTVPTARKYRANSLYAHPLFRGSNGTSMKSTSTGEFESPTLLKASASTITLTASVGATNSCEDLTESARKSKEQASSGATAAVQALPTPMSGCSTRLVETPVSVSSCTDLELDELKNTCDLNELKNSCEQLPLKTNLTRRDSIESGFFSCFNEESDAAITNNSFGRQLNGIGSLGFGCGGGGNSSNCCYEKLKTQLMLDACVSADSEINDKLASLCRCCYYATSTSNAAVTAAAAAAQQQQQSHLLNDTSSTSSSVLLIDNDPAVIGGNTSSSTALDSMDDLDADIVASRRTHQRRYTCHHALLSGNGSESQMAATASLINRLALDSEIHTLLQRSPFATNQLLYCKNRTSSIYTDSSDDISSLAGSDSLLWDDRSFTALPSTRSAQIAKIVEYFERKRQDSSPPSVHHRNGNGTVAAAVAASALGSNYLSYESRRYSDFKRHLNADGLCFDLDKKPAQQRMMVCEGAVKSKLPIFDKKKQQQGG", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . * . ** ****:***:* :*** ****:******:** ** :****.**** : :*: * *:****:*:* *.*** *:****::*:*******:***.***** . ** . :: *:*.**:*: *:* *:********* *:* : ********* *** .*. * .******::** *:*: *::. ***::**: **:*.*: **** :*** .**** :* : * * *: :*. ** ...:*. * : . * . . . : . :* * : . *. ::. * . *:. . . : : .. .: . *: *:* * . : : . : . . . :.. . . .: : . * * : :. * . : : . . . * . .:. : . * . :.: : : ", "identical_positions": 160, "similar_positions": 130, "identity": "13.15%" }, { "cls_id": "homologset.agr.MGI:1201678", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O54898-1", "uniprot_id": "CAC1G_RAT", "id": "O54898-1", "name": "Voltage-dependent T-type calcium channel subunit alpha-1G", "aln": "------------------------------------------------------------------------------------MDEEEDGAGAE--------------------------------------ESGQPRSFTQLNDLSG-----------------------------------------------------------------------------AGGRQG-----------PGSTEKDPG----------SADSEAEGLPYPALAPVVFFYLSQDSRPRSWCLRTVCNPWFERVSMLVILLNCVTLGMFRPCEDIACDSQRCRILQAFDDFIFAFFAVEMVVKMVALGIFGKKCYLGDTWNRLDFFIVIAGMLEYSLDLQNVSFSAVRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNRCFLP--ENFSLPLSV-----------DLEPYYQTENEDESPFICSQPRENGMRSCRSVPTLRGEGGGGPPCSLDYETYNSSSNTTCVNWNQYYTNCSAGEHNPFKGAINFDNIGYAWIAIFQVITLEGWVDIMYFVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRESQLMREQRVRFLSNASTLAS---FSEPGSCYEELLKYLVYILRKAARRLAQVSRAIGVR-----AGLLS------------------------------------------------------------------SPVARSGQEPQ---------------------PSGSCTRSHRRLSVHHLVHHHHHHHHHYHLG-----------------------NGTLRVPRASPEIQDRDANGSRRLMLP-------------------------------PPS-----------------TPTPSGGPPRGAESVHSFYHADCHLEPVRCQAPPPRCPSEASG----------------RTVGSGKVYPTVHTSPP-----------------------------------PEILKDKALVEVAPSPGPPTLTSFNIPPGPFS-------SMHKLLETQSTGACHSS-----CKISSPCSKADSGACGPDSCPYCARTGAGEPESADHVMPDSDSEAVYEFTQDAQHSDLRDPHSRRRQR---------------------------SLGPDAEPS-----------SVLAFWRLICDTFR----KIVDSKYFGRGIMIAILVNTLSMGIEYHEQPEELTNALEISNIVFTSLFALEMLLKLLVYGPFGYIKNPYNIFDGVIVVISVWEIVG--------QQGGGLSVLRTFRLMRVLKLVRFLPALQRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHLFG---CKFASE--------------RDGDTLPDRKNFDSLLWAIVTVFQILTQEDWNKVLYNGMASTSSWAALYFIALMTFGNYVLFNLLVAILVEGFQAEG---------------------------DATKSESEPD----------------------------------------------------------FFSPSVDG----------------------DGDRKKRLALVALG------------------------------EHAELRKSLLPPLIIHTAATPMSHPKSSST----------------------------------------------------------------------GVGEALGSGS----------RRTSSSGSAEPGAAHHEMKCPPSARSSPHSP--WSAASS------------------WTSRRSSRNSLGRAPSLK--------RRSPSGERRS--------------LLSGEGQESQDEEE----------------------------SSEEDRASPAGSDHRHRGSLEREAKSS-----------FDLPDTLQVPGLHRTASGRSSASEHQDCNGKSASGRLA------RTLRTDDPQLDGDDDND-EGNLSKGE-RIQAWVRSR-----------------------------------------------------------------------------------------LPACCRERDSWSAYIFPPQSRFRLLCHRIITHKMFDHVVLVIIFLNCITIAMERPKIDPHSAERIFLTLSNYIFTAVFLAEMTVKVVALGWCFGEQAYLRSSWNVLDGLLVLISVIDILVSMVSDSGTKILGMLRVLRLLRTLRPLRVISRAQGLKLVVETLMSSLKPIGNIVVICCAFFIIFGILGVQLFKGKFFVCQGEDTRNITNKSDCAEAS-YRWVRHKYNFDNLGQALMSLFVLASKDGWVDIMYDGLDAVGVDQQPIMNHNPWMLLYFISFLLIVAFFVLNMFVGVVVENFHKCRQHQEEEEARRREEKRLRRLEKKRR-----------SKEKQMAEAQCKPYYSDYSRFRLLVHHLCTSHYLDLFITGVIGLNVVTMAMEHYQQPQILDEALKICNYIFTVIFVFESVFKLVAFGFRRFFQDRWNQLDLAIVLLSIMGITLEEIEVN--LSLPINPTIIRIMRVLRIARVLKLLKMAVGMRALLHTVMQALPQVGNLGLLFMLLFFIFAALGVELFGDLECDETHPCEGLGRHATFRNFGMAFLTLFRVSTGDNWNGIMKDTLRD-CDQESTCYN-----TVISPIYFVSFVLTAQFVLVNVVIAVLMKHLEESNKEAKEEAELEAELELEMKTLSPQPHSPLGSPFLWPGVEGVNSTDSPKPGAPHTTAHIGAAS-GFSLEHPT---------------------------------------------------------------------------------------------MVPHPEEVPVPLGPDLLTVRKSGVSRTHSLPNDSYMCRNGSTAERSLGHRGWGLPKAQSGSILSVHSQPADTSCILQLPKDVHYLLQPHGAPTWGAIPKLPPPGRSPLAQRPLRRQAAIRTDSLDVQGLGSREDLLSEVSGPSCPLTRSSSFWGGSSIQVQQRSGIQSKVSKHIRLPAPCPGLEPSWAKDPPETRSSLELDTELSWISGDLLPSS-QEEPLFPRDLKKCYSVETQSCRRRPGFWLDEQRRHSIAVSCLDSGSQPRLCPSPSSLGGQPLGGPGSRPKKKLSPPSISIDPPESQGSRPPCSPGVCLRRRAPASDSKDPSVSSPLDSTAASPSPKKDTLSLSGLSSDPTDMDP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5SUF7-1", "uniprot_id": "Q5SUF7_MOUSE", "id": "Q5SUF7-1", "name": "Voltage-dependent T-type calcium channel subunit alpha", "aln": "------------------------------------------------------------------------------------MDEEEDGAGAE--------------------------------------ESGQPRSFTQLNDLSG-----------------------------------------------------------------------------AGGRQG-----------PGSTEKDPG----------SADSEAEGLPYPALAPVVFFYLSQDSRPRSWCLRTVCNPWFERVSMLVILLNCVTLGMFRPCEDIACDSQRCRILQAFDDFIFAFFAVEMVVKMVALGIFGKKCYLGDTWNRLDFFIVIAGMLEYSLDLQNVSFSAVRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNRCFLP--ENFSLPLSV-----------DLEPYYQTENEDESPFICSQPRENGMRSCRSVPTLRGEGGGGPPCGLDYEAYNSSSNTTCVNWNQYYTNCSAGEHNPFKGAINFDNIGYAWIAIFQVITLEGWVDIMYFVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRESQLMREQRVRFLSNASTLAS---FSEPGSCYEELLKYLVYILRKAARRLAQVSRAVGVR-----AGLLS------------------------------------------------------------------SPVARGGQEPQ---------------------PSGSCSRSHRRLSVHHLVHHHHHHHHHYHLG-----------------------NGTLRVPRASPEIQDRDANGSRWLMLP-------------------------------PPS-----------------TPTPSGGPPRGAESVHSFYHADCHLEPVRCQAPPPRSPSEASG----------------RTVGSGKVYPTVHTSPP-----------------------------------PEMLKDKALVEVAPSPGPPTLTSFNIPPGPFS-------SMHKLLETQSTGACHSS-----CKISSPCSKADSGACGPDSCPYCARTGAGEPESADHEMPDSDSEAVYEFTQDAQHSDLRDPHRRRRP----------------------------SLGPDAEPS-----------SVLAFWRLICDTFR----KIVDSKYFGRGIMIAILVNTLSMGIEYHEQPEELTNALEISNIVFTSLFALEMLLKLLVYGPFGYIKNPYNIFDGVIVVISVWEIVG--------QQGGGLSVLRTFRLMRVLKLVRFLPALQRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHLFG---CKFASE--------------RDGDTLPDRKNFDSLLWAIVTVFQILTQEDWNKVLYNGMASTSSWAALYFIALMTFGNYVLFNLLVAILVEGFQAEEIGKRE----DTSGQLSCIQLPVNSQGGDATKSESEPD----------------------------------------------------------FFSPSVDG----------------------DGDRKKRLALVALG------------------------------EHSELRKSLLPPLIIHTAATPMSLPKSSST----------------------------------------------------------------------GVGEALGSGS----------RRTSSSGSAEPGTAHHEMKSPPSARSSPHSP--WSAASS------------------WTSRRSSRNSLGRAPSLK--------RRSPSGERRS--------------LLSGEGQESQDEEE----------------------------SSEEDRASPAGSDHRHRGSLEREAKSS-----------FDLPDTLQVPGLHRTASGRSSASEHQDCNGKSASGRLA------RTLRADDPPLDGDDGDD-EGNLSKGE-RLRAWVRAR-----------------------------------------------------------------------------------------LPACCRERDSWSAYIFPPQSRFRLLCHRIITHKMFDHVVLVIIFLNCITIAMERPKIDPHSAERIFLTLSNYIFTAVFLAEMTVKVVALGWCFGEQAYLRSSWNVLDGLLVLISVIDILVSMVSDSGTKILGMLRVLRLLRTLRPLRVISRAQGLKLVVETLMSSLKPIGNIVVICCAFFIIFGILGVQLFKGKFFVCQGEDTRNITNKSDCAEAS-YRWVRHKYNFDNLGQALMSLFVLASKDGWVDIMYDGLDAVGVDQQPIMNHNPWMLLYFISFLLIVAFFVLNMFVGVVVENFHKCRQHQEEEEARRREEKRLKRLEKKRRNLMLDDVIASGSSASAASEAQCKPYYSDYSRFRLLVHHLCTSHYLDLFITGVIGLNVVTMAMEHYQQPQILDEALKICNYIFTVIFVLESVFKLVAFGFRRFFQDRWNQLDLAIVLLSIMGITLEEIEVN--ASLPINPTIIRIMRVLRIARVLKLLKMAVGMRALLDTVMQALPQVGNLGLLFMLLFFIFAALGVELFGDLECDETHPCEGLGRHATFRNFGMAFLTLFRVSTGDNWNGIMKDTLRD-CDQESTCYN-----TVISPIYFVSFVLTAQFVLVNVVIAVLMKHLEESNKEAKEEAELEAELELEMKTLSPQPHSPLGSPFLWPGVEGVNSPDSPKPGAPHTTAHIGAASSGFSLEHPTDRQLFDTISLLIQGSLEGELKLMDELAGPGGQPSAFPSAPSPGDSDPQIPLAEMEALSLTSEIVSEPSCSLALTDDSLPDDTHTLLLSALESNMVPHTEEGPVPLGPDLLTVRKSGVSRTHSLPNDSYMCRNGSTAERSLGHRGWGLPKAQSGSILSVHSQPADTSCILQLPKDAHYLLQPHGAPTWGAIPKLPPPGRSPLAQRPLRRQAAIRTDSLDVQGLGSREDLLSEVSGPSCPLTRSSSFWGGSSIQVQQRSGSQSKVSKHIRLPAPCPGLEPSWAKDPQETRSSLELDTELSWISGDLLPSS-QEEPLSPRDLKKCYSVEAQSCRRRPGSWLDEQRRHSIAVSCLDSGSQPRLCPSPSSLGGQPLGGPGSRPKKKLSPPSISIDPPESQGPRPPCSPGVCLRRRAPASDSKDPSASSPLDSTAASPSPKKDALSLSGLSSDPTDLDP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43497-1", "uniprot_id": "CAC1G_HUMAN", "id": "O43497-1", "name": "Voltage-dependent T-type calcium channel subunit alpha-1G", "aln": "------------------------------------------------------------------------------------MDEEEDGAGAE--------------------------------------ESGQPRSFMRLNDLSG-----------------------------------------------------------------------------AGGRPG-----------PGSAEKDPG----------SADSEAEGLPYPALAPVVFFYLSQDSRPRSWCLRTVCNPWFERISMLVILLNCVTLGMFRPCEDIACDSQRCRILQAFDDFIFAFFAVEMVVKMVALGIFGKKCYLGDTWNRLDFFIVIAGMLEYSLDLQNVSFSAVRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNRCFLP--ENFSLPLSV-----------DLERYYQTENEDESPFICSQPRENGMRSCRSVPTLRGDGGGGPPCGLDYEAYNSSSNTTCVNWNQYYTNCSAGEHNPFKGAINFDNIGYAWIAIFQVITLEGWVDIMYFVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRESQLMREQRVRFLSNASTLAS---FSEPGSCYEELLKYLVYILRKAARRLAQVSRAAGVR-----VGLLS------------------------------------------------------------------SPAPLGGQETQ---------------------PSSSCSRSHRRLSVHHLVHHHHHHHHHYHLG-----------------------NGTLRAPRASPEIQDRDANGSRRLMLP-------------------------------PPS-----------------TPALSGAPPGGAESVHSFYHADCHLEPVRCQAPPPRSPSEASG----------------RTVGSGKVYPTVHTSPP-----------------------------------PETLKEKALVEVAASSGPPTLTSLNIPPGPYS-------SMHKLLETQSTGACQSS-----CKISSPCLKADSGACGPDSCPYCARAGAGEVELADREMPDSDSEAVYEFTQDAQHSDLRDPHSRRQR----------------------------SLGPDAEPS-----------SVLAFWRLICDTFR----KIVDSKYFGRGIMIAILVNTLSMGIEYHEQPEELTNALEISNIVFTSLFALEMLLKLLVYGPFGYIKNPYNIFDGVIVVISVWEIVG--------QQGGGLSVLRTFRLMRVLKLVRFLPALQRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHLFG---CKFASE--------------RDGDTLPDRKNFDSLLWAIVTVFQILTQEDWNKVLYNGMASTSSWAALYFIALMTFGNYVLFNLLVAILVEGFQAEEISKRE----DASGQLSCIQLPVDSQGGDANKSESEPD----------------------------------------------------------FFSPSLDG----------------------DGDRKKCLALVSLG------------------------------EHPELRKSLLPPLIIHTAATPMSLPKSTST----------------------------------------------------------------------GLGEALGPAS----------RRTSSSGSAEPG-AAHEMKSPPSARSSPHSP--WSAASS------------------WTSRRSSRNSLGRAPSLK--------RRSPSGERRS--------------LLSGEGQESQDEEE----------------------------SSEEERASPAGSDHRHRGSLEREAKSS-----------FDLPDTLQVPGLHRTASGRGSASEHQDCNGKSASGRLA------RALRPDDPPLDGDDADD-EGNLSKGE-RVRAWIRAR-----------------------------------------------------------------------------------------LPACCLERDSWSAYIFPPQSRFRLLCHRIITHKMFDHVVLVIIFLNCITIAMERPKIDPHSAERIFLTLSNYIFTAVFLAEMTVKVVALGWCFGEQAYLRSSWNVLDGLLVLISVIDILVSMVSDSGTKILGMLRVLRLLRTLRPLRVISRAQGLKLVVETLMSSLKPIGNIVVICCAFFIIFGILGVQLFKGKFFVCQGEDTRNITNKSDCAEAS-YRWVRHKYNFDNLGQALMSLFVLASKDGWVDIMYDGLDAVGVDQQPIMNHNPWMLLYFISFLLIVAFFVLNMFVGVVVENFHKCRQHQEEEEARRREEKRLRRLEKKRRNLMLDDVIASGSSASAASEAQCKPYYSDYSRFRLLVHHLCTSHYLDLFITGVIGLNVVTMAMEHYQQPQILDEALKICNYIFTVIFVLESVFKLVAFGFRRFFQDRWNQLDLAIVLLSIMGITLEEIEVN--ASLPINPTIIRIMRVLRIARVLKLLKMAVGMRALLDTVMQALPQVGNLGLLFMLLFFIFAALGVELFGDLECDETHPCEGLGRHATFRNFGMAFLTLFRVSTGDNWNGIMKDTLRD-CDQESTCYN-----TVISPIYFVSFVLTAQFVLVNVVIAVLMKHLEESNKEAKEEAELEAELELEMKTLSPQPHSPLGSPFLWPGVEGPDSPDSPKPGALHPAAHARSAS-HFSLEHPTDRQLFDTISLLIQGSLEWELKLMDELAGPGGQPSAFPSAPSLGGSDPQIPLAEMEALSLTSEIVSEPSCSLALTDDSLPDDMHTLLLSALESNMQPHPTELP---GPDLLTVRKSGVSRTHSLPNDSYMCRHGSTAEGPLGHRGWGLPKAQSGSVLSVHSQPADTSYILQLPKDAPHLLQPHSAPTWGTIPKLPPPGRSPLAQRPLRRQAAIRTDSLDVQGLGSREDLLAEVSGPSPPLARAYSFWGQSSTQAQQHSRSHSKISKHMTPPAPCPGPEPNWGKGPPETRSSLELDTELSWISGDLLPPGGQEEPPSPRDLKKCYSVEAQSCQRRPTSWLDEQRRHSIAVSCLDSGSQPHLGTDPSNLGGQPLGGPGSRPKKKLSPPSITIDPPESQGPRTPPSPGICLRRRAPSSDSKDPLASGPPDSMAASPSPKKDVLSLSGLSSDPADLDP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "M9PGH9-1", "uniprot_id": "M9PGH9_DROME", "id": "M9PGH9-1", "name": "", "aln": "MLPQPAAAVATATTTTTQSATSATSTAATSAAAAAARNGQRRRVAAATEGCNSNIGNSNSKLSSNTTTNTTKRVSQMHSNEEPPMTVIVDGGGGSNVSVSGGSSHRRGSQRLRKTSSSSANAKSASANPTERTSSGQRSSHRQTSNASDGGGSSRRRYQGKEHHDRRDRQDRQDRQDRQERSDRHERRDRRDEQQAARRRTGRRHSGASSLSDAAAATAAGRSRSRGGGRTGGAVSSSTGSSCNGSCSSDDGDSSHTSSSSSSSSSGEPNLPYPGFPEISIRALTQYTRPRNWCLMLITNPWFERVSILVILLNCITLGMYQPCVDDACVTNRCKILQIFDDIIFAFFALEMTIKMVAMGICGKNTYLADSWNRLDFFIVLAGLLEYVMHVENLNLTAIRTIRVLRPLRAINRIPSMRILVMLLLDTLPMLGNVLLLCFFVFFIFGIIGVQLWEGILRQRCSLMRTEGMVYPLTVPEVYRVRVRVNSLSQYYEFSKDQD--YICSTPNDSGMHLCGNFPPYR-IGSLVCNEEAKLFDFNEPTNTSCVNWNQYYTTCKQSGENPFQGTISFDNIGMAWVAIFLVISLEGWTDIMYYVQDAHSFWDWIYFVLLIVIGSFFMINLCLVVIATQFSETKKREMERMRQERARYTS-TSTLASSTNNSEPATCYAEIVKYIAHLWRRFKRRMLKKYRLYKYQRQQRKEGLLPNADNLTFSPSRIKCHHPKCPKYSNRKPSSIQDQMITVMVPLNSASNNINNNNNNNSNSSNHNGSGNHTAAGGGNNNNNNNNNNAASCTTVALVNGINGSAASVTMSSAHHQQHQLLQHQQQQHQNQQQQQQQQQHSSSDNTEQSLAPDGLPRSSSLKKSTAHHQLKPEGSAAEQKTILLKFPQQMIDSEQLILQLGNLGKSHPCTSGFLSPPTSASRRPSVMFNEYVLLHTPPALNADPATAGTTTTVAPTVATVAGTAAAAAAAAATGSGSGNNNHQNGGASGGAGTGGTTEKSNIFSTEKMTQAGDGSIWQVNLPQTIGTIANPYADCSELGIHDAMTCQELLAFSVAFSAALPTGQSTLESFYTSLARCDPHTAEALRAHHKPRSVPTGQNQTTPGAEGATVMVASTAGDTGQTLQPSTVSAVVGGTIDSHAANHRRKEHHQQSHHHHNNNNTTSHSRNYRSRQGQGNSRMREPRAPTGNYMEDYACCYDLYQNALSPLDERPRQRSPTTRCLISVYRCMSRVCSWIRRYIRRLVEHKYFQQGILLAILINTLSMGIEYHNQPPELTAIVETSNVVFSGIFAVEMLLKVVAEGPFRYIANGFNVFDGIIVILSAIEICQTFMGNGTGGGGSGLSVLRTFRLLRILKLVRFMPNLRRQLFVMLRTMDNVAVFFSLLVLFIFIFSILGMYLFGGKFCKFLDESGLERECTCPEIISRHPQCECDRKHFNNILWATVTVFQILTQEDWNVVLFNGMEKTSHWAALYFVALMTFGNYVLFNLLVAILVEGFSSERNERREREQRELVKKLREETLAENYSDGMYDESRSEADSSTTNDSYYEVRNRWRSAEDVRKLQDSVELIIEAKSNMHRQRLLQPTHDYQINELPASSAAPSASGTSGASAPGDRERDRDRDRDRERDRDRDRERDREAGGGGKEEGAQHAKPRGGLKKTYSIKERRSEAPRLSKIRLARDPPIITTTAATPQDSPSTTLEPGMSFRQWGDMEPPSPPSPSLLRPPNIFTGGQRSLDEGIPSIDLIPPSPVLSHKPLNILNASQLGVGMGGGVPSTAGSSSSMHSVIIDDISKSSSSTAAATPIYVPTISSTADAQSQSHSLNDVSVGSSPGGEIPATGMSRNANTGASTSGSSSSERLPLAPPPQQGSFKQRLRRGSSKKRRASALALATDDNPARRTLDNQARRTQDEEEEQQQLNNGGDNSCLLRNSNAVVSGSSSGTKETNRLSPQNSIRRLSNTLSIGSGPVGSRRASACIFNSQVYQNLNQPPKLRPGSGQRRMSSIELAFSKTSHLNLHNLEANRKSLSYTNSKMDLDKWNKSYGNLNEPDNMLQQYMEARDKRKNSISHYNLKKRLEEKELQQLQQLHQQQLLQQRQDSFSSTTQQQQQQLQQHRLSKDQQQLAMQPHSMVPGGGERYSKLKMLIEQLTPKHFTTEREDYSLYIFPEDNRFRQICTWFVNQKWFDNVVLLFIALNCITLAMERPNIPPSSTERLFLATANYVFTVVFTVEMFIKVVATGMFYGHDAYFTSGWNIMDGSLVTISIIDLLMSLISESSPRIFGILRVFRLLRSLRPLRVINRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGTFYYCEGENIKGVRNADECRRIPGNVWTNRKYNFDDLGKALMSLFVLSSRDGWVNIMYTGLDAVGVDQQPIVNYNEWRLLYFIAFILLVGFFVLNMFVGVVVENFHRCREEQEKEEKIRRAAKRALQMEKKRR------------------RMHEPPYYTNYSPTRMFVHNVVTSKYFDLAIAAVIGLNVVTMAMEYYKMPSGLKYALKIFNYFFTAVFILEANMKLVALGWKLYLKDRWNQLDVGIVLLSIVGIVLEELETNTHQIIPINPTIIRVMRVLRIARVLKLLKMANGIRALLDTVMQALPQVGNLGLLFFLLFFIFAALGVELFGRLECSDEIPCQGLGEHAHFANFGMAFLTLFRVATGDNWNGIMKDTLRDNCDDAADCVRNCCVSSVIAPIFFVIFVLMAQFVLVNVVVAVLMKHLEESHKQMEDELDMEVELERELVREQEFAQEQKLCQQLAEAQSKAAAPPRPLAKVKSLPKNFIYSTPSLDKKFPAVSGVNNPS---LTSSAATNLNQVATAGSGGAAPGAVPAGSGAGPRRQTVQYFQQPPQSMLGG----------------------LSLAEMGGTLTPQALGARLGEPFGGGGGNKSGPRRQSYWQINPIRKRGVLSKERSLDEQAIRR-RNLEAKRTSCDSLPWGGDALDCRRGTIFESLESDGGGVGGGGSGGGGGGLGGGVSYDLRSVRSADVGHSEMDGDVSLSVVSALVPSVTTPLP--------PPLSLPIVTPTSTPTPLQLPMPMPMPMAHP-----PPRRPFGWSQSVDQGCLRSNLLLSVPRSMPPRSR----SGSTKQLFKQQALDEDADMDENSLLLPTAAGGGSGP---GSVAVIASSSLDLPDQSGSSKQILPDIALGVSKSDSS--DILRIISERRRMDQREQREPEQDQDNEAEDRDSDYKELLLVKSPQSS----MD-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * **.*.. .*** *. : .: *. .*** * ** ..* * *:.* .****.:. : : *:* :***.*** : ******:*:*******:****::** * ** ::**:*** ***:******:**.:****:** **: **.*:*********:**:*** :.::*:.::*:**:***********:******* *************************:***** *:**:** * *.: **:* .*. **: .:::: :*** *.:.**: * ..*. * *. . :*..:**:*********.*. . .***:*:*.***** **:*** **:****.****:* *****:::***:***::*********************:** : **::*.*: * :***** ***.:** *::**:.:: *: **: : * : ***. ... .*:: : .:.* : * : . *:*::*::::*:: : ..:*: . * ::: ..: ..: :* **: **. .. * * :. :. : . : . . *... .....** *. ..:::.* : : . * * .. ...* ..* .** *: . . . *: .: .** ::: ..: .. .*:* * .. *: : . *:: : ..:: :...:: *. *: : *: :*.* * . ** :*. :* ::*: *** :**::***:**********:** *** :* **:**:.:**:*****::. *** ** * :*:***:**::*. ** *.**********:*:******:* *:***.*:::******.* **:***********:*** *** .* *. : ***:*:.:*** ************* **:*** .** ******:**********************.:* :*.**.* :** .* * **.: : * . .::* : **:* ***** . *.:: *: .: *..* ::*** :* . :.....*:*..** *..** ** ** : * **. : **..* :**: *..:.:.:***** :.* :* ** .* :* .:*. : . :: :.*: * *..**: *. : . .*:: .* ::* :. :* *. :. ***.: : :: ::.:* **:.:* **** :.*** :* ::.:* **:***::* *****:*****:* * *:**:**: :**:**.** .** :**** * :*.:**: *.**::** ** **:**:*:*::*:*..:*:*:***:****:*******.** ******:**:***:******:***:***************.*: *:**: :.: * .:* . . *..:*****:**:********:*:****:*** ************:*:* * *****:*:*:*.****************:**:.**:** ** ** ::***** . : ***::** *::**:: **:*:** *:.************:*: *. *. **** **:**.:*::*: :****:*:: :::*******:.******:**.***:*.* :********:**************** *:****.****************:*************** ***.: **:***.** * ************:*************** **: : * . :**:**:** *** *********:**********:*: ::* ::*.*** *: . .:. . * . . :. * . . . : :: :. :.*: : *:. . .*** * :. * : * .*..:. : ... * .* * . . : *:.... . * . * . .. ** : .. :::* * . : : *.. : **. .. . : : . :: * * * .* * . . . ..: . : .:** . :. * .* . *.: :: * :.. : :. ..** * . : :....*. *.. ..* *.*::. .:*:.. :. *** :.::* . :: ... *: * * ** :* ", "identical_positions": 1005, "similar_positions": 658, "identity": "30.52%" }, { "cls_id": "homologset.agr.MGI:1201679", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9R066-1", "uniprot_id": "CXAR_RAT", "id": "Q9R066-1", "name": "Coxsackievirus and adenovirus receptor homolog", "aln": "---MALLLCFVLLCGVADFTSSLSITTP-EQRIEKAKGETAYLPCKFTLEPEDQGPLDIEWLISPSDNQKVDQVIILYSGDKIYDNYYPDLKGRVHFTSNDVKSGDASINVTNLQLSDIGTYQCKVKKAPGVANRKFLLTVLVKPSGTRCFVDGSGEIGNDFKLKCEPKEGSLPLQYEWQKLSDSQKMPTPWLAEMTSPVISVKNASSEYSGTYSCTVQNRVGSDQCMLRLDVVPPSNRAGTIAGAVIGTLLALVLIGAILFCCHKKRREEKYEKEVHHDIREDVPPPKSRTSTARSY--IGSNHSSLGSMSPSNMEGYSKTQYNQVPSEDFERAP-QSPTLAPAKVAAPNLSRMGAVPVMIPAQSKDGSIV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97792-1", "uniprot_id": "CXAR_MOUSE", "id": "P97792-1", "name": "Coxsackievirus and adenovirus receptor homolog", "aln": "---MARLLCFVLLCGIADFTSGLSITTP-EQRIEKAKGETAYLPCKFTLSPEDQGPLDIEWLISPSDNQIVDQVIILYSGDKIYDNYYPDLKGRVHFTSNDVKSGDASINVTNLQLSDIGTYQCKVKKAPGVANKKFLLTVLVKPSGTRCFVDGSEEIGNDFKLKCEPKEGSLPLQFEWQKLSDSQTMPTPWLAEMTSPVISVKNASSEYSGTYSCTVQNRVGSDQCMLRLDVVPPSNRAGTIAGAVIGTLLALVLIGAILFCCHRKRREEKYEKEVHHDIREDVPPPKSRTSTARSY--IGSNHSSLGSMSPSNMEGYSKTQYNQVPSEDFERAP-QSPTLAPAKVAAPNLSRMGAVPVMIPAQSKDGSIV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P78310-1", "uniprot_id": "CXAR_HUMAN", "id": "P78310-1", "name": "Coxsackievirus and adenovirus receptor", "aln": "---MALLLCFVLLCGVVDFARSLSITTP-EEMIEKAKGETAYLPCKFTLSPEDQGPLDIEWLISPADNQKVDQVIILYSGDKIYDDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKPSGARCYVDGSEEIGSDFKIKCEPKEGSLPLQYEWQKLSDSQKMPTSWLAEMTSSVISVKNASSEYSGTYSCTVRNRVGSDQCLLRLNVVPPSNKAGLIAGAIIGTLLALALIGLIIFCCRKKRREEKYEKEVHHDIREDVPPPKSRTSTARSY--IGSNHSSLGSMSPSNMEGYSKTQYNQVPSEDFERTP-QSPTLPPAKVAAPNLSRMGAIPVMIPAQSKDGSIV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q90Y50-1", "uniprot_id": "CXAR_DANRE", "id": "Q90Y50-1", "name": "Coxsackievirus and adenovirus receptor homolog", "aln": "MDMRTSFLCVTYVILLTGSACGLQITSTGQTSIEKASGESVKLDCQFTLASDDSGPLDIEWSLQPSDNQKEEKVVIVYSGDRAFEHYYDPLKGRVHFNSPDPKNGDASMNIMGLKATDTGTYQCKIKKVPGIASRKYLLTVMVRPSKPKCSAEGQTYVGKNMVLKCSSVEGTQPMEYIWERTSGNKLLPPLAILDKVTGTMTLKNATGDASGTYRCQAKNRVGTEECVVEVTITQPPNTAGIIAGVIICILLLLILLALILFCCCRARHKKKYEKEIAYEIREDVPPPKSRVSTARSFTSVGSQRSSLGSMSPSNLHEYSKPQYDKIPSEEYDRPPSHAPIPPPSRMAGPNLSRMGAIPVMIPAQNKDGSIV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :**.. : :.. : .*.**:. : ****.**:. * *:*** .:*.******* :.*:*** ::*:*:****: ::.** *******.* * *.****:*: .*: :* ******:**.**:*.:* *.*:*:** .:* .:*. :*.:: :**.. **: *::: *:: *..: :*. : : .: .:::***:.: **** * .:****:::*::.: :. *.* ** ***.:* ** * *:. *:*** : *:::*****: ::***********.*****: :**::**********:. ***.**:::***:::*.* ::* .*:::*.********:*******.******", "identical_positions": 178, "similar_positions": 129, "identity": "47.85%" }, { "cls_id": "homologset.agr.MGI:1201681", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V7Q0-1", "uniprot_id": "DEN5A_RAT", "id": "G3V7Q0-1", "name": "DENN domain-containing protein 5A", "aln": "----------------MSGGGGGGGSAPS----RFADYFVICGLDTETGLEPDELSALCQYIQASKARDG-------------ASPFISSTTEGENFEQTPLRRTFKSKVLARYPENVDWNPFDQDAVGMLCMPKGLAFKTQADPREPQFHAFIITREDGSRTFGFALTFYEEVTSKQICSAMQTLYHMHNAE-YDVLHAPLADGGDQSGMEDGEGIPG------TKLQRFNSYDISRDTLYVSKCICLITPMSFMKACRSVLQQLHQAVTSPQPPPLPLESYIYNVLYEVPLPPPGRSLKFSG----VYGP---IICQRPSTN-ELPLFDFPVKEVFELLGVENVFQLFTCALLEFQILLYSQHYQRLMTVAETITALMFPFQWQHVYVPILPASLLHFLDAPVPYLMGLHSNGLDDRSKLELPQEANLCFVDVDNHFIELPEDLPQFPNKLEFVQEVSEILMAFGVPPEGNLHCSESASKLKRIRASELVSDKKNGN-----------------------------------IAGSP---LHSYELLKEN----ETIARLQALVKRTG-------------VSLEK-----------LEVREDPSSNKDFKVQCDEEELRIYQLNIQ--IREVFANRFTQMFADYEVFVIQPSQDKESWLSNREQMQNFDKASFLSDQPEPYLPFLSRFLETQMFASFIDNKIMCHDDDDKDPVLRVFDSRVDKIRLLNVRTPTLRTSMYQKCTTVDEAEKAIELRLAKIDHTAVHPHLLDMKIGQGKYEPGFFPKLQSDVLCTGPASNKWTKRNAPAQWRRKDRQKQHTEHLRLDNDQRE-----------------------------------KYIQEARNMGSTIRQPKLSNLSPSVIAQTNWKFVEGLLKECRNKTKRMLVEKMGREAVELGHGEVNITGVEENTLIASLCDLLERIWSHGLQVKQGKSALWSHLLHYQENRQ-RKLTSGS-------------------LSTSGILLDSERRKSDASAVMS---------------------------PLRVSLIQDMRHIQNIGEIKTDVGKARAWVRLSMEKKLLSRHLKQLLSDHELTKKLYKRYAFLRCDDEKEQFLYHLLSFNAVDYFCFTNVFTTILIPYHILIVPSKKLGGSMFTANPWICISGELGETQILQIPRNVLEMTFECQNLGKLTTVQIGHDNSGLYAKWLVEYVMVRNEITGHTYKFPCGRWLGKGMDDGSLERVLVGELLTSLPEVDERP----CRTPPLQQSPSVIRRLVTISPNNKPKLNTGQIQESIGEAVNGIVKHFHKPEKER--GSLTLLLCGECGLVSALEQAFQHGFKSPRLF-KNVFIWDFLEKAQTYYET-----LEQNDVVPEENWHTRARN----------------FCRFVTAVNNTPRNIGKDGKFQMLVCLGARDHLLHHWIALLADCPITAHMYEDVALIKDHTLVNSLIRVLQTLQEFNITLDTSLVKGIDI----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PAL8-1", "uniprot_id": "DEN5A_MOUSE", "id": "Q6PAL8-1", "name": "DENN domain-containing protein 5A", "aln": "----------------MSGGGGGGGSAPS----RFADYFVICGLDTETGLEPDELSALCQYIQASKARDG-------------ASPFISSTTEGENFEQTPLRRTFKSKVLARYPENVDWNPFDQDAVGMLCMPKGLAFKTQADPREPQFHAFIITREDGSRTFGFALTFYEEVTSKQICSAMQTLYHMHNAE-YDVLHAPLADGGDQSGMEDGEGIPG------TKLQRFNSYDISRDTLYVSKCICLITPMSFMKACRSVLQQLHQAVTSPQPPPLPLESYIYNVLYEVPLPPPGRSLKFSG----VYGP---IICQRPSTN-ELPLFDFPVKEVFELLGVENVFQLFTCALLEFQILLYSQHYQRLMTVAETITALMFPFQWQHVYVPILPASLLHFLDAPVPYLMGLHSNGLDDRSKLELPQEANLCFVDVDNHFIELPEDLPQFPNKLEFVQEVSEILMAFGVPPEGNLHCSESASKLKRIRASELVSDKRNGN-----------------------------------IAGSP---LHSYELLKEN----ETIARLQALVKRTG-------------VSLEK-----------LEVREDPSSNKDFKVQCDEEELRIYQLNIQ--IREVFANRFTQMFADYEVFVIQPSQDKESWFTNREQMQNFDKASFLSDQPEPYLPFLSRFLETQMFASFIDNKIMCHDDDDKDPVLRVFDSRVDKIRLLNVRTPTLRTSMYQKCTTVDEAEKAIELRLAKIDHTAVHPHLLDMKIGQGKYEPGFFPKLQSDVLCTGPASNKWTKRNAPAQWRRKDRQKQHTEHLRLDNDQRE-----------------------------------KYIQEARNMGSTIRQPKLSNLSPSVIAQTNWKFVEGLLKECRNKTKRMLVEKMGREAVELGHGEVNITGVEENTLIASLCDLLERIWSHGLQVKQGKSALWSHLLHYQENRQ-RKLTSGS-------------------LSTSGILLDSERRKSDASAVMS---------------------------PLRISLIQDMRHIQNIGEIKTDVGKARAWVRLSMEKKLLSRHLKQLLSDHELTKKLYKRYAFLRCDDEKEQFLYHLLSFNAVDYFCFTNVFTTILIPYHILIVPSKKLGGSMFTANPWICISGELGETQILQIPRNVLEMTFECQNLGKLTTVQIGHDNSGLYAKWLVECVMVRNEVTGHTYKFPCGRWLGKGMDDGSLERVLVGELLTSLPEVDERP----CRTPPLQQSPSVIRRLVTISPNNKPKLNTGQIQESIGEAVNGIVKHFHKPEKER--GSLTLLLCGECGLVSALEQAFQHGFKSPRLF-KNVFIWDFLEKAQTYYET-----LEQNDVVPEENWHTRARN----------------FCRFVTAVNNTPRNIGKDGKFQMLVCLGARDHLLHHWIALLADCPITAHMYEDVALIKDHTLVNSLIRVLQTLQEFNITLDTSLVKGIDI----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6IQ26-1", "uniprot_id": "DEN5A_HUMAN", "id": "Q6IQ26-1", "name": "DENN domain-containing protein 5A", "aln": "----------------MSGGGGGGGSAPS----RFADYFVICGLDTETGLEPDELSALCQYIQASKARDG-------------ASPFISSTTEGENFEQTPLRRTFKSKVLARYPENVEWNPFDQDAVGMLCMPKGLAFKTQADPREPQFHAFIITREDGSRTFGFALTFYEEVTSKQICSAMQTLYHMHNAE-YDVLHAPPADDRDQSSMEDGEDTPV------TKLQRFNSYDISRDTLYVSKCICLITPMSFMKACRSVLEQLHQAVTSPQPPPLPLESYIYNVLYEVPLPPPGRSLKFSG----VYGP---IICQRPSTN-ELPLFDFPVKEVFELLGVENVFQLFTCALLEFQILLYSQHYQRLMTVAETITALMFPFQWQHVYVPILPASLLHFLDAPVPYLMGLHSNGLDDRSKLELPQEANLCFVDIDNHFIELPEDLPQFPNKLEFVQEVSEILMAFGIPPEGNLHCSESASKLKRLRASELVSDKRNGN-----------------------------------IAGSP---LHSYELLKEN----ETIARLQALVKRTG-------------VSLEK-----------LEVREDPSSNKDLKVQCDEEELRIYQLNIQ--IREVFANRFTQMFADYEVFVIQPSQDKESWFTNREQMQNFDKASFLSDQPEPYLPFLSRFLETQMFASFIDNKIMCHDDDDKDPVLRVFDSRVDKIRLLNVRTPTLRTSMYQKCTTVDEAEKAIELRLAKIDHTAIHPHLLDMKIGQGKYEPGFFPKLQSDVLSTGPASNKWTKRNAPAQWRRKDRQKQHTEHLRLDNDQRE-----------------------------------KYIQEARTMGSTIRQPKLSNLSPSVIAQTNWKFVEGLLKECRNKTKRMLVEKMGREAVELGHGEVNITGVEENTLIASLCDLLERIWSHGLQVKQGKSALWSHLLHYQDNRQ-RKLTSGS-------------------LSTSGILLDSERRKSDASSLMP---------------------------PLRISLIQDMRHIQNIGEIKTDVGKARAWVRLSMEKKLLSRHLKQLLSDHELTKKLYKRYAFLRCDDEKEQFLYHLLSFNAVDYFCFTNVFTTILIPYHILIVPSKKLGGSMFTANPWICISGELGETQIMQIPRNVLEMTFECQNLGKLTTVQIGHDNSGLYAKWLVEYVMVRNEITGHTYKFPCGRWLGKGMDDGSLERILVGELLTSQPEVDERP----CRTPPLQQSPSVIRRLVTISPNNKPKLNTGQIQESIGEAVNGIVKHFHKPEKER--GSLTLLLCGECGLVSALEQAFQHGFKSPRLF-KNVFIWDFLEKAQTYYET-----LEKNEVVPEENWHTRARN----------------FCRFVTAINNTPRNIGKDGKFQMLVCLGARDHLLHHWIALLADCPITAHMYEDVALIKDHTLVNSLIRVLQTLQEFNITLETSLVKGIDI----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B1L1-1", "uniprot_id": "A0A8M3B1L1_DANRE", "id": "A0A8M3B1L1-1", "name": "", "aln": "----------------MSTG---FSSSSC----RFADYFVICGLDTESGLEPDELSALCQYIQATKFTDG-------------ARGKLASANEGENFEQSPLRRTFKSKVLAHYPDNVEWNPFDQDAVGMLCMPKGLSFRTQTDTREPQFHSFIITREDGSRTYGFALTFFEEVTSKQICSAMQTLYHMHNAEQYDILHTPPTPRSPEDPRPTTQQLHASPAL--SRLQRFNSYDISRDTLYVSKCICLITPMAFAHACRKVLEQLHQAVTSPQPPPLPLESYVYNVLYEVPLPPAGRSLKFSG----VYRP---VICQRPSTA-ELPLFDFPLQEVFELLGLENILQLFTCALLEIQILLYSQHYQRLMTVAESITALMFPFQWQHVYVPILPASLLHFLDAPVPYLMGLHSNGQDDRTKLELPQEANLCFVDIDNHFIELPEDLPQFPNKLEFIQEISEVLLAFGLSPEANPQCSEGQSKIRGFRCGDMASDKRNGN-----------------------------------LAGSP---LNSF-LLREN----QTIARLQALVKRTG-------------VSLEK-----------LDVKDDASTNKDTKVQCEEEEMKMHQLNIR--VREVFANRFSQMFSDYEVFVIQPSQDKESWFSNRDQMQNFDKASFLSDQPEPYLPFLSRFLETQMFASFIDSKILCHDDEDKEHTLRVFDSRVDKIRMINVRTPTLRTSMYQKCTNIDEAEKAIEVRLCKIDHTALHPHLLDMKIGQGRYEPGFFPRLQSDVLSTGPTSNKWAKRSAPAQWRRKDRQKQHAEHLYLDNDQREHVECLFSELQLLLALDYYWFSQSFRPCLKSVKVDVKYIQEARNLGTTLRQPKLSNLSPSVIAQTNWKFVEGLLKECRNKTKRMLVEKMGREAVELGHGEVSITGVEENTLIASLCDLLERIWSHGLQVKQGKSALWSHLLHYQESKEKRDATPAG-------------------LGPPGIIHDTERRKSDASCAMP---------------------------PLKVSLIQDMRHIQNISEIKTDVGKARAWVRLSMEKKLLSRHLKQLLSDHELTKKLYKRYAFLRCDDEKEQFLYHLLSFNAVDYFCFTNVFTTIMIPYHVVIIPSKKLGGSMFTANPWVCVSGELAETGVLQVPKNTLEITFECQNLGKLTTVQMGHDNSGLYAKWLVECVMVRNGITGHTYKFPCGRWLGKGVDDGSLERILVGELVTN-MESDERM----CRTPPMQQSPGMMRRFVTISPNSKPKLNTGQIQESVGEAINGIVKHFHKPEKER--GSLTLLLCGEYGLVWALEQVFQHGFKSPRLF-KNVFIWDFLEKAQVYFES-----AERSQMTQDENWQMRVRH----------------FCHFMRAINSTPRNIGKDGKFQMLVCLGARDHLLHHWIALLAECPITAQMYEDVALLKDHSLVNSLIRVLQTLQEFNITLEASLVKGIGI----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W0E1-1", "uniprot_id": "Q9W0E1_DROME", "id": "Q9W0E1-1", "name": "", "aln": "MTTRENVVSSRLSKLMLSSGSGNGSGNGSGPNIQVAPSSTLVQSPTSPGEQSQSQSELNQLKRDADPQFSRFADYFVICGLDLDTGLEPDRFAGDNLHCSPLDRAYKSKPLAHYPENVPWNPFDAHGICMLSLPQGLRFRTQKHCIEPRFHSFATTREDGKRCYGFSLVFYEEIRNRNICGAIHTLQSMFITELSNGQQTHSLSRVKQDGPVSRSLPRHFKVAGQAPQSAQSYYDINKDKLYVAKSITLICQAPYAFAAQMFLKNLYRCLPRQPGAGISLESYVYNILYEVMLPQPGKSIRVYLPPTEPHLPPIALILQRPLLATELPLLDFPLRLLFKYLGVECVIQLLTCVLLENQVLLRSTDYQRLMIVGECITSLLFPFVWPHVYAPILPAALHHFLDAPVPFVMGLHAECEAAH---KIGSEATLCFVDIDKKHIQLPEELPVFPHKVDFMAEIGSVLDKFEIERDRDQEPSFRNGYVGRGAGGGVSGSGSSGSGGVDAMISSCTLPTGLQAARRSKERFQQMQETVYTLSGSPGGGVVDYQPLIAHPSRIDHVPRIADFLRRKGGIRGAGSPVGSPTVSLSSSPVGIYHDVDAVDATMPVSTRRAEKQKLSPVDQYYQDLRINNSVREIFLNRFVHMFHAYEYFVIYPNQARDEWISNRETLQNFDKSSFLSDQPEHHRAFLSRFLESQMFATLIDNKILAMWESQPDEQLQLFDQRVKLLRRRHGEN-MIAATSYEPCVLSQDSQQGFEKRLNCIDIEVTPP--SEILANRAAYFR-SFPLLEKGVLNQECASRGNSLR------RVKNGNKWRAREISLDQKPGS--------------------------------------NAINRLSANLTT---ADVSPALIAQANWTFVERLLKDIKSKTKRMLLEKMGNEAVALG---LKGDGIEENTLIASMCDLLEKIWSHGLQNKQGKSALWAHLQAYLEMQEARGAGDSSGTEQTPPVSSSPGGKMTIATASPALAWNAMRKRMDYLSTFQTDFDSPPSPNRSRSRDRNKFVGLEQLCPLPESLEFDVKNVLAMADIKTHIGYTRAWVRLSLEKKLLSRHFRTLLSDEALLRSLYKRSAFLRCEEEKEQFLYHLLTLNTVDYFSFTNIYPTTKLPYRVVIFPSRKYGSYHTSSNVWIMVSGTMNETQRVPVPKGSLEFIFHYKNLGLLTTMRIGHDNSGPSHKWLVEQVVMRNEVTGHTYKFPCGRWLGRGVDDDSTERLLVGQRVLTNAKNAELVPGSDTRTPPRTRSPSVQR---------QETLAPSEIQHQLGNCVNVLVKWHYKPSRDRDVGTLTNLLCGDDGLVKCLEQVFLCGFRSARFFGRNLYIWDYFTKIKELFEHNLQMELEDSSSSLDSSFSNGSGSGGNSLQRREISSIWRLYVQLMDEINGT--ALGKDGKFQLLICLSLREHLLTRLIKPMALTKVTHEMYEEESFLRRRNLLTFLIQILEPLDDCHIVLENSITQGIRIASQC", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* * .. . :.* .: *..* :.:. * * * : :. . .. *:*:. :** *::*** **:**:** ***** ..: **.:*:** *:** . **:**:* *****.* :**:*.*:**: .::**.*::** *. :* : :: :. . : . . ***.:*.***:*.* ** .: *.: .*::*::.:. . :.****:**:**** ** .*:*::. : * :* *** ****:***:: :*: **:* ::**:**.*** *:** * .***** *.* **:*:*** * ***.*****:* ********::****:: : :: .**.*****:*::.*:***:** **:*::*: *:..:* * : : : . * . : . : .. .*. ::*** : .: * : : :.*: :::*.* ***.. ::. *:.: * : . : :*.*. :**:* *** :** ** *** *.* ::.*::**: :*****:******** : .*******:****::**.**:. :.: : *::**.**. :* : .. : :: *: *. :::::.:* ** ** . * :: .:. * ** *:..** :*. : * * *: :* ::..: **:. . : . :.:.: :::**::***:**.*** ***: :.******:****.*** ** :. *:********:*****:******* ********:** * : :: * .. ....: :: *:: * . : ** ** *:::: :.:***.:* :*******:********:: ****. * :.**** *****::**********::*:****.***::.* :**:::*.**:* *. ::* *: :** : ** : :*:. **: *. :*** ***:::****** ***** *::** :**************:*:**.* **:***: : . : * **** :**.: * : .* ..:**..:*:.:* :** .:**.::* *:** ****: *** .***.* **:*.*:* :*::***:: * : :* * .. :..: : ::: :*.* :*******:*:**. *:*** : * :* :* .***: :::: :.*:. **::*:.*:: :*.*: *:.:** * ", "identical_positions": 516, "similar_positions": 411, "identity": "34.01%" }, { "cls_id": "homologset.agr.MGI:1201682", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97329-1", "uniprot_id": "KI20A_MOUSE", "id": "P97329-1", "name": "Kinesin-like protein KIF20A", "aln": "MSHRILSPPAGLLSDEDVVDSPILESTAADLRSVVRKD----LLSDCS-VISASLE--------------DKQ-ALLEDTSEKVKVYLRIRPFLTSELDRQEDQGCVCIENTETLVLQAPKDSFALKSNERGVGQATHKFTFSQIFGPEVGQVAFFNLTMKEMVKDVLKGQNWLIYTYGVTNSGKTYTIQGTSKDAGILPQSLALIFNSLQGQLHPTPDLKPLLSNEVIWLDSKQIRQEEMKKLSLLIGGLQEEELSTSVKKRVHTESRIGASNSFDSGVAGLSSTSQFTSSSQLDETSQLWAQPDTVPVS----VPADIRFSVWISFFEIYNELLYDLLEPPS-----HQHKRQTLRLC-EDQNGNPYVKDLNWIHVRDVEEAWKLLKVGRKNQSFASTHMNQQSSRSHSIFSIRILHLQGEGDIVPKISELSLCDLAGSERCKHQ-KSGERLKEAGNINTSLHTLGRCIAALRQNQQN---RSKQ-NLIPFRDSKLTRVFQGFFTGRGRSCMIVNVNPCASTYDETLHAAKFSALASQLVHAPPVHLGIPSLHSFIKKHSPQVGPGLEKEDKADSDLEDSPEDEADVSVYGKEELLQVVEAMKALLLKERQEKLQLEIQLREEICNEMVEQMQQREQWCSERLDNQKELMEELYEEKLKILKESLTTFYQEQIQERDEKIEELETLLQEAKQQ-PAAQQS----GGLSLLRRSQRLAASAS------TQQFQEVKAELEQCKTELSS-------TTAELHKYQQVLKPPPPAKPFTIDVDKKLEEGQKNIRLLRTELQKLGQSLQSAERACCHSTGAGKLRQALTNCDDILIKQNQTLAELQNNMVLVKLDLQKKAACIAEQYHTVLKLQGQASAK----KRLGANQENQQPNHQPPGKKPFLRNLLP-RTP-------TCQSSTDSSPYARILRSRH-SPLLKS-PFGKKY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95235-1", "uniprot_id": "KI20A_HUMAN", "id": "O95235-1", "name": "Kinesin-like protein KIF20A", "aln": "MSQGILSPPAGLLSDDDVVVSPMFESTAADLGSVVRKN----LLSDCS-VVSTSLE--------------DKQQVPSEDSMEKVKVYLRVRPLLPSELERQEDQGCVRIENVETLVLQAPKDSFALKSNERGIGQATHRFTFSQIFGPEVGQASFFNLTVKEMVKDVLKGQNWLIYTYGVTNSGKTHTIQGTIKDGGILPRSLALIFNSLQGQLHPTPDLKPLLSNEVIWLDSKQIRQEEMKKLSLLNGGLQEEELSTSLKRSVYIESRIGTSTSFDSGIAGLSSISQCTSSSQLDETSHRWAQPDTAPLP----VPANIRFSIWISFFEIYNELLYDLLEPPS-----QQRKRQTLRLC-EDQNGNPYVKDLNWIHVQDAEEAWKLLKVGRKNQSFASTHLNQNSSRSHSIFSIRILHLQGEGDIVPKISELSLCDLAGSERCKDQ-KSGERLKEAGNINTSLHTLGRCIAALRQNQQN---RSKQ-NLVPFRDSKLTRVFQGFFTGRGRSCMIVNVNPCASTYDETLHVAKFSAIASQLVHAPPMQLGFPSLHSFIKEHSLQVSPSLEKGAKADTGLDDDIENEADISMYGKEELLQVVEAMKTLLLKERQEKLQLEMHLRDEICNEMVEQMQQREQWCSEHLDTQKELLEEMYEEKLNILKESLTSFYQEEIQERDEKIEELEALLQEARQQSVAHQQS----GSELALRRSQRLAASAS------TQQLQEVKAKLQQCKAELNS-------TTEELHKYQKMLEPPPSAKPFTIDVDKKLEEGQKNIRLLRTELQKLGESLQSAERACCHSTGAGKLRQALTTCDDILIKQDQTLAELQNNMVLVKLDLRKKAACIAEQYHTVLKLQGQVSAK----KRLGTNQENQQPNQQPPGKKPFLRNLLP-RTP-------TCQSSTDCSPYARILRSRR-SPLLKSGPFGKKY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QDF0-1", "uniprot_id": "F1QDF0_DANRE", "id": "F1QDF0-1", "name": "Kinesin-like protein", "aln": "---MALASPCGILSDEEECG-AVFESTAADVVGLMRSQRFVSPLPEIS-VITPAADSLTPTKELVQIKSDISRRGSTDDGSDKLKVFLRIRPLTEAEKDRGEEQGCVNVQSEDNLLLKAPKDSRNMKSAERGVAQSVHKFTFTKIFGPQTSQQEVYDHTIREMVRDVLRGENRLLYTYGVTNSGKTYTIQGAGAEAGLLPRALVSVFLKLSGRLYTAMDLKPVLSQEVRKLDVGEVRAEEMRRDALLK----EDESN---------QSRLRAGLSWDSGISGLSATSHIAT--QLEDSDGVCLEANGLCLSGGEDLEEGVQFSVWVSFYEIYNEFLYDLLDAPPS---LQSRKRVTLRLS-DDKHGNPYVKDLTWIQVHSAEEAWKVLKVGQRNQSFASTHLNHNSSRSHSIFTIRVLHVKPQLGQVTRISELSVCDLAGSERCKAQ-QNGERMKEANNINTSLLTLGRCITALRHNQTN---KSRPPVVVPFRDSKLTRVLQSFFCGHGRSCMVVNINPCASTYDETLQALKFSAIATQLVHGPCSKTRVAYILSLLREQ-----PTHPNDTTLLEEDEEESDEEGDITMFDPEALLKAIDVLKREVLRQRQEKEELEAKVREEVCTEMMEVISRMQDDFSETLESERDLMEKRCENKINNLKSSLKKYYSQELEERDDEIRELTAALKEKEAGNTAPAAIFPPLNDDGGLRRSQRLASTHKRDADHESIELFRCKAELENCRAELDLKQTELRLKTLELKRFQDNLPSMGVTGTLTTTAERKLEEGQRNLKQLRMELQLLGIKLQSGERACCRNTDGEKLRHALSSADSKLAKQDQMLVELHTSLQLVKAELRKKDELLTRFQNTQQAQSHQPPTASGSCKKRGCGVAVALAENQPPEKRPFFRSLFPSRTPSKTPSRPTRQQNEVTTPYSRVLRSRQPSPPTTPVMLRVKY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V877-1", "uniprot_id": "SUB_DROME", "id": "Q9V877-1", "name": "Kinesin-like protein subito", "aln": "----MDSKEVSEVPRREVRSFLMARDPSIDRRFRPRPNKKMRLFDNIQESEEESFSEYSDTESEYKYQSSEATEGASCATSAADSSNVETGPQVFLRLRPVKDASKAYIVSEEANVLIT---SCKVDSTSNNVNRMEKHFGFTSIFDSTVGQRDIYDTCVG---PKIMEEECVTIMTYGTSGSGKTYTLLGDDVRAGIIPRALENIFTIYQDTVFRSPKLKLINGSIVFLQDDASLKELQIRKKLLDLCP---------------------------------DISAHHQRLKQVIDGDHMFETKASTDVS----------VLVWVSFVEIYNELVYDLLAIPPKQDKLGEVPRKNLKIV-GNK-GHVFIKGLTSVFVTSSEEALRLLRLGQQRSTYASTSVNANSSRSHCVFTVDILKYNRSG--ITTQSSYKFCDLAGSERVNNTGTSGLRLKEAKNINTSLMVLGRCLDAASTVQKK---KNAD--IIPYRDSKLTMLLQAALLGKEKLAMIVTVTPLDKYYEENLNVLNFASIAKNIIFKEPVIKQHRVSYCGFMEFS-----------------KMSTCEGGDYTKELEDENVRLQLEIEQLKYDHVLQMQLLEEKLRRELTATYQEIIQ-----------NNKKQYEDECEKKLLIAQRESEFMLSSQRRRYEEQIEDLKDEIEELKNPAS--------------------------------------------------------------------------------DTDISDDPNESKSPIEILDDD------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32364-1", "uniprot_id": "SMY1_YEAST", "id": "P32364-1", "name": "Kinesin-related protein SMY1", "aln": "-------MHWNIISKEQSSSSVSLP---------------------------------------------------TLDSSEPCHIEVILRAIPEKGLQ--NNESTFKIDPYENTVLFR-----TNNPLHETTKETHSTFQFDKVFDANATQEDVQKFLVHPIINDVLNGYNGTVITYGPSFSGKSYSLIGSKESEGILPNICKTLFDTLE-------------------------KNEETKGD----------------------------------------------------------------------------SFSVSVLAFEIYMEKTYDLLVPLP--------ERKPLKLHRSSSKMDLEIKDICPAHVGSYEDLRSYIQAVQNVGNRMACGDKTERSRSHLVFQLHVEQRNRKDD-ILKNSSLYLVDLHGAEKFDKRTESTLSQDALKKLNQSIEALKNTVRSLSMKERDSAYSAKGSHSSAYRESQLTEVLKDSLGGNRKTKVILTC--FLSNVPTTLSTLEFGDSIRQINNKVTDNTTGLNLKKKMDLFIQD---------------MKIKDDNYVAQINILKAEIDSLKSLHNKSLPEDDEKKMLENTKKENIKLKLQLDSITQLLSSSTNEDPNNRIDEEVSEILTKRCEQIAQLELSFDRQMNSNSKLQQELEYKKSKEEALES-----------------------------------------------------------------------------MNVRLLEQIQLQEREIQELLTTNAILKGELETHTKLTETRS--ERIKSLESSVKELSLNKSAIPSPRRGSMSSSSGNTMLHIEEGSEISNSPWSANTSSKPLVWGARKVSSSSIATTGSQESFVARPFKKGLNLHSIK--------VTSSTPKSPSSGS-------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :. : : . :: . : : :* .. . . * * .:*.. . * . . : .::. : *** : ***:::: * *::*. :* . : : : . : : *** * **** . * *:: .. . :*.: * . *: :: :. . : : : **** :* : : : : . : *. . ** *:*: . . . ::* *: .* . : : : . .:*:*:** ::: : *. : :::. . .* . :*. :: : : . : :. . : ** : :: :. *. * : . : . .:. : :: . . : : :. * ", "identical_positions": 53, "similar_positions": 138, "identity": "5.56%" }, { "cls_id": "homologset.agr.MGI:1201683", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZY52-1", "uniprot_id": "D3ZY52_RAT", "id": "D3ZY52-1", "name": "", "aln": "MQLGEQLLVSSVNLPGAHFYSLESARGGGGGGGGGGGGGGGGSASLLPGAAPSPQRLDLDKASKKFPGSLPCQAGSAEPAGAGAGAPAAMLSDADAGDTFGSASAVAKPGPPDGRKGSPCAEEELP--------SAATAAATARYSMDSLSSERYYLPSPGPQGSELAAPCSLFQYPAAAGAAHGSVYPASNGARYPYGSMLPPGGFPAAVCPPARSQFGPATGSGSGAGSSGGGAGGPGGYPYGQGSPLYGPYAGTSAAGSCGGLGGLGVPGSGFRAHVYLCNRPLWLKFHRHQTEMIITKQGRRMFPFLSFNINGLNPTAHYNVFVEVVLADPNHWRFQGGKWVTCGKADNNMQGNKMYVHPESPNTGSHWMRQEISFGKLKLTNNKGANNNNTQMIVLQSLHKYQPRLHIVEVTEDGVEDLNEPSKTQTFTFSETQFIAVTAYQNTDITQLKIDHNPFAKGFRDNYDSMYTASENDRLTPSPTDSPRSHQIVPGGRYGVQNFFPEPFVNTLPQARYYNGERTVPQTNGLLSPQQSEEVANPPQRWLVTPVQQPVTNKLDIGSYESEYSSSTLLPYGIKSLPLQTSHALGYYPDPTFPAMAGWGGRGAYQRKMAAGLPWTSRMSPPVFPEDQLAKEKVKEEISSSWVETPPSIKSLDSNDSGVYNSACKRKRLSPTTSSNGNSPPIKCEDINTEEYSKDTSKGMGAYYAFYTTP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O54839-1", "uniprot_id": "EOMES_MOUSE", "id": "O54839-1", "name": "Eomesodermin homolog", "aln": "MQLGEQLLVSSVNLPGAHFYSLESARGGGGGGGGGGGGGGG-SVSLLPGAAPSPQRLDLDKASKKFPGSLPCQAGSAEPAGAGAGAPAAMLSDADAGDTFGSTSAVAKPGPPDGRKGSPCAEEELP--------SAATAAATARYSMDSLSSERYYLPSPGPQGSELAAPCSLFQYPAAAGAAHGPVYPASNGARYPYGSMLPPGGFPAAVCPPARAQFGPAAGSGSGAGSSGGGAGGPGAYPYGQGSPLYGPYAGTSAAGSCGGLGGLGVPGSGFRAHVYLCNRPLWLKFHRHQTEMIITKQGRRMFPFLSFNINGLNPTAHYNVFVEVVLADPNHWRFQGGKWVTCGKADNNMQGNKMYVHPESPNTGSHWMRQEISFGKLKLTNNKGANNNNTQMIVLQSLHKYQPRLHIVEVTEDGVEDLNEPSKTQTFTFSETQFIAVTAYQNTDITQLKIDHNPFAKGFRDNYDSMYTASENDRLTPSPTDSPRSHQIVPGGRYGVQNFFPEPFVNTLPQARYYNGERTVPQTNGLLSPQQSEEVANPPQRWLVTPVQQPVTNKLDIGSYESEYTSSTLLPYGIKSLPLQTSHALGYYPDPTFPAMAGWGGRGAYQRKMAAGLPWTSRMSPPVFPEDQLAKEKVKEEISSSWIETPPSIKSLDSSDSGVYNSACKRKRLSPSTPSNGNSPPIKCEDINTEEYSKDTSKGMGAYYAFYTSP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95936-1", "uniprot_id": "EOMES_HUMAN", "id": "O95936-1", "name": "Eomesodermin homolog", "aln": "MQLGEQLLVSSVNLPGAHFYPLESARGGSGG-----------SAGHLPSAAPSPQKLDLDKASKKFSGSLSCEAVSGEPAAASAGAPAAMLSDTDAGDAFASAAAVAKPGPPDGRKGSPCGEEELPSAAAAAAAAAAAAAATARYSMDSLSSERYYLQSPGPQGSELAAPCSLFPYQAAAGAPHGPVYPAPNGARYPYGSMLPPGGFPAAVCPPGRAQFGPGAGAGSGAGGSSGGGGGPGTYQYSQGAPLYGPYPGAAAAGSCGGLGGLGVPGSGFRAHVYLCNRPLWLKFHRHQTEMIITKQGRRMFPFLSFNINGLNPTAHYNVFVEVVLADPNHWRFQGGKWVTCGKADNNMQGNKMYVHPESPNTGSHWMRQEISFGKLKLTNNKGANNNNTQMIVLQSLHKYQPRLHIVEVTEDGVEDLNEPSKTQTFTFSETQFIAVTAYQNTDITQLKIDHNPFAKGFRDNYDS-------------------SHQIVPGGRYGVQSFFPEPFVNTLPQARYYNGERTVPQTNGLLSPQQSEEVANPPQRWLVTPVQQPGTNKLDISSYESEYTSSTLLPYGIKSLPLQTSHALGYYPDPTFPAMAGWGGRGSYQRKMAAGLPWTSRTSPTVFSEDQLSKEKVKEEIGSSWIETPPSIKSLDSNDSGVYTSACKRRRLSPSNSSNENSPSIKCEDINAEEYSKDTSKGMGGYYAFYTTP", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "********************.*******.** *.. **.******:**********.***.*:* *.***.*.**********:****:*.*::****************.***** :**:******************* **************** * *****.**.****.***********************.*:****.:*:*****.*.**.**** * *.**:******.*::********************************************************************************************************************************************************************************************************************* *************.**************************************************** ******.******:**************************************:************** **.**.****:********.***:***********.*****.*****:****:..** ***.*******:************.******:*", "identical_positions": 613, "similar_positions": 55, "identity": "85.61%" }, { "cls_id": "homologset.agr.MGI:1201684", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O70300-1", "uniprot_id": "PSPN_MOUSE", "id": "O70300-1", "name": "Persephin", "aln": "MAAGRLRILCLLLLSLHPSLGWVLDLQEASVAD-KLSFGKMAETRGTWTPHQGNNHVRLPRALAGSCRLWSLTLPVAELGLGYASEEKVIFRYCAGSCPQEARTQHSLVLARLRGRGRAHGRPCCQPTSYADVTFLDDQHHWQQLPQLSAAACGCGG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O70301-1", "uniprot_id": "PSPN_RAT", "id": "O70301-1", "name": "Persephin", "aln": "MAAGRLRILFLLLLSLHLGLGWVLDLQEAPAAD-ELSSGKMAETGRTWKPHQGNNNVRLPRALPGLCRLWSLTLPVAELGLGYASEEKIIFRYCAGSCPQEVRTQHSLVLARLRGQGRAHGRPCCQPTSYADVTFLDDHHHWQQLPQLSAAACGCGG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O60542-1", "uniprot_id": "PSPN_HUMAN", "id": "O60542-1", "name": "Persephin", "aln": "MAVGKFLLGSLLLLSLQLGQGWGPDARGVPVADGEFSSEQVAKAGGTWLGTHR-PLARLRRALSGPCQLWSLTLSVAELGLGYASEEKVIFRYCAGSCPRGARTQHGLALARLQGQGRAHGGPCCRPTRYTDVAFLDDRHRWQRLPQLSAAACGCGG", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.*:: : ******: . ** * : ...** ::* ::*:: ** : .** ***.* *:******.*************:**********: .****.*.****:*:***** ***:** *:**:****:*:**:*************", "identical_positions": 97, "similar_positions": 34, "identity": "61.78%" }, { "cls_id": "homologset.agr.MGI:1201685", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q13363-1", "uniprot_id": "CTBP1_HUMAN", "id": "Q13363-1", "name": "C-terminal-binding protein 1", "aln": "------MGSSHLLNKGLPLGVRPPIMNGPLHPRPLVALLDGRDCTVEMPILKDVATVAFCDAQSTQEIHEKVLNEAVGALMYHTITLTREDLEKFKALRIIVRIGSGFDNIDIKSAGDLGIAVCNVPAASVEETADSTLCHILNLYRRATWLHQALREGTRVQSVEQIREVASGAARIRGETLGIIGLGRVGQAVALRAKAFGFNVLFYDPYLSDGVERALGLQRVSTLQDLLFHSDCVTLHCGLNEHNHHLINDFTVKQMRQGAFLVNTARGGLVDEKALAQALKEGRIRGAALDVHESEPFSFSQGPLKDAPNLICTPHAAWYSEQASIEMREEAAREIRRAITGRIPDSLKNCVNKDHLTAATHWASMD--PAVVHP--ELNGAAY-RYPPG------VVGVAPTGIP---AAVEGIVPSAMSLSHGLPPVAHPPHAPSPG---------QTVKPEADR-DHASDQL------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O88712-1", "uniprot_id": "CTBP1_MOUSE", "id": "O88712-1", "name": "C-terminal-binding protein 1", "aln": "------MGSSHLLNKGLPLGVRPPIMNGPMHPRPLVALLDGRDCTVEMPILKDVATVAFCDAQSTQEIHEKVLNEAVGALMYHTITLTREDLEKFKALRIIVRIGSGFDNIDIKSAGDLGIAVCNVPAASVEETADSTLCHILNLYRRTTWLHQALREGTRVQSVEQIREVASGAARIRGETLGIIGLGRVGQAVALRAKAFGFNVLFYDPYLSDGIERALGLQRVSTLQDLLFHSDCVTLHCGLNEHNHHLINDFTVKQMRQGAFLVNTARGGLVDEKALAQALKEGRIRGAALDVHESEPFSFSQGPLKDAPNLICTPHAAWYSEQASIEMREEAAREIRRAITGRIPDSLKNCVNKDHLTAATHWASMD--PAVVHP--ELNGAAYSRYPPG------VVSVAPTGIP---AAVEGIVPSAMSLSHGLPPVAHPPHAPSPG---------QTVKPEADR-DHTSDQL------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Z2F5-1", "uniprot_id": "CTBP1_RAT", "id": "Q9Z2F5-1", "name": "C-terminal-binding protein 1", "aln": "------MS-----------GVRPPIMNGPMHPRPLVALLDGRDCTVEMPILKDVATVAFCDAQSTQEIHEKVLNEAVGALMYHTITLTREDLEKFKALRIIVRIGSGFDNIDIKSAGDLGIAVCNVPAASVEETADSTLCHILNLYRRTTWLHQALREGTRVQSVEQIREVASGAARIRGETLGIIGLGRVGQAVALRAKAFGFNVLFYDPYLSDGIERALGLQRVSTLQDLLFHSDCVTLHCGLNEHNHHLINDFTVKQMRQGAFLVNTARGGLVDEKALAQALKEGRIRGAALDVHESEPFSFSQGPLKDAPNLICTPHAAWYSEQASIEMREEAAREIRRAITGRIPDSLKNCVNKDHLTAATHWASMD--PAVVHP--ELNGAAYSRYPPG------VVSVAPTGIP---AAVEGIVPSAMSLSHGLPPVAHPPHAPSPG---------QTVKPEADR-DHTTDQL------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A2R8QPP7-1", "uniprot_id": "A0A2R8QPP7_DANRE", "id": "A0A2R8QPP7-1", "name": "", "aln": "-----------------MQGIRPPIMNGPMHPRPLVALLDGRDCTVEMPILKDVATVAFCDAQSTQEIHEKVLNEAVGALMYHTITLMREDLEKFKALRIIVRIGSGFDNIDIKSAGDLGIAVCNMPAASVEETADSTMCHILNLYRRTTWLHQALREGTRVQSVEQIREVASGAARIRGETLGIIGLGRVGQAVALRAKAFGFSVIFYDPYLSDGMERALGLQRVNTLQDLLFHSDCVTLHCSLNEHNHHLINDFTIKQMRQGAFLVNTARGGLVDEKALAQALKEGRIRGAALDVHETEPFSFSQGPLKDAPNLICTPHAAWYSEQASIEMREEAAREIRRAITGRIPDSLKNCVNKEFLTQTTHWAGMD--PAVVHP--ELN-GAY-RYPPG------VVSHASGGLP---PPVEGIMPSAVPITHSLPTVAHPPHAPSPG---------QTGKPEPDREQHPNEQL------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1PBY6-1", "uniprot_id": "A0A8M1PBY6_DANRE", "id": "A0A8M1PBY6-1", "name": "", "aln": "MALMDKHKVKRQRLDRICEGIRPPILNGPMHPRPLVALLDGRDCTVEMPILKDVATVAFCDAQSTQEIHEKVLNEAVAALLYHTITLSRDDLDKFKGLRVIVRIGSGFDNVDIKAAAELGIAVCNVPAASVEETADTAMCLILNLYRRVTWMHQALREGTRASSVEQIREVAGGAARIRGETLGIIGLGRVGQAVALRAKAFGFGVIFYDPYLPDGVERSLGLQRMATLQDLLMHSDCVSLHCSLNEHNHHLINDFTIKQMRQGAFLVNTARGGLVDEKALAQALKEGRIRGAALDVHETEPFSFSQGPLKDAPNLICTPHTSWYSEQASIEAREEAAREVRRAITGRIPDSLKNCVNKEYLMAASQWPSME--ATTVHS--ELNGAAAYRFPAG------LIGVAAGGLPGAGAGVEGIVAGSLPLAHAIAPVSHPPHTPSPG---------QPSKAEADR-DIPSDQ-------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O46036-1", "uniprot_id": "CTBP_DROME", "id": "O46036-1", "name": "C-terminal-binding protein", "aln": "------MDKNLMMPKRSRIDVKGNFANGPLQARPLVALLDGRDCSIEMPILKDVATVAFCDAQSTSEIHEKVLNEAVGALMWHTIILTKEDLEKFKALRIIVRIGSGTDNIDVKAAGELGIAVCNVPGYGVEEVADTTMCLILNLYRRTYWLANMVREGKKFTGPEQVREAAHGCARIRGDTLGLVGLGRIGSAVALRAKAFGFNVIFYDPYLPDGIDKSLGLTRVYTLQDLLFQSDCVSLHCTLNEHNHHLINEFTIKQMRPGAFLVNTARGGLVDDETLALALKQGRIRAAALDVHENEPYNVFQGALKDAPNLICTPHAAFFSDASATELREMAATEIRRAIVGNIPDVLRNCVNKEYFMRTPPAAAAGGVAAAVYPEGALHHRAHSTTPHDGPHSTTNLGSTVGGGPTTVAQAAAAAVAAAAAAALLPSPVPSHLSPQVGGLPLGIVSSQSPLSAPDPNNHLSSSIKTEVKAESTEAP", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:: : ***::.************::*******************.***********.**::*** * ::**:***.**:******* **:*:*:*.:*******:*. .***.**:::* *******. *: : :***.: . **:**.* *.*****:***::****:*.***********.*:******.**::::*** *: ******::****:*** **********:**:**** **************:::** ***:****.*******.**:.. **.************::::*: :: * ** ** *:****.*.*** *:*****:.: :. .. .:.*:. *: * * . :. : * * . . . .: . : :.. . :*. * *. . .* : ... ", "identical_positions": 244, "similar_positions": 116, "identity": "50.62%" }, { "cls_id": "homologset.agr.MGI:1201686", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P56545-1", "uniprot_id": "CTBP2_HUMAN", "id": "P56545-1", "name": "C-terminal-binding protein 2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MALVDKHKVKRQ-------RLDRICEGIRPQIMNGPLHPRPLVALLDGRDCTVEMPILKDLATVAFCDAQSTQEIHEKVLNEAVGAMMYHTITLTREDLEKFKALRVIVRIGSGYDNVDIKAAGELGIAVCNIPSAAVEETADSTICHILNLYRRNTWLYQALREGTRVQSVEQIREVASGAARIRGETLGLIGFGRTGQAVAVRAKAFGFSVIFYDPYLQDGIERSLGVQRVYTLQDLLYQSDCVSLHCNLNEHNHHLINDFTIKQMRQGAFLVNAARGGLVDEKALAQALKEGRIRGAALDVHESEPFSFAQGPLKDAPNLICTPHTAWYSEQASLEMREAAATEIRRAITGRIPESLRNCVNKEFFVTSAPWS--------VIDQQAIHPELNGATYRYPPG---IVGVAPGG-------------LPAAMEGIIPGGIPVTHN---------LPTVAHPSQAPSPNQPTKHGDNREHPNEQ----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P56546-1", "uniprot_id": "CTBP2_MOUSE", "id": "P56546-1", "name": "C-terminal-binding protein 2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MALVDKHKVKRQ-------RLDRICEGIRPQIMNGPLHPRPLVALLDGRDCTVEMPILKDLATVAFCDAQSTQEIHEKVLNEAVGAMMYHTITLTREDLEKFKALRVIVRIGSGYDNVDIKAAGELGIAVCNIPSAAVEETADSTVCHILNLYRRNTWLYQALREGTRVQSVEQIREVASGAARIRGETLGLIGFGRTGQAVAVRAKAFGFSVIFYDPYLQDGIERSLGVQRVYTLQDLLYQSDCVSLHCNLNEHNHHLINDFTIKQMRQGAFLVNAARGGLVDEKALAQALKEGRIRGAALDVHESEPFSFAQGPLKDAPNLICTPHTAWYSEQASLEMREAAATEIRRAITGRIPESLRNCVNKEFFVTSAPWS--------VIDQQAIHPELNGATYRYPPG---IVGVAPGG-------------LPPAMEGIIPGGIPVTHN---------LPTVAHPSQAPSPNQPTKHGDNREHPNEQ----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9EQH5-1", "uniprot_id": "CTBP2_RAT", "id": "Q9EQH5-1", "name": "C-terminal-binding protein 2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MALVDKHKVKRQ-------RLDRICEGIRPQIMNGPLHPRPLVALLDGRDCTVEMPILKDLATVAFCDAQSTQEIHEKVLNEAVGAMMYHTITLTREDLEKFKALRVIVRIGSGYDNVDIKAAGELGIAVCNIPSAAVEETADSTVCHILNLYRRNTWLYQALREGTRVQSVEQIREVASGAARIRGETLGLIGFGRTGQAVAVRAKAFGFSVIFYDPYLQDGIERSLGVQRVYTLQDLLYQSDCVSLHCNLNEHNHHLINDFTIKQMRQGAFLVNAARGGLVDEKALAQALKEGRIRGAALDVHESEPFSFAQGPLKDAPNLICTPHTAWYSEQASLEMREAAATEIRRAITGRIPESLRNCVNKEFFVTSTPWS--------VIDQQAIHPELNGATYRYPPG---IVGVAPGG-------------LPPAMEGIIPGGIPVTHN---------LPTVAHPSQAPSPNQPTKHGDNREHPNEQ----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0AB32T658-1", "uniprot_id": "A0AB32T658_DANRE", "id": "A0AB32T658-1", "name": "C-terminal-binding protein 2", "aln": "MVSSFLLPSPPAVFPRLIIQRSPSERSHLIARPFHCDRDGTQKLLLDLSKQLPIGRSQSWDTLGGNEGHWERSDSVYEQQARMAGRRNSLSYGADAGGGWYEPAPGVRPPDLDLKREPEAYQESLYNQGYLDRPDPRNIRKSSVPELNSHYDRPPIAHRGTMPPHDYYQQDPGMPSRPTEGFYRGEQPHSLNRSSSHYGMMAGPRQIWEQGSGGRPGSVAPTPGVPPPPPPTVHDMGRIYRDPMLSGPLPATPGTKMMHEGQRIPSRAQSPARYIMEPNSPRYAAEPPASLTSHTVYSDVNGRPIDPHQPTATCLVVDPVAQGMDGTSRGMVMHPENPSPYTIQQQQQAQQQQQMQQQIQQQQMQQVQPVQQMQQVQPVQQMQQVQPVQQMQQAQPVQQMQQAQPVQQMQPVQPVQQMQPVQQVQQVPQVQPVQQVPHVQPVASPNPIYTPVPPVAPAPVTTPGVAVIPAPLPQLPAQPLTAAPPPSVPQTPVAPVDPKKNADPEFLALLHKEGLSESTINSLLQQGFDSTAMLAVMEENDVRSVAPNLGQARVLSRVVLCCKRPPEIVPATPLHPSAPARGRSNSFSHRSDIYVHQPPPLTPGLESQYIQPPSTPMQTMSPRIGDGYSRRPSSAPSQQLLETSGYPGPRVSGVYSGAMVPVQPRPLSGYNPHSGLPVTAMSQQVAIPAHLPGIQQQMAALPPQIHAMPLPALSAVPQSMTVPALAPQQAPKAYTTNYTVPMELMKRDRSLATMSPMPSPHLSPQVMRKAGVSSDGALVPIGGAVPGQNMNLANQKLSRRTGPPVIVSTMASPDTSIRPQIMNGPMHPRPLVALLDGRDCTVEMPILKDLATVAFCDAQSTQEIHEKVLNEAVGAMMYHTITLTREDLEKFKALRIIIRIGSGYDNIDIKAAGEMGIAVCNIPSAAVEETADSTLCHILNLYRRNTWLYQAMREGTRVQSVEQIREVASGAARIRGETLGLIGFGRSGQAVAVRAKAFGFNVIFYDPYLQDGLERSLGVQRVYTLQDLLYQSDCVSLHCNLNEHNHHLINDFTIKQMRQGAFLVNTARGGLVDEKALAQALKEGRIRGAALDVHESEPFSFTQGPLKDAPNLICTPHTAWYSEQASLEMREAAATEIRRAITGRIPDSLRNCVNKEFFVTTAPWG--------VMEQQ-VHPELNGGAYRFPPG---AVGVSPGG-------------MGGQIEGMMPGGLPSAHP---------LPPGTQPSLAPSPTQLLKHNDHREHLAKS----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O46036-1", "uniprot_id": "CTBP_DROME", "id": "O46036-1", "name": "C-terminal-binding protein", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDKNLMMPK----------RSRIDVKGNFANGPLQARPLVALLDGRDCSIEMPILKDVATVAFCDAQSTSEIHEKVLNEAVGALMWHTIILTKEDLEKFKALRIIVRIGSGTDNIDVKAAGELGIAVCNVPGYGVEEVADTTMCLILNLYRRTYWLANMVREGKKFTGPEQVREAAHGCARIRGDTLGLVGLGRIGSAVALRAKAFGFNVIFYDPYLPDGIDKSLGLTRVYTLQDLLFQSDCVSLHCTLNEHNHHLINEFTIKQMRPGAFLVNTARGGLVDDETLALALKQGRIRAAALDVHENEPYNVFQGALKDAPNLICTPHAAFFSDASATELREMAATEIRRAIVGNIPDVLRNCVNKEYFMRTPPAAAAGGVAAAVYPEGALHHRAHSTTPHDGPHSTTNLGSTVGGGPTTVAQAAAAAVAAAAAAALLPSPVPSHLSPQVGGLPLGIVSSQSPLSAPDPNNHLSSSIKTEVKAESTEAP", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::: .:: :: ***::.************::*******:***********.*************:*:*** **:**********:*:***** **:*:*****:******:*. .***.**:*:* *******. ** : :***.:. . **:**.* *.*****:****:*:** *.***:*******.******** **:::***: *********:*********.**********:******* ******:*******:::** ***:****.*******.**:.. **.************:*::*: :: *:** *********.*.**: ********:*: :.* . * : :* . :. : : * :* : ** .::*. :* : . * **.*.: . . : * :. ", "identical_positions": 264, "similar_positions": 102, "identity": "20.66%" }, { "cls_id": "homologset.agr.MGI:1201689", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9R233-1", "uniprot_id": "TPSN_MOUSE", "id": "Q9R233-1", "name": "Tapasin", "aln": "---------------------------------------------------MKPLLLLVAVALGLATVVSVVSAGPEAIECWFVEDAGGGGLSKKPATLLLRHGPRGPPPRPDLDPKLYFKVDDPAGMLLAAFRRYPAGASAPHCEMSRFIPFPASAKWARSLSPEQNCPRALDGDWLLVSVSSTLFSLSSLLRPQPEPLREPVVITMATVVLTVLTHNPAPRVQLGKDAVLDLRFAYAPSALEGSPSLDAGPPPFGLEWRRQHRGKGHLLLAATPGLAGRMPPAQEKATAFAAWDDD-EPWGPWTGNGTFWLPAVKPSQEGVYLATVHLPYLQGQVSLELTVHKAPRVSLTPAPVVWAAPGEAPPELLCLASHFFPAEGLEVKWELRGGPGGSSRKVEGKTWLSTIRHHSDGSVSQSGHLQLPPVTAKQHGVHYVCRVYHSSLPASGRSADVTLEVAGFSGPSIEDGIGLFLSAFLLLGLLKVLGWLAAYWTIPEVSKEKATAASLTIPRNSKKSQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LGP5-1", "uniprot_id": "A0ABK0LGP5_RAT", "id": "A0ABK0LGP5-1", "name": "", "aln": "MSEKANQGLTQGYLTNPGPEEEGGASGVLSYAGKRAVRSRERANVQGSGWSLRSGSQYWSMGKGLATVV--VSAGPQTIECWFVEDAGGGGLSKKPATLLLRHGPRGPPPRPDLDPKLYFKVDDPAGMLLAAFRRYPAGAHAPHCEMSSYIPFPASAKWARGLSPQQNCSRALDGDWLMVSVSGTVFSLSSLLRPLPEPQREPVFITMATVVLTVLTRHPAPRIHLGKDAVLDLRFAYAPPALEDAPSVASGPPPFGLEWRRQHRGKGHLLLAAIPGLLEKMPPAREKAVAFAAWDDDNDPWGPWTGNGTLWLPAVSPSQEGVYLATVHLPYLQGQVSLELTVHKPPRVSLTPAPIVWAAPGEAPPELLCLVSHFYPEEGLEVEWELRGGPEGSSRKAEGKTWVSTVRHHSDGSVSQSGHLQLPPVTDKQHGVRYACRVRHPSLPSSGRSAEVTLEVAGFSGPSIEDGIGLFLSAFLLLGLFKALGWMAAYLTIPKILKEKASATSLTVPKDEKKSE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O15533-1", "uniprot_id": "TPSN_HUMAN", "id": "O15533-1", "name": "Tapasin", "aln": "---------------------------------------------------MKSLSLLLAVALGLATAV---SAGPAVIECWFVEDASGKGLAKRPGALLLRQGPGEPPPRPDLDPELYLSVHDPAGALQAAFRRYPRGAPAPHCEMSRFVPLPASAKWASGLTPAQNCPRALDGAWLMVSISSPVLSLSSLLRPQPEPQQEPVLITMATVVLTVLTHTPAPRVRLGQDALLDLSFAYMPPTSEAASSLAPGPPPFGLEWRRQHLGKGHLLLAATPGLNGQMPAAQEGAVAFAAWDDD-EPWGPWTGNGTFWLPTVQPFQEGTYLATIHLPYLQGQVTLELAVYKPPKVSLMPATLARAAPGEAPPELLCLVSHFYPSGGLEVEWELRGGPGGRSQKAEGQRWLSALRHHSDGSVSLSGHLQPPPVTTEQHGARYACRIHHPSLPASGRSAEVTLEVAGLSGPSLEDSVGLFLSAFLLLGLFKALGWAAVYLSTCKDSKKKAE--------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::. ::. ****.* **** .*********.* **:*:*.:****:** *********:**:.*.**** * ******* ** ******* ::*:******* .*:* ***.***** **:**:*..::******** *** :***.************: ****::**:**:*** *** *.: * :.*: .************* ********* *** :**.*:* *.******** :**********:***:*.* ***.****:*********:***:*:*.*:*** **.:. *************.***:* ****:******* * *:*.**: *:*::********* ***** **** :***.:*.**: *.***:*****:*******:****:**.:************:*.*** *.* : : *:** ", "identical_positions": 310, "similar_positions": 88, "identity": "59.96%" }, { "cls_id": "homologset.agr.MGI:1201690", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7TSJ2-1", "uniprot_id": "MAP6_MOUSE", "id": "Q7TSJ2-1", "name": "Microtubule-associated protein 6", "aln": "MAWPCITRACCIARFWNQLDKADIAVPLVFTKYSEATEHPGAPPQPPAP---LQPALAPP-SRAVAIETQPAQGESDAVARATGPAPGPSVDRETVAAPGRSGLGLGAASASTSGSGPADSVMRQDYRAWKVQRPEPSCRPRSEYQPSDAPFERETQYQKDFRAWPLPRRGDHPWIPKPVQIPATSQPSQPVLGVPKRRPQSQERGPMQLSADARDPEGAGGAGVLAAGKASGVDQRDTRRKAGPAWMVTRNEGHEEKPLPPAQSQTQEGGPAAGKASGADQRDTRRKAGPAWMVTRSEGHEEKPLPPAQSQTQEGGPAAGKASGADQRDTRRKAG----------------------------------------------PAWMVTRTEGHEETPLPPAQSQTQEGGPAAGKASGADERDTRRKAGPAWMVRRSEGHEQTPAAHAQGTGPEGGKGRAVADALNRQIREEVASTVSSSYRNEFRAWTDIKPVKPIKAKPQYKPPD-DKMVHETSYSAQFKGEANKPSAADNKAMDRRRIRSLYSEPFKECPKVEKPSVQSSKPKKTSTSHKP----PRKAKDKQVVSGQAAKKKTTEGPSATKP--DDKEQSKEMNNKLAEAKESRVKPTSDASKNRGPVTKEPHKDQGSVAPGLPKGQ-----EPLKDQGPVVPGLPKDQVPVVPGSLKGQSPTAPGPTKDQGAVLLGPVKDLGPVAPAPIKVQDHIASELLKNKDSVPLAPAKAQSPLLPEPLKNQSPVVPASTKDQS------------------------FPTP-------APR--KDPGPVIPEPEKDRAPTVPERRKDQHVSIMASLKNEAPMVPESVKNQGLAGPELVKDTGTDTTAPRYLKGHDSVFVAPVKNQGPVIPEPVKSQDPIIPALAKDQGPMLPEPPKNQ-SPVVLGPIKNQDPIIPVPLKGQDPLVPAPTKDQGPTAPDPLKTQGPKGTQLPTVSPSPPVMIPTVPHTEYIEGSP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63560-1", "uniprot_id": "MAP6_RAT", "id": "Q63560-1", "name": "Microtubule-associated protein 6", "aln": "MAWPCITRACCIARFWNQLDKADIAVPLVFTKYSEATEHPGAPPQPPAP---PQPGLAPP-SRAVAIETQPAQGESDAVARATGPAPGPSGDRETAAAPGRSGLGLGAASGSTSGSGPADSVMRQDYRAWKVQRPEPSCRPRSEYQPSDAPFERETQYQKDFRAWPLPRRGDHPWIPKPVQIPATSQPSPPVLGMPKRRPQSQERGPIQLSADARDPEGAGGAGVPAAGKASGADQRDTRRKAGPAWMVTRTEGHEEKPLPPAQSQTQEGGPAAGKASGADQRDTRRKAGPAWMVTRTEGHEEKPLPPAQSQTQEGGPAAGKASGADQRDTRRKAGPAWMVTRTEGHEETPLPPAQSQTQEGGPAAGKASGADQRDTRRKAGPAWMVTRTEGHEETPLPPAQSQTQEGGPAAGKASGADERDTRRKAGPAWMVRRSEGHEQTTAAHAQGTGPEGGKGRAVADALNRQIREEVTSTVSSSYRNEFRAWTDIKPVKPIKAKPQYKPPD-DKMVHETSYSAQFKGEASKPTTADNKVVDRRRIRSLYSEPFKESPKVEKPSVQSSKPKKTSTSQKP----LRKAKDKQVASGQAAKKKTTESPSATKP--DDKEQSKEMNNKLAEAKESRVKPTSD--KNQGPVAKEPHKDQGPVAPGLPKGQGPAVQEPLKDQGPMVPGLPKDQAPVVPGSLKGQSPTAPGPPKDQGAVLLGPMKDLGPVAPASVKDQDHMASELLKNKDSVPLAPAKAQSPLLPEPLKNQSPVVPARAKDQS------------------------FPAP-------APTPLKDPGPVIPEPEKDGAPMVPERRKDQNASIMASLKNEAPVASESVKNQGLGGPEPAKDTGTD------LKGHGSVFVAPVKSQGPVVPEPTKGQDPIIPALAKDQGPILPEPPKNQGPPVVLGPIKNQDPVIPVPLKGQDPVVPAPTKDPGPTAPDPLKSQGPRGPQLPTVSPSPPVMIPTVPHAEYIEGSP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96JE9-1", "uniprot_id": "MAP6_HUMAN", "id": "Q96JE9-1", "name": "Microtubule-associated protein 6", "aln": "MAWPCITRACCIARFWNQLDKADIAVPLVFTKYSEATEHPGAPPQPPPPQQQAQPALAPPSARAVAIETQPAQGELDAVARATGPAPGPTGEREPAAGPGRSGPGPGLGSGSTSG--PADSVMRQDYRAWKVQRPEPSCRPRSEYQPSDAPFERETQYQKDFRAWPLPRRGDHPWIPKPVQISAASQASAPILGAPKRRPQSQERWPVQAAAEAREQEAAPGG---------------------------------------------AGGLAAGKASGADERDTRRKAGPAWIVRRAEG------------------------------------------------------------------------------------------LGHEQTPLPAAQAQVQ------------------------------------------ATGPEAGRGRAAADALNRQIREEVASAVSSSYRNEFRAWTDIKPVKPIKAKPQYKPPD-DKMVHETSYSAQFKGEASKPTTADNKVIDRRRIRSLYSEPFKEPPKVEKPSVQSSKPKKTSASHKP----TRKAKDKQAVSGQAAKKKSAEGPSTTKP--DDKEQSKEMNNKLAEAKESLAQPVSDSSKTQGPVATEPDKDQGSVVPGLLKGQGPMVQEPLKKQGSVVPGPPKDLGPMIPLPVKDQDHTVPEPLKNESPVISAPVKDQGPSVPVPPKNQSPMVPAKVKDQGSVVPESLKDQGPRIPEPVKNQAPMVPAPVKDEGPMVSASVKDQGPMVSAPVKDQGPIVPAPVKGEGPIVPAPVKDEGPMVSAPIKDQDPMVPEHPKDESAMATAPIKNQGSMVSEPVKNQGLVVSGPVKD--QDVVVPEHAKVHDSAVVAPVKNQGPVVPESVKNQDPILPVLVKDQGPTVLQPPKNQ-GRIVPEPLKNQVPIVPVPLKDQDPLVPVPAKDQGPAVPEPLKTQGPRDPQLPTVSPLPRVMIPTAPHTEYIESSP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F624-1", "uniprot_id": "E7F624_DANRE", "id": "E7F624-1", "name": "", "aln": "MAWPCISRACCMARFWSQLDKADIAVPLVFTKYSDVSEMQHLHLQ--------QPVQK------IAIETQPLHHDHEPVT------------RAPHAGHDEHSFG---------------SVMRQDFKHWKVR-PEPSCKPKNEYHGPEIPFNTETQYQKDYKPWPIPKKGDHPWIPKPSPSIS-------------AGKHSSPEMMMDSGVEKSEIA----------------------------------------------------DKVPEKEILSSERKKRQVKKVAVVS-----------------------------------------------------------------------------------------------ENNAGVKLDRDAS------------------------------------------------AVEGKGRAAVDALNRQIKREVSS--GSSYRTEFKAYTDVKPVKLIRAKSQYKPPD-DKTDLETSYSATYRAYQSSQQPDDNKALERRRIRTLYHEPYRESSKVEKTSLPRSKPKKSSSTSATPGKPLKKSKEKQATSVRGSKKKSSENQPESRAVQADKEKSKEINNKLAEAKEVMLK------QYHYIQLCQPIRDIGWVQT-----------------------------------LKQHLWRCALPDPRECESGVGRVSDYYS-------------------------AGTSGGEPLVERPEPRSRGVVRFAPDVKY---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E7FFM0-1", "uniprot_id": "E7FFM0_DANRE", "id": "E7FFM0-1", "name": "", "aln": "MAWPCITRACCINRFWSELDKGDIAVPLVFTKYSDVAEVQHLHPQP-------KPVLSQK---PVATESHLAHSAHQEASS-----------RATHGAADAAAAASQDGSG--------ASVMREDFKAWSVR-PERSCKPRNQYQPSKTPFINETQYQKDYKPWPIPKKGDHPWIPKPTAAAAPCKAES------KFSKHEQAAAEMETGVEKCEIE----------------------------------------------------EKQHEKE--SKERRKK-VEKKEPVS-----------------------------------------------------------------------------------------------EAS---KMEKDV-------------------------------------------------AVEGKRRSAADALNRQIKQEVTS--GSSYRTEFKAYRDIKPVKPIKAKSQYKLLVGEKTNLETSYSATFKGEQAKPQTTDNKLMEHRRIRSLYSEPSKESSKVERHNLSLTKPKKTPSHSKT----VKKAKEKPVAGSQPAKKKTSVSNQEPKPEGGVTKKSKEMINRLAEAKD-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******:****: ***.:***.************:.:* * :* :* *:: : : .: * . .. . . . ****:*:: *.*: ** **:*:.:*: .. ** *******::.**:*::********* : :.. :: ..: : * :.:* .: : : . *: *:..*******:.**:* .****.**:*: *:**** *:**.*** :* ****** ::. . . *** :::****:** ** :* .***: .: :****:.: . :*:*:* ... : :***:: . .:. .::***: *:*****: ", "identical_positions": 141, "similar_positions": 112, "identity": "14.07%" }, { "cls_id": "homologset.agr.MGI:1201691", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88846-1", "uniprot_id": "RNF4_RAT", "id": "O88846-1", "name": "E3 ubiquitin-protein ligase RNF4", "aln": "-------------------------------------------------------------------------------------MSTRNPQRKRRGG-AVNSRQTQKRTRETTSTPEISLEAEPIELVETVGDEIVDLTCESLEP---------------------------------VVVDLTHNDSVVIVEERRR-----------PRRNGRRLRQDHADSCVVSSDDEELSKDKDVYVTTHTPRSTKDEGTTGLRPSGTVSCPICMDGYSEIVQNGRLIVSTECGHVFCSQCLRDSLKNANTCPTCRKKINHKRYHPIYI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QZS2-1", "uniprot_id": "RNF4_MOUSE", "id": "Q9QZS2-1", "name": "E3 ubiquitin-protein ligase RNF4", "aln": "-------------------------------------------------------------------------------------MSTRNPQRKRRGG-TVNSRQTQKRTRETTSTPEVSLETEPIELVETVGDEIVDLTCESLEP---------------------------------VVVDLTHNDSVVIVEERRR-----------PRRNGRRLRQDHADSCVVSSDDEELSRDKDVYVTTHTPRSTKDDGATGPRPSGTVSCPICMDGYSEIVQNGRLIVSTECGHVFCSQCLRDSLKNANTCPTCRKKINHKRYHPIYI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P78317-1", "uniprot_id": "RNF4_HUMAN", "id": "P78317-1", "name": "E3 ubiquitin-protein ligase RNF4", "aln": "-------------------------------------------------------------------------------------MSTR----KRRGG-AINSRQAQKRTREATSTPEISLEAEPIELVETAGDEIVDLTCESLEP---------------------------------VVVDLTHNDSVVIVDERRR-----------PRRNARRLPQDHADSCVVSSDDEELSRDRDVYVTTHTPRNARDEGATGLRPSGTVSCPICMDGYSEIVQNGRLIVSTECGHVFCSQCLRDSLKNANTCPTCRKKINHKRYHPIYI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58H6D8-1", "uniprot_id": "A0AC58H6D8_DANRE", "id": "A0AC58H6D8-1", "name": "", "aln": "-------------------------------------------------------------------------------------MSTTVTQRKRRTSSTTCSRRGNSKRNRAQMSQTVMETIDVLENDRTNSEDVVDLTCEGSEP---------------------------------AVVDLTNNDSIVVVEDG-----------------VQRRVWPCTESYVLSSDEEEES---SLRLSPGLLSSLRDSSRARSTP-GAISCPVCMDVYSEIMDSGRLMVSTKCGHLFCSQCIRDSLSRAHSCPTCRKKLTHKQYHPIYI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VNJ0-1", "uniprot_id": "Q9VNJ0_DROME", "id": "Q9VNJ0-1", "name": "", "aln": "MSDSTIFRFNSSILDQSADSNVSSSSSNSSVSDSSVDSHSSIESNSGHNTSVESQSSAESDSSADSHSSLERPSPVERDLSVESDSSSATNTSESSVGEASNQLQSPQSNNPLNMANLSVSTEDAHSQIRSLTQDVIQMEAELDRMNRYCEEVVAQIDTFATRTSTPTTRRIRRRTSPVEVIDLSHLDRAPPVRSARNRDPDAFIDLCTPEGPRSRTVNLHSNDSLTILPRRSAENDPVVDLDVASPPKRVNRDIDESQKEELYKCPICMDSVSKREP-----VSTKCGHVFCRECIETAIRATHKCPICNKKLTARQFFRIYL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: : . : . : . . : : . .: :::::: .* . *:**:: * * . * ::. : .. . : : . : . .**:*** *: ***:***:** :*:. :: ::.** *.**:. :::. **:", "identical_positions": 30, "similar_positions": 58, "identity": "9.26%" }, { "cls_id": "homologset.agr.MGI:1201692", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z0S9-1", "uniprot_id": "PRAF1_MOUSE", "id": "Q9Z0S9-1", "name": "Prenylated Rab acceptor protein 1", "aln": "-------MAAQKDQQKDAEGEGLSATTLLPKLIPSGAGREWLERRRATIRPWGTFVDQQRFSRPRNVGELCQRLVRNVEYYQSNYVFVFLGLILYCVVTSPMLLVALAVFFGACYILYLRTLQSKLVLFGREVSPAHQYALAGGVSFPFFWLAGAGSAVFWVLGATLVLIGSHAAFHQMEPADGEE---LQMEPV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O35394-1", "uniprot_id": "PRAF1_RAT", "id": "O35394-1", "name": "Prenylated Rab acceptor protein 1", "aln": "-------MAAQKDQQKDAEVEGLSATTLLPKLIPSGAGREWLERRRATIRPWGTFVDQQRFSRPRNVGELCQRLVRNVEYYQSNYVFVFLGLILYCVVTSPMLLVALAVFFGACYILYLRTLQSKLVLFGREVSPAHQYALAGGVSFPFFWLAGAGSAVFWVLGATLVLIGSHAAFHQIEPADGEE---LQMEPV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UI14-1", "uniprot_id": "PRAF1_HUMAN", "id": "Q9UI14-1", "name": "Prenylated Rab acceptor protein 1", "aln": "-------MAAQKDQQKDAEAEGLSGTTLLPKLIPSGAGREWLERRRATIRPWSTFVDQQRFSRPRNLGELCQRLVRNVEYYQSNYVFVFLGLILYCVVTSPMLLVALAVFFGACYILYLRTLESKLVLFGREVSPAHQYALAGGISFPFFWLAGAGSAVFWVLGATLVVIGSHAAFHQIEAVDGEE---LQMEPV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1Z823-1", "uniprot_id": "A1Z823_DROME", "id": "A1Z823-1", "name": "PRA1 family protein", "aln": "MAHTGGNLSGNMQPPPPSGGRFSVDMQSLPSLSNLPSPLQIFQMVRNSLRPWVVFFNINNFKTAISMQRLNSRVIRNLSYFQANYVFIFFVLMIYCLITAPCILLVILASAFGCHKLRVR--NSNITIVGQQLTPSQQIIALNLATAPVLFLVGAGAVLFWTLGASCFVIAMHAIFYNIDAIVTEENEGFLAQVV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53633-1", "uniprot_id": "PRA1_YEAST", "id": "P53633-1", "name": "Prenylated Rab acceptor 1", "aln": "-------------MNQLGALAQVSRFTQNFSMENIKSEFQSLQSKLATLRTPQEFFNFKKISKPQNFGEVQSRVAYNLKYFSSNYGLIIGCLSIYTLLTNLLLLFVIVLVVAGIVGINKLKGEELVTPFG-SFKTNQLYTGLVCVAVPIGFLASPISTLLWLIGASAVSVFGHASLMEKPIETVFD-----EETV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .: : : :: ::*. *.: :.:. . .. .: .*: *:.*:.:** ::: * :* ::* :*..: . : :. :. .* .... : : *. :*... :.::* :**: . : ** : : : : *", "identical_positions": 20, "similar_positions": 68, "identity": "10.26%" }, { "cls_id": "homologset.agr.MGI:1201778", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A1B0GWX7-1", "uniprot_id": "A0A1B0GWX7_RAT", "id": "A0A1B0GWX7-1", "name": "V-type proton ATPase subunit", "aln": "MSFFPELYFNVDNGYLEGLVRGLKAGVLSQADYLNLVQCETLEDLKLHLQSTDYGNFLANEAS-PLTVSVIDDKLKEKMVVEFRHMRNHAYEPLASFLDFITYSYMIDNVILLITGTLHQRSIAELVPKCHPLGSFEQMEAVNIAQTPAELYNAILVDTPLAAFFQDCIS-EQDLDEMNIEIIRNTLYKAYLESFYKFCT-LLGGTTADAMCPILEFEADRRAFIITINSFG-TELSKEDRAKLFPHCGRLYPEGLAQLARADDYEQVKNVADYYPEYKLLFEGAGSNP-GDKTLEDRFFEHEVKLNKLAFLNQFHFGVFYAFVKLKEQECRNIVWIAECIAQRHRAKIDNYIPIF--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P51863-1", "uniprot_id": "VA0D1_MOUSE", "id": "P51863-1", "name": "V-type proton ATPase subunit d 1", "aln": "MSFFPELYFNVDNGYLEGLVRGLKAGVLSQADYLNLVQCETLEDLKLHLQSTDYGNFLANEAS-PLTVSVIDDKLKEKMVVEFRHMRNHAYEPLASFLDFITYSYMIDNVILLITGTLHQRSIAELVPKCHPLGSFEQMEAVNIAQTPAELYNAILVDTPLAAFFQDCIS-EQDLDEMNIEIIRNTLYKAYLESFYKFCT-LLGGTTADAMCPILEFEADRRAFIITINSFG-TELSKEDRAKLFPHCGRLYPEGLAQLARADDYEQVKNVADYYPEYKLLFEGAGSNP-GDKTLEDRFFEHEVKLNKLAFLNQFHFGVFYAFVKLKEQECRNIVWIAECIAQRHRAKIDNYIPIF--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P61421-1", "uniprot_id": "VA0D1_HUMAN", "id": "P61421-1", "name": "V-type proton ATPase subunit d 1", "aln": "MSFFPELYFNVDNGYLEGLVRGLKAGVLSQADYLNLVQCETLEDLKLHLQSTDYGNFLANEAS-PLTVSVIDDRLKEKMVVEFRHMRNHAYEPLASFLDFITYSYMIDNVILLITGTLHQRSIAELVPKCHPLGSFEQMEAVNIAQTPAELYNAILVDTPLAAFFQDCIS-EQDLDEMNIEIIRNTLYKAYLESFYKFCT-LLGGTTADAMCPILEFEADRRAFIITINSFG-TELSKEDRAKLFPHCGRLYPEGLAQLARADDYEQVKNVADYYPEYKLLFEGAGSNP-GDKTLEDRFFEHEVKLNKLAFLNQFHFGVFYAFVKLKEQECRNIVWIAECIAQRHRAKIDNYIPIF--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PGV1-1", "uniprot_id": "VA0D1_DANRE", "id": "Q6PGV1-1", "name": "V-type proton ATPase subunit d 1", "aln": "-MPFSELYFNVDNGYLEGLVRGFKAGILSQADYLNLVQCETLEDLKLHLQSTDYGSFLANEAS-PLTVSVIDDKLKEKMVVEFRHMRNQSYEPLASFMDFITYSYMIDNVILLITGTLHQRAISELVPKCHPLGSFEQMEAVNIAQTPAELYNAILVDTPLAAFFQDCIS-EQDLDEMNIEIIRNTLYKAYLEAFYKFCT-TLGGTTADTMCPILEFEADRRAFIITINSFG-TELSKEDRAKLFPHCGKLYPEGLAQLARADDYEQVKAVAEYYPEYKLLFEGAGSNP-GDKTLEDRFFEHEVKLNKLAFLNQFHFSVFYAYVKLKEQECRNIVWIAECIAQRHRAKIDNYIPIF--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W4P5-1", "uniprot_id": "VA0D1_DROME", "id": "Q9W4P5-1", "name": "V-type proton ATPase subunit d 1", "aln": "-MNSSGFMFNIDNGYLEGLCRGFKCGILKQADYLNLVQCETLEDLKLHLQGTDYGSFLANEPS-PLSVSVIDDKLREKLVIEFQHMRNHAVEPLSNFLDFITYGYMIDNIILLITGTLHQRPISELIPKCHPLGSFEQMEAIHVASTPAELYNAVLVDTPLAPFFVDCIS-EQDLDEMNIEIIRNTLYKAYLEAFYNFCK-NMGGATADVMCEILAFEADRRAIIITINSFG-TELSKDDRAKLYPNCGKMYPDGLAALARADDYEQVKTVAEYYAEYAALFDGSGNNP-GDKTLEDKFFEHEVKLDVYAFLQQFHFGVFYAYLKLKEQECRNIVWIAECVAQKHRAKIDNYIPIF--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32366-1", "uniprot_id": "VA0D_YEAST", "id": "P32366-1", "name": "V-type proton ATPase subunit d", "aln": "---MEGVYFNIDNGFIEGVVRGYRNGLLSNNQYINLTQCDTLEDLKLQLSSTDYGNFLSSVSSESLTTSLIQEYASSKLYHEFNYIRDQSSGSTRKFMDYITYGYMIDNVALMITGTIHDRDKGEILQRCHPLGWFDTLPTLSVATDLESLYETVLVDTPLAPYFKNCFDTAEELDDMNIEIIRNKLYKAYLEDFYNFVTEEIPEPAKECMQTLLGFEADRRSINIALNSLQSSDIDPDLKSDLLPNIGKLYPLATFHLAQAQDFEGVRAALANVYEYRGFLETG--------NLEDHFYQLEMELCRDAFTQQFAISTVWAWMKSKEQEVRNITWIAECIAQNQRERINNYISVY--", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VCQ3-1", "uniprot_id": "VA0D2_DROME", "id": "Q9VCQ3-1", "name": "Probable V-type proton ATPase subunit d 2", "aln": "----MSMIFNTEYGYLEALTRGFKNGMLKHSDYLNLTQCESLEDVMISIQGTDYGLIFGGEQS-APSVEVIERCLRDRLLQQYYYIRSHSTEPLTTFMEFIRYPFMIDNVALLVAGLNNHRSMKRLLRMCHPLGEFDQLGAIEVASNSAELFDAVLIDTPIARFVPRDLP-MESLRYLDVEIVRAHLYRAYLEKFYAYCS-QLGGNTANVMTNLLSFEADRRTITIAVNAIG-SDIIPKERLKMFPTCGYLPKIALASMSTLNDTDKIRDVCNVFDGYGKMFDNLERDSDGMITLEDRFLMMEAKKNVQTFLQQYHFGIFYSFIKLKQLEVRNIVWISECIAQRQTDRINAFIPIPLD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . ** : *::*.: ** : *:*.: :*:**.**::***: : :..**** ::.. * . :..:*: .:: :: ::*.:: . .*:::* * :****: *:::* :.* .:: ***** *: : :: :* .*::::*:***:* :. : :.* :::**:* **:**** ** : . : : : * :* ******:: *::*:: ::: . : .: * * : . :: :* : :: . * ::: .***:* * : :* :*: :. .::::* *: * ***.**:**:**.: :*: :*.: ", "identical_positions": 93, "similar_positions": 132, "identity": "25.98%" }, { "cls_id": "homologset.agr.MGI:1201779", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AY09-1", "uniprot_id": "HNRH2_RAT", "id": "Q6AY09-1", "name": "Heterogeneous nuclear ribonucleoprotein H2", "aln": "--------------------------------------MMLSTEGREGFVVKVRGLPWSCSAEEVMRFFSDCKIQNGTSGVRFIYTRE-GRPSGEAFVELESEDEVKLALKKDRETMGHRYVEVFKSNSVEMDWVLKHTGPNSPDTANDGFVRLRGLPFGCSKEEIVQFFSGLEIVPN--GMTLPVDFQGRSTGEAFVQFASQEIAEKALKKHKERIGHRYIEIFKSSRAEVRTHYDPPRKLMTMQRPGPYDRP--GAGRGYNSIGRGA-----------------GFERMRRGAYGGGYGGYDDYGGYNDGYGFGSDRFGRDLNYCFSGMSDHRYGDGGSSFQSTTGHCVHMRGLPYRATENDIYNFFSPLNPMRVHIEIGPDGRVTGEADVEFATHEDAVAAMAKDKANMQHRYVELFLNSTAGTSGGAYDHSYVELFLNSTAGASGGAYGSQMMGGMGLSNQSSYGGPASQQLSAGYGG-----------------------------------GYGGQSSMSGYDQVLQE--------------------------------NSSDYQSNLA----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70333-1", "uniprot_id": "HNRH2_MOUSE", "id": "P70333-1", "name": "Heterogeneous nuclear ribonucleoprotein H2", "aln": "--------------------------------------MMLSTEGREGFVVKVRGLPWSCSAEEVMRFFSDCKIQNGTSGVRFIYTRE-GRPSGEAFVELESEDEVKLALKKDRETMGHRYVEVFKSNSVEMDWVLKHTGPNSPDTANDGFVRLRGLPFGCSKEEIVQFFSGLEIVPN--GMTLPVDFQGRSTGEAFVQFASQEIAEKALKKHKERIGHRYIEIFKSSRAEVRTHYDPPRKLMTMQRPGPYDRP--GAGRGYNSIGRGA-----------------GFERMRRGAYGGGYGGYDDYGGYNDGYGFGSDRFGRDLNYCFSGMSDHRYGDGGSSFQSTTGHCVHMRGLPYRATENDIYNFFSPLNPMRVHIEIGPDGRVTGEADVEFATHEDAVAAMAKDKANMQHRYVELFLNSTAGTSGGAYDHSYVELFLNSTAGASGGAYGSQMMGGMGLSNQSSYGGPASQQLSGGYGG-----------------------------------GYGGQSSMSGYDQVLQE--------------------------------NSSDYQSNLA----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P55795-1", "uniprot_id": "HNRH2_HUMAN", "id": "P55795-1", "name": "Heterogeneous nuclear ribonucleoprotein H2", "aln": "--------------------------------------MMLSTEGREGFVVKVRGLPWSCSADEVMRFFSDCKIQNGTSGIRFIYTRE-GRPSGEAFVELESEEEVKLALKKDRETMGHRYVEVFKSNSVEMDWVLKHTGPNSPDTANDGFVRLRGLPFGCSKEEIVQFFSGLEIVPN--GMTLPVDFQGRSTGEAFVQFASQEIAEKALKKHKERIGHRYIEIFKSSRAEVRTHYDPPRKLMAMQRPGPYDRP--GAGRGYNSIGRGA-----------------GFERMRRGAYGGGYGGYDDYGGYNDGYGFGSDRFGRDLNYCFSGMSDHRYGDGGSSFQSTTGHCVHMRGLPYRATENDIYNFFSPLNPMRVHIEIGPDGRVTGEADVEFATHEDAVAAMAKDKANMQHRYVELFLNSTAGTSGGAYDHSYVELFLNSTAGASGGAYGSQMMGGMGLSNQSSYGGPASQQLSGGYGG-----------------------------------GYGGQSSMSGYDQVLQE--------------------------------NSSDYQSNLA----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QFJ8-1", "uniprot_id": "F1QFJ8_DANRE", "id": "F1QFJ8-1", "name": "", "aln": "------------------------------------------MADDEGFVVRVRGLPWSCSAEEVSRFFSGCKISSNGSAIHFTYTRE-GRPSGEAFVELESEDDLKIAVKKDRESMGHRYVEVFKSNNVEMDWVLKHTGPNCPETEGDGLVRLRGLPFGCSKEEIVQFFSGLEIVPN--GITLPVDFQGRSTGEAFVQFASQDIAEKALKKHKERIGHRYIEIFKSSRAEVRTHYEPPRKGMGMQRPGPYDRPS-GGGRGYNGMSRGG-----------------SFDRMRRGGYGG-------------------------------GVSDGRYGDGGN-FQSTTGHCVHMRGLPYRATEPDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEDAVAAMSKDKANMQHRYVELFLN--------------------STAGGSNGGYGGQMMGGMG--NQSSYG-HGGQQMGGGYTG-----------------------------------GYSSQSSMGGYNDYNSQGG-----------------------------MSNSYYGGSRGSVGMNGMGGGWGM---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VGH5-1", "uniprot_id": "Q9VGH5_DROME", "id": "Q9VGH5-1", "name": "", "aln": "MSNADVQFNYGQQGNGDNFNDDSNQQQDEDDQYNEDGGGKIENVGESPKFVRLRGLPWSATHKEILDFLENVNVTNGSAGIHLVTSRVDGKNTGEAYVEVASQEDVEEARKLNKASMGHRYIEVFTATPKEAKEAMRKISGHG----TAFVVKLRGLPYAVTEQQIEEFFSGLDIKTDREGILFVMDRRGRATGEAFVQFESQDDTEQALGRNREKIGHRYIEIFRSSIAEMKRATGAGGG--VGGRPGPYDIRDRGANRGGNDFGGGRNDWGNNGNFGVGANNMLGFNNLPSLMNSGNFGNNQGGNNGNFGNNSGPSNFGNFGGGNNGGNSGNFGNDSGNSGNFGNFGNNGGGNFGGNNNGGGGFNSGNNFNSPGGVNNFGNNGGSNFGGNGGGGFNNGGNFVSSSGVGNFGPIGGGRNNNNGNFGNSGFGNFGGNNNVGSNFGGGNNGGGGGFNNGSNFGGGNSMGGGGNFGPIGGGRGNDIEYYTIHMRGLPYTSFENDVFKFFEPIRPANVRINYNKKGLHSGTADAYFDTYEDSQVAMKRHREQMGSRYIELFYDGKTRGLNGGEHGGGNGGGGMGNNGGGNFSRRI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . .*::******.: .*: *:.. :: .. :.::: :* *: :***:**: *::::: * * :: :*****:***.:. * . .::: . : .*:*****:. ::::* :*****:* .: *: : :* :**:******** **: :*:** :::*:*********:** **:: . ****** *..** *.:. * .*:.: .* * *. .*.*. : . .: . . . :* . :*. ::* :* . .: . ::.. . :.. .*: * . .*...*. *. *. .:* * :..* . .*. :. .* : : ... : .. . ", "identical_positions": 104, "similar_positions": 143, "identity": "17.57%" }, { "cls_id": "homologset.agr.MGI:1201780", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LXR0-1", "uniprot_id": "A0ABK0LXR0_RAT", "id": "A0ABK0LXR0-1", "name": "V-type proton ATPase catalytic subunit A", "aln": "-----------------------------------------------------------------------------------------MDFSKLPK---------------------------------IRDEDKESTFGYVHGVSGPVVTACDMAGAAMYELVRVGHSELVGEIIRLEGDMATIQVYEETSGVSVGDPVLRTGKPLSVELGPGIMGAIFDGIQRPLSDISSQTQSIYIPRGVNVSALSRDIKWEFIPSKNLRVGSHITGGDIYGIVNENSLIK-HKIMLPPRSRGSVTYIAPPGNYDASDVVLELEFEGVKEKLSMVQVWPVRQVRPVTEKLPANHPLLTGQRVLDALFPCVQGGTTAIPGAFGCGKTVISQSLSKYSNSDVIIYVG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CGERGNEMSEVLRDFPELTMEVDGKVESIMKRTALVANTSNMPVAAREASIYTGITLSEYFRDMGYHVSMMADSTSRWAEALREISGRLAEMPADSGYPAYLGARLASFYERAGRVKCLGNPEREGSVSIVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPSVNWLISYSKYMRALDEYYDKHFTEFVPLRTKAKEILQEEEDLAEIVQLVGKASLAETDKITLEVAKLIKDDFLQQNGYTPYDRFCPFYKTVGMLSNMISFYDMARRAVETTAQSDNKITWSIIREHMGEILYKLSSMKFKDPVKDGEAKIKADYAQLLEDMQNAFRSLED-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P50516-1", "uniprot_id": "VATA_MOUSE", "id": "P50516-1", "name": "V-type proton ATPase catalytic subunit A", "aln": "-----------------------------------------------------------------------------------------MDFSKLPK---------------------------------IRDEDKESTFGYVHGVSGPVVTACDMAGAAMYELVRVGHSELVGEIIRLEGDMATIQVYEETSGVSVGDPVLRTGKPLSVELGPGIMGAIFDGIQRPLSDISSQTQSIYIPRGVNVSALSRDIKWEFIPSKNLRVGSHITGGDIYGIVNENSLIK-HKIMLPPRNRGSVTYIAPPGNYDASDVVLELEFEGVKEKFSMVQVWPVRQVRPVTEKLPANHPLLTGQRVLDALFPCVQGGTTAIPGAFGCGKTVISQSLSKYSNSDVIIYVG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CGERGNEMSEVLRDFPELTMEVDGKVESIMKRTALVANTSNMPVAAREASIYTGITLSEYFRDMGYHVSMMADSTSRWAEALREISGRLAEMPADSGYPAYLGARLASFYERAGRVKCLGNPEREGSVSIVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPSVNWLISYSKYMRALDEYYDKHFTEFVPLRTKAKEILQEEEDLAEIVQLVGKASLAETDKITLEVAKLIKDDFLQQNGYTPYDRFCPFYKTVGMLSNMISFYDMARRAVETTAQSDNKITWSIIREHMGEILYKLSSMKFKDPVKDGEAKIKADYAQLLEDMQNAFRSLED-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P38606-1", "uniprot_id": "VATA_HUMAN", "id": "P38606-1", "name": "V-type proton ATPase catalytic subunit A", "aln": "-----------------------------------------------------------------------------------------MDFSKLPK---------------------------------ILDEDKESTFGYVHGVSGPVVTACDMAGAAMYELVRVGHSELVGEIIRLEGDMATIQVYEETSGVSVGDPVLRTGKPLSVELGPGIMGAIFDGIQRPLSDISSQTQSIYIPRGVNVSALSRDIKWDFTPCKNLRVGSHITGGDIYGIVSENSLIK-HKIMLPPRNRGTVTYIAPPGNYDTSDVVLELEFEGVKEKFTMVQVWPVRQVRPVTEKLPANHPLLTGQRVLDALFPCVQGGTTAIPGAFGCGKTVISQSLSKYSNSDVIIYVG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CGERGNEMSEVLRDFPELTMEVDGKVESIMKRTALVANTSNMPVAAREASIYTGITLSEYFRDMGYHVSMMADSTSRWAEALREISGRLAEMPADSGYPAYLGARLASFYERAGRVKCLGNPEREGSVSIVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPSVNWLISYSKYMRALDEYYDKHFTEFVPLRTKAKEILQEEEDLAEIVQLVGKASLAETDKITLEVAKLIKDDFLQQNGYTPYDRFCPFYKTVGMLSNMIAFYDMARRAVETTAQSDNKITWSIIREHMGDILYKLSSMKFKDPLKDGEAKIKSDYAQLLEDMQNAFRSLED-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FCD8-1", "uniprot_id": "E7FCD8_DANRE", "id": "E7FCD8-1", "name": "H(+)-transporting two-sector ATPase", "aln": "-----------------------------------------------------------------------------------------MDFSKLAK---------------------------------IRDEEREGQFGYVHGVSGPVVTASSMAGAAMYELVRVGHSELVGEIIRLEGDMATIQVYEETSGVSVGDPVLRTGKPLSVELGPGIMGSIFDGIQRPLKDINDLTQSIYIPRGVNIGALNRDLKWEFTPSKNLRVGSHITGGDIYGNVFENSLIK-HKIMLPPKSRGTVTYVAPPGNYDVSDVVLELEFEGVKEKFTMMQVWPVRQVRPVTEKLPANHPLLTGQRVLDALFPCVQGGTTAIPGAFGCGKTVISQSLSKYSNSDVIIYVG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CGERGNEMSEVLRDFPELTMEVGGKVESIMKRTALVANTSNMPVAAREASIYTGITLSEYFRDMGYNVSMMADSTSRWAEALREISGRLAEMPADSGYPAYLGARLASFYERAGRVKCLGNPEREGSVSIVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPSVNWLISYSKYTRALDEYYDKHFPEFVPLRTKAKEILQEEEDLAEIVQLVGKASLAETDKITLEVAKLIKDDFLQQNGYTPYDRFCPFYKTVGVLSNMIAFYDMARHAVETTAQSDNKITWAMIREHMGEILYRISSMKFKDPVKEGEEKIKADYAQLLEDMQNAFRTLED-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q27331-1", "uniprot_id": "VATA2_DROME", "id": "Q27331-1", "name": "V-type proton ATPase catalytic subunit A isoform 2", "aln": "-------------------------------------------------------------------------------------------MSNLKR---------------------------------FDDEERESKYGRVFAVSGPVVTAEAMSGSAMYELVRVGYYELVGEIIRLEGDMATIQVYEETSGVTVGDPVLRTGKPLSVELGPGIMGSIFDGIQRPLKDINELTESIYIPKGVNVPSLSRVASWEFNPLN-VKVGSHITGGDLYGLVHENTLVK-HKMIVNPRAKGTVRYIAPSGNYKVDDVVLETEFDGEITKHTMLQVWPVRQPRPVTEKLPANHPLLTGQRVLDSLFPCVQGGTTAIPGAFGCGKTVISQALSKYSNSDVIIYVG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CGERGNEMSEVLRDFPELSVEIDGVTESIMKRTALVANTSNMPVAAREASIYTGITLSEYFRDMGYNVSMMADSTSRWAEALREISGRLAEMPADSGYPAYLGARLASFYERAGRVKCLGNPEREGSVSIVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPSINWLISYSKYMRALDDFYDKNFPEFVPLRTKVKEILQEEEDLSEIVQLVGKASLAETDKITLEVAKLLKDDFLQQNSYSSYDRFCPFYKTVGMLRNIIDFYDMARHSVESTAQSENKITWNVIREAMGNIMYQLSSMKFKDPVKDGEAKIKADFEQLHEDLQQAFRNLED-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P48602-1", "uniprot_id": "VATA1_DROME", "id": "P48602-1", "name": "V-type proton ATPase catalytic subunit A isoform 1", "aln": "-------------------------------------------------------------------------------------------MSNLRK---------------------------------FKDEERESEYGRVYAVSGPVVTAEAMSGSAMYELVRVGYYELVGEIIRLEGDMATIQVYEETSGVTVGDPVLRTGKPLSVELGPGIMGSIFDGIQRPLRDIGVMTNSIYIPKGVNTTALSRSEMWEFNPLN-VRVGSHITGGDLYGVVHENTLVK-QRMIVAPRAKGTVRYIAPAGNYNLEDIVLETEFDGEITKHTMLQVWPVRQPRPVTEKLPANHPLFTGQRVLDSLFPCVQGGTTAIPGAFGCGKTVISQALSKYSNSDVIIYVG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CGERGNEMSEVLRDFPELTCEIDGVTESIMKRTALVANTSNMPVAAREASIYTGITLSEYFRDMGYNVAMMADSTSRWAEALREISGRLAEMPADSGYPAYLGARLATFYERAGRVKCLGNPEREGSVSIVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPSINWLISYSKYMRALDEYYDKNYPEFVPLRTKVKEILQEEEDLSEIVQLVGKASLAETDKVTLEVAKLLKDDFLQQNSYSPYDRVCPFYKTVGMLRNIMAFYETARHAVESTAQSDNKITWNTIRESMGGIMYQLSSMKFKDPVKDGEQKIKADYDQLYEDLQQAFRNLED-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VK47-1", "uniprot_id": "Q9VK47_DROME", "id": "Q9VK47-1", "name": "H(+)-transporting two-sector ATPase", "aln": "MEKKSWVAPLTSFTNSNASNEDRARNSGSLNQDGEPRSVPHPTVPAKKCTCPTCACQRNDHKSNPVPPPPQSRKPVAEPESPHDTVNDEDSLKDLRRSTDQSHKSAHIALEKNEDSGFVIEQVVDTHKYSSDEEEEEATMGRIFGVSGPVVNAEEMAGAAMYELVRVGHSQLVGEIIRLEGDMATIQVYEDTSGVSVGDPVYQTGKPLSVELGPGIMGSIFDGIQRPLRSISELTNSIYVPKGIDTPSLPRNIAYEFTPGK-LKIDALITGGDIYGSVFENSMMHDHRLILPPRTKGRIRWLAPPGNYCVDEVIVETEFNDEITKHTMLQVWPVRRCRPVEDKLPSNSPLLTGQRVLDAFFPCVQGGTTAIPGAFGCGKTVISQALSKYSNSDVIIYVG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CGERGNEMSEVLRDFPQLEVEVNGTMESIMKRTALVANTSNMPVAAREASIYTGITLSEYFRDMGYHVSMMADSTSRWAEALREISGRLAEMPADAGYPAYLGARLASFYERAGLVKCLGSPDREGSVSIVGAVSPPGGDFSDPVTSATLSIVQVFWGLDKKLAQRKHFPSVNWLQSYSKYMRTLDTYYEESNPEFTHLRAKAKKVLQEEDDLAEIVQLVGKSSLNEEDKITLEVAKMLKDDFLQQNSYSQYDAYCPFFKTIGMLKNMMTFYDAAILSVQNTADNEARVTWGLIRIKAANILYELSTMKFIDP-KLGEATVLESMNKLHDNILSTFREIEDNVEDY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P17255-1", "uniprot_id": "VATA_YEAST", "id": "P17255-1", "name": "V-type proton ATPase catalytic subunit A", "aln": "-----------------------------------------------------------------------------------MAGAIENARKEIKR--------------------------------ISLEDHAESEYGAIYSVSGPVVIAENMIGCAMYELVKVGHDNLVGEVIRIDGDKATIQVYEETAGLTVGDPVLRTGKPLSVELGPGLMETIYDGIQRPLKAIKEESQSIYIPRGIDTPALDRTIKWQFTPGK-FQVGDHISGGDIYGSVFENSLISSHKILLPPRSRGTITWIAPAGEYTLDEKILEVEFDGKKSDFTLYHTWPVRVPRPVTEKLSADYPLLTGQRVLDALFPCVQGGTTCIPGAFGCGKTVISQSLSKYSNSDAIIYVGCFAKGTNVLMADGSIECIENIEVGNKVMGKDGRPREVIKLPRGRETMYSVVQKSQHRAHKSDSSREVPELLKFTCNATHELVVRTPRSVRRLSRTIKGVEYFEVITFEMGQKKAPDGRIVELVKEVSKSYPISEGPERANELVESYRKASNKAYFEWTIEARDLSLLGSHVRKATYQTYAPILYENDHFFDYMQKSKFHLTIEGPKVLAYLLGLWIGDGLSDRATFSVDSRDTSLMERVTEYAEKLNLCAEYKDRKEPQVAKTVNLYSKVVRGNGIRNNLNTENPLWDAIVGLGFLKDGVKNIPSFLSTDNIGTRETFLAGLIDSDGYVTDEHGIKATIKTIHTSVRDGLVSLARSLGLVVSVNAEPAKVDMNGTKHKISYAIYMSGGDVLLNVLSKCAGSKKFRPAPAAAFARECRGFYFELQELKEDDYYGITLSDDSDHQFLLANQVVVHNCGERGNEMAEVLMEFPELYTEMSGTKEPIMKRTTLVANTSNMPVAAREASIYTGITLAEYFRDQGKNVSMIADSSSRWAEALREISGRLGEMPADQGFPAYLGAKLASFYERAGKAVALGSPDRTGSVSIVAAVSPAGGDFSDPVTTATLGITQVFWGLDKKLAQRKHFPSINTSVSYSKYTNVLNKFYDSNYPEFPVLRDRMKEILSNAEELEQVVQLVGKSALSDSDKITLDVATLIKEDFLQQNGYSTYDAFCPIWKTFDMMRAFISYHDEAQKAVANGAN------WSKLADSTGDVKHAVSSSKFFEP-SRGEKEVHGEFEKLLSTMQERFAESTD-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ..: : ::. *. * :..****** * * *.******:**: :****:**::** *******:*:*::***** :************:* :*:******* * ::***:*:*:: :* * ::* * : .::. *:***:** * **::: ::::: *: :* : ::**.*:* .: ::* **:. . :: :.**** *** :**.:: **:*******::*********.**************:********.***** ********:*** :**:* *:.* *.*****:***********************:***** * :*:*:***:**************.***** *:******:**:****** . .**.*:* ******.****.*********:***.*.******************:* ***** ..*: :*:. .** ** : *::*.: ::* ::******::* : **:**:**.::*:******.*: ** **::**..:: :: ::: * :* . *: * : . : : :*: ** :* . ** : . :* . : . * * ", "identical_positions": 334, "similar_positions": 159, "identity": "27.86%" }, { "cls_id": "homologset.agr.MGI:1201781", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3Z8F1-1", "uniprot_id": "D3Z8F1_RAT", "id": "D3Z8F1-1", "name": "", "aln": "-------------------------------------------------------------MDSNQVLPAINSHRALQIWITENLKMLPLPEKAHGNFFEECCYVVLHSP---KATQGGSRD------------LHCWIGKEASTEAQEAAVSFMHRLQQDLGDQTVLHRESQGHESDCFHSYFRPGVIYRKGGRASALKLGESNVYNVQRLLHIRGRKHVSATEVA-LSWNSFNKGDIFLLDLGKVMIQWNGPKASICEKARALSLTCSLRDRERGG-RAQIRVVD---AENKATDLMSIMEAVLGRRSGSLCASVPSNSVSQLQKAN-IRLYHVFEKGTDLVVQELATRPLTQDLLQEDGCYLLDQGGFKIYMWQGRKSSPEERKAAFSRAVGFIQAKGYPNYTNVEVVNDGAESTAFQQLFWTWSKE-----LNGKKHPRQSKLMQQVNLEVGKLHTQPELAAQLRMVDDGSGKVEVWYIQGSQRQPVDPKHHGQLCSGNCYLVLYKYQKLGRV---------QYILYLWQGHQSTVEDVKALNCNAEELDLLHQGALVQGHVTMGREPPHFLAIFQGQLVVLQGN---AGNKGGRLPISDTRLFHVQGTESHNTRTMEVPARASSLTSSDVFFLITSHVCYLWFGKGCHGDQREMARTVVTVFPGNNKETVLEGQEPLHFWEALGG-------------------------------------RAPYPSNKRLPEEISSIQPR----LFECSSHSGHLVLTEVVFFGQEDLDKYDIMLLDTCQEIFLWLGEAAGEWKK-AAVAWGHEYLRTHPAERSLATPIIVVKQGREPATFTGWFVTWDPYKWTSSQSYEEMVEGSLGPGSAISEITAEVHNFQLTARPSDSEAGRPTLLAFKGSQDSPENELELGLRVDGETPSMNHTSSCSSSMINGSLPRERLMHQALEDLPQGVDPARKEVGTRPN-----------------CWKTPRDPAP----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91YD6-1", "uniprot_id": "VILL_MOUSE", "id": "Q91YD6-1", "name": "Villin-like protein", "aln": "-------------------------------------------------------------MDINQDLPAIDSHRALQIWITENLKMLPLPERAHGNFFEECCYVVLHVPQSPKATQGGSSD------------LHYWIGKDASAEAREAAVSFVQCLQEDLGDQTVLHRESQGHESDCFHSYFHPGVIYRKGGRDSALKFAETNMYNVQRLLHIKGRKHVSATEVA-LSWNSFNKGDIFLLDLGKVMIQWNGPKASISEKARALTLTCNLRDRERGG-RAQIAVVD---AENEATNLLRIMEAVLGCRSGSLCPSVPSNSVSQLQKAN-VRLYHVCEKGTDLVVQELATRPLTQDLLQEDGCYLLDQGGFKIYMWQGRKSSPQEKKAALSRAVGFIQAKGYPNYTNVEVVNDGAESTAFQQLFWSWSKE-----LDRKKHPEKSKLVQG-NLEVGKLHTQPELAAQLRMVDDGSGKVEVWYIQDLQRQPVHPKYYGQLCSGNCYLVLYTYQKLGCV---------QYLLYLWQGHQSTVEDTKALNCSAEELDLMHQGALAQGHVTMGSEPPHFLAIFQGRLVVFQGN---AGNKGERPPVSDTRLFHVQGTESHNTRTMEVPARASSLTSGDVFFLITSHVCYLWFGKGCHGDQREMARTVVSVFPGNNKETVLEGQEPLYFWEALGG-------------------------------------RAPYPSNKRLPEEVWSIQPR----LFECSSHAGCLVLTEVLFFGQEDLDKYDIMLLDTCQEIFLWLGEAAGEWKK-EAVAWGLEYLRTHPAERSLATPIFVVKQGHEPATFTGWFVTWDPYKWMNSQSYEEMVGNSLGPGSAISEMTAEVHNFQLTPRLSDNKAGHPALQAFKGSQDSPENELGLDLRVDGANPSMNHTSSCSDSMVNGSLPRERLMHQALEDLPPGVDPARKEFYLSDSDFQDIFGKSKEEFYSMAKWKQQQAKKKLGFF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15195-1", "uniprot_id": "VILL_HUMAN", "id": "O15195-1", "name": "Villin-like protein", "aln": "-------------------------------------------------------------MDISKGLPGMQGG--LHIWISENRKMVPVPEGAYGNFFEEHCYVILHVPQSPKATQGASSD------------LHYWVGKQAGAEAQGAAEAFQQRLQDELGGQTVLHREAQGHESDCFCSYFRPGIIYRKGGLASDLKHVETNLFNIQRLLHIKGRKHVSATEVE-LSWNSFNKGDIFLLDLGKMMIQWNGPKTSISEKARGLALTYSLRDRERGGGRAQIGVVD---DEAKAPDLMQIMEAVLGRRVGSLRAATPSKDINQLQKAN-VRLYHVYEKGKDLVVLELATPPLTQDLLQEEDFYILDQGGFKIYVWQGRMSSLQERKAAFSRAVGFIQAKGYPTYTNVEVVNDGAESAAFKQLFRTWSEK-----RRRNQKLGGRDKSIHVKLDVGKLHTQPKLAAQLRMVDDGSGKVEVWCIQDLHRQPVDPKRHGQLCAGNCYLVLYTYQRLGRV---------QYILYLWQGHQATADEIEALNSNAEELDVMYGGVLVQEHVTMGSEPPHFLAIFQGQLVIFQER---AGHHGKGQSASTTRLFQVQGTDSHNTRTMEVPARASSLNSSDIFLLVTASVCYLWFGKGCNGDQREMARVVVTVISRKNEETVLEGQEPPHFWEALGG-------------------------------------RAPYPSNKRLPEEVPSFQPR----LFECSSHMGCLVLAEVGFFSQEDLDKYDIMLLDTWQEIFLWLGEAASEWK--EAVAWGQEYLKTHPAGRSPATPIVLVKQGHEPPTFIGWFFTWDPYKWTSHPSHKEVVDGSPAAASTISEITAEVNNLRLSRWPGNGRAGAVALQALKGSQDSSENDLVRSPKSAGSRTSS--SVSSTSATINGGLRREQLMHQAVEDLPEGVDPARREFYLSDSDFQDIFGKSKEEFYSMATWRQRQEKKQLGFF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9P642-1", "uniprot_id": "A0A8M9P642_DANRE", "id": "A0A8M9P642-1", "name": "", "aln": "MEIYIGISAKLLCLLTLAAEKGLDSKSLSLISTKRKTQFIHTVQHQPQQHLCLTHTEFSRMTEAHDLFKNIQRKPGLQIWTINKMQMVAVPEQAFGNFFEGDCYIILNVS----NNPAQSID------------IHYWIGNSSSQDEQGAAAIYVTQLDENFGGSPVQYREVQGHESVKFKSYFKNGLIYKKGGVASGFTHVETNVYNIQRLLHVKGTKHVTGREVE-VSWNSFNLGDVFLLDLGKAIIQWNGPQSNRQEKLKAVMLAQDIRDRERGG-RAQIGVIEG-AQEEASPELMKVMVSVLGQRIGQMKEAIPDDKPGQNQISN-VKLYQVSDASGQLLVQEVAVSPLTQDLLCSSDCYILDQGGTSIMVWKGKGASNEERRSAMGRAVGFIKAKNYPASTKVEVMSEGGESAMFKQLFKSWTEKGQTQGLGKTHSVGKIAKVDQVKFDVMELHAQPKLAAQERMVDDASGQVQVWRIENLELKEVDRSTYGQFYGGDCYLVLYTYNRANKP---------QYILYIWQGRHATQDEVTASAYQAVNLDNKYNGAPTQVRVVMGKEPRHFMAIFKGRLIIFEGG---TGRSGVVNPDPAARLFQVRGTHELNTKATEVPARASSLNTNDVFLLKTYQTVFLWYGKGCSGDEREMGKAVADLLSGQDKQTVMEGQEPAAFWVPLGG-------------------------------------KAPYASDKRLEEEVSLHEPR----LFECSNQTGRFLMTEVADFTQDDLDEDDVMLLDTWDEIFLWIGNSANQYEIQESSSSAVEYLKTHPAGRDAGTPITTVKQGYEPPTFTGWFNAWDAHKWSGGLSYEEMKS-KLG---DVSQITVSLNNTDLNKKPGGG-VGNYSAPGGPGSIRSHNQRMSSVQFGDGS----------QNRAKPSGMQNSEQLVKMPNQLPQGLDPEKREEYLSDAEFENLLGCTRANFQRLPKWRQNDLKKKAGLF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q23989-1", "uniprot_id": "QUAI_DROME", "id": "Q23989-1", "name": "Villin-like protein quail", "aln": "-----------------------------------------MELSLSPKETEIRPNTIPDLKVDATFRKVAKHAITFAIWKIDEDRLEAVQRSHYGTFYDSCAYIIYAASLSGHYANHETITREQKPNVSLERYIHYWLGKNVSEQNRSNVVHKIQELDSYLGNISSIYRETQNLESARFLSYFKKGYDVRSGALISAPQR--------PRLFQLYARKWLRSIEVATIDWSHFNSDYVMVLQTDNLTYVWIGRSSSGIERRSALDWVQKHCSG------SPITIVDDGYEQAMSQEHKELWNTMLPLKKRMVCQASQLVSEYADYNSNKFRIYKCNQRGRLHLDQLDVGMPAKDDLSDAHGVYLLDNYGQSIWLWVGGQAPQADALSAMGNGRAFVKKKKYPDNTLVVRVLEGHEPVEFKRLFANWLNV-----WQENTRGHKPVSTKFGKLDAHSLCERPKMAADTQLVDDGRGERVIYRVFGDQVQEVPISKTVVFTTNASFVVKYSVQCATVVPADLASVGIKTIIYQWNGSEASVESISRADKFAKASFDGLKEPGMFVQLYEFDEPPHFLQIFEGKLIIRRGQRTEMPYNGNSNALLDTFLLKVYGDASYNAKAVEETH-LSSISSKDCYVIKTN-HVWVWCGQSSTGDAREMAKAVGALMGENS--LVLEGKESKEFWQSVAMYFNQTLVINGNGNSCSSSTSSSSGAGSMCNGSSNGGNISPTLSNNCYLNTSVPSKPRPPVQLFLVWWQQSSLRYEEILGFDQQDLSSDCTYILDTGSLTYVWLGSQAPNQER--YTAIAQSYVQNAPFGRRSATALAVVRQFQEPNVFKGFFESWQNDYGKNFHSYEKMRKDLGNKVTSNCCFASEGSALILNNR----------QKDFDGHKKYP----------------------------------LTVLIQEMDMLPPDINPLKREVHLTHDDFVSVFNMSFYEFDELPKWKKMELKKQFKLF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : ** :: :: .: . .*.*:: .*:: . : :* *:*:. . : : . *:. :*. . :** *. ** * ***: * :.*. * **::: . * : . ** :.*. ** . :::*: .: * * .:. *: .: . . . : * ::: : : : : ::* : : : . :* .::*: : . : . * .:** . *:**: * .* :* * :. : :*:... .*:: * ** * * : :* *.. *::** .* : . :::. .* :*::**: ::***. *: :: : . . : * . : . .::* *. : : ::* *:* .:: :. * :: ** **: **:*:*:: . * . : *::* * . *::: * . **:.: * :.: * ::* *:.. ** ***.:.* :: :. *:**:*. ** .:. :* *:: : :** ** : . : *: * *:**.. :*** . ::*:*. * : : : . .*::. * * .*.: *:* ** .* *:* :*: . *:::: . :: . *. * : : : ** .::* ::* *: ", "identical_positions": 145, "similar_positions": 242, "identity": "14.53%" }, { "cls_id": "homologset.agr.MGI:1201782", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6V0K7-1", "uniprot_id": "OIT3_RAT", "id": "Q6V0K7-1", "name": "Oncoprotein-induced transcript 3 protein", "aln": "-------------MPLSLLLACLFTTVTLQSPVVLDPCSAYISLNEPWRNTDHQFDESQSQPLCDNHMDGEWYRFTGMAGDAMPTFCIPENHCGTHAPVWLNGSHPLEGDGIVQRQACASFKGNCCLWNTTVEVKACPGGYYVYRLAKPSVCFHIYCGHFYDICDE-DCHGS-CLDTTECACSPGTSLGPDGQTCFDENECEHNNGGCSEICVNLKNSHRCACGVGRVLRSDGKTCEDIEGCHSNNGGCSHSCLGSEKGYQCECPRGLVLSEDNHTCQVPVLCKSSAIEVSVPRELVGGLELFLTNTSCRGVSNGTHVNIIFSLKTCGTVVDVVNDKIVASNLVTGLPKQTPGSSGDIIIRTSKLLIPVTCEFPRLYTISEGYVPNLRNAPLEIRSRNHGIFPFTLEIFKDHEFEEPYRETLPTLKLRDSLYFGIEPLVHVSGLESLVESCFATPTAKVDEILKYYLIRDGCVSDDSVKQYSSRDHLAKHFQVPVFKFVGKDHKEVFLHCRVLVCGVLDERSRCAQGCHRRVRREAGEDEDSAGLQSQTLTGGPISIDWEE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R4V5-1", "uniprot_id": "OIT3_MOUSE", "id": "Q8R4V5-1", "name": "Oncoprotein-induced transcript 3 protein", "aln": "-------------MPLSLLLTCLSTTVTLVSPAVLDPCSAYISLNEPWRNTDHQFDESQNQPLCDNHMNGEWYRFTGMAGDAMPTFCIPENHCGTHAPVWLNGSHPLEEDGIVQRQACASFKGNCCLWNATVEVKACPRGYYVYRLARPSVCFHVYCGHFYDICDE-DCHGN-CLDTTECACSPGTSLGPDGQTCFDENECEHNNGGCSEICVNLKNSHRCACGVGRVLRSDGKTCEDIEGCHNNNGGCSHSCLGSEEGYQCECPRGLVLSEDNHTCQVPVLCKSSAIEVSVPRELVGGLELFLTNTSCRGVSNGTHVNIVFSLKTCGTVVDVVNDKIVASNIVTGLPKETPGSSGDIIIRTSKLLIPVTCEFPRLYTISEGYVPNLRNAPLEIRSRNHGIFPFTLEIFKDHEFEEPYRETLPTLKLRDSLYFGIEPLVHVNGLESLVESCFATPTAKMDEILKYYLIQDGCVSDDSVKQYSSRDHLAKHFQAPVFKFVGKDHKEVFLHCRVLVCGVLDERSRCAQGCHRRVRREVGEDEDSAGLQSQTLTGGPIAIDWED", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WWZ8-1", "uniprot_id": "OIT3_HUMAN", "id": "Q8WWZ8-1", "name": "Oncoprotein-induced transcript 3 protein", "aln": "-------------MPPFLLLTCLFITGTSVSPVALDPCSAYISLNEPWRNTDHQLDESQGPPLCDNHVNGEWYHFTGMAGDAMPTFCIPENHCGTHAPVWLNGSHPLEGDGIVQRQACASFNGNCCLWNTTVEVKACPGGYYVYRLTKPSVCFHVYCGHFYDICDE-DCHGS-CSDTSECTCAPGTVLGPDRQTCFDENECEQNNGGCSEICVNLKNSYRCECGVGRVLRSDGKTCEDVEGCHNNNGGCSHSCLGSEKGYQCECPRGLVLSEDNHTCQVPVLCKSNAIEVNIPRELVGGLELFLTNTSCRGVSNGTHVNILFSLKTCGTVVDVVNDKIVASNLVTGLPKQTPGSSGDFIIRTSKLLIPVTCEFPRLYTISEGYVPNLRNSPLEIMSRNHGIFPFTLEIFKDNEFEEPYREALPTLKLRDSLYFGIEPVVHVSGLESLVESCFATPTSKIDEVLKYYLIRDGCVSDDSVKQYTSRDHLAKHFQVPVFKFVGKDHKEVFLHCRVLVCGVLDERSRCAQGCHRRMRRGAG-GEDSAGLQGQTLTGGPIRIDWED", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RNR8-1", "uniprot_id": "A0A8M1RNR8_DANRE", "id": "A0A8M1RNR8-1", "name": "", "aln": "MYICDFRVLLYLQLDMLFTLFVVLQAVSDTQAIALDPCSAYISLNEPWRNTDYHVNNSAGVPLCDRHVSGEWYRFTGMAGDAMPTFCIQENHCGTHAPIWLNGSHPGPSDGVVTLSACASFNNNCCHWTASVEIKACPRGYYVYRLPRPSVCFHVYCGHFYDICDEIECTGSDCPVEPECRCSEGTILGPDAQTCLDVNECEKGNGGCAELCINTKGSRRCECGPGKVLDVDGKSCKETAGCDNVNGGCSHGCSSDEDSYYCHCPWGLMLGDDKRTCQVPVQCDPSSIEVSVPKDLVGGLELFLSNTSCRGISNGTHINIHFSLKTCGTVIQVSDDKIIGTNLVTGLPRSSPSSNGDLIVRTSKLLLPITCEFPRQYEVSDGYLPSLRNTALELAGHSEGIFPFSLELFKSAEFSEPYNQ-PPQLKLRDVLYFGVEPRERVDGLTAFVENCFATPGPKADQALKYYLIKDGCISDETVRQLSAKDELSKHYQVPVFKFIGKDNREVFLHCRVLVCGQTQGESRCTQGCRKRLRRDVWTDQHQE---QNILSSGPIHILPDP", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : * : : : .. .******************::.::* . ****.*:.****:************** *********:******* **:* .*****:.*** *.::**:**** *******.:******:*********** :* *. * .** *: ** **** ***:* ****:.****:*:*:* *.* ** ** *:** ***:*:: **.. ******.* ..*..* *.** **:*.:*::****** *...:***.:*::*********:******:*****:** *********::* :***:.:*:*****:.:*.*.**:*:******:*:****** * :*:**:*.***:.**: .:..*****:**:**. **.***.: * ***** ****:** :*.** ::**.***** .* *: ******:***:**::*:* :::*.*:**:*.*****:***::************ : .***:***::*:** . .:.. : *:.*** * : ", "identical_positions": 329, "similar_positions": 140, "identity": "58.65%" }, { "cls_id": "homologset.agr.MGI:1201784", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97805-1", "uniprot_id": "FAM3D_MOUSE", "id": "P97805-1", "name": "Protein FAM3D", "aln": "----------------------MRVAGLIRVVVFIFT------IVTMWVFLRSYTSFSRKTIRLPR---------WLGITP-KDIQTPKSKCGLSKICP--------NNFFAFKIS-SGAANVVGP--------------------SMCFEDEIIMSPVRNNVGRGLNVALVNGSTGQVMKKDSFDMYSGDPQLLLNFLTEIPDSTLVLVASYDDPGTKMNDKIKTLFSNLGSSYAKQLGFRDSWVFVGAKDLKSKSPYEQFLKNNPETNKYDGWPELLELEGCVPRKVM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96BQ1-1", "uniprot_id": "FAM3D_HUMAN", "id": "Q96BQ1-1", "name": "Protein FAM3D", "aln": "----------------------MRVSGVLRLLALIFA------IVTTWMFIRSYMSFSMKTIRLPR---------WLAASPTKEIQVKKYKCGLIKPCP--------ANYFAFKIC-SGAANVVGP--------------------TMCFEDRMIMSPVKNNVGRGLNIALVNGTTGAVLGQKAFDMYSGDVMHLVKFLKEIPGGALVLVASYDDPGTKMNDESRKLFSDLGSSYAKQLGFRDSWVFIGAKDLRGKSPFEQFLKNSPDTNKYEGWPELLEMEGCMPPKPF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0M8X9-1", "uniprot_id": "A0ABK0M8X9_RAT", "id": "A0ABK0M8X9-1", "name": "", "aln": "MGLLCGWGRRPQLRHISTALHIPRARGILRVYLVAALGPSPGLIPIAKQLPQKPQPESRNVLRGPEEWQSTACGCWWAVANPAELHTHSWLAMAHRTRPPCLAFGSQSHCLCFLVLLSWAPEVEGPLKVPNTEAQLSFCGWDHQPSSLSFSIRSIMSPVRNNVGRGLNIALVNGTTGRVIRKASFDMYSGEPQPLLDFLTEIPDSTLVLVASYDDPGTKMNDKIKTLFTNLGSSYAKQLGFRDSWVFVGAKDLRSKSPYEQFLKNNPETNKYEGWPELLELEGCVPKKVM", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. *::*: . * : :. . * :.:* *. * . : :::. . . : * : :.* : * *.:* ** ::.*. . *****:********:*****:** *: : :******: *:.**.***..:****************: :.**::*****************:*****:.***:******.*:****:*******:***:* * :", "identical_positions": 115, "similar_positions": 61, "identity": "39.66%" }, { "cls_id": "homologset.agr.MGI:1201785", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97808-1", "uniprot_id": "FXYD5_MOUSE", "id": "P97808-1", "name": "FXYD domain-containing ion transport regulator 5", "aln": "MSLSSRLCLLTIVALILPSRGQTPKKPTSIFTADQTSATTRDNVPDPDQTSPGVQTTPLI--WTRE--EATGSQTAAQTETQQLTKMATSNPVSDPGPHTSSKKGTP---AVSRIEPLSPSKNFMPPSYIEHPLDSNENNPFYYDDTTLRKRGLLVAAVLFITGIIILTSGKCRQLSQFCLNRHR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P59647-1", "uniprot_id": "FXYD5_RAT", "id": "P59647-1", "name": "FXYD domain-containing ion transport regulator 5", "aln": "MSPPSQLCLLTIVALILPSEGQTPEKPRSSFTAHQSSVTT--HVPVPDQTSPGVQTTPPI--WTSEAGEATGSQTAAKTKTQQLTEMATANPVTDPGPLTSSEKGTP---ALSRIKSPSPPKGYMPPSYIENPLDPNENSPFYYDNTTLRKRGLLVAAVLFITGIIILTSGKCRQFSQLCLNRHR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96DB9-1", "uniprot_id": "FXYD5_HUMAN", "id": "Q96DB9-1", "name": "FXYD domain-containing ion transport regulator 5", "aln": "MSPSGRLCLLTIVGLILPTRGQTLKDTTSSSSADSTIMDIQVPTRAPDAVYTELQPTSPTPTWP------ADETPQPQTQTQQLEGTDGP-LVTDPETHKSTKAAHPTDDTTTLSERPSPSTDVQTDPQTLKPSGFHEDDPFFYDEHTLRKRGLLVAAVLFITGIIILTSGKCRQLSRLCRNRCR", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** ..:*******.****:.*** :.. * :*..: . ** . . :*.*. *. :.. . .:*:**** . *:** . .*:: . * : : : **... . . :* . :*:.**:**: ****************************:*::* ** *", "identical_positions": 74, "similar_positions": 52, "identity": "40.0%" }, { "cls_id": "homologset.agr.MGI:1201787", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88582-1", "uniprot_id": "SOCS2_RAT", "id": "O88582-1", "name": "Suppressor of cytokine signaling 2", "aln": "MTLRCLEPSGNGADRTRSQWGTAGSPEDQSPEAARLAKALRELSQTG-WYWGSMTVNEAKEKLKEAPEGTFLIRDSSHSDYLLTISVKTSAGPTNLRIEYQDGKFRLDSIICVKSKLKQFDSVVHLIDYYVQMCKD--K-RTGPEAPRNGTVHLYLTKPLYTSAPTLQHFCRLSINKCTGTIRGLPLPTRLKDYLEEYKFQV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35717-1", "uniprot_id": "SOCS2_MOUSE", "id": "O35717-1", "name": "Suppressor of cytokine signaling 2", "aln": "MTLRCLEPSGNGADRTRSQWGTAGLPEEQSPEAARLAKALRELSQTG-WYWGSMTVNEAKEKLKEAPEGTFLIRDSSHSDYLLTISVKTSAGPTNLRIEYQDGKFRLDSIICVKSKLKQFDSVVHLIDYYVQMCKD--K-RTGPEAPRNGTVHLYLTKPLYTSAPTLQHFCRLAINKCTGTIWGLPLPTRLKDYLEEYKFQV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14508-1", "uniprot_id": "SOCS2_HUMAN", "id": "O14508-1", "name": "Suppressor of cytokine signaling 2", "aln": "MTLRCLEPSGNGGEGTRSQWGTAGSAEEPSPQAARLAKALRELGQTG-WYWGSMTVNEAKEKLKEAPEGTFLIRDSSHSDYLLTISVKTSAGPTNLRIEYQDGKFRLDSIICVKSKLKQFDSVVHLIDYYVQMCKD--K-RTGPEAPRNGTVHLYLTKPLYTSAPSLQHLCRLTINKCTGAIWGLPLPTRLKDYLEEYKFQV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3ARE8-1", "uniprot_id": "A0A8M3ARE8_DANRE", "id": "A0A8M3ARE8-1", "name": "Suppressor of cytokine signaling 2", "aln": "MTCHSSDSTESIENERRSQSETQVADTEQS----RIATAMRDLKNTAGWYWGSLTANEAKEILQDTSEGTFLVRDSSQRDYLFTISAMTSAGPTNLRIEYKDGKFKLDSVVLVKPKLKQFDSVVHLVEHYVQLSRTSCKGRTNQIAPSNGTVQLLLTTPVYTATPSLQHLCRIAINKTTRRVQELPLPNRLKDYLTDYTYNV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** :. :.: . : *** * : * *:*.*:*:* :*. *****:*.***** *:::.*****:****: ***:***. ************:****:***:: **.***********:::***:.: * **. ** ****:* **.*:**::*:***:**::*** * : ****.****** :*.::*", "identical_positions": 112, "similar_positions": 51, "identity": "55.45%" }, { "cls_id": "homologset.agr.MGI:1201789", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P83883-1", "uniprot_id": "RL36A_RAT", "id": "P83883-1", "name": "Large ribosomal subunit protein eL42", "aln": "MVNVPKTRRTFCK--KCGKHQPHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQTKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKGQVIQF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P83882-1", "uniprot_id": "RL36A_MOUSE", "id": "P83882-1", "name": "Large ribosomal subunit protein eL42", "aln": "MVNVPKTRRTFCK--KCGKHQPHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQTKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKGQVIQF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P83881-1", "uniprot_id": "RL36A_HUMAN", "id": "P83881-1", "name": "Large ribosomal subunit protein eL42", "aln": "MVNVPKTRRTFCK--KCGKHQPHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQTKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKGQVIQF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P61485-1", "uniprot_id": "RL36A_DANRE", "id": "P61485-1", "name": "Large ribosomal subunit protein eL42", "aln": "MVNVPKTRRTYCK--KCKKHQPHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQTKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKGQVIQF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VLT7-1", "uniprot_id": "Q9VLT7_DROME", "id": "Q9VLT7-1", "name": "", "aln": "MVNVPKQRRTFCK--KCKVHKLHKVTQYKKSKERKGAQGRRRYDRKQQGFGGQTKPIFRKKAKTTKKIVLRMECTE--CKYRKQTPLKRCKHFELGGDKKRKGQMIQF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P0CX28-1", "uniprot_id": "RL44B_YEAST", "id": "P0CX28-1", "name": "Large ribosomal subunit protein eL42B", "aln": "MVNVPKTRKTYCKGKTCRKHTQHKVTQYKAGKASLFAQGKRRYDRKQSGFGGQTKPVFHKKAKTTKKVVLRLECVK--CKTRAQLTLKRCKHFELGGEKKQKGQALQF", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P0CX27-1", "uniprot_id": "RL44A_YEAST", "id": "P0CX27-1", "name": "Large ribosomal subunit protein eL42A", "aln": "MVNVPKTRKTYCKGKTCRKHTQHKVTQYKAGKASLFAQGKRRYDRKQSGFGGQTKPVFHKKAKTTKKVVLRLECVK--CKTRAQLTLKRCKHFELGGEKKQKGQALQF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****** *:*:** .* * ******* .* ***:*******.*:******:*:********:***:**.: *: : .:**********:**:*** :**", "identical_positions": 69, "similar_positions": 20, "identity": "63.89%" }, { "cls_id": "homologset.agr.MGI:1201791", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88583-1", "uniprot_id": "SOCS3_RAT", "id": "O88583-1", "name": "Suppressor of cytokine signaling 3", "aln": "MVTHSKFPAAGMSRPLDTSLRLKTFSSKSEYQLVVNAVRKLQESGFYWSAVTGGEANLLLSAEPAGTFLIRDSSDQRHFFTLSVETQSGTKNLRIQCEGGSFSLQSDPRSTQPVPRFDCVLKLVHHYMPPPGAPSFSLPPTEPSFEVQEQPPAQALPGGTPKRAYYIYSGGEKIPLVLSRPLSSNVATLQHLCRKTVNGHLDSYEKVTQLPGPIREFLDQYDAPL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35718-1", "uniprot_id": "SOCS3_MOUSE", "id": "O35718-1", "name": "Suppressor of cytokine signaling 3", "aln": "MVTHSKFPAAGMSRPLDTSLRLKTFSSKSEYQLVVNAVRKLQESGFYWSAVTGGEANLLLSAEPAGTFLIRDSSDQRHFFTLSVKTQSGTKNLRIQCEGGSFSLQSDPRSTQPVPRFDCVLKLVHHYMPPPGTPSFSLPPTEPSSEVPEQPPAQALPGSTPKRAYYIYSGGEKIPLVLSRPLSSNVATLQHLCRKTVNGHLDSYEKVTQLPGPIREFLDQYDAPL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14543-1", "uniprot_id": "SOCS3_HUMAN", "id": "O14543-1", "name": "Suppressor of cytokine signaling 3", "aln": "MVTHSKFPAAGMSRPLDTSLRLKTFSSKSEYQLVVNAVRKLQESGFYWSAVTGGEANLLLSAEPAGTFLIRDSSDQRHFFTLSVKTQSGTKNLRIQCEGGSFSLQSDPRSTQPVPRFDCVLKLVHHYMPPPGAPSFPSPPTEPSSEVPEQPSAQPLPGSPPRRAYYIYSGGEKIPLVLSRPLSSNVATLQHLCRKTVNGHLDSYEKVTQLPGPIREFLDQYDAPL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "************************************************************************************:***********************************************:***. ****** ** ***.**.***..*:***************************************************************", "identical_positions": 214, "similar_positions": 8, "identity": "95.11%" }, { "cls_id": "homologset.agr.MGI:1201792", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q61481-4", "uniprot_id": "PDE1A_MOUSE", "id": "Q61481-4", "name": "Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A", "aln": "----------------------------------------------------MGSTDTDIEELENATYKYLIGEQTEKM----------------WQRLKG------------------ILRCLVKQLEKGDVNVVDLKKNIEYAASVLEAVYIDETR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RLLDTEDELSDIQTDSVPSEVRDWLASTFTRKMGMMKKKPEEKPKFRSIVHAVQAGIFVERMYRKNYHMVGLTYPAAVIVTLKEVDKWSFDVFALNEAS----GEHSLKFMIYELFTRYDLINRFKIPVSCLIAFAEALEVGYSKHKNPYHNLVHAADVTQTVHYIMLHTGIMHWLTELEILAMVFAAAIHDYEHTGTTNNFHIQTRSDVAILYNDRSVLENHHVSAAYRLMQEEEMNILVNLSKDDWRDLRNLVIEMVLATDMSGHFQQIKNIRNSLQQPEG-IDRAKTMSLILHAADISHPAKTWKLHYRWTMALMEEFFLQGDKEAELGLPFSPLCDRKSTMVAQSQIGFIDFIVEPTFSLLTDSTEKIVIP-----------LIEEASKSQSSNYGASSSSTMIGFHVADSLRRSNTKGSVCDGSYAPDYSLSAVDLKSFKN--NLVDIIQQNKERWKELAAQGELDLHKN-----------SEELGNTEEKHADTRP-------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5Y792-1", "uniprot_id": "A0A8I5Y792_RAT", "id": "A0A8I5Y792-1", "name": "Phosphodiesterase", "aln": "-----------------------------MITASLDGHTLSITTCGALGNIIMGSTDTDIEELENATYKYLIGEQTEKM----------------WQRLKG------------------ILRCLVKQLEKGDVNVVDLKKNIEYAASVLEAVYIDETR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RLLDTEDELSDIQTDSVPSEVRDWLASTFTRKMGMTKKKPEEKPKFRSIVHAVQAGIFVERMYRKNYHMVGLTYPAAVIVTLKEVDKWSFDVFALNEAS----GEHSLKFMIYELFTRYDLINRFKIPVSCLIAFAEALEVGYSKHKNPYHNLVHAADVTQTVHYIMLHTGIMHWLTELEILAMVFAAAVHDYEHTGTTNNFHIQTRSDVAILYNDRSVLENHHVSAAYRLMQEEEMNILVNLSKDDWRDLRNLVIEMVLATDMSGHFQQIKNIRSSLQQPEG-IDRAKTMSLILHAADISHPAKTWKLHYRWTMALMEEFFLQGDKEAELGLPFSPLCDRKSTMVAQSQIGFIDFIVEPTFSLLTDSTEKIVIP-----------LIEEASKPESSNYGASSSSTMIGFHVADALRRSNTKGCMSDGTYAPDYSLSAVDLKSFKN--NLVDIIQQNKERWKELAAQGELDLHKN-----------SEDL---EEKHADTHP-------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P54750-1", "uniprot_id": "PDE1A_HUMAN", "id": "P54750-1", "name": "Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A", "aln": "----------------------------------------------------MGSSATEIEELENTTFKYLTGEQTEKM----------------WQRLKG------------------ILRCLVKQLERGDVNVVDLKKNIEYAASVLEAVYIDETR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RLLDTEDELSDIQTDSVPSEVRDWLASTFTRKMGMTKKKPEEKPKFRSIVHAVQAGIFVERMYRKTYHMVGLAYPAAVIVTLKDVDKWSFDVFALNEAS----GEHSLKFMIYELFTRYDLINRFKIPVSCLITFAEALEVGYSKYKNPYHNLIHAADVTQTVHYIMLHTGIMHWLTELEILAMVFAAAIHDYEHTGTTNNFHIQTRSDVAILYNDRSVLENHHVSAAYRLMQEEEMNILINLSKDDWRDLRNLVIEMVLSTDMSGHFQQIKNIRNSLQQPEG-IDRAKTMSLILHAADISHPAKSWKLHYRWTMALMEEFFLQGDKEAELGLPFSPLCDRKSTMVAQSQIGFIDFIVEPTFSLLTDSTEKIVIP-----------LIEEASKAETSSYVASSSTTIVGLHIADALRRSNTKGSMSDGSYSPDYSLAAVDLKSFKN--NLVDIIQQNKERWKELAAQEARTSSQK-----------CEFI------HQ-----------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58GHP9-1", "uniprot_id": "A0AC58GHP9_DANRE", "id": "A0AC58GHP9-1", "name": "Phosphodiesterase", "aln": "--------------MGTFSSKLSRRNIATVKPKEPDDGRANRDPTESQTRVIKNAVQRVSREVQRASVITEGGDSVHSMTVMQAGSRALRH---RWGSVRGQSQGLAERDASDSKDPKIRLRCLVKQLDKGEVNVVDLRKNIEYAASVLEAVYIDETR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RLLDTEDELSDIQADSVPMEVRDWLASTFTRKMGVVRRRPEEKPRFRSIVHAVQAGIFVERMYRRTSNMAGLTYPPSVITALKDVDKWSFDVFKLQEAS----SDHALKFLVYELLTRYDLISRFRIPVSSLVSFVEALEIGYSKHRNPYHNLIHAADVTQTAHYLMLHTGVMHWLTELEILAMVFAAAIHDFEHTGTTNNFHIQTRSEVAILYNDRSVLENHHVSAAYRLMQEDEMNILVNLSKDDWRELRTLVIEMVMSTDMSCHFQQIKTMRNSLQQPEG-IDKAKALSLMLHAADISHPAKGWKLHYRWTQALMEEFFRQGDKEAELGLPFSPLCDRKATMIAQSQIGFIDFIVEPTFSVLVDTTEKIISP-----------LIEEAVK--SGGVRRSSLTGRGSAAVVESVQRHSDRGSNDECGGSTDYSLCGIDQKHVRH--LLSEIIQNNKERWKELSVQELANKQHERMSDLQEEPMRSTQLTLSQENHDSESKSLNELNNTDSTHSSQDSLDQSSQSPTEGAGDASPEEHSSETLPWNGKSA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "B7YZV4-1", "uniprot_id": "PDE1_DROME", "id": "B7YZV4-1", "name": "Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1", "aln": "MQPSSPNATNYLADNIQISSANLSQTEMVVGRDSADYTAMHSINVGVGNSFLRGDTDIPQESGHSFETPSNMSFTAGQWDTESLPPVDTPD---ALNKAAG------------------RIRSLLRRMDHETVAYEDMQRNLHYAARVLEAVFIDESREGCNGNCKNLNCSRHSHGRDDQQQDNNNSNRSCSLQEASPGGAGAGVTPGADNQDSIESRTKGVSQAPQTHSGPTGPPSNTSSETIAQPAPKLQPALETVRESVMEESPSKDPGDKGPPPPASTSTLTSQTTTSSSATAEPSAKAAESQAGSAGSSGSCSNPAAVHRQRRLRTPTWARSMSTNKTRLADEDDELSEVQPDAVPPEVREWLASTFTRQMATSRRKSDEKPKFRSVAHAIRAGIFVDRMYRRVSSSALTAFPPDVVRLLKNLDDWTFDVFALTEAA----SGQVVKYVAYELFNRYGSIHKFKIAPGILEAFLHRVEEGYCRYRNPYHNNLHAVDVMQTIHYCLCNTGLMNWLTDLEIFASLLAALLHDYEHTGTTNNFHVMSGSETALLYNDRAVLENHHASASFRLLREDEYNILSHLSREEFRELRGLVIEMVLGTDMTNHFQQMKAMRQLLTLQEATIDKQKVLSLVLHCCDISHPAKQWGVHHRWTMLLLEEFFRQGDLEKELGLPFSPLCDRNNTLVAESQICFIDFIVEPSMGVMSDMLELILAPIAPMNKSKPATLVEHETTANSTTNSAIVIPNSGITPSMDKPRDHRTEAKTTAAECLARKSVTGTTASKFNIPKPWLTCLVENKRIWKEQAVKDAEARALAT---------AAEEAAAAAAAEAEESKPETETADGEQSEPAAEPADGAAA--------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P06776-1", "uniprot_id": "PDE2_YEAST", "id": "P06776-1", "name": "3',5'-cyclic-nucleotide phosphodiesterase 2", "aln": "-----------MSTLFLIGIHEIEKSQTIVQNEHYFDRVIELQDLDSLMVALYKDRVSPFPNVHNFETGVSIVLYDPSK---------FQLSVR-------------------------QLDVLFKRFFP-SFNISAIDHTREENLQRLECVERENSICRN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RITRINHWMYHHHDDTPDGINKNSYGTVNGNSVPTQACEANIYTLLLHLNDSKAQHLRKASVPRLIRNIEFMSFLSDPIEKISQEGSHYWNILSTWDFCALSLSTQELIWCGFTLIKKLSKDAKVLIADNKLLLLLFTLESSYHQVN-KFHNFRHAIDVMQATWRLCTY---LLKDNPVQTLLLCMAAIGHDVGHPGTNNQLLCNCESEVAQNFKNVSILENFHR-ELFQQLLSEHWPQLLSISKKKF----DFISEAILATDMALHSQYEDRLMHENP-----MKQITLISLIIKAADISNVTRTLSISARWAYLITLEFN------------------------DCALLETFHKAHRPEQDCFGDSYKNVDSP-----------------------KEDLESIQNILVNVTDPDDIIKDHPHIPNGQIFFINTFAEVFFNALSQKFSGLKFLSDNVKINKEYWMKHKKPQ-------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . : *.::: . : :. . **.* ::: *: :. : . : *: :: .:. ..: ..: . : : .: : : * :: . : :.: .. :::: : . . : : : : *:.: . :. *. . * : :* .* : . :** ** ** *: : . :: : :** ** *.**.*:: *:.* ::: ::***.* :: : .:. * :*:..: :: * ::.***: * * . : :.: . :**:::..***: :: : **: : ** : : :. .* . : * : : * : . :. . . : :* . ** : ", "identical_positions": 56, "similar_positions": 149, "identity": "6.26%" }, { "cls_id": "homologset.agr.MGI:1201793", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P03950-1", "uniprot_id": "ANGI_HUMAN", "id": "P03950-1", "name": "Angiogenin", "aln": "MVMGLGVLLLVFVLGLGLTPP-TLAQDNSRYTHFLTQHYDAKPQGRDDRYCESIMRRRGLT-----SPCKDINTFIHGNKRSIKAICEN-KNGNPHRENLRISKSSFQVTTCKLHGGSPWPPCQYRATAGFRNVVVACENGLPVHLDQSIFRRP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F7F7P3-1", "uniprot_id": "F7F7P3_RAT", "id": "F7F7P3-1", "name": "", "aln": "MEMSLRPLLLVFVLSLVATPS-TLAQDDPRYTKFLTQHYDAKPKGRDARYCESMMKRRGLT-----SPCKEVNTFIHGNKGSIKAVCG--ANGSPYGENLRISQSPFQITTCKHTGGSPRPPCRYRASAGFRHVVIACENGLPVHFDESFISLY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97802-1", "uniprot_id": "ANG3_MOUSE", "id": "P97802-1", "name": "Angiogenin-3", "aln": "MVMSPGSLLLVFLLSLDVIPP-TLAQDNYRYIKFLTQHYDAKPTGRDYRYCESMMKKRKLT-----SPCKEVNTFIHDTKNNIKAICG--ENGRPYGVNFRISNSRFQVTTCTHKGGSPRPPCQYNAFKDFRYIVIACEDGWPVHFDESFISP-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A5HAK0-1", "uniprot_id": "RNSL3_DANRE", "id": "A5HAK0-1", "name": "Ribonuclease-like 3", "aln": "MGIHQCTAVVLLLLCASLSTYGQPAEIRRRYEHFLTQHVYG---GITEQTCDRVMRQRRITRFPTGNDCKEVNTFIQANGNHVRTVCTGGGTRQTDNRDLYMSNNQFTVITCTLRSGERHPNCRYRGKESSRKIVVACEGEWPTHYEKGVIV--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : :::::* . *: ** :***** . * : *: :*::* :* . **::****: . ::::* . . :: :*:. * : **. .*. * *:*.. . * :*:***. *.* ::..: ", "identical_positions": 37, "similar_positions": 49, "identity": "24.03%" }, { "cls_id": "homologset.agr.MGI:1202063", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P49242-1", "uniprot_id": "RS3A_RAT", "id": "P49242-1", "name": "Small ribosomal subunit protein eS1", "aln": "MAVGKNKRLTKGGKKGAKKKVVDPFSKKDWYDVKAPAMFNIRNIGKTLVTRTQGTKIASDGLKGRVFEVSLADLQND---EVAFRKFKLITEDVQGKNCLTNFHGMDLTRDKMCSMVKKWQTMIEAHVDVKTTDGYLLRLFCVGFTKKRNNQIRKTSYAQHQQVRQIRKKMMEIMTREVQTNDLKEVVNKLIPDSIGKDIEKACQSIYPLHDVFVRKVKMLKKPKFELGKLMELHGEGGSS---GKTTGDETGAKVERADGYEPPVQESV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P61247-1", "uniprot_id": "RS3A_HUMAN", "id": "P61247-1", "name": "Small ribosomal subunit protein eS1", "aln": "MAVGKNKRLTKGGKKGAKKKVVDPFSKKDWYDVKAPAMFNIRNIGKTLVTRTQGTKIASDGLKGRVFEVSLADLQND---EVAFRKFKLITEDVQGKNCLTNFHGMDLTRDKMCSMVKKWQTMIEAHVDVKTTDGYLLRLFCVGFTKKRNNQIRKTSYAQHQQVRQIRKKMMEIMTREVQTNDLKEVVNKLIPDSIGKDIEKACQSIYPLHDVFVRKVKMLKKPKFELGKLMELHGEGSSS---GKATGDETGAKVERADGYEPPVQESV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P97351-1", "uniprot_id": "RS3A_MOUSE", "id": "P97351-1", "name": "Small ribosomal subunit protein eS1", "aln": "MAVGKNKRLTKGGKKGAKKKVVDPFSKKDWYDVKAPAMFNIRNIGKTLVTRTQGTKIASDGLKGRVFEVSLADLQND---EVAFRKFKLITEDVQGKNCLTNFHGMDLTRDKMCSMVKKWQTMIEAHVDVKTTDGYLLRLFCVGFTKKRNNQIRKTSYAQHQQVRQIRKKMMEIMTREVQTNDLKEVVNKLIPDSIGKDIEKACQSIYPLHDVFVRKVKMLKKPKFELGKLMELHGEGGSS---GKAAGDETGAKVERADGYEPPVQESV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6PBY1-1", "uniprot_id": "RS3A_DANRE", "id": "Q6PBY1-1", "name": "Small ribosomal subunit protein eS1", "aln": "MAVGKNKRLTKGGKKGAKKKIVDPFSKKDWYDVKAPAMFNIRNLGKTLVTRTQGTRIASDGLKGRVFEVSLADLQND---EVAFRKFKLVTEDVQGKNCLTNFHGMDLTRDKMCSMVKKWQTMIEAHVDVKTTDGYLLRLFCVGFTKKRTNQIRKTSYAQHQQVRQIRKKMMEIMTREVQTNDLKEVVNKLIPDSVGKDIEKACQSIYPLHDVYVRKVKMLKKPKFELGKLMELHGEGGSTSAAAKPAEGDTGAKVERADGYEPPIQESV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P55830-1", "uniprot_id": "RS3A_DROME", "id": "P55830-1", "name": "Small ribosomal subunit protein eS1", "aln": "MAVGKNKGLSKGGKKGGKKKVVDPFSRKDWYDVKAPNMFQTRQIGKTLVNRTQGQRIASDYLKGRVFEVSLADLQKDIDPERSFRKFRLIAEDVQDRNVLCNFHGMDLTTDKYRSMVKKWQTLIEAIVEAKTVDGYLLRVFCIGFTAKDQQSQRKTCYAQQSQVRKIRARMTDIITNEVSGADLKQLVNKLALDSIAKDIEKSCQRIYPLHDVYIRKVKVLKKPRFDVSKLLELHGDGGGKS--VEAVVSSEGAVIDRPEGYEPPVQEAV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P23248-1", "uniprot_id": "RS3A2_YEAST", "id": "P23248-1", "name": "Small ribosomal subunit protein eS1B", "aln": "MAVGKNKRLSRG-KKGLKKKVVDPFTRKEWFDIKAPSTFENRNVGKTLVNKSTGLKNASDALKGRVVEVCLADLQGS--EDHSFRKVKLRVDEVQGKNLLTNFHGMDFTTDKLRSMVRKWQTLIEANVTVKTSDDYVLRIFAIAFTRKQANQVKRHSYAQSSHIRAIRKVISEILTREVQNSTLAQLTSKLIPEVINKEIENATKDIFPLQNIHVRKVKLLKQPKFDVGALMALHGEGSGE---------EKGKKVS---GFKDEVLETV", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P33442-1", "uniprot_id": "RS3A1_YEAST", "id": "P33442-1", "name": "Small ribosomal subunit protein eS1A", "aln": "MAVGKNKRLSKG-KKGQKKRVVDPFTRKEWFDIKAPSTFENRNVGKTLVNKSTGLKSASDALKGRVVEVCLADLQGS--EDHSFRKIKLRVDEVQGKNLLTNFHGMDFTTDKLRSMVRKWQTLIEANVTVKTSDDYVLRIFAIAFTRKQANQVKRHSYAQSSHIRAIRKVISEILTKEVQGSTLAQLTSKLIPEVINKEIENATKDIFPLQNIHVRKVKLLKQPKFDVGALMALHGEGSGE---------EKGKKVT---GFKDEVLETV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******* *::* *** **::****::*:*:*:*** *: *::*****.:: * : *** *****.**.***** . : :***.:* .::**.:* * ******:* ** ***:****:*** * .** *.*:**:*.:.** * :. :: .*** .::* ** : :*:*.**. * ::..** : : *:**:: : *:**:::.:****:**:*:*::. *: ***:*.. . * : *:: : *:*", "identical_positions": 121, "similar_positions": 83, "identity": "44.81%" }, { "cls_id": "homologset.agr.MGI:1202064", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O55225-1", "uniprot_id": "OTOG_MOUSE", "id": "O55225-1", "name": "Otogelin", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------MGARMPRRCLLLLS-------CFCLLRVESTAE------VQHQASALTWKISA--------------------------ELQQEPAPEPSHTYQEMSLAVEDVTTVMEG----QEAEALAASAMSSWERRLHRAKCAPSYLFSCFNGGECVHPALCDCRRFN-----------------------------------------------------------------------------------------------ATGPRCQLVYNVGPERD-------------------------------------------------SICRTWGQHHVETFDGLYYYFSGKGSYTLVGHHEPEGQS-FSIQVHNDPQCGSAHYTCPRSVSLFLSGEREICLAK-EVTHGGVRVQLPQVVGGVQLQQLAGYVIARHPSAFTLAWDGIS-AIYIKMSPEFLGWTHGLCGNNNADPQDDLVTSYGKVTDDVGEFVHSWQEQVPNSPPGPVTTSLPRPPCLQQSPASMQGVYERCEVLLR-PPFDTCHAYVSPLPFAASCTSDLCQSG---GDEATWCRALMEYARACAQAGRPLQGWRTQLSQCTVHCKEKAFIYNECIACCPASCQSRASCVDSEITCVDGCYCPNGLIFEDGGCMSPAECPCEFHGTLHPPGSVVTEDCNACTCTAGKWVCSSSVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQN-------APCGLNQDGACVQSVSV--ILHQDPRRQVTLTQAGDVLLFDQYKITPP--YSDDAFEIRRLSSVFLRVRTNVGVRILYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACVPLVPGSL-LDPCDVHLQAASYALQSCSVLTGELFAPCSAYLSPIPYFEQCRRDACRCG---QPCLCATLAHYARLCRRHGLPVDFRAHLPACALSCEATKEYSPCVTLCAPTCQDLASPDVCGANGGGNFSREECVEGCTCPPDTFLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPS----LGHCHCKDGVMSCDSRAP---AAACPAGQVFVNCSELHPDPELSR----ERTCEQQLLNLSVPARGPCLSGCACPQGLLRHG--DACFPPEECPCTWKGKEYFPGDQVVSSCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPYDFVGACKVHLVKSTSELS--FSVMVEDVNCYGSGVICRKSISINVG----SSLIIFDDDSGDPSP----------ESFLDEKQAVHIWRAGFFTLVHFPREHITLLWDQRTTVHVQAGPQWQGQLVGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAV-ECPDTPDPRDTCVLNPLREPFARKECGILLSEVFETCHPVVDVTWFYSNCLTDTCGCSRGGDCECFCASVAAYAHQCCQHGVVIDWRTPRICPYDCDFFNKALGKGPYQLSSVAAG---GTLVATKAVDSDIALVRAEDLAPGDISSFLLTAALYKAKAHDPDVVSLEAADRPNFFLHTTANGSIGLAKWQRDEAFHQHASFSLHRGTWQAG-LVALESLAKPGSFLHSSGLELALRAYEHTEVFRGGALFRLLDAKPLGAAYPTCEWRYDACASPCFQTCRDPRATSCQDVPRVEG-----------CVPVCPTPKVLDEVTQRCVYLEDCVEP--------------------------------------APRGPTETLGNETLVPGQVPPTTSAEQ-QLPQGLPGASAYSPAPVPVAP----------------PTSAPNPPMAATEGQAPSPGSTQPTLQTPLGLTTSNFPAGHTEATAREEGAAS----LLTTSHPPGFSSSLPSSLQMPTSGIVS---GATETTKVTITFTGSPNTTVASRSPP-IPRFPLMTKAVT----------------------VPSHDSFPVKTTPL------QPSWLWSLSSRPMTSLG------------ATSWPPTSPGSH---LSTAVTKVANKTMTSLSVLAQS-------------------TSSSSQPLAAV-TTAHRAPASPLVTKGLEV------VSATEKGEAGHSQLTELPVSPPPSPAPIDLP--HPAQHTTTAPGPSALSPGILAAGSPSTGAHR-----------------------------------PGATALASLEPTRPPHLLSGLPLDTSLPLAKVGTSAPVATPGS------------KGYIPTPPPQHQATTLATAMTVSPLTQS-LSLTVPLMSAVEEQAHSPSPKPPQGTGMAPDQMLGATLPSFGASSVIAGVPPTVSAAPRKS--------TTQRAAILSKKVSPPTLISDSVQG----------------GFTELTPIVSHTVTPLATE-----------AEGPRAGTVPLVPTTYSLSRVSARTASREGPLVLLPQLAEAYGTPAGLQPQED------LVRQATTEQSGRSAPAKS----------IAEESMEA-----EVNTSATCVP------IAEQDCVRHICLEGQLIRVNQTQHCP-QGAVRPRCGVLGLAVRVGGDRCCPQWECACR-----CSIFPDLSFVTFDGSHAALFKEAIYVLSQSPDETISVHVLDCKSAN--LGHLNWPPFCLVILNVTHLAHHVSIDRFNRKVTVDSQVVWPPMSRYGFRIEDTGHMYIVRTPSHIQIQWLHSSGLMILEASKVS-KTQGHGLCGICDGDAANDLTLKDGSVLGEAEDPAPFLDSWQVPSSLTSEGQTRFRPDSCATADCSPCLRMVSNRTFSACHSFVSPESFCELWIRDTKY----------VQQPCVALTVYVAMCHKFH---VCIEWRGSDYCPFLCSSDSTYQACVAACEPPDTCQDGILGPLDPEQCQVLGEGCVCTEGTILHRRHSALCIPEDKCACTDSTGVPRALGETWNSSLSGCCQQQCQAPDTIIPVDLDCPGPRPESCPRFG------------------------------------------------------------------------------------------------------------------------------------------------------EVILLQPTEDPCCLGS-----------------VCVCNQTLCEG------------LAPTCRPGHSLITHFQEDSCCP------------SYSCECDPGLCEAEQVPTCREDQILIEGRLGDSCCTS------YFCGCGECSD--------PMPECQEGEALTVHRNTTELCCPLYQ-------CVCENFRCPQVQCGMGTSLVEVWSPDRCCPYKSCECDCDTIPVPRCHLWEKSQLDEEFMHSVENVCGCAKYECVKAP--VCLSRELGVMQPGQTVVELSA------DGVCHTSRCTDVLDPLTN-FYQINITS---------------VLCDMHCEANQEYDHPRDLAACCGSCRNVS---------------------CLFTFPNGTTSLFLPGASWIADCARHHCGSTPLGAVLVRSPISCPPFNETECAKVGG------------------SVVPSLEGCCRAC------------------------KEDGRSCKKVTIRMT----------IRKNDCRSNTPVN-LVSCDGRCPSASIYNHNINTYARFCKCCREVGLQRRSVQLFCATNATWVPYTVQEPTDCACQWS-----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZCV6-1", "uniprot_id": "D3ZCV6_RAT", "id": "D3ZCV6-1", "name": "Otogelin", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------MGARAPRLCLLLS--------CFCLLRVEPAAELEFKRTVQHQASALTWKAGE--------------------------ELQQEPAPEPSHSYQ-MPFAVEDVTTAMEG----QDAEAFDAPAMSSWERRLHRAKCAPSYLFSCFNGGECVHPALCDCRRFN-----------------------------------------------------------------------------------------------ATGPRCQLVYNAGPERD-------------------------------------------------SICRAWGQHHVETFDGLYYYFSGKGSYMLVGHHEPEGQS-FSIQVHNDPQCGPAHYTCPRSVSLFLSGEREICLAK-EVTHGGIRIQLPQVVAGVQLQQLAGYVIARYPSAFTLAWDGAS-AVYIKMSPEFVGWTHGLCGNNNADPQDDLVTSYGKLTDDIGEFVHSWQEQVPNSPPVPVMSSLPRPPCLQQSPASMQGVYERCEVLLR-SPFDACHAYVSPLPFTASCTSDLCQSG---GDEATWCRALTEYARACAQAGRPLQGWRTQLSQCTVRCKEKIFIYNECIACCPASCQSHASCVDSEIACVDGCYCPNGLIFEDGVCMSPAECPCEFHGTLHPPGSVVTEDCNTCTCTAGKWVCSSSVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQN-------APCGLNQDGACVQSVSV--ILHQDPRRQVTLTQAGDVLLFDQYKITPP--YSDDAFEIQKLSSVFLRVRTNVGVRILYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACVPLAPGSL-LDPCDVHLQAASYALQACSVLTGELFAPCSAYLSPIPYFEQCRRDACRCG---QPCLCATLAHYARLCRRHGLPVDFRARLPACALSCEATKEYSPCVALCTQTCQDLASPDVCGANGGGNFSRDECVEGCTCPPDTFLDTQTDLCVPRNQCSCHFQGVDYPPGDSDIPS----LGHCHCKDGVMSCDSRAP---AATCPAGQVFVNCSELHPDPELSR----ERTCEQQLLNLSLPARGPCLSGCACPLGLLRHG--DSCFPPEECPCTWKGKEYFPGDQVVSSCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSELS--FSVMVEDVNCYSAGVICRKSISINVG----SSLIIFDDDSGDPSP----------ESFLDEKQAVHIWRAGFFTLVHFPREHITLLWDQRTTVHVQAGPQWQGQLVGLCGNFDLKTVNEMRTPENLELTNPQEFGSSWAAV-ECPDTPDPRDTCVLNPLREPFARKECGILLSEVFETCHPVVDVTWFYSNCLTDTCGCSRGGDCECFCASVAAYAHQCCQHGVVIDWRTPRICPYDCDFFNKALGKGPYQLSSVMAG---SALVAMRAVDGDIALVRAEDLVPGDISSFLLTAALSKAKAHDPDVVSLEAADRPNFYLHVTANGSIRLAKWRRDEAFHQHASFSLHRGTWQAG-LVALESLAKPGSFLQSSGLKLALRTYEHTEAFRGGALFRLLDAKPSGAAYPICEWHYDACASPCFQTCRDPQAASCQDVPRVEG-----------CVPVCPTPKVLDEVTQRCVYLEDCVEP--------------------------------------ALRGPKETLGNETLAPGQVLPTTSDKQ-QLPQEPPGASTHIPVLDPLAP----------------LTSAPNPPMAATEGPVASPGSTQPTLQTSLGLTTSNLPAGHTEATAREEGAAS----LLATSPPPGSSSSLPSSLQTPTSGILS---STTETTKVTLTFAGSPNTTVTSRSPP-VPRFPLMTKAVT----------------------VPSHDSFPVKTTPL------RPS--WSLSSRPTTSPG------------VTSWPPTSLGSH---LSTVVTNVTNKTETSLSVLAQS-------------------TKSSSQPLS----TAYRAPASPLVTKGLEG------ASATEKGDAGHSQLTELPVSPPPSSAPIDLP--HPAQHTTTAPGSPALSPGILGAGSPSTGAHG-----------------------------------LGTTALASLETTRPPHLLSGLPPDTSLPLAKVGTSAPVATPAS------------KGYVPTPPPQHWATTSATAMTVTPLTQTTLSLTAPLMSAVEEQAHSPSPTAPHITAMT---------PSFGASAGTAGVPPMVSVAPQKS--------TTQRAAILSKKVSPPTLISDSVQG----------------GFTELTPTVSHTVAPLVTE-----------AEGPQAGTVPLVPTTHSLSRVSARTASREGPLVLLPQLAEAHGTPAGLQPQED------LVRQATTEQTGRSAPAQS----------IAEGSMEA-----EGNTSAICVP------IAEQDCVRHICLEGQLIRVNQTQHCP-QGAVRPRCGVLGLAVRVGGDHCCPLWECACR-----CSIFPDLSFVTFDGSHAALFKEAIYILSQSPDEIISVHALDCKSAN--LGHLNWPPFCLVILNVTHLTHHISIDRFNRKVTVDSQVVWPPMSRYGFRIEDTGHMYIVQTPSHIQIQWLHSSGLMILEASKAS-KTQGHGLCGICDGDTANDLTLKDGSVLGEAEDPALFLDSWQVPSSLTSEGQTRFRPDSCSTADCSPCLRMVSNRTFSACHSFVSPESFCELWIRDTKY----------VQQPCVALTVYVAMCHKFH---VCIEWRGSDYCPFLCSSDSTYQACVAACEPPETCQDGVLGPLDPEQCQVLGEGCVCSEGTILHRRHSALCIPEDKCACTDSTGVPRALGETWNSSLSGCCQQQCQAPDTITPMDPDCPGPRPESCPRFG------------------------------------------------------------------------------------------------------------------------------------------------------EVILLQPTEDPCCLGS-----------------VCVCNQTLCEG------------LAPTCRPGHRLIPHFQEDSCCP------------SYSCECDPGLCEAEQVPTCRQDQVLIEGRLGDSCCPS------YFCGCGECPD--------AMPECQEGEVLTVHRNSTELCCPLYQ-------CVCESFRCPQIQCGMGTSLVEVWSPDRCCPYKSCECDCDTIPVPRCHLWEKSQLDEEFMHSVENVCGCAKYECVKAP--VCLSRELGVMQPGQTVVELSA------DGVCHTSRCTDVLDPLTN-FYQINITS---------------VLCDMHCEANQEYDHPRDLAACCGSCRNVS---------------------CLFTFPNGTTSLFLPGASWIADCARHHCGSTPLGAVLVRSPISCPPLNETECAKVGG------------------SVVPSLEGCCRTC------------------------KEDGRSCKKVTIRMT----------IRKNDCRSNTPVN-LVSCDGRCPSASIYNHNINTYARFCKCCREVGLQRRSVQLFCATNATWVPYTVQEPTDCACQWS-----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6ZRI0-1", "uniprot_id": "OTOG_HUMAN", "id": "Q6ZRI0-1", "name": "Otogelin", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------MGVLASALCWLLCVWLPWGEQAAESLRVQRLGERVVDSGRSGARGMRNVKGMR--------------------------NGPAQTRVSSSSSHQEATLAMGDKATVVGG----QQAEAPDSVAMSSWERRLHRAKCAPSYLFSCFNGGECVHPAFCDCRRFN-----------------------------------------------------------------------------------------------ATGPRCQMVYNAGPERD-------------------------------------------------SICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQS-FSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAK-EVTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGAS-AVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLR-PPFDACHAYVSPLPFTASCTSDLCQSM---GDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQN-------APCGLNQDGACVQSVSV--ILHQDPRRQVTLTQAGDVLLFDQYKIIPP--YTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSPLVSGSP-LDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRCG---QPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPS----LGHCHCKDGVMSCDSRAP---AAACPAGQVFVNCSDLHTDLELSR----ERTCEQQLLNLSVSARGPCLSGCACPQGLLRHG--DACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVS--FSVIVENVNCYSSGMICRKFISINVG----NSLIVFDDDSGNPSP----------ESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAV-ECPDTLDPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFNKVLGKGPYQLSSLAAG---GALVGMKAVGDDIVLVRTEDVAPADIVSFLLTAALYKAKAHDPDVVSLEAADRPNFFLHVTANGSLELAKWQGRDTFQQHASFLLHRGTRQAG-LVALESLAKPSSFLYVSGAVLALRLYEHTEVFRRGTLFRLLDAKPSGAAYPICEWRYDACASPCFQTCRDPRAASCRDVPRVEG-----------CVPVCPTPQVLDEVTQRCVYLEDCVEP--------------------------------------AVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAP----------------LTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTAS----LLAIPHTPE-SSSLPVALQTPTPGMVS---GAMETTRVTVIFAGSPNITVSSRSPP-APRFPLMTKAVT----------------------VRGHGSLPVRTTPP------QPSLTASPSSRPVASPG------------AISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQS-------------------ASSPSTPLTVAGTAAEQVPVSPLATRSLEI------VLSTEKGEAGHSQPMGSPASPQPHPLPSAPP--RPAQHTTMATRSPALPPETPAAASLSTATDG-----------------------------------LAATPFMSLESTRPSQLLSGLPPDTSLPLAKVGTSAPVATPGP------------KASVITTPLQPQATTLPAQT---------LSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKS--------TTGKVAILSKQVSLPTSMYGSAEG----------------GPTELTPATSHPLTPLVAE-----------PEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLLPQLAEAHGTSAGPHLAAE------PVDEATTEPSGRSAPALS----------IVEGLAEALATTTEANTSTTCVP------IAEQDCVRHICLEGQLIRVNQSQHCP-QGAAPPRCGILGLAVRVGGDRCCPLWECACR-----CSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSAN--LGHLNWPPFCLVMLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTS-KAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKY----------VQQPCVALTVYVAMCHKFH---VCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRPESCLRFG------------------------------------------------------------------------------------------------------------------------------------------------------EVALLLPTKDPCCLGT-----------------VCVCNQTLCEG------------LAPTCRPGHRLLTHFQEDSCCP------------SYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTS------YFCACGDCPD--------SIPECQEGEALTVHRNTTELCCPLYQ-------CVCENFRCPQVQCGLGTALVEVWSPDRCCPYKSCECDCDTIPVPRCHLWEKSQLDEEFMHSVENVCGCAKYECVKAP--VCLSRELGVMQPGQTVVELSA------DGVCHTSRCTTVLDPLTN-FYQINTTS---------------VLCDIHCEANQEYEHPRDLAACCGSCRNVS---------------------CLFTFPNGTTSLFLPGASWIADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGG------------------SVVPSLEGCCRTC------------------------KEDGRSCKKVTIRMT----------IRKNECRSSTPVN-LVSCDGRCPSASIYNYNINTYARFCKCCREVGLQRRSVQLFCATNATWVPYTVQEPTDCACQWS-----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58G5C7-1", "uniprot_id": "A0AC58G5C7_DANRE", "id": "A0AC58G5C7-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------MFISIYYANEQERGTGVISSSGDATNTQRREREERPVGREYASVEQRCETVRGEANSRSDSHESRMDPILTPGKKLFLLYLLFFILIYQAHITWGTESLNLTHQHDFENSSESSRIMLEKWDPAFQTEQ----RTLESNTSSAEQAEAQKPSTRRASGECASPCLNGGRCVHPDSCNCTLYQ-----------------------------------------------------------------------------------------------AAGTRCQTVPNLGFERE-------------------------------------------------MTCRSWGQYNYETFDGLYYYFPGKCSYTLLRDCEDNARSSVHIQVHNDPECSSSPYSCTRSISLFLPWEGEIRLQHFSVTFKGQSVLLPHHIHDVELERISDYIVVSQPHVFTLAWQGLTSSVYIKMSPEFVGHTCGLCGNFNADTQDDLKTSYGVFTQDLAMFGNSWAEEEPELARCTVVPSLYPSPCATLDPHVLLKVEEVCSTLLR-EPFQSCHEFVSPYSYMASCSNDLCLSG---PNGAVVCQVFTEYARACAHADHPLHDWRTHFPVCNVDCPDELLFR-ECITCCPMHCKIEQMCIDSKLQCLDGCYCPDDLIFEDGVCVKASDCPCEHHGMLYPSGHIIQEDCNNCTCFGGIWNCTEHNCPGECSVTGDMFFQSFDGRVYTFPATCQYVLAKSRNSGKFTVTIQN-------APCGANLDGACIQSVNL--VVNEDPRTEITMSHSGEVFLASQFRISLP--YSDDMFQIQELSSMFVQVKLSQGLWLQYNWKEFRLYLQLEEQWRDNTLGLCGTFNGNIQDDFLAPSGMIESTPFLFGNAWRVSSACVPRPSLPQ-LDPCDTHQQAASYAVEKCDVLTQEVFSACHEYVSPVGFQLQCRADVCKCG---ALCLCSILAHYARTCRRHGVIIEFRSHLPECAVSCPSTMEYGVCVSACQRRCLFLSLPQPCG---------DECEEGCVCPEGTYFNMHTHTCVPRNECPCSFLGADYSPGDVIITS----SGVQICQDGKLVSQTSII---ETLCPAGQFYEDCGNRVDGPSASKGLACEQTCETYLLNLTCSTHEPCVPGCVCPAGLLKHG--DECFKPRACPCLWKGKEYYPGDKVSSPCHQCVCQHGTFQCEFRPCPSMCTAYGDRHYRTFDGFLFDYIGVCKVYLVKSSLDAM--LTVTAENVDCFESGVICRKSLHISVG----RSFIVFDDDTGRPNP----------SSVID-RQRAYIWQAGYYTIVHLLGEDLTVLWDRKTTIHIQAGPRWQGRLTGLCGNFDQKTANEMRTPENIDSSTPQEFGNSWTAA-ECVNSPDIRHPCNLNPLREPFAKRQCGILLSEVFQVCHPVVDVTWFYMNCLVDTCGCNRGGDCECFCTSVAAYAHRCCQKGIPIDWRSPSICPYDCEYYNKALGKGPLKLLTYRER---GTLLAANKTSGLVFPKRDLTSVDENLVLFMMTPGISKARPHDSSLVSFEAADRPNYFLKAEQGSQLRLGKWEDTPAFWDAATFVLHRDTWIPG-FDSLESLARPGFFLHFMLSRLQLQKYSHSDRYRRATLFKLTGAIPHYPMGPRCQWRFESCVRPCFRTCSDPSGLSCTSILKIEG-----------CLPQCPSHMVLDEVTHRCVSLEDCIRPPVVPPF--TLPSTTISSTPFSEDYTSSIPAVSTALISTAVSESSATTTPTTHMPTTEKPTTSPIRPEVVEVITTLTTSSSSWSPLASTERTTKAPSITSSPTSSTTLYTSPVSISAPVSVTSTTSSPTESSTPFTRTTTIPSQPSSSPVLRSTSSSEQTRVSTLPVLPVSTSMGPTEATSPTVKVSSPLTSITETARVSEAITPTEKTTTPTVSSSGISQFPAESISMTKFTSLSTTTPVLEWRTSGTTAEMAPSTSLDTLKTPESTSETQKPSYTTTIPTSPTDTKASTTYITVKSTSSAFATPPATQTTLYTPSTTSEQPETSKTTVSFSTAAPTSLTTVSSQAPAF-----VPTKTTAKTTYQPTSVIYTYPDGPTTDRALQTDWRVIQTTSTQLELTETSQISVRTAETPLTTYTTMPPTWAPTEETTTLLTSQMSPTDKTTSRVPSTSTTLGYTESSWSLS--STTSLYTEKVSTSPIHPHYTTTVATTPALSEISSASPSILTSSVSQTTSISQTPTITTETAVTSEKPLLTSTAAEEEVVSTTQTSTTTHLTIHLDTETTKASLDTDRAVITTAATAQTPTLVHETSSTIPSTMAPRLTTRITPVLTSRVGVDTIRQTPQDVATTSISPPTRIETTMTTSTTVSTEKETSVSTTIPSTAAASSTLTTPIPEIPEFTSGFTEYTAVSGSTTTLPSFT-----------GTTPTRTGTTTTPVASVLTQTTISTHLPTSSIVTTSSPITSSSTSTEHHLVDESPMVTTLPPTPDTAQTTRSTSVKTSLPYTIETEHWMTSQTQAVPKTTAHEPSRVCTAPY---SEVVDECTKLICVSGQLLLFNKSQSCP-YDPTPPNCGLLGFAVLVNGDKCCPRWDCPCR-----CSVFPDLNLITFDGKSVAIYKAALYVVTQLPNETVSILVQECSGPDD-TLVWNFTNLCLAALNITHKSNEVLVNRLQRRLYVNSRYAKPRFKKYGFEILDTGNMYLIRSPAGLKIQWFHTTGMMVIEMDSYNNRLPTMGLCGSCDGNPLNDLTLSNGTVVPEQEDPAVFIDSWQIPNTTSYVSNSRRREVNCTTSDCSQCFNMLNNNTFTLCHAYVPPGVFCEMWVRDVEY----------VNNPCIALAAYAASCHKFN---ICMEWRSSDFCPFVCPGNLRYQACLPACTAP-SCPNQEF-EFVPEQCTGLSEGCVCPEGTLLHRPYSALCIPPSKCACTDSFGAPRALGEVWKASLDGCCMYKCEN-DSIVPVEYNCSNIPQPVCTRTG------------------------------------------------------------------------------------------------------------------------------------------------------EITVNLADDSSCCPHK-----------------ACVCNQSMCEA------------APTGCKYGEKMVSYYRQDSCCP------------EYLCECDPDQCVLD-IPVCREDQTLIATRADGSCCLA------HICMCDKCPE--------AVPVCQDGELLIVDTNSTERCCPAYH-------CLCEASRCLDITCPVGMAVVSARDPEECCPLQTCECACEKLLRPKCSLGQSMQLDRAFLSDPENICACKRFICVREA--VCVDGERGVMRPGQTLVEHRD------QGVCYATQCTHTLDSATG-FYVLRSTG---------------TNCTARCQPNQIYIPPKDPSSCCGTCKNIS---------------------CLLRNENGSVAMYKPGRSWVSDCLRYDCSDTLAGPVLVTHPYSCPPFNETECMKIGG------------------TIVSYMDGCCKTCAVNSLFPFSVSPLKPTVNTNCEQGKEDGKSCQKVTVRMT----------IRKNDCRSNRPVN-IVSCDGKCPSASIYNYNINTYARFCKCCREMGLQRRSVQLYCSGNSTWVSYTIQEPTDCSCQWS-----------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VU94-1", "uniprot_id": "Q9VU94_DROME", "id": "Q9VU94-1", "name": "", "aln": "MANKVIFVALWLLFISSVLTENGDIIITDDDDEDINPLLQAAPEVVDKENERNERHISFNILKAPAVSARYTYGGSEGGRSGFGGGYGVGGGGGGGYGGIKTSHAAGGLLTKTLGFLGMGGQGSQGNFYGGGGHFLAAFGKCSALQLPSNVQSECHNGRCKVFCPTGYSFAQDVSVLEMFCSNDGWIIGNSVFAEVPPCQAQCTPPCQNNGICISAGVCQCPENYYG------PLCQQKKSICASFPKAPKNSKVSCKNNMCHAECMRGFQFPDGSGITNIECRNGQWVHTKTGLSKTPDCAPTCAPACQNGGQCISFNVCQCSKMFRGDHCQYNIDRCNVTNTNFNGNYKCAYEMDDARCTFSCPQVPGLKIQGRIDIEYKCNYLQGQYLPAPLPKCIFPPGYTVRSTSSMQGVTHQNGVYHRGMSGEMAYELQTERQKLLALLAKYRDLERRSEWWSSEETVVTMSSYSLYQSNNLDIVIDKTPRPALCTTWGGINMKTFDGLVFKAPLSCSHTLITDKVSGTFDIILKACPYGSGYGCAHTLKILWQSVLYTFEN--LNGTMQLTTPIKKLPMPVQVMGMKVMPVAQHVQIDLESVGLKLDWDHRQYVSVQAGPQMWGKVGGLCGTLDGDPNTDLTSRTGKKLATVKAFADAWRVEDRSELCQVENSAEMEFGMDSCEQSKLQKAVSVCERLLANEKLGDCIKPFNYDALIRTCMADYCNCANREHPESCNCDAIAMLAKECAFKGIKLEHGWRNLEICPISCGFG-RVYQACGPNVEPTCDSDLALPASKGACNEGCFCPEGTVQYKEACITRELCPCSLRGKEFKPESTVKKNCNTCTCKNGQWRCTEDKCGARCGAVGDPHYQTFDGKRYDFMGKCSYHLLKTQNTSVEAENVACSGAVSESMNFAAPDDPSCTKAVTIRFILRDGTPSVIKLDQGLTTIVNDKPIAKLPKMLGLGEVLIRRASSTFLTVEFADGIRVWWDG-VSRVYIDAPPSLRGQTQGLCGTFNSNTQDDFLTPEGDVETAVEPFADKWRTKDTCQFKAETHQGPHPCTLNPEKKAQAEKFCDWILQDIFQDCHFLVEPEQFYEDCLYDTCACKDEMSKCFCPILSAYGTECMRQGVKTGWRMSVKECAVKCPLGQVFDECGDGCALSCDDLPSKGSCKR---------ECVEGCRCPHGEYVNEDGE-CVPKKMCHCNFDGMSFRPGYKEVRPGEKFLDLCTCTDGVWDCQDAEPGDKDKYPPSSELRSKCAKQPYAEFTKCAPKEPKTCKN--MDKYVADSSDCLPGCVCMEGYVYDTSRLACVLPANCSCHHAGKSYDDGEKIKEDCNLCECRAGNWKCSKNGCESTCSVWGDSHFTTFDGHDFDFQGACDYVLAKGVFDNGDGFSITIQNVLCGTMGVTCSKSLEIALTGHAEESLLLSADSAYSTDPNKTPIKKLRDSVNSKGHNAFHIYKAGVFVVVEVIPLKLQVKWDEGTRVYVKLGNEWRQKVSGLCGNYNGNSLDDMQTPSMGLETSPMLFGHAWKLQPHCSAPVAPIDACKKHPERETWAQLKCGALKSDLFKECHAEVPLERFWKRCIFDTCACDQGGDCECLCTAVAAYADACAQKGINIRWRSQHFCPMQCDPHCSDYKACTPACAVETCDNFLDQGIAERMCNRENCLEGCHIKPCEDGFIYLNDTYRDCVPKAECKPVCMVRDGKTFYEGDITFTDSCATCRCSKRKEICSGVKCDVPATTGLPAPLVEGTTLPTPLATQNQTKCVKGWTRWCDKDRDTSDKSVRLNDEE-KVPRYDRMENVYGTCLKQYMTKVECRVKDTHEAPEQMDENVVCSLEEGLRCIGKCHDYELRAFCQCDEELEPELPKPTEKPQLGLACDAAVVEYKEFPGDCHKFLHCQPKGVEGGWIYVEKTCGEYMMFNPTMLICDHIATVTEIKPNCGLKPEPEPEFEPIKQCP-----------PGKIKSECANQCENTCHYYGSILKKRGLCQVGEHCKPGCVDELRPDCPKLGKFWRDEDTCVHADECPCMDKAEHYVQPHKPVLGEFEVC-QCIDNAFTCVPNKPEPVPKDEDDDLDLVSVVPIYPVTLTP------------------PLQCSPERLIPKIENPAHS----LPDSIFNASSQLAPEHGPKMARLTKEQPRGSWSPSINDQMQYLELNFAKPEPFYGVVMAGSPEFDNYVTLFKILHSHDGIAYHYLVDETEKPQMFNGPLDSRAPVQTLFKIPIEASSLRIYPLKWHGSIAMRVELLICGDKEEPKPVPTVSTILPITERPARLVDLECIDLMGVDEGKMYQDQVQSSSLWQQPNLGKKLQLLELLKLSTPLAWRPLANSQNEFIEFDFLEPRNISGFVTKGGPDGWVTGYKVMFSKKKPTWNTVLS--------TDGQARIFEANHDAETERRHHFKNPILTQYIKIVPAYWEKNINMRIEPLGCFLPYPEIQRQVPVEESKPTKCNICDGVSTSSSTTGCQCQDQLFWDGNTCVQHNLCPCIENYVSYPIGSKFENSACEDCVCVLGGHKNCKPKKCPPCLGGKLRPVITSDCFCKCEPCPKHQRLCPSSGDCIPEILWCNGVQDCADDEDASCSDSFTVEPDVSREKNETEVITCPVPVCPPQMKIRITEKKSRKMSKMFTFSKQVSIVDDGTTITKTKFISSKEQILAMPNRELDFQLEEQCDEFTCVPIPSKQVDKNETVTCTEPKCPEKYDVELDMSASKVGDCLRYSCVLRPNKDDVCEISGKSFTTFDGTVFKYGPCSHILARDIHSSSWSISVHQQCSDETRKVCHKVITIQDTEAGNELILLPHLKLKFNGYEFTVQQLINSPICKASFVVSQPGKTLLAVSTKYGFWVQLDDIGIVKVGISSKFIRTVDG-LCGYYNGNQKDDKRSPDGQIIPNTEK---FGDSWYDKRIPKDQCGDLKCPREMQAKALQLCN-IIHHPTFARCHKAVNYKQFLNNYCLEAACNCMMANNGDPAACKCNILESFVKKCLSVNPLVQLTTWRAVAQCEINCPSPLVHTDCYKRRCEP--SCDNVHGDDCPVLPDACFPGCYCPEGTVRKGPNCVPISECKDCVCNSLGASKYMTYDRKSFSFNGNCTYLLSRDVVLPGVHTFQVYVSMDDCKKLGQPTPVEGGSCAKSLHILNGDHVIHVQRVPQKPKSLQVLVDGFEVKKIPYKDSWISLRQVVGKELVLSLPESHVELTASFEDLIFSLGVPSIKYGSKMEGLCGDCNGNAGNDLQPNPAKKKAGVDVIQSWQADEPKLGLVEECLSEDVPKEHCIPLPPEKDPCLQFYNAELFGKCPLAVDPIAYVSACQQDICKPGNTQQGVCVALAAYAKECNQHGICTNWRRPQLCPYECPSDMVYEPCGCAKNCDTIKALSEFDAVSLKNEAVVHTVKTDEMCLSSERFEGCFCPPGKVMDGGQCVPEIACTKCDDGLHLPDEKWKKDKCTECQCDSKGKTTCVEKKCQVEENICAEGYRPETIVSVDECCPRYRCVPETKDPSKLCLAPLVPICGPGQFKKEKKDVNGCSQYICECIPKDQCEIIELRELLPGEIIVNVEEGCCPTQKIECKPETCPKAPVNCQERFYEVKTIKEPGMCCSKHSCVPPKDLCIVQYELDEATKFTKTVGDKWTHAKEVCKQETCSYGPDGNAQVVSTLEQCLTDCAPGFSYQNLDKTKCCGKCVQTSCIFEQKLYEVNALWKSADNCTTYSCLKKDGQFLVTTSREVCPDVGSCLSHLLYQDGCCKRCK-------------------SEPLVEDKSSCLPVSLAESRTKEILKFPVQGHGTCVNADPIQGFTDCEGACSSGSKYNTLTDMHEKFCTCCSIKSYHPISVKMICDDGHTFT-QKHEVPSNCGCSPCSEFSDSAIDVRMQQDAQSPLLQLLGNHRH", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . . . *. . : .: .* ***.*: *:* * : . : **: * :** : :***** : . . *: *: . . .. . : *:: * .:* : :* : . .: :: :: . . : :: .*:: * . ****. :.*.: ** : * : * .:* : . .: . : . . *. ** : * .. . :* * * . : * .: *: ** . *. :: * : * * . *. *: * :**:**:. : . *: ***. :* . . : ::** *** * * *: * ..*...** .: :***: * * ..*.* * *::.:. : .: . * :* ::*.: ::.:.. :.: :. .:: .: * . . *:. ** *: *. *: : :: *:*:: :* *******.* *****:* * *:: *.: *:. .:* .** : : : : : *. : ::* * :.* : :* *.* * *:*. *: *. * *:*: :* : **:.* :. * * * *. * ** *** ** . :.: . . ***:: * * * * .: ** : . . * ** .: *:.:. .*.. . :**: :: . *:.**.* * : . *. * *.* **.* *::: . *: * *: *.::* . * * *:.:** *: **** :*: *.*. *.*. : ::: ::* * *: * * : * : *::: *.: ..* . . :: : ::.* :.:*.. .: : **. * :::: * .*: :: *****:: :: ::*:**. :.* ** :* .* . . * :* **.:*: :*. * *::*: **. * : *: .*: ***.*.:******:*::*:***. *.*:*: : **: :** :*: . . . . :. . . : :: . . : . *.: .:. : . .. : : . .. : * .. : :*. * : ..: .:* . . : : :* : . : ::: *: * : : .* . * :: . . * .: : : . . . . .... . : : .: *. . :.: . . . . .* . ::* : .* *. . .: . .. . . . . . . .. . . * . :: . : : . . . . ::..: : :.. . : : :. . : * . : . . . .: .. .: . . : . : .. .: .. . * . . : . . :* . : : . . . ::* . *: .::.: . . *. : : : .. * :.* * . :.. .: ****. : : : .. :: . : . : : : . . ::: . : . . : .* : :.*: : :. :. *:: : .. : *** :*: :* :* :: *. * *** . . : . * :: : **: ** * * : : :. . * * :. * ..: ** * : *.. : * * . : * ** *.***: : .. .*.*.. . : . *:.* * . : :. * : * . . ...* ...*:* :*: . . : . ::. . ** :**. . : . . ::: :: .. * : :* .. : . . *::* * . ..: * *: : : : * * . :.*** * . * . ::: .* :: * . * * : **: :*: . * . *. . ** :. * : : :: .: . .:::. ** * . ..* : * : *. . .* * .* : : :***: * ** ** *:: : :. * . *:: :..*:* *.*.* ** : : :**.** . : **:: * . *:. . : *::*.*. . ", "identical_positions": 412, "similar_positions": 753, "identity": "10.47%" }, { "cls_id": "homologset.agr.MGI:1202065", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q91ZN7-1", "uniprot_id": "CHK1_RAT", "id": "Q91ZN7-1", "name": "Serine/threonine-protein kinase Chk1", "aln": "-------------MAVPFVEDWDLVQTLGEGAYGEVQ---LAVNRITEEAVAVKIVDMKRAIDCPEN--IKKEICINKMLNHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEQDAQRFFHQLMAGVVYLHGIG-ITHRDIKPENLLLDERDNLKISDFGLATVFRHN-NRERLLNKMCGTLPYVAPELLKRK-EFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKK--TYLNPWKKIDSAPLALLHKILVENPSARITIPDIKKDRWYNKPLNRGAKRPRATSGGMSESSSGFSKHIHSNLDFSPINSGSSEENVKFSSSQPEPRTG-------LSLWDTG--------PSNVDKLVQGISFSQPTCPDHMLVNSQLLGTPGSSQNPWQRLVKR--------MTRFFTKLDADKSYQCLKETFEKLG-----------------YQWKKSCMNQVTVSTMDRRNNKLIFKINLVEMDEKIL-VDFRLSKGDGLEFKRHFLKIKGKLSDIVSSQKVWFPVT-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35280-1", "uniprot_id": "CHK1_MOUSE", "id": "O35280-1", "name": "Serine/threonine-protein kinase Chk1", "aln": "-------------MAVPFVEDWDLVQTLGEGAYGEVQ---LAVNRITEEAVAVKIVDMKRAIDCPEN--IKKEICINKMLSHENVVKFYGHRREGHIQYLFLEYCSGGELFDRIEPDIGMPEQDAQRFFHQLMAGVVYLHGIG-ITHRDIKPENLLLDERDNLKISDFGLATVFRHN-NRERLLNKMCGTLPYVAPELLKRK-EFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKK--TYLNPWKKIDSAPLALLHKILVETPSARITIPDIKKDRWYNKPLNRGAKRPRATSGGMSESSSGFSKHIHSNLDFSPVNNGSSEETVKFSSSQPEPRTG-------LSLWDTG--------PSNVDKLVQGISFSQPTCPEHMLVNSQLLGTPGSSQNPWQRLVKR--------MTRFFTKLDADKSYQCLKETFEKLG-----------------YQWKKSCMNQVTVSTTDRRNNKLIFKINLVEMDEKIL-VDFRLSKGDGLEFKRHFLKIKGKLSDVVSSQKVWFPVT-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14757-1", "uniprot_id": "CHK1_HUMAN", "id": "O14757-1", "name": "Serine/threonine-protein kinase Chk1", "aln": "-------------MAVPFVEDWDLVQTLGEGAYGEVQ---LAVNRVTEEAVAVKIVDMKRAVDCPEN--IKKEICINKMLNHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLHGIG-ITHRDIKPENLLLDERDNLKISDFGLATVFRYN-NRERLLNKMCGTLPYVAPELLKRR-EFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKK--TYLNPWKKIDSAPLALLHKILVENPSARITIPDIKKDRWYNKPLKKGAKRPRVTSGGVSESPSGFSKHIQSNLDFSPVNSASSEENVKYSSSQPEPRTG-------LSLWDTS--------PSYIDKLVQGISFSQPTCPDHMLLNSQLLGTPGSSQNPWQRLVKR--------MTRFFTKLDADKSYQCLKETCEKLG-----------------YQWKKSCMNQVTISTTDRRNNKLIFKVNLLEMDDKIL-VDFRLSKGDGLEFKRHFLKIKGKLIDIVSSQKIWLPAT-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PQA7-1", "uniprot_id": "A0A8M9PQA7_DANRE", "id": "A0A8M9PQA7-1", "name": "Serine/threonine-protein kinase CHK1", "aln": "-------------MAVPFVKDWDVVQTLGEGAYGEVR---LLVNKKTEEAVAVKVVDMAKAKDCIEN--VKKEVCICKMLSHPNIVRFFGHRSEGTTQYIFLEYCSGGELFDRIEPDVGMPEKEAHRFFQQLIAGVEYLHSVG-ITHRDIKPENILLDDKDNLKISDFGLATMFRHR-GRERALNRLCGTLPYVAPELMSRS-SFNAQPADTWACGIVLTAMLAGELPWDQPSENCQEYLDWLERK--TYLTPWKKIDAVPLSLLSKILLHNPEDRFTIPEIKKHRWFSRSFKSAVQRQGITPAAKIQRAD------------SELRRKNSDDRAQISSSQPEPQG----------LWEEK--------EVTVHTDVS-VSFSQPTCPDHMLLGTQLLGTPGASQSPWQRLVRR--------MTRFFTTENTEASCIALRDSCIALG-----------------HTWKQSCNNQATVSTMDRRNNKLIFIVHFLEMEERIL-VDFRLSKGDGLEFKRIFLKLKQKLSDIISNQKVLPLI--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O61661-1", "uniprot_id": "CHK1_DROME", "id": "O61661-1", "name": "Serine/threonine-protein kinase grp", "aln": "MAATLTEAGTGPAATREFVEGWTLAQTLGEGAYGEVK---LLINRQTGEAVAMKMVDLKKHPDAANS--VRKEVCIQKMLQDKHILRFFGKRSQGSVEYIFLEYAAGGELFDRIEPDVGMPQHEAQRYFTQLLSGLNYLHQRG-IAHRDLKPENLLLDEHDNVKISDFGMATMFRCK-GKERLLDKRCGTLPYVAPEVLQK--AYHAQPADLWSCGVILVTMLAGELPWDQPSTNCTEFTNWRDNDHWQLQTPWSKLDTLAISLLRKLLATSPGTRLTLEKTLDHKWCNMQFADNERSYDLVDSAAALEICSPKAKRQRLQSSAHLSNGLDDSISRNYCSQPMPTMRSDDDFN-VRLGSGRSKEDGGDRQTLAQEARLSYSFSQPALLDDLLLATQMNQTQNASQNYFQRLVRR--------MTRFFVTTRWDDTIKRLVGTIERLGG----------------YTCKFGDDGVVTVSTVDRNKLRLVFKAHIIEMDGKIL-VDCRLSKGCGLEFKRRFIKIKNALEDIVLKGPTTWPIAIATNSVP", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38147-1", "uniprot_id": "CHK1_YEAST", "id": "P38147-1", "name": "Serine/threonine-protein kinase CHK1", "aln": "-------MSLSQVSPLPHIKDVVLGDTVGQGAFACVKNAHLQMDPSIILAVKFIHVPTCKKMGLSDKDITKEVVLQSKCSKHPNVLRLIDCNVSKEYMWIILEMADGGDLFDKIEPDVGVDSDVAQFYFQQLVSAINYLHVECGVAHRDIKPENILLDKNGNLKLADFGLASQFRRKDGTLRVSMDQRGSPPYMAPEVLYSEEGYYADRTDIWSIGILLFVLLTGQTPWELPSLENEDFVFFIENDGNLNWGPWSKIEFTHLNLLRKILQPDPNKRVTLKALKLHPWVLRRASFSGDDGLCNDPELLAKKLFSHLKVSLSNENYLKFTQDTNSNNRYISTQPIGNELAELEHDSMHFQTVSNTQRAFTSYDSNTNYNSGTGMTQEAKWTQFISYDIAALQFHSDENDCNELVKRHLQFNPNKLTKFYTLQPMDVLLPILEKALNLSQIRVKPDLFANFERLCELLGYDNVFPLIINIKTKSNGGYQLCGSISIIKIEEELKSVGFERKTGDPLEWRRLFKKISTICRDIILIPN-------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .::. : :*:*:**:. *: * :: ** . * : . :. :: : * .. ::::: . . . :::** . **:***:****:*: . *: :* **::.: *** ::***:****:***...*:*::***:*: ** . . * *: **:***:: : *: .* *: *::* .:*:*: **: ** . :: : :.. **.*:: : ** *:* * *.*: . * :. : .:** : .::* : .:: :.:. :.**:* :*:*:. : * : . .:.* .. :* ::::: .: *. . ..* **::* * *:. *:: ", "identical_positions": 95, "similar_positions": 141, "identity": "17.37%" }, { "cls_id": "homologset.agr.MGI:1202066", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P60059-1", "uniprot_id": "SC61G_HUMAN", "id": "P60059-1", "name": "Protein transport protein Sec61 subunit gamma", "aln": "--------------MDQVMQFVEPSRQFVKDSIRLVKRCTKPDRKEFQKIAMATAIGFAIMGFIGFFVKLIHIPINNIIVGG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P60060-1", "uniprot_id": "SC61G_MOUSE", "id": "P60060-1", "name": "Protein transport protein Sec61 subunit gamma", "aln": "--------------MDQVMQFVEPSRQFVKDSIRLVKRCTKPDRKEFQKIAMATAIGFAIMGFIGFFVKLIHIPINNIIVGG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F2Z4R1-1", "uniprot_id": "F2Z4R1_DANRE", "id": "F2Z4R1-1", "name": "Protein transport protein Sec61 subunit gamma", "aln": "--------------MDQVMQFVEPSRQFVKDSIRLVKRCTKPDRKEFQKIAMATAIGFAIMGFIGFFVKLIHIPINNIIVGG", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8I6AAZ9-1", "uniprot_id": "A0A8I6AAZ9_RAT", "id": "A0A8I6AAZ9-1", "name": "Protein transport protein Sec61 subunit gamma", "aln": "--------------VDQVMQFVEPSRQFVKDSIRLVKRCTKPDRKEFQKIAMATAIGFPIMGFIGFFVKLIHIPINKIIVGG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A0G2K7E7-1", "uniprot_id": "A0A0G2K7E7_RAT", "id": "A0A0G2K7E7-1", "name": "Protein transport protein Sec61 subunit gamma", "aln": "--------------MDQVMLFVEPSRQFVKASILLVKGCSKPDRKKFQKIAVATAIGFAIMGFIGFFVKLIHIPINNIIVGG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VWE9-1", "uniprot_id": "S61G2_DROME", "id": "Q9VWE9-1", "name": "Protein transport protein Sec61 gamma-2 subunit", "aln": "--------------MDKVVKFAEPGRAFAKDSIRLVKRCTKPDRKEFQKIAIATAVGFCIMGFIGFFVKLIHIPINNIIVGS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V668-1", "uniprot_id": "S61G1_DROME", "id": "Q9V668-1", "name": "Protein transport protein Sec61 gamma-1 subunit", "aln": "--------------MDKVVKFAEPGRAFAKDSIRLVKRCTKPDRKEFQKIAIATAVGFAIMGFIGFFVKLIHIPINNIIVGS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P35179-1", "uniprot_id": "SC61G_YEAST", "id": "P35179-1", "name": "Protein transport protein SSS1", "aln": "MARASEKGEEKKQSNNQVEKLVEAPVEFVREGTQFLAKCKKPDLKEYTKIVKAVGIGFIAVGIIGYAIKLIHIPIRYVIV--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::* :.*. *.: . :: *.*** *:: **. *..:** :*:**: :*******. :** ", "identical_positions": 25, "similar_positions": 23, "identity": "30.49%" }, { "cls_id": "homologset.agr.MGI:1202069", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O14519-1", "uniprot_id": "CDKA1_HUMAN", "id": "O14519-1", "name": "Cyclin-dependent kinase 2-associated protein 1", "aln": "------------------------------------------------------------------------------------------------------------------MSYKPN-----------------LAAHMPAAALNAAGSVHS-----------PSTSMATSSQYRQL-LS----DYGPPSLG----YTQGTGNSQVPQS---------------KYAELLAIIEELGKEIRPTYAGSKSAMERLKRGIIHARGLVRECLAETERNARS--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O35207-1", "uniprot_id": "CDKA1_MOUSE", "id": "O35207-1", "name": "Cyclin-dependent kinase 2-associated protein 1", "aln": "------------------------------------------------------------------------------------------------------------------MSYKPN-----------------LTAHMPAAALN-AGSVHS-----------PSTSMATSSQYRQL-LS----DYGPPSLG----YTQGTGNSQVPQS---------------KYAELLAIIEELGKEIRPTYAGSKSAMERLKRGIIHARSLVRECLAETERNARS--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "M9PEA2-1", "uniprot_id": "M9PEA2_DROME", "id": "M9PEA2-1", "name": "", "aln": "MDIMDIQAVESKLSDVTVTPIPRSQVQNFYNYQQQREQREQQPQIQISAIHHSRGSVGGGGGSNSSNAATDYSTSSGGKRERDRSSASDYSSSSSKQSSAAAANAAAAAAAVAALQYSPQFLQAQLALLQQQSNTTATPAAVAAAALSLANMCSSNGGQRNSGAGVSSTSSGSNGQSMGLNLSSSQLKYPPPSTSPVVVTTQTSANITTPLTSTASLPSVGPGNGLTKYAQLLAVIEEMGRDIRPTYTGSRSSTERLKRGIVHARILVRECLMETERAARQXEEESLAPQLATPE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.*.*: .* :.****. *. * .*** .:..* * ** .* *** . ** :.* .* : ***:***:***:*::*****:**:*: *******:*** ****** **** **. ", "identical_positions": 64, "similar_positions": 30, "identity": "21.69%" }, { "cls_id": "homologset.agr.MGI:1202070", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P47759-1", "uniprot_id": "NSG2_MOUSE", "id": "P47759-1", "name": "Neuronal vesicle trafficking-associated protein 2", "aln": "MVKLNSNPGEKGAKPPSVEDGFQTVPLITPLEVNHLQLAAPEKVIVKTRTEYQPEQRNKGKFRVPKIAEFTVTILVSLALAFLACIVFLVVYKAFTYDHSCPEGFVYKHKRCIPASLDAYYSSQDPSSRSRFYTVISHYSVAKQSTARAIGPWLSAAAVIHEPKPPKTQGH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q3KR51-1", "uniprot_id": "NSG2_RAT", "id": "Q3KR51-1", "name": "Neuronal vesicle trafficking-associated protein 2", "aln": "MVKLNGNPGEKGAKPPSVEDGFQTVPLITPLEVNHLQLSAPEKVIVKTRTEYQPEQRNKGKFRVPKIAEFTVTILVSLALAFLACIVFLVVYKAFTYDHSCPEGFVYKHKRCIPASLDAYYSSQDPSSRSRFYTVISHYSVAKQSTARAIGPWLSAAAVIHEPKPPKTQGH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y328-1", "uniprot_id": "NSG2_HUMAN", "id": "Q9Y328-1", "name": "Neuronal vesicle trafficking-associated protein 2", "aln": "MVKLNSNPSEKGTKPPSVEDGFQTVPLITPLEVNHLQLPAPEKVIVKTRTEYQPEQKNKGKFRVPKIAEFTVTILVSLALAFLACIVFLVVYKAFTYDHSCPEGFVYKHKRCIPASLDAYYSSQDPNSRSRFYTVISHYSVAKQSTARAIGPWLSAAAVIHEPKPPKTQGH", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*****.**.***:*************************.*****************:*********************************************************************.********************************************", "identical_positions": 165, "similar_positions": 6, "identity": "96.49%" }, { "cls_id": "homologset.agr.MGI:1202294", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LJN0-1", "uniprot_id": "A0ABK0LJN0_RAT", "id": "A0ABK0LJN0-1", "name": "", "aln": "-MDL--FDFFRDWDLEQQCHYEQDRSALKKREWERRSQEVQQEEDLFSSGFDLFGEPYKVAEYTNKGDALANRVQNTLGS---------YDEMKDLLSNHSSQNHLVGIPKNSVPQTPISK-SEASLYPEQKN-RMIPSHQENTHSSVPMPPPSVVILNSTLIN---SNRKSKSEWPRDNHNTSPGQACQASSQPNKIQTSTQDPPQTRLEDFFVYPAEQPQIGTAEKSNPSAKEDNNPNSGGEDAFKEIFQ---SNSPEESEFTVQAPGSPLVAS--------SLLAPSSGLSVPTFPPG-------------LYCK-TSMGQQKPTAYVRP-------------MDGQDQATDISPT-------------LKPSIEFENSFGNLSFGSLLDGKPSAASTKNKLPKFTILQTSEVSLTSEPSCVEEILRE-----------------------------------SQHLTPGFTLQKWSDPSSRASTKSVPLKSMLEDDLKLSSDEDDLEPVKTLTTQCTANELYQAVEKAKPKNNPVNSLLATPQPTS--AAQASVGSGSSSESESSSESDSDTESSTTDSESNEAPRVATPEPEPPSTNKWQLDKWLNKVTSQNKS------------------------------------------FICGQNETPTETISLP-PPIIQPVEVQVKVKPNPSQSVAVPKERPLLSLIREKARPRPTQKTPETKALKHKLSTSVDSVS--------------------------QRTIGKKQPKKVEKNTSFEEFIWPKPNTTSSTPKEKESVELPDPPRSRN---KATAHKPVPRKEPRP--------HVPLATEKKKYRGPGK---------------------------------------IVPKSREFIETDSSTSDSSTDQEETLQIKVLPP----------CIAPGGNTSKSKETSNASLTLSTLTSSNSNNNSN-NLSTSNEETAFSPPPAMQTELLTPVHDHEIPKNLWVKIDLDLLSRVPGQNSVPAAPAKTDHHKETASKPKRQ-----TAAITVEKPAPKGKRKHKPAEAAEKIPEKKQ-----------------------RLED-TTICLLPPCISPAPPHKPPNTREN-SSRRANRKREEKLFPPALS------------------------------------------------------------------------PLAEDP-----------------------PRRRNVSGNNGFFSQDKNISMAGQITSTKPKRSEGKFCATFKGISISEGDAPKKPASATVTVANTAIATA--------------------TATATAPAIVTATVTATATTTATATTTTTTTTISSITPTITSGLMDSSHLEMTSWAALPLLASSSTNVR----RPKLTFDDSVHNADFYMQEAKKLKHKADALFEKFGKAVNYADAALSFTECGNAMERDPLEAKSPYTMYSETVELLRYAMR-----LKNFASPLASDGDKKLAVLCYRCLSLLYLRMFKLKKDHAMKYSRSLMEYFKQNASKVPQIPSPWVGNGKNT--PSPVSLNN--VSPINSMG-----NCNNGPVTIPQRIHHMAASHVNITSNVLRGYEHWDMADKLTRD--NKEFFGDLDTLMGPLTQHSSMTNLVRYVRQGLCWLRIDAHLL-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O55112-1", "uniprot_id": "AFF2_MOUSE", "id": "O55112-1", "name": "AF4/FMR2 family member 2", "aln": "-MDL--FDFFRDWDLEQQCHYEQDRSALKKREWERRNQEVQQEEDLFSSGFDLFGEPYKVAEYTNKGDALANRVQNTLGS---------YDEMKDLLSNHSSQNHLVGIPKNSAPQTPISK-SEASFYPEQKN-RMIPSHQETTHSSTPMPPPSVVILNSTLIH---SNRKSKSEWPRDSHNTSPAQASQTSSQPNKMQTSTQDPPQTRLEDFFVYPAEQPQIGTVEKSNPSSKEENNPNSGGEDTFKEIFQ---SNSPEESEFTVQAPGSPLVAS--------SLLAPSSGLSVPTFPPG-------------LYCK-TSMGQQKPTAYVRP-------------MDGQDQATDISPT-------------LKPSIEFENSFGNLSFGSLLDGKPSAVSSKTKLPKFTILQTSEVSLTSDPSCVEEILRE-----------------------------------SQHLTPGFTLQKWSDPSSRASTK------MLEDDLKLSSDEDDLEPVKTLTTQCTANELYQAVEKAKPKNNPVNPLLATPQSTP--ATQTNVGSGSSSESESSSESDSDTESSTTDSESNEAPRVATPEPEPPSTNKWQLDKWLNKVTSQNKS------------------------------------------FICGQNETPTETISLP-PPIIQPVEVQVKVKPNPSQAVAVPKERPLLSLIREKARPRPTQKTPETKALKHKLSTSVDTVS--------------------------QRTIGKKQPKKVEKNTSFEEFTWPKPNITNSTPKEKGSVELPDPPRSRN---KATAHKPVPRKEPRP--------HVPLATEKKKYRGPGK---------------------------------------IVPKSREFIETDSSTSDSNTDQEETLQIKVLPP----------CIT-----SKSKETSNASLTLSTLT----NGNSN-NLSTSNEETAFSPPPAMQTELLSPLRDHENPKNLWVKIDLDLLSRVPGQNSVPVTPAKTD-YKETASKPKRQ-----TAATAVEKPAPKGKRKHKPAETAEKIPEKKQ-----------------------RLEDNTTICLLPPCISPAPPHKPPSTREN-SSRRANRKKEEKLFPPALS------------------------------------------------------------------------PLAEDP-----------------------PRRRNVSGNNGHFGQDKNISMAGQITSSKPKRSEGKFCATFKGISINEGDAPKKAASATVTVANMALATA--------------------TATATVPAIVTATVTATATTTATATTTTTTTTISSITPTITSGLMDSSHLEMTSWAALPLLSSSSANVR----RPKLTFDDSVHNADFYMQEAKKLKHKADALFEKFGKAVNYADAALSFTECGNAMERDPLEAKSPYTMYSETVELLRYAMR-----LKNFASPLASDGDKKLAVLCYRCLSLLYLRMFKLKKDHAMKYSRSLMEYFKQNASKVTQIPSPWVGNGKNT--PSPVSLNN--VSPINSVG-----NCNNGPVTIPQRIHHMAASHVNITSNVLRGYEHWDMADKLTRD--NKEFFGDLDTLMGPLTQHSSMTNLVRYVRQGLCWLRIDAHLL-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P51816-1", "uniprot_id": "AFF2_HUMAN", "id": "P51816-1", "name": "AF4/FMR2 family member 2", "aln": "-MDL--FDFFRDWDLEQQCHYEQDRSALKKREWERRNQEVQQEDDLFSSGFDLFGEPYKVAEYTNKGDALANRVQNTLGN---------YDEMKNLLTNHSNQNHLVGIPKNSVPQNPNNK-NEPSFFPEQKN-RIIPPHQDNTHPSAPMPPPSVVILNSTLIH---SNRKSKPEWSRDSHNPSTVLASQASGQPNKMQTLTQDQSQAKLEDFFVYPAEQPQIGEVEESNPSAKEDSNPNSSGEDAFKEIFQ---SNSPEESEFAVQAPGSPLVAS--------SLLAPSSGLSVQNFPPG-------------LYCK-TSMGQQKPTAYVRP-------------MDGQDQAPDISPT-------------LKPSIEFENSFGNLSFGTLLDGKPSAASSKTKLPKFTILQTSEVSLPSDPSCVEEILREMTHSWPTPLTSMH------TAGHSEQSTFSIPGQESQHLTPGFTLQKWNDPTTRASTKSVSFKSMLEDDLKLSSDEDDLEPVKTLTTQCTATELYQAVEKAKPRNNPVNPPLATPQPPP--AVQASGGSGSSSESESSSESDSDTESSTTDSESNEAPRVATPEPEPPSTNKWQLDKWLNKVTSQNKS------------------------------------------FICGQNETPMETISLP-PPIIQPMEVQMKVKTNASQVPAEPKERPLLSLIREKARPRPTQKIPETKALKHKLSTTSETVS--------------------------QRTIGKKQPKKVEKNTSTDEFTWPKPNITSSTPKEKESVELHDPPRGRN---KATAHKPAPRKEPRP--------NIPLAPEKKKYRGPGK---------------------------------------IVPKSREFIETDSSTSDSNTDQEETLQIKVLPP----------CIISGGNTAKSKEICGASLTLSTLMS--SSGSNN-NLSISNEEPTFSPIPVMQTEILSPLRDHENLKNLWVKIDLDLLSRVPGHSSLHAAPAKPD-HKETATKPKRQ-----TAVTAVEKPAPKGKRKHKPIEVAEKIPEKKQ-----------------------RLEEATTICLLPPCISPAPPHKPPNTRENNSSRRANRRKEEKLFPPPLS------------------------------------------------------------------------PLPEDP-----------------------PRRRNVSGNNGPFGQDKNIAMTGQITSTKPKRTEGKFCATFKGISVNEGDTPKKASSATITVTNTAIATA--------------------TVTATA--IVTTTVTATAT--ATATTTTTTTTISTITSTITTGLMDSSHLEMTSWAALPLLSSSSTNVR----RPKLTFDDSVHNADYYMQEAKKLKHKADALFEKFGKAVNYADAALSFTECGNAMERDPLEAKSPYTMYSETVELLRYAMR-----LKNFASPLASDGDKKLAVLCYRCLSLLYLRMFKLKKDHAMKYSRSLMEYFKQNASKVAQIPSPWVSNGKNT--PSPVSLNN--VSPINAMG-----NCNNGPVTIPQRIHHMAASHVNITSNVLRGYEHWDMADKLTRE--NKEFFGDLDTLMGPLTQHSSMTNLVRYVRQGLCWLRIDAHLL-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B5H1-1", "uniprot_id": "A0ACD6B5H1_DANRE", "id": "A0ACD6B5H1-1", "name": "", "aln": "-MDLFEFDFFRDWELEQQCHYEQDRSALKKKEWERRTQEVQQDEDLFSTGFNLFGEPYK----TNKGDALANRVQNTLGN---------YDEMKELLTSHSNQSHLVGIPKNSVPQTPVEKPDQPGFFPEAQR-SRPALSQPGSHSTSMPPPPANTIPGSSVMHGHQSKKSRSSDWSQGGHRSSGVQTTQAASRG---KHSSHEQTSNRHDQDQEDSSPNP-NGPTTSSHSSRKQ---AQAGKGPATAELGL---GKSPAEQDSCSHGSSSPLAST--------SLLP--SGLSTPTFPQG-------------LHCKPSSAVQQKPTAYVRP-------------MDGQDQVPNDSPE-------------LKPPVELVEGYNTVPFGGLLDTKSSTTGTKGKIPKLTLPQSGEVSLPNDSNCVEEILREMTHSWPPPLTAIH------TPGKAEQTKFPIPSKDSQHVTSGYNAKRCSVPSNKPATKSVPQKSMLEDDLKISSDEEDND---------------QAAEKPKPRSTALNLPGSTAVRSSEAAGHSSGASGSSSESESSSESDSDSESSSSDSECNRASRAATPEPEP---SKWQLDKWIKKVNPHNKA------------------------------------------LINTQADSHGLNSSQPDESQTSENQSYSKSKPSTALAPADPKERTLLSPIREKAKPKAGQKAPDSKSTKVKSPASVELAPP-------------------------RRSTGKKQPKKVERSSSSEEHNWPRPGNSSSTPKEKEPPPLE-PPKPRG---KGPVVKTAPRKEPRTTTTSTAPTNIAPVPDKKKHRGPNK---------------------------------------IIPKSKEFIETESSSSECHSDPEE--LTKVQLP----------CPGPNTLSLKSKDCNSNILSVSSLTSTSSTSIPDPGASDLLEEHLFSPIPIVQNELLSPLRDFEDIKSLWVKIELSFLSRIPGQDPPEPPPTKAE-CREVSVKHRRQQS---PASIPAEKNPSKSKRKHKSEHCDVMSGGKKL-----------------------RLDK--DTLLLPPCISPIHNHKVSSTKDS--LKKQPRKKDDKLLPPLLS------------------------------------------------------------------------PLSVEP-----------------------VGR--------------------------PRRSSE--CSSLS----QEG--------STSTIPNNLPSSR--------------------TIPASSSSSSSSSSHKHRKGENKAFSHSKTSTEEDSHSKPSGGFHGNGQSDADLWSNPSALTMEHMEPR----RPKLTFNSTVHSADYYMQEAKKLKHKADALMDKFGKAVNYADGALSFIECGNAMERDPLEAKSPYTMYSETVELIRYAMR-----LKNFTSHSATIAEKKLAVLCNRCLSLLYLRMFKLKKDHAMKYSRSLMEYFKN-SAKSSQAPSPWGANGKSTGTPSPMSLSPSPVSSVSSSAGAMGSSSASGSVAIPQRIHHMAASHVNITNNILRSYEHWETADKLAQE--SQEFFVELDSVMEPLTQHSSMTELVRYIRQGLHWLRLEAHLL-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VQI9-1", "uniprot_id": "AFFL_DROME", "id": "Q9VQI9-1", "name": "AF4/FMR2 family member lilli", "aln": "MAQQQQQQMQQQQQHHTSSINNNNSSSIVLLQQQQPQQQQQQLDQLQQYNNNLYSQNYNMEEYERRKRREREKIERQQGIQIDDRETSLFGEPRRLTEGDAEITAALGEFFEAREYINNQTVGISRSAPGAGNPRLQPNLAPQAKSLGHSPSSASSAAGPTAASATTSLPGQQQHYQQQQRPPTYVKQADNKPPYNGRGGYPGQPMKNDIPSSSGMAPPRGPPRTSSSNSNSSSVTNNASSGGVPASTPLGPPLSTQMPNGREKSFLGPPAPALHNGTGGRFVPPAASKRPGVGQQPPPPEKDVNKIISDIANIFTVQPLTLIAATPHAPTRENYNLLAPNRQKYAMDIPSSPPSAEPSSLMTPLFAPITSPIAPLVTTPPQASQMPLGGATSGTILAGEALAPLHQLPPTMPKAASGVTSPGPVKPLKTEKNHSLEKQDSCLENDLELSESEDEQRKKEGRSGGNSSNSSESDSSESGSESSSKNDLQHHPNHQQHHHQLQQQQQQQQATMQQQQVLQQQHRSQPLTSNGAQNKKFRHEIIARGSNTITGLLSSSGFGSGGNVGPAGVNSNAVVGTGSGSGGTLSSGGSSSNKTPSPTESNKWNLSRFFHKPANQTNSESVSPGNVSMKVPGILPGGAQIIPESIDVTTAIVKNEKNDMAMEEGEEEDDDEEQQLRYGGGLSVTPVAVKKEAIDAVSEMALGAIPKTQIKRESAETLLSARLSDSGTSASGSSSSSSSSSDSAMGGEVVPMPGPGETLQLPGVPAAITTVMRVQPTQSQKAPPSNSVTLTPILPLPTSPKQRQKKPRKKKAITSAPILDSSDDDEPPPKHPGLDHTAVSVQTQPATDTVKKGRGRPRKQQQSGGSGNLSSASAGSSSQTKGPTLTAAKKPLAKTPLAMSRARKREHSSQSSSNGNTPTKKVATPQLVAAPLKPTSNTAGSSSSDEDSSSSAESSSKSSSSSSSSDDTETQNTNCRIVKLNKTGAVQKKALLGSGSSSPSSSGSEAEDQTTRSQVGSGQALAQQLPPYKQLPISQHSQHLSSSDCSSSSGGCTAVCSSSSGEEDEGRREKERERKPKSDKNKINTLTRIFNPKEGGAKKQGQVVIVDLQEEQQQGKLDAAAQPSAPQAPPAAPAAIMAKPRMTPTQQQQLGAGLASPARTTTPHLTSLICKIDLSKLSRERIMRLKKLTPAQQNGHLTPKDQATNAVHVPNGYAGDTNPAAKVKHEHPVKPEPELDAGYEAKFKPGNVKQEFQLKQERDRDRERERERERERERDREREQPPGRRRKRSSSSSSSPYKEKKRKKEKADQLQMGKELLPVPVLLPSNNHERMPNHDRLSYDKLQLLHEDAAAVIGDVSAPNGSPTKKLLAMSPLPPPPTVTVAPATCNEAVQTTPPSATATSAIAPPVPATRLIYRSYFDRDVEHPSDDPRKNNQFLQEAINRKHAADLERDSFNQVTLYLEAVVYFLLTADAMER-CSSEQATNTMYKDTLSLIKFISTKFRPYQQQSTTNIQHETHNKVAILSLRCQSLISLKLYKLRRKDCRAIINSLTDFFRVGRGDIANGNTPSSISPSNS------------VGSQGSGS------NTPPGRIVPPDIHNMLCKQNEFLSYLNSAHELWDQADRLVRTGNHIDFIRELDHENGPLTLHSTMHEVFRYVQAGLKTLRDAVSHPTHQSQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: :: : . .. ::: *:: : :: *: ** ::* . . :*:.: *: .: ::::. * :.* : * ..:. . :* :: .. . . * . . ::. *..: ..: * . .: : : .: : . : . . .. . .. * . ..:. : : : * : .. :* . . . .*:. * : : : .* * .* ** .. .. .* : * : . :.:* . . : : : ::. . .* .... *: : * *.: : . . : . .:.: : ..:*: ..:::: : : .: :. : . . :. .**.. . . ... .* :.. . . :. *.* .**:*.::::* :.:: : : : . . * :. : . . **.*.. : .:: : .:: . . : : **.: :: .. :. . ::**:: . ... . * *.* . . ** ** : :.:::: .:..*:*: : :: :: . . .* : . : *: . : : .. . : . :* . . :. .: ::. . :. : . . .: :. : . . .* . .. . *:.* . :* *:. * .. .* : . : : ::: : . *: *: :* :*:. .:. . .: .: .*: ::. . . . ..* .. . .. . : . :. * * .. :. : ::*** : ** ** :.*.:.. * :..: * .:**** . ::. ***.:*:.*::: :: :: .:*:*:*. ** **: *:::**::... .** ::*: .. .: :* . ..: *.. .: . :* **:* ..: :: . : .:* *: **:*.: :*: :** *** **:* ::.**:: ** ** . ", "identical_positions": 134, "similar_positions": 439, "identity": "7.92%" }, { "cls_id": "homologset.agr.MGI:1202295", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3U0P5-1", "uniprot_id": "ENTP6_MOUSE", "id": "Q3U0P5-1", "name": "Ectonucleoside triphosphate diphosphohydrolase 6", "aln": "-----------------------------MRKIPNHGTLRMTKVAYPLGLCVGLFIY-----------------------------VAYIKWHRASAAQAFFTIAGAASG----------ARWTQQAFSSPGSAARGHEVFYGIMFDAGSTGTRIHVFQFARPPGE-TPTLTHETFKALKPGLSAYADDVEKSAQGIQELLNVAKQHIPYDFWKATPLVLKATAGLRLLPGEKAQKLLQKVKEVFKASP--FLVGDDCVSIMNGTDEGVSAWITVNFLTG--SLKTPGSSSVGMLDLGGGSTQITFLPRVEGTLQASPPGHLTALQMFNRTYKLYSYSYLGLGLMSARLAILGGVEGKPAEND----------KELVSPCLSPRFRG--------EWEHAEVTYRISG--------QKAVG-LYELCASRVSEVLRNKVHRT----EEAQHVDFYAFSYYYDLAASFGLIDAEKG------GSLVVGDFEIAAKYVCRTL--ETQPPSSPFACMDLTYISLLLHE-FGFPGDKVLKLARKIDNVETSWALGAIFHYIDSLKRQKVPAL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9ER31-1", "uniprot_id": "ENTP6_RAT", "id": "Q9ER31-1", "name": "Ectonucleoside triphosphate diphosphohydrolase 6", "aln": "-----------------------------MRKIPNHGTLRMTKVAYPLGLCVGLFIY-----------------------------VAYIKWHRASAAQAFFTIAGAASG----------VRWTQQAFSSPDSATRGHEVFYGIMFDAGSTGTRIHVFQFARPPGE-TPTLTHETFKALKPGLSAYADDVEKSAQGIQELLNVAKQHIPYDFWKATPLVLKATAGLRLLPGEKAQKLLQKVKEVFKASP--FLVGDDCVSIMNGTDEGVSAWITVNFLTG--SLKTPGSSSVGMLDLGGGSTQITFLPRVEGTLQASPPGHLTALQMFNRTFKLYSYSYLGLGLMSARLAILGGVEGKPAEDD----------KELVSPCLSPRFRG--------KWEHAEVTYRISG--------QKAVG-LYELCASRVSEVLRNKVHRT----EEAQHVDFYAFSYYYDLAASFGLIDAEKG------GSLVVGDFEIAAKYVCRTL--ETQPPSSPFACMDLTYISLLLHE-FGFPGDKVLKLARKIDNVETSWALGAIFHYIDSLKRQKVPAL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75354-1", "uniprot_id": "ENTP6_HUMAN", "id": "O75354-1", "name": "Ectonucleoside triphosphate diphosphohydrolase 6", "aln": "-MKKGIRYETSRKTSYIFQQPQHGPWQTRMRKISNHGSLRVAKVAYPLGLCVGVFIY-----------------------------VAYIKWHRATATQAFFSITRAAPG----------ARWGQQAHSPLGTAADGHEVFYGIMFDAGSTGTRVHVFQFTRPPRE-TPTLTHETFKALKPGLSAYADDVEKSAQGIRELLDVAKQDIPFDFWKATPLVLKATAGLRLLPGEKAQKLLQKVKKVFKASP--FLVGDDCVSIMNGTDEGVSAWITINFLTG--SLKTPGGSSVGMLDLGGGSTQIAFLPRVEGTLQASPPGYLTALRMFNRTYKLYSYSYLGLGLMSARLAILGGVEGQPAKDG----------KELVSPCLSPSFKG--------EWEHAEVTYRVSG--------QKAAASLHELCAARVSEVLQNRVHRT----EEVKHVDFYAFSYYYDLAAGVGLIDAEKG------GSLVVGDFEIAAKYVCRTL--ETQPQSSPFSCMDLTYVSLLLQE-FGFPRSKVLKLTRKIDNVETSWALGAIFHYIDSLNRQKSPAS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "M9PBV2-1", "uniprot_id": "M9PBV2_DROME", "id": "M9PBV2-1", "name": "nucleoside diphosphate phosphatase", "aln": "MTNTDVRKRKLATDEKPPRRKSSGSPNASSGGNRGPSGLKISFLCLIISVILLLFVFGVYHLYYVKDEVPKVVLTKTSDFPTVTVPYAHVEPHFAPPVRRVITKKPIANKPTTDNDAGFVSENASPYLARLASKFGYSKVQYAAIIDAGSTGSRVLAYKFNRSFIDNKLVLYEELFKERKPGLSSFADNPAEGAHSIKLLLDEARAFIPKEHWSSTPLVLKATAGLRLLPASKAENILNAVRDLFAKSE--FSVDMDAVEIMDGTDEGIFSWFTVNFLLG--RLSKTN--QAAALDLGGGSTQVTFSP-TDPDQVPVYDKYMHEVVTSSKKINVFTHSYLGLGLMAARHAVFTHG---YKKED----------TVLESVCVNPIIANR-------TWTYGNVQYKVSGKENGKSSAEQPIVDFDACLELVKSKVMPLVKPKP----FTLKQHAVAAFSYYFERAIESGLVDPLAG------GETTVEAYRKKAQEICAIP--NDE---QPFMCFDLTFISTLLREGFGLNDGKKIKLYKKIDGHEISWALGCAYNVLTSDEKFSNS---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32621-1", "uniprot_id": "GDA1_YEAST", "id": "P32621-1", "name": "Guanosine-diphosphatase", "aln": "----------MAPIFRNYRFAIGAFAVIMLILLIKTSSIGPPSIARTVTPNASIPKT-----------------------------PEDISILPVNDEPGYLQDSKTEQN----------YPELADAVKSQTSQTCSEEHKYVIMIDAGSTGSRVHIYKFDVCTSP--PTLLDEKFDMLEPGLSSFDTDSVGAANSLDPLLKVAMNYVPIKARSCTPVAVKATAGLRLLGDAKSSKILSAVRDHLEKDYPFPVVEGDGVSIMGGDEEGVFAWITTNYLLGNIGANGPKLPTAAVFDLGGGSTQIVFEPTFPINEKMVDGEHKFDLKFGDENYTLYQFSHLGYGLKEGRNKVNSVLVENALKDGKILKGDNTKTHQLSSPCLPPKVNATNEKVTLESKETYTIDFIGPDEPSGAQCRFLTDEILNKDAQCQSPPCSFNGVHQPSLVRTFKESNDIYIFSYFYDRTRPLGMPLSFTLNELNDLARIVCKGEETWNSVFSGIAGSLDELESDSHFCLDLSFQVSLLHTGYDIPLQRELRTGKKIANKEIGWCLGASLPLLKADNWKCKIQSA", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . :. : : :. . : : : * ::******:*: ::* .* .* *. :****:: : .*:.: **. * :* . ..**:.:********* *:.::*. *:. : . * * *.**.* :**: :*:* *:* * . . .. :********:.* * : : ... .:: .*:** ** .* : ::. * * *: * . : : .. . : . :. : . ***::: : *: . . . . . .. : ... *:**:: **: :.: : :: :** . * .*.**. : : : ", "identical_positions": 83, "similar_positions": 123, "identity": "14.59%" }, { "cls_id": "homologset.agr.MGI:1202296", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88307-1", "uniprot_id": "SORL_MOUSE", "id": "O88307-1", "name": "Sortilin-related receptor", "aln": "MATRSSRRESRLP-FLFALVALLPRGALGGGWTQRLHGGP-APLPQDRGFFVVQG--DPRDLRLGTHGDAPGASPAARKPLRTRRSAALQPQPIQVYGQVSLNDSHNQMVVHWAGEKSNVIVALARDSLALARPKSSDVYVSYDYGKSFSKISEKLNFG-VGNNSEAVISQFYHSPADNKR-YIFVDAYAQYLWITFDFCSTIHGFSIPFRAADLLLHSKASNLLLGFDRSHPNKQLWKSDDFGQTWIMIQEHVKSFSWGIDPYDQPNAIYIERHEPFGFSTVLRSTDFFQSRENQEVILEEVRDFQLRDKYMFATKVVHLPGSQQQSSVQLWVSFGRKPMRAAQFVTKHPINEYYIADAAEDQVFVCVSHSNNSTNLYISEAEGLKFSLSLENVLYYSPGGAGSDTLVRYFANEPFADFHRVEGLQGVYIATLINGSMNEENMRSVITFDKGGTWEFLQAPAFTGYGEKINCELSQGCSLHLAQRLSQLLNLQLRRMPILSKESAPGLIIATGSVGKNLAS---KTNVYISSSAGARWREALPGPHYYTWGDHGGIIMAIAQGMETN-----ELKYSTNEGETWKTFVFS--EKPVFVYGLLTEPGEKS-TVFTIFGSNKESVHSW--------LILQVNATDALG-VPCTENDYKLWSPSDERGNECLLGHKTVFKRRTPHATCFNGEDFDRPVVVSN--CSCTREDYECDFGFKMSEDLSLEVCVPDPEFSGKPYSPPVPCPVGSSYRRTRGYRKISGDTCSGGDVEARLEGELVPCPLAEENEFILYAMRKSIYRYDLASGATEQLPLSGLRAAVALDFDYERNCLYWSDLALDTIQRLCLNGSTGQEVIINSGLETVEALAFEPLSQLLYWVDAGFKKIEVANPDGDFRLTIVNSSVLDRPRALVLVPQEGVMFWTDWGDLKPGIYRSYMDGSAAYRLVSEDVKWPNGISVDSQWIYWTDAYLDCIERITFSGQQRSVILDSLPHPYAIAVFKNEIYWDDWSQLSIFRASKHSRSQVEILASQLTGLMDMKVFYKGKNAGSNACVPQPCSLLCLPKANNSKSCRCPEGVASSVLPSGDLMCDCPQGYQRKNNTCVKEENTCLRNQYRCSNGNCINSIWWCDFDNDCGDMSDERNCPTTVCDADTQFRCQESGTCIPLSYKCDLEDDCGDNSDESHCEMHQCRSDEFNCSSGMCIRSSWVCDGDNDCRDWSDEANCTAIYHTCEASNFQCHNGHCIPQRWACDGDADCQDGSDEDPVSCEK-KCNGFHCPNGTCIPSSKHCDGLRDCPDGSDEQHCEPFCTRFMDFVCKNRQQCLFHSMVCDGIVQCRDGSDEDAAFAGCSQDPEFHKECDEFGFQCQNGVCISLIWKCDGMDDCGDYSDEANCENPTEAPNCSRYFQFHCENGHCIPNRWKCDRENDCGDWSDEKDCGDSHVLPSPTPGPSTCLPNYFHCSSGACVMGTWVCDGYRDCADGSDEEACPSLAN-STAASTPTQFGQCDRFEFECHQPKKCIPNWKRCDGHQDCQDGQDEANCPTHSTLTCTSREFKCEDGEACIVLSERCDGFLDCSDESDEKACSDELTVYKVQNLQWTADFSGDVTLTWMRPKKMPSASCVYNVYYRVVGESIWKTLETHSNKTSTVLKVLKPDTTYQVKVQVHCLNKVHNTNDFVTLRTPEGLPDAPRNLQLSLNSEEEGVILGHWAPPVHTHGLIREYIVEYSRSGSKMWASQRAASNSTEIKNLLLNALYTVRVAAVTSRGIGNWSDSKSITTIKGKVIQAPNIHIDSYDENSLSFTLTMDGDIKVNGYVVNLFWSFDAHKQEKKTLSFRGGSALSHRVSNLTAHTSYEISAWAKTDLGDSPLAFEHILTRGSSPPAPSLKAKAINQTAVECIWTGPKNVVYGIFYATSFLDLYRNPKSVTTSLHNKTVIVSKDEQYLFLVRVLIPYQGPSSDYVVVKMIPDSRLPPRHLHAVHIGKTSALIKWESPYDSPDQDLFYAIAVKDLIRKTDRSYKVRSRNSTVEYSLSKLEPGGKYHIIVQLGNMSKDSSIKITTVSLSAPDALKIITENDHVLLFWKSLALKEKQFNETRGYEIHMSDSAVNLTAYLGNTTDNFFKVSNLKMGHNYTFTVQARCLFGSQICGEPAVLLYDELS--SGADAAVIQAARSTDVAAVVVPILFLILLSLGVGFAILYTKHRRLQSSFSAFANSHYSSRLGSAIFSSGDDLGEDDEDAPMITGFSDDVPMVIA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0DSP1-1", "uniprot_id": "SORL_RAT", "id": "P0DSP1-1", "name": "Sortilin-related receptor", "aln": "MATRSSRRESRLP-FLFTLVALLPPGALGGGWTQRLHGGG-APLPQDRGFFVVQG--DPHELRLGTHGDAWGASPAARKPLRTRRSAALQPQPIQVYGQVSLNDSHNQMVVHWAGEKSNVIVALARDSLALTRPKSSDVYVSYDYGKSFNKISEKLNFG-VGNSSEAVISQFYHSPADNKR-YIFVDAYARYLWITFDFGSTIHGFSIPFRAADLLLHSKASNLLLGFDSSHPNKQLWKSDDFGQTWIMIQEHVKSFSWGIDPYDQPNTIYIERHEPFGFSTVFRSTDFFQSRENQEVILEEVRDFQLRDKYLFATKVVHLPGSQQQSSVQLWVSFGRKPMRAAQFVTKHPINEYYIADASEDQVFVCVSHSNNSTNLYISEAEGLKFSLSLENVLYYSPGGAGSDTLVRYFANEPFADFHRVEGLQGVYIATLINGSMSEENMRSVITFDKGGTWEFLQAPAFTGYGEKINCELSQGCSLHLAQRLSQLLNLQLRRMPILSKESAPGLIIATGSVGKNLAS---KTNVYISSSAGARWREALPGPHYYTWGDHGGIIMAIAQGMETN-----ELKYSTNEGETWKTFVFS--EKPVFVYGLLTEPGEKS-TVFTIFGSNKESVHSW--------LILQVNATDALG-VPCTENDYKLWSPSDERGNECLLGHKTVFKRRTPHATCFNGEDFDRPVVVSN--CSCTREDYECDFGFKMSEDISLEVCVPDPEFSGKPYSPPVPCPVGSSYRRTRGYRKISGDTCSGGDVEARLEGELVPCPLAEENEFILYAMRKSIYRYDLASGATEQLPLSGLRAAVALDFDYEHNCLYWSDLALDTIQRLCLNGSTGQEVIINSGLETVEALAFEPLSQLLYWVDAGFKKIEVANPDGDFRLTIVNSSVLDRPRALVLVPQEGVMFWTDWGDLKPGIYRSNMDGSAAYRLVSEDVKWPNGISVDGHWIYWTDAYLDCIERITFSGQQRSVILDNLPHPYAIAVFKNEIYWDDWSQLSIFRASKYSRSQVETLASQLTGLMDMKIFYKGKNAGSNACIPQPCSLLCLPKANNSKSCRCPEGVASSVLPSGYLMCDCPQGYERKNNTCVKEENTCLRNQYHCSNGNCINSIWWCDFDNDCGDMSDERNCPTTICDADTQFRCQESGTCIPLSYKCDLEDDCGDNSDESHCEMHQCRSDEFNCSSGMCIRSSWVCDGDNDCRDWSDEANCTAIYHTCEASNFQCHNGHCIPQRWACDGDADCQDGSDEDPISCEK-KCNGFHCPNGTCIPSSKHCDGLRDCPDGSDEQHCEPFCTRFMDFVCKNRQQCLFHSMVCDGIIQCRDGSDEDATFAGCSQDPEFHKECDEFGFQCQNGVCISLIWKCDGMDDCGDYSDEANCENPTEAPNCSRYFQFHCENGRCIPNRWKCDRENDCGDWSDEKDCGDSHIFPSPTPGPSTCLPNYFRCSSGACVMGTWVCDGYRDCADGSDEEACPSLAN-STAASTPTQLGQCDRFEFECRQPKKCIPNWKRCDGHQDCQDGQDEANCPTHSTLTCMSREFKCEDGEACIVLSERCDGFLDCSDESDEKACSDELTVYKVQNLQWIADFSGDVTLTWTRPKKMPSASCVYNVYYRVVGESIWKTLETHSNKTSTVLKVLKPDTTYQVKVQVHCLSKVHNTNDFVTLRTPEGLPDAPRNLQLSLNSEEEGVILGHWAPPVHTHGLIREYIVEYSRSGSKMWASQRAASNSTEIKNLLLNALYTVRVAAVTSRGIGNWSDSKSITTTKGKVIQAPNIHIDSYDENSLSFTLTMDGDIKVNGYVVNLFWSFDAHKQEKKTLNFRGGSSLSHKVSNLTAHTSYEVSAWAKTDLGDSPLAFEHILTRGISPPAPSLKAKAINQTAVECIWTGPKNVVYGIFYATSFLDLYRNPKSLTTSLHNKTVIVSKDEQYLFLVRVLIPYQGPSSDYVVVKMIPDSRLPPRHLHAVQIGKTSAVIKWESPYDSPDQDLFYAIAVKDLIRKTDRSYKVRSRNSTVEYSLSKLEPGGKYHIIVQLGNMSKDSSIKITTVSLSAPDALKIITENDHVLLFWKSLALKEKQFNETRGYEIHMFDSAVNLTAYLGNTTDNFFKVSNLKMGHNYTFTVQARCLFGSQICGEPAVLLYDELS--SGGDATVVQTARSTDVAAVVVPILFLILLSLGVGFAVLYTKHRRLQSSFTAFANSHYSSRLGSAIFSSGDDLGEDDEDAPMITGFSDDVPMVIA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q92673-1", "uniprot_id": "SORL_HUMAN", "id": "Q92673-1", "name": "Sortilin-related receptor", "aln": "MATRSSRRESRLP-FLFTLVALLPPGALCEVWTQRLHGGS-APLPQDRGFLVVQG--DPRELRLWARGDARGASRADEKPLRRKRSAALQPEPIKVYGQVSLNDSHNQMVVHWAGEKSNVIVALARDSLALARPKSSDVYVSYDYGKSFKKISDKLNFG-LGNRSEAVIAQFYHSPADNKR-YIFADAYAQYLWITFDFCNTLQGFSIPFRAADLLLHSKASNLLLGFDRSHPNKQLWKSDDFGQTWIMIQEHVKSFSWGIDPYDKPNTIYIERHEPSGYSTVFRSTDFFQSRENQEVILEEVRDFQLRDKYMFATKVVHLLGSEQQSSVQLWVSFGRKPMRAAQFVTRHPINEYYIADASEDQVFVCVSHSNNRTNLYISEAEGLKFSLSLENVLYYSPGGAGSDTLVRYFANEPFADFHRVEGLQGVYIATLINGSMNEENMRSVITFDKGGTWEFLQAPAFTGYGEKINCELSQGCSLHLAQRLSQLLNLQLRRMPILSKESAPGLIIATGSVGKNLAS---KTNVYISSSAGARWREALPGPHYYTWGDHGGIITAIAQGMETN-----ELKYSTNEGETWKTFIFS--EKPVFVYGLLTEPGEKS-TVFTIFGSNKENVHSW--------LILQVNATDALG-VPCTENDYKLWSPSDERGNECLLGHKTVFKRRTPHATCFNGEDFDRPVVVSN--CSCTREDYECDFGFKMSEDLSLEVCVPDPEFSGKSYSPPVPCPVGSTYRRTRGYRKISGDTCSGGDVEARLEGELVPCPLAEENEFILYAVRKSIYRYDLASGATEQLPLTGLRAAVALDFDYEHNCLYWSDLALDVIQRLCLNGSTGQEVIINSGLETVEALAFEPLSQLLYWVDAGFKKIEVANPDGDFRLTIVNSSVLDRPRALVLVPQEGVMFWTDWGDLKPGIYRSNMDGSAAYHLVSEDVKWPNGISVDDQWIYWTDAYLECIERITFSGQQRSVILDNLPHPYAIAVFKNEIYWDDWSQLSIFRASKYSGSQMEILANQLTGLMDMKIFYKGKNTGSNACVPRPCSLLCLPKANNSRSCRCPEDVSSSVLPSGDLMCDCPQGYQLKNNTCVKQENTCLRNQYRCSNGNCINSIWWCDFDNDCGDMSDERNCPTTICDLDTQFRCQESGTCIPLSYKCDLEDDCGDNSDESHCEMHQCRSDEYNCSSGMCIRSSWVCDGDNDCRDWSDEANCTAIYHTCEASNFQCRNGHCIPQRWACDGDTDCQDGSDEDPVNCEK-KCNGFRCPNGTCIPSSKHCDGLRDCSDGSDEQHCEPLCTHFMDFVCKNRQQCLFHSMVCDGIIQCRDGSDEDAAFAGCSQDPEFHKVCDEFGFQCQNGVCISLIWKCDGMDDCGDYSDEANCENPTEAPNCSRYFQFRCENGHCIPNRWKCDRENDCGDWSDEKDCGDSHILPFSTPGPSTCLPNYYRCSSGTCVMDTWVCDGYRDCADGSDEEACPLLAN-VTAASTPTQLGRCDRFEFECHQPKTCIPNWKRCDGHQDCQDGRDEANCPTHSTLTCMSREFQCEDGEACIVLSERCDGFLDCSDESDEKACSDELTVYKVQNLQWTADFSGDVTLTWMRPKKMPSASCVYNVYYRVVGESIWKTLETHSNKTNTVLKVLKPDTTYQVKVQVQCLSKAHNTNDFVTLRTPEGLPDAPRNLQLSLPREAEGVIVGHWAPPIHTHGLIREYIVEYSRSGSKMWASQRAASNFTEIKNLLVNTLYTVRVAAVTSRGIGNWSDSKSITTIKGKVIPPPDIHIDSYGENYLSFTLTMESDIKVNGYVVNLFWAFDTHKQERRTLNFRG-SILSHKVGNLTAHTSYEISAWAKTDLGDSPLAFEHVMTRGVRPPAPSLKAKAINQTAVECTWTGPRNVVYGIFYATSFLDLYRNPKSLTTSLHNKTVIVSKDEQYLFLVRVVVPYQGPSSDYVVVKMIPDSRLPPRHLHVVHTGKTSVVIKWESPYDSPDQDLLYAVAVKDLIRKTDRSYKVKSRNSTVEYTLNKLEPGGKYHIIVQLGNMSKDSSIKITTVSLSAPDALKIITENDHVLLFWKSLALKEKHFNESRGYEIHMFDSAMNITAYLGNTTDNFFKISNLKMGHNYTFTVQARCLFGNQICGEPAILLYDELG--SGADASATQAARSTDVAAVVVPILFLILLSLGVGFAILYTKHRRLQSSFTAFANSHYSSRLGSAIFSSGDDLGEDDEDAPMITGFSDDVPMVIA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "X1WHE3-1", "uniprot_id": "X1WHE3_DANRE", "id": "X1WHE3-1", "name": "Sortilin-related receptor", "aln": "MASGQTRKMLALSRCAIYLLLLLVPAAISS--TLRLHHDQRFVLPQDRGFSLVSAHLEPAESRVVRLEREVREASAAHQ-LRVRRNAAGAPVPN-VYGMANLNDSHNQMVVHWAGEKSDVIVALARDSVGATDPKTSSVYVSYDYGANFTPVSEKFQLPREQEDKKQVISQFYHSPADNKR-YLFTDTTNSYLWNTFDFCKTVQGFSIPFKPTDLLLHSKRPNLVLGYDSSHPNKQLWKSDDFGETWVLIQEHVKFYFWGVEPYDNPTTVFVQRHEPQGDSSILTSTDFFQSEQNRRIILEKVDSFQLRDKYMFATTTRALLGSHESQSVQLWVSYNRQPMRAAQFNTRHPITEYYIADASEDQVFVCVNHNNNVTHLYISDTQGLSFSLSLENVLYFSPDGSGSNTLIRYFANEPFADLHRVEGLRGVFVATLINGSVSEDNMRSVITFDKGGTWELLQPPAADSLGGTIDCQLNSGCSLHLAQRWSQLLNIQLRRIPILSKESAPGLIMATGSVGKNMAN---KPNVYVSSSAGVRWREALAGPHFYTWGDHGGILMAIAQGGSSK-----TLKYSTNEGETWKEFQFS--KQEVYVYQLLTEPGEKS-TIFTIFGSYADQKHSW--------LIVQVNASDVLG-VPCSEGDYKLWSPSDERGNGCLLGREMVYKRRSPHATCFNGEDFDRPISLSN--CSCTRQDYECDYGFKLSEDLSLEVCVPDPEFSGNLYAPPVPCPVGTTYHRSKGYRKVSGDSCTGGDVEARLDGENLPCPVGESNEFILYAVRNSIHRYDLASGTDQQLPLTGLHEAVALDFDYEKNCLYWADISLDTIQRLCMNGSSGQEVIVKRDLQNVEALSFDPISRLLYWVDAGAQKIEVSNSDGDLRRTLVNSSVVDQPRALALMPAESLMFWTDWGDRAAGVYRSWMDGSNISCIVSEGVRWPNGITADESWLYWTEAYGDRIERADFNGGSRTVIMEGLPHPYAIAVFKNDLYWDDWSRMGIFKAPKSGSPDSELIVGRLTGVMDLKIFYKGKNRGQNACADQPCSLLCLPQPGNQRHCVCPDGVPTSVLPSGERQCQCPSGYQLHNNTCVKTEHTCLPNQHRCANGKCISSIWKCDSDNDCGDMSDEQECPTTSCDPSVQFRCVASGSCIPLAFKCDHEDDCGDNSDEEHCESHKCGPGEFTCARGACIRDAWRCDGDNDCRDWSDEANCTVGHHTCESSSFQCHTGHCIPQRWVCDGDDDCQDGSDEDPTQCGRQKCNGFLCSNGTCLPASAHCNGVEDCPGGADEQNCGPLCAHYMEFVCRNRAQCLFQSLVCDGTRHCADGSDEDPIYAGCSTSVEFEKTCDGYNFQCTNGMCVTLEWKCDGMDDCGDYSDEANCASPTEEPGCTSYFRFECKNGRCVPAWWKCDGENDCGDWSDESQCSGGEALHTPAPGPATCAPNRFRCGSGACIVDTWVCDGYADCPDSSDEAGCPTVKGSVTSVTTLPPSGRCTKDQFLCVKPPACISDWKRCDGHSHCLDGSDEANCPTHGPLLCAN-GTRCADGEACLLNSERCDGFIDCSDRSDEHNCTDEQQVYKVQNLQWTANFSGAVKLTWTRPKNMPTSSCSFVIYFRPVGVQQWTSIDTNSNKGSAVLTVLMPDTTYNVKVQTQCLSKQHRTNEYLTLRTPEGLPDPPQSLQLSCDKADDGTVLCSWSPPDKTHGHIREYIVEYSEKDSAEWFSLSSTSTNAEVKNLQPSSLYRFRVAAVTSRGVGNWTEIKSIIPQK--ALSPPKVTITSITEDSMSLSISNDYKVKVKLYIVVISWVFDEHVKES----WNYTVPETLKVSNLTAGTEYEVAVWAHTDDGDSPTALSRQQTKGSRPVQPSLKARALNQTAVDCNWTGPPAEMYAVFYATSFLDLFRRPHRVNSTSSSLTVIVDSDEQYLFLVRVVSPYMGPPSNYAVVKMIPDERLPPRNLHKVRVDKTQATLKWQPPYDSPSSPLTYAVHVRDTVRKTESDYKVITQNNTVEYTLKGLEPAGRYSITIRLLNMSKEASYTLSTVPLPAPEALKILEEEDHVFLFWKSLAVKDRTFNESRGYEVYVHDSVTNSTKCLGNTTETFFRINSLLAGHNYTFSVRARCLLSNQLCGESAVLLYDELGKAAGQNDAASQSGKSEDMAAIVVPVLFLLLVGVCGGLVVLYLRHRRLQHSFTAFANSHYNSRLGSAIFSSGDELGDDDEDAPMISGFSDDVPMVIA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P40890-1", "uniprot_id": "VTH2_YEAST", "id": "P40890-1", "name": "VPS10 homolog 2", "aln": "----MALFRALYIIWVFLLIPLSNAEEFTPKVTRTLSRYVFDIVNFDDSNTLIRA--------------EEDSVEISFDAGENWKTIDEIEEPIESFVVDPFRGHDRAFAFVKTAPKFYVTDDQGKSWRPLTIPIS-EKASNYFCDVTTHPIKKKHLIIRC---DLLTIKNSGLMYVG---------------REIYTTNDG-VSFSQVKPSFGKIDG-HISTARCDFIKSSEDSDLGGND---ASILCLFRNTEYIESTG-STIDKSELILSADGGETFKELVQFKDKVVSR--YEILKHHVIVLTQDDMYNEMSSTNIWISNDVST---FQVARTPTKIRHVNMGQIHEDSIGRIVLPVSRERDDEDSNQPGAAEVLISDSEGLKFLP--INWIPNNQFGYINVAYPGFLKGTFFGSFHPFIEYS----DRKRKYSRQKVREETKVSVDNGLTWTNLKVVDRE-NVDLFGCDVTKPERCSLQTHFYDLRNLNP----------SAGIMMISGIVGDGSAYNWKEEKTFISRDSGLTWRLVHNSTGLYTTGDLGNIIMYIPYRSNENGDVPSKFYYSLDQGKTWGEYDL---IMPIYPYRLVSTISDGSGSKFILTGTSITEDPIF--------ITYSIDFSAVFDYKSCEEGDFEDWNLADG---KCVNGAKYKYRRRKQDAQCLVKKAFKDLSLDETPCNSCTGSDYECSFEFVRDAKG---DCIPDYNLIALSDICDK---SKGKSVLVKPLQLIKGDKCKTP---MKIESVDIPCDEIPKEGSSDKEIVTTENKFDFEIKFYQYFDTVADESLVMLNSIGD---AYISHDGGQTIKRFDTDGEKIVEIVFNP-YFNSSAYLFGSKGNIFLTHDRGYSFMIAKLP---------EARQLGMPLDFSAKAQDTFIYYG---------------GKNCESILSPECHAVAYLTKD-------------------GGETFTEMLDNAIH----CEFAGTLFKYPSNDDMVMCQVKEKFSQTRSLVSSTD-------FFQDDRK------------------------TVFENIIGYLSTGGYIIVAVPHEDNELRAYVTNDGAEFTEAKFPYDEDIGKQDAFTILGSEEGSIFLHLATNLESGHDFGNLLKSNSNGTSFVTLEHAVNRNTFG-----------YVDFEKVQGLEGIIITN--IVSNSEKVGENKEDEQLKTKITFNDGSDWNFLK----PPKKDSEGKK--------------------FPCDSVSLDKCSLHLHGYTERKDIRDTYSSGSALG--MMFGVGNVGDRLLPYEECSTFLTTDGGE----------TWTEVKKGPHQWEYGDHGGVLVLVPENAE--TDSISYSTDFG------------------------------------KTWKDYKFCGDKVLVKDIITVPRDSALRFLLFGEAKNMGSGSFRTYTIDFRNIFERQCEFDITGRKRADFKYSPLG-----------------------SRTGCLFG--------HKTEFLRKTDEKCFIG--NIPLSEFSRNVKNCPCTRQDFECDYN--------------------------------------------------FYKASDGTCKLVKGLSSANGADICKKEPDLIEYYDSSGYR---------------KIPLSTCKGGLKLDAHLAPHPCPGKEKAFREKYSINTG-----AYALVFVTILLVIFFVAWFVYDRGIRRNGGFSRFEEIR----------------------------LGDDGLIENN---------------------------RTDRVVNIIVRLGLCISLITKSAFQRAKAGTAQLSSK-FRARFGNKKGATYSSLLHDQLSDEPD----GFHEDSNDLSSFRGQGSNSEIEQEDVDTSQQE-------------HTSRTDLLGASNIPD-ALPARS--ASHESDLAAARSEDK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P40438-1", "uniprot_id": "VTH1_YEAST", "id": "P40438-1", "name": "VPS10 homolog 1", "aln": "----MALFRALYIIWVFLLIPLSNAEEFTPKVTRTLSRYVFDIVNFDDSNTLIRA--------------EEDSVEISFDAGENWKTIDEIEEPIESFVVDPFRGHDRAFAFVKTAPKFYVTDDQGKSWRPLTIPIS-EKASNYFCDVTTHPIKKKHLIIRC---DLLTIKNSGLMYVG---------------REIYTTNDG-VSFSQVKPSFGKIDG-HISTARCDFIKSSEDSDLGGND---ASILCLFRNTEYIESTG-STIDKSELILSADGGETFKELVQFKDKVVSR--YEILKHHVIVLTQDDMYNEMSSTNIWISNDVST---FQVARTPTKIRHVNMGQIHEDSIGRIVLPVSRERDDEDSNQPGAAEVLISDSEGLKFLP--INWIPNNQFGYINVAYPGFLKGTFFGSFHPFIEYS----DRKRKYSRQKVREETKVSVDNGLTWTNLKVVDRE-NVDLFGCDVTKPERCSLQTHFYDLRNLNP----------SAGIMMISGIVGDGSAYNWKEEKTFISRDSGLTWRLVHNSTGLYTTGDLGNIIMYIPYRSNENGDVPSKFYYSLDQGKTWGEYDL---IMPIYPYRLVSTISDGSGSKFILTGTSITEDPIF--------ITYSIDFSAVFDYKSCEEGDFEDWNLADG---KCVNGAKYKYRRRKQDAQCLVKKAFKDLSLDETPCNSCTGSDYECSFEFVRDAKG---DCIPDYNLIALSDICDK---SKGKSVLVKPLQLIKGDKCKTP---MKIESVDIPCDEIPKEGSSDKEIVTTENKFDFEIKFYQYFDTVADESLVMLNSIGD---AYISHDGGQTIKRFDTDGEKIVEIVFNP-YFNSSAYLFGSKGNIFLTHDRGYSFMIAKLP---------EARQLGMPLDFSAKAQDTFIYYG---------------GKNCESILSPECHAVAYLTKD-------------------GGETFTEMLDNAIH----CEFAGTLFKYPSNDDMVMCQVKEKFSQTRSLVSSTD-------FFQDDRK------------------------TVFENIIGYLSTGGYIIVAVPHEDNELRAYVTNDGAEFTEAKFPYDEDIGKQDAFTILGSEEGSIFLHLATNLESGHDFGNLLKSNSNGTSFVTLEHAVNRNTFG-----------YVDFEKVQGLEGIIITN--IVSNSEKVGENKEDEQLKTKITFNDGSDWNFLK----PPKKDSEGKK--------------------FPCDSVSLDKCSLHLHGYTERKDIRDTYSSGSALG--MMFGVGNVGDRLLPYEECSTFLTTDGGE----------TWTEVKKGPHQWEYGDHGGVLVLVPENAE--TDSISYSTDFG------------------------------------KTWKDYKFCGDKVLVKDIITVPRDSALRFLLFGEAKNMGSGSFRTYTIDFRNIFERQCEFDITGRKRADFKYSPLG-----------------------SRTGCLFG--------HKTEFLRKTDEKCFIG--NIPLSEFSRNVKNCPCTRQDFECDYN--------------------------------------------------FYKASDGTCKLVKGLSSANGADICKKEPDLIEYYDSSGYR---------------KIPLSTCKGGLKLDAHLAPHPCPGKEKAFREKYSINTG-----AYALVFVTILLVIFFVAWFVYDRGIRRNGGFSRFEEIR----------------------------LGDDGLIENN---------------------------RTDRVVNIIVRLGLCISLITKSAFQRAKAGTAQLSSK-FRARFGNKKGATYSSLLHDQLSDEPD----GFHEDSNDLSSFRGQGSNSEIEQEDVDTSQQE-------------HTLRTDLLGASNIPD-ALPARS--ASHESDLAAARSEDK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P53751-1", "uniprot_id": "YN94_YEAST", "id": "P53751-1", "name": "Uncharacterized membrane glycoprotein YNR065C", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLMTGSVGDGSEFDWEDQKTFISRDGGLTWRFVHNSSGLYATGDLGNIIVYIPYDPEEDGDFQSEFYYSLDQGRTWNEYELTNAISSVHPYKLINPTPDGSGSKFIFKGTFATTDSETNSITSLKGVEYIIDFSAAFDSRTCEEEDFEDWDLADG---KCVNGAKYKYRRRKQDAQCLVKKAFKDLSLDETPCNSCGESDYECSFEFVRDANG---LCIPDYNLIAFSNICDK---SKDKSVLVEPLQLIKGDECKTP---MKIEPVDIPCDEIPEEGSSDREIVTTENKFDFEIKFYQYFDTVADESLVMLNSIGD---AYISHDGGQTIKRFDTNGEKIVEVVFNP-YFNSSAYLFGSKGNIFSTHDRGHSFMIAKLP---------EARQLGMPLDFSAKAQDTFIYYG---------------GKNCESILSPECHAVAYLTKD-------------------GGETFTEMLDNAIH----CEFAGTLFEYPSNEEMVMCQVKKKSSETRSLVSSID-------FFQGDNK------------------------IIFENIIGYLSTGGYIIVAVPHEDNELRAYVTIDGTEFAEAKFPYGQDVSKQEAFTILGSEKGSIFLHLATNLESGHDFGNLLKSNSNGTSFVTLEHAVNRNTFG-----------YVDFEKVQGLEGIIITN--IVSNREKVGENKEDEQLKTKITFNDGSDWNFLK----PPKKDSEGKK--------------------FPCDSVSLDKCSLHLHGYTERKDIRDTYSSGSALG--MMFGVGNVGDKLLPYEECSTFLTTDGGE----------TWTEVKKGPHQWEYGDHGGVLVLVPENAE--TDSISYSTDFG------------------------------------KTWKDYKFCGDKVLVKDIITVPRDSALRFLLFGEAKNMGSGSFRTYTIDFRNIFERQCEFDITGKKRADFKYSPLG-----------------------SRTGCLFG--------HQTEFLRKTDEKCFIG--NIPLSEFSRNVKNCSCTRQDFECDYN--------------------------------------------------FYKASDGTCKLVKGLSSANGADICKKEPDLIEYYDSSGYR---------------KIPLSTCKGGLKLDAHLAPHPCPGKEKAFREKYSINTG-----AYALVFVTILLVIFFAAWFVYDRGIRRNGGFSRFEEIR----------------------------LGDDGLIENN---------------------------RTDRVVNIIVRLGLCISLITKSAFQRTKAGVARFSSK-LRARFGNRKGPTYSSLLQGQFSDESD----GLHEDANDLSSFTSQDSNFEIEQEDAYRPEQE-------------HTSQIDQPATSNIPD-ALPARS--AIHKPDSTAVRNEDE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P32319-1", "uniprot_id": "VPS10_YEAST", "id": "P32319-1", "name": "Vacuolar protein sorting/targeting protein VPS10", "aln": "----MILLHFVYSLWALLLIPLTNAEEFTPKVTKTIAQDSFDILSFDDSNTLIRK--------------QDTSVTISFDDGETWEKVEGIEGEITWIYIDPFNRHDRAVATAMNGSYLYITNDQGKSWERITLPDSGESISPRECYIETHPLNKNYFLAKCNYCEKTEVNNDNEENSGDEEGQFEIFNITRCTDKVFASNDGGKSFSEIKSSLERNENSPISISDCGFAKTSKDSDLESSD---TSIICLFQNMQLIMDEFSSPYTESKLVLTTDWGKSLKEFDQFKDKVVNG--YRILKSHMVVLTQGDRYNDMSSMDVWVSNDLSN---FKMAYMPTQLRHSMQGEIYEDAMGRIILPMSRERSDQEEDKGIVSEILISDSQGLKFSP--IPWTANEVFGYINFYQPTYLKGTMIASLYPLSRRR----NRKGKAKGVKSKGVTKISVDNGLTWTMLKVVDPD-NADSFDCDITDFENCSLQNMFYTREGSTP----------TAGILMTTGIVGDGSVFDWGDQRTFISRDGGLTWKLAFDFPCLYAVGDYGNVIVAIPYNADEDDDPQSEFYYSLDQGKTWTEYQL---ETTIYPNEVMNTTPDGSGAKFILNGFTLAHMDGTTN------FIYAIDFSTAFNDKTCEENDFEDWNLAEG---KCVNGVKYKIRRRKQDAQCLVKKVFEDLQLFETACDKCTEADYECAFEFVRDATG---KCVPDYNLIVLSDVCDK---TKKKTVPVKPLQLVKGDKCKKP---MTVKSVDISCEGVPKKGTNDKEIVVTENKFDFKIQFYQYFDTVTDESLLMINSRGE---AYISHDGGQTIKRFDSNGETIIEVVFNP-YYNSSAYLFGSKGSIFSTHDRGYSFMTAKLP---------EARQLGMPLDFNAKAQDTFIYYG---------------GKNCESILSPECHAVAYLTND-------------------GGETFTEMLDNAIH----CEFAGSLFKYPSNEDMVMCQVKEKSSQTRSLVSSTD-------FFQDDKN------------------------TVFENIIGYLSTGGYIIVAVPHENNELRAYVTIDGTEFAEAKFPYDEDVGKQEAFTILESEKGSIFLHLATNLVPGRDFGNLLKSNSNGTSFVTLEHAVNRNTFG-----------YVDFEKIQGLEGIILTN--IVSNSDKVAENKEDKQLKTKITFNEGSDWNFLK----PPKRDSEGKK--------------------FSCSSKSLDECSLHLHGYTERKDIRDTYSSGSALG--MMFGVGNVGPNLLPYKECSTFFTTDGGE----------TWAEVKKTPHQWEYGDHGGILVLVPENSE--TDSISYSTDFG------------------------------------KTWKDYKFCADKVLVKDITTVPRDSALRFLLFGEAADIGGSSFRTYTIDFRNIFERQCDFDITGKESADYKYSPLG-----------------------SKSNCLFG--------HQTEFLRKTDENCFIG--NIPLSEFSRNIKNCSCTRQDFECDYN--------------------------------------------------FYKANDGTCKLVKGLSPANAADVCKKEPDLIEYFESSGYR---------------KIPLSTCEGGLKLDAPSSPHACPGKEKEFKEKYSVSAG-----PFAFIFISILLIIFFAAWFVYDRGIRRNGGFARFGEIR----------------------------LGDDGLIENN---------------------------NTDRVVNNIVKSGFYVFSNIGSLLQHTKTNIAHAISK-IRGRFGNRTGPSYSSLIHDQFLDEADDLLAGHDEDANDLSSFMDQGSNFEIEEDDVPTLEEE-------------HTSYTDQPTTTDVPD-TLPEGNEENIDRPDSTAPSNENQ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: :* **.. . ..::* ..* *: . . *: ** *.:: *. . . : ** ::*.** : : :. ::. : * : * : * . :: : .:. .* * *:: *. :: *: * : :**. .* *: : *. .. .* **** : * . *:** :: . . : :.** *. :. :.* .: : : ::*: : : . : :: : * :. . :.*:*: :*.. *::.: . .* * . . :: * * . : . . :: :. * : . : .::: *. ::* : :: * .* : :::. * . * . :: . :: * .: . :.. *::... :.: : ..* * : . . :. :. .. : .:. . : . . * . ::. .*:.: :. .: * : * : . .. :. : .:: : .. :.*.:: . * : .:*. * * . : .* * .* : . * . . * * * *: *. .*. *..* . : : .*: : : :.: *. .** : . *.* . *.. . . * . . ... : . . * : :. : . : . . * .: * * * . . .* * : ** . .. :*. :: * : : . .: ::. * . . :: : * : . :. : ::. * : .* * : : :** . . : : : : : : . . *...: : : : : :: : : :* * . : : : : :: . .. : .. . . :. *. : . . ..: : .. :** ** . . . : ", "identical_positions": 119, "similar_positions": 357, "identity": "5.3%" }, { "cls_id": "homologset.agr.MGI:1202298", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZLL5-1", "uniprot_id": "A0A8I5ZLL5_RAT", "id": "A0A8I5ZLL5-1", "name": "Glycylpeptide N-tetradecanoyltransferase", "aln": "MAEDSESAASQQSLELDDQDTCGIDGDNEEETEHAKGSPGGDLGAKKKKKKQKRKKEKPNSGGTKSDSASDSQEIKIQQSSKHNAIWQQISAGAAMGGDTMEGEWIDLRMYHKNPTIPIQKLQDIQRAMELLSACQGPARNIDEATKRRYQFWDTQPVPKLNEVITSHGAIEPDK--DNIRQEPYSLPQGFMWDTLDLSNAEVLKELYTLLNENYVEDDDNMFRFDYSPEFLLWALRPPGWLLQWHCGVRVSSNKKLVGFISAIPANIRIYDSVKRMVEINFLCVHKKLRSKRVAPVLIREITRRVNLEGIFQAVYTAGVVLPKPVATCRYWHRSLNPRKLVEVKFSHLSRNMTLQRTMKLYRLPDVTKTSGLRPMEPKDIRAVRELINVYLKQFHLAPVMGDEEVAHWFLPRE------HIIDTFVVESPSGKLTDFLSFYTLPSTVMHHPAHKSLKAAYSFYNIHT-----------------ETPLLDLMNDALIIAKLKGFDVFNALDLMENKTFLEKLKFGIGDGNLQYYLYNWRCP----GTDSEK---------VGLVLQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70311-1", "uniprot_id": "NMT2_MOUSE", "id": "O70311-1", "name": "Glycylpeptide N-tetradecanoyltransferase 2", "aln": "MAEDSESAASQQSLELDDQDTCGIDGDNEEETEHAKGSPGGDLGAKKKKKKQKRKKEKPNSGGTKSDSASDSQEIKIQQSSKHNAIWQQISAGAAMGGDTMEGEWIDLRMYHKNPTIPIQKLQDIQRAMELLSACQGPARNIDEATKRRYQFWDTQPVPKLNEVITSHGAIEPDK--DNIRQEPYSLPQGFMWDTLDLSNAEVLKELYTLLNENYVEDDDNMFRFDYSPEFLLWALRPPGWLLQWHCGVRVSSNKKLVGFISAIPANIRIYDSVKRMVEINFLCVHKKLRSKRVAPVLIREITRRVNLEGIFQAVYTAGVVLPKPVATCRYWHRSLNPRKLVEVKFSHLSRNMTLQRTMKLYRLPDVTKTSGLRPMEPKDIKAVRELINIYLKQFHLAPVMDDAEVAHWFLPRE------HIIDTFVVENPSGKLTDFLSFYTLPSTVMHHPAHKSLKAAYSFYNIHT-----------------ETPLLDLMNDALIIAKLKGFDVFNALDLMENKTFLEKLKFGIGDGNLQYYLYNWRCP----GTDSEK---------VGLVLQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60551-1", "uniprot_id": "NMT2_HUMAN", "id": "O60551-1", "name": "Glycylpeptide N-tetradecanoyltransferase 2", "aln": "MAEDSESAASQQSLELDDQDTCGIDGDNEEETEHAKGSPGGYLGAKKKKKKQKRKKEKPNSGGTKSDSASDSQEIKIQQPS-------------------------------KNPSVPMQKLQDIQRAMELLSACQGPARNIDEAAKHRYQFWDTQPVPKLDEVITSHGAIEPDK--DNVRQEPYSLPQGFMWDTLDLSDAEVLKELYTLLNENYVEDDDNMFRFDYSPEFLLWALRPPGWLLQWHCGVRVSSNKKLVGFISAIPANIRIYDSVKKMVEINFLCVHKKLRSKRVAPVLIREITRRVNLEGIFQAVYTAGVVLPKPIATCRYWHRSLNPRKLVEVKFSHLSRNMTLQRTMKLYRLPDVTKTSGLRPMEPKDIKSVRELINTYLKQFHLAPVMDEEEVAHWFLPRE------HIIDTFVVESPNGKLTDFLSFYTLPSTVMHHPAHKSLKAAYSFYNIHT-----------------ETPLLDLMSDALILAKSKGFDVFNALDLMENKTFLEKLKFGIGDGNLQYYLYNWRCP----GTDSEK---------VGLVLQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A7YT82-1", "uniprot_id": "NMT2_DANRE", "id": "A7YT82-1", "name": "Glycylpeptide N-tetradecanoyltransferase 2", "aln": "MAEDSESAASQQSLELDDQDTCGIDGDNEEENEHMQGSPGGDLGAKKKKKKQKRKKEKPSSGGTKSDSASDSQEIK-------------------------------------NPAIPMQKLQDIQRAMELLSTCQGPAKNIDEATKHKYQFWDTQPVPKLNEVVTTHGPIEPDK--ENIRQEPYSLPQGFMWDTLDLSNAEVLKELYTLLNENYVEDDDNMFRFDYSPNFLKWALRPPGWLPHWHCGVRVSSNKKLVGFISAIPADIHIYDTLKRMVEINFLCVHKKLRSKRVAPVLIREITRRVNLEGIFQAVYTAGVVLPKPVSTCRYWHRSLNPRKLVEVKFSHLSRNMTLQRTMKLYRLPDSTRTPGLRTMGDRDVKQVTALLQKHLSQFHLRPVMGEEEVKHWFLPQE------NIIDTFVVEGSGGMLTDFISFYTLPSTVMHHPLHKSLKAAYSFYNVHT-----------------ETPLIDLMNDALILAKLKGFDVFNALDLMDNKNFLEKLKFGIGDGNLQYYLYNWKCP----PMDPEK---------VGLVLQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O61613-1", "uniprot_id": "NMT_DROME", "id": "O61613-1", "name": "Glycylpeptide N-tetradecanoyltransferase", "aln": "MPNENAEDLSGQELKQKAKEVA-----DASEAMLEKVVAGLNIQDTASTNAAGNEDAEQPDGAKNEASVSAN--------------------------------------------------ASKQALLQAVSDAMASTR----QMAKKFAFWSTQPVTKLDEQVTTNECIEPNKEISEIRALPYTLPGGFKWVTLDLNDANDLKELYTLLNENYVEDDDAMFRFDYQPEFLKWSLQPPGWKRDWHVGVRVEKSGKLVGFISAIPSKLKSYDKVLKVVDINFLCVHKKLRSKRVAPVLIREITRRVNLTGIFQAAYTAGVVLPTPVATCRYWHRSLNPKKLVDVRFSHLARNMTMQRTMKLYKLPDQPKTKGYRRITAKDMDKAHKLLEDYLKRFQLSPVFSKEEFRHWFTPKE------GIIDCFVVADEKGNITDLTSYYCLPSSVMHHPVHKTVRAAYSFYNVST-----------------KTPWLDLMNDALISARNVQMDVYNALDLMENKKYFAPLKFGAGDGNLQYYLYNWRCP----SMQPEE---------IALILM", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P14743-1", "uniprot_id": "NMT_YEAST", "id": "P14743-1", "name": "Glycylpeptide N-tetradecanoyltransferase", "aln": "MSEEDKAKKLENLLKL------------------------LQLNNDDTSKFTQEQKK----------------------------------------------------------------------------------------AMKDHKFWRTQPVKDFDEKVVEEGPIDKPKTPEDISDKPLPLLSSFEWCSIDVDNKKQLEDVFVLLNENYVEDRDAGFRFNYTKEFFNWALKSPGWKKDWHIGVRVKETQKLVAFISAIPVTLGVRGKQVPSVEINFLCVHKQLRSKRLTPVLIKEITRRVNKCDIWHALYTAGIVLPAPVSTCRYTHRPLNWKKLYEVDFTGLPDGHTEEDMIAENALPAKTKTAGLRKLKKEDIDQVFELFKRYQSRFELIQIFTKEEFEHNFIGEESLPLDKQVIFSYVVEQPDGKITDFFSFYSLPFTILNNTKYKDLGIGYLYYYATDADFQFKDRFDPKATKALKTRLCELIYDACILAKNANMDVFNALTSQDNTLFLDDLKFGPGDGFLNFYLFNYRAKPITGGLNPDNSNDIKRRSNVGVVML", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.::. : *: : ..: .:. : . ** **** .::* :. . *: * .:: * .* .* * ::*:.: : *::::.********* * ***:* :*: *:*:.*** .** ****... ***.****** : .. *:********:*****::****:******* .*::* ****:*** *::**** **.** :** :* *: *. . * : : ** .:* * * : .*: . *:: : .:*.* :: . *. * * .* :* :** * :**: *:* ** :::::. :* : .* :* :* :*: ** * *: :**:*** :*. :: **** *** *::**:*::. :.:: :.::: ", "identical_positions": 150, "similar_positions": 128, "identity": "26.46%" }, { "cls_id": "homologset.agr.MGI:1202299", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O54897-1", "uniprot_id": "GPR27_MOUSE", "id": "O54897-1", "name": "Probable G protein-coupled receptor 27", "aln": "MANASEPGGGGSGGGAEAAALGLRLATLSLLLCVSLAGNVLFALLIVRERSLHRAPYYLLLDLCLADGLRALACLPAVMLAARRAAAAAGTPPGALGCKLLAFLAALFCFHAAFLLLGVGVTRYLAIAHHRFYAERLAGWPCAAMLVCAAWALALAAAFPPVLDGGGADDEDAPCALEQRPDGAPGALGFLLLLAAVVGATHLVYLRLLFFIHDRRKMRPARLVPAVSHDWTFHGPGATGQAAANWTAGFGRGPTPPALVGIRPAGPGRGARRLLVLEEFKTEKRLCKMFYAITLLFLLLWGPYVVASYLRVLVRPGAVPQAYLTASVWLTFAQAGINPVVCFLFNRELRDCFRAQFPCCQSPQATQATLPCDLKGIGL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9JJH3-1", "uniprot_id": "GPR27_RAT", "id": "Q9JJH3-1", "name": "Probable G protein-coupled receptor 27", "aln": "MANASEPGGGG--GGAEAAALGLRLATLSLLLCVSLAGNVLFALLIVRERSLHRAPYYLLLDLCLADGLRALACLPAVMLAARRAAAAAGTPPGALGCKLLAFLAALFCFHAAFLLLGVGVTRYLAIAHHRFYAERLAGWPCAAMLVCAAWALALAAAFPPVLDGGGADDEDAPCALEQRPDGAPGALGFLLLLAAVVGATHLVYLRLLFFIHDRRKMRPARLVPAVSHDWTFHGPGATGQAAANWTAGFGRGPTPPALVGIRPAGPGRGARRLLVLEEFKTEKRLCKMFYAITLLFLLLWGPYVVASYLRVLVRPGAVPQAYLTASVWLTFAQAGINPVVCFLFNRELRDCFRAQFPCCQSPQATQATLPCDLKGIGL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NS67-1", "uniprot_id": "GPR27_HUMAN", "id": "Q9NS67-1", "name": "Probable G protein-coupled receptor 27", "aln": "MANASEPGGSG---GGEAAALGLKLATLSLLLCVSLAGNVLFALLIVRERSLHRAPYYLLLDLCLADGLRALACLPAVMLAARRAAAAAGAPPGALGCKLLAFLAALFCFHAAFLLLGVGVTRYLAIAHHRFYAERLAGWPCAAMLVCAAWALALAAAFPPVLDGGG-DDEDAPCALEQRPDGAPGALGFLLLLAVVVGATHLVYLRLLFFIHDRRKMRPARLVPAVSHDWTFHGPGATGQAAANWTAGFGRGPTPPALVGIRPAGPGRGARRLLVLEEFKTEKRLCKMFYAVTLLFLLLWGPYVVASYLRVLVRPGAVPQAYLTASVWLTFAQAGINPVVCFLFNRELRDCFRAQFPCCQSPRTTQATHPCDLKGIGL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*********.* *.*******:******************************************************************:**************************************************************************** ***************************.************************************************************************************************:**********************************************************************::**** *********", "identical_positions": 366, "similar_positions": 8, "identity": "96.57%" }, { "cls_id": "homologset.agr.MGI:1202300", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A6Z8-1", "uniprot_id": "KCNU1_RAT", "id": "D4A6Z8-1", "name": "Potassium channel subfamily U member 1", "aln": "MSQTLLDN---------------LNKKELTETSCTIEIQA----------AFILSSLATFFGGLIVLFIFRIALKISRNWKTVKGPRGILELFSSRRIEVNPLRKLYFHGVFRERIEMLLSAQTIVGQVLVILVFVLSIGSLVIYFIN-SMDPVRKCSSYEDKIVH-VDLSFNAFFSFYFGLRFWAAEDKIKFWLEMNSIVDIFTIPPTFISYYLKSNWLGLRFLRALRLLELPKILQILQVIKTSNSVKLSKLMSIVISTWFTAAGFLHLVENSGDPWLNGRNSQTMSYFESIYLVTATMSTVGFGDVVAKTSLGRIFIVFFTLGSLILFANYIPEMVELFSTRKKYNKPYEAVKGKKFIVVCGNITIDSVTAFLRNFLHRKAGEINIEIVFLGEAPPSVELETLLKCHTSCTTFVCGTALKFEDLKRVAVENAEACLILANPFCSDLHDEDNSNIMRVLSIKNYYPQTRVIIQMLQSQNKVFLSRIPNWNWSAGDNIICFAELKLGFIAQGCLVPGLCTFLTTLFIEQNQKVFP-KHPWQKHFLNGLKNKILTQRLSNDFVGMTFPQVSRLCFLKMHLMLIAIQHKPLFHN-CCSLILNPSSQVRLNKDTLGFFIAESSKDVKRALFYCSNCHSDVCNPELIGKCGCKNRSRQ---------------------------------------------------------------------QLVAPTIMVMQSSLNEFAP--------TAEIYTSISREQTSSVTILTTR-------NMPVDTADDSDM----------LDSSGMFHWCRSMPLDKVVLKRSDKATHEFQNHIVACVFGDAHSSLMGLRNFVMPLRASNYTRQELKDIVFIGSLEYFQREWRFLRNFPKIHIMPGSALYTGDLHAVNVEQCSMCVILATPYKALSSQLLVDTETIMATLNIQALRISCPMSGSSK--------KEVNTSPTFSKYEGKQRYQQIPILTELKNPSNIHFIEQMDGLDEAIKGTSLHLSTAFSTGTVFSGTFLDSLLATAFYNYHVLELLQMLVTGGINSQTEHCLVKEKLYEGNEGGATFLSGRTRCKLGLLSLDETILSDIKPKKTFGQLFCGSLDNLGILCVGLYRMMDEGE-HNSERKRFVITRPANECHLLPSDLVFCAIPFSITCDKSESNASIQDQDTTTN---VTS-MSQGSNFQGAQSALNEHSLSPASAMGEKKSPQLLNSRVYPLNLFDASDIDPGK------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O54982-1", "uniprot_id": "KCNU1_MOUSE", "id": "O54982-1", "name": "Potassium channel subfamily U member 1", "aln": "MSQTLLDS---------------LNQKELTETSCTIEIQA----------AFILSSLATFFGGLIILFLFRIALKSSRSWKYVKGPRGLLELFSSRRIEANPLRKLYFHGVFRQRIEMLLSAQTVVGQVLVILVFVLSIGSLVIYFIN-SMDPVRRCSSYEDKIVH-VDLSFNAFFSFYFGLRFWAAEDKIKFWLEMNSIVDIFTIPPTFISYYLKSNWLGLRFLRALRLLELPKILQILQVIKTSNSVKLSKLLSIVISTWFTAAGFLHLVENSGDPWLNGRNSQTMSYFESIYLVTATMSTVGFGDVVAKTSLGRIFIVFFTLGSLILFANYIPEMVELFSTRKKYTKPYEAVKGKKFIVVCGNITVDSVTAFLRNFLHWKSGEINIEIVFLGETLPCLELETLLKCHTSCTNFVCGTALKFEDLKRVAVENSEACLILANHFCSDLHDEDNSNIMRVLSIKNYYPQTRVIIQILQSQNKVFLSKIPNWDWSAGDNILCFAELKLGFIAQGCLVPGLCTFLTTLFIEQNQKVFP-KHPWQKHFLNGLKNKILTQRLSNDFVGMTFPQVSRLCFVKLNLMLIAIQHKPFFHS-CCTLILNPSSQVRLNKDTLGFFIADSSKAVKRAFFYCSNCHSDVCNPELIGKCNCKIKSRQ---------------------------------------------------------------------QLIAPTIMVMKSSLTDFTTSSHIHASMSTEIHTCFSREQPSLITITTNR-------PTTNDTVDDTDM----------LDSSGMFHWCRAMPLDKVVLKRSEKAKHEFQNHIVVCVFGDAQCTLVGLRNFVMPLRASNYTRQELKDIVFIGSLEYFQREWRFLRNFPKIHIMPGSALYMGDLIAVNVEQCSMCVILATPYKALSSQILVDTEAIMATLNIQSLRITSPTPGSSK--------SEVKPSSAFDSKERKQRYKQIPILTELKNPSNIHFIEQMGGLDGMLKGTSLHLSTSFSTGAVFSDTFLDSLLATSFYNYHVVELLQMLVTGGISSEMEHYLVKEKPYKTTDDYEAIKSGRTRCKLGLLSLDQTVLSGINPRKTFGQLFCGSLDNFGILCVGLYRMIDEEE-PSQEHKRFVITRPSNECHLLPSDLVFCAIPFNTTCGKSDSSPSIQAQNNSTN---ATTPLAQGSNFFDSHHADESHDLYPVDDTGERWS-QHHHSRVYPLDTLDASDIVQEK------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A8MYU2-1", "uniprot_id": "KCNU1_HUMAN", "id": "A8MYU2-1", "name": "Potassium channel subfamily U member 1", "aln": "MFQTKLRN---------------ETWEDLPKMSCTTEIQA----------AFILSSFVTFFSGLIILLIFRLIWRSVKKWQIIKGTGIILELFTSGTIARSHVRSLHFQGQFRDHIEMLLSAQTFVGQVLVILVFVLSIGSLIIYFIN-SADPVGSCSSYEDKTIP-IDLVFNAFFSFYFGLRFMAADDKIKFWLEMNSIVDIFTIPPTFISYYLKSNWLGLRFLRALRLLELPQILQILRAIKTSNSVKFSKLLSIILSTWFTAAGFIHLVENSGDPWLKGRNSQNISYFESIYLVMATTSTVGFGDVVAKTSLGRTFIMFFTLGSLILFANYIPEMVELFANKRKYTSSYEALKGKKFIVVCGNITVDSVTAFLRNFLRDKSGEINTEIVFLGETPPSLELETIFKCYLAYTTFISGSAMKWEDLRRVAVESAEACLIIANPLCSDSHAEDISNIMRVLSIKNYDSTTRIIIQILQSHNKVYLPKIPSWNWDTGDNIICFAELKLGFIAQGCLVPGLCTFLTSLFVEQNKKVMP-KQTWKKHFLNSMKNKILTQRLSDDFAGMSFPEVARLCFLKMHLLLIAIEYKSLFTDGFCGLILNPPPQVRIRKNTLGFFIAETPKDVRRALFYCSVCHDDVFIPELITNCGCKSRSRQ---------------------------------------------------------------------HITVPSVKRMKKCLKGISSR------ISGQDSPPRVSASTSSISNFTTR-------TLQHDVEQDSDQ----------LDSSGMFHWCKPTSLDKVTLKRTGKSKYKFRNHIVACVFGDAHSAPMGLRNFVMPLRASNYTRKELKDIVFIGSLDYLQREWRFLWNFPQIYILPGCALYSGDLHAANIEQCSMCAVLSPPPQPSSNQTLVDTEAIMATLTIGSLQIDSSSDPSPS--------VSEETPGYTNGHNEKSNCRKVPILTELKNPSNIHFIEQLGGLEGSLQETNLHLSTAFSTGTVFSGSFLDSLLATAFYNYHVLELLQMLVTGGVSSQLEQHLDKDKVYGVADSCTSLLSGRNRCKLGLLSLHETILSDVNPRNTFGQLFCGSLDLFGILCVGLYRIIDEEE-LNPENKRFVITRPANEFKLLPSDLVFCAIPFSTACYKRNEEFSLQKSYEIVNKASQTTETHSDTNCPPTIDSVTETLYSPVYSYQPRTN-SLSFPKQIAWNQSRTNSIISSQIPLGDNAKENERKTSDEVYDEDPFAYSEPL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q03720-1", "uniprot_id": "SLO_DROME", "id": "Q03720-1", "name": "Calcium-activated potassium channel slowpoke", "aln": "MASGLIDTNFSSTLANGMSGCDQSTVESLADDPTDSPFDADDCLKVRKYWCFLLSSIFTFLAGLLVVLLWRAFAFVCCRKEPDLGPNDPKQKEQKASRNKQEFEGTFMT-EAKDWAGELISGQTTTGRILVVLVFILSIASLIIYFVDASSEEVERCQKWSNNITQQIDLAFNIFFMVYFFIRFIAASDKLWFMLEMYSFVDYFTIPPSFVSIYLDRTWIGLRFLRALRLMTVPDILQYLNVLKTSSSIRLAQLVSIFISVWLTAAGIIHLLENSGDP-LDFNNAHRLSYWTCVYFLIVTMSTVGYGDVYCETVLGRTFLVFFLLVGLAMFASSIPEIIELVGSGNKYGGELKREHGKRHIVVCGHITYESVSHFLKDFLHEDREDVDVEVVFLHRKPPDLELEGLFKRHFTTVEFFQGTIMNPIDLQRVKVHEADACLVLANKYCQDPDAEDAANIMRVISIKNYSDDIRVIIQLMQYHNKAYLLNIPSWDWKQGDDVICLAELKLGFIAQSCLAPGFSTMMANLFAMRSFKTSPDMQSWTNDYLRGTGMEMYTETLSPTFIGIPFAQATELCFSKLKLLLLAIEIKGAEEGADSKISINPRG-AKIQANTQGFFIAQSADEVKRAWFYCKACHEDIKDETLIKKCKCKNLTVQPRSKFDDLDEHHPAPTFTPPELPKRVHVRGSVSGDITRDREDTNLLNRNVRRPNGTGNGTGGMHHMNNTAAAAAAAAAAGKQVNKVKPTVNVSRQVEGQVISPSQYNRPTSRSSGTGTQNQNGGVSLPAGIADDQSKDFDFEKTEMKYDSTGMFHWSPAKSLEDCILDRNQAAMTVLNGHVVVCLFADPDSPLIGLRNLVMPLRASNFHYHELKHVVIVGSVDYIRREWKMLQNLPKISVLNGSPLSRADLRAVNVNLCDMCCILSAKVPSNDDPTLADKEAILASLNIKAMTFDDTIGVLSQRGPEFDNLSATAGSPIVLQRRGSVYGANVPMITELVNDSNVQFLDQDDDDD---PDTELYLTQPFACGTAFAVSVLDSLMSTTYFNQNALTLIRSLITGGATPELELILAEGAGLRGGYSTVESLSNRDRCRVGQISLYDGPLAQFGECGKYGDLFVAALKSYGMLCIGLYRFRDTSSSCDASSKRYVITNPPDDFSLLPTDQVFVLMQFDPGLEYKPPAVRAPAGGRGTN--------TQGSGVGGGGSNKDDNS-----------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . : . . :.*.. . ::* .*:***: **:.**::::::* : *. : . . .. .: :: *:*.** .*::**:***:***.**:***:: * : * *..:.:: :** ** ** .** :** **.**: * *** *:** *****:*:* **. .*:**********: :*.*** *..:***.*:::::*:**.:*.*:****::**:****** *. .*:: :**: .:*:: .* ****:*** .:* *** *::** * .* :**. ***::**... .** : :**:.*****:** :**: **::**: . ::: *:*** . * :*** ::* : : . *. *: :: **:** *..::***::** *.* . ** :*****:***** *:***::* :**.:* .**.*:*. **:::*:**********.**.**:.*:::.** :. *. * :.* :.:*.. :: *: ** * *:.*.:.:.*** *::*:*:**: * . . : :** .::. :* *****::.. *:** ***. **.*: ** :* ** : * ..: . :. . . : . .: : * . :* . **:*****. . .*:. *.*. : :..*:*.*:*.*.... :****:********: :***.:*::**::*::***::* *:*:* :: *..* .** *.*:: *.** :*:. . .. *.*.*:*:*:*.* :: : . .. . . . ::*::*** * **::*::* .. : *.*:*: .*: *:.*: :.****::*:::* :.: *:: *:*** ..: * * : . *.* **::* :** : *: . .:*:** .:*. *:**:****: * . . . **:***.*.:: ***:* ** : *. .* ..:. . ", "identical_positions": 378, "similar_positions": 362, "identity": "29.55%" }, { "cls_id": "homologset.agr.MGI:1202301", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8C863-1", "uniprot_id": "ITCH_MOUSE", "id": "Q8C863-1", "name": "E3 ubiquitin-protein ligase Itchy", "aln": "MSD--------------SGPQLDSMGSLTMKS-----------------QLQITVISAKLKENKKNWFGPSPYVEVTVDGQSK-KTEKCNNTNSPKWKQPLTV-IVTPTSKLCFRVWSHQTLKS--DVLLGTAGLDIYETLKSNN--MKLEEVVMTLQLVGDKEPTET-MGDLSVCLDGLQVEAEVVTNGETSCSES-----------------------------------------TTQNDDGCRTRDDTRVSTNGSEDPEV-----AASGENKR---------------ANGNNSPSLSNG--GFKPSRPPRPSRPPPPTPRRPAS-VNGSPSTNSDSDGS---STGSLPPTNTNVNTSTSEGATSGLIIPLTISGGSGPRPLNTVSQAPLPPGWEQRVDQHGRVYYVDHVEKRTTWDRPEPLPPGWERRVDNMGRIYYVDHFTRTTTWQRPTLESVRNYEQWQLQRSQLQGAMQQFNQRFIYGNQD-----LFATSQNKEFDPLGPLPPGWEKRTDSNGRVYFVNHNTRITQWEDPRSQGQ----------------LNEKPLPEGWEMRFTVDGIPYFVDHNRRATTYIDPRTGKSALDN---GPQIAYVRDFKAKVQYFRFWCQQLAMPQHIKITVTRKTLFEDSFQQIMSFSPQDLRRRLWVIFPGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFRFIGRFIAMALFHGKFIDTGFSLPFYKRILNKPVGLKDLESIDPEFYNSLIWVKENNIEECGLEMYFSVDKEILGEIKSHDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGFNEILPQQYLQYFDAKELEVLLCGMQEIDLNDWQRHAIYRHYTRTSKQIMWFWQFVKEIDNEKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKVGKENWLPRSHTCFNRLDLPPYKSYEQLKEKLLFAIEETEGFGQE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K9T1-1", "uniprot_id": "A0A0G2K9T1_RAT", "id": "A0A0G2K9T1-1", "name": "E3 ubiquitin-protein ligase", "aln": "MSD--------------SAPQLDSMGSLTMKS-----------------QLQITVISAKLKENKKNWFGPSPYVEVTVDGQSK-KTEKCNNTNSPKWKQPLTV-IVTPMSKLCFRVWSHQTLKS--DVLLGTAGLDIYETLKSNN--MKLEEVVMTLQLVGDKEPTET-MGDLSVCLDGLQVEAEVVTNGETSCSEG-----------------------------------------ATQNDAGCRPKDETRVSTNGSEDPEV-----AASGENKR---------------ANGNNSPSLSNG--GFKPSRPPRPSRPPPPTPRRPAS-VNGSPSTNSDSDGS---STGSLPPTNTNVNSSASEGAASGLIIPLTISGGSGPRPLNTVSQAPLPPGWEQRVDQHGRVYYVDHVEKRTTWDRPEPLPPGWERRVDNMGRIYYVDHFTRTTTWQRPTLESVRNYEQWQLQRSQLQGAMQQFNQRFIFGNQD-----LFATSQNKEFDPLGPLPPGWEKRTDSNGRVYFVNHNTRITQWEDPRSQGQ----------------LNEKPLPEGWEMRFTVDGIPYFVDHNRRATTYIDPRTGKSALDN---GPQIAYVRDFKAKVQYFRFWCQQLAMPQHIKITVTRKTLFEDSFQQIMSFSPQDLRRRLWVIFPGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFRFIGRFIAMALFHGKFIDTGFSLPFYKRILNKPVGLKDLESIDPEFYNSLIWVKENNIEECGLEMYFSVDKEILGEIKSHDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGFNEILPQQYLQYFDAKELEVLLCGMQEIDLNDWQRHAIYRHYTRTSKQIVWFWQFVKEIDNEKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKVGKENWLPRSHTCFNRLDLPPYKSYEQLKEKLLFAIEETEGFGQE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96J02-1", "uniprot_id": "ITCH_HUMAN", "id": "Q96J02-1", "name": "E3 ubiquitin-protein ligase Itchy homolog", "aln": "MSD--------------SGSQLGSMGSLTMKS-----------------QLQITVISAKLKENKKNWFGPSPYVEVTVDGQSK-KTEKCNNTNSPKWKQPLTV-IVTPVSKLHFRVWSHQTLKS--DVLLGTAALDIYETLKSNN--MKLEEVVVTLQLGGDKEPTET-IGDLSICLDGLQLESEVVTNGETTCSENGVSLCLPRLECNSAISAHCNLCLPGLSDSPISASRVAGFTGASQNDDGSRSKDETRVSTNGSDDPED-----AGAGENRR---------------VSGNNSPSLSNG--GFKPSRPPRPSRPPPPTPRRPAS-VNGSPSATSESDGS---STGSLPPTNTNTN--TSEGATSGLIIPLTISGGSGPRPLNPVTQAPLPPGWEQRVDQHGRVYYVDHVEKRTTWDRPEPLPPGWERRVDNMGRIYYVDHFTRTTTWQRPTLESVRNYEQWQLQRSQLQGAMQQFNQRFIYGNQD-----LFATSQSKEFDPLGPLPPGWEKRTDSNGRVYFVNHNTRITQWEDPRSQGQ----------------LNEKPLPEGWEMRFTVDGIPYFVDHNRRTTTYIDPRTGKSALDN---GPQIAYVRDFKAKVQYFRFWCQQLAMPQHIKITVTRKTLFEDSFQQIMSFSPQDLRRRLWVIFPGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFRFIGRFIAMALFHGKFIDTGFSLPFYKRILNKPVGLKDLESIDPEFYNSLIWVKENNIEECDLEMYFSVDKEILGEIKSHDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGFNEILPQQYLQYFDAKELEVLLCGMQEIDLNDWQRHAIYRHYARTSKQIMWFWQFVKEIDNEKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKVGKENWLPRSHTCFNRLDLPPYKSYEQLKEKLLFAIEETEGFGQE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Y0H4-1", "uniprot_id": "SUDX_DROME", "id": "Q9Y0H4-1", "name": "E3 ubiquitin-protein ligase Su(dx)", "aln": "MADGNGLPAGAASGGMEAGQTVNGAGSASPTPTSSSGAGASGSANQGYHQLSVTIEEASLRNN--GFLKPNPYVELLIDSKSKRKTDLVKNSYLPKWNEEFTV-LITPNSTLHFKVLDHSSFRK--DAMLGERIINLAHILQHYNGRCEFLELTIDLFVTSKSDNRQTKSGELVAILNGLKLDMSKLQIQPVAGQQNGN---------------------PPVQAVNPSVVSDAAAGRSCMIYGGVRARMRLRSSSGNSNGGETRSPLPNGGGDHRRSTQAPPVWEQQQQQSQNQQQPLRMVNGSGAAVPQTAPYPQQPPAPALARPLTQVYGALPENTQPAAVYLPAGGGAAVGPPGVAGPPIEQPGVGLPVSQSTDPQLQTQPAD---DEPLPAGWEIRLDQYGRRYYVDHNTRSTYWEKPTPLPPGWEIRKDGRGRVYYVDHNTRKTTWQRPNSERLMHFQHWQGQR---AHVVSQGNQRYLYSQQQQQPTAVTAQVTQDDEDALGPLPDGWEKKIQSDNRVYFVNHKNRTTQWEDPRTQGQEVSL------------INEGPLPPGWEIRYTAAGERFFVDHNTRRTTFEDPRPGAPKGAKGVYGVPRAYERSFRWKLSQFRYLCQSNALPSHIKITVTRQTLFEDSYHQIMRLPAYELRRRLYIIFRGEEGLDYGGVSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLQYFKFIGRFIAMALYHGRFIYSGFTMPFYKRMLNKKLTIKDIETIDPEFYNSLIWVKDNNIDECGLELWFSVDFEVLGQIIHHELKENGEKERVTEENKEEYITLMTEWRMTRGIEQQTKTFLEGFNEVVPLEWLKYFDERELELILCGMQDVDVEDWQRNTIYRHYNRNSKQVVWFWQFVRETDNEKRARLLQFVTGTCRVPVGGFAELMGSNGPQRFCIEKVGKETWLPRSHTCFNRLDLPPYKSYDQLVEKLTFAIEETEGFCQE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39940-1", "uniprot_id": "RSP5_YEAST", "id": "P39940-1", "name": "E3 ubiquitin-protein ligase RSP5", "aln": "------------------------MPS----------------------SISVKLVAAESLYKRDVFRSPDPFAVLTIDGYQTKSTSAAKKTLNPYWNETFKFDDINENSILTIQVFDQKKFKKKDQGFLGVVNVRVGDVLGHLD---------EDTATSSGRPREETITRDLKKSNDGMAVSGRLIVVLSKLPSSS--------------------------------------------PHSQAPSGHTASSSTNTSSTTRT-----------------------------NGHSTSSTRNH-------STSHPSRGTAQAVESTLQ------------------SGTTAATNTATTSHRSTNSTSSATRQYSSFEDQYG----------RLPPGWERRTDNFGRTYYVDHNTRTTTWKRPTLDQTEAERGNQLNANTELERRQHRGRTLPGGSSDNSSVTVQVGGGS----------NIPPVNGAAA-----AAFAATGGTTSGLGELPSGWEQRFTPEGRAYFVDHNTRTTTWVDPRRQQYIRTYGPTNTTIQQQPVSQLGPLPSGWEMRLTNTARVYFVDHNTKTTTWDDPRLPSSLDQN-----VPQYKRDFRRKVIYFRSQPALRILPGQCHIKVRRKNIFEDAYQEIMRQTPEDLKKRLMIKFDGEEGLDYGGVSREFFFLLSHEMFNPFYCLFEYSAYDNYTIQINPNSGINPEHLNYFKFIGRVVGLGVFHRRFLDAFFVGALYKMMLRKKVVLQDMEGVDAEVYNSLNWMLENSIDGV-LDLTFSADDERFGEVVTVDLKPDGRNIEVTDGNKKEYVELYTQWRIVDRVQEQFKAFMDGFNELIPEDLVTVFDERELELLIGGIAEIDIEDWKKHTDYRGYQESDEVIQWFWKCVSEWDNEQRARLLQFTTGTSRIPVNGFKDLQGSDGPRRFTIEKAGEVQQLPKSHTCFNRVDLPQYVDYDSMKQKLTLAVEETIGFGQE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .:.:.: *. : : *.*:. : :*. .. .*. ::: * *:: :.. :. * * ::* .:..::. : :** : : . * : . :* :* :*: :. : ... . *:. *. . . :.. * .. *.: .. : . : . . . . : . . : . **.*** * *:.** ***** : * *.:* . * : .. : * * . : : * : . . ** ** ***:: .:.*.***:*:.* * * *** * : *** ***:* * . :***** : **: *** . : * *.*: *: ** :* : :*.* *:.:***::::** .. :*::** : * **********:**:*******::**:******: :** :**** * :**:**:**:****.:.:.::* :*: : * .:** :*.* : ::*:* :*.*.**** *: :*.*: *:: **.* * :*:: :** :* : **: **:**: : ::**: :::* ::*::****::* : : ** :***::: *: ::*::**:::: ** * ...: : ***: * * ***:* *****.***.*:**.** :* **:**::* ***.*: **:*******:*** * .*:.: :** :*:*** ** **", "identical_positions": 252, "similar_positions": 239, "identity": "25.38%" }, { "cls_id": "homologset.agr.MGI:1202304", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P13255-1", "uniprot_id": "GNMT_RAT", "id": "P13255-1", "name": "Glycine N-methyltransferase", "aln": "---MVDSVYRTRSLGVAAEGIPDQYADGEAARVWQLYIGDTRSRTAEYKAWLLGLLRQHGCHRVLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRKEPAFDKWVIEEANWLTLDKDVPA--GDGFDAVICLGNSFAHLPDSKGDQSEHRLALKNIASMVRPGGLLVIDHRNYDYILSTGCAPPGKNIYYKSDLTKDITTSVLTVNNKAHMVTLDYTVQVPGAGRDGAPGFSKFRLSYYPHCLASFTELVQEAFGGRCQHSVLGDFKPYRPGQAYVPCYFIHVLKKTG-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QXF8-1", "uniprot_id": "GNMT_MOUSE", "id": "Q9QXF8-1", "name": "Glycine N-methyltransferase", "aln": "---MVDSVYRTRSLGVAAEGLPDQYADGEAARVWQLYIGDTRSRTAEYKAWLLGLLRQHGCHRVLDVACGTGVDSIMLVEEGFSVMSVDASDKMLKYALKERWNRRKEPSFDNWVIEEANWLTLDKDVLS--GDGFDAVICLGNSFAHLPDCKGDQSEHRLALKNIASMVRPGGLLVIDHRNYDYILSTGCAPPGKNIYYKSDLTKDITTSVLTVNNKAHMVTLDYTVQVPGTGRDGSPGFSKFRLSYYPHCLASFTELVRAAFGGRCQHSVLGDFKPYKPGQAYVPCYFIHVLKKTD-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14749-1", "uniprot_id": "GNMT_HUMAN", "id": "Q14749-1", "name": "Glycine N-methyltransferase", "aln": "---MVDSVYRTRSLGVAAEGLPDQYADGEAARVWQLYIGDTRSRTAEYKAWLLGLLRQHGCQRVLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRHEPAFDKWVIEEANWMTLDKDVPQSAEGGFDAVICLGNSFAHLPDCKGDQSEHRLALKNIASMVRAGGLLVIDHRNYDHILSTGCAPPGKNIYYKSDLTKDVTTSVLIVNNKAHMVTLDYTVQVPGAGQDGSPGLSKFRLSYYPHCLASFTELLQAAFGGKCQHSVLGDFKPYKPGQTYIPCYFIHVLKRTD-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VG42-1", "uniprot_id": "Q9VG42_DROME", "id": "Q9VG42-1", "name": "Glycine N-methyltransferase", "aln": "MTTSADSVFVARSDGISAEGVRDQYADGKAAKVWEIFIGDKNSRTDNYKNFLIDMLRNKGCKRVLDVACGTGVDSLMLVEEGFEVVSVDASDKMLKYALKERWARRNEAAFDKWVIEEANWLTLYDDIQEHIQDGFDAVICLGNSFAHLMDGFGDQREHKQAIGNFEKCLKPGGVLLIDHRNYDNILETG-ATPAKSIYYNTSHTADIKTSVLFYCGKPALVSMDYLIA-------GNKLTSEFRLSYYPHGLKRFQEILAEIFSAKAKHQLYGDFKEMS--QVKNPAFYIHLIEKPQV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .***: :** *::***: ******:**:**:::***..*** :** :*:.:**::**:*************:*******.* ***************** **:*.:**:********:** .*: .*************** * *** **: *: *: . ::.**:*:******* **.** *.*.*.***::. * *:.**** .*. :*::** : * *:******** * * *:: *..:.:*.: **** *. *.::**::::. ", "identical_positions": 162, "similar_positions": 74, "identity": "54.18%" }, { "cls_id": "homologset.agr.MGI:1202305", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B1WC45-1", "uniprot_id": "B1WC45_RAT", "id": "B1WC45-1", "name": "Vacuolar protein sorting-associated protein 72 homolog", "aln": "--------------MSLAGGRAPRKTAGNRLSGLLEAE----EEDEFYQTTYGG------------FTEESGDDEYQGDQSDTEDEVDSD------------------------FDIDEGDEPSSDGEAEEPRRKRR----VVTKAYKEPLKSLR----PRKVSTPASSSQKAREEKTLLPLELQDDGSDSRKSMRQSTAEHTRQTFLRVQERQ------GQSRRRKGPHCERPL-TQEELLREAKITEELNLRSLETYERLEADKK-----------------------------------------------KQVHKKRKCPG----------------------------------------------------------------------------------------------------------------------PIITYHSVTVPLVGEPGPKEENVDVEGLDPAPTSSALTAHAGTGP----------------------------------------------------------------------------------------------AVPPPHCSRTFITFS-----------------------------------DDATFEEWFPQGR--PPKVPVREV-----------------------------------------------------CPVTHRPALYRDPVTDIPYATARAFKIIREAYKKYITAHGLPPTASALGPGPPPPEPLPGAGPRALRQKIVIK-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q62481-1", "uniprot_id": "VPS72_MOUSE", "id": "Q62481-1", "name": "Vacuolar protein sorting-associated protein 72 homolog", "aln": "--------------MSLAGGRAPRKTAGNRLSGLLEAE----EEDEFYQTTYGG------------FTEESGDDEYQGDQSDTEDEVDSD------------------------FDIDEGDEPSSDGEAEEPRRKRR----VVTKAYKEPLKSLR----PRKVSTPASSSQKAREEKTLLPLELQDDGSDSRKSMRQSTAEHTRQTFLRVQERQ------GQSRRRKGPHCERPL-TQEELLREAKITEELNLRSLETYERLEADKK-----------------------------------------------KQVHKKRKCPG----------------------------------------------------------------------------------------------------------------------PIITYHSVTVPLVGEPGPKEENVDVEGLDPAPTASALAPHAGTGTGA------------------------------------------------------------------------------------------AAATPPAHCSRTFITFS-----------------------------------DDATFEEWFPQGR--PPKVPVREV-----------------------------------------------------CPVTHRPALYRDPVTDIPYATARAFKIIREAYKKYITAHGLPPTASALGPGPPPPEPLPGSGPRALRQKIVIK-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15906-1", "uniprot_id": "VPS72_HUMAN", "id": "Q15906-1", "name": "Vacuolar protein sorting-associated protein 72 homolog", "aln": "--------------MSLAGGRAPRKTAGNRLSGLLEAE----EEDEFYQTTYGG------------FTEESGDDEYQGDQSDTEDEVDSD------------------------FDIDEGDEPSSDGEAEEPRRKRR----VVTKAYKEPLKSLR----PRKVNTPAGSSQKAREEKALLPLELQDDGSDSRKSMRQSTAEHTRQTFLRVQERQ------GQSRRRKGPHCERPL-TQEELLREAKITEELNLRSLETYERLEADKK-----------------------------------------------KQVHKKRKCPG----------------------------------------------------------------------------------------------------------------------PIITYHSVTVPLVGEPGPKEENVDIEGLDPAPSVSALTPHAGTGP----------------------------------------------------------------------------------------------VNPPARCSRTFITFS-----------------------------------DDATFEEWFPQGR--PPKVPVREV-----------------------------------------------------CPVTHRPALYRDPVTDIPYATARAFKIIREAYKKYITAHGLPPTASALGPGPPPPEPLPGSGPRALRQKIVIK-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AJ70-1", "uniprot_id": "A0A8M3AJ70_DANRE", "id": "A0A8M3AJ70-1", "name": "Vacuolar protein sorting-associated protein 72 homolog", "aln": "--------------MSLAFSRAPRKTAGNRMSRLLDAE----EEDEFYKTTYGG------------FHDESGDEEYKGDLTETEDEVDSD------------------------FDIDEGDEPDSEQEEDGPRRKSR----VVTKAYKEPVKVVRQKPKQRKLAELPRRTDKTKIDKYNP-PELQDDIN--RKSVRQSTTEHTRLTYLRLQERQ------VAPRRRKGTRHERPL-TQAELLAEAKVTAEINLRSLENYERLEADKK-----------------------------------------------RQVHMKRQCVG----------------------------------------------------------------------------------------------------------------------SVIRYHSVLMPLVSDVTLKEENVDVEGLDQDAQQNPHLPQALSQSESTLS-------------------------------------------------------------------------------AAPGVPFTNTAAVNTKCSRTYITFS-----------------------------------DDESFQRVFPQSP--APRVPVQEV-----------------------------------------------------CPVTHKPALYRDPITDIPYANVQAFRIIREAYKKYVAAHGLPCTGPSTPADTTA---------KSLKQKIIIKQAI----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q1L8X4-1", "uniprot_id": "Q1L8X4_DANRE", "id": "Q1L8X4-1", "name": "Vacuolar protein sorting-associated protein 72 homolog", "aln": "--------------MSLANSREQRSTAGNRMSKLLDAE----EEDEFYKTTYGG------------FNDESGDDEYHGDHSDTEDEVDSD------------------------FDIDEGDEPDSGQEEDAPKRKSR----VVTKAYKEPLKVS--KPKVKRVSEELK-PERPRVERRTV-RDELQDLGDIRKSVRKSTSEHTRKTNERLQERQQ-----EAPRKRKGAQSERVL-TQDELLDEAKLTAESNLRSLENYERLEADKK-----------------------------------------------KQVHKKRRFEG----------------------------------------------------------------------------------------------------------------------PMIRYHSVLMPLLPDTHLKEENVDVEGLDQDT------PQATPTSSS------------------------------------------------------------------------------------------STQGAGSLCSRTYITFS-----------------------------------DDEAFSSAFPSAARCTPTHPVQEV-----------------------------------------------------CPVTHKPALYRDPVTDIPYANARAFRIIREAYQKYIAAHGFPNASGSFSANTDASDSP--ANLKSARPKAVLKQSAAAT-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VKM6-1", "uniprot_id": "VPS72_DROME", "id": "Q9VKM6-1", "name": "Vacuolar protein sorting-associated protein 72 homolog", "aln": "----------------MAASRSRRNNAGNKIAHLLNEE----EEDDFYKTSYGG------------FQEDEEDKEYE-QKDEEEDVVDSD------------------------FSIDENDEPVSDQEEAPEKKRKRG--VVNTKAYKETKPAVK---KETKATPALHKKRPGGGVTKRRPRPRFTVLDSGRKSIRTSTAIKTQATKIRLKELDD-----ARKRKKKKVRVEDYMPTQEELLEEAKITEEENTKSLEKFQKMELEKK-----------------------------------------------KSRPTKRTFSG----------------------------------------------------------------------------------------------------------------------PTIRYHSLTMPAMRKPT-RGANPAVDSKDLAG----------------------------------------------------------------------------------------------------------------KCERTFVTIENDF--------------------------------NDKVFQSLFRHKA---PPKASNGI-----------------------------------------------------CPITRLPARYFDPITQQPYYSIQAFKILREAYYMQLEQQGGGSEQPELAKWLEWRKLVKENRLKASAAASKNGDN-----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q03388-1", "uniprot_id": "VPS72_YEAST", "id": "Q03388-1", "name": "Vacuolar protein sorting-associated protein 72", "aln": "MSDEGADKSLDTNTEFIIQTRSRRSNAGNKLQKLLEQELRDIESTKRQISSYKNGNDDEEDEIGLLFQEDEDDEDFEMMAKDDDDEGEEKEDETQSIRKEPSQASSEQAADDLMFSSSESEDSSNENDEDAEEKEIRRQELLSRKKRNKRLQKGPVVIKKQKPKPKSGEAIPRSHHTHEQLNAETLLLNTRRTSKRSSVMENTMKVYEKLSKAEKKRKIIQERIRKHKEQESQHMLTQEERLRIAKETEKLNILSLDKFKEQEVWKKENRLALQKRQKQKFQPNETILQFLSTAWLMTPAMELEDRKYWQEQLNKRDKKKKKYPRKPKKNLNLGKQDASDDKKRESEESIKNDGDVNSLGENSSSVHNQKRIEETSTNDTVEGESSPDAAVSRVNSDELKPTALPDVTLDAIANKQSTVDEAPNSQPQKNIITNEQKITNVGEPIQNLHNEEIKDEMVSALESRENTFENSSPAAQVVSQRDNSATPTPSNSTGTEDTILISPDTDIKGEPEPCLKTEGIENLSHNVPQETKSNTDVSFLKQVTFTDHPQVAIIDTEESPSKKDTANVDESSAENSLSTQTYEGPEQLTSRNFVTLYDFPNAPPNLKDFNTNLFGDRWSYTNGLSATQRPQDMKTVFHSILPSPPQSSVPSPTVDISLDLSALANFPSFGEYDKKIVHQINTEINKDLEIKIKTQPPTGVFLANGIRKKCLITNKECQYFDPRTGVPYSDVEAYKIIQRIQDPISKEEGRSDIKRDETTNEDSDDQVRFKWFGFKNGGIYLDLSQRPAKGVPEGF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * *..***:: **: * *. . ::* . * ::. *.::. : :* :.. *. .*.::. . : .:. * : * :: : . *.* * *. :* . ::.: : ::: : . : ** * * ** * : * **:.::. * ** : *: . *. : . : .:. . .*.::*: . * : . : * :*. . * ** * ** .*::*::. .* ", "identical_positions": 51, "similar_positions": 90, "identity": "6.42%" }, { "cls_id": "homologset.agr.MGI:1202306", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O55241-1", "uniprot_id": "OREX_MOUSE", "id": "O55241-1", "name": "Hypocretin neuropeptide precursor", "aln": "MNFPSTKVPWAAVT-LLLLLLLPPALLSLGVDAQPLPDCCRQKTCSCRLYELLHGAGNHAAGILTLGKRRPGPPGLQGRLQRLLQANGNHAAGILTMGRRAGAELEPHPCSGRGCPTVTTTALAPRGGSGV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O55232-1", "uniprot_id": "OREX_RAT", "id": "O55232-1", "name": "Hypocretin neuropeptide precursor", "aln": "MNLPSTKVPWAAVT-LLLLLLLPPALLSLGVDAQPLPDCCRQKTCSCRLYELLHGAGNHAAGILTLGKRRPGPPGLQGRLQRLLQANGNHAAGILTMGRRAGAELEPYPCPGRRCPTATATALAPRGGSRV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O43612-1", "uniprot_id": "OREX_HUMAN", "id": "O43612-1", "name": "Hypocretin neuropeptide precursor", "aln": "MNLPSTKVSWAAVTLLLLLLLLPPALLSSGAAAQPLPDCCRQKTCSCRLYELLHGAGNHAAGILTLGKRRSGPPGLQGRLQRLLQASGNHAAGILTMGRRAGAEPAPRPCLGRRCSAPAAASVAPGGQSGI", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:*****.***** ************* *. **************************************.***************.***************** * ** ** *.: :::::** * * :", "identical_positions": 106, "similar_positions": 13, "identity": "80.92%" }, { "cls_id": "homologset.agr.MGI:1202307", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LME7-1", "uniprot_id": "F1LME7_RAT", "id": "F1LME7-1", "name": "Pleckstrin homology-like domain family A member 2", "aln": "MFARGGRRRWPGLGKNPWVYDPGAQESSITPSRGGVLIRPTPGPRPSAERAHLVQAFEMASKTVKTSDEILCEGELEKRSDSLFQVWKKKRCVLTADRLRLFSGNS--DRPKELYFHSILKVDCVEHTSKYVYFTIVTNFYKEIDFRCTVES-CWNAAITMALIDYQNRRALEEFRRFRYQHS-----------ASETQSSPGGRRALGP-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O08969-1", "uniprot_id": "PHLA2_MOUSE", "id": "O08969-1", "name": "Pleckstrin homology-like domain family A member 2", "aln": "----------------------------------------------------MASKIVMSSKTVKTSDEILCEGELEKRSDSLFQVWKKKRCVLTADRLRLFSGKT--SPAKELFFHSILKVDCVEHTSKYVYFTIVTNYYKEIDFRCTVES-CWNAAITMALIDFQNRRALQDFPRYRYQRS-----------ESEMPSEPGEQSALGP-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q53GA4-1", "uniprot_id": "PHLA2_HUMAN", "id": "Q53GA4-1", "name": "Pleckstrin homology-like domain family A member 2", "aln": "---------------------------------------------------------------MKSPDEVLREGELEKRSDSLFQLWKKKRGVLTSDRLSLFPASPR-ARPKELRFHSILKVDCVERTGKYVYFTIVTTDHKEIDFRCAGES-CWNAAIALALIDFQNRRALQDFRSRQERTAPAAPAEDAVAAAAAAPSEPSEPSRPSPQPKPRTP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q503L1-1", "uniprot_id": "PHLA2_DANRE", "id": "Q503L1-1", "name": "Pleckstrin homology-like domain family A member 2", "aln": "-------------------------------------------------------------MTGSDISHILKEGELEKRSDNLLQFWKRKTCVLTTDSLNIYTDQQKKNKSKELKLQSIKKVDCVEHTGKFVYFTIVTTDNKEIDFRCSDEKNCWNAVIAIALVNFQNRKAIQGFKTQKESEN-----------TSLGQQERCMARAP---------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . ..:* *********.*:*.**:* ***:* * ::. . .*** ::** ******:*.*:*******. *******: *. ****.*::**:::***:*:: * : : .. ", "identical_positions": 60, "similar_positions": 35, "identity": "27.65%" }, { "cls_id": "homologset.agr.MGI:1202384", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q16531-1", "uniprot_id": "DDB1_HUMAN", "id": "Q16531-1", "name": "DNA damage-binding protein 1", "aln": "MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRE-TDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSS---SKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3U1J4-1", "uniprot_id": "DDB1_MOUSE", "id": "Q3U1J4-1", "name": "DNA damage-binding protein 1", "aln": "MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPGRE-TDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQGKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDSSGGTTALRPSASTQALSSSVSS---SKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGEASTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9ESW0-1", "uniprot_id": "DDB1_RAT", "id": "Q9ESW0-1", "name": "DNA damage-binding protein 1", "aln": "MSYNYVVTAQKPTAVNGCVTGHFTSAEDINLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQPVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRE-TDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPRAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDVTPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANTSTLTIGTMNEIQKLHIRTVPIYESPRKICYQEVSQCFGVLSTRIEVQDTSGGTTALRPSASTQALSSSVSS---SKLFSSSAAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSGGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLLGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9XYZ5-1", "uniprot_id": "DDB1_DROME", "id": "Q9XYZ5-1", "name": "DNA damage-binding protein 1", "aln": "MSHHYVVTAQKPTAVVACLTGNFTSPTDLNLIIARNNQVEIDLVTPEGLRPLKEININGTIAVMRHFRPPDSNKDLLFILTRRYNVMILEARMVNDVITVVTKANGNVSDSVGIPSEGGVIAAIDPKARVIGMCLYQGLFTIIPMDKDASELKATNLRMDELNVYDVEFLHGCLNPTVIVIHKDSDGRHVKSHEINLRDKEFMKIAWKQDNVETEATMLIPVPSPIGGVIVIGRESIVYHDGSNYHAVAPLTFRQSTINCYARVSSNGLRYLLGNMDGQLYMLFLGTAETSKG-VTVKDIKVEQLGEISIPECITYLDNGFLYIGARHGDSQLVRLNSEAID-GSYVVPVENFTNLAPILDIAVVDLDRQGQGQIITCSGSFKDGSLRIIRIGIGIQEHACIDLPGIKGMWSLKVGVDESPYENTLVLAFVGHTRILTLSGEEVEETEIPGFASDLQTFLCSNVDYDQLIQVTSDSVRLVSSATKALVAEWRPTGDRTIGVVSCNTTQILVASACDIFYIVIEDGSLREQSRRTLAYEVACLDITPLDETQKKSDLVAVGLWTDISAVILSLPDLETIYTEKLSGEIIPRSILMTTFEGIHYLLCALGDGSMYYFIMDQTTGQLTDKKKVTLGTQPTTLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNHMCSLNAQAYPDSLALANKNAVILGTIDEIQKLHIRTVPLGEGPRRIAYQESSQTFAVSTLRIDVHGR-GGAKPLRNSASTQAQNITCSSNFLPKPGGGNSTAANAEVGQEIDVHNLLVIDQNTFEVLHAHQFVAPETISSLMSAKLGDDPNTYYVVATSLVIPEEPEPKVGRIIIFHYHENKLTQVAETKVDGTCYALVEFNGKVLAGIGSFVRLYEWTNEKELRMECNIQNMIAALFLKAKGDFILVGDLMRSITLLQHKQMEGIFVEIARDCEPKWMRAVEILDDDTFLGSETNGNLFVCQKDSAATTDEERQLLPELARFHLGDTVNVFRHGSLVMQNVGERTTPINGCVLYGTCNGAIGIVTQIPQDFYDFLHGLEERLKKIIKSVGKIEHTYYRNFQINSKVEPSEGFIDGDLIESFLDLSRDKMRDAVQGLELTLN-GERKSADVEDVIKIVEDLTRMH", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**::*********** .*:**:***. *:**:**:*.::** :**.*****:**:.: *.****. *** ...******** :**. *** : .: * ::*:*:***.* :* *** *:*. ***:.*:**: **:***.:**:*:* .**** *:*::**:* **:**:** **: .:::*.:*****::*:.**:*** * .***:***:**:*:*.**.*:**.*:**:***.**:*.:* *:** ::**** *: **..** *****:*:*:*:**:* . * .* **:**::** *** **.**:******.:::*:* **** *:** :: : *****.:*.****.**:*:.****:******::****:**:******* ****:***.********:*.*: . ... ::****:***:**:* *.********: **..* ***:*.** ::****:** ******. .****:**: . :.*.*.***::*::** . ::*: *. .**: *: : :******:***.::: * * *:******** **.**.:* ::.* *.**************. **********:::** :: ** *:*:**********.****************************************:**.**::.*********..:: :**::***********: *.**:*.*** ** *.* : **:*:. **:..** ****** . : ** .* ...::. ::..*:*::*****:***:**********: * **:*.***.*****::*.*::* ***.*** ***::*:* .** ***.:*.*: *::******:**.*.* *******.***** *** * * **:**:*************: ** :* *** * ***** :*:** ********.***:*. ****************** * *:. ****: **** ********:** :** :*.** ** ** **:**.:.:.:*::* .:::**:*:*********:::*.*: : *.**: *************:** **::.* .*: . * ::.* .:*:**:**:***:*", "identical_positions": 690, "similar_positions": 307, "identity": "60.31%" }, { "cls_id": "homologset.agr.MGI:1202386", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q499U4-1", "uniprot_id": "DRC4_RAT", "id": "Q499U4-1", "name": "Dynein regulatory complex subunit 4", "aln": "MAPKRRGKKGKAKGNAVVDGVAPEDMSKEQVEEHVARIREELDREREERNYFQLERDKIHTFWEITRRQLEEKKAELRNKDREMEEAEERHQVEIKVYKQKVKHLLYEHQNNLAEVKTEGTVVMKLAQKEHRAQEGALRKDMRVLKVELKEQELANEVVIKNLRLKQAEEITKMRNDFERQVREIEAKYDKKMKMLRDELDLRRKTEIHEVEERKNGQISTLMQRHEEAFTDIKNYYNDITLNNLALINSLKEQMEDMRKKEEYLEREMAEVSLQNKRLAEPLQRAKEEMSEMQKRLGNHERDKQILACTKARLKVTEKELKDLKWEHEILEQRFIKVQQEREELYRKFTAAIQEVQQKTGFKNLVLERKLQALNAAVEKREVQFNEVLAASNLD-PTALTLVSRKLEDVLESKNTTIKDLQYELARVCKAHNDLLRTYEAKLLAFGIPLDNVGFKPLETAVIGQTLGQGPAGLVGAPT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60779-1", "uniprot_id": "DRC4_MOUSE", "id": "Q60779-1", "name": "Dynein regulatory complex subunit 4", "aln": "MAPKKKGKKGKAKGTAIVDGVAPEDMTKEQVEEHVARIREELDREREERNYFQLERDKIHTFWEITRRQLEEKKAELRNKDREMEEAEERHQVEIKVYKQKVKHLLYEHQNNLAEVKAEGTVVMKLAQKEHRTQEGALRKDMRVLKVELKEQELANEVVIKNLCLKQAEEITKMRNDFERQVREIEAKYDKKMKMLRDELDLRRKTEIHEVEERKNGQISTLMQRHEEAFTDIKNYYNDITLNNLALINSLKEQMEDMRKKEEHMEREMAEVTLQNRRLADPLQKAKDEMNEMQKRLGNHERDKQILVCTKARLKVAERELKDLKWEHEVLEQRFIKVQQEREELYRKFADAIQEVQQKTGFKNLLLERKLQALNAAVEKREVQFNEVLAASNLD-PTALTLVSRKLEDVLESKNTTIKDLQYELARVCKAHNDLLRTYEAKLLAFGIPLDNVGFKPLETAVIGQTLGQGPAGLVGAPT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95995-1", "uniprot_id": "DRC4_HUMAN", "id": "O95995-1", "name": "Dynein regulatory complex subunit 4", "aln": "MAPKKKGKKGKAKGTPIVDGLAPEDMSKEQVEEHVSRIREELDREREERNYFQLERDKIHTFWEITRRQLEEKKAELRNKDREMEEAEERHQVEIKVYKQKVKHLLYEHQNNLTEMKAEGTVVMKLAQKEHRIQESVLRKDMRALKVELKEQELASEVVVKNLRLKHTEEITRMRNDFERQVREIEAKYDKKMKMLRDELDLRRKTELHEVEERKNGQIHTLMQRHEEAFTDIKNYYNDITLNNLALINSLKEQMEDMRKKEDHLEREMAEVSGQNKRLADPLQKAREEMSEMQKQLANYERDKQILLCTKARLKVREKELKDLQWEHEVLEQRFTKVQQERDELYRKFTAAIQEVQQKTGFKNLVLERKLQALSAAVEKKEVQFNEVLAASNLD-PAALTLVSRKLEDVLESKNSTIKDLQYELAQVCKAHNDLLRTYEAKLLAFGIPLDNVGFKPLETAVIGQTLGQGPAGLVGTPT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QNW4-1", "uniprot_id": "DRC4_DANRE", "id": "F1QNW4-1", "name": "Dynein regulatory complex subunit 4", "aln": "MPPKRKSSP-KGKTPTVVDGLSTEEMSKEQLEEHIMRLREELDREREERNYFQLERDKIHTFWEITRRHLEENKCELRNRERELEEVEERHQVEIKVYKQKVKHLLYEQQNMLSELKAESIISTKLLQDEHADLEKEQWKDMRSLKLELKQQELSSENVLKRIHLKHDEETTDLRNDFARQVQEIGSKYEKRMQKLRQEEELRRKTEIHEIEERKNTHINMLMKNHEKAFRDIRNYFSDIVYKNLDLITSLKEELKEMKKNEEKRNKEMAEVLEQNKELKESSQKAKEQVAELQKQLANYEKDKSILTRSRARLKMSDREMKELKWELEVLEQRFSKVQLERDELYMKFTKAILEVQQKSGFKNLLLECKLNTLNDTLEKKEAQLSEVLSASNLD-PTTLSVVTHKLEEVLESKNHTIKDLQYEVARVCKAHNDLLKTSEAKLRAFGIPVEELCFEPLKSN--GQSVGQGPAMFVSSSN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8MT08-1", "uniprot_id": "DRC4_DROME", "id": "Q8MT08-1", "name": "Dynein regulatory complex subunit 4", "aln": "MPPKGKKGKKGKKLPVLIDGVDTSAMTRDQLEAFALRLKAEMDREREERNYFQLERDKIRTFWEITRQQLDETRYELQQKDKEIEATQDLADIDTKHVMQQMKHLQFENHNRLGEVRAEAMTQLKLAQEHHVLQENELQRDKRQLRRMLRERMEMSEMQLRQMEAHFNEKLLEQRITFERERKDNEMLHEEKMIEQKAKLDLFYGTQMFEVEERKNQQIKDLQDHHDLAFNDMKNYYNDITLNNLALIGSMKEQLEHLRKQAERSDRIAADTAAENRRLKEPLEHANIQLNEYRRKLEFYERDKQQLSRLKTRNTRLEKKVKGLTWEAETLILRNDSLVAEREGLKERFNDVIVELQQKTGLKNVLLERKIAALMREDEKRSIVLHETIATCAPNFAEKLTSLDERVGNIIDEKNKIILDLRYEVTKARKAHDDLLETYECKLKQYGVPTDELGFKPIRNRDQQQLYVCGPAGIITENK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.** : * ::**: .. *:::*:* . *:: *:*****************:*******::*:*.: **:::::*:* .:: ::: * *::*** :*::* * *:::*. ** *..* * :* * *: *::: .* ::.: : *: * * *: :: ::::* : : :* *::.*:***** :* * ..*: ** *::**:.**. :** ** *:**:::.::*: : :: *:. :*:.* :. ::*. :: * :::* :*:**. * ::* . ::::* * ** * * * .: **: * :* .* *:***:*:**::** *: :* **:. : *.:::. : . *: : .:: ::::.** * **:**:::. ***:***.* *.** :*:* ::: *:*:.. * *** :: .", "identical_positions": 155, "similar_positions": 168, "identity": "32.36%" }, { "cls_id": "homologset.agr.MGI:1202388", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q60780-1", "uniprot_id": "GAS7_MOUSE", "id": "Q60780-1", "name": "Growth arrest-specific protein 7", "aln": "-------------------------------------------------------MATALQKPGMVPPPPGEESQTVILPPGWHSYLSPQGRRYYVNTTTNETTWERP-SSSPGISASPAPHRSSLP--------TTVNGYHASGTPAHPPETAHMSLRKSTGDSQNLGSSSPGRKQ----------SKENTITINCVTFPHPD------------------------TMPEQQLLKPTEWSYCDYFWADKKDPQGNGTVAGFELLLQK----------QLKGKQMQKEMS--------EFIRERIKIEEEYAKNLAKLSQNSLAAQEEGSLGEAWAQVKKSLADEAEVHLKFS------------------------AKLHSEVEKPLMNFRENFKKDMKKCDHHIADLRKQLA-SRYASVEKARKALTERQKDLEMKTQQLEIKLSNKTEEDIKKARRKSTQAGDDLMRCVDLYN---------------QAQSKWFEEMVTTTLELERLEVERVEMIRQHLCQYTQLR-------------HETDMFNQSTVEPVDQLLRKVDPAK---------------------------------------------------------------------------------DRELWVREHKTGNIRPVDMEI-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O55148-1", "uniprot_id": "GAS7_RAT", "id": "O55148-1", "name": "Growth arrest-specific protein 7", "aln": "-------------------------------------------------------MATALQKPGMVPPPPGEESQTVILPPGWHSYLSPQGRRYYVNTTTNETTWERP-SSSPGISASPGPHRSSLP--------TTVNGYHASGTPAHPPETAHMSLRKSTGDSQNLGSSSPGRKQ----------SKENTITINCVTFPHPD------------------------TMPEQQLLKPTEWSYCDYFWADKKDPQGNGTVAGFELLLQK----------QLKGKQMQKEMS--------EFIRERIKIEEEYAKNLAKLSQNSLAAQEEGSLGEAWAQVKKSLADEAEVHLKFS------------------------AKLHSEVEKPLMNFRENFKKDMKKCDHHIADLRKQLGESRYASVEKARKALTERQKDLEMKTQQLEIKLSNKTEEDIKKARRKSTQAGDDLMRCVDLYN---------------QAQSKWFEEMVTTTLELERLEVERVEMIRQHLCQYTQLR-------------HETDMFNQSTVEPVDQLLRKVDPAK---------------------------------------------------------------------------------DRELWVREHKTGNIRPVDMEI-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O60861-3", "uniprot_id": "GAS7_HUMAN", "id": "O60861-3", "name": "Growth arrest-specific protein 7", "aln": "MSGARCRTLYPFSGERHGQGLRFAAGELITLLQVPDGGWWEGEKEDGLRGWFPASYVQLLEKPGMVPPPPGEESQTVILPPGWQSYLSPQGRRYYVNTTTNETTWERP-SSSPGIPASPGSHRSSLP--------PTVNGYHASGTPAHPPETAHMSVRKSTGDSQNLGSSSPSKKQ----------SKENTITINCVTFPHPD------------------------TMPEQQLLKPTEWSYCDYFWADKKDPQGNGTVAGFELLLQK----------QLKGKQMQKEMS--------EFIRERIKIEEDYAKNLAKLSQNSLASQEEGSLGEAWAQVKKSLADEAEVHLKFS------------------------AKLHSEVEKPLMNFRENFKKDMKKCDHHIADLRKQLA-SRYASVEKARKALTERQRDLEMKTQQLEIKLSNKTEEDIKKARRKSTQAGDDLMRCVDLYN---------------QAQSKWFEEMVTTTLELERLEVERVEMIRQHLCQYTQLR-------------HETDMFNQSTVEPVDQLLRKVDPAK---------------------------------------------------------------------------------DRELWVREHKTGNIRPVDMEI-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q05080-1", "uniprot_id": "CYK2_YEAST", "id": "Q05080-1", "name": "Cytokinesis protein 2", "aln": "----MSYSYEACFWDPNDNGVNILLGHISQGIRSCDSMILFFKQRSELEKDY---ARRLGAITGKLDKDIGTNMDYGKLNETFNVVLSVEKARAQSHSKQSEILFRQIYTDTKAFAANLQARYTTLSGKIERLRMDKFNKKKGCEVLQKKLQDAQIRFRDLQLNENNMIGAKRVEHNKRELLKWESNSQEYKVQLDVLKQEYKASQKFWIHEWAQLSCELQEMENARISFLQSKLQQFATSSMETYILEQTKMDMLTNHLNSFTAADEISTFSKENGTGRLKHKTSKGDMNSSANWAQMSSISTTSKKTESYMDNIRKLSSQLKETENKRKLASIDKYEKPLPSPEVTMATQFRNSTPVIRNETKVVANPTLSLRSSPVQLQSNVDDSVLRQKPDKPRPIVGEEQLKPDEDSKNPDEKGLMVHKRNQSLSSPSESSSSNPTDFSHIKKRQSMESMTTSVSSMANSIDDSQRFAKSWNSSNRKRKSMSHLQVPSSASSRSDDGGRTPNSAHNLNEDDYNTRRDTSTSTILFKPPVAVRGTSRGHTHRQSMIMQDSSNPIEDALYEMERIQSSSKPGTKTGNIMDERGVVRDRGITVTLPIVTSEGFPVIEYAKAMYPLIGNEAPGLANFHKGDYLLITEIVNKDWYKGEVYDNDRIDRNHRIGLIPYNFIQLLHQGL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* : * : : * :: ** : * ::. .* :.: :.: .:.*. .: ::*. ..* :.. . : : *:: .*. :.:*: .:. .:: *:* .: :: :. : :: :.:* : : * *: :.* .. : .* : :** * : :*. . * * *.* .*: ***.: :::: .*.. * : *. : :* .:*:*:*:..::. : : : : :: .* .: .: *.* .::*:. ... . :. ::. ..:: *.:..: . ::: ** * .. :* .: *. :: *. . ..*: : : *: . :: *. .*: *.: :*::: * ::: : *.: *:*: * * ::: ", "identical_positions": 62, "similar_positions": 180, "identity": "9.17%" }, { "cls_id": "homologset.agr.MGI:1202390", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BQC3-1", "uniprot_id": "IGDC3_MOUSE", "id": "Q8BQC3-1", "name": "Immunoglobulin superfamily DCC subclass member 3", "aln": "MAEPRTASPRRLPALRRPGFLPPLLPPPPPPLLLLLLLLPLPAPSLGLGHSAELAFSVEPNDDIANPGQPIVLGCKVEGTPP----VQVSWRKNGAELPEGTHTTLLANGSLLIHHFRLEQGGSPSDEGDYECVAQNRFGLLVSRKARLQAATMSDFHVH----PQAVTGEEGGVARFQCQIHGLPKPLITWEKNRVPIDTDDERYTLLPKGVLQITGLRAEDSGIFHCVASNIAS---VRVSHGARLTVSGSGSGTYKEPTILVG---PENLTLTVHQTAVLECVATGNPRPIVSWSRLDGRPIGVEGIQVLGTGNLIISDVTVQHSGVYVCAANRPGTRVRRTAQGRLVVQAPAEFVQHPQSISRPAGTTAMFTCQAQGEPPPHVTWLKNGQVLGAGGHVRLKNNNSTLSISGVGPEDEAIYQCVAENIAGSSQASARLTVLWAEGLPG---------------------PPRNVRAVSVSSTEVRVSWSEPLAHTKEIIGYVLHIRKAADSPKLEYQEAVS-----------KSTFQHLVRDLEPSTAYSFYIKAYTPRGASLASVP------TLASTLGEAPVPPPLSVRLLGSSSLQLLWKPWPRLAQHNG-GFKLFYRP-VSATSFTGPILLPGTVSSYNLSQLDPSTVYEVKLLAYNQH-GDGNATVRFVSLKGASERTALTPPCDCRKEDVTNHTSTTGIVIG-IHIGVTCIIFCVLFLLFGQRGRVLLCKDVENQLSPPQGPRSQRD-PGILALNGLSRGEGGQ-------------LSRDEKPVDAKELEQLFPTAGSAAQPGSTPT-DPAAPAPCEETQLSMVQLQGFNLVAG-----RTTEATSPCAGPGPVPAPQDIGPVPLSEGQT-QPPAVAAPQ-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZQ86-1", "uniprot_id": "D3ZQ86_RAT", "id": "D3ZQ86-1", "name": "Immunoglobulin superfamily DCC subclass member 3", "aln": "MAEPRTASPRRPPALRRPRLLPPLLPPLLPP--LLLLLLPLPVPSLGLGHSAELAFSVEPNDDIANLGQPIMLGCKVEGSPP----VQVSWRKNGAELPEDTHTTLLANGSLLIHHLRLEQGESPSDEGDYECVAQNRFGLLVSRKARIQVATMSDFHVH----PQAVMGEEGGVARFQCQIHGLPKPLITWEKNRVPIDTDDERYTLLPKGVLQITGLRAEDSGVFHCVASNMAS---VRVSHGARLTVSGSGSGTYKEPTILVG---PENLTLTVHQTAVLECVATGNPRPIVSWSRLDGRPIGVEGIQVLGTGNLIISDVTVQHSGVYVCAANRPGTRVRRTAQGRLVVQAPAEFVQHPQSISRPAGTTAMFTCQAQGEPPPHVTWLKNGQVLGAGGHVRLKNNNSTLSISGVGPEDEAIYQCVAENIAGSSQASARLTVLWAEGLPG---------------------PPRNVRAVSVSSTEVRVSWSEPLTHTKEIIGYVLHIRKAADSPKLEYQEAVS-----------KSTFQHLVRDLEPSTAYSFYIKAYTPRGASLASVP------TLASTLGEAPVPPPLSVRLLGSSSLQLLWKPWPRLAQHNG-GFKLFYRP-ASAASFTGPILLPGTVSSYNLSQLDPSTVYEVKLLAYNQN-GDGNATVRFVSLKGASERTALTPPCDCRKEEVTNHTSTTGIVIG-IHIGVTCIIFCVLFLLFGQRGRVLLCKDVENQLSPPQGPRSQRD-PGILTLNGVNRGEGGQ-------------LGRDEKHVDAKELEQLFPTTASAGQPGSRST-DPTAPTPYEETQLSMVQLQDFNLAAG-----RTTETMSSCAGPGPVPASQDVGLGLLSDRQTAQPLAVPAPQ-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8IVU1-1", "uniprot_id": "IGDC3_HUMAN", "id": "Q8IVU1-1", "name": "Immunoglobulin superfamily DCC subclass member 3", "aln": "MAVQRAASPRRPPAPLWPRLLLPLL------------LLLLPAPSEGLGHSAELAFAVEPSDDVAVPGQPIVLDCRVEGTPP----VRITWRKNGVELPESTHSTLLANGSLMIRHFRLEPGGSPSDEGDYECVAQNRFGLVVSRKARIQAATMSDFHVH----PQATVGEEGGVARFQCQIHGLPKPLITWEKNRVPIDTDNERYTLLPKGVLQITGLRAEDGGIFHCVASNIAS---IRISHGARLTVSGSGSGAYKEPAILVG---PENLTLTVHQTAVLECVATGNPRPIVSWSRLDGRPIGVEGIQVLGTGNLIISDVTVQHSGVYVCAANRPGTRVRRTAQGRLVVQAPAEFVQHPQSISRPAGTTAMFTCQAQGEPPPHVTWLKNGQVLGPGGHVRLKNNNSTLTISGIGPEDEAIYQCVAENSAGSSQASARLTVLWAEGLPG---------------------PPRNVRAVSVSSTEVRVSWSEPLANTKEIIGYVLHIRKAADPPELEYQEAVS-----------KSTFQHLVSDLEPSTAYSFYIKAYTPRGASSASVP------TLASTLGEAPAPPPLSVRVLGSSSLQLLWEPWPRLAQHEG-GFKLFYRP-ASKTSFTGPILLPGTVSSYNLSQLDPTAVYEVKLLAYNQH-GDGNATVRFVSLRGASERTALSPPCDCRKEEAANQTSTTGIVIG-IHIGVTCIIFCVLFLLFGQRGRVLLCKDVENQLSPPQGPRSQRD-PGILALNGARRGQRGQ-------------LGRDEKRVDMKELEQLFPPASAAGQPDPRPTQDPAAPAPCEETQLSVLPLQGCGLMEGKTTEAKTTEATAPCAGLAAAPPPPDGGPGLLSEGQASRPAAARVTQPAHSEQ-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VM64-1", "uniprot_id": "IHOG_DROME", "id": "Q9VM64-1", "name": "Interference hedgehog", "aln": "-MTLLTSSLLLFSLLTSRLEAIPVLEKSPAHPAHSAHPAHPAHPAHPAHPSPGVRILRAPESLVAPLGDEVVLECETSLQPERFEWSHRSSRSPGAGFKYLKTGTAKANVSQEAAISRLRVLVRPDTLGEYRCVGWFGPLVVTSTIARLELASTSLVDAQESESPLQWRVSAGNSVLWSCGQQVQSNPSASWSYYRNGVEIKPEFIGTN--GNLFLSNVSSESSGSYSCQATNPASGERIQLPGSLQLQVTPEQRSESKSPHLLRGQPSSQEITIREGSSLLLLCPGVGSPPPTVVWSSPDVVGAVKNKRSKVFGHALEISNTRVNDAGTYICFQDN-GVRPALEHYIKVHVEQPPQIVRPPWADLTNEGDRLKLECKATGVPTPEIYWLLNGHSSIDDSEAELSNN--FLILHSVLKRHAGYVQCFARNRLGEHSAGTLLQVNPKQIQEPRESGGTHRPKPNQGSRQKQMYPPTPPNVTRLSDESVMLRWMVPRNDGLPIVIFKVQYRMVGKRKNWQTTNDNIPYGKPKWNSELGKSFTASVTDLKPQHTYRFRILAVYSNNDNKESNTSAKFYLQPGAALDPMPVPELLEIEEYSETAVVLHWSLASDADEHLITGYYAYYRPSSSAGEYFKATIEGAHARSFKIAPLETATMYEFKLQSFSAASASEFSALKQGRTQRPKTSTTEEPTLQMGDRDTTTPSHNETFNMSPMLTGTIGGGAVLILLLISTCFCVCRRRNSRSRGNNPNKPRMAELRDDFVPLGNCSPTKQRQRTRHIHITLNPLAQQQQQALEEKNDTDQDAPYYQRPSSYDYDPTLRRMSSSSLRRSQRTLERAGGSNGSNN-----GNNNNLNQSAEAGSIENPGKPGRVLMKRPRLSSRSENLSSGSLNSVGV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::* . *:* . *: *. : : *.. :* *: ::* *... * : : *. *. : . * ** * **. *. *:*.**. ::.* **:: *: * ...: * . *. . :.* : .:* :*. * :: . * * * ::.: :*..* : * *:* ** :::. . :* *: . . *.* :* * .:::*: .: :* * ..*.* * * ** * : . : * **:. *:.:*.*:* :. *.* :: *: *.::*: * : * : *:* * *.*.: ** **: .....*.** * : .: .. . **.*.* *. .*.: * * : ** ... :*. .* : * * . *: : :: * ... : : : .:* * **:*. :* * * * ... . * . .::*. *.* *.:. ..::: * *. . :* *: :*** * .: . : . . *:::: *:.:::**.** ::. .. :::: : .. *: *. : ..:.:. : . : :. : *. :::**:. * :: ..: . *: ** . .::.*.. : * ::: : :: :* * ... . .* :.:. ..:* :: . . . ..: .* .. . . * :. : . ", "identical_positions": 149, "similar_positions": 275, "identity": "16.61%" }, { "cls_id": "homologset.agr.MGI:1202392", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F7EVW7-1", "uniprot_id": "F7EVW7_RAT", "id": "F7EVW7-1", "name": "GPI-anchor transamidase component GPAA1", "aln": "MGLLSDP--VRRRALARIVLRLNTPLCVLSYVAGIAWFLALAFPPLT---QRTYMSENAMGS--TMVEEQFVGGDRARNFARDFAAHRK-KPGALPVAWLERAMRSVGLEVYTQSFSRKLPFPDETHERYMVSGTNVYGILRAPRAASTESLVLTVPCGPDTTN----SQAVGLLLALAAHFRGQIYWAKDIIFLVTEHDLLGTEAWLEAYHDIN------VTGIQSSPLQGRAGAIQAAVALELSSDVVTSLDVTVEGLNGQLPNLDLLNLFQTFCQKGGLLCTLQGKLQPQDWTSLEGPLQGLQTLLLMVLRQASGRPHGPHG--LFLRYGVEALTLRGINSFRQYKYD------LVAVGKALEGMFRKLNHLLERLHQSFFFYLLPALSRFVSIGLYMPATGFLLLVLGLKISSTLLWMQLHEAGVNPEE-AGKAPGPGSPPLATQSVSLASLMAPLLISQAMGLALYFLPVLGQHVAAQHFPVAEAEAVVLTLLAIYVAGLALPHNTHRVVSSQVPDRGWMALKLVALIYLALQLGCIALLNFSLGFLLAATMVPAAALTKPHGPRTLYAALLVVTSPAVTLFGSLFLWRELQEVPLS----------LAEGWQLFLTALAQGVLEHYTYGALLFPILALGLYPCWLLFWNVLFWK---------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WTK3-1", "uniprot_id": "GPAA1_MOUSE", "id": "Q9WTK3-1", "name": "GPI-anchor transamidase component GPAA1", "aln": "MGLLSDP--VRRRALARIVLRLNTPLCVLSYVAGIAWFLALAFPPLT---QRTYMSENAMGS--TMVEEQFVGGDRARSFARDFAAHRK-KPGALPVAWLERSMRSVGLEVYTQSFSRKLPFPDETHERYMVSGTNVYGILRAPRSASTESLVLTVPCGPDATN----SQAVGLLLALAAHFRGQIYWAKDIIFLVTDHDLLGTEAWLEAYHDIN------VTGIQSSPLQGRAGAIQAAVALELSSDVVTSLDVTVEGLNGQLPNLDLLNLFQTFCQKGGLLCTLQGKLQPQDWTSLEGPLQGLQTLLLMVLRQASGRPHGPHG--LFLRYGVEALTLRGINSFRQYKYD------LATVGKALEGMFRKLNHLLERLHQSFFFYLLPALSRFVSIGLYMPATGFLLLVLGLKA--LELWMQLHQAGVNPEE-AGKAPSPGTPLLPTQGVGLASLTAPLLISQAMGLALYFLPVLGQHLATQHFPVAEAEAVVLTLLAIYVAGLALPHNTHRVVNSQVPDRGWMALKLVALIYLALQLGCIALLNFSLGFLLAATMVPAAALAKPHGPRTLYAALLVVTSPAVTLFGSLFLWRELLEVPLS----------LAEGWQLFLTALAQGVLEHYTYGALLFPILALGLYPCWLLFWNVLFWK---------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43292-1", "uniprot_id": "GPAA1_HUMAN", "id": "O43292-1", "name": "GPI-anchor transamidase component GPAA1", "aln": "MGLLSDP--VRRRALARLVLRLNAPLCVLSYVAGIAWFLALVFPPLT---QRTYMSENAMGS--TMVEEQFAGGDRARAFARDFAAHRK-KSGALPVAWLERTMRSVGLEVYTQSFSRKLPFPDETHERYMVSGTNVYGILRAPRAASTESLVLTVPCGSDSTN----SQAVGLLLALAAHFRGQIYWAKDIVFLVTEHDLLGTEAWLEAYHDVN------VTGMQSSPLQGRAGAIQAAVALELSSDVVTSLDVAVEGLNGQLPNLDLLNLFQTFCQKGGLLCTLQGKLQPEDWTSLDGPLQGLQTLLLMVLRQASGRPHGSHG--LFLRYRVEALTLRGINSFRQYKYD------LVAVGKALEGMFRKLNHLLERLHQSFFLYLLPGLSRFVSIGLYMPAVGFLLLVLGLKA--LELWMQLHEAGMGLEE-PGGAPGPSVPLPPSQGVGLASLVAPLLISQAMGLALYVLPVLGQHVATQHFPVAEAEAVVLTLLAIYAAGLALPHNTHRVVSTQAPDRGWMALKLVALIYLALQLGCIALTNFSLGFLLATTMVPTAALAKPHGPRTLYAALLVLTSPAATLLGSLFLWRELQEAPLS----------LAEGWQLFLAALAQGVLEHHTYGALLFPLLSLGLYPCWLLFWNVLFWK---------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BIU5-1", "uniprot_id": "A0A8M2BIU5_DANRE", "id": "A0A8M2BIU5-1", "name": "GPI-anchor transamidase component GPAA1", "aln": "MGLLSDP--NRRKALTNLLTRLNTPICVVCYLAAIVWFMGLAFEPFT---LRTYMSENAMGS--TMVEERFSAGERALAAAKEFNAHKR-KADGMPVEWLVKAMQARGLEVFTQSFFQKLPFPDENKERYMVRGTNVYGILRAPRAPRTEALVISAPCTPGGTN----NQAVGILLGLAQYFRNQVYWAKDIIFLVNEHDLIGMQAWLEGYHHTN------ITGMEYSPLQGRAGSIQAALSLELSSDVITSLDLVLEGLNGQLPNLDLANLFYAFCQKLNVLCTIQGKLQRNDWDSAEGYTHAAQTMMLMVLKQASGRSWGDHG--LFLRYHIEAASIRGINSFRHYKMD------ATTIGRLLEGMVRKLNNLLERLHQSYFFYLLPSLSRFVSIGYYMPAFGLLAVILLLRA--LDLWVHLGAPVLSEVDGVSEAEQPSSP-------GVLSVLTPVVISHLTGVALYILPVYLQDMAVEHFPVSETEAVVLTALAIYTAGLALPHNTQRLLSGEGTEQGWKVLKLTSLLYLAVLLGCTALINFSLGFILAVTLVPVTASITPHMLKSVSALAMVLLSPAFTIFYCVLIYQELMEAPVS----------LPEGLTIFLSVISQGILDHALYGSLVYPLLALFVYPCWLMFWNILFWK---------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W464-1", "uniprot_id": "Q9W464_DROME", "id": "Q9W464-1", "name": "", "aln": "MGLLSDPSISTQSKLVDGLARHVRKVCYALYVAGVAWFFCLALPEFN---HGTYLSENALSPGLVYPEIRIDANRLAIQLLEELQRERKDHLSTTPHAWIAAKMNEFGLETHTHNYTLRYPFGGGKE----YHGKNIYGILRAPRIASTEGIVFAAPYRAASSVHTDISASVPLLLAFADFARRKNYWAKDLIFLITEQEQLGMQAWLEAYHDGDRELDLSKAYLRPGNLPARAGSLQAALNIEVQDLEIDHVDVRIEGLNGKLPNLDMFNLVQRIMAREGIASGYKQAPRKKRRHSQSHFEQNFRQMLTMLASQSSGVPTGNHG--LFHRYRIDALTIAANRRATHATLKGSPGSAAVPLLKAIEGIARSLNNLLERFHQSFFFYVIVSNDRYISIGDYMPALVALVACAFLKAYLTWSTLPATNAELEKAAGWLREHEQEAELEENLEPDKFELPYGSVLIYLTATLLIGFLCNVLPLQQYFLEIPMGAAPLTTSVLSFLSLIGFVLPFVVVLPP----GGLELLHVAFLLIYGCALIVIGLLNFALGLFAAVLTVPLVIALETKEENSRSTLRNTIRLATLVMNPMMVVYVIVLAMTFYQFPELPVQKIMLRAATAAMDASAYGLIDSVIYGNWLYFVICTIFLPLWIICWTLSLSKRRDYADYLDFDESPSTSPQPQSKVKTN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39012-1", "uniprot_id": "GAA1_YEAST", "id": "P39012-1", "name": "GPI transamidase component GAA1", "aln": "MALLEKL--HRRIVDMGLVPRIIALLPVISMLCALFGFISIAILPMDGQYRRTYISENALMP----------SQAYSYFRESEWNILRGYRSQIKEMVNMTSMERNNLMGSWLQEFGTKTAIYENEQ-----YGETLYGVMHAPRGDGTEAMVLAVPWFNSDDEFN--IGGAALGVSLARFFSRWPVWSKNIIVVFSENPRAALRSWVEAYHTSL-------------DLTGGSIEAAVVLDYSSTEDFFEYVEISYDGLNGELPNLDLVNIAISITEHEGMKVSLHGLP--SDQLTNNNFWSRLKILCLGIRDWALSGVKKPHGNEAFSGWRIQSVTLKAHGNSGHDITT---------FGRIPEAMFRSINNLLEKFHQSFFFYLLLAPRQFVSISSYLPSAVALSIAFAISS--LNAFINNAYANISLFSEYNLVA---------LLVWFVSLVISFVVSQAFLLIPSSGLLMTISMASCFLPLILSRKIHISEPLSYR-LKNVAFLYFSLVSTSLLMINFAMALLIGTLAFPMTFVKTIVESSSEHEVTTQSSNPIKTEPKDEIELVENHMDTTPATPQQQKQKLKNLVLLILTNPFISITLFG---LFFDDEFHGFDIINKLVSAWLDLKCWSWFVLCIGWLPCWLLILASSFESKSVVVRSKEKQS---------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.**.. : : * : :..: *: :.: : **:****: . . : : : : : . : :.: : .: . * .:**:::*** **.:*::.* .. : :.:* . *:*:::.:..:: . .:*:*.** * . : ..: . . . ::: :****:*****: *: : : .: : . : . : : : : . ** * : ::: :: . : . : *.: *.:*:***::***:*:*:: . :::**. *:*: * : : . : .: :: : .: : : : . :: . : : : : . : . : * . . . : : .. : : : : ::. * *:: : . ", "identical_positions": 61, "similar_positions": 165, "identity": "8.88%" }, { "cls_id": "homologset.agr.MGI:1202394", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P17267-1", "uniprot_id": "IF_RAT", "id": "P17267-1", "name": "Cobalamin binding intrinsic factor", "aln": "MAWLS----FYLLNVLWAVAGTSTRAQRSCSVPPDQQP--------------WVNGLQLLMENSVTESDLPNPSILIAMNLAS---------TYNLEAQKLLTYQLMASDSADLTNGQLALTIMALTSSCRDP------------------------------------------------------GSKVSILQKNMESWTPSNLGAE-----------SSSFYGPALAILALCQKNSEATLPIAVRFAKTLMMESSPFSVDTG----------------------AVATLALTCMYNRIPVGSQENYRDLFGQALKVIVDNISLRIKAD------------------------------GIIGDIYSTGLAMQALSVTPEQPTKEWDCEKTMYTILK--EIKQGKFQNPMS-----------IAQILPSLKGKTYLDVPQVTCGPDHEVPPTLTDYPTP---------VPTSISNITVIYTINNQLRGVDLLFNVTIEVSVKSGSVLLAVLEEAQRRNHMFKFETTMTSWGLIVSSINNIAENVKHKTYWEFLSG-------KTPLG-----EGVAYYIPFNYEHITANFTQY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P52787-1", "uniprot_id": "IF_MOUSE", "id": "P52787-1", "name": "Cobalamin binding intrinsic factor", "aln": "MAWLT----LYLLSVLWAVAGTSTRAQSSCSVPPDQQP--------------WVDGLQALMENSVTDSDFPNPSILIAMNLAG---------AYNVEAQKLLTYQLMASDSADLTSGQLALTVMALTSSCRDP------------------------------------------------------GSKVSTLLKKMENWSPSSPGAE-----------SSAFYGPGLAILALCQKSSEATLPIAVRFAKTLMMEPSPFNVDTG----------------------AVATLALTCMYNKIPVGSQENYRDLFGQALKAIVEKISLRIKAD------------------------------GIIGDIYSTGLAMQALSVTPEQPTKKWDCEKTMHTILN--EIKQGKFQNPMS-----------IAQILPSLKGKTYLDVPQVTCGPDHEVPPTLTDYPTP---------VPTSVSNITVIYTINNQLRGVDLLFNVTIEVSVKSGSVLLAVLEEAQRKNSMFKFETTMTSWGLIVSSINNIAENVNHKTYWEFLSG-------KTPLD-----EGVAYYIPFNHEHITANFTQY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P27352-1", "uniprot_id": "IF_HUMAN", "id": "P27352-1", "name": "Cobalamin binding intrinsic factor", "aln": "MAWFA----LYLLSLLWATAGTSTQTQSSCSVPSAQEP--------------LVNGIQVLMENSVTSSAYPNPSILIAMNLAG---------AYNLKAQKLLTYQLMSSDNNDLTIGQLGLTIMALTSSCRDP------------------------------------------------------GDKVSILQRQMENWAPSSPNAE-----------ASAFYGPSLAILALCQKNSEATLPIAVRFAKTLLANSSPFNVDTG----------------------AMATLALTCMYNKIPVGSEEGYRSLFGQVLKDIVEKISMKIKDN------------------------------GIIGDIYSTGLAMQALSVTPEPSKKEWNCKKTTDMILN--EIKQGKFHNPMS-----------IAQILPSLKGKTYLDVPQVTCSPDHEVQPTLPSNPGP---------GPTSASNITVIYTINNQLRGVELLFNETINVSVKSGSVLLVVLEEAQRKNPMFKFETTMTSWGLVVSSINNIAENVNHKTYWQFLSG-------VTPLN-----EGVADYIPFNHEHITANFTQY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W4K2-1", "uniprot_id": "Y3556_DROME", "id": "Q9W4K2-1", "name": "Uncharacterized protein CG3556", "aln": "MLSLSSPPWLLLLVLFFFANGSATVVSLAENVTLATLPSTSPISVSFSTTSSVVAPISTELENQTASSSNLNTNNEASDEQTGNSNSNTSSHSRNINGLPSSNSNIDNANSNSSSVSSLSTTTSAISGVDQQESLILATPTALNGSGTPPEHQTIGQAPPTKGEQEAILRALDWLKEKRASDYGWGNDTHVVILAKELSGGRDPNDSVDGHVQVIQELEDTLSVKEMEIEILAMLDRHHTLPKPLDLDKLARYVLALGSLCKDPKHFHGHDLVATLQHHEPAQDIEFALTTLSACSSAAHVRKRQIRRLLDIASGVTDQSVDAIAMVILALRCIVTDHRHRHLQHFVRRPARGLATLQDQRGSFGSLRSTALAMQALQDLEYDPAGHWNRTAASRYILSRQRADGGWSEEPLQDGQEPDIGVGLTADIILALGWKGLGAVRALQCDHVIRESSDPTENGEPKLAVPFGLSSSAEESDAKNISYTYTLWVGSNVTESFSLSLVSPKNTSFFKAMTQAAEMDPRFIFEAREWPNGHYVHTLYGKKEEPRGYHYWLLYRLPELPDPNNTPGNQLIAPVGVDELMVEDGEHYLYWYKKL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :: : ** ::: . *::* .. : .*. * * :. :**..:.* *.. : : :. : *::. . :: ::. . : ..*. * *::. :: . :* * :::.. .. ..: : :. : ***: :: . *: : : ..: *. *::**: . :: . . .: . . . *: *:: * * :*.: **.******. . .*: : **. . . * .:*:. *:*: :* * * : *. . . .. * .:. *: . * . * :: . ::.: ..: :: .: :* . : * **: . * * :: . *: . ** : ** . ** : : ** :.: ", "identical_positions": 69, "similar_positions": 152, "identity": "11.6%" }, { "cls_id": "homologset.agr.MGI:1202395", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O70138-1", "uniprot_id": "MMP8_MOUSE", "id": "O70138-1", "name": "Neutrophil collagenase", "aln": "MFRLKTLPLLIFLHTQ--------------LANAFPVP-EHLEEKNIKTAENYLRKFYNLPSNQFRSSRN--ATMVAEKLKEMQRFFSLAETGKLDAATMGIMEMPRCGVPD--------SGDFLLTPGS-----------PKWTHTNLTYRIINHTPQLSRAEVKTAIEKAFHVWSVASPLTFTEILQGEADINIAFVSRDHGDNSPFDGPNGILAHAFQPGQGIGGDAHFDSEETWTQD-----SKNYNLFLVAAHEFGHSLGLSHSTDPGALMYPNYAYREPSTYSLPQDDINGIQTIYGPSDN-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------PIQPTGPSTPKACDP-----------------------HLRFDATTTLRGEIYFFKDKYFWRR-HPQLRTVDLNFISLFWPFLPN---GLQAAYEDFDRDLVFLFKGRQYWALSGYDLQQGYPRDISNYGFPRSVQAIDAAVSY--NGKTYFFINNQCWRYDNQRRSMDPGYPKSIPSMFPGVNCRVDAVFL-QDSFFLFFSGPQYFAFN---FVSHRVTRVARSNLWLNCS--------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O88766-1", "uniprot_id": "MMP8_RAT", "id": "O88766-1", "name": "Neutrophil collagenase", "aln": "MLHLKTLPFLFFFHTQ--------------LATALPVPPEHLEEKNMKTAENYLRKFYHLPSNQFRSARN--ATMIAEKLKEMQRFFGLPETGKPDAATIEIMEKPRCGVPD--------SGDFLLTPGS-----------PKWTHTNLTYRIINHTPQMSKAEVKTEIEKAFKIWSVPSTLTFTETLEGEADINIAFVSRDHGDNSPFDGPNGILAHAFQPGRGIGGDAHFDSEETWTQD-----SKNYNLFLVAAHEFGHSLGLSHSTDPGALMYPNYAYREPSTYSLPQDDINGIQTIYGPSDN-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------PVQPTGPSTPTACDP-----------------------HLRFDAATTLRGEIYFFKDKYFWRR-HPQLRTVDLNFISLFWPFLPN---GLQAAYEDFDRDLVFLFKGRQYWALSAYDLQQGYPRDISNYGFPRSVQAIDAAVSY--NGKTYFFVNNQCWRYDNQRRSMDPGYPTSIASVFPGINCRIDAVFQ-QDSFFLFFSGPQYFAFN---LVSRRVTRVARSNLWLNCP--------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P22894-1", "uniprot_id": "MMP8_HUMAN", "id": "P22894-1", "name": "Neutrophil collagenase", "aln": "MFSLKTLPFLLLLHVQ--------------ISKAFPVS---SKEKNTKTVQDYLEKFYQLPSNQYQSTRKNGTNVIVEKLKEMQRFFGLNVTGKPNEETLDMMKKPRCGVPD--------SGGFMLTPGN-----------PKWERTNLTYRIRNYTPQLSEAEVERAIKDAFELWSVASPLIFTRISQGEADINIAFYQRDHGDNSPFDGPNGILAHAFQPGQGIGGDAHFDAEETWTNT-----SANYNLFLVAAHEFGHSLGLAHSSDPGALMYPNYAFRETSNYSLPQDDIDGIQAIYGLSSN-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------PIQPTGPSTPKPCDP-----------------------SLTFDAITTLRGEILFFKDRYFWRR-HPQLQRVEMNFISLFWPSLPT---GIQAAYEDFDRDLIFLFKGNQYWALSGYDILQGYPKDISNYGFPSSVQAIDAAVFY--RSKTYFFVNDQFWRYDNQRQFMEPGYPKSISGAFPGIESKVDAVFQ-QEHFFHVFSGPRYYAFD---LIAQRVTRVARGNKWLNCRYG------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8MPP3-1", "uniprot_id": "D2MP_DROME", "id": "Q8MPP3-1", "name": "Matrix metalloproteinase-2", "aln": "MFSKYVLATLLALFAQSMCIQELSLPPEGSHSTAATRSKKAKTAISEDIMYNYLMQFDYLPKSDLETGALRTEDQLKEAIRSLQSFGNITVTGEIDSATARLIQKPRCGVGDRRSADSFSPDNLYHEIGSNVRVRRFALQGPKWSRTDLTWSMVNRS-MPDASKVERMVQTALDVWANHSKLTFREVYSDQADIQILFARRAHGDGYKFDGPGQVLAHAFYPGEGRGGDAHFDADETWNFDGESDDSHGTNFLNVALHELGHSLGLAHSAIPDAVMFPWYQNNEVAGN-LPDDDRYGIQQLYGTKEKTWGPYKPQTTTTTTTTTTMRAMIYRADKPAYWPWNNPSNNPNNDRNRARERQEEERRRQEKERRRQEEERRHQEEERRRQVEERQRQEEERWRQEQERQEEENRRRKIEHKSQWERNPSKERNRPRERQEMERRRQEQERQEQERQEQEDRRRERERDRQLEWERRNRNGAREPVTPTANTTPRPTNKPYPTVHRQHHHHNKPRKPKPDSCMTYYDAISIIRGELFIFRGPYLWRIGTSGLYNGYPTEIRRHWSALPENLTKVDAVYENKQRQIVFFIG-REYYVFNSVMLAPGFPKPLASLGLPPTLTHIDASFVWGHNNRTYMTSGTLYWRIDDYTGQVELDYPRDMS-IWSGVGYNIDAAFQYLDGKTYFFKNLGYWEFNDDRMKVAHARAKLSARRWMQCARSANEVDDEQRWTASLVSEGEETGRSGSRELRINHFILSILLLAIANWRS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: .*. *: :..* :.* . . . . :** :* **..: .: : * ::.:* * .: **: : * ::: ***** * ...: *. *** :*:**: : * : . ::*: :: *:.:*: * * * . ..:***:* * * ***. ****. :***** **.* *******::***. * . *:: ** **:******:**: *.*:*:* * .* : **:** *** :** ..: *: **. :** . : :** : :***: :*:. *:** . * . * .*. ** ::*.**: :*:::*:: .:*:.:.. : *:*: ::. *:* :: ***:. : ..:**: . ** *: :: .** .:. :.*: .:**.* : .*.. *: *: : :. .. *::* ", "identical_positions": 144, "similar_positions": 157, "identity": "18.9%" }, { "cls_id": "homologset.agr.MGI:1202397", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AP01-1", "uniprot_id": "A0A8I6AP01_RAT", "id": "A0A8I6AP01-1", "name": "", "aln": "MPILLFLIDTSASMNQRSHLG---TTYLDTAKGAVETFMKLRARDPASRGDRYMLVTFEEPPYAIKAGWKENHATFMNELKNLQAEGLTTLGQSLRTAFDLLNLNRLVTGIDNYGQGRNPFFLEPAIIITITDGSKLTTTSGVQDELHLPLNSPLPGSELTKEPFRWDQRLFALVLRLPGTVSVESEQLTGVPLDDSAITPMCEVTGGRSYSVCSPRMLNQCLESLVQKVQSGVVINFEKAGPDPSPA-EDGQPDISRP-----------FGSQP---WHSCHKLIYVRPNP-KTGVPIGHWPVPESFWPDQNSPTLPPRTSHPVVKFSCTDC-EPMVIDKLPFDKYELEPSPLTQFILERKSPQTCWQVYVSNSAKYNELGHPFGYLKASTALTCVNLFVMPYNYPVLLPLLDDLFKVHKAKPTLKWRQSFESYLKTMPPYYLGPLKKAVRMMGAPN-----LIADSMEYGLSYSVISYLKKLSQQAKIESDRVIGSVGKKVVQETGIKVRSRSHGLSMAHRKGFQ-VLQGISEDVPHRLL-DLNMKEYTGFQVALLNKDLKPQTFRNAYDIPRRNLLDHLTRMRSNLLKSTRKFLKGQDEDQVHSVPIAQMGNYQEYLKQVPSPLRELDPDQPRRLHTFGNPFKLDKKGMMIDEADEFVAGPQNKHK-------RPGEPSMQGIPK----------------------------------------------------RRRCASPLLR----------GRRQSPAVNSHIGGKGPPAPM----------------------------------------------------------------------------------------------TQAQPG--------------------LIKPLPLHK--EATNDSVVDDVVENHVADQLSSDMTT--------NAMDTEFLTS-----PANLLEPSTN------------------------------HTEALG--------------------------------HEHLGNNDLTVGGFLENHEESRSKEQSAEENIPASSLNK-----------------------------------------------------------------------------------------------------------GKKLMHCRSHEEV------NTELKAQIMKEIRKPGRKYERIFTLLKHVQGSLQTRLIFLQNVIKEASRFKKRMLIEQLENFLDEIHRR---ANQINHINSN------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PCM2-1", "uniprot_id": "INT6_MOUSE", "id": "Q6PCM2-1", "name": "Integrator complex subunit 6", "aln": "MPILLFLIDTSASMNQRSHLG---TTYLDTAKGAVETFMKLRARDPASRGDRYMLVTFEEPPYAIKAGWKENHATFMNELKNLQAEGLTTLGQSLRTAFDLLNLNRLVTGIDNYGQGRNPFFLEPAIIITITDGSKLTTTSGVQDELHLPLNSPLPGSELTKEPFRWDQRLFALVLRLPGTMSVESEQLTGVPLDDSAITPMCEVTGGRSYSVCSPRMLNQCLESLVQKVQSGVVINFEKAGPDPPPA-EEGQPDISRP-----------FGSQP---WHSCHKLIYVRPNP-KTGVPIGHWPVPESFWPDQNSPTLPPRTSHPVVKFSCTDC-EPMVIDKLPFDKYELEPSPLTQFILERKSPQTCWQVYVSNSAKYNELGHPFGYLKASTALTCVNLFVMPYNYPVLLPLLDDLFKVHKAKPTLKWRQSFESYLKTMPPYYLGPLKKAVRMMGAPN-----LIADSMEYGLSYSVISYLKKLSQQAKIESDRVIGSVGKKVVQETGIKVRSRSHGLSMAHRKGFQ-VLQGISEDVPHRLL-DLNMKEYTGFQVALLNKDLKPQTFRNAYDIPRRNLLDHLTRMRSNLLKSTRKFLKGQDEDQVHSVPIAQMGNYQEYLKQVPSPLRELDPDQPRRLHTFGNPFKLDKKGMMIDEADEFVAGPQNKHK-------RPGEPSMQGIPK----------------------------------------------------RRRCASPLLR----------GRRQSPAVNSHIGGKGPPAPM----------------------------------------------------------------------------------------------TQAQPG--------------------LIKPLPLHK--EATNDSIVDDVVENHVADQLSSDMTP--------NAMDTEFLTS-----PPNLLEPSTN------------------------------HTEALG--------------------------------HEHLGNNDLTVGGFLENHEEPRNKEQSAEENIPASSLNK-----------------------------------------------------------------------------------------------------------GKKLMHCRSHEEV------NTELKAQIMKEIRKPGRKYERIFTLLKHVQGSLQTRLIFLQNVIKEASRFKKRMLIEQLENFLDEIHRR---ANQINHINSN------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UL03-1", "uniprot_id": "INT6_HUMAN", "id": "Q9UL03-1", "name": "Integrator complex subunit 6", "aln": "MPILLFLIDTSASMNQRSHLG---TTYLDTAKGAVETFMKLRARDPASRGDRYMLVTFEEPPYAIKAGWKENHATFMNELKNLQAEGLTTLGQSLRTAFDLLNLNRLVTGIDNYGQGRNPFFLEPAIIITITDGSKLTTTSGVQDELHLPLNSPLPGSELTKEPFRWDQRLFALVLRLPGTMSVESEQLTGVPLDDSAITPMCEVTGGRSYSVCSPRMLNQCLESLVQKVQSGVVINFEKAGPDPSPV-EDGQPDISRP-----------FGSQP---WHSCHKLIYVRPNP-KTGVPIGHWPVPESFWPDQNSPTLPPRTSHPVVKFSCTDC-EPMVIDKLPFDKYELEPSPLTQFILERKSPQTCWQVYVSNSAKYSELGHPFGYLKASTALNCVNLFVMPYNYPVLLPLLDDLFKVHKAKPTLKWRQSFESYLKTMPPYYLGPLKKAVRMMGAPN-----LIADSMEYGLSYSVISYLKKLSQQAKIESDRVIGSVGKKVVQETGIKVRSRSHGLSMAYRKDFQQLLQGISEDVPHRLL-DLNMKEYTGFQVALLNKDLKPQTFRNAYDIPRRNLLDHLTRMRSNLLKSTRRFLKGQDEDQVHSVPIAQMGNYQEYLKQVPSPLRELDPDQPRRLHTFGNPFKLDKKGMMIDEADEFVAGPQNKHK-------RPGEPNMQGIPK----------------------------------------------------RRRCMSPLLR----------GRQQNPVVNNHIGGKGPPAPT----------------------------------------------------------------------------------------------TQAQPD--------------------LIKPLPLHKISETTNDSIIHDVVENHVADQLSSDITP--------NAMDTEFSASS----PASLLERPTN------------------------------HMEALG--------------------------------HDHLGTNDLTVGGFLENHEEPRDKEQCAEENIPASSLNK-----------------------------------------------------------------------------------------------------------GKKLMHCRSHEEV------NTELKAQIMKEIRKPGRKYERIFTLLKHVQGSLQTRLIFLQNVIKEASRFKKRMLIEQLENFLDEIHRR---ANQINHINSN------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7SYD9-1", "uniprot_id": "INT6_DANRE", "id": "Q7SYD9-1", "name": "Integrator complex subunit 6", "aln": "MPILLFLIDTSASMNQRTYLG---TTYLDIAKGAVEIFMKLRARDPASRGDRYMLVTFDDPPYGVKAGWKENHATFMSELKNLQASGLTTLGHALRAAFDLLNLNRLVSGIDNYGQGRNPFFLEPSVIITITDGNKLTHSSGVAEELHLPLNSPLPGSELTKEPFRWDQRLFALVLRLPGVAVPDSEQLGSVPTDESAITQMCEVTGGRSYCVRTQRMLNQCLESLVQKVLSGVVIHFEKTGPDPPVIGEDGLVDPARPLT--------SFSPQP---WHSCHKLIYVRPNP-KTGVPVGHWPISESFWPDQNSPTLPPRSAHPVVRFSCVDC-EPMVIDKLPFDKYELEPSPLTQYILERKSPHMCWQVFVNCSGKHSDVAHPFGYLKASTTLTCVNLFVMPYNYPVLLPLLDDLFKVHKLKPNLKWRQSFEMYLKSMPPYYLLPLKKALRMMGAPN-----LISDNMDCGLSYSVISYLKKLSQQAKIESDRLIVSVGKKPPPETGIKVKNHSNALSLAHRRDFKQLLQGITGEVPLRLI-DMNFKEFAGFQIALLNKDLKPQAYRNAYDIPRRNLLDQVTRMRSNLLRTTQKLIRGQDDDSLHSIPVGQMGNYQEYLKMMPSPLREIDPDQPKRLHTFGNPFKQDKKGMMIDEADEFVTGPQNKKRG------NTGDLNSGTALK----------------------------------------------------RRRSMSPLLR----------RPQTPPIITNHVLGKGPTG------------------------------------------------------------------------------------------------TQGQQG--------------------IIKPIPLHKGAEGNNVGGTESNGE-RVAGTDAGDCWP--------GEVDGESGEPA----PVEDREDAAAP---------------------------DGEEEILA--------------------------------LENCLDD--RSPDHTQNCEELSPPGQEGEMEVNEGDTP------------------------------------------------------------------------------------------------------------AQGTIVMIPLEGS------NAELRTRVIKEVRKPGRNYEAIFRLLEEVKGPVSVQRYFIHHAIKEAARFKKRMLIQQLETALEEIEDRQMLPAQINNIHSR------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W485-1", "uniprot_id": "INT6_DROME", "id": "Q9W485-1", "name": "Integrator complex subunit 6", "aln": "MTIILFLVDTSSSMCQKAYVNGVQKTYLDIAKGAVETFLKYRQRTQDCLGDRYMLLTFEEPPANVKAGWKENHATFMNELKNLQSHGLTSMGESLRNAFDLLNLNRMQSGIDTYGQGRCPFYLEPSVIIVITDGGRYSYRNGVHQEIILPLSNQIPGTKFTKEPFRWDQRLFSLVLRMPGNK-IDERVDGKVPHDDSPIERMCEVTGGRSYRVRSHYVLNQCIESLVQKVQPGVVLQFEPMLPKEATSATAGEAAGASTISGMGISSTSGAGPAPDIVFQPVKKMIYVQKHITQKTFPIGYWPLPEPYWPDSKAITLPPRDAHPKLKVLTPAVDEPQLVRSFPVDKYEIEGCPLTLQILNKREMNKCWQVIVTNGMHGFEL--PFGYLKAAPNFSQVHLYVLAYNYPALLPILHDLIHKYNMSPPSDLMYKFNAYVRSIPPYYCPFLRKALVNINVPYQLLQFLLPENVDNYLSPTIANQLKHIKNTAKQDQENLCMKVYKQLKQPKPPYRQVETGKLFTGAPLRRDLVRHPLLRDIFSKLHGEIDPVENYTIVVPQPTHQSSAKSHRNPFDIPRRDLVEEIAKMRETLLRPVSLVAK----DSGHCLPIAEMGNYQEYLKNKDNPLREIEPTN-VRQHMFGNPYKKDKHMVMVDEADLSDVAPMKSPNGNGPGGAPPGSPSGSGSPTGPGPSSPGSSPGGGSGPGMPGMPGMGGGMSGLMLGAGGSGGSSKKLDGTSRGRKRKAGPLPRSFEFRRSSTDSRSSSSGSESSTTGSAPGSPIPGATSSISGCDSAMGADGGPSSSCFDEDSNSNSSFVSSTSEASASDSGMSNSHLDPLRISFVFIEEETSDQDTPLNGYVHNFINGISDDAETGETEAVPGGASLPGASSANEPSSIGASPAVSATPATSVIPASNGSEVCSAVAAGSSSSISSSASSPGVLYVPLNGLTTHAAYSSNLGGPSSPLDNLSSLGGAAGGGGSGLLGVSKPGSLPLANGYGHGHSSAISPPSPLSLVPLSPLGTSTPAASSSGLSSSSAYFSHNDINDASEISRILQTCHNGTSSGSSVGAGASNSNLNGNGSTESGGGVSSDDHASLGGNSFDALKRTAGTAGSTAAGNPHYYWASGLNHHNNNNSSAAGAASGSTLSNNHNHRGHNNSSPNKLEVKINSSCGSSPTHNNGGMGSPGQSLPLIFTEEQREAARLHNVELRLQIFRDIRRPGRDYSQLLEHLNLVKGDQDMQSDFVDMCIVESLRFRRHRMASSIQEWWDRKQQLTAVGTNEATPSAEQAVAKS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.*:***:***:** *::::. .**** ****** *:* * * . ******:**::** :************.******: ***::*.:** *********: :***.***** **:***::**.****.: : .** :*: ***.. :**:::************:****:** :.. ** *:*.* ********** * : :****:******* .***::** *. . * : . .. * ::. :*:***: : :. .*:*:**:.*.:***.:: ***** :** ::. ** :: .:*.****:* .*** **:::. : **** *. . : :: *******:. :. *:*:*:.****.***:*.**:: :: .* . .*: *::::**** *:**: :..* *:.:.:: ** :: . **::.: ** :.:.: .* *: . : .: * . . : : : :: :* ::: * : :. .:: ..::.**.:*****:*::.:::**..**:.. . : *. *.:*:.:********* .****::* : * * ****:* **: :*:**** ..* :. . .*. . . *:* .** * . . *..* . *:. . :.. * . .* . . :. :.. . . : . . * . : : . . :. .: : :. .: . .. .: . * *.**: ::::::*:***.*. :: *: *:* . : *:. * *: **::: : ..:: :. . : :. ", "identical_positions": 301, "similar_positions": 294, "identity": "23.3%" }, { "cls_id": "homologset.agr.MGI:1202398", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZVD7-1", "uniprot_id": "D3ZVD7_RAT", "id": "D3ZVD7-1", "name": "Keratocan", "aln": "MATPTCLILWVLLIVDTVWTQSVRQAYEVQDPEEWDVHDDFYCPRECFCPPSFPTALYCENRGLTEIPAIPSRIRYLYLENNLIETIPEKPFENATQLRWINLNKNKITNYGIEKGALSQLKKLLFLFLEDNELEEVPSPLPRSLEQLQLARNKVSSIPQGTFSNLENLTLLDLQHNKLLDNAFQRDTFKGLKNLMQLNMAKNALRNMPPRLPANTMQLFLDNNSIEGIPENYFNVIPKVAFLRLNHNKLSDAGLPSRGFDVSSILDLQLSHNQLTNFPRINANLQHLHLDHNKIKNVNMSVICP--STLRAGQDAFLHGPQLSYLRLDGNEIKPPIPMDLVACFKLLQAFII", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35367-1", "uniprot_id": "KERA_MOUSE", "id": "O35367-1", "name": "Keratocan", "aln": "MATPNCLILWVLLIADTVWTQSVRQAYEIQDPEDWDVHDDFYCPRECFCPPSFPTALYCENRGLTEIPPIPSRIWYLYLENNLIESIPEKPFENATQLRWINLNKNKITNYGIEKGALSQLKKLLFLFLEDNELEEVPSPLPRSLEQLQLARNKVSRIPQGTFSNLENLTLLDLQHNKLLDNAFQRDTFKGLKNLMQLNMAKNALRNMPPRLPANTMQLFLDNNSIEGIPENYFNVIPKVAFLRLNHNKLSDAGLPSRGFDVSSILDLQLSYNQLTNFPRINANLQHLHLDHNKIKNVNMSVICP--TTLRAEQDAFIHGPQLSYLRLDGNEIKPPIPIDLVACFKLLQAFII", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60938-1", "uniprot_id": "KERA_HUMAN", "id": "O60938-1", "name": "Keratocan", "aln": "MAGTICFIMWVLFITDTVWSRSVRQVYEVHDSDDWTIHD-FECPMECFCPPSFPTALYCENRGLKEIPAIPSRIWYLYLQNNLIETIPEKPFENATQLRWINLNKNKITNYGIEKGALSQLKKLLFLFLEDNELEEVPSPLPRSLEQLQLARNKVSRIPQGTFSNLENLTLLDLQNNKLVDNAFQRDTFKGLKNLMQLNMAKNALRNMPPRLPANTMQLFLDNNSIEGIPENYFNVIPKVAFLRLNHNKLSDEGLPSRGFDVSSILDLQLSHNQLTKVPRISAHLQHLHLDHNKIKSVNVSVICPSPSMLPAERDSFSYGPHLRYLRLDGNEIKPPIPMALMTCFRLLQAVII", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5RI43-1", "uniprot_id": "KERA_DANRE", "id": "Q5RI43-1", "name": "Keratocan", "aln": "-MSRLNLTMEVLLVAFVAVFLTS-QVHSDEIPYEHLMSQLQACPKECNCPPNFPNAVYCDNKGLKSIPVIPPYTWYLYLQNNLIDVLSANALRNATQLKWINLNRNKITTEGLEVDALRAMSNLVHLYMEDNLLSSIPSPLPAKLEQLRLSRNKISKIPPGVFSGMGHLTLLDLQSNKLQDDAVTEVSLKGLNNLIQINLAKNQLNSMPLGLPPTTTQIFLDGNNIEKIPAEYFKGLPKVASLRLNRNKLANGGIPKNVFNLSSILDLQLSHNQLTEVPVISSGLEHLHLDHNKIKSVNSSDICP-PGVLDDHLE--EKSPRLRYLRLDGNEIQPPIPRELMTCFRLLRAVVI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : **::. .. : *.:. . . : : : ** ** ***.**.*:**:*:**..** **. ****:****: :. :.:.*****:*****:****. *:* .** :.:*:.*::*** *..:***** .****:*:***:* ** *.**.: :******* *** *:*. . ::***:**:*:*:*** *..** **..* *:***.*.** ** :**: :**** ****:***:: *:*.. *::*********:****:.* *.: *:**********.** * *** * : .*:* *********:**** *::**:**:*.:*", "identical_positions": 181, "similar_positions": 99, "identity": "51.27%" }, { "cls_id": "homologset.agr.MGI:1202400", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZR84-1", "uniprot_id": "A0A8I5ZR84_RAT", "id": "A0A8I5ZR84-1", "name": "Transcription elongation factor SPT5", "aln": "---------------------------------------------------------------MSDSEDSNFSEEEDSERSSEAEEAEVEED---RRSAAGS------------------------------------EKEEEPE-EEEEEEEEEYDEEEEEEDDDRPPKKPR---HGGFILDEADVDDEYEDEDQWEDG---AEDILEKALFPASNIDNVVLDEDRSGARRLQNLWRDQREE---ELGEYYMKKYAKSSVGETVYG-GSDELSDDITQQQLLPGVKDPNLWTVKCKIGEERATAISLMRKFIAYQFTDTP--LQIKSVVAPEHVKGYIYVEAYKQTHVKQAIEGVGNLRLGYWNQQMVPIKEMTDVLKVVK-EVANLKPKSWVRLKRGIYKDDIAQVDYVEPSQNTISLKMIPRIDYDRIKARMS---LKDWFAKRKKFKRPPQRLFDAEKIRSLGGDVASDGDFLIFEGNRYSRKGFLFKSFAMSAVITEGVKPTLSELEKFEDQPEGIDLEVV--TESTGKEREHNFQPGDNVEVCEGELINLQGKVLSVDGNKITIMPKHEDLKDMLEFPAQELRKYFKMGDHVKVIAGRFEGDTGLIVRVEENFVILFSDLTMHELKVLPRDLQLCSETASGVDVGGQHEWGELVQLDPRTVGVIVRLERETFQVLNMHGKVVTVRHQAVTQKKDNRFAVALDSDQNNIHVKDIVKVIDGPHSGREGEIRHLYRSFAFLHCKKLVENGGMFVCKARHLVLAGGSKPRDVTNLTVGGFTPMSPRISSPMHPSAEGEMGSEFRDWSWEEPYLFNLRALGQSGVWKGLGFTEQVEELLTQLGGLTLVERDLRMSWLWAQHKRDKHNSWAPTSSHPTGQHGGFGSPGG----MSRGRGRRDNELIGQTVRISQGPYKGYIGVVKDATESTARVELHSTCQTISVDRQRLTTVDSQRPGGMTSTYG----RTPMYGSQTPMY-GSGSRTPMYGSQTPLQDGSRTPHYGSQTPLHDGSRTPAQSGAWDPNNPNTPSRAEEEYEYAFDDEPTPSPQAYGGTPNPQTPGYPDPSSPQVNPQYNPQTPGTPAMYNTDQFSPYAAPSPQGSYQPSPSPQSYHQVAPSPAGYQNTHSPASYHPTPSPMAYQASPSPSPVGYSPMTPGAPSPGGYNPHTPGSGIEQNSSDWVTTDIQVKVRDTYLDTQIVGQTGVIRSVTGGMCSVYLKDSEKVVSISSEHLEPITPTKNNKVKVILGEDREATGVLLSIDGEDGIIRMDLEDQQIKILNLRFLGKLLEA-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O55201-1", "uniprot_id": "SPT5H_MOUSE", "id": "O55201-1", "name": "Transcription elongation factor SPT5", "aln": "---------------------------------------------------------------MSDSEDSNFSEEEDSERSSEAEEAEVEED---QRSAAGS------------------------------------EKEEEPE-EEEEEEEE-YDEEEEEEDDDRPPKKPR---HGGFILDEADVDDEYEDEDQWEDG---AEDILEKEEIEASNIDNVVLDEDRSGARRLQNLWRDQREE---ELGEYYMKKYAKSSVGETVYG-GSDELSDDITQQQLLPGVKDPNLWTVKCKIGEERATAISLMRKFIAYQFTDTP--LQIKSVVAPEHVKGYIYVEAYKQTHVKQAIEGVGNLRLGYWNQQMVPIKEMTDVLKVVK-EVANLKPKSWVRLKRGIYKDDIAQVDYVEPSQNTISLKMIPRIDYDRIKARMS---LKDWFAKRKKFKRPPQRLFDAEKIRSLGGDVASDGDFLIFEGNRYSRKGFLFKSFAMSAVITEGVKPTLSELEKFEDQPEGIDLEVV--TESTGKEREHNFQPGDNVEVCEGELINLQGKVLSVDGNKITIMPKHEDLKDMLEFPAQELRKYFKMGDHVKVIAGRFEGDTGLIVRVEENFVILFSDLTMHELKVLPRDLQLCSETASGVDVGGQHEWGELVQLDPRTVGVIVRLERETFQVLNMHGKVVTVRHQAVTQKKDNRFAVALDSDQNNIHVKDIVKVIDGPHSGREGEIRHLYRSFAFLHCKKLVENGGMFVCKARHLVLAGGSKPRDVTNLTVGGFTPMSPRISSPMHPSAEG--------------------------------------------------------------------------------QHGGFGSPGG----MSRGRGRRDNELIGQTVRISQGPYKGYIGVVKDATESTARVELHSTCQTISVDRQRLTTVDSQRPGGMTSTYG----RTPMYGSQTPMY-GSGSRTPMYGSQTPLQDGSRTPHYGSQTPLHDGSRTPAQSGAWDPNNPNTPSRAEEEYEYAFDDEPTPSPQAYGGTPNPQTPGYPDPSSPQVNPQYNPQTPGTPAMYNTDQFSPYAAPSPQGSYQPSPSPQSYHQVAPSPAGYQNTHSPASYHPTPSPMAYQASPSPSPVGYSPMTPGAPSPGGYNPHTPGSGIEQNSSDWVTTDIQVKVRDTYLDTQIVGQTGVIRSVTGGMCSVYLKDSEKVVSISSEHLEPITPTKNNKVKVILGEDREATGVLLSIDGEDGIIRMDLEDQQIKILNLRFLGKLLEA-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00267-1", "uniprot_id": "SPT5H_HUMAN", "id": "O00267-1", "name": "Transcription elongation factor SPT5", "aln": "---------------------------------------------------------------MSDSEDSNFSEEEDSERSSDGEEAEVDEE---RRSAAGS------------------------------------EKEEEPEDEEEEEEEEEYDEEEEEEDDDRPPKKPR---HGGFILDEADVDDEYEDEDQWEDG---AEDILEKEEIEASNIDNVVLDEDRSGARRLQNLWRDQREE---ELGEYYMKKYAKSSVGETVYG-GSDELSDDITQQQLLPGVKDPNLWTVKCKIGEERATAISLMRKFIAYQFTDTP--LQIKSVVAPEHVKGYIYVEAYKQTHVKQAIEGVGNLRLGYWNQQMVPIKEMTDVLKVVK-EVANLKPKSWVRLKRGIYKDDIAQVDYVEPSQNTISLKMIPRIDYDRIKARMS---LKDWFAKRKKFKRPPQRLFDAEKIRSLGGDVASDGDFLIFEGNRYSRKGFLFKSFAMSAVITEGVKPTLSELEKFEDQPEGIDLEVV--TESTGKEREHNFQPGDNVEVCEGELINLQGKILSVDGNKITIMPKHEDLKDMLEFPAQELRKYFKMGDHVKVIAGRFEGDTGLIVRVEENFVILFSDLTMHELKVLPRDLQLCSETASGVDVGGQHEWGELVQLDPQTVGVIVRLERETFQVLNMYGKVVTVRHQAVTRKKDNRFAVALDSEQNNIHVKDIVKVIDGPHSGREGEIRHLFRSFAFLHCKKLVENGGMFVCKTRHLVLAGGSKPRDVTNFTVGGFAPMSPRISSPMHPSAGG--------------------------------------------------------------------------------QRGGFGSPGGGSGGMSRGRGRRDNELIGQTVRISQGPYKGYIGVVKDATESTARVELHSTCQTISVDRQRLTTVGSRRPGGMTSTYG----RTPMYGSQTPMY-GSGSRTPMYGSQTPLQDGSRTPHYGSQTPLHDGSRTPAQSGAWDPNNPNTPSRAEEEYEYAFDDEPTPSPQAYGGTPNPQTPGYPDPSSPQVNPQYNPQTPGTPAMYNTDQFSPYAAPSPQGSYQPSPSPQSYHQVAPSPAGYQNTHSPASYHPTPSPMAYQASPSPSPVGYSPMTPGAPSPGGYNPHTPGSGIEQNSSDWVTTDIQVKVRDTYLDTQVVGQTGVIRSVTGGMCSVYLKDSEKVVSISSEHLEPITPTKNNKVKVILGEDREATGVLLSIDGEDGIVRMDL-DEQLKILNLRFLGKLLEA-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9DDT5-1", "uniprot_id": "SPT5H_DANRE", "id": "Q9DDT5-1", "name": "Transcription elongation factor SPT5", "aln": "---------------------------------------------------------------MSDSEDSDFSDNQ-SERSSEAEEVEENEEEEEQGSVAGS------------------------------------DKAEEEG--EDLEDEEEYDEEEEE-DDDRPRKKAR---HGGFILDEADVDDEYEDEDPWEDG---AEDILEKEEAEVSNLDHVVLDEDHSGSRRLQNLWRDSREE---ALGEYYMRKYAKSSGGEHFYG-GSEDLSDDITQQQLLPGVKDPNLWTVKCKIGEERATAISLMRKFVAYQCTDTP--LQIKSVVAPEHVKGYIYVEAYKQTHVKAAIEGVGNLRMGFWNQQMVPIKEMTDVLKVVK-EVTNLKPKSWVRLKRGLYKDDIAQVDYVEPSQNTISLKMIPRIDLDRIKARMS---MKDWFAKRKKFKRPPQRLFDAEKIRSLGGEVSHDGDFMIFEANRYSRKGFLFKSFAMSAVITEGVKPTLSELEKFEDQPEGIDLEVV--TETTGKEREHNLQAGDNVEVCEGELINLQGKILSVDGNKITIMPKHEDLKDPLEFPAHELRKYFRMGDHVKVIAGRYEGDTGLIVRVEENFVILFSDLTMHELKVLPRDLQLCSETASGVDAGGQHEWGELVQLDPQTVGVIVRLERETFQVLNMHGKVLTVRHQAVNRRKDNRFAVALDSEQNNIHVKDIVKVIDGPHSGREGEIRHIFRGFAFLHCKKLVENGGMFVCKARHLVLAGGSKPRDVTNFTVGGFAPMSPRISSPMHPGGGGQ------------------------------------------------------------------------------PQRGGGGGGGGG---MGRGRGRRDNDLIGQTVRISQGPYKGYIGVVKDATESTARVELHSTCQTISVDRQRLTTVGGKERQGRSSTHL----RTPMYGSQTPIY-GTGSRTPMYGSQTPLHDGSRTPHYGSQTPLHDGSRTPGQSGAWDPNNPNTPSRPDDEYEFAYDDEPSPSPQGYGGTPNPQTPGYPEVPSPQVNPQYNPQTPGTPAMYNTDQYSPYAAPSPQGSYQPSPSPQSYHQVAPSPVGYQNTHSPASYHPTPSPMAYQASPSPSPVGYSPMTPGAPSPGGYNPHTPGSNIDQASNDWVTTDIMVRVKDTFLDGGVINQTGIIRSVTGGMCSVFLQDTEKVVSISSEHLEPVTPTKNNKVKVILGEDREATGVLLSIDGEDGIVRMEL-DEQLKILNLRFLGKLEV--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V460-1", "uniprot_id": "SPT5H_DROME", "id": "Q9V460-1", "name": "Transcription elongation factor SPT5", "aln": "---------------------------------------------------------------MSDSEVSNMSDSGSEDGSISNKSQRSARSKSRSRSRSGSRGSRSVSRSRSRSQSGHSRSGSESPQRRDNRGKSDESGEEEEEPPGEDIDSEEYDEEENDDHPRKKKKKER---FGGFIIDEAEVDDEVDEDDEWEEG---ANEIG-IVGNEIDELGPTARDIEIR--RRGTNLWDTQKED---EIEEYLRKKYADESIAKRHFGDGGEEMSDEITQQTLLPGIKDPNLWMVKCRIGEEKATALLLMRKYLTYLNTDDP--LQIKSIIAPEGVKGYIYLEAYKQTHVKTCIDNVGNLRMGKWKQEMVPIKEMTDVLKVVK-EQVGLKVKQWVRLKRGLYKDDIAQVDYVDLAQNQVHLKLLPRIDYTRMRGALRTTATESDDSKRKKKRRPAAKPFDPEAVRAIGGEVHSDGDFLLFEGNRYSRKGFLYKNFTMSAILSDGVKPTLAELERFEESPEEVNLEIMG-TVKDDPTMAHSFSMGDNVEVCVGDLENLQAKIVAIDGTMITVMPKHQDLKDPLIFKASELRKYFKTGDHARVLAGRYEGETGLIIRVEPTRVVLVSDLTNHELEVLPRDLQLCSDVATGVDCLGQFQWGDMVQLDSQNVGVIVRLERENFHVLGMNGKCIECKPTALHKRKENRHTVALDADQNQIRRRDVVKVMEGPHAGRSGEIKHLYRSLAFLHCRMYTENGGIFVCKTRHLQLAGGSKTTVSNAGIVGGLGFMSPRIQSPMHPSGGRG-------------------------------------------------------------------------------ARGGARGGRGG------FRVTRDREILGKTIKISGGPYKGAVGIVKDATESTARVELHTSCQTISVDRNHIAIVGVTGKEGSVSTYGRTPARTPGYGAQTPSYTAAGSKTPLVGSQTPNWDTDTRTPYGTMTPSHDGSMTP-RHGAWDPTANTTPAR-NNDFDYSLE-EPSPSP-GY----NPSTPGY------QMTSQFAPQTPGT--LYGSDR-----SYSP---FNPSPSP----------------------APSPYPVGYMNTPSPS--TYSPNTPGGIPQSPYNPQTPGASLDSSMGDWCTTDIEVRIH-THDDTDLVGQTGIIRTVSNGVCSVFLRQEDRSVSIVSEHLAPVLPCNGDEFKIIYGDDRESVGRVLSKDGD---VFVCRINEEIKLLPINFLCKMKSID", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P27692-1", "uniprot_id": "SPT5_YEAST", "id": "P27692-1", "name": "Transcription elongation factor SPT5", "aln": "MSDNSDTNVSMQDHDQQFADPVVVPQSTDTKDENTSDKDTVDSGNVTTTESTERAESTSNIPPLDGEEKEAKSEPQQPEDNAETAATEQVSSSNGPATDDAQATLNTDSSEANEIVKKEEGSDERKRPREEDTKNSDGDTKDEGDNKDEDDDEDDDDDDDDEDDDDEAPTKRRRQERNRFLDIEAEVSDDEDEDEDEEDSELVREGFITHGDDEDDEASAPGARRDDRLHRQLDQDLNKTSEEDAQRLAKELRERYGRSS--SKQYR--AAAQDGYVPQRFLLPSVDTATIWGVRCRPGKEKELIRKLLKKKFNLDRAMGKKKLKILSIFQRDNYTGRIYIEAPKQSVIEKFCNGVPDIYIS--QKLLIPVQELPLLLKPNKSDDVALEEGSYVRIKRGIYKGDLAMVDQISENNLEVMLKIVPRLDYGKFDEIDPTTQQRKSRRPTFAHRAPPQLFNPTMALRLDQANLYKRDDRHFTYKNEDYIDGYLYKSFRIQHVETKNIQPTVEELARFGSKEGAVDLTSVSQSIKKAQAAKVTFQPGDRIEVLNGEQRGSKGIVTRTTKDIATIKLN--GFTTPLEFPISTLRKIFEPGDHVTVINGEHQGDAGLVLMVEQGQVTFMSTQTSREVTITANNLSKSIDTTA---TSSEYALHDIVELSAKNVACIIQAGHDIFKVIDETGKVSTITKGSILSKINTARARVSSVDANGNEIKIGDTIVEKVGSRREGQVLYIQTQQIFVVSKKIVENAGVFVVNPSNVEAVASKDNMLSNKMDLS---KMNPEIISKMGPPSSKT-------------------------------------------------------------------------------FQQPIQSRGGR------------EVALGKTVRIRSAGYKGQLGIVKDVNGDKATVELHSKNKHITIDKHKLTYYNREGGEGIT------------YDELVNRR-GRVPQARMGPSYVSAPRNMATGGIAAGAAATSSGLSGGMTPGWS----------------SFDGGKTPAVNAHGGSGGGGVSSWGG------ASTWGGQGNGGASAWGGAG------------------------------------------GGASAWGGQGTGATSTWGGASAWGNKSSWGGASTWASGGESNGAMSTWGG----TGDRSAYGGASTWGGNNNNKSTRDGGASAWGNQDD----------GNRSAWNNQGNKSNYGGNSTWGGH-----------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :...* . *: : . . . . : .. . :* : :.: *::::: . . .* * . *: **:*.*: :::: *:. : : .: . : *: : *: : : .:*. .* . : . .. :.*: ***.:. ..:* *:*: *:*: *::* . : *:* *:. : .* **:** **: :: :.* :: :. :: ::*::*:. :** * : . *: .:**:***:**.*:* ** :. : : **::**:* :: .. : *. . :* .:: .* : *. .*:*:*.* :. : :..::**: ** :* .. ::* : : . .:. **.:** *: . :. : *: : .:. * * *** *. ***. *: *..:*::**:: ** * :.* * :*: : ..:*. . :.:: .:. ::*:*..:.*. *:: :: *:*:. ** :: : :. : . . : * . : .::: : *.*:: :: *: .: .**.*:** :. :: ..... . :. *.*.* * * * . : . * . :*:*::* . *** :*:***.. ..* ****:. : *::*::::: . * *. . . .:: : * .. .: :. ... : .*. : : :*: .: . ...: . : * * :. . . . : :.* :. . . . .. :.*. : . * . : :. . . .. ::. .* .*.: .: : . :.: * * : * ", "identical_positions": 157, "similar_positions": 350, "identity": "12.13%" }, { "cls_id": "homologset.agr.MGI:1202401", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P63076-1", "uniprot_id": "FGF17_RAT", "id": "P63076-1", "name": "Fibroblast growth factor 17", "aln": "MGAARLLPNLTLCLQLLILCCQTQGE-NHPSPNFNQYVRDQGAMTDQLSRRQIREYQLYSRTSGKHVQVTGRRISATAEDGNKFAKLIVETDTFGSRVRIKGAESEKYICMNKRGKLIGKPSGKSKDCVFTEIVLENNYTAFQNARHEGWFMAFTRQGRPRQASRSRQNQREAHFIKRLYQGQLPFPNHAERQKQFEFVGSAPTRRTKRTRRPQSQT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P63075-1", "uniprot_id": "FGF17_MOUSE", "id": "P63075-1", "name": "Fibroblast growth factor 17", "aln": "MGAARLLPNLTLCLQLLILCCQTQGE-NHPSPNFNQYVRDQGAMTDQLSRRQIREYQLYSRTSGKHVQVTGRRISATAEDGNKFAKLIVETDTFGSRVRIKGAESEKYICMNKRGKLIGKPSGKSKDCVFTEIVLENNYTAFQNARHEGWFMAFTRQGRPRQASRSRQNQREAHFIKRLYQGQLPFPNHAERQKQFEFVGSAPTRRTKRTRRPQSQT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60258-1", "uniprot_id": "FGF17_HUMAN", "id": "O60258-1", "name": "Fibroblast growth factor 17", "aln": "MGAARLLPNLTLCLQLLILCCQTQGE-NHPSPNFNQYVRDQGAMTDQLSRRQIREYQLYSRTSGKHVQVTGRRISATAEDGNKFAKLIVETDTFGSRVRIKGAESEKYICMNKRGKLIGKPSGKSKDCVFTEIVLENNYTAFQNARHEGWFMAFTRQGRPRQASRSRQNQREAHFIKRLYQGQLPFPNHAEKQKQFEFVGSAPTRRTKRTRRPQPLT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6SJP8-1", "uniprot_id": "FG17_DANRE", "id": "Q6SJP8-1", "name": "Fibroblast growth factor 17", "aln": "MYGINQR-YLYISFHFFVVWCHAQGEKNHPSPNFKQYVREQGSLTDQLSRRQVRVYQLYSRTSGKHVQIRGHRVSATADDGNSYARLYVETDTFGSRVRIKGAESGRYLCMNRRGKLVGKPNGRGRDCIFTEIVLENNYTALENARHEGWFVAFTRKGRPIRASKTRQNQREVHFIKRLHKGPQPFPN-AEQPKHFEFISFPSTRRAKRNRKHQTAS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . . * :.:::::: *::*** *******:****:**::********:* *************: *:*:****:***.:*:* ***************** :*:***:****:***.*:.:**:************::********:****:*** :**::******.******::* **** **: *:***:. ..***:**.*: *. :", "identical_positions": 142, "similar_positions": 54, "identity": "65.44%" }, { "cls_id": "homologset.agr.MGI:1202402", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P70453-1", "uniprot_id": "PDE7A_MOUSE", "id": "P70453-1", "name": "High affinity 3',5'-cyclic-AMP phosphodiesterase 7A", "aln": "----------------------------MGITLIWCLALVLIKWITSKRRGAISYDSSDQTALY------------------------IRMLGDVRVRSRAGFETERRGSHPY------IDFRIFHSQSDIEASVSAR-----------------NIRRLLSFQRYLRSSRVFRGATVCSSLDILDEDYNGQAKCMLEKVGNWNFDIF----LFDRLTNGNSLVSLTFHLFSLHGLIEYFHLDMVKLRRFLVMIQEDYHSQNPYHNAVHAADVTQAMHCYLKEPKLASSVTPWDILLSLIAAATHDLDHPGVNQPFLIKTNHYLATLYKNSSVLENHHWRSAVGLLRESGLFSHLPLESRQEMEAQIGALILATDISRQNEYLSLFRSHLDKGDLHLDDGRHRHLVLQMALKCADICNPCRNWELSKQWSEKVTEEFFHQGDIEKKYHLGVSPLCDRQTESIANIQIG-FMTYLVEPLFTEWARFSDTRLSQTMLGHVGLNKASWKGLQRQQP-SSED-----ANAAFELNSQLLTQENRLS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O08593-1", "uniprot_id": "PDE7A_RAT", "id": "O08593-1", "name": "High affinity 3',5'-cyclic-AMP phosphodiesterase 7A", "aln": "----------------------------------------------------------DQTALY------------------------IRMLGDVRVRSRAGFETERRGSHPY------IDFRIFHAQSEIEASVSAR-----------------NIRRLLSFQRYLRSSRFFRGATVCRSLNILDEDYNGQAKCMLEKVGNWNFDIF----LFDRLTNGNSLVSLTFHLFSLHGLIEYFHLDMVKLRRFLVMIQEDYHSQNPYHNAVHAADVTQAMHCYLKEPKLANSVTPWDILLSLIAAATHDLDHPGVNQPFLIKTNHYLATLYKNTSVLENHHWRSAVGLLRESGLFSHLPLESRHEMEAQIGALILATDISRQNEYLSLFRSHLDKGDLHLDDGRHRHLVLQMALKCADICNPCRNWELSKQWSEKVTEEFFHQGDIEKKYHLGVSPLCDRQTESIANIQIG-FMTYLQEPLFTEWARFSDTRLSQTMLGHVGLNKASWKGLQRQQP-SSED-----ASAAFELNSQLLTQENRLS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q13946-1", "uniprot_id": "PDE7A_HUMAN", "id": "Q13946-1", "name": "High affinity 3',5'-cyclic-AMP phosphodiesterase 7A", "aln": "MEVCYQLPVLPLDRP--VPQHVLSRRGAISFSSSSALFGCPNPRQLSQRRGAISYDSSDQTALY------------------------IRMLGDVRVRSRAGFESERRGSHPY------IDFRIFHSQSEIEVSVSAR-----------------NIRRLLSFQRYLRSSRFFRGTAVSNSLNILDDDYNGQAKCMLEKVGNWNFDIF----LFDRLTNGNSLVSLTFHLFSLHGLIEYFHLDMMKLRRFLVMIQEDYHSQNPYHNAVHAADVTQAMHCYLKEPKLANSVTPWDILLSLIAAATHDLDHPGVNQPFLIKTNHYLATLYKNTSVLENHHWRSAVGLLRESGLFSHLPLESRQQMETQIGALILATDISRQNEYLSLFRSHLDRGDLCLEDTRHRHLVLQMALKCADICNPCRTWELSKQWSEKVTEEFFHQGDIEKKYHLGVSPLCDRHTESIANIQIG-FMTYLVEPLFTEWARFSNTRLSQTMLGHVGLNKASWKGLQREQS-SSED-----TDAAFELNSQLLPQENRLS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FFK5-1", "uniprot_id": "E7FFK5_DANRE", "id": "E7FFK5-1", "name": "Phosphodiesterase", "aln": "MELCYQLPVLPLDRP--VPKHVLSRRGAISFSSSSSLFGAPDPRQLSQRRGAISYDSSDQTALY------------------------IRMLGDVRVRSQVGFEPERRGSHPYL----GIDFRTLHSRAESAGSIPAR-----------------RIRRLFSFQRHLLSSRLLRGAPHLNPLHILDEDYCGQAKCMLEKVGSWNFDIF----LFDRLTNGNSLVFLTFHLLSQYGLIELFQLDMVKVRRFLVLVQEDYHNQNPYHNAVHAADVTQAMHCYLREPKLAQSLTSFDILLGLLAAATHDLDHPGVNQPFLIKTNHYLAALYRNTSVLENHHWRSAVGLLRETELFSHLPAEDSLSIERQLGSLILATDISRQNEYLSRFRTHLDENDLNLGNASHRHFVLQMALKCADICNPCRPWELSKQWSEKVTEEFFHQGDIEKKLKLEISPLCDSEANTIASVQIG-FMTYVVEPLFAEWARFSDTRLSQTMLGHLGLNKASWSTMEPEASGSSEDGESDPARSSEEPSSRALTQGSPES", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P06776-1", "uniprot_id": "PDE2_YEAST", "id": "P06776-1", "name": "3',5'-cyclic-nucleotide phosphodiesterase 2", "aln": "MSTLFLIGIHEIEKSQTIVQNEHYFDRVIELQDLDSLMVALYKDRVSPFPNVHNFETGVSIVLYDPSKFQLSVRQLDVLFKRFFPSFNISAIDHTREENLQRLECVERENSICRNRITRINHWMYHHHDDTPDGINKNSYGTVNGNSVPTQACEANIYTLLLHLNDSKAQHLRKASVPRLIRNIEFMSFLSDPIEKISQEGSHYWNILSTWDFCALSLSTQELIWCGFTLIKKLSKDAKVLIADNKLLLLLFTLESSYHQVNKFHNFRHAIDVMQATWRLCTYLLKDN---PVQTLLLCMAAIGHDVGHPGTNNQLLCNCESEVAQNFKNVSILENFHRELFQQLLSEH--WPQLLSISKKKFD-FISEAILATDMALHSQY---------EDRLMHENPMKQITLISLIIKAADISNVTRTLSISARWAYLITLEFN-DCALLETFHKAHRPEQDCFGDSYKNVDSPKEDLESIQNILVNVTDPDDIIKDHPHIPNGQIFFINTFAEVFFNALSQKFSGLKFLSDNVKINKEYWMKHKKPQ", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .** * :...* .. :* .* . *:. * : : .: . .* *: . . :.:. :.: .* .: .:. :.: *. ::*: : . :.*: * *:. . . : *: :*. ::..**. * :** ** ** ** . . : ** :** **:.***.*: :* : : :* ::* *:***.* . ** * :.:* . .:: :. *****:: :.:* .. * : :: ::.: :*.***.* * .:* :*: :* ** : : :. : * * :: .:: : ::.: : .: .:. : : : . . *.: : ... : . .", "identical_positions": 72, "similar_positions": 144, "identity": "13.28%" }, { "cls_id": "homologset.agr.MGI:1202403", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P43144-1", "uniprot_id": "ACHA9_RAT", "id": "P43144-1", "name": "Neuronal acetylcholine receptor subunit alpha-9", "aln": "MNRPHSCLSFCWMYFAASGIRAVETANGKYAQKLFSDLFEDYSSALRPVEDTDAVLNVTLQVTLSQIKDMDERNQILTAYLWIRQTWHDAYLTWDRDQYDRLDSIRIPSDLVWRPDIVLYNKADDE-SSEPVNTNVVLRYDGLITWDSPAITKSSCVVDVTYFPFDSQQCNLTFGSWTYNGNQVDIFNALDSGDLSDFIEDVEWEVHGMPAVKNVISYGCCSEPYPDVTFTLLLKRRSSFYIVNLLIPCVLISFLAPLSFYLPAASGEKVSLGVTILLAMTVFQLMVAEIMPASENVPLIGKYYIATMALITASTALTIMVMNIHFCGAEARPVPHWAKVVILKYMSRILFVYDVGESCLSP--------------------------------------------------------------RHSQEPEQVTKVYS-----------------------KLPESNLKTSRNKDLSRKKEVR-------KLLKNDLGYQGGI----PQNTDSY----------CARYEALTKNIEYIAKCLKDHKATNSKGSEWKKVAKVIDRFFMWIFFAMVFVMTVLIIARAD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "G3X8Z7-1", "uniprot_id": "G3X8Z7_MOUSE", "id": "G3X8Z7-1", "name": "Neuronal acetylcholine receptor subunit alpha-9", "aln": "MNRPHPCISFCWMYFAASGIKAVETANGKYAQKLFSDLFEDYSNALRPVEDTDAVLNVTLQVTLSQIKDMDERNQILTAYLWIRQTWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDE-SSEPVNTNVVLRYDGLITWDSPAITKSSCVVDVTYFPFDSQQCNLTFGSWTYNGNQVDIFNALDSGDLSDFIEDVEWEVQGMPAVKNVISYGCCSEPYPDVTFTLLLKRRSSFYIVNLLIPCVLISFLAPLSFYLPAASGEKVSLGVTILLAMTVFQLMVAEIMPASENVPLIGKYYIATMALITASTALTIMVMNIHFCGAEARPVPHWAKVVILKYMSRILFVYDVGESCLSP--------------------------------------------------------------RHSQEPEQITKVYG-----------------------KLPGSNLKASRNKDLSRKKELR-------KLLKNDLGYQGGI----PQNTDSY----------CARYEALTKNIEYIAKCLKDHKATNSKGSEWKKVAKVIDRFFMWIFFAMVFVMTVLIIARAD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UGM1-1", "uniprot_id": "ACHA9_HUMAN", "id": "Q9UGM1-1", "name": "Neuronal acetylcholine receptor subunit alpha-9", "aln": "MNWSHSCISFCWIYFAASRLRAAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYLWIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDE-SSEPVNTNVVLRYDGLITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVDIFNALDSGDLSDFIEDVEWEVHGMPAVKNVISYGCCSEPYPDVTFTLLLKRRSSFYIVNLLIPCVLISFLAPLSFYLPAASGEKVSLGVTILLAMTVFQLMVAEIMPASENVPLIGKYYIATMALITASTALTIMVMNIHFCGAEARPVPHWARVVILKYMSRVLFVYDVGESCLSP--------------------------------------------------------------HHSRERDHLTKVYS-----------------------KLPESNLKAARNKDLSRKKDMN-------KRLKNDLGCQGKN----PQEAESY----------CAQYKVLTRNIEYIAKCLKDHKATNSKGSEWKKVAKVIDRFFMWIFFIMVFVMTILIIARAD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PIT7-1", "uniprot_id": "A0A8M9PIT7_DANRE", "id": "A0A8M9PIT7-1", "name": "", "aln": "------MKTIFLVIHISLLLHAVFSAQGRFAQKLLNDLMEGYSNALRPVEDTDKALNVTLQITLSQIKDMDERNQVLTTYLWVRQIWHDAYLSWDKEEYDGLEVIRIPSNLVWRPDIVLYNNADEEDSSGPPDTNVVLRYNGEITWDSPAITKSSCKVDVSYFPFDSQECNLTFGSWTYNGNQVDIAMGMESGDLSDFVDNVEWECHGMPAVKNVIMYGCCSDPYPDITYTVLLKRRSSFYIFNLLLPCFLISFLAPLGFYLPADSGEKVSLGVTVLLALTVFQLMVAESMPPSESVPLIGKYYIATMTMITASTSLTIFIMNIHFCGAEAKPVPHWAKVLIIDYMSKIFFVYEVGENCTTPESDRGPFFSEDPLASLERDGYFDKGFYEDCHLDERIRSQFNGYSHRDHRHGNGYHHKNSSYRQHRHEQQRRTRSSSNSPVRQSSHHPKYTHFIGRDGSEKLPLTSQEKLKDSEISIPEKINGYTYDQGNGYLNGVGYLHDNGYSKTFGADSYNKTTTGTGCVCGKHQKLVRNIEYIANCFREQRGHQAKGAEWKKVAKVMDRFFMWVFFIMVFLMSILVLAKAT", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : . : ::*. :*:*::****:.**:*.**.********* .******:*************:**:***:** ******:**:::** *: *****:***********:**:* ** * :*******:* ****:******** ***:*****.*:***************** .::*******:::**** :********* *****:****:*:*:**********.***:**.********.***** **********:***:********* **.**.************::*****:***::**********:******:*:*:.***:::***:***.* :* :* :* :: *: . *** :. : ::.::* :.:. : *.:* . ::** *.::: *.:******:*:::::. ::**:********:******:** ***:*::*::*:* ", "identical_positions": 305, "similar_positions": 119, "identity": "52.05%" }, { "cls_id": "homologset.agr.MGI:1202709", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q673L6-1", "uniprot_id": "TERT_RAT", "id": "Q673L6-1", "name": "Telomerase reverse transcriptase", "aln": "MPRAPRCPAVRSLLRSRYREVWPLATFVRRLGLEGSRLVQPGDPKVFRTLVAQCLVCVPWGSQPPPADLSFHQVSSLKELVSRVVQKLCERGERNVLAFGFALLNGARGGPPMAFTTSVHSYLPNSVTESLCVSGAWMLLLSRVGDDLLVYLLSHCALYLLVPPSCAYQVCGSPLYQICATTDTWSSVPAGYRPTRPVGGNFTNLGSAHQIKNSGHQEAPKPQALPSRGTKRLLSLTSTNVPSAKKARFEPALRVDKGPHRQVVPTPSGKTWAPSP---AASPKVPPAAKNLSLKGKASDPSLSG-SVCCKHKPSSSSLLSSP-PQDAEKLRPFTETRHFLYSRGGGQEELNPSFLLNSLPPSLTGARRLVEIIFLGSRPRTSGPFCRTRRLPRRYWQMRPLFQQLLMNHAKCQYVRFLRSHCRFRTAN---------------QRVPDAMDTSPSHLTSLLRLHSSPWQVYGFLRACLRELVPAGLWGTRHNERRFLKNVKKFISLGKYAKLSLQELMWRVKVEDCHWLRSSPEKDTVPAAEHRLRERILAMFLFWLMDTYVVQLLRSFFYITETTFQKNRLFFYRKSVWSKLQSIGIRQQLERVQLRELSQEEVKHHQDTWLAMPICRLRFIPKLNGLRPIVNMSYGMDTRAFGKKKQTQCFTQSLKTLFSVLNYERTKHPNLMG--ASVLGTSDSYRIWRTFVLRVRALDQTPRMYFVKADVTGAYDAIPQDKLVEIVANIIRRSESMYCIRQYAVVQKDSQGQVHKSFRRQVSTLSDLQPYMGQFTKHLQDSDASALRNSVVIEQSISMNETGSSLLHFFLRFVRHSVVKIDGRFYVQCQGIPQGSSLSTLLCSLCFG---DMENKLFAEVQQDGLLLRFVDDFLLVTPHLAHAKAFLSTLVHGVPEYGCMINLQKTVVNFPVETGALGGAAPHQLPAHCLFPWCGLLLDTRTLEVFCDYSGYGRTSIKMSLTFQGVSRAGKTMRYKLLSVLRLKCHGLFLDLQVNSLQTVCINIYKIFLLQAYRFHACVIRLPFGQHVRKNHAFFLGIISNLASCCYAILKVKNPGVSLRAKGAPGSFPPEATRWLCYQAFLLKLAAHSVTYKCLLGPLRTAQKQLCRKLPEATMTLLKTAADPALSTDFQTILD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70372-1", "uniprot_id": "TERT_MOUSE", "id": "O70372-1", "name": "Telomerase reverse transcriptase", "aln": "MTRAPRCPAVRSLLRSRYREVWPLATFVRRLGPEGRRLVQPGDPKIYRTLVAQCLVCMHWGSQPPPADLSFHQVSSLKELVARVVQRLCERNERNVLAFGFELLNEARGGPPMAFTSSVRSYLPNTVIETLRVSGAWMLLLSRVGDDLLVYLLAHCALYLLVPPSCAYQVCGSPLYQICATTDIWPSVSASYRPTRPVGRNFTNLRFLQQIKSSSRQEAPKPLALPSRGTKRHLSLTSTSVPSAKKARCYPVPRVEEGPHRQVLPTPSGKSWVPSP---ARSPEVPTAEKDLSSKGKVSDLSLSG-SVCCKHKPSSTSLLSPP-RQNAFQLRPFIETRHFLYSRGDGQERLNPSFLLSNLQPNLTGARRLVEIIFLGSRPRTSGPLCRTHRLSRRYWQMRPLFQQLLVNHAECQYVRLLRSHCRFRTAN---------------QQVTDALNTSPPHLMDLLRLHSSPWQVYGFLRACLCKVVSASLWGTRHNERRFFKNLKKFISLGKYGKLSLQELMWKMKVEDCHWLRSSPGKDRVPAAEHRLRERILATFLFWLMDTYVVQLLRSFFYITESTFQKNRLFFYRKSVWSKLQSIGVRQHLERVRLRELSQEEVRHHQDTWLAMPICRLRFIPKPNGLRPIVNMSYSMGTRALGRRKQAQHFTQRLKTLFSMLNYERTKHPHLMG--SSVLGMNDIYRTWRAFVLRVRALDQTPRMYFVKADVTGAYDAIPQGKLVEVVANMIRHSESTYCIRQYAVVRRDSQGQVHKSFRRQVTTLSDLQPYMGQFLKHLQDSDASALRNSVVIEQSISMNESSSSLFDFFLHFLRHSVVKIGDRCYTQCQGIPQGSSLSTLLCSLCFG---DMENKLFAEVQRDGLLLRFVDDFLLVTPHLDQAKTFLSTLVHGVPEYGCMINLQKTVVNFPVEPGTLGGAAPYQLPAHCLFPWCGLLLDTQTLEVFCDYSGYAQTSIKTSLTFQSVFKAGKTMRNKLLSVLRLKCHGLFLDLQVNSLQTVCINIYKIFLLQAYRFHACVIQLPFDQRVRKNLTFFLGIISSQASCCYAILKVKNPGMTLKAS---GSFPPEAAHWLCYQAFLLKLAAHSVIYKCLLGPLRTAQKLLCRKLPEATMTILKAAADPALSTDFQTILD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14746-1", "uniprot_id": "TERT_HUMAN", "id": "O14746-1", "name": "Telomerase reverse transcriptase", "aln": "MPRAPRCRAVRSLLRSHYREVLPLATFVRRLGPQGWRLVQRGDPAAFRALVAQCLVCVPWDARPPPAAPSFRQVSCLKELVARVLQRLCERGAKNVLAFGFALLDGARGGPPEAFTTSVRSYLPNTVTDALRGSGAWGLLLRRVGDDVLVHLLARCALFVLVAPSCAYQVCGPPLYQLGAATQARPPPHASG-PRRRLG--------CERAWNHSVREAGVPLGLPAPGARRRGGSASRSLPLPKRPRRGAAPEPERTPVGQGSWAHPGRTRGPSDRGFCVVSPARPAEEATSLEGALSGTRHSHPSVGRQHHAGPPSTSRPPRPWDTPCPPVYAETKHFLYSSGD-KEQLRPSFLLSSLRPSLTGARRLVETIFLGSRPWMPGTPRRLPRLPQRYWQMRPLFLELLGNHAQCPYGVLLKTHCPLRAAVTPAAGVCAREKPQGSVAAPEEEDTDPRRLVQLLRQHSSPWQVYGFVRACLRRLVPPGLWGSRHNERRFLRNTKKFISLGKHAKLSLQELTWKMSVRDCAWLRRSPGVGCVPAAEHRLREEILAKFLHWLMSVYVVELLRSFFYVTETTFQKNRLFFYRKSVWSKLQSIGIRQHLKRVQLRELSEAEVRQHREARPALLTSRLRFIPKPDGLRPIVNMDYVVGARTFRREKRAERLTSRVKALFSVLNYERARRPGLLG--ASVLGLDDIHRAWRTFVLRVRAQDPPPELYFVKVDVTGAYDTIPQDRLTEVIASIIK-PQNTYCVRRYAVVQKAAHGHVRKAFKSHVSTLTDLQPYMRQFVAHLQET--SPLRDAVVIEQSSSLNEASSGLFDVFLRFMCHHAVRIRGKSYVQCQGIPQGSILSTLLCSLCYG---DMENKLFAGIRRDGLLLRLVDDFLLVTPHLTHAKTFLRTLVRGVPEYGCVVNLRKTVVNFPVEDEALGGTAFVQMPAHGLFPWCGLLLDTRTLEVQSDYSSYARTSIRASLTFNRGFKAGRNMRRKLFGVLRLKCHSLFLDLQVNSLQTVCTNIYKILLLQAYRFHACVLQLPFHQQVWKNPTFFLRVISDTASLCYSILKAKNAGMSLGAKGAAGPLPSEAVQWLCHQAFLLKLTRHRVTYVPLLGSLRTAQTQLSRKLPGTTLTALEAAANPALPSDFKTILD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q06163-1", "uniprot_id": "TERT_YEAST", "id": "Q06163-1", "name": "Telomerase reverse transcriptase", "aln": "-------------MKILFEFIQDKLDIDLQTNSTYKENLKCGHFNGLDEILTTCFALPNSRKIALPCLP--GDLSHKAVIDHCIIYLLTGELYNNVLTFGYKIARNE------DVNNSLFCHSANVNVTLLKG-AAWKMFHSLVGTYAFVDLLINYTVIQFNG----------------------------------------------QFFTQIVGNRCNEPHLPPKWAQRSSSSSATAAQIKQLTEP-------------------------------------------------------------------------------------VTNKQFLHKLNINSSSFFPYSKILPSSSSIKKLTDLREAIFPTNLVKIP---------QRLKVRINLTLQKLLKRHKRLNYVSILNSICPPLEGT--------------------------VLDLSHLSRQSPKERVLKFIIVILQKLLPQEMFGSKKNKGKIIKNLNLLLSLPLNGYLPFDSLLKKLRLKDFRWLFISDIWFTKHNFEN--LNQLAICFISWLFRQLIPKIIQTFFYCTEISS-TVTIVYFRHDTWNKLITPFIVEYFKTYLVENNVCR--NHNSYTLSNFNHSKMRIIPKKSNNEFRIIAIPCRGADEEEFTIYKENHKNAIQPTQKILEYLRNKRPTSFTKIYSPTQIADRIKEFKQRLLKKFN-NVLPELYFMKFDVKSCYDSIPRMECMRILKDALKNENGFFVRSQYFFNTNTG---VLKLFN-------------------VVNASRVPKPYELYIDNVRTVHLSNQDVINVVEMEIFKTALWVEDKCYIREDGLFQGSSLSAPIVDLVYDDLLEFYSEFKASPSQDTLILKLADDFLIISTDQQQVINIKKLAMGGFQKYNAKANRDKILA------------VSSQSDDDTVIQFCAMHIFVKELEVWKHSSTMNNFHIRS--------KSSKGIFRSLIALFNTRISYKTIDTNLNSTNTVLMQIDHVVKNISECYKSAFKDLSINVTQNMQFHSFLQRIIEMTVSGCPITKCDP------------------------------LIEYEVRFTILNGFLESLSSNTSKFKDNIILLRKEIQHLQAYIYIYIHIVN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: :. : : : . . :: *. ::: *:. . *. ::* : :: * . .***:**: : ...*: .: .* * .** :: ** :* ** . :: : : . : **. ::* . :: : .. .::**:. . .. : * : ..:. * * ** . . : ::. : :** .* . * :*.: * . . * :*. :* *: . * .::. ::*:::*: ::::* : ::** . *.::.* :: :.* ** * *: :.: *: **: : :::::*** ** : . :.::*:..*.** : : : :: :.: .:: : : .::*:*** .. . : .: : .. ::. .:*:* * ::* : * * : :: :*: : *.:**:* **...**:**: . .:: . :: :. : :* . . . * * *. : :: . : *:: ::: :...::... : : .: : .: * : :*: *** **: : .* :. :: .:: * :* *:*::.****:::.. :. : : *. :*.. * * :. . * . :: :*.: : .: *** . * . *: ::.: : .*:.::. : :* ::** :** :* ::. : :::.. *.: : ** * . : .* * . * : * : * * *.: .. .: : : * : *::", "identical_positions": 138, "similar_positions": 320, "identity": "12.0%" }, { "cls_id": "homologset.agr.MGI:1202710", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8M9P894-1", "uniprot_id": "A0A8M9P894_DANRE", "id": "A0A8M9P894-1", "name": "NAD(P)(+)--arginine ADP-ribosyltransferase", "aln": "---------------------MKMMIEALLLIVAAL----------QDHTSAAPVRTIYPLDMAVNSVDDQYKGCTQTMTNKTEN-YYLPKERSASAEFNKTWQDAEANAKKPE----DNLTMSHSVALYVYTNKDSSVYSDFTKATR--TEKQTYISGTFKWYSLHYLLTEAVQILKKTQPR-----CFLTYRGTNLQF--EAQSKEVRLSSFSSSSLNRTVIQAFGNVSCFEIYTCEGANLTKYSKYPEEKEVLIPPYETFNVAAV--KNRTYEKDLWCETVFVLNSTGTRSDLNCGLMN-SGHHASFSNVLLTMSILFLYLNL--------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E7F1D1-1", "uniprot_id": "E7F1D1_DANRE", "id": "E7F1D1-1", "name": "NAD(P)(+)--arginine ADP-ribosyltransferase", "aln": "-------------------MEILCFVEALLLILAALV---------QDHSSTAADGQSFPLDMALSSVDDQYEGCSAEMATLVKT-EFLEKERSASANFNKAWQEAEENSVKPE----DNLTRNHSIAIHIYTNKDAKVYSSLNSATR--TGKHAYTDGTFAWHSLHFLLTDAIQILKKTQDS-----CYLAYRGTSDKF--ELKSEEVRLGSFASSSLDRAVIQEFGNTSCFEIYTCEGADLTKYSKYPEEKEVLIPPYERFRVVAV--RNQTHEEDLWCETVFVLNSSSSMSDLNCALFN-SGHHTAFCKLLLIVLILFYVVFTC-------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1P3J5-1", "uniprot_id": "A0A8M1P3J5_DANRE", "id": "A0A8M1P3J5-1", "name": "NAD(P)(+)--arginine ADP-ribosyltransferase", "aln": "---------------------MLVIIEALLLILAALE---------QDHTAAAVDR-IISLDMAPNSVDDQYKGCRDKMANLVKT-EYLKKEMSNSEKFRRAWKKGEDFVKDQV----DSLTRNNLIAIYVYS--DASVYDDFNSNTR--SDKIEYKKKKYKWYSFHFLLTEAVQVLKKTQKK-----CFSTFRGTKIEFNKNVLNKKVRFGSFVSSSLDRKIASYFGNKSCFEIKTCKGAEVTKYSKLPHEKEVLIPPYEVFKVTAVSIRKNTNKKNLWCDTVFTLKSSGEKSDLDCALFMKSNKTVAKYNVIH-------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1MA10-1", "uniprot_id": "F1MA10_RAT", "id": "F1MA10-1", "name": "NAD(P)(+)--arginine ADP-ribosyltransferase", "aln": "---------------------MALWFPGGQLTLLLLPLLLLLLWVQQTPAGSAEAALKVDVDLTPGSFDDQYRGCSKQVLEELNQGDYFVREIDTHKYYSRAWQKAHLTWLNQATSLPESMTPVHAVAILVFT-LNLNVSSDFAKAMTRASGSPGQYRQSFHFKYLHYYLTSAIQLLRKESSTKNGSPCYRVHHRMKDVNIEANVGSTVRFGQFLSASLLKEETQVSGNQTLFTIFTCLGASVQDFSLR---KEVLIPPYELFEVVSK--------NCSLKGDLINLRSAGNVSRYNCQLLKASSKKCTPAPMVVLCL-CLVSVLISSKSREHRNLPAPF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CRA0-1", "uniprot_id": "NAR4_MOUSE", "id": "Q9CRA0-1", "name": "Ecto-ADP-ribosyltransferase 4", "aln": "---------------------MALWLPGGQLTLLLL------LWVQQTPAGSTEAPLKVDVDLTPDSFDDQYQGCSEQMVEELNQGDYFIKEVDTHKYYSRAWQKAHLTWLNQAKALPESMTPVHAVAIVVFT-LNLNVSSDLAKAMARAAGSPGQYSQSFHFKYLHYYLTSAIQLLRKDSSTKNGSLCYKVYHGMKDVSIGANVGSTIRFGQFLSASLLKEETRVSGNQTLFTIFTCLGASVQDFSLR---KEVLIPPYELFEVVSK--------SGSPKGDLINLRSAGNMSTYNCQLLKACSKKCAPAPVVIGCL-FLVTVVISSKSRAQRNLLAPF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q93070-1", "uniprot_id": "NAR4_HUMAN", "id": "Q93070-1", "name": "Ecto-ADP-ribosyltransferase 4", "aln": "MGPLINRCKKILLPTTVPPATMRIWLLGGLLPFLLL------LSGLQRPTEGSEVAIKIDFDFAPGSFDDQYQGCSKQVMEKLTQGDYFTKDIEAQKNYFRMWQKAHLAWLNQGKVLPQNMTTTHAVAILFYT-LNSNVHSDFTRAMASVARTPQQYERSFHFKYLHYYLTSAIQLLRKDSIMENGTLCYEVHYRTKDVHFNAYTGATIRFGQFLSTSLLKEEAQEFGNQTLFTIFTCLGAPVQYFSLK---KEVLIPPYELFKVINM--------SYHPRGDWLQLRSTGNLSTYNCQLLKASSKKCIPDPIAIASLSFLTSVIIFSKSRV--------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . * . * * : : .*:: .*.****.** : :: :: . : : *:... . :.:* : :*: .:: : .* ..: : . .: : :*: **.*:*:*:* . *: .. . . :*:..* *:** : ** : * * ** ** : :* ********* *.* . : *.*:. * :* *: ..: : ", "identical_positions": 53, "similar_positions": 77, "identity": "15.59%" }, { "cls_id": "homologset.agr.MGI:1202713", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QUT0-1", "uniprot_id": "RHAG_MOUSE", "id": "Q9QUT0-1", "name": "Ammonium transporter Rh type A", "aln": "------------------MRFKFPLMAISLEVAMIVLFGLFVEYETPQNASQKNASHQNASQQ-----------GNTSSSAKKDQFFQLYPLFQDVHVMIFVGFGFLMTFLKKYGFSGVGFNLFLAALGLQWGTIMQG-LLHSHGKEFHFGIYNMINADFSTATVLISFGAVLGKTSPIQMLIMTILEIAVFAGNEYLVTELFEASDTGASMTIHAFGAYFGLAVAGVLYRPGLRCEHPNDE-SVYHSDLFAMIGTLFLWIFWPSFNSAIADPGDHQYRAIVNTYMSLAACVITAYALSSLVERRGRLDMVHIQNATLAGGVAVGTCADMEIPLYAAMTIGSIAGIISVLGYKFFSPLLANKLMIHDTCGVHNLHGLPGVFGGLASIVAISWG-------------------------------MSTAS-MAMQAAALGSSIGSAIVGGLLTGLILKLPIWNQPPDEYCYDDSVSWKVPKFRELDNRFFQHANHNHVEHEV--------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7TNK7-1", "uniprot_id": "RHAG_RAT", "id": "Q7TNK7-1", "name": "Ammonium transporter Rh type A", "aln": "------------------MRFKFSLIALSLEVVMIVSFALFVEYETSQNGSQKSASQQNASQQNAAAQQNASQQGNASSPAKEDQFFQLYPLFQHVHVMIFVGFGFLMTFLKKYGFSGVGFNLFLAALGLQWGTIVQG-LLHSHGLKFPFRIKNMINADFSTATVLISFGAVLGKTSPIQMIIMTILEIAVFAGNEHLVTEIFKASDTGASMTIHAFGAYFGLAVAGVLYRSGLKHGHPNEE-SVYHSDLFAMIGTLFLWMFWPSFNSAIAQPENNQYRAIVNTYMSLAACVITAYALSSLVERRGRLDMVHIQNATLAGGVAVGTCADMEIPLYFAMTIGSIAGIISVLGYKFLSPLLAHKLMIHDTCGVHNLHGLPGVFGGLASIVAISWG-------------------------------KSTVSTMAMQATALGSSIGSAIVGGLVTGLILKLPVWNQPPDEYCFDDSVSWKVPKYRELDNYFFQHVTHNHVEHEV--------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q02094-1", "uniprot_id": "RHAG_HUMAN", "id": "Q02094-1", "name": "Ammonium transporter Rh type A", "aln": "------------------MRFTFPLMAIVLEIAMIVLFGLFVEYETDQTVLEQ---------------------LNITKPTDMGIFFELYPLFQDVHVMIFVGFGFLMTFLKKYGFSSVGINLLVAALGLQWGTIVQG-ILQSQGQKFNIGIKNMINADFSAATVLISFGAVLGKTSPTQMLIMTILEIVFFAHNEYLVSEIFKASDIGASMTIHAFGAYFGLAVAGILYRSGLRKGHENEE-SAYYSDLFAMIGTLFLWMFWPSFNSAIAEPGDKQCRAIVNTYFSLAACVLTAFAFSSLVEHRGKLNMVHIQNATLAGGVAVGTCADMAIHPFGSMIIGSIAGMVSVLGYKFLTPLFTTKLRIHDTCGVHNLHGLPGVVGGLAGIVAVAMG-------------------------------ASNTS-MAMQAAALGSSIGTAVVGGLMTGLILKLPLWGQPSDQNCYDDSVYWKVPKTR---------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A6M3Q9I2-1", "uniprot_id": "A0A6M3Q9I2_DROME", "id": "A0A6M3Q9I2-1", "name": "", "aln": "-------------MHSPAAKVSGYVVLMIVQIIFLVLFWLFVRYEKTALPLAI----------------------DAEDAGSANEHVSKYPQFQDIQVMIFIGFGFLMTFLRKYGYSATGFTLFMAALVVQWAVLMKG-FLHMEGGKISLSLENIIDADIAAAVPLISMGALLGRTTPIQLLCMSVFEVALFAANEYLALHVFSICDCGGSITVHAFGAYFGLAVALMLRPASDQNETGKLEGASYTSDIFAMIGTTFLWVYWPSFNSVLADGAGGE-RAILNTFLSLAAATVTTFVVSALVSHENKLDMVHVQNSTLAGGVAVGTVCNLLLGAHGAVLIGIIAGTVSVLGYRYLTPWMTANLRLHDTCGVHNLHGMPALISAIASAIYASMATVGEYQSELQDIFPAMVGTNGTETKIMGGLGRNATSQAGYQLFGIAVTLLIAIGGGILTGAVLKYTNFRNLKKDEHHQDEHYWEVPAAENKEEYLNMLAKLLDDDAAATNSNSQSAANFNWRPFLLRNWNAIVPANNLYVRGALH-------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53390-1", "uniprot_id": "MEP3_YEAST", "id": "P53390-1", "name": "Ammonium transporter MEP3", "aln": "-----------MARGDGHLWTET---YDSSTVAFMILGAALVFFMVPGLGFLYS---------------------GLARRKSALALIWVVIMATLVGILQWYFWGYSLAFSKTATNNKFIGNLDSFGFRNVYGKISDDSTYPELIYAIFQMMFMCVALSIIAGATAERGKLFPHMVFLFVFATLVYCPITYWIWAPGGWAYQWGVLDWAGGGNIEILSAVAGFVYSYFLGRRKE----NLLINFRPHNVSMVTLGTSILWFGWLLFNAASSLSPNMRSVYAFMNTCLSATTGGMTWCLLDY-RSEKKWSTVGLCSGIICG-LVAATPSSGCITLYGSLIQGIIAGVVCNFATKIKY-----YLKVDDSLDLLAEHGIAGVVGLIFNALFAADWVIGMDG------------TTKHKGGWLTHNWKQMYIQIAYIGASAGYCAVVTAIICFVLGKIPGVHLRVTEEAEALGLDEDQIGEFAYDYVEVRR-DYYQWGVDTDALHTTCNGANSASETNPTEDSQNSSLSSATVSGQNEKSNNPKLHHAKEA---", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P40260-1", "uniprot_id": "MEP1_YEAST", "id": "P40260-1", "name": "Ammonium transporter MEP1", "aln": "----------MESRTTGPLTTET---YDGPTVAFMILGAALVFFMVPGLGFLYS---------------------GLARRKSALALIWVVLMATLVGILQWYFWGYSLAFSKSAPNNKFIGNLDSFGFRNVYGKKFDEDAYPELAYATFQMMFSCVNLSIIAGATAERGRLLPHMVFLFILATIGYCPVTYWIWSPGGWAYQWGVLDWAGGGNIEILSAVSGFVYSWFLGKRNE----KLLINFRPHNVSLVTLGTSILWFGWLLFNSASSLSPNLRSVYAFMNTCLSAITGGMTWCLLDY-RSEKKWSTVGLCSGIISG-LVAATPSSGCITLYGSLIQGIVAGVVCNFATKLKY-----YAKVDDAMDILAEHGVAGVIGLIFNALFGADWVIGMDG------------TTEHEGGWVTHNYKQMYKQIAYIAASIGYTAAVTAIICFVLGYIPGMRLRISEEAEEAGMDEDQIGEFAYDYVEVRR-DYYLWGVDEDSQRSDVN-HRVNNAHLAAERSSSGTNSSSDGNGEMIQSEKILPIHQEDPANR", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P41948-1", "uniprot_id": "MEP2_YEAST", "id": "P41948-1", "name": "Ammonium transporter MEP2", "aln": "MSYNFTGTPTGEGTGGNSLTTDLNTQFDLANMGWIGVASAGVWIMVPGIGLLYS---------------------GLSRKKHALSLLWASMMASAVCIFQWFFWGYSLAFSHNTRGNGFIGTLEFFGFRNVLGAPSSVSSLPDILFAVYQGMFAAVTGALMLGGACERARLFPMMVFLFLWMTIVYCPIACWVWNAEGWLVKLGSLDYAGGLCVHLTSGHGGLVYALILGKRNDPVTRKGMPKYKPHSVTSVVLGTVFLWFGWMFFNGGSAGNATIRAWYSIMSTNLAAACGGLTWMVIDYFRCGRKWTTVGLCSGIIAG-LVGITPAAGFVPIWSAVVIGVVTGAGCNLAVDLKS-----LLRIDDGLDCYSIHGVGGCIGSVLTGIFAADYVNATAGSY----------ISPIDGGWINHHYKQVGYQLAGICAALAWTVTVTSILLLTMNAIPFLKLRLSADEEELGTDAAQIGEFTYEESTAYIPEPIRSKTSAQMPPPHENIDDKIVGNTDAEKNSTPSDASSTKNTDHIV---------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : * . . : :: : :*: ::* :. . .* .: . . : : : . . . : :. : * ... :. .. *:. : .* . . :** :**. * **. : . . . * :: . : * : .. :.* :. * . : :: * ::* . :. :.* . **: . .. : : : . . . . : : . : : * ", "identical_positions": 24, "similar_positions": 90, "identity": "4.36%" }, { "cls_id": "homologset.agr.MGI:1202715", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q498R2-1", "uniprot_id": "Q498R2_RAT", "id": "Q498R2-1", "name": "Transcription factor 21", "aln": "MSTGSLSDVEDLQEVEMLDCDSLKVDSNKEFGTSNESTEEGSNCENGSPQKGRGGLGKRRKAPTKKSPLSGVSQEGKQVQRNAANARERARMRVLSKAFSRLKTTLPWVPPDTKLSKLDTLRLASSYIAHLRQILANDKYENGYIHPVNLTWPFMVAGKPESDLKEVVTASRLCGTTAS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35437-1", "uniprot_id": "TCF21_MOUSE", "id": "O35437-1", "name": "Transcription factor 21", "aln": "MSTGSLSDVEDLQEVEMLDCDSLKVDSNKEFGTSNESTEEGSNCENGSPQKGRGGLGKRRKAPTKKSPLSGVSQEGKQVQRNAANARERARMRVLSKAFSRLKTTLPWVPPDTKLSKLDTLRLASSYIAHLRQILANDKYENGYIHPVNLTWPFMVAGKPENDLKEVVTANRLCGTTAS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43680-1", "uniprot_id": "TCF21_HUMAN", "id": "O43680-1", "name": "Transcription factor 21", "aln": "MSTGSLSDVEDLQEVEMLECDGLKMDSNKEFVTSNESTEESSNCENGSPQKGRGGLGKRRKAPTKKSPLSGVSQEGKQVQRNAANARERARMRVLSKAFSRLKTTLPWVPPDTKLSKLDTLRLASSYIAHLRQILANDKYENGYIHPVNLTWPFMVAGKPESDLKEVVTASRLCGTTAS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q32PV5-1", "uniprot_id": "TCF21_DANRE", "id": "Q32PV5-1", "name": "Transcription factor 21", "aln": "MSTGSISDVDEFHESELLDG-LPKFGSGKDPGTSNESTEDSSNCEGASVSECTG--KRRKSANMRRSAPNGVAQEGKQVQRNAANARERARMRVLSKAFSRLKTTLPWVPPDTKLSKLDTLRLASSYIAHLRQILANDKYENGYIHPVNLTWPFMVAGKPENELKEMLNSTRLCGTTAS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*****:***::::* *:*: *..*.*: *******:.****..* .: * :*:.* ::*. .**:****************************************************************************************.:***::.:.********", "identical_positions": 131, "similar_positions": 32, "identity": "73.18%" }, { "cls_id": "homologset.agr.MGI:1202717", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97887-1", "uniprot_id": "PSN1_RAT", "id": "P97887-1", "name": "Presenilin-1", "aln": "MTEIPAPLS-YFQNAQMSEDSHSSS-VRSQNDNQERQQHHDRQRLDNPESISNGRPQSNFTRQVIEQ-------------------DEE-EDEELTLKYGAKHVIMLFVPVTLCMVVVVATIKSVSFYTRKDGQ-LIYTPFTEDTETVGQRALHSILNAAIMISVIVVMTILLVVLYKYRCYKVIHAWLIVSSLLLLFFFSFIYLGEVFKTYNVAVDYITVALLIWNFGVVGMIAIHWKGPLRLQQAYLIMISALMALVFIKYLPEWTAWLILAVISVYDLVAVLCPKGPLRMLVETAQERNETLFPALIYSSTMVWLVNMAEGDPEAQRRVPKNPKYSTQGTEREETQDTGTG--------------------SDDG------------------------GFSEEWEA-------QRDSHLGPHRSTPESRAAVQELSGS--ILTSEDPEERGVKLGLGDFIFYSVLVGKASATASGDWNTTIACFVAILIGLCLTLLLLAIFKKALPALPISITFGLIFYFATDYLVQPFMDQLAFHQFYI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P49769-1", "uniprot_id": "PSN1_MOUSE", "id": "P49769-1", "name": "Presenilin-1", "aln": "MTEIPAPLS-YFQNAQMSEDSHSSSAIRSQNDSQERQQQHDRQRLDNPEPISNGRPQSN-SRQVVEQ-------------------DEE-EDEELTLKYGAKHVIMLFVPVTLCMVVVVATIKSVSFYTRKDGQ-LIYTPFTEDTETVGQRALHSILNAAIMISVIVIMTILLVVLYKYRCYKVIHAWLIISSLLLLFFFSFIYLGEVFKTYNVAVDYVTVALLIWNFGVVGMIAIHWKGPLRLQQAYLIMISALMALVFIKYLPEWTAWLILAVISVYDLVAVLCPKGPLRMLVETAQERNETLFPALIYSSTMVWLVNMAEGDPEAQRRVPKNPKYNTQRAER-ETQDSGSG--------------------NDDG------------------------GFSEEWEA-------QRDSHLGPHRSTPESRAAVQELSGS--ILTSEDPEERGVKLGLGDFIFYSVLVGKASATASGDWNTTIACFVAILIGLCLTLLLLAIFKKALPALPISITFGLVFYFATDYLVQPFMDQLAFHQFYI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49768-1", "uniprot_id": "PSN1_HUMAN", "id": "P49768-1", "name": "Presenilin-1", "aln": "MTELPAPLS-YFQNAQMSEDNHLSNTVRSQNDNRERQEHNDRRSLGHPEPLSNGRPQGN-SRQVVEQ-------------------DEE-EDEELTLKYGAKHVIMLFVPVTLCMVVVVATIKSVSFYTRKDGQ-LIYTPFTEDTETVGQRALHSILNAAIMISVIVVMTILLVVLYKYRCYKVIHAWLIISSLLLLFFFSFIYLGEVFKTYNVAVDYITVALLIWNFGVVGMISIHWKGPLRLQQAYLIMISALMALVFIKYLPEWTAWLILAVISVYDLVAVLCPKGPLRMLVETAQERNETLFPALIYSSTMVWLVNMAEGDPEAQRRVSKNSKYNAESTER-ESQDTVAE--------------------NDDG------------------------GFSEEWEA-------QRDSHLGPHRSTPESRAAVQELSSS--ILAGEDPEERGVKLGLGDFIFYSVLVGKASATASGDWNTTIACFVAILIGLCLTLLLLAIFKKALPALPISITFGLVFYFATDYLVQPFMDQLAFHQFYI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W6T7-1", "uniprot_id": "PSN1_DANRE", "id": "Q9W6T7-1", "name": "Presenilin-1", "aln": "MADLVQNAANNVLNDGMDTSRHTSSTAAPPSRN---------------EVELNGQPPTAPPPQVVTD-------------------SEEDEDEELTLKYGAKHVIMLFIPVTLCMVVVVATIKSVSFYTQKDGQQLIYTPFREDTETVGQRALHSMLNAIIMISVIVVMTLVLVVLYKYRCYKVIQAWLFFSNLLLLFFFSLIYLGEVFKTYNVAMDYFTLALIIWNFGVVGMICIHWKGPLRLQQAYLIMISALMALVFIKYLPEWTAWLILAAISVYDLLAVLCPKGPLRILVETAQERNEAIFPALIYSSTMVWLFNMADS---AETRNNSSHPVPQQENQVVAMAPTAQA--------------------EDDG------------------------GFTPAWVD-------HQQHQLGPMQSTEESRRQIQEMPSARPPPPADDDEERGVKLGLGDFIFYSMLVGKASATASGDWNTTLACFVAILIGLCLTLLLLAIFKKALPALPISITFGLVFYFATDNLVRPFMDQLAVHQFYI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O02194-1", "uniprot_id": "PSN_DROME", "id": "O02194-1", "name": "Presenilin homolog", "aln": "MAAVNLQASCSSGLASEDDANVGSQIGAAERLERPPRRQQQRNNYGSSNQDQPDAAILAVPNVVMREPCGSRPSRLTGGGGGSGGPPTNEMEEEQGLKYGAQHVIKLFVPVSLCMLVVVATINSISFYNSTDVY-LLYTPFHEQSPEPSVKFWSALANSLILMSVVVVMTFLLIVLYKKRCYRIIHGWLILSSFMLLFIFTYLYLEELLRAYNIPMDYPTALLIMWNFGVVGMMSIHWQGPLRLQQGYLIFVAALMALVFIKYLPEWTAWAVLAAISIWDLIAVLSPRGPLRILVETAQERNEQIFPALIYSSTVVYALVNTVTPQQSQATASSSPSSSNSTTTTRATQNSLASPEAAAASGQRTGNSHPRQNQRDDGSVLATEGMPLVTFKSNLRGNAEAAGFTQEWSANLSERVARRQIEVQSTQSGNAQRSNEYRTVTAPDQNHPDGQEERGIKLGLGDFIFYSVLVGKASS--YGDWTTTIACFVAILIGLCLTLLLLAIWRKALPALPISITFGLIFCFATSAVVKPFMEDLSAKQVFI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: : : . *. . . : . . . *: : : :** *****:*** **:**:***:******:*:***. .* *:**** *:: . : :: *: *::**:*:**::*:**** ***::*:.**:.*.::***:*: :** *::::**:.:** * *::********:.***:*******.***:::***************** :**.**::**:***.*:****:********** :*********:*: . : :: .. . : *** **: * ::: .: . :* .* . : :. ****:***********:******: ***.**:*******************::**************:* ***. :*:***::*: :*.:*", "identical_positions": 219, "similar_positions": 115, "identity": "40.26%" }, { "cls_id": "homologset.agr.MGI:1202722", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ESZ8-1", "uniprot_id": "GTF2I_MOUSE", "id": "Q9ESZ8-1", "name": "General transcription factor II-I", "aln": "MAQVVMSALPAEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTERGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYFCFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPEHYDLATLKWILENKAGISFIIKRPFLEPKKHLGGRVLAAEAERSMLSPSGSCGPIKVKTEPTEDSGISLEMAAVTVKEESEDPDYYQYNIQGP-SETDGVDEKLPLSKALQGSHHSSEGNEGTEVEVPAEDSTQHVPSETSEDPEVEVTIEDDDYSPPTKRLKSTEPPPPPPVPEPANAGKRKVREFNFEKWNARITDLRKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIKKHELLNSTREDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAEALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKRPELLTHSTTEVTQPRTNTPVKEDWNVRITKLRKQVEEIFNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFVVKKPELVVSYLPPGMASKINTKALQSPKRPRSPGSNSKVPEIEVTVEGPNNSSPQTSAVRTPTQTNGSNVPFKPRGREFSFEAWNAKITDLKQKVENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKESTSSKSPPRKINSSPNVNTTASGVEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVIRPFPGLVINNQLVDQNESEGPVIQESAEASQLEVPVTEEIKETDGSSQIKQEPDPTW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5U2Y1-1", "uniprot_id": "GTF2I_RAT", "id": "Q5U2Y1-1", "name": "General transcription factor II-I", "aln": "MAQVAMSALPAEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTERGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKCTTQANRMSVDAVEIETLRKTVEDYFCFCYGKALGKSTVVPVPYEKMLRDQSAVAVQGLPEGVAFKHPEHYDLATLKWILENKAGISFIIKRPFLEPKKHLGGRVMAADADRPMLSPGGSCGPIKVKTEPTEDSGISLEMAAVTVKEESEDPDYYQYNIQG--------------------SHHSSEGNEGAEVEVPAEDSTQHVPSETSEDPEVEVTIEDDDYSPPTKRPKSSEPPPPPPVPEPTNAGKRKVREFNFEKWNARITDLRKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIKKHELLNSTREDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAEALGSTEAKAVPYQKFEAYPNDLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKRPELLTHSTTEVTQPRTNTPVKEDWNVRITKLRKQVEEIFNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFVVKKPELVVSYLPPGMASKINTKALQSPKRPRSPGSNSKVPEIEVTVEGPNNNSPQTSTVRTPTQTNGSNVPFKPRGREFSFEAWNAKITDLKQKVENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKESTSSKSPPRKTNSSPSVNTTASGVEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVIRPFPGLVINNQLVDQNESEGPVIQESAEASQLEVPATEEIKETDGSSQIKQEPDPTW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P78347-1", "uniprot_id": "GTF2I_HUMAN", "id": "P78347-1", "name": "General transcription factor II-I", "aln": "MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTERGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYFCFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGISFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVKEESEDPDYYQYNIQAGPSETDDVDEKQPLSKPLQGSHHSSEGNEGTEMEVPAEDSTQHVPSETSEDPEVEVTIEDDDYSPPSKRPKANELPQPP-VPEPANAGKRKVREFNFEKWNARITDLRKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIKKHELLNSTREDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAEALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKRPELLTHSTTEVTQPRTNTPVKEDWNVRITKLRKQVEEIFNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFVVKKPELVISYLPPGMASKINTKALQSPKRPRSPGSNSKVPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGREFSFEAWNAKITDLKQKVENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKESTSSKSPPRKINSSPNVNTTASGVEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVIRPFPGLVINNQLVDQSESEGPVIQESAEPSQLEVPATEEIKETDGSSQIKQEPDPTW", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****.**:**.***********************************************************************************.*****************************************************.**************:******************************:****:.::*:*.:***.******************************************. **********:*:*********************************:** *:.* * ** ****:**************************************************************************************************************************************************************:*******************************************************************************************************************************************************:*******************************************..****:******************************************************************************************************************************* ****.***************************************************************************************************************************.************.******.*********************", "identical_positions": 943, "similar_positions": 31, "identity": "94.39%" }, { "cls_id": "homologset.agr.MGI:1202729", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A9H4-1", "uniprot_id": "A0A8I6A9H4_RAT", "id": "A0A8I6A9H4-1", "name": "NAD(P)(+)--arginine ADP-ribosyltransferase", "aln": "MGQATARGVIKRKAFPGRQLSLSTTSCPGGKITPAESGNRFESGHHLNVLQRHKRQKRKMKMGHFELVTTLLAAMVLMDVFQVQAEVLDMAENVFDDEYLKCNSRMEMKYIPRMHGEELANDELLQSVWDKAGIQWEAQKAQLSLPKNFKDAYGIALTAYVTEAQDQSPFYHTFNRAVKIAGLSRRRYIYNFPFKAFHFYLVRALQLLRRPCEESYK--NVVYSTSPNISFAFGEQNQARLGNFTLAYSAKPQTANEQR-LLTIQTCFGVAVGKLLNKESEGIVLIPLSEVFQVSRKGTDDDLILHSINSTCSYYECSFLGGLKAGSCTTNPENPDPGYLNNPDLDSQKLEDSGRKSLDSVKMPE---------IKVLQGEENP--LLPD--EKPEDRNRGKANVPTPGLVPVPGPKSHPSSSSGHRLLPSDTASTILLIAAAVD-FIAL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R2G4-5", "uniprot_id": "NAR3_MOUSE", "id": "Q8R2G4-5", "name": "Ecto-ADP-ribosyltransferase 3", "aln": "-----------------------------------------------------------MKMGHFEMVTTLLAAAVLMDIFQVKAEVLDMAENAFDDEYLKCKSRMESKYIPQMKREEWANDALLRMVWDNAEIQWEARKAQLFLPRNFKDTYGIALTAYVNEAQEQTSFYHTFSSAVKMAGLSRRRYIYNFPFKAFHFYLVRALQLLRRPCEKSYK--TVVYSTSPDISFTFGEQNQARLGNFTLAYSAKPETADNQR-VLTIQTCFGVAVGKFLNKEDDSVVLIPLSEVFQVSRKGTSNDLVLQSINSTCSYYECAFLGGLKTENCIANAEYIDPRYLYNPDMDNQKLEDSGRNNLDPDRMPE---------IKVLQTEENP--LLPD--EKP-DRSRGKANNPTPGLVP--GPKSHPSASSGNTLLPSVMASTILLVASAVN-FIEL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13508-1", "uniprot_id": "NAR3_HUMAN", "id": "Q13508-1", "name": "Ecto-ADP-ribosyltransferase 3", "aln": "-----------------------------------------------------------MKTGHFEIVTMLLATMILVDIFQVKAEVLDMADNAFDDEYLKCTDRMEIKYVPQLLKEEKASHQQLDTVWENAKAKWAARKTQIFLPMNFKDNHGIALMAYISEAQEQTPFYHLFSEAVKMAGQSREDYIYGFQFKAFHFYLTRALQLLRKPCEASSK--TVVYRTSQGTSFTFGGLNQARFGHFTLAYSAKPQAANDQLTVLSIYTCLGVDIENFLDKESERITLIPLNEVFQVSQEGAGNNLILQSINKTCSHYECAFLGGLKTENCIENLEYFQPIYVYNPGEKNQKLEDHSEKNWKLEDHGEKNQKLEDHGVKILEPTQIPGMKIPEPFPLPEDKSQGNINNPTPGPVPVPGPKSHPSASSGKLLLPQFGMVIILISVSAINLFVAL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3APQ8-1", "uniprot_id": "A0A8M3APQ8_DANRE", "id": "A0A8M3APQ8-1", "name": "NAD(P)(+)--arginine ADP-ribosyltransferase", "aln": "----------------------------------------------------------------MERLPAYLLVLLSTIMVQITGKVIEMGMFPEAPDYSFYNCRKEMLQMVTKPG------GLLQTEINNS-------------------------TGFLSMWKNSRPCTKPIPGATSEHMTALQGYVADN-----------AMSLIKNNCTTVYSGAEEEYKTEIGKKVRFKSFFPAKLK--FTDATEDAEVSDDLGTVFSINSCSAIKLDSNGCNSEEMDLLISPTEVFTVEN--------IETVHNSNDNYKHITL-------------------------KHSEFQSKSDCSSLVSSMSK------------------PD-----------------------------ESKESSSSFLSSSLLNMMASLLVVYVFTLTM-----", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* :. * . : :.*: .:*::*. :* . * * : * ::: .::. ::. . : : *.. : . *: . *:.*::. * . * *. . .. * *:: : ..:.::: :::* :* .: : . :..: **. .*** *.. :.:::.: . *: * . .:::. . . : * .*. .*: . ** :: : ", "identical_positions": 33, "similar_positions": 97, "identity": "7.33%" }, { "cls_id": "homologset.agr.MGI:1202864", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9R1J4-1", "uniprot_id": "MYOC_RAT", "id": "Q9R1J4-1", "name": "Myocilin", "aln": "-MPSCAYCCSCGPKMPALQLLFLACLVWGMGARTAQFRKANDRSGRCQYTFTVASPSESSCPREDQAMSAIQDLQRDSSIQHADLESTKARVRSLESLLHQMTSGGVTGTQEVQEGLQGQLGALRRERDQLETQTRDLEVAYNNLLRDKSALEEEKRQLEQENKDLARRLEGSSQEVARLRRGQCPSTHHPSQDMLPGSREVSQWNLDTLAFQELKSELTEVPASQILK-NQSGHPRSKEGDKGCGVLMWVGEPVTLRTAETITGKYGVWMRDPKPTHPYTQETTWRIDTVGTGIRQVFEYSQISQFEQGYPSKVHVLPQALESTGAVVYSGSLYFQGAESRTVLRYELNTETVKAEKEIPGAGYHGQFPYAWGGYTDIDLAVDESGLWVIYSTEETRGAIVLSKLNPENLELESTWETNIRKQSVANAFVICGILYTVSSYSSVHATINFAYDTNTGISKTLTIPFKNRYKYSSMVDYNPLERKLFAWDNFNMVTYDIKLSEM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70624-1", "uniprot_id": "MYOC_MOUSE", "id": "O70624-1", "name": "Myocilin", "aln": "--------------MPALHLLFLACLVWGMGARTAQFRKANDRSGRCQYTFTVASPNESSCPREDQAMSAIQDLQRDSSIQHADLESTKARVRSLESLLHQMTLGRVTGTQEAQEGLQGQLGALRRERDQLETQTRDLEAAYNNLLRDKSALEEEKRQLEQENEDLARRLESSSEEVTRLRRGQCPSTQYPSQDMLPGSREVSQWNLDTLAFQELKSELTEVPASQILKENPSGRPRSKEGDKGCGALVWVGEPVTLRTAETIAGKYGVWMRDPKPTHPYTQESTWRIDTVGTEIRQVFEYSQISQFEQGYPSKVHVLPRALESTGAVVYAGSLYFQGAESRTVVRYELDTETVKAEKEIPGAGYHGHFPYAWGGYTDIDLAVDESGLWVIYSTEEAKGAIVLSKLNPANLELERTWETNIRKQSVANAFVICGILYTVSSYSSAHATVNFAYDTKTGTSKTLTIPFTNRYKYSSMIDYNPLERKLFAWDNFNMVTYDIKLLEM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99972-1", "uniprot_id": "MYOC_HUMAN", "id": "Q99972-1", "name": "Myocilin", "aln": "MRFFCARCCSFGPEMPAVQLLLLACLVWDVGARTAQLRKANDQSGRCQYTFSVASPNESSCPEQSQAMSVIHNLQRDSSTQRLDLEATKARLSSLESLLHQLTLDQAARPQETQEGLQRELGTLRRERDQLETQTRELETAYSNLLRDKSVLEEEKKRLRQENENLARRLESSSQEVARLRRGQCPQTRDTARAVPPGSREVSTWNLDTLAFQELKSELTEVPASRILKESPSGYLRSGEGDTGCGELVWVGEPLTLRTAETITGKYGVWMRDPKPTYPYTQETTWRIDTVGTDVRQVFEYDLISQFMQGYPSKVHILPRPLESTGAVVYSGSLYFQGAESRTVIRYELNTETVKAEKEIPGAGYHGQFPYSWGGYTDIDLAVDEAGLWVIYSTDEAKGAIVLSKLNPENLELEQTWETNIRKQSVANAFIICGTLYTVSSYTSADATVNFAYDTGTGISKTLTIPFKNRYKYSSMIDYNPLEKKLFAWDNLNMVTYDIKLSKM", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ***::**:******.:******:*****:********:****.*****.:.****.*::****** *: ***:****: ********:* . .: .**.***** :**:*************:**.**.*******.*****::*.***::******.**:**:********.*: .:: : ******* *********************:*** . ** ** ***.*** *:*****:********:*************:*****:********* :******. **** ********:**:.*********:*************:****:*****************:***:*************:********:*::********** ***** ***************:*** *******:*..**:****** ** ********.********:******:*******:********* :*", "identical_positions": 388, "similar_positions": 76, "identity": "76.98%" }, { "cls_id": "homologset.agr.MGI:1202875", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P20290-1", "uniprot_id": "BTF3_HUMAN", "id": "P20290-1", "name": "Transcription factor BTF3", "aln": "MRRTGAPAQADSRGRGRARGGCPGGEATLSQPPPRGGTRGQEPQMKETIMNQEKLAKLQAQVRIGGKGTARRKKKVVHRTATADDKKLQFSLKKLGVNNISGIEEVNMFTNQGTVIHFNNPKVQASLAANTFTITGHAETKQLTEMLPSILNQLGADSLTSLRRLAEALPKQS-VDGKAPLATGEDDDDEVPDLVENFDEASKNEAN-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "M0R5M7-1", "uniprot_id": "M0R5M7_RAT", "id": "M0R5M7-1", "name": "Transcription factor BTF3", "aln": "--------------------------------------------MKETIMNQEKLAKLQAQVRIGGKGTARRKKKVVHRTATADDKKLQFSLKKLGVNSISGIEEVNMFTNQGTVIHFNNPKVQASLAANTFTITGHAETKQLTEMLPSILNQLGADSLTSLRRLAEALPKQS-VDGKAPLAAGEEEEDEVPDLVENFDEASKNEAN-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q64152-1", "uniprot_id": "BTF3_MOUSE", "id": "Q64152-1", "name": "Transcription factor BTF3", "aln": "MRRTGAPTQADSRGRGRARGGWPGAEATPSLP--LGGSRGRESQMKETIMNQEKLAKLQAQVRIGGKGTARRKKKVVHRTATADDKKLQFSLKKLGVNNISGIEEVNMFTNQGTVIHFNNPKVQASLAANTFTITGHAETKQLTEMLPSILNQLGADSLTSLRRLAEALPKQS-VDGKAPLATGEDDDDEVPDLVENFDEASKNEAN-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7KM15-1", "uniprot_id": "Q7KM15_DROME", "id": "Q7KM15-1", "name": "Transcription factor BTF3", "aln": "-------------------------------------------------MNAEKLKKLQAQVRIGGKGTPRRKKKIVHSTPATDDKKLQSSLKKLSVNTIPGIEEVNIIKNDGTVIHFNNPKAQASLPTNTFAITGHGENKTITEMVPGILTQLGPQDINQLKKLATEIASKSGAGGAAGSSAADAGDDDVPDLVENFEEVAIADTKEEKSGEVAASA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40314-1", "uniprot_id": "NACB2_YEAST", "id": "P40314-1", "name": "Nascent polypeptide-associated complex subunit beta-2", "aln": "--------------------------------------------MPVDQEKLAKLHKLSAANKVGGTRRKINKKGNLYNNNDKDNTKLQAELHKLHPMTIENVAEANFFKKNGKVLHFNSAVVQIAPQCNLTMIHGQPKENTLNGLYPSVASQLGSQELEYLTGLAHNLENEQ----TVLDQLGDRCSETKQQVMNS---------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q02642-1", "uniprot_id": "NACB1_YEAST", "id": "Q02642-1", "name": "Nascent polypeptide-associated complex subunit beta-1", "aln": "--------------------------------------------MPIDQEKLAKLQKLSANNKVGGTRRKLNKKAGSSAGANKDDTKLQSQLAKLHAVTIDNVAEANFFKDDGKVMHFNKVGVQVAAQHNTSVFYGLPQEKNLQDLFPGIISQLGPEAIQALSQLAAQMEKHE----AKAPADAEKKDEAIPELVEGQTFDADVE-------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ** **.* ::**. .** *:.*** .* ** .* .: *.*::..:*.*:***. .* : * : * : : : : *.: .***.: : * ** : ... .: .: ::::. ", "identical_positions": 34, "similar_positions": 47, "identity": "15.6%" }, { "cls_id": "homologset.agr.MGI:1202876", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZT78-1", "uniprot_id": "A0A8I5ZT78_RAT", "id": "A0A8I5ZT78-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPQLGGGRGGGAGGGGGGSG--AGATSGGDDLG---------ANDELIPFQDEGGEEQEPSSDS---------ASAQRDLD-------------------EVKSSLVNESE------------------NQSSSSDSE-AERRPQ-------------PAR--DAFQKPRDYFAEVRR------PQDGAFFKGPAYPGYPFLMIPDLSSPYLSNGP-----------------LSPGGARTYLQMKWPLLDVPSSATVKDTRSPSPAHLYGDPARWMVP-------PTFRSNKVPVLQHPHHLQ---------------------------------------HPLTPLITYSNDHFSPASPPTHLSPEI-DPKTAGIPRPPHPSELSPYYP-LSPGAVGQIPHPLGWLVPQQGQPMYS--LPPGGFR-------------HPYPALAMNASMSSLVSSRFSPHMVAPAHPGLPTSGIPHPAIVSPIVKQEPAPPSLSPAVSAKSPVTV------------------------KKEEEKKPHVKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRKWHNLSREEQAKYYELARKERQLHAQLYPTWSARDNYG---KKKKRKREKQLSQTQSQQQIQE---------AEGALVSKSKKPCIQYLPPEK---------------------------------PCDSPASSHGSTLDSPATPSAALASPAAPAATHSEQAQPLSLTTKPETRAQLALHSAAFLSAKA-------------------------TASNSSQMGSQPPLLSRPLPLGSMPTALLTSP-PSFPATLHAHQTLPVLQAQPLSLVTKSAH---------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z1J1-1", "uniprot_id": "TF7L1_MOUSE", "id": "Q9Z1J1-1", "name": "Transcription factor 7-like 1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPQLGGGRGG-AGGGGGGSG--AGATSGGDDLG---------ANDELIPFQDEGGEEQEPSSDT---------ASAQRDLD-------------------EVKSSLVNESE------------------NQSSSSDSE-AERRPQ-------------PAR--DAFQKPRDYFAEVRR------PQDGAFFKGGAYPGYPFLMIPDLSSPYLSNGP-----------------LSPGGARTYLQMKWPLLDVPSSATVKDTRSPSPAHLS---------------------NKVPVVQHPHHM----------------------------------------HPLTPLITYSNDHFSPASPPTHLSPEI-DPKTG-IPRPPHPSELSPYYP-LSPGAVGQIPHPLGWLVPQQGQPMYS--LPPGGFR-------------HPYPALAMNASMSSLVSSRF-PHMVAPAHPGLPTSGIPHPAIVSPIVKQEPAAPSLSPAVSAKSPVTV------------------------KKEEEKKPHVKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRKWHNLSREEQAKYYELARKERQLHAQLYPTWSARDNYG---KKKKRKREKQLSQTQSQQQIQE---------AEGALASKSKKPCIQYLPPEK---------------------------------PCDSPASSHGSALDSPATPSAALASPAAPAATHSEQAQPLSLTTKPEARAQLALHSAAFLSAKA-------------------------AASNSSQMGSQPPLLSRPLPLGSMPAALLTSP-PTFPATLHAHQALPVLQAQPLSLVTKSAH---------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HCS4-1", "uniprot_id": "TF7L1_HUMAN", "id": "Q9HCS4-1", "name": "Transcription factor 7-like 1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPQLGGGGGGGGGGSGGGGGSSAGAAGGGDDLG---------ANDELIPFQDEGGEEQEPSSDS---------ASAQRDLD-------------------EVKSSLVNESE------------------NQSSSSDSE-AERRPQ-------------PVR--DTFQKPRDYFAEVRR------PQDSAFFKGPPYPGYPFLMIPDLSSPYLSNGP-----------------LSPGGARTYLQMKWPLLDVPSSATVKDTRSPSPAHLS---------------------NKVPVVQHPHHM----------------------------------------HPLTPLITYSNDHFSPGSPPTHLSPEI-DPKTG-IPRPPHPSELSPYYP-LSPGAVGQIPHPLGWLVPQQGQPMYS--LPPGGFR-------------HPYPALAMNASMSSLVSSRFSPHMVAPAHPGLPTSGIPHPAIVSPIVKQEPAPPSLSPAVSVKSPVTV------------------------KKEEEKKPHVKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRKWHNLSREEQAKYYELARKERQLHSQLYPTWSARDNYG---KKKKRKREKQLSQTQSQQQVQE---------AEGALASKSKKPCVQYLPPEK---------------------------------PCDSPASSHGSMLDSPATPSAALASPAAPAATHSEQAQPLSLTTKPETRAQLALHSAAFLSAKA-------------------------AASSSGQMGSQPPLLSRPLPLGSMPTALLASP-PSFPATLHAHQALPVLQAQPLSLVTKSAH---------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9YHE8-1", "uniprot_id": "T7L1A_DANRE", "id": "Q9YHE8-1", "name": "Transcription factor 7-like 1-A", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPQLNG--------------------GGGDDLG---------ANDELISFKDEG-EQEEKISEN---------VSSERDLD-------------------EVKSSLVNESE------------------NNSSSSDSEQTDRRPR-------------PRPDLESYEKQREYFAEALRR-----QQDGGFFKGPPYAGYPFLMIPDITNPYLSNGS-----------------LSP-STRTYLQMKWPLLDVPASAALKDSRSPTPGHLS---------------------NKVPVVQHPHHV----------------------------------------HPLTPLITYSNEHFSPGTPPSHLSPEILDPKTG-IPRTPHPSELSPYYP-LSPGAVGQIPHPLGWLVPQQGQHMYS--IPPGGFR-------------HPYPALAMNASMSSLVSSRFSPHMVPHPPHGLHQTGIPHPAIVSPAIKQEPNGESPSNSTHGKPSVPV------------------------KKEEEKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHSLSREEQAKYYELARKERQLHSQLYPGWSARDNYG---KRKKRKRD---CKSDSP--------------SESNFSPQPKKQCVPYLSSEK---------------------------------MCDSPTSSHGSMLDSPATPSAALASPAAPAATHSEQAQPLSLTTKPEGRAHHNHPHFPLPGKSS-------------------------GSGSGSSMALH--SLSRPIPFTSLPPSLLGPNSPFHQAALHSHHAL--LQTQPLSLVTKSVE---------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q800Q5-1", "uniprot_id": "T7L1B_DANRE", "id": "Q800Q5-1", "name": "Transcription factor 7-like 1-B", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPQLNG--------------------GGGDELG---------ANDEMISFKDEG-EQEDKISEN---------VSAERGLD-------------------DVKSSLVSESE------------------NNSSSSDSEQTERRPQ-------------PRADLESYEKAREYFTEALRR-----QQDGGFFKSPHYPGYPFLMIPDLANPYLSNGA-----------------LSP-SARTYLQMKWPLLDVPGSAALKDSQSPSPGHLS---------------------NKVPVVQH-AHM----------------------------------------HPLTPLITYSNE-FPPGTPPAHLSPEILDPKTG-IPRTPHPAELSPYYP-LSPGTVGQIPHPLGWLVPQQGQHMYP--ITAGGFR-------------HPYPALAMNASMSSLVSSRFSPHLVPHHPHGLHQTGIPHPAIVSPVIKQEPNGE-LSPPVNTKSPGPN------------------------KKDEDKKPHIKKPLNAFMLYMKEMRAKVVAECTLKENAAINQILGRRWHSLSREEQAKYYELARKERQLHSQLYPGWSARDNYG---KRKKRKRD---NKTDST--------------PED-FSMRSKKPCVQYLPQEK---------------------------------MIDSPGSSHGSMLDSPATPSAALASPAAPAATHSEQAQPLSLTTKPE-----RFPLLSKPPPSS-------------------------SSSSSSSSSSG--LPTPPLLSRPLPFALLTPPSPFHQAALHSHHAL--FQSQPLSLVTKSSD---------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IMA8-1", "uniprot_id": "PANG2_DROME", "id": "Q8IMA8-1", "name": "Protein pangolin, isoform J", "aln": "MPHCGTTNSEINLNSNELISYQKKKSNEDLQKKHDKKCSINLKTSQVPDGGFNNQYTQLTANKIEQYNCNDLDKVCIVPSSRSDGMEASFSELLLSPNKLISQPWQTAEEIENWQNDSFRQRNEMFSCIYTNSMLNQQPCSQQQLLATQLLYARLLRSQLAEREFHSNKFNMVHYSGSKKTMLREDELLSTPSSQDNNNNIKLIKDIENSISCVDPPLFEFSNVHQRAEQKNKQDDKNCYSPKLKSNKEALDGYDLQHTCDFIREQKNILIDIKKKLDNLSDSSGKFRKRLSVRQSHIEVNNGSNSALEESVRRQLNGNRKSIENLLEEVKRLYNQWSSAELYYVRSLQRLGLPSEEDGEYTSTPTHTIMALAAIALSNESILPQKTNAVHSKIPDVESESDFFLTSAKPKTLVEIEDIILQLASSVNMHQSSSASTPHESYSDSVKSDCEESNSAPTCIWHSTRQTFRHKKDVEPCSTAAEIILEYASLSSSSNIETSRLLTSASNLTDVTENYNVTTQLPIVFNYNRESSAESIVTDPLLVPEFSTAPSTPSTGSNSGCSTGMVSGIFGLSQNRRKQRLARHIETLTTNSFKSNAIRGNVDNEITNQLKTSPSIRALPTENVSHLITKTLSSANASLTAQELSITNLFKERLCALQGNAGSMKTEIFPMIDAPYDLSIGSKTKHMNLEAKHTSNAQSNESKETTNDKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHELSREEQSKYYEKARQERQLHMELYPGWSARDNYGYVSKKKKRKKDRSTTDSGGNNMKKCRARFGLDQQSQWCKPCRRKKKCIRYMEALNGNGPAEDGSCFDEHGSQLSDDDEDDYDDDKLGGSCGSADETNKIEDEDSESLNQSMPSPGCLSGLSSLQSPSTTMSLASPLNMNANSATNVIFPASSNALLIVGADQPTAQQRPTLVSTSGSSSGSTSSISTTPNTSSTVSPVTCMTGPCLGSSQERAMMLGNRFSHLGMGLSPPVVSTSTSKSEPFFKPHPTVCNNPIFALPSIGNCSLNISSMPNTSRNPIGANPRDINNPLSINQLTKRREYKNVELIEASESKTIVAHAATSIIQHVAVNGYHANHSLLNSNLGHLHHQLNNRTENPNRSEQTMLSVSNHSVNSSECHKESDSQAIVSSNPPNAGSSDNGVISVS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : .* ... .* .: :: *.: . :: .: * :. ** ::*..* . *: *:.*.* * : ** : :.. . *:.. : :*. : . :. .: *. .. *.: . *:. .:* :::: :*::..*. :::: *.:. * .. ..:* .: : :*. :. : .:. : :: : *: . * .* ... * . : .* .* : :.:: : : . : ...:* * . .:* *::. : . .. * :.: : : : : . . ..::.****:**************************.*********:**.******:**** **:***** :*** ******** *:****:: .: . .: : ** *: *: : .*. .:: :.. : . ::.**.. :. * *: . ::: . .: :.. .. . : :. . * . : . * : *: .:.* ", "identical_positions": 126, "similar_positions": 202, "identity": "10.57%" }, { "cls_id": "homologset.agr.MGI:1202877", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q14129-1", "uniprot_id": "DGCR6_HUMAN", "id": "Q14129-1", "name": "Protein DGCR6", "aln": "-------MERYAGALEEVADGAR-----QQERHYQLLSALQSLVKELPSSFQQRLSYTTLSDLALALLDGTVFEIVQGLLEIQHLTEKSLYNQRLRLQNEHRVLRQALRQKHQEAQQACRPHNLPVLQAAQQRELE---AVEHRIREEQRAMDQKIVLELDRKVADQQSTLEKAGVAGFYVTTNPQELMLQMNLLELIRKLQQRGCWAGKAALGLGGPWQLPAAQCDQKGSPVPP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9BY27-1", "uniprot_id": "DGC6L_HUMAN", "id": "Q9BY27-1", "name": "Protein DGCR6L", "aln": "-------MERYAAALEEVADGAR-----QQERHYQLLSALQSLVKELPSSFQQRLSYTTLSDLALALLDGTVFEIVQGLLEIQHLTEKSLYNQRLRLQNEHRVLRQALRQKHQEAQQACRPHNLPVVQAAQQRELE---AVEHRIREEQRAMDQKIILELDRKVADQQSTLEKAGVAGFYVTTNPQELMLQMNLLELIRKLQQRGCRAGNAALGLGGPWQSPAAQCDQKGSPVPP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F7FP83-1", "uniprot_id": "F7FP83_RAT", "id": "F7FP83-1", "name": "", "aln": "-------MDRYAGAGDEAADRAR-----QQERHYQLLSALQSLVKELPSSFQQRLSYTTLSDLALALLDGTVFEIVQGLLEIQHLTEKSLYNQRLRLQNEHRVLRQTLRQKHLEAQQSCRPHNLPVLQAAQQRELEPWQALEHRIREEQQAMDRKIVLELDRKVADQQSTLEKAGVAGFYVTTNPQELTLQMNLLELIRKLQQRGCQMGKPAL----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35347-1", "uniprot_id": "DGCR6_MOUSE", "id": "O35347-1", "name": "Protein DGCR6", "aln": "-------MDRYAAAGDEAADRAR-----QQERHYQLLSALQSLVKELPSSFQQRLSYTTLSDLALALLDGTVFEIVQGLLEIQHLTEKSLYNQRLRLQNEHRVLRQTLRQKHLEAQQSCRPHNLPVLQAAQQRELE---AMEHRIREEQQAMDRKIVLELDRKVADQQSTLEKAGVAGFYVTTNPQELTLQMNLLELIRKLQQRSCQVGKAAL----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P22468-1", "uniprot_id": "GDL_DROME", "id": "P22468-1", "name": "Gonadal protein gdl", "aln": "MADIPATSEGSANTSEAVVEYQQPTPEFLQRKIYFLVDQLRTYHSELPENLQTRISYDLLTELANCVLNDGIFVIVKALMELQHETERHLIKIRMQAENEYEIEVAEWRSKIKDPEELR--HILGLMKIKHTKKLH--------------ESDTKIIEILDQKVNDQQSTLQKAGVPGFYVTENPKEIKIQMFLLDFILRLSRLKYEPGK-------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * : : ..: : *.: * *:. *:: .***..:* *:** *::** .:*:. :* **:.*:*:** **: * : *:: :**:.: *.* :.:: * * ::: : ::*. * **: **:** ******:****.***** **:*: :** **::* :*.: *: ", "identical_positions": 66, "similar_positions": 62, "identity": "28.09%" }, { "cls_id": "homologset.agr.MGI:1202878", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JV95-1", "uniprot_id": "A0A0G2JV95_RAT", "id": "A0A0G2JV95-1", "name": "", "aln": "-----MATSDVKPKSISRAKKWSEEIENLYRFQQAGYRDEIEYKQVKQVAMVDRWPETGYVKKLQRRDNTFYYYNKQRECEDKEVHKVKIYAY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61845-1", "uniprot_id": "MEIG1_MOUSE", "id": "Q61845-1", "name": "Meiosis-expressed gene 1 protein", "aln": "-----MATSDVKPKSISRAKKWSEEIENLYRFQQAGYRDEIEYKQVKQVAMVDRWPETGYVKKLQRRDNTFFYYNKERECEDKEVHKVKVYVY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5JSS6-1", "uniprot_id": "MEIG1_HUMAN", "id": "Q5JSS6-1", "name": "Meiosis expressed gene 1 protein homolog", "aln": "-----MASSDVKPKSVSHAKKWSEEIENLYRFQQAGYRDETEYRQVKQVSMVDRWPETGYVKKLQRRDNTFYYYNKQRECDDKEVHKVKIYAY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5RGE4-1", "uniprot_id": "MEIG1_DANRE", "id": "Q5RGE4-1", "name": "Meiosis expressed gene 1 protein homolog", "aln": "MACAVLLDNNAKPKSMSRAKQWTGEVENLYRFQQAGYRDELEYRQIKQ-AEIDRWPDTGFVKKLQRRDNTFYYYNRKRECEDREVHKVKVYAY", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .:.****:*:**:*: *:************** **:*:** : :****:**:***********:***::***:*:******:*.*", "identical_positions": 60, "similar_positions": 22, "identity": "64.52%" }, { "cls_id": "homologset.agr.MGI:1202879", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9NQB0-1", "uniprot_id": "TF7L2_HUMAN", "id": "Q9NQB0-1", "name": "Transcription factor 7-like 2", "aln": "MPQLNGGGGDDLGANDELISFKDEGEQEEKSSENSS----------------------------------------------------------------------------------------------------------------------------AERDLADVKSSLVNESETNQNSSSDSEAERRPPPRSES-----------------------------------------------------------------------------------------------------FRDKSRESLEEAAKRQDGGLFKGPP------------------------------------YPGYPFIMIPDLTSPYLPNGSLSPTARTLHFQSGSTHYSAYKTIEHQIAVQYLQMKWPLLDVQAGSLQSRQALKDARSPSPAHIVS------------------------------------------------NKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTG--------IPRPPHPPDISPYYPLSPGTVGQIPHPLGWLVPQQGQ----PVYPITTGGFR-------------HPYPTALTVNASMS-----RFPPHMVPPHHTLHTTGIPHPAIVTP--------------------------TVKQESSQSDVGSLHSSKHQ--DSKKEEEKKK-PHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYG-----KKKKRKRDKQPGETNEHSECFLNPCLSLPPITDLSAPKKCRARFGLDQQNNWCGPCRRKKKCVRYIQGE---------------------------------GSCLSPPSS------DGSLLDSPPPSPNLLGSPP--RDAKSQTEQTQPLSLSLKPDPLA---------------HLSMMPPPPALLLAEATH-KASALCPNGALDLPPAALQP-AAPSSSIAQPSTSSLHSHSSLAGTQP-QPLSLVTKSLE---------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6A9A2-1", "uniprot_id": "A0A8I6A9A2_RAT", "id": "A0A8I6A9A2-1", "name": "", "aln": "MPQLNGGGGDDLGANDELISFKDEGEQEEKNSENSS----------------------------------------------------------------------------------------------------------------------------AERDLADVKSSLVNESETNQNSSSDSEAERRPPPRSES-----------------------------------------------------------------------------------------------------FRDKSRESLEEAAKRQDGGLFKGPP------------------------------------YPGYPFIMIPDLTSPYLPNGSLSPTARTLHFQSGSTHYSAYKTIEHQIAIQYLQMKWPLLDVQAGSLQSRQALKDARSPSPAHIVQSPLPCCTQGHACPHFYTPSDFTVSTQVFRDTKSSHSLQKVGEPWFLESNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTG--------IPRPPHPPDISPYYPLSPGTVGQIPHPLGWLVPQQGQ----PVYPITTGGFR-------------HPYPTALTVNASMS-----RFPPHMVPPHHTLHTTGIPHPAIVTP--------------------------TVKQESSQSDVGSLHSSKHQ--DSKKEEEKKK-PHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYG-----KKKKRKRDKQPGETN-----------------DANTPKKCRALFGLDRQTLWCKPCRRKKKCVRYIQGE---------------------------------GSCLSPPSS------DGSLLDSPPPSPHLLGSPP--QDAKSQTEQTQPLSLSLKPDPLA---------------HLSMMPPPPALLLAEAAHGKASALCPNGALDLPPATLQPSMVPSSSLAQPSTSSLHSHNSLAGTQP-QPLSLVTKSLE---------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q924A0-1", "uniprot_id": "TF7L2_MOUSE", "id": "Q924A0-1", "name": "Transcription factor 7-like 2", "aln": "MPQLNGGGGDDLGANDELISFKDEGEQEEKNSENSS----------------------------------------------------------------------------------------------------------------------------AERDLADVKSSLVNESETNQDSSSDSEAERRPPPRSES-----------------------------------------------------------------------------------------------------FRDKSRESLEEAAKRQDGGLFKGPP------------------------------------YPGYPFIMIPDLTSPYLPNGSLSPTART-----------------------YLQMKWPLLDVQAGSLQSRQTLKDARSPSPAHIVS------------------------------------------------NKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTG--------IPRPPHPPDISPYYPLSPGTVGQIPHPLGWLVPQQGQ----PVYPITTGGFR-------------HPYPTALTVNASMS-----RFPPHMVPPHHTLHTTGIPHPAIVTP--------------------------TVKQESSQSDVGSLHSSKHQ--DSKKEEEKKK-PHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYG-----KKKKRKRDKQPGETNEHSECFLNPCLSLPPITDLSAPKKCRARFGLDQQNNWCGPCSL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AB32U413-1", "uniprot_id": "A0AB32U413_DANRE", "id": "A0AB32U413-1", "name": "", "aln": "MPQLNGGGGDDLGANDEMISFKDEGEQEEKISENSS----------------------------------------------------------------------------------------------------------------------------AERDLADVKSSLVNESETNQNSSSDSEAERRPPPRSES-----------------------------------------------------------------------------------------------------FRDKTRESLEEAAKRQDGGLFKSPP------------------------------------YPGYPFIMIPDLTSPYLPNGSLSPTART-----------------------YLQMKWPLLDVQAGSLQSRQALKDARSPSPAHIVG----------------------------PFCLEFPGQTDLSLHQLQLSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLQADVDPKTG--------IPRPPHPPDISPYYPLSPGTVGQIPHPLGWLVPQQGQ----PVYPITTGGFR-------------HPYPTALTVNASMSSLLSSRFPPHMVPPHHSLHTTGIPHPAIVTP--------------------------NVKQESSHSDIGSLNSSKHQ--DAKKEEEKKKQPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYAGNYQGKKKKRKREKQAGEGNEHREYFPNPCLSLPPITDLSAPKKCRARFGLDQQNNWCGPCRRKKKCIRYIQGE---------------------------------GSCASPPSS------DGSLLESPPSSPSMISPSPSSKESKPQTEQMQPLSLTMKPPPLLSSSQHQ---------HLSMAPPPPLALLDNSGAGKTSGSAHNGSLD--PSDVSSSRSTGSASSRP-ISACHSHSLLPSSAPTQPLSLVTKSID---------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IMA8-1", "uniprot_id": "PANG2_DROME", "id": "Q8IMA8-1", "name": "Protein pangolin, isoform J", "aln": "MPHCGTTNSEINLNSNELISYQKKKSNEDLQKKHDKKCSINLKTSQVPDGGFNNQYTQLTANKIEQYNCNDLDKVCIVPSSRSDGMEASFSELLLSPNKLISQPWQTAEEIENWQNDSFRQRNEMFSCIYTNSMLNQQPCSQQQLLATQLLYARLLRSQLAEREFHSNKFNMVHYSGSKKTMLREDELLSTPSSQDNNNNIKLIKDIENSISCVDPPLFEFSNVHQRAEQKNKQDDKNCYSPKLKSNKEALDGYDLQHTCDFIREQKNILIDIKKKLDNLSDSSGKFRKRLSVRQSHIEVNNGSNSALEESVRRQLNGNRKSIENLLEEVKRLYNQWSSAELYYVRSLQRLGLPSEEDGEYTSTPTHTIMALAAIALSNESILPQKTN----AVHSKIPDVESESDFFLTSAKPKTLVEIEDIILQLASSVNMHQSSSASTPHESYSDSVKSDCEESNSAPTCIWHSTRQTFRHKKDVEPCSTAAEIILEYASLSSSSNIETSRLLTSASNLTDVTENYNVTTQLPIVFNYNRESSAESIVTDPLLVPEFSTAPSTPSTGSNSGCSTGMVSGIFGLSQNRRKQRLARHIETLTTNSFKSNAIRGNVDNEITNQLKTSPSIRALPTENVSHLITKTLSSANASLTAQELSITNLFKERLCALQGNAGSMKTEIFPMIDAPYDLSIGSKTKHMNLEAKHTSNAQSNESKETTNDKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHELSREEQSKYYEKARQERQLHMELYPGWSARDNYG--YVSKKKKRKKDRSTTDSG------------------GNNMKKCRARFGLDQQSQWCKPCRRKKKCIRYMEALNGNGPAEDGSCFDEHGSQLSDDDEDDYDDDKLGGSCGSADETNKIEDEDSESLNQSMPSPGCLSGLSSLQSPSTTMSLASPLNMNANSATNVIFPASSNALLIVGADQPTAQQRPTLVSTSGSSSGSTSSISTTPNTSSTVSPVTCMTGPCLGSSQERAMMLGNRFSHLGMGLSPPVVSTSTSKSEPFFKPHPTVCNNPIFALPSIGNCSLNISSMPNTSRNPIGANPRDINNPLSINQLTKRREYKNVELIEASESKTIVAHAATSIIQHVAVNGYHANHSLLNSNLGHLHHQLNNRTENPNRSEQTMLSVSNHSVNSSECHKESDSQAIVSSNPPNAGSSDNGVISVS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**: . ..: .:*:**::.: .:*: .::.. ***:: . * .:*: * ::: :.* *..:.:. ..: :..:***:.:** .* *. *.. * * *:: *.* *: * . . :: .* * :::: *.*..* .. . :: .: : . : * :::: .. : * : : :..: :*. . .*. .. . * :.* :. :* :: * : .:**..*: : *: ::.* : :. : ..: :* : :. . :.. .: .::.: :: : ::*: * ::*: :.** ****************************************** ******:**** **:******:***********. ******:::.. : . . ***** ****:*. ** ** ", "identical_positions": 144, "similar_positions": 163, "identity": "11.84%" }, { "cls_id": "homologset.agr.MGI:1202880", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B1WC90-1", "uniprot_id": "B1WC90_RAT", "id": "B1WC90-1", "name": "TNF receptor-associated factor", "aln": "----------MPGFDYKFLEKPKRRLLCPLCG--KPMREPVQVSTCGHRFCDTCLQEFLSEGVFKCP----------EDQLPLDYAK--IYPDPELEVQVLGLAIRCIHSEEGCRWSGPLRHLQGHLNTCSFNVVPCPNRCPAKLSRRDLPAHLQHDCPKRRLKCEFCGCDFSGEAYESHEGVCPQESVYCENKCGARMMRRLLAQHATSECPKRTQPCAYCTKEFVYDTIQSHQYQCPRLPVPCPNQCGVGTVAREDLPTHLKDSCSTAFVLCPFKESGCKHRCPKLAMGRHVEESVKPHLAMMCALVSRQRQELQELRRELEELSVGSDGVLIWKIGSYGRRLQEAKAKPNLECFSPAFYTHKYGYKLQVSAFLNGNGSGEGTHLSIYIRVLPGAFDNLLEWPFARRVTFSLLDQSDPGLAKPQHVTETFHPDPNWKNFQKPGTWRGSLDESSLGFGYPKFISHQDIRKRNYVRDDAVFIRASVELPRKILS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61382-1", "uniprot_id": "TRAF4_MOUSE", "id": "Q61382-1", "name": "TNF receptor-associated factor 4", "aln": "----------MPGFDYKFLEKPKRRLLCPLCG--KPMREPVQVSTCGHRFCDTCLQEFLSEGVFKCP----------EDQLPLDYAK--IYPDPELEVQVLGLAIRCIHSEEGCRWSGPLRHLQGHLNTCSFNVVPCPNRCPAKLSRRDLPAHLQHDCPKRRLKCEFCGCDFSGEAYESHEGVCPQESVYCENKCGARMMRRLLAQHATSECPKRTQPCAYCTKEFVYDTIQSHQYQCPRLPVPCPNQCGVGTVAREDLPTHLKDSCSTAFVLCPFKESGCKHRCPKLAMGRHVEESVKPHLAMMCALVSRQRQELQELRRELEELSIGSDGVLIWKIGSYGRRLQEAKAKPNLECFSPAFYTHKYGYKLQVSAFLNGNGSGEGTHLSIYIRVLPGAFDNLLEWPFARRVTFSLLDQSDPGLAKPQHVTETFHPDPNWKNFQKPGTWRGSLDESSLGFGYPKFISHQDIRKRNYVRDDAVFIRASVELPRKILS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BUZ4-1", "uniprot_id": "TRAF4_HUMAN", "id": "Q9BUZ4-1", "name": "TNF receptor-associated factor 4", "aln": "----------MPGFDYKFLEKPKRRLLCPLCG--KPMREPVQVSTCGHRFCDTCLQEFLSEGVFKCP----------EDQLPLDYAK--IYPDPELEVQVLGLPIRCIHSEEGCRWSGPLRHLQGHLNTCSFNVIPCPNRCPMKLSRRDLPAHLQHDCPKRRLKCEFCGCDFSGEAYESHEGMCPQESVYCENKCGARMMRRLLAQHATSECPKRTQPCTYCTKEFVFDTIQSHQYQCPRLPVACPNQCGVGTVAREDLPGHLKDSCNTALVLCPFKDSGCKHRCPKLAMARHVEESVKPHLAMMCALVSRQRQELQELRRELEELSVGSDGVLIWKIGSYGRRLQEAKAKPNLECFSPAFYTHKYGYKLQVSAFLNGNGSGEGTHLSLYIRVLPGAFDNLLEWPFARRVTFSLLDQSDPGLAKPQHVTETFHPDPNWKNFQKPGTWRGSLDESSLGFGYPKFISHQDIRKRNYVRDDAVFIRAAVELPRKILS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9XYR0-1", "uniprot_id": "Q9XYR0_DROME", "id": "Q9XYR0-1", "name": "", "aln": "MVRSLAQWTKTLSFPSRLSPNRNSKDCSTLASPVPPPTPPRNKTTSGSGNCATSRSSSSTVSSSHSSSHSSPTPGNNNNNMPITELEQIIYPGPDPK-HIMGSLVFCIHHKQGCKWSDELRKLKGHLNACKHDATQCPNKCGAQIPRIMMTDHLQYTCTMRRTRCEFCQSEFSGAGLEEHNGSCGQEPVYCEAKCGQRILRGRMTLHKSKDCAKRLRRCAHCQREFSADTLPLHAAQCPRAPLACPQRCDAGPIPRGELEAHLRDECQSLAVSCSFKEAGCRFKGPRQMLEAHLESNAAAHLSLMVALSSRQGQQIQMLKSAVSKLSINYTGTLLWKITDWSAKMAEARGKDGLELVSPPFYTSQYGYKLQASMFLNGNGPGENTHVSVYIKVLPGEYDALLKWPFSHSITFTLFEQG--AQSGQGGVAESFVPDPTWENFQRP-----SNEPDQLGFGFPRFISHELLHSRPFIKGDTVFLRVKVD-PSKIVAV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* :: : : : ..*.. * * : :*.* * *. .. : . :.. ::::*: : ***.*: : :::* : *** ::**:**. **:*:****:*..:. ***:* ::.* :. ***: *. ** :**** .:*** . *.*:* * **.**** *** *::* :: * :.:*.** : *::* :** **: * **** *:.**::*..*.:.* :* **:*.*.: * *.**::**:.: *: : *:*... .**::* ** *** *::* *: :.:**:. *.*:*** .:. :: **:.* .** .**.*** :******.* ******.**.**:*:**:**** :* **:***:: :**:*::*. . : *:*:* ***.*:***:* * : ..****:*:****: ::.* :::.*:**:*. *: * **:: ", "identical_positions": 189, "similar_positions": 164, "identity": "38.18%" }, { "cls_id": "homologset.agr.MGI:1202881", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QZT0-1", "uniprot_id": "CUZD1_RAT", "id": "Q9QZT0-1", "name": "CUB and zona pellucida-like domain-containing protein 1", "aln": "----------------------------------------------------------MEVTGRLFIWAILAVS----CRAQLNSTAAEGRPR-----------------------CTASLGGANLGETHKALILN------------------------------------------------------------------------------------------------------LNADENCTWTIERPENRSIR----------------IIFSHIQLDPD----------------------------SRCENESIKVFDGRSTSGPLLG------EACSKNDFVPVFESSANSLTFQIVTDWTRVQRSVFIFYYFFSSG------------------------------------TTIPNCGGYLQTLEGSFSSPNYPRPHPELAYCVWHIQVEKGYKINLNFTELFLEMDEYCRFDFIAVYDGPSTTSGLLKQVCG--RGTPTFESSSDAMTVVLS------------------------------------TDYAN-------------------------------------------------------------------SYRGFFASYASTYVQEVNTHSLSCASDKMRVIISKSYLQSLNYHESNLQLNDPTCRPSVSN---------------------------------------VVEFSIPLHECGTIKKIEDHT------------------ISYTNIITFTQSPESAVITRKRHLQIVVTCEMEYNSTVEILYITEDDVIQNQSVLGKYNTSMALYESGSFENLIQ----------------------------------------ESPYYVDLNQTLFVQATLHTSD---------PSLVVFLDTCRASP-TSDFASPTYDLISSGCSR--------------------------DETCEVYP-LFGHYGRFQFNAFKFLRHLS-------SVYLKCKILICDTSDHTSRCN-------------------------------QGCVSRRKRDIPSYKWKTDSVIGPIRLKRDRLVNGDSG---------LLPQTHEAEISKQPLSHLHLFSFMVLALNVVIVVTATVRHFLNRWKDHGYQKLQVY---------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70412-1", "uniprot_id": "CUZD1_MOUSE", "id": "P70412-1", "name": "CUB and zona pellucida-like domain-containing protein 1", "aln": "----------------------------------------------------------MEVTGRLFIWAILAVS----CGAQLNSTEAEGKSR-----------------------CTASLGGANLGETHKALVLQ------------------------------------------------------------------------------------------------------LSANENCTWTIERPENRSIR----------------IIFSYIKLDPG----------------------------SRCETENIKVFDGSSTSGPLLG------KACSRNDFVPVFESSSNSMTFQIVTGLTKFPRSVFIFYYFFSAA------------------------------------TVIPNCGGDLRALEGSFSSPNYPKPHPELAYCVWHIQVGKGYKIQLKFTDLLLEMDENCKFDFIAVYDGPSTTAGLLKQLCG--RGKPTLESSSDAMTVVLS------------------------------------TDYAN-------------------------------------------------------------------SYKGFSASYTSIYIHDVNTTSLSCVSDKMRVIISKSYLPALNYNESNLQLNDPTCRPNVSN---------------------------------------VIEFSIPLHECGTVKKIEDHA------------------ISYTNRITFIESPVSAVITRQKLLQIVVTCEMEYNSTVEIMYITEDDIIQNQSVLGKYNTSLALYESDSFENLVQ----------------------------------------ESPYYVDLNQTLFVQATLHTSD---------PSLVVFLDTCRASP-TSDFASPTYDLISSGCCQ--------------------------DETCKVYP-LFGHYGRFQFNAFKFLKHLN-------SVYLKCKILICDNNDQTSRCN-------------------------------QGCVPRRKRDIPSYKWKTDSVIGPIRLKRDRSASRDSG---------LLPQIHEAEISNQPLSRLYLFSFMVLALNVVIVAITTVKHFLNRWMDHRYQKLQVY---------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86UP6-1", "uniprot_id": "CUZD1_HUMAN", "id": "Q86UP6-1", "name": "CUB and zona pellucida-like domain-containing protein 1", "aln": "----------------------------------------------------------MELVRRLMPLTLLILS----CLAELTMAEAEGNAS-----------------------CTVSLGGANMAETHKAMILQ------------------------------------------------------------------------------------------------------LNPSENCTWTIERPENKSIR----------------IIFSYVQLDPD----------------------------GSCESENIKVFDGTSSNGPLLG------QVCSKNDYVPVFESSSSTLTFQIVTDSARIQRTVFVFYYFFSPN------------------------------------ISIPNCGGYLDTLEGSFTSPNYPKPHPELAYCVWHIQVEKDYKIKLNFKEIFLEIDKQCKFDFLAIYDGPSTNSGLIGQVCG--RVTPTFESSSNSLTVVLS------------------------------------TDYAN-------------------------------------------------------------------SYRGFSASYTSIYAENINTTSLTCSSDRMRVIISKSYLEAFNSNGNNLQLKDPTCRPKLSN---------------------------------------VVEFSVPLNGCGTIRKVEDQS------------------ITYTNIITFSASSTSEVITRQKQLQIIVKCEMGHNSTVEIIYITEDDVIQSQNALGKYNTSMALFESNSFEKTIL----------------------------------------ESPYYVDLNQTLFVQVSLHTSD---------PNLVVFLDTCRASP-TSDFASPTYDLIKSGCSR--------------------------DETCKVYP-LFGHYGRFQFNAFKFLRSMS-------SVYLQCKVLICDSSDHQSRCN-------------------------------QGCVSRSKRDISSYKWKTDSIIGPIRLKRDRSASGNSG---------FQHETHAEETPNQPFNSVHLFSFMVLALNVVTVATITVRHFVNQRADYKYQKLQNY---------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PPF9-1", "uniprot_id": "A0A8M9PPF9_DANRE", "id": "A0A8M9PPF9-1", "name": "", "aln": "----------------------------------------------------------MEALTLLLCLLLTTKASLEPCGGSLSSWMGEFTSPNYPNSYPDKARC---------TWTIHSTGAATVSLTFTDVFLESCCDYIR--------------VYNGPSTLYPLLGELVDEKSKSYNSSGNDLTVLFFSDDEISRRGFHANWVFLDSNSCRNYCGFSFGTCSCDDSCQDNRNCCFDYNSYCFQTTTWPTTTDIP----------------SCMYNCGYNPGSCSCTDFCQRDGNCCPDYEAYCSETTTTTTFEPDTTEILSCMYNCGYNLGGCSCTEICRSYGNCCPDYEAYCSETTTTTFEPDTTAHSCMYNCGYDLGSCSCARDCHYYDTCCPDYDSHCPSYTTLRDLTTELHYTESHPKCGGHLYGAG-LFSTPNYPSYYHDNAYCVWYLSAQQGQRIFLTFADVQLER--CCDCDYITIHDGSSTGYPQLGNVCFNDTTHQAFHSTSRYLTVVFR------------------------------------SDFSG-------------------------------------------------------------------VSHGFKAHFTSSLTADQ--GRVDCSSDNMVIVLRRSYLNSLGFSGNDLYVDDRLCRPNISST--------------------------------------EVVFRFPLNTCGTAKKMMNSF------------------VSYTNNVRASPS-QSGVITRQSEFLLSVGCRMEPDTIVQIFYKAEEIPNGNITGTGRFNASIAFYTSRKFNQQIY----------------------------------------DSPYEVFLNDDLFVQVKLTRFD---------ASLDLFLETCVASPNPNDFKDHSYDLLRNGCPR--------------------------DSTFQSYINGVDQYAQFSFRAFKFLQTHA-------YVHLQCKVIICPDNDYNSRCR-------------------------------KGCQYRRKRSLDSSYNTNTVTLGPIKLRGQ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9P0J8-1", "uniprot_id": "A0A8M9P0J8_DANRE", "id": "A0A8M9P0J8-1", "name": "Gypsy retrotransposon integrase-like protein 1", "aln": "MGKKLHGKCVFVIKETETHRTELNRLPGIVGMNVLSELKDLFMTTGDVKKMNRYSCGFKEARVQRVLANIKMQTETLSCNDKIGFVKVAGKQAVTIPPFSERVLEGRCRIPPKVSCQVLVEASSNVSLPKSVLIANVLAKSADGKVPVRVLNSSEKPVKLPPRCRIAALSKPQEVVQKELVEFEEKEGTLYVKAVQKHQVDVDISTTEQLPVPVQMNLENLTESQRCTLQELLVKHSDVFSKNDCDFGYTTAVTHNVPTGDAPPIKQRHRRIPPQVFQEVKKHVQDLVSQGILRESCSPWASPAVIVIKKDGSVRFCCDYRRLNKVTCKDAYPLPRVEESLDALGNAQLFSTLDLTSGYFQVAMSEEDRAKTAVTTPFGLFEWTRMPFGLCNAPATFQRLMGVVLGDLTFDILLIYLDDIIVFSRDFESHCQRLEIVFNRLREHGLKLKPSKCFLLKPEVKFLGHLISSQGIKVDGEKTQVLETWPAPTNVKELRQVLGFMSYYRRFVPCFAQLARPLHALVGKGGKGKVIEPFNWTTECQLAFDKLKHCLMSPPVLAYPDFSQSFVLTTDGSLHGLGAVLSQRQGDAERVIAYASRSLRGSEKNDRNYSAFKLELLALKWAVTEKFKEYLIYSKFSVITDHNPLRYLETANLGAVEQRWVAQLSEFDFEVFYKPGRQNTNADVLSRIPSGEEPEQEDSDKDFIKMNSDEVRTCLWPATKNQQRVQASVQVSVARKVPGYSWSDLEEQQKTDPKIAPIYRAVLKNKNLSPVEQRNMNAELKKLAKQFIRLELKKGVMFRTILDPRDGEEICQLVVPEPLRYKVYESQHDHCGHFGERSTLERMRRNYYWPTMSKDVQSWIKECKRCALAKDVFPKIRAPMTCTNVSAPLEVLAMDYTVLEESVGGYENVLVLTDMFSRFTVAVPTRNQTAHTTAKALVQHWFVHYGCPARLHSDQGRCFEANVIKELCRVYGIGKSRTTPYHPQGNSQCERFNRTMHEMLRTLPPEKKRNWKEYLPELVMAYNSRTHTSTGYSPFYLLFGRDARMPMDILNGRDIEESGVDNLDDWVKKHHDRLKTAVEVANSAAQEASRQRKRAYDRKSRGALMKAGDRVLLRNHSHRGRNKIQDHWEPLPYIVVKQNHTDTPVYTIRPEKGGPCKVVHRDQLRHCTFQSSLPPRTSRHNSRAHTSQEHTDLEDPDVLVVPVTYTPTTLPDTQGRRESGDESDTGIREHDNRISDEDSVDQSVNSGGSEAESENESIPEPRRSQRLNKGTLPVRYRTDFVLK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . : : * .: ..:.:. . . :. : . .. * . . .: : . : .: . . . * . : . : .. . . . *. . . : *. : :. : :: : . . . : :. : . : : .:. .*:: * . : . .:. : . : : : * .* .. : .* . .: . : * . . .* : : . : :* . .:.: . : .::. .:* * : .:: .: : . : : : * :. .. : :: ** . * : .: :*. .::*: :* :: * .. : : : : : . ", "identical_positions": 24, "similar_positions": 149, "identity": "1.87%" }, { "cls_id": "homologset.agr.MGI:1202882", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88298-1", "uniprot_id": "RHD_RAT", "id": "O88298-1", "name": "Blood group Rh(D) polypeptide", "aln": "---------MGSKYPRSLRCCLPLWAFGLQVTFILLFYFLIGQDPIQA----------DHK-FMAIYQVIQDLTLVAALGFGFLSSSFRRHGWS-SVAFSFFMLALGVQGTILLDYFLNWVLDWNMIKNPFSPFLSIQRATISTLPLLISAGAVLGKVNLVQLAVMVLVEAMTFG---AIRVADKKVFRIEDHIIMMYGHVFGAYFGLTVAWWLSKSLPRRRHENAQTEKVQMTTSSSLFAMLGTLFLWIFWPSINSALLEG-TKKKNAVFNTYYALAVSTVTATSMSALSHPKGKINMVHIHNAVLAGGVAVGAPSCLISSPWIAMVLGLTAGLISIWGAKCPQVCLSDLL--LNPSGIHYTFGLPGLLGALTYYCLHIIAESR-------------------------PSNLWIVTQTITDVGALSFAMAMGMVTGLLTGCLLSVKVWRAPHAVKY-FDDQAFWEFPHLAVEF-----------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CF94-1", "uniprot_id": "RHD_MOUSE", "id": "Q8CF94-1", "name": "Blood group Rh(D) polypeptide", "aln": "---------MGSKYPRSLRCCLPLWALELQTAFSLLFCFFIPHDTAQV----------DHR-FMASYQVLRNLTLMAALGFGFLSSSFRRHSWS-SVAFNLFMLALGVQGTILLDHFLGQVLQWNKINN----LSSIQIATMSTLPVLISAGAVLGKVNLVQLTVMVLMEAMAFG---AIRFADEKVFKMTEHIIMMHGHVFGAYFGLTVAWWLSRSLPRRVGENAQTEKVQMATSSSLFAMLGTLFLWIFWPAINSALLEG-TKKRNAVFNTYYALAVSAVTATSMSALSHPQGKINMVHIHNAVLAGGVAVGAPGCLISSPWISMVLGLIAGLISIWGAKCPRACLNHML--QNSSGIHYTFGLPGLLGALTYYCLQIVTEPK-------------------------SSDLWIITQTVTHIGALSFAVAMGMVTGLLTGCLLSVRVWRAPHAAKY-FDDQTFWEFPHLAVGF-----------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P18577-1", "uniprot_id": "RHCE_HUMAN", "id": "P18577-1", "name": "Blood group Rh(CE) polypeptide", "aln": "---------MSSKYPRSVRRCLPLCALTLEAALILLFYFFTHYDASLE----------DQKGLVASYQVGQDLTVMAALGLGFLTSNFRRHSWS-SVAFNLFMLALGVQWAILLDGFLSQFPPGKVVIT----LFSIRLATMSAMSVLISAGAVLGKVNLAQLVVMVLVEVTALG---TLRMVISNIFNTDYHMNLRHFYVFAAYFGLTVAWCLPKPLPKGTEDNDQ-----RATIPSLSAMLGALFLWMFWPSVNSALLRSPIQRKNAMFNTYYALAVSVVTAISGSSLAHPQRKISMTYVHSAVLAGGVAVGTSCHLIPSPWLAMVLGLVAGLISIGGAKCLPVCCNRVLGIHHISVMHSIFSLLGLLGEITYIVLLVLHTVW-------------------------NGNGMIGFQVLLSIGELSLAIVIALTSGLLTGLLLNLKIWKAPHVAKY-FDDQVFWKFPHLAVGF-----------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q02161-1", "uniprot_id": "RHD_HUMAN", "id": "Q02161-1", "name": "Blood group Rh(D) polypeptide", "aln": "---------MSSKYPRSVRRCLPLWALTLEAALILLFYFFTHYDASLE----------DQKGLVASYQVGQDLTVMAAIGLGFLTSSFRRHSWS-SVAFNLFMLALGVQWAILLDGFLSQFPSGKVVIT----LFSIRLATMSALSVLISVDAVLGKVNLAQLVVMVLVEVTALG---NLRMVISNIFNTDYHMNMMHIYVFAAYFGLSVAWCLPKPLPEGTEDKDQ-----TATIPSLSAMLGALFLWMFWPSFNSALLRSPIERKNAVFNTYYAVAVSVVTAISGSSLAHPQGKISKTYVHSAVLAGGVAVGTSCHLIPSPWLAMVLGLVAGLISVGGAKYLPGCCNRVLGIPHSSIMGYNFSLLGLLGEIIYIVLLVLDTVG-------------------------AGNGMIGFQVLLSIGELSLAIVIALMSGLLTGLLLNLKIWKAPHEAKY-FDDQVFWKFPHLAVGF-----------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P53390-1", "uniprot_id": "MEP3_YEAST", "id": "P53390-1", "name": "Ammonium transporter MEP3", "aln": "-----------MARGDGHLWTET---YDSSTVAFMILGAALVFFMVPG----------LGFLYSGLARRKSALALIWVVIMATLVGILQWYFWGYSLAFSKTATNNKFIGNLDSFGFRNVYGKISDDSTYPELIYAIFQMMFMCVALSIIAGATAERGKLFPHMVFLFVFATLVYCPITYWIWAPGGWAYQWGVLDWAGGGNIEILSAVAGFVYSYFLGRRKE----NLLINFRPHNVSMVTLGTSILWFGWLLFNAASSLSPNMRSVYAFMNTCLSATTGGMTWCLLDY-RSEKKWSTVGLCSGIICGLVAATPSSGCIT-LYGSLIQGIIAGVVCNFATKIKYYLKVDDS--LDLLAEHGIAGVVGLIFNALFAADWVIGMDG--TTKHKGGW-------------LTHNWKQMYIQIAYIGASAGYCAVVTAIICFVLGKIPGVHLRVTEEAEALGLDEDQIGEFAYDYVEVRR-DYYQWGVDTDALHTTCNGANSASETNPTEDSQNSSLSSATVSGQNEKSNNPKLHHAKEA---", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P40260-1", "uniprot_id": "MEP1_YEAST", "id": "P40260-1", "name": "Ammonium transporter MEP1", "aln": "----------MESRTTGPLTTET---YDGPTVAFMILGAALVFFMVPG----------LGFLYSGLARRKSALALIWVVLMATLVGILQWYFWGYSLAFSKSAPNNKFIGNLDSFGFRNVYGKKFDEDAYPELAYATFQMMFSCVNLSIIAGATAERGRLLPHMVFLFILATIGYCPVTYWIWSPGGWAYQWGVLDWAGGGNIEILSAVSGFVYSWFLGKRNE----KLLINFRPHNVSLVTLGTSILWFGWLLFNSASSLSPNLRSVYAFMNTCLSAITGGMTWCLLDY-RSEKKWSTVGLCSGIISGLVAATPSSGCIT-LYGSLIQGIVAGVVCNFATKLKYYAKVDDA--MDILAEHGVAGVIGLIFNALFGADWVIGMDG--TTEHEGGW-------------VTHNYKQMYKQIAYIAASIGYTAAVTAIICFVLGYIPGMRLRISEEAEEAGMDEDQIGEFAYDYVEVRR-DYYLWGVDEDSQRSDVN-HRVNNAHLAAERSSSGTNSSSDGNGEMIQSEKILPIHQEDPANR", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P41948-1", "uniprot_id": "MEP2_YEAST", "id": "P41948-1", "name": "Ammonium transporter MEP2", "aln": "MSYNFTGTPTGEGTGGNSLTTDLNTQFDLANMGWIGVASAGVWIMVPG----------IGLLYSGLSRKKHALSLLWASMMASAVCIFQWFFWGYSLAFSHNTRGNGFIGTLEFFGFRNVLGAPSSVSSLPDILFAVYQGMFAAVTGALMLGGACERARLFPMMVFLFLWMTIVYCPIACWVWNAEGWLVKLGSLDYAGGLCVHLTSGHGGLVYALILGKRNDPVTRKGMPKYKPHSVTSVVLGTVFLWFGWMFFNGGSAGNATIRAWYSIMSTNLAAACGGLTWMVIDYFRCGRKWTTVGLCSGIIAGLVGITPAAGFVP-IWSAVVIGVVTGAGCNLAVDLKSLLRIDDG--LDCYSIHGVGGCIGSVLTGIFAADYVNATAGSYISPIDGGW-------------INHHYKQVGYQLAGICAALAWTVTVTSILLLTMNAIPFLKLRLSADEEELGTDAAQIGEFTYEESTAYIPEPIRSKTSAQMPPPHENIDDKIVGNTDAEKNSTPSDASSTKNTDHIV---------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "A0A6M3Q9I2-1", "uniprot_id": "A0A6M3Q9I2_DROME", "id": "A0A6M3Q9I2-1", "name": "", "aln": "------------MHSPAAKVSGYVVLMIVQIIFLVLFWLFVRYEKTALPLAIDAEDAGSANEHVSKYPQFQDIQVMIFIGFGFLMTFLRKYGYS-ATGFTLFMAALVVQWAVLMKGFLHMEGGKISLS-----LENIIDADIAAAVPLISMGALLGRTTPIQLLCMSVFEVALFA---ANEYLALHVFSICDCGGSITVHAFGAYFGLAVALMLRPASDQNETGKLEG----ASYTSDIFAMIGTTFLWVYWPSFNSVLADGAGGER-AILNTFLSLAAATVTTFVVSALVSHENKLDMVHVQNSTLAGGVAVGTVCNLLLGAHGAVLIGIIAGTVSVLGYRYLTPWMTANLRLHDTCGVHNLHGMPALISAIASAIYASMATVGEYQSELQDIFPAMVGTNGTETKIMGGLGRNATSQAGYQLFGIAVTLLIAIGGGILTGAVLKYTNFRNLKKDEH-HQDEHYWEVPAAENKEEYLNMLAKLLDDDAAATNSNSQSAANFNWRPFLLRNWNAIVPANNLYVRGALH------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . : :: :. :: . :. : .*. . : * : : .. : : .. : . . . . :*: :**. * .*. . . : . * : * . : .. :.* *. . : ::: *: :* . . . . . : * . : : . : . : :.. ", "identical_positions": 14, "similar_positions": 72, "identity": "2.59%" }, { "cls_id": "homologset.agr.MGI:1202889", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O70141-1", "uniprot_id": "SEM6B_RAT", "id": "O70141-1", "name": "Semaphorin-6B", "aln": "-----------------------------------------------MWTPRAPPPRPALLFLLLLLLRVTHGLFPDEPPPLSVAPRDYLSHYPVFVG----SGPGRLTPAEGAEDLNIQRVLR-------VNRTLFIGDRDNLYQVELEPSTSTELRYQRKLTWRSNPSDIDVCRMKGKQE-GECRNFVKVLLLRDE--STLFVCGSNAFNP----ICANYS-MDTLQLLGDNISGMARCPYDPKHANVALFSDG-------MLFTATVTDFLAIDAVIYRS--------LGDRPTLRTVKHDSKWFKEPYFVHAVEWGSHVYFFFREIAMEFNYLEKVVVSRVARVCKNDVGGSPRVLEKQWTSFLKARLNCSVPGDSHFYFNVLQAVTGVVSLGGRPVILAVFSTPSNSIPGSAVCAFDMNQVAAVFEGRFREQKSPESIWTPVPEDQVPRPRPGCCAAPGMQYNASNALPDEILNFVKTHPLMDEAVPSLGHSPWIVR---TLIRHQLTRVAVDVGAGPWGNQTIVFLGSEVGTVLKFLVKPNASVSGTTGPSIFLEEFETYRPDRCGRSSSAGEWGQRLLSLELDAASGGLLAAFPRCVVRVPVARCQLYSGCMKNCIGSQDPYCGWAPDG-SCIFLRPGTSATFEQDVSGASTSGLGDCTGLLRASLSDDRAGLVSVNLLVTSSVAAFVVGAVVSGFSVGWFVGLRERRELARRKDKEAILAHGGSEAVLSVSRLGERRGTGTGGRGGAGGG-PGGPPEALLAPLMQNGWTKAALLHGGPHDLDSGLLPTPEQTPLPQKRLPTTHPHAHALGPRAWDHSHALLSASASTSLLLLAHTRAPEQPPVPTESGPESRLCAPRSCRASHPGDFPLTPHASPDRRRVVSAPTGPLDSSSVGDDLPGPWSPPATSSLRRP-GPHGPPTAALRRTHTFNSGEARPGG-HRPRRHAP-ADSTHLLPCGTGERTAPPVP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O54951-1", "uniprot_id": "SEM6B_MOUSE", "id": "O54951-1", "name": "Semaphorin-6B", "aln": "-----------------------------------------------MWTPRVPPPRPALSFFLLLLLGVTYGLFPEEPPPLSVAPRDYLSHYPVFVG----SGPGRLTAAEGAEDLNIQRVLR-------VNRTLFIGDRDNLYQVELEPSTSTELRYQRKLTWRSNPSDIDVCRMKGKQE-GECRNFVKVLLLRDE--STLFVCGSNAFNP----ICANYS-MDTLQLLGDSISGMARCPYDPKHANVALFSDG-------MLFTATVTDFLAIDAVIYRS--------LGDRPTLRTVKHDSKWFKEPYFVHAVEWGSHVYFFFREIAMEFNYLEKVVVSRVARVCKNDVGGSPRVLEKQWTSFLKARLNCSVPGDSHFYFNVLQAVTGVVSLGGRPVILAVFSTPSNSIPGSAVCAFDMNQVAAVFEGRFREQKSPESIWTPVPEDQVPRPRPGCCAAPGMQYNASSALPDEILNFVKTHPLMDEAVPSLGHSPWIVR---TLMRHQLTRVAVDVGAGPWGNQTIVFLGSEAGTVLKFLVKPNASVSGTTGPSIFLEEFETYRPDRCGRPSSAGEWGQRLLSLELDAASGGLLAAFPRCVVRVPVARCQLYSGCMKNCIGSQDPYCGWAPDG-SCIFLRPGTSATFEQDVSGASTSGLGDCTGLLRASLSDDRAGLVSVNLLVTSSVAAFVVGAVVSGFSVGWFVGLRERRELARRKDKEAILAHGGSEAVLSVSRLGERRGTGPGGRGGAGGG-PGGPPEALLAPLMQNGWTKAALLHGGPHDLDTGLLPTPEQTPLPQKRLPTPHPHAHALGSRAWDHSHALLSASASTSLLLLAPARASEQPQVPAEPGPESRLCAPRSCRASHPGDFPLTPHASPDRRRVVSAPTGPLDP-SVGDGLPGPWSPPATSSLRRP-GPHGPPTAALRRTHTFNSGEARPGG-HRPRRHPP-ADSTHLLPCGTGERTAPPVP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H3T3-1", "uniprot_id": "SEM6B_HUMAN", "id": "Q9H3T3-1", "name": "Semaphorin-6B", "aln": "-----------------------------------------------MQTPRASPPRPAL-LLLLLLLGGAHGLFPEEPPPLSVAPRDYLNHYPVFVG----SGPGRLTPAEGADDLNIQRVLR-------VNRTLFIGDRDNLYRVELEPPTSTELRYQRKLTWRSNPSDINVCRMKGKQE-GECRNFVKVLLLRDE--STLFVCGSNAFNP----VCANYS-IDTLQPVGDNISGMARCPYDPKHANVALFSDG-------MLFTATVTDFLAIDAVIYRS--------LGDRPTLRTVKHDSKWFKEPYFVHAVEWGSHVYFFFREIAMEFNYLEKVVVSRVARVCKNDVGGSPRVLEKQWTSFLKARLNCSVPGDSHFYFNVLQAVTGVVSLGGRPVVLAVFSTPSNSIPGSAVCAFDLTQVAAVFEGRFREQKSPESIWTPVPEDQVPRPRPGCCAAPGMQYNASSALPDDILNFVKTHPLMDEAVPSLGHAPWILR---TLMRHQLTRVAVDVGAGPWGNQTVVFLGSEAGTVLKFLVRPNASTSGTSGLSVFLEEFETYRPDRCGRPG-GGETGQRLLSLELDAASGGLLAAFPRCVVRVPVARCQQYSGCMKNCIGSQDPYCGWAPDG-SCIFLSPGTRAAFEQDVSGASTSGLGDCTGLLRASLSEDRAGLVSVNLLVTSSVAAFVVGAVVSGFSVGWFVGLRERRELARRKDKEAILAHGAGEAVLSVSRLGERRAQGPGGRGGGGGGGAGVPPEALLAPLMQNGWAKATLLQGGPHDLDSGLLPTPEQTPLPQKRLPTPHPHPHALGPRAWDHGHPLLPASASSSLLLLAPARAPEQPPAPGEPTPDGRLYAARPGRASH-GDFPLTPHASPDRRRVVSAPTGPLDPASAADGLPRPWSPPPTGSLRRPLGPHAPPAATLRRTHTFNSGEARPGDRHRGCHARPGTDLAHLLPYGGADRTAPPVP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q24323-1", "uniprot_id": "SEM2A_DROME", "id": "Q24323-1", "name": "Semaphorin-2A", "aln": "--------------------------------------------------------MSLLQLSPLLALLLLLCSSVSETAADYENTWNFYYERPCCTGNDQGNNNYGKHGADHVREFNCGKLYYRTFHMNEDRDTLYVGAMDRVFRVNLQN-ISSSNCNRDVINLEPTRDDVVSCVSKGKSQIFDCKNHVRVIQSMDQ-GDRLYVCGTNAHNPKDYVIYANLTHLPRSEYVIGVGLGIAKCPYDPLDNSTAIYVENGNPGGLPGLYSGTNAEFTKADTVIFRTDLYNTSAKRLEYKFKRTLKYDSKWLDKPNFVGSFDIGEYVYFFFRETAVEYINCGKAVYSRIARVCKKDVGGK-NLLAHNWATYLKARLNCSISGEFPFYFNEIQSVYQLPSDKSR--FFATFTTSTNGLIGSAVCSFHINEIQAAFNGKFKEQSSSNSAWLPVLNSRVPEPRPGTCVN------DTSNLPDTVLNFIRSHPLMDKAVNHEHNNPVYYKRDLVFTKLVVDKIRIDILN---QEYIVYYVGTNLGRIYKIVQYYRNGES----LSKLLDIFEVAPN-------------EAIQVMEISQTRKSLYIGTDHRIKQIDLAMCNRRYDNCFRCVR--DPYCGWDKEANTCRPYELDLLQDVANETSDICDS------SVLKKKIVVTYGQSVHLGCFVK-------IPEVLKNEQVTWYHHSKDKGRYEIRYSPTKYIETTERGLVVVSVNEAD------GGR--------------------------------YDCHLGGSLLCSYNITVDAHRCTPPNKSNDYQKIYSDWCHEFEKYKTAMKSWEKKQAQCSTRQN----------------FSSN-QHPNEIFRKPNV-----------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A0B4KG38-1", "uniprot_id": "A0A0B4KG38_DROME", "id": "A0A0B4KG38-1", "name": "Semaphorin-2A", "aln": "MPLNAQLKIAQSVNKVTYAKVSDSNCCAKKQQKYSIADFSQAKRQAGSMCATGKGKHRLCSLSALLLVLVAQTVHVEYARADYENTWNLYYEPPCCTG--SSAAHHLRHHKEHVQDFSCGPLHYKTFYMDERNNALYVGAMDRIFRLNLRN-ISQSICERDVLILEPTGSDILNCVSKGKREKVECRNHIRVIQPMNFNGQKLYVCGTNAHNPKDYVINANLTHLPRSQYVPGIGLGIGKCPYDPADNSTAVYVENGNPFGLPALYAGTNAEFTKADSVIFRSDLYNLTNGRKEANFKRTVKYDSKLLDKPNFVGSFEIGEFVYFFFREHAVEYINCGKAVYSRVARVCKNDRGGK-YMISQNWATYLKARMNCSISSEFPFYFNEIQSVYKMPTDDTK--FYATFTTNTNGLIGSAVCSYDIRDINAAFDGKFKEQATSNSAWLPVLNSKVPEPRPGTCHN------DTATLPDSVLNFIRKHPLMDKAVDHEFGNPVFFKRDVILTKLVVDKIRIDKLN---QEFLVYFVATTSGHIYKIVQFMHYGQR----HSNLVDIFEASPHS------------EPIREMTLSHKTGSLYVATDHQVKQIDIAMCARRYDSCFRCVS--DPYCGWDKDVNACRPYQLGLLQDVANETSGICDT------SVLRKKVTSSYGQTLHLSCFVK-------MPEVLRKKQTRWYHHSTEKGRYEVRYTPTKYIDTNEGGLVLLAVNEGD------GGR--------------------------------YDSYLDGTLLCSYGVTVDAHRCSPPSQKQDYQKIYSHWCNEFEKYKSAMKQWQAKQEQCGLKDKT-------------GPISSNGKHVNDVFSNDALVXPRKYLYSFEFLSSATEGVASAHRKLYIFVFVLTIFARF-------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ** : . . . . : . * .* : . ::. : . :*::* *.:::::*. * . : : ... .*: * *** : :*:*.::*: : . *:***:**.** : ** : : : : . *:.:***** . ..*:: :. *::.* ::* *:**:*: : **:*:*** :.:* ** :.: *..******* *:*: *.* **:*****:* **. :: ::*:::****:***:..: **** :*:* : : : . *.*:* :*.: *****::.: :: *.*:*:*:** :.:* * ** :.:**.**** * : *** :***::.*****:** * : : : : :: :* : : ::.: * : *:: . . * ::: **. : : : :. .* . : : :: :* * . .*: ****** : :* . . ::.*. . : .:*: .: . : :. :*. : *: .. *: :: . * : *: . .: *** *. ** : * .:: *. : : : * : . :: . :: . . .* .:. . ", "identical_positions": 160, "similar_positions": 227, "identity": "16.39%" }, { "cls_id": "homologset.agr.MGI:1202890", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35608-1", "uniprot_id": "ANGP2_MOUSE", "id": "O35608-1", "name": "Angiopoietin-2", "aln": "MWQIIFLTFGWDLVLASAYSNFRKSVDSTGRRQYQVQNGPCSYTFLLPETDSCRSSSSPYMSNAVQRDAPLDYDDSVQRLQVLENILENNTQWLMKLENYIQDNMKKEMVEIQQNVVQNQTAVMIEIGTSLLNQTAAQTRKLTDVEAQVLNQTTRLELQLLQHSISTNKLEKQILDQTSEINKLQNKNSFLEQKVLDMEGKHSEQLQSMKEQKDELQVLVSKQSSVIDELEKKLVTATVNNSLLQKQQHDLMETVNSLLTMMSSPNSKSSVAIRKEEQTTFRDCAEIFKSGLTTSGIYTLTFPN----STEEIKAYCDMDVGGGGWTVIQHRE---DGSVDFQRTWKEYKEGFGSPLGEYWLGNEFVSQLTGQHRYVLKIQLKDWEGNEAHSLYDHFYLAGEESNYRIHLTGLTGTAGKISSISQPGSDFSTKD---SDNDKCICKCSQMLSGGWWFDACGPSNLNGQYYPQKQNTNKFNGIKWYYWKGSGYSLKATTMMIRPADF---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O35462-1", "uniprot_id": "ANGP2_RAT", "id": "O35462-1", "name": "Angiopoietin-2", "aln": "MWQIVFLTFGCDLVLASAYNNFRKSVDSTGRRQYQVQNGPCSYTFLLPETDSCRSSSSPYMSNAVQRDAPLDYDDSVQRLQVLENILENNTQWLMKLENYIQDNMKKEMVEIQQNVVQNQTAVMIEIGTSLLNQTAAQTRKLTDVEAQVLNQTTRLELQLLQHSISTNKLEKQILDQTSEINKLQDKNSFLEKKVLDMEDKHSVQLQSMKEQKDQLQVLVSKQSSVIDELEKKLVTATVNNSVLQKQQHDLMETVNSLLTMMSSPDYKSSVAVPKEEKTTFRDCAEIFKSGLTTSGIYTLTFPN----STEEVKAYCDMDMGGGGWTVIQHRE---DGSVDFQRTWKEYKEGFGSPLGEYWLGNEFVSQLTSGHRYVLKIQLKDWEGSEAHSLYEHFYLSGEESNYRIHLTGLTGTAGKISSISQPGSDFSTKD---SDNDKCICKCSQMLTGGWWFDACGPSNLNGQYYPQKQNTNKFNGIKWYYWKGSGYSLKATTMMIRPADF---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O15123-1", "uniprot_id": "ANGP2_HUMAN", "id": "O15123-1", "name": "Angiopoietin-2", "aln": "MWQIVFFTLSCDLVLAAAYNNFRKSMDSIGKKQYQVQHGSCSYTFLLPEMDNCRSSSSPYVSNAVQRDAPLEYDDSVQRLQVLENIMENNTQWLMKLENYIQDNMKKEMVEIQQNAVQNQTAVMIEIGTNLLNQTAEQTRKLTDVEAQVLNQTTRLELQLLEHSLSTNKLEKQILDQTSEINKLQDKNSFLEKKVLAMEDKHIIQLQSIKEEKDQLQVLVSKQNSIIEELEKKIVTATVNNSVLQKQQHDLMETVNNLLTMMSTSNSAKDPTVAKEEQISFRDCAEVFKSGHTTNGIYTLTFPN----STEEIKAYCDMEAGGGGWTIIQRRE---DGSVDFQRTWKEYKVGFGNPSGEYWLGNEFVSQLTNQQRYVLKIHLKDWEGNEAYSLYEHFYLSSEELNYRIHLKGLTGTAGKISSISQPGNDFSTKD---GDNDKCICKCSQMLTGGWWFDACGPSNLNGMYYPQRQNTNKFNGIKWYYWKGSGYSLKATTMMIRPADF---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VF34-1", "uniprot_id": "Q9VF34_DROME", "id": "Q9VF34-1", "name": "Fibrinogen C-terminal domain-containing protein", "aln": "------------------------------------------------------------------------------------------------------------MMKFSLLFLLAWSCVFLGS-----------TGSLNRIGNSDIGFKSLEELVLIRKTLAAQALKLRGLEIN--LHRVLSKVVLLADAVVQVPGRYSSKEDPLAVLSERLNLLLERLN-----QEERISTNLLELKEWSTKVCQEPSPSQTLPKELTEEKDEPKVDFYQPAKS---DCHELDEG-VRVDGVYRFLVPERNEVQRDLYERYCAFATDGPAWTVIQSRGGSFDPHENFNRSWDEYRAGFGNLSRDFWFGNEFAHKILYRDDHELRIELQEAGEPLDWAEYPLFWLDSESYNYQLSVAGEFRGSLPDALEQHNRMDFSTYDRRRNHAKSADSTCGEDYGGGWWFDRCTQCNLNGEHGVHQRAS---PAIIWMNWRTGTDKPKSSRMMIRPVNPTPGDNSDGD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:::. : :.*:: * .*. : . :. .: ** *:.:::::: *: : *: . :::: .* :* . *: : .:: : :.: .:.*::*:.: . *::: * :: . ..: : .. :.* . :: . . . : : ** *: :. ..*:* : .*: . : : ** : .* .**:** * * :*:*:*.**: ***. ::*:****. :: . : *:*.*:: : * *:* .*. **:: : * : : .: **** * .. ... ..*.: ****** * .**** : ::: : .* * *: . . *:: *****.: ", "identical_positions": 81, "similar_positions": 144, "identity": "15.73%" }, { "cls_id": "homologset.agr.MGI:1202907", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97314-1", "uniprot_id": "CSRP2_MOUSE", "id": "P97314-1", "name": "Cysteine and glycine-rich protein 2", "aln": "----------------MPVWG--GGNKCGACGRTVYHAEEVQCD-----GRSFHRCCFLCMVCRKNLDS----------------------------------------------------------------TTVAIHDEEIYCKSCYGKKYGP--KGYGYGQGAGTLNMDRG----------------------------------------------------------------------------------------------------------------------------ERLGIKP----------------------------------------------------------------------------------ESAQPHRPTTNPNTSKFAQKYG-GAEKCS---------------------------------------------------------------------------------------------------RCGDSVYAAEKIIGAGKP-WHKNCFRCAKCGKSLESTTLTE-----KEGEIYCKGCYAKN-FGPKGFGYGQGAGALVHAQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q62908-1", "uniprot_id": "CSRP2_RAT", "id": "Q62908-1", "name": "Cysteine and glycine-rich protein 2", "aln": "----------------MPVWG--GGNKCGACGRTVYHAEEVQCD-----GRTFHRCCFLCMVCRKNLDS----------------------------------------------------------------TTVAIHDEEIYCKSCYGKKYGP--KGYGYGQGAGTLNMDRG----------------------------------------------------------------------------------------------------------------------------ERLGIKP----------------------------------------------------------------------------------ESAQPHRPTTNPNTSKFAQKYG-GAEKCS---------------------------------------------------------------------------------------------------RCGDSVYAAEKIIGAGKP-WHKNCFRCAKCGKSLESTTLTE-----KEGEIYCKGCYAKN-FGPKGFGYGQGAGALVHAQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q16527-1", "uniprot_id": "CSRP2_HUMAN", "id": "Q16527-1", "name": "Cysteine and glycine-rich protein 2", "aln": "----------------MPVWG--GGNKCGACGRTVYHAEEVQCD-----GRSFHRCCFLCMVCRKNLDS----------------------------------------------------------------TTVAIHDEEIYCKSCYGKKYGP--KGYGYGQGAGTLNMDRG----------------------------------------------------------------------------------------------------------------------------ERLGIKP----------------------------------------------------------------------------------ESVQPHRPTTNPNTSKFAQKYG-GAEKCS---------------------------------------------------------------------------------------------------RCGDSVYAAEKIIGAGKP-WHKNCFRCAKCGKSLESTTLTE-----KEGEIYCKGCYAKN-FGPKGFGYGQGAGALVHAQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q24400-1", "uniprot_id": "MLP2_DROME", "id": "Q24400-1", "name": "Muscle LIM protein Mlp84B", "aln": "----------------MPSFQPIEAPKCPRCGKSVYAAEERLAG-----GYVFHKNCFKCGMCNKSLDS----------------------------------------------------------------TNCTEHERELYCKTCHGRKFGP--KGYGFGTGAGTLSMDNGSQFLRENGDVPSVRNGARLEPRAIARAPEGEGCPRCGGYVYAAEQMLARGRSWHKECFKCGTCKKGLDSILCCEAPDKNIYCKGCYAKKFGPKGYGYGQGGGALQSDCYAHDDGAPQIRAAIDVDKIQARPGEGCPRCGGVVYAAEQKLSKGREWHKKCFNCKDCHKTLDSINASDGPDRDVYCRTCYGKKWGPHGYGFACGSGFLQTDGLTEDQISANRPFYNPDTTSIKARDGEGCPRCGGAVFAAEQQLSKGKVWHKKCYNCADCHRPLDSVLACDGPDGDIHCRACYGK------LFGPKGFGYGHAPTLVSTSGESTIQFPDGRPLAGPKTSGGCPRCGFAVFAAEQMISKTRI-WHKRCFYCSDCRKSLDSTNLNDG----PDGDIYCRACYGRN-FGPKGVGYGLGAGALTTF----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P35688-1", "uniprot_id": "LRG1_YEAST", "id": "P35688-1", "name": "Rho-GTPase-activating protein LRG1", "aln": "MIQNSAGYRSLNTASPMTVQVKNQKKICARCNKLVIPDSQRTKTTLKALGKYYHESCFTCQDCQKPLKPKYFPYQVDKTSESILLCQYDYFRRHNLLCHVCDTPLRGLYYTAFGYRYDEEHFSCTICATPCGVKKCFMYGNQLYCKYHFLKYFSKRCKGCEFPISDQYIEFPKGEEIHCWHPECYG---------------------------------------------------------------------------------------------IHKYWHVNLAAETVGLQYLPKLEYNPNSGDKDINPTAYELDKQMQAFNFILSKTWSVLYRFEEEAASCISDMFQYLTSNDQLKG----IESTGLLVLKIDCLFRGLDTLNLSTNKSMPVNSDQECIENNAMAASKYSKFPKNLSTKIMIYLQLLRKLGTENKNETITISSFMSVITGLAHFLKLLTRFGLYTALENNKLTHSVNPLLRFLREVEKNELFENNPFQYIKTPVNATDSCAGCNKYIQEECIQFYEHRWHIACFTCSSCHKNINPRSLTDPTFNKEKKKILCSHCSIDDPASVPGFKFVTKLAQLIFLLKIALVKSRTVMLKSKASNKVGRNSLQSTMLKEQTYIRTLNDIKRLRSRRESVRVTHNKQQARKSVILETAETDLNDPTKQGDSKNLVIQTDDPSSSQQVSTRENVFSNTKTLTLDDISRIVAAEQARELRPNAFAHFKKLKETDDETSNVVPKKSGVYYSELSTMELSMIRAISLSLLAGKQLISKTDPNYTSLVSMVFSNEKQVTGSFWNRMKIMMSMEPKKPITKTVFGAPLDVLCEKWGVDSDLGVGPVKIRIPIIIDELISSLRQMDMSVEGIFRKNGNIRRLRELTANIDSNPTEAPDFSKENAIQLSALLKKFIRELPQPILSTDLYELWIKAAKIDLEDEKQRVILLIYSLLPTYNRNLLEALLSFLHWTSSFSYIENEMGSKMDIHNLSTVITPNILYLRHKEISNDNVPDEPESGLVDSFAQNKGENYFLAIEIVDYLITHNEEMAMVPKFLMNLLKDVQLQKLDNYESINHFISTVMQSKTIDYSECDIKTPVTVKDSTTTVIQGEINK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. * *.: * .: * :*. ** * *.* *.. .. : .::*** . : :. ** : . :.: .* :: .* . ..::. . . . . .. : . .* : *: * . ** ** *:.* *.::. .*.: . .* * * : . *. : . * ", "identical_positions": 35, "similar_positions": 63, "identity": "3.14%" }, { "cls_id": "homologset.agr.MGI:1203290", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P15529-1", "uniprot_id": "MCP_HUMAN", "id": "P15529-1", "name": "Membrane cofactor protein", "aln": "--------------------------------------------------------------------------------------------------------------------------------MEPPGRRECPFPSWRFPGLLLAAMVLLLYSFSDACEEPPTFEAMELIG------------KPKPYYEIGERVDYKCKK-----------------------------------------------------------------------------------------GYFYIPPLATHTICDRNHTWLPVSDDACYR-----------------------------------------------------ETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKG-SVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAP-GPDPFSLIGESTIYCGDNS----VWSRAAPECKVV-KCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVLPP---------------------SSTKPPALSHSVSTSSTTKSPASSASGPRPTY--KPPVSN---------YPGYPK------------------------------------------------------------------------------------------------------------------------------PEEGIL-DSLDVWVIAVIVIAIVVGVA--------------VICVVPYRYLQRRKKK-----------GTYLTDETHREVKFTSL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O88174-1", "uniprot_id": "MCP_MOUSE", "id": "O88174-1", "name": "Membrane cofactor protein", "aln": "----------------------------------------------------------------------------------------------------------------------MTAAPLMPDSTHPCRRRKSYTFFWCSLGVYAEALLFLLSHLSDACELPRPFEAMELKG------------TPKLFYAVGEKIEYKCKK-----------------------------------------------------------------------------------------GYLYLSPYLMIATCEPNHTWVPISDAGCIK-----------------------------------------------------VQCTMLQDPSFGKVYYIDGSFSWGARAKFTCMEGYYVVGMSVLHCVLKGDDEAYWNGYPPHCEKIYCLPPPKIKNGTHTLTDINVFKYHEAVSYSCDPTP-GPDKFSLVGTSMIFCAGHN----TWSNSPPECKVV-KCPNPVLQNGRLISGAGEIFSYQSTVMFECLQGFYMEGSSMVICSANNSWEPSIPKCLK---------------------------------------------------GPRPTHPTKPPVYN---------YTGYPS------------------------------------------------------------------------------------------------------------------------------PREGIFSQELDAWIIALIVITSIVGVF--------------ILCLIVLRCFEHRKKT-----------NVSAAR----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63135-1", "uniprot_id": "CR1L_RAT", "id": "Q63135-1", "name": "Complement component receptor 1-like protein", "aln": "-----------------------------------------------------------------------------------------------------------------------------MEASSPLDPVGRLVAFCRGGVHLAVLLLFLSPSTLGQCPAPPLFPYAKPINP-----------TDESTFPVGTSLKYECRP-----------------------------------------------------------------------------------------GYIKR---QFSITCEVNSVWTSP-QDVCIR-----------------------------------------------------KQCETPLDPQNG-IVHVNTDIRFGSSITYTCNEGYRLIGSSSAMCIISD-QSVAWDAEAPICESIPCEIPPSIPNGDFFSPNREDFHYGMVVTYQCNTDARGKKLFNLVGEPSIHCTSIDGQVGVWSGPPPQCIELNKCTPPHVENAVIVSKNKSLFSLRDMVEFRCQDGFMMKGDSSVYCRSLNRWEPQLPSCFKVKSCGA--FLGELPNGHVFVPQNLQLGAKVTFVCNTGYQLKGNSSSHCVLDGVESIWNSSVPVCEQVICKLPQDMSGFQKGLQMKKDYYYGDNVALECEDGYTLEGSSQSQCQSDASWDPPLPKCVSQVICKLPQDMSGFQKGLQMKK-------------------------DYYYGDNVALECEDGYTLEGSSQSQCQSDASWDPPLPKCVSRSNSGLIAGIFIGIIVLIL--------------FIIFSYWMIMKFKKRNSTNEKCKE--VGIYLNSKEDSCVQPQSLLTSQENNSTSSPARN--------------SLTQEV------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0AC58JVW1-1", "uniprot_id": "A0AC58JVW1_DANRE", "id": "A0AC58JVW1-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------MTSVRTLLLLFLSSLLVTMGKAKCLFPVLNGNHVLSLES------------RLKNEFPDGSTAVAECAR-----------------------------------------------------------------------------------------GYEAKDG-SPLITCQ-NGKWSKV-ELKCEK-----------------------------------------------------MDCGPPEPQSSHMTYLINNGTLFGAYVKALCDTGYDLEGSSYRQCLVTG-----WNGR-ATCTLITCDNPTPPEHGNVMFR--SPVLYNDVIKYSC------QENYTLVGNRSLTCGDDWD----YNFPPPKCEAI-ECGVPTIKFGNQTEG-NPPYLHKSQATFECLPGYRMNGSATSVCEE-RGWS-ALPECVKATPTP-----------VSHSSVKMSISITPCDVITFAANRNGSSKFERDANGDAHSACSVLPAFSLPFMSILLQPEETTTVVASTVTTDIATTNAVFCKE-------------------------------------------------------------------------------------------------EEEEEEEEEEHFITVSQNNSVWIIVVAVLATLAIVC--------------ILCGLLHYNYKHKGWLMLQWRSRINMLSVSGKSAPHIYIFISSAMWMASGPALSIYRCK--------------GLCSAVGAKTGLKKILWKWKALTGGRSFVFSAQDPQPSPLGDRPIGNLQGTRDQRRLVHL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A8JUX3-1", "uniprot_id": "A8JUX3_DROME", "id": "A8JUX3-1", "name": "Furrowed", "aln": "MHRTQPSLPLPLPLLALALALASALAFAQAQNIDAGCSFPGSPAHSSVVFSNANLTQGTVASYSCERGFELLGPARRVCDKGQWVPEGIPFCVLNVAAGKAPMQISTDGAGAPQKAIDGSTSAFFTPETCSLTKAERSPWWYVNLLEPYMVQLVRLDFGKSCCGNKPATIVVRVGNNRPDLGTNPICNRFTGLLEAGQPLFLPCNPPMPGAFVSVHLENSTPNPLSICEAFVYTDQALPIERCPTFRDQPPGALASYNGKCYIFYNRQPLNFLDALSFCRSRGGTLISESNPALQGFISWELWRRHRSDVSSQYWMGAVRDGSDRSSWKWVNGDELTVSFWSHPGGDEDCARFDGSKGWLWSDTNCNTLLNFICQHQPKTCGRPEQPPNSTMVALN-GFEVGAQIKYSCDANHLLVGPATRTCLETG----FYNEFPPVCKYIECGLPASIAHGSYALLN-NTVGYLSLVKYSC------EEGYEMIGRALLTCDFDER----WNGPPPRCEIV-ECDTLPGNYYSTIINAPNGTYYGSKAEISCPPGYRMEGPRVLTCLASGQWSSALPRCIKLEPSTQPTAASTIPVPSSVATPPPFRPKVVSSTTSRTPYRPAVSTASSGIGGSSTSTVGTYPSLSPTQVEINGESESEEEINVPPVPGTVREEFPPRRTVRPVLIPKKPNSTPAALPPTTHQVPPQPPSTYAPTPPRSSRPSGAPNSAGEVETTTRNTQQIIANSHPQDNEIPDSVNIQQNQSPNVNVPFAVDNPDRKETKEAKLNLGAIVALGAFGGFVFLAAVITTIVILVRSTPNSQRRHLAKHLTAYQHHHAHHHHHQQIQQQFHHRNQQQQQQEQHHQNHTRQQQQKYHQQQEQLHQSHRQKKQPSQSKKGQGGIGIGIGIGIPRPSRLPSYATATATSATSYASTAQLTQSHLFPDGGGYGSVGSSSAGGLVHAPSMWYSVLALPFDDQKLGRREFSSYGRGYRARAGLFSNSHINRTTQHYRHRASPDCNTVASFDSSTSGSRNGLNRYYRQAWENLHESASKNSSHNALRRKETLDPPSMTRSRDNLRDNMQRSRENLDRCGRDNYGMRDDSEMVVSSVVSDVCLKGEKKRHHHHHHKSSSRNGDYRDRDHSSGRREHHRHSGGGGGGGGGGGGHY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. . * * *: . * . : * : * * .: : * * .. :. . * : * *. :* . . * :.*.* . : ::* : * :. ..*.* : :* : . : * *: :.* * *. :* *.* * * . . :: .: :. : . . : ", "identical_positions": 31, "similar_positions": 57, "identity": "2.68%" }, { "cls_id": "homologset.agr.MGI:1203481", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9Q3S4-1", "uniprot_id": "M3K19_MOUSE", "id": "E9Q3S4-1", "name": "Mitogen-activated protein kinase kinase kinase 19", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDSMPRPERHAESLLDICHEAGSTPME-MTVSQTENLTLQSISSS--EDFDLEDDFSPFILAREGAAPRG--ENWPRRTEGVEIIVT-FPPDP--LQEASQEDLKESNQVTSEHQEREQVHPVSPPDDAEMVGLTGRMLTTQPSLLKTDGSSEELCGVDVALSPPRPCLDSSLAASAAGEVAPCVLKEQQRQSDEFPTSDISYSSRRTGLPLPPLSCLPMRSCIFNMEKSPKSPRHRERKVPSLSLSVPKLLEPLSRPLSQSAEFSSSKNHQEVTQEGPVEHTLRGSNCTLWSRNMCSFRKSGKQ-GVAES---WPSQEMEGWDKTKTSGFKEGPSLFSCESVKEDTTPTERERDSGYHVSEMQR-GGEDSQYLSSRKKESWTARVVERDSGVEHPILCKLLEVSNSEMTPAEEKEIGNENVPDAKSNSVHKSGAMEPHAASEEVSVPKNGPSVNSDGPAE-ELEGHRDIEQNRKIPMEEETNPEMNGVVPLTHIAFPGEGTSKGPARAEPHLQRRKRPAQNSNSFNLLAHREHDKLQTNTHRTKLDSRTKARNRAPPNLMVSIQASIKPNMHKNSIKTQVFPALELIDHRPHPSSKFQRRAPLTEKK-STHQTQKPKKQAFPRIGKHAGIKKPGIPLSAETTDPRLHFLDLKYSDMFKEINSASNGPGIYEMFGTPVYCHIREAERHDHRCYREIRTAPSGRCVVNKCQSSESDRCSNSRARLLQKRQHIKPPKPLHGLRQKHRGFISKDKGCKDMGG-----HTEDSVSEPDGQMKSPGNDFLSSKDDAQLMHLIPIPELSPEQKAPAPVSDLSIVEEIFTEECADEEGILNDDSLTQSLGDLKEPEGLHPQAPLVPSENSWAVLSEKRSGKRVSPEKHNVEPLDKINAEQMFPGYLEFDSLSEKSKTLVSFSSCSFQENLERAPSPTEQHWARSLEQDSLENNSTTYQTFGK-------ISQEILDPGKNEELTDELLGCLVEELLALDEKDNNSCQIMTNEADAKNLNLVFSRRGNTIEELGRETTDVKLQRCINGFRIYD-EENFLTSNEKKTLSDKSLNHEEAIFWTKGEILGRGAYGTVYCGLTSLGQLIAVKQVALDTSDKLATEKEYRKLQEEVDLLKALKHVNIVAYLGTCLEENTLSIFMEFVPGGSISSIINRFGPLPEMVFCKYTRQILQGVAYLHDNCVVHRDIKGNNVMLMPTGIIKLIDFGCAKRLAWAGLNGTHSDMLKSMRGTPYWMAPEVINESGYGRKSDIWSIGCTVFEMATGKPPLASMDRMAAMFYIGAHRGLMPPLPARFSEPAADFVRLCLTRDQHERPSALQLLKHSFLKRSQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1LVM0-1", "uniprot_id": "F1LVM0_RAT", "id": "F1LVM0-1", "name": "Mitogen-activated protein kinase kinase kinase 19", "aln": "MNKNKLIHDFLEVVSRGDVECICSHIPEVHSVLGNLDFQHPQTGNTPLITAAEENLSEVVEILLERGADITLCNYSNQTALHVANGDIQRQLLAGRGIQAPQMQLLRSSWQGDLERLRHLLACEEFLDINFPNSHGLTPLMLAVRDVDLFESLDVSTVYRPAEVLAELLRHHADPKLCDFSGKSAMHYVSQINSWRKQQLLVILTDSMPKPERHAESLLDICHEAGSTPMD-MTVSKTENITLQSISSSSSEDFALDDDFSPSILAGEGTAPRG--EGWPRRTEGVEILVTMFPPDS--PQEASQEDLTESSQWG-------PGHPVSPAKEVEMVGLTSRMLTTQPSLLKTEGGSQELCGADVALSPPRPCLDPSTAIAAVREEAPHVLKVQPRKSDKFPTSDMRYSSRRTELPLPPPSLLPMRSSVFNMEKSPKFPRHGERKVPSLSLSVPKLLEPLSQPLSQSAEFSSAKNQQEVTWEGPPEHTLRGSDWAIWSRNLCSFRKSRKQRGVAES---WRSQETKGGDKTETSGFEEGPFLFSCGSVKEDTAPIERERDSGCHISEIS--GREDSQYLLSGEKESWTDRAVEKDLEVEHPFLSELLEASNTKITLAEEKEIGNEKVPDSESNSVHRAGTVQPHAVLEELSVPKNIPRMNSDGPITGLLEGHGDTEENRKLPIEEETNPEMNGAVPLVHITFPGEGTPKGPARAKPNLQRRKHPVQSSGSPNILARQEHGKLQTNTHR------TKARNRPPPNLMVSIQASIKPNVRKNSIKTQVFPALEFMDHRPHPPSKFQRRAPVTEKK-SMCQTQKPKKQAFPHICKNAGIKKPGVVLSVETTDPRLHFLDLKYSDMFKEINSASNGPGIYEMFGTPVYSHIREAERHEHRHYHEICAAPSGRSVGNKCQPSQSDRCANSRARLLQKRPHVKPPKPSLGLKQKHRGLISKDKGCKGMGG-----HVEDSVSEPGWQTRPSANDSLSSKDEAQLTHLTLIPETSPEQRETPPLSDLSIVEEIFTEECADEEGILHNDSLTQSLGDLKALEGLHPQTPLVPSEDSWAVLSEKHSGKHVSPGKHDVGPLDKINADQMFTGYLEFDSLSDKSKTRVSFSRYSFQEKPESAPSPTEQPWAHSLDQDSLEDDSTTYQRFGK-------VSQGILDPGKNEELTDELLGCLVEELLAIDEKDNNSCRIMTNEADTRDLNLVFGRRGNTIEGLDRETTDVKLQRCINGFQIYD-EENFLTSYEERTLSDNSLKHEEAIFWTKGEILGRGAYGTVYCGLTSLGQLIAVKQVALDSTDKLATEKEYRKLQEEVDLLKALKHVNIVAYLGTCLEENTLSIFMEFVPGGSISSIINRFGPLPETVFCKYTRQILQGVAYLHENCVVHRDIKGNNVMLMPTGIIKLIDFGCAKRLAWAGLNGTHSDMLKSMRGTPYWMAPEVINESGYGRKSDIWSIGCTVFEMATGKPPLASMDRMAAMFYIGAHRGLMPPLPDRFSEPAADFVRLCLTRDQHERPSALQLLTHAFMLRSQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q56UN5-1", "uniprot_id": "M3K19_HUMAN", "id": "Q56UN5-1", "name": "Mitogen-activated protein kinase kinase kinase 19", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSMPKPERHAESLLDICHDTNSSPTDLMTVTKNQNIILQSISRS--EEFDQDGDCSHSTLVNEEEDPSGGRQDWQPRTEGVEITVT-FPRDVSPPQEMSQEDLKEKNLINSSLQEWAQAHAVSHPNEIETVELRKKKLTMRPLVLQKEESSRELCNVNLGFLLPRSCLELNISKSVTREDAPHFLKEQQRKSEEFSTSHMKYSGRSIKFLLPPLSLLPTRSGVLTIPQNHKFPKEKERNIPSLTSFVPK----LSVSVRQSDELSPSNEPPGALVKSLMDPTLRSSDGFIWSRNMCSFPKTNHHRQCLEKEENWKSKEIEECNKIEITHFEKGQSLVSFENLKEGNIPAVREEDIDCHGSKTRKPEEENSQYLSSRKNESSVAKNYEQDPEIVCTIPSKFQETQHSEITPSQDEEMRN-NKAASKRVSLHKNEAMEPNNILEECTVLKSLSSVVFDDPIDKLPEGCSSMETNIKISIAERAKPEMSRMVPLIHITFPVDGSPKEPVIAKPSLQTRKGTIHNNHSVNIPVHQENDKHKMNSHRSKLDSKTKTSKKTPQNFVISTEGPIKPTMHKTSIKTQIFPALGLVDPRPWQLPRFQKKMPQIAKKQSTHRTQKPKKQSFPCICKNPGTQKSCVPLSVQPTEPRLNYLDLKYSDMFKEINSTANGPGIYEMFGTPVYCHVRETERDENTYYREICSAPSGRRITNKCRSSHSERKSNIRTRLSQKKTHMKCPKTSFGIKQEHKVLISKEKSSKAVHSNLHDIENGDGISEPDWQIKSSGNEFLSSKDEIHPMNLAQTPEQSMKQNEFPPVSDLSIVEEVSMEESTGDRDISNNQILTTSLRDLQELEELHHQIPFIPSEDSWAVPSEKNSNKYVQQEKQNTASLSKVNASRILTNDLEFDSVSDHSKTLTNFS---FQAKQESASSQTYQYWVHYLDHDSLANKSITYQMFGKTLSGTNSISQEIMDSVNNEELTDELLGCLAAELLALDEKDNNSCQKMANETDPENLNLVLRWRGSTPKEMGRETTKVKIQRHSSGLRIYDREEKFLISNEKKIFSENSLKSEEPILWTKGEILGKGAYGTVYCGLTSQGQLIAVKQVALDTSNKLAAEKEYRKLQEEVDLLKALKHVNIVAYLGTCLQENTVSIFMEFVPGGSISSIINRFGPLPEMVFCKYTKQILQGVAYLHENCVVHRDIKGNNVMLMPTGIIKLIDFGCARRLAWAGLNGTHSDMLKSMHGTPYWMAPEVINESGYGRKSDIWSIGCTVFEMATGKPPLASMDRMAAMFYIGAHRGLMPPLPDHFSENAADFVRMCLTRDQHERPSALQLLKHSFLERSH", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .***:*************::.*:* : ***::.:*: ***** * *:* :.* * *. * * * :.* ******* ** ** * ** *****.*.. *.** ..: * * * : ** :* :*:.: .*.***..::.: **.**: . : :.. * ** .** * *:*::*.**.: **.* : *** * ** ** ::.: :. * *:. **::***: *** ** .: ** *:*.::: . :. : ***.*: :****:*** *: :: *. * *:* : :* : : *::* *.* .:**.. * **.* . * *: *:**** * ::** . : *:* : .: .:: *..::::* ::::*: * : . :: *:*: :::*: ** :* *. . : *.* ** . * * *:.: *.::***. *** **:** :*:.* *. *:* ** ** . :.. * *: .::*:.* : *:** **: ::.* *:::* :..***.::*.*****:**** ::* ** .:**:: * ** * :*******:** * *:.* :*. : **.:.*:***::**************::**************.*:**:**.:: *:** :***** : ***:.*.*:* :* *:** **: *:* **. *::*:*: :***:*..* : . . *.:***. * :...*: *****: : :* ** * :*. .*:********: **.:.:..* ::: ** ** **: * ** * *::***:**** ***.*.* *. *::. .*.*:**.:::.. *****:*::*** ..** ** : * *.* * * *.: *::*** :.* *** *** :** *:*. :************. ****:********: *:**:*..:****: **.* : :.****.**:** .*::*** **:** * *:: :*::**: **.*:********:************ ************:::***:******************************:***:************************ ******:**********:*****************************:******************:************************************************************** :*** ******:****************.*:*: **:", "identical_positions": 704, "similar_positions": 334, "identity": "45.63%" }, { "cls_id": "homologset.agr.MGI:1203484", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LYF2-1", "uniprot_id": "A0ABK0LYF2_RAT", "id": "A0ABK0LYF2-1", "name": "", "aln": "------------MPGAGVPAAASSPKSGASGALQVSDSLRRFVLFLENFAPLVNSLSLGIANPLLLGPSPLHFAQIKTQLALQQLNAVA----SHGSTPPYTLLNQAFLKVAMSRPRFNPRG-TFP-LQRPRAPNPPGMRPP------GPFVRPGSMG-------LPRFYPAGRARGIPHRFPGHGSYQNMGPQRMNVQVT------QHRTDPRLTKEKLDFPEAQQKKGKPHGSRWD--DEPHITPPVEVKQSSVTQVTEQSPKVQSR---------------------YTKESASSILASFGLSNEDLEELSRYPDEQLTPENMPLILRDIRMRKMGRRLPNLPSHSRNKETLSNETVSSNVIDYGHASKYGYTEDPLEVRIYDPEIPTDEVKNEFQSQQSISATVSTPNVICNSVFPGEDVFRQMDFPGESSS-QSFFPVESGTKMSGLHISG-QSVLEPVKSISQSISQTVSQTTSQSLNRPSMNQPPFSSELISALSQQERIPQKSVISSADTHGGPRGSKKSYQTEADLPIRSPFGIVKASWLPKFT-QAGAQKMKRLPTPSMMNDYYAASPRIFPHLCSLCNVECSHLKDWIQHQNTSTHIESCRQLRQQYPDWNPEILPSRRNESNRKENETPRRR-----SHSPSPRHSRRSSSGHRVRRSRSPIRYIYRPRSRSPRICHRFISKYRSRSRSRSRSRSPYRSRNLIRR---SPKSYRSVSPERTSRRSVRS-DRKKALEDGGQRSIHGTEVTKQK-----HIEAVDKGLSPAQKPKLTSGTKPSAKSISSVKSDSHLGGHSA-HKSKNLEDDTLPEGKQVSGKGALVQRKPRKDQSLSSNSILLVSELPEDGFTEEDIRKAFQPFGKISDVLLVPCRNEAYLEMEFKKAVTSIMKYIETMPLVIKGKSVKVCVPGKKKPQNKEMK------------KKPLDLKKS-ASALKKETDASKVIENVTSA-SSAKSGQIKSSTVKVNKSAGKSAGSVKSVVTVAAKG-KASIKTAKSG-KKSLEAKKSGNIKNKD--------YNKPVTVSANSEVKASREDKATGKTAVETTS-GALEATENEPVSKEMEE---------------------------MSVVFISNLPNKGYSTEEIYNLAKPFGALKDILVLSSHKKAYIEINKKSADSMVKFYTCFPICMDGNQLSISMAPEDVDLKDEEALFTTLIQESDPEANIDEIYN--RFVHLDNLPEDGLQCVLCVGHQFGKVDRYVFMSNRNKVILQLESPESALSMYNFLKQNPQNIGDHVLSCTLSPKMDS-EVQKKNDPELGKE---SPDLKNSPVDESEVQTAADSPSVKPSEVEEETTSNIGTEPSVHQEELGKEEPKQALCESDFAIQTLELEAQGAEVSIEIP----LVASTPANIELFSENIDESALKQQMYASDFEKEEAEVTNLETELPGSDSVFIEERNIKG--ILEESPSETEDIFSGSAQPMVEAIAEVDKHETVSEVLPSACIVTQVQGGYE-DEKSVSKKDITEK-GSVDEKKEN-EFSTTGTRMDLQMKMEKAEESEANIFAEKLEKIIAAIREKPIESAVIKADPAKGVEQSSKPD------ETGKTSVLTVSSVYSSKSSIKATVVSSPKAKSTPSKTESQNIFPKPVLREQINAEKKVSAKEFGLLKNT--RSGLAESNSKSKPTQIGVNRGCSGRISALQCKDSKVDYKDITKQSQETETKPPIMKRDDSNNKALALQNTKNSKSTTDRSS--------------------KSKEEPLFTFNLDEFVTVDEVIEEVN-------------------------PSQAKQNPLKGKRKEALKISPSPELNLKKKKGKTSVPHSVEGELSFVTLDEIGEEEDST---AQALVTVDEVIDEEELNMEEMVKN---------SNSLLTLDELIDQDDCIP--------------------HSGPKDVTVLSMAEER-------DLQ-QERLVTVDEIGEVEES-----ADITFATLNAKRDK--------RDSIGFISSQMPEDPSTLVTVDEIQDDS--SDFHLMTLDEVTEEDE-----------------------------DSLADFNNLKEELNFVTVDEVGDEEDGDNDSKVELAQGKIDHRTDKKGTRKRRAVDPKKTK-------------------------------------LDPFSQVGPGSETVTQKDLKTMTERHLA------------------------------------VDEAELKD-----LEPDEKRRKIE----DSSIGKSVTSDVSGDLDFLVPKAGFFCPICSLFYS-GEKAMANHCKSTRHKQNTEKFMAKQRKEKEQNETEERSSR-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61464-1", "uniprot_id": "ZN638_MOUSE", "id": "Q61464-1", "name": "Zinc finger protein 638", "aln": "----------------------------------------------------------------------------------------------------------------MSRPRFNPRG-TFP-LQRPRAPNPPGMRPP------GPFVRPGSMG-------LPRFYPAGRARGIPHRFPGHGSYQNMGPQRMNVQVT------QHRTDPRLTKEKLDFPEAQQKKGKPHGSRWD--DESHITPPVEVKQSSVTQVTEQSPKVQSR---------------------YTKESASSILASFGLSNEDLEELSRYPDEQLTPENMPLILRDIRMRKMSRRLPNLPSHSRNKETLSNETVSSNVIDYGHASKYGYTEDPLEVRIYDPEIPTDEVKNEFQPQQSISATVSTPNVICNSVFPGGDMFRQMDFPGESSS-QSFFPVESGTKMSGLHISG-QSVLEPVKSISQSISQTVSQTTSQSLNPPSMNQVPFTFELDAVLRQQERISQKSVISSADAHGGPTESKKDYQSEADLPIRSPFGIVKASWLPKFT-QAGAQKMKRLPTPSMMNDYYAASPRIFPHLCSLCNVECSHLKDWIQHQNTSTHIESCRQLRQQYPDWNPEILPSRRNESNRKENETPRRR-----SHSPSPRHSRRSSSGHRIRRSRSPVRYIYRPRSRSPRICHRFISKYRSRSRSRSRSRSPYRSRNLLRR---SPKSYRSASPERTSRKSVRS-DRKKALEDGGQRSVHGTEVTKQK-----HTETVDKGLSPAQKPKLASGTKPSAKSLSSVKSDSHLGAYSA-HKSENLEDDTLPEGKQESGKSALAQRKPQKDQSLSSNSILLVSELPEDGFTEEDIRKAFLPFGKISDVLLVPCRNEAYLEMELRKAVTSIMKYIETMPLVIKGKSVKVCVPGKKKPQNKEMK------------KKPSDIKKSSASALKKETDASKTMETVSSS-SSAKSGQIKSSTVKVNKCAGKSAGSVKSVVTVAAKG-KASIKTAKSG-KKSLEAKKSGNIKNKD--------SNKPVTVPANSEIKASSEDKATGKSAEESPS-GTLEATEKEPVNKESEE---------------------------MSVVFISNLPNKGYSTEEIYNLAKPFGALKDILVLSSHKKAYIEINKKSADSMVKFYTCFPISMDGNQLSISMAPEHVDLKDEEALFTTLIQENDPEANIDKIYN--RFVHLDNLPEDGLQCVLCVGHQFGKVDRYMFMSNKNKVILQLESPESALSMYNFLKQNPQNIGEHVLTCTLSPKTDS-EVQRKNDLELGKGSTFSPDLKNSPVDESEVQTAADSSSVKPSEVEEETTSNIGTETSVHQEELGKEEPKQALCESDFAIQTLELEAQGAEVSIEIP----LVASTPANIELFSENIDESALNQQMYTSDFEKEEAEVTNPETELAVSDSVFIEERNIKG--IIEDSPSETEDIFSGIVQPMVDAIAEVDKHETVSEVLPSACNVTQAPGSYIEDEKVVSKKDIAEK-VILDEKEED-EFNVKETRMDLQVKTEKAEKNEAIIFKEKLEKIIAAIREKPIESSVIKADPTKGLDQTSKPD------ETGKSSVLTVSNVYSSKSSIKATVVSSPKAKSTPSKTESHSTFPKPVLREQIKADKKVSAKEFGLLKNT--RSGLAESNSKSKPTQIGVNRGCSGRISALQCKDSKVDYKDITKQSQETETKPPIMKRDDSNNKALALQNTKNSKSTTDRSS--------------------KSKEEPLFTFNLDEFVTVDEVIEEVN-------------------------PSQAKQNPLKGKRKEALKISPSPELNLKKKKGKTSVPHSVEGELSFVTLDEIGEEEDAT---VQALVTVDEVIDEEELNMEEMVKN---------SNSLLTLDELIDQDDCIP--------------------HSGPKDVTVLSMAEEQ-------DLQ-QERLVTVDEIGEVEES-----ADITFATLNAKRDK--------RDSIGFISSQMPEDPSTLVTVDEIQDDS--SDFHLMTLDEVTEEDE-----------------------------NSLADFNNLKEELNFVTVDEVGDEEDGDNDSKVELARGKIEHHTDKKGNRKRRAVDPKKSK-------------------------------------LDSFSQVGPGSETVTQKDLKTMPERHLAAKTPMKRVRLGKSSPSQ--KVAEPTKGEEAFQMSEGVDDAELKD-----SEPDEKRRKTQ----DSSVGKSMTSDVPGDLDFLVPKAGFFCPICSLFYS-GEKAMANHCKSTRHKQNTEKFMAKQRKEKEQNETEERSSR-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14966-1", "uniprot_id": "ZN638_HUMAN", "id": "Q14966-1", "name": "Zinc finger protein 638", "aln": "----------------------------------------------------------------------------------------------------------------MSRPRFNPRG-DFP-LQRPRAPNPSGMRPP------GPFMRPGSMG-------LPRFYPAGRARGIPHRFAGHESYQNMGPQRMNVQVT------QHRTDPRLTKEKLDFHEAQQKKGKPHGSRWD--DEPHISASVAVKQSSVTQVTEQSPKVQSR---------------------YTKESASSILASFGLSNEDLEELSRYPDEQLTPENMPLILRDIRMRKMGRRLPNLPSQSRNKETLGSEAVSSNVIDYGHASKYGYTEDPLEVRIYDPEIPTDEVENEFQSQQNISASVPNPNVICNSMFPVEDVFRQMDFPGESSNNRSFFSVESGTKMSGLHISGGQSVLEPIKSVNQSINQTVSQTMSQSLIPPSMNQQPFSSELISSVSQQERIPHEPVINSSNVHVGSRGSKKNYQSQADIPIRSPFGIVKASWLPKFS-HADAQKMKRLPTPSMMNDYYAASPRIFPHLCSLCNVECSHLKDWIQHQNTSTHIESCRQLRQQYPDWNPEILPSRRNEGNRKENETPRRR-----SHSPSPRRSRRSSSSHRFRRSRSPMHYMYRPRSRSPRICHRFISRYRSRSRSR----SPYRIRNPFRG---SPKCFRSVSPERMSRRSVRSSDRKKALEDVVQRSGHGTEFNKQK-----HLEAADKGHSPAQKPKTSSGTKPSVKPTSATKSDSNLGGHSIRCKSKNLEDDTLSECKQVSDKAVSLQRKLRKEQSLHYGSVLLITELPEDGCTEEDVRKLFQPFGKVNDVLIVPYRKEAYLEMEFKEAITAIMKYIETTPLTIKGKSVKICVPGKKKAQNKEVK------------KKTLESKKVSASTLKRDADASKAVEIVTST-SAAKTGQAKASVAKVNKSTGKSASSVKSVVTVAVKGNKASIKTAKSGGKKSLEAKKTGNVKNKD--------SNKPVTIPENSEIKTSIEVKATENCAKEAISDAALEATENEPLNKETEE---------------------------MCVMLVSNLPNKGYSVEEVYDLAKPFGGLKDILILSSHKKAYIEINRKAAESMVKFYTCFPVLMDGNQLSISMAPENMNIKDEEAIFITLVKENDPEANIDTIYD--RFVHLDNLPEDGLQCVLCVGLQFGKVDHHVFISNRNKAILQLDSPESAQSMYSFLKQNPQNIGDHMLTCSLSPKIDLPEVQIEHDPELEKE---SPGLKNSPIDESEVQTATDSPSVKPNELEEESTPSIQTETLVQQEEPCEEEAEKATCDSDFAVETLELETQGEEVKEEIP----LVASASVSIEQFTENAEECALNQQMFNSDLEKKGAEIINPKTALLPSDSVFAEERNLKG--ILEESPSEAEDFISGITQTMVEAVAEVEKNETVSEILPSTCIVTLVPGIPTGDEKTVDKKNISEKKGNMDEKEEK-EFNTKETRMDLQIGTEKAEKNEGRMDAEKVEK-MAAMKEKPAENTLFKAYPNKGVGQANKPD------ETSKTSILAVSDVSSSKPSIKAVIVSSPKAKATVSKTENQKSFPKSVPRDQINAEKKLSAKEFGLLKPTSARSGLAESSSKFKPTQSSLTRGGSGRISALQGKLSKLDYRDITKQSQETEARPSIMKRDDSNNKTLAEQNTKNPKSTTGRSS--------------------KSKEEPLFPFNLDEFVTVDEVIEEVN-------------------------PSQAKQNPLKGKRKETLKNVPFSELNLKKKKGKTSTPRGVEGELSFVTLDEIGEEEDAAAHLAQALVTVDEVIDEEELNMEEMVKN---------SNSLFTLDELIDQDDCIS--------------------HSEPKDVTVLSVAEEQ-------DLLKQERLVTVDEIGEVEELPLNESADITFATLNTKGNEGDTV----RDSIGFISSQVPEDPSTLVTVDEIQDDS--SDLHLVTLDEVTEEDE-----------------------------DSLADFNNLKEELNFVTVDEVGEEEDGDNDLKVELAQSKNDHPTDKKGNRKKRAVDTKKTK-------------------------------------LESLSQVGPVNENVMEEDLKTMIERHLTAKTPTKRVRIGKTLPSEKAVVTEPAKGEEAFQMSEVDEESGLKD-----SEPERKRKKTE----DSSSGKSVASDVPEELDFLVPKAGFFCPICSLFYS-GEKAMTNHCKSTRHKQNTEKFMAKQRKEKEQNEAEERSSR-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58G3M4-1", "uniprot_id": "A0AC58G3M4_DANRE", "id": "A0AC58G3M4-1", "name": "", "aln": "MIKSNKNINSQDSAKNAITRSNVSKQANSMAIFPQPNATNSFSLFLESCVHPVPNSVRHFGNLPILSPVSLQLAQIKTQLALHQLNAIVGTSVTPAAVPTAALTLLNLLKVTMSHPLYNPRGGPFPSGQRPIVPSQYGLVSQPRMEMGAARLGPGTMSGSRAGLLGSSPFSMGQGQSQISTEIEAAIDRNLRGAREEVRIISQMLQQPKKADPRLRNDSMDEVLSSRGSGFSGSSRSDEVDWSMYQAPSKLFSSSMERPSSSSPVFKSAGFGGGPSGLSSQRPPEQRPNRYTSESATSILASFGLSNEDLELLSHYPDDQLTPDNLPFILRDIRMRKVKRDVDERPDYN-------------KVIDYGHSRKFDYPEESSES---------------YATEHLPKETPKYASKVSRPAFTASNITKQPQMCQSGPG---------PIHVSELHKPS----------------PVDPRPTKTIPARPPASQPALTPSSRPPLQVPSQLGVLPMMSVDDMPGGP------------------------NWIPFLSPPVSMPPMKRLPTPTMMNDYSAATPRIFPHTCSLCNIECVQIKDWLEHQNTNVHIENCRRLRKQYPDWKVESVPVSRSESKSEHSSSKRHARSHSYSRSPSPKRHHESSSRRKRSRSRTRSRSRSRSRSRSRSRSRSRGSRRYRRSRSRTRSPHRKSRSSPYRRRSRSPPSQRARSPGYSRRSPRRSSPRRSSPSRQQRSSSSELLAMKLMSSPELSSIADSDTLKAMVKSLAPALLAELAKKKSSSTVSSSKGSSSSSRRSPPPKKTEYSSTSRTSTSKSHSTSKPNPKYAPGTSCLLRLLGLP-IGTTSKDLTDAIEPFGKIYTAILLKAIREASVCMEREEDARALLNCKN---LTIHGQVIKVCMEKDAETGRKYIKPEKVFKKKEATITKPIQIPKGKAANVVKVPQPAKAKEVTGFKPTQATKGKPTEMKKTVPAAKPKPPAKVPAETAVAKKVVKKEIPWRKNIVEITNLPEAGVTEEELTNLAKPYGFTETPVIAITQQRAYLQMPNTEAAEKMVKTFSETPAKVKEKEITVKMMMQPIDLNYTESVFRVLMGMEKSPEIMTLPERLLIVGNVPKALGPVKEVETVVKRYGIFKKVLHLN-GRVIFEMENAASARAIFIRFVKFRCTLQDKVLSFQLAKPLKLKKKPDAKGAKPPAKPPAKPNTVKVQKPVAAAPAESAVKKDEKPSAAAKTVAPKEEDSIVISDNEVILIESDDEEKLKAKTTAAKLTEATKDSAVANANTAASENKVELNTQDTKESITVTPDAGSVKKELEAESSVTKVEPETIKKELEVESSASTSESAAESVNKELEVTETTVSVESGNADCHVESAVPASESAISVESVNGEHKEGSPASAIESGKADLEVKSASESAVLVESAKAEHELVSPESAIPVETTEQSEADSKKDQDVPQAEDAPKEPLSTSVEGKIEDEKLAEDREMELGTSGVSSEEMAVEPMETQSTEETAKDTDVKEDDCKPQEHIIDSEGQSKELTPTENVGADINPTTKAGANADASDSIPTSDPTSDLPSTSNQAFSNSTVPVTCASESPHVVPEPFLVNDQSLDFPPVTQEILKALELAVHQCRLQSSLKRAEEEAKQKAETEKKAAEKKTTKGQSGSKKPAQSTKKATPAQAKKMQAEKEKKSQSSGSKGKTTDTSSPEKESSSRYRTRGNSDEEGTTRRRGGSSGGSSLRSRRESSPPSKRTRGHDVDSRRPSRTHSRTRASVKEKEDESFSFNFDEFVTVDEVGDDAEDIVASTAESSAMDENIKDEPDPHTLTAQSEADKPKPTDSVVPSETSNSEINACVEELEAKAEETTQVDVDIAEEQESPEDSSDKPLETDIQCKTEKPCTVTETSSAETNTNDESLSAIKETSGIETLDELEPSHAVSSTQKEGSPPRSAETPEKLEDDHSEQPENSAPEMENKKEAADQTPELPCHDSLVTLDEVSEGEEDFIYETNEEQLLKADELPETLLTVDEVGDDETGIEEYQLEKDLQGLVTLDEVVDEEEFDPETLVTLDEAKGDDEELEQSESMPTSPRTTTPIIPEEPVKSPRQEDDASYLEELRKMNFVTVDEVGEEEEEEQPPCEEVKEEKPVKKRATRGRKRARQTPVRRSTRGKRGSAKVVEEPEEEEEPEATAEPEPVPEATIVESPPAAVESVALDVQPEQQKAEDMMVTDSLTAEVSEEDMIKSKDDVGSTKSETDTPDTADSNKKPTIKEESKERREIDPVEEPEAKRSRSQSPLIEDFTMPPFNPDNPIGIDFVIPRTGFFCKLCSLFYVNEDTAKKSHCSSLKHYQNMEKYYKKQKSQQQQGGSSSQSAASQGSASE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **:* :**** ** *** .*. *: . .. : **:*. . :. *:.:. :*: * :*:: :::**** ::.:* :.: .* . .** * * . .. : .**: : :..** .:* **.***:************** **:***:****:*:*:*********: * : : *. . :******: *:.*.*:. * : .:: . : .. :... *. :: :* :: .... ::* ** .. . .:. . *. .* .:: . . : .:: .::. : *. .*:* :: .. *******:***** **:****** *****:** ::***::****..***.**:**:*****: * :* *.*.: :...: *: *:****:: :.*** :: ***: : *.**** .: *: ***** . * ** . *: ** * . ** *:.: . : * * : .. .. *. .: .* *: . .* *. * :* :. .. .: * . * . . : ..:* : ** * *.:*: . : ****: .::: .** : ** .: :::: : *.*:*: :*:*: . :. .* :* .*. : * *: : : .:.:*. * . : *..*: . .* . *....* : .:** * * .* *. : : .: . :: :.** :.. . . : : :: * . :..*:* * : ::::.*:*: ..:*: :.* :* :*.:* *. : : * :* ::. :. * ::.: **:.:* *. :* . : .:.* : . . :. :.. : .. * : :.:*:.: ::: :. *. : . * . . .. : ... :.. : *:: :. * . : .:*:. **.* .. .. * *:*..::.. : *::* * . .. . . . : :. :. * .*.. ** . : : : .:. : * *: . :: : . : * . *. : : . : * : :. : : ::. :. *: :: *: ....:: *. :*: . * . . :: : .:. : :. :: . .: :* . . : : .: *. . ::. :: :** :: :.: * .. .. : . :: *:** : : * * : . : :.:* :: . ** . . * . . ::: .. . :* .... : :. ::....: *: *.**: *.**:********* ::.: .:*:: : * . . . . . .*:* :: ::.. . .: ::.:. :* *:.. .: ..:: * . * .* :..: ***** .. . ** : :. .: ::: :* :: ***:**:.* ** : : . : : *. *: . *: :* . ***:**: *:. . *:****.. :** :. *.: : .::*********:**: :: *: . * : .:* :: * . :::. ....*. : :: . * *: ::: : **: ** : : :. .. .* . :**::*::**** :***** :.* .**.* :* ** **: **:.:::*. :..:*: ", "identical_positions": 403, "similar_positions": 677, "identity": "16.87%" }, { "cls_id": "homologset.agr.MGI:1203495", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZTX4-1", "uniprot_id": "D3ZTX4_RAT", "id": "D3ZTX4-1", "name": "Sucrase-isomaltase, intestinal", "aln": "MARRRFKKFSTLELVLIVLLLILFIVAVVLIVLLANSTEPN-------------------------AVDAETTGTPDTTLTRTTLNFPECPVLSEAERINCIPDQSSNKDTCDQRGCCWDPQGSISVP-CYFSRNHGYKMESDLANTTAGFTAALKNLASAPVFGNGIENILLTAEYQTSNRFHFKLTDQTKERYEVPHEHVKPFSGNAASSLNYNVEVFKEPFSIKVTRKSNNRVLFDSSIGPLLFSDQFLQLSTHLPSANVYGLGEHVHQQYRHDMNWKTWPMFARDTTPNEDGNNLYGVQTFFLCLEDNSGLSFGVFLMNSNAMEVTLQPTPAITYRITGGILDFYVFLGNTPEQVVQEYLELIGRPTLPSYWTLGFQLSRYDYGSLDKMKIVVERNRAAQLPYDVQHADIDYMDQRKDFTYDPVNFKGFPEFVKELHNNGQKLVIILDPAISNNSLSSNPYGPYDRGSAMKVWVNSSDGN-ALIGKVWPGTTVFPDYTSPNCAVWWKKEIELFHNEVEFDGIWIDMNEVSNFVDGSVSGCSQNNLNYPPFTPKVLDGNLFSKTLCMDAVQHWGKQYDVHNLYGYSMAIATEEAVKTVFPDKRSFILTRSTFAGSGKFAAHWLGDNTATWKDLQWSIPGMLEFNLFGIPMVGADICGFAMNTYEELCRRWMQLGAFYPFSRNHNGQGYKDQDPASFGEDSLLLNSSRHYLNIRYTLLPYLYTLFYRAHSRGDTVARPLLHEFYEDSNTWDIDRQFLWGPGLLITPVLDQGAEKVKAYVPDATWYDYETGEQLAWRKQSVEMELPEDKIGLHLRGGYIFPTQQPATTTEASRKNPLGLIIALDKNKEAKGELFWDDGQTKDTVAKNLYLFTEFSATQNRLDVTISSPNYKDPNNLEFQEIKIFGTQEFRNVKVKQNGVLLQMSPQVNYNSNLKVATITNIHLMLGEAYTVEWDIFTRDEEKIDCYPDEHGVSEANCIARGCIWEVSNTPGVPHCYFANELYSVSNIQYNSHGATADIFLKASTYSNAFPSTPVNQLQLKVAYHKDQMLQFKIYDPNRSRYEVPVPLNIPSAPSSTPEGRLYDVFIKENPFGIQIRRKSTGTVIWDSQLLGFTFNDMFIRISTRLPSTYIYGFGETEHTTFKIDMNWQTWGMFSRDEPPGYKKNSYGVHPYYMGLEEDGNAHGVLLMNSNAMDVTFQPMPALTYRTVGGILDFYVFLGPTPEIVTEQYTELIGRPVMVPYWSLGFQLCRYGYENDTEIANLYDEMVAKRIPYDVQYSDIDYMERQLDFKLNPKFSGFPDLINRMKDNGMRVILILDPAISGNETEPYPAFTRGVENDVFISYPNNGGIVWGKVWPDYPNITVDPSLDWDSQVQQYRAYVAFPDFFRDSTALWWKNEIKELHSNSQDPAKSLKFDGLWIDMNEPSSFVNGAVPSGCTDTTLNRPPYMPHLEARDRGLSSKTLCMESEHILPDGSRVRHYDVHSLYGWSQTRPTYEAMQEVTGERGIVITRSTFPSSGRWGGHWLGDNTAAWDQLGKSIIGMMDFSLFGISYTGSDICGFFQDAEYEMCVRWMQLGAFYPFSRNHNTIGTKRQDPVSWNETFEDISRSVLETRYTLLPYLYTLMYKAHKEGSTVVRPLLHEFLADRETWNVDKQFLLGPAFLVSPVLELNARNVTAYFPKAQWYDYYTGADINSTGEWRTLPAPLEHINLHVRGGYILPWQQPALNTNLSRKKPLGLLIALNENKEARGELFWDDGQSKDTVAKNIYLFSEFSVTQNRLDVTISSPNYKDPNNLEFQEIKIFGTQEIRNVKVKQNGVLLQMSPQVNYNSNLKVATITNIHLVLGEAYTVEWDIYSKDVERIDCYPDEHGVSEANCTARGCIWEVSNTPGVPHCYFANELYSVSNIQYDSHGATADISLKASPYSNAFPSTPVNQLQLKVTYHKDQMLQFKIYDPNRSRYEVPVPLNIPSAPSSTPEGRLYDVFIKENPFGIQIRRNSTGTVIWDSQLLGFTFNDMFIRISTRLPSTYIYGFGETEHTTFKIDMNWQTWGMFSRDEPPGYKKNSYGVHPYYMGLEEDGNAHGVLLMNSNAMDVTFQPMPALTYRTTGGILDFYVFLGPTPEIVTQQYTELIGRPVMVPYWSLGFQLCRYGYENDTEIANLYDEMVAKQIPYDVQYSDIDYMERQLDFKLSPKFSGFPDLINRMKDNGMRVILILDPAISGNETEPYPAFTRGVENDVFISYPNNGGIVWGKVWPDYPNITVDPSLDWDSQVQQYRAYVAFPDFFRNSTALWWKNEIKELHSNSQDPAKSLKFDGLWIDMNEPSSFVNGAVPSGCTDTTLNRPPYMPHLEARDRGLSSKTLCMESEHILPDGSRVRHYDVHSLYGWSQTRPTYEAVQEVTGERGIVITRSTFPSSGRWGGHWLGDNTAAWDQLGKSIIGMMDFSLFGISYTGSDICGFFQDAEYEMCVRWMQLGAFYPFSRNHNTIGTKRQDPVSWNKTFEDISRSVLETRYTLLPYLYTLMYKAHKEGSTVVRPLLHEFLADRETWNVDKQFLLGPAFLVSPVLEPNARNVTAYFPKAQWYDYYTGADINSTGEWRTLPAPLEHINLHVRGGYILPWQQPALNTNLSRKKPLGLLIALNENKEARGELFWDDGQSKDTVAKNIYLFSEFSVTQNRLDVTISSPNYKDPNNLEFQEIKIFGTQEILNVKVKQNGVLLQMSPQVNYNSNQKVATITNIHLVLGEAYTVEWDIYSKDMERIDCYPDEHGVSEANCTARGCIWEVSNIPGVPHCYFANELYSVSNVQYDSHGATADISLKASPYSNAFPSTPVNQLQLKVTYHKDQMLQFKIYDPNHSRYEVPVPLNIPRTPSSTVDGRLYDVLIKENPFGIQIRRKSTGTVIWDSQLLGFTFNDMFIRISTRLPSTYIYGFGETEHTTFKIDMNWHTWGMFSRDEPPGYKKNSYGVHPYYMGLEEDGNAHGILLLNSNAMDVTFQPMPALTYRTTGGILDFYVFLGPTPEIVTQQYTELIGRPVMVPYWSLGFQLCRYGYENDAEIANLYDEMVAKQIPYDVQYSDIDYMERQLDFKLNPKFSGFPDLINRMKDNGMRVILILDPAISGNETEPYPAFTRGVENDVFIRYPNNGDIVWGKVWPDYPNIVVNSSLDWDSQVEQYRAYVAFPDFFRNSTALWWKKEIEELYRNTQEPAKSLKFDGLWIDMNEPSSFVNGAVPSGCSDTTLNRPPYMPYLEARDRGLSSKTLCMESEHILPDGSRVRHYDVHSLYGWSQTRPTYEAVQEVTGERGIVITRSSFPSSGRWGGHWLGDNTAAWDQLGKSIIGMMDFSLFGISYTGSDICGFFQDAEYEMCVRWMQLGAFYPFSRNHNTIGTRRQDPVSWNKTFEDISRSVLETRYTLLPYLYTLMYKAHTEGSTVVRPLLHEFVSDRETWSIDKQFLLGPAFLVSPVLEPDARNIRSYFPRALWYDYYTGENINSTGEWRTLSAPLEHINLHVRGGYILPWQRPALNTHLSRKNPLGLIIALDENKEARGELFWDDGQSKDLTTNNILCKFSVTQNRLDVSTSKSTYTDPDNLTFQEIKIFGTQALYNVTVKHNGMVNQMSPQVSYDPNMKVALITGIQLLLNESYTVEWDGSIRDGEKMDCYPDQHGASEANCTARGCVWEVSNSPGVPFCYFVNELYSVSNVQYDSHGASANISLKASPYSNAFPSTPVNELQLKVTYHKDEMLQFKIYDPNHSRYEVPVPLNIPSSPSSTPDNRSYDVFIKENPFGIEIRRKGTGSVIWDSRLLGFTFNDMFIRISTRLPSTYIYGFGETEHTTFKIDMNWHTWGMFSRDEPPGYKKNSYGVHPYYMGLEEDGNAHGILLMNSNAMDVTLQPMPALTYRTTGGVLDFFVFLGPTPELVTQQYTELIGRPVMVPYWSLGFQLCRYGYENDTEIANLYDDMVAKKIPYDVQYSDIDYMERQLDFKLNPKFSGFPDLINRMKHDGMRVILILDPAISGNETEPYPAFTKGVENDVFIRYPNNGDIVWGKVWPDYPNITVDPSLDWDSQVEQYRAYVAFPDFFRNSTALWWKDEIKELHSNTQDPAKSLKFDGLWIDMNEPSSFVNGAVPSGCSDATLNRPPYMPHLEARDRGLSSKTLCMESEHILPDGSRVRHYDVHSLYGWSQTRPTYEAVQEVTGERGIVITRSTFPSSGRWGGHWLGDNTAAWDQLGKSIIGMMDFSLFGISYTGSDICGFFQDAEYEMCVRWMQLGAFYPFSRNHNTIGTRRQDPVSWNKTFEDISRSVLETRYTLLPYLYTLMYKAHTEGSTVVRPLLHEFVSDRETWNIDKQFLLGPAFLVSPVLEPNARTVAAYFPKARWYDYYTGVDINARGEWKTLQAPLEYINLHVRGGYILPWQEPAMNTQLSRKKSMGLKAALNDEGLAEGWLFWDDGKSINI--TNQYYLARFSVSQNTLQTHEMFNNYITGTVPLYLGYIEIWGLSSPSITSVRISGKNLNEEVLADYNTTTQILRVNVTDKNISLHAFQSLTWS---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A571BF69-1", "uniprot_id": "A0A571BF69_MOUSE", "id": "A0A571BF69-1", "name": "Sucrase-isomaltase, intestinal", "aln": "MAGRRFKKFSKLELVLIVLLLVLFIIAVVLIVLLANSTPEN-------------------------AIGAETTGTPDTTVTRTTLNSPNCPVLSELERINCIPDQSSNKGTCDERGCCWDPQGSISVP-CYYSRNHGYKMESDVVNTNAGFTATLKNLPSAPVFGNSIENILLTAEYQTSNRFHFKLTDQTKKRYEVPHEHVQPFSGNAPSSLNYKVEVSKEPFSIKVTRKSNNRVLFDSSIGPLLFSDQFLQFSTHLPSANVYGLGEHVHQQYRHNMNWKTWPMFSRDTTPNEDGTNLYGVQTFFLCLEDNSGLSFGVFLMNSNAMEVTLQPTPAITYRTTGGILDFYVFLGNTPEQVVQEYLELIGRPALPSYWTLGFQLSRYDYKSLDNMKAVVERNRAAQLPYDVQHADIDYMDQKKDFTYDPVNFKGFPEFVKELHNNGQKLVIILDPAISNNSFSSNPYGPYDRGSAMKIWVNSSDGISPVIGKVWPGTTVFPDYTSPNCAVWWTKEFELFHKEVEFDGIWIDMNEVSNFIDGSFSGCSQNNLNYPPFTPKVLDGYLFSKTLCMDAVQHWGKQYDVHNLYGYSMAIATAKAVKDVFPDKRSFIITRSTFAGSGKFAAHWLGDNTATWKDLQWSIPGMLEFNLFGIPMVGADICGFAQDTYEELCRRWMQLGAFYPFSRNHNGQGYKDQDPASFGNNSLLLNSSRHYLNIRYTLLPYLYTLFYRAHSRGDTVARPLLHEFYDDNNTWGIDRQFLWGPGLLITPVLDQGAEKVKAYVPNATWYDYETGEELGWRKQSIEMQLPGDKIGLHLRGGYIFPTQQPATTTEASRKNPLGLIVALDENKEARGELFWDDGESKDTVAQNIYLFSEFSVTQNHLDVTISSPNYKDPNNLEFQEIKIFGTREFRNVRVKQNGNLLQMSPQVTYNPNLKVATITNIHLRLGEAYTVEWDFFTREEERIDCYPDEHGASEANCSARGCIWEASNTTRGPPCYFAHELYSVSNVQYDSHGATADISLKASTYSNAFPSTPVNKLKLQVTYHKNEMLQFKIYDPNHSRYEVPVPLNIPSAPLSTPEGRLYDVLIKENPFGIQIRRKTTGTVIWDSQLLGFTFNDMFIRISTRLPSTYIYGFGETEHTTFKIDMNWHTWGMFSRDEPPGYKKNSYGVHPYYMGLEEDGNAHGVLLMNSNAMDVTFQPMPALTYRTIGGILDFYVFLGPTPEIVTQQYTELIGRPVMVPYWSLGFQLCRYGYENDTEIANLYDEMVAKQIPYDVQYSDIDYMERQLDFKLSPKFSGFPALINRMKANGMRVILILDPAISGNETQPYPAFTQGVENDVFIRYPNNGGIVWGKVWPDYPNITVDSSLDWDIQVERYRAYVAFPDFFRDSTALWWKKEIKELHSNSQDQAKSLKFDGLWIDMNEPSSFVNGAVPSGCSDATLNHPPYMPHVEGRDRGLSSKTLCMESEHILPDGSRVRHYDVHSLYGWSQTRPTYEAMQEVTGERGIVITRSTFPSSGRWGGHWLGDNTAAWDQLGKSIIGMMDFSLFGISYTGSDICGFFQDAEYEMCVRWMQLGAFYPFSRNHNTIGTKRQDPVSWDKTFEDISRSVLETRYTLLPYLYTLMYKAHKEGSTVVRPLLHEFLADRETWNIDKQFLLGPAFLVSPVLEPNARNVTAYFPKAQWYDYYTGADINSTG-WTTLPAPLEHINLHVRGGYILPWQQPALNTNLSRKKPLGLLIALDEKKEARGELFWDDGQSKDTVAKNIYLFSEFSVTQNHLDVTISSPNYKDPNNLEFQEIKIFGTQEFSNVRVKQNGNLLQMSPQVTYNPNLKVATITNIHLRLGEAYTVEWGFFTREEERIDCYPDEHGASEANCSARGCIWEESNTIGVPTCYFAHELYSVSNVQYDSHGATADISLKASTYSNAFPSTPVNKLKLQVTYHKNEMLQFKIYDPNNSRYEVPVPLNIPSAPSSTNEGRLYDVLIKENPFGIQVRRKSTGTVIWDSQLLGFTFNDMFIRISTRLPSTYIYGFGETEHTTFKIDMNWHTWGMFSRDEPPGYKKNSYGVHPYYMGLEEDGNAHGVLLMNSNAMDVTFQPMPALTYRTTGGILDFYVLLGPTPEIVTQQYTELIGRPVMVPYWSLGFQLCRYGYENDSEIASLYDEMVDKQIPYDVQYSDIDYMERQLDFKLSPKFSGFPALINRMKANGMRVILILDPAISGNETQPYPAFTRGVENDVFIRYPNNGSIVWGKVWPDYPNITVDP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SLGWDHQVEQYRAYVAFPDFFRNSTATWWKKEIEELYTNTEEPEKSLKFDGLWIDMNEPSSFVNGAVPSGCSDATLNHPPYMPHVEGRDRGLSSKTLCMESEHILPDGSRVQHYDVHSLYGWSQTRPTYEAVQEVTGERGIVITRSTFPSSGRWGGHWLGDNTAAWDQLGKSIIGMMDFSLFGISYTGSDICGFFQDAEYEMCVRWMQLGAFYPFSRNHNTIGTKRQDPVSWNKTFEDISRSVLETRYTLLPYLYTLMYKAHMEGSTVVRPLLHEFVSDRKTWNIDKQFLLGPAFLVSPVLEPNARNISAYFPTALWYDYYTGANINSTGEWKTLPAPLEHINLHVRGGYILPWQRPALNTHLSRKNPLGLLIALDENKEARGELFWDDGQSKDLTTNNILCKFSVTQNRLDVSTLQSTYMNPDNLAFQEIKIFGTRPLYNVTVKHNGMVNQMAPQVSYDPSMKVAVITGLQLLLNESYTVEWDDSIRDEEKIDCYPDQHGASETSCTARGCVWEESNSDVVPFCYFVNELYSVSNVQYGSHGATANISLKASPYSGAFPSTPVKELQLQVTYHKNEMLQFKIYDPNHSRYEVPVPLNIPSAPSSTPESRLYDVLIKENPFGIEIRRKGTGTVVWDSQLLGFTFSDMFIRISTRLPSTYIYGFGETEHTTFKIDMNWNKWGMFSRDEPPGYRKNSYGVHPYYMGLEEDGNAHGVLLMNSNAMDVTFQPMPALTYRTTGGILDFYVFLGPTPEFVTQQYTELIGRPVMVPYWSLGFQLCRYGYENDSEIASLYDEMVDKKIPYDVQYSDIDYMERQLDFKLSPKFSGFPALINRMKANGMRVILILDPAISGNETEPYPAFTRGVENDVFIRYPNNGSIVWGKVWPDYPNITVDPSLGWDHQVEQYRAYVAFPDFFRNSTATWWKKEIKELHSNTQDPAKSLKFDGLWIDMNEPSSFVNGAVPSGCSDATLNHPPYMPYLEARDRGLSSKTLCMESEQILPDGSRVRHYDVHNLYGWSQTRPTYEAVQEVTGERGIVITRSTFPSSGRWGGHWLGDNTAAWDQLGKSIIGMMDFSLFGISYTGSDICGFFQDAEYEMCVRWMQLGAFYPFSRNHNTIGTRRQDPVSWNKTFEDISRSVLETRYTLLPYLYTLMYKAHTEGSTVVRPLLHEFVSDRETWNIDKQFLLGPAFLVSPVLEPNARKVEAYFPRARWYDYYKGVDINATGEWKTLEAPLEYINLHIRGGYILPWQEPAMNTHLSRQKFMGLRAALNAEGRAEGWLFWDDGKRIN---TDQYYLARFSVNQTTLLTHEKFNNYLTGTAPLYLGYIDIWGLSSSSITNVSISWNTNNEEVFANYNSTTKILSVNMTDKKISLHTFNSLTWSSS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43451-2", "uniprot_id": "MGA_HUMAN", "id": "O43451-2", "name": "Maltase-glucoamylase", "aln": "MARKKLKKFTTLEIVLSVLLLVLFIISIVLIVLLAKESLKSTAPDPGTTGTPDPGTTGTPDPGTTGTTHARTTGPPDPGTTGTTPVSAECPVVNELERINCIPDQPPTKATCDQRGCCWNPQGAVSVPWCYYSKNHSYHVEGNLVNTNAGFTARLKNLPSSPVFGSNVDNVLLTAEYQTSNRFHFKLTDQTNNRFEVPHEHVQSFSGNAAASLTYQVEISRQPFSIKVTRRSNNRVLFDSSIGPLLFADQFLQLSTRLPSTNVYGLGEHVHQQYRHDMNWKTWPIFNRDTTPNGNGTNLYGAQTFFLCLEDASGLSFGVFLMNSNAMEVVLQPAPAITYRTIGGILDFYVFLGNTPEQVVQEYLELIGRPALPSYWALGFHLSRYEYGTLDNMREVVERNRAAQLPYDVQHADIDYMDERRDFTYDSVDFKGFPEFVNELHNNGQKLVIIVDPAISNNSSSSKPYGPYDRGSDMKIWVNSSDGVTPLIGEVWPGQTVFPDYTNPNCAVWWTKEFELFHNQVEFDGIWIDMNEVSNFVDGSVSGCSTNNLNNPPFTPRILDGYLFCKTLCMDAVQHWGKQYDIHNLYGYSMAVATAEAAKTVFPNKRSFILTRSTFAGSGKFAAHWLGDNTATWDDLRWSIPGVLEFNLFGIPMVGPDICGFALDTPEELCRRWMQLGAFYPFSRNHNGQGYKDQDPASFGADSLLLNSSRHYLNIRYTLLPYLYTLFFRAHSRGDTVARPLLHEFYEDNSTWDVHQQFLWGPGLLITPVLDEGAEKVMAYVPDAVWYDYETGSQVRWRKQKVEMELPGDKIGLHLRGGYIFPTQQPNTTTLASRKNPLGLIIALDENKEAKGELFWDNGETKDTVANKVYLLCEFSVTQNRLEVNISQSTYKDPNNLAFNEIKILGTEEPSNVTVKHNGVPSQTSPTVTYDSNLKVAIITDIDLLLGEAYTVEWSIKIRDEEKIDCYPDENGASAENCTARGCIWEASNSSGVPFCYFVNDLYSVSDVQYNSHGATADISLKSSVYANAFPSTPVNPLRLDVTYHKNEMLQFKIYDPNKNRYEVPVPLNIPSMPSSTPEGQLYDVLIKKNPFGIEIRRKSTGTIIWDSQLLGFTFSDMFIRISTRLPSKYLYGFGETEHRSYRRDLEWHTWGMFSRDQPPGYKKNSYGVHPYYMGLEEDGSAHGVLLLNSNAMDVTFQPLPALTYRTTGGVLDFYVFLGPTPELVTQQYTELIGRPVMVPYWSLGFQLCRYGYQNDSEIASLYDEMVAAQIPYDVQYSDIDYMERQLDFTLSPKFAGFPALINRMKADGMRVILILDPAISGNETQPYPAFTRGVEDDVFIKYPNDGDIVWGKVWPDFPDVVVNGSLDWDSQVELYRAYVAFPDFFRNSTAKWWKREIEELYNNPQNPERSLKFDGMWIDMNEPSSFVNGAVSPGCRDASLNHPPYMPHLESRDRGLSSKTLCMESQQILPDGSLVQHYNVHNLYGWSQTRPTYEAVQEVTGQRGVVITRSTFPSSGRWAGHWLGDNTAAWDQLKKSIIGMMEFSLFGISYTGADICGFFQDAEYEMCVRWMQLGAFYPFSRNHNTIGTRRQDPVSWDAAFVNISRNVLQTRYTLLPYLYTLMQKAHTEGVTVVRPLLHEFVSDQVTWDIDSQFLLGPAFLVSPVLERNARNVTAYFPRARWYDYYTGVDINARGEWKTLPAPLDHINLHVRGGYILPWQEPALNTHLSRKNPLGLIIALDENKEAKGELFWDDGQTKDTVAKKVYLLCEFSVTQNHLEVTISQSTYKDPNNLAFNEIKILGMEEPSNVTVKHNGVPSQTSPTVTYDSNLKVAIITDINLFLGEAYTVEWSIKIRDEEKIDCYPDENGDSAENCTARGCIWEASNSSGVPFCYFVNDLYSVSDVQYNSHGATADISLKSSVHANAFPSTPVNPLRLDVTYHKNEMLQFKIYDPNNNRYEVPVPLNIPSVPSSTPEGQLYDVLIKKNPFGIEIRRKSTGTIIWDSQLLGFTFNDMFIRISTRLPSKYLYGFGETEHTSYRRDLEWHTWGMFSRDQPPGYKKNSYGVHPYYMGLEEDGSAHGVLLLNSNAMDVTFQPLPALTYRTTGGVLDFYVFLGPTPELVTQQYTELIGRPVMVPYWSLGFQLCRYGYQNDSEISSLYDEMVAAQIPYDVQYSDIDYMERQLDFTLSPKFAGFPALINRMKADGMRVILILDPAISGNETQPYPAFTR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GVEDDVFIKYPNDGDIVWGKVWPDFPDVVVNGSLDWDSQVELYRAYVAFPDFFRNSTAKWWKREIEELYNNPQNPERSLKFDGMWIDMNEPSSFVNGAVSPGCRDASLNHPPYMPYLESRDRGLSSKTLCMESQQILPDGSPVQHYNVHNLYGWSQTRPTYEAVQEVTGQRGVVITRSTFPSSGRWAGHWLGDNTAAWDQLKKSIIGMMEFSLFGISYTGADICGFFQDAEYEMCVRWMQLGAFYPFSRNHNTIGTRRQDPVSWDVAFVNISRTVLQTRYTLLPYLYTLMHKAHTEGVTVVRPLLHEFVSDQVTWDIDSQFLLGPAFLVSPVLERNARNVTAYFPRARWYDYYTGVDINARGEWKTLPAPLDHINLHVRGGYILPWQEPALNTHLSRQKFMGFKIALDDEGTAGGWLFWDDGQSIDTYGKGLYYLASFSASQNTMQSHIIFNNYITGTNPLKLGYIEIWGVGSVPVTSVSISVSGMVITPSFNNDPTTQVLSIDVTDRNISLHNFTSLTWISTL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** :::***:.**:** ****:***:::*******:.: . : *.***.**. * ** .:***:.* *********...* ***:*****:***::*** **:*:**.*::*.::.**.***** ****.*:****..::*:********************::*:*******:.*****.:**.*:**: ::********:****************:*****:**:***:***************:*******:* ****** :*.****.********* *****************.***:****** ****************************:*****:***:****:* :**:*: ***********************:::*****.*:********:************:******** **:********* **:******* .:**:**** *******.*******.**:****::****************:***.**** **** *****::*** **.****************:*********:** :*.* ***:*****:***********************.**:*****:************.****** :* ********************************** :*************************:******************:*..**.:.:***************:***** ****:*.*******.:: ****.:**:** ****************** *** **********:***:****:******:*::*****:::**: ***.***:*:*.**...******* *:****:**.* ** **:** * ** *.*:.***** **:*.* *********.: *:**:*******:*.* ** *******.**:. * ***.::*****::**:******** **:*.*:********* *:*.*:***::**********:.************ * *****:****:**:*****:****:***:***********.************.*:******** ::: *::*:********:**********************.******:***********:******* **:************:**:**************************:**:***.******* :*******************.*.***:*** ****** :*****************:******:***:**** ***:*.*********:*::.*: ***** **: ************:*** ***.**:**:.*.*: :******:***************..** *::**:******:*.**************::****** *:**:**.*************:*****:**:*************.************** *******:**********:***********************************:*******: :* :***.**:************* ***.** **********::*: **::*.*************** **********:*:*******.***: * * ******:***************:*****:****:****:***:*:***:*********:******::**:.*******:*:****...******* *:****:* :* ** **:** * ** *.*:.***** **:*:* *********.: :: *:*******:* * **:******* **: *** ***.::*****::**:***********:* ::********* *:*.*****::**********..************.**** **:****:**:*****::**:****:************************.*:*********::: *::*:********:**********************.******:***********:**********:*****:******:*****************************:**:**:.****** ********************.*****:*** ****** :*****************:******* ***:****:***:*.*********:*::.*: **.** *** **************** *** **:**:.*.*:* :******:***************..** **:**:*****:**:**************::****** *:**:**.*******************:**:*************.************** *******:**********:*******************************************: :* :***:**:*************:****** *************: **:**.*************** ***.* ****:*******.****** ****** ***::****:************:**:***:* **:: **: ** * ********: *: .. **** **..*.*: :* ****:*** ** ****:***:.* .:*.* ** . : :.**::* :::**::**** * **** ", "identical_positions": 2130, "similar_positions": 426, "identity": "46.89%" }, { "cls_id": "homologset.agr.MGI:1203500", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P56183-1", "uniprot_id": "RRP1_MOUSE", "id": "P56183-1", "name": "Ribosomal RNA processing protein 1 homolog A", "aln": "------------------------------MVPGVPLPPEIQLAQRLAGNEQVTRDRALRKLRKYIEARSQRATGGFTPDELLKVWKGLFYCMWMQDKPLQQEELGRTIAQLVHAFHTT-------------EAQHQFLKAFWQTMIREWVGIDRLRLDKFYMLMRMVLSESLKAVKARGWDERQIEQLLELLTTEILNPDS-QAPSGVKSHFLEIFLEELAKVGAAELTADQNLQFIDPFCQIAARTKDSQVLHKIIQSIFQTIVEQAPLAIEDIMNELDTQSGEGEASDGDDGEASDG------DDGEASDDDDGEASDGGDGDVADSDDSDGADDDDGDVSDGDGGDNDEGDSNKSSEGEQDLQDTPPKKLPAGTAHRAGPEADKEQAWDDEENAGPVLQFDYEALANRLFKLASRQSTPSQNRKRLYKV---------------IQKLRELAGGTFPEDDVPEKAYKKMLEGRRERKKKK-KRLPKPQPQNKEAGSEAESSSADPGPGRKRKRNRKTDEKAGQGGPPG---------------------KRRKP----GARAKGAGAQQPKKRIQSSQSAE---------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P56182-1", "uniprot_id": "RRP1_HUMAN", "id": "P56182-1", "name": "Ribosomal RNA processing protein 1 homolog A", "aln": "------------------------------MVSRVQLPPEIQLAQRLAGNEQVTRDRAVRKLRKYIVARTQRAAGGFTHDELLKVWKGLFYCMWMQDKPLLQEELGRTISQLVHAFQTT-------------EAQHLFLQAFWQTMNREWTGIDRLRLDKFYMLMRMVLNESLKVLKMQGWEERQIEELLELLMTEILHPSS-QAPNGVKSHFIEIFLEELTKVGAEELTADQNLKFIDPFCRIAARTKDSLVLNNITRGIFETIVEQAPLAIEDLLNELDTQ---------DEEVASD------------------------------SDESS------------EGGERGDALSQKRSE-----------KPPAGSICRAEPEAGEEQAGDDRDSGGPVLQFDYEAVANRLFEMASRQSTPSQNRKRLYKV---------------IRKLQDLAGGIFPEDEIPEKACRRLLEGRRQKKTKKQKRLLRLQQERGKGEKEPPSPGMERKRSRRRGVGADPEARAEAGEQPGTAERALLRDQPRGRGQRGARQRRRTPRPLTSARAKAANVQEPEKKKKRRE------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P35178-1", "uniprot_id": "RRP1_YEAST", "id": "P35178-1", "name": "Ribosomal RNA-processing protein 1", "aln": "-------------------------------------METSNFVKQLSSNNRKTRVNALEALKKYLTAKQFKEN---KQIEFNKLWKGLYYAMWFSDRPRPQQRLANELGELHGLYFDPKDNSTADELTTNDKAFIKFSRGFWKVMCFEWFNIDRYRLDKYLLLIRRVLFSQLKYLQSRNWDKKLVDEYIKKVLRWLPLSGSPKVYTGIPIHIVDILLDEWERLLK------------------------------------------------------------------------------------------------------------------------DGDEDDEDEENKEEE--------------------------------------------------------MRKIAESAKKTPLADV---------------IAIFQDIVADYNNSKVLREKIKEDLFSDTR----LVSWDILEGETQHNDSSNESEEEEEEEWKGF---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VJZ7-1", "uniprot_id": "RRP1L_DROME", "id": "Q9VJZ7-1", "name": "Ribosomal RNA processing protein 1 homolog", "aln": "MVTRKKPVKRNAEAAEIQVEQEEDASQPKVAKELMVVAQEVKIIRALACNDVVERNRQIRILRKWFKAR-AGSSFPFNEDDFMRIWKGLYYTMWMSDKPLVQEELAEKLAQMVDSFGGN------------TACSLAYFSAFMRTMCQEYFGIDQWRMDKFLMLTRRMVRYLLRFLKQNNWNADLIAAFNSSMQLSVMSEQP--KSRGMTMHYLDVFFEELAKAANGEITAAQVNMFLRPFVTYIATQRDAKLVAQCRTRVLYHLMYQSDLGRQYSEKYNAWKQMGFPTASIDDIEKLDSGFDEEDDEVNAEEEQPRATSLDPRAGNVDVHMPELPLNADCVLDELQTQLRTNDFNSKRRKGLRKLIQIFETYQRGEFPLGVRTMPKVEGQTLSEMVEQKVAALDKMEDEVFATGRKLKKLNKSKRKRLLQSINFEEVDEHNYDEVISKALPPELQKKVNYNAKVRSSINNAWVVEEVKEAEPKSKKAKKEEPPQQNKDDQTKVKKKSQLKPKNDQSKPKIEDQPTLKAEKEEPAKRKKLDHSKTKEEQSKPKTDEQPKPTPKVEGQSKAKPTPKTKAAGVDDDAPTNGWDAPLEDGEQDIFVPSRKLQVKQANSKLPQSTPKQPARAEFATPQTGSGKHVRIVTKSNCIYPKSDYYRQLKLSPQVPYDANRLPGKSALKPHWIPGPIHPSYKAKRLFNDTL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : *: *: * . :. *:*:: *: . :: ::****:* **:.*:* *:.*.. :.:: : . : .* :.* *: .**: *:**: :* * :: *: :: ..*: : . : : . *: * ::::::* : : : ..* : :: * .: * .: :: . : .. . . . : . . .:. . ", "identical_positions": 35, "similar_positions": 89, "identity": "4.99%" }, { "cls_id": "homologset.agr.MGI:1203517", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JHY7-1", "uniprot_id": "BIRC5_RAT", "id": "Q9JHY7-1", "name": "Baculoviral IAP repeat-containing protein 5", "aln": "------------MGATALPPIWQM-YLKDHRIYTFKNWPFLEDCSCTPERMAEAGFIHCPTENEPDLAQCFFCFKELEGWEPDDNPIEEHRKHSPGCAFLTVKKQVEELTVSEFLKLDKQRAKNKIAKETNNKQKEFEETRRTVRQSIEQLAALR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70201-1", "uniprot_id": "BIRC5_MOUSE", "id": "O70201-1", "name": "Baculoviral IAP repeat-containing protein 5", "aln": "------------MGAPALPQIWQL-YLKNYRIATFKNWPFLEDCACTPERMAEAGFIHCPTENEPDLAQCFFCFKELEGWEPDDNPIEEHRKHSPGCAFLTVKKQMEELTVSEFLKLDRQRAKNKIAKETNNKQKEFEETAKTTRQSIEQLAA--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15392-1", "uniprot_id": "BIRC5_HUMAN", "id": "O15392-1", "name": "Baculoviral IAP repeat-containing protein 5", "aln": "------------MGAPTLPPAWQP-FLKDHRISTFKNWPFLEGCACTPERMAEAGFIHCPTENEPDLAQCFFCFKELEGWEPDDDPIEEHKKHSSGCAFLSVKKQFEELTLGEFLKLDRERAKNKIAKETNNKKKEFEETAKKVRRAIEQLAAMD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VEM2-1", "uniprot_id": "Q9VEM2_DROME", "id": "Q9VEM2-1", "name": "", "aln": "MESPVVNEVAASLGGEKLEVFRKLNLLEQHRVESYKSWPFPETASCSISKMAEAGFYWTGTKRENDTATCFVCGKTLDGWEPEDDPWKEHVKHAPQCEFAKLSCPERNLTVSQFLEILGTVVKGSIEKTCKAFKSSFVRENEKRLDEFTRNQK--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*. * : *:::*: ::*.*** * .:*: .:****** *:.* * * **.* * *:****:*:* :** **:. * * .:. .:**:.:**:: .*..* * : :..* . .. : : ", "identical_positions": 45, "similar_positions": 46, "identity": "29.03%" }, { "cls_id": "homologset.agr.MGI:1203520", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88764-1", "uniprot_id": "DAPK3_RAT", "id": "O88764-1", "name": "Death-associated protein kinase 3", "aln": "MSTFRQEDVEDHYEMGEELGSGQFAIVRKCQQKGTGMEYAAKFIKKRRLPSSRRGVSREEIEREVSILREIRHPNIITLHDVFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQILDGVHYLHSKRIAHFDLKPENIMLLDKHAASPRIKLIDFGIAHRIEAGSEFKNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGETKQETLTNISAVNYDFDEEYFSSTSELAKDFIRRLLVKDPKRRMTIAQSLEHSWIKVRRR-----EDGARKPERRRLRAARLREYSLKSHSSMPRNTSYASFERFSRVLEDVAAAEQGLRELQRGRRQCRERVCALRVAAEQREARCRDGSAGLGRDLRRLRTELGRTEALRTRAQEEARAALLGAGGLKRRLCRLENRYDALAAQVAAEVQFVRDLVRALEQERLQ-AECGVR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O54784-1", "uniprot_id": "DAPK3_MOUSE", "id": "O54784-1", "name": "Death-associated protein kinase 3", "aln": "MSTFRQEDVEDHYEMGEELGSGQFAIVRKCQQKGTGMEYAAKFIKKRRLPSSRRGVSREEIEREVSILREIRHPNIITLHDVFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQILDGVHYLHSKRIAHFDLKPENIMLLDKHAASPRIKLIDFGIAHRIEAGSEFKNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGETKQETLTNISAVNYDFDEEYFSSTSELAKDFIRRLLVKDPKRRMTIAQSLEHSWIKVRRR-----EDGARKPERRRLRAARLREYSLKSHSSMPRNTSYASFERFSRVLEDVAAAEQGLRELQRGRRQCRERVCALRAAAEQREARCRDGSAGLGRDLRRLRTELGRTEALRTRAQEEARAALLGAGGLKRRLCRLENRYDALAAQVAAEVQFVRDLVRALEQERLQ-AECGVR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43293-1", "uniprot_id": "DAPK3_HUMAN", "id": "O43293-1", "name": "Death-associated protein kinase 3", "aln": "MSTFRQEDVEDHYEMGEELGSGQFAIVRKCRQKGTGKEYAAKFIKKRRLSSSRRGVSREEIEREVNILREIRHPNIITLHDIFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQILDGVHYLHSKRIAHFDLKPENIMLLDKNVPNPRIKLIDFGIAHKIEAGNEFKNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGETKQETLTNISAVNYDFDEEYFSNTSELAKDFIRRLLVKDPKRRMTIAQSLEHSWIKAIRRRNVRGEDSGRKPERRRLKTTRLKEYTIKSHSSLPPNNSYADFERFSKVLEEAAAAEEGLRELQRSRRLCHEDVEALAAIYEEKEAWYREESDSLGQDLRRLRQELLKTEALKRQAQEEAKGALLGTSGLKRRFSRLENRYEALAKQVASEMRFVQDLVRALEQEKLQGVECGLR", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******************************:***** ************.***************.***************:********************************************************************:...************:****.**********************************************************************.*********************************. ** **..********:::**:**::*****:* *.***.*****:***:.****:*******.** *:* * ** . *::** *: * .**:****** ** :****: :*****:.****:.*****:.******:*** ***:*::**:*********:** .***:*", "identical_positions": 379, "similar_positions": 52, "identity": "83.48%" }, { "cls_id": "homologset.agr.MGI:1203522", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q96QZ7-1", "uniprot_id": "MAGI1_HUMAN", "id": "Q96QZ7-1", "name": "Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1", "aln": "MSKVIQKKNHWTSRVHECTVKRGPQGELGVTVLGGAEHGEFPYVGAVAAVEAAGLPGGGEGPRLGEGELLLEVQGVRVSGLPRYDVLGVIDSCKEAVTFKAVRQGGRLNKDLRHFLNQRFQKGSPDHELQQTIRDNLYRHAVPCTTRSPREGEVPGVDYNFLTVKEFLDLEQSGTLLEVGTYEGNYYGTPKPPSQPVSGKVITTDALHSLQSGSKQSTPKRTKSYNDMQNAGIVHAENEEEDDVPEMNSSFTADSGEQEEH----TLQETALPP--VNSSIIAAPITDPSQKFPQYLPLSAEDN-LGPLPENWEMAYTENGEVYFIDHNTKTTSWLDPRCLNKQQKPLEECEDDEGVHTEELDSELELPAGWEKIEDPVYGIYYVDHINRKTQYENPVLEAKRKKQLEQQQQQQQQQQQQQQQQQQQQTEEWTEDHSA--LVPPVIPNHPPSNPEPAREVPLQ-------GKPFFTRNPSELKGKFIHTKLRKSSRGFGFTVVGGD-----EPDEFLQIKSLVLDGPAALDGKMETGDVIVSVNDTCVLGHTHAQVVKIFQSIPIGASVDLELCRGYPLPFDPDDPNTSLVTSVAILDKEPIIVNGQETYDSPASHSSKTGKVNG-----MKDARPSSP-ADVASNSSHGYPNDTVSLASSIATQPELITVHIVKGPMGFGFTIADSPGGGGQRVKQIVDSPRCRGLKEGDLIVEVNKKNVQALTHNQVVDMLVECPKGSEVTLLVQRGGLPVPKKSPKSQPLERKDSQNSSQHSVSS--HRSLHTASPSHSTQVLP----EFPPAEAQAP-----DQTDSSGQKKPDPFKIWAQSRSMYENRPMSPSPASGLSKGEREREINSTNFGECPIPDYQEQDIFLWRKETGFGFRILGGNEPGEPIYIGHIVPLGAADTDGRLRSGDELICVDGTPVIGKSHQLVVQLMQQAAKQGHVNLTVRRKVVFAVPKTENEVP-SPASSHHSSNQPASLTEEKRTPQGSQNSLNTVSSGSGSTSGIGSGGGGGSG--VVSTVVQPYDVEIRRGENEGFGFVIVSSVSRPEAGTTFAGNACVAMPHKIGRIIEGSPADRCGKLKVGDRILAVNGCSITNKSHSDIVNLIKEAGNTVTLRIIPGDESSNATLLTNAEKIATITTTHTPSQQGTQETRNTTKPKQESQFEFKAPQAT----------QEQDFYTVELERGAKGFGFSLRGGREYNMDLYVLRLAEDGPAERCGKMRIGDEILEINGETTKNMKHSRAIELIKNGGRRVRLFLKRGDGSVPEYDPSSDRHGPATGPQGVPEVRAGP-DRRQHPSLESSYPPDLHKSSPHGEKRAHARDPKGSREYSRQPNEHHTWNGTSRKPDSGACRPKDRAPEGRRDAQAERAAAANG-------------------PKRRSPEKRREGTRSADNTLERREKHEKRRDVSPERRRERSPTRRRDGSPSR-------RRRSLERLLEQRRSPERRRGGSPERRAKSTDRRR--------------------------------------------------------------------------------------ARSPERR------------------RERSLDKRNREDRASHREREE----------ANLKQDAGRSSRHPPEQRRRPYKECSTDLSI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6RHR9-1", "uniprot_id": "MAGI1_MOUSE", "id": "Q6RHR9-1", "name": "Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1", "aln": "MSKVIQKKNHWTGRVHECTVKRGPQGELGVTVLGGAEHGEFPYVGAVAAAEAAGLPGGGEGPKLAEGELLLEVQGVRVSGLPRYDVLGVIDSCKEAVTFKAVRQGGRLNKDLRHFLNQRFQKGSPDHELQQTIRDNLYRHAVPCTTRSPREGEVPGVDYSFLTVKEFLDLEQSGTLLEVGTYEGNYYGTPKPPSQPVSGKVITTDALHSLQSGSKQSTPKRTKSYNDMQNAGIVHPENEEEEDVPEMNSSFTADSGDQDEH----TLQEATLPP--VNSSILAAPITDPSQKFPQYLPLSAEDN-LGPLPENWEMAYTENGEVYFIDHNTKTTSWLDPRCLNKQQKPLEECEDDEGVHTEELDSELELPAGWEKIEDPVYGVYYVDHINRKTQYENPVLEAKRKKQLEQQQQQQQPQPPQ--------PEEWTEDHAS--VVPPVAPSHPPSNPEPARETPLQ-------GKPFFTRNPSELKGKFIHTKLRKSSRGFGFTVVGGD-----EPDEFLQIKSLVLDGPAALDGKMETGDVIVSVNDTCVLGHTHAQVVKIFQSIPIGASVDLELCRGYPLPFDPDDPNTSLVTSVAILDKEPIIVNGQETYDSPASHSSKTGKVSS-----MKDARPSSP-ADVASNSSHGYPNDTVSLASSIATQPELITVHIVKGPMGFGFTIADSPGGGGQRVKQIVDSPRCRGLKEGDLIVEVNKKNVQALTHNQVVDMLIECPKGSEVTLLVQRGGLPVPKKSPKSQPLERKDSQNSSQHSVSS--HRSLHTASPSHGIQVLP----EYLPADAPAP-----DQTDSSGQKKPDPFKIWAQSRSMYENRPMSPSPASGLSKGERDREINSTNFGECQIPDYQEQDIFLWRKETGFGFRILGGNEPGEPIYIGHIVPLGAADTDGRLRSGDELICVDGTPVIGKSHQLVVQLMQQAAKQGHVNLTVRRKVVFAVPKAENEVP-SPASSHHSSNQPASLTEEKRTPQGSQNSLNTVSSGSGSTSGIGSGGGGGSG--VVSAVLQPYDVEIRRGENEGFGFVIVSSVSRPEAGTTFG------------RIIEGSPADRCGKLKVGDRILAVNGCSITNKSHSDIVNLIKEAGNTVTLRIIPGDESSNATLLTNAEKIATITTTHAPSQQGTQETRTTTKPKQDSQFEFKGPQAA----------QEQDFYTVELERGAKGFGFSLRGGREYNMDLYVLRLAEDGPAERCGKMRIGDEILEINGETTKNMKHSRAIELIKNGGRRVRLFLRRGDGSVPEYDPSSDRNGPSTGAQGVPEVRPGPPDHRPHPALESSYPPELHKSSQHAEKRAHAKDPKGNREHSKQPNEHHTWNGTSRKQDSGACRPKDRPPDAWREAQPER-TATNG-------------------SKRRSPEKRREGTRSADNTLERREKHEKRREISPERKRERSPTRRKDSSPSR-------RRRSLERLLDQRRSPERRRGGSPERRAKSTDRRR--------------------------------------------------------------------------------------ARSPERR------------------RERSLDKRNRDDKVGHREREE----------AGLKLEAGRSPRNPPEQRRRPYKECSTDLSI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4L1J4-1", "uniprot_id": "MAGI1_RAT", "id": "Q4L1J4-1", "name": "Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1", "aln": "MSKVIQKKNHWTGRVHECTVKRGPQGELGVTVLGGAEHGEFPYVGAVAAAEAAGLPGGGEGPKLAEGELLLEVQGVRVSGLPRYDVLGVIDSCKEAVTFKAVRQGGRLNKDLRHFLNQRFQKGSPDHELQQTIRDNLYRHAVPCTTRSPREGEVPGVDYSFLTVKEFLDLEQSGTLLEVGTYEGNYYGTPKPPSQPVSGKVITTDALHSLQSGSKQSTPKRTKSYNDMQNAGIVHTENEEEEDVPEMNSSFTADSGDQDEP----TLQEATLPP--VNSSALAAPITDPSQKFPQYLPLSAEDN-LGPLPENWEMAYTENGEVYFIDHNAKTTSWLDPRCLNKQQKPLEECEDDEGVHTEELDSELELPAGWEKIEDPVYGVYYVDHINRKTQYENPVLEAKRKRQLEQQQQQQQHQQQPQQPQPPQ-PEEWTEDHAS--VVPPVAPSHPPSNPEPAREAPLQ-------GKPFFTRNPSELEGKFIHTKLRKSSRGFGFTVVGGD-----EPDEFLQIKSLVLDGPAALDGKMETGDVIVSVNDTCVLGHTHAQVVKIFQSIPIGASVDLELCRGYPLPFDPDDPNTSLVTSVAILDKEPIIVNGQETYDSPASHSSKTGKVSN-----MKDARPSSP-ADVASNSSHGYPNDTVSLASSIATQPELITVHIVKGPMGFGFTIADSPGGGGQRVKQIVDSPRCRGLKEGDLIVEVNKRNVQALTHNQVVDMLIECPKGSEVTLLVQRGGLPVPKKSPKSQPLERKDSQNSSQHSVSS--LRSLHTASPSHSAQVLP----EYPPADVPAP-----DQTDSSGQKKPDPFKIWAQSRSMYEDRPMSPSPASGLSKGERDREINSTNFGECQIPDYQEQDIFLWRKETGFGFRILGGNEPGEPIYIGHIVPLGAADTDGRLRSGDELICVDGTPVIGKSHQLVVQLMQQAAKQGHVNLTVRRKVVFTVPKAENEVP-SPASSHHSSNQPASLTEEKRTPQGSQNSLNTVSSGSGSTSGIGSGGGGGSG--VVSAVLQPYDVEIRRGENEGFGFVIVSSVSRPEAGTTFAGNACVAMPHKIGRIIEGSPADRCGKLKVGDRILAVNGCSITNKSHSDIVNLIKEAGNTVTLRIIPGDESSNATLLTNAEKIATITTTHAPSQQGTQETRTTTKPKPDSQFEFKGPQAT----------QEQDFYTVELERGAKGFGFSLRGGREYNMDLYVLRLAEDGPAERCGKMRIGDEILEINGETTKNMKHSRAIELIKNGGRRVRLFLRRGDGSVPEYGGSNYENIPS-----FPGMTP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M2B284-1", "uniprot_id": "A0A8M2B284_DANRE", "id": "A0A8M2B284-1", "name": "Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1", "aln": "MSKVVQKKNHWTTKVNECSVSKDARGELNVQLLGGAENGEFAYIGHVNETAVQYRNG-----KVSEGELLLEVETLSVSGLPLYDVLTVIKNCKGPIRLKTVRQGHKLNKDLKHYLSQRFQKSSADYELQQTIRDNLYRHAVPCTTRPPREGEVPGVDYNFLSVDEFLKLEQSGTLLEIGSYEGNYYGTPKPPIKPPSGKVITGDALQDSLPGSQPSTPRRTKSYNEMQNAGIVPTETEDDDEVPEMNSSFTGDSSEPDDHPSVRPFARDQLQP--YGLNNTSASTTESSQNTHTHPAYPTEEDPLGPLPENWEMAYTENGEVYFIDHNTKTTSWIDPRCLDKPQKPLEECEDDEGVHTEELDNELELPTGWEKIDDPVYGVYYVDHINRKTQYENPILEAKRKKQLEQSQPAEGERFIQ----------EWIDEHSSGAPLASYAANHQETYRDPGTGPPLPTQLGAKRGKPFFTRNPAELKGTFINTKLKKSRRGFGFTVVGGD-----EPDEFLQIKSLVLDGPAALDGKMETGDVIVSVNDTCVLGYTHAQVVKIFQSIPIGSMVDLELCRGYPLPFDPDDPNTSLVTSVAILDKEPIIVNGKESYDSPSSHGSETTAGGSSLNGSSDPPRPHSPSAEVASNGSHGYPSDVVTLASSIATQPELITVHMEKGDKGFGFTIADSPSGGGQRVKQIVDYPRCRGLREGDIIMEVNKRNVQNLTHNQVVDLLSKCPKGSEVTMLVQRG-VAPAKKSPKLQQLERKDSQGSSQHSVSS--QRSIHTDSPLHASQALLNESAAPPPPSQPLPSLPQDPPVDGTLQKKPDPFKIWAQSRSMYESR----------------------------LPDYQEQDIFLWRKDTGFGFRILGGNEPGEPIYIGHIVKYGAADEDGRLRSGDELICVDGTAVVGKSHQLVVQLMQQAAKQGHVNLTVRRKTGYGLAKVDGEMPPSPASSHHSSTQAPSLTEEKRTPQGSQNSLNTVSSGSGSTSGIGSGGGGGSNNTVIPNAILPYDVEIQRGENEGFGFVIVSSVSRPEAGTTFAGNACVAMPHKIGRIIEGSPADRCGKLKVGDRILAVNGCSITNKSHSDIVNLIKEAGNTVTLRIIPGDESSNASLLTNAEKIATITTTHTPQQQAAPEPRNNTKPKQES-FEFKAPQAPPPPAPTQSSNQDAEFYSVDLERDNKGFGFSLRGGREYNMDLYVLRLAEDGAAVRNGKMRVGDEILEINGESTKGMKHARAIELIKNGGRKVHLVLRRGDGSVPEYDGINDGNGLGAGAQTVSEVNSAPPESRPHPPSESSYPPDLHKSSRNDNKRTRESGQREHGHRSNHRHNNHRHRSPEKKSRSKGHGKDSGTSKSHRKKGDKKKSSTDDSHHHHHHHSNSRNQYHHHRQRHRSPERRR--TRSAGDTLDSR--HTQRNGRSPDRRHHRHSSPRRHSSPHRSPHRSGYRRSSPYRNRSPYRSPQRSRYQSPSRRPTDKEFDRGIDVTLKEPPPPKPPSRSESIPLLDRLSLEDTVMREPPSYRRDLSPMERAYRESTLLRGASRDGTFPRVRTPESDSAFRNYNSLLRGRSPVRVGNRHDAYRRDQSPVASSYRTRSLGRDLSPIRGFRDEEEEEVESQLSEYYSPLRSNYSRANNNVPEPRRNAYRESPKDLSI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W2L2-1", "uniprot_id": "Q9W2L2_DROME", "id": "Q9W2L2-1", "name": "", "aln": "---------MPIITATTTSTAGGGAGVAARGVATAKSPTDYLMLQQQQQQQQQQQQHFNSNHFYQQQQPQQLAPLNASHQHQHSHPHPHPHPVAAATSFATFNGNSNLNSSLANGSSRKFNCSRDNVDDGGDAG----EMAAASQTLSSAGTDVVGNGSGHGNGTVTGNGEKSGGLAPPGGHH--LRPPPPPALKKSASAVIGNSASREDVASLSGTSSLNSQMSVHNQFISGLPSNGIGSNGVHGGAATGRGGPPNSILKGSKENLLQNTYYNGETGDSSLGSECGVGDVQHQNHESHDDPGDGLGPLPPKWETAYTERGELYFIDHNTGTSHWLDPRLSKYQKKSLEDCCED------------ELPYGWEKIEDSMYGMYFIDHVNRRTQYENPVLEAKRRAAEQSQQQQQMQQQQQ--------QMQEQRSKTPTALSETMPTEAAEAHEQEEDESPMK-------LPYKFTRNPAELQGQRINTTLLKSSRGLGFTIVGSDGSAGGDVEEFLQIKTVVPNGPAWLDGQLQTGDVLVYVNDTCVLGYTHHDMVNIFQSILPGERAALEVCRGYPLPFDPNDPNTEVVTTMAVDGRE---SDKQRRLNMDGNYNFLDLSGEG---------------AKKTSGSGSGF---------ILMKKPEIYTFSIMKGSMGFGFTIADSACG--QIVKKILDRNCCTQLMEGDVLLEINGLNVRNKPHFYVVELLKECSQTTPTAVKIQRTPPDPPANNTLAQLNQVGNVAKLRKNFVGSGLFRSKTPTADLYSTQVKEVLPMRPKTPLVDTR------RSRVQIQSPNNEVDDEGDGAAAAERKP----------------------------LQLQTQGKSNSSLQELDDIPYMDPYPKISRLSERLAEVTLQGDANGGIYGMPPSMQPLPLPLAHHESCYCYDCQAQRYRPGYFVQAQQAAMSGTTGQYSPLQTAHLQNERIQRRVNELLSDRRRVGFANLDPPQQMQHSPSWRNGALLDVSEDAD------QCELTEVTLER-QALGFGFRIVGGTEEGSQ-------------VTVGHIVPGGAADQDQRINTGDEILSIDGINVLNSSHHKVVSLVGES-------------------ALRGQVTMILRRRRTPLLQQAPVSTQLRR---------------------------YPYDVIVSRHENEGFGFVIISSSNHYYGSTIGKLIPGSPADRCGELKVGDRIVAVNRIEIAGMSHGDVVNLIKESGLHVRLTIG-----VPLKEGGPSPGGSSVGVSSNTPLQASPSLLKAQLSHQQQLPQQHLQQAQLNHHHQHLEMPMSMPVPGHGSYLERPSNNISATLALHQQPQL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :. . * : . . :: : : : . . . . : :.. . .**..* : .::*: . : : . *... * .. :* * . .. . . *:** * * :. .* *. : :. ** .* :. .. . ::. .:: . * . : .: .: * :: ... : : . . . .: . : : . : ***** :** ****.**:******: *: *:*** . :*.**:* :* *** *****:*.:**:*::**:**:******:*****: :..* : : : .::. . .. : : *: *****:**:* *:*.* ** **:***:**.* : :******::* :*** ***:::****:* ********:** ::*:***** * . **:**********:****.:**::*: .:* : :. : ..:. . *. :*... *: : .:**: *. : ** *********. * * **:*:* * * ***:::*:* **: .* **::* :*.: : .:: :** . :.. * : : :: *.* ** . : :. *. .. *. : .. .:. : * : : * *. : .: :. . : .* :* : . : .: :. : * : *:. : : : . . ..: . *::.:*. .. :. : :. ... .* . . .:. :* :.* : **** **..... . :*: *..**: :::.**.**:::* .: *.** .:*.*: *: ..: : ::* * : . : : : .: :**** : .. :: . : :* ...* * *::::**.*: :* .*.*. .::***:.* :*:* : ** . . : . ", "identical_positions": 258, "similar_positions": 350, "identity": "15.33%" }, { "cls_id": "homologset.agr.MGI:1203524", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97496-1", "uniprot_id": "SMRC1_MOUSE", "id": "P97496-1", "name": "SWI/SNF complex subunit SMARCC1", "aln": "--MAATAGGG-PGAAAGAVGAGGAAAASGLAVYRRKDGGPASKFWESPDTVSQLDSVRVWLGKHYKKYVHADAPTNKTLAGLVVQLLQFQEDAFGKHVTNPAFTKLPAKCFMDFKAGGTLCHILGAAYKYKNEQGWRRFDLQNPSRMDRNVEMFMNIEKTLVQNNCLTRPNIYLIPDIDLKLANKLKDIIKRHQGTFTDEKSKASHHIYPYPSSQEDEEWLRPVMRRDKQVLVHWGFYPDSYDTWVHSNDVDAEIEDAPIPEKPWKVHVKWILDTDVFNEWMNEEDYEVDENRKPVSFRQRISTKNEEPVRSPERRDRKASANSRKRKPSPSPPPPTATESRKKSGKKGQASLYGKRRSQKEEDEQ-EDLTKDMEDPTPVPNIEEVVLPKNVNPKKDSENTPVKGGTVADLDEQDEEAVTTGGKEDEDPSKGDPSRSVDPGEDNVTEQTNHIIIPSYASWFDYNCIHVIERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEYLTSTACRRNLTGDVCAVMRVHAFLEQWGLVNYQVDPESRPMAMGPPPTPHFNVLADTPSGLVPLHLRSPQVPAAQQMLNFPEKNKEKPIDLQNFGLRTDIYSKKTLAKSKGASAGREWTEQETLLLLEALEMYKDDWNKVSEHVGSRTQDECILHFLRLPIEDPYLENSDASLGPLAYQPVPFSQSGNPVMSTVAFLASVVDPRVASAAAKAALEEFSRVREEVP-LELVEAHVKKVQEAARASGKVDPTYGLESSCIAGTGPDEPEKLEGSEEEKMETDPDGQQPEKAENKVENE--SDEGDKIQDRENE------KNTEKEQDSDVSEDVKPEEKENEENKELTDTCKE--RESDAGKKKVEHEISEGNVATAAAAALASAATKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREKEALEQQRQQLLTERQNFHMEQLKYAELRARQQMEQQQQHGQTPQQAHQHTGGPGMAPLGATGHPGMMPHQQPPPYPLMHHQMPPPHPPQ---PGQIPGPGSMMPGQPMPGRMIPAVAANIHPTGSGPTPPG-MPPMPGNILGPRVPLTAPNGMYP--PPP-QQQQPPPPADGVPPPPAPGPPASATP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AMA8-1", "uniprot_id": "A0A8I6AMA8_RAT", "id": "A0A8I6AMA8-1", "name": "", "aln": "--MATTAGGG-PGAAAGAVGAGGAAAASGLAVYRRKDGGPASKFWESPDTVSQLDSVRVWLGKHYKKYVHADAPTNKTLAGLVVQLLQFQEDAFGKHVTNPAFTKLPAKCFMDFKAGGTLCHILGAAYKYKNEQGWRRFDLQNPSRMDRNVEMFMNIEKTLVQNNCLTRPNIYLIPDIDLKLANKLKDIIKRHQGTFTDEKSKASHHIYPYPSSQEDEEWLRPVMRRDKQVLVHWGFYPDSYDTWVHSNDVDAEIEDAPIPEKPWKVHVKWILDTDVFNEWMNEEDYEVDENRKPVSFRQRISTKNEEPVRSPERRERKASANARKRKHSPSPPPPTATESRKKSGKKGQASLYGKRRNQKDEDEQ-EDLTKDMEDPTPVPNIEEVLLPKNVNPKKDSENTPVKGGTVADLDEQDEEAVTTGGKEDEDPSKGDPSRSADAGEDNVTEQTNHIIIPSYASWFDYNCIHVIERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEYLTSTACRRNLTGDVCAVMRVHAFLEQWGLVNYQVDPESRPMAMGPPPTPHFNVLADTPSGLVPLHLRSPQVPAAQQMLNFPEKNKEKPIDLQNFGLRTDIYSKKTLAKSKGASAGREWTEQETLLLLEALEMYKDDWNKVSEHVGSRTQDECILHFLRLPIEDPYLENSDASLGPLAYQPVPFSQSGNPVMSTVAFLASVVDPRVASAAAKAALEEFSRVREEVP-LELVEAHVKKVQEAARASGKVDPTYGLESSCIAGTGPDEPEKLEGSEEEKMETDPDGQQPEKAENKGENE--SDEGDKIQDGENE------KNSEKERDSDTSEDVKPEEKENEENKELTDTCKE--RESDTGKKKVEHEISEGNVATAAAAALASAATKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREKEALEQQRQQLLTERQNFHMEQLKYAELRARQQMEQQQ-HGQPPQQAHQHPGGPGLAPLGAAGHPGMMPHQQPPPYPMMHHQMPPPHPPQ---PGQIPGPGSMMPGQPMPGRMIPTVAANIHPTGSGPTPPG-MPPMPGNILGPRVPLTAPNGMYP--PPP-QQP-PPPPADGVPPPPVPGPPASATP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q92922-1", "uniprot_id": "SMRC1_HUMAN", "id": "Q92922-1", "name": "SWI/SNF complex subunit SMARCC1", "aln": "--MAAAAGGGGPGTAVGATGSGIAAAAAGLAVYRRKDGGPATKFWESPETVSQLDSVRVWLGKHYKKYVHADAPTNKTLAGLVVQLLQFQEDAFGKHVTNPAFTKLPAKCFMDFKAGGALCHILGAAYKYKNEQGWRRFDLQNPSRMDRNVEMFMNIEKTLVQNNCLTRPNIYLIPDIDLKLANKLKDIIKRHQGTFTDEKSKASHHIYPYSSSQDDEEWLRPVMRKEKQVLVHWGFYPDSYDTWVHSNDVDAEIEDPPIPEKPWKVHVKWILDTDIFNEWMNEEDYEVDENRKPVSFRQRISTKNEEPVRSPERRDRKASANARKRKHSPSPPPPTPTESRKKSGKKGQASLYGKRRSQKEEDEQ-EDLTKDMEDPTPVPNIEEVVLPKNVNLKKDSENTPVKGGTVADLDEQDEETVTAGGKEDEDPAKGDQSRSVDLGEDNVTEQTNHIIIPSYASWFDYNCIHVIERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEYLTSTACRRNLTGDVCAVMRVHAFLEQWGLVNYQVDPESRPMAMGPPPTPHFNVLADTPSGLVPLHLRSPQVPAAQQMLNFPEKNKEKPVDLQNFGLRTDIYSKKTLAKSKGASAGREWTEQETLLLLEALEMYKDDWNKVSEHVGSRTQDECILHFLRLPIEDPYLENSDASLGPLAYQPVPFSQSGNPVMSTVAFLASVVDPRVASAAAKAALEEFSRVREEVP-LELVEAHVKKVQEAARASGKVDPTYGLESSCIAGTGPDEPEKLEGAEEEKMEADPDGQQPEKAENKVENE--TDEGDKAQDGENE------KNSEKEQDSEVSEDTKSEEKETEENKELTDTCKE--RESDTGKKKVEHEISEGNVATAAAAALASAATKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREKEALEQQRQQLLTERQNFHMEQLKYAELRARQQMEQQQ-HGQNPQQAHQHSGGPGLAPLGAAGHPGMMPHQQPPPYPLMHHQMPPPHPPQ---PGQIPGPGSMMPGQHMPGRMIPTVAANIHPSGSGPTPPG-MPPMPGNILGPRVPLTAPNGMYP--PPPQQQPPPPPPADGVPPPPAPGPPASAAP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1Q9K1-1", "uniprot_id": "F1Q9K1_DANRE", "id": "F1Q9K1-1", "name": "", "aln": "MATAATAAGG-----TGSGGPSAGQTGAGSSIGRKKDGGPSSKYWESSETVSQLETVRLWIGKHYKKHVQTDSPTSKTLAALVVQLLQFQEDAFGRRVSNPALTKLPAKSFLDFKPGGALCHILGSAYKFKSEQGWRRFDLQNPSRMDRNVEMFMTIEKTLVQNNSLTRPIVYIVSDVEQKQANKLKDIIKRHQGTITEDKSKATHIIYPSPTQMEEEEWLRPVMRKDKQVLVHWGYYPDSYDIWVSTSDVDADVEDPPSSEKPWRVHAKWVIDTDAFNEWMNEEDYEVDENKKPVSFRQRIFPGEDVSSRTPDRKERKSLVAGKKRRRSPSPPS-TPVESRKK-GKKGNPGSQWRRRGQPIDDEQDEDSTKDLEDPSPVPGMEEVTLPKNVNQKKDSENTPVKGGIHNDLDDQEDDSVTSGGKEDDEQSKAEVNRLID-SEDNVTEQTHHIIIPSYAAWFDYNSIHEIERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEYLTSTSCRRNLTGDVCAVMRVHAFLEQWGLVNYQVDAESRPLPMGPPPTSHFNVLADTPSGLVPLHHRPPQVPPAQQMLNFPEKGKDKPTDLQNFGLRTDIYSKKNLK-GKGAAGGRDWTEQETLLLLEALEMYKDDWNKVSEHVGSRTQDECILHFLRLPIEDQYLESSDASLGPLAYQPIPFSQSGNPVMSTVAFLASVVDPRVAAAAAKAALDEFSRVREEVP-AELVEAHVKKVQEAARSTGKVDPAFGLESSGIAGTAPEEPEKTEPTETEKMDTDSDSQQPDKAESKDEAEKPSESAEKPAETEKEKIETTEKSEPQEEEESEAGETKTAEKEKEEAMETTEEGKEDEEEQEEGKKKLELDIGEGNIATAAAAALASAATKAKHLAAVEERKIKSLVALLVETQMKKLELKLRHFEELETIMDREKEALELQRQQLLTERQAFHMEQLKYAEMKARQQMEQQAAVQQNAG-GHHGPPPHGPPPGMHPGHPGHPGHPGPG-FPPMHHPMGPHHTPQ---TGPMVGP-----GQPMPGRMM-----------SGPPPQGGIAPMMG----PRHPG-PPNGMYPGPPPPTAQPDGMPPGPVGPPPSVPATRAAEN-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P43609-1", "uniprot_id": "RSC8_YEAST", "id": "P43609-1", "name": "Chromatin structure-remodeling complex protein RSC8", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSDTEKDKDVPMVDSHEATE--EPPTTSTNTPSFPHLAQEQAKEESATLGAEVAHKKINYEQEAQKLEEKALRFLAKQTHPVIIPSFASWFDISKIHEIEKRSNPDFFNDSSRFKTPKAYKDTRNFIINTYRLSPYEYLTITAVRRNVAMDVASIVKIHAFLEKWGLINYQIDPRTKPSLIGPSFTGHFQVVLDTPQGLKPFLPEN--VIKQEVEGGDGAEPQVKKEFPVNLTIKKNVYDS---AQDFNALQDESRNSRQIHKVYICHTCGNESINVRYHNLRARDTNLCSRCFQEGHFGANFQSS----------DFIRLENNGN----SVKKNWSDQEMLLLLEGIEMYEDQWEKIADHVGGHKRVEDCIEKFLSLPIEDNYIREVVGSTLNGKGGDSRDGS------------------------------------------------------------------------------------------VSGSKLMECVNDAVQTLLQGDDKLGKVSDKSREISEKYIEESQAIIQELVKLTMEKLESKFTKLCDLETQLEMEKLKYVKESEKMLNDRLSLSKQILDLNKSLEELNVSKKLVLISEQVDSGIQLVEKDQEGDDEDGNTATGHGVKRVGKEGEEVGEGDSIAKL---QPQVYKPWSL-------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P32591-1", "uniprot_id": "SWI3_YEAST", "id": "P32591-1", "name": "SWI/SNF complex subunit SWI3", "aln": "-----------------------------------------------------------------------------------------MENTLGEGSTVNASVDVDQHGNDNNSDSNANAAVAGVANTDTAGE-----ESQQQDESLKDEATVPNTRDAESEAITVTAKQQPTMQANKLDSQETPSTEESRAQNVFGQDNEDSDNLFGETESSVSNNEANTPSIP---------------------TNPVDNENNKP-----------------------------AIKEDSTIQDSNGDVKNMEDVKIQKEEEPENNTVIEGVKEESQPDENTKEMDEVEEDDEDDDQPMISPDNSIFGDTKSESKQLGNTSSVANTPSEIPDAHKAEQEDIIEKTESVDKKVDSGEERNEQEREIMN---DHSKSANPKKTTITRVEPETFEIPQAHEIVIPSYSKWFNLEKIHSIEVQSLPEFFTNRIPSKTPEVYMRYRNFMVNSYRLNPNEYFSVTTARRNVSGDAAALFRLHKFLTKWGLINYQVDSKLLPKNIEPPLTSQYSTRHDAPRGLFPFESYKPSVQLPDMAKLKKMMNTSDSESTLYKYLKESKRKYDEITHPPSTTDDENGDKNDNGGKMNNEVSTSTSMTGDANLLEE---GETSRPLKKVKILEQIDEN-----------------------------WSKEDLQKLLKGIQEFGADWYKVAKNVG-NKSPEQCILRFLQLPIEDKFLYGDGNGKGDNDNGLGPLKYAPHLPFSKSENPVLSTIAFLVGLVNPKTVQS-----------------------------------------------MTQRAIQSAESIKSQKEEISDQKPIEHIKEGSEIAISSLGYRSHIFATNEERQMNFLTNELIRLQMEKLDAKLNHLKKLEKFMELERKTLERQQENLLIQRLNFNQNSSKIVNVLSKCLNLISDSNINNSSVAEKEEIRSQIDHFKSMLSKPETLSIGKNPFNKPNIETGENHNGQSISNENDVKPISIEAPQFYRYWSA--------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . . : . .: : : .. : .:: : ... . *:: ::***:: **: . ** ** :: *:**.. ***: * ***::::***.* **:: *: ***:: *..::.::* ** :***:***:*.. * : *. * ::.. *:* ** *: * : . :: . . .: ... ..: . . . . : . : . : .. * : . : :: :: ..* : * : :. . . : . . * . .: :. : . :.. . ::: :: .: : : *:. *:**: *: :: .**. :: *: : :::* :* : : . : . . . . . * ", "identical_positions": 65, "similar_positions": 154, "identity": "5.77%" }, { "cls_id": "homologset.agr.MGI:1203527", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9PWP7-1", "uniprot_id": "E9PWP7_MOUSE", "id": "E9PWP7-1", "name": "", "aln": "MSTRRWVRQTAALCLLAFILHSLPRHIAAENGTTESGSVWDGGGNSTQDDSQE---TQFRTVLKTKTTDGENSEAWPRQEYQQRSSSPSTTKAEVTTTADVTTTADVTTTAEITTTSDVTTTAEITNTDDVTTTGEVTTTADVTTTSDVPTTSEVTSTDDVITTAEVTTTAEMTPTDDVTTTSEVTTTGDVTTTGDVTITGDLTTTADVTTKADFTTTDDVTTTADGSTTADLTTTAKVTTTDDVTTTGEITTTSEITTTSDVTTTAEITTTDIVTTTG---EVTTTADVTTTSDVTTTSEETPTADITTTADLTTTAEVTTTDDVTTTVEITTTSEITTTSDVTTIAEITTTDIVTTTGEVTTTADVTTTSDVTTTSEETTTADITTTADLTTTAEITTTDDVTTTVEITTTSDVTTTTEITTTDIVTTTGEVTTTADVTTASDVTTTSEETPTADITTTADLTTTAEVTTTDDVTTT-GEVTTTADVTTTSDVTTTSEETTTADVTTTSDVTTTAEITTTDDITSTADVTTTADVTTTSDVPTTSEETTTADVTTTSDVTTTAEITTTDDITSTADVTTTADVTTTSDVTTTTEENPTADITTTADLTTTAEVTTTDDVTTTVEITTTSEITTTSDVTTTAEITTTDIVTTTDEDTTTADVTTTSDVTTTSEETPTADITTTADLTTTADVTTTSDVTTTSEETTTADVTTTSDVTTTAEITTTDDITSTADVTTTTNVTTTSDVPTTSEVTSTDDVITTTEVTTTAEIIPTDDVTTTSEVTTTGDVTTTGDVTMTGDLTTTADVTTTADLTTTDEVTTTADGSTTADLTTTAEVTTTDDVTTTVQITTTSEITTTSDVTTTAEITTTDNVTTTGEVTTTADVTTTSDVTTTSEETPTADITTTADLNTTAEVTTTEDVTTTVEITTTSEITTTSDITTTAEITTTDIVTTTGEVTTTADVTTTNDVTTTSEETPTADITTTADLTTTAEITTTDDITSTADVTTTTDVTTTSDVPTTSEVTSTDDVITTTEVTTTAEIIPTDDVTTTSEVTTTGDVTTTGDVTMTGDLTTTADVTTTADLTTTDEVTTTADGSTTADLTTTAEVTTTDDVTTTVQITTTSEITTTSDVTTTAEITTTDNVTTTGEVTTTADVTTTSDVTTTSEETPTADITTTADLTTTAEVTTTEDVTTTVEITTTSEITTTSDITTTAEITTTDIVTTTGEVTTTADVTTTNDVTTTSEETPTADITTTADLTTTAEITTTDDVTTTGEVTTTADVTTTSDVTTTSEETPTADITTTADLTTTAEITTTDDVTTTGEVTTTADVTTTSDITTTSEETPTADITTTADLTTTAEVTTTDDVTTTGEVTTTADVTTTSDITTTSEETPTADITTTADLTTTAEVTTTDDVTTTVEITTTSEITTTSDVTTTAEITTTDIVTTTGEVTTTADVTTTSDVTTTSEQTPTADITTTADLTTTAEVTTTDDVTTTVEITTTSEITTTSDVTTTAEITTTDIVTTTGEVTTTADITTTSDVTTTSEETTTADVTTTTDVTTTSEETTTGDGKTTTAEITTTDDITTTADVTTTPDVTTTAAVTTTGEITPTDDVTTTSEVTTTGDVTSTGDVTTTGEVTTTAEVTTTADVTTTSDVTTTSEETPTADITTTADLTTTAEVTTTDDVTTTGEVTTTADVTTTSDTTTTSEETPTADITTTVDLTTTAEVTTTDDVTTTVEITTTSEITTTSDVTTTAEITTSDIFTTTGEVTTTADITTTSDVTTTSEETPTADITTTADLTTTAEITTTDDVTTTVEITTTSEITTTSEVTTTPDVTTTSDVTTTSEETPTADITTTADLTTTAEVTTTDDVTTTVEITTTSEITTTSDVTTTAEITTTDIVTTTGEVTTTVDVTTTNDVTTTSEETPTADITTTADLTTTAEVTTTDDVTTTGEVTTTADVTTTSDITTTSEETPTADITTTVDLTTTVEIT----TTSEITTTSDVTTTAEITTTDIVTTTGEVTTTADVTTTSDVTTTSEETPTADITTTADLTTTAEVTTTDDVTTTVEITTTSEITTTSDVTTTAEITTTDIVTTSGEVTTTADVTTTSDVTTTSEETTTADVTTTTDVTTTSEETTTGDGTTTTAEITTTDDLTTTADVTTTPDVTTTAAVTTTAEITPTDDVTTTSEVTTTGDVTTTGEVTTTAEVTTTDDVTTTGDVTTTGDLTTMADVTTTADFTTTDDVTTTADASTTADLATTAEVTTTDDVTTTVEITTTAEITTTAEVTTTDDVTTTGEVTTTADVTTTTDVTTTSEVTTTADVTTTNDVTTTAEITTTDDITTTADVTTTADVTTTSYVPTTSEVTSTDDVTTTAEVTTTAEITPTDDVTTTSEVTTTGDVTTTGDVTMTCDLTTSADVTTTADFTTTDDVTTKADGSTTADLTTTAEVTTNDDVTTTGELTTTAEITTTSDVTTTAEITTTDIVTTTGEVTTTADVTTTSDVTTTSEETTTADITTTADLTTTAEVTTTDDVTTTVEITTTSEITTTSDVTTIAEITTTDIVTTTGEVTTTADVTTTNDVTTTSEETPTADITTTADLTTTAEVTTTDDVTTTGEVTTTADVTTTSDVTTTSEETPTADITTTADLTTTAEVTTTDDVTTTVEITTTSEITTTSDVTTTAEITTTDIVTTTGEVTTTADITTTSDVTTTSEETTTADVTTTTDVTTTSEETTTGDGKTTTAEITTTDDITTTADVTTTPDVTTTAAVTTTGEITPTDDVTTTSEVTTTGDVTTTGDVTTTGEVTTTAEVTTTDDVTTTGDVTTTGDLTTTADVTTTAYFTTTDDVTTTADGSTTADLTTTAEVTTTDDVTTTVEITTTAEITTTDDVTTTGEVTTTADVTTTSDVTTTSEETPTADITTTADLTTTAEVTTTDDVTTTVEITTTSEITTTSD---VTTTAEITTTDIVTTTGEVTTTADVTTTSDVTTTSEETPTADITTTADLTTTAEVTTTDDVTTTVEITTTSEITTTSDVTTTAEITTTDIVTTTGEVTTTADVTTTSDVTTTSEETPTADITTTADLTTTAEVTTTDDVTTTVEITTTAEITTTDDVTTTGEVTTTADVTTTAEVITTSDVTTTADVTTMPDFTTTAEVTTTLDVTTNDEVTTTSVVTTTPEITTAGDVTTTSEVTTSADLTTTPEITTTGDVTTTADVTTTADITTTSDVTTTADVTTTADITTTSDVTTTADVTTIADLSTTPEITTTGDFSSTTDVTSTGDVTTTADVTTTADVTTTGDVTTTAEVTTTAEVTTTAEATTTADLNTTPEITTTDDVTTTGDVTITAEVTTTAYVTTTTDFTTTAEVNTTDDVTTIADLTTTAEVTTTNDVTSTAEITTTADLTTTTEVTTTADFITTGDVTTTADVTTMADVTTTADVTTADLTTTVDVTTMDDVTTTAEVITSGDVTTTSEVTTTSNLNTTPEITTTIDFTSTVDVTTTGDVTTTADVTTTSDVTTTSKVTTTGDVTTTADTTSTADVTTTADVITTAEVTTTADFTNTGDVTTSADVTTTADLTTMPDLTTTAEVTTTADVTTTSEFTTTADVTTTADVTSTADVTTTAEVTTTGDVTTTADVTNTGDITTIGDVTTTTEITTTAYLTTTLEITTTGEVTSTADVTTSAEVTTTDEITTTDVVTTTGDVTPTAESTTTDDVTTTSDVTTTGDFTTTADVTTTAYVTTTPDVTTTVEVTTTADFTTTGVVNTTADVTTTADVTTTSEVTTTADLTTTPEITTTVDFTSTADVTTTADVITTPEVTTTSDVTTTAEVITTADVTTTADVTTTVEVTTTGDVTITADVTTTPEITTTVDFTSTADVTITADVTTTADVTTTSDVTITPDVTTTAEVTTTVEITTTDDVTTTGEVTTTADVTTTSDVTTTSEETTTADITTTSDVSTTSEVTT---TAYVTTTADTTSTAEVT--TTADVTTTADVTTTADVTTTADVTTTVEVTTTGDVTTTADVTTTAEVTTTAEITTTGDVTTTADVTTTAEVTTTAEITTTGDVTTTADVTTTADVTTTADVT-TTIDVTTTADVTTSAEVTTTADVTTTTEVTTTTEVATTPEPTTTPAPTTTAVNCMNGGFWTGDKCICPNGFGGDRCEN---IVNVVNCENGGTWDGLKCQCTSLFYGPRCEELVESVEIEP--TVAASVEVSVTVTSQEYSEKLQDRKSEEFSNFNKTFTKQMALIYAGIPEYEGVIIKNLSKGSIVVDYDVILKAKYTPGFENTLDTVVKNLETKIKNATEVQVQDVNNNCSALLCFNSTATKVQNSATVSVNPEETCKKEAGEDFAKFVTLGQKGDKWFCITPCSAGYSTSKNCSYGKCQLQRSGPQCLCLITDTHWYSGENCDWGIQKSLVYGLGGAGVAVLLVILVILLVFSIRFRKDAQRQRSRVSEMYKWGEEEGRASPGTFHNFGFDHNEERENYMPLDSVYNTFQPSLNHINPERKIQIQRPQVVMTSL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q685J3-1", "uniprot_id": "MUC17_HUMAN", "id": "Q685J3-1", "name": "Mucin-17", "aln": "----MPRPGTMALCLLTLVLSLLPPQAAAEQDLSVNRAVWDGGGCISQGDVLNRQCQQLSQHVRTGSAANTATGTTSTNVVEPRMYLSCSTNPEMTSIESSVTSDTPGVSSTRMTPTESRTTSESTSDSTTLFPSSTEDTSSPTTPEGTDVPMSTPSEESISSTMAFVSTAPLPSFEAYTSLTYKVDMSTPLTTSTQASSSPTTPESTTIPKSTNSEGSTPLTSMPASTMKVASSEAITLLTTPVEISTPVTISAQASSSPTTAEGPSLSNSAPSGGSTPLTRMPLSVMLVVSSEASTLSTTPAATNIPVITSTEASSSPTTAEGTSIPTSTYTEGSTPLTSTPASTMPVATSEMSTLSITPVDTSTLVTTSTEPSSLPTTAEATSMLTSTLSEGSTPLTNMPVSTILVASSEASTTSTIPVDSKTFVTTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTLSTTPVDTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTPADSNTFVTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVSTTLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSEASTLSTTPVDTSTPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMP-VSKTLLTSSEASTLSTTPLDTSTHITTSTEASCS-PTTTEGTSMPISTPSEGSPLLTSIPVSITPVTSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTSMPVSTTLVATSAISTLSTTPVDTSTP-VTNSTEARSSPTTSEGTSMPTSTPGEGSTPLTSMPDSTTPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTPSEGTTPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTPADTSTPVTTYSQASSSSTTADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEAS-SSPTTAEGTSIPTSPPSEGTTPLASMPVSTTLVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTSTPGERSTPLTSMPVRHTPVASSEASTLSTSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEGSTLLTSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMPTSTYSEGRTPLTSIPVNTTLVASSAISILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSEASTLSATPVDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSIPVSNTPVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIAISTPSEGSTALTSIPVSTTTVASSEINSLSTTPAVTSTPVTTYSQASSSPTTADGTSMQTSTYSEGSTPLTSLPVSTMLVVSSEANTLSTTPIDSKTQVTASTEASSS--------TTAEGSSMTISTPSEGSPLLTSIPVSTTPVASPEASTLSTTPVDSNSPVITSTEVSSS---PTPAEGTSMPTSTYTEGRTPLTSITVRTTPVASSAISTLSTTPVDNSTPVTTSTEARSSPTTSEGTSMPNSTPSEGTTPLTSIPVSTTPVLSSEASTLSATPIDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHTLVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIATSTPSEGSTALTSIPVSTTTVASSETNTLSTTPAVTST-PVTTYAQVSSSPTTADGSSMPTSTPREGRPPLTSIPVSTTTVASSEINTLSTTLADTRTPVTTYSQASSSPTTADGTSMPTPAYSEGSTPLTSMPLSTTLVVSSEASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTSTPSERTTPLAG-MPVSTTLVVSSEGNTLSTTPVDSKTQVTNSTEASSSATAEGSSMTISAPSEGSPLLTSIPLSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPIPTEGTSMQTSTYSDRRTPLTSMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEARSSPTTS--EGTSMPTSTPSEGSTPFTSMPVSTMPVVTSEASTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGTTPLTSIPVSHTLVANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTMVASFETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMPTSTYSEGSTPLTSVPVSTMPVVSSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTP-VVSSEAGTLSTTPVDTSTPMTTSTEASSSPTTAEDIVVPISTASEGSTLLTSIPVSTTPVASPEASTLSTTPVDSNSPVVTSTEISSSATSAEGTSMPTSTYSEGSTPLRSMPVSTKPLASSEASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTNILVSTTLLANSEASTLSTTPVDTSTPVTTSAEASSSPTTAEGTSMRISTPSDGSTPLTSILVSTLPVASSEASTVSTTAVDTSIPVTTSTEASSSPTTAEVTSMPTSTPSETSTPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAEGIVVPISTASEGSTLLTSIPVSTTPVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVASSEASTLSRTPADTSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSAISTLSTTPVDTSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILSTTPVDSNTPLTTSTEASSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPADTSTPVTTYSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTPVDTSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTTPLASMPVSTTPVVSSEVNTLSTTPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTPVASSEASTLSTTPVDTSTPVTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTTPVDSNTFVTSSSQASSSPATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTPSTPSVDRSTPVTTSTQSNSTPTPPEVITLPMSTPSEVSTPLTIMPVSTTSVTISEAGTASTLPVDTSTPVITSTQVSSS-PVTPEGTTMPIWTPSEGSTPLTTMPVSTTRVTSSEGSTLSTPSVVTSTPVTTSTEAISS---SATLDSTTMSVSMPMEISTLGTTILVSTTPVTRFPESSTPSIPSVYTSMSMTTASEGSSSPTTLEGTTTMPMSTTSERSTLLTTVLISPISVMSPSEASTLSTPPGDTSTPLLTSTKAGSFSIPAEVTTIRISITSERSTPLTTLLVSTTLPTSFPGASIASTPPLDTSTTFTPSTDTASTPTIPVATTISVSVITEGSTPGTTIFIPSTPVTSSTADVFPATTGAVSTPVITSTELNTPSTSSSSTTTSFSTTKEFTTPAMTTAAPLTYVTMSTAPSTPRTTSRGCTTSASTLSATSTPHTSTSVTTRPVTPSSESSRPSTITSHTIPPTFPPAHSSTPPTTSASSTTVNPEAVTTMTTRTKPSTRTTSFPTVTTTAVPTNTTIKSNPTSTPTVPRTTTCFGDGCQNTASRCKNGGTWDGLKCQCPNLYYGELCEEVVSSIDIGPPETISAQMELTVTVTSVKFTEELKNHSSQEFQEFKQTFTEQMNIVYSGIPEYVGVNITKLRLGSVVVEHDVLLRTKYTPEYKTVLDNATEVVKEKITKVTTQQIMIN-DICSDMMCFNTTGTQVQNITVTQYDPEEDCRKMA-KEYGDYFVVEYRDQKPYCISPCEPGFSVSKNCNLGKCQMSLSGPQCLCVTTETHWYSGETCNQGTQKSLVYGLVGAGVVLMLIILVALLMLVFRSKREVKRQKYRLSQLYKWQEEDSGPAPGTFQNIGFDICQD-DDSIHLESIYSNFQPSLRHIDPETKIRIQRPQVMTTSF", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * *****:::* ** : ***:. : . :****** :*.* : *: ::* :: . : : . : : * ..:*:.*:*: . .*: .:: *.:: **:* *. . . .... *:. **.... .. ...* :.: :* ..:** :.. : *: : . . **. : :. *. : . .*: : . *: .** :: * . * * : :* ::: :::. .: ..::.: : .:. :. :..:*:.:* * ..:::*.. :. :::. **::..: ... * .. . ** :: ::*::: * : . *: :.*** .:: *: * *: *: : *. *:* : :: :..*:* : :. :***:.*.:::. .: :.::*:: . :: :*: . **.. : :.:::** : .* . .:* :. :..: *..: .:*.*: :*. :.. :. ::. ::* ..*... ...: .: ::. :**.: *: . *.::. *. :::..:: :..:*:.:**: . :: .*:. :::. **::..: ... : * ** .:*: ::::: * : . : .*** :*:*. *. . .*: * : *: *.** :: *.. :*: * *:: :**: : :*:. .: :.:.*:: :: :** * .* .:: *. :.* : *::.:**: :.: : .* * . : : : * *: *: *. *. *. :*: * :.. ***:.:::::. : :.:.*:: :*: ** . .:: * ::**. :*.*. :*.::: .::. .: .:.*:. :: :*: .* **.. : : :::* *:*. .*:*: .::.: *: *:*.. **. :*. . * .*: ::* **. * *. .:: . ..* *: ...: :*. ... . .:.. * * . *.: *..: : :.. :*****:: . * : *. .*..:.::..:** :* * ... :.*..* .. :: . .***: *: . ..:. ** *.:..:: *..::*..* . ... : .::. ::* .*: : . .. ... *: . . *:::. .* ::. . *: .**: *::. .*: * .*: .: * : *: :.* :. *. *: : *.. *.*:.**:::. : :.:.*:: . : :*: . ** . :: . ::** .:*. .*:*. ::.: . *: .:... **. .: . ..*..*. ::: :*. *.:*.. :: :.* : .:*.*: .*. :. *.:: ..: . ::* ..*..*. :..* *:.*. .*.:: *: * *.:: *: .:..:: .::*::.: * .:.:....** ::*. **:.. . *: : . *: *:* *:: * . :* * .. :**:::*.::: .*: *. * : : : : *: *:**. :* *. :*: : :.: * *: :*::: .*.*: *: . :* *. .** :.**. . .::: ::* . ... . ..*:. : *. **: : .: .: * .. *: .:*: * ::. .* :* *: .**: :*:. .*: .** :: *:. *: * ..: :. .*: : :.: :.*:: *::: : ..*:*:: :: :*: . *** : *. ::** **:* *** :: :.:. : :.:.*:: :*: ***. : . ::** :* *. * : ::.. .*. : * *: ::** :*:: ... :*: * *:: .**::* :.:. : :.: *:: * :: : ::** ::: .:. :*: : :. **.* *.:::* . :* . ::..* :. .: . ..*..:. :: .**.. . :.. * .:. . ..: *: : * : . ** .:..:: *.::. ::* . ... :....*:.. : .. **: * .:*.:: :*. ..: ...:. *:* ..*..* *... * ::. .**** *: * : .*. :.:..: :.:.***:* : ... .:.. *:. ::. .*: ..: .:..:: . .* * .** *:: * :: : *. .** . : :. .*: . *. : .: *:. .:* *:::*. :*: : *:: ***. :.::: : :.*.*:. *: ::: : **. *:: *.. :*: * *:: **::: :::. : *. : :. :*: . **. . : ::** : :.: **:* :::... ** *.* . :*. : ...... . :: **..*.: . .:* :..:**: *: ::*.:**:*: . :..:*. ::* ..*.. * . * *.. .***: :: . *. ...*. ::: .:* : :.** :* . . *: .**. :::: .*: :: : . .: *:* . .:: ....:* * *: ***::*.::: .: . .:.*: *:: :*: . *. : :. ***. *:*. .*:*. ::.. . :* . :* .: ....*..:. ::: .*...* : .. :* .. :.* *:: *:*.**::*. *:*.. : . :* * * : ***:::.:::. : :.:. :: : :*: . * .* : :* :: *. *:*. *:*: ::. . *. :*.. :*. : ... *..* ::: **. * .:.* :* .. :.* *: ::* :: :*. :..* ...*:.. : . *.. *.. * .. .*** *: * *.: . *. : :..*: *..:.* :* . ... :....*:. :**..*: . .*: : *:. *:. . *: ..* :* ..*.* :*:: :.:::. .: :.:.*: :: :*: . ***. :: *: *.*** *:* .* : : .. . *: *:* . :*. .* : ..*.:.. ::: **. *.::.. :* *.*:.** *: :..: **. .:: ....:. ..: **.** .*: .:* *. .: *: .:***: .*. .* . . : . ::* ..*.. *..: :.*.. .**.:**: . :*: . *. ::: .:: .:::: :. . ....::. .*:. : .. :* .* ...: .. : *: : ::: ***: *.:: . . .**: :*: .. . . : : .: * : ::**. . * *..::: * *: : *: *::: *** . : . : * ** .:** .:: . . :**.*.*:. ***::: :: .:* * ** : . . * : : .:. .* . :**..:.:. :: . .: *. .** * ** ::**:: :* : .. . ::: : ::. *.. * ::. .: .*. : . .** ::**.: :*. . . .*. :: *.. *.:** :* : .*.* ::** .**. :* :* * ::.:*. *:***:* **. *:*.. .:* :..:*:. :**...:** :.**.* .*::. . .* . :.: **: . **:*.. :::. . *. .** **.::: : .: :* ** * .. :::. .*:::..*...*..** . *.*.. **. **.*:. .. ..: *. * . .. .*:************..*:** ***:*.*::* * *::*.:*::***** :::*:*:::.*:**.:*::***:** ::*:***** ** *.:* **:**::**:*::**** ::..**...: :: **.:.* *: : ** ::***:*.*:*** :... :*** *:* * :::..:..: :.:* :**:**..*:*.****. ****:. *******: *:*******.*: * ******** ****.::*:*** **:: :* :::.:**: *:*::*** **:. .:****:*:*** :: :: : *:*:*..*****.**:** **:******: **:", "identical_positions": 939, "similar_positions": 1961, "identity": "20.76%" }, { "cls_id": "homologset.agr.MGI:1203727", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZAG0-1", "uniprot_id": "D3ZAG0_RAT", "id": "D3ZAG0-1", "name": "Semaphorin-6A", "aln": "-----------------------------------------------------------MRPAALLLCLTLLRCAGAGFPEDSE---------PISISHGNYTKQYPVFVGHKPGRNTTQRHRLDIQMIMIMN-RTLYIAARDHIYTVDIDTSHTEEIYCSKKLTWKSRQADVDTCRMKG-KHKDECHNFIKVLLKKND--DTLFVCGTNAFNPSCRNYRVDTLETFGDEFS-----GMARCPYDAKHANIALFADG-------KLYSATVTDFLAIDAVIYR--------SLGDSPTLRTVKHDSKWLKEPYFVQAVDYGDYIYFFFREIAVEYNTMGKVVFPRVAQVCKNDMGGSQRVLEKQWTSFLKARLNCSVPGDSHFYFNILQAVTDVIR----INGRDVVLATFSTPYNSIPGSAVCAYDMLDIANVFTGRFKEQKSPDSTWTPVPDERVPKPRPGCCAGSSSLEKYATSNEFPDDTLNFIKTHPLMDEAVPSIINRPWFLRTMVRYRLTKIAVDNTAGPY--ENHTVVFLGSEKGIILKFLARIGSSGFLNGSLFLEEMNVYNPEKCSYDGVEDKRIMGMQLDKAS----GSLYVAFSTCVIKVPLGRCER-HGKCKKTCIASRDPYCGWVKETGSCAHLSPLSRLAFEQDIERGNTDGLGDCHNSFVALNGRASSLYPSTTTSDSASRDGHESQGGMLDWNDLLKAPGNTDPLGAVSSHNHQDKKGVIRESYLKSNDQLVPVTLLAIAVILAFVMGAVFSGIIVYCVCDHRRKDVAVVQRKEKELTHSRRGSMSSVTKLSGLFGDSQSKDPKPEAILTPLMHNGKLATPSNTAKMLIKADQHHLDLT--ALPTPESTPTLQQKRKPNRGSREWERNQNLINACTKDMPPMGSPVIPTDLPLRASPSHIPSVVVLPITQQGYQHEYVDQPKMSEVVAQMALEDQAATLEYKTIKEHLSSKSPNHGVNLVENLDSLPPKVPQREASLGPTGASLSQTGLSKRLEMQHSSSYGLEYKRSYPTNSLTRSHQATTLKRNNTNSSNSSHLSRNQSLGRGDNPPPAPQRVDSIQVHSPQPSGQAVTVSRQPSLNAYNSLTRSGLKRTPSLKPDVPPKPSFAPLSTSMKPNDACT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35464-1", "uniprot_id": "SEM6A_MOUSE", "id": "O35464-1", "name": "Semaphorin-6A", "aln": "-----------------------------------------------------------MRPAALLLCLTLLHCAGAGFPEDSE---------PISISHGNYTKQYPVFVGHKPGRNTTQRHRLDIQMIMIMN-RTLYVAARDHIYTVDIDTSHTEEIYCSKKLTWKSRQADVDTCRMKG-KHKDECHNFIKVLLKKND--DTLFVCGTNAFNPSCRNYRVDTLETFGDEFS-----GMARCPYDAKHANIALFADG-------KLYSATVTDFLAIDAVIYR--------SLGDSPTLRTVKHDSKWLKEPYFVQAVDYGDYIYFFFREIAVEYNTMGKVVFPRVAQVCKNDMGGSQRVLEKQWTSFLKARLNCSVPGDSHFYFNILQAVTDVIR----INGRDVVLATFSTPYNSIPGSAVCAYDMLDIANVFTGRFKEQKSPDSTWTPVPDERVPKPRPGCCAGSSSLEKYATSNEFPDDTLNFIKTHPLMDEAVPSIINRPWFLRTMVRYRLTKIAVDNAAGPY--QNHTVVFLGSEKGIILKFLARIGSSGFLNGSLFLEEMNVYNPEKCSYDGVEDKRIMGMQLDRAS----GSLYVAFSTCVIKVPLGRCER-HGKCKKTCIASRDPYCGWVRESGSCAHLSPLSRLTFEQDIERGNTDGLGDCHNSFVALNGHASSLYPSTTTSDSASRDGYESRGGMLDWNDLLEAPGSTDPLGAVSSHNHQDKKGVIRESYLKSNDQLVPVTLLAIAVILAFVMGAVFSGIIVYCVCDHRRKDVAVVQRKEKELTHSRRGSMSSVTKLSGLFGDTQSKDPKPEAILTPLMHNGKLATPSNTAKMLIKADQHHLDLT--ALPTPESTPTLQQKRKPNRGSREWERNQNIINACTKDMPPMGSPVIPTDLPLRASPSHIPSVVVLPITQQGYQHEYVDQPKMSEVVAQMALEDQAATLEYKTIKEHLSSKSPNHGVNLVENLDSLPPKVPQREASLGPPGTSLSQTGLSKRLEMQHSSSYGLEYKRSYPTNSLTRSHQTTTLKRNNTNSSNSSHLSRNQSFGRGDNPPPAPQRVDSIQVHSSQPSGQAVTVSRQPSLNAYNSLTRSGLKRTPSLKPDVPPKPSFAPLSTSMKPNDACT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H2E6-1", "uniprot_id": "SEM6A_HUMAN", "id": "Q9H2E6-1", "name": "Semaphorin-6A", "aln": "-----------------------------------------------------------MRSEALLLYFTLLHFAGAGFPEDSE---------PISISHGNYTKQYPVFVGHKPGRNTTQRHRLDIQMIMIMN-GTLYIAARDHIYTVDIDTSHTEEIYCSKKLTWKSRQADVDTCRMKG-KHKDECHNFIKVLLKKND--DALFVCGTNAFNPSCRNYKMDTLEPFGDEFS-----GMARCPYDAKHANVALFADG-------KLYSATVTDFLAIDAVIYR--------SLGESPTLRTVKHDSKWLKEPYFVQAVDYGDYIYFFFREIAVEYNTMGKVVFPRVAQVCKNDMGGSQRVLEKQWTSFLKARLNCSVPGDSHFYFNILQAVTDVIR----INGRDVVLATFSTPYNSIPGSAVCAYDMLDIASVFTGRFKEQKSPDSTWTPVPDERVPKPRPGCCAGSSSLERYATSNEFPDDTLNFIKTHPLMDEAVPSIFNRPWFLRTMVRYRLTKIAVDTAAGPY--QNHTVVFLGSEKGIILKFLARIGNSGFLNDSLFLEEMSVYNSEKCSYDGVEDKRIMGMQLDRAS----SSLYVAFSTCVIKVPLGRCER-HGKCKKTCIASRDPYCGWIKEGGACSHLSPNSRLTFEQDIERGNTDGLGDCHNSFVALNGHSSSLLPSTTTSDSTAQEGYESRGGMLDWKHLLDSPDSTDPLGAVSSHNHQDKKGVIRESYLKGHDQLVPVTLLAIAVILAFVMGAVFSGITVYCVCDHRRKDVAVVQRKEKELTHSRRGSMSSVTKLSGLFGDTQSKDPKPEAILTPLMHNGKLATPGNTAKMLIKADQHHLDLT--ALPTPESTPTLQQKRKPSRGSREWERNQNLINACTKDMPPMGSPVIPTDLPLRASPSHIPSVVVLPITQQGYQHEYVDQPKMSEV-AQMALEDQAATLEYKTIKEHLSSKSPNHGVNLVENLDSLPPKVPQREASLGPPGASLSQTGLSKRLEMHHSSSYGVDYKRSYPTNSLTRSHQATTLKRNNTNSSNSSHLSRNQSFGRGDNPPPAPQRVDSIQVHSSQPSGQAVTVSRQPSLNAYNSLTRSGLKRTPSLKPDVPPKPSFAPLSTSMKPNDACT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q24323-1", "uniprot_id": "SEM2A_DROME", "id": "Q24323-1", "name": "Semaphorin-2A", "aln": "--------------------------------------------------------MSLLQLSPLLALLLLLCSSVSETAADYENTWNFYYERPCCTGNDQGNNNYGKHGADHVREFNCGKLYYRTFHMNEDR-DTLYVGAMDRVFRVNLQN-ISSSNCNRDVINLEPTRDDVVSCVSKGKSQIFDCKNHVRVIQSMDQ-GDRLYVCGTNAHNPKDYVIYANLTHLPRSEYVIGVGLGIAKCPYDPLDNSTAIYVENGNPGGLPGLYSGTNAEFTKADTVIFRTDLYNTSAKRLEYKFKRTLKYDSKWLDKPNFVGSFDIGEYVYFFFRETAVEYINCGKAVYSRIARVCKKDVGG-KNLLAHNWATYLKARLNCSISGEFPFYFNEIQSVYQLPS----DKSR--FFATFTTSTNGLIGSAVCSFHINEIQAAFNGKFKEQSSSNSAWLPVLNSRVPEPRPGTCVN--------DTSNLPDTVLNFIRSHPLMDKAVNHEHNNPVYYKRDLVFTKLVVDKIRIDILN--QEYIVYYVGTNLGRIYKIVQYYRNGESLSKLLDIFEVAPN------------EAIQVMEISQTR----KSLYIGTDHRIKQIDLAMCNR-RYDNCFRCVR--DPYCGWDKEANTCRPY----ELDLLQDVANETSD-------------------------------------------------------------------------------------------------------------ICDSS------VLKKKIVVTYGQSVHLGCFVKIPEVLKNEQ----------VTWYHHSKDKG---------RYEIRYSPTK--YIETTERGLVVVSVNEADGGRYDCHLGGSLLCSYNITVDAH-----------RCTP---------PNKSNDYQKIYS---------------------------------------------------------------------------------DWCHEFEKYKTAMKSWEKKQAQCSTRQN---FSSN-QHPNEIFRKPNV------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A0B4KG38-1", "uniprot_id": "A0A0B4KG38_DROME", "id": "A0A0B4KG38-1", "name": "Semaphorin-2A", "aln": "MPLNAQLKIAQSVNKVTYAKVSDSNCCAKKQQKYSIADFSQAKRQAGSMCATGKGKHRLCSLSALLLVLVAQTVHVEYARADYENTWNLYYEPPCCTG--SSAAHHLRHHKEHVQDFSCGPLHYKTFYMDERN-NALYVGAMDRIFRLNLRN-ISQSICERDVLILEPTGSDILNCVSKGKREKVECRNHIRVIQPMNFNGQKLYVCGTNAHNPKDYVINANLTHLPRSQYVPGIGLGIGKCPYDPADNSTAVYVENGNPFGLPALYAGTNAEFTKADSVIFRSDLYNLTNGRKEANFKRTVKYDSKLLDKPNFVGSFEIGEFVYFFFREHAVEYINCGKAVYSRVARVCKNDRGG-KYMISQNWATYLKARMNCSISSEFPFYFNEIQSVYKMPT----DDTK--FYATFTTNTNGLIGSAVCSYDIRDINAAFDGKFKEQATSNSAWLPVLNSKVPEPRPGTCHN--------DTATLPDSVLNFIRKHPLMDKAVDHEFGNPVFFKRDVILTKLVVDKIRIDKLN--QEFLVYFVATTSGHIYKIVQFMHYGQRHSNLVDIFEASPHS-----------EPIREMTLSHKT----GSLYVATDHQVKQIDIAMCAR-RYDSCFRCVS--DPYCGWDKDVNACRPY----QLGLLQDVANETSG-------------------------------------------------------------------------------------------------------------ICDTS------VLRKKVTSSYGQTLHLSCFVKMPEVLRKKQ----------TRWYHHSTEKG---------RYEVRYTPTK--YIDTNEGGLVLLAVNEGDGGRYDSYLDGTLLCSYGVTVDAH-----------RCSP---------PSQKQDYQKIYS---------------------------------------------------------------------------------HWCNEFEKYKSAMKQWQAKQEQCGLKDKTGPISSNGKHVNDVFSNDALVX--PRKYLYSFEFLSSATEGVASAHRKLYIFVFVLTIFARF------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q24322-1", "uniprot_id": "SEM1A_DROME", "id": "Q24322-1", "name": "Semaphorin-1A", "aln": "------------------------------MLNSHNTNHNNNSASNSNYNKGHKMHLKSATAKATIMKHKLSKFYGYGWMQVFLLLTVLVIGNQSAWQENIRPKLYVELGPEDVLKFVGNESVVDHFKLVTKDGNSLLIGARNTVFNLSIHDLVEQQ-----RLVWTSPEDDTKMCLVKG-KDEEACQNYIRIMVVPSP--GRLFVCGTNSFRPMCNTYIISDSNYTLEATKN----GQAVCPYDPRHNSTSVLADN-------ELYSGTVADFSGSDPIIYR-------------EPLQTEQYDSLSLNAPNFVSSFTQGDFVYFFFRETAVEFINCGKAIYSRVARVCKWDKGG-PHRFRNRWTSFLKSRLNCSIPGDYPFYFNEIQSASNLVEGQYGSMSSKLIYGVFNTPSNSIPGSAVCAFALQDIADTFEGQFKEQTGINSNWLPVNNAKVPDPRPGSCHN--------DSRALPDPTLNFIKTHSLMDENVPAFFSQPILVRTSTIYRFTQIAVDAQIKTPGGKTYDVIFVGTDHGKIIKSVNAESADSADKVTSVVIEEIDVLTKSEPIRNLEIVRTMQYDQPKDGSYDDGKLIIVTDSQVVAIQLHRCHNDKITSCSECVALQDPYCAWDKIAGKCRSHGAPRWLEENYFYQNVATGQHAACPSGKINSKDANAGEQKGFRN---------------------------------------------------------------------------------DMDLLDSRRQSKDQEIIDNIDKNFEDIINAQYTVETLVMAVLAGSIFSLLVGFFTGYFCGRRCHKDEDDNLPYPDTEYEYFEQRQNVNSFPSSCRIQQEPKLLPQVEEVTYAEPVLLPQPPPPNKMHSPKNTLRKPPMHQMHQGPNSETLFQFQPDGYNTQQSYR------------------------------------------------------------------------------GRDNFGTLRSHQVMGDNYRRGDGFSTTRSVKKAVNNTNTRNRSLGRARRQPPRHGIVTQHRSNSPQQQQQQSQQPHSSSGSSPVMSNSSSSPAPPSSSPSPQESPKNCSYIYRD-------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . : .. : :* :.* : :: :.: .. : . * * ** . *:*.:::: . *:*****:..* . . . * . ****. . . :: .:. **:.* ::* *.:*:* :* ::** *. * ** :. *:::****** ***: . **.::.*:*:*** * ** : :.*:::**:*:***:..: **** :*:. .: . ..*.* *.: *****:: : :* .* *:**** :* * ** : :**.**** * . : :** .****:.*.***: * ..* : : : . * ::.: * * * : . . : * : .* : . : : : * . : *: ****.* : . * * . :. : * .: .. .: : . : .: . . :: : :.*: : . : . .. * : . ", "identical_positions": 122, "similar_positions": 167, "identity": "10.74%" }, { "cls_id": "homologset.agr.MGI:1203728", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P84060-1", "uniprot_id": "DTNB_RAT", "id": "P84060-1", "name": "Dystrobrevin beta", "aln": "MIEEGGNKRKTMAEKRQLFIEMRAQNFDVIRLSTYRTACKLRFVQKRCNLHLVDIWNMIEAFRDNGLNTLDHATEISVSRLETVISSIYYQLNKRLPSTHQINVEQSISLLLNFMIAAYDSEGRGKLTVFSVKAMLATMCGGKMLDKLRYIFSQMSDSNGLMMFGKLDQFLKEALKLPTAVFEGPSFGYTEHAVRTCFPQQKKIMLNMFLDTMMADPPPQCLVWLPLMHRLAHVENVFHPVECSYCHCESMMGFRYRCQQCHNYQLCQNCFWRGHAGGPHSNQHQMKELSSWKSPAKKLSHAISKSLGCVPSR-EPPHPVFPEQPEKPLDLAHIVPPRPLTN-MNDTMVSHMSSGVPTPTKRLQYGQDMPNLLADEHALIA-----SYVARLQHCTRVLDSPSRLDEEHRLIARYAARLAAEAGNMTR-PPTDASFNFDANKQQRQLIAELENKNREILQEIQRLRLEHEQASQPTPEKAQQNPTLLAELRLLRQRKDELEQRMSALQESRRELMVQLEGLMKLLK-------AQATGSPHTSPTHGGGRSMP-----------------------MP--VRSTSAG-------STPTHGPQ-----DSLSGVGGDVQEAFA------------------------------QGTRRNLRNDLLVAADSITNTMSSLVKELHSGE----------------------------TQRFPLVSSSPSCPLP----------------CPTIPTHSPSFHATFPSRNTRDLHPVPPSHMVSLY-----------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70585-1", "uniprot_id": "DTNB_MOUSE", "id": "O70585-1", "name": "Dystrobrevin beta", "aln": "MIEEGGNKRKTMAEKRQLFIEMRAQNFDVIRLSTYRTACKLRFVQKRCNLHLVDIWNMIEAFRDNGLNTLDHSTEISVSRLETVISSIYYQLNKRLPSTHQISVEQSISLLLNFMVAAYDSEGRGKLTVFSVKAMLATMCGGKMLDKLRYIFSQMSDSNGLMMFGKLDQFLKEALKLPTAVFEGPSFGYTEHAVRTCFPQQKKIMLNMFLDTMMADPPPQCLVWLPLMHRLAHVENVFHPVECSYCHCESMMGFRYRCQQCHNYQLCQNCFWRGHASGAHSNQHQMKEHSSWKSPAKKLSHAISKSLGCVPSR-EPPHPVFPEQPEKPLDLAHLVPPRPLTN-MNDTVVSHMSSGVPTPTKRLQYSQDMPNLLADEHALIA-----SYVARLQHCTRVLDSPSRLDEEHRLIARYAARLAAEAGNMTR-PPTDASFNFDANKQQRQLIAELENKNREILQEIQRLRLEHEQASQPTPEKAQQNPMLLAELRLLRQRKDELEQRMSALQESRRELMVQLEGLMKLLK-------AQATGSPHTSPTHGGGRPMP-----------------------MP--VRSTSAG-------STPTHGPQ-----DSLSGVGGDVQEAFA------------------------------QGTRRNLRNDLLVAADSITNTMSSLVKELHSGA----------------------------EAEEQAGTEKTREGLPPR-----------GTFLSVFLLHTWTKLAGCQTHSTSRERSQAYGKWGGTA-----------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60941-1", "uniprot_id": "DTNB_HUMAN", "id": "O60941-1", "name": "Dystrobrevin beta", "aln": "MIEESGNKRKTMAEKRQLFIEMRAQNFDVIRLSTYRTACKLRFVQKRCNLHLVDIWNMIEAFRDNGLNTLDHTTEISVSRLETVISSIYYQLNKRLPSTHQISVEQSISLLLNFMIAAYDSEGRGKLTVFSVKAMLATMCGGKMLDKLRYVFSQMSDSNGLMIFSKFDQFLKEVLKLPTAVFEGPSFGYTEHSVRTCFPQQRKIMLNMFLDTMMADPPPQCLVWLPLMHRLAHVENVFHPVECSYCRCESMMGFRYRCQQCHNYQLCQNCFWRGHAGGPHSNQHQMKEHSSWKSPAKKLSHAISKSLGCVPTR-EPPHPVFPEQPEKPLDLAHIVPPRPLTN-MNDTMVSHMSSGVPTPTKRLQYSQDIPSHLADEHALIA-----SYVARLQHCARVLDSPSRLDEEHRLIARYAARLAAEAGNVTR-PPTDLSFNFDANKQQRQLIAELENKNREILQEIQRLRLEHEQASQPTPEKAQQNPTLLAELRLLRQRKDELEQRMSALQESRRELMVQLEELMKLLKEEEQKQAAQATGSPHTSPTHGGGRPMP-----------------------MP--VRSTSAG-------STPTHCPQ-----DSLSGVGGDVQEAFA------------------------------QGTRRNLRNDLLVAADSITNTMSSLVKELHSAE----------------------------EGAEEEEEK-------------------------------------MQNGKDRG------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PE99-1", "uniprot_id": "A0A8M9PE99_DANRE", "id": "A0A8M9PE99-1", "name": "Dystrobrevin", "aln": "MIEEGSKSSKSMVEKRQLFMEMRAQNFDVIRLSTYRTACKLRFVQKRCNLHLVDVWNMIEAFRDNGLSTLDHNAEINVSRLETILSSIFYQLNKRLPTTHQINVEQSIGLLLNFIVATYDSEGHGKLTVFAMKAMLATMCGGKILDKLRYVFSQISDSNGVMVFAKFDQFLREVLKLPTAVFEGPSFGYTEHSVRTCFPQQKKILLNTFLDVLMADPPPQCLVWLPLMHRLANVENVFHPVECSYCRSESMMGFRYRCQQCHGYQLCQSCFWRGHASGPHSNQHQMKEHSSWKSPAKKLSHAISKSLGCMPIG-EPPHPVFPEAAERPQDLAHTTQLRPLADNMSDTVL--ISSGTPTPSK-----------------------------------STLESPSRLDEEHRLIARYAARLAAEASNSTQCPPSDLSFNFDANKQQRQLIAELENKNREILQEIQRLRLEHEQASQPTPEKAQQNPTLLAELRLLRHRKDELERRMSALQESRRELMVQLEGLMRLLKDEEQKQAAQTGTSPHSSPSHSASCTMP-----------------------MP--IRSTSAG-------STPTHTPQ-----DCLAGVGDDVLDAFS------------------------------QGVPRNLRNDLLVAADSITNTMSSLVKELHSVD----------------------------DGLEEEEENMRNGREK------------------------------MSSLKHSGKRHSTPSF----------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M2BFU1-1", "uniprot_id": "A0A8M2BFU1_DANRE", "id": "A0A8M2BFU1-1", "name": "Dystrobrevin", "aln": "MIEEG-RKAGVMADRKQLFMDMKTQNYDTIRLSTYRTACKLRFVQKKCNLHLVDVWNMIEAFRDNGLNTLDVCTEISVARLETILTCIYQQLNKRLPTTHQISVQHNTSLLLNFMATAHDTDAQGRLTVFSVKMMLSVLCGGKLVDKLRYIFSQISDSHGAMEMSKFDHFLREALKLPAAVFEGPSFGYLDHLARSCFPQQKKVMLNMFLDALMSDPPPQCLIWLPLVHRMGNVENVHHPVSCSFCRSDGMTGFRYRCQQCFNYQLCQNCFWRGHASGNHSNHHDMKEHSSWKSPAKKLGRAISKSLGCVPSR-EPSHPIYPEYPEKPLNLSNIVPPRPIGN-MNEPAPP-LSTGS-SPTKRLP-TLAAAQRMNEEHALIA-----AYVNKLQSSPRALDSPVRSDEEHKLIARYASRLATDPGHTAR----PADFSYDTNKQQRELIMQLENKNREILQEIQRLRVEHEQACQPTPERVQQNPTLLAELRQLRQRKDELEQRMSSLQESRRELMVQLEGLMKLLKDEEQRQAAQAAGS---SPSHASPRSMP-----------------------MP--IRSPSSGPAPTYTGHTPTHGPQ-----DSLAGVGGDVQEAFS------------------------------QGPRRNLRNDLLVAADSITNTMSSLVKELNSAE----------------------------DGDEDERLLQ--------------------------------------NGKDRG------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A8DYB7-1", "uniprot_id": "A8DYB7_DROME", "id": "A8DYB7-1", "name": "", "aln": "---------MELEPRVAILQDLRLQTFDSIRFASYRTASKLRYIQKSTNLHLVDIWNVIEAFRENGLNTLEPQSEVSVARLETLVSSLYHNLNKRLPTAQQVPVDSKAGLLLNWLLAAYTSDNSGKIRVFSIKVALATMCSGKLVDKLRYIFSQISDGAGQLVAWKLGEFLREVLALPAAVYESPTFHYKEGLEEEIFPAENKVTVNDFMATLMSEPGPSCLVWLPLVHRLATVETIVHPTVCSVCHKENFTGFRYRCQRCHAYQLCQECFWHGKTSLNHQNDHEVKEYSSYKSPSKQIGHSLRKSFRCVPEKTVQVLPRFPDQPEKTLNLSHIVPPSPLPSHNGFSDPSGLVHGHHGPHPGLPGQHGLFDRSSTLDSRATGRSLDSASGTAGTTMSRVAAASANDEEHRLIARYAARLAQENRAPSNLPDNATPIGTDNSRAQRELIAQLESKNKEIMREIARLRRQQE-----TEQMAPENPALINELRALRQRKGELEGHLGALQDSRRQLMEQLEGLMRMLKNQ---QTASPRSTPNSSPRSGKSPPMPGGAGILGTSPMSALHAQQMQQHPMAGGVRASQQQLLQQQQQQAHGHGPFSQSQLEQLNQISSDMRSAFAANGSATPPPMRTTTATANVSAIPSLNPISNQNPNLNPDAELNEAADHLTSAISHMVSDLNAGRGRAQQLGPQPASSIPQARFIMPLEFRHIEGGESEDSSQCECNDCECGEYEEVFRTDEDLECEGAAAPFGNAYSLFPTSGVHEEDHFDYTFGQGEELSQVNRILGYRNHPELFIDDEQAGFPALHEIGETIDELQLIMHAYIMKYSLNI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :: ::: *.:* **:::****.***::** ******:**:*****:***.**: :*:.*:****:::.:: :******:::*: *: . .****:: ::: :: *:: **::* *:.:*.**::*****:***:**. * : *:..**:*.* **:**:*.*:* * : . ** :.*: :* *: .:*::* *.**:****:**:. **.: **. ** *: :.: *******:*. *****.***:*::. *.*.*::** **:***:*::.::: **: *:* * :*: .*:. :*:: . *: . . . : * * : :. ****:******:*** : :. :. * .: **:** :**.**:**::** *** ::* * : . :** *: *** **:**.*** ::.:**:***:** *** **::** *.. : ** . .** *. :*:.. : * * : * :..*: .**: *. * :* *** :*.::* :*.:*:: . ", "identical_positions": 224, "similar_positions": 190, "identity": "26.89%" }, { "cls_id": "homologset.agr.MGI:1203729", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZTF6-1", "uniprot_id": "D3ZTF6_RAT", "id": "D3ZTF6-1", "name": "Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha", "aln": "MAQISNNSEFKQCSSSHPEPIRTKDVD-KAEALQMEAEALAKLQKDRHMTDSPRGFELSNSTRQRTQGFN-KQDYDLMVFPESDSQKR-----ALDIDVEKLTQAELEKILLDDNFETRKT--PASPVTPVLSPSFSAQLYLRPAVQRSQWPPGLCGPSTYTLPSIYPSA-YSK-QATFQNGFSPRMPTFPSTESIYLRLPGQSPYFSYPLTPATPFHPQGSLPVYRPLVSPDMAKLFDKIASTSEFLKNGKARTDLEIANSKASVCNLQISPKSEDINKFDWLDLDPLSKPKIDCVEVLEHEEEK--KNPVLLAEDPWDAVLLEERSPT---SRHLERKVNG----KSLSGATVTRSQSLIVRTTQVTKAQSQVSQKDPNGTSSLATGSSLLQEFEVQNEEVAAFCQSIMKLKTKFPYTDHCTNPGYLLSPVTVQRNMCGEN-ASVKVSIEIEGFQQPVTFTCDVSSTVDIIIMQALCWVHDDLNQVDVGSYILKVCGQEEVLQNNHCLGSHEHIQNCRKWDTEIKLQLLTFSAMCQNLARTAEDDEAPVDLNKYLYQIEKPYKEVMTRHPVEELLDSYHYQVELALQTEN-QHRAIDQVIKAVRKICSALDGVETPAVTEAVKKLKRAVNLPRNKSADVTSLSGG-DTSKNSTRGSLNLENPVQVSMDHLTAAIYDLLRLHTNSCKSST------VCPQGSRNIKEAWTATEQLQFTVYAAHGISSNWVSNYEKYYLICSLSHNGKDLFKPIQSKKVGTYKNFFYLIKWDELIIFPIQISQLPLESVLHLTLFGVLNQSSGSSPDSNKQRKGPEALGKVSLTLFDFKRFLTCGTKLLYLWTSSHTNSIPGAIPQKSYVMERIVLQVDFPSPAFDIIYTSPQIDRNIIQQYKLEALENEIKGKLLDIVHRDSSFGLSKEDKAFLWEKRYYCLKHPNCLPKILASAPNWKWANLAKTYSLLHQWPPLCPLAALELLDAKFADQEVRSLAVSWIEAISDDELTDLLPQFVQALKYEIYLNSSLVRFLLSRALGNIQIAHSLYWLLKDALHDTRFGSRYEHVLGALLSVGGKGLREELSKQMKLVQLLGGVAEKVRQASGSARQVVLQKSMERVQSFFLRNKCRVPLKPSLVAKELNIKSCSFFSSNAMPLKVTMVNADPLGEEINVMFKVGEDLRQDMLALQMIKIMDKIWLKEGLDLRMVIFKCLSTGRDQGMVELVPASDTLRKIQVEYGVTGSFKDKPLAEWLRKYNPSEEEYEKASENFIYSCAGCCVATYVLGICDRHNDNIMLRSTGHMFHIDFGKFLGHAQMFGSFKRDRAPFVLTSDMAYVINGGEKPTIRFQLFVDLCCQAYNLIRKQTNLFLNLLSLMIPSGLPELTSIQDLKYVRDALQPQTTDAEATIFFTRLIESSLGSIATKFNFFIHNLAQLRFSGLPSNDEPILSFSPKTYSFRQDGRIKEVSVFTYHKKYNPDKHYIYVVRILREGHLEPSFVFRTFDEFQELHNKLSIIFPLWKLPGFPNRMVLGRTHIKDVAAKRKIELNSYLQSLMNASTDVAECDLVCTFFHPLLRDEKAEG---IARSTGTSPFSPTLGQIGGAVKLSVSYRNGTLFIMVMHIKDLVTEDGADPNPYVKTYLLPDTHKTSKRKTKISRKTRNPTFNEMLVYSGYSRETLRQRELQLSVLSAESLRENFFLGGITLPLKDFNLSKETVKWYQLTAATYL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61194-1", "uniprot_id": "P3C2A_MOUSE", "id": "Q61194-1", "name": "Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha", "aln": "MAQISNNSEFKQCSSSHPEPIRTKDVN-KAEALQMEAEALAKLQKDRQMTDSPRGFELSSSTRQRTQGFN-KQDYDLMVFPELDSQKR-----AVDIDVEKLTQAELEKILLDDNFETRKP--PALPVTPVLSPSFSTQLYLRPSGQRGQWPPGLCGPSTYTLPSTYPSA-YSK-QATFQNGFSPRMPTFPSTESVYLRLPGQSPYFSYPLTPATPFHPQGSLPVYRPLVSPDMAKLFEKIASTSEFLKNGKARTDLEIANSKASVCNLQISPKSEDINKFDWLDLDPLSKPKVDYVEVLEHEEEK--KDPVLLAEDPWDAVLLEERSP----SCHLERKVNG----KSLSGATVTRSQSLIIRTAQFTKAQGQVSQKDPNGTSSLPTGSSLLQEFEVQNDEVAAFCQSIMKLKTKFPYTDHCTNPGYLLSPVTVQRNMCGEN-ASVKVSIEIEGLQLPVTFTCDVSSTVEIIIMQALCWVHDDLNQVDVGSYILKVCGQEEVLQNNHCLGSHEHIQNCRKWDTEIKLQLLTLSAMCQNLARTAEDDEAPVDLNKYLYQIEKPYKEVMTRHPVEELLDSYHYQVELALQTEN-QHRAVDQVIKAVRKICSALDGVETPSVTEAVKKLKRAVNLPRNKSADVTSLSGS-DTRKNSTKGSLNPENPVQVSMDHLTTAIYDLLRLHANSSRCST------ACPRGSRNIKEAWTATEQLQFTVYAAHGISSNWVSNYEKYYLICSLSHNGKDLFKPIQSKKVGTYKNFFYLIKWDELIIFPIQISQLPLESVLHLTLFGVLNQSSGSSPDSNKQRKGPEALGKVSLTLFDFKRFLTCGTKLLYLWTSSHTNSIPGAIPKKSYVMERIVLQVDFPSPAFDIIYTSPQIDRNIIQQDKLETLESDIKGKLLDIIHRDSSFGLSKEDKVFLWENRYYCLKHPNCLPKILASAPNWKWANLAKTYSLLHQWPPLCPLAALELLDAKFADQEVRSLAVSWMEAISDDELADLLPQFVQALKYEIYLNSSLVRFLLSRALGNIQIAHSLYWLLKDALHDTHFGSRYEHVLGALLSVGGKGLREELSKQMKLVQLLGGVAEKVRQASGSTRQVVLQKSMERVQSFFLRNKCRLPLKPSLVAKELNIKSCSFFSSNAMPLKVTMVNADPLGEEINVMFKVGEDLRQDMLALQMIKIMDKIWLKEGLDLRMVIFRCLSTGRDRGMVELVPASDTLRKIQVEYGVTGSFKDKPLAEWLRKYNPSEEEYEKASENFIYSCAGCCVATYVLGICDRHNDNIMLRSTGHMFHIDFGKFLGHAQMFGSFKRDRAPFVLTSDMAYVINGGEKPTIRFQLFVDLCCQAYNLIRKQTNLFLNLLSLMIPSGLPELTSIQDLKYVRDALQPQTTDAEATIFFTRLIESSLGSIATKFNFFIHNLAQLRFSGLPSNDEPILSFSPKTYSFRQDGRIKEVSVFTYHKKYNPDKHYIYVVRILREGHLEPSFVFRTFDEFQELHNKLSIIFPLWKLPGFPNRMVLGRTHIKDVAAKRKIELNSYLQSLMNASTDVAECDLVCTFFHPLLRDEKAEG---IARSAGAVPFSPTLGQIGGAVKLSVSYRNGTLFIMVMHIKDLVTEDGADPNPYVKTYLLPDTHKTSKRKTKISRKTRNPTFNEMLVYSGYSKETLRQRELQLSVLSAESLRENFFLGGITLPLKDFNLSKETVKWYQLTAATYL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00443-1", "uniprot_id": "P3C2A_HUMAN", "id": "O00443-1", "name": "Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha", "aln": "MAQISSNSGFKECPSSHPEPTRAKDVD-KEEALQMEAEALAKLQKDRQVTDNQRGFELSSSTRKKAQVYN-KQDYDLMVFPESDSQKR-----ALDIDVEKLTQAELEKLLLDDSFETKKT--PVLPVTPILSPSFSAQLYFRPTIQRGQWPPGLPGPSTYALPSIYPST-YSK-QAAFQNGFNPRMPTFPSTEPIYLSLPGQSPYFSYPLTPATPFHPQGSLPIYRPVVSTDMAKLFDKIASTSEFLKNGKARTDLEITDSKVS--NLQVSPKSEDISKFDWLDLDPLSKPKVDNVEVLDHEEEK--NVSSLLAKDPWDAVLLEERSTA---NCHLERKVNG----KSLSVATVTRSQSLNIRTTQLAKAQGHISQKDPNGTSSLPTGSSLLQEVEVQNEEMAAFCRSITKLKTKFPYTNHRTNPGYLLSPVTAQRNICGEN-ASVKVSIDIEGFQLPVTFTCDVSSTVEIIIMQALCWVHDDLNQVDVGSYVLKVCGQEEVLQNNHCLGSHEHIQNCRKWDTEIRLQLLTFSAMCQNLARTAEDDETPVDLNKHLYQIEKPCKEAMTRHPVEELLDSYHNQVELALQIEN-QHRAVDQVIKAVRKICSALDGVETLAITESVKKLKRAVNLPRSKTADVTSLFGGEDTSRSSTRGSLNPENPVQVSINQLTAAIYDLLRLHANSGRSPT------DCAQSSKSVKEAWTTTEQLQFTIFAAHGISSNWVSNYEKYYLICSLSHNGKDLFKPIQSKKVGTYKNFFYLIKWDELIIFPIQISQLPLESVLHLTLFGILNQSSGSSPDSNKQRKGPEALGKVSLPLFDFKRFLTCGTKLLYLWTSSHTNSVPGTVTKKGYVMERIVLQVDFPSPAFDIIYTTPQVDRSIIQQHNLETLENDIKGKLLDILHKDSSLGLSKEDKAFLWEKRYYCFKHPNCLPKILASAPNWKWVNLAKTYSLLHQWPALYPLIALELLDSKFADQEVRSLAVTWIEAISDDELTDLLPQFVQALKYEIYLNSSLVQFLLSRALGNIQIAHNLYWLLKDALHDVQFSTRYEHVLGALLSVGGKRLREELLKQTKLVQLLGGVAEKVRQASGSARQVVLQRSMERVQSFFQKNKCRLPLKPSLVAKELNIKSCSFFSSNAVPLKVTMVNADPMGEEINVMFKVGEDLRQDMLALQMIKIMDKIWLKEGLDLRMVIFKCLSTGRDRGMVELVPASDTLRKIQVEYGVTGSFKDKPLAEWLRKYNPSEEEYEKASENFIYSCAGCCVATYVLGICDRHNDNIMLRSTGHMFHIDFGKFLGHAQMFGSFKRDRAPFVLTSDMAYVINGGEKPTIRFQLFVDLCCQAYNLIRKQTNLFLNLLSLMIPSGLPELTSIQDLKYVRDALQPQTTDAEATIFFTRLIESSLGSIATKFNFFIHNLAQLRFSGLPSNDEPILSFSPKTYSFRQDGRIKEVSVFTYHKKYNPDKHYIYVVRILREGQIEPSFVFRTFDEFQELHNKLSIIFPLWKLPGFPNRMVLGRTHIKDVAAKRKIELNSYLQSLMNASTDVAECDLVCTFFHPLLRDEKAEG---IARSADAGSFSPTPGQIGGAVKLSISYRNGTLFIMVMHIKDLVTEDGADPNPYVKTYLLPDNHKTSKRKTKISRKTRNPTFNEMLVYSGYSKETLRQRELQLSVLSAESLRENFFLGGVTLPLKDFNLSKETVKWYQLTAATYL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F6NMW9-1", "uniprot_id": "F6NMW9_DANRE", "id": "F6NMW9-1", "name": "Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha", "aln": "MAHISSGNGFKFDRPASPGVVRPKGIVGKEEALRMEVEAFDKIKREKRHTLPVTASSVNPLPNPTAQTSSSRPEKDLIVFCESETQKKEQKDNFEDIDLENLTKEELEKLLLDDSFGANKMTRPSSLLGCNLSASYPGGHAFNPS--SFHWTP----TPTHAQTPIFPSAPFAKPPCSFQNGFSPAMSPFIP----------PTPFLSF-----TPIQPPAALVYSQPAVTPEMAKLFDKIASTSEYLKNGRSSSMETESASVKSLEPLPLPSEPPNISRFEWLDLDPLNKRKEVEVEETPAVSSCPFIEESGKAKDPWDAVLQDEHETVDNGSPTAEEKSKATQPRRASTGAAVTKSQSLSISANSTNQSTGKQVNK---GSTNVLSKYSALQEKEAQNLEVVAFCEDISKLRSKFPHDDLSTNPGYVLSPVITQRDAGGDNGGSVKVSIEISDSQQPVTFTCDVTSPVDLLIMQALCWVHDDLNQVDINSYVLKVCGQEEVLQNKHSLGSHEYVQNCRKWESEIKLQLLFLSTMRRDLARTAEDDISPIDLEKYLGLVERPFKEAVTREGLAEYLEGFHKQVNLCLQNENNQYKTVDNVVQSVKNLCCALDEVETPAITDAVKRLKRSVNLPRTRSPEAGATSSG-----GSANG---YSSPVEESLAVLTDAVYELAKLYLQSFCPISPGFMIEEHKEDERDSKEASGTTEHLQFTLFAVHGIPATWVSSFEKYYLMCALTHNNRNLFKPVQSKKVGTYKSFFYHIKWDELINFPISVSLLPLEAMLSLSLYGVLSQNANNSPDSNKQRKGPELLGKVSMPLFDFRRVLSRGSKLLSLWTSPQA-LQPGAAGKGRNPTEKIILQVDFPSPAVDVLYVGPQENGCPNPQ-SLDPLDQDDRSEIEKLCARASTFGLSRADRQLLWDQRYYCREYEYSLPKILASAPSWDWGSMGEIHALLHHWPALSPVSALELLESKFADTEVRKVAVSWIQSSSDDELADYLPQLVQAVKFECHLNNALVKFLLSRALGNVNIAHYLYWLLRDAVQDPAFGQRYERILCVLLCLCGTGLRAELEKQTRLVQLLGALAEKVRQASSSTRQVVLLEGLERVQSFFQKNSCRLPISPSLVAKELNIKVCSFFNSNAVPLKIALVNADPLGDEINVMFKVGEDLRQDMLALQMIRIMDRIWLQEGLDLRIVNFKCISTGKDKGMVELVPSSETLRKIQVEYGVTGSFKDKPLAEWLRKYNPAEDEYEKASENFIYTCAGCCVATYILGICDRHNDNIMLRSTGHMFHIDFGKFLGHAQMIGSFKRDRAPFVLTSDMAYVINGGERPTSRFQLFVDLCSQAYNLIRKHSNLFLNLLSLMTQSGLPELTGVQDLKYVYDALQPQTTDAEATIFFTRLIESSLGSVATKFNFFIHNLAQLRFSGLPSNDEPILSFAPRTYTMKQDGKIRDASVFSFQKRYNPDKHYTYVIRILREGQSEPQFVFRTFDEFQELHNKLTILFQLWKLPGFPSKMVLGRTHIKDVASKRKVELNSYVHNLMRSSTEVAQCDLIYTFFHPIARDDKTEGVDTLSKTPDMPPVSPTTGRVEGEVKLSVSYRNSTLFIMVMHIKDLMSNDGADPNPYVKTYLLPDPHKTSKRKTKIARKTRNPTFNEMLVYSGYSKETLKQRELQLSVLSAESLRENCYLGGITLCLKDFDLSRETVKWYKLTTVPYF", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:**... ** .: * *.*.: * ***:**.**: *:::::: * . .:. .. :* . : : **:** * ::**: ***:*:**: ****:****.* :.* * : **.*:. :.*: :*.* ..*:: .. :**: ::* .:*****.* *..* . :*::*: **::* .:* :* *:.:*****:*******:****:: : : * * * :..:. :*.:*:*******.* * ** .. *:******* :*:.. . *.* :. :: : *:**:**** : : . :: .: :* *::.: : * *** *.** *:.***..* **::***: : *****:**** .**: *:* .******:*.. * ********:*.*:::****************:.**:************:*.*****::******::**:**** :*:* ::******** :*:**:*:* :*:* **.:**. : * *:.:* **:*.** ** *::::*:*:::*:::*.*** *** ::*::**:***:*****.::.:. : .. .*:.* ..**: *: ** *:*:* :*: :* : ...:. *** :**:****::*.***.:.***.:*****:*:*:**.::****:*********.*** ******* ***.:* ****::* *:*:*:*.*.:..************ *****:.****:*.*: *:*** ****.:: **: : *:*:*********.*::*. ** : * .*:.*:.: :.:: .: : *::***: *: :**::**** :: .*********.*.* .:.: ::***:**.* *: *****::**** ***.:**:*::: *****:* ***:***:*:* :**.:**:*********::*** *****:**::* *. ***::* .**.: *. ** ** ** :******.:********.*:***** ..:******* :*.**:*:.*********** ****.***:***:::*****:*:**********************:***:***:******:* *:*:***:*:*******:*:*****************************:*:***********:*********:*********************************:************************:** *********.********::********** *******.:****** **************************:*****************************:*:**:::***:*::.***:::*:******* **:******: **.****************:*:* ********.:************:***:*****::.**.:**:**:***: *****: **:*:** ::::.. ..*** *:: * ****:****.************:::**************** **********:******************:***:***************** :***:** ****:**:******:**:..*:", "identical_positions": 1005, "similar_positions": 429, "identity": "58.46%" }, { "cls_id": "homologset.agr.MGI:1203730", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O70173-1", "uniprot_id": "P3C2G_RAT", "id": "O70173-1", "name": "Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma", "aln": "MAYNWQTEPNRAEPQEGGHDHQQCHHADQHLSSRQVRLGFDQLVEELSNKTPLPEDEKE-GTCFVPDTPNLDSKWQSIYGPHPRHFNEFTSQSPHFSQLPFGKASAIGFNPAVLPAHQFIHEGASWRNPTRKYHGGEDPRFSALTPSSTGLDKCHQQGQSGTEHCNYYVEPENNVPHHYSPYSMDSIPDSEEKGSGDADLVEPSLVFSKDSFLPRASENMSVESTEPIGCPLEIVEAPQGSNKSLASFCNNVTKIRGLYHASDTNSNSGKIWAITTAYPSRLFADTQFRVKISTDNSAQLLLLKPPANYLVKDLIAEILLLCANEQLSPKEYLLSICGSEEFLQTDHCLGSHKIFQKSK---SVIQLHLQRSRDTPGKLSRKRDDDRSRVHLNQLLEFTHIWKISRQCLSTVMKSYNLHVEHLLKTQEDVEEKPLSSMFSCGRHPPQPHGNDIIEDVRNICSVLGCIETKQVSDAVKELTLILQRPSQNFHQNSETSKKGFIENVTSELSRSLHQLVDVYCSSFCTDFRPARAPGGVSRDHAGLHSH---LSFTVCSLHNVPETWAHSYKAFSFSCWLTYAGKKLCQVKSCRSLPVTKSFSFSVNWNEIINFPLEIKSLPRESMLVIKLFGIDSATHSANLLAWTCLPLFPKEKSPLGSRLLSMTLQSEPPIEMMAPGVWDGSQPTPLTLQIDFP-AATWEYVKPETEENRTDHQEPPRECLKHIARLSQKQPPLLLSVEKRRYLWFYRFYCNNENSSLPLVLGSAPGWDEGTVSEMHAVLRRWTFSHPLEALGLLTSRFPDQDIREVAVQQLDNFLTDELLDCLPQLVQAVKFEWSLESPLVELLLHRSLQSIRVAHRLFWLLRDAQGEDYFKSWYQELLAALQFCAGEALIEELSKEQKLVKLLGDIGEKVKSAGDAQRKDVLKKEIGSLEEFFKDIKTCHLPLNPALCVKGIDRDACSYFTSNALPLKITFINANPMGKNISVIFKAGDDLRQDMLVLQIIQVMDNVWLQEGLDMQMIIYGCLATGKAQGFIEMVPDAVTLAKIHLHSGLIGPLKENTIKKWFSQHNHLKEDYEKALRNFFYSCAGWCVVTFILGVCDRHNDNIMLTKSGHMFHIDFGKFLGHAQTFGGIKRDRAPFIFTSEMEYFITEGGKNTQHFQDFVELCCRAYNIVRKHSQLLLSLLEMMLHAGLPELRGIEDLKYVHDNLRPQDTDLEATSHFTTKIKQSLECFPVKLNNLIHTLAQMPAFSLARPAPQTPPQECCVLNKTRTIQRVTILGFSKTHSNLYLIEVTRSDNRKNLAKKSFEQFYRLHSQIQKQFPLLTLPEFPHWWHLPFTDSHHERIRDLSHYVEQVLHGSYEVANSDCVLSFFLSEHIQQTLEDSPFVDPGDHSPDKSPQVQLLMTYEDTKLTILVKHLKNIHLPDGSAPSAHVEIYLLPHPSEVRRKKTKCVPKCTDPTYNEIVVYDDVSGLQGHVLMLIVKSKTVFVGAVNIQLCSVPLNEEKWYPLGNSII", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70167-1", "uniprot_id": "P3C2G_MOUSE", "id": "O70167-1", "name": "Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma", "aln": "MAYSWQTEPNRTEPQEDGSDTQQFHHTNQHLSSRQVRLGFDQLVEEINNKTPLSESEKEEDTYFVPDAPNLGSKWPSIYETHPRYFSEFTSQSPDSSQLRFGKLSAIGFNPAVLPTHQLIHEGASWRNPSGKYHGIEYPRFDALPPSSTGQGECNPQGQSGTKHHNYCGEHEGNLPHHHSSYSIDSIPNREKRRSGDVNLVEPSLEFSKDSFLPRTSENVSVESTEPIGCPIEIVEVPQGSNKNLASFCNKVKKIRESYHASDINSNSGKIWAITTAYPSRLFADTKFRVKISIDNSAQLLLLMPHANYLVKDLIAEILLLCANEPLSPKEYLLSVCGSEEFLQMDHSLGSHKIFQKNK---SVIQLHLQKNRDTPGKLSRKSEDDHSPFHLNQLLEFTHIWKISRQCLSTVMKKYNLHVEHLLKPQKDMEEKHLSSMVSGNQHTSQPHVNNVLEEVKNICSVLGCIETKQVSDAVKELNLILQRPSQNFHQNSETSKKGFIERVTAELSRSIYQLIDVYCSSFCTDFQPVHTPGGVSHVHAGLQSH---LSFTVCSLHNVPETWAHSYKAFSFSCWLTYAGKKLCQVKSCRPLPVTKSFSLLVNWNEIINFPLEIKSLPRESMLVIKLFGIDSATHSTNLLAWTCLPLFPRQESVLGSRLFSVTLQSEPPIEMIAPGVWDGSQPSPLTLQIDFP-DAGWEYLKPESEENRTDHEEPPRECLKHIAKLSQKKSPLLLSEEKRRYLWFYRLYCNNENSSLPLVLGSAPGWDEETVSEMHAILRRWTFSHPWEALGLLTSRFPDQDIREVAVQQLDTLLTDELLDCLPQLVQAVKFEWNLESPLVELLPRRPLQSIRVAHCLYWLLRDAQGEAYFKSWYQELLAALQFCAGEALNEELSKEQKLVKLLGDIGEKVKSASDPQRKDVLKKEIGSLEEFFKDIKTCHLPLNPALCIKGIDRDACSYFTSNASPLKITFINANPMGKNISVIFKAGDDLRQDMLALQIIQVMDNAWLQEGLDMQMITYGCLSTGRAQGFIEMVPDAVTLAKIHLHSGLIGPLKENTIKKWFSQHNHLKEDYEKALRNFFYSCAGWCVVTFILGVCDRHNDNIMLTKSGHMFHIDFGKFLGHAQTFGGIKRDRAPFIFTSEMEYFITEGGKNIQHFQDFVELCCRAYNIVRKHSQLILSLLEMMLHAGLPELRGIEDLKYVHNNLRPQDTDLEATSHFTKKIKESLECFPVKLNNLIHTLAQMPALSLAKPAPQTLLQESCILNKTRTIQRVTILGFSKTHSNLYLMEVTCSDNRRSLTKKSFEQFYRLHSQMQKQFSSLALPEFPHWWHLPFTDSDHKRIRDLSHYVEQVLRGSYEVANSDCVLSFFLSEHIQPTLEDSPFVDPGENSLDKSPKVQLLMTYEDSRLTILVKHLKNIHLPDGSVPSAHVEIYLLPHPSEVRRKKTKCVPKCTDPTYNEIVVYDEVLGLQGHVLMLIVKSKTVFVGAVNIQLCSVPLNEEKWYPLGNSII", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75747-1", "uniprot_id": "P3C2G_HUMAN", "id": "O75747-1", "name": "Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma", "aln": "MAYSWQTDPNPNESHEKQYEHQEFLFVNQPHSSSQVSLGFDQIVDEISGKIPHYESEIDENTFFVPTAPKWDSTGHSLNEAHQISLNEFTSKSRELSWHQVSKAPAIGFSPSVLPKPQNTNKECSWGSPIGKHHGADDSRFSILAPSFTSLDKINLEKELENENHNYHIGFESSIPPTNSSFSSDFMPKEENKRSGHVNIVEPSLMLLKGSLQPGMWESTWQKNIESIGCSIQLVEVPQSSNTSLASFCNKVKKIRERYHAADVNFNSGKIWSTTTAFPYQLFSKTKFNIHIFIDNSTQPLHFMPCANYLVKDLIAEILHFCTNDQLLPKDHILSVCGSEEFLQNDHCLGSHKMFQKDK---SVIQLHLQKSREAPGKLSRKHEEDHSQFYLNQLLEFMHIWKVSRQCLLTLIRKYDFHLKYLLKTQENVYN--------------------IIEEVKKICSVLGCVETKQITDAVNELSLILQRKGENFYQSSETSAKGLIEKVTTELSTSIYQLINVYCNSFYADFQPVNVPRCTSYLNPGLPSH---LSFTVYAAHNIPETWVHSYKAFSFTCWLTYAGKKLCQVRNYRNIPDKKLFFFLVNWNETINFPLEIKSLPRESMLTVKLFGIACATNNANLLAWTCLPLFPKEKSILGSMLFSMTLQSEPPVEMITPGVWDVSQPSPVTLQIDFP-ATGWEYMKPDSEENRSNLEEPLKECIKHIARLSQKQTPLLLSEEKKRYLWFYRFYCNNENCSLPLVLGSAPGWDERTVSEMHTILRRWTFSQPLEALGLLTSSFPDQEIRKVAVQQLDNLLNDELLEYLPQLVQAVKFEWNLESPLVQLLLHRSLQSIQVAHRLYWLLKNAENEAYFKSWYQKLLAALQFCAGKALNDEFSKEQKLIKILGDIGERVKSASDHQRQEVLKKEIGRLEEFFQDVNTCHLPLNPALCIKGIDHDACSYFTSNALPLKITFINANPMGKNISIIFKAGDDLRQDMLVLQLIQVMDNIWLQEGLDMQMIIYRCLSTGKDQGLVQMVPDAVTLAKIHRHSGLIGPLKENTIKKWFSQHNHLKADYEKALRNFFYSCAGWCVVTFILGVCDRHNDNIMLTKSGHMFHIDFGKFLGHAQTFGGIKRDRAPFIFTSEMEYFITEGGKNPQHFQDFVELCCRAYNIIRKHSQLLLNLLEMMLYAGLPELSGIQDLKYVYNNLRPQDTDLEATSHFTKKIKESLECFPVKLNNLIHTLAQMSAISPAKSTSQTFPQESCLLSTTRSIERATILGFSKKSSNLYLIQVTHSNNETSLTEKSFEQFSKLHSQLQKQFASLTLPEFPHWWHLPFTNSDHRRFRDLNHYMEQILNVSHEVTNSDCVLSFFLSEAVQQTVEESSPVYLGEKFPDKKPKVQLVISYEDVKLTILVKHMKNIHLPDGSAPSAHVEFYLLPYPSEVRRRKTKSVPKCTDPTYNEIVVYDEVTELQGHVLMLIVKSKTVFVGAINIRLCSVPLDKEKWYPLGNSII", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32T832-1", "uniprot_id": "A0AB32T832_DANRE", "id": "A0AB32T832-1", "name": "", "aln": "------------------------------------------------------------------------------------------------MLKPVAIDIHLFFLGYYCSILQNISFSVRQQKEAPKGLGTAGGEWMVRESCCLEQDRSVRR----PVNAPPMKRTDAALRDRPEDWRLPALEEQEYRELTAAGGAAQSRRTEQDTPLPDTGD-------SSPDWSIRLVDAAQGSNSRTAALCRAAAQL-----LCERVPAAAVLWAPVAPVQESLLGSAELLFRVCVPWLPEPLLYRSQLHWRVQELLEAVLLTLDQSAADAPLYLLKLCSSDQFLRSDEVLGYHECIQAYHRFSADVPVRLVLRDSIRKTLSPDEEDHEQSLHYSQVLQS--ASNHIRWSLQEKLDVYSSAVTRLMRN----------------------------PTGEGVCVLLDSAVGVCAQLCVSTVEMEEAAGRLKSFTKLTLDHSGDLHTAVVALHRSLLKLLQIFFRSFDLDFSVWGTHTHSHTPPSDVQNHRGVLQLSLTSLHTLQPGWRNGYDHLRMSVSVTHSGRNLAEPVQCENISTSLQLHGRIHCNRQLVFPLAVRDLPYESVLCFSLLGCKQG-RCADPLCWAVLPLFSDRTLAHGTLLLSMNTQETNSCPASAALSDTHRQPSGVILQVDFPDSELWRYERVLADTRSVQQWSVCEELESRIRAVCQKHCVSLMSENEKAFLWSKRQSCSSRNALLHLLLGSAPLWAPRDLPELYAVLEHWGPVSHAEALFLISHQFHDQRVRSAAVQCFQQMSDSELEEFLPQLVQALKSEWEIDGPLVKLLLSRSMSSVRIAHQLYWLLLDALQDTLFSSFLSKVVCVLKHCCGRALRLELQQEQRLLDLLTLLAQSVRTADRPKRKELLMRERWKLVSFFADGVSCRLPLDPALLLRGVNTEAFKVFNSNAAPIEVSFITADPLGQNYSIICKTGDNLRQDMLVLQIVRVLDRMWKQEGLDMRMVTYRCISTGPDRGLVEVVGDAVTLAQIHQEWGLSGALREDTLEKWFHMRNKTKEDYEKAVMNFLHSCAGWCVATFVLGICDRHNDNIMLTHSGHMFHIDFGKIMGNAQKFGSIKRDRTPFIFTPEMQRFITGGGENPQRFHRFVELCCDAYNRLRRHTALLLALLQPMLNAGMPEMKDVQDLQYVHNNLRPEDSELEATSYFTRKIKESMESLPVKLNFLIHNMVQLSSKRPEGLSQSQ-------TSSSNNIQQAEIQKYTVKGKDVMYELKVTIEDGFVISQKSFSQLESLHKLLQKHFIESTLPKFPSWFNMSFTP--GRKMTLLNKYLKELFEG--PCRGNEYVCSLFLDGPDADLRSETN--------AQIRPQIQLFLSYKDQKLSVLIKHLKNIRLSNGSCPDAYVVTRLRPDPHEKTKRKTKAVRNNDHPTFNELIEYRNVLKLHGLVLEVTVKSRKAFVAATNVVLGERVLEQEKWFPLGFSEV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. : * . * . * * .: .. .. . : : : . : : . * : .. . * :.: * : .. . .:.:*:..*.**. *::*. . :: .: :. :*: .:. *:..::: .:: .: * . :: *::*: :* :. . ::*.:*.*::**: *. ** *: :* : : : ::* . .** . ::... .: .*:*: : * .* : *. : *:: . :* :*.. .*. : : : . . . .* :. .. * *: :*:::: ** ** . ..: .* *.::: : *.: * :.*. : :: :*::*::*.: . . :. . : :: *. : *** ::.** **:* ..*:* . . :: *.*: ****. . *: *:*:. *. . :. **: : **:*** *.* : :: . : . .* .:* :.**: *:* ::: :** * *...*. * *:***** * :.*::::*.:* *** *:: * ** :*..*** :: : .** : *******:* **.::.***:** *.:.*:::** *:*** :* : *.*: .:::..*:.*.*.** *:.:**:*:.:* :.: *::*. :*:::* :* * .** * :*:***:*** ::*:: :* . *.*** *::::**.*:*:*:* *:* *:**:******.**:::*:*. * ******:*: * *::** :*::::* ******:** . ** *.*:*:*::*** :*: * *****: **::*******.**:**:***********:***********::*:**.**.*****:*****.**: *** **:* *:*: ****** *** :*:*: *:* **: ** **:**: .::**:**::****:*::*****:** ***:*:*.:***** ***.:.*:.: : . ..:..*::. * :: . .:: . :: :::***.*: **. :**:* :**:** *:::.** .:: *.:*:::::. ..: * *:**. .:: : *::**.::*:* :*::*:**:***:*.:** *.*:* * * * * ::***.* : .**:**:: * :* *:* ** : ***:..**.* *: * . *::***:*** * :", "identical_positions": 427, "similar_positions": 463, "identity": "28.22%" }, { "cls_id": "homologset.agr.MGI:1203732", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O70324-1", "uniprot_id": "MOT8_MOUSE", "id": "O70324-1", "name": "Monocarboxylate transporter 8", "aln": "----------------------------------------------------------------------------------------------------------MALPSPASEEAEGPCQEANQEYQEPVCSPVPEPEPEPEPEPEPDPEPVPVPPPEPQPEPEPQPLPDPAPLPELGFEAEPVQEPEPTPTVETRGTARGFQPPEGGFGWIVVFAATWCNGSIFGIHNSVGILYSMLLEE-EKEKNRQVEFQAAWVGALAMGMIFFCSPIVSIFTDRLGCRITATTGAAVAFIGLHTSSFTSSLSLRYFTYGILFGCGCSFAFQPSLVILGHYFQRRLGLANGVVSAGSSIFSMSFPFLIKMLG-------DKIKLAQTFQVLSTFMFVLTLLSLTYRPLLPS---------SQDTPSKRGAHTLRQRFLVQFRKYFNMRVFRQRTYRIWAFGIAAAALGYFVPYVHLMKYVEDKFKEIKETWVLLVCIGATSGLGRLVSGHISDSIPGLKKIYLQVLSFLLLGLMSMMIPLCRDFGGLIVVCLFLGLCDGFFITIMAPIAFELVGPMQASQAIGYLLGMMALPMIAGPPIAGLLR--NCFGD-YHVAFYFAGVPPIIGAVILFFVPLMHQRMFK--KEQRDSSKDKMLSHDPDPNGELLPGSPTPEEPI------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8K1P8-1", "uniprot_id": "MOT8_RAT", "id": "Q8K1P8-1", "name": "Monocarboxylate transporter 8", "aln": "----------------------------------------------------------------------------------------------------------MALPSPASEEAEGPCQEANQEYQEPVCSPVPEPEPEPEPEPEPEPEPVPVPPPEPQPEPEPQPLPDPAPLPVLGFEAEPVQEPEPTPTVETRGTARGFQPPEGGFGWIVVFAATWCNGSIFGIHNSVGILYSMLLEE-EKEKNRQVEFQAAWVGALAMGMIFFCSPIVSIFTDRLGCRITATTGAAVAFIGLHTSSFTSSLSLRYFTYGILFGCGCSFAFQPSLVILGHYFQRRLGLANGVVSAGSSIFSMSFPFLIKMLG-------DRIKLAQTFQVLSTFMFVLTLLSLTYRPLLPS---------SQDTPSKRGAHTLRQRFLVQFRKYFNMRVFRQRTYRIWAFGIAAAALGYFVPYVHLMKYVEDKFKEIKETWVLLVCIGATSGLGRLVSGHISDSIPGLKKIYLQVLSFLLLGLMSMMIPLCRDFGGLIVVCLFLGLCDGFFITIMAPIAFELVGPMQASQAIGYLLGMMALPMIAGPPIAGLLR--NCFGN-YHVAFYFAGVPPIIGAVILFFVPLMHQRMFK--KEQRESSKDKMLSHDPDPNGELLPGSPTPEEPI------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P36021-1", "uniprot_id": "MOT8_HUMAN", "id": "P36021-1", "name": "Monocarboxylate transporter 8", "aln": "----------------------------------------------------------------------------------------------------------MALQSQASEEAKGPWQEADQEQQEPVGS----PEPESEPEPEPEPEPVPVPPPEPQPEP--QPLPDPAPLPELEFESERVHEPEPTPTVETRGTARGFQPPEGGFGWVVVFAATWCNGSIFGIHNSVGILYSMLLEE-EKEKNRQVEFQAAWVGALAMGMIFFCSPIVSIFTDRLGCRITATAGAAVAFIGLHTSSFTSSLSLRYFTYGILFGCGCSFAFQPSLVILGHYFQRRLGLANGVVSAGSSIFSMSFPFLIRMLG-------DKIKLAQTFQVLSTFMFVLMLLSLTYRPLLPS---------SQDTPSKRGVRTLHQRFLAQLRKYFNMRVFRQRTYRIWAFGIAAAALGYFVPYVHLMKYVEEEFSEIKETWVLLVCIGATSGLGRLVSGHISDSIPGLKKIYLQVLSFLLLGLMSMMIPLCRDFGGLIVVCLFLGLCDGFFITIMAPIAFELVGPMQASQAIGYLLGMMALPMIAGPPIAGLLR--NCFGD-YHVAFYFAGVPPIIGAVILFFVPLMHQRMFK--KEQRDSSKDKMLAPDPDPNGELLPGSPNPEEPI------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "G8XYX6-1", "uniprot_id": "MOT8_DANRE", "id": "G8XYX6-1", "name": "Monocarboxylate transporter 8", "aln": "----------------------------------------------------------------------------------------------------------MHSESDDNTAGGTPGSEDPQ------------AEESSSPAEEFEEQERKLAPEDS-----------TVQLIHTGCTD---KRPATPPGAHP---GQGFVPPEGGFGWVVVFAATWCNGSIFGIQNSFGILHMMLVKHHEKQPDQASQFKVAWVGALAMGMIFFCSPVVSMFTDHFGCRKTAVCGAFVAFIGLLTSSFATTLGLWYFTYGILFGCGSSFAFQPSLVILGHYFRQRLGLANGVVTAGSSLFSMGLPVLLKKVV-------EPLGLPRTFQILSIFMLVQALLALAFKPLLPSGMCPMPGMALDGGPSTPESASRWQKGLAKIRRYFNVRVFSILTYRIWAFGVATAVLGYFVPYVHLLNFVKEQFGDTQREWLLLVCIGASSGVGRLLFGKIGDLIPGVKKIYMQVASFILLGVMSMMIPQCAVFEGLVVVFVLMGLCDGCFITIMAPIAFELVGPMQASQAIGYLLGLMAIPMTAGPPIAGLLH--DHFGN-YHVAFYLAGVPPIVGGIVMFFVPLVHQRMQKRRKETDDPSMDKMLKN--CSNGDMLPGYTDMETHI------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q08268-1", "uniprot_id": "MCH4_YEAST", "id": "Q08268-1", "name": "Probable transporter MCH4", "aln": "----------------------------------------------------------------------------------------------------------------MLNIPIIANSKRFLFSKDHEAQSTRDHDVELETRE--GPSSGYNPNFNAADAILKKNSDQ-VDLDVN-KLTNVTSRVLNTPEASLIYDDDREFPDGGLKAWLVVFGAFMGLVPVFGLINSLGAIESYISKH---QLANISSSTISWIFSLYLAISFLSCILSGGYFDRNGSIGLMCTGTVIYAGGLFALANCKSVWQFILAFSVCSGLGTGILMTPLIGTVATWFLKRRGIATSISTMGGSIGGIVFPIMLRKLY-------KEVGFQWAIRILSFICLTCLICASVLARERTK-------PVVQPFKSKAEVAKW------YISSVFNWRYFLEGKFLFVAIGASFAESSLTSCATYLASYSMTRGNTENVAYTMITASNAVGILGRYIPGYFADKFIGRFNVEIITISMAALFNFVMWLPFGGNTKVLWAYVCLWGFSTGSILSLTPVCIGQISKTTDFGKRYATVYLLQALVTIPVLPIGGTLIGKGTVAN-YNHFIIFNSALMAAGAACYIIS-------------RHICVGAKLCKF-------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q08777-1", "uniprot_id": "MCH5_YEAST", "id": "Q08777-1", "name": "Riboflavin transporter MCH5", "aln": "----------------------------------------------------------------------------------------------------------MSSDSLTPKDTIVPEEQTNQLRQPDLDEDSIHYDPEADDLESLETTASYASTSVSAKVYTKKEVNKGTDIESQPHWGENTSSTHDSDKEEDSNEEIESFPEGGFKAWVVTFGCFLGLIACFGLLNSTGVIESHLQDN---QLSSESVSTIGWLFSLFLFVCSASCIISGTYFDRNGFRTIMIVGTVFHVAGLFATANSTKYWHFILSFAIVCGFGNGIVLSPLVSVPAHYFFKRRGTALAMATIGGSVGGVVFPIMLRSFFSMKSDTDPTYGFVWGIRTLGFLDLALLTLSIILVKERLP-------HVIE--NSKDGESRWRYILRVYILQCFDAKAFLDMKYLFCVLGTVFSELSINSALTYYGSYATSHGISANDAYTLIMIINVCGIPGRWVPGYLSDKFG-RFNVAIATLLTLFIVMFVGWLPFGTNLTNMYVISALYGFCSGSVFSLLPVCCGQISKTEEFGKRYSTMYFVVGFGTLVGIPITGAIISIKTTAD-YQHYIIFCGLATFVSAVCYIIS-------------RAYCVGFKWVRF-------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P36032-1", "uniprot_id": "MCH2_YEAST", "id": "P36032-1", "name": "Probable transporter MCH2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSEERHEDHHRDVENKLNLNGKDDINGNTSISIEVPDGGYGWFILLAFILYNFSTWGANSGYAIYLAHYLEN--NTFAGGSKLDYASIGGLAFSCGLFFAPVITWLYHIFSIQFIIGLGILFQGAALLLAAFSVTLWEIYLTQGVLIGFGLAFIFIPSVTLIPLWFRNKRSLASGIGTAGSGLGGIVFNLGMQSILQ-------KRGVKWALIAQCIICTSLSTIALMLTRTTHQG--------------------LRQHKRSYKFELLDYDVLSNFAVWLLFGFVSFAMLGYVVLLYSLSDFTVSLGYTSKQGSYVSCMVSVGSLLGRPIVGHIADKYG-SLTVGMILHLVMAILCWAMWIP-CKNLATAIAFGLLVGSIMGTIWPTIASIVTRIVGLQKLPGTFGSTWIFMAAFALVAPIIGLELRSTDTNGNDYYRTAIFVGFAYFGVSLCQWLLRGFIIARDEIAVREAYSADQNELHLNVKLSHMSKCLFRYKQLPRRV----------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P53918-1", "uniprot_id": "ESBP6_YEAST", "id": "P53918-1", "name": "Uncharacterized transporter ESBP6", "aln": "MSTHSNDYFSASSGMVSETSSEVSSINSSQPVSFSKASIAAPVPCSDLHSTKSNDASRKLSISRTLTNRLNDIKKAVDDDNLQTEENSADVNKILESRFDVADAIRLQHNESVQSKLNIPVTHTTTAGASLSAPSSSAFSASSIQNDTTEHKASMDSKLMRNRLYPASTKHSGKDLEAQGITEFEPDEPTVKKVFTNKSTGQLELPPDGGYGWVVTFCVFLTMFSTWGCNASFGVDLAYYLNH--DTYPGASKYDYALIAGLTVFLGQLLSPLVMALMRIIGLRTTMLFGDAVMLAAYLLASFTTKLWQLYVTQGFMVGCSISLIFVPATTVLPGWFLKKRAVAMGVSLLGTGAGGVVYGLATNKMLS------DFGNTRWCLRIIGISCSISVLVAIALLKERNP--------------TPAIGLKSPRAMFEQLKAMFSLKVITKPFVVLIALWFMFALFAYNMMVFTLSSYAISKGLSSHDASTLTAILNGSQSIGRPLMGLAGDKFG-RANVTIVLTTLLTIYMFAFWIP-AHTFVQLIFFSILVGSCVGVANVMNTVLIADMVKPEEFLPAWAFVNYCGAPFLLVCEVIAQALTVEKDKSNPYLHAQIFCGCCFIAALILISILREYSIRMKLTERQAMTNEKLKEWKASEYDTDSADEDWGKLKERKTKYDLLLGPGIKKYFLRMVYPMKV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .*.: : . :* . . .. . : .* . . : . * . . : . .: .. * . .: : * :* .: . * .: * . .: . . . : : :. : : : . .: : : . ** : * .* .: : : :* : * * . : . . . * : .: * : . : : ", "identical_positions": 19, "similar_positions": 74, "identity": "2.73%" }, { "cls_id": "homologset.agr.MGI:1206039", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35762-1", "uniprot_id": "NKX61_RAT", "id": "O35762-1", "name": "Homeobox protein Nkx-6.1", "aln": "-------------------------------MLAVGAMEGPRQSAFLLSSPP---------------------------------------------------LAALHS-------------------MAEMKTPLYPAAYPPLPTGPPSSSSSSSSSSSPSPPLGAHNPGGLK---------PPAAGGLSSLGSPPQQLSAATPHGINDILSRPSMPVASGAALPSASPSGSS--------------------------------------------------------------------------------------------SSSSSSASATSASAAAAAAAAAAAAAASSPAGLLAGLPRFSSLSPPPPPPGLYFSP--------SAAAVAAVGRYPKP---------LAELPGRTPIFWP---GVMQSPPWRDARLACTP-------HQGSILLDKDGKRKHTRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKKHAAEMATAKKKQDSETERLKGTSENEEDDDDYNKPLDPNSDDEKITQLLKKHKSS---GGSLLLHASEAEGSS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99MA9-1", "uniprot_id": "NKX61_MOUSE", "id": "Q99MA9-1", "name": "Homeobox protein Nkx-6.1", "aln": "-------------------------------MLAVGAMEGPRQSAFLLSSPP---------------------------------------------------LAALHS-------------------MAEMKTPLYPAAYPPLPTGPPSSSSSSSSSSSPSPPLGSHNPGGLK---------PPAAGGLSSLGSPPQQLSAATPHGINDILSRPSMPVASGAALPSASPSGSS--------------------------------------------------------------------------------------------SSSSSSASATSASAAAAAAAAAAAAAASSPAGLLAGLPRFSSLSPPPPPPGLYFSP--------SAAAVAAVGRYPKP---------LAELPGRTPIFWP---GVMQSPPWRDARLACTP-------HQGSILLDKDGKRKHTRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKKHAAEMATAKKKQDSETERLKGTSENEEDDDDYNKPLDPNSDDEKITQLLKKHKSS---GGSLLLHASEAEGSS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P78426-1", "uniprot_id": "NKX61_HUMAN", "id": "P78426-1", "name": "Homeobox protein Nkx-6.1", "aln": "-------------------------------MLAVGAMEGTRQSAFLLSSPP---------------------------------------------------LAALHS-------------------MAEMKTPLYPAAYPPLPAGPPSSSSSSSSSSSPSPPLGTHNPGGLK---------PPATGGLSSLGSPPQQLSAATPHGINDILSRPSMPVASGAALPSASPSGSS--------------------------------------------------------------------------------------------SSSSSSASASSAS-AAAAAAAAAAAAASSPAGLLAGLPRFSSLSPPPPPPGLYFSP--------SAAAVAAVGRYPKP---------LAELPGRTPIFWP---GVMQSPPWRDARLACTP-------HQGSILLDKDGKRKHTRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKKHAAEMATAKKKQDSETERLKGASENEEEDDDYNKPLDPNSDDEKITQLLKKHKSSSGGGGGLLLHASEPESSS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A6J3T5M5-1", "uniprot_id": "A0A6J3T5M5_DROME", "id": "A0A6J3T5M5-1", "name": "", "aln": "MLGSPFLSITPAGGSSNPSPTPPPPDAKVAAKQLAQSFQLSANSAFNLALPPAFYRAPPQQHPECLDYGHEAPEMDLINPYMRHHSFAAAAQGSPPSAAQRHHLAAAMSNGFADVHAHAMAAADYQQQLADYHSAAAAAAVYANNNNNNNNNSSNNNNSSPLMLLKAAHGGGLKDSDSPSTTPPPASSRLHSDSSPSPRYEHNSSPGVDSAKSYALSQRSSGAEDPCQTSESASPPPQGQNDYSPENLSSQRAKFQHHHGVNPLALHNANHAGNPGCHNNNNHMDHKLPLSFLGPPLAALHSMTTEMKGQGVGGSSASANGLSYSHSPNSHLISDRGSGGSSSSSSTTTTNTNSQGAPNPHGIDTILSKPPPVTSAGLSALTGAGIPRFSIAAAAAGMAQYLSQSQGAPLKTHAGHIVDRTHLYWPGLQGLVANPIAWRERLSNTMSANLSQSHQHHPSNDKDGKKKHTRPTFSGQQIFALEKTFEQTKYLAGPERAKLAYALGMSESQVKVWFQNRRTKWRKRHAAEMATAKRKQDD---------MGGDNDGDCSETMDSDNESLDMGESPAQNKRCRSNSSGSSQQQQDNYRH-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . ::: . :*** *: ** *** * :*: ::. .** . . ...**....*** * : : **** ***:. * * .**. : . :. *::. * . :*** *. :...:* *..* * .:. :::::::::: : *. * *: : * .** ...** . ***.*.:.:* . ..: .** ::** *:: .* **: * ** *****:*******************************:***:***:*****************:*********:***. . ::*.* .:.:*.:.:. .: : ::* . ... : .: ", "identical_positions": 139, "similar_positions": 115, "identity": "23.28%" }, { "cls_id": "homologset.agr.MGI:1206040", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9PU42-1", "uniprot_id": "E9PU42_RAT", "id": "E9PU42-1", "name": "Vacuolar protein sorting-associated protein 26C", "aln": "MG-TTLDIKIKRANKVYHAGEMLSGVVVISSKDSVQHQGVSLTMEGTVNLQLSAKSVGVFEAFYNSVKPIQIINSTIDVLKPGKIPSGKTEVPFEFPLLVKGS-KVLYETYHGVFVNIQYTLRCDMRRSLLAKDLTKTCEFIVHSAPQ-KGKLTPSPVDFTITPETLQN---VKERASLPKFLIRGHLNSTNCAITQPLTGELVVEHSDAAIRSIELQLVRVETCGCAEGYARDATEIQNIQIADGDICRNLSVPLYMVFPRLFTCPTLETTNFKVEFEVNVVVLLHADHLITENFPLKLCRT-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35075-1", "uniprot_id": "VP26C_MOUSE", "id": "O35075-1", "name": "Vacuolar protein sorting-associated protein 26C", "aln": "MG-TTLDIKIKRANKVYHAGEMLSGVVVISSKDSVQHQGVSLTMEGTVNLQLSAKSVGVFEAFYNSVKPIQIINSTIDVLKPGKIPSGKTEVPFEFPLLVKGS-KVLYETYHGVFVNIQYTLRCDMRRSLLAKDLTKTCEFIVHSAPQ-KGKLTPSPVDFTITPETLQN---VKERASLPKFFIRGHLNSTNCAITQPLTGELVVEHSDAAIRSIELQLVRVETCGCAEGYARDATEIQNIQIADGDICRNLSVPLYMVFPRLFTCPTLETTNFKVEFEVNVVVLLHADHLITENFPLKLCRT-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14972-1", "uniprot_id": "VP26C_HUMAN", "id": "O14972-1", "name": "Vacuolar protein sorting-associated protein 26C", "aln": "MG-TALDIKIKRANKVYHAGEVLSGVVVISSKDSVQHQGVSLTMEGTVNLQLSAKSVGVFEAFYNSVKPIQIINSTIEMVKPGKFPSGKTEIPFEFPLHLKGN-KVLYETYHGVFVNIQYTLRCDMKRSLLAKDLTKTCEFIVHSAPQ-KGKFTPSPVDFTITPETLQN---VKERALLPKFLLRGHLNSTNCVITQPLTGELVVESSEAAIRSVELQLVRVETCGCAEGYARDATEIQNIQIADGDVCRGLSVPIYMVFPRLFTCPTLETTNFKVEFEVNIVVLLHPDHLITENFPLKLCRI-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VPC3-1", "uniprot_id": "Q9VPC3_DROME", "id": "Q9VPC3-1", "name": "Vacuolar protein sorting-associated protein 26C", "aln": "MSSLLFDIKLKRENKVYHENDMLLGCVQFQCAQETKHEGIILYLEGIVNLQLSAKTVGLFDAFYNSVKPINLLQNSLELSAPGKLSAGRSEFHFELPLVCKKEPRILYETYHGVFINVNYQLTCTVKRNFLGKATTKIQQFCVQYKPVPLSEDSKKVVPFSLSPDSLQKNASAKERLSMPRFLITGRLDRSEFCVTTPITGSITVQHTEAAIKSIEMQLVRVETCGCDEGYSKDATEIQTIQIADGNVLPKLELPIHMVLPRLFTCPTLLTKNFKIEFELNLIVVFKEDYTVSENFKIVLKRSTGPLPSKVTTAGR", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. :***:** ***** .::* * * :.. :..:*:*: * :** ********:**:*:*********::::.:::: ***:.:*::*. **:** * . ::*********:*::* * * ::*.:*.* ** :* *: * .: : . * *:::*::**: .*** :*:*:: *:*: :: :* *:**.:.*: ::***:*:*:********** ***::******.******:: *.:*::**:********* *.***:***:*::*::: *: ::*** : * * ", "identical_positions": 145, "similar_positions": 100, "identity": "45.89%" }, { "cls_id": "homologset.agr.MGI:1206571", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O54831-1", "uniprot_id": "PR7A2_MOUSE", "id": "O54831-1", "name": "Prolactin-7A2", "aln": "MSFSFSQPCPSGALLLVVVSSLLLWENVASVPLSSNETDGYPLSINGLFHNAMRLTWNIKNLNMELRKTYTVNQVSEKLYENYMLDFIEDMEYLVKALTCCHNYSIKTPENLDEAQQIPFNEFPKLILSRMWAWNETSKVLLTTLRSIPGMHDDVISLAKNIETKLAELFEYTQSILNSIYGTTTTGNVEYTVFSGLEDLKSSDEEFSLFDLCKFSYCLRVDIHMVELYLKLLECVVYVSSDVCLSKNIRDAS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9R006-1", "uniprot_id": "PR7A2_RAT", "id": "Q9R006-1", "name": "Prolactin-7A2", "aln": "MQLSFSRPRP-WTLLLMVVSNLLLWENVSSGNLNSNETDGDLLLHRGLFDTATRLSQDIRDLDIEFLRMYAVNEVSEKLYNKHMLEFIEDMDFVVKALTCCHNYSIKTPENLDEAQQIPFNDFPWLILSRMWGWNETSKNLLTILRSIPGMHDDVISLAQAIERKLAELFEYTQSILTLIFG--PTENVDRSIFSGLEDLKASDEELRFFALCKFSYCLRVDLQTIELYFKLLQCAVNVNSNVCLSINSEDSS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9PST6-1", "uniprot_id": "E9PST6_RAT", "id": "E9PST6-1", "name": "", "aln": "MPLSFPQPRL-WALPLMVVSNLLLWDNVASGTLTSHETDGDPVSIKGLLNNATRVSQNIRNLNIVLRRKYTVNEISPLLFGSNIHDFHEHMEFVVKTLTSCHNYSIKTPENLDKARQIPFKDFPKLILSRVWAWNETSKNLLNILRSNPETHDDVISLAKDIETKLAELSEYIQSILSSIYG--PTEDVDYTIFSGLEDLRSSHDEFRIFALCKFSYCLRDDIRMIELYLELLECVKNVNVDMCLSNYSRDAS", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :**.:* :* *:***.****:**:* *.*:**** : .**:..* *:: :*::*:: : : *:**::* *: . : :* *.*:::**:**.*************:*:****::** *****:*.****** **. *** * ********: ** ***** ** ****. *:* .* :*: ::*******::*.:*: :* ********* *:: :***::**:*. *. ::*** .*:*", "identical_positions": 135, "similar_positions": 70, "identity": "53.36%" }, { "cls_id": "homologset.agr.MGI:1206572", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AW68-1", "uniprot_id": "A0A8I6AW68_RAT", "id": "A0A8I6AW68-1", "name": "", "aln": "MYHTY-----SGALLLLVVSSLLLWENVASVPLRSSETDDDTLSIKELFDHAMILSKNISDLNMELHRIFTISKISAKLFDKFVSTLFTS-----IFFPFNGQ------NLTYYHKYSIKTPEDIDEAQKVISLKDFPYVILIRMQAWNETFRNIINLLEDMPVMGDHILPIFKNIKTKNGELLEDTKSIFSHFYGTTENVDDCTLWSGLEDFQSSDEESQFLSLCKLSYCLHVDIHTADLYLQLLKCMVFVNSGICLPPKLKMIHDAVLFLNSLIFIHCKDNHE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O54830-1", "uniprot_id": "PR7A1_MOUSE", "id": "O54830-1", "name": "Prolactin-7A1", "aln": "MPLSFTQPCSSGALLLLVVSNLLLWENVACLPLSSNDTDDDPLSIKGLLDHAMILSKNITDLNMELRRIFTISEMSAKLIDKFLSSSSSSDSYDQFMLEFLGQQELLTKNLTYCHKYSIKVPEDIEEAQNVISLEDFPILILSRMQAWNETLKNRINLSEGTPGIDDDILPIYKNIETKIAELLEDSKSILSQAYGATENVADYTLWSGLEDLQSSDEETRFLALCKLSYCLHVDIHTANFYLQFLRCVALVNSDSCLSS--KTGNDS-----------------", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :: **********.********.:** *.:****.**** *:**********:******:******::****:***:*: :* ::: * ** **** ******.****:***:****:*** :** ********::* *** *. * :.*.****:***:** .*****:***:*: **:**** * ********:******::**:***************::***:*:*:.:***. **.. * :*: ", "identical_positions": 174, "similar_positions": 54, "identity": "61.05%" }, { "cls_id": "homologset.agr.MGI:1206579", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35257-1", "uniprot_id": "PR6A1_MOUSE", "id": "O35257-1", "name": "Prolactin-6A1", "aln": "----MLSLSQPCFSGTLLMLLASNFLLWKNVAPVPMYASLDEYGEMSIYDLLDHVTILSHNVSELTAEMHRIFMEDVRYKPGRWFSDRYLTACHTSTLTISVSKEGARQMPGVFLVKEMISMLTAWRYPLYHIITELSYMEQAPDEIISRARNIEEKIIVLIEALRGILSKIQPGPPENERYPVWNELASLQSPDEDLRHLTLFNLFQCLVKDSRKIDSSIRLLKCKLLYNRDC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P24800-1", "uniprot_id": "PR6A1_RAT", "id": "P24800-1", "name": "Prolactin-6A1", "aln": "MVKSWLRMSKKMEAGTLLMLLMSNILLWENVASVPRHASGAGRGEMSLHGLLDHAIILAHNVTELIAEMNSVFLEDVLYKPGRWFPERDLTACHRSPFTIAVSKEGTQQRLGVFLVKEMIGMLETWTFSLYHIANEMSHMEEPPDEIISRAKNIEEKIKELMDVLKGILNKIQPGSPQNERFPMWNELAYLRSPDEERRHFAFTNLFQCLLQDSRKFDSKVRLLKCRLIYNRDC", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :*: :******* **:***:***.** :** ****::.****. **:***:** ***: :*:*** *******.:* ***** *.:**:*****::* *********.** :* :.**** .*:*:**:.********:****** *::.*:***.*****.*:***:*:***** *:****: **::: ******::****:**.:*****:*:*****", "identical_positions": 149, "similar_positions": 54, "identity": "63.68%" }, { "cls_id": "homologset.agr.MGI:1206581", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K344-1", "uniprot_id": "PK3CA_RAT", "id": "A0A0G2K344-1", "name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "aln": "MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLVTIKHELFKEARKYPLHQLLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFVIGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKHIYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLKLCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPIDSFTMPSYSRRISTATPYMNGETATKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGIYHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHCPLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWFSSVVKFPDMSVIEEHANWSVSREAGFSYSHTGLSNRLARDNELRENDKEQLRALCTRDPLSEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAMELLDCNYPDPMVRSFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRQPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKG-AQEYTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALEYFTKQMNDAHHGGWTTKMDWIFHTIKQHALN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P42337-1", "uniprot_id": "PK3CA_MOUSE", "id": "P42337-1", "name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "aln": "MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLVTIKHELFREARKYPLHQLLQDETSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFVIGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKHIYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLKLCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPIDSFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGIYHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHCPLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWFSSVVKFPDMSVIEEHANWSVSREAGFSYSHTGLSNRLARDNELRENDKEQLRALCTRDPLSEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAMELLDCNYPDPMVRSFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRQPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKG-AQEYTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALEYFTKQMNDAHHGGWTTKMDWIFHTIKQHALN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P42336-1", "uniprot_id": "PK3CA_HUMAN", "id": "P42336-1", "name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "aln": "MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQLLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFAIGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKHIYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLKLCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMDCFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGIYHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHCPLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWFSSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLKAISTRDPLSEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAMELLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKG-AQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QAD7-1", "uniprot_id": "F1QAD7_DANRE", "id": "F1QAD7-1", "name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "aln": "MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHHLLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFAIGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDASGAHSRALYVYPPNVESSPELPKHIYGKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSAEQLKMCVQEYQGKYILKVCGCDEYLLEKYPISQYKYVRSCIMLGRLPNLMLMSKDSLYSQLPMDNFTMPSYSRRISTATPYMNGEASTKSLWTINSTLRIRVLCATYVNVNIRDIDKIYVRTGIYHGGEQLCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHCPLAWGNVNLFDYTHTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDYFSSPVKFPDMATIEDHANWIISREMGYNYCQSGQSSRVARDHAMTEADIEQLRQLGNRDPLSEITEQEKDFLWRHRQYCVNIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAMELLDCNYPDPMIRDFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRRPDYMDALQNFTSPLNPAHQLGNLRLEDCRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSTTLHQWLKDKNKGEMYDMAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRHHAQN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**********************:********:**********:*******:********:***:*:****************:************************************.*********:******************::*:*** ...****:******************.****************************************************:****:** ****************:*****:*****:********:******:*:*******:* ********************::*****.***:***::*************************** *********************.**:****:******************************:******.********************************************:*** ******:.**:**** :*** *:.*.::* *.*:***: : * * ***: : .**************** **:***.*******:**:***************:****.******************:*.********************************** ******************************************************.*************************************:**:*****.* ***************:************************************************************************************.********************* *************:** *************************************************************************** :** *****************************************************************:** **********************::** *", "identical_positions": 972, "similar_positions": 74, "identity": "90.93%" }, { "cls_id": "homologset.agr.MGI:1206582", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97707-1", "uniprot_id": "CCG1_RAT", "id": "P97707-1", "name": "Voltage-dependent calcium channel gamma-1 subunit", "aln": "MSQTKTAKVRVTLFFILAGGVLAMVAVVTDHWAVLSPHLEHHNETCVAAHFGLWRICTTWVAMHNQ---DKNCDGTIPAGEKNCSYFRHFNPGESSEIFEFTTQKEYSISAAAIAIFSLGFIIIGSICAFLSFGNKRDYLLRPASMFYAFAGLCLIVSVEVMRQSVKRMIDSEDTVWIEYYYSWSFACACAGFTLLFLGGLFLLLFSLPRMPQNPWESCMDTESEH--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70578-1", "uniprot_id": "CCG1_MOUSE", "id": "O70578-1", "name": "Voltage-dependent calcium channel gamma-1 subunit", "aln": "MSQTKTAKVRVTLFFILVGGVLAMVAVVTDHWAVLSPHLEHHNETCEAAHFGLWRICTARVAVHNK---DKSCEHVTPSGEKNCSYFRHFNPGESSEIFEFTTQKEYSISAAAIAIFSLGFIIVGSICAFLSFGNKRDYLLRPASMFYAFAGLCLIVSVEVMRQSVKRMIDSEDTVWIEHYYSWSFACACAAFILLFLGGLFLLLFSLPRMPQNPWESCMDAEPEH--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q06432-1", "uniprot_id": "CCG1_HUMAN", "id": "Q06432-1", "name": "Voltage-dependent calcium channel gamma-1 subunit", "aln": "MSQTKMLKVRVTLFCILAGIVLAMTAVVTDHWAVLSPHMEHHNTTCEAAHFGLWRICTKRIPMDD----SKTCGPITLPGEKNCSYFRHFNPGESSEIFEFTTQKEYSISAAAIAIFSLGFIILGSLCVLLSLGKKRDYLLRPASMFYAFAGLCILVSVEVMRQSVKRMIDSEDTVWIEYYYSWSFACACAAFILLFLGGLALLLFSLPRMPRNPWESCMDAEPEH--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QF71-1", "uniprot_id": "A0A8M9QF71_DANRE", "id": "A0A8M9QF71-1", "name": "Voltage-dependent calcium channel gamma-1 subunit", "aln": "--MRKETKTKVLFFVILVGSVCMFTAVVTDHWAVLSPRVNNINTTCEAVHFGLWKLCKKHIYIEDKEYVGKGCGPISLPGEMNCSYFRHFTPGKDSDIFEVKTQREYNISGAAIALFSLAFVILGTLCVLCSLKKGKDYMYKPAGMFFTFAGLCAFISVEVMRQSVLRMIDSKHTIWIEYYYSWSFACAYTGFVLLLLSGIGLVLVSMPQMPRNPWESCMDAEPEQM-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E7F1R5-1", "uniprot_id": "E7F1R5_DANRE", "id": "E7F1R5-1", "name": "Voltage-dependent calcium channel gamma-1 subunit", "aln": "MLEDKKTKVKITFLVILVGISSMLAAVVTDHWAVLSPRVERLNTTCEAAHFGLWRLCKKSIFIVEEDPQGKGCGPISLPGVKNCSYFKHFTSGEEAEVFEVKTQKEYNISAAAIAIFSLAFMTLGSLCLLGAFGKGRDYLLRPAGMFFAFAGLCIVISVEVMRQSVKRMIDSDETIWIEYYYSWSFACACAAFTLLFLSGITLLIISMPHMPRNPWETCMDAEPEPID", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * *.:: :: **.* :.************:::. * ** *.*****::*. : : : .* * .* *****:**..*:.:::**..**:**.**.****:***.*: :*::* : :: : :**: :**.**::***** .:********* *****..*:***:********* :.* **:*.*: *::.*:*:**:****:***:*.* ", "identical_positions": 113, "similar_positions": 70, "identity": "49.56%" }, { "cls_id": "homologset.agr.MGI:1206586", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZHS6-1", "uniprot_id": "BAP1_RAT", "id": "D3ZHS6-1", "name": "Ubiquitin carboxyl-terminal hydrolase BAP1", "aln": "-----------------------------------------MNKGWLELESDPGLFTLLVEDFGVKGVQVEEIYDLQSKCQGPVYGFIFLFKWIEERRSRRKVSTLVDDTSVIDDDIVNSMFFAHQLIPNSCATHALLSVLLNCS--NVDLGPTLSRMKDFTKGFSPESKGYAIGNAPELAKAHNSHARPEPRHLPEKQ-NGLSAVR-TMEAFHFVSYVPITGRLFELDGLKVYPIDHGPWGEDEEWTDKARRVIMERIGLATAGEPYHDIRFNLMAVVPDRRVKYEARLHVLKGNRQTVLEALQQL-----IRVTQPELIQTHKSQESQLPEESKPASSKSPFGLEAGRTPAASECTHTDGAEEVAGSCPQTTTHSPPSKSKLVVKPSGSSLNGVPPTPTP--IVQRLPAFLDNHNYAKSPMQEEEDLAAGVGRSRVPVR-PQQYSDDEEDYEDEEED-VQNTSSAIRYKRKGTGKPGSLSNSSDGQLSVLQPN-TINVLTEKLQESQK-------DLSIPLSIKTSSGAGSPAVAVPTHSQPSPTPSNESTDTASEIGSAFNSPLRSPIRSANPTRPSSPVTSHISKVLFGEDDSLLRVDCIRYNRAVRDLGPVISTGLLHLAEDGVLSPLALTEGGKGSSPS-------TRSSQGSQGSSSLEE-----------KEVVEVTDSRD---KSGLNRSSEPLSGEKYSPKELLALLKCVEAEIANYEACLKEEVEKRKKFKIDDQRRTHNYDEFICTFISMLAQEGMLANLVEQNISVRRRQGVSIGRLHKQRKPDRRKRSRPYKAKRQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99PU7-1", "uniprot_id": "BAP1_MOUSE", "id": "Q99PU7-1", "name": "Ubiquitin carboxyl-terminal hydrolase BAP1", "aln": "-----------------------------------------MNKGWLELESDPGLFTLLVEDFGVKGVQVEEIYDLQSKCQGPVYGFIFLFKWIEERRSRRKVSTLVDDTSVIDDDIVNNMFFAHQLIPNSCATHALLSVLLNCS--NVDLGPTLSRMKDFTKGFSPESKGYAIGNAPELAKAHNSHARPEPRHLPEKQ-NGLSAVR-TMEAFHFVSYVPITGRLFELDGLKVYPIDHGPWGEDEEWTDKARRVIMERIGLATAGEPYHDIRFNLMAVVPDRRIKYETRLHVLKVNRQTVLEALQQL-----IRVTQPELIQTHKSQESQLPEESKPASSKSPLGLEAGRTPVASECTQTDGAEEVAGSCPQTTTHSPPSKCKLVVKPPGSSLNGVPPNPAP--IVQRLPAFLDNHNYAKSPMQEEEDLAAGVGRSRVPVRAPQQYSEDEDDYEDEDED-VQNTNPAIRYKRKGTGKPGSLSNSSDGQLSVLQPN-TINVLTEKLQESQK-------DLSVPLSIKTSSGAGSPAVAVPTHSQPSPTPSNESTDTASEIGSAFNSPLRSPIRSANPTRPSSPVTSHISKVLFGEDDSLLRVDCIRYNRAVRDLGPVISTGLLHLAEDGVLSPLALTEGGKGSSPS-------TRSSQGSQGSSGLEE-----------KEVVEVTESRD---KPGLNRSSEPLSGEKYSPKELLALLKCVEAEIANYEACLKEEVEKRKKFKIDDQRRTHNYDEFICTFISMLAQEGMLANLVEQNISVRRRQGVSIGRLHKQRKPDRRKRSRPYKAKRQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92560-1", "uniprot_id": "BAP1_HUMAN", "id": "Q92560-1", "name": "Ubiquitin carboxyl-terminal hydrolase BAP1", "aln": "-----------------------------------------MNKGWLELESDPGLFTLLVEDFGVKGVQVEEIYDLQSKCQGPVYGFIFLFKWIEERRSRRKVSTLVDDTSVIDDDIVNNMFFAHQLIPNSCATHALLSVLLNCS--SVDLGPTLSRMKDFTKGFSPESKGYAIGNAPELAKAHNSHARPEPRHLPEKQ-NGLSAVR-TMEAFHFVSYVPITGRLFELDGLKVYPIDHGPWGEDEEWTDKARRVIMERIGLATAGEPYHDIRFNLMAVVPDRRIKYEARLHVLKVNRQTVLEALQQL-----IRVTQPELIQTHKSQESQLPEESKSASNKSPLVLEANRAPAASEGNHTDGAEEAAGSCAQAPSHSPPNKPKLVVKPPGSSLNGVHPNPTP--IVQRLPAFLDNHNYAKSPMQEEEDLAAGVGRSRVPVRPPQQYSDDEDDYEDDEEDDVQNTNSALRYKGKGTGKPGALSGSADGQLSVLQPN-TINVLAEKLKESQK-------DLSIPLSIKTSSGAGSPAVAVPTHSQPSPTPSNESTDTASEIGSAFNSPLRSPIRSANPTRPSSPVTSHISKVLFGEDDSLLRVDCIRYNRAVRDLGPVISTGLLHLAEDGVLSPLALTEGGKGSSPS-------IRPIQGSQGSSSPVE-----------KEVVEATDSRE---KTGMVRPGEPLSGEKYSPKELLALLKCVEAEIANYEACLKEEVEKRKKFKIDDQRRTHNYDEFICTFISMLAQEGMLANLVEQNISVRRRQGVSIGRLHKQRKPDRRKRSRPYKAKRQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1L2G3-1", "uniprot_id": "BAP1_DANRE", "id": "A1L2G3-1", "name": "Ubiquitin carboxyl-terminal hydrolase BAP1", "aln": "-----------------------------------------MNKGWLELESDPGLFTLLVEDFGVKGVQVEEIYDLQSKCQSPVYGFIFLFKWIEERRSRRKVSTLVDETSVIDDDIVNDMFFAHQLIPNSCATHALLSVLLNCS--GVELGMTLSRMKAFTKGFNPESKGYAIGNAPELAKAHNSHARPEPRHLPEKQ-NGISAVR-TMEAFHFVSYVPIKDRLFELDGLKAYPIDHGPWGEDEEWTDKARRVIMERIGLATAGEPYHDIRFNLMAVVPDRRIKYESKLDILKRNRQIILEGLQQIREKKVIRMTQQESGQDRKQQDSSSSEDTPPVVKKE--EVQETPIPSGAEQATPTEAQEGAASLPSPAGKVR-SMAKPALPAGGAPPPAPLPAPSTNTIVQRLPAFLDNHNYAKSPMQEEEDLAAGVGRSRPPQP---PYSDDEDDYDDEEEECSTAGVTNSRVRRKLGLRTRTMSRTAVGGVAAMEGQLALSVLAEKLKKEVQRKDALATTGSTPLNVRTEGRTG--GISITSACQPSPTPSNESTDTASEIGSAFNSPLRSPARSQATTRPSSPVASHVGRVLFGEEEGLPRLD-ARHNRAVRDLGVLVSSTQLQLQEDGVIFALPPTEALEGLKKVGGVDKKKKEEASGPGGEEEVKEGPSVEMKAEDVKESVDVKPEKENLPTTDVENSTKPP-GEKYTPKELLALLKYVEADIANYEVYLKEEVEKRKKYKIDDQRRTHNYDEFICTFISMLAQEGMLASLVEQNISVRRRQGVSIGRLHKQRKPDRRKRSRPYKAKRQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7K5N4-1", "uniprot_id": "CALYP_DROME", "id": "Q7K5N4-1", "name": "Ubiquitin carboxyl-terminal hydrolase calypso", "aln": "MNAAGGGSGAQAAAVAAGNNSLSHNALLSTASGATTMPMAQLADGWLELESDPGLFTLLLKDFGCHDVQVEEVYDLQKPIESP-YGFIFLFRWIEERRARRKIVETTAEIFVKDEEAISSIFFAQQVVPNSCATHALLSVLLNCNENNLQLGDTLSRLKTHTKGMSPENKGLAIGNTPELACAHNSHAMPQARRRLERTGAGVSSCRFTGEAFHFVSFVPINGQLFELDGLKPYPMNHGGWEDSEDWTDKFRRVMAERLGIATGEQ---DIRFNLMAVVPDRRIAITHKLKMLRTNQAIVSGTLQKL-------------------------------------------------------------------------------------------------------------------LKADEQGESGNGDSQRPDT-------------------------------------------------------------------------------------------------------PTTLLEPSAFTARDLQSLLKN---------------LDTEIAINEQHLADENDRRHMFKVDASRRTHNYDKFICTFLSMLAHQGVLGELVSQHLLPSKKVS----------GQGAANRISKQS--------------------------TTASAGGSTAAGTASTPK-------------------------------------------------------------TQQQQAAAAKNGKSP-----SKTPGRRRKGRNKCRKRK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .***************::*** :.*****:****. :.* *******:******:***: . : * *:: :..:***:*::****************. .::** ****:* .***:.**.** ****:**** ****** *:.*: *: *:*: * * *******:***..:******** **::** * :.*:**** ***: **:*:**. : **************: :*.:*: *: : **:: :: :*: :* * *: * ..* : *: ** :: * ::. . :.. :.:::. :: .* .:: . .:.: * .:**: * . . . .*. . . . .. * :** .:*: :. ::* * .:.*.**::.* **:", "identical_positions": 184, "similar_positions": 128, "identity": "22.72%" }, { "cls_id": "homologset.agr.MGI:1206587", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35256-1", "uniprot_id": "PR4A1_MOUSE", "id": "O35256-1", "name": "Prolactin-4A1", "aln": "MHLSLTPQWSSWTVLLLLVSNLLLWENTASAMRAKRLNVHDYTTFGNTWNQAIQLSQSMNHRISELSTHFKVFYAQGRGFEKRTTRCHTSSLSSPENKEQAQKIQLEVLLGLAHSLLQAWVNPLYHLWAEMCERLGSTPPILSKALEVKTLNRNLLETIEKIAFKGNFEINENGNYTAWSELELLQSPNRDTRYFAFHNLFHCLKKDSSHVEMYLKLLKCRLIQSNC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P09320-1", "uniprot_id": "PR4A1_RAT", "id": "P09320-1", "name": "Prolactin-4A1", "aln": "MHLSLSHQWSSWTVLLLLVSNLLLWENTASAMRAKLLNVHNYTSYGDTWNQAIKISQDMNQYISDLSTHVKIFYAQGRGFERRTTRCHTSSLSSPENKEQAQQFQLEVLLGLSHSLLQAWLNPLHHLWAEMCDRLGSTPPTLYKALMLKESNIKLLDAIKNIAKKGNFEINEKANYTAWSELGFLQSPNRDTRYFAFYNLFHCLKKDSNNVEMYLKLLKCRLIRSKC", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*****: **************************** ****:**::*:******::**.**: **:****.*:*********:********************::********:*******:***:*******:******* * *** :* * :**::*::** ********:.******** :*************:**********.:*************:*:*", "identical_positions": 183, "similar_positions": 33, "identity": "80.62%" }, { "cls_id": "homologset.agr.MGI:1206591", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O70337-1", "uniprot_id": "BIK_MOUSE", "id": "O70337-1", "name": "Bcl-2-interacting killer", "aln": "MSEARLMARDV-IKTVPHDQVPQPP---VASETPSMK--EPVRDVDLMECVEGRNQVALRLACIGDEMDLCLRSPRLVQLPGIAIHRL--AVTYSRTG-VRGIFRSLIRSLTNLRENIWS-WRVLTPGAWVSPDQDPGQLFPMVLLVFLLLGGAWYLQLQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13323-1", "uniprot_id": "BIK_HUMAN", "id": "Q13323-1", "name": "Bcl-2-interacting killer", "aln": "MSEVRPLSRDILMETLLYEQLLEPPTMEVLGMTDSEEDLDPMEDFDSLECMEGSDALALRLACIGDEMDVSLRAPRLAQLSEVAMHSLGLAFIYDQTEDIRDVLRSFMDGFTTLKENIMRFWRSPNPGSWVSCEQVLLALLLLLALLLPLLSGGLHLLLK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***.* ::**: ::*: ::*: :** * . * * : :*:.*.* :**:** : :************:.**:***.**. :*:* * *. *.:* :*.::**:: .:*.*:*** ** .**:*** :* *: :: *:: **.*. :* *:", "identical_positions": 68, "similar_positions": 53, "identity": "42.5%" }, { "cls_id": "homologset.agr.MGI:1261415", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CHN6-1", "uniprot_id": "SGPL1_RAT", "id": "Q8CHN6-1", "name": "Sphingosine-1-phosphate lyase 1", "aln": "-------------MPSTDLLKLKDFEPYLEILEAYSTKAKNYVNGYCTKYEPWQ------LIAGSVLCTLLVVWVYELIFQPESLWSR----FKNKLFRLIRKMPFIGRKIQQQLTKAKKDLVKNMPFLKLDKDYVKTLPAQGLSTAEVLERLKEY-SSMDVF-WQEGKASGAVYSGEPKLTELLVQAYGEFTWSNPLHPDIFPGLRKLEAEIVRMTCSLFNGGPDS-CGCVTSGGTESILMACKAYRDLALE-KGIKTPEIVAPESAHAAFDKAAHYFGMKIVRVAQK-KNMEVDVRAMKRAISRNTAMLVCSAPQFPHGVIDPIPEVAKLAVKYKIPFHVDACLGGFLIVFMEKAGYPLEKPFDFRVKGVTSISADTHKYGYAPKGSSVVMYSNEKYRKYQFFVDADWQGGIYASPSIAGSRPGGIIAACWAALMHFGENGYVEATKQIIKTAR-FLKSELENIKNIFILGDPQLSVIALGSNDFDIYRLSNMMSAKGWNFNYLQFPRSIHFCITLVHTRKRVAIQFLKDIRESVTQIMK--NPKAKTTGMGAIYGMAQATIDRKMVAEISSVFLDSLYSTDPVTQGNQMNGSPKPR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R0X7-1", "uniprot_id": "SGPL1_MOUSE", "id": "Q8R0X7-1", "name": "Sphingosine-1-phosphate lyase 1", "aln": "-------------MPGTDLLKLKDFEPYLEILESYSTKAKNYVNGYCTKYEPWQ------LIAWSVLCTLLIVWVYELIFQPESLWSR----FKKKLFKLIRKMPFIGRKIEQQVSKAKKDLVKNMPFLKVDKDYVKTLPAQGMGTAEVLERLKEY-SSMDGS-WQEGKASGAVYNGEPKLTELLVQAYGEFTWSNPLHPDIFPGLRKLEAEIVRMTCSLFNGGPDS-CGCVTSGGTESILMACKAYRDLALE-KGIKTPEIVAPESAHAAFDKAAHYFGMKIVRVALK-KNMEVDVQAMKRAISRNTAMLVCSTPQFPHGVMDPVPEVAKLAVRYKIPLHVDACLGGFLIVFMEKAGYPLEKPFDFRVKGVTSISADTHKYGYAPKGSSVVMYSNEKYRTYQFFVGADWQGGVYASPSIAGSRPGGIIAACWAALMHFGENGYVEATKQIIKTAR-FLKSELENIKNIFIFGDPQLSVIALGSNDFDIYRLSNMMSAKGWNFNYLQFPRSIHFCITLVHTRKRVAIQFLKDIRESVTQIMK--NPKAKTTGMGAIYGMAQATIDRKLVAEISSVFLDCLYTTDPVTQGNQMNGSPKPR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95470-1", "uniprot_id": "SGPL1_HUMAN", "id": "O95470-1", "name": "Sphingosine-1-phosphate lyase 1", "aln": "-------------MPSTDLLMLKAFEPYLEILEVYSTKAKNYVNGHCTKYEPWQ------LIAWSVVWTLLIVWGYEFVFQPESLWSR----FKKKCFKLTRKMPIIGRKIQDKLNKTKDDISKNMSFLKVDKEYVKALPSQGLSSSAVLEKLKEY-SSMDAF-WQEGRASGTVYSGEEKLTELLVKAYGDFAWSNPLHPDIFPGLRKIEAEIVRIACSLFNGGPDS-CGCVTSGGTESILMACKAYRDLAFE-KGIKTPEIVAPQSAHAAFNKAASYFGMKIVRVPLT-KMMEVDVRAMRRAISRNTAMLVCSTPQFPHGVIDPVPEVAKLAVKYKIPLHVDACLGGFLIVFMEKAGYPLEHPFDFRVKGVTSISADTHKYGYAPKGSSLVLYSDKKYRNYQFFVDTDWQGGIYASPTIAGSRPGGISAACWAALMHFGENGYVEATKQIIKTAR-FLKSELENIKGIFVFGNPQLSVIALGSRDFDIYRLSNLMTAKGWNLNQLQFPPSIHFCITLLHARKRVAIQFLKDIRESVTQIMK--NPKAKTTGMGAIYGMAQTTVDRNMVAELSSVFLDSLYSTDTVTQGSQMNGSPKPH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V7Y2-1", "uniprot_id": "SGPL_DROME", "id": "Q9V7Y2-1", "name": "Sphingosine-1-phosphate lyase", "aln": "---------------------MRPFS-----GSDCLKPVTEGINRAFGAKEPWQ------VATITATTVLGGVWLWTVICQDENLYIR----GKRQFFKFAKKIPAVRRQVETELAKAKNDFETEIKKSNAHLTYSETLPEKGLSKEEILRLVDEH-LKTGHYNWRDGRVSGAVYGYKPDLVELVTEVYGKASYTNPLHADLFPGVCKMEAEVVRMACNLFHGNSAS-CGTMTTGGTESIVMAMKAYRDFAREYKGITRPNIVVPKTVHAAFDKGGQYFNIHVRSVDVDPETYEVDIKKFKRAINRNTILLVGSAPNFPYGTIDDIEAIAALGVKYDIPVHVDACLGSFVVALVRNAGYKLR-PFDFEVKGVTSISADTHKYGFAPKGSSVILYSDKKYKDHQFTVTTDWPGGVYGSPTVNGSRAGGIIAACWATMMSFGYDGYLEATKRIVDTAR-YIERGVRDIDGIFIFGKPATSVIALGSNVFDIFRLSDSLCKLGWNLNALQFPSGIHLCVTDMHTQPGVADKFIADVRSCTAEIMK--DPGQPVVGKMALYGMAQSIPDRSVIGEVTRLFLHSMYYTPSQK------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q05567-1", "uniprot_id": "SGPL_YEAST", "id": "Q05567-1", "name": "Sphingosine-1-phosphate lyase", "aln": "MSGVSNKTVSINGWYGMPIHLLREEGDFAQFMILTINELKIAIHGYLRN-TPWYNMLKDYLFVIFCYKLISNFFYLLKVYGPVRLAVRTYEHSSRRLFRWLLDSPFLRGTVEKEVTKVKQSIEDELIRSDSQLMNFPQLPSNGIPQDDVIEELNKLNDLIPHTQWKEGKVSGAVYHGGDDLIHLQTIAYEKYCVANQLHPDVFPAVRKMESEVVSMVLRMFNAPSDTGCGTTTSGGTESLLLACLSAKMYALHHRGITEPEIIAPVTAHAGFDKAAYYFGMKLRHVELDPTTYQVDLGKVKKFINKNTILLVGSAPNFPHGIADDIEGLGKIAQKYKLPLHVDSCLGSFIVSFMEKAGYKNLPLLDFRVPGVTSISCDTHKYGFAPKGSSVIMYRNSDLRMHQYYVNPAWTGGLYGSPTLAGSRPGAIVVGCWATMVNMGENGYIESCQEIVGAAMKFKKYIQENIPDLNIMGNPRYSVISFSSKTLNIHELSDRLSKKGWHFNALQKPVALHMAFTRLSAH--VVDEICDILRTTVQELKSESNSKPSPDGTSALYGVAGSVKTAGVADKLIVGFLDALYKLGPGEDTATK-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: . . :: ** : . : .: : * * ..: *: . * : :: :: *.*..: :: . . ** :*: ::. :.: *::*:.**:** .* .* . .* . :* **.*:**.: *:*:*:* :. :*:. . : ** *:*****:::* : : * . :**. *:*:.* :.**.*:*.. **.::: * :**: .:: *.:** :** *:*:**:* * : :. :. :*.:*.***:***.*:: ::.:*** :**.* ******.******:******:::* :.. : :*: * . * **:*.**:: ***.*.* ..***::: :* :**:*: :.*: :* : : .:* .: ::*.* ***::.*. ::*..**: : **::* ** * .:*:..* : :: *. :: :* . :: . :. * *:**:* : : :: **..:* . ", "identical_positions": 150, "similar_positions": 195, "identity": "25.04%" }, { "cls_id": "homologset.agr.MGI:1261419", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q69ZL1-1", "uniprot_id": "FGD6_MOUSE", "id": "Q69ZL1-1", "name": "FYVE, RhoGEF and PH domain-containing protein 6", "aln": "MTSAAELKKPPLAPKPKLVGTNNKPPPPPIAPKPDIGSAS-VPRLTKKTKPAIAPKPKVPTNSVVQDIKHPPSKKPTLNLEEREPELPESTGKSNCKDVRDPHSDYILPTCS-CSSGCIHEPRTRETQCVEQLVLEPLGMKENLENSKNGE----SSKRGSSWDSSSEKCRGQSGVVLKASILEEKLKEVLTQ--QRSPCGSPGRHRAPKKPEMNGDHSCTRQIRIEFADVSSSLTGFEKVPAH--HNCHPQLPRDESQTLKTCQDGSAESRGHTDSCEPE----NKR---VASDGISQKTEVKGLGPLEIHLLPYTSKFPTPKPRKTHAAARLRRQKHVDTPGESTEEPGNSNNGSSCLLEDYCLKNNKVSVLRQNALYNQGPVDEVRPANQRALTGDSNSGGQDSVGSQKAVQQQT-------PSLDTDSSLTSDS---SGSGVSPAVDKETTYTQCSTQPLSLPKQVTSACTDQPPATCNPEVSAPPIQKE-----SSSSRIIPKKPQRHSLPAAGVLKKAASEELVEKSS--SGKETNVEKGLHRNYLHHPGPPNHGASASPFDMPNPTSEKPVWKLPHPILPFSGSPEALKRVTLSLNNEPSVSLTKPRAKSLSAVDADRCNKPCKDPPKKTSFKKLINVKLSIGFIKSDFQKIRSKSCQHGDVSAGHPLAREPKGLESDWQGLATGEEKRSKPTKAHSAENCSLESQK--VKSWGQSSAVNGQRAESLDDRILSRHTSCTG-------DFGPEYENVRHYEEIPEYENLPFVMAGRNTPDLGWQN---SSSVEDTDASL---------YEVEEPYNAPDGQLQLDPRHQPCSSGTSQEGKDALHLGLSDLPSDEE----VINSSDEDDVSSESSKGEPDPLEDKQDEDAGMKSKVHHIAKEIMSSEKVFVDVLKLLHIDFRGAVAHASRQLGKPVIEDRILNQILYYLPQLYELNRDLLKELEERMLTWTEQQRIADIFVKKGPYLKMYSTYIKEFDKNVALLDEQCKKNPGFAAVVREFEMSPRCANLALKHYLLKPVQRIPQYRLLLTDYLKNLLEDSVDHRDTQDALAVVIEVANHANDTMKQGDNFQKLMQIQYSLSGHHEIVQPGRVFLKEGTLMKLSRKVMQPRMFFLFNDALLYTTPMQSGMYKLNNMLSLAGMKVRKPTQEAYQNELKIESVERSFILSASSAAERDDWLEAISSSIEEYAKKRITFCPSRSLDE-DSERKEEVSPLGAKAPIWIPDTRATMCMICTSEFTLTWRRHHCRACGKIVCQACSSNKYGLDYLKGQLARVCEHCFQELQKLDHQLSPRVGSPGNHKSPSSALSSVLHSIPSGRKQKKIPAALKEVSANTEDSTMSGYLYRSKGSKKPWKHLWFVIKNKVLYTYAASEDVAALESQPLLGFTVTLVKDENSESKVFQLLHKGMVFYVFKADDAHSTQRWID-AFQEGTVL------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K7L6-1", "uniprot_id": "A0A0G2K7L6_RAT", "id": "A0A0G2K7L6-1", "name": "", "aln": "-FFPLELKKPPLAPKPKLVGTNNKSPPPPIAPKPDIGNAS-VPRLT-KTKPAIAPKPKVLTNSDVQDVKDQPSKKLTLNLEEREPELPESTGKFNCKDVGDAHGDYIFPTCS-CSSGCTHEPRTRENLCAEQLVLEPLGMKEHLENGKNGE----SSKRGSRWNSSREKCRSQSGVVLKASIFEEKLKEVLTQPRSRSPSSSPRKHRCPNKPEMNGDHSCARQVRIEFADTSSSQSSFGKAP----HSCHTQPPRDKSQNLQTCQDGSAESLGPFHSCELE----GKR---GCSGGTSQKSEVQGLGPVEIHLLPYTSKFPTPKPRRTHAAR-LRRQKHVDTPSESTEEPESSNNGSSCLHED-SLKNNKVSVLHQNALSNQGPVDEVRPGNKKALTRESNSDRQDSVSSQKAVQHETSSFEKVAPSLDTDSSLTSDSTVEDGSDVLPAVDRETAFIQCSPQPLSLPKQVKLACAEQQPTTCNREVSVPQIQKE-----SSS-RIVPKKPQRHSLPAAGVLKKAASEELVEKNS--SSKETNSEKGLQRNHLQHLGPSNHGMSPSSFDMPNPTSEKPVWKLPHPILPFPGSPEALKRVTLSLNNEPSISLTKPRAKSLSAVDMDRCSKPCKEPPKKTTFKKLINVKLSIGFIKSDFHKFKSKNCQHGDVSTGHSLGREPKGLENNWQGLATGEEKKSKPIKAYSEENCSLESQK--VKSWSQSSATNGQRAESLDDQMLSRHASCQASST---SDCGPEYENVRHYEEIPEYENLPFVMARGNPPELGWQN---SSSVEDTDVSL---------YEVEEPYDAPDGQLQLDPRHQPCSSGRCQDRQDELHL---DLPSDEE----VINSSDEDDVSSESSKGEPDPLEDKQDEDAGMKSKVHHIAKEIMSSEKVFVDVLKLLHIDFRGAVAHASRQLGKPVIEDRILNQILYYLPQLYELNRDLLKELEERMLSWAEQQRIADIFVKKGPYLKMYSMYIKEFDKNIALLDEQCKKNSGFATVVREFEMSPRCANLALKHYLLKPVQRIPQYRLLLTDYLKNLLEDSVDHRDTQDALAVVIEVANHANDTMKQGDNFQKLMQIQYSLSGHHEIVQPGRVFLKEGILMKLSRKVMQPRMIFLFNDALLYTTPMQSGMYKLNNMLSLAGMKVRKPTQEAYQNELKIESVERSFILSASSASERDDWLEAISRAIEEYAKKRITFCPSRSLDE-DSERKEEVSPLGAKAPIWIPDTRATMCMICTSEFTLTWRRHHCRACGKIVCQACSSNKCGLDYLKGQPARVCELCFQELQKLDHQLSPRIGSPGNHKSPSSALSSVLHSIPSGRKQKKIPAALKEVSANTEDSTMSGYLYRSKGSKKPWKHLWFVIKNKVLYTYAASEDVAALESQPLLGFTVAQVKDEHSDPRVFQLLHKGLLFYVFKADDAHSTQSTLPLSFQKGLVLFSQLWS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6ZV73-1", "uniprot_id": "FGD6_HUMAN", "id": "Q6ZV73-1", "name": "FYVE, RhoGEF and PH domain-containing protein 6", "aln": "MTSAAEIKKPPVAPKPKFVVANNKPAPPPIAPKPDIVISS-VPQSTKKMKPAIAPKPKVLKTSPVREIGQSPSRKIMLNLEGHKQELAESTDNFNCKYEGNQSNDYISPMCS-CSSECIHKLGHRENLCVKQLVLEPLEMNENLENSKIDETL--TIKTRSKCDLYGEKAKNQGGVVLKASVLEEELKDALIH--QMPPFISAQKHRPTDSPEMNGGCNSNGQFRIEFADLSPSPSSFEKVPDH--HSCHLQLPSDECEHFETCQDDSEKSNNCFQSSELEALENGKRSTLISSDGVSKKSEVKDLGPLEIHLVPYTPKFPTPKPRKTRTAR-LLRQKCVDTPSESTEEPGNSDSSSSCLTEN-SLKINKISVLHQNVLCKQEQVDKMKLGNKSELNMESNSDAQDLVNSQKAMCNETTSFEKMAPSFDKDSNLSSDSTTVDGSSMSLAVDEGTGFIRCTVS-MSLPKQLKLTCNEHLQSGRNLGVSAPQMQKESVIKEENSLRIVPKKPQRHSLPATGVLKKAASEELLEKSSYPSSEEKSSEKSLERNHLQHLCAQNRGVS-SSFDMPKRASEKPVWKLPHPILPFSGNPEFLKSVTVSSNSEPSTALTKPRAKSLSAMDVEKCTKPCKDSTKKNSFKKLLSMKLSICFMKSDFQKFWSKSSQLGDTTTGHLSSGEQKGIESDWQGLLVGEEKRSKPIKAYSTENYSLESQKKRKKSRGQTSAANGLRAESLDDQMLSRESSSQAPYKSVTSLCAPEYENIRHYEEIPEYENLPFIMAIRKTQELEWQN---SSSMEDADANV---------YEVEEPYEAPDGQLQLGPRHQHSSSGASQEEQNDLGLG--DLPSDEEE---IINSSDEDDVSSESSKGEPDPLEDKQDEDNGMKSKVHHIAKEIMSSEKVFVDVLKLLHIDFRDAVAHASRQLGKPVIEDRILNQILYYLPQLYELNRDLLKELEERMLHWTEQQRIADIFVKKGPYLKMYSTYIKEFDKNIALLDEQCKKNPGFAAVVREFEMSPRCANLALKHYLLKPVQRIPQYRLLLTDYLKNLIEDAGDYRDTQDALAVVIEVANHANDTMKQGDNFQKLMQIQYSLNGHHEIVQPGRVFLKEGILMKLSRKVMQPRMFFLFNDALLYTTPVQSGMYKLNNMLSLAGMKVRKPTQEAYQNELKIESVERSFILSASSATERDEWLEAISRAIEEYAKKRITFCPSRSLDEADSENKEEVSPLGSKAPIWIPDTRATMCMICTSEFTLTWRRHHCRACGKIVCQACSSNKYGLDYLKNQPARVCEHCFQELQKLDHQHSPRIGSPGNHKSPSSALSSVLHSIPSGRKQKKIPAALKEVSANTEDSSMSGYLYRSKGNKKPWKHFWFVIKNKVLYTYAASEDVAALESQPLLGFTVIQVKDENSESKVFQLLHKNMLFYVFKAEDAHSAQKWIE-AFQEGTIL------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5RH33-1", "uniprot_id": "Q5RH33_DANRE", "id": "Q5RH33-1", "name": "", "aln": "------MKKPPVAPKPKLVPLH-KPSPPPIAPKPEILLPSPSPTAHKRGKPAVAPKPCLLK---------APQKPVQARQDHCKNQHPPVSKNGGPALLSSNLSHYIIPPCNKVCHLANNKSNDSKEISREATLTTEVGVFKEGDSPKEHLFSNDTWEHTARSEHVQEQVPTDSTQMSTEAQDETNSPSVEKDQTSTQVLTSDHIPRHCPTEPLQERSSEVKETGNVFSSCTSDSVGVPAPPSKPLPVPHPRRPRRALLRQNVVEIAPSDTQADIPTETPEN---------AQSDGLQETPKNTTCHSHTSTLQNACCPKEDIENTDTDSSTKSDPLHKVDSFYNAQTEDMPSDLDS----THYSVPTNGATLASMDTAVEDGSQPPAPPPRQKSLPQMVDSLCKASTSVDN-------------LLLHCQSDLQEVTSNDEDAESDDEDDGAYGDFARYPITRSLPKQIKLSCGSQVIA-----ITKPYIDGD-----EKSPKVMPKKPQRNSLPASVALRKQGTPPPLPNSN----------------------------PPVFGELPAPPQEKPSWRVALPSIPLFSRNQPTRSNSQPQAGVVGSVFVKQRAKSFSSADLQRVDN---------------GSEASEQLARSDQTRRSLR-----------------KLLELRVCARLLPKLLRSGQSLDCTRTDSEYEEHK----------AVPANQVTSGDDEEAQGDS---------EADCGVEYENVPLYEEIPEYMNLPWVYSNQDADTDVYEVQEPSMTVEFVNAFLTFISHWLVCDELSVPAKQRCAELAVGFQMHRTLNQACGRVFGNVSMLPTNIYMSADLSEDGLSSNEEDGDSSDSSKEDMRHSKDKEEVERAKRNKVVHIAMEIMSSEKVFVDVLKLLHIDFRDAVAKATRASGKPLVEEKVLNQILYYLPQLYELNKDLLKELEERVAHWSDHQRLADIFVQKGPYLKMYSTYIREFDRNVALLDEQCRKNPPFSSVVRQFETSPRCASLALKHYLLKPVQRIPQYQLLLTDYLKNLPEDSSDYKDTQTALSVVKEVANHANDIMKQGDNFQKLMQVQYSLNGHHEIVQPGRVFLKEGTLMKLSRKVMQPRMFFLFNDILLYTTPVQSGQYKVNSMLSLAGMKVSKPSQEAYQNELNIESVERSFILSANSATERDEWLEAIATAIDDYTRKKISFFSSRSQEL--EGISDDGLPLGSKAPIWIPDLRTTMCMICTCEFTLTWRRHHCRACGKVVCQACSSNKFYLEYLKNQLARVCDHCYIKLQHKGDQSNVTFSPSG--RGSTFAFS---------RKQKKIPSALKEVSANTENSSMSGYLHRSKGHKKPWKRLWFVIKNKVLYTYAASEDVAALESQPLLGFFLREEKTGPAQKLQFKLYHKNTLYYIFRAEDIPTAQRWIE-AFQEAMIL------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :****:*****:* : *..********:* .* * : ***:**** : . *.: . : : : . : : . . ..** * *. . . :: : . : : : : :. :. * : : : : *: :. : . : * : .. . . * * . :: . : *:. :.. .. * * : * :. : . .: : * *.* .:..: . * : * :: : **: :: * *: .* . .: * :: :. :: .: * :* : .. :: :. :*.* . : ..: * *****:. :* .: : :: * :: : ..* :::******:****: .*:* .: : :.. . ::* ..*** *::. * :*: . : : : . . . :.* ****:*: * :: : . : * : :** : : * :* . : :* : : . *.:* *. . :. * **. . .: . ****: ******* ***:: : .. :: * ::* .:. : *:. * . .:* :. : : . . . : : :: . : :.*.:**. **:*** : :**:: : . :.** *** *********************.***:*:* ***::*:::***************:*********: *:::**:*****:********* **:***:*:*******:**. *::***:** *****.*****************:********** **: *::*** **:** ******** ************:****.**************** *************:***** ******:*** **:*.********* **:********:************.**:***:*****: :*::*::*:*:* .*** : . .:: ***:******** *:*******.****************:********* *:***.* ****: *: :**: ..* . ....* :..: *:* *******:**********:*:*****:**** *****::***************************** : * :: *:* **. ::*:*:*:* ::* : :**:. :* ", "identical_positions": 526, "similar_positions": 336, "identity": "35.88%" }, { "cls_id": "homologset.agr.MGI:1261422", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q66H12-1", "uniprot_id": "NAGAB_RAT", "id": "Q66H12-1", "name": "Alpha-N-acetylgalactosaminidase", "aln": "MLQKTVLLLALVAQVLMLENGLLRTPPMGWLAWERFRCNINCEEDPKNCISERLFMEMADRLAQDGWRDLGYVYLNIDDCWIG-GRDATGRLIPDPKRFPHGIAFLADYAHSLGLKLGIYEDMGKMTCMGYPGTTLDKVELDAATFAEWKVDMLKLDGCYSTPKERAEGYPKMAAALNATGRPIAFSCSWPAYEGGLPPKVNYTEVAGTCNLWRNYKDIQDSWKSVLSILDWFVKHQDILQPVSGPGHWNDPDMLLIGNFGLSFDESRAQMALWTVLAAPLFMSTDLRTISPQNIDILQNPLLIKINQDPLGIQGRLIFKSKSHIEVFKRNLSDDAS-----ALVFFSRRTD-MPYHFHCSLLELNYPKGSVYEGQNVFTGDIISGLHPETNFTVIINPSGVVMWYLYPVKGLGIYTMMSQL----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QWR8-1", "uniprot_id": "NAGAB_MOUSE", "id": "Q9QWR8-1", "name": "Alpha-N-acetylgalactosaminidase", "aln": "MLQKTVLLLALVAQVLMLENGLLRTPPMGWLAWERFRCNIDCVEDPKNCISERLFMEMADRLAQDGWRDLGYVYLNIDDCWIG-GRDASGRLIPDPKRFPHGIAFLADYAHSLGLKLGIYEDMGKMTCMGYPGTTLDKVELDAETFAEWKVDMLKLDGCFSSSRERAEGYPKMAAALNATGRPIAFSCSWPAYEGGLPPKVNYTEVSRVCNLWRNYKDIQDSWKSVLSILDWFVRHQDVLQPVAGPGHWNDPDMLLIGNFGLSFDESRAQMALWTVLAAPLLMSTDLRTISPQNMDILQNPLMIKINQDPLGIQGRRILKSKSHIEVFKRYLSNQAS-----ALVFFSRRTD-MPFRFHCSLLELNYPKGRVYEGQNVFTGDIFSGLQTEVNFTVIINPSGVVMWYLYPIKDLGISTMMSHW----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P17050-1", "uniprot_id": "NAGAB_HUMAN", "id": "P17050-1", "name": "Alpha-N-acetylgalactosaminidase", "aln": "MLLKTVLLLGHVAQVLMLDNGLLQTPPMGWLAWERFRCNINCDEDPKNCISEQLFMEMADRMAQDGWRDMGYTYLNIDDCWIG-GRDASGRLMPDPKRFPHGIPFLADYVHSLGLKLGIYADMGNFTCMGYPGTTLDKVVQDAQTFAEWKVDMLKLDGCFSTPEERAQGYPKMAAALNATGRPIAFSCSWPAYEGGLPPRVNYSLLADICNLWRNYDDIQDSWWSVLSILNWFVEHQDILQPVAGPGHWNDPDMLLIGNFGLSLEQSRAQMALWTVLAAPLLMSTDLRTISAQNMDILQNPLMIKINQDPLGIQGRRIHKEKSLIEVYMRPLSNKAS-----ALVFFSCRTD-MPYRYHSSLGQLNFTGSVIYEAQDVYSGDIISGLRDETNFTVIINPSGVVMWYLYPIKNLEMSQQ--------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IJL2-1", "uniprot_id": "A0A0R4IJL2_DANRE", "id": "A0A0R4IJL2-1", "name": "Alpha-galactosidase", "aln": "MWSACVLFLAFSSAALALDNGLMRTPPMGWLAWERFRCDIDCQNDPYNCISEQLFMDMADRLSEDGWKELGYVYVNIDDCWSSKDRDAQGRLQPDPKRFPRGIPHLAQYVHDRGLKLGIYGDMGTLTCGGYPGTTLDKIETDAQTFADWGIDMLKLDGCYSNSSYQEQGYPMMSKALNATGRPIGYSCSWPAYQGGLPPKVNYTLLGQICNLWRNYDDIQDSWDSVMGIVDWFFDNQDALQPAAAPGQWNDPDMLIIGDFSLSLDQSRAQMALWSIMAAPLFMSNDLRTISSAARSVLQNKAVISINQDPLGIQGRRLLKEKSGIQVFQRPLSKGAS-----ALVFFSRRSD-MPYRYTTSLKTLGYQPG-VFEVFDVFSEQRLPELKDSTQFTVSINPSGVVMWYIYPAADRWKEAEFEGFSKKLIGPKFHRHANEVDAPLVL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VL27-1", "uniprot_id": "Q9VL27_DROME", "id": "Q9VL27-1", "name": "Alpha-galactosidase", "aln": "MLATLWIILLSSTFGKCLDNGLAKTPPMGWLSWERFRCNTDCVNDPDNCISEQLFQTMTDIVVADGYASVGYEYINIDDCWLEKHRSHDGKLVADRKRFPNGIKALSDYIHSRGLKFGIYEDYGNYTCAGYPG-IIGYEEKDALQFADWNVDYVKLDGCYALPYDMDHGYSTFGRLLNSTGKSMVYSCSWPVYQIYAGIQPNYSAIQTHCNLWRNYDDIQDSWASVENIIDYYGNNQDVIAPNAGPGHWNDPDMLIIGNFGLSYEQAKTQFAIWSILAAPLLMSVDLRTIRPQFKHILQNRKIIAVDQDPLGIQGRRIYKHKG-IEIWSRPIGPLYQNFYSYAIAFVNRRTDGTPSDISVTLKELGLINFSGYRVEDLYENVDYGVLYPNTKIKVKVNPSGVVMLKGEVQYPVDL-----------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* ::* : *:*** :*******:******: :* :** *****:** *:* : **: .:** *:****** *. *:* .* ****.** *::* *. ***:*** * *. ** **** :. ** **:* :* :*****:: . .**. :. **:**:.: :*****.*: : **: : *******.****** ** .*:::: :** : * :.**:*******:**:*.** :::::*:*:*:::****:** ***** . :*** :* ::********* : * *. *::: * :. . *:.*.. *:* * :* *. :. ::: * ..::.* :******* ", "identical_positions": 174, "similar_positions": 103, "identity": "39.19%" }, { "cls_id": "homologset.agr.MGI:1261423", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JHX4-1", "uniprot_id": "CASP8_RAT", "id": "Q9JHX4-1", "name": "Caspase-8", "aln": "MDFHSCLYDIAERLGNEELAALKFLCLDHIPQKKQESINDVLVLFQRLQEEGMLEEDNLSFLKELLFHISRRDLLSRVLKSSPEEMVRELQVLGKAQVSAYRVMLFKLSEDMDKEDLKSFKFLLITEIPKCKLQDNSSLLDIFVEMEKRTILAENNLVTLKSICFRVNRSLLGRIDDYERSSTERRMSTEGG-EELPVSVLDEVTIKMQDMWDSPGEQESESLNSDNVYQMKSKPRGYCLIFNNNNFSKAREDIPKLSNMRDRKGTNYDEEALSKTFKELHFEIVSFSDCTASQIHEVLVSYQSKDHKGKDCFICCILSHGDKGIVYGTDGKEASIYELTSYFTGSKCPSLAGKPKIFFIQACQGNNFQKAVPVPDETGLEQ-EHVLEEDSSSYKN-YIPDEADFLLGMATVKNCVSYRDPTRGTWYIQSLCQSLRERCPRGEDILSILTGVNYDVSNKDNPRNMGKQMPQPIFTLRKKLFFPPN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O89110-1", "uniprot_id": "CASP8_MOUSE", "id": "O89110-1", "name": "Caspase-8", "aln": "MDFQSCLYAIAEELGSEDLAALKFLCLDYIPHKKQETIEDAQKLFLRLREKGMLEEGNLSFLKELLFHISRWDLLVNFLDCNREEMVRELRDPDNAQISPYRVMLFKLSEEVSELELRSFKFLLNNEIPKCKLEDDLSLLEIFVEMEKRTMLAENNLETLKSICDQVNKSLLGKIEDYERSSTERRMSLEGR-EELPPSVLDEMSLKMAELCDSPREQDSESRTSDKVYQMKNKPRGYCLIINNHDFSKAREDITQLRKMKDRKGTDCDKEALSKTFKELHFEIVSYDDCTANEIHEILEGYQSADHKNKDCFICCILSHGDKGVVYGTDGKEASIYDLTSYFTGSKCPSLSGKPKIFFIQACQGSNFQKG--VPDEAGFEQQNHTLEVDSSSHKN-YIPDEADFLLGMATVKNCVSYRDPVNGTWYIQSLCQSLRERCPQGDDILSILTGVNYDVSNKDDRRNKGKQMPQPTFTLRKKLFFPP-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14790-1", "uniprot_id": "CASP8_HUMAN", "id": "Q14790-1", "name": "Caspase-8", "aln": "MDFSRNLYDIGEQLDSEDLASLKFLSLDYIPQRKQEPIKDALMLFQRLQEKRMLEESNLSFLKELLFRINRLDLLITYLNTRKEEMERELQTPGRAQISAYRVMLYQISEEVSRSELRSFKFLLQEEISKCKLDDDMNLLDIFIEMEKRVILGEGKLDILKRVCAQINKSLLKIINDYEEFSKERSSSLEGSPDEFSN---GEELCGVMTISDSPREQDSESQTLDKVYQMKSKPRGYCLIINNHNFAKAREKVPKLHSIRDRNGTHLDAGALTTTFEELHFEIKPHDDCTVEQIYEILKIYQLMDHSNMDCFICCILSHGDKGIIYGTDGQEAPIYELTSQFTGLKCPSLAGKPKVFFIQACQGDNYQKG--IPVETDSEE-QPYLEMDLSSPQTRYIPDEADFLLGMATVNNCVSYRNPAEGTWYIQSLCQSLRERCPRGDDILTILTEVNYEVSNKDDKKNMGKQMPQPTFTLRKKLVFPSD", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** ** *.*.*..*:**:****.**:**::***.*:*. ** **:*: ****.**********:*.* *** *. *** ***: ..**:*.*****:::**::.. :*:****** **.****:*: .**:**:*****.:*.*.:* ** :* ::*:*** *:***. *.** * ** :*:. .* : : *** **:*** . *:*****.********:**::*:****.:.:* .::**:**. * **:.**:****** ...***..:*:*:* ** **.. **************::*****:**.**:*** *** *****:****:********.*:**. :* *:. *: : ** * ** :. ***************:******:*..*****************:*:***:*** ***:*****: :* ******* *******.**. ", "identical_positions": 293, "similar_positions": 116, "identity": "60.41%" }, { "cls_id": "homologset.agr.MGI:1261425", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5HZJ0-1", "uniprot_id": "RNC_MOUSE", "id": "Q5HZJ0-1", "name": "Ribonuclease 3", "aln": "-MQGNTCHRMSYHPGRGCPRGRGGHGARPSAPAFRPQNLRLLHPQQPPAQYQYEPPSAPSSSYSNSQAPSFMPPRPDFVPYPPPAAPSAQGPLPPCPVRPPYPNHQMRHPFPVPPCFPPMPPPMPCPNNPPASGAPPGQGTFPFMVPPPSMPHPPPPPVMPQQVNYQYPPGYSHS-FPPPGFNSYQNNSSSFPPSANSSSTPHFRHLPPYSLPKAQNERRSPERLKHYDDHRHRDHSHGRGERHRSLERRERGRSPERRRPESRYRSDYDRGRTPPPRHRSYERSRERDRERHRHREARRSPSLERSYKKEYKRSGRSYALPVAPEPAGCTPELPGEMIKTTESWAPPPENVNHRSPSREKKRARWEEEKDRWSDSQGSGKEKNYTSIKEKEAEEVPPEKTEEEEEELLKPVWIRCTHSESYYSSDPMDQVGDSTVVGTSRLRDLYDKFEEELGNRQEKAKAARPPWEPPKTKLDEDLESSSESECETDDDSTCSSSSDSEVFDVIAEIKRKKAHPDRLHDELWYNDPGQMNDGPLCKCSAKARRTGIRHSIYPGEEAIKPCRPMTNNAGRLFHYRITVSPPTNFLTDRPTVIEYDDHEYIFEGFSMFAHAPLTNIPLCKVIRFNIDYTIHFIEEMMPENFCVKGLELFSLFLFRDILELYDWNLKGPLFEDSPPCCPRFHFMPRFVRFLPDGGKEVLSMHQILLYLLRCSKALVPEEEIANMLQWEELEWQKYAEECKGMIVTNPGTKPSSVRIDQLDREQFNPEVITFPIIVHFGIRPAQLSYAGDPQYQKLWKSYVKLRHLLANSPKVKQTDKQKLAQREEALQKIRQKNTMRREVTVELSSQGFWKTGIRSDVCQHAMMLPVLTHHIRYHQCLMHLDKLIGYTFQDRCLLQLAMTHPSHHLNFGMNPDHARNSLSNCGIRQPKYGDRKVHHMHMRKKGINTLINIMSRLGQDDPTPSRINHNERLEFLGDAVVEFLTSVHLYYLFPSLEEGGLATYRTAIVQNQHLAMLAKKLELDRFMLYAHGPDLCRESDLRHAMANCFEALIGAVYLEGSLEEAKQLFGRLLFNDPDLREVWLNYPLHPLQLQEPNTDRQLIETSPVLQKLTEFEEAIGVIFTHVRLLARAFTLRTVGFNHLTLGHNQRMEFLGDSIMQLVATEYLFIHFPDHHEGHLTLLRSSLVNNRTQAKVAEELGMQEYAITNDKTKRPVALRTKTLADLLESFIAALYIDKDLEYVHTFMNVCFFPRLKEFILNQDWNDPKSQLQQCCLTLRTEGKEPDIPLYKTLQTVGPSHARTYTVAVYFKGERIGCGKGPSIQQAEMGAAMDALEKYNFPQMAHQKRFIERKYRQELKEMRWEREHQEREPEEAEDIKK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E9PTR3-1", "uniprot_id": "E9PTR3_RAT", "id": "E9PTR3-1", "name": "Ribonuclease 3", "aln": "-MQGNTCHRMSYHPGRGCPRGRGGHGARPSAPTYRPQNLRLLHPQQPPAQYQYEPPSAPSSSFSNSQAPNFMPPRPDFVPYPPPVAPSAQGPLPPCPVRPPYPNHQMRHPFPVPPCFPPMPPPMPCPNNPPVSGAPPGQGTFPFMVPPPSMPHPPPPPVMPQQVNYQYPPGYSHS-FPPPNFNSFQNNSSSFPPSANNSSTPHFRHLPPYSLPKAQSERRSPERLKHYDDHRHRDHSHGRGERHRSLERRERGRSPERRRPESRYRSEYDRGRTPPPRHRSYERSRERERERHRHRENRRSPSLERAYKKEYKRSGRSYGLPVTPEPAGCTAELPGEIIKNTDSWAPPQENVNHRSPSREKKRARWEEEKDRWSDSQSSGKEKSYTSIKEKEPEEAPPEKTEEEDEELLKPVWIRCTHSESYYSSDPMDQVGDSTVVGTSRLRDLYDKFEEELGNRQEKAKAARPPWEPPKTKLDEDLESSSESECETDEDSTCSSSSDSEVFDVIAEIKRKKAHPDRLHDELWYNDPGQMNDGPLCKCSAKARRTGIRHSIYPGEEAIKPCRPMTNNAGRLFHYRITVSPPTNFLTDRPTVIEYDDHEYIFEGFSMFAHAPLTNIPLCKVIRFNIDYTIHFIEEMMPENFCVKGLELFSLFLFRDILELYDWNLKGPLFEDSPPCCPRFHFMPRFVRFLPDGGKEVLSMHQILLYLLRCSKALVPEEEIANMLQWEELEWQKYAEECKGMIVTNPGTKPSSVRIDQLDREQFNPEVITFPIIVHFGIRPAQLSYAGDPQYQKLWKSYVKLRHLLANSPKVKQTDKQKLAQREEALQKIRQKNTMRREVTVELSSQGFWKTGIRSDVCQHAMMLPVLTHHIRYHQCLMHLDKLIGYTFQDRCLLQLAMTHPSHHLNFGMNPDHARNSLSNCGIRQPKYGDRKVHHMHMRKKGINTLINIMSRLGQDDPTPSRINHNERLEFLGDAVVEFLTSVHLYYLFPSLEEGGLATYRTAIVQNQHLAMLAKKLELDRFMLYAHGPDLCRESDLRHAMANCFEALIGAVYLEGTLEEAKQLFGRLLFNDPDLREVWLNYPLHPLQLQEPNTDRQLIETSPVLQKLTEFEEAIGVIFTHVRLLARAFTLRTVGFNHLTLGHNQRMEFLGDSIMQLVATEYLFIHFPDHHEGHLTLLRSSLVNNRTQAKVAEELGMQEYAITNDKTKRPVALRTKTLADLLESFIAALYIDKDLEYVHTFMNVCFFPRLKEFILNQDWNDPKSQLQQCCLTLRTEGKEPDIPLYKTLQTVGPSHARTYTVAVYFKGERIGCGKGPSIQQAEMGAAMDALEKYNFPQMAHQKRFIERKYRQELKEMRWEREHQEREPDEAEDIKK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NRR4-1", "uniprot_id": "RNC_HUMAN", "id": "Q9NRR4-1", "name": "Ribonuclease 3", "aln": "MMQGNTCHRMSFHPGRGCPRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPSTTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPMPPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHYDDHRHRDHSHGRGERHRSLDRRERGRSPDRRRQDSRYRSDYDRGRTP-SRHRSYERSRERERERHRHRDNRRSPSLERSYKKEYKRSGRSYGLSVVPEPAGCTPELPGEIIKNTDSWAPPLEIVNHRSPSREKKRARWEEEKDRWSDNQSSGKDKNYTSIKEKEPEETMPDKNEEEEEELLKPVWIRCTHSENYYSSDPMDQVGDSTVVGTSRLRDLYDKFEEELGSRQEKAKAARPPWEPPKTKLDEDLESSSESECESDEDSTCSSSSDSEVFDVIAEIKRKKAHPDRLHDELWYNDPGQMNDGPLCKCSAKARRTGIRHSIYPGEEAIKPCRPMTNNAGRLFHYRITVSPPTNFLTDRPTVIEYDDHEYIFEGFSMFAHAPLTNIPLCKVIRFNIDYTIHFIEEMMPENFCVKGLELFSLFLFRDILELYDWNLKGPLFEDSPPCCPRFHFMPRFVRFLPDGGKEVLSMHQILLYLLRCSKALVPEEEIANMLQWEELEWQKYAEECKGMIVTNPGTKPSSVRIDQLDREQFNPDVITFPIIVHFGIRPAQLSYAGDPQYQKLWKSYVKLRHLLANSPKVKQTDKQKLAQREEALQKIRQKNTMRREVTVELSSQGFWKTGIRSDVCQHAMMLPVLTHHIRYHQCLMHLDKLIGYTFQDRCLLQLAMTHPSHHLNFGMNPDHARNSLSNCGIRQPKYGDRKVHHMHMRKKGINTLINIMSRLGQDDPTPSRINHNERLEFLGDAVVEFLTSVHLYYLFPSLEEGGLATYRTAIVQNQHLAMLAKKLELDRFMLYAHGPDLCRESDLRHAMANCFEALIGAVYLEGSLEEAKQLFGRLLFNDPDLREVWLNYPLHPLQLQEPNTDRQLIETSPVLQKLTEFEEAIGVIFTHVRLLARAFTLRTVGFNHLTLGHNQRMEFLGDSIMQLVATEYLFIHFPDHHEGHLTLLRSSLVNNRTQAKVAEELGMQEYAITNDKTKRPVALRTKTLADLLESFIAALYIDKDLEYVHTFMNVCFFPRLKEFILNQDWNDPKSQLQQCCLTLRTEGKEPDIPLYKTLQTVGPSHARTYTVAVYFKGERIGCGKGPSIQQAEMGAAMDALEKYNFPQMAHQKRFIERKYRQELKEMRWEREHQEREPDETEDIKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q02555-1", "uniprot_id": "RNT1_YEAST", "id": "Q02555-1", "name": "Ribonuclease 3", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGSKVAGKKKTQNDNKLDNENGSQQRENINTKTLLKG-------NLKISNYKYLEVIQLEHAVTK----------LVESYNKIIELSPNLVAYN------EAVNNQDRVPVQILPSLSRYQLKLAAELKTLHDLKKDAILTE---------ITDYENEFDTEQKQPILQEIS---------------------------------------------KADMEKLEKLEQVKREKREKIDVNVYENLNEKEDEEEDEGEDSYDP------------------TKAGDIVKATKWP------------PKLPEIQDLAIRAR-----VFIHKSTIKDKVYLSGS-------------------------------------------------------------------------------------------------------EMIN------------AHNERLEFLGDSILNSVMTLIIYNKFPDYSEGQLSTLRMNLVSNEQIKQWS--------IMYNFHEKLKTNFDLKDENSN---------FQNGKLKLYADVFEAYIGG---------------LMEDDPRNN-------------------LPKIRKWLRKLAKPVIEEAT-------------------------------------RNQVALEKTDKLDMNAKRQLYSLIGYASLRLHYVTVKKPTAVDPNSIVECRVG---------------------------------------------------------------------------------DGTVLGTGVGRNIKIAGIRAAENALRDKKMLDFYAKQRAAIPRSESVLKDP--SQKNKKRKFSDTS----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. . *:*. : ::*.:* :: ::* .* * .:: * * *.*: :.:*: *.. .::: *.:: *: *... :.*: :* . :::: :: :.:: : : .: : * : :* : * *:::: . *:* : *:** * :. * : . . : .. . :: ..:.::* : *** . * **: : :. : * : :*.*:: :* :. * :::. **********:::: : :: :* **. .** *:* * :*.*::: : ::* . .* : **:. :* : :*.*: ::* : . * ::*..: : * . :* **:.. .:. ..:::* ::. :: .:: :: . :* . : ..*:*.*: .:::.: . .* :* * * .*: * : ** :**.. :: :: ::* : .. **: .:::::*: .::. ", "identical_positions": 94, "similar_positions": 211, "identity": "6.84%" }, { "cls_id": "homologset.agr.MGI:1261426", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A2BFG8-1", "uniprot_id": "A2BFG8_MOUSE", "id": "A2BFG8-1", "name": "", "aln": "MDLVTYDDVHVNFTQEEWALLDASQKSLYKGVMVETYRNLT------------------------------AIGYSWEEHT-----------------------------------IEDHFQTSRSHGR--------------------------------------------HERSS-----------------SAEQHSEFIQCGKAFAYQS--------HSQR-----------------HERIHNGEK----------------------------HCECNQCGKDFGTRSILQR-LKRTHTGEKPYECNHCGKAFVESCTLQIHKRKHTGEKPYECNQCGKAFAQSCHLRIHKRTHTGEKPYECKQCGKAFAVSSHLG----------------------------IHKRTHTGEKP--------------------------------------------------------YECKQCGKAFAVSSHLGIHKRTHTGEKPYECKQCDKAFVRRGKLQIHKRTHTGEKPYECKQCGKAFAHSGTLQIHKRTHTGEKPYECYQCGKAFATSCHLRRHNRTHSGEKQYECNQCGKAFASSSDLQKHKRTHTGDKPYECKQCGKAFASSSDLQKHKRTHTGEKPYECKQCGKAFAES----------------------------STLQRHKRTHTGEKPYECKQCGKAFARSCHLQIHKRTHTGEKPYECKQCGKAFARSSHLRIHKRTHTGERPYECN---------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AZW3-1", "uniprot_id": "A0A8I6AZW3_RAT", "id": "A0A8I6AZW3-1", "name": "", "aln": "-NALTYDDVHVNFTREEWILLNPSQKNLYKDVILETYRNLT------------------------------AIGYNWEDHN-----------------------------------IEEHCQSSRRHTR--------------------------------------------HEGSP-----------------PGEKPSEYTQCGKALAYHS--------YHQR-----------------HERIHTGEKPYEGSQCGEFAYQSS-LQIHKRTCTKEKPYKCNQCDKAFSQHGYLRT-HKRTHTGQKPYECNQCGKAFVYRCYLRIHERTHTGEKPYKCNQCDKAYSQHSHLQIHRRTHTGEKPYKCNQCDKAFACPSHFQRHERIHAGEKPYKCNLCDKAFACQSSLRIHKRTHTGEKPYECNYCGKAFAYHGQLKVHKRSHAGEKSYEDIQYHEVFAYHSSLQIYKRTYGGERLYECNQCGKVFACPSNLQIHNRTHTGEKPYKCNQCDKTFSQYNNLQIHKRTHTGEKPYECNYCGKAFAYHGYLHIHKRMHTGEKPYQCNECDKSFSQQSYFQIHKKTHTGEKPYECKQCGKSFASHGQLQRHERIHTGEKPYKCNECDKSFSQQSYFQIHKKTHTGEKPYECKQCGKSFAYHGQLQRHEKVHIEEKPYKCSDCGKAFTCRFNLQRHKRTHTGEKPYECNQCGKAFAYHDYLQIHKRTHTGEKPYECSQCGKSFLCHSSLRIHRRIHIGDKPHECDRS-KAFARHNDLQRHETNHTKK-KPYK------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P52737-1", "uniprot_id": "ZN136_HUMAN", "id": "P52737-1", "name": "Zinc finger protein 136", "aln": "MDSVAFEDVDVNFTQEEWALLDPSQKNLYRDVMWETMRNLA------------------------------SIGKKWKDQN-----------------------------------IKDHYKHRGRNLRSHMLERLYQT----------------------------------KDGSQRGGIFSQFANQNLSKKIPGVKLCESIVYGEVSMGQS--------SLNR-----------------HIKDHSGHEPKEYQEYGE------------------KPDTRNQCWKPFSSHHSFRT-HEIIHTGEKLYDCKECGKTFFSLKRIRRHIITHSGYTPYKCKVCGKAFDYPSRFRTHERSHTGEKPYECQECGKAFTCITSVRR----------------------------HMIKHTGDGP--------------------------------------------------------YKCKVCGKPFHSLSSFQVHERIHTGEKPFKCKQCGKAFSCSPTLRIHERTHTGEKPYECKQCGKAFSYLPSLRLHERIHTGEKPFVCKQCGKAFRSASTFQIHERTHTGEKPYECKECGEAFSCIPSMRRHMIKHTGEGPYKCKVCGKPFHSLSPFRIHERTHTGEKPYVCKHCGKAFVSS----------------------------TSIRIHERTHTGEKPYECKQCGKAFSYLNSFRTHEMIHTGEKPFECKRCGKAFRSSSSFRLHERTHTGQKPYHCKECGKAYSCRASFQRHMLTHAEDGPPYKCMWESL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q96JL9-1", "uniprot_id": "ZN333_HUMAN", "id": "Q96JL9-1", "name": "Zinc finger protein 333", "aln": "MESVTFEDVAVEFIQ-EWALLDSARRSLCKYRMLDQCRTLASRGTPPCKPSCVSQLGQRAEPKATERGILRATGVAWESQLKPEELPSMQDLLEEASSRDMQMGPGLFLRMQLVPSIEERETPLTREDRPALQEPPWSLGCTGLKAAMQIQRVVIPVPTLGHRNPWVARDSAVPARDPAWLQEDKVEEEAMAPGLPTACSQEPVTFADVAVVFTPEEWVFLDSTQRSLYRDVMLENYRNLASVADQLCKPNALSYLEERGEQWTTDRGVLSDTCAEPQCQPQEAIPSQDTFTEILSIDVKGEQPQPGEKLYKYNELEKPFNSIEPLFQYQRIHAGEASCECQEIRNSFFQSAHLIVPEKIRSGDKSYACNKCEKSFRYSSDLIR----------------------------HEKTHTAEKC--------------------------------------------------------FDCQECGQAFKYSSNLRRHMRTHTGEKPFECSQCGKTFTRNFNLILHQRNHTGEKPYECKDCGKAFNQPSSLRSHVRTHTGEKPFECSQCGKAFREHSSLKTHLRTHTREKPYECNQCGKPFRTSTHLNVHKRIHTGEKLYECATCGQVLSRLSTLKSHMRTHTGEKPYVCQECGRAFSEP----------------------------SSLRKHARTHSGKKPYACQECGRAFGQSSHLIVHVRTHSAGRPYQCNQCEKAFRHSSSLTVHKRTHVGRETIRNGSLPLSMSHPYCGPLAN-----------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ::::** *:* : ** **:.:::.* : : : *.*: : * *:.: *::: . * . . * ... : :* : . . . . * : : :.*:* *. :. *.* : : *:* . :*: ::: .:: .: ::*:*.* *::* *:* : . * .**.: :.*: **: * * : * * ******::*.**.*:* .* :*:*.*********: ***** *: * * ******: * :*.*:* . :: * :**: ** ***::**:.* :. * ***: *:* *.: : * :: * :******** *:.**::* .:: * ***:*:*** *::**:**. : * *:. :*::*.:* *:* * : :*.* * * .. . ", "identical_positions": 141, "similar_positions": 140, "identity": "17.74%" }, { "cls_id": "homologset.agr.MGI:1261428", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0R785-1", "uniprot_id": "M0R785_RAT", "id": "M0R785-1", "name": "", "aln": "MPR-DSRSR-----TSRVTPPASRAP-------QMRAAPRRAPAAQPPATAAAPSAVGSPAAAPRQPGLMAQMATTAAGVAVGSAVGHTLGHAITGGFSGGANAEPAR--PDITYQEPQGAPLQNQHS----FGPCSLEIKQFLECAQ-NQSDVKLCEGFNEVLRQCRIANGLI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D1L0-1", "uniprot_id": "CHCH2_MOUSE", "id": "Q9D1L0-1", "name": "Coiled-coil-helix-coiled-coil-helix domain-containing protein 2", "aln": "MPR-GSRSR-----TSRVTPPASRAP-------QMRAAPRRAPAAQPPA-AAAPSAVGSPAAAPRQPGLMAQMATTAAGVAVGSAVGHTLGHAITGGFSGGGSAEPAK--PDITYQEPQGAQLQNQQS----FGPCSLEIKQFLECAQ-NQSDVKLCEGFNEVLRQCRIANGLM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y6H1-1", "uniprot_id": "CHCH2_HUMAN", "id": "Q9Y6H1-1", "name": "Coiled-coil-helix-coiled-coil-helix domain-containing protein 2", "aln": "MPR-GSRSR-----TSRMAPPASRAP-------QMRAAPRPAPVAQPPA-AAPPSAVGSSAAAPRQPGLMAQMATTAAGVAVGSAVGHTLGHAITGGFSGGSNAEPAR--PDITYQEPQGTQPAQQQ------QPCLYEIKQFLECAQ-NQGDIKLCEGFNEVLKQCRLANGLA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5T1J5-1", "uniprot_id": "CHCH9_HUMAN", "id": "Q5T1J5-1", "name": "Putative coiled-coil-helix-coiled-coil-helix domain-containing protein CHCHD2P9, mitochondrial", "aln": "MPR-GSRSR-----TSRMAPPASRAP-------QMRAAPRPAPVAQPPA-AAPPSAVGSSAAAPRQPGLMAQMATTAAGVAVGSAVGHTQGHAVTGGFSGGSNAEPAR--PDIAYQEPQGTQPAQQQ------QPCFYGIKQFLECAQ-NQGDIKLCEDFSKVLKQCRLAKGLA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VX77-1", "uniprot_id": "Q9VX77_DROME", "id": "Q9VX77-1", "name": "", "aln": "MVR-RGRSASPPPSTRRTAPVQARAPAPAPAPVQTRAPAPAASAPVPAPMSAPPSAVG--MPAPQQPSMFQQMAATAGGVAVGSAIGHTVGHGLTSLFSGSGDKEAAAPAPAAAAPAPQQPYYAQQQQPNEPQGACAWELKQFIQCAQ-GQADLTLCEGFNEALRQCKQSHHLQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q03667-1", "uniprot_id": "MIX17_YEAST", "id": "Q03667-1", "name": "Mitochondrial intermembrane space cysteine motif-containing protein MIX17", "aln": "MARSRGSSRP----ISRSRPTQTRSAS------TMAAPVHPQQQQQPNAYSHPP-AAG---AQTRQPGMFAQMASTAAGVAVGSTIGHTLGAGITGMFSGSGSDSAPVEQQQQNMANTSGQTQTDQQLG----RTCEIDARNFTRCLDENNGNFQICDYYLQQLKACQEAARQY", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * . * * * :*:. *. * . : .* *.* . .:**.:: ***:**.******::*** * .:*. ***... ... .. :*: .* ::* .* : .:.:. :*: : : *: *: : ", "identical_positions": 39, "similar_positions": 49, "identity": "22.41%" }, { "cls_id": "homologset.agr.MGI:1261433", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O08600-1", "uniprot_id": "NUCG_MOUSE", "id": "O08600-1", "name": "Endonuclease G, mitochondrial", "aln": "----MRALRAGLTLALGAGLGAAAEHWRRR---EGKAPGLLGRVP------LLPVVAA-DLPALP------------------------------------------------------------------GGPAGGTGELAKYGLPG-VAQLRSRE--SYVLSYDPRTRGALWVLEQLRPERLRG-DGDRSA--CDFREDDSVHAYHRATNADYRGSGFDRGHLAAAANHRWSQRAMDDTFYLSNVAPQVPH-LNQNAWNNLERYSRSLTRTYQNVYVCTGPLFLPR-TEADGKSYVKYQVIGKN-HVAVPTHFFKVLILEAAGG-----QIELRSYVMPNAPVDETIPLERFLVPIESIERASGLLFVPNILARAGNLKAITAGSK-------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14249-1", "uniprot_id": "NUCG_HUMAN", "id": "Q14249-1", "name": "Endonuclease G, mitochondrial", "aln": "----MRALRAGLTLASGAGLGAVVEGWRRRREDARAAPGLLGRLP------VLPVAAAAELPPVP------------------------------------------------------------------GGPRG-PGELAKYGLPG-LAQLKSRE--SYVLCYDPRTRGALWVVEQLRPERLRG-DGDRRE--CDFREDDSVHAYHRATNADYRGSGFDRGHLAAAANHRWSQKAMDDTFYLSNVAPQVPH-LNQNAWNNLEKYSRSLTRSYQNVYVCTGPLFLPR-TEADGKSYVKYQVIGKN-HVAVPTHFFKVLILEAAGG-----QIELRTYVMPNAPVDEAIPLERFLVPIESIERASGLLFVPNILARAGSLKAITAGSK-------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P08466-1", "uniprot_id": "NUC1_YEAST", "id": "P08466-1", "name": "Mitochondrial nuclease", "aln": "-----MCSRILLSGLVGLGAGTGLTYLLLN----KHSPTQIIETP------YPPTQKP-NSNIQS------------------------------------------------------------------HSFNVDPSGFFKYGFPGPIHDLQNRE--EFISCYNRQTQNPYWVLEHITPESLAARNADRKN--SFFKEDEVIPEKFRGKLRDYFRSGYDRGHQAPAADAKFSQQAMDDTFYLSNMCPQVGEGFNRDYWAHLEYFCRGLTKKYKSVRIVTGPLYLPKKDPIDNKFRVNYEVIGNPPSIAVPTHFFKLIVAEAPTANPAREDIAVAAFVLPNEPISNETKLTDFEVPIDALERSTGLELLQKVPPSKKKALCKEVNCQIVVRDFSNAAIKQSKDVKLLPPPKKRN----", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q8IPZ0-1", "uniprot_id": "Q8IPZ0_DROME", "id": "Q8IPZ0-1", "name": "Endonuclease", "aln": "MDRKWQLLGLGFVLGVTALCASFVGGMYFQHTDARKRLRELIQTDPYAYYLSPKIYEVFTFFESN------------------------------------------------------------------NEDDHRMRQIMKFGFPG-LDDLRLYS--DFVLSYDRRNRVAHWVCEHLQADSIHPNRGRRGR--NPYQPDLSVPSNFRSELSDYRRSGFDRGHLAAAGNHHLQQNHCEDTFFLTNIAPQVGQGFNRSAWNNLEQYVRNLVHRFGSVFVCTGPLYKPN-QRPGGKWAVEYEMIGLN-MVAVPTHFFKVIMVESKLHLG---KPYMEGYVLPNAPIPDGLPLRSFLCDIREIEHYAGLKFFDGLRRSALFGSNYPSESR-VFREFS------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VGU3-1", "uniprot_id": "Q9VGU3_DROME", "id": "Q9VGU3-1", "name": "", "aln": "-----MLTYVAIALCAVTGASCFILGALVQQHLSFRQIKSVMLTDPYVYQCRQPIYRALSMFGHSSRKSITRTESNQTASIGDESGTSKRYSERQDPGSVSIFEHFLLWGRRKAHNAISKMTLSVGPNGSRHENIEHVADIMKYGFPG-MDEIHVYK--NFVLSYDRRNRIAHWVCEHVKSGCVQERDEKTLNKPNAYITDNTIPTIFSANMRDFKNSDWVGGHLASPQNYKCDALKFLEAYKFTNIVP-INRGLKNHIWYRLESYVRDKAIEFDSVHVYTGPLFMPQRITFRN-WSVRYHVMGMN-TVAVPTHFFKIIIREDEFN---RDMPIMEGYVVPNAYVDKDMDLRSFLADVRDIEHFAGLKFCDGQQRDQLELPVKPPSMTDFQN---------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8IPY9-1", "uniprot_id": "Q8IPY9_DROME", "id": "Q8IPY9-1", "name": "", "aln": "----MEAPVKGIIGILATAGSFFALGAYYQHIDVMRKIRRLEQRNPHAYFIRRKLYALLGIFAVRPDNS---------------------------------------------------------EFDVDTDDCHKLGGIMKYGFPS-TNDITINETFDFVTSFDRRNSAILWMCERV----------------------------------DLSNRVVYGDSTSVAPAGAFGQSEAARVFFLSNIRPFLNRGFNLTVWDRLLQYVHEMSQRHGTVYAYTGSIYLPR-ELKSNSWFLEFQSEERT-MVAVPTHFFKILVIDKKFAG--DTIPYAEAYVMPNSPLNNNVELKTLLSDVREIENATGLRFFEGLDRNFVNTQASNSFVPSVNGPLTNPLTLPMTNALDSHSALTSSISPK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . : : *:*:*. :: . .:: .:: :. *: *:: * . : . .: ::*: * : . :: * .* : : . .* **.:: *. . :.:. :********::: : :*:** : . * : : :*. :** : ", "identical_positions": 29, "similar_positions": 63, "identity": "6.92%" }, { "cls_id": "homologset.agr.MGI:1261434", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9EQ09-1", "uniprot_id": "OLR1_MOUSE", "id": "Q9EQ09-1", "name": "Oxidized low-density lipoprotein receptor 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTFDD-KMKPANDEPDQKSCGKKPKGLHLLSSPWWFPAAMTLVILCLVLSVTLIVQWTQLR---------------------QVSDLLKQYQANLTQQDRILEGQMLAQQKAENTSQESKKELKGKIDTLTQKLNEKSKEQEEL-----------------------------------------------LQKNQNLQEALQRAANSSEESQRELKGKIDTITRKLDEKSKEQEELLQMIQNLQEALQRAANSSEESQRELKGKIDTLTLKLNEKSKEQEELLQKNQNLQEALQRAANFSGPCPQDWLWHKENCYLFH-GPFSWEKNRQTCQSLGGQLLQINGADDLTFILQAISHTT-----SPFWIGLHRKKPGQPWLWENGTPLNFQFFKTRGVSLQLYSSGNCAYLQDGAVFAENCILIAFSICQKKTNHLQI-----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O70156-1", "uniprot_id": "OLR1_RAT", "id": "O70156-1", "name": "Oxidized low-density lipoprotein receptor 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAFDD-KMKPVNGQPDQKSCGKKPKGLHLLSSTWWCPAAVTLAILCLVLSVTLIVQQTQLL---------------------QVSDLLKQYQANLTQQDHILEGQMSAQKKAENASQESKRELKEQIDTLTWKLNEKSKEQEKL-----------------------------------------------LQQNQNLQEALQRAVNASEESKWELKEQIDILNWKLNGISKEQKELLQQNQNLQEALQKAEKYSEESQRELKEQIDTLSWKLNEKSKEQEELLQQNQNLQEALQRAANSSGPCPQDWIWHKENCYLFH-GPFNWEKSRENCLSLDAQLLQISTTDDLNFVLQATSHST-----SPFWMGLHRKNPNHPWLWENGSPLSFQFFRTRGVSLQMYSSGTCAYIQGGVVFAENCILTAFSICQKKANLLLTQ----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P78380-1", "uniprot_id": "OLR1_HUMAN", "id": "P78380-1", "name": "Oxidized low-density lipoprotein receptor 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTFDDLKIQTVKDQPDEKSNGKKAKGLQFLYSPWWCLAAATLGVLCLGLVVTIMVLGMQLS---------------------QVSDLLTQEQANLTHQKKKLEGQISARQQAEEASQESENELKEMIETLARKLNEKSKEQ-------------------------------------------------------------------------------------------------------------------------------------------MELHHQNLNLQETLKRVANCSAPCPQDWIWHGENCYLFSSGSFNWEKSQEKCLSLDAKLLKINSTADLDFIQQAISYSS-----FPFWMGLSRRNPSYPWLWEDGSPLMPHLFRVRGAVSQTYPSGTCAYIQRGAVYAENCILAAFSICQKKANLRAQ-----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VPS1-1", "uniprot_id": "Q9VPS1_DROME", "id": "Q9VPS1-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MFKYDTYFLYLIVLLDPQ---GAQENNCPKVSLSERLEKRGEFSLVEFDPLLKFIVKN-------------------------PHKELLGEIEGLVGHTENKLQPMKSVIPNQSKALLN-YLDLHSKLEYLDAALQKAIN---------------------------------------------------------------------------------------------------------------------------------------------------SLQCSLKNTKVMSTGKPHPEFQKLGSRYFYIERHVRQNWFDAADKCRRMGGHLATPQDEDELYLIRKQLEAR-------WFWLDISNLVDKDQYIS-LATGKEVSYLKWRHGEPKKSSTANCAYLYAGDYYTYQCSDRNFFICQAV-----------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VLM0-1", "uniprot_id": "Q9VLM0_DROME", "id": "Q9VLM0-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MYKYATCIFSIFALWNFWGVSAKKQD------------TSTGTNELPKAPMPYYTIEN-----------------------------IDMHQQHWFTYNSLRQNGTLWRIGNMEQRLEMRLQSFQNQMETKLRALKQQIEP-------------------------------------------------------------------------------------------------------------------------------------------------------YMENVKMSNKIKMSVFKKIGSRHFYLEKQKKMPWDSAYDTCRQMGGHLANILDEKELNEIFSEETKK-------KYWVDINSRANDGASWISTLSGRDVPFLKWKPN-LATNIHNHCVYINSNEMYFENCANDNYFACQAEQWA--------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "M9PFV8-1", "uniprot_id": "M9PFV8_DROME", "id": "M9PFV8-1", "name": "", "aln": "MCGSHKMWCCQVFILALFAHTIAVEFHGSAARAEINFEGPSPAHSQDTAAPTSRPKRRVYALCPPKFHRVGTDCYSLVDQRSSWLEAHFFCKDKNANLTEPGKHADRKLRLFLQKQDALSGENDPIWLGATYDHHNNRWQWSMSGRNLSTDSFSRTDSAYVQLISNSQPLDNNCAIYDPSLKYRWSARPCSDKLRFICQHKMPKVSGPNRYKIYNRWNATYPNEQANEVVLEILEPRENDRRYHRRVKAEDSDEEMIIPDRRRNNNRRNNHRNRQIKNQNQHPNDVNYQPAQQRQRNRPRTSTVAPTTTQSVSQSNDVLAPSPTPQQMTQYDRKLQRQRERERRRQLRRQERQKLAREQKRERQRRLKEERQRLQREEQQRRQRLHHDEPKPQVNPQVKPQVIDELRQRSGEDLDKNQTDEHEQKLRNEQEKKLREEQQKQRDEQEQKDREEQDRLKQEEEQARTHQKELKENQEQQLRELKAKQEREKQERDYQQQKREHELELLKQRQAEADRQHAADEEAEKLRLERIQKQRELEAQQRREREEQRRKQREEQEEQDRQNHAKRLAEEKRLHDLYAERIRLANTEREKQLAEAHEAKRLEELKLQEQLKKQEDERQEQIRREQEEEEKRLELERLEEARRFEEKELKRLHEENQRREEQKLQREREIALREAAEKKLAEEEEMLRKEVAEEERKVKQRLEDEMRQAEEARKAKEAEERAAEEAKAAEQKRRVEAAKKKADEEVKAKLEEKRREYVTRISALSPEDQKKFIEMRKRRKQLKEKKERDQRAKELKRIQQAMRLDDNE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . : : . : . . : .: .:: : *: : . . : . :. .: : : . : *: : : ", "identical_positions": 2, "similar_positions": 33, "identity": "0.25%" }, { "cls_id": "homologset.agr.MGI:1261436", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZAQ3-1", "uniprot_id": "D3ZAQ3_RAT", "id": "D3ZAQ3-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------MSTEAYAMAEPTGQG---------------------------------------------------------------PKNPRVSSVMVQLEMKPLWEEFNQLGTEMIVTKAGRRMFPTFQVKIVGMDTLADYALLMDFIPLDDKRYRYAFHSSAWLVAGKADPATPGRVHFHPDSPAKGAQWMRQIVSFDKLKLTNNLMDDNGHIILNSMHRYQPRFHVVFVDPRKDSARYAQEN--FKSFVFMETQFTAVTAYQNHRITQLKIASNPFAKGFRE-----------ADPDSWPATPRPLLSIPARSRSSLGPCLLKGSAEREKDTSGTSASR------PRTPTQTHHQLLPAPDVLLAPAT--------------------------------------------YRPLPYQNLYPGSPSHAGT------SRARLAPYPLPNISTAGNQEDPTFAAGL-----------------GLLPTSALCLVPNQDSK-------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q810F8-1", "uniprot_id": "TBX10_MOUSE", "id": "Q810F8-1", "name": "T-box transcription factor TBX10", "aln": "--------------------------------------MAVFLSAGLG---------------------------VLAPPETCPHPETSTSWESRLGTRFPSGSC---TMSTEAQAMAEPTGQG---------------------------------------------------------------PKNPRVSSVMVQLEMKPLWEEFNQLGTEMIVTKAGRRMFPTFQVKILGMDTLADYALLMDFIPLDDKRYRYAFHSSAWLVAGKADPATPGRVHFHPDSPAKGAQWMRQIVSFDKLKLTNNLMDDNGHIILNSMHRYQPRFHVVFVDPRKDSARYAQEN--FKSFVFTETQFTAVTAYQNHRITQLKIASNPFAKGFRE-----------ADPDSWPVTPRPLLSIPARSRSSLSPCLLKGSAEREKDTSKASASS------SRTPTQPHNQLLPAPDVLLAPAT--------------------------------------------YRPLPYQNLYPGSPSRAGP------PRARLAPYPLPNISTAGDQEDPTLAAGL-----------------GLLPTSALCLVSNQASQ-------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75333-1", "uniprot_id": "TBX10_HUMAN", "id": "O75333-1", "name": "T-box transcription factor TBX10", "aln": "--------------------------------------MAAFLSAGLG---------------------------ILAPSETYPLPTTSSGWEPRLGSPFPSGPC---TSSTGAQAVAEPTGQG---------------------------------------------------------------PKNPRVSRVTVQLEMKPLWEEFNQLGTEMIVTKAGRRMFPPFQVKILGMDSLADYALLMDFIPLDDKRYRYAFHSSAWLVAGKADPATPGRVHFHPDSPAKGAQWMRQIVSFDKLKLTNNLLDDNGHIILNSMHRYQPRFHVVFVDPRKDSERYAQEN--FKSFIFTETQFTAVTAYQNHRITQLKIASNPFAKGFRE-----------SDLDSWPVAPRPLLSVPARSHSSLSPCVLKGATDREKDPNKASAST------SKTPAWLHHQLLPPPEVLLAPAT--------------------------------------------YRPVTYQSLYSGAPSHLGI------PRTRPAPYPLPNIRADRDQGGLPLPAGL-----------------GLLSPTVVCLGPGQDSQ-------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W3F4-1", "uniprot_id": "Q9W3F4_DROME", "id": "Q9W3F4-1", "name": "", "aln": "MTHLMGPTECAGAMMTTTSMQFLDTSLTDYNCYGNDYWTSPYMTGGLSPMKQIEACIQTAGKDRSSYKPLEQIDAKLADIETHSTGSTGTANSNSSTSSISNPSCPDQSSSSSSSSVSLPTDYAGVHSEASMAPTAGGTAVTTTSAGGVSASTASKKFKGQHKKDNNSAENGTVKPNSHNISKGESEPVHPSLAQAIVVLETKALWDQFHAQGTEMIITKTGRRMFPTFQVRIGGLDPHATYICMMDFVPMDDKRYRYAFHNSCWVVAGKADPISPPRIHVHPDSPAVGSNWMKQIVSFDKLKLTNNQLDENGHIILNSMHRYQPRFHLVYLPPKNASLDENEHSSHFRTFIFPETSFTAVTAYQNQRVTQLKISSNPFAKGFRDDGTNDVTTGGGSSMSSMSHESQARMKQQQQQQQQQQQQLQQQQQQQQQLKERTAATSNFGLSCSELAIEQQQQQQQQQGVLQLPATPSSSSTSGNSPDLLGYQMEQQLQQQHQQQQQQQHQSQQQHLHQQHQANQQQSLLQQSQNHTQYGSYHHAYQAQVQSHPLTPHSSSSASPPATAAPGASAATAAVAGGAGAAGAGGATSATQVMSAANIYSSIGQPYAQEQSNFGAIYHHNAAAAAAAHYHHGHAHGHAHSHAHAHAHGPYASAYDKLKVSRHAAAAAYGMGATYPSFYGSAAHHQMMRPNSYIDLVPR", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: : ::: **. . * :* :: . * ** *.**::*: *****:**:******.***:* *:*. * * :***:*:**********.*.*:******* :* *:*.****** *::**:************* :*:*****************:*:: *:: * :.. *::*:* **.*********:*:*****:*********: :. .* . .:. :. :.:.. : : :::: . ::*: .. . ::* ** *** ::. *.* : .: ::: .:**. : . . ..* * ..: : .. *. ", "identical_positions": 146, "similar_positions": 105, "identity": "20.89%" }, { "cls_id": "homologset.agr.MGI:1261437", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q91VR2-1", "uniprot_id": "ATPG_MOUSE", "id": "Q91VR2-1", "name": "ATP synthase F(1) complex subunit gamma, mitochondrial", "aln": "-MFSRASVVGLSACAVQPQWIQ--------VRNMATLKDITRRLKSIKNIQKITKSMKMVAAAKYARAERELKPARVYGTGSLALYEKADIK-----APEDKK-KHLIIGVSSDRGLCGAIHSSVAKQMKNEVAALTAAGKEVMIVGVGEKIKGILYRTHSDQFLVSFKDVGRKPPTFGDASVIALELLN--SGYEFDEGSIIFNQFKSVISYKTEEKPIFSLNTIATAETMSIYD-DIDADVLQNYQEYNLANLIYYSLKESTTSEQSARMTAMDNASKNASDMIDKLTLTFNRTRQAVITKELIEIISGAAALD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P35435-1", "uniprot_id": "ATPG_RAT", "id": "P35435-1", "name": "ATP synthase F(1) complex subunit gamma, mitochondrial", "aln": "----------------------------------ATLKDITRRLKSIKNIQKITKSMKMVAAAKYARAERELKPARVYGTGSLALYEKAEIK-----GPEDKK-KHLIIGVSSDRGLCGAIHSSVAKQMKNDMAALTAAGKEVMIVGIGEKIKSILYRTHSDQFLVSFKDVGRKPPTFGDASVIALELLN--SGYEFDEGSIIFNQFKSVISYKTEEKPIFSFSTVVAAENMSIYD-DIDADVLQNYQEYNLANIIYYSLKESTTSEQSARMTAMDNASKNASDMIDKLTLTFNRTRQAVITKELIEIISGAAALD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P36542-1", "uniprot_id": "ATPG_HUMAN", "id": "P36542-1", "name": "ATP synthase F(1) complex subunit gamma, mitochondrial", "aln": "-MFSRAGVAGLSAWTLQPQWIQ--------VRNMATLKDITRRLKSIKNIQKITKSMKMVAAAKYARAERELKPARIYGLGSLALYEKADIK-----GPEDKK-KHLLIGVSSDRGLCGAIHSSIAKQMKSEVATLTAAGKEVMLVGIGDKIRGILYRTHSDQFLVAFKEVGRKPPTFGDASVIALELLN--SGYEFDEGSIIFNKFRSVISYKTEEKPIFSLNTVASADSMSIYD-DIDADVLQNYQEYNLANIIYYSLKESTTSEQSARMTAMDNASKNASEMIDKLTLTFNRTRQAVITKELIEIISGAAALD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1P526-1", "uniprot_id": "A0A8M1P526_DANRE", "id": "A0A8M1P526-1", "name": "ATP synthase subunit gamma", "aln": "-MFART-----SAAVFLPQCGQ--------VRNMATLKDITIRLKSIKNIQKITKSMKMVAAAKYSRAERSLKPARVYGTGALALYEKAEIK-----APEDKN-KHLIIGVSSDRGLCGAIHSSVAKAIKSEIGKLSGAGKEVMVVNIGDKLRALLYRTHGKHILLNCKEVGRKPPTFTDASIIATELLN--SGYEFDQGSIVYNRFRSVISYKTDEKPLYSMDTVASSENMGIYD-DIDADVLRNYQEFALVNIIYFGLKESTTSEQSARMTAMDSASKNASEMIDKLTLTFNRTRQAVITKELIEIISGAAALD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O01666-1", "uniprot_id": "ATPG_DROME", "id": "O01666-1", "name": "ATP synthase subunit gamma, mitochondrial", "aln": "MMMQRTQLLLPLAMEATMLAQQ--------QRGMATLKMISIRLKSVKNIQKITQSMKMVSAAKYARAERDLKAARPYGIGAQQFFEKTEIQ-----PDEKAEPKKLLIAVTSDRGLCGAVHTGVARLIRGELAQDEAN---TKVFCVGDKSRAILSRLYGKNILMVANEVGRLPPTFLDASKIANEVLQ--TGYDYTEGKIVYNRFKSVVSYQCSTLPIFSGSTVEKSEKLAVYD-SLDSDVVKSYLEFSLASLIFYTMKEGACSEQSSRMTAMDNASKNAGEMIDKLTLTFNRTRQAVITRELIEIISGAAALT", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38077-1", "uniprot_id": "ATPG_YEAST", "id": "P38077-1", "name": "ATP synthase subunit gamma, mitochondrial", "aln": "-MLSRIVSNNATRSVMCHQAQVGILYKTNPVRTYATLKEVEMRLKSIKNIEKITKTMKIVASTRLSKAEKAKISAKKMDEAEQLFYKNAETKNLDVEATETGAPKELIVAITSDKGLCGSIHSQLAKAVRRHLNDQPNAD----IVTIGDKIKMQLLRTHPNNIKLSINGIGKDAPTFQESALIADKLLSVMKAGTYPKISIFYNDPVSSLSFEPSEKPIFNAKTIEQSPSFGKFEIDTDANVPRDLFEYTLANQMLTAMAQGYAAEISARRNAMDNASKNAGDMINRYSILYNRTRQAVITNELVDIITGASSLG", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **** : ****:***:***::**:*:::: ::**: .*: . . :::::: : * *.*::.::**:****::*: :*: :: .: :. :*:* : * * : .:: : : :*: .*** ::: ** ::*. .. : : .*.:* * :*:: . *::. .*: : .:. :: . *::* :. *: *.. : : :. :* *:* .***.*****.:**:: :: :*********.**::**:**::* ", "identical_positions": 81, "similar_positions": 111, "identity": "25.63%" }, { "cls_id": "homologset.agr.MGI:1261758", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AIG5-1", "uniprot_id": "A0A8I6AIG5_RAT", "id": "A0A8I6AIG5-1", "name": "", "aln": "MAPQKHGGGGGGGSGPSAGSGGGGFGGSAAAVAAAVASGGKSGGGGCGGGGGYSASSS----SAAAAGAAVLPVKKPKMEHVQADHELFLQAFEKPTQIYRFLRTRNLIAPIFLHRTLTYMSHRNSRTNIKRKTFKVDDMLSKVEKMKGEQES-------HSLSAHLQLTFTGFFHKNDKPSQNSENEQNSVTLEVLLVKVCHKKRKDVSCPIRQVPTGKKQVPLNPDLNQTKPGNFPSLAVSSNEFEPSNSHMVKSYSLLFRVTRPGRREFNGMINGETNENIDVSEELPARRKRN---REDGE--KTFVAQMTVFDKNRRLQLLDGEYEVAMQEMEECPIS---KKRATWETILDGKR--LPPFETFSQGPTLQFTLRWTGETNDKSTAPVAKPLATRNSESLHQEN-KPGSVKPAQTIAVKETLTTEMQTRKEKDTSNETRQKLRIFYQFLYNNNTRQQTEARDDLHCPWCTLNCRKLYSLLKHLKLCHSRFIFNYVYHPKGARIDVSINECYDGSYAGNPQDIHRQPGFAFSR-NGPVKRTPITHILVCRPKRTKASMSEFLESEDGEVEQQRTYSSGHNRLYFHSDTCLPLRPQEMEVDSEDEKDPEWLREKTITQIEEFSDVNEGEKEVMKLWNLHVMKHGFIADNQMNHACMLFVENYGQKIIKKNLCRNFMLHLVSMHDFNLISIMSIDKAVTKLR-------------------------------------------------------------------------EMQQKLEKGESAAPANEDIAEEQNGTANGFSETNSKEKALETDGVSGVPKQSKKQKL----------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80U70-1", "uniprot_id": "SUZ12_MOUSE", "id": "Q80U70-1", "name": "Polycomb protein Suz12", "aln": "MAPQKHGGGGGGGSGPSAGSGGGGFGGSAAAVAAAAS-GGKSGGGGCGGGGSYSASSSSAAAAAAAAGAAVLPVKKPKMEHVQADHELFLQAFEKPTQIYRFLRTRNLIAPIFLHRTLTYMSHRNSRTSIKRKTFKVDDMLSKVEKMKGEQES-------HSLSAHLQLTFTGFFHKNDKPSQNSENEQNSVTLEVLLVKVCHKKRKDVSCPIRQVPTGKKQVPLNPDLNQTKPGNFPSLAVSSNEFEPSNSHMVKSYSLLFRVTRPGRREFNGMINGETNENIDVSEELPARRKRN---REDGE--KTFVAQMTVFDKNRRLQLLDGEYEVAMQEMEECPIS---KKRATWETILDGKR--LPPFETFSQGPTLQFTLRWTGETNDKSTAPVAKPLATRNSESLHQEN-KPGSVKPAQTIAVKETLTTELQTRKEKDNSNESRQKLRIFYQFLYNNNTRQQTEARDDLHCPWCTLNCRKLYSLLKHLKLCHSRFIFNYVYHPKGARIDVSINECYDGSYAGNPQDIHRQPGFAFSR-NGPVKRTPITHILVCRPKRTKASMSEFLESEDGEVEQQRTYSSGHNRLYFHSDTCLPLRPQEMEVDSEDEKDPEWLREKTITQIEEFSDVNEGEKEVMKLWNLHVMKHGFIADNQMNHACMLFVENYGQKIIKKNLCRNFMLHLVSMHDFNLISIMSIDKAVTKLR-------------------------------------------------------------------------EMQQKLEKGESATPSNEEIAEEQNGTANGFSETNSKEKALETDGVSGVPKQSKKQKL----------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15022-1", "uniprot_id": "SUZ12_HUMAN", "id": "Q15022-1", "name": "Polycomb protein SUZ12", "aln": "MAPQKHGGGGGGGSGPSAGSGGGGFGGSAAVAAATAS-GGKSGGGSCGGGGSYSASSSSS--AAAAAGAAVLPVKKPKMEHVQADHELFLQAFEKPTQIYRFLRTRNLIAPIFLHRTLTYMSHRNSRTNIKRKTFKVDDMLSKVEKMKGEQES-------HSLSAHLQLTFTGFFHKNDKPSPNSENEQNSVTLEVLLVKVCHKKRKDVSCPIRQVPTGKKQVPLNPDLNQTKPGNFPSLAVSSNEFEPSNSHMVKSYSLLFRVTRPGRREFNGMINGETNENIDVNEELPARRKRN---REDGE--KTFVAQMTVFDKNRRLQLLDGEYEVAMQEMEECPIS---KKRATWETILDGKR--LPPFETFSQGPTLQFTLRWTGETNDKSTAPIAKPLATRNSESLHQEN-KPGSVKPTQTIAVKESLTTDLQTRKEKDTPNENRQKLRIFYQFLYNNNTRQQTEARDDLHCPWCTLNCRKLYSLLKHLKLCHSRFIFNYVYHPKGARIDVSINECYDGSYAGNPQDIHRQPGFAFSR-NGPVKRTPITHILVCRPKRTKASMSEFLESEDGEVEQQRTYSSGHNRLYFHSDTCLPLRPQEMEVDSEDEKDPEWLREKTITQIEEFSDVNEGEKEVMKLWNLHVMKHGFIADNQMNHACMLFVENYGQKIIKKNLCRNFMLHLVSMHDFNLISIMSIDKAVTKLR-------------------------------------------------------------------------EMQQKLEKGESASPANEEITEEQNGTANGFSEINSKEKALETDSVSGVSKQSKKQKL----------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0R1D5-1", "uniprot_id": "SZ12B_DANRE", "id": "B0R1D5-1", "name": "Polycomb protein suz12-B", "aln": "MAPQKY---------------------SAQVMNSKAN-------------------------GAVYPSSGVSSLKKPKIEQLQADHELFLQAFEKPTQIYRFLRTRNLITPVLLHRTLTFMSHRNSRTNAKRKSFKVDDLLSSVEKMKGEPES-------PSLTSHLQLTFTGFFHKNVKPCQNSENEQNSVSLEVLLVKVCHKKRKDVSCPIKQVPTGKKQVPLNPDLSQTKPGAFPSLLVSSNEFEPSNSHMVKSYSLLFRVSHTGKRDPNGFISCEADENIDVKDEIPPRRKRNSSLRGDGETTETFVAQMTVFDKNRRLQLLDGEYEVSMQQIEDCPVS---KKRATWETILDGKR--LPPFETFSQGPTLQFTLRWTADPSDPSTAPVAKPLSTRNSDTSTTES-RISTLRPAP-VAVKESVSTSMQSRIEHS-PCEPRQKLRIFYQFLYNNNTRQQTEARDDLHCPWCTLNCRKLYSLLKHLKLSHSRFIFNYVPHPKGARIDVSINECYDGSYVGNPQDIHSQPGFAFSR-NGPVKRTAVTHILVCRPKRTKPSLSEFLESEDGEPEQQRTYVSGHNRLYFHSDSCMPLRPQEMEVDSEDERDPEWLQEKTTTQIEEFTDVNEGEKEVMKLWNLHVMKNGFIADNQMSQASMLFVEICGPHIIRRNLCRNFLLHLVNLHDFNLVTIATIDQAMARLK-------------------------------------------------------------------------EIEESFPELEAGQ-------ESLDATCNGHSLS---------LGFSLHGKCTKLES-----------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6DC03-1", "uniprot_id": "SZ12A_DANRE", "id": "Q6DC03-1", "name": "Polycomb protein suz12-A", "aln": "MAPQKHG------------SGGNGFYGNSASKAANGG-------------------------AHASSGVVMTSVKRLKMEQIQADHQLFLEAFEKPTQIYRFLRTRNLITPIFLHRSLTYMSHRNSRTNSKRKSFSLNDLLFKVEKSKVDPES-------HNLASNLQLTFTGFFHKTEKQLQNSENEENSVSVEVLLVKLCHKKRKDVTCPVKQVPTGKKQVPLNPDISPTKLGAFPTLVVPSHEFEPVNSNTVKSYSLLFRASRPWGREHNGMTTRDT----NVIEELSNRKKRYCSHQDDGE--TTFVAQMTVFDKNRRLQLLDGEYEVSMQEIEESPVG---KKRATWETILDEKW--VPPFETFSQGPTLQFTLRWTNDTADKATAPVAKPLATRNSESSTVDSSKTSNIKPPQAVAVNDSLGTDLPVRREQT-HIEPCQKLHVYYQFLYNNNTRQQTEARDDLHCPWCTLNCRKLYSLLKHLKLSHSRFIFNYVPHPKGARIDVSINECYDGSYVGNPQDILCQPGFAFSR-NGPVKRTPVTQILVCRPKRSKPSLSEFLEPEDGEQEQQRTYISGHNRLYFHSDSCTPLRPQEMEVDSEDERDPDWLREKTAMQIEEFTDVNEGEKEIMKLWNLLVMKHGFIADNQMNQACMSFVEQHGTIMVEKNLCRNALLHLINMHDFGLITTATIDKAMTHLR-------------------------------------------------------------------------DLTQQSIAQH---------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9NJG9-1", "uniprot_id": "SUZ12_DROME", "id": "Q9NJG9-1", "name": "Polycomb protein Su(z)12", "aln": "MAPAKKREKDSN----PDGSAANGIIGLTHGAPDASN---------------------------AGSTVPPTAEGQVKLNGHQQEQELFLQAFEKPTQIYRYLRNRHETNPIFLNRTLSYMKERMSRNNKKRISFQVNSMLESITQKSEAVSQNYLHVIYDSLHEKLPARLDNESGEDLLQEQLLCEAGESVSVETTLYKITRSKRKDSTLDFQELLSKCSQIVYNP---KDRVGEHATISIPLQTMRPMG-EQHTLYKLLFRIKVLSPSTCN-----------DENAETPPNKRSR-----PNE--KMFGSELILYEKSS-GFITEGEYEAMLQPLNSTSIKSFSPKKCTWETMPDSYIPLSLTYDVYQQSPMLKFHLTLSNEQLPEMISAPELQRYVQHLDAVAEMNYNNNNYNNNNNCSGLKNGSGGGNSTVCKT----TPEHIQIVYNFMYSNNTRQQTEYTQELNCPWCGLDCLRLYALLKHLKLCHARFNFTYQPAGSGARIDVTINDAYDGSYAGSPYDLAGPSGSSFARTCGPVRRTSVTSLMVCRPRRQKTCLDEFLELDEDEISNQRSYITGHNRLYHHTETCLPVHPKELDIDSEGESDPLWLRQKTIQMIDEFSDVNEGEKELMKLWNLHVMRHGFVGDCQLPIACEMFLDAKGTEIVRKNLYRNFILHMCSLFDYGLIAAETVYKTVQKLQGLLSKYAAGQELMQRQREEQLKYWLDVGMHKKQEDPKTLKSPQKPAPPADQASTSSASTSGSGSGSSSMQPPKRMPAHLKRGSAASSPGVQSKGTENGTNGSNSSSSNSKNVAKKSADQPLSTLANTRERRSEYGQKRNVSGSRLAATPASKRKLSSKDNTVLNKRQRYSDGSPGTGIGNGHGGGSGSGANRNKSNNHSLPATSNNASSSSSNSKRAIARRRSTSERTKASGSTGGGAGGVRTRLSVPAKYERR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32832-1", "uniprot_id": "RSC7_YEAST", "id": "P32832-1", "name": "Chromatin structure-remodeling complex subunit RSC7", "aln": "------------------------------------------------------------------------------------------------------------MSDSEGGLASEVEHEKRSRSTSNRPNYAIDTEDLDIDENDENEDD----------------------DYREEEANEGVNEEEISDEEEQINKSGRNKRRHVDE--EEDLSEDKGVTRSRNRSKFKKPVFPGIDDAEENLNPLK-VVNEEYVLPDDPEGETKITADG--------------DLLGGR-------------EFLVRTFTLTEKGNRKFMLATEPARIVGFRDS---------------------------YLFFQTHPNLYKFILNQTQKNDLIDRGVLPYSYRNRQIALVTARGVFKEFGAKIIRGGKHITDDYYASELRT-------KGNVIEGKLAGDPIDKSARALETMMYPASENGINPAKNQVEFFEHRPHGHMSNSNIIASGSKLSSTN-----WLYQHSAACSRFNSDLFYDR----------VKVLLVDQQGLRDAYTNILHIPES---TQSTTVLGWRRSKNDSPSDTSIVYETVIHDNDLNKPKTGLSEIPKEIYEDVVDEDVLR---------------AITEQQNFEKCNEYI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .: **.. :* .: :: .: : . .. : : * : * :.**:. .: : . : . : .. : . . :.* * * : : : : : : :*. : * : :. : * : : . :: : . . : : .: : .: :.:. : : * . . ::.:: . . .*:::. : * .. .. : * . ::: : : . ::*. :. * : * .* .: : .: : : *.: : * : . ::. * : . : : * . :: ", "identical_positions": 25, "similar_positions": 127, "identity": "2.61%" }, { "cls_id": "homologset.agr.MGI:1261760", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9W4R3-1", "uniprot_id": "Q9W4R3_DROME", "id": "Q9W4R3-1", "name": "", "aln": "------------------------------------------MPVSAKRLLRNFQFTS--------------------------------CDRNGKMLIHLLLIVS---------LLEAIGAFQ-----PEFVESISNVSVAVGRDATFTCHVRHLGGYRVG-----------WLKADTKAIQAIHENVITHNPRVTVSHLDQN---TWNLHIKAVSEEDRGGYMCQLN-TDPMKSQIGFLDVVIPPDFIS--EDTSSDVIVPEGSSVRLTCRARGYPEPIVTWRREDGN----EIVLKDNVGTKTLAPSFRGEVLKLSKISRNEMGSYLCIASNGVPPSVSKRISLSIHFHPVIQVPNQLVGAPLGTDVQIECHVEASPKSINYWIKDTGEMIVTSGK----YHVQESSQSMYETKMSMIVRKFQKDDVGSYRCIAKNSLGEVDSSIRLYEIPGPNRNKNPLNGGG------------KGGGAGGSLDADANDILKQKQQVKVTYQPEDEELQYGSVEDFEAEGGEGGGLTPLSPHVYYTSGNKPATHKPGNSGGNQHLHQQHHHHHHHNNNNNNQQHSGGPGGGPTGGDAGSLG--GEMGGITRKPPPYYGGNTEVRGPIDNNEMSSGSGDSRLCRGHHLPILLLPFARLILVRSWHCRHTFLMGLSQACLPGLLLSLL-------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "B7Z153-1", "uniprot_id": "B7Z153_DROME", "id": "B7Z153-1", "name": "", "aln": "-----------MMNLLVVKESGERIADISCSQEHTTKFSPKLSQVAKHRKLAQLEIASGSGLVGLGTGTGTG----------------SGCGPAIRWQLLLLLLLGNCIDLTVSNKISSVGAFE-----PDFVIPLENVTIAQGRDATFTCVVNNLGGHRVSGDGSSAPAKVAWIKADAKAILAIHEHVITNNDRLSVQHNDYN---TWTLNIRGVKMEDAGKYMCQVN-TDPMKMQTATLEVVIPPDIIN--EETSGDMMVPEGGSAKLVCRARGHPKPKITWRREDGR----EIIARNGSHQKTKAQSVEGEMLTLSKITRSEMGAYMCIASNGVPPTVSKRMKLQVHFHPLVQVPNQLVGAPVLTDVTLICNVEASPKAINYWQRENGEMIIAGDR----YALTEKENNMYAIEMILHIKRLQSSDFGGYKCISKNSIGDTEGTIRLYEMERPG--KKILR------------------------DDDLNEVSK-NEVVQKDTRSED-------------------GSRNLNGRLYKDR----APDQHPASGSDQLLGRGTMRLIGTFLLALLVLFTALAEAGPTTLSCRTKG--GRQ---KKAKETSWNGRRARDGREDGH-----AAEWRQCWER---------------SALSWRRSAPPELDYYSLIQL------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A8JNC7-1", "uniprot_id": "A8JNC7_DROME", "id": "A8JNC7-1", "name": "", "aln": "----------------------------------------MFILTVVKLLLIALNIFP--------------------------------SRFTNRRIMFLIYMTN---------LVTHVMMDE-----PRFAQPIPNVTVAVGRDANLPCVVEHLGGYKVA-----------WIHIDRQMILTIHRHVISRIPRYSITYTDN----TWLLHVNQAHQDDRGYYMCQVN-TNPMISQVGYLQVVVPPNILDI-ESTPSSVAVRENQNINMTCRADGFPAPKIIWRREDGE----EIAVE----KKKKVLVYDADVLPLTKVSRNEMGAYLCIATNGVPPSVSKRIILDVEFSPMIWVPNQLVGAPSGTDVTIDCHTEAHPKAIIYWVYNS-VMVLPSKK----YKTDYTEN-SYRAHMKLTIRNLQYGDFGNYRCISKNSLGETEGSIRVYEIPLPSTPSKQVT---------------------------HTTVESRENNIIPSSRNDT--------------------TKSLQTDVGYAM----KNDLYPGSASSSSSGGSSSAASSS----SSMQTSALPG-GVAGNSLSSMG--SKGS-LAIGKSTFYTERPPNEYAASS------------------------------VAGLLLHRALLFGSGIYLTLL-------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8IP70-1", "uniprot_id": "Q8IP70_DROME", "id": "Q8IP70-1", "name": "", "aln": "-------------------------MAMAGPHRLPRPHTRRRFRLQAEFNVRQLAITII-------------------------------ATAAVTMLMTATPTLAEIPSKGKHTRLDTQQTAQEDSDFPRFAEPIANVTVSVGRDALMACVVENLKGYKVA-----------WVRVDTQTILSIHHNVISQNSRISLTYNDHR---SWYLHIKEVEETDRGWYMCQVN-TDPMRSRKGYLQVVVPP-IIVE-GLTSNDMVVREGQNISLVCKARGYPEPYVMWRREDGE----EMLIG-----GEHVNVVDGELLHITKVSRLHMAAYLCVASNGVPPSISKRVHLRVQFPPMLSIPNQLEGAYLGQDVILECHTEAYPASINYWTTERGDMIISDTSRAGDKYETTSTVSGYTKYMKLKIRAVGPNDFGTYRCVAKNSLGETDGNIKLDEMPTPTTAIISEMSLLNRSYDGKRRHRNKFDSANALPDYGVEEWRDGAQGNNAGNNGDNNQTPVRNPPGAFHNSAGSLAQHNLLAKIMLGIKTQSFGIFKRLSSSLPLAAGQSFLWLSTLSLVSAPSRWRMSNVENRPNSPETVVNNDTAAECWETRSHCVSESNNNNNSRITQRPPMWARHLRIFHIAHTPCGASTQYQRLCERQWQWQRLWQWQCQWKWQHQWQWPMLICIVILAGCFVRWLPMLLHFIGRHIGTFSISATHRQHLMCTFWDNRGNKVVAKNTTPARPSTFEMLCSRMFSR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VMN6-1", "uniprot_id": "Q9VMN6_DROME", "id": "Q9VMN6-1", "name": "", "aln": "MKIKIFPLTADAATIAARRQRRRAAGKLQRKREMPEISSRLIVATATAAVVSIICLSLALPGCAAQESDDEGELHHLDQMHHQHQDFIIGESEEHDHIAHHLAEMQNKDELLEDIREDTVVNAIPEKDLPKFGELLQNVTVPVSREAVLQCVVDNLQTYKIA-----------WLRVDTQTILTIQNHVITKNHRMSITHAEKR---AWILRIRDVKESDKGWYMCQIN-TDPMKSQVGYLDVVVPPDILD--YPTSTDMVIREGSNVTLKCAATGSPTPTITWRREGGE----LIPLPN----GAEAVAYNGSFLTIAKVNRLNMGAYLCIASNGIPPTVSKRVMLIVHFPPMIWIQNQLVGAALTQNITLECQSEAYPKSINYWMKND-TIIVPGER-----FVPETFESGYKITMRLTIYEVDIQDFGAYRCVAKNSLGDTDGAIKLYHIPQTTTMTTMAPTVSIN-------------------TVPVVLVKYNKEQRYGSSQNSNTNPYNFNP-----------GNSQQNTKLQRGKSNSKGSDQSPSGLNNVFVGATSSLWNSQDHHSSSSSSSSASSRGRDHHQQQHHQQQQQNHGSDHGASYRSDGKSPHLTNHDAKSLTDDLDRMQDLKG---------------WASRLSPISPILGLSMILGVGYLGPWPG------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VLF0-1", "uniprot_id": "Q9VLF0_DROME", "id": "Q9VLF0-1", "name": "", "aln": "--MLPPSWHLIGALLVLAATAGDSTNKIILPQILNGGGGGGGVGTAQGKHPSGSKTVATGVVPNFGGAAGNG---------------AGGGGPVAGSGTGSTVVGSNGVIVAGGGANVPTSNLNIVVEEPEFTEYIENVTVPAGRNVKLGCSVKNLGSYKVA-----------WMHFEQSAILTVHNHVITRNPRISVTHDKHDRHRTWYLHINNVHEEDRGRYMCQIN-TVTAKTQFGYLNVVVPPNIDD--SLSSSDVIVREGANISLRCRASGSPRPIIKWKRDDNS----RIAIN----KNHIVNEWEGDTLEITRISRLDMGAYLCIASNGVPPTVSKRIKVSVDFPPMLLIPHQLVGAPEGFNVTIECFTEAHPTSLNYWTRGEGPIIHDSHK---YKVEATVGLPAYKTHMKLTIINVSSGDDGIYKCVAKNPRGETDGIIRLYVSYPPTTASSGIYS---------------------------------TDTHWGEN--------------------------GINNNYAYGGPDSTRSIYAQDKNTRYQSNLNEIGLSEQKSFLDKTQNPLLANGNANEADAESNGARGHNPSMAIAWLFVVIAT------------------------------------------LLLTIRSAVGSSHSLSLC-------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q13449-1", "uniprot_id": "LSAMP_HUMAN", "id": "Q13449-1", "name": "Limbic system-associated membrane protein", "aln": "----------------------------------------MVRRVQPDRKQLPLVLLR-----------------------------------LLCLLPTGLPVRS-----------------------VDFNRGTDNITVRQGDTAILRCVVEDKNSKVA--------------WLNRSGIIFAGHDKWSLDPRVELEKRHSL---EYSLRIQKVDVYDEGSYTCSVQTQHEPKTSQVYLIVQVPPKISN----ISSDVTVNEGSNVTLVCMANGRPEPVITWRHLTPTGREFEG---------------EEEYLEILGITREQSGKYECKAANEVSSADVKQVKVTVNYPPTITESKSNE-ATTGRQASLKCEASAVPAPDFEWYRDDTRINSANGL----------EIKSTEGQSSLTVTNVTEEHYGNYTCVAANKLGVTNASLVLFRP----------------------------------------------------------------------------------------------GSVRGINGSISLAVPLWLLAASLLCLLSKC---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q62813-1", "uniprot_id": "LSAMP_RAT", "id": "Q62813-1", "name": "Limbic system-associated membrane protein", "aln": "----------------------------------------MVGRVQPDRKQLPLVLLR-----------------------------------LLCLLPTGLPVRS-----------------------VDFNRGTDNITVRQGDTAILRCVVEDKNSKVA--------------WLNRSGIIFAGHDKWSLDPRVELEKRHAL---EYSLRIQKVDVYDEGSYTCSVQTQHEPKTSQVYLIVQVPPKISN----ISSDVTVNEGSNVTLVCMANGRPEPVITWRHLTPLGREFEG---------------EEEYLEILGITREQSGKYECKAANEVSSADVKQVKVTVNYPPTITESKSNE-ATTGRQASLKCEASAVPAPDFEWYRDDTRINSANGL----------EIKSTEGQSSLTVTNVTEEHYGNYTCVAANKLGVTNASLVLFRP----------------------------------------------------------------------------------------------GSVRGINGSISLAVPLWLLAASLFCLLSKC---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BLK3-1", "uniprot_id": "LSAMP_MOUSE", "id": "Q8BLK3-1", "name": "Limbic system-associated membrane protein", "aln": "----------------------------------------MVGRVQPDRKQLPLVLLR-----------------------------------LLCLLPTGLPVRS-----------------------VDFNRGTDNITVRQGDTAILRCVVEDKNSKVA--------------WLNRSGIIFAGHDKWSLDPRVELEKRHAL---EYSLRIQKVDVYDEGSYTCSVQTQHEPKTSQVYLIVQVPPKISN----ISSDVTVNEGSNVTLVCMANGRPEPVITWRHLTPLGREFEG---------------EEEYLEILGITREQSGKYECKAANEVSSADVKQVKVTVNYPPTITESKSNE-ATTGRQASLKCEASAVPAPDFEWYRDDTRINSANGL----------EIKSTEGQSSLTVTNVTEEHYGNYTCVAANKLGVTNASLVLFS-----------------------------------------------------------------------------------------------KYAKTEPDSMQVIEFLHIDLKSIRHPLKVNPIQK-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7PLL7-1", "uniprot_id": "Q7PLL7_DROME", "id": "Q7PLL7-1", "name": "", "aln": "--------------------------MLTKKTARIKMYNGTLACSIAFILIKAITITK---------------------------------CHAVAHIHGKGESEE---------------------IDPQFLAKLSNTTVPIGRDISFTCVVDNLGHYRVA-----------WIKSDSKAILGIHTHMVSLNPRLSVTHNGHN---TWKLHISRVQINDSGSYMCQVN-TDPMKSLSGYLDVVVPPDILNHPEHNPEDGVCQEGGSISLMCSVTGVPRPKVLWRREAGK----EIILRTDGRDKTGFKSVEGERLVLTNVQRSDMGGYNCIASNGIPPSVSKRFNVYVNFSPTVKAISQLVGAPVEREVTLECIVEVFPKPLNGWYRSEGNIKLHNGN---KYNISEEVINIYTWHLNLTIRHLTKSDFGTYSCSSVNALGKSESLIRLQELRLPPKLTTTPTP--------------------------HMQTTGKSRRKHPASHKKG---------------------LNEVLRFQETHFANQIQQENEDHNEGFDLLKFTNSENSNIVLESGHINSMINKEDVNIYHPKQYGQEKTNKPSGTIPSTRTPWILTNAGSQRPALTSYATVALITSFWLFFWRVFHSLDWDAIRVSSVVHHVVVFKRRSYFEAPNYALRITVLQMLQELRTLVIEQ---------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * :: . : * * . : . * . : * : : *.: . * * * *.:: * * :** : . . *. . : * . * * * : *:: . * : : * . . * * *:* :..: *:. : :.: * : . * : : * .. * . * : . : : . . * * * : * * :. : : ", "identical_positions": 38, "similar_positions": 62, "identity": "5.04%" }, { "cls_id": "homologset.agr.MGI:1261768", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5FVN1-1", "uniprot_id": "STBD1_RAT", "id": "Q5FVN1-1", "name": "Starch-binding domain-containing protein 1", "aln": "--------------------MGAVWSALLVG--GGLAGALILWLLRGDSGAPGKDGGAEP-LKDAPPGEAAAP-----------------------------GGGPGGGGSGGLSPEPSDREL------------------------------------VSKAEHLRESNGHLISESKDLG---NLTEA-QRLQNVG-------NAREYVPVGKVPDTHSRANSETS---------RNQSPESRVG-----------------------------EWRLPKGHETAVKVAGSVAEKLPSS-------------------------------------------------SPLMDRAEAAS------LAQSAGHEDWEVVSRHSSWGSVGLGGSLEASRLSLNQGMDESRNSLVGG-GWEVDGKVVSVK-----PRQVSIQFKVHYSTSTDVQFIAVTGDHESLGGWNTYIPLHYCKDGLWSHSVFLPADTVVEWKFVLVENKEVTRWEECSNRRLQTG--HEDKVVHGWWGIH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C7E7-1", "uniprot_id": "STBD1_MOUSE", "id": "Q8C7E7-1", "name": "Starch-binding domain-containing protein 1", "aln": "--------------------MGAVWSALLVG--GGLAGALILWLLRGDSGAPGKDGVAEPPQKGAPPGEAAAP-----------------------------GDGPGGGGSGGLSPEPSDREL------------------------------------VSKAEHLRESNGHLISESKDLG---NLPEA-QRLQNVGADWV---NAREFVPVGKIPDTHSRADSEAA---------RNQSPGSHGG-----------------------------EWRLPKGQETAVKVAGSVAAKLPSS-------------------------------------------------SLLVDRAKAVS------QDQ-AGHEDWEVVSRHSSWGSVGLGGSLEASRLSLNQRMDDSTNSLVGGRGWEVDGKVASLK-----PQQVSIQFQVHYTTNTDVQFIAVTGDHESLGRWNTYIPLHYCKDGLWSHSVFLPADTVVEWKFVLVENKEVTRWEECSNRFLQTG--HEDKVVHGWWGIH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95210-1", "uniprot_id": "STBD1_HUMAN", "id": "O95210-1", "name": "Starch-binding domain-containing protein 1", "aln": "--------------------MGAVWSALLVG--GGLAGALFVWLLRGGPGDTGKDGDAEQ-EKDAPLGGAAIP-----------------------------GGHQSG--SSGLSPGPSGQEL------------------------------------VTKPEHLQESNGHLISKTKDLG---KLQAASWRLQNPSREVCD--NSREHVPSGQFPDTEAPATSETSNSRSYSEVSRNESLESPMG-----------------------------EWGFQKGQEISAKAATCFAEKLPSS-------------------------------------------------NLLKNRAKEEMSLSDLNSQDRVDHEEWEMVPRHSSWGDVGVGGSLKAPVLNLNQGMDNGRSTLVEARGQQVHGKMERVAVMPAGSQQVSVRFQVHYVTSTDVQFIAVTGDHECLGRWNTYIPLHYNKDGFWSHSIFLPADTVVEWKFVLVENGGVTRWEECSNRFLETG--HEDKVVHAWWGIH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PYN9-1", "uniprot_id": "A0A8M1PYN9_DANRE", "id": "A0A8M1PYN9-1", "name": "Starch-binding domain-containing protein 1", "aln": "MKKSQPIALDGRDIQSLLDAVGGFGSVVAVGIIAMLSVCAAFFIYRSFRGQRGKTDEINGKETTVATGEESAVRRRRTEKDDRPTESTAECQDAKQKKHRSESSYSSATNNIPLPTEAAEKDLNESTLKDLEEITDELLTDLEPEMGDKTDSDFDPCMEIDPDENTECEEDHIRLKENDDGGCEVVADACVRLTQLDCQIEKTEEFLDKPEGGQSLDTDEPSETESAQDIVYQRRQDTLHNSSSCQSVDHKPSKNHLEEDIKTAEEACKKFEDHHDWRFARTNNFDCCCCDKKMERMKGQPWFPIGSYATDTFTPTVETMVNHCSRFDFQNYLGFQTDNTFIGVSSTQMSLSQEKKANEEGATVEVKHEKNQISIMDAIMDNNEWLNVGAPEFKDRPWLTPNASINEEGKPKADLAKDEEELANKRVATVPPLAQTVSVTFRIHYITHSALQLVAVTGSLQELGAWESFIPLQRAKDGFWANTVSLPVESQVEWKFVLVEDGRISRWEECGNRYLCLTSQDEEVFLEKCWGCC", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*.. *.: ** . *: . .:: *. * ** . : . .. * : .. .. . *.. .: ::* : *: . .:.*: : :* * : * ** : . : : *: **. : :*:: . * :* : : :: . :: .. . :: : . : : :..* .** . . *. * ::: .. . : . : .: **: *::** * : :*::****. : ** *:::***: ***:*:::: **.:: *********: ::*****.** * .*: .:. ** ", "identical_positions": 73, "similar_positions": 115, "identity": "13.7%" }, { "cls_id": "homologset.agr.MGI:1261771", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0M380-1", "uniprot_id": "A0ABK0M380_RAT", "id": "A0ABK0M380-1", "name": "RING finger protein 24", "aln": "--------MSSDFPHYNFRMPNIGFQNLPLNIYIVVFGTAVFVFILSLLFCCYLIRLRHQAHKEFYAYKQVILKEKVKELNLHELCAVCLEDFKPRDELGICPCKHAFHRKCLVKWLEVRKVCPLCNMPVLQLAQLHSKQD-RGPPQEPLPGAENIV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BGI1-1", "uniprot_id": "RNF24_MOUSE", "id": "Q8BGI1-1", "name": "RING finger protein 24", "aln": "--------MSSDFPHYNFRMPNIGFQNLPLNIYIVVFGTAVFVFILSLLFCCYLIRLRHQAHKEFYAYKQVILKEKVKELNLHELCAVCLEDFKPRDELGICPCKHAFHRKCLVKWLEVRKVCPLCNMPVLQLAQLHSKQD-RGPPQEPLPGAENIV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y225-1", "uniprot_id": "RNF24_HUMAN", "id": "Q9Y225-1", "name": "RING finger protein 24", "aln": "--------MSSDFPHYNFRMPNIGFQNLPLNIYIVVFGTAIFVFILSLLFCCYLIRLRHQAHKEFYAYKQVILKEKVKELNLHELCAVCLEDFKPRDELGICPCKHAFHRKCLIKWLEVRKVCPLCNMPVLQLAQLHSKQD-RGPPQGPLPGAENIV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B6Y0-1", "uniprot_id": "A0A8M2B6Y0_DANRE", "id": "A0A8M2B6Y0-1", "name": "RING finger protein 24", "aln": "MIYLPVLSMTSDLQHYSFRMPNIGFQNLPLNIYIVVFGTAIFVFILSLLFCCYLIRLRHQAHKELYAYKQVIQKEKVKELNLHEICAVCLEEFKQKDELGICPCKHAFHRKCLIKWLEVRKVCPLCNMPVLQLAQQQSMSEPIAPTQQHLPGVENLV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:**: **.***********************:***********************:******* ***********:******:** :*****************:********************* :* .: .*.* ***.**:*", "identical_positions": 124, "similar_positions": 16, "identity": "78.98%" }, { "cls_id": "homologset.agr.MGI:1261775", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A4K3-1", "uniprot_id": "BAKOR_RAT", "id": "D4A4K3-1", "name": "Beclin 1-associated autophagy-related key regulator", "aln": "--MASPSGKGSWTP------EAPGFGP--RALAPD------------------LVDSVDDAEGLYVAVERCPLCN-TTRRRLTCAKCVQSGDFVYFDGRDRERFIDKKERLSQLKNKQEEFQKEVLKAMEGKRLTDQLRWKIMSCKMRIEQLKQTICKGNEEMKKNSEGLLKNKEKNQKLYSRAQRHQEKKEKIQRHNRKLGDLVEKKTSDLREHYDRLACLRRLHILELTSVIFPMDEVKTSGRDPAD-VSSETDSAMTSSMVSKLAEARRTTYLSGRWVCDDHNGDTSISITGPWISLPNNGDYSAYYNWVEE-KKTTQGPDMEHNNP----AYTISAALGYATQLVNIVSHILDINLPKKLCNSEFCGENLSKQRLTRAVRKLNANILYLCSSQHVNLDQLQPLHTLRNLMHLVSPHSEHLGRSGPFEVRADLEESMEFVDPGVAGESDVSGDERVSDEETDLGTDWENLPSPRFCDIPSQPVEVSQSQSTQASPPIASSSAGGMISSAAASVTSWFKAYTGHR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CDJ3-1", "uniprot_id": "BAKOR_MOUSE", "id": "Q8CDJ3-1", "name": "Beclin 1-associated autophagy-related key regulator", "aln": "--MASPSGKGSWTP------EAPGFGP--RALARD------------------LVDSVDDAEGLYVAVERCPLCN-TTRRRLTCAKCVQSGDFVYFDGRDRERFIDKKERLSQLKNKQEEFQKEVLKAMEGKRLTDQLRWKIMSCKMRIEQLKQTICKGNEEMKKNSEGLLKNKEKNQKLYSRAQRHQEKKEKIQRHNRKLGDLVEKKTIDLKSHYERLARLRRSHILELTSIIFPIDEVKTSGRDPAD-VSSETDSAMTSSMVSKLAEARRTTYLSGRWVCDDHNGDTSISITGPWISLPNNGDYSAYYNWVEE-KKTTQGPDMEHNNP----AYTISAALGYATQLVNIVSHILDINLPKKLCNSEFCGENLSKQKLTRAVRKLNANILYLCSSQHVNLDQLQPLHTLRNLMHLVSPRSEHLGRSGPFEVRADLEESMEFVDPGVAGESDASGDERVSDEETDLGTDWENLPSPRFCDIPSQPVEVSQSQSTQVSPPIASSSAGGMISSAAASVTSWFKAYTGHR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZNE5-1", "uniprot_id": "BAKOR_HUMAN", "id": "Q6ZNE5-1", "name": "Beclin 1-associated autophagy-related key regulator", "aln": "--MASPSGKGARAL------EAPGCGP--RPLARD------------------LVDSVDDAEGLYVAVERCPLCN-TTRRRLTCAKCVQSGDFVYFDGRDRERFIDKKERLSRLKSKQEEFQKEVLKAMEGKWITDQLRWKIMSCKMRIEQLKQTICKGNEEMEKNSEGLLKTKEKNQKLYSRAQRHQEKKEKIQRHNRKLGDLVEKKTIDLRSHYERLANLRRSHILELTSVIFPIEEVKTGVRDPAD-VSSESDSAMTSSTVSKLAEARRTTYLSGRWVCDDHNGDTSISITGPWISLPNNGDYSAYYSWVEE-KKTTQGPDMEQSNP----AYTISAALCYATQLVNILSHILDVNLPKKLCNSEFCGENLSKQKFTRAVKKLNANILYLCFSQHVNLDQLQPLHTLRNLMYLVSPSSEHLGRSGPFEVRADLEESMEFVDPGVAGESDESGDERVSDEETDLGTDWENLPSPRFCDIPSQSVEVSQSQSTQASPPIASSSAGGMISSAAASVTSWFKAYTGHR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1R340-1", "uniprot_id": "F1R340_DANRE", "id": "F1R340-1", "name": "", "aln": "--MACPSTGEPLALGPNVSEEHPESGSEARAPARSQPPHQHLQPACMSAGAAVMVEALDDAEGLFVAVERCPLCN-TARRRLTCARCIQNGDFVYFDGRNPERYSEKLERLQKLKNEKEDLQQRVIKAMDKKVQADQLRWKIMSCKMKIQQLKEAICTSNEEVKSGKELLLRSQEEGQRLQRRASRHQEKRDKIKRHNQRLGELLEKRSKEMQGRLEALAEVRREHILELTTHIFNIQEEKQGSRDPADPAVAEYDLALTSSTVSELAEARRTTYHSGRWIWDDQNGETSISITGPHVTLPSNGDCSAYYSWVEE-KSGNQGPELDYINP----AHTISAALCYATQLVNILSHILDVNLPKKLCNSEFCGDNLTRYRFTRTVNKLNTNVLHLCFSQHVDGELLHPHHTLRNIMFLVSPVNKNLGRTGPFEVSADLEESMEFVEPEAAGPAEESGDEAVTDEETDLGTDWETVPSPRFCDIPSQPMDLSQS-GMQASQPVG-NAGGGMISSAAASVTSWFRAYTGQR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VAP6-1", "uniprot_id": "Q9VAP6_DROME", "id": "Q9VAP6-1", "name": "", "aln": "MANSSSSDESCKAPDNFRISSASTNGEDEESDVAGYTTKRRPTAATKELLKDANAKDRNATTGMGAHMR-CPLCHSCSASRFHCRNCVRNGNITHSQAERPESLTEKQQRYINLQAGLKTFSTRYERLIGQHRSNEDRLMAIKAKRKQLELLQQLISGTGQRLRVLGERRDELRRANAEKRKNLPKYPDKVKMLENYVLDRVEKIEKLRETHLGLLDSIKQAARRSIQQLVTYVFPIAEVVLKEEQQRR---ASVERTEEAETIAALADAKNTSYIRGKWVFHG-SGISEVQYRIVGPSLPANGDYTAYLDWLADNKDDVPKATANEITPSRFEAYRIVGALTYTAQLTQLLSFYLNVRLPHKIAYGDFCRKLLNEEQFRRKISRLNSNIMYLAYTQQVKLRALIEQHTLENLLAILDLERSDLGRYGHLDVNN--APLMKSVDSLLIG--IETATESESEDENSLRMDWEAVPS-----LTPQPELADPN----LMPAANQQSTIAFVRMAATSVLRWIK------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :..* : . . * .. . . .. : : *: . :. ****: : *: * .*::.*::.: :.. * :* :* .*: : :. . : : : :: * : : ::: *:: *. .:.:. * . :. . . . :: :* . ::.: : :** : : * * :*.: :* : * .: :. : : :. :: **:*:.*:* *:*: .. .* :.:. :** *** :** .*: : *. . : .* *: * .** *::**.:::*. *::.**:*:. .:** . *.. :: * : :**:*:::*. :*:*. * ***.*:: ::. ..*** * ::* *: *:. * :. * :::*..* *** :** :..*. . . . .: .:: **:** *:: ", "identical_positions": 94, "similar_positions": 181, "identity": "17.84%" }, { "cls_id": "homologset.agr.MGI:1261780", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8M1RTG9-1", "uniprot_id": "A0A8M1RTG9_DANRE", "id": "A0A8M1RTG9-1", "name": "", "aln": "-----------------------MAIIIISLLLLVSLVPDLTFTARV-----GIEDGTEAKPHSRPYMVSLQK----NSWHTCGGFLITEQFVLTAAHCWKK--GDVITVVVGAHDLSGNEIYDT---------FKVTSYMRYEDYKLNSDRNDIMLLKLNKKVRLSKNVGLISLPKK---GEDVEADTLCSVAGWGILWRKGPESDRLREAETVIVNNAECERRWES------LYKASKMICAYGHG---GTCNGDSGGPLVCGNTAVGITSFGDR----YLCNSRLLPDVYTRISAYLPWIHNITGNA------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1RP83-1", "uniprot_id": "A0A8M1RP83_DANRE", "id": "A0A8M1RP83-1", "name": "trypsin", "aln": "-----------------------MTIIIISLLLLVSLVPDLTYTAHV-----GIEDGTKAKPHSRPYMVSLQK----NSRHSCGGFLITEQFVLTAAHCWKK--GDVITVGVGAHDLSGNEIYDT---------FEVTSYIPHPEYKLNSDRNDIMLLKLNKKVRLSYNVGLISLPKD---GEDVEADILCSVAGWGRLWLKGPSPDRLREAETVIVNDAECERRWNK------TYKASKMICAYGHG---GSCSGDSGGPLVCNNTAVGITSFSDR----YLCNSRLLPNVYTRISAYLPWIHNITGNVYKKK--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32TKN4-1", "uniprot_id": "A0AB32TKN4_DANRE", "id": "A0AB32TKN4-1", "name": "trypsin", "aln": "-----------------------MTIIIISLLLLVSLVPDLTFTARV-----GIEDGTEAKPHSRPYMVSLQK----NSKNSCGGSLITEEFVLTAAHCWKK--GDVITVVVGAHDLSENETYDS---------FEVTSYIPHPEFSWQNYENDIMLLKLNKKVTLSDNVGLISLPKN---GEDVKEDAVCSVAGWGRLWLNGPRPDRLMEAETVIVSGEECKRRWES------LFKPSKMFCVYGHG---GTCKGDSGGPLVCGDHAVGVTSFSDR----YSCNSRLLPNMYTKISAYLSWIQKITGKI------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9PSZ8-1", "uniprot_id": "A0A8M9PSZ8_DANRE", "id": "A0A8M9PSZ8-1", "name": "", "aln": "-----------------------MTITIISLLLLVSLVPDVTFTARV-----GIVDGTEAKPHSRPYMVSLQY----DGEHICGGSLITEEFVLTAAHCWEE--GDVLTVVVGAHDLSKNEIYNS---------YEVASYIPHQDYELNPDLNDIMLLKLKKKVRLSNSIGLISLPKD---GEDVEADTICSVAGWGDLWSKGPVPDRLMEAETVIVNDAECERRWGS------EYVASEMICAYGHG---GSCNGDSGGPLVCNNTAVGITAFGDG----YLCNSRLYPNAYTKISAYLQWIRFKLENV------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9Q575-1", "uniprot_id": "A0A8M9Q575_DANRE", "id": "A0A8M9Q575-1", "name": "", "aln": "MSPPNFSVFIQCLYSESSLIFFIMTIITISLLLLVSLVPHLTFTARV-----GIVDGTEAEPHSRPYMVSLQK----KSRHICGGFLIHQQFVLTAAHCWK---GDPLTVVVGAHDLRMTDSSNS---------FKVTSYVQHPNFDSNTFENDIMLLKLNKKVTLSNNVGLISLPKY---GEDVKADTACSVAGWGRLSKKGPKPDRLREAETVIVNDAECERRWGQ------TYVASEMICVYGPG---GTCKGDSGGPLVCGDTAVGITSFSDP----YLCNSRVYPSIFTRISAYLSWIYHLTENV------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9Q7D5-1", "uniprot_id": "A0A8M9Q7D5_DANRE", "id": "A0A8M9Q7D5-1", "name": "", "aln": "-------------------------MTIISLLLLVSLVPHLTFTARV-----GIQDGTEAKPHSRPYMVSLQF----YKLHMCGGSLITEEFVLTAAHCWEE--DDVLTVVTGAHDLRKKAINNV---------YKVKSYIPHPDFNSKTLENDIMLLQLKTKVRLSNNVGLISLPKD---GEDVKADTLCSVAGWGDLWSKGPETDRLREAETVIVNNAECERRWES------DYVASKMICVYGHG---GTCSGDSGGPLVCGDTVVGITSFGEP----YLCNSRLFPDVHTRISAYLPWIHNITGKV------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB13A940-1", "uniprot_id": "A0AB13A940_DANRE", "id": "A0AB13A940-1", "name": "", "aln": "-----------------------MTIIIISLLLLVSLPPHLTFT----------VNGNEATPHSRPYMVSVQF----NDIHFCGGFLISEEFALTAAHCRKNS-AEKLTVVVGAHDLKNKEEGSVR--------IKVKSCYTHPHFVQKTLQNDIMLLKLERNVKLSQTVHLTSLPKQ---KEDTKAGTICSVFGWGRQYTNGPLSDRLLETEVKIMENMQCLKLWNKRDDIKVKYSISKMMCVYGHG---GSCEGDSGGPLVCEDTVVGITSFGNP----HLCNSRLFPNVYTKISAYHDWIWKIINKQK-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M6YV09-1", "uniprot_id": "A0A8M6YV09_DANRE", "id": "A0A8M6YV09-1", "name": "trypsin", "aln": "-----------------------MTLITFFLLLLVSLLPHLTFMAHV-----GIVNGSVAKPHSRPYMVSVQL----DGQHICGGFLITEEFVLTAAHCWNG--EENLTVVVGAHDLRQSMASDR---------IEVESYIRHPSYNSKFIWNDIMVFKLKERVTQNSSVGWISISKK---NEHVDANTLCSVAGWG-LLTNGTLSDCLMEANVYIISNTECKSKWGR------HFSVSQMMCTRGHG---GSCRYDSGGPLVCGDTAVGITSFGDP----HLCNSPKHPNVYTNISAYRPWIDSVIKNGKLDNIFNYYRAF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1PUX6-1", "uniprot_id": "A0A8M1PUX6_DANRE", "id": "A0A8M1PUX6-1", "name": "trypsin", "aln": "----------------------MQYIMLLCVFLLLSLFS-LSGGLES-----GIVGGREAKHHSRPYMASLQK----KRNHVCGGMLIKEDYVLTSAHCWNETDKYSLQIVLGAHNISQKENSQQI--------IQVEKYIKHRKF-------DIMLLKLRTKAVLNHFVDIINLPKH---EISILAPLECSIAGWGMKRPGEGASNVLRVVNLQLESNAKCKSKWQT------HFNFKNMVCTVSDGK-KAFCQGDSGSPLLCNSELYGMAAYTYP----KNCTFKEYPEVYMKVSAFLPWIKKNIQ--------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q06606-1", "uniprot_id": "GRZ2_RAT", "id": "Q06606-1", "name": "Granzyme-like protein 2", "aln": "--------------------------MFLFLIFLVAVLPVNTEGGE-------IVWGTESKPHSRPYMASLMFYYGNSYRHYCGGFLVAKDIVMTAAHCNES----NIKVILGAHNIKKRENTQV---------FSVVKAKPHENYDSHSLFNDIMLLKLERKAQLNGVVKTIALPRS---QDWVKPGQVCTVAGWG-RLANCTLSNTLQEVNLEVQKGQKCQGMSED-------YNDSIQLCVGNPSEGKATGKGDSGGPFVCDGVAQGIVSR-------RLCTG-TLPRVFTRISTFIPWIQKTMKLLQQP---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97594-1", "uniprot_id": "MCPT8_RAT", "id": "P97594-1", "name": "Mast cell protease 8", "aln": "--------------------------MFLFLFFLVAILPVNTEGGE-------IIWGTESKPHSRPYMAFIKFYDSNSEPHHCGGFLVAKDIVMTAAHCNGR----NIKVTLGAHNIKKQENTQV---------ISVVKAKPHENYDRDSHFNDIMLLKLERKAQLNGVVKTIALPRS---QDWVKPGQVCTVAGWG-RLANCTSSNTLQEVNLEVQKGQKCQDMSED-------YNDSIQLCVGNPSEGKATGKGDSGGPFVCDGVAQGIVSY-------RLCTG-TLPRVFTRISSFIPWIQKTMKVLQQS---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P43430-1", "uniprot_id": "MCPT8_MOUSE", "id": "P43430-1", "name": "Mast cell protease 8", "aln": "--------------------------MFLLLVLLVAALPVNAEGGE-------IIWGTESKPHSRPYMAYIRFNDSKS-VYRCGGFLVARDIVMTAAHCNGK----VINVTLGIHNLKKKKNTQL---------IPVSEAIPHESFDNETLVNDIMLLKLERKAQLNSAVDTIALPKS---KDWVKPGQVCTVAGWG-KLANCTLSDTLQEVNLEVQKGQKCRSMSQT-------YNDSIQLCVGNPSENKATGKGDSGGPFVCNGVVQGIVSC-------RLCTG-TLPRVFTRISSFMPWIRKTMKLLQQP---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A1ZAG8-1", "uniprot_id": "A1ZAG8_DROME", "id": "A1ZAG8-1", "name": "Peptidase S1 domain-containing protein", "aln": "----------------MKLIPALLALLILGHGISLGYSYLLEWDCGISKYTYRITGGRDSPLMLNPWLAYLHIN----SKFICGGSLLNHWFVLTAAHCFRDK-NAKVLVRLGENDASQKIDCNESECAAPHLEYMIMQKLIHPLYR-TAHYYDIALAKLNRYVVYTDSIRPICLMLNPNWQVYVDTIRYFIITGWG-ATNASEVSDKLQLTRIPQIDRFTCRYWFGY-------MVDRTHICAGESK--HYVGKGDSGGPLGSMVDYKYAKRFFQFGIVSHLRQPFHGVSVFTNILSYSNWIHRTIITNSGH---------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :. * : .*::. : *** *: . .:*:*** : : * :: . : . : : ** : :*. . . : : : *** .: * .. . * .*. ***.*: . . .: :: ** ", "identical_positions": 26, "similar_positions": 47, "identity": "8.07%" }, { "cls_id": "homologset.agr.MGI:1261783", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9H0Q0-1", "uniprot_id": "CYRIA_HUMAN", "id": "Q9H0Q0-1", "name": "CYFIP-related Rac1 interactor A", "aln": "MGNLLKVLTR-EIENYPHFFLDFENAQPTEGEREIWNQISAVLQDSESILADLQAYKGAGPEIRDAIQNPNDIQLQEKAWNAVCPLVVRLKRFYEFSIRLEKALQSLLESLTCPPYTPTQHLEREQALAKEFAEILHFTLRFDELKMRNPAIQNDFSYYRRTISRNRINNMHLDIENEVNNEMANRMSLFYAEATPMLKTLSNATMHFVSENKTLPIENTTDCLSTMTSVCKVMLETPEYRSRFTSEETLMFCMRVMVGVIILYDHVHPVGAFCKTSKIDMKGCIKVLKEQAPDSVEGLLNALRFTTKHLNDESTSKQIRAMLQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BHZ0-1", "uniprot_id": "CYRIA_MOUSE", "id": "Q8BHZ0-1", "name": "CYFIP-related Rac1 interactor A", "aln": "MGNLLKVLTR-EIENYPHFFLDFENAQPTEGEREIWNQISAVLQDSESILTDLQAYKGAGPEIRDAIQNPNDIQLQEKAWNAVCPLVVRLKRFYEFSIRLEKALQSLLESLTCPPYTPTQHLEREQALAKEFAEILHFTLRFDELKMRNPAIQNDFSYYRRTISRNRINNMHLDIENEVNNEMANRMSLFYAEATPMLKTLSNATMHFVSENKTLPIENTTDCLSTMTSVCKVMLETPEYRSRFTSEETLMFCMRVMVGVIILYDHVHPVGAFCKTSKIDMKGCIKVLKEQAPDSVEGLLNALRFTTKHLNDESTSKQIRAMLQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M2B7R9-1", "uniprot_id": "A0A8M2B7R9_DANRE", "id": "A0A8M2B7R9-1", "name": "", "aln": "MGNLLKVLTCTDFDQGPNFFLDFENAQPTDCEREVWNQVNAVLQESESILSGLQAYKGAGQEIRDAIQNPNDMLLQERAWNSVCPLVIRLKKFYAFSLKLEQALQSLLESLTCPPYTPTQHLEREQALAKQFAEILHFTLRFDELKMRIPAIQNDFSYYRRTISRNRLNNMNLDIENEVNNEMANRMSLFYAEATPMLKTLSTATTNFVTENKTLPLENTTDCLSTMASVCKVMLETPEYTSRFNSEDTLLFCMRVMVGVIILYDHVHPNGAFNKSSKIDMKGCIKVLKDQPADNVEGLLNALKFTTKHLNDESTPKNIRTMLQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "********* :::: *:***********: ***:***:.****:*****:.******** ***********: ***:***:*****:***:** **::**:****************************:***************** ******************:***:******************************.** :**:******:**********:************ ***.**:**:****************** *** *:*************:*..*.********:***********.*:**:***", "identical_positions": 272, "similar_positions": 40, "identity": "83.95%" }, { "cls_id": "homologset.agr.MGI:1261791", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35431-1", "uniprot_id": "APBA2_RAT", "id": "O35431-1", "name": "Amyloid-beta A4 precursor protein-binding family A member 2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAHRKRQSTASSMLDH----------------RARPGPIPHD------------------------------------------QEPENE-----DTELPLESYVPTG----------------------------------------------------------------------------------------------------------LELGTLRPDSPTPEEQE--------------------------------------------------------------------------------------------------------------------------------------------------------------------------CHNHSPDGDSSSDYVNNTSEEE------------------------------------------------------------------DYDEG--LPEEEEGVTYYIRYCPEDDSYLEGMDCNG---------------------EEYLAHG-------------------AHPVDTDECQEAVEDWT----------------------DSVGPHTHSHGAENS---------------------------------------------------------------------QEYPD---SHLPIPEDDP------------------TVLEVH-------DQEEDGHYCPSKESYQ------------DYYPPETNG-------NTGGASPYRMRRGDG--DLEEQEEDID--------QIVAEIKMSLS----------------------MTSITSASEASP---EHMPELDPG---------------------DSTEACSPSDTGR-GPSRQEA--------RPKSLNLPPEVKHSGDPQRGLKT-----------------------------------------------------------------------KTRTPEERPKWPQ----EQVCNGLEQPRKQQRSDLN---------------------------GPTDNNNIPE-TKKVASFPSFVAVP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GPCEPED---------LIDGIIFAANYLGSTQLLSERNPSKNIRMMQAQEAVSRVKRMQKAAKIKKKANS-EGDAQTLTEVDLFISTQRIKVLNADTQETMMDHALRTISYIADIGNIVVLMARRRMPRSASQDCIETTPGAQEGKK------------------QYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPEDLS-QKEYSDIINTQEMYNDDLIHFSNSENCKELQLEKHKGEILGVVVVESGWGSILPTVILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVSCPPVTTVLIKRPDLKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEKIVQALSNSVGEIHMKTMPAAMFRLLTGQETPLYI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P98084-1", "uniprot_id": "APBA2_MOUSE", "id": "P98084-1", "name": "Amyloid-beta A4 precursor protein-binding family A member 2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAHRKRQSTASSMLDH----------------RARPGPIPHD------------------------------------------QEPESE-----DTELPLESYVPTG----------------------------------------------------------------------------------------------------------LELGTLRPESPTPEEQE--------------------------------------------------------------------------------------------------------------------------------------------------------------------------CHNHSPDGDSSSDYVNNTSEEE------------------------------------------------------------------DYDEG--LPEEEEGVTYYIRYCPEDDSYLEGMDCNG---------------------EEYIAHG-------------------AHPVDTDECQEAVEDWT----------------------DSVGPHTHSHGAENS---------------------------------------------------------------------QEYPD---GHLPIPEDDP------------------TVLEVH-------DQEEDGHYCSSKESYQ------------DYYPPETNG-------NTGGASPYRMRRGDG--DLEEQEEDID--------QIVAEIKMSLS----------------------MTSITSASEASP---EHMPELDPG---------------------DSTEACPPSDTGH-GPGRQEA--------RPKSLNLPPEVKHPGDLQRGLKT-----------------------------------------------------------------------KTRTPEERPKWPQ----EQVCNGLEQPRKQQRSDLN---------------------------GPTDNNNIPE-TKKVASFPSFVAVP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GPCEAED---------LIDGIIFAANYLGSTQLLSERNPSKNIRMMQAQEAVSRVKRMQKAAKIKKKANS-EGDAQTLTEVDLFISTQRIKVLNADTQETMMDHALRTISYIADIGNIVVLMARRRMPRSASQDCIETTPGAQEGKK------------------QYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPEDLS-QKEYSDIINTQEMYNDDLIHFSNSENCKELQLEKHKGEILGVVVVESGWGSILPTVILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVSCPPVTTVLIKRPDLKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEKIVQALSNSVGEIHMKTMPAAMFRLLTGQETPLYI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99767-1", "uniprot_id": "APBA2_HUMAN", "id": "Q99767-1", "name": "Amyloid-beta A4 precursor protein-binding family A member 2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAHRKLESVGSGMLDH----------------RVRPGPVPHS------------------------------------------QEPESE-----DMELPLEGYVPEG----------------------------------------------------------------------------------------------------------LELAALRPESPAPEEQE--------------------------------------------------------------------------------------------------------------------------------------------------------------------------CHNHSPDGDSSSDYVNNTSEEE------------------------------------------------------------------DYDEG--LPEEEEGITYYIRYCPEDDSYLEGMDCNG---------------------EEYLAHS-------------------AHPVDTDECQEAVEEWT----------------------DSAGPHPHGHEAEGS---------------------------------------------------------------------QDYPD---GQLPIPEDEP------------------SVLEAH-------DQEEDGHYCASKEGYQ------------DYYPEEANG-------NTG-ASPYRLRRGDG--DLEDQEEDID--------QIVAEIKMSLS----------------------MTSITSASEASP---EHGPEPGPE---------------------DSVEACPPIKASC-SPSRHEA--------RPKSLNLLPEAKHPGDPQRGFKP-----------------------------------------------------------------------KTRTPEERLKWPH----EQVCNGLEQPRKQQRSDLN---------------------------GPVDNNNIPE-TKKVASFPSFVAVP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GPCEPED---------LIDGIIFAANYLGSTQLLSERNPSKNIRMMQAQEAVSRVKRMQKAAKIKKKANS-EGDAQTLTEVDLFISTQRIKVLNADTQETMMDHALRTISYIADIGNIVVLMARRRMPRSASQDCIETTPGAQEGKK------------------QYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPEDLS-QKEYSDIINTQEMYNDDLIHFSNSENCKELQLEKHKGEILGVVVVESGWGSILPTVILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVSCPPVTTVLIKRPDLKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEKIVQALSNSVGEIHMKTMPAAMFRLLTGQETPLYI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BG86-1", "uniprot_id": "A0A8M2BG86_DANRE", "id": "A0A8M2BG86-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAQRKRPGINSGMATEPHAP----------APRSCPAPYPDP------------------------------------------EHPEEEYEEHHDPEVTQHSYHNQEE---------------------------------------------------------------------------------------------------------ADLTDSRPTTPTTPDHAHRD---------------------------------------------------------------------------------------------------------------------------------------------------------------------YHSHPDSLDGDSSSDYVNNTSDEEED----------------------------------------------------------------DFDEG--LPEEDEGVTYYIRYCPEDDSYLEGMDCND---------------------PEYVHPDG----------------RMEPPPDTDECQEAVEEWVE------------------GEDDAQGDEDDDDEEDDDDDDDGEVRCEVLEQDSDQQLYDGRPEP--------------------------------VLDHHHH---QHYTDPHQEQLPPPIEDQ------------------EVKDVEGSERYCPDQEEEPQVGRDREGYAG-----------DYYATEDNG-------NSVRASPYRGHKGTEGETGEEAEEDID--------QIVAEIKMSMS----------------------MGSLSSGTDQSPE--ELAPDPAPSGYQP-----------------ETRSKPEPAPAPYPQPHRHDG--------RPKSLNIPPARHNP-ELQRNFKV-----------------------------------------------------------------------RPHTPEDRQRWTQDQVREQMSNSAEQPRKQQRSDLN---------------------------GPLENNNVTEPTKKTASFPSFVDVP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GPCEPED---------LIDGIIFAANYLGSTQLLSERNPSKNIRMMQAQEAVSRVKRVQKAAKIKKKAQSPEGDAQTLTEVDLFISTQRIKVLNADTQETMMDNALRTISYIADIGNIVVLMARRRMPRTASQDCIETTPGAPEAKK------------------QYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPEDLS-QKEYSDIINTQEMYNDDLIHFSNSDNCKELQLEKQKGEILGIVIVESGWGSILPTVILANMMNGGPAARSGKLSIGDQIMSINNTSLVGLPLATCQGIIKGLKNQVQVKLNIVSCPPVTTVLIKRPDLKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEKIVQALSNSVGEIHMKTMPAAMFRLLTGQETPMYI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9PZ33-1", "uniprot_id": "A0A8M9PZ33_DANRE", "id": "A0A8M9PZ33-1", "name": "Amyloid-beta A4 precursor protein-binding family A member 3", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAFKRRPETRSVAAELN---------------PPAFSAVPEG------------------------------------------REQLSG---DRDDPVLEEAEHDKLD---------------------------------------------------------------------------------------------------------CQTPSPTPAQYSLSDESGDDSIRG----------------------------------------------------------------------------------------------------------------------------------------------------------------ESPLQPDSMEEDSLSEYDNVGSGDEQEE------------------------------------------------------------VERDYEEDEELQTEADRMTYYVHCCPEDESYMEGLDCHEGADGAECPSTSQDVRESCKPKEAWEHSDTSLCKGQQKDAATMVYKQPEPITETTFVQAPMAEDEE------------------DEEETEEDVEEEDSEEEDNGGFFHYEGNEAELNNNEIPHKDNCSN--------------------------------VCRREGKSPPQEFSRVKVGQESRRSQDN------------------PKYSRDVPLGSNCTQRDRMERVRDKNGSDCPKVS------NAPVARESRK-------DSRQNFKYRGHHLETKNNRETAYQGHS--------AVTIKGKSADAEDRGTWKKRHLLKYSREDARGGDGNNSHKRSKSPENCKNRPQDHPICSHKSNGENERKISGNVEARIENEVKTKLIIAPNNSGRTKVA--------PDQAKNVKGAPESPRASSASSGK-----------------------------------------------------------------------RNSKPRGQANTPVQSPAKQVNKDSAKPVEEEKTRPNEEQVSQS-------------ASQDSSTGPPSGQNRPQ-TQRNPSFPSFVDIP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GPCEPED---------LINGIIFAANYLGSTQLLSDRNPSKSVRMKQAQEAVDCVK-------------AVEVETQSLTEIDLFISTKAIKVLNADTQETMMDNALRTISYIADIGNVVVLMARRRLS-NSSLDCTESGLNSDANHK------------------QYRMICYVFESEDAQLIAQSIGQAFSMAYQEFLRANGINPKDLS-QKDYSDILNTQEMYNDDLVHFSNSDNCKQLHLEKQKGEILGVVIVESGWGSILPTVILACMLNNGPAARSGKLNVGDQIMAVNDTSLVGLPLAACQGIIKALKNHVQVKLSVVSCPPVTTVLIKRPDLQYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVAMAHEKIVHALSVSVGEINMKTMPAVMFRLLTGQETPVYM", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "X2JE74-1", "uniprot_id": "X2JE74_DROME", "id": "X2JE74-1", "name": "", "aln": "--------------------------------------------------------------------MNSNSCSDSSNE---------------------SMVNPP-----HIQMNFG-----QQAQQQQSHQHQQQQQQQ--------ERYVWEMRTRS-----------------------------PNVTPASTVLN------------SPDLNGELSYVPLQGLSP---------------------------------------------------------------------------------SGGGVQGSGSYGSNAGRDS----------------------------------------------------------------------------------GSYYYQR-------------PQLHQIRLGRSPGS-----------------------QFETRDVLPQGLASP--------------GSPTDVGKADG----------------------------------------QCLRDGEIVVFDDIDTNWMNKASSGQR---------------------------------PGSNEDVLKVT----------------KMIGQLP------------------------------------IAEYEGSPRRFGSQPNTNTITMGGPRK-----------------------RP------------------------------------------------------------------------PGFPQRVSP------------------------------------TTSVANN----------------ATAAAKASVGNLIDLVDHEEE-------------------------------------RSG------------------TLREKTPTFDYLYEFSETRKVLEEFFKANPEDEKRYTDYTTESG-----------------DDVASSQPQE-----------------YPATPMEQAYIGQRLARIPK-----DELYMVHR----SPTKKPPSDQNPSTAYQEHN-------DIELYIDSNSRSSGD-------LADTELEANLRRHS----------------RNFTLSPETTDYDSNCGDLDSLSNDIN-----CPTDFGKLYTS-MPVLEDGLSSGHASDTENNVSVVCDKQQSSQSQP---------VHEHNGNG--------ERLENDYNVMSAS----LATLTTDAS------QSALISDFASLPMP-------PAPPPSSPPQIEIADASES--MTMVPDADNPLDSHYGA----------VYAAALGGTHTEKSAGSGLGVTPVTAGGSLPS--------QAASEIQEAMKEIRSALQRAKTQ----------------------------------PEKLKFCDEVLPTD---PDSPVWVPR------------KGTTISTAQGAAADEEPDTDLETDRLLGQQRHDEQDFFADQSLADNN-ANEGTDIASNGHLNGTSDNNNPNPMNNSKPQTYSTATIR--QGIGTSLTP---NSPDICQIVG-------------------------------------------TTDISISSPEKLQFTKSPTGSIKSLKDSAN-------------------------------------------------------------------SDKKAKSRNKEGLLEPK---------VLIEGVLFRARYLGSTQLVCEGQPTKSTRMMQAEEAVSRIK-----------ALAPEGESQPSTEVDLFISTEKIMVLNTDLKEIMMDHALRTISYIADIGDLVVLMARRRFVPNSVVDPSITSPLGDVPTPGIGEEESPPKEPLSKHNRTPKMICHVFESDEAQFIAQSIGQAFQVAYMEFLKANGIENESLAKEMDYQEVLNSQEIFGDELEIFAKKELQKEVVVPKAKGEILGVVIVESGWGSMLPTVVIANLMSSGAAARCGQLNIGDQLIAINGMSLVGLPLSTCQSYIRNAKNQTAVKFTVVPCPPVVEVKILRPKALFQLGFSVQNGVICSLLRGGIAERGGVRVGHRIIEINNQSVVAVPHDTIVKLLSSSVGEILMKTMPTSMFRLLTGQETPIYI", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W2S5-1", "uniprot_id": "Q9W2S5_DROME", "id": "Q9W2S5-1", "name": "", "aln": "MVSTTLTTLAAGQTTSSSNHHHHHHHSHQQQQQQQQQDQSQQQPHQQLPYQQRGYYALNGSLELDCDTSNTNSSSSSNNIGYQQHQQQQQQQQQPPLILSQALLSPSPPLNDQISLLFPKCRPKQQQQQQQQQQQQQQQQQQQLQPAQQHQQHVHPTDVNSSCNSNRSSSPTTAGAVGEPLASVSVSPPPPKATPTSSTPSYYKSVNIITQSPPPHSASSHSSESLSSVTPRISTNPFLCAPLTPPTPPHHHHHHHHQQQHQQKQQQPKQQHQTQQQEQQEEDTTGESVVEHSRSGAAGEVLEYPASFYYHTVGDSRRGPGSYTEMPRKRSSALPASNRQQQLHNGNGSQNPFIKENYWEAPPTRASLLLHSPTEYSEEPQQQQQIQQQQQQQQQQQQQQQQQQQQHLHASARRAYHQQREQVYGINQRPQQQQQQNILRVGRSPVNRSFPQQHQQQQQQQQQQQQQQQQQQQPHQQIPTARSNPCADGLTPLASHYLYGSKSSLDQHPGDWEPREQRKLRLREEREREREREREREREREREHLLLEQQQQLQLQEVQVARDNHLSHLAGQQQQQQQRKRHVYGEERERERDRERDMDRDHRLVNGNADPNESWQHLRVTTETLAEEGGKHGKPADKAQHQMHNTNQSQNSDVNVYREHQLDAWKLERSYTLAVESRHGIIEYEGSPRRIGVTTTSNLGATGAAAASAAADESEPPAAAEGAAAATATSQPQQQVPMATVPPLSSTATSLQKTAARAALAALAQSHPHSSHNILSTLLPHSPNPVNPGQMHAAQQSIQNYPVRPGFPQRIISPPSRDPRSSSPPLQQQQYQQQQQQQLQHQQQHFASLMSSHSNNNSNTNKQPLSSDNNAEDTSNDVSEIGTISDLTTPEAVGLSIGIAAGEMASRASTPPQTAQAPPTAVAGSTANGTGSGNGTATGNATAAGSGLGPLSLHTKSSTFDYLYEFSETRKVLEEFFKCPSTDEQPIMENGSDVDSIDIQYEFHSNFERDE-EDLAEEEEAEDDEEVDDDADEENDEAEDEDEPLEQDRDQNYRAQAPPQSGHIDSERLVYSGYGQQPQLQAQLTAQPMSGARRHYSGSPLMRDFDFFLDSTSRSSGERDADQDGLNHNQLLSTSSGHGGGVGVSGGLGVGPGGGHNYRYSPETTDYDSNCGDLDSLSGEMNGGVSTSCSNYAKFYASAMPVLEDGLSSGHTSDTENNNNNQKNLQQSTVNQGGQCPTSLSGSTSIGGSGGISMLMDMKRISTNHSLNSMNNQTTTASTTTDSNGGVGGVGHHLVATLVASPNNEQAKSQCQTQLQSHPPKTLSLDQSPSNHSKVFKNIDPELDSLYSIGVFHRPDTVQMTPPPPAPAPHRKPNNNGCSSGVVNTNGSLAGGSNDVDLLQPSSKHTPLAAAISSTLQRSSPTSTITGNGIGNGSGKTRSAGSNCSSSANGGMPPPIPERTNLVSAVQRSPSPGPNSPVWLSRHLDGGAGKDLLESGSDNHSKNHSADEEDVDTDLETDRLLGHQRLDDQGYYDENKSWDRKPRSLLSKISPKQQIPSTKTRNGYNALLSSTPELPPPIPPKGQSGLGLGLTLGAGNGGKLLDLVGGMVQRSLSRSSSEHSEKSLSKMPISGGDLCAGGVDVVASTVAATSATVVASTPALGSPGNGGGSERSAAEMANPGGAVKLSEQEIGTINGGSVMPLGSGSGTGSGAGSGAGSGTGTNAAVVANSNANNNVGGGGGGGNNSSGSGAGSNSNSGEKKVKKSKSKEGGAVLIEGVLFRAKYLGSTQLVCEGQPTKSTRMMQAEEAVSRIK-----------ALAPDGDVQPSTEVDLFISTEKIMVLNTDLKEIMMDHALRTISYIADIGDLVVLMARRRFVP---------QDIDDAPKP----------------NRTPKMICHVFESDEAQFIAQSIGQAFQVAYMEFLKANGIEDHRFVKEMDYQEVLNSQEIFGDELEIFAKKELQKEVVVPKAKGEILGVVIVESGWGSMLPTVVIANLMSSGAAARCGQLNIGDQLIAINGLSLVGLPLSTCQTYIKNTKNQTVVKFTVVPCAPVVEVKIKRPETKYQLGFSVQNGVICSLLRGGIAERGGVRVGHRIIEINNQSVVAVPHEKIVNLLATSVGEILMKTMPTSMFRLLTGQENPIYI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . : . : : . . : : :: : . : :.: . *:. . : .. .: . : . .: . : : . . : . : . . . : . . . . : : .:: : .. :. . .. . * : : **:*::* *.*******:.: :*:*. ** **:***. :* : : : *. **:******: * ***:* :* ***:************::********: :***:****::**:*********.:** ***:****: . : : :*.:::*:**::.*:* *::.: *:: : * ******:*:*******:****::* ::..*.***.*:*.:***::::*. *******::** *: **:. **:.:*.*.**. * * **. :*********:****:********************.***** .*:.**: *: ***** *****: *********.*:*:", "identical_positions": 212, "similar_positions": 163, "identity": "9.74%" }, { "cls_id": "homologset.agr.MGI:1261794", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AYC0-1", "uniprot_id": "Q6AYC0_RAT", "id": "Q6AYC0-1", "name": "", "aln": "---MASGDFCSPGEGVEILQQVCDKQFPPCALTEEDLIQNPYFSKLLLSLSQHVDESGLSLPLAKEQAQAWSEVRLRKTAWLRYEILQRVIQELLVDYYVKAQDTNLTSEDKK--FHETLEQRLLVTELTQLSGPGREKEMPP--LLGLEKADLLELMPPSQDFVWMKARLQQEVEEQLKRKCFSLLCYHDPSSDTDGDKLKAAKVWTLTEVLVREKQQCMEAKGQQKEQLVLLEKKRTTYSQVLLRCLSLLQRLLQEHRLKTQSELDRINTQYLEIKCSAMILKMRMEELKILSDTYSAEKVEVHRLIRDHLEGAIRLQEQDMEKSRLALHTYEVLGEDFENLVKEYTQLKLAAENKRWALQEFSKAYR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BFT2-1", "uniprot_id": "HAUS4_MOUSE", "id": "Q8BFT2-1", "name": "HAUS augmin-like complex subunit 4", "aln": "---MASGDFCAPGEGVEMLLQVCGKQFPPCALTEEDLIQNPRFSKLLLSLSQHVDESGLSLTLAKEQAQAWSEVRHRKTAWLRYEILQRVIQELLVDYYVKAQDTNLTSEDKK--FHETLEQRLLVTELTQLSGPGQETELPP--LLGLERTDLLELMPPSQDFVWMKARLQLEVEEQLKRKCFTLLCYHDPSSDTDGDTLKAAKVWTLTEVLVREKQQCLEAKSQQKEQLVLLEKKRTTYSQVLLRCLALLQRLLQEHRLQTKSELDRINAQYLELKCSAMILRLRMEELKVLSDTYSAEKVEMHRLIRDRLEGAIRLQEQDLEKSRLVLHTYEALGEDFESLVREYTQLRLAADNKRWALQELSKAQR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H6D7-1", "uniprot_id": "HAUS4_HUMAN", "id": "Q9H6D7-1", "name": "HAUS augmin-like complex subunit 4", "aln": "---MASGDFCSPGEGMEILQQVCSKQLPPCNLSKEDLLQNPYFSKLLLNLSQHVDESGLSLTLAKEQAQAWKEVRLHKTTWLRSEILHRVIQELLVDYYVKIQDTNVTSEDKK--FHETLEQRLLVTELMRLLGPSQEREIPP--LLGLEKADLLELMPLSEDFVWMRARLQQEVEEQLKKKCFTLLCYYDPNSDADSETVKAAKVWKLAEVLVGEQQQCQDAKSQQKEQMLLLEKKSAAYSQVLLRCLTLLQRLLQEHRLKTQSELDRINAQYLEVKCGAMILKLRMEELKILSDTYTVEKVEVHRLIRDRLEGAIHLQEQDMENSRQVLNSYEVLGEEFDRLVKEYTVLKQATENKRWALQEFSKVYR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q325-1", "uniprot_id": "A0A8M9Q325_DANRE", "id": "A0A8M9Q325-1", "name": "", "aln": "MSQRNDCVFASSLGKGDHLHQQVLAAFPLCQMTEEDLIQNPQFCKLLATLSQHVDRTGLTQHLRRDLEKAERELHTQRLSWLRVESIHRLLREIIQENHFSKASSAQTGDATVPHFYSTLEQCLMVGQCVKRMDISADVSEPHSGILGLTAERVKRLMPSEQDVLQMKQKCPSELLQHLKKKSVAILTYYQPDWENESEGLRSVKLSKLPELLDGEKKKVKSLTEKNRENTTLLQRQTHTYLSELLMCMKILQSLVLELRLKAQKDLDRKKIEYFEGKCEIGLQKIRAEMLEVQLDTYTRDKIATHKKITEKLNADLKSSKMEKQEVESKLASFEIYGKDFEALAEEYSRLRQEIATKSWALKEFSTSNT", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *.:. : * * :* * :::***:*** *.*** .******.:**: * :: :* *:: :: :*** * ::*:::*:: : :.. .: *.: . *:.**** *:* : : . . : . * :*** : .*** .:*.: *: : *: ::**:*..::* *::*. : :.: :::.*: .*.*:* *::: . . :::*: **::: :* . ** *: :** *: * **:::.:*** : :*:* ** : ::* * *:: ***: :*: *: * ::*:. :: .: : :: . * ::* *::*: *..**: *: .* ***:*:*. ", "identical_positions": 105, "similar_positions": 139, "identity": "28.38%" }, { "cls_id": "homologset.agr.MGI:1261797", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D211-1", "uniprot_id": "C2AIL_MOUSE", "id": "Q9D211-1", "name": "CDKN2AIP N-terminal-like protein", "aln": "MVGGEASAAVEKLVSGVRQAADFAEQFRSYSESEKQWKARMEFILRHLPDYRDPPDGGGRLDQLLSLSMVWANHLFLGCSYNKDLLDKVMEMADGIEVEDLPQFTTRSELMRKHQS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5RK03-1", "uniprot_id": "C2AIL_RAT", "id": "Q5RK03-1", "name": "CDKN2AIP N-terminal-like protein", "aln": "MVGGEATSAVEKLVSGVRQAADFAEQFRSYSESEKQWKARMEFILRHLPDYRDPPDGGGRLDQLLSLSMVWANHLFLGCSYNKDLLDKVMEMADGIEVEDLPQFTSRSELMKKHQS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96HQ2-1", "uniprot_id": "C2AIL_HUMAN", "id": "Q96HQ2-1", "name": "CDKN2AIP N-terminal-like protein", "aln": "MVGGEAAAAVEELVSGVRQAADFAEQFRSYSESEKQWKARMEFILRHLPDYRDPPDGSGRLDQLLSLSMVWANHLFLGCSYNKDLLDKVMEMADGIEVEDLPQFTTRSELMKKHQS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******::***:*********************************************.***********************************************:*****:****", "identical_positions": 110, "similar_positions": 6, "identity": "94.83%" }, { "cls_id": "homologset.agr.MGI:1261809", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O55230-1", "uniprot_id": "RA51D_MOUSE", "id": "O55230-1", "name": "DNA repair protein RAD51 homolog 4", "aln": "--MGMLRAGLCPG--LTEETVQLLRGRKIKTVADLAAADLEEVAQKCGLSYKALVALRRVLLAQFSAFPLNGADLYEELKTSTAILSTGIGSLDKLLD---AGLYTGEVTEIVGGPGSGKTQVCLCVAANVAHSLQQNVLYVDSNGGMTASRLLQLLQARTQDEEKQASALQRIQVVRSFDIFRMLDMLQDLRGTIAQQEATSSGAVKVVIVDSVTAVVAPLLGGQQREG-LALMMQLARELKILARDLGVAVVVTNHLTRDWDGRRFKPALGRSWSFVPSTRILLDVTEGAGTLGSSQRTVCLTKSPR-----QPTGLQEMIDIGTLGTEEQSPELPGKQT----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75771-1", "uniprot_id": "RA51D_HUMAN", "id": "O75771-1", "name": "DNA repair protein RAD51 homolog 4", "aln": "--MGVLRVGLCPG--LTEEMIQLLRSHRIKTVVDLVSADLEEVAQKCGLSYKALVALRRVLLAQFSAFPVNGADLYEELKTSTAILSTGIGSLDKLLD---AGLYTGEVTEIVGGPGSGKTQVCLCMAANVAHGLQQNVLYVDSNGGLTASRLLQLLQAKTQDEEEQAEALRRIQVVHAFDIFQMLDVLQELRGTVAQQVTGSSGTVKVVVVDSVTAVVSPLLGGQQREG-LALMMQLARELKTLARDLGMAVVVTNHITRDRDSGRLKPALGRSWSFVPSTRILLDTIEGAGASGG-RRMACLAKSSR-----QPTGFQEMVDIGTWGTSEQSATLQGDQT----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1R474-1", "uniprot_id": "F1R474_DANRE", "id": "F1R474-1", "name": "DNA repair protein", "aln": "--MVVLREGICPG--INEDFIKALQTEDIRTVEDFVSWNPEELAQKCSLSYKALVAVRRVLLAQYTAYPISGADLYEELLSSTAILSTGSPSLDKLLD---SGLYTGEITELTGSPGSGKTQVCFSVAVNISHQLKQTVVYIDTKGGMCANRLLQMLQTKTSNEQEQMEALQKIKVFRVFDVFSLLACLQNLRSTGLQKTSVGGGSVKALMVDSVSAVLSPILGGKQNEG-MSLLMQVAGELKMIAKDFNIAVLVTNHVTKDGNG-QLKAGLGLSWSHVPRTRVLLQRVENE--ETSSLRTATLTKSSR-----QACHMTKVFDLCHW-SEERTTSISGKRKLD--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z7R8-1", "uniprot_id": "A1Z7R8_DROME", "id": "A1Z7R8-1", "name": "", "aln": "MDLRPMILQTCTGRLLSEYQLNLLRKNNICSLIDFYDADEKKLHELWAINIQSVRELKKELSLLPKGSVDEG--------TPDFNYDTGIEELDKLLDSVEQPFKPGRVWELCGQPGVGKTQLLYTLALNFVWKHSQAVLFIDTKREFSCKRIQDMLRAREVDEEASERAMKGIRVVQAATGADINDLLKSFDHQLTAETHAS-MQTKLVLIDSLAACFAFYRGRRMRDVRKSVLTELACKIRKLALR-GVAFVIGNVSFFENNKDSCGDDGEQNGDDEEVTRQQLEPMLGSYWSSVATLRLSVELPEEEDFTLQDDGLRFIYVISNTYGPDGEHCLLRITDAGVV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : *.* :.* :: *: . * :: *: : ::: : .:. ::: ::: * .. .* :. .** .****** : .*.: *: * ** ****: :* *. .* *:::*:: : ..*: ::*::: :*: . *:: *:*.: : *:.: : . .* :::**::* .: * : .: ::: ::* ::: :* .:*.:: * : : . . ** *: . : . . * : : : : : ", "identical_positions": 50, "similar_positions": 109, "identity": "14.45%" }, { "cls_id": "homologset.agr.MGI:1261811", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K1F7-1", "uniprot_id": "A0A0G2K1F7_RAT", "id": "A0A0G2K1F7-1", "name": "Unconventional myosin-XV", "aln": "MAKEEDEEKKAKKGKKGKKAPEPEKPKRSLKGTSRLFMGFRDRTPKISKKGQFRSASAFFWGLHTGPQKTKRKKKARTVLKSTSKLMTQMRVGKKKRAMKGKKPSFMVIRFPGRRGYGRLRPRAQSLSKASTAINWLTKKFLLKKAEESGSEQATLDAWLQRSSSRVGSRKLPFPSGAEILRHGGRLRRFPRSHSIYSSGEPVGFLPFEDEAPFRHAGSRKSLYGLEGFQDLGEYYDYHREGDDYYDQQSLYHYEEQEPYLAGFGGYSPAWPPYDD--YGYPSGDPYNYYHPDYYGDTLYPAYGYGYGYGYDDLEPPYAPPSGYSSPYSYHDSFEDEAYPYSYYLDPYATHHMPYPPYDFPHDTPYDIPYFDPYG----VPYAEGIYGGGAEAIYPPGVPYVYPEE--PAFMYPWVPPPIMSPHNPYAHPMDDIAELEEPEEIGRERQSTSFRLPSAAFFEQQGMDKPARSKLSLIRKFRLFPRPQVKLFGKEKLEVPLPPSLDIPLPLGDAEGEEEEEEMPPVPTMPYTHPYWSFLTPRQRNLQRALSAFGARQGLG-FGPEFGPPTPRPATSLARFLKKTLSEKKPIPRLRGSQKARGGRPPVREAAYKRFGYKLAGMDPDRPNTPIVLRRSQPQARNNNNSHGPPSPRPAPRTLTHWSALISPPMPGPSPSPASPLTPPFSPPLSRPPRLASPYSSPYGSLRQHPPPWAAPAHVPFPLQANWWGFAEPPGTSPEVAPDLMAFPVPRPSFRASRSRG--AAYGFPRPSLIGSRRRPH--LPSPQPSLRSLPGQGYHSPLGHLSPQLSLRRGPFQPPFPPPPRRPQSLRETFSLHRTSGRLGPPRSPVLGSPRPPSPPPLLKH-PRHRSLNLPSRLPRTWRRLSEPPTRAVKPWIHRAYHPPPSAGPWGATAGSLEHQENQREPEDSETPWTVPPLAPSWDVDMATTQRPPSPWPEGVGSLRGFSRPPPVPENPLLEHTSPSCEP--RPEDQASNLTGIFLGQHHDPGPGQLTKSANPSLENPEEVVISEDPQPSAEPETLN-TPPN-----------KTVVSERKALRPSASYPLVTCKQSRATWPQWHRWKTVSRTPAPLAPTRAPGSLLKAGKQLRDKPGRFAVVMPQVRGLSSFQQKGSAPLQPPEHSDQDPEHGPATQACSLRWPRLWSPADTHSPWPRIHTLSSPSPLRGHGGDCQSPKDLWKKTGSRSWQNKMHSIRNLPSVRSREQHREDGVEDMTQLEDLQETTVLTNLKTRFERNLIYTYIGSILVSVNPYRMFAIYGPEQVQQYSGRALGENPPHLFAIANLAFAKMLDAKQNQCVIISGESGSGKTEATKLLLRCLAAMNQRRDVMQQIKILEATPLLEAFGNAKTVRNDNSSRFGKFVEIFLEGGVICGAITSQYLLEKSRIVFQAKNERNYHIFYELLAGLPAQLRQAFSLQEAETYYYLNQGGNCEIAGKSDADDFRRLLAAMEVLGFTSEDQDSIFRILASILHLGNVYFEKHETDAQEVASVVSAREIQAVAELLQVSPEGLQKAITFKVTETIREKIFTPLTVESAVDARDAIAKVLYALLFGWLITRVNALVSPKQDTLSIAILDIYGFEDLSFNSFEQLCINYANENLQYLFNKIVFQEEQEEYIREQMDWREIAFADNQPCINLISLKPYGILRILDDQCCFPQATDHTFLQKCHYHHGANPLYCKPKMP-LPEFTIKHYAGKVTYQVHKFLDKNHDQVRQDVLDLFVHSRTRVVAHLFSSHAAQTAPPRLGKSSSITRLYKAHTVAAKFQQSLLDLVEKMERCNPLFVRCLKPNHKKEPGLFEPDVMMAQLRYSGVLETVRIRKEGFPVRLPFQVFIDRYRCLVALKLNVPADGDMCVSLLSRLCTVTPDMYRVGVSKLFLKEHLHQLLESMRERVLNRAALTLQRYLRGFFTQRRFRSLRQKIILLQSRARGFLARQRYQQMRQSLLKFRSLVHTYVNRRRYLKLRAERRRRAQEAWLREQEELSKREVVPVRHLEVPAEVAGLLQAAAGLKPSSVPQVAIVRAPRLQAEPCVTLPLDINNYPMAKFIRCHFKEPSFGMLTVPLKMPLTQMLVEHHAEAISVFKLILRFMGDPHLHGTQEMILGNYIVHQGLVEPALRDEILAQLANQVWRNPNAYNAKRGWLLLAACLSGFAPSSHLDKFLLKFVSDYGQNGFQAVCQHRLLQAMG------SGAARTFPPTQLEWTAIQEKASMALDVSCFNGDQFSCPVHPWSTGEAVAGDILKHRGLADGWRGWTVAMKNGVQWAELAGHDYVLDLVSDLELLRDFPRQKSYFIVGAEGPLAGRGDTRGVFGNCWDSDEDTPTRPQPQDHVAKMPDFDGYCSHKEDGTNGETAAQRWASNRQAVDNTGEPAVPPRELDGYLDSLFDPVLACGDVDLEKPTAIAYRMKGGGQPGS---SASEDTPRRLPEPKLKPIPGLDASTLALQQAFIHRQAVLLAREMTLQALALQQQPLSATSRPQLPERPLPPEARPKTVG-TGPPAKPVLVRPTPQSLAPGSVAKSPKIPSKP---VAAPILARDWTAPESISSSPELVRYSTLNSEHFPQPTQQIKSIIKQYKQPPWAGHPEARRTDGGKVFRRPPDPHEEALMILKGQKTQLAVVPGTQVSREAVALVKPVTSAPRPCMGAAPVQPSRSLEPPEDPVQTQLHRLVNPN-FYGYQDAPWRIFLRKEVFYPKDNYSHPVQLDLLFRQILHDTLSEACLRISEDERLQMKALFAQNQLDTQRPLVTESVKRAAINMARDSWEIYFSRLFPAMGSVGTGVQILAVSHTGVKLLRMAKGNREASRRLRVLCAYSFADILFVTMPSQNMLEFNLTNEKVILFSARARQVKTLVDTFILELKKDSDYVVAVRNFLSEDPELLSFHKGDIIHLQSLEPPRIGYSAGCVVRKKLVYLEELRRRGPDFGWRFGAVHGRVGRFPSELVQPAAAPDFLQLPAEPGRGRAAAVAAAVASAAAAREVGRRREGPPVRARSADSGEDSVALPPSTMLEFAQKYFRDPRRRPRDGLKLKSKEDRESKTLEDMLCFTKVPIQESLIELSDSNLNKMAVDMFVAVMRFMGDAPLK-GQNELDVLCTLLKFCGDHEVMRDECYCQIVKQITDNTSSKQDSCQRGWRLLYILAAYYSCSEVFYPYLIRFLQHVSWTPGLPFQGIAKACEQNLQKTLRFGGRLEFPSSMELRAMLAGRSSKRQLFLLPGGLERHLKIKTCTVALDVIEGLCSEMALTRPEAFDEYVIFVVTNRGQHVCPLSCQAYILDVASGMEQVDGGYTLWFRRVLWDQPLKFEN---ELYVTMHYNQVLPDYLKGLFSSVPAS-QPTEQQLQQVSKLASLQHRAKDHFYLPSVREVQEYIPAQLY--HTTAGDTWLNLVSQHRQQTQALSPHQARAQFLGLLSAFPLFGSSFFFIQSCSN----------VLVPAPCILAVNHNGLNFLSTKTHELIVKIPLKEIQSTWTQQPTANSSYPYVEISLGDVAAQRTMQLQLEQGLELCRVVAVHVESMLSAREERLTLPPSEITLL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QZZ4-1", "uniprot_id": "MYO15_MOUSE", "id": "Q9QZZ4-1", "name": "Unconventional myosin-XV", "aln": "---MADEEKKAKKGKKGKKAPEPEKPKRSLKGTSRLFMGFRDRTPKISKKGQFRSASAFFWGLHTGPQKTKRKKKARTVLKSTSKLMTQMRVGKKKRAMKGKKPSFMVIRFPGRRGYGRLRPRAQSLSKASTAINWLTKKFLLKKAEESGSEQATVDAWLQRSSSRVGSRKLPFPSGAEILRHGGRLRRFPRSHSIYSSGEPVGFLPFEDEAPFRHAGSRKSLYGLEGFQDLGEYYDYHREGDDYYDQQSLYHYEEQEPYLAEFGGYSPAWPPYDD--YGYPPGDPYNYYHPDYYGDTLYPGYAYGYGYGYDDFEPPYAPPSGYSSPYSYHDSFESEAYPYSYYLDPYATHHMPYPPYDFPYDTPYDIPYFDPYG----VPYAEGVYGGGAEAIYPPGMPYVYPEE--PAFMYPWVPPPIMSPHNPYAHPMDDIAELEEPEETGEERQSTSFRLPSAAFFEQQGMDKPARSKLSLIRKFRLFPRPQVKLFGKEKLEVPLPPSLDIPLPLGDAEGEEEEEEMPPVPTMPYTHPYWSFLTPRQRNLQRALSAFGARQGLG-FGPEFGHPTPRPATSLARFLKKTLSEKKPIPRLRGSQKARGGRPPVREAAYKRFGYKLAGMDPDRPNTPIVLRRSQPQARNNNNSHGPPSPRPAPRALTHWSALISPPMPAPSPSPASPLTPPFSPTFSRPPRLAS----PYGSLRQHPPPWAAPAHVPFPPQANWWGFAEPPGTSPEVAPDLLAFPVPRPSFRASRSRSRRAAYGFPSPSLIGSRRRPH--LPSPQPSLRSLPGQGYHSPLGPLSPQLSLRRGPFQPPFPPPPRRPQSLREAFSLRRASGRLGPPRSPVLGSPRPPSPPPLLKHGPRHRSLNLPSRLPRTWRRLSEPPTRAVKPWVHRAYPPPPSAGPWGASTGALEQQENQREAEDSETPWTVPPLAPSWDVDMPPTQRPPSPWPEGIGSLRGFSRPPPVPENPLLEHTSPSCEP--QSEDRVSNLTGIFLGQHHDPGPGQLTKSADPSLEKPEEVVTLGDPQPPAEPEALNPTPPN-----------KNVVSERKVLRLSASYPLVTCKQARATWPQWHRWKTVSRTPAPLAPTRAPGPLLKAGEQPRAEPGRFAVVMPQVRGVSSFRPKGPAPVQPPEHPDQDPEQGPAPQACSLRWPRLWPPTDAHCLWSRIRTYSSQSHLRGHGGDCH--KSLWKKTRPQSWQNKMHSIRNLPSMRSREQHREDGVEDMTQLEDLQETTVLANLKTRFERNLIYTYIGSILVSVNPYRMFAIYGPEQVQQYSGRALGENPPHLFAIANLAFAKMLDAKQNQCVIISGESGSGKTEATKLILRCLAAMNQRRDVMQQIKILEATPLLEAFGNAKTVRNDNSSRFGKFVEIFLEGGVICGAITSQYLLEKSRIVFQAKNERNYHIFYELLAGLPAQLRQAFSLQEAETYYYLNQGGNCEIAGKSDADDFRRLLAAMEVLGFTSEDQDSIFRILASILHLGNVYFEKHETDAQEVASVVSAREIQAVAELLQVSPEGLQKAITFKVTETIREKIFTPLTVESAVDARDAIAKVLYALLFGWLITRVNALVSPKQDTLSIAILDIYGFEDLSFNSFEQLCINYANENLQYLFNKIVFQEEQEEYIREQMDWREIAFADNQPCINLISLKPYGILRILDDQCCFPQATDHTFLQKCHYHHGANPLYSKPKMP-LPEFTIKHYAGKVTYQVHKFLDKNHDQVRQDVLDLFVHSRTRVVAHLFSSHAAQTAPPRLGKSSSITRLYKAHTVAAKFQQSLLDLVEKMERCNPLFVRCLKPNHKKEPGLFEPDVMMAQLRYSGVLETVRIRKEGFPVRLPFQVFIDRYRCLVALKLNVPADGDMCVSLLSRLCTVTPDMYRVGISKLFLKEHLHQLLESMRERVQNRAALTLQRYLRGFFIQRHFRSLRRKIILLQSRARGFLARQRYQQMRQSLLKFRSLVHTYVNRRRYLKLRAEQRRRAQEAWLREQEELSKREVVPVRHLEVPAEVAGLLQAAAGLKLSSGPRVAVVRAPRLQAEPCVTLPLDINNYPMAKFIRCHFKEPSFGMLTVPLKMPLTRLPVEHHAEAISVFKLILRFMGDPHLHGTQEMILGNYIVHQGLVEPALRDEILAQLANQVWRNPNAYNSKRGWLLLAACLSGFAPSPHLDKFLLKFVSDYGQNGFQAVCQHRLLQAMG------SGAARTFPPTQLEWTAIQEKASMALDVSCFNGDQFSCPVHTWSTGEAVAGDILKHRGLADGWRGWTVAMKNGVQWAELAGHDYVLDLVSDLELLRDFPRQKSYFIVGAEGPLAGRGDTRGVFGNCWDSDEDTPTRPQPQDHVAKMPDLDGYCSHKEDGTNGETEAQRWTSNRQAVDSIGESTVPPRELDGYLDSLFDPVLACGDADLEKPTAIAYRMKGGGQPGGGGGSTSEDTSRRPPEPKLKPIPGLDASTLALQQAFIHRQAVLLAREMTLQALALQQQPLSATSRPQLPERPLAPEARPKTVVGTGPPAKPVLVRPTPQSWAPGSVAKAPKIPSKP---VAVPILAQDWTAPESISASPELVRYSTLNSEHFPQPTQQIRSIIKQYKQPPWAGHPEARRTDGGKVFRRPPDPHEEALMILKGQKTQLAVVPGTQVSREAVAMVKPVTSAPRPCMGPTPVQPSRSLEPPEDPVQTQLHRLVNPN-FYGYQDIPWRIFLRKEVFYPKDNYSHPVQLDLLFRQILHDTFSEACLRISEDERLQMKALFAQNQLDTQRPLVTESVKRAAISMARDSWEIYFSRLFPAMGSVGTGVQILAVSHTGIKLLQMVKGSKEASRRLRVLCAYSFADILFVTMPSQNMLEFNLSNEKLILFSARAQQVKTLVDTFILELKKDSDYVVAVRNFLSEDPELLSFHKGDIIHLQSLEPTRVGYSAGCVVRKKLVYLEELRRRGPDFGWRFGAVHGRVGRFPSELVQPAAAPDFLQLPAEPGRGRAAAVAAAVASAAAAQEVGRRREGPPVRARSADSGEDSIALPPSTMLEFAQKYFRDPRRRPRDGLKLKSKEDRESKTLEDVLCFTKVPIQESLIELSDSNLNKMAVDMFVAVMRFMGDAPLK-GQSELDVLCTLLKLCGDHEVMRDECYCQIVKQITDNSSPKQDSCQRGWRLLYIMAAYYSCSEVFYPYLIRFLQHVSWTPGLPFQGIAKACEQNLQKTLRFGGRLEFPSNMELRAMLAGRSSKRQLFLLPGGLERHLKIKTCTVALDVIEGLCTEMALTRPEAFDEYVIFVVTNRGQHVCPLSCRAYILDVASEMEQVDGGYTLWFRRVLWDQPLKFEN---ELYVTMHYNQVLPDYLKGLFSSVPAR-QPTEQQLQQVSKLASLQHRAKDHFYLPSVREVQEYIPAQLY--HTTAGDTWLNLVSQHRQQTQALSPHQARAQFLGLLSAFPLFGSSFFFIQSCSN----------VLVPAPCILAVNHNGLNFLSTKTHELIVKIPLKEIQSTWTQQPTANSSYPYVEISLGDVAAQRTMQLQLEQGLELCRVVAVHVESMLSAREERLTLPPSEITLL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UKN7-1", "uniprot_id": "MYO15_HUMAN", "id": "Q9UKN7-1", "name": "Unconventional myosin-XV", "aln": "MAKEEDEEKKAKKGKKGKKAPEPEKPKRSLKGTSRLFMGFRDRTPKISKKGQFRSASAFFWGLHTGPQKTKRKRKARTVLKSTSKLMTQMRMGKKKRAMKGKKPSFMVIRFPGRRGYGRLRPRARSLSKASTAINWLTKKFLLKKAEESGSEQATVDAWLQRSSSRMGSRKLPFPSGAEILRPGGRLRRFPRSRSIYASGEPLGFLPFEDEAPFHHSGSRKSLYGLEGFQDLGEYYDYHRDGDDYYDRQSLHRYEEQEPYLAGLGPYSPAWPPYGDHYYGYPPEDPYDYYHPDYYGGPFDPGYTYGYGY--DDYEPPYAPPSGYSSPYSYHDGYEGEAHPYGYYLDPYAPYDAPYPPYDLPYHTPYDVPYFDPYGVHYTVPYAEGVYGGGDEAIYPPEVPYFYPEESASAFVYPWVPPPIPSPHNPYAHAMDDIAELEEPEDAGVERQGTSFRLPSAAFFEQQGMDKPARSKLSLIRKFRLFPRPQVKLFGKEKLEVPLPPSLDIPLPLGDADEEEDEEELPPVSAVPYGHPFWGFLTPRQRNLQRALSAFGAHRGLG-FGPEFGRPVPRPATSLARFLKKTLSEKKPIARLRGSQKARAGGPAVREAAYKRFGYKLAGMDPEKPGTPIVLRRAQPRARSSNDARRPPAPQPAPRTLSHWSALLSPPVPPRPPSSGPPPAPPLSPALSGLPRPAS----PYGSLRRHPPPWAAPAHVPPAPQASWWAFVEPPAVSPEVPPDLLAFPGPRPSFRGSRRRG--AAFGFPGASPRASRRRAWSPLASPQPSLRSSPGLGYCSPLAPPSPQLSLRTGPFQPPFLPPARRPRSLQESPAPRRAAGRLGPPGSPLPGSPRPPSPPLGLCHSPRRSSLNLPSRLPHTWRRLSEPPTRAVKPQVRLPFHRPPRAGAWRAP---LEHRESPREPEDSETPWTVPPLAPSWDVDMPPTQRPPSPWPGGAGSRRGFSRPPPVPENPFLQLLGPVPSPTLQPEDPAADMTRVFLGRHHEPGPGQLTKSAGPTPEKPEEEATLGDPQLPAETKPPTPAPPKDVTPPKDITPPKDVLPEQKTLRPSLSYPLAACDQTRATWPPWHRWGTLPQAAAPLAPIRAPEPLPKGGERRQAAPGRFAVVMPRVQKLSSFQRVGPATLKPQVQPIQDPK----PRACSLRWSCLWLRADAYGPWPRVHTHPQSCHLG-PGAACLSLRGSWEEVGPPSWRNKMHSIRNLPSMRFREQHGEDGVEDMTQLEDLQETTVLSNLKIRFERNLIYTYIGSILVSVNPYQMFGIYGPEQVQQYNGRALGENPPHLFAVANLAFAKMLDAKQNQCIIISGESGSGKTEATKLILRYLAAMNQKREVMQQIKILEATPLLESFGNAKTVRNDNSSRFGKFVEIFLEGGVISGAITSQYLLEKSRIVFQAKNERNYHIFYELLAGLPAQLRQAFSLQEAETYYYLNQGGNCEIAGKSDADDFRRLLAAMEVLGFSSEDQDSIFRILASILHLGNVYFEKYETDAQEVASVVSAREIQAVAELLQISPEGLQKAITFKVTETMREKIFTPLTVESAVDARDAIAKVLYALLFSWLITRVNALVSPRQDTLSIAILDIYGFEDLSFNSFEQLCINYANENLQYLFNKIVFQEEQEEYIREQIDWQEITFADNQPCINLISLKPYGILRILDDQCCFPQATDHTFLQKCHYHHGANPLYSKPKMP-LPEFTIKHYAGKVTYQVHKFLDKNHDQVRQDVLDLFVRSRTRVVAHLFSSHAPQAAPQRLGKSSSVTRLYKAHTVAAKFQQSLLDLVEKMERCNPLFMRCLKPNHKKEPGLFEPDVVMAQLRYSGVLETVRIRKEGFPVRLPFQGFIDRYCCLVALKHDLPANGDMCVSVLSRLCKVMPNMYRVGVSKLFLKEHLYQLLESMREHVLNLAALTLQRCLRGFFIKRRFRSLRHKIILLQSRARGYLARQRYQQMRRSLVKFRSLVHAYVSRRRYLKLRAEWRCQVEGALLWEQEELSKREVVAVGHLEVPAELAGLLQAVAGLGLAQVPQVAPVRTPRLQAEPRVTLPLDINNYPMAKFVQCHFKEPAFGMLTVPLRTPLTQLPAEHHAEAVSIFKLILRFMGDPHLHGARENIFGNYIVQKGLAVPELRDEILAQLANQVWHNHNAHNAERGWLLLAACLSGFAPSPCFNKYLLKFVSDYGRNGFQAVCQHRLMQAMGRAQQQGSGAARTLPPTQLEWTATYEKASMALDVGCFNGDQFSCPVHSWSTGEEVAGDILRHRGLADGWRGWTVAMKNGVQWAELAGHDYVLDLVSDLELLRDFPRQKSYFIVGTEGPAASRGGPKVVFGNSWDSDEDMSTRPQPQEHMPKVLDSDGYSSHNQDGTNGETEAQRGTATHQESDSLGEPAVPHKGLDCYLDSLFDPVLSYGDADLEKPTAIAYRMKGGGQPGGGSSSGTEDTPRRPPEP--KPIPGLDASTLALQQAFIHKQAVLLAREMTLQATALQQQPLSAALRSLPAEKPPAPEAQPTSVG-TGPPAKPVLLRATPKPLAPAPLAKAPRLPIKP---VAAPVLAQDQASPETTSPSPELVRYSTLNSEHFPQPTQQIKNIVRQYQQPFRGGRPEALRKDGGKVFMKRPDPHEEALMILKGQMTHLAAAPGTQVSREAVALVKPVTSAPRPSMAPTSALPSRSLEPPEELTQTRLHRLINPN-FYGYQDAPWKIFLRKEVFYPKDSYSHPVQLDLLFRQILHDTLSEACLRISEDERLRMKALFAQNQLDTQKPLVTESVKRAVVSTARDTWEVYFSRIFPATGSVGTGVQLLAVSHVGIKLLRMVKGGQEAGGQLRVLRAYSFADILFVTMPSQNMLEFNLASEKVILFSARAHQVKTLVDDFILELKKDSDYVVAVRNFLPEDPALLAFHKGDIIHLQPLEPPRVGYSAGCVVRRKVVYLEELRRRGPDFGWRFGTIHGRVGRFPSELVQPAAAPDFLQLPTEPGRGRAAAVAAAVASAAAAQEVGRRREGPPVRARSADHGEDALALPPYTMLEFAQKYFRDPQRRPQDGLRLKSKEPRESRTLEDMLCFTKTPLQESLIELSDSSLSKMATDMFLAVMRFMGDAPLK-GQSDLDVLCNLLKLCGDHEVMRDECYCQVVKQITDNTSSKQDSCQRGWRLLYIVTAYHSCSEVLHPHLTRFLQDVSRTPGLPFQGIAKACEQNLQKTLRFGGRLELPSSIELRAMLAGRSSKRQLFLLPGGLERHLKIKTCTVALDVVEEICAEMALTRPEAFNEYVIFVVTNRGQHVCPLSRRAYILDVASEMEQVDGGYMLWFRRVLWDQPLKFEN---ELYVTMHYNQVLPDYLKGLFSSVPAS-RPSEQLLQQVSKLASLQHRAKDHFYLPSVREVQEYIPAQLY--RTTAGSTWLNLVSQHRQQTQALSPHQARAQFLGLLSALPMFGSSFFFIQSCSN----------IAVPAPCILAINHNGLNFLSTETHELMVKFPLKEIQSTRTQRPTANSSYPYVEIALGDVAAQRTLQLQLEQGLELCRVVAVHVENLLSAHEKRLTLPPSEITLL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q0KHU0-1", "uniprot_id": "Q0KHU0_DROME", "id": "Q0KHU0-1", "name": "", "aln": "-------------------------------------MDWAEGDLVWFDPGMG----------HPIPGEIQEVHRAAQVIVVQALIKGKMRIVR------------FHLEPWQRGGGGSVTPSPAQSPSLALLSPHVLRRQRPASLEDFEDLPNLSAKHPALPSSRLRRLKCRYPQVVKRLS-------TLCSDVIARHPQTFALQPGEGSLRARQDLGSSGVEDMTLLDDLHEASLLWN-LRLRYDKGLIYTFAGSILIAVNP--------------YKMFPDAYGLEVAKQYAGRPLGSLPPHLFAIGAAAHAALPSPQVVVISGESGSGKTESTKLVMQYLAAVVPGGGS--ASAVITEQILEAAPLLEAFG------NARTARNDNSSRFGKYLEVYFKSGAIVGAKITQYLLEKSRIVTQAPGERNYHVFYELLGGLSETERSKYGLLEADKYFYLNQGATDCASGRVDWESLQGAMQVLGVSEGEREGIVRVLAAVLHLGNVYFHRRQLRHGQEGVEVGSDAEIKWAAHLLHISADGLHRALTSRTTEARAERLHTPLGIDQALDARDAFAKALYAGLFNWLVSRINSIVQKGGTHDAHRISILDIFGFEDLAEN-SFEQLCINYANENLQLYFNKHVFKLEQAEYARERLEWTPLAWDDNLPVIHLLAKKPVG--------------------ICHLLDDESNFPRATDLSFLEKCHYNHALSELYARPRIGAQEFGVTHYAG-------QVWYCVDGFLDKNRDALRGDVLELLASSRLPLVG-------------ELTKQLRAQRDAGKTLPKGSNGRFVTMKPRTPTVAARFADSLQQLLQSMGRCHPWFVRCIKPNQEKHALRMDMPCVLQQLRYLGMLDTIQIRQRGYPVRLRFQHFVERYRHLLPSPLARGTPYRELCRALLEAMPRTGVEGPDYQLG-----------------------------------------ATRVFLREALHRALESGRTERLRRAAVSVQRHVR---------------------------------GMLVRRQLARRQAAATRLQARWRGQRAQQRYERLRKGALTAQRLWRGRQAR---RRVQQLRSDHRRRQEAREAAQRAREAREAKQAVLERSQLSYLDIP-----AELAFIYSKLQGWSPPHGDRHLVKVLG------TVPGPPSSAVQLPEDLGQFSFGKFSSVYCNGLRLQPRREPITAPLLTRAASRDQDFQDALAVFKLILRWSNDKALEGAKEKLLADYIVHKALSSRGLRDEILVQLCNQVHGLPPNSGEATRLWQLLGQCLCCFQPSAAFS------KYLMRFVDDEAP-----ESLRPLLLRQLLRQQGGGTSSGAVGAGACRSFVPAWLEWRAWTRGCDMALPLTLPDEASQTVAVDSWTSCEEAAA------LAVSSLGVASRGWTLVLDDGQQLTDSCGLDYVMDLIAEKELCPAFPAPRSDLLRSGAKFART--TLPDAVKRPAVPPPAPPTSSGKEDVPRERRSSRELLSRSSALNERYFEREPSPGPGQGSSTGQAKSRSKSLDDLLAGDIVPVPTDCDSQEPLHTLGLSESRLN----DRYHSAERLAP--------------VGKDTGPRYQKSQHAGRRSHAASHG-------------------------SHSSKYADKAEYATRSSAMSDTSEAPSLASHVRRVRVPSQASDVDQFLDDLFSPVLDGSLDELSDARS--LAASIRGGSYEQENEAESEIDDLDDYINDIFQPIPLVQNLEKLTSKDQ---------LAAIIKGGGVASKPEERDEESEIEDLDDYINELFEPIPVAEGLDKLTSKEHLAVSIRGGGSTDSNGADPLLHQLMQLPGETESG-----------PALYQQQVQRAFLQSAMAQN-----LQIQQQLLAQNQALQTLLSQQAAAAAANNSTSPPPAPPILSSLSISPPPPQSPMRMKATRSSLVVMESLQPPPPPPPPPMPPPLECKDPSETRHFLDPYG---RAKTVRIGKWRWPPPQDEPQFQTEEDFFAFKMRQHQRKTTPQAQHHQMTSNGGMMESGPGARGASATAIEWEEFEIESPTPPPMSGQLMRSS----------IRLETTTTTTTSAVNNRDRDRETQDVGQPMQSVVTTKLAKKSFEIGADRPPPGSVGKLKLSSEMRQRLEQVTAG---------HSVRSTVSTKSEQRAPAKLEDTRKLMLQQQLGGLFASVSGGNSGPGGVVDSHATVRTQIERMEGKLSPPPAPPSGGWPGVLLPPAPSVPAPPPPIRPPSMAPPAPPPAPQ--SPPTARSPEPEPDYRTSSSQVVKEHVPAFIQ------RQERDTFGAVRQQQMISSHHLHLEDHSASSSPAVAAWEQAERERSRSRSRSRDREDYSESVWDRAEVEGPASGSGSEKEREKRERERERLYEIRQVERERESHKVYQPAPPRVIQASMDTTGGHRREDRTGGLATFRTHMAQKYEHERKRKSSASSGMREELDSMHMTTPPPVIVPAPVPPPSSTSPGLGVVSGVLMGSGSGGSTACLTYNRVPWKLRVRKEVFQPHEPIG-------------PPVALDLLFAQVLGDVFGVTPCLRITPQEKSSALNMLHGHGVSVDTLSNRNGSGAGGGGNGGQVRALVKRHLVDMARDWPLYFARLFAVQGAPLYPDVSIMGVSHSGLYLARRDADYLIVVQAISFGEIQSAVTLPRP------------AALQLNLRNGKHLALHAARAAAIQSMVTTFVQEFRKSQSKASTLSSGARAAAQTLN-VPLERLESRQAHAQRNEHGVDGGSRQNEQLQQSELHHHLQQQQQQQQQQQHHQQQQQQQQLEDAMEEQHMATDHQQQQQQQLGQQQGQQQRFLK-----------------------------------------------------QQSYLHSARKSNAGQQPSSLTNGQVHHQEQMLQQQQQQSQSLPHHDLDANYLQDESNGGTPPSVTKYSLLQFAMQHFRNDQLRDADRHHER-HQSAANRSYAELVKWQGHAIRLPLLRLPN-DLAPLALECFDCILRYCGDIPLDPDLTEVKCVYTVLMHCHKYLALRDEVYCQLMKQTTANRSPCPDSSQRAWRLLSILAAYFGCSDALRPYLMEHLTSAASDRRRSCHGTAAVCLTNLRKTARCGGRKNVPSVEEVTAVSAGRSARRQIYRLPGGAERVVNTRCSTVVADVIAELCALLGVESEAEQQEFSLYCIVQGDAFTMPLAADEYILDVTTELLKSGQPFYLIFCRSVWHFALKREPAPMPLYVEVLFNQVAPDYLEGLLLELPGNGVPVPEMVRDMARIAALLHRAADLSHVPAMKEIKFLLPKPALGIREIRPAQWVGLVQSAWPQVANLSPGQVKAQFLNVLATWPLFGSSFFAVKRIWAEEGPHVEDNHSPMWRDLILALNRRGVLFLDPNTHETLQHWSFMEVISTRKVR--SEDGALFLDMKVGNLMQQRVIRVQTEQAHEISRLVRQYITMAQISQRDKRELN-------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.: : . * *. * : :. ::* *: : : :**: : : :. * * * : * . . .. : : :: . *: . .***: * :*. .: * * * :...: * *.. :: . ..: .: ::** * . **: :: : . . * . :* * .: . : :. . :* * * . *. * . .. :. . * ::.:* *. ... . : *. . * : :: :. .. .: **. .: .. *: :** . * .::. : *. :* : *.. *.: . .. :* * : . : :* .*:***:: :. : . :* . * . : : :.*:.. : . . * : . **:: . : . * . : : .:. .. * . * . . :* . * * . . :. .:.:. :. : . . *.: .: :... : .. ** . . * *.*.: .* . . .** * . : : .:.*:. . . : * * *.: . * :* . ::* . : : : * * . * :: * .*: . * . : * : :.* : : * : :. . :: .: . * : : * : : : : :.* . . :. * * . : :: : * . .: . : * :: . * :: :. * : .: ::. . :. *: : * :: *.: : : .* : .*: :* :. . : *: : * :. ... ::: * :: * . :. * * * : .. : * * ::* : :.:: * **. *...: .:. .** :** . . * . . *: .: * * . ** *. : * ... :::.... * . *:* *: . :..::* *.: : . : : * .: :: : *.. : * * *.:: ::: ** * .*: :*:. .: * . : . .:. . .**.:: : ::* *:*. * :: .* :.* :. *.: : . .: :*..* :..: ..: * *.... : . . : :*.:***. .. * :. ** : :*: :* : . : : .: ..: : . : *.* .*..* : * . * :*: : . ..: : :. * :** :: : .: *::: . .::.: . .:* :* : : * :. ::. :*:: : : :::: : .: : * *: . * :. . : : ** : : ::::* . * . : . . : *:* :*:. . :. ::. * * * ** . *: : * :. : :. . :* : .. : : :: : * . : . *. : : :: : . . * : :. : :* .. .. *: :.: ::** *. . ::. .* : *.: : :*:. . . * *: .*.:: :. . . . . .* ** : * : . : : * . .. . . :.* .: ::*:. . : ::: .* * . *: :.:: . ..: . . . . * *. : .: *.. * .* *. . * :: . : : *: * * . :::. . : : * : .: :* : :: *. . . . . .* . .* *. :* . :. .: . : : * :. :.. ** : * * * .:*: . : : : : * * ** :::: : :. . . . .* * : **. : * * . . :. :: .: . .: : :: : ::.:.: . * :* . : *. .:.: *.:. :: * : . .::.:*.: * : : * :: . .* . : : . * : : :: *: : .:: . : :* : * * : : .. ::: :: * * .. ::.* .: * *:. .*:. : . : ::: . :. . * . ::. ::*:** ::**: : * * : : :: .:: ::: : .:: .*:.*.: .* :* : * .::*: ** **. . .::. : .:* * .: .:*** ***::** * * *. **.**.**** *::**..**:.: *:* ..* .: . :* * .* **:** * *** :.** *: *: ****::**:: **** ** :: : .**. **: :*: :.: :*: :: :.: . .. **: *****:: : : . : * * * :*. .** * *** : :*** ****:**: .:*. * : :::::::*:* *** * ::*:::*:: :* : *:.**.. *. *** *.:****.:*:: *:****** :: : ***:*:.*: **..:*** : : .: *: ** . : ::.. :::: :*:: **.:::* **. *:.*:* :: ::..: * ", "identical_positions": 447, "similar_positions": 1022, "identity": "12.51%" }, { "cls_id": "homologset.agr.MGI:1261813", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3YWE6-1", "uniprot_id": "MN1_MOUSE", "id": "D3YWE6-1", "name": "Transcriptional activator MN1", "aln": "MFGLDQFEPQINSRHAGQGEGNFNEAGLSMNAHFKAPAFHAGPPTGPVDPAISALGEPPILGLNM-----EPYGFHARSHSELHAGGLQAQP-VHGFFGGQQPHHSHPGGHHPHQHHPHFGGNFGGPDPGASCLHGGRLLGYGGAAGGLGSQPPFAESY-EHMAESQGPEG-FGPQ--RPGNLPDFHSSG--TSGHAVPAPCLPLDQSPNRAASFHGLSASSGS-DSHSLEPRRVTNQGAVDSLEYNYPSEPPSGHFDM--FSPSDS-EGQLPHYAAGRQVPGGAFPGASAMPRASGMVGLSKMHSQPPQPPPQQQQP------QHGVFFERFGGARKMPVGLEPAVGSRHPLMQPPQQAPPPPQQPPPQQ----QPPPP-GLLVRQNSCPPALPRPQQG-EAGTPSGGLQDGGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFSMQH--PPPQQAPNQRLQHFDAPPYMNVAKRPRFDFP-GSAGVDRCASWNGSMHNG-TLDNQLSPSAYPGLPGEFTPPVPDSFSSGPPLQHPGPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQ----RQNAALMIKQMASRNQQQRLRQPNLAQLGHPGDVGQGGLVHGGSVGGLAQTNFEREGGSAGAGRLSGFEQQAPHLAQESAWFPGPHPP-GDLLPRRMGGAGLPTDCGPHDPALAPPPAPGGSGVLFRGSLQEPLRMPGEGHVPALASP--GLQFGGSLAGLGQLQSPGAGVGLPNAPSERRPPPPDFPAPALGGQPGFPFGSGSRQATPHS-APGVNSPPSAGSGS--SGAGGG--AYPPQPDFQPSQRNSASKLGALSLGSFNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNEPDS----AVAAGNPGSDYFPGGTTPGAPGPGGPSGTSGGGSKASGPPNPPIQGDSTSLSPNYTLESTSGNDGKPVPGGSGRGRGRRKRDSGHVSPGTFFDKYSTAPDSGGAPGVSPGQQQAPGSAAGGSSVNEARG-PTPHEKALTSPSWGKGAELLLGDQPDLMASLDSTAKSDGSSPHVG---EFASDEVSTSYANEDEVSSSSDNTTALAKASRSPLVTSSPKLPPRGVGAGEHTPKAS--ALGLGILSTSTSTPDSYGGGVGTGHPGTPGLEQVRTPTSSSGAQPPDEIHPLEILQAQIQLQRQQFSISEDQPLGLKGSKKAECAVGASGAQNGDSELGSCCSEAVKSAMSTIDLDSLMAEHSTTWYMPPDKALVDGGDEDKTLAPWEKAKSQNPNNKEAHDHPTNKAS--------ATQPGSHLQCLTVHCTD--GDPKAR-TSVPTWRSLHSDISNRFGTFVAALT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4AAP6-1", "uniprot_id": "D4AAP6_RAT", "id": "D4AAP6-1", "name": "", "aln": "MFGLDQFEPQINSRHAGQGEGNFNEAGLSMNAHFKAPAFHAGPPPGPVDPAISALGEPPILGLNM-----EPYGFHARGHSELHAGGLQAQP-VHGFFGGQQPHHSHPGGHHPHQHHPHFGGNFGGPDPGASCLHGGRLLGYGGAASGLGSQPPFAESY-EHMAESQGPEG-FGPQ--RPGNLPDFHSSG--TSGHAVPAPCLPLDQSPNRAASFHGLSASSGS-DSHSLEPRRVTNQGAVDSLEYNYPSEPPSGHFDM--FSPSDS-EGQLPHYAAGRQVPGGAFPGASAMPRASGMVGLSKMHGQPPQPPPPQQQP------QHGVFFERFGGARKMPVGLEPAVGSRHPLMQPPQQAPPPPQQQPQQQ----QPPPPPGLLVRQNSCPPALPRPQQG-EAGTPSGGLQDGGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFSMQH--PPPQQAPNQRLQHFDAPPYMNVAKRPRFDFP-GSTGVDRCASWNGSMHNG-TLDNQLSPSAYPGLPGEFTPPVPDSFPSGPPLQHPGPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQHQRLRQPNLAQLGHPGDVGQGGLVHGGSVSGLAQTNFEREGGSTGAGRLGGFEQQAPHLAQESAWFPGPHPP-GDLLPRRMGSAGLPADCGPHDPGLAPPPAPGGSGVLFRGSLQEPLRMPGEGHVPALASP--GLQFGSSLAGLGQLQSPGAGVGLPNAPSERRPPPPDFPAPALGGQPGFPFGSGSRQATPHS-APGVNSPPSAGAGSGSSGAAGG--AYPPQPDFQSSQRNSASKLGALSLGSFNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNEPDS----AVAAGNPGSDYFPGGTTPGAPGPGGPSGTSGGGSKASGPPNPPIQGDSTSLSPNYTLESTSGSDGKPVPGGSGRGRGRRKRDSGHVSPGTFFDKYSAAPDSGGAPGVSPGQQQAPGSAAGGSSVNEARG-PTPHEKALTSPSWGKGAELLLGDQPDLMASLDSTAKSDGSSPHVG---EFASDEVSTSYANEDEVSSSSDNTTALAKASRSPLVTSSPKLPPRGVGAGEHTPKAS--ALGLGILSTSTSTPDSYGGGVGTGHPGTPGLEQVRTPTSSSGAPPPDEIHPLEILQAQIQLQRQQFSISEDQPLGLKGSKKTECAVGASGAQNGDSELGSCCSEAVKSAMSTIDLDSLMAEHSTTWYMPPDKALVDGGDDDKTLAPWEKAKSQNPNNKEVHDHPTNKAS--------ATQPGSHLQCLTVHCTD--GDPKAR-TSVPTWRSLHSDISNRFGTFVAALT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q10571-1", "uniprot_id": "MN1_HUMAN", "id": "Q10571-1", "name": "Transcriptional activator MN1", "aln": "MFGLDQFEPQVNSRNAGQGERNFNETGLSMNTHFKAPAFHTGGPPGPVDPAMSALGEPPILGMNM-----EPYGFHARGHSELHAGGLQAQP-VHGFFGGQQPHHGHPGSHHPHQHHPHFGGNFGGPDPGASCLHGGRLLGYGGAAGGLGSQPPFAEGY-EHMAESQGPES-FGPQ--RPGNLPDFHSSG--ASSHAVPAPCLPLDQSPNRAASFHGLPSSSGS-DSHSLEPRRVTNQGAVDSLEYNYPGEAPSGHFDM--FSPSDS-EGQLPHYAAGRQVPGGAFPGASAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERFSGARKMPVGLEPSVGSRHPLMQPPQQAPPPPQQQPPQQPPQQQPPPPPGLLVRQNSCPPALPRPQQG-EAGTPSGGLQDGGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFSMQH--PPPQQAPNQRLQHFDAPPYMNVAKRPRFDFP-GSAGVDRCASWNGSMHNG-ALDNHLSPSAYPGLPGEFTPPVPDSFPSGPPLQHPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQ--QRQNAALMIKQMASRNQQQRLRQPNLAQLGHPGDVGQGGLVHGGPVGGLAQPNFEREGGSTGAGRLGTFEQQAPHLAQESAWFSGPHPPPGDLLPRRMGGSGLPADCGPHDPSLAPPPPPGGSGVLFRGPLQEPMRMPGEGHVPALPSP--GLQFGGSLGGLGQLQSPGAGVGLPSAASERRPPPPDFATSALGGQPGFPFGAAGRQSTPHS-GPGVNSPPSAGGGGGSSGGGGGGGAYPPQPDFQPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETDG----AAVAGNPGSDYFPGGTAPGAPGPGGPSGTSSSGSKASGPPNPPAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSPGTFFDKYSAAPDSGGAPGVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGDQPDLIGSLDGGAKSDSSSPNVG---EFASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSPKLPPRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSSGAPPPDEIHPLEILQAQIQLQRQQFSISEDQPLGLKGGKKGECAVGASGAQNGDSELGSCCSEAVKSAMSTIDLDSLMAEHSAAWYMPADKALVDSADDDKTLAPWEKAKPQNPNSKEAHDLPANKAS--------ASQPGSHLQCLSVHCTDDVGDAKAR-ASVPTWRSLHSDISNRFGTFVAALT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B8JKI7-1", "uniprot_id": "B8JKI7_DANRE", "id": "B8JKI7-1", "name": "", "aln": "MFELEQFGPQINNRNFGHTEKNFNKPKVSMNSHYKSPGFHTGGSQNTAEPGMGPLNETPVIEMNINMSRGEQYGGFQRGHSELHTGNLQQQPSMHGFFNPQQPHN-HSHGHQTHPHQ-HFGGNFG-PEPGSSCLHSGRVMGYN---SSMGLQQGFTEGF-DSLSEGQSADGGFSQQQQRTSSMSDFQHHGPPSGNHPVPAPCLPLDQSPNRAASFHGLSSSSSSSESHNLEPRRMPPPAAVEGLDYSFPNEPSSRHFDVPVYSPSES-DSQLSHFGTGRQVPGSNFPGNTGLSRAPGMQGIAKEH---PHAPPQQQQPS----AQHSVFFERFGGGRKIPVGIEP--GARHPLMQ--QQQP--------------------GLIGRQNTCPPSLPQPPLS-ETASANVGMQEGGVMMPGQHNQFEYPIHRPENRRIHSYGDPIFNMQQQPPPPQQPPNQRLQHFDSP-YLNMGKRPRFDFPNATHGRESCGSWNSAMEN------NLSPAAYPGLPGEFTPPVTDGFSTGPSLQLTGSEQQSMQQQQ----------------------------NAAMMIKQMASRSQQQRMRQPSLQQLGHHNDVSQGPLGPGGPVGGMPQSSFERENG----GRMVNFDGRSPHMTMESGWFPGPHPP-GEMLGHRMGSSG---EMGDRDIQQNGPGMMFRAGVSGMG-MQESMRVPGEGHVQPLLSPNIHSQFNSGMGSLSQMQSPSAGVGLPNTPSERRS--NDFPGPPMGGPSQFQYGGSNRQGASHGNSQGVNTSPGS---------------FTCQSDFPTSQRSSVSKLGGLSLGNFSKTNGKDNVFGQSCLAALSTACQNMIASLGAPNLNVTFNKKTQAEGKRKLSQTEQDLNNSAVNGTGNTGTEYFPSLTAP-QNGQMPPAGNSNAKPLSQ---NQTVQGEASALSPNFNMDTTPCSEGKAATG-SGRGRGRRKRDSGHVSPGIFF------PSENSNPVVSPSQQ--------VSSAERSTG--TPHEKPHTSPSWGKGGDLLLGDQSDLMSSLDSGIQSASKSEVCSPRMDFTDDAVVTHYSNEDEVSSSSD-AQSSVKPGCSPLLG-SPKMP-NGLMSGQK---------GQGLSNQTTSTSDGFG---GAGHPGTPGMEQVRTPSSTSGQ---DEIHPLEILQAQIQLQRQQFSISEDQPLAVNNNKKS--------SELGDGELASCGPDAEKSSVGTIDLDTLMAEQHATWYVPSDKCLLEDSEEEK--STWEKNKAQAT-IKEEADLTQNKSGGGAGSSGTAGGMGSHLQCLSVHCTDELGESKGRGGPVPSWRSLHSDISNRFGTFVAALT", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0ACD6B6L5-1", "uniprot_id": "A0ACD6B6L5_DANRE", "id": "A0ACD6B6L5-1", "name": "", "aln": "-----------------------------MNSNYNSAGFHMKGPSVAVEPMMGPLNESPMQGLNFVSNR-DQYGFQTHGHGDMLGMGVQPQH----QLHMQGPFNHQPPNHDQHSHL--------YQDSVPSCLHGDRHMGFS--STNAGHPHMFEGGFSQQLAEPQSRECISQQQQQRMAAMPEFQPHGHPNGNHAVPAPCLPLDQSPNRAASFHGLPSSSPE--THRLEHYRLFPQGRMGGSEHCFPCDPLTGNFDMTGFSTADSSEHKLPYCETGNQVVGGNFSTCNRSGSRGPMMGSSKVD---------QQLP------QQNVFSDRFGNRGKM----DPGVNTRHHLMA--QQRP--------------------GPVVRQNPGSPALPRFYHTPDFVANNTDVQGGGPMVHVQHGHLDRPIHRLNNHNMHPFGEPVFDVPQLAPQPP-------HHLSSLPYLNMAKRPRFDLPNGSAG-ESCSPLSHSLHNRPSLENHLSPSAFPSPMGDFTSHVTDGFPSGPLPLSSGPQQQQQQQQR--------------------------RQNAAMMIKQMASRSQQQRMRQPDLQQLNLHGDVTSNGMVCRGPLGSVSQSNFEKKHN-----FHGNFD--SPHLPQENSWFPEPQQHCRETNTHAL------------EQAENGHNIIFRPSVTSMD--MQSLNSPGAHHP-----------FENNVSNPLQMQSPDESNMQSGAPTDRRP--AEFGGMVMRRQHSFPPGGPSQQGAPQSNPPGFSSSPGN---------------YPAHPEYLSSQHLSVNKLGALSLGNLNKASTKDSVFGQSCLAALSTACQNMIASLGAPNLNVTFNKKSQNEAKRKAGQVEQDIN---SSGSSGPGAEYFQSNASQ--NSQTPCSGNNNNTMVGQSGTGQMVKREASTLSPNDSMES--GCEGKMATG-NGKGRGKKRRDSGHISPGNFS------PPSGGNPVVSPGQQ-----GSNLSMGMESRG--KTPERTLVSPSFGK---------PDLATSMDSGIQSVGKSDGVSPCMDYLDDASPN-YSTED------------PRPCR------------------------------AGVKCNSENR---------ASYADASCMEQVRTPLSNTGQ---DEVHPLEILQAQIQLQRQQFSISEDQPMGGKTSKKADCQ----ASLNGECTLANSSPVTGKSSVNTIDLDSLMTEQHATWYVPGNKALIEDPSNDKCLGYWERARGQSD-NKEGHG------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **:::::..** . ..:* :..*.*.*: :*: : ** :.*.:: .:* * : * *.: :. .*. * * :. .****..* :*:. . * * .: : ::* *. : * * . :.:*: * ..*.*********************.:** . :* ** *: . : . :: :* :. : :**: :*.::* : :*.: :*.** *. *. . * * :* . ** *:.** :**.. *: :* .:** ** ** * * : ***. .*:**: : : . .:* ** *: ** ::: **** :*: :*.:.:*:*.: : * * :*:.: *:*:.******:* .: * : *.. . ::.* :***:*:*. *:**. *.*.*.:** ...::*. ***: ***:********.*:**:***.* **. .** .. : *.:..:.*..**:: . *: :**:. *..**. *: : : : : ..* . :.:. ** * * ..:.. *:***. . ..:.::**. :* : * *. .:*.:.:. *..:.*. :. :.:: .**: *..***.****.:.*.. **.:********************************. *.*** .* * * :...*::** . :: . :*... .. . : :.::**** .::: :** ..* .*:***:::*****:*** * * ... * ***.** * .: * .. *:. .***:** .** *:*. :* ..* . :: .* . *:.** :. *: : . ..:..:. :****** *.:* **:************************:. : .** : *: *... . : **::.*****:**:*: ::**:* :*.*::. .::* . **: : * ** . ", "identical_positions": 355, "similar_positions": 356, "identity": "26.06%" }, { "cls_id": "homologset.agr.MGI:1261814", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q920Q0-1", "uniprot_id": "PALM_RAT", "id": "Q920Q0-1", "name": "Paralemmin-1", "aln": "MEVLATDTVSQQERLQAIAEKRRKQAEIESKRRQLEDDRRQLQYLKSKALRERWLLEGTPSSASEGDEDMRKQMQEDEQKARSLEESITRLEKEIDVLEFGESAPAAPKENSAAPSPIRPHSTSPAKEEQKSETMVNAQQTPLGTPKENRKS-TPVRSPGGSTMMKAAMYSVEITVEKDKVTGETRVLSSTTLLPRDPLPQGVKVYEDETKVVHAV---DGLSENGIQPLSSSEVDELIHKADEVTLSEAGSTTGPAEPRGLAEDVTR----TTPSRR------EITGVEAQPGEATSGPPGIQPGQEPPVTMVFMGYQNVEDEAETKKVLGLQDT-IKAELVVIED-------SVTPREPAPLNGSAAELP---ATKEENQTGPTTTPSDTQDLDMK-KPRCRCCSVM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z0P4-1", "uniprot_id": "PALM_MOUSE", "id": "Q9Z0P4-1", "name": "Paralemmin-1", "aln": "MEVLATDTASQQERLQAIAEKRRKQAEIESKRRQLEDDRRQLQYLKSKALRERWLLEGTPSSASEGDEDMRKQMQEDEQKARGLEESITRLEKEIDVLEFGESAPAASKENSAAPSPGRPQSASPAKEEQKSETLVNAQQTPLGTPKENRTS-TPVRSPGGSTMMKAAMYSVEITVEKDKVTGETRVLSSTTVLPRDPLPQGVKVYEDETKVVHAV---DGIAENGIQPLSSSEVDELIHKADEVTLSEAGSTAGPAEPRGLAEDVTR----TTPSRR------EITGVEAQPGEATSGPPGIQPGQEPPVTMVFMGYQNVEDEAETKKVLGLQDT-IKAELVVIED-------AATPREPAPLNGSAAELP---ATKEENQTGPTTTPSDTQDLDMK-KPRCRCCSVM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75781-1", "uniprot_id": "PALM_HUMAN", "id": "O75781-1", "name": "Paralemmin-1", "aln": "MEVLAAETTSQQERLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSSASEGDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENAAAPSPVRAPAPSPAKEERKTEVVMNSQQTPVGTPKDKRVSNTPLRTVDGSPMMKAAMYSVEITVEKDKVTGETRVLSSTTLLPRQPLPLGIKVYEDETKVVHAV---DGTAENGIHPLSSSEVDELIHKADEVTLSEAGSTAGAAETRGAVEGAAR----TTPSRR------EITGVQAQPGEATSGPPGIQPGQEPPVTMIFMGYQNVEDEAETKKVLGLQDT-ITAELVVIED-------AAEPKEPAPPNGSAAEPPTEAASREENQAGPEATTSDPQDLDMK-KHRCKCCSIM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B2U8-1", "uniprot_id": "A0A8M2B2U8_DANRE", "id": "A0A8M2B2U8-1", "name": "Paralemmin-1", "aln": "--MEMSESVSQQERLQAIAEKRKRQTEIENKKRQLEDDRRQLQHLKSKALRERWLLDGAPSAGQEEDE-TTKQLREHEAKTRGLEETIVSLERELEELETGVSATST-KEN-----------LSDALQEINTKTVEKMVVTESVKEVKVHVSPRLEKSGGVSDMMRAAMYSVEITVEKDLVTGETKVLSTNTLLPKDLSQQGVKVYEDEQKVVHEVRSVDGTVTNGVHQLSSSEVDELLHKADEVTMGESSKTTPRLE-RGQAEKEEKHEKDVTPAEASSTPIMEITGVEAKPAAPQTEVSGAS--AENPVTMVFMGYQSVEDEDETKKVLGMESTTVKAEVVLIEDGEGKNAGSDTKQEQAPPNGSPAEAD----KAEEAARESEQPEGDNAEVKSKEKQPCKCCTIM", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :::.*************::*:***.*:*****:*****:************:*:**:..* ** :*:::.* *:* **::: **:*:: ** * **.:: *** * * :* :::.: : * . . : * :: . * **:************* *****:***:.*:**:: *:****** **** * ** **:: *********:*******:.*:..*: * ** .* : .**:. *****:*:*. . : .* . * ****:*****.**** *******::.* :.**:*:*** : :* ** ***.** . ** . . .* ::. * * *:**::*", "identical_positions": 188, "similar_positions": 96, "identity": "45.97%" }, { "cls_id": "homologset.agr.MGI:1261819", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88509-1", "uniprot_id": "DNM3B_MOUSE", "id": "O88509-1", "name": "DNA (cytosine-5)-methyltransferase 3B", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKGDS-----------------RHLNEEE-----------GASGYEECIIVNGNFSDQSSDTKDAPSPPVLEAICTEPVCTPETRGRRSSSRLSKREVSSLLNYTQDMTGDGD-----------RDDEVDDGNGSDILMP-KLTRETKDTRTRSES--------------------------------------------PAVRTRHSNGTSSLERQRASPRITRGRQGRHHVQEYPVEFPATRSRRRRASSSASTPWSSPAS------VDFMEEVT-----PKSVSTPSVDLSQDGDQEGMD------------------------------------------TTQVDAESRDGDSTEYQDDKEFGIGDLVWGKIKGFSWWPAMVVSWKATSKRQAMPGMRWVQWFGDGKFSEISADKLVALGLFSQHFNLATFNKLVSYRKAMYHTLEKARVRAGKTFSSSPGESLEDQLKPMLEWAHGGFKPTGIEGLKPNKKQPVVNKSKVRRSDSRNLEPRRRENKSRRRTTNDSAASE-SPPPKRLKTNSYG-GKDRGEDEESRERMASEVTNNKGNLEDRCLSCGKKNPVSFHPLFEGGLCQSCRDRFLELFYMYDEDGYQSYCTVCCEGRELLLCSNTSCCRCFCVECLEVLVGAGTAEDAKLQEPWSCYMCLPQRCHGVLRRRKDWNMRLQDFFTTDPDLEEFE-PPKLYPAIPAAKRRPIRVLSLFDGIATGYLVLKELGIKVEKYIASEVCAESIAVGTVKHEGQIKYVNDVRKITKKNIEEWGPFDLVIGGSPCNDLSNVNPARKGLYEGTGRLFFEFYHLLNYTRPKEGDNRPFFWMFENVVAMKVNDKKDISRFLACNPVMIDAIKVSAAHRARYFWGNLPGMNRPVMASKNDKLELQDCLEFSRTAKLKKVQTITTKSNSIRQGKNQLFPVVMNGKDDVLWCTELERIFGFPAHYTDVSNMGRGARQKLLGRSWSVPVIRHLFAPLKDYFACE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AVL3-1", "uniprot_id": "A0A8I6AVL3_RAT", "id": "A0A8I6AVL3-1", "name": "DNA (cytosine-5)-methyltransferase 3B", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKGDS-----------------RHLNEEE-----------GASGYEDCIIVNGNCSDQSSDTKDAPSPPVLEAICTEPVCTPETRGRRSSSRLSKREVSSLLNYTQDVVGDG-------------DGEADDGDGSDILMMPKLTRETKDARTPSES--------------------------------------------PAVRTRNSNSISSLERQRTSPRITRGRQGRYHVQEYPVEFPATKSRRRRASSSASTPWSSPAS------IELMEDVT-----PKSSSTPSVDLSQDGPQEGMD------------------------------------------ATQVDAESRDGDSTEYQDDKEFGIGDLVWGKIKGFSWWPAMVVSWKATSKRQAMPGMRWVQWFGDGKFSEIAADKLVALGLFSQHFNLATFNKLVSYRKAMYHTLEKAMVRAGKTFPSRPGDSLEDQLKPMLEWAHGGFKPTGIEGLKPNNKQP--------------------ENKSRRRTTIDFAASEYSTPPKRLKTNSYG-GKDRGEDEESRERMASDVTNNKGNLEDRCLSCGKKNPVSFHPLFEGGLCQSCRDRFLELFYMYDEDGYQSYCTVCCEGRELLLCSNTSCCRCFCVECLEVLVGTGTAEDAKLQEPWSCYMCLPQRCHGVLRRRKDWNMRLQDFFTTDPDLEEFQEPPKLYPAIPAAKRRPIRVLSLFDGIATGYLVLKDLGIKVEKYVASEVCAESIAVGTIKHEGQIKYVNDVRKITKKNIEEWGPFDLVIGGSPCNDLSNVNPARKGLYEGTGRLFFEFYHLLNYTRPKEGDNRPFFWMFENVVAMKVNDKKDISRFLACNPVMIDAIKVSAAHRARYFWGNLPGMNRPVIASKNDKLELQDCLEFSRTAKLKKVQTITTKSNSIRQGKNQLFPVVMNGKDDVLWCTELERIFGFPAHYTDVSNMGRGARQKLLGRSWSVPVIRHLFAPLKDYFACE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UBC3-1", "uniprot_id": "DNM3B_HUMAN", "id": "Q9UBC3-1", "name": "DNA (cytosine-5)-methyltransferase 3B", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKGDT-----------------RHLNGEE-----------DAGGREDSILVNGACSDQSSD-----SPPILEAIR-----TPEIRGRRSSSRLSKREVSSLLSYTQDLTGDG---------------DGEDGDGSDTPVMPKLFRET---RTRSES--------------------------------------------PAVRTRNNNSVSSRERHRPSPRSTRGRQGRNHVDESPVEFPATRSLRRRATASAGTPWPSPPSSY--LTIDLTDDTEDTHGTPQSSSTPYARLAQDSQQGGME------------------------------------------SPQVEADSGDGDSSEYQDGKEFGIGDLVWGKIKGFSWWPAMVVSWKATSKRQAMSGMRWVQWFGDGKFSEVSADKLVALGLFSQHFNLATFNKLVSYRKAMYHALEKARVRAGKTFPSSPGDSLEDQLKPMLEWAHGGFKPTGIEGLKPNNTQPVVNKSKVRRAGSRKLESRKYENKTRRRTADDSATSDYCPAPKRLKTNCYNNGKDRGDEDQSREQMASDVANNKSSLEDGCLSCGRKNPVSFHPLFEGGLCQTCRDRFLELFYMYDDDGYQSYCTVCCEGRELLLCSNTSCCRCFCVECLEVLVGTGTAAEAKLQEPWSCYMCLPQRCHGVLRRRKDWNVRLQAFFTSDTGLEYEA--PKLYPAIPAARRRPIRVLSLFDGIATGYLVLKELGIKVGKYVASEVCEESIAVGTVKHEGNIKYVNDVRNITKKNIEEWGPFDLVIGGSPCNDLSNVNPARKGLYEGTGRLFFEFYHLLNYSRPKEGDDRPFFWMFENVVAMKVGDKRDISRFLECNPVMIDAIKVSAAHRARYFWGNLPGMNRPVIASKNDKLELQDCLEYNRIAKLKKVQTITTKSNSIKQGKNQLFPVVMNGKEDVLWCTELERIFGFPVHYTDVSNMGRGARQKLLGRSWSVPVIRHLFAPLKDYFACE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BEF6-1", "uniprot_id": "A0A8M2BEF6_DANRE", "id": "A0A8M2BEF6-1", "name": "DNA (cytosine-5-)-methyltransferase", "aln": "MATNVSLEPNNPDDKCSRYEVLGWINETLQTNFTQVEQCRSGACFCQLIDLLFPGTINLKKVKFESQKRSDFMQNYGLLQAAFRDLEVTEPVPVNELLSGKFRPNFTYLKWFKKFFYANVKQERVYNAFEARDGQEIVPVDDVMKSPKALKSSYESGRAGEESDMEINGGRRSATYDPKWQRNLKWIRASDMGDNYAYCTTCDYNIILLAGFHDLKRHQLTQNHMKHETGRTNLPGRKQIEESISCSETMLLFIQSHCLSSLPSRINRVSQRTARCILGLKYPNDIVSACKLNPYCIYIYGQVPLDVKTGDKTNCHVVLAGFFEEKQARYCIRFLDVFQPEDSASSVSGGLFSILKKFEIPASNMVAVYINDHELTSESVVSQIRELNPQVIDLGGLYSIPDTACSAGLQTHSVQVQELIANIYRHFSTGSTSNDNLKMLFAGIDGLKVHSNPLSNSEEFCVLVKRIHEMWSDLVSYFSSCDENNDNVKQICSQLENPKIRLTLMFLDQALGPLRAFGQHLQQSKSSVRADLVEILREASGLLRSYASSFLRPQAVIRYLKEQDPAILDNEAFCLPAAELSLGGVLEDFISAREEELADFLSTFYNECLAIYKTLTTSIAASLPLSDSVLRAISQLLSPAGRLKVTGKNIVDLAVRFGFCSKPEDSAKLNDEFLEYQLAEEENLSSTHSIERYWCTVLKTFPPTSVFKRLVLCLLVLPSPSLDATKIFAQAIENGDADQLDDSSSESDTDMTKELDSNDDNSLDNSELQISPIKNGIMKKSRRSTSETVQHSNAVKPCVVRLEKITSQREVNLKNDGAKNDGTLTSNTLKEDSIRGIHGWECSLRQKPQARTVFQAGAGTWSKPAIQDVDRKPEAVKNDLSNSTPSPRRGKRDQAYNDGKGFAVGELVWGKVKDFSLWPGLVVPWKG---RIVPVSMRRVEWFGDGMFSEIHTDGLLPFGAFSKNFCSKSYEGLPTYKNAIYQILELAAERSGKLFP--PSEKKGEEVKAMMDWAFGGFQPMGADGFLPS-----------------------ADSSASNKTESDSSVSDYQPPAKRKYVFKNR----PSTQECNRDQMVQEVTSKGRKIEDFCLSCGSSNTEIFHPLFKGSLCIKCKENFTETLYRYDDDGYQSYCTVCCAGLEVILCGNASCCRCFCKDCLNVLVGPGTFDKLKEVDPWSCYVCLPSKCYGVLKLRTDWSVRVQEFFANNSAFEFEP--HRVYPSIPAHKRRPIRVLSLFDGIATGYLVLKDLGFKLERYIASEICEDSIAVGMVKHEGKIEYVKDVRTITRKHLAEWGPFDLLIGGSPCNDLSMVNPARKGLFEGTGRLFFEYYRMLTMMRPKEDDDRPFFWLFENVVAMSAHDKADICRFLECNPVMIDAVKVSPAHRARYFWGNLPGMNRPVATSLTDNVDLQDCLESGRTAMFSKVRTITTKSNSIKQGKTGPLPVTMNGKEDYLWCTEMEKIFGFPKHYTDVNNMGRGQRQKVLGRSWSVPVIRHLFAPLKDYFACE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : *:*: :: *. . :::. * :..: *. *.: *.. . . * * :*.**. : : * :... .* : :* .* * * . * : .... *. : : . .. .:: *:: :. ** :: :. . . .. : :. .:. .* ::. *:. : .. : . . *:*.* *.:*:*****:*.** **.:**.**. * . .** *:***** ***: :* *:.:* **::* ::: * :*::*:*: ** * *:** *. *.:. :::*.*::**.***:* * :*: *. :..: .:* * :.*: ...** . . :: .*::*..:*:.: .:** ***** .*. *****:*.** .*::.* * :* **:*********** * *::**.*:******* :**:****.** . * :*****:***.:*:***: *.**.:*:* **:.:. :* ::**:*** :*********************:**:*: :*:***:* :***** :****:*:**:***.**:*:: *******:********** ********:*********:*::*. ****.*:*****:*******.. ** **.*** ********:***.****************** :* .*:::****** .* * :.**:*********:***. :**.****:* *****:*:***** *****.***** ***:************************", "identical_positions": 387, "similar_positions": 238, "identity": "25.23%" }, { "cls_id": "homologset.agr.MGI:1261820", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97536-1", "uniprot_id": "CAND1_RAT", "id": "P97536-1", "name": "Cullin-associated NEDD8-dissociated protein 1", "aln": "MASASYH-ISNLLEKMTSSDKDFRFMATNDLMTELQKDSIKLDDDSERKVVKMILKLLEDKNGEVQNLAVKCLGPLVSKVKEYQVETIVDTLCTNMLSDKEQLRDISSIGLKTVIGELPPASSGSALAANVCKKITGRLTSAIAKQEDVSVQLEALDIMADMLSRQGGLLVNFHPSILTCLLPQLTSPRLAVRKRTIIALGHLVMSCGNIVFVDLIEHLLSELSKNDSMSTTRTYIQCIAAISRQAGHRIGEYLEKIIPLVVKFCNVDDDELREYCIQAFESFVRRCPKEVYPHVSTIINICLKYLTYDPNYNYDDEDEDE-NAMDADGGDDDDQGSDDEYSDDDDMSWKVRRAAAKCLDAVVSTRHEMLPEFYKTVSPALISRFKEREENVKADVFHAYLSLLKQTRPVQSWLCDPDAMEQGETPLTMLQSQVPNIVKALHKQMKEKSVKTRQCCFNMLTELVNVLPGALTQHIPVLVPGIIFSLNDKSSSSNLKIDALSCLYVILCNHSPQVFHPHVQALVPPVVACVGDPFYKITSEALLVTQQLVKVIRPLDQ---PSSFDATPYIKDLFTCTIKRLKAADIDQEVKERAISCMGQIICNLGDNLGPDLSNTLQIFLERLKNEITRLTTVKALTLIAGSPLKIDLRPVLGEGVPILASFLRKNQRALKLGTLSALDILIKNYSDSLTAAMIDAVLDELPPLISESDMHVSQMAISFLTTLAKVYPSSLSKISGSILNELIGLVRSPLLQGGALSAMLDFFQALVVTGTNNLGYMDLLRMLTGPVY-------SQSTALT-------HKQSYYSIAKCVAALTRACPKEGPAVVGQFIQDVKNSRSTDSIRLLALLSLGEVGHHIDLSGQLELKSVILEAFSSPSEEVKSAASYALGSISVGNLPEYLPFVLQEITSQPKRQYLLLHSLKEIISSASVVG-----LKPYVENIWALLLKHCECAEEGTRNVVAECLGKLTLIDPETLLPRLKGYLISGSSYARSSVVTAVKFTISDHPQPIDPLLKNCIGDFLKTLEDPDLNVRRVALVTFNSAAHNKPSLIRDLLDSVLPHLYNETKVRKELIREVEMGPFKHTVDDGLDIRKAAFECMYTLLDSCLDRLDIFEFLNHVEDGLKDHYDIKMLTFLMLVRLSTLCPSAVLQRLDRLVEPLRATCTTKVKANSVKQEFEKQDELKRSAMRAVAALLTIPEAEKSPLMSEFQSQISSNPELAAIFESIQKD--SSSTNLESMDTS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q86VP6-1", "uniprot_id": "CAND1_HUMAN", "id": "Q86VP6-1", "name": "Cullin-associated NEDD8-dissociated protein 1", "aln": "MASASYH-ISNLLEKMTSSDKDFRFMATNDLMTELQKDSIKLDDDSERKVVKMILKLLEDKNGEVQNLAVKCLGPLVSKVKEYQVETIVDTLCTNMLSDKEQLRDISSIGLKTVIGELPPASSGSALAANVCKKITGRLTSAIAKQEDVSVQLEALDIMADMLSRQGGLLVNFHPSILTCLLPQLTSPRLAVRKRTIIALGHLVMSCGNIVFVDLIEHLLSELSKNDSMSTTRTYIQCIAAISRQAGHRIGEYLEKIIPLVVKFCNVDDDELREYCIQAFESFVRRCPKEVYPHVSTIINICLKYLTYDPNYNYDDEDEDE-NAMDADGGDDDDQGSDDEYSDDDDMSWKVRRAAAKCLDAVVSTRHEMLPEFYKTVSPALISRFKEREENVKADVFHAYLSLLKQTRPVQSWLCDPDAMEQGETPLTMLQSQVPNIVKALHKQMKEKSVKTRQCCFNMLTELVNVLPGALTQHIPVLVPGIIFSLNDKSSSSNLKIDALSCLYVILCNHSPQVFHPHVQALVPPVVACVGDPFYKITSEALLVTQQLVKVIRPLDQ---PSSFDATPYIKDLFTCTIKRLKAADIDQEVKERAISCMGQIICNLGDNLGSDLPNTLQIFLERLKNEITRLTTVKALTLIAGSPLKIDLRPVLGEGVPILASFLRKNQRALKLGTLSALDILIKNYSDSLTAAMIDAVLDELPPLISESDMHVSQMAISFLTTLAKVYPSSLSKISGSILNELIGLVRSPLLQGGALSAMLDFFQALVVTGTNNLGYMDLLRMLTGPVY-------SQSTALT-------HKQSYYSIAKCVAALTRACPKEGPAVVGQFIQDVKNSRSTDSIRLLALLSLGEVGHHIDLSGQLELKSVILEAFSSPSEEVKSAASYALGSISVGNLPEYLPFVLQEITSQPKRQYLLLHSLKEIISSASVVG-----LKPYVENIWALLLKHCECAEEGTRNVVAECLGKLTLIDPETLLPRLKGYLISGSSYARSSVVTAVKFTISDHPQPIDPLLKNCIGDFLKTLEDPDLNVRRVALVTFNSAAHNKPSLIRDLLDTVLPHLYNETKVRKELIREVEMGPFKHTVDDGLDIRKAAFECMYTLLDSCLDRLDIFEFLNHVEDGLKDHYDIKMLTFLMLVRLSTLCPSAVLQRLDRLVEPLRATCTTKVKANSVKQEFEKQDELKRSAMRAVAALLTIPEAEKSPLMSEFQSQISSNPELAAIFESIQKD--SSSTNLESMDTS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6ZQ38-1", "uniprot_id": "CAND1_MOUSE", "id": "Q6ZQ38-1", "name": "Cullin-associated NEDD8-dissociated protein 1", "aln": "MASASYH-ISNLLEKMTSSDKDFRFMATNDLMTELQKDSIKLDDDSERKVVKMILRLLEDKNGEVQNLAVKCLGPLVSKVKEYQVETIVDTLCTNMLSDKEQLRDISSIGLKTVIGELPPASSGSALAANVCKKITGRLTSAIAKQEDVSVQLEALDIMADMLSRQGGLLVNFHPSILTCLLPQLTSPRLAVRKRTIIALGHLVMSCGNIVFVDLIEHLLSELSKNDSMSTTRTYIQCIAAISRQAGHRIGEYLEKIIPLVVKFCNVDDDELREYCIQAFESFVRRCPKEVYPHVSTIINICLKYLTYDPNYNYDDEDEDE-NAMDADGGDDDDQGSDDEYSDDDDMSWKVRRAAAKCLDAVVSTRHEMLPEFYKTVSPALIARFKEREENVKADVFHAYLSLLKQTRPVQSWLCDPDAMEQGDTPLTMLQSQVPNIVKALHKQMKEKSVKTRQCCFNMLTELVNVLPGALTQHIPVLVPGIIFSLNDKSSSSNLKIDALSCLYVILCNHSPQVFHPHVQALVPPVVACVGDPFYKITSEALLVTQQLVKVIRPLDQ---PSSFDATPYIKDLFTCTIKRLKAADIDQEVKERAISCMGQIICNLGDNLGPDLSNTLQIFLERLKNEITRLTTVKALTLIAGSPLKIDLRPVLGEGVPILASFLRKNQRALKLGTLSALDILIKNYSDSLTAAMIDAVLDELPPLISESDMHVSQMAISFLTTLAKVYPSSLSKISGSILNELIGLVRSPLLQGGALSAMLDFFQALVVTGTNNLGYMDLLRMLTGPVY-------SQSTALT-------HKQSYYSIAKCVAALTRACPKEGPAVVGQFIQDVKNSRSTDSIRLLALLSLGEVGHHIDLSGQLELKSVILEAFSSPSEEVKSAASYALGSISVGNLPEYLPFVLQEITSQPKRQYLLLHSLKEIISSASVAG-----LKPYVENIWALLLKHCECAEEGTRNVVAECLGKLTLIDPETLLPRLKGYLISGSSYARSSVVTAVKFTISDHPQPIDPLLKNCIGDFLKTLEDPDLNVRRVALVTFNSAAHNKPSLIRDLLDSVLPHLYNETKVRKELIREVEMGPFKHTVDDGLDIRKAAFECMYTLLDSCLDRLDIFEFLNHVEDGLKDHYDIKMLTFLMLVRLSTLCPSAVLQRLDRLVEPLRATCTTKVKANSVKQEFEKQDELKRSAMRAVAALLTIPEAEKSPLMSEFQSQISSNPELAAIFESIQKD--SSSTNLESMDTS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9VKY2-1", "uniprot_id": "CAND1_DROME", "id": "Q9VKY2-1", "name": "Cullin-associated NEDD8-dissociated protein 1", "aln": "MASHQYHQIANLLEKMTSTDKDFRFMATNDLMTELQKDSIILDDESEKKVVRMVLKLLEDKNGEVQNLAVKCLGPLVNKVKEIQVETIVDSLCANMMSNTEQLRDISSIGLKTVIAELPQSS--NSLAPNVCQRITGKLSTAIEK-EDVSVKLESLDILADLLSRFGEFLVPFHSTILKALMPQLASSRQAVRKRTIVALSFLLIQANSNAYNGVIDHLLDGLENPPNPAAIRTYIQCLASICRQAGHRLCNHIDRSMLLLSQYSQRDDDELREFCLQACEAFVMRCPDAINPHIPMILELCLNYITYDPNYNYETDDGDTGNAMDTE---DDEYVDSEEYSDDDDMSWKVRRAAAKCLEVLISTRQELVEDFYRSLSPALIARFKEREENVKSDIFHAYVALLKNTRLTDDVANDHDSMDQVSGPTSLLIEQLPLIVKAIQPLMREKSMKTRQDCFLLLRELLNSLPGALGPYLDSIVPGISYSLNDKSSTSNMKIESLGFLYSLLQGHPPHVFHPHIPLLVPLVVTSVFDPFYKIATEALLVLQQLVKVIRPLEPNAAKSDFDAPSFVGQVYSCTLQKLKVTDVDQEVKERAIACMGQIIANMGDMLQNELAVCLPIFMERLKNEVTRLSSVKALTLIAASSLRIDLTPILHDVLPALGTFLRKNHRALKLHSLDLINKIVINYSSNFEANLLQTAIVEIPPLISDSDLHVAQYSLTLLSTVARRQPQALVGIHEQFLRSVLILVRSPLLQGSALNCTLELFQALVQTQLSGLDYHSLVSKLMAPVLGGNGDVKSRATAGAPSEVVQLHKQAYHSSAKCIAALTQQCPQVATPLATKLITDLQ--KRNDTEIIFCLLTIGEIGRHFDLSSIQVLPQTIIECFGATSEDVKAAASHALGAVSVGSLQTYLPLILHEIEVQPKRQYLLLHSLKEVISSLSVSPSGLAQLLPSVPSIWDQLFKHCECSEEGSRNVVAECLGKLVLVNPDELLPQLQQALRSESATMRTVVVSSVKFTISDQPQPIDVLLKQNIGEFLFALRDPEPQVRRVALVAFNSAVHNKPSLVRDLLPTLLPWLYSETKVKSELIREVEMGPFKHTVDDGLDIRKAAFECMYTLLEQGLDRVDVMQFLDHVQAGLCDHYDIKMLTYLMTARLAILCPDKVLLRLDQFIQQLRDTCTHKVKANSVKQEYEKQDELKRSALRAVSALSQIPKANKNQQLVDFLKSIKETPELNKIFEYIQKDSITGSSDIIVMDQS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** .** *:********:********************* ***:**:***:*:*:*********************.**** *******:**:**:*:.***************.*** :* .:**.***::***:*::** * *****:**:***:**:*** * :** **.:**..*:***:*.* *******:**..*::.... .: .:*:***. *.: . :: ******:*:*.******: ::::: : *: ::.: *******:*:** *:** ***. : **:. *:::**:*:********: :* * ****:: **: ..:********************:.::***:*:: :**:::*****:**********:*:****::***:** .:. * *:*:* . * ::* .*:* ****:: *:***:**** ** :* **:* ***** :: :**** :*******:**:**::*. ** :* .*.*:*****: *** **:.* ******::***** **********: *.***..:: ::::**:::**.:*:*********:******.*:** * :*. * **:******:***::********.*.*:*** *:* : :* *.:*****:***** :*. :: :: ***..: * ::::.: *:*****:**:**:* ::::*:*:*: *.:* * .:*..:: *********.**.. *::***** * ..*.* .*: * .** *::** : ***:*:* ***:****: **: ...:. ::* *:: : .*: ::.**::**:*:*:***. * ..*:*.*.:.**:**:***:***::***.* ***::*:** **************:*** ** * * * .** *:*****:***:***********.*::*: ***:*: * * *: *: **::*******:***** ***: **:** :*.**: :*******:****.******:**** ::** **.****:.*********************************:. ***:*:::**:**: ** *********:** .**: ***. ** ***:::: ** *** **********:**********:***:** **:*:*. : :* ..*...*** *** **** :.*::: ** *", "identical_positions": 733, "similar_positions": 330, "identity": "58.36%" }, { "cls_id": "homologset.agr.MGI:1261827", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q1LZ53-1", "uniprot_id": "DNM3A_RAT", "id": "Q1LZ53-1", "name": "DNA (cytosine-5)-methyltransferase 3A", "aln": "---MPS----SGPGDTSISSLEREDD-RKEGEEQEENRGKEERQEPSATARKVGRPGRKRKHPPVESSDTPKDPAVTTKSQPTAQDSGPSDLLPNGDLEKRSEPQPEEGSPAAGQK---GGAPAEGEG-TETPPEASR--AVENGCCVT-----------------KEGRGASAGEGKEQKQTNIES---MKMEGSRGRLRGGLGWESSLRQRPMPRLTFQAGDPYYISKRKRDEWLARWKREAEKKAKVIAVMNAVEES------------------------------------------QASGESQKVEEASPP-----AVQQPTDPASPTVATTPEPVGADAGDKNATKAADDEPEYEDGRGFGIGELVWGKLRGFSWWPGRIVSWWMTGRSRAAEGTRWVMWFGDGKFSVVCVEKLMPLSSFCSAFHQATYNKQPMYRKAIYEVLQVASSRAGKLFPACHDSDESDTGKAVEVQNKQMIEWALGGFQPSGPKGLEPPEEEKNPYKEVYTDMWVEPEAAAYAPPPPAKKPRKS-TTEKPKVKEIIDERTRERLVYEVRQKCRNIEDICISCGSLNVTLEHPLFIGGMCQNCKNCFLECAYQYDDDGYQSYCTICCGGREVLMCGNNNCCRCFCVECVDLLVGPGAAQAAIKEDPWNCYMCGHKGTYGLLRRREDWPSRLQMFFANNHDQEFDPPKVYPPVPAEKRKPIRVLSLFDGIATGLLVLKDLGIQVDRYIASEVCEDSITVGMVRHQGKIMYVGDVRSVTQKHIQEWGPFDLVIGGSPCNDLSIVNPARKGLYEGTGRLFFEFYRLLHDARPKEGDDRPFFWLFENVVAMGVSDKRDISRFLESNPVMIDAKEVSAAHRARYFWGNLPGMNRPLASTVNDKLELQECLEHGRIAKFSKVRTITTRSNSIKQGKDQHFPVFMNEKEDILWCTEMERVFGFPVHYTDVSNMSRLARQRLLGRSWSVPVIRHLFAPLKEYFACV--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88508-1", "uniprot_id": "DNM3A_MOUSE", "id": "O88508-1", "name": "DNA (cytosine-5)-methyltransferase 3A", "aln": "---MPS----SGPGDTSSSSLEREDD-RKEGEEQEENRGKEERQEPSATARKVGRPGRKRKHPPVESSDTPKDPAVTTKSQPMAQDSGPSDLLPNGDLEKRSEPQPEEGSPAAGQK---GGAPAEGEG-TETPPEASR--AVENGCCVT-----------------KEGRGASAGEGKEQKQTNIES---MKMEGSRGRLRGGLGWESSLRQRPMPRLTFQAGDPYYISKRKRDEWLARWKREAEKKAKVIAVMNAVEEN------------------------------------------QASGESQKVEEASPP-----AVQQPTDPASPTVATTPEPVGGDAGDKNATKAADDEPEYEDGRGFGIGELVWGKLRGFSWWPGRIVSWWMTGRSRAAEGTRWVMWFGDGKFSVVCVEKLMPLSSFCSAFHQATYNKQPMYRKAIYEVLQVASSRAGKLFPACHDSDESDSGKAVEVQNKQMIEWALGGFQPSGPKGLEPPEEEKNPYKEVYTDMWVEPEAAAYAPPPPAKKPRKS-TTEKPKVKEIIDERTRERLVYEVRQKCRNIEDICISCGSLNVTLEHPLFIGGMCQNCKNCFLECAYQYDDDGYQSYCTICCGGREVLMCGNNNCCRCFCVECVDLLVGPGAAQAAIKEDPWNCYMCGHKGTYGLLRRREDWPSRLQMFFANNHDQEFDPPKVYPPVPAEKRKPIRVLSLFDGIATGLLVLKDLGIQVDRYIASEVCEDSITVGMVRHQGKIMYVGDVRSVTQKHIQEWGPFDLVIGGSPCNDLSIVNPARKGLYEGTGRLFFEFYRLLHDARPKEGDDRPFFWLFENVVAMGVSDKRDISRFLESNPVMIDAKEVSAAHRARYFWGNLPGMNRPLASTVNDKLELQECLEHGRIAKFSKVRTITTRSNSIKQGKDQHFPVFMNEKEDILWCTEMERVFGFPVHYTDVSNMSRLARQRLLGRSWSVPVIRHLFAPLKEYFACV--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y6K1-1", "uniprot_id": "DNM3A_HUMAN", "id": "Q9Y6K1-1", "name": "DNA (cytosine-5)-methyltransferase 3A", "aln": "MPAMPS----SGPGDTSSSAAEREED-RKDGEEQEEPRGKEERQEPSTTARKVGRPGRKRKHPPVESGDTPKDPAVISKSPSMAQDSGASELLPNGDLEKRSEPQPEEGSPAGGQK---GGAPAEGEGAAETLPEASR--AVENGCCTP-----------------KEGRGAPAEAGKEQKETNIES---MKMEGSRGRLRGGLGWESSLRQRPMPRLTFQAGDPYYISKRKRDEWLARWKREAEKKAKVIAGMNAVEEN------------------------------------------QGPGESQKVEEASPP-----AVQQPTDPASPTVATTPEPVGSDAGDKNATKAGDDEPEYEDGRGFGIGELVWGKLRGFSWWPGRIVSWWMTGRSRAAEGTRWVMWFGDGKFSVVCVEKLMPLSSFCSAFHQATYNKQPMYRKAIYEVLQVASSRAGKLFPVCHDSDESDTAKAVEVQNKPMIEWALGGFQPSGPKGLEPPEEEKNPYKEVYTDMWVEPEAAAYAPPPPAKKPRKS-TAEKPKVKEIIDERTRERLVYEVRQKCRNIEDICISCGSLNVTLEHPLFVGGMCQNCKNCFLECAYQYDDDGYQSYCTICCGGREVLMCGNNNCCRCFCVECVDLLVGPGAAQAAIKEDPWNCYMCGHKGTYGLLRRREDWPSRLQMFFANNHDQEFDPPKVYPPVPAEKRKPIRVLSLFDGIATGLLVLKDLGIQVDRYIASEVCEDSITVGMVRHQGKIMYVGDVRSVTQKHIQEWGPFDLVIGGSPCNDLSIVNPARKGLYEGTGRLFFEFYRLLHDARPKEGDDRPFFWLFENVVAMGVSDKRDISRFLESNPVMIDAKEVSAAHRARYFWGNLPGMNRPLASTVNDKLELQECLEHGRIAKFSKVRTITTRSNSIKQGKDQHFPVFMNEKEDILWCTEMERVFGFPVHYTDVSNMSRLARQRLLGRSWSVPVIRHLFAPLKEYFACV--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1R1K5-1", "uniprot_id": "F1R1K5_DANRE", "id": "F1R1K5-1", "name": "DNA (cytosine-5-)-methyltransferase", "aln": "---MPSNTVATAAAAFKSSDFNCDTNGNQMNESSMETMIIDEMPSLCTPVRKVGRPGRKRKHLHVTCYGPLNQLMAKQHKEAELQSSLQS---QNGEVERHENKSIEGRHSTLDKRDVENGLFCQSGCKAESTSDSSLSPSLENGFVSSQDSEKCDEETLPTLPRKKRGRRKLERPTKYVEHKEDESGDPSKNEGARGRLRGGVGWEVSLRQRPMPRVTFQAGDPYYISRRTREELLAKWKLEAEKKAKLVSVMNSMEDHGEVESEPKKDVITVPLLFPPPMPPTPPTPPMQQQPPQPQAQHQTNLKPQPSPQQQPPPFQQQQQQQPTDPASPTVATTPEPVSIGDGDKTSPKS--TESEYEDGRGFGINELVWGKLRGYSWWPGRVVSWRMTRRSPAAEGTRWVTWFGDGKFSVVCVEKLLPLSSFHNAFHQPTYNKQPMYKKAIFEVLQVASTRAGKTFLSCPASDDTDSSKLVDVENKKMIEWAMSGFQPTGPKGLDPPESE--PYEMC---EWVEPEAASYLPPP-AKKPRKSTVTEKPKVKEMIDERTRERLVFDVRQKCRNIEDICISCGSLYVSLEHPLFIGGMCQSCTNCFLECAYQYDDDGYQSYCTICCGGREVLMCGNNNCCRCFCVECVDLLVGPGAAQAAIKEDPWNCYMCGLKTQYGLLERRADWPCRLQHFFANNHDQEFEPPRLYPPVLAENRKPIRVLSLFDGIATGLLVLRELGIQVERYVASEVCEDSITVGIVRHQGRIMYVGDVRQLTRKNIQEWGPFDLVIGGSPCNDLSIVNPARKGLYEGTGRLFFEFYRLLHEARPKEGDTRPFFWLFENVVAMGVSDKRDISRFLECNPVMIDAKEVSAAHRARYFWGNLPGMNRPMSAMCTDKLDLQDCLEHGRTAKFGKVRTITTRSNSIKQGKDQHFPVFMNDKEDILWCTEMERVFGFPVHYTDVSNMSRLARQRLLGRSWSVPVIRHLFAPLKEYFACVGT", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *** :... . * : : : .: .*.. * :* . .:..************ * . .. :: . :. . *.* * **::*::.: . * .: .:: .* .:. :*: .::* ::*** . *.** * :..: ** * **:*******:*** *********:***********:*.*:* **:** *******::: **::*: * :.* : .** ******************. . ***.:.*: *.**********.*********:******:*** ** ** ******** ***************:***** .****.********:***:*******:**** * * **::*:.* *:*:** *****:.****:*****:***.* **: *******:* *** ******* .:*******:**********::****************** *:******:*****.*.********************************************************************* * ****.** ***.*** **********:**::**** **:********************::*****:**:************:*****:********.:*:*:*********************************************:******* **************************.*****************************::: .***:**:****** ***.*************************:********************************************************** ", "identical_positions": 656, "similar_positions": 139, "identity": "66.13%" }, { "cls_id": "homologset.agr.MGI:1261831", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P54256-1", "uniprot_id": "HAP1_RAT", "id": "P54256-1", "name": "Huntingtin-associated protein 1", "aln": "MRPKDQVQSSAGDGTGSGDPATGTPTTQPAADPAPEPSAEPKP-APAQGTGS----------------------GQKSGSRTKTGGSFCRSRIR---GDSDAPWTRYIFQGPYGPRATGLGTGRAEGIWKTPAAYIGRRPGVSGPERAAFIR-ELQEALCPN-PLPRKKITEDDIKVMLYLLEE----------------KERDLNTAARIGQSLVKQNSVLMEENNKLETMLGSAREEILHLRKQVNLRDDLLQLYSDSDDDEEDEEDEEEE-EGEEEEREGQRDQDQQHDHPYGAPKPPPKAETLH--HCPQLEALKQKLKLLEEENDHLREEASHLDNLED----KEQMLILECVEQFSEASQQMAELSEVLVLRLEGYERQQKEITQLQAEITKLQQRCQSYGAQTEKLQQQLASEK-------GVHPESLRAGSHMQDYGSRPRER------------QEDGKSHRQRSSMPAGSVTHYGYSVPLDALPSFPETLAEELRTSLRKFITDPAYFMER-------------CDTRCREERKKEQGTMPPP------------PVQDLKPPEDFEAPEELVPEEELGAIEEVGTAEDGPAEETEQASEETEAWEEVEPEVDEATRMNVVVSALEASG---------LGPSHLDMK---YVLQQLSNWQDAHSKRQQKQKVVPKDSPAPQQQTNMGGGIVEQQPIVPTQDSQRLEEDRATHSPSAREEEGPSGAT--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35668-1", "uniprot_id": "HAP1_MOUSE", "id": "O35668-1", "name": "Huntingtin-associated protein 1", "aln": "MRPKEQVQSGAGDGTGSGDPAAGTPTTQPAVGPAPEPSAEPKP-APAQGTGS----------------------GQKSGSRTKTG-SFCRSMII---GDSDAPWTRYVFQGPYGPRATGLGTGKAEGIWKTPAAYIGRRPGVSGPERAAFIR-ELQEALCPN-PPPTKKITEDDVKVMLYLLEE----------------KERDLNTAARIGQSLVKQNSVLMEENNKLETMLGSAREEILHLRKQVNLRDDLLQLYSDSDDDDDEEDEEDEE-EGEEEEREGQRDQDQQHDHPYGAPKPHPKAETAH--RCPQLETLQQKLRLLEEENDHLREEASHLDNLED----EEQMLILECVEQFSEASQQMAELSEVLVLRLEGYERQQKEITQLQAEITKLQQRCQSYGAQTEKLQQMLASEK-------GIHSESLRAGSYMQDYGSRPRDR------------QEDGKSHRQRSSMPAGSVTHYGYSVPLDALPSFPETLAEELRTSLRKFITDPAYFMER-------------RDTHCREGRKKEQRAMPPP------------PAQDLKPPEDFEAPEELVPEEELGAIEEVGTAEDGQAEENEQASEETEAWEEVEPEVDETTRMNVVVSALEASG---------LGPSHLDMK---YVLQQLSNWQDAHSKRQQKQKVVPKDSPTPQQQTNMGGGILEQQPRVPTQDSQRLEEDRATHSPSAREEEGPSGAT--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P54257-1", "uniprot_id": "HAP1_HUMAN", "id": "P54257-1", "name": "Huntingtin-associated protein 1", "aln": "MRPKRLGRCCAGSRLGPGDPAALTCAPSPSASPAPEPSAQPQARGTGQRVGSRATSGSQFLSEARTGARPASEAGAKAGARRPSAFSAIQGDVRSMPDNSDAPWTRFVFQGPFGSRATGRGTGKAAGIWKTPAAYVGRRPGVSGPERAAFIR-ELEEALCPNLPPPVKKITQEDVKVMLYLLEELLPPVWESVTYGMVLQRERDLNTAARIGQSLVKQNSVLMEENSKLEALLGSAKEEILYLRHQVNLRDELLQLYSDSDEEDEDEEEEEEEKEAEEEQEEEEAEEDLQCAHPCDAPKLISQEALLHQHHCPQLEALQEKLRLLEEENHQLREEASQLDTLED----EEQMLILECVEQFSEASQQMAELSEVLVLRLENYERQQQEVARLQAQVLKLQQRCRMYGAETEKLQKQLASEKE---IQMQLQEESVWVGSQLQDLREKYMDCGGMLIEM-----QEEVKTLRQQPPVSTGSATHYPYSVPLETLPGFQETLAEELRTSLRRMISDPVYFMERNYEMPRGDTSSLRYDFRYSEDREQVRGFEAEEGLM---------LAADIMRGEDFTPAEEFVPQEELGAAKKVP-AEEGVMEEAELVSEETEGWEEVELELDEATRMNVVTSALEASG---------LGPSHLDMN---YVLQQLANWQDAHYRRQLRWKMLQKGE-CPH-------GALPAASRTSCRSSCR------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TXV1-1", "uniprot_id": "A0AB32TXV1_DANRE", "id": "A0AB32TXV1-1", "name": "", "aln": "MSVEMEEWSSLGMDESEKDSSTSHDEDDEEPEDEEQPDTEGLCRELVQVLCSERVG-----QITKAYHDIEAVTHLLEEKERDLELAARIGQSLLKKNKTLTEHNKLLDEQLESTKEEIAQLRHELSMRDDLLHFYASTEDIEHATETLLIRNDSSSSLSNYINYDFLQQKLKGLEEENFKLRTEADELTFETSNYEEQEQRLMMVCVDELTSANKQVVSLSEELARKVEDSLRQQEEISALLGQIVDLEQRYKVLSTENEELTQHLNASRESQSQLKTELKELQERYSECEDMLHEAREDIKNLRNKSLPNSTVQRYSTLAAVFPMDSLAAEIEGTFRKGLDSPAPTEYKTHPLRVFETVKVANQVSRLRSQNPSPQLPGSSPTSLRSSRISTPRTSYNEPDNISIIMEDKNSPPTHSQDHGLLESKRLGQPGTPGGQDLEEALRSLSERQESHTSERPFFEVERERKLRALLSGSSGSDGGSSGFLTPNSSTASTGTNYSGTSTHSSGTGSSRSHLPERLQIVKPLEGSATLHQWQQLAKPNLGGILLPRPGVLTKDFRELDVDLQQVYSLNDLEEDEPDLSQFPNLRHGTVVTSSGPNIPQPPPTHPSTSCQILHPSALLSSFSTSVRSRSVSACGSCEYIRTPSASTSHLYQPPTLGLLQLVSEHGISATTNPSSTSPLHREKQQGFNGSEHMGNIFSVNLVEKLRSLGLYKVVARGLVDSVRKERADPHNSPP", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : . * . *.:: . :*.:: * * . : . ..: : .: : : ..: : .: . : . .:. . .: :** : ..:*. : . ..:: : *. :. : . .: .: : *: * *:* * . .* * : *:*.: * ::.:: :. : . *. . : : : :. : . .: : : . :: . :: :. . *.: . *:. : : *. .* .. *.* *: :* . . . . :::.: . :: . :* . *:. : . *. ::: : * :. * . .:** :. :: .. * . * :. :: ** : : : . :: :*: * :.: * :. : . .*. : .: .* ::.*.* ..*** :** ::: : . . : : . . . :. ", "identical_positions": 52, "similar_positions": 194, "identity": "7.05%" }, { "cls_id": "homologset.agr.MGI:1261834", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V7U3-1", "uniprot_id": "G3V7U3_RAT", "id": "G3V7U3-1", "name": "Protein Wnt", "aln": "MLKPRGEDEAAQLAPRRARVPVAALRPAPPDVSPASARLGLACLLLLLLLTLPARVDTSWWYIGALGARVICDNIPGLVSRQRQLCQRYPDIMRSVGEGAREWIRECQHQFRHHRWNCTTLDRDHTVFGRAMLRSSREAAFVYAISSAGVVHAITRACSQGELSVCSCDPYTRGRHHDQRGDFDWGGCSDNIHYGVRFAKAFVDAKEKRLKDARALMNLHNNRCGRTAVRRFLKLECKCHGVSGSCTLRTCWRALSDFRRTGDYLRRRYDGAVQVTATQDGANFTAARQGYRHATRTDLVYFDNSPDYCVLDKAAGEKEEAETWSLVISTGSLGTAGRVCSKTSKGTDGCEIMCCGRGYDTTRVTRVTQCECKFHWCCAVRCKECRNTVDVHTCKAPKKAEWLDQT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70283-1", "uniprot_id": "WNT2B_MOUSE", "id": "O70283-1", "name": "Protein Wnt-2b", "aln": "MLKLQGEDEAAQLAPRRARVPVP--RPTAPDVSPSSARLGLACLLLLLLLTLPARVDTSWWYIGALGARVICDNIPGLVSRQRQLCQRYPDIMRSVGEGAREWIRECQHQFRHHRWNCTTLDRDHTVFGRAMLRSSREAAFVYAISSAGVVHAITRACSQGELSVCSCDPYTRGRHHDQRGDFDWGGCSDNIHYGVRFAKAFVDAKEKRLKDARALMNLHNNRCGRTAVRRFLKLECKCHGVSGSCTLRTCWRALSDFRRTGDYLRRRYDGAVQVTATQDGANFTAARQGYRHATRTDLVYFDNSPDYCVLDKAAG---------------SLGTAGRVCSKTSKGTDGCEIMCCGRGYDTTRVTRVTQCECKFHWCCAVRCKECRNTVDVHTCKAPKKAEWLDQT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q93097-1", "uniprot_id": "WNT2B_HUMAN", "id": "Q93097-1", "name": "Protein Wnt-2b", "aln": "MLRPGGAEEAAQLPLRRASAPVPVPSPAAPDGSRASARLGLACLLLLLLLTLPARVDTSWWYIGALGARVICDNIPGLVSRQRQLCQRYPDIMRSVGEGAREWIRECQHQFRHHRWNCTTLDRDHTVFGRVMLRSSREAAFVYAISSAGVVHAITRACSQGELSVCSCDPYTRGRHHDQRGDFDWGGCSDNIHYGVRFAKAFVDAKEKRLKDARALMNLHNNRCGRTAVRRFLKLECKCHGVSGSCTLRTCWRALSDFRRTGDYLRRRYDGAVQVMATQDGANFTAARQGYRRATRTDLVYFDNSPDYCVLDKAAG---------------SLGTAGRVCSKTSKGTDGCEIMCCGRGYDTTRVTRVTQCECKFHWCCAVRCKECRNTVDVHTCKAPKKAEWLDQT", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**: * :*****. *** .**. *:.** * :***********************************************************************************************.************************************************************************************************************************************************ ****************:*********************** ***************************************************************************", "identical_positions": 370, "similar_positions": 10, "identity": "91.13%" }, { "cls_id": "homologset.agr.MGI:1261835", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8NEZ2-1", "uniprot_id": "VP37A_HUMAN", "id": "Q8NEZ2-1", "name": "Vacuolar protein sorting-associated protein 37A", "aln": "MSWLFPLTKSASSSAAGSPGGLTSLQQQKQRLIESLRNSHSSIAEIQKDVEYRLPFTINNLTININILLPPQFPQEKPVISVYPPIRHHLMDKQGVYVTSPLVNNFTMHSDLGKIIQSLLDEFWKNPPVLAPTSTAFPYLYSNPSGMSPYASQGFPFLPPYPPQEANRSITSLSVADTVSSSTTSHTTAKPAAPSFGVLSNLPLPIPTVDASIPTSQNGFGYKMPDVPDAFPELSELSVSQLTDMNEQEEVLLEQFLTLPQLKQIITDKDDLVKSIEELARKNLLLEPSLEAKRQTVLDKYELLTQMKSTFEKKMQRQHELSESCSASALQARLKVAAHEAEEESDNIAEDFLEGKMEIDDFLSSFMEKRTICHCRRAKEEKLQQAIAMHSQFHAPL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8CHS8-1", "uniprot_id": "VP37A_MOUSE", "id": "Q8CHS8-1", "name": "Vacuolar protein sorting-associated protein 37A", "aln": "MSWLFPLAKSASSSAAGSPAGLTSLQQQKQRLIESLRNSHSSIAEIQKDVEYRLPFTVNNLTININILLPPQFPQEKPVISVYPPIRHHLMDSQGLYVTSPLVSNFTMHSDLGKIIQSLLDEFWKNPPVLAPTSTTFPYLYSNPGGMPPYPSQGFPFLPPYPPPEANRNITSLSVADTVSSSTTSYTAAKPVAPSFGILSSLPLPVPTTESSASVNQNGFGYKMPDIPDAFPELSELSVSQLTDMNEQEEVLLEQFLMLPQLKQIITDKEDLVKNIEELARKNLLLEHSLEGKRQTVLDKYELLLQMKSTFEKKMQRQHELSESCSASALQARLKVAAHEAEEESDNIAEDFLEGKTEIDDFLNSFKEKRTICHCRRAKEEKLHQVIAMHSQFHAPL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O77259-1", "uniprot_id": "O77259_DROME", "id": "O77259-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPTTPQDLALAHSLAQRPPTDSSEAKEQE------AGESDNLPNLCTLSLDELKQLDRDPEFFEDFIEEMSVVQYLNEELDSMMDQVEIISRENECKGIHLVELKRRLSDDFTALKNLGEKCDRLNKKYFKKSDEYAPQHIRELLQIAASNADGDCDRHVEHFLNGKTDVQTFLNTYQWSKKISTERKAKEERLGTQLSALERAGI--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.:*. *: *..::* . .*: .. .* :*:*. **:.:*.:::.: *.: : : :. :: : : :.::..:* ::*:* * :: : *.: * :: .. :: :: .: *:. :.. :: *::** :*: :.*. .*.**:** ::: **.:: .:.*. *:****:* :: .: ", "identical_positions": 39, "similar_positions": 94, "identity": "9.82%" }, { "cls_id": "homologset.agr.MGI:1261838", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q497B0-1", "uniprot_id": "NIT2_RAT", "id": "Q497B0-1", "name": "Omega-amidase NIT2", "aln": "MST-------FRLALIQLQVSS-IKSDNITRACSLVREAAKQG--ANIVSLPECFNSPYGTNYFPEYAEKIP----GESTKKLSEVAKENSIYLIGGSIPEE--DDGKLYNTCAVFGPDGNLLVKHRKIHLFDIDVPGKITFQESKTLSPGDSFSTFDTPYCRVGLGICYDMRFAELAQIYARRGCQLLVYPGAFNMTTGPAHWELLQRARAVDNQVYVATASPARDEKASYVAWGHSTVVDPWGQVLTKAGTEETILYSDIDLKKLSEIRQQIPILKQKRADLYSVESKKP-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JHW2-1", "uniprot_id": "NIT2_MOUSE", "id": "Q9JHW2-1", "name": "Omega-amidase NIT2", "aln": "MST-------FRLALIQLQVSS-IKSDNLTRACSLVREAAKQG--ANIVSLPECFNSPYGTTYFPDYAEKIP----GESTQKLSEVAKESSIYLIGGSIPEE--DAGKLYNTCSVFGPDGSLLVKHRKIHLFDIDVPGKITFQESKTLSPGDSFSTFDTPYCKVGLGICYDMRFAELAQIYAQRGCQLLVYPGAFNLTTGPAHWELLQRARAVDNQVYVATASPARDDKASYVAWGHSTVVDPWGQVLTKAGTEETILYSDIDLKKLAEIRQQIPILKQKRADLYTVESKKP-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NQR4-1", "uniprot_id": "NIT2_HUMAN", "id": "Q9NQR4-1", "name": "Omega-amidase NIT2", "aln": "MTS-------FRLALIQLQISS-IKSDNVTRACSFIREAATQG--AKIVSLPECFNSPYGAKYFPEYAEKIP----GESTQKLSEVAKECSIYLIGGSIPEE--DAGKLYNTCAVFGPDGTLLAKYRKIHLFDIDVPGKITFQESKTLSPGDSFSTFDTPYCRVGLGICYDMRFAELAQIYAQRGCQLLVYPGAFNLTTGPAHWELLQRSRAVDNQVYVATASPARDDKASYVAWGHSTVVNPWGEVLAKAGTEEAIVYSDIDLKKLAEIRQQIPVFRQKRSDLYAVEMKKP-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q4VBV9-1", "uniprot_id": "NIT2_DANRE", "id": "Q4VBV9-1", "name": "Omega-amidase NIT2", "aln": "MSK-------FRLAVVQLHVSK-IKADNLGRAQTLVKEAAGQG--AKVVVLPECFNSPYGTGFFKEYAEKIP----GESTQVLSETAKKCGIYLVGGSIPEE--DGGKLYNTCSVFGPDGTLLVTHRKIHLFDIDVPGKIRFQESETLSPGKSLSMFETPYCKVGVGICYDIRFAELAQIYAKKGCQLLVYPGAFNMTTGPAHWELLQRGRAVDNQVYVATASPARDETASYVAWGHSSVINPWGEVISKAGSEESVVYADIDLQYLADVRQQIPITKQRRNDLYSVNSVQEG", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VHE4-1", "uniprot_id": "Q9VHE4_DROME", "id": "Q9VHE4-1", "name": "omega-amidase", "aln": "MSKTSNI---MRLALLQLKGSK-DKVANVQNAVTKIEAAVKEHK-PRLITLPECFNAPYGTKYFREYSETIPD---GYTSQQLSNLARKHQVYIVGGTIPELG-ENDAIYNTCTVWSPTGDLVAKHRKMHLFDIDVKGGIRFKESETLSAGNDFTIINVDGHKIGIGICYDIRFEEMARLYRNAGCEMIIYPAAFNMTTGPLHWELLQRSRANDNQLFVVTTSPARDTSAEYVAYGHSMVVNPWAKVQQSASEGEEIVVADIDFSEVEQVRQQIPVFGQRRLDLYATERKAK-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P49954-1", "uniprot_id": "NIT3_YEAST", "id": "P49954-1", "name": "Omega-amidase NIT3", "aln": "MSASKILSQKIKVALVQLSGSSPDKMANLQRAATFIERAMKEQPDTKLVVLPECFNSPYSTDQFRKYSEVINPKEPSTSVQFLSNLANKFKIILVGGTIPELDPKTDKIYNTSIIFNEDGKLIDKHRKVHLFDVDIPNGISFHESETLSPGEKSTTIDTKYGKFGVGICYDMRFPELAMLSARKGAFAMIYPSAFNTVTGPLHWHLLARSRAVDNQVYVMLCSPARNLQSSYHAYGHSIVVDPRGKIVAEAGEGEEIIYAELDPEVIESFRQAVPLTKQRRFDVYSDVNAH--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: :::*::** *. * *: .* : :. * : ..:: ******:**.: * .*:* * . : : **: *.: : ::**:*** . . :***. ::. * *: .:**:****:*: . * *:**:***.*.. : ::. :.*:*****:** *:* : . *. ::**.*** .*** **.** *.** ***::* ****: :.* *:*** *::* .:: .*. * :: :::* . : ..** :*: *:* *:*: ", "identical_positions": 100, "similar_positions": 96, "identity": "34.13%" }, { "cls_id": "homologset.agr.MGI:1261845", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8M2BIQ8-1", "uniprot_id": "A0A8M2BIQ8_DANRE", "id": "A0A8M2BIQ8-1", "name": "", "aln": "-------------------------------------------------------------------MSASVNGVEPKPAPAVSQ-------------------NGPGSPPQTPKDVTPPELELPD-----EEPQSS-VTEATQMGIKFAKTFLLIFPIYLLGYLEFSFSWVLIGLGLVFWLKRN-------QGSRFARVNQAMAFLEQEERAVRQTIRSSELPPWVHFP--------------------------------------------------DVERVEWLNKTVQQMWPYICQFVEKIFKETIEP--AVQGAN-THLSTFTFSKIDMGDKPLRVDGVKVYTENVDKRQIIMDLQINFVGNTEIDVDIKKYYCRAG---------------------IKSIQLNGVLRVIMEPLLGDMPLVGALSVFFLKKPFLDINWT-------GLTNMLDIPGVNSLCDNVIQDIINGCLVNPNKITIPLADDALISKLRFPMPRGILRVHFLEGQDLLSKDTYMGGLIKGKSDPYGVIQIN------NQLFRSKIIKDSLNPRWNEVYEAIVYDGQGQVVFIELFDEDTDH-----DDFLGSLTMEIDEIQKQQKVD---EWFDLIGVPNGKLHVKAEWLSLHPTPDK----LDEVLSSIKADKGQANDGLS--------------------SALLLVHLDSAKNLPGVFEGQVGSGCLRERRSAGLVFCENTSALYRTMFRNPLEFNSAGLKKGAVNKAVKSGKKVTSVP-------------------------------------------------------------------------NPFVQFTVGHRSFESKTRFKTIEPVWEETFTFLIHNPKCQDLEVEVKDEKHECS---LGTITLPLSQLLKEK----------------QMTMSQR-FPLKNSGPGSTLKMKMALRILSLDKLAAS-DKPSSAQVHRAGSVRKTSNATPQRPAVSEPAKTSKTQQPAPAPRTQPTPTPSPRV-------------EPVTDRKPLEESPPHLAKSGKSMSNLAISGSNLHLNSKEQT-PSIASDISNLAATQELQKTIQQLHNGASPGFAPLGEIELT---------IRHSPQ---------------------------RNKLIVVVHKCRNLISAS-QNGSDPYVRLYLLPDKRRSGRR-------------------KTSTAKKTVNPIFDQTFEFTVS-------------------IMELPRRTLDVAVKNGGGILAKHRGLLGKVIVEFNLEDPS--KNSTQWYELSVDGFKRPSP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9QCZ0-1", "uniprot_id": "A0A8M9QCZ0_DANRE", "id": "A0A8M9QCZ0-1", "name": "", "aln": "------------------------------------------------------------MLNMTEDVMTAVRGNLSQTAVASGQK-----------------DNGQAEPTNGAIPCSSSPVELS------EEPLSC-SSELTRTWLQFAKTFVVIFPIYVLGYFEFSFSWLLIALTIFFFWKRN-------TNSKNTRLSRAMSIFDPDD-AVKQELDATELPSWVHYP--------------------------------------------------DVERVEWLNKTVNQMWPYVCQFVDKLFKETIEP--AIKESN-AHLSTFSFTKIDLGDKPLRINGVKVYSENVDKRQIIMDLQISYVGNTEIDVDVKRYYCRAG---------------------IKSIQLHGVLRVILEPLLGNMPLVGAFSLFFLKKPLLDINWT-------GLTNILDIPGLNGFSDQMIQDIISAYMVLPNRITVPLIGEVELAQLRFPMPKGVLRIYFIEAQNLEVKDTYLGGLIKGKSDPYGMLLVS------NQLFRSKTIKECLHPKWNEVYEALVYEPSGQHLEIELFDEDPDK-----DDFLGSLMIDLTELHKEQKVD---EWFDLEEVTTGKLHLRLEWLSLYSSAEK----LDQVQKSIRT-----NDNLS--------------------SALLIVNLDSASNLPSVFEGSFGCGNLKERRASGLVFCENADSLCRELFS---------------------GKKVSIDP-------------------------------------------------------------------------NPFVKLTVGQKTCTSKVRYKTSEPLWEETFPFLINNPQTQELEIEVKDSKHKCS---LGSLQVSLASLLNEV----------------DMTLNQQ-FPLQSSGPNSTLKLKMALRILSLEKEVTS-SHPSSVRVRITS--QSNTCVPPKPQATSSPTDIQPSQNP---PCTPPPDTPQ--------------------GKRGSDGSPVRLADAGRSLSSLGIGSSHKRQSHRDST-PSLASDISLPCATLELQQRLQQLQNGSGLNLYPLGEVQLT---------VRHSSQ---------------------------RNKLIVVVHACRNLIALN-KDGSDPYIRLYLLPDKSRSGRR-------------------KTSTLKKTLNPIYDQSFEFSVS-------------------MVELHRRTLDIAVKNGGGLLSKNKLLLGKTLVDLGSEDIS--KGWTHWYHLTEDGAKKLMQT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q3TZZ7-1", "uniprot_id": "ESYT2_MOUSE", "id": "Q3TZZ7-1", "name": "Extended synaptotagmin-2", "aln": "------------------------------------------------------------------------------MSSAGGE--------------------GPEAGPGRAGGRSEP-----------EAPGSALSVDLPGLLGQLARSFALLLPVYALGYLGLSFSWVLLALGLLAWCRRS-------RGLKASRLCRALALLEDEEQAVRLGVRACDLPAWVHFP--------------------------------------------------DTERAEWLNKTVKHMWPFICQFIEKLFRETIEP--AVRGAN-AHLSTFSFTKVDVGQQPLRVNGVKVYTENVDKRQIILDLQISFVGNCEIDLEIKRYFCRAG---------------------VKSIQIHGTMRVILEPLIGDMPLVGALSIFFLRKPLLEINWT-------GLTNLLDIPGLNGLSDTIILDIISNYLVLPNRITVPLVSEVQIAQLRFPIPKGVLRIHFIEAQDLQGKDTYLKGLVKGKSDPYGIIRVG------NQIFQSKVIKENLSPKWNEVYEALVYEHPGQELEIELFDEDPDK-----DDFLGSLMIDLIEVEKERLLD---EWFTLDEVPKGKLHLKLEWLTLMPDAAN----LDKVLADIRADKDQASDGLS--------------------SALLILYLDSARNLP-------------------------------------------------------SGKKINSNP-------------------------------------------------------------------------NPLVQMSVGHKAQESKIRYKTSEPVWEENFTFFIHNPRRQDLEVEVKDEQHQCS---LGSLRIPLSQLLTSD----------------NMTINQR-FQLSNSGPNSTLKMKIALRVLHLEKQERPPDYQHSAQVKRPSVSKEGRKMPIKSQMSASPGTGGANTAPS-TPVMGVDDKPAME-----------------EKPQPPEASPLGHRDLGRSSSSLLASPS--HIAAKEPT-PSIASDISLPIATQELRQRLRQLENGTTLGQSPLGQIQLT---------IRHSSQ---------------------------RNKLIVVVHSCRNLIAFS-EDGSDPYVRMYLLPDKRRSGRR-------------------KTHVSKKTLNPVFDQSFDFSVS-------------------LPEVQRRTLDVAVKNSGGFLSKDKGLLGKVLVVLASEELA--KGWTQWYDLTEDGTRPQVIT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZJ32-1", "uniprot_id": "D3ZJ32_RAT", "id": "D3ZJ32-1", "name": "Extended synaptotagmin-2", "aln": "------------------------------------------------------------------------------MSSAGGE--------------------GPEAGTGRAGGRSEP-----------EAPGSALSVDLPGLLGQLARSFALLLPVYALGYLGLSFSWVLLALGLLAWCRRS-------RGLKASRLCRALALLEDEEQAVRLGVRACDLPAWVHFP--------------------------------------------------DTERAEWLNKTVKHMWPFICQFIEKLFRETIEP--AVRGAN-AHLSTFSFTKVDVGHQPLRVNGVKVYTENVDKRQIILDLQISFVGNCEIDLEIKRYFCRAG---------------------VKSIQIHGTMRVILEPLIGDMPLVGALSIFFLRKPLLEINWT-------GLTNLLDIPGLNGLSDTIILDIISNYLVLPNRITVPLVSEVQIAQLRFPIPKGVLRIHFIEAQDLQGKDTYLKGLVKGKSDPYGIIRVG------NQIFQSKVVKENLSPKWNEVYEALVYEHPGQELEIELFDEDPDK-----DDFLGSLMIDLIEVEKERLLD---EWFTLDEVPKGKLHLKLEWLTLMPDAAN----LDKVLADIRADKDQANDGLS--------------------SALLILYLDSARNLP-------------------------------------------------------SGKKINSNP-------------------------------------------------------------------------NPLVQMSVGHKAQESKIRYKTSEPVWEENFTFFIHNPKRQDLEVEVKDEQHQCS---LGSLRIPLSQLLASD----------------NMTINQR-FQLSNSGPNSTLKMKIALRVLHLEKQERPPDYQHSAQVKRPSVSKEGRKMPIKSQMSASPGTGGTNTAPS-TPVMGVDDKPAME-----------------EKPQPPEASPLGQRDLGRSSSSLLASPS--HIAAKEPT-PSIASDISLPIATQELRQRLRQLENGTTLGQSPLGQIQLT---------IRHSSQ---------------------------RNKLIVVVHSCRNLIAFS-EDGSDPYVRMYLLPDKRRSGRR-------------------KTHVSKKTLNPVFDQSFDFSVS-------------------LPEVQRRTLDVAVKNSGGFLSKDKGLLGKVLVALASEELA--KGWTQWYDLTEDGTRPQVIT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0FGR8-1", "uniprot_id": "ESYT2_HUMAN", "id": "A0FGR8-1", "name": "Extended synaptotagmin-2", "aln": "------------------------------MTANRDAALSSHRHPGCAQRPRTPTFASSSQRRSAFGFDDGNFPGLGERSHAPGSRLGARRRAKTARGLRGHRQRGAGAGLSRPGSARAPSPPRPGGP---ENPGGVLSVELPGLLAQLARSFALLLPVYALGYLGLSFSWVLLALALLAWCRRS-------RGLKALRLCRALALLEDEERVVRLGVRACDLPAWVHFP--------------------------------------------------DTERAEWLNKTVKHMWPFICQFIEKLFRETIEP--AVRGAN-THLSTFSFTKVDVGQQPLRINGVKVYTENVDKRQIILDLQISFVGNCEIDLEIKRYFCRAG---------------------VKSIQIHGTMRVILEPLIGDMPLVGALSIFFLRKPLLEINWT-------GLTNLLDVPGLNGLSDTIILDIISNYLVLPNRITVPLVSEVQIAQLRFPVPKGVLRIHFIEAQDLQGKDTYLKGLVKGKSDPYGIIRVG------NQIFQSRVIKENLSPKWNEVYEALVYEHPGQELEIELFDEDPDK-----DDFLGSLMIDLIEVEKERLLD---EWFTLDEVPKGKLHLRLEWLTLMPNASN----LDKVLTDIKADKDQANDGLS--------------------SALLILYLDSARNLP-------------------------------------------------------SGKKISSNP-------------------------------------------------------------------------NPVVQMSVGHKAQESKIRYKTNEPVWEENFTFFIHNPKRQDLEVEVRDEQHQCS---LGNLKVPLSQLLTSE----------------DMTVSQR-FQLSNSGPNSTIKMKIALRVLHLEKRERPPDHQHSAQVKRPSVSKEGRKTSIKSHMSGSPGPGGSNTAPS-TPVIGGSDKPGME-----------------EKAQPPEAGPQGLHDLGRSSSSLLASPG--HISVKEPT-PSIASDISLPIATQELRQRLRQLENGTTLGQSPLGQIQLT---------IRHSSQ---------------------------RNKLIVVVHACRNLIAFS-EDGSDPYVRMYLLPDKRRSGRR-------------------KTHVSKKTLNPVFDQSFDFSVS-------------------LPEVQRRTLDVAVKNSGGFLSKDKGLLGKVLVALASEELA--KGWTQWYDLTEDGTRPQAMT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4K6F9-1", "uniprot_id": "A0A0B4K6F9_DROME", "id": "A0A0B4K6F9-1", "name": "", "aln": "-------------------------------------------------------MSDNSPSVPLAEFTIPPDPTETEPFVPLVEVKKMN--------------ESPVVTPTTPTGNGTPPTQTTNGNSIVATKSVSDDNSIFSVFYTLGKKVAIVGSIYLVGYMGWSVAWLIAPVILSVARDQL-------AKTSEKKRDIAKASALASEKDVILAR-IDELPAWVYFP--------------------------------------------------DVERCEWLNKILKQVWPNANHFARTLVKETIEPNVALALAN-YKMHGFRFDRIILGTIPPRIGGVKIYDKNVDRNEIIMDLDLFYASDCDINFYLG--GMKGG---------------------IKDFQIHGWVRVVMKPLIRSMPLVGGLQIFFLNNPNIDFNLV-------GVIDFMDMPGLSDLLRRIIVEQIGNVMVLPNKLPISLSEEVSAVALKMPEPEGILRIHVVEAKDLMKKDISVLG--KGKSDPYAIINVG------AQEFKTQIIDNNVNPKWDYWCEACIFTTIGHYIGFSLWDYDQTMPGVQSDDVLGRASIDIASVIKKGVVD---SWLTLEDAKHGLLHVRLQWYKLTADPND----LQQILLETQLLR---VTSMS--------------------SAVLSVFIDSARHLK--------------------------------------------------------QARSSSKP-------------------------------------------------------------------------DPYLVCSVNKQKQQTAMIMRDDSPVWEQGFTFLVSNPDNESLNIKIYDQKTGND---IGQYTYTLSTLLKQF----------------NMEVIQQPFQLQKSGPESKLYMSLSLRILKPGE----IDKDSDALEQVAALTRSSSVKTPDVAAVSPPAFKESQASSK----------------------------------RLSAESPISEED------PVAATKISPAMSASTSS-EKPISELATSVLTHRFPD------STSSPGEHGLGRMQLS---------IRYSAQ---------------------------RQKLDVTIHKIQKIPLRDPSNIPDPYVKLYLLPGRTKESKR-------------------KTSVIKDNCNPVYDASFEYLIS-------------------IAELRQTELEVTVCTQKGFLSGGSPIIGMLKIPLDDAEITTQTGLNSWFDLQPEIRHE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q03640-1", "uniprot_id": "TCB3_YEAST", "id": "Q03640-1", "name": "Tricalbin-3", "aln": "MTGIKAQVHPPPDSTLFHEEEKKKVGGNLPQKVINQQERGSDHAPSGHHQYHQLINHDANDTKTSNSVSDVSKGQKTADSNPEGKKQSSKD---------IFVASSAQKTNQLPGPNPQGSIGAVPLEGLRPKEFRSAPSRKPNKFDTSITKPGVLDDLGKLDEKDIKEKFHLDSDDKLFPWQNVGEFHASGKGSPNTKMSRVIKAYILENFYNDWYCNIATVLGTCFFSWLFAYIGFSWWSMIFIFLGTATVYNAEYTRFNRNIRDDLKRVTVEETLSDRVESTTWLNSFLSKFWVIYMPVLSQQVKDNVNPQLAGVAPG-YGIDALAIDEFTLGSKAPTIKGIKSYTKTG-KNTVEMDWSFAFTPSDVSDMTATEAREKINPKISLGVTLGKSFVSKTMPILVEDINVAGKMRIKVE-FGKAFPNIKIVSLQLLEPPLIDFALKPIGGDTLGLDVMSFLPGLKSFVKNIINSNIGPMLFPPNHLDINVEDIMAAQSK---EAIGVLAVTIASADSLKGSD-----FITNTVDPYIVMTTEDAVPGTDEEVRTSIKSNVKNPRWNET-KYLLLNTLEQKLNLKCFDFNDVR----KDTVIGDLQLDLADLLQNPVLDNQTAELRSGTKSKGILHYSLHWFPVKEDKSEEK-AVERAEAKAKGKKEDENEDTTEKEEDENEESSQTDVGIAKITLQKVKYLDTTSSMTGSLSPCAELFIDGQKVKSYRTLRRINEPSWNETIEVLVPSKSNSKFVLKIFDDRMNGKALICEYSSSLDDIMTTLDTAQEFVKGSPQGDIYLDVSWKSIEMTGAFAAANSVSEPIGCIKLDVKDAIIKGDLSGVGDVDPYYTVSLNRRVLYKSIYHSDTDHPIFDNSTYVPIFSPNQILTLEFHDYQKIGKDRFIGSVQIPTSNVFKKDPKSGKYVGNNGKEEISKLKLKDHEHKVTESIVNVSTTFIPINLVYSPEELVNVEKLEKELKEKKKKFEATQEENEQEMEKNPKEWEVAEIEDPFDSDEKKINRKAKLSLNELIKQKSGILSMQILEGTLSPSSAYLEILADDISYPVFICMKPSQGKLNSEMA-NIFIRDLNYSKLHFRVSKKHIAKDSDDVISETSYSTLKLLKQAYEEPMWLNFNGS---------------------------KMKVRFLYTPTSVKLPSSESVEDTGYLNIKLISGHGLKSADRNGYSDPFVHIFVNDKKVFKSNIKKKTLDPVWNEDAKIPILSRSKNQVIFNVLDWDRAGDNDDLGQASLDVSSLEVGKTYNWNLNLNTQGSIKLQGSFNP--EYIKPSFDIVKGGITDKPMKIASGAAHATVGIAGTGIGAATGVATGGLKKGGHLLKSLGGNPMKRSKSSNGNESNGAKKSSEKKSFDRRSPSNLNSTSVTPRASLDYDPSVPNTSYAPVQSASPVVKPTDNTSSSSNKKDTPSSNSRGHSRASSFARTLAPHGTYNGFITVVAAENVAKHVQIKISLTQGGRLKHIYKTKSQKANNDGVAVFDEECSFKASPEANLVLGAISHQRLSRDKDLGIAQINLGDPQIQQDGQISVKLGDGHLIVKINYGKDKNGQVPPVPEVPQEYTQ", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q12466-1", "uniprot_id": "TCB1_YEAST", "id": "Q12466-1", "name": "Tricalbin-1", "aln": "----------------------------------------MAKEDTGVTAPKKPETAQVANINGIDKLEPPKTKEETESSKSVSSEK----------------AAHASDESFKRSIHEASYVGWKQIGGWEDKDELTLDDELMDMTRETFLDNIIPDSLYGDWYHSVAIFFIGGVASFALGHYKFS--------MGSAFFVIVITSLLYRTSAKKYRGSIRELVQKEFTVQKVEN---------------------------------------------DYESLEWLNAFLDKYWPILEPSVSQLIVQQANEQMATNEAIPKFITQLWIDELTLGVKPPRVDLVKTF-QNTASDVVVMDWGISFTPHDLCDMSAKQVRNYVNELAVVKAKIFG----ITIPVSVSDIAFKAHARVKFK-LMTPFPHVETVNIQLLKVPDFDFVATLFG-RSIFNWEILAIPGLMTLIQKMAKKYMGPILLPPFSLQLNIPQLLSGSNLS----IGILEITVKNAKGLKRTSS----ILNESIDPYLSFEFN-----DISIAKTRTVRDTLNPVWDET-LYVLLNSFTDPLTISVYDKRAKLK----DKVLGRIQYNLNTLHDKTTQRNLKAQFLRNSKPVGELTFDLRFFPTLEEKKLPDGSVEELPDLNTGIAKVVVEEGSRFAEEEQ-----------KVTAYVEVYLNAKLVLTTGKATDTGTLKWNSDYEAVIADRRKTRYKFVVKDGKGEEIGSTIQTLNDLIDRSQVNKNLIPLKNQKGDIKITTYWRPVRLEIGS---------------------NSVAYTPPIGAIRVFIEKANDLRNLEKFGTIDPYCKVLVNGLSKGRTDFKSQTLNPVWNQVIYVAVTSPNQRITLQCMDVETVNKDRSLGEFNVNVQDLFKKDENDKYEETIDEKAKVGRLVMPKKKPKGTITYYTSFYPALPVLTLEEIQDLDKVNKKKKALELRKSAIDEKKISKEDKAKFDQEWNEVKELEDMYSNRQKLDLPELLQYN-------QGVLAVTVLNGELPDSGLYVQAFFDDNGHPRFVSPRIPSRIVKNGWSGDVIIKELDKSITTFRVAKNKNYNRVEKCVCEVELPTQELVKNCYYKPSILHLSGEGSAKLMLQISWFPIDTKQLPANDLITNSGDLTIMSRSAENLIASDLNGYSDPYLKYYINNEEDCAYKT---------------------KVVKKTLNPKWNDEGTIQINNRLNDVLRIKVMDWDSTSADDTIGTAEIPLNKVKVEGTTELDVPVEGLENAGQDGGMLHLAFSFKPRYTISVSKREKKVGDIASKG-------LGTGLKAGTTVIGGGVGAIGKIKKGVFGGLGSLTNHKKNHEMGEEETKF----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : : : . . : . * *** :.: * . : : * . : : : .. :* . : :* : :. : :* : :. :. . :..: . . *: .: : :* : ..: :*. * ::: : :**: : : . :. :. * : : : *:* : . ....* .. . . *** : . :: : * *: : . : :. :* * .:* :: : .: : * * .: ::. : : ::: : :* :. : :. . : : :: * : . :* :: . : : .: : : . . : . . : :: .. . :* :. . . .: . . . *:. : . *.. :* :: : : : : : . : : ", "identical_positions": 36, "similar_positions": 172, "identity": "2.25%" }, { "cls_id": "homologset.agr.MGI:1261847", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5XW39-1", "uniprot_id": "A0A8I5XW39_RAT", "id": "A0A8I5XW39-1", "name": "Serine/threonine-protein kinase VRK1", "aln": "MPRV---KAAQAGRQ-GPAKR------RLAEQFAAGEIITDMSKKEWKLGLPIGQGGFGCIYLADTNSSKPVGSDAPCVVKVEPSDNGPLFTELKFYQRAAKPEQIQKWIHTHKLKYLGVPKYWGSGLHDKNGKSYRFMIMDRFGSDLQKIYEANAKRFSRKTVLQLSLRILDILEYIHEHEYVHGDIKASNLLLSYKN--PDQVYLVDYGLAYRYCPDGVHKEYKEDPKRCHDGTLEFTSIDAHNGVAPSRRGDLEILGYCMIQWLSGCLPWEDN--LKDPNYVRQSKIRYRDNVAALMEKCFPERNKPGEIAKYMETVKLLDYTEKPLYQNLRDILLQGLKAIGSKDDGKLDFSAVENGSVNTKPASKKRKKGAVEEESSVCAVEESPVCAVEESPVCAVEDMECADTQAQEAIQTRSEEPQGAIYGSTSQPEAGCSSSDSSR--------------------TRKKAQQ------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80X41-1", "uniprot_id": "VRK1_MOUSE", "id": "Q80X41-1", "name": "Serine/threonine-protein kinase VRK1", "aln": "MPRV---KAAQAGRP-GPAKR------RLAEQFAAGEVLTDMSRKEWKLGLPIGQGGFGCIYLADTNSSKPVGSDAPCVVKVEPSDNGPLFTELKFYQRAAKPEQIQKWIRTHKLKYLGVPKYWGSGLHDKNGKSYRFMIMDRFGSDLQKIYEANAKRFSRKTVLQLSLRILDILEYIHEHEYVHGDIKASNLLLSHKN--PDQVYLVDYGLAYRYCPDGVHKEYKEDPKRCHDGTLEFTSIDAHKGVAPSRRGDLEILGYCMIQWLSGCLPWEDN--LKDPNYVRDSKIRYRDNVAALMEKCFPEKNKPGEIAKYMESVKLLEYTEKPLYQNLRDILLQGLKAIGSKDDGKLDFSAVENGSVKTRPASKKRKK------------------EAEESAVCAVEDMECSDTQVQEAAQTRSVESQGAIHGSMSQPAAGCSSSDSSRRQQHLGLEQDMLRLDRRGSRTRKKAQK------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99986-1", "uniprot_id": "VRK1_HUMAN", "id": "Q99986-1", "name": "Serine/threonine-protein kinase VRK1", "aln": "MPRV---KAAQAGRQ-SSAKR------HLAEQFAVGEIITDMAKKEWKVGLPIGQGGFGCIYLADMNSSESVGSDAPCVVKVEPSDNGPLFTELKFYQRAAKPEQIQKWIRTRKLKYLGVPKYWGSGLHDKNGKSYRFMIMDRFGSDLQKIYEANAKRFSRKTVLQLSLRILDILEYIHEHEYVHGDIKASNLLLNYKN--PDQVYLVDYGLAYRYCPEGVHKEYKEDPKRCHDGTIEFTSIDAHNGVAPSRRGDLEILGYCMIQWLTGHLPWEDN--LKDPKYVRDSKIRYRENIASLMDKCFPEKNKPGEIAKYMETVKLLDYTEKPLYENLRDILLQGLKAIGSKDDGKLDLSVVENGGLKAKTITKKRKK------------------EIEESKEPGVEDTEWSNTQTEEAIQTRSR--------------------------------------------TRKRVQK------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZUS1-1", "uniprot_id": "VRK1_DANRE", "id": "Q7ZUS1-1", "name": "Serine/threonine-protein kinase VRK1", "aln": "MPPK---KADGVKKARAPAKR------KLAEEFPSGEVLTDNAKKKWKLGSAVGQGGFGLLYLANEDSSGPVTADAPYVIKVEPSDNGPLFSELKFYMRAAKPDLIGAWMKSKKMEYLGVPKYWGSGFHEKNGKRYRFMVMDRFGTDLQKLFEGNGKKFSRKLVLQLGLRLLDILEYIHDHEYVHADIKASNLLLSYTN--PNQVFLVDYGLAYRYAPEGVPKEYKEDPKRCHDGTIEFTSIDAHKGVSPSRRADLEIMGYCMIQWLCSRLPWEDK--LQDPLYVRDSKLRCRDNIDEFLKSCFASGNIPAEMGKFMQEVKVLGYTDRPDYDKLRGILQQGLKSIGSTDDKKLDFGVATNSTSLPSVKTPKRKK-------------------AEEKGQ-SADETDSTPAKKRRAPQKKEVNGAKKTASPAKRPVKKETQASSEPAVK----------------KSRGRPKKNS----------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7KRY6-1", "uniprot_id": "NHK1_DROME", "id": "Q7KRY6-1", "name": "Nucleosomal histone kinase 1", "aln": "MPRVAKPKAAAPAKKVVSAKKAKSKLYKMPEKVKEGTVFTDLAKGQWRIGPSIGVGGFGEIYAACKVGEK----NYDAVVKCEPHGNGPLFVEMHFYLRNAKLEDIKQFMQKHGLKSLGMPYILANGSVEVNGEKHRFIVMPRYGSDLTKFLEQNGKRLPEGTVYRLAIQMLDVYQYMHSNGYVHADLKAANILLGLEKGGAAQAYLVDFGLASHFVTG----DFKPDPKKMHNGTIEYTSRDAHLGV-PTRRADLEILGYNLIEWLGAELPWVTQKLLAVPPKVQKAKEAFMDNIGESLKTLFPKG-VPPPIGDFMKYVSKLTHNQEPDYDKCRSWFSSALKQLKIPNNGDLDFKMKPQTSSNNNLSPPGTSKAATARKAKKIDSPVLN-SSLDEKISASEDDEEEEEKSHRKKTAKKVTPSARNAKVSPLKRVADSSPPSQKRVKTEPKSTPRERATPKASPKPRSTPKASPKPQTPTAARLRTPNAKINFSPSISLRGRPGGKTVINDDLTPQPRSKKTYEFNFELDVSMDANVIVNVKRKKKADQDKATAVDSRTPSSRSALASSSKEEASPVTRVNLRKVNGHGDSSTPGRSPRTPAVTVRKYQG", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** ** : .**: ::.*:. * ::** :: :*::* .:* **** :* * .. : *:* ** .***** *::** * ** : * :::.: :: **:* ..* : **: :**::* *:*:** *: * *.*::.. * :*.:::**: :*:*.: ***.*:**:*:**. : . *.:***:*** :: . ::* ***: *:**:*:** *** ** *:**.****:** :*:** . *** : * * *:.:* :*: :.. *.. * :..:*: *. * :.:.* *:: *. : ..** : :: .**: : . .* :*. . :: : . .. .: .* : ", "identical_positions": 124, "similar_positions": 132, "identity": "20.33%" }, { "cls_id": "homologset.agr.MGI:1261849", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZYT3-1", "uniprot_id": "D3ZYT3_RAT", "id": "D3ZYT3-1", "name": "", "aln": "MRPVCTVVVDGLPSESTSSSYPGPVSVSDMSLLHALGPVQTWLGQELEKCGIDAMIYSRYILSLLLHDSYDYDLQEQENDILG-WEKGAYKKWGRSKKKCSDLTLEEMKKQAAVQCLRSASDESSGIETLVEELCCRLKDLQSEQEEKIHKKLEGSPSPEAELSPTAKDQVEMYYEAFPPLSEKPVCLQEIMTVWNKSKPCSYSSSSSSSTVPPASTDPSSPKDCNSESEAVRERSSAASILTHEKAQSRSRHE-ENKLSHSTIEEKPALYKKQIRHKPEGKIRPRSWSSGSSEAGSSSSGNQGELKASMKYVKVRHKAREIRNKKGRNGQSRQSLKHCGKAERGVHAGSSSSSSSSSSSNGSIRQLCKRGKRPAKETGRSDSGNTAVKDLYVESRSNKEYKEEPLWYTEPIAEYFVPLSRKSKLETTYRNREDTSALTAEAVEDLSDSVRGLCISNSNIHRTYLAAGTFIDGHFVEMPAVINEDIDLAGTSLCSLPEDNKYLDDIHLSELTHFYEVDIDQSMLDPGASETMQGESRILNMIRQKSKENTDFEAECCIVLDGMELQGERAIWTDSTSPVGAEGFFLQDLGNLAQFWECCSSSSGDADGESFGGDSPVRLSPILDSTILSSHMLAGNQEPFSNINEGSGINSCFSVFEVQCSNSVLPFSFETLNLGSEHTDSSANMLGKTQSRLLIWTKNSAFEENEHCSNLSTRTCSPWSHSEEARSDNETLNLQFEESTQFTAEDINYVVPRVSSDFVDEELLDFLQDETCQQNSRTLGEIPTLVFKKRSKLESVCGIQLEQKAESKNFETTQACGESSPHGDGYSSGVIKDIWTKMVGRSSVAAAETERAGEELFSTDVSNYCCCLDTEAKMETLQEPSRAVQRSEYHLWEGQKENVEKRAFVSSELSKVDGGDYTTPSKPWDVAQDKENTFILGGVYGELKTFNSDGEWAVVPPGHTKGSLLQCAASDVVTIAGTDVFMTPGNSFAPGHRQLWKPFVSFEQNDMPKSGENGLNKGFSFIFHEDLLGACSNFQVEDPGLEYSFSSFDLSNPFSQVLHVECSFEPEGIASFSPSFKPKSILCSDSDSEVFHPRICGVDRTQYRAIRISPRTHFRPISASELSPAGGSESEFESEKDEANIPIPSQVDVFEDPQADLKPLEEDAEKEGHYYGKLELESGKFLPRLKKSGMEKSAQTSLDSQEEAAGILPVGKQSQCLECNFNESLGINLESSTANCKIMTQCEEEMNGFCSCKAGCQFPACEDNPVSSGQLEEFPVLNTDVQEVTRNQEKQSWWEKALYSPLFPTSECEECYTNAKGENGIEEYPDAKETPSREERLLDFNRVSSVYEARCTGERGSETKPNGLPGKMCSSASSDAGDTGSEAGGEWVGPSREDLFSRTHL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80U59-1", "uniprot_id": "K0232_MOUSE", "id": "Q80U59-1", "name": "Uncharacterized protein KIAA0232", "aln": "MRPVCTVVVDGLPSESTSSSYPGPVSVSDMSLLHALGPVQTWLGQELEKCGIDAMIYSRYILSLLLHDSYDYDLQEQENDILS-WEKGAYKKWGRSKKKCSDLTLEEMKKQAAVQCLRSASDESSGIETLVEELCCRLKDLQSEQEEKIHKKLEGSPSPEEELSPTAKDQVEMYYEAFPPLSEKPVCLQEIMTVWNKSKPCSYSSSSSSSTVPPASTDTSSPKDCNSESEAVRERSSVASVPMHEKAQSRSRHEKESKLSSSTIEEKPAFYKRQIRHKPEGKTRPRSWSSGSSEAGSSSSGNQGELKASMKYVKVRHKAREIRNRKGRNGQNRHSLKHCGKAERGVHAGSGGSSSSSS--NGSIRQLCKRGKRPAKETGRSDSGNTAVKDLYVDSRNNKEYKEEPLWYTEPIAEYFVPLSRKSKLETTYRNREDTSTLTAEAVEDLSDSVRGLCISNSNIHRTYLAAGTFIDGHFVEMPAVINEDIDLAGTSLCSLPEDNKYLDDIHLSELTHFYEVDIDQSMLDPGASETMQGESRILNMIRQKSKENTDFEAECCIVLDGMELQGERAIWTDSTSSVGAEGFFLQDLGNLAQFWECCSSSSGDADGESFGGDSPVRLSPILDSTMLSSHILAGNQEPFSNINEGSGINSCFSVFEVQCSNSVLPFSFETLNLGSEHADSSANMLGKTQSRLLIWTKNSAFEENEHCSNLSTRTCSPWSHSEEARSDNETLNIQFEESTQFTAEDINYVVPRVSSDFVDEELLDFLQDETCQQNSRTLGEIPTLVFKKRSKLESVCGIQLEQKAESKNFETTHACSESSPHGDGYSSGVIKDIWTKMVGRSSVAAVETERTGEELFSTDVNNYCCCLDTEAKMEALQEPSRAVQRSEYHLWEGQKENMEKRAFVSSELSKVDGGDYTTPSKPWDVAQDKENTFILGGVYGELKTFNSDGEWAVVPPGHTKGSLLQCAASDVVTIAGTDVFMTPGNSFAPGHRQLWKPFVSFEQSDMPKRGENGVNKGFSFIFHEDLLGACSNFQVEDPGLEYSLSSFDLSNPFSQVLHVECSFEPEGIASFSPSFKPKSILCSDSDSEVFHPRICGVERTQYRAIRISPRTHFRPISASELSPGGGSESEFESEKDEASVPIPSHVDVFEDPQADLKPLEEDAEKEGHYYGKLELESGKFLPRLKKSGMEKSAQTSLDSQEEATGILP--KQNQCLECNFNESLEINLESSAANCKIMTQCEEEMSEFCSCKAGCQFPACEDNPVSSGQLEEFPVLNTDVQEVTRNQEKQSWWEKALYSPLFPTSECEECYTNAKGENGIEECPDAKETPSREERLLDFNRVSSVYEARCTGERGSETKPNGLHRKMCSSASSDTGDTGSEAGGEWVGPSREELFSRTHL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92628-1", "uniprot_id": "K0232_HUMAN", "id": "Q92628-1", "name": "Uncharacterized protein KIAA0232", "aln": "MYPICTVVVDGLPSESSSSSYPGPVSVSEMSLLHALGPVQTWLGQELEKCGIDAMIYTRYVLSLLLHDSYDYDLQEQENDIFLGWEKGAYKKWGKSKKKCSDLTLEEMKKQAAVQCLRSASDESSGIETLVEELCSRLKDLQSKQEEKIHKKLEGSPSPEAELSPPAKDQVEMYYEAFPPLSEKPVCLQEIMTVWNKSKVCSYSSSSSSSTAPPASTDTSSPKDCNSESEVTKERSSEVPTTVHEKTQSKSKNEKENKFSNGTIEEKPALYKKQIRHKPEGKIRPRSWSSGSSEAGSSSSGNQGELKASMKYVKVRHKAREIRNKKGRNGQSRLSLKHGEKAERNIHTGS--SSSSSS---GSVKQLCKRGKRPLKEIGRKDPGSTEGKDLYMENRKDTEYKEEPLWYTEPIAEYFVPLSRKSKLETTYRNRQDTSDLTSEAVEELSESVHGLCISNNNLHKTYLAAGTFIDGHFVEMPAVINEDIDLTGTSLCSLPEDNKYLDDIHLSELTHFYEVDIDQSMLDPGASETMQGESRILNMIRQKSKENTDFEAECCIVLDGMELQGERAIWTDSTSSVGAEGLFLQDLGNLAQFWECCSSSSGDADGESFGGDSPVRLSPILDSTVLNSHLLAGNQELFSDINEGSGINSCFSVFEVQCSNSVLPFSFETLNLGNENTDSSANMLGKTQSRLLIWTKNSAFEENEHCSNLSTRTCSPWSHSEETRSDNETLNIQFEESTQFNAEDINYVVPRVSSNYVDEELLDFLQDETCQQNSRTLGEIPTLVFKKTSKLESVCGIQLEQKTENKNFETTQVCNES-PHGDGYSSGVIKDIWTKMADTNSVATVEIERTDAELFSADVNNYCCCLDAEAELETLQEPDKAVRRSEYHLWEGQKESLEKRAFASSELSNVDGGDYTTPSKPWDVAQDKENTFILGGVYGELKTFNSDGEWAVVPPSHTKGSLLQCAASDVVTIAGTDVFMTPGNSFAPGHRQLWKPFVSFEQNDQPKSGENGLNKGFSFIFHEDLLGACGNFQVEDPGLEYSFSSFDLSNPFSQVLHVECSFEPEGIASFSPSFKPKSILCSDSDSEVFHPRICGVDRTQYRAIRISPRTHFRPISASELSPGGGSESEFESEKDEANIPIPSQVDIFEDPQADLKPLEEDAEKEGHYYGKSELESGKFLPRLKKSGMEKSAQTSLDSQEESTGILSVGKQNQCLECSMNESLEIDLESSEANCKIMAQCEEEINNFCGCKAGCQFPAYEDNPVSSGQLEEFPVLNTDIQGMNRSQEKQTWWEKALYSPLFPASECEECYTNAKGESGLEEYPDAKETPSNEERLLDFNRVSSVYEARCTGERDSGAKSDGFRGKMCSSASSTSEETGSEGGGEWVGPSEEELFSRTHL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* *:************:***********:****************************:**:********************: **********:****************************************.*******:**************** ****.********************************* ***********.******.***********..:**** .. ***:**:*::* *.*:* .*******:**:********* *****************************************:******.* **** ****.:*:** ****** **::********* ** **.*.*.* ****::.*.:.*********************************:*** **:****:**:**:******.*:*:**************************:****************************************************************************************.*****:******************************************:*.**:****** **:*********************************.*::*********************************************:********:********.*************::******************************* **************:*.******:.*.** ******************.. .***:.* **:. ****:**.*******:**::*:****.:**:************.:*****.*****:**********************************************.**********************************************.* ** ****:****************.************:*****************************************************:*************************.**************.:****:**:************************ *****************************::***. **.*****.:**** *:**** ******:*****:. **.********* *******************:* :.*.****:************:*************.*:** ********.**********************.* :*.:*: ******** : :****.********.*:*******", "identical_positions": 1223, "similar_positions": 131, "identity": "87.29%" }, { "cls_id": "homologset.agr.MGI:1261855", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B0K020-1", "uniprot_id": "CISD1_RAT", "id": "B0K020-1", "name": "CDGSH iron-sulfur domain-containing protein 1", "aln": "----------------MGLSSDSPVR-------VEWIAAVTFAAGTAALGYLAYKKFYAKE-----SRTKAMVNLQIQKDNPKVVHAFDMEDLGDKAVYCRCWRSKKFPFCDGAHIKHNEETGDNVGPLIIKKKET", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91WS0-1", "uniprot_id": "CISD1_MOUSE", "id": "Q91WS0-1", "name": "CDGSH iron-sulfur domain-containing protein 1", "aln": "----------------MGLSSNSAVR-------VEWIAAVTFAAGTAALGYLAYKKFYAKE-----NRTKAMVNLQIQKDNPKVVHAFDMEDLGDKAVYCRCWRSKKFPFCDGAHIKHNEETGDNVGPLIIKKKET", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NZ45-1", "uniprot_id": "CISD1_HUMAN", "id": "Q9NZ45-1", "name": "CDGSH iron-sulfur domain-containing protein 1", "aln": "----------------MSLTSSSSVR-------VEWIAAVTIAAGTAAIGYLAYKRFYVKD-----HRNKAMINLHIQKDNPKIVHAFDMEDLGDKAVYCRCWRSKKFPFCDGAHTKHNEETGDNVGPLIIKKKET", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VAM6-1", "uniprot_id": "CISD2_DROME", "id": "Q9VAM6-1", "name": "CDGSH iron-sulfur domain protein", "aln": "MEPISHLVKSSLPNYLSSLPVPDSIGGWFKLSFKDWLALIPPTVVVAGLGYTAYLAYCPAARASCAAKNSGRCNNHIRKNEPKVVDMIDVEDIAEKAAFCRCWKTKNWPYCDGSHGEHNKQTGDNVGPIVIKK---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .*. ..: :*:* :. :. .*.:** ** : :... * :*:*::**:*. :*:**:.:**.:****::*::*:***:* :**::*******::*** ", "identical_positions": 41, "similar_positions": 43, "identity": "30.15%" }, { "cls_id": "homologset.agr.MGI:1261856", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7TP65-1", "uniprot_id": "ANKL2_RAT", "id": "Q7TP65-1", "name": "Ankyrin repeat and LEM domain-containing protein 2", "aln": "MLWQRLAVVEWAALAWELLGASVLLIAVRWLVRRLENLSRDPNRCGTLSSLPGASAAVSAQPGEVMTMDAMLAR--------LKLLNPDDLRQEVMKAGLKCGPITSTTRFIFEKKLAQALLEQGGLLTSSLPKHSEVTGTAFIHGT-SRTPAFVDRKQTQQACLSEDRDFGYSVGLNPPEEEAVTSSVHPIPFSAST------RNDNHKAGVTTAKEPLLYYGVCPVYEDGLVRHERIHVYEDKKEALQAVKLIKGSRFKAFPTREDAEKFARGICDYLPSPSKNMSLLSPVKAMPLCSNDGPKADGLCLAE------SETVNKERANSYKNPRTQDLTAKLRKAVERGEEHTFSDLIWSNPRYLIGS---GDNPTIVQEGCRYNVMHVAAKENQASVCQLTLETLEN-------PEFMRLMYPDDNMDMLQKRILYI---VDLYLNTPD-KVGFDTPLHFACKFGNVDVVNVLSSHPLIVKNPRNKYGKTPEDVICERSKNKSVELRERIREYLMGHYYVPLLRAEDTS-PVIGELWSSDQKAEASS-----------ADHCRSSPRDPVMTLRAFVGPLSPSKAEDFRKLWKTPPRKKAGLFHS------IRKSDPERGIERVGRELAHELGYPWVEYWEFLGCFVDLSSQEGLQRLEEYLIQKELNQKAQHEIGE----------------EEGCLQDRTSDFGSGKKYSNSISVGAFLDGGDDISLEEVK----NQQNTVPSQSQPSVDKFQNSKSGSPSLGQKADPGEAAVGFYPDNSRNGFCYPLNS-RTADGRE--------------TEATNGEEALP------------PPVSILTQEFDKLNLQSLGDNLFETPNKNRELEDKILASSKGVVESG-LASPAAIARLENKQVRTNSEVSEAMAEMSLGPNSPQLGVQAGLEPG----------------------------------------------------FSSATADPTKRLFLSGEEPSKLDRDVLAALECAIIDPGLYPAVHRWKSTVMGYSPSDRQSWPSPALKGKFTTELVDLDCCHSCS-GRSSPAGSSPSKPGHTTFSSGLHSPGRYSPAHGRHFQRVACMARLAAL--------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6P1H6-1", "uniprot_id": "ANKL2_MOUSE", "id": "Q6P1H6-1", "name": "Ankyrin repeat and LEM domain-containing protein 2", "aln": "MLWQRLAVVEWAALAWELLGASVLFIAVRWLVRRLEKRPRDLNRCGTLSSPPSASEAVAAQPGEVT-MDAMMAR--------LKLLNPDDLRKEVMKAGLKCGPITSTTRFIFEKKLAQALLEQGGLLTSSLPKPSAVTAMAFIQGT-SRTPPSVDGKQTQQACFSEDRDFGYSVGLNPPEEEAVASSVHPVPFSAST------RNDNHKAGVTAPKEPLVYYGVCPVYEDGPVRHERIHVYEDKKEALQAAKLIKGSRFKAFRTREDAEKFARGICDYLPSPNKTTPLLSPVKAVPLGGSDGLKADGLCLAE------SETVNKERANSYKNPRTQDLTAKLRKAVENGEEHTFSDLIWSNPRYLIGS---GDNPTIVQEGCRYNVMHVAAKENQASMCQLTLETLEN-------PEFMRLMYPDDNMDMLQKRILYV---VDLYLNTPD-KVGFDTPLHFACKFGNVDVVNVLSSHPLIVKNRKNKYGKTPEEVICERSQNKSPALKERIREYLMGHYYVPLLRAEDTS-PVIGELWSSDQKAEASN-----------TAHCRSSPRDPVMTLRAFVGPLSPSKAEDFRKLWKTPPRKKAGFFHS------IRKSDPERGIERVGRELAHELGYPWVEYWEFLGCFVDLSSQEGLQRLEEYLIQKELSKKAQQEIRE----------------NEGCLQDRTSDFGSGKKYSNSISVGAFLDGDDDSSLEEIK----NQQNTVPSQSQPTTDKFQTSKSGSLPLGQKVDPGETSVGTYPDKGRNGFCHPLNH-RTADGRG--------------LEATNGEEALP------------PPVSVLTQELNKLNLQSLGDSLHETPDKNGKLEDEVLPSRKGAADSDLLASPPAIASLGKKQVRTNTEVSEAMAEMSLGPKSPQLGVQAGLEPI----------------------------------------------------LSSATVDSTKRLFLSGEEPSKLDRDVLAALECANIDPGLYPAIHRWKSTVMCYSPSDRQSWPSPALKGKFTTELVDLDCSHSCS-GRCSPAGSSPSKPGHTSSSSGLHSPGRYSPAHGRHFQRVAHVARLAAL--------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86XL3-1", "uniprot_id": "ANKL2_HUMAN", "id": "Q86XL3-1", "name": "Ankyrin repeat and LEM domain-containing protein 2", "aln": "MLWPRLAAAEWAALAWELLGASVLLIAVRWLVRRLGPRPGGLGRSGTPVPPPSAAAAPAS--GEMT-MDALLAR--------LKLLNPDDLREEIVKAGLKCGPITSTTRFIFEKKLAQALLEQGGRLSSFYHHEAGVT--ALSQDP-QRILKPAEGNPTDQAGFSEDRDFGYSVGLNPPEEEAVTSKTCSVPPSD---------TDTYRAGATASKEPPLYYGVCPVYEDVPARNERIYVYENKKEALQAVKMIKGSRFKAFSTREDAEKFARGICDYFPSPSKTSLPLSPVKTAPLFSNDRLK-DGLCLSE------SETVNKERANSYKNPRTQDLTAKLRKAVEKGEEDTFSDLIWSNPRYLIGS---GDNPTIVQEGCRYNVMHVAAKENQASICQLTLDVLEN-------PDFMRLMYPDDDEAMLQKRIRYV---VDLYLNTPD-KMGYDTPLHFACKFGNADVVNVLSSHHLIVKNSRNKYDKTPEDVICERSKNKSVELKERIREYLKGHYYVPLLRAEETSSPVIGELWSPDQTAEASH-----------VSRYGGSPRDPVLTLRAFAGPLSPAKAEDFRKLWKTPPREKAGFLHH------VKKSDPERGFERVGRELAHELGYPWVEYWEFLGCFVDLSSQEGLQRLEEYLTQQEIGKKAQQETGE----------------REASCRDKATTSGS-----NSISVRAFLD-EDDMSLEEIK----NRQNAARNNSPPTVGAFGHTRCSAFPLEQEADLIEAAEPGGPHSSRNGLCHPLNHSRTLAGKR--------------PKAPRGEEAHL------------PPVSDLTVEFDKLNLQNIGRSVSKTPDESTKTKDQILTSRINAVERD-LLEPSPADQLGNGHRRTESEMSARIAKMSLSPSSPRHEDQL-----------------------------------------------------------EVTREPARRLFLFGEEPSKLDQDVLAALECADVDPHQFPAVHRWKSAVLCYSPSDRQSWPSPAVKGRFKSQLPDLSGPHSYSPGRNSVAGSNPAKP-------GLGSPGRYSPVHGSQLRRMARLAELAAL--------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8MQX9-1", "uniprot_id": "ANKL2_DROME", "id": "Q8MQX9-1", "name": "Ankyrin repeat and LEM domain-containing protein 2 homolog", "aln": "-MSTYFGVYIPTSKAGCFEGSVSQCIGSIAAVNIKPSNPASGSASVASGSPSGSAASVQTGNADDGSAATKYEDPDYPPDSPLWLIFTEKSKALDILRHYKEARLREFPNLEQAESYVQFGFESIEALKRFCKAKPESKPIPIISGSGYKSSPTSTDNSCSSSPTGNGSGFIIPLGSNSSMSNLLLSDSPTSSPSSSSNVIANGRQQQMQQQQQQQPQQPDVSGEGPPFRAPTKQELVEFRKQIEGGHIDRVKRIIWENPRFLISSGDTPTSLKEGCRYNAMHICAQVNKARIAQLLLKTISDREFTQLYVGKKGSGKMCAALNISLLDYYLNMPDKGRGETPLHFAAKNGHVAMVEVLVSYPECKSLRNHEGKEPKEIICLRNANATHVTIKKLELLLYDPHFVPVLRSQSNTLPPKVGQPFSPKDPPNLQHKADDYEGLSVDLAISALAGPMSREKAMNFYRRWKTPPRVSNNVMSPLAGSPFSSPVKVTPSKSIFDRSAGNSSPVHSGRRVLFS-----PLAEATSSPKPTKNVPNGTNECEHNNNNVKPVYPLEFPATPIRKMKPDLFMAYRNNNSFDSPSLADDSQILDMSLSRSLNASLNDSFRERHIKNTDIEKGLEVVGRQLARQEQLEWREYWDFLDSFLDIGTTEGLARLEAYFLEKTEQQADKSETVWNFAHLHQYFDSMAGEQQQQLRKDKNEAAGATSPSAGVMTPYTCVEKSLQVFAKRITKTLINKIGNMVSINDTLLCELKRLKSLIVSFKDDARFISVDFSKVHSRIAHLVASYVTHSQEVSVAMRLQLLQMLRSLRQLLADERGREQHLGCVCASLLLMLEQAPTSAVHLPDTLKTEELCCAAWETEQCCACLWDANLSRKTSRRKRTKSLRAAAVVQSQGQLQDTSGSTGSSALHASLGVGSTSLGASRVVASASKDAWRRQQSDDEDYDSDEQVIFFDCTNVTLPYGSSSEDEENFRTPPQSLSPGISMDLEPRYELFIFGNEPTKRDLDVLNALSNVDIDKETLPHVYAWKTAMESYSCAEMNLFPSPRNVKVQKPEPWYSGTSSSHNSQPLLHPKRLLATPKLNAVVSGRRGSGPLTAPVTPRLARTPSAASIQVASETNGESVGTAVTPASPILSFAALTAATQSFQTPLNKVRGLFSQYRDQRSYNEGDTPLGNRN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :.. :: * : *: *. *. . . . . : . ..:: : : .: : * *: .:. : : * . : . ..: :. .* :*. *. . . .: .. : : ..: .:. .* .:* *.. .: : *. . . * : : : * * :. :. . : : :: .* * .. : : : *: . : * * . : : * . : * :.: . ::* . : * * :. . : . .. . :: ::: * *. *.:*. : . *. **: *: : : : : : . *.. : : *.* : :* * *** :.: :. :..::* :: . *. * . . **.. * :** .:* ::. * : ** .* .:. *. . ..:: . . . * .:: * . **: *:* : * : .*. . :: ::::* *:*:* ***:**:: * ***:**..*:*:.: *** *** *: :: : : * .: :*: *: . :: : :: : :.:. *: . . . . : :. .: :.. .. : .. :. : .*.* . : . :.*: :.: :* : * *. . . ... *. . . . **. *. . . :. .**: *:**:* * *** **. . :* * :: **::: ** :: : :*** ..: . * . . :.* * ..* :. :: * . * : . ", "identical_positions": 130, "similar_positions": 308, "identity": "11.02%" }, { "cls_id": "homologset.agr.MGI:1261864", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R3E3-1", "uniprot_id": "WIPI1_MOUSE", "id": "Q8R3E3-1", "name": "WD repeat domain phosphoinositide-interacting protein 1", "aln": "-----MEAEAADAPPGRVEAALSCFSFNQDCTSLAIGTKAGYKLFSLSSVE-QLDQVHGSNE-------------------------------IPDVYIVERLFSSSLVVVVSHT-----KPRQMNVYHFKKGTEICNYSYSSNILSIRLNRQRLLVCLEES-IYIHNIKDMKLLKTVLDIPSNPTGLCALSINHSNSYLAYPGS--------------------------------------------------------------------QSTGEIVLYDGNSLKTVCTIAAHEGTLAAITFNSSGSK--LASASEKGTVIRVFSVPEGQKLYEFRRGMKRYVTISSLVFSMDSQFLCASSNTETVHIFKMEH-------------------------LTDSRP-----EEPSTWSGYMGKMFMAATN--YLPAQVSDMMNQDRAFATGRLNFSGQKNICTLSTIQKLPRLLVASSDGHLYIYNLDPQDGGECVLIKTHSL----LSSGTTEENKENDLRPSLPPSYAATVARPSTSAASTVPG-----YSE--------------DGGALRGEVIPEHEFATG------------------PVCLDDE--NEFPPIILCRGSQKGKTKQS---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5MNZ9-1", "uniprot_id": "WIPI1_HUMAN", "id": "Q5MNZ9-1", "name": "WD repeat domain phosphoinositide-interacting protein 1", "aln": "-----MEAEAADAPPGGVESALSCFSFNQDCTSLATGTKAGYKLFSLSSVE-QLDQVHGSNE-------------------------------IPDVYIVERLFSSSLVVVVSHT-----KPRQMNVYHFKKGTEICNYSYSSNILSIRLNRQRLLVCLEES-IYIHNIKDMKLLKTLLDIPANPTGLCALSINHSNSYLAYPGS--------------------------------------------------------------------LTSGEIVLYDGNSLKTVCTIAAHEGTLAAITFNASGSK--LASASEKGTVIRVFSVPDGQKLYEFRRGMKRYVTISSLVFSMDSQFLCASSNTETVHIFKLEQ-------------------------VTNSRP-----EEPSTWSGYMGKMFMAATN--YLPTQVSDMMHQDRAFATARLNFSGQRNICTLSTIQKLPRLLVASSSGHLYMYNLDPQDGGECVLIKTHSL----LGSGTTEENKENDLRPSLPQSYAATVARPSASSASTVPG-----YSE--------------DGGALRGEVIPEHEFATG------------------PVCLDDE--NEFPPIILCRGNQKGKTKQS---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8L2Q1U4-1", "uniprot_id": "A0A8L2Q1U4_RAT", "id": "A0A8L2Q1U4-1", "name": "WD repeat domain phosphoinositide-interacting protein 1", "aln": "-----MEAEAADAPPGRVEAALSCFSFNQDCTSLAIGTKTGYKLFSLSSVE-QLDQVHGSNE-------------------------------IPDVYIVERLFSSSLVVVVSHT-----KPRQMNVYHFKKGTEICNYCYSSNILSIRLNRQRLLVCLEES-IYIHNIKDMKLLKTLLDIPSNPTGLCALSINHSNSYLAYPGS--------------------------------------------------------------------QSTGEIVLYDGNSLKMVCTIAAHEGTLAAITFNSSGSK--LASASEKGTVIRVFSVPEGQKLYEFRRGMKRYVTISSLVFSMDSQFLCASSNTETVHIFKLEQ-------------------------LTDSRP-----EEPSTWSGYMGKMLTAATN--YLPAQVSDMMNQDRAFATGRLNFSGQKNICTLSTIQKLPRLLVASSDGHLYIYNLDPQDGGECVLIKTHSL----LSSGTAEENKENDLRPSLPPSYAATVARPSASTASTVPDNLVPWKSEGQNEAVLTRSLPQKSGQPLSGGFGKNKESGRNGMQSMLWAERGGRQEAWAPHCLSHRPWSAPLPKPLSLGCQWARRMLESHNAIQATV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VIE1-1", "uniprot_id": "Q9VIE1_DROME", "id": "Q9VIE1-1", "name": "", "aln": "-------------------MTTYQMNFNQDFTSLSVLSPTGLRLFSISSQD-KVEEIFAKDN-------------------------------TEQIRIVERLFNSSLVVLVTAQ-----KPNCLKMLHFKKKQDICNCFYPSEILCVRMNRQRLIVCLAES-IHIHDIRDMKILHSIENIAPNEQGLCALSLN---SHLAFPVC--------------------------------------------------------------------QTSGELRIFNASKLRTGMTIRAHDTSLSALAFSPSGAL--LATASERGTVIRVFCVKNGQRVQEFRRGVS-CVRIASLVFSASGDFLCASSNTETVHVFKIDTRAVETVELKAIADVAAKSENSAKEAVASTAA-----EESCRPVASWGGMFSKAVSSLLLPTQVSEVLAQDRSFATVQLAQGGLKHICALTRVQKEPRLLIACEDGFLYVHEFPAERGGPCKLMSVHDLRGA-LEDVIELELSESVQRSQTKPSNPSTVTQPSLTMLKSCAASVLIENPD------------PMQDNSYASILKGDQADAMS-----------------DSAKFRKLCDAIDTPTKLYDERQFPPVAITAKD------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "M9PER1-1", "uniprot_id": "M9PER1_DROME", "id": "M9PER1-1", "name": "", "aln": "--------MMSLLGRTDVDAGEVFVNFNQNITSLAVATSGGYSLYSLGSVDSTLDKIYHTK--------------------------------SDELFLIERLFESSLVAIVSQR-----APRKLKVCHFKKQSEICNYSYANTILAVKLNRERLIVCLEES-LYIHNIQDMKVVHTIRDTPCNPQGLCALSSSSEHCYLAYPGS--------------------------------------------------------------------VTAGEVQIFDAINLHAKTMIPAHDTPLAALAFSPSGTE--IATASERGTVIRVFSSQDGSRLFELRRGLKRCVSIVSLSFSTCAEYLVSSSNTETVHIFRLDR------------------------SATETAEGHGSKQSSDDWMGYSFFRFLSKTVTSYLPTQVTDVFSQGRAFASVTLPEAGVRRMCAIATIQKQLRLLIASQDGYLYVYSIPTVEGAECQLIKRHDLR---LEDHYAMDIKVDSPQ-TLGLNSGVSIGGAAGVPPSSASA-----------------------AGAGTGGSGGDGKSAVS-----------------VTGGVDKP--SSSYASAVKGDDPVGPSSA----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P43601-1", "uniprot_id": "ATG18_YEAST", "id": "P43601-1", "name": "Autophagy-related protein 18", "aln": "--------------MSDSSPTINFINFNQTGTCISLGTSKGFKIFNCEPFG-----KFYSED-------------------------------SGGYAIVEMLFSTSLLALVGIGDQPALSPRRLRIINTKKHSIICEVTFPTSILSVKMNKSRLVVLLQEQ-IYIYDINTMRLLHTIETNP-NPRGLMAMSPSVANSYLVYPSPPKVINSEIKAHATTNNITLSVGGNTETSFKRDQQDAGHSDISDLDQYSSFTKRDDADPTSSNGGNSSIIKNGDVIVFNLETLQPTMVIEAHKGEIAAMAISFDGTL--MATASDKGTIIRVFDIETGDKIYQFRRGTY-ATRIYSISFSEDSQYLAVTGSSKTVHIFKLGHS-----------------------------------MSNNKLDSDDSNMEEAAADDSSLDTTSIDALSDEENPTRLAREPYVDASRKTMGRMIRYSSQKLSRRAARTLGQIFPIKVTSLLESSRHFAS----LKLPVETNSHVMTISSIGSPIDIDTSEYPELFETGNSAS----------------------TESYHEPVMKMVPIRVVS-----------------SDGYLYNFVMDPERGGDCLILSQYSILMD----------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q02887-1", "uniprot_id": "ATG21_YEAST", "id": "Q02887-1", "name": "Autophagy-related protein 21", "aln": "MKVLQFNQDATCCVVAASSHQISIFNCDPFGKCFEIDTKNSKKKTSNNNGSASNSESRNNEESILITNGSRDRTDAEEEEDNEDNALVTGNILKEGEFVIEMLFSTSLIAIADRG-QGLNKGKKLKIVNTKRKCTICEIVFPHEIVDVVMNRKRMCVLLESDQIFIYDISCMKPLETIDLWEDHYKRSQANSFSNASNTGTLEGD--------------------------------------------------------------------SANLNRVATNLLANATQKSVNGSNPSVRTRRNSLRSKIRPRMVLSNDDRSILCFTAYSSPKKNKPNSEALYDVVIYDTLNVTPVNYLNSVHKGNVACLAVSHDG---------------------------------KLLATASDKGTIIRVFHTGVDSDYMSSRSLFKEFRRGTRLCNLYQLAFDKSMTMIGCVGDTDTIHLFKLDDASNSLPGDNSSNGHWNEEEYILASNSNPSMGTPKEIPLSKPRIANYFSKKIKSSIPNQNLSRNFAYITVNESNR---------------SCLGFPDEFPNQVYIAS------------------DDGTFSIYSIPSKPGECVLTKNNKFT------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. : ..: : . . .. ::* **.:**:.:. . :.: : *: **: :. *: : :*:.*: * * .. :.*::* *: :.:: : * * . . : : : . . : : . . *: . * * . : : . . * . ::* . :.. : . . : : : : : . : . . . . . ", "identical_positions": 23, "similar_positions": 86, "identity": "3.58%" }, { "cls_id": "homologset.agr.MGI:1261872", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4AEJ5-1", "uniprot_id": "D4AEJ5_RAT", "id": "D4AEJ5-1", "name": "", "aln": "--------------------------------------------MPRRAGSGQLPLPRGWEEARDYDGKVFYIDHNTRRTSWIDPRDRLTKPLSFADCVGDELPWGWEAGFDPQIGAYYIDHINKTTQIEDPRKQWRGEQEKMLKDYLSVAQDALRTQKELYHVKEQRLALALDEYVRLNDAYKEKSSSHTSLFSGSSSSTKYDPDILKAEISTTRLRVKKLKRELSQMKQELLYKQQGFETLQQIDEKMSGGQSG-YELSEAKAILTELKSIRKAISSGEKEKQDLMQSLAKLQERFHLDQNMGSSEPDLRCSPVNSHLSLSRQTLDAGSQTSISGDIG--VRSRSNLAEKVRLSLQYEEAKRSMANLKIELSKLDGEAWPGALDVEKEKLMLINEKEELLKELQFITPQKRTQDELERLEAERQRLEEELVAARGLPSRALAERLKLEEKRKELLQKLEETTKLTTYLYSQLKSLSS-STLSMSSGSSLGSLASSRGSLNTSSRGSLNSLSSSDLYYSSQGDQMDTDYQYKLDFLLQEKGGYIPSGPITTIHENEVVKSPSQPGQSGLCGLGVAATSHTPPLTEASKSVTSLSSRSSLSSLSPPGSPLVLDSTFPGSS-HDTSPHQFTADLEDCELSRHFADIGLGENQVLLDSDSGGPSQSLLEDKDLDECTGGLLYEGSADVEKSLPKRRGLHLRGDKTARVSAAASDESVAGDSGVYEASVKQPGEIEDIPYREEDVTIVETAQVQIGLRYDTKSSSFMVIIAQLRNLHAFSIP--HSSKVYFRVAVLPSSADVSCLFRTKVHPPTESVLYNDVFRVAISQVVLQQKTLRVDLCSVSKRRREECLAGTQISLADLPFSNEIFMLWYNLLPSKQIPCKKKEEGGGQPGAQSPQPALDSADLDAVSALLARTSAELLAVEQELAQEEEEEEEEELRPEHRGPGEDCLTMLREASAETVAAKESGVHLAEGGHCPEDPSPCTRGPGTSRDQCRKEKGRTEDPG-QPATAVPTLVDKETNTDEAVDSNIAVRPKDRSSLSSQHHPFVRSSVIVRSQTFSPGE---RSQYICRLNRSDSDSSTLAKKS--LFVRNSTERRSLRVKRAVCQPTLRRTAQECPVRTSLDLELDLQASLTRQSRLNDELQALRGLQQKLEELKAQGETDLPPGMLGDERFQKLLKQAEKQAEQTKEEQKQDLNAERLMRQVSKDVCRLREQSQ-KEPRQVQSFREKIAYFTRAKISIPSLPADDV----------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6NXJ0-1", "uniprot_id": "WWC2_MOUSE", "id": "Q6NXJ0-1", "name": "Protein WWC2", "aln": "--------------------------------------------MPRRAGSGQLPLPRGWEEARDYDGKVFYIDHNTRRTSWIDPRDRLTKPLSFADCVGDELPWGWEAGFDPQIGAYYIDHINKTTQIEDPRKQWRGEQEKMLKDYLSVAQDALRTQKELYHVKEQRLALALDEYVRLNDAYKEKSSSHTSLFSGSSSSTKYDPDILKAEISTTQLRVKKLKRELSHMKQELLYKQQGFETLQQIDEKMSGGQSG-YELNEAKAILTELKSIRKAISSGEKEKQDLMQSLAKLQERFHLDQNMGSSEPDLRSSPVNSHLSLSRQTLDAGSQTSISGDIG--VRSRSNLAEKVRLSLQYEEAKRSMANLKIELSKLDGEAWPGALDIEKEKLMLINEKEELLKELQFITPQKRSQEELERLEAERQHLEEELMAARGSPSRALTERLKLEEKRKELLQKLEETTKLTTSLYSQLQSLSS-STLSMSSGSSLGSLASSRGSLNTSSRGSLNSLSSSELYYSSQGDQMDTDYQYKLDFLLQEKGGYIPSGPITTIHENEVVKSPSQPGQSGLCGVGVTASSHTTPLTEASKSVASLSSRSSLSSLSPPGSPLVLDSVFPGSS-HDTSPHQFPTDFEDCELSRRFADVGLGENQALLDSDSGGASQPLLEDKGLSDCPGELLCEGATDVEKSLPKRRGLHLRGDKTTRVSAAASDESVAGDSGVYEASMKQPGEMEDVPYSEEDVTIVETAQVQIGLRYDTKSSSFMVIIAQLRNLHAFSIP--HSSKVYFRVALLPSSADVSCLFRTKVHPPTESVLYNDVFRVAVSQAALQQKTLRVDLCSASKHRREECLAGTQISLADLPFSNEIFMLWYNLLPSKQMPCKKNEDGNEEPGARSQQPMLDPIDLDAVSALLARTSAELLAVEQELAQEEEEEE---LRPERRGPGRDCLTMLREASDEPAALRESGVPLAEGSRCTEDPKPCPRGPETS--QCRKEP--AEDPG-QLPSGLPTLVDKETNTDEVVDSNMAVRPKDRSSLSSRQHPFVRNSVIVRSQTFSPGE---RSQYICRLNRSDSDSSTLAKKS--LFVRNSTERRSLRVKRAVCQPTLRRTAQECPVRTSLDLELDLQASLTRQSRLNDELQALRGLRQKLEELKAQGETDLPPGVLEDERFQKLLKQAEKQAEQTKEEQKQDLNAERLMRQVSKDVCRLREQSQ-KEPRQVQSFREKIAYFTRAKISIPSLPADDV----------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6AWC2-1", "uniprot_id": "WWC2_HUMAN", "id": "Q6AWC2-1", "name": "Protein WWC2", "aln": "--------------------------------------------MPRRAGSGQLPLPRGWEEARDYDGKVFYIDHNTRRTSWIDPRDRLTKPLSFADCVGDELPWGWEAGFDPQIGVYYIDHINKTTQIEDPRKQWRGEQEKMLKDYLSVAQDALRTQKELYHVKEQRLALALDEYVRLNDAYKEKSSSHTSLFSGSSSSTKYDPDILKAEISTTRLRVKKLKRELSQMKQELLYKEQGFETLQQIDKKMSGGQSG-YELSEAKAILTELKSIRKAISSGEKEKQDLMQSLAKLQERFHLDQNIGRSEPDLRCSPVNSHLCLSRQTLDAGSQTSISGDIG--VRSRSNLAEKVRLSLQYEEAKRSMANLKIELSKLDSEAWPGALDIEKEKLMLINEKEELLKELQFVTPQKRTQDELERLEAERQRLEEELLSVRGTPSRALAERLRLEERRKELLQKLEETTKLTTYLHSQLKSLSA-STLSMSSGSSLGSLASSRGSLNTSSRGSLNSLSSTELYYSSQSDQIDVDYQYKLDFLLQEKSGYIPSGPITTIHENEVVKSPSQPGQSGLCGVAAAATGHTPPLAEAPKSVASLSSRSSLSSLSPPGSPLVLEGTFPMSSSHDASLHQFTADFEDCELSSHFADISLIENQILLDSDSGGASQSLSEDKDLNECAREPLYEGTADVEKSLPKRRVIHLLGEKTTCVSAAVSDESVAGDSGVYEAFVKQPSEMEDVTYSEEDVAIVETAQVQIGLRYNAKSSSFMVIIAQLRNLHAFLIP--HTSKVYFRVAVLPSSTDVSCLFRTKVHPPTESILFNDVFRVAISQTALQQKTLRVDLCSVSKHRREECLAGTQISLADLPFSSEVFTLWYNLLPSKQMPCKKNEE-NEDSVFQPNQPLVDSIDLDAVSALLARTSAELLAVEQELAQEEEEES---GQEEPRGPDGDWLTMLREASDEIVAEKEAEVKLPEDSSCTEDLSSCTSVPEMNEDGNRKESNCAKDLRSQPPTRIPTLVDKETNTDEAANDNMAVRPKERSSLSSRQHPFVRSSVIVRSQTFSPGE---RNQYICRLNRSDSDSSTLAKKS--LFVRNSTERRSLRVKRTVCQSVLRRTTQECPVRTSLDLELDLQASLTRQSRLNDELQALRDLRQKLEELKAQGETDLPPGVLEDERFQRLLKQAEKQAEQSKEEQKQGLNAEKLMRQVSKDVCRLREQSQ-KVPRQVQSFREKIAYFTRAKISIPSLPADDV----------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VFG8-1", "uniprot_id": "KIBRA_DROME", "id": "Q9VFG8-1", "name": "Protein kibra", "aln": "MPNLQQTASQSQHHLHPHHLRPQQQQQQHHHHHQQQQQQQHTHHQQQQQHHSDFPLPDGWDIAKDFDGKTYYIDHINKKTTWLDPRDCYTKPQTFEDCVGDELPMGWEESYDPNIGPYYINHLAQSTQLEDPRQEWKTVQEQMLSDYLSAAQDQLENKREMFDVKQQRLLWAQEEYN-----HLKLAASRSSLCSSSSSMSRHDPELLRADLMLARERVHQLKQELTHITNDISYTERGMNTLYSVGEKINARENGCYDIAEVHAIREEMLKVHKSLVSGEKVREELMRSLVQIKNELGRQQ----------ISEENSDLASPFDRVCVASQTDLCGSSGENLNGGARFAEMAKTKWQYAEWRKHIKKLQQQLADHVERIEPGQLESDKDRILLIQEKEKLLNDLNSISLKSRSEEEKRVIHQTRHKLEEDLKEAYEANNTCVANRLRFHEEKQLLLDKLQEALKSTKLLEERLKSFSSESTFSISSGSSLGSLSTAS----SKSALSFTDIYIDPFAVDSPIDVVDLRRRSQRLFQQHQQQRLHPVHPVLQQQQSAEVTLSPRSSLS----METPPASPMKYNAGADQTPQALKEEPTYANALPAPPAYTAPPPVPISGVRARPYDLDSTVLDCMMLEAKLQKLNMGTPLNLAVAP----LSPISEKPSLLDLPQEMLSRSSSTSN---------------TRSVSAAVSNESVAGDSGVFEASR-------------AHLPRKELAQVQIGLKYLKQEGVLVVSLERANNLLALWTASADNSQVYLRAALLPNSLTS---IRTKALGDFQKPVFNDTFAVPITLDKLLTKSLQVTVVTMTGQK-EEIIGTVQISMAEFNPE-DSTLKWYNVLSSKFIPS------------------FESLDIPSTSAAAAAAAVAASNAPNPGNNREESSD------ESTITSSQTSTLTRNQAPCMELQEQMAAELLGLGPLNE--PECSDDDDDDEEEELDDKQLVSDVG-LMNSSSMLHAYLQNMKQEFADKETNTDRAYLPEKSRGQSQLMDDRPVKRSQTFTPSEAFSKNRYNCRLNRSDSDSAMHCGVAPHTFQRGAAERRSLRFHSKAPKSVTKLHHTHIPR-TSLDLELDLQAQHSKLYFLNDQIAKLQNLKEVLQKACENKDPLVAAWAIENEEFQRLVARADPAKCPEERQ------LQKLLMKTAKEIHKLRKTKVPKGCPDLVSFKEKITFFTRKGLSVPELPSEFTLPEANPIEEEEEEEDENEFYNSAETAIAINTALVASSNRNKNLSEHPHRATSGAVPKIPAPVVTPAATPAATPAATPAATSAATPAATPVVSPAAQPDAKPADAPIPVASNDAEQQRFDYVVDRNYGVEV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: .::*** **: *:*:***.:**** .::*:*:**** *** :* ******** *** .:**:** ***:*: ::**:****::*: **:**.****.*** *..::*::.**:*** * :** : : ::*::** *.*** :::**::*:*:: :: **::**:**:::.::: *.::*::** .:.:*:.. :.* *:: *.:** *: .::*:: **** :::**:**.::::.: :* * **.*. . : : ..***.:.*. * :.. :.:** .: . ** * :: : :*: :*:. . ** *: :*::::**:***:**::*: :: :.*:::* . :. *::***:* . . .:::**::.*.:: **:**:*: * *. * .:*:*:*: **:*:*********::: :.* *:..: : .* * :* : : * ::: * *: ::. *. ..:.. * : ...:. : * :: :*....: :. *. .. . .* *. : . . .: :: *. :: .:.: * : ..: *. .* : . * ..:: : * ****.*:*********:** .:. * *******:* :.. ::* : : .** *: . ..*:**:*.*:**.* :***. :. ::**.* *.:: * *:*:* : : : :: ** :. .***:*:: . : ***:*.** :*. .:. *: :.** * ::. . : :.**... * .. : *: *: : .: . * . * *. . .: ..* : . :. .:* .:.: . .. * : :: . : *****:*.* :.:* **********: . : * *.::******.: . :.. : . * ***********. :: ***:: *:.*:: *:: : :. :.. : :*.**:*: :*: :.: ::*: :.:*:: :**: . * :: **:***::*** :*:*.**:: . ", "identical_positions": 333, "similar_positions": 426, "identity": "24.1%" }, { "cls_id": "homologset.agr.MGI:1261890", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B2RZ28-1", "uniprot_id": "B2RZ28_RAT", "id": "B2RZ28-1", "name": "", "aln": "MAAASEERMAEEGGGGHGDGGSCSAASSAQRQPPTPPSQALQPGSQAPAAPALAPDHLPQNNTLVALPIVAIENILSFMSYDEISQLRLVCKRMDLVCQRMLNQGFLKVERYHNLCQKQVKAQLPRRESERRNHSLARHADILAAVETRLSLLNMTFMKYVDSNLCCFIPGKVIDEIYRVLRYVNSTRAPQRAHEVLQELRDISSMAMEYFDEKIVPILKRKLPGSDVSGRLMGSPPVPGPSAALTTMQLFSKQNPSRQEVTKLQQQVKTNGAGVTVLRREISELRTKVQEQQKQLQDQDQKLLEQTQIIGEQNARLAE--LERKLREVMESAVGTSSGSGQSE----ESPRKRRKATEAIDSLRKSKRLRNRK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BIG4-1", "uniprot_id": "FBX28_MOUSE", "id": "Q8BIG4-1", "name": "F-box only protein 28", "aln": "MAAASEERMAEEGGGGHGDGGSCSAAGSAQRQPPAPPSQAPPPGSQAPAAPALAPDHLPQNNTLVALPIVAIENILSFMSYDEISQLRLVCKRMDLVCQRMLNQGFLKVERFHNLCQKQVKAQLPRRESERRNHSLARHADILAAVETRLSLLNMTFMKYVDSNLCCFIPGKVIDEIYRVLRYVNSTRAPQRAHEVLQELRDISSMAMEYFDEKIVPILKRKLPGSDVSGRLMGSPPVPGPSAALTTMQLFSKQNPSRQEVTKLQQQVRTNGAGVTVLRREISELRTKVQEQQKQLQDQDQKLLEQTQIIGEQNARLAE--LERKLREVMESAVGTSSGSGQSE----ESPRKRRKATEAIDSLRKSKRLRNRK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NVF7-1", "uniprot_id": "FBX28_HUMAN", "id": "Q9NVF7-1", "name": "F-box only protein 28", "aln": "MAAAAEERMAEEGGGGQGDGGSSLASGSTQRQPPPPAPQHPQPGSQALPAPALAPDQLPQNNTLVALPIVAIENILSFMSYDEISQLRLVCKRMDLVCQRMLNQGFLKVERYHNLCQKQVKAQLPRRESERRNHSLARHADILAAVETRLSLLNMTFMKYVDSNLCCFIPGKVIDEIYRVLRYVNSTRAPQRAHEVLQELRDISSMAMEYFDEKIVPILKRKLPGSDVSGRLMGSPPVPGPSAALTTMQLFSKQNPSRQEVTKLQQQVKTNGAGVTVLRREISELRTKVQEQQKQLQDQDQKLLEQTQIIGEQNARLAE--LERKLREVMESAVGNSSGSGQNE----ESPRKRKKATEAIDSLRKSKRLRNRK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1P937-1", "uniprot_id": "A0A8M1P937_DANRE", "id": "A0A8M1P937-1", "name": "", "aln": "MAAVV---VSADGGVSPVDSGSVSPR---------------------LPSPSPVPEQQQQNNPLLGLPIVAIDTILNFLTYDEISLLRLVCKRMDMICQRMLNQGFLKVERYHSLCQKQVKAQLPRRESERRNHSLARHADILAAVETRLSLLNMTFMKYVDSNLCCFIPGKVIDEIYRVLRYVNSTRAPQRAHEVLQELRDISSMAMEYFDEKIVPILKKRLPGADLSGRLIGSAPVAGPSTSLTTMSLLAKNTPSRSEMTKLQQQVKVNGASMTALRREMQEVRLKQLEQQKQLQDQEQKLQEQSQVIGEQNARLAE--LEHKLRDLMDRAVGAGDPDAAAA----SSQSLCVKRRSCSELPRHSKRLRSKK-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VT01-1", "uniprot_id": "Q9VT01_DROME", "id": "Q9VT01-1", "name": "", "aln": "-------------------------------------------------------------MNLLDLPQTLIQDILELLPYDEVAKKREVCTLFNYLGQQILNKGFNKIIMAHAKNFKRIKSMLPRRESERRNHILSRHSDILTSIETRISMLTMTYSKFIDLNICCFIPGRVLDEINSILRILSTSTKQLRPHEVLQELRDISSMAIEHFDEKIAVNFKLEHRKQLAESTAAGARLVVCSALGDISFSGVRRTGISRPVDHGLVQQAIVQLAPISASKSHSDSSQKDRMSKQLFKQYQLQRSLSQKIRLLEVSRKVQDRRLQEALSSITELTTQVSELKRQMEDVVANMPSCAVKRQAVASADCLPPALKKPKV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: ** . *: **.::.***:: * **. :: : *::**:** *: * *::*: *********** *:**:***:::***:*:*.**: *::* *:******:*:*** :** :.:: *.**************:*:*****. :* . .. *: * .: . ::. . : ** * **. .: * ::. : . .. : . .:* * * *: .*. : * . :: : *:. * .: : :. .. . . * . . *:. * ", "identical_positions": 101, "similar_positions": 93, "identity": "26.93%" }, { "cls_id": "homologset.agr.MGI:1261910", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZU21-1", "uniprot_id": "D3ZU21_RAT", "id": "D3ZU21-1", "name": "", "aln": "MSRKIAKESKKVNISSSLESEDISLETTIHTDDVSSSEEREGKVKITRQLIERKEILHNIQLLKIELSQKNMMIDNLKMDYLTKVEELEEKLNDALHQKQLLTLRLDNQLTIQQKDAKKYQELMKQEMETILLRQKQLEETNHQLREKAGDVRRNLRDLELTEEQYEKLKSFPEDQLSIPEFVSIRFYELVNPLRKEIHELQVKKNELSEELSTNKGQLKQLTETYEEARRNHSELLTRCQRLALELADTKQLVQQGDYRQENYDKVKSERDALEQEVLEVRRKHEVLETSHIAQAKERNELSKEVSTLQQTVTLLQKDKEYLNRQNMELSVRCAHEEDRLERLQVQLEETKRAREEMYEKYVTSRDHYKTEYENKLHDELEQIKLKTNLEIDQLRSASREMYERENRNLREARDNALAEKNRAVTAEKDALEKHEQLLDRYRELQLSTESKVSEFLHQSKLKSFESERVQLLQEETARNLTQCQLECEKYQKKLEVLTKEFYSLQASSEKRITELEAQNSEHQARLDIYEKLEKELDEIIMQTAEIENEDEAERILYSYGYGANVPTTAKRRLKQSVHLARRVLQLEKQNSSILKDLDHQKEEVRQLSQELDRANSLLNQSQQPYRYLIESVRQRDSKIDSLMKCTAQLEKDVSNLNKEKSALLQTKNQMALDLEQLLNHREEFAAMKQIIINMCSKHSENNLLLTKVESKSVTENQASRPLTMPREHEENVFIPKPTLFTKKEAQEWPKNQKMKA-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q6K3-1", "uniprot_id": "E9Q6K3_MOUSE", "id": "E9Q6K3-1", "name": "", "aln": "MSRKIAKEPKKVNISSSLESEDISLETTIHTDDVSSSEEREGKVKITRQLIERKEILHNIQLLKIELSQKNMMIDNLKMDYLTKIEELEEKLNDALHQKQLLTLRLDNQLTIQQKDAKKYQELMKQEMETILLRQKQLEETNHQLREKAGDVRRNLRDFELTEEQYVKLKSFPEDQLSIPEYVSIRFYELVNPLRKEVCELQVKKSELSEELSTSKGQLKQLTETYEEDRRNNAELLIRCQRLTLELADTKQLVQQGDYRQENYDKVKSERDALEQDVLELRRKHEVLEASHIAQAKERNELSKEVSSLQQTVTLLQKDKDYLNRQNMELSVRCAHEEDRLERLQVQLEDTKKAREEMYEKYVTSRDHYKTEYENKLHDELEQIKLKTNLEIDQLRSASREMYERENRNLREARDNALAEKNRAVAAEKDALGKHEQLLDRYRELQLSTESKVSEFLHQSKLKSFESERVQLLQEETARNLTQCQLECEKYQKKLEVLTKEFYSLQTSSEKRITELEAQNSEHQARLDIYEKLEKELDEIIMQTAEIENEDEAERILYSYGYGANVPTTAKRRLKQSVHLARRVLQLEKQNSLILKDLDHQKNQVRQLSQELDRANSLLNQTQQPYRYLIESVRQRDAKIDSLMKSTAQLEKDVSNLNKEKSALLQTKNQMALDLEQLLSHREEFAAMKQIIINMCSKHSENNLFLTKMESKSVTENQA-KTLNMPREHEENIFIPKPTLFTKKEAQEWPKSQKMKT-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WXW3-1", "uniprot_id": "PIBF1_HUMAN", "id": "Q8WXW3-1", "name": "Progesterone-induced-blocking factor 1", "aln": "MSRKISKESKKVNISSSLESEDISLETTVPTDDISSSEEREGKVRITRQLIERKELLHNIQLLKIELSQKTMMIDNLKVDYLTKIEELEEKLNDALHQKQLLTLRLDNQLAFQQKDASKYQELMKQEMETILLRQKQLEETNLQLREKAGDVRRNLRDFELTEEQYIKLKAFPEDQLSIPEYVSVRFYELVNPLRKEICELQVKKNILAEELSTNKNQLKQLTETYEEDRKNYSEVQIRCQRLALELADTKQLIQQGDYRQENYDKVKSERDALEQEVIELRRKHEILEASHMIQTKERSELSKEVVTLEQTVTLLQKDKEYLNRQNMELSVRCAHEEDRLERLQAQLEESKKAREEMYEKYVASRDHYKTEYENKLHDELEQIRLKTNQEIDQLRNASREMYERENRNLREARDNAVAEKERAVMAEKDALEKHDQLLDRYRELQLSTESKVTEFLHQSKLKSFESERVQLLQEETARNLTQCQLECEKYQKKLEVLTKEFYSLQASSEKRITELQAQNSEHQARLDIYEKLEKELDEIIMQTAEIENEDEAERVLFSYGYGANVPTTAKRRLKQSVHLARRVLQLEKQNSLILKDLEHRKDQVTQLSQELDRANSLLNQTQQPYRYLIESVRQRDSKIDSLTESIAQLEKDVSNLNKEKSALLQTKNQMALDLEQLLNHREELAAMKQILVKMHSKHSENSLLLTKTEPKHVTENQKSKTLNVPKEHEDNIFTPKPTLFTKKEAPEWSKKQKMKT-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B6N2-1", "uniprot_id": "A0ACD6B6N2_DANRE", "id": "A0ACD6B6N2-1", "name": "", "aln": "MPPKKPKD-AKANISSSIESEDISLETTVPTEDISSSDEKDGAGKVTKQLLERKELLHNLQKLKIELSQKNLLIDNLKVDHLTKTEELEERLNDALHQKQVLALRLDSQLKLQQDENRKHQALRKQEMDTIMLRQKQLEEMNHQLCDRAGDLRRSLRDLELSEQKYAELKELPEDKLTIPEFVAIRFYEVVNPLRALATELQMKKTDLIEDLDSHRKQIRSLMESYEEERRARSELEIRCQRLTLELADTKQLIQEGDYKRENYEKIKRERDGYETELRELKKKLEILDLTHTALEKERNDLNKEAVNLQQSVTLLQKDKDFLNRQNMELNVRCAHQEDRLDRLQNQLEDSKKAREEAYEKYVASRDHYKTEYENKLRDELERIRMKTSHEIESLQRTSKEMYERENRSLRETRDNSVIERDRALNAERETQAKYDQLLDQFRQLQLGSDSRVAELLNQVKLKKFELERSQMVQEETARNLSLCQIECEKHQKKLEVLTKEFYGLQTSSEKRITELQAQNSEHQARLETYERLEKELDDVTMQAAEMENEDEAERVLFSYGYGANIPTTAKRRLKQSVHLARRVLQLEKQNTLLRRDLERQTAHSSQISEELNAANQLLQQAQQPHSYLIETVRQRDSQIHTLKDRLTRLEEEMSALRKEKIALLQVKNNMAADLERLLNHREELSVMKQVLISMRGPPSAT---LPELEADGTAVHRP-KTFKSTDEEQYN-YGPKPTVFTKKEVPEWYRKVKRKTK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. * .*: *.*****:**********: *:*:***:*::* ::*:**:****:***:* ********.::*****:*:*** *****:*********:*:****.** :**.: *:* * ****:**:******** * ** ::***:**.***:**:*::* :** :***:*:***:*::****:***** ***:**. * *:*.: : *::.* *:*** *: :*: *****:*********:*:***::***:*:* ***. * :: *:::* *:*: :* ***.:*.**. .*:*:********::********.*****:****:*** ***::*:**** *****:*************:****:*::**. **:.*: :*:********.***:***:: *::**: **::: *::****::*:***.::*:*:*:*:* ***.** ** *::********: **:****:************.**:*********:**********: **:******:: **:**:********:*:*******:*************************: : :**:::. . *:*:**: **.**:*:***: ****:*****::*.:* . ::**:::* *.*** ****.**:** ***:**.****::.***:::.* . * . *.: *.. .: :: :.:. . *.: * : ****:*****. ** :. * *: ", "identical_positions": 461, "similar_positions": 204, "identity": "60.82%" }, { "cls_id": "homologset.agr.MGI:1261912", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6NS60-1", "uniprot_id": "FBX41_MOUSE", "id": "Q6NS60-1", "name": "F-box only protein 41", "aln": "MASLDLPYRCPRCGEHKRFRSLSSLRAHLEYSHTYETLYILSKTNSICDGAAAAAAAAAAASGFPLAPEPAALLAVPGARREVFESTSFQGKEQATGPSPAGPHLLHHHHHHAPLAHFPADLVPASLPCEELAEPGLVP--AARYALREIEIPLGELFARKSVASSACSTPPPGPGPGPCSGPSSASPASPSPADVAYEEGLARLKIRALEKLEVDRRLERLSEEVEQKIAGQVGRLQAELERKAAELETARQESARLGREKEELEERASELSRQVDVSVELLASLKQDLVHKEQELSRKQQEVVQIDQFLKETAAREASAKLRLQQFIEELLERADRAERQLQVISSSCGSTPSASLGRGGGGSASGPGVRGPGRMREHHAGSAVPSTYAVSRHGSSPSTGASSRVPAASQSSGCYDSDSLELPRPEEGPSEDSGPGGLGSRAQATNGGSERSQAPRSSGLRRQAIQNWQRRPRRHSTEGEEGDVSDVGSRTTESEAEGPSDVPRP-GPAVAGPLNSCRLSARPEGGSGRGRRVERGSPSRSNEVISPEILKMRAALFCIFTYLDTRTLLHAAEVCRDWRFVARHPAVWTRVLLENARVCSKFLAMLAQWCTQAHSLTLQNLKPRQRGKKESKEEYARSTRGCLEAGLESLLKAAGGNLLILRISHCPNILTDRSLWLASCYCRALQAVTYRSATDPVGHEVIWALGAGCRDIVSLQVAPLHPCQQPTRFSNRCLQMIGRCWPHLRALGVGGAGCGVQGLASLARNCMRLQVLELDHVSEITQEVAAEVCREGLKGLEMLVLTATPVTPKALLHFNSICRNLKSIVVQIGIADYFKEPSSPEAQKLFEDMVTKLQALRRRPGFSKILHIKVEGGC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0M8C7-1", "uniprot_id": "A0ABK0M8C7_RAT", "id": "A0ABK0M8C7-1", "name": "F-box only protein 41", "aln": "MASLDLPYRCPRCGEHKRFRSLSSLRAHLEYSHTYETLYILSKTNSICDGAAAAAAAAAAASGFPLAPEPAALLAVPGARREVFESTSFQGKEQAAGPAPAGPHLLHHHHHHAPLAHFPGDLVPASLPCEELAEPGLVP--AARYALREIEIPLGELFARKSVASSACSTPPPGPGPGPCSGPTSASPASPSPADVAYEEGLARLKIRALEKLEVDRRLERLSEEVEQKIAGQVGRLQAELERKAAELETARQESARLGREKEELEERASELSRQVDVSVELLASLKQDLVHKEQELSRKQQEVVQIDQFLKETAAREASAKLRLQQFIEELLERADRAERQLQVISSSCGSTPSASLGRGGGGSASGPGLRGPGRMREHHAGPAVPSTYAVSRHGSSPSTGASSRVPAASQSSGCYDSDSLELPRQEEGPSEDSGPGGLGSRAQATNGGSERSQPPRSSGLRRQAIQNWQRRPRRHSTEGEEGDVSDVGSRTTESEAEGPSDVPRP-GPAVAGPLNSCRLSARPEGGSGRGRRMERGSPSRSNEVISPEILKMRAALFCIFTYLDTRTLLHAAEVCRDWRFVARHPAVWTRVLLENARVCSKFLAMLAQWCTQAHSLTLQNLKPRQRGKKESKEEYARSTRGCLEAGLESLLKAAGGNLLILRISHCPNILTDRSLWLASCYCRALQAVTYRSATDPVGHEVIWALGAGCRDIVSLQVAPLHPCQQPTRFSNRCLQMIGRCWPHLRALGVGGAGCGVQGLASLARNCMRLQVLELDHVSEITQEVAAEVCREGLKGLEMLVLTATPVTPKALLHFNSICRNLKSIVVQIGIADYFKEPSSPEAQKLFEDMVTKLQALRRRPGFSKILHIKVEGGC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8TF61-1", "uniprot_id": "FBX41_HUMAN", "id": "Q8TF61-1", "name": "F-box only protein 41", "aln": "MASLDLPYRCPRCGEHKRFRSLSSLRAHLEYSHTYETLYILSKTNSICDGAAAAAAAAAAASGFPLAPEPAALLAVPGARREVFESTSFQGKEQAAGPSPAAPHLLHHHHHHAPLAHFPGDLVPASLPCEELAEPGLVPAAAARYALREIEIPLGELFARKSVASSACSTPPPGPGPGPCPGPASASPASPSPADVAYEEGLARLKIRALEKLEVDRRLERLSEEVEQKIAGQVGRLQAELERKAAELETARQESARLGREKEELEERASELSRQVDVSVELLASLKQDLVHKEQELSRKQQEVVQIDQFLKETAAREASAKLRLQQFIEELLERADRAERQLQVISSSCGSTPSASLGRGGGGGGAGPNARGPGRMREHHVGPAVPNTYAVSRHGSSPSTGASSRVPAASQSSGCYDSDSLELPRPEEGAPEDSGPGGLGTRAQAANGGSERSQPPRSSGLRRQAIQNWQRRPRRHSTEGEEGDVSDVGSRTTESEAEGPLDAPRP-GPAMAGPLSSCRLSARPEGGSGRGRRAERVSPSRSNEVISPEILKMRAALFCIFTYLDTRTLLHAAEVCRDWRFVARHPAVWTRVLLENARVCSKFLAMLAQWCTQAHSLTLQNLKPRQRGKKESKEEYARSTRGCLEAGLESLLKAAGGNLLILRISHCPNILTDRSLWLASCYCRALQAVTYRSATDPVGHEVIWALGAGCREIVSLQVAPLHPCQQPTRFSNRCLQMIGRCWPHLRALGVGGAGCGVQGLASLARNCMRLQVLELDHVSEITQEVAAEVCREGLKGLEMLVLTATPVTPKALLHFNSICRNLKSIVVQIGIADYFKEPSSPEAQKLFEDMVTKLQALRRRPGFSKILHIKVEGGC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F6NUQ2-1", "uniprot_id": "F6NUQ2_DANRE", "id": "F6NUQ2-1", "name": "", "aln": "MASLDLPYRCPRCGEHKRFRSLSSLRAHLEYNHTYETLYVLSKSNSVCDAAALLPLVADG--------------ALTAESRFPYRELPCSGEELGLAPSSTACYLPN------------------------------------------VEFPLGEILVKTAMSSSDALSSAGN------NAVAVAANVAASAVEAAYEEGLARLKARAFERLELDERLEKLSEEVEQKISARVSRLQAELERKSSELEKAKLESERLSQEKQDLEDKATELSRQVDVSVEMLASLKQDLVNKEQELSHKQQEVSQIDQFLQETAAREANAKLRLQQFIEELLDRADRAEKQLQIISN-CGTTPNGSLGHCSLGSKSN------GRQRNSSLSGVSRGMYQVSDRRSSPSTAASVRGKSVSQGSGGYDSDSVDLHALEDCP-DAQYYHVQCRLGEGGGAGYERAAASRSWGLRKQAIQNWQRRPYRNSMEGEEGDVSDVGSRTTESEAEMWEQDRRADSSQHAGHRGGYRLPTGRSEGGYKACRHEK-SPSKGSEVISPEVLKMRAALFCIFTYLDTKTLLRAAEVCRDWRSVARHPAVWTRVLLENARICSKFLCTLSQWCTQTHSLILQNLKPRQRGKKETKEEYLKSTRGCLEEGLEALLKGTGSNLLILKVSHCPNLLTDRSLWLASCYCRALQAVTYRSATDPVGQEVIWALGAGCRDIISLQVAPLHPCQQPARFSNRCLQTIGRCWPHLRALGVGGAGCGIQGLASLARNCMRLQVLELDHVSEINQEVAAEMCREGLKGLEMLVLTSTPVTPKALLHFNSVCRNLKSIVVQIGIEDYFEDPNSPEARKLFDEMVNKLQALKKRPGFSKILHVKADGLC", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*******************************.*******:***:**:**.** . .* . *:.. * :.. . .*:* . .*:.:. :* : :*:****::.:.:::** . :.. . . : *: .:.*..:.********** **:*:**:*.***:*********:.:*.*********::***.*: ** **.:**::**::*:***********:*********:******:***** ******:*******.*************:******:***:**. **:**..***: . *. :. ** *: . . . * ** : *****.** * :.**.** *****::* *: . : . .:. ..* **: ..** ***:********** *:* ******************** : *. .. ** .. **.: . *. :. * *: ***:..******:****************:***:********* *****************:*****. *:*****:*** *************:**** :******* ***:***.:*.*****::*****:*****************************:***********:*:*************:******** *******************:************************.******:**************:*************:************* ***::*.****:***::**.*****::*********:*.:* *", "identical_positions": 553, "similar_positions": 165, "identity": "63.13%" }, { "cls_id": "homologset.agr.MGI:1270126", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O70405-1", "uniprot_id": "ULK1_MOUSE", "id": "O70405-1", "name": "Serine/threonine-protein kinase ULK1", "aln": "MEPGRGGVETVGKFEFSRKDLIGHGAFAVVFKGRHREKHDLEVAVKCINKKNLAKSQTLLGKEIKILKELKHENIVALYDFQEMANSVYLVMEYCNGGDLADYLHTMRTLSEDTVRLFLQQIAGAMRLLHSKGIIHRDLKPQNILLSNPGGRRANPSNIRVKIADFGFARYLQSNMMAATLCGSPMYMAPEVIMSQHYDGKADLWSIGTIVYQCLTGKAPFQASSPQDLRLFYEKNKTLVPAIPRETSAPLRQLLLALLQRNHKDRMDFDEFFHHPFLDASTPIKKSPPVPVPSYPSSGSGSSSSSSSASHLASPP-SLGEMPQL-QKTLTSP-ADAAGFLQGSRDSGG----SSKDSCDTDDFVMVPAQFPGDLVAEAASAKPPPDSLLCSGSSLVASAGLESHGRTPSPSPTCSSSPSPSGRPGPFSSNRYG---ASVPIPVPTQVHNYQRIEQNLQSPTQQQTARSSAIRRSGSTTPLGFGRASPSPPSHTD-GAMLARKLSLGGGRPYTPSPQ------VGTIPERPSWSRVPSPQGADVRVGRSPRPGSSVPEHSPRTTGLGCRLHSAPNLSDFH-VVRPKLPKPPTDPLGATFSPPQTSAPQPCPGLQSCRPLRGSPKLPDFLQRSPLPPILGSPTKAGPSFDFPKTPSSQNLLTLLARQGVVMTPPRNRTLPDLSEASPFHGQQLGSGLRPAEDTRGPFGRSFSTSRITDLLLKAAFGTQASDSGSTDSLQ-EKPMEIAPSAGFGGTLHPGARGGGASSPAPVVFTVGSPPSGATPPQSTRTRMFSVGSSSSLGSTGSSSARHLVPGACGEAP--ELSAPGHCCSLADPLAANLEGAVTFEAPDLPEETLMEQEHTETLHSLRFTLAFAQQVLEIAALKG--SASEAAGGPEYQLQESVVADQISQLSREWGFAEQLVLYLKVAELLSSGLQTAIDQIRAGKLCLSSTVKQVVRRLNELYKASVVSCQGLSLRLQRFFLDKQRLLDGIHGVTAERLILSHAVQMVQSAALDEMFQHREGCVPRYHKALLLLEGLQHTLTDQADIENIAKCKLCIERRLSALLSGVYA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZMG0-1", "uniprot_id": "D3ZMG0_RAT", "id": "D3ZMG0-1", "name": "Serine/threonine-protein kinase", "aln": "MEPGRGGVETVGKFEFSRKDLIGHGAFAVVFKGRHREKHDLEVAVKCINKKNLAKSQTLLGKEIKILKELKHENIVALYDFQEMANSVYLVMEYCNGGDLADYLHTMRTLSEDTVRLFLQQIAGAMQLLHSKGIIHRDLKPQNILLSNPGGRRANPSNIRVKIADFGFARYLQSNMMAATLCGSPMYMAPEVIMSQHYDGKADLWSIGTIVYQCLTGKAPFQASSPQDLRLFYEKNKTLVPAIPRETSAPLRQLLLALLQRNHKDRMDFDEFFHHPFLDASTPIKKSPPVPVPSYPSSGSGSSSSSSSASHLASPP-SLGEMPQL-QKTLTSP-ADAAGFLQGSRDSGG----SSKDSCDTDDFVMVPAQFPGDLVPEAASAKPPPDSLLCSGSSLVASAGLESHGRTPSPSPTCSSSPSPSGRPGPFSSNRYG---ASVPIPVPTQVHNYQRIEQNLQSPTQQQTARSSAIRRSGSTSPLGFGRASPSPPSHTD-GAMLARKLSLGGGRPYTPSPQATLFLPVGTIPERPSWSRVPSPQGADVRAGRSPRPGSSVPEHSPRTTGLGCRLHSAPNLSDFH-VVRPKLPKPPTDPLGATFSPPQTSAPQPCPGLQSCRPLRGSPKLPDFLQRSPLPPILGSPTKAGPSFDFPKAPSSQSLLTLLARQGVVMTPPRNRTLPDLSEAGPFQGQQLGSGLRPAEDTRGPFGRSFSTSRLTDLLLKAAFGTQASDSGSTDSLQ-EKPMEIAPSAGFGGTLHPGARAGGASSPAPVVFTVGSPPSGTTPPQSTRTRMFSVGSSSSLGSTGSSSARHLVPGACAEAP--ELSAPGYCCSLADPLAANLEGAVTFEAPDLPEETLMEQEHTETLHSLRFTLAFAQQVLEIAALKG--SASEAAGGPEYQLQESVVADQISQLSREWGFAEQLVLYLKVAELLSSGLQTAIDQIRAGKLCLSSTVKQVVRRLNELYKASVVSCQGLSLRLQRFFLDKQRLLDGIHGVTAERLILSHAVQMVQSAALDEMFQHRESCVPRYHKALLLLEGLQHTLTDQADIENIAKCKLCIERRLSALLSGVYA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75385-1", "uniprot_id": "ULK1_HUMAN", "id": "O75385-1", "name": "Serine/threonine-protein kinase ULK1", "aln": "MEPGRGGTETVGKFEFSRKDLIGHGAFAVVFKGRHREKHDLEVAVKCINKKNLAKSQTLLGKEIKILKELKHENIVALYDFQEMANSVYLVMEYCNGGDLADYLHAMRTLSEDTIRLFLQQIAGAMRLLHSKGIIHRDLKPQNILLSNPAGRRANPNSIRVKIADFGFARYLQSNMMAATLCGSPMYMAPEVIMSQHYDGKADLWSIGTIVYQCLTGKAPFQASSPQDLRLFYEKNKTLVPTIPRETSAPLRQLLLALLQRNHKDRMDFDEFFHHPFLDASPSVRKSPPVPVPSYPSSGSGSSSSSSSTSHLASPP-SLGEMQQL-QKTLASP-ADTAGFLHSSRDSGG----SKDSSCDTDDFVMVPAQFPGDLVAEAPSAKPPPDSLMCSGSSLVASAGLESHGRTPSPSPPCSSSPSPSGRAGPFSSSRCG---ASVPIPVPTQVQNYQRIERNLQSPTQFQTPRSSAIRRSGSTSPLGFARASPSPPAHAEHGGVLARKMSLGGGRPYTPSPQ------VGTIPERPGWSGTPSPQGAEMRGGRSPRPGSSAPEHSPRTSGLGCRLHSAPNLSDLH-VVRPKLPKPPTDPLGAVFSPPQASPPQPSHGLQSCRNLRGSPKLPDFLQRNPLPPILGSPTKAVPSFDFPKTPSSQNLLALLARQGVVMTPPRNRTLPDLSEVGPFHGQPLGPGLRPGEDPKGPFGRSFSTSRLTDLLLKAAFGTQAPDPGSTESLQ-EKPMEIAPSAGFGGSLHPGARAGGTSSPSPVVFTVGSPPSGSTPPQGPRTRMFSAGPTG----SASSSARHLVPGPCSEAPAPELPAPGHGCSFADPITANLEGAVTFEAPDLPEETLMEQEHTEILRGLRFTLLFVQHVLEIAALKG--SASEAAGGPEYQLQESVVADQISLLSREWGFAEQLVLYLKVAELLSSGLQSAIDQIRAGKLCLSSTVKQVVRRLNELYKASVVSCQGLSLRLQRFFLDKQRLLDRIHSITAERLIFSHAVQMVQSAALDEMFQHREGCVPRYHKALLLLEGLQHMLSDQADIENVTKCKLCIERRLSALLTGICA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B606-1", "uniprot_id": "A0ACD6B606_DANRE", "id": "A0ACD6B606-1", "name": "non-specific serine/threonine protein kinase", "aln": "-------METVGKFEFSRKDLIGHGAFAVVFKGRHREKHEWEVAVKCINKKNLAKSQTLLGKEIKILKELKHENIVALHDFQETASSVYLVMEYCNGGDLADYLHSKGTLSEDTIRVFLQQITGAMRVLQAKGIIHRDLKPQNILLSHPAGRKSHFNNTCIKIADFGFARYLQNNMMAATLCGSPMYMAPEVIMSQNYDAKADLWSIGTIVFQCLTGKAPFQASSPQDLRLFYEKNKTLSPNIPRETSTHLRHLLLGLLQRNHKDRMDFDEFFRHPFLEASSSMKKSTPVTVTCFPNSASASSCSSSSTSHLASPPQSLAEIQQVRAKALASPTQDSPGYLLKDSGGGGGGSSSKNSSCDTDDFVMVPAHFPSELTCDMPTGKVLQDSLMYSGSSLLASGGQCSQGKTPPRSPSFSSSPGPSGRPSEFSGSSYGNYGQSVPIPVPTQIHNYQRMEQNFQFPGQEGSPRSGLAQRCSSGSFLACGRTGPSPPRSGS--AVMSRRLSTGGSKPFQLSPQ------VGTIPELP---GQVCPASAEVG-YRGSRGGE--AKTWPQQQGLGTRLNSAPCLLEAAGGCRQKIRKQHSDPV----VAPQAN-------VMPFRTLHSSPRLSELMQRNPLPTILGSPSRAMPPFEFPKPPSSPNMVTFLTQQGLRTAQ----------------GEPSYSPAYQPEERKG-FGRSQSAGRLSDVLLMAAFGGQRGERGSMENLNTDRAIDITAPPGGGG------IVVGSGSPARVVFTIGSPPSGATPPQNSRSRKLSAGSSSSVSPVGSLTSRYTQAGNYMDCYE-GSSSPRYG--FSDPISA-----VTFEAPELPEETLMEQEHTETLCRLRFMLDFARCMVEVAGARSGEMAQTELSSTSLLQQQSLMADQISSLSREWSYAEQLVLYMKTAELLSSSLQTAMEGIKQGKLYPSSTVKQVVRRLNDLYKSSVMSCRSLSNQLERFFTRKHKLMDHINSITAERLLFGHTVQMVQAAALDEMFHQGEASIQRYHKALLLMEGLSLLLTEQADILSISKCKQCIERRLTALQSGLCV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *******************************: *************************************:**** *.*******************: ******:*:*****:***::*::****************:*.**::: .. :************.**********************:**.***********:*************************** * ******: **:***.****************:****:**..::**.**.*..:*.*.*.**.****:******* **.*: *: *:*:** *:.*:* . ..** *...************:**.:*. : .:.* ***: *****:**.* *:*:**. **. ****.****.. **.. * *********::****:*:*:* * * :.**. :*..* : *. .*:.**** . .:::*::* **.:*: *** ****** * .* .*:: *..* *. .: *: *** **:*** * : * *: * :**: .**:. : . * *:.**:*.:::**.***.*****::* *.*:***.*** .::::*::**: : *: . *: :* **** *:.*::*:** **** * : ** :.*: ::.::*:...* ** *:.**: ****:******:****..*:* :*.*.:. .* ::*: .* :. .:* : ::**::* ******:************* * *** * *.: ::*:*. :. *. .... *:*::***** *****.:*******:*.******.**:*:: *: *** ************:***:**:**:.** :*:*** *::*:* *:.:*****::.*:*****:*******:: *..: ********:***. *::**** .::*** ******:** :*: .", "identical_positions": 595, "similar_positions": 254, "identity": "55.4%" }, { "cls_id": "homologset.agr.MGI:1270128", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D0RB01-1", "uniprot_id": "UBP12_RAT", "id": "D0RB01-1", "name": "Ubiquitin carboxyl-terminal hydrolase 12", "aln": "-----------------------------------------MEILMTVSKFASICTMGANASALEKEIG----------------------------------------------------------PEQFPVNE---HYFGLVNFGNTCYCNSVLQALYFCRPFRDKVLAYKSQPRK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KESLLTCLADLFHSIATQKKKVGVIPPKKFITRLRKENELFDNYMQQDAHEFLNYLLNTIADILQEERKQEKQ-NGRLR-----------------------------NGDVDSEDNNSTP-------------------------------------DPTWVHEIFQGTLTNETRCLTCETISSKDEDFLDLSVDVEQN--TSITHCLRGFSNTETLCSEYKYYCEECRSKQEAHKRMKVKKLPMILALHLKRFKYMDQLHRYTKLSYRVVFPLELRLFNTSGDATNPDRMYDLVAVVVHCGSGPNRGHYIAIVKSHDF-WLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGYILFYQSRD------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6A8N5-1", "uniprot_id": "A0A8I6A8N5_RAT", "id": "A0A8I6A8N5-1", "name": "ubiquitinyl hydrolase 1", "aln": "---------------------------------------------MTVSKFASICTMGANASALEKEIG----------------------------------------------------------PEQFPVNE---HYFGLVNFGNTCYCNSILQALYFCRPFRDKVLAYKSQPRK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KESLLTCLADLFHSIATQKKKVGVIPPKKFITRLRKENELFDNYMQQDAHEFLNYLLNTIADILQEERKQEKQ-NGRLR-----------------------------NGDVDSEDNNSTP-------------------------------------DPTWVHEIFQGTLTNETRCLTCETISSKDEDFLDLSVDVEQN--TSITHCLRGFSNTETLCSEYKYYCEECRSKQEAHKRMK--KLPMILALHLKRFKYMDQLHRYTKLSYRVVFPLELRLFNTSGDATNPDRMYDLVAVVVHCGSGPNRGHYIAIVKSHDF-WLLFDDDIVEKIDAQAIEEFYGLTSDISKNSES---RDFQSRD------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D9M2-1", "uniprot_id": "UBP12_MOUSE", "id": "Q9D9M2-1", "name": "Ubiquitin carboxyl-terminal hydrolase 12", "aln": "-----------------------------------------MEILMTVSKFASICTMGANASALEKEIG----------------------------------------------------------PEQFPVNE---HYFGLVNFGNTCYCNSVLQALYFCRPFREKVLAYKSQPRK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KENLLTCLADLFHSIATQKKKVGVIPPKKFITRLRKENELFDNYMQQDAHEFLNYLLNTIADILQEERKQEKQ-NGRLR-----------------------------NGDVDNEDNNSTP-------------------------------------DPTWVHEIFQGTLTNETRCLTCETISSKDEDFLDLSVDVEQN--TSITHCLRGFSNTETLCSEYKYYCEECRSKQEAHKRMKVKKLPLILALHLKRFKYMDQLHRYTKLSYRVVFPLELRLFNTSGDATNPDRMYDLVAVVVHCGSGPNRGHYIAIVKSHDF-WLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGYILFYQSRD------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75317-1", "uniprot_id": "UBP12_HUMAN", "id": "O75317-1", "name": "Ubiquitin carboxyl-terminal hydrolase 12", "aln": "-----------------------------------------MEILMTVSKFASICTMGANASALEKEIG----------------------------------------------------------PEQFPVNE---HYFGLVNFGNTCYCNSVLQALYFCRPFREKVLAYKSQPRK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KESLLTCLADLFHSIATQKKKVGVIPPKKFITRLRKENELFDNYMQQDAHEFLNYLLNTIADILQEERKQEKQ-NGRLP-----------------------------NGNIDNENNNSTP-------------------------------------DPTWVHEIFQGTLTNETRCLTCETISSKDEDFLDLSVDVEQN--TSITHCLRGFSNTETLCSEYKYYCEECRSKQEAHKRMKVKKLPMILALHLKRFKYMDQLHRYTKLSYRVVFPLELRLFNTSGDATNPDRMYDLVAVVVHCGSGPNRGHYIAIVKSHDF-WLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGYILFYQSRD------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A4FUN7-1", "uniprot_id": "UBP12_DANRE", "id": "A4FUN7-1", "name": "Ubiquitin carboxyl-terminal hydrolase 12A", "aln": "-----------------------------------------MEILMTVSKFASFCTMGANASALEKEIG----------------------------------------------------------SEQFPVNE---HYFGLVNFGNTCYCNSVLQALYFCRPFREKILAYRSQPRR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KENLLTCLADLFHSIANQKRKVGVIPPKKFITRLRKENELFDNYMQQDAHEFLNYLLNTIADLLQEERKQDKQ-NGKLA-----------------------------NGTLDSQNNNSTPP------------------------------------STTWVHEIFQGTLTNETRCLTCETISSKDEDFLDLSVDVEQN--TSITHCLRGFSNTETLCSEYKYYCEECRSKQEAHKRMRVKKLPMILALHLKRFKYMEQLQRYTKLSYRVVFPLELRLFNTSGDATNPERLYDLVAVVVHCGSGPNRGHYIAIVKSHDF-WLLFDDDIVEKIDAQAIEEFYGLTSEISKNSESGYILFYQSRD------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E7F4N9-1", "uniprot_id": "E7F4N9_DANRE", "id": "E7F4N9-1", "name": "Ubiquitin carboxyl-terminal hydrolase", "aln": "-----------------------------------------MEILMTVRKIASICTMGANASALEKEIG----------------------------------------------------------PEQFPVNE---HYFGLVNFGNTCYCNSVLQALYFCRPFREKVLAYKIQPRR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KESLLTCLADLFNSIATQKKKVGVIPPKKFISRLRKENELFDNYMQQDAHEFLNYLLNTIADLLQEEKSQERQQNGKVVQNGGSG------------------SGGGGSGSSTGEGETEEKT------------------------------------QQTWVHEIFQGTLTNETRCLNCEAVSSKDEDFLDLSVDVEQN--TSITHCLRGFSNTETLCSEYKYYCEQCRSKQEAQKRMRVKKLPMILALHLKRFKYMDQLHRYTKLSYRVVFPLELRLFNTSGDATNPDRLYDLVAVVVHCGSGPNRGHYITIVKSHGF-WLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGYILFYQSRD------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VCT9-1", "uniprot_id": "UBP12_DROME", "id": "Q9VCT9-1", "name": "Ubiquitin carboxyl-terminal hydrolase 12/46 homolog", "aln": "--------------------------------------------------------MGANVSQLEREIG----------------------------------------------------------SDLFPPNE---HYFGLVNFGNTCYSNSVLQALYFCKPFREKVLEYKAKNKRP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KETLLSCLADLFYSIATQKKKVGSIAPKKFITRLRKEKEEFDNYMQQDAHEFLNFLINHINEIILAERNAGPS-NGNPKATNQGGSTSAMASSIASKSSSTSNSNSNSNSTTNSNGNSSNSTGSLNANTSVLDASGSLTATTTPIISGNGTGTNGANSEPTWVHEIFQGILTSETRCLNCETVSSKDENFFDLQVDVDQN--TSITHCLRCFSNTETLCSDNKFKCDNCCSYQEAQKRMRVKKLPMILALHLKRFKYMEQFNRHIKVSHRVVFPLELRLFNTSDDAVNPDRLYDLTAVVIHCGSGPNRGHYISIVKSHGL-WLLFDDDMVDKIEASTIEDFYGLTSDIHKSSETGYILFYQSRDCA----------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38187-1", "uniprot_id": "UBP13_YEAST", "id": "P38187-1", "name": "Ubiquitin carboxyl-terminal hydrolase 13", "aln": "MIRRWLTISKSGKKKKAVNDTITEEVEKVDFKPVNHDINDELCYSES-SDNPSSSLFVSNLDTKETFLNEDNNLQISSGLDYSSETCNQGSNYSQDGIFYISNAKAINAYGGIITQGPEAPILAMKVSDSMPYGDGSNKVFGYENFGNTCYCNSVLQCLYNLSSLRENILQFPKKSRESDQPRKKEMRGKKPRIFTEASFEKSIAGTN---GHLPNPKPQSVDDGKPTPVNSVNSNTAGPSEKKSKFFKSFSAKHVQDNNKKEGSPAILTTGKPSSRPQDAPPLIVETPNEPGAPSRLSFENVTDRPPDVPR-KIIVGRVLNYENPSRGSSNSNNLDLKGESNSSLSTPLDKKDTRRSSSSSQ----ISPEHRKKSALIRGPVLNIDHSLNGSDKATLYSSLRDIFECITENTYLTGVVSPSSFVDVLKRENVLFNTTMHQDAHEFFNFLLNELSEYIERENKKIAA------------------------------------SDINSDSEPSK--------------------------------------SKNFISDLFQGTLTNQIKCLTCDNITSRDEPFLDFPIEVQGDEETDIQEILKSYHQREMLNGSNKFYCDECCGLQEAERLVGLKQLPDTLTLHLKRFKYSEKQNCNIKLFNNIHYPLTLNVCSSINSKVCQK--YELAGIVVHMGGGPQHGHYVSLCKHEKFGWLLFDDETVEAVKEETVLEFTGESPNMATAYVLFYKAMYSNAVEKNDRENMAK------EQDDNIDNLIKYDDWLR----TCNSGQKKKEELPIADDLDTAIDDSFVSNTPIKSSKKKSRMFSFRKS", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P39967-1", "uniprot_id": "UBP9_YEAST", "id": "P39967-1", "name": "Ubiquitin carboxyl-terminal hydrolase 9", "aln": "MIKRWLSVNRK-KSHPEKNTQGNDEINRKATSLKKTKGSGDPSIAKSPSAKSSTSSIPSNLASHERRSKFSSQTDNLAGNKHYHEHYHNMASTSDEREYDSSTTYEDRAFD------TESSILFTTITDLMPYGDGSNKVFGYENFGNTCYCNSVLQCLYNIPEFRCNVLRYPERVAAVNRIRKSDLKGSKIRVFTNESFETSTNSGNSNTGYQSNDNEDAHNHHHLQQSDQDNSSSSTQEKQNNFERKRNSFMGFGKDKSNYKDSAKKDDNNEMERPQPVHTVVMASDTLTEKLHEGCKKIIVGRPLLKQSDSLSKASTTDCQANSHCQCDSQGSRITSVDDDVLVNPESCNDAVNNSNNNKENTFPTSEQRKKAALIRGPVLNVDHLLYPTEEATLYNGLKDIFESITENLSLTGIVSPTEFVKILKKENVLFNTMMQQDAHEFLNFLLNDFSEYIQRNNPRMRF------------------------------------GPQKTDNS-----------------------------------------NDNFITDLFKGTLTNRIKCLTCDNITSRDEPFLDFPIEVQGDEETDIQKMLKSYHQREMLNGVNKFYCNKCYGLQEAERMVGLKQLPHILSLHLKRFKYSEEQKSNIKLFNKILYPLTLDVSSTFNTSVYKK--YELSGVVIHMGSGPQHGHYVCICRNEKFGWLLYDDETVESIKEETVLQFTGHPGDQTTAYVLFYKETQADKTE-NQNENIDTSSQDQMQTDNNIEQLIKCDDWLRDRKLRAAANIERKKTLGNIPEVKTAETKTPLNDKKRNKQKRKSRILSFIK-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :* * .: :* .: : ** *******.**:**.** :* ::* : : : .* . * *:* .*: : .* :.*..*: *::*: *:. *:******:*:*:* : : : :. . :.. . .:: ::*:* **.. :**.*: ::*:** *:*: ::*: : *.* . *: : : * * . *: *::* . ***.: : :** *:******** :: : *: .: :** * : .: . . . *:* .:*:* *.**::***: : : . : ***:**: *: :. .:: :* * . : . . ", "identical_positions": 98, "similar_positions": 121, "identity": "11.64%" }, { "cls_id": "homologset.agr.MGI:1270129", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P63036-1", "uniprot_id": "DNJA1_RAT", "id": "P63036-1", "name": "DnaJ homolog subfamily A member 1", "aln": "MVKETTYYDVLGVKPNATQEELKKAYRKLALKYHPDKN-PNE--GEKFKQISQAYEVLADSKKRELYDKGG---------EQAIK----EGGAGGG-----------FGSPMDIFDMFFGG--------------------------------------------GGRMQR-ERRGKNVVHQLSVTLEDLYNGATRKLALQKNVICDKCEGRGGKKGAVECCPNCRGTGMQIRIHQIGPGMVQQIQSVCMECQGHGERISPKDRCKSCNGRKIVREKKILEVHIDKGMKDGQKITFHGEGD--------QEPGLEPGDIIIVLDQKDHAVFTRRGED--LFMCMDIQLVEALCGFQKPIS-TLDNRTIVITSHPGQIVKHGDIKCVLNEGMPIYRRPYE--KGRLIIEFKVNFPENGFLSPDKLSLLEKLLPE--RKEVEET-----------------DEMDQVELVDFDPNQE---------------RRRHYNGEAYEDDEHHPRGG---VQCQTS--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P63037-1", "uniprot_id": "DNJA1_MOUSE", "id": "P63037-1", "name": "DnaJ homolog subfamily A member 1", "aln": "MVKETTYYDVLGVKPNATQEELKKAYRKLALKYHPDKN-PNE--GEKFKQISQAYEVLADSKKRELYDKGG---------EQAIK----EGGAGGG-----------FGSPMDIFDMFFGG--------------------------------------------GGRMQR-ERRGKNVVHQLSVTLEDLYNGATRKLALQKNVICDKCEGRGGKKGAVECCPNCRGTGMQIRIHQIGPGMVQQIQSVCMECQGHGERISPKDRCKSCNGRKIVREKKILEVHIDKGMKDGQKITFHGEGD--------QEPGLEPGDIIIVLDQKDHAVFTRRGED--LFMCMDIQLVEALCGFQKPIS-TLDNRTIVITSHPGQIVKHGDIKCVLNEGMPIYRRPYE--KGRLIIEFKVNFPENGFLSPDKLSLLEKLLPE--RKEVEET-----------------DEMDQVELVDFDPNQE---------------RRRHYNGEAYEDDEHHPRGG---VQCQTS--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P31689-1", "uniprot_id": "DNJA1_HUMAN", "id": "P31689-1", "name": "DnaJ homolog subfamily A member 1", "aln": "MVKETTYYDVLGVKPNATQEELKKAYRKLALKYHPDKN-PNE--GEKFKQISQAYEVLSDAKKRELYDKGG---------EQAIK----EGGAGGG-----------FGSPMDIFDMFFGG--------------------------------------------GGRMQR-ERRGKNVVHQLSVTLEDLYNGATRKLALQKNVICDKCEGRGGKKGAVECCPNCRGTGMQIRIHQIGPGMVQQIQSVCMECQGHGERISPKDRCKSCNGRKIVREKKILEVHIDKGMKDGQKITFHGEGD--------QEPGLEPGDIIIVLDQKDHAVFTRRGED--LFMCMDIQLVEALCGFQKPIS-TLDNRTIVITSHPGQIVKHGDIKCVLNEGMPIYRRPYE--KGRLIIEFKVNFPENGFLSPDKLSLLEKLLPE--RKEVEET-----------------DEMDQVELVDFDPNQE---------------RRRHYNGEAYEDDEHHPRGG---VQCQTS--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VFV9-1", "uniprot_id": "Q9VFV9_DROME", "id": "Q9VFV9-1", "name": "", "aln": "MVKETGYYDILGVKPNATPDELKKAYRKLALKYHPDKN-PNE--GEKFKAISQAYEVLSDADKRQVYDEGG---------EAAIK----KGGADSGD----------FRNPMDFFEKFFGAGFGGS---------------------------------------GGGRRR-ERRGKDVVHQMSVQLEELYNGATRKLQLQKNVICDKCEGRGGKKGSIEKCLQCRGNGVETRVQQIAPGIMQHIEQVCRKCSGTGETIQEKDRCKNCSGRKTVRERKVLEVHIEKGMRDGQKIVFTGEGD--------HEPESQPGDIIILLDEKEHSTFAHAGQD--LMMKMPLQLVEALCGFQRIVK-TLDDRDLIVSTQPGEVIRHEMTKCIAEEGMPIFKNPME--KGTLIIQFEVIFPE--VINPSVVPTLKQCLPP--APEVDIP-----------------IDAEQTVLEDFDPKQ----------------RRQQHQRMAYDEDDGGYQDGPRVQQCTSS--------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P25491-1", "uniprot_id": "MAS5_YEAST", "id": "P25491-1", "name": "Mitochondrial protein import protein MAS5", "aln": "MVKETKFYDILGVPVTATDVEIKKAYRKCALKYHPDKN-PSEEAAEKFKEASAAYEILSDPEKRDIYDQFG---------EDGLSGAGGAGGFPGGG----------FGFGDDIFSQFFGAG-------------------------------------------GAQRPRGPQRGKDIKHEISASLEELYKGRTAKLALNKQILCKECEGRGGKKGAVKKCTSCNGQGIKFVTRQMGP-MIQRFQTECDVCHGTGDIIDPKDRCKSCNGKKVENERKILEVHVEPGMKDGQRIVFKGEAD--------QAPDVIPGDVVFIVSERPHKSFKRDGDD--LVYEAEIDLLTAIAGGEFALE-HVSGDWLKVGIVPGEVIAPGMRKVIEGKGMPIPKYGG---YGNLIIKFTIKFPENHFTSEENLKKLEEILPPRIVPAIPKK-----------------ATVDECVLADFDPAKY---------------NRTRASRGGANYDSDEEEQGGEGVQCASQ--------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P53940-1", "uniprot_id": "APJ1_YEAST", "id": "P53940-1", "name": "J domain-containing protein APJ1", "aln": "MQQNTSLYDSLNVTAAASTSEIKKAYRNAALKYHPDKNNHTEESKRKFQEICQAYEILKDNRLRALYDQYGTTDEVLIQEQQAQAQRQQAGPFSSSSNFDTEAMSFPDLSPGDLFAQFFNSSATPSSNGSKSSFNFSFNNSSTPSFSFVNGSGVNNLYSSSAKYNSNDEDHHLDRGPDIKHNLKCTLKELYMGKTAKLGLNRTRICSVCDGHGGLKK--CTCKTCKGQGIQTQTRRMGP-LVQSWSQTCADCGGAGVFVKNKDICQQCQGLGFIKERKILQVTVQPGSCHNQLIVLTGEGDEVISTKGGGHEKVIPGDVVITILRLKDPNFQVINYSNLICKKCKIDFMTSLCGGVVYIEGHPSGKLIKLDIIPGEILKPGCFKTVEDMGMPKFINGVRSGFGHLYVKFDVTYPER--LEPENAKKIQNILANDKYIKAERSTMETADSDCYCDLEKSYDSVEEHVLSSFEAPNLNNEVIEDDDLGDLINERDSRKRNNRRFDESNINNNNETKRNKYSSPVSGFYDHDINGY", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* ::* ** *.* *: *:*****: ********* .* .**: . ***:* * * :**: * : . * .. *:* **.. . : ** :: *::. *::** * * ** *:: :*. *:*:** * * *.* *:: :::.* ::* . * * * * :. ** *:.*.* .*:*:*:* :: * ..* *.: **.* ***::: : . . * . . : :::: ::.* :. .. : : **::: * : *** * * ::* : :** . . ::: *. :: * .*:. : .* . *. . . : . ", "identical_positions": 102, "similar_positions": 110, "identity": "19.14%" }, { "cls_id": "homologset.agr.MGI:1270148", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P51589-1", "uniprot_id": "CP2J2_HUMAN", "id": "P51589-1", "name": "Cytochrome P450 2J2", "aln": "MLAAMGSLAAALWAVVHPRT-----------LLLGTVAFLLAADFLKRRRPKNYPPGPWRLPFLGNFFLVDFEQSHL-----EVQLFVKKYGN---LFSLELGDISAVLITGLPLIKEALIHMDQNFGNRPVTPMREHIFKKNGLIMSSGQAWKEQRRFTLTALRNFGL-----GKKSLEERIQEEAQHLTEAIKEENGQP------FDPHFKINNAVSNIICSITFGERFEYQDSWFQQLLKLLDEVTYLEASKTCQLYNVFPWIMKFLP--GPHQTLFSNWKKLKLFVSHMIDKHR---KDWNPAETRDFIDAYLKEMSKHTGNPTSS------FHEENLICSTLDLFFAGTETTSTTLRWALLYMALYPEIQEKVQAEIDRVIGQGQQPSTAAR---ESMPYTNAVIHEVQRMGNIIPLNVPREVTVDTTLAGYHLPKGTMILTNLTALHRDPTEWATPDTFNPDHFLE-NGQFKKREAFMPFSIGKRACLGEQLARTELFIFFTSLMQKFTFRPPNNE-KLSLKFRMGITISPVSHRLCAVPQV-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O54750-1", "uniprot_id": "CP2J6_MOUSE", "id": "O54750-1", "name": "Cytochrome P450 2J6", "aln": "MLAATGSLLATIWAALHPRT-----------LLVAAVTFLLLADYFKNRRPKNYPPGPWGLPFVGNIFQLDFGQPHL-----SIQPLVKKYGN---IFSLNLGDITSVVITGLPLIKEALTQMEQNIMNRPLSVMQERISNKNGLIFSSGQIWKEQRRFALMTLRNFGL-----GKKSLEERMQEEASHLVEAIREEEGKP------FNPHFSINNAVSNIICSVTFGERFDYHDSRFQEMLRLLDEVMYLETTMISQLYNIFPWIMKYIP--GSHQKVFRNWEKLKLFVSCMIDDHR---KDWNPDEPRDFIDAFLKEMTKYP-EKTTS------FNEENLICSTLDLFFAGTETTSTTLRWALLYMALYPEVQEKVQAEIDRVIGQKRAARLADR---ESMPYTNAVIHEVQRMGNIIPLNVPREVAMDTNLNGFHLPKGTMVLTNLTALHRDPKEWATPDVFNPEHFLE-NGQFKKRESFLPFSMGKRACLGEQLARSELFIFFTSLMQKFTFNPPINE-KLSPKFRNGLTLSPVSHRICAVPRQ-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M1PZ56-1", "uniprot_id": "A0A8M1PZ56_DANRE", "id": "A0A8M1PZ56-1", "name": "", "aln": "------MDMLHFYEWIDIKS-----------ILIFVCVFLLLSDFIKNKTPKNFPPGPWSLPIIGDIHHIDPSKLHL-----QLSEFAEKYGK---IFSLRLFGPRIVVLNGYNLVKEVYTQEGDNLADRAILPLFHDIIGDKGLVASSGYKWKQQRRFALSTLRNFGL-----GKKNLEPSINLESGFLNEAISNEQGQP------FDPRLLLNNAVSNVICALVFGNRFDYSDHKFQTLLKNINETVHLEGGICAQLYNMLPWLMRLLP--GPHKRIIALWGKLIEFVGEKVNEHK---VDHDPLNPRDYIDCFLDEMEKHKDDTAAG------FDVENLCICTLDLFVAGTETTSTTLYWGLLYMMKYPEIQAKVQQEIDVIVGGSRQPSVSDR---DNMPYTNAVIHEIQRMGNIIPINLARTTSEDTQIEKYSIPKGTMVTSNLTSVLFDESEWETPHSFNPGHFLDAEGKFRRRDAFLPFSLGKRVCLGEQLARMELFLFFSSLLQRFTFSPPAGV-EPSLDYNLGATHCPQPYKLCAVPH------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32TES7-1", "uniprot_id": "A0AB32TES7_DANRE", "id": "A0AB32TES7-1", "name": "", "aln": "---MSSVFSQLIGQWLDVQG-----------FLIFLCVLLLVKHFR-DVYSKNMPPGPFPLPFVGNLTNIGFSDPLG-----SFQRIAEKYGD---VCTLYLGTKPCILMTGYETLKEAFVEQADIFTDRPYFPIVDKLGNGKGLIMSSGHMWRQQRRFALATLKYFGV-----GKKTLENAILQECRFLCDSLQAERGLP------FDPQHLVTNAVSNIICGLVFGHRFEYDDHQFHLMQTYINNILQLPISNWGRLYNEFPTLMSLLP--GKHQTAFASMSKLQPFLKEEIIKHQ---QDREPSSPRDYIDCYLEEIEKCK-DSDAE------FTEENLMFCVVDLFGAGTETTSNTLRWALAFMVKYPDVQEKVQSEIDQVIGQTRQPLMDDR---TNLPYTYAVIHEIQRFANIVTFTPPRVANKDTTVGGQLIPKGVIVLPMLKPILLDKKEYSTPYDFNPAHFLDQNGKFLKKENFIPFSIGKRMCPGEQLARMELFLFFISLMQHFTFLPVEGQ-KLSLKGTTSVSSAPQPFQIRAVPR------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q95078-1", "uniprot_id": "CP18A_DROME", "id": "Q95078-1", "name": "Cytochrome P450 18a1", "aln": "-MLADSYLIKFVLRQLQVQQDGDAQHLLMVFLGLLALVTLLQWLVRNYRELRKLPPGPWGLPVIGYLLFMG-SEKHT-----RFMELAKQYGS---LFSTRLGSQLTVVMSDYKMIRECFRREE--FTGRPDTPFMQTLNG-YGIINSTGKLWKDQRRFLHDKLRQFGMTYMGNGKQQMQKRIMTEVHEFIGHLHASDGQP------VDMSPVISVAVSNVICSLMMSTRFSIDDPKFRRFNFLIEEGMRLFGEIHTVDYIPTMQCFPSIS--TAKNKIAQNRAEMQRFYQDVIDDHK---RSFDPNNIRDLVDFYLCEIEKAKAEGTDAELFDGKNHEEQLVQVIIDLFSAGMETIKTTLLWINVFMLRNPKEMRRVQDELDQVVGRHRLPTIEDL---QYLPITESTILESMRRSSIVPLATTHSPTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTEGKVRKPEYFIPFGVGRRMCLGDVLARMELFLFFASFMHCFDIALPEGQPLPSLKGNVGATITPESFKVCLKRRPLGPTAADPHHMRNVGAN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V399-1", "uniprot_id": "CP303_DROME", "id": "Q9V399-1", "name": "Probable cytochrome P450 303a1", "aln": "----------------MFYT-----------VIWIFCATLLAILFGGVRKPKRFPPGPAWYPIVGSALQVSQLRCRLGMFCKVIDVFARQYVNPYGFYGLKIGKDKVVIAYTNDAISEMMTNEDIDGRPDGIFYRLRTFNSRLGVLLTDGEMWVEQRRFILRHLKNFGF-----ARSGMMDIVHNEATCLLQDLKDKVLKSGGKQTRIEMHDLTSVYVLNTLWCMLSGRRYE-PGSPEITQLLETFFELFKNIDMVGALFSHFPLLRFIAPNFSGYNGFVESHRSLYTFMSKEIELHR--LTYKNYDEPRDLMDSYLRAQDE--GNDEKG-----MFSDQSLLAICLDMFLAGSETTNKSLGFCFMHLVLQPEIQERAFQEIKEVVGLERIPEWSRD--RTKLPYCEAITLEAVRMFMLHTFGIPHRAVCDTRLSGYEIPKDTMVIACFRGMLINPVDFPDPESFNPDRYLFDG-HLKLPEAFNPFGFGRHRCMGDLLGRQNLFMFTTTVLQNFKMVAIPGQ-VPEEVPLEGATAAVKPYDIMLVAREQ----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VW43-1", "uniprot_id": "CP305_DROME", "id": "Q9VW43-1", "name": "Probable cytochrome P450 305a1", "aln": "--------------MSALIF-----------LCAILIGFVIYSLISSARRPKNFPPGPRFVPWLGNTLQFRKEASAVGGQHILFERWAKDFRS--DLVGLKLGREYVVVALGHEMVKEVQLQEVFEGRPDNFFLRLRTMGTRKGITCTDGQLWYEHRHFAMKQMRNVGY-----GRSQMEHHIELEAEELLGQLERTEEQP------IEPVTWLAQSVLNVLWCLIAGKRIARQEDGTLRRLLDLMNRRSKLFDICGGLLAQFPWLRHVAPDRTGYNLIQQLNTELYGFFMDTIEEHRRQLAKDPSPAESDLIYAYLQEMKDRSAGGESS-----TFNETQLVMTILDFFIAGSQTTSNTINLALMVLAMRPDVQEKLFSQVTASVAAASTDAFPHLSRREAFDYMDAFIMEVQRFFHITPITGPRRALWATKLGGYDIPKNATILISLRSVHLDKEHWKDPLEFRPERFIDSAGKCFKDEYFMPFGMGRRRCLGDALARACIFSFLVRIVQHFSVVLPAGE-SPSMVLLPGITLTPKPYKVQFVKRT-----------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :: :. **** * :* . . ...: . . : :: : * . : *: : * * ::*:* :: .* .:. : : * : : . .: * * : : . * . : .: * : *: * : :* . .* :*:* ** :* ..:: : *. : :: :. : : * * : .: .: . : :* . : : : : : * *.* ::: : : * **..*:: * *: *.* :* * .:: * . . . . : .. : : ", "identical_positions": 45, "similar_positions": 106, "identity": "7.96%" }, { "cls_id": "homologset.agr.MGI:1270149", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P51589-1", "uniprot_id": "CP2J2_HUMAN", "id": "P51589-1", "name": "Cytochrome P450 2J2", "aln": "--------MLAAMGSLAAALWAVVHPRTLLLGTVAFLLAADFLKRRRPKN--YPPGPWRLPFLGNFFLVDFEQSHL-----EVQLFVKKYGN---LFSLELGDISAVLITGLPLIKEALIHMDQNFGNRPVTPMREHIFKKNGLIMSSGQAWKEQRRFTLTALRNFGL-----GKKSLEERIQEEAQHLTEAIKEENGQP------FDPHFKINNAVSNIICSITFGERFEYQDSWFQQLLKLLDEVTYLEASKTCQLYNVFPWIMKFLP--GPHQTLFSNWKKLKLFVSHMIDKHR---KDWNPAETRDFIDAYLKEMSKHTGNPTSS------FHEENLICSTLDLFFAGTETTSTTLRWALLYMALYPEIQEKVQAEIDRVIGQGQQPSTAAR---ESMPYTNAVIHEVQRMGNIIPLNVPREVTVDTTLAGYHLPKGTMILTNLTALHRDPTEWATPDTFNPDHFLE-NGQFKKREAFMPFSIGKRACLGEQLARTELFIFFTSLMQKFTFRPPNNE-KLSLKFRMGITISPVSHRLCAVPQV-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O54749-1", "uniprot_id": "CP2J5_MOUSE", "id": "O54749-1", "name": "Cytochrome P450 2J5", "aln": "--------MIMFLSSLVTTFWEALHLKTLVLAVVTFLFLINILRSRHPKN--YPPGPWRLPFVGNFFQIDTKQTHL-----VLQQFVKKYGN---VFSLELGQSPVVVVSGLPLIKEMFTHLDQNFVNRFMTPVRERITGKNGLVVSNGQTWKEQRRLALMALRNFGL-----GKKSLEERIQEETHHLVEAIREEGGQP------FNPHLKLINAVSNIICSVTFGERFDYEDCQFQELLQLLDETMHLMGSSAGQLYNGFPCIMKYLP--GPHQKIFRNWGKLKLFVSHIVKKHE---KDWNPDEPRDFIDAFLIEMQKDP-DRTTS------FNEENLISTTLDLFLGGTETTSSTLRWALLYMSSYPEIQENVQAEIDRVIGHKRQVSLSDR---ESMPYTNAVIHEVQRMGNIVPLNSSREVTVDTKFNGFHLPKGTMILTNLTALHRDPKEWATPEVFNPEHFLE-NGQFKKRESFLPFSMGKRACLGEQLAKSELFIFFSALMQKFTFKPPINE-KLSLKFRMGLILSPASYRICAIPRV-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M1PZ56-1", "uniprot_id": "A0A8M1PZ56_DANRE", "id": "A0A8M1PZ56-1", "name": "", "aln": "--------------MDMLHFYEWIDIKSILIFVCVFLLLSDFIKNKTPKN--FPPGPWSLPIIGDIHHIDPSKLHL-----QLSEFAEKYGK---IFSLRLFGPRIVVLNGYNLVKEVYTQEGDNLADRAILPLFHDIIGDKGLVASSGYKWKQQRRFALSTLRNFGL-----GKKNLEPSINLESGFLNEAISNEQGQP------FDPRLLLNNAVSNVICALVFGNRFDYSDHKFQTLLKNINETVHLEGGICAQLYNMLPWLMRLLP--GPHKRIIALWGKLIEFVGEKVNEHK---VDHDPLNPRDYIDCFLDEMEKHKDDTAAG------FDVENLCICTLDLFVAGTETTSTTLYWGLLYMMKYPEIQAKVQQEIDVIVGGSRQPSVSDR---DNMPYTNAVIHEIQRMGNIIPINLARTTSEDTQIEKYSIPKGTMVTSNLTSVLFDESEWETPHSFNPGHFLDAEGKFRRRDAFLPFSLGKRVCLGEQLARMELFLFFSSLLQRFTFSPPAGV-EPSLDYNLGATHCPQPYKLCAVPH------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32TES7-1", "uniprot_id": "A0AB32TES7_DANRE", "id": "A0AB32TES7-1", "name": "", "aln": "-----------MSSVFSQLIGQWLDVQGFLIFLCVLLLVKHFR-DVYSKN--MPPGPFPLPFVGNLTNIGFSDPLG-----SFQRIAEKYGD---VCTLYLGTKPCILMTGYETLKEAFVEQADIFTDRPYFPIVDKLGNGKGLIMSSGHMWRQQRRFALATLKYFGV-----GKKTLENAILQECRFLCDSLQAERGLP------FDPQHLVTNAVSNIICGLVFGHRFEYDDHQFHLMQTYINNILQLPISNWGRLYNEFPTLMSLLP--GKHQTAFASMSKLQPFLKEEIIKHQ---QDREPSSPRDYIDCYLEEIEKCK-DSDAE------FTEENLMFCVVDLFGAGTETTSNTLRWALAFMVKYPDVQEKVQSEIDQVIGQTRQPLMDDR---TNLPYTYAVIHEIQRFANIVTFTPPRVANKDTTVGGQLIPKGVIVLPMLKPILLDKKEYSTPYDFNPAHFLDQNGKFLKKENFIPFSIGKRMCPGEQLARMELFLFFISLMQHFTFLPVEGQ-KLSLKGTTSVSSAPQPFQIRAVPR------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q95078-1", "uniprot_id": "CP18A_DROME", "id": "Q95078-1", "name": "Cytochrome P450 18a1", "aln": "MLADSYLIKFVLRQLQVQQDGDAQHLLMVFLGLLALVTLLQWLVRNYRELRKLPPGPWGLPVIGYLLFMG-SEKHT-----RFMELAKQYGS---LFSTRLGSQLTVVMSDYKMIRECFRR--EEFTGRPDTPFMQTLNG-YGIINSTGKLWKDQRRFLHDKLRQFGMTYMGNGKQQMQKRIMTEVHEFIGHLHASDGQP------VDMSPVISVAVSNVICSLMMSTRFSIDDPKFRRFNFLIEEGMRLFGEIHTVDYIPTMQCFPSIS--TAKNKIAQNRAEMQRFYQDVIDDHK---RSFDPNNIRDLVDFYLCEIEKAKAEGTDAELFDGKNHEEQLVQVIIDLFSAGMETIKTTLLWINVFMLRNPKEMRRVQDELDQVVGRHRLPTIEDL---QYLPITESTILESMRRSSIVPLATTHSPTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTEGKVRKPEYFIPFGVGRRMCLGDVLARMELFLFFASFMHCFDIALPEGQPLPSLKGNVGATITPESFKVCLKRRPLGPTAADPHHMRNVGAN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V399-1", "uniprot_id": "CP303_DROME", "id": "Q9V399-1", "name": "Probable cytochrome P450 303a1", "aln": "------------------------MFYTVIWIFCATLLAILFGGVRKPKR--FPPGPAWYPIVGSALQVSQLRCRLGMFCKVIDVFARQYVNPYGFYGLKIGKDKVVIAYTNDAISEMMTNEDIDGRPDGIFYRLRTFNSRLGVLLTDGEMWVEQRRFILRHLKNFGF-----ARSGMMDIVHNEATCLLQDLKDKVLKSGGKQTRIEMHDLTSVYVLNTLWCMLSGRRYE-PGSPEITQLLETFFELFKNIDMVGALFSHFPLLRFIAPNFSGYNGFVESHRSLYTFMSKEIELHR--LTYKNYDEPRDLMDSYLRAQDE--GNDEKG-----MFSDQSLLAICLDMFLAGSETTNKSLGFCFMHLVLQPEIQERAFQEIKEVVGLERIPEWSRD--RTKLPYCEAITLEAVRMFMLHTFGIPHRAVCDTRLSGYEIPKDTMVIACFRGMLINPVDFPDPESFNPDRYLFDG-HLKLPEAFNPFGFGRHRCMGDLLGRQNLFMFTTTVLQNFKMVAIPGQ-VPEEVPLEGATAAVKPYDIMLVAREQ----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VW43-1", "uniprot_id": "CP305_DROME", "id": "Q9VW43-1", "name": "Probable cytochrome P450 305a1", "aln": "----------------------MSALIFLCAILIGFVIYSLISSARRPKN--FPPGPRFVPWLGNTLQFRKEASAVGGQHILFERWAKDFRS--DLVGLKLGREYVVVALGHEMVKEVQLQEVFEGRPDNFFLRLRTMGTRKGITCTDGQLWYEHRHFAMKQMRNVGY-----GRSQMEHHIELEAEELLGQLERTEEQP------IEPVTWLAQSVLNVLWCLIAGKRIARQEDGTLRRLLDLMNRRSKLFDICGGLLAQFPWLRHVAPDRTGYNLIQQLNTELYGFFMDTIEEHRRQLAKDPSPAESDLIYAYLQEMKDRSAGGESS-----TFNETQLVMTILDFFIAGSQTTSNTINLALMVLAMRPDVQEKLFSQVTASVAAASTDAFPHLSRREAFDYMDAFIMEVQRFFHITPITGPRRALWATKLGGYDIPKNATILISLRSVHLDKEHWKDPLEFRPERFIDSAGKCFKDEYFMPFGMGRRRCLGDALARACIFSFLVRIVQHFSVVLPAGE-SPSMVLLPGITLTPKPYKVQFVKRT-----------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : **** * :* . . ...: . . : :: : * . : *: : * * ::*:: :: .* .:. : : * : : . .: * * : : . * . : .: * . : *. * : :* .. .* :*:* .* :* ..:: : *. . :: :. : : * * : .: .: . . :* . : : : : : * *.* ::: : : * **..*:: * *: *.: :* * .:: * . . . . .. : : ", "identical_positions": 42, "similar_positions": 108, "identity": "7.45%" }, { "cls_id": "homologset.agr.MGI:1270150", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D309-1", "uniprot_id": "FAM3B_MOUSE", "id": "Q9D309-1", "name": "Protein FAM3B", "aln": "MRPVATGIFKALVFIFSSLCAWYSGYLLAELIPDVPLSSTLYNIRSIGERPVLKAPAPKRQKCDHWSPCPPDTYAYRLLSGGGRDKYAKICFEDEVLIGEKTGNVARGINIAVVNYETGKVIATKYFDMYEGDNSGPMAKFIQSTPSKSLLFMVTHDDGSSKLKAQAKDAIEALGSKEIKNMKFRSSWVFVAAKGFELPSEIEREKINHSDQSRNRYAGWPAEIQIEGCIPKGLR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2KAG4-1", "uniprot_id": "A0A0G2KAG4_RAT", "id": "A0A0G2KAG4-1", "name": "", "aln": "------------------------------------------------MRPVTAAPVPKRQKCDHWSPCPPDTYAYRLLSGGGLDKYAKICFEDEMLLGEKTGNVARGINIAVVDYETGKVISTKYFDMYEGDNSEPMTKFIQSIPSKSLLFMVTHDDGSHKLQAQAKDAIEALGSKEIKNIKFRSSWVFVAAKGFELPSEMEREKINHSDQSRNRYSGWPAEIQIEGCIPKGLR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P58499-1", "uniprot_id": "FAM3B_HUMAN", "id": "P58499-1", "name": "Protein FAM3B", "aln": "MRPLAGGLLKVVFVVFASLCAWYSGYLLAELIPDAPLSSAAYSIRSIGERPVLKAPVPKRQKCDHWTPCPSDTYAYRLLSGGGRSKYAKICFEDNLLMGEQLGNVARGINIAIVNYVTGNVTATRCFDMYEGDNSGPMTKFIQSAAPKSLLFMVTYDDGSTRLNNDAKNAIEALGSKEIRNMKFRSSWVFIAAKGLELPSEIQREKINHSDAKNNRYSGWPAEIQIEGCIPKERS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *** **.*********:***.************ .*********::*:**: **********:*:* **:* :*: ********* **:***** ..********:**** :*: :**:**********:*:********:****:*****::******** ..***:************** ", "identical_positions": 141, "similar_positions": 30, "identity": "60.0%" }, { "cls_id": "homologset.agr.MGI:1270152", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q60870-1", "uniprot_id": "REEP5_MOUSE", "id": "Q60870-1", "name": "Receptor expression-enhancing protein 5", "aln": "--------------MRERFDRFLHEKN-CMTDLLAKLEAKTGVNRSFIALGV--IGLVALYLVFGYGASLLCNLIGFGYPAYISMKAIESPNKDDDTQWLTYWVVYGVFSIAEFFSDLFLSWLPFYYMLKCGFLLWCMAPSPANGAEMLYRRIIRPIFLRHESQVDSVVKDVKDKAKETADAISKEVKKATVNLLGDVKKST", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B2RZ37-1", "uniprot_id": "REEP5_RAT", "id": "B2RZ37-1", "name": "Receptor expression-enhancing protein 5", "aln": "----------MSAAMRERFDRFLHEKN-CMTDLLAKLEAKTGVNRSFIALGV--IGLVALYLVFGYGASLLCNLIGFGYPAYISMKAIESPNKDDDTQWLTYWVVYGVFSIAEFFSDLFLSWFPFYYMLKCGFLLWCMAPSPSNGAELLYRRVIRPIFLKHESQVDSVVKDVKDKAKETADAISKEVKKATVNLLGDEKKST", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q00765-1", "uniprot_id": "REEP5_HUMAN", "id": "Q00765-1", "name": "Receptor expression-enhancing protein 5", "aln": "----------MSAAMRERFDRFLHEKN-CMTDLLAKLEAKTGVNRSFIALGV--IGLVALYLVFGYGASLLCNLIGFGYPAYISIKAIESPNKEDDTQWLTYWVVYGVFSIAEFFSDIFLSWFPFYYMLKCGFLLWCMAPSPSNGAELLYKRIIRPFFLKHESQMDSVVKDLKDKAKETADAITKEAKKATVNLLGEEKKST", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PBX9-1", "uniprot_id": "REEP5_DANRE", "id": "Q6PBX9-1", "name": "Receptor expression-enhancing protein 5", "aln": "----------MAAALKQRFDNALHEKN-MVTDLLAKIEAKTGVNRSYIAYAV--IAFIAIYLVIGYGASLLCNLIGFVYPAYISIKAIESPAKDDDTKWLTYWVVYGVFSVVEFFADIFLSWFPFYFLAKCAFLVWCMAPTPSNGSIMLYTRIIRPFFLKNEAKIDNVMKDLTDKAAGAADKIKDEAKKATANIMFEEKKHY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z9M2-1", "uniprot_id": "A1Z9M2_DROME", "id": "A1Z9M2-1", "name": "Receptor expression-enhancing protein", "aln": "---MATQVKQFLNGYKDDVSKSLRDASKPWTKVFDTVEEKTGVDRVNIFVGA--VGLCAIYLIFGWGAQLLCNIIGVLYPAYISIHAIESSTKQDDTKWLIYWVTFGIFTVIEFFSSLLTSVIPFYWLLKCAFLIWCMLPTEQNGSTIIYNKLVRPYFLKHHESVDRIID---DGMKKAAGVLKHD----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VBM3-1", "uniprot_id": "Q9VBM3_DROME", "id": "Q9VBM3-1", "name": "Receptor expression-enhancing protein", "aln": "MAAQVSQVQRFFNGYKQDINRSLRDASKPWTKAFDSLEEKTGVERVNIFVGS--ILFCAFYLVFGWCAQLLCNIIGVLYPAYISIHGIESSTKQDDIRWLIYWVTFGIFTVIEFYPSLLTSMIPFYWLLKCTFLIWCMLPTERNGSTLIYHKLVRPYFLKLHDPVD----------MMSAGVPKDD----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12402-1", "uniprot_id": "YOP1_YEAST", "id": "Q12402-1", "name": "Protein YOP1", "aln": "-------MSEYASSIHSQMKQFDTKYS--GNRILQQLENKTNLPKSYLVAGLGFAYLLLIFINVGGVGEILSNFAGFVLPAYLSLVALKTPTSTDDTQLLTYWIVFSFLSVIEFWSKAILYLIPFYWFLKTVFLIYIALP-QTGGARMIYQKIVAP--LTDRYILRDVSKTEKDEIRASVNEASKATGASVH----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. ... . . . : :* **.: : : . : ::: .* ..:*.*: *. ***:*: .:::. . ** : * **:.:..::: **:.. : :***:: * **:: * .*: ::* ::: * * . : :.. .. ", "identical_positions": 29, "similar_positions": 66, "identity": "14.36%" }, { "cls_id": "homologset.agr.MGI:1270153", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K2F8-1", "uniprot_id": "A0A0G2K2F8_RAT", "id": "A0A0G2K2F8-1", "name": "Zinc finger protein 106", "aln": "MVRERKCILCHIVYGSKKEMDEHMRSMLHHRELENLKGRDISHECRVCRVTEVGLSAYAKHISGQSHKDNVDAQEREDDGK--EEEEEDYFDKELVQLIQERKEQSRQDKPSGNNQ-EGNSDDRQPQWRREDRIPYQDRESYNQPARHHRGPPQRDWKWEKDGFNNTRKNSFPHSLRNSGGPRGSSGWHKGATRGSSTWFHSHSNSGGGWHSNNGMVDWNYNGTGRNPGWHPEGTGGFPNWHMNNSNGNWKSNVRGTNSWNYKGPGDKFQQGRNRNSNYQMEDVTKMWSKKSNKPSKYSQERCKWPRQDRD---KAGKYRSPQEGYTSDTFPSEGLLEFN-FEQRESQTTKQTDTAVSKINGKNGTKAREKFRRWTPYPSQRTLDLQSALKEVIGNKSETIDKPLFNFSLITAGLKEP-VDKTSNPPVLKTQKEVDLGSSNHKAVSDGAALCEVARACPITEQSEPHQKSNKIPLLKSPLLPLPTPKSGPHKHNLKNRSKTNETKSFPSGDHSHLLNKSTLEGSHGSSYTSKSHGLCPRVLKGNKTASDTQKEPDEKLNSTSQKAQE-VLQCPKTLQHPLLGTPKRVENHAKES-SVEESTRDSVDIEFQAHSAEN--SGAISEPESHGIESKDVASLTTEVASCSAHTGD-KEQGSQILGTPENLSASPHNSTVHQKEAELQVTAATSPHSGLLLDLKTSLEDAQDHNLVKSDGLFETESFEGTSLDAELQKTDINNQPPGTLLPELSKLGFPASLQRDLSRHIS-LKTKTGTHLPEPNLNSARRIRNISGHRKNETEKESGLKPTLRQILNAS--RRNVNWEQVIQQVTKKKQELGKGLPRFGIEMVPLVHNEQEVLDLEEEPDLSSLEGFQWEGVSISSSSGLARKRSLSESSVVLDRAP-VYGFFTGEGAGKEKEAQQSPSPSTAS-----QKAAMYLEPEVAPLSPSV----RTGERVGTGPTQRRHSAQLPSDHIMPFMHSARDLHSQERTTPLSEH-HTQESTGEGNPLSSTASSSGHAVSSLADAATDSSCTSGTEQNDGHSIRKKRRATGDGSSPELPSLERKNKRRKIKGKKERSQVDQLLTISLREEELSKSLQCMDNKLLQARAALQTAYVEVQRLLMLKQQVTVEMSALRTHRIQILQGLQETYEPSEHPDQTPCSLIAREHRDSRSQPSVETALLPVPFFPGFLDPPPSHASLPSSGTPLQITTC-TFQAHG--TAPDSSIQIKQEPMSPEQEGNMNTVPQGSASNVSKELLQTNRVAGDSCPVYPAIPAVITS-ESTENCQEVNQDLNFSVEQGNSRSRENSPPCQSPDPPGVNK-GEGSAKGSSGSEACSSSSLRLSFTPETPAEKETQSPADQPEQQAESTLTSAETRGSKKKKKLRKKKTLRATHVPENSDTEQDVFTTKPARKVKTGKAAKGGKVTTSTWGDSQTGREQETARDEPDSESS-LEVLEVPNPQ-LEVVAIESSESGEEKPDSPSKKDTWTAVEQNSIE-PSRSGCDEVSSTSELGTRYRDGVPVSVAETQTVISSIKASKNSSEISSEPGDDDEPTEGSFEGHQAAVNAIQIFGNSLYTCSADTTVRVYNLVSRKCVGVFEGHISKVNCLLVTHTSGKNSVLYTGSSDHTIRCYNVKTRE-CMEQLQLEDRVLCLHNRWRTLYAGLANGTVVTFNIKNNKRQEIFECHGPRAVSCLATAQEGARKLLVVGSYDCTISVRDARNGLLLR-TLEGHSKTVLCMKVVNDLVFSGSSDQSVHAHNIHTGELVRIYKGHNHAVTVVNILGKVMVTACLDKFVRVYELQSHDRLQVYGGHKDMIMCMTIHKSVIYTGCYDGSIQAVRLNLMQNYRCWWHGCTLIFGVVDHLKQHLLTDHTNPNFQTLKCRWRNCDAFFTARKGSKQDVAGHIECHAEDDSKIDS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88466-1", "uniprot_id": "ZN106_MOUSE", "id": "O88466-1", "name": "Zinc finger protein 106", "aln": "MVRERKCILCHIVYGSKKEMDEHMRSMLHHRELENLKGRDISHECRVCRVTEVGLSAYAKHISGQLHKDNVDAQEREDDGK--EEEEEEYFDKELVQLIQERKEQSRQDEPPSNSQ-EVNSDDRQPQWRREDRIPYQDRESYSQPPRHHRGPPQRDWKWEKDGFNSTRKNSFPHSLRNSGGPRGSSVWHKGATRGSSTWFLNHSNSGGGWHSNNGMVDWNYNGTGRNSSWHSEGTGGFPSWHMNNSNGNWKSSVRGTNSWNYNGLGDKFQQGRNRNPNYQMEDMTKMWNKKSNKPSKYSQERCKWQRQDRD---KAAKYRSPPEGYASDTFPSEGLLEFN-FEQRESQTTKQTDTAASKINGKNGTKARDKFRRWTPYPSQKTLDLQSALKEVIGSKSDTLEKPLFNFSLITAGLRKP-VDKTSNPPVIKTQKAGPPGSPSHKAISDGTAFCEVARACSITEQSEPHQKSNKIPLLKSPLLPLPTPKSGPHKQNLKNRSKNKETKSFPSGDHSHLLNTSTLEGSHGSSYTSKSLGLCPRVLKENKTVSGTQKEPDEKLNNTSQKAQDTVLQCPKTLQNPLPTTPKRMENDAKES-SVEESAKDSLSIESQPHSAGN--SAMTSDAENHGIKSEGVASLTTEVVSCSTHTVD-KEQGSQIPGTPENLSTSPRNSTVLQKEAEVQVSAATSPHSGLLLDLKTSLEDAQDNNLVKSDGPFETESFEDTSLDTELQKPDLNNQPPGTLLPELSKLGFPASLQRDLSRHIS-LKSKTGTHLPEPNLNSARRIRNVSGHRKNETEKESGLKPTLRQILNAS--RRNVNWEQVIQQVTKKKQELGKGLPRFGIEMVPLVQNEQEVLDLDEEPDLSSLEGFQWEGVSIPSSSGLARKRSLSESSVVMDRAP-VYSFFTGEGTGKENEAQQSPSPNTALSAAQSQKTAMYLEQEVAPLTPSV----GTGERVGNIPTQRRHSAQLPSGHIMPVMHSARDLHSQERSTPLSER-HAQESTGEGNSLSSNASS-GHAVSSLADAATDSSCTSGAEQTDGHSIRKKRRATGDGSSPELPSLERKNKRRKIKGKKERSQVDQLLTISLREEELSKSLQCMDNKLLQARAALQTAYVEVQRLLVLKQQITVEMSALRTHRIQILQGLQETYEPPEHPDQAPCSLISREQRNSRSQTSFETALLPAPFFPGFLDPPPSHASLPSPGNPLQITMS-TFQAHG--TAPDSSVQIKQEPMSPEQEGNMNALPQGCASNVSKELLQTNRVVDDGSSVYPAIPAVIAS-ESTENCQEVSKDLNFSVEQGNSRSKGNSPSCQSPDLPGINR-GEETAKGSSGSEACSSSFLRLSFTPETPAEKETQSPADQPEQQAESTLASAETRGSKKKKKLRKKKTLRATHVPENSDTEQDVFTAKPARKVKTAKAAKGAKVTTS-----QTGQEQGTARDEPDSDSS-LEVLEVTNPQ-LEVVAIDTSESGDEKPDSPSKKDAWIAAEQNPIE-TSRSGCDEVSSTSELGTRYKDGVPVSVAETQTVIS-IKASKHSSEISSEPGDDEEPTEGSFEGHQAAVNAIQIFGNFLYTCSADTTVRVYNLVSRKCVGVFEGHTSKVNCLLVTHTSGKSSVLYTGSSDHTIRCYNIKTRE-CMEQLQLEDRVLCLHNRWRTLYAGLANGTVVTFDIKNNKRQEIFECHGPRAVSCLATAQEGARKLLVVGSYDCTISVRDARNGLLLR-TLEGHSKTVLCMKVVNDLVFSGSSDQSVHAHNIHTGELVRIYKGHNHAVTVVNILGKVMVTACLDKFVRVYELQSHDRLQVYGGHKDMIMCMTIHKSVIYTGCYDGSIQAVRLNLMQNYRCWWYGCTLIFGVVDHLKQHLLTDHTNPNFQTLKCRWRNCDAFFTARKGSKQDVAGHIERHAEDDSKIDS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H2Y7-1", "uniprot_id": "ZN106_HUMAN", "id": "Q9H2Y7-1", "name": "Zinc finger protein 106", "aln": "MPVGR------IECPSSPSFP-----------------RDISHECRVCGVTEVGLSAYAKHISGQLHKDNVDAQEREDDGKG-EEEEEDYFDKELIQLIKQRKEQSRQDEPSNSNQ-EINSDDRRPQWRREDRIPYQDRESYSQPAWHHRGPPQRDWKWEKDGFNNTRKNSFPHSLRNGGGPRGRSGWHKGVAGGSSTWFHNHSNSGGGWLSNSGAVDWNHNGTGRNSSWLSEGTGGFSSWHMNNSNGNWKSSVRSTNNWNYSGPGDKFQPGRNRNSNCQMEDMTMLWNKKSNKSNKYSHDRYNWQRQENDKLGTVATYRGPSEGFTSDKFPSEGLLDFN-FEQLESQTTKQADTATSKVSGKNGSAAREKPRRWTPYPSQKTLDLQSGLKDITGNKSEMIEKPLFDFSLITTGIQEPQTDETRNSPTQKTQKEIHTGSLNHKASSDSAASFEVVRQCPTAEKPEQEHTPNKMPSLKSPLLPCPATKSLSQKQDPKNISKNTKTNFFSPGEHSNPSNKPTVEDNHG-PYISKLRSSCPHVLKGNKSTFGSQKQSGDNLNDTLRKAKE-VLQCHESLQNPLLSTSKSTRNYAKASRNVEESEKGSLKIEFQVHALEDESDGETSDTEKHGTKIGTLGSATTELLSGSTRTADEKEEDDRILKTSRELSTSPCNPIVRQKESELQMTSAASPHPGLLLDLKTSLEDAQVDDSIKSHVSYETEGFESASLDAELQKSDIS-QPSGPLLPELSKLGFPASLQRDLTRHIS-LKSKTGVHLPEPNLNSARRIRNISGHRKSETEKESGLKPTLRQILNAS--RRNVNWEQVIQQVTKKKQELGKGLPRFGIEMVPLVQNEQEALDLDGEPDLSSLEGFQWEGVSISSSPGLARKRSLSESSVIMDRAPSVYSFFSEEGTGKENEPQQMVSPSNSLRAGQSQKATMHLKQEVTPRAASL----RTGERAENVATQRRHSAQLSSDHIIPLMHLAKDLNSQERSIPPSENQNSQESNGEGNCLSSSASS-ALAISSLADAATDSSCTSGAEQNDGQSIRKKRRATGDGSSPELPSLERKNKRRKIKGKKERSQVDQLLNISLREEELSKSLQCMDNNLLQARAALQTAYVEVQRLLMLKQQITMEMSALRTHRIQILQGLQETYEPSEHPDQVPCSLT-RERRNSRSQTSIDAALLPTPFFPLFLEPPSSHVSPSPTGASLQITTSPTFQTHGSVPAPDSSVQIKQEPMSPEQDENVNAVPPSSACNVSKELLEANREISDSCPVYPVITARLSLPESTESFHEPSQELKFSVEQRNTRNRENSPSSQSAGLSSINKEGEEPTKGNSGSEACTSSFLRLSFASETPLEKEPHSPADQPEQQAESTLTSAETRGSKKKKKLRKKKSLRAAHVPENSDTEQDVLTVKPVRKVKAGKLIKGGKVTTSTWEDSRTGREQESVRDEPDSDSS-LEVLEIPNPQ-LEVVAIDSSESGEEKPDSPSKKDIWNSTEQNPLE-TSRSGCDEVSSTSEIGTRYKDGIPVSVAETQTVISSIKGSKNSSEISSEPGDDDEPTEGSFEGHQAAVNAIQIFGNLLYTCSADKTVRVYNLVSRKCIGVFEGHTSKVNCLLVTQTSGKNAALYTGSSDHTIRCYNVKSRE-CVEQLQLEDRVLCLHSRWRILYAGLANGTVVTFNIKNNKRLEIFECHGPRAVSCLATAQEGARKLLVVGSYDCTISVRDARNGLLLR-TLEGHSKTILCMKVVNDLVFSGSSDQSVHAHNIHTGELVRIYKGHNHAVTVVNILGKVMVTACLDKFVRVYELQSHDRLQVYGGHKDMIMCMTIHKSMIYTGCYDGSIQAVRLNLMQNYRCWWHGCSLIFGVVDHLKQHLLTDHTNPNFQTLKCRWKNCDAFFTARKGSKQDAAGHIERHAEDDSKIDS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QN33-1", "uniprot_id": "F1QN33_DANRE", "id": "F1QN33-1", "name": "", "aln": "MVKELKCILCETVYNSKQEMEEHMRSMLHHRELENLKGRDCGHECRVCGITEVSLTDYASHISSPSHKQRVDNQKRQHLNE---DQDEEYFDKDIVRLIENRKEMIRKEEAAAKQAKEEQENIRKWQELRTRNMMYQPCGPWDRP-----------------------YSNFPQMPKRGRG----SEWQN-----------------SRFSSPECNKWFNPSRQVRCATWHAEGPPDFQKWGSYGRQG--GSLHNQGNVWGGK-------QGKYGFCPPHLRQQFPWNNSRVNVP---------WG------------QCIPSHKFFTSSTREHQKTPNR-FEN-QTQSEQSLEESGDHDPNKGKGQKAEKAYRWAPYPSAKLGDPSS-----QTNPHPPLDK---------SDVKSP-ENLNAQSYNKGSQDMERKSKSDHKRWHHKTTFYEESNSMEQKISSKNVSGCSKD--------SFSSTSTTRRTETPTKLSENCSKRPLKKAGSQDSVSSKSSKHSHSSSEIPQHG--------------SSSAQQDRLLSEMLRKAKETLLDRNTSIDTPGPDSCLIGSNNMQVE--SSELNKNQALHESKKKLQKN------RGQETHGFDRR-VSS-----------------DQEQLTSTETNIQISNVRSECRSYLQSLQVSTSTIDHE----DEEDSGEMEENPHIPVQDQVMETLD-EGLCLVGEGSHSNPSQQTASDSVPSLSTLALPACLQRDLNRHMG-TKVKAASHEP--NLNNARRVRNVSDMRKNEAEKDSGLKPTLRQLISSSGSRRNVNWDQVYQEVNRKKQ--GKGLPRFGIEMVP---CEPEGLNQMDEDDVPLSEGFHWDSL-FDSSQVPTRKRSLSESNVVKDSPAGSSSLLN----------------------------------AVVPLRDSS----ACGS------------------------------------SQPAKREELQESQGHLEFQSSKGHA-----KGVEDVEIDVDCASDTELIDTQGAGKKRRARGDVVSPEIPNEDRKNKRQKIKAKKERCQVDQLLAVSLREEELNNSLQAVDNSLIQARAALQAAYLEVQRLLMVKQQVTSEMNSLRTERIEILQGMQGEFEPKER---------HRSCEESLNTSSTQVSQITDNSVHQSSDPHSTTSSSSQPVTVKQEPVS-----------PCKPISEHNLVISPNPGAQSTASVQMTFAACQTETTTRNNSRMDTS--QDAISKAFET--STLDHRLKPSPVKEVCQSSQDGLANPSSPLMSASLS--------PKPLSPSNLSESNPVKRVRKLKKRKCLKKAKGNEQPEISESELDLEQPALRPIRKYRSHRRSSDLLTSPPTPEKKDKNEEMVVTEASKPQP----QGIKLAKP-------------PLNEANSDSSDLEIVELPPPVPTDFVNLDSSDPEEMPEKAAKEPATMHKIENQAITDPQNLACNEVTSTSEIGTR---SIVKAIESEKKSASAMLESKVPSDMS-DPGEEELPTEGDFEGHQEAVNGMHIHNGLLYTCSGDRTIRAFSLITRKCVAVFEGHSSKVNCLLVSCGGGLQQRLYSGSSDQTIRCYSLKTKE-CVEQLSLPDRVLCLHNRWKILYIGLANGSVITLSLRNNKQLDVFECHGPRAVSCLATAQEGARRILLVGSYDTTISVRDAKSGLLLR-TLEGHTKTVLCMKVVNDLVFSGSSDQSVHAHNIHTGELVRIYKGHSHAVTVVAILGKVMVTACLDKLVRVYELQSHDRLQVYGGHSDMVMCMVIHKSMIYTGCYDGSVKAVRLNLIQNHRCWWHGCTLIFGVMEHLQQHLLNDHTSPAQQTFKCRWRNCDSFFTTRNSSKEAVHCHMQKHAEDDSKMEP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KHA8-1", "uniprot_id": "A0A0B4KHA8_DROME", "id": "A0A0B4KHA8-1", "name": "Zinc finger protein 106", "aln": "-----------------MSAPQQQRGESGGGAPPDTGRDSASQPAKSSTASGSGHSATCSHSPSSKNRRQNNSMKYNSRPWQRGRSDSGHFNNRVHSNHNQRQTPYPKSNYENRGRSDTRSSNQERQERD-----YTKRTDFRER-----------------------NTRFSDERHSGRY--------------------------SDYHRRNHYHRFKSWGSEGRSYRRDKGARDLSKSRYDNDASG-SSLIRGASEIRRK-------NGHNCDPNSDASKTENSEDIQSCIN----------------------HYQTEENKIDTEQSKDQGANRTSPTEQLSDISKQSNPIALEGDQNKKTNELKESSCSSKPSREINETSKASQFPDQRSKEQ-------------SSGEELNVSESSDNHSGAQASQSIPRIQVRPLTKLLRQELFAVTQENRLIKSPPPSAS-------------PASPSRLVFTPNLRNRRRTVSNCIYNAGSFDQTAESEAVFNDRIASMDKESLKYIINNGDTIFEPHLQLQARRRIRDEIRRQLKTIELEKPKDCLVTDLVEDEIVDSIKLPAFLLEEIGKCFGIDISEGQTTKD------SAAEREDTTRVNAESP---------------VQDTEEETKRACNGVESLKDIKTEATADDSNQCTKFRNLENEIDINDNHHQSEDDELSKPLSVLPKDSEDCSVKSNGVSKKVLQENNKKKTFNRDTKVNGNKAMNPPQETVIETLEHSDSINRSITNPKTADELKSFAGIEWEVNSKSKHSNPSQSAFIKTN--KSNNIETALIDSLSGISKPCKMEIKRE---------SSSSPISVSSLPSNDVIDLLSSSDEELEEHAVVDMDIDEHEGDIENQKIFKTLEALKQS-------------------------------DDVVDSDDSTSSQS---------------------------------------SSKSTKRRRRLKLQNDAENVVDSFEK-------LILPHLREALSDRYRRQHSSSLQSRLHFISCVVTSSEHNAQTFSKIEVAKMQMNLKAADNRQAIEFLLKEIVNVVSLQKQRRREQDEEQKLANLLSPKKTAFTSDETCKASTLCPNQHGFIPPTAQDSSPVTSPCQKPPSSPPSQQSPSSATAQQSSPMALQKTQSCPARQSSTSIQENPMDSSGQWRGSASHKTQSSPARQTTPVGDVFENPSPNQ-GNPPSSAKLESFNVGFPFLSMDPTLYNYSRLASGSKINEPLGKSDDMMEQHLVEIERELIKHENRYSFLDDIIIKFQKEKSEVGMVILELKSRKFLIINSMASRNQATSAQVADSKSKPHEAETAQESTHEDSFSKGGIARRTRSRLRRTVLVLAPKRQVRVQKRVSKKPKSFKLVEKSHEEIAEQETN----------------KMDSKATNQLNINEELLKVSAGDQVSDYSPTAKLAQSRLSKPSIAVNPTHQPLAIIPPLPPPPPPPEPICHMSYEASSSFLKEPLHEPGHQLSELN-----SEDKTRQGFVTKGKLQNVGSPITQIKIYRDNVIAAAEDGDIYVFHLVTHKLEQKITKHSEAITNMFLSE---KDSILYTTSADGFFKKSSLLNLERVFETVYLKEPLQSMDVAWGLAFIGSRWGQISTFNVVTNKVVEKPLVSTGQSIIAIKATKEGVRKILVLGCKGNFVQMHDAGNGLLLRHVFIAEGLNIYSLLLDEGHIYCGTQKNELYQLEFVSGNLVTKFSCGNGAVAVAAYGERYLLVGCYDGYIYVLNKITGTQTGRFAGAGRMVLALSVVGDKIVTSSKDNSLAILEVPPALVNGY--------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . .: .: . : . : ..* .. :: . : : : .:. :*:: : ::*: :.: : ... :. * * : . . *.. : . . : . :: . :*. .: . . . * . . . *: . . . : . :. .. *: . : :. : . .* :. * . . . * . :. . : . : :.. . . .. .:.. . : .. .. . .. .. : .: . : .. :: : *: . . .* : : : : * .. * : . . . . . . . : : * : . . : . . . : .: . : . :.: .:: : : . . : . * :.* .::..:. . . .*.. :*: ::.:. : * : :.:. .: : * . . :. . : : .. : . . . *..: : :. *. * ::. . : .. : .. : :. . . . .: : . :.. . : .* . * : : .*: :.: :*: : :. .: : : * : : ...: * : .:* ..: :: .* . * .. . . .: . * . ..: **: : : : : . * . :: . : . . . .. * .:.: .:: . :: :. : . * : :. . : . : :. . .. :. *:: * : * . . . .: ::.: .. . . : : : * : : *:*.::. .:. ::*. . : :.: * : .: *:::* : * . :. :::: . **: *:* :: .: . * .* : * : : .:. * : * * : *:.: .** : ::: .: :::**.*::*::*. . :.::** .***** .: .. .: .: : :. ::.*:..:.:: :: :*:** :. . **:*. : ::..* * : * : : : :.* *::.: : . * *.. *.*: :.: ", "identical_positions": 94, "similar_positions": 480, "identity": "4.88%" }, { "cls_id": "homologset.agr.MGI:1270156", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A096MJN4-1", "uniprot_id": "SEPT4_RAT", "id": "A0A096MJN4-1", "name": "Septin-4", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MIKHFLEDNSDDAELSKFVKDFPGSEPCHPTESKTRVARPQILEPRPQSPDLCDDDVEFRATLWS------QPSDSQQYFCPPAPLSPSSRPRSPWGKLDPYDSSED-DKEYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVNSLFLTDLYRDRKLLGAEERIMQT---------------------VEITKHAVDIEEKGVRLRLTIVDTPGFGDAVNN-TECWRPVAEYIDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRPLDVEFMKALHQRVNIVPILAKADTLTPSEVDRKKCKIREEIEHFGIKIYQFPDCDSDEDEDFKLQDQALKESIPFAVIGSNTVVE-ARGRRVRGRLYPWGIVEVENPGHCDFVKLRTMLVRTHMQDLKDVTRETHYENYRAQCIQSMTR----LVVKERNR--NKLTRESGTDFPIPAVPPGTDPETEKLIREKDEELRRMQEMLHKIQRQMKETH---------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P28661-1", "uniprot_id": "SEPT4_MOUSE", "id": "P28661-1", "name": "Septin-4", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDHSLGWQGNSVPEDGT------------------------------------------------EAGIKHFLEDSSDDAELSKFVKDFPGSEPYHSAESKTRVARPQILEPRPQSPDLCDDDVEFRGSLWP------QPSDSQQYFSAPAPLSPSSRPRSPWGKLDPYDSSED-DKEYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVNSLFLTDLYRDRKLLGAEERIMQT---------------------VEITKHAVDIEEKGVRLRLTIVDTPGFGDAVNN-TECWKPVAEYIDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRPLDVEFMKALHQRVNIVPILAKADTLTPPEVDRKKCKIREEIEHFGIKIYQFPDCDSDEDEDFKLQDQALKESIPFAVIGSNTVVE-ARGRRVRGRLYPWGIVEVENPGHCDFVKLRTMLVRTHMQDLKDVTRETHYENYRAQCIQSMTR----LVVKERNR--NKLTRESGTDFPIPAVPPGTDPETEKLIREKDEELRRMQEMLHKIQRQMKETH---------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43236-7", "uniprot_id": "SEPT4_HUMAN", "id": "O43236-7", "name": "Septin-4", "aln": "MVKTNKPGAKVAVSAQRGSEVTTNTSPQQGHGYVLASSHRSAAVSLNPSHRRSEAAHPTTPHSASDYPRSVSLQSGPGHYAVPTPRGPETGPRTESSRHSSPHLKSQKTQTLASHASSRQWKVSPPREEAARRGSESKSGREVGHHASSIPDAKSTHQLSFQDQKNNLQSQILEDDPPSKVQNPQGVRVPRRILSYPKDEAVQTEPIQRITTTSEIRSPRSPSLLEHGSSCVSADYQTAQRRVPVEESETGPYGPIPSKPKALYRNMNLDSLLKLSVLKDSDGVHRVSARVDPESLHKYSAYPETKPSAKVLVSSQVESNVRTPIRGNSEVGRRVTISPGVQSVEPTHHVTVPSVSEGSHKSSMFVTPEPIYKQQTQKPPEITYMSQGPTPRYPELSQKPSIHAELELTPRPLPPRSLPRYGPDSSWWPLLNPEVETPQSQLTTPDFEPKCSPSLDLLLSGFKIDSSPFCEDLKFQREKASLSPPSPPKEFPSWAPLSEVPQTPKHTCKQPIQRFTAFFLDVSEEMYNRVIWWLKDEEIKRFLEDTTDDGELSKFVKDFSGNASCHPPEAKTWASRPQVPEPRPQAPDLYDDDLEFRPPSRP------QSSDNQQYFCAPAPLSPSARPRSPWGKLDPYDSSED-DKEYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVNSLFLTDLYRDRKLLGAEERIMQT---------------------VEITKHAVDIEEKGVRLRLTIVDTPGFGDAVNN-TECWKPVAEYIDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRPLDVEFMKALHQRVNIVPILAKADTLTPPEVDHKKRKIREEIEHFGIKIYQFPDCDSDEDEDFKLQDQALKESIPFAVIGSNTVVE-ARGRRVRGRLYPWGIVEVENPGHCDFVKLRTMLVRTHMQDLKDVTRETHYENYRAQCIQSMTR----LVVKERNR--NKLTRESGTDFPIPAVPPGTDPETEKLIREKDEELRRMQEMLHKIQKQMKENY---------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N7Z7-1", "uniprot_id": "A0A8M1N7Z7_DANRE", "id": "A0A8M1N7Z7-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPCTGS--------------------------------------------------ALSSLAIEDCEDAELAYTMRDLPPRAAHTFPENQTMDRQPDG-STAPHTPGTPTTTRPINRSFLGSEQELFRRGQLSSVSSLDSPLSPS-RPKSPWARFDPYDSAEDQDKEYVGFATLPNQVHRKSVKKGFAFTLMVAGESGLGKSTLVNSLFLTDLYKDRKMPNAEERIAQT---------------------VEITKHTVAIEEKGVKLRLTIVDTPGFGDAVNN-TESWRAIVDYIDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRPIDVEFMKILHEKVNIVPVLAKTDSLTPEEVRKMKMKIREEIERFDIMIYQFPECESDEEDEFKLQQQELKDSVPFAVIGSNVQVE-SQGRRFRGRQYPWGLVEVENPEHSDFLKLRNMLVRTHMQDLKDVTRETHYENYRAQCIQNMTR----MVVRERKRSLNSRLRESPSDLPVPLVP--VDTETERLIWEKDEELRRMQEVLERIQEQMRQGHEDLPIN---------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q0KHR7-1", "uniprot_id": "Q0KHR7_DROME", "id": "Q0KHR7-1", "name": "Septin", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKHQPPPPPLPLSQPPTMG--------ATAAGGVASVISTMNGSSSS---------GIEAVKCRP-PIYPK--PKTP---------SFDKDRDYIGFATLPEQVHRKSVKRGFEFTLMVVGESGLGKSTLINSLFLGDLYKNRQMPNVEERIEKT---------------------TKVEKKTMDIEERGVRLRLTVVDTPGFGDAINC-EDSWRVCTQYIDEQFRQYFTDESGLNRRNIQDNRVHCCLYFVPPWGHSLRQMDLDLIRRLHRKVNIVLVIGKADCLNKQEVRKLKERILQDLEDNHIQLYQFPECDSDEDDDFKQQDRELKASIPFAVVGSNTILE-VAGKKVRGRQYPWGVVNVEDPEHSDFIKLRTFLISTHMQDLKDTTQDVHYENFRAQCISQISQ----HALRERGK--LKRDSISSTNGFDAAIS-----ETDRLLLQKDEEIRRMQDMLTQMQEKLKQTHLMEMKKNDSVIDV--------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32457-1", "uniprot_id": "CDC3_YEAST", "id": "P32457-1", "name": "Cell division control protein 3", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSLKEEQVSIKQDPEQEERQHDQFNDVQIKQESQDHDGVDSQYTNGTQNDDSERFEAAESDVKVEP---------GLGMGITSSQSEKGQVLPDQP-----EIKFIRRQINGYVGFANLPKQWHRRSIKNGFSFNLLCVGPDGIGKTTLMKTLFNNDDIEANLVKDYEEELANDQEEEEGQGEGHENQSQEQRHKVKIKSYESVIEENGVKLNLNVIDTEGFGDFLNNDQKSWDPIIKEIDSRFDQYLDAENKINRHSINDKRIHACLYFIEPTGHYLKPLDLKFMQSVYEKCNLIPVIAKSDILTDEEILSFKKTIMNQLIQSNIELFKPPIYSNDDAENSHLSER-LFSSLPYAVIGSNDIVENYSGNQVRGRSYPWGVIEVDNDNHSDFNLLKNLLIKQFMEELKERTSKILYENYRSSKLAKLGIKQDNSVFKEFDPISKQQEEKTLHEAKLAKLEIEMKTVFQQKVSEKEKKLQKSETELFARHKEMKEKLTKQLKALEDKKKQLELSINSASPNVNHSPVPTKKKGFLR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. . . . . * * . *:***.**:* **:*:*.** *.*: .* .*:**:**:::** * . . : . **.: : .:: . ***.**:*.*.::** **** :* ..* . **.:* **: *. :**:.*:*:*:*.****: * ** *: :*:.::: ::.: *:: ::.*:* *. *: * * ::: * ::: * ..*: :: : .:: * *:*:**:*** :* *.:.*** ****:::*:: *.** *:.:*: .*::**: * . ***:*:. : .: ..:* . : : . : :: : :*:::::: : * :.:::: ", "identical_positions": 108, "similar_positions": 142, "identity": "10.08%" }, { "cls_id": "homologset.agr.MGI:1270158", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A7B5-1", "uniprot_id": "D4A7B5_RAT", "id": "D4A7B5-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASSGRLGFTVRSLLNLP--------------------------------------------------------------------EQDAQPRVRCEQQTCVPQT---------------------------------------------------------------------------------------------------AAWLESE-------------------------------------------------------------------------------------------------------RSHYPSSDESGLETSPADSSQL-ASLGRASPGSD--AEKRRKRRVLFSKAQTLELERRFRQQRYLSAPEREQLARLLRLTPTQVKIWFQNHRYKLKRGRAP-GVTESSDVTASADLH----AAPGLLRRVVVPVLVHDRSPCN---------------------GRGEGTAAVPQDKCSSRLATACPVQGYTAFGPGSALGLFPAYQHLAPPALVSWNW---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70584-1", "uniprot_id": "NKX28_MOUSE", "id": "O70584-1", "name": "Homeobox protein Nkx-2.8", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MATSGRLGFTVRSLLNLP--------------------------------------------------------------------EQDAKPRVRREQQTCVPQT---------------------------------------------------------------------------------------------------AAWLESE-------------------------------------------------------------------------------------------------------CSHYLSSDESGLETSPADSSQL-ASLRRESPGSD--PEKRRKRRVLFSKAQTLELERRFRQQRYLSAPEREQLARLLRLTPTQVKIWFQNHRYKLKRGRAP-GITEPSDMAASSDLH----AAPGLLRRVVVPVLVHDRPPSNN--------------------GRGEGTSAVPQDKCSARLATACPVPGYTAFGPGSALGLFPAYQHLAPPALVSWNW---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15522-1", "uniprot_id": "NKX28_HUMAN", "id": "O15522-1", "name": "Homeobox protein Nkx-2.8", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MATSGRLSFTVRSLLDLP--------------------------------------------------------------------EQDAQHLPRREPEPRAPQPDP------------------------------------------------------------------------------------------------CAAWLDSE-------------------------------------------------------------------------------------------------------RGHYPSSDESSLETSPPDSSQR-PSARPASPGSD--AEKRKKRRVLFSKAQTLELERRFRQQRYLSAPEREQLASLLRLTPTQVKIWFQNHRYKLKRARAP-GAAESPDLAASAELH----AAPGLLRRVVVPVLVRDGQPCGGG-------------------GGGEVGTAAAQEKCGAPPAAACPLPGYPAFGPGSALGLFPAYQHLASPALVSWNW---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9P8T3-1", "uniprot_id": "A0A8M9P8T3_DANRE", "id": "A0A8M9P8T3-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAISNKFSFTVRSILDLP--------------------------------------------------------------------ENDTESIVQHSPLDSFSVS-P------------------------------------------------------------------------------------------------YSTWTEND-------------------------------------------------------------------------------------------------------RGH-ISSDDSNIEASP-DSTEP-DVL---SVDTE--HEKRKKRRVLFSKAQTYELERRFRQQRYLSAPEREQLAHLLRLTPTQVKIWFQNHRYKMKRAR----------IECAQDLN----QPP-VLRRVVVPILVRDGKPYQNCT-----------------IDTEKGNGIVPP----TVPSSPFTVQGFHSLQQQTPFALFPTYQHFTNTAASRHHFCVW", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P22808-1", "uniprot_id": "VND_DROME", "id": "P22808-1", "name": "Homeobox protein vnd", "aln": "MTTSASLERTPSKRDRDRERDNSSGLGSAGSLPASPQSAITVSPSSPATPKRPLRTSTPSLERKREREDREDREDRKERQERHERDRDHERFAAVFSTASTTVPTNTSSSSGLAPEQLRIPTGAAAFSGFPGLHSMSSLMLPSSAAVAAAAAAPFLPWSPILLPPWNHALLPAAFYPAALRNALPGLFDAKVPSSQRSGFHISDILNLEGSELKNAAAAAAAAAHHGSDLSHHSASESTSGHRGQGSHTSPSALSPTPAGVSADEHHNGSGTGGGAGEADHHSTTEHHAPPSHPQQQHPHHQQHHHPHLLLPQQHHQQAVAPLPLAHHQSGEAQSHAHANAAAAHLLASHNAAAAAAVAAGQYLPNLPKNFPGSFGDEMSSYHHMAQTMLQHSGRSAWIKENELYGTQQPASPDSTSPVTSEVSYTYIGSNCQTSPALSGDYKSYSRSADSDALSVGDALHTLHGSSGNGSAGGAPTAHALHNNNNNTTNNNNHSLKAEGINGAGSGHDDSLNEDGIEEDIDDVDDADGSGGGDANGSDGLPNKKRKRRVLFTKAQTYELERRFRQQRYLSAPEREHLASLIRLTPTQVKIWFQNHRYKTKRAQNEKGYEGHPGLLHGHATHPHHPSALPSPRRVAVPVLVRNGKPCLGDSSKLGADCVSVSSATATAMQNAAAHHLVALNGAAAYQHAAAAAAGLHAHAHAHAHAHGHGHPHAHAQRAAWWP----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. * : .* : .:*:* * * . . . ::* ..: .* * ::..:* . * : : .:: :*::******:**** ******************:** *:***************** **.: : . : . ***.**:**:: * .. : :. . * : . . : * ", "identical_positions": 72, "similar_positions": 54, "identity": "9.9%" }, { "cls_id": "homologset.agr.MGI:1270839", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AYK6-1", "uniprot_id": "CYBP_RAT", "id": "Q6AYK6-1", "name": "Calcyclin-binding protein", "aln": "MASALEELQKDLEEVKVLLEKSTRKRLRDTLTNEKSKIETELRNKMQQKSQKKPE-FDNEKPAAVVAPLTTGYTVKISNYGWDQSDKFVKIYITLTGVHQVPAENVQVHFTERSFDLLVKNLNGKNYSMIVNNLLKPISVESSSKKVKTDTVIILCRKKAENTRWDYLTQVEKECKEKEKPSYDTEAD-PSEGLMNVLKKIYEDGDDDMKRTINKAWVESREKQAR-EDT-----EF---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CXW3-1", "uniprot_id": "CYBP_MOUSE", "id": "Q9CXW3-1", "name": "Calcyclin-binding protein", "aln": "MASVLEELQKDLEEVKVLLEKSTRKRLRDTLTSEKSKIETELKNKMQQKSQKKPE-LDNEKPAAVVAPLTTGYTVKISNYGWDQSDKFVKIYITLTGVHQVPTENVQVHFTERSFDLLVKNLNGKNYSMIVNNLLKPISVESSSKKVKTDTVIILCRKKAENTRWDYLTQVEKECKEKEKPSYDTEAD-PSEGLMNVLKKIYEDGDDDMKRTINKAWVESREKQAR-EDT-----EF---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HB71-1", "uniprot_id": "CYBP_HUMAN", "id": "Q9HB71-1", "name": "Calcyclin-binding protein", "aln": "MAS--EELQKDLEEVKVLLEKATRKRVRDALTAEKSKIETEIKNKMQQKSQKKAELLDNEKPAAVVAPITTGYTVKISNYGWDQSDKFVKIYITLTGVHQVPTENVQVHFTERSFDLLVKNLNGKSYSMIVNNLLKPISVEGSSKKVKTDTVLILCRKKVENTRWDYLTQVEKECKEKEKPSYDTETD-PSEGLMNVLKKIYEDGDDDMKRTINKAWVESREKQAK-GDT-----EF---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W3Y3-1", "uniprot_id": "Q9W3Y3_DROME", "id": "Q9W3Y3-1", "name": "Calcyclin-binding protein", "aln": "--MSLEQLKSDVAELAAFLQQAKGARVKDVLTTAKAEAEREIVN-LELKAKIAAE------RQATGSSEAKRYLHELTDYGWDQSAKFVKLFITLNGVQGCTEENVTVTYTPNSLQLHVRDLQGKDFGLTVNNLLHSIDVEKSYRKIKTDMVAIYL-QKVEDKHWDVLTAIQKRLKQKKDSELSKDGDNPESALVNIMKKMYNDGDSKTKQMIAKAWTESQDKAKLGKETGGGLDSFDDL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:*:.*: *: .:*:::. *::*.** *:: * *: * :: *:: .* *. :. :. * ::::****** ****::***.**: . *** * :* .*::* *::*:**.:.: *****:.*.** * :*:*** * * :*.*:.:** ** ::*. *:*:... ..: * *...*:*::**:*:***.. *: * ***.**::* :* .* ", "identical_positions": 87, "similar_positions": 84, "identity": "36.25%" }, { "cls_id": "homologset.agr.MGI:1270840", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B2RYD8-1", "uniprot_id": "B2RYD8_RAT", "id": "B2RYD8-1", "name": "ETS homologous factor", "aln": "-------------MILEGSGVMNLNPANNLLHQPPA-WTDSYSACNVS---SGFFGGQW-HEIHPQYWTKYQVWEWLQHLLDTNQLDASCIPFQEFDISGEHLCSMSLQEFTRAAGSAGQLLYSNLQHLKWNGQCSSDLFQSAHNVIVKTEQTDPSIMNTWKEENYLYDPSYGSTVDLLDSKTFCRAQISMTTSSHLPVAESPDMKKEQDHPVKSHTKKHNPRGTHLWEFIRDILLSPDKNPGLIKWEDRSEGIFRFLKSEAVAQLWGKKKNNSSMTYEKLSRAMRYYYKREILERVDGRRLVYKFGKNARGWRENEN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70273-1", "uniprot_id": "EHF_MOUSE", "id": "O70273-1", "name": "ETS homologous factor", "aln": "-------------MILEGSGVMNLNPANNLLHQQPA-WTDSYPTCNVS---SGFFGSQW-HEIHPQYWTKYQVWEWLQHLLDTNQLDASCIPFQEFDISGEHLCSMSLQEFTRAAGSAGQLLYSNLQHLKWNGQCSSDLFQSAHNVIVKTEQTDPSIMNTWKEENYLYDPSYGSTVDLLDSKTFCRAQISMTTSSHLPVAESPDMKKEQDHPVKSHTKKHNPRGTHLWEFIRDILLSPDKNPGLIKWEDRSEGIFRFLKSEAVAQLWGKKKNNSSMTYEKLSRAMRYYYKREILERVDGRRLVYKFGKNARGWRENEN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NZC4-1", "uniprot_id": "EHF_HUMAN", "id": "Q9NZC4-1", "name": "ETS homologous factor", "aln": "-------------MILEGGGVMNLNPGNNLLHQPPA-WTDSYSTCNVS---SGFFGGQW-HEIHPQYWTKYQVWEWLQHLLDTNQLDANCIPFQEFDINGEHLCSMSLQEFTRAAGTAGQLLYSNLQHLKWNGQCSSDLFQSTHNVIVKTEQTEPSIMNTWKDENYLYDTNYGSTVDLLDSKTFCRAQISMTTTSHLPVAESPDMKKEQDPPAKCHTKKHNPRGTHLWEFIRDILLNPDKNPGLIKWEDRSEGVFRFLKSEAVAQLWGKKKNNSSMTYEKLSRAMRYYYKREILERVDGRRLVYKFGKNARGWRENEN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TDV0-1", "uniprot_id": "A0AB32TDV0_DANRE", "id": "A0AB32TDV0-1", "name": "ETS homologous factor", "aln": "MSVISSTYVQHWIMVLQASGVMSIPATVSVDNQLPASWTTHYNCTDVSMMTSNFTSRLWTQDPHPQNWTKFQVWEWLQQTLDMHQIDATSIPFQNFDLDGRQLCNMSFQDFTRAAGSVGSILFQSLTDLKWNGQYGQTDMFTPADIKTEIDADFPCSILPFKEE-----SSFYSNPELFDIKSSFQPSSILPS----PAPSSPDPKRSQ-------VKRHNPRGTHLWEFIRDILLNPERNPGLIKWEDRSEGVFRFLKSEAVAQLWGKKKNNSSMTYEKLSRAMRYYYKREILERVDGRRLVYKFGRNARGWRESEK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:*:..***.: . .: :* ** ** * :** *.* . * :: *** ***:*******: ** :*:**..****:**:.*.:**.**:*:******:.*.:*:..* .****** .. : :. :: .: : *. : .:*:* ..: *. :*:* *: :.. :.: *...*** *:.* .*:*****************.*::*************:*****************************************************:*******.*:", "identical_positions": 167, "similar_positions": 79, "identity": "52.52%" }, { "cls_id": "homologset.agr.MGI:1270841", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97784-1", "uniprot_id": "CRY1_MOUSE", "id": "P97784-1", "name": "Cryptochrome-1", "aln": "------------------------------------------------------------------------MGVNAVHWFRKGLRLHDNPALKECIQGADT---------IRCVYILDPWFAGSSNVGINRWRFLLQCLEDLDANLRKLNSRLFVIRGQP-------ADVFPRLFKEWNITKLS-----IEYDSEPFGKERDAAIKKLATEAGVEVIVRISHTLYDLDKIIELNGGQPPLTYKRFQTLVSKMEPLEMPADTITSDVIGKCMTPLSDDHDEK----YGVPSLEELGFDTDGLSSAVWPGGETEALTRLERHLERKAWVANFERPRMNANSLLASPTGLSPYLRFGCLSCRLFYFKLTD-----LYKKVKKNSSPPLSLYGQLLWREFFYTAATNNPRFDK-MEGNPICVQIPWDKNPEALAKWAEGRTGFPWIDAIMTQLRQEGWIHHLARHAVACFLTRGDLWISWEEGMKVFEELLLDADWSINAGSWMWLSCSSFFQQ-FFHCYCPVGFGRRTDPNGDYIRRYLPVLRGFPAKYIYDPWNAPEGIQKVAKCLIGVNYPKPMVNHAEASRLNIERMKQIYQQLSRYRGLGLLASVPSNSNGNGGLMGYAPGENVPSCSSSGNGGLMGYAPGENVPSCSGGNCSQGSGILHYAHGDSQQTHSLKQGRSSAGTGLSSGKRPSQ---EEDAQSVGPKVQRQSSN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q32Q86-1", "uniprot_id": "CRY1_RAT", "id": "Q32Q86-1", "name": "Cryptochrome-1", "aln": "------------------------------------------------------------------------MGVNAVHWFRKGLRLHDNPALKECIQGADT---------IRCVYILDPWFAGSSNVGINRWRFLLQCLEDLDANLRKLNSRLFVIRGQP-------ADVFPRLFKEWNITKLS-----IEYDSEPFGKERDAAIKKLATEAGVEVIVRISHTLYDLDKIIELNGGQPPLTYKRFQTLVSKMEPLEMPADTITSDVIGKCTTPLSDDHDEK----YGVPSLEELGFDTDGLSSAVWPGGETEALTRLERHLERKAWVANFERPRMNANSLLASPTGLSPYLRFGCLSCRLFYFKLTD-----LYKKVKKNSSPPLSLYGQLLWREFFYTAATNNPRFDK-MEGNPICVQIPWDKNPEALAKWAEGRTGFPWIDAIMTQLRQEGWIHHLARHAVACFLTRGDLWISWEEGMKVFEELLLDADWSINAGSWMWLSCSSFFQQ-FFHCYCPVGFGRRTDPNGDYIRRYLPVLRGFPAKYIYDPWNAPEGIQKVAKCLIGVNYPKPMVNHAEASRLNIERMKQIYQQLSRYRGLGLLASVPSNPNGNGGLMGYAPGENVP---SGGSG---------------GGNCSQGSGILHYAHGDSQQTNPLKQGRSSMGTGLSSGKRPSQ---EEDAQSVGPKVQRQSSN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q16526-1", "uniprot_id": "CRY1_HUMAN", "id": "Q16526-1", "name": "Cryptochrome-1", "aln": "------------------------------------------------------------------------MGVNAVHWFRKGLRLHDNPALKECIQGADT---------IRCVYILDPWFAGSSNVGINRWRFLLQCLEDLDANLRKLNSRLFVIRGQP-------ADVFPRLFKEWNITKLS-----IEYDSEPFGKERDAAIKKLATEAGVEVIVRISHTLYDLDKIIELNGGQPPLTYKRFQTLISKMEPLEIPVETITSEVIEKCTTPLSDDHDEK----YGVPSLEELGFDTDGLSSAVWPGGETEALTRLERHLERKAWVANFERPRMNANSLLASPTGLSPYLRFGCLSCRLFYFKLTD-----LYKKVKKNSSPPLSLYGQLLWREFFYTAATNNPRFDK-MEGNPICVQIPWDKNPEALAKWAEGRTGFPWIDAIMTQLRQEGWIHHLARHAVACFLTRGDLWISWEEGMKVFEELLLDADWSINAGSWMWLSCSSFFQQ-FFHCYCPVGFGRRTDPNGDYIRRYLPVLRGFPAKYIYDPWNAPEGIQKVAKCLIGVNYPKPMVNHAEASRLNIERMKQIYQQLSRYRGLGLLASVPSNPNGNGGFMGYS-AENIP----GCSS---------------SGSCSQGSGILHYAHGDSQQTHLLKQGRSSMGTGLSGGKRPSQ---EEDTQSIGPKVQRQSTN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N1TWC6-1", "uniprot_id": "A0A8N1TWC6_DANRE", "id": "A0A8N1TWC6-1", "name": "Cryptochrome-1", "aln": "------------------------------------------------------------------------MVVNTVHWFRKGLRLHDNPSLRDSIKGADN---------LRCVYILDPWFAGSSNVGISRWRFLLQCLEDLDASLRKLNSRLFVIRGQP-------TDVFPRLFKEWKISRLS-----YEYDSEPFGKDRDAAIRKLATEAGVEVFVRISHTLYDLDKIIEFNGGQSPLTYKRFQTLISRMDPVEMPAETITAEIMGKCSTPVSDDHDDK----FGVPSLEELGFETEGLSTAVWPGGETEALTRLERHLERKAWVANFERPRMNANSLLASPTGLSPYLRFGCLSCRLFYFKLTD-----LYRKVKKNSTPSLSLYGQLLWREFFYTAATNNPHFDK-MEFNPICVQIPWDRNPEALAKWAEGQTGFPWIDAIMTQLRQEGWIHHLARHAVACFLTRGDLWISWEEGMKVFEELLLDADWSVNAGSWMWLSCSSFFQQ-FFHCYCPVGFGRRTDPNGDYIRRYLPILRGFPAKFIYDPWNAPESVQKVAKCIIGVHYPKPMVNHAEASRINIERMKQIYQQLSCYRGLGLLATVPSNTANNEDSNGAGPSSGDT---QERTHITVHTLPASSQSEFPAFAVSCGQQLVNSVQPQPGYSGAGMVGQAHKQTQRVRGMTAFKRHGEDRTTDFPSKIQRNDCN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q0E8P0-1", "uniprot_id": "Q0E8P0_DROME", "id": "Q0E8P0-1", "name": "", "aln": "---------------------------------------------------------------------MDSQRSTLVHWFRKGLRLHDNPALSHIFTAANAAP---GKYFVRPIFILDPGILDWMQVGANRWRFLQQTLEDLDNQLRKLNSRLFVVRGKP-------AEVFPRIFKSWRVEMLT-----FETDIEPYSVTRDAAVQKLAKAEGVRVETHCSHTIYNPELVIAKNLGKAPITYQKFLGIV---EQLKVPKVLGVPEKLKNMPTPPKDEVEQKDSAAYDCPTMKQLVKRPEELGPNKFPGGETEALRRMEESLKDEIWVARFEKPNTAPNSLEPSTTVLSPYLKFGCLSARLFNQKLKE-----IIKRQPKHSQPPVSLIGQLMWREFYYTVAAAEPNFDR-MLGNVYCMQIPWQEHPDHLEAWTHGRTGYPFIDAIMRQLRQEGWIHHLARHAVACFLTRGDLWISWEEGQRVFEQLLLDQDWALNAGNWMWLSASAFFHQ-YFRVYSPVAFGKKTDPQGHYIRKYVPELSKYPAGCIYEPWKASLVDQRAYGCVLGTDYPHRIVKHEVVHKENIKRMGAAYKVNREVR-----------------------------------------------------------------TGKEEESSFEEKSETST-----SGKRKVR-----RATGSAPKRKR----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P05066-1", "uniprot_id": "PHR_YEAST", "id": "P05066-1", "name": "Deoxyribodipyrimidine photo-lyase, mitochondrial", "aln": "MKRTVISSSNAYASKRSRLDIEHDFEQYHSLNKKYYPRPITRTGANQFNNKSRAKPMEIVEKLQKKQKTSFENVSTVMHWFRNDLRLYDNVGLYKSVALFQQLRQKNAKAKLYAVYVINEDDWRAHMDSGWKLMFIMGALKNLQQSLAELHIPLLLWEFHTPKSTLSNSKEFVEFFKEKCMNVSSGTGTIITANIEYQTDELYRDIRLLENEDHRLQLKYYHDSCIVAPGLITTDRGTNYSVFTPWYKKWVLYVNNYKKSTSEICHLHIIEPLKYNETFELKP---FQYSLPDEFLQYIPKSKWCLPDVSEEAALSRLKDFLGTKSSKYNNEK----DMLYLGGTSGLSVYITTGRISTRLIVNQAFQSCNGQIMSKALKDNSSTQNFIKEVAWRDFYRHCMCNWPYTSMGMPYRLDTLDIKWENNPVAFEKWCTGNTGIPIVDAIMRKLLYTGYINNRSRMITASFLSK-NLLIDWRWGERWFMKHLIDGDSSSNVGGWGFCSSTGIDAQPYFRVFNMDIQAKKYDPQMIFVKQWVPELISSENKRPE-------------------NYPKPLVDLKHSRERALKVYKDAM-------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :****:.***:** .* . . : : ::::: . : *: *::*: .* :*: *:: . :. :. * .:**. : : : * :: * . .: :* : * .: : . .: : * : . .:: .* ** *:: * : . *: ..: ** *: * :* **: : : : : *.. .. .: :: **:*: * . * . ::* *:.:* : * *.** * :**** :* *:*:: :* .*.**:: :* *.*. * : * : *:* * : *.*.* : *.:.: * :*: : .:: **: ::::::* * .**: :*. . :: ", "identical_positions": 83, "similar_positions": 135, "identity": "11.64%" }, { "cls_id": "homologset.agr.MGI:1270843", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZRD3-1", "uniprot_id": "D3ZRD3_RAT", "id": "D3ZRD3-1", "name": "Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta", "aln": "MSAKDERARD-ILRGFKLNWMNLRDAETGKILWQGTEDLSVPGVEHEARVPKKILKCKAVSRELNFSSAEQMEKFRLEQKVFFKGQCLEEWFFEFGFVIPNSTNTWQSLIEAAPESQMMPASVLTGNVIIETKFFDDDLLVSTSKVRLFYV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O55057-1", "uniprot_id": "PDE6D_MOUSE", "id": "O55057-1", "name": "Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta", "aln": "MSAKDERARD-ILRGFKLNWMNLRDAETGKILWQGTEDLSVPGVEHEARVPKKILKCKAVSRELNFSSAEQMEKFRLEQKVYFKGQCLEEWFFEFGFVIPNSTNTWQSLIEAAPESQMMPASVLTGNVIIETKFFDDDLLVSTSKVRLFYV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43924-1", "uniprot_id": "PDE6D_HUMAN", "id": "O43924-1", "name": "Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta", "aln": "MSAKDERARE-ILRGFKLNWMNLRDAETGKILWQGTEDLSVPGVEHEARVPKKILKCKAVSRELNFSSTEQMEKFRLEQKVYFKGQCLEEWFFEFGFVIPNSTNTWQSLIEAAPESQMMPASVLTGNVIIETKFFDDDLLVSTSRVRLFYV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VLJ0-1", "uniprot_id": "PDE6D_DROME", "id": "Q9VLJ0-1", "name": "Probable cGMP 3',5'-cyclic phosphodiesterase subunit delta", "aln": "MGSDDQSAGDRIQKGFQINYMILRDADSGKIIWQENKDFSAPDQEHEARVPVKILDMRAVSREINFSTIESMENFRLDQKVLFKGRIMEEWFFEMGFVGANTTNTWQSTIEAAPESQMMPAKVLNGNVTIQTSFYDNETLITKSVVRLYYI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.:.*: * : * :**::*:* ****::***:** .:*:*.*. ******* ***. :*****:***: *.**:***:*** ***: :******:*** .*:****** ************.**.*** *:*.*:*:: *::.* ***:*:", "identical_positions": 93, "similar_positions": 41, "identity": "61.59%" }, { "cls_id": "homologset.agr.MGI:1270844", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZKI3-1", "uniprot_id": "D3ZKI3_RAT", "id": "D3ZKI3-1", "name": "Lipid transferase CIDEB", "aln": "MLDSSLTLPELRSQLYTKTQDFSLHTTEVPSPEAIGGRLAVSHPAMEYLSALSSNGLLRSVSTMSSELSRRVWNSAPPPQRPFRVCDHKRTVRKGLTAATRQELLDKVVETLLLSG--VLTLVLEEDGTAVETEDFFELLEDDTCLMALEQGQSWSP------------------------------------------------------------------------------KSGMLSYG---LGREKPKHSKDIARITFDVYKQNPRDL--------------------------------------------------FGSLNVKATFYGLYSMS-----------CDFQGVGPKKVLR-----------------------ELLRWTSSLLQGLG------------------------------------HMLLGISSTLRHVVEGAERWQWHRQSHLHS--------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70303-1", "uniprot_id": "CIDEB_MOUSE", "id": "O70303-1", "name": "Lipid transferase CIDEB", "aln": "---------------------------------------------MEYLSAFNPNGLLRSVSTVSSELSRRVWNSAPPPQRPFRVCDHKRTVRKGLTAASLQELLDKVLETLLLRG--VLTLVLEEDGTAVDSEDFFQLLEDDTCLMVLEQGQSWSP------------------------------------------------------------------------------KSGMLSYG---LGREKPKHSKDIARITFDVYKQNPRDL--------------------------------------------------FGSLNVKATFYGLYSMS-----------CDFQGVGPKRVLR-----------------------ELLRWTSSLLQGLG------------------------------------HMLLGISSTLRHVVEGADRWQWHGQRHLHS--------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UHD4-1", "uniprot_id": "CIDEB_HUMAN", "id": "Q9UHD4-1", "name": "Lipid transferase CIDEB", "aln": "---------------------------------------------MEYLSALNPSDLLRSVSNISSEFGRRVWTSAPPPQRPFRVCDHKRTIRKGLTAATRQELLAKALETLLLNG--VLTLVLEEDGTAVDSEDFFQLLEDDTCLMVLQSGQSWSPT-----------------------------------------------------------------------------RSGVLSYG---LGRERPKHSKDIARFTFDVYKQNPRDL--------------------------------------------------FGSLNVKATFYGLYSMS-----------CDFQGLGPKKVLR-----------------------ELLRWTSTLLQGLG------------------------------------HMLLGISSTLRHAVEGAEQWQQKGRLHSY---------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F8W414-1", "uniprot_id": "F8W414_DANRE", "id": "F8W414-1", "name": "", "aln": "---------------------------------------------METTSS-----LFKSVS-------RRVWS---PPQRPFRVCSWNREVKKGITAGTLEELKERAGQALLISK--MLTLVCEEDGTEVDSDEFLIALPDNTVFMCLQPEEIWKP-------------------------------------------------------------------------------HPLHQRGGNKPGDSKPRTGKDIAQITFDLYRTHPKDV--------------------------------------------------FGSLNVKATYQGLYSVS-----------ADFQCLGPKKFLR-----------------------EALKMMSTLLHAAG------------------------------------HLLISSAAVIRRIIQGADMLQAQNNKQIKYWE------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A8DY77-1", "uniprot_id": "A8DY77_DROME", "id": "A8DY77-1", "name": "", "aln": "MWSNALCTLGVTKPLCNCLSIRQVAAAAAAAAQATQG----VAASAAAAGGAGVGGGAITTGPSSSVTNGGLSAMESRGKRPLKIWDSWRNVRKGVVVGTFEELLVRGKDKLGVPASEPVRVVLECDGTQIEDGEYFRTLANNTVLLLLRQGERWYPTGVDVIKAAISAIPKIVCETIHALELHDETPSWKIMDNKGRVTVVLHWDQRQGGGSGGGGGGGGAGGGVGSMCSGLGSSNGLLSSDKYSPSKKGLSAQSSLDNKSVSSQSSQPRYASPQITVISDDGPASIYHPGGVVLPPGVVIPGGSRRLSKQGSSFDSTVGVGVGAVHVHTPECAHHAHTPSRAGSPSTTECDFHCCALHEEGRKIAVHKSVATSPIQDGSSSPQPQSAPSVMDPMLGGSGGGGSGSMQRRSSGAKGHVRFLDIAPERDSSESETENTVMEDDKTTTEKFLLLIDQLSVDQKRHLSIKDIGIILERLNSKILDVERLDRESESDDCYNWTIKATIRGDALRELGVIYNGNYYAISEHPGYKEELEENGEEVEEEEEEDEEDRI", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q0E9B7-1", "uniprot_id": "Q0E9B7_DROME", "id": "Q0E9B7-1", "name": "", "aln": "-----------------------MTAMNADETKLAGMPQGAEEEQEPEREQKKESDGAAAAAGVQCDPDSRIVAPPPRQRTLTRTAELDADCED--IELDADDGLDDAADSITLELALSPHSSATPTPSPTTADEDFAQLDNSKPFKIKDITRNIRK-------------------------------------------------------------------------------AVVATTLSELRTKVSLKFERAQPAIHLDCDGTEVDDEE------------------------------------------------YFSTLEPNAELIAVFPGEQWR------DPSDYNANLRRTSLD----------------------AQRLRSLVSKLQPNYMN---------------------------------DDDLDKLSNMDPNSLVDITGREPKDNEYSARSDAARLSTELSC--------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.. : : : . .. :: : : : : : : * :.. : . : .. . ..::. :: . .. .*:: : . . * : . : . . . ", "identical_positions": 3, "similar_positions": 48, "identity": "0.54%" }, { "cls_id": "homologset.agr.MGI:1270845", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AJN5-1", "uniprot_id": "A0A8I6AJN5_RAT", "id": "A0A8I6AJN5-1", "name": "Lipid transferase CIDEA", "aln": "--------METARDYAG-ALIRPLTFMGLQTKKVLLTP---------------------------------LIHPARPFRVSNHDRS---SRRGVMASSLRELISKTLDVL-VITTGLVTLVLEED--------GTVVDTEEFFQTLRDNTHFMILEKGQ--------KWTPGNKYV--CTQTKKSGIARVTFDLYRLNPKD-----------------------------------------FLGCLNVKATMYEMYS--------------VSYDIRCTSFKALLRSLLRFASYAAQ-----VTGQFLVYAGAYVLRALGDTEEQPSPKASAKGWFM-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70302-1", "uniprot_id": "CIDEA_MOUSE", "id": "O70302-1", "name": "Lipid transferase CIDEA", "aln": "--------METARDYAG-ALIRPLTFMGLQTKKVLLTP---------------------------------LIHPARPFRVSNHDRS---SRRGVMASSLQELISKTLDVL-VITTGLVTLVLEED--------GTVVDTEEFFQTLRDNTHFMILEKGQ--------KWTPGSKYVPVCKQPKKSGIARVTFDLYRLNPKD-----------------------------------------FLGCLNVKATMYEMYS--------------VSYDIRCTSFKAVLRNLLRFMSYAAQ-----MTGQFLVYAGTYMLRVLGDTEEQPSPKPSTKGWFM-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60543-1", "uniprot_id": "CIDEA_HUMAN", "id": "O60543-1", "name": "Lipid transferase CIDEA", "aln": "--------MEAARDYAG-ALIRPLTFMGSQTKRVLFTP---------------------------------LMHPARPFRVSNHDRS---SRRGVMASSLQELISKTLDAL-VIATGLVTLVLEED--------GTVVDTEEFFQTLGDNTHFMILEKGQ--------KWMPGSQHVPTCSPPKRSGIARVTFDLYRLNPKD-----------------------------------------FIGCLNVKATMYEMYS--------------VSYDIRCTGLKGLLRSLLRFLSYSAQ-----VTGQFLIYLGTYMLRVLDDKEERPSLRSQAKGRFTCG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B7G0-1", "uniprot_id": "A0ACD6B7G0_DANRE", "id": "A0ACD6B7G0-1", "name": "", "aln": "--------MEYAKTLVPTSLMRSVSSVQTTLAQRMLSP---------------------------------PQP--RPYKVCTPNRR---RRKGFTATSLADLIEQVASSF-LIACQMLTLVLEDD--------GTVVDSEAFFQSLPTNTPFMVLEKGD--------VWTPSKLVLPSFRQPRRSGIAKLSFDLYKLNPKD-----------------------------------------FLGCLTVKATLYEIYT--------------LSYDIKCTRAKYFLMSLLRCFMYMAK-----LTGQVLLCASTYVLRYIGD-EECSS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q0E9B7-1", "uniprot_id": "Q0E9B7_DROME", "id": "Q0E9B7-1", "name": "", "aln": "-----MTAMNADETKLAGMPQGAEEEQEPEREQKKESDGAAAAAG--------------------------VQCDPDSRIVAPPPRQRTLTRTAELDADCEDIELDADDGL-DDAADSITLELALSPHSSATPTPSPTTADEDFAQLDNSKPFKIKDITRNIRKAVVATTLSELRTKVSLKFERAQPAIHLDCDGTEVDDEE-----------------------------------------YFSTLEPNAELIAVFPGEQWRDPSDYNANLRRTSLDAQRLRSLVSKLQPNYMNDDD-----LDKLSNMDPNSLVDITGREPKDNEYSARSDAARLSTELSC--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A8DY77-1", "uniprot_id": "A8DY77_DROME", "id": "A8DY77-1", "name": "", "aln": "MWSNALCTLGVTKPLCNCLSIRQVAAAAAAAAQATQGVAASAAAAGGAGVGGGAITTGPSSSVTNGGLSAMESRGKRPLKIWDSWRN---VRKGVVVGTFEELLVRGKDKLGVPASEPVRVVLECD--------GTQIEDGEYFRTLANNTVLLLLRQGE--------RWYPTGVDVIKAAISAIPKIVCETIHALELHDETPSWKIMDNKGRVTVVLHWDQRQGGGSGGGGGGGGAGGGVGSMCSGLGSSNGLLSSDKYSPSKKGLSAQSSLDNKSVSSQSSQPRYASPQITVISDDGPASIYHPGGVVLPPGVVIPGGSRRLSKQGSSFDSTVGVGVGAVHVHTPECAHHAHTPSRAGSPSTTECDFHCCALHEEGRKIAVHKSVATSPIQDGSSSPQPQSAPSVMDPMLGGSGGGGSGSMQRRSSGAKGHVRFLDIAPERDSSESETENTVMEDDKTTTEKFLLLIDQLSVDQKRHLSIKDIGIILERLNSKILDVERLDRESESDDCYNWTIKATIRGDALRELGVIYNGNYYAISEHPGYKEELEENGEEVEEEEEEDEEDRI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : . : * * . :: . : : : : * . : * * .. : : . . .:. : . * . : .: . : . : . : .. ", "identical_positions": 6, "similar_positions": 38, "identity": "1.06%" }, { "cls_id": "homologset.agr.MGI:1270847", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O60516-1", "uniprot_id": "4EBP3_HUMAN", "id": "O60516-1", "name": "Eukaryotic translation initiation factor 4E-binding protein 3", "aln": "MSTST--------SCPIPG------GRDQLPDCYSTTPGGTLYATTPGGTRIIYDRKFLLECKNSPIARTPPCCLPQIPGVTTPPTAPLSKLEELKEQ-ETEEEIP--DDAQFEMDI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q80VV3-1", "uniprot_id": "4EBP3_MOUSE", "id": "Q80VV3-1", "name": "Eukaryotic translation initiation factor 4E-binding protein 3", "aln": "MSSST--------SCPIPG------CRDQLPDGYSTTPGGTLYATTPGGTRIIYDRKFLLECKNSPIARTPPCCLPQIPGVTTLPAVPPSKLELLKEQKQTEVEIT--DDEQFEMDM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q98TT6-1", "uniprot_id": "4EB3L_DANRE", "id": "Q98TT6-1", "name": "Eukaryotic translation initiation factor 4E-binding protein 3-like", "aln": "MSTNTQQ----SKSCPIPTRVLHLKDWSQLPDCYSQTPGGTLFSTTPGGTRIIYDRKFLLDCRNSPIARTPPCCLPQIPGVTIPSLHPVSKLQELKEELEEEKELAA-DDSQFEMDI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9XZ56-1", "uniprot_id": "4EBP_DROME", "id": "Q9XZ56-1", "name": "Eukaryotic translation initiation factor 4E-binding protein", "aln": "MSASPTARQAITQALPMITRKVVISDPIQMPEVYSSTPGGTLYSTTPGGTKLIYERAFMKNLRGSPLSQTPPSNVPSCLLRGTPRTPFRKCVPVPTELIKQTKSLKIEDQEQFQLDL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:.. : *: *:*: ** ******::******::**:* *: : :.**:::***. :*. . : .* : .: *: **::*:", "identical_positions": 34, "similar_positions": 32, "identity": "29.06%" }, { "cls_id": "homologset.agr.MGI:1270848", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JKF8-1", "uniprot_id": "RASD1_RAT", "id": "Q9JKF8-1", "name": "Dexamethasone-induced Ras-related protein 1", "aln": "---------------------------------------------------------------------------------------------------------------------------MKLAAMIKKMCPSD------------------SELSIP-AKNCYRMVILGSSKVGKTAIVSRFLTGRFEDAYTPTIEDFHRKFYSIRGEVYQLDILDTSGNHPFPAMRRLSILTGDVFILVFSLDNRDSFEEVQRLKQQILDTKSCLKN-----KTKENVDVPLVICGNKGDRDFYREVEQREIEQLVGDDPQRCAYFEISAKKNSSLDQMFRALFAMAKLPSEMSPDLHR-KVSVQYCDVLHKKALRNKKLLRAGSGGGG-DHGDAFGILAPFARRPSVHSDLMYIREKTSVSSQAKDK------ERCVIS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35626-1", "uniprot_id": "RASD1_MOUSE", "id": "O35626-1", "name": "Dexamethasone-induced Ras-related protein 1", "aln": "---------------------------------------------------------------------------------------------------------------------------MKLAAMIKKMCPSD------------------SELSIP-AKNCYRMVILGSSKVGKTAIVSRFLTGRFEDAYTPTIEDFHRKFYSIRGEVYQLDILDTSGNHPFPAMRRLSILTGDVFILVFSLDNRDSFEEVQRLKQQILDTKSCLKN-----KTKENVDVPLVICGNKGDRDFYREVEQREIEQLVGDDPQRCAYFEISAKKNSSLDQMFRALFAMAKLPSEMSPDLHR-KVSVQYCDVLHKKALRNKKLLRAGSGGGG-DHGDAFGILAPFARRPSVHSDLMYIREKTSVGSQAKDK------ERCVIS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y272-1", "uniprot_id": "RASD1_HUMAN", "id": "Q9Y272-1", "name": "Dexamethasone-induced Ras-related protein 1", "aln": "---------------------------------------------------------------------------------------------------------------------------MKLAAMIKKMCPSD------------------SELSIP-AKNCYRMVILGSSKVGKTAIVSRFLTGRFEDAYTPTIEDFHRKFYSIRGEVYQLDILDTSGNHPFPAMRRLSILTGDVFILVFSLDNRDSFEEVQRLRQQILDTKSCLKN-----KTKENVDVPLVICGNKGDRDFYREVDQREIEQLVGDDPQRCAYFEISAKKNSSLDQMFRALFAMAKLPSEMSPDLHR-KVSVQYCDVLHKKALRNKKLLRAGSGGGGGDPGDAFGIVAPFARRPSVHSDLMYIREKASAGSQAKDK------ERCVIS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VS10-1", "uniprot_id": "Q9VS10_DROME", "id": "Q9VS10-1", "name": "GTP-binding protein Rhes", "aln": "MYRCKNWFCARSNNNNYVDVALSEAPPIHPSAATTTTPNSRNFSASNNNNVRSNSSKSNQQTAAHRGATTHPTQIPHTHHPSTTHSTDEASPPQAHVVTFLDESTAGGSNGAVTSSRLVTTAELHQAHMLEHHSNLDAIEQADDFIYGPGAGLSLCDDSLPSAKNCYRLVMLGSSRAGKSSIVARFLGNRFEEAYTPTIEEFHRKLYRIRNEVFQLDILDTSGYHPFPAMRRLSFLTGDLFILVFSMDSRESFEEVVRLRENILETKWAALNPGSGFKKKSLPKIPMILAGNKCDRDF-KTVQVDEVMGYIAGQDNCCTFVECSARQNYRIDDLFHSLFTVSNLPLEMTPNHHRRLVSVFGAPSPLPPHGSAVGGTKKNALSIKRRFSDACGVVTPNARRPSIRTDLNLMRSKTMALNEGEGVRSPSRWNRCALM", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: * *::: . * .: *:* ******:*:****:.**::**:*** .***:*******:****:* **.**:********* **********:****:******:*.*:***** **:::**:** . * *.*. .:*:::.*** **** : *: *: :..: : *::.* **::* :*::*::**::::** **:*: ** *** . : .: . .** *:::* *****:::** :*.*: . .:.:. :**.: ", "identical_positions": 131, "similar_positions": 88, "identity": "30.11%" }, { "cls_id": "homologset.agr.MGI:1270849", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P23443-1", "uniprot_id": "KS6B1_HUMAN", "id": "P23443-1", "name": "Ribosomal protein S6 kinase beta-1", "aln": "-------------------------MRRRRRRDGFYPAPDFRDREAEDMAGVFDIDLDQPEDAGSEDELEEGGQLNESMDHGGVGPYELGMEHCEKFEISETSVNRGPEKIRPE------------CFELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHTK-------------------------AERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCKESIHDGTVT----------HTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLN--LPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEELLARKVEPPFKPLLQSEEDVSQFDSKFTRQTPVDSPDDSTLSESANQVFLGFTYVAPSVLESVKEKFSFEPKIRSPRRFIGSPRTPVSPVKFSPGDFWGRG----ASASTANPQTPVEYPMETSGIEQMDVTMSGEASAPLPIRQP---NSGPYKKQAFPMISKRPEHLRMNL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P67999-1", "uniprot_id": "KS6B1_RAT", "id": "P67999-1", "name": "Ribosomal protein S6 kinase beta-1", "aln": "-------------------------MRRRRRRDGFYPAPDFRHREAEDMAGVFDIDLDQPEDAGSEDELEEGGQLNESMDHGGVGPYELGMEHCEKFEISETSVNRGPEKIRPE------------CFELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHTK-------------------------AERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCKESIHDGTVT----------HTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLN--LPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEELLARKVEPPFKPLLQSEEDVSQFDSKFTRQTPVDSPDDSTLSESANQVFLGFTYVAPSVLESVKEKFSFEPKIRSPRRFIGSPRTPVSPVKFSPGDFWGRG----ASASTANPQTPVEYPMETSGIEQMDVTTSGEASAPLPIRQP---NSGPYKKQAFPMISKRPEHLRMNL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BSK8-1", "uniprot_id": "KS6B1_MOUSE", "id": "Q8BSK8-1", "name": "Ribosomal protein S6 kinase beta-1", "aln": "-------------------------MRRRRRRDGFYLAPDFRHREAEDMAGVFDIDLDQPEDAGSEDELEEGGQLNESMDHGGVGPYELGMEHCEKFEISETSVNRGPEKIRPE------------CFELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHTK-------------------------AERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCKESIHDGTVT----------HTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLN--LPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEELLARKVEPPFKPLLQSEEDVSQFDSKFTRQTPVDSPDDSTLSESANQVFLGFTYVAPSVLESVKEKFSFEPKIRSPRRFIGSPRTPVSPVKFSPGDFWGRG----ASASTANPQTPVEYPMETSGIEQMDVTVSGEASAPLPIRQP---NSGPYKKQAFPMISKRPEHLRMNL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8N7UVV0-1", "uniprot_id": "A0A8N7UVV0_DANRE", "id": "A0A8N7UVV0-1", "name": "Ribosomal protein S6 kinase", "aln": "------------------------------------------------MAGVFDIDLDPPEDNVSDEELSDGAKINEYIDQCSG--FEF-MEDCEKFEISEDSVNQGTEKIRPE------------CFELLRVLGKGGYGKVFQVRKVAGAASGKIFAMKVLKKAMIVRNAKDTAHTK-------------------------AERSILEEVKHPFIVDLIYAFQTGEKLYLILEYLSGGELFMQLEREGIFLEDTACFYLAEISLALGHLHQKGIIYRDLKPENIMLNYNGHVKLTDFGLCKESIHDGTVT----------HTFCGTIEYMAPEILTRSGHNRAVDWWSLGALMYDMLTGAPPFTAENRKKTIDKILKCKLN--LPPYLTQEARDLLKKLLKRNASVRIGASPRDVLDIQRHSFFRHINWDDLLAFKIDPPFKPFLQSADDVSQFDSKFTSQTPVDSPDDTKLSESDNQVFLGFTYIAPSVLENIKEKFTFEPKSRSPRKVLGSPRTPVSPLKAEVEDGWSRGPLFPEVTTSSSLLPPTGALKQASNVEQMDMSSNMEASAPLPIKKPLGSNTGSFMKQPHPVGGRRPKHLKMKL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q94533-1", "uniprot_id": "Q94533_DROME", "id": "Q94533-1", "name": "Ribosomal protein S6 kinase", "aln": "-------------------------------------MADVSDPSELFDLELHDLELQDDKARDSDDDRIELDDVDLEPELCIN--LHQDTEGQETIQLCEENVNPGKIKLGPK------------DFELKKVLGKGGYGKVFQVRKTAGRDANKYFAMKVLKKASIVTNQKDTAHTR-------------------------AERNILEAVKHPFIVELVYAFQTDGKLYLILEYLSGGELFMHLEREGIFLEDTTCFYLSEIILALGHLHKLGIIYRDLKPENILLDAQGHVKLTDFGLCKEHIQEGIVT----------HTFCGTIEYMAPEILTRSGHGKAVDWWSLGALMFDMLTGVPPFTAENRKKTIETILKAKLN--LPAYLTPEARDLVRRLMKRQEPQRLGSGPEDAAAVQIHPFFKHVNWDDVLARRLEPPIKPLLRSEDDVSQFDTRFTRQIPVDSPDDTTLSESANLIFQGFTYVAPSILEDMHRANRMP--ARSPRRTPRQLPDSSFRLQFPS-----------ANVGANAPLAMHGHSQRSGMFARATPPHHMQTFAPRPSPAQ----DEMMDVQGLPMV-----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38070-1", "uniprot_id": "YPK3_YEAST", "id": "P38070-1", "name": "Serine/threonine-protein kinase YPK3", "aln": "MIFSLDEELHRVSLDDKKNDIKVDYSSAIYNDINHEQGSSITYEESINHLSVHSNAIPLNGMSPAHRMRRRSSAYSKFPILTPPNTRRFSITGSDAMRTNTNRLSITPQDIISSNIGENELSRNLHDFKPVRVLGQGAYGKVLLVKDVN---TSKLYAMKQLRKAEILISQTATDSKREDEDKNDGNNNDNDDGLSKRLERTFAERSILSEIEHPNIVKLFYSFHDNSKLYLLLQYIPGGELFYHLKEHGTLDETTVSFYAAEISCALRFLHTKGVVYRDLKPENCLLNQRGHLVLTDFGLSKKSANDSAVDEEDPENVNALYSIIGTPEYCAPEILLGKAYSQNCDWYSLGCLLYDMLVGKPPYTGSNHKVIINKIQQNKQGPKIPFYLSEGMKDILNALLKKETAKRWN--------------------VDKYWAKTGANNKPTKSKKKKSGAARTSLFTEHFIFRKIDWKLLESGQLQKTTLGPIVP-VITDLELAENFD--------------------------------------TEFTSMSYEETYTDSKPININSVSKSPDMFKGFSYKAS-----GSYLEKYF--------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.. : :. . . : :. :. .: .. *: :***:*.****: *:.. :.* :*** *:** *: . . * .: ***.**. ::** **.*.*:*: . ****:*:*:.***** :*:..* : * *..** :** ** .** *::******** :*: .**: ******.*: ::. * ::: ** ** ***** ..:.: **:***.*::***.* **:*..*:* *:.* : * . :* **: :*::. *:*:: . * . : : . ** . .. . : : : : * .* ** : : :.* :: .:. : . : . . : . : ", "identical_positions": 115, "similar_positions": 128, "identity": "18.98%" }, { "cls_id": "homologset.agr.MGI:1270850", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LQW0-1", "uniprot_id": "F1LQW0_RAT", "id": "F1LQW0-1", "name": "Transporter", "aln": "MLLARMKPQVQPELGGADQLPEQPLRP-CKTADLLVVKEHNGVQCL------------LASQDGDAQPRETWGKKIDFLLSVVGFAVDLANVWRFPYLCYKNGGGAFLIPYTLFLIIAGMPLFYMELALGQFNREGAATVW-KICPFFKGVGYAVILIALYVGFYYNVIIAWSLYYLFASFTLNLPWTNCGHAWNSPNCTDPKLLNAS---VLGDHTKYSKYKF---------------------------TPAAEFYERGVLHLHESSGIHDIGLPQWQLLLCLMVVIVVLYFSLWKGVKTSGKVVWITATLPYFVLFVLLVHGVTLPGASNGINAYLHIDFYRLKEATVWIDAATQIFFSLGAGFGVLIAFASYNKFDNNCYRDALLTSTINCVTSFISGFAIFSILGYMAHEHKVKIEDVATEGAGLVFVLYPEAISTLSGSTFWAVLFFLMLLALGLDSSMGGMEAVITGLADDFQVLKRHRKLFTCAVTLGTFLLAMFCITKGGIYVLTLLDTFAAGTSILFAVLMEAIGVSWFYGVDRFSNDIQQMMGFKPGLYWRLCWKFVSPAFLLFVVVVSIINFKPLTYDDYVYPPWANWVGWGIALSSMILVPAYVIYKFFSIRGSLWERVAYGITPENEHHLVAQR------DVRQFQLRHWLAI------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O55192-1", "uniprot_id": "SC6A2_MOUSE", "id": "O55192-1", "name": "Sodium-dependent noradrenaline transporter", "aln": "MLLARMNPQVQPELGGADPLPEQPLRP-CKTADLLVVKERNGVQCL------------LASQDSDAQPRETWGKKIDFLLSVVGFAVDLANVWRFPYLCYKNGGGAFLIPYTLFLIIAGMPLFYMELALGQYNREGAATVW-KICPFFKGVGYAVILIALYVGFYYNVIIAWSLYYLFASFTLNLPWTNCGHSWNSPNCTDPKLLNAS---VLGDHTKYSKYKF---------------------------TPAAEFYERGVLHLHESSGIHDIGLPQWQLLLCLMVVIVVLYFSLWKGVKTSGKVVWITATLPYFVLFVLLVHGVTLPGASNGINAYLHIDFYRLKEATVWIDAATQIFFSLGAGFGVLIAFASYNKFDNNCYRDALLTSTINCVTSFISGFAIFSILGYMAHEHKVNIEDVATEGAGLVFILYPEAISTLSGSTFWAVLFFLMLLALGLDSSMGGMEAVITGLADDFQVLKRHRKLFTCVVTISTFLLALFCITKGGIYVLTLLDTFAAGTSILFAVLMEAIGVSWFYGVDRFSNDIQQMMGFKPGLYWRLCWKFVSPAFLLFVVVVSIINFKPLTYDDYTYPPWANWVGWGIALSSMILVPAYVIYKFLSIRGSLWERVAYGITPENEHHLVAQR------DVRQFQLRHWLAI------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P23975-1", "uniprot_id": "SC6A2_HUMAN", "id": "P23975-1", "name": "Sodium-dependent noradrenaline transporter", "aln": "MLLARMNPQVQPENNGADTGPEQPLRA-RKTAELLVVKERNGVQCL------------LAPRDGDAQPRETWGKKIDFLLSVVGFAVDLANVWRFPYLCYKNGGGAFLIPYTLFLIIAGMPLFYMELALGQYNREGAATVW-KICPFFKGVGYAVILIALYVGFYYNVIIAWSLYYLFSSFTLNLPWTDCGHTWNSPNCTDPKLLNGS---VLGNHTKYSKYKF---------------------------TPAAEFYERGVLHLHESSGIHDIGLPQWQLLLCLMVVVIVLYFSLWKGVKTSGKVVWITATLPYFVLFVLLVHGVTLPGASNGINAYLHIDFYRLKEATVWIDAATQIFFSLGAGFGVLIAFASYNKFDNNCYRDALLTSSINCITSFVSGFAIFSILGYMAHEHKVNIEDVATEGAGLVFILYPEAISTLSGSTFWAVVFFVMLLALGLDSSMGGMEAVITGLADDFQVLKRHRKLFTFGVTFSTFLLALFCITKGGIYVLTLLDTFAAGTSILFAVLMEAIGVSWFYGVDRFSNDIQQMMGFRPGLYWRLCWKFVSPAFLLFVVVVSIINFKPLTYDDYIFPPWANWVGWGIALSSMVLVPIYVIYKFLSTQGSLWERLAYGITPENEHHLVAQR------DIRQFQLQHWLAI------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1R3H6-1", "uniprot_id": "F1R3H6_DANRE", "id": "F1R3H6-1", "name": "Transporter", "aln": "-----MNIQVLPEHKLSSVAPLKQFNVEKKEVELILVKEQNGVQYTNSSVVASPSSRACTSASGEEIERETWGKKMDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLIPYVLFLFIAGMPLFYMELALGQYNREGAATLW-KICPVFKGVGYTVIVIALYVGFYYNVIIAWSLYYLYASLTSELPWLHCNNPWNSPNCTEPKDINGT---VLGNGTSYAKYKN---------------------------TPAAEFYERGVLHSHESKGIGDLGLPRWELTICLVVVAFILYFSLWKGVKSSGKVVYITATMPYIVLLVLLIRGITLPGAMNGIRAYLHIDLKKLNNPQVWIDAATQIFFSLGAGFGVLIAFSSYNKFNNNCYRDAILTSTINCVTSFFSGFAIFSVLGYMAEQHKVNIKDVATEGAGLVFVIYPEAISTLPGATFFAIVFFIMLLTLGIDSSMGGMEAVLTGLSDDFKILKRNRKLFTFATVVGTFLMALLCVTNGGIYVLTLLDKYAAGTSILFGVLFEAIGVSWFYGVDRFSEDIERMMGFKPGIYWRLCWKFVSPAFLLLVVIASIVTSGRLTYDEYVFPYWADMLGWSIALSSMLFVPFYAIYKFFSVPSSFKERLAYCVTPEHEHHLVAEG------NVRQFKLKHWLTI------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7K4Y6-1", "uniprot_id": "DAT_DROME", "id": "Q7K4Y6-1", "name": "Sodium-dependent dopamine transporter", "aln": "---------MSPTGHISKSKTPTPHDN-----------DNNSISDE----------------------RETWSGKVDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYGIMLVVGGIPLFYMELALGQHNRKGAITCWGRLVPLFKGIGYAVVLIAFYVDFYYNVIIAWSLRFFFASFTNSLPWTSCNNIWNTPNCRPFESQNASRVPVIGNYSDLYAMGNQSLLYNETYMNGSSLDTSAVGHVEGFQSAASEYFNRYILELNRSEGIHDLGAIKWDMALCLLIVYLICYFSLWKGISTSGKVVWFTALFPYAVLLILLIRGLTLPGSFLGIQYYLTPNFSAIYKAEVWVDAATQVFFSLGPGFGVLLAYASYNKYHNNVYKDALLTSFINSATSFIAGFVIFSVLGYMAHTLGVRIEDVATEGPGLVFVVYPAAIATMPASTFWALIFFMMLLTLGLDSSFGGSEAIITALSDEFPKIKRNRELFVAGLFSLYFVVGLASCTQGGFYFFHLLDRYAAGYSILVAVFFEAIAVSWIYGTNRFSEDIRDMIGFPPGRYWQVCWRFVAPIFLLFITVYGLIGYEPLTYADYVYPSWANALGWCIAGSSVVMIPAVAIFKLLSTPGSLRQRFTILTTPWRDQQSMAMVLNGVTTEVTVVRLTDTETAKEPVDV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * :. . :.*.:. ****. *:******:*************************:** ::*.:.*:***********.**:** * * :: *.***:**:*::**:**.*********** ::::*:* .*** *.: **:*** : *.: *:*: :. :.*:*:::* :*. :.*.** *:* :*:: :**::* .: *******:.:*****::** :** **::**::*:****: **. ** :: : :. **:*****:*****.*****:*::****:.** *:**:*** **. ***.:**.***:*****. *.*:******.****::** **:*:..:**:*::**:***:**:***:** **::*.*:*:* :**:*:**. *::.: . *:**:*.: *** :*** ***..*::***.***:**.:***:**. *:** ** **::**:**:* ***::.: .:: *** :* :* **: :** ** **::::* .*:*::* .*: :*.: ** .::: :* :: .:* . : ", "identical_positions": 291, "similar_positions": 186, "identity": "43.24%" }, { "cls_id": "homologset.agr.MGI:1270851", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O09051-1", "uniprot_id": "GUC2B_MOUSE", "id": "O09051-1", "name": "Guanylate cyclase activator 2B", "aln": "-----MSRSQLWAAVVLLLLLQSAQGVYIKYHGFQVQLESVKKLNELEEKEMSNPQPRRSGLLPAVCHNPALPLDLQPVCASQEAASTFKALRTIATDECELCINVACTGC-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P70668-1", "uniprot_id": "GUC2B_RAT", "id": "P70668-1", "name": "Guanylate cyclase activator 2B", "aln": "-----MSGSQLWAAVLLLLVLQSAQGVYIKYHGFQVQLESVKKLNELEEKQMSDPQQQKSGLLPDVCYNPALPLDLQPVCASQEAASTFKALRTIATDECELCINVACTGC-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q16661-1", "uniprot_id": "GUC2B_HUMAN", "id": "Q16661-1", "name": "Guanylate cyclase activator 2B", "aln": "MGCRAASGLLPGVAVVLLLLLQSTQSVYIQYQGFRVQLESMKKLSDLEAQWAPSPRLQAQSLLPAVCHHPALPQDLQPVCASQEASSIFKTLRTIANDDCELCVNVACTGCL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .**:***:***:*.***:*:**:*****:***.:** : ..*: : ..*** **::**** ***********:* **:*****.*:****:******* ", "identical_positions": 67, "similar_positions": 25, "identity": "59.82%" }, { "cls_id": "homologset.agr.MGI:1270854", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9NFT7-1", "uniprot_id": "HXK2_DROME", "id": "Q9NFT7-1", "name": "Hexokinase-2", "aln": "--------MR----KSTRLLTHS-------------LFGPVFKILFHNKTVCGGCNRKMPSLVNTEIEAAVKG----------------------------FLIDQEKMTEVVERMTKEIKMGLAKDTHARAV-----IKCFVSHVQDLPTGKERGKYLALDLGGSNFRVLLVNLISNSD----VETMSKGYNFPQTLMSGS---GKALFDFLAECLSEFCHSHGLE--------NESLALGFTFSFPLQQQGLSKGILVAWTKGFSCEGVVGKNVVSLLQEAIDRRGDLKINTVAILNDTVGTLMSCAFYHP-----------NCRIGLIVGTGSNACYVEKTVNAECFEGYQTS-----PKPSMIINCEWGAFGDNGVLEFVRTSYDKAVDKV-TPNPGKQTFEKCISGMYMGELVRLVITDMIAKGFMFH-----GIISEKIQERWSFKTAYISDVESDAPGEYRNCNKVLSELGILGCQEPDKEALRYICEAVSSRSAKLCACGLVTIINKMNIN------EVAIGIDGSVYRFHPKYHDMLQYHMKKLLK------PGVKFELVVSEDGSGRGAALVAATAVQAKSKL---------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W330-1", "uniprot_id": "Q9W330_DROME", "id": "Q9W330-1", "name": "Phosphotransferase", "aln": "MDRELNGAMKSVSINSAQLNGHNNGGGLDETDRVGVAQGAALSATEKITTTTAAATKSATATTNATTATATTTNLTTHSPQQIALLSAAEKSKMVHELCQQLLLTDEQVQELCYRILHELRRGLAKDTHPKAN-----VKCFVTYVQDLPNGNERGKFLALDLGGTNFRVLLIHLQENND----FQMESRIYAIPQHIMIGS---GTQLFDHIAECLSNFMAEHNVY--------KERLPLGFTFSFPLRQLGLTKGLLETWTKGFNCAGVVNEDVVQLLKDAIARRGDVQIDVCAILNDTTGTLMSCAWKNH-----------NCKIGLIVGTGANACYMERVEEAELFAAEDPR-----KK-HVLINTEWGAFGDNGALDFVRTEFDRDIDVH-SINPGKQTFEKMISGMYMGELVRLVLVKMTQAGILFN-----GQDSEVLNTRGLFFTKYVSEIEADEPGNFTNCRLVLEELGLTNATDGDCANVRYICECVSKRAAHLVSAGIATLINKMDEP------TVTVGVDGSVYRFHPKFHNLMVEKISQLIK------PGITFDLMLSEDGSGRGAALVAAVACREDILNGKK------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P52792-1", "uniprot_id": "HXK4_MOUSE", "id": "P52792-1", "name": "Hexokinase-4", "aln": "--------------------------------------------MLDDRARMEATKKEKVEQILAE-----------------------------------FQLQEEDLKKVMSRMQKEMDRGLKLETHQEAS-----VKMLPTYVRSTPEGSEVGDFLSLDLGGTNFRVMLVKVGEGEAGQWSVKTKHQMYSIPEDAMTGT---AEMLFDYISECISDFLDKHQMK--------HKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNIVGLLRDAIKRRGDFEMDVVAMVNDTVATMISCYYEDR-----------QCEVGMIVGTGCNACYMEEMQNVELVEGDE---------GRMCVNTEWGAFGNSGELDEFLLEYDRMVDES-SVNPGQQLYEKIIGGKYMGELVRLVLLKLVEENLLFH-----GEASEQLRTRGAFETRFVSQVESD-SGDRRQILNILSTLGLR-PSVADCDIVRRACESVSTRAAHMCSAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSFKERFHASVRRLT-------PNCEITFIESEEGSGRGAALVSAVACKKACMLGQ-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P17712-1", "uniprot_id": "HXK4_RAT", "id": "P17712-1", "name": "Hexokinase-4", "aln": "--------------------------------------------MLDDRARMEATKKEKVEQILAE-----------------------------------FQLQEEDLKKVMSRMQKEMDRGLRLETHEEAS-----VKMLPTYVRSTPEGSEVGDFLSLDLGGTNFRVMLVKVGEGEAGQWSVKTKHQMYSIPEDAMTGT---AEMLFDYISECISDFLDKHQMK--------HKKLPLGFTFSFPVRHEDLDKGILLNWTKGFKASGAEGNNIVGLLRDAIKRRGDFEMDVVAMVNDTVATMISCYYEDR-----------QCEVGMIVGTGCNACYMEEMQNVELVEGDE---------GRMCVNTEWGAFGDSGELDEFLLEYDRMVDES-SANPGQQLYEKIIGGKYMGELVRLVLLKLVDENLLFH-----GEASEQLRTRGAFETRFVSQVESD-SGDRKQIHNILSTLGLR-PSVTDCDIVRRACESVSTRAAHMCSAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSFKERFHASVRRLT-------PNCEITFIESEEGSGRGAALVSAVACKKACMLAQ-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P35557-1", "uniprot_id": "HXK4_HUMAN", "id": "P35557-1", "name": "Hexokinase-4", "aln": "--------------------------------------------MLDDRARMEAAKKEKVEQILAE-----------------------------------FQLQEEDLKKVMRRMQKEMDRGLRLETHEEAS-----VKMLPTYVRSTPEGSEVGDFLSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGT---AEMLFDYISECISDFLDKHQMK--------HKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNVVGLLRDAIKRRGDFEMDVVAMVNDTVATMISCYYEDH-----------QCEVGMIVGTGCNACYMEEMQNVELVEGDE---------GRMCVNTEWGAFGDSGELDEFLLEYDRLVDES-SANPGQQLYEKLIGGKYMGELVRLVLLRLVDENLLFH-----GEASEQLRTRGAFETRFVSQVESD-TGDRKQIYNILSTLGLR-PSTTDCDIVRRACESVSTRAAHMCSAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSFKERFHASVRRLT-------PSCEITFIESEEGSGRGAALVSAVACKKACMLGQ-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9NFT9-1", "uniprot_id": "HXK1_DROME", "id": "Q9NFT9-1", "name": "Hexokinase-like protein", "aln": "--------------------------------------------MANTFNPEEDFPEVYKVCKLFN-------------------------------------PSIDDLEKIKNAMDREITMGLSRDHHDRST-----VPCHLSYVQDLPTGRERGQFLALEMMPTNCRIMLVKFSSERD----IYTSSKCVIMPHTVAAGR---GTEVFTFLATSIANFVKEKKVD--------KDNLPLGIAFAFTLKKLALDVGILVSWTKEFGAQGAIGKDVVQLLRDALAKFPEISVDVMGIINVGAGSLLALCWAQP-----------DTRIGLIMGSIANSCYVERVERCETYEGDE-------YRKLMIINSDWAHFGDTGQLDFIRNEYDRQLDTE-SINPGTRIYEKFSGALCMGELVRIIVLRLMKSGAIFA-----EDRRDYIGIQWKLDMVSLIEIVSDPPGVYTKAQEVMDKFRIRHCKERDLAALKYICDTVTNRAAMLVASGVSCLIDRMRLP------QISIAVDGGIYRLHPTFSTVLNKYTRLLAD------PNYNFEFVITQDSCGVGAAIMAGMAHANKYKTDAKLFTMDY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P04806-1", "uniprot_id": "HXKA_YEAST", "id": "P04806-1", "name": "Hexokinase-1", "aln": "-----------------------------------MVHLGPKKPQARKGSMADVPKELMDEIHQLED---------------------------------MFTVDSETLRKVVKHFIDELNKGLT--KKGGN------IPMIPGWVMEFPTGKESGNYLAIDLGGTNLRVVLVKLSGNHT----FDTTQSKYKLPHDMRTTK--HQEELWSFIADSLKDFMVEQELLNTKD------TLPLGFTFSYPASQNKINEGILQRWTKGFDIPNVEGHDVVPLLQNEISKRELP-IEIVALINDTVGTLIASYYTDP-----------ETKMGVIFGTGVNGAFYDVVSDIEKLEGKLADDIPS--NSPMAINCEYGSFDN-EHLVLPRTKYDVAVDEQ-SPRPGQQAFEKMTSGYYLGELLRLVLLELNEKGLMLK-----DQDLSKLKQPYIMDTSYPARIEDDPFENLEDTDDIFQKDFGVKTTLPERKLIRRLCELIGTRAARLAVCGIAAICQK------RGYKTGHIAADGSVYNKYPGFKEAAAKGLRDIYGWTGDASKD-PITIVPAEDGSGAGAAVIAALSEKRIAEGKSLGIIGA-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P04807-1", "uniprot_id": "HXKB_YEAST", "id": "P04807-1", "name": "Hexokinase-2", "aln": "-----------------------------------MVHLGPKKPQARKGSMADVPKELMQQIENFEK---------------------------------IFTVPTETLQAVTKHFISELEKGLS--KKGGN------IPMIPGWVMDFPTGKESGDFLAIDLGGTNLRVVLVKLGGDRT----FDTTQSKYRLPDAMRTTQ--NPDELWEFIADSLKAFIDEQFPQGISE------PIPLGFTFSFPASQNKINEGILQRWTKGFDIPNIENHDVVPMLQKQITKRNIP-IEVVALINDTTGTLVASYYTDP-----------ETKMGVIFGTGVNGAYYDVCSDIEKLQGKLSDDIPP--SAPMAINCEYGSFDN-EHVVLPRTKYDITIDEE-SPRPGQQTFEKMSSGYYLGEILRLALMDMYKQGFIFK-----NQDLSKFDKPFVMDTSYPARIEEDPFENLEDTDDLFQNEFGINTTVQERKLIRRLSELIGARAARLSVCGIAAICQK------RGYKTGHIAADGSVYNRYPGFKEKAANALKDIYGWTQTSLDDYPIKIVPAEDGSGAGAAVIAALAQKRIAEGKSVGIIGA-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P17709-1", "uniprot_id": "HXKG_YEAST", "id": "P17709-1", "name": "Glucokinase-1", "aln": "-----------------------------------MSFDDLHKATER---------AVIQAVDQICD---------------------------------DFEVTPEKLDELTAYFIEQMEKGLAPPKEGHTLASDKGLPMIPAFVTGSPNGTERGVLLAADLGGTNFRICSVNLHGDHT----FSMEQMKSKIPDDLLDDENVTSDDLFGFLARRTLAFMKKYHPDELAK-GKDAKPMKLGFTFSYPVDQTSLNSGTLIRWTKGFRIADTVGKDVVQLYQEQLSAQGMPMIKVVALTNDTVGTYLSHCYTSDNTDSMTSGEISEPVIGCIFGTGTNGCYMEEINKITKLPQELRDKLIKEGKTHMIINVEWGSFDN-ELKHLPTTKYDVVIDQKLSTNPGFHLFEKRVSGMFLGEVLRNILVDLHSQGLLLQQYRSKEQLPRHLTTPFQLSSEVLSHIEIDDSTGLRETELSLLQSLRLPTTPTERVQIQKLVRAISRRSAYLAAVPLAAILIKTNALNKRYHGEVEIGCDGSVVEYYPGFRSMLRHALALSP---LGAEGERKVHLKIAKDGSGVGAALCALVA----------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q04409-1", "uniprot_id": "EMI2_YEAST", "id": "Q04409-1", "name": "Putative glucokinase-2", "aln": "-----------------------------------MSFENLHKVNAE---------ALEDAVVEICS---------------------------------SLQVDAAKLDELTAYFIECMEKGLNNTSVGEEKTVDKGLPMIPTYVTSLPNGTERGVLLAADLGGTHFRVCSVTLNGDGT----FDMQQLKSKIPEEYLNDKDVTSEELFSYLGRRTRAFVRKHHPELLKSTGENIKPLKMGFTFSYPVDQTSLSSGTLIRWTKSFKIEDTVGKDVVRLYQEQLDIQGLSMINVVALTNDTVGTFLSHCYTSG-SRPSSAGEISEPVIGCIFGTGTNGCYMEDIENIKKLPDELRTRLLHEGKTQMCINIEWGSFDN-ELKHLSATKYDIDIDQKFSPNPGYHLFEKRISGMYLGELLRNILVDLHARGLILGQYRNYDQLPHRLKTPFQLCSEVLSRIEIDDSTNLRETELSFLQSLRLPTTFEERKAIQNLVRSITRRSAYLAAVPIAAILIKTNALNKRYHGEVEIGFDGYVIEYYPGFRSMLRHALALSP---IGTEGERKIHLRLAKDGSGVGAALCALVA----------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : : ** : * * * * * *: :: :: *: : . . :*. :: .:. * . : :*::*::. : : * * *** * . ..::* : :. : :. .: * ..: :: : : :* *.*: *..: : : :* ::. *.: .:* :* : .** : :** .. :**::* : : . :: : : : * . : : :: : *:* : : : : :. ** : . :* : . : :::..* ***: : : ", "identical_positions": 46, "similar_positions": 112, "identity": "7.64%" }, { "cls_id": "homologset.agr.MGI:1270855", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AF93-1", "uniprot_id": "A0A8I6AF93_RAT", "id": "A0A8I6AF93-1", "name": "Pro-interleukin-16", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGLAPWGQKCICKGQVQQLGCGCPVLPAGGGHHQYALWHIHRRTPLLGCQGTAPPPCCSWHLLPGQANRTHAAAAKPSSSTTHRPRPGEQERKKRGLTS---SLRMEPHSHSGKSRKSTKFRSISRS--LILCNAKTSDDSS-------------------------------SPDEKYP-DPFETSLCQD-------------KEGFFHSSMQLADTSEAGLSNIPDLALASEAAQLQAAGSDRGKHCRKMFFLKESS---------TTSSKEKAGKSEAQ----SSNFLFP--------------------KACHQRTRSNSTSVNPYSAREMDFPMTKKSAAP--TDRQPYSLCSNRKSLSQQLDYP---VSGTARPTRSLSTAQLGQLSGGLQASVISN-------------------------------------------IVLMKGQAKGLG----------------FSIVGGKDSIYGPIGIYVK-----------------SIFAGGAAAADGRLQEGDEILELNGESIAG-------------------------------------------------------------------------------------------------------------------LTHQDALQKFKQAKKG-------------------------------------------LLTLTVRTRLTTPPSLCSH---------------------------------------------------------------------------LSPPLCRSLSSSTCGAQDSSPFSLESPASPASTAKPNYRIMVEVSLKKEAG-VGLGIGLCSIPYFQCISG--------------------VFIHTLSPGSVAHLDGRLRCGDEIVEINDSPVHCMTLNEVYTILSHCDPGPVPIIVSRHPDPQVSEQQLK--------------EAVAQAVEGVKFGKERHQWSLEG----VKRLESSWHGRPTLEKEREK-HSAPPHRRAQKIMVRSSSDSSYMSGSPGGSP-----------CSAGAELQPSEGEGSTHSP-SLPPGEEQEPCPGVPSRPH---QESPP-LSESLERDSHPPLKLKNSFEILVRKPTSTKPKPPPRKYFKNDSEPQKKLEEKEKVTDPSGHTLPTCSQETRELLP---------------------LLL-QEDTAGRTLCTAACCPGPAASTQTSSSTEGEP-RRSASPETPAS-PGKHPLLKRQARMDYSFDSTTEDPWVRISDCIKN--LFSPIMSENHSHMPLQPNASLGEEDGTQGHPEGGLSKMDTANGAPRIFKSADGSTVKKGPPVAPKPAWFRQSLKGLRNRVPETRRAPEVASAIQTTPVSRDASGPQSQASSSS--IRQRISSFENFGSSQLPDRGVQRLS----------------------------------------------------------LQPTSGETTRLPGKQDEGRFSGLPAQGTKVT-----AKHRQTEVEPPSTTFP----------------------NSSEVGDPDMSESPPPGQRPNPKALSP--DPLLRLLTTQ----TEDTQGPGFKMPSQRARSFPLTRTQS-----YETKLLDEKSSKLYSISSQLSSAVMKSLLCLPSSASCGQITCIPKERVSPKS-PCNNSAAAEGFGEAVASDT---GFSLNLSELREYSEGLTEPGETEDRN------HCSSQAGQSVISLLSAEELKKLIEEVRVLDEATLKQLDSIHVTVLHKEEGAGLGFSLAGGADLENKVITVHRVFPNGLASQEGTIQKGNEVLSINGKSLKGATHNDALAILRQARDPRQAVIVTR---------------------------------KAIVEAAHDLNSSTDSAASASVASGISVES--------------------------------------------------------------------VEATVCTVTLEKTSAGLGFSLEGGKGSLHGDKPLTINRIFKG--TEQGDAVQPGDEILQLAGTAVQGLTRFEAWNVIKALPDGPVTVVIRRNGLEGKQTTASADL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O54824-1", "uniprot_id": "IL16_MOUSE", "id": "O54824-1", "name": "Pro-interleukin-16", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEPHGHSGKSRKSTKFRSISRS--LILCNAKTSDDGS-------------------------------SPDEKYP-DPFETSLCQG-------------KEGFFHSSMQLADTFEAGLSNIPDLALASDSAQLAAAGSDRGKHCRKMFFMKESS---------STSSKEKSGKPEAQ----SSSFLFP--------------------KACHQRTRSNSTSVNPYSAGEIDFPMTKKSAAP--TDRQPYSLCSNRKSLSQQLDYP---ILGTARPTRSLSTAQLGQLSGGLQASVISN-------------------------------------------IVLMKGQAKGLG----------------FSIVGGKDSIYGPIGIYVK-----------------SIFAGGAAAADGRLQEGDEILELNGESMAG-------------------------------------------------------------------------------------------------------------------LTHQDALQKFKQAKKG-------------------------------------------LLTLTVRTRLTTPPSLCSH---------------------------------------------------------------------------LSPPLCRSLSSSTCGAQDSSPFSLESPASPASTAKPNYRIMVEVSLKKEAG-VGLGIGLCSIPYFQCISG--------------------IFVHTLSPGSVAHLDGRLRCGDEIVEINDSPVHCLTLNEVYTILSHCDPGPVPIIVSRHPDPQVSEQQLK--------------EAVAQAVEGVKFGKDRHQWSLEG----VKRLESSWHGRPTLEKEREK-HSAPPHRRAQKIMVRSSSDSSYMSGSPGGSP-----------CSAGAEPQPSEREGSTHSP-SLSPGEEQEPCPGVPSRPQ---QESPP-LPESLERESHPPLRLKKSFEILVRKPTSSKPKPPPRKYFKNDSEPQKKLEEKEKVTDPSGHTLPTCSQETRELLP---------------------LLL-QEDTAGRAPCTAACCPGPAASTQTSSSTEGES-RRSASPETPAS-PGKHPLLKRQARMDYSFDITAEDPWVRISDCIKN--LFSPIMSENHSHTPLQPNTSLGEEDGTQGCPEGGLSKMDAANGAPRVYKSADGSTVKKGPPVAPKPAWFRQSLKGLRNRAPDPRRPPEVASAIQPTPVSRDPPGPQPQASSS---IRQRISSFENFGSSQLPDRGVQRLS----------------------------------------------------------LQPSSGETTKFPGKQDGGRFSGLLGQGATVT-----AKHRQTEVESMSTTFP----------------------NSSEVRDPGLPESPPPGQRPSTKALSP--DPLLRLLTTQ----SEDTQGPGLKMPSQRARSFPLTRTQS-----CETKLLDEKASKLYSISSQLSSAVMKSLLCLPSSVSCGQITCIPKERVSPKS-PCNNSSAAEGFGEAMASDT---GFSLNLSELREYSEGLTEPGETEDRN------HCSSQAGQSVISLLSAEELEKLIEEVRVLDEATLKQLDSIHVTILHKEEGAGLGFSLAGGADLENKVITVHRVFPNGLASQEGTIQKGNEVLSINGKSLKGATHNDALAILRQARDPRQAVIVTR---------------------------------RTTVEATHDLNSSTDSAASASAASDISVES--------------------------------------------------------------------KEATVCTVTLEKTSAGLGFSLEGGKGSLHGDKPLTINRIFKG--TEQGEMVQPGDEILQLAGTAVQGLTRFEAWNVIKALPDGPVTIVIRRTSLQCKQTTASADS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14005-1", "uniprot_id": "IL16_HUMAN", "id": "Q14005-1", "name": "Pro-interleukin-16", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MESHSRAGKSRKSAKFRSISRS--LMLCNAKTSDDGS-------------------------------SPDEKYP-DPFEISLAQG-------------KEGIFHSSVQLADTSEAGPSSVPDLALASEAAQLQAAGNDRGKTCRRIFFMKESS---------TASSREKPGKLEAQ----SSNFLFP--------------------KACHQRARSNSTSVNPYCTREIDFPMTKKSAAP--TDRQPYSLCSNRKSLSQQLDCPAGKAAGTSRPTRSLSTAQLVQPSGGLQASVISN-------------------------------------------IVLMKGQAKGLG----------------FSIVGGKDSIYGPIGIYVK-----------------TIFAGGAAAADGRLQEGDEILELNGESMAG-------------------------------------------------------------------------------------------------------------------LTHQDALQKFKQAKKG-------------------------------------------LLTLTVRTRLTAPPSLCSH---------------------------------------------------------------------------LSPPLCRSLSSSTCITKDSSSFALESPSAPISTAKPNYRIMVEVSLQKEAG-VGLGIGLCSVPYFQCISG--------------------IFVHTLSPGSVAHLDGRLRCGDEIVEISDSPVHCLTLNEVYTILSHCDPGPVPIIVSRHPDPQVSEQQLK--------------EAVAQAVENTKFGKERHQWSLEG----VKRLESSWHGRPTLEKEREK-NSAPPHRRAQKVMIRSSSDSSYMSGSPGGSP-----------GSGSAEKPSSDVDISTHSP-SLPLAREPVVLSIASSRLP---QESPP-LPES--RDSHPPLRLKKSFEILVRKPMSSKPKPPPRKYFKSDSDPQKSLEERENSSCSSGHTPPTCGQEARELLP---------------------LLLPQEDTAGRSPSASAGCPGPGIGPQTKSSTEGEPGWRRASPVTQTS-PIKHPLLKRQARMDYSFDTTAEDPWVRISDCIKN--LFSPIMSENHGHMPLQPNASLNEEEGTQGHPDGTPPKLDTANGTPKVYKSADSSTVKKGPPVAPKPAWFRQSLKGLRNRASDPRGLPDPALSTQPAPASREHLGSHIRASSSSSSIRQRISSFETFGSSQLPDKGAQRLS----------------------------------------------------------LQPSSGEAAKPLGKHEEGRFSGLLGRGAAPT-----LVPQQPEQ-VLSSGSP----------------------AASEARDPGVSESPPPGRQPNQKTLPPGPDPLLRLLSTQ----AEESQGPVLKMPSQRARSFPLTRSQS-----CETKLLDEKTSKLYSISSQVSSAVMKSLLCLPSSISCAQTPCIPKEGASPTS-SSNEDSAANGSAETSALDT---GFSLNLSELREYTEGLTEAKEDDDGD------HSSLQSGQSVISLLSSEELKKLIEEVKVLDEATLKQLDGIHVTILHKEEGAGLGFSLAGGADLENKVITVHRVFPNGLASQEGTIQKGNEVLSINGKSLKGTTHHDALAILRQAREPRQAVIVTR---------------------------------KLTPEAMPDLNSSTDSAASASAASDVSVEST-------------------------------------------------------------------AEATVCTVTLEKMSAGLGFSLEGGKGSLHGDKPLTINRIFKGAASEQSETVQPGDEILQLGGTAMQGLTRFEAWNIIKALPDGPVTIVIRRKSLQSKETTAAGDS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QCG1-1", "uniprot_id": "A0A8M9QCG1_DANRE", "id": "A0A8M9QCG1-1", "name": "Pro-interleukin-16", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLSFERPPPLAAMHAGREPPSVAIQPLRNTHPQRRRTKRMERGKAG--LSSKKLAVLSRSLLICSSSAHEDASSPEEKYREPWDVPLEDRRPDGTLMSRSVSVQTSYRGHEGPKRAMRRSFSIKETSFWRMCVATRDDALH-------------------------------TADRKLQNCDNEASVAQDLH-----------RETYIYFGERLAPFNGQVINEQPNPEPDLHKHKTTESRNTSSKAFTENRALFTNT---------TESQQLGYGYGEKEPMGNNNNLQMPSIKVSDDDVKNIDNEDQGCQEMSCKRSRSNSTSVHPYWIGDLETIIMKTPELFPCSAHNTAAFYGNRKSLSQQLEFPHSVPQAVVRPSRSLSSAHLVPSCSSVQAFIISN-------------------------------------------IVLMKGHGKGLG----------------FSIVGGRDSMYGPMGIYVK-----------------TIFPGGAAAADGRLQEGDEILELNGESLHG-------------------------------------------------------------------------------------------------------------------LTHEDALHKFKQVKKG-------------------------------------------LLTLVVRTSLRVGAVMGSHG--------------------------------------------------------------------------QASQLCRSRSLSSSTAISRVSADLGEYNCLNNPAKAQDRVMMEITLHKEFG-VGLGIGLCCVPSSGGCPG--------------------IYIHTLSPGSVAHMDGRLRCGDEIMEINETVVCNMTLNDVYTVLSQCSPGPVHIIISRHPDPKVSEQQLN--------------EAISQAVENSRLRKDRSQWSMDGCNSSLRRPESCCHSRQKCMRCVDRSTSQLTCRRTQKPMIRSCSEGAYSQRCCIPNS-----------TTAQSFLHTDHVSLTTNSETSLNNTLSQSSFTDDDYNIP---YKCPVNFNGKQTFDVNASSGLVNQPRKYYRQQQEVSSQE-ALNVSSGSSRDSPVKEEDLMLSQSNCQFFCSLYRALRKISR---------------------LLFKNEVVEHAELGTKASACIS--EPKSDSTHRGDRLHKDPECSSQVCGSSKRVGLRRQAHLEVSTDQP-LDPWVKLTDSPENQSYCSKTMSDHNGDSEVNGTASETTES-----------------------KSEQATSVKKGPPVAPKSARARQSMKSIRSGKPITEALRNQQDNRSHETGRTFGISSRAASSGGNLSIRQKISSFETFSSPDGSERPSWRMAPTASVPPTEKTTKTSSADYSNADRTRVNTSNLRNNDYCQSTPPISATTLPSEEHSTSLILESHPEVEKQSTSHDSETCKSIPVEEPTVDPTEEITTAVETEQELVSSAKSSVDTEHEPVSSAETEQEPVSSTKSSVETEPVTSAETKQEPVSSEKDLPSVTHVPRRSSSSKEA-PGEKAEEAGTHAVSLRTRSLPLSPSSDGP---ISSGLEGESLGIILSFSNQVSSALMRSMQSLPQSPCIRLGNPWSAPPGSPLHNPIEEDSAAENPHASTALENNEKGFSVSLAELRERTIERGEECKTDDWKPEQALTSASAACAQSMLSVLPQPEIQRMIQEVKDLDEDTLRQLEDIHVVILHKEEGAGLGFSIAGGIDLENKATTVHRVFPSGLAAQEGTIEKGDEVLSINGQTLKNVTHSDATAILRQSRTLKQAVVVVS---------------------------------KNKDAEGKSAN-ANESSCSGGAESSIAGDD---------------------------------------------------------------------GGEVVTFELEKNAGGVGFSLEGGKGSISGDRPLAVNRIFTGSDAEQK-GLKSGDEVLQIQDSSLQGLTRFEAWTLIKNLNDGPFTLIVKRR--RCEQS------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VUE8-1", "uniprot_id": "Q9VUE8_DROME", "id": "Q9VUE8-1", "name": "", "aln": "MASTPKANGTTAKTATINDDYITVVEVDDPTSNPKDRLKKLVKRQSSVAEDSSFITVLTINEMELLQQRKKEEDVGSGSSPTMEEQIENVTVFRLPGERLGFGLKFQGGTRSTELVQKLYIQSCAADSPASKVSTSWGNLREGDEIVSIDGRDVRELTRIDCVRGLKDNVAIKLVVRNGHGQKPPSEEDPQQQEHLSITLNAQPPPPPPVPPRKLVRRQNSKENQAQLLIEKPLTPPPDAEYYLNLLTESIKAGSESDDTASTISTVIDKFSVGSNYSSDSSLNGHELAKVLQPFTLLEQEFLPLEQPLGHPKLLIPGNNYENVEFKTEKVNVYENVELRSPETTPTPKPRVQLATVEPKKRSIIPMPRKIPTPTKLPIEVTPPRVPILEEPKTPTNNKVDSPKTPTNELKESPISATKIPKAKFSRAKTEGEIKLHLPAPKQQSPQSKSRIPIVSTPTAQKTVPKPVSPTMNGTPLSSNIPRLLQKQKSETDLKLNLYRSKSKESSPRPPLQRANSAEAPERTFIPVLLNGNSKSSNSLESVSSIGSSSSGNSVRSPKGPKPKPPERVQSLQKTQIPKLQALPTTPPQQIPKLSMQTFKQSPPTPRSTPVGTPSPTSNREIRFKIQTYESKTQDEDKLPSLFDLVHSQENDKDKDRDSDSLKTHNSITALLAAAAAEAADLSRESPPPLVVGKCMKIVDDTNTTTCYTSSSSGEEDEDDLDASNREYICEDGEKLGPPELINGPGPSEAYFNMFWHSNMLPTIGEVEEEFSSLEPQSLTNGNLVKSEESKKLPKMEVNAGGLAQLTDDKIADHDASATRADTRDEVTTNQTQEISSSSSSSVKSQKTTTTTRVTTTKTSSSSSSSSCSSTVIPDVAFKLQPYEERDDILSEPITTIHEERRVLSEQKTLSESRTRDALTGEEQLVTSANSKSSSARFKKISSNDNLLDLGDEQDMQEQPLTATITQESSLRERLECPQDNQSIDRGTLTLSERGKQLSEKEGLTTYTECETSEKESYLEGQQVLNGKGGFVSQDENSDQPTYEREVSETLTIVNDGEKQVTKKLEQNKEIAGKKGAKLLKKTDEERRLEQEAQKLIESYQKVKKEAEKLYKLELADDDQGFDLSAFEQAEEEDKPEVSEEIKEVKDSQPVKVDIQIEEEVKTPNQVIGEVKVEDVNKEIKETVQVSQQEIKKEVKVSHQETKETFKSEEKDESNELKIVKEEVKVTHQDLREQIQEIEAVKVVHKEVKVIKESAKVTTTTSHKQATKEVIISKEDHKNDSALPAVSTTKVEIISPPLEDDLGYVLHKHIIFPQEKVKTAPTPLPKPKPKPPVPTNKPKMPVNLTKPKSAPPPVPSKRSELSGSGGKPTPTQRRGSLETAQPPKPLERIIVGVEQRDEPEKPQPIINLASVDLPNVAPNSKQATVETTPVVEMPPDELQFESHQLPDDGEKEKDLHQESNDLLSGSSSSSVTTPITTPILVSATSSMDSVQSVIEVVNGMPIISNQQTDDDDIDEVAAYDDGMHLEAEGTKDVRPVQEVTTLTLDREHESDLGTLSNHHSNISSISGINASSNIPAATLISSSIKKTSTEAATTKPAAPQIPGKMELLSSNTGTTTTTTTATHHLHQATTTKQLLVQDYLSYASPPTYSRLPPDGHEFPPNFSEPLIMHSHPLKVTTELSYEIQKGGKDESSAPPLPKTGPPATVPRKVYRQDLVINVEPAPSLTRDYQRSLSGGTPRKPSDWRKDEKSEKSVRDKIAMFSSNNELDAIPPAPATAPISSSFTRKPLNRSSENLLDSCSSSSAPSLKTRAMSVENLNDVQRQYQLAKQLPQLHVADSMYSLNTATPTPSYASLPRRSHGGSYSSGVERRISFSGEGGDAANRKAAITNILEQRRRSLSKLRGLVIPERPQLLEPILDLPEIKSQVKAASGEDSTDSGLGESHRSTVNRNCQLGAGGAANNYRSILNTNQRRPLEQQLSQPPAKPPRTSLTPLQPRSMMIPPPPPPLDQESDTDSVFSHTARVATPPEKFALTRTLSSETNTSIASSNTSTLTSGSSAGSQASCSSLGSTPAVDLTRRVLKSQVINGEAVALSSRKSILASAKCRSAKSRGQEEDNDSTDGEACSLANRRMKPISSYKLQQQQIQLGKQLVVDKLINVAAYVELTSDTDDSSRRSDTPAKISAMFIDEERKASFKGDPNQQAKVKVEQVKPMVLPMLLPSAKREPLKQQTTAELREKFERSAAAQAQTQNHSPVIHKVTQKPHHERFSSLDSLASSSSGVSSTTQNVSTTQETATEFGSFSSLGSNQSLITAQDVQQIVEEA----DPPLKTPEAFIIVLQRENPESSIGITLAGGSDYEAKEITIHKILSNTPAAKDGRLKKGDRILAVNGMSMRGLTHRESISVLKTPRPEVVLVVTRSESLVVKALTKKRSSLGSLSSLNEKPTELDYERKRNYHKASRSLDLDLDLVSNEAGESPVATTPSTGSVSPPQPASLHDEDAEATIAGIRARRQLSRGDAAKLSTSELLERAAEARNAIAAEIRAQAEDAAASGGGARCVEIVKDSCGLGFSIEGGFDSPLGNRPLIVKKVFMGGAAQKTNQVRNGDEILSINGASTSRMTRVDAWNYMKQLPLGPVKICFA---------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .. . .* : . . * *.. . :.:. : . .. : . . . .: . : .: . :.: . ... : *.*:* . :: : . :: :*: **:* . . ..* :: ... : ** : :. :.* *. * : *:: : * *: : :*. .* . :*::..** :* .: ::*::: ..**. :*. :* .. . : *: .. : . * : . . ...*. *::: : :.* *.*..: .. . * *. .. . * : ...* : ..: * . : . : . . :* : * :*:** . . ::..:. : :: ::: * *.. . : . . .. : ::.::.: . . . : : . . :* : * . . : * : . :. : : . .. : : .: . : . :: .: : * . . .:. . .: . : . : :.. :: . : . * ::::*. . : * : : . :. : * * *: . :.: .: . . . . : .. .: * ::. :: : : :. . . . . : . * :. . .. * . : : : . * * . * . : .: : .: .*:.. :: : .. . : .: .. . :. .* .* . : . : . * . * *::. :::::::*. : .*: : : :.: ::: :.:*:::*** * * * *:*:::.. *:::* ::**:.:*::** :::. ** :: ::*: .* *:. : . : : .. . * :: . . . : * : *:***:*** .* *::** ::::* * ::: :: ***:*.: .:: . :**.:**. :* * **..: . ", "identical_positions": 121, "similar_positions": 417, "identity": "4.56%" }, { "cls_id": "homologset.agr.MGI:1270856", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AXZ6-1", "uniprot_id": "PRS40_RAT", "id": "Q6AXZ6-1", "name": "Serine protease 40", "aln": "MWGSRAQQSGPDRGRTCLLAVLLLSFSLFQLHAQDYKPSQTPPPTSDALLKPMGRVQKEICGKTKFQGKIYGGSIAKAERWPWQASLIFRGRHICGAVLIDKNWVASAAHCFKRSLKPSDYRILLGYNELSNPSNYSRQMTLSKVIVHEDYNKLHSQEKDIVLIQLHLPVRYSSHIFPVCVPDQTTKEPSDESCWISGWG---MVTDDKFLQAPFPLLDSEVFLMNDQECEAFFQTPQISITEYDAIKDDMICAGDITNQKSTCRGDSGGPLVCLLDSYWYLVGLASWSGACLEPIHSPSIFTRVSHFSDWIEKKKADTPDVDPSLAPLEETAPSLIGWRNYSAGTTLEPRICTTLLSSQVLLLQSIWLRIL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70169-1", "uniprot_id": "PRS39_MOUSE", "id": "O70169-1", "name": "Inactive serine protease 39", "aln": "MWGSRAQQSGPDRGGACLLAAFLLCFSL--LHAQDYTPSQTPPPTSNTSLKPRGRVQKELCGKTKFQGKIYGGQIAKAERWPWQASLIFRGRHICGAVLIDKTWLLSAAHCFQRSLTPSDYRILLGYNQLSNPSNYSRQMTVNKVILHEDYSKLSRLEKNIVLIQLHHPVIYSTHIFPACVPDGTTKVSPNNLCWISGWG---MLSADKFLQAPFPLLDAEVSLIDEEECTTFFQTPEVSITEYDVIKDDVLCAGDLTNQKSSCRGDSGGPLVCFLNSFWYVVGLANWNGACLEPIHSPNIFTKVSYFSDWIKQKKANTPAADVSSAPLEEMASSLRGWGNYSAGITLKPRISTTLLSSQALLLQSIWLRIL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AB32TJN5-1", "uniprot_id": "A0AB32TJN5_DANRE", "id": "A0AB32TJN5-1", "name": "", "aln": "MWWKTC------------VTLLLLMYVR----------------DSLSNLQVCGRPNPTLN------PRIVGGVNATHGAWPWMVSLQGRYGHFCGGSLINNQWVLTAAHCIVDET-PSSIIVYLGKWRSYVADVNSISRTIRHIIPHPSYSNITK-DNDIALLQLTSTVQYTDYIKPICLADENSNFPRGTNSWVAGWGDIGVLGTGGIRGRTTVSVPLPHPGILQEAELKVYSNADCNNICHGRITPNMICAGTRRGGKATFSGDSGGPLMTKCS-VWVQAGVLSHGYGCAQPN-LPEVFIRVSEYKQWITGNVG----------------------GNLPGFVLFDPRCSLHKVLNRVFCCFG------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** . . :: :** : * : *: ** : : :* ** *. *** .** * *:**. **:: *: :****: . **. : ** . .. * . *: ::* * .*.:: :::*.*:** .* *: :* * *:.* .:: . . .*::*** :: . : . : : :: .:...: . :. *. :::*** . *:: *******: . * .*: . . .* :* *.:* :** :.:** : . * .. :.** . : .:.: . ", "identical_positions": 76, "similar_positions": 104, "identity": "20.43%" }, { "cls_id": "homologset.agr.MGI:1270859", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q923I8-1", "uniprot_id": "CRY2_RAT", "id": "Q923I8-1", "name": "Cryptochrome-2", "aln": "------------------------------------------------------MAAAAVVAATVPVQSMGADGASSVHWFRKGLRLHDNPAL---------LAAVRGARCVRCVYILDPWFAASSSVGINRWRFLLQSLEDLDTSLRKLNSRLFVVRGQP-------ADVFPRLFKEWGVTRLT-----FEYDSEPFGKERDAAIMKMAKEAG-VEVVTENSHTLYDLDRIIELNGQKPPLTYKRFQALISRMELPKK-PVGAVSSQHMEN-CRAEIQENHDDTYGVPSLEELGFPTEGLGPAVWQGGETEALVRLDKHLERKAWVANYERPRMNANSLLASPTGLSPYLRFGCLSCRLFYYRLWD-----LYRKVKRNSTPPLSLFGQLLWREFFYTAATNNPRFDR-MEGNPICIQIPWDRNPEALAKWAEGKTGFPWIDAIMTQLRQEGWIHHLARHAVACFLTRGDLWVSWESGVRVFDELLLDADFSVNAGSWMWLSCS-AFFQQFFHCYCPVGFGRRTDPSGDYIRRYLPKLKGFPSRYIYEPWNAPESVQKAANCIIGVDYPRPIVNHAETSRLNIERMKQIYQQLSRYRGLCLWASVPSCVEDLSHPVAEPGSSQAGSISNTGPRPLSSGPASPKRKLEAAEEPPGEELSKRARVTVTQMPAQEPPSKDS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R194-1", "uniprot_id": "CRY2_MOUSE", "id": "Q9R194-1", "name": "Cryptochrome-2", "aln": "------------------------------------------------------MAAAAVVAATVPAQSMGADGASSVHWFRKGLRLHDNPAL---------LAAVRGARCVRCVYILDPWFAASSSVGINRWRFLLQSLEDLDTSLRKLNSRLFVVRGQP-------ADVFPRLFKEWGVTRLT-----FEYDSEPFGKERDAAIMKMAKEAG-VEVVTENSHTLYDLDRIIELNGQKPPLTYKRFQALISRMELPKK-PAVAVSSQQMES-CRAEIQENHDDTYGVPSLEELGFPTEGLGPAVWQGGETEALARLDKHLERKAWVANYERPRMNANSLLASPTGLSPYLRFGCLSCRLFYYRLWD-----LYKKVKRNSTPPLSLFGQLLWREFFYTAATNNPRFDR-MEGNPICIQIPWDRNPEALAKWAEGKTGFPWIDAIMTQLRQEGWIHHLARHAVACFLTRGDLWVSWESGVRVFDELLLDADFSVNAGSWMWLSCS-AFFQQFFHCYCPVGFGRRTDPSGDYIRRYLPKLKGFPSRYIYEPWNAPESVQKAAKCIIGVDYPRPIVNHAETSRLNIERMKQIYQQLSRYRGLCLLASVPSCVEDLSHPVAEPGSSQAGSISNTGPRALSSGPASPKRKLEAAEEPPGEELTKRAR--VTEMPTQEPASKDS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q49AN0-1", "uniprot_id": "CRY2_HUMAN", "id": "Q49AN0-1", "name": "Cryptochrome-2", "aln": "-----------------------------------------------------MAATVATAAAVAPAPAPGTDSASSVHWFRKGLRLHDNPAL---------LAAVRGARCVRCVYILDPWFAASSSVGINRWRFLLQSLEDLDTSLRKLNSRLFVVRGQP-------ADVFPRLFKEWGVTRLT-----FEYDSEPFGKERDAAIMKMAKEAG-VEVVTENSHTLYDLDRIIELNGQKPPLTYKRFQAIISRMELPKK-PVGLVTSQQMES-CRAEIQENHDETYGVPSLEELGFPTEGLGPAVWQGGETEALARLDKHLERKAWVANYERPRMNANSLLASPTGLSPYLRFGCLSCRLFYYRLWD-----LYKKVKRNSTPPLSLFGQLLWREFFYTAATNNPRFDR-MEGNPICIQIPWDRNPEALAKWAEGKTGFPWIDAIMTQLRQEGWIHHLARHAVACFLTRGDLWVSWESGVRVFDELLLDADFSVNAGSWMWLSCS-AFFQQFFHCYCPVGFGRRTDPSGDYIRRYLPKLKAFPSRYIYEPWNAPESIQKAAKCIIGVDYPRPIVNHAETSRLNIERMKQIYQQLSRYRGLCLLASVPSCVEDLSHPVAEPSSSQAGSMSSAGPRPLPSGPASPKRKLEAAEEPPGEELSKRAR--VAELPTPELPSKDA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q0E8P0-1", "uniprot_id": "Q0E8P0_DROME", "id": "Q0E8P0-1", "name": "", "aln": "---------------------------------------------------------------------MDSQRSTLVHWFRKGLRLHDNPALSH---IFTAANAAPGKYFVRPIFILDPGILDWMQVGANRWRFLQQTLEDLDNQLRKLNSRLFVVRGKP-------AEVFPRIFKSWRVEMLT-----FETDIEPYSVTRDAAVQKLAKAEG-VRVETHCSHTIYNPELVIAKNLGKAPITYQKFLGIVEQLKVPKV-LGVPEKLKNMPTPPKDEVEQKDSAAYDCPTMKQLVKRPEELGPNKFPGGETEALRRMEESLKDEIWVARFEKPNTAPNSLEPSTTVLSPYLKFGCLSARLFNQKLKE-----IIKRQPKHSQPPVSLIGQLMWREFYYTVAAAEPNFDR-MLGNVYCMQIPWQEHPDHLEAWTHGRTGYPFIDAIMRQLRQEGWIHHLARHAVACFLTRGDLWISWEEGQRVFEQLLLDQDWALNAGNWMWLSAS-AFFHQYFRVYSPVAFGKKTDPQGHYIRKYVPELSKYPAGCIYEPWKASLVDQRAYGCVLGTDYPHRIVKHEVVHKENIKRMGAAYKVNREVR---------TGKEEESSFEEKSETSTSG-----------------KRKVRRATG----SAPKRKR----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P05066-1", "uniprot_id": "PHR_YEAST", "id": "P05066-1", "name": "Deoxyribodipyrimidine photo-lyase, mitochondrial", "aln": "MKRTVISSSNAYASKRSRLDIEHDFEQYHSLNKKYYPRPITRTGANQFNNKSRAKPMEIVEKLQKKQKTSFENVSTVMHWFRNDLRLYDNVGLYKSVALFQQLRQKNAKAKLYAVYVINEDDWRAHMDSGWKLMFIMGALKNLQQSLAELHIPLLLWEFHTPKSTLSNSKEFVEFFKEKCMNVSSGTGTIITANIEYQTDELYRDIRLLENEDHRLQLKYYHDSCIVAPGLITTDRGTNYSVFTPWYKKWVLYVNNYKKSTSEICHLHIIEPLKYNETFELKPFQYSLP--DEFLQYIPKSKWCLPDVSEEAALSRLKDFLGTKSSKYNNEKDMLYLG----GTSGLSVYITTGRISTRLIVNQAFQSCNGQIMSKALKDNSSTQNFIKEVAWRDFYRHCMCNWPYTSMGMPYRLDTLDIKWENNPVAFEKWCTGNTGIPIVDAIMRKLLYTGYINNRSRMITASFLSK-NLLIDWRWGERWFMKHLIDGDSSSNVGGWGFCSSTGIDAQPYFRVFNMDIQAKKYDPQMIFVKQWVPELISSEN-------KRPE------------NYPKPLVDLKHSRERALKVYKDAM----------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: :****:.***:** .* . : ::::: . : *: :*::*: .* :*: *:: . :. :. * .:**. : : : : * : : : :.: . : : . : .: : : :: * : : * : . *. * .:: .* ** *:.. * : . *: . ..: ** *: * :* **: : : : : :.. .. .:: :: **:*: * . * . ::* *:.:* : * *.** * :**** :* *:*:: :* .*.**:: :* :.*. * * * : *:* * : *.*.* : *.: : :*: : .:: **. ::::::*:* : . :**: :*. . :: ", "identical_positions": 81, "similar_positions": 149, "identity": "11.93%" }, { "cls_id": "homologset.agr.MGI:1270860", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O15162-1", "uniprot_id": "PLS1_HUMAN", "id": "O15162-1", "name": "Phospholipid scramblase 1", "aln": "----------------------------------------------------------------------MDKQNSQMNASHPETNLPVGY---PPQYPPTAFQGPPG-YSG--------------------YPGPQVSYPPPPAGHSGPGPAGFPVPNQPVYN----------QPVYN---QPVGAAGVPWMPAPQPPLNCPPGLEYLSQIDQILIHQQIELLEVLTGFETNNKYEIKNSFGQRVYFAAED----TDCCTRNCCGPSRPFTLRIIDNMGQEVITLERPLRCSS-CCCPCCLQEIEIQAPP----------GVPIGYVIQTWHPCLPKFTIQNEKREDVLKISGPCVVCSCCGDVDFEIKSLDEQCVVGKISKHWTGILREAFTDADNFGIQFPLD----------------LDVKMKAVMIGACFLIDFMFFESTGSQEQKSGVW------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9NRY7-2", "uniprot_id": "PLS2_HUMAN", "id": "Q9NRY7-2", "name": "Phospholipid scramblase 2", "aln": "----------------------------------------------------------------------MRSWNSLFCLNSSR--------------PPGHIVYPKH-QAG--------------------HTGKQADHLGSQAFYPG-RQHDYLVPPAGTAG----------IPVQN---QPGRPEGVPWMPAPPPPLNCPPGLEYLSQIDMILIHQQIELLEVLFSFESSNMYEIKNSFGQRIYFAAED----TNFCIRNCCGRSRPFTLRITDNVGREVITLERPLRCNC-CCCPCCLQEIEIQAPP----------GVPVGYVTQTWHPCLTKFTIKNQKREDVLKISGPCIVCSCIAGVDFEITSLDEQIVVGRISKHWSGFLREAFTDADNFGIQFPRD----------------LDVKMKAVMIGACFLIDYMFFERTR---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P58195-1", "uniprot_id": "PLS1_RAT", "id": "P58195-1", "name": "Phospholipid scramblase 1", "aln": "----------------------------------------------------------------------MEKHGPPEHAAYPIPQADYQGSQGPYPGPQGPYPGPQGPYAGPQGP----------------YPGPQGPYAGPQGPYPG-PQPGYPVPPGSYAGGDPSGFPVQHQPAYN---HPGGPGGTPWMQAPPPPLDCPPGLEYLTQIDQILVHQQIELLEVLTGFETNNKYEIKNSLGQRVYFAVED----TDCCTRNCCGASRPFTLRILDNMGREVMTLERPLRCSS-CCFPCCLQEIEIQAPP----------GVPVGYVIQTWHPCLPKFTLQNEKRQDVLKVVGPCVVCSCCSDIDFELKSLDEESVVGKISKQWSGFVREAFTDADNFGIQFPLD----------------LDVKMKAVMLGACFLIDFMFFERTGNEEQRSGVW------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DCW2-1", "uniprot_id": "PLS2_MOUSE", "id": "Q9DCW2-1", "name": "Phospholipid scramblase 2", "aln": "----------------------------------------------------------------------MEAPRSGTYLPAGYAP----------QYPPAAVQGPPE-HTG--------------------RPTFQTNYQVPQSGYPG-PQASYTVSTSGHEG-----YAATRLPIQNN--QTIVLANTQWMPAPPPILNCPPGLEYLNQIDQLLIHQQVELLEVLTGFETNNKFEIKNSLGQMVYVAVED----TDCCTRNCCEASRPFTLRILDHLGQEVMTLERPLKCSS-CCFPCCLQEIEIQAPP----------GVPIGYVTQTWHPCLPKLTLQNDKRENVLKVVGPCVACTCCSDIDFEIKSLDEVTRIGKITKQWSGCVKEAFTDSDNFGIQFPLD----------------LEVKMKAVTLGACFLIDYMFFEGCE---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9VT88-1", "uniprot_id": "Q9VT88_DROME", "id": "Q9VT88-1", "name": "Phospholipid scramblase", "aln": "MKSNVNQGGYAPPGFGSGFQPNAPPAEGFGYPPPTGGHNAPYPPAPGHPQPPPPTNYGFMPGPQPAGYAPVPQMPPYGEAPPYGAGQPPYMGGPGGQPPYAGGPGGQPPYVGGPGGQPHYGGGAPPPQAFGGYPPGPAGPGGPPNAFGGYPPGQPQQPIVTQPG---------MGPGMGPGMAPQGGPAGDWMSIPTGIPNCPRGLEYLTTIDQLLVKQKVELLEAFTGFETNNKFTIKNALGQKVYFAAED----NDCCTRNCCGPARPFDMRVFDNFQQEVIHMHRPLACSS-CLFPCCLQSIEVSAPP----------GNVIGTIEQEWSICSPSFRILNHVGDTVMRIEGPFCTFSLCGDVEFNVVSLTGE-KIGKISKQWSGLAREIFTDADFFGINFPLD----------------LDVRMKAVLLGATFLIDAMFFEKAGNQETDRPGML-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VZW1-1", "uniprot_id": "Q9VZW1_DROME", "id": "Q9VZW1-1", "name": "Phospholipid scramblase", "aln": "----------------------------------------------------------------------MMQMSEYKVLPQN-----------------------------------------------------------APQDENGAVVLQPQAANVGNNA---------NGP-------------ENWMSIPVGMPNCPQGLEYLTALDQLLVSQKIEKLELLTGFETKNRFKVKNSLGQNVYFAYEE----SDCCTRNMLGRSRPFEMKILDNFQNEVLHLYRPFKCDILCCFPSCMNAVEVSAPP----------GQVIGSVEQVCTFMRPKFNIKNTCGDTVLQIEGPVCPCKCFSDTNFKVLSANNE-EIGKISKQWSGLGRELFTDADYFSVTFPLN----------------LDVRMKALIFAALFLIDAVYYEQ-----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P47140-1", "uniprot_id": "AIM25_YEAST", "id": "P47140-1", "name": "Altered inheritance rate of mitochondria protein 25", "aln": "----------------------------------------------------------------------MHRTAIFLTYRSCMRN----------------------------------------------FSTLSKTLTVSSGKVIRNGPFRRVIREKNQIT-----------------KAPSVKAFKENSNSGIIKVHDPIATTILNEP-TVIIERQIEFMNVFLGFEQANRYAIMDVNGNKIASMMERDFSITKAIMRQFYRLHRPFLVDVFDNWGNVIMTIKRPFSFINSHIKTIIPPSAYVDNGSDSTHYHDGKEGTTVGETIQNWHLWRRRYELFQKDGVEGSTFDQFGKIDAPFLSFDFPVTDADGK-IMASVDRNWVGLGREMFTDTGVYVVRFDSQRCFDNIYPTEMLSSQVLTLDQRAVLLANAVSIDFDYFSRHSRQTGGFLSFGGGYDE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . * . *. ::: :::* :: : .** * : : : *: : * .. *: *** : : *: . :: : **: . :. . * :* * : : . . :* : . :. : ::* * :* ***:. : : * : * : :*: :. . ** ::. ", "identical_positions": 30, "similar_positions": 63, "identity": "6.49%" }, { "cls_id": "homologset.agr.MGI:1270861", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97378-1", "uniprot_id": "I12R2_MOUSE", "id": "P97378-1", "name": "Interleukin-12 receptor subunit beta-2", "aln": "MAQTVRECSLALLFLFMWLLIKANIDVCKLGTVTVQPAPVIPLGSAANISCSLNPKQGCSHYPSSNELILLKFVNDVLVENLHGKKVHDHTGHSSTFQVTNLSLGMTLFVCKLNCSNSQKKPPVPVCGVEISVGVAPEPPQNISCVQEGENGTVACSWNSGKVTYLKTNYTLQLSGPNNLTCQKQCFSDNRQNCNRLDLGINLSPDLAESRFIVRVTAINDLGNSSSLPHTFTFLDIVIPLPPWDIRINFLNASGSRGTLQWEDEGQVVLNQLRYQPLNSTSWNMVNATNAKGKYDLRDLRPFTEYEFQISSKLHLSGGSWSNWSESLRTRTPEEEPVGILDIWYMKQDIDYDRQQISLFWKSLNPSEARGKILHYQVTLQEVT-KKTTLQNTTRHTSWTRVIPRTGAWTASVSAANSKGASAPTHINIVDLCGTGLLAPHQVSAKSENMDNILVTWQPPKKADSAVREYIVEWRALQPGSITKFPPHWLRIPPDNMSALISENIKPYICYEIRVHALSESQGGCSSIRGDSKHKAPVSGPHITAITEKKERLFISWTHIPFPEQRGCILHYRIYWKERDSTAQPELCEIQYRRSQNSHPISSLQPRVTYVLWMTAVTAAGESPQGNEREFCPQGKANWKAFVISSICIAIITVGTFSIRYFRQKAFTLLSTLKPQWYSRTIPDPANSTWVKKYPILEEKIQLPTDNLLMAWPTPEEPEPLIIHEVLYHMIPVVRQP---YYFKRGQGFQGYSTSKQDAMYIAN-PQATGTLTAETRQLVNLYKVLESRDPDSKLANLTSPLTVTPVNYLPSHEGYLPSNIEDLSPHEADPTDSFD-LEHQHISLSIFASSSLRPLIF-GGERLTLDRLKMGYDSLMSNEA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1LRH7-1", "uniprot_id": "F1LRH7_RAT", "id": "F1LRH7-1", "name": "Interleukin-12 receptor subunit beta-2", "aln": "MAHTVRGCSLALIFLFMWLLIKANIDVCKLGTVTVQPAPVIPLGSTANISCSLNPKQGCSHYPSYNELILLKFVNDVLVEKLHGKKVHGHPSHSSIFQVTNLSLGMTLFVCKLNCSNSQKTQPVPVCGVEISVGVAPESPQSISCVQKGEHGTVACSWNSGKVTYLKTYYTLQLTGPNNVTYQNQCYSDNRQNCSRLDLGINLTPDLAESRFIVHVTATNDLGNSSSLLHTFTFLDIVRPLPPWDIRINFLNASGSRCTLQWEDEGQVVLNRLRYQPLNSTSWNMVNATNAKGRYDLQDLRPFTEYEFQISSKLHLSQGSWSNWSESLRTRTPEEEPVGTLDIWYMKQDIDCDRQQISLFWKSLNPSEARGKILHYQVTLQEVT-KKTTLQNTTRHTFWTGVIPRTGAWTASVSAANSKGTSAPTHINIVDLCGTGFLAPHQVSAKSGNMDNIMVTWQPPGKADSVIREYIVEWRALQQGSVMNLTPHWLRIPPYNMSALISEKIKPYICYEIRVHALSEDQGGCSSIRGDSSHKVPLSGPHITAITEKKESLFISWTHIPFLEQRGCILHYRIYWKERHSTAQPELCEIQYRHSQNSHPISSLQPKVTYVLWMTAVTAAGESPQGNEREFCPQGKANWKTFVISSICIAIIVVGTFSIRYFRQKAFTLLSTLKPQWYCRTIPDPANSTWVKKYPIMEEKIQPPMDNLLMAWSAPEEPEPLIINEVLYQMIPVGRQP---YCFKRGQGFQGYSTSKEDTIYLATNPQTTGTLTAESRQLVNLYKVLGSRDPDSKLGNLTSPLTVTPVNYLPTHEGYLPSNIEDLSSHEVDPSDSLD-LDHQHISLSIFASSSLRPLTF-CGERLTLDRLKMGYEK------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99665-1", "uniprot_id": "I12R2_HUMAN", "id": "Q99665-1", "name": "Interleukin-12 receptor subunit beta-2", "aln": "MAHTFRGCSLAFMFIITWLLIKAKIDACKRGDVTVKPSHVILLGSTVNITCSLKPRQGCFHYSRRNKLILYKFD----------RRINFHHGHSLNSQVTGLPLGTTLFVCKLACINSDE---IQICGAEIFVGVAPEQPQNLSCIQKGEQGTVACTWERGRDTHLYTEYTLQLSGPKNLTWQKQCKD---IYCDYLDFGINLTPESPESNFTAKVTAVNSLGSSSSLPSTFTFLDIVRPLPPWDIRIKFQKASVSRCTLYWRDEGLVLLNRLRYRPSNSRLWNMVNVTKAKGRHDLLDLKPFTEYEFQISSKLHLYKGSWSDWSESLRAQTPEEEPTGMLDVWYMKRHIDYSRQQISLFWKNLSVSEARGKILHYQVTLQELTGGKAMTQNITGHTSWTTVIPRTGNWAVAVSAANSKGSSLPTRINIMNLCEAGLLAPRQVSANSEGMDNILVTWQPPRKDPSAVQEYVVEWRELHPGGDTQVPLNWLRSRPYNVSALISENIKSYICYEIRVYALSGDQGGCSSILGNSKHKAPLSGPHINAITEEKGSILISWNSIPVQEQMGCLLHYRIYWKERDSNSQPQLCEIPYRVSQNSHPINSLQPRVTYVLWMTALTAAGESSHGNEREFCLQGKANWMAFVAPSICIAIIMVGIFSTHYFQQKVFVLLAALRPQWCSREIPDPANSTCAKKYPIAEEKTQLPLDRLLIDWPTPEDPEPLVISEVLHQVTPVFRHPPCSNWPQREKGIQGHQASEKDMMHSASSPPPPRALQAESRQLVDLYKVLESRGSDPKPENPACPWTVLPAGDLPTHDGYLPSNIDDLPSHEAPLADSLEELEPQHISLSVFPSSSLHPLTFSCGDKLTLDQLKMRCDSLML---", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:*.* ****::*:: ******:**.** * ***:*: ** ***:.**:***:*:*** **. *:*** ** :::: * .** ***.*.** ******* * **:: : :**.** ****** **.:**:*:**:*****:*: *: *:* * *****:**:*:* *:** . *. **:****:*: .**.* .:*** *.**.**** ******** *********:* :** ** ** *.*** *:**:***:* ** *****.*:***::** **:*************** ****:******::******.* **:****:.** .*********.*. ****************:* *: ** * ** ** ****** *:.:********:* **:***::** :*:***:****:* .****:****** * *.::**:**** *: *. :.. :*** * *:******:**.********:*** .******* *:*.**.*:*****.****:* ::***. **. ** **:**********.*.:**:**** ** *******.****:*********:******.:******* ****** :** .******* ** ** :**:**.*.**::*:*** .* ******** .***** *** * * *.**: *.:**:****:* ***::: ** *:* :* :*:**:.:*::* :: *. * .. :* **:****:***** **..*.* * :.* ** *.. **:*:*******:**..**. :**:: *: ******:*.****:** * *::****:*** :. ", "identical_positions": 544, "similar_positions": 186, "identity": "61.75%" }, { "cls_id": "homologset.agr.MGI:1270862", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O70240-1", "uniprot_id": "AXIN2_RAT", "id": "O70240-1", "name": "Axin-2", "aln": "MSSAVLVTLLPDPSSSFREDAPRPPVPGEEGETPPCQPS-VGKVQSTKPMP------VSSNARRNEDGLGEPEGRASPDSPLTRWTKSLHSLLGDQDGAYLFRTFLEREK--CVDTLDFWFACNGFRQMNLKDTKTLRVAKAIYKRYIENNSVVSKQLKPATKTYIRDGIKKQQIGSVMFDQAQTEIQAVMEENAYQVFLTSDIYLEYVRSGGENTAYMSNGGLGSLKVLCGYLPTLNEEEEWTCADLKCKLSPTVVGLSSKTLRATASVRSTETAENGFRSFKRSEPVNPYHVGSGYVFAPATSANDSELSSDALTDDSMSMTDSSVDGIPPYRMGSKKQLQREMHRSVKANGQVSLPHFPRTHRLPKEMTPVEPAAFAAELISRLEKLKLELESRHSLEERLQQIREDEEKEGSEQALSSRDGAPVQHPLALLPSGSYEEDPQTILDDHLSRVLKTPGCQSPGVGRYSPRSRSPDHH--HHHHQQCHALLPTGGKLPPEAA----CPLLGGKSFLTKQTTKHVHHHYIHHHAVPKTKEEIEAEATQRVRCLCPGGTDYYCYSKCKSHSKPPEPLPG-EQFCGSRGGTLPKRNTKGTEPGLALPAREGGMSSAAGAPQLPGEEGDRSQDVWQWMLESERQSKSKPHSTQSIRKSYPLESARAPPGERVSRHHLLG-ASGHPRSAARAHPFTQDPAMPPLTPPNTLAQLEEACRRLAEVSKPQKQRCCVASQQRDRNHPATGQAGPTSFSNPSLASEDHKEPKRLASVHALQASELIVTYFFCGEEIPYRRMLKAQSLTLGHFKEQLSKKGNYRYYFKKASDEFACGAVFEEIWDDETVLPMYEGRILGKVERID", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88566-1", "uniprot_id": "AXIN2_MOUSE", "id": "O88566-1", "name": "Axin-2", "aln": "MSSAVLVTLLPDPSSSFREDAPRPPVPGEEGETPPCQPS-VGKVQSTKPMP------VSSNARRNEDGLGEPEGRASPDSPLTRWTKSLHSLLGDQDGAYLFRTFLEREK--CVDTLDFWFACNGFRQMNLKDTKTLRVAKAIYKRYIENNSVVSKQLKPATKTYIRDGIKKQQIGSVMFDQAQTEIQAVMEENAYQVFLTSDIYLEYVRSGGENTAYMSNGGLGSLKVLCGYLPTLNEEEEWTCADLKCKLSPTVVGLSSKTLRATASVRSTETAENGFRSFKRSDPVNPYHVGSGYVFAPATSANDSELSSDALTDDSMSMTDSSVDGVPPYRMGSKKQLQREMHRSVKANGQVSLPHFPRTHRLPKEMTPVEPAAFAAELISRLEKLKLELESRHSLEERLQQIREDEEKEGSEQALSSRDGAPVQHPLALLPSGSYEEDPQTILDDHLSRVLKTPGCQSPGVGRYSPRSRSPDHHHQHHHHQQCHTLLPTGGKLPPVAA----CPLLGGKSFLTKQTTKHVHHHYIHHHAVPKTKEEIEAEATQRVRCLCPGGTDYYCYSKCKSHPKAPEPLPG-EQFCGSRGGTLPKRNAKGTEPGLALSARDGGMSSAAGAPQLPGEEGDRSQDVWQWMLESERQSKSKPHSAQSIRKSYPLESACAAPGERVSRHHLLG-ASGHSRSVARAHPFTQDPAMPPLTPPNTLAQLEEACRRLAEVSKPQKQRCCVASQQRDRNHSAAGQAGASPFANPSLAPEDHKEPKKLASVHALQASELVVTYFFCGEEIPYRRMLKAQSLTLGHFKEQLSKKGNYRYYFKKASDEFACGAVFEEIWDDETVLPMYEGRILGKVERID", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y2T1-1", "uniprot_id": "AXIN2_HUMAN", "id": "Q9Y2T1-1", "name": "Axin-2", "aln": "MSSAMLVTCLPDPSSSFREDAPRPPVPGEEGETPPCQPG-VGKGQVTKPMP------VSSNTRRNEDGLGEPEGRASPDSPLTRWTKSLHSLLGDQDGAYLFRTFLEREK--CVDTLDFWFACNGFRQMNLKDTKTLRVAKAIYKRYIENNSIVSKQLKPATKTYIRDGIKKQQIDSIMFDQAQTEIQSVMEENAYQMFLTSDIYLEYVRSGGENTAYMSNGGLGSLKVVCGYLPTLNEEEEWTCADFKCKLSPTVVGLSSKTLRATASVRSTETVDSGYRSFKRSDPVNPYHIGSGYVFAPATSANDSEISSDALTDDSMSMTDSSVDGIPPYRVGSKKQLQREMHRSVKANGQVSLPHFPRTHRLPKEMTPVEPATFAAELISRLEKLKLELESRHSLEERLQQIREDEEREGSELTLNSREGAPTQHPLSLLPSGSYEEDPQTILDDHLSRVLKTPGCQSPGVGRYSPRSRSPDHH--HHHHSQYHSLLPPGGKLPPAAASPGACPLLGGKGFVTKQTTKHVHHHYIHHHAVPKTKEEIEAEATQRVHCFCPGGSEYYCYSKCKSHSKAPETMPS-EQFGGSRGSTLPKRNGKGTEPGLALPAREGGAPGGAGALQLPREEGDRSQDVWQWMLESERQSKPKPHSAQSTKKAYPLESARSSPGERASRHHLWGGNSGHPRTTPRAHLFTQDPAMPPLTPPNTLAQLEEACRRLAEVSKPPKQRCCVASQQRDRNHSATVQTGATPFSNPSLAPEDHKEPKKLAGVHALQASELVVTYFFCGEEIPYRRMLKAQSLTLGHFKEQLSKKGNYRYYFKKASDEFACGAVFEEIWEDETVLPMYEGRILGKVERID", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P57095-1", "uniprot_id": "AXIN2_DANRE", "id": "P57095-1", "name": "Axin-2", "aln": "----MNRTLTDPMVSSFREDDPRPPVPGEEGETTCHHPSKLAMMRPKDPVKTIMADLRCSTARRDEDGLGEPEGSASPDSPLARWTKSLHFLLGDQDGAQLFRAYLEREK--CVDTLDFWFACNGFRQMDLKDTKTHRVAKAIYKRYIENNSIVAKQLKPATKTFIRDNIKRQQIDSAMFDQAQMEIQTAMEENAYQMFLTSDIYLEYVRTGCENPSHVNPNGLGGLKLVCGYLPTLNEEEEWSCNDFKAKALATVVGLSAKTLRSPP-LRAVEALEKGYRSYRRSDPGNPNRFTSGYSFAPATSANDSEVSSDALTDDSMSMTDSSVDAIPPYKLGSKKQLQREMQRNMRMNGQVSLPPFPRTRRPPKEMTPVEPAAFAAQLIARLERLKREQETMSSLEERLQQIQEEEERDESEMSSSS-----ASHSLPLLPPGTCEEDPQAILDEHLSRVLKTPGCQSPGLLRHSPRSRSPEQR-----------PLPRGG-LSTRSQSSSMNGYVPAKTFISRQSTKHIHHHYIHHHAGPKSKEQIEVEATQRVQCLCHGTSECCTAPYIRSRSLGRDQCASPAEVALGHSSTLSKRLCKSGEE-VNMEGLEN------SLLQLPADSTDRSQNVWQWILESDRQTKHKPHSTQNVKKSHSLEPTR-------THTWGGGGSSGHLRAHQPAHPFVQDPAMPPLPPPNTLAQLEEARRRLEEVSKPSKQRHSTSSLQRDKSHPVPVQNGSSAFP-----MDERKDPKKMSGCHSSLGSETVVTYFFCGEEIPYRRMMKTHSLTLGHFKEQLRKKGNYRYFFKRASDEFECGAVFEEVWDDCTVLPMYEGKILGKVDRMD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V407-1", "uniprot_id": "AXN_DROME", "id": "Q9V407-1", "name": "Axin", "aln": "---MSGHPSGIRKHDDNECSGPRPPVPGEE-----------------------------SRVKKMTEGVADTSKNSSP--SYLNWARTLNHLLEDRDGVELFKKYVEEEAPAYNDHLNFYFACEGLKQQTDPE-KIKQIIGAIYRFLRKSQLSISDDLRAQIKAIKTN--PEIPLSPHIFDPMQRHVEVTIRDNIYPTFLCSEMYILYIQQMSAQQERCTSSGATGSGSAG------SSGSGGSSLAGACALPPTTASGKQQLPQLVPPGAFINLPVS-----SVSGPPAGTCSASGSVYGPSTSASSS---GSISATDTLPRSST----LPTLHEDSVLSLCDDFEKVQMQEGGGSLGSGS-----------VGAGARAPDYPIRLTRDLLIATQKRRLEIRPPGAHGYVYNPSTTNTSYVPNSRVDSERASVSSGGRTDSDTMSISSCSMDGRPYIQRRHSSTESKAIRQSAMANKET------NTFQVIPRTQRLHSNEHR--------------PLKEEELVSLLIPKLEEVKRKRDLEERARERNPGAALLTNERSSASDRAFAEAIREKFALDEDNDQDILDQHVSRVWKDQTPHRSPGTMSPCPPIPSRRRTATHDSGMVSDGAMSLSGHSMKHSKSMPDHSSCSRKLTNKWPSMN---------------TDSGISMFSADTVTKYKDASSRSGSSTASKLEEAKRRLEDEPRRSR-RYAQPPMQHLSQQPLASFSSSSSGGSISLPHQPPPLPAKPP--------ETIVVFSFCEEPVPYRIKIPGTQPTLRQFKDYLPRRGHFRFFFKTHCEDPDSPVIQEEIVNDSDILPLFGDKAMGLVKPSD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .. . . ********* * .:: :*:.:.. :** . .*:::*: ** *:**. **: ::*.* * *:*:***:*::* : * :: ***: :.: ::.:*:. *: : . :.. :** * .:: .:.:* * ** *::*: *:: : . .* . .. . :. . .*... . : : . : . * * ** :.*:***..* .. : *::. :.: :*. : .* .* ::.: :* ** . * ..: *.: ** : ** * : . : : .. .: . * :.*. :* . :. :*. : :* .::. :* * . . :.: * : * *.::* .* :* . .: . : . : . . .* *. . . :. *:.. . .* :::* *. :. :* .: :. : *. ..: .. . ..* ::**** *** : .: : * . .. *: .:. . ..:. : * : . * :*.: ** * :*** : . ** :**: * ::*::*::** .:: . .: **: :* :**:: .: :* *. *", "identical_positions": 130, "similar_positions": 242, "identity": "15.2%" }, { "cls_id": "homologset.agr.MGI:1270863", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O70196-1", "uniprot_id": "PPCE_RAT", "id": "O70196-1", "name": "Prolyl endopeptidase", "aln": "--------------------------------------------MLSFQYPDVYRDETSVQDYHGHKICDPYAWLEDPDSEQTKAFVEAQNKITVPFLEQCPIRGLYKERMTELYDYPKYSCHFKKGKRYFYFYNTGLQNQRVLYVQDSL--EGEARVFLDPNTLSDDGTVALRGYAFSEDGEYFAYGLSASGSDWVTIKFMKVDGAKELPDVLERVKFTCMAWTHDGKGMFYNSYPQQDGKSDGTETSTNLHQKLCYHVLGTDQSEDVLCAEFPDEPKWMGGAELSDDGRYVLLSIWEGCDPVNRLWYCDLQQGSNGINGILKWVKLIDNFEGEYDYITNEGTVFTFKTNRNSPNYRLINIDFTDPDESKWKVLVPEHEKDVLEWVACVRSNFLVLCYLRNVKNILQLHDLTTGALLKTFPLDVGSVVGYSGRKKDSEIFYQFTSFLSPGVIYHCDLTREELEPRVFREVTV--KGIDASDYQTIQVFYPSKDGTKIPMFIVHKKGIKLDGSHPAFLYGYGGFNISITPNYSVSRLIFVRHMGGVLAVANIRGGGEYGETWHKGGILANKQNCFDDFQCAAEYLIKEGYTTSKRLTINGGSNGGLLVAACANQRPDLFGCVIAQVGVMDMLKFHKFTIGHAWTTDYGCSDSKQHFEWLLKYSPLHNVKLPEADDIQYPSMLLLTADHDDRVVPLHSLKFIATLQYIVGRSRKQSNPLLIHVDTKAGHGPGKPTAKVIEEVSDMFAFIARCLNIEWIQ-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QUR6-1", "uniprot_id": "PPCE_MOUSE", "id": "Q9QUR6-1", "name": "Prolyl endopeptidase", "aln": "--------------------------------------------MLSFQYPDVYRDETSVQEYHGHKICDPYSWLEDPDSEQTKAFVEAQNKITVPFLEQCPIRGLYKERMTELYDYPKYSCHFKKGKRYFYFYNTGLQNQRVLYVQDSL--EGEARVFLDPNTLSDDGTVALRGYAFSEDGEYFAYGLSASGSDWVTIKFMKVDGAKELPDVLERVKFTCMAWTHDGKGMFYNSYPQQDGKSDGTETSTNLHQKLCYHVLGTDQSEDILCAEFPDEPKWMGGAELSDDGRYVLLSIWEGCDPVNRLWYCDLQQEPNGITGILKWVKLIDNFEGEYDYVTNEGTVFTFKTNRNSPNYRLINIDFTDPDESKWKVLVPEHEKDVLEWVACVRSNFLVLCYLHDVKNILQLHDLTTGALLKTFPLDVGSVVGYSGRKKDSEIFYQFTSFLSPGVIYHCDLTKEELEPMVFREVTV--KGIDAADYQTIQIFYPSKDGTKIPMFIVHKKGIKLDGSHPAFLYGYGGFNISITPNYSVSRLIFVRHMGGVLAVANIRGGGEYGETWHKGGILANKQNCFDDFQCAAEYLIKEGYTSPKRLTINGGSNGGLLVAACANQRPDLFGCVIAQVGVMDMLKFHKFTIGHAWTTDYGCSDTKQHFEWLLKYSPLHNVKLPEADDIQYPSMLLLTADHDDRVVPLHSLKFIATLQYIVGRSRKQSNPLLIHVDTKAGHGAGKPTAKVIEEVSDMFAFIARCLNIEWIQ-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P48147-1", "uniprot_id": "PPCE_HUMAN", "id": "P48147-1", "name": "Prolyl endopeptidase", "aln": "--------------------------------------------MLSLQYPDVYRDETAVQDYHGHKICDPYAWLEDPDSEQTKAFVEAQNKITVPFLEQCPIRGLYKERMTELYDYPKYSCHFKKGKRYFYFYNTGLQNQRVLYVQDSL--EGEARVFLDPNILSDDGTVALRGYAFSEDGEYFAYGLSASGSDWVTIKFMKVDGAKELPDVLERVKFSCMAWTHDGKGMFYNSYPQQDGKSDGTETSTNLHQKLYYHVLGTDQSEDILCAEFPDEPKWMGGAELSDDGRYVLLSIREGCDPVNRLWYCDLQQESSGIAGILKWVKLIDNFEGEYDYVTNEGTVFTFKTNRQSPNYRVINIDFRDPEESKWKVLVPEHEKDVLEWIACVRSNFLVLCYLHDVKNILQLHDLTTGALLKTFPLDVGSIVGYSGQKKDTEIFYQFTSFLSPGIIYHCDLTKEELEPRVFREVTV--KGIDASDYQTVQIFYPSKDGTKIPMFIVHKKGIKLDGSHPAFLYGYGGFNISITPNYSVSRLIFVRHMGGILAVANIRGGGEYGETWHKGGILANKQNCFDDFQCAAEYLIKEGYTSPKRLTINGGSNGGLLVAACANQRPDLFGCVIAQVGVMDMLKFHKYTIGHAWTTDYGCSDSKQHFEWLVKYSPLHNVKLPEADDIQYPSMLLLTADHDDRVVPLHSLKFIATLQYIVGRSRKQSNPLLIHVDTKAGHGAGKPTAKVIEEVSDMFAFIARCLNVDWIP-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VKW5-1", "uniprot_id": "Q9VKW5_DROME", "id": "Q9VKW5-1", "name": "Prolyl endopeptidase", "aln": "MHTIFRGPLLYRRICQIVVPKTLPRNYIHRELPSNLTRAMPSTLSAKLAYPVARKDESVAEDFHGTQIKDVYRWLEDPDSTETEEFVNAQNSISRPFLENGEEWKKLNTKLTKLWNYPKYGCPMRYGNYYYYFMNTGLQNQSVMYQQKSLGDESESKVFLDPNTLSEDGTIALTQKAFSEDGKYMAYGLSESGSDWIKILIRDAETGKDLSEVLEKVKFSEISWTKDNKGFFYGRYPDQDGKTDGSETKQNENQKLYYHRVGESQDKDTLVVEFPEEPSWRIQSTVSDCGKYLILAIVKDCR-DNIVFYADLTPGAE-ITSKLNVKKIVEKFEADYDYITNEGSKIFFRTNKNAPNYQVIAIDFNNSAEDKWETLIAEHKSDVLDWVKCVDNDKLLVCYIRDVKSVLQVNSLKDGTLLREFDLDIGTIVGTSGEKKYSEIFYNFSSFLNPGSIYRYDFKTPDKSPSVFREIKLNLEGFRREDYAVEQIFYKSKDGTKVPMFIIRKKRDSVE-PRPCLLYGYGGFNISMLPSFGLSGLMFIDTFDGVLAYPNLRGGGEYGEKWHNGGRLLNKQNVFDDFQAAAEYLIENKYTTKDRLAIQGGSNGGLLVGSCINQRPDLFGAAVAQVGVMDMLRFHKFTIGHAWCSDYGNPSEKEHFDNLYKFSPLHNVHTPKGAETEYPSTLILTADHDDRVSPLHSLKFIAALQEAVRDSEFQKNPVLLRVYQKAGHGAGKPTSKRIEEATDILTFLSKSLNVDIVNV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V9P5-1", "uniprot_id": "Q9V9P5_DROME", "id": "Q9V9P5-1", "name": "Prolyl endopeptidase", "aln": "----------------------MSRSDALVQSPTDLSRSV-EEASLRIVYPEARKDGRFEEMIHGYKIKDVYRWLEDPDSVDTQQFVNAQNNISQSFLERSAERENINSKLTKLWNFPKYGCPMRHGNYYYFFKNTGLQNQSVLMQQKTL--ESPESIFLDTNSISSDGTTAISHIKFSEDGAFMAYGLSESGSDWNKIRIRNTKEGIDLPEILEKVKFSNVSWTKDSKGFFYGRYTDQDGIFDGSETKLAENQKLYYHLLGESPHQDILIAEFPEHPSWRFKTDISDCGKYLILSISHTVR-DNMLYYAELGSEEK-NAFQLELKPIVDKFEADFDYITNEGSNLYFHTNKDAPNYRVIVIDVNNPAEEHWTTPIPEHKKDVLEWAKCVDGNKLVVCYNCDVKHILQARDLSTGKLIRQFGLDIGSINGISGKKSNSEIFYGFSSFLSPGIIFYYDFAKPSEKPTVLREISLNLEGFSRDNYSVEQVFYKSTDDTDIPMFIVQRKRDIAE-PRPCLLYGYGGFNYSLMPSFGILSLMFMDTFDGVLAFPNLRGGGEYGMEWHNGGRMLSKQNVFNDFQAAAEFLTKNNYTTKDRLAIQGASNGGLLVGACINQRPDLFGAAVAQVGVMDMLRFHKFTIGHAWCSDYGNPDEKVHFANLIKFSPLHNVHIPLNPNQEYPSTLILTADHDDRVSPLHSYKFVAALQEAVRYSEYQLNPILLRVYTKAGHGAGKPTKMRISEATDIITFFKKTLNVDCINL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ** . :* : ** :* * * ******* :*: **:***.*: .***. : ::*:*:::***.* :: *: *::* ******* *: *.:* *. :***.* :*.*** *: ***** ::***** ***** .* : ... . :*.::**:***: ::**:*.**:**. *.:*** **:**. :*** ** :* . :* * .***:.*.* : :** *:*::*:* . * ::*.:* . *: ::::**.::**:****: : *:**:::***::* **. :. *.:* . :.**:.***:* ** .: *::** :** :** ..*. * *:: * **:*:: * **.*. :**** *:***.** *: *: . .* *:**:.: :*: :* . *:** *.*.*.:****:::* : .:*.:******** *: *.:.: *:*: :.*:** .*:******* **:** : .*** *:***.***:* :: **: .**:*:*.*******.:* ********..:*********:***:****** :*** .. * ** * *:******: * : :*** *:********* **** **:*:** * *. * **:*::* *****.**** *.*.:*:::*: : **:: : ", "identical_positions": 326, "similar_positions": 208, "identity": "42.95%" }, { "cls_id": "homologset.agr.MGI:1274781", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O55005-1", "uniprot_id": "ROBO1_RAT", "id": "O55005-1", "name": "Roundabout homolog 1", "aln": "---MKWKHLPLLVMISLLTLSKKH---------LLLAQLIPDPEDLERGNDNGTPA-----------PTSDNDDNSLGYTGSRLRQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKSRPDEGVYICVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDER--------ITIRGGKLMITYTRKSDAGKYVCVGTNMVGERESKVADVTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTFGWRKDD--GELPKSRYEIRDD-HTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQEPPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTG--DLTVTNVQRSDVG-YYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTLTLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLESG--VLQIRYAKLGDTGRYTCTASTPSGEATWSAYIEVQEFGVP-VQPPRPTDPNLIPSAPSKPEVTDVSKNTVTLLWQPNL--NSG-ATPTSYIIEAFSHASGSSWQTVAENVKTETFAIKGLKPNAIYLFLVRAANAYGISDPSQISDPVKTQD--------VPPTTQGVDHKQVQRELGN-VVLHLHNPTILSSSSVEVHWT--VDQQSQYIQGYKILYRPSGASHGE------------------------------------------------------------SEWLVFEVRTPTKNSVVIPDLRKGVNYEIKARPFFNEFQGADSEIKFAKTLEERPSAPPRSVTVSKNDGNGTAILVTWQPP-PEDTQNGMVQEYKVWCLGNE-----TRYHINKTVDGSTFSVVIPFLVPGIRYSVEVAASTGAGPGVKSEPQFIQLDSHGNPVSP--EDQVSLAQQIS--DVVKQPAFIAGIGAACWIILMVFSIWLYRHRKKRNGLSSTYAGIR--KVPSFTFTPTVTYQRGGEAVSSGGRPGLLNISEPATQPWLADTWPNTGNSHNDCSINCCTASNGNSDSNLTTYSRPADCIANYNNQLDNKQTNLMLPESTVYGDVDLSNKINEMKTFNSPNLKDGRFVNPS---GQPTPYATTQLIQANLINN-MNNGGGDSS--------EKHWKP----PGQQKQEVAPIQYNIMEQNKLNKD-YRANDTILPTIPYNHSYDQNTGGSYNSSDRGSSTSGSQGHKKGARTPKAPKQGGMNWADLLPPPPAHPPPHSNSEEYSMSVDESYDQEMPCPVPPARMYLQQDELEEEEA----ERGPTPPVRGAASSPAAVSYSHQSTATLTPSPQEELQPMLQDCPEDLGHMPHPPDRRRQPVSPPPPPRPISPPHTYGYISGPLVSDMD----TDAPEEEEDEADMEVAKMQTR-------------RLLLRGLEQTPASSVGDLESSVTGSMINGWGSASEEDNISSGRS-SVSSSDGSFFTDADFAQAVAAAAEYAGLKVARRQMQ-------DAAGRRHFHASQCPRPTSPVSTDSNMSAAVIQKARPTKKQKHQP----GHLRREAYTDDLPPPPVPPPAIK-SPSVQSKAQLEA-RPIMGPKLASIEARADRSSDRKGGSYKGREALDGRQVTDLRTSPGDPREAQEQPNEGKARGTKTAKRDLPPAKTHLIPEDILPYCRPTFPTSNNPR---DPSSSSSMSSRGSGSRQREQANVGRRNMAEMQVLGGFERGDENNEELEETES", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O89026-1", "uniprot_id": "ROBO1_MOUSE", "id": "O89026-1", "name": "Roundabout homolog 1", "aln": "-----------------MIAEPAH---------FYLFGLIC------------------------------------LCSGSRLRQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKSRPDEGVYICVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDER--------ITIRGGKLMITYTRKSDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDD--GELPKSRYEIRDD-HTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQEPPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTG--DLTITNVQRSDVG-YYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTLILSCVATGSPAPTILWRKDGVLVSTQDSRIKQLESG--VLQIRYAKLGDTGRYTCTASTPSGEATWSAYIEVQEFGVP-VQPPRPTDPNLIPSAPSKPEVTDVSKNTVTLSWQPNL--NSG-ATPTSYIIEAFSHASGSSWQTAAENVKTETFAIKGLKPNAIYLFLVRAANAYGISDPSQISDPVKTQD--------VPPTSQGVDHKQVQRELGN-VVLHLHNPTILSSSSVEVHWT--VDQQSQYIQGYKILYRPSGASHGE------------------------------------------------------------SEWLVFEVRTPTKNSVVIPDLRKGVNYEIKARPFFNEFQGADSEIKFAKTLEEAPSAPPRSVTVSKNDGNGTAILVTWQPP-PEDTQNGMVQEYKVWCLGNE-----TKYHINKTVDGSTFSVVIPSLVPGIRYSVEVAASTGAGPGVKSEPQFIQLDSHGNPVSP--EDQVSLAQQIS--DVVRQPAFIAGIGAACWIILMVFSIWLYRHRKKRNGLTSTYAGIR--KVPSFTFTPTVTYQRGGEAVSSGGRPGLLNISEPATQPWLADTWPNTGNNHNDCSINCCTAGNGNSDSNLTTYSRPADCIANYNNQLDNKQTNLMLPESTVYGDVDLSNKINEMKTFNSPNLKDGRFVNPS---GQPTPYATTQLIQANLSNN-MNNGAGDSS--------EKHWKP----PGQQKPEVAPIQYNIMEQNKLNKD-YRANDTIPPTIPYNQSYDQNTGGSYNSSDRGSSTSGSQGHKKGARTPKAPKQGGMNWADLLPPPPAHPPPHSNSEEYNMSVDESYDQEMPCPVPPAPMYLQQDELQEEED----ERGPTPPVRGAASSPAAVSYSHQSTATLTPSPQEELQPMLQDCPEDLGHMPHPPDRRRQPVSPPPPPRPISPPHTYGYISGPLVSDMD----TDAPEEEEDEADMEVAKMQTR-------------RLLLRGLEQTPASSVGDLESSVTGSMINGWGSASEEDNISSGRS-SVSSSDGSFFTDADFAQAVAAAAEYAGLKVARRQMQ-------DAAGRRHFHASQCPRPTSPVSTDSNMSAVVIQKARPAKKQKHQP----GHLRREAYADDLPPPPVPPPAIK-SPTVQSKAQLEV-RPVMVPKLASIEARTDRSSDRKGGSYKGREALDGRQVTDLRTNPSDPREAQEQPNDGKGRGTRQPKRDLPPAKTHLGQEDILPYCRPTFPTSNNPR---DPSSSSSMSSRGSGSRQREQANVGRRNMAEMQVLGGFERGDENNEELEETES", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y6N7-1", "uniprot_id": "ROBO1_HUMAN", "id": "Q9Y6N7-1", "name": "Roundabout homolog 1", "aln": "---MKWKHVPFLVMISLLSLSPNH---------LFLAQLIPDPEDVERGNDHGTPI-----------PTSDNDDNSLGYTGSRLRQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDER--------ITIRGGKLMITYTRKSDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDD--GELPKSRYEIRDD-HTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQEPPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTG--DLTITNVQRSDVG-YYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENG--VLQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVP-VQPPRPTDPNLIPSAPSKPEVTDVSRNTVTLSWQPNL--NSG-ATPTSYIIEAFSHASGSSWQTVAENVKTETSAIKGLKPNAIYLFLVRAANAYGISDPSQISDPVKTQD--------VLPTSQGVDHKQVQRELGN-AVLHLHNPTVLSSSSIEVHWT--VDQQSQYIQGYKILYRPSGANHGE------------------------------------------------------------SDWLVFEVRTPAKNSVVIPDLRKGVNYEIKARPFFNEFQGADSEIKFAKTLEEAPSAPPQGVTVSKNDGNGTAILVSWQPP-PEDTQNGMVQEYKVWCLGNE-----TRYHINKTVDGSTFSVVIPFLVPGIRYSVEVAASTGAGSGVKSEPQFIQLDAHGNPVSP--EDQVSLAQQIS--DVVKQPAFIAGIGAACWIILMVFSIWLYRHRKKRNGLTSTYAGIR--KVPSFTFTPTVTYQRGGEAVSSGGRPGLLNISEPAAQPWLADTWPNTGNNHNDCSISCCTAGNGNSDSNLTTYSRPADCIANYNNQLDNKQTNLMLPESTVYGDVDLSNKINEMKTFNSPNLKDGRFVNPS---GQPTPYATTQLIQSNLSNN-MNNGSGDSG--------EKHWKP----LGQQKQEVAPVQYNIVEQNKLNKD-YRANDTVPPTIPYNQSYDQNTGGSYNSSDRGSSTSGSQGHKKGARTPKVPKQGGMNWADLLPPPPAHPPPHSNSEEYNISVDESYDQEMPCPVPPARMYLQQDELEEEED----ERGPTPPVRGAASSPAAVSYSHQSTATLTPSPQEELQPMLQDCPEETGHMQHQPDRRRQPVSPPPPPRPISPPHTYGYISGPLVSDMD----TDAPEEEEDEADMEVAKMQTR-------------RLLLRGLEQTPASSVGDLESSVTGSMINGWGSASEEDNISSGRS-SVSSSDGSFFTDADFAQAVAAAAEYAGLKVARRQMQ-------DAAGRRHFHASQCPRPTSPVSTDSNMSAAVMQKTRPAKKLKHQP----GHLRRETYTDDLPPPPVPPPAIK-SPTAQSKTQLEV-RPVVVPKLPSMDARTDRSSDRKGSSYKGREVLDGRQVVDMRTNPGDPREAQEQQNDGKGRGNKAAKRDLPPAKTHLIQEDILPYCRPTFPTSNNPR---DPSSSSSMSSRGSGSRQREQANVGRRNIAEMQVLGGYERGEDNNEELEETES", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32T813-1", "uniprot_id": "A0AB32T813_DANRE", "id": "A0AB32T813-1", "name": "", "aln": "---MEFIPLVVSILAMLVMMGVQHGGTPG---VPRHASLRNQPNQWCKRPHGSFLVGAHHRPTQQRHHNSKKHKCFQDFQRSRLRQEDYAPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTVEWYKDGERVETDRDNPRSHRMLLPTGSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSHNASLEVAILRDDFRQNPVDVMVAAGEPAVMECQPPRGHPEPTISWKKDGVNIDDRDER--------ITIRGGKLMITNTRKTDAGKYVCVGTNMMGERESEIAELTVLERPSFLRKPSSQSVLVDQSVEFRCEAQGDPVPTIRWRKED--GELPKGRYEIWED-HTLKLKRLTSGDAGTYTCQAENMMGKTEASATLTVHVPPVFVVRPRNQVAGMGRTVTFQCEATGSPQPAIFWQKEGSQNLLFSSQPPPPSSRFSVSQTG--DLTITAVERSDGG-YYSCQALNIAGSVITKALLEVTDVISDRPPPIVRQGPTNQTVAVDGTVVLSCQATGTPIPTILWRKDGVLVSTHDSRLKQLDTG--ALQIRYAKLGDTGMYTCTASTPSGEASWKAYLEVQEFGAP-VQPGRPTDPNLIPSAPSKPDVTDVSRTSVSLSWKPNL--NAG-ATPTSYVIEAFSHAAGSSWQTLADHVKTESFVLKGLKPSAVYLFLVRAANAYGLSDPSPISDAVKTQD--------VPPTSQGVEHGQIQRELGD-VVIHLHNPTILSSSSVRVQWT--VEQQSQYIQGYKVMYRPSPEGAPQR-----------------------------------------------------------VDWAMFEVGAPGEHSAVVTQLKKGITYEFKVRPFFNEFQGTDSDIKVGKTLEEAPSAAPRGVTVTGSGDNGTAVLVAWQPP-PEEEQNGVVQEYKIWCLGNE-----SRYHINRTVDGSTHSVLIPGLVAGVTYRLEVAAGTGAGPGVKSDPTSFQLDSSGRVLPPPLDDDNTISQQIS--DVVRQPAFIAGIGAACWIILMVFSIWLYRHRKKRNGLSSSYAGIR--KVPSFTFTPTVAYQRGGEAVSSAGRPGLLNIGEPATQPWLADTWPNSCSNHNDCTINCCTGSNGNSDSNLATYSRPADCIANYSNQMDNKATNLLAPDTGLYSDVDLSNKINEMKTFNSPNLKDGRFMGPG---GQPTPYATTQLIQSSLANNNMNSSSGGSGGGSADFNEKQSWKSSQGTPQKQADINTPLQYNVMEQNKLNKDHYRGEGPISVTIPYNQAQDVLTGETYSSSDRGSSTSGSQGQKKGGRTTKQAKQNPMNWTELLPPPPVNPPP---CQEYTLVMDDSYDTDLQCPLPPSRMYLQPDELEEEEDEVELERGPTPPVRGAASSPAAVSYSHQSTATLTPSPQEEMHPMLQDNPD-------LHERRRLLVSPPPPPRPLSPPHTYGYISSPLGLDTDGLEEEDDDEEEGDETDAEVARVHQHHMMHPHQQHLPQQRALLRGLEQTPASSTCDLESSVTGSMINGWGSASEEDNASSGRSSAVSSSDGSFFTDADFAQAVAAAAEYAGLRVAKHPGKGHHQLPVSGAARKYQNLPAGHRPGSPVSTDSNVSAAPGQR-RPLKRQKQHPAAQTGYQRREAYTEDLPPPPIPPPAMLKSPTHPAKTIPEGPRGAMSPRSSSADGKDRRTGAG------GPRVRDG---SDTRTSSSERRDGQDVQR-GQRTGKNSKQDEAVKSRQHPGSEDILPYSRPSFPAVHSPRGERDPSSSSSLSSRGSGGRRRGEGPPGARRNPADIGLNTIGAFQTGGDELEMVES", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9PC46-1", "uniprot_id": "M9PC46_DROME", "id": "M9PC46-1", "name": "", "aln": "MHLCEMRGMPLRLQPQCLTNESEIQIKIKSKIKNKTASEIKRRHRNNRDFHGERLKIMPVDRSRRAVFPLLLLLAGLNGLTQVGALKGENPRIIEHPMDTTVPKNDPFTFNCQAEGNPTPTIQWFKDGRELKTDTG---SHRIMLPAGGLFFLKVIHSRR-ESDAGTYWCEAKNEFGVARSRNATLQVAFLRDEFRLEPANTRVAQGEVALMECGAPRGSPEPQISWRKNGQTLNLVGNKRI------RIVDGGNLAIQEARQSDDGRYQCVVKNVVGTRESATAFLKVHVRPFLIRGPQNQTAVVGSSVVFQCRIGGDPLPDVLWRRTASGGNMPLRRVHVLED-RSLKLDDVTLEDMGEYTCEADNAVGGITATGILTVHAPPKFVIRPKNQLVEIGDEVLFECQANGHPRPTLYWSVEGNSSLLLPGYR-DGRMEVTLTPEGRSVLSIARFAREDSGKVVTCNALNAVGSVSSRTVVSVDTQF-ELPPPIIEQGPVNQTLPVKSIVVLPCRTLGTPVPQVSWYLDGIPIDVQEHERRNLSDAGALTISDLQRHEDEGLYTCVASNRNGKSSWSGYLRLDTPTNPNIKFFRAPELSTYPGPPGKPQMVEKGENSVTLSWTRSN--KVGGSSLVGYVIEMFGKNETDGWVAVGTRVQNTTFTQTGLLPGVNYFFLIRAENSHGLSLPSPMSEPITVG---------TRYFNSGLDLSEARASLLSGDVVELSNASVVDSTSMKLTWQ--IIN-GKYVEGFYVYARQLPNPIVNNPAPVTSNTNPLLGSTSTSASASASASALISTKPNIAAAGKRDGETNQSGGGAPTPLNTKYRMLTILN-GGGASSCTITGLVQYTLYEFFIVPFYKSVEGKPSNSRIARTLEDVPSEAPYGMEALLLN--SSAVFLKWKAP-ELKDRHGVLLNYHVIVRGIDTAHNFSRILTNVTIDAASPTLVLANLTEGVMYTVGVAAGNNAGVGPYCVPATLRLDPITKRLDPFINQRYPINQDHVN-DVLTQPWFIILLGAILAVLMLSFGAMVFVKRKHMMMKQSALNTMRGNHTS-DVLKMPSLSARNGNGYWLDSSTGGMVWRPSPGGDSLEMQKDHIADYAPVCGAPGSPAGGGTSSG----GSGGAGSGASGGDDIHGGHGSERNQQRYVGEYSNIPTDYAEVSSFGKAPSEYGRHGN-----ASPAPYATSSILSP----------------------------------------------HQQQQQQQPRYQQRPVPGYGLQRPMHPHYQQQQHQQQQAQQTHQQHQALQQHQQ---LPPSNIYQQMSTTSEIYPTNTGPSRSVYSEQY-----------YYPKDKQRHIHITENKLSNCH------------------TYEAAPGAKQSSPISSQF------------------------------------------------------------------------------------------------ASVRRQQLPPNCSIGRESARFK----------VLNTDQGKNQ-QNLLDLDGSSMCYNGLADSGCGGSPSPMAMLMSHEDE----------------HALYHTADGDLDDMERLYVKVDEQQPPQQQQQLIP--------------------------------------------LVPQHPAEGHLQSWRNQS-----------------TRSSRKNGQECIKEPSELIYAPGSVASERSLLSNSGSGTSSQPAGHNVXPLLPGSSLG---QSQSKSQSQSQSQSDLQSQEQLYAREVRELLAWCERFNNGGVENFE------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VPZ7-1", "uniprot_id": "Q9VPZ7_DROME", "id": "Q9VPZ7-1", "name": "", "aln": "-------------------------------------------------------------MDLRFVFIVFLLKW-------THAQGSHPPRIVEHPIDTTVPRHEPATLNCKAEGSPTPTIQWYKDGVPLKILPG---SHRITLPAGGLFFLKVVNSRR-ETDAGIYWCEAKNELGVARSRNATLQVAVLRDEFRLEPQNTRIAQGDTALLECAAPRGIPEPTVTWKKGGQKLDLEGSKRV------RIVDGGNLAIQDARQTDEGQYQCIAKNPVGVRESSLATLKVHVKPYIIRGPHDQTVLEGASVTFPCRVGGDPMPDVLWLRTASGGNMPLDRVSVLED-RSLRLERVTIADEGEYSCEADNVVGAITAMGTLTVYAPPKFIQRPASKSVELGADTSFECRAIGNPKPTIFWTIKNNSTLIFPGAPPLDRFHSLNTEEGHSILTLTRFQRTDKDLVILCNAMNEVASITSRVQLSLDSQE-DRPPPIIISGPVNQTLPIKSLATLQCKAIGLPSPTISWYRDGIP--VQPSSKLNITTSGDLIISDLDRQQDQGLYTCVASSRAGKSTWSGFLRIELPTNPNIKFYRAPEQTKCPSAPGQPKILNATASALTIVWPTSD--KAGASSFLGYSVEMYCTNQSRTWIPIASRLSEPIFTVESLTQGAAYMFIVRAENSLGFSPPSPISEPITAGKLVGVRDGSESTGTSQLLLSDVETLLQANDVVELLEANASDSTTARLSWD--IDS-GQYIEGFYLYARELHS--------------------------------------------------------------SEYKMVTLLNKGQGLSSCTVPGLAKASTYEFFLVPFYKSIVGKPSNSRRMRTLEDVPEAPPYGMEAIQFN--RTSVFLKWLPPQPNRTRNGILTSYNVVVKGLD-VHNTTRIFKNMTIDAAAPTLLLANLTTGVTYYIAVAAATRVGVGPFSKPAVLRIDARTQSLDTGY-TRYPISRDIAD-DFLTQTWFIVLLGSIIAIIVFLLGALVLFKR-YQFIKQTSLGSLHGNHAIGTVRKFPTLPLNGGGAVGAGGSNSTAAAGQSGHGLWIDPTSG-VWRQAAGGGNPGGVGSCTTKEQ----LPGYAQATAQQGQQPTLLPDYERLSPLNMPDYAEVACSTFKSPTHGAPPMGGGGGGQSASLYDSCGAYATTNVVAN----------------------------------------------VKLYQN---RYATKPNQSSGSNNNNHQGNDYQSTGMYSAPPSAHYGCLEPKQQQ---QQQQPNLMTTSTASTAILTNS-------------------------PAKVKKINITENKMDQLEG----------------KSERTNPFNQQQQLLLASN------------------------------------------------------------------------------------------------ALKQGLGAYANTTLAAQMASGG----------GAGTLRRQRQPKTLYKSENNILGKSGLRQNTMNASVG-------------------------------APSNGQMDFLT--------GGPPSEGGDFSG--------------------------------------------LGLCNSTNQLLNDWASSA-----------------SIAAPGDYHFGSKQPSKQHLYVKAKDGTWSAVSSDAYQSFKHQQQH--HPFLAGSGDN---TKSLASVNSLAGDSKFLS-------------------SFGSSANV-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W213-1", "uniprot_id": "Q9W213_DROME", "id": "Q9W213-1", "name": "", "aln": "-----------------------------------MHPMHPENHAIARSTSTTNNPSRSRSSRMWLLPAWLLLVLVASNGLPAVRGQYQSPRIIEHPTDLVVKKNEPATLNCKVEGKPEPTIEWFKDGEPVSTNEK--KSHRVQFKDGALFFYRTMQGKK-EQDGGEYWCVAKNRVGQAVSRHASLQIAVLRDDFRVEPKDTRVAKGETALLECGPPKGIPEPTLIWIKDGVPLDDLKAMSFGASSRVRIVDGGNLLISNVEPIDEGNYKCIAQNLVGTRESSYAKLIVQVKPYFMKEPKDQVMLYGQTATFHCSVGGDPPPKVLWKKEE--GNIPVSRARILHDEKSLEISNITPTDEGTYVCEAHNNVGQISARASLIVHAPPNFTKRPSNKKVGLNGVVQLPCMASGNPPPSVFWTKEGVSTLMFPNSS---HGRQHVAADG--TLQITDVRQEDEG-YYVCSAFSVVDSSTVRVFLQVSSLD-ERPPPIIQIGPANQTLPKGSVATLPCRATGNPSPRIKWFHDGHAVQAGNRYSIIQGSS---LRVDDLQLSDSGTYTCTASGERGETSWAATLTVEKPGST--SLHRAADPSTYPAPPGTPKVLNVSRTSISLRWAKSQEKPGAVGPIIGYTVEYFSPDLQTGWIVAAQRVGDTQVTISGLTPGTSYVFLVRAENTQGISVPSGLSNTIKTIE--------ADFDAASANDLSAARTLLTGKSVELIDASAINASAVRLEWMLHVSADEKYVEGLRIHYKDASVPS--------------------------------------------------------------AQYHSITVMDASAESFVVGNLKKYTKYEFFLTPFFETIEGQPSNSKTALTYEDVPSAPPDNIQIGMYN--QTAGWVRWTPP-PSQHHNGNLYGYKIEVSAGN----TMKVLANMTLNATTTSVLLNNLTTGAVYSVRLNSFTKAGDGPYSKPISLFMDPTHHVHPPRAHPSGTHDGRHEGQDLTYHNNGNIPPGDINPTTHKKTTDYLSGPWLMVLVCIVLLVLVISAAISMVYFKRKHQMTKELGHLSVVSDNEITALNINSKESLWIDHHRGWRTADTD----------------------------KDSGLSESKLLSHVNSSQSNYNNSDGGTDYAEVDTRNLTTFYNCRKSPDN-----PTPYATTMIIGTS-----------------------------------------------------------SSETCTKTTSISADKDSGTHSPYSDAFAGQVPAVPVVKSN----YLQYPVEPINWSEFLPPPPEHPPP------------------------SSTYGYAQGSPESSRK----------------SSKSAGSGISTNQSILNAS------------------------------------------------------------------------------------------------IHSSSSGGFSAWGVSPQYAVACPPENVYSNPLSAVAGGTQNRYQITPTNQHPPQLPAYFATTGPGGAVPPNHLPFATQRH--------------AASEYQAGLNAARCAQSRACNSCDALATPSPMQPPPP---------------------------------------------VPVPEGWYQPVHPNSHP-----------------MHPTSSNHQIYQCSSECSDHSRSSQSHKRQLQLEEHGSSAKQRGGHHRRRAPVVQPCMESENENMLAEYEQRQYTSDCCNSSREGDTCSCSEGSCLYAEAGEPAPRQMTAKNT", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ***:*** * * : :* *:**:.** * **::*:*.* :. ***: : *.*** : ::.:: . * * * * *:* .* * *::*:*::*.***:** :* :. :* *: *::** .*:* *** : * *.* :: : **:* * .. * *.* *: * :* *** * : * :* ::: * . . :. * * *** * . * : *::* * : .* ::*.: :* * * * * *.* :* * . * * ** * :* .: . :. . : * * * * *:::* :. ..*::. . : * * :: . : * . *.::. . * :. :.: : ***:: **.***:. . * * : * * * : * ** . . : * * *** ** *:::* . : :: . . *..: . *..*. *.: : .:::: * . . .. .* :* : * . .: . .* .. *.*::** *: *:* ** :*:.:.. . * :.* :.. .::: .: * : :*::* : : : * .: * : **: **:: . * *: : * *: *. .* .: . :: : * .* ::* : *:: . : : * *::.:: :::: *. * * : : : . .* * . * : :*. . . . *. : * : : . . . . . : . : : . . .***: :: : . :.: . :. . .. .. . : : . . . : . : : : .: . * . : . . . .. : . : . ", "identical_positions": 194, "similar_positions": 295, "identity": "10.59%" }, { "cls_id": "homologset.agr.MGI:1274782", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q2KMM4-1", "uniprot_id": "LX12B_RAT", "id": "Q2KMM4-1", "name": "Arachidonate 12-lipoxygenase, 12R-type", "aln": "--------------MATYKVKVATGTDFFSGTLDSISLTIVGTQGESHKQRLNHFGRDFATGAVDDYTVQCQQDLGELIIIRLHKEPHSFLPKDPWYCNYVQICAP--NCRVYHFPAYQWMDGYE-TLSLREATGKTTADDTLPILLEHRQEEIRAKKDFYHWRVFVPGLPNYVDIPSYHPPPRRCRNPNRPEWNGYIPGFPILINIKATRFLNLNLRFSFVKTASFFYRLGPMALAFKLRGLVDRKRSWKRLKDIKNIFPAT--KTVVSEYVAEHWTEDSFFGYQYLNGINPGHIRRCMQIPDKFPVTDEMVAPFLGEGTCLQAELEKGNIYLADYRILDGIPTVELNGQKQHHCAPICLLHFGPDGNMMPIAIQLSQTPGPDCPIFLPNDSEWDWLLAKTWVRYAEFYSHEAVAHLLESHLIGEAFCLALLRNLPMCHPLYKLLIPHTRYNVQINSIGRALLLNKGGLSARAMSLGLEGFAQVMVRGLSELTYKSLCIPNDFVERGVQDLPGYYFRDDSLAVWYAMERYVTEIITYYYPNDAAVEGDPELQCWVQEIFKECLLERESSGFPTCLRTVPELIEYVTMVMYTCSARHAAVNTGQLEYTSWMPNFPSSMRNPPMQSKGLTTLQTFMDTLPDVKTTCIVLLVLWTLCREPDDRRPLGHFPDIHFVEEAPRRSMEAFRQNLNQISHNIRQRNKCLNLPYYYLDPVLIENSISI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70582-1", "uniprot_id": "LX12B_MOUSE", "id": "O70582-1", "name": "Arachidonate 12-lipoxygenase, 12R-type", "aln": "--------------MATYKVKVATGTDFFSGTLDSISLTIVGTQGESHKQRLNHFGRDFATGAVDDYTVQCQQDLGELIIIRLHKEPHSFLAKDPWYCNYVQICAP--DCRVYHFPAYQWMDGYE-TLALREATGKITADDTLPILLEHRQEEIRAKKDFYHWRVFVPGLPNYVDIPSYHPPPRRCRNPNRPEWDGYIPGFPILINIKATRFLNSNLRFSFVKTASFFYRLGPMALAFKLRGLVDRKRSWKRLKDIKNIFPAT--KSVVSEYVAEHWTEDSFFGYQYLNGINPGLIRRCTQIPDKFPVTDEMVAPFLGEGTCLQAELERGNIYLADYRILDGIPTVELNGQQQHHCAPMCLLHFGPDGNMMPIAIQLSQTPGPDCPIFLPNDSEWDWLLAKTWVRYAEFYSHEAVAHLLESHLIGEAFCLALLRNLPMCHPLYKLLIPHTRYNVQINSIGRALLLNKGGLSARAMSLGLEGFAQVMVRGLSELTYKSLCIPNDFVERGVQDLPGYYFRDDSLAVWYAMERYVTEIITYYYPNDAAVEGDPELQCWVQEIFKECLLGRESSGFPTCLRTIPELIEYVTMVMYTCSARHAAVNSGQLEYTSWMPNFPSSMRNPPMQTKGLTTLQTYMDTLPDVKTTCIVLLVLWTLCREPDDRRPLGHFPDIHFVEEGPRRSIEAFRQNLNQISHNIRQRNKCLTLPYYYLDPVLIENSISI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75342-1", "uniprot_id": "LX12B_HUMAN", "id": "O75342-1", "name": "Arachidonate 12-lipoxygenase, 12R-type", "aln": "--------------MATYKVRVATGTDLLSGTRDSISLTIVGTQGESHKQLLNHFGRDFATGAVGQYTVQCPQDLGELIIIRLHKERYAFFPKDPWYCNYVQICAP--NGRIYHFPAYQWMDGYE-TLALREATGKTTADDSLPVLLEHRKEEIRAKQDFYHWRVFLPGLPSYVHIPSYRPPVRRHRNPNRPEWNGYIPGFPILINFKATKFLNLNLRYSFLKTASFFVRLGPMALAFKVRGLLDCKHSWKRLKDIRKIFPGK--KSVVSEYVAEHWAEDTFFGYQYLNGVNPGLIRRCTRIPDKFPVTDDMVAPFLGEGTCLQAELEKGNIYLADYRIMEGIPTVELSGRKQHHCAPLCLLHFGPEGKMMPIAIQLSQTPGPDCPIFLPSDSEWDWLLAKTWVRYAEFYSHEAIAHLLETHLIAEAFCLALLRNLPMCHPLYKLLIPHTRYTVQINSIGRAVLLNEGGLSAKGMSLGVEGFAGVMVRALSELTYDSLYLPNDFVERGVQDLPGYYYRDDSLAVWNALEKYVTEIITYYYPSDAAVEGDPELQSWVQEIFKECLLGRESSGFPRCLRTVPELIRYVTIVIYTCSAKHAAVNTGQMEFTAWMPNFPASMRNPPIQTKGLTTLETFMDTLPDVKTTCITLLVLWTLSREPDDRRPLGHFPDIHFVEEAPRRSIEAFRQRLNQISHDIRQRNKCLPIPYYYLDPVLIENSISI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6YX78-1", "uniprot_id": "A0A8M6YX78_DANRE", "id": "A0A8M6YX78-1", "name": "", "aln": "MLNNRISILIFRAMDAVYEVEVTTGSMAHAGTFDNIFITLIGTEGESERNKLDTYGRDFNIGMKVTYKVTTRLSLGTLLLVRLEKDNFLFLPENDWFCSLVNIKTP--EKHVISFPCYRWMTKRE-VIELREAKATKIYEEQYPQLKEHRQNELKLNKEVYRWTVFKAGLP---QQAVFQDPLS-------------VP---------------SVVRFSFTKDIDSAFSRSTALREIKMKKLAKKADQWPAIKHMKRAFWPS--KTTISKYVYLHWKDDDFLGYQLLNGPNPLMLHRCSELPLNFAVSDDMLLPFLESGTSLNVEMKQGNIFLCDYKRLADLPTQVINGKQQFVTAPLCLLYKNQEGKLLPIAIQLQQEASEHSPVFLPSDSELDWLTAKLYVRNADCLEHQAALHLRS--LLAETFTLSLLRNLPTVHPIHKLLVPHIRYTLQMNSLVRHRLIGPDGVLSQCTSIGHEGMMALMRKALSDLTYSSLCLPEDISGRQLDSLPNFFYRDDGLRVWAFINDFVRSVVEFFYQNDSDVQKDTELQDWINDIFIHGFLEQSSSGIPQSFSTVEELIKFLTMMIFTVSAQHAALRAGQFDYGSWFPNTPGSLKSPPPACKGSSDKNTVLQALPDINTSANLASVFWLLSKPSADLVPLGQYPEDYFCQTAVQKMMRDFQAELAFFSEYVEDRNADLLVPYKYMTPENICNSVSV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1QKM3-1", "uniprot_id": "F1QKM3_DANRE", "id": "F1QKM3-1", "name": "", "aln": "--------------MGGFHVTVRTSAFPVSGTYSSVWISLIGSLCESPPIKVEHR---LLPGSACTVVIMPEEEVGILVLVKLRLEAKPGFPDLDWHCQDVQVKQSSEDPEMEVFPCNKWIRTADGHIILHNDKVCLKKEETLEVLTNHREKDLQCKQQIIKWGTFAEGSPHCIAMTSVADLGP---------------------------------NLSYIRKR-------PVTNVHYIKGFIERRTSWRSLQELETVFLFSGSENMIAKYVQAHWQEDAFFGYQCLNGCNPLCVRQIHHLPPNFSVTSEMLKSFLPEGSSLDQEMEKGRVYLLDYEVLDQLPANTVNGKQTYLSAPLCLLHYNQDEELKPIAIQLQQVPGPQNPIFLPSDAPPDWLLAKMWVRNSDFQIHQLLSHFFRTHLLGEVCCTATLRQLPEIHPLFQLLMPHIRSTLQINIQARATLLAANGVFDKSVACGLEAIPQLFTRATQRLRYSSLCVPDDVKERGLDALPVCYYAQDALRVWDALHRFVAGWTRLYYCSDEDVQSDCELQNWIGEIFREGFLGLTHLGVPQSFQTAAEMCKFVTMVIFSCSALHSAVNFSQLDFNLCIPNTPATMSRPPSQTKGSVSEEDLLSFLPEVNSSCHVLSVLSLLSQPAIDFVPLCHYNEWYFHSGAMAKLVEDVQKELKIIAKDIADRNSQLELPYPYMSPDYIENSVTI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :.* * *.: :** ..: ::::*: ** :: : * : .:* *::::*. : :.. *.*. *:: . : .: **. :*: : : *:: . :: * :**::::: :::. :* .* * * . . *: : . :: : . .* ::.:. * . :. :::** ** :* *:*** *** ** ::: .:* :*.*:.:*: .** .*:.*: *:::*.::* **. : :*: :.*:: . **:***: . : :: ******.* .. . *:***.*: *** ** :** :: *: *: *:.*. : **:** **:.:**:** * .:*:* * *: .*: : : * *.: :: :. . * *.** :*:*. * :: ** :: :*.* ** :. :* :* .* *: * *** *: :** . :* *.* .: * *: .::*::::: ** *:*:. .*::: :** *.:: ** ** : :. **:::::. *: *.: . * ** :: : :* . . : :. .: .* ::. : :** * :** *: * * **:::", "identical_positions": 165, "similar_positions": 233, "identity": "22.92%" }, { "cls_id": "homologset.agr.MGI:1274784", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A096MK89-1", "uniprot_id": "A0A096MK89_RAT", "id": "A0A096MK89-1", "name": "Adhesion G-protein coupled receptor V1", "aln": "MSVTSEPGMVSSLLLV-YLSALVVSFVCG-EAEIRFTGQTEFFVNETSTTVIRFVIERIGEPANVTAIVSLDGEDTGDFFDTYAAAFIPAGGTNRTVYIAVCDDDLPEPDETFTFQLTLQKPSANVKLGWPRAAAVTILSNDNAFGVISFSTPSSITVTEPRSRNASVSLTLIREKGTYGMVTVTFDVSGGSNPPEEDLSPVRGNITFPPGRATIIHNLTVLDDEVPENDEMFLIQLRSVGGGAEINASRSSVEIIVKKNDSPVKFLQSVYVVPEDDHVLTIPVVRGKDNNGHPIGSDESQVSVRYKVVTGDSTAHAQQNVDFIDLQPDTTLVFPPFVHESHLKFQIIDDLIPEIAESFHIMLLKNTLQGDAVLMDPSTVQVTIKANDKPHGVLSFNSILFERPVVIDEDTASSSRFEEITVVRNGGTHGNVSVNWVLTRNSSDPSPVTADLSPASGTLQFAQGQMLALIPLAIIDDELPEEAEAYLLTILPHTIQGGAEVSEPAQLLFYVQDSDDVYGEIALFPVESQRIESSPSERSLSLSFTRLGGSKGDLKVIYSALYIPAGAVDPLRAKDGILNTSRRNTLLFPEQNYQVTAKLPIRNDAFLQNGAHFLVQLEAVELVNIVPLIPPVSPRFGEIRNTSLLVTPAIANGEIGFLSNLPIILHEPNDSAAEVVSIPLHRDGTDGQATVYWSLRPSGFNSKAVTVDDTGPFNGSVVFLSGQSDTSINITVKGDDTPELNETVTLSLDRVSVDSDVLKSGYTSRDLIILENDDPGGIFEFSYDSRGPYVIKEGDAVELRIARSRGALVKQFLRFHVEPRDSNEFYGNTGVLEFSPGEREVVITLLTRLDGMPELDEHYWVVLSSHGGRESKLGSATHVNITILENDDPHGIIEFASNGLTVSIRESKGEDVYHAVYG-VVRTRGNFGAVNVSWMVSPNSTQDVFPVQGTVCFGDQENFKNITVYSFADEIPEEMEEFTIILLSATGGAQTGNQTTASLRILRNDDPIYFAEPSVVRVQEGETANFTVLRNGSVDAACTVQYATVDGKASGGEGDFVPVEKGETLVFEVGSREQSVSVSVNEDGVPETDEPFYIILFNSTGDTVVYEYGVATIIIEANDDPNGVFSLEPIDKAVEEGKTNAFWILRHRGHFGNVSVAWHLFQN-ASLQPGREFYETSGTVNFTDGEGTKPVILRAFPDRIPEFNEFYILRLVNISG----AGGQLAETDLQVTVMIPFNDDPFGVFILDPECLEREVAEDVLSEDDMSYIANFTVLRQQGVFGDVRVGWEVLSRELPAGLPPMVDFLLVGVFPSTVPLQPHMRHRHSGTDVLYFSGLEGAFGTVDPKYQPSRNNTIANFTFSAWVMPNAYTNGFLIAKDDSHGSIYYGVKIQTNETHVTLSLHYKTFGSDVTYIAKSTAMKYLEDGVWLHVLIILDDGIIEFYLDGNAMPKGIKSLKGEAITDGPGILRIGAGMDGGDRFTGWMQDVRTYERKLTPEEIYELHAMPARNDLHPISGYLEFRQGETNKSFIVAARDDSEEEGEELFLLKLVSVYGGAQLSEENTTARLRIQKSDNANGLFGFTGACIPEMTEEGSTVSCVVERTRGALGYVRVFYTISQIESEGLHYLVDDFANASGTITFLPWQRSEVLNLYVLDENIPELNEYFRVTLVSAVPGDGKLGSTPVSGASIDPEKETTDITVKASDHPYGLLQFSTGLPPQPEDAMSLPASSVPHITVQEEDGEIRLLVVRAQGLLGRVTVGFRTVSLTAFSPGDYQSIAGTLEFQSGERYKYIFVNITDNSVPELEKSFKVELLNLDGGVSELFRVDGSGSGEGDTDFFLPAVRMHAS-LGVASQILVTIAASDHAHGVFEFSPESLFVSGTEPEDGYSTVVLNVTRAQGALSPVTLLWKVDSDPDGDLAVTSGNITFEVGQRLAHITVEILADEEPELDKTRTVSILNVSSGSLGVLSSATLTILASDDPHGVFIFPNKTRPISVEEATQNVTLSIIRLKGLMGEVAISYATIDDMEKPPYFPPNLARATQGGDYISASGLALFRANQTEAMITISILDDDEPERSESVFIELFNSSLVDKVQNRPIPHSPRLGPKVETVAHLIIVANDDAFGTVQLSAPTVRVAENHVGPIINVTRTGGAFADVSVKFKAVPITAATGEDYSIASSDVVLLEGETTKAVPIYIIDDIYPELEEAFLVQLLNETTGGATLGPLREAVITIDASDDPFGLFGFQNTKFIVEEPEFNSVWVNMPIIRNSGTLGNVTVEWVATINGQLATGDLRVVSGNVTFAPGETIQTLLLEVLADDVPEIEEVVQVQLAAASGGGTIGLDRVAHIVIAANDNPYGSVAFAQSIYRVQEPLQRHSSANITVRRSGGHYGRLLLFYSTSDIDVVALAVEEGEEDVLSYYESPTQGMPDPLWRTWVNVSAVEETQYTCATLCLREHACSAFSVVSGADGPQCFWMTSWVSLTVNSSDFQTYKKNMTKVASLFSGQAVAGSDYEPVTRQWALMPEGDEFANLTVSLLPDDVPEMDECFLISLLEVHLVNITDSFKNQPTIGHPSTSTVLIGLNGDAFGVFVMYSVSPNTSEDGLCVQVQEQPQTSVELVIHRTGGSLGQVMVEWRTVGGTATEGLDFIGAGDILTFAEGETKKTAILTILDDSEPEDEESIFVRLVATEGGSRILPSSDTVTVNILANDNVAGIVSFQTASRSVIGHEGEMLQLHAVRTAPGRGNVTVNWKVTGQNLEVNFANSTGQLFFSEGALNKTIFVHLLDDNIPEEKEVYQVVLYDVKTQGVSPAGVALLDAQGYAAVLTVEASDEPHGVLNFALSSRFVVLPEANLTVQLFVNREFGSLGAINVSYATVPGIASLKNETEGNLAEPEADFIPVVGFLVLEEGETTAAINITVLEDDIPELREYFLVNLTHVDLVMAPLTSFPPRLDSEGLSAQIVIDANDGGQGVIEWQRSRLEVNETHGTVTLVVQRGRAALGHVSLFMYAQNLEAQMGLDYMCTPQILHFADGERFKPVDVVILDDDVPEGDERFQLILTNPSPGLELGTNTIALITVLANDDGPGVLSFNNSGHVFLREPTSLY-VQESVAALVIVREPAQGLFGTVAVQFVVTEVNSSTESKDLVPSKGFIVLEEGVRSKALHISAVLDTEPEMDEHFVCTLFNPTGGARLGAHVQTVITVLQNQAPLGLFSIS-AVENSATSIDVEESNRTVYLNVSRTNGLDLAVSVQWETVSETAFGMRGMDVVFSIFQSFFDKTALDWCFFSVGDSVYGVMLRK----SSLVVYRWQGTFVPVEDLNVESPRTCEAFTIGVSLYLVITHGERNGEKPSINSVYTLASGFRLLLVQTIVISGSCQVRHFTSDTQDYFIIASQRNDSELTQVFRWNGNNFAWHQTLPVRGVLGMALFSRGGS--VFLAISQANIRQNPLLFMWSGSQFINFQELSVS-GITQVEALSSGDDVYLFFAKNTFLGNQNAIDIFVWEMGQSSLRHFQSLDFATVNRIRSFTPASGIVHILLTGQDRSALYCWNSELNAFTFVLEAPSAHDAAFVTVKSLNSSKTLIALVGATDTHVYELAYVSSQSDFIPSLGELMFEPGDREAIIAVSVLDDAVPEEEESFRVQLKNPRGGAEIGTDSSVRVTVRPNDDPYGVVAFAQNSLHKQLEELERDSLVTLNVERLKGTYGRVTVAWEAAGSVSDVFPTSGVISFAEDQAMSTITLTVLADDLPELSEAVVVTLTRIVTEGVEDPSKGATIDQDRSKSVLTILPSDSPYGVVGWHAESLFTRVPEPRENITVLQLHLVRDKGLLGDISIHLIAKPNFLLDINNQATENEDFALQDSVIIMKENIKETQAEVAILPDEVPELDEGLIVAIAAVNLVNPNFPAEQPRVQRPRMESAEIMIEENDDPRGIFSFRVSRGVGGVIIAHEGPQPLNILQVPVIRMAGSFETVNVYWKATPDSAGLEDFLPPYGMLQFADGQVIAPIHITITDDTEFELSETFSISLMSVTGGGRLGDDVLVTVVIPPNDSPFGIFGFEEKTVMVDRSHLSDDPDSYVKLTVVRSPGGKGAVRLHWTIEEKAKDDLSPLNGTLYFDETDSQKSIILHILQDSVLGEDRRFTIELMD-AGEVEISPGKGRASVIILGEKSPS-EVGIASSSRHVIIGEPSATYSGTATISLDRGPGVSGEVTVDWRILPPSRGEFAETSGQLTMLDGQSTATVVIQALDDGIPEEKCSYEFQLTGISEGAVLNEASVTASISMVASDAPYGQFSFSHEQLQVSEAAQKVNVTVARSGGSFGRVRVWYETGSRTAEAGWDFVPTSGELIFEAREKMKSLHIEILDDNLPEGPEEFVLAITRVDLQ-GRGYDFTIQENGLQIDQPPEIGSISVVQIIIMENDNVEGIIEFDPKFTDISVEEGAGVIPLPVMRLRGTYGRVSADFSSRDSSAVPG--GYVLHGGSVTFQHGQSLSFINVSIVDDNDSESEKQLEILLIGATGGAILGRHLVSKITIAKSDSPFGIIRFLNQSKISVPNPNSTMALHLVLERTGGLLGEIQVSWEIVGPSSEELLLPQHGDFADPVSGTVSFGDGEGGVRTITLTVCPHEETEAEETFVVQLKPLK-EAKLDPRAKAVTLTIQKFGDPNGVIHFAPESLSKKMFSEPPPSEGPMLISFLVTRSKGTSGEITVHWELSSEFDLTGDFLSTQGFFTIADGDSEASFDVHLLPDDVPEIEEEYVVQLVSVEGGAELDLEKCTSRFSVSANDDPHGIFALYSDQQSVLIGQN-LIRSIQINITRLAGVFGAVAVTLQILSDNKEDPVATENEERQMVIKDGARYKVGLVPLKNQVFLSLGSNFTLRLLSARLLSGPFYGMPTIHQEANQAFLSVPEEAANSQVGFESTAFQLIDITAGTSQVTVSRRGTYGRLSVAWTTGYAPGSEIPEPIAIGNMTPTLGSLSFLHGEQKKGVLLWTFPSPGQPEAFVLHLSGLRSSAAGGAQLRSAFTTAEIEPLGVFQLSPGSRNITVSEDALIIRICVQRLFGFQGDLIKVSYKTTAGSAKPLEDFEPIQKGEIFFQRFQAEVDFEITIINDQLPEREETFYINLTSVETRGPGKGDVSWRPRLNPDLSVAMVTILDNDDPAGVAVSVPVTAGTVAADSTLLAMEADFTTHPNKSKITTIPYTTEVFAPVTETVDVSAIPEKLVTIH--SAISEEPDLAPGTAQAAVFGTLSLGPPIVYVSEEMKNNTPS-TADIQIQRIGGFAGNVSVTVRTFGGRCAQKEPSVWPFQDVYGIGNLT-WAVEEEDFEEQMLTLTFLNGEREHRIAVRILDDDEPEGQEFFYVFLTDPQGGAEIVRGKDGSGFSAFALILITGSDLHNGIVGFSEESLRGLELREGTDKSSQRLEVTRQPNRAFEEVQVFWRVTLNQTATILQEKGLNLTDELRSVAGVTTCTVGQTQCFIHLELNPKKVHQVEMPFFVELYDVTAGAAINNSARFARIKVSKSGDSQSLVFFSVGSRLAVAHKKATLISLQVARDSGTGMMMSVNFSTQELRSAETVGRILLSPAVSGKDFVRTEGTLVFEPGQKSAVLDVVLTPETGSLNKFPKRFQIVLFDPKGGARIDKVYGTANITLVSDVDSQAVWGLEDLLHQPLHEDVLNRVLHSLNLRVATESTDEQLSAVMFIMEKIMMEGKNQAFSIESRTLLYELLCALINPKRKDTRGFSHFAEVAEHFAFSLLTDVTCGSPGEKSKTILDSCPYLSILALHWSPQQINGHRFEGKEGDYIQIPERFLDAPEP-EVSDGKNACALVQFVEYSSQQWFVAGDNLPALRDKVLSLNVKGRDAQPLPNNNEVLYRIYAAEPR--IIPHTSLCLLWNQAASSWLSDSQLCKVVEDAADYVECACSHMSAYAVYAQTDNLVSYNEAFFSAGFICISGLCLAVVSHVFCARYSMFAAKLLTHMMAASLGAQVSFLASAYASPQLSEESCSAVAAVAHYLYLCQFSWMLIQSVNFWYVLVVNDEHTERRCLLFCLLSWGLPSFVVILLIVILRGIYHQSMPQIYGLIHGDLCFIPNIYAALFTAALVPLMCLVVVFVVFIHAYQLKPQWKGYDDVFRGRTNAAEIPLILYLFALISLTWLWGGLHMAYRHFWMLVLFVIFNSLQGLYVFVVYFILHNQTCCPMKASYTVEMNGHPGPSTAFFTPGSGIPPAG-EMNKSTQNLINAMEEVPSDWERVSFQQTSQASPDLKTSPQNGASFPSSGGYGQGSLIADEESQEFDDLIFALKTGAGLSVSDNESGQGSQEGGTLTDSQIVELRRIPIADTHL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VHN7-1", "uniprot_id": "AGRV1_MOUSE", "id": "Q8VHN7-1", "name": "Adhesion G protein-coupled receptor V1", "aln": "MSVTSEPGMISSFLLV-YLSTLFISFVFG-EAEIRFTGQTEFFVNETSTTVIRLVIERIGEPANVTAIVSLSGEDTGDFFDTYAAAFIPARGTNRTVYIAVCDDDLPEPDETFTFHLTLQKPSANVKLGWPRAASVTILSNDNAFGIISFSTPSSISVIEPRSRNASVPLTLIREKGTYGMVTVTFDVSGGPNPPEEDLNPVRGNITFPPGRATVIYNVTVLDDEVPENDELFLIQLRSVEGGAEINASRSSVEIIVKKNDSPVNFMQSVYVVPEDDHVLTIPVLRGKDSDGNLIGSDETQVSIRYKVMTWDSTAHAQQNVDFIDLQPDTTLVFPPFVHESHLKFQIIDDLIPEIAESFHIMLLKNTLQGDAVLMGPSTVQVTIKPNDKPYGVLSFNSILFERPVIIDEDTASSSRFEEIAVVRNGGTHGNVSVSWVLTRNSSDPSPVTADITPASGTLQFAQGQMLAPISLVVFDDDLPEEAEAYLLTILPHTIQGGAEVSEPAQLLFYIQDSDNVYGEIAFFPGESQKIESSPSERSLSLSLARRGGSKGDVRVIYSALYIPAGAMDPLRAKDGILNTSRRSSLLFPEQNQQVSIKLPIRNDAFLQNGAHFLVQLEAVVLVNIFPPIPPVSPRFGEIRNISLLVTPAIANGEIGFLSNLPIILHEPKDSSAEVVSIPLHRDGTDGQATVYWSLRPSGFNSKAVTLDDAGPFNGSVVFLSGQNETSINITVKGDDIPELNETVTLSLDRVSVDSDVLKSGYTSRDLIILENDDPGGIFEFSYDSRGPYVIKEGDAVELRITRSRGSLVKQFLRFHVEPRESNEFYGNMGVLEFTPGEREVVITLLTRLDGTPELDEHFWVILSSHGERESKLGRATLVNITILKNDYPHGIIEFVSDGLSASIKESKGEDIYHAVYG-VIRTRGNFGAVNVSWMVSPDFTQDVFPVQGTVCFGDQEFFKNITVYSLVDEIPEEMEEFTIILLNATGGAQTGIRTTASLRILRNDDPVYFAEPCVLRVQEGETANFTVLRNGSVDGACTVQYATVDGKASGEEGDFAPVEKGETLVFEVGSREQSISVHVKDDGIPETDEPFYIVLFNSTGDTVVYEYGVATVIIEANDDPNGVFSLEPIDKAVEEGKTNAFWILRHRGHFGNVSVAWQLFQN-ASLQPGQEFYETSGTVNFTDGEETKPVILRAFPDRIPEFNEFYILRLVNISG----PGGQLAETNFQVTVMIPFNDDPFGIFILDPECLEREVAEDVLSEDDMSYITSFTILRQQGVFGDVRVGWEVLSREFTAGLPPMIDFILLGSFPSTVPLQPHMRRHHSGTDVLYFSGLEGAFGTVDPKYQPFRNNTIANFTFSAWVMPNANTNGFLIAKDDSHGSIYYGVKIQTNETHVTLSLHYKTFGSNVTYIAKSTVMKYLEEGVWLHVLIILDDGIIEFYLDGKAMPRGIKSLKGEAITDGPGILRIGAGMDGGARFTGWMQDVRTYERKLTPEEIYELHAVPARTDLHPISGYLEFRQGESNKSFIVAARDDSEEEGEELFLLKLVSVDGGAQISKENTTARLRIQKSDNANGLFGFTGACIPEMTEEGSTVSCVVERTRGALGYVHVFYTISQIESEGINYLVDDFANASGTITFLPWQRSEVLNLYVLDEDMPELNEYFRVTLVSAVPGDGKLGSTPISGASIDPEKETTGITVKASDHPYGLMQFSTGLPPQPEDSMSLPASSVPHITVQEEDGEIRLLVIRAQGLLGRVTVGFRTVSLTAFSPEDYQSTAGTLEFQSGERYKYIFVNITDNSIPELEKSFKVELLNLDGGVSDLFRVDGSGSGEADTDFFLPPVLPHAS-LGVASQILVTIAASDHAHGVFEFSPESLFVSGTEPEDGYSTVVLNVTRTRGALSAVTLQWKVDSDLDGDLAITSGNITFETGQRIASITVEILSDEEPELDKALTVSILNVSSGSLGVLTNATLTILASDDPYGVFIFPNKTRPLSVEEATQNVALSIIRLKGLMGEVAVSYATIDDMEKPPYFPPNLARATQGGDYISASGLALFRVNQTEATITISILDDAEPERSESVFIELFNSSLVDKVQNRPIPHSPRLGPKVETVAHLVIVANDDAFGTVQLSATSVHVAENHVGPIINVTRTGGTFADVSVKFKAVPITAAAGEDYSIASSDVVLLEGETTKAVPIYIINDIYPELEETFLVQLLNETTGGATLGPLREAVITIEASDDPYGLFGFQNTKFIVEEPEFNSVRVNVPIIRNSGTLGNVTVQWVAIINGQFATGDLRVVSGNVTFAPGETIQTLLLEVLADDVPEIEEVVQVQLAAASGGGTIGLDRVANIVIPANDNPYGSVAFVQSVFRVQEPLERSSYANITVRRSGGHFGRLLLCYGTSDIDVVARAVEEGE-DVLSYYESPTQGVPDPLWRTWVNVSAVEETQYTCATLCLKERACSAFSVVSGAEGPRCFWMTSWVSGTVNSSDFQTYKKNMTRVASLFSGQAVAGSDYEPVTRQWAVILEGDEFANLTVSVLPDDAPEMDESFLISLLEVHLMNISDSFKNQPTIGHPNTSAVVIGLNGDAFGVFIIYSVSPNTSEDGLCVEVQEQPQTSVELVIYRTGGSLGQVMVEWRVVGGTATEGLDFMGAGDILTFAEGETKKMAILTILDDSEPEDNESILVRLGATEGGSRILPSSDTVTVNILANDNVAGIVSFQTASRSVIGHEGEMLQFHVVRTPPGRGNVTVNWKVVGQNLEVNFANFTGQLFFSEGTLNKTIFVHLLDDNIPEEKEVYQVVLYDVKTQGVSPAGVALLDAQGYAAVLTVEASDEPHGVLNFALSSRFVVLQEANVTIQLFVNREFGSLGAINVTYATVPGIVSLKNNTEGNLAEPESDFIPVVGSLVLEEGETTAAISITVLEDDIPELKEYFLVNLTHVDLIMAPLTSSPPRLDSEGLTAQIVIDANDGAQGMIEWQRNRFEVNETDGVVTLVAQRSRAALGQVSLFMYAQNLEAQAGLDYMRTPQILHFTDGERFKHVDVMILDDDMPEGDERFQLLLTNPSPGLELGKNTIALITVLANDDGPGVLSFNNSGHIFLREPTSLY-VQESVAVLVIVREPAQGLFGTVAVQFVVTEVNSSTESKDLSPSKGFIVLEEGVRSKTLRISAILDTEPEMDEHFVCTLFNPTGGARLGAHVQTLITIFQNQAPLGLFSIS-AVENSATSIDVEESNRSVYLNVSRTNGLDLTASVQWETVSETAFGMRGMDVVFSIFQSFFDKTALDWCFFTVEGSVYGVMLRK----SSLVVYRWQGTFVPVEDLKVESPKTCEAFNIGVSPYLVITHGERSGEKPSINSVYMLTAGFRLVLIQTIIISGSCQVRHFTSDSQDYFIIASRRNDSELTQVFRWNGNNFAWHQTLPVRGVLGMALFSRGGS--VFLAISQANIRQTSLLFTWSGTQFINFQELPIS-GITQVEALSSGDDVYLCFAKNTFLGNQNAIDIFVWEMGHSSLRYFQSLDFAAVKRIRSFTPASGIVHILLTAQDGSALYCWNSELNAFSFVLEAPAAHDAAFVTVKSLNSSKTLIALVGATDSHLYELTYVSSQSDFIPSLGELIFEPGDKEAIIAVNVLDDTVPEKEESFRVQLKSPRGGAEIGINSSVRVTVLANDGAYGVVAFAQNSLHKQLEELERDSLVTLNVERLRGTHGRITVAWEAAGSVSDVFPTSGVISFTEDQAMSMITLTVLADDLPELSEAVVVTLTQIVTEGVEDPLKGATIDQSRSRSVLTILPSDSPYGAVRWHTESLFNRVPEPTENITVVQLHIVRDKGLFGDISIHLIAKPNFLLHINNQATEDEDFVLQDSVIIMKENIKETHAEVAILPDEVPELDEGLIVTIAAVNLVNPNFPAEQPRVQRPRMESAEILIEENDDPRGIFNFHVVRDVGGVIIAHEGPPPLNVLQVPVVRMAGTFETVNVYWKATPDSAGLEDFQPSHGMLQFADGQVIAPILVTIIDDSEFELLETFTISLVSVTGGGRLGDDVSVNVVIAPNDSPFGIFGFEKKTVMVDGPLLSDDPDSYVTLTVVRSPGGKGAVRLHWAIEEKAKDDLSPLNGTLYFDETESQKSVILHTLKDGMVGEDRRFIIELTA-ADEVEISPVKGSASVIIRGDKSIS-EVGIASSSRHIIIGEPSATYNGTAIIDLVRGPGVSGEITVNWKILPPSRGEFVETSGQLTMLDGQTAATVVIQVLNDDIPEEKCHYEFQLTEISEGRMLHEASVSARITMVASDAPYGRFSFSHEQLHVSKAAQRVNVTVVRSGGSFGRARVLYETGSRTAEAGWDFVPASGELLFEAREKMKSLYIDILDDDLPEGPEEFVLAITRVDLQ-GRGYDFTIQENGLQIDQPPEIGNISIVRIIIMKNDNAEGIIEFDPKYTDISVEEDAGVITLPVLRLHGTYGHVSADFSSRGFSAVPG--GYVLRGSSVTFQHGQNLSFINVSIIDDNGSEFEKQFEILLIGATGGAILGRHLVSKITIAKSDSPFGIIRFLNQSKISLPNPSSTMALHLVLERTGGLLGEIQVSWEVVGPDAEEPLPPHNGDFADPVSGTVSFGDGEGGVRSIILRVCPHEETEAEETFIVQLKPLR-EAKLDPRAKAVTLTIQKFGDPNGVIHFAPESLSKRRFSEPPPSDGPLLVSFLVTRSKGTSGDIKVHWELSSEFDITRDFLSTRGFFTIADGESDANFDVHLLPDDVPEIEEEYAVQLVSVEGGAELDLGKCTARFSVSANDDPHGVFALYSDRQSVLIGQN-LDRSIQINITRLAGAFGAVAVRVQILSDNKEDPVATENEERQLVITDGARYKVGLVPLKNQVFLSLGSNFTLQLVSVRLLSGPFYGIPTILQEAKNAILSVPEEAANSQVGFESAAFQLMDIKAGTSQVMVSRKGTYGRLSVAWTTGYAPGSEIPEPIVIGNMTPTLGSLSFVHGEERKGVLLWTFPSPGRPEAFVLHLSGLRSSAAGGAQLRSGFTTAEIEPMGVFQFSPSSRNITVSEDAQTIRICVQRLFGFHGDLIKVSYETTAGSAKPPEDFEAVQKGEVFFQRFQPEIDFEITIINDQLPEIEETYYINLTSVETRGLGKGGVNWRPRLNPDLSVAVVTIVDNDDLTGAAVSVPVTAGTVAVDSTLLAMETGSTTHPNKSKITTIPYTTEVFAPVTETVTVSAIPEKLATAH--SVISVKPDVVPGTVVASVYGTLSIGPPIVYVSEEMKNGTLS-TADILIQRMGGFAGNVTITVKTFGGRCAQKEPSVWPFQDVYGVGNLTTWAVEEEDFEEQLLTLTFLYGERERKIAVQILDDDDAEGQEFFYVFLTDPQGGAEIVRGKDSTGFSAFAVIIISGSDLHNGIIGFSEESQRGLELREGADKNSQRLVVTRQPNRAFEEVQIFWRVTLNQTVTILQEKGANLTDELRFVAGVTTCTGGQTRCFIHLELNPKKVHQVEMPFFVELYDVTAGAAINNSARFAPIKLSKSGAPQSLVSFSVGSRLAVAHKKSTLISLQVARDSGTGIMMSVNFITQELRSAETVGRVLISPAVSGKDFVRTEGTLVFEPGQKSAVLDVVLTPEAGSLNKFPKRFQIVLFDPKGGARIDKVYGTANITLISDADSQAVWGLEDLLHRPLHEDILNRVLHNLNLRVATESTDEQLSAVMLIMEKITMEGRNQAFSIKSRTLLYELLCVLINPKRKDTRGFSHFVEVAEHFAFSLLTDVTCGSPGEKSKTILDSCPYLSILALHWNPQQINGHKFEGKEGDYIQIPERLLDVPEA-EMLDGKNACTLVQFVEYSSQQWFIAGDNLPALKDKVLSLNVKGQSAQPLPNNNEVLYRIHAAEPR--VVPHTSRCLLWNQAAASWLSDSQFCKVVEDASDYVECACSHMSVYAVYAQTDNSSSYNEAFFSAGLICISGLCLAVVSHMFCARHSMFAAKLLTHMMVASLGTQILFLASAYASPHLSEESCSAVAAVAHYLYLCQFSWMLIQSVNFWYVLVVSDEHTERRCLLFCLLSWGLPSFVVILLILILRGIYHRSMPQIYGLIHGDLCFIPNIYAALFTAALVPLMCLVVVFVVFIHAYQLKPQWKGYDDVFRGRTNAAEIPLILYLFALISMTWLWGGLHMAYGHFWMLVLFVIFNSLQGLYVFVVYFILHNQTCCPMKASYTVEMNGHPGPSTAFFTPGSGIPPAG-EINKSTQNLINAMEEVPSDWERSSFQQTSQASPDLKTSPQNGASFPSSGGYGPGSLIADEESQEFDDLIFALKTGAGLSVSDNESGQGSQEGGTLTDSQIVELRRIPIADTHL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WXG9-1", "uniprot_id": "AGRV1_HUMAN", "id": "Q8WXG9-1", "name": "Adhesion G protein-coupled receptor V1", "aln": "MSVFLGPGMPSASLLVNLLSALLILFVFG-ETEIRFTGQTEFVVNETSTTVIRLIIERIGEPANVTAIVSLYGEDAGDFFDTYAAAFIPAGETNRTVYIAVCDDDLPEPDETFIFHLTLQKPSANVKLGWPRTVTVTILSNDNAFGIISFNMLPSIAVSEPKGRNESMPLTLIREKGTYGMVMVTFEVEGGPNPPDEDLSPVKGNITFPPGRATVIYNLTVLDDEVPENDEIFLIQLKSVEGGAEINTSRNSIEIIIKKNDSPVRFLQSIYLVPEEDHILIIPVVRGKDNNGNLIGSDEYEVSISYAVTTGNSTAHAQQNLDFIDLQPNTTVVFPPFIHESHLKFQIVDDTIPEIAESFHIMLLKDTLQGDAVLISPSVVQVTIKPNDKPYGVLSFNSVLFERTVIIDEDRIS--RYEEITVVRNGGTHGNVSANWVLTRNSTDPSPVTADIRPSSGVLHFAQGQMLATIPLTVVDDDLPEEAEAYLLQILPHTIRGGAEVSEPAELLFYIQDSDDVYGLITFFPMENQKIESSPGERYLSLSFTRLGGTKGDVRLLYSVLYIPAGAVDPLQAKEGILNISRRNDLIFPEQKTQVTTKLPIRNDAFLQNGAHFLVQLETVELLNIIPLIPPISPRFGEICNISLLVTPAIANGEIGFLSNLPIILHEPEDFAAEVVYIPLHRDGTDGQATVYWSLKPSGFNSKAVTPDDIGPFNGSVLFLSGQSDTTINITIKGDDIPEMNETVTLSLDRVNVENQVLKSGYTSRDLIILENDDPGGVFEFSPASRGPYVIKEGESVELHIIRSRGSLVKQFLHYRVEPRDSNEFYGNTGVLEFKPGEREIVITLLARLDGIPELDEHYWVVLSSHGERESKLGSATIVNITILKNDDPHGIIEFVSDGLIVMINESKGDAIYSAVYD-VVRNRGNFGDVSVSWVVSPDFTQDVFPVQGTVVFGDQEFSKNITIYSLPDEIPEEMEEFTVILLNGTGGAKVGNRTTATLRIRRNDDPIYFAEPRVVRVQEGETANFTVLRNGSVDVTCMVQYATKDGKATARERDFIPVEKGETLIFEVGSRQQSISIFVNEDGIPETDEPFYIILLNSTGDTVVYQYGVATVIIEANDDPNGIFSLEPIDKAVEEGKTNAFWILRHRGYFGSVSVSWQLFQNDSALQPGQEFYETSGTVNFMDGEEAKPIILHAFPDKIPEFNEFYFLKLVNISGGSPGPGGQLAETNLQVTVMVPFNDDPFGVFILDPECLEREVAEDVLSEDDMSYITNFTILRQQGVFGDVQLGWEILSSEFPAGLPPMIDFLLVGIFPTTVHLQQHMRRHHSGTDALYFTGLEGAFGTVNPKYHPSRNNTIANFTFSAWVMPNANTNGFIIAKDDGNGSIYYGVKIQTNESHVTLSLHYKTLGSNATYIAKTTVMKYLEESVWLHLLIILEDGIIEFYLDGNAMPRGIKSLKGEAITDGPGILRIGAGINGNDRFTGLMQDVRSYERKLTLEEIYELHAMPAKSDLHPISGYLEFRQGETNKSFIISARDDNDEEGEELFILKLVSVYGGARISEENTTARLTIQKSDNANGLFGFTGACIPEIAEEGSTISCVVERTRGALDYVHVFYTISQIETDGINYLVDDFANASGTITFLPWQRSEVLNIYVLDDDIPELNEYFRVTLVSAIPGDGKLGSTPTSGASIDPEKETTDITIKASDHPYGLLQFSTGLPPQPKDAMTLPASSVPHITVEEEDGEIRLLVIRAQGLLGRVTAEFRTVSLTAFSPEDYQNVAGTLEFQPGERYKYIFINITDNSIPELEKSFKVELLNLEGGVAELFRVDGSGSGDGDMEFFLPTIHKRAS-LGVASQILVTIAASDHAHGVFEFSPESLFVSGTEPEDGYSTVTLNVIRHHGTLSPVTLHWNIDSDPDGDLAFTSGNITFEIGQTSANITVEILPDEDPELDKAFSVSVLSVSSGSLGAHINATLTVLASDDPYGIFIFSEKNRPVKVEEATQNITLSIIRLKGLMGKVLVSYATLDDMEKPPYFPPNLARATQGRDYIPASGFALFGANQSEATIAISILDDDEPERSESVFIELLNSTLVAKVQSRSIPNSPRLGPKVETIAQLIIIANDDAFGTLQLSAPIVRVAENHVGPIINVTRTGGAFADVSVKFKAVPITAIAGEDYSIASSDVVLLEGETSKAVPIYVINDIYPELEESFLVQLMNETTGGARLGALTEAVIIIEASDDPYGLFGFQITKLIVEEPEFNSVKVNLPIIRNSGTLGNVTVQWVATINGQLATGDLRVVSGNVTFAPGETIQTLLLEVLADDVPEIEEVIQVQLTDASGGGTIGLDRIANIIIPANDDPYGTVAFAQMVYRVQEPLERSSCANITVRRSGGHFGRLLLFYSTSDIDVVALAMEEGQ-DLLSYYESPIQGVPDPLWRTWMNVSAVGEPLYTCATLCLKEQACSAFSFFSASEGPQCFWMTSWISPAVNNSDFWTYRKNMTRVASLFSGQAVAGSDYEPVTRQWAIMQEGDEFANLTVSILPDDFPEMDESFLISLLEVHLMNISASLKNQPTIGQPNISTVVIALNGDAFGVFVIYNISPNTSEDGLFVEVQEQPQTLVELMIHRTGGSLGQVAVEWRVVGGTATEGLDFIGAGEILTFAEGETKKTVILTILDDSEPEDDESIIVSLVYTEGGSRILPSSDTVRVNILANDNVAGIVSFQTASRSVIGHEGEILQFHVIRTFPGRGNVTVNWKIIGQNLELNFANFSGQLFFPEGSLNTTLFVHLLDDNIPEEKEVYQVILYDVRTQGVPPAGIALLDAQGYAAVLTVEASDEPHGVLNFALSSRFVLLQEANITIQLFINREFGSLGAINVTYTTVPGMLSLKNQTVGNLAEPEVDFVPIIGFLILEEGETAAAINITILEDDVPELEEYFLVNLTYVGLTMAASTSFPPRLDSEGLTAQVIIDANDGARGVIEWQQSRFEVNETHGSLTLVAQRSREPLGHVSLFVYAQNLEAQVGLDYIFTPMILHFADGERYKNVNIMILDDDIPEGDEKFQLILTNPSPGLELGKNTIALIIVLANDDGPGVLSFNNSEHFFLREPTALY-VQESVAVLYIVREPAQGLFGTVTVQFIVTEVNSSNESKDLTPSKGYIVLEEGVRFKALQISAILDTEPEMDEYFVCTLFNPTGGARLGVHVQTLITVLQNQAPLGLFSIS-AVENRATSIDIEEANRTVYLNVSRTNGIDLAVSVQWETVSETAFGMRGMDVVFSVFQSFLDESASGWCFFTLENLIYGIMLRK----SSVTVYRWQGIFIPVEDLNIENPKTCEAFNIGFSPYFVITHEERNEEKPSLNSVFTFTSGFKLFLVQTIIILESSQVRYFTSDSQDYLIIASQRDDSELTQVFRWNGGSFVLHQKLPVRGVLTVALFNKGGS--VFLAISQANARLNSLLFRWSGSGFINFQEVPVS-GTTEVEALSSANDIYLIFAENVFLGDQNSIDIFIWEMGQSSFRYFQSVDFAAVNRIHSFTPASGIAHILLIGQDMSALYCWNSERNQFSFVLEVPSAYDVASVTVKSLNSSKNLIALVGAHS-HIYELAYISSHSDFIPSSGELIFEPGEREATIAVNILDDTVPEKEESFKVQLKNPKGGAEIGINDSVTITILSNDDAYGIVAFAQNSLYKQVEEMEQDSLVTLNVERLKGTYGRITIAWEADGSISDIFPTSGVILFTEGQVLSTITLTILADNIPELSEVVIVTLTRITTEGVEDSYKGATIDQDRSKSVITTLPNDSPFGLVGWRAASVFIRVAEPKENTTTLQLQIARDKGLLGDIAIHLRAQPNFLLHVDNQATENEDYVLQETIIIMKENIKEAHAEVSILPDDLPELEEGFIVTITEVNLVNSDFSTGQPSVRRPGMEIAEIMIEENDDPRGIFMFHVTRGAGEVITAYEVPPPLNVLQVPVVRLAGSFGAVNVYWKASPDSAGLEDFKPSHGILEFADKQVTAMIEITIIDDAEFELTETFNISLISVAGGGRLGDDVVVTVVIPQNDSPFGVFGFEEKTVMIDESLSSDDPDSYVTLTVVRSPGGKGTVRLEWTIDEKAKHNLSPLNGTLHFDETESQKTIVLHTLQDTVLEEDRRFTIQLIS-IDEVEISPVKGSASIIIRGDKRASGEVGIAPSSRHILIGEPSAKYNGTAIISLVRGPGILGEVTVFWRIFPPSVGEFAETSGKLTMRDEQSAVIVVIQALNDDIPEEKSFYEFQLTAVSEGGVLSESSSTANITVVASDSPYGRFAFSHEQLRVS-EAQRVNITIIRSSGDFGHVRLWYKTMSGTAEAGLDFVPAAGELLFEAGEMRKSLHVEILDDDYPEGPEEFSLTITKVELQ-GRGYDFTIQENGLQIDQPPEIGNISIVRIIIMKNDNAEGIIEFDPKYTAFEVEEDVGLIMIPVVRLHGTYGYVTADFISQSSSASPGGVDYILHGSTVTFQHGQNLSFINISIIDDNESEFEEPIEILLTGATGGAVLGRHLVSRIIIAKSDSPFGVIRFLNQSKISIANPNSTMILSLVLERTGGLLGEIQVNWETVGPNSQEALLPQNRDIADPVSGLFYFGEGEGGVRTIILTIYPHEEIEVEETFIIKLHLVKGEAKLDSRAKDVTLTIQEFGDPNGVVQFAPETLSKKTYSEPLALEGPLLITFFVRRVKGTFGEIMVYWELSSEFDITEDFLSTSGFFTIADGESEASFDVHLLPDEVPEIEEDYVIQLVSVEGGAELDLEKSITWFSVYANDDPHGVFALYSDRQSILIGQN-LIRSIQINITRLAGTFGDVAVGLRISSDHKEQPIVTENAERQLVVKDGATYKVDVVPIKNQVFLSLGSNFTLQLVTVMLVGGRFYGMPTILQEAKSAVLPVSEKAANSQVGFESTAFQLMNITAGTSHVMISRRGTYGALSVAWTTGYAPGLEIPEFIVVGNMTPTLGSLSFSHGEQRKGVFLWTFPSPGWPEAFVLHLSGVQSSAPGGAQLRSGFIVAEIEPMGVFQFSTSSRNIIVSEDTQMIRLHVQRLFGFHSDLIKVSYQTTAGSAKPLEDFEPVQNGELFFQKFQTEVDFEITIINDQLSEIEEFFYINLTSVEIRGLQKFDVNWSPRLNLDFSVAVITILDNDDLAGMDISFPETTVAVAVDTTLIPVETESTTYLSTSKTTTILQPTNVVAIVTEATGVSAIPEKLVTLHGTPAVSEKPDVATVTANVSIHGTFSLGPSIVYIEEEMKNGTFN-TAEVLIRRTGGFTGNVSITVKTFGERCAQMEPNALPFRGIYGISNLT-WAVEEEDFEEQTLTLIFLDGERERKVSVQILDDDEPEGQEFFYVFLTNPQGGAQIVEEKDDTGFAAFAMVIITGSDLHNGIIGFSEESQSGLELREGAVMRRLHLIVTRQPNRAFEDVKVFWRVTLNKTVVVLQKDGVNLVEELQSVSGTTTCTMGQTKCFISIELKPEKVPQVEVYFFVELYEATAGAAINNSARFAQIKILESDESQSLVYFSVGSRLAVAHKKATLISLQVARDSGTGLMMSVNFSTQELRSAETIGRTIISPAISGKDFVITEGTLVFEPGQRSTVLDVILTPETGSLNSFPKRFQIVLFDPKGGARIDKVYGTANITLVSDADSQAIWGLADQLHQPVNDDILNRVLHTISMKVATENTDEQLSAMMHLIEKITTEGKIQAFSVASRTLFYEILCSLINPKRKDTRGFSHFAEVTENFAFSLLTNVTCGSPGEKSKTILDSCPYLSILALHWYPQQINGHKFEGKEGDYIRIPERLLDVQDA-EIMAGKSTCKLVQFTEYSSQQWFISGNNLPTLKNKVLSLSVKGQSSQLLTNDNEVLYRIYAAEPR--IIPQTSLCLLWNQAAASWLSDSQFCKVVEETADYVECACSHMSVYAVYARTDNLSSYNEAFFTSGFICISGLCLAVLSHIFCARYSMFAAKLLTHMMAASLGTQILFLASAYASPQLAEESCSAMAAVTHYLYLCQFSWMLIQSVNFWYVLVMNDEHTERRYLLFFLLSWGLPAFVVILLIVILKGIYHQSMSQIYGLIHGDLCFIPNVYAALFTAALVPLTCLVVVFVVFIHAYQVKPQWKAYDDVFRGRTNAAEIPLILYLFALISVTWLWGGLHMAYRHFWMLVLFVIFNSLQGLYVFMVYFILHNQMCCPMKASYTVEMNGHPGPSTAFFTPGSGMPPAGGEISKSTQNLIGAMEEVPPDWERASFQQGSQASPDLKPSPQNGATFPSSGGYGQGSLIADEESQEFDDLIFALKTGAGLSVSDNESGQGSQEGGTLTDSQIVELRRIPIADTHL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6JAN0-1", "uniprot_id": "AGRV1_DANRE", "id": "Q6JAN0-1", "name": "Adhesion G protein-coupled receptor V1", "aln": "--------MPAVLALSGLLLMLLTVSVRSESAELRFQGQTQFVVNESSRAIVRLVVERVGDPINVTALVLLQGDDTGDFEATTAAAFLLSSESSKTIFIAVKDDDIPEADETFVFILRLQSSSNGVTVGTPNTATITILSNDNAFGIISFNSSSLITVEESKGRSQYVPLTLLREKGTYGTVTVNFEIFGGPNPASEDLSPDMGNITFPPGRSVVVFSIMIQDDKLPEDDEIFTVQLTEAAGGALLNPNRSSVQIKISRNDAPIRFSKSTLVVPENIGVISLTVTRGRTEDGLLIGSDDKTVSVAYAIITGNGAASATPLTDFVDLQTERMVVFLPGVHEADLRFSIRDDNIPEIAESFQVVLLEETLLGDAVLVTPSLTLVTIEPNDKPYGVLSISPSPIQPHIINED---LNLIYEGMIIVRNGGTHGAVSVQWNITRNSTDRSPVSADLNPAAGTLRFSEGQMSAVLPLNITQDSLPEEAEAFLLKLIPGSVQGGAEVDEPMEMVFFIQDSDDVYGRFGFHPRENQSIQSQPEGRFLSLSFLREGGTLGEVRLTLTALYIPARPLDPSRARDGVLNGTSVNTVLFSSGQSRAQLILPIRNDAFLQNGAHFRIQLDSVELVNITPPIPSMSPRFAGALNISLIITPDIANGEIGFTSNQTVVALEPEDSNSSLITLQLRRDGTDGQAVVFWSLRPTGENKEDVTKGDISPFTGSVTFLSGQSEAVINLTVLADNIPEINETIILTLDRTNVDNQILKPGFTSREIVILENDDPGGVFEFSPVSKGPWFINEGETVELRVIRAQGQLLNQLIRYTVIPSGTAQFYGATGILEFQPGEREVMVALVAKPDGIPELDETFSVVLSSYSTPASRLGNRREVNITVRKSDDPFGVIEFIQPDLDFTINESKALGCLLSILPPLEKSRGRFGNVSIFWILEPTYSGDVKPVQGEIVFAEGEYQKNLTLSSVADEIPEKTENFTITLLNATGGARLGNILSARLSIRANDDPIYFAEPVGQRVREGGVANFTILRAGLANFVTTVNYRFEYGDTSSE--DFIPESNDTMLVFHFGEWMKNISVAVVDDNIPETDEPFYIVLFNATGDAVVYGQITATVVIEANDDANGIFSLDSAQKPGEEGKTNNFYVLRDRGHFGNVTIYWQLFANDTPLEPYQEFVNTSGFITFRTGEKTKPIVLEVISDKLPEFNEFYELRLMNVSGGYPGEGGKLANRDLNASVLIPFNDDPFGVFAIAPDSLEREVAEDVLSVNDMTSVTSLTILRQQGTFGDVRVAWEILSGAFPRGLPPMEDLILMASFPSAVELQPHSRRRHAGTDALFFSGRPGAYGSISAETTLLVPQILANFTLSVWLKPKPNTDGFVVSKGNGNGTVYYGVQVQTNDSHVTIMLHYTTIGSNSTHVARATANTFVED-AWVHVIIAVEDGIIEFYLDGSPIPGGIKSLKGEAIVNDATPIRIGSNPDGEQRFTGLLQDVRLYSSCLNRSQIHELHNQPAKTDLHNVSGYLTYRQEEKEKSFLVEVRDDQEAEGEEVFYLQLVAVQGGARLPMPRPTAILKVMKSDNANGLFSFTGACIPDIAEEGSMISCVVERTRGALDYVYVNYTVTQLDSPADLSNASDFANATGFILFQPGQLSEVLNLLVVNDDLPEVDEHFRVRLVSAKSGDGKPGSTPTSGASIDPEKAVNNVTVKASDHPYGLLQFQTTPVPVG---MIRPALEEARVTVQEEAGVVRLLVARAQGLLGRVMVGYRTSPFTAAGSEDYE---GFLDFLPGERFKYINVTIIDNSVPELDKVFRVELYNPNGGVDPYFASEGSGSGESETDFFLPSFHYHHANLGAAARIIVTIAASDEAHGVFQFGADSLIVNGTEPEEGRSTVVLQVIRTFGALSNVTVYWEADAASEGELVYRSGNVNFEVGQTVRSIYLLISQDDVPELDKTFKVRLTNASHGRLGKETTATLTVLASDDPYGLFVFSDNTRPVRVAEANALVALTIQRRKGLMGRVRVAYRTLRDTDTVLYSTPGVGRASEGNDFIAVVDSVIFSANQSEVNVTLRVLDDNEPERAESVFLELVSVTLIEGLQPRPVALSPRLGPRNVTIAQVIIEASDDAFGVLQLSSSAVSVPEYYTGPIINVTRIGGIFADVSVKFRAVPLTARVGEDYRVASSDVVLLEGESSKPVPILIINDVVPELEETFRIELLNQTTGGALLGDLTQAIITILPSDDPFGLFVFQAAPITIEEPALTAFEVSVPIVRNAGTMGDVAVQWRATVNGRPATGDLRPVSGEVMFSPGETLKTLKVEVLPDDVPEIEEIIKVELVSATSGGNIGLEKVVDTIVPANDNPHGTVYFEQAVYRVQEPLEGIYIANVTIRRSGGNFGMLEVVYSTLEVDIVSNALKEGR-NFLVYYDSRLAGVPSNAIRRPINITTSTNVLNFCAAFCLRERACQAFSFTN-TTTPSCFWVTSGVSQLSPSPQTFTYLKNTTATASLFSSQAVAGSDFITMTAQTTTMLDGSGVANLTVPILTDSLPEMDESFIIKILKVSLVNVTATARNLPTIRQPDTALVTIGMNGDAFGIFLLYSINPNATQEGLYLEVREEPKTTVLLVIERRGGSMGQVTVEWKYVGGSATPNADFNGTGETLIFAEGDVKKTLEFIITDDTEPENNETLQIGLVSTEGGSRILPSSDTVTILILANDNAAGVVGFHTASRSRIVREGESVTLLVERTAPAIGNVAVDWRIEGPLVPTTFADTSGTLFFSEGILNNTIVLKLLEDTTPEDREEYRVILSNIQTTGVTKTGIAALSAQGREAVVSVEASDEPFGLLSIAPSSLQVTTDEKNTTIRIYINREFGASGAVNISYETVRGSLQDLRQTEGALAQPGQDFRYVSNSVIMQDGQTSVSIPITIIDDDIPELQEFFLVNITSAVLITTLPT--APKLNTEGLVAEIIINANDGIRGIIGWQNIDYVVNETIGVLTLVAYRDAGTYGNVSLFFYAQNLEAQLGLDFNATPSMIYFVDGERHKFIEVQILDDAVPEGGETFQLILANPSAGLQLGENTTATVMILANDDGHGIISFNNSEHFLLREPTSVSGLGTSVATLYIIRDPPQGTFGTVTVQFTITDVNGSLYTDDLTPSSGFVVLEDGVRYKTLEIWAVLDAEPEMNETFTVTLSNPTGGARLGVSLQTFITVLENQAPLGLFRISPSINRTLDTMTVEEHMGTVFLTVSRSNGLESAVSVEWETRSGTAFGMRGEQPVLAVYQSIRDSFASVWCSVPSGDAALVLRLIKGLTQNQTVLYKWQGVFVPVEFVSIQNPKSCVGFTVNGSSYVAVSHADNTVSLTTNISLFRVQADLNLTLEQTFSVSG-FSVKHFSTDLKQYLIASS--------EIFVWNRGSFFLHQSLELQDIIAAVPFRRGSSNVQHLAVCRNRTSAACFIYQWTDGRFQNPQPLALNTEVKQVESHQMGGDTFLFIVT---EGLNPACEVFLWGSQQTVFQQTQSILVPGLFSVHPFTTPSGIFHLLLAGVNGSALYSWRSELRQFAEMLKSASAQEFLYLPVPSINSPKSLILASGKSSSLVYELTSVSNQSDFIPSSGELFFQPGVQELEIAVNVIDDDVPEEEEHFRVSLKNPKGGAEIGFRGQVTFFIPANDDTYGIIGFSQNSLMREVEELQSDNPVSLSIERRRGRFGRLTVHWSAYGSLDDIFPTSGVVTFSESQAVATISLNVLADDIPELAEKVTIVLTKVTTIGIIDPSRGASIDYQRAQANLTIRANGSPYGVIGWHLDSQYFITPEPQKSPSNITLSIVRDQGSSGNVLVYYSTKPALHLLPLNQASGGTDYVAKEATVVMMENATVVLVFLTILPDDIPELAETFFVNITRVEVLGGDTGAAQPSVKRPGLEIAEVTIQENDDPRGVLSFNVSKDVSGAVLAFEVPSPGNVLRLAVMRMAGIFGRLVLYWETQSVTASTEDFTPSSGNITFQDGQAMAYIEITIIDDTIVESTETFMVKLIRVIGGARLGVETSVVVSIPANDSPFGRFGFEELKVSVSEPQFLNDPASVATLTVVRSSGGEGVVHLIWLLQEESRDDLSPRNGTLIFNGTESKKTLVIQALADAVLEGEESFTIQLLSPKNEPVIDPVRGVATVVIRPDVGALGTVGIADSSRNVLIGEPICSYNGTALISLIRGPGIFGEIEIFWNITTAAVSEFEETSGKVVMKDRQSAATIQLKALDDEIPEERRVYQLRLSSLTPGSVINPDRQFASITMAASDLPHGLFSFSQASLRATEEDRAVNVTIVRSMGLFGSVWVSFHTEGRTAISGQDFGQSSGRPLFRPGESSRVIPLVIFDDDLPEGPEEFFLNITLVELLNASSMDFTVREYGLQIDQPPAIGNLSSLMVIIQKNDNAEGILEFDPKYVNNTVEEDVGTLSIPVLRRVGSYGQVTVQFVSKGLTAQPDS-DYILLNGSITFQHGQTLSYINVSIVDDTESEFNEIFELQLTGATGGAILGAQLIARITIAKSDSPNGVVRFINQSAITIPNPNSTVRLSLFAERADGLLGDATVMWHIQGPNSNEVLPSMNTDIEP-VNGTFSFRDGEGGVRSIDLKILPHGEVEVTEKFIIMLSVISGEMGVDPRAGSVTLTIEKFGDPNGIVQFTEQDLKERIYSEPSDSEGPLKVSVLVTRREGVMGNITVFWEILSDADTSGDFAALRGSVIILAGQRLAEIILTLLPDSVPELEETYTLRLTSVEGGAELDLNRSSTRLKVRANDEPHGVFVMYSQNQSVVVNAADRSRQLIISVNRLAGAFGNASVGYRISFTTPGQSFTEDTITGNILVKDGEREASIRVPVSSQVFFVTGFNFSVELTDVTLIGPLLGSPPRIQLESKLAVVSVPEVAANPVVGFASLALRVLDIESGQCEALVTRTGLYGNITVRWSSGFPPG-QTPPGYQPGEILPRSGSIMLAHGQRSELISFTALNNISVVTAHAIYLTSVESESPGGARLRTGYTVAEVEPLGLYQFHPNSQHLVIEEDVQTITLYVQRFYGFRSNRSSVSYRTWPGTAQPDKDYVPVTDGQLLFDSRQTSASIRLSILDDTLTEPDEDFYVNLTSVRVLSTTLPLITAQPGIVQKNSISTVTIRAND--------------------------------------------------------------------------------------VVSGFLSIGPAVKLISEDSVEDSPQQKLQLRVRRTAGLSGVVSAKIRAYAGLKTPLVDASQFHREHKGT-----WALEGEDFALETQSVTLLEGQNEVEVTVIMLNDQEPEGQEAFFIYLSDAEGGAQIVSVPDELGFTSFAKIIILGSDLQNGIVGFSLSSLSGQVLDEDSVNRTVTLVLQRQENRAFEDVLVFWRVTFSTTDHALVSHGVDLSKELLQTSGTSIRRKGEVLCALKLEVQPDKNPEYEVWFLVEVYKVGEGAAINQTARFANITMLESDDPRGLVYFAQGSRLPVVTLKATSVSLQIYRDASTASSISVEYRMQELPKVESIGPSLVWPAVAGQDFVMSEGTLTFEIGQSSAGLNIDLTPNIGSSNLTPKRFQVVLSDATGGARVHPEFGLANVTLVSDTETQAVWALLDQLHQPLEETIINRVLHALINKVSRDITPEQLMAVLDASSKILSDAEQTPLKDSSRGLTYDLLCAMANPNRTDTQGVSQLSEVAERFAYSLLTDIKCGAEGKRGITILDNCPYFTIAAHHWYPMQINGHTFIGKNTDTFTLPETLLEVPALPADSTAPSACYKVHFTEYSTEHWFLTNKKPSALNGKVFSVSLYGRGSKPLSEGQEVVYRIHTPDRRGKPKPSQSLCLLWNQAAESWLSDGQFCRLVDDTQNYVECACSHLSIYTAYAEIESLASFNEAFYAAGFICISGFALAMVSHLMCARFLMFAAKLLTHMMVACLGTQICFLVSAFRGRMFSEDSCAALGLFFHYFHLSQFGWMLVQAINFWQILVMNDEHTERRYLLYFLLSWGLPALVIIVLVVVLLGGFGWSIHSVYGLVQGDLCFIPNVYAALCTAALVPLICLVGVLVIFIHAYQVTQQWKAYDDIYRGRTNSSEVPMMLYLFALVTLVCVWAGLHMAYRYIWMLILLVIFNIFLGLYVFSVYFVMHNQLFWPGKATYTVEMNGHSSPDSIYQSTGAATVGGG-EISKSTQNLISAMEEISADWERASLRPSSQPSSIFKPSPQD-EAYITEGGFINTSLVRDEESQEFDDLIFALKTGSGLNVSDNESIHGSHDGGSMANSQIVELRRIPIADTHL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : * * *. * . .:*:** ***:*.***:* :::*:::**:*:* ****:* * *:*:*** * ****: : :.:*::*** ***:**.**** * * **..* .*.:* *.:.::**********:***. . *:* *.:.*. :.***:******* * *.*:: **.**..***.* *********:.::..: : **::**:**:* :** .. *** :*..*.*::* :.:**:*:.* :* :***: :: :.* **: .:* ****: **: * : * :.:* * **:***.: :** * :**:.*:*.* ** ********:::**::** *****: ** . ***:.****:****:.. :: :: :: :* : :******** **..* :****:* ***:**: *::*.*:*::*** * :.* : :*.*******:** ::* :::*****.** :::*::****:*** : :.* *.* *:*.* * ****: * **: *:::: :.***** .:** :*::*:** : . ::*.. : :. *************** :**::* *:** * **.:****. * **::** ******** ** .:: **:* :.:: : *:********.*:***:*:* *.: ** .* .**.*** *****.:: **:*: .*: **:***: *:***..*:.::**.*:***:::*********:**** *:**:.*:**::***:: *::* *::*:::: * * : :*** *:*** *****::::*::: ** ***** : *:***:. *:** ****: :.* *.*:*** . .* *.***. :: : :.**.** *.: *::.* : ** **** : *.: * **:*: *. *****: *:**: **..****: * :* * * ****:***** **:** .****:** * .: . *:* *.::. ** * .:. *:*..*. :.:*: * :*.:*********:*:*:***:*** .**::******.**:***:. :*. ****** *::**.**:**.*:: *:** * :.*:* :** :*** :.* ** :**::*..:.*::******* *:*:*:** **:**: :::.:*::********:* : *:.*********** :**: ::.:*:*****.****::.**:** :. ***** *::*:. **::* ** * *::*:***.*:*:* **:*::..: : :****:*.*: *:. *:**:::*.:.:*::****::***::***: ***.*:**: *::*::*. .::*: .*:*::* ::**********..:* **********.:.. :***:. :* **** :**** *. *. .:*:*** **:.*** :**** :** *.:***:: .***.: ****:* *:**:* ***::. ..** * : *********.*******:::**** :***********.** * **::*::: . ..*****:* * * * * *****: *:::::**::*:*** **** .**** **** ********* ...:*:*********:**.* * * ** . .::**:** * :**** ********* . :** .:** .. **: * *:* .***:*** :.* ***:***:* *:*** * :*** * :*****:.: :****.. : : **.*::*:*******.*****:*..:**:*.*****:* ***.*:* * *:** **: *: *: :*:*. ***:.** ** * : * *: *****: .* : ..* * ** .****:******:*:*:*.::.**: * **. ::*:* * *****.* ::* *: * :. * .*.:.**::* *:*.. . .:* .**:*. ::: :*** ****:****:**.. :*: :* *.:. ******: *:*:::* *.*****.:***:. * *.* :.******** ** ********:***:** .**** :***********::*.*** :*:*: *****:* ::*:*:***** ** * :*:* * .****:*** ** : : :*** :.:. *.:**:**:**:*:*:*:* * :**: ****** ***:* *:****::** :***.********:::*:*. *:.**.***:::.. ::.***:*:*:* * * ::******: **:*:*****::* * : *.* ::*:*: *::**. :.* **:* *:*. * :*::: : **::**:*:**.***. . : * ***:** :* ..: ** ** * .*****.*******: .:* * : : :*. .*****.:*.*. *****.*:*.:*:* *:*:: : :* *** :*. : * *.:******:*::*.:.**::::** ::*:*:*:* * *:* * ***:*** ***: ***:** . ** *:*: * ****:.** : * **:***::*:: : * ************** : ******.**:*.*:***** * :*** : : . ** *. ***:*:*:: * : .**: :* ***.** **.*:.::**:*. **::* *:*:* :::* **. :*:* *.*** **::*******.*:*.:* ** * * * *:::::*****: **:*::* ** * . .:* * **:* ** : . :::::*:*:.:* **:::**:***.*:****:* . * : * .*:*::*** *:::*:**** :*:* **. **** * :***. *. . *:****.******** ***: ** :::*.****.* ::: **** :***.* ***:*:***.**:** ** * : :****** *::***** *.:*****:: : ***.* *:*:*.** ****:*** :*:**.* :.** **.*::***:*** *:*.* *:**:****:* *. ** *********. :**.**:::******** ** :::. :: :** :*:*.***:**:: :.**:*** * ******* : *::::**: *. * ** .. . : * * .. .:*:*** *:*** :.::.*::* .*.:. * *..::* :.. . .: *:: . :.:.* * **: : .*::*::* ::*:* :* ::* ** ..* **.* ::.:: . * :*.* .**:.: . ::: *:. * * * :.:. .:**: . ..* :* :. * : : ::*:* :: :: **: .. : ::.**..*** *:** . : ****.*.** . *: :*: .:* : :.* *:**.*.** * . :***: :*.:****** ***:*:** :* ***.::** ***:** *:*.**.*:****** ..* . : .**..**::.*:**** :::**:: *. *:*.:** :* .**:*: *.* **:.*:******: *:*.*.:: *:*.:***::***:* * :.**::.* *: *. :**:** .*::: :* ...**:* : *: * : ..** :. : : * :.**:* *:: :: ::* : * ***: . *:. ::: ::* ** . . . ::****::*** * ::* *: *:::. : : ** *:** :* **: *:*******:: *.* :... .: *.* * * *:*::.*:*:** * : :**:: . :*. *** *. * : * * *. * * :** **: .* *** :.*: * **.*** :. * * *. ****** ****: .* :. . :** * ..******.**:*.*:* * ::*:::.:*** **** *: *:*:*::::: * * :: :. * *:* .* *.* :* *:::* : **** ***:::**** ..*.*** *.* ****: **: : *.* ..: .** ****::.* * *::. : ::.*:* ****: *:::*: :: * :: * *::.*** *:* *:**: .*:.: : **:*: ** * ** . : :.* . ** :* ** ::*. :*.. * : : : *:**: ******* * ** *:* . . ***::* ******** **.:* : :** :***.***:*****:. ***..* : :**:* *:** *:.:* *:. :* *. .*:* ..::******.**:**:**:**. ** :: :*: * ******:** :*:::* ******* *::**:*** *::.**.**: * *. **:.****: * *. **.::* * . : *: *.* . * :******:* * : ** * *. *.*:: * : * :*.** *****::******:::*: : *.:: :*** :**: ::.:* * :*. *:* *.**: *: * : ** : * . * *: *.: : ****.***:** *.::*.********** :. : :.* ***:***:*.:**:.**:::. *.: *.:.****.** .:* :* :... :. ::::.** **:..***: * **::.* . *:. : . * * *:: *.:.*.* ***. *** * *:::::* :* ... ::* * ** ::* *::*:.** : * *:: * **: : **:. : : : :: . . *..::*:.:.*.:.***:**:.: .**:**:*::*: ..*::: :.**. * : ***::**:.: .***.* .*:*:* :*: .: .*:::*: *.. .:.::*::* *.* :* :*:*****. . :. * : . *:: :** ** : * :*:**.: :.*: :.: . . :: ::* .*::* *: .::::. : .: * **:* *** : :: :* *:.* .::* :*:*::.**** *:::*::.:***:** * **::** ::* ****:***:*** .* * * *.: * : ** *****:* :*****:. * * ..* :* .** .:*.: *:. * : :*::*.* : *: *:**:*.. *****::**** *.: :*. .:.** *: ****.*. *:* :***: **:.*. :**:: *** ..*::* :: **::*:*** :****.** ** *: *:: ***: ** * *****:** *..****:. :* **:**:**.::**:*.* * **:*:.: ::***** : :*: : * *** *:: .** :.. .:. ** * *::** : **:*.**:*.*:: **:*.**:****::.**: *::. ****.***::* * ** * ***** * **: * : :** :*:. . .:* *:*.***:::**::..: .:*..**:*:.: *:.:: *.:.:**:***::.: * * * ******** *****.*:*::*::: :********:* *:.**. :. *:****:::*:*****:.**::**::***. ***********.*.**:*: **.**: . ::*:**:*:. . **::*.**.***:*::*** :**:.******* **: *******::*:*:*:::* * : *: .:***::********:**** ******* *** *:*:******:. ***.***::*****::*:*::******:::. :*.****** ::***:*:**** : ***** ***::*** * **:********..*.: : :.*:. .* *:.*******.****:..**** *:: **.*. :*.***: :: :.**: **: *****************:**.****** :**::**::::****************", "identical_positions": 2859, "similar_positions": 1974, "identity": "45.16%" }, { "cls_id": "homologset.agr.MGI:1274787", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4G073-1", "uniprot_id": "TRDMT_RAT", "id": "Q4G073-1", "name": "tRNA (cytosine(38)-C(5))-methyltransferase", "aln": "MEPLRVLELYSGIGGMHHALRESRVPAHVVAAIDVSTVANEVYKHNFPHTHLLAKTIEGISLEEFDKLSFNMILMSPPCQPFTRIGLQGDMSDRRTNSFLYILDILPRLQKLPKYILLENVKGFEVSSTRGLLIQTMEACGFQYQEFLLSPSSLGIPNSRLRYFLIAKLQSEPLCFQAPGQILMEFPNSGTVQPQEYAVVEEGKLRVRTREPDVCLDSSSTQCSGQDSILFKHETAADIDRKRQQDSDLSVQMLKGFLEDG-DTAQYLLPAKSLLRYALLLDIVKPTSRRSMCFTKGYGSYIEGTGSVLQTAEDVQIENIYKSLPDLPP------------EEKIAKLSMLKLRYFTPKEIANLLGFPPEFGFPEKTTVKQRYRLLGNSLNVHVVSKLLTVLCE------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O55055-1", "uniprot_id": "TRDMT_MOUSE", "id": "O55055-1", "name": "tRNA (cytosine(38)-C(5))-methyltransferase", "aln": "MEPLRVLELYSGIGGMHHALRESHIPAHVVAAIDVNTVANEVYKHNFPHTHLLSKTIEGISLEDFDKLSFNMILMSPPCQPFTRIGLQGDMTDPRTTSFLYILDILPRLQKLPKYILLENVKGFEVSSTRGLLIQTIEACGFQYQEFLLSPSSLGIPNSRLRYFLIAKLQSEPFPFQAPGQILMEFPKIVTVEPQKYAVVEESQPRVQRTGPRICAESSSTQSSGKDTILFKLETVEERDRKHQQDSDLSVQMLKDFLEDG-DTDEYLLPPKLLLRYALLLDIVKPTSRRSMCFTKGYGSYIEGTGSVLQAAEDAQIENIYKSLPDLPP------------EEKIAKLSMLKLRYFTPKEIANLQGFPPEFGFPEKTTVKQRYRLLGNSLNVHVVAKLLTVLCEGFGNASESCHKMPLILDSNSKILS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14717-1", "uniprot_id": "TRDMT_HUMAN", "id": "O14717-1", "name": "tRNA (cytosine(38)-C(5))-methyltransferase", "aln": "MEPLRVLELYSGVGGMHHALRESCIPAQVVAAIDVNTVANEVYKYNFPHTQLLAKTIEGITLEEFDRLSFDMILMSPPCQPFTRIGRQGDMTDSRTNSFLHILDILPRLQKLPKYILLENVKGFEVSSTRDLLIQTIENCGFQYQEFLLSPTSLGIPNSRLRYFLIAKLQSEPLPFQAPGQVLMEFPKIESVHPQKYAMDVENKIQEKNVEPNISFDG-SIQCSGKDAILFKLETAEEIHRKNQQDSDLSVKMLKDFLEDDTDVNQYLLPPKSLLRYALLLDIVQPTCRRSVCFTKGYGSYIEGTGSVLQTAEDVQVENIYKSLTNLSQ------------EEQITKLLILKLRYFTPKEIANLLGFPPEFGFPEKITVKQRYRLLGNSLNVHVVAKLIKILYE------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VKB3-1", "uniprot_id": "Q9VKB3_DROME", "id": "Q9VKB3-1", "name": "tRNA (cytosine(38)-C(5))-methyltransferase", "aln": "-MVFRVLELFSGIGGMHYAFNYAQLDGQIVAALDVNTVANAVYAHNYGSNLVKTRNIQSLSVKEVTKLQANMLLMSPPCQPHTRQGLQRDTEDKRSDALTHLCGLIPECQEL-EYILMENVKGFESSQARNQFIESLERSGFHWREFILTPTQFNVPNTRYRYYCIARKGAD-FPFAG-GKIWEEMPG---AIAQNQGLSQIAEIVEENVSP-----------------------------------------------------DFLVPDDVLTKRVLVMDIIHPAQSRSMCFTKGYTHYTEGTGSAYTPLSEDESHRIFELVKEIDTSNQDASKSEKILQQRLDLLHQVRLRYFTPREVARLMSFPENFEFPPETTNRQKYRLLGNSINVKVVGELIKLLTIK-----------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*****:**:****:*:. : : .::***:**.**** ** :*: . : ::.*:.:::::. :*. :*:********.** * * * * *: :: :: .::*. *:* :***:******* *.:*. :*:::* .**:::**:*:*:.:.:**:* **: **: :: : * . *:: *:* . .*: .: : . * ::*:* . * : .*::**::*: **:****** * *****. . .: : ..*:: : :: :::: * ::******:*:*.* .** :* ** : * :*:*******:**:**.:*:.:* ", "identical_positions": 130, "similar_positions": 125, "identity": "30.37%" }, { "cls_id": "homologset.agr.MGI:1274789", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9EQS0-1", "uniprot_id": "TALDO_RAT", "id": "Q9EQS0-1", "name": "Transaldolase", "aln": "MSGSPVKRQRMES-ALDQLKQF-TTVVADTGDFNAIDEYKPQDATTNPSLILAAAQMPAYQELVEEAIAYGKKLGGPQEEQIKNAIDKLFVLFGAEILKKIPGRVSTEVDARLSFDKDAMVARARRIIELYKEAGISKDRILIKLSSTWEGIQAGKELEEQHGIHCNMTLLFSFAQAVACAEAGVTLISPFVGRILDWHVANTDKKSYEPQEDPGVKSVTKIYNYYKKFGYKTIVMGASFRNTGEIKALAGCDFLTISPKLLGELLKDSSKLAPTLSVKAAQTSDLEKIH--LDEKAFRWLHNEDQMAVEKLSDGIRKFAADAIKLERMLTERMFSAENGK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q93092-1", "uniprot_id": "TALDO_MOUSE", "id": "Q93092-1", "name": "Transaldolase", "aln": "MSGSPVKRQRMES-ALDQLKQF-TTVVADTGDFNAIDEYKPQDATTNPSLILAAAQMPAYQELVEEAIAYGKKLGGPQEEQIKNAIDKLFVLFGAEILKKIPGRVSTEVDARLSFDKDAMVARARRLIELYKEAGVGKDRILIKLSSTWEGIQAGKELEEQHGIHCNMTLLFSFAQAVACAEAGVTLISPFVGRILDWHVANTDKKSYEPQEDPGVKSVTKIYNYYKKFGYKTIVMGASFRNTGEIKALAGCDFLTISPKLLGELLKDNSKLAPALSVKAAQTSDSEKIH--LDEKAFRWLHNEDQMAVEKLSDGIRKFAADAIKLERMLTERMFSAENGK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P37837-1", "uniprot_id": "TALDO_HUMAN", "id": "P37837-1", "name": "Transaldolase", "aln": "MSSSPVKRQRMES-ALDQLKQF-TTVVADTGDFHAIDEYKPQDATTNPSLILAAAQMPAYQELVEEAIAYGRKLGGSQEDQIKNAIDKLFVLFGAEILKKIPGRVSTEVDARLSFDKDAMVARARRLIELYKEAGISKDRILIKLSSTWEGIQAGKELEEQHGIHCNMTLLFSFAQAVACAEAGVTLISPFVGRILDWHVANTDKKSYEPLEDPGVKSVTKIYNYYKKFSYKTIVMGASFRNTGEIKALAGCDFLTISPKLLGELLQDNAKLVPVLSAKAAQASDLEKIH--LDEKSFRWLHNEDQMAVEKLSDGIRKFAADAVKLERMLTERMFNAENGK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W1G0-1", "uniprot_id": "TALDO_DROME", "id": "Q9W1G0-1", "name": "Probable transaldolase", "aln": "MGSDRTLKKQKMS-VLQELKKI-TTIVADTGDFEAINIYKPTDATTNPSLILSASSMERYQPLVQKAVEYAKGKKGSVSEQVAEAMDYLCVLFGTEILKVVPGRVSTEIDARLSFDTKKSVEKALKLIALYKSLGVDKERILIKLASTWEGIKAAEILENEHGVHCNLTLLFSFAQAVACAEAGVTLISPFVGRILDWYVANTDTKKFEALKDPGVISVTNIYNYYKKFGYKTLVMGASFRNVGEIKALAGCDLLTISPALLKELENETESVVTYLSVSNAKLQDIEKIT--VDESRFRWLLNEDAMATDKLSEGIRKFAVDTVKLENLIKTYLK------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53228-1", "uniprot_id": "TAL2_YEAST", "id": "P53228-1", "name": "Transaldolase NQM1", "aln": "MSEPSEKKQKVATSSLEQLKKAGTHVVADSGDFEAISKYEPQDSTTNPSLILAASKLEKYARFIDAAVEYGRKHGKTDHEKIENAMDKILVEFGTQILKVVPGRVSTEVDARLSFDKKATVKKALHIIKLYKDAGVPKERVLIKIASTWEGIQAARELEVKHGIHCNMTLLFSFTQAVACAEANVTLISPFVGRIMDFYKALSG-KDYTAETDPGVLSVKKIYSYYKRHGYATEVMAASFRNLDELKALAGIDNMTLPLNLLEQLYESTDPIENKLNSESAKEEGVEKVSFINDEPHFRYVLNEDQMATEKLSDGIRKFSADIEALYKLVEEKM-------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P15019-1", "uniprot_id": "TAL1_YEAST", "id": "P15019-1", "name": "Transaldolase", "aln": "MSEPAQKKQKVANNSLEQLKASGTVVVADTGDFGSIAKFQPQDSTTNPSLILAAAKQPTYAKLIDVAVEYGKKHGKTTEEQVENAVDRLLVEFGKEILKIVPGRVSTEVDARLSFDTQATIEKARHIIKLFEQEGVSKERVLIKIASTWEGIQAAKELEEKDGIHCNLTLLFSFVQAVACAEAQVTLISPFVGRILDWYKSSTG-KDYKGEADPGVISVKKIYNYYKKYGYKTIVMGASFRSTDEIKNLAGVDYLTISPALLDKLMNSTEPFPRVLDPVSAKKEAGDKISYISDESKFRFDLNEDAMATEKLSEGIRKFSADIVTLFDLIEKKVTA-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. ::: . *::** * :***:*** :* ::* *:********:*:. * ::: *: *.: . ::: :*:* : * ** :*** :*******:*******.. : :* ::* *::. *: *:*:***::******:*.. ** :.*:***:******.******** ***********:*:: : :. *.: **** **.:**.***:..* * **.****. .*:* *** * :*:. ** :* :.. . *. *: . :*: ** **: *** **.:***:*****:.* * :: : ", "identical_positions": 148, "similar_positions": 94, "identity": "43.4%" }, { "cls_id": "homologset.agr.MGI:1274790", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P55249-1", "uniprot_id": "LX12E_MOUSE", "id": "P55249-1", "name": "Polyunsaturated fatty acid (12S)/(13S)-lipoxygenase, epidermal-type", "aln": "MVKYKILVATGDSVFAGSANLVHLWLVGEHGEADLGKQLRPLLGRKTELEVDVPLHLGRLLAVKLRKQKGLLDSDWFCKSITVQGPGTQGEAFFPCYSWVQGKETICLTEGTALKVTDDTQNLFRKYREQELENRRNVYRWGSWKEGLILPIAGSTERDLPRNQRFMKDKDLDFSLSLVKELKNFAIKGTLDFVSRVQKLEDYQKVFPHTKTALPERVRGSWKEDALFGYQFLNGANPMLLRRSMRLPARLVLPPGMEDVQTQLEKELKAGSLFEVDFSLLDGVKPNIIIFKQQYVTAPLVMLKLQPDGRLLPMVIQLQPPRHGCPPPLLFLPSDPPMAWLLAKIWVRSSDFQLHQLQSHLLRGHLMAEVISVATMRSLPSLHPIYKLLAPHFRYTMEINTLARNNLVSEWGIFDLVVSTGSGGHVDILQRATSCLTYRSFCPPDDLADRGLVGVKSSLYAQDALRLWEIISRYVERMVELFYRSDTDVKEDPELQVWCREVTEVGLLGAQDRGFPLSLESRAELCRFVAMCIFTCTGQHASTHLGQLDWYAWIPNGPCTMRKPPPISKDVTERDIVDSLPCLQQARMQITVTKFLGRRQPVMVALGQHKEEYFSGPRPRDVLKQFQEELAIMDKEIEVRNASLDLPYEYLRPSLVENSVTI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZQF9-1", "uniprot_id": "LX12E_RAT", "id": "D3ZQF9-1", "name": "Polyunsaturated fatty acid (12S)/(13S)-lipoxygenase, epidermal-type", "aln": "MGKYKILVVTGDSLLAGSTNLVQLWLVGEHAEADLGKQLRPLRGRKTELEIDVPLHLGRLLVVKLRKHKGLLDSDWFCKWITVQGPGIQGEAFFPCYSWVQGKETIYLPEGTALKVNDDTKNLFRKYREQELEDRRNVYRWGSWKEGLILPIAGSTERDLPRNQRFMEDKDLDFSLSLAKVLKDFAIKGTLDFVSRVQHLEDYQKVFPHSKTALAGRVRDSWKEDALFGYQFLNGANPMLLRRSKRLPARLVLPPGMEDLQTQLEKELKAGSLFEADFSLLDGVKPNVIIFKQQHVAAPLVMLKLQSDGRLLPMVIQLQPPRHGCPPPLLFLPSDPPMAWLLAKIWVRSSDFQVHQLQSHLLRGHLMAEVISVATMRSLPSLHPIYKLLAPHFRYTMEINTLARNNLVSEWGIFDLVVSTGSGGHVDILQRATACLTYRSFCPPDDLADRGLLDVKSSLYARDALRLWEIISRYVGRMVELFYKNDREVKEDPELQVWCREVTEIGLLGAQDRGFPLSLESRAQLCRFVTMCIFTCTGQHASTHLGQLDWYSWIPNGPCTMRKPPPTSKNVTEGDILDALPCLQQARMQITFTKFLGRHQPVMVALGQHKEEYFSDPGARAVLKQFQEELAVMDKEIEVRNASLDLPYEYLRPSMVENSVTI", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* ******.****::***:***:*******.*********** *******:**********.*****:*********** ******* ****************** *.*******.***:************:*********************************:**********.* **:**************:**********:****. ***.************************ **************:***************.***********:******:*:*********.**********************************************:*******************************************************************************:******************:.*******:************* *******:.* :****************:******************:*****:*********************:************** **:*** **:*:************.******:****************.* .* **********:**********************:*******", "identical_positions": 601, "similar_positions": 47, "identity": "90.79%" }, { "cls_id": "homologset.agr.MGI:1276102", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O60306-1", "uniprot_id": "AQR_HUMAN", "id": "O60306-1", "name": "RNA helicase aquarius", "aln": "-----------MAAPAQPKK--IVAPTVSQINAEFVTQLACKYWAPHIKK-KSPFDIKVIEDIYEKEIVKSR-FAIRKIMLLEFSQYLENYLWMNYSPEVSSKAYLMSICCMVNEKFRENVPAWEIFKKKPDHFPFFFKHILKAALAET---DGEFSLHEQTVLLLFLDHCFNSLEVDLIRSQVQQLISLPMWMGLQLARLELELKKTPKLRKFWNLIKKNDEKMDPEAREQAYQERRFLSQLIQKFISVLKSVPLSEPVTMDKVHYCERFIELMIDLEALLPTRRWFNTILDDSHLLVHCYLSNLVRREEDGHLFSQLLDMLKFYTGFEINDQTGNALTENEMTTIHYDRITSLQRAAFAHFPELYDFALSNVAEVDTRESLVKFFGPLSSNTLHQVASYLCLLPTLPKN--EDTTFDKEFLLELLVSRHERRISQIQQLNQMPLYPTEKIIWDENIVPTEYYSGEGCLALPKLNLQFLTLHDYLLRNFNLFRLESTYEIRQDIEDSVSRMKPWQSEYGGVVFGGWARMAQPIVAFTVVEVAKPNIGENWPTRVRADVTINLNVRDHIKDEWEGLRKHDVCFLITVRPTKPYGTKFDRRRPFIEQVGLVYVRGCEIQGMLDDKGRVIEDGPEPRPNLRGESRTFRVFLDPNQYQQDMTNTIQNGAEDVYETFNIIMRRKPKENNFKAVLETIRNLMNTDCVVPDWLHDIILGYGDPSSAHYSKMPNQIATLDFNDTFLSIEHLKASFPGHNVKVTVEDPALQIPPFRITFPVRSGKGKKRKDADVEDEDTEEAKTLIVEPHVIPNRGPYPYNQPKRNTIQFTHTQIEAIRAGMQPGLTMVVGPPGTGKTDVAVQIISNIYHNFPEQRTLIVTHSNQALNQLFEKIMALDIDERHLLRLGHGEEELETEKDFSRYGRVNYVLARRIELLEEVKRLQKSLGVPGDASYTCETAGYFFLYQVMSRWEEYISKVKNKGSTLPDVT----EVSTFFPFHEYFANAPQPIFKGRSYEEDMEIAEGCFRHIKKIFTQLEEFRASELLRSGLDRSKYLLVKEAKIIAMTCTHAALKRHDLVKLGFKYDNILMEEAAQILEIETFIPLLLQNPQDGFSRLKRWIMIGDHHQLPPVIKNMAFQKYSNMEQSLFTRFVRVGVPTVDLDAQGRARASLCNLYNWRYKNLGNLPHVQLLPEFSTANAGLLYDFQLINVEDFQGVGESEPNPYFYQNLGEAEYVVALFMYMCLLGYPADKISILTTYNGQKHLIRDIINRRCGNNPLIGRPNKVTTVDRFQGQQNDYILLSLVRTRAVGHLRDVRRLVVAMSRARLGLYIFARVSLFQNCFELTPAFSQLTARPLHLHIIPTEPFPTTRKN-GERPSHEVQIIKNMPQMANFVYNMYMHLIQTTHHYHQTLLQLPPAMVEEGEEVQNQETELETEEEAMTVQADIIPSPTDTSCRQETPAFQTDTTPSETGATSTPEAIPALSETTPTVVGAVSAPAEANTPQDATSAPEETK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8CFQ3-1", "uniprot_id": "AQR_MOUSE", "id": "Q8CFQ3-1", "name": "RNA helicase aquarius", "aln": "-----------MAAPAQPKK--IVAPTVSQINAEFVTQLACKYWAPHIKK-KSPFDIKVIEEIYEKEIVKSR-FAIRKIMLLEFSQYLENYLWMNYSPEVSSKAYLMSICCMVNEKFRENVPAWETFKKKPDHFPFFFKCILKAALAET---DGEFSLHEQTLLLLFLDHCFNSLEVDLIRSQVQQLISLPMWMGLQPARLELELKKTPKLRKFWNLIKKNDEKMDPEAREQAYQERRFLSRLIQKFISVLKSIPLSEPVTMDKVHYCERFIELMIDLEALLPTRRWFNTILDDSHLLVHCYLSSLVHREEDGHLFSQLLDMLKFYTGFEINDQTGNALTENEMTTIHYDRITSLQRAAFAHFPELYDFALSNVAEVDARDSLVKFFGPLSSNTLHQVASYLCLLPTLPKN--EDTTFDKEFLLELLVSRHERRISQIQQLNQMPLYPTEKIIWDENIVPTEYYSGEGCLALPKLNLQFLTLHDYLLRNFNLFRLESTYEIRQDIEDSVSRMKPWQSEYGGVVFGGWARMAQPIVAFTVVEVAKPNIGENWPTRVRADVTINLNVRDHIKDEWEGLRKHDVCFLITVRPTKPYGTKFDRRRPFIEQVGLVYVRGCEIQGMLDDKGRVIEDGPEPRPNLRGESRTFRVFLDPNQYQQDMTNTIQNGAEDVYDTFNVIMRRKPKENNFKAVLETIRNLMNTDCVVPDWLHDIILGYGDPSSAHYSKMPNQIATLDFNDTFLSIEHLKASFPGHNVKVTVSDPALQIPPFRITFPVRSGKGKKRKDADGEEDDTEEAKTLIVEPHVIPNRGPYPYNQPKRNTIQFTHTQIEAIRAGMQPGLTMVVGPPGTGKTDVAVQIISNIYHNFPEQRTLIVTHSNQALNQLFEKIMALDIDERHLLRLGHGEEELETEKDFSRYGRVNYVLARRIELLEEVKRLQKSLGVPGDASYTCETAGYFFLYQVMSRWEEYMSRVKNSGTACPDAAPDAAQVATFFPFHEYFANAPQPIFKGRSYEEDMEIAEGCFRHIKKIFTQLEEFRASELLRSGLDRSKYLLVKEAKIIAMTCTHAALKRHDLVKLGFKYDNILMEEAAQILEIETFIPLLLQNPQDGFSRLKRWIMIGDHHQLPPVIKNMAFQKYSNMEQSLFTRFVRVGVPTVDLDAQGRARASLCNLYNWRYKNLGNLPHVQLLPEFSTANAGLLYDFQLINVEDFQGVGESEPNPYFYQNLGEAEYVVALFMYMCLLGYPADKISILTTYNGQKHLIRDIINRRCGNNPLIGRPNKVTTVDRFQGQQNDYILLSLVRTRAVGHLRDVRRLVVAMSRARLGLYIFARVSLFQNCFELTPAFSQLTARPLHLHIIPTEPFPTSRKN-GERPPHEVQVIKNMPQMANFVYNMYMHLIQTTHHYHQTFLQLPPAMVEEGEEGQSQETEMEAEEETVSAQGNLTPSPADASLSQETPAAQPDCS-SQTEDTSAPCDIATAAEP-------VSAAAEAATPQDAESVPTETE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7KSN8-1", "uniprot_id": "Q7KSN8_DROME", "id": "Q7KSN8-1", "name": "RNA helicase aquarius", "aln": "MKRRSQTRAEQAVPPAKTTKENSGSLTVSQLSSDVIWQLASQYWTPDTKADHLPYSAKIIERIYNEEIGDGGGHSARRINMLEFSQYLEQYLWPHYQRETATHAHLMSIVIMANEKFRERVEVWTVFEKLPDQYPAFFRHVLESCLPSKKAKEASSTLRERTALLMFINHCFNSMEIELCREQAKRLVSLSMWHCLQPRRREQELREVPEWRKYWKRLLKKEK----DSKPEVLWERHFMQNLIIDFLHILESIPAEGEVPRNVVHYCERFLEFIIDLEALLPTRRFFNTVLDDCHLIVRALLSPLVRREE-GKLFGQLLDMLKFYTRFEINDVTGSSLTDHDMTQLHYKKITSLQRAVFAKFPSLRVFALSNVATVDNRESLEQHFGGLDGKGLLQIATFLNLVPEEVVSPLDWHRVDEQFLRELLITRHERRCSQLEALNEMPLYPTEQIIWDENVVPSEYYSGDSCLALPKLNLQFLTLHDYLLRNFNLFRLESTYEIRQDIEDAVSRMLPWKSEDGDVVFGGWARMALPIASFAVVEVAKPHLGEKKPSRVRADVGVTLSVRREIKAEWENLRKHDVCFLITVKPTQPYGTKYKHREPFVPQVGLVSVRGCEVEGMLDANGRVIEDGPEPRPQLQGENRCYRVWLDSNQYRLDMD-DLQEGADDVYESFNILMRRKPKENNFKAVLETIRHLMNTECVVPPWLHDILLGYGDPGAAHYSNMPNQERSLEFNDTFMDYNHLEASFPQYNLKCEVPVENRQ-PPFRLIFEDVPIQKESDGEDPEEKPEEKLTKSILVQPYKYEARGPYPSDKPKQNSIRFTPTQVEAIRAGMQPGLTLVVGPPGTGKTDVAVQIISNIYHNHPNQRTLIVTHSNQALNQLFEKIMALDIDERHLLRLGHGEEALETEKDYSRYGRVNYVLAKRMDLLSQVQKLQEALGVSGDNAYTCETAGYFYLYNVMARWEKFQSQIS-VHKGEADAEKLRAEFEKEFPFGKFFADAPQPLFKGANYDELMDIACSNFRYISDIFNELEEFRAFELLRTGLDRSKYLLVKEAKIIAMTCTHAALKRKELVNLGFRYDNILMEESAQILEIETFIPLLLQNPLDGLNRLKRWIMIGDHHQLPPVIKNMAFQKYSNMEQSLFTRLVRLGVPTVDLDGQGRARASICSLYKWRYKKLEDLQHIFERDEYKQANPGFVHDYQLINVEDFKGVGESEPNPYFYQNLAEAEYIVAVYMYMRLLGYPAAKISILTTYNGQKHLIRDVINARCGNNPLIGWPHKITTVDKYQGQQNDYILISLVRTKAVGHLRDVRRLVVAMSRARLGLYVFGRVSLFKNCLELQQTFKLLTQRPLKLSLVPEDKFPTDRLASAAVASQDIKTVENMSEMAQFVYERYMAKMEELKGTLPSEEELEAMRNQLLQE--DEESVPEASEEPPEKRAAKEEP---LSKKKTTEAFKPTPILNEINVDDTEMGQREQIEE-----------EATDQDKTQESAPAEES", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ..**:..* : ****:.::.: ***.:**:*. * : *:. *:** **::** .. .: *:* :********:*** :*. *.:::*:**** *.******.* .* *:* **::* **: :*::.*... :.. :*:*:* **:*::*****:*::* *.*.::*:**.** ** * * **::.*: **:*: : *::: ::: :. **:*:..** .*: :*:*:* . *. : *******:*::***********:***:***.**:*:. ** **:*** *:**.********** ***** **.:**:::** :**.:*******.**:**.* ******* ** *:** :.** *..: * *:*::* *:* . : .*::** ***::***** **:: **:*******:******:**:*****:.***************************************:**** **:** *.********** **.:*:*******::**: *:****** :.*.** .** ***.************:**:*****:.:*.**: ***** *****::**** :************:*:**.* :**:**.***: ** :*:**:***::**::******************:****:**** *****:******.:****:**** :*:*****:. :**:**** :*:* * * ****: * . : :. : *. : : :*:::*:*: ***** ::**:*:*:** **:************:***********************.*:************************************** ******:***********:*::**.:*::**::***.** :*********:**:**:***:: *::. . .*. :. . *** ::**:****:*** .*:* *:** . **:*..**.:****** ****:***************************::**:***:********:***************** **:.************************************:**:********.*******:*.**:****:* :* *: *:. **.*:::*:********:***************.****:**::*** ****** *****************:** ********* *:*:****::*********:*****:***********************:*.*****:**:** :*. ** ***:* ::* : *** * . ..:::: ::**.:**:***: ** :: : : :* . : :* .:*: *:.**. :. . * : * * :. .: .: * : : *.* * .", "identical_positions": 899, "similar_positions": 346, "identity": "59.54%" }, { "cls_id": "homologset.agr.MGI:1276106", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88874-1", "uniprot_id": "CCNK_MOUSE", "id": "O88874-1", "name": "Cyclin-K", "aln": "MKENKENSSPSVT--SANLDHTKPCWYWDKKDLAHTPSQLEGLDPATEARYRREGARFIFDVGTRLGLHYDTLATGIIYFHRFYMFHSFKQFPRYVTGACCLFLAGKVEETPKKCKDIIKTARSLLNDVQFGQFGDDPKEEVMVLERILLQTIKFDLQVEHPYQFLLKYAKQLKGDKNKIQKLVQMAWTFVNDSLCTTLSLQWEPEIIAVAVMYLAGRLCKFEIQEWTSKPMYRRWWEQFVQDVPVDVLEDICHQILDLYSQGKQQMPHHTPHQLQQPPSLQPTPQVPQGPQSQPSQGSEAAQPPQKDSQQSAQQQQQQAQQPKKPSPQPSPPRQAKRAVVVSPKEENKATEPPPPPKIPKLEATHPPLPPAHPPPDRKPPLAPALGEAEATGPVETSDLPKVQIPPPAHPAPVHQPPPLPHRPPP----PPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALP----------------------------PASFPPPTIPPPTPGYPPPPPTYNPNFPPPPPRLPPTHAVPPHPPPGLGLPPASYPPPAVPPGGQPPVPPPIPPPGMPPVGGLGRAAWMR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75909-3", "uniprot_id": "CCNK_HUMAN", "id": "O75909-3", "name": "Cyclin-K", "aln": "MKENKENSSPSVT--SANLDHTKPCWYWDKKDLAHTPSQLEGLDPATEARYRREGARFIFDVGTRLGLHYDTLATGIIYFHRFYMFHSFKQFPRYVTGACCLFLAGKVEETPKKCKDIIKTARSLLNDVQFGQFGDDPKEEVMVLERILLQTIKFDLQVEHPYQFLLKYAKQLKGDKNKIQKLVQMAWTFVNDSLCTTLSLQWEPEIIAVAVMYLAGRLCKFEIQEWTSKPMYRRWWEQFVQDVPVDVLEDICHQILDLYSQGKQQMPHHTPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQP-AQQPKKPSPQPSSPRQVKRAVVVSPKEENKAAEPPPP-KIPKIETTHPPLPPAHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAPVHQPPPLPHRPPP----PPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPNPPPPPVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPPPPRLPPTHAVPPHPPPGLGLPPASYPPPAVPPGGQPPVPPPIPPPGMPPVGGLGRAAWMR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QMB9-1", "uniprot_id": "CCNK_DANRE", "id": "F1QMB9-1", "name": "Cyclin-K", "aln": "MKDGKENSNATFGSFTTNLDHTKPCWYWDKKDLAHTPSQSD-LDPATEARYRREGARFIFDVGTRLGLHYDTLATGITYFHRFYMFHSFKQFPRYVTGACCLFLAGKVEETPKKCKDIIKTARSLLNDVQFAQFGDDPKEEVMVLERILLQTIKFDLQVEHPYQFLLRYAKQLKGDKNKVQKLVQMAWTFVNDSLCTMLSLQWEPEIIAVAVMYLAGRLCKFDIQEWTSKQSSRRWWEQFVQDVPVELLEDICHQILDLYSQGKQPIPQQPPMQDKEKP-----PPPPAAPPGQSGAQNPPAQPP-----------------SKKNSPQASPPAKIKR-QHVSPKDEPKAPAEQVGSKIPRLESPMPPLPVSQPP-ERKTPSAIPAPPAEA-EPAAASELDPAQG--PAPPLPHGAPPPLPHRPPPTEFGGPCSDFLSSVKHKRRYLDDD--RNL-------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:.****..:. ::********************** : *********************************** *****************************************************.***********************************:***********:***************** ************************:******* *************::***************** :*::.* * :: * * * .*.. . .:** .** ***.*.* : ** ****:* **. ***::*:. **** ::** :**.* * . **. *. :::* .* ** * * ********** * *.:::.:. . *:..: :.* ", "identical_positions": 302, "similar_positions": 62, "identity": "51.36%" }, { "cls_id": "homologset.agr.MGI:1276107", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35548-1", "uniprot_id": "MMP16_RAT", "id": "O35548-1", "name": "Matrix metalloproteinase-16", "aln": "MILLAFSSGRRLDFVHRSGVFFFQTLLWILCATVCGTEQYFNVEV-------WLQKYGYLPP--TDPRMSVLRSAETMQSALAAMQQFYGINMTGKVDRNTIDWMKKPRCGVPDQTRGSSK----------FNIRRKRYALTGQKWQHKHITYSIKNVTPKVGDPETRRAIRRAFDVWQNVTPLTFEEVPYSELENGKRDVDITIIFASGFHGDRSPFDGEGGFLAHAYFPGPGIGGDTHFDSDEPWTLGNPNHDG-----NDLFLVAVHELGHALGLEHSNDPTAIMAPFYQYMETDNFKLPNDDLQGIQKIYGPPDKIPPPTRPLPTVPPHRSV-----------------------------------------------------------------------------------------------------------------------------------------------------------PPADPRKNDRPKPPRPP--------TGRPSYPGAKPNICDGNFNTLAILRREMFVFKDQWFWRVRNNRVMDGYPMQITYFWRGLPP---SIDAVYENSDGNFVFFKGNKYWVFKDTTLQPGYPHDLITLGNGIPPHGIDSAIWWEDVGKTYFFKGDRYWRYSEEMKT-MDPGYPKPITIWKGIPESPQGAFVHKENGFTYFYKGKEYWKFNNQILKVEPG---YPRSILKDFMGCDGPTDRD------KEGLSPP----------DDVDIVIKLDNTASTVKAIAIVIPCILALCLLVLVYTVFQFKRKGTPRHILYCKRSMQEWV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WTR0-1", "uniprot_id": "MMP16_MOUSE", "id": "Q9WTR0-1", "name": "Matrix metalloproteinase-16", "aln": "MILLAFSSGRRLDFVHRSGVFFLQTLLWILCATVCGTEQYFNVEV-------WLQKYGYLPP--TDPRMSVLRSAETMQSALAAMQQFYGINMTGKVDRNTIDWMKKPRCGVPDQTRGSSK----------FNIRRKRYALTGQKWQHKHITYSIKNVTPKVGDPETRRAIRRAFDVWQNVTPLTFEEVPYSELENGKRDVDITIIFASGFHGDSSPFDGEGGFLAHAYFPGPGIGGDTHFDSDEPWTLGNPNHDG-----NDLFLVAVHELGHALGLEHSNDPTAIMAPFYQYMETDNFKLPNDDLQGIQKIYGPPDKIPPPTRPLPTVPPHRSV-----------------------------------------------------------------------------------------------------------------------------------------------------------PPADPRRHDRPKPPRPP--------TGRPSYPGAKPNICDGNFNTLAILRREMFVFKDQWFWRVRNNRVMDGYPMQITYFWRGLPP---SIDAVYENSDGNFVFFKGNKYWVFKDTTLQPGYPHDLITLGNGIPPHGIDSAIWWEDVGKTYFFKGDRYWRYSEEMKT-MDPGYPKPITIWKGIPESPQGAFVHKENGFTYFYKGKEYWKFNNQILKVEPG---YPRSILKDFMGCDGPTDRD------KEGLSPP----------DDVDIVIKLDNTASTVKAIAIVIPCILALCLLVLVYTVFQFKRKGTPRHILYCKRSMQEWV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P51512-1", "uniprot_id": "MMP16_HUMAN", "id": "P51512-1", "name": "Matrix metalloproteinase-16", "aln": "MILLTFSTGRRLDFVHHSGVFFLQTLLWILCATVCGTEQYFNVEV-------WLQKYGYLPP--TDPRMSVLRSAETMQSALAAMQQFYGINMTGKVDRNTIDWMKKPRCGVPDQTRGSSK----------FHIRRKRYALTGQKWQHKHITYSIKNVTPKVGDPETRKAIRRAFDVWQNVTPLTFEEVPYSELENGKRDVDITIIFASGFHGDSSPFDGEGGFLAHAYFPGPGIGGDTHFDSDEPWTLGNPNHDG-----NDLFLVAVHELGHALGLEHSNDPTAIMAPFYQYMETDNFKLPNDDLQGIQKIYGPPDKIPPPTRPLPTVPPHRSI-----------------------------------------------------------------------------------------------------------------------------------------------------------PPADPRKNDRPKPPRPP--------TGRPSYPGAKPNICDGNFNTLAILRREMFVFKDQWFWRVRNNRVMDGYPMQITYFWRGLPP---SIDAVYENSDGNFVFFKGNKYWVFKDTTLQPGYPHDLITLGSGIPPHGIDSAIWWEDVGKTYFFKGDRYWRYSEEMKT-MDPGYPKPITVWKGIPESPQGAFVHKENGFTYFYKGKEYWKFNNQILKVEPG---YPRSILKDFMGCDGPTDRV------KEGHSPP----------DDVDIVIKLDNTASTVKAIAIVIPCILALCLLVLVYTVFQFKRKGTPRHILYCKRSMQEWV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1R8N4-1", "uniprot_id": "F1R8N4_DANRE", "id": "F1R8N4-1", "name": "", "aln": "-MNVTLLKRRRLDCVY-ALLFWLHNAMWMCRS--AAEEHQFSVEV-------WLQKYGYLHP--TPPNMAAQRSAQTMHSAIAAMQHKYGLNITGTLNKYTIDWMKKPRCGVPDQLKAGS-----------ASRRKKRYALTGQKWQREHISYSIKNVTPKVGNQETHDAIRRAFDVWQGVTPLRFEAVPFRDLDSGKRDVDITIIFASGFHGDSSPFDGEGGFLAHAYFPGPGIGGDTHFDSDEPWTLGNPNHDGERTAGNDLFLVAVHELGHALGLEHSSDPTAIMAPFYQYMDTESFKLPHDDLQGIQKIYGPPNKNPQPTRLLTTATPPRLH-----------------------------------------------------------------------------------------------------------------------------------------------------------LPSDPRKHERSRPHRPPQ-------KNKPSHPNSKPDICDGGFNTLAILRNELFVFKDQWFWRVRDNSVVPGYPMQISYFWRGLPP---KIDAVYENSEGKFVFFKGNRFWVFKDTTLQPTYPQDISLFGSGMPTQSIETAVWWEDVAKTYFFKGDRYWRYNEDMRT-MDPGYPQPITVWKGIPDSPQGAFVDKANGFTYFYKGKEYWKFNNQRLRVEPG---YPRSILRDFMGCDGLPTDP------DWDWSPPQEEEPPQFDDDNVDIVLKLESSGGAEKAVAIAIPCVLALCMMVLLYTVFRFKRKDTQRHILYCKRSMQEWV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W122-1", "uniprot_id": "Q9W122_DROME", "id": "Q9W122-1", "name": "", "aln": "----------MTNCQSSVFIVVGTLFSIMAAAQSAPVSTTTQAEI-------YLSQFGYLPASARNPASSGLHDQRTWVSAIEEFQSFAGLNITGELDAETMKLMSLPRCGVRDRVGTGD-------------SRSKRYALQGSRWRVKNLTYKISKYPKRLKRVDVDAEIGRAFAVWSEDTDLTFTRKTS-------GPVHIEIKFVESEHGDGDAFDGQGGTLAHAFFP--VFGGDAHFDDAELWTIGSPRGTN-------LFQVAAHEFGHSLGLSHSDQSSALMAPFYRGFEP-VFKLDEDDKAAIQSLYGRKTNQLRPTNVYPATTQRPYS-----------------------------------------------------------------------------------------------------------------------------------------------------------PPKVPLDDSICKDSKVD--------------------------TLFNSAQGETYAFKGDKYYKLTTDSVEEGYPQLISKGWPGLPG---NIDAAFTYKNGKTYFFKGTQYWRYQGRQMDGVYPKEISEGFTGIPDH-LDAAMVWGGNGKIYFFKGSKFWRFDPAKRPPVKASYPKPISNWEGVPNN-LDAALKYTNGYTYFFKGDKYYRFHDARFAVDSATPPFPRPTAHWWFGCKNTPSSTGNIVEGSDNEFEQHSMIPHADDGNGDDFDAAVGDHQSNDEPIVPEVAERTGNGAMSQSKLTSSSAVSTVITTILMCLVSKLIVS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8MPP3-1", "uniprot_id": "D2MP_DROME", "id": "Q8MPP3-1", "name": "Matrix metalloproteinase-2", "aln": "MFSKYVLATLLALFAQSMCIQELSLPPEGSHSTAATRSKKAKTAISEDIMYNYLMQFDYLPK--SDLETGALRTEDQLKEAIRSLQSFGNITVTGEIDSATARLIQKPRCGVGDRRSADSFSPDNLYHEIGSNVRVRRFALQGPKWSRTDLTWSMVNRS-MPDASKVERMVQTALDVWANHSKLTFREVYS-------DQADIQILFARRAHGDGYKFDGPGQVLAHAFYPGEGRGGDAHFDADETWNFDGESDDSHG---TNFLNVALHELGHSLGLAHSAIPDAVMFPWYQ-NNEVAGNLPDDDRYGIQQLYGTKEKTWGPYKPQTTTTTTTTTTMRAMIYRADKPAYWPWNNPSNNPNNDRNRARERQEEERRRQEKERRRQEEERRHQEEERRRQVEERQRQEEERWRQEQERQEEENRRRKIEHKSQWERNPSKERNRPRERQEMERRRQEQERQEQERQEQEDRRRERERDRQLEWERRNRNGAREPVTPTANTTPRPTNKPYPTVHRQHHHHNKPRKPKPDSCMTYYDAISIIRGELFIFRGPYLWRIGTSGLYNGYPTEIRRHWSALPENLTKVDAVYENKQRQIVFFIGREYYVFNSVMLAPGFPKPLASLGLPPTLTHIDASFVWGHNNRTYMTSGTLYWRIDDYTGQ-VELDYPRDMSIWSGVGYN-IDAAFQYLDGKTYFFKNLGYWEFNDDRMKVAHAR---AKLSARRWMQCARSANEVD----------------------DEQRWTASLVSEGEETGRSGSRELRINHFILSILLLAIANWRS------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . . .. : :* ::.** . : .*: :* .:.:** :: * :. ***** *: .. * :*:** * :* .:::.: : . .. : *: ** : * * ..* * *. *** *** * ****::* ***:*** * *.:.. . :: ** **:**:*** ** . *:* *:*: : :* .** .**.:** : * . .:.. * * . : . : : * : *:. ::: . : *** * * .** .:**.: .: : ** * .:: ::. : :*: : . ::::. * : *: .* :** . :. .**: :: *.*: . .* .. :* ***:*. *:.*:: : * . .: : :: * . : : . ", "identical_positions": 107, "similar_positions": 146, "identity": "13.1%" }, { "cls_id": "homologset.agr.MGI:1276108", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JZ53-1", "uniprot_id": "A0A0G2JZ53_RAT", "id": "A0A0G2JZ53-1", "name": "Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6", "aln": "MLRPLGSCPSFGAALFPLPRQPRSSLGLAGPAGDVPCACRRLTSLPANALRFAPWPRMVTGCGAAPPGTVTEPLPSVIVLSAGRKMAAAAAEASGPSCSSAAAAAGAGAAGVSEWLVLRDG-CMRCDADGLHSLSYHPALNAILAVTSRGTIKVIDGTSGATLQASALSAKPGGQVKCQYISAVDKVIFVDDYAVGCRKDLNGILLLDTALQTPVSKQDDVVQLELPVTEAQQLLSACVEKIDVSSTEGYDLFITQLKDGLKNTSHETAANHKVAKWATVTFHLPHHVLKSIASAIVNELKKINQNVAALPVASSVMDRLSYLLPSARPELGVGPGRSVDRALMYSEANRRETFTSWPHVGYRWAQPDPMAQAGFYHQPASSGDDRAMCFTCSVCLVCWEPTDEPWSEHERHSPNCPFVKGEHTQNVPLSVTLATSPAQLPSADGADRISCFGSGSCPQFLAAATKRGKICIWDVSKLMKVHLKFEINAYDPVIVQQLILSGDPS---SGVDSRRPTLAWLEDSSS----CSDIPKLEGDSDDLLEDSDSEEHSRSDSVTGHTSQKEAMEVSLDITALSILQQPEKLQWEIVANVLEDTVKDLEELGANP---CLTNSKSEKTKEKHQEQHNIPFPCLLAGGLLTYKSPATSPISSN-SHRSLDGLSRTQGES--ISEQGSTDNESCTN-SELNSP------LVRRTLPVLLLYSIKESDEK-AGKIFSQMNNIMSKSLHDDGFTVPQIIEMELDNQEQLLLQDPPVTYIQQFADAAASLTSPDSEKWNSVFPKPGTLVQCLRLPKFAEEETLCIDSITPCADGVHLLVGLRTCSVESLSAINQVEALNNLNKLNSALCNRRKGDLESN--LAVVNGANISVIQHESPADVPAPLIIQPEQRN-LSGGYLVLYKMNYTTRIVTLEEEPVKIQHIKDPQDTITSLILLPPDILDNREDDCEEPAEEMQLTSKN------------------GIEREKKSDVSTLGHLVVTTQGGYVKVLDLSNFEILAKVEPPKKEGTE-DQDTFVSVIYCSGTDRLCACTKGGELHFLQIGGTCDDIDEADILVDGSLSKGIEPSLEGSRPLSNPSSPGISGVDLLVDQPFTLEILTSLVELTRFETLTPRFSATVPPCWVEVQQEQQQRRHPQHLHQQHHGDAAQHTRTWKLQTDSNSWDEHVFELVLPKACMVGHVDFKFVLNSTITSVPQIQVSLLRNRAPGLGKANETAVDRQITFPLSPALNIEVEQNGNPSLVDLNEEMHPMDVEESQCLRLCPFLEDHKEDILCGPVWLASGLDLSGHAGMLTLTSPKLVKGMAGGKYRSFLIHIKAVSDRG-----------------------------------------------ADEVCSSGLRPVVRLPSLKQQGHKGYSLASLLAKVAAGKEKSSNVKNESAGGTRKSENLR-GCDLLQEVSVTIRRFKKTS-ICKERVQRCAMLQFSEFHEKLLNTLCRRSDDGLVTEHAQSLVLDTLCWLAGVHSNGPGSSKE--------------------GNECLLSKTRTCLSDIVRVCFFEAGRSIAHKCARFLALCISNGKCDPYQPG----FGSVLLKALLDNMCFLPAAATGGSVYWYFVLLNYVKDED-LAACSTACAALLTAVSRQLQDRLTPLEALLQTRYGLYSSPFDPVLFDLEMSGSSCKNVYNSSIGVQSDEIDLSDVLSGNGKVSS------------CTAAEGSFTSLTGLLEVEPLHFTCVSTSDGTRIERDDASTFTVSSFGVTPAVGGLSSGTVG--EASTALSSAAQVALQSLSHAMASAEQQLQVLQEKQQQLLKLQQQKAKLEAKLHQTTAAAAAAAS--AAAAAGPVHNAVPSNPVAAPGFFIHPSDVIPPTPKTTPLFMTPPLTPPN-EAVSVVINAELAQLFPGSVIDPPAVNLAAHNKNANKSRMNPLGSGLALAISHASHFLQPPPHQSIIIERMHSGARRFVTLDFGRPILLTDVLIPTCGDLASLSIDIWTLGEEVDGRRLVVATDISTHSLILHDLIPPPVCRFMKITVIGRYGSTNARAKIPLGFYYGHTYILPWESELKLMHDPLRGEGESANQPEIDQHLAMMVALQEDIQCRYNLACHRLEALLQSIDLPPLNSANNAQYFLRKPDK----AVEEDSRVFSAYQDCIQLQLQLNLAHNAVQRLKVAIGASRKTLSETSG-----PEDLIPTSSTEQLRTIVRYLLDTLLSLLHSSNGHSVPAVLQSTFHAQACEELFKHLCISGTPKIRLHTGLLLVQLCGGERWWGQFLSNVLQELYNSEQLLIFPQDRVFMLLSCIGQRSLSN----SGVLESLLNLLDNLLSPLQPELTMH------RRTEGVLDIPMISWVVMLVSRLLDYVATVEDEAAAAKKPLNGKDRERFLTGNQWSFINNNLHTQSLNRSSKGG-SSLDRLYSRKIRKQLVHHKQQLNLLKAKQKALVEQMEKEKIQSNKGSSYKLLVEQAKLKQATSKHFKDLIRLRRTAEWSRSNLDTEVTTTKESPEIEPLPFTLAHDRCISVVQKLVLFLLSMDFTCHADLLLFVCKVLARIANATRPTIHLCEIVNEPQLERLLLLLVGTDFNRGDISWGGAWAQYSLTCMLQDILAGELLAPVAAEAMEEGTVSDDVGATAG---DSDDSLQQ-SSVQLLETIDEPLTHEIAG-----------TPPLSSLEKDKEIDLELLQDLMEADIDPLDIDLEKDPLAAKVFKPISSTWYDYWGADYGTYNYNPYIGGLGMPVAKPPSNT--EKNGSQTVSVSVSQALDARLEVGLEQQAELMLKMMSTLEADSILQALTSTPPTFSQSPSGTDDSLLG-SLQPANQNSQLIIQLSSVPMLNVCFNKLFSMLQVHH--VQLESLLQLWLTLSLNSSSSGNKENGADIFLYNANRIPVISLNQASITSFLTVLAWYPNTLLRTWCLVLHSLTLMTNMQLNSGSSSSIGAQETTAHLLVSDPNLIHVLVKFLSGTSPHGTNQHSPQVGPTATQAMQEFLTRLQVHLSST---CPQIFSELLLKLIHILSTERGAFQTGQGPLDAQVKLLEFTLEQNFEVVSVSTISAVIESVTFLVHHYITCSDKVMSRSGSDSSVGARACFGGLFANLIRPGDAKAVCGEMTRDQLMFDLLKLVNILVQLPLSSNREYSARVSMTTNTTDSVSDEEKVSGGKDVNGS-NTSIPGSPAYVADLVLANQQIMSQILSALGLCNSSAMAMIIGASGLHLTKHENFHGGLDAISVGDGLFTILTTLSKKASTVHMMLQPILTYMACGYMGRQGSLATCQLSEPLLWFILRVLDTSDALKAFHDMGGVQLICNNMVTSTRAIVNTARSMVSTIMKFLDSGPNKAVDSTLKTRILASEPDN------------------AEGIHNFAPLGTITSSSPTAQPAEVLLQATP-PHRRARSAAWSYIFLPEEAWCDLTIHLPSAVLLKEIHIQPHLASLATCPSSVSVEVSADG-VNMLPLSTPVVTSGLTYIKIQLVKAEVASAVCLRLHRPRDASTLGLSQIKLLGLTAFG------------------------TTSSATVNNPFLPSEDQVSKTSIGWLRLLHHCLTHISD-----LEGMMASAAAPTANLLQTCAALL--MSPYCGMHSPNIEVVLVKIGLQSTRIGLKLIDILLRNCAASGSDPTDLNSPLLFGRLNGLSSDSTIDILYQLGTTQDPGTKDRIQALLKWVSDSAKMAALKRSGRMNYMCPSSS-AVEYGLLMPSPSHLHCVAAILWHSYELLVEYDLPALLDRELFELLFNWSMSLPCNVVLKKAVDSLLCSMCHIHPNYFSLLMGWMGIIPPP---VQCHHRLSMTDDSKKQ---DLSSSLTDDSKNAQA----PLALTESHLATLASSSQSPEAIKQLLDSGLPSLLVRSLASFCFSHISYSESIAQSIDNSQDKLR--------------------RHHVPQHCNKMPITADLVAPILRFLTEVGNSHIMKDWLGGSEVNPLWTALLFLLCHSGSTAGGHNLGAQQSS--------TRSASHSSAA---------------TTVLTTQQRTAIENATVAFFLQCISCHPNNQKLMAQVLCELFQTAPQRGSLPTSGNISGFVRRLFLQLMLEDEKVTMFLQSPCPLYKG-RINATSHVIQHPMFGAGHKFRTLHLPVSTTLSDVLDRVSDTPSITAKLISEQKDDKEKKNHEEKEKVKADNGFQDNYSVVVASGLKSQSKRAVSSTPPRPPSRRGRAIPDKIGSTSSSADTANKIITVPVFHLFHRLLAGQPLPAEMTLAQLLTLLYDRKLPQGYRSIDLTVKLGSKVITDPSLSKTDSFKRLHPEKDHGELIGSCPEDEALTPSDECMDGVLDESLLETCPIQSPLQVFAGMGGLALIAERLPMLYPEVIQQVSAPVVASTTQEKPKDSDQFEWVTIEQSGELVYEAPETIAAEPPPVKSAVQATSPIPAHSLAAFGLFLRLPGYAEVLLKERKHAQCLLRLVLGVTDDGEGSHILQSPSANVLPTLPFHVLRSLFSATPLTTDDGVLLRRMALEIGALHLILVCLSALSHHAPR---------------------------VPNSSLNQTEPQVSNSHNPTSTEEQQLYWAKGTGFGTGSTASGWDVEQALTKQRLEEEHVTCLLQVLASYINP---MSSAVNGEAQVSPESRAQNSSALPSVLLELLSQSCLIPAMSSYLRNDSVLDMARHVPLYRALLELLRAIASCTSMVPLLLPLSTENGEEEEE-EQSECQTSVGTLLAKMKTCVDTYTNRLRSKREN----IKTGVKPDAPDQEPEGLTLLVPDIQRTAEIVHAATTNLRQANQEKKLGEYSKKVAMKPKPLSVLKSLEEKYVAVMKTLQFDTFEMVSEDDDGKLGFKVNYHYMSQVKNANDANSAARARRLAQEAVTLSTSLPLSSSSSVFVRCDEERLDIMKVLITGPADTPYANGCFEFDVYFPQDYPSSPPLVNLETTGGHSVRFNPNLYNDGKVCLSILNTWHGRPEEKWNPQTSSFLQVLVSVQSLILVAEPYFNEPGYERSRGTPSGTQSSREYDGNIRQATVKWAMLEQIRNPSPCFKEVIHKHFYLKRVEVMAQCEEWIADIQQYSSDKRVGRTMSHHAAALKRHTAQLREELLKLPCPQGLDPDIEDASPVCRATAGAEETLTHDHVKPSSSKDIPSDFQL------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88738-1", "uniprot_id": "BIRC6_MOUSE", "id": "O88738-1", "name": "Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6", "aln": "---------------------------------------------------------MVTGCGAAPPGTVTERLPSVIVLSAGRKMAAAAAEASGPSCSSAAAAAGAGAAGVSEWLVLRDG-CMRCDADGLHSLSYHPALNAILAVTSRGTIKVIDGTSGATLQASALSAKPGGQVKCQYISAVDKVIFVDDYAVGCRKDLNGILLLDTALQTPVSKQDDVVQLELPVTEAQQLLSACIEKIDVSSTEGYDLFITQLKDGLKNTSHETAANHKVAKWATVTFHLPHHVLKSIASAIVNELKKINQNVAALPVASSVMDRLSYLLPSARPELGVGPGRSVDRALMYSEANRRETFTSWPHVGYRWAQPDPMAQAGFYHQPASSGDDRAMCFTCSVCLVCWEPTDEPWSEHERHSPNCPFVKGEHTQNVPLSVTLATSPAQLPSADGADRIACFGSGSCPQFLAAATKRGKICIWDVSKLMKVHLKFEINAYDPAIVQQLILSGDPS---SGVDSRRPTLAWLEDSSS----CSDIPKLEGDSDDLLEDSDSEEHSRSDSVTGHTSQKEAMEVSLDITALSILQQPEKLQWEIVANVLEDTVKDLEELGANP---SLTNSKSEKTKEKHQEQHNIPFPCLLAGGLLTYKSPATSPISSN-SHRSLDGLSRTQGES--ISEQGSTDNESCTN-SELNSP------LVRRTLPVLLLYSIKESDEK-AGKIFSQMNNIMSKSLHDDGFTVPQIIEMELDNQEQLLLQDPPVTYIQQFADAAASLTSPDSEKWNSVFPKPGALVQCLRLPKFAEEETLCIDSITPCADGIHLLVGLRTCSVESLSAINQVEALNNLNKLNSALCNRRKGDLESN--LAVVNGANISVIQHESPADVPEHLLIRPEQRNVVSGGYLVLYKMNYTTRIVTLEEEPVKIQHIKDPQDTITSLILLPPDILDNREDDCEEPAEEMQLASKN------------------GIEREKKSDISTLGHLVVTTQGGYVKVLDLSNFEILAKVEPPKKEGTE-EQDTFVSVIYCSGTDRLCACTKGGELHFLQIGGTCDDIDEADILVDGSLSKGIEPALEGSRPLSNPSSPGISGVELLVDQPFTLEILTSLVELTRFETLTPRFSATVPPCWVEVQQEQQQRRHPQHLHQQHHGDAAQHTRTWKLQTDSNSWDEHVFELVLPKACMVGHVDFKFVLNSNITSVPQIQVTLLKNKAPGLGKAN--------------ALNIEVEHNGNPSLVDLNEEMHHMDVEESQCLRLCPFLEDHKEDILCGPVWLASGLDLSGHAGMLTLTSPKLVKGMAGGKYRSFLIHVKAVSDRGA----------------------------------------------ADEMCSSGLRPVVRLPSLKQQGHKGYSLASLLAKVAAGKEKSSNVKNENAGGTRKSENLR-GCDLLQEVSVTIRRFKKTS-ICKERVQRCAMLQFSEFHEKLLNTLCRRSDDGQVTEHAQSLVLDALCWLAGVHSNGSGSSKE--------------------GNECLLSKTRKCLSDIVRVCFFEAGRSIAHKCARFLALCISNGKCEPCQPG----FGSVLLKALLDNMCFLPAAATGGSVYWYFVLLNYVKDED-LAGCSTACAALLTAVSRQLQDRLTPLEALLQTRYGLYSSPFDPVLFDLEMSGSSWKTVYSSSTAVQSDEIDLSDVLSGNGRVSS------------CTAAEGSFTSLTGLLEVEPLHFTCVSTSDGTRIERDDASTFTVSSFGVPPAVGGLSSGTVG--EASTALSSAAQVALQSLSHAMASAEQQLQVLQEKQQQLLKLQQQKAKLEAKLHQTTAAAAAAASAAAAAAAGPVHNAVPSNPVAAPGFFIHPSDVIPPTPKTTPLFMTPPLTPPN-EAVSVVINAELAQLFPGSVIDPPAVNLAAQNKNSSKSRMNPLGSGLALAISHASHFLQPPPHQSIIIERMHSGARRFVTLDFGRPILLTDVLIPTCGDLASLSIDIWTLGEEVDGRRLVVATDISTHSLILHDLIPPPVCRFMKITVIGRYGSTNARAKIPLGFYYGHSYILPWESELKLMHDPLRGEGESASQPEIDQHLAMMVALQEDIQCRYNLACHRLEALLQSIDLPPLNSANNAQYFLRKPDK----AVEEDSRVFSAYQDCIQLQLQLNLAHNAVQRLKVAIGASRKLLNETSG-----PEDLIQTSSTEQLRTIVRYLLDTLLSLLHSSNGHSVPAVLQSTFHAQACEELFKHLCISGTPKIRLHTGLLLVQLCGGERWWGQFLSNVLQELYNSEQLLIFPQDRVFMLLSCIGQRSLSN----SGVLESLLNLLDNLLSPLQPELSMH------RRTEGVLDIPMISWVVMLVSRLLDYVATVEDEAAAAKKPLNGKDRERFLTGNQWSFINNNLHTQNLNRSSKGG-SSLDRLYSRKIRKQLVHHKQQLNLLKAKQKALVEQMEKEKIQSNKGSSYKLLVEQAKLKQATSKHFKDLIRLRRTAEWSRSNLDTEVTTTKESPEIEPLPFTLAHDRCISVVQKLVLFLLSMDFTCHADLLLFVCKVLARIANATRPTIHLCEIVNEPQLERLLLLLVGTDFNRGDISWGGAWAQYSLTCMLQDILAGELLAPVAAEAMEECTVSEDVGATAG---DSDDSLQQ-SPAQLLETIDEPLTHEIAG-----------TPPLSSLEKDKEIDLELLQDLMEVDIDPLDIDLEKDPLAAKVFKPISSTWYDYWGADYGTYNYNPYIGGLGMPVAKPPSNT--EKNGSQTVSVSVSQALDARLEVGLEQQAELMLKMMSTLEADSILQALTNTSPTFSQSPTGTDDSLLG-NLQPANQNSQLMIQLSSVPMLNVCFNKLFSMLQVHH--VQLESLLQLWLTLSLNSSSSGNKENGADIFLYNANRIPVISLNQASIASFLTVLAWYPNTLLRTWCLVLHSLTLMTNMQLNSGSSSSIGIQETTAHLLVSDPNLIHVLVKFLSGTSPHGTNQHSPQVGPTATQAMQEFLTRLQVHLSST---CPQIFSELLLKLIHILSTERGAFQTGQGPLDAQVKLLEFTLEQNFEVVSVSTISAVIESVTFLVHHYITCSDKVMSRSGSDSSAGARACFGGLFANLIRPGDAKAVCGEMTRDQLMFDLLKLVNILVQLPLSSNREYSARVSVTTNTTDSVSDEEKVSGGKDVNGS-SASTPGSPACVADLVLANQQIMSQILSALGLCNSSAMAMIIGASGLHLTKHENFHGGLDAISVGDGLFTILTTLSKKASTVHMMLQPILTYMACGYMGRQGSLATCQLSEPLLWFILRVLDTSDALKAFHDMGGVQLICNNMVTSTRAIVNTARSMVSTIMKFLDSGPNKAVDSTLKTRILASEPDN------------------AEGIHNFAPLGTITSSSPTAQPAEVLLQATP-PHRRARSAAWSYIFLPEEAWCDLTIHLPSAVLLKEIHIQPHLASLATCPSSVSVEVSADG-VNMLPLSTPVVTSGLTYIKIQLVKAEVASAVCLRLHRPRDASTLGLSQIKLLGLTAFG------------------------TTSSATVNNPFLPSEDQVSKTSIGWLRLLHHCLTHISD-----LEGMMASAAAPTANLLQTCAALL--MSPYCGMHSPNIEVVLVKIGLQSTRIGLKLIDILLRNCAASGSDPTDLNSPLLFGRLNGLSSDSTIDILYQLGTTQDPGTKDRIQALLKWVSDSAKMAALKRSGRMNYMCPSSS-AVEYGLLMPSPSHLHCVAAILWHSYELLVEYDLPALLDRELFELLFNWSMSLPCNVVLKKAVDSLLCSMCHIHPNYFSLLMGWMGIIPPP---VQCHHRLSMTDDSKKQ---DLSSSLTDDSKNAQA----PLSLTESHLATLASSSQSPEAIKQLLDSGLPSLLVRSLASFCFSHISYSESIAQSVDNSQDKLR--------------------RHHVPQHCNKMPITADLVAPILRFLTEVGNSHIMKDWLGGSEVNPLWTALLFLLCHSGSTAGGHNLGAQQSS--------TRSASHSSAT---------------TTVLTTQQRTAIENATVAFFLQCISCHPNNQKLMAQVLCELFQTAPQRGSLPTSGNISGFVRRLFLQLMLEDEKVTMFLQSPCPLYKG-RINATSHVIQHPMFGAGHKFRTLHLPVSTTLSDVLDRVSDTPSITAKLISEQKDDKEKKNHEEKEKVKAENGFQDNYSVVVASGLKSQSKRAMASTPPRPPSRRGRTIPDKIGSASSSADAASKIITVPVFHLFHRLLAGQPLPAEMTLAQLLTLLYDRKLPQGYRSIDLTVKLGSKVITDPSLSKTDSFKRLHPEKDHGDLVGSCPEDEALTPSDECMDGVLDESLLETCPIQSPLQVFAGMGGLALIAERLPMLYPEVIQQVSAPVIASTTQEKPKDSDQFEWVTIEQSGELVYEAPETIAAEPPPVKSAVQATSPIPAHSLAAFGLFLRLPGYAEVLLKERKHAQCLLRLVLGVTDDGEGSHILQSPSANVLPTLPFHVLRSLFSATPLTTDDGVLLRRMALEIGALHLILVCLSALSHHAPR---------------------------VPNSSLSQTEPQVSNSHNPTSAEEQQLYWAKGTGFGTGSTASGWDVEQALTKQRLEEEHVTCLLQVLASYINP---MSGAVNGEAQASPESRAQNSSALPSVLLELLSQSCLIPAMSSYLRNDSVLDMARHVPLYRALLELLRAIASCTSMVPLLLPLSTENGEEEED-EQSECQTSVGTLLAKMKTCVDTYTNRLRSKREN----VKAGVKPDAPDQEPEGLALLVPDIQRTAEIVHAATANLRQANQEKKLGEYSKKVVMKPKPLSVLKSLEEKYVAVMKKLQFDTFEMVSEDDDGKLGFKVNYHYMSQVKNANDANSAARARRLAQEAVTLSTSLPLSSSSSVFVRCDEERLDIMKVLITGPADTPYANGCFEFDVYFPQDYPSSPPLVNLETTGGHSVRFNPNLYNDGKVCLSILNTWHGRPEEKWNPQTSSFLQVLVSVQSLILVAEPYFNEPGYERSRGTPSGTQSSREYDGNIRQATVKWAMLEQIRNPSPCFKEVIHKHFYLKRIELMAQCEEWIADIQQYSSDKRVGRTMSHHAAALKRHTAQLREELLKLPCPEGLDPDIEDASPVCRATAGAEDTLTHDHVNPSSSKDLPSDFQL------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NR09-1", "uniprot_id": "BIRC6_HUMAN", "id": "Q9NR09-1", "name": "Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6", "aln": "---------------------------------------------------------MVTGGGAAPPGTVTEPLPSVIVLSAGRKMAAAAAAASGPGCS---SAAGAGAAGVSEWLVLRDG-CMHCDADGLHSLSYHPALNAILAVTSRGTIKVIDGTSGATLQASALSAKPGGQVKCQYISAVDKVIFVDDYAVGCRKDLNGILLLDTALQTPVSKQDDVVQLELPVTEAQQLLSACLEKVDISSTEGYDLFITQLKDGLKNTSHETAANHKVAKWATVTFHLPHHVLKSIASAIVNELKKINQNVAALPVASSVMDRLSYLLPSARPELGVGPGRSVDRSLMYSEANRRETFTSWPHVGYRWAQPDPMAQAGFYHQPASSGDDRAMCFTCSVCLVCWEPTDEPWSEHERHSPNCPFVKGEHTQNVPLSVTLATSPAQFPCTDGTDRISCFGSGSCPHFLAAATKRGKICIWDVSKLMKVHLKFEINAYDPAIVQQLILSGDPS---SGVDSRRPTLAWLEDSSS----CSDIPKLEGDSDDLLEDSDSEEHSRSDSVTGHTSQKEAMEVSLDITALSILQQPEKLQWEIVANVLEDTVKDLEELGANP---CLTNSKSEKTKEKHQEQHNIPFPCLLAGGLLTYKSPATSPISSN-SHRSLDGLSRTQGES--ISEQGSTDNESCTN-SELNSP------LVRRTLPVLLLYSIKESDEK-AGKIFSQMNNIMSKSLHDDGFTVPQIIEMELDSQEQLLLQDPPVTYIQQFADAAANLTSPDSEKWNSVFPKPGTLVQCLRLPKFAEEENLCIDSITPCADGIHLLVGLRTCPVESLSAINQVEALNNLNKLNSALCNRRKGELESN--LAVVNGANISVIQHESPADVQTPLIIQPEQRN-VSGGYLVLYKMNYATRIVTLEEEPIKIQHIKDPQDTITSLILLPPDILDNREDDCEEPIEDMQLTSKN------------------GFEREKTSDISTLGHLVITTQGGYVKILDLSNFEILAKVEPPKKEGTE-EQDTFVSVIYCSGTDRLCACTKGGELHFLQIGGTCDDIDEADILVDGSLSKGIEPSSEGSKPLSNPSSPGISGVDLLVDQPFTLEILTSLVELTRFETLTPRFSATVPPCWVEVQQEQQQRRHPQHLHQQHHGDAAQHTRTWKLQTDSNSWDEHVFELVLPKACMVGHVDFKFVLNSNITNIPQIQVTLLKNKAPGLGKVN--------------ALNIEVEQNGKPSLVDLNEEMQHMDVEESQCLRLCPFLEDHKEDILCGPVWLASGLDLSGHAGMLTLTSPKLVKGMAGGKYRSFLIHVKAVNERG-----------------------------------------------TEEICNGGMRPVVRLPSLKHQSNKGYSLASLLAKVAAGKEKSSNVKNENTSGTRKSENLR-GCDLLQEVSVTIRRFKKTS-ISKERVQRCAMLQFSEFHEKLLNTLCRKTDDGQITEHAQSLVLDTLCWLAGVHSNGPGSSKE--------------------GNENLLSKTRKFLSDIVRVCFFEAGRSIAHKCARFLALCISNGKCDPCQPA----FGPVLLKALLDNMSFLPAATTGGSVYWYFVLLNYVKDED-LAGCSTACASLLTAVSRQLQDRLTPMEALLQTRYGLYSSPFDPVLFDLEMSGSSCKNVYNSSIGVQSDEIDLSDVLSGNGKVSS------------CTAAEGSFTSLTGLLEVEPLHFTCVSTSDGTRIERDDA----MSSFGVTPAVGGLSSGTVG--EASTALSSAAQVALQSLSHAMASAEQQLQVLQEKQQQLLKLQQQKAKLEAKLHQTTAAAAAAAS-----AVGPVHNSVPSNPVAAPGFFIHPSDVIPPTPKTTPLFMTPPLTPPN-EAVSVVINAELAQLFPGSVIDPPAVNLAAHNKNSNKSRMNPLGSGLALAISHASHFLQPPPHQSIIIERMHSGARRFVTLDFGRPILLTDVLIPTCGDLASLSIDIWTLGEEVDGRRLVVATDISTHSLILHDLIPPPVCRFMKITVIGRYGSTNARAKIPLGFYYGHTYILPWESELKLMHDPLKGEGESANQPEIDQHLAMMVALQEDIQCRYNLACHRLETLLQSIDLPPLNSANNAQYFLRKPDK----AVEEDSRVFSAYQDCIQLQLQLNLAHNAVQRLKVALGASRKMLSETSN-----PEDLIQTSSTEQLRTIIRYLLDTLLSLLHASNGHSVPAVLQSTFHAQACEELFKHLCISGTPKIRLHTGLLLVQLCGGERWWGQFLSNVLQELYNSEQLLIFPQDRVFMLLSCIGQRSLSN----SGVLESLLNLLDNLLSPLQPQLPMH------RRTEGVLDIPMISWVVMLVSRLLDYVATVEDEAAAAKKPLN---------GNQWSFINNNLHTQSLNRSSKGS-SSLDRLYSRKIRKQLVHHKQQLNLLKAKQKALVEQMEKEKIQSNKGSSYKLLVEQAKLKQATSKHFKDLIRLRRTAEWSRSNLDTEVTTAKESPEIEPLPFTLAHERCISVVQKLVLFLLSMDFTCHADLLLFVCKVLARIANATRPTIHLCEIVNEPQLERLLLLLVGTDFNRGDISWGGAWAQYSLTCMLQDILAGELLAPVAAEAMEEGTVGDDVGATAG---DSDDSLQQ-SSVQLLETIDEPLTHDITG-----------APPLSSLEKDKEIDLELLQDLMEVDIDPLDIDLEKDPLAAKVFKPISSTWYDYWGADYGTYNYNPYIGGLGIPVAKPPANT--EKNGSQTVSVSVSQALDARLEVGLEQQAELMLKMMSTLEADSILQALTNTSPTLSQSPTGTDDSLLG-GLQAANQTSQLIIQLSSVPMLNVCFNKLFSMLQVHH--VQLESLLQLWLTLSLNSSSTGNKENGADIFLYNANRIPVISLNQASITSFLTVLAWYPNTLLRTWCLVLHSLTLMTNMQLNSGSSSAIGTQESTAHLLVSDPNLIHVLVKFLSGTSPHGTNQHSPQVGPTATQAMQEFLTRLQVHLSST---CPQIFSEFLLKLIHILSTERGAFQTGQGPLDAQVKLLEFTLEQNFEVVSVSTISAVIESVTFLVHHYITCSDKVMSRSGSDSSVGARACFGGLFANLIRPGDAKAVCGEMTRDQLMFDLLKLVNILVQLPLSGNREYSARVSVTTNTTDSVSDEEKVSGGKDGNGS-STSVQGSPAYVADLVLANQQIMSQILSALGLCNSSAMAMIIGASGLHLTKHENFHGGLDAISVGDGLFTILTTLSKKASTVHMMLQPILTYMACGYMGRQGSLATCQLSEPLLWFILRVLDTSDALKAFHDMGGVQLICNNMVTSTRAIVNTARSMVSTIMKFLDSGPNKAVDSTLKTRILASEPDN------------------AEGIHNFAPLGTITSSSPTAQPAEVLLQATP-PHRRARSAAWSYIFLPEEAWCDLTIHLPAAVLLKEIHIQPHLASLATCPSSVSVEVSADG-VNMLPLSTPVVTSGLTYIKIQLVKAEVASAVCLRLHRPRDASTLGLSQIKLLGLTAFG------------------------TTSSATVNNPFLPSEDQVSKTSIGWLRLLHHCLTHISD-----LEGMMASAAAPTANLLQTCAALL--MSPYCGMHSPNIEVVLVKIGLQSTRIGLKLIDILLRNCAASGSDPTDLNSPLLFGRLNGLSSDSTIDILYQLGTTQDPGTKDRIQALLKWVSDSARVAAMKRSGRMNYMCPNSS-TVEYGLLMPSPSHLHCVAAILWHSYELLVEYDLPALLDQELFELLFNWSMSLPCNMVLKKAVDSLLCSMCHVHPNYFSLLMGWMGITPPP---VQCHHRLSMTDDSKKQ---DLSSSLTDDSKNAQA----PLALTESHLATLASSSQSPEAIKQLLDSGLPSLLVRSLASFCFSHISSSESIAQSIDISQDKLR--------------------RHHVPQQCNKMPITADLVAPILRFLTEVGNSHIMKDWLGGSEVNPLWTALLFLLCHSGSTSGSHNLGAQQTS--------ARSASLSSAA---------------TTGLTTQQRTAIENATVAFFLQCISCHPNNQKLMAQVLCELFQTSPQRGNLPTSGNISGFIRRLFLQLMLEDEKVTMFLQSPCPLYKG-RINATSHVIQHPMYGAGHKFRTLHLPVSTTLSDVLDRVSDTPSITAKLISEQKDDKEKKNHEEKEKVKAENGFQDNYSVVVASGLKSQSKRAVSATPPRPPSRRGRTIPDKIGSTSG-AEAANKIITVPVFHLFHKLLAGQPLPAEMTLAQLLTLLYDRKLPQGYRSIDLTVKLGSRVITDPSLSKTDSYKRLHPEKDHGDLLASCPEDEALTPGDECMDGILDESLLETCPIQSPLQVFAGMGGLALIAERLPMLYPEVIQQVSAPVVTSTTQEKPKDSDQFEWVTIEQSGELVYEAPETVAAEPPPIKSAVQTMSPIPAHSLAAFGLFLRLPGYAEVLLKERKHAQCLLRLVLGVTDDGEGSHILQSPSANVLPTLPFHVLRSLFSTTPLTTDDGVLLRRMALEIGALHLILVCLSALSHHSPR---------------------------VPNSSVNQTEPQVSSSHNPTSTEEQQLYWAKGTGFGTGSTASGWDVEQALTKQRLEEEHVTCLLQVLASYINP---VSSAVNGEAQSSHETRGQNSNALPSVLLELLSQSCLIPAMSSYLRNDSVLDMARHVPLYRALLELLRAIASCAAMVPLLLPLSTENGEEEE--EQSECQTSVGTLLAKMKTCVDTYTNRLRSKREN----VKTGVKPDASDQEPEGLTLLVPDIQKTAEIVYAATTSLRQANQEKKLGEYSKKAAMKPKPLSVLKSLEEKYVAVMKKLQFDTFEMVSEDEDGKLGFKVNYHYMSQVKNANDANSAARARRLAQEAVTLSTSLPLSSSSSVFVRCDEERLDIMKVLITGPADTPYANGCFEFDVYFPQDYPSSPPLVNLETTGGHSVRFNPNLYNDGKVCLSILNTWHGRPEEKWNPQTSSFLQVLVSVQSLILVAEPYFNEPGYERSRGTPSGTQSSREYDGNIRQATVKWAMLEQIRNPSPCFKEVIHKHFYLKRVEIMAQCEEWIADIQQYSSDKRVGRTMSHHAAALKRHTAQLREELLKLPCPEGLDPDTDDAPEVCRATTGAEETLMHDQVKPSSSKELPSDFQL------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B748-1", "uniprot_id": "A0ACD6B748_DANRE", "id": "A0ACD6B748-1", "name": "Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6", "aln": "-------------------------------------------------------------------------------------MAAAAGASPG----------------SPDWVVLRDG-CLRCDEEGLRSLSYHPALNAILAVTSRGSIKVIDGTSGAILQASALHAKPGGRVRCQYFPAVDKVLFVDDYAVGCRKDLNGILLLDTALQAPVSKPEDMVQLELPVTEAQQMLYACMEKVDVSNTEGYDLFLTQLKEGLENTSHETAANHKVAKWATVTFHLPHHVLKVVTNAIVNELKKLNQNVAALSVASSVMDRLSYLLPSGRPELGVGPGRSVDRSLMYSEANRRETFTSWPHSGYRWAQPDPMAQAGFYHQPASTGDDRAMCFTCSVCLVCWEPTDEPWSEHERHSPNCPFVKGEHTQNVPLSVTLATSPAQFPSADGSDKIVCYGFGSCPHFLATATKRGKICIWDVSKLMKVHLKFEVNPYDPAILRQLILSGSEQQNLTGTELRRPTLSWLEEATC----CSDLPKLEGDSDDQIEDSDSEEHSRSESVTGPLGQKETMEVSLGVTALSVLQQPEKLQWEVVASVLEDTVKDLEELGANPPH-SLGPPKADKAKDRPAEHHNIPFPCLLAGGLLSYRSAASSPLGPPPSRRSMDSPVRTAAPEGLAPDQGPMEIESCNPSTDLGSPNLPPAAPVHRTMPVLLLYSIKEADEKSSGKVFTQMNNLMSKGLHDEGFTVPQIIEMEFDSHEQLLLQDPPITYIQQFADAAAGLGPLDGEKWSSVAPRPGSLVQCLRLPKALEEENLYVDSITPCSDGLHLLVGLQPCSVESLSAINQVEVLNTLNRLHSALCGHRKGQTLANGHDAHTGTSPPQTPLILPPPDQQQPHTSRPLGGS-GGGGYLALYKLNYSTRIVTLEEEPVKVQQIRDPRDAVTSLLLLPPDVLDGREDDGEETSEESTPSGLKNGTGTVASTITAGPSLGSATGKEKRGEVAGLGHLVVTTQAGYIMILDLSTLEVLAKVEPAKKEGTE-EVDPFVSVTYCSGTDRLCACTKGGELHFLQIGGVCDDIDDADIFVDGPLSNRADQLLDGAKPTSNPSSPGITGVDLLVDQPLTVETLSSLVELTRFETLTPRFSATVPPCWVEVQQEQQQRRHPQHLHQQHHGDAAQHTRTWKLQSDSSSWDEHVFELVLPKACMVGHVDFKFVLNSSITNIPQIQVTLLKNKAPGLGKVNETAVDRQIVFPLSHVLHSNGEKNGQPHLLDFSEDIQFMDIEESPGYRLCPFLQEHKDDILCGPVWLSSGLDLSGHAGMLSLTSPKLLKGMAGGKYRSFLVHIKAVSDKG---------------------------------------------------LDEGLRPVVRMPSAKPQSSKAHSLSSLLQRAQATKEKASTSKADPQSVPKKPDNLR-GCDLLQEVSVTIRRFKKTS-VPKERVQRCAMLQFPELHEKLLRGLCKRGEDSQSSEHCQSLILDILCWLAGVYSNGPCSLRE--------------------GKEGLLTKTRRRLTDIIRACFFEAGRSIAHKCSRFLALCISTGKGDPGQQG----FGQALFKALLDNMPYLPAAATGGSVFWYFVLLNYVKDED-LAGCSTACASLLTAVSRQLQDRLTPLEALLQTRYGLYGSPFDPVLFDLEVSGSSCKNAFSSGIGVQSDEIDLSDILSGNGKVNS------------SGAAEGSFTALTGLLEVEPLHFTCVSTSDGTRVERDDASMFTVSTFGVTPTVTGLSAGSVG--EASTALSSAAQVALQSLSHAMVSAEQQLQVLQEKQQQLLKLQQQKAKLEAKLHQTTSAAATAAS--------GVVNSVPSNPSSAPGFFIHPSDVIPPTPKTTPLFMTPPLTPPN-EAVSAAISVELAQLFPGSVIDPPPVNLSAQNKNNQKAKPNPMGSGLALAISQASHFLQPPPHQSIIIERMHSGARRFVTLDFGRPVLLTDALIPTCADLASLSIDIWTLGEEVDGRRLVVATDISTHSLILHDLLPPPVCRFMKITVIGRYGSTNARAKIPLGFYYGHTYILPWESELKLMHDPLRGESEAAGQPDLDQHLSMMVALQEDIQCRYNLACHRLETLLQNIDLPPLNSANNAQYFLRKPDK----AVEEDSRVFSAYQDCIQLQLQLNLAHHAVQRLRVSLGATRKHLPENYD-----PRELVQNSSTEQLRTIIRYLLDTLLSLLHSCNGNSVPSVLQNTFHAQACEELFKQLCISGTPKIRLHAGLLLVQLCGGERWWGQFLSNVLQELYNSEQLLIFPQDRVFMLLSCIGQRSLSN----SGVLEGLLNLLDTLLSPLQQASAAQP-----RRTEGVLDIPMISWVVMLVSRLLDYVASVEDEASAAKKPLGAKDRERSFTGNQWSFINNSLQSQNPSRSAKGSNSSLDRLYSRKIRKQLVHHKQQLNLLKAKQKALVEQIEKEKIQSNKGSSYKLLVEQAKLKQATSKHFKDLIRLRRTAEWPRSTLDSEASVAKETPEVELLPFTLAHERCICVVQKLALFLLSMDFTCHADLLLFVCKVLARIANATRPTIHLCEVVSEQQLERLLLLLVGTDFNRGDISWGGAWAQYSLTCMLQDILAGELLSPGCVDGMEGAGADEAGAASSSVVVDSDDSLPQPTPIPLVETIDEPLGPDIIAGTPGTSSVFQSAPPLSSLEKDKEIDFDLLQDLMDVDIDPLDIDLEKDPLAAKVFKPISSTWYDYWGADYGSYSYNPYTGGVGIPVSKPPAATTVEKPGSQNLSVSVSQALDARLEVGLEQQAELMLKMMATLEADAILQALTSTSPSVAQSANGTDDSLLRGGFHNSPPSSSLMVQASSIPMLSTCFNKLFSLLQVHH--VQLESLLQLWLTLSLSSCSGGSEESGSDIFLFNASRVPTIPLNQASISSFLSVLAWYPNTSLRTWCLVLHSLTLMTNMPA-CASSSGMGVQESTAQQMVSDPTLVHVLVRFLSGGNPHGTSQHSSQVGPTATQALQEFLTRLQVHLSST---CPQMFSEFLLKLLHILSTERGPFQSGQGPLDAQVKLLEFTLEQNFEVVSVTTILAVIESITFLVHHYITCSDKVVSRSGSDSSVGARACFGGLFANIIRPGDAKAVCGETTRDQLMFDLLKLVNALVMLPLSGDREFSGRLPPAGGATDSVSDEEKVCGSKECGAAGTAQHQGPAAGVADLVLANQQIMSQILSALGQCNSSAMAMIIGASGLHLTKHENFHGGLDAISVGDGLFTILTTLSKRATSVQVMLQPILTYMACGYMGRQGSLSTCQLSEPLLWFILRVLDTSEALKAFHDMGGVQLICNNMVTSTRAIVNTARSMVSTIMKFLDSGPGKAADGSLKARVLTSEPDN------------------AEGLHNFAPLGTITSSSPTAQPAEVLLQATP-PHRRARSAAWSYIFLPEEAWCDLTIHLPAAVLLKEIHIQPHLASLATCPSSVSVEISADG-VNMLPLSTPVITSGLTYIKFQLVKAEVASAVCLRLHRPRDASTLGLSQIKLLGLTAFG------------------------NTSSATVNNPFLPSEDQVSKTSIGWLRLLHHCLTHVSD-----LEAMMASAAAPTANLLQTCAALL--MSPYCGMHSPNIEAVLVKIGLQSTRIGLKLIDILLRNCAASGTDLANLNSPLLFGRLNGLSSDSTIDILYQLGTTQDPGTKDRIQALLQWVYDSSRVASLKQSSPSGYVGPIAPPPREYGLLMPSPSHLHCVASVLWHSYELPVDYDLPGLLNRELFELLYNWSMSLPSNMVLKKAVDSLLCSMCHIHPNYFSLLMSWMGIVAPSSAQTNAQRRMAMTDDGKKQHDLNSAASLTDDSKHARTPVTVPISLSECQLVTLAAASQSPGAIQQLLDSGLPSLLVRSLADLCCNLLVSADLPLPSGFSSQTERRPY----------------SHNQHSPSSTNRPPLSPELAAPVLRFLTEVGNSHTMKDWLGGPEVNPLWTALLFLLCHS-SASGTANANANSSSSSVCGHGASPSTSHASAAPHTSGASYSLASSSRSSGLTTQQRTAIENATVAFFLQCISCHPNNQRLMAQVLCELFQSAPQRGNVPVSGNISGFIRRLFLQLMLEDEKVTVFLQSPCPLYKG-RINATSHVIQHPMYGAGHKFRKLHLPISTTLSEVLDRVSDTPSITAKLINEQKEDKEKKNHEEKEKMKADNGFQDNYSVVVASGLKSQSKRALS-TPPRPPSRRGRVLSDKLAASSG-VDPSAKTISVPVFHLCHKLLPGQPLPPEMTLAQLLTLLYERKLPQGYRSIDLTVKLGSKIISDPGLSKTDSFKRLRTEKDHCEMLSGCPDDEPMTPGDEGLDAAVDDSLLETSPIQSPLQVFAGMGGLALIAERLPMLYPDVIQQVSAPVVPSTTQEKPKDSDQFEWVTIEQSGELVYEAPETIAAEPPPIKSSVQTMSPIPAHSLAAFGLFLRLPGYAEVLLKERKHAQCLLRLVLGVTDDGEGSHILQSPSANVLPTLPFHVLRSLFSSTPLTTDDGLLLRRMALEIGAIHLILACLSALSHHAPR---------------------------VPSGSANSSEPQVSSGHVGGTTEEQQLYWAKGTGFGTGSTASGWDVEQALTKQRLEEEHVTCLLQVLASYINP---SGCVGSGETLTG-EVRGHSSSLLPSVLQELLSQSCLIPAMSSYLRNDSVLDMARHVPLYRALLELLRAISTCTSLVPLLLPLSGDAAEEEEDEERIECQTSVGMLLAKMKTCVDTYTNRLRSKKDK----SKGVMKAETSDPEPEGLTLLVPDIQKTAEIVYAATTNLRQANHERKMAESSKKAAARPKPLSILRSMEEKYTAAMKKLQFDTFEMVCEDEDSKLVFKVNYHYLSQVKNASDANSAARARRLAQEAVTLSTSLPLSSSSSVFVRCDEERLDIMKVLITGPADTPYANGCFEFDVYFPQDYPNSPPLVNLETTGGHSVRFNPNLYNDGKVCLSILNTWHGRPEEKWNPQTSSFLQVLVSIQSLILVAEPYFNEPGYERSRGTPSGTQSSREYDGNIRQATVKWAMLEQMRNPSPCFKEVIHRHFYLKRAEIMAQCESWICDIQQYSSDKRVGRTMSHHAAALKRHTAQLREELLKLPCPEGLEPDGEEFSEKSTSLMVKELPSQDTEKQTDSPDAHCSDGQL------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KG50-1", "uniprot_id": "A0A0B4KG50_DROME", "id": "A0A0B4KG50-1", "name": "Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6", "aln": "-------------------------------------------------------------------------------------MATEQHHQQRVLKQ-------------DGYLDLGDCNSAPSRPFEMRNVVYHPQLNVLLLFDNGSTVKVLDANSGVILQTYHLSSNGDSIVHGRYMPLQDKILFWDGHNLGLRGDYNGVLLLDTILQAPIGQNDDYIKLEIILSEAIIFQN-CITELESEGLECPCDISNELTQKINQAQLKAKKGIKAQRWNTICLEVPYSSLKLVSNNMVILLKRLERHIPVLAIASAINERLTDMMMGSRVPDFGWNFSNFQRVLMHSEAVRRQTFEKWPHMDYKWALPDQMAQAGFYHQPSSSGEDRAMCFTCSVCLVCWEKTDEPWSEHERHSPLCPFVKGEYTQNVPLSITYATNPALPAPGLGFDIISNS--DYANVLCTSCSQTGELSVWSIERHLKLMHTFHVPTLLNYIFEESFEWARVTAICVLPNARARTKVNYVYSAANYGGSGSSNGAGCNSGLNAVSGGKFGSVNAQHITSTSTLRAGVVGSKIVLGVSVRQSSGELALRMVVLNIVEVDRNSESSTSVSNDSGSVSSGGGQLMKSSSPMVNVSAENNATVTQVNLESKDDDNKAMTPYEKFADGFDSNGFVSALMTYNKNNGVSQNTDDASALYDFDLCTLSQILDHNLEEPLSLMVGSSNTVNVSNIGMGNEINKLVVDVEISHQNNNNNNNNNNEASSLGGNSSNNNNNIMINGGTNSSIDKMTAIEEIDCVVESWTSVKRMNALDGASSGVNGVNHMDQEVIEIAEILPTTPKCNQLLVKLLRTKAPEAEGSKIIMATVAKEEEE-----EDEEQRTDESMETDNNAEGNVAAQLLVFDYDDTEISNDYTLAMTFSRAKFPKQLCILPHFNSSPEHKDAGSICVVCADGTVEIYSLADFQGTMVIEEE------------------GEHFESVVYCRNLDRLCCCSRQGGLLFYSLSDGENDSGDELLEMDDDCSTTLTQAADVSVTDGGRQLARTDLLGKTLLANESICMDAGSEAAAIPNSSSAAQGAHVQTSPSASSAPSTNAN-LLAYKTADLTLEDLKVFYALTQFDDKLTVYSAEVPSCWNDIGQVQNQRKQSQNMR--HGGDERDFTRTWRLHNDATTWDEHIIELNLAQPVSLGHIDLKFTVYQQCSNPAAIQVTLLKQNNNGFGYRMKG-----------------PHSSYKPNVIDDNIDLSYIANENP--VLSEEYLLAHNAEVLAGPIELSSCIDLCDQGGTATLTSPKLFK----TRTRNFLLHIKTVSDPSKDGQNKTRDSPTRHKRPHHVEGFVERNKVSRNPFNVAANIISVVKTAVLEVFPAAKNACVKIIQVNKPKTQDNEKVFVAKIIKNKTQSQSAAVAPSVGRRLEQLPSREGCDWLHEISISVRAVKSHSRISNGRMQRIAMLES----NVLLVQLLRIASDPASSSLAKNLSLDILNWICFIRLNRFRSPKSERLKDQINKQTAANIQDLLAQQFECISLAEKHIEQLLRNCVIYSERSTAHKCVKLLIMLTEGATNLPAEVQDHTTLDYSFKAAIANTFPELPRAQCGSVVRWYMMLTCATSTAESHNSISEQAISLLKEIAAEIDKRWDPHCALLCTRFGLYGYPFEPEIFDFDFPNVSRQGPGSSVANVIRSSPTILPVTGLDIKRLSSIDGVDFRTFPYLIRGKSISNQLRGLLEVVQLHFNCVQTSEATRIDNIDSVGGNTGANVIIEDVMMMPKQVVAKEKGEEMLNDLVNDVECLVEEMKVDENEKQEKVDYDAFGLVNGFKDKTLSSLNSVKQTLKEEVKKEKADIMDKLTIAKFLPKLSLLESYMQKKINEHISFDDFGKLDNWDGNTTPPFNLEVEAPIVCSEATSESNMSQQATSAGGNILDDAADSEKITESLNANPCQPIAWHKLITPPPKQMIVIDRMHSGARRFVVLDFGQHILLTDLVIPSCDELTSLNIDIWCFDEETDCTRLVQVNDIQTKTLVLSDIQPAPICRYLKLTIIGRIGMSATKCKVPLGRFFGHPVVLEHDGYGDQLMKYIKHP-----THSLQSQIKSLNALYEDVHCRYSLASSKLMDLLAPMRNSELSNVAHLQAFINKQREEELSGLENNNKVVSLYDECMLLQYQINVIRNVVLRLERALSPNSPTTTLLPGQSIPLTEDILRAASRDKLRVLSLSLVEVLLHFSIEYGIKNILPVHQR-FNAATAKALFNALVVYGDAQLQLATCSLLVRMCCFQPWWGDFLADTFCSLFSAQNCKAFPQDRIFFLLTYLGRRSIAMGACRSIVIDAVLKTLVKLLAPISPHYKFQSEQPSTSANAADRNAAMGTTSDLQLITWLLLFLSVCLDDNERKDKSAARWDFMSCEGDFTKARPSATPNIKQLRCFKKRIIQQNKYLAQPYADWGKKIYMIQNEHPGIFMELSTKSKGAGPTKSTSTGGKINMGSSGLCVGGPSSSSGNTSKSAASSSSPKNQAVPGTDGERDSNFDKGLKSLRMDNIKVVIRGLFALLLEMDFDCNMDQFLLTCKVIARLVAACRPSVQLCKIVTIAQLQQLVRLSVWNDQQ-------HPWAVHAITCLLQDLLDADKQFR-----------------------DNDVTPTNDTPRTMEAAIQETR----------------------DLFSDYTSTASSCTEALFETLMPTAREFYQEAVKYNYLPSLIECDDTEFDEMLNDIDMIERTKPVTKKESNALSKN-----TFNFFCKSISIALDSRLDVGLELHVETQLRRLTNRTSLDLYSSLPQVLTNEFVSP--PPEAAPWPEYLTQLWSGTEYNGDNTYVMFKRVFDSILAELHLEDTWVHLEQVLQMWLTLNCELSDKPYTSG------ITHSDVPKIPFGANAVQGLLLALAWHSDIKLRTWCLGFQCLFLACNSLPIGDDADCT----RINEAIVNDENFEKVLLRFFSGYGMSSSIITNRCAGPTICKHLHELLLWLHSKSETSGIPCKRRLKDILLHVVLQLVQPGGSISNQQGPIDAQNQLVRDLLMMPNDKGDLNIALKITESVSFLVYNNISNGERLQCQRGNENSP-VGNNFSNLFANVLGSENPNKQNAAICDNSLIINLLKLSSHMVLTEMPRQPSEVTIPEEEELSNQSQTDETKAEQLN------TEGHRSKVPCIADWVLRHFPTMKRLFGTLSQCSTNTFTMMSSGCFFSPKSNMILD---DPQTIADAVFSLMITLNDKASHPRLVVVPICRYLEETTIPRNATLPRLPHSEPFLWYISKVLEVPAAVQTFTQLGGIQIICHSLVRLNKTIINMQPGLISLIMQHLTRNTRFKRNNHVAASSACKKTTTGTGTTCPTSAQPPRSAAQYDGLINFAPFSHIVSENDATQSAEVLISNPNNSHRRPRSPAWTYMFYPNETHVDLTITLPTAILLKEVQLVPHTTSLASCPSAVALELSRDYGLGSIPVGAPMATTGLTCIRLKLAKAEVATSIVLRLYKPKDCGNVGLVQIAVLGQTIFGNRMHGLRSPSPFIDSLATCSSPVQTAVLAAMDADSMLEDDAFAKTSIGWVRILSRCFHVAALQPDSKLADLIAAYPAAYPGFLEACCSLLNIMPMIPSLAQQHLETILLKLSAYNHEISLQLLRTLLWHTTP---------------QVFKLSSDSVCDLIYEVVTGSTEHLLDKLRVLIDWVMQLHDNYSKQARCNN-----------------PQSGFVKVIASILWKVHTQQQLPELPLLISSSLFETCFEWVSSLEHDEPLKSSFDSLLCALCFIKPELFNQLLVKLGVKLEP-------PARGQTDDSKVQ---SGSAWFRREGSENLS----VLLQRPTFLKTLALACQSPAAVYQMLDSGLPKLLAHAIYEYCMHLMPGSEPVASASTVPEDEPLANNQAAAAADDEDSSLTDFDKAEANVVYNTPLLSSSNVPKVLDFFAECCAEGPMRDWLGTMQGSVFWKPLLQLLCNTHAAQFSKTLPKEQSFIR------------------------------------------LERATINFFTRVSACHPGNQENLTSLLIGAIICKPLRFSHGVRPTISGFTRQMVLQLLLENEHITVSVRSQQPLQRRDTLSAVLGGISSGASTSLPVAAVNNHPARRSSAHHMLFTVTTSTTCQEIMQNCVSVFSNLVYQQPTDQRAGETSASSSGVSSATAKSSESKMEKSSFLNFNNVEAG--SMEFLTVGAAVAAKDKRIKDAKNQAAMNKDKETQTSSTNLASNIFNVDEFLLQSANAVNGNQLVIPEYSDIVLAGDATISQVLASLQN-AGHSLSTPCISFDLVLQQRSDDTSEAKKTKAACTEPLPSPLQRFSSSGGLSLLAHYLPTVYPEHSGRKTTLVFS----EKEKSPPLSDWVKLEPNDEIYEDLEDTLCEP----AAKLATVSSVPQHSLAAFGLFLRLPAYSDVLLRDKMRAQCLLRLVLGVTGDGDGNDIYSLSLAPSLPTLPFEVFRQLLDSVPLSTDDGVLLRRVVIEVGAMHLVLNCLGIFSHQSHNNRIGAPISEPSPSGTSSGSGTIGNGSGNGSVSGTKTNAPEEATPSATSDDKSHMYWAKGTGFGTGSTTQSWNVEQALLRQKSEEEHVTVLLLVLASYINPGDCIPSEMCGEDILAYHDVRDVTGELPPIFQTLLQQSCLIPALSSYLRNDSVLDITRHIPLYRAILKLLRALSLSKMLVSLLQPSASGSG---------DSTPPIVELLTSMKTCVDTYAKRLKVNKKSNIKGQTHQLTFNIDDGDDEGLALLIPDIHETSVLVQKTTDADALINMLHTNEDGSAQLEPQSK------SIEQRYLELMKKRQFDTFDMIVESDNNSFRFVVSHHFEKMVRLAGDRYHPSRVKRLAQEAVTLSTSLPLSFSSSVFVRCDTDRLDIMKVLITGPADTPYANGCFEFDVFFPPDYPNQPMLINLETTGRHSVRFNPNLYNDGKVCLSVLNTWHGRPEEKWNAQTSSFLQVLVSIQSLILVPEPYFNEPGFERSRGSPSGTNSSREYNSNIYQACVRWAMLEQIRSPSQCFKDVIHKHFWLKREEICAQIEGWIEELGKPQYTERASRTISFNSMVLRRHYRHLREELSKLKPPRGLEDLDAPFNPVATLPPMDVSAVAPSLAATNTVQAQPDDAIVTDITLLGENADECEADGDAEGDGEVDDGFKGFPQEEGLLTGEEEVVEILSDTENESSMWQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **: :: * * . . ::.: *** **.:* . . .::**:*..**. **: * :: .. *: :*:. **::* *.: :* * * **:***** **:*:.: :* ::**: ::** : *: ::: .. * : .:*.: ::::. :: . *. :* *: :.:*: ** ::. :* **::::::..*.:**:: :**: :: ..* ..:* **:*** **:** .*** .*:** ** **********:*:*:**************** ************* *******:*******:* **.** . * * * . . : ::.:: *::.:*.:.: :*: .*.: . *..: : . : * * ::. ... :*. .... .:: :*. : : * : .:*: *.. :* .:*. : :. :: *. : . . . : . *:. : :. .* . . .: *. . . . : .. . :. : *: ...: . *.* :.* : * :: : : : :.:* * . . . ::: .. . * . . .:: : : . ::.:. : : :. : . . :. . : :: : : * : .. : . . : : . . *.: : ..: :: : ::... : : : . * : : . *. *.:* :: * : . .** * : * : :. . .: :. .* * *. :* . * * .. : .. * : : . *...*.. . : :*:* *. : **:*: . :** **.** :: * *:**::.*::: * ** :.****:*:.*:.:****::** *.:. :**:*:**.: . :. 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:*:.***:**:. * **:::**::*. **::*: * * .* : .** :::**:***:* .: *.* : : :. : :*:*. .* .* . : : : * :: ::.: : : .: . :. . . : ::. : . : .. *:* ***:**:**** :.* *: ::. : : .:*... .. *. . :: .. .: *:. *:.::: *::.. *:**.:**:****. . .. .. . . :* *.:. :: .:* .***:.: ****** ::.* * * .:. . :*.* .: :**::*:** . .: . .*** : ::*:* *: : .:: * : :.::**::: * *.:.. ***:*** :*:. * : .:. : **::***:: *: .::: .: *.:.* . *..****:: . :.: . :.*:::**** . :* :. : . :.:* :** *. : . . . :** ** : *.:::.:*. *.:.:::*: ... : ..: :. *. ::.*.:*::: **..:*: :::: ** *: : *:.:*. ***:**:* :**:.. *:::* ::**:*:**:.:* .::*:* .::* **:.* .. :. : : .:. . :*: ****:. *.*.. ::*.****:. . .***.**.**:*:* *:*: **** **:*:****::: ** :***:***:*::*:* * :. :*:.:*: *:*** *:::*.*****::: ***::*:*...:** ** :** * ** .: *::: : .:* .:******:*:* :*: : * ::*: .*. ..:*::*.:** *. .: . ::*.:*:*:. . .*.*:*: ** : :. :: *****. *::*:: * . *:::.*:.** : : : *....:: :*::**: : :** *:. .*** ::* ** : **.:.*****::*.::*: *. *: :*: . . ***.* * . :: : :... : : * *** :.*** *: *:******.**.::: . * : :: : .: : . . * ::.. .. :* *::* . *:**** : . :*..** ***:: :: . :.: :*.**: ** : :***.**. ::.:* : * * . . .**** *::.***:**:*::*: ::* ** : :.*. *. : : * : :. : . *.: :::.: . .: ::: . :* : .. .* *:. .*:** : . * : : :. . : . :: *. ..::: : . : : .:. .. :*.: * :: . : :: *: .* . * : .: . . . * *: **** *:. ***:*:*. ** :**: : :: *.. ** *.. :**.:* ..*: : :*:. : : : *.:* *************.*::***::: :************.**:*..* . . * ******.*:*.*:.:.**:****:****:.:*:**:**:* **. :**:: . . * ..::. . : ::.::*************:..*:***** :*: ****** ** ******** ** . . . :. **.:: **.*******:***********::**:*****:*:****:: . :*.** * : . :. ..: **:.********::**: ::.. . :. : * : ***:**:***:.*: :* :* * :. : * : :.* *:*::* **. *****:*: *.::..: * *.:*: . *: *.* .:*.:**************** ********* :**************************:** ***..* *:****** ******************:*************.***********:******.********:*****:****:*****:.** ** *:******:*.** ***:***:**:*** *: ** * ** :: : . :*..**:*.:: .*:** :***** ** *.**: . . ..: . .* : ", "identical_positions": 1294, "similar_positions": 1604, "identity": "24.28%" }, { "cls_id": "homologset.agr.MGI:1276109", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P56745-1", "uniprot_id": "CLD1_RAT", "id": "P56745-1", "name": "Claudin-1", "aln": "MANAGLQLLGFILASLGWIGSIVSTALPQWKIYSYAGDNIVTAQAIYEGLWMSCVSQSTGQIQCKVFDSLLNLNSTLQATRALMVIGILLGLIAIFVSTIGMKCMRCLEDDEVQKMWMAVIGGIIFVISGLATLVATAWYGNRIVQEFYDPMTPVNARYEFGQALFTGWAAASLCLLGGALLSCSCPRKTTSYPTPRPYPKPTPSSGKDYV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88551-1", "uniprot_id": "CLD1_MOUSE", "id": "O88551-1", "name": "Claudin-1", "aln": "MANAGLQLLGFILASLGWIGSIVSTALPQWKIYSYAGDNIVTAQAIYEGLWMSCVSQSTGQIQCKVFDSLLNLNSTLQATRALMVIGILLGLIAIFVSTIGMKCMRCLEDDEVQKMWMAVIGGIIFLISGLATLVATAWYGNRIVQEFYDPLTPINARYEFGQALFTGWAAASLCLLGGVLLSCSCPRKTTSYPTPRPYPKPTPSSGKDYV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95832-1", "uniprot_id": "CLD1_HUMAN", "id": "O95832-1", "name": "Claudin-1", "aln": "MANAGLQLLGFILAFLGWIGAIVSTALPQWRIYSYAGDNIVTAQAMYEGLWMSCVSQSTGQIQCKVFDSLLNLSSTLQATRALMVVGILLGVIAIFVATVGMKCMKCLEDDEVQKMRMAVIGGAIFLLAGLAILVATAWYGNRIVQEFYDPMTPVNARYEFGQALFTGWAAASLCLLGGALLCCSCPRKTTSYPTPRPYPKPAPSSGKDYV", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "************** *****:*********:**************:***************************.***********:*****:*****:*:*****:********** ****** **:::*** ******************:**:************************.**.*******************:********", "identical_positions": 190, "similar_positions": 17, "identity": "90.05%" }, { "cls_id": "homologset.agr.MGI:1276110", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LD71-1", "uniprot_id": "A0ABK0LD71_RAT", "id": "A0ABK0LD71-1", "name": "Claudin", "aln": "MASLGVQLVGYILGLLGLLGTSIAMLLPNWRTSSYVGASIVTAVGFSKGLWMECATHSTGITQCDIYSTLLGLPADIQAAQAMMVTSSAMSSLACIISVVGMRCTVFCQESRAKDRVAVVGGVFFILGGILGFIPVAWNLHGILRDFYSPLVPDSMKFEIGEALYLGIISALFSLVAGVILCFSCS-----PQGNRTNY-YDG------------YQAQPLATRSSP---RSAQQPKAKSEFNSYSLTGNGSTATGRQ------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88552-1", "uniprot_id": "CLD2_MOUSE", "id": "O88552-1", "name": "Claudin-2", "aln": "MASLGVQLVGYILGLLGLLGTSIAMLLPNWRTSSYVGASIVTAVGFSKGLWMECATHSTGITQCDIYSTLLGLPADIQAAQAMMVTSSAMSSLACIISVVGMRCTVFCQDSRAKDRVAVVGGVFFILGGILGFIPVAWNLHGILRDFYSPLVPDSMKFEIGEALYLGIISALFSLVAGVILCFSCS-----PQGNRTNY-YDG------------YQAQPLATRSSP---RSAQQPKAKSEFNSYSLTGYV-------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P57739-1", "uniprot_id": "CLD2_HUMAN", "id": "P57739-1", "name": "Claudin-2", "aln": "MASLGLQLVGYILGLLGLLGTLVAMLLPSWKTSSYVGASIVTAVGFSKGLWMECATHSTGITQCDIYSTLLGLPADIQAAQAMMVTSSAISSLACIISVVGMRCTVFCQESRAKDRVAVAGGVFFILGGLLGFIPVAWNLHGILRDFYSPLVPDSMKFEIGEALYLGIISSLFSLIAGIILCFSCS-----SQRNRSNY-YDA------------YQAQPLATRSSP---RPGQPPKVKSEFNSYSLTGYV-------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BHN3-1", "uniprot_id": "A0A8M2BHN3_DANRE", "id": "A0A8M2BHN3-1", "name": "", "aln": "MAILALELMGFFFGLIGMLGTLVATLLPYWATSAHVGPNIVTAVVSMKGLWMECVYQSTGAFQCETYNTLLGLTVDLQAARAMMVMSSIFSVMACAVSTVGMQCTVCMDGSSVKTKVAGVGGSMFLLAGLLSLIPVAWKTHEVVQTFYMPNMPASLKFEIGDCLYVGLASSLLSMLGGGLLSASCCDDIDGNRGSRRHYPYPERNALRGPSHSMTYQPAALHSTTNPNITNKTQTLNSHTSSGTHSIQAQDSRKMTRQNTAAGYDVTGYV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** *.::*:*:::**:*:*** :* *** * **::**..***** *******. :*** **: *.*****..*:***:**** ** :* :** :*.***:*** : * .* :** .** :*:*.*:*.:*****: * ::: ** * :* *:*****:.**:*: *:*:*::.* :*. **. : .* :* * **. .* : :.* . * : ::. .::*: . ", "identical_positions": 108, "similar_positions": 73, "identity": "40.0%" }, { "cls_id": "homologset.agr.MGI:1276111", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B0BN18-1", "uniprot_id": "PFD2_RAT", "id": "B0BN18-1", "name": "Prefoldin subunit 2", "aln": "MADSSGRVGKSGGSGTGKGAVSAEQVIAGFNRLRQEQRGLASKAAELEMELNEHSLVIDTLKEVDETRKCYRMVGGVLVERTVKEVLPALEGNKEQIQKIIETLSQQLQAKGKELNEFREKHNIRLMGEDEKPAAKENSEGAGAKSSSAGVLVS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70591-1", "uniprot_id": "PFD2_MOUSE", "id": "O70591-1", "name": "Prefoldin subunit 2", "aln": "MADSSGRVGKSGGSGAGKGAVSAEQVIAGFNRLRQEQRGLASKAAELEMELNEHSLVIDTLKEVDETRKCYRMVGGVLVERTVKEVLPALEGNKEQIQKIIETLSQQLQAKGKELNEFREKHNIRLMGEDEKPAAKENSEGAGAKASSAGVLVS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UHV9-1", "uniprot_id": "PFD2_HUMAN", "id": "Q9UHV9-1", "name": "Prefoldin subunit 2", "aln": "MAENSGRAGKSSGSGAGKGAVSAEQVIAGFNRLRQEQRGLASKAAELEMELNEHSLVIDTLKEVDETRKCYRMVGGVLVERTVKEVLPALENNKEQIQKIIETLTQQLQAKGKELNEFREKHNIRLMGEDEKPAAKENSEGAGAKASSAGVLVS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VTE5-1", "uniprot_id": "PFD2_DROME", "id": "Q9VTE5-1", "name": "Probable prefoldin subunit 2", "aln": "MSTES-----------AKPALSQEAIVAQFQQLRNEQRNLVNSLNTLEMDLREHKTVIETLEAADPERKCFRQIGGVLCERTVKEVLPQLVENKDFIAKTIQMVTNDLSKKGSELNKFKEEHNIKIRGEH-LVAEGAKGDDAEDKAENRNVLVFN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40005-1", "uniprot_id": "PFD2_YEAST", "id": "P40005-1", "name": "Prefoldin subunit 2", "aln": "------------------MEQRNNVFQAKYNEYKQILEELQTKIIELGHDKDEHTIVIKTLKDAEPTRKCYRMIGGALVESDVQTSLPILETKKENIEGTISKMKETLIQTAKEFEKWKKDNKIQVVKN--------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . * ::. :: . * .. * : **. **.**: .: ***:* :**.* * *: ** * :*: * *. :.: * ...*::::::.::*:: : ", "identical_positions": 27, "similar_positions": 41, "identity": "17.42%" }, { "cls_id": "homologset.agr.MGI:1276112", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JKD6-1", "uniprot_id": "CLD5_RAT", "id": "Q9JKD6-1", "name": "Claudin-5", "aln": "---MGSAALEILGLVLCLVGWVGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTGHMQCKVYESVLALSAEVQAARALTVGAVLLALVALFVTLTGAQCTTCVAPGPVKARVALTGGALYALCGLLALVPLCWFANIVVREFYDPTVPVSQKYELGAALYIGWAASALLMCGGGLVCCGAWVCTGRPEFSFPVKYSAP--RRTTANGDYDKKNYV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O54942-1", "uniprot_id": "CLD5_MOUSE", "id": "O54942-1", "name": "Claudin-5", "aln": "---MGSAALEILGLVLCLVGWVGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTGHMQCKVYESVLALSAEVQAARALTVGAVLLALVALFVTLTGAQCTTCVAPGPVKARVALTGGALYAVCGLLALVPLCWFANIVVREFYDPTVPVSQKYELGAALYIGWAASALLMCGGGLVCCGAWVCTGRPEFSFPVKYSAP--RRPTANGDYDKKNYV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00501-1", "uniprot_id": "CLD5_HUMAN", "id": "O00501-1", "name": "Claudin-5", "aln": "---MGSAALEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTGHMQCKVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTCVAPGPAKARVALTGGVLYLFCGLLALVPLCWFANIVVREFYDPSVPVSQKYELGAALYIGWAATALLMVGGCLLCCGAWVCTGRPDLSFPVKYSAP--RRPTATGDYDKKNYV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1R5J2-1", "uniprot_id": "F1R5J2_DANRE", "id": "F1R5J2-1", "name": "Claudin", "aln": "MANMISACLEIVGLCLTVTGTLLVMVACGLPMWKVSAFIEGNIVVAQNIWDGLWMSCVVQSTGQMQCKMHDSVLALTTDLQTARALTVISAVLGVLALMITIAGAQCTNCINTESIKSKVVNAGGVMYIVAGLFVLIPLCWMANNIISDFYDPQVPYAKKREIGAALYIGWAASAMLLVGGAILCFSR---PHDEKSTYPLKYIPPPTKGTSINGDYDKRNYV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * **.***:** * :.* :::*******:*:**:: ***.**. *.************:****:::*****::::*:****** :.:*..:**::*::*****.*: . . *::*. :**.:* ..**:.*:****:** :: :**** ** ::* *:**********:*:*: ** ::* . . . ::*:** .* : .: .*****:***", "identical_positions": 113, "similar_positions": 72, "identity": "50.67%" }, { "cls_id": "homologset.agr.MGI:1276116", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LGW0-1", "uniprot_id": "A0ABK0LGW0_RAT", "id": "A0ABK0LGW0-1", "name": "histone acetyltransferase", "aln": "MAENVVEPGPPSAKRPKLS-----------------------SPALSASASDGTDFGSLFDLEHDLP-------------DELINSTELGLTNGGDI------------SQLQTSLG-----------IVQDAAS-------KHKQLSELLRSGSSPNLNMGVGGPGQVMASQAQQN------------SPGLSLINSMVKSPMAQTGLTSPNMG-MGSSGPNQGPTQSTAGMMNSPVN--------------------------------------------QPAMGMNTGMNAGMNPGMLAAGNGQGIMPNQVMNGSIGAGRG-------RPNMQYPN---------------------AGMGNAGSLLTEPLQQGSPQMGGQPGLRGPQS---HKMGMMSNPTPYGSPYTQNSGQQIGASGLGLQIQTKTVL---------PNNLSPFAMDKKAVTGGGMPNMGQQPTPSVQQP--GLVNPVAP------GMGSG------------AHTADPEKRK-LIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKN-----------------------------------AGDKRNQQS------------------------------------ILTGAPVGLGNPSS-------------------------------------------LGVGQQSTPSLSTVSQIDPSSIERAYAALG------------LPYQVNQIPPQPPVQAKNQQSQPSGQSPQGMRSMNNMS----------------------------------------ASPMGVN-------------------------GGVG----VQTPNLLSDSMLHSTINSQNPMMNENASVASLGPLPTAAQPSSTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTR--------LQKQNMLPSAPGMVPVPMN--------------------------TAPNMGQQPTGMTTNGPLPDPSMIRGSVPNQMMPRMTPQP-----------------------------GLNQFGQMNIPQPP---------------------------------------------------------------IGPRQPSPLQHHGQLAQSGSLNPPMGYGPRMQQTSGQNQFLSQTQFPSQGMNVTNMPLAPSSSQAPVSQAQMSS-SSCPVNSPIMPPGSQGSHIHCPTLPQQA-HQNSPSPVPSRTPT-----PHHTPPSIGTQQPAATAIPAPVP--TPPAMPPGAQPQSLRPPSRQTPTPP-THLPPQVQP-----SLPVPP-ADQSQPQPRSQQSTAASVPTPTAPLLPPQPPTPLSQP-AVSVEG-----------QVSNPPS--------------------TSSTEVNSQTIPEK-----QPSQEVKMEVKMDVDQPEP----------------------------ADAQPDDTKE-----------------AKAEDGK--------VEPTETE--ERGPELKTEVKEEEDQPSTSA-----------------------------------------------AQSSPAPGQSKKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIP-----------DYFDIVKSPMDLSTIKRKLDTGQYQEPWQYIDDIWLMFNNAWLYNRKTSRVYKYCSKLSEVFEQEIDPVMQSLGYCCGRKLEFSPQTLCCYGKQLCTIPRDATYYSYQNSSPQYGLLADRYHFCEKCFNEIQGESVSLGDDPSQPQTT---------INKEQFSKRKNDTLDPELFVECTECGRKMHQICVLHHEVIWPSGFVCDGCLKKTARTRKENKFSAKRLPSTRLGTFLENRVNDFLRRQNHPESGEVTVRVVHASDKTVEVKPGMKARFVDSGEMAESFPYRTKALFAFEEIDGVDLCFFGMHVQEYGSDCPPPNQRRVYISYLDSVHFFRPKCLRTAVYHEILIGYLEYVKKLGYTTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAVSERIVHDYKDILKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERKREEN-TSNESTD--------VTKGDSKNAKKKNNKKTSKNKSSLSRGNKKKPGVPNVSNDLSQKLYATMEKHKEVFFVIRLIACPAPNSLPPIVDPDPLIPCDLMDGRDAFLTLARDKHLEFSSLRRAQWSTMCMLVELHTQSQDRFVYTCNECKHHVETRWHCTVCEDYDLCITCYNTKNHDHKMEKLGLGLDDESNNQQAAATQSPGDSRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPICKQLIALCCYHAKHCQENKCPVPFCLNIKQKLRQQQLQHRLQQAQMLRRRMASMQRTGVAGQQQG-----LPSP-----TPATPTTPTGQQPATPQTPQPQPTSQPQPTPP------------------------------------NNMTP--------------------YLPRTQTAGPVSQGKAAGQVTPPTPPQTAQPP----------LPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQR----------PIQHQM---APMAPMGMNPP-------------PMARGPGGHLDPGMGP--------AG--------MQQQPP---WAQGGMPQPQQMQS-------------------GMP---RPAMMS----------VAQHGQPLNMAPQP-----------------GLGQVGVSPLKPGTVSQQALQNLLRTLRSPSSPLQQQQVLSILHANPQLLAAFIKQRAAKYAN---------SNPQPLPGQPGMPQGQ-----PGLQPPTMPGQQG--VHSNPALQNMN--------------PMQAGVQRAGLPQQQPQQQLQPPMGGMSPQAQQMN----MNHNTMPSQFRDILRR-------------------QMMQQQ---GAGPGIGPGMANHNQFQQP-------------------------------------QGIGYPPQQQQQQQQQRMQHHMQQMQQGN--------MGQMGQLPQALGAEAGAS------------------------LQAYQQRLLQQQM-----GSPAQPN-PMSPQQHMLPNQAQ--SPHLQGQQIPNSLSN--QVRSPQPVPSPRPQSQPPHSSPSPRMQPQPSPHHVSP--QTSSPHP--------GLVAA-------------QAANPMEQGHFASPDQNSMLSQLASNPGMANLHGASATDLGLSADSADLSSNLSQSTLDIH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B2RWS6-1", "uniprot_id": "EP300_MOUSE", "id": "B2RWS6-1", "name": "Histone acetyltransferase p300", "aln": "MAENVVEPGPPSAKRPKLS-----------------------SPALSASASDGTDFGSLFDLEHDLP-------------DELINSTELGLTNGGDI------------SQLQTSLG-----------IVQDAAS-------KHKQLSELLRSGSSPNLNMGVGGPGQAMASQAQQN------------SPGLSLINSMVKSPMAQTGLTSPNMG-IGSSGPNQGPTQSPAGMMNSPVN--------------------------------------------QPAMGMNTGMNAGMNPGMLAAGNGQGIMPNQVMNGSIGAGRG-------RPNMQYPN---------------------AGMGNAGSLLTEPLQQGSPQMGGQPGLRGPQP---LKMGMMNNPSPYGSPYTQNSGQQIGASGLGLQIQTKTVL---------PNNLSPFAMDKKAVPGGGMPSMGQQPTPSVQQP--GLVTPVAA------GMGSG------------AHTADPEKRK-LIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKN-----------------------------------AGDKRNQQS------------------------------------ILTGAPVGLGNPSS-------------------------------------------LGVGQQSTPSLSTVSQIDPSSIERAYAALG------------LPYQVNQIPPQPQVQAKNQQSQPSGQSPQGMRSVNNMS----------------------------------------ASPMGVN-------------------------GGVG----VQTPNLLSDSMLHSTINSQNPMMSENAGVASLGPLPTAAQPSSTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTR--------LQKQNMLPNAPGMGPVPMN--------------------------TGSNMGQQPTGMTTNGPVPDPSMIRGSVPNHMMPRMTPQP-----------------------------GLNQFGQMNMPQPP---------------------------------------------------------------IGPRQPSPLQHHGQLAQSGSLNPPMGYGPRMQQASGQNQFLSQTQFTSQGMNVTNMPLAPSSGQAPVSQAQMSS-SSCPVNSPIMPPGSQGSHIHCPTLPQQA-HQNSPSPVPSRTPT-----PHHTPPSIGNQPPPATAIPTPVP--TPPAIPPGPQPPSLHPSSRQTPTPP-THLPPQVQP-----SLPAAPSADQSQQQPRSQQSTAVSVPTPTAPLLPPQPSTPLSQP-AVSIEG-----------QVSNPPS--------------------TSSTEVNSQTIPEK-----QPSQEVKMESKMEVDKPEP----------------------------ADAQPEDTKE-----------------AKGEDVK--------VEPTEME--ERGPELKTDGKEEEEQPSTSA-----------------------------------------------TQSSPAPGQSKKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIP-----------DYFDIVKSPMDLSTIKRKLDTGQYQEPWQYIDDIWLMFNNAWLYNRKTSRVYKYCSKLSEVFEQEIDPVMQSLGYCCGRKLEFSPQTLCCYGKQLCTIPRDATYYSYQN----------RYHFCEKCFNEIQGESVSLGDDPSQPQTT---------INKEQFSKRKNDTLDPELFVECTECGRKMHQICVLHHEIIWPSGFVCDGCLKKTARTRKENKLSAKRLPSTRLGTFLENRVNDFLRRQNHPESGEVTVRVVHASDKTVEVKPGMKARFVDSGEMAESFPYRTKALFAFEEIDGVDLCFFGMHVQEYGSDCPPPNQRRVYISYLDSVHFFRPKCLRTAVYHEILIGYLEYVKKLGYTTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAVSERIVHDYKDILKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERKREEN-TSNESTD--------VTKGDSKNAKKKNNKKTSKNKSSLSRGNKKKPGMPNVSNDLSQKLYATMEKHKEVFFVIRLIACPAPNSLPPIVDPDPLIPCDLMDGRDAFLTLARDKHLEFSSLRRAQWSTMCMLVELHTQSQDRFVYTCNECKHHVETRWHCTVCEDYDLCITCYNTKNHDHKMEKLGLGLDDESNNQQAAATQSPGDSRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPICKQLIALCCYHAKHCQENKCPVPFCLNIKQKLRQQQLQHRLQQAQMLRRRMASMQRTGVAGQQQG-----LPSP-----TPATPTTPTGQQPATPQTPQPQPTSQPQPTPP------------------------------------NNMTP--------------------YLPRTQTTGPVSQGKAPGQVTPPTPPQTAQAP----------LPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQR----------PIQHQMPQMSPMAPMGMNPP-------------PMARGPGGHLDPGIGP--------AG--------MQQQPP---WAQGGMPQPQQMQS-------------------GMP---RPAMMS----------VAQHGQPLNMAPQP-----------------GLGQVGVSPLKPGTVSQQALQNLLRTLRSPSSPLQQQQVLSILHANPQLLAAFIKQRAAKYAN---------PNPQPLPGQPGMTQGQ-----PGLQPPTMPGQQG--VHSNPALQNMN--------------PLQAGVQRAGLPQQQPQQQLQPPMGAMSPQAQQMN----MNHNTMPSQFRDILRR-------------------QMMQQQ---GAGPGIGPGMAN--QFQQP-------------------------------------QGIGYPPQQQQQQ---RMQHHMQQMQQGN--------MGQMGQLPQALGAEAGAS------------------------LQAYQQRLLQQQM-----GSPAQPN-PMSPQQHMLPNQAQ--SPHLQGQQIPNSLSN--QVRSPQPVPSPRPQSQPPHSSPSPRMQPQPSPHHVSP--QTSSPHP--------GLVAA-------------QAANPMEQGHFASPDQNSMLSQLASNPGMANLHGASATDLGLSSDNADLNSNLSQSTLDIH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q09472-1", "uniprot_id": "EP300_HUMAN", "id": "Q09472-1", "name": "Histone acetyltransferase p300", "aln": "MAENVVEPGPPSAKRPKLS-----------------------SPALSASASDGTDFGSLFDLEHDLP-------------DELINSTELGLTNGGDI------------NQLQTSLG-----------MVQDAAS-------KHKQLSELLRSGSSPNLNMGVGGPGQVMASQAQQS------------SPGLGLINSMVKSPMTQAGLTSPNMG-MGTSGPNQGPTQSTG-MMNSPVN--------------------------------------------QPAMGMNTGMNAGMNPGMLAAGNGQGIMPNQVMNGSIGAGRG-------RQNMQYPN---------------------PGMGSAGNLLTEPLQQGSPQMGGQTGLRGPQP---LKMGMMNNPNPYGSPYTQNPGQQIGASGLGLQIQTKTVL---------SNNLSPFAMDKKAVPGGGMPNMGQQPAPQVQQP--GLVTPVAQ------GMGSG------------AHTADPEKRK-LIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKN-----------------------------------AGDKRNQQP------------------------------------ILTGAPVGLGNPSS-------------------------------------------LGVGQQSAPNLSTVSQIDPSSIERAYAALG------------LPYQVNQMPTQPQVQAKNQQNQQPGQSPQGMRPMSNMS----------------------------------------ASPMGVN-------------------------GGVG----VQTPSLLSDSMLHSAINSQNPMMSENASVPSLGPMPTAAQPSTTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTR--------LQKQNMLPNAAGMVPVSMN--------------------------PGPNMGQPQPGMTSNGPLPDPSMIRGSVPNQMMPRITPQS-----------------------------GLNQFGQMSMAQPP---------------------------------------------------------------IVPRQTPPLQHHGQLAQPGALNPPMGYGPRMQQPSNQGQFLPQTQFPSQGMNVTNIPLAPSSGQAPVSQAQMSS-SSCPVNSPIMPPGSQGSHIHCPQLPQPALHQNSPSPVPSRTPT-----PHHTPPSIGAQQPPATTIPAPVP--TPPAMPPGPQSQALHPPPRQTPTPPTTQLPQQVQP-----SLPAAPSADQPQQQPRSQQSTAASVPTPTAPLLPPQPATPLSQP-AVSIEG-----------QVSNPPS--------------------TSSTEVNSQAIAEK-----QPSQEVKMEAKMEVDQPEP----------------------------ADTQPEDISE-----------------SKVEDCK--------MESTETE--ERSTELKTEIKEEEDQPSTSA-----------------------------------------------TQSSPAPGQSKKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIP-----------DYFDIVKSPMDLSTIKRKLDTGQYQEPWQYVDDIWLMFNNAWLYNRKTSRVYKYCSKLSEVFEQEIDPVMQSLGYCCGRKLEFSPQTLCCYGKQLCTIPRDATYYSYQN----------RYHFCEKCFNEIQGESVSLGDDPSQPQTT---------INKEQFSKRKNDTLDPELFVECTECGRKMHQICVLHHEIIWPAGFVCDGCLKKSARTRKENKFSAKRLPSTRLGTFLENRVNDFLRRQNHPESGEVTVRVVHASDKTVEVKPGMKARFVDSGEMAESFPYRTKALFAFEEIDGVDLCFFGMHVQEYGSDCPPPNQRRVYISYLDSVHFFRPKCLRTAVYHEILIGYLEYVKKLGYTTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAVSERIVHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERKREEN-TSNESTD--------VTKGDSKNAKKKNNKKTSKNKSSLSRGNKKKPGMPNVSNDLSQKLYATMEKHKEVFFVIRLIAGPAANSLPPIVDPDPLIPCDLMDGRDAFLTLARDKHLEFSSLRRAQWSTMCMLVELHTQSQDRFVYTCNECKHHVETRWHCTVCEDYDLCITCYNTKNHDHKMEKLGLGLDDESNNQQAAATQSPGDSRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPICKQLIALCCYHAKHCQENKCPVPFCLNIKQKLRQQQLQHRLQQAQMLRRRMASMQRTGVVGQQQG-----LPSP-----TPATPTTPTGQQPTTPQTPQP--TSQPQPTPP------------------------------------NSMPP--------------------YLPRTQAAGPVSQGKAAGQVTPPTPPQTAQPP----------LPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQR----------PIQHQMPPMTPMAPMGMNPP-------------PMTRGPSGHLEPGMGP--------TG--------MQQQPP---WSQGGLPQPQQLQS-------------------GMP---RPAMMS----------VAQHGQPLNMAPQP-----------------GLGQVGISPLKPGTVSQQALQNLLRTLRSPSSPLQQQQVLSILHANPQLLAAFIKQRAAKYAN---------SNPQPIPGQPGMPQGQ-----PGLQPPTMPGQQG--VHSNPAMQNMN--------------PMQAGVQRAGLPQQQPQQQLQPPMGGMSPQAQQMN----MNHNTMPSQFRDILRRQ------------------QMMQQQQQQGAGPGIGPGMANHNQFQQP-------------------------------------QGVGYPPQQQQ-----RMQHHMQQMQQGN--------MGQIGQLPQALGAEAGAS------------------------LQAYQQRLLQQQM-----GSPVQPN-PMSPQQHMLPNQAQ--SPHLQGQQIPNSLSN--QVRSPQPVPSPRPQSQPPHSSPSPRMQPQPSPHHVSP--QTSSPHP--------GLVAA-------------QAN-PMEQGHFASPDQNSMLSQLASNPGMANLHGASATDLGLSTDNSDLNSNLSQSTLDIH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AQU5-1", "uniprot_id": "A0A8M3AQU5_DANRE", "id": "A0A8M3AQU5-1", "name": "histone acetyltransferase", "aln": "MADNVLDSGPPTAKRPKLS-----------------------SPALSVSASDGNDFGSLFDLEHDLP-------------DELINSSDLGLPNGMDP------------SQLHTSLG-GGGMSGPLGVSGQDTAA-------KHKHLSELLRPGAPP-------SAST--ATGSPGN------------AASLGMMGGLSGGPVTQG------MGGPQQ-----QPSMMPQPGMVGGLN--------------------------------------------RAMMGTQKGN--GQPQ---------SMMGGQMMNGAPRMGYA-------NVNMNAGM---------------------AGNGNMLPDSLQQPNAGQQMA--QAAMRPQQPGAVNKMGMMGAPGPYGGSYGQCGGQ----SQLGPQLQNKAGQ---------PNSINQFNMDKKPQLGQNMGGMQGP----------GVVGGVS-------GPGGT----------AAPPAADPEKRK-LIQQQLVLLLHAHKCHRREQANGEVRQCNLPHCRTMKNVLNHMTHCQAGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKS-----------------------------------AGDKRNQQS------------------------------------LLGGAGMAMGGPLGG-----------------------------------------SLPGGQPSAPNINPPSQIDPSSIERAYAALG------------LTYQGNQASNQN--------QQTSVPGQPGMRSLNNMAG---------------------------------------GNSMGVN-------------------------GGVGAPMSNQHPGMLPDGMLHRNMTAQS-LMNDSSGVGNMGSAATATPPSAG-MRKSWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEGDMYESANSRAEYYHLLAEKIYKIQKELEEKRRTR--------LQKQ-------------------------------------------------------DGPHSDPSLVQATGPSQMVNRMQNPAG----------------------MPHSLNGMNQFGQVGMQQP----------------------------------------------------------------MGQRATPPLPMGANLNQMSMQGTPRMAQPNVPQLQNQYMQN-QFTGTGAGLGQGAVGLNQPAGQGAMPQNQMPTPPSLSVHSPVAQSQSS-VPVSGAAAGPQGPPSNHPPPAPQPGLH-----THCPPLRQNSPSPARSLTPTPAPHQTPPQLPGNQTPQPHTPNSSTTMAPPASQLPPMAQGVASEKSSQLQQQSHGGGATGGPQTGLASSVPSQNAHGLCTHPHSPLSQKSSATVDG-----------QASTPAS--------------------VSSADPSSQLTSSEPTAPLDSKTEVKQQDEEEENENETEDKASGKMAA----------------MQTEIKSEEKPE-----------------IKKEEPAGDECKTEPMETSTAE--DKKPEVKTEPKEEEVAGANST-----------------------------------------------PANTQS----KKKEFKPDELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPVRIRTSNKTNLDYFDIVKNPIDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKYCSKLAEVFEQEIDPVMQELGYCCGRKLEFSPQTLCCYGKQLCTIPRDAAYFSYQNSSPKYGLLADRYHFCEKCFNEIQGENVSLGDDPTQPQTS---------INKDQFQRKKNDTLDPELLLECGDCGRKMHQICVLHNETIWPSGFICDGCLKKSNSTRKENKYAAKRLPQTKLGNFLETRVNDYLKRQNHPESGEVTIRVVHISDKVVEVKPGMKSRFVDSGEMSESFPYRTKALFAFEEIDGTDVCFFGMHVQEYGSDCPPPNQRRVYISYLDSVHFFQPRHLRTGVYHEILIGYLEYVKKMGFVMGHIWACPPSEGDDYIFHCHPSDQKIPKPKRLQEWYKKMLDKAVTERIVHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERKREENNTSSESID--------ATNGDSKNAKKKNNKKTSKNKSSLSRANKKKPGMPNVSNDLSQKLYATMEKHKEVFFVIRFIAGPAANSLPPISDPDTLMACDLMDGRDAFLTLARDKHLEFSSLRRAKWSSMCMLVELHNQTQDRFVYTCNECKHHVETRFHCTVCEDYDLCITCYNVKGHEHKMEKLGLGLDDESNNQAAASTQNPGDSRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPICKQLIALCCYHAKHCQETKCPVPFCLNIKHKLRQQQLQHRLQQAQMLRRRMATMQRVGQPPPCGGGPPGGLPSPGNNGATGPSTPTSVGTQPATPQTPTQLTPNLISLPQPGAGGVPAGAPQQSPQHPVHHQFQQMPGAGGMMNSQQQQMVPQQSLGQVPHPHNQYG-------PHPTGPSPNTQSQGKPGLGPATPPQLPSNPGTVPMAQQQQPTGPPAAAVEIAMKIQQVADAQRKMAQVQLLQRQAAQAGMM--PQH--HQ--QPQGQIGVAHPGIGMVGPQGLASQAQTSANRVQMEQQQGPQG---MMGAGP-------MQQQQPQQVAVQGQMPPQMHPQQPRMNPPL-QPQ-QQQWPGQGMPTQQRPAMMSQQGMVSMQ-PQPQPQQPSQQTQQQQAPQMPNRNALMSMVQAGLQSGVASGAAASNLPQGALQQLLRTLRSPSSPQQQQQVLNILRSSPLLMAAFIKQRVHKYKG-------GTGGPSGPQGGPGPMGGQPVGVNTGVPQPGMHLGQG--VNMQSQLLSQQQSQQQQQ---MQQRPLLQQQQVAALQQQQQQQQQQQQQQQQQQHQQQQQQ---QQHQQQQQQQQGIQGQGTPNMANPHFRELVMRRQQQLQFQQQQQQQQQQQQQQMSNHAAFQ-----QQQGYMSQQGNMQVPPGG-------QPLQGVQPGQQQNFPGNPAQQQAAAALQQRLAQQQHQL--------QMQQQQNAATQGPDMGPGGGPQPTQLGPGLQSP-----QALLQQALHQRLFPQQQ-HLSGTSPAQQNNPMSPQQ---QQISQ--SPHLQGQQLPSSLSN--QVCSPQ--PSPRPQSQPPHSSPSPRLQPQPSPHHISPQTQTGSPHPSHLQQHHSGMAPPPPPHQ-------QPQHNSKDPSGFG-ADQNAMLSQLS---GMAGLHGPGANDM-LPPSGQDLGINMNLTL----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M3BE71-1", "uniprot_id": "A0A8M3BE71_DANRE", "id": "A0A8M3BE71-1", "name": "histone acetyltransferase", "aln": "MAENVLDSGPPSAKRPKLS-----------------------SPALSASASDGNDFGSLFDLEHDLP-------------DELISSSELSLANGGDL------------SQLHTSLGSGGGVIGGAVSGGQDAAA-------KHRQLSELLRHGSTP-------GAQQQGAMGNPG-------------GASMGLFGNMKVSPGTQS------MGPQGQQHLSMQAGLMQQQQMVDYLN--------------------------------------------RNMLGPQKGN--GQQQPGGPAPQHQNALASQMMNGSPRIGHH-------NPGMGN------------------------SNSNLLAEALQQQQQQQQTVGSQGGLRPQQPGAISKMGINAGSGPYGGPYSQSASQGLGVAGLAPQLQNKPGL---------PNSPAQFNLDKKPLPIHGIPGMQASQSSPVGAGGGGVAAGMVPNAQGSLGPGSAGSVVSAAVVGGVPPAADPEKRK-LIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQAGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKN-----------------------------------AGDKRNQQSE----------------------------------SMIATGGVALSSSMG------------------------------------------NVTGGSPSAPSLNTPGQIDPSSIERAYAALG------------LTYQGNQAPPQ--------------PVQQTQRPVNTMG----------------------------------------ANSMGVN-------------------------GAVGGQSQNQQSSLLQDTMLHLNMNSQS-LINDS-GVG---SLPMANPAASGSMRKSWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEGDMYESANSRAEYYHFLAEKIYKIQKELEEKRRTR--------LQKQGIMPSQAGMNPSGLQQAT-----------------------TGIGQPGPPTGLPSNGPLSDPAVVRPTGPNQMMNRMQNTA-----------------------------GMNSFGNHMGMQS----------------------------------------------------------------MGQRSTPPLNQGS-------MVPGRMPQPNVAQMQNQYMQTGPFQASSPVRSAGPVDLVHGGNDGAATQQGQMPLSSLPVGSPLAQPGSAGGAGSGSSVGSLGPSSMSAVPPSSTPTHSISL-SHCPPVHQNSPSPAHSRTPTPT--------PGSQTPQPHTPS-----------LPHLSSNGSQQQFPPSASSDSGMQPLGTPPAVSHSGLSTPNAS---QHPRTPLSHKGSLPVDG-----------QAATPAS--------------------VSSVEASFQQAPSDSTATLEPKEEVKAKDEEEEEAMEEERTAK----------------------EEDSKPEEKPE-----------------VKKEEPLSDGG---PMETASDE--DKKPEIKIEPKEEEEGSESAT-----------------------------------------------SQSSVSGATNKKKIFKPEELRQALMPTLESLYRQDPESLPFRQPVDPSLLGIP-----------DYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDIWLMFNNAWLYNRKTSRVYKYCSKLAEVFEQEIDPVMQSLGYCCGRKLEFSPQTLCCYGKQLCTIPRDAAYFSYQNSSPKYGLLADRYHFCEKCFNEIQGETVSLGDDPSQPQTATIFLNISRSINKDQFEKKKNDTLDPELFVECMDCGRKMHQICVLHNETIWPSGFVCDGCLKKSNKTRKENKYAAKRLPQTKLGNFLETRVNAYLKRQNHPESGEVTVRVVHVSEKMVEVKPGMKSRFVDSGEMSESFPYKSKALFAFEEIDGVDVCFFGMHVQEYGSDCPPPNQRRVYISYLDSVHFFQPRFLRTEVYHEILIGYLDYAKRQGFTTGHIWACPPSEGDDYIFHCHPADQKIPKPKRLQEWYKKMLDKAVAERVVHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERKREENSTSNESVE--------TTKGDSKNAKKKNNKKTSKNKSSLSRGNKKKPGMPNVSNDLSQKLYATMEKHKEVFFVIRLFAAPNSNALLPIVDPDPLMACDLMDGRDAFLTIARDKHLEFSSLRRSKWSTMCMLVELHNQSQDRFVYTCNECKHHVETRFHCTVCEDYDLCITCYNTKGHEHKMDKLGLGLDDESNSQVASTTQNPGDSRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPICKQLIALCCYHAKHCQENKCPVPFCLNIKQKLRQQQLQHRLQQAQMVRRRMASMQRTGQQLPGGG---CGLPSPGNGCNTGPSTPTPS-TQPPTPQTPNQQCQ--PPATQPGVGNVPS--QQQQQLAGMAHQYQPISGSGGMINSSQQSMLPQQQQQPTPAQHLQNANNLPPYVQRPTGSSPHSQSMGKPGMVPGGFSQQQQSNLGQPVMPQHQPPGPPPAAVEIAMKIQRVAETQRQMAQQKILQRNQAPG-MM--PPHGLHQGPQTQNQMGINLPGTAMVGP----SQAQVAVARNQMDQQQG------MVTAG--------MQQQQP---GPRSQLPQVQLQQGQQGAPQL-QVSPQQQWTGPGMPPQQRPGVMNQMGLQGMAAPQHQQQQAVGQSQPQ------GNSGVMGMISS-QGGAAPAGAGPGNHSQAALQDLLRFLRLPSSPHQQQQVLSILRSNPLLMATFIRQRAPRYLGRGGPGAGGAGVPGGPGGGPGIMDGQQMNVNPNAAQGGMHMTQG--TTMQMNPLQQQQQQQQIQQRPMMSGNLQQQQQMAVLQQQQQQGVMPSQGTNISNIPPQLRE---MMRRHLQQQQQQQQQQ-----------------QQQQQQQQQQQQQQQQQHQQMGNHAQFQHPQPPQQQGYLGQSGIPPQQPGQPHPGGLQQQQGGAQPGTQQNYSGSVSHQQVAAALQHSLQQQQLQM--------QQQQSAMGGYQGADGGPGGGGPLQQQQQQMQSAPMGSQPQMFQQAIQQRLLQQQQSHLGGGSPAQHN-PMSPQQSQ-QQMSQ--SPHLQG-QLPNSLGN--QVRSPQ--PSPRPQSQPPNSSPSPRLQPQPSPHHISP--QTGSPHPGHLPQHHSGMAAPPPPQQQAQASQQQQQVNAMDQGPFG-ADQNVLLSQLS---GMGALHGQGTNDM-LTNN-QDMGSNINHSLDLM-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9MS40-1", "uniprot_id": "M9MS40_DROME", "id": "M9MS40-1", "name": "histone acetyltransferase", "aln": "MMADHLDE--PPQKRVKMDPTDISYFLEENLPDELVSSNSGWSDQLTGGAGGGNGGGGASGVTTNPTSGPNPGGGPNKPAAQGPGSGTGGVGVGVNVGVGGVVGVGVVPSQMNGAGGGNGSGTGGDDGSGNGSGAGNRISQMQHQQLQHLLQQQQQGQKGAMVVPGMQQLGSKSPNLQSPNQGGMQQVVGTQMGMVNSMPMSISNNGNNGMNAIPGMNTIAQGNLGNMVLTNSVGGGMGGMVNHLKQQPGGGGGGMINSVSVPGGPGAGAGGVGAGGGGAVAANQGMHMQNGPMMGRMVGQQHMLRGPHLMGASGGAGGPGNGPGGGGPRMQNPNMQMNFRPFAAQLNSLPYGVGQYGGPGGGNNPQQQQQQQQQQLLAQQMAQRGGVVPGMPQGNRPVGTVVPMSTLGGDGSGPAGQLVSGNPQQQQMLAQQQTGAMGPRPPQPNQLLGHPGQQQQQQQQPGTSQQQQQQQGVGIGGAGVVANAGTVAGVPAVAGGGAGGAVQSSGPGGANRDVPDDRKRQIQQQLMLLLHAHKCNRRENLNPNREVCNVNYCKAMKSVLAHMGTCKQSKDCTMQHCASSRQILLHYKTCQNSGCVICYPFRQNHSVFQNANVPPGGGPAGIGGAPPGGGGAGGGAAGAGGNLQQQQQQQQQQQQNQQPNLTGLVVDGKQGQQVAPGGGQNTAIVLPQQQGAGGAPGAPKTPADMVQQLTQQQQQQQQQVHQQQVQQQELRRFDGMSQQVVAGGMQQQQQQGLPPVIRIQGAQPAVRVLGPGGPGGPSGPNVLPNDVNSLHQQQQQMLQQQQQQGQNRRRGGLATMVEQQQQHQQQQQQPNPAQLGGNIPAPLSVNVGGFGNTNFGGAAAGGAVGANDKQQLKVAQVHPQSHGVGAGGASAGAGASGGQVAAGSSVLMPADTTGSGNAGNPNQNAGGVAGGAGGGNGGNTGPPGDNEKDWRESVTADLRNHLVHKLVQAIFPTSDPTTMQDKRMHNLVSYAEKVEKDMYEMAKSRSEYYHLLAEKIYKIQKELEEKRLKRKEQHQQMLMQQQGVANPVAGGAAGGAGSAAGVAGGVVLPQQQQQQQQQQQQQGQQPLQSCIHPSISPMGGVMPPQQLRPQGPPGILGQQTAAGLGVGVGVTNNMVTMRSHSPGGNMLALQQQQRMQFPQQQQQQPPGSGAGKMLVGPPGPSPGGMVVNPALSPYQTTNVLTSPVPGQQQQQQFINANGGTGANPQLSEIMKQRHIHQQQQQQQQQQQQGMLLPQSPFSNSTPLQQQQQQQQQQQQQQQATSNSFSSPMQQQQQGQQQQQQKPG--SVLNNMPPTPTSLEALNAGAGAPGTGGSASNVTVSAPSPSPGFLSNGPSIGTPSNNNNNSSANNNPPSVSSLMQQPLSNRPGTPPYIPASPVPATSASGLAASSTPASAAATCASSGSGSNSSSGATAAGASSTSSSSSAGSGTPLSSVSTPTSATMATSSGGGGGGGGNAGGGSSTTPASNPLLLMSGGTAGGGTGATTTTSTSSSSRMMSSSSSLSSQMAALEAAARDNDDETPSPSGENTNGSGGSGNAGGMASKGKLDSIKQDDDIKKEFMDDSCGGNNDSSQMDCSTGGGKGKNVNNDGTSMIKMEIKTEDGLDGEVKIKTEAMDVDEAGGSTAGEHHGEGGGGSGVGGGKDNINGAHDGGATGGAVDIKPKTETKPLVPEPLAPNAGDKKKKCQFNPEELRTALLPTLEKLYRQEPESVPFRYPVDPQALGIP-----------DYFEIVKKPMDLGTIRTNIQNGKYSDPWEYVDDVWLMFDNAWLYNRKTSRVYRYCTKLSEVFEAEIDPVMQALGYCCGRKYTFNPQVLCCYGKQLCTIPRDAKYYSYQNSLKEYGVASNRYTYCQKCFNDIQGDTVTLGDDPLQSQTQ---------IKKDQFKEMKNDHLELEPFVNCQECGRKQHQICVLWLDSIWPGGFVCDNCLKKKNSKRKENKFNAKRLPTTKLGVYIETRVNNFLKKK-EAGAGEVHIRVVSSSDKCVEVKPGMRRRFVEQGEMMNEFPYRAKALFAFEEVDGIDVCFFGMHVQEYGSECPAPNTRRVYIAYLDSVHFFRPRQYRTAVYHEILLGYMDYVKQLGYTMAHIWACPPSEGDDYIFHCHPTDQKIPKPKRLQEWYKKMLDKGMIERIIQDYKDILKQAMEDKLGSAAELPYFEGDFWPNVLEESIKELDQEEEEKRKQAEAAEAAAAANLFSIEENEVSGDGKKKGQKKAKKSNKSKAAQ-RKNSKKSNEHQSGNDLSTKIYATMEKHKEVFFVIRLHSAQSAASLAPIQDPDPLLTCDLMDGRDAFLTLARDKHFEFSSLRRAQFSTLSMLYELHNQGQDKFVYTCNHCKTAVETRYHCTVCDDFDLCIVCKEKVGHQHKMEKLGFDIDDGS-ALADHKQANPQEARKQSIQRCIQSLAHACQCRDANCRLPSCQKMKLVVQHTKNCKRKPNGGCPICKQLIALCCYHAKNCEEQKCPVPFCPNIKHKLKQQQSQQKFQQQQLLRRRVALMSRTAAPAALQG--PAAVSGP-----TVVSGGVPVVGMSGVAVSQQVIPGQAGILPPG-----------------------------------AGGMSP----------------------STVAVPSPVSGGAGAGGMGGMTSPHPHQPGIG---MKPGGGHSPSPNVLQVVKQVQEEAARQQVSHGGGFGKGVPMAPPVMNRPMGGAGPNQNVVNQLGGMGVGVGGVGGVG--VGGVGGVGVNQLNSGGGNTPGAPISGPGMNVNHLMSMDQWGGGGAGGGGANPGGGNPQARYANNTGGMRQPTHVMQTNLIPPQQQQQMMGGLGGPNQLGGGQMPVGGQHGGMGMGMGAPPMAGTVGGVRPSPGAGGGGGSATGGGLNTQQLALIMQKIKNNPTNESNQHILAILKQNPQIMAAIIKQRQQSQNN--------AAAGGGAPGPGGALQQQQAGNGPQNPQQQQQQQQQQQVMQQQQMQHMMNQQQGGGGPQQMNPNQQQQQQQVNLMQQQQQGGPGGPGSGLPTRMPNMPNALGMLQSLPPNMSPGVSTQG---------GMVPNQNWNKMRYMQMSQYPPPYPQRQRGPHMGGAGPGPGQQQFPGGGGGAGNFNAGGAGGAGGVVGVGGVPGGAGTVPGGDQYSMANAAAASNMLQQQQGQVGVGVGVGVKPGPGQQQQQMGVGMPPG----------------------MQQQQQQQQPLQQQQMMQVAMPNANAQNPSAVVGGPNAQVMGPPTPHSLQQQLMQSARSSPPIRSPQPTPSPRS-APSPRAAPSASPRAQPSPHHVMS---SHSPAPQGPPHDG------------------MHNHGMHHQSPLPGVPQDVGVGVGVGVGVGVNVNVGNVGVGNAGGALPDASDQLTKFVERL-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : :: *. ** *:. * *: .*..*.. *. .: : . : .* .: * : .*:: : * :.:.: :*::*..**: . .. :.:...: . : : : . :. . : :.* * : . *. * . .* . . : : : .: . :* . *. .* *: : .*. . ::: . *:. *. . *:.** *****:********:***: * : . **: :*::**.** ** *: .*.* : ********: *:*.* . .* :* *::. **.: :** :: . ... . : * . . . * .. : * .** *. : *. * .: ...:*.* .... ..:* .: . . . . . .. .*.*:*.:* *****************.**::::*:**.***:**.*** **** *:.*:****:**************** .* :*:* * * :: * :: : .* : *. : * .. . * . :. * * * . . . . . .. . . . .. . *... . . . * . . . .: : :* * : . * . :.*.* .*: . . ... . *. . : : : : : : * :: :* : : ::* : : : .:: . . : ** *:*:*** **:**** ****:***:*** ****. **** ***:***.*:**.**: :::.*:*.:**:*:**:****:*************:**:**:**** ******* ******** *.**.*************** *:**** ** :*:****:***:.*:***** *.** *:*:**.. *** *: * :::* :**** ****** : ***.**:**.****. .***** ***** *:** ::*.*** :*::: .. :*** :*** *:* *******: ***:.*** :.***::********:** *:************:**.** *****:********:*: ** ******:**::*.*: *:. .*******************.********************.: **:::*****:*** **:* ** *********************:*****:::: : :. : ..**.*: :*: **:.*.*:: * *.**.. : .**** *:***************: : . :* ** ***.*:.************:*****:*******:::*::.** ***.* **:******.** ****:*****:*:****.* : .*:***:***:.:** * .* ::*: *********.******:*** ******** ******.****.*******************:*:* ******* ***:**:*** *:::** *::***:* *.*.. * :..* * : .. . .. : . * * ..* : . . : .: . .*.. .:::. ::*. * *: : : * :* ::: * .* *:* . * * :* : :*. . . * ::: :: .: .:*::* **: .* ::*::*:** . * * * . * . : * . * *** * : : . : : * . . .: : * * * .. * :*: : ** . .: : * : : :** *: .* . : *** ****. : .*.::**. :.******: . : ** * . . : *: :. :: .. * . ::. ", "identical_positions": 777, "similar_positions": 548, "identity": "22.59%" }, { "cls_id": "homologset.agr.MGI:1276121", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q00972-1", "uniprot_id": "BCKD_RAT", "id": "Q00972-1", "name": "Branched-chain alpha-ketoacid dehydrogenase kinase", "aln": "--------MILTSVLGSG-----------PRSGSSLWPLLGSS-LSLRVRSTSATDTHHVELARERSKTVTSFYNQSAIDVVAEKPSVRLTPTMMLYSGRSQDGS--HLLKSGRYLQQELPVRIAHRIKGFRSLPFIIGCNPTILHVHELYIRAFQKLTDFPPIKDQADEAQYCQLVRQLLD--DHKDVVTLLAEGLRESRKHIEDEKLVRYFLDKTLTSRLGIRMLATHHLALHEDKPD-------FVGIICTRLSPKKIIEKWVDFARRLCEHKYGNA---PRVRINGHVAARFPFIPMPLDYILPELLKNAMRATMESHLDTPYNVPDVVIT-IANNDVDLIIRISDRGGGIAH-------------------------------KDLDRVMDYHFTTAEASTQDPRISPLFGHLDMHSGGQSGPMHG-------------------FGFGLPTSRAYAEYLGGSLQLQSLQGIGTDVYLRLRHIDGREESFRI---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O55028-1", "uniprot_id": "BCKD_MOUSE", "id": "O55028-1", "name": "Branched-chain alpha-ketoacid dehydrogenase kinase", "aln": "--------MILTSVLGSG-----------PRSWSSLWPLLGSS-LSLRARSTSATDTHHVELARERSKTVTSFYNQSAIDVAAEKPSVRLTPTMMLYSGRSQDGS--HLLKSGRYLQQELPVRIAHRIKGFRSLPFIIGCNPTILHVHELYIRAFQKLTDFPPIKDQADEAQYCQLVRQLLD--DHKDVVTLLAEGLRESRKHIQDEKLVRYFLDKTLTSRLGIRMLATHHLALHEDKPD-------FVGIICTRLSPKKIIEKWVDFARRLCEHKYGNA---PRVRINGHVAARFPFIPMPLDYILPELLKNAMRATMESHLDTPYNVPDVVIT-IANNDIDLIIRISDRGGGIAH-------------------------------KDLDRVMDYHFTTAEASTQDPRINPLFGHLDMHSGGQSGPMHG-------------------FGFGLPTSRAYAEYLGGSLQLQSLQGIGTDVYLRLRHIDGREESFRI---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14874-1", "uniprot_id": "BCKD_HUMAN", "id": "O14874-1", "name": "Branched-chain alpha-ketoacid dehydrogenase kinase", "aln": "--------MILASVLRSG-----------PGGGLPLRPLLGPA-LALRARSTSATDTHHVEMARERSKTVTSFYNQSAIDAAAEKPSVRLTPTMMLYAGRSQDGS--HLLKSARYLQQELPVRIAHRIKGFRCLPFIIGCNPTILHVHELYIRAFQKLTDFPPIKDQADEAQYCQLVRQLLD--DHKDVVTLLAEGLRESRKHIEDEKLVRYFLDKTLTSRLGIRMLATHHLALHEDKPD-------FVGIICTRLSPKKIIEKWVDFARRLCEHKYGNA---PRVRINGHVAARFPFIPMPLDYILPELLKNAMRATMESHLDTPYNVPDVVIT-IANNDVDLIIRISDRGGGIAH-------------------------------KDLDRVMDYHFTTAEASTQDPRISPLFGHLDMHSGAQSGPMHG-------------------FGFGLPTSRAYAEYLGGSLQLQSLQGIGTDVYLRLRHIDGREESFRI---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0R159-1", "uniprot_id": "B0R159_DANRE", "id": "B0R159-1", "name": "Protein-serine/threonine kinase", "aln": "--MRGRVTGQAMELLGSGGCRISVTRLFLSPSAKAAAPVTGAHGVGRRFRSTSSMSS-YSELARERSKTVTSFYNQSAIDASAEKPSVRLTPATMLYAGKSPDGQ--HILSSARYLHKELPVRIAHRIKGFRSLPFIIGCNPTILQVHELYIRAYHMLSDFPAIQDQETEARYSKMVKQLLD--DHKDVVTMLAEGFRECRKHILDEMLVRNFLDTTLTSRLGIRMLATHHIALHEDNPD-------FVGIICRRLSPKKIIEKWVDFARRLCEHQYGNS---PRVRINGHVAARFPFIPLPLDYILPELLKNAMRATMESHLDTPYNVPDVVVT-IANNDTDFVIRISDRGGGIPH-------------------------------SILDKVMHYHFSTAEQSAQDPRMSNLFDSMTN-SGPQSGPMHG-------------------FGFGLPTSRAYAEYLGGSLAIQSMQGIGTDVYLRLRHIDGKGESFRV---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P40530-1", "uniprot_id": "PDK1_YEAST", "id": "P40530-1", "name": "[Pyruvate dehydrogenase (acetyl-transferring)] kinase 1, mitochondrial", "aln": "-------MWKIMRSWKCG----------------------GMR----WAHRQRPSHELLSQLSFDQHYKIRSNIELLIQDYASKPIAPLNYEYFLQYRPPLTKKE--EYMLTIKTINLLLSL-TCKRLNAIQRLPYNAVINPHIERTNSLYLKSLQTLLSIAYPYELHNPPKIQAKFTELLD--DHEDAIVVLAKGLQEIQSCYP-KFQISQFLNFHLKERITMKLLVTHYLSLMAQNKGDT--NKRMIGILHRDLPIAQLIKHVSDYVNDICFVKFNTQR-TPVLIHPPSQDITFTCIPPILEYIMTEVFKNAFEAQIALGKEH---MPIEINL-LKPDDDELYLRIRDHGGGITP-------------------------------EVEALMFNYSYSTHTQQSADSESTDLP-------GEQINNVSG-------------------MGFGLPMCKTYLELFGGKIDVQSLLGWGTDVYIKLKGPSKTALLSKK---", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P53170-1", "uniprot_id": "PDK2_YEAST", "id": "P53170-1", "name": "[Pyruvate dehydrogenase (acetyl-transferring)] kinase 2, mitochondrial", "aln": "MSKYQINCIRYRHFLRTSN---------ISQIPDFTKYCIGPVNEELAPYIMETMKAYPSNSEYINPQHYYHNRTVLVENYLKRSPNPVSLTQLAQYYDDSTKLTRTKIINSGKFVKEELVIRIAHKLNQLQQLPFNVVNNFHFVQVYESYYNIFESFRKYPTIRTLEDASQFADFIKNMLEGFNTLNLPHLIMGALECTILDLYPREKMDQLLSDLLRARISRRLIVEEHVSITANYTSGKEENTLVLGDIFQECSAKKYLLEASEESQKFIQDMYFKDIPMPEFIIEGDTQLSFYFLPTHLKYLLGEILRNTYEATMKHYIRKGLEKPEPIIVTVVSNDESYLFRISDKAGGVLHDDENLWSFGKSKERAQESLNNFHKLPGLQTVSIYDEVHSHTKYNSKLKSLQSITLKPYMHTSLEPMSYPSIINGHIKYETPLIELLKRSFRYKLGIGLAMCKVYAEYWNGDLSLHSMPGYGTDVVLKLGNLMKHTKKLQLDKV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * . : . : . * . . : : : :: * : .:::: :: **: * : :. . * . . : . . .: . ::*: : : :: .:. . : :*. * *: :::. .:::: : . .:* : . : : . : . : : . * . * :* *.*:: *:::*: .* : * : : :* . :** *:.**: . : : . .: :. . : * :*:**. .:.* * .*.: ::*: * **** ::* : ", "identical_positions": 41, "similar_positions": 116, "identity": "8.2%" }, { "cls_id": "homologset.agr.MGI:1276123", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P55090-1", "uniprot_id": "UCN1_RAT", "id": "P55090-1", "name": "Urocortin", "aln": "MRQRGRATLLVALLLLVQLRPESSQWSPAAAAANVVQDPNLRWNPGVRNQGGGVRALL----LLLAERFPRRAGSE-----PAGER---------QRRDDPPLSIDLTFHLLRTLLELARTQSQRERAEQNRIIFDSVGK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P81615-1", "uniprot_id": "UCN1_MOUSE", "id": "P81615-1", "name": "Urocortin", "aln": "MIQRGRATLLVALLLLAQLRPESSQWSPAAAAATGVQDPNLRWSPGVRNQGGGVRALL----LLLAERFPRRAGSE-----PAGER---------QRRDDPPLSIDLTFHLLRTLLELARTQSQRERAEQNRIIFDSVGK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P55089-1", "uniprot_id": "UCN1_HUMAN", "id": "P55089-1", "name": "Urocortin", "aln": "MRQAGRAALLAALLLLVQLCPGSSQRSPEAAG---VQDPSLRWSPGARNQGGGARALL----LLLAERFPRRAGPGRLGLGTAGER---------PRRDNPSLSIDLTFHLLRTLLELARTQSQRERAEQNRIIFDSVGK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5TZ50-1", "uniprot_id": "Q5TZ50_DANRE", "id": "Q5TZ50-1", "name": "", "aln": "-MKPVPLVLLITSVLLSHI-PLSFCRPRDLNSLHNQLDDLLLGRPGGGGGGDAMSVLMGEKLLQYLQRSAQRAGGALHLPAPQQDNSLEELSEFSKRNDDPPISIDLTFHLLRNMIEMARIENQREQAELNRKYLDEVGK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .** : :** :: * * . . * * ** . *.. .*: * :* .:*** . :. *.*:*.:**********.::*:** :.***:** ** :*.***", "identical_positions": 44, "similar_positions": 32, "identity": "31.43%" }, { "cls_id": "homologset.agr.MGI:1276124", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JU09-1", "uniprot_id": "A0A0G2JU09_RAT", "id": "A0A0G2JU09-1", "name": "E1A-binding protein p400", "aln": "MHHGSGPQNVQHQLQRSRSFTGSE-----------------------EEQPAHPNLPPSPAAPFAPSASPSAPQSPGYQIQQLMSRSPVAGQNVNITLQNVGPVVGGNQQITLAPLPLPNPTSPGFQFGAQQRRFEHGSPSYIQVTSPLSQQVQTQSPTQPNPGPGQTLQNVRAGAPGPGLGICSSSPTGGFVDASVLVRQISLS-PSSGGHFVFQEAPGLTQMAQGAQVQLQHSGAPITVRERRLSQPHAQSGG-TIHHLGPQSPATAGGTGLQPLASPNHITTASLPPQISSIIQGQLIQQQQQVLQGQPMNRSLGFERTPG-VLLPGVGGPSAFGMTSPPPPTSPSRTTMPPGLSSVPLTSMGSSGIKKVPKKLEEIPPASQEMAQMRKQCLDYHYKEMEALKEVFKEYLIELFFLQHLQGNMMDFLAFKKKHYAPLQAYLRQNDLDIEEEEEEEEEEEEKSEVINDEVKVVTGKDGQTGTPVAIATQLPPNVSAAFSSQQQPFQHQALTGSLVVGPGSTTEADPFKRQQVMPPT---EQSKRPRLEVGHPGVVFQHPGVN----AGVPLQQLMPTVQGGMPPTPQATQLT--GQKQSQQQYDPSTGPPVQNAASLHTPPPQLPARLPPASVPATALPSTLQFSQQSQMVEAPTQLQIPVKTQQLNAPIPAPLPSQLPAPSSQPAQPALHVSMPGKAQMQTSQLSSQTQTVASTRPPLESAQPCQRSLPTSSSSSSLVPVSGSGPG--PSPARSSPVNRPSSATNKALSPVTS-RSPGVAVSAPPKPQSPAQN--AASSQDGSQDKLAEQITLENQIHQRIADLRKEGLWSLRRLPKLQEAPRPKSHWDYLLEEMQWMATDFAQERRWKLAAAKKLVRTVARHHEEKKLREERGKKEEQSRLRRIAATTAREIEYFWSNIEQVVEIKLQVELEEKRKKALNLQKVSRRGKESRLKGFDTSPEHSMDLGISGRKRKASTSLTDDEVEDEEETIEEEEAHEGLVDHHTELSNLAKEAELPLIDLMKLYEGAFLPNFQWPQPEPDHEESSGEEDAEDCPSDRESRRDSVLIDSLFIMDQFKAAERMSIGKSN--TKDITEVTAVAEAILPKGSARVTTAVKFSAPSLLYGALRDYQKIGLDWLAKLYRKNLNGILADEAGLGKTVQIIAFFAHLACNEGNWGPHLVVMRSCNILKWELELKRWCPGLKTLSYVGTHRELKAKRQEWTEPNNFHICITSYKQFFRGYTAFSRVHWKCLVVDEMQRVKGMTERHWEAIFKLQSQQRLLLIDVPLHNTFLELWTMVHFLIPGIS------RPYLSFPLKAPNEENQDYYHKMVIRLHRVTQPFILRRTKRDVEKQLTRKYEHVLKCRLSSRQKALYEDVILQPRTQEALKSGHFVSVLSVLTRLQRICNHPGLVEPRVPGSSYAAGSLQYKSASLILRVLEREFWKETDLSMFDLIGL--ENKISRHEAELLY-KKKVTRKLMEEVFTSPPPSARPAAVKLKASRLFQPVQYGQKPEGRTVAFPS--THPPRMANTNASTATPQGQVRGRPPIATFSANPDTKAAAAPFQNSQASVGTPRHQPTSTSSTAAGPAHPSKLRAQTAVQASTPGPPLPPPQAPSLVAGQSAPPQRLVLTSQAQARLPSGEVVKIAQLASIAGPQSRVAQPETPVTLQFQGNKFTLSHSQLRQLTAGQPLQLQG---SVLQIVSAPGQPYLRAPG-PVVMQTVSQAGAVHSTLGSKPPTSGPSPAPLSTQVGVPGRVAVSAMAVGEPGLASKPASPAAGPTQEEKSRLLKER-------LDQIHFINERRCSQAPVYGRDLLRICSLPGRRKRPLCWSLDSN------LGKGPKGADYDTSLSKSEGDLILTLSQRQESLQDVLDRVACVIPPVVATPPSLWVERPPSLYSSRLRALRQCLREHTGPYHRQLQQLTALRSLQFPELRLVQFDSGKLEALAILLQKLKSEGRRVLILSQMVLMLDILEMFLNFHYLTYVRIDENANSEQRQELMRSFNRDRRIFCALLSTHSRATGINLVEADTVVFYDNDLNPVMDAKAQEWCDRIGRCKDIHIYRLVSGNSIEEKLLKNG-TKDLIREVAAQGNDYSMAFLTQRTIQELFEVYSPMDDAGFPVK------AEEFVVLSQEPSVSETIAPKIARPFIEALKSI----ECLEEDAQRSTEEAVPGSSTVA--------VSSDSDGSRYDEEPSQLEELADFMEQLTPIEKYALNYLELFHTTTEQEKERSSEDLVMATMKDWETRNARALQEREAQLQLEQEEAELLTYTREDAYSMEYVYEDADGQTEVMPLWTPPTPPQD-DNDIYIDSVMCLMYETTPIPEAKLPPVYVRKERKRHKTDPSAAG--RKKKQRHGEAVVPPRSLFDRATPGMLKIRREGKEQKKNLLLKQQTPFAKPLPTYVKSSGEPAQDSPDWLIGEDWALLQAVKQLLELPLNLTIVSPAHTPNWDLVSDVVNSCSRIYRSSKQCRNRYENVIIPREEG--------------------KSKNNRPLRTSQIYAQDENATHTQLYTSHFELMKMTAGKRSPPIKPLLGMNPFQKNPKHASVLAESGIN-YDKPLPPIQVASLRAERIAKEKK-------------ALADQQKAQQPPVTQPPPQQQPQQQQPPQQQQQ--QPPPPPQQPPPPVPQPQAASSQTPAGQPVVQP--QVQAQPQPPPVQAQSKGQATMTTVGSAAVLAGTIKTSVTGTSIP-------------TGTVSGNVIVNTIAGVP-ATFQSINKRLASPVAPG---------ALTTSGGSAPAQVVHTQQ--------RAVGSPATATTDLVSMTTTQGVRAVTSVTASAVVTTNLTPVQT--PTRSLVTQVSQATGVQLPGKTITPAAHFQLLRQ----------------QQQQQQQQQQQQQQQQ---------------TSQVQVPQLQGQAQSPAQMKAVGKLAPEHIIKMQKQKMQLPPQPPPPQAQPGPPQQPAQVQVQ------TAQPPQQQQSPQLTTVTAP-RPGALLTGTTVANLQVARLTRVPTSQLQAQGQMQTQ--------------------------------------------------TPQPAQVALAKPPV------VSVPAAVVSSPGVTTLPMNVAGISVAIGQPQKTAGQTVVA----------QPVHVQQLLKLKQQ-AVQQQKAIQP--QVAQGQAAVQQKLTTQQITTQGPQQKVAYAAQPALKTQFLTTPISQAQK--------------LAGTQQVQTQIQVAKLPQVVQQQTPVASIQQVASASQQASPQTVTLTQATAAGQQVQMIPTVTATAQVVQQKLIQQQVVTTASAS-LQTPGGPSPAQ-----LPTSSDSPNQQPKLQMRVP----------AVRLKTPTKPPCQ--------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CHI8-1", "uniprot_id": "EP400_MOUSE", "id": "Q8CHI8-1", "name": "E1A-binding protein p400", "aln": "MHHGSGPQNVQHQLQRSRSFTGSE-----------------------EEQPAHPNLPPSPAAPFAPSASPSAPQSPGYQIQQLMSRSPVAGQNVNITLQNVGPVVGGNQQITLAPLPLPNPTSPGFQFGAQQRRFEHGSPSYIQVTSPMSQQVQTQSPTQPSPGPGQTLQNVRAGAPGPGLGICSNSPTGGFVDASVLVRQISLS-PSSGGHFVFQEAPGLTQMAQGAQVQLQHSGAPITVRERRLSQPHAQSGG-TIHHLGPQSPAAAGGTGLQPLASPNHITTASLPPQISSIIQGQLIQQQQQVLQGQPMNRSLGFERTPG-VLLPGVGGPSAFGMTSPPPPTSPSRTTMPPGLSSVPLTSMGSSGMKKVPKKLEEIPPASQEMAQMRKQCLDYHYKEMEALKEVFKEYLIELFFLQHLQGNMMDFLAFKKKHYAPLQAYLRQNDLDIEEEEEEEEEEEGKSEVINDEVKVVTGKDGQTGTPVAIATQLPPNVSAAFSSQQQPFQHQSLTGSLVVGPGSATEADPFKRQQVMPPT---EQSKRPRLEVGHPGVVFQHPGVN----AGVPLQQLMPTVQGGMPPTPQATQLT--GQKQSQQQYDPSTGPPVQNAASLHTPPPQLPARLPPASVPATALPSTLQFSQQSQMVEASTQLQIPVKTQQLNAPIPAPLPSQLPAPSSQPAQPALHVPMPGKAQMQTSQLSSQTQTVASTRPPLDSAQPCQRSLPTSSSSSSLVPVSGSGPG--PSPARSSPVNRPSSATNKALSPITS-RSPGVAVSAPPKPQSPAQN--AASSQDGSQDKLAEQITLENQIHQRIADLRKEGLWSLRRLPKLQEAPRPKSHWDYLLEEMQWMATDFAQERRWKLAAAKKLVRTVARHHEEKKLREERGKKEEQSRLRRIAATTAREIEYFWSNIEQVVEIKLQVELEEKRKKALNLQKVSRRGKESRLKGFDTSPEHSLDLGISGRKRKASTSLTDDEVEDEEETIEEEEAHEGLVDHHTELTNLAKEAELPLIDLMKLYEGAFLPNFQWPQPEPDHEESSGEEDVEDCPSDRESRRDSVLIDSLFIMDQFKAAERMSIGKSN--TKDITEVTAVAEAILPKGSARVTTAVKFSAPSLLYGALRDYQKIGLDWLAKLYRKNLNGILADEAGLGKTVQIIAFFAHLACNEGNWGPHLVVMRSCNILKWELELKRWCPGLKTLSYVGSHRELKAKRQEWTEPNNFHICITSYKQFFRGYTAFSRVHWKCLVVDEMQRVKGMTERHWEAIFKLQSQQRLLLIDVPLHNTFLELWTMVHFLIPGIS------RPYLSFPLKAPNEENQDYYHKMVIRLHRVTQPFILRRTKRDVEKQLTRKYEHVLKCRLSSRQKALYEDVILQPRTQEALKSGHFVSVLSVLTRLQRICNHPGLVEPRVPGSSFAAGSLQYKSASLILRVLEREFWKETDLSIFDLIGL--ENKITRHEAELLC-KKKVTRKLMEEVFASPPPSARPAAVKLKASRLFQPVQYGQKPEGRTVAFPS--THPPRMANTNTSTATPQGQVRGRPPIATFSANPDTKG---------------------------------------------------------------------------------GEVVKIAQLASIAGPQSRVAQPETPVTLQFQGNKFTLSHSQLRQLTAGQPLQLQG---SVLQIVSAPGQPYLRAPG-PVVMQTVSQAGAVHSTLGSKPPTSGPSPAPLTPQVGVPGRVAVSAMAVGEPGLASKPASPAAGPTQEEKSRLLKER-------LDQIHFINERRCSQAPVYGRDLLRICSLPGRRKRPLCWSLDSN------FGKGPKGVNYDMSLSKSEGDLILTLSQ--ESLQDVLGRVACVIPPVVATPPSLWVARPPSLYSSRLRALRQCLREHTGPYHRQLQQLTALRSLQFPELRLVQFDSGKLEALAILLQKLKSEGRRVLILSQMVLMLDILEMFLNFHYLTYVRIDENANSEQRQELMRSFNRDRRIFCALLSTHSRATGINLVEADTVVFYDNDLNPVMDAKAQEWCDRIGRCKDIHIYRLVSGNSIEEKLLKNG-TKDLIREVAAQGNDYSMAFLTQRTIQELFEVYSPMDDTGFPVK------AEEFVVLSQEPSVSETIAPKIARPFIEALKSI----ECLEEDAQRSTEEAVPGSSSVA--------VSSDSDGSRYDEEPSQLEELADFMEQLTPIEKYALNYLELFHTTTEQEKERISEDLVMASMKDWETRNARALQEREARLQLEQEEAELLTYTREDAYTMEYVYEDADGQTEVMPLWTPPTPPQD-DNDIYIDSVMCLMYETTPIPEAKLPPVYVRKERKRHKTDPSAAG--RKKKQRHGEAVVPPRSLFDRATPGMLKIRREGKEQKKNLLLKQQTPFAKPLPTYVKSSGEPAQDSPDWLIGEDWALLQAVKQLLELPLNLTIVSPAHTPNWDLVSDVVNSCSRIYRSSKQCRNRYENVIIPREEG--------------------KSKNNRPLRTSQIYAQDENATHTQLYTSHFELMKMTAGKRSPPIKPLLGMNPFQKNPKHASVLAESGIN-YDKPLPPIQVASLRAERIAKEKK-------------ALADQQKAQQPPVTQPPPQQQQQQQQQQQQQQQQQQPPPPPQQPPPPVPQPQAASSQTPAGQPAVQPQPQPQVQTQPQPVQPQSKGQPTMTTVGSAAVLAGTIKTSVTGTSIP-------------TGTVSGNVIVNTIAGVPAATFQSINKRLASPVAPG---------TLTTSGGSAPAQVVHTQQ--------RAVGSPATATTDLVSMTTTQGVRAVTSVTASAVVTTNLTPVQT--PTRSLVTQVSQATGVQLPGKTITPAAHFQLLRQ----------------QQQQQQQQQQQQQ------------------TSQVQVPQLQSQAQSPAQIKAVSKLGPEHIIKMQKQKMQLPPQPPPPQAQPGPPQQPAQVQVQ------TPQPPQQQQSPQLTTVTAP-RPGALLTGTTVTNLQVARLTRVPTSQLQAQGQMQTQ--------------------------------------------------TPQPAQVALAKPPV------VSVPAAVVSSPGVTTLPMNVAGISVAIGQPQKTAGQTVVA----------QPVNVQQLLKYKQQTAVQQQKAIQP--QVAQGQAAVQQKLTTQQITTQGPQQKVAYAAQPALKTQFLTTPISQAQK--------------LAGTQQVQTQIQVAKLPQVVQQQTPVASIQQVASASQQASPQTVTLTQATAAGQQVQMIPTVTATAQLVQQKLIQQQVVTTASAS-LQTPGGPSPAQ-----LPASSDSPSQQPKLQMRVP----------AVRLKTPTKPPCQ--------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96L91-1", "uniprot_id": "EP400_HUMAN", "id": "Q96L91-1", "name": "E1A-binding protein p400", "aln": "MHHGTGPQNVQHQLQRSRACPGSEG----------------------EEQPAHPNPPPSPAAPFAPSASPSAPQSPSYQIQQLMNRSPATGQNVNITLQSVGPVVGGNQQITLAPLPLPSPTSPGFQFSAQPRRFEHGSPSYIQVTSPLSQQVQTQSPTQPSPGPGQALQNVRAGAPGPGLGLCSSSPTGGFVDASVLVRQISLS-PSSGGHFVFQDGSGLTQIAQGAQVQLQHPGTPITVRERRPSQPHTQSGG-TIHHLGPQSPAAAGGAGLQPLASPSHITTANLPPQISSIIQGQLVQQQQ-VLQGPPLPRPLGFERTPG-VLLPGAGGAAGFGMTSPPPPTSPSRTAVPPGLSSLPLTSVGNTGMKKVPKKLEEIPPASPEMAQMRKQCLDYHYQEMQALKEVFKEYLIELFFLQHFQGNMMDFLAFKKKHYAPLQAYLRQNDLDIEEEEEEEEEEEEKSEVINDEVKVVTGKDGQTGTPVAIATQLPPKVSAAFSSQQQPFQ-QALAGSLVAGAGSTVETDLFKRQQAMPSTGMAEQSKRPRLEVGHQGVVFQHPGAD----AGVPLQQLMPTAQGGMPPTPQAAQLA--GQRQSQQQYDPSTGPPVQNAASLHTPLPQLPGRLPPAGVPTAALSSALQFAQQPQVVEAQTQLQIPVKTQQPNVPIPAPPSSQLPIPPSQPAQLALHVPTPGKVQVQASQLSSLPQMVASTRLPVDPAPPCPRPLPTSSTSS-LAPVSGSGPG--PSPARSSPVNRPSSATNKALSPVTS-RTPGVVASAPTKPQSPAQN--ATSSQDSSQDTLTEQITLENQVHQRIAELRKAGLWSQRRLPKLQEAPRPKSHWDYLLEEMQWMATDFAQERRWKVAAAKKLVRTVVRHHEEKQLREERGKKEEQSRLRRIAASTAREIECFWSNIEQVVEIKLRVELEEKRKKALNLQKVSRRGKELRPKGFDALQESSLDSGMSGRKRKASISLTDDEVDDEEETIEEEEANEGVVDHQTELSNLAKEAELPLLDLMKLYEGAFLPSSQWPRPKPDGEDTSGEEDADDCPGDRESRKDLVLIDSLFIMDQFKAAERMNIGKPN--AKDIADVTAVAEAILPKGSARVTTSVKFNAPSLLYGALRDYQKIGLDWLAKLYRKNLNGILADEAGLGKTVQIIAFFAHLACNEGNWGPHLVVVRSCNILKWELELKRWCPGLKILSYIGSHRELKAKRQEWAEPNSFHVCITSYTQFFRGLTAFTRVRWKCLVIDEMQRVKGMTERHWEAVFTLQSQQRLLLIDSPLHNTFLELWTMVHFLVPGIS------RPYLSSPLRAPSEESQDYYHKVVIRLHRVTQPFILRRTKRDVEKQLTKKYEHVLKCRLSNRQKALYEDVILQPGTQEALKSGHFVNVLSILVRLQRICNHPGLVEPRHPGSSYVAGPLEYPSASLILKALERDFWKEADLSMFDLIGL--ENKITRHEAELLS-KKKIPRKLMEEISTSAAPAARPAAAKLKASRLFQPVQYGQKPEGRTVAFPS--THPPRTAAPTTASAAPQGPLRGRPPIATFSANPEAKAAAAPFQTSQASASAPRHQPASASSTAASPAHPAKLRAQTTAQASTPGQPPPQPQAPSHAAGQSALPQRLVLPSQAQARLPSGEVVKIAQLASITGPQSRVAQPETPVTLQFQGSKFTLSHSQLRQLTAGQPLQLQG---SVLQIVSAPGQPYLRAPG-PVVMQTVSQAGAVHGALGSKPPAGGPSPAPLTPQVGVPGRVAVNALAVGEPGTASKPASPIGGPTQEEKTRLLKER-------LDQIYLVNERRCSQAPVYGRDLLRICALPSHGRVQWRGSLDGR------RGKEAGPAHSYTSSSESPSELMLTLCRCGESLQDVIDRVAFVIPPVVAAPPSLRVPRPPPLYSHRMRILRQGLREHAAPYFQQLRQTTAPRLLQFPELRLVQFDSGKLEALAILLQKLKSEGRRVLILSQMILMLDILEMFLNFHYLTYVRIDENASSEQRQELMRSFNRDRRIFCAILSTHSRTTGINLVEADTVVFYDNDLNPVMDAKAQEWCDRIGRCKDIHIYRLVSGNSIEEKLLKNG-TKDLIREVAAQGNDYSMAFLTQRTIQELFEVYSPMDDAGFPVK------AEEFVVLSQEPSVTETIAPKIARPFIEALKSI----EYLEEDAQKSAQEGVLGPHTDA--------LSSDSENMPCDEEPSQLEELADFMEQLTPIEKYALNYLELFHTSIEQEKERNSEDAVMTAVRAWEFWNLKTLQEREARLRLEQEEAELLTYTREDAYSMEYVYEDVDGQTEVMPLWTPPTPPQD-DSDIYLDSVMCLMYEATPIPEAKLPPVYVRKERKRHKTDPSAAG--RKKKQRHGEAVVPPRSLFDRATPGLLKIRREGKEQKKNILLKQQVPFAKPLPTFAKPTAEPGQDNPEWLISEDWALLQAVKQLLELPLNLTIVSPAHTPNWDLVSDVVNSCSRIYRSSKQCRNRYENVIIPREEG--------------------KSKNNRPLRTSQIYAQDENATHTQLYTSHFDLMKMTAGKRSPPIKPLLGMNPFQKNPKHASVLAESGIN-YDKPLPPIQVASLRAERIAKEKK-------------ALADQQKAQQPAVAQPPPPQP--------------QPPPPPQQPPPPLPQPQAAGSQPPAGPPAVQPQPQPQPQTQPQPVQAPAKAQPAITTGGSAAVLAGTIKTSVTGTSMP-------------TGAVSGNVIVNTIAGVPAATFQSINKRLASPVAPG---------ALTTPGGSAPAQVVHTQPP------PRAVGSPATATPDLVSMATTQGVRAVTSVTASAVVTTNLTPVQT--PARSLVPQVSQATGVQLPGKTITP-AHFQLLRQ----------------QQQQQQQQQQQQQQQQQQQQQQQQQQQQTTTTSQVQVPQIQGQAQSPAQIKAVGKLTPEHLIKMQKQKLQMPPQPPPPQAQSAPPQPTAQVQVQ------TSQPPQQQ-SPQLTTVTAP-RPGALLTGTTVANLQVARLTRVPTSQLQAQGQMQTQ--------------------------------------------------APQPAQVALAKPPV------VSVPAAVVSSPGVTTLPMNVAGISVAIGQPQKAAGQTVVA----------QPVHMQQLLKLKQQ-AVQQQKAIQP--QAAQGPAAVQQKITAQQITTPGAQQKVAYAAQPALKTQFLTTPISQAQK--------------LAGAQQVQTQIQVAKLPQVVQQQTPVASIQQVASASQQASPQTVALTQATAAGQQVQMIPAVTATAQVVQQKLIQQQVVTTASAP-LQTPGAPNPAQ-----VPASSDSPSQQPKLQMRVP----------AVRLKTPTKPPCQ--------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AVF1-1", "uniprot_id": "A0A8M3AVF1_DANRE", "id": "A0A8M3AVF1-1", "name": "", "aln": "MHHGGGPPNVQRNLQRSKSFTGSEAEDQQQQQSQQPQQQQQQPVPVTQQQSANANLPQSPVTSFAPSASPSAPQSPNYQI--IMSRSPVTGQNMNITLQNVGPMVTGNQQITLTSLPLQSPASPGFQHQPQQWRFEPGSSSYIQVTSPLPQTMQPQSPTQHSPVPLQAVP--RPNAPGSALGVCGQSPTR-FVEANIMVRQINLSSPPGSGHFVYQDGAGLATG----TVHLTSPGTPGAVRERRLSQPHSQPGSSTVHHKALPSQVPT-------LGSPGPITTTNLPPQISSIIQGQLA-------------RPTMFEKTSQSVVGVANSAAATFGVPSTIPPSSPSRSNSSQGLSSQSLTPTSMKKMQ--PKKLEEIAPSNPEVAQLRKQCLEHHGKKMEGLKEVFKEYLIELFFLQHLQGNMMDYIAFKKKPCVPLFTYLRQNDLDLEDEEEEEEQ----SEVINDEVKVVTGKDGQTVTPVAIATQLPPNVSAAFSTQQQFQTHAGVASGSISNP---VDMEAFKRQQAMAQA---DQAKRSRMEVGRHGMIFQHPAVTPLGSPGVPLQQLMPTAQGGMPPTPQTVQIG--GQKQNQQQYDPSKGPPVQNAASLHTPPPQLPGRLPQAGLPLSLAQGQAMVVDQQATVTGG---QLQVKVQGAGAVLAPVNPHAQLQAQLQQMQSGLHLQMQQQQQMQQSVMQPGQATVTLLRPGAETSQAAQRLMSNSLSSPVISSVPLTSPSSLPSPLTSAPVRTPN--TGPSLSPVAQSKLTATNGTVGLKLSSLGQSSIGQNSQESSQDKQAEQAKLESHVHQRIAELRKEGQWSASRLPKLQESCRPKSQWDYLLEEMQWMAADFAQERRWKMAAAKKLVRTCARYHVEKKKMGEREKKEEEMRLRHIASTIARGVDYFWSNIEQIVEIKHHFEIYDKQKKVLCLQKASSKGQCAK-SGQSSDKESKRETGPS-RKRKSSTSLSDVEVEDEESTIEEQEATEAAADQKAELAELTKEAEVPLDDLVKQYAGAYAEGFEWPQPSSQSEDEDREE-AEDMNTPLDSPHDAVLIDSLLSMDQYRGAERTTSGPDGKPTKDIAEVAAATDLILPKGSARTTLTSRSSPPSLLHGSLREYQQVGVEWLASLHRKNLNGILADETGLGKTVQTVAYFAHLACNQGIWGPHLVVVRTCKLLNWEMEFKRWCPGLKILLYLGSRRQRRYKRSRWCEPNNFHVCVTSYKLLLKDQSHFLRRRWKHLVLDEVQLIKNMTEKHWETIFNIKSQQRILLINTPLQNTLKELWTMIHFLLPGIT------HPYLNFPIKPGTDQNQDYCHKLVIRLHRMIQPFILRRSKRDVEKQMPKKYEHILKCRLSKRQKSMYEDILIQPSAQEALKTGHFVRVLEVLMQLQKICNHPDLIQPRDTHNSYVCQPLQYNTPSLLLNALQQDQWKTVDLSLFDLINN--EGKLTRYEAEEALPKIRMTKQLIEEIYNARDPPARPRPCKIKPMRLFLPVQYGTKPEGRLVPMTSSTTQAPRTTTVTTAPTTTTNSVTAVSNTQPRGKSPLTTTPSAQASIINCSSGP---LLTGAIPNPPSIPLSMGVPGVTTMPAVTPQAPSPVPLQPSLVS------QRLVLSSQAQARLPSGDVVKVAQLVG----QSRIAQPETPVTLQFQGNKFTLSQSQLRQLTTGQPLQLQGTLGNILQIVSAPGQPLLRPQGPPMVMPTVPQAVPAQNSSGTPPPATSTP-----PQANTMASTTVTPANTDMETNAKHSNNSTSQESSEERNRQLKER-------LSSLFHANERRSSRSVLYGSDLVKTCSVYEGRPPPAFPAPQHSRWSWVGRDSCIRAQQTCVSTVASLRSAILSNTEQEAAASTLLKRFSWILPAAVAPPPQLYACNPPPSYSLAQKSFRRQLQEASAPFNAEIRKLACPPVASFPDAHMLEMDSGKLEALSILLQKLSAENRRVLIFTQMASMLDILESFLDHRHLTYVRLDESLSLEERQEQVKKYNRNRQIFCTILTNRCCSAMGHVFDADTIVFYDTDLNPSMDMRTQEWCDKIGRSKDIHIYRLESGNSIEEKLLKNG-TKDLIREVAAQGMDYTLAFLTQRTIQDLFEV-----EAGSGEK------VEEFVVLHQEPSPSESIPPHVARPYIQALNTIRQETQYEEEEGQVEVDEDVKSDKEKAGG-----PVEMDIEEG-AREETSQLEELAAVMEQLTPIERYALHYLEYLHIS---EDEQVVKERMETTKRGWELQLQQKLKVEKEEQMIQEDEEDLLSYTREDAYNMEYVFENEDGQTEIMPLWTPPTPPQD-DNDIYIDSVICLMYDTAPMPESKLPPVYVRKERKRH-MDPSALG--RKKKKGHGESVIPPRSLFDKAS--LLKVRRDVKDQKKNFSLKQQAPFAKPLPSLLKPAMESGQDNPEWLISEDWALLQAVKQLLELPLNLTIVSPAHTPNWDLVSDVVNSCSRIYRSPKQCRYRYENVIIPREEGKLIYDANPKK---NKTKSIYKSKNSRPLRTCQIYTQDDNATQIQLYSNRFELMKIIASKRSPPIKPLLGMNPFQKNPKHASVLAESGIS-YDKPLPPIQVASQRAERIAKEKKQ------------ALAEQQRAQQLAQQQ--------------------QQTTGAAQPQGAAAQPQAQTQTPAAG---------AQANAVPQPSQ------PGAAAVANTAVLTGALKTAAAGTSIQPA-----------AGTVSGNVIVNTVAGVPPGQFQAN-KRLASPVIPG---------ALPATG-TATAQVVHTRG----------AVPAAAAPAEVVAIATSQSVRAVTPVTASAVVSTNLTSGQS--QTR---TLVATAPAVQLS--QNKQITQQLLFRQ----------------QQLQQQQQQQQQQ---------------------------QPQATSP-QIKAVGKPQ-QELLKQKKLQMAQQQVAAAVAAAQGQQAPSTQQPQQ------VHATPAATANPQIATVAAP-RAGAVLAGTTVTNLQVARLTRVP-----APGSIQAQ--------------------------------------------------PGQPAQVTLTKPPP------VVSVPAVVSS-GVTTLPVTMAGISVAIGQAPKTGGPMVTHP--------FQVQQVQQLLHRQKQQAVAQAAAVQKAAQPQQTQAAVQQKAAQTPAQQQ-QKVYTTAPLQPGIKTQFFTTSITQPQK--------------TAASP----QIQVTKIPQIVQQQIVSSPQQIQAQPQTVALTQAAPAAGSVQAQAQVQVIPAG--TAQVVQQKLLQQQVVTAAASPQIQTPPPHSPAQQQSTAAPPASETPAQQTTATPQPPQAKGNTRTGAAMRSKTPAKPSGGS-------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9NDJ2-1", "uniprot_id": "DOM_DROME", "id": "Q9NDJ2-1", "name": "Chromatin remodeling protein domino", "aln": "MNEGNSAGGGHEGLSP------------------------------------------------APPAVPDRVTPHSTEISVAPANSTSTTVRAAGSVGAALPATRHHQHIATQVKGIASSSSK-----------------------QQKQLASAQLPVPLSPLPQQQQQTAEATAAAAAPAHSNVSVSSSTIEASVLPPQAKRQRLDDNEDRTSAASIVGPAESS---------------------------------------------------------------------------------------------------------------NIVSSLLPASVASSSEVGGLSSTALQDLNALKKRILQQKLQILRNLKERHLENVSEYFYLQNGGSMMDYPAWRKKTPTPQFISYSNANRIDQLIHEDKPSTSAAAAAAQN-QKYTTQQTDSVESSLVSGIGTGATKGAPLDGNISNSTVKTNTQSQVPSKIGSFTESTPAATESNSSTTVPGTATSGAATSTSATSAEASG----NVLAVEAEIKIPAVGATPVAIS----TKLPAAVVQLTQQGGTPLLPCNTSAGSTALRRPQGQNNASSGSAAASGGGGSLTPTPLYTGNGPAALGGSGGLTPGTPTSGSLLSPALGGGSGTPNSAAQEFSFKAKQEVYVMQRISELQREGLWTERRLPKLQEPSRPKAHWDYLLEEMVWLAADFAQERKWKKNAAKKCAKMVQKYFQD------KATAAQRAEKAQELQLKRVAS-FIAREVKSFWSNVEKLVEYKHQTKIEEKRKQALDQHLSFIVDQTEKFSQQLVEG-------MNKSVADTPSLNSSRLTSPKRESDDDFRPE-------------SGSEDDEETIAKAEEDAADVKEEVTALAKESEMDFDDFLNDLPPGYLENRDKLMKEEQSSAIKTETPDDSDDSEFEAKEASDDDENTISKQEEAEQEIDHKKEIDELEADNDLSVEQLLAKYKSEQPPSPKRRKLAPRDPELDSDDDSTAVDSTEESEDAATEDEEDLSTVKTDTDMEEQDEQEDGLKSLMADADATSGAAGSGSTAGASGNKDDMLNDAAALAESLQPKGNTLSSTNVVTPVPFLLKHSLREYQHIGLDWLVTMNERKLNGILADEMGLGKTIQTIALLAHLACAKGNWGPHLIVVPSSVMLNWEMEFKKWCPGFKILTYYGSQKERKLKRVGWTKPNAFHVCITSYKLVVQDQQSFRRKKWKYLILDEAQNIKNFKSQRWQLLLNFSTERRLLLTGTPLQNDLMELWSLMHFLMPYVFSSHREFKEWFSNPMTGMIEGNMEYNETLITRLHKVIRPFLLRRLKKEVEKQMPKKYEHVITCRLSNRQRYLYEDFMSRAKTRETLQTGNLLSVINVLMQLRKVCNHPNMFEARPTISPFQMDGITFHTPRLVCDIMEYDPFTQINLETLNLLLLHLEQTMTAYVSHKSR-LLAPPRKLIEDIDTAPLPAPRCPNGKYRFHIRVRSAELAQRIKLNAVKVGA--SPAMRLEGSKIMPMRNLLPSGRVLKRVSASINPVNMALKP---------------------------------------------------------------------------------VVINSVVTTTSSSTTASSPTGALSVLSN-SKLLGARSQINAPTPAKVAKTMQDGKPFFYLTPATNSGAAGARLTLTSKTTASASTTTSRTTVTASTTSGQQLIRDPIVKDLATHVKSTVQKQSIANGKTEPEEETEAEDPYKVQELIQMRKEQRLAALKRMAMINRRRTDATPIYGEDCREAIQRCMQATRSLKRSTWQT------RGYANCCTAMAHRNGWSLNHLLKSFEERCADLKPVFANFVIYVPSVCAPRIRRYVQNLSSTHWQHEQRIENIVDQALRPKLALLHPIISEMTTKFPDPRLIQYDCGKLQTMDRLLRQLKVNGHRVLIFTQMTKMLDVLEAFLNYHGHIYLRLDGSTRVEQRQILMERFNGDKRIFCFILSTRSGGVGINLTGADTVIFYDSDWNPTMDAQAQDRCHRIGQTRDVHIYRLVSERTIEVNILKKANQKRMLSDMAIEGGNFTTTYFKSSTIKDLFTMEQSEQDESSQEKSENKDRIVATTTLSDTPSTVVETEKQSLRAFEHALAAAE---DEQDVQATKTAKAEVAADLAEFDENIPIATEDPNAEGGPQVELSKADLEMQNLVKQLSPIERYAMRFVEETGAAWTAEQLRAAEAELEAQKREWEANRLAAMHKEEELLKQETEAEEMLTYSRKDSSNQVWISRN---TMEQMPMWCPPTPPQDNDNDIYIDYSLSFMYELEPIAETDLPPVYVRKEHKRSRTDAGYDGSRRPNKMRREDNYVPPRSLFDRPTPQLARLRRELKSQRFRGSFKPNMPIPGLKPQLPTKPLTEPEAMAEWCVFEDMAILHVLVNLQGLPCSLMLLSPGQTPNWDLVSEMVNFCSKTYRSARQCRWRYETHIQPREEGKVVESPKKQKKLKPTLRTEYLKSPLRYLRTTQLYVSDNNASFYKTMRSRFDSIKTAYLKKAPPPKRQFSAPSLMN-PKHMEVLQEFGILNYDQPVSPQNIAAMKANKIREKQRGQQMSQPPVGVGVVQQMQQQSQQQQQPAPPPLPQQQQPQQVVQQVQQQQQQQQQQQQQQVVQQQLPTVSNVQQTLPVQQTVELVQQQPTTTTTVAVPAAGGQLQQLQIQHLTSSNVSPGQQTAILLHQPQQQLRTHPGQGGQSNTQQLVKTIVGTSSSLTAGQLQQLAQQSAVASGGQSSVSVVLTTPVQTLPSVVQPQIGSGAQIVSISSQTLPVNSSPQLGSIVQTQSLPQVVSVSTLPTVGTVLTTTANQPQQQHQTTAVTTLNTTMLRGQRIVSTAAGNTLQQRTTAGGQSIVSMPNLGQGASPSQFQTQLRLAAVPTSPATQTTQLVTTKGIPVSALQQGGKTTVIPVTQQSGGAHIQLYRQRSLKVLQTTTQAVPSGSAGATGATANLVQAGGTIIQASNMATHVTSQKVAVSGMPGTSTTVQAGNVVSSVQMHGQARTQFIKQMAAGKQQLQRQVVSADGTTTTTAAGDMLLVKRHNILAAQKAQQASGALFTTTTGQQQQQQQQQGQLPVAGQPQQVTQHQIASLVKASTAAAASGSSVNAGGVTVSATNPTVQAGSVNMTLPQLKPGSQIKVTMPNQMRHLQMQQQLTMPRKISRMTQLVSASGQPTATNIITTTGPQQQQQGVTVSGGGTLPTVASQQQQQQHQQKVGGGNSVQAQLLHIQNTKGLSNSVTMQQIQQVMRSGQQGTLATTNLVLGKTSVGRVIPVSVASQANQRQTIQVVSAASAQALAAGNLRTHVAGPSIASTLKVAAPGSAGGQTTQQTLIAALQHNQRQNASPVRLQTTAGGNLLAVVQQQQQQQHTSIAGPTAGPAEVMTITQTTTTLPTVGSLQQQQQQQQQQGGISQPTTQQVRKLVQKKILIRSEKE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:.* .. . :. *. **.* *. . . :* .*. : . :: . * . :*:*: : ..:* * ..* *. .* * * .. *.... . .. * : ::*.:: * . . .. . . . . .: *. *:* : : **** .* . : :**: : . . : .: : : .::: *:.: :.* :* : .:.* .. : ** . :: :. : * : .. .* .. ... : :.* ** . . ::. . :. : .. . .. . : . *: .: . . :* : * *** * * .. . :: * * :.*.*... .... . . * *.: : . . . : : . : : .* : * .. : . . * .. :. * . ::... .. *. ::. . : : .. : . :: :: :: .: . ::::: * : . : *. : . * . : ** * : . . *. *. : : .: :* .: * .:: : : :::...: :. . .. : : . . ::: . . *:: ::. *: : :: .. . .. * * . .. . . : *: . : * :. . : : . ... . * . . : :.:* :: : ***.: : * ** :**:**::*::**..: .::******** *****:* :* :***** :* *****:*: :. :*:**:*:*:****:* * * *:::: : ** * :** **:*:***. ..:. * * :** *::** * :*.:..::*: ::.:.:::*:** . **:* : ***:::***:* : : ::. *: : . :* ..:: ***:: :**:*** *::****:.:****::.****.**: :***.: :. ::*:*::*::: *:.:* :*:::****.:.:.* . ..: : : :. *: :: : :. :*. ::*: * .:: : :. .::*:*:: : *..* * : . ..: . : : . * . : : . * . . . . .* * : .:. .: :.* .::: : .*: ::**:. *..: : .: :..*... . *.. : .. : : ..: . . . . . ... . : . :: * *. : *.** . : :** * . : . * : : . . :: .. :*.. *. . . .. : : :.. : : * :: . .**: :::: *.***::: **::*. :.:****::** ***:** **:.: *:*:* . *:** :. :* :::*** :*:.:. . :: ***::***.* ** ** ::*: *.:**: :*:***** * .:** ::**:. * :: ::* :* ::: :::.. **::** : : . * ..* : ** : *.: .** : : : :. .. * . . : : * .. *: .::**:***:**:.::* : *. : : : : : ** :: .: : : ::*:*:*:*: . :: .: * **:* ******* *.***:* :.:**: *:.*:.*********:** *.. * * :* : : :*******:.: : ::**: *.*: . :* : *:. * . . : .:* : ** *:*:.: :* ** .* ::**.:********::** **: ***.:*** ***. * ***** .. * *** *:*..*:**: : .:*: :* *::** * :. .: : *** .** * ** **:*:.* ::*: :*::* :::: . **::** * * * . . * :. . . : :. :... : : * . : :*:*:.*.. . . ::**. . .*.:. : .: * .. :..:: ::. :*.: *..*:: ..* * **. . : . *: . * : ::* * . .* * * : * : :. . .: : :. :: . . . .:: . . . :::. * . :: :*..*:.:*: :*. * *. * * * .*:.:: * : . :: ..: .:. .*::*: :. .* : :*: : : * : :. * . . . : .: . : * * *: : .: : :: *:::. : : :. . : : * : : . :** : :: :*. .: :. ::.. ... :: *: . .:: : : . ", "identical_positions": 505, "similar_positions": 965, "identity": "14.37%" }, { "cls_id": "homologset.agr.MGI:1276125", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0RAP1-1", "uniprot_id": "M0RAP1_RAT", "id": "M0RAP1-1", "name": "", "aln": "MLLRPRRLPAFAP---PSPGSPDAELRAAGDVPVTTSDAFATSGAMADPGSPKAPVSPGSAQRTPWSARETELLLGTLLQPAVWRSLLLDRRQALPTYRRVSAALARQQVRRTPAQCRRRYKFLKDKLRDSQGQPSGPFDDQIRQLMGLLGDDGPPRVRRRSAGPGRPQRRGRSAFSALAPAPAVVEQEAELPLAAENAEPAPALRFSSSTTKSAGVRRITSSPPP---TAIDTLPPEPGHTLESSPTPTPDHDTENPNEPPGLSQGRAS-PQVAPQSLNTALLQTLTHLGDISTVLGPLRDQLSTLNQHVEHLRGSFDQTVSLAVGFILGSAASERGILGDLRQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6J1H4-1", "uniprot_id": "UTF1_MOUSE", "id": "Q6J1H4-1", "name": "Undifferentiated embryonic cell transcription factor 1", "aln": "MLLRPRRLPAFSP---PSPASPDAELRSAGDVPVTTSDAFATSGGMAEPGSPKAPVSPDSAQRTPWSARETELLLGTLLQPAMWRSLLLDRRQTLPTYRRVSAALARQQVRRTPAQCRRRYKFLKDKLRDSQGQPSGPFDNQIRQLMGLLGDDGPPRVRRRSTGPGRPQRRGRSSLSALAPAPAPVEQEAELPLAAENDEPAPALRFSSSTTKSAGAHRITSSPPL---TSTDTLPPEPGHTFESSPTPTPDHDVETPNEPPGLSQGRASSPQVAPQSLNTALLQTLTHLGDISTVLGPLRDQLSTLNQHVEHLRGSFDQTVSLAVGFILGSAASERGILGDLRQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5T230-1", "uniprot_id": "UTF1_HUMAN", "id": "Q5T230-1", "name": "Undifferentiated embryonic cell transcription factor 1", "aln": "MLLRPRRPPPLAPPAPPSPASPDPEPRTPGDAPGTPPRRPASPSALGELG---LPVSPGSAQRTPWSARETELLLGTLLQPAVWRALLLDRRQALPTYRRVSAALAQQQVRRTPAQCRRRYKFLKDKFREAHGQPPGPFDEQIRKLMGLLGDNGRKRPRRRSPGSGRPQRARRPVPNAHAPAPSEPDATPLPTARDRDADPTWTLRFSPSPPKSADASPAPGSPPAPAPTALATCIPEDRAPVRGPGSPPPPPAREDPDSPPGRPEDCAP-PPAAPPSLNTALLQTLGHLGDIANILGPLRDQLLTLNQHVEQLRGAFDQTVSLAVGFILGSAAAERGVLRDPCQ", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******* *.::* ***.***.* *:.**.* *.. *:...:.: * ****.***********************:**:*******:************:********************:*:::***.****:***:*******:* * ****.*.***** *. .* ****: : . . .: :*: :****.*..***.. ..*** *: * ** ..... :*.* * *:.*** .:. *. * .** ********** *****:.:******** *******:***:*****************:***:* * *", "identical_positions": 210, "similar_positions": 72, "identity": "60.87%" }, { "cls_id": "homologset.agr.MGI:1276522", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P01889-1", "uniprot_id": "HLAB_HUMAN", "id": "P01889-1", "name": "HLA class I histocompatibility antigen, B alpha chain", "aln": "--------------------------------------------MLVMAPRT-------VLLLLSAALALTETWAGSHSMRYFYTSVSRPG--RGEPRFISVGYVDDTQFVRFDSDAASPREEPRAPWIEQEGPE-YWDRNTQIYKAQAQTDRESLRNLRGYYNQSEAGSHTLQSMYGCDVGP---DGRLLRGHDQYAYDGKDYIALNEDLRSWTAADTAAQITQRKWEAAREAEQR-RAYLEGECVEWLRRYLENGKDKLERADPPKTHVTHHPISD--HEATLRCWALGFYPAEITLTWQRD-GEDQTQDTELVETRPAGDRTFQKWAAVVVPSG--EEQRYTCHVQHEGLPKPLTLRWEPSS--QSTVPIVGIVAGLAVLAVV---VIGAVVAAVMCRRKSSGGKGGSYSQAACSDSAQGSDVSLTA----------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P10321-1", "uniprot_id": "HLAC_HUMAN", "id": "P10321-1", "name": "HLA class I histocompatibility antigen, C alpha chain", "aln": "--------------------------------------------MRVMAPRA-------LLLLLSGGLALTETWACSHSMRYFDTAVSRPG--RGEPRFISVGYVDDTQFVRFDSDAASPRGEPRAPWVEQEGPE-YWDRETQKYKRQAQADRVSLRNLRGYYNQSEDGSHTLQRMSGCDLGP---DGRLLRGYDQSAYDGKDYIALNEDLRSWTAADTAAQITQRKLEAARAAEQL-RAYLEGTCVEWLRRYLENGKETLQRAEPPKTHVTHHPLSD--HEATLRCWALGFYPAEITLTWQRD-GEDQTQDTELVETRPAGDGTFQKWAAVVVPSG--QEQRYTCHMQHEGLQEPLTLSWEPSS--QPTIPIMGIVAGLAVLVVLA--VLGAVVTAMMCRRKSSGGKGGSCSQAACSNSAQGSDESLITCKA-------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P01893-1", "uniprot_id": "HLAH_HUMAN", "id": "P01893-1", "name": "Putative HLA class I histocompatibility antigen, alpha chain H", "aln": "--------------------------------------------MVLMAPRT-------LLLLLSGALALTQTWARSHSMRYFYTTMSRPG--AGEPRFISVGYVDDTQFVRFDSDDASPREEPRAPWMEREGPK-YWDRNTQICKAQAQTERENLRIALRYYNQSEGGSHTMQVMYGCDVGP---DGPFLRGYEQHAYDGKDYIALNEDLRSWTAADMAAQITKRKWEAARRAEQR-RVYLEGEFVEWLRRYLENGKETLQRADPPKTHMTHHPISD--HEATLRCWALGFYPAEITLTWQRD-GEDQTQDTELVETRPAGDGTFQKWAAVVVPSG--EEQRYTCHVQHEGLPEPLTLRWEPSS--QPTVPIVGIVAGLVLLVAV---VTGAVVAAVMWRKKSSDRKGGSYSQAASSNSAQGSDVSLTA----------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P30511-1", "uniprot_id": "HLAF_HUMAN", "id": "P30511-1", "name": "HLA class I histocompatibility antigen, alpha chain F", "aln": "-----------------------------------------------MAPRS-------LLLLLSGALALTDTWAGSHSLRYFSTAVSRPG--RGEPRYIAVEYVDDTQFLRFDSDAAIPRMEPREPWVEQEGPQ-YWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMNGCDMGP---DGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAEEYAEEF-RTYLEGECLELLRRYLENGKETLQRADPPKAHVAHHPISD--HEATLRCWALGFYPAEITLTWQRD-GEEQTQDTELVETRPAGDGTFQKWAAVVVPPG--EEQRYTCHVQHEGLPQPLILRWEQSP--QPTIPIVGIVAGLVVLGAV---VTGAVVAAVMWRKKSSDRNRGSYSQAAV-----------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I5ZYQ2-1", "uniprot_id": "A0A8I5ZYQ2_RAT", "id": "A0A8I5ZYQ2-1", "name": "Ig-like domain-containing protein", "aln": "--------------------------------------------MRNPIPSTLLLLLLLLLLLLLATLDRTGYCAGSHWLQTFNTVILEPG--MTEPRLIQVSYVDSIQFQGFDSQAPNASMQPRAAWIEQEPPE-YWEKETTQVVSLTLSKGRILRYIANENRHSRN------------------------GNYRLTYYDYDYVTLNEDMISWRAEGEIAKRWLSIWETEGVGESW-MTYLRGTCSERLLRFLELGKKTLLRSDAPKTHLTHQVRPD--GNVTLRCWALGFYPADITLTWQRD-GKNHTQDMELPDTRPAGDGTFQKWAAVMVPSG--EEQRYTCHVHHEGLPEPLTLKWEPS----TTIPIVAILIGLIVVTLV----IGTVVILRVWKK--------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0L3Q2-1", "uniprot_id": "A0ABK0L3Q2_RAT", "id": "A0ABK0L3Q2-1", "name": "Ig-like domain-containing protein", "aln": "--------------------------------------------MRNLIPST----LLLLLLLLLATLDRTGYCAGSHWLQTFNTVILEPG--MTEPRLIQVSYVDSIQFQGFDSQAPNASMQPRAAWIEQEPPE-YWEKETTQVVSLTLSKGRILRYIASGNRHSKNDYRTLQEVFGCNLAN---DGTFLRGDYRLTYYDYDYVTLNEDMISWSAEGEIAKSLLSIWETGGVGESW-MTYLRGTCSERLLRFLELGKKTLLRSDAPKTRLTHQVRPD--GNVTLRCWALGFYPADITLTWQRD-GINHTQDMELPDTRPAGDGTFQKWAAVMVPSG--EEQRYTCHVHHEGLPEPLTLKWEPS----TTIPIVAILIGLIVVTLV----IGTVVYLVVQKK--------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0L2R9-1", "uniprot_id": "A0ABK0L2R9_RAT", "id": "A0ABK0L2R9-1", "name": "", "aln": "--------------------------------------------MKNREPWV------VVLLLLLVTMDLTQYCAGSRWLQTFNTVIAEPR--KSAHQFIQVSYVDSIQFQGFDSQAPNAKMRPRAAWMEQEPPE-YWEKGTAQAPRLSLTNQRVLQFLVIENKHSKNEYHTLQELFGCNVAN---DGSFLRGQYRLTYYGYDNIILNEDLSSWTTEGSAAQDLMKYSETGGMAESW-RTYLLRECTERLIRCLELGKETLLRSYAPQTHLTHQVRPD--GNVTLRCWALGFYPADITLTWQRD-GKNHTQDMELPDTRPAGDGTFQKWAVVIVPSG--EEQRYTCHVHHEGLPEPLTLKWEPS----TTIPIMAILTGLILGTLV----MGTVVYLLVWKK--------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O19443-1", "uniprot_id": "O19443_MOUSE", "id": "O19443-1", "name": "", "aln": "--------------------------------------------MRNTGPCT-------LLLLLMVALDLNHYCAGSHWLQTFNIVILEPG--MLEPRFIQVSYVDSIQYQGFDSKDPSAGMQPRAAWIELEPPE-YWEKETSRVLELSQVERQVLRLMVKKNGHKMDGYHTLQEVYGCNVAN---DGSFLGGHYRLTYYGYDYLTLNEDLSSWTAEGKGAQHAKSRWEDAGEAKRR-KTYLQGECVQRLLRYLDLGKETLLCSDAPQTHVTHHVRPE--GNVTLRCWALGFYPADITMTWKRD-GNNLTQDMELPDTRPAGDGTFQKWAAVVVPSG--EELRYTCHVHHEGLPEPLTLKWEPP----HTIPIIAILIGLVLGTLV----VGTVVIFLVWRK--------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M2BI98-1", "uniprot_id": "A0A8M2BI98_DANRE", "id": "A0A8M2BI98-1", "name": "", "aln": "MFFQKIFLQHIKLSHSKKRETEIFFHGFVIMRTGEFNAETACHSEGEDTHRGFKMAVFVVLLLAVMPLDVEPATTEKHSLYYIYTALSRPVNLPGIHEFTAMGLLDDRQIDYYNSQD--QKKIPKQHWMKEKMQEDYWEKGTQSRKSKEQWFNVNVNILMDRMRHNKSDLHVLQWRHGCEIDSQDDDVRFSKGIDEYSYDGENFLSFDDADSQWVAPVDAALPTKRKWDNVPILNQYTKGYLEKECVDWLNKFREYGNEELREGSPPDVHVFARSIINGKAKLKLTCLATGFYPKDVYLTIRKYRMALLDKDLESSGVRPNHDGTFQLRMSTYIYED--EKAEYDCYVKHRTLGAPIIKKWDGKCSDCSKVTFLGMIVGAIIGAVFVLTVIGLVILVLTRKKGIGDNDPSAIPLNNNQHIEPSVKESKNKPTAAEGQSTGGDLKS-------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AC58HZ21-1", "uniprot_id": "A0AC58HZ21_DANRE", "id": "A0AC58HZ21-1", "name": "", "aln": "--------------------------------------------MADRITQMQK-----MEYILLLVVCLPYVDGATHTWNAYYTATTGLS---QFPEFVAQNLIDGQLMGYFDSKTN--CFKSQFQWMEDKLGTAYDEQQTNILQRHTAKFKNNIKVAIERFN-QTQGVHTLQEIYGCEWDD---QTGNLNAFRQYGYNGEDFLTLDFMEMRWITPVQQAMITTQKWNNDRGFIESDMNYFRSECIEWLQKYLEYGKSSLMKTVSPQVSVLQKYYFS-----PVVCHATGFYPSGIKISWQKN-GQDHDEDVELGELLPNADGTFQKRSTLNVKPEEWKNSKFSCVVEHQGERILTEDEIRTNN----PSATIGIIIGIVLSAVLLL-FIAVAGFVVYWKKKGFKPVPANPSDSVAEKTKSQTSVNSDNDSGCGSGSDSVSHKSSDSTSDISSVCSDNSSDSTTALLPENSDKNSGCDSGSDSVSHKSSDSTSDISSVCSDNSSDSTTALF", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : .: . :*. ::*. .: *:: : * : * :. . . . * . : : :: * : * : *: : * : : *:. * .*.. : : . : * * **** : :: :: :* * * * *** : :: .: * :.*. . :.:: * : . . . :: ", "identical_positions": 29, "similar_positions": 67, "identity": "5.66%" }, { "cls_id": "homologset.agr.MGI:1276523", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GLM3-1", "uniprot_id": "A0A8I6GLM3_RAT", "id": "A0A8I6GLM3-1", "name": "Nuclear receptor coactivator", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSGLGDSSSDPANPDSHKRKGSPCDTLAS-------STEKRRREQENKYLEELAELLSANISDIDSLSVKPDKCKILKKTVDQIQLMKRMEQEKS---TTDDD-----------------------------------------VQKSDISSSSQGVIEKESLG-------------PLLLEALDGFFFVVNCEGRIVFVSENVTSYLGYNQEELMNTSVYSILHVGDHAEFVKNLLPKSLVN------------------------------------------------GVPWPQEATRRNSHTFNCRMLIHPP-----DEPGTENQEACQRYEVMQCFTVSQPKSIQEDGEDFQSCLICIARRLPRPPAITG-VESFMTKQ---------DTTGKIISIDTSSLRAAGRTGWEDLVRKCIYAFFQPQGREPSYARQLFQEVMTRGTASSP-----------SYRFILNDG-TMLSAHTKCKLCYPQSPDMQPFIMGIHIIDREHSGLSPQDDTNSG-------MSIPRINPSVNPGISPAHGVTRSSTLPPSNNNMVSARANRQQSTDLN-SGSSHSNSSSSQGSFGCSPGNQIVASVALSQGQAGSQSSNPSLNLNNSPMEGTGISLAQFMSPRR-QANSGLATRARMSNNSFPPNIPTLSSPVGITSGACSNNNRSYSNIPVTSLQGMNEGPNNSVGFSAGSPVLRQMSSQNSPSRLSMQPAKAESKDNKE--------IASILNEMIQSDNS---ANEGKPLDSGLLHNNDRLSDGDSKYSQTSHKLVQLLTTTAEQQLRHADIDTSCKDVLSCTGTSSSASSNPSGGTCPSSHSSLTERHKILHRLLQEGSPSDITTLSVEPEKKDSASASTAMSVSGQAQGSASIKLELDASKKKESKD-------------HQLLRYLLDKD--EKDLRSTP---NLSLDDVKVKVEKKEQMD--PCNTNPAPVTKPAPEEVKLESQSQFS--ADLDQFDQLLPTLEKAAQLPGLCETDRMDGAVPGVNIKSEILPASLQPTP---------------------ARSAPRLNRLPELELEAIDNQFGQPGAGDQIPWANNTVTAINQ--------------------------------SKPEDQCISSQLDELLCPPTTVEGRNDEKALLEQLVSFLSGKDETELAELDRALGIDKLVQGGGLDVLSER-------------------FPPQQATPPLMMEDRPTLYPQPY-SSPSPTAGLSGPFQGMVR------------------------------QKPSLGTMPVQVTPPRGTFSPNMGMQPRQTLNRPPAAPNQLRLQLQQRLQGQQQLMHQNRQAILN-------------------------------------------QFAANAPVGMNMRSGMQQ-QITPQ------PPLN---AQMLAQRQRELYSQQHR----QRQIIQQQRAMLMRHQSFGNNIPPSSGLP--VQMGNPRLPQGAPQQFPYPPNYGTNPGTPPASTSPFSQLAAN----------------PEASLATRSSMVNRGMAG---------------NMGGQFGTGISPQ---------------MQQNVFQYPG-SGLVPQAEANFAPSLSPGSSMVPMPIPP-QSSLLQQTPPTSGYQSPDMKAWQQGTMGNNNVFSQAVQ-SQPAPAQPGVYNNMSITVSMAGGNANVQNMNPMMGQMQMSSLQMPGMNTVCSEQMNDPALRHTGLYCNQLSSTDLLKTEADGNQQVQQLQVFADVQCTVNLVGGDP------------------------YLNQPGPLGTQKPTSGPQTPQAQQKSLLQQLLTE--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70365-1", "uniprot_id": "NCOA1_MOUSE", "id": "P70365-1", "name": "Nuclear receptor coactivator 1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSGLGDSSSDPANPDSHKRKGSPCDTLAS-------STEKRRREQENKYLEELAELLSANISDIDSLSVKPDKCKILKKTVDQIQLMKRMEQEKS---TTDDD-----------------------------------------VQKSDISSSSQGVIEKESLG-------------PLLLEALDGFFFVVNCEGRIVFVSENVTSYLGYNQEELMNTSVYSILHVGDHAEFVKNLLPKSLVN------------------------------------------------GVPWPQEATRRNSHTFNCRMLIHPP-----EDPGTENQEACQRYEVMQCFTVSQPKSIQEDGEDFQSCLICIARRLPRPPAITG-VESFMTKQ---------DTTGKIISIDTSSLRAAGRTGWEDLVRKCIYAFFQPQGREPSYARQLFQEVMTRGTASSP-----------SYRFILNDG-TMLSAHTKCKLCYPQSPDMQPFIMGIHIIDREHSGLSPQDDSNSG-------MSIPRINPSVNPGISPAHGVTRSSTLPPSNNNMVSARVNRQQSSDLN-SSSSHTNSSNNQGNFGCSPGNQIVANVALNQGQAGSQSSNPSLNLNNSPMEGTGIALSQFMSPRR-QANSGLATRARMSNNSFPPNIPTLSSPVGITSGACNNNNRSYSNIPVTSLQGMNEGPNNSVGFSAGSPVLRQMSSQNSPSRLSMQPAKAESKDSKE--------IASILNEMIQSDNSDNSANEGKPLDSGLLHNNDRLSEGDSKYSQTSHKLVQLLTTTAEQQLRHADIDTSCKDVLSCTGTSSSASSNPSGGTCPSSHSSLTERHKILHRLLQEGSPSDITTLSVEPEKKDSVPASTAVSVSGQSQGSASIKLELDAAKKKESKD-------------HQLLRYLLDKD--EKDLRSTP---NLCLDDVKVKVEKKEQMD--PCNTNPTPMTKPAPEEVKLESQSQFT--ADLDQFDQLLPTLEKAAQLPSLCETDRMDGAVTGVSIKAEVLPASLQPTT---------------------ARAAPRLSRLPELELEAIDNQFGQPGAGDQIPWANNTLTTINQ--------------------------------NKPEDQCISSQLDELLCPPTTVEGRNDEKALLEQLVSFLSGKDETELAELDRALGIDKLVQGGGLDVLSER-------------------FPPQQATPPLMMEDRPTLYSQPY-SSPSPTAGLSGPFQGMVR------------------------------QKPSLGAMPVQVTPPRGTFSPNMGMQPRQTLNRPPAAPNQLRLQLQQRLQGQQQLMHQNRQAILN-------------------------------------------QFAANAPVGMNMRSGMQQ-QITPQ------PPLN---AQMLAQRQRELYSQQHR----QRQIIQQQRAMLMRHQSFGNNIPPSSGLP--VQMGTPRLPQGAPQQFPYPPNYGTNPGTPPASTSPFSQLAAN----------------PEASLATRSSMVNRGMAG---------------NMGGQFGAGISPQ---------------MQQNVFQYPG-PGLVPQGEATFAPSLSPGSSMVPMPVPPPQSSLLQQTPPTSGYQSPDMKAWQQGTMGNNNVFSQAVQ-SQPAPAQPGVYNNMSITVSMAGGNANIQNMNPMMGQMQMSSLQMPGMNTVCSEQMNDPALRHTGLYCNQLSSTDLLKTDADGNQQVQQVQVFADVQCTVNLVGGDP------------------------YLNQPGPLGTQKPTSGPQTPQAQQKSLLQQLLTE--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15788-1", "uniprot_id": "NCOA1_HUMAN", "id": "Q15788-1", "name": "Nuclear receptor coactivator 1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSGLGDSSSDPANPDSHKRKGSPCDTLAS-------STEKRRREQENKYLEELAELLSANISDIDSLSVKPDKCKILKKTVDQIQLMKRMEQEKS---TTDDD-----------------------------------------VQKSDISSSSQGVIEKESLG-------------PLLLEALDGFFFVVNCEGRIVFVSENVTSYLGYNQEELMNTSVYSILHVGDHAEFVKNLLPKSLVN------------------------------------------------GVPWPQEATRRNSHTFNCRMLIHPP-----DEPGTENQEACQRYEVMQCFTVSQPKSIQEDGEDFQSCLICIARRLPRPPAITG-VESFMTKQ---------DTTGKIISIDTSSLRAAGRTGWEDLVRKCIYAFFQPQGREPSYARQLFQEVMTRGTASSP-----------SYRFILNDG-TMLSAHTKCKLCYPQSPDMQPFIMGIHIIDREHSGLSPQDDTNSG-------MSIPRVNPSVNPSISPAHGVARSSTLPPSNSNMVSTRINRQQSSDLH-S-SSHSNSSNSQGSFGCSPGSQIVANVALNQGQASSQSSNPSLNLNNSPMEGTGISLAQFMSPRR-QVTSGLATRPRMPNNSFPPNISTLSSPVGMTSSACNNNNRSYSNIPVTSLQGMNEGPNNSVGFSASSPVLRQMSSQNSPSRLNIQPAKAESKDNKE--------IASILNEMIQSDNS---SSDGKPLDSGLLHNNDRLSDGDSKYSQTSHKLVQLLTTTAEQQLRHADIDTSCKDVLSCTGTSNSASANSSGGSCPSSHSSLTERHKILHRLLQEGSPSDITTLSVEPDKKD--SASTSVSVTGQVQGNSSIKLELDASKKKESKD-------------HQLLRYLLDKD--EKDLRSTP---NLSLDDVKVKVEKKEQMD--PCNTNPTPMTKPTPEEIKLEAQSQFT--ADLDQFDQLLPTLEKAAQLPGLCETDRMDGAVTSVTIKSEILPASLQSAT---------------------ARPTSRLNRLPELELEAIDNQFGQPGTGDQIPWTNNTVTAINQ--------------------------------SKSEDQCISSQLDELLCPPTTVEGRNDEKALLEQLVSFLSGKDETELAELDRALGIDKLVQGGGLDVLSER-------------------FPPQQATPPLIMEERPNLYSQPY-SSPSPTANLPSPFQGMVR------------------------------QKPSLGTMPVQVTPPRGAFSPGMGMQPRQTLNRPPAAPNQLRLQLQQRLQGQQQLIHQNRQAILN-------------------------------------------QFAATAPVGINMRSGMQQ-QITPQ------PPLN---AQMLAQRQRELYSQQHR----QRQLIQQQRAMLMRQQSFGNNLPPSSGLP--VQMGNPRLPQGAPQQFPYPPNYGTNPGTPPASTSPFSQLAAN----------------PEASLANRNSMVSRGMTG---------------NIGGQFGTGINPQ---------------MQQNVFQYPG-AGMVPQGEANFAPSLSPGSSMVPMPIPPPQSSLLQQTPPASGYQSPDMKAWQQGAIGNNNVFSQAVQ-NQPTPAQPGVYNNMSITVSMAGGNTNVQNMNPMMAQMQMSSLQMPGMNTVCPEQINDPALRHTGLYCNQLSSTDLLKTEADGTQQVQQVQVFADVQCTVNLVGGDP------------------------YLNQPGPLGTQKPTSGPQTPQAQQKSLLQQLLTE--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PTD7-1", "uniprot_id": "A0A8M9PTD7_DANRE", "id": "A0A8M9PTD7-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLKMSAAGENALDPNILESRKRKGSPCDTSGP-------SVEKRRRELECRYIDELAELLSANMSDIASLNVKPDKCHILKSTVDQIQQIKRREQENAALMSPNDE-----------------------------------------VQQSDISSSSHGMVEKEALG-------------PLLLEALDGFFFVVNREGRIVFVSENVTGYLGYTQEELMTSSVYSILHVGDHNEFVRILLPKSLVN------------------------------------------------GVPWSQEQGRRNSHTFNCRLLKRPP-----DEVDSENQEARQQYELMQCFTVSQPKALQEEGEDLQSCLICIACRIPRPPQIPVSTESFITKQ---------DPTGKIISIETSALRATGRPGWEDLVRKCIYAFFQPQGNEPSHAKKLLHEVMTHGMAISP-----------LYRFTLSDG-TSLSAQTRCKFCCPQNPDVQPFIMGFHTIDREHNTASSQENTTPS-------LSSPAAPPSRSPALQPSSDLS----IHLNNTNGTCATPGPLTPT---------------------PPGYLTPSRVGPSQ-----QVSSPSP--LGSPLTAT---PTSFMSPRPPRGSPGLASSPRVPGHPFSPSTPSIHSPAGG----------------LTRQQSGGDG----VGFSLPSPLPPRQTPTPSSSPARQPPAKPPEASNDE--------PKSN-----QVGNP---------------------------------KLSQLLDGASAPEQ-------------------DSQPRPSPTSQCPASHSSLTERHKILHRLLQDNSPADAG---KEPDIKKEPPTSPNSALIARGLG-------------KEPQD-------------HQLLRFLLDTD--EKDLEDLPPPATLSLQTVKVKAEKKGSRENVSCAAALANNAMPGSPQSSGKASPQFPS-TDLDTLNQLLPTLRASVGGKTVEEPS-EDSLSIGVNVKRESPGTSSQAFPDGENLSSQTSFDFCDPSTPNQGQSQVQVSDLGQTELFQPPKESSSPFASPTSHNSFNTNTGLAKLELPDSQQFQALPLVEPMTFDNSLANQTQAPLSSPQEQCVPCPLDEMLCPPTTPEGRNDEKALLEQLVTFLSHTDESELAELDRALGIDKIVQSGCLEPVTQTP------------------FPQSQPPTPVPLDPKLPSYPSQFPTSPSQFPAEMATAQGMSF------------------------------GAP-------RMPFPGNVVQAGMNRAPG-VSNQLRLPPNQLRLQLQQRLQGPQQLQN--RLAAMG-------------------------------------------SFPQGGHVAMGMRQSIQQPQMPSQ------PPLN---AQMMAQRQREVYSYQHR----QRQLLQQK-VMLMR-QGINTGPLGAQRLPKGPQQQQQQPPPQQQQQFGFPPGYNAVPGNTPTSPSHFNPMGGP----------------LDPKLSVRAGLGNQGIMG---------------AIQGQFGGPVNTP---------------VQQGLFQQFGGSGMIQQADPSFAPELSPTSPLLSPQNSTSQSPLLQQTQPPPGYQSPDLKTWQQGTVANNGMYNQVGPPVSQSFGQQGVYNNMSITVSMAGGSGAVNTLPPIGPSVGMGNNNLGNVTTMC-------------------------------NEQVQQVQVFADVQCTVNLVGSDS------------------------YLNQSGPIGSQKGPSGTPSAQSQQKSLLQQLLTE--------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9ND53-1", "uniprot_id": "M9ND53_DROME", "id": "M9ND53-1", "name": "", "aln": "MSIAAAENAGLSPSDLPDHWASGTSNPSTSTSSSSSSSISASGSNNNKYNSGNISVCNLPRSSPAAATAAVTLSSAAGGIGSNLLSGLHHGLAPGTHPLQRATAASGGGAGAGGVAGASTAAALTLQQHQHQQQQQQQQQQAQHQHQHQHQQQTQQQQLAYQHQQLQQQIISHRSIQNKAAATAAAQTANLAAALQRSAAIMNAVASPISANSANSATSGRKIRRKTDSKVNLPQSQINKCNNEKRRREAENGYIEQLSEILTLNK-RGDMTSTKPDKAAILNQVVRTYREICDKGQNRDISSTSTNNNNSTTTTNNNTNSNNNNNTSKPQATSTRCSRCATDNCSIHPVQQGEVSSTEPPLPEPSLLLGQVPEISAYFEALEHYISGVGWVLLQVNANGIIESCTQNIRDLIGYEKQELYHQPLYMYLYSGDHAKLEPIINTMYNNPNGGNSNSANNSGPGGSSAGTSAGVWGDLEELNNGNASQGSNSSGAGGLGGAGGAAAGKKRSISTKVRMLVKDTRTATQTSSNCEEKPLRQSGHQDKYEEVVLIAAPVKDDADASSSVLCLITRPEDESPLEINIQQHVQQQPIEQMTFKLDIHGKILTLDPTALREPFKQHLQTWVGRLWQDLCHP--HDLSTLKSHLRDIQDSASANSPGAGAGTSVVSRPFRLRLGAPDVYVHVKANSRLFLNQTPGEGDFIMSVQTLLNSENDMNSSNTGAGSGGLGLGQLCAMAPSPSLASSLLSSLSMDGLHGGTGSGSSSSPAASGMLPTHLLGGLVGGGQQGGGGNSTQTTSVGGPLMSSAIINGTGLQQQQQQQQRSGASSSASSSANALVNAFTASPAPAEHSFYGSDTFEFDIAAHSSSFELDPSGGVGAWTDSRPNSRASVATPVSTPRPPSGHGFSPAVCASPATPYQLSSHSAASLPSPQSNASAGGGNYGGFNFHSFDSSDVKPEKDVQQQQNQQQSNNNSSSSNPLLGGGLPNGVGGMLLSQQQQQQQTPPQQQQQQQQQESSERLRHLLTKSQSMAGGLGGLGDDEKYFKPEGSEEEKHASGGFKMGGQPGGMGMFGPMGSMGRGVGNSSMLHKAGNSQNPMLLKLLNEKSEDDDGNGSGGGPGSMNNSRQSELMRQLKNPDGGSHGMHRNSASGNMSTEDLKAMLKIQSDPSLNRKRSLNEPDDDPSAKRSEDKPSKLCTQNKMLAKLLQNPPKIPKAPNPEQPLQVKTLPDITSSTVSSTLAAPGNLISAG-------------STGPKAAANRNRKQQQQQQQQQQQQQQQQVAGIPSQQQQQQPNDVYLSQQQQQQLQSPQ------------LAFQHQQLATTATTSITTAASTSAAAAAAAAILGEGDSELSKLLDSVMEYYPDDTPIVTNAPSEASAINDIQKSLMLDVESAAFGNDLNQQLMMTQQQQHQQQQQQQQLLALQLAQQQQQQRQQHLQQPPAYPGMLNMQQQQHQQQQQQNQQHIMQRLEAMRNQGNQGFQRPPPMYPARGRGPMNAVATPGGVVLPAQQQLRNIRQQQQLAAAQQKERLLQQQQKQQLLVPENASEYWGNSNLQLIIKLIVSYILAGMNAGLNNIGSLLNTTGAPNVSLSRTNLPSDAQLSPNFAQTLMQQQLSPGRSAPYSPQPNQGYAPQFPQPGQRLSPQQQQQLSQQQQNNVQQQQLAYQQQQVGDGGRSNTPFGSNSGMQSPGMQ-NSPQQWGSGGGGGGGPGGPLPSGNAGRTLQQHNPMLIAQLQGVSPYNARQYQQNQRRGLNSPGAVGPGGNPAAQAALQRQNSFQGQGGGGATTPDGSGVGFGGPQSPYGTNVNVFQQQQLQRLQRQGSVPQATQHLPGSPRFG--SSPGSSNNTDSSAAAGNQQQQQQQQQQQQQQHQQQQHQQLMNGLSMSPHPHPHPAMMGVGGMGSGGGNGIIGLGGGGGNYGATLGGYGQSQQANDFYGRAQTAGGGGSVAGGNANSEFVKQELRAVVSVRAQQAAAAATGGAGVGGGVAQRGQTPQSPLQQGSVIGGGGGIVGGVNSTNTMGNVTPTGSGNVSNSMLNTPPDPTLSFSFETPDFFTSSATR", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . .: :. : *: : ... . . ****** * *:::*:*:*: * ..****. **:..* : : *:. :. :: **:.::**:. : * . * :..:. .:: ** :* * ::*: . :** ::** .:* *: *** :: : . * . ::.* : : *:* : . . . *:: * . : * : ::. * .*.::*: * . : :..: :* * ***::::.::** . : : * : : :* .: * :. :::: . * ** :*: *. . : .::..:: *.*. ***..: : .... ...: . :. ** ..: .: .: .... : . . . * : . . * .. . .*. .: . ::. .: . . . . . .* * . . ** . *.: ::. ... * : : : * : . . . .. *.:: : ..*.. . *. .. . .: :. :*:* * : * .:.:. . .:. : :*. : : . . : * . . . :.. . * : * *.: : : . . .. . . . : : . : : :: . : . :. : ... . . ... ** .: . **:.:: : . ..* .*:.: :. *: : .* .: : : . . .*. . * * . . . . :: .. * : :* *: * * * . .:. . :. .: . : * *:.. * * * :.* :.: . *:: *:* *: : : * .. . : **: . . ** . .* . : : . * .: . * * : ** * .. : .:** : *.. *.. * *. . .. .* :.: .. . *. : : ** :: ..* . : *.: :**. : : . .*: *. * . ..: *. . :*....:*. . ... .:: :: : *: ", "identical_positions": 157, "similar_positions": 427, "identity": "7.56%" }, { "cls_id": "homologset.agr.MGI:1276533", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WUI9-1", "uniprot_id": "NCOA2_RAT", "id": "Q9WUI9-1", "name": "Nuclear receptor coactivator 2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSGMGENTSDPSRAETRKRKECP-DQLGPSP---KRSTEKRNREQENKYIEELAELIFANFNDIDNFNFKPDKCAILKETVKQIRQIKEQEK--------------------------------------------AAAANIDEVQKSDVSSTGQGVIDKDALG-------------PMMLEALDGFFFVVNLEGNVVFVSENVTQYLRYNQEELMNKSVYSILHVGDHTEFVKNLLPKSMVN------------------------------------------------GGSWTGEPPRRNSHTFNCRMLVKPLPDSEEEGHDNQE---AHQKYETMQCFAVSQPKSIKEEGEDKQSCLICVAR-------RVPMKERPALPSSESFTTRQDLQGKITFLDTSTMRDAMKPGWEDLVRRCIQKFHTQHEGESLSYAKRHHHEVLRQG--------LAFSQIYRFSLSDG-TLVAAQTKSKLIRSQTTNEPQLVISIHMLHREQN------VCVMNPDLT-GQAMGKPLSPMSSSSPARQAMCSGNPGQDVALGSNMN-FPMNGPREQMSMPMGRFGGSGGMNHVSGMQATTPQGSNYALKMN-SPSQSSPGLNPGQPSSVLSPRHRMSPGVAGSPRVPPSQFSPAGSLHSPAGVCSS-------TGNSHSYTNSSLNALQALSEGHGVSLGPSLASPDLKMGNSQNSPVNMNPPPLSKMGSLDSKDCFGLYGEPSEGTTGQAQASCHPEEQKRPNDSSMPQAASEDRAE---------------------------GHSRLHESKGQTKLLQLLTTKSDQME----------PSPLPSSLSDTNKDSTG----SLPGPGSTHGTS----LKEKHKILHRLLQDSSSPVDLAKLTAEATGKELNQESSG-----------------TAPGSEVTVKQEPAS---PKKKENALLRYLLDKDDTKDIGLPEITPKLERLDSKTDPASNTKLIAMKTVKEEVSFEPSDQPGSELDNLEEILDDLQNSQLPQLFPDTRPGAPTGSVDKQAIINDLMQLTADSSP-VTPVGAQKAALRMSQSTFNNPR----PGQLGRLLPNQNLPLDITLQSPTGAGPFPPIRNSSPYSVIPQPGMMGNQGMLGSQGN------------------------------LGNNSTGMIGSSTSRSSMPSGEWAPQ---SPAVRVTCAATTGAMNRP---IQGGMIRNPTASIPMRANSQPGQRQMLQPQVMNIGPSELEMNMGGPQYNQQQAPPNQTAPWPESILP-----------------IDQASFGSQNRHPFGSSPDDLLCPHPAAESPSDEGALLDQLYLALRNFDGLEEIDRALG---------IPELVSQSQAVDPEQFSSQESSMMLEQKPP----VFP-QQYAS-QTQMAQGS--YNPMQDPNFH----TMGQRPNYTTLRMQPRPGLRPTGIVQNQPNQLRLQLQHRLQAQQNRQ----------PLMNQISGVSNVNLTLRPGVPTQAPINAQMLAQRQREILNQHLRQRQM-----HQQQQVQQRTLMMRGQGLNMTPSMVAPTG-LPAAMSNPRIPQANAQQFPFPPNYG----------------------------------------------------------------------ISQQPDPGFTGATTPQSPLMSPRMAHTQSPMMQQSQ-----------------ANPAYQPASDINGWAQGSMGGNSMFSQQSPPHFGQQANTSMYNNN-MNINVSMATNTAGLSNMNQMTGQMSMTSVTSVPTSGLSSMGPEQVNDPALRGSSLFTTNQLPGMDMIKQEGDGSRKYC-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61026-1", "uniprot_id": "NCOA2_MOUSE", "id": "Q61026-1", "name": "Nuclear receptor coactivator 2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSGMGENTSDPSRAETRKRKECP-DQLGPSP---KRSTEKRNREQENKYIEELAELIFANFNDIDNFNFKPDKCAILKETVKQIRQIKEQEK--------------------------------------------AAAANIDEVQKSDVSSTGQGVIDKDALG-------------PMMLEALDGFFFVVNLEGSVVFVSENVTQYLRYNQEELMNKSVYSILHVGDHTEFVKNLLPKSMVN------------------------------------------------GGSWSGEPPRRSSHTFNCRMLVKPLPDSEEEGHDSQE---AHQKYEAMQCFAVSQPKSIKEEGEDLQSCLICVAR-------RVPMKERPTLPSSESFTTRQDLQGKITSLDTSTMRAAMKPGWEDLVRRCIQKFHTQHEGESLSYAKRHHHEVLRQG--------LAFSQIYRFSLSDG-TLVAAQTKSKLIRSQTTNEPQLVISLHMLHREQN------VCVMNPDLT-GQAMGKPLNPISSSSPAHQALCSGNPGQDMTLGSNIN-FPMNGPKEQMGMPMGRFGGSGGMNHVSGMQATTPQGSNYALKMN-SPSQSSPGMNPGQASSVLSPRQRMSPGVAGSPRIPPSQFSPAGSLHSPVGVCSS-------TGNSHSYTNSSLNALQALSEGHGVSLGSSLASPDLKMGNLQNSPVNMNPPPLSKMGSLDSKDCFGLYGEPSEGTTGQAEASCHPEEQKGPNDSSMPQAASGDRAE---------------------------GHSRLHDSKGQTKLLQLLTTKSDQME----------PSPLPSSLSDTNKDSTG----SLPGPGSTHGTS----LKEKHKILHRLLQDSSSPVDLAKLTAEATGKELSQESSS-----------------TAPGSEVTVKQEPAS---PKKKENALLRYLLDKDDTKDIGLPEITPKLERLDSKTDPASNTKLIAMKTVKEEVSFEPSDQPGSELDNLEEILDDLQNSQLPQLFPDTRPGAPTGSVDKQAIINDLMQLTADSSP-VPPAGAQKAALRMSQSTFNNPR----PGQLGRLLPNQNLPLDITLQSPTGAGPFPPIRNSSPYSVIPQPGMMGNQGMLGSQGN------------------------------LGNNSTGMIGSSTSRPSMPSGEWAPQ---SPAVRVTCAATTGAMNRP---VQGGMIRNPTASIPMRANSQPGQRQMLQSQVMNIGPSELEMNMGGPQYNQQQAPPNQTAPWPESILP-----------------IDQASFASQNRQPFGSSPDDLLCPHPAAESPSDEGALLDQLYLALRNFDGLEEIDRALG---------IPELVSQSQAVDAEQFSSQESSIMLEQKPP----VFP-QQYAS-QAQMAQGG--YNPMQDPNFH----TMGQRPNYTTLRMQPRPGLRPTGIVQNQPNQLRLQLQHRLQAQQNRQ----------PLMNQISSVSNVNLTLRPGVPTQAPINAQMLAQRQREILNQHLRQRQM-----QQQ--VQQRTLMMRGQGLNVTPSMVAPAG-LPAAMSNPRIPQANAQQFPFPPNYG----------------------------------------------------------------------ISQQPDPGFTGATTPQSPLMSPRMAHTQSPMMQQSQ-----------------ANPAYQPTSDMNGWAQGSMGGNSMFSQQSPPHFGQQANTSMYSNN-MNISVSMATNTGGLSSMNQMTGQMSMTSVTSVPTSGLPSMGPEQVNDPALRGGNLFP-NQLPGMDMIKQEGDASRKYC-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15596-1", "uniprot_id": "NCOA2_HUMAN", "id": "Q15596-1", "name": "Nuclear receptor coactivator 2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSGMGENTSDPSRAETRKRKECP-DQLGPSP---KRNTEKRNREQENKYIEELAELIFANFNDIDNFNFKPDKCAILKETVKQIRQIKEQEK--------------------------------------------AAAANIDEVQKSDVSSTGQGVIDKDALG-------------PMMLEALDGFFFVVNLEGNVVFVSENVTQYLRYNQEELMNKSVYSILHVGDHTEFVKNLLPKSIVN------------------------------------------------GGSWSGEPPRRNSHTFNCRMLVKPLPDSEEEGHDNQE---AHQKYETMQCFAVSQPKSIKEEGEDLQSCLICVAR-------RVPMKERPVLPSSESFTTRQDLQGKITSLDTSTMRAAMKPGWEDLVRRCIQKFHAQHEGESVSYAKRHHHEVLRQG--------LAFSQIYRFSLSDG-TLVAAQTKSKLIRSQTTNEPQLVISLHMLHREQN------VCVMNPDLT-GQTMGKPLNPISSNSPAHQALCSGNPGQDMTLSSNIN-FPINGPKEQMGMPMGRFGGSGGMNHVSGMQATTPQGSNYALKMN-SPSQSSPGMNPGQPTSMLSPRHRMSPGVAGSPRIPPSQFSPAGSLHSPVGVCSS-------TGNSHSYTNSSLNALQALSEGHGVSLGSSLASPDLKMGNLQNSPVNMNPPPLSKMGSLDSKDCFGLYGEPSEGTTGQAESSCHPGEQKETNDPNLPPAVSSERAD---------------------------GQSRLHDSKGQTKLLQLLTTKSDQME----------PSPLASSLSDTNKDSTG----SLPGSGSTHGTS----LKEKHKILHRLLQDSSSPVDLAKLTAEATGKDLSQESSS-----------------TAPGSEVTIKQEPVS---PKKKENALLRYLLDKDDTKDIGLPEITPKLERLDSKTDPASNTKLIAMKTEKEEMSFEPGDQPGSELDNLEEILDDLQNSQLPQLFPDTRPGAPAGSVDKQAIINDLMQLTAENSP-VTPVGAQKTALRISQSTFNNPR----PGQLGRLLPNQNLPLDITLQSPTGAGPFPPIRNSSPYSVIPQPGMMGNQGMIGNQGN------------------------------LGNSSTGMIGNSASRPTMPSGEWAPQ---SSAVRVTCAATTSAMNRP---VQGGMIRNPAASIPMRPSSQPGQRQTLQSQVMNIGPSELEMNMGGPQYSQQQAPPNQTAPWPESILP-----------------IDQASFASQNRQPFGSSPDDLLCPHPAAESPSDEGALLDQLYLALRNFDGLEEIDRALG---------IPELVSQSQAVDPEQFSSQDSNIMLEQKAP----VFP-QQYAS-QAQMAQGS--YSPMQDPNFH----TMGQRPSYATLRMQPRPGLRPTGLVQNQPNQLRLQLQHRLQAQQNRQ----------PLMNQISNVSNVNLTLRPGVPTQAPINAQMLAQRQREILNQHLRQRQM-----HQQQQVQQRTLMMRGQGLNMTPSMVAPSG-MPATMSNPRIPQANAQQFPFPPNYG----------------------------------------------------------------------ISQQPDPGFTGATTPQSPLMSPRMAHTQSPMMQQSQ-----------------ANPAYQAPSDINGWAQGNMGGNSMFSQQSPPHFGQQANTSMYSNN-MNINVSMATNTGGMSSMNQMTGQISMTSVTSVPTSGLSSMGPEQVNDPALRGGNLFP-NQLPGMDMIKQEGDTTRKYC-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q98TW1-1", "uniprot_id": "NCOA2_DANRE", "id": "Q98TW1-1", "name": "Nuclear receptor coactivator 2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSAVGENSSDPARSEAQKRKEGPSDLLGPSP---KRSTEKRNREHESKYIEELAELIFANFNDIDNFNVKPDKCAILKETVKQIRQIKEQEK--------------------------------------------AAAANEDEVQKADVSSTGQSVIDKDALG-------------PMMLEALDGFFFVVNMEGNIVFVSENVTQYLRYNQEELMNTSVYSILHVGDHAEFIKNLLPKSHVN------------------------------------------------GVPWSSENPRRNSHTFNCRMLVN--PHSEAEETQDHE---AQQKYETMQCFAVSEPKSIKEEGEDFQSCLICVAR-------RVPMKERPMLPTQESFTTRQDLQGKITSLDTSLLRASMKPGWEDLVRRCIQRFHLQNDGD-ISFAKRHQQEVIRHG--------QAFSPIYRFSLSDG-TIVSAHTKSKLVRSSSTNEPQLYMSLHILQREQP------VCGMASDLGNAQTMGKPMNPMSSPNTAGSSCTP--QGQDATISSNTSTFPSPGAQKEPGA-MHRFGCPGTMSHSATMQAATPQGSGYPLKLS-SPSQGSPGM--------LSPRHRASPGVAGSPRLPPPQFSPAGSLHSPASMCTSSTGGNGGAGANHGYTSSSLNALQALSECHGVSHGQSLGSPDRKLGSPAAHSVAVSHHLINKMSVPES---FGEQNQSEQGTPGQDEGIDLPRDEKG----NLGQFGNLDGSD---------------------------PQSRLRDNKSHTKLLQLLTTKTEPIES-------TSPPPMAGGEPGCKDGGAGNGGMGSQGGNGSHATS----LKEKHKILHRLLQNSSSPVDLAKLTAEATGKELCQDSAGG----------------TAGVPELAIKQEPVS---PKKKDNALLRYLLDKDDNVLKGK---GIKMEPGEIKEE---GGKMTGIKTEKTDGGYDRVE-PSSELD---DILDDLQNSQ-PGLFTDSRPVSLPSAVDKQSIINDILQMTGESGANMSPQQQRALQTAVSQQNFPAPR----PGQPGRAPPVRSVSLDMNMPPKGAQGQYPMMRNNNPYSIMQQQGMMGNHAVMPNQPN------------------------------MVN--AGVMGNNGPRVGMQQDGWGAQGTVGSAASPATAAPAGQHSLPQGALHSRMVPNPATGMPMRPNSQPGPRPMLQPQMMANAQSNMDMGMAGHQFPQQQAPPNQTAPWPDSVMP-----------------IEPVPFGNQSSSMYGGSQEDVLCP-PASEGPADEGALLSQLYSALKDFDGLEEIDRALG---------IPALVGQAQPVEQDQFPGQDPSMMMDQKPP----MYGQQQYASSPANMQQAG--YTPMQDATFHGLQGQMGQRPGYPMLRMQARPGLRPGGVVPNQPNTLRLQLQHRLQAQQNRQ----------PMMNQMGGVSNMNLPLRPNVPNQGTINAQMLAQRQRELLSNHLRQRQLDQQRQQQQQQQQQRSLAMRAQGLTMPPNMAAAAAGMPGAMSNPRIPQANLQQFPYPPNYGTGLASPPPSTSPFSPGSPNLPAPQLLSHSAMHGSQMSLANQGMLGSLSGQFGAVMSPQMQHSAFQFPSSGMSQQSDGGFGGAATPQSPLMSPRMGHAQSPMMQQAQ-----------------GNSSFQSSPDMNGWPQGNINTNSMFTQQSPPQFSQQANNNMYNGNGMNLNVSMAANS---SNMGQMGNQMSMSSMNSGPGSGMANMGPEQQ------------------------------KYC-------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9ND53-1", "uniprot_id": "M9ND53_DROME", "id": "M9ND53-1", "name": "", "aln": "MSIAAAENAGLSPSDLPDHWASGTSNPSTSTSSSSSSSISASGSNNNKYNSGNISVCNLPRSSPAAATAAVTLSSAAGGIGSNLLSGLHHGLAPGTHPLQRATAASGGGAGAGGVAGASTAAALTLQQHQHQQQQQQQQQQAQHQHQHQHQQQTQQQQLAYQHQQLQQQIISHRSIQNKAAATAAAQTANLAAALQRSAAIMNAVASPISANSANSATSGRKIRRKTDSKVNLPQSQINKCNNEKRRREAENGYIEQLSEILTLNK-RGDMTSTKPDKAAILNQVVRTYREICDKGQNRDISSTSTNNNNSTTTTNNNTNSNNNNNTSKPQATSTRCSRCATDNCSIHPVQQGEVSSTEPPLPEPSLLLGQVPEISAYFEALEHYISGVGWVLLQVNANGIIESCTQNIRDLIGYEKQELYHQPLYMYLYSGDHAKLEPIINTMYNNPNGGNSNSANNSGPGGSSAGTSAGVWGDLEELNNGNASQGSNSSGAGGLGGAGGAAAGKKRSISTKVRMLVKDTRTATQTSSNCEEKPLRQSGHQDKYEEVVLIAAPVKDDADASSSVLCLITRPEDESPLEINIQQHVQQQPIEQMTFKLDIHGKILTLDPTALREPFKQHLQTWVGRLWQDLCHPHDLSTLKSHLRDIQDSASANSPGAGAGTSVVSRPFRLRLGAPDVYVHVKANSRLFLNQTPGEGDFIMSVQTLLNSENDMNSSNTGAGSGGLGLGQLCAMAPSPSLASSLLSSLSMDGLHGGTGSGSSSSPAASGMLPTHLLGGLVGGGQQGGGGNSTQTTSVGGPLMSSAIINGTGLQQQQQQQQRSGASSSASSSANALVNAFTASPAPAEHSFYGSDTFEFDIAAHSSSFELDP-SGGVGAWTDSRPNSRASVATPVSTPRPPSGHGFSPAVCASPATPYQLSSHSAASLPSPQSNASAGGGNYGGFNFHSFDSSDVKPEKDVQQQQNQQQSNNNSSSSNPLLGGGLPNGVGGMLLSQQQQQQQTPPQQQQQQQQQESSERLRHLLTKSQSMAGGLGGLGDDEKYFKPEGSEEEKHASGGFKMGGQPGGMGMFGPMGSMGRGVGNSSMLHKAGNSQNPMLLKLLNEKSEDDDGNGSGGGPGSMNNSRQSELMRQLKNPDGGSHGMHRNSASGNMSTEDLKAMLKIQSDPSLNRKRSLNEPDDDPSAKRSEDKPSKLCTQNKMLAKLLQNPPKIPKAPNPEQPLQVKTLPDITSSTVSSTLAAPGNLISAGSTGPKAAANRNRKQQQQQQQQQQQQQQQQVAGIPSQQQQQQPNDVYLSQQQQQQLQSPQLAFQHQQLATTATTSITTAASTSAAAAAAAAILGEGDSELSKLLDSVMEYYPDDTPIVTNAPSEASAINDIQKSLMLDVESAAFGNDLNQQLMMTQQQQHQQ--QQQQQQLLALQLAQQQQQQRQQHLQQPPAYPGMLNMQQQQHQQQQQQNQQHIMQRLEAMRNQGNQGFQRPPPMYPARGRGPMNAVATPGGVVLPAQQQLRNIRQQQQLAAAQQKERLLQQQQKQQLLVPENASEYWGNSNLQLIIKLIVSYILAGMNAGLNNIGSLLNTTGAPNVSLSRTNLPSDAQLSPNFAQTLMQQQLSPGRSAPYSPQPNQGYAPQFPQPGQRLSPQQQQQLSQQQQNNVQQQQLAYQQQQVGDGGRSNTPFGSNSGMQSPGMQNSPQQWGSGGGGGGGPGGPLPSGNAGRTLQQHNPMLIAQLQGVSPYNARQYQQNQRRGLNSPGAVGPGGNP-AAQAALQRQNSFQGQGGGGATTPDGSGVGFGGPQSPYGTNVNVFQQQQLQRLQRQGS----------------------VPQATQHLPGSPRFGSSPGSSNNTDSSAAAGNQQQQQQQQQQQQQQHQQQQHQQLMNGLSMSPHPHPHPAMMGVGGMGSGGGNGIIGLGGGGGNYGATLGGYGQSQQANDFYGRAQTAGGGGSVAGGNANSEFVKQELRAVVSVR-AQQAAAAATGGAGVGGGVAQRGQTPQSPLQQGSVIGGGGGIVGGVNSTNTMGNVTPTGSGNVSNSMLNTPPDPTLSFSFETPDFFTSSATR", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :. *:::.: : : *:: . *.. * ..***.** *. ***:*:*:: * * . ****.***::.*: *:* :: : : .. . **:.:**** : : . * :..:. .:: ** :* : ::*: : : *:::** : .:* *: ***::: : . * . . :: * : : ****: : : .* :. :: .* . .:*::.: .* * ::* .: :::: . *.:* : *::*** **.: :* .:* : * * * : :: . :. *. :: . ..* :*: *. . * .:::*:*. ..:..* :: :*:: * ..: . .* .* . . .* : . . * : .*. . . . . : * . .. * *. :: . .* . *. : ..:.** . .* :.::. . :* :* .:*.* *: ::: ... * . . : . :. .: :* * . . . .. * .: . . . :: :.: ::.: :: *: * **:: : . . :. . * . * . ... :. : : :*..*: * *. :: ..: .... .. . ::::..* ..:. :*:*: * . . . . . : . . : : : . . *..* . * *: .* . :. . ..:.. :: * : :. : **. *. . * : .:.:: . . . .... : : ... : . : : : :. :*.. : * * * . . : . : *: ..: : * ::* : : . * * *.. .* * : .. .:. . :::* * *:* .:.. * . : *:: . :* * . : : .. .:* :* .* : * . .:: * . .* *: : *: . : * * *. . .:.. :*: * . * * :.: * * . : .. **: *.**. *.. * :*.:: :. * .*. . * : ...: : **: . * .** : : * : . * * * . . .: . * . *: * .* . .*: :: ..* :* : . . : .: *:. .. .* . :.: . . * . .:. ", "identical_positions": 195, "similar_positions": 482, "identity": "9.4%" }, { "cls_id": "homologset.agr.MGI:1276534", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35855-1", "uniprot_id": "BCAT2_MOUSE", "id": "O35855-1", "name": "Branched-chain-amino-acid aminotransferase, mitochondrial", "aln": "--MAAATLGQVWAR------KLLPVPWLLCGSK--------------------------RCVSS------------IFKAADLQIQMTK--EPQKKPAPSQALLFGKTFTDHMLMVEWNNKA-GWGPPRIQPFQNLTLHPACSGLHYSLQLFEGLKAYKGGDQQVRLFRPWLNMDRMLRSARRLCLPDFDKQELLECIRQLIEVDKDWVPDGNGTSLYVRPVLIGNEPSLGVGMVTQALLYVILCPVGSYFPGDSMTPVSLLADPSFVRAWIGGVGDCKLGGNYGPTVAVQREAQKRGCEQVLWLYGPDHQLTEVGTMNIFVYWTHE-DGVLELVTPPLNGVILPGVVRQSLLDLARTWG---EFRVAERKVTMKELKRALEEGRVREVFGSGTACQVCPVHQILYEGKQLHIPTMENGPE--LILRFQKELKAIQYGASAH-DWMFRV----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O35854-1", "uniprot_id": "BCAT2_RAT", "id": "O35854-1", "name": "Branched-chain-amino-acid aminotransferase, mitochondrial", "aln": "--MSAAILGQVWTR------KLLPIPWRLCVPG--------------------------RCVSS------------NFKAADLQVQVTR--EPQKKPAPSQPLLFGKTFTDHMLMVEWNSKT-GWGPPRIQPFQNLTLHPACSGLHYSLQLFEGLKAYKGRDKQVRLFRPWLNMDRMLRSARRLCLPDFDKQELLECIRQLIEVDKDWVPDGNGTSLYVRPVLIGNEPSLGVGMVTQALLFVILCPVGSYFPGDSMTPVSLLADPSFVRAWIGGVGDCKLGGNYGPTVAVQQEAQKKGCEQVLWLYGPDHQLTEVGTMNIFVYWTHE-DGELELATPPLDGIILPGVVRQSLLDLARTWG---EFRVAERKVTMKELKRALEEGRVREVFGSGTACQVCPVHQILYEGKQLHIPTMENGPE--LILRFQKELKAIQYGTSAH-DWMLRV----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O15382-1", "uniprot_id": "BCAT2_HUMAN", "id": "O15382-1", "name": "Branched-chain-amino-acid aminotransferase, mitochondrial", "aln": "--MAAAALGQIWAR------KLLSVPWLLCGPR--------------------------RYASS------------SFKAADLQLEMTQ--KPHKKPGPGEPLVFGKTFTDHMLMVEWNDK--GWGQPRIQPFQNLTLHPASSSLHYSLQLFEGMKAFKGKDQQVRLFRPWLNMDRMLRSAMRLCLPSFDKLELLECIRRLIEVDKDWVPDAAGTSLYVRPVLIGNEPSLGVSQPTRALLFVILCPVGAYFPGGSVTPVSLLADPAFIRAWVGGVGNYKLGGNYGPTVLVQQEALKRGCEQVLWLYGPDHQLTEVGTMNIFVYWTHE-DGVLELVTPPLNGVILPGVVRQSLLDMAQTWG---EFRVVERTITMKQLLRALEEGRVREVFGSGTACQVCPVHRILYKDRNLHIPTMENGPE--LILRFQKELKEIQYGIRAH-EWMFPV----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E9QFU8-1", "uniprot_id": "E9QFU8_DANRE", "id": "E9QFU8-1", "name": "Branched-chain-amino-acid aminotransferase", "aln": "----MAALRTAVNG------RFLHPLSLSCGSL--------------------------RFVSS------------SFKAADLTIEKSS--VLKPKPDPS-TLVFGKQFSDHMLTISWSAAG-GWENPQIKPFQNLSLHPACSALHYSIELFEGMKAFRGVDNNIRLFRPMLNMERMHRSAERSCLPLFDKAELLKCINKLVETDQEWVPYSTDASLYIRPTFIGTEPSLGVSRAGHALLFVIVGPVGPYFATGSFNPVSLLADPRYVRAWRGGVGEYKMGGNYGPTIAVQNEAAKQGCQQVLWLYGESEEITEVGTMNLFIYWTTK-KGEKELVTPPLDGVILPGVTRQSLLDLAREWG---EFKVTERRVFMKELLGALDEGRVLEVFGSGTACVVCPVGSLLYKGQTYQIPTMKNGPD--LAKRFHKELTDIQYGRLQR-DWAPLVV---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VYD5-1", "uniprot_id": "Q9VYD5_DROME", "id": "Q9VYD5-1", "name": "Branched-chain-amino-acid aminotransferase", "aln": "MTTKMAINAKDIFRNQHRLIRFLEQSIRLCSNQSLKAAQAAQLQQKSSADFEITASLDAQYTSAPEPIKHDKNLGHQFRASQISVRLAAPEQLQPKPDNDEELGFGRLFTDHMLKIYYHKSLGGWQRPEITPLENLVMHPAAKVLHYAVELFEGMKAYRGVDGKIRIFRPDMNMNRMNLAAQRSGLPTFEGKEFVQCLSRLLSIDSEWVPHTDTASLYIRPTLIGIDPTLGVASSDSALLYTILSPVGSYFKTGSSGAVSLLADPSYVRAWPGGVGNRKMGSNYAPTINVQKEAAAKGLQQVLWLYGEDHQLTEVGTMNIFMFFVND-QGEQELVTPPLSGLILPGITRDSILRMTRQWG---KFKVSEANITMPMVCELLNQGRLLELFGAGTACVVSPVNRISYLGQDLYIPTMEQEKP--VHELIRETLTDIQYGRVDH-PWAVVID---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38891-1", "uniprot_id": "BCA1_YEAST", "id": "P38891-1", "name": "Branched-chain-amino-acid aminotransferase, mitochondrial", "aln": "----MLQRHSLKLG------KFSIRTL-ATGAP--------------------------------------------LDASKLKITRNP---NPSKPRPNEELVFGQTFTDHMLTIPWSAKE-GWGTPHIKPYGNLSLDPSACVFHYAFELFEGLKAYRTPQNTITMFRPDKNMARMNKSAARICLPTFESEELIKLTGKLIEQDKHLVPQGNGYSLYIRPTMIGTSKGLGVGTPSEALLYVITSPVGPYYKTG-FKAVRLEATDYATRAWPGGVGDKKLGANYAPCILPQLQAAKRGYQQNLWLFGPEKNITEVGTMNVFFVFLNKVTGKKELVTAPLDGTILEGVTRDSVLTLARDKLDPQEWDINERYYTITEVATRAKQGELLEAFGSGTAAVVSPIKEIGWNNEDIHVPLLPGEQCGALTKQVAQWIADIQYGRVNYGNWSKTVADLN", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P47176-1", "uniprot_id": "BCA2_YEAST", "id": "P47176-1", "name": "Branched-chain-amino-acid aminotransferase, cytosolic", "aln": "----------------------------MTLAP--------------------------------------------LDASKVKITTTQ---HASKPKPNSELVFGKSFTDHMLTAEWTAEK-GWGTPEIKPYQNLSLDPSAVVFHYAFELFEGMKAYRTVDNKITMFRPDMNMKRMNKSAQRICLPTFDPEELITLIGKLIQQDKCLVPEGKGYSLYIRPTLIGTTAGLGVSTPDRALLYVICCPVGPYYKTG-FKAVRLEATDYATRAWPGGCGDKKLGANYAPCVLPQLQAASRGYQQNLWLFGPNNNITEVGTMNAFFVFKDSKTGKKELVTAPLDGTILEGVTRDSILNLAKERLEPSEWTISERYFTIGEVTERSKNGELLEAFGSGTAAIVSPIKEIGWKGEQINIPLLPGEQTGPLAKEVAQWINGIQYGETEHGNWSRVVTDLN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *:.: : ** . * **: *:**** : ** *.* * ** :.*:. :**:.:****:**:: : : :*** ** ** :* * ** *: *:: :*:. *. ** ***:**.:** ***. ***:.* ***.*: . .* * * *** ** *: *:*.**.* : * :* :* :* ***:* ..::******* *. : . * **.*.**.* ** *:.*:*:* ::: :: : * : : .:*.: * **:***. *.*: : : .. :* : : . : : **** * : ", "identical_positions": 121, "similar_positions": 92, "identity": "26.71%" }, { "cls_id": "homologset.agr.MGI:1276535", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9EPU2-1", "uniprot_id": "NCOA3_RAT", "id": "Q9EPU2-1", "name": "Nuclear receptor coactivator 3", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IIRRCIQRFFSLNDGQSWSQKRHYQEAYIHGHAETP-----------VYRFSLADG-TIVSAQTKSKLFRNPVTNDRHGFVSTHFLQREQNGCRPNPILQDKGIR---------------------PPAAGC-----GMSLSPSQSVQMLGSRTYGVADPSNTGQMAGARYGASSSVASLTPGQSLQSPSSYQSN-------------------------------------------------SYGLNMSSPPHGSPGLGPNQQNIMISPRNRGSPKMAS-------------HQFSPAAGVHSPMG------SSGNTG---SHSFSSSSLSALQAISEG----------------VGTSLLS-----TLSSPGPKLDNSPNMNINQPS--------KASSQDSKSPLGLYCEQNPVESSVCPSNSRDPPVTKENKENSGEASETPRGPLESKG----------------HKKLLQLLTCSSDDR-------GHSSLTN--------SPLDSN------CKDSSISVTSPS--GVSSS------------TSGAVSSTSNMHG----SLLQEKHRILHKLLQNG---------NSPAEVAKITAEATGKDTSSTASGGEG-------------------SVXQEQLSPXK-KENNALLRYLLDRDDPSDVLAKELQPQADGGDSK--LSQCSCXTNPSSGQEKDPKIKTE---EVSGDLDN-----LDAILGDLTSSD---FYNS--PTNGSHPGAKQQMFAGPSSLGLRSPQPVQSVRPPYNRALSLDSPVSVGSVPPVKNVSAFPVLPKQPILAGNPRMMDSQENYGANMGGPNRNVPVNPTSSSGDWGLANSRASRMEPLASSPLGRAGGDYSAALPRPALGSSGPTLPLRSNRLPGARPTL--------------------------MLQMRAGEVPMGMGVSPYSPAVPSNQPG--SWPEGMLSMEQGPHGAQNRPLLRNSLDELLGPPSNPEGQSDERALLDQLHTLLSNTDATGLEEIDR-ALGIPELVSQGQALE--SKQDVFQ----GQEAAVMMDQKA--ALYGQTYPAQGPP-LQGGFH-------------LQGQS-PSLNSMMSQISQQGSFPLQG----LHPRASMVRPRTNTPKQLRMQLQQRLQGQ-----------------------QFLNQSRQALEMKMESPTG--AAVMRPMLQS----QQAFFNAQMAAQQKRELMNHH--LQQQRMAMMMSQPQ-------------------------PQAFSPPPNVTASPSMDGVLAGSAMPQAPPQQFPYATNYGMGQPPEPAFG-RGSSPPSAMMSSRMGPSQN-AMVQHPQTAPMYQSSEMKGWPSGNLARNGS-----------FPQQQFAPQANPAAYNMVHMNSSGSHLGQMTMTPMPMSGMPMGPDQKYC---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O09000-1", "uniprot_id": "NCOA3_MOUSE", "id": "O09000-1", "name": "Nuclear receptor coactivator 3", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSGLGESSLDPLAAESRKRKLPCDAP----GQGLVYSGEKWRREQESKYIEELAELISANLSDIDNFNVKPDKCAILKETVRQIRQIKEQGKT---------------------------------------------ISSDDDVQKADVSSTGQGVIDKDSLG-------------PLLLQALDGFLFVVNRDGNIVFVSENVTQYLQYKQEDLVNTSVYSILHEPRRKDFLNTY---------QNPQLMEFLGLMRTRD---------------------------------------KKAPYILIVRMLMKT-HDILEDVNASPETRQRYETMQ--CFALSQPRAMLEEGEDLQCCMICVARR--------VTA---PFPSSPESFITRHDLSGKVVNIDTN-SLRSSMRPGFEDIIRRCIQRFFSLNDGQSWSQKRHYQEAYVHGHAETP-----------VYRFSLADG-TIVSAQTKSKLFRNPVTNDRHGFISTHFLQREQNGYRPNPIPQDKGIR---------------------PPAAGC-----GVSMSPNQNVQMMGSRTYGVPDPSNTGQMGGARYGASSSVASLTPGQSLQSPSSYQNS-------------------------------------------------SYGLSMSSPPHGSPGLGPNQQNIMISPRNRGSPKMAS-------------HQFSPAAGAHSPMG------PSGNTG---SHSFSSSSLSALQAISEG----------------VGTSLLS-----TLSSPGPKLDNSPNMNISQPS--------KVSGQDSKSPLGLYCEQNPVESSVCQSNSRDPQVKKESKESSGEVSETPRGPLESKG----------------HKKLLQLLTCSSDDR-------GHSSLTN--------SPLDPN------CKDSSVSVTSPS--GVSSS------------TSGTVSSTSNVHG----SLLQEKHRILHKLLQNG---------NSPAEVAKITAEATGKDTSSTASCGEG-------------------TTRQEQLSPKK-KENNALLRYLLDRDDPSDVLAKELQPQADSGDSK--LSQCSCSTNPSSGQEKDPKIKTETNDEVSGDLDN-----LDAILGDLTSSD---FYNN--PTNGGHPGAKQQMFAGPSSLGLRSPQPVQSVRPPYNRAVSLDSPVSVGSGPPVKNVSAFPGLPKQPILAGNPRMMDSQENYGANMG-PNRNVPVNPTSSPGDWGLANSRASRMEPLASSPLGRTGADYSATLPRPAMGGSVPTLPLRSNRLPGARPSLQQQQQQQQQQQ---QQQQQQQQQQQQMLQMRTGEIPMGMGVNPYSPAVQSNQPG--SWPEGMLSMEQGPHGSQNRPLLRNSLDDLLGPPSNAEGQSDERALLDQLHTFLSNTDATGLEEIDR-ALGIPELVNQGQALE--SKQDVFQ----GQEAAVMMDQKA--ALYGQTYPAQGPP-LQGGFN-------------LQGQS-PSFNSMMGQISQQGSFPLQG----MHPRAGLVRPRTNTPKQLRMQLQQRLQGQ-----------------------QFLNQSRQALEMKMENPAG--TAVMRPMMP------QAFFNAQMAAQQKRELMSHH--LQQQRMAMMMSQPQ-------------------------PQAFSPPPNVTASPSMDGVLAGSAMPQAPPQQFPYPANYGMGQPPEPAFG-RGSSPPSAMMSSRMGPSQN-AMVQHPQPTPMYQPSDMKGWPSGNLARNGS-----------FPQQQFAPQGNPAAYNMVHMNSSGGHLGQMAMTPMPMSGMPMGPDQKYC---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y6Q9-1", "uniprot_id": "NCOA3_HUMAN", "id": "Q9Y6Q9-1", "name": "Nuclear receptor coactivator 3", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSGLGEN-LDPLASDSRKRKLPCDTP----GQGLTCSGEKRRREQESKYIEELAELISANLSDIDNFNVKPDKCAILKETVRQIRQIKEQGKT---------------------------------------------ISNDDDVQKADVSSTGQGVIDKDSLG-------------PLLLQALDGFLFVVNRDGNIVFVSENVTQYLQYKQEDLVNTSVYNILHEEDRKDFLKNL---------PKSTVNGVSWTNETQR---------------------------------------QKS-HTFNCRMLMKTPHDILEDINASPEMRQRYETMQ--CFALSQPRAMMEEGEDLQSCMICVARR--------ITTGERTFPSNPESFITRHDLSGKVVNIDTN-SLRSSMRPGFEDIIRRCIQRFFSLNDGQSWSQKRHYQEAYLNGHAETP-----------VYRFSLADG-TIVTAQTKSKLFRNPVTNDRHGFVSTHFLQREQNGYRPNPNPVGQGIR---------------------PPMAGCNSSVGGMSMSPNQGLQMPSSRAYGLADPSTTGQMSGARYGGSSNIASLTPGPGMQSPSSYQNN-------------------------------------------------NYGLNMSSPPHGSPGLAPNQQNIMISPRNRGSPKIAS-------------HQFSPVAGVHSPMA------SSGNTG---NHSFSSSSLSALQAISEG----------------VGTSLLS-----TLSSPGPKLDNSPNMNITQPS--------KVSNQDSKSPLGFYCDQNPVESSMCQSNSRDHLSDKESKESSVEGAENQRGPLESKG----------------HKKLLQLLTCSSDDR-------GHSSLTN--------SPLDSS------CKESSVSVTSPS--GVSSS------------TSGGVSSTSNMHG----SLLQEKHRILHKLLQNG---------NSPAEVAKITAEATGKDTSSITSCGDGN------------------VVKQEQLSPKK-KENNALLRYLLDRDDPSDALSKELQPQVEGVDNK--MSQCTSSTIPSSSQEKDPKIKTETSEEGSGDLDN-----LDAILGDLTSSD---FYNNSISSNGSHLGTKQQVFQGTNSLGLKSSQSVQSIRPPYNRAVSLDSPVSVGSSPPVKNISAFPMLPKQPMLGGNPRMMDSQENYGSSMGGPNRNVTVTQTPSSGDWGLPNSKAGRMEPMNSNSMGRPGGDYNTSLPRPALGGSIPTLPLRSNSIPGARPVLQ---------------------QQQQMLQMRPGEIPMGMGANPYGQAAASNQLG--SWPDGMLSMEQVSHGTQNRPLLRNSLDDLVGPPSNLEGQSDERALLDQLHTLLSNTDATGLEEIDR-ALGIPELVNQGQALE--PKQDAFQ----GQEAAVMMDQKA--GLYGQTYPAQGPP-MQGGFH-------------LQGQS-PSFNSMMNQMNQQGNFPLQG----MHPRANIMRPRTNTPKQLRMQLQQRLQGQ-----------------------QFLNQSRQALELKMENPTAGGAAVMRPMMQPQVSSQQGFLNAQMVAQRSRELLSHH--FRQQRVAMMMQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTQAFSPPPNVTASPSMDGLLAGPTMPQAPPQQFPYQPNYGMGQQPDPAFG-RVSSPPNAMMSSRMGPSQN-PMMQHPQAASIYQSSEMKGWPSGNLARNSS-----------FSQQQFAHQGNPAVYSMVHMNGSSGHMGQMNMNPMPMSGMPMGPDQKYC---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QDK0-1", "uniprot_id": "A0A8M9QDK0_DANRE", "id": "A0A8M9QDK0-1", "name": "Nuclear receptor coactivator 3", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSGVGENSLEPLCSDRKRKLSTCDTP----GQG----CDKRRREQESKYIEELAELISANLSDIDSFNVKPDKCAILKETVRQIRQIKEQGKS---------------------------------------------SCGDDDVQKADVSSTGQGVIDKDHLG-------------PLLLQALDGFLFVVSREGSIVFVSDNVTQYLQYKQEELINTSIYNILHEEDREELHKNL---------PKSNGPNSVSWGGDSS---------------------------------------RQKSHTFNCRMLVKFGHGGPGGEEGAGGP--RYETMQ--CFALTQPKAMMEEGEDLQSCMICVARR--------VTA-----VERTERFSTRHELSGKLIEIEQQSLLHTTMRPGWEDLVRRCMQMFLHRSEGQPWSYKRHYHEAYVHGRAETP-----------PYRFSLSDG-TPVTAQTRSELCRNPVTSDPHTFLSTHLLQREQNGYRPN----QGGVM---------------------RSVMGN--------ANPNAQMGMGNTRGYGMNEQGHMGPRGGAMYGPGNRMNQMNPMHQMNQMNQMNSMNQMNMNQMNCMNQMGSMNQMNQMNQMNSMNQMGHPGMNQHQQGQFHGGGGYGMVMTSPSQGSPGMNPGQQNLMGSPRIRGSPKMGA-------------SPFSP-GGMHSPMGPVGMGGSSGSSGPSVGNTFSSSSLNALQAISEG----------------VGSSLPS-----ALNSPAHKSDSSPNINSTQSSQQGPIGNNKPITSDSKSPSSAHSTGLDQQQASSTENTDKP--DSQSNKDGSAGGEVNRRVPDGKG----------------HKKLLQLLTSPTEEI-------GIGTATSGPVPGRASTPMGSD------PKETGSGMMSPSSTGVSSSSGSSSGNNVNQQSSGGVSSTACPSGHHSTHTLQEKHKILHKLLQNG---------NTPDDVARITAEATGKSSLSSEHPGAEGRN---------------LELKQEQHSPKEGKKPQALLHYLLNKDDSKEPGATEVKPKLEELEARGASGGQGAGVTTSSSSNQESKVKLE----QPDELES-----LESILGGLRNPGPGMFVDS--GSGGSEVGNKQGNGPNSTAHDREGVGMGSGQRVPFQRAVSVDGKPMSGPGMTGR-KSAPSSLVKQEHTDSQIGMGGPNR----LMGMPNR----PPMAGAGDW--MSSSGSPAGSVGHPGMGRPGMDHN---PKSMMGG---PMVSRSNSVPATRSMLQ-------------------------QQLMEMGPYDVGMGMNSFRGQAPPPQSP--SWPDSGMGMEGPP--SANRLPINSPLDELLAPPSTSEGQSDERALLDQLDSLLNNTDVIALEEIDR-ALGIPDLINQGHSSDQPPPSDPFSGPCLGPDSSMGMEPPK--AMYGQGYPGPPSMGMQGGYGPGPNPGAGPGPGPMQGQSGPGFNPMMSQMNQQGGFPGMGGMGPMHPRANMMRNRVPQAKPLRLQLQQRLQGQ-----------------------QFLNQSRQAMGMRPDASPAG-NPGMRPSMQPGMGGQPGFLNAQMMAQRSREMLNLQTEMRRQRMMMMMQQQQQQQQQ------------------VAAGGFSPPPNVTAPTGMDNPMAGPPMSQPGQQAFNYGGNYGIGQQGDPSFVGTGSSPPNNMMSGRMGGPQNPMMQQHPQSNPMYQSAEMKGWGQGPMPMNNHPETVMKMCEYNFIPPATAISPAGGARTVWWNDDERLHAGGCEWQRCRTDAPNAGPDGHEHHGHGTHANGT-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9ND53-1", "uniprot_id": "M9ND53_DROME", "id": "M9ND53-1", "name": "", "aln": "MSIAAAENAGLSPSDLPDHWASGTSNPSTSTSSSSSSSISASGSNNNKYNSGNISVCNLPRSSPAAATAAVTLSSAAGGIGSNLLSGLHHGLAPGTHPLQRATAASGGGAGAGGVAGASTAAALTLQQHQHQQQQQQQQQQAQHQHQHQHQQQTQQQQLAYQHQQLQQQIISHRSIQNKAAATAAAQTANLAAALQRSAAIMNAVASPISANSANSATSGRKIRRKTDSKVNLPQSQINKCNNEKRRREAENGYIEQLSEILTLNK-RGDMTSTKPDKAAILNQVVRTYREICDKGQNRDISSTSTNNNNSTTTTNNNTNSNNNNNTSKPQATSTRCSRCATDNCSIHPVQQGEVSSTEPPLPEPSLLLGQVPEISAYFEALEHYISGVGWVLLQVNANGIIESCTQNIRDLIGYEKQELYHQPLYMYLYSGDHAKLEPIINTMYNNPNGGNSNSANNSGPGGSSAGTSAGVWGDLEELNNGNASQGSNSSGAGGLGGAGGAAAGKKRSISTKVRMLVKDTRTATQTSSNCEEKPLRQSGHQDKYEEVVLIAAPVKDDADASSSVLCLITRPEDESPLEINIQQHVQQQPIEQMTFKLDIHGKILTLDPT-ALREPFKQHLQTWVGRLWQDLCHPHDLS--TLKSHLRDIQDSASANSPGAGAGTSVVSRPFRLRLGAPDVYVHVKANSRLFLNQTPGEGDFIMSVQTLLNSENDMNSSNTGAGSGGLGLGQLCAMAPSPSLASSLLSSLSMDGLHGGTGSGSSSSPAASGMLPTHLLGGLVGGGQQGGGGNSTQTTSVGGPLMSSAIINGTGLQQQQQQQQRSGASSSASSSANALVNAFTASPAPAEHSFYGSDTFEFDIAAHSSSFELDPSGGVGAWTDSRPNSRASVATPVSTPRPPSGHGFSPAVCASPATPYQLSSHSAASLPSPQSNASAGGGNYGGFNFHSFDSSDVKPEKDVQQQQNQQQSNNNSSSSNPLLGGGLPNGVGGMLLSQQQQQQQTPPQQQQQQQQQESSERLRHLLTKSQSMAGGLGGLGDDEKYFKPEGSEEEKHASGGFKMGGQPGGMGMFGPMGSMGRGVGNSSMLHKAGNSQNPMLLKLLNEKSEDDDGNGSGGGPGSMNNSRQSELMRQLKNPDGGSHGMHRNSASGNMSTEDLKAMLKIQSDPSLNRKRSLNEPDDDPSAKRSEDKPSKLCTQNKMLAKLLQNPPKIPKAPNPEQPLQVKTLPDITSSTVSSTLAAPGNLISAGSTGPKAAANRNRKQQQQQQQQQQQQQQQQVAGIPSQQQQQQPNDVYLSQQQQQQLQSPQLAFQHQQLATTATTSITTAASTSAAAAAAAAILGEGDSELSKLLDSVMEYYPDDTPIVTNAPSEASAINDIQKSLMLDVESAAFGNDLNQQLMMTQQQQHQQQQQQQQLLALQLAQQQQQQRQQHLQQPPAYPGMLNMQQQQHQQQQQQNQQHIMQRLEAMRNQGNQGFQRPP-PMYPARGRGPMNAVATPGGVVLPAQQQLRNIRQQQQLAAAQQKERLLQQQQKQQLLVPENASEYWGNSNLQLIIKLIVSYILAGMNAGLNNIGSLLNTTGAPNVSLSRTNLPSDAQLSPNFAQTLMQQQLSPGRSAPYSPQPNQGYAPQFPQPGQRLSPQQQQQLSQQQQNNVQQQQLAYQQQQVGDGGRSNTPFGSNSGMQSPGMQNSPQQWGSGGGGGGGPGGPLPSGNAG------------RTLQQHNPMLIAQLQGVSPYNARQYQQNQRRGLNSPGAVGPGGNPAAQAALQRQNSFQGQGGGGATTPDGSGVGFGGPQSPYGTNVNVFQQQQLQRLQRQGSVPQATQHLPGSPRFGSSPGSSNNTDSSAAAGNQQQQQQQQQQQQQQHQQQQHQQLMNG------------------LSMSPHPHPHPAMMGVGGMGSGGGNGIIGLGGGGGNYGATLGGYGQSQQANDFYGRAQTAGGGGSVAGGNANSEFVKQELRAVVSVRAQQAAAAATGGAGVGGGVAQRGQTPQSPLQQGSVIGGGGGIVGGVNSTNTMGNVTPTGSGNVSNSMLNTPPDPTLSFSFETPDFFTSSATR", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * * : : . : * * :: . *::* :*: *. . * .::.*.* * ...: . ::*.: * ..:*. ... * . * .. * :: * . .* . : . :: . :. .: : :. . .. *..: : :* * . :*. .. * .*. * ::*.**.:.. : :.: :* .* . *.. : :..*: : * . : .... . . : . . : .. . . * : **:**. ::: * .: .. ... :::. . *.. . . . ...: . * ::::* ***** : * :* :. ::.. : : * *:* . : :: .: ::: . : : : : : : . .* ... .: :. *:::: . : .. . . : . : :: . : : . * : . * :. . : . *: . . :. . . * : * : :. * . . * . : : : :.. *. ..* . : :.. . : * *. : *.: :: : :* * : .: * ::. : . * . .*. * * : . : :. . .. : . :* *: :*** :* :* : : . . : . * : : . : ::*: .* * .. * . . . .* : * . * : : : . .. * * : :: : :: . . . . . . : . ** ", "identical_positions": 94, "similar_positions": 308, "identity": "4.51%" }, { "cls_id": "homologset.agr.MGI:1276539", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZSP7-1", "uniprot_id": "TTC3_RAT", "id": "D3ZSP7-1", "name": "E3 ubiquitin-protein ligase TTC3", "aln": "MPGHRGAPHLPPWVCGLCSMDDFAEGGLSLADDILLEDYPYEDDCICTPDFTTDDYVRVTQLYYEGVGMQYKDYAQSEKNLEYDICNIWCSKPLSILQDYCDAIKLYIFWPLLFQHQHSSIISRLHPCVEAIRSR--AAEISLKKLQHLELMEDIVDLAKK---VANDSFLIEGLLKIGYKIENKILAMEDALNWIKYTGDVTI---LPKLGSVDSGWPMLSIFFTEYKYHITRVVTENCNLLEEFRRHSCMQCVKQGELMKMRGNEEFAKEKFEIAVIYYTRAIEYRPENHLLYGNRALCFLRMGQFRNALSDGKRAIVLKNTWPKGHYRYCDALSMLGEYDWALQANIKAQKLCKNDPEGIKDLIQQHIKLQKQIEDLQGRTSNR-NPIKAFYESRAYIPRNSSAPAFRTSLNFVETERGFRKTKYRMANGGGHQNQKVADEALKGDDCDCHPEFLPPPSQPPRHKGKQKSRNNESEKPSSNSQVTLQVDLKSILEKQFSKSSRAAHQDFANIMKMLRSLIQDGYTALLEQRCRSAAQAFTELLNGLDPQKIKQLNLAMINYVLVVYGLAVSLLGIGRPEELSEAENQFKRIIEHYPNEGLDCLAYCGIGKVYLKKNRFLEALNHFEKAKTLICR--LPGILTWPTSNVIIEESKPEKVKVMLEKFVEECKFPPVPDAVCCYQKCRGFSKIQIYLTDPDFKGFIRISCCQYCKVEFHMNCWKKLKTTTFNDKIDKDFLQGICLTPDCEGIISKIIIFSSGGQVKCEFEHKVVKEKAPSRPVLKQKCSSLEKLRLKEDKKLKRKIQKQEAKKLAQERMEEDLRESNPPKPEEPEETVESAQSCQFLDDRILQCIKQNADKIKSVVLNTSTLLKELLSWKVLSTEDYTTCFSSKNFVHEAVDYVIGHLIQEKNRVKTRIFLHVLSELKELDPKLAPWIQRLNSFGLDATGPFFTRYGASLKELDFN--IVTFLWSEKYGHKLGSIEGKQ------LDYFCEPASVMEARCLIWLLEEHRDKFPALHSALDEFFDIMDSRCTVLRKQDSDEMPFGCIKVKNKGKKKKPKDSKPMLVGSGTASVTP---SSETVTP-EDHNRRNSDSAGPFAVPDHLRQDVEEFEALYDQHSSEYVVRNKKLWDINPKQKCSTLYDYFSQLLEEHGPLDMSDRMFSEEYEFFPEETRQILEKAGGLKSFLLGCPRFVVIDNCIALKKVASRLKKKRKKKNIKTKVEEISKTGEYLRVKLPLNPTAREFQPDVKSEAAA--------EDVTSIPGPADSSAPAAEDLKPQLDSDSSSGSASEDSRLEVVSPDLPTPLCEDAS------PSPTPAPEDAKPTYWTQSHLVTGFCTYLPFQGFGIAQSRPAYINMVPSLSQFTSIYTPLANISSEYPMPRSMPVVPSFVASERADGNAAAYFESHRLNTENASDDHTASETQILEGPLGMCVKSQSSTADARTALSEPEGNSRHSGSSDSLWEASLENVSGITDVPPAPSVAIQVSRSLIHQEVNTEPYAPFERQQGDLSQKEKECHLLREQLQVACEECEQMELRSSQETRDLEEKLQRHAEENKVSLPELQWALGKLDREIKKWHQEKKEIQERLKALKKKIKKVINTSDMSAQKNDGLDKECESQPDQSLGISSALTDEKAKVEESVRKGKELYEESQQRAVAAEVSVLENWKEREVCKLQGVATQAEACLKSLKLMNSDSAAYPDVECDILSWETFLSTVTEEIENTKCQFEEQIKAIKSGSRLSDLSSVQVSELLFPACSMIHPQLLSESSRHEDHGLVACVDSMTG---AVLNDPYVGPDSGCSEEVP-ELSLGSPTHHPEGAQQLEVKKASQVSPSEQNPEADEK---PSGQATRSSQSQKNPFNSIIEHLSVIFPCYASSELSGFIKKVRNKSKN-SFSGLSIEEIVERVTEHIVEEQK---KKKPNPGKDKKTSEAHPAASVSKSSPSPPLAAAGPSAKTKGQKKDDVP---APDGNSCQICHEIFKSKNMRVLKCGHKFHKGCFKQWLKGQSTCPTCGSSDLLSEE--------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88196-1", "uniprot_id": "TTC3_MOUSE", "id": "O88196-1", "name": "E3 ubiquitin-protein ligase TTC3", "aln": "-------------------MDDFAEGGLSLADDILLEDYPYEDDCICTPDFTTDDYVRVTQLYYEGVGMQYKDYAQSEKNLEYDICNIWCSKPLSILQDYCDAIKLYIFWPLLFQHQHSSIISRLHPCVEAIRSR--AAEISLKKLQHLELMEDIVDLAKK---VANDSFLIEGLLKIGYKIENKILAMEDALNWIKYTGDVTI---LPKLGSVDNCWPMLSIFFTEYKYHITRVVTENCNLLEEFRRHSCMQCVKQGELMKMRGNEEFSKEKFEIAVIYYTRAIEYRPENHLLYGNRALCFLRMGQFRNALSDGKRAIVLKNTWPKGHYRYCDALCMLGEYDWALQANIKAQKLCKNDPEGIKDLIQQHVKLQKQIEDLQGRTSNK-NPIKAFYESRAYIPRNSSAPAFRTSLNFVETERGFRKTKYKMANGG-DQNQKVADEALKGDDCDCHPEFLPPPSQPPRHKGKQKSRNNESEKPSFNSEVSLQVDLKSILEKQFSKSSRAAHQDFANIMKMLRSLIQDGYTALLEQRCRSAAQAFTELLNGLDPQKIKQLNLAMINYVLVVYGLAVSLLGIGRPEELSEAENQFKRIIEHYPNEGLDCLAYCGIGKVYLKKNRFLEALNHFEKAKTLISR--LPGILTWPTSNVIIEESKPEKVKVMLEKFVEECKFPPVPDAVCCYQKCRGYSKIQIYLTDPDFKGFIRISCCQYCKVEFHMNCWKKLKTTTFNDKIDKDFLQGICLTPDCEGIISKIIIYSSGGQVKCEFEHKVIKEKVPSRPVLKQKCSSLEKLRLKEDKKLKRKIQKQEAKKLAQERMEEDLRESNPPKNEEPEETSDSAQRCQFLDDRILQCIKQNADKIKSVVLNTSTLLKELLSWKVLSTEDYTTCFSSKNFVHEAVDYVIGHLIQEKNRVKTRIFLHVLSELKELDPKLAPWIQRLNSFGLDAIGPFFTRYGASLKELDFH--VVTVLWDEKYGHKLGSIEGKQ------LDYFFEPASAMEARCLIWLLEEHRDKFPALHSALDEFFDIMDSRCTVLRKQDSDEMPFGCIKVKNKGKKKKPKDSKPMLVGSGAASVAP---SSEAVTP-EDHSRRNSDSAGPFAVPDHLRQDVEEFEALYDQHSSEYVVRNKKLWDINPKQKCSTLYDYFSQLLEEHGPLDMSDRMFSEEYEFFPEETRQILEKAGGLKSFLLGCPRFVVIDNCIALKKVASRLKKKRKKKNMKAKVEDISKTGEYLRVKLPLNPTAREFQPDVKSEALS--------EDVKSIPGPADSSTLAAEDLKAQLDSDSSSGSASEDSRLEVASPDSPTPLCEDAS------PSPTPAPEEAKPTYWAQSHLVTGFCTYLPFQGFGITQ-RPAYINMVPSLSQFTSIYTPLANISSEYPMQRSMPVVPSFVASNRADENAAAYFESPNLNTEHDSGDHMASETQILEDTLGVCVRSQGSAADADPALSEPEGNSEHSGSSDSLWEASLENVSGTTDAPAAPSVAIQVSRSMVHQEVNTEPYEPFETQQGDLSQKEKECHLLREQLKVACENCEQIELRSSQEIKDLEEKLQRHTEENKISKTELDWFLQDLDREIKKWQQEKKEIQERLKALKKKIKKVINTSEMSAQKNDGFDKECEPHPDQSLGFSSALTDEKTKAEESVRKGKELYEESHQRAVAAEVSVLENWKEREVCKLQGVASQSEAYLKSLKLMSSDSATYPDVEYDILSWESFLSTVREEIESKKSQFEEHIKAIKNGSRLSDLSSVQLSEVSFPGCSTIHPQFLSESSGHEDPGLVACVDSMTG---AVLNDPYMDSASGCPEEVP-ELSLGSPTHQPEVTQQLELKGASQVSPSEQSPEADEK---LSGQATRSSQSPKKPSNSIIEHLSVIFPCYTSTELAGFIKKVRNKTKN-SFSGLTIEEIVEKVTEHIVDEQK---KKKPNPGKDKKTSEAHSAASVAKSSQSPPLAAAGPSARTKGQKKDDVP---APDGNSCEICHEIFKSKNMRVLKCGHKFHKGCFKQWLKGQSTCPTCGSSDLLSEE--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P53804-1", "uniprot_id": "TTC3_HUMAN", "id": "P53804-1", "name": "E3 ubiquitin-protein ligase TTC3", "aln": "-------------------MDNFAEGDFTVADYALLEDCPHVDDCVFAAEFMSNDYVRVTQLYCDGVGVQYKDYIQSERNLEFDICSIWCSKPISVLQDYCDAIKINIFWPLLFQHQNSSVISRLHPCVDANNSR--ASEINLKKLQHLELMEDIVDLAKK---VANDSFLIGGLLRIGCKIENKILAMEEALNWIKYAGDVTI---LTKLGSIDNCWPMLSIFFTEYKYHITKIVMEDCNLLEELKTQSCMDCIEEGELMKMKGNEEFSKERFDIAIIYYTRAIEYRPENYLLYGNRALCFLRTGQFRNALGDGKRATILKNTWPKGHYRYCDALSMLGEYDWALQANIKAQKLCKNDPEGIKDLIQQHVKLQKQIEDLQGRTANK-DPIKAFYENRAYTPRSLSAPIFTTSLNFVEKERDFRKINHEMANGG-NQNLKVADEALKVDDCDCHPEFSPPSSQPPKHKGKQKSRNNESEKFSSSSPLTLPADLKNILEKQFSKSSRAAHQDFANIMKMLRSLIQDGYMALLEQRCRSAAQAFTELLNGLDPQKIKQLNLAMINYVLVVYGLAISLLGIGQPEELSEAENQFKRIIEHYPSEGLDCLAYCGIGKVYLKKNRFLEALNHFEKARTLIYR--LPGVLTWPTSNVIIEESQPQKIKMLLEKFVEECKFPPVPDAICCYQKCHGYSKIQIYITDPDFKGFIRISCCQYCKIEFHMNCWKKLKTTTFNDKIDKDFLQGICLTPDCEGVISKIIIFSSGGEVKCEFEHKVIKEKVPPRPILKQKCSSLEKLRLKEDKKLKRKIQKKEAKKLAQERMEEDLRESNPPKNEEQKETVDNVQRCQFLDDRILQCIKQYADKIKSGIQNTAMLLKELLSWKVLSTEDYTTCFSSRNFLNEAVDYVIRHLIQENNRVKTRIFLHVLSELKEVEPKLAAWIQKLNSFGLDATGTFFSRYGASLKLLDFS--IMTFLWNEKYGHKLDSIEGKQ------LDYFSEPASLKEARCLIWLLEEHRDKFPALHSALDEFFDIMDSRCTVLRKQDSGEAPFSSTKVKNKSKKKKPKDSKPMLVGSGTTSVTS---NNEIITSSEDHSNRNSDSAGPFAVPDHLRQDVEEFEALYDQHSNEYVVRNKKLWDMNPKQKCSTLYDYFSQFLEEHGPLDMSNKMFSAEYEFFPEETRQILEKAGGLKPFLLGCPRFVVIDNCIALKKVASRLKKKRKKKNIKTKVEEISKAGEYVRVKLQLNPAAREFKPDVKSKPVSDSSSAPAFENVKPKPVSANSPKPACEDVKAKPVSDNSSRQVSEDGQPKGVSSNSPKPGSEDANYKRVSCNSPKPVLEDVKPTYWAQSHLVTGYCTYLPFQRFDITQTPPAYINVLPGLPQYTSIYTPLASLSPEYQLPRSVPVVPSFVANDRADKNAAAYFEGHHLNAENVAGHQIASETQILEGSLGISVKSHCSTGDAHTVLSESNRNDEHCGNSNNKCEVIPESTSAVTNIPHVQMVAIQVSWNIIHQEVNTEPYNPFEERQGEISRIEKEHQVLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRHLEENKISKTELDWFLQDLEREIKKWQQEKKEIQERLKSLKKKIKKVSNASEMYTQKNDGKEKEHELHLDQSLEISNTLTNEKMKIEEYIKKGKEDYEESHQRAVAAEVSVLENWKESEVYKLQIMESQAEAFLKKLGLISRDPAAYPDMESDIRSWELFLSNVTKEIEKAKSQFEEQIKAIKNGSRLSELSKVQISELSFPACNTVHPELLPESSGDDGQGLVTSASDVTGNHAALHRDPSVFSAGDSPGEAPSALLPGPPPGQPEATQLTGPKRAGQAALSERSPVADRKQPVPPGRAARSSQSPKKPFNSIIEHLSVVFPCYNSTELAGFIKKVRSKNKN-SLSGLSIDEIVQRVTEHILDEQK---KKKPNPGKDKRTYEPSSATPVTRSSQGSPSVVVAPSPKTKGQKAEDVPVRIALGASSCEICHEVFKSKNVRVLKCGHKYHKGCFKQWLKGQSACPACQGRDLLTEESPSGRGWPSQNQELPSCSSR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3BCR2-1", "uniprot_id": "A0A8M3BCR2_DANRE", "id": "A0A8M3BCR2-1", "name": "RING-type E3 ubiquitin transferase", "aln": "---------------------------MSDSDDSDLEEG---------PNVQRHKTKIVYHAQFPYIHMEPPDIVYER----------WCKMKLKRKQDLGHLMHVSVFWWHILLRQQENHPTTAWAVKMGFLDSNVSNDLSLKRLEKMEILESILATMERGLSLRDVENKARAVVSLSQRFFQEEDCLTEAIRWLLDSGDPDLGQKLMDLGSVEVRYLTLSFVFMEYARYIQVVSCSKKKALMEMKFEPDSWSLSKSDEMKNKGNEHFQKKKYDVALKWYSKAIKYHPNNHILYGNRALCLLRSGKYLKALGDGKRAIVLQPDWAKGHYRFCDALFYLGEHQRALLANQQAQDACRADVEGQKDLLQQHERFQSELQEARDMKTKKPDPKKVSSKARSHTAGASSAAHLKTSAPPETPPEPQTKKSEKQKQQADTSGPSGARAHTDGG-----ADRLRDVSSESSPRKAKKASSSTAEKPAVRSKLPAAADRASAPAEVVS---------AAAVRERFCAAVLEAHVALSDQRCHNAQQSFSVALAILESSSTTELGLTELDKSVLLYGYATALLETGQPEELAEAEKLFAKLESTER--KFQSLVHYGMGRVYLKENRFAKARECFSNALLMIQRHITPGKLTWPTTKAIVEETQPAWLQEHLESLVEVCRFPPKADAVCRHQQCVSHS-VQIYFSDPDFKGFIQLVCCQSCRIEFHMSCWRKLKTLSFADKNDKDFLKDSCFTPDCAGQICHILIFGSTGLIKCEFKSSIPKARAAGRSRLRQQCTSIKKLMSKNDRKLRRKQQRLAARSSHQEKREVMREEAAKEQPADRASPRD-----CIYMDRVLQQIHDNKALFKEEPVSISCFWEHLRPWLDLFESKGQESVLNSRRGVGVLSELVDLLLESRNRVWARVFIQTLGSTLHIKPRLQHWAQQLDDTGLKAAQSFINRYRSHLEDLELKPLLSFPPLQESLVEKLGSVTELFDRDDFTVMEYLRQAPAKEMRLFIWTLESSRERYQSCHTILDQYFED-DAVCLVIKKTDDDEHMSSVFKSKNRHRKKKHKELKSVIVLSGMRAGHSRDEDDEDELFSEEDSLMFLNDMDPFSVPDHLRYQLAEFEENYSGSAQRSYYER--MLDNHPDPTKETLYDYFAQVLEEHGPLCATDPLLVGELQNFPLEAQQQIADAGGLQAFLLQSLRFTMTERLIGLMKHAVCLSESSN------------------THSQILNPSASEFWP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSGEPPSSTGEPALLLPDPYTDEEDQLSAAEMTESDTEETRAEKHT----AVRAQDFQDRTDVSVNTEPCAPFENNSGELMGLQKRRLYLLEELQRIRADGEAEQQRRQEELTELQEDTHNISQRMQIASTELSMFQQKLEEEVKKDQQEKKENQETLRSLKMEIKELVELQESLSRDISVRNRQYEAELELFLDVSNQCAAERLSLEDEIKRFRDACVKAERRSASAQLCVLQSRREHALRRLRMTVSEGKMVVKHLSDVALS-SPSAALLSAIEDWKRHVSEAEGRIHATEEECEAQMQAVQQGSRLCSLPDISTPSVPSAPALPALQTPVSSAAPEE-----------------------------------------------------------------------------SSSRRSAAPQHLSVYERIVERLHIMFPHYDRLVLNKFLQEVRSSCSGGVLSSLTYNEVINRVAQLILDHQENICQQMNITAGDAADLSCPPSDCTLRAAGTPPLTHVWKNVPEKHRNSALVLN----MEDPCIICHEDMSAEDLCVLECRHSFHRECIKSWLKEQSTCPTCREHALLPEDFPLLPGRQRRTHTAS-----", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: :* **: .:. .. * : : :: * .. **. :. ** . ::: :** :: :*:.. : . . . : ::.**:*:::*::*.*: :: : : . .:: :. :: :: .: :*:.*: :** : * .***:: : **:.* ** :* : .. : * *:: .. .:.:.: ** :***.* *:::::*: :*::**:*:*:*::********:** *:: :**.***** :*: *.*****:**** ***:: ** ** :**. *: * ** ***:*** ::*.:::: :. .::: :* *. : *:: . **. : ** . * . . : . .. . * . . .: *. . : :*: .. :** : * :. .* . : .* * : : : : : :.: ** :***:.* *:*: * *:... .:*.*: :: :::** * :** *:****:***: * :: . ::.*.: *:*:****:*** :* : *.:* :* * ** *****::.*:**::* :: **.:** *:*** .**:* :*:* ..* :***::********:: *** *::****.**:**** :* ** *****:. *:**** * *.:*:*:.* * :****: .: * :.. *. *:*:*:*::** *:*:**:** *: *:. **: * .*: : : .. : : **:** *:: :*. . : : :.* .* * .. .. . . .:. :: *::..*** :*:*::.*.. .:.*:* * *:*:. **.* .*:.** : *: *:: : .*. .**.*: : : . *. * * :** **. *::: : *: **::*: *: * *::* *..* . * **: :*** *: *.::* ** : . ..* *:.. :. .**:****** :: *** *. :.. .. : * :*. . .******:*.******* :: :: * : ** *::* : .****:.*** . **.: :. *.* * * *.:. : . ***:* ** * :. .. *:.:. *.:. :... .: . * *.. . .. * * . . .***** *** ..*:: :*. * ::*: : * : : :* :*:*. :. :. ::: .**. .*:.*:** :***** ** *::** :**:: : .: ::. . ::: * . : * .*. : *: . *: ::: :: ::.:*:.:*::.**:. :* : :*: ::.: :* * : . :. . : * .*: .:* . .*. : : * :::*::.****..*..:. ..: . . :..:: .: .. :: . . : *:*:* ::** * * *:::**.. .. :*.*: :*::::*:: *::.*: :: .. * . .: . ::: .* . . . * :: * ..* **** :.:::: **:* *.:*: *:*.*** **:**:* **.*: ", "identical_positions": 473, "similar_positions": 616, "identity": "22.84%" }, { "cls_id": "homologset.agr.MGI:1276545", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8M9PJB1-1", "uniprot_id": "A0A8M9PJB1_DANRE", "id": "A0A8M9PJB1-1", "name": "Histone-lysine N-methyltransferase, H3 lysine-36 specific", "aln": "---------------------------------------------------------------------------------------------------------------MDAGLSDICTS--------------PPSPDFSLDSSSPFANG-LHFESILFED----EEEDEVMDPEP---VSQPERNLCGSTSDCTTNTNLKTNLDGKSRRKNSKAHSS------------LEQDVVFQDKAKSDS------------------------------GLSTLVSRPGGV--------LMKQKKKSKTKALPP---------VKYLEGEVIWAKFNRRPWWPCQVIIHPLEGVYHKMKEPPDRTTRQYFLKTFGEPEEQAWVPERSTHIFVGGYQFNNLPFVKGSGHQRDENTRHSIPKRFLNSWSASVVAAEALLLE----KPRVTSPSSAFKTISEETIN--NTEIKVSVPVDLPNSSFLINGA-VIQNNHLNSLPHNRKSKNKKKPTISHCRISEELNCEKG------------MIMDALDSPYSDIDSVPQIRRFPKSNEQISNHYVINYKQSSATPTVLPSTNDKDVKKNVENQGGLWFSKTGKGQVN-----------GISRAGIKSVNCSFGKVSCKIKMPDSASMKPKDNHNTGLEHLSTEAKKALDRRVKCLPASSR-------LMTRALKAMEDAEWTKESSSDLETKNCVSSFDSPSLETSDV------------------HNSILLQKMPTAAIHDLKEDSKISTHAKLSSELLCCKDDEHSVKSEDESSLVSQAPCAFHSSTRKQNSHVNDLSSSPTPSLHLN---------------------------LKDMDNMNEISFKSLANEHSGQPLS----------------FHPDSNYKFSTFLMMLKDMHDSREKDGNVLVVEPLP-----------------------------------------------------TTELINEEPLLISDVKD------------EKATSKQKKVKPKT-NVMSENHLASTISKTAQRSSKKIS----------------------------------------------------------LKKKTTDIKANIDYKSFDKLISAHR-------LTSKEAETNFSANVPKKRWQKFDQVSEK-------------------------TVHIVEGNCIHKTERVSSENCDVSMDGTNKSCFFGPETTSNALECN------------------QGNCQNTEAPTECKRIRKPSKRLIEWTEEYDQLFSAKKKAKKKPDSVTKIENQKCSEPVAKTYDEVKQKPQVTEQDVSRRLPELQTPPPEDQSQSTPLINTLPCQESQVLSAETLTPPPEIIPSPCDNISNRDQLQRQNPVAVGDSVCLNSKRQRKPTKKILESSIEAEPILIPKRKMKSMKICSSGHSTNSGVEQQSSKSKNKLSIESSDPPSD-PMLKSTEMEIDVSPAVLQTINTESADDGSDTLRCSGSQMTE------SSEFYSEREENSQSDKVLLDSRRLSEEKGGSTSVKENVCPMCEKQGDLLLCEGQCCGAFHPQCTGLNEPPTGKFLCQECTSGVHSCFACKRLGEDVRRCMVPGCGKFYHGECAASHAPTVPLNRAFRCPLHACLSCFILNPAN--PSVAKGQLTRCIRCPVAYHSSDFCIPAGSVTLTDSNIVCPNHFTPRKGCRNHEHVNVSWCFVCSEGGSLLCCESCPAAFHRECLNIDMPE-GSWYCNDCRAGKKPHYKEVVWVKVGRYRWWPAEVSNPKDIPENILRMKHDVGEFPVLFFGSNDYLWTYQARVFPYMEGDANSKEKMGKGVDSTYKKALDEAALRFKELQAEKELRQLQEDRRNDKKPPPYKQIKVNKPFGKVLIISADLSEIPRCNCKATDENPCGMDSECINRMLLYECHPQVCPAGERCQNQCFIKRQYCQVETFRTLSRGWGLRCVHDIKKGGFISEYVGEVIDEEECRARIKHAQENNIGNFYMLTLDKDRIIDAGPKGNEARFMNHCCQPNCETQKWTVNGDTRVGLFSLTDIPAGTELTFNYNLECLGN-GKTVCKCGASNCSGFLGVRPKNNPPS-DDKGRKLKK----KRKSQQEVIKEREDECFSCGDGGQIVSCKRPGCPKVYHADCLNLTKRPAGRWECPWHQCDLCGQEAASFCEMCPSSYCVEHRDGMLFISKLDGRLSCSEHDPCGPEPLEPGEIREYPGELRPTYPIN-----------------------------------------------------------IIKSAKNKSHILNTPKAVPQAPSPLDVAPQV---SPSPSCSPPPLT------------------------IFLNGPYSPNSSYEEKK-------------------------------------------EEEES---VTLLEKDGEKSVPRDKSER-------LRIKKKTEV----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0ACD6B642-1", "uniprot_id": "A0ACD6B642_DANRE", "id": "A0ACD6B642-1", "name": "Histone-lysine N-methyltransferase, H3 lysine-36 specific", "aln": "MNQSYKVAGRDGSECRGDPQDSRALDVRIGSCGQ-QSTKADQSSAMHFLNPGYKLSAPFAYNQRESTSNYSPLRRLQDLTTMVNHADGGLQDKDFHGRNKLLMHSPIGGNEFGIGLYNTTNSQGNTAIQDLDKNGFSPVSSDSLEHFSPISNGFLHFDSTLFDSGDSKDNDEDVKGEVA---TFKDTSKKCQKRNVAKTKTQSSHRLDANKHSSKNTAKSDPPASPFHVPFTMMEDFDSMDDYSDSDCDLP------------------STENCASIFNLSKRAHSPSDS--------HSNPSSSPKKKQLLS---------VKYSIGDVVWAKFNRRPWWPCHVTTDPQIDVHTKMKDPSRRPCRLYFVRMFGEIVDQAWVPAKATFPFEGGDQFEKLPVLRRRGRQKEKDYKYTVPKRLIPSWKASVLEAEASLTKQLNSEPPLTLIQDVCVPITEDKAHKKNPACPKSTTLSTPSSSLLSNGLNASVKNRLKPGTASKKKATKKMIQSQSIKLSETPSLFKSKSNPSSDK--PSIATDPLDSPYSDIDSVPRIL----CSKRIDESLQVELEKELSTKTTKVQACKKTSKNSVDKPG-------KKTDVK-----------CLK-------NSKLKKSTPKDKTLKATSSRLKESSSPG----SSDGSFAMHS--HYLPASSG-------LIVRALAAGEETKE-KDLSHEPNSHSPSSEHSSPTNHELSK------------------QNWEVKNKSESS---EESADASDSPPNPTSIKRIKKRPQKNGIHKDPPPKSHEES-----ESKVNNESMFSDTSSSSIPSPSISP--------------------------MDAFQDIKELSFRSLVKEECSSGESP---------------LRADSNYKFSTFLMLLKDLHDSREKEGKPLTLPPTS-----------------------------------------------------PSSLIKEEPSLIPVGEEPPNEVLCEKEFAEQSSLPGKTSTPNN-SKQSKAKLKSTVKKESQKPDIVIDS------------------------------------------------------VSPLKKPISPVGLDVLDKSLPLLGDLPKSSDVSAAVTDVCAKGTISKVAPKKRWKTFESELGK-------------------------SIK-------PKSDQVDSTLDEVKSVSTEPNGVF----KDGLQESA------------------HSDVPNKKDASENKRLRKPSKRLIECGEEYEQIFPSKKKTKKS------TESCKTGSCISNTTPEQPASDQITPDAVS--------------SSSAEKPLDHDVAEEQKPPADVLVPPSAPKSPSCATSLETEPCEKK-------SAPLERKRPRKSVHKVLDCAIEGESVKIPKKGESRQHKTNPEESGVRDLEKQEEAGPPPSSPCAVSAQSEGELRTSSPIQPDVPSVSQIPVEGEQSSPSKPQMNNEDSLISEGFGAGLNDSAFSSRDSLSG-DLSGLSTNKRSVERGGGASLKENVCQVCEKTGELLLCEGQCCGAFHLQCIGLTETPKGRFICQECKMGVHTCFVCKKPDKEVRRCMIPVCGKFYHMDCILKYSPTVAQNRGFRCSIHVCLSCYITNPNN--PGISKGRLTRCVRCPVAYHANDYCMAAGSVPLANNSFLCPNHFTPRKGCKNHEHINVSWCFVCSEGGSLLCCESCPAAFHRECLNIEMPQ-GSWFCNDCRAGKKPHYKDILWVKVGRYRWWPAEVTQPKSVPENISRMKHEVGEFPVHFFGSKDYVWTYQARCFPYMEGDANNKEKMGKGADAVYKKALNEAADRFRELLKEKEMRQLQEDRKNDKKPPPYKHIKVNKQIGKVLIITADLSEIPRCNCKATDENPCGIDSECINRMLLYECHSQVCPAGERCQNQSFTKRQYTEVEIFRTLSRGWGLRSISDIKKGAFVNEYVGEVIDEEECRSRIKNAQDNDICNFYMLTLDKDRIIDAGPKGNESRFMNHSCQPNCETQKWTVNGDTRVGLFALEDIPKGVELTFNYNLECLGN-GKTVCKCGAPNCSGFLGVRPKNQPPS-DDKTRKLRRKVSGKRKSQSEVTKEREDECFYCGDGGQIVSCKKPGCPKVYHADCLNLSKRPAGRWECPWHQCNECGREAASYCEMCPNSYCEQHREGMLFISKLDGKLSCSEHDPCGPDPLEPGEIREY------VPSTS-----------------------------------------------------------IVGQAPNMSASGRITQPALPPAAPLFIPAQN---RPAFQSQRDPYG------------------------DEVVDNILPSSSPKDIK-------------------------------------------EEDMSDGEVVFEEEEEDLELVDDEEDEEEIDCRGMGLEDEEEEEEEFEDYEDDFVNVDFVGTEDGDEVEGDEQETSWDELVEAEK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8I6AMN8-1", "uniprot_id": "A0A8I6AMN8_RAT", "id": "A0A8I6AMN8-1", "name": "Histone-lysine N-methyltransferase, H3 lysine-36 specific", "aln": "MDQSCELSRRNCLLSFSNSVNLDAPEDKDSPFGNGQSNFSEPLNGCTMQLPTAS-GTSQNAYGQDSPSCYIPLRRLQDLASMIN---VEYLSGSADGSESFQDPAKSDSRAQSPIVCTSLSPGGPTALAMNQEPTCNNPPELQLSVTKTTKNGFLHFDNFTCVDDADVDSEMDPEQPVTEDESIEEIFEETQTNASCNYEPKSENGVEMAMGSEQDSMPESRHGAVEQPFVPLAPQTEKQKNKQRSEVDGSNEKTALLPAPNSLGDTNVTIEEQFNSINLSFQDDPDSSTSTLGNMLELPGTSSPSTSQELPFCHPKKKSTPLKYEVGDLIWAKFKRRPWWPCRICSDPLINTHSKMKVANRRPYREYYVEAFGDPSEKAWVAGKAIVMFEGRHQFEELPVLRKRGKQKEKGYRHKVPQKILSKWEASVGLAEQCDVPR-GPKTQKCVPSSAKLDSEEDMPFEDCANDPDSEHDLLLNGCLKSLAFDSEHSADEKEKPCAKSRVRKSSDNIKRTSVKKGLMPFEAQKEERRGKSPENLGLDFLSGGVSDKQASNELSRIANSLTGSSAAPGQFLFSSCGQNTAKTDFETPNCDSLSGLSESALISKHSGEKKKLQPGQVCSSKVQLCYVGAGDEEKRSDSVSVCTTSDDGSSDLDPTEHNSEFHKSVLEVTDALDKTENALSMHKN-ETKYSRYPATN-RVKEKQKSLITNSHTDHLMDSTKTVEPGTAEISQVNLSDLKISSPIPKPQPEFRNDGLTTKFNAPPGIRNENSLTKGGLANQTLLPLKCRQPKFRSIKCKHKESPTAAETSATSEDLSLKCCSSDTNGSPMTSISKSGKGEGLKLLNNMHEKTRDSSDIETAVVKHVLSELKELSYRSLSEDVSDSGTSKSSKPLLFSSASSQNHIPIEPDYKFSTLLMMLKDMHDSKTKEQRLMTAQNVASYRTPDRGDCSSGSPVGTSKVLVLGGSTHNSEKPGDSTQDSVRLSPGGGDSALSGELSSSLSVLPSDKRDLPACGKIRSNCIPRRNCGRAKLSPKLRVTISTQMAKPSVNPKALKTERKRKLSRLPAVTLAANGLGNKESGGSVNGPLKGGAQDPAKEEPLQQMDLLRNE------ETHFDSKVKQSDPDKILEKEPSFENRKGPEVGSEINIENDEPHGVDQVVPKKRWQRLNQRRPKPGKRASRFREKENSEGAFGVLLPGDPVQKGRDDYLEQRAPPTSILEDSAADPNHVSHSESVGPRLNVCDKSSVSMGDLEKETGIPSLTPQTKIPEPAVRSEKKRLRKPSKWLLEYTEEYDQIFAPKKKQKKVQEQVHKVSSRCEDESLLARCRSSAQNKQVDENSLISTKEEPPVLEREAPFLEGPLVQSDLGVAHAELPQLTLSVPVAPEVSPRPTLESEELLVKT-------PGNYEGKRQRKPTKKLLE-SNDLDPGFMPKKGDLGLSRKCCESGHLENGVGDSRATPHLKEFGGGTTRIFDKPRKRKRQRHGTARVHYKRVKKEDSARETPSSAEGELMIHR-----TAASPKEILEEGIEHDPGMSASKRLQGERGGGAALKENVCQNCEKLGELLLCEAQCCGAFHLECLGLTEMPRGKFICNECRTGIHTCFVCKQSGEDVKRCLLPLCGKFYHEECVQKYPPTVVQNKGFRCPLHICITCHAANPAN--VSASKGRLMRCVRCPVAYHANDFCLAAGSKILASNSIICPNHFTPRRGCRNHEHVNVSWCFVCSEGGSLLCCDSCPAAFHRECLNIDIPE-GNWYCNDCKAGKKPHYREIVWVKVGRYRWWPAEICHPRAVPSNIDKMRHDVGEFPVLFFGSNDYLWTHQARVFPYMEGDVSSKDKMGKGVDGTYKKALQEAAARFEELKAQKELRQLQEDRKNDKKPPPYKHIKVNRPIGRVQIFTADLSEIPRCNCKATDENPCGIDSECINRMLLYECHPTVCPAGGRCQNQCFSKRQYPDVEIFRTLQRGWGLRTKTDIKKGEFVNEYVGELIDEEECRARIRYAQEHDITNFYMLTLDKDRIIDAGPKGNYARFMNHCCQPNCETQKWSVNGDTRVGLFALSDIKAGTELTFNYNLECLGN-GKTVCKCGAPNCSGFLGVRPKNQPIVTEEKSRKFKRKPHGKRRSQGEVTKEREDECFSCGDGGQLVSCKKPGCPKVYHADCLNLTKRPAGKWECPWHQCDVCGKEAASFCEMCPSSFCKQHREGMLFISKLDGRLSCTEHDPCGPNPLEPGEIREYVPPTATLSPSPGTQQTEQSSEMGTQGPKKSDQPPTDATQMLSLSKKAVTGTCQRPLLPERPPERTDSSSHLLDRIRDLAGSGTKSQSLVSSQRPQDRPPAKEGPRPQPPDRASPVTRPSSSPSVSSLPLERPLRMTEPRLDKSIGAASPKSQAVEKPPAPTGLRLSSPDRLLNTNSPKPQISDRPPDKSHASLTQRLPPPEKVLSAVVQSLVAKEKALRPVDQNTQAKHRAAVVMDLIDLTPRQKERAASPQEVTAQADEKTPVLESSSRPTSRGLGHVPRAVEKGGVSDPLQPPGKSAAPSEHPWQAVKSLTHARFLSPPSAKAFLYESAIQASGRAPVGSEQTPGPPSPAPGLLKQVKQLSRG-----LTAKSGQSFRSLGKISASLPNEEKKLTTTEQSPWGLGKASPGAGLWPIVAGQTLAQACWSSGGTQTLAQNCWSLGRGQDPKPEQNAIQALNQAPSSRKCAESEQK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88491-1", "uniprot_id": "NSD1_MOUSE", "id": "O88491-1", "name": "Histone-lysine N-methyltransferase, H3 lysine-36 specific", "aln": "MDRTCELSRRNCLLSFSNPVNLDASEDKDSPFGNGQSNFSEPLNGCTMQLPTAASGTSQNAYGQDSPSCYIPLRRLQDLASMIN---VEYLSGSADGSESFQDPAKSDSRAQSPIVCTSLSPGGPTALAMKQEPTCNNSPELQLRVTKTTKNGFLHFENFTGVDDADVDSEMDPEQPVTEDESIEEIFEETQTNATCNYEPKSENGVEVAMGSEQDSMPESRHGAVERPFLPLAPQTEKQKNKQRSEVDGSNEKTALLPAPTSLGDTNVTVEEQFNSINLSFQDDPDSSPSPLGNMLEIPGTSSPSTSQELPF-------------------------------------------------------------------------------------------------------VPQKILSKWEASVGLAEQYDVPK-GSKNQKCVSSSVKLDSEEDMPFEDCTNDPDSEH-LLLNGCLKSLAFDSEHSADEKEKPCAKSRVRKSSDNIKRTSVKKDLVPFESRKEERRGKIPDNLGLDFISGGVSDKQASNELSRIANSLTGSSTAPGSFLFSSSVQNTAKTDFETPDCDSLSGLSESALISKHSGEKKKLHPGQVCSSKVQLCYVGAGDEEKRSNSVSVSTTSDDGCSDLDPTEHNSGFQNSVLGITDAFDKTENALSVHKN-ETQYSRYPVTN-RIKEKQKSLITNSHADHLMGSTKTMEPETAELSQVNLSDLKISSPIPKPQPEFRNDGLTTKFSAPPGIRNENPLTKGGLANQTLLPLKCRQPKFRSIKCKHKESPAVAETSATSEDLSLKCCSSDTNGSPLANISKSGKGEGLKLLNNMHEKTRDSSDIETAVVKHVLSELKELSYRSLSEDVSDSGTAKASKPLLFSSASSQNHIPIEPDYKFSTLLMMLKDMHDSKTKEQRLMTAQNLASYRTPDRGDCSSGSPVGTSKVLVLGSSTPNSEKPGDSTQDSVHQSPGGGDSALSGELSSSLSSLASDKRELPACGKIRSNCIPRRNCGRAKPSSKLRETISAQMVKPSVNPKALKTERKRKFSRLPAVTLAANRLGNKESG-SVNGPSRGGAEDPGKEEPLQQMDLLRNED-THFSDVHFDSKAKQSDPDKNLEKEPSFENRKGPELGSEMNTENDELHGVNQVVPKKRWQRLNQRRPKPGKRANRFREKENSEGAFGVLLPADAVQKAREDYLEQRAPPTSKPEDSAADPNHGSHSESVAPRLNVCEKSSVGMGDVEKETGIPSLMPQTKLPEPAIRSEKKRLRKPSKWLLEYTEEYDQIFAPKKKQKKVQEQVHKVSSRCEDESLLARCQPSAQNKQVDENSLISTKEEPPVLEREAPFLEGPLAQSDLGVTHAELPQLTLSVPVAPEASPRPALESEELLVKT-------PGNYESKRQRKPTKKLLE-SNDLDPGFMPKKGDLGLSRKCFEASRSGNGIVESRATSHLKEFSGGTTKIFDKPRKRKRQRLVTARVHYKKVKKEDLTKDTPS-SEGELLIHR-----TAASPKEILEEGVEHDPGMSASKKLQVERGGGAALKENVCQNCEKLGELLLCEAQCCGAFHLECLGLPEMPRGKFICNECHTGIHTCFVCKQSGEDVKRCLLPLCGKFYHEECVQKYPPTVTQNKGFRCPLHICITCHAANPAN--VSASKGRLMRCVRCPVAYHANDFCLAAGSKILASNSIICPNHFTPRRGCRNHEHVNVSWCFVCSEGGSLLCCDSCPAAFHRECLNIDIPE-GNWYCNDCKAGKKPHYREIVWVKVGRYRWWPAEICHPRAVPSNIDKMRHDVGEFPVLFFGSNDYLWTHQARVFPYMEGDVSSKDKMGKGVDGTYKKALQEAAARFEELKARKELRQLQEDRKNDKKPPPYKHIKVNRPIGRVQIFTADLSEIPRCNCKATDENPCGIDSECINRMLLYECHPTVCPAGVRCQNQCFSKRQYPDVEIFRTLQRGWGLRTKTDIKKGEFVNEYVGELIDEEECRARIRYAQEHDITNFYMLTLDKDRIIDAGPKGNYARFMNHCCQPNCETQKWSVNGDTRVGLFALSDIKAGTELTFNYNLECLGN-GKTVCKCGAPNCSGFLGVRPKNQPIVTEEKSRKFKRKPHGKRRSQGEVTKEREDECFSCGDAGQLVSCKKPGCPKVYHADCLNLTKRPAGKWECPWHQCDVCGKEAASFCEMCPSSFCKQHREGMLFISKLDGRLSCTEHDPCGPNPLEPGEIREYVPPTATSPPSPGTQPKEQSSEMATQGPKKSDQPPTDATQLLPLSKKALTGSCQRPLLPERPPERTDSSSHLLDRIRDLAGSGTKSQSLVSSQRPQDRPPAKEGPRPQPPDRASPMTRPSSSPSVSSLPLERPLRMTDSRLDKSIGAASPKSQAVEKTPASTGLRLSSPDRLLTTNSPKPQISDRPPEKSHASLTQRLPPPEKVLSAVVQSLVAKEKALRPVDQNTQSKHRPAVVMDLIDLTPRQKERAASPQEVTPQADEKTAMLESSSWPSSKGLGHIPRATEKISVSESLQPSGKVAAPSEHPWQAVKSLTHARFLSPPSAKAFLYESATQASGRTPVGAEQTPGPPSPAPGLVKQVKQLSRG-----LTAKSGQSFRSLGKISASLPNEEKKLTTTEQSPWGLGKASPGAGLWPIVAGQTLAQACWSAGGTQTLAQTCWSLGRGQDPKPE-NAIQALNQAPSSRKCADSEKK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96L73-1", "uniprot_id": "NSD1_HUMAN", "id": "Q96L73-1", "name": "Histone-lysine N-methyltransferase, H3 lysine-36 specific", "aln": "MDQTCELPRRNCLLPFSNPVNLDAPEDKDSPFGNGQSNFSEPLNGCTMQLSTVS-GTSQNAYGQDSPSCYIPLRRLQDLASMIN---VEYLNGSADGSESFQDPEKSDSRAQTPIVCTSLSPGGPTALAMKQEPSCNNSPELQVKVTKTIKNGFLHFENFTCVDDADVDSEMDPEQPVTEDESIEEIFEETQTNATCNYETKSENGVKVAMGSEQDSTPESRHGAVKSPFLPLAPQTETQKNKQRNEVDGSNEKAALLPAPFSLGDTNITIEEQLNSINLSFQDDPDSSTSTLGNMLELPGTSSSSTSQELPFCQPKKKSTPLKYEVGDLIWAKFKRRPWWPCRICSDPLINTHSKMKVSNRRPYRQYYVEAFGDPSERAWVAGKAIVMFEGRHQFEELPVLRRRGKQKEKGYRHKVPQKILSKWEASVGLAEQYDVPK-GSKNRKCIPGSIKLDSEEDMPFEDCTNDPESEHDLLLNGCLKSLAFDSEHSADEKEKPCAKSRARKSSDNPKRTSVKKGHIQFEAHKDERRGKIPENLGLNFISGDISDTQASNELSRIANSLTGSNTAPGSFLFSSCGKNTAKKEFETSNGDSLLGLPEGALISKCSREKNKPQRSLVCGSKVKLCYIGAGDEEKRSDSISICTTSDDGSSDLDPIEHSSESDNSVLEIPDAFDRTENMLSMQKNEKIKYSRFAATNTRVKAKQKPLISNSHTDHLMGCTKSAEPG-TETSQVNLSDLKASTLVHKPQSDFTNDALSPKFNLSSSISSENSLIKGGAANQALLHSKSKQPKFRSIKCKHKENPVMAEPPVINEECSLKCCSSDTKGSPLASISKSGKVDGLKLLNNMHEKTRDSSDIETAVVKHVLSELKELSYRSLGEDVSDSGTSKPSKPLLFSSASSQNHIPIEPDYKFSTLLMMLKDMHDSKTKEQRLMTAQNLVSYRSPGRGDCSTNSPVGVSKVLVSGGSTHNSEKKGDGTQNSANPSPSGGDSALSGELSASLPGLLSDKRDLPASGKSRSDCVTRRNCGRSKPSSKLRDAFSAQMVKNTVNRKALKTERKRKLNQLPSVTLDAVLQGDRERG----GSLRGGAEDPSKEDPLQIMGHLTSEDGDHFSDVHFDSKVKQSDPGKISEKGLSFENGKGPELDSVMNSENDELNGVNQVVPKKRWQRLNQRRTKPRKRMNRFKEKENSECAFRVLLPSDPVQEGRDEFPEHRTPSASILEEPLTEQNHADCLDSAGPRLNVCDKSSASIGDMEKEPGIPSLTPQAELPEPAVRSEKKRLRKPSKWLLEYTEEYDQIFAPKKKQKKVQEQVHKVSSRCEEESLLARGRSSAQNKQVDENSLISTKEEPPVLEREAPFLEGPLAQSELGGGHAELPQLTLSVPVAPEVSPRPALESEELLVKT-------PGNYESKRQRKPTKKLLE-SNDLDPGFMPKKGDLGLSKKCYEAGHLENGITESCATSYSKDFGGGTTKIFDKPRKRKRQRHAAAKMQCKKVKNDDSSKEIPG-SEGELMPHR-----TATSPKETVEEGVEHDPGMPASKKMQGERGGGAALKENVCQNCEKLGELLLCEAQCCGAFHLECLGLTEMPRGKFICNECRTGIHTCFVCKQSGEDVKRCLLPLCGKFYHEECVQKYPPTVMQNKGFRCSLHICITCHAANPAN--VSASKGRLMRCVRCPVAYHANDFCLAAGSKILASNSIICPNHFTPRRGCRNHEHVNVSWCFVCSEGGSLLCCDSCPAAFHRECLNIDIPE-GNWYCNDCKAGKKPHYREIVWVKVGRYRWWPAEICHPRAVPSNIDKMRHDVGEFPVLFFGSNDYLWTHQARVFPYMEGDVSSKDKMGKGVDGTYKKALQEAAARFEELKAQKELRQLQEDRKNDKKPPPYKHIKVNRPIGRVQIFTADLSEIPRCNCKATDENPCGIDSECINRMLLYECHPTVCPAGGRCQNQCFSKRQYPEVEIFRTLQRGWGLRTKTDIKKGEFVNEYVGELIDEEECRARIRYAQEHDITNFYMLTLDKDRIIDAGPKGNYARFMNHCCQPNCETQKWSVNGDTRVGLFALSDIKAGTELTFNYNLECLGN-GKTVCKCGAPNCSGFLGVRPKNQPIATEEKSKKFKKKQQGKRRTQGEITKEREDECFSCGDAGQLVSCKKPGCPKVYHADCLNLTKRPAGKWECPWHQCDICGKEAASFCEMCPSSFCKQHREGMLFISKLDGRLSCTEHDPCGPNPLEPGEIREYVPPPVPLPPGPSTHLAEQSTGMAAQAPKMSDKPPADTNQMLSLSKKALAGTCQRPLLPERPLERTDSRPQPLDKVRDLAGSGTKSQSLVSSQRPLDRPPAVAGPRPQLSDKPSPVTSPSSSPSVRSQPLERPLGTADPRLDKSIGAASPRPQSLEKTSVPTGLRLPPPDRLLITSSPKPQTSDRPTDKPHASLSQRLPPPEKVLSAVVQTLVAKEKALRPVDQNTQSKNRAALVMDLIDLTPRQKERAASPHQVTPQADEKMPVLESSSWPASKGLGHMPRAVEKGCVSDPLQTSGKAAAPSEDPWQAVKSLTQARLLSQPPAKAFLYEPTTQASGRASAGAEQTPGPLSQSPGLVKQAKQMVGGQQLPALAAKSGQSFRSLGKAPASLPTEEKKLVTTEQSPWALGKASSRAGLWPIVAGQTLAQSCWSAGSTQTLAQTCWSLGRGQDPKPEQNTLPALNQAPSSHKCAESEQK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8MT36-1", "uniprot_id": "NSD_DROME", "id": "Q8MT36-1", "name": "Nuclear receptor binding SET domain protein", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------MKLSTDAHSEIEGDAAHGNVLCNSASDSLTATDEVAAGND------ESVATEGDDVEIPRDTNNSTPVRLLDKPGQNPVQNGAQPAAEESELESQRQTPVQKQQQ-------------------------------------------------------QRVSMVNRKRDLIN-------------------------------------------------------------------------------------------------------LQSALSPKYIGYANANSPTPLSD-SDDTIRTTRRRVNQAAALNNSSAGETLAHDNASPRTPGG----------GGGGGGDDSANQLLSKTYMSPIEKLLIKNGASSPNS---------------TGFEAGSEDLGIRPIVRKHVKRKMKRVPKAKVTLELDEKNQQEVDEKSVKTEP----------------------------------------IDEEVDRTDEAPTQEAQTTAISIKSETEAEHKAAVDVHIKQEDTIRLDIVNNP-------VESTSIVITEEPKDLEKSTEELAFALPLASSTEVDLKSPPD-----------------------LSSTALATSIKSPSSVSIDSAKGLSIVTDPG-WPTYQVGDLFWGKVFSYCFWPCMVCPDPLGQIVGNMPSHPQRSS------------------------------LDNANVPIQVHVRFFADNGRR------------------NWIKPENLLTFAGLKAFDDMREELRIKHG----------------------------------------------------------------PKSAKYRQMVPKRTKVVIWRQAIEEAQAMTQIPYSDRLEKFYQTYENVVTLNRQKRKRTKYMMQDTS--------------------------------------------------------DVGSSLYDSTDNLHNKQGTQLLAVKRERSESPFSPAFSPVKSKNEKRAKRRKLSNGTEADTG----------------------------------SNSMAVTPSQTETTVDSS------------------------------------------AYENPEFRQLLSAVMEYVMMNRSDEKVEKVLLSVVSNIWSLKQIQLRELERDLASGEIEEPLGSSVVG-----------------RGSGVGTIKRLSNRLMTMMVRRSMTPVVTPSTTPAPSEPDRRLSEPP----------KTKKPVNRPIEEVIEDILQLDSKYLFR-GLSREPICKYCYQAGSDLVRCSRTCSSWLHADCLERKVTGAPMPKIGSRKALVIPPTSKSPSPDED---------------------------------------HVTADAKEVVAVGTSLVCHECNVGEPEG--------CVICHQVESPAVPSTPRK-----------EDSSSHTPIEDKLLTCSQPMCGKRFHTSCCKYWPQASSSKHSARCPRHVCHTCVSDDPSGKFQQLGSSKLAKCVRCPATYHQLSKCIPAGTQMLNTTNIICPRHNIAK----ADAHVNVLWCYICVKGGELVCCETCPIAVHAHCRNIPIKTNESYICEECESGRLPLYGEIVWAKFNNFRWWPAIILPPTEVPSNILKKAHGENDFVVRFFGTHDHGWISRRRVYLYIEGDTGDGHKTKSQLFRNYTTGVEEASRFLPIIKARRQEQDMERQSGNKLHPPPYVKIKTNKAVP-PLRFSQNLEDLSTCNCLPVDEHPCGPEAGCLNRMLFNECNPEYCKAGSLCENRMFEQRKSPRLEVVYMNERGFGLVNREPIAVGDFVIEYVGEVINHAEFQRRMEQKQRDRDENYYFLGVEKDFIIDAGPKGNLARFMNHSCEPNCETQKWTVNCIHRVGIFAIKDIPVNSELTFNYLWDDLMNNSKKACFCGAKRCSGEIGGKLKDDAVKAHAKLKQMRR----------------------AKASAVRIHVKPKKTPKVKHISADDEPMDAKDE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . .. * : : ..: . : :. .. : .: . .: * : . : .: . . . . : . . .. . : . . :.: :. :.. .* : . . : . : . . . . . . : : . . . . : . . . .: . . . . . :: : : .: : : .*: : : . .: : *. . : . . : . . : . . . :. : . .*:* . : . : . .* ::: .. : .. ::: . . . : .: : .. . * .:. .:::: : :. : : . . . . : . . .::: : * * * * ..: :. .: . * . . . ..: * * *** :* .* . : ::. **. * * :* :* . ...:* :*:***.:** . *:.**: * ..::**.* .: . *:** **::* :**.*:**::** *.* .* ** : .: *::*.:*: * * :::*.*...:***** : * :*.** : * .:* * ***::*: * : * : *:***... .* . *...::**: : : .:: ::::.: *. :**** :**.*: . :: :*.::. *** ..**:*** :: *:****: **:. * ** *:*: * :*: :* . .**:** * * *: *****:*:. * : *:. * . *:*:* ::** ********* :*****.*:********:** ***:*:: ** . ****** : * * .*..* *** .*** :* : *::. . * ::::: . .. : * *** * .. : . . .. ", "identical_positions": 200, "similar_positions": 346, "identity": "7.34%" }, { "cls_id": "homologset.agr.MGI:1276549", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P61808-1", "uniprot_id": "SNN_RAT", "id": "P61808-1", "name": "Stannin", "aln": "MSIMDHSPTTGVVTVIVILIAIAALGALILGCWCYLRLQRISQSEDEESIVGDGETKEPFLLVQYSAKGPCVERKAKLMTANSPEVHG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P61807-1", "uniprot_id": "SNN_MOUSE", "id": "P61807-1", "name": "Stannin", "aln": "MSIMDHSPTTGVVTVIVILIAIAALGALILGCWCYLRLQRISQSEDEESIVGDGETKEPFLLVQYSAKGPCVERKAKLMTANSPEVHG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75324-1", "uniprot_id": "SNN_HUMAN", "id": "O75324-1", "name": "Stannin", "aln": "MSIMDHSPTTGVVTVIVILIAIAALGALILGCWCYLRLQRISQSEDEESIVGDGETKEPFLLVQYSAKGPCVERKAKLMTPNGPEVHG", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "********************************************************************************.*.*****", "identical_positions": 86, "similar_positions": 2, "identity": "97.73%" }, { "cls_id": "homologset.agr.MGI:1276558", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ES88-1", "uniprot_id": "S13A2_MOUSE", "id": "Q9ES88-1", "name": "Solute carrier family 13 member 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MATCWQALWAYRSYLIVLCLPIFLLPLPLIVQTKEAYCAYSIILMALLWCTEALPLAVTALFPIILFPLMGIME---------------------------------------------ASKVCLEYFKDTNILFVGGLMVAIAVEHWN-------------------------------------LHKRIALGVLLIIGVRPAL------------LLLGFMLVTAFLSMWISN--------TATTAMMLPIGYAVLEQLQGSQK--DVEEGNSNPSFELQEASPQKEETKLDNGQA---VSVSSEPRAQKTKEHHRFSQGLSLCICYSASIGGIATLTGTTPN-LVLQGQVNSIFPENSNVVNFASWFGFAFP-TMVILLLLAWLWLQVLFLGVNFRKNFGFGEGEE---ERKQAAFQVIKTQHRLLGPMSFAEKAVTFLFVLLVVLWFTREPGFFPGWGDTAFANKKGQSMVSDGTVAIFISLIMFIIPSKIPGLTEDPKKPGKLKAP--PAILTWKTVN----DKMPWNILILLGGGFALAKGSEESGLSKWLGDKLTPLQHVP-PSATVLILSLLVAIFTECTSNVATTTLFLPILASMAQAIC--LHPLYVMLPCTLAASLAFMLPVATPPNAIVFSFGGLKVSDMARAGFLLN--IIGVLTITLSINSWSIPIFK-LDTFPTWAYSN-TSQCLLNPPNSTVPGH-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P70545-1", "uniprot_id": "S13A2_RAT", "id": "P70545-1", "name": "Solute carrier family 13 member 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MATCWPALWAYRFYLIVLCLPIFLLPLPLIVQTKEAYCAYSIILMALLWCTEALPLAVTALFPIVLFPLMGIMD---------------------------------------------ASEVCIEYFKDTNILFVGGLMVAIAVEHWN-------------------------------------LHKRIALQVLLIIGVRPAL------------LLLGFMLVTAFLSMWISN--------TATTAMMVPIGHAVLEQLQGSKK--DVEGGNNNPTFELQEECPQKEVTKLDNGQP---VSAPSEPRTQKTQEHHRFSQGLSLCICYSASIGGIATLTGTTPN-LVLQGQVNSLFPQNGNVVNFASWFGFAFP-TMIILLLLAWLWLQVLFLGVNFRKNFGFGEGEE---ERKQAAFQVIKTQYRLLGPMSFAEKTVTVLFVLLVVLWFTREPGFFPGWGDTVFANEKGQSMASDGTVAIFISLVMFIIPSKIPGLMQDPKKPGKLKAP--PAILTWKTVN----DKMPWNIVILLGGGFALAKGSEQSGLSEWLGDKLTPLQHIP-PSATAVILCLLIAIFTECTSNVATTTLFLPILASMAQAIC--LHPLYVMLPCTLAASLAFMLPVATPPNAIVFSFGGLKVSDMARAGFLLN--IIGVLAITLSINSWSIPIFK-LDTFPSWAHSN-TSQCLLNPSNSTVPGGL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q13183-1", "uniprot_id": "S13A2_HUMAN", "id": "Q13183-1", "name": "Solute carrier family 13 member 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MATCWQALWAYRSYLIVFFVPILLLPLPILVPSKEAYCAYAIILMALFWCTEALPLAVTALFPLILFPMMGIVD---------------------------------------------ASEVAVEYLKDSNLLFFGGLLVAIAVEHWN-------------------------------------LHKRIALRVLLIVGVRPAP------------LILGFMLVTAFLSMWISN--------TATSAMMVPIAHAVLDQLHSSQASSNVEEGSNNPTFELQEPSPQKEVTKLDNGQALPVTSASSEGRAHLSQKHLHLTQCMSLCVCYSASIGGIATLTGTAPN-LVLQGQINSLFPQNGNVVNFASWFSFAFP-TMVILLLLAWLWLQILFLGFNFRKNFGIGEKMQ---EQQQAAYCVIQTEHRLLGPMTFAEKAISILFVILVLLWFTREPGFFLGWGNLAFPNAKGESMVSDGTVAIFIGIIMFIIPSKFPGLTQDPENPGKLKAP--LGLLDWKTVN----QKMPWNIVLLLGGGYALAKGSERSGLSEWLGNKLTPLQSVP-APAIAIILSLLVATFTECTSNVATTTIFLPILASMAQAIC--LHPLYVMLPCTLATSLAFMLPVATPPNAIVFSFGDLKVLDMARAGFLLN--IIGVLIIALAINSWGIPLFS-LHSFPSWAQSNTTAQCLPSLANTTTPSP-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E1JIQ7-1", "uniprot_id": "E1JIQ7_DROME", "id": "E1JIQ7-1", "name": "Protein I'm not dead yet 2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MG-------------------DADGKIGGGQAVKRCCGFHWRGKATAMIPLITLPIMIYGVLENNLAFQCMYLVANMALFWITEAIPLYLTALFPVVFLPLFGILT---------------------------------------------SEKVCSFYFSDTVVMFIGGLLIALAIEYSN-------------------------------------LHQRIALNTILIVGCSPRR------------LHFGLVMVTCFISLWISN--------SAATAMMCPIVKAVLNEMETQNI---------FAIYKTQEEEPVE------EGDPP---------------HPSTISMAFYFGIAYSSSIGGCGTLIGTGTN-LTYKGLYDTRFPNSDEKIDFPIFMAYSVPFVVLVLIFLTYFSLQVTHMGL-FRPNSKIGQEVKKGAESQDVVKDVIKQRKAELGPMSCHEIQVGLLFVLMIFLLFTRKPGFFPGWADFLNAKA-----IGSGPPVFFATILLFALPTQYTFFKYCCGKA-PFPGQTLDACLSWVYCQ----KYTPFGLAFLLGGGFALAEGSRVSGMAKMLGESLAFAGEMH-SVLVISMCIIISLFCTAFASNVAICNILIPIFSEMALAIE--VHPMKLTFPAALACSLAFHLPVSTPPNAIISGFTGLKTKYMAIAGILPT--CWAFLCLLFTGTVWTMLIYPGTTEFPSWAI--------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VDQ0-1", "uniprot_id": "INDY2_DROME", "id": "Q9VDQ0-1", "name": "Protein I'm not dead yet 2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MA-------------------EPGEQRK--FVLGRCCIFHWRGKASIIIPLITLPILIYGFQTDMAEFKCLWLIVTMALLWITETLPIYVTALFPLVFCPLLGLVN---------------------------------------------ASIVCKQYFTDTIVVFLGGLIVALGIEYSN-------------------------------------LHTRIALRVIRIVGGSPRR------------LFVGLMSVSTFMGLWISN--------SAGTAMMCPIVKALVNELDTNKI---------FPVYMTQEEEPVE------EGEPP---------------HPSKITVAFYAGIAYASSIGGLGTLIGTGTN-LVFRGIYTERFPTSTVEITFANFMFYSIPLMVIVNVTLVIIAFLITHMGL-FRPNSKTGKIIAEANTNRKLMEDVLRQRHIDLGPMSCHEIQMAIAFAFMIVLLITRKPGFVPGWSDLINRKV-----VGSASGLSFIVLLIFALPTQYTFFKYCCGKG-PFTAQAIDAILSWEYVL----RNIPWGLLFLLGGGFALAVASRETGLNIMISKAMQVLIGLP-NIVVQSITFVLANFFSAFNANVVVANIVLPILCEMSLALE--LHPLILTLPACLGISMVYFLPVSTPPNAIVTQYAHIKTKYFACCGIVPT--IIGISVALVNTNTWGLIIFPESKSFPDWAKEI-KNQTKI-----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VVT2-1", "uniprot_id": "INDY1_DROME", "id": "Q9VVT2-1", "name": "Protein I'm not dead yet", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MATETTKMIYTPPPLDIKMEIEIGEQPQPPVKCSNFFANHWKGLVVFLVPLLCLPVMLL---NEGAEFRCMYLLLVMAIFWVTEALPLYVTSMIPIVAFPIMGIMS---------------------------------------------SDQTCRLYFKDTLVMFMGGIMVALAVEYCN-------------------------------------LHKRLALRVIQIVGCSPRR------------LHFGLIMVTMFLSMWISN--------AACTAMMCPIIQAVLEELQAQGV---------CKINHEPQYQIVGGNKKNNEDEPP---------------YPTKITLCYYLGIAYASSLGGCGTIIGTATN-LTFKGIYEARFKNSTEQMDFPTFMFYSVP-SMLVYTLLTFVFLQWHFMGL-WRPKSKEAQEVQRGREGADVAKKVIDQRYKDLGPMSIHEIQVMILFIFMVVMYFTRKPGIFLGWADLLNSKD-----IRNSMPTIFVVVMCFMLPANYAFLRYCTRRGGPVPTGPTPSLITWKFIQ----TKVPWGLVFLLGGGFALAEGSKQSGMAKLIGNALIGLKVLP-NSVLLLVVILVAVFLTAFSSNVAIANIIIPVLAEMSLAIE--IHPLYLILPAGLACSMAFHLPVSTPPNALVAGYANIRTKDMAIAGIGPT--IITIITLFVFCQTWGLVVYPNLNSFPEWAQIY-AAAALGNKTH-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39535-1", "uniprot_id": "PHO90_YEAST", "id": "P39535-1", "name": "Low-affinity phosphate transporter PHO90", "aln": "MRFSHFLKYNAVPEWQNHYMDYSELKNLIYTLQTDELQ-------------------VGDNEEGFGAGKSSNITDRFKNKFSFKNAKEDTSSGMNKDAG---------IVEETIELRELPTAQTVAAKPSPFRRMKEKIFYKRRSSSASSVSSTANENLQLDTYDTFVGDLTAEKQKVDDFYKRTEAKFYDKFDALVKDLKKIGVIE-------YDIDDDTLFNEPIASTND--------EVPPLDLD-----------DDEDDDEFYDDQSNIEDNTALLHHSQYNIKSQKKSLLKKSIVNLYIDLCQLKSFIELNRIGFAKITKKSDKVLHLNTRTELIESEQFFKDTYAFQAETIELLNSKISQLVTFYARITD---RPHN-------------------------------ISHSKQELKSYLHDHIVWERSNTWKDMLGLLSQADELTPKETEYNAN---------KLVGKLDLEYYRWPLPRPINLKFTSINNVALPK---LFFTKKAYKIYFIILVTGLLLGIKTFN------DAAQHRCMALVECVAFLWASEAIPLHITAFLVPLLVVLFKVLKT-SDGAIMSAASASSEILAAMWSSTIMILLAGFTLGEVLAQYNIAKVLASWLLAFAGCKPRNVLLMAMCVVFFLSMWISNVAAPVLTYSLLSPLLDAMDADSPFAQALVLGVALAANIG-GMSSPISSPQNIISMSYLKPYGIGWGQFFAVALPSGILAMLLVWILLFTTFKMN--KTKLEKFKPIKTKFTVKQYYIITVTVATILLWCVESQIEGAFGSSGQIAIIPIVLFFGTGLLSTQDLNAFPWSIVILAMGGIALGKAVSSSGLLSTIAKALQKKIENDGVFAILCIFGILMLVVGTFVSHTVSAIIIIPLVQEVGDKLGNPKAAPILVFGCALLSSCGMGLASSGFPNVTAISKVDRKGDRYLSVMTFLTRGVPASILAFLCVITLGYGIMASVVKGNATSA--------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P25360-1", "uniprot_id": "PHO87_YEAST", "id": "P25360-1", "name": "Inorganic phosphate transporter PHO87", "aln": "MRFSHFLKYNAVPEWQNHYLDYNELKNLIYTLQTDELKQETPTGDLNDDADSQTPGPIADIESNIAAGEPSSSKRRFTHKLKRKLFGSKTPSGSKRGDSDEKAIDGNNINEETIELDELSPQGKTTSFNKNFIR---KKFFESRSSSVSSEGKTL-----FSSYDTFVTNLSDEKLKVDDFYKRMEAKFYERFDHLINDLEKEGIVTRLNETFNPEIQALPPLREIISGTSETHSSNNPFEIHSSNIDSELRNRFDYSEEEMDEDDDVDVFADTTDNTALLNYSQFNIKSQKKSLLKQTIINLYIDLCQLKSFIELNRMGFSKITKKSDKVLHMNTRQELIESEEFFKDTYIFQHETLSSLNSKIAQLIEFYAVLMG---QPGN-------------------------------VDSCKQELKSYLHDHIVWERSNTWKDMLGLSSQNNDIITIEDEAEK----------LMQEKLQIEYFKYPLPKPINLKFTKIENLAVPK---LFFGKRAMKIGFIIIVTGVLLGVKTFN------DPVEHRCMALVECCAFLWASEAIPLHITGLLVPLLTVLFRVLKD-DDGKVMGAAAASTEILGTMWSSTIMILLAGFTLGEALSQYNVAKVLASWLLALAGTKPRNVLLMAMSVVFFLSMWISNVASPVLTYSLLTPLLDPLDYTSPFAKALVMGVALSADIG-GMASPISSPQNIISMQYLKPYGIGWGQFFAVALPTGILSMLCSWALMILTFKIG--KTKLEKFKPIRTRFTIKQYFIIIVTIATILLWCVESQIESAFGSSGEIAVIPIVLFFGTGLLSTKDFNTFPWSIVVLAMGGIALGKAVSSSGLLVTIARALQKKIQNDGVFAILCIFGILMLVVGTFVSHTVSAIIIIPLVQEVGDKLSDPKAAPILVFGCALLASCGMGLASSGFPNVTAISMTDKKGNRWLTVGAFISRGVPASLLAFVCVITLGYGISSSVLKGST-----------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P27514-1", "uniprot_id": "PHO91_YEAST", "id": "P27514-1", "name": "Low-affinity phosphate transporter PHO91", "aln": "MKFSHSLQFNSVPEWSTKYLAYSQLKKLIYSLQKDKLY--------------------SNNKHHVVEPHDANDEN---LPLLADASPDDQFYISKFVAA---------LNQELKKIDKFYISQETGLIAN----------YNELKDDVMELENTN------KATQLFNQQQQHQLQSVARNRKSKSQQRQRRFSSVSSTDSNPSLTD-------MSIDSAPVIHTQVSNTTN----------------------------NGNSMQNLASASVSLSNSNPVYLSPF---TQHRLSLKKRLISIYTQLSELKDFIELNQTGFSKICKKFDKSLNTNLKQNYLNYIKFHS--HVFNPATINRIQHHITETILTYASLNKGTRRPSNTFNLDADRINNDENSSGNEEDEDGNRQEVLDFQDAERELSSHLRDHVVWERNTVWKDMMNLERKYQSAKTDNKKFSKLSSSQLRPNANITESMAMSSGGAGIIAPSTDSLTFRELMHLPPKQWLQFIMGQTSLLKFLLITSCFIALLTFNLTPFTQDSLQKNCFAILIYASLLWATETIPLFVTSLMIPLLIVVFPVIKDPITSQPMSPRDSSQFILSTMWSSVIMLLLGGFTLAAALSKYNIAKVLSTHILASAGTNPHFILLTNMFVALFVSMWVSNVAAPVLCYSIVQPLLRTLPRNCSYAKALILGIALASNIG-GMSSPIASPQNIFSIGIMDPS-PSWAEWFMIALPVCFICVMAIWVLLIITFPPEP-NVKILQLHPSRDPFTLKQWFVTLVCIITIVLWCLSNQISGIFGEMGIISIIPIVVFFGTGLLTSDDFNNFMWTIVVLAMGGTTLGKAVSSSGLLSTMAQLIKAQVEHEPIFIIVLIFGLVILVMATFVSHTVAAMIIVPLMSEIGSNLPSGDHSRLLIVIAALLCSSAMGLPTSGFPNVTAISMIDEVGDRYLTVGTFITRGVPASLLSYAAIVTVGYGILKVMGF--------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : : : : : . .. :: * : . : : : : :: . ::.: * .: :.: . . : : * .. : * . : ::. :: :*. . . : . . : : . : . : : : : . : : : .* ** :*. . :*: :. : : :: ::.. :.:*:. .:. : . : . . * * *. : **. . : ", "identical_positions": 16, "similar_positions": 98, "identity": "1.58%" }, { "cls_id": "homologset.agr.MGI:1276570", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AHD5-1", "uniprot_id": "A0A8I6AHD5_RAT", "id": "A0A8I6AHD5-1", "name": "", "aln": "MKVLLVLA-VLLLMVTLVITKNPKGSHSLRYLQTLLSWPGLAEPQFIFVGYVGNTQFIGFNSRSQSQWSLHRAPWKDQQTPEYWEKTIQEVLSEKRNLKEVMEKMLHIYPNSTTGNHTIQMRYGCDVLPGGYFSHGILELNFDSQDYIILNDELHNWIIDGKAAEMLKQEWEDTHYAQIVKNYLKGSCVDELLTELDLGKDYLLRTDTPRTHVIHKVRPDRKIILRCWALNFYPAEITITWQRDGRNQTQDVEVIETRPAGDGTFQKWAAVVVPSGEEQKYTCRVEHEGLPEPITLRWESPQSTIPVMAIVLCLVLGALLTGAVVTSLIWKRKIKG------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6GE62-1", "uniprot_id": "A0A8I6GE62_RAT", "id": "A0A8I6GE62-1", "name": "", "aln": "MKTFVHQALLLLLIVTLAITGHPKGLHSLNYKQTLLEWPGFLELQFIAVIYADDIQFLGLNSIWGSSRAENKVPWMDEDEPETSEKVTQSMLDEKDLLTKIMKKVLHIYNYSMTGYHTIQRRRGCYVVPGGHFSHGFVELTFNNHDYIMLNEDLETWSVVGKAAEMIRQDFEEENFAKYMREYLRGPCVEGILGLLQYGEKALLRAGTPKTHVTHKVTADGKITLRCWALNFYPAEITLIWQKDGSNKTQDVEVIETRPSGDGNFQKWAAVVVPSGEEQRFTCHVEHERLPKPITLRWESPQSINSTMAIAIAVVLGALLMGAVLTFFIWKRRTKGKEKQSLSSWLHGNIKPNL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O19442-1", "uniprot_id": "O19442_MOUSE", "id": "O19442-1", "name": "", "aln": "MKNFESQPLLLLFMVTLVIAKHPNGSHTLRFVSTFLSWPRHLELQFIFLIYVDETQIMGFNSISESQRMESRVPWLNELNAEFWELATQDVLKEKSFVTGIMNKLLHIYNDSMTGYHIIQETYGCQVKQRTYFSHAFMELLFDTHDYITLNEDLQTWRAVGKAAEIVKEEWEKINLVKSSKSFLLGACVEGLLQYLNFGKKYLLRTDTPKIHMTYKIRPDRKITLRCWAFNFYPPEITLTWQRDGSNQTQDMEVIEIRPSGDGTFQKWAAVVVSSGEEHRYTCHVNHEGLSEPVTLRWDPPEPTIPFLPMIIALVLGALLMGSVMTFLIWKRRTRGKK----GSWS--------", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** : . :**::***.*: :*:* *:*.: .*:*.** * *** : *..: *::*:** *. :.** :: .* * . *.:*.** :. :*:*:**** * ** * ** ** * :***.::** *:.:*** **::*..* *****::::::*. : .: :.:* *.**: :* *: *:. ***:.**: *: :*: .* ** *****:****.***: **:** *:***:**** **:***.*********.****:::**:*:** *.:*:****:.*:. . :.: :.:****** *:*:* :****: :* ", "identical_positions": 153, "similar_positions": 107, "identity": "43.22%" }, { "cls_id": "homologset.agr.MGI:1276574", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A9J4-1", "uniprot_id": "D4A9J4_RAT", "id": "D4A9J4-1", "name": "Histone-lysine N-methyltransferase NSD2", "aln": "------------------------------------------------------------------------------------MEFSIRKSPLSVQKVVKCMKMKQAPEILGSANGKTQNCEVNHECSVFLSKAQLSNSLQEG-----VMQKFNGHDALPFLPAEKLKDLTSCVFNG-----EPGAHDTKLCFETQE--VKGIG-TPPNTTPIKNG--SPEIKLKITKTYMN--GKP-LFESSICGDGAADMSQ----------SEENGQKSDNKTRRNRKRSIKYDSLLEQGLVEAA--LVSKISS------------------------------------------PEDKKIPVKKESCPNSGRDR-----------------DLLLKYNVGDLVWSKVSGYPWWPCMVSADPLLHNHTKLKGQKKS--------ARQYHVQFFGDAPERAWIFEKSLVAFEGEEQFEKLCQESAKQAPTKAEKIKLLKPISGRLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLRLNP------QVAKEAGIATEPLG----EMVDSSVANEEAAVDPGTMREEDIPVKRRRRAKRSSS----AENQEGDPGTEKSTPPK---------MADAEPKRGVGSPAGRKRSTGSASRSRKGDSAAQFLVFCQKHRDEV-VAEHPDASEEEIEELLGSQWSMLNEKQKARYNTKFSLMISAQSEEDSGNTSGKKRTHTKRTDDPPEDVDVEDAPR--KRLRTDKHSLRKRETITDKTAR--------TSSYKAIEAASSLKSQAATKNLSDA--CKPLKKRNRASATASSALG-FNKSSSPSASLTENEVSDNPGDEPSESPYESADETQTEASVSSKKSERGMAAKKEYVCQLCEKTGS-LLLCEGPCCGAFHLACLGLSQRPEGRFTCTECASGIHSCFVCKESKMEVKRCMVNQCGKFYHEACVKKYPLTVFESRGFRCPLHSCMSCHASNPSN--PRPSKG------------------------------------------------------------GSLLCCEACPAAFHPDCLSIEMPD-GSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAEVCHPKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKNALQEAEARFNEIKLQREARETQE---SERKPPPYKHIKVNKPYGKVQIYTADISEIPKCNCKPTDENPCGSDSECLNRMLMFECHPQVCPAGEYCQNQCFTKRQYPETKIIKTDGKGWGLVAKRDIRKGEFVNEYVGELIDEEECMARIKYAHENDITHFYMLTIDKDRIIDAGPKGNYSRFMNHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGNE-KTVCRCGASNCSGFLGDRPKTSTSLSSEEKSKKAKKKTRRRRAKGEGKRQSEDECFRCGDGGQLVLCDRKFCTKAYHLSCLGLGKRPFGKWECPWHHCDVCGKPSTSFCHLCPNSFCKEHQDGTAFRSTQDGQSYCCEHDLRADSANNTKTEKPFLDSLKAKGKRKKRRCWRRVTDGK--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BVE8-1", "uniprot_id": "NSD2_MOUSE", "id": "Q8BVE8-1", "name": "Histone-lysine N-methyltransferase NSD2", "aln": "------------------------------------------------------------------------------------MEFSIRKSPLSVQKVVKCMKMKQTPEILGSANGKTQNCEVNHECSVFLSKAQLSNSLQEG-----VMQKFNGHDALPFLPAEKLKDLTSCVFNG-----EPGAHDTKLCFEAQE--VKGIG-TPPNTTPIKNG--SPEIKLKITKTYMN--GKP-LFESSICGDGAADVSQ----------SEENEQKSDNKTRRNRKRSIKYDSLLEQGLVEAA--LVSKISS------------------------------------------PADKKIPVKKESCPNTGRDR-----------------DLLLKYNVGDLVWSKVSGYPWWPCMVSADPLLHNHTKLKGQKKS--------ARQYHVQFFGDAPERAWIFEKSLVAFEGEEQFEKLCQESAKQAPTKAEKIKLLKPISGRLRAQWEMGIVQAEEAASMSIEERKAKFTFLYVGDQLHLNP------QVAKEAGIVTEPLG----EMVDSSGASEEAAVDPGSVREEDIPTKRRRRTKRSSS----AENQEGDPGTDKSTPPK---------MAEAEPKRGVGSPAGRKKSTGSAPRSRKGDSAAQFLVFCQKHRDEV-VAEHPDASGEEIEELLGSQWSMLNEKQKARYNTKFSLMISAQSEEDSGNGNGKKRSHTKRADDPAEDVDVEDAPR--KRLRADKHSLRKRETITDKTAR--------TSSYKAIEAASSLKSQAATKNLSDA--CKPLKKRNRASATASSALG-FNKSSSPSASLTEHEVSDSPGDEPSESPYESADETQTEASVSSKKSERGMAAKKEYVCQLCEKTGS-LLLCEGPCCGAFHLACLGLSRRPEGRFTCTECASGIHSCFVCKESKMEVKRCVVNQCGKFYHEACVKKYPLTVFESRGFRCPLHSCMSCHASNPSN--PRPSKGKMMRCVRCPVAYHGGDACLAAGCSVIASNSIICTGHFTARKGKRHHTHVNVSWCFVCSKGGSLLCCEACPAAFHPDCLNIEMPD-GSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAEVCHPKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKNALQEAEARFNEVKLQREARETQE---SERKPPPYKHIKVNKPYGKVQIYTADISEIPKCNCKPTDENPCGSDSECLNRMLMFECHPQVCPAGEYCQNQCFTKRQYPETKIIKTDGKGWGLVAKRDIRKGEFVNEYVGELIDEEECMARIKYAHENDITHFYMLTIDKDRIIDAGPKGNYSRFMNHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGNE-KTVCRCGASNCSGFLGDRPKTSASLSSEEKGKKAKKKTRRRRAKGEGKRQSEDECFRCGDGGQLVLCDRKFCTKAYHLSCLGLGKRPFGKWECPWHHCDVCGKPSTSFCHLCPNSFCKEHQDGTAFRSTQDGQSYCCEHDLRADSSSSTKTEKPFPESLKSKGKRKKRRCWRRVTDGK--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O96028-1", "uniprot_id": "NSD2_HUMAN", "id": "O96028-1", "name": "Histone-lysine N-methyltransferase NSD2", "aln": "------------------------------------------------------------------------------------MEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEG-----VMQKFNGHDALPFIPADKLKDLTSRVFNG-----EPGAHDAKLRFESQE--MKGIG-TPPNTTPIKNG--SPEIKLKITKTYMN--GKP-LFESSICGDSAADVSQ----------SEENGQKPENKARRNRKRSIKYDSLLEQGLVEAA--LVSKISS------------------------------------------PSDKKIPAKKESCPNTGRDK-----------------DHLLKYNVGDLVWSKVSGYPWWPCMVSADPLLHSYTKLKGQKKS--------ARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQAPTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNP------QVAKEAGIAAESLG----EMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSS----AETLESHPDIGKSTPQK---------TAEADPRRGVGSPPGRKKTTVSMPRSRKGDAASQFLVFCQKHRDEV-VAEHPDASGEEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTEDAEAEDTPR--KRLRTDKHSLRKRDTITDKTAR--------TSSYKAMEAASSLKSQAATKNLSDA--CKPLKKRNRASTAASSALG-FSKSSSPSASLTENEVSDSPGDEPSESPYESADETQTEVSVSSKKSERGVTAKKEYVCQLCEKPGS-LLLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHSCFVCKESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCVSCHASNPSN--PRPSKGKMMRCVRCPVAYHSGDACLAAGCSVIASNSIICTAHFTARKGKRHHAHVNVSWCFVCSKGGSLLCCESCPAAFHPDCLNIEMPD-GSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAEVCHPKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKNALQEAEARFREIKLQREARETQE---SERKPPPYKHIKVNKPYGKVQIYTADISEIPKCNCKPTDENPCGFDSECLNRMLMFECHPQVCPAGEFCQNQCFTKRQYPETKIIKTDGKGWGLVAKRDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTIDKDRIIDAGPKGNYSRFMNHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGNE-KTVCRCGASNCSGFLGDRPKTSTTLSSEEKGKKTKKKTRRRRAKGEGKRQSEDECFRCGDGGQLVLCDRKFCTKAYHLSCLGLGKRPFGKWECPWHHCDVCGKPSTSFCHLCPNSFCKEHQDGTAFSCTPDGRSYCCEHDLGAASVRSTKTEKPPPEPGKPKGKRRRRRGWRRVTEGK--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B8JIA4-1", "uniprot_id": "B8JIA4_DANRE", "id": "B8JIA4-1", "name": "", "aln": "------------------------------------------------------------------------------------MTDSKGGSLPAMPEPKSPTSMKQLSDSPGGRNGLVDG-ITDPTMLMNKAATQLAATPQES-----VPQMIGSHGHN--HTHEHLKDLTSRLLNG-----DTEKIPKLCAAPAGQPLLKGVEPVSQHASPPRKTSVSPELTVKITKCVVNLGGKPNRYEVDYTEEKAEETDAPLRLPEGVLTSPTARRDRQKKKGMVRKRIPPYPILTHAASSDQSPLLHPTINSNDITIEPCGLPVESIEHTHG-------------DMPTCVTAFPDEQPLSDCEETVDAQGVDETDDAQGENDVKESYTETQSNVHFSVGDVIWTKVSGYPWWPCMITTDPEFNMHFRSKVNSRT--------GLLYHVQYFGDTPERGYVFEKCIVTFSGKHQYQSLSRS--NQLPINISGRK--RAVPRKFRQKWEIGVSQAKEALGLLTEERLAKFSFVYEDGKAQLNPHMLQVLEEQRNQGLQEEPVQREPQELVSLTPPDSTHSSPTNSSTTSTIPSLFSNPIDSSTSSGKTALPRKARKPSVKTNRRKQRSSTIEWIVTEASSAKQMPLTESTVQCEVNTEHKKKGKTNAGKRPYRKKDLLCIDLDLQPKASQKKPRHIRQKFPAAPNSVKKRKIKAGVSICDTLNTVSTSAGLSEVKASAPSTKLWEKEDASSKGMKKVCKRSRESKQDVTLQPKKKSKLEKDFKKWKCPKAASSAPAAVPAPRGRRRKTDRDEN--RKRSKKASKEEPPPKAKRGRKRKEESGRQSFPASKKCRPSSYAEPERPDSPSDS--TDESHPSKKAERTPGAKKESVCLVCEQTGEDIVTCAGQCYGTYHLHCIGVERSAE-KILCTACSTGVHVCFTCKKSEGEVRRCCALHCGRFYHEACVRLSALTVFENRGFRCPLHTCLSCHYSGRAA--CKATKGKMMRCLRCPVAYHVGDLCVAAGSEMISSSAIVCTNHFRAKKGYSHHSHVNVSWCFICSKGGRLLCCESCPAAFHPDCLNIAMPD-GSWFCNDCRSGKKPKYRDVIWVKLGNYRWWPAEIRHPKNIPTNIQHLRHEIGEFPVFFFGSKDYFWTHQGRVFPYMEGDRGSKYQQT-GIGKVFKNALLDAETRFKEIEMEREAKEAHE---NNKKPPPFKYIKVNKPCGRVQVYTADISEIPKCNCKPSTERPCSFESECLNRMLLYECHPQVCPAGERCQNQDFTKRLYPETKIIRTAGKGWGLISLRDIKKGEFVNEYVGELIDEEECRSRIRHAQENDITHFYMLTIDKDRIIDAGPKGNYSRFMNHSCQPNCETQKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGNE-KTVCRCGAPNCSGFLGDRPKN--GHTSEPKAKLQKKKPKRKRARNEGKK-SEDECFRCGDGGQLVLCDKKGCTKAYHLSCLDRTKRPFGRWDCPWHHCDVCGKNSAAFCQLCPNSFCKAHQEGALRSHPLTGQLCCQEHEDSDIRPQTETAQLPPPTKPRKYRRRAEAKTTSKAPLKKRPRKNAEV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8MT36-1", "uniprot_id": "NSD_DROME", "id": "Q8MT36-1", "name": "Nuclear receptor binding SET domain protein", "aln": "MKLSTDAHSEIEGDAAHGNVLCNSASDSLTATDEVAAGNDESVATEGDDVEIPRDTNNSTPVRLLDKPGQNPVQNGAQPAAEESELESQRQTPVQKQQQQRVSMVNRKRDLINLQSALSPKYIGYANANSPTPLSDSDDTIRTTRRRVNQAAALNNSSAGETLAHDNASPRTPGGGGGGGGDDSANQLLSKTYMSPIEKLLIKNGASSPNSTGFEAGSEDLGIRPIVRKHVKRKMKRVPKAKVTLELDEKNQQEVDEKSVKTEPIDEEVDRTDEAPTQEAQTTAISIKSETEAEHKAAVDVHIKQEDTIRLDIVNNPVESTSIVITEEPKDLEKSTEELAFALPLASSTEVDLKSPPDLSSTALATSIKSPSSVSIDSAKGLSIVTDPGWPTYQVGDLFWGKVFSYCFWPCMVCPDPLGQIVGNMPSHPQRSSLDNANVPIQVHVRFFADNGRRNWIKPENLLTFAGLKAFDDMREELRIKHGPKSAKYRQMVPKR-TKVVIWRQAIEEAQAMTQIPYSDRLEKFYQTYEN-VVTLNR------QKRKRTKYMMQDTS-------DVGSSLYDSTDNLHNKQGTQLLAVKRERSESPFSPAFSPVKSKNEKRAKRRKLSNG--------TEADTGSNSMAVTPSQTETTVDSSAYENPEFRQLLSAVMEYVMMNRSDEKVEKVLLSVVSNIWSLKQIQLRELERDLASGEIEEPLGSSVVGRGSGVGTIKRLSNRLMTMMVRRSMTPVVTPSTTPAPSEPDRRLSEPPKTKKPVN--------RPIEEVIEDILQLDSKYLFRGLSREPICKYCYQAGSDLVRCSRTCSSWLHADCLERKVTGAPMPKIGSRKALVIP-PTSKSPSPDEDHVTADAKEVVAVGTSLVCHECNVGEP------EGCVICHQVESPAVPSTPRKEDSSSHTP-----------IEDKLLTCSQPMCGKRFHTSCCKYWPQASSSKHSARCPRHVCHTCVSDDPSGKFQQLGSSKLAKCVRCPATYHQLSKCIPAGTQMLNTTNIICPRHNIAKAD----AHVNVLWCYICVKGGELVCCETCPIAVHAHCRNIPIKTNESYICEECESGRLPLYGEIVWAKFNNFRWWPAIILPPTEVPSNILKKAHGENDFVVRFFGTHDHGWISRRRVYLYIEGDTGDGHKTKSQLFRNYTTGVEEASRFLPIIKARRQEQDMERQSGNKLHPPPYVKIKTNKAVPPLR-FSQNLEDLSTCNCLPVDEHPCGPEAGCLNRMLFNECNPEYCKAGSLCENRMFEQRKSPRLEVVYMNERGFGLVNREPIAVGDFVIEYVGEVINHAEFQRRMEQKQRDRDENYYFLGVEKDFIIDAGPKGNLARFMNHSCEPNCETQKWTVNCIHRVGIFAIKDIPVNSELTFNYLWDDLMNNSKKACFCGAKRCSGEIGGKLKDDAVKAHAKLKQMRRAKASAVRIHVKPKKTPKVKHISADDEPMDAKDE----------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : . ::: : . .. . :: : : :.. . . :: . *. .* .. . : : . ::: . . : : * . : : : : . . : : :. . .: : . ..: . . :.***:.* ** .* :****: .** : . : : **::*.* .* :: : :::* * ::.: .. : : : . *. .: :*: : .:* ** * . ** : :. : . : . : . . * . : : . : . : . . . . .: . : .. . .: . :: . . . ... . * . . . . . ..* . . .. .: . . * : . . . : .. ... . * .:.. .: . : .::. . .. ** *: * .:: . .: .. . .: . : .: * **: :* :* : . : ..:. *** * * :* .. : : .. * *:***:** *.*..* .* : *::*::*.:*: : :::*.*:.*:***** : *.::*.** : * .:* * ***::*: * : **: *:*** *. :: : : :...: :*. : :: .*: :: .. .: :***: **.**. :: :: ::.::..*** * *.**. :: ******: **:*: * **. *:*: * :* *. ::: :*:**: . * *:** *****:*:. * *:. :.: ::*:* ::** ********* :*******:***** ***** ***:**: ***..:****** * * *: *..* *** .*** :*.: * : : : *. * : : *: .: : : ..* . : ", "identical_positions": 203, "similar_positions": 349, "identity": "12.7%" }, { "cls_id": "homologset.agr.MGI:1276575", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5PQL5-1", "uniprot_id": "PTSS1_RAT", "id": "Q5PQL5-1", "name": "Phosphatidylserine synthase 1", "aln": "---------------------------------------MASCVGSRTLSKDDVN---------------YRMHFRMINEQQVEDITIDFFYRPHTITLLSFTIISLMYFAFTRDDCVPEDNIWRGILSVIFFFLIISVLAFPNGPFTRPHPALWRMVFGLSVLYFLFLVFLLFLNFEQVKSLMYWLDPNLRYATREADIMEYAVNCHVITWERIVSHFDIFAFGHFWGWAMKALLIRSYGLCWTISITWELTELFFMHLLPNFAECWWDQVILDILLCNGGGIWLGMVVCRFLEMRTYHWASFKDIHTTTGKIKRAVLQFTPASWTYVRWFDPKSSFQRVAGIYLFMIIWQLTELNTFFLKHIFVFQASHPLSWCRILFIGCITAPTVRQYYAYLTDTQCKRVGTQCWVFGVIGFLEAIVCIKFGQDLFSKTQILYVVLWLLCVAFTTFLCLYGMVWYAEHYGHREKTYSECEDGTYSPEISWYHGKGSKGSEDSPPKHSNNNESHSSRRRNRHSKSKVTNGVGKK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99LH2-1", "uniprot_id": "PTSS1_MOUSE", "id": "Q99LH2-1", "name": "Phosphatidylserine synthase 1", "aln": "---------------------------------------MASCVGSRTLSKDDVN---------------YRMHFRMINEQQVEDITIDFFYRPHTITLLSFTIISLMYFAFTRDDSVPEDNIWRGILSVIFFFLIISVLAFPNGPFTRPHPALWRMVFGLSVLYFLFLVFLLFLNFEQVKSLMYWLDPNLRYATREADIMEYAVNCHVITWERIVSHFDIFAFGHFWGWAMKALLIRSYGLCWTISITWELTELFFMHLLPNFAECWWDQVILDILLCNGGGIWLGMVVCRFLEMRTYHWASFKDIHTTTGKIKRAVLQFTPASWTYVRWFDPKSSFQRVAGIYLFMIIWQLTELNTFFLKHIFVFQASHPLSWGRILFIGCITAPTVRQYYAYLTDTQCKRVGTQCWVFGVIGFLEAIVCIKFGQDLFSKTQILYVMLWLLCVAFTTFLCLYGMVWYAEHYGHREKTYSECEDGTYSPEISWHHGKGSKGSEDSPPKHSSNHESHSSRRRNRHSKSKVTNGVGKK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P48651-1", "uniprot_id": "PTSS1_HUMAN", "id": "P48651-1", "name": "Phosphatidylserine synthase 1", "aln": "---------------------------------------MASCVGSRTLSKDDVN---------------YKMHFRMINEQQVEDITIDFFYRPHTITLLSFTIVSLMYFAFTRDDSVPEDNIWRGILSVIFFFLIISVLAFPNGPFTRPHPALWRMVFGLSVLYFLFLVFLLFLNFEQVKSLMYWLDPNLRYATREADVMEYAVNCHVITWERIISHFDIFAFGHFWGWAMKALLIRSYGLCWTISITWELTELFFMHLLPNFAECWWDQVILDILLCNGGGIWLGMVVCRFLEMRTYHWASFKDIHTTTGKIKRAVLQFTPASWTYVRWFDPKSSFQRVAGVYLFMIIWQLTELNTFFLKHIFVFQASHPLSWGRILFIGGITAPTVRQYYAYLTDTQCKRVGTQCWVFGVIGFLEAIVCIKFGQDLFSKTQILYVVLWLLCVAFTTFLCLYGMIWYAEHYGHREKTYSECEDGTYSPEISWHHRKGTKGSEDSPPKHAGNNESHSSRRRNRHSKSKVTNGVGKK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q803C9-1", "uniprot_id": "PTSS1_DANRE", "id": "Q803C9-1", "name": "Phosphatidylserine synthase 1", "aln": "---------------------------------------MATTFRSQTLSKDDVN---------------YRMHFRMINEQQVEDITIQFFYKPHTISLLTVTVLSLMYFAFTRDDGDPDSNLRVGLILLVSFFLVISVLAFPNGPFTRPHPAIWRIVFGLSVLYFLFLVFIIFLNWDQVKALMFWLDPNLRYAKREADVMEYAVNCHVITWERILSHFDIFAFSHFWGWGMKALLIRSYGLCWTISITWELTELFFMHLLPNFAECWWDQVILDILLCNGGGIWLGMTVCRFLEMRTYHWASIKDIHSTTGKIKRAVLQFTPASWTYVRWLDPKSSLQRVMGVYLFMIIWQLTELNTFFLKHIFVFPACHALSWCRILFIGIITAPTVRQYYAYLTDTQCKRVGTQCWVFGAIAFLEALACIKFGQDLFSKTQILYVILWLVCLAFITFLCLYVMVWYAENYGPRQKSFSECEDSIYS-------EAGDSVTECKGEFEIDSTTSCSTRKRRDSGDSRTINGMEK--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8N7T7D0-1", "uniprot_id": "A0A8N7T7D0_DANRE", "id": "A0A8N7T7D0-1", "name": "Phosphatidylserine synthase", "aln": "---------------------------------------MAPSQGSRMLSKDDAD---------------YKLHFRMINEQQVEDITIDFFYKPHTITLLTFTVVSIMYFAFTRDDGDSDKNLRVGLLLVVSFFLVISVLAFPNGPFTRPHPSVWRMVFGLSVLYFLFLVFLIFLNWDQVKALLYWLDPNLRYAKREADVMEYAVNCHVITWERILSHFDIFALGHFWGWAMKALLIRSYGLCWTISITWELTELFFMHLLPNFAECWWDQVILDILLCNGGGIWLGMTVCRFLEMRTYRWASIKDIHSTSGKLKRAVLQFTPASWTYVRWFDPKSSFQRVAGIYLFMIVWQLTELNTFFLKHIFVFQASHPLSWCRILFIGIITAPTVRQYYAYVTDTQCKRVGTQCWVFGAIAFLEALACIKFGHDLFSNTQALYVVFWLLCLAFITFLCLYGMVWYEQNYGKKLKRIPD-DDGTST-------DPYDSLPEAAKERSSSSNSSSS--RRRKGGKHKTANGTSGKK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VPD3-1", "uniprot_id": "PTSS_DROME", "id": "Q9VPD3-1", "name": "Phosphatidylserine synthase", "aln": "MKKRTNSRGTPTSSGDALLDTSFSSAGDAERDHPAYKSGAASAPATPTKRRDGSDGSVSSAGARRKRKDEIAQTFVIVNERPVDDISLDFFYKPHTITLLAVSVLAVMYFAFVRNEANVDENLWAGLLCIVFFFLIVSVIAFPNGPFTRPHPAVWRILFGCSVLYLLTLQFLMFQNYPTIRSIFYWIDPKLKNFHIDMEK-EYGVNCSDISWDRVKGHLDVFAWGHFLGWAFKAILIRHMGILWAISVMWEITEITFAHLLPNFIECWWDALILDVIICNGLGIWMGLKICQILEMREYKWASIKDISTTTGKIKRAMLQFTPESWSAIRWLDPKSTAMRFAAVIQLVIFWQVTELNTFFLKHIFEMPPDHFIVIGRLIFIGLFVAPSVRQYYVYVTDTRCKRVGTQCWVYGAIMVSEAILCIKNGKELFERTQAINIVLWLTVQVIISVAFVYLAVYWQQRQLKKVS----------------------STPAKTKETIPASSSSPSKGKLSPQKEKKLK-------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. : :*. : * ::**: *:**:::***:****:**:.:::::*****.*:: :.*: *:: :: ***::**:************::**::** ****:* * *::* *: ::::::*:**:*: : : **.*** *:*:*: .*:*:** .** **.:**:*** *: *:**: **:**: * ****** ***** :***:::*** ***:*: :*::**** *:***:*** :*:**:***:***** **: :**:****: *. .: ::*.**:************ : . * : *::*** :.**:*****.*:***:**********:*.* . **: *** *::**..** : :::** .: :. :* ::: :. : . . . . * * : . : ", "identical_positions": 200, "similar_positions": 136, "identity": "37.88%" }, { "cls_id": "homologset.agr.MGI:1276578", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8J8XL46-1", "uniprot_id": "A0A8J8XL46_RAT", "id": "A0A8J8XL46-1", "name": "", "aln": "-------------------------------------------MPRSFLVKSKK------------------------------------------------AHTYHQP--------RAQGDDLVWPPAVIP------------VAKEHTQS--GSPVL----------------------STLLPSQTLDWSAVKQKQEMLLNQ-SLPKMASAPEGPHVTS----QPQDGESPLSESPPFYKPSFSWDTLASSYRHSYQQTPSTMQSAFLERSVR-----------------------------------------------------LYGSPLVPSTES-------------------------PLDFSLR---------------YSPGM---------------------------------------------------------------------------------------------------------------DTYHCVKCNKVFSTPHGLEVHVRRSHSGTRPFACDICGKTFGHAVSLEQHTHVHSQGVPARSSPSPSLAVPGLEAPPAPDPPRPRFLRQERSFECRMCGKAFKRSSTLSTHLLIHSDTRPYPCQFCGKRFHQKSDMKKHTYIHTGEKPHKCQVCGKAFSQSSNLITHSRKHTGFKPFSCELCTKGFQRKVDLRRHRESQHN-LK-----------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70237-1", "uniprot_id": "GFI1B_MOUSE", "id": "O70237-1", "name": "Zinc finger protein Gfi-1b", "aln": "-------------------------------------------MPRSFLVKSKK------------------------------------------------AHTYHQP--------RAQGDELVWPPAVIP------------VAKEHSQS--ASPLL----------------------STPLPSQTLDWNTIKQEREMLLNQ-SLPKMASAPEGPLVTP----QPQDGESPLSESPPFYKPSFSWDTLASSYSHSYTQTPSTMQSAFLERSVR-----------------------------------------------------LYGSPLVPSTES-------------------------PLDFRLR---------------YSPGM---------------------------------------------------------------------------------------------------------------DTYHCVKCNKVFSTPHGLEVHVRRSHSGTRPFACDVCGKTFGHAVSLEQHTHVHSQ---------------------------------ERSFECRMCGKAFKRSSTLSTHLLIHSDTRPYPCQFCGKRFHQKSDMKKHTYIHTGEKPHKCQVCGKAFSQSSNLITHSRKHTGFKPFSCELCTKGFQRKVDLRRHRESQHN-LK-----------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5VTD9-1", "uniprot_id": "GFI1B_HUMAN", "id": "Q5VTD9-1", "name": "Zinc finger protein Gfi-1b", "aln": "-------------------------------------------MPRSFLVKSKK------------------------------------------------AHTYHQP--------RVQEDEPLWPPALTP------------VPRDQAPS--NSPVL----------------------STLFPNQCLDWTNLKREPELEQDQ-NLARMAPAPEGPIVLS----RPQDGDSPLSDSPPFYKPSFSWDTLATTYGHSYRQAPSTMQSAFLEHSVS-----------------------------------------------------LYGSPLVPSTEP-------------------------ALDFSLR---------------YSPGM---------------------------------------------------------------------------------------------------------------DAYHCVKCNKVFSTPHGLEVHVRRSHSGTRPFACDICGKTFGHAVSLEQHTHVHSQ---------------------------------ERSFECRMCGKAFKRSSTLSTHLLIHSDTRPYPCQFCGKRFHQKSDMKKHTYIHTGEKPHKCQVCGKAFSQSSNLITHSRKHTGFKPFSCELCTKGFQRKVDLRRHRESQHN-LK-----------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FBX7-1", "uniprot_id": "E7FBX7_DANRE", "id": "E7FBX7-1", "name": "", "aln": "-------------------------------------------MPRSFLVKSKK------------------------------------------------SYNVHRPNDTEQAPQKLPEPEPKTIPALVP------------LEPKECKSPERPQVD----------------------PVTRPSHRDPYDFIKCEREPDCPIPSLPELPTATRRPFYIS----EPQ-----LAEFPPYYKSSFGWDHGPASY-QEFRHMG--FSPSLLHHASS-----------------------------------------------------LYGAHLKQSAEPQ------------------------PLDCSTH---------------YSPSS---------------------------------------------------------------------------------------------------------------NTYHCITCDKVFSTPHGLEVHVRRSHSGTRPFECSICRKSFGHAVSLEQHMNVHSQ---------------------------------ERSFECKMCGKTFKRSSTLSTHLLIHSDTRPYPCQYCGKRFHQKSDMKKHTYIHTGEKPHKCQVCGKAFSQSSNLITHSRKHTGFKPFGCEICSKGFQRKVDLRRHHESQHS-LK-----------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VM77-1", "uniprot_id": "Q9VM77_DROME", "id": "Q9VM77-1", "name": "", "aln": "MDVAKMQATSGQHLLHPAAPPAHQHHLPLDYSLGNFKPAIASDFPGPFLTSQQSSSASNSASSSAAATVPLQVRDLSALTAMATIPSPTQLLHQRIQMSADAALGHHQQQPAQNPNPNPNHPQPQMPPASTSPHEYAPMSAFKAVLPKKRNSDDASLAFSISRLVKTEQLTAMAAAVGLKPPTPLEDNNNSISMLSKNQQMHQQHHQQSHLAQRPKPAFISASEKLRRQSRSRSRSRSRSPCSSQIDMEDADSNHSHRSLHSRSRSRSRSRSHSRSRSHSSSSSVELEVDSPPGSPRISSPSGASASASELLITANGGGRSIGSKKSDLFSVSALLRRDEPPPQRRTPRSPPLGHLTSSGLAMPFNPLEAMRQGYPPNYDAAMFQRPLFSPALPFFAAVAFHQGQQQQQQQQQQQSGLAAGYHPDSQENLFRLRSLMVPLQSAGQNNSSAAAAAAAAAAAAVGVGVGVGVGVPPNGGHLGLPHSPHLHHFHHMAAKWPGLHQFSDLYSCMKCEKMFSTPHGLEVHSRRTHHGKKPYACELCNKTFGHEVSLSQHRAVHNV---------------------------------EKVFECKQCGKRFKRSSTLSTHLLIHSDTRPYPCNYCGKRFHQKSDMKKHTYIHTGEKPHKCQVCGKAFSQSSNLITHSRKHTGYKPFSCKLCHKAFQRKVDLRRHKETQHTDLRVHLGKVDFMSAAAAAAASAELSAAAAAAAAAGGSVPGGGPPGSQGANAVGSAPNGAPPMGGLNCQKVSLLA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* .**...:. : *: . : ** . : .. * . .. .: :. : : . ..:. .. . . . * : . ...:. : :.: : : . :: : : * *. .*: : :**. : * *:.*:*:********** **:* *.:*: *.:* *:*** ***.** **. *: ***: *** **********************::************************************************:***.*::* *.**********:*:**. *: ", "identical_positions": 142, "similar_positions": 85, "identity": "18.23%" }, { "cls_id": "homologset.agr.MGI:1277096", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63739-1", "uniprot_id": "TP4A1_MOUSE", "id": "Q63739-1", "name": "Protein tyrosine phosphatase type IVA 1", "aln": "-----------MARMN--RPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEKEGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIEGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNNCCIQ-------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q78EG7-1", "uniprot_id": "TP4A1_RAT", "id": "Q78EG7-1", "name": "Protein tyrosine phosphatase type IVA 1", "aln": "-----------MARMN--RPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEKEGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIEGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNNCCIQ-------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q93096-1", "uniprot_id": "TP4A1_HUMAN", "id": "Q93096-1", "name": "Protein tyrosine phosphatase type IVA 1", "aln": "-----------MARMN--RPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEKEGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIEGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNNCCIQ-------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6B5G4-1", "uniprot_id": "A0A8I6B5G4_RAT", "id": "A0A8I6B5G4-1", "name": "protein-tyrosine-phosphatase", "aln": "-----------MARMN--CPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCKATHDTTLVEKESIHVLEWHFDDGAPPSNQIVDDWLSLVKIKFPEEPGCRIAVRCVAGLGRAPGLVALALIEGGMNYEDAVQFIRQKRRGAFNGQQRLPLEKYHPKMWLRFKDSNSHRNNCCIQ-------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0AC58GQE0-1", "uniprot_id": "A0AC58GQE0_DANRE", "id": "A0AC58GQE0-1", "name": "", "aln": "MGFSSSIAKSKMARMN--RPAPVEITYKNMRFLITHNPTNATLHKFIEELKKYGVTTVVRVCEATYDANLVVKEGIQVLDWPFDDGAPPSNQIVDDWLNLLRVKFREEPGCCIAVHCVAGLGRAPVLVALALIECGMKYEDAVQFIRQKRRGAFNSKQLFYLEKYRPKMRLRFKDSNGHRTNCCIHVPFPPLHFCISCGEPLSASRKTPSGGGVLNGIWRGFLMSFAEKKIGRDSEEKSRKKKCLYTKISKVGVLVFVVYPNFVYLLLPCQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O61722-1", "uniprot_id": "PRL1_DROME", "id": "O61722-1", "name": "PRL-1 phosphatase", "aln": "--------MSITMRQKDLRPAPALIEYKGMKFLITDRPSDITINHYIMELKKNNVNTVVRVCEPSYNTDELETQGITVKDLAFEDGTFPPQQVVDEWFEVLKDKYQQNPEACVAVHCVAGLGRAPVLVALALIELGLKYEAAVEMIRDKRRGAINAKQLSFLEKYKPKARLKHK--NGHKNSCSVQ-------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : ***. : **.*:****..*:: *::::* **** .*.*:****:.:::: : .:.* * : *:**: *.:*:**:*:.::: *: ::* . :**:********* ******** *::** **::**:*****:*.:* ****:** *:.* *.*:..*.:: ", "identical_positions": 80, "similar_positions": 62, "identity": "29.52%" }, { "cls_id": "homologset.agr.MGI:1277097", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LN97-1", "uniprot_id": "F1LN97_RAT", "id": "F1LN97-1", "name": "", "aln": "-MDPERCAPFA-----VGPAAGPYAAARDEAPGPQGTPDAAPHLRPAPPRGPRLSRFPACGPLEPYLPEPAKPP-------AKYLQDLG----PGPVLNGGHFYKGSSEAEEKA-SKAASFPQLPVDCRGGPRDGPSNVQGSPGPCLASLSVPLSPGLPDSMELAKSKSKK--RRNRTTFSTFQLEELEKVFQKTHYPDVYAREQLALRTDLTEARVQVWFQNRRAKWRKRERYGKIQ--------EGRNPFTTAYDISVLPRTDSHPQLQNSLWSS----PGSGSPGGPCLMPPEGIPSPCMSPYSHS----HGNVAGFMGVPASP-------------AAHP---GIYSIHGFPPALGGHSFEPSPDGDYKSPSLVSLRMKPKEPP-------------SLLNWTT-------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70137-1", "uniprot_id": "ALX3_MOUSE", "id": "O70137-1", "name": "Homeobox protein aristaless-like 3", "aln": "-MDPERCAPFS-----VGPAAGPYAAAGDEAPGPQGTPDAAPHLHPAPPRGPRLSRFPACGPLEPYLPEPAKPP-------AKYLQDLG----PGPVLNGGHFYEGSAEAEEKA-SKAASFPQLPVDCRGGPRDGPSNVQASPGPCLASLSVPLSPGLPDSMELAKTKSKK--RRNRTTFSTFQLEELEKVFQKTHYPDVYAREQLALRTDLTEARVQVWFQNRRAKWRKRERYGKMQ--------EGRNPFTTAYDISVLPRTDSHPQLQNSLWPS----PGSGSPGGPCLMSPEGIPSPCMSPYSHS----HGNVAGFMGVPASP-------------AAHP---GIYSIHGFPPALGGHSFEPSPDGDYKSPSLVSLRMKPKEPP-------------GLLNWTT-------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95076-1", "uniprot_id": "ALX3_HUMAN", "id": "O95076-1", "name": "Homeobox protein aristaless-like 3", "aln": "-MDPEHCAPFR-----VGPAPGPYVASGDEPPGPQGTPAAAPHLHPAPPRGPRLTRFPACGPLEPYLPEPAKPP-------AKYLQDLG----PGPALNGGHFYEGPAEAEEKT-SKAASFPQLPLDCRGGPRDGPSNLQGSPGPCLASLHLPLSPGLPDSMELAKNKSKK--RRNRTTFSTFQLEELEKVFQKTHYPDVYAREQLALRTDLTEARVQVWFQNRRAKWRKRERYGKIQ--------EGRNPFTAAYDISVLPRTDSHPQLQNSLWAS----PGSGSPGGPCLVSPEGIPSPCMSPYSHP----HGSVAGFMGVPAPS-------------AAHP---GIYSIHGFPPTLGGHSFEPSSDGDYKSPSLVSLRVKPKEPP-------------GLLNWTT-------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PL59-1", "uniprot_id": "A0A8M9PL59_DANRE", "id": "A0A8M9PL59-1", "name": "", "aln": "-METESSLSFSSPPNRITPDNSPGLEHNSSSFFQCDDLQKSPHLALAHRHEFFMGRYADGGSADFTHGVSSTTPRASPGKHTKYLENINQDQKPSITEKNSSFYETNSDAGDKTLSKPLGYPALDSECCGKLKEASNGLTGDS--------------IADSIDLS-GKNKK--RRNRTTFSTFQLEELEKVFQKTHYPDVYAREQLALRTELTEARVQVWFQNRRAKWRKRERYGKMQ--------EVRNHFAATYDISLLPRSDTY-QMQNSLWPSGAGATGAGGASSACVLGTENMPSSCMSPYPHP----HGNLPGLMGMSASPGHHHHHHHHHHHPSHHPSINGIYSLHGFPGSLGAHTFEAGPESEYKPSGLVALRMKTKDPG-------------SLLSWPT-------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W2P8-1", "uniprot_id": "Q9W2P8_DROME", "id": "Q9W2P8-1", "name": "", "aln": "MMTTTTSQHHQ-----HHPIMPPAMRPAPVQESPVSRPRAVYSIDQILGNQHQIKRSDTPSEVLITHPHHGHPH---------HIHHLHS---SNSNGSNHLSHQQQQQHSQQQHHSQQQQQQQQLQVQAKREDSPTNTDGGLDVDNDD---ELSSSLNNGHDLSDMERPRKVRRSRTTFTTFQLHQLERAFEKTQYPDVFTREDLAMRLDLSEARVQVWFQNRRAKWRKREKFMNQDKAGYLLPEQGLPEFPLGIPLPPHGLPGHPGSMQSEFWPPHFALHQHFNPAAAAAAG--LLPQHLMAPHYKLP-NFHTLLSQYMGLSNLNG-IFGAGAAAAAAAASAGYPQNLSLHAGLSAMSQVSPPCSNSSPRESPKLVPHPTPPHATPPAGGNGGGGLLTGGLISTAAQSPNSAAGASSNASTPVSVVTKGED", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9XZU0-1", "uniprot_id": "Q9XZU0_DROME", "id": "Q9XZU0-1", "name": "", "aln": "-MDKGTMKRKQ------RRYRTTFNTLQLQELERAFQRTHYPDVFFREELAVRIDLTEARVQVWFQNRRAKWRK-------QEKIGGLGG-DYKEGALDLDVSYDDSAVLGQLDSALGGGGTLLPDTPPQSSNSLDNELKASYGTGAMS-----PSRLSPNIFLNLNIDHLGLERGGSGLS-MEWSTYPPQTQAQTHPQMDSDNQLQQHPPQQHASDPIHAGSSSHHQQQQQQHQQEQHN-----PQLHPGLEFAASLSLDMTDGSSAYDEMKFLSVDVDQFTIDSFKADCILSMEQSQMQAYGGHSQLVGSSNELCLDGIGMSSFG-------------MEEGEPKSPPSLLVLDKSLPSLSIGVEGIADLVEQLHHHQHEGGPVGG-------------GVITGDVM------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . : : : : . :. : .. . .. : . * .*. : :: :: : :*:: : ::* : .* : . : :::::. : : : : :. . : .: . . . . . : : : :*:. *: :: : . .::. . ", "identical_positions": 8, "similar_positions": 72, "identity": "1.85%" }, { "cls_id": "homologset.agr.MGI:1277098", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B0K032-1", "uniprot_id": "B0K032_RAT", "id": "B0K032-1", "name": "Protein tyrosine phosphatase type IVA 3", "aln": "---MARMN--RPAPVEVSYRHMRFLITHNPSNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLLKAKFYNDPGSCVAVHCVAGLGRAPVLVALALIESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCVM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D658-1", "uniprot_id": "TP4A3_MOUSE", "id": "Q9D658-1", "name": "Protein tyrosine phosphatase type IVA 3", "aln": "---MARMN--RPAPVEVSYRHMRFLITHNPSNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLLKAKFYNDPGSCVAVHCVAGLGRAPVLVALALIESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCVM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75365-1", "uniprot_id": "TP4A3_HUMAN", "id": "O75365-1", "name": "Protein tyrosine phosphatase type IVA 3", "aln": "---MARMN--RPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCVM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O61722-1", "uniprot_id": "PRL1_DROME", "id": "O61722-1", "name": "PRL-1 phosphatase", "aln": "MSITMRQKDLRPAPALIEYKGMKFLITDRPSDITINHYIMELKKNNVNTVVRVCEPSYNTDELETQGITVKDLAFEDGTFPPQQVVDEWFEVLKDKYQQNPEACVAVHCVAGLGRAPVLVALALIELGLKYEAAVEMIRDKRRGAINAKQLSFLEKYKPKARLKHKN--GHKNSCSVQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : ****. :.*: *:****..*:: *:. :* :*** ...******* :*:. **.:**** * .*:**: ** :**::*:.::* *: : * :*********************** *:*** *:::**:*******:***::****:** **:.*: **. *.* ", "identical_positions": 96, "similar_positions": 49, "identity": "53.93%" }, { "cls_id": "homologset.agr.MGI:1277101", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D3J5-1", "uniprot_id": "ANR22_MOUSE", "id": "Q9D3J5-1", "name": "Ankyrin repeat domain-containing protein 22", "aln": "-------------MGILYS---------------EPICQAAYQNDLGQVWRWAKESNHYVDVQDSFNGDTPLICACRRGHLRIVSFLLRRNADVNLKNLKERTCLHYAVKKRFTFFDYLLIILLMPVLLIGYFLMVSKTKQNETLVRMLLNAGVEVNATDCDGYTALHYACQMKNQTLIPLLLEAHADPMIKNKHGESSLDIAQRLKFSQIALMLKRAS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6A2D2-1", "uniprot_id": "A0A8I6A2D2_RAT", "id": "A0A8I6A2D2-1", "name": "", "aln": "ESEDWNTGSSHVKLVLLITRKHHFPPKGAESWPDPPICQAAYQNDLGQVWRWVKESNHYVDIQDGFNGDTPLICACRRGHLRIVSFLLRRNADVNLKNLKERTCLHYAVKKRFTFFDYLLIILLMPVLLIGYFLMVSKTKQNEALVRMLLNAGVEVNATDCYGYTALHYACQMKNQTLIPLLLAARADPTIKNKHGESSLDIAQRLKFNQIALMLKKGS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5VYY1-1", "uniprot_id": "ANR22_HUMAN", "id": "Q5VYY1-1", "name": "Ankyrin repeat domain-containing protein 22", "aln": "-------------MGILYS---------------EPICQAAYQNDFGQVWRWVKEDSSYANVQDGFNGDTPLICACRRGHVRIVSFLLRRNANVNLKNQKERTCLHYAVKKKFTFIDYLLIILLMPVLLIGYFLMVSKTKQNEALVRMLLDAGVEVNATDCYGCTALHYACEMKNQSLIPLLLEARADPTIKNKHGESSLDIARRLKFSQIELMLRKAL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :* : **********:******.**.. *.::**.***************:***********:***** ************:***:***************************:******:********** * *******:****:****** *:*** *************:****.** ***::. ", "identical_positions": 155, "similar_positions": 25, "identity": "70.78%" }, { "cls_id": "homologset.agr.MGI:1277103", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CQ48-1", "uniprot_id": "NUDC2_MOUSE", "id": "Q9CQ48-1", "name": "NudC domain-containing protein 2", "aln": "MSAPFEERSGVVPCGTPWGQWYQTLEEVFIEVQVPPGTRAQDIQCGLQSRHVALAVGGREILKGKLFDSTIADEGTWTLEDRKMVRIVLTKTKRDAANCWTSLLESEYAADPWVQDQMQRKLTLERFQKENPGFDFSGAEISGNYTKGGPDFSNLEK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5M823-1", "uniprot_id": "NUDC2_RAT", "id": "Q5M823-1", "name": "NudC domain-containing protein 2", "aln": "MSAPFEERSGVVPCATPWGQWYQTLEEVFIEVQVPPGTRAQDIQCGLQSRHVALAVGGREILKGKLFDSTIADEGTWTLEDRKMVRIVLTKTKRDAANCWTSLLESEYAADPWVQDQMQRKLTLERFQKENPGFDFSGAEISGNYTKGGPDFSNLEK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8WVJ2-1", "uniprot_id": "NUDC2_HUMAN", "id": "Q8WVJ2-1", "name": "NudC domain-containing protein 2", "aln": "MSAPFEERSGVVPCGTPWGQWYQTLEEVFIEVQVPPGTRAQDIQCGLQSRHVALSVGGREILKGKLFDSTIADEGTWTLEDRKMVRIVLTKTKRDAANCWTSLLESEYAADPWVQDQMQRKLTLERFQKENPGFDFSGAEISGNYTKGGPDFSNLEK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**************.***************************************:******************************************************************************************************", "identical_positions": 155, "similar_positions": 2, "identity": "98.73%" }, { "cls_id": "homologset.agr.MGI:1277106", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88416-1", "uniprot_id": "GPR33_MOUSE", "id": "O88416-1", "name": "Probable G protein-coupled receptor 33", "aln": "MDLINSSTHVINVSTSLTNSTGVPTPAPKTIIAASLFMAFIIGVISNGLYLWMLQFKMQRTVNTLLFFHLILSYFISTLILPFMATSFLQDNHWVFGSVLCKAFNSTLSVSMFASVFFLSAISVARYYLILHPVWSQQHRTPHWASRIALQIWISATILSIPYLVFRTTHDDHKGRIKCQNNYIVSTDWESKEHQTLGQWIHAACFVGRFLLGFLLPFLVIIFCYKRVATKMKEKGLFKSSKPFKVMVTAVISFFVCWMPYHVHSGLVLTKSQ-----PLPLHLTLGLAVVTISFNTVVSPVLYLFTGENFK-VFKKSILALFNSTFSD----ISSTERTQTLNSETEI----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q49SQ1-1", "uniprot_id": "GPR33_HUMAN", "id": "Q49SQ1-1", "name": "Probable G protein-coupled receptor 33", "aln": "MDLINSTDYLINASTLVRNSTQFLAPASKMIIALSLYISSIIGTITNGLYLWVLRFKMKQTVNTLLFFHLILSYFISTMILPFMATSQLQDNHWNFGTALCKVFNGTLSLGMFTSVFFLSAIGLDRYLLTLHPVWSQQHRTPRWASSIVLGVWISAAALSIPYLIFRETHHDRKGKVTCQNNYAVSTNWESKEMQASRQWIHVACFISRFLLGFLLPFFIIIFCYERVASKVKERSLFKSSKPFKVMMTAIISFFVCWMPYHIHQGLLLTTNQ-----SLLLELTLILTVLTTSFNTIFSPTLYLFVGENFKKVFKKSILALFESTFSE----DSSVERTQT-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6YSE5-1", "uniprot_id": "A0A8M6YSE5_DANRE", "id": "A0A8M6YSE5-1", "name": "", "aln": "--MENSSFGLKNLTGNSTDKNAVEDKGFKIFLACIFFSTVSVGLIGNGLVIFLAGCRMKMTFNSIWFLNLAIADFIFILFSITNASLTLSKQHSVVKEYFLFIAT---SINLFASIWSLVVISLDRCLCTWMAVWAQNNRTLRKARIICIIIWVSSIGYILPYFTVFNITG-------------------------------TILVTYGFIVVFLIPFLIIASSYIAIGVKINRLKKRKQLRSYRLIITVILTFFICSFPHNVCWIWMVWAKNNNWTLTDQFWKLFVFTFYLMNLNSSLNPFLYVFMCDDFKKKLKQSLVLVLETAFAEDHLDIKEMRHTKMINRQNKPHLNC", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : **: : * : :.. . . * ::* :: : :* * *** ::: :*: *.*:: *::* :: ** :: *: *..:* . : . *:.:*:*:: * .*.: * .**:*::** : * * : :*:*: :**: . . . *:: **:**::* .* :. *::. *. :.:::::*.:::**:* :*::: :: .: . : : ::. .:*: ..* **:* ::** :*:*:: :::::*:: .. .:*: ", "identical_positions": 62, "similar_positions": 121, "identity": "17.56%" }, { "cls_id": "homologset.agr.MGI:1277113", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88588-1", "uniprot_id": "PACS1_RAT", "id": "O88588-1", "name": "Phosphofurin acidic cluster sorting protein 1", "aln": "MAERGGAGGGPGGAGGGSSQRGSGVAQSPQQQPPQQPSQ--PQQPTPPKLAQATSSSSSTSAAAASSSSSSTSTSMAVAVASGSAPPGGPGPGRTPAPVQMNLYATWEVDRSSSSCVPRLFSLTLKKLVMLKEMDKDLNSVVIAVKLQGSKRILRSNEIILP-----------------------------------------ASGLVETELQLTFSLQYPHFLKRDANKLQIMLQRRKRYKNRTILGYKTLAVGLINMAEVMQHPNEGALVLGLHSNVKDVSVPVAEIKIYSLSSQPIDHEGIKSKLSDRSPDIDNYSEE-EEESFSSEQEGSDDPLHGQDLFYEDEDLR----------------------------------------------------KVKKTRRKLTSTSAITRQPNIKQKFVALLKRFKVSDEVGFGLEHVSREQIREVEEDLDELYDSLEMYNPS---DSGPEMEETESILSTPKPKLKPFFEG-----------------------MSQSSSQTEIGSLNSKGSLGKDTTSPMELAALEKVKSTWIKNQDDSLTETDTLEITDQDMFGDASTS--------------------LVVPEKVKTPMKSSKADLQGSASPSKVEGTHTPRQKRS---TPLKERQLSKPLSERTNSSDSERSPDLGHSTQ--------------IPRKVVYDQLNQILVS-DAALPENVILVNTTDWQG-----QYVAELLQDQRKPVVCTCSTVEVQAVLSALLTRIQRYCNCNSSMPRPVKVAAVGSQSYLSSILRFFVKSLASKTPDWLGHMRFLIVPLG--SHPVAKYLGSVDSRYSSTFLDSAWRDLFSRSEP--------------------------PVSEPLDVVGRVMQYVNGATTTHQLPVAEAMLTCRHKFPDEDSYQKFIPFIGVVKVGLVEDSP-----------STAGDGDDSPVVSLTVPSTSPPSSSGLSRDATATPPSSPSMSSALAIVGSPNSPYG-----------------------------DVIGLQVDYW-LGHPGERRREGDK------RDASSKNTLKSVFRSVQVSRLPHAGEAQLSGTMAMTVVTKEKNKKVPTIFLSKKPREKEVDS-KSQVIEGISRLICSAKQ-QQTMLRVSIDGVEWSDIKFFQLAAQWPTHVKHFPVGLFSGSKPT-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K212-1", "uniprot_id": "PACS1_MOUSE", "id": "Q8K212-1", "name": "Phosphofurin acidic cluster sorting protein 1", "aln": "MAERGGAGGGPGGSGGGSSQRGSGVAQSPQQQPQQQPPQ--PQQPTPPKLAQATSSSSSTSAAAASSSSSSTSTSMAVAVASGSAPPGGPGPGRTPAPVQMNLYATWEVDRSSSSCVPRLFSLTLKKLVMLKEMDKDLNSVVIAVKLQGSKRILRSNEIILP-----------------------------------------ASGLVETELQLTFSLQYPHFLKRDANKLQIMLQRRKRYKNRTILGYKTLAVGLINMAEVMQHPNEGALVLGLHSNVKDVSVPVAEIKIYSLSSQPIDHEGIKSKLSDRSPDIDNYSEE-EEESFSSEQEGSDDPLHGQDLFYEDEDLR----------------------------------------------------KVKKTRRKLTSTSAITRQPNIKQKFVALLKRFKVSDEVGFGLEHVSREQIREVEEDLDELYDSLEMYNPS---DSGPEMEETESILSTPKPKLKPFFEG-----------------------MSQSSSQTEIGSLNSKGSLGKDTTSPMELAALEKVKSTWIKNQDDSLTETDTLEITDQDMFGDVSTS--------------------LVVPEKVKTPMKSSKADLQGSASPSKVEGTHTPRQKRS---TPLKERQLSKPLSERTNSSDSERSPDLGHSTQ--------------IPRKVVYDQLNQILVS-DAALPENVILVNTTDWQG-----QYVAELLQDQRKPVVCTCSTVEVQAVLSALLTRIQRYCNCNSSMPRPVKVAAVGSQSYLSSILRFFVKSLASKTPDWLGYMRFLIIPLG--SHPVAKYLGSVDSRYSSTFLDSAWRDLFSRSEP--------------------------PVSEPLDVVGRVMQYVNGATTTHQLPVAEAMLTCRHKFPDEDSYQKFIPFIGVVKVGLVEDSP-----------STAGDGDDSPVVSLTVPSTSPPSSSGLSRDATATPPSSPSMSSALAIVGSPNSPYG-----------------------------DVIGLQVDYW-LGHPGERRREGDK------RDASSKNTLKSVFRSVQVSRLPHAGEAQLSGTMAMTVVTKEKNKKVPTIFLSKKPREKEVDS-KSQVIEGISRLICSAKQ-QQTMLRVSIDGVEWSDIKFFQLAAQWPTHVKHFPVGLFSGSKTT-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6VY07-1", "uniprot_id": "PACS1_HUMAN", "id": "Q6VY07-1", "name": "Phosphofurin acidic cluster sorting protein 1", "aln": "MAERGGAGGGPGGAGGGSGQRGSGVAQSPQQPPPQQQQQQPPQQPTPPKLAQATSSSSSTSAAAASSSSSSTSTSMAVAVASGSAPPGGPGPGRTPAPVQMNLYATWEVDRSSSSCVPRLFSLTLKKLVMLKEMDKDLNSVVIAVKLQGSKRILRSNEIVLP-----------------------------------------ASGLVETELQLTFSLQYPHFLKRDANKLQIMLQRRKRYKNRTILGYKTLAVGLINMAEVMQHPNEGALVLGLHSNVKDVSVPVAEIKIYSLSSQPIDHEGIKSKLSDRSPDIDNYSEE-EEESFSSEQEGSDDPLHGQDLFYEDEDLR----------------------------------------------------KVKKTRRKLTSTSAITRQPNIKQKFVALLKRFKVSDEVGFGLEHVSREQIREVEEDLDELYDSLEMYNPS---DSGPEMEETESILSTPKPKLKPFFEG-----------------------MSQSSSQTEIGSLNSKGSLGKDTTSPMELAALEKIKSTWIKNQDDSLTETDTLEITDQDMFGDASTS--------------------LVVPEKVKTPMKSSKTDLQGSASPSKVEGVHTPRQKRS---TPLKERQLSKPLSERTNSSDSERSPDLGHSTQ--------------IPRKVVYDQLNQILVS-DAALPENVILVNTTDWQG-----QYVAELLQDQRKPVVCTCSTVEVQAVLSALLTRIQRYCNCNSSMPRPVKVAAVGGQSYLSSILRFFVKSLANKTSDWLGYMRFLIIPLG--SHPVAKYLGSVDSKYSSSFLDSGWRDLFSRSEP--------------------------PVSEQLDVAGRVMQYVNGAATTHQLPVAEAMLTCRHKFPDEDSYQKFIPFIGVVKVGLVEDSP-----------STAGDGDDSPVVSLTVPSTSPPSSSGLSRDATATPPSSPSMSSALAIVGSPNSPYG-----------------------------DVIGLQVDYW-LGHPGERRREGDK------RDASSKNTLKSVFRSVQVSRLPHSGEAQLSGTMAMTVVTKEKNKKVPTIFLSKKPREKEVDS-KSQVIEGISRLICSAKQ-QQTMLRVSIDGVEWSDIKFFQLAAQWPTHVKHFPVGLFSGSKAT-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VCE7-1", "uniprot_id": "Q9VCE7_DROME", "id": "Q9VCE7-1", "name": "", "aln": "MKMVDKSSKLVDKFAVISGTGGSGPGGGPLN---------------------------LQSGGGGGGSGGGGGVSGSGGISGTAGLSAGAGMTTGQKPVPMKLFAAWEVDRTPPNCIPRLCSLTITRLSILTPLPGDTTSLSLAVKMQSSKRTLRSHEIPINGLALTSSASLQGNSPMSVAGGVGGGGVGTPGSVGTGGGLGVAVPLTETELDLHFSLQYPHFIKRDGNRLVILLQRRKKYKSRTILGYKTLAEGIIRMDAVLQKSMDMIIELTASGKNGRPGTVVACLRAERVSSIPVDHDNKNNNSVLLADRVAEYSDEDEEAEFSSGEFNDEANELGLIRGYDPKDPRDYNHPAKHDMRKYRNKLQRSGIEDCALVGHHPGSIQHHHPGVVVDSDSEFEMKDKSSSRAKFSRTISLQQRNFKQKIVALLKRFKVSEELEGESGHRGTAALRG-ERDLDALFQELESLSCCEGDDSGPDMDSIS-VGSTPKPSLRPFFTNSRIMLHDNITGNGGDLSQLVGGGLGPGTGTAGNSERRSSDKSDQLTNSSYNLENNKNQKCIHLTNNNNSATTPDRGGNDSSGNEGNAGYTDGQNSDPQNSPPRDKDYLRLQQMQQQQLTPVSSVAASMGSGSVITPAQTEKRSRLFRTSSNTPANAGSGGNSVSAISASGGGKRKHTLSLSAEPRSVLEACLSPTNVEPRKLLLDQLSRVFAGEDSAIPEVVTIISPPEALGGSALLAKLVTLFANSFKPAFVPQNTAEVKAVLQALMAKIQKYCNSNAKPPHTVKVLLIGGDWLQGATLRHYVELMGVRPPDWLNHLRFYLVPVGGSCGSVARHLSQMDQAYAVMFGSDNWTQLCERAAATAAAVSAVTTVNATALTTNLADAAGVAKSDIAELVQRIQRYLLAAGPCTQIPIAEAMVNYK----DEDSCQIFVPFVSDVRIGYLDAQASLDLEENAAGSNAVGSGLGSGSASSSAIPIGSQSSPNVHGVVSGSPPQQQSLGRISPPLQTPPSSASSHRERNTSESLSTPSSVQQQSFSGALAAAEAVELQVDYWPLVRPGEGHAKESKGGLSKGSDAGGKNSIKSTFRNLQVWRLPQHAQQLGDMFNGLTVSFATKEKKQKQIMRLGKKKDKERDLEKEQCVEGVARLICSPKQSHPVPLRVYIDGTEWTGVKFFQVSSQWQTHVKNFPIALIGCTPMSCAELS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 322, "similar_positions": 346, "identity": "26.66%" }, { "cls_id": "homologset.agr.MGI:1277114", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WV91-1", "uniprot_id": "FPRP_MOUSE", "id": "Q9WV91-1", "name": "Prostaglandin F2 receptor negative regulator", "aln": "MGRPAPRPLLLALLSLAVCRGRVVRVPAGTLVRVVGTELVIPCNVSDYDGPSEQNFDWSFSSSGSSFVELASTWEVGFPAQLYRERLQRGDILLRRTANDAVELHIKNVQPSDQGHYKCSTPSTDATVQGNYEDTVQVKVLADALVVGPSSRPPPGLSLREGEPFELRCIASTTSPLHTHLALRWELH---RGPVHRSILALSHEGRFHPGPGYEQRYHSGDVRLDTVGSDAYRLSVARALSADQGSYRCVVSEWITEQGSWQEIQEKAVEVATVVIQPTALQLAVP--RTVSVTEGKDLDLSCNITTDRVDDVRPEVTWYFKKTPDTSLLASHMLARLDRDSLVHSSP--HVALSHVDTRSYHLLVRDVSKENSGYYLCLVALWAPGHNRSWHKVAEAMSAPSGVSVTWLEPEYQVYLNASKVPGFSDDPTELQCRVIDTKRLEAGVRLTVSWYYRMTRRNDDVVASELLAVMDGDWTLRYGERSKQRAQDGEFIFSKEHTDTFNFRIQRTTEEDRGNYYCVVSAWTRQRNNSWVKSKDVFSKPVNIFWASEDSVLVVKARQPKPFFAAGNTFEMTCKVSSKNIKS-PRYSVLITAEKPVGDLSSPNETKYIISLDQDSVVKLENWTDASRVDGVVLEKVQEDEFRYRMYQTQVSDAGLYRCMVTAWSPIGGSLWREAATSLSNPIEIDFQTSGPTFNASVHSDTPSVTRGDLIKLFCIVTVEGAVLDPDDMAFDVSWFAVHSFGLDKAPVLLSSLDRKGVVTTGQRDWKSTVSLERVSVLEFLLQVHGSEDQDFGNYYCSVTPWVRSPT-GSWQREAEIHSRPIFITVKMDVLNAFKYPLLIGVGLSTVIGLLSCLIGYCSSHWCCKKEVRETRRERRRLMSMEMD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q62786-1", "uniprot_id": "FPRP_RAT", "id": "Q62786-1", "name": "Prostaglandin F2 receptor negative regulator", "aln": "MGRPAPRPLLLALLSLAVCRGRVVRVPAGTLVRVVGTELVIPCNVSDYDGPSEQNFDWSFSSSGSSFVELASTWEVGFPAQQYRERLQRGDILLRRTANDAVELHIKNVQPSDQGHYKCSTPSTDATVQGNYEDTMQVKVLADALVVGPSSRPPPGLSLREGEPFELRCIASTTSPLHTHLALRWELH---RGPVHRSILALSHEGRFHPGPGYEQRYHSGDVRLDTVGSDAYRLSVARALSADQGSYRCVVSEWITEQGSWQEIQEKAVEVATVVIQPTALQLAVP--RTVSVTEGKDLDLSCNITTDRVDDVRPEVTWYFKKTPDTSLLASHMLARLDRDSLVHSSP--HVALSHVDTRSYHLLVRDVSKENSGYYLCLVALWAPGHNRSWHKVAEAMSAPSGVSVTWLEPEYQVYLNASKVPGFSDDPTELQCRVIDTKRVDAGVRLTVSWYYRMNRRNDDVVASELLAVMDGDWTLRYGERSKQRAQDGEFIFSKEHTDTFSFRIQRTTEEDRGSYYCVVSAWTRQRNSSWVKSKDVFSKPVNIFWASEDSVLVVKARQPKPFFAAGNTFEMTCKVSSKNIKS-PRYSVLITAEKPVGDLSSPNETKYIISLDQDSVVKLENWTDASRVDGVVLEKVQEDEFRYRMYQTQVSDAGLYRCMVTAWSPIGGSLWREAATSLSNPIEIDFQTSGPIFNASVHSDTLSVTRGDLIKLFCIVTVDGAVLDPDDMAFDVSWFAVHSFGLDKAPILLSSLDRKGVVTTGQRDWKSTVSLERVSVLEFLLQVHSSEDQDFGNYYCSVTPWVRSPT-GSWQREAEIHSRPIFITVKMDVLNAFKYPLLIGVGLSTVIGLLSCLIGYCSSHWCCKKEVRETRRERRRLMSMEMD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9P2B2-1", "uniprot_id": "FPRP_HUMAN", "id": "Q9P2B2-1", "name": "Prostaglandin F2 receptor negative regulator", "aln": "MGRLASRPLLLALLSLALCRGRVVRVPTATLVRVVGTELVIPCNVSDYDGPSEQNFDWSFSSLGSSFVELASTWEVGFPAQLYQERLQRGEILLRRTANDAVELHIKNVQPSDQGHYKCSTPSTDATVQGNYEDTVQVKVLADSLHVGPSARPPPSLSLREGEPFELRCTAASASPLHTHLALLWEVH---RGPARRSVLALTHEGRFHPGLGYEQRYHSGDVRLDTVGSDAYRLSVSRALSADQGSYRCIVSEWIAEQGNWQEIQEKAVEVATVVIQPSVLRAAVP--KNVSVAEGKELDLTCNITTDRADDVRPEVTWSFSRMPDSTLPGSRVLARLDRDSLVHSSP--HVALSHVDARSYHLLVRDVSKENSGYYYCHVSLWAPGHNRSWHKVAEAVSSPAGVGVTWLEPDYQVYLNASKVPGFADDPTELACRVVDTKSGEANVRFTVSWYYRMNRRSDNVVTSELLAVMDGDWTLKYGERSKQRAQDGDFIFSKEHTDTFNFRIQRTTEEDRGNYYCVVSAWTKQRNNSWVKSKDVFSKPVNIFWALEDSVLVVKARQPKPFFAAGNTFEMTCKVSSKNIKS-PRYSVLIMAEKPVGDLSSPNETKYIISLDQDSVVKLENWTDASRVDGVVLEKVQEDEFRYRMYQTQVSDAGLYRCMVTAWSPVRGSLWREAATSLSNPIEIDFQTSGPIFNASVHSDTPSVIRGDLIKLFCIITVEGAALDPDDMAFDVSWFAVHSFGLDKAPVLLSSLDRKGIVTTSRRDWKSDLSLERVSVLEFLLQVHGSEDQDFGNYYCSVTPWVKSPT-GSWQKEAEIHSKPVFITVKMDVLNAFKYPLLIGVGLSTVIGLLSCLIGYCSSHWCCKKEVQETRRERRRLMSMEMD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B654-1", "uniprot_id": "A0ACD6B654_DANRE", "id": "A0ACD6B654-1", "name": "", "aln": "MDEALLR-AVLLFIGLALSEGRVVKVPAGPLVHVEGQPVSIRCDVSNYEGPRDQDFEWYLMM-ADKMLPLVSTFDGSFTDASMKDRVNSRDISFVKLNDAAVELKFKSVRATDSGVYRCSTPSTDSVISGNYNADVELKVIGDSLKVSPL---IPKAAVSAGESVELQCNTTRSFTEHTFLSVSWSVGRANSSGVLEQILTFGPDDKIQTGSNYTQRYADGGLQLDLRGGGFYGLVLKATTPADRGKYVCTAQEWVRQGRTWRKILERSEDMGKVEVT-----------------------------------------------------------------------------------------------------------------------------------ATDLQYTVSLAVSVSPQSAGEPTELRCQVQQLLYLQNG-RLGVSWVYSTRGGAAEVQAEVMVATLDQQGALTAGAQYQQRLDRGDIALTRTPDNTFMLRILQTADADMGWYSCRVTAWTPDRKGVWTNSKEVQSSPVAVQWTPKTPVLSVAAHRVREASSAGSTFEMTCQVSGQNLQD-SSYSVLIRFEESGAGGKS----RKVLSLSPDSVLQLEEWSEPGRIDSVVLEKSGPAEYRFRLYGAQVSDRGFYCCDVTAWTRHQSQDWTKIISAESNKIQVDFVHTGPVFNISIQSDANDVLLGDTVQMKCSVSILNASPNTGDVAFEVRWFQSSMRPPDNGVVPLISMDRYGVVKKSGSNHSS---LERTDQYSFTLSLHSIQHTDVGEYYCSATPWLLSPATGAWSKESELSSGRVLLSVRTQMWESLKMPVGYGLIAALVAGLLSILLGLAVARCCFSRNPLHTPRPHNKLRDLEMD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1QAI9-1", "uniprot_id": "F1QAI9_DANRE", "id": "F1QAI9-1", "name": "", "aln": "MGMTRV--LILLYAAVGLCSCRSVSVSGGPLLRVEGQPLSIRCDVSDYEGPREQDFEWTVTR-ETKTINVISTFDPAFSDRSLQDRIKTGDISIARLADNVVELRIQEAQISDSATYRCSTPSTDSVISGNYEASVQLQVVPNTLIVAPD---PPTPVVPEGGSIRLQCSVSRSFIPGIFLSITWSVK--NRSSLLEDLLTFGPDMSVTVDTVSSQRYTDGGMRLEMGNGVSHSLVLSGVTPADQGLYMCTASLWTREQGIWSRIQEKSMEMGDVTVTPAVNSLAVHVQNDSTLSTGDSLVLLCSVMVSGASAVDLDVTWLQNDT--------HVLGHLSRDGVQTDSSSRAVDVKRLGKWDYQLKIQDVETSDGGLYTCKVNVWIQRDTGRWYKAAEKISDPVRVHVIKHNPEYTAVLSSSVTAKFSGDPTELECKVMNVSNLRSG-RLGVSWLYRDLQPNGTPGSTQTVASLDENGTLVPGRAFKSRVEAGLITATRAEPSMFKLRLLHTTDADAGEYMCVVSAWIPSPHGHWKKVAEHLTPAVKVSFANKRPVLGVVARRLREATAVGSTFEMSCQASVQNLPSGSAFSISVLSEES-VGASG----RRRASLDPDLLLKLEDVGEPARSHSLMLLKTKKTEFEFRIPAVRLSDRGFYYCEMKAWTRQIGDEWVEVAKGLSNKVQIAFTHKGPTFDVSISSDVSSVFPWETVKMECDVSVSGTSPSADDVAYELKWFLSRLRGSSS-PTLLASMDRWGVVRKSPRNDSSDCSLERLEARRFALSVHNTQDSDAGDYHCSVTPWVRSSVNGVWSRAAEISSQRVFLNVRFALWSSMKLPLLYGICASATVGVVSLILGLVCAHCCCKTSTPATPRSR-KLMELEMD", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. :* .:.:. * * *. ..*::* * : * *:**:*:** :*:*:* . . : : **:: .*. ::*:: :* : : : .***:::..: :*.. *:*******:.:.***: ::::*: ::* *.* * : * ...*:* .: : .*:: *.: . ..:*:: : . . *** .*.::*: .. : * : . .**:* * * .. * : * .* *:: ::. * : : :* . * * . :.:**** *:* : . *: *** * : :* :* : :* * :.* : * : :: . * :*: :*:: * * * * *:** . :. * : : : .* : :: : .** * *:: : :.*.****:*:.* :*: . . :*: : *:. . .. : **. * :::**: :..* ..::* * *:.:*: .::** *:* * :.**: .. * : .. ** ::: * .** *: *: **. .* : ::: * ::: .: ...*:*::: ** .. * *:** *:* .. : .* *** . * *.:*. :. * *:*:**.***: *.. * *.: :*: * :::.*: : .::* *: *: : . *::* ::* :: * . . * * : :* .:***", "identical_positions": 184, "similar_positions": 267, "identity": "20.72%" }, { "cls_id": "homologset.agr.MGI:1277116", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88502-1", "uniprot_id": "PDE8A_MOUSE", "id": "O88502-1", "name": "High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A", "aln": "MGCAPS-------------------------------IHTSENRTFSHSDG-------------------------EDEDVDVDVPGPAPRSIQRWSTAP-----GLVEPQPRDNGASKVSVADVQFG---------------------PMRFHQD---------------QLQVLLVFTKEDSQCNGFHRACEKAGFKCTVTKEVQTVLTCFQD-----KLHDIIIIDHRYPRQMDAETLCRSIRSSKFSENTVIVGVVRRVDKE-ESSLMPFLAAGFTRRFIENPNVMACYNELLQLACGEVRSQLKLRACNSVFTALEKSQEAIEITSEDHIIQYANPAFESTMGYQSGELIGKELAQVPINEK-KGDLLDAINSCVTVDKEWQGVYHTQKKNGDNIQQNVKIIPVIGQGGKIRHYVSIIRVCNGNNKVETTTECVQTDSQTDN-QAGKHKDRRKHSMDAKAVSSRTSDVSS-QRRHSSLARIHSMMIEAPITKVINIINAAQENSPVPVTEALNRVLDILRTTELYSPQFN-AQDD-PHATDLVGGLMSDG---LRRFSGNEYILATKNLPPLSNNLATPVSLHDVPPRIALAIENEEQWDFDIFELEVATQNRPLIYLGLKTFARFGMCEFLQCSETTLRSWFQMIESNYHSSNPYHNSTHAADVLHATAYFLSRDKIKET--LDRIDEVAALIAATVHDVDHPGRTNSFLCNAGNQLAVLYNDTAVLESHHVALAFQLTLENDQCNIFKQMERNDYRTLRQSIIDMVLATEMTKHFEHVNKFINSINKPLTAQESE-EPDRSLEDIKAMLKTPESRALIKRMMIKCADVSNPCRPLEHCIEWAARISEEYFSQTDEEKQLDLPVVMP-VFDRNTCSIPKSQISFIDYFITDMFDAW-DAFVDLPNLMQHLDDNFRYWKGLDEK------KLRSLRPPPE------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60658-1", "uniprot_id": "PDE8A_HUMAN", "id": "O60658-1", "name": "High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A", "aln": "MGCAPS-------------------------------IHIS-ERLVAEDAP-------------------------SPAAPPLSSGGPRLPQGQKTAALPRTRGAGLLESELRDGSGKKVAVADVQFG---------------------PMRFHQD---------------QLQVLLVFTKEDNQCNGFCRACEKAGFKCTVTKEAQAVLACFLD-----KHHDIIIIDHRNPRQLDAEALCRSIRSSKLSENTVIVGVVRRVDRE-ELSVMPFISAGFTRRYVENPNIMACYNELLQLEFGEVRSQLKLRACNSVFTALENSEDAIEITSEDRFIQYANPAFETTMGYQSGELIGKELGEVPINEK-KADLLDTINSCIRIGKEWQGIYYAKKKNGDNIQQNVKIIPVIGQGGKIRHYVSIIRVCNGNNKAEKISECVQSDTHTDN-QTGKHKDRRKGSLDVKAVASRATEVSS-QRRHSSMARIHSMTIEAPITKVINIINAAQESSPMPVTEALDRVLEILRTTELYSPQFG-AKDDDPHANDLVGGLMSDG---LRRLSGNEYVLSTKNTQMVSSNIITPISLDDVPPRIARAMENEEYWDFDIFELEAATHNRPLIYLGLKMFARFGICEFLHCSESTLRSWLQIIEANYHSSNPYHNSTHSADVLHATAYFLSKERIKET--LDPIDEVAALIAATIHDVDHPGRTNSFLCNAGSELAILYNDTAVLESHHAALAFQLTTGDDKCNIFKNMERNDYRTLRQGIIDMVLATEMTKHFEHVNKFVNSINKPLATLEENGETDKNQEVINTMLRTPENRTLIKRMLIKCADVSNPCRPLQYCIEWAARISEEYFSQTDEEKQQGLPVVMP-VFDRNTCSIPKSQISFIDYFITDMFDAW-DAFVDLPDLMQHLDNNFKYWKGLDEM------KLRNLRPPPE------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58HUM1-1", "uniprot_id": "A0AC58HUM1_DANRE", "id": "A0AC58HUM1-1", "name": "Phosphodiesterase", "aln": "MGCASS-------------------------------IHIS-DRVVYHSGK-------------------------ESEEP------PHTHSHTHTCTP---------DTGDRSSAGGQGSLTELQFG---------------------PMKLNED---------------QLQVLLVFARDDAQSSSFISACERCGFGCSVCRTPEAALECVLQ-----KSPDLIIIDHRHPRGLDGEALCRSIRAVSCSHNTVIVAVVKRPDRE-EATVMPLISAGFNRRFVENSSMMSCYNELLQLHHGEIRAQIKLRACNALFTALEQSQEAIEISSEDHIIQYVNPAYECMMGYQCGELL-KENTEVPKSERNRPDLLDNISSCMLRGKEWQGVYYAKKKNGDSVQQNVRMTPVIGQGGKVRHCVSVNRPLNDHNKTEKSCERVQAESQTDIPQSSKHKDRRKGSLDVRSTTSRGSDAGSSQRRHSSMARIHSMTIEAPITKVINIINAAQESSPLPVAEALDRVLEILRSSELYSPQLA-TKEEDPHTNDLVGGLMTDG---LRRLSGNEYIFTTKQLHHMTSHQTTPLSLNDIPQCIAQTMENEDSWDFDIFNLESATLKRPLAFLGLKLFSRFGVCEFLGCAEATLRSWLQNIEASYHGSNPYHNSTHAADVLHATAYFLCKERVKQS--LDPIDEVAALIAAAVHDVDHPGRTNSFLCNAGSELAVLYNDTAVLESHHAALAFQITTRDDKSNIFRNMERNEYRTLRQAIIDMVLATEMTKHFEHVNKFVNSINKPLAALEENGGSDDE-DSVKSVLTSPENRILVKRMLIKCADISNPCRPLELCIEWAGRISEEYFAQTDEEKQRGLPVVMP-VFDRHTCSIPKSQISFIDYFITDMFDAW-DAFADLPNLMQHLDNNFKYWKSLDEQ------KLRSLRAPPEEHA---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6NNF2-1", "uniprot_id": "PDE8_DROME", "id": "Q6NNF2-1", "name": "High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8", "aln": "MGCSPSTLPPAPSAGQTGERGSLPLDASEKDESRLFCIKLRRSRLRRCSCGGVTLQPPSDGNGSTAGDNLCGQVLLNPLQTKSEADYEKLSTGKKDSIVTVAALGNFTHSVVRRATGSTGTSGTSSSGGNSRPGHRKSSLALALTPEDEPMDVYQRNLMDLKYPTVLPPNPPLKALLVFHKSDSICEAITAACQRHQLDVTLVKSKEEALDTLQKSYATAQCYHLIIIDARSSKNLDAEHIARTIRHTHGHHLTTIIAVCKKSFFEKDDVLIALLDAGVNRCVAETTNLAMCSVELKQILHSIIRPHNVMSTQQALYTALHRLKEVVLITDDLLRIQYANRATERLLNMRLDEIISKQLEDIFVSDL------STISEQCKNIKEFDGILTVRRKSQEGIPMHVRVVPVACIGSAPTHLIFNFDVPGGQ------MDFIATLPQPKEAPRGSLHSVRRCSFDVRSIASDG-------LRRTSLAKLTSLPLEAPITKIINLLSQVQENCSADEARLIDKVLEFLKREGLYSPQMKEIRTDDPIATDLIGALLTGPSVYSSRRSSNDSIIRTG--SSTRTAAIVPAKMKSNP-IIMELLDESLSWDFDIFKLEEITDYHPLLYLGMEMFRRFDVFATLNIDENVCKAWLAVIEAHYRKSNTYHNSTHAADVMQATGAFITQLTNKDMLVMDRMEEATALIAAAAHDVDHPGRSSAFLCNSNDALAVLYNDLTVLENHHAAITFKLTLGDDKINIFKNLDKETYKSARSTIIDMILATEMTRHFEHLAKFVSVFGG-----EEPRDHNPQ--------TDEETSILMRRMLIKVADVSNPARPMQFCIEWARRIAEEYFMQTDEEKQRHLPIVMP-MFDRATCSIPKSQIGFIEYIIQDMMHAW-ESFIDMPQLITYMQINYSQWKKYDEQGVNTLAEIMAKQPPVGKMANSK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P06776-1", "uniprot_id": "PDE2_YEAST", "id": "P06776-1", "name": "3',5'-cyclic-nucleotide phosphodiesterase 2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSTLFLIGIHEIE-----------------------------------KSQTIVQNEHYFDRVIELQDLDS------------------------------LMVALYKDRVSPFPNVHNFETGVSIVLYDPSKFQLSVRQLDVLFKRFFPS--------------FNISAIDHTREENLQRLECVERENSICRNR--------------ITRINHWMYHHHDDTPDGINKNS--------------YGTVNGN-----------------------------------------------------------SVPTQACEANIYTLLLHLNDSK--AQHLRKASVPRLIRNIEFMSFLSDPIEKISQEGSHYWNILS-----------------------------------------------------TWDFCALSLS----TQELIWCGFTLIKKLSKDAKVLIADNKLLLLLFTLESSYHQVNKFHNFRHAIDVMQATWRLCTYLLKDNP-----VQTLLLCMAAIGHDVGHPGTNNQLLCNCESEVAQNFKNVSILENFHRELFQQLLSEHWPQLLSISKKKFDFISEAILATDMALHSQYEDRLMHENPMKQITLISLIIKAADISNVTRTLSISARWAYLITLEFNDCALLETFHKAH--RPEQDCFGDSYKNVDSPKEDLESIQNILVNVTDPDDIIKDHPHIPNGQIFFINTFAEVFFNALSQKFSGLKFLSDNVKINKEYWMKHKKPQ---------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :..*::: : : :: : : :: : : :: * . ..: : : . : : : : ::. : : * : . .: : : : : . : : .. :.: : : : ** * .:: :. : . : ::: :. : * : : . :::. *** :.*. : * : *: : ::. : : : :*: *: * :** *: **::** : .: :: :** ***.*** .. :***. . :* ::: ::**..* : :: . : . .: : : ** * :: :: * : . . : ::: . :: ** : *: : : :. : :. :: : :. * : : **:.** **: : ::.* : * .: * :. * * .: ", "identical_positions": 57, "similar_positions": 168, "identity": "5.99%" }, { "cls_id": "homologset.agr.MGI:1277117", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6P9X4-1", "uniprot_id": "TP4A2_RAT", "id": "Q6P9X4-1", "name": "Protein tyrosine phosphatase type IVA 2", "aln": "----MN----RPAPVEISYENMRFLITHNPTNATLNKFTEELKKYGVTTLVRVCDATYDKAPVEKEGIHVLDWPFDDGAPPPNQIVDDWLNLLKTKFREEPGCCVAVHCVAGLGRAPVLVALALIECGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFRD-TNGHCCVQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70274-1", "uniprot_id": "TP4A2_MOUSE", "id": "O70274-1", "name": "Protein tyrosine phosphatase type IVA 2", "aln": "----MN----RPAPVEISYENMRFLITHNPTNATLNKFTEELKKYGVTTLVRVCDATYDKAPVEKEGIHVLDWPFDDGAPPPNQIVDDWLNLLKTKFREEPGCCVAVHCVAGLGRAPVLVALALIECGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFRD-TNGHCCVQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q12974-1", "uniprot_id": "TP4A2_HUMAN", "id": "Q12974-1", "name": "Protein tyrosine phosphatase type IVA 2", "aln": "----MN----RPAPVEISYENMRFLITHNPTNATLNKFTEELKKYGVTTLVRVCDATYDKAPVEKEGIHVLDWPFDDGAPPPNQIVDDWLNLLKTKFREEPGCCVAVHCVAGLGRAPVLVALALIECGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFRD-TNGHCCVQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O61722-1", "uniprot_id": "PRL1_DROME", "id": "O61722-1", "name": "PRL-1 phosphatase", "aln": "MSITMRQKDLRPAPALIEYKGMKFLITDRPSDITINHYIMELKKNNVNTVVRVCEPSYNTDELETQGITVKDLAFEDGTFPPQQVVDEWFEVLKDKYQQNPEACVAVHCVAGLGRAPVLVALALIELGLKYEAAVEMIRDKRRGAINAKQLSFLEKYKPKARLKHKNGHKNSCSVQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. ****. *.*:.*:****..*:: *:*:: **** .*.*:****:.:*:. :*.:** * * .*:**: **:*:**:*:::** *::::* .*********************** *:*** **::**:*****:*:*** :****:** **:.:: :. *.**", "identical_positions": 95, "similar_positions": 53, "identity": "53.98%" }, { "cls_id": "homologset.agr.MGI:1277119", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LWY9-1", "uniprot_id": "A0ABK0LWY9_RAT", "id": "A0ABK0LWY9-1", "name": "", "aln": "MTAELKETMGRASWSPVKVKKEEDEE-CVISQASSQQVFSGNIKNWALGEGPYVSICGSEEEEKGQKMFWDMAVVLKATQEAAAASPLGSYSLTGTLVKSEILEPHGNPTPLGTKTKNLELLIPKTEICDDSDKPPMILGRIQKGDLQSSELGESCEKGNMFKKLRIRREKGDL--RKVKDCPLSGSFQDEEEEKSKKTRGKYSLSSAPAKKQKIQPGQKPFTCSECGKGFSQSANLVVHQRIHTGEKPFECHECGKAFIQSANLVVHQRIHTGQKPYVCGKCGKAFTQSSNLTVHQKIHSLEKTFKCGECEKAFSYSSQLARHQKVHITEKCYECNECGKTFTRSSNLIVHQRIHTGEKPFACNDCGKAFTQSANLIVHQRSHTGEKPYECKECGKAFSCFSHLIVHQRIHTAEKPYDCSECGKAFSQLSCLIVHQRIHSGDLPYVCNECGKAFTCSSYLLIHQRIHNGEKPYSCNECGKAFRQRSSLTVHQRTHTGEKPYECAKCGAAFISNSHLMRHHRTHLVQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "G3X9I0-1", "uniprot_id": "G3X9I0_MOUSE", "id": "G3X9I0-1", "name": "", "aln": "MTTELKETMGRASWDPEKVKMEEDDE-SVISQASSQQVYYENDKDCAPGEGPYGSISVSEDEEKGQEMFREMAVVLKATQEAAAASPFGSYSLAGTLAESQILELHGNPTPTGAKSKNLELLIPKKEISDDSEKPPMILGRIQKGDLQGPELGESCEKGNVLKGLRIKEEKGDLGEATVKDCPLSESFRDEEE--SKKSRGKYSLRSTPGKNQKIQPGQKPFTCSECGKGFSQSANLVVHQRIHTGEKPFECHECGKAFIQSANLVVHQRIHTGQKPYVCGKCGKAFTQSSNLTVHQKIHSLEKTFKCSECEKAFSYSSQLARHQKVHITEKCYECNECGKTFTRSSNLIVHQRIHTGEKPFACSDCGKAFTQSANLIVHQRSHTGEKPYKCKDCEKAFSCFSHLIVHQRIHTAEKPYDCSECGKAFSQLSCLIVHQRIHSGDLPYVCNECGKAFTCSSYLLIHQRIHNGEKPYSCNECGKAFRQRSSLTVHQRTHTGEKPYECAKCGAAFISNSHLMRHHRTHLVE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P13682-1", "uniprot_id": "ZNF35_HUMAN", "id": "P13682-1", "name": "Zinc finger protein 35", "aln": "MTAELREAMALAPWGPVKVKKEEEEEENFPGQASSQQVHSENIKVWAPVQGLQTGLDGSEEEEKGQNISWDMAVVLKATQEAPAASTLGSYSLPGTLAKSEILETHGTMNFLGAETKNLQLLVPKTEICEEAEKPLIISERIQKADPQGPELGEACEKGNMLKRQRIKREKKDFRQVIVNDCHLPESFKEEENQKCKKSGGKYSLNSGAVKNPKTQLGQKPFTCSVCGKGFSQSANLVVHQRIHTGEKPFECHECGKAFIQSANLVVHQRIHTGQKPYVCSKCGKAFTQSSNLTVHQKIHSLEKTFKCNECEKAFSYSSQLARHQKVHITEKCYECNECGKTFTRSSNLIVHQRIHTGEKPFACNDCGKAFTQSANLIVHQRSHTGEKPYECKECGKAFSCFSHLIVHQRIHTAEKPYDCSECGKAFSQLSCLIVHQRIHSGDLPYVCNECGKAFTCSSYLLIHQRIHNGEKPYTCNECGKAFRQRSSLTVHQRTHTGEKPYECEKCGAAFISNSHLMRHHRTHLVE", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:**:*:*. *.*.* *** **::* . .*******. * * * :* .: **:*****:: :***********.***.:*****.***.:*:*** **. . *:::***:**:**.**.::::** :* ****.* *..****:*****::* **:.** *: *:** *. **::**: .**: ***** * . *: * * ******** ******************************************************.***************************.*******************************************************.*************************:**:* ******************************************************************************:***************************** *********************:", "identical_positions": 414, "similar_positions": 64, "identity": "78.56%" }, { "cls_id": "homologset.agr.MGI:1277120", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JHU5-1", "uniprot_id": "ARFP1_RAT", "id": "Q9JHU5-1", "name": "Arfaptin-1", "aln": "MAEESPKNSAAEIPVTSNGEVGDAHEHGYNRDLKHSLPSGLGLSETQITSHGFDSTKEGVTEAGASQGSSAPPLPCVLSPSRVAASQLTQ--HAG-------GQRTHTKGGPVILADEIKNPAMEKLELVRKWSLNTYKCTRQIISEKLGRGSRTVDLELEAQIDILRDNKKKYENILKLAQTLSTQLFQMVHTQKQLGDAFADLSLKSLELHEEFGYNADTQKLLAKNGETLLGAINFFIASVNTLVNKTIEDTLMTVKQYENARIEYDAYRTDLEELNLGPRDANTLPKIEQSQHLFQIHKEKYDKMRSDVSVKLKFLEENKVKVLRNQLALFHSAVAAYFAGNQKQLEQTLKQFHVKLKTPGVDAPSWLEEQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "G5E8V9-1", "uniprot_id": "ARFP1_MOUSE", "id": "G5E8V9-1", "name": "Arfaptin-1", "aln": "MAQESPKNSAAEIPVTSNGEVDDAHEHGYNRDLKHSLPSGLGLSETQITSHGFDSTKEGVTEAGAPQGSSAPPLPCVLSPSRVAASKLTQ--QAGDLTVPAGGQRTHTKGGPVILADEIKNPAMEKLELVRKWSLNTYKCTRQIISEKLGRGSRTVDLELEAQIDILRDNKKKYENILKLAQTLSTQLFQMVHTQKQLGDAFADLSLKSLELHEEFGYNADTQKLLAKNGETLLGAINFFIASVNTLVNKTIEDTLMTVKQYENARVEYDAYRTDLEELNLGPRDANTLPKIEQSQHLFQIHKEKYDKMRSDVSVKLKFLEENKVKVLRNQLVLFHSAVAAYFAGNQKQLELTLKQFHVRLKTPGVDAPSWLEEQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P53367-1", "uniprot_id": "ARFP1_HUMAN", "id": "P53367-1", "name": "Arfaptin-1", "aln": "MAQESPKNSAAEIPVTSNGEVDDSREHSFNRDLKHSLPSGLGLSETQITSHGFDNTKEGVIEAGAFQGSPAPPLPSVMSPSRVAASRLAQ--QGSDLIVPAGGQRTQTKSGPVILADEIKNPAMEKLELVRKWSLNTYKCTRQIISEKLGRGSRTVDLELEAQIDILRDNKKKYENILKLAQTLSTQLFQMVHTQRQLGDAFADLSLKSLELHEEFGYNADTQKLLAKNGETLLGAINFFIASVNTLVNKTIEDTLMTVKQYESARIEYDAYRTDLEELNLGPRDANTLPKIEQSQHLFQAHKEKYDKMRNDVSVKLKFLEENKVKVLHNQLVLFHNAIAAYFAGNQKQLEQTLKQFHIKLKTPGVDAPSWLEEQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BI85-1", "uniprot_id": "A0A8M2BI85_DANRE", "id": "A0A8M2BI85-1", "name": "", "aln": "MAEDARRSPAAQISVTRNGEADKSHEDVFQRDMSH-VSSGPVTSHFHNSPENYAMT-EGVVQVGPDAGSPPQTNTPRVVASPAAASRLARSISDSQVEIQKGALREQQMGGAVVLADDIKSPAIEKLELVRKWSINTYKCTKQILSEKLGRGSRTVDLELEAQIDVLRDNKRKYEHVIKLAQTLCTQLEQMLMTQRQLGDAFADLSLKTPALHEEFGYNAETQKLLAKNGETLLGAISFFIANVKTLVDKTIEDTLINIKQYEAARIEYDAYRTDLEELNLGPRDANTLPKIELSQQQFQIHREKYEKMRNDVSVKLKFLEENKVKVLHNQLILFHNAIAAYFAGNQQQLEQTLKQFHIKLKLPGGETPSWLEEH", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VGQ8-1", "uniprot_id": "Q9VGQ8_DROME", "id": "Q9VGQ8-1", "name": "", "aln": "MTD---RERSIHEMLKDAPSLNDSCGAVHTGTEGGSGILG-SASSHSIAGGGGGGGNVGVGVGGPFGAPSSLPLRNHSAPTTPMSPSSPP--SGN-------GILSPTDSG----SGSIIRTSASKIDSLKNWSISTYKCTRQIMLEKLGKSQRTVDSELEAQIEQLRETQRKYLSILRLTRAFSSHFQHVVVTQHALADSFADLAQKNPELQKEFTCNSETQRNLTKNGELLLNALNFFISSVNTLCNKTIDDTLLTIRQYETARIEFDAYRMDLENT--KPELTPSAVALEETQRSYAQHKEQYEKLRSDVAVKMQFLDENRIKVMHKQLILLHNAIAAYFSGNAMALESTLKQFNIKLKSPNAVTGSWLEQ-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:: :. : . :. . ..: . * * : . ** *. .... . .: :. . . . .* :..* .: .*:: :::**:.*****:**: ****:..**** ******: **:.::** :::*::::.::: ::: **: *.*:****: *. *::** *::**: *:**** **.*:.***:.*:** :***:***:.::*** **:*:**** ***: *. : : :* :*: : *:*:*:*:*.**:**::**:**::**:::** *:*.*:****:** ** *****:::** *. : ****: ", "identical_positions": 128, "similar_positions": 123, "identity": "34.13%" }, { "cls_id": "homologset.agr.MGI:1277122", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "I6L9G5-1", "uniprot_id": "RCN3_RAT", "id": "I6L9G5-1", "name": "Reticulocalbin-3", "aln": "MMWRWTLMLLLLLLRHWALGKPSPDAGPHGQDR-VHHGTPLSEAPHDDAHGNFQYDHEAFLGRDVAKEFDQLTPEESQARLGRIVDRMDLAGDSDGWVSLAELRAWIAHTQQRHIRDSVSAAWHTYDTDRDGRVGWEELRNATYGHYE--PGEEFHDVEDAETYKKMLARDERRFRVADQDGDSMATREELTAFLHPEEFPHMRDIVVAETLEDLDKNKDGYVQVEEYIADLYSAEPGE-EEPAWVQTERQQFRDFRDLNKDGRLDGSEVGYWVLPPSQDQPLVEANHLLHESDTDKDGRLSKAEILSNWNMFVGSQATNYGEDLTRHHDEL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BH97-1", "uniprot_id": "RCN3_MOUSE", "id": "Q8BH97-1", "name": "Reticulocalbin-3", "aln": "MMWRWSFLLLLLLLRHWALGKPSPDAGPHGQDR-VHHGTPLSEAPHDDAHGNFQYDHEAFLGRDVAKEFDKLSPEESQARLGRIVDRMDLAGDSDGWVSLAELRAWIAHTQQRHIRDSVSAAWHTYDTDRDGRVGWEELRNATYGHYE--PGEEFHDVEDAETYKKMLARDERRFRVADQDGDSMATREELTAFLHPEEFPHMRDIVVAETLEDLDKNKDGYVQVEEYIADLYSEEPGE-EEPAWVQTERQQFREFRDLNKDGRLDGSEVGYWVLPPSQDQPLVEANHLLHESDTDKDGRLSKAEILSNWNMFVGSQATNYGEDLTRHHDEL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96D15-1", "uniprot_id": "RCN3_HUMAN", "id": "Q96D15-1", "name": "Reticulocalbin-3", "aln": "MMWRPSVLLLLLLLRHGAQGKPSPDAGPHGQGR-VHQAAPLSDAPHDDAHGNFQYDHEAFLGREVAKEFDQLTPEESQARLGRIVDRMDRAGDGDGWVSLAELRAWIAHTQQRHIRDSVSAAWDTYDTDRDGRVGWEELRNATYGHYA--PGEEFHDVEDAETYKKMLARDERRFRVADQDGDSMATREELTAFLHPEEFPHMRDIVIAETLEDLDRNKDGYVQVEEYIADLYSAEPGE-EEPAWVQTERQQFRDFRDLNKDGHLDGSEVGHWVLPPAQDQPLVEANHLLHESDTDKDGRLSKAEILGNWNMFVGSQATNYGEDLTRHHDEL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W0H8-1", "uniprot_id": "Q9W0H8_DROME", "id": "Q9W0H8-1", "name": "Reticulocalbin-3", "aln": "MARTRIQMLLLVVALTAVISGASASSIPEELPHNPLEHDPLHPRHFDGGEHNAQFDHEAFLGPDESKKFDSLTPEESRRRLGVIVDRID--ENKDGSVTLAELKNWIAYTQRRYIEEDVGRVWKQHNPDNNETISWDSYMQTVYGFMDDLSPDEKEQEENGVSYKSLLKRDRYRWSVADQDLDDNLTKDEFTAFLHPEDHPSMKGVVLRETITDLDKDHDGKISVDEYIGDMYRSTGAEDEEPEWVANEREAFSTHRDLDKDGYLNEEEVKQWIAPHDFDHSEAEAKHLLFEADADHDDKLTKEEILDKYDVFVGSQATDFGEALAR-HDEF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :***:: . . .*..: *. : . ** .*... * *:******* : :*:**.*:****: *** ****:* : ** *:****: ***:**:*:*.:.*. .*. ::.*.: :.*:. ::.**. . :* .: *:. :**.:* **. *: ***** *. *::*:*******:.* *:.:*: **: ***:::** :.*:***.*:* .* *** ** .**: * .***:*** *: .** *: * *:. .**:***.*:*:*:*.:*:* ***.::::*******::** *:* ***:", "identical_positions": 142, "similar_positions": 107, "identity": "42.77%" }, { "cls_id": "homologset.agr.MGI:1277124", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6P7S1-1", "uniprot_id": "ASAH1_RAT", "id": "Q6P7S1-1", "name": "Acid ceramidase", "aln": "MLGRSLLTWVL-AAAVTCAQAQQVPPWTEDCRKSTYPPSGPTYRGPVPWYTINLDLPPYKRWHELLAHKAPVLRTLVNSISNLVNAFVPSGKIMQMVDEKLPGLIGSIPGPFGEEMRGIADVTGIPLGEIISFNIFYELFTMCTSIITEDGKGHLLHGRNMDFGIFLGWNINNNTWVVTEELKPLTVNLDFQRNNKTVFKATSFAGYVGMLTGFKPGLLSLTLNERFSLNGGYLGILEWMFGKKNAQWVGFITRSVLENSTSYEEAKNILTKTKITAPAYFILGGNQSGEGCVITRERKESLDVYELDPKHGRWYVVQTNYDRWKNTLFLDDRRTPAKKCLNHTTQKNLSFATIYDVLSTKPVLNKLTVFTTLIDVTKDQFESHLRDCPDPCIGW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WV54-1", "uniprot_id": "ASAH1_MOUSE", "id": "Q9WV54-1", "name": "Acid ceramidase", "aln": "MRGQSLLTWVL-AAAVTCAQAQDVPPWTEDCRKSTYPPSGPTYRGPVPWHTINLDLPPYKRWHELLAQKAPALRILVNSITSLVNTFVPSGKLMKMVDQKLPGMIGSLPDPFGEEMRGIADVTGIPLGEIISFNIFYELFTMCTSIITEDEKGHLLHGRNMDFGIFLGWNINNNTWVVTEELKPLTVNLDFQRNNKTVFKATSFVGYVGMLTGFKPGLFSLSLNERFSINGGYLGILEWMFGRKDAQWVGFITRSVLENTTSYEEAKNTLTKTKIMAPVYFILGGKKSGEGCVITRERKESLDVYELDPKHGRWYVVQTNYDRWKNTLFIDDRRTPAKKCLNHTTQKNLSFATIYDVLSTKPVLNKLTVFTTLMDVTKGQFESHLRDCPDPCIGW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13510-1", "uniprot_id": "ASAH1_HUMAN", "id": "Q13510-1", "name": "Acid ceramidase", "aln": "MPGRSCVALVLLAAAVSCAVAQHAPPWTEDCRKSTYPPSGPTYRGAVPWYTINLDLPPYKRWHELMLDKAPVLKVIVNSLKNMINTFVPSGKIMQVVDEKLPGLLGNFPGPFEEEMKGIAAVTDIPLGEIISFNIFYELFTICTSIVAEDKKGHLIHGRNMDFGVFLGWNINNDTWVITEQLKPLTVNLDFQRNNKTVFKASSFAGYVGMLTGFKPGLFSLTLNERFSINGGYLGILEWILGKKDVMWIGFLTRTVLENSTSYEEAKNLLTKTKILAPAYFILGGNQSGEGCVITRDRKESLDVYELDAKQGRWYVVQTNYDRWKHPFFLDDRRTPAKMCLNRTSQENISFETMYDVLSTKPVLNKLTVYTTLIDVTKGQFETYLRDCPDPCIGW", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* *:* :: ** ****:** **..*********************.***:***************: .***.*: :***:..::*:******:*::**:****::*.:*.** ***:*** **.*****************:****::** ****:********:********:***:**:********************:**.*************:**:******:**********::*:*:. *:**:**:****:******** ****** **.******::*********:***********.*:**************:.:*:******** ***:*:*:*:** *:***************:***:****.***::***********", "identical_positions": 308, "similar_positions": 72, "identity": "77.97%" }, { "cls_id": "homologset.agr.MGI:1277133", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5I0E2-1", "uniprot_id": "PHF11_RAT", "id": "Q5I0E2-1", "name": "PHD finger protein 11", "aln": "MAEETAPPCGPVSTGGSL-----------------SPEKMEKRTCALCPDGHEWSVIY-FAPSANIAAHENCLLYSSGLVECGPHDPRNPARSFAVKSVKKEIWRGRRLKCSLCNKGGATVGCDLSSCRKSYHYVCAKKDHAIPQVDEDLGTYKIFCPEHPPQQEETTERAD-------------SPSVKKT-GKKKSLSSGPPTEPKK--------------MKFSRFKRLMKEEPHGHKDAAVKAPFLKK------------------------------------------------CLEAGLLT------------ELFEQILEKMDSIHGRFMDETASESDYEGIKT---LLFDCGLFGDILRKFQEVIKSKTCEYEERLNQMKQK--------------------------------------------LEALADLQENLCSFQECGDLDPSGSTSGSLLPPEDHQCRCQESPEVQAGSGDSL--------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A6H5X4-1", "uniprot_id": "PHF11_MOUSE", "id": "A6H5X4-1", "name": "PHD finger protein 11", "aln": "MAQETAPPCGPVSRGDSP-----------------IIEKMEKRTCALCPEGHEWSQIY-FSPSGNIVAHENCLLYSSGLVECETLDLRNTIRNFDVKSVKKEIWRGRRLKCSFCNKGGATVGCDLWFCKKSYHYVCAKKDQAILQVDGNHGTYKLFCPEHSPEQEEATESAD-------------DPSMKKKRGKNKRLSSGPPAQPKT--------------MKCSNAKRHMTEEPHGHTDAAVKSPFLKK------------------------------------------------CQEAGLLT------------ELFEHILENMDSVHGRLVDETASESDYEGIET---LLFDCGLFKDTLRKFQEVIKSKACEWEERQRQMKQQ--------------------------------------------LEALADLQQSLCSFQENGDLDCSSSTSGSLLPPEDHQVRSQESPEVQAGSGDSL--------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UIL8-1", "uniprot_id": "PHF11_HUMAN", "id": "Q9UIL8-1", "name": "PHD finger protein 11", "aln": "MAQASPPRPERVLGASSPEARPAQEALLLPTGVFQVAEKMEKRTCALCPKDVEYNVLY-FAQSENIAAHENCLLYSSGLVECEDQDPLNPDRSFDVESVKKEIQRGRKLKCKFCHKRGATVGCDLKNCNKNYHFFCAKKDDAVPQSDGVRGIYKLLCQQH-AQFPIIAQSAK-------------FSGVKRKRGRKKPLSGNHVQPPET--------------MKCNTFIRQVKEEHGRHTDATVKVPFLKK------------------------------------------------CKEAGLLN------------YLLEEILDKVHSIPEKLMDETTSESDYEEIGS---ALFDCRLFEDTFVNFQAAIEKKIHASQQRWQQLKEE--------------------------------------------IELLQDLKQTLCSFQENRDLMSSSTSISSLSY------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7URD4-1", "uniprot_id": "A0A8N7URD4_DANRE", "id": "A0A8N7URD4-1", "name": "", "aln": "MGSGQSP-------------------------------STYRIICALCKTSDETETTGPLSSKEDISAHQNCLLFSS-NIYCKNSPTYDDLFGFDLEDVKKEQRRGQKLRCYFCNKTGATVGCEIKRCPRSFHYPCAIKADARAIEDFSTGTYRVYCKSHDPNPIEINDEIDNDVDLVLASVEKHVPAEQHNQSTPDPERTRPSEEVKTPAKASSNGGLTSDQRSCGTADKRRIECDSQEHSPEHKTPTKKKKKRRLEYPDNENPTSADAVMAPEVSAPEESMTVNQPNHSTPLPENTRSCEKLNLSTTGAAADDEDDETDIESVSLSVLNKTHLRHIEESQSVLTYETDPVPCIVILDSGPSLESEISLESCSSRNPSPAHEFVTVPKQEKITPTDRTSPAQTVTPQVPAPNQKRVSDGPSVSPQHPSPTAGLRISAVCTLAQSAIKKEQLSDPPAEVSTSDSQSTVPNCQTRAAKFWTRCNQAGWSEGIFSELMSLLHSLGQRVQSGQASYQDYELAFEALKGSGQLPSIIAQIEKDLEKQEQDLQMKKAALCDAKAALAD", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.. .* . : **** . * . :: . :* **:****:** : * : .* ::.**** **::*:* :*:* ******:: * :.:*: ** * .* * * *:: * .* .: : . .. ::. . . :. . . : * . .. * * ** * : .* . : . *. :.. : ::*: * ** ::*. : .:: . : .: *:: :. : * :. . :: * . :: .* ", "identical_positions": 62, "similar_positions": 91, "identity": "11.01%" }, { "cls_id": "homologset.agr.MGI:1277134", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CJE2-1", "uniprot_id": "PER3_RAT", "id": "Q8CJE2-1", "name": "Period circadian protein homolog 3", "aln": "--------------------------------MDP--CGNPAV--PGGDCPQTRGPG-------LQGSS--GQEGPLQGICVDSS----------------------------------------------------HSEHE---------DRNRMSEELIMVVQEMKKYFPAERHT--KPSTLDALNYALRCVHSVQANSEFFQSLSPRGAR-QAEATVYNLEELTSLASEHTSKN-----TDTFVAVFSFLSGRLVHISEQAAWILNSKKGFLKSLHFVDLLAPRDVRVFYAHTAP-TQLPFWNTWTQRAS-QYECAPVKPFFCRICGGG-DREQKRHYSPFRILPYLVHVHSPAQPEPE-------PCCLTLVEKIHSGYEAPRIPVDKR--VFTTTHTPGCVFLEVDERAVPLLGFLPQDLIGTSILTYLHPEDRPLMVAVHQKVLKYVGHP--PFEHSPIRFCTQNGDYVILDSSWSSFVNPWSRKVSFIIGRHKVRTSPLNEDVFATRIKKAT-SHDEDITELQEQIHRLLLQPVHASASSGYGSLGSSGSQEQHISVTSSSESSGHCVEEAQQEQMTLQQVYASVNKIKNVGQQLYIESMARSSVKPVMETCTEPQGSDEQKDFSS-SQTLKNKS-TDTGSGGDLRPEQHSSSYQQMNCIDSVIRYLTSYSFPALKRKCISCTN-TSSSS---EEAKPNPEAD--GSLRDTEQLLDIPEQE--TTTPSADAEGG--VARTLSTAALSMASGVSQCSCSSTTDHVPPLQSE--------------SVAGACEPWALRTKA-HVTAEGFKPVGLTAAVLSAHTQKEEQNYVDRFREKILTSPYGCYLQQEGRNHAKYACVVGAGATPKHSRCAGSERRKHKRKKLPTPVDSSSSSAHLCPHVRGLLP-----DVQHWSASVT-SPCATGLALPSALVVPNQTPYLLSSFPLQDMAPHGVGDSAPWGAAAECP---PLSAGPHPVSTFPSAYMGTFMTVLLHNSPLFPLWPASFSPYPFLGATGPSQMAP-LVPAMAPDLEPTPSDHGPRRVEENWETHSEEEHPFISSRSSSPLQLNLLQEEMPAPSEYADALRRG--ACPDAKQLCVTGNSGSRSPPCATGELATASVQQESP---------------------------------------------------------------------------SAAASGSSASSVHGSGSDYTSEVSENGQRSQDTHRDR--AFSGAAEESIWRMIERTPQCVLMTYQVPERGRDTVLREDLEKLHSMERQRPQFSSAQKEELAKVRSWIHSHPAPEERQLQRAMSPVKTEV------QLVTLQRPVNSVQQKTPVEQL------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70361-1", "uniprot_id": "PER3_MOUSE", "id": "O70361-1", "name": "Period circadian protein homolog 3", "aln": "--------------------------------MDP--CGDPAV--PGGDCPQTRGPG-------LQGAS--GQEGPLQGTCVDSS----------------------------------------------------HSEHE---------DRNRMSEELIMVVQEMKKYFPAERHT--KPSTLDALNYALRCVHSVQANSDFFQSLGPRGAH-QADVTVYSLEDLTALASEHTSKN-----TDTFAAVFSFLSGRLVHISEQAALILNSKRGFLKSVHFVDLLAPQDVRAFYAHTAP-TQLPFWNNWTQRAS-QYECAPAKPFFCRICGGG-DRE-KRHYSPFRILPYLVHVHSSAQPEPE-------PCCLTLVEKIHSGYEAPRIPVDKR--IFTTTHTPGCVFLEVDERAVPLLGYLPQDLIGTSILTYLHPEDRPLMVAIHQKVLKYAGHP--PFEHSPVRFCTQNGEYVILDSSWSSFVNPWSRKVSFIIGRHKVRTSPLNEDVFATRIKKAA-SNDKDIAELQEQIHKLLLQPVHASASSGYGSLGSSGSQEQHVSITSSSESSGHCPEEGQHEQMTLQQVYASVNKIKNVGQQLYIESMARSSVKPVAETCVEPQGGDEQKDFSS-SQTLKNKSTTDTGSGGNLQQEQPSSSYQQMNCIDSVIRYLTSYSLPALKRKCISCTN-TSSSS---EEAKPIPEVD--SSQRDTEQLLDIRKQE--TTGPSTDIEGG--AARTLSTAALSVASGISQCSCSSTSGHAPPLQSE--------------SVAVACKPWALRTKASHLAAGGFKHVGLTAAVLSAHTQKEEQNYVDRFREKILTSPYGCYLQQESRNRAQYSCVQ-AGSTAKHSRCAGSERQKHKRKKLPAPVDTSSPGAHLCPHVTGLLP-----DEQHWGPSASPSPLGAGLAFPSALVVPSQTPYLLPSFPLQDMASQGVGVSAAWGAAAGCP---PLSAGPQAVAAFPSAYVDTLMTIFLHNAPLFPLWPPSFSPYPSLGAAGSSELAP-LVPAMAPNPEPTTSGHSQRRVEENWEAHS-EELPFISSRSSSPLQLNLLQEEMPAPSESADAVRRG--AGPDAKHHCVTGPSGSRSRHCTSGELATATAQQES-----------------------------------------------------------------------------AAASGSSASSIYFSSTDYASEVSENRQRPQDRQRDE--ALPGAAEESIWRMIERTPECVLMTYQVPERGREEVLKQDLEKLQSMEQQQPLFSPAQREELAKVRSWIHSHTAPQEGHLQSCVACEDRGS------VGDTAEVLEQHPAEDTS----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P56645-1", "uniprot_id": "PER3_HUMAN", "id": "P56645-1", "name": "Period circadian protein homolog 3", "aln": "---------------------------------MP--RGEAPG--PGRRGAKDEALG-------EESGERWSPEFHLQRKLADSS----------------------------------------------------HSEQQ---------DRNRVSEELIMVVQEMKKYFPSERRN--KPSTLDALNYALRCVHSVQANSEFFQILSQNGAP-QADVSMYSLEELATIASEHTSKN-----TDTFVAVFSFLSGRLVHISEQAALILNRKKDVLASSHFVDLLAPQDMRVFYAHTAR-AQLPFWNNWTQRAA-RYECAPVKPFFCRIRGGE-DRKQEKCHSPFRIIPYLIHVHHPAQPELESE-----PCCLTVVEKIHSGYEAPRIPVNKR--IFTTTHTPGCVFLEVDEKAVPLLGYLPQDLIGTSILSYLHPEDRSLMVAIHQKVLKYAGHP--PFEHSPIRFCTQNGDYIILDSSWSSFVNPWSRKISFIIGRHKVRTSPLNEDVFATKIKKMN-DNDKDITELQEQIYKLLLQPVHVSVSSGYGSLGSSGSQEQLVSIASSSEASGHRVEETKAEQMTLQQVYASVNKIKNLGQQLYIESMTKSSFKPVTGTRTEPNGGGECKTFTSFHQTLKNNS-VYTEPCEDLRNDEHSPSYQQINCIDSVIRYLKSYNIPALKRKCISCTNTTSSSS---EEDKQNHKADDVQALQAGLQIPAIPKSEMPTNGRSIDTGGG--APQILSTAMLSLGSGISQCGYSSTIVHVPPPETAR-------------DATLFCEPWTLNMQPAPLTSEEFKHVGLTAAVLSAHTQKEEQNYVDKFREKILSSPYSSYLQQESRSKAKYSYFQ-GDSTSKQTRSAGCRKGKHKRKKLPEPPDSSSSNTGSGPR-RGAHQ-----NAQPCCPSAASSPHTSSPTFPPAAMVPSQAPYLVPAFPLPAATSPGREYAAPGTAPEGLHGL-PLSEGLQPYPAFPFPYLDTFMTVFLPDPPVCPLLSPSFLPCPFLGATASSAISPSMSSAMSPTLDPPPSVTSQRREEEKWEAQS-EGHPFITSRSSSPLQLNLLQEEMPRPSESPDQMRRN--TCP-QTEYCVTGNNGSESSPATTGALSTGSPPRENPSHPTASALSTGSPPMKNPSHPTASALSTGSPPMKNPSHPTASTLSMGLPPSRTPSHPTATVLSTGSPPSESPSRTGSAASGSSDSSIYLTSSVYSSKISQNGQQSQDVQKKE--TFPNVAEEPIWRMIRQTPERILMTYQVPERVKEVVLKEDLEKLESMRQQQPQFSHGQKEELAKVYNWIQSQTVTQEIDIQACVTCENEDS------ADGAATSCGQVLVEDSC----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PBM5-1", "uniprot_id": "A0A8M1PBM5_DANRE", "id": "A0A8M1PBM5-1", "name": "", "aln": "MPGGDGFPDGEQDNSSPGPDIHTGQTDQTSSGQDPGTSGNISA--SGEEEEAEERIGRRSSGCEESGGEQTHEDVDMNSTHTSSSGNDSIHHRHHHHHRHHHHHHHHSSSNCSPGSTTGSGSTKSSKSATGSSSSSFHSTHHTECGEQTETGREHTHREMMHTVQEMKKRLPSEKRSRSKASTVEALHYALNCVKQVQANSEYYNLLMSSGLDERRDATVCTLEELEGFTSEHTLKN-----TDSFVVVFSLASGKVVYASEQASSVLHCKRKFLESAKFVEMLYHQDVNVFYSHTAQ-PRLPSWNLGTDSAAVLFECAQVKSFFCRIRGGK-DRDGDMRYSPFRITPYLLKVQGSSG-EEE-------PCCLALAERIISGYEAPRIPMDKR--IFSTTHSPGCVFLEVDDRAVPLLGYLPQDLIGTSVLTCLHPDDRLLMLAMHRKIVKYAGQP--PFEHSPIRFRCQNGDYVTLDSSWSSFINPWSRKVAFIIGRHKVRTGPLNEDVFAARSKADQPVTCEDVKELQAMIHKLFLQPVHNNGSSGYGSLGSNGSHEHYISVASSSDSNGNLWEDSHRETMTLQQFCADVNKVKNWGQQAYLESRKK---LTALGPATAVAGAG---VHASSSHDLGIRD-HLKQSLQKARKQPHIPSYQQINCVDSIIRYLESCATSALKRKCESLSITTSSSSSTSEEDKPTSAAHENTDEAALDAARALDSQVSAGSATTAAVVGAPLTDITISTEAMSVVSVTSQCSYSSTIVHVPQPESEVTALEDAPMGSEPADSAPAPASPAPDSGSASTSQEELLVLGLTKEVLSAHTQKEEQQFVDRFRHRILQSPYSSYLQQDN-------------SSNAHSHHRGDVVRQPNKHKRPKPEDSSDSYECSQPGNYWSLPGPTAAPHSSWPSSESSQPPPSNIGFVPPMAVPMQTP---PYFNIIGADQQPVMLQPDPGVQNLQPMT-PMMVVLLP--SFPMYPPNNGMYFPMAAPGVVPYNIGGFVPPGAPMPAEAPLQGHNLESAGVGVPAEPDSIPEPWFGEDLDAAQP--TALFSSSRSSSPIQLNLLQEELTKPSEAQTSTNADSLQEPHTKTDDARSECGHQDAHSSSSEMLDQLLQEDARSGTGSNASGSGSGESGG---------------------------------------------SLGSGSGLGSNGTSTSHTGSSNSSKYFASND-SSDTSRKARKSAEAQERERSGFKKHVDDPLWSMIKQTPEPVMLTYQISSRDQAQVLQEDREKLILMQPMQPWFTSDQKKELAEVHPWIQQNTVPQEINTQGCVSCNTIEPNKKLNLQTDSPNPPDISCPQDCPPQENRPDTDT", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P07663-1", "uniprot_id": "PER_DROME", "id": "P07663-1", "name": "Period circadian protein", "aln": "------MEGGESTESTHNTKVSDSAYSNSCSNSQSQRSGSSKSRLSGSHSSGSSGYGGKPSTQASSSDMIIKRNKDKSRKKKKNKGAGQGAGQAQTLISASTSLEGRDEEKPRPSGTGCVEQQICRELQDQQHGEDHSEPQAIEQLQQEEEEDQSGSESEADRVEGVAKSEAAQSFPIPSPLSVTIVPPSMGGCGGVGHAAGLDSGLAKFDKTWEAGPGKLESMTGVGAAAAGTGQRGERVKEDSFCCVISMHDGIVLYTTPSITDVLGYPRDMWLGRSFIDFVHLKDRATFASQITTGIPIAESRGSVPKDAKSTFCVMLRRYRGLKSGGFGVIGRPVSYEPFRLGLTFREAPEEARPDNYMVSNGTNMLLVICATPIKSSYKVPDEILSQKSPKFAIRHTATGIISHVDSAAVSALGYLPQDLIGRSIMDFYHHEDLSVMKETYETVMKKGQTAGASFCSKPYRFLIQNGCYVLLETEWTSFVNPWSRKLEFVVGHHRVFQGPKQCNVFEAAPTCKL-----KISEEAQSRNTRIKEDIVKRLAETVSRPSDTVKQEVSRRCQALASFMETLMDEVSRADLKLELPHENELTVSERDSVMLGEISPHHDYYDSKSSTETPPSYNQLNYNENLLRFFNSKPVTAPAELDPPKTEPPEPRGTCVSGASGPMSPVHEGSGGSGSSGNFTTASNIHMSS-----VTNTSIAGTGGTGTGTGTGTGTGTGTGTGTGTGTGTGTG-------TGTGTGTGTGTGNGTNSGTGTGTASSSKGG-------------SAAIPPVTLTESLLNKHNDEMEKFMLKKHRESRGRTGEKSKKSANDTLKMLEYSGPGHGIKRGGSHSWEG------EANKPKQQLTLGTDAIKGAAGSAGGAVGTGGVGSGGAGVAGGGGS-----GTGVAGTPEGRATTTSGTGTPGGAGGGGGAGAAAAAGASSSVGSSTPGPSSYPTCTQNINLWPPFSVGITPPVHSTHTAMAQSSFSSAGLFPTFYYIPASLTPTSPTRSPRMHKHPHKGGTDMPTTSQQAAAAAAQAMPLQYMAGVMYPHPSLFYTHPAAAAATAMMYQPMPFPGMANALQIPE--------RPLGSQSAYNKSVYTTTPASMTKKVPG-------------------------------------------------------------------------------AFHSVTTPAQVQRPSSQSASVKTEPGSSAAVSDPCKKEVPDSSPIPSVMGDYNSDPPCSSSNPANNKKYTDSNGNSD-------DMDGSSFSSFYSSFIKTTDGSESPPDTEKDPKHRKLKSMSTSES--------KIMEHPEEDQTQHGDG---------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *. .* * .. : . ... . : : .. *: : * .:: .. :: : :: * : . * . . :: * :. *:* *:*: .* ::: : . : :* : . . *:::: :* .* :: : :. . . : *. : : ** :.***: : .. : : : . * *.*:.* :.:: *: *:. :: .**. **. **:******* *:: * :* :* :..::* . .* .* ** *** *: *::.*:**:******: *::*:*:* .* : :** : . .: * : : : :. . ... .:* : :. :: :.*: . .:.: .. * : . . . . : : . : : . :. .. : : . : . : : ** . . . . : . : .: *.* .. .. . : . : : . :*.::. * :: .* : . . : * : . . .:.. .. . :. : . . *: . . .: * .. . . : : : ::.::. :: : :. *. .. :: : : :: :. ... :* :. . . . .: . * . .: ..* . *: . : . . :: . : : :. ", "identical_positions": 91, "similar_positions": 281, "identity": "6.61%" }, { "cls_id": "homologset.agr.MGI:1277137", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JHU6-1", "uniprot_id": "STMN3_RAT", "id": "Q9JHU6-1", "name": "Stathmin-3", "aln": "-----------------------------------------------------------------------------------------------MASTVSAYKEKMKELSVLSLICSCFYSQPHPNTIYQYGDMEVKQLDKRASGQSFEVILKSPSDLSPESP-VLSSPPKRKDASLEELQKRLEAAEERRKTQEAQVLKQLAERREHEREVLHKALEENNNFSPLAEEKLNYKMELSKEIREAHLAALRERLR----------------------------------------------------------------------------EKELHAAEVRRNKEQREEMSG--------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70166-1", "uniprot_id": "STMN3_MOUSE", "id": "O70166-1", "name": "Stathmin-3", "aln": "-----------------------------------------------------------------------------------------------MASTVSAYKEKMKELSVLSLICSCFYSQPHPNTIYQYGDMEVKQLDKRASGQSFEVILKSPSDLSPESP-VLSSPPKRKDASLEELQKRLEAAEERRKTQEAQVLKQLAERREHEREVLHKALEENNNFSRLAEEKLNYKMELSKEIREAHLAALRERLR----------------------------------------------------------------------------EKELHAAEVRRNKEQREEMSG--------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NZ72-1", "uniprot_id": "STMN3_HUMAN", "id": "Q9NZ72-1", "name": "Stathmin-3", "aln": "-----------------------------------------------------------------------------------------------MASTISAYKEKMKELSVLSLICSCFYTQPHPNTVYQYGDMEVKQLDKRASGQSFEVILKSPSDLSPESP-MLSSPPKKKDTSLEELQKRLEAAEERRKTQEAQVLKQLAERREHEREVLHKALEENNNFSRQAEEKLNYKMELSKEIREAHLAALRERLR----------------------------------------------------------------------------EKELHAAEVRRNKEQREEMSG--------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FFU5-1", "uniprot_id": "E7FFU5_DANRE", "id": "E7FFU5-1", "name": "Stathmin", "aln": "-----------------------------------------------------------------------------------------------MDSTLSAYSDKLREMSVLSLICSCLYNQPHPNTFGQFEDMEVKSLNKRASGQAFEVILKSPTDPSPERPQTLALPPQRKEPSLGELQRRLEAAEARRRSQEKQVLKQLAEKREREKEVLTKAQEVNNNYSKKTEEKLNHKMEMITENRMARLNALKQRLR----------------------------------------------------------------------------EKEIHAEEVRKNKELNTDLSG--------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9NEA1-1", "uniprot_id": "M9NEA1_DROME", "id": "M9NEA1-1", "name": "", "aln": "MGCNFSALPTKCKGCGQIRADFDRRYGCSECGSEVMYCGQCFDEGRNQHTETHKDDRRIKIIYHRSFLDKFFSGEKLLNGDASKSYNCVFCKKRFSAEELQLHLSEMHSNPADASALTVMLERMRQEDLENRIATEIRCQEKSRGGLSYEVILAEP---APNVAVPKRPVTPGKNVSVEEIEQKLKAAEERRISLEAKKMADISTKLAKVEEATRKKDEITNEFITQTKEQLESKMELHVEKREAIISDMKEKLKIHAQDIEKTRETLEQQKANEQKAIEEKLKIAQSLRDENIKKMLDRLKEHNTIKIAEIKSQNDQLECQKIEEKARIYENKLFAAEQKREKELQKKIEKVQKLERRAELVRQNKAQAQDLDGQQSAIASSG", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :. : .:::. .. : : : : : : . : *:: :* .* ::**** .* :*: . . *: *: *::::*:*** ** : * : : ::: : : .*. * * .*:: ::*:*: ***: * * * : ::::*: *:::.* * :::** . .:. ", "identical_positions": 37, "similar_positions": 72, "identity": "9.64%" }, { "cls_id": "homologset.agr.MGI:1277143", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q561R7-1", "uniprot_id": "TF2H3_RAT", "id": "Q561R7-1", "name": "General transcription factor IIH subunit 3", "aln": "--------MAADEDE-------LNLLVIIVDTNPIWWGKQALKESQF-TLSKCMDAVMVLANAHLFMNRSNQLAVIASHIQESRFLYPGKNGRLGDFFGDPGNALPDCNPSGSKDGKYELLTAANEVIAEEIKDLMTKS--DIKGQHTETLLAGSLAKALCYIHRASKAVKDNQEMKSRILVIKA----AEDSALQYMNFMNVIFAAQKQNILIDACVLD--SDSGLLQQACDITGGLYLKVPQMPSLLQYLLWVFLPDQDQRSQLILPPPIHVDYRAACFCHRSLIEIGYVCSVCLSIFCNFSP--ICTTCETAFKISLPPVLKAK------KKKQKVSL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VD76-1", "uniprot_id": "TF2H3_MOUSE", "id": "Q8VD76-1", "name": "General transcription factor IIH subunit 3", "aln": "--------MAADEDE-------LNLLVIIVDTNPIWWGKQALKESQF-TLSKCMDAVMVLANSHLFMNRSNQLAVIASHIQESRLLYPGKNGGLGDFFGDPGNALPDCNPSGSKDGKYELLTVANEVIAEEIKDLMTKS--DIKGQHTETLLAGSLAKALCYIHRVNKAVKDNQEMKSRILVIKA----AEDSALQYMNFMNVIFAAQKQNILIDACVLD--SDSGLLQQACDITGGLYLKVPQMPSLLQYLLWVFLPDQDQRSQLILPPPIHVDYRAACFCHRSLIEIGYVCSVCLSIFCNFSP--ICTTCETAFKISLPPVLKAK------KKKQKVSL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13889-1", "uniprot_id": "TF2H3_HUMAN", "id": "Q13889-1", "name": "General transcription factor IIH subunit 3", "aln": "--------MVSDEDE-------LNLLVIVVDANPIWWGKQALKESQF-TLSKCIDAVMVLGNSHLFMNRSNKLAVIASHIQESRFLYPGKNGRLGDFFGDPGNP-PEFNPSGSKDGKYELLTSANEVIVEEIKDLMTKS--DIKGQHTETLLAGSLAKALCYIHRMNKEVKDNQEMKSRILVIKA----AEDSALQYMNFMNVIFAAQKQNILIDACVLD--SDSGLLQQACDITGGLYLKVPQMPSLLQYLLWVFLPDQDQRSQLILPPPVHVDYRAACFCHRNLIEIGYVCSVCLSIFCNFSP--ICTTCETAFKISLPPVLKAK------KKKLKVSA-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VPX4-1", "uniprot_id": "Q9VPX4_DROME", "id": "Q9VPX4-1", "name": "General transcription factor IIH subunit 3", "aln": "--------MEADQAASKEAESCIDLLVIVLDTNP---SQHFVRQNPQ-NLTQILEAVIAFGNAHLMQKAQNKLAVVSCSHHATNFLYPLPRRQV---------------ELRQVDGQYEAFNLVEKTVKQQLGSILMNA--PRLSAPCESLLAGSMSMALCYISRLQRNLAPGVKMHSRILVVTG----SNECASQYMTFMNVFFTAQKLGITIDTCALD--KTLSLLQQGCDITSGQFLKVTQLDGLLQYLLWVFLPAPQIRHKLVLPPPPKVDYRASCFCHRELIDIGYVCSVCLSVFCKYSP--ICTTCHTIFKNPGPLPIKGK------KKKKTDKQM", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12004-1", "uniprot_id": "TFB4_YEAST", "id": "Q12004-1", "name": "General transcription and DNA repair factor IIH subunit TFB4", "aln": "MDAISDPTFKHARSRKQVTEESPSLLTVIIEIAPKLWTTFDEEGNEKGSIIKVLEALIVFLNAHLAFNSANKVAVIAAYSQGIKYLYPESTSALKASESENKTR---SDLKIINSDMYRRFRNVDETLVEEIYKLFELEKKQIEQNSQRSTLAGAMSAGLTYVNRISKESVTTS-LKSRLLVLTCGSGSSKDEIFQYIPIMNCIFSATKMKCPIDVVKIGGSKESTFLQQTTDATNGVYLHVESTEGLIQYLATAMFIDPSLRPIIVKPNHGSVDFRTSCYLTGRVVAVGFICSVCLCVLSIIPPGNKCPACDSQFDEHVIAKLKRKPVVPRLKAKKKVTKP", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . .**.:::: * . . .: : ::*::.: *:** : *::**::. : . *** : .. *. : .::.: ::: .:: .: ***::: .* *: * .: ::**:**:. ::: **: :** :*:* * **. :. . :*** * *.* :*:* . .*:*** .:: . * :: * **:*::*: :: :*::*****.::. .* *.:*.: *. :* * * * . . ", "identical_positions": 65, "similar_positions": 104, "identity": "19.01%" }, { "cls_id": "homologset.agr.MGI:1277150", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZUC8-1", "uniprot_id": "A0A8I5ZUC8_RAT", "id": "A0A8I5ZUC8-1", "name": "", "aln": "MPEAGFQATNAFTECKFTCTSGKCLYLGSLVCNQQNDCGDNSDEENCLLVTEHPPPGIFNSELEFAQVLIIVVVVTVMVVVVVCLLNHYKVSTRSFINRPNQSQRQEDGLQPEGSLWPSDSSVQRPGASEIMCAPRGRDRFTTPSFIQRDPFSRFQPTYPYVQHEIDLPPTISLSDGEEPPPYQGPCTLQLRDPEQQMELNRESVRAPPNRTIFDSDLIDISMYNGG--PCPPSSHSGISAATCSSNGRMEGPPPTYSEVMGH-YPGTSFFHHQHSN-----AHRGSRQQFQPNNSEGTIVPIKGKDRKPGDLV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BWJ4-1", "uniprot_id": "LRAD4_MOUSE", "id": "Q8BWJ4-1", "name": "Low-density lipoprotein receptor class A domain-containing protein 4", "aln": "MPEAGFQATNAFTECKFTCTSGKCLYLGSLVCNQQNDCGDNSDEENCLLVTEHPPPGIFNSELEFAQILIIVVVVTVMVVVVVCLLNHYKVSTRSFINRPNQSQRQEDGLQPEGSLWPSDSSVQRPGASEIMCAPRGRDRFTTPSFIQRDPFSRFQPTYPYVQHEIDLPPTISLSDGEEPPPYQGPCTLQLRDPEQQMELNRESVRAPPNRTVFDSDLIDISMYNGG--PCPPSSHSGISAATCSSNGRMEGPPPTYSEVMGH-YPGTSFFHHQHSN-----THRGSRPQFQPNNSEGTIVPIKGKDRKPGDLV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15165-1", "uniprot_id": "LRAD4_HUMAN", "id": "O15165-1", "name": "Low-density lipoprotein receptor class A domain-containing protein 4", "aln": "MPEAGFQATNAFTECKFTCTSGKCLYLGSLVCNQQNDCGDNSDEENCLLVTEHPPPGIFNSELEFAQIIIIVVVVTVMVVVIVCLLNHYKVSTRSFINRPNQSRRREDGLPQEGCLWPSDSAAPRLGASEIMHAPRSRDRFTAPSFIQRDRFSRFQPTYPYVQHEIDLPPTISLSDGEEPPPYQGPCTLQLRDPEQQMELNRESVRAPPNRTIFDSDLIDIAMYSGG--PCPPSSNSGISASTCSSNGRMEGPPPTYSEVMGH-HPGASFLHHQRSN-----AHRGSRLQFQQNNAESTIVPIKGKDRKPGNLV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AJA1-1", "uniprot_id": "A0A8M3AJA1_DANRE", "id": "A0A8M3AJA1-1", "name": "", "aln": "MQEADLPATNAFTECRFLCTNGRCLNVGSQVCDQLNHCGDNSDEEHCPISTQHPASAIFSSELEFVQIVIIIVVMTVMVVVVVCLLNHYKLTTWSFLSRPSQAQSQDLSLQPEGSLWPSDN-GLRQGASEVVYAPQPRDRFTAPTFMQHNRFRRFQPTYPYLQHEIDLPPTISLSDGEEPPPYQGPCTLQLRDPEQQLELNRESVRAPPNRTIFDSDLIDMHSSAGGGGPRPPSSNSGISAASSSTHGRMEGPPPAYSQVIGQ-HSGIVLYLQQHSNNPPVTVQTPLTGRTDPNSTESTIVLSK--DPLREELV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1QYX0-1", "uniprot_id": "F1QYX0_DANRE", "id": "F1QYX0-1", "name": "", "aln": "MQAADYPATNNNTECKFHCTNGRCLKLLSLICNHLNECGDNSDEEHCPAAVP-PPPDTIQTELEFVQIIIIIVVMTVMVVVIICLLNHYRLSAWAFLTRHSQARRREEGMQPDGCAWPTDSLVTQQGATEVMYGPRSGERFNPPSFMQRDRFSRFQPTYPYLQQDIHLPPTICLSDGEELPPYKGPCTLQLRDPEQQLELSRASVRAPPNRTIFDSDLIDVYVHGGG--PRPPSSNSGKSAS----NSHVEGPPPTYSEVMGQTYPGSASFLHQHSNNAPPSNQRTASRSGQPGASTTLFVKVK--DSRRDKPV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* *. *** ***:* **.*:** : * :*:: *.********:* . *.. :.:****.*::**:**:******::******:::: :*:.* .*:: :: .: :*. **:*. : **:*:: .*: :**..*:*:*:: * ********:*::*.*****.****** ***:*************:**.* *********:*******: ** * ****:** **: :.::*****:**:*:*: :.* :*:** : : . : :* * * . *", "identical_positions": 149, "similar_positions": 84, "identity": "47.45%" }, { "cls_id": "homologset.agr.MGI:1277151", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O55042-1", "uniprot_id": "SYUA_MOUSE", "id": "O55042-1", "name": "Alpha-synuclein", "aln": "MDVFMKGLSKAKEGVVAAAEKTKQGVAEAAGKTKEGVLYVGSKTKEGVVHGVTTVAEKTKEQVTNVGGAVVTGVTAVAQKTVEGAGNIAAATGFVKKDQMGKGEEGYPQEGILEDMPVDPGSEAYEMPSEEGYQDYEPEA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P37377-1", "uniprot_id": "SYUA_RAT", "id": "P37377-1", "name": "Alpha-synuclein", "aln": "MDVFMKGLSKAKEGVVAAAEKTKQGVAEAAGKTKEGVLYVGSKTKEGVVHGVTTVAEKTKEQVTNVGGAVVTGVTAVAQKTVEGAGNIAAATGFVKKDQMGKGEEGYPQEGILEDMPVDPSSEAYEMPSEEGYQDYEPEA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P37840-1", "uniprot_id": "SYUA_HUMAN", "id": "P37840-1", "name": "Alpha-synuclein", "aln": "MDVFMKGLSKAKEGVVAAAEKTKQGVAEAAGKTKEGVLYVGSKTKEGVVHGVATVAEKTKEQVTNVGGAVVTGVTAVAQKTVEGAGSIAAATGFVKKDQLGKNEEGAPQEGILEDMPVDPDNEAYEMPSEEGYQDYEPEA", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****************************************************:*********************************.************:**.*** *************..******************", "identical_positions": 133, "similar_positions": 6, "identity": "95.0%" }, { "cls_id": "homologset.agr.MGI:1277152", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3B8P0-1", "uniprot_id": "PARL_RAT", "id": "Q3B8P0-1", "name": "Presenilin-associated rhomboid-like protein, mitochondrial", "aln": "MALYSWVQRGWRCGQTWAPLLGG-GYRELSATQAR-QLLGRRFNLLLQQKCGFRKAPRKVEPRRSDTGSSGEAYKRSALIPPLEETVFYPS--PYPVRTLLKPFFFTVGFTGCAFGSAAIWQYESLKSRVQSYFDGIKADWLDSIRP-----------QKEGNLRK-------EINKWWNSLSDGQRTVTGIIAANALVFCLWRVPSLHRTMIRYFTSNPASKVLCSPMLLSTFSHFSLFHMAANMYVLWSFSTSIVNILGQEQFVAVYLSAGVISNFVSYVCKVAT--GRYGPSLGASGAIMTVLAAVCTKIPEGRLAIIFLPVFTFTAGNALKAIIAMDTAGMILGWKFFDHAAHLGGALFGIWYITYGHELIWKNREPLVKIWHEIRTNGPKK---GGGSK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5XJY4-1", "uniprot_id": "PARL_MOUSE", "id": "Q5XJY4-1", "name": "Presenilin-associated rhomboid-like protein, mitochondrial", "aln": "MALQGWVQRGWRCGPAWAPPLGG-GYRELSATQAP-RLLGRRFNLFVQQKCGFRKAPRKVEPRRSDTGSSGEAYKRSALIPPLEETVFYPS--PYPIRTLVKPFFFTIGFTGCAFGSAAIWQYESLKSRVQSYFDGIKADWLDSIRP-----------QKEGNLRK-------EINKWWNSLSDGQRTVTGIIAANALVFCLWRVPSLQRTMIRYFTSNPASKVLCSPMLLSTFSHFSLFHMAANMYVLWSFSSSIVNILGQEQFVAVYLSAGVISNFVSYVCKVAT--GRYGPSLGASGAIMTVLAAVCTKIPEGRLAIIFLPVFTFTAGNALKAIIAMDTAGMILGWKFFDHAAHLGGALFGIWYITYGHELIWKNREPLVKIWHEIRTNGPKK---GGGSK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H300-1", "uniprot_id": "PARL_HUMAN", "id": "Q9H300-1", "name": "Presenilin-associated rhomboid-like protein, mitochondrial", "aln": "MAWRGWAQRGWGCGQAWGASVGGRSCEELTAVLTPPQLLGRRFNFFIQQKCGFRKAPRKVEPRRSDPGTSGEAYKRSALIPPVEETVFYPS--PYPIRSLIKPLFFTVGFTGCAFGSAAIWQYESLKSRVQSYFDGIKADWLDSIRP-----------QKEGDFRK-------EINKWWNNLSDGQRTVTGIIAANVLVFCLWRVPSLQRTMIRYFTSNPASKVLCSPMLLSTFSHFSLFHMAANMYVLWSFSSSIVNILGQEQFMAVYLSAGVISNFVSYVGKVAT--GRYGPSLGASGAIMTVLAAVCTKIPEGRLAIIFLPMFTFTAGNALKAIIAMDTAGMILGWKFFDHAAHLGGALFGIWYVTYGHELIWKNREPLVKIWHEIRTNGPKK---GGGSK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q58EK4-1", "uniprot_id": "PARLA_DANRE", "id": "Q58EK4-1", "name": "Presenilin-associated rhomboid-like protein A, mitochondrial", "aln": "MAWRSCFMKWTQINSINASSLCP---------------KSTRLNIHPQQRCGFRKTERPSESKKGVQETEAEAGGHNRAVPP--KPVPPLP--PRRPHQLFRPLVFTVGFTGCSFGAAAILQYESVKSRVQLAIEEAKEEKRDTLLEGHDTTYWHNWWNQLSNFQKQVILLISAVDDFWSGLSEGQKTVTGIIALNTVVLCCWRVPAMQRFLVKYFTSNPASKTRCLPMVLSSFSHYSVIHMVVNMYVLWTFSSSIVSLLGREQFLALYLSGGVISTFVSYVFKTAT--GRLGPSLGASGSIMTVLAAVCTKIPEAKLGIVLLPVISFSAGNALKALVALDIAGLVLGWRFFDHAAHLGGALFGVWYIGYGHELIWRKREPLIKFWHELRNMSPGRPGPGGGGG", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z8R8-1", "uniprot_id": "PARL_DROME", "id": "A1Z8R8-1", "name": "Presenilins-associated rhomboid-like protein, mitochondrial", "aln": "MLMSRALCR------SWLPQVAR--------------------RCHANVNVPILRINSGHPAARSCRQIHSNRKQSSNLKPTTGEPAAAEQNTPVPVNNVIKAVAFTGAFTVGCFAGATILEYENTRSLILEKARQARFGWWQSRSLADR--------DYWTQIKQ-------DIRRHWDSLTPGDKMFAPILLCNLVAFAMWRVPALKSTMITYFTSNPAAKVVCWPMFLSTFSHYSAMHLFANMYVMHSFANAAAVSLGKEQFLAVYLSAGVFSSLMSVLYKAAT--SQAGMSLGASGAIMTLLAYVCTQYPDTQLSILFLPALTFSAGAGIKVLMGIDFAGVVMGWKFFDHAAHLGGAMFGIFWATYG-AQIWAKRIGLLNYYHDLRRTKQK---------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53259-1", "uniprot_id": "PCP1_YEAST", "id": "P53259-1", "name": "Rhomboid protein 1, mitochondrial", "aln": "MSGVSSVMLG-----------------------------------LRPATRIFFRSNISVSPSRTFVSYIGRSQSTSILKNAPNLEDNVTNLQKIIPKRFFSQTSILKSRWKPIFNEETTNRYVRLNRFQQYQQQRSGGNPLGSMTILG--------LSLMAGIYFGSPYLFEHVPPFTYFKTHPKNLVYALLGINVAVFGLWQLPKCWRFLQKYMLLQKDYVTSKISIIGSAFSHQEFWHLGMNMLALWSFGTSLATMLGASNFFSLYMNSAIAGSLFSLWYPKLARLAIVGPSLGASGALFGVLGCFSYLFPHAKILLFVFPVPG-GAWVAFLASVAWNAAGCALRWGSFDYAAHLGGSMMGVLYGWYISKAVEKQRQRRLQAAGRWF--------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : : . : .. . . . .. : . * : .* . : . : : : .. . :: * .: *::* : *: : . .:. *:*** . *: ** .: :*..: . ** .:*.::*:...: ..:.* : . * ******::: :*. .. *. :: :..:* * .: . :. : ** : * **:******:::*: : * : :* :: ", "identical_positions": 45, "similar_positions": 94, "identity": "11.14%" }, { "cls_id": "homologset.agr.MGI:1277162", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q64261-1", "uniprot_id": "CDK6_MOUSE", "id": "Q64261-1", "name": "Cyclin-dependent kinase 6", "aln": "MEKDSLSRADQQYECVAEIG----EGAYGKVFKARDLKNGGR----FVALKRVRVQTSEEGMPLSTIREVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIK----DMMFQLLRGLDFLHSHRVVHRDLKPQNILVTS-----SGQIKLADFGLARIYS--------FQMALTSVVVTLWYRAPEVLLQS-SYATPVDLWSVGCIFAEMFRRKP---------LFRGSSDVDQLG-------KILDIIGLPGEEDWPRDVALPRQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYGALNHPYFQDLERYKDNLNSH--LPSNQSTSELNTA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1MA87-1", "uniprot_id": "F1MA87_RAT", "id": "F1MA87-1", "name": "cyclin-dependent kinase", "aln": "MEKDSLSRADQQYECVAEIG----EGAYGKVFKARDLKNGGR----FVALKRVRVQTGEEGMPLSTIREVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIK----DMMFQLLRGLDFLHSHRVVHRDLKPQNILVTS-----SGQIKLADFGLARIYS--------FQMALTSVVVTLWYRAPEVLLQS-SYATPVDLWSVGCIFAELFRRKP---------LFRGSSDVDQLG-------KILDVIGLPGEEDWPRDVALPRQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYGALNHPYFQDLERYKDNLHSH--LSSSQSTSELNTA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q00534-1", "uniprot_id": "CDK6_HUMAN", "id": "Q00534-1", "name": "Cyclin-dependent kinase 6", "aln": "MEKDGLCRADQQYECVAEIG----EGAYGKVFKARDLKNGGR----FVALKRVRVQTGEEGMPLSTIREVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIK----DMMFQLLRGLDFLHSHRVVHRDLKPQNILVTS-----SGQIKLADFGLARIYS--------FQMALTSVVVTLWYRAPEVLLQS-SYATPVDLWSVGCIFAEMFRRKP---------LFRGSSDVDQLG-------KILDVIGLPGEEDWPRDVALPRQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYFQDLERCKENLDSH--LPPSQNTSELNTA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "I3IT74-1", "uniprot_id": "I3IT74_DANRE", "id": "I3IT74-1", "name": "cyclin-dependent kinase", "aln": "MDKE---SSTQQYEPVAEIG----EGAYGKVYKARDLKNGGR----FVALKRVRVQTEEEGMPLSTIREVAVLRQLESFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLEKAPDPGVPPETIK----DMMYQLLQGLDFLHSHRVVHRDLKPQNILVTS-----GGQIKLADFGLARIYS--------FQMALTSVVVTLWYRAPEVLLQS-SYATPVDLWSVGCIFAEMFRRRP---------LFRGNSDVDQLG-------KIFDVVGVPSPEDWPQEVGLPQSAFSPRPAQPIENLVPDMDELGKSLLLRFLSFNPSRRISAYDALSHLYFQSLDSTSKSLYAQP-FPSKKPSLEERAA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P43568-1", "uniprot_id": "CAK1_YEAST", "id": "P43568-1", "name": "Serine/threonine-protein kinase CAK1", "aln": "MKLDSIDITHCQLVKSTRTARIYRSDTYAIKCLALDFDIPPHNAKFEVSILNKLGNKCKHILPLLESKATDNNDLLLLFPFEEMN-LYEFMQMHYKRDRRKKNPYYDLLNPSIPIVADPPVQKYTNQLDVNRYSLSFFRQMVEGIAFLHENKIIHRDIKPQNIMLTNNTSTVSPKLYIIDFGISYDMANNSQTSAEPMDSKVTDISTGIYKAPEVLFGVKCYDGGVDVWSLLIIISQWFQRETSRMGHVPAMIDDGSDDMNSDGSDFRLICSIFEKLGIPSIQKW-EEVAQHGSVDAFVGMFGADGDGKYVLDQEKDVQISIVERNMPRLDEIADVKVKQKFINCILGMVSFSPNERWSCQRILQELEKP", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. : : * :. . ..:*. * *:. : *:: . :. :. :** : . * * . :: *::. : . . * . :: :: .:. : : . :: .:: *::.*: ***.::::***:*****::*. . :: : ***:: : : .: : * *:*****: .* **:**: *::: *:*.. : *..*::. * .*:: :*:*. :.* .:*. .. : : : *.: : : * .: . .. : * . .: .: . .: * . .", "identical_positions": 56, "similar_positions": 125, "identity": "15.14%" }, { "cls_id": "homologset.agr.MGI:1277163", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q2NKI2-1", "uniprot_id": "VAX1_MOUSE", "id": "Q2NKI2-1", "name": "Ventral anterior homeobox 1", "aln": "MFGKPDKMDVRCHSDTEAARVSKNAHKESREIKGAEGSLPAAFLKEPQGAFSGSGASEDCNKSKSNSSADPDYCRRILVRDAKGSIREIILPKGLDLDRPKRTRTSFTAEQLYRLEMEFQRCQYVVGRERTELARQLNLSETQVKVWFQNRRTKQKKDQGKDSELRSVVSETAATCSVLRLLEQGRLLSPPGLPALLPPCATGALGSALRGPSLPALGAGAAAGSAAAAAAAAAATAPGPAGAASQHQPAVGGAPGPGPAGPGGLHAGAPTASHGLFSLPVPSLLGSVASRLSSAPLTMAGSLAGNLQELSARYLSSSAFEPYSRTNNKEGAEKKALD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9JM00-1", "uniprot_id": "VAX1_RAT", "id": "Q9JM00-1", "name": "Ventral anterior homeobox 1", "aln": "MFGKTDKMDVRCHSDTEAARVSKNAHKESREIKGAEGSLPAAFLKEPQGAFSASGASEDCNKSKSNSSADPDYCRRILVRDAKGSIREIILPKGLDLDRPKRTRTSFTAEQLYRLEMEFQRCQYVVGRERTELARQLNLSETQVKVWFQNRRTKQKKDQGKDSELRSVVSETAATCSVLRLLEQGRLLSPPGLPALLPPCATGALGSALRGPSLPALGAGAAAG--SAAAAAAAATAPGPAGAASQHPPAVGGAPGPGPAGPGGLHAGAPTASHGLFSLPVPSLLGSVASRLSSAPLTMAGSLAGNLQELSARYLSSSAFEPYSRTNNKEGAEKKALD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5SQQ9-1", "uniprot_id": "VAX1_HUMAN", "id": "Q5SQQ9-1", "name": "Ventral anterior homeobox 1", "aln": "MFGKPDKMDVRCHSDAEAARVSKNAHKESRESKGAEGNLPAAFLKEPQGAFSASGAAEDCNKSKSNSAADPDYCRRILVRDAKGSIREIILPKGLDLDRPKRTRTSFTAEQLYRLEMEFQRCQYVVGRERTELARQLNLSETQVKVWFQNRRTKQKKDQGKDSELRSVVSETAATCSVLRLLEQGRLLSPPGLPALLPPCATGALGSALRGPSLPALGAGAAAG----SAAAAAAAAPGPAGAASPHPPAVGGAPGPGPAGPGGLHAGAPAAGHSLFSLPVPSLLGSVASRLSSAPLTMAGSLAGNLQELSARYLSSSAFEPYSRTNNKEGAEKKALD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q801E0-1", "uniprot_id": "VAX1_DANRE", "id": "Q801E0-1", "name": "Ventral anterior homeobox 1", "aln": "-------MEVRYSQDSESGMLLKNGLKEGKEGKDSQGSISKTFLKDQQESFSPSGAVENCEKSRASS-GDPDYCRRILVRDAKGSIREIILPKGLDLDRPKRTRTSFTAEQLYRLEMEFQRCQYVVGRERTELARQLNLSETQVKVWFQNRRTKQKKDQGKDSELRSVVSETAATCSVLRLLEQGRLLTPPGLPGLLPHCGSSSLGSALRGPSLGITANGGSSS-----SSRSSAGSSGTAGGSPPLPTVTSSGTVTG-------LQGSPPA-HGLFSFPMPSLLGSVASRISSTPLGMAGSLAGNLQELSARYLCSSAFEPYSRTNGKEALDKKVLE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:** .*:*:. : **. **.:* *.::*.:. :***: * :** *** *:*:**::.* .***********************************************************************************************************************:*****.*** *.:.:********** . *.::. :: ::* :.*.**.:. ....... .* *:*.* *.***:*:**********:**:** *****************.***********.**. :**.*:", "identical_positions": 225, "similar_positions": 66, "identity": "66.57%" }, { "cls_id": "homologset.agr.MGI:1277166", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A0B6-1", "uniprot_id": "A0A8I6A0B6_RAT", "id": "A0A8I6A0B6-1", "name": "", "aln": "------------------------------------------------MTAPEKPVKQEEMAALDVD------SGGGGGGHGEYLQQQ-------------------QQQQQHGNGAAAAAAAQDTQPSPLALLAATCSKIGPPS----------PGDDEEEA--AAAAG-------VPAAAAGATGDLASAQLGGAPNRWEVLSATPTTIKDEAGNLVQIPGAATSSGQYVLPLQNLQNQ-QIFSVAPGSD-----SSNGTVSNVQYQVIPQIQSTDAQQVQIGFTGSSDNGGINQESSQIQIIPGSNQTLLASGTPPANIQNLIPQT-------GQVQ-VQGVAIGGSSFPG----QTQVVANVPLGLPGNITFVPIN---SVDLDSLGLSGSSQTMTAGINADGHLINTGQAMDSSDNSERTGERVSPDVNETNADTDLFVPTSSSSQ---LPVTIDSTGILQQNTNSLTTTSGQVHSSDLQGNYIQSPVSEETQAQNIQVSTAQPVVQHLQLQDSQQPTSQAQIVQGITPQTIHGVQASGQNISQQALQNLQLQLNPGTFLIQAQTVTPSGQITWQTFQVQGVQNLQNLQIQNT---AAQQITLTPVQTLTLGQVAAGGALTSTPVSLSTGQLPNLQTVTVNSIDSTGIQLHPGENADSPADIRIKEEEPDPEEWQLSGDSTLNTNDLTHLRVQVVDEEGDQQHQEG----------KRLRRVACTCPNCKEGGGRGTNLGKKKQHICHIPGCGKVYGKTSHLRAHLRWHSGERPFICNWMFCGKRFTRSDELQRHRRTHTGEKKFVCPECSKRFMRSDHLAKHIKTHQNKK-------------------------------------VIHSSSTVLASVEAGRDDALITAGGTTLILANIQQGSVSGIGTVNASATSNQDILTNTEIPLQLVTVSGNETME------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70494-1", "uniprot_id": "SP3_MOUSE", "id": "O70494-1", "name": "Transcription factor Sp3", "aln": "------------------------------------------------MTAPEKPVKQEEMAALDVD------GGGGGGGHGEYLQQQ-------------------QQQQQQHGNGAAAAAAQDTQPSPLALLAATCSKIGPPS----------PGDDDEEAAVAAAAG-------VPAAAAGATGDLASAQLGGAPNRWEVLSATPTTIKDEAGNLVQIPGAATSSGQYVLPLQNLQNQ-QIFSVAPGSD-----SSNGTVSNVQYQVIPQIQSTDAQQVQIGFTGSSDNGGINQENSQIQIIPGSNQTLLASGTPPANIQNLIPQT-------GQVQ-VQGVAIGGSSFPG----QTQVVANVPLGLPGNITFVPIN---SVDLDSLGLSGSSQTMTAGINADGHLINTGQAMDSSDNSERTGERVSPDVNETNADTDLFVPTSSSSQ---LPVTIDSTGILQQNTNSLTTTSGQVHSSDLQGNYIQSPVSEETQAQNIQVSTAQPVVQHLQLQDSQQPTSQAQIVQGITPQTIHGVQASGQNISQQALQNLQLQLNPGTFLIQAQTVTPSGQITWQTFQVQGVQNLQNLQIQNT---AAQQITLTPVQTLTLGQVAAGGALTSTPVSLSTGQLPNLQTVTVNSIDSTGIQLHPGENADSPADIRIKEEEPDPEEWQLSGDSTLNTNDLTHLRVQVVDEEGDQQHQEG----------KRLRRVACTCPNCKEGGGRGTNLGKKKQHICHIPGCGKVYGKTSHLRAHLRWHSGERPFICNWMFCGKRFTRSDELQRHRRTHTGEKKFVCPECSKRFMRSDHLAKHIKTHQNKK-------------------------------------VIHSSSTVLASVEAGRDDALITAGGTTLILANIQQGSVSGIGTVNTSATSNQDILTNTEIPLQLVTVSGNETME------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q02447-1", "uniprot_id": "SP3_HUMAN", "id": "Q02447-1", "name": "Transcription factor Sp3", "aln": "------------------------------------------------MTAPEKPVKQEEMAALDVDSG---GGGGGGGGHGEYLQQQ-------------------QQHG--NGAVAAAAAAQDTQPSPLALLAATCSKIGPPS----------PGDDEEEA--AAAAG-------APAAAG-ATGDLASAQLGGAPNRWEVLSATPTTIKDEAGNLVQIPSAATSSGQYVLPLQNLQNQ-QIFSVAPGSD-----SSNGTVSSVQYQVIPQIQSADGQQVQIGFTGSSDNGGINQESSQIQIIPGSNQTLLASGTPSANIQNLIPQT-------GQVQ-VQGVAIGGSSFPG----QTQVVANVPLGLPGNITFVPIN---SVDLDSLGLSGSSQTMTAGINADGHLINTGQAMDSSDNSERTGERVSPDINETNTDTDLFVPTSSSSQ---LPVTIDSTGILQQNTNSLTTSSGQVHSSDLQGNYIQSPVSEETQAQNIQVSTAQPVVQHLQLQESQQPTSQAQIVQGITPQTIHGVQASGQNISQQALQNLQLQLNPGTFLIQAQTVTPSGQVTWQTFQVQGVQNLQNLQIQNT---AAQQITLTPVQTLTLGQVAAGGAFTSTPVSLSTGQLPNLQTVTVNSIDSAGIQLHPGENADSPADIRIKEEEPDPEEWQLSGDSTLNTNDLTHLRVQVVDEEGDQQHQEG----------KRLRRVACTCPNCKEGGGRGTNLGKKKQHICHIPGCGKVYGKTSHLRAHLRWHSGERPFVCNWMYCGKRFTRSDELQRHRRTHTGEKKFVCPECSKRFMRSDHLAKHIKTHQNKK-------------------------------------GIHSSSTVLASVEAARDDTLITAGGTTLILANIQQGSVSGIGTVNTSATSNQDILTNTEIPLQLVTVSGNETME------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BD33-1", "uniprot_id": "A0A8M2BD33_DANRE", "id": "A0A8M2BD33-1", "name": "", "aln": "-------MPPRITRRCAVPSCGKTQSLHGLPSDPNLRKQWVNFIF---NEVPDRIIKSLFVCSLHFTTDSFTNKTQFDAGFSERLKVKDDAVPTILDPKVMQPQRSSHKTSREMGCQTEELNTQDGQCQTFPDLKPHTLKLEPRSET-----PEQPAKQQEMAALDVDSSQSDFLQPASGAQDQQTTDLTAIQMTGSSDRWEVLTPVSSVKGEPAVVHVPSGGLLGSNGQYVVPLQTMAGQTQPVFVTAGVD-----GTG--ANGVQYQVIPQLQGADG--ASLSYTASAADG--STLGTDIAILPDGTQG-IATATNANDLQGLLSQS-------GHVQQIPTVSLAGSGFGT----QGQVVAN--MGLPGNITLVPINSLSNVDLESLGLAG-AQTIATSVTADGQLIMTGPTTTTSDNQGESGK-CTESLNANDANANAFVPTTTSSTSTSLPETIDGTGVLTQAT---AVSAGHQDLSYIQQN---------------------------------HTTGGEQVVQLLPAQTADG--------AAQTLQSVQL-LNAGTFLIQAQTVSPTGQIQWQTFQVQGVQNLQNLQLPAAGGVSSPQITLAPVQTLSLGQSGTTGAL---------GQIPNLQTVTVNSVG----QYQQDENTESHTDIQIKEE-PESDDWPN---STLSTSDLAHLRVRLVEEDMEGTGQEG----------KRLRRVACTCPNCKEAGGRGSSMGKKKQHICHIPGCGKVYGKTSHLRAHLRWHSGERPFICSWSYCGKRFTRSDELQRHRRTHTGEKKFVCPECSKRFMRSDHLAKHIKTHQNKK-------------------------------------GLNSNTGVGQTEAAAPSDTIITGGGATVILANLQQAGT-------------QDLLSNSDLPLQLVTVSASEVLE------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KHC8-1", "uniprot_id": "A0A0B4KHC8_DROME", "id": "A0A0B4KHC8-1", "name": "", "aln": "MLQYKSAASAATSAPPATPLAAGGSSKATIPPNGASAAASQTQVHGAPGTPTMQQIINIHQMPPQFAGGAVAGNGQNAGMPQNMFQIVQPMPMQTVNIDGQEAIFIPNLNAQLATAQAVNFNGQQAFITPNGQILRAPQMAANPAASNCIQLQQLNGLGQEQTQLITIPGTNIQIPVTNLIQQQQQAQQVHQGTVQQQAQGTNASGANGSGVTNSGTAGQLPGSITIPGTNLQIPTSVAAANGLLGNISNISNLLGGGQSIKLENGQLQMRPQLVQFPAPAMPQQQQTVAVQIPVQTANG-QTIYQTVHVPVQAAATSSGGLQNLMQAQSLQMPSASQMQIIPQFSQIAQIVTPNGQIQQVQLAMPYPQLPPNANIIHIQNPHQQQQQQVQQQQQQQQAQQQQQAQQQQAQQQQQQQVQAQHQQLLQAISDASAGGQLPPNQPITITNAQG---QQLTVIPAQLRPNAPTAPTPAPAGVPTPMQMPNLQALPIQNIPGLGQVQIIHANQLPPNLPANFQQVLTQLPMSHPQVQTQGQVQVMPKQEPQSPTQMITSIKQEPPDTFGPISATGNPPAPASTPNTASPQQQQIKFLHTESNS--LSSLSIPASIQITALPQQATNTPNTPATTQPIPVSLPARSKVNAVTTSSTQITIAPTGGQVVSVTTQARGATASIR-STNTSTTTITTPSQSHLNMNISVASVGGAATGGGGGTATGEPKPRLKRVACTCPNCTDGEKHSD---KKRQHICHITGCHKVYGKTSHLRAHLRWHTGERPFVCSWAFCGKRFTRSDELQRHRRTHTGEKRFQCQECNKKFMRSDHLSKHIKTHFKSRSGVELIELSIKQETKGGNAPKSISTVNGIVTIEIPGGGSAAAGSGASSVAATVAGSTVTPGGATIVQLPTVEASGGGDSFGDDEDDEEDDELTEEDDEDEELDEDDMDDCEDEEDDEDPELDSGDEVKMTIAVSEPGDNSSNXHSESLFMEQFLFDHFP", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : . . .. . : :: : : *: . : : . :* : . .. . : . : : . : . * : .: . .. . . . .. * *: **: . : : . . * *:.* . .:*.*: .::* : .: .. . * :* ** * .:: *: . : :.: * *: : . : . : : : .: :. :.:. *: : : : . : :.. . * * : .* : : . ..** : * .*.. . *::: *: : :.:* :* * .: . .:* ..*.. : . . . : : .. :*:.* . :**.:.: . * **:*********.:. :. **:******.** ****************:*****:*.* :**********************:* * **.*:*******:****** :.: : : * .: :* **:*:: :.. :* *:: : : : . : * ", "identical_positions": 133, "similar_positions": 187, "identity": "13.37%" }, { "cls_id": "homologset.agr.MGI:1277167", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K4I3-1", "uniprot_id": "A0A0G2K4I3_RAT", "id": "A0A0G2K4I3-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTQWDLKTVLSLPQYPGEFLHP-----------VVYACTAVMLLCLLASVITYILHQSAIRISRKGRHALLNFCFHAALTFTVFAGGINRTKHPILCQAVGIALHYSTLSTMLWIGVTARNIYKQVTKKALPCPG-----ADQP--PYPKQPLLRFYLISGGVPFIICGVTAATNIRNYGTEDEDVAYCWMAWEPSLGAFYGPAAFITLVTCVYFLCTYVQLRRHPERRYELRERTEEQQRLAVPETGHRHGMRP-----GTPPTCDALAASQLQN---------------------------EHSFKAQLRAAAFTLFLFTATWTFGALAVSQGDFLDMIFSCLYGAFCVTLGLFVLIHHCAKREDVWQCWWS-----CCPSRGDTSAT---KPSAHPTLDANGDALGH----TACLQDSPCPGKLRGFGHPPASHCKMTNLHAAQGHVSCLS----------------------------------------------PATPCCAKMHCEQ-LMEEEA-HVHMGEEDAFPHDHH----------------------------LHDPHLHRCLKGRTKPHYFSRHQAAAAEREYAYHIPS-SLDGSPHSSRTESPTSS--------------------------------------------------------------------------------------------LEGPMGVHTLACCAQADPF---------PMVS--QPEGGDTSPGLYG----------------------------------------------------------------------------------CPPR----LSPGPAHLEMLR-RTQSLPFGSP---SQNGLL--QGDVREGLPFGTDGTGNIRTGPWKNETTV-----------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C4G9-1", "uniprot_id": "AGRA1_MOUSE", "id": "Q8C4G9-1", "name": "Adhesion G protein-coupled receptor A1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTQWDLKTVLSLPQYPGEFLHP-----------VVYACTAVMLLCLLASVITYILHQSAIRISRKGRHALLNFCFHAALTFTVFAGGINRTQHPILCQAVGIALHYSTLSTMLWIGVTARNIYKQVTKKALPCPG-----ADQP--PYPKQPLLRFYLISGGVPFIICGVTAATNIRNYGTEDEDVAYCWMAWEPSLGAFYGPAAFIALVTCVYFLCTYVQLRRHPERRYELRERTEEQQRLAVPESGHRHGVRP-----GTPPTCDALAASQLQN---------------------------EHSFKAQLRAAAFTLFLFTATWTFGALAVSQGHFLDMIFSCLYGAFCVTLGLFVLIHHCAKREDVWQCWWS-----CCPSRGDTSTT---KPGAHPTLDANGDALGH----TACLQDSPCPGKLRGFGHPPASHCKMTNLQAAQGHVSCLS----------------------------------------------PATPCCAKMHCEQ-LMEEEAAHIHMAEEDVYPHDPH----------------------------LHDPHLHRCLKGRTKSHYFSRHQAAAAEREYAYHIPS-SLDGSPHSSRSESPTSS--------------------------------------------------------------------------------------------LEGPMGMHTLACCAQADPF---------PMVS--QPEGGDTSPGLYG----------------------------------------------------------------------------------CPPH----LSPGPAHLEMLR-RTQSLPFGGP---SQNGLL--QGDVREGLPFGTDGTGNIRTGPWKNETTV-----------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86SQ6-3", "uniprot_id": "AGRA1_HUMAN", "id": "Q86SQ6-3", "name": "Adhesion G protein-coupled receptor A1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDLKTVLSLPRYPGEFLHP-----------VVYACTAVMLLCLLASFVTYIVHQSAIRISRKGRHTLLNFCFHAALTFTVFAGGINRTKYPILCQAVGIVLHYSTLSTMLWIGVTARNIYKQVTKKAPLCLD-----TDQP--PYPRQPLLRFYLVSGGVPFIICGVTAATNIRNYGTEDEDTAYCWMAWEPSLGAFYGPAAIITLVTCVYFLGTYVQLRRHPGRRYELRTQPEEQRRLATPEGGR--GIRP-----GTPPAHDAPGASVLQN---------------------------EHSFQAQLRAAAFTLFLFTATWAFGALAVSQGHFLDMVFSCLYGAFCVTLGLFVLIHHCAKREDVWQCWWA-----CCPPRKD----------AHPALDANGAALGR----AACLH-SPGLGQPRGFAHPPG-PCKMTNLQAAQGHASCLS----------------------------------------------PATPCCAKMHCEP-LTADEA-HVHLQEEGAFG---------------------------------HDPHLHGCLQGRTKPPYFSRHPAE--EPEYAYHIPS-SLDGSPRSSRTDSPPSS--------------------------------------------------------------------------------------------LDGPAGTHTLACCTQGDPF---------PMVT--QPEGSDGSPALYS----------------------------------------------------------------------------------CPTQPGREAALGPGHLEMLR-RTQSLPFGGP---SQNGLP--KGKLLEGLPFGTDGTGNIRTGPWKNETTV-----------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58GY35-1", "uniprot_id": "A0AC58GY35_DANRE", "id": "A0AC58GY35-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRRKHRLEHKEPDLKRVLSFPPYPGDYLHP-----------VVYACTAVMLLCLLISIMTYIVHHSIIRISRKGWHMLLNFLFHTAMTFGVFAGGINQIKYPVICQVVGIILHYSSLSSMLWLLFTARNVCKEVSKAPPIPQD-----RDPPTQPRPKATIFRFYLVSGGVPLIIVGVTAAVNLDNYGSRD-DAPYCWMAWEPSLGGFYGPTAFLVLVMCIYFLCTYVQLKRHPERKYELKAMTEEQQRLAVAEIGHCHAVSGEPGEHGDHTGCTAITASMLAN---------------------------EHSFKAQLRATAFTLFLFLATWVFGALAVSQGHFLDMIFSCLYGAFSVTLGLFLLIQHCAKRDDVWHRWWA-----CCPNKPKVEVNGEAAGNAIPTTQSHSHTPSHGQNQIHCQVDSSCLGKPLLSPHLSP-HCKLGSLPSTQNHTS----------------------------------------------------TCCATLHSPSSLIGSSTRPQSLPDELPRP----------------------------------TLPLQSCLKDRSKTRSFNRPRPC--LRDYSYHMTSTSMDGSVHSSHLDSPHSVH-------------------------------------LDNPLTCHTSHLDTQLSCHSPHPDNQLRCPSPSPHLETLASHGLHDSLSCHSAHLDSQLSCHRHMCCAKADPFSSICCPNADPFVSPCQAEDPDMGSLMYS----------------------------------------------------------------------------------CAKMADK-EDESMLHLDITPPRVSHATLGRKGTLSRRGTLSRNSSQHEDYAITSDSTGNIRTGPWKNETTV-----------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7KV24-1", "uniprot_id": "Q7KV24_DROME", "id": "Q7KV24-1", "name": "", "aln": "MPTATATSTAAEGGQAVQVQTHQDTELPQNPETGIATGQGTASSCPRKCSCRSTAENIHSLKIRCDEQQITNWRELDFGEDVTSIVSINASKNSIALITAEDFRNFTELKRLDLSFNLLTELDKDTFGDSLAHLEKLKLAGNAISHIYEGTFDQMPKLKLLDLSGNPLACDCGLIWLIAWSSSREVRLQPPPKCESPGNFRGMPLKKLRVGKDFHCETLLQPLLELIPSQNQVAFEGDELQLKCHAPRVAIGVPRESEDLPTKAYVFWGWSEKIRAKNSTEDIIYQDPTKVFGDVNLETRHSTDSGILQSILRIASLTQNHTGMWDCTLRSQQANLSQAIVLHVVAKGTLYCEARVVHTNKGTYHWPRTMRGETVLQECVEEPSDATQARRASHECGPSGEWLNLDTESCVYVSETTRILEQFAKVNLTLTKGQNALEIARRLHNFTQAQTQLNRIRDPMDLEYIARTLVKYLDQLEQPQQQQEISHLLMDIVSQLLNLPAHLFRAAQSEQGTGQRLLHVVESSAMRLALASTQAEPLPAEMIPWRGSLAQQRNLFVEFFNISLDAFVSLSCVWLEQSPRGFQCNSANDTIPMYEHGDIDAAIQLPYSVIGNSSTTLPATTTIRSLRLMISLHRNGKLLPNLRGSHNESLSSAIIGILAYSSDGEALQFRADNELDPEEDVYQQRVTVMLRAHPYHNPLSAPQPAWWDADEQRWETSVCQQHYQHRTLVMFSCSRTGYYGLLQRSQYLNDFRSEESGARFRHPPAAVYAGCGLLFACCAFNAVTFAVFGRAVRINRVQRHALVNTWLALGALALAFSLGIYQTASQPQCRLLGLLMHYLGLCVLLWVCVSLSSMYKRLTKTTTSGQGQCPGQDMEPQRERERKPILGIYLVGWGIALLICGISSAVNLAEYATYD----YCFLHSSTTLNALLVPAVILVIFCGILALCIYYQLSQQAVNVLQLQMQHQQNRQYSDNNTQATEHIDLDWLDANGSATTAAIGGGSGNHGGRKEQDHMQEQYSTLSNPLSSIVDDFERSNLSHLRGHFIFLVLYAGAWLSAAAYVNGG---QELYVLSFAGCCSVLGIFLLIFYNLSRNDARQAWSQGRDGRSIPAKLVTYNNGSQARGAHPSSMMPGPGTAMISNSIVAYKANPGPGSLYEANNSAGSRSNSQCSRSMRSQTRSQTRSQQEQLLQANGAGGVTIINNTSGQPGAGGGPAAGGVSGSTGGAPVPPHSLNALLHGSSHDLIPSAEIFYNPNQINVARKFFKKQKRLAKRNNFELQRQTMPQMQLQMQMQMQLHSQHSLSDASSEQLYSRHHNAMTMLAGGSKINNTNLHYKNQGSPMAGAPKEHGNMGAMSSGGDSMQFKRFVPASASSASKIMQANIYTNIPETLTPQHEVIKLRANGRTRTPSLLDETLHELDDDEEDEEEEEHGQTPATMEEPEHELEEEDASSLDEHAPLYANTLPPASGMSSLFRNRGSSHQPMSSTPVKQPSLEAMNSLGLPEVSLEEPLLQKHEIYVSNSLQVTTSNSIQLDDDFPSVLIRFSQQQQSKSLNNISEMLAGGGGGGGNAPGLDSLGDQQESSQLSVNEGSTLEEQQLRQIYSCSSSNLSQLKGHHPTATVDTEDDGRLLSGSPTNESDLNYQNSEISIRSHGLYAPQADNDLNLTLTDDFRCYQSSNASDADVDVLNEFDDEFVAATGGERVVGDAEQDPHHDHDQDTSIDELYEAIKCRSPLRNKQEAVERFERERERDREKEMEMEAKPLSNSHNENLNETIEDDSSQSSVISYIDPRAANEPRPFPS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :*. . * .:: .*** .::: * . :*: :. :**.* * *:* : . .*: ** : *: :*: :** *. :**: .: .: *.::* . . * : .:: :**:. *:.::* *:::*.*: :*.: * **:: ..:*..: *:.::.:. : * * ** ::. . :*: ::::: : : : . . * .. : *:* ::**. : *.*: .:* .* *. * : :: :.. . .**:*:** : .*:*. : * . * : * *: . . . .. *. : . .: : :.:. . * :* .: :: : .*.. :. :.* . :: . .:. . :.* .. . : . . : *: : : : .. . . .. :*.: . . . .. ::. *.: :*. .**: : ", "identical_positions": 78, "similar_positions": 198, "identity": "4.32%" }, { "cls_id": "homologset.agr.MGI:1277169", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AYG5-1", "uniprot_id": "ECHD1_RAT", "id": "Q6AYG5-1", "name": "Ethylmalonyl-CoA decarboxylase", "aln": "-----------------------MAKSLL-ASSLSVRTKIL-QTGVSLYNTTHGFHEEEVKKILEQFPGGSIDLQKKQ-NGIGILTLNNS-NKMNAFSGAMMLQLLERVIELENWTEGKGLIVHGAKNTFCSGSDLNAVKALSTPENGVALSMFMQNTLTRFMRLPLISVALVQGWAMGGGAELTTACDFRLMTEESVIRFVHKEMGIVPSWGGASRLVEIIGSRQALKVLSGTFKLDSKEALRIGLADEVLQ-PSDEATALEQAQEWLEQFVSGPAQVIRGLKKSVCSGRELYLEEALQNERDVLETLWGGPANLEAIAKKGKHTK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D9V3-1", "uniprot_id": "ECHD1_MOUSE", "id": "Q9D9V3-1", "name": "Ethylmalonyl-CoA decarboxylase", "aln": "MRRCEVNSKPISEYFGIPCENREMAKCLL-TSSLSVRTKLL-QTGVSLYNTSHGFHEEEVKKILEQFPGGSIDLLKKQ-NGIGILTLNNP-NKMNAFSGVMMLQLLERVIELENWTEGKGLIIHGAKNTFCSGSDLNAVKALSTPESGVALSMFMQNTLTRFMRLPLISVALVQGWAMGGGAELTTACDFRLMTEESVIRFVHKEMGIVPSWGGTSRLVEIIGSRQALKVLSGTLKLDSKEALNIGLTDEVLQ-PSDETTALEQAQEWLEKFVSGPPQVIRGLKKSVCSARELYIEEALQNERDVLETLWGGPANLEAIAKKGKHTK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NTX5-1", "uniprot_id": "ECHD1_HUMAN", "id": "Q9NTX5-1", "name": "Ethylmalonyl-CoA decarboxylase", "aln": "-----------------MALKQEMAKSLLKTASLSGRTKLLHQTGLSLYSTSHGFYEEEVKKTLQQFPGGSIDLQKED-NGIGILTLNNP-SRMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAVKSLGTPEDGMAVCMFMQNTLTRFMRLPLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVLSGALKLDSKNALNIGMVEEVLQ-SSDETKSLEEAQEWLKQFIQGPPEVIRALKKSVCSGRELYLEEALQNERDLLGTVWGGPANLEAIAKKGKFNK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1R6N4-1", "uniprot_id": "ECHD1_DANRE", "id": "F1R6N4-1", "name": "Ethylmalonyl-CoA decarboxylase", "aln": "------------------MSMWGAVRCRLIQTRSAVR-KILQQNRAFCSGSSVG-----IREKLLAFPGGSVELQKLQESGIAVLTVSNPPARMNAFSGCMMLELEQRVNELEIWTEGKAVIVQGAAGNFCSGSDLNAVRAIANPHDGMKMCEFMQNTLARLLRLPLISVALVEGRALGGGAELTTACDFRLMTSDAVIQFVHKHMGLVPGWGGAARLVGIIGSRNALKLLSGARKVDPDYGKQMGLVDEVLQCSSGEGKALAHAEHWIAPFIKGPAPVIQAIKKVVVSGRELSLDEALKCERSVFGTVWGGPANLEALASKPKHK-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:. * : : * *:* *. .:: * ::: * *****::* * : .**.:**:.*. :****** ***:* ::* *** *****.:*::** ..*.********:::..*..*: :. ******:*::**********:* *:*****:********** :: *:****.**::*.***::*** *****:***:***: *:*.. . .:*:.:**** .*.* .:* .*:.*: *:.**. **:.:** * *.*** ::***: **.:: *:*********:*.* *.. ", "identical_positions": 153, "similar_positions": 96, "identity": "46.79%" }, { "cls_id": "homologset.agr.MGI:1277171", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ESI7-1", "uniprot_id": "DCX_RAT", "id": "Q9ESI7-1", "name": "Neuronal migration protein doublecortin", "aln": "-------------------------------------------------------------------MELDFGHFDERDKASRNMRGSRMN--------------------------------------GLPSPTHSAHCSFYRTRTLQALSNEKKAKKVRFYRNGDRYFKGIVYAVSSDRFRSFDALLADLTRSLSDNINLLQGVRYIYTIDGSRKIGSMDELEEGESYVCSSDN-FFKKVEYTKNVNPNWSVNVKTSANMKAPQSLASSNS----------------------------AQARENKDFVRPKLVTIIRSGVKPRKAVRVLLNKKTAHSFEQVLTDITEAIKLETGVVKKLYTLDGKQVTCLHDFFGDDDVFIACGPEKFRYAQDDFSLDENE-------CRVMKGNPSATAGPKASPTPQKTSAKS----PGPMRRSKSPADSGNDQDANGTSSSQLSTP-------------------------------------------KSKQSPISTPTSPGSLRKHK-DLYLPLSLDDSD----------------------------------SLGDSM------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88809-1", "uniprot_id": "DCX_MOUSE", "id": "O88809-1", "name": "Neuronal migration protein doublecortin", "aln": "-------------------------------------------------------------------MELDFGHFDERDKASRNMRGSRMN--------------------------------------GLPSPTHSAHCSFYRTRTLQALSNEKKAKKVRFYRNGDRYFKGIVYAVSSDRFRSFDALLADLTRSLSDNINLPQGVRYIYTIDGSRKIGSMDELEEGESYVCSSDN-FFKKVEYTKNVNPNWSVNVKTSANMKAPQSLASSNS----------------------------AQARENKDFVRPKLVTIIRSGVKPRKAVRVLLNKKTAHSFEQVLTDITEAIKLETGVVKKLYTLDGKQVTCLHDFFGDDDVFIACGPEKFRYAQDDFSLDENE-------CRVMKGNPSAAAGPKASPTPQKTSAKS----PGPMRRSKSPADSGNDQDANGTSSSQLSTP-------------------------------------------KSKQSPISTPTSPGSLRKHKVDLYLPLSLDDSD----------------------------------SLGDSM------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43602-1", "uniprot_id": "DCX_HUMAN", "id": "O43602-1", "name": "Neuronal migration protein doublecortin", "aln": "-------------------------------------------------------------------MELDFGHFDERDKTSRNMRGSRMN--------------------------------------GLPSPTHSAHCSFYRTRTLQALSNEKKAKKVRFYRNGDRYFKGIVYAVSSDRFRSFDALLADLTRSLSDNINLPQGVRYIYTIDGSRKIGSMDELEEGESYVCSSDN-FFKKVEYTKNVNPNWSVNVKTSANMKAPQSLASSNS----------------------------AQARENKDFVRPKLVTIIRSGVKPRKAVRVLLNKKTAHSFEQVLTDITEAIKLETGVVKKLYTLDGKQVTCLHDFFGDDDVFIACGPEKFRYAQDDFSLDENE-------CRVMKGNPSATAGPKASPTPQKTSAKS----PGPMRRSKSPADSGNDQDANGTSSSQLSTP-------------------------------------------KSKQSPISTPTSPGSLRKHK-DLYLPLSLDDSD----------------------------------SLGDSM------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7PLI7-1", "uniprot_id": "DCLK_DROME", "id": "Q7PLI7-1", "name": "Serine/threonine-protein kinase CG17528", "aln": "MELEKVKINSLHCNDAVLSSLQASPSATSPQSVPSKANVVTEASIIEKTNQPHNVQEDNNYNRDCDSPESSSSEQDKELDDLRNLHSSSLTNSVVVGKSTGSLNGVYSITSVTSETKTLESVVTTNSASGSACLSNTPTADHIKKRIPSSRTPTRKALRIKFYRNGDRFYPGITIPVSNERYRSFERLFEDLTRLLEENVKIPGAVRTIYNLCG-KKITSLDELEDGQSYVCSCNNENFKKVEYNTGSQPLSNLPLSNSRSNSHRLAKCRPSSPLKNGLLAGSSPFPACGGGTGNGSPLIASRLSDRVTVVHPRIVTLIRSGTKPRRIMRLLLNKRNSPSFDHVLTAITQVVRLDTGYVRKVFTLSGIPVVRLSDFFGSDDVFFAYGTERIN-TAEDFKLEAEEQRAINVIRKTMRTTGTTCKGPKPKMPIKSKKVYPPLVDSEPFKAETTPEDDRHAALLTSTGMEINELPSNIRNTYSLGRIIGDGNFAIVFKIKHRQTGHSYALKIIDKNKCKGKEHYIDAEVRVMKKLNHPHIISLILSVDQNTNMYLVLEYVSGGDLFDAITQVTRFSENQSRIMIRHLGAAMTYLHSMGIVHRDIKPENLLVKLDEHGNVLELKLADFGLACEVNDLLYAVCGTPTYVAPEILLEVGYGLKIDVWAAGIILYILLCGFPPFVAPDNQQEPLFDAIISGIYEFPDPYWSDIGDGVRDLIANMLQADPDVRFTSEDILDHSWTIGNKGNECTTYKR", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . .. *:. . **::.* :. * .. :::. ... :.* .: : :** :::*******:: **. .**.:*:***: *: **** *.:*::: .** **.: * :** *:****:*:*****.:* ******... :* .: :..* . . : . ..* :: :. .*:*::**:****.***: :*:****:.: **::*** **:.::*:** *:*::**.* *. * ****.****:* *.*::. : :**.*: :* :.*: . :: ***.. . :.... . . *:: ..:* *. : ..*. . . * *.*: *.: . . :* : * **:*:. ** :* ", "identical_positions": 127, "similar_positions": 146, "identity": "16.93%" }, { "cls_id": "homologset.agr.MGI:1277172", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K0E0-1", "uniprot_id": "A0A0G2K0E0_RAT", "id": "A0A0G2K0E0-1", "name": "Probable ATP-dependent RNA helicase DDX56", "aln": "--MEDQ--------EALGFEHMGLDPRLLQAVTDLGWSRPTLIQEKAIPLALEGK-DLLARARTGSGKTAAYAIPMLQLLLHKKATGPVMEQA-VRGLVLVPTKELARQAQSMIQQLASYCARDVRVANVS-AAEDSASQRAVLMEKPDVVVGTPSRILNHLQQKN-LKLRDSLELLVVDEADLLFSFGFEDELKSLLCHLP--RIYQAFLMSATFNEDVQTLKELVLHNPVTLKLQESQLPGPDQLQQFQVVCETEEDKFLLLYALLKLSLIRGKALLFVNTLERGYRLRLFLEQFSIPSCVLNGELPLRSRCHIISQFNQGLYDCVIATD-----------------------AEILGPQVKAKRQGRGSKGDKASDPESGVARGIDFHHVSAVLNFDLPPTAEAYVHRAGRTARANNPGIVLTFVLPTEQS--------SLGKIEELLSG----EGQAP--ILLPYQFQMEEIESFRYRCRDAMRSVTKQAIREARLKEIKEELLHSEKLKTYFEDNPRDLQLLRHDLPLHPAVVKPHLGNVPDYLVPAALRGLVHPR-------KKRRKMPFS-RKAKKVKTQNPLRDFKHRGKKPKPTAKPS----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D0R4-1", "uniprot_id": "DDX56_MOUSE", "id": "Q9D0R4-1", "name": "Probable ATP-dependent RNA helicase DDX56", "aln": "--MEDQ--------EALGFEHMGLDPRLLQAVTDLGWSRPTLIQEKAIPLALEGK-DLLARARTGSGKTAAYAIPMLQSLLHKKATGPVMEQA-VRGLVLVPTKELARQAQAMIQQLAAYCARDVRVANVS-AAEDSASQRAVLMEKPDVVVGTPSRVLSHLQQNT-LKLRDSLELLVVDEADLLFSFGFEDELKSLLCHLP--RIYQAFLMSATFNEDVQTLKELVLHNPVTLKLQESQLPGPDQLQQFQVVCETEEDKFLLLYALLKLSLIRGKALLFVNTLERGYRLRLFLEQFSIPSCVLNGELPLRSRCHIISQFNQGLYDCVIATD-----------------------AEILGPQVKGKRRGRGSKGNKASDPESGVARGIDFHHVSAVLNFDLPPTAEAYVHRAGRTARANNPGIVLTFVLPAEQP--------FLGKIEDLLSG----EGEAP--ILLPYQFQMEEIESFRYRCRDAMRSVTKQAIREARLKEIKEELLHSEKLKTYFEDNPRDLQLLRHDLPLHPAVVKPHLGHVPDYLVPAALRGLVHPR-------KKRRKVPFS-RKAKKVKAQNPLRDFKHRGKKPKPAAKPS----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NY93-1", "uniprot_id": "DDX56_HUMAN", "id": "Q9NY93-1", "name": "Probable ATP-dependent RNA helicase DDX56", "aln": "--MEDS--------EALGFEHMGLDPRLLQAVTDLGWSRPTLIQEKAIPLALEGK-DLLARARTGSGKTAAYAIPMLQLLLHRKATGPVVEQA-VRGLVLVPTKELARQAQSMIQQLATYCARDVRVANVS-AAEDSVSQRAVLMEKPDVVVGTPSRILSHLQQDS-LKLRDSLELLVVDEADLLFSFGFEEELKSLLCHLP--RIYQAFLMSATFNEDVQALKELILHNPVTLKLQESQLPGPDQLQQFQVVCETEEDKFLLLYALLKLSLIRGKSLLFVNTLERSYRLRLFLEQFSIPTCVLNGELPLRSRCHIISQFNQGFYDCVIATD-----------------------AEVLGAPVKGKRRGRGPKGDKASDPEAGVARGIDFHHVSAVLNFDLPPTPEAYIHRAGRTARANNPGIVLTFVLPTEQF--------HLGKIEELLSG----ENRGP--ILLPYQFRMEEIEGFRYRCRDAMRSVTKQAIREARLKEIKEELLHSEKLKTYFEDNPRDLQLLRHDLPLHPAVVKPHLGHVPDYLVPPALRGLVRPH-------KKRKKLSSSCRKAKRAKSQNPLRSFKHKGKKFRPTAKPS----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VRI0-1", "uniprot_id": "Q9VRI0_DROME", "id": "Q9VRI0-1", "name": "Probable ATP-dependent RNA helicase DDX56", "aln": "MSQMTQ--------KTVQFHELELDQRILKAVAQLGWQQPTLIQSTAIPLLLEGK-DVVVRARTGSGKTATYALPLIQKILNSKLN--ASEQY-VSAVVLAPTKELCRQSRKVIEQLVESCGKVVRVADIADSSNDTVTQRHALSESPDIVVATPANLLAYAEAGS-VVDLKHVETLVVDEADLVFAYGYEKDFKRLIKHLP--PIYQAVLVSATLTDDVVRMKGLCLNNPVTLKLEEPELVPQDQLSHQRILAE-ENDKPAILYALLKLRLIRGKSIIFVNSIDRCYKVRLFLEQFGIRACVLNSELPANIRIHTISQFNKGTYDIIIASD-----------------------EHHMEKP--GGKSATNRKSPRSGDMESSASRGIDFQCVNNVINFDFPRDVTSYIHRAGRTARGNNKGSVLSFVSMKESK--------VNDSVEKKLCDSFAAQEGEQ--IIKNYQFKMEEVESFRYRAQDCWRAATRVAVHDTRIREIKIEILNCEKLKAFFEENKRDLQALRHDKPLRAIKVQSHLSDMPEYIVPKALKRVVGTSSSPVGASEAKQPRQSAAKAAFERQVNDPLMASQVDFGKRRPAHRRKKKAL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06218-1", "uniprot_id": "DBP9_YEAST", "id": "Q06218-1", "name": "ATP-dependent RNA helicase DBP9", "aln": "MSYEKKSVEGAYIDDSTTFEAFHLDSRLLQAIKNIGFQYPTLIQSHAIPLALQQKRDIIAKAATGSGKTLAYLIPVIETILEYKKTIDNGEENGTLGIILVPTRELAQQVYNVLEKLVLYCSKDIRTLNISSDMSDSVLS-TLLMDQPEIIVGTPGKLLDLLQTKINSISLNELKFLVVDEVDLVLTFGYQDDLNKIGEYLPLKKNLQTFLMSATLNDDIQALKQKFCRSPAILKFNDEEINKNQNKLLQYYVKVSEFDKFLLCYVIFKLNLIKGKTLIFVNNIDRGYRLKLVMEQFGIKSCILNSELPVNSRQHIVDQFNKNVYQLLIATDDTEYIKEEDDEIEEGHNTENQEEKSLEGEPENDKKPSKKKKVQVKKDKEYGVSRGVDFKNVACVLNFDLPTTAKSYVHRVGRTARGGKTGTAISFVVPLKEFGKHKPSMLQTAKKDERILSRIIKQQSKLGLELQPYKFDQKQVEAFRYRMEDGFRAVTQVAIREARVKELKQELLASEKLKRHFEENPKELQSLRHDKELHPARVQQHLKRVPDYLLPESARG------------NGTKVKFVPFHNAKKRHSHKKGRVSKPKNGKVDPLKNFK----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .: *. : ** *:*:*: ::*:. *****. **** *: * *::.:* ****** :* :*::: :*. * . *: . .::*.**:**.:* ::::*. *.: :*. ::: .*:. . * :.*:::*.**..:* : . :: *****.**::::*::.::: : :** *:.*:***:.:*: :* ..*. **::: :: :: : * ** : *.::** **:**:::***.::* *:::*.:***.* :*:**.*** . * * :.***:. *: :**:* : . * * * ..:**:**: * *:***:* :*:**.*****..: * .::** :. . :. : . : : *:* :::*.**** .* *:.*: *::::*::*:* *:* .**** .**:* ::** **** *:. *: ** :*:*::* : : : : . : * . : :. : * * . . ", "identical_positions": 165, "similar_positions": 193, "identity": "27.0%" }, { "cls_id": "homologset.agr.MGI:1277173", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8M3AYL2-1", "uniprot_id": "A0A8M3AYL2_DANRE", "id": "A0A8M3AYL2-1", "name": "Rho guanine nucleotide exchange factor 25", "aln": "--MKSLPK-NQGRTDEILGAMADMLTSLAIPNQKWNSDSIEHLSVKQERKTSQRPPWDTEGLNWEDMSRDSLERVRRRDRANSYS-------AAGSEGSISTSVASLPPQASG-----SSAPNSPGSRRSVSTLKKWLTNPVRKLSAGAAGSAKGERQVRRLEGKPPPPPTRSSQELGSPQSTEEQFTILPGIDKELEWKDGLPALGDCDPGLLQSYSFQSDSPQGSTTLG-QTQISQCTSQQADDNGSVLMDDNSSQSSACADTEEDRKSALEKSMYVLNELIETEKLYVADLGLIVEGYMATMNVKGIPEDMKGK--DKIVFGNIHQIYDWHKDYFLAELEKCVAEPERLAQLFIKHERRLHMYVVYCQNK-PKSEHIVSEYIETYFEELKQQLGHRLQLNDLLIKPVQRIMKYQLLLKDFHKYYTKAGMDTEELEKAVEVMCFVPKRCNDMMNVGRLQGFEGKITAQGKLLQQDTFTITEQDSS--ILSRAKERRVFLFEQLVIFSEPIDRK-KGFSLPGYIFKNSIKISCLGVEACVDGDPNRFALTSRGADGSTVRYVLYSSSPDICMAWVSDVSQILETQRNFLNALQSPIEYQRRESKSNSLGRSIKPPLSAVAGLRP--HSSASIDRHKLPCLRSCNTSLPSLYLPSQVPTDDHSQPESTPVDSRLNSQTVSPTHVQLAFSEEPSFSQAPLNCQAVSNGLYSSSTQGSQISGEGGRRVSQRECRMSVPSPSSTLQRSSNLAQLDEDDL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E7FF78-1", "uniprot_id": "E7FF78_DANRE", "id": "E7FF78-1", "name": "", "aln": "--MKSLAK-LQGNTEQLLMSLSNTLPSLTLNNQQWIQEQNEGCLLLEEKQGCSKKGAGPE--NEKQSWNQRLEHIPEDKDSYTLTGLSDVSLPPDDPPSASVSTDDLSPISPSNHQLFSSRRASVTSTRSIKAFKRWLSSPVRRLSLGGGNKSQSSKGIQSPEG-----STYMFLPLSPAQS------PLSPMEKSQKLTRSYRSL-DCG---ELSRETSPDSPYYPRYLNDLFQRNQSFDVQTSVSPSLTDKTLVEQSQSLEDNEQHRRTALEKSIYVLTELVETEKLYVEDLGLVVEGYMLTMRSFGVPEYLEGK--DKIVFGNIHQIYDWHKDYFLGELEKCVSEPDLLAQLFIKHERRLNMYVVYCQNM-PKSEHIVSEYIETYFEDLRQQLGHRLQLNDLLIKPVQRIMKYQLLLKDFLKYYTKAGRQTEDLERAVEVMCFVPKRCNDMMNVGRLQGFEGQLRAQGKLLQQDTFTFIENENS--ILSRPKERRVFLFEQLIILSEPMDRK-RGFSLPGYVYKNSIKISCLSIEDRCPEDPCRLVLTSRNIDGSLQKFILRASSSEIRTSWANDIIQMLETQRNFLNALQSPIEFQRKEIKSLSLGKSMTASASLNSGLRP--YSSASIDRQTLPCLQSWHS----------------SQPSTPP---------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6P720-1", "uniprot_id": "ARHGP_RAT", "id": "Q6P720-1", "name": "Rho guanine nucleotide exchange factor 25", "aln": "--MKPPDRPTPGRTDRILGVMGGMLRACAVPGQEGPQERDP------LGPGSTKTESECTEEDQTGEREREVLAWAPQPESYSIAG---------SEGSMSASAVSGLAALSGPSSGLSSHPCSPVPPGPVTGLRRWLDHSKHCLSVETEADSGQTR-------------QCENWMLEPTLT---------------------------------TGQELPELTLLTTLLEGPGVKAQPAEEET-------------LSQAPKNEEEQKKTALERSMFVLSELVETERMYVDDLGQIVEGYMATMATQGVPESLRGR--DRIVFGNIQQIYEWHRDYFLQELQQCLKDPDWLAQLFIKHERRLHMYVVYCQNK-PKSEHVLSEFGDSYFEELRQQLGHRLQLSDLLIKPVQRIMKYQLLLKDFLKYYRRAGMDTEELEQAVEVMCFVPKRCNDMMSLGRLRGFEGKLTAQGKLLGQDTFLVTEPEAGGLLSSRGRERRVFLFEQIVIFSEALGGGGRGGTQPGYVYKNSIK----------------------------------ASDPAVSQAWIKQVAQILESQRDFLNALQSPIEYQRRESQTNSLGRSGGPGVGSPGRM-----AQVSMHTPINGSLPSLLLLPRGEVPRAPLPLDTQALSETPLTPYDPP-----------------------------------------------------------ALPTVNSPPGQARLAKLDEDEL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CWR0-1", "uniprot_id": "ARHGP_MOUSE", "id": "Q9CWR0-1", "name": "Rho guanine nucleotide exchange factor 25", "aln": "--MKPPDRPTPGRTDRILGVMGGMLRACAVPGQEGPPERDP------LGPGSTKTESDCIEEDQTGQREPEVLAWAPQPESYSIAV---------SEGSMSASAVSGLAALSGPSSGLSSDPCSPIPPGPVTGLRRWLDHSKHCLSVETEAESGQTG-------------QCENWTLGPTLT---------------------------------TGQELPELTLLTTLLEGPGDKAQPAEEET-------------LSQAPKNEEEQKKMALERSMFVLGELVETERTYEDDLGQIVEGYMATMATQGVPESLRGR--DRIVFGNIQQIYEWHRDYFLQELQQCLKDPDWLAQLFIKHERRLHMYVVYCQNK-PKSEHVLSEFGDSYFEELRQQLGHRLQLNDLLIKPVQRIMKYQLLLKDFLKYYRRAGKDTEELEQAVEVMCFVPKRCNDMMSLGRLRGFEGKLTAQGKLLGQDTFLVTEPEAGGLLSSRGRERRVFLFEQIIIFSEALGGGGRGGAQPGYVYKNSIKVSCLGLEGNLQGNPCRFALTSRGPEGGIQRYVLQASDPAVSQAWIKQVAQILESQRDFLNALQSPIEYQRRESQTNSLGRPGGPWVGSPGRMRPGDLAQASMHTPINGSLPSLLLLPRGEVSRVLLPLDTQALSDTPQTPHDSP-----------------------------------------------------------ALPTVNTPPCQARLAKLDEDEL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86VW2-1", "uniprot_id": "ARHGP_HUMAN", "id": "Q86VW2-1", "name": "Rho guanine nucleotide exchange factor 25", "aln": "--MRG-------------GHKGG---RCACPRVIR------------------KVLAKCGCCFARGGRE-----------SYSIAG---------SEGSISASAASGLAAPSGPSSGLSSGPCSPGPPGPVSGLRRWLDHSKHCLSVETEADSGQAG-------------PYENWMLEPALA---------------------------------TGEELPELTLLTTLLEGPGDKTQPPEEET-------------LSQAPESEEEQKKKALERSMYVLSELVETEKMYVDDLGQIVEGYMATMAAQGVPESLRGR--DRIVFGNIQQIYEWHRDYFLQELQRCLKDPDWLAQLFIKHERRLHMYVVYCQNK-PKSEHVVSEFGDSYFEELRQQLGHRLQLNDLLIKPVQRIMKYQLLLKDFLKYYNRAGMDTADLEQAVEVMCFVPKRCNDMMTLGRLRGFEGKLTAQGKLLGQDTFWVTEPEAGGLLSSRGRERRVFLFEQIIIFSEALGGGVRGGTQPGYVYKNSIKVSCLGLEGNLQGDPCRFALTSRGPEGGIQRYVLQAADPAISQAWIKHVAQILESQRDFLNALQSPIEYQRRESQTNSLGRPRGPGVGSPGRIQLGDQAQGSTHTPINGSLPSLLLSPKGEVARALLPLDKQALGDIPQAPHDSPP----------------------------------------------------------VSPTPKTPPCQARLAKLDEDEL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1ZAQ4-1", "uniprot_id": "A1ZAQ4_DROME", "id": "A1ZAQ4-1", "name": "DH domain-containing protein", "aln": "MELSLFTLNLFDVVSVVLTFLVIFLVQILNVYLHILDDNAD------------------------------------------------------NGKSIDVVDKAPAKECPLLESQSPSSPIATTLPKSQASSNGKLEKQISLLDSDSGISLSSIN-------------TCSTTAANSSPTYR-------------------------------APNGFHSFPSHTLSFETLGDEYHEDEDTLS-------------LENLFPCDQTEIYASKKISFIIDELIQTEVNYVNNLKKGMLNYGQLKDVEDLPEALSGETKQKMLLGNIKEILELHEKEILPLMLRNQRDLKGLFDEFAAHFEKNSFYCYVSFTMGKKSSMQLRQDNRLWLQTYQTQIKDKLGIDSFLVQPIQRLTRYPLLLQQFISEFYKSGISCKPVLTAVCKLETRMRRALDVVNQAEEIPNIEELNELDVLQLGNFRRATEFDAQHFPTRKKYRSKVFLFDRCLVCTEVRKKR--------LAYRQHYN----------------------------WEHVELQRPLDSVSSNANKIINLLVKQEEGGSSVGSKREEYSFMAAEASVVKQWLQATHKIIEIARNEHARRNTFSLPMDLVLGVVLAIWLIWQYL-----------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . * .. . .* : . . * *. . .. : : . . . . : : . . :: . * :: ::: **::** * :* : .* .:** : *. :::::***::* : *.. :* : : : . * : * * .: :* . . **. : : ::: : *: .:* :..:*::*:**: :* ***::* . : ::* . : ** : :*. *::. .. :: . * : * : : . :****:: :: :* ::: : : ..: ::* .*.: .:: * * *: : : : . : . ", "identical_positions": 55, "similar_positions": 132, "identity": "7.28%" }, { "cls_id": "homologset.agr.MGI:1277176", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CR22-1", "uniprot_id": "TMM42_MOUSE", "id": "Q9CR22-1", "name": "Transmembrane protein 42", "aln": "---------MAAGPQSSGAAVS----------AAAYPDSPVELPARLQKG--AMRRRFWGVFNCLCAGAFG---ALAAAAAKLAFGSQVNIGLCVLGIVAMASANSLMWTFFSRGLSFSMSSAIASVTVTFSNILCSAILGYLLYGECQEILWWGGVFLILCGLTLIHRKFPPTWK--ESKEQ-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q69YG0-1", "uniprot_id": "TMM42_HUMAN", "id": "Q69YG0-1", "name": "Transmembrane protein 42", "aln": "---------MAERPGPPGGAVS----------ATAYPDTPAEFPPHLQAG--AMRRRFWGVFNCLCAGAFG---ALAAASAKLAFGSEVSMGLCVLGIIVMASTNSLMWTFFSRGLSFSMSSAIASVTVTFSNILSSAFLGYVLYGECQEVLWWGGVFLILCGLTLIHRKLPPTWKPLPHKQQ-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3Z8L0-1", "uniprot_id": "D3Z8L0_RAT", "id": "D3Z8L0-1", "name": "", "aln": "ARFGAGFPASADSPHPPGSALAGLTSGGGVRSSRLWRAQRASWRPGLSPRGPPCLRPLTLTHPWSYPLAYRRARCGAASGACSTVCAPVNIGLCVLGIIAMASTNSLMWTFFSRGLSFSMSSAIASVTVTFSNILCSAILGYVLYGECQEILWWGGVFLILCGLTLIHRKFPPDWK--ESKQQ-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A0R4IAX4-1", "uniprot_id": "A0A0R4IAX4_DANRE", "id": "A0A0R4IAX4-1", "name": "", "aln": "-----------MLPGVFYALMAG------------FLAALASSSAKLSLG--------ADYLKDVCETGLKIWTDRQGNSDDATACDWLHIPLRLLCGGLLFTCNAVMWTFFSKALRHSSSSARATVTTTASNFISSAFLGHVIFGETHATLWWVGIILTLTGLFVLHGSTPQAPQENVDKKHE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . :: : .. . *. . . . : : : * :* : : *::******:.* .* *** *:**.* **::.**:**::::** : *** *::* * ** ::* . * : *:: ", "identical_positions": 39, "similar_positions": 41, "identity": "21.2%" }, { "cls_id": "homologset.agr.MGI:1277178", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q658Y4-1", "uniprot_id": "F91A1_HUMAN", "id": "Q658Y4-1", "name": "Protein FAM91A1", "aln": "----------------------MNIDVEFHIRHNYPWNKLPANVRQSLGNSQREYEKQVVLYSIRNQLRYRNNLVKHVKKDERRYYEELLKYSRDHLMLYPYHLSDIMVKGLRITPFSYYTGIMEDIMNSEKSYDSLPNFTAADCLRLLGIGRNQYIDLMNQCRSSKK----FFRRKTARDLLPIKPVEIAIEAWWVVQAGYITEDDIKICTLPEKCAVDKIIDSGPQLSGSLDYNVVHSLYNKGFIYLDVPISDDSCIAVPPLEGFVMNRVQGDYFETLLYKIFVSIDEHTNVAELANVLEIDLSLVKNAVSMYCRLGFAHKKGQVINLDQLHSSWK--------NVPSVNRLKSTLDPQK----------------------------MLLSWDGGE----------------SRSPVQEA-SSATDTDTNSQEDPADTASVSSLSLSTGHTKRIAFLFDSTLTAFLMMGNLSPNLKSHAVTMFEVGKLSDESLDSFLIELEKV---QSTGEGEAQRYFDHALTLRNTILFLRHNKDLVAQTAQPDQPNYGFPLDLLRCESLLGLDPATCSRVLNKNYTLLVSMAPLTNEIRPVSSCTPQHIGPAIPEVSSVWFKLYIYHVTGQGPPSLLLSKGTRLRKLPDIFQSYDRLLITSWGHDPGVVPTSNVLTMLNDALTHSAVLIQGHGLHGIGETVHVPFPFDETELQGEFTRVNMGVHKALQILRNRVDLQHLCGYVTMLNASS--------------QLADRKLSDASDERGEPDLASGSDVN------------------------GSTESFEMVIEEATIDSATKQ-TSGATTE---------------ADWVPLELCFGIPLFSSELNRKVCRKIAAHGLCRKESLQNLLHSSRKLSLQVLNFVHSFQEGASILDIHTEPSFSSLLSQSSCADMGVPLPAKNLIFKDGVLSEWSGRSPSSLLIANLHLQ---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3UVG3-1", "uniprot_id": "F91A1_MOUSE", "id": "Q3UVG3-1", "name": "Protein FAM91A1", "aln": "----------------------MNIDVEFHIRHNYPWSKLPTNVKQSLGNSQREYEKQVVLYSIRNQLRYRNNLVKHVKKDERKYYEELLKYSRDHLMLYPYHLSDIMVKGLRITPFSYYAGIMEDIMNSEKSYDSLPNFTAADCLRLLGIGRNQYIDLMNQCRSSKK----FFRRKTARDLLPMKPVEIAIEAWWVVQAGYITEDDIKICTFPEKGAIDKIIDSGPQLSGSLDYNVVHSLYNKGFIYLDVPISDDSCIAVPPLEGFVMNRVQGDYFETLLYKIFVSIDEHTNVAELANVLEIDLSLVKNAVSMYCRLGFAHKKGQVINLDQLHSSWK--------NVPSVNRLKSTLDPQK----------------------------MLLSWDGGE----------------SRSPVQEA-SSATDTDTNSQEDPADTASVSSLSLSTGYTKRIAFLFDSTLTAFLMMGNLSPNLKSHAVTMFEVGKLSDESLDSFLIELEKV---QSTGEGEAQRYFDHALTLRNTILFLRHNKDLVAQTSQPDQPNYGFPLDLLRCESLLGLDPATCSRVLNKNYTLLVSMAPLTNEIRPVSSCTPQHIGPAIPEVSSVWFKLYIYHVTGQGPPSLLLSKGTRLRKLPDIFQGYDRLLITSWGHDPGVVPASNVLTMLNDALTHSAVLIQGHGLHGVGETVHIPFPFDEAELQGEFTRASMGVHKALQILRSRVDLQHFCGYVTMLNASS--------------QLASRKLSEASDERGEPDLASSSDVN------------------------GSTESFEMVIEEASTDLATKP-NSGATAE---------------ADWVPLELCFGIPLFSSELNRKVCQKIATHGLCRKESLQSLLHSSRKLSLQVLNFVHSFQEGAATLDLHAEPGFSSVLSQSPCADMGVPLPAKNLMFKDGVLSEWSGRSPSSLLIASLHL----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6TEP1-1", "uniprot_id": "F91A1_DANRE", "id": "Q6TEP1-1", "name": "Protein FAM91A1", "aln": "----------------------MNTDVEFHIRQNYPWNKLPANVKQSLGNSQREYDKQVLLYSIRNQLRFRNNLVRHVKKDERKYYEELLKYSREHLMLYPYHLSDIMVKGLRVTPFSYYISIMEDIMNCEKSYDSLPNFTAADCLRLLGIGRNQYIDLMNQCRSSKK----FFRRKSARDLLPAKPVEITVEPWWVVQTGYITEDDIRICSVAEKAAIDKMIDSGPQLAGSMEYNVVLSLYNRGYIYLDVPISDDSCISVPPLEGFVMNRVQGDYFETLLYKIFVSIDEQTNVSELANVLEIDLGLVKNAVSMYCRLGFAIKKGQVISPDQLHPSWK--------SAPSVNRLKGTMDPQK----------------------------MLLSWEGG-------------------SPVMEAGSSATDTDTTSLED-QDTASVSSLSIPAAPTKRIAFLFDSTLTAFLMMGNLSPNLKSHAVTMFEVGKLSDETLDSFLMELEKV---ESTAEGEAQRYFDHALTLRNTILFLRYNKDLTPDQG-PDVPNIGLPLDLLRCESLLGLDPATCSRVLNKNYKLLVSMAPLSNEIRPISSCTPQHIGPAIPEVSSIWFKLYLYSVTGQGPPSLLLSKGSRLRKLPDIFQAYDRLLITSWGHDPGVVPSSNVLTMLNDALTHSAVLIQGHGMHGHGETVHVPFPFDEEDLKGEFSYSNMCAHKALKILRDKVDLEHQCGYITMLNHN------------------NRHRRRASDADGDAELCGVLDAN------------------------GSNESFELVTEENNGDGGKKQGTEASSSE---------------DEWVPLELCFGMPLFSSELNRKVCQRIVSHKLCSKDSLQELLHSSRKLALKVLSFVQSFQDGKQPAD--PDSGVSGPLSQ-PPAESGVPLPAINLLFKDGELKEWSGRAPPSLHISAPQRDQPT", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9XZ12-1", "uniprot_id": "Q9XZ12_DROME", "id": "Q9XZ12-1", "name": "Protein FAM91A1", "aln": "MTEQEDLATSGGGNATTGSGTNCQNQLQQCVRGNVTWELLPVHLRSVLHNNQRDYEKFVFNYSLKNQLRFRGNLAAKVFRREQRYYELLIQKSINGLGAFPYHLADIVTKGLRVTPFNYYLDVLGQLLQSDKSYDTLPNFTAADCLRVLGIGRNEYLALISDMKTHTPRSLIFGSRPNPLDFLPRFPVRIHIEPWWRLDIGYVLEADIRYLSPAERGLLDDLIDFGAQPAGKCDHDVVHSLYRKGLIYLDVPISGEDRISIPPLRNFVMNRVSGDYFENLLYKIFVSADEHMTIAELAQMLQLELDSVKQAISFICRLGFAHRKEDLVN-QTNHSSWEGYNQQQTPDTPQITPLNYNLHTSSSFEFDQSPKSPKTPKEREKDKDKDSSSIGYLSSDGNTSDFSFANLNTTPQERVNNSDEQELSSELEQEDMCAPKQAAPSAAISAAVLPK-SGKRVGFLFDSTLTAFLMMGNLSPGLKNHAVTMFEVGKLCEESLDSFLAELEQVSLLDAEGEGDVSRYFAHAVILRSTICSLRH---LLPGG-----------LDLLRLECLEGLDQQTRDRVLEKKYKFIIAASPLTASLSHTFSIPYFGQFLRSSDVAPMWSKLFYNHITGYGPPSLLLCRGTVLKTLPRLFLGYGKLLVN-ILHSDAYVLNSENFRSLNSQLKNGCVLLQGYGIRTAGALHYESFPFQAADTR----QAKWAAHRAVHKLSSLLDLRQQCGYITFLNTGVPDLGCEDYELQVRLKPAQRQKRTSIAAPSKPNHVPTNEVTSFQLKSPDENHFAATPEHGPANEFTAPDCSQVLASELAKCSSRADLVSQSSVEIEEISPSVVQEEDATEEWTLLDVNFGVPLFDVDTNTRICEQLVQG-LCSDANLEALPAAASQAQVLFLDFVQQCLYFE-----------DDPARQSVQAARPLPHPRINLAFENGHVCHWNGR----------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ::: :* * .*. **.:::. * *.**:*:* *. **::****:*.**. :* : *::*** *:: * : * :****:**:.****:***.** .:: ::::.:****:***********:******:*: *:.: :: . * * .. *:** **.* :*.** :: **: * **: : .*: :*.:** *.* :*. :::** ***.:* ********.:. *::***..******.*****.******** **: .::***::*:::*. **:*:*: ****** :* :::. : *.**: ..*.:. *: .:.... ** :*. * * *. : * : :: :*::*: :. **:.******************.**.***********.:*:***** ***:* :: .**:..*** **: **.** **: * . ***** *.* *** * .***:*:*.:::: :**: .: * . .:*:.:* **: :** *******.:*: *:.** :* .*.:**:. *. . * *: : **. *.:..**:**:*:: * : .***: : : . .*:*:: * . :**.: ***:*:** . .*: : ...: :.. : :. ::: .* . . :: * :*. *:: **:***. : * ::*.::. ** . .*: * :: : : .*.**:. .. * * :* * ** *::* : .*.** ", "identical_positions": 312, "similar_positions": 265, "identity": "31.93%" }, { "cls_id": "homologset.agr.MGI:1277179", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O70628-1", "uniprot_id": "PDE9A_MOUSE", "id": "O70628-1", "name": "High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGAGSSSYRPKAIYLDIDGRIQKVVFSKYCN-------------------------------------SSDIMDLFCIATGLPRNTTISLLTTDDAMVSIDPTMPANSERTPYKVRPVAVKQVS------------------------------------------------------------EREELIQGVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELEG----------------------------------------------LKVVEIEKCKSDIKKMREELAARN-SRTNCPCKYSFLDN-KKLTP------RRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPITLRRWLLCVHDNYRNN-PFHNFRHCFCVTQMMYSMVWLCGLQEKFSQMDILVLMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAIAFQILARPECNIFASVPPEGFRQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHLTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEY---FMQSDREKSEGLPVAPFMDRDK-VTKATAQIGFIKFVLIPMFET--VTKLFPVVEETMLRPLW-ESREHYEELKQLDDAMKELQKK-TESLTSGAPENTTEKNRDAKDSEGHSPPN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8QZV1-1", "uniprot_id": "PDE9A_RAT", "id": "Q8QZV1-1", "name": "High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGAGSSSYRPKAIYLDIDGRIQKVVFSKYCN-------------------------------------SSDIMDLFCIATGLPRNTTISLLTTDDAMVSIDPTMPANSERTPYKVRPVAVKQVS------------------------------------------------------------EREELVQGVLAQVAEQFSRAFKINELKAEVANHLAMLEKRVELEG----------------------------------------------LKVVEIEKCKSDIKKMREELAARN-NRTNCPCKYSFLDN-KKLTP------RRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPITLRRWLLCVHDNYRSN-PFHNFRHCFCVTQMMYSMVWLCGLQEKFSQMDILVLMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAIAFQILARPECNIFASVPPEGFRQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHLTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEY---FMQSDREKSEGLPVAPFMDRDK-VTKATAQIGFIKFVLIPMFET--VTKLFPIVEETMLRPLW-ESREHYEELKQLDDAMKELQKK-TENLTSGATENAPEKTRDAKDNEDRSPPN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O76083-1", "uniprot_id": "PDE9A_HUMAN", "id": "O76083-1", "name": "High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGSGSSSYRPKAIYLDIDGRIQKVIFSKYCN-------------------------------------SSDIMDLFCIATGLPRNTTISLLTTDDAMVSIDPTMPANSERTPYKVRPVAIKQLSAGVEDKRTTSRGQSAERPLRDRRVVGLEQPRREGAFESGQVEPRPREPQGCYQEGQRIPPEREELIQSVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELEG----------------------------------------------LKVVEIEKCKSDIKKMREELAARS-SRTNCPCKYSFLDNHKKLTP------RRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNN-PFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEY---FMQSDREKSEGLPVAPFMDRDK-VTKATAQIGFIKFVLIPMFET--VTKLFPMVEEIMLQPLW-ESRDRYEELKRIDDAMKELQKK-TDSLTSGATEKSRERSRDVKNSEGDCA------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7UT66-1", "uniprot_id": "A0A8N7UT66_DANRE", "id": "A0A8N7UT66-1", "name": "Phosphodiesterase", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSCIYFRRHLAGGTFEGWFWWICSWLRVQVDLTVHFINMGSASSSYSPKTIYLDVDGKVQKVLFSRHCS-------------------------------------PCDIKELLCSSSNIPRNTAIMMTDPEGAIVSIDPTMPTNNPNFLYKIIPLSASQLG------------------------------------------------------------EKEDMFQNVLSQVAEQFSRAFRINELKTEVTNRLAMLEKRVELEG----------------------------------------------LKVVEIEKCKNDMRKLRDEMTSRAGARVNCPCKYNFSDDGKKLTP------RRDIPSYPKYTLSQETIEALKKPTFDVWHWEHNEMLSCLEYMYHDLGLVKEFNINPITLKRWLLGIQENYRSN-PFHNFRHCFCVSQMMYGMIHLCNLQEKLTLTDLGILMTAAVCHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILSLPECNIFANVEPEAFKQIRQAIITLILATDMARHGEILDSFKHKVDHFDFTNEEHVACLKMVLIKCCDISNEVRPTEVAEPWVDCLLEEY---FMQSDREKSEGLPVAAFMDREK-VTKPTAQIGFIKFVLIPMFET--VMKLFPQIEEIMVQPLR-DSRDHYEELKQIDDAMTEAQKKKTESLSLGGKKK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0ACD6B7S0-1", "uniprot_id": "A0ACD6B7S0_DANRE", "id": "A0ACD6B7S0-1", "name": "Phosphodiesterase", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGSSSSSYTPKTIYLDVDGKVQRVIFSRHCS-------------------------------------PCDIRDLLCSSSNIARNTAVLLIDSEGALISIDPTMPANTPNNLYKVMPHSTNQGE------------------------------------------------------------EKEDMFQNVLSQVAEQFTRAFRNSELKTEVTNRLAMLEKRVELEG----------------------------------------------LKVVEIEKCKNDLKKLKDEMTSGS-MRVNCNCKYNFTDDGKKLSP------RRDVPNYPKYTLSQETIDALKKPTFDVWHWEHNEMLSCLEYMYHDLGLVKEFNMNPITLKRWLLAIQENYRDN-PFHNFRHCFCVSQMMYGMIHLCGLQDRLTMTDMCILMTAAVCHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILSMPECNIFANIEPESFKQIRQAIITLILATDMAKHGEILDSFKQKVDNFDCTNEEHVKSLKMVLIKCCDISNEVRPTEVAEPWVDCLLEEY---FMQSDREKSEGLPVAPFMDRDK-VTKPTAQIGFIKFVLIPMFET--VMKLFPQIEEIMVQPLR-DSRDHYEELKQIDDAMSEAQKKKTESMYLGGKKK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M3B2M3-1", "uniprot_id": "A0A8M3B2M3_DANRE", "id": "A0A8M3B2M3-1", "name": "Phosphodiesterase", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGSASSAYR--MIYLEVDGRVQKVVFSRFCS-------------------------------------PCDIKELFCTATGVSRNTSISLLDSTGAMVSIDPTMPNNTERSPYKVVPVTGSQLA------------------------------------------------------------DKEELFQNVLTQVAEQFSRAFKINELKTEVTNRLAMLEKRVELEG----------------------------------------------MKVVEIEKCRSDIKKLREEMASRN--------NSSFLEDNKKLTP------RRDVPSYPKYHLSQDTVEALKQPLFDVWQWESNEMLSCLEHMYHDLGLVKDFNINPITLKRWLLCIHDNYRNN-PFHNFRHCFCVTQMMYSMIYLCGLQEKFTQVDILILMTAAVCHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQIFSQPDCNIFASFDPEAFKQIRQGTITLILATDMARHGEIMDSFKQKVDSFDYNNEEHVTCLKMVLIKCCDISNEVRPMEVAEPWVDCLLEEY---FMQSDREKAEGLPVAPFMDREK-VTKPTAQIGFIKFVLIPMFET--VMKLFPQIEEVMVQPLR-ESRDKYEELKQIDDAMNEMQKKKTENLTTGGKKK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9I7S6-1", "uniprot_id": "PDE9A_DROME", "id": "Q9I7S6-1", "name": "High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A", "aln": "MYQDSGCSSSSSRRGSSSAAAATSTAATAAETAAAAAATTTSSSDEETLETLTIITTTITDSDIHATTTTTTVIASGTATTAAAAATTATLATLATLASNSDIEDSSPVESEDSEECEYIEIDCQTTAQEGTSPSGGSSSSGNAVLLQRSSNNLQQQQQQQQQQQQHLQLQLQQADERLLRKIGYIASRVRCLSKYYGDFRLVNPYSARRQRRQLQEILLRHSIFDPGKEHQRAIVLAAATAAIAGPLAAIDCVCGSSSISLEAVSSRSRSSELEDDHHEQDQVQEEQEQEQHQGDTEDNEEEQEHPSEKPERTDIEEEPPPAIAVTTTTTATVRRKSSSSSTISGTATVSGSVSVSASASQSFCSNNINLLEELLIQFYEEQDHRSNLTVIRHHHHQQHQQHQQQQRITNNNNNNNNCNSIQNNNNMSNPAATAAATATPSVEQPATSGTTNIHLQPTSLPDGSDNPRRRRASDCSAVQAALQNQLHCITLKNNNCG------------------KAMPFHRGSCGAAGEHLLAANSIANRATIILSKSCSNVDGDATATAATALSSTVGGGIGGIGGSIKMRASATDIETNALNGARDAIVASNNGNNGNNGNNGNNEYSILQLNNTIIQCHFNDDDFRALVKDLKRKVEYTERMNWLCLSKRPLGPPHRKSSLPKHQEVKRRFLEICDTTFSEEVRAALRLPAFDSYEWSDADVIHLMQTMFVELGFIEKFSIPVDTLREWLYEVYKHYNEV-PFHNFRHCFCVAQMMYAITRQANLLSRLGDLECLILLVSCICHDLDHPGYNNIYQINARTELALRYNDISPLENHHCSIAFRLLEHPECNIFKNFSRDTFNNIREGIIRCILATDMARHNEILTQFMEITPIFDYSNRAHINLLCMILIKVADISNEARPMDVAEPWLDRLLQEF---FAQSAAEKSEGLPVTPFMDPDK-VSKPGSQVRFIGLVLLPLFEA--LGELVPELTELIIIPVR-IALEYYRRLNDAQTKTRKSVADSNTSATSDSNSGTIDSNAAMVSTPGGASDKLSLDKGQGNSQGSGGGGGGGGGGGAGGGTGSGCGSNAAGSVSPQMPRSGSGISVKSRRSIPSQKSASRTSVDEPGGMASELHDLPEGSESGDSETATEVDVAEKTSKFKVDTEGSSNRSKSSHSTSRKSSREKRPSMIGELCSSGGGQRIRNSYGNIHGYHSNRCHFGNNRAVSLDQYSSAGNNRRLSDGLPQVISDSNVFYGRHNRSSTETTVAVGNPQDTNANTNHPVGCQLKELLARTEADSDGEGDGNGREDKKIPLVIPSMPQLATSSNGNISPTLVVTEQILPSNGSTRSSASSGRGGSGVPGGSGGSGMPGPSAGSGSSWKSRLRQFSDYFSFSFDKSNKRFGSTRSSPCPGSNSSSGRTNNNANGLGENQDGLGAGGGIKPGMCCTTITNSSGSTVKGETRGGTAGAGGGALTTMTTGNDAHQRHRAYSLDVPGMMRYSSNDSSRHPSNNTLQSAGGGAGLTTGLEVTAQRVPPSLSVEMGLASGSSSEAGPKI", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P06776-1", "uniprot_id": "PDE2_YEAST", "id": "P06776-1", "name": "3',5'-cyclic-nucleotide phosphodiesterase 2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSTLFLIGIHEIEKSQTIVQNEHYFDRVIELQDLDSLMVALYKDRVSP------------------------------------FPNVHNFETGVSIVLYDPSKFQLSVRQLDVLFKRFFPSFNISAIDHTREENLQRLEC----------------------------------------------------------VERENSICRNRITRINHWMYHHHDDTPDGINKNSYGTVNG-----------------------------------------------------NSVPTQACEANIYTLLLHLNDSKAQHLRKASVPRLIRNIEFMSF-------LSDPIEKISQEGSHYWNILSTWDFCALSLSTQELIWCGFTLIKKLSKDAKVLIADNKLLLLLFTLESSYHQVNKFHNFRHAIDVMQATW---RLCTYLLKDNPVQTLLLCMAAIGHDVGHPGTNNQLLCNCESEVAQNFKNVSILENFHRELFQQLLSEHWPQLLS-ISKKKFDFISE----AILATDMALHSQYEDRLMHENPMKQIT-------LISLIIKAADISNVTRTLSISARWAYLITLEFNDCALLETFHKAHRPEQDCFGDSYKNVDSPKEDLESIQNILVNVTDPDDIIKDHPHIPNGQIFFINTFAEVFFNALSQKFSGLKFLSDNVKINKEYWMKHKKPQ-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. : * * : . . :: : : . : :. : . :: . : . . . : . : . : : .: : . : . . * * . ::: : .*. .. : .* * : . *.. ******.: * * : . : : :* :.: **:.*** ** *..:*:* .::::* ***.* : ::: ::: . . * * : ******* * : : . : . * ::** .**** .*. .:: * : *: . .*:. * * * * .. :: * :*: : :. : : * : : : : : :. *. . . . ", "identical_positions": 61, "similar_positions": 124, "identity": "3.93%" }, { "cls_id": "homologset.agr.MGI:1277182", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LZV4-1", "uniprot_id": "A0ABK0LZV4_RAT", "id": "A0ABK0LZV4-1", "name": "Cleavage and polyadenylation specificity factor subunit 4", "aln": "MEEVIAGLQGFTFTFEQDVELQRGTGLLPFQGMDKSSSAVCNFFAKG----LCVKGMLCPLRHEQ--GEKMVVCKHWLRGLCRKSDCCNFLHQYDVSRMPVCYFHSKFGNCNNK-ECPFLHLKPVPKLQDCPWYDQGFCKEVGPLCKYRHVHQVLCPNYFIGFCPKGP-KCQFGHPKMSPILHRSN-------------------------------MKPINQLWDSTTSTGNT---------LVPHSQAKATVHHQKRWS----LPP--------ACSSRAHLAP-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "G3UWW6-1", "uniprot_id": "G3UWW6_MOUSE", "id": "G3UWW6-1", "name": "Cleavage and polyadenylation specificity factor subunit 4", "aln": "MEEVIAGLQGFTFAFELDVESQKGTGLLPFQGMDKSSSAVCNFFAKG----LCVKGMLCPLRHEQ--GEKLVVCKHWLRGLCRKSDCCDFLHQYDVSKMPVCYFHSKFGNCSNK-ECLFLHLKPVLKLQDCPWYNQGFCKEVGPLCKYRHVHQVLCPNYFTGFCPEGP-QCQFGHPKMSPPFHPSNVK-----------------------------LQPVNQPWDSTTSTGNT---------LVSPFQAKPMVHGQRRWS----LPQ--------ACSSRAHPAP-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NMK7-1", "uniprot_id": "CPS4L_HUMAN", "id": "A6NMK7-1", "name": "Putative cleavage and polyadenylation specificity factor subunit 4-like protein", "aln": "MQEVIAGLERFTFAFEKDVEMQKGTGLLPFQGMDKSASAVCNFFTKG----LCEKGKLCPFRHDR--GEKMVVCKHWLRGLCKKGDHCKFLHQYDLTRMPECYFYSKFGDCSNK-ECSFLHVKPAFKSQDCPWYDQGFCKD-GPLCKYRHVPRIMCLNYLVGFCPEGP-KCQFAQ-----------------------------------------------KIREFKLLPGSK---------I-----------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VPT8-1", "uniprot_id": "CPSF4_DROME", "id": "Q9VPT8-1", "name": "Cleavage and polyadenylation specificity factor subunit 4", "aln": "MDILLANVSGLQFKAERDLIEQVGAIPLPFYGMDKSIAAVCNFITRNG--QECDKGSACPFRHIR--GDRTIVCKHWLRGLCKKGDQCEFLHEYDMTKMPECYFYSRFNACHNK-ECPFLHIDPQSKVKDCPWYKRGFCRH-GPHCRHQHLRRVLCMDYLAGFCPEGP-SCKHMHPHFELPPLAELGKDQLHKKLPTCHYCGELGHKANSCKQYVGSLEHRNNINAMDHSGGHSGGYSGHSGHIEGADDMQSNHHSQPHGPGFVKVPTPLEEITCYKCGNKGHYANKCPKGHLAFLSNQHSHK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06102-1", "uniprot_id": "YTH1_YEAST", "id": "Q06102-1", "name": "mRNA 3'-end-processing protein YTH1", "aln": "MSLIHPDTAKYPFKFEPFLRQEYSFSLDPDR-------PICEFYNSREGPKSCPRGPLCPKKHVLPIFQNKIVCRHWLRGLCKKNDQCEYLHEYNLRKMPECVFFSKNGYCTQSPDCQYLHIDPASKIPKCENYEMGFCPL-GSSCPRRHIKKVFCQRYMTGFCPLGKDECDMEHPQFIIPDEGSKLR-----------------------------IKRDDEINTRKMDEEKE-------------RRLNAIINGEV---------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. : .. * * : : . * .:*:* * :* ** :* :. :**:*******:*.* *.:**:*:: :** * *.*: . * :. :* :**:.* * .* *. *** *. * :*: :::* *: **** * .*. : : ", "identical_positions": 53, "similar_positions": 46, "identity": "17.49%" }, { "cls_id": "homologset.agr.MGI:1277184", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZPS9-1", "uniprot_id": "D3ZPS9_RAT", "id": "D3ZPS9-1", "name": "Macrophage immunometabolism regulator", "aln": "MEMDVNGEPRSTLTTLPLPAAEGSSPGKAEAEKPRCSSTPCSPMRRTVSGYQILHMDSNYLVGFTTGEELLKLAQKCTGGEDSKGEAMPPLRSRQLDAGLARSSRLYKTRSRYYQPYEIPAVNGRRRRRMPSSGDKCTKSLPY-EPYKALHGPLPLCLLKGKRAHSKSLDYLNLDKMSIKEPADTEVLQYQLQHLTLRGDRVFARNNT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VEB3-1", "uniprot_id": "MACIR_MOUSE", "id": "Q8VEB3-1", "name": "Macrophage immunometabolism regulator", "aln": "MEVDINGDSRSTLTTLPLPVAEGSSPGKAEAEKPRCSSTPCSPMRRTVSGYQILHMDSNYLVGFTTGEELLKLAQKCTGGEDSKGEAMPALRAKQLDTGLARSSRLYKTRSRYYQPYEIPAVNGRRRRRMPSSGDKCTKPLPY-EPYKALHGPLPLCLLKGKRAHSKSLDYLNLDKMNIKEPADTEVLQYQLQHLTLRGDRVFARNNT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96GV9-1", "uniprot_id": "MACIR_HUMAN", "id": "Q96GV9-1", "name": "Macrophage immunometabolism regulator", "aln": "MEVDINGESRSTLTTLPFPGAEANSPGKAEAEKPRCSSTPCSPMRRTVSGYQILHMDSNYLVGFTTGEELLKLAQKCTGGEESKAEAMPSLRSKQLDAGLARSSRLYKTRSRYYQPYEIPAVNGRRRRRMPSSGDKCTKSLPY-EPYKALHGPLPLCLLKGKRAHSKSLDYLNLDKM-IKEPADTEVLQYQLQHLTLRGDRVFARNNT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B3DHS1-1", "uniprot_id": "MACIR_DANRE", "id": "B3DHS1-1", "name": "Macrophage immunometabolism regulator", "aln": "MEMDASGASRAPISVLP--AAEVKSTLKPEADKPRCSSTPCSPIKSTVSGYQILHMNSNYLVGFTTGEELLKLAQKWSSPDSSNTEALPSPIKKPVDLGLHRASRIYKAKSRYYQPYDIPAVNGRRRRRMPSSGDSCLKSIVSGEPSKALHGPLPLCLLKGKRVYSKSLDYLNLDKMSLREPVDTEVLQYQLQHLNLRGERVFTRNKT", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:* .* .*:.::.** ** .*. *.**:***********:: **********:******************* :. :.*: **:*. : :* ** *:**:**::*******:*****************.* *.: ** ****************.:************ ::**.************.***:***:**:*", "identical_positions": 144, "similar_positions": 41, "identity": "69.23%" }, { "cls_id": "homologset.agr.MGI:1277186", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3MQ06-1", "uniprot_id": "ATG5_RAT", "id": "Q3MQ06-1", "name": "Autophagy protein 5", "aln": "--MTDDKDVLRDVWFGRIPTCFTLYQDEITEREAEPYYLLLPRVS-------YLTLVTDKVKKHFQKVMRQEDVS-EIWFEYEGTPLKWHYPIGLLFDLLASS-SALPWNIT--------------VHFKSFPEKDLLHCPCKDAVEAHFMSCVKEADALKHKS-QVINEMQRKDHKQLWMGLQNDRFDQFWTINRKLMEYPPEENGFRYIPFRIYQTTTERPFIQKLFRPVAADGQLHTLGDLLREVCPSAVAPEDGEKKSQVMIHGIEPLLETPLQWLSEHLSYPDNFLHISIVPQPTD-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99J83-1", "uniprot_id": "ATG5_MOUSE", "id": "Q99J83-1", "name": "Autophagy protein 5", "aln": "--MTDDKDVLRDVWFGRIPTCFTLYQDEITEREAEPYYLLLPRVS-------YLTLVTDKVKKHFQKVMRQEDVS-EIWFEYEGTPLKWHYPIGLLFDLLASS-SALPWNIT--------------VHFKSFPEKDLLHCPSKDAVEAHFMSCMKEADALKHKS-QVINEMQKKDHKQLWMGLQNDRFDQFWAINRKLMEYPPEENGFRYIPFRIYQTTTERPFIQKLFRPVAADGQLHTLGDLLREVCPSAVAPEDGEKRSQVMIHGIEPMLETPLQWLSEHLSYPDNFLHISIVPQPTD-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H1Y0-1", "uniprot_id": "ATG5_HUMAN", "id": "Q9H1Y0-1", "name": "Autophagy protein 5", "aln": "--MTDDKDVLRDVWFGRIPTCFTLYQDEITEREAEPYYLLLPRVS-------YLTLVTDKVKKHFQKVMRQEDIS-EIWFEYEGTPLKWHYPIGLLFDLLASS-SALPWNIT--------------VHFKSFPEKDLLHCPSKDAIEAHFMSCMKEADALKHKS-QVINEMQKKDHKQLWMGLQNDRFDQFWAINRKLMEYPAEENGFRYIPFRIYQTTTERPFIQKLFRPVAADGQLHTLGDLLKEVCPSAIDPEDGEKKNQVMIHGIEPMLETPLQWLSEHLSYPDNFLHISIIPQPTD-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1RDC0-1", "uniprot_id": "F1RDC0_DANRE", "id": "F1RDC0-1", "name": "Autophagy protein 5", "aln": "MIMADDKDVLRDVWFGRIPACFTLSPDETTEREAEPYYLLLPRVS-------YLTLVTDKVKKHFLKVMKAEDVE-EMWFEHEGTPLKWHYPIGVLFDLHASN-SALPWNIT--------------VHFKNFPEQDLLHCSTNSVIEAHFMSCIKEADALKHKG-QVINDMQKKDHKQLWMGLQNDKFDQFWAMNRKLMEYPTEEGGFRYIPFRIYQTMSDRPFIQTLFRPVSSEGQALTLGDLLKELFPAAIE--DEPKKFQVMIHGIEPLLETPIQWLSEHLSHPDNFLHISIIPAPSD-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W3R7-1", "uniprot_id": "ATG5_DROME", "id": "Q9W3R7-1", "name": "Autophagy protein 5", "aln": "--MAHDREVLRMIWEGQIGICFQADRDEIVGIKPEPFYLMISRLS-------YLPLVTDKVRKYFSRYISAEHQDGAVWFDFNGTPLRLHYPIGVLYDLLHPEEDSTPWCLT--------------IHFSKFPEDMLVKLNSKELLESHYMSCLKEADVLKHRG-LVISAMQKKDHNQLWLGLVNEKFDQFWAVNRRLMEPYGDLESFKNIPLRIY-TDDDFTYTQKLISPISVGGQKKSLADLMAELSTPVR------RAVGCRTHGIDLHEETQLQWMSEHLSYPDNFLHLSVDYKDV--------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12380-1", "uniprot_id": "ATG5_YEAST", "id": "Q12380-1", "name": "Autophagy protein 5", "aln": "-----MNDIKQLLWNGELNVLVSIDPSFLMKGSPREIAVLRIRVPRETYLVNYMPLIWNKIKSFLSFDPLTDSEK-YFWFEHNKTPIPWNYPVGVLFDCLAGKSATFTTSFENQVKDVLTFLRIHLVMGDSLPPTIIPIASSKTQAEKFWFHQWKQVCFILNGSSKAIMSLSVNEARKFWGSVITRNFQDFIEISNKISSSRP-----RHIPLIIQTSRTSGTFRISQP-TISMTGVNPTLKDIEGDILDVKEG--INGNDVMVICQGIEIPWHMLLYDLYSKLRSFDGFLYITLVPIKGGDKASSEL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:: : :* *.: . . ... :: *:. *:.*: :*::..: : . .**:.: **: :**:*:*:* . : . : : ..:* : : * .:: *:. : : . .* :. :: .::* .: . .*::* :..:: . : **: * : . .: . .:: * :* *: :: . :**: . : : .:* *.**:::: ", "identical_positions": 34, "similar_positions": 101, "identity": "11.04%" }, { "cls_id": "homologset.agr.MGI:1277193", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9NQR9-1", "uniprot_id": "G6PC2_HUMAN", "id": "Q9NQR9-1", "name": "Glucose-6-phosphatase 2", "aln": "--------MDFLHR---NGVLIIQHLQKDYRAYYTFLNFMSNVGDPRNIFFIYFPLCFQFNQTVGTKMIWVAVIGDWLNLIFKWILFGHRPYWWVQET---QIYPNHSSPCLEQFPTTCETGPGSPSGHAMGASCVWYVMVTAALSHTVCGMDKFSITLHRLTWSFLWSVFWLIQISVCISRVFIATHFPHQVILGVIGGMLVAEAFEHTPGIQTASLGTYLKTNLFLF-LFAVGFYLLLRVLNIDLLWSVPIAKKWCANPDWIHIDTTPFAGLVRNLGVLFGLGFAINSEMFLLSCRGGNNYTLSFRLLCALTSLTILQLY--HFLQIPTHEEHLFYVLSFCKSASIPLTVVAFIPYSVHMLMKQSGKKSQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Z186-1", "uniprot_id": "G6PC2_MOUSE", "id": "Q9Z186-1", "name": "Glucose-6-phosphatase 2", "aln": "--------MDFLHR---SGVLIIHHLQEDYRTYYGFLNFMSNVGDPRNIFSIYFPLWFQLNQNVGTKMIWVAVIGDWFNLIFKWILFGHRPYWWIQET---EIYPNHSSPCLEQFPTTCETGPGSPSGHAMGSSCVWYVMVTAALSYTISRMEESSVTLHRLTWSFLWSVFWLIQISVCISRVFIATHFPHQVILGVIGGMLVAEAFEHTPGVHMASLSVYLKTNVFLF-LFALGFYLLLRLFGIDLLWSVPIAKKWCANPDWIHIDSTPFAGLVRNLGVLFGLGFAINSEMFLRSCQGENGTKPSFRLLCALTSLTTMQLY--RFIKIPTHAEPLFYLLSFCKSASIPLMVVALIPYCVHMLMRPGDKKTK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9VQH1-1", "uniprot_id": "Q9VQH1_DROME", "id": "Q9VQH1-1", "name": "", "aln": "MESIVHILSDAYHTTLTRELFINEWAQERLSFGRPLWHFLSVHLEPNKMFNIIIPLCGIFSQEILVHLFTAFTLISTLNSFEKWIYPETRPLWFLREQFANNVVVKKPAVALESHQLSCEMTGGLPCAHSM--TFTVFVLILASFFFVHC-WDRFAALRSSFCRCIMYLLIIGMVVCMWLSRLYLATEFLHQCILGSYLGIRSLCTFEGNVKYLFSRPRRYAVSAVFFLGGLALSVYYVKLELNIDPHWSVREAFKWCPEPTYLRHEVGPIFALVRDLGNLMGL--ALASPLYKLEMK-----QSSFWRRCRFLGVLEFVNYGLRFSTFKQSGRFVFLTYEFLRNVIHSLVLIKYVSKFY------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * ::* . *: : :*:* :*.::* * :** :.* : .::: . .: . :* : *** ** *:::* :: ::.: .**.. :** * *..*:* : . :*:: *:: .. . :. : : .::: :: : :.: :**:::**.* ** *** *: :** . : * : :*:: :*:..* : :.** *** * ***.:* ::: : *: .***:** *:** *: * :: . : ** * : .: : * :* : . :* .* :.. .* :: :. ", "identical_positions": 76, "similar_positions": 117, "identity": "20.43%" }, { "cls_id": "homologset.agr.MGI:1277201", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GBH4-1", "uniprot_id": "A0A8I6GBH4_RAT", "id": "A0A8I6GBH4-1", "name": "", "aln": "MVAERARKAAASSNRGPGDLGAPG--PGTVALAEQCARLPSPGCCGLLALALCSLALSLLAHFRTAELQARVLRLESERGEQQMEKAILGRVNQLLDEKWKFYSRRRREAPKMSPGCNCPPGPPGPTGRPGLPGDKGAIGMPGRV---------GAPGDAGISIIGPRGPPGQPGTRGFPGFPGPIGLDGRPGHPGPKGETGLVGPRGQPGPQGQKGEKGQCGEYPHREYPSGTLAALRSNPIISLKLLPLLNSVRLAPPPVIKRRTFQGEQSQAGIQGPPGPPGPPGPIGPLGHPGLPGPIGPPGLPGPPGPKGDPGIQGYHGRKGERGLPGMPGKHGAKGAPGIAVAGMKGEPGTPGAKGEKGATGSP---GLLGQKGEKGDAGNAIGGGRGEPGPPGLPGPPGPKGEAGVDGQAGPPGQQGDKGQPGAAGEPGPTGPKGSKGEPGKGEMVDYNSSINEALQEIRTLALMGPPGLPGQTGPPGPPGTPGQRGEIGLPGPPGHDGDKGPRGKPGDMGPAGPQGPPGKDGPPGMKGEVGPPGNPGEKGETGQAGP---------------------------------PGEKGEAGEKGDPGAEVPGPPGPEGPPGPPGLQGIPGPKGEAGLDGSKGEKGSQGEKGDRGPLGLPGASGLDGRPGPPGTPGPIGVPGPAGPKGERGSKGDPGMTGPTGAAGLPGLHGPPGDKGNRGERGKKGSRGPKGDKGDQGAPGLDAPCPLGEDGLPVQGCWNK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R1N9-1", "uniprot_id": "CODA1_MOUSE", "id": "Q9R1N9-1", "name": "Collagen alpha-1(XIII) chain", "aln": "MVAERTRKAAASGSRGPGELGAPG--PGTVALAEQCARLPSPGCCGLLALALCSLALSLLAHFRTAELQARVLRLEAERGEQQMEKAILGRVNQLLDEKWKFYSRRRREAPKMSPGCNCPPGPPGPTGRPGLPGDKGAIGMPGRVGIKGQPGEKGAPGDAGMSIVGPRGPPGQPGTRGFPGFPGPIGLDGRPGHPGPKGEMGLVGPRGQPGPQGQKGEKGQCGEYPHREYPGGMLAALRSNPIMSLKLLPLLNSVRLAPPPVIKRRTFQGEQSQTGIQGPPGPPGPPGPSGPLGHPGLPGPIGPPGLPGPPGPKGDPGIQGYHGRKGERGMPGMPGKHGAKGVPGIAVAGMKGEPGTPGTKGEKGAAGSP---GLLGQKGEKGDAGNAIGGGRGEPGPPGLPGPPGPKGEAGVDGQAGPPGQQGDKGQPGAAGEQGPSGPKGAKGEPGKGEMVDYNGSINEALQEIRTLALMGPPGLPGQTGPPGPPGTPGQRGEIGLPGPPGHDGDKGPRGKPGDMGPAGPQGPPGKDGPPGMKGEVGPPGSPGEKGETGQAGPQGLDGPTGEKGEPGDEGRPGATGLPGPIGLPGFTGEKGEAGEKGDPGAEVPGPPGPEGPPGPPGLQGFPGPKGEAGLEGSKGEKGSQGEKGDRGPLGLPGASGLDGRPGPPGTPGPIGVPGPAGPKGERGSKGDPGMTGPTGAAGLPGLHGPPGDKGNRGERGKKGSRGPKGDKGDQGAPGLDAPCPLGEDGLPVQGCWNK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5TAT6-1", "uniprot_id": "CODA1_HUMAN", "id": "Q5TAT6-1", "name": "Collagen alpha-1(XIII) chain", "aln": "MVAERTHKAAATGARGPGELGAPGTVALVAARAERGARLPSPGSCGLLTLALCSLALSLLAHFRTAELQARVLRLEAERGEQQMETAILGRVNQLLDEKWKLHSRRRREAPKTSPGCNCPPGPPGPTGRPGLPGDKGAIGMPGRV---------GSPGDAGLSIIGPRGPPGQPGTRGFPGFPGPIGLDGKPGHPGPKGDMGLTGPPGQPGPQGQKGEKGQCGEYPHRECLSSMPAALRSSQIIALKLLPLLNSVRLAPPPVIKRRTFQGEQSQASIQGPPGPPGPPGPSGPLGHPGLPGPMGPPGLPGPPGPKGDPGIQGYHGRKGERGMPGMPGKHGAKGAPGIAVAGMKGEPGIPGTKGEKGAEGSPGLPGLLGQKGEKGDAGNSIGGGRGEPGPPGLPGPPGPKGEAGVDGQVGPPGQPGDKGERGAAGEQGPDGPKGSKGEPGKGEMVDYNGNINEALQEIRTLALMGPPGLPGQIGPPGAPGIPGQKGEIGLPGPPGHDGEKGPRGKPGDMGPPGPQGPPGKDGPPGVKGENGHPGSPGEKGEKGETGQAGS------------------------------PGEKGEAGEKGNPGAEVPGLPGPEGPPGPPGLQGVPGPKGEAGLDGAKGEKGFQGEKGDRGPLGLPGASGLDGRPGPPGTPGPIGVPGPAGPKGERGSKGDPGMTGPTGAAGLPGLHGPPGDKGNRGERGKKGSRGPKGDKGDQGAPGLDAPCPLGEDGLPVQGCWNK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*****::****:. ****:***** . ..* **: *******.****:***************************:********.***************::********* ******************************** *:*****:**:*************************:********: **.** ********************** .. *****. *::*****************************:.************* ***********:****************************:***********.************* **:****** *** **************:****************************.***** ****: ***** ** ****:*************..********************** ****.** ***:*************:************.*************:*** * **.******.*::* .**********:******* **************.*********:*:***** *******************************************************************************************************************", "identical_positions": 631, "similar_positions": 52, "identity": "83.47%" }, { "cls_id": "homologset.agr.MGI:1277202", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O95406-1", "uniprot_id": "CNIH1_HUMAN", "id": "O95406-1", "name": "Protein cornichon homolog 1", "aln": "MAFTFAAFCYMLALLLTAALIFFAIWHIIAFDELKTDYKNPIDQCNTLNPLVLPEYLIHAFFCVMFLCAAEWLTLGLNMPLLAYHIWRYMSRPVMSGPGLYDPTTIMNADILAYCQKEGWCKLAFYLLAFFYYLYGMIYVLVSS------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0LHJ2-1", "uniprot_id": "A0ABK0LHJ2_RAT", "id": "A0ABK0LHJ2-1", "name": "", "aln": "MAFTFAAFCYMLALLLTAALIFFAIWHIIAFDELKTDYKNPIDQCNTLNPLVLPEYLIHAFFCVMFLCAAEWLTLGLNMPLLAYHIWRYMSRPVMSGPGLYDPTTIMNADILAYCQKEGWCKLAFYLLAFFYYLYGMIYVLVSS------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35372-1", "uniprot_id": "CNIH1_MOUSE", "id": "O35372-1", "name": "Protein cornichon homolog 1", "aln": "MAFTFAAFCYMLALLLTAALIFFAIWHIIAFDELKTDYKNPIDQCNTLNPLVLPEYLIHAFFCVMFLCAAEWLTLGLNMPLLAYHIWRYMSRPVMSGPGLYDPTTIMNADILAYCQKEGWCKLAFYLLAFFYYLYGMIYVLVSS------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49858-1", "uniprot_id": "CNI_DROME", "id": "P49858-1", "name": "Protein cornichon", "aln": "MAFNFTAFTYIVALIGDAFLIFFAIFHVIAFDELKTDYKNPIDQCNSLNPLVLPEYLLHIFLNLLFLFCGEWFSLCINIPLIAYHIWRYKNRPVMSGPGLYDPTTVLKTDTLYRNMREGWIKLAVYLISFFYYIYGMVYSLIST------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38312-1", "uniprot_id": "ERV15_YEAST", "id": "P38312-1", "name": "ER-derived vesicles protein ERV15", "aln": "-MSGTGLSLFVTGLILNCLNSICQIYFTILYGDLEADYINSIELCKRVNRLSVPEAILQAFISALFLFNGYWFVFLLNVPVLAYNASKVYKK-----THLLDATDIFR--KLGRCKIECFLKLGFYLLIFFFYFYRMVTALLENDANLIS", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P53173-1", "uniprot_id": "ERV14_YEAST", "id": "P53173-1", "name": "ER-derived vesicles protein ERV14", "aln": "----MGAWLFILAVVVNCINLFGQVHFTILYADLEADYINPIELCSKVNKLITPEAALHGALSLLFLLNGYWFVFLLNLPVLAYNLNKIYNK-----VQLLDATEIFR--TLGKHKRESFLKLGFHLLMFFFYLYRMIMALIAESGDDF-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: .:: . : : . * : :*::** *.*: *. :* * ** :: : :** . *: : :*:*::**: : .: * *.* ::. * * : **..:*: **:*:* *: *: ", "identical_positions": 32, "similar_positions": 45, "identity": "21.33%" }, { "cls_id": "homologset.agr.MGI:1277207", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1Q6R0-1", "uniprot_id": "F1Q6R0_DANRE", "id": "F1Q6R0-1", "name": "C-X-C chemokine receptor type 3", "aln": "-----MNVDSKTTFSMKDFSDYTDLYNYSDYNDNESYGAGAVCTQDSSMYFDSIFKPILYSLAAVVGLLGNGLVLIVLWKKR------AGLNVTDIFILHLSLADILLLLTLPFWAVEAVKEWIFGTPLCKLTGAMFRINFYCGIYMLSCISLDRYLSIVHAVQMYSRKKPMAVHCCCMIVWFFCFLLSIPDWILLGANKDS-RRQDRTECVNSEALSDFWVLVNRLIYHFLGFIIPAIMMVFCYTSILLRLLLGSKCMQKK--RAIHVIVALVLAFFISWTPYNIALMADT-IHTNRTDNNQTSCETRTTLDVAITATSTFAYMHCCVNPILYAFVGVKFRQHLLDMLRPLGFKLKGRAG--------LVSRKSSGWSESVDTSHTSAF----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M2BKS4-1", "uniprot_id": "A0A8M2BKS4_DANRE", "id": "A0A8M2BKS4-1", "name": "", "aln": "-----MAAPSNMEVELHGLFEKNNSFDYDNYENKE-----LDCQSKAVSDALGVFIPLLYSLGILLGLLGHGLVLAVLWHKW------LNCSVMDIFIFHLSLIDSLLLLTMPLWAVDAVKGWIMGSGLCKLAGVLFKMNFYCSMLMLAFISVDCYLSIVHGVQKLSRKKPMVVHGCCLIIWLVCLLLSIPEWIFLKSISDS-TDQVKDECIYFYP-DDSWHRSSRFPHHVI-FGVGTLVLLFCCTSIMLKLQRESMCQQKKIGRKTAIIAVLVLVFLICWTPYSIAFIVNTGARPVHIDPLTGESECEWRQWTASKITAIFGLLHCTINPVIYFCFSKEFRRRSQAVIKFNACESNNNDGS-------LWDSTADNVNTTVQEEQGPLQQVNELKPKVQTQQEDT", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9JII9-1", "uniprot_id": "CXCR3_RAT", "id": "Q9JII9-1", "name": "C-X-C chemokine receptor type 3", "aln": "MYLEVSERQVLDASDIAFLLENSTSPYDYGENESD-FSDSPPCPQDFSLNFDRTFLPVLYSLLFLLGLLGNGAVAAVLLSQR------TALSSTDTFLLHLAVADVLLVLTLPLWAVDAAAQWVFGSGLCKVAGALFNINFYAGAFLLACISFDRYLSIVHATQIYRRDPWVRVALTCIVVWGLCVLFALPDFIFLSASHDQRLNATHCQYNFPQVG----RTALRVLQLVAGFLMPLLVMAYCYAHILAVLLVS---RGQRRFRAMRLVVVVVVAFAVCWTPYHLVVLVDI---LMDVGVLARNCGRESHVDVAKSVTSGMGYMHCCLNPLLYAFVGVKFK-EQMWMLLMRLGRSDQRGPQ-----RQPSSSRRESSWS--ETTEASYLGL--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88410-1", "uniprot_id": "CXCR3_MOUSE", "id": "O88410-1", "name": "C-X-C chemokine receptor type 3", "aln": "MYLEVSERQVLDASDFAFLLENSTSPYDYGENESD-FSDSPPCPQDFSLNFDRTFLPALYSLLFLLGLLGNGAVAAVLLSQR------TALSSTDTFLLHLAVADVLLVLTLPLWAVDAAVQWVFGPGLCKVAGALFNINFYAGAFLLACISFDRYLSIVHATQIYRRDPRVRVALTCIVVWGLCLLFALPDFIYLSANYDQRLNATHCQYNFPQVG----RTALRVLQLVAGFLLPLLVMAYCYAHILAVLLVS---RGQRRFRAMRLVVVVVAAFAVCWTPYHLVVLVDI---LMDVGVLARNCGRESHVDVAKSVTSGMGYMHCCLNPLLYAFVGVKFR-EQMWMLFTRLGRSDQRGPQ-----RQPSSSRRESSWS--ETTEASYLGL--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49682-1", "uniprot_id": "CXCR3_HUMAN", "id": "P49682-1", "name": "C-X-C chemokine receptor type 3", "aln": "MVLEVSDHQVLNDAEVAALLENFSSSYDYGENESDSCCTSPPCPQDFSLNFDRAFLPALYSLLFLLGLLGNGAVAAVLLSRR------TALSSTDTFLLHLAVADTLLVLTLPLWAVDAAVQWVFGSGLCKVAGALFNINFYAGALLLACISFDRYLNIVHATQLYRRGPPARVTLTCLAVWGLCLLFALPDFIFLSAHHDERLNATHCQYNFPQVG----RTALRVLQLVAGFLLPLLVMAYCYAHILAVLLVS---RGQRRLRAMRLVVVVVVAFALCWTPYHLVVLVDI---LMDLGALARNCGRESRVDVAKSVTSGLGYMHCCLNPLLYAFVGVKFR-ERMWMLLLRLGCPNQRGLQ-----RQPSSSRRDSSWS--ETSEASYSGL--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E9QJ73-1", "uniprot_id": "CXR32_DANRE", "id": "E9QJ73-1", "name": "C-X-C chemokine receptor type 3-2", "aln": "----------MDNSTTAAEVSAPTDYDYNSTSYDDDNPYAAPCSLTETWNFLGRFAPVAYILVFILALVGNILVLCVIRRYRQSRHSPCSFSLTDTFLLHLAVSDLLLAATLPFFAVEWISEWVFGKVMCKITGALFSLNVYCGVLFLACISFDRYLAIVHAINISWRRKTCHAQLACAFIWVICLGLSMVDMHFRDLVEIPGMNRMVCQIVYSEQYSKQWQIGMQLVSMVLGFILPLLVMLYCYLHIFKALCHA---TRRQKRRSLRLIISLVIVFVISWAPYNALRMTDS---LQMLGVIVKSCALNNVLDVGILVTESLGLAHCALNPLLYGLVGVKFRRELAQMCKAALGPQGCLGLVGWANGRGSSTRRPTGSFSSVETENTSYFSVMA------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . .: * * * * * ::.*:*: * *: . * *::**:: * ** *:*::**: *::* :**::*.:* :*.*.. :*: **.* ** ***. : * . * :* .*. ::: : : :. . * : ::: :* *: * :: * :: :* .* :.*:** :.: . .. . .. * :. ** :**::* .. :*: . : . : . . ", "identical_positions": 58, "similar_positions": 87, "identity": "14.29%" }, { "cls_id": "homologset.agr.MGI:1277211", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6X9T7-1", "uniprot_id": "TYOBP_RAT", "id": "Q6X9T7-1", "name": "TYRO protein tyrosine kinase-binding protein", "aln": "MGAPEPS-------WCFLFLPVLLTVGGLSPVQAQSDNYPGCECSSVSPGVLAGIVLGDLVLTLLIALAVYSLG-------------RLVSRGRGTADG-TRKQHMAETESPYQELQGQRPEVYSDLNTQRQYYR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O54885-1", "uniprot_id": "TYOBP_MOUSE", "id": "O54885-1", "name": "TYRO protein tyrosine kinase-binding protein", "aln": "MGALEPS-------WCLLFLPVLLTVGGLSPVQAQSDTFPRCDCSSVSPGVLAGIVLGDLVLTLLIALAVYSLG-------------RLVSRGQGTAEG-TRKQHIAETESPYQELQGQRPEVYSDLNTQRQYYR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43914-1", "uniprot_id": "TYOBP_HUMAN", "id": "O43914-1", "name": "TYRO protein tyrosine kinase-binding protein", "aln": "MGGLEPC-------SRLLLLPLLLAVSGLRPVQAQAQS--DCSCSTVSPGVLAGIVMGDLVLTVLIALAVYFLG-------------RLVPRGRGAAEAATRKQRITETESPYQELQGQRSDVYSDLNTQRPYYK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58HEV2-1", "uniprot_id": "A0AC58HEV2_DANRE", "id": "A0AC58HEV2-1", "name": "TYRO protein tyrosine kinase-binding protein", "aln": "MRILGPSTFPNDQLADIICSSLQLGLMTGRLSGFVEANQDCSSCYQMDIGVAVGIITCDIIVTLLIALSVYCFVSRQKKRGSLHAHGRCCSSGKAKLQQTSMRAKPIEVESPYQELYGVQSDIYSDLQQYRK---", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* *. :: .: * : . ..* :. ** .**: *:::*:****:** : * . *:. : : : : *.******* * :.::****: * ", "identical_positions": 32, "similar_positions": 32, "identity": "23.7%" }, { "cls_id": "homologset.agr.MGI:1277212", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LW98-1", "uniprot_id": "A0ABK0LW98_RAT", "id": "A0ABK0LW98-1", "name": "", "aln": "MRLFLHRDVNKPNFRLNVLNDLANNMDDLKINTEVTGAKGELQDDN-FISEKDSGVHKPKDCQT-FQKNSALTLSEELSEAQSEQALSGVQSALFIPAGTAAVPSENFTVPTGAVANGPVSRSSSTKTCSMSEGSASLTSEQSTEQLATESCSTLKSVADRQLSTPPKASQHQVLFLLSDAAHTKSPTHSITKLPTSALVGHDGQNPVGNSLKSESTLLSQAEVGGGDAAAAVVRDDRVNALAAISSGTDKFRSENDTNWDPQKEFIQFLMTSEEAVDKSPAHSKVVGLEKKRKRKMDVSKITRYTEDCGGDLGRAPGKSKVLQADFLGQSEETQAIDSQSYTLPNMKPESADGDLETVDPFQHLVYSSDKCGEGNSPVHTRTLVSNSVKKKCEESDSESPVTFSTEEPSFYPCTKCNVNFREKKHLHRHMMYHLDGNSHFRHLNVPRPYACRECGRTFRDRNSLLKHMIIHQERRQKLMEEIRELKELQDEGRSARLQCPQCVFGTNCPKTFVQHAKTHEKDKRYYCCEECNFMAVTESELECHRGTAHGAA-VKCPVVSSEVSQRKTQKKT-VKDSVTGSSRKPAPYLCKMCPFTTSARSILKKHMEYLHSSPCMDSFGNPLGLDKRKSDSLEESVDVDSTKSLAKQQSSTFPKNSALKQDAKRTFGSSPQSSTFSKFHKRPHRVQKARKSIAQSGVNACSQSRSPHKNVMIKNSTDQKPKYFHQAPREKPNAKADGGYLYRYKCDDYRTVRKSGDSYPLPLKK-EVSTLNSLHLFSSS-NSHNNFISDPHNPDAKRPENEKDHKRVAVKRVLKASK-ESSGG-EDLDSYPDFLHKMTVVVLQKLHSD-KNDSYETEDDSPWDNVELGDYRAQAMEEDAYGDLTEEHVNLLPLLKSKMEGQGPGDSAALSYDQSDGFYFEYYEDGGTNNFLQDLHDPPHLENSDTPLSKHSSVFHWTDLSLEKKSCPYCPATFETGVGLSNHVRGHLHRAGLSYEARHVVSPEQIATS------DKMQHFKRTGTGTPVKRVRKAIEKSETTSEHTCQLCGGWFDTKIGLSNHVRGHLKRLGKTKWDAHKSPICVLNEMMQNEEKYEKILKALSSRRIIPRPFVAQKLSSDDDFLSHNVLPLDEYHNGLKTEALSVSASEEEGLNFLNECDETKPDLPSGKKNQSLTLIELLKSRRIGEERN--SALSPHKIHNQTARKRFVQKCVLPLNEDSPLIYQPH------KMDLTVHSAIDCKQKKSRSRSGSKKKMLTLPHGADEVYILRCRFCGLVFRGPLSVQEDWIKHLQRHIVNANLPRTGAGMVEVTSLLKKPASITETSFSLLMAEAAS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9QA22-1", "uniprot_id": "E9QA22_MOUSE", "id": "E9QA22-1", "name": "", "aln": "MRLFLHQDVNKPKFRLKVLNDLANNMDDLKINTDITGAKEELQDDNNFISEKDSGVHKPKDCQTSFQKNSSLTRSEELSEDQSEQALSGGQSALFLPASTPAVPTENFPLPTGAVVNGPVSCSSSTKTSNMNEGSVSLTPGQPADQLAAESCSTLKAAADHQLSTPQKASQHQVLFLLSDVAHAKNPTHSIKKVPTSALVGCDVQNSVGNNMKSESTLLSQAEVGQGD-ASTVVRDDCVSALAVISSGTDEFRSENDTNWDPQKEFIQFLMTSEETVDKPPAHSKVVGLEKKRKRKMDVSKITRYTEDCYSDSGRAPGKSKILQVDFLGQNEEMQAIDSQNYTLSKVKPESAGGDLESVDTFQHLVYNSDKCGEDNSPVHTRTLISNTLKKKCEESDPESPVAFSTEEPSFYPCTKCNVNFREKKHLHRHMMYHLDGNSHFRHLNVPRPYACRECGRTFRDRNSLLKHMIIHQERRQKLMEEIRELKELQDEGRSARLQCPQCVFGTNCPKTFVQHAKTHEKDKRYYCCEECNFMAVTENELECHRGIAHGAA-VKCPVVSSEVTQRKTQKKTSVKDSVIGSSKKPATYLCKMCPFTTSARSILKKHTEYLHSSACVDSFGNPLGLDKRKNDSLEESVDVDSTKSLAKQQPSTFPKNSALKQDAKRTFGSSSQSSNFSKFHKRPHRIQKARKSIAQSGVNSCSQNKSPHKNVMVKSSTDQQPKYFHQAPREKPNARADSSYLYRHKYNNYRTIRKSGDSYPLPFKK-EVNSLNSLHLFSSS-NSHN-FISDPHNADTKRPENEKDHKRVAVKRVAKASKKESSAG-EDLDSYPDFLHKMTVVVLQKLHSD-KKDSYETEDDSSWDNVELGDYTTQAMEEEAYSDLSQEHVNLLPLFKSKIEGQGPGDSAALSYDQNDGFYFEYYEDGGTNSFLQDIHDPQHLENPETPLSKHSSVFHWTDLSLEKKSCPYCPATFETGVGLSNHVRGHLHRAGLSYEARHVVSPEQIATS------DKMQHFKRTGNGTPVKRVRKAIEKSETTSEHTCQLCGGWFDTKIGLSNHVRGHLKRLGKTKWDAHKSPICVLNEMMQNEEKYEKILKALNSRRIIPRPFVAQKLSSGDDFLSHNVLPLDEYHNGLKTEALSVSASEEEGLHFLSECGERKPELPSGRKNQSLTLIELLKSRRLGEERN--SAVSPHKTHNQTARKRFVQKCVLPLNEDSPLIYQPQ------KMDLTVHSAIDCKQKKSRSRSGSKKKMLTLPHGADEVYILRCRFCGLVFRGPLSVQEDWIKHLQRHIVNANLPRTGAGMVEVTSLLKKPASITETSFSLLMAEAAS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H582-1", "uniprot_id": "ZN644_HUMAN", "id": "Q9H582-1", "name": "Zinc finger protein 644", "aln": "MRSFLQQDVNKTKSRLNVLNGLANNMDDLKINTDITGAKEELLDDNNFISDKESGVHKPKDCQTSFQKNNTLTLPEELSKDKSENALSGGQSSLFIHAGAPTVSSENFILPKGAAVNGPVSHSSLTKTSNMNKGSVSLTTGQPVDQPTTESCSTLKVAADLQLSTPQKASQHQVLFLLSDVAHAKNPTHSNKKLPTSASVGCDIQNSVGSNIKSDGTLINQVEVGEDG-EDLLVKDDCVNTVTGISSGTDGFRSENDTNWDPQKEFIQFLMTNEETVDKAPPHSKIG-LEKKRKRKMDVSKITRYTEDCFSDSNCVPNKSKMQEVDFLEQNEELQAVDSQKYALSKVKPESTDEDLESVDAFQHLIYNPDKCGEESSPVHTSTFLSNTLKKKCEESDSESPATFSTEEPSFYPCTKCNVNFREKKHLHRHMMYHLDGNSHFRHLNVPRPYACRECGRTFRDRNSLLKHMIIHQERRQKLMEEIRELKELQDEGRSARLQCPQCVFGTNCPKTFVQHAKTHEKDKRYYCCEECNFMAVTENELECHRGIAHGAV-VKCPMVTSDIAQRKTQKKTFMKDSVVGSSKKSATYICKMCPFTTSAKSVLKKHTEYLHSSSCVDSFGSPLGLDKRKNDILEEPVDSDSTKTLTKQQSTTFPKNSALKQDVKRTFGSTSQSSSFSKIHKRPHRIQKARKSIAQSGVNMCNQNSSPHKNVTIKSSVDQKPKYFHQAAKEKSNAKANSHYLYRHKYENYRMIKKSGESYPVHFKKEEASSLNSLHLFSSSSNSHNNFISDPHKPDAKRPESFKDHRRVAVKRVIKESKKESSVGGEDLDSYPDFLHKMTVVVLQKLNSAEKKDSYETEDESSWDNVELGDYTTQAIEDETYSDINQEHVNLFPLFKSKVEGQEPGENATLSYDQNDGFYFEYYEDTGSNNFLHEIHDPQHLETADASLSKHSSVFHWTDLSLEKKSCPYCPATFETGVGLSNHVRGHLHRAGLSYEARHVVSPEQIATS------DKMQHFKRTGTGTPVKRVRKAIEKSETTSEHTCQLCGGWFDTKIGLSNHVRGHLKRLGKTKWDAHKSPICVLNEMMQNEEKYEKILKALNSRRIIPRPFVAQKLASSDDFISQNVIPLEAYRNGLKTEALSVSASEEEGLNFLNEYDETKPELPSGKKNQSLTLIELLKNKRMGEERN--SAISPQKIHNQTARKRFVQKCVLPLNEDSPLMYQPQ------KMDLTMHSALDCKQKKSRSRSGSKKKMLTLPHGADEVYILRCRFCGLVFRGPLSVQEDWIKHLQRHIVNANLPRTGAGMVEVTSLLKKPASITETSFSLLMAEAAS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2BIH4-1", "uniprot_id": "A2BIH4_DANRE", "id": "A2BIH4-1", "name": "", "aln": "------------------MSALKESAKVEENDISMSSISQDLLSNQSFSVEG----------TTSGPSVHCLHETMELLSDQGD-------------------------LLSSVSFIDSICSDGPAKAAYVNGSTSPHISDEILLDISKNVPGFLPKSLHAQNSVTTNVHFEGADPLRKEGEITIRQTLTAEDVENRGIWGFDNESPE--------------------------------------ASLDNYDDANDLGWNPQREFMKFLWDDDNGLDIEEKLSPVPSPINQKRRVPSPIVHKRRRRKEKLVLKVDPSEDPFSDLNLDSKQDHPGEGSPIEFGPVKKTRSPRKPSKLQSPIVKNTKYFNG--TAEAVKHLFPKPAKKPLSKTQKIGLIRETLSSDSEGPTFFQQ---NNDFKEKSLGQNQITCNKDTTS-------SKPFVCKECGQCYYDRSSLLNHISVHQDKGK----KLNQFHQIKDEGKDAKLQCPQCNFGTNCPNTFVQHAKTHEKDKRYYSCNKCDFVEMNEDDLRRHLYHKHGVIGADHTVWKSDGFQERKVNKSPCLNSYSPSFER-----------------------------KTKNSVGNHVEEEQVNSHSLDSGDEEPPTTEQSFSACNVLTSCAKPKARSPRLLVKFGAPDEENNLSNDKCGLLRKKKRVGESKLDKSIHTLLSRKKRRDKSGSE--------IDTHQEPAKSSTKEFLDRSLNCETTFSETSSPPSKYLKR------------SAHSKEGNTKRTSKFDVNVTCSEDAGKTHLGLEKQTLKKSPSKRKMS----TPFHNMQGQDILLDFPKCRQKFKKPQATRRRKVLINNSDILSVSSDALGPEECEMDKNANARLVKRRSSSSKASLGASASHFERNHS----------SPRVLSVKDEYKDEEISESITAVKLEPS----SDVETDLKGCPYCPAVFESGISLSNHIRGHLHRVGLKVRRAPVKSAVKVASDKVPPVRRQALSQVKTEEDTSQTDHPAELPTDCQQTELICPLCREWFDNRTGLSNHVRGHLKRLGKPTSTASKSPVIILKELMRDKKQFQLKLQVLEKKCRTTNTFYPVRLGNGLTFAST-VKRQKDDKEEKKRLEINKGSPPSDLIGILKKRRAHEEAKAKHQSLTAKKALSLTSGKDCGLEIHTCKAVPSSPGEKGDNKRNVCVHCNASFHSGISLSNHLRGYSQRKRKALQDGATLDCKQRKQRARPWSKKKAFSLMHNPEEIYRLTCRFCDLVFQGPLSVQEDWIKHLQRHIMNTAVPHTGAGMVEVTSFPKDYCPITVPHAQSSVMQTSS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. * :. . : : .::. . :* .:: * : * . * . ** . :.: : ... ..:. .. :*:. :. .: . . : : : : . * . * *.. :. . . * .: : * : .: . . * * :.. :. * : . ** .*:**:**::** .:: :* * : ::::* . .* .. *.:. . : :: :.:. .. .: : . .. . .:: * . . .:.:.*. : . ... : .:* *:*: * :*:**. :.:: : * .* .:*:.*:***: : **.***:*: :**:: : ::.::::::***:.*:****** ******:****************.*::*:*: :.*.:*. * **. .. .: .*: *.:. :*: :* * .: :*.*. : :: :.. *:. : .*. : . ..:.. : * * : . .. .:: : : : :* :.:* :: . :. .:*: *.. : .: *::. : . : . ::... . :*: *: :. * :. .. :.. .*. . : *:. * * : . . .: :: : :: : * .. *: . . . :* :: . ::*: : .: :..*. .*. :.. .. : :. ::. ::: :. .:. . :.:. ..* :*:. : *.******.**:*:.****:******.**. . * *. ::*:. : :* .*. . : .. :* * ** ***.: ***************.. * ***: :*:*:*::::::: *:.*..: ...* . :*... * * * . :: * :. .:. .: : :*.: : .. :. : . :.* ..: * * : .*:.. .: ::.. :* .::.. .* : : : * :::****:*.*:*. **** ::* *..:*:* * ****.***:*****************:*: :*:**********: *. ..** . . : :::*", "identical_positions": 253, "similar_positions": 459, "identity": "18.82%" }, { "cls_id": "homologset.agr.MGI:1277214", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B3GNI6-1", "uniprot_id": "SEP11_RAT", "id": "B3GNI6-1", "name": "Septin-11", "aln": "MAVAVGRPSNEE--LRNLSLSGHVGFDSLPDQLVNKSTSQGFCFNILCVGETGIGKSTLMD----------------------------TLFNTKFESDPATHNEP---------------GVRLKARSYELQ----------ESNVRLKLTIVDTVGFGDQINKDDSYKPIVEYIDAQFEAYLQEELKIKRSLFNYHDTRIHACLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTIAKNELHKFKSKIMSELVSNGVQIYQFPTDEET----VAEINATMSVHLPFAVVGSTEEVKIGNKMAK--ARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHTRHYELYRRCKLEEMGFKDTDPDSKPFSLQ----------------ETYEAKRNEFLGELQKKEEEMRQMFVMRVKEKEAELKEAEKELHEKFDLLKRTHQE-------------------------EKKKVEDKKKELEEEVSNFQKKKAAAQLLQSQAQQSGAQQTKKDKDKKNPWLCTE---------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C1B7-1", "uniprot_id": "SEP11_MOUSE", "id": "Q8C1B7-1", "name": "Septin-11", "aln": "MAVAVGRPSNEE--LRNLSLSGHVGFDSLPDQLVNKSTSQGFCFNILCVGETGIGKSTLMD----------------------------TLFNTKFESDPATHNEP---------------GVRLKARSYELQ----------ESNVRLKLTIVDTVGFGDQINKDDSYKPIVEYIDAQFEAYLQEELKIKRSLFNYHDTRIHACLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTIAKNELHKFKSKIMSELVSNGVQIYQFPTDEET----VAEINATMSVHLPFAVVGSTEEVKIGNKMAK--ARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHTRHYELYRRCKLEEMGFKDTDPDSKPFSLQ----------------ETYEAKRNEFLGELQKKEEEMRQMFVMRVKEKEAELKEAEKELHEKFDLLKRTHQE-------------------------EKKKVEDKKKELEEEVSNFQKKKAAAQLLQSQAQQSGAQQTKKDKDKKNPWLCTE---------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NVA2-1", "uniprot_id": "SEP11_HUMAN", "id": "Q9NVA2-1", "name": "Septin-11", "aln": "MAVAVGRPSNEE--LRNLSLSGHVGFDSLPDQLVNKSTSQGFCFNILCVGETGIGKSTLMD----------------------------TLFNTKFESDPATHNEP---------------GVRLKARSYELQ----------ESNVRLKLTIVDTVGFGDQINKDDSYKPIVEYIDAQFEAYLQEELKIKRSLFNYHDTRIHACLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTIAKNELHKFKSKIMSELVSNGVQIYQFPTDEET----VAEINATMSVHLPFAVVGSTEEVKIGNKMAK--ARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHTRHYELYRRCKLEEMGFKDTDPDSKPFSLQ----------------ETYEAKRNEFLGELQKKEEEMRQMFVMRVKEKEAELKEAEKELHEKFDLLKRTHQE-------------------------EKKKVEDKKKELEEEVNNFQKKKAAAQLLQSQAQQSGAQQTKKDKDKKNASFT-----------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P54359-1", "uniprot_id": "SEPT2_DROME", "id": "P54359-1", "name": "Septin-2", "aln": "MSVEVDFVDKKEVHLRTLKQSGHVGFDSLPDQLVNKSVQNGFVFNVMCIGETGLGKSTLMD----------------------------TLFNTSFESTPSPHTLP---------------SVKLKAHTYELQ----------ESNVRLKLTICDTVGYGDQINKDDSFKAVVDYIDAQFENYLQEELKIKRSLVTCHDSRIHICLYFICPTGHGLKSLDLVCMKKLDSKVNIIPVIAKADTISKVELQRFKAKIIQELNANGVHIYQFPTDDET----VAETNTSMNSHIPFAVVGSTEFIKVGNKLIR--ARQYPWGTVQVENETHCDFVKLREMLIRTNMEDMREKTHTRHYELYRQKRLEQMGFSDVDSDNKPISFQ----------------QTFEAKRSNHLAELQSKEEEVRQMFVQRVKEKEAELKESEKDLHAKFEKLKRDHAE-------------------------EKRKLEESRKALEEDYLDFQRRKQ--QLATAHHTLTLGKSKKK---------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32458-1", "uniprot_id": "CDC11_YEAST", "id": "P32458-1", "name": "Cell division control protein 11", "aln": "---------------------MSGIIDASSALRKRKHLKRGITFTVMIVGQSGSGRSTFIN----------------------------TLCGQQVVDTSTTILLP-----------------TDTSTEIDLQLREETVELEDDEGVKIQLNIIDTPGFGDSLDNSPSFEIISDYIRHQYDEILLEESRVRRNPR-FKDGRVHCCLYLINPTGHGLKEIDVEFIRQLGSLVNIIPVISKSDSLTRDELKLNKKLIMEDIDRWNLPIYNFPFDEDEISDEDYETNMYLRTLLPFAIIGSNEVYEMGGDVGTIRGRKYPWGILDVEDSSISDFVILRNALLISHLHDLKNYTHEILYERYRTEALSGESVAAESIRPNLTKLN---------------GSSSSSTTTRRNTNPFKQSNNINNDVLNPASDMHGQSTGENNETYMTREEQIRLEE--------------------------ERLKAFEERVQQELLLKRQELLQREKELREIEARLEKEAKIKQEE-------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q07657-1", "uniprot_id": "SHS1_YEAST", "id": "Q07657-1", "name": "Seventh homolog of septin 1", "aln": "--------------------MSTASTPPINLFRRKKEHKRGITYTMLLCGPAGTGKTAFANNLLETKIFPHKYQYGKSNASISSNPEVKVIAPTKVVSFNSKNGIPSYVSEFDPMRANLEPGITITSTSLELGGNKDQGKPEMNEDDTVFFNLIMTHGIGENLDDSLCSEEVMSYLEQQFDIVLAEETRIKRNPR-FEDTRVHVALYFIEPTGHGLREVDVELMKSISKYTNVLPIITRADSFTKEELTQFRKNIMFDVERYNVPIYKFEVDPEDDDLESMEENQALASLQPFAIITSDTRDSEGRYV-----REYPWGIISIDDDKISDLKVLKNVLFGSHLQEFKDTTQNLLYENYRSEKLSS-VANAEEIGPNSTKRQSNAPSLSNFASLISTGQFNSSQTLANNLRADTPRNQVSGNFKENEYEDNGEHDSAENEQEMSPVRQLGREIKQENENLIRSIKTESSPKFLNSPDLPERTKLRNISETVPYVLRHERILARQQKLEELEAQSAKELQKRIQELERKAHELKLREKLINQNKLNGSSSSINSLQQSTRSQIKKNDTYTDLASIASGRD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .* ..*: :.:: * :* *:::: : .: .. . : * .: :* :.. : :.: * * *:.::.. . : : .*: *:: * ** :::*. .* *:* .**:* ****.*:.:*: ::.:.. .*::*:*:::*:::: ** : *: :: .: **:* * : * * : ***:: * . * : *:**** :.:::.. .*: *:: *: ::.:::: *: ** ** *. . : . : . .: . . ::: . : ..: ::: . . *: * : . :* . . : ", "identical_positions": 63, "similar_positions": 138, "identity": "10.9%" }, { "cls_id": "homologset.agr.MGI:1277215", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZVJ8-1", "uniprot_id": "A0A8I5ZVJ8_RAT", "id": "A0A8I5ZVJ8-1", "name": "BBSome complex member BBS1", "aln": "MAATTSSPDSDSGRAESNEANSKWLDAHYDPMANIHTFSSCLALADLHGDGEYKLVVGDLGPG----GQQPRLKVLKGPTVLTESPLPALPASAATFLMDQHEPRTPALALASGPCVYVYKNLRPYFKFSLPQLPPNPLEQDLWNQAKEDRIDPLTLKEMLEDIREKAEVPLSVQSLRFLQLELNEMEAFVNQHKSKVIKRQTVITTMTTLKKNLADEDAVSCLVLGTENKELLVLDPEAFTILTK----MSLPSVPVFLEVSGQFDVEFRLTAACRDGSIYILRRDSKHPKYCIELSAQPVG--LVRVHKILVVGSTQESLHGFTHKGKKLWTVQMPAAILTMNLLEQRSRGLQAVMAALANGEVRIYRDKALLNVVRAPDAVTSLCFGRYGREDNTLIMTTRGGGLIIKILKRTAVFVEGTGEVG--------PPLAQTTKLSVPRKTRLYVDQTLREREAGTVMHRTFQTDLYLLRLRAARAYVQALESSLSPMS-ATAREPLKLHAVVQGLGPTFKLTLHLQNTSTARPVLGLQVCFLYNEAFYALPRAFFKVPLLVPGLSYPLETFVESLSS----------KGISDIIKVLVLREGQSAPLLSAHINMPVSEGLAAA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3V3N7-1", "uniprot_id": "BBS1_MOUSE", "id": "Q3V3N7-1", "name": "BBSome complex member BBS1", "aln": "MAAASSS-DSDSGRAESNEANSKWLDAHYDPMANIHTFSSCLSLADLHGDGEYKLVVGDLGPG----GQQPRLKVLKGPTVLTESPLPALPASAATFLMDQHEPRTPALALASGPCVYVYKNLRPYFKFSLPQLPPNPLEQDVWNQAKEDQIDPLTLKEMLEDIREKADVPLSVQSLRFLQLELSEMEAFVNQHKSKVIKRQTVITTMTTLKKNLADEDAASCLVLGTESKELLVLDPEAFTILAK----MSLPSVPVFLEVSGQFDVEFRLTAACRNGSIYILRRDSKHPKYCIELSAQPVG--LVRVHKVLVVGSTQESLHGFTHKGKKLWTVQMPAAILTMNLLEQRSRGLQAVMAALANGEVRIYRDKALLNVIHAPDAVTSLCFGRYGREDNTLIMTTRGGGLIIKILKRTAVFVEGTGEVG--------PPLAQTTKLSVPRKTRLYVDQTLREREAGTAMHRTFQTDLYLLRLRAARAYVQALESSLSPMS-TTAREPLKLHAVVQGLGPTFKLTLHLQNTSTARPVLGLHVCFLYNKALYALPQAFFKVPLLVPGLSYPLETFVESLSS----------KGISDMIKVLVLREGQSAPLLSAHINMPVSEGLAAA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NFJ9-1", "uniprot_id": "BBS1_HUMAN", "id": "Q8NFJ9-1", "name": "BBSome complex member BBS1", "aln": "MAAASSS-DSDACGAESNEANSKWLDAHYDPMANIHTFSACLALADLHGDGEYKLVVGDLGPG----GQQPRLKVLKGPLVMTESPLPALPAAAATFLMEQHEPRTPALALASGPCVYVYKNLRPYFKFSLPQLPPNPLEQDLWNQAKEDRIDPLTLKEMLESIRETAEEPLSIQSLRFLQLELSEMEAFVNQHKSNSIKRQTVITTMTTLKKNLADEDAVSCLVLGTENKELLVLDPEAFTILAK----MSLPSVPVFLEVSGQFDVEFRLAAACRNGNIYILRRDSKHPKYCIELSAQPVG--LIRVHKVLVVGSTQDSLHGFTHKGKKLWTVQMPAAILTMNLLEQHSRGLQAVMAGLANGEVRIYRDKALLNVIHTPDAVTSLCFGRYGREDNTLIMTTRGGGLIIKILKRTAVFVEGGSEVG--------PPPAQAMKLNVPRKTRLYVDQTLREREAGTAMHRAFQTDLYLLRLRAARAYLQALESSLSPLS-TTAREPLKLHAVVQGLGPTFKLTLHLQNTSTTRPVLGLLVCFLYNEALYSLPRAFFKVPLLVPGLNYPLETFVESLSN----------KGISDIIKVLVLREGQSAPLLSAHVNMPGSEGLAAA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VS19-1", "uniprot_id": "Q9VS19_DROME", "id": "Q9VS19-1", "name": "", "aln": "MAGAPNWLHVDT--------------AEEAPPPHLTTLTSCMALSDVQCDGYVRLLAADISLDNAAEEPTATLKVFRGLKLKHEQPLPGIPAAIESLYIDETEPKTPVIAVAIAESVLFYRHLKPYFKYTIPAQDSEDLELEVWRKLP--VVKPSAHPALLDSLKTIDHSKLSRKSQRLLQMGEQEREHFIATHKDSPVGRVGNIVAMCCIKRISSDANPPSHLVLATDTGHIMILEPQGFNLVYQGKACDDETAVPSLISVQGTFETDFCIVVATRNGGVYLLRKSQSEGQEIFKLGIPLTGLLLLPIDQTIIASTMDNRYLCYSKRGKLLYQVPMSDLPVCLLPLPLTHLGLTLVAIALRGGVVKFYLQRYLVDEFVLEETVDAMLYGRMGMEDHVLTLVTQSGGIVVKILRRVSRFEPKAGDLANKRALGDNKSIVDASILDKPKKSSIFVEQAAREKQQAKSTYGSFQVELWRLRHTAARATIDAINSSESTISGDLTHAPVKLSAEVCGSGPAFRLYLTVQNLSTFKMASNLVVLLHADRRHYTIPQTLARLPSVLPGVPLRVDFEVVAVLDPMDKLPPASLTPDNSLIRVMLMKAGQAKPLIAAAISMPQSEAAF--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.:.. . *: *. * .:: *:::*::*:*:: ** :*:..*:. . . ***::* : *.***.:**: :: ::: **:**.:*:* . .* .*::*:****:::* .: ** ::*.: :.* : :*:.:: . ** :* *:**: .* * *: **.. : * *.:* :*: :* :. * ***.*:. .:::*:*:.*.:: : . .:** ::.*.* *:.:* :..* *:*.:*:**:.... : ::*. .* *: :.: ::..: :: ::::** *: * *. : : * ** * .* .* *::* :: *:: . ::* :: :** * **:.* :.*:.**:::***:*.: * .::. . .:: *. *:*: ::*:*: **:: .. : :**.:*: ** **** ::*::** *.:* :: *:** * * * **:*:* * :** ** : . .* * : :. *::*::: ::* ::**: :: * :: . . ..:*:*:::: **: **::* :.** **. ", "identical_positions": 165, "similar_positions": 239, "identity": "26.48%" }, { "cls_id": "homologset.agr.MGI:1277216", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JWQ0-1", "uniprot_id": "A0A0G2JWQ0_RAT", "id": "A0A0G2JWQ0-1", "name": "General transcription factor IIH subunit 1", "aln": "---------------------------------------------------MATSSEEVLLIVKKVRQKKQ-------------DGALYLMAERIAWAPEGKDRFTISHMYADIKCQKISPEGKAKIQLQLVLHAGDTTNFHFSN---ESTAVKERDAVKDLLQQLLPKFKRKANKELEEKNRMLQEDPVLFQLYKDLVVSQVISAEEFWANRLNVNATESS-TSSHKQDVGISAAFLADVRPQTDGCNGLRYNLTSDIIESIFRTYPAVKMKYAETVPHNMTEKEFWTRFFQSHYFHRDR----LNTGSKDLFAECAKIDEKGLKTMVSLGVKNPMLDLTALE----DKPLDEGYG---ISSVPSTSNSKSIKENSNAAIIKRFNHHSAMVLAAGLRKQQAQNGQNGEPSSVDG------------------------NSGDTDCFQPAVKRAKLQESIEYEDLG----------NNNSVKTIALNLKKSDRYYHGPTPIQSLQYATSQDIIN----SFQSIRQEMEAYTPKLT-QVLSSSAASSTITALSPGGALMQGGTQQ---AVNQMVPNDIQSELKHLYVAVGELLRHFWSCFPVNTPFLEEKVVKMKSNLERFQVTKLCPFQEKIRRQY--LSTNLVTHIEEMLQTAYNKLHSWQSRRLMKKT---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DBA9-1", "uniprot_id": "TF2H1_MOUSE", "id": "Q9DBA9-1", "name": "General transcription factor IIH subunit 1", "aln": "---------------------------------------------------MATSSEEVLLIVKKVRQKKQ-------------DGALYLMAERIAWAPEGKDRFTISHMYADIKCQKISPEGKAKIQLQLVLHAGDTTNFHFSN---ESTAVKERDAVKDLLQQLLPKFKRKANKELEEKNRMLQEDPVLFQLYKDLVVSQVISAEEFWANRLNVNATDSS-TSSHKQDVGISAAFLADVRPQTDGCNGLRYNLTSDIIESIFRTYPAVKMKYAETVPHNMTEKEFWTRFFQSHYFHRDR----LNTGSKDLFAECAKIDEKGLKTMVSLGVKNPMLDLTSLE----DKPLDEGYS---ISSVPSTSNSKSIKENSNAAIIKRFNHHSAMVLAAGLRKQQAQNGQNGEPSSVDG------------------------NSGDTDCFQPAVKRAKLQESIEYEDLG----------NNNSVKTIALNLKKSDRYYHGPTPIQSLQYATSQDIIN----SFQSIRQEMEAYTPKLT-QVLSSSAASSTITALSPGGALMQGGTQQ---AVNQMVPNDIQSELKHLYVAVGELLRHFWSCFPVNTPFLEEKVVKMKSNLERFQVTKLCPFQEKIRRQY--LSTNLVSHIEEMLQTAYNKLHTWQSRRLMKKT---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P32780-1", "uniprot_id": "TF2H1_HUMAN", "id": "P32780-1", "name": "General transcription factor IIH subunit 1", "aln": "---------------------------------------------------MATSSEEVLLIVKKVRQKKQ-------------DGALYLMAERIAWAPEGKDRFTISHMYADIKCQKISPEGKAKIQLQLVLHAGDTTNFHFSN---ESTAVKERDAVKDLLQQLLPKFKRKANKELEEKNRMLQEDPVLFQLYKDLVVSQVISAEEFWANRLNVNATDSSSTSNHKQDVGISAAFLADVRPQTDGCNGLRYNLTSDIIESIFRTYPAVKMKYAENVPHNMTEKEFWTRFFQSHYFHRDR----LNTGSKDLFAECAKIDEKGLKTMVSLGVKNPLLDLTALE----DKPLDEGYG---ISSVPSASNSKSIKENSNAAIIKRFNHHSAMVLAAGLRKQEAQNEQTSEPSNMDG------------------------NSGDADCFQPAVKRAKLQESIEYEDLG----------KNNSVKTIALNLKKSDRYYHGPTPIQSLQYATSQDIIN----SFQSIRQEMEAYTPKLT-QVLSSSAASSTITALSPGGALMQGGTQQ---AINQMVPNDIQSELKHLYVAVGELLRHFWSCFPVNTPFLEEKVVKMKSNLERFQVTKLCPFQEKIRRQY--LSTNLVSHIEEMLQTAYNKLHTWQSRRLMKKT---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q960E8-1", "uniprot_id": "TF2H1_DROME", "id": "Q960E8-1", "name": "General transcription factor IIH subunit 1", "aln": "---------------------------------------------------MTTSSEDVLLQMGEVRYKKG-------------DGTLYVMNERVAWMAEHRDTVTVSHRYADIKTQKISPEGKPKVQLQVVLHDGNTSTFHFVNRQGQAAMLADRDKVKELLQQLLPNFKRKVDKDLEDKNRILVENPNLLQLYKDLVITKVLTSDEFWATHAKDHALKKM---GRSQEIGVSGAFLADIKPQTDGCNGLKYNLTSDVIHCIFKTYPAVKRKHFENVPAKMSEAEFWTKFFQSHYFHRDR----LTAGTKDIFTECGKIDDQALKAAVQQGAGDPLLDLKKFE----DVPLEEGFGS--VAGDRNVVNSGNIVHQN---MIKRFNQHSIMVLKTCANVTSAPSTMTNGTNNANGPVSQSAYTNGMNGKGQATATATKSSSDQVDKDEPQSKKQRLMEKIHYVDLGDPILEGDDSANGEKAKSKHFELSKVERYLNG--PVQNSMYDNHNDPMSLEEVQYKLVRNSESWLNRNVQRTFICSKAAVNALGELSPGGSMMRGFQEQ---SAGQLVPNDFQRELRHLYLSLSELLKHFWSCFPPTSEELETKLQRMHETLQRFKMAKLVPFENRAMHELSPLRSSLTQHLNQLLRTANSKFATWKERKLRNTR---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32776-1", "uniprot_id": "TFB1_YEAST", "id": "P32776-1", "name": "General transcription and DNA repair factor IIH subunit TFB1", "aln": "MSHSGAAIFEKVSGIIAINEDVSPAELTWRSTDGDKVHTVVLSTIDKLQATPASSEKMMLRLIGKVDESKKRKDNEGNEVVPKPQRHMFSFNNRTVMDNIKMTLQQIISRYKDADIYEEKRRREESAQHTETPMSSSSVTAGTPTPHLDTPQLNNGAPLINTAKLDDSLSKEKLLTNLKLQQSLLKGNKVLMKVFQETVINAGLPPSEFWSTRIPLLRAFAL---STSQKVGP-YNVLSTIKPVASSENKVNVNLSREKILNIFENYPIVKKAYTDNVPKNFKEPEFWARFFSSKLFRKLRGEKIMQNDRGDVIIDRYLTLDQEFDRKDDDMLLHPVKKIIDLDGNIQDDPVVRGNRPDFTMQPGVDINGNSDGTVDILKGMNRLSEKMIMALKNEYSRTNLQNKSNITNDEEDE------------------------DNDERNELKIDDLNESYKTNYAIIHLKRN---AHEKTTDNDAKSSADSIKNADLKVSNQQMLQQLSLVMDNLINKLDLNQVVPNNEVSNKINKRVITAIKINAKQAKHNNVNSALGSFVDNTSQANELEVKSTLPIDLLESCRMLHTTCCEFLKHFYIHFQSGEQKQASTVKKLYNHLKDCIEKLNELFQDVLNGDGESMSNTCTAYLKPVLNSITLATHKYDEYFNEYNNNSN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::*.: :* : :* .* : :: : :* . : * * . : . . : . * . ..: . . ::. : : : : : . *.* .:*: :: :* : *:::::: *:. :...***:.: . .*.:* .*: ::* :.. * :. **: : * **..** ** : :.** ::.* ***::**.*: *:: * : . *:: : :: :. . .*: .: :: * *: .* *. . . ::*:..: *.* . . . .. : ...: : : . . .* ..:..*: .:.: : . :*. : . . .: . . .: . . . *. *::: . : . :* *: . : *: : *:*:**: * .: :: . *: *:: : : .. . ::: :*.: .:.. . ", "identical_positions": 67, "similar_positions": 197, "identity": "9.96%" }, { "cls_id": "homologset.agr.MGI:1277218", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q68FQ7-1", "uniprot_id": "RPAP3_RAT", "id": "Q68FQ7-1", "name": "RNA polymerase II-associated protein 3", "aln": "MTSTSKAVELQLQVKHNAEELQDFMRDLEHWEKTMRQKDLELRRQSGVPEENLPPIRNGSFRKKKKR-KTKDSSKKTKEENTKNRIKSFDYDAWAKLDVDSILDELDKEDSTHDSVSQESESDEDGVRVDSQKALVLKEKGNKYFKQGKYDEAIECYTKGMDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAIALSRSYTKAYARRGAARFALQKLEDARKDYVKVLELEPDNFEATNELRKIDQALTSKENSHP-KDIAAVIKPAEGERKANEDQRGRQKAIAEKDLGNGFFKEGKYEQAIECYTRGIAADSTNALLPANRAMAYLKVQKYEEAERDCTQAILLDGSYSKAFARRGTARTFLGKINEAKQDFETVLLLEPGNKQAVTELSRIKKELIEKGRWDDVFLDSTQRHNVVKPVDSPHR-GSPKALKKVFIEETGNLIESVDAPESS-ATVPESD-----RAAVAVDTGRKKDFSQGDSVSSGETPRAKVLKIEAVGDSSAPQAQVDVKQGVRQSVSEKTSVRVAQTPGQLAAVVLPPVPANSFQLESDFRQLRSSPEMLYQYVKKIEPSLYPKLFQKNLDPDVFNQIIKILHDFYVEREKPALIFEVLERLSQLRRFDMAVMFMSGTERELTKVLFNHLEKSELKE-DSVEELKKRYGGG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D706-1", "uniprot_id": "RPAP3_MOUSE", "id": "Q9D706-1", "name": "RNA polymerase II-associated protein 3", "aln": "MTSASKAVELQLQVKHNAEELQDFMRDLEHWEKDMKEKDLELRRQGGVAEENLPPIRNGNFRKKKKKGKAKESSRKTKEENTKNRIKSYDYDAWAKLDVDRILDELDKEDSTHDSLSQESESDEDGIRVDSQKALVLKEKGNKYFKQGKYDEAIECYTKGMDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAIALSRTYTKAYARRGAARFALQKLEDARKDYEKVLELEPDNFEATNELRKINQALTSKENSGPGAAAAAESKPAAGESKPTGGQQGRQKAIAEKDLGNGFFKEGKYEQAIECYTRGIAADRTNALLPANRAMAYLKIQRYEEAERDCTQAIVLDGSYSKAFARRGTARTFLGKINEAKQDFETVLLLEPGNKQAATELSRIKKELIEKGHWDDVFLDSTQRHHVVKAVDNPPR-GSPKALKKVFIEETGNLIETVDAPDSS-ATVPESD-----RATAAVGTGTKKNPSEGVSLPAGDRPRAKVLKIEAVSDTSAPQAQVGVKQDARQPGSEKASVRAEQMPGQLAAAGLPPVPANSFQLESDFRQLRSSPEMLYQYVKNIEPSLYPKLFQKNLDPDVFNQIIKILHDFYIEREKPALIFEVLERLSQLRRFDMAVMFMSGPERKLTNVLFNHLEKSDLKE-DSVEELKKRYGG-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H6T3-1", "uniprot_id": "RPAP3_HUMAN", "id": "Q9H6T3-1", "name": "RNA polymerase II-associated protein 3", "aln": "MTSANKAIELQLQVKQNAEELQDFMRDLENWEKDIKQKDMELRRQNGVPEENLPPIRNGNFRKKKKG-KAKESSKKTREENTKNRIKSYDYEAWAKLDVDRILDELDKDDSTHESLSQESESEEDGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELRKISQALASKENSYP-KEADIVIKSTEGERKQIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKELIEKGHWDDVFLDSTQRQNVVKPIDNPPHPGSTKPLKKVIIEETGNLIQTIDVPDSTTAAAPENNPINLANVIAATGTTSKKNSSQDDLFPTSDTPRAKVLKIEEVSDTSSLQPQASLKQDVCQSYSEKMPIEIEQKPAQFATTVLPPIPANSFQLESDFRQLKSSPDMLYQYLKQIEPSLYPKLFQKNLDPDVFNQIVKILHDFYIEKEKPLLIFEILQRLSELKRFDMAVMFMSETEKKIARALFNHIDKSGLKD-SSVEELKKRYGG-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V3E9-1", "uniprot_id": "Q9V3E9_DROME", "id": "Q9V3E9-1", "name": "RNA polymerase II-associated protein 3", "aln": "MSAQEKAFELQRQVRQNAREYENSVKDLYSWEQDIKNKEKELQKSPLSAANKDLPVR------------SHVQTDKSRKESPS--------------------------SSAASSPTEKQDLPVDPVAQQYKKANDIKDRGNTYVKQGEYEKAIVAYSTAIAVYPHDPIYHINRALCYLKQESFDQCVEDCEAAIALDKLCVKAYYRRMQANESLGNNMEALKDCTTVLAIEPKNIEAKRSLARINDRLR---------------------------------KIATKS-GPNFTPDR----------------------PGMIEILPIEKPAYKRSKKAMRSVPVVD-------------------------------VVSPRATIDDSNQLRISDEDIDKIFNSNCGIIEEVKKTNPKPTPMPDTSGPPKAETIAKTSKEVKPTKQTAVKVAPAVETPKET-------ETRKDTKIVPESDNEAKPSAPKKTAVEVPKVQTQVSPPKTTIERSPEVNTVQTEKIEQASSNNAMSPSPIERFLPPAPTSTAQFHVTWKELSGPQ--KYQYLKSIEVPNLCKILGAGFDSDTFADLLRTIHDFFVPNKEPN-TAAVLLEISKNDEFTILAMLMSAEEKKMVSSILNAIKNWPSKNPAVLDNLFKEYGVA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:: .**.*** **::**.* :: ::** **: :::*: **::. . :: *:* :: .: *:::*... .*: .* :::.: * : : :** :*::**.*.***:*::** .*:..: . *::*: *** .*:: :.* . .**: *:**.: .*** ** *. :* : :* ** ** :**.*:**...* :*.: * *: *. * .* : *. : :: *:.::: .. ::* ::.* . :: :*..* *:* .: : . :: *. * *..*. . . .: : : . :. . .*:. . .* : .: .: . . .:* *:: ... : . : .. *. . : . . . *** *:.: *:. :::* .. ***:*.** . *:: .:*.*.* :::: :***:: .::* :* .:*: .* : .*:** *:::. ::* :.: *: :::* *.** ", "identical_positions": 124, "similar_positions": 214, "identity": "18.54%" }, { "cls_id": "homologset.agr.MGI:1277220", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XIB5-1", "uniprot_id": "CCD86_RAT", "id": "Q5XIB5-1", "name": "Coiled-coil domain-containing protein 86", "aln": "MGTPLRRSRRLEGLNPLSLENLPDPEVSRAKRALVDFKSNPEETRELESP-RVPPLDLVSPQPQPETSPESPCP--------------------------------------------------------------------------------KQDAGFGSPQRQPEPHPGSLQLHQDLGLDSPAGQTESNPESPQR-----EQSSKLSPTQ---DSEVAHAKEEVIP-----------RSPEPCPGQQAPGPEPSQPAQELAFQAPSSPERQLEPSKLPPAGESVTGSLDLKKRVIASPQAPASKKLK--EELPVIPKGKPKSGRVWKDRSKKRFSQMVQDKPLRTSWQRKMKERQERKLAKDFARHLEEEKQRRRQEKKERRAENLRRRLENERKAEIVQVIRNPAKLKKAKKKQLRSIQKRDTLALLQKQPPQRPVAKV------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JJ89-1", "uniprot_id": "CCD86_MOUSE", "id": "Q9JJ89-1", "name": "Coiled-coil domain-containing protein 86", "aln": "MDTPLRRSRRLEGLKPLSPENLPVPEVSRAKRALVDFKSNSEETGELKST-RVPPLSLPSPGPQPETSPGSPCPPLSLPSPGPQPETSPGSPCPPLSLPSPGPQPETSPGSPCPPLSLPSPGPQPETSPGSPCPPLSLPSPGPQPEASPGSPGPRQDADDGSPQRQPEPHPGSLQPHQDLGLESPAGQTESSPESPQR-----EQPSKLPPPQGELDSEAAHAKEEVIP-----------GSPEPCPGQQAPGPEPSQPAQELTVQAPSSPERQLEPGKLPPAGETVTESLNLKKRVIASPQAPASKKLKEKEELPVIPKGKPKSGRVWKDRSKKRFSQMVQDKPLRTSWQRKMKERQERKLAKDFARHLEEEKQRRRQEKKERRAENLRRRLENERKAEIVQVIRNPAKLKKAKKKQLRSIEKRDTLALLQKQPPQRPVAKV------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H6F5-1", "uniprot_id": "CCD86_HUMAN", "id": "Q9H6F5-1", "name": "Coiled-coil domain-containing protein 86", "aln": "MDTPLRRSRRLGGLRPESPESLTS--VSRTRRALVEFESNPEETREPGSPPSVQRAGLGSPERPPKTSPGSPRL--------------------------------------------------------------------------------QQGAGLESPQGQPEPGAASPQRQQDLHLESPQRQPEYSPESPRCQPKPSEEAPKCSQDQGVLASELAQNKEELTPGAPQHQLPPVPGSPEPYPGQQAPGPEPSQPLLELTPRAPGSPRGQHEPSKPPPAGETVTGGFGAKKRKGSSSQAPASKKLN-KEELPVIPKGKPKSGRVWKDRSKKRFSQMLQDKPLRTSWQRKMKERQERKLAKDFARHLEEEKERRRQEKKQRRAENLKRRLENERKAEVVQVIRNPAKLKRAKKKQLRSIEKRDTLALLQKQPPQQPAAKI------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VWF8-1", "uniprot_id": "Q9VWF8_DROME", "id": "Q9VWF8-1", "name": "Coiled-coil domain-containing protein 86", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSESAP--------------------------------ETVP------------AKKPAKAKKAAKPENS------------------------------------------------------------IPRGQPKSNRPWKT-PKQKFSKIKKT-VNRLSFEKKTALRDELRYIKERSKEIKDKRKEDAVQKHQRRVENAERRLANERRSEVVQVIKNPAKLKRMKKKQMRMIEKRD--------VSQVKVV--------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A2BG55-1", "uniprot_id": "A2BG55_DANRE", "id": "A2BG55-1", "name": "Coiled-coil domain-containing protein 86", "aln": "-MSTCKESDGGDAANLEGSDNEVDSPVVSRTRSGRRIRTPAAKAPVRRTRKSVVPEEAIDIHEEPTEDAKTDQS-----------------------------------------------------------------------------------SSLTEAACPDVNTAAAAEASQESAVSDNALLIASDQTSEKE--------------------NVANNKNIGSS-----------GPVNPEKANKAKKRTHSESSEKKS---------------------------------------------------NVVPLGKPKSGRVWKDRKKQRFSALLRDKPLCTSWEKKMEAKREKQQVKLYHQQLKDEQAREKEEKKKRREEHLKRRAENERKAEIVQVIKNTAKIKRMKKKQLRKIEKRDTLSMVQKTPPKVKKSTEKTTSSS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . :* .::* * :* *:***.* ** *::** : : *:::* : * : * :.::::: . :*::** *: .** ***::*:****:*.**:*: ****:* *:*** .: ", "identical_positions": 45, "similar_positions": 42, "identity": "10.02%" }, { "cls_id": "homologset.agr.MGI:1277223", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O70305-1", "uniprot_id": "ATX2_MOUSE", "id": "O70305-1", "name": "Ataxin-2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------MRSSTAAVQRPAAGDPEPRRPAG-WAARRSLPRTARRGGRGG----AVAYPSAGPPPRGPGAPPRGPRSPPCASDCFGSNGHG--ASRPGSRRLLGVCGPPRPFVVVLLALA----PAATPARACPPGVRASPPRSGVSSSARPAPGCPRPACEPVYGPLTMSLKPQPQ---------------------PPAPATGRKPGG-GLLSSPGAAP-ASAAVTSASVVPAPAAPVASSSAAAGGGRPGLGRGRNSSKGLPQPTISFDGIYANVRMVHILTSVVGSKCEVQVKNGGIYEGVFKTYSPKCDLVLDAAHEKSTESSSGPKREEIMESVLFKCSDFVVVQFKDTDSSYARRDAFTDS-ALSAKVNGEHK-EKDLEPWDAGELTASEELE-LENDVSNGWDPNDMFRYNEENYGVVSTYDSSLSSYTVPLERDNSEEFLKREARANQLAEEIESSAQYKARVALENDDRSEEEKYTAVQRNCSDREG---HGPNTRDNKYIPPGQRNREV-LSWGSGRQSSPRMGQPGPGSMPSRAASHTSDFNPNAGSDQRVVNGG-VPWPSPCPSHSSRPPSRYQSGP-NSLPPRAATHTRPPSRPPSRPSRPPSHPSAHGSPAPVSTMPKRMSSEGPPRMSPKAQRHPRNHRVSAGRGSMSSGLEFVSHNPPSEAAAPPVAR------TSPAGGTWSSVVSGVPRLSPKTHRPRSPRQSSIG-NSPSGPVLASPQAGIIPAEAVSMPVPAASPTPASPASNRALTPSIEAKDSRLQDQRQNSPAGSKENVKASETSPSFSKADNKGMSPVVSEHRKQIDDLKKFKNDFRLQPSSTSES-MDQLLSKNRE--GEKSRDLIKDK-------TEASAKDSFIDSSSSSSNCTSGSSKTNSPSISPSMLSNAEHKRGPEVTSQGVQTSSP---ACKQEKDDREEKKD-TTEQVRKSTLNPNAKEFNPRSFSQP-KPSTTPTSPRPQAQPSPSMVGHQQPAPVYTQPVCFAPNMMYPVPVSPGVQP--LYPIPMTPMPVNQAKTYRAGKVPNMPQQRQDQHH---QSTMMHPASAAGPPIVATPP-AYSTQYVAYSPQQFPNQPLVQHVPHYQSQHPHVYSPVIQGNARMMAPPAHAQPGLVSSSAAQFGAHEQTHAMYACPKLPYNKETSPSFYFAISTGSLAQQYAHPNAALHPHTPHPQPSATPTGQQQ--SQHGGSHPAPSPVQHHQHQ-----AAQALHLASPQQQSAIYHAGLAPTPPSMTPASNTQSPQSSFP-AAQQTVFTIHPSHVQPAYTTPPHMAHVPQAHVQSGMVPSHP--TAHAP-MMLMTTQPPG-PKAALAQSALQPIPVSTTAHFPYMTHPSVQAHHQQQL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZRB2-1", "uniprot_id": "A0A8I5ZRB2_RAT", "id": "A0A8I5ZRB2-1", "name": "", "aln": "MQVSAPKAPAGHPLCCIWWGGNQGPRRGLRTPGQPTVPVREAGPAAEDKHSLLEGQTRLSEGGSPTALPRPRRANAAQRCARSSRVPDRPPSRLTFDFRLTLPTSGKESPPLCFASPRPPGRVAPYASASPAPMRPSTDAAQRPAAG-PEPRRLSG-WAARRSLPRTARRGGRGG----AVAYPSAGPPPRGPGAPPRGPRSPPCASDCFGSNGNG--ASRPGSRRLFGVCGPPRPFVVVLLPLA----PATAPARACPLGVRASPPRSGVSS-ARPAPGCPRPACEPVYGPLTMSLKPQPQ---------------------PPAPASGRKPGG-GLLSSPGAAP-ASAASTSSSVVPAPAAPVASSSAVAGGGRPGLGRGRNSSKGLPQPTISFDGIYANVRMVHILTSVVGSKCEVQVKNGGVYEGVFKTYSPKCDLVLDAAHEKSTESSSGPKREEIMESVLFKCSDFVVVQFKDTDSSYARRDAFTDS-ALSAKVNGEHK-EKDLEPWDAGELTASEELEALENDVSNGWDPNDMFRYNEENYGVVSTYDSSLSSYTVPLERDNSEEFLKREARANQLAEEIESSAQYKARVALENDDRSEEEKYTAVQRNCSDREG---HGTNTRENKYIPPGQRNREV-ISWGSGRQSSPRMGQPGPGSMPSRATSHTSDFNPNAGSDQRVVNGG-VPWPSPCPSPSSRPPSRYQSGP-NSLPPRAATPTRPPSRPPSRPSRPPSHPSAHGSPAPVSTMPKRMSAEGPPRMSPKAQRHPRNHRVSAGRGSMSSGLEFVSHNPPSEAAAPPVAR------TSPAGGTWSSVVSGVPRLSPKTHRPRSPRQNSAG-NSPSGPVLASPQAGITPAEAVSMPVPAASPTPASPASNRALTPSIEAKDSRLQDQRQNSPAGNKENIKASETSPSFSKAENKGVSPVISEHRKQIDDLKKFKNDFRLQPSSTSES-MDQLLSKNRE--GEKSRDLMKDK-------TEASAKDSFIDSGSSS--CTSSSSKTNSPSASPSVLSNAEHKRGPEVTSQGVQTSSP---ACKQEKDDREERKD-TTEQVRKSTLNPNAKEFNPRSFSQP-KPSTTPTSPRPQAQPSPSMVGHQQPAPVYTQPVCFAPNMMYPVPVSPGVQP--LYPIPMTPMPVNQAKTYRAGKVPNMPQQRQEQHH---QSTMMHPASAAGPPIVATPPAAYSTQYVAYSPQQFPNQPLVQHVPHYQSQHPHVYSPVIQGNARMMAPPAHAQPGLVSSSAAQFGAHEQTHAMYACPKLPYNKETSPSFYFAISTGSLAQQYAHPNATLHPHPPHPQPSATPTGQQQ--SQHGGSHPAPSPVQHHQHQ-----AAQALHLASPQQQSAIYHAGLAPTPPSMTPASNTQSPQSSFP-AAPQTVFTIHPSHVQPAYTTPPHMAHVPQAHVQSGMVPSHP--TAHAP-MMLMTTQPPGGPQAALAQSALQPIPVSTTAHFPYMTHPSVQAHHQQQL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99700-1", "uniprot_id": "ATX2_HUMAN", "id": "Q99700-1", "name": "Ataxin-2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------MRSAAAAPRSPAVATESRRFAAARWPGWRSLQRPARRSGRGGGGAAPGPYPSAAPPPPGPGPPPSRQSSPPSASDCFGSNGNGGGAFRPGSRRLLGLGGPPRPFVVLLLPLASPGAPPAAPTRASPLGARASPPRSGVSL-ARPAPGCPRPACEPVYGPLTMSLKPQQQQQQQQQQQQQQQQQQQQQQQPPPAAANVRKPGGSGLLASPAAAPSPSSSSVSSSSATAPSSVVAATS---GGGRPGLGRGRNSNKGLPQSTISFDGIYANMRMVHILTSVVGSKCEVQVKNGGIYEGVFKTYSPKCDLVLDAAHEKSTESSSGPKREEIMESILFKCSDFVVVQFKDMDSSYAKRDAFTDS-AISAKVNGEHK-EKDLEPWDAGELTANEELEALENDVSNGWDPNDMFRYNEENYGVVSTYDSSLSSYTVPLERDNSEEFLKREARANQLAEEIESSAQYKARVALENDDRSEEEKYTAVQRNSSEREG---HSINTRENKYIPPGQRNREV-ISWGSGRQNSPRMGQPGSGSMPSRSTSHTSDFNPNSGSDQRVVNGG-VPWPSPCPSPSSRPPSRYQSGP-NSLPPRAATPTRPPSRPPSRPSRPPSHPSAHGSPAPVSTMPKRMSSEGPPRMSPKAQRHPRNHRVSAGRGSISSGLEFVSHNPPSEAATPPVAR------TSPSGGTWSSVVSGVPRLSPKTHRPRSPRQNSIG-NTPSGPVLASPQAGIIPTEAVAMPIPAASPTPASPASNRAVTPSSEAKDSRLQDQRQNSPAGNKENIKPNETSPSFSKAENKGISPVVSEHRKQIDDLKKFKNDFRLQPSSTSES-MDQLLNKNRE--GEKSRDLIKDK-------IEPSAKDSFIENSSSN--CTSGSSKPNSPSISPSILSNTEHKRGPEVTSQGVQTSSP---ACKQEKDDKEEKKD-AAEQVRKSTLNPNAKEFNPRSFSQP-KPSTTPTSPRPQAQPSPSMVGHQQPTPVYTQPVCFAPNMMYPVPVSPGVQP--LYPIPMTPMPVNQAKTYRA--VPNMPQQRQDQHH---QSAMMHPASAAGPPIAATPP-AYSTQYVAYSPQQFPNQPLVQHVPHYQSQHPHVYSPVIQGNARMMAPPTHAQPGLVSSSATQYGAHEQTHAMYACPKLPYNKETSPSFYFAISTGSLAQQYAHPNATLHPHTPHPQPSATPTGQQQ--SQHGGSHPAPSPVQHHQHQ-----AAQALHLASPQQQSAIYHAGLAPTPPSMTPASNTQSPQNSFP-AAQQTVFTIHPSHVQPAYTNPPHMAHVPQAHVQSGMVPSHP--TAHAP-MMLMTTQPPGGPQAALAQSALQPIPVSTTAHFPYMTHPSVQAHHQQQL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2CF31-1", "uniprot_id": "A2CF31_DANRE", "id": "A2CF31-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSMKPQAG--------------------------GNRKPGG----SNSGAAAASGTGGAGG-----------------GVGRQNMGRGRNNAKG-PSTAVAFNGVYANMRMVHVLTSVVGTKCELKVKNGLIYEGVFKTYGPECDIVLDAAHRKSVEPNAGPRREDIVESIIFKSSDVVVVHFKDVDLNYAKKDNFTDS-AVSARVNGEHK-EKDLEPWDGGEQHISGSMESLDTDLSNGWDPDEMFKYNEETYGVKSTYDSSLSSYTVPLERDNSEEFLKREARASQLAEEIEASATYKARVALENDDRSEEEKYTAVVR--GEREL---HSLN-RENKYIPPSQRNREAGMSWGAGRQVSPRLVQCSSG--PPTPRSGPHDYN---TIDQRVVNGGAQPWPSRCPSPSSRPPSRYQSGPTNSLPPRAATPTRPPSRPPSRPSRPLSHPSAHGTSGPLSNMPKRLSSEGPPRMSPKSQRTPRPHRVASCRGGGPPPSDYMSQGASVEVSAPPPTR------NSPSGGTWSSVVSG-------AHRPRSPRQNSIGGEAPNSSCLSSPQAGTVPVDSVTASTTATSPTAANPATNLEASPIEEAKESRVLETRQNSPNANKENVKPIEASPGIARSIGKGSPSMASDHRKQIDNLKKFSAAFRLQPSSSSDPGFEAMGTKPPRDLGEKPKDQAAEKGSVDSTGLKASTESSISEETSSPVSVTSAGSKAGTPSLSPSS-AVPEQKRGPDVTSQGVQTTSPLANAVTKDKDEKEDKNDPVAESVRKSTLNPNAKEFNPRVFCSPPKPATTPTLTRPQGQPSPSIV-VQQPPTVYGQTMF---QMYPLTPVSPGVQPPAMYHVQVPHMTMSQTKSYRSGKVQNMPQQRPDQHHPPGTSTMMHSATAAGPPIVAPSP-AYSTQYFTCSPQQFASQPLVQQMPHYQSQAQHVFSPVIQGSARMITPPTHAQPSLVSSSTTQYG--EQTHTMYG-KNFPS---TMTKLNKPTYSTPIPQQFPHPSSTLHPHPQHPQPSATPTGQPQQGTQHGGSHPAPSPVQHQQHQAAAAAAAQAIHLGNPQQQ--QMYSALAATPPSMTPGPNPQSPQASFP-SAQQAVY-IHPQHG----YNPNHMAHVQQAHMQSGMVPPHHGNPSHPPTMMLMATQAPAGPQPALPQGTLNPIPVSSGTHF-YSTLTPVQAHHQQQL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8SWR8-1", "uniprot_id": "ATX2_DROME", "id": "Q8SWR8-1", "name": "Ataxin-2 homolog", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNNNSKRK---------------------------TRPTGG----GASGGISRYNSNDNSLR-------------------PTNNKAGAGGGNGGAAVRPSAQGVYNNTFFMHSATALVGSVVEVRLRSGNIYEGVFRTFSGNFDIALELP--ACIKSKNLPEEGKVPKHIIFPADTVVTIVAKDFDSQYATAGAFQTDGAISDKCNGARPDEKELEPWDSG---ANGDIDIELDSAANGWDPNEMFRKNENTFGVTSTFDDSLASYTVPLDKGDSLEFKEAEAKAEKLAAEIENNPTCRDRLDLENGD--EEALFAAVERPSTEQDQRGDRGDRERNDRDREREERDRDRDRDRGNKPRGAGDFQLRETMSSDRYITKQTRSITGPQLSHVGMSSQGSGRDRDTRGDGSMMMQSGGGSGQGGSTQSTAALMLAGGLKGVGPAPSANASADSSSKYSGGSMVKRKTVPQGGKVMRNNVPTGGSNVSVSQGGNGNSVGQNKGGYQPSMGMPSQYSYQGNSQIMHGSSQYRNQSHMGGANKLNGDSNANTNKPLPQRQMRQYQGSQSNSSLNYGGEPQSLGKPVHGSHGGHPGQNSNSPPLQTAGPQQQQQQQQQQQQQQQQQQPPQQQQHQNIQPQGQNTQPARQVRTRDNQMQELRQFGQDFQLAPSNTSPPQQQQQQQQQQQ------QHQVQQQ-----------------------------QQRALQQSASPPQQQQQQQQQQQHVVLHQVPQTHL--------HQAALSQPHYVPQQQPQQAPLPQQQHVPHHMQQKAQQQQLVETQHQHVQKQHQSQPQVQQPPPQLLQDPSQQPLPIYHTMPPPQTSP----VVVTSPVLLEQPPPQPMPVVQQQQTQQLATPK--------PEVSPAPPSSNTTTPTGIASTPTAGVIASAGSEKTTPAAPTPTSNSATVPTGTAATAGGATGTTPVVKKHVLNPSAKPFTPRGPSTPNPSRPHTPQTPVPMTNIYTTTG-GHVPPAANQPIYVMQPQHPFPPQTHPQAGQPP--RLRRSNYPPMAASQMHVSAS----AATGQPLITAGPIPQFIQYGHAPHQQQFQSHTYAPMQMRVYPDQPQQLQFMTQTPQSTTPSPGQPHQQFHPPPQPSPAGGGPQP---AFTPPTQAATYQLMCVHPQSLLANHYFPPPTPQHPQQNQQQYQIVMQQHQPQ-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53297-1", "uniprot_id": "PBP1_YEAST", "id": "P53297-1", "name": "PAB1-binding protein 1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKGNFRKR--------------------------------------DSSTNSRKGGNSDSN--------------------YTNGGVPNQNNSSMFYENPEITRNFD-DRQDYLLANSIGSDVTVTVTSGVKYTGLLVSCNLESTNGIDVVLRFPRVADSG--VSDSVDDLAKTLGETLLIHGEDVAELELKN----IDLSLDEKWE-----------------------------------------------------------------NSKAQETTPARTNIEKERVNGESNEVTKFRTDVDISGSGREIKERKLEKWTPEEGA---------EHFDINKGKALEDDSASWDQFAVNEKKFGVKSTFDEHLYTTKIN-----------------------------------------------------------------KDDPNYSKRLQEAERIAKEIESQG----------TSGNIHIAEDRGIIIDDSGLDEED---------------------------------------LYSGVDRRGDELLAALKSNSKPNSNKGNRYVPPTLRQQPHHMDPAIISSSNS---------------NKNENAVSTDTSTPAAAGAPEGKPPQKTSKNKKSLSSKEAQIEELKKFSEKFKVPYDIPKDMLEVLKRSSS---------------------------------------------TLKSNSSLPPKPISKTPSAKTVSPTTQISAGKSE------------------------------SRRSGSNISQGQSSTGHTTRSSTSLRRRNHGSFFGAKNP-------------------------------------HTNDAKRVLFGKSFNMFIKSKEAHD---------EKKKGDDASENMEP------FFIEKPYFTAPTWLNTIEESYKTFFPDEDTAIQEAQTRFQQRQLNSMGNAVPGMNPAMGMNMGGMMGFPMGGPSASPNPMMNGFAAGSMGMYMPFQPQP-MFYHPSMPQMMPVMGSNGAEE----GGGNISPHVPAGFMAAG-------PGAPMGAFGYPGGIPFQGMMGSGPSGMPANGSAMHSHGHS---------------------RNYHQTSHHGHHNSSTSGHK---------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. : : .. . . . . . .. : : : :*: : : .* * *:: : . : :: .. . . : . : : :* . ::. : : ...: * .:. .: : * . : * :: .. .* : : :. :. : .: . . : . . .. . : :. .:* :: . . . ... * :: . .. : .:: . . . . : *:::*::* *:: . .. . * .* : . : . . : .. . : : * ::* .:. : : . . . . * : : : . . . . :* :* * .. .. . . : . . . . .. : : ... : ", "identical_positions": 24, "similar_positions": 165, "identity": "1.6%" }, { "cls_id": "homologset.agr.MGI:1277225", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6PI25-1", "uniprot_id": "CNIH2_HUMAN", "id": "Q6PI25-1", "name": "Protein cornichon homolog 2", "aln": "MAFTFAAFCYMLTLVLCASLIFFVIWHIIAFDELRTDFKNPIDQGNPARARERLKNIERICCLLRKLVVPEYSIHGLFCLMFLCAAEWVTLGLNIPLLFYHLWRYFHRPADGSEVMYDAVSIMNADILNYCQKESWCKLAFYLLSFFYYLYSMVYTLVSF------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5BJU5-1", "uniprot_id": "CNIH2_RAT", "id": "Q5BJU5-1", "name": "Protein cornichon homolog 2", "aln": "MAFTFAAFCYMLTLVLCASLIFFVIWHIIAFDELRTDFKNPIDQGNPARARERLKNIERICCLLRKLVVPEYSIHGLFCLMFLCAAEWVTLGLNIPLLFYHLWRYFHRPADGSEVMYDAVSIMNADILNYCQKESWCKLAFYLLSFFYYLYSMVYTLVSF------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35089-1", "uniprot_id": "CNIH2_MOUSE", "id": "O35089-1", "name": "Protein cornichon homolog 2", "aln": "MAFTFAAFCYMLTLVLCASLIFFVIWHIIAFDELRTDFKNPIDQGNPARARERLKNIERICCLLRKLVVPEYSIHGLFCLMFLCAAEWVTLGLNIPLLFYHLWRYFHRPADGSEVMYDAVSIMNADILNYCQKESWCKLAFYLLSFFYYLYSMVYTLVSF------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5BL21-1", "uniprot_id": "CNIH2_DANRE", "id": "Q5BL21-1", "name": "Protein cornichon homolog 2", "aln": "MAFTFAAFCYMLTLVLCAALIFFVIWQIIAFDELRTDFKNPIDQSNPTRARERILNIERICNLLRRLVVPEYSIHGLFCLMFMCAGEWVTLGLNIPLLLYHLWRFFHRPADGSEVMYDPVSVMNADILNYCQKESWCKLGFYLLSFFYYLYSMVYALVSF------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P49858-1", "uniprot_id": "CNI_DROME", "id": "P49858-1", "name": "Protein cornichon", "aln": "MAFNFTAFTYIVALIGDAFLIFFAIFHVIAFDELKTDYKNPIDQ----------------CNSLNPLVLPEYLLHIFLNLLFLFCGEWFSLCINIPLIAYHIWRYKNRPVMSGPGLYDPTTVLKTDTLYRNMREGWIKLAVYLISFFYYIYGMVYSLIST------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38312-1", "uniprot_id": "ERV15_YEAST", "id": "P38312-1", "name": "ER-derived vesicles protein ERV15", "aln": "-MSGTGLSLFVTGLILNCLNSICQIYFTILYGDLEADYINSIEL----------------CKRVNRLSVPEAILQAFISALFLFNGYWFVFLLNVPVLAYNASKVYKK-----THLLDATDIFR--KLGRCKIECFLKLGFYLLIFFFYFYRMVTALLENDANLIS", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P53173-1", "uniprot_id": "ERV14_YEAST", "id": "P53173-1", "name": "ER-derived vesicles protein ERV14", "aln": "----MGAWLFILAVVVNCINLFGQVHFTILYADLEADYINPIEL----------------CSKVNKLITPEAALHGALSLLFLLNGYWFVFLLNLPVLAYNLNKIYNK-----VQLLDATEIFR--TLGKHKRESFLKLGFHLLMFFFYLYRMIMALIAESGDDF-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: :: . : : * : :*.:*: *.*: * :. * ** :: : :*: . *. : :*:*:: *: : :: : *.. ::. * * : **..:*: **:*:* *: :*: ", "identical_positions": 26, "similar_positions": 48, "identity": "15.66%" }, { "cls_id": "homologset.agr.MGI:1277234", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZJ07-1", "uniprot_id": "D3ZJ07_RAT", "id": "D3ZJ07-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSERRRSAVALSSRAHAFSVEALIGSNKK--------------------------RKLRDWE--------------------------------------EKGLDLSMEALSPTGPLGDTDDPATHGLEPHPDSEQSTGSDSEVLTERTSCSFSAHTDLASGAAGSVPVAMSSMEEIQVELQCADLWKRFHDIG--------------------------------------------------------------------------------------TEMIITKAGRRMFPAMRVKITGLDP--------------------HQQYYIAMDIVPVDNKRYRYVYHSSKWMVAGNADSPVPPRVYIHPDSLASGDTWMRQVVSFDKLKLTNN---------------------------------------------------------------------ELDDQGHIILHSMHK--------------------------------------------------------------------------------YQPRVHVIRKDFSSDLSP-----TKPVPVGDGVKTFNFP---------ETVFTTVTAYQN--------------------------------------------------------------------------------------------QQITRLKIDRNPFAKGFRDSGRNR-------------------------------------TGLEAIMETYAFWRPPVR-----TLTFEDFTTMQKQQGGSTGTSPSTSSTGTPSPSASSHLLSPSCSPPTFHLAPN-----------------------------------------------------TFNVGCRESQLCNLN--LSDYPPCARSNMAALQSYPGLSDSGYNRLQS--GTASATQPSETFMPQRTPSLISG-----------IPTPPSLPSNSKMEAYGGQLGSFPTSQFQYVMQAGN---------AASSSSSPHMFGGS--HMQQSSYNAFSLHNPYNLYGYN---------FPTSPRLAASPEKLSASQSTLLCSSPSNGAFGERQYLPTGMEHSVHMISPSTNNQQATNTCDGRQYGAVPGSSSQMSVHMV---------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70306-1", "uniprot_id": "TBX15_MOUSE", "id": "O70306-1", "name": "T-box transcription factor TBX15", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSERRRSAVALSSRAHAFSVEALIGSNKK--------------------------RKLRDWE--------------------------------------EKGLDLSMEALSPAGPLGDTDDPATHGLEPHPDSEQSTGSDSEVLTERTSCSFSTHTDLASGAAGPVPAAMSSMEEIQVELQCADLWKRFHDIG--------------------------------------------------------------------------------------TEMIITKAGRRMFPAMRVKITGLDP--------------------HQQYYIAMDIVPVDNKRYRYVYHSSKWMVAGNADSPVPPRVYIHPDSLASGDTWMRQVVSFDKLKLTNN---------------------------------------------------------------------ELDDQGHIILHSMHK--------------------------------------------------------------------------------YQPRVHVIRKDFSSDLSP-----TKPVPVGDGVKTFNFP---------ETVFTTVTAYQN--------------------------------------------------------------------------------------------QQITRLKIDRNPFAKGFRDSGRNR-------------------------------------TGLEAIMETYAFWRPPVR-----TLTFEDFTTMQKQQGGSTGTSPTTSSTGTPSPSASSHLLSPSCSPPTFHLAPN-----------------------------------------------------TFNVGCRESQLCNLN--LSDYPPCARSNMAALQSYPGLSDSGYNRLQS--GTASATQPSETFMPQRTPSLISG-----------IPTPPSLPSNSKMEAYGGQLGSFPTSQFQYVMQAGN---------AASSSSSPHMFGGS--HMQQSSYNAFSLHNPYNLYGYN---------FPTSPRLAASPEKLSASQSTLLCSSPSNGAFGERQYLPTGMEHSMHMISPSTNNQQATNTCDGRQYGAVPGSASQMSVHMV---------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96SF7-1", "uniprot_id": "TBX15_HUMAN", "id": "Q96SF7-1", "name": "T-box transcription factor TBX15", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSERRRSAVALSSRAHAFSVEALIGSNKK--------------------------RKLRDWE--------------------------------------EKGLDLSMEALSPAGPLGDTEDAAAHGLEPHPDSEQSTGSDSEVLTERTSCSFSTHTDLASGAAGPVPAAMSSMEEIQVELQCADLWKRFHDIG--------------------------------------------------------------------------------------TEMIITKAGRRMFPAMRVKITGLDP--------------------HQQYYIAMDIVPVDNKRYRYVYHSSKWMVAGNADSPVPPRVYIHPDSLASGDTWMRQVVSFDKLKLTNN---------------------------------------------------------------------ELDDQGHIILHSMHK--------------------------------------------------------------------------------YQPRVHVIRKDFSSDLSP-----TKPVPVGDGVKTFNFP---------ETVFTTVTAYQN--------------------------------------------------------------------------------------------QQITRLKIDRNPFAKGFRDSGRNR-------------------------------------TGLEAIMETYAFWRPPVR-----TLTFEDFTTMQKQQGGSTGTSPTTSSTGTPSPSASSHLLSPSCSPPTFHLAPN-----------------------------------------------------TFNVGCRESQLCNLN--LSDYPPCARSNMAALQSYPGLSDSGYNRLQS--GTTSATQPSETFMPQRTPSLISG-----------IPTPPSLPGNSKMEAYGGQLGSFPTSQFQYVMQAGN---------AASSSSSPHMFGGS--HMQQSSYNAFSLHNPYNLYGYN---------FPTSPRLAASPEKLSASQSTLLCSSPSNGAFGERQYLPSGMEHSMHMISPSPNNQQATNTCDGRQYGAVPGSSSQMSVHMV---------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A2R8QEJ0-1", "uniprot_id": "A0A2R8QEJ0_DANRE", "id": "A0A2R8QEJ0-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSDRRRSAAALSSRAHAFSVEALIGTNKK--------------------------RKLRGWE--------------------------------------EKELELSMESLASNGQLGDGEDPAN-CLDIDPDSEASPGSDGEGLAERTSCSFGSPADLTSAACDPSPS--ASMEEIQVELQCADLWKRFHDIG--------------------------------------------------------------------------------------TEMIITKAGRRMFPAMRVKIVGLDP--------------------HQQYYIAMDIVPVDNKRYRYVYHSSKWMVAGNADSPVPPRVYIHPDSLASGDTWMRQVVSFDKLKLTNN---------------------------------------------------------------------ELDDQGHIILHSMHK--------------------------------------------------------------------------------YQPRVHVIRKDFSSELSP-----TKPVPTGEGVKTFSFP---------ETVFTTVTAYQN--------------------------------------------------------------------------------------------QQITRLKIDRNPFAKGFRDSGRNR-------------------------------------TGLEAIMETYAFWRPPVR-----TLTFEDFTNMQKQQGGSTGTSPTTSSTGTPSPSGATHLLSPSCSPPTFHLAPN-----------------------------------------------------TFNVGCRESQLCNLG--LSEYPACARSNMAALQGYGGLADGSYGRLQTTGGAVASAQASESFLPQRTSSLIAAGMQGGAHGSLATGNSGSGSGGGKMDAYGSQLASFPASQLQYVMQAGASSASGSSASSGSSSSSAHMFSGSHHHVQQSTYNAFSLHNPYNLYGYN---------FPASPRLAASPEKP---QGGLLCSSSSAGAFAERQYLSNGGMDSMHMIGNPTGSQQGAGSCDGRQY----GSSSQMSMHMV---------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W198-1", "uniprot_id": "Q9W198_DROME", "id": "Q9W198-1", "name": "", "aln": "MTYELPPIILKGKELIKYRHIKRKYPVSKDFLHSNWWNVERFIVYALSPRCVIRNYAWRRRRTRSVCIIRRVRILLFDPRLKRMIKRRLQNVRHWSKGLVNYYKKMGRIEEHEETEVYRVAEPLAAEELSKQMKQQLELLKTGKRSLSLIEETTAIAEVPPKKPKQFPDITEEARVINDSDDRLDAAPSKQAAERTPTKSPAQVAASEDVPTPATPSKEQSGQTSTCSSAEKTDKVEKVGGGSKFLDMLISKVRVKNFARENNMPAEPSAVTFCTSEDEGSADFVGFDESVHQPGMLLTPLVPNNCKTTEGNSAFVSESLDAYMREHHINDSDSQDDKDKLLEPMGHDGQVTSHSMPPPMDMPAVPEALQRLRTVAERRQYLQRCKNHKMGIINNEANVYRELQRKQRQRKVKIGAMQALQASDSQMPFTRQGWQAASYVATEHSKYYYQVIQVDGEMVRLPGAQGNNLKREKSPYLSRLSRKEQEELKCSEQCLDARIQQELKVIPTRVSPPRNPKILNQYPLPAIFRPCPLSKKPLQRPLDDDTAALLLAGGSMAVVSMPNVELDVMPQLGRPLDEIAKRYLQHILPHHDITREWAEFSVSTLQAPPATMKDAEEQASQTPAGRRKSFTFVIPYLNDRNHILVRRVVDRSEHLDRSFKEEPNKLQEFTFREMLPPQPDAEIVACAEMISDMINTVAISCSENSFISEDPDALDASSVPKSSDLCPAKEETGKDTDKSGAKPKNLPNKQKRLANELRRLNATIIDAAARKADANKPCSKDYCHLGCICASLAGTELPVRDHCGRAECVLDCRCLSAEESRVMRLEAADGRGISNEDAFNLRRKATARLAKMEKDFTSTLVLTDNETLLINESQGDKKRRCTKAPKRYEDFDDSIYDEEEKDVVSPTTRKQKKHAAAAAAAAAAAAAAAAASAKISAPALSEPCFVKDTDLAKLKHCFVGLRRLSNVENLATFCMTHQLYKCFCGGDSPDGKPVVIEKDQWNAPVTHFNPDLAVRAHYSFERPPEETSTKKKGKEKKPKHKLESKSSNDVADQKPQTQAVETLPLKTESKQEPPPANSLFKDESPLKRSNELNKIFNYFRSRPDVCRRAISIPKNSYQRLNQRRADRVRHQIAREESLKTNEMLKMRIQGAVVYYRKEIDRQRKRELSKKPVIEVRNESDASDASVRQKKIETPAEGPTPGKRIKLKADEPPAQEKKAHMLDIQVPRIAACYSLNTASVDVLAPDMAKEATTSAAATGSTHGSTDTNSANVCTFYNDVVKNMNTLVSKKMQDIDLALQRESKIIPSPNEEILCIIKWTNFLAAFESGFVFIWDVQMKTHNFLAATTTNLMPSVCGAIAVVNTKFAPDPQALPLMARMLMNSMRNEKTNRLAVVMQGRQSFWLVKGFLRHMQGNACTKPTPMTHPLLTKKINVLCSLLVKQRVRENEKKTLGDGSGAPYEVLAGDVSPQTSLLMKNRSRDLKRKSQADERLLPSGPSMTKSSKPSAGGYPIAASVATSTTSAFASSSGKSTPVCTAKTNSASTKNKSSATGIRSNIEFRKVNHNDVDELQIPELHQTDHRWVVLDIFDDFSHIFVPSFSDMISLTRIHSVMQVAEERQKVVKLQFFPNAPYDAFVTPSSKKKIYFGPLSLDMPPPVLVLLQSVDRKMMLREVYQREHSIPVQRHRRSMAFWVLQINGQVHFEIDTESTAKLAAQQKNAIGTPPGLNVLKIPSQLSVEIEKNQDEVPPVVVIDSDEEDDDGERQLVIDEQDDEQAETDVKQEVERTGFTIQTLPSSGALQITISDSAETSSHPAKDVNTCHFSGGFMPFIANVPAKFGETAPTTQFLTPQVQVTTSQSGPETLTSSSSSHLPASKSAYPKIN-----ESLQELFSSGVPPGGITITKVDSQEKTLPNETVQVVKNKKSIAITGIHKQVTKAASSTATVTAARAPVVKPQSTSVSKVAPPIRPGATTQPKTLVRLYPKPALAAGRKSLPANAKTPVATPRQSQPVACDKPPLVSGSTLPALVEPSARKSLPSKPLAAGEHLRPRQSLPAKVTANPPAAARPDAASTSAQNLTNVSKAQLAKEEICYGIMVAKDLPRFRAKVEGSDFMIKIPEHGVFRFKTFGLAASFLSRHVAKDPKLKQFLPAEWKFHPLEQFNKQVPSRSQQSPAAIVIED", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :::. .* :: * * :. * .: * *:* . * . :*::.: . : .. : .*. : .. *..: ::.. . * : : * : ::: . :. :* * *: : : * .... *. *:*: . :* :. ::*::. * : . ::. . *.:*: . :: * : . :* : : :. .* * .: * .:::::**:: .*:. :: *: * :*. : :* * .:.. . * ... :*.:*: . *::.:*:: *. ..* .. :: :: .: *** :. : *. :.: ** .: **.* . ** . . . **.. : .: * . .:: : *::. : : . . :::. : : *. : :..*.:.:* ..: .. ... .: ..* ::* . .* * : .::**. . .: : :. .:.* * * . :* .. *. . : : . * . :: * .* . : . . . . *.: . .:::: : ", "identical_positions": 78, "similar_positions": 241, "identity": "3.58%" }, { "cls_id": "homologset.agr.MGI:1277238", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZXR2-1", "uniprot_id": "D3ZXR2_RAT", "id": "D3ZXR2-1", "name": "Cilia- and flagella-associated protein 44", "aln": "MKEPGDQDT-DGGRSGSRSEGKQSSRSTSKAA-----------EDITDDLFTDGAESFLDDDLDLEDMNESSHSSQE-YFHTPVVSQEPPPELKEEPE-EVKKKLSETFYYDYLELISTPYVSSPDRIPLYFLALNHSFGYDCKRRANLQLLDNNTLMYIAGNQMVLLDFKNKTQMYLQSSSGQGIGAIGVHPDKTY---FAVAEKGSFPKIIIYEYPSLKPYRILQDGTEKAYAYVDFNNEGNLLASVGCHPDYTITIWDWKGEQPILRTKAFSQDVFKVTFNPDNDEQLTTSGSGHIKFWEMAFTFTGLKLQGSLGRFGKTSTTDIEGYAELPDGKVLSGSEWGNLLLWEGSLIKVELCRTGMKSCHNGSINQIMLDEGEVITAGSDGSVRIWDFETIDTADVIDDSGLLEIEPINELHVDKSVNLFSMIKMN--EVGNNFWLAQDANGAIWKLDLSFSNITQDPECLFSFHSGAIAALDVSPLTYLMATTALDCSVRVYDFASKNLLVQMKFKQGGTTLIWAPLTVSISGSQIVVGFQDGVVRILELFDPKGLTVFAGRKKLLDAELHLKYVFKPHTEVVTALAYERDGEVLATGSDDKTVFFFDVEK------EYKPIGYFNTPGPIRQLMWSPHSHPESTLLIICGNGYILECLCPTIK-DVDDQNLVTFAIP-DMLVRCFHFSSVKSKILRYMEVQRREKQKELREKEREERKRKLMEEKEALGEQEIQEEEEEASEEEEEEEEEEPLPEIFTPPTPSPILCGFYSVPGKFWVSLGNYDSGFLYHCQFPPHLVKDDFQKLENEPFDFRILENTDDNPIRTITFSSNYTMMFCGMKNGAIRTYFLSENDPFLISLQDYWHFNVHDNNYGSVKSIFPSFDDQYLVTAGEDGNIFVFDIFSEFIIQKEAKAHVPSPRYGIEAEVAPEDIDDPKAYSIENARRKREHDKLMKKVEELKAQKRQQIKILRNEFWKLLALNKELPKHMQFHRTEFNIDAKIHAEIHKKTSIKIEQVEKELAWEKQKYELGLKKVQDRFREPLESDTVVVYAIQSDHQIASYRLVKPSKYSKLKRPSQTDRRPSKMERFEKEGPGKRESQRDTGGSLSLQEEVVLEKGKKARPRTLSEIMVENQIEKTRKLVQQAERAQLKILQRKREWEELYKSKPDDDYEDPRDVQAIKEAQTFMGDFNLKTASDYKIPEHMRINAAKKEEELGLLDTMAHGKKRYMNKCILSLRDLKLAVIEEIQCLVQELKTIQSSIPPAKHMTIPQVPQIYP-EEVPERRFQYDEETLLRFKRKQQKQRQDDKSSNSSKQSGSGASTGGGLGFLKLSSGKEGDLTTRDSLSRSSKAFAF-LELPKATEFEKAEPGDVELEIMKRD--------EVKHLYMQQFLCNR------IKELTVTFDAELHLLRHQKLKLDTQMKLSDLHHVTLFQEMLLLKNFEKQENILQERVNSLDREEQDMQWKINETLKEMEEKKNEINKLQEQEKSLYSGFQSALGENNKFANFLMKVLKKKIKRAKKKEVE-EADEDEESEESSEEESSLES-DEDESGSEDEVFDDSICPSNCDVSLFELALQLREKRLDIEEALVEEKKVVDNLKKEYDTISKKVKVVATNLNAAEEALEAYQREKQQRLNELLVVIPLKLHQIEYVVFGEVPEDLSGTLIFSNHSLDRLQERIVQLQEENAKQQKLNKECRERRKLLIREKREMAKTISKMDETVRELMISKFGRVIDLEALQTLSVNTTLEELKIKKLRKELSNAKEIRMWEEKIAQVRWDLMMKTKEHTKKLHQMNDLCLEKKRLDSRLNTLQNQQGNAFQGPRKADIVAKQKVTELVQTQSEKISALKEEIALLRKKG-----------------------------GLILPPITPMQENEMRHMDA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q5M6-1", "uniprot_id": "CFA44_MOUSE", "id": "E9Q5M6-1", "name": "Cilia- and flagella-associated protein 44", "aln": "MKEPDDQDTSDGGRSGSRNEGKLAHKSILKSS-----------QDTTADSYTDGEESYLGDDLDLDDMDESSHSSQE-YVQAPAPSQEPPVEVKEEPEADVKKVLSETFYYDYPELVSIPYVSSEERIPLYFLTLNHSFGYDCRKRANLQLLDSNTLLYVAGNQMVLLDFKDKTQIYLQSSSGQGIGAIGVHPKKTY---FAVAEKGSFPKIIIYEYPSLKPYRILRDGAEKAYAYVDFNNEGNLLASVGCHPDYTITIWGWKEEQPILRTKAFSQDVFKVTFNPDNDEQLTTSGSGHIKFWEMAFTFTGLKLQGSLGRFGKTSTSDIEGYAELPDGKVLSGSEWGNLLLWEGSLIKVELCRTGMKSCHSGSINQIMLDEGEVITAGSDGSVRIWDFETIDTADVIDDTGLLEIEPINELHIDKSVNLFSMIKMN--EVGNNFWLAQDANGAIWKLDLSFSNITQDPECLFSFHSGPIAALAVSPLTYLMATTAMDCSVRVYDFSSKNPLVHMKFKQGGTSLIWAPRSVSVSASQIVVGFQDGVVRVLELFDPKGLTVYAGRKKIPDAELHLKYVFKPHTDEVTALAYERDGDILATGSEDKTVFFFDVEK------EYKPIGFFNTPGPICQLMWSPASHPEKTLLIICENGYILESLCPTIK-DVDDQNVITFAIP-NVFLRCFHFTSVKSKILRFLEVQRREQQKMLKEKEKLERRMKLAEEREAFGEEEIPEEE----TSEEGEEEEPPLPEIFMPPTPSPILCGFYSEPGKFWVSLGNYDAGFLYHCQFPSYLHNSDFQKQENEPFDFRVLENTEDNPIRNITFSNDQTMMFCGMTNGAIRVYVLSENDPFLVSLQHYWHFNVHDNNYGSIKSITSSFDDQYLLTAGEDGNIFVFDIFSEFIVPKGIKAKVPSPRFGIESEAAPEDIEDPKAYSIENARKKREHDKLMKKVEELKAHKREQIKILRNEFWKLLELNKELPAHMQFQRTDFNIDAKIHAEIHKKTSLKIEQVEKELAWEKQKHELGLKKLQDRFREPLESDTIVVYATQSDHQIASYRLVKPSKYSKLKRPSQSERRQSKMERLEKEGPGKKESQRDTGGSISLQEESVLEKGKKFRPRTLSEIMVENQIEKTKKLIQQAERAQFKILQRKKEWEELYKSKPDDDYEDPKDVQAIKEAQTYMGDFNLKTAPDYKIPEHMRINAAKKEEELGYLDTMAHGKKRYMNKCILSLRDLKLAVIEEIQCLVQELKNIQSSIPASKHMPIPQVPQIYP-EEVPERRFQYDEETLLRFQRKQ-KKRQDKSSSKQSGTGSGGSAGGGLVGFLKLSSGKEGDLTTRDSLSRSSKASAL-LELPKPVEFEKAEPSDAELEIMKRD--------EVKHLYMQQFLCNR------INELTVTFDAELHLLRHQKLKLDTKMKLSDLHHLTLFQEMLLLKNFEKQENILQERVNSLDKEEQDMQWKINETLKEMEEKKNEITKLQDQEKALYAGFQAALGENNKFANFLMKVLKKKIKRAKKKEVEGDADEDEESEESSEEESSLES-DEDASGSEDDVFDDSICPTNCDVSLFELALQLREKRLDIEEALVEEKKIVDNLKKEYDTISKKVKVVATNLNAAEEALEAYQREKQQRLNELLVVIPLKLHQIEYMEFGEVPEDLSGTLVFSNHSLDRLQERIVQLQEENAKQQKLNKECRERRKLLIREKREMAKTISKMEETVRELMISKFGRVIDLEALQTLSVNTTLEELKIKKLRKELSNAKELRMWEEKIAQVRWDLMMKTKEHTKKLHQMNDLCLEKKKLDSRLNTLQNQQGNAFQGLRKADIVAKQKVTELVQTQLEKITALKEEIELLRKKG-----------------------------GLLLPPITPKPKNEMKPMDT--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96MT7-2", "uniprot_id": "CFA44_HUMAN", "id": "Q96MT7-2", "name": "Cilia- and flagella-associated protein 44", "aln": "MKEPDDQDTDGEKSVTSKSDGKKSLRSSKSESRSPVQEDNTFLEDDTDETFTKGEGSYLEEDSDEERLEGSLSSFQYGDLQSTTVPQQTPAPAVEEAEEEVKKKISESFFYDYMELASMPFVTLDSNIPLDLLTLVHSFGYDCRKRANLQLLDDSIAIYIAGNQLIFLNLKTKEQIYLRSSSGEGIGVIGVHPHKTY---FTVAEKGSFPDIIIYEYPSLRPYRVLRDGTEKGYAYVDFNYSGNLLASVGSNPDYTLTIWNWKEEQPILRTKAFSQEVFKVTFNPDKEEQLTTSGSGHIKFWEMAFTFTGLKLQGSLGRFGKTITTDIEGYMELPDGKVLSGSEWGNMLLWEGGLIKVELCRGTSKSCHNGPINQIMLYEGEVITVGSDGYVRIWDFETIDTADVIDETGLLEIEPINELQVDKNVNLFSMIKMN--ETGNNFWLAQDANGAIWKLDLSFSNITQDPECLFSFHSGAIEAVAVSPLTYLMATTALDCSVRIYDFASKTPLAQMKFKQGGTALVWVPRMVNFTGAQIIVGFEDGVVRILELYDPKGLTIFAGRKKILDADIQLKQVFKPHTACVTALAYERDGEILATGSKDQTVFFFEVER------DYKPIGYINTPGPVCQLMWSPMSHPESTLLIICENGYILEAPLPTIKQEEDDHDVVSYEIK-DMCIKCFHFSSVKSKILRLIEIEKRERQRELKEKIREERRNKLAAEMGEDGEKEFQEEEE---EKEEEEEEEEPLPEIFIPSTPSPILCGFYSEPGKFWVSLGGYDSGFLYHCEFPPCDESSDFKEQKDEPIDVRYLADTEDNPIQTITFNINKVMMFCGMKNGAIRVYVLNQNDPSLTSLVDYWHFNMHDNNYGCIKSIANSFDDRFLVTAGADGNIFVFNIFSEFMLRKDMKAKVPSPRFGIETEPIPEDIEDPKAYSIENARRKREHDKLMKEVGEIKARKREQIKALRSEFCNLLEMNEKLPKHMQFKRTDFDVDSQIRAEMHRKTAFKIQQVEKELAWEKEKHELGLMKLKNRFRDPLESDTIVVHAILSDHKISSYRLVQPSKYSKFKRASQSERKPSKLDRFEKEGPGRKDSQRDAGGSVTIQEESIIEKGKKFRPKTLSEIIVENQIEKTRKLILKAERAQLKIQQRKKEWEELYKSKPGDDYEDPKDLQAIKEAQVYMGDFNLKTAPDYKIPEHMRINAAKKEEELGHLDSLVHGNKRHMNKCILSLRDLKVAVVEEIQCLVQELKNIQSTLHISKHIPIPKIPQIHP-EEVPEKRFQYDEETLLNFKQQQ-MKSKDEKSPGVEQTGSGGPVG----GFLKLSSRKDGDLTTRDSISRSSKASTFSLDIPKCLEFEKAEPTDVELEIMKRD--------EIKHVYMQQYLVNR------IKELVVTFDAELRLLRHQKLKLDTQMKLSDLHHVTLFQEILLLKNFEKQENILQERVNSLDKEEQYMQWKINETLKEMEEKKNEITKLQEQEKALYAGFQAAIGENNKFANFLMKVLKKKIKRVKKKEVEGDADEDEESEESSEEESSLES-DEDESESEDEVFDDSICPTNCDVALFELALHLREKRLDIEEALVEEKKIVDNLKKEYDTLSKKVKIVATNLNAAEEALEAYQREKQQRLNELLVVIPLKLHQIEYVVFGEIPSDLSGTLVFSNHALRRLQERIHELQEENSKQQKLNKEWRERRKQLIREKREMTKTIHKMEETVRQLMISKFGRVVNLEALQTLSVNTTLEELKIRKLRKELANAKEMKMWEEKIAQMRWELMMKTKEHTRKLYQMNDLCIEKKKLDSRLNTLQNQQGNAFQGPREADVVAREEVTELIQLQAERISALKEEIALLRRKG-----------------------------SLILPPIQSPREKEIQPADL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q0E8T7-1", "uniprot_id": "Q0E8T7_DROME", "id": "Q0E8T7-1", "name": "Cilia- and flagella-associated protein 44", "aln": "-------------------------------------------MDTTQESDLLGEEEELENENDVS-------------------------------------------------------------FPRDIVSVEHSFGYDCKKLFNLVLVDSDTLVFASGNFLNYFSISRQEISFQETVYGCGVGFITKNEHPDYTNLFTVGENGARPTVFIYEYPSLNVRVKLLNAAQNCFTAGSYNKTGELFASQAGYPDFIITIWRWENAEVVLRAKSFQSDILFVHFSEHNPILLCSSGLSHIKFWKMANTFTGLKLKGDLGRFGKTDFSDIYAMYMLQDENVISGSDWGNMLLWQAGLIKFEICRKGRKPCHTKPITRITMKNGEVTTVGMDGYVRVWYWETVDLADPPEDDLFVEIDPIYEFKIAD-VELRCMQKIHPFDESDFTHYAQDGNGGIWFCDINTYDVPQKPRKLYSCIGGKVLAAQMSPVSPHFLCMSESGKLFVYQYDEQRLILEKEFPAEGVDVIWLDTNISVKGTELVAAFKDGILRQMYLDLSNGE----------RPKMTRVRAFKAHTSPITALTVSRNSSLLLTGSADKSIFIYQLSRDEHQMVDMRPLGFVQFAAIPNCFYWHETEP--TVVLVGCKSGDLYEYNIRTEV--TDHETYLSYNITENSRMRHTKFASIKSRIRRDIHRENVKKRKERKRERKMNEVEKLKKANPGLQIDIESALAD----SEPDEEEEP----LHIPTVPNAIIWLRYTLRDTIWVSMAGYDAGYIYELEFN-----------AAEPTRATIIAEADD--IEIHSYCIIDEFIIFGLHNGRIRINRINPDN--FTDLSEFRIYPMHDGLKGTIPKIDISYSGEHLLTIGYDGNVFLHKWNGPKIVRNKVRDKLPPLPEGVTQIPD----IEPEACSLEQEKINAELRRQQEAADAHDRDVLSKIGALQNVYFDIIRINEELPPGLRAKDTDLLLDDRITRQIRNELQAELDDVREDLAYDLEFAQVGHTKLYNHFLKELVQVPFTVAPLRANVPGVSTFRLQALGEEHAQIKQDIEDRLKREHDMGLHDYVAPERSDESIGEPPPESFFFGRDPKSIEPRFS---------KKMMRLLTRYRKRQIFEVRRIFDWDKLERQKPDPNRNHPDDDAQIEDAKRNLGDFKLKIGSDYEPKSSE--TLTQKYIEVVECREQYFAMVDAFNQMVLDLRERKGELDQFITAKRNRLAVIHNYLPEPDRQPLDPIQEIDMDLEYPELNLIEHYTPGCGVEIDDILTLEHSVDQVIARMAPMRSTANVSLFSLHGLDVPELHEHTAFTMLQISKLNRSLPNAELDEELLKLPPKSDPAYFELNDDGQVPYMMETRHRWLRQLLVEQNAIRTEVDEEVRQFDKALEKLQVRRFHVKMDAEFMTAFMNSLNQELYILRDSEEIETQLLLNAKTAMSTRNDLQMVINSTNRQLDELRRNIDKLGEQIVALQVLFATTVKG-HKFFDFLRRIFKKKWRPPKVSRGDDESSSSSSSSSSSSEDEQADNKSLDSLDMTTIRLDEATCPTGLDRSLYDLAFSMRSDRHDLERNVRELTREVENKRKEIAEMQIKMKFHEEVYQREKNALLQFRRNRQQEVNKVHISAILRMDQLQHFYDGDDYRDLSKAILFDADMLVDLRRRADQLSEETLATKRWHRINFIHLRRMNTDIKFMRFEITRLEEEIRQAMMKKFGIIVNLDELEEEVLRRYIFDLETNAEDELMALEKELLEKQKELARCEEELVLETQNNTEKVNIMTVLREENNILRTLLDIQNKNYAKWANPNALNLSYDIEKLRGIEKSLLDQIECLEREICALRLKSKPLQINYEFEVDPNAQPQVVTSEIMPNDDAMVCPAILNVDAYMLPPMPDEFIMDRVQTIVQKSFNRFFGKSTTPENVRKFAQRSSLYLCQAAYSFQGRYTDRIAECITEHLQTFVPKKYFIHISNEELRKLFNEVVAVFDYERSDVNTEELISGIFDHAKDSLCAHVHMGDSEVVNRTHFIVAHMFKELIEVLPLEEFQADETLRMIVDVLEREPMVDPRAIAVEQLIDSTLQHARENLIDGITAVPIRSLGSSIQRDLIKRRQYKQPSCESPMSVRIATKKPGTSSGLPF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * : * . * :: * . :* :::: *******:: ** *:*.. :: :** : :.:. : : .: * *:* * : . * *:*.*:*: * ::*******. * :.::: :: .:* *:*:** . **: :*** *: : :**:*:*..::: * *. .: * :** .*****:** *******:*.******* :** . * * :*:***:***:***:..***.*:** *.**. .*.:* : :*** *.* ** **:* :**:* ** :: ::**:** *::: . *:* .* *:: : .: ***.**.** *:. ::.*.*. *:* .* : * :**:: : : . .: :*:: .: : . :* *. ::* :....::::..*:**::* : * .:* ..: .**.** :***: .*:..:* *** *:::*::::.: : :*:*:.: .. : * . ..:*: * .* : * * *.. ::: * : :: :*:*:**:* * :. :. :::: :.: : :. ** . .* **** :. *..*..*: *: ..:***:..**:*::*. :* ** : :::* *. :: ::: *: ** ** :. :: : .* .: : :**. * : .* *:....*:* * ***:*:.. . :: : : ::*. *: :*:* *:*: : : * : : . . .:* *:. : .:: :*::** :: : *:: :* :* :::.: ::::*.::**:: : ::* *: ::* . * . ...* . :: * ::. .: : .: : : .: . : .. : . :: *. . :. . .. *. .*: :* :*: : .: *: :* :*::* :.**. : :.* * *::*: :***:** ..**: . . ::* *: .. :*: :*.**: * : : * . :.* *:. : ..: .: : :* * ** .: . . .: .: :.. . . . *: . : . * :: : ** : *: * * . : .* * :* :::* * :: :.* . ** *. *: :::::. . :: . :* **: :*:: *: *. * ..:: .: :* **.* ::::* :.:* ** :* :* * ::: :** :** :::*** : * .. : ::.....*..**.*:.. :. . * :*:: **:. * :*::**: :*..* *:*. : * .: *:* :** :. *:*. : ::** ::*::**.:*:: : *::.*:::. *: *** :::*. . * *:.* :*.**. :: :: : : : : : * * :::* :*: *:.*** :::*: *: :. : :*: . : :: **: ::::*: . :*:::*:::*.*: *. * *:: * : *: ::: .: : ::: : : ::* .*:.** ** *. .:: *.* : ", "identical_positions": 402, "similar_positions": 645, "identity": "18.6%" }, { "cls_id": "homologset.agr.MGI:1277241", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A2AJB7-1", "uniprot_id": "LCN5_MOUSE", "id": "A2AJB7-1", "name": "Epididymal-specific lipocalin-5", "aln": "MCSVARHMESIMLFTLLGLCVGLAAGTEAAVVKDFDVNKFLGFWYEIALASKMGAYGLAHKEEKMGAMVVELKENLLALTTTYYNEGHCVLEKVAATQVDGSAKYKVTRISGEKEVVVVATDYMTYTVIDITSLVAGAVHRAMKLYSRSLDNNGEALNNFQKIALKHGFSETDIHILKHDLTCVNALQSGQI---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P06911-1", "uniprot_id": "LCN5_RAT", "id": "P06911-1", "name": "Epididymal-specific lipocalin-5", "aln": "-------MENIMPFALLGLCVGLAAGTEGAVVKDFDISKFLGFWYEIAFASKMGTPGLAHKEEKMGAMVVELKENLLALTTTYYSEDHCVLEKVTATEGDGPAKFQVTRLSGKKEVVVEATDYLTYAIIDITSLVAGAVHRTMKLYSRSLDDNGEALYNFRKITSDHGFSETDLYILKHDLTCVKVLQSAAESRP", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **.** *:*************.*******:.**********:*****: ****************************.*.*******:**: **.**::***:**:***** ****:**::*************:*********:***** **:**: .*******::*********:.***. ", "identical_positions": 148, "similar_positions": 29, "identity": "75.9%" }, { "cls_id": "homologset.agr.MGI:1277947", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JIX3-1", "uniprot_id": "FHIT_RAT", "id": "Q9JIX3-1", "name": "Bis(5'-adenosyl)-triphosphatase", "aln": "--MSFKFGQHLIKPSVVFLKTELSFALVNRKPVVPGHVLMCPLR-PVERFRDLRPDEVADLFQVTQRVGTVVEKHFQGTSITFSMQDGPEAGQTVKHVHVHILPRKSGDFRRNDNIYDELQKHDREE-------------------------------------------EDSPAFWRSEEEMAAEAEVLRAYFQA------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O89106-1", "uniprot_id": "FHIT_MOUSE", "id": "O89106-1", "name": "Bis(5'-adenosyl)-triphosphatase", "aln": "--MSFRFGQHLIKPSVVFLKTELSFALVNRKPVVPGHVLVCPLR-PVERFRDLHPDEVADLFQVTQRVGTVVEKHFQGTSITFSMQDGPEAGQTVKHVHVHVLPRKAGDFPRNDNIYDELQKHDREE-------------------------------------------EDSPAFWRSEKEMAAEAEALRVYFQA------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49789-1", "uniprot_id": "FHIT_HUMAN", "id": "P49789-1", "name": "Bis(5'-adenosyl)-triphosphatase", "aln": "--MSFRFGQHLIKPSVVFLKTELSFALVNRKPVVPGHVLVCPLR-PVERFHDLRPDEVADLFQTTQRVGTVVEKHFHGTSLTFSMQDGPEAGQTVKHVHVHVLPRKAGDFHRNDSIYEELQKHDKE---------------------------------------------DFPASWRSEEEMAAEAAALRVYFQ-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P49775-1", "uniprot_id": "HNT2_YEAST", "id": "P49775-1", "name": "Bis(5'-adenosyl)-triphosphatase", "aln": "MNKPIYFSKFLVT-EQVFYKSKYTYALVNLKPIVPGHVLIVPLRTTVLNLSDLTMPESQDYFKTLQLIHRFIKWQYKADSINVAIQDGPEAGQSVPHLHTHIIPRYKINN-VGDLIYDKLDHWDGNGTLTDWQGRRDEYLGVGGRQARKNNSTSATVDGDELSQGPNVLKPDSQRKVRALTEMKKEAEDLQARLEEFVSSDPGLTQWL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: *.:.*:. . ** *:: ::**** **:******: *** .* .: ** * * *:. * : .:: :::. *:..::********:* *:*.*::** : .* **::*:: * : * *: ** ** *:. :: ", "identical_positions": 54, "similar_positions": 49, "identity": "25.96%" }, { "cls_id": "homologset.agr.MGI:1277950", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JHK1-1", "uniprot_id": "Q9JHK1_RAT", "id": "Q9JHK1-1", "name": "Caspase-9", "aln": "MEEADRQLLRRCRVRLVRELQVAELWDALLSRELFTRDMIEDIQRAGSGSRRDQARQLVIDLETRGRQALPRFISCLEDTGQGSLASFLQSSGQAAKQDPEAVTPLDHLVPVVLGPMGLKSKEQKVVKLDPSQPALGNLTPVVLGPEELWPTRLRPEVLTPETPRPVDIGSGRAHDVCTPGKIERHADMAYTLDSDPCGHCLIINNVNFCPSSGLSTRIGSHVDCEKLQHRFCWLRFMVEVKNDLTAKKMVTALMEMAHRDHRALDCFVVVILSHGCQASHLQFPGAVYGTDGCSVSIERIVNIFNGTGCPSLGGKPKLFFIQACGGEQKDHGFEVAFTSSQDKAFDSDSEPDAVPYQEGPRTL----DQLDAVSSLPTPSDILVSYSTFPGFVSWRDKKSGSWYIETLDGVLEQWARSEDLQSLLLRVANAVS---EKGVYKQIPGCFNFLRKKLFFKTS--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C3Q9-1", "uniprot_id": "CASP9_MOUSE", "id": "Q8C3Q9-1", "name": "Caspase-9", "aln": "MDEADRQLLRRCRVRLVSELQVAELWDALLSRELFTRDMIEDIQQAGSGSRRDQARQLVTDLETRGRQALPLFISCLEDTGQGTLASLLQSGRQAAKQDPEAVKPLDHLVPVVLGPMGLTAKEQRVVKLDPSQPAVGNLTPVVLGPEELWPARLKPEVLRPETPRPVDIGSGGAHDVCVPGKIRGHADMAYTLDSDPCGHCLIINNVNFCPSSGLGTRTGSNLDRDKLEHRFRWLRFMVEVKNDLTAKKMVTALMEMAHRNHRALDCFVVVILSHGCQASHLQFPGAVYGTDGCSVSIEKIVNIFNGSGCPSLGGKPKLFFIQACGGEQKDHGFEVACTSSQGRTLDSDSEPDAVPYQEGPRPL----DQLDAVSSLPTPSDILVSYSTFPGFVSWRDKKSGSWYIETLDGILEQWARSEDLQSLLLRVANAVS---AKGTYKQIPGCFNFLRKKLFFKTS--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P55211-1", "uniprot_id": "CASP9_HUMAN", "id": "P55211-1", "name": "Caspase-9", "aln": "MDEADRRLLRRCRLRLVEELQVDQLWDALLSRELFRPHMIEDIQRAGSGSRRDQARQLIIDLETRGSQALPLFISCLEDTGQDMLASFLRTNRQAAK---------------------------------LSKPTLENLTPVVLRP-EIR----KPEVLRPETPRPVDIGSGGFGDVGALESLRGNADLAYILSMEPCGHCLIINNVNFCRESGLRTRTGSNIDCEKLRRRFSSLHFMVEVKGDLTAKKMVLALLELAQQDHGALDCCVVVILSHGCQASHLQFPGAVYGTDGCPVSVEKIVNIFNGTSCPSLGGKPKLFFIQACGGEQKDHGFEVASTSPEDESPGSNPEPDATPFQEGLRTF----DQLDAISSLPTPSDIFVSYSTFPGFVSWRDPKSGSWYVETLDDIFEQWAHSEDLQSLLLRVANAVS---VKGIYKQMPGCFNFLRKKLFFKTS--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QSB1-1", "uniprot_id": "F1QSB1_DANRE", "id": "F1QSB1-1", "name": "Caspase-9", "aln": "MEQKHRQILQRHRLNLVKALNPEDVCDKLLSKGVFTQDMIDEIQSKAT--RRDQARQLVKDLETRGSLAFPAFLDSLRETGHNDLAELLQSGDGVHRPPVISVQP------------------------SPIPLPVQNLN-HTEKPDKPDIASPRLVPLRPESLPVHKTYSPPSETVVRPTRPRRDSIQCYKMDASPCGVCLIINNINFEKASELNDRKGSNIDCDKLEKRFKALNFEVTVKRNLKSKRIRHEMASLAKKDHSTYDCCVVIILSHGTEASHNRFPGAVHGVDGPAVPIQIITNYLNGQNCPSLQGKPKLFFIQACGGGEKDIGFEVSPDDVQPSIGGIDDEMDAIPMSSSSDSLSTASDELDARASLPTPSDILVSYSTFPGYVSWRDTEAGSWYVENLDRVLEENAITDDLVTMLMLVNDAVSQISAKGLYKQMPGSFNFLRKLLYFQSSQS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:: .*::*:* *:.** *: :: * ***: :* .**::** .: ********: ****** *:* *:..*.:**:. **.:*::. . : .: **. . * : : * **: . * * . .: .* :. .*** ******:** * * * **::* :**.:** *.* * ** :*.:*:: : .:*:::* : ** **:***** :*** :*****:*.** .*.:: *.* :** .**** ************* :** ****: . : . : * ** * ... .: *:*** :********:********:***** ::****:*.** ::*: * ::** ::*: * :*** ** ***:**.****** *:*::* ", "identical_positions": 188, "similar_positions": 113, "identity": "40.6%" }, { "cls_id": "homologset.agr.MGI:1277953", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZTJ0-1", "uniprot_id": "D3ZTJ0_RAT", "id": "D3ZTJ0-1", "name": "Protein XRP2", "aln": "MGCCFSK--RRKSGKE--SRTEGEE---------------------EQPKLYSWDQREKVDPKDYTFSGLKDETVGRLPGKVAGQQFVIQDCENCNIYIFDHSATITIDDCTNCVIFLGPVKGSVFFRNCRDCKCTLACQQFRVRDCRKLEVFLCCATQPIIESSTNIKFGCFQWYYPELAAQFKDAGLSIFNNIWSHVHDFTPVSGELNWSLLPENAVVQDYVPLPTTE-EFKAVRISTDPNRSIVPVSRGQRQKYSDESCLVVLFADDYTTANARKLIDEMVGKGFSLVQTKEMSMKTEDAQRVFREKASDFLLLLNKGPVIALEFNGDDAVQECHLIVNGLFNGTKMFVSEKKETASGDVDSFYNFAEIQMGI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EPK2-1", "uniprot_id": "XRP2_MOUSE", "id": "Q9EPK2-1", "name": "Protein XRP2", "aln": "MGCCFTK--RRKSEK-----AEGEE---------------------EQPKLYSWDQREKVDPKDYMFSGLKDETVGRLPGKVAGQQFVIQDCENCNIYIFDHSATITIDDCTNCVIFLGPVKGSVFFRNCRDCKCTLACQQFRVRDCRKLEVFLCCATQPIIESSTNIKFGCFQWYYPELAAQFKDAGLSIFNNIWSHVHDFTPVSGELNWSLLPENAVVQDYVPIPMTE-EFKAVRISTEANRSIVPVSRGQRQKYSDESCLVVLFADDYTTANARKLIDEMVGKGFSLVQTKEMSMKTEDAQRVFQEKASDFLLLLNKGPVIALEFNGDDAVQECHLIVNGMFNGTKMFVSEKKETASGDVDSFYNFAEIQMGI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75695-1", "uniprot_id": "XRP2_HUMAN", "id": "O75695-1", "name": "Protein XRP2", "aln": "MGCFFSK--RRKADKE--SRPENEE---------------------ERPKQYSWDQREKVDPKDYMFSGLKDETVGRLPGTVAGQQFLIQDCENCNIYIFDHSATVTIDDCTNCIIFLGPVKGSVFFRNCRDCKCTLACQQFRVRDCRKLEVFLCCATQPIIESSSNIKFGCFQWYYPELAFQFKDAGLSIFNNTWSNIHDFTPVSGELNWSLLPEDAVVQDYVPIPTTE-ELKAVRVSTEANRSIVPISRGQRQKSSDESCLVVLFAGDYTIANARKLIDEMVGKGFFLVQTKEVSMKAEDAQRVFREKAPDFLPLLNKGPVIALEFNGDGAVEVCQLIVNEIFNGTKMFVSESKETASGDVDSFYNFADIQMGI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QC45-1", "uniprot_id": "XRP2_DANRE", "id": "F1QC45-1", "name": "Protein XRP2", "aln": "MGCFFSKKSRRKSPKKDAALPTGDESATGNDLAETNNTALGSNSNQEAPKQYSWDKREKVDPKDFMLTGLKNETVGRLPGKLNGQQFVIQDCENCNIFVLDHSATITIDDCVNCRIVLGPVKGSVFFRDCKDIKCVVACQQFRTRDCKKMDVFLCCATQPIIESSTGMKFGCFQYYYPELAFHFKDAGLSIFNNNWSNIHDFTPVSGETNWSLLPEDAVVLDHVPLPDPESEFKSVRIATEAGRSIVPLTKGSRRTESEESCLFVFFAGDYTTANARKLIDEATAKGFVLIQTKEVSMRPEDVSRVFQNNAESLTEWITKGPVVALELNGDGVVEACRSFANEVFNGTQLFVSESKNTSSRDVDNFFNFADMQMGL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** *:* ***: * . .:* * ** ****:********: ::***:********.: ****:*********:::*****:*****.** *.***********:*:* **.:******.***:*::**************:.:******:****** :*********** **::********* *******:*** *:**:* .* *:*:**::*:..*****:::*.*:. *:****.*:**.*** ********* ..*** *:****:**:.**..***:::* .: :.****:***:***..*: *: :.* :****::****.*:*:* ***.*:***::***:", "identical_positions": 232, "similar_positions": 89, "identity": "61.7%" }, { "cls_id": "homologset.agr.MGI:1277954", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VHK6-1", "uniprot_id": "I13R2_RAT", "id": "Q8VHK6-1", "name": "Interleukin-13 receptor subunit alpha-2", "aln": "---MALMAVNTRCLCLFLLCTITGHS----LEIKVNPPQDFEILDPGLLGYLYLQWKPPVVMDNFKECKLEYELKYRNVDSDSWKTIITRNLIYKDGFDLNKGIEGKIRTHLSEHCTNGSEVQSPWTEASYGIADEGSLGTKIQDMKCIYYNWQYLVCSWKPGKTVHSDTNYTMFFWYEGLDHALQCADYLQDNEKNVGCKLSNLDSSDYKDFFIRVNGSSKLEPIRSSYMVFQLQNIVKPLPPEFLHISVENSIDIRMKWSTPGGPIPPSCYTYEIVVR--------EDDISWESATDKNDMKLKRRANESEDLCFFVRCKINIYCADDGIWSEWSEEECWEG-YTGPDSKIVFIVPVC--LFFIFLLLLLCLIVEKEDPEPTLSLHVDLNKEMYAYEETLC----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88786-1", "uniprot_id": "I13R2_MOUSE", "id": "O88786-1", "name": "Interleukin-13 receptor subunit alpha-2", "aln": "-----MAFVHIRCLCFILLCTITGYS----LEIKVNPPQDFEILDPGLLGYLYLQWKPPVVIEKFKGCTLEYELKYRNVDSDSWKTIITRNLIYKDGFDLNKGIEGKIRTHLSEHCTNGSEVQSPWIEASYGISDEGSLETKIQDMKCIYYNWQYLVCSWKPGKTVYSDTNYTMFFWYEGLDHALQCADYLQHDEKNVGCKLSNLDSSDYKDFFICVNGSSKLEPIRSSYTVFQLQNIVKPLPPEFLHISVENSIDIRMKWSTPGGPIPPRCYTYEIVIR--------EDDISWESATDKNDMKLKRRANESEDLCFFVRCKVNIYCADDGIWSEWSEEECWEG-YTGPDSKIIFIVPVC--LFFIFLLLLLCLIVEKEEPEPTLSLHVDLNKEVCAYEDTLC----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14627-1", "uniprot_id": "I13R2_HUMAN", "id": "Q14627-1", "name": "Interleukin-13 receptor subunit alpha-2", "aln": "---MAFVCLAIGCLYTFLISTTFGCTSSSDTEIKVNPPQDFEIVDPGYLGYLYLQWQPPLSLDHFKECTVEYELKYRNIGSETWKTIITKNLHYKDGFDLNKGIEAKIHTLLPWQCTNGSEVQSSWAETTYWISPQGIPETKVQDMDCVYYNWQYLLCSWKPGIGVLLDTNYNLFYWYEGLDHALQCVDYIKADGQNIGCRFPYLEASDYKDFYICVNGSSENKPIRSSYFTFQLQNIVKPLPPVYLTFTRESSCEIKLKWSIPLGPIPARCFDYEIEIR--------EDDTTLVTATVENETYTLKTTNETRQLCFVVRSKVNIYCSDDGIWSEWSDKQCWEGEDLSKKTLLRFWLPFG--FILILVIFVTGLLLRKPNTYPKMIPEFFCDT--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7UYQ0-1", "uniprot_id": "A0A8N7UYQ0_DANRE", "id": "A0A8N7UYQ0-1", "name": "", "aln": "MLLLNRFSVWLSAFAVLLLTQPISTSEVMACGAAVDPPANIEITDPGFLGYLNIQWTRPASLQNLTGCTVRYQLRYFDTYEERWRSVRTVKLTYAAQFDLEKPVKLRILTVLKCACTNGTEVQGEETETVYTPEPTGLAGSRIRDFHCIYYGKEHMECTWKSGPVQPPNSEHYLYYWHREMEETKECPEYIVSSNNERGCRFPRQSLLEFSKFNMCVNGSSSTGSLRPAYFSIEIQNYVKPAAVSSLDV-LETDGRLKLEWAPPSGQVPEHCLDYEVESSTLMANGKELKQTEILENLDLGTSYELPREAESKKTCFNLRSKVNMYCADGGFWSDWSQTKCTVKPTLNYRLLDLVMIGTAGVIIFCLSLWILTRICIKPCSKKDVIYTLYKQKVNENMPSIFSPIFK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .: :*: . : *:** ::** *** **** :** * ::::. *.:.*:*:* : .: *::: * :* * ***:* :: :* * * ****:***. *: * * ::::*:.*:**. ::: *:**.* :::: :::*:. ::.: :* :*: . :: **::. . ::..* : *****. .:*.:* :::** *** . * . *.. ::::*: * * :* * **: .: . *:.. ** :*.*:*:**:*.*:**:**: :* . . : ::: : : : : * . : . :. ", "identical_positions": 92, "similar_positions": 126, "identity": "22.6%" }, { "cls_id": "homologset.agr.MGI:1277955", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88778-1", "uniprot_id": "BSN_RAT", "id": "O88778-1", "name": "Protein bassoon", "aln": "MGNEASLEGGAGEGPLPPGGSGLGPGPG----AGKPPSALAGGGQLPVAGAAR-AAGPPTPGLGLVPGPGPGPGPGSVSRRLDPKEPLGSQRATSPTPKQASATAPGRESPRETRAQGLSGQEAEGPRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTSS-QPNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTAPRSKSQQQLHSPALS--PAHSPAKQPLGKPEQERS---RSPGATQSGPRQAEAARATSVPGPTQATAPPEVGRVSPQ--PPLSTKPSTAEPRPPAGEAQGKSATTVPSGLGAAEQT--QGGLTGKLFGLGASLLTQASTLMSVQPEADTQGQPSPSKGPPKIVFSDASKEAGPRPPGSGPGPGPTPGAKTEPGPRTGPGSGPGALAKTGGTPSPKHGRADHQAASKAAAKPKTMPKERA-ACPLCQAELNVGS-RGPANYNTCTACKLRVCTLCGFNPTPHLVEKTEWLCLNCQTKRLLEGSLGEPAPLPLPTPQEPPAGVPQRAAGASPLKQKGPQGPGQPSGSLPPKASPQAAKASPQAAKAS--------------PQAKPLRASEPSKTSSSAPEKKTGIPVKAEPVPKPPPETAVPPGTPKAKSGVKRTDPATPVVKPVPEAPKSGEAEEPVPKPYSQDLSRSPQSLSDTGYSSDGVSSSQSEITGVVQQEVEQLDSAGVTGPR-PPSPSELHKVGSSMRPSLEAQAVAPSGEWSKPP--SGSAVEDQKRRPHSLSIMP-EAFDSDEELGDILEED-DSLAMGRQREQQDTAESSDDFGSQLRHDYVEDSSEGGLSPLPPQPPAR-ADMTDEEFMRRQILEMSAEEDNLEEDDTAVSGRGLAKHGAQKASARPRPESSQESVALPKRRLPHNATTGYEELLSEE-GPAEPTD--GALQGGLRRFKTIGLNSTGRLWSTSLDLGQGSDPNLDREPELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDSSPSRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQQRIRSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYSPSPSLDSEAETLDGGPTRLYKSGSEYNLPAFMSLCSPTETPSGSSTTPSSGRPLKSAEEAYEDMMRKAELLQRQQGQAAGARGPHGGPSQPTGPRSQGSFEYQDTLDHDYGGRASQPAADGTPAGLGATVYEEILQTSQSIARMRQASSRDLAFTEDKKKEKQFLNAESAYMDPMKQNGGPLTPGTSPTQLAAPVSFPTSTSSDSSGGRVIPDVRVTQHFAKEPQEPLKLHSSPASPSLASKEVGMTFSQGPGTPATTAMAPCPASLPRGYMTP---AGPERSPSTSSTIHSYGQPPTTANYGSQTEELPHAPSGPAGSGRASREKPLSGGDGEVGPPQPSRGYSYFTGSSPPLSPSTPSESPTFSPSKLGPRATAEFSTQTPSLTPSSDIPRSVGT--PSPMVAQGTQTPHRPSTPRLVWQQSSQEAPVMVITLASDASSQTRMVHASASTSPLCSPT-DSQPASHSYSQTTPPSASQMPSEPAGPPGFPRAPSAGVDGPLALYG----------WGALPAENISLCRISSVPGTSR-VEPGPRPPGTAVVDLRTAVKPTPIILTDQGMDLTSLAVEARKYGLALDPVPGRQSTAVQPLVINLNAQEQTHTFLATATTVSITMASSVLMAQQKQPVVYGDPFQSRLDFGQGSGSPVCLAQVK----------------------------QVEQAVQTAPYRGGPRGRPREAKFARYNLPNQVTP-LARRDILITQMG-----TAQSVSLKPGPVPEP------------GAEPHRATPAELRAHALPG---TRKPHTVVVQMGEGAAG--TVTTLLPEE----PAGALDLTG-MRPESRLACCDMAYKFPFGSSCTGTFHPAPSAPDKSVTDAALPGQSSGPFYSPRDPEPPEPLTFRAQGVVGPGPHEEQRPYPQGLPGRLYSSMSDTNLAEAGLNYHAQRIGQLFQGPGRDSAVDLSSLKHSYSLGFADGRYLGQGLQYGSFTDLRHPTDLLSHPLPMRPYSSVSNIYSDHRYGPRGDAVGFQEASLAQYSATTAREISRMCAALNSMDQYGGRHGGGSGGPDLVPYQPQHG-PG--LNAPQGLASLRSGLLGNPTYPEGQPSPGNLAQYGPAASQGTAVRQLLPSTATVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRGGMYRPYGSGGVTAVPLTSLTRVPMIAPRVPLGPAGLYRYPAPSRFPIAS------TIPP----AEGPVYLGKPAAAKASGAGGPPRPELPAG----GAREEPLSTTAPPAVIKEAPVAQAP----APPPGQKP--AGDAAAGSGSGVLGRP--------------------------------VMEKEEASQEDRQRKQQEQLLQLERERVELEKLRQLRLQEELERERVELQRHREEEQLLVQRELQELQTIKHHVLQQQQEERQAQFALQREQLAQQRLQLEQIQQLQQQLQQQLEEQKQRQKAPFPATCEAPSRGPPPAATELAQNGQYWP------------PLTHTAFIAVAG----TEGP---------GQAREPVLHRG-LPSSASDMSLQTEEQWEAGRSGIKKRHSMPRLRDACEPESGPDPSTVRRIADSSVQTDDEEGEGRYLLTRRRRTRRSADCSVQTDDEDNAEWE-QPVRRRRSRLSRHSDSGSDSKHEASASSS-AAAAAARAMSSVGIQTISDCSVQTEPEQLPRVSPAIHITAATDPKVEIVRYISAPEKTGRGESLACQTEPDGQAQGVAGPQLIGPTAISPYLPGIQIVTPGALGRFEKKKPDPLEIGYQAHLPPESLSQLVSRQPPKSPQVLYSPVSPLSPHRLLDTSFASSERLNKAHVSPQ-KQFIADSTLRQQTLPRPMKTLQRSLSDPKPLSPTAEESAKERFSLYQHQGGLGSQVSALPP-NGLVRKVKRTLPSPPPEEAHLPLAGQVPSQLYAASLLQRGLAGPTTVPATKASLLRELDRDLRLVEHESTKLRKKQAELDEEEKEIDAKLKYLELGITQRKESLAKDRVGRDYPPLRGLGEHRDYLSDSELNQLRLQGCTT---PAGQYVDYPASAAVPATPSGPTAFQQP--------RFPPAATQYTAGSSGPTQNGFLAHQAPTYTGPSTYPAPTYPPGTSYPAEPG-------------------LPSQPAFHP-TGHYAAPTPMPTTQSAPFPVQADSHAAHQKPRQTSLADLEQKVPTNYEVISSPAVTVSSTPSETGYSGPAVSSSYEHGKAPEHPRGGDRSSVSQSPAPTYPSDSHYTS-LEQNVPRNYVMIDDISELTKDSTPTASDSQRPEPLGPGGVSGRPGKDPGEPAVLEGPTLPCCYGRGEEESEEDSYDPRGKSGHHRSMESNGRPASTHYYSDSDYRHGARADKYGPGPMG-PKHPSKNLAPAAISSKRSKHRKQGMEQKISKFSPIEEAKDVESDLASYPPPTVSSSLTSRSRKFQDEITYGLKKNVYEQQRYYGVSSRDTAEEDDRMYGGSSRSRVASAYSGEKLSSHDFSSR-SKGYERERETAQRLQKAGPKPSSLSMAHGR-ARPPMRSQASEEESPVSPLGRPRPAGGALPPG-DTCPQFCSSHSMPDVQEH-VKDGPRAHAYKREEGYILDDSHCVVSDSEAYHLGQEETDWFDKPRDARSDRFRHHGGHTVSSS-QKRGPARHSYHDYDEPPEEGLWPHDEGGPGRHTSAKEHRHHGDHGRHSGRHAGE---EPGRRAARPHARDMGRHETRPHPQASPAPAMQKKGQPGYPSSADYSQPSRAPSAYHHASDSKKGSRQAHSG----PTVLQPKPEAQAQPQMQGRQAVPGPQQSQPPSSRQTPSGTASRQPQTQQQQQQQQQQQQQQQQQQQQQQQQGLGQQAPQQAPS---QARLQQQSQPTTRSTAPAASHPAGKPQPGPTTAPGPQPAGLPRAEQAGSSKP-AAKAPQQGRAPQAQSAPG--PAGAKTGARPGGTPGAPAGQPAAEGESVFSKILPGGAAEQAGKLTEAVSAFGKKFSSFW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88737-1", "uniprot_id": "BSN_MOUSE", "id": "O88737-1", "name": "Protein bassoon", "aln": "MGNEASLEGGAGEGPLPPGGSGLGPGPG----AGKPPSALAGGGQLPVAGAAR-AAGPPTPGLGPVPGPGPGPGPGSVPRRLDPKEPLGSQRTTSPTPKQASATAPGRESPRETRAQGPSGQEAESPRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTPS-QPNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTAPRSKSQQQLHSPALS--PAHSPAKQPLGKPEQERSP--RGPGATQSGPRQAEAARATSVPGPTQATAPPEVGRVSPQ--PPLSTKPSTAEPRPPAGEAQGKSATTVPSGLGAGEQT--QEGLTGKLFGLGASLLTQASTLMSVQPEADTQGQPSPSKGQPKIVFSDASKEAGPRPPGSGPGPGPTPGAKTEPGARMGPGSGPGALAKTGGTASPKHGRAEHQAASKAAAKPKTMPKERASACPLCQAELNMGS-RGPANYNTCTACKLQVCNLCGFNPTPHLVEKTEWLCLNCQTKRLLEGSLGEPAPLPLPTPQQPPAGVPHRAAGAAPLKQKGPQGLGQPSGSLPAKASPQATKASPQATKASPQATKASPQTTKASPQAKPLRATEPSKTSSSAQEKKTVTSAKAEPVPKPPPETTVPPGTPKAKSGVKRTDPATPVVKPVPEAPKGGEAEEPVPKPYSQDLSRSPQSLSDTGYSSDGVSSSQSEITGVVQQEVEQLDSAGVTGPR-PPSPSELHKVGSSLRPSLEAQAVAPSAEWSKPPRSSSSAVEDQKRRPHSLSITP-EAFDSDEELGDILEED-DSLAWGRQREQQDTAESSDDFGSQLRHDYVEDSSEGGLSPLPPQPPAR-ADMTDEEFMRRQILEMSAEEDNLEEDDTAVSGRGLAKHSAQKASARPRPESSQE----PKRRLPHNATTGYEELLSEA-GPAEPTDSSGALQGGLRRFKTIELNSTG-SYGHELDLGQGPDPNLDREPELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDSSPSRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQQRIRSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYSPSPSLDSEAETLDGGPTRLYKSGSEYNLPAFMSLYSPTETPSGSSTTPSSGRPLKSAEEAYEDMMRKAEMLQRQQGQVAGARGPHGGPSQPTGPRSQGSFEYQDTQDHDYGGRASQPVAESTPAGLGAAVYEEILQTSQSIARMRQASSRDLGFTEDKKKEKQFLNAESAYMDPMKQNGGPLTPGTSPTQLAAPVSFSTSTSSDSSGGRVIPDVRVTQHFAKEPQDPLKLHSSPVSSTLTSKEVGMTFSQGPGSPATTASP------TRGYMTPTSPAGSERSPSTSSTIHSYGQPPTTANYGSQTEELPHAPSGPPGSGRAPREKPLSGGDSEVGAPQPSRGYSYFTGSSPPLSPSTPSESPTFSPGKLGPRATAEFSTQTPSLTLSSDIPRSPGP--PSPMVAQGTQTPHRPSTPRLVWQQSSQEAPIMVITLASDASSQTRMVHASASTSPLCSPT-DSQPTSHSYSQTTPPSASQMPSEPAGPPGFPRAPSAGTDGPLALYG----------WGALPAENISLCRISSVPGTSR-VEPGPRPPGTAVVDLRTAVKPTPIILTDQGMDLTSLAVEARKYGLALDPVSGRQSTAVQPLVINLNAQEQTHTFLATATTVSITMASSVLMAQQKQPVVYGDPFQSRLDFGQGSGSPVCLAQVK----------------------------QVEQAVQTAPYRGGPRGRPREAKFARYNLPNQVTP-LARRDILITQMG-----TAQGVGLKPGPVPEP------------GAEPHRATPAELRSHAPPG---TRKPHTVVVQMGEGTAG--TVTTLLPEE----PAGALDLTG-MRPESQLACCDMVYKFPFGSSCTGTFHPAPSAPDKSVTDTALPGQSSGPFYSPRDPEPPEPLTFRTQGVVGPGPHEEQRPYPQGLPGRLYSSMSDTNLAEAGLNYHAQRLGQLFQGPGRDSAVDLSSLKHSYSLGFADGRYLGQGLQYGSFTDLRHPTDLLSHPLPLRRYSSVSNIYSDHRYGPRGDAVGFQEASLAQYSATTAREISRMCAALNSMDQYGGRHGSGSGGPDLVQYQPQHG-PG--LSAPQGLAPLRSGLLGNPTYPEGQPSPGNLAQYGPAASQATAVRQLLPSTATVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRGGMYRPYVSGGVTAVPLTSLTRVPMIAPRVPLGPAGLYRYPAP-RFPIAS------SVPP----AEGPVYLGKPAAAKASGAGGPPRPELPAG----VAREEPFSTTAP-AVIKEAPVAPAPGPAPAPPPGQKP--AGEAVAGSGSGVLSRP--------------------------------ASEKEEASQEDRQRKQQEQLLQLERERVELEKLRQLRLQEELERERVELQRHREEEQLLVQRELQELQTIKQHVLQQQQEERQAQFALQREQLAQQRLQLEQIQQLQQQLQLQLEEQKQRQKAPFPATCEAPSRGPPPAATELAQNGQYWP------------PLTHAAFIAVAG----TEGP---------GQPREPVLHRG-LPSSASDMSLQTEEQWEAGRSGIKKRHSMPRLRDACEPESGPDPSTVRRIADSSVQTDDEEGEGRYLVTRRRRTRRSADCSVQTDDEDNADWE-QPVRRRRSRLSRHSDSGSDSKHDATASSSTTAAATARAMSSVGIQTISDCSVQTEPEQLPRVSPAIHITAATDPKVEIVRYISAPEKTGRGESLACQTEPDGQAQGVAGPQLIGPTAISPYLPGIQIVTPGALGRFEKKKPDPLEIGYQAHLPPESLSQLVSRQPPKSPQVLYSPVSPLSPHRLLDTSFASSERLNKAHVSPQ-KQFIADSTLRQQTLPRPMKTLQRSLSDPKPLSPTAEESAKERFSLYQHQGGLGSQVSALPP-NGLVRKVKRTLPSPPPEEAHLPLAGQVPSQLYAASLLQRGLAGPTTVPATKASLLRELDRDLRLVEHESTKLRKKQAELDEEEKEIDAKLKYLELGITQRKESLAKDRGGRDYPPLRGLGEHRDYLSDSELNQLRLQGCTT---PAGQYVDYPASAAVPATPSGPTAFQQP--------RFPPAAPQYTAGSSGPTQNGFPAHQAPTYTGPSTYPAPTYPPGTGYPAEPG-------------------LPSQPAFHP-TGHYAAPTPMPTTQSAPFPVQADSRAAHQKPRQTSLADLEQKVPTNYEVIGSPAVTMSSAPPETGYSGPAVSGSYEQGKAPEHPRGSDRSSVSQSPAPTYPSDSHYTS-LEQNVPRNYVMIDDISELTKDSTPTASESQRLEPLGPGGVSGRPGKDPGEPAVLEGPTLPCCYGRGEEESEEDSYDPRGKSGHHRSMESNGRPS-THYYGDSDYRHGARADKYGPGPMG-PKHPSKSLAPAAISSKRSKHRKQGMEQKISKFSPIEEAKDVESDLASYPPPTVSSSLTSRGRKFQDEITYGLKKNVYEQQRYYGVSSRDAAEEDERMYGSSSRSRMASAYSGEKLSSHDYSSR-GKGYERERDTAERLQKAGSKPSSLSMAHGR-ARPPMRSQASEEESPVSPLGRPRPAGGALPPG-DTCPQFCSSHSMPDVQEH-VKDGPRAHAYKREEGYMLDDSHCVVSDSEAYHLGQEETDWFDKPRDARSDRFRHHGGHTVSSS-QKRGPARHSYHDYDEPPEEGLWPHDEGGPGRHTSAKEHRHHSDHGRHSGRHAGE---EPGRRAAKPHARDMGRHEARPHPQASPAPAMQKKGQPGYPSSADYSQSSRAPSAYHHASESKKGSRQAHTG----PSALQPKADTQAQPQMQGRQAAPGPQQSQPPSSRQTPSGTASRQPQTQQQQQQQQQQQ-------------GLGQQAPQQAPS---QARLQPQSQPTTRGTAPAASQPAGKPQPGPTTAPGPQPAGPPRAEQASSSKPPAAKAPQQGRAPQAQTTPGPGPAGAKPGARPGGTPGAPASQPGAEGESVFSKILPGGAAEQAGKLTEAVSAFGKKFSSFW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UPA5-1", "uniprot_id": "BSN_HUMAN", "id": "Q9UPA5-1", "name": "Protein bassoon", "aln": "MGNEVSLEGGAGDGPLPPGGAGPGPGPGPGPGAGKPPSAPAGGGQLPAAGAARSTAVPPVPGPG--PGPGPGPGPGSTSRRLDPKEPLGNQRAASPTPKQASATTPGHESPRETRAQGPAGQEADGPRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTPS-QPNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTAPRSKSQQQLHSPALS--PAHSPAKQPLGKPDQERS---RGPGGPQPGSRQAETARATSVPGPAQAAAPPEVGRVSPQ--PPQPTKPSTAEPRPPAGEAPAKSATAVPAGLGATEQT--QEGLTGKLFGLGASLLTQASTLMSVQPEADTQGQPAPSKGTPKIVFNDASKEAGPKPLGSGPGPGPAPGAKTEPGARMGPGSGPGALPKTGGTTSPKHGRAEHQAASKAAAKPKTMPKERA-ICPLCQAELNVGS-KSPANYNTCTTCRLQVCNLCGFNPTPHLVEKTEWLCLNCQTKRLLEGSLGEPTPLPPPTSQQPPVGAPHRASGTSPLKQKGPQGLGQPSGPLPAKASPLSTKASPLPSKAS--------------PQAKPLRASEPSKTPSSVQEKKTRVPTKAEPMPKPPPETTPTPATPKVKSGVRRAEPATPVVKAVPEAPKGGEAEDLVGKPYSQDASRSPQSLSDTGYSSDGISSSQSEITGVVQQEVEQLDSAGVTGPH-PPSPSEIHKVGSSMRPLLQAQGLAPS-ERSKPL--SSGTGEEQKQRPHSLSITP-EAFDSDEELEDILEEDEDSAEWRRRREQQDTAESSDDFGSQLRHDYVEDSSEGGLSPLPPQPPARAAELTDEDFMRRQILEMSAEEDNLEEDDTATSGRGLAKHGTQKGGPRPRPEPSQEPAALPKRRLPHNATTGYEELLPEG-GSAEATDGSGTLQGGLRRFKTIELNSTG-SYGHELDLGQGPDPSLDREPELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDSSPSRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQQRIRSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYSPSPSLDSEAEALDGGPSRLYKSGSEYNLPTFMSLYSPTETPSGSSTTPSSGRPLKSAEEAYEEMMRKAELLQRQQGQAAGARGPHGGPSQPTGPRGLGSFEYQDTTDREYG-QAAQPAAEGTPASLGAAVYEEILQTSQSIVRMRQASSRDLAFAEDKKKEKQFLNAESAYMDPMKQNGGPLTPGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDPLKLHSSPASPSSASKEIGMPFSQGPGTPATTAVAPCPAGLPRGYMTPASPAGSERSPSPSSTAHSYGHSPTTANYGSQTEDLPQAPSGLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSPSSPSESPTFSPGKMGPRATAEFSTQTPSPAPASDMPRSPGAPTPSPMVAQGTQTPHRPSTPRLVWQESSQEAPFMVITLASDASSQTRMVHASASTSPLCSPT-ETQPTTHGYSQTTPPSVSQLPPEPPGPPGFPRVPSAGADGPLALYG----------WGALPAENISLCRISSVPGTSR-VEPGPRTPGTAVVDLRTAVKPTPIILTDQGMDLTSLAVEARKYGLALDPIPGRQSTAVQPLVINLNAQEH--TFLATATTVSITMASSVFMAQQKQPVVYGDPYQSRLDFGQGGGSPVCLAQVK----------------------------QVEQAVQTAPYRSGPRGRPREAKFARYNLPNQVAP-LARRDVLITQMG-----TAQSIGLKPGPVPEP------------GAEPHRATPAELRSHALPG---ARKPHTVVVQMGEGTAG--TVTTLLPEE----PAGALDLTG-MRPESQLACCDMVYKLPFGSSCTGTFHPAPSVPEKSMADAAPPGQSSSPFYGPRDPEPPEPPTYRAQGVVGPGPHEEQRPYPQGLPGRLYSSMSDTNLAEAGLNYHAQRIGQLFQGPGRDSAMDLSSLKHSYSLGFADGRYLGQGLQYGSVTDLRHPTDLLAHPLPMRRYSSVSNIYSDHRYGPRGDAVGFQEASLAQYSATTAREISRMCAALNSMDQYGGRHGSGGGGPDLVQYQPQHG-PG--LSAPQSLVPLRPGLLGNPTFPEGHPSPGNLAQYGPAAGQGTAVRQLLPSTATVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRGGMYRPYASGGITAVPLTSLTRVPMIAPRVPLGPTGLYRYPAPSRFPIAS------SVPP----AEGPVYLGKPAAAKAPGAGGPSRPEMPVG----AAREEPLPTTTP-AAIKEAAGAPAP----APLAGQKP--PADAAPGGGSGALSRP--------------------------------GFEKEEASQEERQRKQQEQLLQLERERVELEKLRQLRLQEELERERVELQRHREEEQLLVQRELQELQTIKHHVLQQQQEERQAQFALQREQLAQQRLQLEQIQQLQQQLQQQLEEQKQRQKAPFPAACEAPGRGPPLAAAELAQNGQYWP------------PLTHAAFIAMAG----PEGL---------GQPREPVLHRG-LPSSASDMSLQTEEQWEASRSGIKKRHSMPRLRDACELESGTEPCVVRRIADSSVQTDDEDGESRYLLSRRRRARRSADCSVQTDDEDSAEWE-QPVRRRRSRLPRHSDSGSDSKHDATASSS-SAAATVRAMSSVGIQTISDCSVQTEPDQLPRVSPAIHITAATDPKVEIVRYISAPEKTGRGESLACQTEPDGQAQGVAGPQLVGPTAISPYLPGIQIVTPGPLGRFEKKKPDPLEIGYQAHLPPESLSQLVSRQPPKSPQVLYSPVSPLSPHRLLDTSFASSERLNKAHVSPQ-KHFTADSALRQQTLPRPMKTLQRSLSDPKPLSPTAEESAKERFSLYQHQGGLGSQVSALPP-NSLVRKVKRTLPSPPPEEAHLPLAGQASPQLYAASLLQRGLTGPTTVPATKASLLRELDRDLRLVEHESTKLRKKQAELDEEEKEIDAKLKYLELGITQRKESLAKDRGGRDYPPLRGLGEHRDYLSDSELNQLRLQGCTT---PAGQFVDFPATAAAPATPSGPTAFQQP--------RFQPPAPQYSAGSGGPTQNGFPAHQAPTYPGPSTYPAPAFPPGASYPAEPG-------------------LPNQQAFRP-TGHYAGQTPMPTTQSTLFPVPADSRAPLQKPRQTSLADLEQKVPTNYEVIASPVVPMSSAPSETSYSGPAVSSGYEQGKVPEVPRAGDRGSVSQSPAPTYPSDSHYTS-LEQNVPRNYVMIDDISELTKDSTSTAPDSQRLEPLGPG-SSGRPGKEPGEPGVLDGPTLPCCYARGEEESEEDSYDPRGKGGHLRSMESNGRPASTHYYGDSDYRHGARVEKYGPGPMG-PKHPSKSLAPAAISSKRSKHRKQGMEQKISKFSPIEEAKDVESDLASYPPPAVSSSLVSRGRKFQDEITYGLKKNVYEQQKYYGMSSRDAVE-DDRIYGGSSRSRAPSAYSGEKLSSHDFSGW-GKGYEREREAVERLQKAGPKPSSLSMAHSR-VRPPMRSQASEEESPVSPLGRPRPAGGPLPPGGDTCPQFCSSHSMPDVQEH-VKDGPRAHAYKREEGYILDDSHCVVSDSEAYHLGQEETDWFDKPRDARSDRFRHHGGHAVSSSSQKRGPARHSYHDYDEPPEEGLWPHDEGGPGRHASAKEHRHG-DHGRHSGRHTGE---EPGRRAAKPHARDLGRHEARPHSQPSSAPAMPKKGQPGYPSSAEYSQPSRASSAYHHASDSKKGSRQAHSG----PAALQSKAEPQAQPQLQGRQAAPGPQQSQSPSSRQIPSGAASRQPQTQQQQQ-------------------GLGLQPPQQALT---QARLQQQSQPTTRGSAPAASQPAGKPQPGPSTATGPQPAGPPRAEQTNGSKG-TAKAPQQGRAPQAQPAPGPGPAGVKAGARPGGTPGAPAGQPGADGESVFSKILPGGAAEQAGKLTEAVSAFGKKFSSFW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B2S6-1", "uniprot_id": "A0A8M2B2S6_DANRE", "id": "A0A8M2B2S6-1", "name": "", "aln": "MGNEASLEGEGQPG--QPGGAVPAAGAP------ASISAPAGGGQLHKP-----SNGAPAGGMG----TGHGPGMNSIQGKPNQTDPS-----MGPKPGGPPGAGPGPGAP--TQPQGPS--QSQAARKNLQVDVGGSKGG---PVSPG-SSAPTSPYSLPQIAPMPSSKLCPVCKTADLTGTTDGQPNCNKCTQCRSMVCNQCGFNPNPHLTEVQEWLCLNCQMQRALGMDMETP-RSKSQQQIHSPSQPSKPSPQPVTQPTAQPQPQPQPQPQPQPQPQPQPQHPPEAKKQTVPQAVPQSKPPAPGAVPLPGMAKAPSQPDLSRSGPGFLPQIPRQDQTRSAGSSPSRQPPPPEQPFGKLFGFGASLLNQASNLMSVDPVQTAPPTQPPTSPKP------PQKQPGP------PGPGPGPAVGTKPTAQPGP---------------PRQ---------DIPAKPKVC-------CPLCKAELNVGDPAKTPNYNLCTQCHTQVCNMCGFNPTPHLTEKKEWLCLTCQTQRAMSGSLGDITPPVPPSVGSP--RLPGPANQQQQQRGSSQQASLRPTGPQQQKPAGAQVSVPFSPVKQG-------------APQSK--GPSQQLPATKTDTKKQDQGNNKKQVMSKTEKDGDIKASSKKGTSDKKDEKKSSGIQKSKQDDDSN---------------KSSTQSLSDTGYSSDGISSSQSEITGLIQEDSMKLNERGVTDQRSPPSPSELTKLESSMRPLLESHTGTGQGQHRDGR------DNADQQRPRSLSITQDQEFESDE-------------------------EASDDLSCKLRHDYVEDSSESGLSPLPPRQKKSQKELTDEEFMRRQILEMSADEEDTADTEGHVKSKRSHKHSGDLGKER--------------RRLTQQSSSFEEDSKSADNYKSAEADDMMASQGGLRRFKTIELNNTN-SFNRDMELSTDHD---LREPELEMESLTGSPEERSRGEYSSTLPATTPSYTSGTSPTSVSSMEDDSDSSPSRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEDELREEEELLREQEKMRDLEQQRIRSTARKTKRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYSP--SMDSEAEGFEMG-SKLYKSGSEYNLPTFMSLYSPTEKTSAVSPS-TADKSLKSAEEVYEEMMRKAEMMQKQQQRAP------GGPGQQNQ--------------------------------------ERMLQTDK----------------------KQHLDSGTT----------SLSPGTSPTQISAPVSFSGNDPS----GRGAQRMQSTQSHSQS-------------------QVRMNNQTSKGG---------------------------HSGSPQSQIR---QPAPTQ---------PQGRPGVQGTAQGQVPDPGASS-------LTSKMFSYFKGSSPSTSPST---SPTHSP----TRGPAPCTISTVAPTQTS-------------------QSPHRSGAPRLARQQSSQDSPVIVITLGSGTSSQTKPATVNSSTSPLSSPTKDSQKTIYQTQHTTTKSPTSPQKYPTHQTSQHVLQRAQISERVSLPASTAISAGAQSSGSLPAGNISLCRISTVPGTSRVVEQGTIAPGSNIVDLRAPMKPAPIIMTDQGMDLTSLASDARRYSLDSETAPSR-HTAVQPLIMNLNSQAQPQVTTTTPTTVSVTVAASMFISQPKQPVVYGDPLQNRVDFGQGVGSAVCLTQNRPLITDPSIPKIDACLENLGIQQQQLQKQQQKLQQQQELLEQQLQQHHQNASFARYNLANQVQPILLKKDLVVSQNASGGTQTAVSSIAKISPLPPPPLSCSASTTPTLGHDIYGGVALELKNKPAVINLSTVNPQVMMVQLEENSTQGATVTQLVKREEPPPPVDVLDLTGQIKPENQLACCDVVYKLPFAGSCSGPFS------QRGKTTPSEPPAEPTQVHG----QQSQPINDAYQTATIQATADESKSFTLPPAGRLPPSMSDNNLAGSSLQYYQR------TDPG-DLAVDLSTMKQAYEAG-----YLGMGSQYGSYTDLRHQGSDSAPPLPLRRYGSMSNINAEYGYPPR-DLGGFQESNLAQYSATTAREISRMCAALNSMEQFGSRYTS---TPELLQYGAGRGGPAGRLNLQQGLASIRANLLYG---PDGRPTVHGQTLTNLINARQASLRSLYPPAG--RTADGMIYSTINTPIASTLPITTQPAPVLNPMLRG-AYGPYTSGGVTAVPLASLTRLPQVTPRMPLNAQAPYRYPPPNQFSATAPETLSGSVPPSSTSQEVPVYLGKPTAPGSMSTNASQKSSQPVSNMGMQSIQPAHTSMVPVQSVVNAPITHMPVDSTTMQLQSQPQTQAQSLVKGQEQTQSQPQTQPQPLTLPQKQTQAITRVFPDASASTTITTSADTEKEKEEERLRQQQEQLLQLERERVELEKLRQLRLQEELERDRVELQRHREKEHLLMQREIQELQTIKQQVLHQQQAERETQLVMQREQLAQQRMQLDQIHSLQQQLQQQLEEQKRQKTAAIEAAAVAAAAEAAAASAAAAAAATTAQGAMQGVMVGGTTPQTISIIYDQSGRIIPQEGQSVQLLPCADGQVVQAVVSTRPLPSSSSEMSLKNSE--EHGDRIMKKQNSMPRLRNGSEDES------VKRIADCSVQTDDEDAEDK-LMSRRRRTRRIADCSVQTDEEDQGEWDNQPIRRRRSRYSKHSEPAAETKSDAS-------------KSSIAIQTTNDSSCQTESDQLGRISPAIHITMAETSKVELLHYISAPERTHKGESLACQTDPEAQSHGVVAPQLSVPTTVSPYSTSLQLVGATPT-KFERRKPDPLDIGYQQAQQQ---NESPSRQPPKSPQVLYSPVSPLSPHRMLETTFASSEKLNKAHVTPQQKAFTTESPQRHQTIPRPIKSVQRSMSDPKPLSPTSEDPAKTKFSLYQSQASPASQMSALQQQNAMMRKVKRTLPSPPPDESPLPIMTPAIPHIYSSPGVSQRVLPRTAQGAMKAGLLSELK----AVEQESTKLRKQQAELEEEEKEIDAKLRCLEMGITQRKETRVKERERRELAYLRCIGDARDYMSDSELNNLRLAGVAPGTYEENGMLSRPSTAPLSQFTSDLNASQYPPTSSYVPYQYPQPQPTPTQPPTATYQIGFQPAPYPTSSQPQPGTFQPHPPQPSSYQTPGPYQTHNYGQPTYESDLGLQQPSHQGFQPPTAPLAGQTLPYPAQSMSFQPQGDMLSAHQRPRQTSLADLEQKLPTNYEVISNPSIPVATSAQDTGFSG-VYSSPLNNAYGQYRPSDQPLTERIPSPSSGYGTDGVYATNLEQNIPRNYVMIDDISELTKENMGSSDMAR----LGYGSENGPRGPTYGD-------------------GSENLYG-RTSNTYQGGVDSHGHPITSGSGGSGYYYDDYKHSSRSSGGMGSQKHSSKNLAP-AVSSKRSKHRKQGMEQKISKFSPIEEARDVESDLASY------TMTTSTGGSCTVVSRTGVKKG-YDQQKYYGS--REALEEDDRLYG-SGRSRS-TGYGMDKISSRDSSGYRSKSYER--DAMERSQRG---------THGRSGRPSMRTQNSEEESPLSPVGKPMGIGRGSVPD-DVRNQYGSSHSLPDVQDHHMRDIPKSHVYKPDDPYLADDMHCAVSDSEAYHLGQEETDWFEKPREARS---KHHGSGSHSSS-SRRGNVKHTYHDYDEPPEEDLWPQDEYGHQRHSSSTSSREHRHHGSSSGRHTSSRHTTDDPRSSRSSRSHPKDPSIRSDGRTTSSSTQKRSSDPRSGSHRDSGEYSRDPSGHHHGSSGQRGQRQPGSSRRQEPSSGSRPQQGLGEQQLQSQQGQQRSSAGQQVSAKQTGSLPPETGQQGQQQLGQTTRTQQQPLQHPGQQPATTMGASQPTTTAAGMGTGTTQQQQSKPGQAPAQARQQPGGPPTAQPAAAMAKSDIAAPAPAPAPAPTP--AVAIGSKAAPQAAKPPQIPATGIGSKAAPRPGGIGSAAQQPAEGENVLTKILQGGAAEQAGKLGDAVSALGKKFTSFW", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****.**** . * ***: ..*. . ** ****** . : .*. * * .* *** .* : : .:* .*.* ...: ** :* *:.** : :::..*:.**** .:.* .***. .*:******:*****:***.***:***:***.*.. *** *.****:. **************:*:***************** *. *******:***: . *: .*..** .:*: : . : .*. .::. *: :** .. : ** * *. . .::*. :.. * :. : .:* .. .*. *****:*****.***.****:* : .*:. * ..*:.** ***** *.. *:* .: ** *:: . .****. ****:****:*. ..*** ** *: :**.:*********.**.*****.***:* :.****: :* *: .* * * : .. *. :*:*. *.: .... . * . **:* .:: :..: :*: * : :.*. : ..: * .*. : . :: : *. : .. . *.************:*********::*:: :*:. ***. : ******: *: **:** *::: : . : . : :::**:**** : *:*** *:***:..:***********.*******: ::***:***********:*:: : : ...: **. : . * ***.::::: *: . : :* : ********** **.*. :. .::*. . * ***************:*****:******:************:**:*:***************************************:****************::************:***************************************************** *:***** :: * ::***********:**** ****..*. *.: ::.:.******.**:******::*:** :.. ***.* . *.:***.: **.*:: :: .*:*******::*****. .* ** :: ** .::. :: * . . * :* *..* : :...* *:. .* .:.:. .* :.. .*: :*** .***. ***: ***.** .*..* : .* : : :* *:***..:***. *:***::*.:****.*.:****: . ..:*****.*** ::* : : .:**. * :. *. .. * . ::* . *:*** ********:****** ** *. .**: :****:.:**:***:*********** :**:*.* :. ..* ******::***:* : . :*.****:*:*:*::::* ********* *.*:***** **.***:* : * : * . : : ::*.******.*** * * ::*::::* . ** . * .*:* * * : : ... **: :. : :*:.::**: *.:: *** *: .* *...***** ::**.:*****:.**:**..**:*.* ::. : .: * .. .:. : .:* . * .. .. :*.:.:. .*** .****.*** :.*:*: : .** * *:***::*::*. * *** * **** ***** . : ***:* *.*:*** ::: * ** * ****:.**********************:*:*.*: . *:*: * . :* *. *. *.*..:*..** . *:*:*: . : . .: :::*.* *.:. *:**************:*********.**.**:** * ** ***:*****:****:* ::**:**.. . ****.* :*. :: ::** * *******:*. : .:... :.. *.. : : . .: .* : :*. : * : .:* .:: . . . .:* :.*: .:*:* *:*****************************:*********:*:**:***:*******::**:*** **::*:.:*********:**:**:.****** ******:::.*.: *:. *.. .. *:: * . * * : : :* ** ** :.*: ****:*:***:..* * . :**::******:..* ** *:****.*******:.*.: *::****:** ********:**..:*: **:****** .:**:..:::* :*: **:.*** .*.* ***.:** *:******* * .***:::******:* :********:*:.*::**..*** **::*** ..:*:* . . :**::*****:**** .: **********************:*:*:*****:******:** * * ::*. *:**:***:*::***:*********:*:.** :***** *.. .**:*** *.::************:*: **: . .::*::. :.: : *: * **.** **. **:*******:****:**********: **:*******: .*:* *: . ** :*: ***:******:*** * :. . :. *::*. . .*. .* * * :: . . : . .. * ** . ** . *.. . ..** .. ** *.: .*:* *. *. * .:** * .* :. *:************:*******..* :.::::. :*.:** . *. ::. * . **:. * :*. *:: ****:***************:. :: :: ** * .* * *: ..*: *. * .. : .::*:*:* : ... * .. : .. ..* ** **.**.*** *:*************************:********* : .* . . *:**. *:**:*** *:: * *:*:** *.*** :.*. :*:**:* *. .*.*** :: :* *:. :*.* **.**:* ******:**:*:* * *. *. *: ****:****:* ::* *::*.** :: *: ** **.*****************:***:*** :***. : *** .:** .:*:**********.***:** * **:*:.. *. .** ****:.. . *:::. . . *.. :.:.:.: :..:* * : .: ** .*.:**.*..::*.**. :. *: . : .: *:*.:*. .. .* *::* * ... * *** :* . * : : . * *.. . :..* * .:*.* * . *::* . . . * . : ... * * . **** .* .:* . * * ..*.* *:**.*::*** ********** :****:****:***", "identical_positions": 1680, "similar_positions": 1046, "identity": "40.12%" }, { "cls_id": "homologset.agr.MGI:1277956", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q922Q4-1", "uniprot_id": "P5CR2_MOUSE", "id": "Q922Q4-1", "name": "Pyrroline-5-carboxylate reductase 2", "aln": "MS----VGFIGAGQLACALARGFTAAGVLSAHKIIASSP------DMDLPTVSALRRMGVNLTRS------------NKDTVRHSDVLFLAVKPHIIPFILDEIGADVQERHIVVSCAAGVTISSVEKKLMAFQPAPKVIRCMTNTPVVVREGATVYATGTHALVEDGKLLEQLMSSVGFCTEVEEDLIDAITGLSGSGPAYAFMALDALADGGVKMGVPRRLAVRLGAQALLGAAKMLLDSEDHPGQLKDNVCSPGGATIHALHFLESGGFRSLLINAVEASCIRTRELQSMADQEKVSPAALKKTLLDRVKLESPTVSTLAPPSSGKLLTRNPAQGSKKE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6AY23-1", "uniprot_id": "P5CR2_RAT", "id": "Q6AY23-1", "name": "Pyrroline-5-carboxylate reductase 2", "aln": "MS----VGFIGAGQLACALARGFTAAGVLSAHKIIASSP------EMDLPTVSALRKMGVNLTRS------------NKDTVRHSDVLFLAVKPHIIPFILDEIGADVQERHIVVSCAAGVTISSVEKKLMAFQPAPKVIRCMTNTPVVVREGATVYATGTHALVEDGKLLEQLMSSVGFCTEVEEDLIDAITGLSGSGPAYAFMALDALADGGVKMGVPRRLAVRLGAQALLGAAKMLLDSEDHPGQLKDNVCSPGGATIHALHFLESGGFRSLLINAVEASCIRTRELQSMADQEKVSPAALKKTLLDRVKLESPTVSTLAPPSSGKLLTRNPAQGSKRE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96C36-1", "uniprot_id": "P5CR2_HUMAN", "id": "Q96C36-1", "name": "Pyrroline-5-carboxylate reductase 2", "aln": "MS----VGFIGAGQLAYALARGFTAAGILSAHKIIASSP------EMNLPTVSALRKMGVNLTRS------------NKETVKHSDVLFLAVKPHIIPFILDEIGADVQARHIVVSCAAGVTISSVEKKLMAFQPAPKVIRCMTNTPVVVQEGATVYATGTHALVEDGQLLEQLMSSVGFCTEVEEDLIDAVTGLSGSGPAYAFMALDALADGGVKMGLPRRLAIQLGAQALLGAAKMLLDSEQHPCQLKDNVCSPGGATIHALHFLESGGFRSLLINAVEASCIRTRELQSMADQEKISPAALKKTLLDRVKLESPTVSTLTPSSPGKLLTRSLALGGKKD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1RDD0-1", "uniprot_id": "F1RDD0_DANRE", "id": "F1RDD0-1", "name": "Pyrroline-5-carboxylate reductase", "aln": "MS----VGFIGAGQLAHAMVKGFTAAGVIAANRITASSP------DTELPTVSGLRKMGVNLTTS------------NKEATHRSDVLFLAVKPHIIPFVLDEIGPDIEDRHLIVSCAAGVTISSIEKKLLQYRESPKVMRCMTNTPVVVREGATVYATGTHAHLEDGKLLEQLMASVGFCTEVEEDLIDAVTGLSGSGPAYAFTALDALADGGVKMGLPRRLAVRLGAQALMGAAKMLLDSEQHPGQLKDNVCSPGGATIHALHFLESGGFRSLLINAVEASCIRTRELQSLADQEQISAAAIKKTTLDKV-LQQPGVTHNSVGTRSRVNLFNNR--SKKS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VEJ3-1", "uniprot_id": "Q9VEJ3_DROME", "id": "Q9VEJ3-1", "name": "Pyrroline-5-carboxylate reductase", "aln": "MSAIGKIGFLGGGNMAKALAKGFLAAGLAKPNTLIASVH------PADKLSLQSFQSLGVETVIK------------NAPVVQQSDVVFVSVKPQVVPSVLSEIQP-LSSGKLFLSVAMGITLSTIESSLS---PQARVIRVMPNLPAVVCSGCSVFVRGSKATDADADITQKLLQSVGTCEPVDESQLDVVTALSGSGPAYVFVMIEALADGAVHMGMPRDLAYRLASQTVLGAGHMVRDSGMHPGQLKDGVTSPAGSTAAALRQLELSGFRAAVSGAVEQATLRCRQISGKTK-----------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32263-1", "uniprot_id": "P5CR_YEAST", "id": "P32263-1", "name": "Pyrroline-5-carboxylate reductase", "aln": "MTYT--LAILGCGVMGQALLSAIYNAPKAADETAAAFYPSKIITCNHDEPSAQQVTDLVETFDESPNGIKVESTYGHNVSAVEEASVVLLGTKPFLAEEVLNGVKS-VIGGKLLISLAAGWTIDQLS------QYTSTVCRVMTNTPAKYGYGCAVVSYSADVSKEQKPLVNELISQVGKYVELPEKNMDAATALVGSGPAFVLLMLESLMESGLKLGIPLQESKECAMKVLEGTVKMVEKSGAHPSVLKHQVCTPGGTTIAGLCVMEEKGVKSGIINGVEEAARVASQLGQKKK-----------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: :.::* * :. *: .: * . * : : . . : . * ....:.*:::..** : :*. : . : ::.:* * * *:. :. . * * *.* *. *.:* .:.. : : ::*: .** : *. :*. *.* *****:.: :::* :..:::*:* : . . :.: *: :*: .* ** **. * :*.*:* .* :* *.:: : ..** : :: . ", "identical_positions": 53, "similar_positions": 101, "identity": "15.5%" }, { "cls_id": "homologset.agr.MGI:1277957", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QYW1-1", "uniprot_id": "KCNN4_RAT", "id": "Q9QYW1-1", "name": "Intermediate conductance calcium-activated potassium channel protein 4", "aln": "--------------------------------------MGG--ELVTGLGALRRRKR--LLEQEKRVAGWALVLAGTGIGLMVLHAEMLWFLGCKWVLYLLLVKCLITLSTAFLLCLIVVFHAKEVQLFMTDNGLRDWRVALTRRQVAQILLELLVCGVHPVPLRS-PHCT--LAGEATDSQAWPGFLG--------EGEALLSLAMLLRLYLVPRAVLLRSGVLLNASYRSIGALNQVRFRHWFVAKLYMNTHPGRLLLGLTLGLWLTTAWVLSVAERQAVNATGHLTDTLWLIPITFLTIGYGDVVPGTLWGKIVCLCTGVMGVCCTALLVAVVARKLEFNKAEKHVHNFMMDIHYAKEMKESAARLLQEAWMYYKHTRRK-DSRAARRHQRKMLAAIHTFRQVRLKHRKLREQVNSMVDISKMHMILCDLQLGLSASHLALEKRIDGLAGKLDALTELLS--TALQQQQPPEPIQEAT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O89109-1", "uniprot_id": "KCNN4_MOUSE", "id": "O89109-1", "name": "Intermediate conductance calcium-activated potassium channel protein 4", "aln": "--------------------------------------MGG--ELVTGLGALRRRKR--LLEQEKRVAGWALVLAGTGIGLMVLHAEMLWFLGCKWVLYLLLVKCLITLSTAFLLCLIVVFHAKEVQLFMTDNGLRDWRVALTRRQVAQILLELLVCGVHPVPLRS-PHCA--LAGEATDAQPWPGFLG--------EGEALLSLAMLLRLYLVPRAVLLRSGVLLNASYRSIGALNQVRFRHWFVAKLYMNTHPGRLLLGLTLGLWLTTAWVLSVAERQAVNATGHLTDTLWLIPITFLTIGYGDVVPGTMWGKIVCLCTGVMGVCCTALLVAVVARKLEFNKAEKHVHNFMMDIHYAKEMKESAARLLQEAWMYYKHTRRK-DSRAARRHQRKMLAAIHTFRQVRLKHRKLREQVNSMVDISKMHMILCDLQLGLSSSHRALEKRIDGLAGKLDALTELLG--TALQQQQLPEPSQEAT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15554-1", "uniprot_id": "KCNN4_HUMAN", "id": "O15554-1", "name": "Intermediate conductance calcium-activated potassium channel protein 4", "aln": "--------------------------------------MGG--DLVLGLGALRRRKR--LLEQEKSLAGWALVLAGTGIGLMVLHAEMLWFGGCSWALYLFLVKCTISISTFLLLCLIVAFHAKEVQLFMTDNGLRDWRVALTGRQAAQIVLELVVCGLHPAPVRG-PPCVQDLGAPLTSPQPWPGFLG--------QGEALLSLAMLLRLYLVPRAVLLRSGVLLNASYRSIGALNQVRFRHWFVAKLYMNTHPGRLLLGLTLGLWLTTAWVLSVAERQAVNATGHLSDTLWLIPITFLTIGYGDVVPGTMWGKIVCLCTGVMGVCCTALLVAVVARKLEFNKAEKHVHNFMMDIQYTKEMKESAARVLQEAWMFYKHTRRK-ESHAARRHQRKLLAAINAFRQVRLKHRKLREQVNSMVDISKMHMILYDLQQNLSSSHRALEKQIDTLAGKLDALTELLS--TALGPRQLPEPSQQSK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "X1WCL6-1", "uniprot_id": "X1WCL6_DANRE", "id": "X1WCL6-1", "name": "", "aln": "MEMTARFAQLETMVDGKNCDGLVNHNGETTEIRVPLSHMGKRMSPIEGLNLYRLRDRKFLLEDKRRLCAWALGTALLGILLMVLHAELCPVVYQPGSIYALSINGLISFSTGCLLILIIAFHYKDIRLFIIDHNQVDWRIAMTSYRVLGISLELMVCAIHPVVIYLRPDGEDKLGRKPEQNSSTPLCLSSSHREVMLDVELLLSALMFLRLYLVHRAVLLHSKVLLSASYRSIGSLNNINFTFRFVLKVLMNKYPARTLLVFIMFFWLSASWMLRLCEREKQVDTGGMDTALWLIAITFLTVGYGDVSPHTSCGKVVCLFTGVMGVACTAMLVAVMTKKLALNKGEKHVHFFMMDIQISKRIRHAAANVLRECWLLHRTTQTKYTSGEHRHHQRCLLEAIRVFRHLRLKQRKLRDYASEMVDLSKMQMIMCDLSANWNSSYHELEQRIISMEQKLDELRRSFQNTSELLTQALHHRRLDYR", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** . : **. * *.* ***::: :..*** * ** *******: . :* : :: *::** ** **:.** *:::**: *:. ***:*:* :. * ***:**.:**. : * *. . .. * *. : * *** *:****** *****:* ***.*******:**::.* . ** *: **.:*.* ** : : :**:::*:* :.**: ** : :****.*****:***** * * **:*** ******.***:****:::** :**.***** *****: :*.::.:**.:*:*.*: :: *: * * *:*** :* **..**::***:****: ...***:***:**: **. . .:*: **::* : *** * . : : * : . : ", "identical_positions": 193, "similar_positions": 118, "identity": "40.12%" }, { "cls_id": "homologset.agr.MGI:1277958", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZUW5-1", "uniprot_id": "A0A8I5ZUW5_RAT", "id": "A0A8I5ZUW5-1", "name": "", "aln": "MATGGGPFEEVMHDQDLPNW--SNDSVDDRLNNMEWGGQQKKANRSSEKNKKKFGVASDKRVTNDISPESSPGVGRRRTKVPHTFPHSRYMTQMSVPEQAELEKLKQRINFSDLDQRSIGSDSQGRATAANNKRQLG-ENRKPFNFLPMQINTNKSKDATASLP----KRETTTSAQCKELFASALSN-----DLLQNCQVSEEDGRGEPAMESSQIVSRLVQIRDYITKASSMREDLVEKNERSANVERLTHLIEHLKEQEKSYMKFLQKILARENEEED---VRTIDSAVGSGSVAESTSLNVDVQSEASDTTEASFSLRIRPCIEDKLGNSASQEQVSDIDVTTSPKGKGDKAPQNDRELRPNRKCSRKRGFPSKARDPQQEPMEETENLKKQHDLLKRMLQQQEQLRALQGRQAALLALQHKAEQAIAVMDDSVVTETTGSLSGVSITSELNEELNDLIQRFHNQLRDSQP-------PAVPDNRRQAESLSLTREISQSRNPSVS-EHLPDEK---------VQLFSKMRVLQEKKQKMDKLLGELHTLRDQHLNNSSFVPSTSLPRSGDKRSSTVALSAPVGFAPAVNGESNSLISSVPCPAASLVSQNESENEGHLNPAEKLQKLNEVQKRLNELRELVHYYEQTSDMMTDAVNENTK--DEETE-----ESEYDSEHEHSEPVTNIRN---PQVASTWNEVNTNSNTQRGSNNREGRSINSSCEINNRSAANIRPLTTPL-LDCRYNREGEQRLRVARGED---EEEEVEEEGVSGASLSS--RRSSLVDEAPEDEEFEQKISRLMAAKEKLKQLQDLVAMVQDDDATQ-VLVPAASNLDDFYVAEEDTKQNSNNARENSNK--VDTGVNEKTREKFYEAKLQQQQRELKQLQEERKKLIEIQEKIQAVQKACPDLQLSATSISSGPTKKYLPAITSTPTVNENETSTS--------KCDIEPEDSSVVDNELWSDMRRHEMLREELRQRRKQLEALMAEHQRRQGLAETASPVAVSLRSDGSENLGTPQQSRTEKTMATWGGSTQCALDEDGDEDGYLSEGIVRTDEEEEEEQDASSNDNFPMYHP-SMNQNSYNVKETKNRWKNHRPVSADGN-YRPLAKTRQQNIS-------MQRQENLRWVSELSYIE--EKEQWQEQINQLKKQLDFSVNICQTLMQDQQTLSCLLQTLLTGPYSVLPSNVASPQVHLIMHQLNQCYTQLTWQQNNVQRLKQMLTELMRQQNQHPEKPRSKERGSSASHPSSPSLFCPFSFPTQPVNLLNLPGFTNFPSFAPGMNFSPLFPSNFGDFSQNVSTPTEQQQPLAQNPSGKTEYMAFPKPFESSSSLGAEKQRNQKQPEEETENTKTPWLYD-QEGGVEKPFFKTGFAVSVEKATNSNRKRQPDTSRRGRQFDEESLESFSSMPDPIDPTTVTKTFKT-RKASAQASLASKDKTPKSKSKKRNSTQLKSRVKTIGYESASVSSTCEPCKSRNRHSAQTEEPVQAKLFSRKNHEQLEKIIKYSRSAEISS-------------------ETGSDFSMFEALRDTIYSEVATLISQNESRPHFLIELFHELQLLNTDYLRQRALYALQDIVSRHISESDEKEGENIKSVNSGTWVASN-SELTPSESLVTTDDETFEKNFERET----HKITEQNDADNVSVMSVSSNFEPFATDDLGNTVIHLDQALARMREYERMKTETESNSNMRCTCRVIEDEDGAAATTTVSNAEETPIIENHSSPQPTSDVSAVPCPRIDTQQLDRQIKAIMKEVIPFLKEHMDEVCSSQLLTSVRRMVLTLTQQNDESKEFVKFFHKQLGSILQDSLAKFAGRKLKDCGEDLLVEISEVLFNELAFFKLMQDLDNNSIAVKQRCKRKIEAAGVIQSYAKEAKRILEGDRGSPAGEIDDEDKDKDETETVKQTQTSEVYDAKGPKNVRSDVSDQEEDEESERCPVSINLSKAESQALTNYGSGEDENEDEEMEDFEESPVDVQTSLQANTETTEENEHDNQVLQHDLEKTQESTNVPSDQEGTSKNDQDSSPVKPCYLNILENEQHLNSATHKDSLTTTTDSSKQPDPMPLPLTASETLVPRVKEVKSAQETPESSLAGSPDTESPVLVNDYEAESGNISQKSDEEDFVKVEDLPLKLTVCSEAELRKKMVEEEQKNHLAGEICEMQTEELA---GNPQILKEPETVGAQSV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R0L6-1", "uniprot_id": "PCM1_MOUSE", "id": "Q9R0L6-1", "name": "Pericentriolar material 1 protein", "aln": "MATGGGPFEEVMHDQDLPNW--SNDSVDDRLNNMEWGGQQKKANRSSEKNKKKFGVASDKRVTNAISPESSPGVGRRRTKIPHTFPHSRYMTQMSVPEQAELEKLKQRINFSDLDQRSIGSDSQGRATAANNKRQLS-ENRKPFNFLPMQINTNKSKDATASLP----KREMTTSAQCKELFASALSN-----DLLQNCQVSEEDGRGEPAMESSQIVSRLVQIRDYITKASSMREDLVEKNERSANVERLTHLIEHLKEQEKSYMKFLQKILAR---------------------------------------------------------------------------------------------------------DPQQEPMEETENLKKQHDLLKRMLQQQEQLRALQGRQAALLALQHKAEQAIAVMDDSVVTETTGSLSGVSITSELNEELNDLIQRFHNQLRDSQP-------PAVPDNRRQAESLSLTREISQSRNPSVS-EHLPDEK---------VQLFSKMRVLQEKKQKMDKLLGELHNLRDQHLNNSSFVPSTSLQRSGDKRSSTVALSAPVGFASAVNGEANSLISSVPCPATSLVSQNESENEGHLNPAEKLQKLNEVQKRLNELRELVHYYEQTSDMMTDAVNENTK--DEETE-----ESEYDSEHENSEPVTNIRN---PQVASTWNEVNTNSNTQCGSNNRDGRPVNSNCEINNRSAANIRALNMPP-LDCRYNREGEQRLHVAHGED---EEEEVEEEGVSGASLSS--RRSSLVDEAPEDEEFEQKISRLMAAKEKLKQLQDLVAMVQDDDATQ-VVVPAASNLDDFYAAEEDIKQNSNNARENSNK--IDTGVNEKTREKFYEAKLQQQQRELKQLQEERKKLIEIQEKIQAVQKACPDLQLSATSISSGPTKKYLPAITSTPTVNENDSSTS--------KCVIDPEDSSVVDNELWSDMRRHEMLREELRQRRKQLEALMAEHQRRQGLAETSSPVAISLRSDGSENLCTPQQSRTEKTMATWGGSTQCALDEEGDEDGYLSEGIVRTDEEEEEEQDASSNDNFPIYPP-SMNQNSYNVKETKTRWKSNRPVSADGN-YRPLAKTRQQNIS-------MQRQENLRWVSELSYIE--EKEQWQEQINQLKKQLDFSVNICQTLMQDQQTLSCLLQTLLTGPYSVLPSNVASPQVHLIMHQLNQCYTQLTWQQNNVQRLKQMLTELMRQQNQHPEKPRSKERGSSASHPSSPNLFCPFSFPTQPVNLFNLPGFTNFPSFAPGMNFSPLFPSNFGDFSQNVSTPTEQQQPLAQNPSGKTEYMAFPKPFESSSSLGAEKQRNQKQPEEEAENTKTPWLYD-QEGGVEKPFFKTGFTESVEKATNSNRKNQPDTSRRRRQFDEESLESFSSMPDPIDPTTVTKTFKT-RKASAQASLASKDKTPKSKSKKRNSTQLKSRVKNIGYESASVSSTCEPCKNRNRHSAQTEEPVQAKLFSRKNHEQLEKIIKYSRSAEISS-------------------ETGSDFSMFEALRDTIYSEVATLISQNESRPHFLIELFHELQLLNTDYLRQRALYALQDIVSRHISESDEREGENVKPVNSGTWVASN-SELTPSESLVTTDDETFEKNFERET----HKVSEQNDADNVSVMSVSSNFEPFATDDLGNTVIHLDQALARMREYERMKTETESHSNMRCTCRVIEDEDGAAAAATVSNSEETPIIENHNSPQPISDVSAVPCPRIDTQQLDRQIKAIMKEVIPFLKEHMDEVCSSQLLTSVRRMVLTLTQQNDESKEFVKFFHKQLGSILQDSLAKFAGRKLKDCGEDLLVEISEVLFNELAFFKLMQDLDNNSIAVKQRCKRKIEAAGVRQSYAKEAKRILEGDHGSPAGEIDDEDKDKDETETVKQTQTSEVYDAKGPKNVRSDVSDQEEDEESERCPVSINLSKAESQALTNYGSGEDENEDEEMEDFEESPVDIQTSLQANTETTEENEHDSQILQHDLEKTPESTNVPSDQEPTSKNDQDSSPVKPCYLNILENEQQLNSATHKDSLTTT-DSSKQPEPLPLPLAASETLVPRVKEVKSAQETPESSLAGSPDTESPVLVNDYEAESGNISQKSDEEDFVKVEDLPLKLTVYSEEELRKKMIEEEQKNHLSGEICEMQTEELA---GNSQILKEPETVGAQSI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15154-1", "uniprot_id": "PCM1_HUMAN", "id": "Q15154-1", "name": "Pericentriolar material 1 protein", "aln": "MATGGGPFEDGMNDQDLPNW--SNENVDDRLNNMDWGAQQKKANRSSEKNKKKFGVESDKRVTNDISPESSPGVGRRRTKTPHTFPHSRYMSQMSVPEQAELEKLKQRINFSDLDQRSIGSDSQGRATAANNKRQLS-ENRKPFNFLPMQINTNKSKDASTNPP----NRETIGSAQCKELFASALSN-----DLLQNCQVSEEDGRGEPAMESSQIVSRLVQIRDYITKASSMREDLVEKNERSANVERLTHLIDHLKEQEKSYMKFLKKILAR---------------------------------------------------------------------------------------------------------DPQQEPMEEIENLKKQHDLLKRMLQQQEQLRALQGRQAALLALQHKAEQAIAVMDDSVVAETAGSLSGVSITSELNEELNDLIQRFHNQLRDSQP-------PAVPDNRRQAESLSLTREVSQSRKPSAS-ERLPDEK---------VELFSKMRVLQEKKQKMDKLLGELHTLRDQHLNNS----SSSPQRSVDQRS-TSAPSASVGLAPVVNGESNSLTSSVPYPTASLVSQNESENEGHLNPSEKLQKLNEVRKRLNELRELVHYYEQTSDMMTDAVNENRK--DEETE-----ESEYDSEHENSEPVTNIRN---PQVASTWNEVNSHSNAQCVSNNRDGRTVNSNCEINNRSAANIRALNMPPSLDCRYNREGEQEIHVAQGEDDEEEEEEAEEEGVSGASLSS--HRSSLVDEHPEDAEFEQKINRLMAAKQKLRQLQDLVAMVQDDDAAQGVISASASNLDDFYPAEEDTKQNSNNTRGNANKTQKDTGVNEKAREKFYEAKLQQQQRELKQLQEERKKLIDIQEKIQALQTACPDLQLSAASVGNCPTKKYMPAVTSTPTVNQHETSTS--------KSVFEPEDSSIVDNELWSEMRRHEMLREELRQRRKQLEALMAEHQRRQGLAETASPVAVSLRSDGSENLCTPQQSRTEKTMATWGGSTQCALDEEGDEDGYLSEGIVRTDEEEEEEQDASSNDNFSVCPSNSVNHNSYNGKETKNRWKNNCPFSADEN-YRPLAKTRQQNIS-------MQRQENLRWVSELSYVE--EKEQWQEQINQLKKQLDFSVSICQTLMQDQQTLSCLLQTLLTGPYSVMPSNVASPQVHFIMHQLNQCYTQLTWQQNNVQRLKQMLNELMRQQNQHPEKPGGKERGSSASHPPSPSLFCPFSFPTQPVNLFNIPGFTNFSSFAPGMNFSPLFPSNFGDFSQNISTPSEQQQPLAQNSSGKTEYMAFPKPFESSSSIGAEKPRNKKLPEEEVESSRTPWLYE-QEGEVEKPFIKTGFSVSVEKSTSSNRKNQLDTNGRRRQFDEESLESFSSMPDPVDPTTVTKTFKT-RKASAQASLASKDKTPKSKSKKRNSTQLKSRVKNIRYESASMSSTCEPCKSRNRHSAQTEEPVQAKVFSRKNHEQLEKIIKCNRSTEISS-------------------ETGSDFSMFEALRDTIYSEVATLISQNESRPHFLIELFHELQLLNTDYLRQRALYALQDIVSRHISESHEK-GENVKSVNSGTWIASN-SELTPSESLATTDDETFEKNFERET----HKISEQNDADNASVLSVSSNFEPFATDDLGNTVIHLDQALARMREYERMKTEAESNSNMRCTCRIIEDGDGAGAGTTVNNLEETPVIENRSSQQPVSEVSTIPCPRIDTQQLDRQIKAIMKEVIPFLKEHMDEVCSSQLLTSVRRMVLTLTQQNDESKEFVKFFHKQLGSILQDSLAKFAGRKLKDCGEDLLVEISEVLFNELAFFKLMQDLDNNSITVKQRCKRKIEATGVIQSCAKEAKRILE-DHGSPAGEIDDEDKDKDETETVKQTQTSEVYD--GPKNVRSDISDQEEDEESEGCPVSINLSKAETQALTNYGSGEDENEDEEMEEFEEGPVDVQTSLQANTEATEENEHDEQVLQRDFKKTAESKNVPLEREATSKNDQNNCPVKPCYLNILEDEQPLNSAAHKESPPTV-DSTQQPNPLPLRLPEMEPLVPRVKEVKSAQETPESSLAGSPDTESPVLVNDYEAESGNISQKSDEEDFVKVEDLPLKLTIYSEADLRKKMVEEEQKNHLSGEICEMQTEELA---GNSETLKEPETVGAQSI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58GAP5-1", "uniprot_id": "A0AC58GAP5_DANRE", "id": "A0AC58GAP5-1", "name": "", "aln": "MATGGTPFEDGTDEQEMQNWTISNGSLDDRLNNMDWGVQQKKANRSSEKNRKKFSAMSESRLTNDISPESTPGAGRRRARTPHSFPHVKYSTQMSVPDQAELDRLRQVINFTDLDERSIGSDSQGRVTAANNQRQLSTEAKKPFNFLPIHLNTNKSKEPTASTSSTPGGKEHKKQSPGKELFAPVPAVVKEPFSLDGAQRLGLEDGRGELSIDSSQIVSKLVQIREYIGKATSMRDDLVEKNDVPANVERLSLLITHLKEQEKSYLRFLQKMLARENEDDDDDEGATVDSAVGSGSVAESTSLNLEPRSETSSATG---------------------------------------------------------------HGVCREQKEELENMRKQHDLLKKMLEQQEQLRALQGRQAALLAMQQSAELAIAVMDDTVVTETTGSVSGRSITSELNDELNDLIQRFHNQLHDSQAYQTVNQSQVVPDNRRQAECLSLSREVCRSRTTHNSRGQLPSSAPLTTASTSASAKLSKLQELQDKKQTMDKILQELHSLRDQTLNNSS-------CQSVSQRSARVGMSE----RPSVLGREGNGPRPVRQGSSTYTQIDDNS-----HSADKLRKLKEVHKRLNELRELVQYYEQTSDMVVDTVNENVKEEDEETEDGSLFEAMFDSEQENHEPVTNIRNPAQPQTPSNWMDMNSLTKTRSASNNRDGR-LNTECEINNRSAANLRSLNIPSVIECQHNRDRPYVGVKDEDDEEVLEDDDGARGGGGGGGRDSDGSGSSHRSSLGGDAEYAQKVHRLQTAKQKLRQLQELVAMVQSDDTDG----TTAN-------EDEGLKQQPNNTRATAPKAQRDIALCDKARERLYEEKLKQQQHELKQLHEERQRLLEIQGKIQDIQWACPDLQSSVSSSASGQMSRKIPAAASTPAPVPLQSSSSAKANTSGLKPTTEPPPVTVTDNELWTEMRRHQMLREELRQRRKQLESLMAEQQRRSTLPDSP------FRSDTHE---TQSYSRDERTVATWGGSTQCPLGDEDDD--YSSEVGAEEDDDDDERDEGEESSSTDERHACSTQKQRNYNRNNREGLKVLREVNTSPSPRRSRGRSRQQPQSERGSSSKAKRQENLRWAADLSLAEGAAPAHWQEQITHLQKQLNFSTTMCQTLLQDQQTLSYMLQALLTGPCGVVPNNVTSPQVPLIMHQLNQCYTQLAWQQNNVNRLKQTLNDLLRQQ-QSQSSSGQQQHQSVAHDPASPSMFLNYPS----VNALNIPGLPNFSPFPTGFNFAPMFPPSVGDFQQNQASSDQHHDP---NISLKTEYMSFPPPLQRSPLNNAEK-RFQSHSDNLTDANNSSWLNSSLNRSSQRPILTSDHPSQVEQNSLSSSPVPHPSTSRDRSYIPDSQESMSSLPDRADPTTVTKTFRAGRKAAAQASLASRDKTPNMKSRRKRGRGQKN-TASVDSDSVSSDSHFE----RERSNQVKYKELNQGLLDKLTQEKLDSKTKNSKPNDLSSAYAWRTPFLSNRIACTEVPDVSSDFSLFEALRETIYSEVATLISQNESRPHFLIELFHELQLLNTDYLRQRALYSLQDIVTRHLTEKSVA-DEQASSLGPAVWATGSQSELTPSESLATSDNDASDKIVTVKSNSVLKRVPDRDSMDNESLLSTSSNLEPFASDDLGNTVIHLDKALARMREYERMKLRAECNTDN-------PEHSSAIAAATVASPQGTQGAGHLS--------TDAHCPQIDTQQLDRQIKAIMTEVIPFLKEHVGEVCSQKLLKAVRHMVLNLTQQNDESKEFVRFFHRQLEGILQDSLSKFVGRKLQDCGEDLLVEISEILFNELAFFRLMQDLDQNTSKNKLRTKRRSDHTSPKHSPHTEEMKTLEREKTFSPSYFD-EDRDQDETERQEMPHEREE-----EKEKEAQSSEASEVEEEEGLPLSISLSKAETKALCNYGSGEDENEVEEMEEFEAGPVEVQTSLQASMDNTSEHRESSALQN----ETPQETKSDQDSSESSQLNSEPSDPKVIVQPPEEGGEEEKSASGDEEEEKE-DSTSAP----------------------VQETPQSSDSASPDTDSPVMINTDEAGSGNTSQRSDEEDFVKVEDLPIQMSVLCEEELCKRISEEQQNNNLTAEILNGNTSELTGLVGNAQTLKEPETIGAQSA", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***** ***: .:*:: ** ** .:*******:** ************:***.. *:.*:** *****:**.****:: **:*** :* :*****:****::*:* ***:***:**********.*****:***. * :*******:::******:.::. . :* .: *****.. : .* ::. ****** :::******:*****:** **:***:******: .******: ** *********::**:*:*** . :* ** **::*******:**:*****************:*:.** *******:**:**:**:** *******:*************:***. .*********.***:**:.:**.. * :**.. :**:: **:***.***:* ***.**** **** :* .:** . * . * *. .. .* ::: .. ::.. :.::**:**:**:**********:********:.*:**** * ***** *: :***:*: ******** **..*.* ::*: :::: ****:** :*:.**********:*.*. * ::*::**: ..:: *::: . * .*.. .* ** .. * *: **: ** :**:**:***:******.**: .:*. :*. **:.**:* .: * * .: :*:**::** **:***:*****:***::*::** *** :* ****** *.:* .. .: :** :***: ::*:* * :* ::.*****::****:**************:****:***. *.::. :*** * * . ** *:*:*********.*.::.*: * ** .. *::::*.::...... . * ::: ::.: * ..:. . *. .::*** * :*******.::** * :*****.:*:***:**..:****:******* :**:***** .*:*.**:**** :************:******:**** *.:*:*** * ... ::: * * .*.**.:* :. ** :*:**:.**..*..*:**:*:**...***.** ::. ::::* * * *****:** *:: *. .*** * :. .:: .: ..:.** . : ::*::.:... .**: : *. :. * *.: :* **:**:** *********:: ***:*******:****: **:::.. *. . .: :*.* .* * *:* . . : :: ::.: .:*:*:. * .:. ::** :..****:*****:*****************************************:*****:**::*. .*: ..:....* :.. *********.*:*::: :* . :: :::.:::. ** *::*.***:****:***********:************ .:*.::: : ..* * :** . : * : . : **:**************.*********:.****.:**.:**:***.************:***:** .******:**.****:************:********:******:*: * * **: : :. :* .* : ** :: ... :* **:*:**** : .: * *: .:: *: .* **.* *:**.*****::** ********** ****:** .**::******. : *.*:.... : : :* :..: : . :*: :.: . * *. : :**: .:. . **:. * .****:** :.****:***::* ** *** **:*************::::: .* :* *:: **:*:*:*:.** : :*.**: **.: ******:**** ", "identical_positions": 1003, "similar_positions": 576, "identity": "45.04%" }, { "cls_id": "homologset.agr.MGI:1277959", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P78352-1", "uniprot_id": "DLG4_HUMAN", "id": "P78352-1", "name": "Disks large homolog 4", "aln": "---------------------------------------------------------------------------------------------MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPN--------------------------------------QANSP---------PVIVNTDTLEAPGYELQVNGTEG-----------EMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRK-------------------PPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVG----LEDVMHEDAVAALKNTYDVVYLKVAK-PSNAYLSDSYAPPDITTS-----YSQHLDNEISHSSYLGTDYPTAMTPTSPR----RYS---------PVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSR-------------------------------------LKAKD-----------------WGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQ-GKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P31016-1", "uniprot_id": "DLG4_RAT", "id": "P31016-1", "name": "Disks large homolog 4", "aln": "---------------------------------------------------------------------------------------------MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPN--------------------------------------QANSP---------PVIVNTDTLEAPGYELQVNGTEG-----------EMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRK-------------------PPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVG----LEDVMHEDAVAALKNTYDVVYLKVAK-PSNAYLSDSYAPPDITTS-----YSQHLDNEISHSSYLGTDYPTAMTPTSPR----RYS---------PVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDAGDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSR-------------------------------------LKAKD-----------------WGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQ-GKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q62108-1", "uniprot_id": "DLG4_MOUSE", "id": "Q62108-1", "name": "Disks large homolog 4", "aln": "---------------------------------------------------------------------------------------------MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPN--------------------------------------QANSP---------PVIVNTDTLEAPGYELQVNGTEG-----------EMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRK-------------------PPAEKIIEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVG----LEDVMHEDAVAALKNTYDVVYLKVAK-PSNAYLSDSYAPPDITTS-----YSQHLDNEISHSSYLGTDYPTAMTPTSPR----RYS---------PVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFHFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSR-------------------------------------LKAKD-----------------WGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQ-GKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6R005-1", "uniprot_id": "DLG4_DANRE", "id": "Q6R005-1", "name": "Disks large homolog 4", "aln": "MPLKREDTERALQAMEACQS----AGDEGFRTRAERLLTIFQSDLFQALLDIQEFYELTVFENQ-----------------------------TAGRALTPGLKYRYHDEETPPLQHSPAHLSTGKS------------------AEMLHLGDSGHAPIDGIHAYTPQM-HVSPAKPVLLPSGHAPYYATSTLMNGMDG-----------DVEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNDVDVREVTHSFAVEALKEAGPIVRLYVLRHK-------------------PSAEKITELKLIKGPKGLGFSIAGGVGNQHVPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNNMY----LEEVMHEDAVAALKNTGDVVFLRVAKTLHQHHHQDAYNPPDITSS-----YSPHMD---------MSDYPQALSPSSPR----RYS---------PIPKGLFLDDDISREPRRVVIHRGSTGLGFNIVGGEDGEGIFISFILAGGAADLSGELRKGDQILSVNGVDLRHATHEQAAAALKNAGQTVTIITQYRPEEYSRFEAKIHDLREQLMNSSLVSAAASLRSG-KRSFFIRALFDYDKTADGGFLSQAVSFRFGDVLQVFDCSDEEWWQAGKLAPHGELEETGYIPSKRRVERKEWSR-------------------------------------LKTRG-----------------REPVS---GRSDYIVSYETVTQSEVHYARPVIILGPSKDRVNDDLLSEFPDKFGSCVPHTTRPKREYEMDGRDYHFVSSREQMEKDIQSHRFIEAGQYNSHLYGTSVQSVRQVAEQQGKHCILDVSANAVRRLQAAQLYPIAIFIRPSSLQNVLNISKRLTEEQARRALDRAVKLEQDFIECFSAIVEGESFEEIYHHVKSVIEEQSGPYIWIPARERL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P31007-2", "uniprot_id": "DLG1_DROME", "id": "P31007-2", "name": "Disks large 1 tumor suppressor protein", "aln": "MPVKKQEAHRALELLEDYHARLSEPQDRALRIAIERVIRIFKSRLFQALLDIQEFYELTLLDDSKSIQQKTAETLQIATKWEKDGQAVKIADFIKSSNLNRNCAYEFNNDASSNQTNQSALNQNPIANNVSAQAQAEALSRTFKSELEEILNQRMRIESDTENAKEPTVEQQQKQQQAQQRSSRSPQQQNPQQQQGSKSRSGSQTVNGDDSWLYEDIQLERGNSGLGFSIAGGTDNPHIGTDTSIYITKLISGGAAAADGRLSINDIIVSVNDVSVVDVPHASAVDALKKAGNVVKLHVKRKRGTATTPAAGSAAGDARDSAASGPKVIEIDLVKGGKGLGFSIAGGIGNQHIPGDNGIYVTKLMDGGAAQVDGRLSIGDKLIAVRTNGSEKNLENVTHELAVATLKSITDKVTLIIGKTQHLTTSASGGGGGGLSSGQQLSQSQSQLATSQSQSQVHQQQHATPMVNSQSTEPGSRYASTNVLAAVPPGTPRAVSTEDITREPRTITIQKGPQGLGFNIVGGEDGQGIYVSFILAGGPADLGSELKRGDQLLSVNNVNLTHATHEEAAQALKTSGGVVTLLAQYRPEEYNRFEARIQELKQQAALGAGGSGTL-LRTTQKRSLYVRALFDYDPNRDDGLPSRGLPFKHGDILHVTNASDDEWWQARRVLGDNEDEQIGIVPSKRRWERKMRARDRSVKFQGHAAANNNLDKQSTLDRKKKNFTFSRKFPFMKSRDEKNEDGSDQEPFMLCYTQDDANAEGASEENVLSYEAVQRLSINYTRPVIILGPLKDRINDDLISEYPDKFGSCVPHTTRPKREYEVDGRDYHFVSSREQMERDIQNHLFIEAGQYNDNLYGTSVASVREVAEK-GKHCILDVSGNAIKRLQVAQLYPVAVFIKPKSVDSVMEMNRRMTEEQAKKTYERAIKMEQEFGEYFTGVVQGDTIEEIYSKVKSMIWSQSGPTIWVPSKESL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *.:::: :. :..* . :* * . :. :* .. . **:* ********************** *.**:***:*.***** **** :** *: **:*.* :*.*: **:***:** :*:*:* *:: ... *: *:.*:** **********:****:****.*****:::****: ****.****::**.. **:* ** ***:**. * * * :.* .. .:::. . :: ::. .: :.. **: * . . :**.**** :.*::*. ************:**::*******.***..**::***:****.*:* :*:**:** ***.:* .**:::**:****.****:*::*::* .: *.: **: **.:::******* . * *: *:.:.*:.**:*:* :..*:***** :: ..* :: * :***** **: :* :*::. . . .: ::***:* : .::*:**:***** *** ****:**:*******************:************:**:*** * ********.:****** ***:***: *********.**::***.*:*:*:*:**:* *::.*:::.:*:*****::: :** *:**:* * *:.:*:*:::**** :** :* . *** **:*::* *", "identical_positions": 361, "similar_positions": 213, "identity": "37.14%" }, { "cls_id": "homologset.agr.MGI:1277960", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1MAD2-1", "uniprot_id": "INADL_RAT", "id": "F1MAD2-1", "name": "InaD-like protein", "aln": "----MPENPAAEKMQVLQVLDRLRGKLQEKGDTTQNEKLSAFYETLKSPLFNQILTLQQSIKQLKGQLSHIPSDCSANFDFSRKGLLVFTDGSITNGNAHRPCSSITASESLPWTQRSGNEDFTSVIQQMAQGRHIEYIDIERPSTGGLGFSVVALRSQSLGLIDIFVKEVHPGSVADRDQRLKENDQILAINDTPLDQNISHQQAIALLQQATGSLRLVVAREVGHTQSRTSTSSADTTLPETVRWGHTEDVELINDGSGLGFGIVGGKSSGVVVRTIVPGGLADRDGRLQTGDHILKIGSTNVQGMTSEQVAQVLRNCGNSVRMLVARDPVGEIAVTPPTP------ASLPVALPVVATRTLGSDSSP-FETYNVELVKKDGQSLGIRIVGYVGTAHPGEASGIYVKSIIPGSAAYHNGQIQVNDKIVAVDGVNIQGFANQDVVEVLRNAGQVVHLTLVRRKTSLSASPFEQPSSREAVAEPPEVPEL--TGSLKPETNSRMEAEEIGERLDNLRKDTVQALEKPDVYPEDIPGCPENELKSRWENLLGPDYEVMVATLDTQIADDEELQKYSKLLPIHTLRLGMEVDSFDGHHYISSIAPGGPVDTLNLLQPEDELLEVNGVQLYGKSRREAVSFLKEVPPPFTLVCCRRLFDDEASVD----------------------------------EPRTVEPSLLEAEVDRS--------------------VDVSTEDDD-GELALWSPEVKTVELVKDCKGLGFSILDYQDPLDPMRSVIVIRSLVADGVAERSGELLPGDRLVSVNEFSLDNATLAEAVEVLKAVPPGVVHLGICKPLVEEEKEEKEEHFIFHSNNNGDNSESPETVHEIHSSLILEAPQGFRDEPYL-EELVDEPFLDLGKSLQFQQKDMDSSSEAWEMHEFLSPRLERRGEEREMLVDEEYEIYQDRLRDMEAHPPPPHIREPTSASPRLDLQAGPQWLHADLSGGEILECHDTESMMTAYPQEMQDYSFSTTDMMKETFGLDSRPPMPSSEGNGQHGRFDDLEHLHSLVSHGLDLGMMTPSDLQGPGVLVDLPAVTQRREQEELPLYRLPSARVVTKPSSHVGMVSSRHANAACELPEREEGEGEETPNFSHWGPPRIVEIFREPNVSLGISIVGGQTVIKRLKNGEELKGIFIKQVLEDSPAGKTKALKTGDKILEVSGVDLQNASHAEAVEAIKSAGNPVVFVVQSLSSTPRVIPSVNNKGKTPPQNQDQNTQEKKAKRHGTAPPPMKLPPPYRAPS---ADTEESEEDSALTDKKIRQRYADLPGELHIIELEKDKNG-LGLSLAGNKDRS-----RMSIFVVGINPDGPAAADGRMRVGDELLEINNQILYGRSHQNASAIIKTAPTRVKLVFIRNEDAVNQMAVAPFPVPSHSPSPVEDLGGTEPVSSE---------------------EDSSVDAKPLPERESSKPEDLTQAVDDSMVAEQEKASESPDSAARQMKQPGYSAQVSSSSQEIPSAPAPLCQSTHADVTGSGNFQAPLSVDPAPLSVDPATCPIVPGQEMIIEISKGRSGLGLSIVGGKDTPLDAIVIHEVYEEGAAARDGRLWAGDQILEVNGVDLRSSSHEEAITALRQTPQKVRLVIYRDEAQYRDEENLEVFLVDLQKKTGRGLGLSIVGKRSGSGVFISDIVKGGAADLDGRLIRGDQILSVNGEDVRQASQETVATILK-CVQGLVQLEIGRLRAGSWASSRKTSQNSQGDQHSAHSSCRPSFAPVITS---LQNLVG---TKRSSDPPQK--CTEEEPRTVEIIRELSDALGVSIAGGKGSPLGDIPIFIAMIQANGVAARTQKLKVGDRIVSINGQPLDGLSHTDAVNLLKNAFGRIILQVVADTNISAIATQLEMMSAGSQLGS-----PTADRHPQDPEELLQRTAD---------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q63ZW7-1", "uniprot_id": "INADL_MOUSE", "id": "Q63ZW7-1", "name": "InaD-like protein", "aln": "----MPENPAAEKMQVLQVLDRLRGKLQEKGDTTQNEKLSAFYETLKSPLFNQILTLQQSIKQLKGQLSHIPSDCSANFDFSRKGLLVFTDGSITNGNAQRPCSNVTASELLPWTQKSASEDFNSVIQQMAQGRHVEYIDIERPSTGGLGFSVVALRSQSLGLIDIFVKEVHPGSVADRDHRLKENDQILAINDTPLDQNISHQQAIALLQQATGSLRLVVAREVGHTQGRASTSSADTTLPETVCWGHTEEVELINDGSGLGFGIVGGKSSGVVVRTIVPGGLADRDGRLQTGDHILKIGGTNVQGMTSEQVAQVLRNCGNSVRMLVARDPVGEIAVTPPTP------VSLPVALPAVATRTLDSDRSP-FETYSVELVKKDGQSLGIRIVGYVGTAHPGEASGIYVKSIIPGSAAYHNGQIQVNDKIVAVDGVNIQGFANQDVVEVLRNAGQVVHLTLVRRKTSLSASPFEHSSSRETVAEPPKVPER--AGSPKPEANLSVEAEEIGERLDNLKNNTVQALEKPDVYPEKVPGSPENELKSRWENLLGPDYEVMVATLDAQIADDEELQKYSKLLPIHTLRLGMEVDSFDGHHYISSVAPGGPVDTLNLLQPEDELLEVNGMQLYGKSRREAVSFLKEVPPPFTLVCCRRLFDDEASVD----------------------------------EPRTMEPALLEAEVDHS--------------------VDVNIEDDDDGELALWSPEVKTVELVKDCKGLGFSILDYQDPLDPTRSVIVIRSLVADGVAERSGELLPGDRLVSVNEFSLDNATLAEAVEVLKAVPPGVVHLGICKPLVEDEKEER---FSLHSNNNGDSSEPADAVHEIHSSLILEAPQGFRDEPYL-EELVDEPFLDLGKSLQFQQKDVDSSSEAWEMHEFLSPPLDGRGEEREMLVDEEYELYQDHLRAMESNPPPPHIREAAPASPVLELQAGTQWLHANLSGGERLECHDAESMMSAYPQEMQQYSYSTADMMEETFGLDSRAPIPSSEGNGQHGRFDDMGHLHSLTSSSLDLGMMIPSDLQGPGVLVDLPAVAQRREQEDLPLYRLPSARVVTKPSSHMGLVSSRHANAACELPEREEGEGEETPNFSHWGPPRIVEIFREPNVSLGISIVGGQTVIKRLKNGEELKGIFIKQVLEDSPAGKTNALKTGDKILEVSGVDLQNASHAEAVEAIKSAGNPVVFVVQSLSSTPRVIPTVNNKGKTPAPNQDQNTQERKAKRHGTAPPPMKLPPPYRAPS---ADMEGSEEDCALTDKKIRQRYADLPGELHIIELEKDKNG-LGLSLAGNKDRS-----RMSIFVVGINPEGPAAADGRMRIGDELLEINNQILYGRSHQNASAIIKTAPTRVKLVFIRNEDAVSQMAVAPFPELSHSPSPVEDLGGTELVSSE---------------------EESSVDAKHLPEPESSKPEDLSQVVDDNMVAEQQKESESPDSAACQIKQQTYSTQVSSSSQDSPSSPAPLCQSAHADVTGSGNFQAPLPVDPAPLSVDPATCPIVPGQEMIIEISKGRSGLGLSIVGGKDTPLDAIVIHEVYEEGAAARDGRLWAGDQILEVNGVDLRSSSHEEAITALRQTPQKVRLVVYRDEAQYRDEENLEVFLVDLQKKTGRGLGLSIVGKRSGSGVFISDIVKGGAADLDGRLIRGDQILSVNGEDMRHASQETVATILK-CVQGLVQLEIGRLRAGSWAASRKTSQNSQGDQHSAHSSCRPSFAPVITS---LQNLVG---TKRSSDPPQK--CTEEEPRTVEIIRELSDALGISIAGGKGSPLGDIPIFIAMIQANGVAARTQKLKVGDRIVSINGQPLDGLSHTDAVNLLKNAFGRIILQVVADTNISAIATQLEIMSAGSQLGS-----PTADRHPEDTEEQMQRTAD---------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NI35-1", "uniprot_id": "INADL_HUMAN", "id": "Q8NI35-1", "name": "InaD-like protein", "aln": "----MPENPATDKLQVLQVLDRLKMKLQEKGDTSQNEKLSMFYETLKSPLFNQILTLQQSIKQLKGQLNHIPSDCSANFDFSRKGLLVFTDGSITNGNVHRPSNNSTVSGLFPWTPKLGNEDFNSVIQQMAQGRQIEYIDIERPSTGGLGFSVVALRSQNLGKVDIFVKDVQPGSVADRDQRLKENDQILAINHTPLDQNISHQQAIALLQQTTGSLRLIVAREPVHTKSSTSSSLNDTTLPETVCWGHVEEVELINDGSGLGFGIVGGKTSGVVVRTIVPGGLADRDGRLQTGDHILKIGGTNVQGMTSEQVAQVLRNCGNSVRMLVARDPAGDISVTPPAP------AALPVALPTVASKGPGSDSSL-FETYNVELVRKDGQSLGIRIVGYVGTSHTGEASGIYVKSIIPGSAAYHNGHIQVNDKIVAVDGVNIQGFANHDVVEVLRNAGQVVHLTLVRRKTSSSTSPLEPPSDRGTVVEPLKPPALFLTGAVETETNVDGEDEEIKERIDTLKNDNIQALEK----LEKVPDSPENELKSRWENLLGPDYEVMVATLDTQIADDAELQKYSKLLPIHTLRLGVEVDSFDGHHYISSIVSGGPVDTLGLLQPEDELLEVNGMQLYGKSRREAVSFLKEVPPPFTLVCCRRLFDDEASVD----------------------------------EPRRTETSLPETEVDHN--------------------MDVNTEEDDDGELALWSPEVKIVELVKDCKGLGFSILDYQDPLDPTRSVIVIRSLVADGVAERSGGLLPGDRLVSVNEYCLDNTSLAEAVEILKAVPPGLVHLGICKPLVEDNEEES--CYILHSSSNEDKTEFSGTIHDINSSLILEAPKGFRDEPYFKEELVDEPFLDLGKSFHSQQKEIEQSKEAWEMHEFLTPRLQEMDEEREILVDEEYELYQDPSPSMELYP-LSHIQEATPVPSVNELHFGTQWLHDNEPS----ESQEARTGRTVYSQEAQPYGYCPENVMKENFVMESLPSVPSTEGNSQQGRFDDLENLNSLAKTSLDLG-MIPNDVQGPSLLIDLPVVAQRREQEDLPLYQHQATRVISKASAYTGMLSSRYATDTCELPEREEGEGEETPNFSHWGPPRIVEIFREPNVSLGISIVGGQTVIKRLKNGEELKGIFIKQVLEDSPAGKTNALKTGDKILEVSGVDLQNASHSEAVEAIKNAGNPVVFIVQSLSSTPRVIPNVHNKANKITGNQNQDTQEKKEKRQGTAPPPMKLPPPYKALT---DDSDENEEEDAFTDQKIRQRYADLPGELHIIELEKDKNG-LGLSLAGNKDRS-----RMSIFVVGINPEGPAAADGRMRIGDELLEINNQILYGRSHQNASAIIKTAPSKVKLVFIRNEDAVNQMAVTPFPVPSSSPSSIEDQSGTEPISSE---------------------EDGSVEVG----------------------IKQLPESESFKLAVSQMKQQKYPTKVSFSSQEIPLAPASSYHSTDADFTGYGGFQA-------PLSVDPATCPIVPGQEMIIEISKGRSGLGLSIVGGKDTPLNAIVIHEVYEEGAAARDGRLWAGDQILEVNGVDLRNSSHEEAITALRQTPQKVRLVVYRDEAHYRDEENLEIFPVDLQKKAGRGLGLSIVGKRNGSGVFISDIVKGGAADLDGRLIQGDQILSVNGEDMRNASQETVATILK-CAQGLVQLEIGRLRAGSWTSARTTSQNSQGSQQSAHSSCHPSFAPVITG---LQNLVG---TKRVSDPSQKNSGTDMEPRTVEINRELSDALGISIAGGRGSPLGDIPVFIAMIQASGVAARTQKLKVGDRIVSINGQPLDGLSHADVVNLLKNAYGRIILQVVADTNISAIAAQLENMSTGYHLGS-----PTAEHHPEDTEEQLQMTAD---------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B8K6-1", "uniprot_id": "A0A8M2B8K6_DANRE", "id": "A0A8M2B8K6-1", "name": "", "aln": "MYENVPTVSASERQQVLQALERLQSKLVQREEWTHSDRLGTLKEALQSPLFSHILTLQHSVKQLKDQLNSLPPDTCSEFSFSRKGQLIVSASRPSSSLGSVLSNGTALTN-------ASSEQLQRWIQAAAKGRKTELISLQKPLSGGLGFSVVGLRPEGVGGHGVFVRQVQPGSVADRDGRLLENDQILAINGIPLDQSVTQQQAIALLQQQKDRVELVVARDTALKPRLSASAPITTDQ-----WGHVEEIELVNDGSGLGFGIVGGKTTGMVVRTVVPGSVADKDGRLRTGDHILRIGDTMTRGLASDQVVQVLQACGAHVRMLIAREPLGAKQPAPPPAPAMGPVSSLPPPPPVPARRASRTPNLEGFEIHEVALK-KEGQSLGISIIGHN-ALTSEDAVGVYVKNVIPGSIAEQTGKIQIHDRIISLDGVNLQGYNNQEVLEVMKQSGDVVHLTLVRKIISPKRTTMEKSLDKVQRESS--------RVSLKRSSEMKARADQRGSVVESIDPALSGIKQQLQANMQEPASLTEMELRAKWEQALGPHYDVMIVQLDPVIEDDIELQKYSKLLPIHTMRLGVELDSFDGHHYISTVAPEGPVAKHGLLRPEDELLEVNGVQLYGKSRRESVAFLREVPTPFTLVCCRRLAKEDNEYHPESEDWHSYSLQEQIEHNLSMLARDTSLRDSIREEFQARQASAVEREVDDEGEPLEPISPEKEQMDQENDDDDEEEEEEDEGELALWSPNVQVLELEKAERGLGFSILDYQDPMDVARSVIVIRSLVPGGVADNHGGIFPGDQLVFVNDTHLETCSLAQAVEVLKSAPPGKVYLGIRKPLAAEDRGSG-----QQSLWPVESVDEQPTAKQAVSHTLPPMPEDFVNGSILSDDLDEEPELILDAEPRYASP--------------LTTVDLQPDVEKEMAVDEE--------------------EEDVDVNVMEDQQS----------------SKVNDTSLPSYLSEKIRS--WEEPATSSRYHLNTEPDLQEQVDDDLSMNLEKIQLQPLKIPLGHFTSWVETADSDS----------DSRNEGSELTLTDTDNE-SAQRTSSRNRKRRNQAGPTRGDLPEREEGEGEETPVFSHWGPPRRVEVWAEPEESLGISIVGGRTVIKRLKNGEELKGIFIKQVLADSPAGRTGALKTGDKILQVSGVDLQNASHEEAVQTIKAAPSPVVFIVQSLSSTPRPVSVT---ASSIKQHKAKRKAAQKAG-QGAAPPPMRLPPPYRPPSQVQEEEQEQEEEDEQDTEVIRQRYADLPGELLIVELEKDRNG-LGLSLAGNRDRS-----CMSIFVVGITTGGPASRDGRIKVGDELLEINNQVLYGRSHQNASAIIKSAASKVKLVLVRNEDAINQMAVTPFPSQPALFSSSETHENPPAVPAEKPQLPESLPLSRSPPENTLNKDQACVTATASSDPTHKSLTDGESAVKKLKPAEKLLESPSEQSAKPQVEQIPSLPKLQRSS-TKPSTGSLEVTSSASSVPVSGTSPD-----FEYCSKDPATCPIVPGQETVIEISKGRSGLGLSIVGGKDTQLDAIVIHEVYEEGAAARDGRLWAGDQILEVNGVDLRSVAHEDAIAALRQTPPKVRLTVLRDEAQYRDEENLDVFPVELQKKTGRGLGLSIVGKRNGKGVFISDVVKGGAADLDGRLMQGDQILSVDGEDMRQASQETVAAILK-CARGKVLLELGRLKAASWISSRRTSQGSQMSHASASSSTPTPTPPTVAP---PPSQTPNNNSRNIAEPISKSTVTEPGVRTVEITRGPTDALGISIAGGKGSPLGDIPIFIAMIQANGVAAKTHRLKVGDRIVSINSQSLDGLTHADVVNMLKNAYGAIILQVVADTNISAIASQVESLSSSSAPSTNPEVRLVEPETPKPKSITLEKGSEGLGFSIVGGFGSPHGDLPIYVKTVFGKGAAAVDGRLKRGDQLLSVNGESLEGVTHEQAVAILKKQRGSVTLSVLT", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9NB04-1", "uniprot_id": "PATJ_DROME", "id": "Q9NB04-1", "name": "Patj homolog", "aln": "--MHLSADISSALQQIEAVKKGIDESDDPKLQMQTAESLSTILGILQDPVFRTIVHVQDSLSELNAQLAQHPSMLPNDFDIDVAG-----------------------------------------------------------------------------------------------------NLVLSLNGGEVMYDFDEQRSSSHSHSAPGSPDKSGGVGEEPRPQSQNSKGAGVADLYATDYAQIQAIELVNDGTGLGFGIIGARNSGVIVKTILPGGVADKDGRLRSGDHILQIGDVNLHEMVSEQVAAVLRQSGTHVRLVVARP------------------VEQSVPTPQYALEPG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TAVVPTRVLVDPAELERY--------------------------------------------LISTGYPEIFGESSTASTPQTTTEDDRFVYRGETSMLIDP--------------------------------------------------------------------------------NIDLEELLALPETEKLQVELKKDANGLGITIAGYVCEKE-ELSGIFVKSVSPGSAADLSGRIRVNDRIIEVDGQSLQGYSNHQAVELLKKSGQ-VVNLRLERYLRGPK-----------------------------------------------------------------------------------------------------------------------------------------------------------------FEQLQQAIAANDKLPSSAPGTPSRAPMPTP-----------------------------------------------------------------------VATTSSATTTPSRSITRELEEEALPAPEAFMTTPPSVTTMTTTTLSSFG-------------------------------------------------------------------AGKQLVAVRDSLDGSTKIIPTEVVPLADKTEAKNSGVITRHKYYTDPELS----------------------DDAETEIIRKWQKIVGSDVEVIVAQIKKFAVGGLGISLEGTVDVEGGREVRPHHYIRSILPDGPVGVNGVLRSGDELLEVNGERLLGMNHLEVVAILKELPLDVRMVCGRNRNSS----LLPFSDDTLKKLSNN--------------------------------------------------------------FENLLPATDRLVKAKSDGSLATAGSVADGDSVAAAAASFSKLKSRSLEPLTG-------------------LAMWSSQPQIIELVKGDRGLGFSILDYQDP--------------------------------------------------------------------------------------------LDPNDTLIVIRSLVPGGVAQLDGRLIPGDRLLFVNSINLENASLDQAVQALKGASKGVVRIGVAKPLPMTDNSLKACSNASTTSEETLDAQPSPPALPTVAPPAMPPS----------------------------------------------ASMGAEPDLIPDWRN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q24008-1", "uniprot_id": "INAD_DROME", "id": "Q24008-1", "name": "Inactivation-no-after-potential D protein", "aln": "-------------MVQFLGKQGTAGELIHMVTLDKTGKKSFGICIVRG-EVKDSPNTKTTGIFIKGIVPDSPAHLCG--------------------------------------------------------------------------------------------------------RLKVGDRILSLNGKDVRN-STEQAVIDLIKEADFKIELEIQTFDKSDEQQAKSDPRSNGYMQAKNKFNQEQTTNNNASGGQGMGQGQGQGQGMAG--------MNRQQSMQKRNTTFTASMRQKHSNYADEDDEDTRDMTGRIRTEAGYEIDR---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ASAGNCKLNKQEKDRDKEQEDEFGYTMAKINKR---------------------------------------------------------------------------------------------YNMMKDLRRIEVQRDASKPLGLALAGHK---DRQKMACFVAGVDPNGALG-SVDIKPGDEIVEVNGNVLKNRCHLNASAVFKNVDGDKLVMITSR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RKPNDEGMCVKPIKKFPTASDETKFIFDQFPKARTVQVRK---------------------------------------------------------------------------------------------------------------------------------------------------EGFLGIMVIYGKHAEVGSGIFISDLR----------------------------------EGSNAELAGVKVGDMLLAVNQDVTLESNYDDATGLLKRAEGVVTMILLT-----------------------------------------------------------------------------------------LKSEEAIKAEKAAEEKKKEEAKKEEEKPQEPAT-----------------------------------AEIKPNKKILIELKVEKKPMGVIVCGGKNN----------------------------------------------------------------------------------------------HVTTGCVITHVYPEGQVAADKRLKIFDHICDINGTPIHVGSMTTLKVHQLFHTTYEKAVTLTVFRADPPELEKFNVDLMKKAGKELGLSLSP---------------------------------------------------------------NEIGCTIADLIQGQYPEIDSKLQRGDIITKFNGDALEGLPFQVCYALFKGANGKVSMEVTRPKPTLRTEAPKA-------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . ::. . : : :: : *. : :*::* : .* :. : : : * . * *:* .: *: ::: ::. : : . : ::: : :* . ... :: :. :. : . . . **::: .: : .: .: .... : .*.:: *: *. :* ::* : : : . : . . . . : : : . : : ::. *. . . :: ** ** :* : .: :. .::* * :: . . . . : : ..: :**: :*. : . :: . .* : * . * ** *:: ::. :. .* : : . . : : . . . *. ", "identical_positions": 36, "similar_positions": 155, "identity": "1.78%" }, { "cls_id": "homologset.agr.MGI:1277961", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P30427-1", "uniprot_id": "PLEC_RAT", "id": "P30427-1", "name": "Plectin", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVAGMLMPLDQLRAIYEVLFR-----------------------------EGVMVAKKDRRPRSLHPHVPGVTNLQVMRAMTSLKARGLVRETFAWCH----------------------------------------------------FYWYLTNEGIDHLRQYLHLP-----PEIVPASLQRVRRPVAMVMPARRR---------------------SPHVQTMQGPLGCPPKRGPLPAEDP-------------------------------AREERQVYRRKEREEGAP-------ETPVVSATIVGTLAR--------------------PGPEPTP---------------------------------------------------------------------------------------ATDERDRVQKKTSTKWVNKHLIK-----AQRHISDLYEDLRDGHNLISLLEVLSGDSLPREK------------GRMRFHKLQNVQIALDYLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFKIS----DIQVSGQSEDMTAKEKLLLWSQRMVEGYQGLRCDNFTTSWRDGRLFNAIIHRHKPMLIDMNKVYRQTNLENLDQAFSVAERDLGVTRLLDPEDVDVPQPDEKSIITYVSSLYDAMPRVPGAQDGVRANELQLRWQEYRELVLLLLQWIRHHTAAFEERKFPSSFEEIEILWCQFLKFKETELPAKEADKNRSKGIYQSLEGAVQAGQLKIPPGYHPLDVEKEWGKLHVAILEREKQLRSEFERLECLQRIVSKLQMEAGLCEEQLYQADSLLQSDIRLLASGKAAQRAGEVERDLDKADGMIRLLFNDVQTLKDGRHPQGEQMYRRVYRLHERLVAIRTEYNLRLKAGVGAP---VTQVTLQSTQ-----------RRPELEDSTLRYLHDLLAWVEENQRRIDGAEWGVDLPSVEAQLGSHRGMHQSIEEFRAKIERARNDESQLSPATRGAYRDCLGRLDLQYAKLLNSSKARLRSLESLHGFVAAATKELMWLNEKEEEEVGFDWSDRNTNMAAKKESYSALMRELEMKEKKIKEIQNTGDRLLREDHPARPTVESFQAALQTQWSWMLQLCCCIEAHLKENTAYFQFFSDVREAEEQLQKLQETLRRKYSCDRSITVTRLEDLLQDAQDEKEQLNEYKGHLSGLAKRAKAIVQLKPRNPAHPVRGHVPLLAVCDYKQVEVTVHKGDQCQLVGPAQPFHWKVLSSSGSEAAVPSVCFLVPPPNQEAQEAVARLEAQHQALVTLWHQLHVDMKSLLAWQSLNRDIQLIRSWSLVTFRTLKPEEQRQALRNLELHYQAFLRDSQDAGGFGPEDRLVAEREYGSCSRHYQQLLQSLEQ-----------GEQEESRCQRCISELKDIRLQLEACETRTVHRLRLPLDKDPARECAQRIAEQQKAQAEVEGLGKGVARLSAEAEKVLALPEPSPAAPTLRSELELTLGKLEQVRSLSAIYLEKLKTISLVIRSTQGAEEVLKTHEEHLKEAQAVPATLQELEVTKASLKKLRAQAEAQQPVFNTLRDELRGAQEVGERLQQRHGERDVEVERWRERVTQLLERWQAVLAQTDVRQRELEQLGRQLRYYRESADPLSSWLQDAKSRQEQIQAVPIANSQAAREQLRQEKALLEEIERHGEKVEECQKFAKQYINAIKDYELQLITYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTRYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAELEARELQRRMQEEVTRREEAAVDAQQQKRSIQEELQHLRQSSEAEIQAKAQQVEAAERSRMRIEEEIRVVRLQLETTERQRGGAEDELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEAELALRVKAEAEAAREKQRALQALDELKLQAEEAERWLCQAEAERARQVQVALETAQRSAEVELQSKRPSFAEKTAQLERTLQEEHVTVTQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQADAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLTEGTAQQRLAAEQELIRLRAETEQGEHQRQLLEEELARLQHEATAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEARRHRELAEEDAARQRAEADGVLTEKLAAISEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASESELERQKGLVEDTLRQRRQVEEEIMALKASFEKAAAGKAELELELGRIRSNAEDTMRSKELAEQEAARQRQLAAEEEQRRREAEERVQRSLAAEEEAARQRKVALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFVVQQREEELQQTLQQEQNMLERLRSEAEAARRAAEEAEEAREQAEREAAQSRKQVEEAERLKQSAEEQAQAQAQAQAAAEKLRKEAEQEAARRAQAEQAALKQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKSILDEELQRLKAEVTEAARQRSQVEEELFSVRVQMEELGKLKARIEAENRALILRDKDNTQRFLEEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQADKEQMAQQLVEETQGFQRTLEAERQRQLEMSAEAERLKLRMAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDQDAERLREAIAELEREKEKLKQEAKLLQLKSEEMQTVQQEQILQETQALQKSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAKQLQEEQQRQQQQMEQEKQELVASMEEARRRQREAEEGVRRKQEELQRLEQQRQQQEKLLAEENQRLRERLQRLEEEHRAALAHSEEIATS-----------QAAATKALPNGRDALDGPSMEAEPEYTFEGLRQKVPAQQLQEAGILSMEELQRLTQGHTTVAELTQREDVRHYLKGGSSIAGLLLKPTNEKLSVYTALQRQLLSPGTALILLEAQAASGFLLDPVRNRRLTVNEAVKEGVVGPELHHKLLSAERAVTGYKDPYTGEQISLFQAMKKDLIVRDHGIRLLEAQIATGGIIDPVHSHRVPVDVAYQRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLRLLPLTDKAAKGGELVYTDTEARDVFEKATVSAPFGKFQGKTVTIWEIINSEYFTAEQRRDLLRQFRTGRITVEKIIKIVITVVEEHERKGQLCFEGLRALVPAAELLDSGVISHEVYQQLQRGERSVREVAEADEVRQALRGTSVIAGVWLEEAGQKLSIYEALRRDLLQPEVAVALLEAQAGTGHIIDPATSARLTVDEAVRAGLVGPEMHEKLLSAEKAVTGYRDPYSGQSVSLFQALKKGLIPREQGLRLLDAQLSTGGIVDPSKSHRVPLDVAYARGYLDKETNRALTSPRDDARVYLDPSTREPVTYSQLQQRCRSDQLTGLSLLPLSEKAVRARQEEVYSELQARETLEKAKVEVPVGGFKGRALTVWELISSEYFTEEQRQELLRQFRTGKVTVEKVIKILITIVEEVETQRQERLSFSGLRAPVPASELLASKILSRTQFEQLKDGKTSVKDLSEVGSVRTLLQGSGCLAGIYLEDSKEKVTIYEAMRRGLLRASTATLLLEAQAATGFLVDPVRNQRLYVHEAVKAGVVGPELHEKLLSAEKAVTGYKDPYSGSTISLFQAMKKGLVLRDHAIRLLEAQIATGGIIDPVHSHRLPVDVAYQRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLRLLPLRGAEKTEVVETTQVYTEEETRRAFEETQIDIPGGGSHGGSSMSLWEVMQSDMIPEDQRARLMADFQAGRVTKERMIIIIIEIIEKTEIIRQQNLASYDYVRRRLTAEDLYEARIISLETYNLFREGTKSLREVLEMESAWRYLYGTGSVAGVYLPGSRQTLTIYQALKKGLLSAEVARLLLEAQAATGFLLDPVKGERLTVDEAVRKGLVGPELHDRLLSAERAVTGYRDPYTEQPISLFQAMKKELIPAEEALRLLDAQLATGGIVDPRLGFHLPLEVAYQRGYLNKDTHDQLSEPS-EVRSYVDPSTDERLSYTQLLKRCRRDDNSGQMLLPLSDARKLTFRGLRKQITVEELVRSQVMDEATALQLQEGLTSIEEVTKNLQKFLEGTSCIAGVFVDATKERLSVYQAMKKGIIRPGTAFELLEAQAATGYVIDPIKGLKLTVEEAVRMGIVGPEFKDKLLSAERAVTGYKDPYSGKLISLFQAMKKGLILKDHGIRLLEAQIATGGIIDPEESHRLPVEVAYKRGLFDEEMNEILTDPSDDTKGFFDPNTEENLTYLQLMERCITDPQTGLCLLPLKEKKRERKTSSKSSVRKRRVVIVDPETGKEMSVYEAYRKGLIDHQTYLELSEQECEWEEITISSSDGVVKSMIIDRRSGRQYDIGDAITKNLIDRSALDQYRAGTLSITEFADMLSGNAGGFRSRSSSVGSSSSYPISSAVP-RTQLASWSDPTEETGPVAGILDTETLEKVSITEAMHRNLVDNITGQRLLEAQACTGGIIDPSTGERFPVTEAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQALKKGWLYYEAGQRFLEVQYLTGGLIEPDTPGRVSLDEALQRGTVDARTAQKLRDVSAYSKYLTCPKTKLKISYKDALDRSMVEEGTGLRLLEAAAQSSKGYYSPYSVSGSGSTAGSRTGSRTGSRAGSRRGSFDATGSGFSMTFSSSSYSSSGYGRRYASGPSASLGGPESAVA-----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QXS1-1", "uniprot_id": "PLEC_MOUSE", "id": "Q9QXS1-1", "name": "Plectin", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVAGMLMPLDRLRAIYEVLFR-----------------------------EGVMVAKKDRRPRSLHPHVPGVTNLQVMRAMASLKARGLVRETFAWCH----------------------------------------------------FYWYLTNEGIDHLRQYLHLP-----PEIVPASLQRVRRPVAMVIPARRR---------------------SPHVQTMQGPLGCPPKRGPLPAEDP-------------------------------AREERQVYRRKEREEGAP-------ETPVVSATTVGTLAR--------------------PGPEPAP---------------------------------------------------------------------------------------ATDERDRVQKKTFTKWVNKHLIKHWRAEAQRHISDLYEDLRDGHNLISLLEVLSGDSLPREK------------GRMRFHKLQNVQIALDYLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQIS----DIQVSGQSEDMTAKEKLLLWSQRMVEGYQGLRCDNFTTSWRDGRLFNAIIHRHKPMLIDMNKVYRQTNLENLDQAFSVAERDLGVTRLLDPEDVDVPQPDEKSIITYVSSLYDAMPRVPGAQDGVRANELQLRWQEYRELVLLLLQWIRHHTAAFEERKFPSSFEEIEILWCQFLKFKETELPAKEADKNRSKVIYQSLEGAVQAGQLKIPPGYHPLDVEKEWGKLHVAILEREKQLRSEFERLECLQRIVSKLQMEAGLCEEQLNQADALLQSDIRLLASGKVAQRAGEVERDLDKADGMIRLLFNDVQTLKDGRHPQGEQMYRRVYRLHERLVAIRTEYNLRLKAGVGAP---VTQVTLQSTQ-----------RRPELEDSTLRYLQDLLAWVEENQRRIDSAEWGVDLPSVEAQLGSHRGMHQSIEEFRAKIERARNDESQLSPATRGAYRDCLGRLDLQYAKLLNSSKARLRSLESLHGFVAAATKELMWLNEKEEEEVGFDWSDRNTNMAAKKESYSALMRELEMKEKKIKEIQNTGDRLLREDHPARPTVESFQAALQTQWSWMLQLCCCIEAHLKENTAYFQFFSDVREAEEQLQKLQETLRRKYSCDRTITVTRLEDLLQDAQDEKEQLNEYKGHLSGLAKRAKAIVQLKPRNPAHPVRGHVPLIAVCDYKQVEVTVHKGDQCQLVGPAQPSHWKVLSGSSSEAAVPSVCFLVPPPNQEAQEAVARLEAQHQALVTLWHQLHVDMKSLLAWQSLSRDIQLIRSWSLVTFRTLKPEEQRQALRNLELHYQAFLRDSQDAGGFGPEDRLVAEREYGSCSRHYQQLLQSLEQ-----------GEQEESRCQRCISELKDIRLQLEACETRTVHRLRLPLDKDPARECAQRIAEQQKAQAEVEGLGKGVARLSAEAEKVLALPEPSPAAPTLRSELELTLGKLEQVRSLSAIYLEKLKTISLVIRSTQGAEEVLKTHEEQLKEAQAVPATLQELEATKASLKKLRAQAEAQQPVFNTLRDELRGAQEVGERLQQRHGERDVEVERWRERVTQLLERWQAVLAQTDVRQRELEQLGRQLRYYRESADPLSAWLQDAKRRQEQIQAVPIANCQAAREQLRQEKALLEEIERHGEKVEECQKFAKQYINAIKDYELQLITYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTRYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAELEAQELQRRMQEEVARREEAAVDAQQQKRSIQEELQHLRQSSEAEIQAKAQQVEAAERSRMRIEEEIRVVRLQLETTERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEAELALRVKAEAEAAREKQRALQALDELRLQAEEAERRLRQAEAERARQVQVALETAQRSAEVELQSKRASFAEKTAQLERTLQEEHVTVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQADAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQHEATAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLTEKLAAISEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAALHKADIEERLAQLRKASESELERQKGLVEDTLRQRRQVEEEIMALKVSFEKAAAGKAELELELGRIRSNAEDTMRSKEQAELEAARQRQLAAEEEQRRREAEERVQRSLAAEEEAARQRKVALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFVVQQREEELQQTLQQEQNMLDRLRSEAEAARRAAEEAEEAREQAEREAAQSRKQVEEAERLKQSAEEQAQAQAQAQAAAEKLRKEAEQEAARRAQAEQAALKQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKSILDEELQRLKAEVTEAARQRSQVEEELFSVRVQMEELGKLKARIEAENRALILRDKDNTQRFLEEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLVEETQGFQRTLEAERQRQLEMSAEAERLKLRMAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLKQEAKLLQLKSEEMQTVQQEQILQETQALQKSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAKQLREEQQRQQQQMEQEKQELMASMEEARRRQREAEEGVRRKQEELQHLEQQRQQQEKLLAEENQRLRERLQRLEEEHRAALAHS-EIATT-----------QAASTKALPNGRDAPDGPSVEAEPEYTFEGLRQKVPAQQLQEAGILSQEELQRLAQGHTTVAELTQREDVYRYLKGRSSIAGLLLKPTNEKLSVYTALQRQLLSPGTALILLEAQAASGFLLDPVRNRRLTVNEAVKEGVVGPELHHKLLSAERAVTGYKDPYTGEQISLFQAMKKDLIVRDHGVRLLEAQIATGGIIDPVHSHRVPVDVAYKRGYFDEEMNRILSDPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLRLLPLTDKAAKGGELVYTDTEARDVFEKATVSAPFGKFQGRTVTIWEIINSEYFTAEQRRDLLQQFRTGHITVEKIIKIVITVVEEHERKGQLCFEGLRALVPAAELLDSGVISHELYQQLQRGERSVREVAEADSVRQALRGTNVIAGVWLEEAGQKLSIYEALKKDLLQPEVAVALLEAQAGTGHIIDPATSARLTVDEAVRAGLVGPELHEKLLSAEKAVTGYRDPYSGQSVSLFQALKKGLIPREQGLRLLDAQLSTGGIVDPSKSHRVPLDVAYARGYLDKETNRALTSPRDDARVYHDPSTQEPVTYSQLQQRCRSDQLTGLSLLPLSEKAVRARQEEVYSELQARETLEQAKVEVPVGSFKGRAMTVWELISSEYFTEEQRQELLRQFRTGKVTVEKVIKIVITIVEEVETRRQERLSFSGLRAPVPASELLDAKILSRAQFDQLKDGKTSVKELSEVGSVRTLLQGSGCLAGIYLEDSKEKVTIYEAMRRGLLRPSTATLLLEAQAATGFLVDPVRNQRLYVHEAVKAGVVGPELHEKLLSAEKAVTGYKDPYSGNTISLFQAMKKGLVLRDHAIRLLEAQVATGGIIDPVHSHRLPVDVAYQRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLRLLPLKGAEKTEVVETTQVYTEEETRRAFEETQIDIPGGGSHGGSSMSLWEVMQSNMIPEDQRARLMADFQAGRVTKERMIIIIIEIIEKTEIIRQQNLASYDYVRRRLTAEDLYEARIISLETYNLFREGTKNLREVLEMESAWRYLYGTGAVAGVYLPGSRQTLTIYQALKKGLLSAEVARLLLEAQAATGFLLDPVKGERLTVDEAVRKGLVGPELHDRLLSAERAVTGYRDPYTEQTISLFQAMKKELIPAEEALRLLDAQLATGGIVDPRLGFHLPLEVAYQRGYLNKDTHDQLSEPS-EVRSYVDPSTDERLSYTQLLKRCRRDDPSGQMLLLLSDARKLTFRGLRKQITVEELVRSQVMDEATALQLQEGLTSIEEVTKNLQKFLEGTSCIAGVFVDATKERLSVYQAMKKGIIRPGTAFELLEAQAATGYVIDPIKGLKLTVEEAVRMGIVGPEFKDKLLSAERAVTGYKDPYSGKLISLFQAMKKGLILKDHGIRLLEAQIATGGIIDPEESHRLPVEVAYKRGLFDEEMNEILTDPSDDTKGFFDPNTEENLTYLQLMERCITDPQTGLCLLPLKEKKRERKTSSKSSVRKRRVVIVDPETGKEMSVYEAYRKGLIDHQTYLELSEQECEWEEITISSSDGVVKSMIIDRRSGRQYDIDDAITKNLIDRSALDQYRAGTLSITEFADMLSGNAGGFRSRSSSVGSSSSYPISSAGP-RTQLASWSDPTEETGPVAGILDTETLEKVSITEAMHRNLVDNITGQRLLEAQACTGGIIDPSTGERFPVTEAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQALKKGWLYYEAGQRFLEVQYLTGGLIEPDTPGRVSLDEALQRGTVDARTAQKLRDVSAYSKYLTCPKTKLKISYKDALDRSMVEEGTGLRLLEAAAQSSKGYYSPYSVSGSGSTAGSRTGSRTGSRAGSRRGSFDATGSGFSMTFSSSSYSSSGYGRRYASGPSASLGGPESAVA-----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15149-1", "uniprot_id": "PLEC_HUMAN", "id": "Q15149-1", "name": "Plectin", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVAGMLMPRDQLRAIYEVLFR-----------------------------EGVMVAKKDRRPRSLHPHVPGVTNLQVMRAMASLRARGLVRETFAWCH----------------------------------------------------FYWYLTNEGIAHLRQYLHLP-----PEIVPASLQRVRRPVAMVMPARR----------------------TPHVQAVQGPLGSPPKRGPLPTE------------------------------------EQRVYRRKELEEVSP-------ETPVVPATTQRTLAR--------------------PGPEPAP---------------------------------------------------------------------------------------ATDERDRVQKKTFTKWVNKHLIK-----AQRHISDLYEDLRDGHNLISLLEVLSGDSLPREK------------GRMRFHKLQNVQIALDYLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQIS----DIQVSGQSEDMTAKEKLLLWSQRMVEGYQGLRCDNFTSSWRDGRLFNAIIHRHKPLLIDMNKVYRQTNLENLDQAFSVAERDLGVTRLLDPEDVDVPQPDEKSIITYVSSLYDAMPRVPDVQDGVRANELQLRWQEYRELVLLLLQWMRHHTAAFEERRFPSSFEEIEILWSQFLKFKEMELPAKEADKNRSKGIYQSLEGAVQAGQLKVPPGYHPLDVEKEWGKLHVAILEREKQLRSEFERLECLQRIVTKLQMEAGLCEEQLNQADALLQSDVRLLAAGKVPQRAGEVERDLDKADSMIRLLFNDVQTLKDGRHPQGEQMYRRVYRLHERLVAIRTEYNLRLKAGVAAPATQVAQVTLQSVQ-----------RRPELEDSTLRYLQDLLAWVEENQHRVDGAEWGVDLPSVEAQLGSHRGLHQSIEEFRAKIERARSDEGQLSPATRGAYRDCLGRLDLQYAKLLNSSKARLRSLESLHSFVAAATKELMWLNEKEEEEVGFDWSDRNTNMTAKKESYSALMRELELKEKKIKELQNAGDRLLREDHPARPTVESFQAALQTQWSWMLQLCCCIEAHLKENAAYFQFFSDVREAEGQLQKLQEALRRKYSCDRSATVTRLEDLLQDAQDEKEQLNEYKGHLSGLAKRAKAVVQLKPRHPAHPMRGRLPLLAVCDYKQVEVTVHKGDECQLVGPAQPSHWKVLSSSGSEAAVPSVCFLVPPPNQEAQEAVTRLEAQHQALVTLWHQLHVDMKSLLAWQSLRRDVQLIRSWSLATFRTLKPEEQRQALHSLELHYQAFLRDSQDAGGFGPEDRLMAEREYGSCSHHYQQLLQSLEQ-----------GAQEESRCQRCISELKDIRLQLEACETRTVHRLRLPLDKEPARECAQRIAEQQKAQAEVEGLGKGVARLSAEAEKVLALPEPSPAAPTLRSELELTLGKLEQVRSLSAIYLEKLKTISLVIRGTQGAEEVLRAHEEQLKEAQAVPATLPELEATKASLKKLRAQAEAQQPTFDALRDELRGAQEVGERLQQRHGERDVEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQLRYYRESADPLGAWLQDARRRQEQIQAMPLADSQAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTAS-----------QVAATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVRHYLQGRSSIAGLLLKATNEKLSVYAALQRQLLSPGTALILLEAQAASGFLLDPVRNRRLTVNEAVKEGVVGPELHHKLLSAERAVTGYKDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLCLLPLTDKAAKGGELVYTDSEARDVFEKATVSAPFGKFQGKTVTIWEIINSEYFTAEQRRDLLRQFRTGRITVEKIIKIIITVVEEQEQKGRLCFEGLRSLVPAAELLESRVIDRELYQQLQRGERSVRDVAEVDTVRRALRGANVIAGVWLEEAGQKLSIYNALKKDLLPSDMAVALLEAQAGTGHIIDPATSARLTVDEAVRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSVSLFQALKKGLIPREQGLRLLDAQLSTGGIVDPSKSHRVPLDVACARGCLDEETSRALSAPRADAKAYSDPSTGEPATYGELQQRCRPDQLTGLSLLPLSEKAARARQEELYSELQARETFEKTPVEVPVGGFKGRTVTVWELISSEYFTAEQRQELLRQFRTGKVTVEKVIKILITIVEEVETLRQERLSFSGLRAPVPASELLASGVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQGSGCLAGIYLEDTKEKVSIYEAMRRGLLRATTAALLLEAQAATGFLVDPVRNQRLYVHEAVKAGVVGPELHEQLLSAEKAVTGYRDPYSGSTISLFQAMQKGLVLRQHGIRLLEAQIATGGIIDPVHSHRVPVDVAYQRGYFSEEMNRVLADPSDDTKGFFDPNTHENLTYRQLLERCVEDPETGLRLLPLKGAEKAEVVETTQVYTEEETRRAFEETQIDIPGGGSHGGSTMSLWEVMQSDLIPEEQRAQLMADFQAGRVTKERMIIIIIEIIEKTEIIRQQGLASYDYVRRRLTAEDLFEARIISLETYNLLREGTRSLREALEAESAWCYLYGTGSVAGVYLPGSRQTLSIYQALKKGLLSAEVARLLLEAQAATGFLLDPVKGERLTVDEAVRKGLVGPELHDRLLSAERAVTGYRDPYTEQTISLFQAMKKELIPTEEALRLLDAQLATGGIVDPRLGFHLPLEVAYQRGYLNKDTHDQLSEPS-EVRSYVDPSTDERLSYTQLLRRCRRDDGTGQLLLPLSDARKLTFRGLRKQITMEELVRSQVMDEATALQLREGLTSIEEVTKNLQKFLEGTSCIAGVFVDATKERLSVYQAMKKGIIRPGTAFELLEAQAATGYVIDPIKGLKLTVEEAVRMGIVGPEFKDKLLSAERAVTGYKDPYSGKLISLFQAMKKGLILKDHGIRLLEAQIATGGIIDPEESHRLPVEVAYKRGLFDEEMNEILTDPSDDTKGFFDPNTEENLTYLQLMERCITDPQTGLCLLPLKEKKRERKTSSKSSVRKRRVVIVDPETGKEMSVYEAYRKGLIDHQTYLELSEQECEWEEITISSSDGVVKSMIIDRRSGRQYDIDDAIAKNLIDRSALDQYRAGTLSITEFADMLSGNAGGFRSRSSSVGSSSSYPISPAVS-RTQLASWSDPTEETGPVAGILDTETLEKVSITEAMHRNLVDNITGQRLLEAQACTGGIIDPSTGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQALKKGWLYYEAGQRFLEVQYLTGGLIEPDTPGRVPLDEALQRGTVDARTAQKLRDVGAYSKYLTCPKTKLKISYKDALDRSMVEEGTGLRLLEAAAQSTKGYYSPYSVSGSGSTAGSRTGSRTGSRAGSRRGSFDATGSGFSMTFSSSSYSSSGYGRRYASGSSASLGGPESAVA-----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9P1W1-1", "uniprot_id": "A0A8M9P1W1_DANRE", "id": "A0A8M9P1W1-1", "name": "Plectin", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDALLDWALAYP--------------ALARLLWVMVLVLATVVVWSLFFCCWGNRSSTSP-----------------LEKYLSAMEKQSKTKHQSQRKKKPKDKSVSAALLNEGIAGVIKLASPLSQ----------------------------------------------------EKHKKKKEKLGNKTEE-------EDEKKEGKDENKEEGKEEKTITVRKR------------------NKKHLKVTIAPGTVTSASAGQVMSGGR------------------------------------RRMLERSASEESAS----DLSTSPFPGDTLPWNLPKHQRVKR----------SKSASGDVLDP-------------------------------------------------------AERAVIR-------------------------IADERDRVQKKTFTKWVNKHLVKHWKAEAQRHITDLYEDLRDGHNLISLLEVLSGETLPREK------------GRMRFHKLQNVQIALDFLKHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQIS----DIQVNGQSDDMTAKEKLLLWSQRMVEGYQGLRCDNFTTSWRDGRLFNAIIHKHRPNLIDINKVYRQTNLENLEQAFSIAERDLGVTRLLDPEDVDVPHPDEKSIITYVSSMYDVMPRVPDVRDGVKANELELRWQEYYELVTMLLQWIRHHVIVFEERKFPSSYEEIEVLWRQFLKFKETELPAKETDKNRSKLIYKSFEGAVQAGQVKVPPNYHPIDVEKEWGRLHVAILEREKLLRSEFERLERLQRIVSKVQMESGVCEEQLNQVETLLQTDIRLLSAGKPIQHASDIETDLNKAENMIRYLFNDVQLLKDGRHLQAEQMYRRVYRLHERLVNLRSEFNLRLKSGVTLSQVPMTQVPMTQISHVQTLQQSPQRVRPDLDEVTLKYIQDLLSWVEENQRRIEGAEWGEDLPSVESQLGSHRGLHQSIEEFKYKIDRARADENQLTPVSKGAYREYLGKLDLQYAKLLTSSKTRLRSLDQLHAFVVAATKELMWLNEKEEEEVNYDWSDRNSNMTAKKDNYSGLMRDLEQREKRVNNVQMTGDKLLKDGHPARKTIEAFTAALQTQWSWILQLCCCIETHLKENTAYFQFFSDVKEAEDRMKKMEDTMKKKYVCDRSITVTRLEDLLQDAVEEKEQLNEFKTHLEGLNRRAKTIIQLKPRNPAQPIKGKLPVQAVCDFKQMEITVHKGDECALVNNSQPYKWKVRDSSGNEAVVPSICFIVPPTNKEAVDVSSGLDGSQQRLMVLWQKLHVDMKSLLSWQYLMRDITLINSWNFIMFKTLRVEEYRLTLKNLEQHYQAFLRDSQDSGLFGADDRMQAENSYNKATQHYDNLLRSVEQEPALIQKDSTSGEQDESVCKSYITQIKDLRLRLEGCESRTVNRLRQMVDKEPLKACTQRATEQKKVQTELEGIKKDLDKVVEKSEAVLATSQQSSSAPVLRSEIDITQKKMEHVYGLSSVYLDKLKTIDLVIRSTQGAEDILNKYENQLREVNKVPVNEKEIEASQTQLQKLRSEAEGKQATFDRLEEELQRATEVNKRMSQLHSERDVELEHYRQLVGNLRERWQAVFAQIELRQRELDLLNRQMQAYRESYDWLIRWIADAKQRQDKLHAVPIGGSKGLQEQLTQEKKLLEEIEKNKDKVEDCQKFAKGYIDAIKDYELQLVTYKALVEPIASPLKKAKMESASDDIIQEYVTLRTRYSELMTLSSQYIKFIIETQRRLQDEEKAAEKLKEEERKKMAEMQAELEKQKQLAETHAKAIAKAEQEANELKTKMKDEVSKRQDVAVDSEKQKHNIQRELQELKTLSEQEIKAKSQQVEEALLSRTRIEEEIHIIRLQLETTMKQKNTAETELLQLRAKAVDADKLRNAAQEEAEKLRKQVAEETQKKRKAEEELKRKSEAEKDAAKEKKKALEDLEKFKLQAEEAERHLKQAELEKQRQIQVVEEVAKKTAATQLESK---QVALTARLEESLKNEQVMVIQLQEEAEHLKKQQAEADKAREQAEKELETWRQKANEALRLRLQAEEEANKKTAAQEEAEKQKEEAKREAKKRAKAEEAALKQKEAAEMELGNQRKMAEETAKQKLAAEQELIRLRADFEHAEQQRTVLDDELQRLKNDVNSAVKQKKELEEELIKVRKEMEILLQQKSKAEKETMSNTEKSKQLLESEAAKMRELAEEATKLRSVAEEAKKQRQIAEEEAARQRAEAEKILKEKLTAINEATRLKTEAEIALKEKEAENDRLKRKAEEEGYQRKVLEDQAAQHKQAIEEKIGQLKKSSDTELDRQKKIVEETLKQRKVVEEEIHILKLNFEKASSGKQELELELKKLKGIADETQKSKAKAEEEAEKFRKLALEEEKKRKEAEAKVKQIQAAEEEAARQHKAAQEEVGRLMKLAEEAKKQKEIAEKEAEKQVILVQEAAQKCSAAEQKAQNVLVQQNKDSMAQ---------DKLKEEFEKAKKLAQEAEKAKDNAEKEAALLHKKAEEAERQKKAAEAEAAKQAKAQEDAEKLRKEAEKEASRRAEAEAAALKLKQEADSEMAKYKKLAEKTLKQKSSVEEELVKVKVQLDETDKQKSVLDVELKRLKQEVSDAIKQKAQVEDELSKVKIQMEDLLKLKLKIEKENQELMKKDKDNTKKLLEEEAENMKKLAEEAARLNIEAQEAARLRQIAESDLAKQRELAEKMLEEKKQAIQEAAKLKAEAEKLQKQKDQAQVEAQKLLEAKKEMQQRLDQETEGFQKSLEAERKRQLEITAEAEKLKVKVTQLSDAQSKAEEEAKKFKKQADEIKIRLQETEKHTSEKHTVVEKLEVQRLQSKQEADGLHKAIADLEKEKEKLKKEAADLQKQSKEMANVQQEQLQQEKTILQQSFFAEKETLLKKEKAIEEEKKKLEKQFEDEVKKAEALKAEQERQRKLMEEERKKLQSAMDAAIKKQKEAEEEMNGKQKEMQDLEKKRIEQEKLLAEENKNLREKLQQLQSSQKASYTKEIEIQTDKVPEEELVQMTMVETTKKVLNG--STEVDGVKKDVPLAFDGIREKVPASRLHEIGVLSKKEYDKLKKGKTTVQELSKNDKVKMCLKGKDCIGGVIVEP-NQKMSIYQALKDKMITQSTAIMLLEAQAASGYIIDPIKNRRLSVSESVKDGLIGPELHTKLLSAERAVTGFKDPFTGDTISVFEAMKKGLITEDQAIKLLDCQYATGGIIDPVNSHHVPVQLACTQGQLDEDLSKILSSPPADKKAFIDPNTKDSLTYSELLDQCKPDAETGIPLLPITEQAAQS-ERTYSDEETKDVFSKANLTVPFGRFKGKTVTIWEVINSEYFTEDQRKDLIRQYKTGKITVEKIIRIVITVVEDKENKKEPAFDGLRSSVPASELLEAKVINKDLFNKLHNGKATLKDVSELEPVKKALKGTHSIAGVQIESTSEKMSLYDAMKKNLLGTEPALNLLEAQAGTGFIIDPVKNQKLTVDEAVKSGVVGPELHEKLLSAERAVCGYKDPYTGKTVSLFEAMQKDLIKKEQGVRLLEAQLATGGIIDPEKSYRITPDIAYKRGHLNEEMNQNLSKPSDLSTVYVDPNTQEKVTYTELLKRCITDKQTGLPLIPLSEKAIKSKDIEPVSDAQTKENLSHATVELHSGLFKGRVITIWEIINSEYFTEEQRIEFIRQYRSGKITIEKLIKIVISTVDEKEKKRQDN--FDGLRGPVPASSLLESKIIDKDTYDKILQGKKKPAEVSG--SVKQYLQGSDCIAGVFFQKTKEKLSIYQAMKQKLLTSDTGMSLLEAQAATGYIIDPIRNEMFTVDDAVKAGIVGPEVHEKLLSAEKAVTGYKDPYTGNKISLLQAMQKQLVLREHAIPLLDAQVATGGIIDPVNSHRLPNDVAIERGYFSKQLAKSFKDPTDDIKGFTDPNKDENVTYKQLKERCMTDPEFGVALLPLSKAQTHEEAEKSYVYTEEQAQTDLANTQIDIPHE-RFAGKQVTLWEVMKSDMLPEEEKQRLLEQYRSGKITKERMVIIIIEIIEQREIIKTEQSMSCDVIRRRVTIDELYRARIIDLETYNLLKQGKKAIREVMEMPSVKQYLFGTGSISGVLSD-NYAKVSIYQAMKRGLIKPDIGIDLLEAQAATGFMIDPVKDELLTVDEAVRKGLVGPEFHDKLLSAERAVTGYKDPYSGKVISLFQAMKKDLVPEDYAMKLLEAQVATGGLMDPEYYFRLPIDIAMQRGYMNKETSERISDPSGDVNQFIDPTTDEKVSYASLLKRCKVDKESGLRLLSLADKR-LLFKGLRKQITPEELLRSQIIDQKTYTGLMEGTISVEDLSKDLKKYLEGISSIAGVFVEATKDRLSVYQAMKKTMIRPGTAFELLEAQAATGYIIDPIKNLKMNVQEAVKMGVVGPEFKDKLLSAERAVTGYKDPYSGKVISLFQAMKKGLILKDHGIRLLEAQIATGGIIDPEESHRLPVEMAYKRGLFDEEMNGILTDPSDDTKGFFDPNTEENLTYLQLMERCMTDTETGLSLLLLKEKKRERKTSSKSSVRKRRVVIVDPETGKEMSVYEAYRKGLIDHQTYIELAEQECEWEEITTSSSDGVVKSMIIDRRSGRQYDIDDAISKGLIDQSALDQYRAGTLSITEFADMLSGNMSGFRSRSSSFGSSSSYPMSPVPSIKTPATTWTDPTEETGPVAGILDTDTLEKVSVTEAMHRNLVDNITGQRLLEAQACTGGIIDPNTGEKFSVADAQNKGLVDKIMVDRINLAQKAYQGFEDPRTKTKMSAAQALKKGWLYYEAGQRFLEVQYLTGGLIEPDVTGRVSLDEAVRKGSLDARTAQKLRDVSGYSKYLTCPKTKLKISYKDAIDRSMIEEGSGLRLLEASSQSSKGLYSPYSISGSGSTSGSRSGSRTGSRSGSRRGSFDATGSGFSMGFSSS-YSPTSYGRRYDSGVHGGHQMDELKQALTALASGRNCCYDEKRIFTSSHTQTSLVA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9PDC8-1", "uniprot_id": "A0A8M9PDC8_DANRE", "id": "A0A8M9PDC8-1", "name": "", "aln": "MVAGMVMPLDNLRAIYEHLFRDGVMVAKKDKRPQTKHPEIAGVQNLQVIRAMGSLKSRGYVTETFAWRHFYWYLTNEGIVYLRDYLHLPAEIVPTPLQRVRRPVATLAVTRRAERVQTIEGPTSYVPKPGKMGAEKQDRQGYRRKTASTDEAEVIESNERTPQFRGRPMASAQIKPKGSWESKELPIRSDNRDYTKEMEPSARRKVAMHSFSHETHHAKPVEQERMVECTKTAFIQDMPKASPGVLTISSAAVESPLVPVHSEAIKEKPKVDVSRQSTSITTAKEAHHPTPSKLKVEKTEKALVSRKMDHVPNVASAEETIALESFVHAQENPKEEEFTKVTKQTTSTTTGALRATPSKPKVDKTQETMVAKNELDVSNESSKPPVSIEAAKTKPKQDVCIKVSEKTTVVNASKMAEGDAHLTSSGPKVDKSNNVPAVSAALEISAFKSSVSSVSTEAIKEIPKEESCVSKEITSKGDSNAASHHSQLKTKGEKRQKATKTKSVQDSTCVPPAEEMSVVKPSGSEAVKEKTEEEVCVKLSQQSALKGEGGIEKDAPHPTVSSPQVEKAQKTRKNKKVQDLPMFSSTVQSSEKAEKPKDDESTKVTKEITLPVTDESKMAIDAPHPTHVEKTVKTIVTKNVQDGTSLKSPVCSVPAETANEKSNKEVCGIVSQETSSKDDNKTAFSAPSKSKVGKTATRIKNVQDKPAISSAVETTVVASSTFSLSTETIKEQYKEKVCVIASQETPFKGDKKNYAFHSATSTQKMEKMQTTKTAQTKPAVSSAEEMMEVKSSMSTEAVNEKSKREVGGIVTQETTSNGDNKKDALHPAVSKSKVVKILESKNAHDSTVVSSWMEAEVKSTLISTDAEKPKEEVCLMVSQETTLTGGSTEDAPSKLKAEKTKKTKKAKKVQDVPMISSTEAATAAESSVISVPAEKPEEDALRKVPQEATFTATDESKIDFTPSKPGGPKGTKRTKNVQELTVKLEKEQVPAVQAEEVKSNIFVTPQTPSGMPKKEENVAGETAKKKAELNLKKGVTVTSAQAQANTTVQVTDKQHDSQTSQGVIEDDSTSYLKVHKEVAIPCAISISEVKAEVKGHKPVLSPKFQPTVAEEEMTTADSSKASEISTKAESKVDTPKSHQEKASTLTEEPKTPKDKDAEETSKPSKGKKKKKTSKTSAVKEIPSLAETEVVTPAQVDPSKAEDHRQVATSNNSAKTSPEGMHAPENRQPTAVQSEAPAHKGEVEPAQPVTEKREVQKGKTSSSRRQWEAPAASASAAPAGLAAQHTPLPAQGDPPSIAQHTDTQRSTHKHCKLSHSKAPAGPVDEKTGDGQAQTTDDAMRKKIVVVEEVIEVQQVVSPVAGQPTTSPVPKVAGDDLDYDVLEELAIERGLLEGEETFWDHSLQEPEEKTFPNFVEDERDRVQKKTFTKWVNKHLIKHWRSETQRHVNDLYEDLRDGHNLISLLEVLSGETLPRERDVVRSVRLPRERGRMRFHKLQNVQIALDFLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQVSYSISDIQVNGQSDDMSAKEKLLFWSQRMVDGYHGIRCDNFTTSWRDGKLFNAIIHKHEPRLIDMPKVYRQTNMENLEQAFTVAEKELGVTRLLDPEDVDVPHPDEKSIITYVSSLYDAMPRVPDVQDGAKTNELELRWQEYYQLVTVLQQWIRHHVLIFEERRFPSSYEEVEILWRQFLKFKETELPPKESDKGRSKQLFQSFESAVQAGQIKVPPGYHPIDVEKEWGRLHVAILERERLLRIEFERLERLQQIVSKVQMESGVCEEQLNQTESLLQTDIRLLNAGKPAQHTVEVERDLDKADGMIRLLFNDVQMLKDGRHLQAEQMYRRVYRLHERLVNLRSDYNLRLKS----TATAATHTTVTSIS-----QKSVQRVRPELDEVTLRYAQDLLAWVEENQRRIDTAEWGIDLPTVESQLGSHRGLHQTIEDFRAKIERARADENQLSPASKGTYREYLGKLDLQYTKLLNTSKSRLRNLDQLYNFVNAATKELMWLNDKEEEEVNYDWSERNANMGAKKDNYSGLMRELELREKKVNDIQATGDRLIKDGHPGKKTVEAFTAGLQTQWSWILQLCCCIETHLKENTAYFQFFADVKEADERLKKMQDTMKKKYMCDRSTTATRLEDLLQDAVEEREQVNEFKNDIANLNKRAKSVIQLKPRDPTCPFRGKLPIQAVCDFKQMEITMHKGDECALINNSQPSRWKVLNRSGDEAVVPSICFLVPPVNKEAVESVSGLEAGHQQTVILWQKLHADLRALLSWQYLMKDIQLIRSWNITMFKTMKPDEYRLILRNLQLHYQDFLKDREESKLFNSSDNMQIERDYKETTQHFDNLLRTLEKGAAVRAQ----GEQDESVCKSYITQIKNLRLQIEDCESRTVARIRQPVDKDPLRDCIQKTADQKKVHVELDGIKKNLNKVSEKAEEVLSSADQSS-APVLRSELDITLQKMDQTYNLSSIYLEKLKTIEVVIRNTQGAEDVVKKYENRLREVHTVPTNVQEVENYCSELKTMRVDAEKQRPVFDDMEGELAKASAVSQRMVQIHTERDAELEHYRQMLGSLQDRWRAVFAQMDLRQRELEQLGRQLGYYRESYDWLIRWIADAKQRQEKIQAVPIIDSKTLKEQLAQEKKLLEEIEKNKDKVDECQKYAKNYIDTIKDYELQLVAYKAQVEPLTSPLKKTKMESASDNIIQEYVTLRTRYSELMTLTSQYIKFITDTQRRLEDEEKAAEKLKAEERKKMAEMQAELDKQKQLAEAHAKAIAKAEKEAQELKLMMQEEVSKREFVAVDAERQKQNIQLELHELKNLSEQQIKSKSQQVEEALQSRVKIEEEIRIIRLQLETTMKQKSTAQEELMQLRSKAAEAERLRKAAQEEAEKLRKQVNEETQKKRIAEEELKLKSEAEKEAARQKQKALDDLDKLKMEVDEAERHMKQAEIEKERQIKLAQDAAQKSASAELQSKRMSFVEKTSKLEESLREKHGTVIQLQEEAERLKKQQEEADKAREDAEKELEKWRQKANEALRLRLQAEEEAHKKTLAQEDAEKQKDEAEREAKKRAKAEESALKQKDMAEQELERQRKLAESTAQQKLSAEHELIRLRADFDHAEQQRSLLEDELYRLKSEVSAAEQQRKQLEDELSKVRSEMEVLLQLKSKAEKDSMSTTEKSKQLLEAEAGKLRDLADEAAKLRAIAEEAKRQRQVAEEEAARQRAEAERILKEKLAAINEATRLKTEAEIALKEKEAENERLRRKADDEAYQRKALEDQASQHKQDIEQKINQLKKSSEMELDRQKTIVDETLKQKRIVEEEIRILKLNFEKASSGKLDLELELNKLKNIADETQQSRLRAEEEAEKLRKLALEEENRRREAEEKLKKITAAEQEAARQRQAAQDEVERLKKKADEARKQKEDADKEAERQIYAAKEAAEKAITAEQQVQSVLVQQKEDSLVQ---------KKLKEEFEKAKRLAQEAEKAKEKAEKEAALLRQQAEDAERQRQTAEVEATNQAKAQEEAERLRKDAELEAEKRAQAEAAALKQKQIADEEMARHKKHAEQTLKQKSQVEQELAKVKLRLDETDKQKSVLDEELHRLKDEVGDAVKQKAQVEEELFKVRIQMEELIKLKLRIEQENQRLIQKDKDNTQKFLAEEAENMKKLAEEAARLSIEAQETARMRHIAETDLAEQRALAEKMLKEKMQAIQEASKLRAEAEMLQRQKDLAQEQAQRLLEDKQLMQQRLKEETEGFQKSLEAERRRQLDIAAEAERLRLQVSQLSDAQSRAEDEAKRFKKQADDISARLHETELSTKERMTVVEKLEIQRLSSTREADDLRKAIADLENEKAKLKKDAEDLQKKSKEMVNAQQEQIKQEKTILQQTFMSEKEMLLKKEKQIEDEKKRLESQFEEEVRKSKALKDEQERQRKQMEDEKIKLKASMDAALIKQKEAEKEMFNKQKEMQELERKKLEQERMLAEENQQLREKLQQLEVAQKI--TQEIHIQTD---------------CKKVLNGQ-SIEVDGTQGYPGLSFDGIREKVPASRLFDIGLLSKVDYDRLQSGGTTVQELSKTDKLKTILRGNNCISGLLVHP-NQKMPIYQAIKEKKIAPGTGLVLLEAQAASGYIIDPIKNKKLSVNEAVKEGLIGPELHNKMLSAEKAVTGYKDPYTEAKISLFEALKKDLIGQDHAIRLLDAQIATGGIIDPINSHRVPNEIAYKQGQFDAATNKILQNPTDDMKGFYDPNTEENLTYSQLMKRCVADPETGLPLLPISEEAAQN-ARIFTDEETRDVFDKTTVSVPFGRFKGKTVTIWEIINSEYFTEDQKKDLIRQYKTGRITVEKIIRIVLTVAEEKEKKNEIAFDGLRSPVPAAKLLESKVIDKDLYNKLQKGQLLVKDVSEMEHVRNALKGTNCIAGVIVDSTKQTMSFYDAMKSDTMRPGPALHLLEAQAATGYIIDPIKNQKLTVDEAVKAGVVGPELHEKLLSAERAVTGYKDPFAGKTVSLFEAMKKDLILKDQGIRLLDAQLATGGIIDPVESHRVPHDVACMRGCFDDATQKFLSSATDEVKGYFDPNTQENVTYLQLYKRCVTDKKTGLKLLPLSEQAINAREEMKYTDAQTKDAMTQATVEVQSGPFKGRKVTIWELINSDYLTEEQRIDLIRQYRSGKMTIEKITKILIVIVTEKDAKKQEEGCFKGLRAPVPAKSLFDSKIIDKPTYDLLEQGKKTPKEVSKDNSVNKYLQGSESIAGVYLEPTKEKVSIYQAMKKKFLRQNTGIALLEAQAATGFIVDPSRNECLSVDDAVKAGIVGPELHEKLLSAEKAVTGYKDPFTGNKISLYQAMDKDLVLKEHAMPLLEAQLATGGIIDPVNSHRLPVETAIQRGYVSKQLASSIAES----KYFSDPASDENISYKQLKDKCITEPDTGLNLLKLSKPQAPTVVEKTYLYSEEQTQSDLSTTQIDLPIE-GQG--SMSLWDVMNSNLLPEEQRAQLLEEYRSGNITKERMIIIIIEILEQREVIKGGNFQTGGTRRRQITIEDLYNARIIDLETFNMLKKEKKTMRDVMEMQSVKRYLYGTGSVAGVVTD-SNSKISIYQAMKREILKPEIAIGLLEAQAATGFIVDPVRNEMLTVDEAVRKGVVGPEFHDKLLSAERAVTGYKDPYSGKVISLFQAMKKGLVPEDYALRLLEAQTATGGIVDPEYNFHLPTEIATQRGYINKETNEKLSD---EVQGYVDPLTDEKMSYAQLLKRCKVDKD-GLHLLSLADRR-LLFRGLRKEITIEELIRSKIIDEQTVSELNEGRLTVEEVSNRLRKYLQGSSCISGVFVESTKDRLSIYQAMKKNMIRPGTAFELLEAQAATGYIIDPIKNLKLTVNEAVKMGIVGPEFKDKLLSAERAVTGYRDPYTGKMISLFQAMKKGLILRDHGIRLLEAQIATGGIIDPEESHRLPVEMAYNRGFFDEEMNEILNDPSDDTKGFFDPNTEENLTYLQLMERCIVDPDTGLVLLLLKEKKRERKTSSKSSVRKRRVVIVDPDSGKEMSVYEAYRKGLIDHQTYLELSEQECEWEEITMTSSEGVEKSILIDRRSGRQYDIDDAIAKGLIDQSAIDQYRSGTLSITEFADMLSGNMSGIRSRSSSFGSTSSYPMSPIPSIKTPASIWNDPTEETGPVAGILDTDSLEKVSVTEAIRRNVVDSITGQRLLEAQACTGGIIDPSTGEKFSVAEATEKGLIDKIMVDRLNLAQKAFHGFEDPRTKVKMSAAQALKKGWLYYEAGQRFLEVQYLTGGLIEPETEGRISLEEAIRKGAIDGRTAQKLRDVNAYTKYLTCPKTKLKISYKDAMDRSMVEEGSGIRLLEASSTSSKGLYSPYNVSGAASASGSRSGSRTGSRSGSRRGSFDATGSGFSMNFSSSSFTSSSYSRRF---------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : . :* : : . . : :.. : .. .: . . :: . :* : : . : . . ..:. :* .. .. . :: . . :. :*. .:.: .* ********** ********:* :***:.*********************::****: ****************:*:*********************************::* ****.***:**:******:******:**:*:******:*****:*******:*.* ***: *******:***:***::**::***************:************:**.*****..:**.::***:****** :** :* **:***. ****:****:**:*:** ******* ***.**:**.*** :::*:*.******:*:**.***:*******:*********: ** ****** **:**:*:***:*:***** *.::***:*:*** :** *:: ::* **:**:.*** ****** ****** *.*************** :*:::*****: . ::..: . . **:*:: **:* :***:******:*:: **** ***:**:*******:**:**:*: **:*** **.**:*.::*:**: **:*****:***.:**:***.*:.*: ** **********:******.:***:**:** ***:.**.***:** :**:::::* :**:*:::.**.: *:*:* *.*******:********:*****:******:**:**: :::*:::::::** ***: *.********** :*:**:**:* .: .* :***:::*****.*: *.:*::*: ****:**:*:*:****:* *:. :** :*** . *..**.***:**:*** *:** : : *:. :* : **::**.*:::**:** * :*: **.**.: *:*:: :* * *:.*: *** **:* ::: *...*.: *..* . ::*:::**:::*: * *:** *: *:::*::**::* **:*** *:* :**:* : * *: ::*:*.:.*::*: *.: :: ::* **: .: *. **.****:::* *:::. .**::**:*****.:***.*****:::. :*::*:*.: **.. *:* :.*:.:* :** ::..*: :. ** * *.:*: * * ***.*:*::*: : .* :**:**:** ::*****: *.**: **** * * *: **: **::::*:*: ..: :*** **: ******:: :**::**::** **::********::*** :**::** **.*::*.*:.:***** ***:**** **:******* :* **:::**: **: : ***:::**::* *:**:****:**:* *:** **.**: *::** :*: .***:::**:.** **:.*: ** :*::*::*.* * ** :*****:::*****:* :*:. *: ** **::* :*: :. ******:**:** :*:*:** ** ** : :** :**::*::**: *::::::.:**** : *** *: **:::. :.*:::* .:*:** . *::**.:*:::: * **:****: :** **::***:**:*** *: ************** *::*: ** :*****:**:***::*.**** *::*:: ** ** .**:::* **:*:*:**:*******: ::.*:** :*::** **: :. :* :::::** ** *** ***:** *::**::: *.:***** **:**.::*:**:**::**::****:::*::***:********: :* ***:**.********************:**:* *::*.:**: **:**: ** **::: **:*:*: **:*** :*::**:*:: ***** ** .****::** :***** :::. *::* :*: ** ** : *:** ***.:*:*** :::: ***:*****::.* :** ** .:**:: :* *::*: :*: .:***:* **::.: . ***.::.: * .:*: * * *:: *:***:*: :**:*** :::.*:*** :::** :* :*:** **:***:** ** :**:** ***: ** ** ** ::** **:**:**:.**:**..::::*:***:**.:** **:*** *. :* :*::***:** .*::***:* *** :** **: *: :*****:::* ****:**::*******.: ***:**:*::** ***:** ******:** **:***::*:**** **:**: ** :*::* *: * *:* :**:***::*****:***:::****:*:::::::* **::**::*::*:***::* :*:.** *.*: *:*:.**:** .* ::*: *::***:**.** **:::* ** :*:** ..****: **. **::*::**: **::*: **:** :**. *::** *:: *: **:**:: **:*: .* ::*: * :*:***: : **:*:* **::: :**.:*****:.***:** *: :: ::. .: : * : ** : : . : :*:*:*.**.*.:* : *:** : ::* .* *** **:: :.: *:* ..*.*:::.. *:*:.:* *:: : :: .*.::*********:::**::*::*:*.*:**:*::***** *:****:****:***:* **:*:*::*.** .::.::**:.* ****:***::**:** ::* :* :* .::* .*. * *.* ****.:.*** :*:.:* *.***: ***::::**:. ::* *::***.*:.::.***:*:*:******:******* :*::**::*::**:*******:*::**.*::*.* . .*:***: ***::**:: **.::::::*:.*: :::*:* : *:.**:*: **** ::.: :.:*:*:*:: : : . *: ******.**.**** .. :*******::*:****:********:** **:**::*::****:*::*.** ::**:***:***:****:** :*:*:. *:* ** ::. .: *: . * **.* * .** :* :** .*: *** *:****:* .::: :: *::: : :: **: * **** :*:**:*.*:*:* *** :::**:*:**:*:**: **:* * * : :*:. *.***.****..*: : ::.: :: : :**.. ::* **. **** .:**:::: :***::**:**:: :* *. *********:::** **: : *.:*****:****:**:***********:**::*..*** ***.* ***::*.: **:**:*********:***:* :.* :***..::: : :. * * ** ..**::* ** ::*: :*: *: ** * .: .*.: :*:**::: : ****:* . ::**:**:*:::**::: :*: ::::*.:*****:******:*: *:*: : . **::* ::*:.****.***:*:::: .: :*:.:* *. **:***:::** . .::****:*: ::..::. **********::***:.* **********:****:**:***********:***: : ********* *:* : *::**:** ****::**. *:** ::* ****:**:* :::*: :*. ::** ***::**:.**:**: *. * ** *:* * * *:****:** ***:**:::*: * * ** ::*:::: *:*:*:* *.*:****::**:***:****** :******************:*****.**:.*:***:**:*******************:***:**:*************:****************************:**:**:****** **.***************************:.*.:*** ** **************************::********************:**:********** :**:** **::***********.***:*.***:**:****:*************** .*:******.**:****:*. . :* : *.***************::*****:***::**:**.*******************.***:*.*::* :***:*******:******: ********.**********************************:. **:.*:**:::*::*.*********..*:*****************:****:***:*:*****:: *:** ****.:**:.*::***:*******:**************** **** ::.:.*.**: ", "identical_positions": 2482, "similar_positions": 1418, "identity": "41.3%" }, { "cls_id": "homologset.agr.MGI:1277962", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZNA8-1", "uniprot_id": "D3ZNA8_RAT", "id": "D3ZNA8-1", "name": "Checkpoint protein", "aln": "MKFRAKIVDLACLNHFTRVSNMIAKLAKTCTLRISPEKLNFILCDKLASGG-VSMWCELEQENFFSEFQMEGVSEENNEIYLELTSENLARALKTAQNA--RALKIKLTNKHFPCLTVSVELLSSSS-SSRIVVHDIPIKVIPRRLWKDLQEPSIPESDVSIYLPALKTMKSVVDKMRNISNHLVIEANLKGELNLKIETESVCVTTHFKDLENPLLPSDSVSQNRHPEDMAKVHIDIRKLLQLLAGQQVAPTKAVCNIVNNRTIHFDL-LLEDVSLQYFIPALS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BQY8-1", "uniprot_id": "HUS1_MOUSE", "id": "Q8BQY8-1", "name": "Checkpoint protein HUS1", "aln": "MKFRAKIVDLACLNHFTRVSNMIAKLAKTCTLRISPEKLNFILCDKLASGG-VSMWCELEQENFFSEFQMEGVSEENNEIYLELTSENLSRALKTAQNS--RALKIKLTNKHFPCLTVSVELVSSSS-SSRIVVHDIPIKVLPRRLWKDLQEPSIPDCDVSICLPALKMMKSVVEKMRNISNQLVIEANLKGELNLKIETELVCVTTHFKDLENPLLPSDSVSQNRHPEDMAKVHIDIKKLLQFLAGQQVTPTKAVCNIVNNRTVHFDL-LLEDVSLQYFIPALS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60921-1", "uniprot_id": "HUS1_HUMAN", "id": "O60921-1", "name": "Checkpoint protein HUS1", "aln": "MKFRAKIVDGACLNHFTRISNMIAKLAKTCTLRISPDKLNFILCDKLANGG-VSMWCELEQENFFNEFQMEGVSAENNEIYLELTSENLSRALKTAQNA--RALKIKLTNKHFPCLTVSVELLSMSS-SSRIVTHDIPIKVIPRKLWKDLQEPVVPDPDVSIYLPVLKTMKSVVEKMKNISNHLVIEANLDGELNLKIETELVCVTTHFKDLGNPPLASESTHEDRNVEHMAEVHIDIRKLLQFLAGQQVNPTKALCNIVNNKMVHFDL-LHEDVSLQYFIPALS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VN60-1", "uniprot_id": "HUS1_DROME", "id": "Q9VN60-1", "name": "Checkpoint protein Hus1-like", "aln": "MKFRALMQDPLYMKEFQAIVATLTKLAKDCVMILGSRQMHFIVNEDQSSAASPLVWAGITAEEYFPEYRMEAAHPDQEYIVLGVSSANLGRALSVLRGGGVNSCKLKLQRIQFPCISVIASVLTSSSTEAREVVHDVPVTIIPGSDWSAYVVPRVPNSQLALGLPSLRLLKSLIDKLKNISPSLEFQVNVDGELNVIATSEMSTVTSRFQKLLIRTVSGS--------QQEASCSVDSRKASAFFGALQLPNEELTIGIDREHSIHLQIDVRQDVVLHSILPAVCM", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***** : * ::.* : ::**** *.: :.. :::**: :. :... :*. : *::* *::**.. ::: * * ::* **.***.. :.. .: *:** . :***::* ..::: ** .:* *.**:*:.::* *. * :*: :::: ** *: :**:::*::*** * ::.*:.****: :* **::*:.* :... :. *. :* :* ::.. *: : .* .:: :*::: : :** *: ::**:. ", "identical_positions": 77, "similar_positions": 117, "identity": "26.92%" }, { "cls_id": "homologset.agr.MGI:1277964", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P07896-1", "uniprot_id": "ECHP_RAT", "id": "P07896-1", "name": "Peroxisomal bifunctional enzyme", "aln": "MAEYLRLPHSLAMIRLCNPPVNAVSPTVIREVRNGLQKAGSDHTVKAIVICGANGNFCAGADIHGFSAFTP-GLALGSLVDEIQRYQKPVLAAIQGVALGGGLELALGCHYRIANAKARVGLPEVTLGILPGARGTQLLPRVVGVPVALDLITSGKYLSADEALRLGILDAVVKSDPVEEAIKFAQKIIDKPIEPRRIFNKPVPSLPNMDSVFAEAIAKVRKQYPGVLAPETCVRSIQASVKHPYEVGIKEEEKLFMYLRASGQAKALQYAFFAEKSANKWSTPSGASWKTASAQPVSSVGVLGLGTMGRGIAISFARVGISVVAVESDPKQLDAAKKIITFTLEKEASRAHQNGQASAKPKLRFSSSTKELSTVDLVVEAVFEDMNLKKKVFAELSALCKPGAFLCTNTSALNVDDIASSTDRPQLVIGTHFFSPAHVMRLLEVIPSRYSSPTTIATVMSLSKKIGKIGVVVGNCYGFVGNRMLAPYYNQGFFLLEEGSKPEDVDGVLEEFGFKMGPFRVSDLAGLDVGWKIRKGQGLTGPSLPPGTPVRKRGNSRYSPLGDMLCEAGRFGQKTGKGWYQYDKPLGRIHKPDPWLSTFLSQYREVHHIEQRTISKEEILERCLYSLINEAFRILEEGMAARPEHIDVIYLHGYGWPRHKGGPMFYAASVGLPTVLEKLQKYYRQNPDIPQLEPSDYLRRLVAQGSPPLKEWQSLAGPHGSKL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DBM2-1", "uniprot_id": "ECHP_MOUSE", "id": "Q9DBM2-1", "name": "Peroxisomal bifunctional enzyme", "aln": "MAEYLRLPHSLAMIRLCNPPVNAISPTVITEVRNGLQKASLDHTVRAIVICGANDNFCAGADIHGFKSPT--GLTLGSLVDEIQRYQKPVVAAIQGVALGGGLELALGCHYRIANAKARVGFPEVMLGILPGARGTQLLPRVVGVPVALDLITSGRHISTDEALKLGILDVVVKSDPVEEAIKFAQTVIGKPIEPRRILNKPVPSLPNMDSVFAEAIAKVRKQYPGRLAPETCVRSVQASVKHPYEVAIKEEAKLFMYLRGSGQARALQYAFFAEKSANKWSTPSGASWKTASAQPVSSVGVLGLGTMGRGIAISFARVGIPVVAVESDPKQLDTAKKIITSTLEKEAS---KSGQASAKPNLRFSSSTKELSSVDLVIEAVFEDMNLKKKVFAELSALCKPGAFLCTNTSALDVDDIASSTDRPQLVIGTHFFSPAHIMRLLEVIPSRYSSPTTIATVMSLSKRIGKIGVVVGNCYGFVGNRMLAPYYNQGYFLIEEGSKPEDVDGVLEEFGFRMGPFRVSDLAGLDVGWKVRKGQGLTGPSLPPGTPTRKRGNTRYSPIADMLCEAGRFGQKTGKGWYQYDKPLGRIHKPDPWLSEFLSQYRETHHIKQRSISKEEILERCLYSLINEAFRILEEGMAASPEHIDVIYLHGYGWPRHVGGPMYYAASVGLPTVLEKLQKYYRQNPDIPQLEPSDYLRRLVAQGSPPLKEWQSLAGPHSSKL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q08426-1", "uniprot_id": "ECHP_HUMAN", "id": "Q08426-1", "name": "Peroxisomal bifunctional enzyme", "aln": "MAEYTRLHNALALIRLRNPPVNAISTTLLRDIKEGLQKAVIDHTIKAIVICGAEGKFSAGADIRGFSAPRTFGLTLGHVVDEIQRNEKPVVAAIQGMAFGGGLELALGCHYRIAHAEAQVGLPEVTLGLLPGARGTQLLPRLTGVPAALDLITSGRRILADEALKLGILDKVVNSDPVEEAIRFAQRVSDQPLESRRLCNKPIQSLPNMDSIFSEALLKMRRQHPGCLAQEACVRAVQAAVQYPYEVGIKKEEELFLYLLQSGQARALQYAFFAERKANKWSTPSGASWKTASARPVSSVGVVGLGTMGRGIVISFARARIPVIAVDSDKNQLATANKMITSVLEKEASKMQQSGHPWSGPKPRLTSSVKELGGVDLVIEAVFEEMSLKKQVFAELSAVCKPEAFLCTNTSALDVDEIASSTDRPHLVIGTHFFSPAHVMKLLEVIPSQYSSPTTIATVMNLSKKIKKIGVVVGNCFGFVGNRMLNPYYNQAYFLLEEGSKPEEVDQVLEEFGFKMGPFRVSDLAGLDVGWKSRKGQGLTGPTLLPGTPARKRGNRRYCPIPDVLCELGRFGQKTGKGWYQYDKPLGRIHKPDPWLSKFLSRYRKTHHIEPRTISQDEILERCLYSLINEAFRILGEGIAASPEHIDVVYLHGYGWPRHKGGPMFYASTVGLPTVLEKLQKYYRQNPDIPQLEPSDYLKKLASQGNPPLKEWQSLAGSPSSKL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NYL3-1", "uniprot_id": "ECHP_DANRE", "id": "Q6NYL3-1", "name": "Peroxisomal bifunctional enzyme", "aln": "MARYELVKRSVALITLTNPPVNALSSAVRHAISKTMERALSDPKVTAVVICGENGRFCGGADIREFAGPLR-GPPLVPLLDAIEAGEKPVVAAIEGVALGGGFELALVCHYRIAHYKARLGLPEVTLGILPAAGGTQRLPRLIGIPAALELITTGRHVSAQEALKLGMVDQVTEQNTCEVALEFALKAVGKPLSSRRLSMLTTPCPPGLDGIFEAATMQVQKKARGVMAPLACVQAVRAAT-LPYSEGIKREGELMATLFSSGQAQALQYSFFAQRTAEKWTLPSGAQWNNSKPREIQSAAVIGLGTMGRGIVVSLARVGISVIAVESEKKLLETGRQMVIGMLERDAK---RRGVSASLNLLKFSLSLQDLKDVDLVIEAVFEDMALKKQIFRELSRVCRPATLLCSNTSGLDVDALADVTDRPQLVAGMHFFSPAHVMKLLEVVCGPRSSKEAIATAMSLGKRMGKVSVAVGNCPGFVGNRMLMPYLEQATFLLEEGATPQQIDKALEDFGFAMGVFRMSDLAGLDVGWRVRKESGLTGPDVDPKDPPRRRQGRKYCPIPDMVCQQGRFGQKTGRGWYMYDKPGDTNAKPDPLIQNLLETYRSRYGIQPRKITDQEIIERCLFALANEGFRILKDKIAGQPEDIDVIYLFGYGFPRHRGGPMFYASMVGLERVLERLEYYHHALPDVPHLEPSPLLKKLVARGSPPIQKWREHIKSMHSHL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.* : .::*:* * ******:*.:: : : :::* * .: *:**** :..*..****: * . * .* ::* *: :***:***:*:*:***:**** ******: :*::*:*** **:**.* *** ***: *:*.**:***:*: : ::***:**::* *.:.:. * *:.** .:*:..**: . . *.:*.:* * ::::: * :* :**::::*:. **. .**.* :*: * ****:****:***::.*:**: ****.*:.:..: :.*..*:*********.:*:**. *.*:**:*: : * :..::: **::*. : * . : ::: * ::* ****:*****:* ***::* *** :*:* ::**:***.*:** :*. ****:** * *******:*:****: . ** :***.*.*.*:: *:.*.**** ******** ** :*. **:***:.*:::* .**:*** ** **:**********: ** .***** : * * *:* . :*.*: *::*: ********:*** **** . **** :. :*. **. : *: *.*:.:**:****::* **.**** : :*. **.***:**.***:*** ****:**: *** ***:*: *:: **:*:**** *::*.::*.**:::*:. . *:*", "identical_positions": 344, "similar_positions": 230, "identity": "47.58%" }, { "cls_id": "homologset.agr.MGI:1277968", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P85125-1", "uniprot_id": "CAVN1_RAT", "id": "P85125-1", "name": "Caveolae-associated protein 1", "aln": "MEDVTLHIVERPYSGYPDASSEGPEPTPGEARAT---EEPSGTGSDE-----------LIK----------SDQVNGVLVLSLLDKIIGAVDQIQLTQAQLEERQAEMEGAVQSIQGELSKLGKAHATTSNTVSKLLEKVRKVSVNVKTVRGSLERQAGQIKKLEVNEAELLRRRNFKVMIYQDEVKLPAKLSVSKSLKESEALPEKEGDELGEGERPEEDAAAIELSSDEAVEVEEVIEESRAERIKRSGLRRVDDFKKAFSKEKMEKTKVRTRENLEKTRLKTKENLEKTRH-----------TLEKRMNKLGTRLVP-VERREKLKTSRDKLRKSFTPDHVVYARSKTAVYKVPPFTFHVKKIREGEVEVLKATEMVEVGPDDDEVGAERGAETDLLRGSSPDVHTLLEITEESDAVLVDKSDSD-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O54724-1", "uniprot_id": "CAVN1_MOUSE", "id": "O54724-1", "name": "Caveolae-associated protein 1", "aln": "MEDVTLHIVERPYSGFPDASSEGPEPTQGEARAT---EEPSGTGSDE-----------LIK----------SDQVNGVLVLSLLDKIIGAVDQIQLTQAQLEERQAEMEGAVQSIQGELSKLGKAHATTSNTVSKLLEKVRKVSVNVKTVRGSLERQAGQIKKLEVNEAELLRRRNFKVMIYQDEVKLPAKLSVSKSLKESEALPEKEGDELGEGERPEDDTAAIELSSDEAVEVEEVIEESRAERIKRSGLRRVDDFKKAFSKEKMEKTKVRTRENLEKTRLKTKENLEKTRH-----------TLEKRMNKLGTRLVP-VERREKLKTSRDKLRKSFTPDHVVYARSKTAVYKVPPFTFHVKKIREGEVEVLKATEMVEVGPEDDEVGAERGEATDLLRGSSPDVHTLLEITEESDAVLVDKSDSD-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6NZI2-1", "uniprot_id": "CAVN1_HUMAN", "id": "Q6NZI2-1", "name": "Caveolae-associated protein 1", "aln": "MEDPTLYIVERPLPGYPDA--EAPEPSSAGAQAA---EEPSGAGSEE-----------LIK----------SDQVNGVLVLSLLDKIIGAVDQIQLTQAQLEERQAEMEGAVQSIQGELSKLGKAHATTSNTVSKLLEKVRKVSVNVKTVRGSLERQAGQIKKLEVNEAELLRRRNFKVMIYQDEVKLPAKLSISKSLKESEALPEKEGEELGEGERPEEDAAALELSSDEAVEVEEVIEESRAERIKRSGLRRVDDFKKAFSKEKMEKTKVRTRENLEKTRLKTKENLEKTRH-----------TLEKRMNKLGTRLVP-AERREKLKTSRDKLRKSFTPDHVVYARSKTAVYKVPPFTFHVKKIREGQVEVLKATEMVEVGADDDEGGAERGEAGDLRRGSSPDVHALLEITEESDAVLVDKSDSD-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F0K3-1", "uniprot_id": "E7F0K3_DANRE", "id": "E7F0K3-1", "name": "", "aln": "MADTDFKLERAIFAEVSDDDEEVALVTSAAKPATSLKEFKSRRGDDEDDDDDSEKEVDLVLGPGLDGGDAEKSDATGILVLALLDKIIGVVDKIQQTQTSLEAKQEVMEKNMSSIQTELAKLAKSHVGTAGTVNKLLDKVRKVNVNVKSVRADLEKQVGQIKKLENNEQELLKRKNIKVLIIPEKGK-PVKVSKKPAGEEGEQVLSEGGEEEHASE-------------GEEVEVEETIEESRAERIKRSGLQKVDELKKAFSKEQMQKTRQKTKENLEKTRMRTKENLEKTRQRTRENLEKTKKSLGKKMGKFGTKLTPNTERREKIRSSREKMKKSLNPDHTVYARSKSTTYRVPPFTFHVKKIRGGEAEPTPEPEEEDEEQKEEEEEGDLVEEAELVSLDGPEMEAADRSRLAFQETVRPRETAGL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * : : . . .* * . : . *: * * *.:* *: ..:..*:***:*******.**:** **:.** :* ** :.*** **:**.*:*. *:.**.***:*****.****:**..**:*.******* ** ***:*:*:**:* :: * *.*:* . : :*.* : .: *:* .* .* *****.**************::**::*******:*:**: :*:*******::*********: :* *:*.*:**:*.* .*****:::**:*::**:.***.******::.*:************ *:.* .* : .::* .: :* ..*::.: . : .: :. :. ", "identical_positions": 182, "similar_positions": 115, "identity": "42.42%" }, { "cls_id": "homologset.agr.MGI:1277969", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XIU2-1", "uniprot_id": "ZN143_RAT", "id": "Q5XIU2-1", "name": "Zinc finger protein 143", "aln": "MLLAQINRDSQGMTEFPGGGMEAQHVTLCLTEAVTVADGDNLENMEGVSLQAVTLADGSTAYIQHNSK----DGRLIDGQVIQLEDGSAAYVQHVPIPKS---------------TGDSLRLEDGQAVQLEDGTTAFIHHTSKDSYDQSSLQAVQLEDGTTAYIHHAVQVPQPDTILAIQADGTVAGLHTGDATIDPDTISALEQYAAKVSIDGSEGVTSTGLIGENEQE-KKMQIVLQGHATRVTPKSQQSGEKAFRCKYDGCGKLYTTAHHLKVHERSHTGDRPYQCEHSGCGKAFATGYGLKSHFRTHTGEKPYRCSEDNCTKSFKTSGDLQKHIRTHTGERPFKCPIEGCGRSFTTSNIRKVHIRTHTGERPYYCTEPGCGRAFASATNYKNHVRIHTGEKPYVCTVPGCDKRFTEYSSLYKHHVVHTHSKPYNCNHCGKTYKQISTLAMHKRTAHNDTEPIEEEQEAFFEPPPGQGDDVLKGSQITYVTGVEGEDIVSTQVATVTQSGLSQQVTLISQDGTQHVNISQADMQAIGNTITMVTQDGTPITVPTHDAVISSAGTHSVAMVTAEGTEGQQVAIVAQDLAAFHAASSEMGHQPHSHHLVTTETRPLTLVATSNGTQIAVQLGEQPSLEEAIRIASRIQQGETPGLDD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70230-1", "uniprot_id": "ZN143_MOUSE", "id": "O70230-1", "name": "Zinc finger protein 143", "aln": "MLLAQINRDSQGMTEFPGGGMEAQHVTLCLTEAVTVADGDNLENMEGVSLQAVTLADGSTAYIQHNSK----DGRLIDGQVIQLEDGSAAYVQHVPIPKS---------------TGDSLRLEDGQAVQLEDGTTAFIHHTSKDSYDQSSLQAVQLEDGTTAYIHHAVQVPQSDTILAIQADGTVAGLHTGDATIDPDTISALEQYAAKVSIDGSDGVTSTGMIGENEQE-KKMQIVLQGHATRVTPKSQQSGEKAFRCKYDGCGKLYTTAHHLKVHERSHTGDRPYQCEHSGCGKAFATGYGLKSHFRTHTGEKPYRCSEDNCTKSFKTSGDLQKHIRTHTGERPFKCPIEGCGRSFTTSNIRKVHIRTHTGERPYYCTEPGCGRAFASATNYKNHVRIHTGEKPYVCTVPGCDKRFTEYSSLYKHHVVHTHSKPYNCNHCGKTYKQISTLAMHKRTAHNDTEPIEEEQEAFFEPPPGQGDDVLKGSQITYVTGVDGEDIVSTQVATVTQSGLSQQVTLISQDGTQHVNISQADMQAIGNTITMVTQDGTPITVPTHDAVISSAGTHSVAMVTAEGTEGQQVAIVAQDLAAFHTASSEMGHQQHSHHLVTTETRPLTLVATSNGTQIAVQLGEQPSLEEAIRIASRIQQGETPGLDD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P52747-1", "uniprot_id": "ZN143_HUMAN", "id": "P52747-1", "name": "Zinc finger protein 143", "aln": "MLLAQINRDSQGMTEFPGGGMEAQHVTLCLTEAVTVADGDNLENMEGVSLQAVTLADGSTAYIQHNSK----DAKLIDGQVIQLEDGSAAYVQHVPIPKS---------------TGDSLRLEDGQAVQLEDGTTAFIHHTSKDSYDQSALQAVQLEDGTTAYIHHAVQVPQSDTILAIQADGTVAGLHTGDATIDPDTISALEQYAAKVSIDGSESVAGTGMIGENEQE-KKMQIVLQGHATRVTAKSQQSGEKAFRCEYDGCGKLYTTAHHLKVHERSHTGDRPYQCEHAGCGKAFATGYGLKSHVRTHTGEKPYRCSEDNCTKSFKTSGDLQKHIRTHTGERPFKCPFEGCGRSFTTSNIRKVHVRTHTGERPYYCTEPGCGRAFASATNYKNHVRIHTGEKPYVCTVPGCDKRFTEYSSLYKHHVVHTHSKPYNCNHCGKTYKQISTLAMHKRTAHNDTEPIEEEQEAFFEPPPGQGEDVLKGSQITYVTGVEGDDVVSTQVATVTQSGLSQQVTLISQDGTQHVNISQADMQAIGNTITMVTQDGTPITVPAHDAVISSAGTHSVAMVTAEGTEGEQVAIVAQDLAAFHTASSEMGHQQHSHHLVTTETRPLTLVATSNGTQIAVQLGEQPSLEEAIRIASRIQQGETPGLDD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LYE3-1", "uniprot_id": "Z143B_DANRE", "id": "Q1LYE3-1", "name": "Zinc finger protein 143B", "aln": "MLLAQVNRDTQGM-EFQSVDGDPQQVTLCLTEAVTVAD-DNIDGMDTVSLQAVTLVDGSTAYIQHSPKVSLTENKIMEGQVIQLEDGSAAYVQHLPMSKT---------------GGEGLRLEDGQAVQLEDGTTAYIHAP-KETYDQGGLQAVQLEDGTTAYIQH---MPQSNTILAIQADGTVADLQT-EGTIDAETISVLEQYSTKMEATECG----TGLIGRGDSDGVHMQIVLQGQDCR-SPRIQHVGEKAFRCEHEGCGKLYTTAHHLKVHERSHTGDKPYICDHLGCGKKFATGYGLKSHVRTHTGEKPYRCQELNCLKSFKTSGDLQKHTRTHTGEKPFKCPFEGCGRSFTTSNIRKVHIRTHTGERPYYCAEPNCGRAFASATNYKNHMRIHTGEKPYVCTVPGCDKRFTEYSSLYKHHVVHTPCKPYNCNHCGKTYKQISTLAMHKRTAHNDTEPIEEEQEGYFEPP----AEAIDDPGLMYTPSVVDDDSGSEQVSGSEIMG-QHHVALISQDGTQQV-LSQADMQAMGGTITMVTQEGTTITIPAHEAMLSSGGAHSVTMVSADGTEG-QVAIVTPDLAAYQTEEGEL-IQDQEQHEVSTSPHPVTLLATSNGTHIAVQLSDHPSLEEAIRIASRIQQGETPGMDD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q5U3T5-1", "uniprot_id": "Z143A_DANRE", "id": "Q5U3T5-1", "name": "Zinc finger protein 143A", "aln": "MLLAQINQS----ADFQHED-DSQEVTLCLTETVGIADCD--QSMDTVSLQAVTLSDGSTAYIPHNPQ----DNSIVEGQVIQLEDGSSAYVQHIAVPKADEPNNWMGSSVCDVVGNESLRLEDAQTVQLEDGTTAYIHHTTKDVYEPSTLQAVQLEDGSTAYIQHAVQVSQPNTILAIQANGTVADLHT-DAAIDQETMNALEQYTTKIEEIDSYTN--PELISNDPQGVVEMQIVLQGQGIR--RNVQSPGEKCFRCNYDGCGKLYTTANHLKVHERAHTGDKPYCCDLPGCGKKFATGYGLKSHIRTHTGEKPYRCQELDCKKSFKTSGDLQKHTRIHTGEKPFLCPFPGCGRSFTTSNICKVHVRTHTGEKPYHCPEPGCNRAFASATNYKNHIRIHTGERPYVCTVPGCDKRFTEYSSLYKHNVVHTPCKPYKCNHCGKTYKQISTLVMHKRSAHNDSEPIEEEMEGYFEPP----SEAIDDPSLSVSP-VKCEDSGPEMTSEISDVSEQQHVTLITQDG---------GSQAIGNAITMVTQDGSMITIPPTESLLASAEAHSVTVATEDGTER-QMAIMMPELTSRNTQDGLS-------------AHPITLLATSNGTQIAVQLSEQTSLEEALRIASSLQAEEAELAD-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*****:*:. :* . :.*.*******:* :** * :.*: ******** ******* *..: : :::**********:*****:.:.*: .:.*****.*:*********:** . *: *: . *********:****:* :.*.:*******:****.*:* :.:** :*:..****::*:. . . :*... . .*******: * . * ***.***:::*********:*******:****:** *: **** **********.***********.* :* ************ * ****:** **: *********** ***:******:**:*.**.*.************:******:**********************:**** .***:**************.****:****:****** *.:**** :.:... : . * :* . .: . .::*:**:*** . **:*.:******:*: **:*. :::::*. :***::.: :*** *:**: :*:: :: .. .:*:**:******:*****.::.*****:**** :* *: * ", "identical_positions": 358, "similar_positions": 154, "identity": "54.41%" }, { "cls_id": "homologset.agr.MGI:1277971", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q68G30-1", "uniprot_id": "KLC3_RAT", "id": "Q68G30-1", "name": "Kinesin light chain 3", "aln": "MSVQVAAPGSTGLGPERLNPEELVRQTRQVVQGLEALRAEHHSLAGHLAEALAGPGPVAGVELLEEKQQVVNHSLEAIELGLGEAQVLLALSAHVGVLEAEKQRLRAQARRLAQENTWLREELEETQRRLRASEEAVAQLEEEKSHLQFLGQLRQYDPPEESQRPDSPPRRDSLASLFPSEEEEKKG---PEAAGAAAAQQGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCRQALEDLERSSGHCHPDVATMLNILALVYRDQNKYKEATELLHDALQIREQTLGPEHPAVAATLNNLAVLYGKRGRYREAEPLCQRALEIREKVLGADHPDVAKQLNNLALLCQNQGKFQDVERHYARALSIYEALGGPQDPNVAKTKNNLASAYLKQNKYQQAEELYKEILS--QEALPAPLGAP-----QGGTAGEAQQQVLRRSSSFSKLR---ESIRRGSEKLVSRLR-------GESMAGAAGMKRAMSLNMLNVDGPRAAR---MQLSTQHLNEASRTLSAS---TQDLSPR-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91W40-1", "uniprot_id": "KLC3_MOUSE", "id": "Q91W40-1", "name": "Kinesin light chain 3", "aln": "MSVQVAAPGSTGLGPERLNPEELVRQTRQVVQGLEALRAEHHSLAGHLAEALAGPGPVAGVELLEEKQQVVNHSLEAIELGLGEAQVLLALSAHVSVLEAEKQRLRAQARRLAQENTWLREELEETQRRLRASEEAVAQLEEEKSHLQFLGQLRQYDPPEESQRPESPPRRDSLASLFPSEEEEKKG---PEAAGAAAAQQGGYEIPARLRTLHNLVIQYAGQGRYEVAVPLCRQALEDLERSSGHCHPDVATMLNILALVYRDQNKYKEATELLHDALQIREQTLGPEHPAVAATLNNLAVLYGKRGRYREAEPLCQRALEIREKVLGADHPDVAKQLNNLALLCQNQGKFQDVERHYARALSIYEALGGPQDPNVAKTKNNLASAYLKQNKYQQAEELYKEILS--QEALPAPLGAP-----QGGTAGDTQQQVLRRSSSFSKLR---ESIRRGSEKLVSRLR-------GEGMAGAAGMKRAMSLNMLNVDGPRAARTQLSQLSTRHLSEAPRTLSIS---TQDLSPR-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6P597-1", "uniprot_id": "KLC3_HUMAN", "id": "Q6P597-1", "name": "Kinesin light chain 3", "aln": "MSVQVAAPGSAGLGPERLSPEELVRQTRQVVQGLEALRAEHHGLAGHLAEALAGQGPAAGLEMLEEKQQVVSHSLEAIELGLGEAQVLLALSAHVGALEAEKQRLRSQARRLAQENVWLREELEETQRRLRASEESVAQLEEEKRHLEFLGQLRQYDPPAESQQSESPPRRDSLASLFPSEEEERKG---PEAAGAAAAQQGGYEIPARLRTLHNLVIQYAGQGRYEVAVPLCRQALEDLERSSGHCHPDVATMLNILALVYRDQNKYKEATDLLHDALQIREQTLGPEHPAVAATLNNLAVLYGKRGRYREAEPLCQRALEIREKVLGADHPDVAKQLNNLALLCQNQGKFEDVERHYARALSIYEALGGPHDPNVAKTKNNLASAYLKQNKYQQAEELYKEILH--KEDLPAPLGAP-----NTGTAGDAEQ-ALRRSSSLSKIR---ESIRRGSEKLVSRLR-------GEAAAGAAGMKRAMSLNTLNVDAPRAPG---TQFPSWHLDKAPRTLSAS---TQDLSPH-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P46824-1", "uniprot_id": "KLC_DROME", "id": "P46824-1", "name": "Kinesin light chain", "aln": "--------------MTQMSQDEIITNTKTVLQGLEALRVEHVSIMNGIAEVQKD----------NEKSDMLRKNIENIELGLSEAQVMMALTSHLQNIEAEKHKLKTQVRRLHQENAWLRDELANTQQKFQASEQLVAQLEEEKKHLEFMASVKKYDENQEQDDACDKSRTDPVVELFPDEENEDRHNMSPTPPSQFANQTSGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLERTSGHDHPDVATMLNILALVYRDQNKYKEAANLLNDALSIRGKTLGENHPAVAATLNNLAVLYGKRGKYKDAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYDEVEKYYQRALDIYESKLGPDDPNVAKTKNNLAGCYLKQGRYTEAEILYKQVLTRAHEREFGAIDSKNKPIWQVAEEREEHKFDNRENTPYGEYGGWHKAAKVDSPTVTTTLKNLGALYRRQGMFEAAETLEDCAMRSKKEAYDLAKQTKLSQLLTSNEKRRSKAIKEDLDFSEEKNAKP", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::. :*:: :*: *:*******.** .: . :**. . :**.::: :.:* *****.****::**::*: :****::*::*.*** ***.***:** :**::::***: ******** **:*:..:::** *.: . . .* *.:..***.**:* : * ... * * .*******************.***********:********:*** ************************::**:***.** :*** :*******************:*::*****:*********** *********************:::**::* ***.***: **.************..****.:* :** ***::* :* ..:.: : . : .: *..:. .: :: : .* .:.: *: :. ** . ::. : * *: : : .. .:::. . ::: ..: ", "identical_positions": 250, "similar_positions": 145, "identity": "46.99%" }, { "cls_id": "homologset.agr.MGI:1277973", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97770-1", "uniprot_id": "THUM3_MOUSE", "id": "P97770-1", "name": "tRNA (guanine(6)-N(2))-methyltransferase THUMP3", "aln": "--------------------------------------MSCDTQEATRECLGMNLDGNKEPVSLVESGVRSESEHLQVTIGATVPTGFEQTAAGEVREKLKSACRISKDRGKIYFDIAVESLAQVHCLRSVDNLFVVVQEFKDYQFKDTKEEVLRDFEELAGKLPWSDPLKVWQINTTFKKKKAKRRKANQSAGKEKADCGQGDKADEKDGKKKHASSTSDSHILDYYENPAIKEEISTLVGDVLSSCKDETGQSLREETEPQVQKFRVTCNRAGEKHCFTSNEAARDFGGAIQEYFKWKADMTNFDVEVLLNIHDNEVIVAIALTEESLHRRNITHFGPTTLRSTLAYGMLRLCEPKPTDVIVDPMCGTGAIPIEGATEWSHCYHIAGDNNPLAVNRAANNISSLLTKSQIKDGKTTWGLPIDAVQWDICNLPLRTASVDIIVTDMPFGKRMGSKKRNWNLYPACLREMSRVCRPGTGRAVLLTQDKKCFTKALSGMGHVWRKVHVVWVNIGGLHAAVYLLKRTAQAFVHPSDQDEGRDPPW----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6A2Z6-1", "uniprot_id": "A0A8I6A2Z6_RAT", "id": "A0A8I6A2Z6-1", "name": "tRNA (guanine(6)-N(2))-methyltransferase THUMP3", "aln": "MTVLTLVRTLKYKKRLHSFSFFFSVLPLETVRPFRNISIMSDTQEATREHLDMNLHENKKPVPLIESGIRSESEHLQVTIGATVPTGFEQTAADEVREKLKSSCRISKDRGKIYFDIAVESLAQVHCLRSVDNLFVVVEEFKDYQFKATKEEVLRDFEELAGKLPWSDPLKVWQINTTFKKKKAKRRKANQSAGREKADCGQGDNAGEKDGKKKLASGAADPHILDYYENPAIKEEISTLIGEVLASGEDENGQSLREEAEPQVQKFRVTCNRAGEKHCFTSNEAARGFGGAVQEYFKWKADMTNFDVEVLLNIHNNEVIVAIALTEESLHRRNITHFGPTTLRSTLAYGMLRLCEPKPTDVIVDPMCGTGAIPIEGATEWSHCYHIAGDNNPLAVNRAANNISSLLTKSQIKDGKTSWGLPIDAVQWDICNLPLRTASVDIIVTDMPFGKRMGSKKRNWNLYPACLREMSRVCRPRTGRAVLLTQDKKCFTKALSGMGHVWRKVHTVWVNIGGLHAAVYLLKRTPQDFVHPSDQDGGKDPPW----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BV44-1", "uniprot_id": "THUM3_HUMAN", "id": "Q9BV44-1", "name": "tRNA (guanine(6)-N(2))-methyltransferase THUMP3", "aln": "---------------------------------------MCDIEEATNQLLDVNLHENQKSVQVTESDLGSESE-LLVTIGATVPTGFEQTAADEVREKLGSSCKISRDRGKIYFVISVESLAQVHCLRSVDNLFVVVQEFQDYQFKQTKEEVLKDFEDLAGKLPWSNPLKVWKINASFKKKKAKRKKINQNSSKEKINNGQEVKIDQRNVKKEFTSHALDSHILDYYENPAIKEDVSTLIGDDLASCKDETDESSKEETEPQVLKFRVTCNRAGEKHCFTSNEAARDFGGAVQDYFKWKADMTNFDVEVLLNIHDNEVIVGIALTEESLHRRNITHFGPTTLRSTLAYGMLRLCDPLPYDIIVDPMCGTGAIPIEGATEWSDCFHIAGDNNPLAVNRAANNIASLLTKSQIKEGKPSWGLPIDAVQWDICNLPLRTGSVDIIVTDLPFGKRMGSKKRNWNLYPACLREMSRVCTPTTGRAVLLTQDTKCFTKALSGMRHVWRKVDTVWVNVGGLRAAVYVLIRTPQAFVHPSEQDGERGTLWQCKE", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* :***.: *.:**. *::.* : **.: **** * ****************.****** *:*:**:******* *:********************:**:***** ******:***:********:*****:**::********:* **.:.:** : ** : .::: **: :* : *.*************::***:*: *:* :**..:* :**:**** **********************.****:*:********************:*****.*********************************:* * *:********************.*:******************:*********:**.:*******************.********:*************************** * **********.********** ******..****:***:****:* **.* *****:** :.. * ", "identical_positions": 390, "similar_positions": 78, "identity": "71.3%" }, { "cls_id": "homologset.agr.MGI:1277977", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8IWV7-1", "uniprot_id": "UBR1_HUMAN", "id": "Q8IWV7-1", "name": "E3 ubiquitin-protein ligase UBR1", "aln": "-MADEEAGGTERMEISAELPQTPQRLASWWDQQVDFYTAFLHHLAQLVPEIYFAEMDPDLEKQ----------------EESVQMSIFTPLEWYLFGEDPDICLEKLK-------HSGAFQLCGRVFKSGETTYSCRDCAIDPTCVLCMDCFQDSVHKNHR--YKMHTSTGGGFCDCGDTEAWKTGPFCVNHEPGRAGTIKENSRCPLNEE-------VIVQARKIFPSVIKYVVEMTIWEEE------KELPPELQIRE----------------------------------------------KNERYYCVLFNDEHHSYDHVIYSLQRALDCELAEAQLHTTAIDKEGRRAVKAG--------------------AYAACQEAKEDIK--------SHSENVSQHPLHVEVLHSE----------IMAHQKFALRLGSWMNKIMSYSSDFR-----------------------------QIFCQACLREEPDSENPCLISRLMLWDAKLYKGARKILHELIFSSFFMEMEYKKLFAMEFVKYYKQLQKEYISDDHDRSIS-ITALSVQMFTVPTLARHLIEEQNVISVITETLLEVLPEYLDRNNKFNFQG--YSQDKLGRVYAVICDLKYILISKPTIWTERLRMQFLEGFRSFLKILTCMQGMEEIRRQVGQHIEVDPDWEAAIAIQMQLKNILLMFQEWCACDEELLLVAYKECHKAVMRCSTSFISSSKTVV-QSCGHSLETKSYRVSEDLVSIHLPLSRTLAGLHVRLSRLGAVSR---LHEFVSFEDFQVEVLVEYPLRCLVLVAQVVAEMWRRNGLSLISQVFYYQD-VKCREEMYDKDIIMLQIGASLMDPNKFLLLVLQRYELAEAFNKTIS-----TKDQDLIKQYNTLIEEMLQVLIYIVGERYVPGVGNVTKE---EVTMREIIHLLCIEPMPHSAIAKNLPENE--NNETGLENVINKVATFKKPG-VSGHGVYELKDESLKDFNMYFYHYSKTQHSKAEHMQKKRRKQENKDEALPPPPPPEFCPAFSKVINLLNCDIMMYILRTVFERAIDTDSNLWTEGMLQMAFHILALGLLEEKQQLQKAPEEEVTFDFYHKASRLGSSAMN---IQMLLEKLKGIPQLEGQKDMITWILQMFDTVKRLREKSCLIVATTSGSE--SIKNDEITHDKEKAERKRKAEAARLHRQKIMAQMSALQKNFIETHKLMYDNTSEMPGKE----------DSIMEEESTPAVSDYSRIALGPKRGPSVTEKEVLTCILCQEEQEVKIENNAMVLSACVQKSTALTQHRGKPIELSGEALDPLFMDPDLAYGTYTGSCGHVMHAVCWQKYFEAVQLSSQQRIHVD---LFDLESGEYLCPLCKS-LCNTVIPIIPLQPQKIN---SEN-ADALAQLLTLARWIQTVLARISGYNIRHAKGENP-IPIFFNQGMGDSTLEFHSILSFGVESSIKYSNSIK-----EMVILFATTIYRIGLKVPPDERDPR-----------------VPMLTWSTCAFTIQAIENLLGDEGKPLFGALQNRQHNGLKALMQFAVAQ-----RITCPQVLIQKHLVRLLSV---------------VLPNIKSEDTPCLLSIDLFHVLVGAVLAFPSLYWDDPVDLQPSSVSSSYNHLYLFHLITMAHMLQILLTVDT----GLPLAQVQEDSEEAHSASSFFAEISQYTSG----------------------------------------SIGCDIPGWYLWVSLKNGITPYLRCAALFFHYLLGVTPPEELHTNS-------AEGEYSALCSYLSLPTNLFLLFQEYWDTVRPLLQRWCADPALLNCLKQ--------KNTVVRYPRKRNSLIELPDDYSCLLNQASHFRCPRSADDERKHPVLCLFCGAILCSQNICCQEIVNGEEVGACIFHAL-HCGAGVCIFLKIRECRVVLVEGKARGCAYPAPYLDEYGETDPGLKRGNPLHLSRERYRKLHLVWQQHCIIEEIARSQETNQMLFGFNWQLL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O70481-1", "uniprot_id": "UBR1_MOUSE", "id": "O70481-1", "name": "E3 ubiquitin-protein ligase UBR1", "aln": "-MADEEMDGAERMDVSPEPPLAPQRPASWWDQQVDFYTAFLHHLAQLVPEIYFAEMDPDLEKQ----------------EESVQMSILTPLEWYLFGEDPDICLEKLK-------HSGAFQLCGKVFKSGETTYSCRDCAIDPTCVLCMDCFQSSVHKNHR--YKMHTSTGGGFCDCGDTEAWKTGPFCVDHEPGRAGTTKESLHCPLNEE-------VIAQARRIFPSVIKYIVEMTIWEEE------KELPPELQIRE----------------------------------------------KNERYYCVLFNDEHHSYDHVIYSLQRALDCELAEAQLHTTAIDKEGRRAVKAG--------------------VYATCQEAKEDIK--------SHSENVSQHPLHVEVLHSV----------VMAHQKFALRLGSWMNKIMSYSSDFR-----------------------------QIFCQACLVEEPGSENPCLISRLMLWDAKLYKGARKILHELIFSSFFMEMEYKKLFAMEFVKYYKQLQKEYISDDHERSIS-ITALSVQMLTVPTLARHLIEEQNVISVITETLLEVLPEYLDRNNKFNFQG--YSQDKLGRVYAVICDLKYILISKPVIWTERLRAQFLEGFRSFLKILTCMQGMEEIRRQVGQHIEVDPDWEAAIAIQMQLKNILLMFQEWCACDEDLLLVAYKECHKAVMRCSTNFMSSTKTVV-QLCGHSLETKSYKVSEDLVSIHLPLSRTLAGLHVRLSRLGAISR---LHEFVPFDGFQVEVLVEYPLRCLVLVAQVVAEMWRRNGLSLISQVFYYQD-VKCREEMYDKDIIMLQIGASIMDPNKFLLLVLQRYELTDAFNKTIS-----TKDQDLIKQYNTLIEEMLQVLIYIVGERYVPGVGNVTRE---EVIMREITHLLCIEPMPHSAIARNLPENE--NNETGLENVINKVATFKKPG-VSGHGVYELKDESLKDFNMYFYHYSKTQHSKAEHMQKKRRKQENKDEALPPPPPPEFCPAFSKVVNLLSCDVMMYILRTIFERAVDMESNLWTEGMLQMAFHILALGLLEEKQQLQKAPEEEVAFDFYHKASRLGSSAMNAQNIQMLLEKLKGIPQLESQKDMITWILQMFDTVKRLREKSCLVVATTSGLE--CVKSEEITHDKEKAERKRKAEAARLHRQKIMAQMSALQKNFIETHKLMYDNTSEVTGKE----------DSIMEEESTSAVSEASRIALGPKRGPAVTEKEVLTCILCQEEQEVKLENNAMVLSACVQKSTALTQHRGKPVDHLGETLDPLFMDPDLAHGTYTGSCGHVMHAVCWQKYFEAVQLSSQQRIHVD---LFDLESGEYLCPLCKS-LCNTVIPIIPLQPQKIN---SEN-AEALAQLLTLARWIQTVLARISGYNIKHAKGEAPAVPVLFNQGMGDSTFEFHSILSFGVQSSVKYSNSIK-----EMVILFATTIYRIGLKVPPDELDPR-----------------VPMMTWSTCAFTIQAIENLLGDEGKPLFGALQNRQHNGLKALMQFAVAQ-----RTTCPQVLIHKHLARLLSV---------------ILPNLQSENTPGLLSVDLFHVLVGAVLAFPSLYWDDTVDLQPSPLSSSYNHLYLFHLITMAHMLQILLTTDTDLSSGPPLAEGEEDSEEARCASAFFVEVSQHTDG----------------------------------------LAGCGAPGWYLWLSLRNGITPYLRCAALLFHYLLGVAPPEELFANS-------AEGEFSALCSYLSLPTNLFLLFQEYWDTIRPLLQRWCGDPALLKSLKQ--------KSAVVRYPRKRNSLIELPEDYSCLLNQASHFRCPRSADDERKHPVLCLFCGAILCSQNICCQEIVNGEEVGACVFHAL-HCGAGVCIFLKIRECRVVLVEGKARGCAYPAPYLDEYGETDPGLKRGNPLHLSRERYRKLHLVWQQHCIIEEIARSQETNQMLFGFNWQLL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M9P0T8-1", "uniprot_id": "A0A8M9P0T8_DANRE", "id": "A0A8M9P0T8-1", "name": "E3 ubiquitin-protein ligase", "aln": "------------MAES----LSAAQLSTKWQEASNRGSAILRYLGEQVPLIYCLEVELQHAEE----------------ELKVEQRLLYPLEYFLFGEEPCVGLEKLQRY----NSSSSAQQCGRVFKEGETVYSCRDCAIDPTCVLCIECFQKSVHKSHR--YKMHASSGGGFCDCGDVEAWKTGPCCSQHDPG-TEATMETDECVMDPG-------LQERAQMLFHLLLQYTTDMLIWEEN------NDLSEELKPKV----------------------------------------------KEDSYFCILYNDEHHSYDHVIYTLQRAIACDQNQAQVYTALIDKEGRRAVKRG--------------------TLRTCQQAKDNIR--------RNSEHIIQKPLRVEVLHTA----------VMAHQTFALRLGAWFQKIIGYSVGFR-----------------------------DVFCQMALEPASDNDKLSLISRLMLHDAKLYKGARKVVHELIFCSLLMDTEYKRQFAMKFTEHYKQLQEDFISDDHQRNIS-ITALSVQIFTVPTLARQLIEEGTVIKVIIDTVMDMMREHLDNNHRFHFQG--HNPDKFFRVQVIFHDLRYILISKPSIWTEALRVKFLEGFRVFLHFLGCMQGMEEVKRQFGQHVEVEPEWEAGFTLQMQLRHILAMFQDWCSSDERVLLLAFQECHRALMSCTNQPFRSEPKDS-YMCKQILHARPYKVSQEPVSIHLPISRLLAGLYVLLCQTGAIQY---LPDFVDPAQLNFTELAEQPLRCIVLAAQVCADMWRRNGLSLVSQVYYYQD-VKCRDEMFDKDVIMLQIAASKMDPNHFLMLVLLRFELFDIFNGNCS-----SKDQEVLKQWNRLTEEMLYLLIIIVGERYVPGISNVTKE---DVIMREVIHLLCIEPMAHSTLIKSLPENE--NHETGLETVIAKVANFKKPG-VSGHGLYNVKKECLKEFNPFFYHYSRPQHSKAEEAQKERRSQESSEKALRPPVPPPFRPAFSSIVNLLCCDIFIHVLRRILQKAVEDRSNQWTEPMIQRALHLVGQALLEETTQLENSSAEEVTFDFSLKAKKTGSEQGKS--LLHFLTKMKSLPSLKVLKDMIAWNLQMFEVVKCLREKSS--PAASFAMD--HSKAEESVQDKE---QKRKAEAAKAHRRKIMAQMSAMQKNFIESNKILYENMPESSSQS----------DTAASLDSFVMDVDKNRVAVGPQQGVWSLDWETLTCILCQEEQEVQAQAPAMVLTACVQRSTVLTQSRGKTLSPK-VDYYPLFMPPDLAVGTHTGSCGHFMHATCWQKYFEAVQSTTRNRLHAEL--IIDLENGEYMCPLCKS-LCNTVIPLIPVEPSSLN---YES-AQLVGQHLTLMRWIQIMSSRIRGLKAMWTADGSD-AAEKAAAPFDEGQTEFRSILSFGVQEPPKFSRSIT-----EMLVVCATTVHRVGLQTPPNDLCPF-----------------VPAMSWNTCAYTIQAVENMLQDEGKALFGSLKNRQLSGLKALVQFSAAQ-----RMKCNQVVIQKHFADMLAV---------------LVPVPHVENTPSILEVDFFHLLVGLVLSIPSLYQEEAVDLQPSAVSTAYNHLYLLQLITVGHMLQVLLAAHD-----CAVMAVAEEGDEAQAAAEFFSTVSQHTDR----------------------------------------MKSGVLS--FSVEGVKRGVLPFLRCAALFFNCLTGVPPPDELSVSAEL-----PESQLPLLCSYLSLPSNLFQLFQDHRDVMTTLINRWCGNTAISKALKG--------EMHMIRYPRKRNRLIDLPEDYSVLLNQASHFKCPNSSDDERKHPTLCLLCGVMLCAQSSCCHEQLNGEEVGACTGHAA-ICGAGVGLFLRVRECEIVLMASKTRGSPYPAPYLDDYGETDPQLGRGNPLHLCPERYRKLLHLWQQHCVLEEIARSLELLNVMFPFEWQML", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VX91-1", "uniprot_id": "UBR1_DROME", "id": "Q9VX91-1", "name": "E3 ubiquitin-protein ligase UBR1", "aln": "--MDRYDMEDVVVAPPAECSSPLKEWRLKRQAGTLDRSDIIEFLKRESPKYFDYQTSATVKDTNVIT------LKCMFKESLAKEEIIDVVVEFMLGDNPSSALEKLR------LEGNTATVCGKVFKNGEPTYSCRECGVDPTCVLCVNCFKRSAHRFHK--YKMSTSGGGGCCDCGDDEAWKKDQYCELHLANRKNPLESK---ILTDA-------VLERVEICFGAILAFCVSYLEIEPN------ASLQCLDGNVEG------------------------------------------GQVDGAQYCTVLYNDESHTFDQVIQTLTKIAKCRAKDAMEIVAAIDREGRAVVKCD--------------------TFEECNKLKVSIENQMILPTSLVSTARNNQSLRTSVLHIG----------AVACQQFALQLLGWFQEFLVRHYLFR-----------------------------KTFSELVQRK----QETFCIRHILEYDVKLWKTARTCWHRLLISGMLMEYDNKMILAQEFSRRYATIVEDFISDDHDHAFS-IVSLSVQLFTVPSIAHHLIAHEGIFDKLLHTFYHVAIEKFIRNKTLHFSKNIASLTFFKRANYILYDLRYLLSLKPDVLSNDLRNGFLEGCRALMRVLNVMQGMESMTRQTGQHMDYEPEWECAFNLHIKLATTISQVIDWASGDVKLLRKLYKMTMRALVSNSFIVGGEKVMQPKKVADHVANCLVYDISVQPVSIHLPLSRFFAGIYLHLGAHDLTYDGLQTETEALSIKLTPREIIEPVLCTQAMIAQVGAGLWRRNGYTLLHQLYFYRN-VRCRVEMLDRDIACLQIGASLMESNEFLIHVLNRFNTIPWLQENYWSLLSGNEMNDDIIREASIFDEFLELLIVIIGERWMPGVSMVTEE---DRLRKEIIQLLCIKPYSHSELSRALPDGNSGNSDNVFEEVINTVAVFKKPVGADSKGVYELKEHLLKEFNMYFYHYTKEDKSKAEELQRERRKAKKQLVCCPPPMLPKLTPAFTPMANILQCPVFLNICSLIMERALNAYSRSFTESHLQKVLHLLGYAIQEELS------EHYPFLSFYERSQEYG--------ILEKLEELARCPRLEAHYDFVLWTIERFKQLQAKQAPSDGRAGPSCSQQGTGGKLSLSAEEQAREERENRARLAAERRAHIMAQMQKAQKSFISSNAEMFADTENETRKESASTGPMDWEDIPPEEEQGAVALESKVACLGPDRKFYHGTDDTFKCILCFENCAISRGGRQLVSSAFVQTSRVIFTTPN---------------LRNSQSALHISCCGHVMHYSCWLEYFTNEEFKELRRPHRNRAALAQAANVEFQCPYCRT-LSNAIIPVTETLPAFSA---PPSPNESYLPLDSFVEIMSTLAIELGNVKDHELTTLPSVSNILRLSGVVGGLAQFERSVQLIKNPPRLHADYIEGIEFLKKALLNTMKIQQSHLKDHPAIESIE-----------------MVPILWDSCSYTLQALEIYLYAVEKPLKAELSMRHQSCARNLVRACSRSSALEWETDLPLLPPMRSQAEFSSR---------------LLDTIFNQNDTSVLEWDCFRVLVPFQFGVLNLMVPE-KGYKTIIPSGSMFDFYIMQTMFLAQLTKAVLCFDVE---KEKAKRAEKAPNSELTQLDYIEQLPSRIRDNMIDFYRRYNIPARVLQKTKQKQLVEEESEENQGHGQTVVIPCESHHLALLLEYVQRQMSSFLRCSCLFYRFLTDVDFPDTFPTDQ--------PDRFDLMCQYLGLDP-MLGVYFDMETVYATMMHSFASHPHIDREVEQRCQPDARRSLQVEPCLRPLPRLKVLCDDFSDLINSVSDIFCPNNEREEMKTPTMCLICGLILCGQSYCCQPELGKVSVGACTHHAH-ACGAEVGIFLRIRDCQVVYLG-RGKGCFVPPPYLDEYGETDMGLRRGNPLRLSQAAYRKIYLQWLGHGLHGEIARLNDNANVAAAAQWHHM", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P19812-1", "uniprot_id": "UBR1_YEAST", "id": "P19812-1", "name": "E3 ubiquitin-protein ligase UBR1", "aln": "MSVADDDLGSLQGHIRRTLRSIHNLPYFRYTRGPTERADMSRALKEFIYRYLYFVISNSGENLPTLFNAHPKQKLSNPELTVFPDSLEDAVDIDKITSQQTIPFYKIDESRIGDVHKHTGRNCGRKFKIGEPLYRCHECGCDDTCVLCIHCFNPKDHVNHHVCTDICTEFTSGICDCGDEEAWNSPLHCKAEEQENDISEDPATNADIKEEDVWNDSVNIALVELVLAEVFDYFIDVFNQNIEPLPTIQKDITIKLREMTQQGKMYERAQFLNDLKYENDYMFDGTTTAKTSPSNSPEASPSLAKIDPENYTVIIYNDEYHNYSQATTALRQGVPDN-VHIDLLTSRIDGEGRAMLKCSQDLSSVLGGFFAVQTNGLSATLTSWSEYLHQETCKYIILWITHCLNIPNSSFQTTFRNMMGKTLCSEYLNATECRDMTPVVEKYFSNKFDKNDPYRYIDLSILADGNQIPLGHHKILPESSTHSLSPLINDVETPTSRTYSNTRLQHILYFDNRYWKRLRKDIQNVIIPTLASSNLYKPIFCQQVVEIFNHITRSVAYMDREPQLTAIRECVVQLFTCPTNAKNIFENQSFLDIVWS-IIDIFKEFCKVEGGVLIWQRVQKSNLTKSYSISFKQGLYTVETLLSKVHDPNIPLRPKEIISLLTLCKLFNGAWKIKRKEGEHVLHE---DQNFISYLEYTTSIYSIIQTAEKVSEKSKDSIDSKLFLNAIRIISSFLGNRSLTYKLIYDSHEVIKFSVSHERVAFMNPLQTMLSFLIEKVSLKDAYEA--------LEDCSDFLKISDFSLRSVVLCSQIDVGFWVRNGMSVLHQASYYKNNPELGSYSRDIHLNQLAILWERDDIPRIIYNILDRWELLDWFTGEVD-----YQHTVYEDKISFIIQQFIAFIYQILTERQYFKTFSSLKDRRMDQIKNSIIYNLYMKPLSYSKLLRSVPDYLT-EDTTEFDEALEEVSVFVEPKGLADNGVFKLKASLYAKVDPLKLLNLENEFESSATIIKSHLAKDKDEIAKVVLIPQVSIKQLDKDALNLGAFTRNTVFAKVVYKLLQVCLDMEDSTFLNELLHLVHGIFRDDELINGKDSIPEAYLSKPICNLLLSIANAKS---DVFSESIVRKADYLLEKMIMKKPNELFESLIASFGNQYVNDYKDKKLR--------QGVNLQETEKERKRRLAKKHQARLLAKFNNQQTKFMKEHESEFDEQDNDVDMVG---------EKVYESEDFTCALCQD-----------SSSTDFFVIPAYHDHSPIFRPGNIFNPNEFMPMWDGFYNDDEKQAYIDDDVLEALKENGSCGSRKVFVSCNHHIHHNCFKRYVQKKRFSSNAFICPLCQTFSNCTLPLCQTSKANTGLSLDMFLESELSLDTLSRLFKPFTEENYRTINSIFSLMISQCQGFDKAVRKRANFSHKDVSLILSVHWANTISMLEIASRLEKPYSISFFRSREQKYKTLKNILVCIMLFTFVIGKPSMEFEPYPQQPDTVWNQNQLFQYIVRSALFSPVSLRQTVTEALTTFSRQFLRDFLQGLSDAEQVTKLYAKASKIGDVLKVSEQMLFALRTISDVRMEGLDSESIIYDLAYTFLLKSLLPTIRRCLVFIKVLHELVKDSENETLVINGHEVEEELEFEDTAEFVNKALKMITEKESLVDLLTTQESIVSHPYLENIPYEYCGIIKLIDLSKYLNTYVTQS------------------------------------KEIKLREERSQHMKNADNRLDFKICLTCGVKVHLRADRHEMTKHLNKNCFKPFGAFLMPNSSEVCLHLTQPPSNIFISAPYLNSHGEVGRNAMRRGDLTTLNLKR---YEHLNRLWINNEIPGYISRVMGDEFRVTILSNGFLFAFNREPRPRRIPPTDEDDEDMEEGEDGFFTEGNDEMDVDDETGQAANLFGVGAEGIAGGGVRDFFQFFENFRNTLQPQ----GNGDDDAPQNPPPILQFLGPQFDGATIIRNTNPRNLDEDDSDDNDDSDEREIW---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . * . . . : : : .: : *: : **: ** **. * *::*. * *****:.**: . * *: .: :. .* ***** ***:. * . . : .. : :: : . : : .: . * :::*** *.:.:. :* : . .: ** *** :* . . .: . . : .::. . : : :: : ::.: : :* . : : . : ::: * : :* *. :.::: : . * :. :. . : : .. *:: :: * **::* *: *:::: . .:. : . .: * : . : . : : * : : : :: . ::* .: *: *:*: : : : :: : . : . . . . : :* : *:: *:. :: : : . : : * .: :*: . :* *** ::: * :*:: . * .: * * . : .:: :* *:: : : : : :::: .: *: ** .: : ..: * ::* .:* : : :*: : . :: .: *: * :* .:*::::* ..: . : ..: :.: ... . : * . : :. : :: . :: :*:: : :: :. . .: . :: : *. : . : ::.: . * :: :::*::. *..*:. : : : : : . :. . : : :. : : . : : . .*.* :* *: .*. . . : : . ..: *. :: : :: : : :. : . . :: : : . : :.. : . * : * *. : . . : : . :: :: . :: ** : . : . : :: : . :* . : : . * *. .. .. : . . :* :* . : : : . : . : ::: : . . : . . : * : .:. . .*. :* *. . : .. . . :. * *: * *:: : : : : : * ", "identical_positions": 121, "similar_positions": 437, "identity": "5.91%" }, { "cls_id": "homologset.agr.MGI:1277978", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O00422-1", "uniprot_id": "SAP18_HUMAN", "id": "O00422-1", "name": "Histone deacetylase complex subunit SAP18", "aln": "MA-VESRVTQEEIKKEPEKPIDREKTCPLLLRVFTTNNGRHHRMDEFSRGNVPSSELQIYTWMDATLKELTSLVKEVYPEARKKGTHFNFAIVFTDVKRPGYRVKEIGSTMSGRKGTDDSMTLQSQKFQIGDYLDIAITPPNRAPPPSGRMRPY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O55128-1", "uniprot_id": "SAP18_MOUSE", "id": "O55128-1", "name": "Histone deacetylase complex subunit SAP18", "aln": "MA-VESRVTQEEIKKEPEKPIDREKTCPLLLRVFTTNNGRHHRMDEFSRGNVPSSELQIYTWMDATLKELTSLVKEVYPEARKKGTHFNFAIVFMDLKRPGYRVKEIGSTMSGRKGTDDSMTLQSQKFQIGDYLDIAITPPNRAPPSSGRMRPY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9VEX9-1", "uniprot_id": "SAP18_DROME", "id": "Q9VEX9-1", "name": "Histone deacetylase complex subunit SAP18", "aln": "MANVESMIVEEKTQ---VKQIDREKTCPMLLRVFCS-TGRHHSVSEYMFGNVPTNELQIYTWQDATLHELTSLVRDVNPDTRKKGTYFDFAVVYPNFRSNHFQMREIGVTCTGQKGIDDNKTLAQAKFSIGDFLDISITPPNRLPPTARRQRPY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** *** :.:*: : * ********:***** : .**** :.*: ****:.******* ****:******::* *::*****:*:**:*: :.: ::::*** * :*:** **. ** . **.***:***:****** **.: * ***", "identical_positions": 88, "similar_positions": 38, "identity": "57.14%" }, { "cls_id": "homologset.agr.MGI:1277979", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P05107-1", "uniprot_id": "ITB2_HUMAN", "id": "P05107-1", "name": "Integrin beta-2", "aln": "-----------MLGLRPPLLALVGLLSLGCVLSQECTKFKVS--SCRECIESGPGCTWCQKLNFTGP-----------------------------------------GDPDSIRCDTRPQLLMRGCAADDIMDPTSLAET-----QEDHNGGQKQLSPQKVTLYLRPGQAAAFNVTFRRAKGYPIDLYYLMDLSYSMLDDLRNVKKLGGDLLRALNEITESGRIGFGSFVDKTVLPFVNTHPDKLRNPCPNKEKECQPPFAFRHVLKLTNNSNQFQTEVGKQLISGNLDAPEGGLDAMMQVAACPEEIGWRNVTR-LLVFATDDGFHFAGDGKLGAILTPNDGRCHLEDN-LYKRSNEFDYPSVGQLAHKLAENNIQPIFAVTSRMVKTYEKLTEIIPKSAVGELSEDSSNVVHLIKNAYNKLSSRVFLDHNALPDTLKVTYDSFCSNGVTHRNQPRGDCDGVQINVPITFQVKVTATECIQE-----QSFVIRALGFTDIVTVQVLPQCECRCRDQS-----RDRSLCHGKGFLECGICRCDTGYIGKNCECQTQGRSSQELEG-SCRKD-NNSIICSGLGDCVCGQCLCHTSDVPGKLIYGQYCECDTINCERYNGQVCGGPGRGLCFCGKCRCHPGFEGSACQCERTTEGCLNPRR-VECSGRGRCRCNVCECHSG----YQLPLCQECPGCPSPCGKYISCAECLKFEKGPFGKNCSAACPGLQLSNNPVKGRTCK-ERDSEGCWVAYT-----LEQQDGMDRYLIYVDESRECVAGPNIAAIVGGTVAGIVLIGILLLVIWKALIHLSDLREYRRFEKEKLKSQWNN-DNPLFKS--ATTTVMNPKFAES-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3UV74-1", "uniprot_id": "ITB2L_MOUSE", "id": "Q3UV74-1", "name": "Integrin beta-2-like protein", "aln": "-----------MLGQCTLLPVLAGLLSLESALSQLCTKDNVS--TCQDCIRSGPSCAWCQKLNFTGR-----------------------------------------GEPDSVRCDTPEQLLLKGCTSEYLVDPKSLAES-----QEDKERDQRQLSPRNVTVFLRPGQAATFKVDFQRTQDNSVDLYFLMGLSGSAQGHLSNVQTLGSDLLKALNEISRSGRIGFGSIVN----------------------------MTFQHILKLTADSSQFQRELRKQLVSGKLATPKGQLDAVVQVAICLGEIGWRNGTR-FLVLVTDNDFHLAKDKTLGTRQNTSDGRCHLDDG-MYRSRGEPDYQSVVQLASKLAENNIQPIFVVPSRMVKTYEKLTTFIPKLTIGELSDDSSNVAQLIRNAYSKLSSIVVLNHSTIPSILKVTYDSYCSNGTSNPGKPSGDCSGVQINDQVTFQVNITASECFRE-----QFFFIQALGFMDSVTVRVLPLCECQCQEQS-----QHHSLCGGKGAMECGICRCNSGYAGKNCECQTQGPSSQDLEG-SCRKD-NSSIMCSGLGDCICGQCECHTSDIPNKEIYGQYCECNNVNCERYDGQVCGGPERGHCSCGRCFCRYGFVGSACQCRMSTSGCLNNRM-VECSGHGRCYCNRCLCDPG----YQPPLCEKRPGYFHRCSEYYSCARCLKDNSAIKCR----ECWNLLFSNTPFSNKTCMTERDSEGCWTTYT-----LYQPDQSDINSIYIKESLVCAEISNTTILLG-VIVGVLLAVIFLLVY--CMVYLKGTQKAAKLPRKGGAQSTLA-QQPHFQEPHHVEPVWNQERQGTQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P11584-1", "uniprot_id": "ITBX_DROME", "id": "P11584-1", "name": "Integrin beta-PS", "aln": "MILERNRRCQLALLMIAILAAIAGQTDAQKAAKLTAVSTCASKEKCHTCIQT-EGCAWCMQPDFKGQSRCYQNTSSLCPEEFAYSPITVEQILVNNKLTNQYKAELAAGGGGSAMSGSSSSSYSSSSSSSSFYSQSSSGSSSASGYEEYSAGEIVQIQPQSMRLALRVNEKHNIKISYSQAEGYPVDLYYLMDLSKSMEDDKAKLSTLGDKLSETMKRITNNFHLGFGSFVDKVLMPYVSTIPKKLEHPCEN----CKAPYGYQNHMPLNNNTESFSNEVKNATVSGNLDAPEGGFDAIMQAIACRSQIGWREQARRLLVFSTDAGFHYAGDGKLGGVIAPNDGECHLSPKGEYTHSTLQDYPSISQINQKVKDNAINIIFAVTASQLSVYEKLVEHIQGSSAAKLDNDSSNVVELVKEEYRKISSSVEMKDNATGDVKITYFSSCLSNGPE---VQTSKCDNLKEGQQVSFTAQIQLLKCPEDPRDWTQTIHISPVGINEVMQIQLTMLCSCPCENPGSIGYQVQANSCSGHGTSMCGICNCDDSYFGNKCECSATDLTSKFANDTSCRADSTSTTDCSGRGHCVCGACECHKRPNPIEIISGKHCECDNFSCERNRNQLCSGPDHGTCECGRCKCKPGWTGSNCGCQESNDTCMPPGGGEICSGHGTCECGVCKCTVNDQGRFSGRHCEKCPTCSGRCQELKDCVQCQMYKTGELKNGDDCARNCTQFVPVGVEKVEIDETKDEQMCKFFDEDDCKFMFKYSEQGELHVYAQENKECPAKVFMLGIVMGVIAAIVLVGLAILLLWKLLTTIHDRREFARFEKERMNAKWDTGENPIYKQ--ATSTFKNPMYAGK-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . * .:.* . . . ... .* .*: **.: .*:** : :*.* * .* ..: . ..::. : . .* ..: :* *:.*:.: : ** .: ::: : :::. .:***:**.** * .. ::..**..* .:::.*:.. ::****:*: ::: : *. ::..*. *: : :**:* :*:* :**::*. * :****: :* :**: ** .** * * .** ..**.***. * ** *: *: *: :* *: **.*.: :..****. * : .:*.:*****..*::: * *:** * :...: . . :.* *** ..*..:: . ::* .:: :* .: * : * .:*: : : ::: *.* *.: . . . * *:* ****.*: .* *::***.: . :*: :. *** * ..: *** *.*:** * **. * : * *::***:...*** .*:*.** :* * **:* *: *: ** * *. :.. *: ***:* * *. * * . :. *:: * * : .*..* :.. . : .. :*.: * : : . . :* .*. * :: .:..::* : :*: : : . :: :: :: . ::* ::. . .. * . ", "identical_positions": 185, "similar_positions": 266, "identity": "21.59%" }, { "cls_id": "homologset.agr.MGI:1277980", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O89101-1", "uniprot_id": "FGF18_MOUSE", "id": "O89101-1", "name": "Fibroblast growth factor 18", "aln": "MYSAPSACTCLCLHFLLLCFQVQVLAAEENVDFRIHVENQTRARDDVSRKQLRLYQLYSRTSGKHIQVLGRRISARGEDGDKYAQLLVETDTFGSQVRIKGKETEFYLCMNRKGKLVGKPDGTSKECVFIEKVLENNYTALMSAKYSGWYVGFTKKGRPRKGPKTRENQQDVHFMKRYPKGQAELQKPFKYTTVTKRSRRIRPTHPG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O88182-1", "uniprot_id": "FGF18_RAT", "id": "O88182-1", "name": "Fibroblast growth factor 18", "aln": "MYSAPSACTCLCLHFLLLCFQVQVLAAEENVDFRIHVENQTRARDDVSRKQLRLYQLYSRTSGKHIQVLGRRISARGEDGDKYAQLLVETDTFGSQVRIKGKETEFYLCMNRKGKLVGKPDGTSKECVFIEKVLENNYTALMSAKYSGWYVGFTKKGRPRKGPKTRENQQDVHFMKRYPKGQTELQKPFKYTTVTKRSRRIRPTHPG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O76093-1", "uniprot_id": "FGF18_HUMAN", "id": "O76093-1", "name": "Fibroblast growth factor 18", "aln": "MYSAPSACTCLCLHFLLLCFQVQVLVAEENVDFRIHVENQTRARDDVSRKQLRLYQLYSRTSGKHIQVLGRRISARGEDGDKYAQLLVETDTFGSQVRIKGKETEFYLCMNRKGKLVGKPDGTSKECVFIEKVLENNYTALMSAKYSGWYVGFTKKGRPRKGPKTRENQQDVHFMKRYPKGQPELQKPFKYTTVTKRSRRIRPTHPA", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*************************.************************************************************************************************************************************************************.***********************.", "identical_positions": 204, "similar_positions": 3, "identity": "98.55%" }, { "cls_id": "homologset.agr.MGI:1277988", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WTZ0-1", "uniprot_id": "UXT_MOUSE", "id": "Q9WTZ0-1", "name": "Protein UXT", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MATPPKR-------RALDTVGEKVLRYETFISDVLQRD--------------------------------LQKVLDHRDKVYEQLSVYLQLRNVIERLQETNHSELYMQVDLGCNFFVDTVVPDTSRIYVALGYGFFLELTLAEALKFIDRKSSLLTELSDSLTKDSMNIKAHIHMMLEGLREL-----------------------------------------------QGLQNFPEPSPH------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63ZY7-1", "uniprot_id": "UXT_RAT", "id": "Q63ZY7-1", "name": "Protein UXT", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MATPPKR-------RALDTVGEKVLRYEAFISDVLQRD--------------------------------LQKVLDHRDKVYEQLSVYLQLRNVIERLQETNHSELYMQVDLGCNFFVDTMVPDTSRIYVALGYGFFLELTLAEALKFIDRKSSLLTELSDSLTKDSMNIKANIHMMLEGLREL-----------------------------------------------QGLQNFPEPSPH------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UBK9-1", "uniprot_id": "UXT_HUMAN", "id": "Q9UBK9-1", "name": "Protein UXT", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MATPPKR-------RAVEATGEKVLRYETFISDVLQRD--------------------------------LRKVLDHRDKVYEQLAKYLQLRNVIERLQEAKHSELYMQVDLGCNFFVDTVVPDTSRIYVALGYGFFLELTLAEALKFIDRKSSLLTELSNSLTKDSMNIKAHIHMLLEGLREL-----------------------------------------------QGLQNFPEKPHH------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VJP9-1", "uniprot_id": "Q9VJP9_DROME", "id": "Q9VJP9-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQVNPKHNTEAHRQAEQDANKARITQIEEFINEVLKED--------------------------------LRELEKCIGQYNEEIMEYVQLKNTLQTFDTHLPDGYKTQVNIGSNVFMQARVRKMDSILVDVGKNVFLDMSIPDAERFCDTRVKILTKQSDVLRDESVKKRAQIKMALIAISER-----------------------------------------------TKLIQQDESK--------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P43573-1", "uniprot_id": "BUD27_YEAST", "id": "P43573-1", "name": "Bud site selection protein 27", "aln": "MDLLAASVESTLKNLQDKRNFLSEQREHYIDIRSRLVRFINDNDDGEEEGEGQGMVFGDIIISTSKIYLSLGYEYYVEKTKEEAITFVDDKLKLMEDAIEQFNLKIEEAKKTLDNLNHMEDGNGIEEDEANNDEDFLPSMEIREELDDEGNVISSSVTPTTKQPSQSNSKKEQTPAVGPKEKGLAKEKKSKSFEENLKGKLLKRNDEVKKKVQPSKVDTENVYTFADLVQQMDQQDELEDGYIETDEINYDYDAFENSNFKVNDNYEEDDEDEDEEEYLNHSIIPGFEAQSSFLQQIQRLRAQKQSQDHEREEGDVNKSLKPILKKSSFAENSDKKQKKKQVGFASSLEIHEVENLKEENKRQMQSFAVPMYETQESTGIANKMTSDEFDGDLFAKMLGVQEADEVHEKYKEELINQERLEGEASRSNRRTRVSRFRKDRASKKENTLSTFKQETTRSVENEVVEKEPVVGDIIEKEPVVGDVIEKEPVVGDVIEKEPAVTDIVEREPAVNDIVERKPVVGDIIEKEPTINDIVEKEPEINSKSEFETPFKKKKLKSLQKPRSSKSMKKKFDPKILENISDDDYDDDDDGNKKLLSNKSKNNTDEQDKFPSKIQEVSRSMAKTGATVGSEPVRITNVDYHALGGNLDDMVKAYSLGLYDDDLEEDPGTIVEKLEDFKEYNKQVELLRDEIRDFQLENKPVTMEEEENDGNVMNDIIEHEFPESYTNDEDEVALHPGRLQEEVAIEYRRLKEATASKWQSSSPAAHTEGELEPIDKFGNPVKTSRFRSQRLHMDSKP", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. : .: . * .:.::::.: :..: . : : :.: :: . :. . . : .. .: ::: : * . .:*:: *. .:. : ::*: .: : * : * ", "identical_positions": 7, "similar_positions": 58, "identity": "0.88%" }, { "cls_id": "homologset.agr.MGI:1277989", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CZN7-1", "uniprot_id": "GLYM_MOUSE", "id": "Q9CZN7-1", "name": "Serine hydroxymethyltransferase, mitochondrial", "aln": "----------MVSFSLLRTTRPLQR----------CGQLVCMAARAQ------------HSKVAQTQAGEAAGGWTGQESLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGGAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAAYTALLQPHDRIMGLDLPDGGHLTHGYMSDV-KRISATSIFFESMPYKLNPQTGLIDYDQLALTARLFRPRLIIAGTSAYARLIDYARMREVCDEVRAHLLADMAHISGLVAAKVIPSPFKYADVVTTTTHKTLRGARSGLIFYRKGVRTVDPKTGKEIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLRNAQAMADALLKRGYSLVSGGTDTHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKRKT-----AKLQDFKSFLLKDPETSQRLANLRQQVEQFARGFPMPGFDER", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P34897-1", "uniprot_id": "GLYM_HUMAN", "id": "P34897-1", "name": "Serine hydroxymethyltransferase, mitochondrial", "aln": "----------MLYFSLFWAARPLQR----------CGQLVRMAIRAQ------------HSNAAQTQTGEANRGWTGQESLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGGAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLPDGGHLTHGYMSDV-KRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSAYARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGARSGLIFYRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKSKT-----AKLQDFKSFLLKDSETSQRLANLRQRVEQFARAFPMPGFDEH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W457-1", "uniprot_id": "Q9W457_DROME", "id": "Q9W457-1", "name": "Serine hydroxymethyltransferase", "aln": "MQRARSTLTQKLRFCLSRDLNTKVGNPVNFETGKLSGALTRIAAKKQPSPTPFLPAIRRYSDSKQSTLKNMADQKLLQTPLAQGDPELAELIKKEKERQREGLEMIASENFTSVAVLESLSSCLTNKYSEGYPGKRYYGGNEYIDRIELLAQQRGRELFNLDDEKWGVNVQPYSGSPANLAVYTGVCRPHDRIMGLDLPDGGHLTHGFFTPT-KKISATSIFFESMPYKVNPETGIIDYDKLAEAAKNFRPQIIIAGISCYSRLLDYARFRQICDDVGAYLMADMAHVAGIVAAGLIPSPFEWADIVTTTTHKTLRGPRAGVIFFRKGVRSTKAN-GDKVLYDLEERINQAVFPSLQGGPHNNAVAGIATAFKQAKSPEFKAYQTQVLKNAKALCDGLISRGYQVATGGTDVHLVLVDVRKAGLTGAKAEYILEEVGIACNKNTVPGDKSAMNPSGIRLGTPALTTRGLAEQDIEQVVAFIDAALKVGVQAAKLAGS---PKITDYHKTLAENVELKAQVDEIRKNVAQFSRKFPLPGLETL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P37291-1", "uniprot_id": "GLYC_YEAST", "id": "P37291-1", "name": "Serine hydroxymethyltransferase, cytosolic", "aln": "--------------------------------------------MPY-----------TLSDAHHK---------LITSHLVDTDPEVDSIIKDEIERQKHSIDLIASENFTSTSVFDALGTPLSNKYSEGYPGARYYGGNEHIDRMEILCQQRALKAFHVTPDKWGVNVQTLSGSPANLQVYQAIMKPHERLMGLYLPDGGHLSHGYATEN-RKISAVSTYFESFPYRVNPETGIIDYDTLEKNAILYRPKVLVAGTSAYCRLIDYKRMREIADKCGAYLMVDMAHISGLIAAGVIPSPFEYADIVTTTTHKSLRGPRGAMIFFRRGVRSINPKTGKEVLYDLENPINFSVFPGHQGGPHNHTIAALATALKQAATPEFKEYQTQVLKNAKALESEFKNLGYRLVSNGTDSHMVLVSLREKGVDGARVEYICEKINIALNKNSIPGDKSALVPGGVRIGAPAMTTRGMGEEDFHRIVQYINKAVEFAQQVQQSLP----KDACRLKDFKAKVDEGSDVLNTWKKEIYDWAGEYPLAV----", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P37292-1", "uniprot_id": "GLYM_YEAST", "id": "P37292-1", "name": "Serine hydroxymethyltransferase, mitochondrial", "aln": "-------------------------------------MFPRASALAK-----------CMATVHRRGLLTSGAQSLVSKPVSEGDPEMFDILQQERHRQKHSITLIPSENFTSKAVMDLLGSELQNKYSEGYPGERYYGGNEIIDKSESLCQARALELYGLDPAKWGVNVQPLSGAPANLYVYSAIMNVGERLMGLDLPDGGHLSHGYQLKSGTPISFISKYFQSMPYHVDHTTGLIDYDNLQVLAKAFRPKVIVAGTSAYSRLIDYARFKEISQGCGAYLMSDMAHISGLVAANVVPSPFEHSDIVTTTTHKSLRGPRGAMIFFRKGIKSVT-KKGKEIPYELEKKINFSVFPGHQGGPHNHTIGAMAVALKQAMSPEFKEYQQKIVDNSKWFAQELTKMGYKLVSGGTDNHLIVIDLSGTQVDGARVETILSALNIAANKNTIPGDKSALFPSGLRIGTPAMTTRGFGREEFSQVAKYIDSAVKLAENLKTLEPTTKLDARSRLNEFKKLCNESSEVA-ALSGEISKWVGQYPVPGDI--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : : ***: .::: * .** ..: :*.**** * :.:: *.: * ********* ***** * :*. * *.* *. : : : :******. **:**** .* .: . :*:*** *******:**: ** * :*:*:**::: **:***: * * :**::::** *.*.**:** *::::.: *:*: ****::*::** ::****: :*:*******:***.*..:**:*:*::: : * :: * :*. ** :***. ******:::..:*.*:*** :* *: *. ::: *:: : . : . ** :.:.*** *::::.: : **:.* : . :.*: ***: ***:**: *.*:*:*:**:*:* : .::: ::. :*: .::.. : :. * . .: .: :*:. ", "identical_positions": 166, "similar_positions": 162, "identity": "30.63%" }, { "cls_id": "homologset.agr.MGI:1277991", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M0Y6-1", "uniprot_id": "F1M0Y6_RAT", "id": "F1M0Y6-1", "name": "", "aln": "---------------------------------MAVPAALIPPTQLVPPQPPISTSASSSGTTTSTSSATSSPAPSIGPPASSGPTLFRPEPIASSASSSAATTVTSPGGGG--SGGGGGSGGNGGGGGG----SNCNPSLAAGSN---GGGGGVSAGGGGASSTPITASTGSSSSSSSSSSSSSSSSSSSSSSSSSSSCGPLPGKPVYSTPSPVENTPQNNECKMVDLRGAKVASFTVEGCELICLPQAFDLFLKHLVGGLHTVYTKLKRLEITPVVCNVEQVRILRGLGAIQPGVNRCKLISRKDFETLYNDCTNA----------------SSRPGRPPKRTQSVTSPENSHIMPH--------------------------------------------------SVPGLMSPGIIPP--------TGLTAAAAAAA---NAAIAEAMKVKKIKLEAMSNYHASNNQHGADSENGDMNSSVGSSGGSWDKETLHSPPSQGSQAPVAHARIPAAYSLPVSHPLNHLQHSHLPPNGLELPFMMMPHPLIPVSLPPASVTMAMSQMNHLSTIANMAAAAQVQSPPSRVETSVIKERVPDSPSPAPSLEEGRRPGSHPSSHRSSSVSSSPARTESSSDRIPVHQNGLSMNQMLMGLSPN-VLPGPKEGDLAGHDMGHESKRIHIEKDETPLSTPTARDS----------------------MDKLSLAGHGQPLPPGFPSPFLFPDG-----LSSIETLLTNIQGLLKVAIDNARAQEKQVQLEKTELKMDFLRERELRETLEKQLAMEQKNRAIVQKRLKKEKKAKRKLQEALEFET-----------------------------------------------------------------KRREQAEQTLKQAASADSLR----------------------------------------------------------------------------------------------------------------------VLNDSLTPEIEADRSGGRADAERTIQD-----GRLYLKTTVMY----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QYB2-1", "uniprot_id": "DACH1_MOUSE", "id": "Q9QYB2-1", "name": "Dachshund homolog 1", "aln": "---------------------------------MAVPAALIPPTQLVPPQPPISTSASSSGTTTSTSSATSSPAPSIGPPASSGPTLFRPEPIASSASSSAAATVTSPGGGGGGSGGGGGSGGNGGGGG-----SNCNPSLAAGSS---GGG--VSAGGGGASSTPITASTGSSSSSSSSSSSSSSSSSSSSSSSSSSSCGPLPGKPVYSTPSPVENTPQNNECKMVDLRGAKVASFTVEGCELICLPQAFDLFLKHLVGGLHTVYTKLKRLEITPVVCNVEQVRILRGLGAIQPGVNRCKLISRKDFETLYNDCTNA----------------SSRPGRPPKRTQSVTSPENSHIMPH--------------------------------------------------SVPGLMSPGIIPP--------TGLTAAAAAAAAATNAAIAEAMKVKKIKLEAMSNYHASNNQHGADSENGDMNSSVGSSGGSWDKETLHSPPSQGSQAPVAHARMPAAFSLPVSHPLNHLQHSHLPPNGLELPFMMMPHPLIPVSLPPASVTMAMSQMNHLSTIANMAAAAQVQSPPSRVETSVIKERVPDSPSPAPSLEEGRRPGSHPSSHRSSSVSSSPARTESSSDRIPVHQNGLSMNQMLMGLSPN-VLPGPKEGDLAGHDMGHESKRIHIEKDETPLSTPTARDS----------------------IDKLSLTGHGQPLPPGFPSPFLFPDG-----LSSIETLLTNIQGLLKVAIDNARAQEKQVQLEKTELKMDFLRERELRETLEKQLAMEQKNRAIVQKRLKKEKKAKRKLQEALEFET-----------------------------------------------------------------KRREQAEQTLKQAASADSLR----------------------------------------------------------------------------------------------------------------------VLNDSLTPEIEADRSGGRADAERTIQD-----GRLYLKTTVMY----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UI36-1", "uniprot_id": "DACH1_HUMAN", "id": "Q9UI36-1", "name": "Dachshund homolog 1", "aln": "---------------------------------MAVPAALIPPTQLVPPQPPISTSASSSGTTTSTSSATSSPAPSIGPPASSGPTLFRPEPIASAAAAAATVTSTGGGGGGGGSGGGGGSSGNGGGGGGGGGGSNCNPNLAAASNGSGGGGGGISAGGGVASSTPINASTGSSSSSSSSSSSSSSSSSSSSSSS---SCGPLPGKPVYSTPSPVENTPQNNECKMVDLRGAKVASFTVEGCELICLPQAFDLFLKHLVGGLHTVYTKLKRLEITPVVCNVEQVRILRGLGAIQPGVNRCKLISRKDFETLYNDCTNA----------------SSRPGRPPKRTQSVTSPENSHIMPH--------------------------------------------------SVPGLMSPGIIPP--------TGLTAAAAAAAAATNAAIAEAMKVKKIKLEAMSNYHASNNQHGADSENGDMNSSVGSSDGSWDKETLPSSPSQGPQASITHPRMPGARSLPLSHPLNHLQQSHLLPNGLELPFMMMPHPLIPVSLPPASVTMAMSQMNHLSTIANMAAAAQVQSPPSRVETSVIKERVPDSPSPAPSLEEGRRPGSHPSSHRSSSVSSSPARTESSSDRIPVHQNGLSMNQMLMGLSPN-VLPGPKEGDLAGHDMGHESKRMHIEKDETPLSTPTARDS----------------------LDKLSLTGHGQPLPPGFPSPFLFPDG-----LSSIETLLTNIQGLLKVAIDNARAQEKQVQLEKTELKMDFLRERELRETLEKQLAMEQKNRAIVQKRLKKEKKAKRKLQEALEFET-----------------------------------------------------------------KRREQAEQTLKQAASTDSLR----------------------------------------------------------------------------------------------------------------------VLNDSLTPEIEADRSGGRTDAERTIQD-----GRLYLKTTVMY----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NA80-1", "uniprot_id": "A0A8M1NA80_DANRE", "id": "A0A8M1NA80-1", "name": "", "aln": "---------------------------------MATPAALLPATPMAH-APPMSISAVVN----SSTPATLSPSPSVTP---AGPSLFRTELLSS-----------------------------------------ASPGIP---------------------------------------------------------IGSLPHKPVYSTPSPVENTPQNNECKMVEVRGAKLASFTVNGNELICLPQAFDLFLKHLVGGLHTVYTKLKRLEITPVVCNVEQVRILRGLGAIQPGVNRCKLISRKDFEVLYNDCTNA----------------SSRPGRPPKRTQNVTSPDSPHVLPH--------------------------------------------------SVSGLMSSGLMSH--------TGLTAAT----------LAEAMK-KKIKLEVMNSYHGNNN-HSADSENGDITSSMG----------------------------------------------------LELPFMMMPHPLIPVSLPPASVTMAMNQMNHLSTIASMAAAAQVQSVPSRMVTSVIKERVPDSPSPVPSLDDGRRSGSHLSSRQSSSVSSSPAHTESSSDRPHLHQNGLSLGHALLGLSPS-APPGPKEGDLATHDTVHETKRASTEKEENVLCTPTSRDS----------------------YERLSHS--GPTLPPGFPAPLLFPEG-----LSSIETLLTNIQGLLKVAIDNARAQEKQVQLERTELKMELYRERELRETLERQLCVEQKNRALIQKRLKKEKKTKRKLQEALEVES-----------------------------------------------------------------KRRDHAEQTLQRTTSCERSP----------------------------------------------------------------------------------------------------------------------IHNDSQQ-ELETIHNTSKTDTERTIQD-----GRLFLKSTMMY----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IP19-1", "uniprot_id": "Q8IP19_DROME", "id": "Q8IP19-1", "name": "", "aln": "MDSVTSEQSENNNNKAGAINNNINSGIERAAGNMNTTAMLMHHQQQQQAAAAAAAAAAQQQQQQHNGRDGSNSSRGANEDRPNGRSSHTGRGSSCSPASSPSRHPSAVSPVSSLNHSMMQQMQQQQQQQQQQQQQQQHHQLSPPPHG-------MPSGNGLPTGLPPRMPHGLPPHSLGLLNSLQMMHHASPLELMAAAHHHVPPRSYNSPPPISTSDPSANECKLVEYRGQKVAAFIISNETMLCLPQAFELFLKHLVGGLHTVYTKLKRLDIVPLVCNVEQVRILRGLGAIQPGVNRCKLLCCKDFDILYRDCTTARCLSIKPPESNSLQFRSSRPGRPPKRGPVGLSLPPTHLSQHPQLKKHRLDNGDYAYENGHISDMKSPLLANGYNPPPINHMAFMQMNAHHPGAAALMSPGMPPHGLHARPESQMLKAAAQNAGMSAANMDALARSGIWENCRAAYEDIVKHLERLREERTDERQQAMGVGGAVVDRVGNVMVAEHKPRDLSSRNCSPTRQSPVLNLSKSGGNTDHGGSNCDAGSERSDCHSVAGSPARGGSRSLDEGSRSGVGGGVASHVGGGIIGVEDDEEEEENLSDENQSEVDERCLAKDDEDLSDTERDNLSTGSAAAAAAAAAAAAHQLHQHAASHHHQTVGLSHLGVVPPHQRGSPSSAEAAAAALQHQRALNYSQLAAAAAVANGAAVGGGAVANGPTGGGGALTPNEALLAANDAAALAGGLALGPLGIDAHAAVPASSTETLLRNIQSLLKVAADNARQQERQISYEKAELKMDVLREREVKDSLERQLVDERKLRVLYQKRFRRERKIRIRYQQQLGGGSGAVKGSPNANGSGGGGSGSACSESEACGGGGGDAKCNNNNNNNNNNNNSNSSSHGGDVETMKENDAGSEKSDKSLASNSSCDVTAGHSAGSVSGSISAGLNCPDSPTHFKREPSSDHEGSVERQPRSSAASLAAHDEDNTKRCGSRDRDERPPSGSAASVAAEGSLAAAAAAAAAAAAAAASNGKGPWSYPGIDLMATGAFWQNYSESLAQELEMERKSRAANAERDVKSPLSERPTAYYKNSVLFGSAN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * ..* *: .. : :* . . ..: . * : . . :. :. :* :. *.*. . *. ****:*: ** *:*:* :.. ::******:********************:*.*:*************************:. ***: **.***.* ********** * .*: * ....***.*: . *.**: * * . : .. . .: : :....: .::* . *.: . .* :: .. . :. . ... : . . . . :* .* .. . *. . . *: *::.* : ::: :**:. * : :*** . * :.*. : : : : : . *.:.:: . : * : . .*. *:. * :. ** **** ***.***** **** **:*:. *::****:. ****::::**:** *:* *.: ***:::*:* : : *: * : ::::::* :* : .:* *:* :. :::** ::. : *.:::: ", "identical_positions": 177, "similar_positions": 189, "identity": "16.27%" }, { "cls_id": "homologset.agr.MGI:1278313", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0M8U6-1", "uniprot_id": "A0ABK0M8U6_RAT", "id": "A0ABK0M8U6-1", "name": "Cochlin", "aln": "MPSSWSPALCLGAWLLLLLLPRLARAEGAGELVPIPITCFTRGLDIRKEKADVLCPGGCSLEEFSVFGNIVYASVSSICGAAVHRGVIGTSGGPVRVYSLPGRENYSSVAANGIQSQTLSRWSASFAVTKGKSSTQEATGRAVSTANPPSG------KRLKKTPEKKTGNKDCKADIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGVGTEGPHVGLVQASEHPKIEFYLKNFTSAKDVLFAIKEVGFRGGNSNTGKALKHTAQKFFTADTGVRKGIPKVVVVFIDGWPSDDIEEAGIVAREFGVNVFIVSVAKPIPEELGMVQDVAFVDKAVCRNNGFFSYHMPNWFGTTKYVKPLVQKLCTHEQMMCSKTCYNSVNIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFEISDIGAKIAAVQFTYDQRTEFSFTDYNTKENVLAVLANIRYMSGGTATGDAISFTVRNVFGPIRDSPNKNFLVIVTDGQSYDDVRGPAAAAHDAGITIFSVGVAWAPLDDLKDMASKPKESHAFFTREFTGLEPIVSDVIRGICRDFLESQQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q62507-1", "uniprot_id": "COCH_MOUSE", "id": "Q62507-1", "name": "Cochlin", "aln": "MPSSRIPALCLGAWLLLLLLPRFARAEGA---VPIPVTCFTRGLDIRKEKADVLCPGGCSLEEFSVFGNIVYASVSSICGAAVHRGVIGTSGGPVRVYSLPGRENYSSVDANGIQSQMLSRWSASFAVTKGKSSTQEATGRAVSTAHPPSG------KRLKKTPEKKTGNKDCKADIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTEGPHVGLVQASEHPKIEFYLKNFTSAKDVLFAIKEVGFRGGNSNTGKALKHTAQKFFTADTGVRKGIPKVVVVFIDGWPSDDIEEAGIVAREFGVNVFIVSVAKPIPEELGMVQDVAFVDKAVCRNNGFFSYHMPNWFGTTKYVKPLVQKLCTHEQMMCSKTCYNSVNIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFEISDIGAKIAAVQFTYDQRTEFSFTDYNTKENVLAVLANIRYMSGGTATGDAIAFTVRNVFGPIRDSPNKNFLVIVTDGQSYDDVRGPAAAAHDAGITIFSVGVAWAPLDDLRDMASKPKESHAFFTREFTGLEPIVSDVIRGICRDFLESQQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43405-1", "uniprot_id": "COCH_HUMAN", "id": "O43405-1", "name": "Cochlin", "aln": "MSAAWIPALGLGVCLLLLPGP--AGSEGA---APIAITCFTRGLDIRKEKADVLCPGGCPLEEFSVYGNIVYASVSSICGAAVHRGVISNSGGPVRVYSLPGRENYSSVDANGIQSQMLSRWSASFTVTKGKSSTQEATGQAVSTAHPPTG------KRLKKTPEKKTGNKDCKADIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTEGPHVGLVQASEHPKIEFYLKNFTSAKDVLFAIKEVGFRGGNSNTGKALKHTAQKFFTVDAGVRKGIPKVVVVFIDGWPSDDIEEAGIVAREFGVNVFIVSVAKPIPEELGMVQDVTFVDKAVCRNNGFFSYHMPNWFGTTKYVKPLVQKLCTHEQMMCSKTCYNSVNIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFEISDIGAKIAAVQFTYDQRTEFSFTDYSTKENVLAVIRNIRYMSGGTATGDAISFTVRNVFGPIRESPNKNFLVIVTDGQSYDDVQGPAAAAHDAGITIFSVGVAWAPLDDLKDMASKPKESHAFFTREFTGLEPIVSDVIRGICRDFLESQQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8AW56-1", "uniprot_id": "Q8AW56_DANRE", "id": "Q8AW56-1", "name": "Cochlin", "aln": "-MSLWFAVLHVLGILSLSWCT--SGSELN---VATPISCGTRAVDLSDTHLLVLCPANCSLWSLSVFGSGVYASISSICGAAIHRGIIGLSGGPVEVHGLQGRTNYLSSYAHGVQSQSLSQWSASFTVARTISLPLEVSSQTSSSAIVASGAAKKPVKKIVKKPPPATAHKDCPVDMALLLDSSYNIGQRRFNLQKNFVSKLATMLKVGTQGPHVGVVQTSETPRTEFYLTNYTTAKDVTFAIKEIPYIGGNTNTGKAILHTVRNFFSPDFGVRRGYPRVIVVFVDGWPSDNVEEAAILARESGINIFFVSVAKPSPEEASLVSDQDFMRKAVCKDNEFFTFTMPSWFSTNKFVKPLAQKLCSIDQMLCSKTCYNSVDLGFLIDGSSSVGDGNFRLVLDLLVSIARSFDISDIGSRIGAIQFTYDQRMEFNFNDHVLKDNALRALQKIPYMSGGTATGDAINFAVRSLFKP-RSSSNRKFLIIITDGQSYDDVRVPAMAAQREGITVYAVGVAWAPMEDLKAMASEPKESHVFFTREFTGLGQFQQPIVRGICRDFTEFN-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ..* : * * . : :* .. .::* **.:*: . : ****..*.* .:**:*. ****:*******:***:*. *****.*:.* ** ** * *:*:*** **:*****:*:: * . *.:.:: *:* .:* *:: *.* *.:*** .*:*:*:*.*:**************.*:* ** :**:*****:**:** *: ****.*:*:**** *****: : ***:*****: **.::**: * ***:* *:*:***:******::***.*:*** *:*:*:****** *** .:*.* *: ****::* **:: **.**.*.*:****.****: :**:*********::.***********.****:*::: .**::*:*****::*.*:******* **.*.*: *:*.* .: :* ************ *:**.:* * *.*.*::**:*:*********: ** **: ***:::*******::**: ***:*****.********* : . ::******* * : ", "identical_positions": 315, "similar_positions": 150, "identity": "56.15%" }, { "cls_id": "homologset.agr.MGI:1278315", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1MAD0-1", "uniprot_id": "F1MAD0_RAT", "id": "F1MAD0-1", "name": "Low-density lipoprotein receptor-related protein", "aln": "------------------------------METAPTRAPPPPPQPLLLLLALCC--------------SLVPAAASP----------LLLFANRRDVRLVDAG--GVKLESTIVASGLEDAAAVDFQFSKGAVYWTDVSEEAIKQTYLNQTG--------AAAQNIVISGLVSPDGLACDWVGKKLYWTDSETNRIEVANLNGTSRKVLFWQDLDQPRAIALDPAHGYMYWTDWGEAPRIERAGMDGS--TRKIIVDSDIYWPNGLTIDLEEQKLYWADAKLSFIHRANLDGSFRQKVVEGSLTHPFALTLSGDTLYWTDWQTRSIHACNKWTGEKRKEILSALYSPMDIQVLSQERQPHFHTPCEEGNGGCSHLCLLSPREPFYSCACPTGVQLQDNGKTCKAGAEEVLLLARRTDLRRISLDTPDFTDIVLQVGDIRHAIAIDYDPLEGYVYWTDDEVRAIRRAYLDGSGAQTLVNTEINDPDGIAVDWVARNLYWTDTGTDRIEVTRLNGTSRKILVSEDLDEPRAIVLHPVMGLMYWTDWGE-NPKIECANLDGRDRHVLVNTSLGWPNGLALDLQEGKLYWGDAKTDKIEVINIDGTKRQTLLEDKLPHIFGFTLLGDFIYWTDWQRRSIERVHKVKAS-RDVIIDQLPDLMGLKAVNVAKVVGTNPCADGNGGCSHLCFFTPHATKCGCPIGLELLSDMKTCIIPEAFLVFTSRATIHRISLETN---NNDVAIPLTGVKEASALDFDVSNNHIYWTDVSLKTISRAFMNGSSVEHVIEFGLDYPEGMAVDWMGKNLYWADTGTNRIEVARLDGQFRQVLVWRDLDNPRSLALDPTKGYIYWTEWGGKPRIVRAFMDGTNCMTLVDKVGRANDLTIDYADQRLYWTDLDT-NMIESSNMLGQER-MVIADDLPYPFGLTQYSDYIYWTDWNLHSIERADKTSGRNRTLIQGHLDFVMDILVFHSSRQDGLNDCVHSNGQCGQLCLAIPG--GHRCGCASHYTLDPSSRNCSPPSTFLLFSQKFAISRMIPDDQLSPDLILPLHGLRNVKAINYDPLDKFIYWVDGR-QNIKRAKDDGTQPSMLTSPSQSLSPDRQPHDLSIDIYSRTLFWTCEATNTINVHRLDGDAMGVVLRGDRDRPRAIAVNAERGYMYFTNMQDHAAKIERASLDGTEREVLFTTGLIRPVALVVDNALGKLFWVDADLKRIESCDLSGANRLTLEDANIVQPVGLTVLGRHLYWIDRQQQMIERVEKTTGDKRTRVQGRVTHLTGIHAVEEVSLEEFSAHPCARDNGGCSHICIAKGDGTPR----CSCPVHLVLLQNLLTCGEPPTCSPDQFACAT-------GEIDCIPGAWRCDGFPECADQSDEEGCPVCSASQFPCARGQCVDLRLRCDGEADCQDGSDEANCDAVCLPNQFRCAS-GQCVLIKQQCDSFPDCADGSDE---LMCEINKPPSDDVPAHSSAIGPVIGIILSLFVMGGVYFVCQRVMCQRYTGASGPFPHEYVGGTPHVPLNFIAPGGSQHGPFPGIPCSKSMMSSVSLVGGRGS-VPLYDRNHVTGASSSSSSSTKATLYPPILNPPPSPATDPSLYNMDMFYSSNIPSTARPYRPYIIRGMAPPTTPCSTDVCDSDYSTSRWKTSK----------------YYLDLNSDSDPYPPPPTPHSQYLS-----AEDSCPPSPVTERS-YCHLFPPPPSPCTDSS----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91VN0-1", "uniprot_id": "LRP5_MOUSE", "id": "Q91VN0-1", "name": "Low-density lipoprotein receptor-related protein 5", "aln": "------------------------------METAPTRAPPPPP-PPLLLLVLYC--------------SLVPAAASP----------LLLFANRRDVRLVDAG--GVKLESTIVASGLEDAAAVDFQFSKGAVYWTDVSEEAIKQTYLNQTG--------AAAQNIVISGLVSPDGLACDWVGKKLYWTDSETNRIEVANLNGTSRKVLFWQDLDQPRAIALDPAHGYMYWTDWGEAPRIERAGMDGS--TRKIIVDSDIYWPNGLTIDLEEQKLYWADAKLSFIHRANLDGSFRQKVVEGSLTHPFALTLSGDTLYWTDWQTRSIHACNKWTGEQRKEILSALYSPMDIQVLSQERQPPFHTPCEEDNGGCSHLCLLSPREPFYSCACPTGVQLQDNGKTCKTGAEEVLLLARRTDLRRISLDTPDFTDIVLQVGDIRHAIAIDYDPLEGYVYWTDDEVRAIRRAYLDGSGAQTLVNTEINDPDGIAVDWVARNLYWTDTGTDRIEVTRLNGTSRKILVSEDLDEPRAIVLHPVMGLMYWTDWGE-NPKIECANLDGRDRHVLVNTSLGWPNGLALDLQEGKLYWGDAKTDKIEVINIDGTKRKTLLEDKLPHIFGFTLLGDFIYWTDWQRRSIERVHKVKAS-RDVIIDQLPDLMGLKAVNVAKVVGTNPCADGNGGCSHLCFFTPRATKCGCPIGLELLSDMKTCIIPEAFLVFTSRATIHRISLETN---NNDVAIPLTGVKEASALDFDVSNNHIYWTDVSLKTISRAFMNGSSVEHVIEFGLDYPEGMAVDWMGKNLYWADTGTNRIEVARLDGQFRQVLVWRDLDNPRSLALDPTKGYIYWTEWGGKPRIVRAFMDGTNCMTLVDKVGRANDLTIDYADQRLYWTDLDT-NMIESSNMLGQER-MVIADDLPYPFGLTQYSDYIYWTDWNLHSIERADKTSGRNRTLIQGHLDFVMDILVFHSSRQDGLNDCVHSNGQCGQLCLAIPG--GHRCGCASHYTLDPSSRNCSPPSTFLLFSQKFAISRMIPDDQLSPDLVLPLHGLRNVKAINYDPLDKFIYWVDGR-QNIKRAKDDGTQPSMLTSPSQSLSPDRQPHDLSIDIYSRTLFWTCEATNTINVHRLDGDAMGVVLRGDRDKPRAIAVNAERGYMYFTNMQDHAAKIERASLDGTEREVLFTTGLIRPVALVVDNALGKLFWVDADLKRIESCDLSGANRLTLEDANIVQPVGLTVLGRHLYWIDRQQQMIERVEKTTGDKRTRVQGRVTHLTGIHAVEEVSLEEFSAHPCARDNGGCSHICIAKGDGTPR----CSCPVHLVLLQNLLTCGEPPTCSPDQFACTT-------GEIDCIPGAWRCDGFPECADQSDEEGCPVCSASQFPCARGQCVDLRLRCDGEADCQDRSDEANCDAVCLPNQFRCTS-GQCVLIKQQCDSFPDCADGSDE---LMCEINKPPSDDIPAHSSAIGPVIGIILSLFVMGGVYFVCQRVMCQRYTGASGPFPHEYVGGAPHVPLNFIAPGGSQHGPFPGIPCSKSVMSSMSLVGGRGS-VPLYDRNHVTGASSSSSSSTKATLYPPILNPPPSPATDPSLYNVDVFYSSGIPATARPYRPYVIRGMAPPTTPCSTDVCDSDYSTSRWKSSK----------------YYLDLNSDSDPYPPPPTPHSQYLS-----AEDSCPPSPGTERS-YCHLFPPPPSPCTDSS----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75197-1", "uniprot_id": "LRP5_HUMAN", "id": "O75197-1", "name": "Low-density lipoprotein receptor-related protein 5", "aln": "------------------------------MEAAPPGPPWPLLLLLLLLLALCG--------------CPAPAAASP----------LLLFANRRDVRLVDAG--GVKLESTIVVSGLEDAAAVDFQFSKGAVYWTDVSEEAIKQTYLNQTG--------AAVQNVVISGLVSPDGLACDWVGKKLYWTDSETNRIEVANLNGTSRKVLFWQDLDQPRAIALDPAHGYMYWTDWGETPRIERAGMDGS--TRKIIVDSDIYWPNGLTIDLEEQKLYWADAKLSFIHRANLDGSFRQKVVEGSLTHPFALTLSGDTLYWTDWQTRSIHACNKRTGGKRKEILSALYSPMDIQVLSQERQPFFHTRCEEDNGGCSHLCLLSPSEPFYTCACPTGVQLQDNGRTCKAGAEEVLLLARRTDLRRISLDTPDFTDIVLQVDDIRHAIAIDYDPLEGYVYWTDDEVRAIRRAYLDGSGAQTLVNTEINDPDGIAVDWVARNLYWTDTGTDRIEVTRLNGTSRKILVSEDLDEPRAIALHPVMGLMYWTDWGE-NPKIECANLDGQERRVLVNASLGWPNGLALDLQEGKLYWGDAKTDKIEVINVDGTKRRTLLEDKLPHIFGFTLLGDFIYWTDWQRRSIERVHKVKAS-RDVIIDQLPDLMGLKAVNVAKVVGTNPCADRNGGCSHLCFFTPHATRCGCPIGLELLSDMKTCIVPEAFLVFTSRAAIHRISLETN---NNDVAIPLTGVKEASALDFDVSNNHIYWTDVSLKTISRAFMNGSSVEHVVEFGLDYPEGMAVDWMGKNLYWADTGTNRIEVARLDGQFRQVLVWRDLDNPRSLALDPTKGYIYWTEWGGKPRIVRAFMDGTNCMTLVDKVGRANDLTIDYADQRLYWTDLDT-NMIESSNMLGQER-VVIADDLPHPFGLTQYSDYIYWTDWNLHSIERADKTSGRNRTLIQGHLDFVMDILVFHSSRQDGLNDCMHNNGQCGQLCLAIPG--GHRCGCASHYTLDPSSRNCSPPTTFLLFSQKSAISRMIPDDQHSPDLILPLHGLRNVKAIDYDPLDKFIYWVDGR-QNIKRAKDDGTQPFVLTSLSQGQNPDRQPHDLSIDIYSRTLFWTCEATNTINVHRLSGEAMGVVLRGDRDKPRAIVVNAERGYLYFTNMQDRAAKIERAALDGTEREVLFTTGLIRPVALVVDNTLGKLFWVDADLKRIESCDLSGANRLTLEDANIVQPLGLTILGKHLYWIDRQQQMIERVEKTTGDKRTRIQGRVAHLTGIHAVEEVSLEEFSAHPCARDNGGCSHICIAKGDGTPR----CSCPVHLVLLQNLLTCGEPPTCSPDQFACAT-------GEIDCIPGAWRCDGFPECDDQSDEEGCPVCSAAQFPCARGQCVDLRLRCDGEADCQDRSDEADCDAICLPNQFRCAS-GQCVLIKQQCDSFPDCIDGSDE---LMCEITKPPSDDSPAHSSAIGPVIGIILSLFVMGGVYFVCQRVVCQRYAGANGPFPHEYVSGTPHVPLNFIAPGGSQHGPFTGIACGKSMMSSVSLMGGRGG-VPLYDRNHVTGASSSSSSSTKATLYPPILNPPPSPATDPSLYNMDMFYSSNIPATARPYRPYIIRGMAPPTTPCSTDVCDSDYSASRWKASK----------------YYLDLNSDSDPYPPPPTPHSQYLS-----AEDSCPPSPATERS-YFHLFPPPPSPCTDSS----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QTJ4-1", "uniprot_id": "F1QTJ4_DANRE", "id": "F1QTJ4-1", "name": "", "aln": "------------------------------MELKPG---ALAMEILLLELLLCC--------------SLTVIRGSP----------LLLFANRRDVRLVDVE--VGRSESAVVVSDLEDAAAVDFLFSEGLIFWTDVSEEAIKQTYYNLSTNSMKEATLGKGQTVVVSGLDSPDGLACDWLGHKLYWTDSETNRIEVANLDGTSRKVLFWQDLDQPRAIALNPSHRYMYWTDWGEEPRIERAGMDGS--NRQIIVQKQIYWPNGLTIDLDEQKLYWADAKLSFIHRANLDGTSREAVVEGSLTHPFALTLYDETLYWTDWQTRSIHACNKHSGEKHREILNGIYSPMDIQVLGQERQPNIQTPCSERNGGCSHLCLLSPIPPFYSCACPTGVKLKEDGKTCRPGAEQVLLLARRTDLRRISLDLPDFTDIVLQVNDIRHAIAIDYDPVEGYVYWTDDELRAIRRARIDGSDAQTLITNEINHPDGIAVDWVARNLYWTDTGTDRIEVTRLNGTSRRVLISENLDEPRAIVLDPINGYMYWTDWGE-LPKIERANLDGTDRVVLLNTSLGWPNGLAIDYIAGKLYWGDAKTDKIEVINVDGTNRMTILEDKLPHIFGFTLLGEYIYWTDWQRRSIERVHIANST-REVIVEQLPDLMGLKATKVMEAEGTNGCAENNGGCSHLCFHRPQGLSCACPMGLELLSDLRTCVVPEAFLLFTNRADIRSISLGTN---SNDVPIPLTGVKEASALDFDVLENRIYWTDVSTKTISRAFMNGSSVEPVIEFGLDYPEGMAVDWMGRNLYWADTGTNRIEVARLDGQYRQVLVCKDLDNPRSLALDPANGYMYWTEWGGRPRIARAHMDGSNIVTLVDKVGRANGLTIDYIDQRLYWTDLDT-CMIESTNMQGLQR-EIVADDLPHPFGLTQYRDYIYWTDWNLRSIERADKRSGLNRTVVQGHLEYVMDILVFHSSRQDGANDCSQNNGQCAHLCLASPS--GAQCRCASHYTLEANGRNCSSPSSFLLFSQKSSISRMVLGEQ-SPDMILPIHVMKNLRAISFDPLERLVYWVDGR-QNIRRSRDDGTQASTVMTPNSDHP--KQPHDLSLDPYSRTVYWTCETTNTINIHRMDGHIIGEVLKDDVDKPRAIVVNAEKGYMYFTTVQERSAKIEGASLDGTERESLFTTSLIRPVALALDNKLGKLFWVDADLKRIESSDLSGANRIVLQDSNILQPVGLTVLGDHLYWIDKQQQMIERVDKLTGEKRTRIQGRLQYLTGIHAVQYMETDEFATHPCSRDNGGCSHICIAKGDGTPR----CSCPMHLVLLQNLLSCGEPPTCSSEQFTCAT-------GEIDCIPMAWRCDGIAECADNSDEMNCPICSKLQFQCDKGQCVDIQVRCNGEPDCADGSDEQDCETICLSNQFRCGN-SQCILKKQQCDSFPDCTDESDE---RFCDFP-PPPNDLPRHTSTIGPVIGIILSVFVMGGMCFVCQRVVCRHYKGPNGGFPHEYISGTPHVPLNFIAPTNSQHG--KGISCGKSMMSSVSLMGSSSSGAPLYDRNHVTGASSSSSSSTKGAFYPQMLNPPPSPATDRSLYNAEVFYSSNSPSTTRSYRPYLMRGVAPPTTPCSTDVCDSDYTTSRWKSNK----------------YYMDLNSDSDPYPPPPTPRSQYMS-----AEESCPPSPSTERS-YFHLCPPPPSPCTDSS----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z9D7-1", "uniprot_id": "A1Z9D7_DROME", "id": "A1Z9D7-1", "name": "Low-density lipoprotein receptor-related protein", "aln": "MALEPYTKSAEIEPQLCQVIDNNEDVTTKATKCTKSNSGVGWRQMLIGFLLICFGISNSWQYKNVHMPSSSSLIASPPASAFVNTPATLLFTTRHDIQVANITRPTGGPQIDVIVRDLAEAMAIDFYYAKNLVCWTDSGREIIECAQTNSSALQPLLR--APKQTVISTGLDKPEGLAMDWYTDKIYWTDGEKNRIEVATLDGRYQKVLFWTDLDQPRAVAVVPARKLLIWTDWGEYPKIERASMDGDPLSRMTLVKEHVFWPNGLAVDLKNELIYWTDGKHHFIDVMRLDGSSRRTIVN-NLKYPFSLTFYDDRLYWTDWQRGSLNALDLQTR-ELKELIDTPKAPNSVRAWDPSLQPYEDNPCAHNNGNCSHLCLLATNSQGFSCACPTGVKLIS-ANTCANGSQEMMFIVQRTQISKISLDSPDYTIFPLPLGKVKYAIAIDYDPVEEHIYWSDVETYTIKRAHADGTGVTDFVTSEVRHPDGLALDWLARNLYWTDTVTDRIEVCRLDGTARKVLIYEHLEEPRAIAVAPSLGWMFWSDWNERKPKVERASLDGSERVVLVSENLGWPNGIALDIEAKAIYWCDGKTDKIEVANMDGSGRRVVISDNLKHLFGLSILDDYLYWTDWQRRSIDRAHKITGNNRIVVVDQYPDLMGLKVTRLREVRGQNACAVRNGGCSHLCLNRPRDYVCRCAIDYELANDKRTCVVPAAFLLFSRQEHIGRISIEYNEGNHNDERIPFKDVRDAHALDVSVAERRIYWTDQKSKCIFRAFLNGSYVQRIVDSGLIGPDGIAVDWLANNIYWSDAEARRIEVARLDGSSRRVLLWKGVEEPRSLVLEPRRGYMYWTESP-TDSIRRAAMDGSDLQTIVAGANHAAGLTFDQETRRLYWATQSRPAKIESADWDGKKRQILVGSDMDEPYAVSLYQDYVYWSDWNTGDIERVHKTTGQNRSLVHSGMTYITSLLVFNDKRQTGVNPCKVNNGGCSHLCLAQPGRRGMTCACPTHYQLAKDGVSCIPPRNYIIFSQRNCFGRLLPNTTDCPNIPLPVSG-KNIRAVDYDPITHHIYWIEGRSHSIKRSLANGTKVSLLANSG-------QPFDLAIDIIGRLLFWTCSQSNSINVTSFLGESVGVIDTGDSEKPRNIAVHAMKRLLFWTDVGSHQAIIR-ARVDGNER-VELAYKLEGVTALALDQQSDMIYYAHG--KRIDAIDINGKNKKTLVSMHISQVINIAALGGFVYWLD-DKTGVERIT-VNGERRSAELQRLPQITDIRAVWTPDPKVLRNHTCMHSRTKCSHICIASGEGIARTRDVCSCPKHLMLLEDKENCGAFPACGPDHFTCAAPVSGISDVNKDCIPASWRCDGQKDCPDKSDEVGCPTCRADQFSCQSGECIDKSLVCDGTTNCANGHDEADCCKR--PGEFQCPINKLCISAALLCDGWENCADGADESSDICLQRRMAPATDKRAFMILIGATMITIFSIVYL--------LQFCRTRIGKSRTEPKDDQATDPLSPSTLSK---SQRVSKIASVADAVRMSTLNSRNSMNS----YDRNHITGASSSTTNGSSMVAYP--INPPPSPATR----------------SRRPYRHYKIINQPPPPTPCSTDICDESDSNYTSKSNSNNSNGGATKHSSSSAAACLQYGYDSEPYPPPPTPRSHYHSDVRIVPESSCPPSPSSRSSTYFSPLPPPPSPVQSPSRGFT", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : * : . .** ***:.*:*:::.: : ::. .* :* *:** :::. : *** ..* *: : * : . *.:: :** .*:*** ** .*:****.*.******.*:* :***** *******:*: *:: : ****** *:****.***. .* :*...::*****::**.:: :**:*.* **. .***: *. :*: .*.:**:**: .: ******* *::* : : : :*::. :* .::. . . ** .. * . **.*******:. ::*******:* . ..** *:::::::.:**:: :**** **:* : * :..:::********:* ::**:* * :*:** **:.. ::..*:..***:*:**:********* ****** **:**:*::*: *.*:*****.: * * *:*:**.* **:* *.*** :* **:. .******:*:* :** *.******* *:**: * .::.*:* *:**:::*.:::**********:*.* ... * *:::* *******...: :. * * ** ********: *: * *.:. ** .* :**::* ***:*: : * **: * ** **:..*::* ***..* :.:***** . * * ***:*** *: ::: ** *:*:****:..*:**:*: :.*********. *:**: :.:::****.*:* .**:**** * ** ***:: *:* ..:* .**:* :****: . ***:: * :* ::..*: *:.:: * **:**:*** .***..* :* **::::. : :: .:***:..** * * * .** *.:**** *. * * *.:** * .. .* .* .:::***: .:.*:: . .*:: **: :*::*:.:**: : :**::** :.*:*: :**: : . . **.**::* .* ::***. :*:**: : *. :* : .* ::** *.*:* : :::* : .: * *. * :**.** :: * .**.:*: . :::... ***:: *:.* *: .* . :* * :.:: ** .:**:* :: :**: .*::*: *: :*.*:** . . : *.* :.. *******.*:* .* **** **:**:: .** *:*..::*:*:: : **** :***** :* *:*** .** * ** * *:*:* : *:* .:* : ** :* ..:*:* *: **.: :* * :** : .*. * . **..: *:*:. : .*: * . *:: . * * .: **: . .. **::. .. .. *****:******::..:. . ** :******** : *.** * : . .**.******:**.. : *:.. :: . **:********:*:* * .*.****** :. * * ****** ..* ", "identical_positions": 628, "similar_positions": 513, "identity": "36.24%" }, { "cls_id": "homologset.agr.MGI:1278317", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8M9PB91-1", "uniprot_id": "A0A8M9PB91_DANRE", "id": "A0A8M9PB91-1", "name": "", "aln": "MTNNTTFSFLSNSKISIHYEKTT------VDMVFYTIVILLGTTGNSVVIWVAGFHMKSNVTKVWLVNLAVADLIFCLTRISSLISKVFFDYWPFGVFLCKFNGFIKYANMFCSVFLLAVISVDRALCIWHPFFTRERRTVCAARVVSVGVWIVAVIFSSPYFVYRQVFPGKNNLSHCSLKVNGSSETG-------ISTKYVYYFIRFICGFLLPFLIIFICYTLAAIGIRRSRLSRKAKPLRILAVLVCAFFLCWAPYHFLGLVK--LVNKDNEVVKIGWNMASN---LAYFNSCINPILYFFMGLDVSRRCNQSLSGIFRRALMEEGQSLSQQGIGEDISNSFLKTIGVECETKV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A4FUQ5-1", "uniprot_id": "FPRS4_MOUSE", "id": "A4FUQ5-1", "name": "Formyl peptide receptor-related sequence 4", "aln": "--MEVNISMPLNGSEVVFYDSTTSRVLWILSLVVLFITFVLGVLGNGLVIWVAGFQMAHTVTTVSYLNLALSDLSFMATLPLHIISMVMRGKWLFGWFLCKLVHIIANINLFVSIFLITLIAMDRCICVLCPVWSQNHRTVSLARKVVLGAWIFALLLTLPHFLFLTTVRDARGDVYCISKFESWVATSEEQLKVSVIAATASGIINFIIGFSMPMSFIAICYGLMAAKICRRGFVNSSRPLRVLTAVAVSFFVCWFPFQLIMLLGNIFNNETLSIIHMLVNPANT---LASFNSCLNPILYVFLGQEFRDRLIYSLYASLERALRED-----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M6YSE5-1", "uniprot_id": "A0A8M6YSE5_DANRE", "id": "A0A8M6YSE5-1", "name": "", "aln": "-MENSSFGLKNLTGNSTDKNAVEDKGFKIFLACIFFSTVSVGLIGNGLVIFLAGCRMKMTFNSIWFLNLAIADFIFILFSITNASLTLSK---QHSVVKEYFLFIATSINLFASIWSLVVISLDRCLCTWMAVWAQNNRTLRKARIICIIIWVSSIGYILPYFTVFNITG------------------------------TILVTYGFIVVFLIPFLIIASSYIAIGVKINRLKKRKQLRSYRLIITVILTFFICSFPHNVCWIWMVWAKNNNWTLTDQFWKLFVFTFYLMNLNSSLNPFLYVFMCDDFKKKLKQSLVLVLETAFAEDHLDIKEMRHTKMINRQNKPHLNC------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .:.: : . . . .. :* **.:**::** :* ....: :***::*: * : .. . : : *:* *:: :.:*::**.:* ..::::.**: ** : : *: :: *:* ** * :*: :* .* . * * .. :. *:: .: :**:* *.:. : *: : . : * :**.:**:**.*: :. : ** :. *: *: ", "identical_positions": 53, "similar_positions": 92, "identity": "14.85%" }, { "cls_id": "homologset.agr.MGI:1278318", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LY43-1", "uniprot_id": "A0ABK0LY43_RAT", "id": "A0ABK0LY43-1", "name": "", "aln": "--MEANISMPRNGSEVGFYDSTTSTVLWILSLVVLCITFVLGVLGNGLVIWVSEFRMAHTVTTVCYLNLALSDFSFMATLPLQIISMVMRGKWLFGWFLCKLVHIIANINLFVSIFLITLIAMDRCTCVLHPVWSQNHRTVSLARKVVVGAWIFALLLTLPHFLFLTTVKDARGEVHCISKFESWVATPEEQLKVSITATTASGIINFIIGFSMPMSFIAICYGLMAVKICRRGFVKSSRPLRVLTAVAVSFFVCWFPFQLIMLLGNILNKETLSIIHILVNPANT---LASFNSCLNPILYVFLGQEFRDRLMHSLSASLERALRED-----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88537-1", "uniprot_id": "FPRS3_MOUSE", "id": "O88537-1", "name": "Formyl peptide receptor-related sequence 3", "aln": "--MEANSSIPLNGSEVVFYDSTTSRVLWILSVIVLSITFVLGVLGNGLVIWVAGFRMAHTVTTICYLNLALGDFSFMVTLPLHIISMVMKGKWLFGWFLCKFVLSIVHINLFVSVFLITLIAMDRCTCVLHPVWVQNHRTVSLARKVIVGAWILSLLLTLPHFLFLTTVRDARGEVHCTCNFESVVANPEEQLKVSITVSTATGIISFIIGFSLPMSFIAVCYGLMAAKICRKGFLNSSRPLRVLTAVAISFFMCWFPFQLIILLGNIWNKETPSSIHILLNPAST---LASFNSCLNPILYVFLGQEFREKLIYSLSASLERALREDSVLSSGKSSNFSSCPADSEL---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M9PB91-1", "uniprot_id": "A0A8M9PB91_DANRE", "id": "A0A8M9PB91-1", "name": "", "aln": "MTNNTTFSFLSNSKISIHYEKTT------VDMVFYTIVILLGTTGNSVVIWVAGFHMKSNVTKVWLVNLAVADLIFCLTRISSLISKVFFDYWPFGVFLCKFNGFIKYANMFCSVFLLAVISVDRALCIWHPFFTRERRTVCAARVVSVGVWIVAVIFSSPYFVYRQVFPGKNNLSHCSLKVNGSSETG-------ISTKYVYYFIRFICGFLLPFLIIFICYTLAAIGIRRSRLSRKAKPLRILAVLVCAFFLCWAPYHFLGLVK-LVNKDNE-VVKIGWNMASN---LAYFNSCINPILYFFMGLDVSRRCNQSLSGIFRRALMEEGQSLSQQGIGEDISNSFLKTIGVECETKV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M6YSE5-1", "uniprot_id": "A0A8M6YSE5_DANRE", "id": "A0A8M6YSE5-1", "name": "", "aln": "-MENSSFGLKNLTGNSTDKNAVEDKGFKIFLACIFFSTVSVGLIGNGLVIFLAGCRMKMTFNSIWFLNLAIADFIFILFSITNASLTLSK---QHSVVKEYFLFIATSINLFASIWSLVVISLDRCLCTWMAVWAQNNRTLRKARIICIIIWVSSIGYILPYFTVFNITG------------------------------TILVTYGFIVVFLIPFLIIASSYIAIGVKINRLKKRKQLRSYRLIITVILTFFICSFPHNVCWIWMVWAKNNNWTLTDQFWKLFVFTFYLMNLNSSLNPFLYVFMCDDFKKKLKQSLVLVLETAFAEDHLDIKEMRHTKMINRQNKPHLNC------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::. .: : . . . .. :* **.:**::: :* ....: :***:.*: * : .. . : *:* *:: :.:*::**. * ..: ::.**: ** : : *: :: *:* ** * :*: :* .* . * * .. :. *:: .: :**:* *.:. : :::. . : * :**.:**:**.*: :. : ** :. *: *: ", "identical_positions": 50, "similar_positions": 92, "identity": "14.01%" }, { "cls_id": "homologset.agr.MGI:1278319", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AM80-1", "uniprot_id": "A0A8I6AM80_RAT", "id": "A0A8I6AM80-1", "name": "", "aln": "--MEANYSVPLNVSEVVVYDSTISRVLWILSMVVLSITFVLGVLGNGLVIWVAGFRMVHTVTTTCYLNLALADFSFTATLPFFVISTAMKEKWPFGWFLCKLVHIVVDINLFGSVFLIALIALDRCICVLHPVWAQNHRTVSLARKVVVGPWILALILTLPIFVFMTTVRVPGGNVYCTFNYASWGKTVEEVLDVANTCETVRGTIRFVIGFTMPMSIVAICYGLIAVKIHRRALVNSSRPLRVLTAVVVSFFICWFPFQLVALLGTIWFKELLFNTRYGILKMWVNPTSSLAYFNSCLNPMLYVFMGQDFRERLIHSLPSSLERALSEDCGQTS-----DTGTNSALPPADIEIKAI-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88536-1", "uniprot_id": "FPR2_MOUSE", "id": "O88536-1", "name": "Formyl peptide receptor 2", "aln": "--MESNYSIHLNGSEVVVYDSTISRVLWILSMVVVSITFFLGVLGNGLVIWVAGFRMPHTVTTIWYLNLALADFSFTATLPFLLVEMAMKEKWPFGWFLCKLVHIVVDVNLFGSVFLIALIALDRCICVLHPVWAQNHRTVSLARKVVVGPWIFALILTLPIFIFLTTVRIPGGDVYCTFNFGSWAQTDEEKLNTAITFVTTRGIIRFLIGFSMPMSIVAVCYGLIAVKINRRNLVNSSRPLRVLTAVVASFFICWFPFQLVALLGTVWFKETLLSGSYKILDMFVNPTSSLAYFNSCLNPMLYVFMGQDFRERFIHSLPYSLERALSEDSGQTS-----DSSTSSTSPPADIELKAP-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P25090-1", "uniprot_id": "FPR2_HUMAN", "id": "P25090-1", "name": "N-formyl peptide receptor 2", "aln": "--METNFSTPLNEYEEVSYESAGYTVLRILPLVVLGVTFVLGVLGNGLVIWVAGFRMTRTVTTICYLNLALADFSFTATLPFLIVSMAMGEKWPFGWFLCKLIHIVVDINLFGSVFLIGFIALDRCICVLHPVWAQNHRTVSLAMKVIVGPWILALVLTLPVFLFLTTVTIPNGDTYCTFNFASWGGTPEERLKVAITMLTARGIIRFVIGFSLPMSIVAICYGLIAAKIHKKGMIKSSRPLRVLTAVVASFFICWFPFQLVALLGTVWLKEMLFYGKYKIIDILVNPTSSLAFFNSCLNPMLYVFVGQDFRERLIHSLPTSLERALSEDSAPTN-----DTAANSASPPAETELQAM-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PB91-1", "uniprot_id": "A0A8M9PB91_DANRE", "id": "A0A8M9PB91-1", "name": "", "aln": "MTNNTTFSFLSNSKISIHYEKTT------VDMVFYTIVILLGTTGNSVVIWVAGFHMKSNVTKVWLVNLAVADLIFCLTRISSLISKVFFDYWPFGVFLCKFNGFIKYANMFCSVFLLAVISVDRALCIWHPFFTRERRTVCAARVVSVGVWIVAVIFSSPYFVYRQVFPGKNNLSHCSLKVNGSSETG-------ISTKYVYYFIRFICGFLLPFLIIFICYTLAAIGIRRSRLSRKAKPLRILAVLVCAFFLCWAPYHFLGLV-------KLVNKDNEVVKIGWNMASNLAYFNSCINPILYFFMGLDVSRRCNQSLSGIFRRALMEEGQSLSQQGIGEDISNSFLKTIGVECETKV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M6YSE5-1", "uniprot_id": "A0A8M6YSE5_DANRE", "id": "A0A8M6YSE5-1", "name": "", "aln": "-MENSSFGLKNLTGNSTDKNAVEDKGFKIFLACIFFSTVSVGLIGNGLVIFLAGCRMKMTFNSIWFLNLAIADFIFIL---FSITNASLTLSKQHSVVKEYFLFIATSINLFASIWSLVVISLDRCLCTWMAVWAQNNRTLRKARIICIIIWVSSIGYILPYFTVFNITG------------------------------TILVTYGFIVVFLIPFLIIASSYIAIGVKINRLKKRKQLRSYRLIITVILTFFICSFPHN-VCWIWMVWAKNNNWTLTDQFWKLFV-FTFYLMNLNSSLNPFLYVFMCDDFKKKLKQSLVLVLETAFAEDHLDIK-----EMRHTKMINRQNKPHLNC-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::.:. : . . . .. :* **.:**::** :* .... :***:**: * : . : .. . : : *:* *:: : .*::**.:* ..::::.**: * : : *: :: * * *: * :*: *: .* . *.: .. :. *:: .:: :**:* *.: : : . .: : * :**.:**:**.*: *. .: :** :. *: *: . : .. ", "identical_positions": 51, "similar_positions": 99, "identity": "14.21%" }, { "cls_id": "homologset.agr.MGI:1278321", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4ADG5-1", "uniprot_id": "D4ADG5_RAT", "id": "D4ADG5-1", "name": "Enhancer of polycomb homolog", "aln": "-------------------------------------------------MSKLSFRARALDAAKPLPIYRGKDMPDLNDCVSINRAVPQMPTGMEKEEESEHHLQRAISAQQVFREKKESMVIPVPEAESNVN-YYNRLYKGEFKQPKQFIHIQPFNLDNEQPDYDMDSEDETLLNRLNRKMEIKPLQFEIMIDRLEKASSNQLVTLQEAKLLLNEDDYLIKAVYDYWVRKRK-NCRGPSLIPQIKQEKRDGSTNNDPYVAFRRRTEKMQTRKNRKNDEASYEKMLKLRREFSRAITILEMIKRREKTKR-ELLHLTLEVVEKRYHLGDYGGEILNEVKVNRS--------------------------------------------EKELYASPATLHNGNHHKVQECKTKHPHHLSLKEEASDVVRQKKKHPKKPKAEAVLAPPQPTPETVPVINKSDIKQYDFQ-----------------------SSDEDEFPQVPSPASEPEEENDPDGPCAFRRRAGCQYYAPRLDQANNHPCESSE----LADLDKLRYKHCLTTLTVPR-RCIGFARRRIGRGGRVIMDRISTEHD--------------------PVLKQIDPEMLNGLSSSSQTIDFS-----------------------------------------------------------SNFSRTNASSKPCENRLSLSEILSNIRSCRLQCFQPRLLNVQD-----------------------------------------------------------------------------------------------------------------------------------IDSEECTSRKPGQTVSSKRVSAASVALLNTSKNGISVTGGITEEQFQTHQQQLAQMQ------------------------------------------------RQQLAQLQQKQQSQHSSQQTHPKAQGSSTSDCMS------------------------------------------------------------------------------------KTLDSASAHFAASAVVSAPVPSRSEGSKEQ------------------------------------------------------------------------------------------------NTGHNNMNGVVQPSGPSKTLYSTNMALSSS----PGISAVQLVRTVGHTTTNHLIPALCTSSPQTLPMNNSCLTN---------------------AVHLNNVSVVSPVNVHINTRTSAP--------SPTALKLATVAASMDRVPKVTPSSAISSIARENHEPERLGLNGIAETTVAMEVT------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6AJU0-1", "uniprot_id": "A0A8I6AJU0_RAT", "id": "A0A8I6AJU0-1", "name": "Enhancer of polycomb homolog", "aln": "-------------------------------------------------MSKLSFRARALDAAKPLPIYRGKDMPDLNDCVSINRAVPQMPTGMEKEEESEHHLQRAISAQQVFREKNESMVIPVPEAESNVN-YYNRLYKGEFKQPKQFIHIQPFNLDNEQPDYDMDSEDETLLNRLNRKMEVKPLQFEIMIDRLEKASSNQLVTLQEAELLLNEDDYLIKAVYDYWVRKSK-NCRGPSLIPQIKQEKRDGSTNNDPYVAFRRRTEKMQTRKNRKNDEASYEKMLKLRREFSRAITILEMIKRREKTKR-ELLHLTLEVVEKRYHLGDYGGEILNEVKVNRS--------------------------------------------EKELYASPATLHNGNHHKVQECKTKHPHHLSLKEEASDVVRQKKKHPKKPKAEAVLAPPQPTPETVPVINKSDIKQYDFQ-----------------------SSDEDEFPQVPSPSSEPEEENDPDGPCAFRRRAGCQYYAPRLDQANNHPCKSSE----LADLDKLRYKHCLTTLTVPR-RCIGFARRRIGRGGRVIMDRISTEHD--------------------PVLKQIDPEMLNGLSSSSQTIDFS-----------------------------------------------------------SNFSRTNASSKPCENRLSLSEILSNIRSCRLQCFQPRLLNVQD-----------------------------------------------------------------------------------------------------------------------------------IDSEEYTSRKPGQTVSSKRVSAASVALLNTSKNGISVTGGITEEQFQTHQQQLAQMQ------------------------------------------------RQQLAQLQQKQQSQHSSQQTHPKAQGSSTSDCMS------------------------------------------------------------------------------------KTLDSASAHFAASAVVSAPVPSRSEGSKEQ------------------------------------------------------------------------------------------------NTGHNNMNGVVQPSGPSKTLYSTNMALSSS----PGISAVQLVRTVGHTTTNHLIPALCTSSPQTLPMNNSCLTN---------------------AVHLNNVSVVSPVNVHINTRTSAP--------SPTALKLATVAASMDRVPKVTPSSAISSIARENHEPERLGLNGIAETTVAMEVT------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C0I4-1", "uniprot_id": "EPC2_MOUSE", "id": "Q8C0I4-1", "name": "Enhancer of polycomb homolog 2", "aln": "-------------------------------------------------MSKLSFRARALDAAKPLPIYRGKDMPDLNDCVSINRAVPQMPTGMEKEEESEHHLQRAISAQQVFREKKESMVIPVPEAESNVN-YYNRLYKGEFKQPKQFIHIQPFNLDNEQPDYDMDSEDETLLNRLNRKMEIKPLQFEIMIDRLEKASSNQLVTLQEAKLLLNEDDYLIKAVYDYWVRKRK-NCRGPSLIPQIKQEKRDGSTNNDPYVAFRRRTEKMQTRKNRKNDEASYEKMLKLRREFSRAITILEMIKRREKTKR-ELLHLTLEVVEKRYHLGDYGGEILNEVKVNRS--------------------------------------------EKELYASPATLHNGNHHKVQECKTKHPHHLSLKEEASDVVRQKKKYPKKPKAEAGIAPQQPTPETLPVINKSDIKQYDFQ-----------------------SSDEDEFPQVLSPASEAEEENDPDGSCAFRRRAGCQYYAPRLDQANNHMCENSE----LADLDKLRYKHCLTTLTVPR-RCIGFARRRIGRGGRVIMDRISTEHD--------------------PVLKQIDPEMLNGFSSSSQTIDFS-----------------------------------------------------------SNFSRTNASSKPCENRLSLSEILSNIRSCRLQCFQPRLLNVQD-----------------------------------------------------------------------------------------------------------------------------------IDSEECTSRKPGQTVSSKRVSAASVALLNTSKNGISVTGGITEEQFQTHQQQLVQMQ------------------------------------------------RQQLAQLHQKQQSQHSSQQTHPKAQGSSTSDCMS------------------------------------------------------------------------------------KTLDSASAHFAASAVVSAPVPSRSEGSKEQ------------------------------------------------------------------------------------------------NTGHNNMNGVVQPSGPSKTLYSTNMALSSS----PGISAVQLVRTVGHTTTNHLIPALCTSSPQTLPMNNSCLTN---------------------AVHLNNVSVVSPVNVHINTRTSAP--------SPTALKLATVAASMDRVPKVTPSSAISSIARENHEPERLGLNGLAETTVAMEVT------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q52LR7-1", "uniprot_id": "EPC2_HUMAN", "id": "Q52LR7-1", "name": "Enhancer of polycomb homolog 2", "aln": "-------------------------------------------------MSKLSFRARALDAAKPLPIYRGKDMPDLNDCVSINRAVPQMPTGMEKEEESEHHLQRAISAQQVFREKKESMVIPVPEAESNVN-YYNRLYKGEFKQPKQFIHIQPFNLDNEQPDYDMDSEDETLLNRLNRKMEIKPLQFEIMIDRLEKASSNQLVTLQEAKLLLNEDDYLIKAVYDYWVRKRK-NCRGPSLIPQIKQEKRDGSTNNDPYVAFRRRTEKMQTRKNRKNDEASYEKMLKLRREFSRAITILEMIKRREKTKR-ELLHLTLEVVEKRYHLGDYGGEILNEVKISRS--------------------------------------------EKELYATPATLHNGNHHKVQECKTKHPHHLSLKEEASDVVRQKKKYPKKPKAEALITSQQPTPETLPVINKSDIKQYDFH-----------------------SSDEDEFPQVLSPVSEPEEENDPDGPCAFRRRAGCQYYAPRLDQAN-HSCENSE----LADLDKLRYRHCLTTLTVPR-RCIGFARRRIGRGGRVIMDRISTEHD--------------------PVLKQIDPEMLNSFSSSSQTIDFS-----------------------------------------------------------SNFSRTNASSKHCENRLSLSEILSNIRSCRLQCFQPRLLNLQD-----------------------------------------------------------------------------------------------------------------------------------SDSEECTSRKPGQTVNNKRVSAASVALLNTSKNGISVTGGITEEQFQTHQQQLVQMQ------------------------------------------------RQQLAQLQQKQQSQHSSQQTHPKAQGSSTSDCMS------------------------------------------------------------------------------------KTLDSASAHFAASAVVSAPVPSRSEVAKEQ------------------------------------------------------------------------------------------------NTGHNNINGVVQPSGTSKTLYSTNMALSSS----PGISAVQLVRTVGHTTTNHLIPALCTSSPQTLPMNNSCLTN---------------------AVHLNNVSVVSPVNVHINTRTSAP--------SPTALKLATVAASMDRVPKVTPSSAISSIARENHEPERLGLNGIAETTVAMEVT------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4KFP2-1", "uniprot_id": "A0A0B4KFP2_DROME", "id": "A0A0B4KFP2-1", "name": "Enhancer of polycomb-like protein", "aln": "-------------------------------------------------MSKLSFRARHLDPSKQMPIYLAEELPDLPEYSAINRAVPQMPSGMEKEEESEHHLQRAICTG---------LIIPTPEVLQTDQPFYDAYYPPDYKMPRQMIHMQPLGLDTEVPDYDMDSADEDWLSQQ-QRLELTELKFEQMMDRLEKSSGQTVVTLNEAKSLLNQDDETSISVYDYWLNKRL-KMQHP-LILTVKTESRPGASSNNPYLAFRRRTEKMQTRKNRKNDEASYEKMLKLRRDLQRATTILEMVRRREETKR-DHLKMTVNIFEKRVEMRDFNGAVYSELNSQYKNTRPAYNPLYTNQYSQGAAAVGTAGAILAALPTGLLPGGAGAAGNANVFGSASQYLNSSNLTMDAISGSGNGNSSRKEKRPYKKRKHKLPRDKQQHQQQQTQQHQQQQYLPASGGAGVSPAHHLPHHLHHLSRQQSASPAANDSIADSEEEDYFGAGAQNGNKLGSESEEETPFAFRRRSSCVYLPTRQRDGRYPWDSADEDMAPSGACSDAKYRYTLTSLNYPRPRCIGFARRRLGRGGRILLDRATTNFDDFWSQLDYTVMESVTVNKCRDKIKQRDPDQLCKPSSPPTVVDLVPAGKPVDGEHPVPELIKEEPSSDTEKPVAATESGRESKERELEEKFENDVDDEFVASDDENVSRLGIYSSAVTLPQSCADLRQKRRRLRRKKQQLRELNAAKRLKRSSEAVATAEDVQLEDEDTKPDLRPLPRAYLQRLALILGQKLKVEEDDNTEVSENVAPELLEMNDPEQLQPPRANHQQHHRSNHNNNNNTVLNNNNSSSSNVMNKDVSISEKINVIKQEAEELVGGKCEDQPVASTSAAAAAARAAEAAAAAEAASSTTTLAAPNPGPSLEEVAKTIKREMIDADDSNEPLSSIRTAAVMLSTQTSVSELMDDEAEDDVNLAQLSSIIRHTAVKKELEAQQHQQQVQHEQMQAARKMEEDEAAPCLNQLPDVIRLRNIRNSQVHARPKDLFVQAPVDEEFNADYMGGLSPTSSQRLDICNELLSEIRRDWLHFRPKTPTDELSDSQDCEVGKTCDSHAVDWTQDTPISVELNRLGKREAEESDSSSYFLSSGFKYRDLESDAQLLQTVQAQDYARGSSKSPNCSGSGSGSALEFNLSGGDSLNDINNLLGCDDEDDNHEHMLDNILQECAMDDPKALNQATNFWNGILDGEAAVDEVEMADQLLDCIDEKKSKVGAADTSKRAGRNRKARLIQAPVGSSAFTVCPTAETLKERELFFSQAPPVEVPPKEKTPAEVELPEVVVKETANLPVKVEAVEKPQSEVLPVAPQPQQLQPQAITLPTTQLINIPAQISTQKQHQQPQVTQLLNQFANAGPQIIARTEYGGGAAVGDIVTITPHTGSSPLPTLTAQQQLQHQLAQAQLRNVTVQQRQATPQNPNQNQNPQQQLLFQMQRDPSRSLTPLQAAGAGATGNHLIYTTSCGEIVTAGAAASASQKVTYAIQKAGVSSGGATTASIGPNTVITLSNVKVQNDDISSGGSGNSGSSVNIINTASGQQLAVHSIAGMQQQGQQQVQQVTTSTPLLVATPTRNNVQQQQQQLVQQQPIVWRQVSGTNTAVATTAVLSTTVDSSPKAVTNQILWTSRATQKRQLNGPENTDINKLLLNRKLPRKQQIQQQHQQIQLTKQQLQQLVQHEELDDLVATSTGNSGDQMETGDGLQQQQQQQQQQQQLQKLSKVIKMSQFPLLVSDVSLQQQQSVSGQAQQQQLKPNSAAAIAANHNYSLHPASTAIITAQATPQQANKIFLTSSNSGGGGSAGNFTIATASELQAAAAGQKLHYKELPNSNLKLNFVSSAGTGEQTQQVGATTVLLNKSQQQQQQQQHQKLKTLATTGNSQTGQGDKRVLYTSLLNVKPLQKNNSGQMQMQLGPGGLQQVLRGRLNNSAIITRTLPLGTTVNSTGGAVGPTTTTIRQLVTTNANNVSSQDGNLLSAKEVGKALTVEQVIASANNGGVVLPTSNNNNNNNGSGAGGNGGPLNSGVNATGAGGGGSTGAGVGGAGVTSTINRXDADGSGSNSXHRAQPLQVPNGPLLSLASTQTEAETQAVAISMPLADAHVALGQLLQQHHCSCTVCLVNKSELV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P43572-1", "uniprot_id": "EPL1_YEAST", "id": "P43572-1", "name": "Enhancer of polycomb-like protein 1", "aln": "MPTPSNAIEINDGSHKSGRSTRRSGSRSAHDDGLDSFSKGDSGAGASAGSSNSRFRHRKISVKQHLKIYLPNDLKHLDKDELQQREVVEIETGVEKNEEKEVHLHRILQMGSG--HTKHKDYIPTPDASMTWN-EYDKFYTGSFQETTSYIKFSATVEDCCGTNYNMDERDETFLNEQVNKGSSD----ILTEDEFEILCSSFEHAIHERQPFLSMDPESILSFEELKPTLIKSDMADFNLRNQLNHEIN---SHKTHFITQFDPVSQMNTRPLIQLIEKFGSKIYDYWRERKIEVNGYEIFPQLKFERPGEKEEIDPYVCFRRREVRHPRKTRRIDILNSQR-----------------------------------------LRALHQELKNAKDLALLVAKRENVSLNWINDELKIFDQRVKIKNLKRSLNISGEDDDLINHKRKRPTIVTVEQREAELRKAEL------------------------KRAAAAAAAAKAKNNKRNNQLEDKSSRLTKQQQQQLLQQQQQQQQNALKTENGK--QLANASSSSTSQPITSHVYVKLPSSKIPDIVLEDVDALLNSKEKNARK--------------------FVQEKMEKRKIEDADVFFNLTDDP----------------------------------------------------------FNPVFDMSLPKNFSTSNVPFASIASSKFQIDRSFYSSHLPEYLKG-----------------------------------------------------------------------------------------------------------------------------------------------ISDDIRIYDSNGRSRNKDNYNLDTKRIKKTELYDPFQENLEIHS--------------------------------------------------REYPIKFRKRVGRSNIKYVDRMPNFTTSSTKS---------------------------------------------------------------------------------------ACSLMDFVDFDSIEKEQYSREGSNDTD--------------------------------------------------------------------------------------------------SINVYDSKYDEFVRLYDKWKYDSPQNEY-----GIKFSDEPARLNQISNDTQVIRFGTMLG---TKSYEQLREA--------------------TIKYRRDYITRLKQKHIQHLQQQQ---------QQQQQQQQQAQQQKQKSQNNNSNSSNSLKKLNDSLINSEAKQNSSITQKNSS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: ** * :. : : ** ::: .* . :* * :: :*:**:**.* **:* : **.*:. . : *: * .:: . . *::.. * .:*:**. ** *.. .: . *.:* ... :::* : :*. * :. : . * :: * . : : ::: ..:*:** : * .*: . *: . . *:. : : : : .: : :* .: . :: . : .. : . . :: . :: . : : : :.. . . .: .:. : . : :: : : . . . .. :*: : . :. : . :: .: .. . :: : : . * . . . .. . :.: .. . . : : . . : .. . * .. :.:: . . : ::: :.. : : :: . . .:. :. : . * :. : : . : : .: . : . . * : :. . : : :: : * . . .: : :. : :. ", "identical_positions": 52, "similar_positions": 231, "identity": "2.41%" }, { "cls_id": "homologset.agr.MGI:1278322", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8C9X6-1", "uniprot_id": "EPC1_MOUSE", "id": "Q8C9X6-1", "name": "Enhancer of polycomb homolog 1", "aln": "-------------------------------------------------MSKLSFRARALDASKPLPVFRCEDLPDLHEYASINRAVPQMPTGMEKEEESEHHLQRAISAQQVYGEKRDNMVIPVPEAESNIAYYESIYPGEFRMPKQLIHIQPFSLDAEQPDYDLDSEDEVFVNKLKKKMDICPLQFEEMIDRLEKGSGQ------------QPVSLQEAKLLLKEDDELIREVYEYWIKKRKTCRGSSLIPLVKQEKRDGSSTNDPYVAFRRRTEKMQTRKNRKNDEASYEKMLKLRRDLSRAVTILEMIKRREKSKRELLHLTLEIMEKRYNLGDYSGEIMSEVMAQRQPVKPTY-----------------------------------------------------AIPIIPITNS----SQFKHQDATDSKEFKVNKQDKADLIRPKRKYEKKPKVLPPSAAA-------PQQQSPAALPGFSAKDLNQYDFPSSDEEPLSQVLSGSSEAEEENDPDGPFAFRRKAGCQYYAPHLDQTGNWPWTSPKD-----GGLGDVRYRYCLTTLTVP-QRCLGFARRRVGRGGRVVLDRAHSDYDSMFHHLDLDMLSSPQPSPVNQFANTSEPNTSDRSSS-----KDLSQILVDIKSCRWRHFRPRTPSLPDSDSGE----------------------------------------------------LSSRKLHRSISRAGAAQPGAHTCSTSTQNRSSSGSAHCAFTAEQY----------QQHQQQLALMQQQQLAQTQQQQQANSSSSAAAQ---------------------------QGFVSKTLDSASAQFAASALMTSEQLLGFKVKDDVVLGLGVNGVLPASGVYKGLHLSSTTPTALVHTSPSTAGSTLLQPSNITQTSGSHSSLSHQVTAASSATTQVLFGNNIRLTVPSSVPTVNSVTPINARHIPRTLSAVPPSALKLAAAANCQVSKVPS-SSSVDSVPRENHESEKPALNNIADNTVAMEVT--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6G2P8-1", "uniprot_id": "A0A8I6G2P8_RAT", "id": "A0A8I6G2P8-1", "name": "Enhancer of polycomb homolog", "aln": "-------------------------------------------------MSKLSFRARALDASKPLPVFRCEDLPDLHEYASINRAVPQMPTGMEKEEESEHHLQRAISAQQVYGEKRDNMVIPVPEAESNIAYYESIYPGEFKMPKQLIHIQPFSLDAEQPDYDLDSEDEVFVNKLKKKMDICPVQFEEMIDRLEKGSGQ------------QPVSLQEAKLLLKEDDELIREVYEYWIKKRKTCRGPSLIPSVKQEKRDGSSTNDPYVAFRRRTEKMQTRKNRKNDEASYEKMLKLRRDLSRAVTILEMIKRREKSKRELLHLTLEIMEKRYNLGDYSGEIMSEVMAQRQPVKPTY-----------------------------------------------------AIPIIPITNS----SQFKHQDVTDAKEFKVNKQDKADLIRPKRKYEKKPKVLPSSAAA-------PQQPSPAALPGFSAKDLNQYDFPSSDEEPLSQVLSGSSEAEEENDPDGPFAFRRKAGCQYYAPHLDQTGNWPWTSPKD-----GGLGDVRYRYCLTTLTVP-QRCLGFARRRVGRGGRVLLDRAHSDYDSMFHHLDLDMLSSPQPSPVNQFANTSETNTSDRPSS-----KDLSQILVDIKSCRWRHFRPRTPSLPDSDSGE----------------------------------------------------LSSRKLHRSISRAGPAQPGAHTCSASTQSRSSSGSTHCAFTAEQY----------QQHQQQLALMQQQQLAQTQQQQ-ANSSSSTAAP---------------------------QGFVSKTLDSASAQFAASALMTSEQLMGFKMKDDVVLGIGVNGVLPASGVYKGLHLSSTTPTALVHTSPSTAGSTLLQPSNITQTSGSHSALSHQVTAANSATTQVLFGNNIRLTVPSSVPTVNSIAPINARHIPRTLSAVPPSALKLAAAANCQVSKVPS-SSSVDSVPRENHESEKPALNNIADNTVAMEVT--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H2F5-1", "uniprot_id": "EPC1_HUMAN", "id": "Q9H2F5-1", "name": "Enhancer of polycomb homolog 1", "aln": "-------------------------------------------------MSKLSFRARALDASKPLPVFRCEDLPDLHEYASINRAVPQMPTGMEKEEESEHHLQRAISAQQVYGEKRDNMVIPVPEAESNIAYYESIYPGEFKMPKQLIHIQPFSLDAEQPDYDLDSEDEVFVNKLKKKMDICPLQFEEMIDRLEKGSGQ------------QPVSLQEAKLLLKEDDELIREVYEYWIKKRKNCRGPSLIPSVKQEKRDGSSTNDPYVAFRRRTEKMQTRKNRKNDEASYEKMLKLRRDLSRAVTILEMIKRREKSKRELLHLTLEIMEKRYNLGDYNGEIMSEVMAQRQPMKPTY-----------------------------------------------------AIPIIPITNS----SQFKHQEAMDVKEFKVNKQDKADLIRPKRKYEKKPKVLPSSAAAT------PQQTSPAALPVFNAKDLNQYDFPSSDEEPLSQVLSGSSEAEEDNDPDGPFAFRRKAGCQYYAPHLDQTGNWPWTSPKD-----GGLGDVRYRYCLTTLTVP-QRCIGFARRRVGRGGRVLLDRAHSDYDSVFHHLDLEMLSSPQHSPVNQFANTSETNTSDKSFS-----KDLSQILVNIKSCRWRHFRPRTPSLHDSDNDE----------------------------------------------------LSCRKLYRSINRTGTAQPGTQTCSTSTQSKSSSGSAHFAFTAEQY----------QQHQQQLALMQKQQLAQIQQQQANSNSSTNTSQNLASNQQKSGFRLNIQGLERTL-----QGFVSKTLDSASAQFAASALVTSEQLMGFKMKDDVVLGIGVNGVLPASGVYKGLHLSSTTPTALVHTSPSTAGSALLQPSNITQTSSSHSALSHQVTAANSATTQVLIGNNIRLTVPSSVATVNSIAPINARHIPRTLSAVPSSALKLAAAANCQVSKVPS-SSSVDSVPRENHESEKPALNNIADNTVAMEVT--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32U369-1", "uniprot_id": "A0AB32U369_DANRE", "id": "A0AB32U369-1", "name": "Enhancer of polycomb homolog", "aln": "-------------------------------------------------MSKLSFRARALDASKPLPVFRCEDLPDLHEYASINRAVPQMPTGMEKEEESEHHLQRAISAQQVYGEKRDNMVIPVPEAESNIAYYESLYPGDFKMPKQLIHIQPFSLDTEQPDYDLDSEDEAFVNKLKKKMDVGALQFEEMIDRLEKGSGQQMLLSKATCIALKPVTLQEAKLLLKEDDELIKEVFEYWSKKRKTCQSGSLIPVVKQEKRDGSSTNDPYVAFRRRTEKMQTRKNRKNDEASYEKMLKLRRDLSRAVTILEMIKRREKSKRELLHLTLEIVEKRNNMSDFGGEVMAEVLAQRALEKP-------------------------------------------------------VIPLIPITNS----TQYRHTEHD--RDYKI-KMDKPEVVRQKRKYEKKPKPLPLAGSV------------HSGPSVFNTKDLNQYDFPSSDDEPFSQMFSGSSEVEEENDPDGVFGFRRRTGCQYHSARSGPVSGWPWSDPAE-----GGVADVRYRYSLTTLTVP-RRCLGLARRRVGRGGRVLLDRAHSEWDTVYHGLDPDSPAFPSLSPTQQQPSTDTSHTSTDTSAPSATPPDLTQILLNIKACRWRHFKPRTAPPDDPDNPEH---------------------------------------------------WSTRRPRRGFLIRPIRTLQTQRGPASIRPPPPPPTP--AFTAEQY----------QQHQEQLVLMQKQQLEQVQQHQQTGSSAVTNNP---------------------------QSLVSKTIDAASAQFAASALVTHEQLLALKSKDE---GVGVNGVVSASGVYKGLHHTSSAVSSILPSVGSTS-TSCPSPTIATTTNNGTSSANHHVGPAGPAPGQALMGGAVRVSVPSPAGTLS------VRQLQRQLT-VPASALKLAANANRPLPKVTTGSTTLDMGPRENHDQEKPPLNSLTENTVAMEVT--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KFP2-1", "uniprot_id": "A0A0B4KFP2_DROME", "id": "A0A0B4KFP2-1", "name": "Enhancer of polycomb-like protein", "aln": "-------------------------------------------------MSKLSFRARHLDPSKQMPIYLAEELPDLPEYSAINRAVPQMPSGMEKEEESEHHLQRAICTGLIIPTP--------EVLQTDQPFYDAYYPPDYKMPRQMIHMQPLGLDTEVPDYDMDSADEDWLSQQQR-LELTELKFEQMMDRLEKSSGQ------------TVVTLNEAKSLLNQDDETSISVYDYWLNKRLKMQHP-LILTVKTESRPGASSNNPYLAFRRRTEKMQTRKNRKNDEASYEKMLKLRRDLQRATTILEMVRRREETKRDHLKMTVNIFEKRVEMRDFNGAVYSELNSQYKNTRPAYNPLYTNQYSQGAAAVGTAGAILAALPTGLLPGGAGAAGNANVFGSASQYLNSSNLTMDAISGSGNGNSSRKEKRPYKKRKHKLPRDKQQHQQQQTQQHQQQQYLPASGGAGVSPAHHLPHHLHHLSRQQSASPAANDSIADSEEEDYFGAGAQNGNKLGSESEEETPFAFRRRSSCVYLPTR-QRDGRYPWDSADEDMAPSGACSDAKYRYTLTSLNYPRPRCIGFARRRLGRGGRILLDRATTNFDDFWSQLDYTVMESVTVNKCRDKIKQRDPDQLCKPSS----PPTVVDLVPAGKPVDGEHPVPELIKEEPSSDTEKPVAATESGRESKERELEEKFENDVDDEFVASDDENVSRLGIYSSAVTLPQSCADLRQKRRRLRRKKQQLRELNAAKRLKRSSEAVATAEDVQLEDEDTKPDLRPLPRAYLQRLALILGQKLKVEEDDNTEVSENVAPELLEMNDPEQLQPPRANHQQHHRSNHNNNNNTVLNNNNSSSSNVMNKDVSISEKINVIKQEAEELVGGKCEDQPVASTSAAAAAARAAEAAAAAEAASSTTTLAAPNPGPSLEEVAKTIKREMIDADDSNEPLSSIRTAAVMLSTQTSVSELMDDEAEDDVNLAQLSSIIRHTAVKKELEAQQHQQQVQH--EQMQAARKMEEDEAAPCLNQLPDVIRLRNIRNSQVHARPKDLFVQAPVDEEFNADYMGGLSPTSSQRLDICNELLSEIRRDWLHFRPKTPTDELSDSQDCEVGKTCDSHAVDWTQDTPISVELNRLGKREAEESDSSSYFLSSGFKYRDLESDAQLLQTVQAQDYARGSSKSPNCSGSGSGSALEFNLSGGDSLNDINNLLGCDDEDDNHEHMLDNILQECAMDDPKALNQATNFWNGILDGEAAVDEVEMADQLLDCIDEKKSKVGAADTSKRAGRNRKARLIQAPVGSSAFTVCPTAETLKERELFFSQAPPVEVPPKEKTPAEVELPEVVVKETANLPVKVEAVEKPQSEVLPVAPQPQQLQPQAITLPTTQLINIPAQISTQKQHQQPQVTQLLNQFANAGPQIIARTEYGGGAAVGDIVTITPHTGSSPLPTLTAQQQLQHQLAQAQLRNVTVQQRQATPQNPNQNQNPQQQLLFQMQRDPSRSLTPLQAAGAGATGNHLIYTTSCGEIVTAGAAASASQKVTYAIQKAGVSSGGATTASIGPNTVITLSNVKVQNDDISSGGSGNSGSSVNIINTASGQQLAVHSIAGMQQQGQQQVQQVTTSTPLLVATPTRNNVQQQQQQLVQQQPIVWRQVSGTNTAVATTAVLSTTVDSSPKAVTNQILWTSRATQKRQLNGPENTDINKLLLNRKLPRKQQIQQQHQQIQLTKQQLQQLVQHEELDDLVATSTGNSGDQMETGDGLQQQQQQQQQQQQLQKLSKVIKMSQFPLLVSDVSLQQQQSVSGQAQQQQLKPNSAAAIAANHNYSLHPASTAIITAQATPQQANKIFLTSSNSGGGGSAGNFTIATASELQAAAAGQKLHYKELPNSNLKLNFVSSAGTGEQTQQVGATTVLLNKSQQQQQQQQHQKLKTLATTGNSQTGQGDKRVLYTSLLNVKPLQKNNSGQMQMQLGPGGLQQVLRGRLNNSAIITRTLPLGTTVNSTGGAVGPTTTTIRQLVTTNANNVSSQDGNLLSAKEVGKALTVEQVIASANNGGVVLPTSNNNNNNNGSGAGGNGGPLNSGVNATGAGGGGSTGAGVGGAGVTSTINRXDADGSGSNSXHRAQPLQVPNGPLLSLASTQTEAETQAVAISMPLADAHVALGQLLQQHHCSCTVCLVNKSELV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P43572-1", "uniprot_id": "EPL1_YEAST", "id": "P43572-1", "name": "Enhancer of polycomb-like protein 1", "aln": "MPTPSNAIEINDGSHKSGRSTRRSGSRSAHDDGLDSFSKGDSGAGASAGSSNSRFRHRKISVKQHLKIYLPNDLKHLDKDELQQREVVEIETGVEKNEEKEVHLHRILQMG--SGHTKHKDYIPTPDASMTWNEYDKFYTGSFQETTSYIKFSATVEDCCGTNYNMDERDETFLN-----------------EQVNKGSSD---------------------ILTEDEFEILCSSFEHAIHERQPFLSMDPESILSFEELKPTLIKSDMADFN-------LRNQLNHEINSHKTHFITQFDPVSQMNTRPLIQLIEKFG---SKIYDYWRERKIEVNGY------EIFPQLKFERPGE-----------------------------------------------------KEEIDPYVCFR----RREVRHPRKTRRIDILNSQRLRALHQELKNAKDLALLVAKRENVSLN--WINDELKIFDQRVKIKNLKRSLNISGEDDDLINHKRKRPTIVTVEQREAELRKAELKRAAAAAAAAKAKNNKRNNQLED--------KSSRLTKQQQQQLLQQQQQQQQNALKTENGKQLANASSSSTSQPITSHVYVKLPSSKIPDIVLEDVDALLNSKEKNARK--FVQEKMEKRKIEDADVFFNLTDDPFNPVFDMSLPKN---------------------------------------------------FSTSNVPFASIASSKFQIDRSFYSSHLPEYLKGISDDIRIYDSNG----------RSRNKDNYNLDTKRIKKTELYDPFQENLEIHSR--------------------------------EYPIKFRKRVGRSNIKYVDRMPNFTTSSTKSACSLMDFVDFDSIEKEQYSREGSNDTDSINVYDSKYDEFVRLYDKWKYDSPQNEYGIKFSDEPARLNQISNDTQVIRFGTMLGTKSYEQLREATIKYRRDYITRLKQKHIQHLQQQQQQQQQQQQQAQQQKQKSQNNNSNSSNSLKKLNDSLINSEAKQNSSITQKNSS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: ** * :. .: : :: ::* .* : :* * :: :*:**:**.* **:* : . *: *. .:: . . *::.. * .:*::*. ** ::. ::::*.*.: * ::: * . ::: ::* :. *. : :. *. *:: ::: *::. : : * . ::: *: :: *:: :: .: *: .* :* : . . : .: . .: : : :. : * ::: : .: : : . . .. . . : . : : : .* :: : : : . : . : . . : . . . : : . . : . .: : : : ::: : : .. : .. . : ::: :. . : * .: : *. : . . . : : . :: : : . : :... *:.: : : ", "identical_positions": 45, "similar_positions": 195, "identity": "2.07%" }, { "cls_id": "homologset.agr.MGI:1278325", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V977-1", "uniprot_id": "G3V977_RAT", "id": "G3V977-1", "name": "Bcl-2-related protein A1", "aln": "MTDCEFMYIHSLAENYLQYVLQVPAFESAPSKTSRVLQRVAFSVQKEVEKNLKPYLDDFHVESIDTARIIFNQVMEKEFEDGIINWGRIVTIFAFGGVLLKKLPQEQIALDVDTYKQVSSFVAEFIMNNTGEWIQQNGGWEDGFTKKFEPKSGWLTFLQMTGKIWEMLFLLKQHY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O55179-1", "uniprot_id": "O55179_MOUSE", "id": "O55179-1", "name": "Bcl-2-related protein A1", "aln": "MSEYEFMYIHSLAEHYLQYVLQVPAFESAPSQACRVLQRVAFSVQKEVEKNLKSYLDDFHVESIDTARIIFNQVMEKEFEDGIINWGRIVTIFAFGGVLLKKLPQEQIALDVGAYKQVSSFVAEFIMNNTGEWIRRNGGWEDGFIKKFEPKSGWLTFLQMTGQIWEMLFLLK---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q16548-1", "uniprot_id": "B2LA1_HUMAN", "id": "Q16548-1", "name": "Bcl-2-related protein A1", "aln": "MTDCEFGYIYRLAQDYLQCVLQIPQPGSGPSKTSRVLQNVAFSVQKEVEKNLKSCLDNVNVVSVDTARTLFNQVMEKEFEDGIINWGRIVTIFAFEGILIKKLLRQQIAPDVDTYKEISYFVAEFIMNNTGEWIRQNGGWENGFVKKFEPKSGWMTFLEVTGKICEMLSLLKQYC", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:: ** **: **:.*** ***:* *.**::.****.**************. **:.:* *:**** :************************* *:*:*** ::*** **.:**::* **************::*****:** *********:***::**:* *** *** ", "identical_positions": 123, "similar_positions": 32, "identity": "70.29%" }, { "cls_id": "homologset.agr.MGI:1278328", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A8L3-1", "uniprot_id": "A0A8I6A8L3_RAT", "id": "A0A8I6A8L3-1", "name": "Aspartyl aminopeptidase", "aln": "--------------------MNPPEAEVAMNGRARKE----------AIQATARELIKFVNRSPSPFHVVAECRSRLLQAGFRELKETEGWD--ILPEN-KYFLTRNSSTIIAFAVGGQYVPGNGFSLIGAHTDSPCLRVKRKS-RRSQVGYHQVGVETYGGGIWSTWFDRDLTLAGRVIIKCPTSGRLEQRFVH-IERPILRIPHLAIHLQRNVNENFGPNTEMHLVPI--LATAVQEELEKGTPE---PGPLS---ATDERHHSVLMSLLCTHLGLS-PDNIMEMELCLADTQPATLGGAYEEFIFAPRLDNLHSCFCALQALIDSCASPASLAREPHVRMVTLYDNEEVGSESAQGAQSLLTELILRRISASPQR---------LTAFEEAIPKSFMISADMAHAVHPNYSDKHEENHRPLFHKGPVIKVNSKQRYASNAVSESLIREVAGQVGVPLQDLMVRNDSPCGTTIGPILASRLGLRVLDLGSPQLAMHSIRETACTTGVLQTLTLFKGFFELFPSVSRNLLVD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z2W0-1", "uniprot_id": "DNPEP_MOUSE", "id": "Q9Z2W0-1", "name": "Aspartyl aminopeptidase", "aln": "---------------------------MAMNGRARKE----------AIQATARELLKFVNRSPSPFHVVAECRSRLLQAGFRELKETEGWD--IVPEN-KYFLTRNSSSIIAFAVGGQYVPGNGFSLIGAHTDSPCLRVKRKS-RRSQVGYHQVGVETYGGGIWSTWFDRDLTLAGRVIIKCPTSGRLEQRLVH-IERPILRIPHLAIHLQRNINENFGPNTEIHLVPI--LATAVQEELEKGTPE---PGPLG---ATDERHHSVLMSLLCTHLGLS-PDSIMEMELCLADTQPAVLGGAYEEFIFAPRLDNLHSCFCALQALIDSCASPASLARDPHVRMVTLYDNEEVGSESAQGAQSLLTELILRRISASPQR---------LTAFEEAIPKSFMISADMAHAVHPNYSDKHEENHRPLFHKGPVIKVNSKQRYASNAVSESMIREVAGQVGVPLQDLMVRNDSPCGTTIGPILASRLGLRVLDLGSPQLAMHSIRETACTTGVLQTLTLFKGFFELFPSVSRNLLVD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9ULA0-1", "uniprot_id": "DNPEP_HUMAN", "id": "Q9ULA0-1", "name": "Aspartyl aminopeptidase", "aln": "---------------MSGHSPTRGAMQVAMNGKARKE----------AVQTAAKELLKFVNRSPSPFHAVAECRNRLLQAGFSELKETEKWN--IKPES-KYFMTRNSSTIIAFAVGGQYVPGNGFSLIGAHTDSPCLRVKRRS-RRSQVGFQQVGVETYGGGIWSTWFDRDLTLAGRVIVKCPTSGRLEQQLVH-VERPILRIPHLAIHLQRNINENFGPNTEMHLVPI--LATAIQEELEKGTPE---PGPLN---AVDERHHSVLMSLLCAHLGLS-PKDIVEMELCLADTQPAVLGGAYDEFIFAPRLDNLHSCFCALQALIDSCAGPGSLATEPHVRMVTLYDNEEVGSESAQGAQSLLTELVLRRISASCQH---------PTAFEEAIPKSFMISADMAHAVHPNYLDKHEENHRPLFHKGPVIKVNSKQRYASNAVSEALIREVANKVKVPLQDLMVRNDTPCGTTIGPILASRLGLRVLDLGSPQLAMHSIREMACTTGVLQTLTLFKGFFELFPSLSHNLLVD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QRP8-1", "uniprot_id": "F1QRP8_DANRE", "id": "F1QRP8-1", "name": "Aspartyl aminopeptidase", "aln": "--------------------------MQSFIMKSSKE----------AVQAAAKEFLNFVNKGVSPYHVVEECKSRLLKAGFTELKEAEHWD--IKPAS-KYFVTRNYSTIIAFAVGGLYKPGNGFSMIGAHTDSPCLRVKPRS-KKTKLGFLQVGVECYGGGIWNTWFDRDLTIAGRVMVKS--EGKLVQRLVH-VPRPILRIPHLAIHLQRDINDSFGPNKENHLAPL--LATAVQEELETGSAS---SGDASNATCVAEKHQPALIQMLCGLLSVE-SNDLLDFELCLVDTQPGALGGAYEEFIFSPRLDNLHSCFCALTALVDSST-PDSLAKDPNVRMVTLYDNEEVGSESAQGAHSNLTELILQRLASSRDN---------LTAFQEAVPLSYMISADMAHAAHPNYQEKHEENHRPAFHKGPVIKFNSNQRYATTAVTAAVLREIAGKVGVPLQDVMVRNDSPCGTTIGPILAARLGMAVLDLGAPQLAMHSIREMCCTSGVLQTTTLFKGFFENFPFVRSTVTVD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P38821-1", "uniprot_id": "DNPEP_YEAST", "id": "P38821-1", "name": "Aspartyl aminopeptidase 4", "aln": "------------------------MFRIQLRTMSSKT----------CKSDYPKEFVSFLNSSHSPYHTVHNIKKHLVSNGFKELSERDSWAGHVAQKG-KYFVTRNGSSIIAFAVGGKWEPGNPIAITGAHTDSPALRIKPIS-KRVSEKYLQVGVETYGGAIWHSWFDKDLGVAGRVFVKDAKTGKSIARLVD-LNRPLLKIPTLAIHLDRDVNQKFEFNRETQLLPIGGLQEDKTEAKTEKEIN---NGEFTSIKTIVQRHHAELLGLIAKELAIDTIEDIEDFELILYDHNASTLGGFNDEFVFSGRLDNLTSCFTSMHGLT--LAADTEIDRESGIRLMACFDHEEIGSSSAQGADSNFLPNILERLSILKGDGSDQTKPLFHSAILETSAKSFFLSSDVAHAVHPNYANKYESQHKPLLGGGPVIKINANQRYMTNSPGLVLVKRLAEAAKVPLQLFVVANDSPCGSTIGPILASKTGIRTLDLGNPVLSMHSIRETGGSADLEFQIKLFKEFFERYTSIESEIVV-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P14904-1", "uniprot_id": "AMPL_YEAST", "id": "P14904-1", "name": "Vacuolar aminopeptidase 1", "aln": "MEEQREILEQLKKTLQMLTVEPSKNNQIANEEKEKKENENSWCILEHNYEDIAQEFIDFIYKNPTTYHVVSFFAELLDKHNFKYLSEKSNWQDSIGEDGGKFYTIRNGTNLSAFILGKNWRAEKGVGVIGSHVDALTVKLKPVSFKDTAEGYGRIAVAPYGGTLNELWLDRDLGIGGRLLYKKKGTNEIKSALVDSTPLPVCRIPSLAPHFGKPAEGPFD--KEDQTIPVIGFPTPDEEGNEPPTDDEKKSP-------LFGKHCIHLLRYVAKLAGVE-VSELIQMDLDLFDVQKGTIGGIGKHFLFAPRLDDRLCSFAAMIALICYAKDVNTEESD-LFSTVTLYDNEEIGSLTRQGAKGGLLESVVERSSSAFTKK--------PVDLHTVWANSIILSADVNHLYNPNFPEVYLKNHFPVPNVGITLSLDPNGHMATDVVGTALVEELARRNGDKVQYFQIKNNSRSGGTIGPSLASQTGARTIDLGIAQLSMHSIRAATGSKDVGLGVKFFNGFFKHWRSVYDEFGEL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . .:*::.*: . :.:*.* . * . .* *.* . * : . *:: ** :.: ** :* : . : ..: *:*.*: :::* * : : ::.* *** : *:*:** :.**:: * .. :*. *: :** ** *: : : * * : *: : * . :* *: :. .:. ..: :::* * * : ..:** ..*:*: ***: ..* :: .* : . :: :*:**:** : ***.. : ::.* : : . . * ::*:*: * :**: : : .:* * * .:..:.: : : ::..:* :* . : *:: .* **** **:: * .:*** . *:***** : .: .:*: **: : : . ", "identical_positions": 98, "similar_positions": 153, "identity": "18.39%" }, { "cls_id": "homologset.agr.MGI:1278330", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ET64-1", "uniprot_id": "NSMA_RAT", "id": "Q9ET64-1", "name": "Sphingomyelin phosphodiesterase 2", "aln": "------------------------------MKHNFSLRLRVFNLNCWDIPYLSKHRADRMKRLGDFLN---------------------LESFDLALLEEVWSEQDFQYLKQKLSLTYPDAHYFRSGIIG-SGLCVFSRHPIQEIVQHVYTLNGYPYKFYHGDWFCGKAVGLLVLHLSGLVLNAYVTHLHAEYSRQ-KDIYFAHRVAQAWELAQFIHHTSKKANVVLLCGDLNMHPKDLGCCLLKEWTGLRDAFVETEDFKGSEDGCTMVPKNCYVS-----------QQDLGPFPFGVRIDYVLYKAVSGFHICCKTLKT-TTGCDPHNGTPFSDHEALMATLCVKHSPPQEDPCSAHGS----AERSALISALREARTELGRG----------IAQARWWAALFGYVMILGLSLLVLLCVLAAG-----EEAR----EVAIMLWTPSVGLVLGAG-----AVYLFHKQEAKSLCRAQAEIQHVLTRTTETQDLGSEPHPTHCR-QQEADRAEEK-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70572-1", "uniprot_id": "NSMA_MOUSE", "id": "O70572-1", "name": "Sphingomyelin phosphodiesterase 2", "aln": "------------------------------MKLNFSLRLRVFNLNCWDIPYLSKHRADRMKRLGDFLN---------------------LENFDLALLEEVWSEQDFQYLRQRLSLTYPDAHYFRSGMIG-SGLCVFSKHPIQEIFQHVYSLNGYPYMFHHGDWFCGKSVGLLVLRLSGLVLNAYVTHLHAEYSRQ-KDIYFAHRVAQAWELAQFIHHTSKNADVVLLCGDLNMHPKDLGCCLLKEWTGLHDAFVETEDFKGSDDGCTMVPKNCYVS-----------QQDLGPFPSGIRIDYVLYKAVSEFHVCCETLKT-TTGCDPHSDKPFSDHEALMATLYVKHSPPQEDPCTACGP----LERSDLISVLREARTELGLG----------IAKARWWAAFSGYVIVWGLSLLVLLCVLAAG-----EEAR----EVAIILCIPSVGLVLVAG-----AVYLFHKQEAKGLCRAQAEMLHVLTRETETQDRGSEPHLAYCL-QQEGDRA--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60906-1", "uniprot_id": "NSMA_HUMAN", "id": "O60906-1", "name": "Sphingomyelin phosphodiesterase 2", "aln": "------------------------------MKPNFSLRLRIFNLNCWGIPYLSKHRADRMRRLGDFLN---------------------QESFDLALLEEVWSEQDFQYLRQKLSPTYPAAHHFRSGIIG-SGLCVFSKHPIQELTQHIYTLNGYPYMIHHGDWFSGKAVGLLVLHLSGMVLNAYVTHLHAEYNRQ-KDIYLAHRVAQAWELAQFIHHTSKKADVVLLCGDLNMHPEDLGCCLLKEWTGLHDAYLETRDFKGSEEGNTMVPKNCYVS-----------QQELKPFPFGVRIDYVLYKAVSGFYISCKSFET-TTGFDPHRGTPLSDHEALMATLFVRHSPPQQNPSSTHGP----AERSPLMCVLKEAWTELGLG----------MAQARWWATFASYVIGLGLLLLALLCVLAAG-----GGAG----EAAILLWTPSVGLVLWAG-----AFYLFHVQEVNGLYRAQAELQHVLGRAREAQDLGPEPQPALLLGQQEGDRTKEQ-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QUD7-1", "uniprot_id": "F1QUD7_DANRE", "id": "F1QUD7-1", "name": "Sphingomyelin phosphodiesterase 2", "aln": "------------------------------MAPQQPGNLRVFSLNCWGIRFLSKLCAQRYEMIGELLG---------------------REQHDIALLQEVWSERDFLFLKRKLSCSHPYTHYFKSGVIG-SGLAVFSKHRIQDALLYQYSLNGYPYMLSHGDWFGGKAAGLVIVEVFGLKAHVYVTHLHAEYSRA-QDGYLPHRIVQSWELQQFVRHTSHGADLVILGGDLNMHPQDLGNRLLRSHTGLRDCYTETDKFDGCEDGHTLIANNHFTK-----------KQDLIPFEKGIRIDYILIKGSQRVSVKCESLST-TKGSVSDKPFPYSDHEALMADLNLLSSQD----CTDAPP------ASDQMDVVSEARAVVKEG----------LGKTEALRDRSLHLMFAG--LLLLLLVLCSSSFFSFSAAG--------FLGAVCVFILLSGA-----LLYMLFTTHIKVLKETEDQMMLRSQNLQTKLTGCRVSGSSSSFHASPEIQPSSPFKREE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E7FBR1-1", "uniprot_id": "E7FBR1_DANRE", "id": "E7FBR1-1", "name": "sphingomyelin phosphodiesterase", "aln": "------------------------------MTTSEPIKFRVLSLNCWGIQYLSKKRQERFVLIGELLN---------------------QEELDVALLQEVWCEKDFLYLKKKLSTVYPHSHYFKSGFFG-SGLAVFSRHQIHDAFLYRYSLNGYPYMAQHGDWFGGKAVGKVLLNISGLKVHVFVTHLHAEYCRE-KDSYLSHRVVQAWELQQFIRHTSAGADVVILGGDLNMHPDDLGTRLLRNYTGLQDSFTEAATFDGCEGGLTHISENPFTL-----------ADGLAPFGGGIRIDYIMFKGSGEVDVSCESLST-TKGPVPGQPFPYSDHEALTAQFLFTPTKKG-NKCAENKSGCVLDDLPELVNTVNEARTEVKVG----------LHCSEGMRYTAARTGIMGLVLLILELVIAAIPLFALGAEQPFPKATFYLLGALCFAILLSTL-----MLYIFYSMEVKALQGTEDQMRLAVSSLQEQLKEYPKVLFSDRQQNPLDCKNLAHL----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VZS6-1", "uniprot_id": "NSMA_DROME", "id": "Q9VZS6-1", "name": "Putative neutral sphingomyelinase", "aln": "---------------------------------MLLLELNILTLNIWGIPYVSSDRRPRIDAICKELA---------------------SGKYDIVSLQEVWAQEDSELLQKGTEAVLPHSHYFHSGVMG-AGLLVLSKYPILGTLFHAWSVNGYFHRIQHADWFGGKGVGLCRILVGGQMVHLYNAHLHAEYDNA-NDEYKTHRVIQAFDTAQFIEATRGNSALQILAGDLNAQPQDISYKVLLYTSKMLDS-CDSDSFR-----TNECEHNSYTS-----------KQARERNPLGIRIDHIFVRGGDHVNAEIAEYKLPFPERVPGEKFSFSDHEAVMAKLKLFKLEPRSEEPVATIEVNCLVEDGETCSVREVGAGDALTGEDDQSSQHQPEIQCNGSSTSIQSMPAARTAALLEALALCDASLLQLNTDRILYYSAATFLFVLLVLLVEFTAPVGMRTIFLLLKFIVFGVILFCVFMASIWNYMERNGVLQGKKSMEVMLHHAQKYEYFY------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40015-1", "uniprot_id": "ISC1_YEAST", "id": "P40015-1", "name": "Inositol phosphosphingolipids phospholipase C", "aln": "MYNRKDRDVHERKEDGQSEFEALNGTNAIMSDNSKAYSIKFLTFNTWGLKYVSKHRKERLRAIADKLAGHSMLTPISDELLPNGGDSNENEDYDVIALQEIWCVEDWKYLASACASKYPYQRLFHSGILTGPGLAILSKVPIESTFLYRFPINGRPSAVFRGDWYVGKSIAITVLNTGTRPIAIMNSHMHAPYAKQGDAAYLCHRSCQAWDFSRLIKLYRQAGYAVIVVGDLNSRPGSLPHKFLTQEAGLVDSWEQLHGKQDLAVIARLSPLQQLLKGCTTCDSLLNTWRAQRQPDEACRLDYALIDPDFLQTVDAGVRFT---ERIPHLDCSVSDHFAYSCTLNIVPQGTESRPSTSVKR---AKTHDRELILQRYSNYETMIE-----------CIHTYLKTAQRQKFFRGLHFWASILLLIAS----------------LVVTTFTANKAGWSS-----IFWVLFAIAVSISGTIDGAISFLFGRSEIRALIEVEQEVLDAEHHLQTFLSEK------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :..:.:* *.: ::*. * : . * . *: *:*:*. .* * * : *:**.: .** ::*: * : :.:** :.**: **. . : :*:** * . . * ** *::: :::. . :: **** :* .: .* : : *. : : . *:*: : . . *** * . : . . : .: .::: : ", "identical_positions": 46, "similar_positions": 78, "identity": "8.83%" }, { "cls_id": "homologset.agr.MGI:1278332", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8N143-1", "uniprot_id": "BCL6B_HUMAN", "id": "Q8N143-1", "name": "B-cell CLL/lymphoma 6 member B protein", "aln": "----MGSPAAPEG---ALGYVREFTRHSSDVLGNLNELRLRGILTDVTLLVGGQPLRAHKAVLIACSGFFYSIFRGRAG--VGVD--VLSLPGGPEARGFAPLLDFMYTSRLRLSPATAPAVLAAATYLQMEHVVQACHRFIQASY--------------EPLG-----------------------------------ISLRPLEAEPPTPPTAP--------PPGSPRRSEGHPDPPTESRSCSQG------PPSPASPDPKACNWKKYKYIVLNSQASQAGSLVGERSSGQPCPQARLPSGDEASSSSSSSSSSSEEGPIPGPQSR--LSPTAATVQFKCGAPASTPYLLTSQAQDTSGSPSERARPLPGSEFFSCQNCEAVAGCSSGLDSLVPGDEDKPYKCQLCRSSFRYKGNLASHR-TVHTGEKPYHCSICGARFNRPANLKTHSRIHSGEKPYKCETCGSRFVQVAHLRAHVLIHTGEKPYPCPTCGTRFRHLQTLKSHVRIHTGEKPYHCDPCGLHFRHKSQLRLHLRQKHGAATNTKVHYHILGGP-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O88282-1", "uniprot_id": "BCL6B_MOUSE", "id": "O88282-1", "name": "B-cell CLL/lymphoma 6 member B protein", "aln": "----MGSTAAPEG---ALGYVREFTRHSSDVLSNLNELRLRGILTDVTLLVGGQPLRAHKAVLIACSGFFYSIFRGRAG--LGVD--VLSLPGGPEARGFAPLLDFMYTSRLRLSPATAPAVLAAATYLQMEHVVQACHRFIQASY--------------EPLG-----------------------------------ISLRPVEVEPPRPPTVA--------PPGSPRRSEGHPDPPTESRSCSQG------SPSPASPDPKACNWKKYKFIVLNSQTSQAGSLVGE-SSGQPCPQARLPSGDEACSSSSSS----EEGTTPGLQSR--LSLATTTARFKCGALANNSYLFTPRAQETSLPASKQANPPPGSEFFSCQNCEAVAGCSSGLELLAPGDEDKPYKCQLCRSAFRYKGNLASHR-TVHTGEKPYRCSICGARFNRPANLKTHSRIHSGEKPYKCETCGSRFVQVAHLRAHVLIHTGEKPYPCPTCGTRFRHLQTLKSHVRIHTGEKPYHCDPCGLHFRHKSQLRLHLRQKHGAATNTKVRYHILGGP-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M1PRU8-1", "uniprot_id": "A0A8M1PRU8_DANRE", "id": "A0A8M1PRU8-1", "name": "", "aln": "MEEEHRSPFAAAHVMEMKGYVKEFTRHSNDVLLNLNELRHRDILTDATLLVGTTKLRAHCAVLIACSGFFYTLFSRRVAGICGEQGFSLTLPEGLDAGSVSLLLDFMYTSCLPLTPRTVPGVLTAATYLQMEHVADTCRAFIQHSEGISASPSLMEPVFRTALGGRSPPAHPTVFSPSRPTAEAEDPIPDRARIPDESFASLDPGTCQTPIPKTQTKLEDSSPCTPDSPSQSSGQPNSPAESSGCSLSPQLKKRSESKLTPDPKACNWKKYKYIVLNPLCATPIKEEGPEEDRHSQNHAPFTSDRMEAASKTTN--NIWNGEEAGLNDRKILSLPYNTSQQKISFAPRHVVEHTLQPLSLSISGDQ--------GLCSPYVCSQIANQGHLLG-------QHPIKFENLSTQLSYIGNQGTHTKPSSSGDKPYRCNICGAQFNRPANLKTHSRIHSGEKPYRCDTCGARFVQVAHLRAHVLIHTGEKPYPCNTCGTRFRHLQTLKSHLRIHTGEKPYSCEKCHLHFRHKSQLRLHLRQKHGAITNTKIRYKVLADPYQPAPALLQAC", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0ABK0M744-1", "uniprot_id": "A0ABK0M744_RAT", "id": "A0ABK0M744-1", "name": "Monocarboxylate transporter 13", "aln": "---MVHRTEPPDG---GWGWMVVLSAFFQSALVFG---VLRSFGVFFVEFVAAFEEQAARVSWIASIGIAVQQFGSPIG------------------------------SALSTKLGPRPVVMTGGILAALGMLLASFATSLTHLY--------------LSIG------------------------------------LLSGSGWALTFTPTLA-----------------CLSRYFSQRRSLAMG-------LALTGVGISSFAFAPLFQWLLNNYAWRGALLLVSALSLHLVACGALLRPLSLTEDTAVG------GPWAQITSL---LCHGPFLRYTVALTLINTGYFIPYVHLVAHLQDLGWDPLPAAFLLSVAAISDLVG----------------------RVASGWLGDAVPGP---VARLLMLWTTLTGVSLALFPVAQASTTLVVLAVAYGFTSG--ALTPVAFSVIPELVGTGR-----IYCG--LGLVQMIESVGGLLG--APLSGKENRVADWAGHVMVSSWGKEPGWCMLIVPSSM----------------", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .. *:: :: . ...* *.: . . :*. :* . **. *: * . * * . . * *::.. : : : : .:* * . . * . . :: . : . : . .: : :** . : . : ..: . * . . : . . : . : * . :.. : *: . : .: *. : . :: : : .* : :. **. *: **. ** : :* ::* : * . : : :: * ", "identical_positions": 34, "similar_positions": 99, "identity": "6.0%" }, { "cls_id": "homologset.agr.MGI:1278334", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B5DF11-1", "uniprot_id": "ZFAN5_RAT", "id": "B5DF11-1", "name": "AN1-type zinc finger protein 5", "aln": "MAQETNQTPGPMLCSTGCGFYGNPRTNGMCSVCYKEHLQRQQNSGRMSPMGTASGSNSPTSDSASVQRADATLNNCEGAAGSTSEKSRN-VPVAALPVTQQMTEMSISREDKITSPKTEVSEPVVTQPSPSVSQPSSSQS--EEKAPELPKPKKNRCFMCRKKVGLTG-FDCRCGNLFCGLHRYSDKHNCPYDYKAEAAAKIRKENPVVVAEKIQRI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88878-1", "uniprot_id": "ZFAN5_MOUSE", "id": "O88878-1", "name": "AN1-type zinc finger protein 5", "aln": "MAQETNQTPGPMLCSTGCGFYGNPRTNGMCSVCYKEHLQRQQNSGRMSPMGTASGSNSPTSDSASVQRADAGLNNCEGAAGSTSEKSRN-VPVAALPVTQQMTEMSISREDKITTPKTEVSEPVVTQPSPSVSQPSSSQS--EEKAPELPKPKKNRCFMCRKKVGLTG-FDCRCGNLFCGLHRYSDKHNCPYDYKAEAAAKIRKENPVVVAEKIQRI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O76080-1", "uniprot_id": "ZFAN5_HUMAN", "id": "O76080-1", "name": "AN1-type zinc finger protein 5", "aln": "MAQETNQTPGPMLCSTGCGFYGNPRTNGMCSVCYKEHLQRQQNSGRMSPMGTASGSNSPTSDSASVQRADTSLNNCEGAAGSTSEKSRN-VPVAALPVTQQMTEMSISREDKITTPKTEVSEPVVTQPSPSVSQPSTSQS--EEKAPELPKPKKNRCFMCRKKVGLTG-FDCRCGNLFCGLHRYSDKHNCPYDYKAEAAAKIRKENPVVVAEKIQRI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BJ38-1", "uniprot_id": "A0A8M2BJ38_DANRE", "id": "A0A8M2BJ38-1", "name": "", "aln": "MAQETNQSPVPILCTTGCGFYGNPRTNGMCSVCYKEHLNRQQSSDR-SPMSPLAAG-SPSAEASAIQRLEASINKAETLPAPSTETMRESIPSSSLPVTQKMTEMSISREEKALSPKAETVEPVITQPTSSYSPIPVAQANDDAKSPDSSKPKKNRCFTCRKRVGLTG-FDCRCGNLFCGIHRYSDKHNCTYDYKAEAAAKIRKENPVVVADKIQRI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VHF4-1", "uniprot_id": "Q9VHF4_DROME", "id": "Q9VHF4-1", "name": "", "aln": "MERESN--PMQPMCRSGCGFYGNPATDGLCSVCYKDSLRKKQ----QPPVSSTPVS-VPSPQPSPTFSPAIAITNTAQPTVTSLQQPHN-------DVKEKITEEAAAAAKVNSEAITSATGPNTSTQAAASANEEDDKDKEDDKD---AKKKKNRCGECRKKVGLTG-FQCRCGGLYCAVHRYSDKHNCTFDYREHGAQEIRRNNPVVVGEKIQKI", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W371-1", "uniprot_id": "Q9W371_DROME", "id": "Q9W371-1", "name": "AN1-type domain-containing protein", "aln": "----------------------------------------------MRSASVPNIIIWSGMDAGTQSAMSIQLHGFSHHLEQRDQEERD---------QGDAQEQQQPQQQQDQPPMEEQDSRAVNSKDGAANQDTSADSGQDQDGNQAQDSTKKRCDKCGKKLGITGGFPCRCGGTYCAVHRYSDRHECNFDYRQMGAIQIRRDNPVVVASKLRKL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . :... : : :: . * . . . . . : . : . . .*:** * *::*:** * ****. :*.:*****:*:* :**: .* :**::*****..*::::", "identical_positions": 33, "similar_positions": 45, "identity": "15.21%" }, { "cls_id": "homologset.agr.MGI:1278335", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B6RHI6-1", "uniprot_id": "B6RHI6_RAT", "id": "B6RHI6-1", "name": "E3 ubiquitin-protein ligase LNX", "aln": "MNQPD------------LADDPDPSPEPLCVVCGQNHSPEENHFYTYTEDVDDDLVCHICLQALLDPLDTPCGHTYCTLCLTNFLVEKDFCPVDRKPVVLQHCKKSNILVNKLLNKLLVNCPFTEHCSEVLQRCNLQYHFQTSCKGASHYGLTKDRKRRSQDG-CPDGCASLTATTLSPEVSAAATISLMTDEPGLDNPAYTSSVEDGE---PVTNPSDTGRSNRTRARPFERSTMRSRSFKKINRALSALRRTKSGSAVANHADQGRDNSENDTVPEV-----FPRLFHLIPDGEITSIKINRVDPNESLSIRLVGGSETPLVHIIIQHIYRDGVIARDGRLLPGDIILKVNGMDISNVPHNYAVRLLRQPCQVLRLTVLREQKFRSRSNAPAPDSYGP------RDDSFHVILNKSSPEEQLGIKLVRRVDEPGVFIFNVLNGGVADRHGQLEENDRVLAINGHDLRFGSPESAAHLIQASERRVHLVVSRQVRQPSPDIFQEAGCISNGQQSPVSGERSTSSK---PAATCHEKVVSVQKDPNESLGMTVGGGASHREWDLPIYVISVEPGGVISRDGRIKTGDILLNVNGIELTEVSRTEAVAILKSTPSSVVLKALEVKE-QETQEDCS-----PAALDSN----HNVTPPGD-WSPSWVMWLELPQYLYNCKDVILRRNTAGSLGFCIVGGYEEYSGNQPFFIKSIVEGTPAYNDGRIRCGDILLAVNGRSTSGMMHACLARMLKELKGKITLTIASWPGTFL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70263-1", "uniprot_id": "LNX1_MOUSE", "id": "O70263-1", "name": "E3 ubiquitin-protein ligase LNX", "aln": "MNQPD------------LADDPDPSPEPLCIVCGQNHSPEENHFYTYTEDVDDDLICHICLQALLDPLDTPCGHTYCTLCLTNFLVEKDFCPVDRKPVVLQHCKKSSILVNKLLNKLLVTCPFTEHCTEVLQRCDLQHHFQTSCKGASHYGLTKDRKRRSQDG-CPDGCASLMATTLSPEVSAAATISLMTDEPGLDNPAYVSSVEDGE---PVANSSDSGRSNRTRARPFERSTMRSRSFKKINRALSALRRTKSGSVVANHVDQGRDNSENTTVPEV-----FPRLFHLIPDGEITSIKINRADPSESLSIRLVGGSETPLVHIIIQHIYRDGVIARDGRLLPGDIILKVNGMDISNVPHNYAVRLLRQPCQVLRLTVLREQKFRSRSNAHVPDSYGP------RDDSFHVILNKSSPEEQLGIKLVRRVDEPGVFIFNVLNGGVADRHGQLEENDRVLAINGHDLRFGSPESAAHLIQASERRVHLVVSRQVRQSSPDIFQEAGWISNGQQSPGPGERNTASK---PAATCHEKVVSVWKDPSESLGMTVGGGASHREWDLPIYVISVEPGGVISRDGRIKTGDILLNVNGIELTEVSRTEAVAILKSAPSSVVLKALEVKE-QEAQEDCS-----PAALDSN----HNVTPPGD-WSPSWVMWLELPQYLCNCKDVILRRNTAGSLGFCIVGGYEEYSGNKPFFIKSIVEGTPAYNDGRIRCGDILLAVNGRSTSGMIHACLARMLKELKGRITLTIASWPGTFL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TBB1-1", "uniprot_id": "LNX1_HUMAN", "id": "Q8TBB1-1", "name": "E3 ubiquitin-protein ligase LNX", "aln": "MNQPE------------SANDP----EPLCAVCGQAHSLEENHFYSYPEEVDDDLICHICLQALLDPLDTPCGHTYCTLCLTNFLVEKDFCPMDRKPLVLQHCKKSSILVNKLLNKLLVTCPFREHCTQVLQRCDLEHHFQTSCKGASHYGLTKDRKRRSQDG-CPDGCASLTATAPSPEVSAAATISLMTDEPGLDNPAYVSSAEDGQ---PAISPVDSGRSNRTRARPFERSTIRSRSFKKINRALSVLRRTKSGSAVANHADQGRENSENTTAPEV-----FPRLYHLIPDGEITSIKINRVDPSESLSIRLVGGSETPLVHIIIQHIYRDGVIARDGRLLPGDIILKVNGMDISNVPHNYAVRLLRQPCQVLWLTVMREQKFRSRNNGQAPDAYRP------RDDSFHVILNKSSPEEQLGIKLVRKVDEPGVFIFNVLDGGVAYRHGQLEENDRVLAINGHDLRYGSPESAAHLIQASERRVHLVVSRQVRQRSPDIFQEAGWNSNGSWSPGPGERSNTPKPLHPTITCHEKVVNIQKDPGESLGMTVAGGASHREWDLPIYVISVEPGGVISRDGRIKTGDILLNVDGVELTEVSRSEAVALLKRTSSSIVLKALEVKE-YEPQEDCSS----PAALDSN----HNMAPPSD-WSPSWVMWLELPRCLYNCKDIVLRRNTAGSLGFCIVGGYEEYNGNKPFFIKSIVEGTPAYNDGRIRCGDILLAVNGRSTSGMIHACLARLLKELKGRITLTIVSWPGTFL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B7L4-1", "uniprot_id": "A0A8M2B7L4_DANRE", "id": "A0A8M2B7L4-1", "name": "", "aln": "MSDQEEAGAVAMPVCGATGVTPTAPPPDLCHICGQRHLQEENHEYTYKEDVDDDLMCHICLQPLIRPLDTPCGHTYCQECLTNFLLESDFCPVDRTPLMLQKCRKSSLLVHKLLDKLMVSCPFADHCTEVMPRGEMEGHIRCRCKGASHYGLSAERKRRSQEGDCTDSTSELTLAALPGEGCPSSAIALLSDEPGLVNPAYEPSVEDNSQSGSTTSLAARSGSRKSEYRNFDRTSVRSRSFRRLNRAFSVLRRTKSGTAVANDTTEERDNLRNANIPAEGELFALPQLHHLIPDGEVTSIKITRADPCEPLAISIVGGNETPLVRILIQDIYREGVIARDGRLLPGDMILKVNGIDISNVPHCYAVAALKQPCTLLRLTVLREQRHRYRSHHHSPTEAFPAHTATIRDDSLHVVLVKRAPDEQLGIKLVRRPDEHGVFIFHLLEGGLAARDGRLRVDDRVLAINGHDLRYGAPEHAALLIQASEDRVHFIVSRQTHIPAPDILQEAPWNMEGPPPYSPVDIEHTLLDSCQKPACYEKTVTLLKEPHDSLGMTVAGGMSSRGWDLPVYVTNVDPNGVVGQEGSIRKGDILLNVNGVDLTGVTRSEAVANLKNTSSPVVLQVLEMRPPNESSLDCMPPLHSPCALSPSSPGDVKLPPPNDDYAPLWVSWLQLPRHLYCCKDIVLRRSTSGSLGFSIVGGQEELNCNQSFFIRSIVEGTPAYNDGRIRCGDILLEVNGKSTWGMTHTALVRLLKELRGRITLTIVSWPGSLL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.: : . * ** :*** * **** *:* *:*****:******.*: *********** ******:*.****:**.*::**:*:**.:**:***:**:*.*** :**::*: * ::: *:: *********: :******:* *.*. :.* :: . * ..:::*:*::***** **** .*.**.. .. . . *.::. * *:*:::*****:::***:*.*******:.***.. : *:* .* . * :*:*.*******:*****.*.** *.*:* :***.*****:*:**.***:*************:******:******* *** *:*** :* ***:***:.* *.: * * ****:**:* * :*:*********: ** *****::*:**:* *.*:*. :************:*:** ** ****** ***::****.: :***:*** :* . . : . : :*:**.*.: *:* :******.** * * ****:** .*:*.**:.::* *:.*******:*::** *:*:**** ** :.*.:**:.**:: *.. ** *.**... ::.**.* ::* ** **:**: * ***::***.*:*****.**** ** . *:.***:********************* ***:** ** *:.*.*:****:*:*****.****::*", "identical_positions": 417, "similar_positions": 194, "identity": "54.23%" }, { "cls_id": "homologset.agr.MGI:1278336", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O76039-2", "uniprot_id": "CDKL5_HUMAN", "id": "O76039-2", "name": "Cyclin-dependent kinase-like 5", "aln": "-MKIPNIG----NVMNKFEILG-----------------------VVGEGAYG----VVLKCRHKETHEIVAIKKFKDSEENEEVKETTLRELKMLRTLKQENIVELKEAFRRRGKLY---LVFEYVEKNMLELLEEMPNG---VPPEKVKSYIYQLIKAIHWCHKNDIVHRDIKPENLLISHN-DVLKLCDFGFARNLSEGNNANYTEYVATRWYRSPELLLGAP-YGKSVDMWSVGCILGELSDGQPLFPGESEIDQLFTIQKVLGPLPSEQMKLFYSNPRFHGLRFPAVNHPQSLERRYLGILNSVLLDLMKNLLKLDPADRYLTEQCLNHPTFQTQRLLDRSPSRSAKRKPYHVESSTLSNRNQAGKSTALQSHHRSNSKDIQNLSVGLPRADEGLPANESFLNGNLAGASLSPLHTKTYQASSQPGSTSKDLTNNNIPHLLSPKEAKSKTEFDFNIDPKPSEGPGTKYLKSNSRSQQNRHSFMESSQSKAGTLQPNEKQSRHSYIDTIPQSSRSPSYRTKAKSHGALSDSKSVSNLSEARAQIAEPSTSRYFPSSCLDLNSPTSPTPTRHSDTRTLLSPSGRNNRNEGTLDSRRTTTRHSKTMEELKLPEHMDSSHSHSLSAPHESFSYGLGYTSPFSSQQRPHRHSMYVTRDKVRAKGLDGSLSIGQGMAARANSLQLLSPQPGEQLPPEMTVARSSVKETSREGTSSFHTRQKSEGGVYHDPHSDDGTAPKENRHLYNDPVPRRVGSFYRVPSPRPDNSFHENNVSTRVSSLPSESSSGTNHSKRQPAFDPWKSPENISHSEQLKEKEKQGFFRSMKKKKKKSQTVPNSDSPDLLTLQKSIHSASTPSSRPKEWRPEKISDLQTQSQPLKSLRKLLHLSSASNHPASSDPRFQPLTAQQTKNSFSEIRIHPLSQASGGSSNIRQEPAPKGRPALQLPGQMDPGWHVSSVTRSATEGPSYSEQLGAKSGPNGHPYNRTNRSRMPNLNDLKETAL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0LCR6-1", "uniprot_id": "A0ABK0LCR6_RAT", "id": "A0ABK0LCR6-1", "name": "Cyclin-dependent kinase-like 5", "aln": "-MKIPNIG----NVMNKFEILG-----------------------VVGEGAYG----VVLKCRHKETHEIVAIKKFKDSEENEEVKETTLRELKMLRTLKQENIVELKEAFRRRGKLY---LVFEYVEKNMLELLEEMPNG---VPPEKVKSYIYQLIKAIHWCHKNDIVHRDIKPENLLISHN-DVLKLCDFGFARNLSEGNNANYTEYVATRWYRSPELLLGAP-YGKSVDMWSVGCILGELSDGQPLFPGESEIDQLFTIQKVLGPLPSEQMKLFYSNPRFHGLRFPAVNHPQSLERRYLGILNSVLLDLMKNLLKLDPADRYLTEQCLNHPTFQTQRLLDRSPSRSTKRKPYHVESSTLSNRSQSTKGGALQTHHRSNSKDIQNLSVGLPRAEEGLPANESFLNGNLAGATLSPMHTKTYQASTQPGSSSKDLTNNNIPHLLSPKEAKSKTEFDFNIDPKPSEGPGTKYLKSSTRSQQNRHSFMESSQSKAGTLQPSEKQSRHSYIDTIPQSSRSPSYRTKAKSHGALSDSKSVSNLSEARAQITETNTSRYFPSSCLDLNSPTSPTPTRHTDTRTLLSPSGRNNRNEGTLDSRRTTTRHSKTMEELKLPEHMDSSHSHSLSAPHESFSYGLGYTSPFSSQQRPHRHSMYVTRDKVRAKGIDGSLSIGQGMAARANSLQLLSPQPGEQLPPEMTVARPSVKESSREGTSSFHTRQKSEGGVYHDPHSDDGTAPKENRHLYNDPVPRRVGSFYRVPSPRPDNSFHENNVSTRVSSLPSDSSSGTNHSKRQPGFDPWKSPENISHSDQLKEKEKQGFFRSMKKKKKKTQTVPNTDGPDLLTLQKAIHSSSTASSRPKEWRPEKLSDLQTQSQPLKSLRKLLHLSSSTNHPASSDPRFQPLTAQQAKNSFSEIRIHPLSQASGGSSNIRQEPTPKGRPALQLPGQMDPGWHVSSVTRSATEGPSYSEQLGAKSGPNGHPYNRTNRSRMPNLNDLKETAL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UTQ8-1", "uniprot_id": "CDKL5_MOUSE", "id": "Q3UTQ8-1", "name": "Cyclin-dependent kinase-like 5", "aln": "-MKIPNIG----NVMNKFEILG-----------------------VVGEGAYG----VVLKCRHKETHEIVAIKKFKDSEENEEVKETTLRELKMLRTLKQENIVELKEAFRRRGKLY---LVFEYVEKNMLELLEEMPNG---VPPEKVKSYIYQLIKAIHWCHKNDIVHRDIKPENLLISHN-DVLKLCDFGFARNLSEGNNANYTEYVATRWYRSPELLLGAP-YGKSVDMWSVGCILGELSDGQPLFPGESEIDQLFTIQKVLGPLPSEQMKLFYSNPRFHGLRFPAVNHPQSLERRYLGILNSVLLDLMKNLLKLDPADRYLTEQCLNHPTFQTQRLLDRSPSRSTKRKPYHVESSTLSNRNQSTKGAALQTHHRSNSKDIQNLSVGLPRAEEGLPANESFLNGNLAGATLSPMHTKTYQASTQPGSSSKDLTNNNIPHLLSPKEAKSKTEFDFNIDTKPSEGPGTKYLKSSTRSQQNRHSFMESSQSKAGTLQPSEKQSRHSYIDTIPQSSRSPSYRTKAKSHGALSDSKSVSNLSEARAQITETNTSRYFPSSCLDLNSPTSPTPTRHTDTRTLLSPSGRNNRNEGTLDSRRTTTRHSKTMEELKLPEHMDSSHSHSLSAPHESFSYGLGYTSPFSSQQRPHRHSMYVTRDKVRAKGLDGSLSIGQGMAARANSLQLLSPQPGEQLPPEMTVARPSVKESSREGASSFHTRQKSEGGVYHDPHSDDGTAPKENRHLYNDPVPRRVGSFYRVPSPRPDNSFHENNVSTRVSSLPSDSSSGTNHSKRQPGFDPWKSPENISHADQLKEKEKQGFFRSMKKKKKKTQTVPNTDGPDLLTLQKAIHSSSTASSRPKEWRPEKLSDLQTQSQPLKSLRKLLHLSSSTNHPASSDPRFQPLTAQQAKNSFSEIRIHPLSQATGGSSNIRQEPTPKGRPALQLPGSSLLRYNGWKHSRSRSSQPDEVIFLASHEKWKQ----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q12222-1", "uniprot_id": "YGK3_YEAST", "id": "Q12222-1", "name": "Glycogen synthase kinase-3 homolog YGK3", "aln": "MLKVNNVFGSNPNRMTKLEDEHYFIDDIVSIKNRQKSKMYVREGKRIGHGSFGTVTQSILSSNSIEWLGPYAIKRVVKSPKVQSLELEILQNIRHPNLVTLEFFFESHCTTKDGGHLYQKNFVMEYIPQTLSSEIHEYFDNGSKMPTKHIKLYTFQILRALLTLHSMSICHGDLKPSNILIIPSSGIAKVCDFGSAQRLDD--NTELKTYFCSRFYRAPELLLNSKDYTTQIDIWSLGCIIGEMIKGQPLFKGDSANSQLEEIAKLLGRFPKSSIKNSQE------LQDSLNDQKFKKFMHWFPSIEFFDVEFLLKVLTYDATERCDARQLMAHEFFDALRNETYFLPRGS------------------------------------SMPVHLP-----------------------------------------DLFN----------------------------------------------------------FSASEKRALGEYYNLIVPSLD--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*: *: * *.*:* :*.*::* :*... * ***:. .* : :.:: *:::: . :. * :.* : : : *:** :*:**: :.: . :.* :. :*.:::* * :*:::*: *. .* * *:**.*:** . .: *:**** *:.*.: *:: . *..:*:**:*****.: * ..:*:**:***:**: .***** *:* .** * *:** :*...:* . *: . :: . ::: :: . :::: ::*. *.::* :.* : * *:: * .*.: .:.* ** ** * :...**:: .* : * * ", "identical_positions": 100, "similar_positions": 135, "identity": "10.0%" }, { "cls_id": "homologset.agr.MGI:1278339", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O08560-1", "uniprot_id": "DGKZ_RAT", "id": "O08560-1", "name": "Diacylglycerol kinase zeta", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEPRDPSPEARS----------SDSESASASSS----------------GSERDADPEPD-----------------------KAPRRLTK-----------------------------------------------------------------------------------------------------------RRFPGLRLFG------------------------------------------------------------------------------------HRKAITKSGLQHLAPPPP-------------------------------------------TPGAPCGESERQIRSTVDWSESAAYGEHIWFETNVSGDFCYVGEQYCVAKMLPKSAPRRKCAACKIVVHTPCIGQLEK------------------------INFRCKPSFRESGSRNVREPTF--------------------------------VRHHWVHRRRQDGKCRHCGKGFQQKFTFHS-----KEIVAISCSWCKQAYHSKVSCFMLQQIEEPCSLGVHAAVVIPPTWILRARRP---QNTLKASKKKKRAS--------------------FKRRSSKKGPEEGRWRPFIIRPTPSPLMKPLLVFVNPKSGGNQGAKIIQSFLWYLNPRQVFDLSQGGPREALEMYRKVHNLRILACGGDGTVGWILSTLDQLR--LKPPPPVAILPLGTGNDLARTLNWGGGYTDEPVSKILSHVEEGNVVQLDRWDLRAEPNPEAGPEERDDGATDRLPLDVFNNYFSLGFDAHVTLEFHESREANPEKFNSRFRNKMFYAGTAFSDFLMGSSKDLAKHIRVVCDGMDLTPKIQDLKPQCIVFLNIPRYCAGTMPWGHPGEHHDFEPQRHDDGYLEVIGFTMTSLAALQVGGHGERLTQCREVLLTTAKAIPVQVDGEPCKLAASRIRIALRNQATMVQKAKRRSTAPLHSD-QQPVPEQLRIQVSRVSMHDYEALHYDKEQLKEASVPLGTVVVPGDSDLELCRAHIERLQQ---------------EPDGAGAKSPMCHPLSSKWCFLDATTASRFYRIDRAQEHLNYVTEIAQDEIYILDPELLG---ASARPDLPTPTSP-------------LPASPCSP--TPG-------------------------------------------------------------------------------------------------SLQGDAALPQGEELIEAAKRNDFCKLQELHRAGGDLMHRDHQSRTLLHHAVSTGSKEVVRYLLDHAPPEILDAVE-ENGETCLHQAAALGQRTICHYIVEAGASLMKTDQQGDTPRQRAEKAQDTELAAYLENRQHYQMIQREDQETAV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80UP3-1", "uniprot_id": "DGKZ_MOUSE", "id": "Q80UP3-1", "name": "Diacylglycerol kinase zeta", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEPRDPSPEGRS----------SDSESASASSS----------------GSERDAGPEPD-----------------------KAPRRLTK-----------------------------------------------------------------------------------------------------------RRFPGLRLFG------------------------------------------------------------------------------------HRKAITKSGLQHLAPPPP-------------------------------------------TPGAPCGESEEQIQSTVDWSESAVYGEHIWFETNVSGDFCYVGEQHCVAKMLPKSAPRKKCAACKIVVHTQCIKQLEK------------------------INFRCKPSFRESGSRNVREPTF--------------------------------VRHHWVHRRRQDGKCRHCGKGFQQKFTFHS-----KEIVAISCSWCKQAYHSKVSCFMMQQIEEPCSLGVHAAVVIPPTWILRARRP---QNTLKASKKKKRAS--------------------FKRRSSKKGPEEGRWRPFIIRPTPSPLMKPLLVFVNPKSGGNQGAKIIQSFLWYLNPRQVFDLSQGGPREALEMYRKVHNLRILACGGDGTVGWILSTLDQLR--LKPPPPVAILPLGTGNDLARTLNWGGGYTDEPVSKILSHVEEGNVVQLDRWDLRAEPNPEAGPEERDDGATDRLPLDVFNNYFSLGFDAHVTLEFHESREANPEKFNSRFRNKMFYAGTAFSDFLMGSSKDLAKHIRVVCDGMDLTPKIQDLKPQCIVFLNIPRYCAGTMPWGHPGEHHDFEPQRHDDGYLEVIGFTMTSLAALQVGGHGERLTQCREVLLTTAKAIPVQVDGEPCKLSASRIRIALRNQATMVQKAKRRSTAPLHSD-QQPVPEQLRIQVSRVSMHDYEALHYDKEQLKEASVPLGTVVVPGDSDLELCRAHIERLQR---------------EPDGAGAKSPMCHQLSSKWCFLDATTASRFYRIDRAQEHLNYVTEIAQDEIYILDPELLG---ASARPDLPTPTSP-------------LPASPCSP--TPG-------------------------------------------------------------------------------------------------SMQGDTALPQGEELIEAAKRNDCCKLQELHRAGGDLMHRDQKSRTLLHHAVSTGSKEVVRYLLDHAPPEILDAVE-ENGETCLHQAAALGQRTICHYIVEAGASLMKTDLQGDTPRQRAEKAQDTELAAYLENRQHYQMIQREDQETAV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13574-2", "uniprot_id": "DGKZ_HUMAN", "id": "Q13574-2", "name": "Diacylglycerol kinase zeta", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEPRDGSPEARS----------SDSESASASSS----------------GSERDAGPEPD-----------------------KAPRRLNK-----------------------------------------------------------------------------------------------------------RRFPGLRLFG------------------------------------------------------------------------------------HRKAITKSGLQHLAPPPP-------------------------------------------TPGAPCSESERQIRSTVDWSESATYGEHIWFETNVSGDFCYVGEQYCVARML-KSVSRRKCAACKIVVHTPCIEQLEK------------------------INFRCKPSFRESGSRNVREPTF--------------------------------VRHHWVHRRRQDGKCRHCGKGFQQKFTFHS-----KEIVAISCSWCKQAYHSKVSCFMLQQIEEPCSLGVHAAVVIPPTWILRARRP---QNTLKASKKKKRAS--------------------FKRKSSKKGPEEGRWRPFIIRPTPSPLMKPLLVFVNPKSGGNQGAKIIQSFLWYLNPRQVFDLSQGGPKEALEMYRKVHNLRILACGGDGTVGWILSTLDQLR--LKPPPPVAILPLGTGNDLARTLNWGGGYTDEPVSKILSHVEEGNVVQLDRWDLHAEPNPEAGPEDRDEGATDRLPLDVFNNYFSLGFDAHVTLEFHESREANPEKFNSRFRNKMFYAGTAFSDFLMGSSKDLAKHIRVVCDGMDLTPKIQDLKPQCVVFLNIPRYCAGTMPWGHPGEHHDFEPQRHDDGYLEVIGFTMTSLAALQVGGHGERLTQCREVVLTTSKAIPVQVDGEPCKLAASRIRIALRNQATMVQKAKRRSAAPLHSD-QQPVPEQLRIQVSRVSMHDYEALHYDKEQLKEASVPLGTVVVPGDSDLELCRAHIERLQQ---------------EPDGAGAKSPTCQKLSPKWCFLDATTASRFYRIDRAQEHLNYVTEIAQDEIYILDPELLG---ASARPDLPTPTSP-------------LPTSPCSP--TPR-------------------------------------------------------------------------------------------------SLQGDAAPPQGEELIEAAKRNDFCKLQELHRAGGDLMHRDEQSRTLLHHAVSTGSKDVVRYLLDHAPPEILDAVE-ENGETCLHQAAALGQRTICHYIVEAGASLMKTDQQGDTPRQRAEKAQDTELAAYLENRQHYQMIQREDQETAV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q2N7-1", "uniprot_id": "A0A8M9Q2N7_DANRE", "id": "A0A8M9Q2N7-1", "name": "Diacylglycerol kinase", "aln": "--------------------------------------------------MDALFNLRFRRKAV------EPSGRRRSSVSLPASK------ARRRSSAGLPSAGLAHRRRSSAQLQIGSIQPGLVLHRRGHFTRRKSSGGTACLTP-------------RFAIRRRQAAKHRS--IHAQLLGPSLLLASVVQMSED--------------HEPEDKSAEEYSS--------LSDTDCSQDEHE----------------QTGMDFETESDKCLTWLAQG-LLVGESIQPRPLIRAPRCLRRNSSHL-----------------------------------------------------------------------------------LPAEAVYRSPASYGLYGRYRRTSQVHNMGGLWAGKRSSLAARGSVALYRTSPPCWPDLSV----------------------------------SHTLQGTYYNPQIDTWSGFLSKAIAKSGLQHLSCQPS-------------------------------------------AAVLAKGETDREIRNTVDWSESAVYGEHIWFETNVSGDFCYVGEQHCYAKSLQKSVARKKCAACKIVVHSICIEQLEKLLDWNAPPQGEGLDEMPLKEPSFRINFRCKPSFRESGSRNIREQTWRRRAFRGRCALEQMRGAAAKCTAHTSNTQPAIVRHHWVHRRRQEGKCKQCGKGFQQKFAFHS-----KEIVAISCSWCKQAYHNKVTCFMLQQIEEPCSLGAHAAVIVPPTWIIRVRRP---QSSLKSSKKKKRTS--------------------FKRKSSKKGAEEARWKPFIVRPIPSQLMKPLLVFVNPKSGGNQGAKIIQTFLWYLNPRQVFDLSQGGPQEGLEMYRKVHNLRILACGGDGTVGWILSALDQLQ--LNPSPAVAVLPLGTGNDLARTLNWGGGYTDEPLSKILSHVEDGNIVQLDRWNLVVKPNPEAGPEERDEQVTDKLPLDVFNNYFSLGFDAHVTLEFHESREANPEKFNSRFRNKMFYAGTAFSDFLMGSSKDLAKHIKVVCDGTDLTSKVQDLKLQCLVFLNIPRYCAGTMPWGNPSEHHDFEPQRHDDGCIEVIGFTMTSLATLQVGGHGERLNQCREVTLTTFKSIPMQVDGEPCKLAPSVIHISLRNQANMVQKTKRRTSIPLLNDSQQPFPERLRIRVSRISMHDYEALHYDKEKLKEASIPLGLIVVPGDSDLETCRAHIERLQEDFVSCNPSLQRLVLQEGDGSKSKALSSQRLSPKWCFLDSTTADRFYRIDRAQEHLNYVTEISQDELFVLDPELVVTETVSTSPGMPDLVDSGE--VQSDPHKFAFPSSSSSPPNTPGPRV---------------------------------------AELQRKRVSSDSSVAEALAHSDSLRSAKPALCRAGGVHRSNTTAADFKPTSRFEKSAVNNANSVSVDSLIECVKKKDHQKLKELHKKGADLCVQDPAGRTLLHYAVEVGSKEIVKYIIDNAPTDILDVTEKENGETVLHKAASLCHRTICHYLVEAGASLMKTDLQGDTPKHRAEKAKDAELAAYLENRQHYQMIQREDQETAV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1RN59-1", "uniprot_id": "A0A8M1RN59_DANRE", "id": "A0A8M1RN59-1", "name": "Diacylglycerol kinase", "aln": "--------------------------------------------------MDTFFRRHFKRKEAGDGVHDDSCRHRRPSIAVPTSR------ARRRSSVGLPSSALTQRRRSSVQLQALPRINSSQPVHQKSSGRRRSSTTTLKANP-------------RFAVRRKKVGKLRN--IDTHLLGPSMLLASLIQMTQEEEDDEEGRSPLPGQVELKGSSSKFRSHTDVLLSEGDSDSDDSSEHSEERQYSRIRKECLEQADGSDWGVKESGVLCQQDCLPL-SVVAERVQAHPLIRVPRCLRRNSSHYG----------------------------------------------------------------------------------HAESGPHVRYCRSSQRRRRRRVSTISKAGSPWPGRGLPLPNRRS--------SCYRGPAT----------------------------------FNPLLGAYYDPRLESWSGFLSKAIAKAGVQDNAAQSG-------------------------------------------TITPAKSEPNKKICNTVDWTENAQLGQHVWFETSPAGDFCYVGESNCIAKSQQKSLPRHKCAACKISVHTECMNQLDK------------------------INFRCKPTFKDPGTKNVRETPN--------------------------------MNHHWVHRRRQDGKCRQCGKGFQQKFSFHS-----KDIVAISCSWCKQAYHNKVNCFMMQRIDEPCSLGAHAAVIIPPTWIIRMRRQ---QASLKSSKRRKRTS--------------------LKAKPSKKLEQDGKWRNFVVRAIPSQHMKPLLVFVNPKSGGNQGTKIIRTFMWYLNPRQVFDLTQGGPREGLEMYSKVPNLRILVCGGDGTVGWILSVLDELQ--LNPQPAVAVLPLGTGNDLARTLNWGGGYTDEPVSKILSQVEDGIIVQLDRWNLSVEANLEASDEDKDEQQTDKLPIDVFNNYFSLGFDAHVTLEFHESREAKPERFNSRLRNKMFYAGTAFSDFLMGSSKDLSKHIKVVCDGTDLTSKIQDMKVLCLLFLNIPRYCAGTMPWGNPSENNDFGPQKHDDGLIEVIGFTMTSMATLQVGGHGERLHQCKEVTLTTFKPIPVQVDGEPCRLAPSVIHITRRNQANMLQKTKRRISLPQLYD-QQPIAETVQIQVNRISMHDYEALHYDKEQLKEAAIPMGIITVPGNSDLETCRQHIERLHE---------------EGDGMNTDTLHMPKLSPKWCFLDCTTADRFYRIDRGQEHLNYVSEISQDELFILDPELVTKETVGTSPGMPGAMETVVGGCGCSNSTDQFAFPACSPGPSPLCRVNETHAESQPESVSEEIDMHVQSDPESPTNLGVYRVHETHAESQLESLSPESDSHVQSDPGSPTKSGLYRRGAKNKISSRSNTLEEDSVNVQRLDTVWNKSDQDSTNLLFDAVKSGNLEKLEQMHEEGADLTVQDHLGCTILHQAVILGHKEIVKFITENAPACILDVTEKSTGETALHKAAALCHRTICCYLVDAGASLMKTDLQGETPKMYAERTRDYELAEYLENQQHHQMIQRDDHETAV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q09103-1", "uniprot_id": "DGK2_DROME", "id": "Q09103-1", "name": "Eye-specific diacylglycerol kinase", "aln": "MQQQQQPSIDQLPEPTASTSNSATTKPTIATATTSTTTTSGNNFHQQLQATTAATMQRLRTTFTRSRTPTGAEMKMQNSLEVPKQVRSASFDEMQLESQRASSSLLKQQSSSSASADERSSEAGFLQVPLAAHQQRSHSFDSATASAGSDDSGTFLEVPRRLKARRSSSTKTPPPCIHCHYLEEYERRMTAEQRYFIDHRELTALSYSNTSSEASEDEDEVEGHNAEEEEEGSAAIEDAEEETTEAATEEADED-PRTEVESEHDHDPDDDAALEMDIRIGNMSQGSSIEESRARLPRQMRRHTIGSSSVTSASEDEGLEGSDNGSPHFGNTLLPPQPTTPCGITFTLSPTNGDYPSPPHLPLDPGSPPISPCSSNSGRLPALAPIISTPCSSADADDAGAAMGLPVRARRRSISRQEAIFVEPTGNSLENVSHEEVDNSNTKSSVDTADSLDEASTMATCGSPGAAGGSGASSSHHNAFVVRDIYLMVPDLKRDRAASVDSCFSKLSSNAKTEELQPSADGCFLTVPNINATRSRSVDIVLPTDEQARYKALSMTGSTVTYADGRTASASNSRRPIRIVPDWTENAVQGEHYWKPTSASGDLCCLN------EECIKSGQRMKCSACQLVAHHNCIPFVNE-----------------------KSTLACKPTYRDVGIRQYREQTT--------------------------------THHHWVHRKLEKGKCKQCGKFFPMKQAVQSKLFGSKEIVALACAWCHEIYHNKEACFNQAKIGEECRLGNYAPIIVPPSWIVKLPTKGNFKSSIRVSNKNNAASGSGGGGAGGGAGGGGGKSKKQTQRRQKGKEEKKEPRAFIVKPIPSPEVIPVIVFINPKSGGNQGHKLLGKFQHLLNPRQVFDLTQGGPKMGLDMFRKAPNLRVLACGGDGTVGWVLSVLDQIQPPLQPAPAVGVLPLGTGNDLARALGWGGGYTDEPIGKILREIGMSQCVLMDRWRVKVTPNDDVTDDHVDRSKPN-VPLNVINNYFSFGVDAHIALEFHEAREAHPERFNSRLRNKMYYGQMGGKDLILRQYRNLSQWVTLECDGQDFTGKLRDAGCHAVLFLNIPSYGGGTHPWN---DSFGASKPSIDDGLMEVVGLTTYQLPMLQAGMHGTCICQCRKARIITKRTIPMQVDGEACRVKPSVIEIELLNKALMLSKRKHGRGDVQVNP-----LEKMQLHILRVTMQQYEQYHYDKEMLRKLANKLGQIEIESQCDLEHVRNMLNTKFE----------------------ESISYPKVSQDWCFIDSCTAEHYFRIDRAQEHLHYICDIAIDELYILDHEAAT---MPQTPDQERSFAAFSQRQAQNERRQMDQAQGRGPGSTDEDLQIG-------------------------------------------------------------------------------------SKPIKVMKWKSPILEQTSDAILLAAQSGDLNMLRALHEQGYSLQSVNKNGQTALHFACKYNHRDIVKYIIASATRRLINMADKELGQTALHIAAEQNRRDICVMLVAAGAHLDTLDSGGNTPMMVAFNKNANEIATYLESKQGTQPVDGWLDD---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . : . : : :. : . . : ** : : ** . . * ::: :. . . .:. . * . **:*.* *:* * *. :**:* :. . ** * **:**:: .* *: ::: .: ***:::: * :: ** . .******: :.***::*** * * :.:* *:***::*:**:: **.* ** :* * * ** :*.:::**:**:: : ::: *::.: :* . : .* :. . : *:::. ** : *::**:********* *:: .* *********:****: .*:*: *. ***:*.*********:**.**::: *:* *.*.:***********:*.*********:.*** .: . * :*** : . .* :. :. * .: :*::*:*****:*.***::*****:***:**:****:****:*. . .*::: . ::*:: : : *** *:* *::* .::***** * .** **. : . *** :**:*:* .:. **.* ** : **::. : * :.**:*****.*:: .* *.* *:* *:.* *: * ::::: *::*::** ***** *:: : :* : : .:.*** * :: . .: :* .***:*. **.:::****.****:*: :*: **:::** * *. . .* : . . : :: ..: : *. :*. * .* : . * ** * . :::*::: *. ::: .: . *:* ** ** :* ** :* *** * . * *:** * . . *:* ***.:* * :: .: ", "identical_positions": 313, "similar_positions": 285, "identity": "19.07%" }, { "cls_id": "homologset.agr.MGI:1278340", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O09167-1", "uniprot_id": "RL21_MOUSE", "id": "O09167-1", "name": "Large ribosomal subunit protein eL21", "aln": "MTNTKGKRRGTRYMFSRPFRKHGVVPLATYMRIYKKGDIVDIKGMGTVQKGMPHKCYHGKTGRVYNVTQHAVGIIVNKQVKGKILAKRINVRIEHIKHSKSRDSFLKRVKENDQKKKEAKEKGTWVQLKRQPAPPREAHFVRTNGKEPELLEPIPYEFMA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P46778-1", "uniprot_id": "RL21_HUMAN", "id": "P46778-1", "name": "Large ribosomal subunit protein eL21", "aln": "MTNTKGKRRGTRYMFSRPFRKHGVVPLATYMRIYKKGDIVDIKGMGTVQKGMPHKCYHGKTGRVYNVTQHAVGIVVNKQVKGKILAKRINVRIEHIKHSKSRDSFLKRVKENDQKKKEAKEKGTWVQLKRQPAPPREAHFVRTNGKEPELLEPIPYEFMA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P20280-1", "uniprot_id": "RL21_RAT", "id": "P20280-1", "name": "Large ribosomal subunit protein eL21", "aln": "MTNTKGKRRGTRYMFSRPFRKHGVVPLATYMRIYKKGDIVDIKGMGTVQKGMPHKCYHGKTGRVYNVTQHAVGIIVNKQVKGKILAKRINVRIEHIKHSKSRDSFLKRVKENDQKKKEAKEKGTWVQLNGQPAPPREAHFVRTNGKEPELLEPIPYEFMA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3ZEK2-1", "uniprot_id": "D3ZEK2_RAT", "id": "D3ZEK2-1", "name": "Large ribosomal subunit protein eL21", "aln": "MTNTKGKRRGTRYMFSRPFRKHGVVPLATYMRIYKKGDIVDIKGMGTVQKGMPHKYYHGKTGRVYNVTQHSVGIIVNKQVKGKILAKRINVRIEHIKHLKSRDSFLKRVKENDQKKKEAKEKGTWVQLKRQPAPPREAHFVRTNGKEPGLLEPSPYGFMA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6A5T5-1", "uniprot_id": "A0A8I6A5T5_RAT", "id": "A0A8I6A5T5-1", "name": "Large ribosomal subunit protein eL21", "aln": "MTNTKGKRRGTRYMFSRPFRNHGVIPLATYIRIYKKGDIVDIKGMGTAQKGMPHKCYHGKTGRAYNVTQHAVGIIVNKQVKGKIPAKRINVRIEHTKHSKSRDGFLKRVKENDQKKKEAKEKGTWVQLKRQPVPPREAHFVRTNGKEPELLERSPYEFMA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0M392-1", "uniprot_id": "A0ABK0M392_RAT", "id": "A0ABK0M392-1", "name": "Large ribosomal subunit protein eL21", "aln": "MTNTKGKRRGTWYMFSRPFRKHGVVPLATYMRIYKKGDIVDIKGMGTVQKGMPHKCYHGKTGRVYNVTQHAVGIIVNKQVKGKIPAKRINVWFEHIKHSKSRDSFLKRVKENDQKKKEAKEKGTWVQLKRQPAPPREAHFVRTNGKEPELLEPSPYEFMA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3ZQ96-1", "uniprot_id": "D3ZQ96_RAT", "id": "D3ZQ96-1", "name": "Large ribosomal subunit protein eL21", "aln": "MTNTKVKRRGTRYVFSRPFRKHGVVPLVTYMRLYKKGDIVDIKGMGAAQKGMTHKCYHGKTVRVYNVTQHAVGIIVNKQVKGKILAKRINVWIEHIKHSKSRDSFLKQVKENDQKKEEAKEKGTWVQLSLQPAPPREAHFVRTNGKEPELLEPVP-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9V9M7-1", "uniprot_id": "Q9V9M7_DROME", "id": "Q9V9M7-1", "name": "Large ribosomal subunit protein eL21", "aln": "MTNSKGYRRGTRDMFSRPFRKHGVIPLSTYMRVFKIGDIVDIKGHGAVQKGLPYKAYHGKTGRIFNVTQHAVGVIVNKRVRGKILAKRVNVRIEHIHHSKCREDFLRRVKENERLLKEAKEKGQWVSLKRQPEQPKKAHFVKK-LEEPIALAPIPYEFIA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12672-1", "uniprot_id": "RL21B_YEAST", "id": "Q12672-1", "name": "Large ribosomal subunit protein eL21B", "aln": "MGKSHGYRSRTRYMFQRDFRKHGAVHMSTYLKIYKVGDIVDIKANGSIQKGMPHKFYQGKTGVVYNVTKSSVGVIINKMVGNRYLEKRLNLRVEHIKHSKCRQEFLERVKANAAKRAEAKAQGVAVQLKRQPAQPRESRIVSTEGNVPQTLAPVPYETFI", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q02753-1", "uniprot_id": "RL21A_YEAST", "id": "Q02753-1", "name": "Large ribosomal subunit protein eL21A", "aln": "MGKSHGYRSRTRYMFQRDFRKHGAVHLSTYLKVYKVGDIVDIKANGSIQKGMPHKFYQGKTGVVYNVTKSSVGVIINKMVGNRYLEKRLNLRVEHIKHSKCRQEFLERVKANAAKRAEAKAQGVAVQLKRQPAQPRESRIVSTEGNVPQTLAPVPYETFI", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* ::: * * :*.* **:**.: : **::::* *******. *: ***:.:* *:*** :***: :**:::** * .: **:*: .** :* *.*: **.:** * *** :* *.*. ** *:::::* . : * * * ", "identical_positions": 62, "similar_positions": 45, "identity": "38.75%" }, { "cls_id": "homologset.agr.MGI:1278342", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88803-1", "uniprot_id": "LECT2_MOUSE", "id": "O88803-1", "name": "Leukocyte cell-derived chemotaxin-2", "aln": "MIPTT-----------ILISAALLSSALAG--PWANICASKSSNEIRTCDS-YGCGQYSAQRTQRHHPGVDVLCSDGSVVYAPFTGKIVGQEKPYRNKNAINDGIRLSGRGFCVKIFYIKPIKYKGSIKKGEKLGTLLPLQKIYPGIQSHVHVENCDSSDPTAYL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A526-1", "uniprot_id": "D4A526_RAT", "id": "D4A526-1", "name": "Leukocyte cell-derived chemotaxin-2", "aln": "MFPTR-----------ILMSAALISTALAG--PWANICASRSSNEIRTCDS-YGCGQYSTQRTQRHHPGVDVLCSDGSVVYAPFTGKIVGQEKPYRNKNAINDGVRLSGRGFCVKIFYIKPIKYKGSIRKGEKLGTLLPLQKVYPGIQSHVHIENCDSSDPTAYL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O14960-1", "uniprot_id": "LECT2_HUMAN", "id": "O14960-1", "name": "Leukocyte cell-derived chemotaxin-2", "aln": "MFSTK-----------ALLLAGLISTALAG--PWANICAGKSSNEIRTCDR-HGCGQYSAQRSQRPHQGVDILCSAGSTVYAPFTGMIVGQEKPYQNKNAINNGVRISGRGFCVKMFYIKPIKYKGPIKKGEKLGTLLPLQKVYPGIQSHVHIENCDSSDPTAYL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F1W2-1", "uniprot_id": "E7F1W2_DANRE", "id": "E7F1W2-1", "name": "", "aln": "METNTYRIMRLDILFCFLVWAVLSCSCVRDRVKFGPLCSGNKDNTKRGCDVNYGCGHYGASRGSRKHMGLDIVCTDGAYVYAPFDVRIIGRAKPYGNNNAIDDGITLMGEGLCFKLFYVQPDLLSGTKFKYEKIGSLLPMQKVYPGITSHVHVQMCDKSDPTEYF", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* .. *: * * .:.: . :. :*:....* * ** :***:*.:.* .* * *:*::*: *: ***** *:*: *** *:***::*: : *.*:*.*:**::* .*. * **:*:***:**:**** ****:: **.**** *:", "identical_positions": 67, "similar_positions": 50, "identity": "40.61%" }, { "cls_id": "homologset.agr.MGI:1278343", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O75323-1", "uniprot_id": "NIPS2_HUMAN", "id": "O75323-1", "name": "Protein NipSnap homolog 2", "aln": "MAARVLRARGAAWAGGLLQRAAPCS----LLPRLRTWTSSSNRSREDSWLKSLFVRKVDPRKDAHSNLLAKKETSNLYKLQFHNVKPECLEAYNKICQEVLPKIHEDKH-YPCTLVGTWNTWYGEQDQAVHLWRYEGGYPALTEVMNKLRENKEFLEFRKARSDMLLSRKNQLLLEFSFWNEPVPRSGPNIYELRSYQLRPGTMIEWGNYWARAIRFRQDGNEAVGGFFSQIGQLYMVHHLWAYRDLQTREDIRNAAWHKHGWEELVYYTVPLIQEMESRIMIPLKTSPLQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O55126-1", "uniprot_id": "NIPS2_MOUSE", "id": "O55126-1", "name": "Protein NipSnap homolog 2", "aln": "MAARVLLAR-----GGLLRPAAQSA----FLPGLRTVTSSSHRAREDSWLKSLFVRKVDPRKDAHSNLLAKKETSSLYKLQFHNVKPECLDAYNKICQEVLPKIHEGKQ-YPCTLVGTWNTWYGEQDQAVHLWRYEGGYPALTEVMNKLKENQEFVNFRKARSDMLLSRKNQLLLEFSFWNEPVPRPGPNIYELRSYQLRPGTMIEWGNYWARAIRFRQDSNEAIGGFFSQIGQLYMVDHLWAYRDLQTREDIRNAAWHKHGWEELVYYTVPLIQEMESRIMIPLKTSPLQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9PU58-1", "uniprot_id": "NIPS2_DANRE", "id": "Q9PU58-1", "name": "Protein NipSnap homolog 2", "aln": "MATRVLHSS----CSGLYRAAGPARGKGHATAVIRSLSASHNRPREDSWFKSLFVRKVDPRKDAHSHLLAKKEDNNLYKIQFHNVKPECLEAYNKLCEDVLTNIHTDKA-YPCELVGTWNTWYGEQDQAVHLWRYRGGYPALTEVMSKLKNNKEFLEYRSERGKMLLSRRNQLLLEFSFWNEPVPRDGPNIYELRSYQLRPGTMIEWGNYWARAIGYRQHNREAVGGFFSQIGDLYMVHHLWAYKDLQSREDTRNAAWQHEGWDEVVYYTVPLIQHMESRIMIPLKNSPLK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VXK0-1", "uniprot_id": "NIPSN_DROME", "id": "Q9VXK0-1", "name": "Protein NipSnap", "aln": "----MLKLR------NLLAVGKSNN------NAVRSLSTTPSRNDSESWFSKLLVRKIEPTKESHSRMLSDKE--IIYALHTHNVRPDSMGSYLNNYKTTVALINEKKANLSCELVASWTVQVGDMDQCLHLWKYTGGFEKIDQAKEDLWNDPEYLSLMQERSKFLRSRHLQYLLAFSYWPQIASRTGKNIYEMRSYRLTPGTMIEWGNNWARAINYRKHNNEAFAGFFSQIGRLYNVHHIWCYKSLQDRKETREAAWRSPGWDECVAYTVPLIREMHCRVLAPTEFSPSQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* .* . :*: ::: * .:**:..*:***::* *::**.:*:.** :* :: ***:*:.: :* : : .:. *: * .* **.:*.. *: **.:***:* **: : :. ..* :: *::. . *..:* **: * ** **:* : ..* * ****:***:* ********* ***** :*:...**..******* ** *.*:*.*:.** *:: *:***: **:* * ******:.*..*:: * : ** :", "identical_positions": 112, "similar_positions": 92, "identity": "38.49%" }, { "cls_id": "homologset.agr.MGI:1278344", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V728-1", "uniprot_id": "G3V728_RAT", "id": "G3V728-1", "name": "", "aln": "MAPRLCIISAAARRLLRKPGPCVGDLAAARAVRFYSKDSEGSWFRSLFVHKVDPRKDAHSTLLSKKETSNLYKIQFHNVKPECLDAY-NSLTEAVLPKLHLDEDYPCSLVGNWNTWYGEQDQAVHLWRFSGGYPALMDCMNKLKTNKEYLEFRKERSKMLLSRRNQLLLEFSFWNEPQPRAGPNIYELRTYKLKPGTMIEWGNNWARAIKYRQENQEAVGGFFSQIGELYVVHHLWAYKDLQSREETRNAAWRKRGWDENVYYTVPLVRHMESRIMIPLKISPLQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O55125-1", "uniprot_id": "NIPS1_MOUSE", "id": "O55125-1", "name": "Protein NipSnap homolog 1", "aln": "MAPRLCIISAAARRLFTKPRPRAGDLAAAGAVRFYSKDSEGSWFRSLFVHKVDPRKDAHSTLLSKKETSNLYKIQFHNVKPECLDAY-NSLTEAVLPKLHLDEDYPCSLVGNWNTWYGEQDQAVHLWRFSGGYPALMDCMNKLKNNKEYLEFRKERSKMLLSRRNQLLLEFSFWNEPQPRAGPNIYELRTYKLKPGTMIEWGNNWARAIKYRQENQEAVGGFFSQIGELYVVHHLWAYKDLQSREETRNAAWRKRGWDENVYYTVPLVRHMESRIMIPLKISPLQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BPW8-1", "uniprot_id": "NIPS1_HUMAN", "id": "Q9BPW8-1", "name": "Protein NipSnap homolog 1", "aln": "MAPRLCSISVTARRLLGGPGPRAGDVASAAAARFYSKDNEGSWFRSLFVHKVDPRKDAHSTLLSKKETSNLYKIQFHNVKPEYLDAY-NSLTEAVLPKLHLDEDYPCSLVGNWNTWYGEQDQAVHLWRFSGGYPALMDCMNKLKNNKEYLEFRRERSQMLLSRRNQLLLEFSFWNEPQPRMGPNIYELRTYKLKPGTMIEWGNNWARAIKYRQENQEAVGGFFSQIGELYVVHHLWAYKDLQSREETRNAAWRKRGWDENVYYTVPLVRHMESRIMIPLKISPLQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F6NVH9-1", "uniprot_id": "NIPS1_DANRE", "id": "F6NVH9-1", "name": "Protein NipSnap homolog 1", "aln": "-----MMATARPLQLLNTQQHFLNNVLAAWLARGFANKSDEGWLSSMFAHKVDARKDAHSNLLSKKETSNLYKIQFHNVKPEYMEEY-NKLSDEVQKELHHDTDYPCEVVGSWNTWYGEQDQAVHLWRYSGGYPALTECLRKLNLNTAYLAFRKERSKMLLSRRNQLLLEFSFWNEPVPRSGSNIYELRSYQLLPGTMIEWGNHWARAIKYRQENNEAVGGFFTQIGDLYVVHHLWAYKDLQSREETRKAAWEKEGWDVSVHYTMPLIQKMESRIMIPMVHSPLQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VXK0-1", "uniprot_id": "NIPSN_DROME", "id": "Q9VXK0-1", "name": "Protein NipSnap", "aln": "--------MLKLRNLLAVGKS--NNNAVRSLSTTPSRNDSESWFSKLLVRKIEPTKESHSRMLSDKE--IIYALHTHNVRPDSMGSYLNNYKTTVALINEKKANLSCELVASWTVQVGDMDQCLHLWKYTGGFEKIDQAKEDLWNDPEYLSLMQERSKFLRSRHLQYLLAFSYWPQIASRTGKNIYEMRSYRLTPGTMIEWGNNWARAINYRKHNNEAFAGFFSQIGRLYNVHHIWCYKSLQDRKETREAAWRSPGWDECVAYTVPLIREMHCRVLAPTEFSPSQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .*: .: :.... .*: .::.:*::. *::** :**.** :* :: ***:*: : * *. . * . . : .*.:*..*.. *: **.:***:::**: : :. ..* : ** : :***::* **: * ** **:* : .* * ****:*:*:* *********:*****:**:.*:**..***:*** ** ***:*.**.**.*:***:***.. *** * **:**::.*..*:: * ** *", "identical_positions": 109, "similar_positions": 89, "identity": "38.25%" }, { "cls_id": "homologset.agr.MGI:1289147", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A4D7-1", "uniprot_id": "E2F7_RAT", "id": "D4A4D7-1", "name": "Transcription factor E2F7", "aln": "-MEVNCLTLKDLISPRQTRLDFAVEDAE--TAQKENIFVDRSRMTPKTPMKNEPIDLSKQRIFTPERSPITPVKLVDRQPQVEPWTPTANLKMLISAASPDIRDREKKKELFRPIENKGDAFVNSLQLDVVGDSAVDDYEK--RRPSRKQKSLGLLCQKFLARYPSYPLSTEKTTISLDEVAVSLGVERRRIYDIVNVLESLHLVSRVAKNQYGWHGRHSLPKTLRTLQRLGEEQKYEEQMACLQQKELDLMEYRFGERRKDGSPDPRDQHLLDFSESDYPSSSANSRKDKSLRIMSQKFVMLFLVSKTKIVTLDVAAKILIEESQDTPDHSKFKTKVRRLYDIANVLTSLALIKKVHVTEERGRKPAFKWIGPVDFSSIDEELLDVSASVLPELKKETYGQIRVCAKERLARYGSFNTVQTSEKIQRKVNSEPSSPQG-GKQGP-AYSLEIGSLAAIYRQKVEDSSQGEAFVNKRAAPPASVLD-----PTLPVDSEYCVKPLAQPVFSVAQTDLQAFSAQNGLNGQVGVPVPSAASDAETLKSALLASQPLVYVPSTSLFMLYGSVQEALSPESRSEEDGSGSDVPA--DLSLAPTAQKRLCEERNPLED-DEPAVKRQSREFEDSPLSLVMPKKPSNSTDLAFPVTTGNGRATPLEDACVKGQLPAAEDASGRAVPNGFIASECGNPSRNPDTEKSSNDNEITKDPSLLQYLYVQSPAGLNGFNMLLPGGQTPHAVAPSSAAMPSFGVPCMFLPSPGLGPFPVLYSPAIPGPISSAPGTLPNTGPMNFGLSTLASASHLLISPAAMVNPKSSTLPSADPQLRCQPPLNPNPVMPGSHGVIH-PESPGYMRHPVSMVKAEQSPAPATPKSIQRRHRETFFKTPGSLGDPAFRR-ERNQSRNTSSAQRRLEISSSGPD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6S7F2-1", "uniprot_id": "E2F7_MOUSE", "id": "Q6S7F2-1", "name": "Transcription factor E2F7", "aln": "-MEVNCLTLKDLISPRQTRLDFAIEDAE--NAQKENIFVDRSRMTPKTPMKNEPIDLSKQRIFTPDRNPITPVKPVDRQPQVEPWTPTANLKMLISAASPDIRDREKKKELFRPIENKEDAFVNSLQLDVAGDGAVDEYEK--QRPSRKQKSLGLLCQKFLARYPSYPLSTEKTTISLDEVAVSLGVERRRIYDIVNVLESLHLVSRVAKNQYGWHGRHSLPKTLRTLQRLGEEQKYEEQMACLQQKELDLMGYRFGERRKDGSPDPRDPHLLDFSEADYPSSSANSRKDKSLRIMSQKFVMLFLVSKTKIVTLDVAAKILIEESQDTPDHSKFKTKVRRLYDIANVLTSLALIKKVHVTEERGRKPAFKWIGPVDFSSIDEELLDVSASILPELKKEAYGQIRVCAKERLVRYGSFNTVHTSEKIQRKVSSEPSSPQG-ERQGS-AYSLEIGSLAAIYRQKVEDNSQEEAFVSNTAVPPASILD-----PALSMDSEYCVKPLAQPVFSVAQTDLPAFSAQNGPSGQVGVPVPSAASDTENLKPALLAGQPLVYVPSTQLFMLYGSVQEGLSPESRSEEDGGGSDVPA--DLSVTPSAQKRLCEERDPQEEEDEPAMKRQSQEFEDSPLSLVMPKKPSSSTDLACPVTMGNGSSPPLEDACVKGQLPAAEEVTGKAAPNCYVASECGNPARNPDTEKPSNENEITKDPSLMQYLYVQSPAGLNGFNMVLPGTQTPHTVAPSPAQLPSFGVPCMFLQSPGLGPFPVLYSPAIPGPISSAPGTHPNPGPMNFGLSTLASASHLLISPAAMVNPKPSTLPCTDPQLRCQPSLNLNPVMPGSHGVIH-PESPCYVRHPVSMVKAEQSPAPATPKSIQRRHRETFFKTPGSLGDPVFRRKERNQSRNTSSAQRRLEISSSGPD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96AV8-1", "uniprot_id": "E2F7_HUMAN", "id": "Q96AV8-1", "name": "Transcription factor E2F7", "aln": "-MEVNCLTLKDLISPRQPRLDFAVEDGE--NAQKENIFVDRSRMAPKTPIKNEPIDLSKQKKFTPERNPITPVKFVDRQ-QAEPWTPTANLKMLISAASPDIRDREKKKGLFRPIENKDDAFTDSLQLDVVGDSAVDEFEK--QRPSRKQKSLGLLCQKFLARYPSYPLSTEKTTISLDEVAVSLGVERRRIYDIVNVLESLHLVSRVAKNQYGWHGRHSLPKTLRNLQRLGEEQKYEEQMAYLQQKELDLIDYKFGERKKDGDPDSQEQQLLDFSEPDCPSSSANSRKDKSLRIMSQKFVMLFLVSKTKIVTLDVAAKILIEESQDAPDHSKFKTKVRRLYDIANVLTSLALIKKVHVTEERGRKPAFKWIGPVDFSSSDEELVDVSASVLPELKRETYGQIQVCAKQKLARHGSFNTVQASERIQRKVNSEPSSPYR-EEQGSGGYSLEIGSLAAVYRQKIEDNSQGKAFASKRVVPPSSSLDPVAPFPVLSVDPEYCVNPLAHPVFSVAQTDLQAFSMQNGLNGQVDVSLASAASAVESLKPALLAGQPLVYVPSASLFMLYGSLQEGPASGSGSERDDRSSEAPATVELSSAPSAQKRLCEERKPQEE-DEPATKRQSREYEDGPLSLVMPKKPSDSTDLASPKTMGNRASIPLKDIHVNGQLPAAEEISGKATANSLVSSEWGNPSRNTDVEKPSKENESTKEPSLLQYLCVQSPAGLNGFNVLLSGSQTPPTVGPSSGQLPSFSVPCMVLPSPPLGPFPVLYSPAMPGPVSSTLGALPNTGPVNFSLPGLGSIAQLLVGPTAVVNPKSSTLPSADPQLQSQPSLNLSPVMSRSHSVVQQPESPVYVGHPVSVVKLHQSPVPVTPKSIQRTHRETFFKTPGSLGDPVLKRRERNQSRNTSSAQRRLEIPSGGAD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5RIX9-1", "uniprot_id": "E2F7_DANRE", "id": "Q5RIX9-1", "name": "Transcription factor E2F7", "aln": "MQEVKCLTLKDLLGVRTLVNKTGSDDAASMNDHKENICMDRRKMTPLKSESLTAALNGHGKISSPEITHITPIKLTEKA-HPDPWTPTANLKMLINAASPDIRDREMKKTLFKPIENKGKIAEEEEEEELDDSCQYEALDESERRPSRKQKSLGLLCQKFLALYPDYPESSESINISLDEVATCLGVERRRIYDIVNVLESLMLVSRKAKNMYVWHGRSRLPQTLQGLLQAGRDQHYDLLMD---------------QREGNG--------LHAVQHVQNAHAASSRRKDKSLRIMSQKFVMLFLVSKTQTVTLDMAAKILIEEGQEESYDSKYKTKVRRLYDIANVLTSLNLIKKIHMREEKTRKPVFKWIGPGNFQS---------SSNSDDLRGQIS-NSGTERREKMARHSSFQVITAPPVNQRLISSAPSTPHRYSTDEPVDYSRKSGNNSAVCRLQFGDG----------------------------------VHPSVSPAVPSALASL-AMPLQADL-----MPVPASFS------------HPLAILPQTPLLMLY----------SGNISDG-------------ASSLRKR---ERSEEDDHQTTKCRRRSASIESD----TVESESLSSSTRRSPVCSPEGS--PWDEASFGG--LHEDDVAASSSKDALLS---------------------------PHYLYVPNTAGLNSFNFLLP-------AGHAQGGVPAVAMPYFVVQSP-------LIAGAMP--------TSSTEGAAGFSVPTVLSPAQFVMAGGAYG--VTEILQSPE-HHGNVPATTSSPRAE---------ESP----------KPAQTQTPVTPKEASLGS-KSFFETPGAFGSLVNQS----AARKRGSAQRRLDIGHTAAN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **:*******:. * . . :*. . :**** :** :*:* .. . . .: : :*: . ***:* .:: : :************.********** ** **:***** . :. : :: .. : :: :****************** **.** *:*. .*******..****************** **** *** * **** **:**: * : *.:*:*: * :*. :* * ... : . :::. **********************: ****:********.*: . .**:***************** ****:*: **: ***.****** :*.* :* :*: : : . ::::.*:.**:.: :. ** :.* **:* : . ** : *. :*: * :. *. *:* . *... * :.* *:. * . :.:.:: * :**. :*.: *:*** * . *. :.: :** **. :: : . :*:* . *.. .: .:. .*: * : * .: . * :: :. : : :: :** * ..****.**.:*. .. : . :*:..:* :.: ** * : *:* : .. *. .*.:. : * :::::. * .. * ..: : *. . .* *** * *: .*.***. . ::**:***::*. . : :*: .******:* ..:", "identical_positions": 292, "similar_positions": 232, "identity": "31.77%" }, { "cls_id": "homologset.agr.MGI:1289155", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A140UHW6-1", "uniprot_id": "A0A140UHW6_RAT", "id": "A0A140UHW6-1", "name": "tRNA (guanine(26)-N(2))-dimethyltransferase", "aln": "MSLARTILWLSRPLR-------------------PARSLCRAQFMERKAQEPPSP-----PTMEN------GTRSC-EERPPAAP-----VATVTEGAARISFPSANEVFYNPVQEFNRDLTCAVITEFARIHLGAKGIQIKVPGEKDLQKIAVDLSDQ---------EEE--TAGQNENLAPGDQPRTAAVGEICQEGLRVLEGLAASGLRSIRFALEVPGLQSVVANDASARAVELMHRNVELNGVAHLVQPNQADARMLMYQHQKASERFDVIDLDPYGSPAPFLDAAVQAVSDGGLLCVTCTDMAVLAGN-SGETCYSKYG-AMALKSRACHEMALRIVLHSLDLHANCYQRYIVPLLSISADFYVRVFVRVFTGQAKVKSSASKQALVFQCVGCGAFYLQRLG----KASGDPGGRVKFSAACGPPVSPECEHCGQRHQLGGPMWAEPIHDLDFVGQVLEAVTTNPGR----FHTSTRIQGVLSVVTEELPDVPLYYTLDQLSSTVHCNTPRLLQLRSALLHAGFRVSLSHACKNAVKTDASPEALWDIMRCWEKECPVKRERLSESSPAFRILAVEP-----RLKANF--------NIREDANPSSRQRGLKRFQANPEANWGPRPRARPGGKAASEGLAERRRLLQNKRKEPAEDPAQRAARLKTFPCKRFKEGTCQLGDQCCYSHSPAAPVASGDIPITDCPETTTKLSPEPEAAHGSIPGPGVD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3TX08-1", "uniprot_id": "TRM1_MOUSE", "id": "Q3TX08-1", "name": "tRNA (guanine(26)-N(2))-dimethyltransferase", "aln": "MSLARTILWLSRPLR-------------------PAHSLCRAQFMERKAQKPPSP-----PAMEN------GTRSW-EERPPADP-----VATVTEGAAKIVFPSANEVFYNPVQEFNRDLTCAVITEFARIHLGAKGIQIKVPGEKDSEKIAVDLSDQ---------EEE--TAGKNENLAPGDWPRTAAVGEICEEGLRVLEGLAASGLRSIRFALEVPGLQSVVANDASARAVELMHRNVELNGVAHLVQPNQADARMLMYQHQKAPERFDVIDLDPYGSPAPFLDAAVQAVSDGGLLCVTCTDMAVLAGN-SGETCYSKYG-AMALKSRACHEMALRIVLHSLDLHANCYQRYIVPLLSISADFYIRVFVRVFTGQAKVKSSASKQALVFQCVGCGAFYLQRLG----KASGDPGGRIKFSAACGPPVTPECEHCGQRHQLGGPMWAEPIHDLDFVGRVLDAVTTNPGR----FHTSMRIQGVLSVVTEELPDVPLYYTLDQLSSTIHCNTPRLLQLRSALLHAGFRVSLSHACKNAVKTDAPPEALWDIMRCWEKECPVKRERLSESSPAFRILAVEP-----RLKANF--------NIREDANPSSRQRGLKRFQANPEANWGPRPRARPGGKAASEDLAGRRRLLQNKRKEPAEDPAQRAARLKTFPCKRFKEGTCQLGDQCCYSHSPAAPVASGDIPIEECPETTTKISPGPKAAAGGIPGPGVD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NXH9-1", "uniprot_id": "TRM1_HUMAN", "id": "Q9NXH9-1", "name": "tRNA (guanine(26)-N(2))-dimethyltransferase", "aln": "--MQGSSLWLSLTFR-------------------SARVLSRARFFEWQSPGLPNT-----AAMEN------GTGPYGEERPREVQ-----ETTVTEGAAKIAFPSANEVFYNPVQEFNRDLTCAVITEFARIQLGAKGIQIKVPGEKDTQKVVVDLSEQ---------EEEKVELKESENLASGDQPRTAAVGEICEEGLHVLEGLAASGLRSIRFALEVPGLRSVVANDASTRAVDLIRRNVQLNDVAHLVQPSQADARMLMYQHQRVSERFDVIDLDPYGSPATFLDAAVQAVSEGGLLCVTCTDMAVLAGN-SGETCYSKYG-AMALKSRACHEMALRIVLHSLDLRANCYQRFVVPLLSISADFYVRVFVRVFTGQAKVKASASKQALVFQCVGCGAFHLQRLG----KASGVPSGRAKFSAACGPPVTPECEHCGQRHQLGGPMWAEPIHDLDFVGRVLEAVSANPGR----FHTSERIRGVLSVITEELPDVPLYYTLDQLSSTIHCNTPSLLQLRSALLHADFRVSLSHACKNAVKTDAPASALWDIMRCWEKECPVKRERLSETSPAFRILSVEP-----RLQANF--------TIREDANPSSRQRGLKRFQANPEANWGPRPRARPGGKAADEAMEERRRLLQNKRKEPPEDVAQRAARLKTFPCKRFKEGTCQRGDQCCYSHSPPTPRVSADA-APDCPETSNQTPPGPGAAAG----PGID", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QGD9-1", "uniprot_id": "F1QGD9_DANRE", "id": "F1QGD9-1", "name": "tRNA (guanine(26)-N(2))-dimethyltransferase", "aln": "-MLACTVLQLSLKCSGLSSAFPKNRSLLQILPTGLTCVFTKFRTMDSNKQSQDSSSITTDEPMQDKNIQHPSSSTESNQTPSTDPGLLPGETVVREGKAAILFPNANEVFYNPVQEFNRDLTCAVITEFARDQLAQRGVRILVPGEKD--RVVVQLSEDKNGAGDQEAPEQPEQEHPKEEEAAEKEYITATVGERCEQGLRVLEGLAASGLRSVRFALEVPGLKSITANDYSAKAAALIARNAQHNNVTHILQASQRDASMVMYEARGRKERYDVIDLDPYGSPSPFLDSAVQAVSEGGLLCITCTDMAVMAGN-SGETCYSKYG-SVSIKSKYCHEMALRIILHSLDQRAAVYQRYIEPLLSVSVDFYIRVFVRVKTGQVVVKNSASKQALVYNCVGCGAFHLQRMG----KRIN-QGKHMKYSAATGPPVGPNCEHCGQRHQLGGPAWAEPLHDINFVQKVLGAVSGNPTR----FRTSKRIEGMLSMVTEELQDVPLYYTLDHLSSTVHRSTPPMMQFRSALLHAGYRVSFSHACKNAVKTDAPAGVLWDIMRCWERSNPVKRERLSETSPAHHILSKET-----TLEACF--------EIREDANPQSRKRHLTRFQENPQANWGPKARAKAGGGIASE-LEDKRKQFQGKRKKP----ITHSSQLKSFPCKKFRKGACTLGDKCCYSHDLEK-------------EAEEKMD----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VK89-1", "uniprot_id": "TRM1_DROME", "id": "Q9VK89-1", "name": "tRNA (guanine(26)-N(2))-dimethyltransferase", "aln": "--------------------------------------------MEVDEEKPQII----------------------AENPN--------ENVIRERNAEIVS--GGNVFYNPVQEFNRDLSIAALNVYRQRLTKER-------SEKALKKQRKKVKEQ---------------EDEKTTPVPEDPP-VYEAGTRYEDGLRILEALAATGLRSIRYAQEIAGVRQIVANDLSRQAVASINTNIRHNKVEELIEPSHSDAMTLMYLSTQPEKRFDAVDLDPYGCPNRFLDGAMQCLVDGGLLLVTATDMAVLAGN-APEACYVKYG-SVPLRMKCCHEMALRILLHCIESHANRYGKYIEPLLSISADFYIRIFVRVYVGQAQCKLSMSKQSWIYQCTGCETFTLQPLGITKPNPTAGNPQQLKFGIPTGPAVNSQCEHCGHRHHLGGPIWSAPIHNPEFVQDLLTAVQETTLQS---LGTQRRIVGVLSMVQEELQDVPLYYTPDKLCCVLKLEIVPMLKFRSAILHAGYRVSYSHASKNSLKTNAPPAVLWDILRSWSKRHPVNPERMIPGSPLAAILSKEC-----TAVYEFD-------ELHPEANPKSRKSALSRFQENPTPHWGPGTRATIMIG-DNKLPKSYRNQNKKQRHKASEQQAEDDQQDTPQAVDEYDGDVEHLPKQPKLEATA--------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P15565-1", "uniprot_id": "TRM1_YEAST", "id": "P15565-1", "name": "tRNA (guanine(26)-N(2))-dimethyltransferase, mitochondrial", "aln": "---MEGFFRIPLKRAN-------------------LHGMLKAAISKIKANFTAYG----------------------APRINIED-----FNIVKEGKAEILFPKKETVFYNPIQQFNRDLSVTCIKAWDNLYGEECGQKRN--NKKSKKKRCAETNDD---------------SSKRQKMGNGSPKEAVGNSNRNEPYINILEALSATGLRAIRYAHEIPHVREVIANDLLPEAVESIKRNVEYNSVENIVKPNLDDANVLMYRNKATNNKFHVIDLDPYGTVTPFVDAAIQSIEEGGLMLVTCTDLSVLAGNGYPEKCFALYGGANMVSHESTHESALRLVLNLLKQTAAKYKKTVEPLLSLSIDFYVRVFVKVKTSPIEVKNVMSSTMTTYHCSRCGSYHNQPLGRISQREGRNNKTFTKYSVAQGPPVDTKCKFCEGTYHLAGPMYAGPLHNKEFIEEVLRINKEEHRDQDDTYGTRKRIEGMLSLAKNELSDSPFYFSPNHIASVIKLQVPPLKKVVAGLGSLGFECSLTHAQPSSLKTNAPWDAIWYVMQKCDDE-KKDLSKMNPNTTGYKILSAMPGWLSGTVKSEYDSKLSFAPNEQSGNIEKLRKLKIVRYQENPTKNWGPKARPNTS------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : * * * *****:*:*****: : :. : . .:* : . .:: . . . : :.:**.*:*:***::*:* *:. ::.: *** .*. : * . * * .:::.. ** :** :::..:****** *:*.*:*.: :***: :*.**::*:*** * *: ** : : . ** ***::*: :. * * : : ****:* ***:*:**:* .. * *. ::* * :: * :* . *:. . **.* .:*:.* ::*.** :: *:*: :*: :* * ** *:**: :** * *:*:: :::...:: . : :. :.: .:. * :** .::**:*. .:* ::: . . .:: :. **: : : . *: : *:* ** :*** .*. ", "identical_positions": 128, "similar_positions": 160, "identity": "17.46%" }, { "cls_id": "homologset.agr.MGI:1289156", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LJZ8-1", "uniprot_id": "A0ABK0LJZ8_RAT", "id": "A0ABK0LJZ8-1", "name": "", "aln": "MKEAGKHFSGPKVIATMEGISNFKTPNKLSEKRKSVLCSTPCVNIPASPFMQKLGFGTGVSVYLMKRSPRG-LSHSPWAVKKINPLCDDHYRTVYQKRLTDEAKILKNLNHPNIVGYRAFTEASDGSLCLAMEYGGEKSLNDLIEERNKDSGSPFPAAVILRVALHMARGLKYLHQEKKLLHGDIKSSNVVIKGDFETIKICDVGVSLPLDENMTVT---DPEACYIGTEPWKPKEALEENGIITDKADMFAFGLTLWEMMTLCIPHINLPD----------------------------------------------------DDDDEDATFDESDFDDEA----------------YYAALGTRPSIN-MEELDESYQKVIELFCVCTNEDPKDRPSAAHIVEALELDGQCCGLSSKHSLYGNC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JJ78-1", "uniprot_id": "TOPK_MOUSE", "id": "Q9JJ78-1", "name": "Lymphokine-activated killer T-cell-originated protein kinase", "aln": "----------------MEGINNFKTPNK-SEKRKSVLCSTPCVNIPASPFMQKLGFGTGVSVYLMKRSPRG-LSHSPWAVKKISLLCDDHYRTVYQKRLTDEAKILKNLNHPNIIGYRAFTEASDGSLCLAMEYGGEKSLNDLIEERNKDSGSPFPAAVILRVALHMARGLKYLHQEKKLLHGDIKSSNVVIKGDFETIKICDVGVSLPLDENMTVT---DPEACYIGTEPWKPKEALEENGIITDKADVFAFGLTLWEMMTLCIPHVNLPD----------------------------------------------------DDVDEDATFDESDFDDEA----------------YYAALGTRPSIN-MEELDDSYQKAIELFCVCTNEDPKDRPSAAHIVEALELDGQCCGLSSKH------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96KB5-1", "uniprot_id": "TOPK_HUMAN", "id": "Q96KB5-1", "name": "Lymphokine-activated killer T-cell-originated protein kinase", "aln": "----------------MEGISNFKTPSKLSEKKKSVLCSTPTINIPASPFMQKLGFGTGVNVYLMKRSPRG-LSHSPWAVKKINPICNDHYRSVYQKRLMDEAKILKSLHHPNIVGYRAFTEANDGSLCLAMEYGGEKSLNDLIEERYKASQDPFPAAIILKVALNMARGLKYLHQEKKLLHGDIKSSNVVIKGDFETIKICDVGVSLPLDENMTVT---DPEACYIGTEPWKPKEAVEENGVITDKADIFAFGLTLWEMMTLSIPHINLSN----------------------------------------------------DDDDEDKTFDESDFDDEA----------------YYAALGTRPPIN-MEELDESYQKVIELFSVCTNEDPKDRPSAAHIVEALETDV---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DHU8-1", "uniprot_id": "TOPK_DANRE", "id": "Q6DHU8-1", "name": "Lymphokine-activated killer T-cell-originated protein kinase homolog", "aln": "------------MEASKESPSAFKTPCKPAKVKSPVNACGTPVTIPASPFMKKLGCGTGVNVYLMNRMGK--QTHSPWAIKKINSKCAQGQVSVYQKRLCEEAKILKDLKHPNIVGFRAFTTAKDGSKCLAMEFGGEQSLNDLIEKRREEGLQAFPVDTIEKVALHVARGLLYLHNEKKLLHGDMKSCNVVIKGDFESIKICDVGVSLPLDENMQVS---DPKAHYIGTEPWKPKEALED-GVITDKADIFAYGLTLWEMMTLSVPHLEMLDTEG-------------------------------------------------DEDDDDESFEE-DFDEDA----------------YYERLGSRPALD-AVTLGGSYQRMVELFCLCTEEDPQKRPSAAHIVQVLESNSQLSKQNTEVIVID--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VX24-1", "uniprot_id": "Q9VX24_DROME", "id": "Q9VX24-1", "name": "Protein kinase domain-containing protein", "aln": "----------------MDTPRRKLRNLHLENVQN----SSTPINVPPSPMMKTLGHGTGIRVYRLDRSPRLGEIRSPWAVKRITQNMRVKKDTLFNERIVHEADILRKLKHPNIVGFRGVITNDEGINTLALEMCT-TSLGSILEERHDEDLGPLPAKHTYKMIMDVAQALDFLHNEAHLMHGDLKSFNVLVKGEFEICKLCDFGVSLPLDEQGEVNFLKNPGLRYVGTNLWCAPEVIDEVDVIDSKADIFSFGLVIYETLALVPPHTLELDAALGEDMDSSHDLPTDTDKLQCKQLDFSSDENKNGLPSAMEEHTDNDMSQDYDEEDDEEEKEEEEEDDEEDDDTKENDISYFTLNNLHSAYGTRPPLPVAFQLSDDYNCVVELFYLCTNALSEDRPAAKTIWQCLENNGANVATESD-------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : :. . . :.:*.**:*:.** ***: ** :.* : :****:*:*. :::::*: .**.**:.*:****:*:*.. .:* **:* **..::*:* . . .:*. :: :.:*:.* :**:* :*:***:** **::**:** *:**.********: *. :* *:**: * . *.::: .:* .***:*::**.::* ::* ** : *: *:: :* : *:: : *:**.: *. .*: :*** :**: .:.**:* * : ** : ", "identical_positions": 105, "similar_positions": 112, "identity": "24.65%" }, { "cls_id": "homologset.agr.MGI:1289160", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4AAE2-1", "uniprot_id": "D4AAE2_RAT", "id": "D4AAE2-1", "name": "", "aln": "MYGKSLARVLPFLLSLQLTVFYPTTAVEIYTSGALEAVNGTDIRLKCTFSSFAPVGDALT-VTWNFRPRDGGREQFVFYYHMDPFRPMSGRFKDRVVWDGNPERYDVSIMLWKLQFDDNGTYTCQVKNPPDVDGLIGTIRLSVVHTVPFSEIYFLAVAIGSACALMIIIVIVVVLFQHFRKKRWAERADKSEGTKSKEEEKLNQGTKVSVYVEDTD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70255-1", "uniprot_id": "MPZL2_MOUSE", "id": "O70255-1", "name": "Myelin protein zero-like protein 2", "aln": "MYGKSPALVLPLLLSLQLTALCPTEAVEIYTSGALEAVNGTDVRLKCTFSSFAPVGDALT-VTWNFRPRDGGREQFVFYYHMDPFRPMSGRFKDRVVWDGNPERYDVSILLWKLQFDDNGTYTCQVKNPPDVDGLVGTIRLSVVHTVPFSEIYFLAVAIGSACALMIIVVIVVVLFQHFRKKRWADRADKAEGTKSKEEEKLNQGNKVSVFVEDTD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60487-1", "uniprot_id": "MPZL2_HUMAN", "id": "O60487-1", "name": "Myelin protein zero-like protein 2", "aln": "MYGKSSTRAVLLLLGIQLTALWPIAAVEIYTSRVLEAVNGTDARLKCTFSSFAPVGDALT-VTWNFRPLDGGPEQFVFYYHIDPFQPMSGRFKDRVSWDGNPERYDASILLWKLQFDDNGTYTCQVKNPPDVDGVIGEIRLSVVHTVRFSEIHFLALAIGSACALMIIIVIVVVLFQHYRKKRWAERAHKVVEIKSKEEERLNQEKKVSVYLEDTD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PI84-1", "uniprot_id": "A0A8M1PI84_DANRE", "id": "A0A8M1PI84-1", "name": "", "aln": "-MRRMWIYLSSALCALVFTGVYQVEGMEVFTSSELEAVNGTEIRLKCTFKSNRPLSEERTSVSWSFMPLGKTKEEPFFHYQGHAYLPPGGLFKDHVVWSGDVMKGDGSITLQDVQFSFNGTYSCQVLNPPDIQGFAGEIKLRVVQKVSFSEIGILAIAVGGSIGVILLILIIYIVVRVFRRR----EEDMTVET---EDHRLKDQVL---------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * .: :* . .:*::** *******: ******.* *:.: * *:*.* * . *: .*:*: ..: * .* ***:* *.*: : * ** * .:**. ****:*** ****::*. * *:* **:.* **** :**:*:*.: .::::::*: ::.: :*:: . . *:.:*:: ", "identical_positions": 72, "similar_positions": 66, "identity": "33.33%" }, { "cls_id": "homologset.agr.MGI:1289164", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4V8I2-1", "uniprot_id": "CNDH2_RAT", "id": "Q4V8I2-1", "name": "Condensin-2 complex subunit H2", "aln": "------------------------------------------------------------------------------------------MNFIEAALLIQGSACVYSKKVEYLYSLVYQALDFISGKRRAKQLSL---------VQEDGSNRAVNSGTP-CETEDEFLSL---------DDFPDSRANVDLKNDQASSELLIIPLLPMALVAPDEVEKSSNPLYS---CQGEVLASRKDFRMNTCTPDP---RGSFMLDPVGMCPVEP---VDVHPMPRSQKDAEEAEEQPMAVSRNGSPVSVRSISQEP----DGPALSSG---------------------DEDAEDVAELPEV-----ALEPAEPRTSQQTAILPRRYMLRER---QGAPEPASQPQETPDPWQS-------LDPFDSL-DSKLFQKGK--------------------------------------------------------------------PYSVPPGVEEAPGQKRKRKGATKLQDFHQWYLDA----------------------------------------YAEHPDGRRARRKGPSFADMEVLYWKHVKEQLETLQKLRRRK---MTERWLPGAKQDLWPAEEERLEEPLEDLGVADDFLEAEEYVEESEGVMPREAAGLDA-----------------------------------EAIPES-LKYEELVRRNVELFIATSQKFIQETELS-------------------QRIRDWEDTIQPLLQEQEQHVPFDIHTYGDQLVSRFPQLNEWCPFAELVAGQPAFEVCRSMLASLQLANDYTVEITQQPG-----LEAAVDTMSLRLLT---------------------------HQRAHMRFQTYAAPSMAQP-------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BSP2-1", "uniprot_id": "CNDH2_MOUSE", "id": "Q8BSP2-1", "name": "Condensin-2 complex subunit H2", "aln": "--------------------------------------MEDVEVRFAHLLQPIRDLTKN--WEVDVAAQLGEYLEELDQICISFDEGKTTMNFIEAALLIQGSACVYSKKVEYLYSLVYQALDFISGKRRAKQLSL---------VQEDGSKKTVNSETP-CETENEFLSL---------DDFPDSRANVDLKNDQASSELLIIPLLPMALVAPDEVEKNSSPLYS---CQGDILASRKDFRMNTCMPNP---RGCFMLDPVGMCPVEPVVPVEPYPMSRSQKDPEDAEEQPMEVSRNGSPVPVPDISQEP----DGPALSGG---------------------EEDAEDGAEPLEV-----ALEPAEPRTSQQSAILPRRYMLRER---QGAPEPASRLQETPDPWQS-------LDPFDSL-ESKVFQKGK--------------------------------------------------------------------PYSVPPGVEEAPGQKRKRKGATKLQDFHKWYLDA----------------------------------------YAEHPDGRRARRKGPTFADMEVLYWKHVKEQLETLQKLRRRK---INERWLPGAKQDLWPTEEDRLEESLEDLGVADDFLEPEEYVEEPAGVMPEEAADLDA-----------------------------------EAMPES-LRYEELVRRNVELFIATSQKFIQETELS-------------------QRIRDWEDTIQPLLQEQEQHVPFDIHIYGDQLASRFPQLNEWCPFSELVAGQPAFEVCRSMLASLQLANDYTVEITQQPG-----LEAAVDTMSLRLLT---------------------------HQRAHTRFQTYAAPSMAQP-------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6IBW4-1", "uniprot_id": "CNDH2_HUMAN", "id": "Q6IBW4-1", "name": "Condensin-2 complex subunit H2", "aln": "--------------------------------------MEDVEARFAHLLQPIRDLTKN--WEVDVAAQLGEYLEELDQICISFDEGKTTMNFIEAALLIQGSACVYSKKVEYLYSLVYQALDFISGKRRAKQLSS---------VQEDRANGVASSGVP-QEAENEFLSL---------DDFPDSRTNVDLKNDQTPSEVLIIPLLPMALVAPDEMEKNNNPLYS---RQGEVLASRKDFRMNTCVPHP---RGAFMLEPEGMSPMEP---AGVSPMPGTQKDTGRTEEQPMEVSVCRSPVPALGFSQEPGPSPEGPMPLGGG-------------------EDEDAEEAVELPEASAPKAALEPKESRSPQQSAALPRRYMLRER---EGAPEPASCVKETPDPWQS-------LDPFDSL-ESKPFKKGR--------------------------------------------------------------------PYSVPPCVEEALGQKRKRKGAAKLQDFHQWYLAA----------------------------------------YADHADSRRLRRKGPSFADMEVLYWTHVKEQLETLRKLQRRE---VAEQWLR-------PAEEDHLEDSLEDLGAADDFLEPEEYME-PEGADPREAADLD-------------------------------------AVPMS-LSYEELVRRNVELFIATSQKFVQETELS-------------------QRIRDWEDTVQPLLQEQEQHVPFDIHTYGDQLVSRFPQLNEWCPFAELVAGQPAFEVCRSMLASLQLANDYTVEITQQPG-----LEMAVDTMSLRLLT---------------------------HQRAHKRFQTYAAPSMAQP-------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5RH01-1", "uniprot_id": "CNDH2_DANRE", "id": "Q5RH01-1", "name": "Condensin-2 complex subunit H2", "aln": "--------------------------------------MDSVETRYAHLLQPLRDLTKN--WDIDLASQLGEYLEELDQMTISFDGGKTMMNFAEAALLIQGSTCIYGRKVELLHTLVFQTLDYISNKNKKRDKQG---------SSSDGNQEQAPSGSEGDGCEFDEIEQ---------DENVNT-HNITMKDPTEP--VRIIRLPPESLIPAESHEKQKYPLLS---LKGELLGSCKDFRINTFTMDE---AGLMRLGSNTHFLKG---------VAEVQRDFSVHLPEPLQIEG------------------EAAAANGG--------------------YDEEVDGGAEVLPP-LEDHGMEVESDEWVERHEAPSEGRMLRPRPAVQPVSEEPKQLKETVDPWKL-------HDPYATFGEDKPLKAGK--------------------------------------------------------------------CYKVPAGLDES--GKRKRKGPSKLQDFGTWFNKA----------------------------------------FETAD---RKLKNGPTFPDLNYIFVSKMDQRLKVQRQMLRKRGVFVSDEELKKTYLE--PENVEDQVEVIRHPDADGDDYSDEEHDNLADDLEPAEHLDDQEQIF--------------------------------QDLHMSRMSYEDLVKKSVDLFLVNSQKYAQETALS-------------------RRVKDWEDSINPHLAAQEISPAFDIHEYGDRIVHALSNVGVKKSFAFVVRGKENTEACRYMLAALQLANDYTVEVDKVDG-----LDCSVDTMELTLLT---------------------------TQRAHERLKTYNATAATDIP------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8INL2-1", "uniprot_id": "Q8INL2_DROME", "id": "Q8INL2-1", "name": "Condensin-2 complex subunit H2 C-terminal domain-containing protein", "aln": "MERILPEEAEAAYLSEAREQILEIAKNRPGTQVAKCIRAYDEQQDLASLVVLLEELSKNTDYSTDLRISLGYYIEELLRHCLGRNDVSRRSAIVAAGSALQYCGKIYGDRVEYLCQVVEHQIEALLTSELQKETPSGSAAPEKNERRPEETRKRHPKKLTNKEVDPYLLTLEPKRFKTMSDDKRFNAAGFVKCTRNRTIEYLYQDHTPPNLWKHAPIVDPHNPYDQDEKKQYKMFTYHVEHRYNTLLPDIPFERLNLIKEYVHTNQVNTTEILNEHMTTKEYLDEYIALENQMLAARYGAIVTRRRRLVDSARFMEDNLDEGLAKKMCMDKNLPMDTNETVLIDQSLVDENSRSLTTAESTMGISQAENSTLKSSEVEATLSVSHIENSLSDSQEENPPLSSTLAINESSVLDSTRVDPIKDLTLDELLLIDSGISMEELSDIQMHTAGQSFDDEGVVLSDLEDQRQLSPMLQMVSPSMEAKTLNIIEMDADLIMNVPREVSYPILLNVMGLPIKRLRRKCIFKLPPEFDLFRQARLPIKREGQQKSPTTPRTVLQIGREAPQNEREPGSPCSLEFDEDLNFLGFRQRRPTFDSGFDIEEPRVSSCVSTIGEVKTELEDEIEANTNNLTDASASDALNENVNDTKESGLGDSLAQELNASTEPNAENNTANSSQLEVTATESSGTLSGLETTVDLGMESALVSSVLDLSTEPSAMDSNIINVTQPDNSDLEISTVQDQDTLHDEADANDLSAETPNPIADSAVDDCSLIRDWHRRLAPALEAAHERQNFNIKDLGTEILDICKAGNRTATLADVMADKDPSIMCRYMLASLVLTNHGNVSLDFENRDKSKPIDMSQFRMHLKSMKRMEINPEDDVGNINAAQSKSTPRSKQLNDSAHKPRTSTTASAPTKRKSAENSLSEVFAKTVRLIQPIPKMWPTPSDADSGISSMGSSLASTARLK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *. :* . :*. :** * :* : :: : .. :: : . . : : *: . .. . * * . * . : .:: :.* ** . : . * : : : . :. .: . .:. . : . : : . . * ..* : ** : .: : . * : : : :** ** : * : :. *:* . : ::.. :.. :: . : . : : . . . : : . : : : . : : . .::: . .*. :: : ::**. : * * . *:*: * .: . .:: :: .: ** ***:* *:*. .*.: :: : * * :. : ** : *.: :. ", "identical_positions": 49, "similar_positions": 146, "identity": "5.1%" }, { "cls_id": "homologset.agr.MGI:1289168", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0R459-1", "uniprot_id": "M0R459_RAT", "id": "M0R459-1", "name": "", "aln": "MRPLVLLWGCLVLPGYEALTGPKEISGFEGDTVSLRCTYKKEMKVHRKYWCRQGGILLSRCGDTVYTNQD-QEVTRGKMSIRDSLQDLWVTVTMRDLTLKDSGKYWCGIDRLGRDESFEVKLIVFPGKRDSPVPTGTCCPSSPTPSFQPLTPTRRLQPKAKAWLTQLPELTSPGLHPTVVTTKQGKTRVKAPVFTEAAPAWSTGTSQVPSGISPHAGSSPHTATPARSAGTSQVPPGISPYAGRSPHTATSPHAGSSRPVIWPPLTTPKD-SRAVTSSVSKSSVSIPMVRIMAPVLVLLSLLLAAGLIAIGSHMLRRQRKKSWLATETQKNEKVYLETSLPGNGWTSEDSMIDLAVPPECLRNPN----PSAEKHNLSQS-AEEEAAPSLD-AEEDVVVAPPLHMSAEELAFSEFISV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q1ERP8-1", "uniprot_id": "CLM9_MOUSE", "id": "Q1ERP8-1", "name": "CMRF35-like molecule 9", "aln": "MRPLVLLWGCLVLPGYEALKGPKEISGFEGDTVSLRCTYVEKMKEHRKYWCRQGGILVSRCGDIVYANQD-QEVTRGRMSIRDSPQELSMTVIMRDLTLKDSGKYWCGIDRLGRDESFEVTLIVFPGKRDNAVPAGTCCPSSPTPSFQPLTPTRSLQPKAKAWQTQLPEPRS------------------------------------------------------------------------------------SRPVVWLPLTTPQD-SRAVASSVSKPSVSIPMVRMMAPVLILLSLLLAAGLIAFGSHMLR-WRKKAWLATETQKNEKVYLETSLPGNGWTTEDSTIDLAVTPECLRNLNPSAVPSPETQNLSQSTEEEEAARSLDDDKEDVMAPPPLQMSAEELAFSEFISV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6UXG3-1", "uniprot_id": "CLM9_HUMAN", "id": "Q6UXG3-1", "name": "CMRF35-like molecule 9", "aln": "MRLLVLLWGCLLLPGYEALEGPEEISGFEGDTVSLQCTYREELRDHRKYWCRKGGILFSRCSGTIYAEEEGQETMKGRVSIRDSRQELSLIVTLWNLTLQDAGEYWCGVEKRGPDESLLISLFVFPG---------PCCPPSPSPTFQPLATTR-LQPKAKAQQTQPPGLTSPGLYPAATTAKQGKTGAEAPPLPGTSQYG---------------------------------HERTSQYTGTSPHPATSPPAGSSRPPMQLDSTSAEDTSPALSSGSSKPRVSIPMVRILAPVLVLLSLLSAAGLIAFCSHLLL-WRKEAQQATETQRNEKFCLSR------LTAE----------------------------------EKEAPSQAP--EGDVISMPPLHTSEEELGFSKFVSA", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** ********:******* **:************:*** :::: *******:****.***.. :*:::: **. :*::***** *:* : * : :***:*:*:****::: * ***: :.*:**** .***.**:*:****:.** ******* ** * * *** : *:.:* * *::*. **. *******::****:***** ******: **:* **:: *****:***. *. *:* *:**. . : **: ***: * ***.**:*:*.", "identical_positions": 165, "similar_positions": 69, "identity": "39.47%" }, { "cls_id": "homologset.agr.MGI:1289171", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GDZ5-1", "uniprot_id": "A0A8I6GDZ5_RAT", "id": "A0A8I6GDZ5-1", "name": "tRNA N(3)-cytidine methyltransferase", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAA-------SLSEGVPETE---------DRKRPQ------------------FGNRFLSDPARVFHHNAWDNVKWSEEQAAAAERKVQENSSQLVCPEKQADYEVNAHKYWDDFYKVHENGFFKDRHWLFTEFPELAPS--HDHLVNLHLEKQKNEVSKPRSSEDGPG-LAAEQHKRPCTSHGCETRVPPVEEPVTQKLTHLEICADDFPGSSATYRILEVGCGVGNTVFPILQTNNNPDLFVYCCDFSATAIELVKTNSEYDPSRCFAFVHDLCDEDQSYP--MPKDSLDVIVLIFVLSAIVPDKMQKAISKLSRLLKPGGVMLLRDYGRYDMAQLRFKKGQCLSGNFYVRGDGTRVYFFTQDELDTLFTAAGLEKVQNVVDRRLQVNRGKQLTMYRVWIQCKYSKPLVPSASQHVPTPHTT---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BMK1-1", "uniprot_id": "METL2_MOUSE", "id": "Q8BMK1-1", "name": "tRNA N(3)-cytidine methyltransferase METTL2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAA-------SFPEGVPETE---------DGKRPQ------------------FGHRFLSDPARVFHHNAWDNVKWSEEQAAAAERKVQENSSPLVCPEKQVDYEVNAHKYWDDFYRIHENGFFKDRHWLFTEFPELAPS--HSHLTGVPLEKQRSDVC-----EDGPG-LTAEQHKCSCASPGCETQVPPLEEPVTQKLGHLEISGEEFPGSSATYRILEVGCGVGNTVFPILQTNNNPNLFVYCCDFSATAIELLKTNSQYDPSRCYAFVHDLCDEDQSYP--VPEDSLDVIVLIFVLSAIVPDKMQKAISKLSRLLKPGGVMLLRDYGRYDMAQLRFKKGQCLSGNFYVRGDGTRVYFFTQGELDTLFTAAGLEKVQNLVDRRLQVNRGKQLTMYRVWIQCKYSKPLALRSSQHVPIPHATESSSHSGLL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96IZ6-1", "uniprot_id": "MET2A_HUMAN", "id": "Q96IZ6-1", "name": "tRNA N(3)-cytidine methyltransferase METTL2A", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAG-------SYPEGAPAVL---------ADKRQQ------------------FGSRFLRDPARVFHHNAWDNVEWSEEQAAAAERKVQENSIQRVCQEKQVDYEINAHKYWNDFYKIHENGFFKDRHWLFTEFPELAPSQNQNHLKDWFLEN-KSEVPECRNNEDGPGLIMEEQHKCSSKSLEHKTQTLPVEENVTQKISDLEICADEFPGSSATYRILEVGCGVGNTVFPILQTNNDPGLFVYCCDFSSTAIELVQTNSEYDPSRCFAFVHDLCDEEKSYP--VPKGSLDIIILIFVLSAIVPDKMQKAINRLSRLLKPGGMMLLRDYGRYDMAQLRFKKGQCLSGNFYVRGDGTRVYFFTQEELDTLFTTAGLEKVQNLVDRRLQVNRGKQLTMYRVWIQCKYCKPLLSSTS------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6P1Q9-1", "uniprot_id": "MET2B_HUMAN", "id": "Q6P1Q9-1", "name": "tRNA N(3)-cytidine methyltransferase METTL2B", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAG-------SYPEGAPAIL---------ADKRQQ------------------FGSRFLSDPARVFHHNAWDNVEWSEEQAAAAERKVQENSIQRVCQEKQVDYEINAHKYWNDFYKIHENGFFKDRHWLFTEFPELAPSQNQNHLKDWFLEN-KSEVCECRNNEDGPGLIMEEQHKCSSKSLEHKTQTPPVEENVTQKISDLEICADEFPGSSATYRILEVGCGVGNTVFPILQTNNDPGLFVYCCDFSSTAIELVQTNSEYDPSRCFAFVHDLCDEEKSYP--VPKGSLDIIILIFVLSAVVPDKMQKAINRLSRLLKPGGMVLLRDYGRYDMAQLRFKKGQCLSGNFYVRGDGTRVYFFTQEELDTLFTTAGLEKVQNLVDRRLQVNRGKQLTMYRVWIQCKYCKPLLSSTS------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A8KBL7-1", "uniprot_id": "MET2A_DANRE", "id": "A8KBL7-1", "name": "tRNA N(3)-cytidine methyltransferase METTL2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAAPVVAADSPVIENMPETAGGATENSAEAQKRPQ------------------FGTRFLTDPRQVFQHNAWDNVEWSAEQEEAALKKVQENS-QPLPAEKQEEFDNRANEYWNDFYTIHENRFFKDRHWLFTEFPELAPQ--QKHLRG--AEEKES-----------------------------------LEHMLNGEDISLNPTHDEFPGASASYRILEVGCGVGNTVFPILKTNNDPGLFVYCCDFSSTAVDLVKSNPEYDPSRCHAFVHDMSDESGEYP--MPDHSLDVIVLIFVLSALHPEKMQKSINRLGRLLKPGGVLLLRDYGRYDMAQLRFKKGRCLSENFYVRGDGTRVYFFTQDELHDLFSSAGLEKLQNLVDRRLQVNRGKQLTMYRVWVQCKYRKVLAPT--------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q86BS6-1", "uniprot_id": "MET2_DROME", "id": "Q86BS6-1", "name": "tRNA N(3)-methylcytidine methyltransferase Mettl2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLTTSSSTMLGKYGWQILRRLASKSWEHTRQRKKPSG-----------------AGSRVLTDAREVFEFNAWDHVQWDEEQELAAKAAVAKNSTSKMEAEQKERFQTDAPKFWDSFYGIHDNRFFKDRHWLFTEFPELAPL--------------------------------------------------AADSAVLQ------------PRS-----IFELGCGVGNTILPLLQYSSEPQLKVFGCDFSARAIEILRSQRQFDEKRCEVFVMDATLDHWQVP--FEENSQDIIVMIFVLSAIEPKKMQRVLDNCYRYLRPGGLLLFRDYGRYDLAQLRFKSGKCMEDNFYVRGDGTMVYFFTEEELRGMMTQAGLQEEQLIVDRRLQVNRCRGLKMYRVWIQTKFRKPL-----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08641-1", "uniprot_id": "AB140_YEAST", "id": "Q08641-1", "name": "tRNA(Thr) (cytosine(32)-N(3))-methyltransferase", "aln": "MGVADLIKKFESISKEEGDATVDTNSSSKPLKSNDETKELHQQESTAVPQEVDVNEEFENEPETINSSRTAEKPLETNLPKPETNEEDEEEGSMSENKIYSKGENADINVNDFQEYKEMENTGAEVLASSVEESDAIQEGVAEETEGIATPKQKENEKNDESEEESANNASEPAEEYSQSEEDADIEQSNGKETENAENASQQANDGSTSTTTSKNKKKKNKKKNKKKRNGNVNTNANVDDSTKTGENDDTTGDTTSSTTSAIQEVNDLEVVDDSCLGIDQQHNREHLKALTQDVKEETLENIAHEGRGDNTGDQNAVEKSDFEKSDTEGSRIGRDLPFEFGKRNLTEESDVWDHNAWDNVEWGEEQVQQAEEKIKEQFKHPVPEFDKKLYNENPARYWDIFYKNNKENFFKDRKWLQIEFPILYAS---------------------------------------------------------------------TRKDAEPVTIFEIGCGAGNTFFPILKDNENENLRIIAADFAPRAVELVKNSEQFNPKYGHATVWDLANPDGNLPDGVEPHSVDIAVMIFVFSALAPNQWDQAMDNLHKILKPGGKIIFRDYGAYDLTQVRFKKNRILEENFYVRGDGTRVYFFSEEKLREIFTKKYFLENKIGTDRRLLVNRKRQLKMYRCWVQAVFDVPQ-----------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: . * * * : *:..****:*:*. ** * : :: : .: :: . .:*: ** :.: *****:** *** * . *:*:***.***.:*:*: ..: * : .**:. *:::::.. ::: . . * * . * . * *: ::***:**: *.: :: :.. : *:*** :::**** **::*:***..: :. ********* ****:: :* ::: : : : .**** *** : *.*** *:* : ", "identical_positions": 93, "similar_positions": 95, "identity": "12.92%" }, { "cls_id": "homologset.agr.MGI:1289172", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A1Y0-1", "uniprot_id": "D4A1Y0_RAT", "id": "D4A1Y0-1", "name": "SCY1-like protein 2", "aln": "MESMLNKLKSTVTKVTADVTSAVMGNPVTREFDVGRHIASGGNGLAWKIFNGTKKSTKQEVAVFVFDKKLIDKYQKFEKDQIIDSLKRGVQQLTRLRHPRLLTVQHPLEESRDCLAFCTEPVFASLANVLGNWENLPSSISPDIKDYKLYDVETKYGLLQVSEGLSFLHSSVKMVHGNVTPENIILNKSGAWKIMGFDFCVSSSNPSEQEPKFPCKEWDPNLPSLCLPNPEYLAPEYILSVSCETASDMYSLGAVMYAVFNKGRPIFEVNKQDIYKSFS-RQLDQLSRLGSS-SLTSIPEEVREHVKLLLNVTPTVRPD-ADQMTKIPFFDDVGAVTLQYFDTLFQRDNLQKSQFFKGLPKVLPKLPKRVIVQRILPCLTS--------EFVNPDMVPFVLPNVLLIAEECTKEEYIKLILPELGPVFKQQEPIQILLIFLQK-MDLLLTKTPPDEIKNSVLPMVYRALEAP-----SIQIQELCLNIIPTFANLIDYPSMKNALIPRIKNACLQTSSLAVRVNSLVCLGKILEY--LDKWFVLDDILPFLQQIPSKEPAVLMGILGIYKCTFTHKKLGITKEQLAGKVLPHLIPLSIENNLNLNQFSSFIAVIKEMLSRLESEHRTKLEQLHIMQEQQRSLDIGNQMS-TSEETKVTPSGTQQIDKVFNNIG-ADLLSGGESENREDGLQGKQKRGSLTLEEKQKLAKEQEQAQKLKSQQPLKPQVHTPIAPVKQTKDLTDTLMENMSSLTSLSVSTPKISASSTFTSVPSTGLSMMFSTPIDNTKRNLTNGLNANMGFQTSGFNMPVNPNQNFFSGTSTAGVTTMTLGAPPTMSNFSPLSIPPASVKQTQQRPPDMSALNNLFGPQKPKVSMNQLSQQ------KPNQWLNQFVP--PQGSPGMGSAAMGTQVNVMGQAAFGMQGNPFFNPQSFAQPPP-TTMTS-----SSSASNDLKDLFG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CFE4-1", "uniprot_id": "SCYL2_MOUSE", "id": "Q8CFE4-1", "name": "SCY1-like protein 2", "aln": "MESMLNKLKSTVTKVTADVTSAVMGNPVTREFDVGRHIASGGNGLAWKIFNGTKKSTKQEVAVFVFDKKLIDKYQKFEKDQIIDSLKRGVQQLTRLRHPRLLTVQHPLEESRDCLAFCTEPVFASLANVLGNWENLPSSISPDIKDYKLYDVETKYGLLQVSEGLSFLHSSVKMVHGNVTPENVILNKSGAWKIMGFDFCVSSSNPSEQEPKFPCKEWDPNLPSLCLPNPEYLAPEYILSVSCETASDMYSLGAVMYAVFNQGRPIFEVNKQDIYKSFS-RQLDQLSRLGSS-SLTSIPEEVREHVKLLLNVTPTVRPD-ADQMTKIPFFDDVGAVTLQYFDTLFQRDNLQKSQFFKGLPKVLPKLPKRVIVQRILPCLTS--------EFVNPDMVPFVLPNVLLIAEECTKEEYIKLILPELGPVFKQQEPIQILLIFLQK-MDLLLTKTPPDEIKNSVLPMVYRALEAP-----SIQIQELCLNIIPTFANLIDYPSMKNALIPRIKNACLQTSSLAVRVNSLVCLGKILEY--LDKWFVLDDILPFLQQIPSKEPAVLMGILGIYKCTFTHKKLGITKEQLAGKVLPHLIPLSIENNLNLNQFSSFIAVIKEMLSRLESEHRTKLEQLHVMQEQQRSLDIGNQMS-TSEETKVAHSGSQQIDKVFNNIG-ADLLSGSESENREDGMQGKQKRGSLTLEEKQKLAKEQEQAQKLKSQQPLKPQVHTPIAPIKQTKDLTDTLMENMSSLTSLSVSTPKISASSTFTPVPSTGLGMMFSTPIDNTKRNLTNGLNANMGFQTSGFSMPVNPNQNFFSGTGTAGVTTMSLGAPPTMSNFSPLTIPPASVKQPQQRPTDMSALNNLFGPQKPKVSMNQLSQQ------KPNQWLNQFAP--PQGSPVMGSAAMGTQGNVMGQAAFGMQGNPFFNPQNFAQPPP-TTMTS-----SSSASNDLKDLFG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6P3W7-1", "uniprot_id": "SCYL2_HUMAN", "id": "Q6P3W7-1", "name": "SCY1-like protein 2", "aln": "MESMLNKLKSTVTKVTADVTSAVMGNPVTREFDVGRHIASGGNGLAWKIFNGTKKSTKQEVAVFVFDKKLIDKYQKFEKDQIIDSLKRGVQQLTRLRHPRLLTVQHPLEESRDCLAFCTEPVFASLANVLGNWENLPSPISPDIKDYKLYDVETKYGLLQVSEGLSFLHSSVKMVHGNITPENIILNKSGAWKIMGFDFCVSSTNPSEQEPKFPCKEWDPNLPSLCLPNPEYLAPEYILSVSCETASDMYSLGTVMYAVFNKGKPIFEVNKQDIYKSFS-RQLDQLSRLGSS-SLTNIPEEVREHVKLLLNVTPTVRPD-ADQMTKIPFFDDVGAVTLQYFDTLFQRDNLQKSQFFKGLPKVLPKLPKRVIVQRILPCLTS--------EFVNPDMVPFVLPNVLLIAEECTKEEYVKLILPELGPVFKQQEPIQILLIFLQK-MDLLLTKTPPDEIKNSVLPMVYRALEAP-----SIQIQELCLNIIPTFANLIDYPSMKNALIPRIKNACLQTSSLAVRVNSLVCLGKILEY--LDKWFVLDDILPFLQQIPSKEPAVLMGILGIYKCTFTHKKLGITKEQLAGKVLPHLIPLSIENNLNLNQFNSFISVIKEMLNRLESEHKTKLEQLHIMQEQQKSLDIGNQMN-VSEEMKVTNIGNQQIDKVFNNIG-ADLLTGSESENKEDGLQNKHKRASLTLEEKQKLAKEQEQAQKLKSQQPLKPQVHTPVATVKQTKDLTDTLMDNMSSLTSLSVSTPKSSASSTFTSVPSMGIGMMFSTPTDNTKRNLTNGLNANMGFQTSGFNMPVNTNQNFYSSPSTVGVTKMTLGTPPTLPNFNALSVPPAGAKQTQQRPTDMSALNNLFGPQKPKVSMNQLSQQ------KPNQWLNQFVP--PQGSPTMGSSVMGTQMNVIGQSAFGMQGNPFFNPQNFAQPP--TTMTN-----SSSASNDLKDLFG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1L881-1", "uniprot_id": "Q1L881_DANRE", "id": "Q1L881-1", "name": "", "aln": "MESMLNKLKSTVTKVTADVTSAVMGNPVTREFEVGKHIASGGPGMSWRIYNGTKKSTKQEVAVFVFDKKVIDRYQKFEKDQIIDSLKKGIQQLTRLRHPRLLTVQHPLEESRDCLAFCTEPVFASLANVLGQWDNLPSPVPTDIKDYKLYDVETKYGLLQVSEGLSFLHSGVKMVHGNLCSENIILNKSGAWKIMGFDFSISSSNPSDAEPKYVCKEWDPNLPPLCLPNPEYVAPEYILSVSCDSASDMYSLGVLIHAVFNEGKPVFKVNKQDIFKSFS-RQLDQLSHLSPG-VLSQIPEEVRQHVKMLLSVTSNVRPD-ADQMTKIPFFDDVGAMTLQYFDSLFQRDNLQKSQFFKGLPKVLPKLPKRVVVYRILPALMS--------EFVNPDMVPFILPNVLLIAEECTKEEYVRLVLPDLTPVFKMQEPVQILLIFLQK-MDLLLTKTPPEDIKNSVLPMVYRAVEAP-----SVQIQELCLNIIPTFANLIEYPSMKNSLIPRIKSTCLQTSSLAVRVNSLVCLGKILEY--LDKWFVIDEILPFLQQIPSREPAVLMGILGIYKCTFTHKKLGIPKEHLAGKSLPHLVSLSIDNNLNLNQFNSFMAVIKDMLTRMEAEHKVKLEQLHIMQEQQRSLNITNPIN-QSEDTKSTPSPATQVRDIDDIFGGSSANAGVNGKENGSSTVSQPSRVSLTLEEKQRLAKEQEQAAKLRSQQPLAPQSIKSATTTPQAKDLTSSLLNNMTSLNNMSLNSGTRTMPMQGNTISSTFP--AAPTMGGMSTMSVSNGFNSPIGFQTGGMGMGMRAPTPALYG---------GMATTTSTPNFSALTQNHN--QNQPGKPPDMSALDSLFASNKPKVSLNQMAPKPTPGTNAPSPWINQFGSGQPPQSAPIQSNPMGMSG---VQGGFGMQANPFFNPQNFSQPAASSTMNTGMMKQSASVNNDLKDLFG", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VAR0-1", "uniprot_id": "Q9VAR0_DROME", "id": "Q9VAR0-1", "name": "Protein kinase domain-containing protein", "aln": "-MDMINKFYSSAVQTVSTLSGVLPGNNVTREYEVLEQVCTAGVGLMWKVYNGHKKSTKQEVSVFVFEKKSLERWSKDDRETMLETLRRGVQQLTKIRHPHVLTVQHPLEESRDSLAFATEPVFASLANVVG--DNVRS-------EKKLYDVEIRHGLLQLFDGLQFLHQDAKIVHRNISAETIVINKNRSWKLFGFDFCIANQPATDGTPHWPFREYTTSLHVLAQPSLEYTAPELALNSVNTPDSDLFSLGVLIFTIY-AGKPLKMFGSD--YSSFR-RYANDLNQRKYP-PMNAVPSELTESLKALLHPSANLRPK-LHELKQIAYFQDVGVKTLSYLDSLYQWDNLQKSKFYKGLPQIIPTLPHRVNLHSILPYLVK--------EFVNSPMIPFVLPNVLLIAEMSSQREYCDHILPHLKPIFKLTDPIQILLIFMQK-MDLLLKLTPAEEVKQSVLPLLYRSLECD-----MPQIQDLCLAVLPTFSTLIDYNAMKNSVLPRIKKLCLQSSNVSVKVNCLISIGKLLEN--LDKWLVLDEILPFLQQIQSREPAIIMGIIGIYKIAMTNTKLGITKDVMAHKCIPYLVPLSVENGLTIAQFNTIISLIKEMMGRVEQEQREKLQQLSTIQRDNKPKDASEILANELENSTLSPYGSINGNKIN-----DDMFSG--------------------FTVGQPKAAIGAAIAPAKAREQLKISHNTISAPPAARPDILSSMMQ--SNLTGLGTITVAAAPPPTTTQMPSNNGWHSANPLVMNHQLASPQASNNNS-FSLDDLDPFAGGRP--------------SVGAPKANNTNGAN-------MYTVQQP----TVNYIYPTGYSLNSIQQHQQQ------------QLLGK--PSQAPTLQP-----------------QTQPLLPTDNQNLNAL--------------SQQDILNFLN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53009-1", "uniprot_id": "SCY1_YEAST", "id": "P53009-1", "name": "Protein kinase-like protein SCY1", "aln": "--MMFWSSKTGITSKYSFSSSPTFTAEPWSIYTGRPKSSSSSSPSKVSIFMFDKKQFENYLLHYGIIKSKSGSRDKVLIQEAYEILRNQANNLAKLKHPNILTLIEPLEEHSKNFMFVTEFVTSSLETVFRETDDEEQN---FLQGHVKDNIVVQRGILQLVNALDFVHNRASFVHLNIQPRAIFINENSDWKISGLGYLVKIPPGTN-TSEYFLPQYDPRVPPFMHLQLNYTAPEIVFENTLTFKNDYFSLGLLIYFLYTGKDLFRSENSTSEYKLEYNKFESKISTMSWDNIFSKVPQKLRHCIPKLINRDIYSRYDNITLILDSEFFQDPLVKTLNFLDDLPTKNNEEKYVFLEGLVNLLPEFPPALLQKKFLPILLELLSQFCAEKVVSDKCVGKSLDLIIKIGSTLSQLSFQEKVYPVLLSDANFPVLLKKATICLIDNLDTLKQKVKRSDFLENILKPLFNYVLHDSESDITVVCQEKLLSQIPLALEVLDFPTVKQFLLPLLSNLFTKTTSLTVKNTCVTCFQIMIEHKSIDSYTCSETVLPLFKSMKTRDPRILSKLLKLFETVP---LIITDEIVLVDQVLPLMWNYSMASTLTKSQYSGYTKAINKMSS--------DIQKHHIAKLDDKVNDIGEDAFHKVIEPTIMKK-----------------------------------------EDPETVAAKNIEVAAMQPVKKKTGSSYG-ETLPQSKSILNSKPLNPKNALATRGFPTRILNSPPQTPSSRTGSKVMTKGGSNDASSTKVEEEFNEFQSFSSTGS-----------------------IRQTSAPSDVWMN---------STPSPTPTSASSTNLPPGFS-ISLQPNKRK---------------------------------------------DGSSDIPRSNVYGSLI------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: . : .. : :. : : .:.. :: **. :: : : : *. .* : : *:. ::*::::**.:**: .**** . : * ** * :** .*. :: . :: : *:**: :.*.*:*. ..:** *: .. :.:*:. **: *:.: : :: ..: :: . : : . :* *** :. .* :*** ::. :: . .. :. : ..:. :. :*.:: . : *: * . : . :*:* . **.::* * :* :* * :** :::* :* : :** * . :.*. : * :: *.. :: .: : * * . : :: * : . :* * . .:. :.:* ::. : *: * :* :::: ::*: ::* :.. :::.::*: ..: .: ::* :*.: : :**:::.: :::* :: :: ::: . : : :. : :* : *: . *. *:. *:.* .::: : ::: : : : . : * :. : . : : .. :: . * . : . : : * *. . : . : * : . . . *:: : : .. : .. ", "identical_positions": 94, "similar_positions": 272, "identity": "9.74%" }, { "cls_id": "homologset.agr.MGI:1289174", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A037-1", "uniprot_id": "D4A037_RAT", "id": "D4A037-1", "name": "", "aln": "MWSGLLPPGLNESDVESDSEDEITLENPEPSEHNSQEDGEAGSNKGPAVSDCPAGQPEMGTQTGADADAYEKCPSGIPLNMWNKFQELHKKNSEQKNSTPRFRQKKRKRSKKGKSKSEKESSSEQSSSETQWKELTQYFGANDRFEPPVKQKKVEKSGLEKSIDQAVEEWDVEKAEELSNQLATRELGVKIAKAIACHKFVKAKKEAENSQAARKKKKLAWGFEAKKRWETKSNMGYM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C6C7-1", "uniprot_id": "F204A_MOUSE", "id": "Q8C6C7-1", "name": "Protein FAM204A", "aln": "MWSGLLPPGLNESDVESDSEDEIKLENPEPSEHNLQEDGKTGSSTKPAVSDFPTGQPE--TETEADADAYEKCPSGIPLNIWNKFQELHKKNSEQKNSTPRFRQKKRKRSKKGKLKNEKESHSEQSSNETQWEELTQYFGANDRFEPPVKQKKVEKSGLEKRIDQAVEEWDVEKAEELSNQLATRELGVKIAKAIACHKFVKAKKEAENSQAARKKKKLAWGFEAKKRWETKSNMGYM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H8W3-1", "uniprot_id": "F204A_HUMAN", "id": "Q9H8W3-1", "name": "Protein FAM204A", "aln": "MWSGLLPPGLNESDAESNSEDEATLEN---SGLNLQEDKEDESIRKTEIIDFSTDEPK--TETESNVNAYEECPSGIPIDMWNKFQELHKKHSEQKSTTSRFRGKRRKRSRKDKLKNEKELHSEPSSNETQWKELTQYFGVNDRFDPPVKRKKVEKSGLEKRIDQAVEEWNIEKAEELSNQLATRELGVKIAKAVACHNFVKAKKEVENSQAARKKKKLAWGFEAKKRWETKSNMGYM", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**************.**:**** .*** * * *** : * . : * .:.:*: *:* ::.:***:******:::**********:****.:*.*** *:****:*.* *.*** ** **.****:*******.****:****:********** ********::**********************:***:*******.*******************************", "identical_positions": 175, "similar_positions": 38, "identity": "73.53%" }, { "cls_id": "homologset.agr.MGI:1289184", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q91WC0-1", "uniprot_id": "SETD3_MOUSE", "id": "Q91WC0-1", "name": "Actin-histidine N-methyltransferase", "aln": "MGKKSR-------VKTQKSGTGATATVS-----------------------PKEILNLTSELLQKCSSPAPSPGKEWEEYTQIRALVEKIRKKQKGLSVTFDGKRED---------YFPDLMKWASENGASVEGFEMVNFKEEG------FGLRATRDIKAEELFLWVPRKLLMTVESAKNSVLGPLYSQDRILQAMGNIALAFHLLCERAS-PNSFWQP-YIQTLPSEYDTPLYFEEEEVRCLQSTQAIHDVFSQYKNTARQYAYFYKVIQTHPHANK-----------LPLKESFTYEDYRWAVSSVMTRQNQIPTE-----DGSRVTLALIPLWDMCNHTNGLITTGYNLEDDRCECVALQDFQAGDQIYIFYGTRSNAEFVIHSGFFFDNNSHDRVKIKLGVSKSDR-----------------------------LYAMKAEVLARAGIPTSSVFALHSTEPPISAQLLAFLRVFCMTEEELKEHLLGDSAIDRIFTLGNA------EFPVSWDNEVKLWTFLEDRASLLLKTYKTTIEEDKIVLKNPDLSVRATMAIKLRLGEKEILEKAVKSAAVNREYYRKHMEERAPLPRYEESDLGLLEGGVGDSRLP---LVLRKLEEEAG--VQESLSLTETVSKVKAAENGLVN--GENLIPNGTRSENESLSPEESENVTG--EESSGSMAKVKERL----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3V6U9-1", "uniprot_id": "SETD3_RAT", "id": "G3V6U9-1", "name": "Actin-histidine N-methyltransferase", "aln": "MGKKSR-------VKTQKSGTGATATVS-----------------------PKEILNLTSELLQKCSSPAPGPGKEWEEYTQIRALVEKIRKKQKGLSVTFDGKRED---------YFPDLMKWASENGASVEGFEMVNFKEEG------FGLRATRDIKAEELFLWVPRKLLMTVESAKNSILGPLYSQDRILQAMGNIALAFHLLCERAS-PNSFWQP-YIQTLPSEYDTPLYFEEEEVRCLQSTQAIHDVFSQYKNTARQYAYFYKVIQTHPHANK-----------LPLKDSFTYEDYRWAVSSVMTRQNQIPTE-----DGSRVTLALIPLWDMCNHTNGLITTGYNLEDDRCECVALQDFQAGDQIYIFYGTRSNAEFVIHSGFFFDNNSHDRVKIKLGVSKSDR-----------------------------LYAMKAEVLARAGIPTSSVFALHFTEPPISAQLLAFLRVFCMTEEELKEHLLGDSAIDRIFTLGNS------EFPVSWDNEVKLWTFLEDRASLLLKTYKTTIEEDKTVLKNPDLSVRATMAIKLRLGEKEILEKAVKSAAMNREYYRKHMEERAPLPRYEESDLGLLEGGVGDSRLP---LVLRKLEEEAG--VQESLSLTETVSKVKAAENGLVN--GESLIPNGTRSENESLSPEESENTTGDTEESSGSMDAVKERL----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q86TU7-1", "uniprot_id": "SETD3_HUMAN", "id": "Q86TU7-1", "name": "Actin-histidine N-methyltransferase", "aln": "MGKKSR-------VKTQKSGTGATATVS-----------------------PKEILNLTSELLQKCSSPAPGPGKEWEEYVQIRTLVEKIRKKQKGLSVTFDGKRED---------YFPDLMKWASENGASVEGFEMVNFKEEG------FGLRATRDIKAEELFLWVPRKLLMTVESAKNSVLGPLYSQDRILQAMGNIALAFHLLCERAS-PNSFWQP-YIQTLPSEYDTPLYFEEDEVRYLQSTQAIHDVFSQYKNTARQYAYFYKVIQTHPHANK-----------LPLKDSFTYEDYRWAVSSVMTRQNQIPTE-----DGSRVTLALIPLWDMCNHTNGLITTGYNLEDDRCECVALQDFRAGEQIYIFYGTRSNAEFVIHSGFFFDNNSHDRVKIKLGVSKSDR-----------------------------LYAMKAEVLARAGIPTSSVFALHFTEPPISAQLLAFLRVFCMTEEELKEHLLGDSAIDRIFTLGNS------EFPVSWDNEVKLWTFLEDRASLLLKTYKTTIEEDKSVLKNHDLSVRAKMAIKLRLGEKEILEKAVKSAAVNREYYRQQMEEKAPLPKYEESNLGLLESSVGDSRLP---LVLRNLEEEAG--VQDALNIREAISKAKATENGLVN--GENSIPNGTRSENESLNQESKRAVEDAKGSSSDSTAGVKE------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7SXS7-1", "uniprot_id": "SETD3_DANRE", "id": "Q7SXS7-1", "name": "Actin-histidine N-methyltransferase", "aln": "MGKKSR-------VKTQKSGTGATAAVS-----------------------PKEMMNLISELLQKCSSAAPSPGKEWEEYVQIRALVEKIRKKQKGMSVSFEGIRED---------FFSELMAWAAECRASCDGFEISNFADEG------YGLKATKDIKAEELFLWIPRKMLMTVESAKNSVLGPLYSQDRILQAMGNVTLALHLLCERAN-PSSPWLP-YIKTLPSEYDTPLYFEEEEVRHLLATQAIQDVLSQYKNTARQYAYFYKVIHTHPNASK-----------LPLKDAFTFDDYRWAVSSVMTRQNQIPTA-----DGSRVTLALIPLWDMCNHTNGLITTGYNLEDDRCECVALKDYKEGEQIYIFYGTRSNAEFVIHNGFFFEDNAHDRVKIKLGVSKGER-----------------------------LYAMKAEVLARAGIPASSIFALHCSEPPISAQLLAFLRVFCMTEEELRDYLVGDHAINKIFTLGNT------EFPVSWENEIKLWTFLETRAALLLKTYKTASEEDRSMLEKPDLSLHSRIAIKLRLAEKEILEHAVSCGRAKRLHFQKQLDEGAPLPLYEESDIALLEN--ADAKLP---IILRKLEEEEEEHVEEMNQLTPDAVCMNSSKIPVLN--GQCKDLNGTQ-EDPPGGGAVVKEIEKHDPSAKRTEGEPKDAGK---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W3U1-1", "uniprot_id": "SETD3_DROME", "id": "Q9W3U1-1", "name": "Actin-histidine N-methyltransferase", "aln": "MGKNTKRNKKTKQQQQQPQQNGVTASASGTAVEDFEDQQAASSLPSLNGKKRSQLNKLVEELLDLVEKQPANPNEEWKQYGQLQELLKQIMILEEPLSQAVCPQISDSPDDQTRLAKVEAFSAWAKDGGVHSEGLEIAIFPGYQ------LGLRATRPLAKDELVLSVPRKLILSEENNSDCRLFGKMTQATHLN------LAYDLVIEKIRGEFSEWRP-YIDVLPAKYNTVLYFTTKQMELLRGTAAAALAMRQCRVIAKQYAFLYKYAHTMTEPSTGNRSHPGERGLFFTQHGLCYKLYRWAVSTVMTRQNLVPSEKQESEDGPKLISALIPYWDMANHRPGKITSFYATVSRQLECTAQEAVNTGEQFFIYYGDRSNTDLLVHNGFVDPNNTKDYVNIRVGLSLTDA-----------------------------LAAKRASILDKLNIRHTAELRVLPAPDFISKELLAFVRVFKMSAEQLDHWCS---DLDRAGDLLHI------DCALETDHETRTWQFLEDRLKLLLAVFNKEMHEADEVK---ELELKDGQEIELMLFLYRRLERSILAGALQYAQEHRKV------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38732-1", "uniprot_id": "EFM1_YEAST", "id": "P38732-1", "name": "Protein-lysine N-methyltransferase EFM1", "aln": "-------------MITQTELDNCLQWAQ-------------------------NNGAFIDPKISFRITEDAGVSAFVNEKFSPKPDQALIRVPETLLITSQQALSEFS----------QAANERSLLNSVTQLYLSKLKFGTDA------VHLKSFYKPYLDVLPLHLPQPYFWSTDEVMN--LHGTDVYLTMRDTLNKLVKEWRMLFQALSIEHSSQDKQFLSLFQENKDSAVVPLEQFCAHINGCKLEDSEWNSFVAYLWSYCIFNSRAFPRVILGR-----------AGTDRTNLNEGFLYPIVDLLNHKNDVPVR-----------------WEMNEQ------------NELCFMSQTTTFSAQDELFNNYGNISNEKCLLNYGFWDSSNKFDFSRLTLKLPSTLVSGLPV------------------------DFNKSGNFVTDDGETTILQFSLKISEPLPPVLLALFAYLSKLKSEETPTVRSVLEGIDQLTSVVSQRLLFYKNFKIKTSSTQKLRPHVIKLIKLYYQDNKKILNATTEKLSVLQKKIYSNNKEFSLSFKTIFKNDKIFANSLLLVFGAINYEDLITKDCLNDALLLWIVKLINDKSNNQGGFIKQTFKEVSDSIVIEKEDVMEFLPFYKKYFPNLSERIPEIYSVGDWGIRQFIVADTAIDRLVWIRKSNKEPIFLMKKAYDLQI", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q08961-1", "uniprot_id": "RKM1_YEAST", "id": "Q08961-1", "name": "Ribosomal lysine N-methyltransferase 1", "aln": "--------------MSSDALKALLQWGA-------------------------SFGVIVPEELKFLYTDLKGIICVCEKDIDNPS----IKIPPEIVISRNLPMKFFG-----------LSESTKNINGWLKLFFAKIKFDRDNDTIVDNVRVNDKFKPYLDALPSRLNSPLVWNPSELKR--LSSTNIGNSIHEKFEGIFKEWFELVSSSDMFDLERVADDVQTFHNLDELTYEALYEKILKITELQR-PTIWYSFPAFLWSHLIFISRAFPEYVLNR---------------NCPDNSIVLLPIVDLLNHDYRSKVK-----------------WYPENG--------------WFCYEKIGTASQSRELSNNYGGKGNEELLSGYGFVLEDNIFDSVALKVKLPLDVVSTILETEPSLKLPLLSDYTTYAFENKDCVQQEKKATRSATDYINGVTYFINIQNEQCLEPLLDLFTYLSKAEEEDLHDLRARLQGIQMLRNALQSKLN-SITGPPATDDSYAIDPYRVYCADVYTKGQKQILKEALTRLKKLEKTMLSENKHQLLTMSKILKNDPAFAETELPSLFSNEDGEEVIFESTYDLLILWILLKTKKNSYP----TKYEWVGQQYTNFKQTAYISDDAKAFHTAYFEKQD-------DVDLAEVDHAIQFVVDNSFTRTSSTTEETILVRK-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : :. . . :: . * : : * :. : * : . . .. * : : . :. : : . : . .: : . . . . .: ::.:. * : :: ** .* . : ** .* * : : :. . : * * : *: :: . . : : . : : : . . ", "identical_positions": 15, "similar_positions": 71, "identity": "2.13%" }, { "cls_id": "homologset.agr.MGI:1289192", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CQ24-1", "uniprot_id": "FBX36_MOUSE", "id": "Q9CQ24-1", "name": "F-box only protein 36", "aln": "-MASWLPETLFEIVGQGPAPSKDYYQLLITR----------TQIIFRWWKISLRSEYRSAKPGETKESHEDFLDNSHLQVQVAVVFGTKILDYVFNLCEGKFDYLERLSDRLLLKIICYLDLEDIASLSQTSSKFEKLCKSDLLWEQIVQSTCDTITPDMRALAKNMGWRQMFLTNNIQLQRQTRKKKQRQENQAEKLA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NEA4-1", "uniprot_id": "FBX36_HUMAN", "id": "Q8NEA4-1", "name": "F-box only protein 36", "aln": "-MASWLPETLFETVGQGPPPSKDYYQLLVTR----------SQVIFRWWKISLRSEYRSTKPGEAKETHEDFLENSHLQGQTALIFGARILDYVINLCKGKFDFLERLSDDLLLTIISYLDLEDIARLCQTSHRFAKLCMSDKLWEQIVQSTCDTITPDVRALAEDTGWRQLFFTNKLQLQRQLRKRKQKYGNLREKQP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6ARV1-1", "uniprot_id": "A0A8I6ARV1_RAT", "id": "A0A8I6ARV1-1", "name": "", "aln": "PKKNRRPCLRAASPQRGKEGKKDSAKCPKEKPAGGERDGLSSRIIFRWWKISLRSEYRSAKPGETKETHEDFLDNSHLQVQVAVVFGAKILDYVFNLCEGKFDYLERLSDKLLLKIMNYLDLEDIARLSQTSSRFEKLCKSDSLWEQIVQSTYDTITPDMRALANDVGWRQMFFTNKIQLQRQIRKKKQRQGSETTKPT", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * :* .** : : :::***************:****:**:*****:***** *.*::**::*****:***:****:****** ***.*: ******** *.*** :* *** ** ********* ******:****:: ****:*:**::***** **:**: . * .", "identical_positions": 115, "similar_positions": 35, "identity": "57.79%" }, { "cls_id": "homologset.agr.MGI:1289196", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AKP6-1", "uniprot_id": "A0A8I6AKP6_RAT", "id": "A0A8I6AKP6-1", "name": "E3 ubiquitin-protein ligase RNF213", "aln": "-MGCPQCGHVSSEKAAKFCSQCGQKLSPAATEQ-DLKNNNALVEASTTEGKTEPGEVLREEVVLLSSTDSGKELQTEQGEVLREEVVLLSSTDSGKELQNPEESESDASWTTHVSKKEKRRRRRQGTISSS----EAASMSSGLWSLDLP----------SGPGSHNSALPQNQAQQGGTANQPGHSLDTVKMPVEKDGSACVEGSG-SSLRGPVAEGP-----EDAQRNPAASDYVEVKDLKTSNPSVDKG----------------PKMTDASQKASLPESKGEQP---------------GHGEKVPPIDTAANPVKRAR--KETRDDVQKQKPSPVSLATSK-DRDQKAELESKLATPVRKSDESRNTQ--PEDQKKPGGDRNYAAAAKNKNQ---QAAALEATKS-------THDPGDRVTVCFHAIVSRDFGFNPDKHRAYVRGGEGLGQKGWT-DACEMYYTQDLHDLGSLIEGKMDIPRQSLDKP-IPYKYVIHHGSSSKDSVEYEFIYEQPQKKGEHVNRCLQVDSTLLSS-GDWHQYDDIIWMRSPG-LLQQAKNYITDGTRKNLVRGKKQAAVIMLDRIFSVLQSWSAINLQTFMTQFRQFYSVVRVPMIHDGHARKWSSLQYEEREVRLNLWEHVKKLMMPFLEGKSGESLPADCPVRSKQILGLSILCMVEAADFTVPKKDLDSLCYLLIPSADSPE---ALHRDLSPVLSIRQRWHAYLITLCFRCIEVGCDRWLGILPLLHYCMQQSPPRKNSKSQT----EDVWAGLEGISFSEFRDKAS----ARSQALQLMQNRMALLHVDEYLFRSWFSLVPLESLSSYLENSEEYLSHMPTRVLDCFQGISYRLRGLGKISKQNIE----DVKKVFKILMYLVDMYQDRIFEESLPQIYLTECADLHETVCSITADRQFYQTPALSAELVCAVLQLSPPEHTEEGLVAKSYEDLVRTTFQEALNTTRKWLRTVFKSPMLSRNFAAVQLS---YPDEMAVWRRLVGINFPEK---YGWKGPLLGDMEGRLKQESPRLQISFFCSSHCCDEGP--HDSVARSIEKCVIEAVSSVCQSQTSVLEGLSCQDLQK---FGTLLSAVITKSWP-VHNGELVSDVDEIFKYLLKWPDVRQLFKLCGTNENITNHITKEGRRLMVTAESVFQKVAGELENGTIVVGQLELILKYKSQFLGIWDINSQRLQFQ-EKVYDMKGLLDRRKDDLFFLKREKRYVESLLTQLGRVKHFVQVELG----NIERIHSQDLSNKKLN---EAVIK-PPNSSFSNRKTHYYLSPDILEMASKLDSLKDSHVFQDFWHETAELLSNDTLDQDRRELK-----------LSLPDVVDHLYYPCYEKFYKLYMNLRSGEITFADVDVIFR--DFKDKYDELNVDLKFMCTLDPQDRKGWISQRVRQIKEYHTLYQAVSSAKVIVQVRRALGVTGDFSVLNPLLNFADDFEDFRNEKLNQISPQFIKAKELLQDISELRHRCLEELALQTELVHWLHEALKDINELKVFVDLASISAGENDIDVDRVACFHDAVQGYASLLYKLGANTDFNEFMNHLQELWRALDNDQHLPDKLKDSARNLEWLKTVKESHGSVELSSLSLATAINSRGIYIIQAPKDG-QKVSPDTVLHLLLPDDHGYQEAFRKYSTEELKELLNKLMLMSGRKDHSSNVEVETFSEVFSNMQRLVHVFINLHCAGNMLFRTWTAKVYCCP--GGGISMDFGS-KLLNQLTESGDVIQLLGALCRQMEDFLHEWKTVVAQKRATHFYLNLYTAEQLVYLSSELRK-----PRPSEAALMMLSFIKGKCTVQELIQATSACENKAAR-------------HCLQEAMRKLP------------QQLLSESTLMGKLRVIMTQSLECMSAFLPSCLDLDTLGRCLAHLARLGGS------------PVERPLPKGLQVGQPNLILCGHSEVLSAALAIYMQDPMQPLPTFDEVLLCTPGTTIEEVELFLRRCLT-LDSQEHKVYSLLFADQLSYEVGCQAEELFQSLSTQVHREDYQLVILCDAAREHCYIPSTFSQHKVPLVPQAPLPDIQAYLENHYQVPKQIQSAATVFRDGLCVGIVTSERAGVGKSLYVNTLHKKLKTKLQDETVPLKIIRLTEPHIDENHVLSALLPFLEKNYQKTPVIFHIDVSTSVQTGIPVFLFKLLILQYLMDINGKMWRRNPCHLYVVEIPQAHSVRPKRSS-KLNARAPLFKFLDIFPKVTCRPPKEVINMELTPKRS-----HIEPGMDPAEFCSEAFQRPYQYLRRFHQGQNLDAFRYEKDSVEGSPEECLQHFLIYCGLTNPSWSELRNFAWFLNCQLKDCEASVFCNSAFTGDTLRGFKNFVVTFMVLMARDFATPTLQTSDQSPGKHSATIDGVAEEDLAPFSLRKRWESEPHPYVFFNGDRMTMTFIGFHLKTNSNGYVDAINPSSGNIIKKDVMTKELFDGLKLQRVPFNINFDSLPRHEKLERLCLALGIEWPS-----DPDETYELTTDNMLKILAIEMRFRCGIPVIIMGETGCGKTRLIKFLSDLRRGSIEAETMKLVKVHGGTTPSMIYSRVKDAERTAFFNKAQHNLETILFFDEANTTDAVSCIKEVLCDRTVGGEHLNEDSGLHVIAACNPYRKHSQEMIHRLESAGLGYRVGAEETADRLGSIPLRQLVYRVHALPPSLIPLVWDFGQLNDSAERLYIQQIVQRLVDSVTVDQRETFVIANVLSASQEFMRKRENECGFVSLRDVERCVKVFQWFHDHSNMLLNKLADFLREC------CDSTPAFERDPVLWSLVMAIGVCYHASLEEKAPYRAAIARCLPKPYNSPKVILNEITHVQDLFLRDAPIRSNIARNLALKENVFMMVICIELKIPLFLVGKPGSSKSLAKIIVADAMQGQAASSDLFRCLKQVHLVSFQCSPHSTPQGIISTFKQCARFQQGKDLQQYVSVVVLDEVGLAEDSPKMPLKTLHPLLEDGCIE-DDPAPYKQVGFVGISNWALDPAKMNRGIFVSRGSPNEKELIESAEGICSSDRLVQDRIRGYFAPFAKAYETVCQKQDKEFFGLRDYYSLIKMVFAKAKASKKGLSPRDIAHAVLRNFSG-KDDIQALSIFTASLPETLYKEEVSTVELIKQNIHPDLQGSSRG-LDSADSRYLLVLTRNYVALQILQQTFFEG-----QQPEIIFGSSFPQDQEYTQICRNINRVKVCMETGKMVVLLNLQNLYESLYDALNQYYVYLGGQKYVDLGLGTHRVKCRVHTDFRLIVIEEKDVVYKQFPVPLINRLEKHYLDMNTVLQGWQKGIVQELQRWAHEFADVKADQFIAR--HKYSPADVFIGYHSHACASVVLQAVERQGCRNLTEELY---------------------------------------------------------------------------------RKVFEEAKFILLDCATPDAVVRLSGSSLGSFAANRLSQEYYYKQQHNSFVDFLLAHLRMDHHECWAVFTEITTFSRLLTSHDCDVLESELRGLAPKPIVLSLQQFDTEYSFLKDVRSCLRNPA-RRKILVIQTDFDDGIHSAQLVASAKYSAINEINKTQ-GTEDFVFVYFVTKLSRMGS------GTPYVGFHGGLWRSVHIDDLRRSTVMASDVTKLQNVTISQLFEPVDKPEP------EDDPEEEMETESSKS---GEVAEEQMEVEEEGSEEMKRACDLRGCDV---LDTTRLVRSCVQGAVGMLRDQSESCARNMRRVTILLDLLNEESTLNASFLRESKMRLHVLLNKQEENQVRSLKEWVTREAANQDALQEAGTFRHTLWKRVQDVVTPILASMISHIDRDGNLELLARPGSPAWAQDLWMFIYSDIKFLNIPLALNNTRSNSEMPFILVQSHMNLLKDACNAVPFSWRIRDYLEELWVQAQYI----TDTEGLSKKFVEIFQKTPLGLYLAQFPTAQQQELLQSYLKDFLLLTMKVSSREELMFLQMALRSCLSELQVASGTPEE----GLSLPWVHLAYQHFRTRLQNFSRILTIHPQVLSSLSQAAEKHNLAGCEMTLDAFAAMACAEILKGDILKPSPR--VWLQLVKNLSMPLELVCSEGYLQDSGSMTRAIIQEVRALWNRIFSIALFVEHVLLGTESQIPELSPLVTKYVSLLDKCLEEDSNLKTYRPFAAVMTTLCNCKDKASKKFCRFGIQPCSICQGDAQDPVCLPCDHVYCLPCIQTWLAP-GQMICPYCKTELPDKFSPTVSQ--NHRKAIEKHAQFRHMCNSFFVDLVSTMCFKDNIPPQKSVIDTLLSLLFVQKELLRDASQR-HREHTKSLSPFDDVVDKTPVIRSVVLKLLLKYSFHEVKGYIQNYLSQLEN-KAFLTEDKTELYLLFINCLEDSVYQKTSAGCRNHER-VLREEGHFLRTYSPGLRGSEPVRTASVEYLQEMARVRLCLDLAADFLSELQEGSE-LAEDKRCFLKHVEQFCTRVNNDWHRVYLVRKLSSQRGMEFVQSFSRQGHPYQWVFPREVLAQQ---KDHLSQLDRYLVHGDEYKAVRDAMAKAVLDCKTLDVGNALSTCRSPKDQQTAYLLLALYTEVTALYRSRNGSLHPDSKQLEAMNKFINESKILSAPKINRFAKSLVANTLP----LLQTRSANGSLRVTVTEMAIHVATILLCGQDKVLEPLRNLAFYPFKMVNAFLPTMPEDLLVHAKFWEGLTNVRWYTCPNGHPCSVGECGQPMEMSICPDCRVPIGGLNHKPSVGFDVIRNNEDRTQTGHVLGNPQSSGTAEASD-RGQSPVVFILTRLLTHLAMLVGAAQTPQALMNIIKPPVQDPQGFLEQHIQRDLEQLTKILGKSADETTHVVHLILSSLLKEQHQM----TLNFTEVLSTKGCRNNWEKHFG-TLLLRELKHLDKTLPAINARISQDERISSNPVTKIIYGDPATFLPHLPQKSVVHCSKIWSCRTKITVEYLQHIVEQKNGKETVPLLWHFLQKEAELRLVKFLPEILALQRDLVKQFQNVSEVEFSSIRSFIHSHHSDGLQKLLHDRITVFLSTWNALRRSLETNGEIKLPKDYCRSDLDLDAKFEVILPRRRGLGLCGTALVSYLISLHNKMVYVVQKLSNE-DNSYSVDTSEVADLHVISYDVERDLNPLILSNCQYQVQQGGETSQEFDLEKIQRQISSRFLQGKPRLTLKGIPTLVYRRDWNYEHLFMDIKNKMTQNPLPNSAINAISGQLQSYSDACEALSIVEVTLGFLSTAGGDPSMELNVYIQEVLQMCDQTS-QVLKALNRCQLRHIIALWQFLSAHKSERRLRLKKELFQEVDVKYKEDLSPRHARLLSTFLNEAGLDSFLLELHEMIVLKLRGA--QAESSFNPSWSLKDTLVSYMETKDSDVLTEVESQFPDEILMSSCVSVWKTAATRKWDRQSR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q555-1", "uniprot_id": "RN213_MOUSE", "id": "E9Q555-1", "name": "E3 ubiquitin-protein ligase RNF213", "aln": "-MECPQCGHVSSEKAPKFCSECGQKLPSAATVQGDLKNDNTLVVSSTPEGKT------------------------EQGAVLREEEVLLSSTDPGKELEKPEESDSNASWTTQMSKKEKRRRKRQGTISSS----EAP--SSGLWSLDMP----------PSPGSHNSALPQNQAQQGGAASQPGHPLDTENMPME-DGFVHTEGSG-SPLQGQAAER------TDAQSNLAPSDLAEVKDLNTSKPSVDKGLPLDGG-PALSAFKGHPKMTDASQKAPLPESKGETS---------------GQEKKVPPIDAAASPVKTAG--KETGEDVRKPKPSPVSPVASK-HGDQEAELKGKLATPVRKSNEGGNTQ--PEDQRKPGEGRNFAAAVKTQQAAAPQQAAAPEPTS-------AFNPRDTVTVYFHAIVSRHFGFNPEEHKVYVRGGEGLGQKGWT-DACEMYCTQDLHDLGSLVEGKMDIPRQSLDKP-IPYKYVIHRGGSSKDTVEYEFIYEQAQKKGEHVNRCLRVVSTSLGN-GDWHQYDDIICMRSTG-FFQQAKNRILDSTRKELLKGKKQAAVVMLDRIFSVLQPWSDINLQSFMTQFLQFYSVVREPMIHDGRARKWTSLQYEEKEVWTNLWEHVKKQMAPFLEGKSGESLPADCPVRSKLTLGLSILFMVEAAEFTVPKKDLDSLCYLLIPSAGSPE---ALHSDLSPVLRIRQRWRIYLTNLCLRCIDERCDRWLGILPLLHTCMQKSPPKKNSKSQP----EDTWAGLEGISFSEFRDKAP----TRSQPLQFMQSKMALLRVDEYLFRSWLSVVPLESLSSYLENSIDYLSDVPVRVLDCLQGISYRLPGLRKISNQNMKK---DVENVFKMLMHLVDIYQHRIFGENLLQIYLTECLTLHETVCNITANHQFFEIPALSAELICKLLELSPPGHTDEGLPEKSYEDLVTSTLQEALATTRNWLRSLFKSRMLSISSAYVRLT---YSEEMAVWRRLVEIGFPEK---HGWKGSLLGDMEGRLKQEPPRLQISFFCSSQCRDGGL--HDSVSRSFEKCVIEAVSSACQSQTSVLEGLSCQDLQK---FGTLLSAVITKSWP-VHNGEPVFDVDEIFKYLLKWPDVRQLFELCGTNEKIIDNITEEGRQLMATAESVFQKVAGELENGTIVVGQLELILEHQSQFLDIWNLNRRRLPSQ-EKACDVRSLLKRRRDDLLFLKQEKRYVESLLRQLGRVKHLVQVDFG----NIEIIHSQDLSNKKLN---EAVIK-LPNSSSYKRETHYCLSPDIREMASKLDSLKDSHIFQDFWQETAESLN--TLDKDPRELK-----------VSLPEVLEYLYNPCYDNFYTLYENLKSGKITFAEVDAIFK--DFVDKYDELKNDLKFMCTMNPQDQKGWISERVGQIKEYHTLHQAVSSAKVILQVRRALGVTGDFSVLNPLLNFADSFEDFGNEKLDQISPQFIKAKQLLQDISEPRQRCLEELARQTELVAWLHKALEDINELKVFVDLASISAGENDIDVDRVACFHDAVQGYASLLYKMDERTNFSDFMNHLQELWRALDNDQHLPDKLKDSARNLEWLKTVKESHGSVELSSLSLATAINSRGVYVIEAPKDG-QKISPDTVLRLLLPDGHGYPEALRTYSTEELKELLNKLMLMSGKKDHNSNTEVEKFSEVFSNMQRLVHVFIKLHCAGNMLFRTWTAKVYCCP--DGGIFMNFGL-ELLSQLTEKGDVIQLLGALCRQMEDFLDNWKTVVAQKRAEHFYLNFYTAEQLVYLSSELRK-----PRPSEAALMMLSFIKGKCTVQDLVQATSACESKADR-------------YCLREVMKKLP------------QQLLSEPSLMGKLQVIMMQSLVYMSAFLPHCLDLDALGRCLAHLATMGGT------------PVERPLPKGLQAGQPNLILCGHSEVLPAALAIYMQAPRQPLPTFDEVLLCTPATTIEEVELLLRRCLT-SGSQGHKVYSLLFADQLSYEVGCQAEEFFQSLCTRAHREDYQLVILCDAAREHCYIPSTFSQYKVPLVPQAPLPNIQAYLQSHYQVPKRLLSAATVFRDGLCVGIVTSERAGVGKSLYVNTLHTKLKAKLRDETVPLKIIRLTEPHLDENQVLSALLPFLKEKYQKMPVIFHIDISTSVQTGIPIFLFKLLILQYLMDINGKIWRRSPGHLYLVEIPQGLSVQPKRSS-KLNARAPLFKFLDLFPKVTCRPPKEVIDMELTPERS-----HTDPAMDPVEFCSEAFQRPYQYLKRFHQQQNLDTFQYEKGSVEGSPEECLQHFLIYCGLINPSWSELRNFAWFLNCQLKDCEASIFCKSAFTGDTLRGFKNFVVTFMILMARDFATPTLHTSDQSPGRQSVTIGEVVEEDLAPFSLRKRWESEPHPYVFFNGDHMTMTFIGFHLETNNNGYVDAINPSNGKVIKKDVMTKELFDGLRLQRVPFNIDFDNLPRYEKLERLCLALGIEWPI-----DPDETYELTTDNMLKILAIEMRFRCGIPVIIMGETGCGKTRLIKFLSDLKRGSVEAETMKLVKVHGGTTPSMIYSKVKEAERTAFSNKAQHKLDTILFFDEANTTEAVSCIKEILCDRTVDGEHLHEDSGLHIIAACNPYRKHSQEMILRLESAGLGYRVSAEETADRLGSIPLRQLVYRVHALPPSLIPLVWDFGQLNDSAEKLYIQQIVQRLVDSVSVNPSETCVIADVLSASQMFMRKRENECGFVSLRDVERCVKVFRWFHDHSDMLLKELDKFLHES------SDSTHTFERDPVLWSLVMAIGVCYHASLEEKASYRTAIARCFPKPYNSSRAILDEVTHVQDLFLRGAPIRTNIARNLALKENVFMMVICIELKIPLFLVGKPGSSKSLAKIIVADAMQGQAAFSELFRCLKQVHLVSFQCSPHSTPQGIISTFKQCARFQQGKDLGQYVSVVVLDEVGLAEDSPKMPLKTLHPLLEDGCIE-DDPAPYKKVGFVGISNWALDPAKMNRGIFVSRGSPNEKELIESAEGICSSDRLVQDKIRGYFAPFAKAYETVCQKQDKEFFGLRDYYSLIKMVFAKAKASKRGLSPQDITHAVLRNFSG-KDNIQALSIFTASLPEARYKEEVSTVELIKQNIYPGPQASSRG-LDGAESRYLLVLTRNYVALQILQQTFFEG-----QQPEIIFGSSFPQDQEYTQICRNINRVKICMETGKMVVLLNLQNLYESLYDALNQYYVYLGGQKYVDLGLGTHRVKCRVHTAFRLIVIEEKDVVYKQFPVPLINRLEKHYLDMNTVLQPWQKSIVQELQQWAHEFADVKADQFIAR--HKYSPADVFIGYHSDACASVVLQAVERQGCRDLTEELY---------------------------------------------------------------------------------RKVSEEARSILLDCATPDAVVRLSGSSLGSFTAKQLSQEYYYAQQHNSFVDFLQAHLRMTHHECRAVFTEITTFSRLLTGNDCDVLASELRGLASKPVVLSLQQYDTEYSFLKDVRSWLTNPG-KRKVLVIQADFDDGTRSAQLVASAKYTAINEINKTQ-GTKDFVFVYFVTKLSRMGS------GTSYVGFHGGLWRSVHIDDLRRSTIMASDVTKLQNVTISQLFKPEDKPE-----------QEEMEIETSQS---KELAEEQMEVED--SEEMKKASDPRSCDCSQFLDTTRLVQSCVQGAVGMLRDQNESCARNMRRVTILLDLLNEDNTRNASFLRESKMRLHVLLNKQEENQVRSLKEWVTREAANQDALQEAGTFRHTLWKRVQDVVTPILASMIAHIDRDGNLELLAQPDSPAWVQDLWMFIYSDIKFLNISLVLNNTRSNSEMSFILVQSHMNLLKDAYNAVPFSWRIRDYLEELWVQAQYI----TDTEGLSKKFVEIFQKTPLGVFLAQFPVAQQQKLLQSYLKDFLLLTMKVSSREELMFLQMALWSCLRELQEASGTPDETYKFPLSLPWVHLAFQHFRTRLQNFSRILTIHPQVLSSLSQAAEKHSLAGCEMTLDAFAAMACAEMLKGDLLKPSPK--AWLQLVKNLSTPLELVCSEGYLCDSGSMTRSVIQEVRALWNRIFSIALFVEHVLLGTESHIPELSPLVTTYVSLLDKCLEEDSNLKTCRPFVAVMTTLCDCKDKASKKFSRFGIQPCFICHGDAQDPVCLPCDHVYCLRCIQTWLIP-GQMMCPYCLTDLPDKFSPTVSQ--DHRKAIEKHAQFRHMCNSFFVDLVSTMCFKDNTPPEKSVIDTLLSLLFVQKELLRDASQK-HREHTKSLSPFDDVVDQTPVIRSVLLKLLLKYSFHEVKDYIQNYLTQLEK-KAFLTEDKTELYLLFISCLEDSVHQKTSAGCRNLEQ-VLREEGHFLRTYSPGLQGQEPVRIASVEYLQEVARVRLCLDLAADFLSELQEGSE-LAEDKRRFLKHVEEFCTRVNNDWHRVYLVRKLSSQRGMEFVQSFSKQGHPCQWVFPRKVIAQQ---KDHVSLMDRYLVHGNEYKAVRDATAKAVLECKTLDIGNALMACRSPKPQQTAYLLLALYTEVAALYRSPNGSLHPEAKQLEAVNKFIKESKILSDPNIRCFARSLVDNTLP----LLKIRSANSILKGTVTEMAVHVATILLCGHNQILKPLRNLAFYPVNMANAFLPTMPEDLLVHARTWRGLENVTWYTCPRGHPCSVGECGRPMQESTCLDCGLPVGGLNHTPHEGFSAIRNNEDRTQTGHVLGSPQSSGVAEVSD-RGQSPVVFILTRLLTHLAMLVGATHNPQALTVIIKPWVQDPQGFLQQHIQRDLEQLTKMLGRSADETIHVVHLILSSLLRVQSHG----VLNFNAELSTKGCRNNWEKHFE-TLLLRELKHLDKNLPAINALISQDERISSNPVTKIIYGDPATFLPHLPQKSIIHCSKIWSCRRKITVEYLQHIVEQKNGKETVPVLWHFLQKEAELRLVKFLPEILALQRDLVKQFQNVSRVEYSSIRGFIHSHSSDGLRKLLHDRITIFLSTWNALRRSLETNGEIKLPKDYCCSDLDLDAEFEVILPRRQGLGLCGTALVSYLISLHNNMVYTVQKFSNE-DNSYSVDISEVADLHVISYEVERDLNPLILSNCQYQVQQGGETSQEFDLEKIQRQISSRFLQGKPRLTLKGIPTLVYRRDWNYEHLFMDIKNKMAQSSLPNLAISTISGQLQSYSDACEALSIIEITLGFLSTAGGDPGMDLNVYIEEVLRMCDQTA-QVLKAFSRCQLRHIIALWQFLSAHKSEQRLRLNKELFREIDVQYKEELSTQHQRLLGTFLNEAGLDAFLLELHEMIVLKLKGP--RAANSFNPNWSLKDTLVSYMETKDSDILSEVESQFPEEILMSSCISVWKIAATRKWDRQSR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63HN8-3", "uniprot_id": "RN213_HUMAN", "id": "Q63HN8-3", "name": "E3 ubiquitin-protein ligase RNF213", "aln": "-MECPSCQHVSKEETPKFCSQCGERLPPAAPIADSENNNSTMASASEGEMEC--------------------------GQELKEEGGPCLFPGSDSWQENPEEPCSKASWTVQESKKKKRKKKKKGNKSASSELASLPLSPASPCHLTLL----------SNPWPQDTALPHSQAQQSGPTGQPSQPPGTATTPLEGDGLSAPTEVGDSPLQAQALGEAGVATGSEAQSSPQFQDHTEGEDQDASIPSGGRGLSQEGTGPPTSAGEGHSRTEDAAQELLLPESKGGSSEPGTELQTTEQQAGASASMAVDAVAEPANAVKGAG--KEMKEKTQRMKQPPATTPPFK-THCQEAETKTKDEMAAAEEKVGKNEQGEPEDLKKPEGKNRSAAAVKNEKEQKNQEADVQEVKAS------TLSPGGGVTVFFHAIISLHFPFNPDLHKVFIRGGEEFGESKWDSNICELHYTRDLGHDRVLVEGIVCISKKHLDKY-IPYKYVIYNG----ESFEYEFIYKHQQKKGEYVNRCLFIKSSLLGS-GDWHQYYDIVYMKPHG-RLQKVMNHITDGPRKDLVKGKQIAAALMLDSTFSILQTWDTINLNSFFTQFEQFCFVLQQPMIYEGQAQLWTDLQYREKEVKRYLWQHLKKHVVPLPDGKSTDFLPVDCPVRSKLKTGLIVLFVVEKIELLLEG-SLDWLCHLLTSDASSPD---EFHRDLSHILGIPQSWRLYLVNLCQRCMDTRTYTWLGALPVLHCCMELAPRHKDAWRQP----EDTWAALEGLSFSPFREQML----DTSSLLQFMREKQHLLSIDEPLFRSWFSLLPLSHLVMYMENFIEHLGRFPAHILDCLSGIYYRLPGLEQVLNTQDVQDVQNVQNILEMLLRLLDTYRDKIPEEALSPSYLTVCLKLHEAICSSTKLLKFYELPALSAEIVCRMIRLLS-LVDSAGQRDETGNNSVQTVFQGTLAATKRWLREVFTKNMLTS--SGASFT---YVKEIEVWRRLVEIQFPAE---HGWKESLLGDMEWRLTKEEPLSQITAYCNSCWDTKGL--EDSVAKTFEKCIIEAVSSACQSQTSILQGFSYSDLRK---FGIVLSAVITKSWP-RTADN----FNDILKHLLTLADVKHVFRLCGTDEKILANVTEDAKRLIAVADSVLTKVVGDLLSGTILVGQLELIIKHKNQFLDIWQLREKSLSPQ-DEQCAVEEALDWRREELLLLKKEKRCVDSLLKMCGNVKHLIQVDFG----VLAVRHSQDLSSKRLN---DTVTVRLSTSSNSQRATHYHLSSQVQEMAGKIDLLRDSHIFQLFWREAAEPLSEPKEDQEAAELLSEPEEESERHILELEEVYDYLYQPSYRKFIKLHQDLKSGEVTLAEIDVIFK--DFVNKYTDLDSELKIMCTVDHQDQRDWIKDRVEQIKEYHHLHQAVHAAKVILQVKESLGLNGDFSVLNTLLNFTDNFDDFRRETLDQINQELIQAKKLLQDISEARCKGLQALSLRKEFICWVREALGGINELKVFVDLASISAGENDIDVDRVACFHDAVQGYASLLFKLDPSVDFSAFMKHLKKLWKALDKDQYLPRKLCDSARNLEWLKTVNESHGSVERSSLTLATAINQRGIYVIQAPKGG-QKISPDTVLHLILPESPGSHEESREYSLEEVKELLNKLMLMSGKKDRN-NTEVERFSEVFCSVQRLSQAFIDLHSAGNMLFRTWIAMAYCSPKQGVSLQMDFGL-DLVTELKEGGDVTELLAALCRQMEHFLDSWKRFVTQKRMEHFYLNFYTAEQLVYLSTELRK-----QPPSDAALTMLSFIKSNCTLRDVLRASVGCGSEAAR-------------YRMRRVMEELP------------LMLLSEFSLVDKLRIIMEQSMRCLPAFLPDCLDLETLGHCLAHLAGMGGS------------PVERCLPRGLQVGQPNLVVCGHSEVLPAALAVYMQTPSQPLPTYDEVLLCTPATTFEEVALLLRRCLT-LGSLGHKVYSLLFADQLSYEVARQAEELFHNLCTQQHREDYQLVMVCDGDWEHCYLPSAFSQHKVFVTPQAPLEAIQAYLAGHYRVPKQTLSAAAVFNDRLCVGIVASERAGVGKSLYVKRLHDKMKMQLNVKNVPLKTIRLIDPQVDESRVLGALLPFLDAQYQKVPVLFHLDVTSSVQTGIWVFLFKLLILQYLMDINGKMWLRNPCHLYIVEILERRTSVPSRSSSALRTRVPQFSFLDIFPKVTCRPPKEVIDMELSALRS-----DTEPGMDLWEFCSETFQRPYQYLRRFNQNQDLDTFQYQEGSVEGTPEECLQHFLFHCGVINPSWSELRNFARFLNYQLRDCEASLFCNPSFIGDTLRGFKKFVVTFMIFMARDFATPSLHTSDQSPGKHMVTMDGVREEDLAPFSLRKRWESEPHPYVFFNDDHTTMTFIGFHLQPNINGSVDAISHLTGKVIKRDVMTRDLYQGLLLQRVPFNVDFDKLPRHKKLERLCLTLGIPQAT-----DPDKTYELTTDNMLKILAIEMRFRCGIPVIIMGETGCGKTRLIKFLSDLRRGGTNADTIKLVKVHGGTTADMIYSRVREAENVAFANKDQHQLDTILFFDEANTTEAISCIKEVLCDHMVDGQPLAEDSGLHIIAACNPYRKHSEEMICRLESAGLGYRVSMEETADRLGSIPLRQLVYRVHALPPSLIPLVWDFGQLSDVAEKLYIQQIVQRLVESISLDENGTRVITEVLCASQGFMRKTEDECSFVSLRDVERCVKVFRWFHEHSAMLLAQLNAFLSKS------SVSKNHTERDPVLWSLMLAIGVCYHASLEKKDSYRKAIARFFPKPYDDSRLLLDEITRAQDLFLDGVPLRKTIAKNLALKENVFMMVVCIELKIPLFLVGKPGSSKSLAKTIVADAMQGPAAYSDLFRSLKQVHLVSFQCSPHSTPQGIISTFRQCARFQQGKDLQQYVSVVVLDEVGLAEDSPKMPLKTLHPLLEDGCIE-DDPAPHKKVGFVGISNWALDPAKMNRGIFVSRGSPNETELIESAKGICSSDILVQDRVQGYFASFAKAYETVCKRQDKEFFGLRDYYSLIKMVFAAAKASNRKPSPQDIAQAVLRNFSG-KDDIQALDIFLANLPEAKCSEEVSPMQLIKQNIFGPSQKVPGGEQEDAESRYLLVLTKNYVALQILQQTFFEGD----QQPEIIFGSGFPKDQEYTQLCRNINRVKICMETGKMVLLLNLQNLYESLYDALNQYYVHLGGQKYVDLGLGTHRVKCRVHPNFRLIVIEEKDVVYKHFPIPLINRLEKHYLDINTVLEKWQKSIVEELCAWVEKFINVKAHHFQKR--HKYSPSDVFIGYHSDACASVVLQVIERQGPRALTEELH---------------------------------------------------------------------------------QKVSEEAKSILLNCATPDAVVRLSAYSLGGFAAEWLSQEYFHRQRHNSFADFLQAHLHTADLERHAIFTEITTFSRLLTSHDCEILESEVTGRAPKPTLLWLQQFDTEYSFLKEVRNCLTNTA-KCKILIFQTDFEDGIRSAQLIASAKYSVINEINKIR-ENEDRIFVYFITKLSRVGR------GTAYVGFHGGLWQSVHIDDLRRSTLMVSDVTRLQHVTISQLFAPGDLPELGLEHRAEDGHEEAMETEASTSGEVAEVAEEAMETES--SEKVGKETSELGGSDVSILDTTRLLRSCVQSAVGMLRDQNESCTRNMRRVVLLLGLLNEDDACHASFLRVSKMRLSVFLKKQEESQFHPL-EWLAREACNQDALQEAGTFRHTLWKRVQGAVTPLLASMISFIDRDGNLELLTRPDTPPWARDLWMFIFSDTMLLNIPLVMNNERHKGEMAYIVVQNHMNLSENASNNVPFSWKIKDYLEELWVQAQYI----TDAEGLPKKFVDIFQQTPLGRFLAQLHGEPQQELLQCYLKDFILLTMRVSTEEELKFLQMALWSCTRKLKAASEAPEE----EVSLPWVHLAYQRFRSRLQNFSRILTIYPQVLHSLMEARWNHELAGCEMTLDAFAAMACTEMLTRNTLKPSPQ--AWLQLVKNLSMPLELICSDEHMQGSGSLAQAVIREVRAQWSRIFSTALFVEHVLLGTESRVPELQGLVTEHVFLLDKCLRENSDVKTHGPFEAVMRTLCECKETASKTLSRFGIQPCSICLGDAKDPVCLPCDHVHCLRCLRAWFAS-EQMICPYCLTALPDEFSPAVSQ--AHREAIEKHARFRQMCNSFFVDLVSTICFKDNAPPEKEVIESLLSLLFVQKGRLRDAAQR-HCEHTKSLSPFNDVVDKTPVIRSVILKLLLKYSFHDVKDYIQEYLTLLKK-KAFITEDKTELYMLFINCLEDSILEKTSAYSRNDELNHLEEEGRFLKAYSPASRGREPANEASVEYLQEVARIRLCLDRAADFLSEPEGGPE-MAKEKQCYLQQVKQFCIRVENDWHRVYLVRKLSSQRGMEFVQGLSKPGRPHQWVFPKDVVKQQGLRQDHPGQMDRYLVYGDEYKALRDAVAKAVLECKPLGIKTALKACKTPQSQQSAYFLLTLFREVAILYRSHNASLHPTPEQCEAVSKFIGECKILSPPDISRFATSLVDNSVP----LLRAGPSDSNLDGTVTEMAIHAAAVLLCGQNELLEPLKNLAFSPATMAHAFLPTMPEDLLAQARRWKGLERVHWYTCPNGHPCSVGECGRPMEQSICIDCHAPIGGIDHKPRDGFHLVKDKADRTQTGHVLGNPQRR-DVVTCD-RGLPPVVFLLIRLLTHLALLLGASQSSQALINIIKPPVRDPKGFLQQHILKDLEQLAKMLGHSADETIGVVHLVLRRLLQEQHQLSSRRLLNFDTELSTKEMRNNWEKEIA-AVISPELEHLDKTLPTMNNLISQDKRISSNPVAKIIYGDPVTFLPHLPRKSVVHCSKIWSCRKRITVEYLQHIVEQKNGKERVPILWHFLQKEAELRLVKFLPEILALQRDLVKQFQNVQQVEYSSIRGFLSKHSSDGLRQLLHNRITVFLSTWNKLRRSLETNGEINLPKDYCSTDLDLDTEFEILLPRRRGLGLCATALVSYLIRLHNEIVYAVEKLSKE-NNSYSVDAAEVTELHVISYEVERDLTPLILSNCQYQVEEGRETVQEFDLEKIQRQIVSRFLQGKPRLSLKGIPTLVYRHDWNYEHLFMDIKNKMAQDSLPSSVISAISGQLQSYSDACEVLSVVEVTLGFLSTAGGDPNMQLNVYTQDILQMGDQTI-HVLKALNRCQLKHTIALWQFLSAHKSEQLLRLHKEPFGEISSRYKADLSPENAKLLSTFLNQTGLDAFLLELHEMIILKLKNPQTQTEERFRPQWSLRDTLVSYMQTKESEILPEMASQFPEEILLASCVSVWKTAAVLKWNREMR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IBK5-1", "uniprot_id": "R213A_DANRE", "id": "A0A0R4IBK5-1", "name": "E3 ubiquitin-protein ligase rnf213-alpha", "aln": "-MKCPKCSHEALEKAPKFCSECGHKLQSQSYETTQGTPHDKSQTPSIVPQIT--------------------------NAEMDETGSESKSLEIQNANVSPKRPNENTSPNPKKKKRKKRKKEKKKKSGVS---EGPSSLTSDLSDISLTDKEKKMDTDQSSDSDCSSCIVEDTPTPAEPSSHLSPPENETAGPAQLSASALTTGSSKDGEESIGTTQKPVS--ASASKAPLGVDQQTKEEKVKCKDEGQKSLSAKAQHTPNANVDQNANVQSDANIDKDSQNVEPQK--------------SSSVKTKPSKSTVADPKKTESEKQKSGERDNENSTQPVSSPKLKRNQTEESQKMVFGPNSAPKKNRGSSADSAMKVEKKPAGGKKDSSADQKSKESEDTESQCVTLPKRNTRSTQHISSSDRLTIYFHAVLSKDFKFNPEEDLIFIRAGGPIG--NWEENLVELSVSRDLKEHGFLVEGKFICRKIDAEAVSIPYKYVVYKQ--KKNKYDYEYIYKLDAEVP--TNRCLFIKSHLLNDEGEWHQYDDIICAQPAKNMFEWVKKTIWSDEKKNVLQGRKIAGTIMLETIFDLLRSWSKINLNNFFSQLRQFYEIYRNPFVFEKKQTKWYQLDYDEKDVRELLKNFMLMHVTPELQKDSNE---KSKFIQEPLKAGLIMLYVWKQYDLKLDYGTLSRLCTAVCLPNLPKDEFLSLWTDITESFSVINSFSDMVEALISKLKAENMPRWIIVIPLLHLLKGTSKPFEQVITKVNSKYEQSWAGLQGLRSNILSPGPQ----ERRAMLNLMKTYGHLVEVDRLLIRSWMYLMPLDDLVECG-------SIFPVELLDILQLFTMKCP--NNISFTSSES----TAEALAHIQSQLLQHRYSCPDVDYGIQCIQAACKLLEKICSLVRYFGHSQN-FTDIPVACMNLVASVSGFAQTKQEADTFAEKTLVLLNDTKQTVRAWMRQTFKGRLLNSHLFSSHLTGTSFSTETEVWNNIIAIDFVCKDFIKEWRDTFTTDFEGKYQQEDHLDQIEAYCSNIEKLKVS--QPYLVNSVEKCALQAVSTICQTKSEWKLFARFNKFRINWRFGNLVSTIILKSWPKDDKGTYFEEEEAVLKHLLGWAAAKNIFQLHGADEKLIDQLSDEAKEKFAMATSLFTNVLNQLVTGKIKMKLLNHILEKKSVFLELLTLDCFSEEEQYKDIDAMKALIQTRQEEVKAIYHERALAGALIAMCHNVEEHVKVDYK----YLEDLYSNDMNEMDLDLFMDVHELNQIPTEASLEVPYFELQDDVRSMAEILNIFKDSYIFKLRWGNEAALFVERAEDEELDELDELP--------ITLDVLNEEIFLPCHAAYRNIYTSLKDGSIDFEDIDEIFR--AYKGKYEKLAAEVAIMSKQDFNDDQHWVQTRIQQIKQYHELHLAVESAKVVMMVKETLCLQGDFQVLEKLL--ITTHSDFKSERLDSIDNELIQAKNVLVDITEPRRLCLQELGHRKNFVIWVKEALEDINELKVFVDLASISAGENDLDVDRVACFHDAVLGYSSMLYDLKPDAGFSLFNEMLKKLWKALDNDSNLPKKLCDSARHIEWLKTVKDSHGSVELSSLSLASAINSKGIYVINAQNQ--KKLALENILKLHIMEEHDGGCETRVYSLEDLRDLQNKLMLMSGKGEQG-QCEVDQFAEVFASVQRLVSAFIDLYVAGNPLFRHWEANINCNSK-EACIIIDFNLGSVVSVVMVEGDVTEQLPEVCKKMESCLRFWQDFMDKQRSQHYYLNYYTAEQLVYLCHQLAHN--NMEEIDDQVLMMLSFIKPSCSTSDLRKAWHILQYDLIRKGPDQNDDLDFQTFVEVSSMTENESTEKSCPTSDDLIQQLGDASGSTKLGVIWNNYMRDMKAFLPDSLDVPSLGYLLEILANSHREDEGDMSQRDKTRTILRELPNGIASGRPNLIICPSEEILISCISIYMNSKNEPLPTYDEVLLCSATTPYEEVELFLRRCLS-AGYRGKKIYTMLYVNQLNYEVSYKVEKFFQNQNAHTT-NDYRLVLICESNKEHAYLPSAFSQFRLHLIPQQPIPSIQQYLHRHFAVPVGISSAAAVFKDRQNVGVVSSERSGVGKSLYIKRLYEKLKLNSKKPSQ-LKCIRLTEPKVDENVIIQSLISVLKKN---DLSVYHFDVTTMVKKGLHEFLFRLLILGYLMDSKGNMWKSSNKHLYVIEILRPGLSQNDRRAGAKVS----FNFLDVFPIVYCRSPKEVLELEMRMEEHPSFGLSDDPLMDDQEFRSEAYQRPYQYLQRFYNGINLDEFLYQG--VEGSHVECLQMLFEYCGIIDPSWAELRNFAWFLNLQLQDCEKSVFCDFSFVGDTLLGFKNFVVEFMILMAKDFATPSLSISDQSPGRLHEDFSSANEEDLAPFKIRKRWESEPHPYIFFNDDHDSMTFIGFHLQPNAQKGVDAVDPSNNRVIKQNIMTMELYEGLKLQRVPFNIDFDQLPRWEKIERLSRVLGIQWPL-----DPDETYELTTDNMLKMLAVHMRFRCGIPVIIMGETGCGKTRLIKFLCEMHRSGVATDNMKLVKVHGGTSSEMIYTKVREAEAMALRNKLDYGFDTVLFFDEANTTEAISSIKEILCDNSAEGQNLTENTGLKIIAACNPYRKHTDVMIKRLESAGLGYRVRAEETDEKLGSIPLRQLVYRVQALPPSMIPLIWDFGQLNDHTEKMYIKQIVERVAETHSIDSGYITVITDVLSASQKYMRTRQDECSFVSLRDVERCMQVFGWFYKKHLMLLSELDKFESIQRTEKTDQHPKDTDERNPILWSLLMAVGVCYHACLEDKEKYRKKICKYFPAAYS-PMKVMQEISVIQDIFLEGVPMGENIARNNALKENVFMMVICIELRIPLFLVGKPGSSKSLSKTLVADGMQGQAAHSDLFRKLKQIHLVSFQCSPHSTPEGIINTFKQCARFQEGKNLSEYVSVVVLDEIGLAEDSQKMPLKTLHPLLEEGCID-DQPSPHKKVGFIGISNWALDPAKMNRGIFVSRGDPDENELIESAKGICSSDVMILEKVRECFKPFAHAYLRICKKQEKGFFGLRDYYSLIKMMFAVAKACDQKPSAEQIVKAVLRNFSG-KDDVDAVTFFTSRLNIKPELETISAIELVRENVTAIGQ--------DEECRYLLVLTKNYAALRILQQTFFSDQ----CQPEIIFGSSFPKDQEYTQICRNINRVKICMETGQTIVLLNLQNLYESLYDALNQYYVTLGGQKYVDLGLGTHRVKCRVHKDFRLIVIEEKDIVYKQFPIPLINRLEKHYLDLNTLLKSEQKDIVKNLEQWVQCFTDVKNKHSVAPSARRYSPADAFIGYHTDTCASVVMQVTEQLKGQELSDPR----------------------------------------------------------------------------------KGILDESKLILLNCATPDAVVRLDCTSLFNVESEHLSRVYFEDQMHNSLAEFILSHIQQEGCSG-AFFTEVTTFSRLLTASETQQLQNVVQ----NIELLSLQQFDTEQSFLKKIKNYLENTT-GDKILLIQTDFDEGFQKLNVIASAKYSSINEINKFKKEGSGKIFVYFITKLPRMDG------GTSYIGFNGGPWKSIHIDDLRRPKDIVSDIKALQGLTISQLFEEKAEKVD---------ETEAMEVEDMYAGGEDEEDEEKMELEE-------------NNGCKDVLDTTALVRSCVQSAVGMLRDQTEGGMRSTKRVEILLMLLAEDQTLQAEFLKTLKTRLHSLLVAHDDN-TISAKSWVSREALNVDALHEGGTFRHALWRRVQAVVTPFLAQLVSVVDRDCNLDLLLDRNSGEPLKKLWLEIFRDDKFLSVSPYTR-TENNSATKTILVQNYMSVDRNKGCTMPFSWRIKDYLEDLWKHALQQ----EGHT--VKQFEEFFWKTPLGRYISEATNEMQMEFFYRYLQDFISMTMNVTSEVDFEVLRGAFTSSVNEVRIAHEAHES---EALSLVWIHVAYHHFKNRIQNLHRMMSLEPQISQMLLEN--RYASEGKELVLDVLAAVACIEYLEPQNLDGDDQSLAWLRRVKKLQVPVELVCSLESLHNRGDRCRQMVTNIQHGWRRIYSLVLFVEHMLLGVGDLQQKLKPVVLEHTQLLAQVLEQDSNLKKKKPFEAVITVLKTCKDKASQRIIRFGLQLCPVCMGDPRDPLSLPCDHIYCLTCIRQWLVP-GQMHCPLCVQEVPDNFELKPSD--ELRRLISQNASFRMRCNAFFIDLVSTMCFKDNTPPSKDIILHLLSLLMVEASSLPPFKGRDRRFLTKALSPFDDSVDKNPVVRSVVLKLLLNYSFDHVKDYLQQHLTEVEQSKILEETDKAELYCLYMNCLEDSMYDRTQWHTVAEQQNCFLEETRFLLEFLQS--DSVSAHTATVEHLQRLARVRLCLDMAADLLVANAGIHDDPSAFIQAFWNNVVNLCRQSRNDWYRVYLIRKLCSLQGVECVKNLLLQET-YRWLFPQEILEMN----QDDSQIDQYLACGADYKTIRDAVAKFMLDLHINGIQKAIEDCNCTPMKKAVYVLMAFFREVTSLHRTGNPNMHPKPEHCAGLEHFIKNSAIFVNNEMKAFAEKLVRNQLG----ALRVRPHMPSRDLSLVEVTIHMAAVLLCGNLLLLQPLQKLALSPNNMMASFIPTMPDDMLAVAQ--QAMGHLQWYFCPNGHPCTVGECGQPMEVSRCPDCDAEIGGSNHRPVDGFRAMQIQADRTQSGHILGDAQRRDLPDMQDTKNMSPAPFALLRLLTHMSMLIGTQNNPQSIMQIIKPAVVHPDAFLMQHLLKDMEQLSKALGKGVDDTVSTIHLAIHSLLEPHQTS--QWPDPYDPNLSTKDARNGWENAMNNDVITHHLKVLEHQLKEVNAFIREDERVSSNPVMKLTFGEPGRFLRSLPQNSLIHNSSIWSCRNKVSLMSLTHIVEQNNGRDTLPVLWRFLQREAELRLVRFLPDILVLQRDLVKKFQNITDLTYKTIREFLQDQKAASLTAWYEKRIKIFLTTWNQIRVSLANTGEIKLPADYTEKDLGLDADLQVLLPQRRGLGLCSTALVSYLITIHNDLMYTVEKHTGD-DSDYKISPAELTELHVIRYEYDRDLLPLVLANCQYSMECGQETLLEYDLPKIQQQILTRFLQGKPLITINGIPTLVNRQDRNYEIIFKDVKGKVQQELLQPLTQYDLVKELQSYSDVCEALSTVELAVGFLAMTGGEPNMQLGVYLKDVLQMTDHMATHVFKALSRCSLKHCVALWQLLSSLKSETMLRLKRDPFVGISKEYKQPLQEEHKRLLTSFFTKSSADAFLLEMHEFLLLVLKSP--KATDTYRPDWRLKHTVVSYMERKDLDVPPEVEEFFPKEILLSEYTSTWNFSVNLRQKRSQS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB13A8X0-1", "uniprot_id": "A0AB13A8X0_DANRE", "id": "A0AB13A8X0-1", "name": "RING-type E3 ubiquitin transferase", "aln": "MTRKRKSGKKGKPLAQKKEAQKRGGSTSSSTTQKEGAQKGDGSSSSSTTQKD--------------------------GAQKRDDSTSSSSTAQKEEGQKSDGSTSSSTTNKEGAQKRDGSTSSRLQKKGP-------------------------------QKRKGSTSSSRAHSRSRSKSKQTSYPSQARSRSHGQHNISTTESGPLSKEAQTQTSASLLVDKDTQTETVGQASQQTQTEINGNTETAEVSQPPQLSHEDVEMEGTVQPRTKGSESDGEKEESVKR---------------KKRKLSEIGEPAKETEDSTKLSHECEEKVGDNQKNEDTNKHYGGDSLKDLKSVTEEPKSYAAAAATGKTGKVSKEQTNQIEANQDSTMESKSTQRKPSPVRAPAGPP-------------MLTFYIYAVLDKRFRFNEQYDSLFLDYG--------NGNIKLQMKHFNIGKDGYLIEATFSVEDSAVRGGTIQYKYVVQQR---------------QNQKSEIAVRYIEVPSYTTEK--EFHLYEGYISCSSTVSITEWMMSLFHS-EQKAVYKGWETSAHVLLDRIFLKWHPSNEESNMTFVQHLRSYKNAFESGFVEFPG--NYTPFPIKVSELISAKLRMILKKESEALR----TSESLDGVKSEALSVALSVFKVCCGCDVDLSLKDWGKLCQVVSECMGSFG---------EIQTTQTAPFINTVTGLMNLCAKKLITEVVLLVPVLHLLRNSEVNEAGPGSSMD---EQRWTGLENISYQSFRERIRGLPDKRRMILKLIKDNLPMTKDNPKLLKSWLSLVAFEDVSEFVQLTGSFPELLIQSLMCRIIEAEKNTDANRTEKNLEVTG------KVLNLLLKSIKKDRERIMKTEQLKLILQCCCNVHKSVCKTARLVPQYKVTVLSFQLLLKMAEIVYDGFFKGGEQMKQHQNEVLSKLNIIQEDFRKWRVELLLKPLMQT-------TGFTYPREMELWNDLYGIESSIPGVTERWKGFLDHDLRRRISQISDTDKIVVYVLVTSAKAVENSHANIQSCLKELCEAAIKNQCQSKKEGTLLCHLFSKTISWPVLSSIIVESAACFG-----------EDHKGRLLDPQSAINFFLSQ--DKWNEWKLEDGASQLIAESQSFLGRLIQTLCQGSIPLGHLKTIFKYKTQFQKLYNQYKNN-NKEMNVSISVSDLLSQREDDLKAFEQQKGYMTNLINMLGKISDVINVPELSSLEEIAKTNVQEVALDKLVEVETYFSKDDLKKNNTRRVLFYSDDQQVQDMAREMHDVNSSNLILSFWQEKAKDYFMAGPELLS---------------LDLTEIYEDIWTPCLTKFLNFGNRIAVGQACFKEVEEALVGCGETGEGDRLKKEFMLMATMLDGHNENWPEQRLKQIREYRCLYDAAESAEVILKLKDRLGLQGDFSHIHSLT--LVRDDSFKQNTLGSLSEDLIKARQKLADVERRHTACLEAFLKSDTLIKWIKAEIPSLKELKVFMELATISAGENDADIDRLASFETAVMGYAPLLYSLPQNVGFEEFFDYAKQVLDTLNKDEKLGDKLVDSNRWLDWLKGLRETHGSVEQSSLSLASAINTGGVYHVGWPDDFNGKTGLDNIFYVKVTKNN----EEKTYRLNELLELQNKLMLMSSKGEKG-KEQVIKFTQVFEGIQRMGRILLQLHRSGNMLFRNWAAEITCNHQNQPCIQVKFPL--LSKCIVYQGEVEEELQKLSRSLEDFHKDWCNHLTKMRSQYYPLNHYSSEQIVYLCEWINSINIKKKPVPQQVWHLLTPIKPDCMLNDIKEAFEIATEPQSILQEDT------AEELGPNSDFDLP------------LSFSLLDVSTECLEDLWKQFKENMSGFLTHHVDVETLGRFLSNLSNMNQLH------------IKRKIPSFLQEGRPNLVQCPAAELMSTTLSFYMESPENPLPTTDEVLMCQEETTEEEVEIFLRRCLGGAASNHKKIYTLVNPGSMSYDVSVALVEYFETQEVCAG-PYYRLVMVCPVN-QDRYIPSFFSNYKVQTGITISAERSQKYIRHHFKISYELATHSSVYPERLSVWMIASKRPAVGKSLYVRRLFEKFKG--EFPRATLLTIRLIDPYIDMDGFVQTLSERLAPLRQQDPVLLHIDVAAVCHG-LEEFLFKLLILECISDSKGTIWRRNKAHLVVIETLQRGHKTQTKME-------PSHGFLNTLPTIFCRPPKDIKEIMKTNESFR----SLDPLMDKEEFESEDIQRPYQYLRRFNRSMNLDRFTYQAHSVEGDPVDCLHHLLSNYGLKDPSWAELKHFTWFLNLQLKDCEKSLFCDSDFCGETLSGFKDFIVKFMIHMARDFASPSIDISDQSP-----SFFSKNEDEEEILSFRKRWENESHPYIFFNADHVSMSFLGFHVKQN-GTILNAVDSKSGKVLMRNVMTQELFSDIQRQMINLSKDFDDLTREDKLQKMSFVVGAEKGCEKGKFDPDPTYELTTDNVMKMLAIHMRFRCEIPVIIMGETGCGKTRLVRFLCDLQREGRDVENMKLVKVHGGTTSETIYKKVREAEELAQKNRQKYKLDTVLFFDEANTTEAIFAIKEVLCDKTVKGYPLKKNSGLKIIAACNPYRRHTTKMVDRLERAGLGYRVKAEETEDRLGKVPMRQLVYRVHPLPPSMVPLVWDFGQLSDSTELSYIRQIVKKKMRDHRLPLSCQNVITNVLAASQKYMRNQADECSFVSLRDVERSMGVLLWFYNHRDIFFPSQDFPRFEN--------------VQMVLKCLVLAVGVCYYPSLENKRPYLATISKCFPDQFNSEESLEQEIASCQDFLLKNIQTRETIAKNMALKENVFLMVVCIELRIPLFLVGKPGSSKSLAKTVIADAMQRQASHCDLFKKLKEVHMVSFQCSPHSSPEGIIGTFRNCARFQKDKNLDEYVSVVVLDEIGLAEDSPQMPLKTLHPLLEDGCIDSDNPESYMKVGFVGISNWALDPAKMNRGIFVSRWDPSEKDLVETAEGICSSSQPVLLKIKHLLSKLAKCFLSICKTDSEQFFGLRDYYGLIKMLFDTVKCSDQEPSDKELAEAVLRNFSGQRDGFDPLDYFKDIFQNIQNVQRPNTLNMIEQNLDHHID---------KECRYLLLLTTNNAALYIIQHHIFSKENYTQKCPEIVFGSGFPKDQEYAQICRNVSRIKACMETGRTVILLNLLNLYESLYDALNQYYVYFSGQQYVDLGLGSHRVKCRVHRDFRLVVVEDQEKVYKKFPVPLKNRLEKHKVDRSTDLAPWQHRVLEKLKKWAREFSKIQHSDSSEAN---FSVTDAFVGFHGDACASALLQALKKIDKLHHNKEENREESEAHHIDREFTEFQEKVNKFPDEAQEDDASMEVDKVQDAEIDEEMETLEDDSDLVKMVEGPVFVETRDKIESNKTMDEEEVYEIAKSFLLNCSTPDSVLRLKYSEFGNQETEELQKMYFHLQTHQSLRDLLNNHLNKTNQDK-NRFLEVTTFSNLLTGADVRNLGPALGLSTERFLLLSLHQFDTEASFCNKIQSFLRESGPSVHILLIQMDMEESLCKNELIASAKYCTMNEILHLK-SDECNIYTVFITKLSRIGEQCTSITGDKYIGFQGGVWLSAHIDDLRDSDDLCLNLKAFCGIPISQLIS------------------QTIESDVKES---DEMNTNRQQSEK---------------GDSVHLHSLSLLRSCTQKAVSLLRDTDEKTSRSMERMNILLGLLACDPGRTGARFQQVLLKRLVFALIQKEELIPNAKDWVYKVAKNHEALQECGTLRHTLWRYLQDFLTPVLARILEVIDRDCNLYQLYGEGLSEGLTQFWLDIFEDQQLLDLIPSQNTRAPDQEINVQCHLFVGEVEQP--CAAPYSWLIKTYCQSLWEESEFVRSSEQDIKARIQQFVSAVSGSRLGSYIQKLSDVENVELGQRYLTDYVLLAFKVNSEDEHWVLQSAVLGCVFTLQTMMSVSPE-----LSPSWIHAAAQIYNPRMDTLSHVLQLNPQLVSLIQQERPKRESP--DMCEDILAVGICVEETKLLPVTSLTECLTFLQRVEQLQPCIERVLSPDYSALCSPGCLKYLETIQSVWQGILLVAVFIEKVVIKMKKGDERIIALTLKHCSQLHGLVEGSPDFRSKDNLQQIIRILNDYHEESISSELRYGVK-CRVCLMELSEPFALPCEHVFCRSCLRRSMEREEAQHCPVCREPLSNNYQPTVSTTLNYSFALKQHKEIIKCCNTFFLEVVSRFCLTDDQDPPDDLVELLFSLLISAQG---------DVYKTRELTPFLECVDQSPVVRSVLPKLLMQYSLKQVKKHIQSYLEDLEN-KLLDKEDRTELYRLFVNCFQDTLLCSDSNG----DHKHLRENTNFLSRLARKQTPSRQN--DPAEFLMSMARLRMCLDSAAYILSKAICQKNNFVEAEFKFMEQVKAVCDYCDNDWYRVYLLRALNRQAGMDFLQAL-INSTDYEWIFPAEMMRLHR---LIPAEVDRFLCCGQSYRALRDGVGESTQVGTTDGLKEALQASVGSSPLKNALLTLAVFRQVTCHFMSPERTLHPQEQQISILEKVIRDN---MSGHAREFCTALLSNHIGGPGSNLRLGTGVPAQRRPVLELLVHACTVFYSGN-RLISPLFNIASQPQNMTGAFLPTMPDDHTSEAKQWLSEKKLKMYFCSNSHACFVGECGRPMAKSKCATCGVEIGGEGHIPVPGFTEAYGDYDRTRPGHILGQARTRSEAPNRK---LTLAQSCVLRLCLHLAMLQGLIHYQQGIRNMIHPEVSDVYQFLWQHLEKDMEVLGKTLTLNIDDSAIVIHLIFSRFLQTTPVAN--------VDLSTRKSREQWEITVCKTAISPVLQNLDRELNNAQDLIAADNRLSNSPLVKVLRGDP-QRMLQLPANCPTEHSAFWSPSSVLAVESISQQIDQ----AQAPLLTLFVQKVHYIRQLDCLPALAALLSDLIKVLPPGSETQNHTIASLLHCIPAGHQKKLMSERVEIYMKVWNQLRMEISSNASLGLDSTHCEKDITSESSGQFLFPSRKGAGSCLHAVIDVLSETHNSLVREARKLCQQTDSDYKVPLAVLSKSQLALCHPEREFLPLVLANCHYTLEKGQQTVSSYDHQGIERELSRRFFAGKPRIQTD-TEKYLRRHHQNFTEVLNEVRAKIPQKVSGSSCSTNQHQVHHGASFGGEGHHFFSRSR----QSSGGTYLG-------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. : . : * :: . : . .. .* . : . ... . ..:: . . ::.. : . .: . . .: . . . . .. .:. : . . . .. :. .. . :: : . : :. : . . : : .. :: ... :*. ::*::. * ** : . :: * : :: . *:*. . * ****: . : . * : : * . ::* * . : . : . : . :* : :* : :. ::*: * :. . . .*. :: .: . :: : : :: . : . . .* :: : :. : . ** : . : : * : :*:** . *: *:.*:.: . : *:::: : : *::**: ::.:. : . :: : . . : : : : : : . : : :*. . : . : . . : . :: : * : :: : : * :*. : * *: : *:. : : :* : . : .:: *:.. **::.. . . : . .: : ** . :.* :: :: . . . :. : *.: .: * *.* : *: *:: :. * : : . : :. *.::: : ::: *: .:.. ::* : ::: * .. . .: . :: .** :. ...* :: * : * : : * : : :: *. : .: : *. : ::: : .: * :. :*.. . . * . *: **::*: *: *. :*:*:: :: * : ***. :. * ..* : *..:. ::*:*:: * *: . : *: : :: *:: : .::*****::**:******* *:**:*.*. ** **:.:*:.: ..*. * . ::: :*::*. * ** ** * ::*** :.::***** ***:**:*** *:* : . * . :.:: : : . : * ::: :* *******.: ::. : :* *::** .:**: ::.*: :** *** * * * : :.* : . : *:* : * :.:.:* * : : * :: ** *::**:***. : : . :*: ** .* :: .* . * : : : .**. :*: :** * *: : * :* : *:***: * *:: : ::.**: :**** ****:* *. *** ::***** :*:*::: ..:.*:*. : *.. . *:**::* :. *:** **:.:: . * *: *: :. : ::*: : * :::*:*..******:. *. *:* . * *** :* :* . .: :* * : *:*::: : : ***:**** : * :*.:* . ** ::* . : . **: :* : **.**:: :: :* ** ** ** *******:** . :** * *: *** :**: :: *: :***:**::*: *** **:*** *:**. * *:** ***.*:* **: **:***:*:: ***** : *:: :.:*****.*.***:*** *: :*:*:***:: * ::*:. ...:: :::** :*:..: * : :. :**.*.* .*::::. .:* *** ********::*:**:.***** ****************::**.:::* . .:.:*********:.. **.:*::** * *: .: ::*:*********:*: .***:***. . * * :::**::********:*: *: *** ******* *** ::**.:*:*******:.****::**:******.* :* **:***:: : **::**.*** :**. :**.*********.: *: **:.: ::: . : :* .*::*:****:..**.* * *.: :* :. : :*:: **::* . .**:* *******:**:****:***************:* ::**.** *: .:**: **::*:*********:*:***.**::*****:.*:* :*********:****** :***********:***: *:* .: :***:******************** .*.*.:*:*:*:*****. : ::: : :*:.: :*: :.: ********.****:* .*...: * .::..******** :*..:.: * : : ..::::.:*: : :.****:** * .** *:*: :*. ***:***.**:****:*:***:.*:* *****: ::**** *************** :.**:*******:******** ***:*:*::: ***:**:** ****** :* .* * *: ::::* *.. * .:: . :* :*.*:*:* .:***.::*. :: .. . : : :: :**:*:***:*:**. .: . :: *.: *: * *:*: ::: *:. . * *:****.***. : * : . :* *:*:*** ** :.::. * :. ::*::* *:::. . :::***** :*** : : . ::. *:***.*:. * *:**:** * * ****** . : ::. : :.****: : :* : : * : : *. . *.: *::**.* **.:*** * *. .*: :** ** : . :: : : :.:. .*: : * * :**:* **:**:**: :* :**.** :: :*** ** * . .:*: *: * :*.: . . .: . *:** *: * :.** .: . ::* . . : ** :: : : :: ** *:: :::.*.:. : .*: *. .. :: . . :* *:* * : :. *::.: ::: : **: : : . :: * :*. * * : . .:*: *::*. :* : * . : :: * * .:*:*:::: . .: :. : * :. ..:.:. : :: * :: : . *:*:: * :* : :*..***:*:.* *:: : ** * :.:::. * :.:: : **:**:::** :*:.*: * ..:: *:***: *: *:** : **:.**:***: ***::**:..** ::*.:* ::: * : *::*** *::.*::*:: . : : *: .** ..*.* :**:*:*** ** :* : : ::* .* ***:****:* * *:: :: : .*:** .:: : . :*::* * .*:::**. .: .: *: . . : . . ::.: :*: . : : .:** :: :.:.* : . *. *: * : *: . .: *: :* .::: .*: ::.** ::* * .* :*:****:* *: . .: * *...*.* *****:** * * * :** .* * ** . ***:.**:**..: . . . : ** *:::* * : *.: :*:* * . ** **: :*:* * * * . *:: .:** : :*. ***: *: ** . : *: *:: * : * *:*:*..*: *: *:* : ** :. . * :** ::: : : ::* *:* *:*: :* : ** : .* **:* : :* :: : .*: :::..** :* .: ....: * : .*: ::. :.::* *:* * * *::. * **.:: ..* : :..*.: : ::. :: . :*:: **:*:**:* :: * :* .:* *:::: **: *** : . . : *:. *: :: ::: *: *. :. * * .. : :.* . : ", "identical_positions": 1204, "similar_positions": 1452, "identity": "21.94%" }, { "cls_id": "homologset.agr.MGI:1289213", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5M845-1", "uniprot_id": "CD033_RAT", "id": "Q5M845-1", "name": "UPF0462 protein C4orf33 homolog", "aln": "MDFKIEYTWDSFPVSHEPVRIRLNPCDKGLKMEVSAPFFNDPPAPLGEPGKPFSELWNYEVVEAFFLNNTTEQYLEVELCPHGQHLVLLLSGRRNVWKKELALSFKVSRGETHWEGEAFLPWSYFPSKVTRFNSFAIHGSNDKRVYEALYPVPQPELQQGQNPDFHRLEYFKPFSFNTLLGEEWKQPESDLWLIEKSDI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BGN2-1", "uniprot_id": "CD033_MOUSE", "id": "Q8BGN2-1", "name": "UPF0462 protein C4orf33 homolog", "aln": "MDFKIEYTWDGFPVRHEPVCVRLSPCEQGVKMEVSAPLFNDPPSPLGEPGKPFSELWNYEVVEAFFLNDTTKQYLEVELCPHGQHLVLLLAGRRNVWKKELPLSFKASRGGTNWEGEAYIPWSYFPPNVTKFNSFAIHGSNDRRVYEALYPVPQHELQQGQKPDFHRLEYFKPFSFNTLLGEEWRQPEPDLW-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N1A6-1", "uniprot_id": "CD033_HUMAN", "id": "Q8N1A6-1", "name": "UPF0462 protein C4orf33", "aln": "MDFKIEHTWDGFPVKHEPVFIRLNPGDRGVMMDISAPFFRDPPAPLGEPGKPFNELWDYEVVEAFFLNDITEQYLEVELCPHGQHLVLLLSGRRNVWKQELPLSFRMSRGETKWEGKAYLPWSYFPPNVTKFNSFAIHGSKDKRSYEALYPVPQHELQQGQKPDFHCLEYFKSFNFNTLLGEEWKQPESDLWLIEKCDI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6P2T7-1", "uniprot_id": "CD033_DANRE", "id": "Q6P2T7-1", "name": "UPF0462 protein C4orf33 homolog", "aln": "MDFYIRHTWDSLPVDHKPVKIRFSPGEDGLLMQVTAPFFNDPPAPAGPPGEPFPGLWDYEVVESFFLNSETEQYLEVEVCPYGQHLILLLNGKHNAFMQQLPLSFRANIEDSTWHGEALLPWRYFPQGINKMNSYAIHGSGAGRTYESLYPVPREDLQEGQGPDFHRLEYFQDFTLQSIMGEDWVQPESDLWDLARK--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** *.:***.:** *:** :*:.* : *: *:::**:*.***:* * **:** **:*****:****. *:******:**:****:*** *::*.: ::*.***: . : *.*:* :** *** :.::**:***** * **:*****: :**:** **** ****: *.:::::**:* ***.*** ", "identical_positions": 106, "similar_positions": 55, "identity": "53.27%" }, { "cls_id": "homologset.agr.MGI:1289222", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0U1RPG8-1", "uniprot_id": "A0A0U1RPG8_MOUSE", "id": "A0A0U1RPG8-1", "name": "", "aln": "---------------------MSLPANQIKEPGKQSQPAKSLKEPSQEALPVNLLKESSQESRILCPDPAIVVELNVGGQFYTTTMGTLMKHPGSKFSEILSRSARHYKDAQGRFFIDRPGTYFGLLLDYLRTGQVPTEYVPEVYQEAKFYQIHLLVKILEDMPQIFGEQVARTQFLMGVPNYRENLEVLLHLARAEAVAMRSSKVVVCVVRTEEEDAKCVEPLHILEAKKT--PVVKFGPWKAGPMTEDFVCCLEKDIRAKGYKVTS---QRYHLSR----DPYTC-FWIFVFTWW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1M0C4-1", "uniprot_id": "F1M0C4_RAT", "id": "F1M0C4-1", "name": "", "aln": "MTLNSDPLFFLPLPPRCWNYRMSLPANQIKEPGKQFQPAKSLKEPSQESLPGNLLKEPSQESRILCPDPDIVVELNVGGQFYTTTMGTLMKHPGSKFSEILSRSAKHYKDAQGRFFIDRPGTYFGPLLDYLRTGQVPTEYIPEVYQEAKFYQIHPLVKLLEDKPQIFGEQVARMQFLMGVPNYRENLEVLLHLARAEAVAMRSSKVVVCVVRTEEDDAKCTEPLHILEAKKT--PVVKFGPWKAGPVTEDFVYCLEKDIRAKGYTVAS---QRYHLSR----DPYTC-FWILVFTWW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BQ13-1", "uniprot_id": "KCD14_HUMAN", "id": "Q9BQ13-1", "name": "BTB/POZ domain-containing protein KCTD14", "aln": "---------------------MWQGCAVERPVG---------RMTSQTPLP--------QSPRPRRPTMSTVVELNVGGEFHTTTLGTLRKFPGSKLAEMFSSLAKASTDAEGRFFIDRPSTYFRPILDYLRTGQVPTQHIPEVYREAQFYEIKPLVKLLEDMPQIFGEQVSRKQFLLQVPGYSENLELMVRLARAEAITARKSSVLVCLVETEEQDAYYSEVLCFLQDKKMFKSVVKFGPWKAVLDNSDLMHCLEMDIKAQGYKVFSKFYLTYPTKR----NEFHFNIYSFTFTWW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A2R8RRJ7-1", "uniprot_id": "A0A2R8RRJ7_DANRE", "id": "A0A2R8RRJ7-1", "name": "", "aln": "---------------------MSLPD--YKTIG------------KQSSAP--------------VQSKSQVVHLNIGGHVFSTTLGTIRKFPNSTLAELINGSSKR-MDSEGRYFIDRDGTLFTHILEYLRTEKLPCEHLQEVHKEAIYYDIKPLVKAIEETPQFFGETVGRQQFLARVPNYRENLEVIVRVARAEAIASRHSNIIVCVLRTEDDLSRYNDAIDSLDAPRE--SVVSFGPWKAPASVEDLLDCVKMDIEAKGYKVKI---QAHSVDKGFLFKSYDF-FYKLVFTWW", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : * .* . * **.**:**...:**:**: *.*.*.::*::. :: *::**:**** .* * :*:**** ::* ::: **::** :*:*: *** :*: **:*** *.* *** **.* ****:::::*****:: * *.::**::.**:: : : : *: : .**.****** .*:: *:: **.*:**.* : .: . : :: :.****", "identical_positions": 92, "similar_positions": 81, "identity": "30.98%" }, { "cls_id": "homologset.agr.MGI:1289225", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5FVN2-1", "uniprot_id": "TM41B_RAT", "id": "Q5FVN2-1", "name": "Transmembrane protein 41B", "aln": "----------------MAKGRVA-------ERSQTEMLHSTPAGDRA-----VGTQGSAAPGNKDHLKEKPCVEAGSARTSLLILVSIFSCAAFVMFLVYKNFPQLSEEERVNMKVPRDMDDAKALGKVLSKYKDTFYVQVLVAYFATYIFLQTFAIPGSIFLSILSGFLYPFPLALFLVCLCSGLGASFCYMLSYLVGRPVVYKYLTEKAVKWSQQVERHREHLINYIIFLRITPFLPNWFINITSPVINVPLKVFFIGTFLGVAPPSFVAIKAGTTLYQLTTAGEAVSWNSVFILMILALLSILPAIFQKKLKQKFE-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K1A5-1", "uniprot_id": "TM41B_MOUSE", "id": "Q8K1A5-1", "name": "Transmembrane protein 41B", "aln": "----------------MAKGRVA-------DRSPTEMLHSTPAGDRA-----VRTQGSAAPGSKDHLNEKPCAEAGSARTSLLILVSIFSCAAFVMFLVYKNFPQLSEEERVNMKVPRDMDDAKALGKVLSKYKDTFYVQVLVAYFATYIFLQTFAIPGSIFLSILSGFLYPFPLALFLVCLCSGLGASFCYMLSYLVGRPVVYKYLTEKAVKWSQQVERHREHLINYIIFLRITPFLPNWFINITSPVINVPLKVFFIGTFLGVAPPSFVAIKAGTTLHQLTTAGEAVSWSSVFILMVLALLSILPAIFQKQLKQKFE-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5BJD5-1", "uniprot_id": "TM41B_HUMAN", "id": "Q5BJD5-1", "name": "Transmembrane protein 41B", "aln": "----------------MAKGRVA-------ERSQLGAHHTTPVGDGA-----AGTRGLAAPGSRDHQKEKSWVEAGSARMSLLILVSIFLSAAFVMFLVYKNFPQLSEEERVNMKVPRDMDDAKALGKVLSKYKDTFYVQVLVAYFATYIFLQTFAIPGSIFLSILSGFLYPFPLALFLVCLCSGLGASFCYMLSYLVGRPVVYKYLTEKAVKWSQQVERHREHLINYIIFLRITPFLPNWFINITSPVINVPLKVFFIGTFLGVAPPSFVAIKAGTTLYQLTTAGEAVSWNSIFILMILAVLSILPAIFQKKLKQKFE-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1A5V7-1", "uniprot_id": "TM41B_DANRE", "id": "A1A5V7-1", "name": "Transmembrane protein 41B", "aln": "----------------MAKKRAG-------NRE----TESSPLVEQE-----PRPS-KETPVPKGAQSP----GGASARMSILLLVVIFACSACVMYLVFRNFPQLSEDEREKIKIPKDMEDAKALGTVLSKYKDTYYTQVLLAYFATYIFLQTFAIPGSIFLSILSGYLYPFPLALFLVCLCSGLGASFCYMLSYLVGRPMVYKYLTERAQKWSQQVDKHREHLINYIIFLRITPFLPNWFINITSPVINVPLGVFFLGTFLGVAPPSFVAINAGTTLYKLTTAGEAVSWNSLLVLGVLAVVSILPVCFQKKLQQKLE-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VX39-1", "uniprot_id": "TM41_DROME", "id": "Q9VX39-1", "name": "Transmembrane protein 41 homolog", "aln": "MSYCSGVAISADEGITMRNGRAKALQEHSPDQVATPLLPQVPPQEQQDLNPQQQQQQQQQQQATPQKQAMSADEKKATKKSLVIVAGIFVASLVTMCYVYAIFPELNASEKQHLKIPRDIQDAKMLAKVLDRYKDMYYFEVMFGVVVAYVFLQTFAIPGSLFLSILLGFLYKFPIALFLICFCSALGATLCYTLSNLVGRRLIRHFWPKKTSEWSKHVEEYRDSLFNYMLFLRMTPILPNWFINLASPVIGVPLHIFALGTFCGVAPPSVIAIQAGKTLQKMTSSSEAFSWTSMGILMACACASLLPGLLKNKFKHKKEA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : *. :: * : . ::: *::::. ** .: .* *: **:*. .*: ::*:*:*::*** *..**.:*** :* :*:.. ..:*:**********:***** *:** **:****:*:**.***::** ** **** :: :: .::: :**::*:.:*: *:**::***:**:*******::****.*** :* :*** ******.:**:**.** ::*::.**.**.*: :* * *:** :::::::* * ", "identical_positions": 120, "similar_positions": 95, "identity": "37.5%" }, { "cls_id": "homologset.agr.MGI:1289227", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VIL3-1", "uniprot_id": "ZWINT_RAT", "id": "Q8VIL3-1", "name": "Outer kinetochore KNL1 complex subunit ZWINT", "aln": "MADAEKNAVAEKNAVAEENAVAEENAVADKNATKEVLAEAASVLEPVGLPEEAELPAKIMEEFMRNSRKKDKLLCSQLQVVNFLQTFLAQEDNTDQNPDALASEDTSRQKATETKEQWKELKATYMDHVDVIKCALSEALPQVKEAHRKYTELQKAFEQLEAKKRVLEEKLQLAQKQWVLQQ-KRLQNLTKISAEVKRRRKRALEKLDGSHQELETLKQQAGQEQEKLQRNQSYLQLLCSLQNKLVISESKADDKDVKG--PALPPKSP------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CQU5-1", "uniprot_id": "ZWINT_MOUSE", "id": "Q9CQU5-1", "name": "Outer kinetochore KNL1 complex subunit ZWINT", "aln": "MADAEKNAVAEKN-----------NAVA----TKEVLAEAAAILEPVGLQEEAELPAKIMEEFMRNSRKKDKLLCSQLQVVNFLQTFLAQED-TEQSPDALASEDASRQKATETKEQWKDMKATYMDHVDVIKCALSEALPQVKEAHRKYTELQKAFEQLEAKKRVLEEKLQLAQKQWVLQQ-KRLQNLTKISAEVKRRRKRALEKLDGSHQELETLKQQAGQEQEKLQRNQSYLQLLCSLQNKLVISEGKAEDKDVKG--RALTAKSKSP----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95229-1", "uniprot_id": "ZWINT_HUMAN", "id": "O95229-1", "name": "Outer kinetochore KNL1 complex subunit ZWINT", "aln": "MEAAETEAEAAAL---------------------EVLAEVAGILEPVGLQEEAELPAKILVEFVVDSQKKDKLLCSQLQVADFLQNILAQED-TAKGLDPLASEDTSRQKAIAAKEQWKELKATYREHVEAIKIGLTKALTQMEEAQRKRTQLREAFEQLQAKKQMAMEKRRAVQNQWQLQQEKHLQHLAEVSAEVRERKTGTQQELDRVFQKLGNLKQQAEQERDKLQRYQTFLQLLYTLQGKLLFPEAEAEAENLPDDKPQQPTRPQEQSTGDTMGRDPGVSFKAVGLQPAGDVNLP", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* **.:* * *****.*.:****** *********: **: :*:************.:***.:***** * :. *.*****:***** :*****::**** :**:.** .*::**.*::**:** *:*::*****:***:: ** : .*:** *** *:**:*:::****:.*:. : ::** .*:* .***** **::**** *::**** :**.**::.*.:*: ::: . ..:. ", "identical_positions": 135, "similar_positions": 74, "identity": "45.15%" }, { "cls_id": "homologset.agr.MGI:1289230", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4FZZ1-1", "uniprot_id": "PXK_RAT", "id": "Q4FZZ1-1", "name": "PX domain-containing protein kinase-like protein", "aln": "MAFMEKPP----ARKVLLDDTVPLTAAVEASQSLQSHTEYIIRVQRGISAENSWQIVRRYSDFDLLNNSLQITGLSLPLPPKKLIGNMDREFIAERQKGLQNYLNVIMANHVLSNCELLKKFLDPNNYSANYTEIALQQVSMFFRSEPKWEVVEPLKDIGWRIRKKYFLMKIKN---------------------------------------QPKERLVLSWADLGPDKYLSDKDFQCLIKLLPSCVHPYIYRVTFATASESSALLIRTFNDKGTLKDLIYKAK-PKDPFLKKYCNPKKTQGLELQQIKTYGRQILEVLKFLHDKGFPYGHLHAANVMLDGNTCRLLDLENSLLGLPSFYRSYFTQFRKINTLESVDVHCFGHLLYEMTYGRPPDSVPVDSFPPASSMAVVAVLESTLSCEACKNGMPTVSRLLQMPLFSDVLLTT-------SEKPQFKIPTKLREALRIAKECIEKRLTEEQKQIHQHRRLTRAQSHHGSEEERKRRKILARKKSKRSAVENSEEQPVKHSNANNSAGSGASSPLTS-------------PSSPTPPSTAGLSSALPPPPPPPPPP--------PPPAGPSP--GTEMPAPPLPQAVNGVN----RGALLSSIQNFQKGTLRKAKTCDHSAPKIG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BX57-1", "uniprot_id": "PXK_MOUSE", "id": "Q8BX57-1", "name": "PX domain-containing protein kinase-like protein", "aln": "MAFMEKPP----AGKVLLDDTVPLTAAVEASQSLQSHTEYIIRVQRGISAENSWQIVRRYSDFDLLNNSLQITGLSLPLPPKKLIGNMDREFIAERQRGLQNYLNVIMANHVLSNCELLKKFLDPNNYSANYTEIALQQVSMFFRSEPKWEVVEPLKDIGWRIRKKYFLMKIKN---------------------------------------QPKERLVLSWADLGPDKYLSDKDFQCLIKLLPSCVHPYIYRVTFATASESSALLIRAFNEKGTLKDLIYKAK-PKDPFLKKYCNPKKTQGLELQQIKTYGRQILEALKFLHDKGFPYGHLHAANVMLDGNTCRLLDLENSLLGLPSFYRSYFTQFRKINTLESVDVHCFGHLLYEMTYGRPPDSVPVDSFPPASSLAVVAVLESTLSCEACKNGMPTVSRLLQMPLFSDVLLTT-------SEKPQFKIPTKLKEALRIAKECIEKRLTEEQKQIHQHRRLTRAQSHHGSEEERKRRKILARKKSKRSAVENSEEQPVKHSNSNNSAGSGASSPLTS-------------PSSPTPPSTAGLSSALPPPPPPPPPP--------PPPAGPSPTSATEMPAPFLPQPVNGVN----RGALLSSIQNFQKGTLRKAQTCDHSAPKIG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7Z7A4-1", "uniprot_id": "PXK_HUMAN", "id": "Q7Z7A4-1", "name": "PX domain-containing protein kinase-like protein", "aln": "MAFMEKPP----AGKVLLDDTVPLTAAIEASQSLQSHTEYIIRVQRGISVENSWQIVRRYSDFDLLNNSLQIAGLSLPLPPKKLIGNMDREFIAERQKGLQNYLNVITTNHILSNCELVKKFLDPNNYSANYTEIALQQVSMFFRSEPKWEVVEPLKDIGWRIRKKYFLMKIKN---------------------------------------QPKERLVLSWADLGPDKYLSDKDFQCLIKLLPSCLHPYIYRVTFATANESSALLIRMFNEKGTLKDLIYKAK-PKDPFLKKYCNPKKIQGLELQQIKTYGRQILEVLKFLHDKGFPYGHLHASNVMLDGDTCRLLDLENSLLGLPSFYRSYFSQFRKINTLESVDVHCFGHLLYEMTYGRPPDSVPVDSFPPAPSMAVVAVLESTLSCEACKNGMPTISRLLQMPLFSDVLLTT-------SEKPQFKIPTKLKEALRIAKECIEKRLIEEQKQIHQHRRLTRAQSHHGSEEERKKRKILARKKSKRSALENSEEHSAKYSNSNNSAGSGASSPLTS-------------PSSPTPPSTSGIS-ALPPPPPPPPPP--------AAPLPPAS---TEAPAQLSSQAVNGMS----RGALLSSIQNFQKGTLRKAKTCDHSAPKIG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LVS2-1", "uniprot_id": "Q1LVS2_DANRE", "id": "Q1LVS2-1", "name": "PX domain-containing protein kinase-like protein", "aln": "MAFMEQQPQPLSGRKPPLDDTVPLSAVIEASQSLQSHTEYIIRVQRGVSTDNSWTVIRRYSDFDMLNNSLLISGLNLPLPPKKLLGNMDREFIAERQKGLQAYLNYITQHHILCSCELVKKFLDTNNYSANYTEIALQQVSMFFRSDPKWEVIEPLKDIGWRLRKRYFLVKDKD---------------------------------------QPKEKQVLSWVDLGPDKFLSDKDLQSAMKLLPTLSHSNISPVSFATTSESSALIIRVFSEKGTLRDHICKVK-PKEPFLRKYCNPKKIQGLELQQIRTFGRQILEALKFLHDKGFPYGHLHASNVLIEENTCKLLDVENSLLGLPSYYRPYVTQFRKINTTESIDVYSFGHLLYEMTYGRPPDAVPVDQCPPAPFSSIVSVLQSILSTEACKTGMPTVSQLLQTPLFYDVLLFN-------SEKPQFKISSKLKEALKSSKEGLEKRLVEEQRTIHQHKRLTRAQSHHGSEEEKRKRKILARKKSRQSTYEIEEDLSVKYN--NNSAGSGASSPPTC-------------PSSPTPLPGSGAP--LPPPPPPPPPP--------PPPGIDSG------PPSLSPPSANGVG----RGALLSSIQSFSKNKLKKAETVDRSGPRL-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z782-1", "uniprot_id": "A1Z782_DROME", "id": "A1Z782-1", "name": "PX domain-containing protein kinase-like protein", "aln": "MAVFASRY----ERKLPIDDTQALSCEITAVQEVAGHTEYLLRVWRGASNKNYWTVLRRYNDFDRLDKSLRVSGIELPLPRKRIFGNMRPEFIAERKQALQEYINAVLMNPILASSLPAKRFVDPESYSQSFHDHAVQNAMLCLRNDTTWSLGGSMGAIGWRLRKHYFKVTTKPPEKSSNKQLVKSGSQTHQSKHFAAGSSNGSGHSIDAGTLDPGSEVVAEWLEYGPDKFIDEKEIGGIMKSLMGLQHPHIEPVLLAAHTENGCLVIRKFHKHGTLKDVLCMAANPKNTFLSKYGNPKGRTALSMKQVATYGKQILEALIFLHSKGYAYGHLHSGNIVIVDDCVKLLDIENFLLGVPAFYRPFFMQHSKIHAIETIDVYCFGHVLFEMAMGYPLQESVVRQITECP-EALKCLLESILSKEACKAGLPTLEQLLGHRFFLQYASTESAGAAANAEKPYFKLSLNAKELLKQAAIKSENRLRDEQKSVKNQKRIVRVQELMSSEEEKRKSKQKAKLEHKQSKLKQQSSIQTNNGRLSLVAATAAAASSSTTVVGELCGTDSFNRSDSTPEEPTTLAGIKSPPLTPGPHLGSIYQQELPSTTGAPVERQSSTPNMLSEDAEGGDGDEPTRSALLESICKFNRGSLRKVRSND-------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.: . * :*** .*:. : * *.: .****::** ** * .* * ::***.*** *::** ::*:.**** *:::*** ******::.** *:* : : :*... *:*:*.:.** .: : *:*:. : :*.:..*.: .: ****:**:** :. * :* .. * .* : ****::.:*:: :* * *. * * :*: .*...*:** * .:***:* : . **:.** ** *** .*.::*: *:*:****.* ***.**:.*****:.*::: : :***:** ***:*::**.:. *. **:: *::**:.***:*:**: * * : * . . .. :: .:*:* ** **** *:**:.:** :* : :*** **:. : :* *: : *:** :**: :::::*:.*.*. .****::: * *: : ::* : ... .: . . *.:.*::. : *..** : . .** .* * ... . * . .* . *.***.** .*.:..*:*..: * ", "identical_positions": 202, "similar_positions": 205, "identity": "30.7%" }, { "cls_id": "homologset.agr.MGI:1289231", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q05310-1", "uniprot_id": "L10K_RAT", "id": "Q05310-1", "name": "Leydig cell tumor 10 kDa protein", "aln": "MAQGQRKFQAQKP-KSK--AAAAERSRGPRKGGRV-IGPKKARVVQQQKLKKSLEVGIRKKIEHDVVMKASSSLPKKLALLKGASKK---TGAT-PGKTPS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R1F0-1", "uniprot_id": "L10K_MOUSE", "id": "Q8R1F0-1", "name": "Leydig cell tumor 10 kDa protein homolog", "aln": "MAQGQRKFQAQKP-KSK--AAAAERSRGPRKGGRV-IAPKKARVVQQQKLKKSLEVGIRKKIEHDVVMKASSSLPKRLALLKGASKK---SEATIPGKTPS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UNZ5-1", "uniprot_id": "L10K_HUMAN", "id": "Q9UNZ5-1", "name": "Leydig cell tumor 10 kDa protein homolog", "aln": "MAQGQRKFQAHKPAKSKTAAAASEKNRGPRKGGRV-IAPKKARVVQQQKLKKNLEVGIRKKIEHDVVMKASSSLPKKLALLKAPAKKK-GAAAATSSKTPS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q24JV4-1", "uniprot_id": "U390_DANRE", "id": "Q24JV4-1", "name": "UPF0390 protein zgc136864", "aln": "MAQGKQKFKAQRPGGAK---KHQNKPKGLKKGGRI-IAPKKAQVVQQQKLKKGLEVAIRNKIEHEVTQKASTSLHKKLSVLKTPAQKSGTAGAPKPAAGPSK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q3E747-1", "uniprot_id": "YL363_YEAST", "id": "Q3E747-1", "name": "Uncharacterized protein YLR363W-A", "aln": "MPQKPLKVTKKAK-DPR---RVTKKQKNLRKAAPLQLKSKKKSLQHLKKLKK--SSSLTETTERLVASKVG-----HLELLRGTRKEL--EKGKKNSK----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.* *. : .: :: :. :*.. : : .** : : :**** . .: :. *: *. *.. :* :*: . :: . . ", "identical_positions": 15, "similar_positions": 35, "identity": "14.71%" }, { "cls_id": "homologset.agr.MGI:1289234", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BWR8-1", "uniprot_id": "RHPN2_MOUSE", "id": "Q8BWR8-1", "name": "Rhophilin-2", "aln": "---MTDTLLPAAPQPLEKEGDDYFRKGCNPLAQTGRSKLQNQRAALNQQILKAVRMRTGAENLLKVATNQKVREQVRLELSFVNSDLQMLKEELEGLNISVGVYQGTEEAFTIPLIPLGLKETKEVDFSIVFKDFILEHYSEDSYLYEDDIADLMDLRQACRTPSRDEAGVELLMSYFIQLGFVESRFFPPTRHMGLLFTWYDSFTGVPVSQQTLLLEKASVLFNIGALYTQIGTRCNRQTQAGLESAVDAFQRAAGVLNYLKETFTHTPSYDMSPAMLSVLVKMMLAQAQESVFEKVCLPGIQNEFFVLVKVAQEAAKVAEAYRQLHAAMSQEPVKENIPYSWASVAYVKAYHYGALAHYFAATLLIDHQLKPGADEDHQEKCLSQLYDRMPEGMTPLATLKNAGQRVLLGKGHLHRAIGFHEESLREANLCKKLRDIQVLRDVLSAAHQRTQLKHTQHREDDDLLNLIDAPDVLPKTEREVKITFPDFSKVTVTDFFQKLGPLSVFSASKRWSPPRGIHFTVEEGDLGFTLRGNTPVQVHFLDPHCSASLAGAKEGDYIVSIQGVDCKWLTVSEVMKLLKSFGGEEVEMKVVSLLDSTS-SMHNKCATYSVGMQKTYSMICLSMDDDDKADKTKKISKKLSFLSWGTSKNRQKSASTLCLPEVGLARSQNKKKLPTPFSLLNSDSSLY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A8N7-1", "uniprot_id": "D4A8N7_RAT", "id": "D4A8N7-1", "name": "Rhophilin-2", "aln": "MASMTDALLPAAPQPLEKESDDYFRKGCNPLAQTGRSKLQNQRAALNQQILKAVRMRTGAENLLKVTTNQKVREQVRLELSFVNSDLQMLKEELEGLNISVGVYQGTEEAFTIPLIPLGLKETKEVDFSIVFKDFILEHYSEDSYLYEDDIADLMDLRQACRTPSRDEAGVELLMSYFIQLGFVESRFFPPTRHMGLLFTWYDSFTGVPVSQQTLLLEKASILFNIGALYTQIGTRCNRQTEAGLESAVDAFQRAAGVLNYLKETFTHTPSYDMSPAMLSVLVKMMLAQAQESVFEKICLLGIQNEFFVLVKVAQEAAKVAAAYRQLHAAMSQEPVKENIPYSWASVAYVKAYHYGALAHYFAATLLIDHQLKPGADEDHQEKCLSQLYDRMPEGMTPLATLKNDGQRVLLGKGHLHRAIDYHKESLREANLCKKLRDIQVLRDVLSAAHQRTQLKYTQHQQDDDLLNLIDAPDVLPKTEREVKITFPDFSKVTVTDFFQKLGPLSVFSASKRWSPPRGIHFRVEEGDLGFTLRGNTPVQVHFLDPHCSASLAGAKEGDYIVSIQGLDCKWLTVSEVMKLLKSFGGEEVEMKVVSLLDSTS-SMHNKCATYSVGMQKTYSMICLSMDDDDKADKTKKISKKPSFLSWSTSKNRQKSASTLCLPNVGLARPQNKKKLPTPFSLLNSDSSLY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8IUC4-1", "uniprot_id": "RHPN2_HUMAN", "id": "Q8IUC4-1", "name": "Rhophilin-2", "aln": "---MTDALLPAAPQPLEKENDGYFRKGCNPLAQTGRSKLQNQRAALNQQILKAVRMRTGAENLLKVATNSKVREQVRLELSFVNSDLQMLKEELEGLNISVGVYQNTEEAFTIPLIPLGLKETKDVDFAVVLKDFILEHYSEDGYLYEDEIADLMDLRQACRTPSRDEAGVELLMTYFIQLGFVESRFFPPTRQMGLLFTWYDSLTGVPVSQQNLLLEKASVLFNTGALYTQIGTRCDRQTQAGLESAIDAFQRAAGVLNYLKDTFTHTPSYDMSPAMLSVLVKMMLAQAQESVFEKISLPGIRNEFFMLVKVAQEAAKVGEVYQQLHAAMSQAPVKENIPYSWASLACVKAHHYAALAHYFTAILLIDHQVKPGTDLDHQEKCLSQLYDHMPEGLTPLATLKNDQQRRQLGKSHLRRAMAHHEESVREASLCKKLRSIEVLQKVLCAAQERSRLTYAQHQEEDDLLNLIDAPSVVAKTEQEVDIILPQFSKLTVTDFFQKLGPLSVFSANKRWTPPRSIRFTAEEGDLGFTLRGNAPVQVHFLDPYCSASVAGAREGDYIVSIQLVDCKWLTLSEVMKLLKSFGEDEIEMKVVSLLDSTS-SMHNKSATYSVGMQKTYSMICLAIDDDDKTDKTKKISKKLSFLSWGTNKNRQKSASTLCLPSVGAARPQVKKKLPSPFSLLNSDSSWY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A8MT19-1", "uniprot_id": "RHN2P_HUMAN", "id": "A8MT19-1", "name": "Putative rhophilin-2-like protein RHPN2P1", "aln": "----------------------------------------------------------------------------------------MLKEELEGLNISVGIYQNTEEAFTVPLIPLGLKETKDIDFSVILKDFILEHYSEDGYLYEDEITDLMDPRQACRTPSRDEARVELLMTYFIQLGFAWIRFKKYNTSPRIFFYRYDSLNGVLVSQQNLLLEKASVLFNTGALYTQIGTWRYWQMQAGLQSAIDAFQRAAGVLNYLKETFTHTPSYDMSPAMLSVLVKMMLTQAQESVFEKISLPGIRNEFFMLVKVAQEAAKVGEVYQQLHAAMSQALVKENIPYSWASLACVKAHHYTALAHYFTAILLIDHQVKPGMDLDHQEKCLSQLYDHMPEGLTPLATLKNDQQRRQLGKSHLHRAMAHHEESVREASLCKKLRSIEVLQKVLCAAQERSRLTYAQHQEDDDLLNLIHAPSVVAKTEQEP------------------KGPLSVFLANKQWMPPRSNRFTAEEGDLGFTLRGNAPVEVHFLDPYCSALVAGARGGDYIVSIQLVDCKWLTVSEVMKLLKSFGEDEIEMKVVSLLDSTS-SMHNKSATYSVGMQKTYSMICLAIDDDNKTDKTQKISKKLSFLSWGTNKNRQKSASTLCLPSVGAARPQVKKKLPSPFSLLNSDSSSY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6TNR1-1", "uniprot_id": "RHPN2_DANRE", "id": "Q6TNR1-1", "name": "Rhophilin-2", "aln": "---MTDTLIPNGCKSNGPVENGYFKKGCNPFAQTGRSKLQNKRAVLNQKIIKQMRMRAGAENLLKATSNNKVREQVVLELSYVNSDLQLLMEQLEGLNSSVEVYQNVQESSSIPLIPLGLKETKDVDFSVPLKDFILEHYSEDGSNFQNQIDDLMDLRQACRTPSRNNSGVDLIANYFSQLSFLETRFFSPTRQIGIFFTWYDSFTGMPVCQNNISLEKASMLFNMAALYSQIGTRADRQTLAGLEDAIAAFQKSARVLHFLKETFTHTPSYDMSPAMLSMLLRLMLAQAHECLFEQITLPGIRNEFFCLLKMAQEAAKVAETYAQVHQSMIETPITKNVPFFWTTMSQLKINHYNSLAHYFVSTALLDHQLNPSDDEDKQEKALSQLYDAMPEGRSPLDILKNKDERRRIGKAHLQRSIMGHEEAIRTHCRCRHLQKLDILSDILRASLNRSLTKFEQNDKEDEFTDYMLAPDIISKTEKKAEMEIPAATKVKVTDLFQRLGPLSVFSAKQRWTAPRTIRLILQDRDLGFTLKGDAPVQIQSLDPLCPAAAGGLKEGDYLVAVGDTDCKWMGVSDVMKLLKDVDEEGINIRVVSMMDSSSQPMATKSATYCGGLSKTYSMICLAHDEDDKNPKSRKVAKKPSFLSFGLKN--KKSSSTLSLPNADYSRPWNRP--SANYSNSHHESGLY", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* *:***** ** :**..:*: ::***********::**:: :***********. ::::* **** *********::: *:*: .** **.* ** . ::* ***:.*: *.*:.: *****:*** .***:**** * ***:.*: ***::* **::**:****************:*:::**:**:*.:**:: * **:**** *:*:*******. .* *:* :* : :.:*:*: *:::: :* ** :*****.: *:***::*. * *:***.****** **** :** *** :* :**.**:*:: *:*::* *::*:.:::* .:* *: :*: .. *: ::*:: : : **.::.***:: ****** *.::* .** :: :: ******:*::**::: *** *.* .* : ***:*:: ****: :*:******... : ::::***::**:* .* .*.***. *:.********: *:*:* *::*::** ****:. .: :**:***.**... :*. : .: :* : :*. *", "identical_positions": 278, "similar_positions": 187, "identity": "40.29%" }, { "cls_id": "homologset.agr.MGI:1289238", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZIL6-1", "uniprot_id": "D3ZIL6_RAT", "id": "D3ZIL6-1", "name": "", "aln": "MLRALPRAL----RLRRPWMSPGARGCAAHASTRTP-EIQVQALTGPNQGITEILMNRPHARNALGNVFVSELLEALAQLREDQQVRVLLFRSAVKGVFCAGADLKERERMSAAEVGTFVQRLRGLMSEIAAFPAPTIAAMDGFALGGGLELALACDLRIAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLNGVQAHELGLVNHAVAQNEEGDAAYHRALALAQEILPQAPIAVRLGKVAIDRGMEVDIASGMAIEHMCYAQNIPTQDRLEGMAAFREKRPPKFVGK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3TLP5-1", "uniprot_id": "ECHD2_MOUSE", "id": "Q3TLP5-1", "name": "Enoyl-CoA hydratase domain-containing protein 2, mitochondrial", "aln": "MLRVLPRAL----RLPCSWRFSGARDCASHATTRTP-EIQVQALTGPNQGITEILMNRPNARNALGNVFVSELLEALAQLREDQQVRVLLFRSAVKGVFCAGADLKEREQMSDVEVGTFVQRLRGLMSEIAAFPVPTIAAMDGFALGGGLELALACDLRIAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLNGAQARELGLVNHAVAQNEEGNAAYHRALALAQEILPQAPIAVRLGKVAIDRGMEVDIASGMAIEQMCYAQNIPTQDRLEGMAAFREKRAPKFVGK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86YB7-1", "uniprot_id": "ECHD2_HUMAN", "id": "Q86YB7-1", "name": "Enoyl-CoA hydratase domain-containing protein 2, mitochondrial", "aln": "MLRVL--------CLLRPWRPLRARGCASDGAAGGS-EIQVRALAGPDQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQMSEAEVGVFVQRLRGLMNDIAAFPAPTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGTEAHVLGLVNHAVAQNEEGDAAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMAAFREKRTPKFVGK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PM54-1", "uniprot_id": "A0A8M1PM54_DANRE", "id": "A0A8M1PM54-1", "name": "", "aln": "MAAARGVFAGPIKRLLPRGSFTQTRSWCSNGSVSDKKEVRLNRLEGEDNGIVEVLMCRERARNSLGHVFVGQMRDLVSSLQHDSAVRVLVFRSLIPGVFCAGADLKERAQMSNAEAELFVHGLRSLMNDIAALPMPTIAAVDGFALGGGLELALACDLRTAAHCAQMGLIETTRGLLPGAGGSQRLPRTVGFAVAKELIFTGRRVGGEQAVNLGLVNRSVPQNQTGDAAHREALSLAREILPQAPIAVRMAKVAMNRGAEVDISSGMAIEGMCYARLIPTRDRQEGMAAFIEKRPPRYTGE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z934-1", "uniprot_id": "A1Z934_DROME", "id": "A1Z934-1", "name": "Methylglutaconyl-CoA hydratase, mitochondrial", "aln": "MSMLIKRASGLARQLARP--LVASRNLASAAPYGDGTEVLVERLDGARQGISVIGLNRPAAKNSFSRGMVETFNDVLEDIKKDNGSRVVVLRSLSPGIFCAGADLKERKGMTPEEATEFVKELRGLLIAIEQLPMPVIAAVDGAALGGGLEMALACDIRTAASDTKMGLVETRLAIIPGAGGTQRLPRILSPALAKELIFTARVFNGAEAKDLGLVNHVVKQNETQDAAYQQALKLAEEILPNGPVGVRMAKLAIDKGMQVDLATGYSIEEICYSQVIPTKDRLEGLAAFAEKRKPVYKGE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * :*. .: .. *: :. * * :** : : * *:*::.. :* : : : .::.* **:::** *:********** *: *. **: **.*: * :* *.***:** *******:*****:* ** : ***:** .::*****:***** :. *:*******.* ..* :* *****: * **: :**::.* **.****:.*:.**:.*:*:::* :**:::* :** :**:: ***:** **:*** *** * : *:", "identical_positions": 129, "similar_positions": 81, "identity": "42.86%" }, { "cls_id": "homologset.agr.MGI:1289247", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JVJ7-1", "uniprot_id": "A0A0G2JVJ7_RAT", "id": "A0A0G2JVJ7-1", "name": "", "aln": "-MEAADYEVLSVREQLFHDRVRECIISILLFATLYILCHIFLTRFKKP--AEFTTVDDEDATVNKIALELCTFTLAVALGAVLLLPFSIISNEVLLSLPRNYYIQWLNGSLIHGLWNLVFLFSNLSLVFLMPFAYFFTESEGFAGSRKGVLGRVYETVVMLILLTLLVLGMVWVASAIVDNDKASRESLYDFWEYYLPYLYSCISFLGVLLLLVCTPLGLARMFSVTGKLLVKPRLLEDLEEQLNCSAFEEAALTRRICNPTSC------------------------------------------WLPLDMELLHRQVLALQAQRVLLEKRRKASAWQRNLGYPLAMLCLLVLTGLSVLIVAVHILELLIDEAAMPRGMQDAALGQVSFSKLGSFGAIIQVVLIFYLMVSSVVGFYSSPLFGSLRPRWHDTSMTQIIGNCVCLLVLSSALPVFSRTLGLTRFDLLGDFGRFNWLGNFYIVFLYNAAFAGLTTLCLVKTFTAAVRAELIRAFGLDRLPLPVSG------FPRGSRKKQHQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D1E5-1", "uniprot_id": "LMBRL_MOUSE", "id": "Q9D1E5-1", "name": "Protein LMBR1L", "aln": "-MEAADYEVLSVREQLFHDRVRECIISILLFATLYILCHIFLTRFKKP--AEFTTVDDEDATVNKIALELCTFTLAVALGAVLLLPFSIISNEVLLSLPRNYYIQWLNGSLIHGLWNLVFLFSNLSLVFLMPFAYFFTESEGFAGSRKGVLGRVYETVVMLILLTLLVLGMVWVASAIVDNDKASRESLYDFWEYYLPYLYSCISFLGVLLLLVCTPLGLARMFSVTGKLLVKPRLLEDLEEQLNCSAFEEAALTRRICNPTSC------------------------------------------WLPLDMELLHRQVLALQAQRVLLEKRRKASAWQRNLGYPLAMLCLLVLTGLSVLIVAVHILELLIDEAAMPRGMQDAALGQASFSKLGSFGAIIQVVLIFYLMVSSVVGFYSSPLFGSLRPRWHDTSMTQIIGNCVCLLVLSSALPVFSRTLGLTRFDLLGDFGRFNWLGNFYIVFLYNAAFAGLTTLCLVKTFTAAVRAELIRAFGLDRLPLPVSG------FPRASRKKQHQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6UX01-1", "uniprot_id": "LMBRL_HUMAN", "id": "Q6UX01-1", "name": "Protein LMBR1L", "aln": "-MEAPDYEVLSVREQLFHERIRECIISTLLFATLYILCHIFLTRFKKP--AEFTTVDDEDATVNKIALELCTFTLAIALGAVLLLPFSIISNEVLLSLPRNYYIQWLNGSLIHGLWNLVFLFSNLSLIFLMPFAYFFTESEGFAGSRKGVLGRVYETVVMLMLLTLLVLGMVWVASAIVDKNKANRESLYDFWEYYLPYLYSCISFLGVLLLLVCTPLGLARMFSVTGKLLVKPRLLEDLEEQLYCSAFEEAALTRRICNPTSC------------------------------------------WLPLDMELLHRQVLALQTQRVLLEKRRKASAWQRNLGYPLAMLCLLVLTGLSVLIVAIHILELLIDEAAMPRGMQGTSLGQVSFSKLGSFGAVIQVVLIFYLMVSSVVGFYSSPLFRSLRPRWHDTAMTQIIGNCVCLLVLSSALPVFSRTLGLTRFDLLGDFGRFNWLGNFYIVFLYNAAFAGLTTLCLVKTFTAAVRAELIRAFGLDRLPLPVSG------FPQASRKTQHQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q803C7-1", "uniprot_id": "LMBRL_DANRE", "id": "Q803C7-1", "name": "Limb region 1 homolog-like protein", "aln": "-METED---VTVREQIFHDRVRETIICVLLFICLYILSHFILTHFKKS--AEFVTDDIEDATVNKIALWLCTFTLSVAVCAVLLLPISILSNEVLLTFPHSYYMQWLNGSLIRGLWNLVFLFSNLSLVFLMPFAYFFTESEGFAGSKKGVMARVYETAVMLLLLSLLVLGIVWVASALLHHN-TARESLYDLWEYYLPYLYSGISLFGVLLLLLCTPFGLSRMFSVTGSLLVKPRLLENLEETMNCAVFEEASLSRKLKSTNTC------------------------------------------WISAHLEALNKEFLSVQSKRITLELRKRASPWQRNLVYPVAMLLLLALTAVSVLMVCFHVLELLFDESAMPRGMEDPHLGLASFSMLGSLGAAVQVVIILYLMVSSVVGFYSSPLFTGLLPRAQDTTLTQIIGNCVSLLILSSALPVFSRTLGITKFDLLGDFGRHDWLGSFHIVFLYNMLFAGLTSACLINTVTWALQRELIRAFGLHRLPLTVSRSTIPLKLLLANGLSKIH", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VC35-1", "uniprot_id": "LILI_DROME", "id": "Q9VC35-1", "name": "Protein Lilipod", "aln": "MDEEEEEEVTDLKLQLFHNTVREHIIFLLLIILLYSSSYVVVSRFRRRDRDDLYSNDEDEVLVYRISFWLCTFTLAVAEGAAMLLPVSIASNEVLLLYPNSYYVKWLNSSLIQGLWNHVFLFSNLSLFIFLPFVYLFSESTGFVGNKKGILPRVYETFTVFMLMAIIVLVLTAVLSAVFGIEKLQFFWFLNLGSVHLPFLYSCVSFLGVMLMLICTPYGFVRLFGVVNQVLVRPMLLRDVNEEFSAFYMEEASVKRKLAHIELHNVSIADAANGGRLGNRIGLGRGRTFYPQPLLQHSQAHLYQRKAMASDVDELNDRLRELDSERKELDKLRTSSTFQRTFVYPLAMLLLLFCTAVTILLVVQNTLELLIGIKALPLSTRQFALGISSLSKLGPFGAGLEVCLIFYLGATSVVGFYSMPFMRKVCPKRRQTSLPQLMLNCGFMLVLSSALPLLSRIIGITNFDLLGDFGAIEWLGNFQIVLLYNLVFGTTTALCLANKFTATVRRELRARLVEN-------------YVLFTNYISFIN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : :: *:**: :** ** **: ** .:..:::*:: :: : * ::. * :*:: ******::* *.:***.** ****** *..**::***.***:**** *********.:::**.*:*:** **.*.:**:: ***** .:::*::::** :. * **:. : : :: . :**:*** :*::**:*:*:*** *: *:*.*...:**:* **.:::* : . :***::.*:: :. .:: *: .. ::::* *: : :*.:**.: **:*** ** *.:::*:* : ****:. *:* . . ** *:* **.:** ::* :*:** .:******* *:: : *: ::*::.*:: ** :*:******::** :*:*.******** :***.* **:*** *. *: ** :..* ::: ** : . . . . :", "identical_positions": 188, "similar_positions": 168, "identity": "34.81%" }, { "cls_id": "homologset.agr.MGI:1289248", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9BRA2-1", "uniprot_id": "TXD17_HUMAN", "id": "Q9BRA2-1", "name": "Thioredoxin domain-containing protein 17", "aln": "MARYEEVSVSGFEEFHRAVEQHNG--KTIFAYFTGSKDAGGKSWCPDCVQAEPVVREGLK-HISEGCVFIYCQVGEKPYWKDPNNDFRK--NLKVTAVPTLLKYGTPQKLVESECLQANLVEMLFSED----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9CQM5-1", "uniprot_id": "TXD17_MOUSE", "id": "Q9CQM5-1", "name": "Thioredoxin domain-containing protein 17", "aln": "MATFEEVSVLGFEEFDKAVKEHEG--KTIFAYFSGSKDTEGKSWCPDCVEAEPVIREGLK-HVTEDCVFIYCQVGDKPYWKDPNNDFRQ--KLKITAVPTLLKYGTPQKLVESECCQSSLVEMIFSED----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6DBT3-1", "uniprot_id": "TXD17_DANRE", "id": "Q6DBT3-1", "name": "Thioredoxin domain-containing protein 17", "aln": "MSKYEEVAVHGYEEFCKAVSDRKG--KEIFAYFSGDKDEHGKSWCPDCVKAEPVVRAELP-HLPEGTVFIYCQVGDRPYWKDSNNDFKK--TLKLTGVPTLLRYGTPQKLVEEECFKADLVRMMFTED----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VMQ9-1", "uniprot_id": "Q9VMQ9_DROME", "id": "Q9VMQ9-1", "name": "Thioredoxin domain-containing protein 17", "aln": "--MVVTHNVKGYDEFTKKMEELENGDEPVHVLFSGGKDEKGESWCPYCVKAEPVIHDALK-KAPGNSHFVHVDVGERAYWKDLNCPFRKDPNTHLIFLPTLLRWKRPQRLDGERCSNQDLVEMMFEDED---------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9U1K7-1", "uniprot_id": "Q9U1K7_DROME", "id": "Q9U1K7-1", "name": "Thioredoxin domain-containing protein 17", "aln": "--MPEYVPARGFKEMENLIKLYENQRSPIYIYFYGEKDKDGRSWCPDCVAAEETIMSAFRNHAPADCMILVVDVGSRESWIGKDNMFRK-PPYSVEGIPTLIRWKGVERLDGDQLLKSSLLELFFEETDPKKSNFVAQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *:.*: . :. :. . :. * * ** *.**** ** ** .: : : . . :: :**.: * . : *:: : :***::: ::* .. : .*:.::* : ", "identical_positions": 25, "similar_positions": 44, "identity": "18.12%" }, { "cls_id": "homologset.agr.MGI:1289252", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q925E7-1", "uniprot_id": "2ABD_MOUSE", "id": "Q925E7-1", "name": "Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform", "aln": "-----------------------------------------------MAGAGGGGCPAGGNDFQWCFSQVKG-AVDEDVAEADIISTVEFNYSGDLLATGDKGGRVVIFQREQENKGRAHSRGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLPQQNAAHFLLSTNDKTIKLWKISER----------------DKRAEGYNLKDEDGRLRDPFRITALRVPILKPMDLMVEASPRRIFANAHTYHINSISVNSDHETYLSADDLRINLWHLEITDRSFNIVDIKPANMEELTEVITAAEFHPHQCNVFVYSSSKGTIRLCDMRSSALCDRHAKFFEEPEDPSSRSFFSEIISSISDVKFSHSGRYMMTRDYLSVKVWDLNMEGRPVETHQVHEYLRSKLCSLYENDCIFDKFECCWNGSDSAIMTGSYNNFFRMFD------------------------------------------------RNTRRDVTLEASRENSKP------------------RASLKPRKVCTGGKRK--------KDEISVDSLDFNKKILHTAWHPMESIIAVAATNNLYIFQDKIN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P56932-1", "uniprot_id": "2ABD_RAT", "id": "P56932-1", "name": "Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform", "aln": "-----------------------------------------------MAGAGGGGCPTGGNDFQWCFSQVKG-AVDEDVAEADIISTVEFNYSGDLLATGDKGGRVVIFQREQENKGRAHSRGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLPQQNAAHFLLSTNDKTIKLWKISER----------------DKRAEGYNLKDEDGRLRDPFRITALRVPILKPMDLMVEASPRRIFANAHTYHINSISVNSDHETYLSADDLRINLWHLEITDRSFNIVDIKPANMEELTEVITAAEFHPHQCNVFVYSSSKGTIRLCDMRSSALCDRHAKFFEEPEDPSSRSFFSEIISSISDVKFSHSGRYMMTRDYLSVKVWDLNMEGRPVETHHVHEYLRSKLCSLYENDCIFDKFECCWNGSDSAIMTGSYNNFFRMFD------------------------------------------------RNTRRDVTLEASRENSKP------------------RASLKPRKVCSGGKRK--------KDEISVDSLDFNKKILHTAWHPMESIIAVAATNNLYIFQDKIN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q66LE6-1", "uniprot_id": "2ABD_HUMAN", "id": "Q66LE6-1", "name": "Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform", "aln": "-----------------------------------------------MAGAGGGGCPAGGNDFQWCFSQVKG-AIDEDVAEADIISTVEFNYSGDLLATGDKGGRVVIFQREQENKSRPHSRGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLPQQNAAHFLLSTNDKTIKLWKISER----------------DKRAEGYNLKDEDGRLRDPFRITALRVPILKPMDLMVEASPRRIFANAHTYHINSISVNSDHETYLSADDLRINLWHLEITDRSFNIVDIKPANMEELTEVITAAEFHPHQCNVFVYSSSKGTIRLCDMRSSALCDRHSKFFEEPEDPSSRSFFSEIISSISDVKFSHSGRYMMTRDYLSVKVWDLNMESRPVETHQVHEYLRSKLCSLYENDCIFDKFECCWNGSDSAIMTGSYNNFFRMFD------------------------------------------------RDTRRDVTLEASRESSKP------------------RASLKPRKVCTGGKRR--------KDEISVDSLDFNKKILHTAWHPVDNVIAVAATNNLYIFQDKIN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NY64-1", "uniprot_id": "2ABD_DANRE", "id": "Q6NY64-1", "name": "Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform", "aln": "-----------------------------------------------MAGVGGG------NDFQWCFSQVKG-AIDEDVAEADIISTVEFNYSGELLATGDKGGRVVIFQREQESKNRPLSRGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLPQQNAAHFLLSTNDKTIKLWKISER----------------DKRAEGYNLKDEDGRLRDPFRITSLRVPVLMPMDLMVEASPRRIFANAHTYHINSISVNSDYETYLSADDLRINLWHLEITDRSFNIVDIKPANMEELTEVITAAECHPHQCNVFVYSSSKGTIRLCDMRAAALCDRHSKFFEEPEDPSSRSFFSEIISSISDVKFSHSGRYMMTRDYLSVKVWDLNMENRPVETYQVHEYLRSKLCSLYENDCIFDKFECCWNGSDSAIMTGSYNNFFRMFD------------------------------------------------RNTRRDITLEASRESSKP------------------RAMLKPRKVCTGGKRK--------KDEISVDSLDFNKKILHTAWHPKENVIAVAATNNLYIFQDKMN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P36872-1", "uniprot_id": "2ABA_DROME", "id": "P36872-1", "name": "Protein phosphatase PP2A 55 kDa regulatory subunit", "aln": "MGRWGRQSPVLEPPDPQMQTTPPPPTLPPRTFMRQSSITKIGNMLNTAININGAKKPASNGEASWCFSQIKG-ALDDDVTDADIISCVEFNHDGELLATGDKGGRVVIFQRDPASKAANPRRGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLQQKNPVHFLLSTNDKTVKLWKVSER----------------DKSFGGYNTKEENGLIRDPQNVTALRVPSVKQIPLLVEASPRRTFANAHTYHINSISVNSDQETFLSADDLRINLWHLEVVNQSYNIVDIKPTNMEELTEVITAAEFHPTECNVFVYSSSKGTIRLCDMRSAALCDRHSKQFEEPENPTNRSFFSEIISSISDVKLSNSGRYMISRDYLSIKVWDLHMETKPIETYPVHEYLRAKLCSLYENDCIFDKFECCWNGKDSSIMTGSYNNFFRVFD------------------------------------------------RNSKKDVTLEASRDIIKP------------------KTVLKPRKVCTGGKRK--------KDEISVDCLDFNKKILHTAWHPEENIIAVAATNNLFIFQDKF-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q00362-1", "uniprot_id": "2ABA_YEAST", "id": "Q00362-1", "name": "Protein phosphatase PP2A regulatory subunit B", "aln": "---------------------------------------------------------MAQNNFDFKFSQCFGDKADIVVTEADLITAVEFDYTGNYLATGDKGGRVVLFER------SNSRHCEYKFLTEFQSHDAEFDYLKSLEIEEKINEIKWLRPTQRSHFLLSTNDKTIKLWKVYEKNIKLVSQNNLTEGVTFAKKGKPDNHNSRGGSVRAVLSLQSLKLPQLSQHDKIIAATPKRIYSNAHTYHINSISLNSDQETFLSADDLRINLWNLDIPDQSFNIVDIKPTNMEELTEVITSAEFHPQECNLFMYSSSKGTIKLCDMRQNSLCDNKTKTFEEYLDPINHNFFTEITSSISDIKFSPNGRYIASRDYLTVKIWDVNMDNKPLKTINIHEQLKERLSDTYENDAIFDKFEVNFSGDSSSVMTGSYNNNFMIYPNVVTSGDNDNGIVKTFDEHNAPNSNSNKNIHNSIQNKDSSSSGNSHKRRSNGRNTGMVGSSNSSRSSIAGGEGANSEDSGTEMNEIVLQADKTAFRNKRYGSLAQRSARNKDWGDDIDFKKNILHFSWHPRENSIAVAATNNLFIFSAL--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: .: *** * * *::**:*: ***:: *: ***********:*:* : **:. : ****:.***************:*:** : **********:****: *: * * :...* :* : :*::* : :: *:*:* ::***********:*** **:***********:*:: ::*:*******:**********:** ** :**:*:********:***** :***.::* *** :* .:.**:** *****:*:* .***: :****::*:**::*: :*::* :** *: :*.. ****.****** :.*..*::******* * :: *.. :: : .* : :. . *:. *.. .** ::: * :**:*:*** :*** :. *********:**. ", "identical_positions": 223, "similar_positions": 118, "identity": "37.73%" }, { "cls_id": "homologset.agr.MGI:1289257", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3ULJ0-1", "uniprot_id": "GPD1L_MOUSE", "id": "Q3ULJ0-1", "name": "Glycerol-3-phosphate dehydrogenase 1-like protein", "aln": "------------------------------------------------------------------------------MAAAPLKVCIVGSGNWGSAVAKIIGSN-VKTLQKFSSTVKMWVFEETVNGRKLTDIINNDHENVKYLPGHKLPENVVAVPNLSEAVQDADLLVFVIPHQFIHKICDEITGRVPEKALGITLIKGIDEGPDG-LKLISDIIREKMGIDISVLMGANIASEVAAEKFCETTIGSKVMQNG---------LLFKELLQTPNFRITVVDDADTVELCGALKNIVAVGAGFCDGLRCGDNTKAAVIRLGLMEMIAFAKIFCKG-QVSTATFL-ESCGVADLITTCYGGRNRRVAEAFARTGKTIEELEKELLNGQKLQGPQTSAEVYRILRQKGLLDKFPLFTAVYQICYEGRPVTQMLSCLQSHPEHI-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZAP9-1", "uniprot_id": "D3ZAP9_RAT", "id": "D3ZAP9-1", "name": "Glycerol-3-phosphate dehydrogenase [NAD(+)]", "aln": "------------------------------------------------------------------------------MAAAPLKVCIVGSGNWGSAVAKIIGSN-VKNLQKFSSTVKMWVFEETVNGRKLTDIINNDHENVKYLPGHKLPENVVAVPNLGEAVQDADLLVFVIPHQFIHKICDEITGRVPKKAVGITLIKGIDEGPDG-LKLISDIIREKMGIDISVLMGANIASEVAAEKFCETTIGSKVLQNG---------LLFKELLQTPNFRITVVDDADTVELCGALKNIVAVGAGFCDGLCCGDNTKAAVIRLGLMEMIAFAKIFCKG-QVSTATFL-ESCGVADLITTCYGGRNRKVAEAFARTGKTIEELEKELLNGQKLQGPQTSAEVYRILKQKGLLDKFPLFTAVYQICYEGRPVTQMLSCLQSHPEHI-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N335-1", "uniprot_id": "GPD1L_HUMAN", "id": "Q8N335-1", "name": "Glycerol-3-phosphate dehydrogenase 1-like protein", "aln": "------------------------------------------------------------------------------MAAAPLKVCIVGSGNWGSAVAKIIGNN-VKKLQKFASTVKMWVFEETVNGRKLTDIINNDHENVKYLPGHKLPENVVAMSNLSEAVQDADLLVFVIPHQFIHRICDEITGRVPKKALGITLIKGIDEGPEG-LKLISDIIREKMGIDISVLMGANIANEVAAEKFCETTIGSKVMENG---------LLFKELLQTPNFRITVVDDADTVELCGALKNIVAVGAGFCDGLRCGDNTKAAVIRLGLMEMIAFARIFCKG-QVSTATFL-ESCGVADLITTCYGGRNRRVAEAFARTGKTIEELEKEMLNGQKLQGPQTSAEVYRILKQKGLLDKFPLFTAVYQICYESRPVQEMLSCLQSHPEHT-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5XIZ6-1", "uniprot_id": "GPD1L_DANRE", "id": "Q5XIZ6-1", "name": "Glycerol-3-phosphate dehydrogenase 1-like protein", "aln": "-------------------------------------------------------------------------------MAAPLKVCIVGSGNWGSAIARIIGSN-AQKLQCFATTVKMWVYEEMVNGKKLSEIINTEHENVKYLPGYKLPENVVAVPQLRDAADGADLLVFVVPHQFIRKLCDEMMGCVSERARGITLIKGIDEGPEG-LKLISDIIREKMGIDVSVLMGANIANEVAAEKFCESTIGSKVLENG---------LLFKDLLQTPNFRITVVDDADTVELCGALKNIVAVGAGFCDGLQCGDNTKAAVIRLGLMEMIAFAKLFSKDDSVSSATFL-ESCGVADLITTCYGGRNRRVAEAFAKTGKSIEELEKEMLNGQKLQGPLTSAEVYHILKQKGLVEKFPLFTAVYQICFEDKPVRDMITCLQSHPEHL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P13706-3", "uniprot_id": "GPDA_DROME", "id": "P13706-3", "name": "Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic", "aln": "-------------------------------------------------------------------------------MADKVNVCIVGSGNWGSAIAKIVGAN-AAALPEFEERVTMFVYEELIDGKKLTEIINETHENVKYLKGHKLPPNVVAVPDLVEAAKNADILIFVVPHQFIPNFCKQLLGKIKPNAIAISLIKGFDKAEGGGIDLISHIITRHLKIPCAVLMGANLANEVAEGNFCETTIGCTDKKYG---------KVLRDLFQANHFRVVVVDDADAVEVCGALKNIVACGAGFVDGLKLGDNTKAAVIRLGLMEMIRFVDVFYPG--SKLSTFF-ESCGVADLITTCYGGRNRRVSEAFVTSGKTIEELEKEMLNGQKLQGPPTAEEVNYMLKNKGLEDKFPLFTAIHKICTNQLKPNDLIDCIRNHPEHMDTSIMPSPKL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8IN06-1", "uniprot_id": "Q8IN06_DROME", "id": "Q8IN06-1", "name": "Glycerol-3-phosphate dehydrogenase [NAD(+)]", "aln": "-------------------------------------------------------------------------------MAGKLKICIIGAEGWGSAIAAVVSNN-VLEG-DFDSRVHLYVYDEMIRDTALSEIINTRHENVKYLPGIKLPNNLIAVNDLLEAAQNADILVFSTPLEFVQSYCNILSGNVKESAFAVSMTKGLLSENGEGIELVSHAISESLGIPCYSMMSAHSAMEMAQGKLCEVTIGCSDNSHS---------KLLISAMQTNNCRVISVNDVDGVELCGTLTDVVALGAGFIDGLRLGENARLAAIHLGVKEIMRFIKTFFPS--SKMSTFY-ESCGVTNAVASSFVDKNVTFAKSLVTSGQTIEEIEANLHSGRKLLGPMVASNVNAFLENGLMQHEFPLFTAIHLICQSEAPPELMIEALRNHPDLSSSSISHLLNHERDELKTDQGLPELRTALDKILTEAGNENIKQLKVMDDWTEVNDYDVEETYHEKVASRDSCLETEIMPSRLSVQAAQLYNDIRDGNVGVAFKMDIDEGNRQVRLLLEKEDEMASDAALTVISSRLTAGQEDDNARIGHGHITNTSAESDHMSSKSIPSGLTTKDSPDVLDLSCESEPLHSSKQNSQLMEDAETNFTERLKVNQLKEQIDKQEAANFKAQENLIKSIRQTIQALGDKEKMENLIAKSKMEEDPFQLKSQVESSQLKSQVEGESSELKNQIQEEAYEPISQADEEPSQIRSQLDEESAQLKSLMDEENRQLESEMQDESSLLKSSADKSEFVAYNAEEEQPIEEPTDNHQYKLRSDTNKLKELMFTDSREHLESEKHIEVKLQDEHDFDLDEEPAIGKKDPTYTKENLELQERLEWQKLKQTDKPHHPYSSADLEDSTTNEGNARLPIEHDNRFQNVDRYQDRELVQVRAELKETSGAESEKEINLISEQRPDQNQDEVNLRPHSHIKTEETGHHEWDWLMNNEKIDSDEQKFYANERMETLSESDQDKLQNLNYQLKEALQHDLDVMSASRGNDSNEVLSEEDSNPEAAKKITEQPLNPTPNQIPAVPLPVTMPSKQSHIREGSPQFQNQPRSVPPPSPQTKPQSPKEQQPRRTNAPVEFGNKDEAMDLNESASDQEVPKRKKISKTEAVIEPVAKDVSMAEPNESLHSKKETSPASLSKQESKRKQKRSLRRPSSDSDSTKTTNEFEKQRQIIENQKAQLEKMGKKISVMRQGQDRRVSYKGHNPYSADPDLESRPPMDTSFEKDRTGDYQGLGHQRRKVVVAPPFHPPINPRVRVPRPPFDGRDHEFHTMTTAPVDRHLAPAAKWSSLPTTLKLNRNSLVANIQVKHFAALPCQALPKPILKLPMGVPRTPTFSKILCALQLGLLASYLACRKD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W1U3-1", "uniprot_id": "Q9W1U3_DROME", "id": "Q9W1U3-1", "name": "Glycerol-3-phosphate dehydrogenase [NAD(+)]", "aln": "--------------------------------------------------------------------------------MDKIMICIIGSGNWATTIARNVGRN-VLNSQTLDEKVPMYVYEEIVEGRKLTEIINTTHINSKYMPNFELPPNIVAVDDIVTTARDADIIIFAIPPTFVSSCCKTLLGKVKPTAHAVSLIKGFERGDDGQFVLISQIIMRQLKIPCSVLVGCNLAHELAHDHFAEGTVGCRDQKYY---------RVLHDIFKSPTFRVVVTEDADCVEICSTLRNIIAFAAGCSDGMELNENTKGGIIRRGFLEMLQFVDVFYPG--CRMGTFF-ESCGISDLVTSCYANRNRKLAEAFVKTGKPLSELEHILIPGHEPLGPVTAELVHHMLKKKGLEDKFPLFTTVYRICTGDYPLQRLVETLIKAREDIFHPLHTFQL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P41911-1", "uniprot_id": "GPD2_YEAST", "id": "P41911-1", "name": "Glycerol-3-phosphate dehydrogenase [NAD(+)] 2, mitochondrial", "aln": "MLAVRRLTRYTFLKRTHPVLYTRRAYKILPSRSTFLRRSLLQTQLHSKMTAHTNIKQHKHCHEDHPIRRSDSAVSIVHLKRAPFKVTVIGSGNWGTTIAKVIAENTELHSHIFEPEVRMWVFDEKIGDENLTDIINTRHQNVKYLPNIDLPHNLVADPDLLHSIKGADILVFNIPHQFLPNIVKQLQGHVAPHVRAISCLKGFELGSKG-VQLLSSYVTDELGIQCGALSGANLAPEVAKEHWSETTVAYQLPKDYQGDGKDVDHKILKLLFHRPYFHVNVIDDVAGISIAGALKNVVALACGFVEGMGWGNNASAAIQRLGLGEIIKFGRMFFPE--SKVETYYQESAGVADLITTCSGGRNVKVATYMAKTGKSALEAEKELLNGQSAQGIITCREVHEWLQTCELTQEFPLFEAVYQIVYNNVRMEDLPEMIEELDIDDE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q00055-1", "uniprot_id": "GPD1_YEAST", "id": "Q00055-1", "name": "Glycerol-3-phosphate dehydrogenase [NAD(+)] 1", "aln": "------------------------------------------------MSAAADRLNLTSGHLNAGRKRSSSSVSLKAAEK-PFKVTVIGSGNWGTTIAKVVAENCKGYPEVFAPIVQMWVFEEEINGEKLTEIINTRHQNVKYLPGITLPDNLVANPDLIDSVKDVDIIVFNIPHQFLPRICSQLKGHVDSHVRAISCLKGFEVGAKG-VQLLSSYITEELGIQCGALSGANIATEVAQEHWSETTVAYHIPKDFRGEGKDVDHKVLKALFHRPYFHVSVIEDVAGISICGALKNVVALGCGFVEGLGWGNNASAAIQRVGLGEIIRFGQMFFPE--SREETYYQESAGVADLITTCAGGRNVKVARLMATSGKDAWECEKELLNGQSAQGLITCKEVHEWLETCGSVEDFPLFEAVYQIVYNNYPMKNLPDMIEELDLHED------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : ::*: .*.:::* :. * : * ::*::* : . *::*** * * **: . ** *::* :: : ..*:::* * *: . : * : . .:: **: . *:* : : * : ..: * *:* : .* *:. . :: :: :: :*. :.:..:* :::* ..* :*: .:*: . : *. *:: * * *: **.*::: :::. .:* .: :. :*: * * : *:. * .. * *. ..**** ::: * : : . ", "identical_positions": 61, "similar_positions": 116, "identity": "4.37%" }, { "cls_id": "homologset.agr.MGI:1289258", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LN76-1", "uniprot_id": "F1LN76_RAT", "id": "F1LN76-1", "name": "Cilia- and flagella-associated protein 43", "aln": "MSQGRERD--------EASATVIPSASAHYSGASLSVRWVQGFPSQNVHFVNDNTICYPSGNYVIFINLETKKKTVLQCINGIVGVMATNVPGE----VVAFSDRRLKPIIYIYSFPSLTRKIKLKGDILLDYNLLCFSYCGTYLASYSSLPEFELALWNWEAN-VILCKKSNPGMDVSQMTFNPMNWRQMCLSSPSAVSVWTIERSNQEHHFRIRLVKLPQEDGTLSNETDMLFPTSLPKDLIYGPVLPLSAIAGLVGEEAETFRPKDDIYPLLHPTMHCWTPSSDLYVGCEEGHLLMINTETLKVTVLQKLEEFPVLDGAQLINP----LTLVYQKDGILASGIDGVIYSFIIKDTKYEVKPFLEFDGPVAHLAFSPSYKMLLIQTDKGSVYIYTFGTEPVLDKLLEACDGKVQAISFITPGNKYFLTLTSSGEVSIFSIEDGTCTGRIFLRTHATTLACSPSSSSAAMGTVDGSVYFLNILDVESPQLIHQAFLSKSPVKILIYDQRGIFLLVGTEEGKIFVIDARPSKSFQIFGYTESSKDMLQISTVSHVESDVVEVLVLSPLSETGRSRLEYFTLPIMLPQVVPENFA--DERGRLKDNFTHRYLYEVEHALSSAVLGFSESKIYGFCSQVPYICSYTMPV--KEHTGICILKPQQKVQSKQYGAGTIYLSSHGLWLITIAKCGVLCIRDMFSLDTFVRCRSHSHHGQGIQNMKMSMDGQHILVNGKDDNTLVYLKWKRLGSNIANEIFEHCHQLMLSLAKTVETECDYLASPDYQCVPPEEETTEFQKKLSLYSSQEELAID--LNKIPWIQRKMEEAVKKEVRIFTPRRKEIKRGIKELAQIIAAMMEENEKLDTIAKLDEQEFCLDAEELERLHDECEEEVSKIRKDVEMHNLAKSYLTELIKEECWNSMAVKGRALKCFHIPYVVDNFPMK---ERTEEELLELSKVIQQKKTEIECLKLRKEIVEAQSAATMVKKHHEEEEEEEEEDEEKVVKSTSLPNYLLGSLSTDFGADTSLLTNQLELHSREEKINQIILLKDIIYN-IKKTFNSEFDAAYKQKEIEIARVQEKNVRIAEIISDLELEEKVWQPVFEDSEKPERALVVEDDEISLQKYFAPWHK------TKA-ELLTAFDAERLQQARLSDARHRGLMDMMGGVLEVKKEDILRMVIPQPPFMSKPD-ALWSEEERKQFKEYEKKVKELNEERDKYRKSLEAELKKLQNAIQENTQNFDEHLKRLFERRVKAEMVINQEELKINNIVFSLLLDEELSSREQFLNNYLQKKQDEKTKTSEAIQKAREDLDVFKENHDTLVAEDKVLDRSFKKEFSDISGHQVDVLYKLFKRRPRVPKQKTQTEVNTLVPYGERPGSGKLNK-----ETFAQLMKSMDELDNVSNMPEGLDPSVWEHFCATRRAKVENEYKVKQKAACLLEMTTFLRKRMEDDDVVHHEIERVFHELVRLQDEKVKFQVNLTVQILLKQGQVELENFQLTLEYSDAILINKNIIEELNSVIRTQGQKKVASMMESKEVHKGIYQIEWEHKKMEMEMEDLNQKAWDIQMLFFSRDRQKYLN--EPNYEGVIAIQIGIMEQTISVIDKNHKKNVENCKKLLKKLGKCSNQKDVANYNLSCNLREELVAVSERQDICNEIGSKLTCEKIARERYDNLMKQQKLTNISKQQAEQISILQAEVERLRMKTFPALVPM-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q7R9-1", "uniprot_id": "CFA43_MOUSE", "id": "E9Q7R9-1", "name": "Cilia- and flagella-associated protein 43", "aln": "MSQDPERDDVTASATASASASAPASASAHYSGSSLSVRWVQGFPSQNVHFVNDQTICYPSGNFVIFINLETKKKTVLQCINGIVGVMATNVPSE----VVAFSDRRFKPVIYIYSFPSLTRKNKLKGDILLDYTLLCFSYCGTYLASYSSLPEFELALWNWEAS-AILCKKSNPGMDVSQMSFNPMNWHQMCLSSSSAMSVWTIERSNQEHHFRIRSVKLPLEDATFLNEPDMLFPTTLPKDLIYGPVLPLSAIAGLVGEEAETFRPKDDIYPLLHPTMHCWTPSSDLYVGCEEGHLLMINTETLKVTVLQKAEEFPLPDGAPLINP----LTLVYQKDGILASGIDGVIYSFIIKDSKYQVKTFLEFDGPVTHLVFSPSYKMLLIQTDKGSVYIYTFGAEMPLDKLLDACDGKVQAVSFITPGTKYFLTLTSSGEVSTVSLEDCNCTSRIFLKTQATALACSPSSPTAAVGTVDGYVYFLNILDVESPQMIHQAFLSQSPVKIVTYDQRGIFLLVGTEEGNIFVIDARPSKSFQIFGFTETGKDILQISTVSVMESDVVEVLVLYPLPDMGRSRLEYFTLPVMLPEVVPENFS--DERGRLKDDLTHKYLYEVEHTLSSAVLGFTGSKIFGFCSQVPYICSYVMPV--KEHTGVLVLKPHQKVQSKQYGSGTIYLSSHGLWLMTIAKCGILCIRDMFSMETFVRCRSHSHQGRGIQNMKMSLDGQHILVNGKDDNTLVCLKWKRLGANIASEIFEHSRPLVLHLSQTVESESVYLALSRESTNEQQEETTESQKHLNSDSSEEEAVID--HKMIPWIQQKMEEAIKKEVRIFSPRRKEIKRGIKELAQVIAMMMEENEKVDIIAKLDEQEFCLDADELERLHDECEEEVAKIRKDVEMHNLAQSYLTELIKEECWNSMAVKGRALKCFHIPYVVDNFPMK---ERTEEELQELSKVMQQKKTEIECLKLRKEIVEVQATTTIAKKHHEEEEEEEE-DEERTIKTTSLPNYLLGSLSTDFGADTSLLTSQLDLHSREEKINQIILLKDIIYN-IKRNFNSEFDAAYKQKEIEIARVKEKNVRIAEIISDLELEETVWQPVFEDSEKPERALVVEDDEISFKKYIAPWQR------AKIKEVVSTYEMERLQQARISDERQRGLMDMMGGVLEVKKEDILRMVIPQPPFMAKAD-ALWSEDERKQFKEYEKKVKELNEERDKYRKSLEAELKKLQNSIQESTQNFDDHLKRLFERRVKAEMVINQEELKINNIIFSLLLDEELSSREQFLNNYLLKKQEEKTKTAEAIQKAREDLDVFKEHHDMLVAEDKILDRSFKKEFSDILGHQVDVLYKLFKRRPRVHKQKTQADVTSLVPYGERPGSAKLNK-----ENLAQLMKSMDELDNINNMPEGLDPSVWEHFCSTRRAKVENEYKVKQKAACLLEMTTFLRKRMEEDDVVHHEIEKVFHELIRLQDEKVRFQVNLTVQILLKQGQVELENFQLMLEYSDAILINKNIIEDLNSVIRTQGQKKVASMMESKEVHKGIYQIEWEHKKMEMEMEDLNQRAWDIEMLFFSRDRQKYLN--EPNYENVIAIQIGIMEQTISVIDKTHKKNVENCKKLLKKLGKYSNQKDVANYTLSCNLREELVAVSERQDICNEIGSKLTCEKIARERYDNQLKQQKLLNISKQQAEQISILQAEVERLRMKTFPALIPM-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NDM7-1", "uniprot_id": "CFA43_HUMAN", "id": "Q8NDM7-1", "name": "Cilia- and flagella-associated protein 43", "aln": "MAQGRERD----------------EGPHSAGGASLSVRWVQGFPKQNVHFVNDNTICYPCGNYVIFINIETKKKTVLQCSNGIVGVMATNIPCE----VVAFSDRKLKPLIYVYSFPGLTRRTKLKGNILLDYTLLSFSYCGTYLASYSSLPEFELALWNWESS-IILCKKSQPGMDVNQMSFNPMNWRQLCLSSPSTVSVWTIERSNQEHCFRARSVKLPLEDGSFFNETDVVFPQSLPKDLIYGPVLPLSAIAGLVGKEAETFRPKDDLYPLLHPTMHCWTPTSDLYIGCEEGHLLMINGDTLQVTVLNKIEEESPLDRRNFISP----VTLVYQKEGVLASGIDGFVYSFIIKDRSYMIEDFLEIERPVEHMTFSPNYTVLLIQTDKGSVYIYTFGKEPTLNKVLDACDGKFQAIDFITPGTQYFMTLTYSGEICVWWLEDCACVSKIYLNTLATVLACCPSSLSAAVGTEDGSVYFISVYDKESPQVVHKAFLSESSVQHVVYDQQGIFLLVGTAEGKVFIINANSSSSFQIIGFTEVAKDILQISTVSLLETDIVEVMVLSSLPEAGRSRLEMFTLPTLLPQVS-TTFA--DERGRLKDEIIHKYLYELEHALSSAVLGFQSNQIYGFCSQVPYICSYLLPE--EEHTGIYILKPYKKVQSRQYGPGLLYLSSHGLWLITIAKCGILCIRDVYTLETFAWCRSHSHQGHGIQSMRISMDGQNILVNGRDDGTLVYLKWKRFGGHLASEILDYYQKLLISLSSAMDKENHYLSTTPKVSVDLGSDSEHTKQKASTDLSQDELVLTDVKKEIPWIQQKSQEAIKKEVNLFSKKRKEIKQGIKSLSKTILNMMEENDKLENIAKLDQQEFGLDLEELERLHDESQEEVAKMIKDVEMHNLAKSYLAELIKEECWNSMAVKGRALKCFHIPCVVENFPMK---ARTVEELKELERVLQQKKIEAECLKLRKEIVEAQSGVKLIKQRHEEDDEEEE-EEDKTVKYSNLPNYLLGSLSTDFGVDTSLLSSQLELHSREEKINQIILLKDIIYK-VKTVFNNEFDAAYKQKEFEIARVKERNVRIREIILDLELEEAVWQPEFEDCEKPERTLVVQDEEITAHKHIKPWH--------KAKELIVNHEKEHWLLIQDASTRLRALMDMMGGVLEVKKEDILRMVIPQPAFMAKPD-AVWTEEERKQFKDYEKKVKELNEERDKYRKSLEAELKKLQNSIQESTQAFDEHLKRLFERRVKAEMVTNQEELKISNLAFSLLLDEELSSREKFLNNYLTRKQHEKSQTSEAVRKSREDLDVCKEHYDNLLAEDKVMDRSFKKEFSEIPGHQVDILYKLFKRRPRISKQKTHSETTSVVPFGELPGSGKLNK-----DAFAQLMKAMDELDNISNMPEGLDPLVWNHFCMTRRAKVENEQKVKQKAADLLEMATFLQKRVEEEEKVQQEIERVFHELILLQEEKVRFQLNLTIQILLKQGQVELENFQLVLEYSDAILINKNIIEDLNSVIRTQGQKKVASMMESKDVHKRILQIEWEHKKMEMEREDLNQKAWDIQMLFFSRDRQKYLN--EPNYEALISIQIGIMEQTIAVLDKMHKKNVENCKKLLKKLGKFSNQKDIANYALSCNLREELVAVSERKDICNAMGSKLTCEKIVKERYENMMQQQKLTNISKQQAEQISILQTEVERLRMKTFPALVQM-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7TBN9-1", "uniprot_id": "A0A8N7TBN9_DANRE", "id": "A0A8N7TBN9-1", "name": "Cilia- and flagella-associated protein 43", "aln": "------------------------MVAEMDVLRNFEVQWVQGFTNGTFRFVDKKTVCYTCGNFIVFLNVETKERKTLQSPGSGIGAFTASGQRR----CIAFSDLGLKPSIFIYKYPELELTSELKGTTKLGYTALALCDTGPYLVSASPMPDHIITLWNWESG-LPLCSHSLLDEDISALVFNPMNWCQICAIKSKSLTIWNVERCDNYHLMKPSAVNLPGTDGSAIECEPNQSHLLNGKLTYLGPQMPTSAIAGLIGDQADNFVPLKLIKPRLCPSAICWSISSDLYVGCKEGFLLCVNPETLHVSVLYKPQTEVTTGNSEMPMQEGSFQSLVLQDSKLFAAGMESVLRSIQIKGNKLEVVQTWALEEAASAMCFSPDGETLLLTSNTGCVYRFKPLLKDKAVKVLDVLCGDFVTVAPVYTDRSICLSVREAGVVQLWTLDDGLCMGSISLQTHVTSMACCPIAQYIVVGTATGDVLFVEMTTKQKPRLVHRVHLYHVPVDHLVFDQGGNCLITGASDSRVFVLDSRPSKGFDIIGWIEAPGAIVGLSTQYHQESKQIKVLVLCNKSEKEISEGNVLLLLTLFAQQLTESTSCMDAHGCLRKEVFDSCVLELPNSLCSCVLAVN--KIFGYCQQRKVLQRFSIPENGENPNNVVQLIPEKETGGHLLSPAFLQLSPHHTWLASVGRDGLLRICEISEMDRYVQLQCHSCWQGGVGSVCFTPDSQTIITSGLRDGSLVCSRLKLSGVGKANAATQYSQSVADSFESVVSSENTVLTKMTDRDSFHTGEVS-LKGKMSHEAEQEENYFTS-PTSYTWLDGKLDAVLQEEAQQYAETKKNLRRNIKVLRDTIKAMMEENESLADIEKLEQQEFNLDVEEQQRLQLEGDQEVNRVRKEIEMENLAKSYQREVLKRECWDSMQVKGKAIKAFHSENEVKNYPMK---ERTAKELEELRMVENMRQIEQEDSQLQEGVLDTLFG-----------DKEEE------VSLTESP-ALTGSLSSLYGGVNPYLYNQFNLHVREQKINQITLLKDVIYN-VKSAFNKEFEAVYKQKEQEIHRTKEKNKRIFQIMAKLGISETLWEPRLTDNECPERALTVTDSEIKVEKYLTLEQK------EKEAKLREEEERQRLAAKSE-NMRDQGLSVMMGGVLELKKEDVLRMEVPQPEFMSKPE-AQWTEEERKSFKEFEKKAKELSEEQEKYRKTLETEMKKLLTSIKEATQMFDEKLAKLFERKVKSEMVIYQEELKIANLVLSIQTEEEILTREKQLSFKLEKARIKKNEIGEELKKHKETVDEFREAYDNTVAEDKLLDKGFRKEFYDVPGHSIDQLYKLYKRRPRVQRMKTQTENN---PFKEGAAPS---------DGLSLMMKAMEELDAPEHMLEGLDPAVWERFCLARRAKVESEQKVKLKALTLAEMQAFLQRRIDEDDEAQLEIKNLIDELNGLCDEKMRFRLDSMVQIVLQQGQVEVEAGEFIADYSNALLIQRKVVEDLNSTIRALGDQKIATMVECKDFRKGIIQQEWEHRRMRMQLEDLSNKARNIQTLRITQDIQDYLN--ETNNDNRVSKQLTTLERTLDLQKTAHQKKIEICKKQKRQLDRQVAKMQEKNAALDLRVAEMEITVAERRNFYEAAAMEDNQETESDKNYQDILLRKKLLAIARAQSEELLLLRAELEKLRMKNFPSLSQLHYN--------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VU57-1", "uniprot_id": "Q9VU57_DROME", "id": "Q9VU57-1", "name": "Cilia- and flagella-associated protein 43", "aln": "------------------------------MNITSTVCWCNIWDKDTLVNVGPDVLCQRNGNAMKFVHMQTKAVTFFKAETVSTGLSISCFAGHNRFPLFAFAEVVLRPNIYIYRYPDMAKFSSIP-PHMMSYTDIRFSELDLLIAVGG-YPDYCLCVFNYRTGTLVLEQFTNVPTVERGIVISFTSLPSIIQLNKQDMTIICYEICT----------------------VEKESFLYKVAEVELGKKFLKSCNRCLSFGEDNTLYATNDFGHLLSVDVACFALKPQWQPTSESDSVTEMEKMPRSHGLTYHKSGFLIWNS---------------TTAYYVKKKAGVFKLEWEFEGRLNEVVRFLSNNNGEIYAERRPGHIDQVVVDRNGTVSLEAVVPTGKPVITFRVVQG----------LKDECVCVLHDEGVAMMDLAKGNTLCEVSVPG-ATAMCNHRSLALVVVGTLDASIVLIHFERASLPHVLCDLKMETAAVVGIEFNDSWVVFQDQMKVLHVVQVDNRPHKLTHYFEMNPPELSQVFIHTFLLADGPRLMVFINRDHSMKR---------PGFATELWLYNWG--------KDKRLHRREYILP-------------KQYGFFCVQPPVGRWALIEIVATEYNTLNFDQFALNEKDELQWIASTKSGHFSYILGAGMTKHLVTWSLGGILVHFKQHKRAKKP------------------------FMICRFLNLGMQTEYILRVKECFNSKYLIILLANKSMRVMRLPSLADFVRENVALPLPTEEGIPCFVEQIIHKVDMFVPLSQR--QEVKEEYTRADLAKREKLFTIIKDFAAKVTALIDYDISKTGKTQGIFKKFCFHYRWLDALTEEAHKLCALERESLERAIADQSRIRDWILRLVTRDAVSINYRVRSIFADANFESFSVRRKVEMSEFDKYRFYDLEDHLRLSLGSFEEEEPPAPAAGGHGPPAAIEDGEVDEEETVEVVQGLRELKPFVVEGPSVYEHIMAPVFQLQDKNLVTSNQLFNYNCKIRFYLNDPLKQEFNKLFHEAQQLKQDTIDSVMNTNVVLNKIYDNMNIMLRLLN--MDQFKPPELTVPSLAKDEVIKQIMEVDDSEVKAINRRKPKTIDTGGKKGRLLLWSKEFWARALIVMMDGVLEKLWEEEIKKDIPEPEFMQKKQPHEFNLEEQKIFRAYEEAVHLLELDRRKYLRILHENEEKTLALKASQILKLNQRVAELMILKLKYDFALKQGQLRMLTLEKINFGRVQMRKRYNMFRKDIDKLNDYMTRYSNLLDFYDKAFLDVKTRLEAQQTRDRAVERQFRSQFLPLVPHATHEMTKLFKKRPKLPGKVFNSVLICMEASNKLSGKPSHRTPFPLPDDVLEFLNYLAEFDQPKQCPPNVDPKSWDAFVKLRRQKTESELRLKGIGYQLLDSQALLGVLNKDLAALKESKILTQRNSEDSIQTYLEKMRNMTIQLTLTMGQVEVSVMGQFTKLSNTVLMHVDDINDVNRQIQEAGNKKIKAMQRVAVFRRQVIFKEWEHKLYKANIAYLKYMLDAIEKCKVSMEFLNILRNWEKVKTERQKYIAGAIERVIEQKIAVFRKNIDRVNIKIDAVKAQTLEIKRSNHAIDFKIERIKVDVTFQNTLRDTMMED-KRDREQRERMSQIKTHRQLMENVRRNYAHVLELQTILELLRLRTYPTLGPPLPQCHPPVPEHILSSVP", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * * : : . .. *. ..:* ** : *::::** . ::. * : . .**:: ::* *::* :* : .: :.*. : :. . :. . *:. : ::*:.:. * . : : :. . .: . . ::: * . * : *. * : :.: . . : * *:: ..: .:.. : :: . : : . . . . . ::. : : *. :: .* * : . * . : : : : . : : .* :. .:** . : :: . . *::: : .* : ::: : .:. :: .. . . : : : * : : *:: . : .: . . :.. . : : :*: : : : . : * * :: . * .: : . : :: :: : * : : .: : : . * : . : : . :: .. :::: ** : : ::: : . : ::* :. : * * .: :.:* :* : : . . . ::.:. ...:.:: : : .: : : : . : .: . .*** * : *. . .: :* :: :* :: : . :* **. *. . : *: * . : * : :* .: : : : : : : ** :: .: .: : . : : : . :.* **.**** *: :: :*:* ** * : :. :*:* *: :*: .: *. :: ** : *. : :* . ::::: .*: ::* ::. * :*:: .: :: .* : : : : . .. .: : : . : : :.*: ::: *:.:* : * . : **:*:**:: :: . : .. : . ::: : *:* .: .:** *: * ** *.*.* ::* . * : ::* .: : . : : :. : :*: * ****:. . *:::*:: . ::::* *: *::*: :* . .:: : ****: . : *. *: .: : . *. * :*:.: .:*::: : : : . * :. .: . : *: :. : : . . : :. .: :::* : : .: *:: :* **::.:*:* ", "identical_positions": 149, "similar_positions": 486, "identity": "8.6%" }, { "cls_id": "homologset.agr.MGI:1289263", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3Z8K2-1", "uniprot_id": "CCD39_RAT", "id": "D3Z8K2-1", "name": "Coiled-coil domain-containing protein 39", "aln": "--------------MSSEFLSELHWEDGFAIPVANQENKILEDQLAKLHKEKSNLQDQLRDYEDRINSMSSHLKNVNQEFLFTQSLYKARECEIESEEHFKAIAERELGRVKDEIQQLEKEMAIILERKNDKENAIFKATQKLDGLKCQMNWDQQALEAWLEESAHKDSDSLTLQKYSQQDNNKIRALTLKLEKLTMECNEKRKLLDNELTETLSAQLELDKAAQDFRKIHVERQELIQQWENTIEQMQRRDQEIDNCALALARIKQEAREKEGVVREKIKFLENEVGNNVEYERRISIAERKVSKCRMEYQRQEANRNQLKDELDTLKTTLNRTSSDLEALRKNISKVKKDILDETGRLQKLKHHNEIVKHKLKMITEKTISIEEKATNMEDMLKEEEKNLKEVEVQLNIVKGVLFKKVQELQSAITKEKALGSEIEGTRSSLKHLNQRLHKLDFETLKQQEIMYSQDFYIQQVERRMSRLKGEIN-SEEKQALEVKIVELRKTMEERKSTLSLLEEQIKKLHNDLYFIKKSNGKNKDEKESLMNKIGELHLFVDRSEKELNKAKAVKEDLMIEDNLLKLQVKRARELLYSKAEEVLSLEKRKQQLCTAMEERVEEIKVHKAMLTSQIRYVDQQRQTVSSEFHERLSKIDKLKNRYEILTVVMLPPEGEEEKTQSYYVIKAAQEKEELQREGDSLDAKISKAEKEIYALQNTLQVLSSCNNNYKQSFKKVTPSS-DEYGIKIQLEEQKRS---ADEKYRCKQRQIRELQEDIQSMENTFEVIEHLANNAREKLSEKQTLSFQLRKETEEQKPKIQRVTKQCGRLRREIRILRQTNDETLE-EQDIQLREIIQFHKDIDQMLVNAMEN-AEIHVIFQTYFQQNGLELPTAK-GPSSRSSSQSS----LSSIR--------SLEDSIPISPPTAKVIELRFPGPP-ARSDSSRSSS-GSNSNIPKGKKLNK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D5Y1-1", "uniprot_id": "CCD39_MOUSE", "id": "Q9D5Y1-1", "name": "Coiled-coil domain-containing protein 39", "aln": "--------------MCSEFLSELHWEDGFAIPVANQENKILEDQLAKLREEKSNLQDQLHDYEERINSMTSHLKNVNQEFLFTQSLYKARESEIESEEHFKAIAERELGRVKNETQLLEKEMAIIRERKSQMENNIFKTTQKLDDLKCQMNWDQQALEAWLEESAHKDSDSLTLQKYSQQDDNKIRALTLQLEKLTMEYNEKRKLLDSELTETLSAQLELDKAAQDFRKIHLERQELIQQWENTIEQMQRRDQEIDNCALALSRIKQEAREKEGVVKEKIKFLENEVENNIEYERKISVAERKVSKCRMDYQRHEGNRSQLKDELDTLKTTLNRTSSDLQALRKNISKVKKDIFDETLRLQKLKHHNEVVKHKLKMITEKTLSIEEKATNMEDMLKEEEKGLKEVEVQLGIVKDVLFKKVQELQNEIAKEKALVSEIEGTRSSLKHLNKQLHKLDFETLKQQEIMYSQDFYIQQVERRMSRLKGEIN-SEEKQALEAKILELKKTMDEKKSTLSLLESQIKKLHNDLYFIKKSNGKNNDEKESLMNKISELNLFIDRSEKELSKAKAVKEDMMIEDNLLKLQVKRARELLYSKAEEVLSLEKRKQQLGKDMEERAEEIKVHKAMLTSQIRCVEQQRKTMSSEFHERLSKIDKLKNRYEILTVVMLPPEGEEEKTQSYYVIKAAQEKEELQREGDSLDAKINKAEKEIYALQNTLQVLNSCNSNYKQSFKKVTPSS-DEYALKIQLEEQKRT---ADERYRCKQRQIRELQEDIQSMENTFEVIGHLANNAKEKLTEKQTLAFQLRKETEEQKPKLQRITKQCGRLRREIRILKQTDNETLE-EQDIQLREIIQFHKDIDQMLVNAMEN-AEIHAIFKTYFEQNGLELPTAR-GPSSRSSSQSSS---LSSFR--------SLEDVTLQSPPTAKVIQLRFPEPPPATNDSSRSASSGSNSNIPKEKKLSK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UFE4-1", "uniprot_id": "CCD39_HUMAN", "id": "Q9UFE4-1", "name": "Coiled-coil domain-containing protein 39", "aln": "--------------MSSEFLAELHWEDGFAIPVANEENKLLEDQLSKLKDERASLQDELREYEERINSMTSHFKNVKQELSITQSLCKARERETESEEHFKAIAQRELGRVKDEIQRLENEMASILEKKSDKENGIFKATQKLDGLKCQMNWDQQALEAWLEESAHKDSDALTLQKYAQQDDNKIRALTLQLERLTLECNQKRKILDNELTETISAQLELDKAAQDFRKIHNERQELIKQWENTIEQMQKRDGDIDNCALELARIKQETREKENLVKEKIKFLESEIGNNTEFEKRISVADRKLLKCRTAYQDHETSRIQLKGELDSLKATVNRTSSDLEALRKNISKIKKDIHEETARLQKTKNHNEIIQTKLKEITEKTMSVEEKATNLEDMLKEEEKDVKEVDVQLNLIKGVLFKKAQELQTETMKEKAVLSEIEGTRSSLKHLNHQLQKLDFETLKQQEIMYSQDFHIQQVERRMSRLKGEIN-SEEKQALEAKIVELRKSLEEKKSTCGLLETQIKKLHNDLYFIKKAHSKNSDEKQSLMTKINELNLFIDRSEKELDKAKGFKQDLMIEDNLLKLEVKRTREMLHSKAEEVLSLEKRKQQLYTAMEERTEEIKVHKTMLASQIRYVDQERENISTEFRERLSKIEKLKNRYEILTVVMLPPEGEEEKTQAYYVIKAAQEKEELQREGDCLDAKINKAEKEIYALENTLQVLNSCNNNYKQSFKKVTPSS-DEYELKIQLEEQKRA---VDEKYRYKQRQIRELQEDIQSMENTLDVIEHLANNVKEKLSEKQAYSFQLSKETEEQKPKLERVTKQCAKLTKEIRLLKDTKDETME-EQDIKLREMKQFHKVIDEMLVDIIEENTEIRIILQTYFQQSGLELPTAS-TKGSRQSSRSPSHTSLSARS--------SRSTSTSTSQSSIKVLELKFPASSSLVGSPSRPSSASSSSSNVKSKKSSK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0CK98-1", "uniprot_id": "CCD39_DANRE", "id": "P0CK98-1", "name": "Coiled-coil domain-containing protein 39", "aln": "--------------MSSALLEEVGWDADFAIPVANAENKALEEQIRKKQKDILNLDNKLNKHKDVINALTEHLKNLKQEVSHNQALCKAKEKETESEVHLKALAERETGRLKQEITRLESQLTTLNEKKNAQENSIFKATQKIDELTSQLNWDQQTLEAFLQESAHKDEDTMAIIKYAKQDERKIKELTLNIEKLTLESNQKRKTLDNELTETVTSQIALDKTAESFRQAHTERQELISQWENTIEQMRKRDQDIQQCAMMLAELNQTIREKNDLIKERKDFLEREIENNKELERNIGTVERQAFRLRQQLQEEEKNQRRLQDEVEVLKGTVDRTATDVETSRSQLSSMKKDIQDKTTKVEEAQLHNAALEEKLRMVTEAVLNGEEQAAQMEQLLREQEQNIKEIDSQLLRQKELLFKKSQEVQALRDKEKNVTAEICATRTALSNLDSKLRKLDQNFLQQQMIISNQDFQIQMLERKTLHLQGKVN-TEEKKALEKKVADLAASLEEKKKTAANLNKQLKKLQDDIRCIKKDTEKIGAEKTNLSTKIQEVELFIETSEKERKKSRLKKQDSMVEKGLLKMEVQRLRNLLYDRADGVLTLEKRRLQLQTAMKEREEEIRVHREMLNKQVKLTEQERQGLSAAVNEAMSKIDKQRKRYEVLSVSLAPPEGEEDKSQAYFIIKAAQEKEELQRKGDELDAKIRKTEKEIHALENTLQVVNNCNSTHRKALTKVTESS-PAHQEKLKLEEQRRA---AEEKYKYKRRQTQELQEDIESMSNTLEGLLQEEKVLNEGIERTQAHVLSLNKDILSQEEKINRAVKQCAKYTKEIRSGKQSTEKTFE-ERDIELRELRDFNKSINKMLLDAMEGNPELSSILQIHFTQAGLSLPSPSSTPSSRLSSKPSSARSSASLHRSSNLSASSSPRSQSVSSPQMKTVDLGLGLSVTSPRG-SQPSSAGSSRSSSKCKSP--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VN57-1", "uniprot_id": "Q9VN57_DROME", "id": "Q9VN57-1", "name": "Coiled-coil domain-containing protein 39", "aln": "MNRTDDMKNASLNDYKLEAMASVGWAVDSDIPMASAENLAILKELTALRALKLELQQHMNSLDEREMAVERHTRNIEGTIQQNLTLYSSLKDDVIKEAHNVQLVILERNKIKEDLRKNNKELEEYTEYVKVTERKICQSKREIDELTSRIKSAKTTLVEWTEAMEDGNKGYQLIEKYYLDDQQKARELNIKRQLLQADIDKRRKQVVLLYDEQMTLEKNLERTACLYRSAHAERRQMVETWKSAVNQMTQREHDIQRSEIECAELAQKAQQTAQTYKEYDNQLTEVIENNRQVELAIESLNEESSDMKNQIQILIDATLLKEREIDGLRRELENLSNRVHLQRMDNRSQMKKRDEKAKELENFASVMEKVNARLKSVQNKALNAEQRLQILEEMMQAEETALRNLDKEQEKVNEMLYRTQRQVIELQDEEKVLKVQNDSLNSNLAAINRNQQQVNNELKRQTEIHYSLSFKCLEAERRLAEIKGLADDPEVEATNMARLNTLEQEYEKLQRLIATTEAQNKKLNYNMNNLVVQYNADEKELEMVRFKIKEAQVYCEGTVKRLRQIRYENSELIVDLNMVKMRCSDLEVGIGGCEQGTYDLEQHRLAFRRAIKDRTVELRSQEDVLLLKKKHLNEELSTLRADLGERKKQIEAMKARFELTAQLLGKNEDGSIMTSTQLKVVSAQERQMLADEGDALNKKVLKAEKEVVALENTLRQFDKSNDNYRKTFRSVDENSKDRERAELELKELEAAYCRELEKLKVLRCKAQHYQQKHAAQRAEEEDLISKIEKAKASRAEHSAVLEKIERELDDQRMKLDRANREIRTQLREIKARPFSEEYLAQFERDLSLQELEARNTKALNMITDLANSDESGTDIIGILLR-KGIKLPMHLKRTCSRVSWNSSSSGKSSQGQDTASYLNVKGKKFSCDGASARSSVSDMSSLKDDTSSTTSHSGLSIISLELPLPKKK--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .: * . **:*. ** : .:: : .*::.:.. .: :: * :*:: . . :* .: : : .* * :. * .::*:: :.:: * . *. * ::.:::* *..::: : :* : : . :.. : ** :*:.* : *.:: : * : :::** : * :: : *:::* :*. * **::::. *:.:::** :*: :*:.. : :.: * ::. :* . * : ** : * * :.: : * : *:: *: ::. :. :. * : . *. ::: .::: :: :*: : : .:. *:: :*:::: :* ::::: : : :*::. ::: :** : : . .: * :: . :::: : :* * . .* **: .::* : .* : : :: * :: : . : * ***: :: : * : ** * .:: : : *. : : :.: ::: .::*:. . . : . : . **::: : :::* *:: :. :* : : ::: . : : . * .:*: : *:*: : : *. . :.: : :***:: * :** *: *: *:***: **:***: ....*..::::: .* .* :::*:* . : *: : : : :. *:. : : : : . . .: .: :: .*. *::* :: :**: : : : *:*:.*:*: :. :*: : : . *: : *:.** ** * ... : . . . . :. *:.. . . *. ", "identical_positions": 131, "similar_positions": 359, "identity": "13.51%" }, { "cls_id": "homologset.agr.MGI:1289265", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R5A6-1", "uniprot_id": "TB22A_MOUSE", "id": "Q8R5A6-1", "name": "TBC1 domain family member 22A", "aln": "MASDGARKQFWKRSN------------------SKVPGSIQHVYGAQHPPFDPLLHGTLLKSTPKVPTTPVKAKRVSTFQEFESNTSDAWDAGEDDDELLAMAT-ESLNSEVVMETAHRVLRNHSQRQSQPSQKT-TEPEPEPQPIAE--------------------------------PPVPPSGDLRLVKSVSESHTPCPSESTGDTVPLQRSQSLPHSATVTLSGTSDPHALADSALSKRETSRLDKFKQLLAGPN--------TDLEELRKLSWSGIPKPVRPMTWKLLSGYLPANVDRRPATLQRKQKEYFAFIEHYYSSRNDEVHQDTYRQIHIDIPRMSPEALILQPK-VTEIFERILFIWAIRHPASGYVQGINDLVTPFFVVFICEYTDREDVDKVDVSS----VPAEVLRNIEADTYWCMSKLLDGIQDNYTFAQPGIQMKVKMLEELVSRIDERVHRHLDGHEVRYLQFAFRWMNNLLMRELPLRCTIRLWDTYQSEP------------------------------------------------------------EGFSHFHLYVCAAFLVRWRREILEERDFQELLLFLQNLPTARWDDQDVSLLLAEAYRLKFAFADAPNHYKK--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZPV1-1", "uniprot_id": "A0A8I5ZPV1_RAT", "id": "A0A8I5ZPV1-1", "name": "", "aln": "MASDGARKQFWKRSN------------------SKVPGSIQHVYGAQHPPFDPLLHGTLLKSTPKVPTTPVKAKRVSTFQEFESNTSDAWDAGEDDDELLAMAT-ESLNSEVVMETAHRVLRNHSQRQNQPSQK---KPEPEPQPIAE--------------------------------PPVAPSGDLRLVKSVSESHTPCPSESTSDTVPLQRSQSLPHSATVTLSGTSDTHALGGSALSKRETSRLDKFKQLLAGPN--------TDLEELRKLSWSGIPKPVRPMTWKLLSGYLPANVDRRPATLQRKQKEYFAFIEHYYNSRNDEVHQDTYRQIHIDIPRMSPEALILQPK-VTEIFERILFIWAIRHPASGYVQGINDLVTPFFVVFICEYTDQEDVDKVDVSS----VPAEVLRNIEADTYWCMSKLLDGIQDNYTFAQPGIQMKVKMLEELVSRIDERVHRHLDGHEVRYLQFAFRWMNNLLMRELPLRCTIRLWDTYQSEP------------------------------------------------------------EGFSHFHLYVCAAFLVRWRREILEERDFQELLLFLQNLPTARWDDQDVSLLLAEAYRLKFAFADAPNHYKKSSTPLPRH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8WUA7-1", "uniprot_id": "TB22A_HUMAN", "id": "Q8WUA7-1", "name": "TBC1 domain family member 22A", "aln": "MASDGARKQFWKRSN------------------SKLPGSIQHVYGAQHPPFDPLLHGTLLRSTAKMPTTPVKAKRVSTFQEFESNTSDAWDAGEDDDELLAMAA-ESLNSEVVMETANRVLRNHSQRQGRPTLQEGPGLQQKPRPEAE--------------------------------PPSPPSGDLRLVKSVSESHTSCPAESASDAAPLQRSQSLPHSATVTLGGTSDPSTLSSSALSEREASRLDKFKQLLAGPN--------TDLEELRRLSWSGIPKPVRPMTWKLLSGYLPANVDRRPATLQRKQKEYFAFIEHYYDSRNDEVHQDTYRQIHIDIPRMSPEALILQPK-VTEIFERILFIWAIRHPASGYVQGINDLVTPFFVVFICEYIEAEEVDTVDVSG----VPAEVLCNIEADTYWCMSKLLDGIQDNYTFAQPGIQMKVKMLEELVSRIDEQVHRHLDQHEVRYLQFAFRWMNNLLMREVPLRCTIRLWDTYQSEP------------------------------------------------------------DGFSHFHLYVCAAFLVRWRKEILEEKDFQELLLFLQNLPTAHWDDEDISLLLAEAYRLKFAFADAPNHYKK--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q08484-1", "uniprot_id": "GYP1_YEAST", "id": "Q08484-1", "name": "GTPase-activating protein GYP1", "aln": "MGVRSAAKEMHERDHNSDSSSLVTSLMKSWRISSASSSKKPSLYKMNTTESTSLPSGYASSADRDRRTSDGNFEAMAKQQASTRRTSNSYSPLRYVNPTLSTASNESPRPALLLRQHHQRHHHHQQPRHSSSGSVGNNCSNSTEPNKKGDRYFKDLDEDWSAVIDDYNMPIPILTNGGFGTPVAPTRTLS-RKSTSSSINSISNMGTSAVRNSSSSFTYPQLPQLQKEKTNDSKKTQLEIENERDVQELNSIIQRISKFDNILKDKTIINQQDLRQISWNGIPKIHRPVVWKLLIGYLPVNTKRQEGFLQRKRKEYRDSLKHTFSDQHS-RDIPTWHQIEIDIPRTNPHIPLYQFKSVQNSLQRILYLWAIRHPASGYVQGINDLVTPFFETFLTEYLPPSQIDDVEIKDPSTYMVDEQITDLEADTFWCLTKLLEQITDNYIHGQPGILRQVKNLSQLVKRIDADLYNHFQNEHVEFIQFAFRWMNCLLMREFQMGTVIRMWDTYLSETSQEVTSSYSMSSNDIKPPVTPTEPRVASFVTPTKDFQSPTTALSNMTPNNAVEDSGKMRQSSLNEFHVFVCAAFLIKWS-DQLMEMDFQETITFLQNPPTKDWTETDIEMLLSEAFIWQSLYKDATSHWL---------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. .* *:: :*.: * ... :* : . .* * : . *: : : ::. * .**:::.. . : *: *: ** .. :::. :: ::*.* : .: . . ...* : .* .*: * **.*.* .. . .:. . . * : *: . : *.*. . .:*:...*:.: * :: : : ::**::**.**** **:.**** ****.*..*: . ****:*** ::* :..::. . *::**.***** .*. : * * * : ::***::********************** .*: ** .::* *::.. : * : ::****:**::***: * *** ..**** :** *.:**.*** ::.*:: ..*.::******** *****. : .**:**** **. ..:..**::******::* : * * **** : **** ** * : *:.:**:**: : : **..*: ", "identical_positions": 182, "similar_positions": 178, "identity": "28.04%" }, { "cls_id": "homologset.agr.MGI:1289273", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O55000-1", "uniprot_id": "PP1RA_RAT", "id": "O55000-1", "name": "Serine/threonine-protein phosphatase 1 regulatory subunit 10", "aln": "MGSGPIDPKELLKGLDSFLTRDGEVKSVDGIAKIFSLMKEA-RKMVSRCTYLNIILQTRAPEVLVKFIDVGGYKLLNSWLTYSKTTNNIPLLQQILLTLQHLPLTVDHLKQNNTAKLVKQLSKSSEDEELRKLASVLVSDWMAVIRS---------------------QSSTQPAEKDKKKRKEEGKSRTTLPERPLTEVKAETRAEEAPEKKKEKPKSLRTTAPSHAKFRSTGLELDTPSLVPVKKNSSTVVVSDKYNLKPIPLKRQSATAAPGDAAPPAEKKYKPLNTTPN----TTKEIKVKIIPPQPMEGLGFLDALNSAPVPGIKIKKKKKVLSPTAAKPSP---FEGKTSTEPSTAKPSSPEPAAPAEPMDTDRPGTPVPAVEVPELMDAASSEPGALDAKPVESPGDPNQLTRKGRKRK----------TVTWPEEGKLREYFYFELDETERVNVNKIKDFGEAAKREILSDRHAFETARRLSHDNMEEKVPWVCPRP--------------LVLPSPLVIPGSNSQERYIQAEREKGILQELFLNKESPHEPDPEPYEPIPPKLIPLDEECAMDETPYVETLEP-----GGSGGSPDGAGGSKLPPVLANLMGSMGAGKSPQGPGGGGINVQEILTSIMGSPNNHPSEELLKQ---PDYSDKLKQMLVPHGLLG-------------PGPVANGFPPGGPGGPKGMQHFPPGPG------------------------------------------------------------------GPMPGPHGGPGGPVG-----------------------PRLLGPPPPSRGGDPFWDGPGDPMRGGPMRGGPGPG--------PGPYHRGRGGRGGNEPPPPPP-FRGARGGRSGGGP--------PNGRGGPGGGGMVGGGGHRPHEGP--------------GGSMG--SGHRSHEGPGGSMGS----------------------------------------------------------------GHRSHEGPGHGG-PHGHRPHDVPSHRGHDHRGPPPHEHRGHDG--HGGGGHRGHDGG----------HSHGGDMSNRPVCRHFMMKGNCRYENNCAFYHPGVNGPPLP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80W00-1", "uniprot_id": "PP1RA_MOUSE", "id": "Q80W00-1", "name": "Serine/threonine-protein phosphatase 1 regulatory subunit 10", "aln": "MGSGPIDPKELLKGLDSFLTRDGEVKSVDGISKIFSLMKEA-RKMVSRCTYLNIILQTRAPEVLVKFIDVGGYKLLNNWLTYSKTTNNIPLLQQILLTLQHLPLTVDHLKQNNTAKLVKQLSKSSEDEELRKLASVLVSDWMAVIRS---------------------QSSTQPAEKDKKKRKEEGKSRTTLPERPLTEVKAETRAEEAPEKKKEKPKSLRTTAPSHAKFRSTGLELDTPSLVPVKKNSSTVVVSDKYNLKPIPLKRQSATAAPGDAAPPAEKKYKPLNTAPN----TTKEIKVKIIPPQPMEGLGFLDALNSAPVPGIKIKKKKKVLSPTAAKPSP---FEGKTSTEQSTAKPSSPEPAPPAEPMDTDRPGTPVPPVEVPELMDAASSEPGALDAKPVDSPGDPNQLTRKGRKRK----------TVTWPEEGKLREYFYFELDETERVNVNKIKDFGEAAKREILSDRHAFETARRLSHDNMEEKVPWVCPRP--------------LVLPSPLVIPGSNSQERYIQAEREKGILQELFLNKESPHEPDPEPYEPIPPKLIPLDEECAMDETPYVETLEP-----GGSGGSPDGAGGSKLPPVLANLMGSMGAGKSPQGPGGGGINVQEILTSIMGSPNSHPSEELLKQ---PDYSDKLKQMLVPHGLLG-------------PGPVANGFPPGGPGGPKGMQHFPPGPG------------------------------------------------------------------GPMPGPHGGPGGPVG-----------------------PRLLGPPPPSRGGDPFWDGPGDPMRGGPMRGGPGPA--------PGPYHRGRGGRGGNEPPPPPP-FRGARGGRSGGGP--------PNGRGGPGGGGMVGGGGHRPHEGP--------------GGSMG--SGHRSHDGPGGNMGSGHRSHDGPGGNMGG------------------------------------------------SGGHRSHEGPGHGG-PHGHRPHDVPSHRGHDHRGPPPHEHRGHDG--HGGGGHRGHDGG----------HSHGGDMSNRPVCRHFMMKGNCRYENNCAFYHPGVNGPPLP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96QC0-1", "uniprot_id": "PP1RA_HUMAN", "id": "Q96QC0-1", "name": "Serine/threonine-protein phosphatase 1 regulatory subunit 10", "aln": "MGSGPIDPKELLKGLDSFLNRDGEVKSVDGISKIFSLMKEA-RKMVSRCTYLNILLQTRSPEILVKFIDVGGYKLLNNWLTYSKTTNNIPLLQQILLTLQHLPLTVDHLKQNNTAKLVKQLSKSSEDEELRKLASVLVSDWMAVIRS---------------------QSSTQPAEKDKKKRKDEGKSRTTLPERPLTEVKAETRAEEAPEKKREKPKSLRTTAPSHAKFRSTGLELETPSLVPVKKNASTVVVSDKYNLKPIPLKRQSNVAAPGDATPPAEKKYKPLNTTPN----ATKEIKVKIIPPQPMEGLGFLDALNSAPVPGIKIKKKKKVLSPTAAKPSP---FEGKTSTEPSTAKPSSPEPAPPSEAMDADRPGTPVPPVEVPELMDTASLEPGALDAKPVESPGDPNQLTRKGRKRK----------SVTWPEEGKLREYFYFELDETERVNVNKIKDFGEAAKREILSDRHAFETARRLSHDNMEEKVPWVCPRP--------------LVLPSPLVTPGSNSQERYIQAEREKGILQELFLNKESPHEPDPEPYEPIPPKLIPLDEECSMDETPYVETLEP-----GGSGGSPDGAGGSKLPPVLANLMGSMGAGKGPQGPGGGGINVQEILTSIMGSPNSHPSEELLKQ---PDYSDKIKQMLVPHGLLG-------------PGPIANGFPPGGPGGPKGMQHFPPGPG------------------------------------------------------------------GPMPGPHGGPGGPVG-----------------------PRLLGPPPPPRGGDPFWDGPGDPMRGGPMRGGPGPG--------PGPYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGP--------PNGRGGPGGG-MVGGGGHRPHEGP--------------GGGMGNSSGHRPHEGPGGGMGSGHRPHEGPGGSMGGGGGHRPHEGPGGGISGGSGHRPHEGPGGGMGAGGGHRPHEGPGGSMGGSGGHRPHEGPGHGG-PHGHRPHDVPGHRGHDHRGPPPHEHRGHDGPGHGGGGHRGHDGG----------HSHGGDMSNRPVCRHFMMKGNCRYENNCAFYHPGVNGPPLP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7KU01-1", "uniprot_id": "Q7KU01_DROME", "id": "Q7KU01-1", "name": "", "aln": "--MPRIVPLQLLRCLRVLLDNNGGILSAVEVKRISGLMAKYSKKLVSKCVYVQILKSTKT-ELLGDFMAVGGWSLVYTWLNDAIRAMNWPLVQEILELLLLSPVDVNRLKINSAPILVKGLCKDGGNEGVRILAKRLVEQWLKIVTENTSMTIQGAAPHIAATTASQVPASVSGAGSASVPDSASSSDSTDSAGAPVTYTITSAANSSNSNSITIKWKPLLDNPDGGDETDSGTQSKDNEVEHLEKGSSATHLLADASLGKKSGLDDSSSAAEVKSGEDVDNKKHKSSKSDKSKRSEKEREKDRKKESSSHRSSSSSHKSSSSSSSSSSKSSSSKSSSSSSSSHRSSSDKYRDKDKARSSSGSSSSSKDRERSSGSSSSSSNKHKSSKSSSSSSSSSSSSSGSSSSKDRKSSSSTSSSSSSSRQDKDKDNKLMPPPAVAASNAAGTSPTASAKESDAQKPRSIPIMSRKASISIEIRRDTEKTATVKTYQSKFRSHGLTEEAPPPPSRKGLKKPTSSAVAASPALMAVPSSLKRPSPPPRDLSTDKKAKIDINNVAGHVERPGAAKLIAPKKIQTLVETNLFSDALAASIEPKKVVKRKRTSATSPTDKDAPLAPLKFYQDTLDESKSEEKSDDSSKENDDARSSSPGKDTDADDDDIPLKRVKEDIEQKVQKAKAAAGGEGGEAGNTSDNAEDLPEEPKKPGPGCGPDGPPGVLTLHRRKGPKKKLTWQSEEKLTQIRYFEVDRSERVNVMKQTFLEMKNMERFSERDALTIARRGFDDTMEPQMEWRPLLEVDNVPDHPNGNLSKQRQVQMDREATTLRALYFSPDMIPDSPAEAELEPHFAHDIPVIPMDDLTGNPDAVNDYSALAWPEPKKYAPSSGVGANISGSDMGFNDNMLTGLGAGPNLMQNPFDPFMGGMPAPTGMPPGPNMMPNQVPNGTPQIWQNQMGPVGGPPGVPPMMNGPGGPGMDMSNMNMNNMPPQNFMGNQFGSPVSPFGSGPPPGFNQYPPMMMNGPGPGPVMGP---NGPVMGPNGPMMNGPPNGPMMNGPPNGMGPGLMMGGPRNNNNNNNRNKNNGGGIWRSGGNNFQENSGGNWRSAGSGPNRGGGGGNGNTGVCKQFMR-GHCNMGKNCKYVHPQKKRL---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * :**: * :* .:* : *. : :* .** : :*:**:*.*::*: .*:: *:* .*: ***:.*: .**. : : * **:*:** * *: *::** *.:. *** *.*.. :* :* **. **.:*: :: . :*.. * . . . .... * . *:* . :.: .. .:. * *.* .. . : * . :. * .::* :::* * *. .* .* .. :**:*. :: . :* . * ... .. . .: .*:. .. * ...*. *.:::: *. :..* .:. *:...**.: :. .:. ... .. . .. .::* ..*: .:* .*...... : ..*: * :*: .: . : .:::: . * . : . ** * . *.: . . .. :. .* * . *: :. *.* .: : ... :: :*: : * * . : *.** * * : . . . ::** .:.. :. . . * .::. .*. : ..... : :: :* *. .. .::: : * .:*::: .. * * * : * **.** *: : * *: .. *. * * * :: .*. :*.: : . : *.*.. * * : . .. * : . . *.. *.** * * *. * * . *:: * ** * . . *** .*.. : . :** .* *:* * : . :::.. :::.* . **...: :.** :. **. .* **::** *:*. :** : ** : ", "identical_positions": 178, "similar_positions": 329, "identity": "15.55%" }, { "cls_id": "homologset.agr.MGI:1289274", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BGA5-1", "uniprot_id": "KRR1_MOUSE", "id": "Q8BGA5-1", "name": "KRR1 small subunit processome component homolog", "aln": "MAT-SAEAPAKEAQKRDSQPQKQKRETQDEAELLTVPDGWKEPAFSKEDNPRG--LLEESSFATLFPKYREAYLKECWPLVQKALNEHHVKATLDLIEGSMTVCTTKKTFDPYIIIRARDLIKLLARSVSFEQAVRILQDDVACDIIKIGSLVRNKERFVKRRQRLIGPKGSTLKALELLTNCYVMVQGNTVSAIGPFSGLKEVRKVVLDTMKNIHPIYNIKTLMIKRELAKDSELRSQSWERFLPQFKHKNVNKRKEPKKK-SVKKEYTPFPPPQPESQIDKELASGEYFLKASQKKRQKMEAIKAKQAEALTKRQEERNKAFIPPKEKPAVK---PKEASTETKIDVAAIKEKVKKAKTKKLGALTAEEVKLKMEADEKKQKRKK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13601-1", "uniprot_id": "KRR1_HUMAN", "id": "Q13601-1", "name": "KRR1 small subunit processome component homolog", "aln": "MASPSLERPEKGAGKSEFRNQKPKPENQDESELLTVPDGWKEPAFSKEDNPRG--LLEESSFATLFPKYREAYLKECWPLVQKALNEHHVNATLDLIEGSMTVCTTKKTFDPYIIIRARDLIKLLARSVSFEQAVRILQDDVACDIIKIGSLVRNKERFVKRRQRLIGPKGSTLKALELLTNCYIMVQGNTVSAIGPFSGLKEVRKVVLDTMKNIHPIYNIKSLMIKRELAKDSELRSQSWERFLPQFKHKNVNKRKEPKKK-TVKKEYTPFPPPQPESQIDKELASGEYFLKANQKKRQKMEAIKAKQAEAISKRQEERNKAFIPPKEKPIVK---PKEASTETKIDVASIKEKVKKAKNKKLGALTAEEIALKMEADEKKKKKKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NAE1-1", "uniprot_id": "A0A8M1NAE1_DANRE", "id": "A0A8M1NAE1-1", "name": "KRR1 small subunit processome component", "aln": "-----MAAPTESTSETTTDKKQKKSKNTDDADLLTVPDDWKEPKFTKADNPKG--LLEESSFATLFPKYREAYLKECWPLVQKALAELFINATLDLIEGSMTVNTTKKTFDPYSIIRARDLIKLLARSVPFEQAVRILDDDMACDIIKIGTLVRNRERFVKRRQRLIGPKGSTLKALELLTNCYVMVQGNTVSALGPFNGLKEVRKVVLDTMKNIHPIYNIKTLMIKRELANDPELRTQSWGRFLPNFRHKSLSKRKQPKKK-RVKKEYTPFPPPQPESKIDKELATGEFFLRESEKRRKKMSEIKVKQAEALSKRQEERKKAFVPPKEKTAVKK--SKPATSENKIDVQAIKEKVKKAKNKKLGAPPVNPDMSSAKVGKQKKNKS-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VPU8-1", "uniprot_id": "KRR1_DROME", "id": "Q9VPU8-1", "name": "KRR1 small subunit processome component homolog", "aln": "------------MSESEAEETKISTEPVDNAWSMKIP------AFRQEDNPHG--MVEESSFATLFPKYRERYLKEVWPLVEQCLAEHHLKAELDLMEGSMVVKTSRKTWDPYIIIKARDMIKLMARSVPFEQAKRVLQDDIGCDIIKIGNLVHKKEKFVKRRQRLIGPNGATLKSIELLTDCYVLVQGNTVSALGPYKGLQQVRDIVLETMNNVHPIYNIKALMIKRELMKDPRLANEDWSRFLPKFKNKNISKRKQPKVK-KQKKEYTPFPPSQPESKVDKQLASGEYFLNQEQKQAKRNQERTEKQKEAAKRQDERRNKDFVPPTEESAASSRKKEDGSSSSKVDVKALKAKLIKANKKARSS---------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P25586-1", "uniprot_id": "KRR1_YEAST", "id": "P25586-1", "name": "KRR1 small subunit processome component", "aln": "---------------MVSTHNRDKPWDTDDIDKWKIE------EFKEEDNASGQPFAEESSFMTLFPKYRESYLKTIWNDVTRALDKHNIACVLDLVEGSMTVKTTRKTYDPAIILKARDLIKLLARSVPFPQAVKILQDDMACDVIKIGNFVTNKERFVKRRQRLVGPNGNTLKALELLTKCYILVQGNTVSAMGPFKGLKEVRRVVEDCMKNIHPIYHIKELMIKRELAKRPELANEDWSRFLPMFKKRNVARKKPKKIRNVEKKVYTPFPPAQLPRKVDLEIESGEYFLSKREKQMKKLNEQKEKQMEREIERQEERAKDFIAPEEE-------------------------AYKPNQN-------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . *: .: * : **. * : ***** ******** *** * * :.* : : . ***:****.* *::**:** *::***:***:****.* ** ::*:**:.**:****.:* ::*:********:**:* ***::****.**::********:**:.**::** :* : *:*:****:** ******* : ..* .:.* **** *:::.: ::* * : ** ******.* ::* :: :**:** :*: :: . . ** * .::*.* * *:.* *: *.: : ", "identical_positions": 146, "similar_positions": 88, "identity": "37.73%" }, { "cls_id": "homologset.agr.MGI:1289279", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A869-1", "uniprot_id": "A0A8I6A869_RAT", "id": "A0A8I6A869-1", "name": "", "aln": "MPGAEEQAVLAES-GDEEPG--------------DPRLRLLGTFVARSLRPAAGTWERCAGTAEAGRLLQAFLDHN-------------------------------------------------AAAGPCPLLVVQSGPGGLVVRP--GLDAGPEPNQARAKGLFFLRTRS--EPPGNHSLRGTVLCGDLPAVP-LEHLAPLLSEVIIPVLDNEKNHLDWPHMVCQDIRHHAHSLQSDLLVILEHMKGRTLLPLPVGSEKVEFVD-GQSEPVLD-SIDKSTVYAMESAVIKWSHQVQVVLKRES------SQPLIQGEKP-------TPKVELEFWKSRCEDLEHIYNQLMTIKVRGMAGLLDKLQSSYLPAFKAMFQDVEAALTEAQDIRVHLLPLQQHLDILENMEFPEVKGRLRPLLHVVCLIWANCKWYRSPGRLTVLLQEICNLLIQQASNYLSPEDLLRSEVEESQRKLQIVSDTLSFFKQAFQDRREHLHTYFKE-----------------DSEVRAWDFQASLVFVR-LDGFLGRLRMVEDLLKTALDFNKLEKLEFSGLRGNSLSQKVQQMHEEFEEMYKVFLDCSYDCLNPES---MEFENDVCGFNKRVEDLDRRLGTILIQAFDDVPEVEHAFKLLDITGTLVERPLVAQDVSHKYLALIRMFNTELDAVRIIYSQHIREEVEHGFS--PVHKNMPTMAGGIRWAQELRQRIKGP-FSNFKNIPHWCLQSA--------EGKRMIQKYEDLLTLLEEYERRLYEDWCQTVSEKSQRNLSLPLLHRDPITKQLSVNFNSQLISVLKEMNYLQPTEVKP--------IPETAAAMFSSREFYRQLVANLELMANWYNKVITT-LLEVEFPLVEEELQNIDLRLRAAEETLSWKTEGIWDYAMQITNSIHDLERRIQKTKDNVEEIQTIMKTWVS-PIFKRKDGKKECPLSLDDQQDLLEKYYSLIRESGLKIHALVQENLVLFAADPA-----------------------SSTWKSYVGHIDSMLLDGFFLAIECSLKYLLENTECKP-----------------------------------------------GLTPIFEAQLNLVTPELVFYPSLDSGVKGGLYDIVQSLVTSIFAVPSLVPRLSPHSGSPHYQGDLEEM-----------------ADLASLRSLLLERVQT------------MMTLCCSYRNTLSQYSY--------------LYVEDRKEALGQFLLYGHVLTPE--EIEAHVEDGIPESPP--------LLHHFKDQIDSYEKLYEDVVSLEPSKVFDGWMRVDVRPFKASLLNTIKKWSLMFKQHLVDFVTNSLADLDSFIKSTECGLLKRVEKGDFQGLVEIMGHLVTLKERQSSTDDMFEPLKQTIELLKSYEQELPETVFKQLEELPEKWKNVKKMAITVRQQVAPLQANEVALLRQRCSAFDDEQQQFQERFHKEAPFRFDSINPHQMLDVWHMEIQHMESTMATISKSADLFEVNVPDYKQLRQCRKEACQLKELWDTIGMVTSSIQAWEATSWRNISVEAMDSECKQFARQIRNLDKEFRTWDAFTGLESTVLNTLTSLRAVAELQNPAIRERHWRQLMQATG----------VNFTMDRDTTLAHLLQLQLHHFEDEVRDIVDRAVKEMSMEKTLKELQTTWASMEFQYETHA-RTHIPLLQSDEDLIEVLEDNQVQLQNLMMSKYVAFFLEEVSSWQKKLSTADSVISIWFEVQRTWSHLESIFIGSEDIRAQLPQDAKRFESIDSDFRELVYDAQKTPNVVEATN-KSGLYEKLEDIQSRLCLCEKALAEYLDTKRLAFPRFYFLSSSDLLDILSNGTAPQQVQRHLSKLFDNMAKMQFQLDASQNPTKTSLGMYSKE-EEYVAFS-------EPCDCSGQVEIWLNRVLRHMKATVRHEMTEAVTAYEEKPRDQWLFDYPAQVALTCTQIWWTTEVGIAFARLEEGYENAMKDYYKKQVAQLKTLITMLIGQLSKGDRQKIMTICTIDVHARDVVAKMIAQKVDNAQAFLWLSQLRHRWDDE------------------AKHCFANICDAQFLYSYEYLGNTPRLVITPLTDRCYITLTQSLHLTMSGAPAGPAGTGKTETTKDLGRALGIMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVVAVQVKSIQDAIRDKKQRFSFLGEEISLDPSVGIFITMNPGYAGRTELPENLKALFRPCAMVVPDFELICEIMLVAEGFIEARLLARKFITLYRLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDPDRPEDQVLMRSLRDFNIPKIVTDDMPVFMGLISDLFPALDVPRKRDLDFEAVVRKAIVDLKLQAEDNFVLKVVQLEELLAVRHSVFIVGGAGTGKSQVLKSLHKTYQIMRCRPVWTDLNPKAVTNDELFGIINPATREWKDGLFSSIMRELANISHDGPKWILLDGDIDPMWIESLNTVMDDNKVLTLASNERIPLNPTMRLLFEISHLRTATPATVSRAGILYINPADLGWNPPVNSWIDQREVQTERANLTILFDKYLPTCLDTLRTRFKKIIPVPEQSMIQMLCYLLECLLTKEAVPAD-------------------------CPKEIYELYFVFAAIWAFGSSMVQDQLVDYRAEFSKWWLTEFKTVKFPSQGTVFDYYIDQETKKFEPWGKLIP----QFEFDPEMPLQACLVHTSETIRVCYFMERLMERRRPVMLVGSAGSGK------------------------------------------SVLVGAKLSSLNPEEYMVKNVPFNYYTTSAMLQAVLEKPLEKKAGRNYGPPG-NRKLIYFIDDMNMPEVDAYGTVQPHTVIRQHLDYGHWYDRNKLSLKEIMNVQYISCMNPTAGSFTINPRLQRHFSVFALCFPGADALSSIYSTILTHHLK--LGNFPTTLQKSIPSLINLAVTFHQKIATTFLPTAIKFHYIFNLRDFANIFQGILFSS---------------TECVKSTQDLVKLYLHESDRVYRDKMVEEKDFNLFDKLQTEFLKKNFDDSKGMLEQTQNLNMYCHFANGIGEPKYMPVQSWDLLSQTLVEALESHNEVNAVMDLVLFEDAIHHICHINRILESPRGNALLVGVGGSGKQSLTRLAAFISSMDVFQITLRKGYQIPDFKVDLASLCLKAGVKNLSTVFLMTDAHVADERFLVLINDLLASGEIPDLYSEEEEENIINNVRNEVKSQGLIDSRENCWKFFIERVRRQLKVTLCFSPVGNKLRIRSRKFPAIVNCTAINWFHEWPQEALESVSLRFLQNT-KNIEPAVKQSISKFMAFVHISVNKISQSYLINEQRYNYTTPKSFLEFIRLYQSLLERNGKELQSKVERLENGLLKLHSTSAQVDDLKAKLATQEVELRQKNEDTDKLIQVVGVETSKVSREKAIADEEEQKVALIMLEVQQKQKDCEEDLAKAEPALTAAQAALNTLNKTNLTELKSFGSPPLAVSNVSAAVMVLMAPGGKVPKDRSWKAAKITMTKVDSFLDSLIHFDKENIHENCLKAIRPYLQDPAFNPEFVATKSYAAAGLCSWVINIVRFYEVFCDVEPKRQALNKATSDLTAAQEKLAAIKAKITHLNENLAKLTTKFEKATAEKLKCQQEAEVTAGTISLANRLVGGLASENVRWAEAVQNFRQQERTLCGDILLTTAFISYLGFFTKKYRKSLMDGTWKPYLSQLKVPIPTTPTLDPLKMLTDDADVATWQNEGLPADRMSMENATILINCERWPLMVDPQLQGIKWIKNKYGEELRVTQIGQKGCLQTIERALEAGDVVLIENLEESIDPVLGPLLGREVIKKGRFIKIGDKECEFNPKFRLILHTKLANPHYQPELQAQATLINFTVTRDGLEDQLLAAVVSMEIPDLEHLKSDLTKQQNGFKITLKTLEDNLLSRLSSASGNFLGETALVENLEVTKQTAAEVQEKVQEAKLTEVKINEAREHYRPAAARASLLYFIMNDLSKIHPMYQFSLKAFSIVFQKAVEKAAPSEDVKERVTNLIDSITFSVYQYTTRGLFECDKLTYLAQLTFQILLVNQEVNAAELDFLLRAPVQAGTPSPMEFLSHQAWGSIKALSSMEEFCNLDRDIEGSAKSWKKFVESECPEKEKFPQDWKNKTGLQRLCMMRAMRPDRMTYAMRDFVEEKLGSKYVMGRPLDFVSSFEESGPATPMFFILSPGVDPLKDVENQGKKLGYTFNNRNFHNVSLGQGQEVVAEAALDLAAKKG-HWVILQNIHLVAKWLSTLEKKLEELSEES----HPDFRVFISAEPAPSPEGHIIPQGILENSIKITNEPPTGMHANLHKALDNFTQDTLEMCSRETEFKTILFALCYFHAVVAERRKFGPQGWNRSYPFNTGDLTISVNVLYNFLEANTKVPYDDLRYLFGEIMYGGHITDDWDRRLCRTYLEEFIRPEMLEGELSLAPGFPLPGNMDYSGYHQYIDAELPPESPYLYGLHPNAEIGFLTQTSEKLFRTVLEMQPRDSQAGDGAGSTREEKVKAFLEEILDRVTDEFNIPELMAKVEERTPYIVVALQECERMNILTREIQRSLRELHLGLQGELTMTSEMENLQNALYLDVVPEPWARRAYPSTAGLAAWFLDLLNRIKELETWTGDFVMPSTVWLTGFFNPQSFLTAIMQSMARKNEWPLDQMALQCDVTKKNREEFRSPPREGAYIYGLFMEGACWDTQGRSEAHGKGISRPKRSKGRFMKHSAPPVAGIIAEAKLKDLTPPMPVMFLKAIPAEKQDCRSIYACPVYKTCQRGP-TYVWTFNLKTKENPSKWVLAGVALLLQI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B1AR51-1", "uniprot_id": "B1AR51_MOUSE", "id": "B1AR51-1", "name": "", "aln": "MPGAKEQAALAES-GDEEPG--------------DPRLRLLGTFVARSLRPAAGTWERCAGTAEAGRLLQAFLDHN-------------------------------------------------AASDPRPLLVVQSGPGGLVVTP--GLDAGPEPSRARAKGLFFLRTKS--EPPGNHSLRGTVLCGDLPAVP-LEHLAPLLSEVIIPVLANEKNHLEWPHMVCQDIRHHAHTLKSDLLVIFEHMKGRTLLPLPVGSEKLEFVD-GHSEPVSD-AIDKSTLYAVESAVIKWSHQVQVVLKRES------SQALIQGQNP-------TPKVELEFWKSRCEDLEHIYNQLMTIKVKGMAELLDKLQSSYLPAFKAMFRDVEAALTEAQDIHVHLLPLQQHLDILENVEFPKVKGRLRPLLHVVCLIWATCKWYRSPGRLTVLLQEICNLLIQQASNYLSPEDLLRSEVEESQKKLQVVSDTLSFFKQAFQDRREHLHTYFKE-----------------DSEVRVWDFQASLVFVR-LDGFLGRVHMVEDLLKTALDLNNLEKLEFSGLRGNSLSQKVQRMHEEFEEMYKVFLDCSYDCLDPKG---TEFENDVCEFNKRVEDLDRRLGTILIQAFDDAPDVEHAFKLLDITGTLIKRPLVAQDVSQKYLALIRMFSTELDAVRVIYSQHIQKEAEHGFS--PVHKNMPTMAGGICWAQELRQRVKGP-FGNFKNIPHLYLQSA--------EGKRMIQKYEDLLSLLEEYERRLYEDWCQTVSEKSQYNLSLPLLHRDPNTKQLSVNFNPQLISVLKEMNYLQPSEVKT--------IPETAAAMFSSREFYRQLVANLELMANWYNKVIKI-LLEVEFPLVEEELQNIDLRLRAAEETLSWKTEGIWDYAMQITNSIHDLEQRIQKTKDNVEEIQNIMKTWVS-PIFKRKDGKKEWPLSLDDQQDHMEKYYSLIQESGLKIHALVQENLVLFAADPA-----------------------SSIWKSYVNYIDSMLLDGFFLAIECSLKYLLENTECKP-----------------------------------------------GLTPVFEAQLNLVTPELVFHPSLDSGVKGGLYDIVQSLVTRIFAMPSLVPRLSPHSGSPHYQGDLEDM-----------------ADLAGLRSVLMERVQN------------MMTLCCGYRNTLSQYSY--------------LYVEDRKEILGQFLLYGHVLTPE--EIEAHAEDGIPENPP--------LLHHFKDQIDSYEKLYEEVVSLEPTKVFDGWMRVDVRPFKASLLNTIKKWSLMFKQHLVDFVTNSLSDLDSFIRSTESGLLKRVEKGDFQGLVEIMGHLVTLKERQSSTDDMFEPLKQTIELLKSYEQELPETVFKQLEELPEKWKNMKKMAITVRQQVAPLQANEVALLRQRCSAFDDEQQQFQERFRKEAPFRFDSINPHQMLDAWHVEIQHMESTMATISKSADLFEVNVPDYKQLRQCRKEACQLKELWDTIGMVTSSIRAWEATSWRNISVEAMDSECKQFARHIRNLDKEFRSWDAFTGLESTVLNTLTSLRAVAELQNPAIRDRHWRQLMQATG----------VNFTMNQDTTLAHLLQLQLHHFEDEVRGIVDRAVKEMSMEKTLKELQTTWASMEFQYESHA-RTRVPLLQSDEDLIEVLEDNQVQLQNLMMSKYVAFFLEEVSSWQKKLSTADSVISIWFEVQRTWSHLESIFIGSEDIRAQLPQDSKRFEGIDSDFRELAYDAQKTPNVVEATN-KSGLYEKLEDIQSRLCLCEKALAEYLDTKRLSFPRFYFLSSSDLLDILSNGTAPQQVQRHLSKLFDNMAKMQFQLDASQNPTKTSLGMYSKE-EEYVAFS-------EACDCSGQVEIWLNRVLRHMKATVRHEMTEGVTAYEEKPRDQWLFDYPAQVALTCTQIWWTTEVGIAFARLEEGYESAMKDYYKKQVAQLKTLITMLIGPLSKGDRQKIMTICTIDVHARDVVAKMIAQKVDNAQAFLWLSQLRHRWDDE------------------AKHCFANICDAQFLYSYEYLGNTPRLVITPLTDRCYITLTQSLHLTMSGAPAGPAGTGKTETTKDLGRALGIMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVVAVQVKSIQDAIRDKKQRFSFLGEEISLDPSVGIFITMNPGYAGRTELPENLKALFRPCAMVVPDFELISEIMLVAEGFIEARLLARKFITLYRLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDPDRPEDQVLMRSLRDFNIPKIVTDDMPVFMGLIGDLFPALDVPRKRDLDFEAVVRKAIVDLKLQAEDNFVLKVVQLEELLAVRHSVFVVGGAGTGKSQVLRSLHKTYQIMRRRPVWTDLNPKAVTNDELFGIINPATREWKDGLFSSIMRELAIISHDGPKWILLDGDIDPMWIESLNTVMDDNKVLTLASNERIPLNPTMRLLFEISHLRTATPATVSRAGILYINPADLGWNPPVSSWIDQREVQTERANLTILFDKYLPTCLDTLRTRFKKIIPVPEQSMIQMLCYLLECLLTKEDIPAD-------------------------CPKEIYELYFVFAAIWAFGSAVIQDQLVDYRAEFSKWWLTEFKTVKFPSQGTVFDYYIDPETKKFEPWAKLIP----QFEFDPEMPLQACLVHTSETIRVCYFMERLMQWRRPVMLVGPAGSGK------------------------------------------SVLVGAKLSSLNPEEYMVKNVPFNYYTTSAMLQAVLEKPLEKKAGRNYGPPG-NRKLIYFIDDMNMPEVDAYGTVQPHTVIRQHLDYGHWYDRNKLSLKEIMNVQYISCMNPTAGSFTINPRLQRHFSVFALCFPGADALSSIYSTILTHHLK--FGNFPTTLQKSIPPLINLAVTFHQKIATTFLPTAIKFHYIFNLRDFANIFQGILFSS---------------VECVKSTQDLVKLYLHESSRVYRDKMVEEKDFNLFDKIQTEFLKKNFDDSEEVLKQTQNLNMYCHFANGIGEPKYMPVQSWDLLNQTLVEALESHNEVNAVMDLVLFEDAIRHICHINRILESPRGNALLVGVGGSGKQSLTKLAAFISSMDVFQITLRKGYQIPDFKVDLASLCLKAGVKNLSTVFLMTDAHVADERFLVLINDLLASGEIPDLYSDEEEENIINNVRNEVKSQGLMDSRENCWKFFIERVQRQLKVTLCFSPVGNKLRIRSRKFPAIVNCTAINWFHEWPQEALESVSLRFLQNT-KNIEPAVKQSISKFMAFVHISVNKTSQSYLTNEQRYNYTTPKSFLEFIRLYQSLLERNGKELQAKVERLENGLLKLHSTSAQVDDLKAKLATQEVELRHKNEDTDKLIQVVGVETSKVSREKAIADEEEQKVALIMLEVQQKQKDCEEDLAKAEPALTAAQAALNTLNKTNLTELKSFGSPPLAVSNVSAAVMVLMAPGGKVPKDRSWKAAKITMAKVDSFLDSLIHFDKENIHENCLKAIRPYLQDPAFNPEFVATKSYAAAGLCSWVINIVRFYEVFCDVEPKRQALNKATSDLTTAQEKLAAIKAKITHLNENLAKLTTKFEKATAEKLKCQQEAELTAGTISLANRLVGGLASENIRWAEAVQNFRQQERTLCGDILLTTAFISYLGFFTKKYRKSLMDGTWRPYLSQLKVPIPTTPTLDPLRMLTDDAEVAAWQNEGLPADRMSMENATILINCERWPLMVDPQLQGIKWIKNKYGEELRVTQIGQKGCLQTIERALEAGDVVLIENLEESIDPVLGPLLGREVIKKGRFIKIGDKECEFNPKFRLILHTKLANPHYQPELQAQATLINFTVTRDGLEDQLLAAVVSMERPDLEQLKSDLTKQQNGFKITLKTLEDNLLSRLSSASGNFLGETALVENLEVTKQTAADVEEKVQEAKLTEVKINEAREHYRPAAARASLLYFIMNDLSKIHPMYQFSLKAFSIVFQKAVEKAAPSESVTERVTNLIDSITFSVYQYTTRGLFECDKLTYLAQLTFQILLVNQEVNAAELDFLLRAPVQTGTPSPMEFLSHQAWGGIKALSSMEEFCNLDRDIEGSAKSWKKFVESECPEKEKFPQEWKNKTALQRLCMMRAMRPDRMTYAMRDFVEEKLGSKYVMGRALDFVTSFEESGPATPMFFILSPGVDPLKDVENQGKKLGYTFNNRNFHNVSLGQGQEVVAEAALDLAAKKG-HWVILQNIHLVAKWLSTLEKKLEELSEES----HPDFRVFISAEPAPSPEGHIIPQGILENSIKITNEPPTGMHANLHKALDNFTQDTLEMCSRETEFKTILFALCYFHAVVAERRKFGPQGWNRSYPFNTGDLTISVNVLYNFLEANTKVPYDDLRYLFGEIMYGGHITDDWDRRLCRTYLEEFIRPEMLEGELSLAPGFPLPGNMDYSGYHQYIDAELPPESPYLYGLHPNAEIGFLTQTSEKLFRTVLEMQPRDSQAGDGAGITREEKVKTFLEEILDRMTDEFNIAELMAKVEERTPYIVVALQECERMNILTREIQRSLRELHLGLQGELTMTSEMENLQNALYLDVVPESWARRAYPSTAGLAAWFLDLLNRIKELESWTGDFLMPSTVWLTGFFNPQSFLTAIMQSMARKNEWPLDQMALQCDVTKKNREEFRSPPREGAYIYGLFMEGACWDTQ----------------------------TGIIAEAKLKDLTPPMPVMFLKAIPADKQDCRSVYACPVYKTCQRGP-TYVWTFNLKTKENPSKWVLAGVALLLQI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NYC9-1", "uniprot_id": "DYH9_HUMAN", "id": "Q9NYC9-1", "name": "Dynein axonemal heavy chain 9", "aln": "MRLAEERAALAAENADGEPGA-------------DRRLRLLGTYVAMSLRPAAGAWERCAGSAEAEQLLQAFLGRD-------------------------------------------------AAEGPRPLLVVRPGPRGLAIRP--GLEVGPESGLAGAKALFFLRTGP--EPPGPDSFRGAVVCGDLPAAP-LEHLAALFSEVVLPVLANEKNRLNWPHMICEDVRRHAHSLQCDLSVILEQVKGKTLLPLPAGSEKMEFAD-SKSETVLD-SIDKSVIYAIESAVIKWSYQVQVVLKRES------SQPLLQGENP-------TPKVELEFWKSRYEDLKYIYNQLRTITVRGMAKLLDKLQSSYFPAFKAMYRDVVAALAEAQDIHVHLIPLQRHLEALENAEFPEVKPQLRPLLHVVCLIWATCKSYRSPGRLTVLLQEICNLLIQQASNYLSPEDLLRSEVEESQRKLQVVSDTLSFFKQEFQDRRENLHTYFKE-----------------NQEVKEWDFQSSLVFVR-LDGFLGQLHVVEGLLKTALDFHKLGKVEFSGVRGNALSQQVQQMHEEFQEMYRLLSGSSSDCLYLQS---TDFENDVSEFNQKVEDLDRRLGTIFIQAFDDAPGLEHAFKLLDIAGNLLERPLVARDTSDKYLVLIQMFNKDLDAVRMIYSQHVQEEAELGFS--PVHKNMPTVAGGLRWAQELRQRIQGP-FSNFGRITHPCMESA--------EGKRMQQKYEDMLSLLEKYETRLYEDWCRTVSEKSQYNLSQPLLKRDPETKEITINFNPQLISVLKEMSYLEPREMKH--------MPETAAAMFSSRDFYRQLVANLELMANWYNKVMKT-LLEVEFPLVEEELQNIDLRLRAAEETLNWKTEGICDYVTEITSSIHDLEQRIQKTKDNVEEIQNIMKTWVT-PIFKTKDGKRESLLSLDDRHDRMEKYYNLIKESGLKIHALVQENLGLFSADPT-----------------------SNIWKTYVNSIDNLLLNGFFLAIECSLKYLLENTECKA-----------------------------------------------GLTPIFEAQLSLAIPELVFYPSLESGVKGGFCDIVEGLITSIFRIPSLVPRLSPQNGSPHYQVDLDGI-----------------PDLANMRRTLMERVQR------------MMGLCCGYQSTFSQYSY--------------LYVEDRKEVLGQFLLYGHILTPE--EIEDHVEDGIPENPP--------LLSQFKVQIDSYETLYEEVCRLEPIKVFDGWMKIDIRPFKASLLNIIKRWSLLFKQHLVDHVTHSLANLDAFIKKSESGLLKKVEKGDFQGLVEIMGHLMAVKERQSNTDEMFEPLKQTIELLKTYEQELPETVFKQLEELPEKWNNIKKVAITVKQQVAPLQANEVTLLRQRCTAFDAEQQQFWEQFHKEAPFRFDSIHPHQMLDARHIEIQQMESTMASISESASLFEVNVPDYKQLRQCRKEVCQLKELWDTIGMVTSSIHAWETTPWRNINVEAMELECKQFARHIRNLDKEVRAWDAFTGLESTVWNTLSSLRAVAELQNPAIRERHWRQLMQATG----------VSFTMDQDTTLAHLLQLQLHHYEDEVRGIVDKAAKEMGMEKTLKELQTTWAGMEFQYEPHP-RTNVPLLCSDEDLIEVLEDNQVQLQNLVMSKYVAFFLEEVSGWQKKLSTVDAVISIWFEVQRTWTHLESIFTGSEDIRAQLPQDSKRFEGIDIDFKELAYDAQKIPNVVQTTN-KPGLYEKLEDIQGRLCLCEKALAEYLDTKRLAFPRFYFLSSSDLLDILSNGTAPQQVQRHLSKLFDNMAKMRFQLDASGEPTKTSLGMYSKE-EEYVAFS-------EPCDCSGQVEIWLNHVLGHMKATVRHEMTEGVTAYEEKPREQWLFDHPAQVALTCTQIWWTTEVGMAFARLEEGYESAMKDYYKKQVAQLKTLITMLIGQLSKGDRQKIMTICTIDVHARDVVAKMIAQKVDNAQAFLWLSQLRHRWDDE------------------VKHCFANICDAQFLYSYEYLGNTPRLVITPLTDRCYITLTQSLHLTMSGAPAGPAGTGKTETTKDLGRALGILVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVVAVQVKSIQDAIRDKKQWFSFLGEEISLNPSVGIFITMNPGYAGRTELPENLKSLFRPCAMVVPDFELICEIMLVAEGFIEAQSLARKFITLYQLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDPDRPEDQVLMRSLRDFNIPKIVTDDMPIFMGLIGDLFPALDVPRRRDPNFEALVRKAIVDLKLQAEDNFVLKVVQLEELLAVRHSVFVVGGAGTGKSQVLRSLHKTYQIMKRRPVWTDLNPKAVTNDELFGIINPATGEWKDGLFSSIMRELANITHDGPKWILLDGDIDPMWIESLNTVMDDNKVLTLASNERIPLNPTMKLLFEISHLRTATPATVSRAGILYINPADLGWNPPVSSWIEKREIQTERANLTILFDKYLPTCLDTLRTRFKKIIPIPEQSMVQMVCHLLECLLTTEDIPAD-------------------------CPKEIYEHYFVFAAIWAFGGAMVQDQLVDYRAEFSKWWLTEFKTVKFPSQGTIFDYYIDPETKKFEPWSKLVP----QFEFDPEMPLQACLVHTSETIRVCYFMERLMARQRPVMLVGTAGTGK------------------------------------------SVLVGAKLASLDPEAYLVKNVPFNYYTTSAMLQAVLEKPLEKKAGRNYGPPG-NKKLIYFIDDMNMPEVDAYGTVQPHTIIRQHLDYGHWYDRSKLSLKEITNVQYVSCMNPTAGSFTINPRLQRHFSVFVLSFPGADALSSIYSIILTQHLK--LGNFPASLQKSIPPLIDLALAFHQKIATTFLPTGIKFHYIFNLRDFANIFQGILFSS---------------VECVKSTWDLIRLYLHESNRVYRDKMVEEKDFDLFDKIQTEVLKKTFDDIEDPVEQTQSPNLYCHFANGIGEPKYMPVQSWELLTQTLVEALENHNEVNTVMDLVLFEDAMRHVCHINRILESPRGNALLVGVGGSGKQSLTRLAAFISSMDVFQITLRKGYQIQDFKMDLASLCLKAGVKNLNTVFLMTDAQVADERFLVLINDLLASGEIPDLYSDDEVENIISNVRNEVKSQGLVDNRENCWKFFIDRIRRQLKVTLCFSPVGNKLRVRSRKFPAIVNCTAIHWFHEWPQQALESVSLRFLQNT-EGIEPTVKQSISKFMAFVHTSVNQTSQSYLSNEQRYNYTTPKSFLEFIRLYQSLLHRHRKELKCKTERLENGLLKLHSTSAQVDDLKAKLAAQEVELKQKNEDADKLIQVVGVETDKVSREKAMADEEEQKVAVIMLEVKQKQKDCEEDLAKAEPALTAAQAALNTLNKTNLTELKSFGSPPLAVSNVSAAVMVLMAPRGRVPKDRSWKAAKVTMAKVDGFLDSLINFNKENIHENCLKAIRPYLQDPEFNPEFVATKSYAAAGLCSWVINIVRFYEVFCDVEPKRQALNKATADLTAAQEKLAAIKAKIAHLNENLAKLTARFEKATADKLKCQQEAEVTAVTISLANRLVGGLASENVRWADAVQNFKQQERTLCGDILLITAFISYLGFFTKKYRQSLLDRTWRPYLSQLKTPIPVTPALDPLRMLMDDADVAAWQNEGLPADRMSVENATILINCERWPLMVDPQLQGIKWIKNKYGEDLRVTQIGQKGYLQIIEQALEAGAVVLIENLEESIDPVLGPLLGREVIKKGRFIKIGDKECEYNPKFRLILHTKLANPHYQPELQAQATLINFTVTRDGLEDQLLAAVVSMERPDLEQLKSDLTKQQNGFKITLKTLEDSLLSRLSSASGNFLGETVLVENLEITKQTAAEVEKKVQEAKVTEVKINEAREHYRPAAARASLLYFIMNDLSKIHPMYQFSLKAFSIVFQKAVERAAPDESLRERVANLIDSITFSVYQYTIRGLFECDKLTYLAQLTFQILLMNREVNAVELDFLLRSPVQTGTASPVEFLSHQAWGAVKVLSSMEEFSNLDRDIEGSAKSWKKFVESECPEKEKLPQEWKNKTALQRLCMLRAMRPDRMTYALRDFVEEKLGSKYVVGRALDFATSFEESGPATPMFFILSPGVDPLKDVESQGRKLGYTFNNQNFHNVSLGQGQEVVAEAALDLAAKKG-HWVILQNIHLVAKWLSTLEKKLEEHSENS----HPEFRVFMSAEPAPSPEGHIIPQGILENSIKITNEPPTGMHANLHKALDNFTQDTLEMCSRETEFKSILFALCYFHAVVAERRKFGPQGWNRSYPFNTGDLTISVNVLYNFLEANAKVPYDDLRYLFGEIMYGGHITDDWDRRLCRTYLGEFIRPEMLEGELSLAPGFPLPGNMDYNGYHQYIDAELPPESPYLYGLHPNAEIGFLTQTSEKLFRTVLELQPRDSQARDGAGATREEKVKALLEEILERVTDEFNIPELMAKVEERTPYIVVAFQECGRMNILTREIQRSLRELELGLKGELTMTSHMENLQNALYFDMVPESWARRAYPSTAGLAAWFPDLLNRIKELEAWTGDFTMPSTVWLTGFFNPQSFLTAIMQSTARKNEWPLDQMALQCDMTKKNREEFRSPPREGAYIHGLFMEGACWDTQ----------------------------AGIITEAKLKDLTPPMPVMFIKAIPADKQDCRSVYSCPVYKTSQRGP-TYVWTFNLKTKENPSKWVLAGVALLLQI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13A7H0-1", "uniprot_id": "A0AB13A7H0_DANRE", "id": "A0AB13A7H0-1", "name": "Dynein axonemal heavy chain 17", "aln": "---MEEQEPLITD----------------------KRLDYLENCVLKALNVKPERWERCVSAEEQRRVIQEFLDQS-------------------------------------------------EHS---TLSVSVNSAGQLVPAL--GLSAAVKS-----KAVFFVKRGK--GALTADKMKTQLFSGDMCYSP-LEQFSVLVDKVVEPVLSNLNNQRDFPKVVSQDLMRHIHALQNNVFVTAGQIKGKTHLPVPLGFKQFEQCS-QQLDKRFH-VVDKSLIHSMETVVIDWSHQVYKVLKKDS------SEPLLEGRNP-------TPHAEIQFWRNRLADLQGIQQQLQSSKVLTLAELLLAVDSSYYPAFAKMIQDVMEAHNESKNITTFLKPLERLIEDLENADFTELKAKIPPLMHTVCLIWANCRYYSKPARVIVLLQEICNLLIQQARSFLNPDDILKGDVLESLLRVQAAVDLLTHFKNTYEDRRANLSHYQKN-----------------EDPVKPWDFSPLMVFVG-LDHFMKRLRTIETVLLTVMDMMRLEKIEFGGIQGKSLSQIVQRLHEDFLQTYKSFSEKPYDCLDVNN---MEFESDFAEFQLTVDDTNRRLGAIFCNAFDDASGLEHSFKVLDMFGRLLEQPLIAAEAQARYPILIKLFDKQLEDCKTIFKKQMQMEETRGYS--PVSKNMPAVSGGLKFVQELQERIQTL-YNNFRFINHPCMESV--------DAKEMMQKYDELMRQLKQYSSKLYDIWTSSVAEKSQFNLNKPLISREPRSRLLSVNFSPQLVSVLREVKYLEARQAEI--------IPDAAAEIYSSRELLWQYVANLELTTGWYNKIISS-VLDVEMPLVQGQLTDIDNKLKGAQENLCWISEGIWEYIQDVREAVSDLEQRLRRTKDNVEEMQSLMKSWAT-PLHDRKEGKKEMLLNLEERSERVERTYSHIRSSGARIHLLLQENLHLFKADPS-----------------------SPQWKIYVDYVDEMVIDGFFNAIESTLKFFMENTDADA-----------------------------------------------GLEPLFEAQLRLQVPDLVFQPSLELRSSDSLHELVEGLLRDVFKTSTLVPRLAKHSGFPDYQDDMEDM-----------------EELVQTRQHVMQRVKR------------IMMKCCEYRNSLERYAY--------------LYVDDRKEFMRQFLLYGHVLTSQ--EIEEHAEHGVPESPP--------TLERFRQQVDSYERLYEELQRMEPVMVFERWMRVDARAFKSALLNTVKKWSLMFKQHLIDHVTNSLSDLEEFIRLTEAGLGQKVEEGDYRGLVEIMGFLMAVKERQSSTDEMFEPLQQTIDLLKTYEQELPDVVYKQLEVLPEKWNNMKKQAVQVKQHVAPLQAAEVANLRRRCAAFDVEQHTFRETFRKKHFFRFDSVNVHEQLDTTHTQIQELESLMAGLTESANLFEVGVPDYRQLKQCRRELPLLKELWDQALAVRSCLEAWQRTPWSQINVDDMETECKRFSKELRLLDKEARAWDVFNGLDGMVKNTLTSLRAVAELQNPAIRPRHWQQLMAATG----------VQFTMDQDTTLADLLRLNLHHFEEEVRGIVDRAVKEMGMEKVLGELDATWTSMSFEFEAHP-RTQVPLLKSSEELIETLEDNQVQLQNLMSSKYISFFLEEVSSWQRKLSVTDSVISIWFEVQRTWCHLESIFIGSDDIRSQLPEDSKRFEGIDGDFRELTLDARQTPNVVEATN-KPGLYSKLEDIQSRLALCEKALSEYLDTKRLAFPRFYFISSADLLDILSSGTDPHQVQKHLSKLFDNMAKLQFQAGEDGGLQKTALGMFSKE-DEHVPFS-------HACDCTGQVEVWLNRVMDSMRATVRHEMTEAVAAYEEKPREQWLFDYPAQVALTCTQIWWTTDVGMAFSRLEEGYENAMKEYYKKQVNQLNTLITMLIGQLTPGDRQKVMTICTIDVHARDVVDKIITQKVENSQAFLWLSQLRHRWGDR------------------EKHCFANICDAQFLYSYEYLGNTPRLVITPLTDRCYITLTQSLHLVMSGAPAGPAGTGKTETTKDLGRALGIMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVVAVQVKSIQDAIRDKKQRFNFMGEDVCLVPSVGIFITMNPGYAGRTELPENLKALFRPCAMVVPDFELICEIMLVAEGFIEARLLARKFITLYQLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDPGRAEDQVLMRALRDFNVPKIVTDDMPVFMGLIGDLFPALDVPRKRDMDFEKLVRQSVLELKLQAEDNFVLKVVQLEELLAVRHSVFVVGNAGTGKSQVLKSLHRTYQNMQRRAVWSDLNPKAVTNDELFGIINPATREWRDGLFSNIMRELANITHSGPKWIVLDGDIDPMWIESLNTVMDDNKVLTLASNERIPLNPSMRLLFEISHLRTATPATVSRAGILYINPADLGWNPLVSSWIDSREVQSEKANLTILFDKYLPSCLDTLRVRFKKIIPVPEQSQVQMLCRLLECLLVPEHTPPD-------------------------SHKDLYELYFVFAAVWAFGGTMFQDQLLDYRLEFSKWWVTEFKSVKFPAQGSVFDYYIDPDSKKFEPWSKMVP----KFEMDPEIPLQACLVHTTETIRVRYFLDRLLERRRPLMLVGNAGTGK------------------------------------------SVLVGDKLASLDAEKYTIKNVPFNYYTSSAMLQAVLEKPLEKKAGRNYGPPG-SKRLVYFIDDMNMPEVDEYGTVQPHTLIRQHMDYSHWYDRSKLQLKEIHNVQYVSCMNPTAGSFTINPRLQRHFCVFALSFPGADALHSIYCSILSQHVR--GESFSVSVQKSCSQLVDLALALHQRITTAFLPTAIKFHYIFNLRDLSNIFQGILFCG---------------SECLRTPQDLLKIYLHESSRVYRDKMLEERDFQLFDKLQEDTVKKIYEDVDALLQETRVMNLFCHFSAGVGEPRYLPVPTWSSLAHTLQEALEAHNELNPAMSLVLFEDAMAHICRISRILESPRGNALLVGVGGSGKQSLTRLAAFISSLDVFQITLKKGYSIPDLKSDLGSLYIKAGVKNIGTVLLMTDAQVADEKFLVLVNDLLASGEIPDLFPDDEVENIIGSLRNEVRAQGLMDTRDNCWRFFIERVRRQLKVALCFSPVGNKLRVRSRKFPAIVNCTAIDWFHEWPQEALESVSLRFLQDL-EHIQPELKEPVSKFMAYVHVSVNKTSRDYLLNERRYNYTTPKSFLEQIKLYGNLLALKKRDLQSKMERLENGLEKLNSTTAQVDDLKAKLAAQEVELKLKNESADRLIQVVGVETEKVERERAVADQEEQKVACIAEEVMRKQRDCEEDLAKAEPALIAAQEALNTLNKNNLTELKSFGAPVSAVTNVTAAVMVLTAPGGRVPKDRSWKSAKVMMAKVDAFLEALITFKKENIHENCLKAIQPYLQDPEFQPELVASKSNAAAGLCSWVINIVRFYEVYCEVEPKRQALSKANTDLATAQEKLAVIKAKITLLNENLAKLTAKFEKATADKLRCQQEAETTERTIALANRLVGGLSLEKVRWAEAVQVFQQQERTLCGDVLLITAFVSYLGYFTKHYRLQLMDHCWRPYLSQLQVPVTEG--LDPLSMLTDDADRAVWQNEGLPADRMSTENATILSSCERWPLMVDPQLQGVQWIRNRYAERLRIIRIGQRGYLDSIERALSVGEVVLIENLEESVDPVLGPLLGRETIKKGRCIKIGDKECEYNPSFRLILHTKLANPHYQPELQAQCTLVNFTVTRDGLEDQLLAAVVSMERPDLEELKLNLTKQQNGFKITLKTLEDNLLSRLSSASGNFLGDIELVENLETTKCTAAEIERKVKEAKGTETDINDAREHYRPAAARASLLYFIMNDLNKIHPMYQFSLKAFSVVFQKAVQKAEPDESLKQRVCNLIDSITWCVFQYTTRGLFECDKLTYTAQLAFQVLLMNREISPHELDFLLRYPVQPGLISPVDFLSNHSWGGIKALSTMEEFHNLDRDIEGSAKRWKKFSESECPEKEKFPQEWKSKTALQRLCMMRALRPDRMTYAVRDFVEEKLGSAYVTGRSLDFSVSYEESGSATPMFFILSPGVDPLKDVEKHGRKLGYTFDNRNFHNVSLGQGQEVVAEQALDTAAREG-HWVILQNIHLVAKWLGSLEKKLEQHAEGS----HQDFRVFMSAEPSSSPDGHIIPQGILENAIKITNEPPTGMHANLHKALDNFTQDTLEMCVRENEFKSILFALCYFHAVVAERRKFGPQGWNRVYPFNTGDLTISVNVLYNYLEANSKVPFDDLRYLFGEIMYGGHITDDWDRRLCRAYLQEFIRPEMMEGELMLAPGFRLPTNTDYSGYHQYIDAALPPESPYLYGLHPNAEIGFLTQTSEKLFRTVLEMQPRDGGAGDGAAGARDEKVKAALDEILEKLPEEFNMSELMAKVEERSPYVVVALQECERMNTLTQEIKRSLRELNLGLKGELTMSSDMESLQSALYLDQVPDSWTRRAYPSLCGLAVWFSDLQSRIRELESWSSDFCLPAAVWLAGFFNPQSFLTAIMQAAARRNQWPLDRMSLQCDVTKKSREEFSSAPREGAYIHGLYMEGARWDTQ----------------------------AGVVTDARLKELTPALPVLFIKAVPVDKQDTRSLYQCPVYKTRQRGH-THVWTFSLKTKDNPAKWTLAGVALLLQI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KHJ4-1", "uniprot_id": "A0A0B4KHJ4_DROME", "id": "A0A0B4KHJ4-1", "name": "", "aln": "---MEPSTSAEAAAAAAAGGP-------------DPRLELMGSFVIKSLKLKPEKWTRVVTVEEHKGIIKEFLDR----------------------------------------------------NTPVVLIIILTPAAQLVPST--TFPLSQLKS----KGVYFIKRYA--LPIPREDCGNFIIYGDLATRT-IDQLSALVEEVLVPLLSNEDNYRNWPIMVAQDVQKHVHSLKSTVHQVKGQVSGETILAMPVGVEKIVKAAKELVETEQC-QFDLYLKSAIEGVVIKWATQIHEVIKESP------SNAFANGQNP-------TPHTEFTFWNNRLKNLSFIYDQLRNERIRAMALILEYSMSAYHPCFQTLFKNVVTALAEAKDITLYLNPLKRPLQHLEEIDFAECKPLLIPFMNTVGILWGNSRYYCQSAKITVLLQEICNLIIHQAKRYLDPSSIFHSDIDEAMQRLTLSIQILKFFRELFDYYKERLATFFTEP---------------EERPPILWTFHPNSVFKR-FNAFLERLTTIQWFFFTVIEFLKLEKVEIGGLRGRQLSTRITDVYVEFNQYFTAFASKSYDVLDPDD---HEFDEDFKGFQTRILELDMKLAAILCQAFDDCHNLESIFKLISIVGSVLDRPKIKEEFTQRYAEIVRMLDDEMTICESIYDKQMELKKVGDNL--YPNYNCPPVAAFIRWCHQLETRITAP-VKNFKALQHEITKTE--------KSQEIVERYEILMVKLGSCKTQFFDDWAGQLDGQIEENLKKSLIARDRRHNSLILNFSAALFSILREVHYMQQMKIEG--------IPQIAIDFAEKSDVFRSYTLNLEKTIDWYNSIQEG-SSPVELRLIEPEIKMIDDLVEIGVNQLVWNSSDILSYLDKLRKPVAALQNRMDHTQGNLRQIRKIMGVWAKQPLFERRDCKKDTVLSIDERPDRTSKRYAEIQAASIEIHKLLQDNMLQFDMESKQ---------------------DDAVWLSYVDFVDNIVYENILKTVGVSVGYLAENMDPEN-----------------------------------------------NYAPLFESRLELVEPNLVFVPSLDPEDPMGFNNMLIELMRDIMKMGSLIKRLKPNE-KRNYVEMIKEN-----------------QDIIDMRREILNGVDL------------VMEEASRFCRQFERYSY--------------LWLDDREECMEYFLEYGRMLDPD--EIELILINDPNQPPPQPCQ---PTIEAFREQIDNYESLFNEIEDIGPFQVFSSWFQVDVRPFRQALLNTVCKWGNMFKEHLVTTVTSSLMNLSHFIRKADEGLLQTVKEKDYEGLVSIMAYLMQVKERAAKTDEMFEPMQETIQLLKYYDMDIPEEVNVLLQELPEQWANTKKIASTVKQQVSPLQATEVVSIRNKIALFESHIQLFREVFKTYDFFRFDCYKPYLLMDRINDDMFLCESEMRDIQESGSLFEVNIPEFKVLKQCRKELRMLKQLWDYVNIVATSIDDWKTTPWRKVDVENMDIECKKFAKDIRLLDKEMRPWDTFINLESTVKNMLTSLRAVGELQNPAIRERHWNQLMNSTKSLAALPKEVTVKFIMDHETTLAELLGLNLHECEEEVKNIVDKAVKEMSMEKILRDLNTTWTVMEFDHELHP-RTGCNLLKASEELIETLEDNQVCLQNLITSKYIAHFLEEVSTWQNKLMIADQVITVWFEVQRTWTHLESIFMSSEDIRKQLPVDSDRFDNIDAEFRVLMDEMSVSSNVVASTN-RSGLIERLEHLQKELTLCEKALAEYLETKRLAFPRFYFVSSADLLDVLSNGIQPEMVTKHLTKLFDSIARLKFNRDESNE-INTASGMYAKD-GEYVEFN-------ELASIRGPVEVWLNRIQAAMRASLRHYVMEAVIAYEEKQREQWLFDYPAQVSLCGSQIWWSTEVNIAFSRLEEGYDNAIKDYYKKQISQLSLLITLLLGELSKGDRQKIMTICTIDVHSRDVVAKMIQAKLDSGSAFMWQSQLRHRFDDV------------------EKDCFANICDAEFQYCHEYLGNTPRLVITPLTDRCYITLTQSLHLVMGGAPAGPAGTGKTETTKDLGRAIGISVYVFNCSEQMDYQSCGNIYKGLAQTGAWGCFDEFNRITVEVLSVVAVQVKSVQDAIRDKKDKFNFMGEMISCVPTVGIFITMNPGYAGRTELPENLKALFRPCAMVVPDFELICEIMLVAEGFQDARVLARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDPGRPEEEVLMRALRDFNIPKIITDDMPVFMGLISDLFPALDVPRKRDQDFERTVKQAASDLLLQPEDNFILKVVQLEELLEVRHSVFIVGNAGTGKTQVWKTLLRTYQNIKRKPIFNDLNPKAVTNDELFGIINPATREWKDGLFSVLMRDQANITGDQPKWIVLDGDIDPMWIESLNTVMDDNKVLTLASNERIALTPSMRLLFEISNLRTATPATVSRAGILYINPQDLGWNPYVTSWVETRKIPAEKSNLVMLFDKYIPPSLETIRVRFKKITPVAEMAHIQMLCHLLNCFLIPANTPAD-------------------------CPKEWHELYFVFACIWAFGSAMFQDQAIDYRVEFSKWWVNEFKTVKFPPGGTVFDYFLDSETKTFLPWTEKIP----KFELDSDLPLQAVIVHTSESIRLRFFLDLLMDKKHPVMLVGNAGCGK------------------------------------------TVLVNEKLQSLS-ENYAVTTIPFNYYTTSEMLQKILEKPLEKKAGRNYGPPG-NKLLCYFVDDINMPEVDAYGTVQPHTLMRQHLDYGHWYDRNKLTLKDIHNCQYVACMNPTSGSFTINPRLQRHFCVLAVSFPGPESITVMYSSILAQHFANAEQKFTPIVTRMTPNIVAATIALHNKCLQVFLPTAIKSHYIFNLRDISNVFQGLLFSS---------------TECLTGSTDLIRLWQHETQRVYSDKLTDDKDIDSFTKMQHDIVKKSFEEIDESVIFDK-PNIYCHFAGGIGDPKYMPIKGWPELHKLLQEAMSSYNDLVAAMNLVLFEDAMMHVCRINRILESPRGSALLVGVGGSGKQSLARLAAFISSLEVVQIQLKKGYGVNDLKNEFSGLYLKAGLKNVGIMFLMTDAQIPSEDFLVLINDMLATGEIPDLFPDDEIENIIAGVRNEVKGAGLVDTRENCWKFFIDRVRKQLKIVLCFSPVGSTLRVRSRKFPAIINATSINWFHEWPQEALISVAMNFLAQN-KVLPENHRDSVAKFMAYVHTSVNTTSKVYLQNERRYNYTTPKSYLEQINLYIKLLNHKNEDLQSKIERLENGLEKLRSTALQVADLKVKLAVQEIELKEKNEAADALIEIVGIETEKVQTEKAVADEEEMKVALIADEVSKKQRDCEEDLLKAEPALMAAQDALNTLNKANLTELKSFGSPPGAVTNVTAAVMVLLSQGGKVPKDRSWKAAKIAMAKVDTFLDSLINYDKENIHPEITKAIQPYLKDPEFEPEFVRSKSGAAAGLCAWVINIIKFYEVYCDVEPKRKALAAANAELAAAQDKLAGIKRKVMSLEEQLGKLTADFEKATADKLRCQQEADATQATIALANRLVGGLASENVRWAEAVNNFVKQGITLPGDILLITAFISYVGCFTKGFRIDLLLKMWTPFLKSIDPPIPTTENLDPLSLLTDDTTIAIWTNEGLPSDRMSIENATILSNSDRWPLMIDPQLQGVKWIKQKYGEDLKVIRLGQRSYLDIIEKSINAGCNVLIENIDENLDPVLDSLLGRNLIKKGKAIKIGDKEIEYNSNFRLILHTKLANPHYKPEMQAQTTLINFTVTRDGLEDQLLAEVVKAERPDLEELKADLTKQQNDFKIMLKKLEDDLLSRLSSAGENILGDTALVENLETTKSTASEIEQKVAEAKITSKEIDKAREYYRPAAARASLLYFILNELNTINPIYQFSLKAFSVVFQKAIAKAEPGDTLDLRVSNLIDCITYSVFQYTSRGLFECDKLIFASQMTFQILLMNEEVTSAELDFLLRFPIKPHVTSPVDFLTNQSWGGICSLASKDEFRNLDRDIETSSKRWKKLVESELPEKEKFPQEWKNKTALQRLCMIRALRPDRMTYALADFIEEKLGSKYVESRAMEFAKSYEEASPSTPIFFILSPGVNPLKDVEALGKQMGFSMDLGNFHNVSLGQGQEAIAEAAMDTAAKHG-HWVVLQNIHLVRKWLPVLEKKLEYYAEDS----HPDYRMFLSAEPASTPSAHIIPQGILESSIKITNEPPTGMLANLHKALDNFTQETLEMSGKEAEFKAILFSLCYFHAVVAERRKFGPQGWNKIYPFNVGDLNISVSVLYNYLEANAKVPWEDLRYLFGEIMYGGHITDDWDRRLCITYLEEYMQPDLVDGELFLAPSFPAPPNTDYQGYHTYVDEMMPAESPYLYGLHPNAEIGFLTTRAENIFRTVFEMQPRDAGAGGGATVTREDKVKQIVDEIIEKLPEEFNMVEIMNKVEERTPYVIVAFQECERMNFLTSEMKRSLKELDLGLKGELTITSDMEVLENSLFLDQVPPIWTQRAYPSLLGLNNWFIDLCLRLRELETWSTDFVLPSCVWLAGFFNPQSLLTAIMQSTARRNDLPLDKMCLQCDVTKKQKEEFTTAPRDGCCVHGIFMEGARWDIQ----------------------------QGIIMESRLKELYPSMPVINIRAITQDKQDLRNMYECPVYKTRTRGPTTYVSNLNLKTKDKPGKWILAGVALLLQT", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q0KI05-1", "uniprot_id": "Q0KI05_DROME", "id": "Q0KI05-1", "name": "", "aln": "---MSDAAAMASSDEEGLPAGSTSGRQRVQRDYSDARLERVAAYTTTTMRLKPDKWTKMMACDDLRRIVVEWQHGHRRVLVMTLSPGGDLVPRSCLSDLYLPYSVQSARGSIPSAMLPAEDEAMATVTAAVSAVVSATPGALLIPLPPASSSFTTLDGVPRGKCAYFVRRNTSDGPLTASNFAESVLYGDFPVHSKIETMSLLFDDVLQPLLEQAQS--QWPAIVRKDLQARIKEVRNTLTEIKGKTNNRTILSLLVSPTIVEEVFAHVSQGHLRPALDPKFRNLLEEMFINWTTQMHDIVLERSECQPLGSTTQSAGHQPKYITLVSLPAQEIGFWTNRKLNLQNIYEQLRESTHKTLAQILERIESVYYEPYATAFRKLVAAWLEAQDVSLWLQPLLRQTAAFNSVQFSNGHDLVAPLVHIVHLVWSNARYYRSTQRMSVLLRCICNMLVHRAAEDLELQLLFQGDADEGLLKINRTIAVLELFKQRMLDYKERYAGSQVLLPALSEGAAAVASSPSPDDQQQLWRFCHEDVFGQTLDGFSLQLLELRQVFEAAVQFQQLEKLEVGGLRGKILTERVREIFGEFKVLFEQWSNVDIDLTATVASKWKCFRREQTLFFSRMQLLEQKLATVLLQAFEQCHSWMHLLRLTLMFGSLLQREAVRPELARVLPHILFIYDTEMEQLEDSVGEVLLGYEIRGLAALPLANNFPPIANAMMWLEQHISRCDEFGAKELSQLVEQLLKEKSELQTLPIQWNSLLSRRNILTTKLSNLQMKIWISWHECVDKLIIQGLDESVLSRSQDLSQLHLNFSQVLFTLLKETKYLLALQATGSLSGDLFQLPEPLLTLYGHRDAYWERRIRLIKIGEFYNGIRSGECAAAELQLIRNDLASIDEHVEVACQQLTWRN-YNDELVAGIFEQSRDLFARLQQSHGNLDAILASMRRWSREPLHQRSLYGRN-LLDLRHQQDRVRLRLLQCDETKMLLNRLLIANFCLFFNYESQEFQLYSRDLSVQEFIREFPEEQRRQYNKYLASVDELICREVREAMRISLEYLYKEMTATATATTTPTAPPVDPGCSAGMARLVLQQITTPQATSTAGAGASGAPPTANDAPLFEVKLELTETEIRFSPAFDASVENNFQQIVEQLLLDIKQTCDCMPRIVADNAPSEDDEDDDTATVDYEQELRWEPREDRAQELQERKKKDLELEQEQGDPKPQAVQFNLLAAAKAYSQKMECTADGLEMLERAIRDALADTVAAASAYAAKFQAYAFLWTQQSSEVLAACMQTAREQTHHVSAGGYAIMETFKKEIENYNEVHDAIDQCENRECINGWLALDIKPLKYGLLNLACKWSHMCKKWLLRYVQGTLKELNAFIARGFETLQLHIARQDFATLLRVLAIMSEIREREPYADNVFKPLKEIMGLLKTYNVEFEPQLLRGIEQLPQQWQQLKHSSTVKQEALQDTRFHQQQRVTALIGLHTCHLQHYARQFQKMPFFRVPCPQVYDVCDEVYLRLHRFRRQQRLYTRWARLLDIQPPDPATLQFCEVELRRVKQLWDFVRVIESCIVAWHATPWLLIDTDDMEHECKKFTRDLRTLDKCIREWAPYVHIVGVLRELVASLRAITELQNPAITERHWMELMQLTK----------LSYKCNKSTRLAQLLTLQLQHHEEDIKNTVDRAIKEMTVTKVLDEIKATWAHLEFELEQHHTRPHIQLLKVSEELIETLDDNQMQLQNISTSKHIEYLLDKLTHWQKVLGGIDTLIVNWFEVQRKWIYLECIFIGSADIRAQLPADAANFERIDEDFTALLAKVQEVRVVMQVVLRHDDVLAQLLQLQHRLAVCEKALNDYLETKRLAFPRFYFISAADLLDILSNGNNPQVIDRHLIKLFDSILRLQYETN-----TPNALGMHSKENDEYVPFVSFDPDQPAFIVCGGRVELWLRAIIQQMRSTLHELFRRALRVFGEKPRELWLYDWPAQVALCCSQISWTADVNRSFGCMEEGYEGVMKELHKRQIAQLNALINLLLGELSPGDRQKIMTICTIDVHSRDVVGKIIASKVDNSLAFQWQSQLRHRWDDDQAGSSSGRASTAISCGGGDEDCFANICDAEFRYAYEYLGNTSRLVITPLTDRCYITLTQSLRLRLAGATAGPAGTGKTETTKDLGRALGVMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRICVEVLSVVAVQVKTIQEAIKMHKTQFIFMGERISLEPSVGIFITMNPGYAGRTELPENLKTLFRPCAMIVPDFALICEIMLMAEGFQDARLLARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAGTLKRDDHSRPEDQVLMRALRDFNIPKIVTEDVPIFMGLIGDLFPALDVPRKRVFEFEKTIRRAVNEIKLQPEEGFLMKVVQLQELLDVRHSVFIVGNAGTGKTKIWQTLRETYRIQKLKPVCHVLNPKALSNDELFGIVNPTTREWKDGLFSSIMREQANMPPGNPKWIVLDGDIDPMWIESLNTLMDDNKILTLASNERISLKREMRLLFEVGHLKAATPATVSRAGILYINPQDLGWSPYVSSWLETRVDMIERGILNALFEKYFP-CLMQRQRDFRRITPITDMAMIQMTCHLLECLLDSDEGNADGRGRGSATGGAANPHSLHHGELSHEAMVMALETIFVYATVWSFGSALSQDVIIDWHREFHKWWIGEFKDIKLPSQGTVFDYQLNVQTLKFQPWSELAAHQSLEGQIDSETPLQNVLISTAETIRLAYFLKLLIDRNLACMLVGNSGCGKGAIFRQLFGQYANDQELLEVAVSAATAGDSSHQQQSGNPAGAVVVRRKASSSATPLLTTVQATHFNFYTSSEIFQKMLDRPLEKKSGRCYAPSGPKRRLIYFVNDLNMPEVDAYGTVQPHTIMRQFMDYRQWYDRQRLQLKDIRHCQFAACMNPTAGSFTIDPRLQRHFCVFSVAPPGEDTLHHIYGSILSSHLESPSQGFTKEIRSIGSLLVRVGIALHRRVEYAFLPTALKFHYLFNLRDLTGIYQGLMNSVGAPASAGGGGASGFGGTICSRPSELMRLYVHEAFRVYHDRLVDPYDIKSFKSSIRDIFKKDFEDFDEDFVFAE-PLIYSHFAQSLVDQKYMPLKSWDSLYQLLIEAQASYNEVVGYMNLVLFEDAMIHVCRINRILESPRGNALLIGVGGSGKQTLARLAAFISSLNVSQIQIKRGFGLLDMREEIGNLYMKVGLKNLASVFLISDAQIPDESILMLINDLLASGEIPELFNDDQLDTITNGIRNEVKQSGTLDTKENCWRYFVEKVRRLLKVVLCFSPVGQTLRVRARKFPAIISRTAIDWFHEWPKSALESVSQKFLNEINGILEPALVPPIGCFMAYVHGTVNQISRIYLQNEKRYNYTTPKTFLEYIFLYRKLLVDKNGEFAERIARLQSGMSKLAECARQVDTLKHQLAIQEVQLAAKNAAADKLIVIVSAESEKVKRERYIASEEEKRVRIIEEDVSIKTKMCEEDLRQAEPALVAAQAALNTLNKNNLTELKSFGSPPKAVVNVCAAVMVLLASNGKIPRDRSWKASKLMMVRVDQFLNDLLNYNKDNIHPNIIETLQEYLKDPEFNPDKVVQKSVAAAGLCAWVINLHRYHQVFLIVGPKQQALQDSHQELLEARERLQYLKAKINNLEAKLAEIQAEFENAVGEKQRCQREADKTAFTIDLAHRLVNGLANENVRWKESVQSLLAKIGTLPGDILLISSFLSYVGCFTRRYREELQHKMWLPNFRKIDPHIPHTEGVDTLALFSDDAQIAAWNNEGLPMDRMSTENATILQYSTRWPLMIDPQLQGIKWIKNRFGTDLVVLRLRQKGFLEALEKSISQGDTVLIEQIEESMDTVLEPLLSRALIKKGRYLRIGDKEIEFHASFRLILHTKMANPHYKPEMQAQTTLINFTVTPDGLEEQLLAEVVKIERPDLEQMKTEVTVQQNKFKISLKALEDELLARLASSGENVLDDHALVINLENTKRTVDEIEAKVREARVTTLQIDDTRNIYRSAAKRAAILYFVLTDLSRINPIYKFSLKSFMNVFRQAIAMAAESKNYEKRVLHLVESITLQTYRYTLRGLFEADKLTFTSHMTLRILIAAEQVAKDETDFLLRFPHDPTTLSPLDFVGRSAWGGIKSLTLIEHFYGIDKDMENYTKRWRKFMASDTPEREQFPGEWKHRTPLQKLCIIRSLRPDRMTYAMRQFVEQTMGRSYAEIQTPPFGAIFQELNAATPAFFILSPGVDPIRDVERYGQRQGFHSESDTLVNISLGQGQELLAEQAIIGALESGQQWVILQNIHLVVNWLPTLEKLIERIVLQSESKGESNFRLFISAEPAPDPQYHVIPQGILESSLKVVNEPPSGMAANLHKAWDNFSQDALETCTQEAEFKSILFALCYFHAVAGERRKFGPQGWNKVYPFNIGDLTISSNVLHNYLEGSNRIPWEDLRYLFGEIMYGGHITDDWDRRLCQTYLEELLQQDLIDGDFELCPGFPAPPNLDFEGYHSYITEMLPEESPLLYGLHPNAEIGFLTTASEQLLRTIFELQPRESELSSHCGAPREELVKIMIDDFLDKLQDEFNLQALLNRVERKTPFVVVALQECERMNALIREIKRSLRELMLGLRGELTITQEMERLDHAIFYDHVPAAWARLAYPSMLGLQSWFADLLHRIKELAGWLNDFKLPCAIWLGGLFNPQSFLTAIMQESARKHDLPLDRMLISCDVTKKQKDDVTLPPMEGAFVHDLYMDGASWDCQ----------------------------LNSIVALRPKEMLCAMPVIYIKSIVQEKQELQRVYECPLYKTRSRGN-TYVWTFNLKTRERPSRWILGGVALLLQP", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . ** : . ::. . * : : :: : : * * :*:: . . :. **: . :: :: *...*: *:* : .. ::* :: :*: : : :: : : ...* *.: . . : .* :* .*.*: *: :: . . * . *.:* * *: ** .* :*. * :** :* :* * * : :.: * *:::: * ** : ::. :*.: : : *::: * ::*...: * .. :: ***: ***:::::* *. . :::.: *. :: * *:: : . : * * ** :: * :: :. .: :.::: .* *:*..*::*. *: : :. :* : * * : * : : :*.::: :**:: ::: : * ::.: : : :: : . :: . : : . * *.:: : : .: * :: : . : . : : .: : : * . . ::: * : .*. .:: *. : :**. *.::*:* *: : :*: : : . .* :** : .*: *:. :: ** :. . : * * . . : . * *: :::.*: : * * *:.. :: *.: .: : : :: *: *: * : *: :*.:: . :: :: :: :: . *:** :* * .:: * *::: .: ::: *: : : *: .. . . :: : :: . :: . : :. : : . * *. : : *: . : . : *: :::.*: :.: : :. *: :* :.:: .*** :*. : *: *: * :* :*. ** * : . *: *: ::. : ::** . :*::*:*::: : *** *: :: : :: **::* : *: : :: : : : : . . : : . *:. **. . : : * : . . . *::: *: *: *. * :*:*** : :.: *. *.* :..: *: ***:*::.:* *** * * : : . : : ::****: ******* *** :** * :.: ::.* **.** *:*:. *::::. **:* *** : * * ::.:**: :.*: * * *. ** .*:***.*:***: ***: **:: .:*:::: **. * * :* ******.* :**.** .* *** *** *: .*: ** :* * . *: . : .: :* .:* .* :***** :**:****:******:*::****:**.* *. : :** ****.: ::::: . .: **.:*: *:* * * **:**. : *:::::. . ..: .: ** *: **:* ****:* :** *:::*. :*. :****:..:*: :*:*: **. **.:*:* *: *****:*********:**** *:* *::.. ** * ******:.* :.********:* *.:******.*******************:* :.**.******************:*: ************:************************ ************::*:**: :* * *:** :. *:**********************:*******:**** **.****:**** :*: ********* ***************************:***.* .*.*::****:*****:***:*:*:*:*****.**********:* :** :::: :: **.*:.*::*****:*** ******:**.*****::: ::* .**: : :.: *****::*******:**:* **:***** :**: * :. . ****:***************:*****:*********.*. *:****:.:*::**************** ****.* *.**:: * *:. * **:**:* .* : *::* *:.: : :** * **:*:* .* . * **:* :*:**.:: ** :*:: ** ***: *** :*:*. *::*** :: :: .* ** : . : ::*.: *** :: *:*:**: :*:. *: . . **** :* ** *: * : **:**:* ::* :*::*****:** *.*.* .: * **::*:****** ********::**.:** :****.:* **:* : *: :*****:*****:*******.*: :. ** ::: :* **: *. *. : . :: :::*.: .****.:* **:*****::.::**:: . . :*:::: **: *** *:: : *:. * . : .** ::: . . . ::.**: .: : :*:*: * * : * ** :*:: *.*******: *:*:*.********.***:********:*::*******::* ** :::*: : *:: ::..* :*.*:**: ::*::**::..* :*:*:**:**:****:*: ::: :.* .:****: * :*.::***::*:::::: **:.*******..**:*:******:. *:*.******:.** **: .** : : .:. ***:** :** *: ** **:********::** * ** .** : :: : **:.*: ** . : ** ** :** **::* ** :* ** :*. *:.**. *: :*.:** :* * :* * : ***** :***** *** ******* *********:* ** ** ****** : *::*:*****::*: *.:** **: *: :.*:*** : :::: **:** *:*: * ** ******:****: ::::*: * **::** : :* *:::* :* *: *: :*.:: : **:*..:* :**:**: * ** **:***.**: *::** ::*: : : ** **:** ::*:**:* **: :* .* * * : .:. :. :*.* :: **: * * ***** **** ****** . *****:******::**::::. * : :: *:. *: :*:::. * ****:::*.:*.** .**.* ****: ::***** *::..********:*****:**:*** **:***** ****:**** **. * ****.:* ::* *** *** ** ***.**:**:*:. *.*.: ** *** ** *. ::: ** **: * .*:.:*: **.** **::***::.:*. *:*:*:****:* **::*: * .. ** :*::.** .::** *****.*** : :::::::*: .:: * ***** * .. **::*: . :**.: *: :.* .:*:*:* :* *:*: *: **:*::* :** :* **:**::*::********: :*:*:.:* *. :. * ::* ..:** ********:*::*** *:: *: : .: *:******* :** *: * . * :**:******* :** *** :* * . ::*:*:****:. *. *:*******.::*:.****:** ****** ***:*::** . :* ***:***:*******..***********: **** ***.** .**:*:**.. ::*::************************ :** * :: ::::*:: *.*.* * * *:.*** *: :* *** ************** :*:::**::*:***:. . . .*:: ** :::::::: :***: :: :**.::*:::**:*** *** * *::***:** ***:****::..** *: ::: * ** *:: **** ** ** ** *::** * ** :*. :** *:*****:****** **::: ***:* :.**:***.:::. .* :*. ::.::*:** ** * . : : *:: .:**: :::: :**: : :* **:*** ** *:* .:.***::.*.:* *.******* ", "identical_positions": 1710, "similar_positions": 1326, "identity": "34.93%" }, { "cls_id": "homologset.agr.MGI:1289280", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BKX7-1", "uniprot_id": "ZN410_MOUSE", "id": "Q8BKX7-1", "name": "Zinc finger protein 410", "aln": "----------------------------------------MLSDELESKPELLVQFVQNTSIPLGQGLVESEAKDITCL-SLLPVTEASECSRLMLPDETPNHANSSKEVPSSAVLRSLQVNVGP----------------DGEETRAQTVQKSPEFLTTPESPSLLQDLQ----------------------------PSDSTSFILLNLTRAG----------LGSSAEHFVFVQDETEDSGAD-------------------FLSAESTDSSIPWFLR---------------------------VQELAHDSLIAATRAQ------------LAKNAKTGSNGENVHLGSGDGQPKDSGP-------------------------------LPQAEKKLKCTVEGCDRTFVWPAHFKYHLKTHRNERSFICPAEG--------------------------------------------------------------------------------------------------------------------------------------------------------------CGKSFYVLQRLKVHMRTHNGEKPFMCHESGCGKQFTTAGNLKNHRRIHTGEKPFLCEAQGCGRSFAEYSSLRKHLVVHSGEKPHQC--QVCGKTFSQSGSRNVHMRKHHLQLG-------------------------------------------------TTGSQEQDQTAEPLMGSSLLEDASVPNKNLVSMNSQSSLGGESLNLSNTNSILG-------------VDDEVLTERASRPLSSVPDVTHHLVTMQSGRQSYEVSVLTAVNPQELLNQGDLTERQT----------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86VK4-1", "uniprot_id": "ZN410_HUMAN", "id": "Q86VK4-1", "name": "Zinc finger protein 410", "aln": "----------------------------------------MLSDELESKPELLVQFVQNTSIPLGQGLVESEAKDITCL-SLLPVTEASECSRLMLPDDTTNHSNSSKEVPSSAVLRSLRVNVGP----------------DGEETRAQTVQKSPEFLSTSESSSLLQDLQ----------------------------PSDSTSFILLNLTRAG----------LGSSAEHLVFVQDEAEDSGND-------------------FLSSESTDSSIPWFLR---------------------------VQELAHDSLIAATRAQ------------LAKNAKTSSNGENVHLGSGDGQSKDSGP-------------------------------LPQVEKKLKCTVEGCDRTFVWPAHFKYHLKTHRNDRSFICPAEG--------------------------------------------------------------------------------------------------------------------------------------------------------------CGKSFYVLQRLKVHMRTHNGEKPFMCHESGCGKQFTTAGNLKNHRRIHTGEKPFLCEAQGCGRSFAEYSSLRKHLVVHSGEKPHQC--QVCGKTFSQSGSRNVHMRKHHLQLG-------------------------------------------------AAGSQEQEQTAEPLMGSSLLEEASVPSKNLVSMNSQPSLGGESLNLPNTNSILG-------------VDDEVLAEGSPRSLSSVPDVTHHLVTMQSGRQSYEVSVLTAVNPQELLNQGDLTERRT----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3ALU5-1", "uniprot_id": "A0A8M3ALU5_DANRE", "id": "A0A8M3ALU5-1", "name": "Zinc finger protein 410", "aln": "----------------------------------------MLSDELDSKPELLVEFVQNACIPLGESLEEAELK--------------PSCVPLELPESALSHAVSP---PLSDLCP--------------------------ERSPVLVQLQSP---AAAQTPTILQELQ----------------------------NNDSTSYILLNLAKG-----------LAASAEPLVFVQDEVDEAQEE-------------------VSVSG--DISTPWYLR---------------------------VQELAHDSLIAATRAQ------------LARDARATANSEHLLSCASDGQKRESSPRV-----------------------------SSRSEKIHRCPYESCCRTFTYPAHLKYHLKTHRNDRTFRCGAEG--------------------------------------------------------------------------------------------------------------------------------------------------------------CGKSFYVLQRLQVHMRTHNGEKPFICSENNCGKKFTTAGNLKNHRRTHTGEKPFLCEVNNCGRSFAEYSSLRKHMLVHSGEKPHVC--SVCGKTFSQSGSRNVHMKKRH------------------------------------------------------SGDDSSTDTGYSNIDNNGREIATCTSEALTQSSLLEEEGGVSLHHSILRTQSF-------------CQDGTCSPAAPTDPLAALAPPHELVSMTTG-HTYSDDVVTLL--------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P41696-1", "uniprot_id": "AZF1_YEAST", "id": "P41696-1", "name": "Transcription factor AZF1", "aln": "MPPPTAQFMGPTQAGQNESQNQSSGEAGEQNQEHGQGPTPILNQSQPASSQPQHQQQRNESISYYTNFNQPRYSTDASINSFLNISDNVPVTSTGGPSSGGAYSNLPRLSTSSTHQPPDLSQIGRGFSIVNNLFPQQQQLQNQHRQQQQQQQQQSHQQPPFKTPSFSTGLTGSSSQYQFLPRNDNTSQPPSKRNSVYLGPNDGPDFEFFSMQQSQQPQFQPSSRRESNSMRPPLLIPAATTKSQSNGTNNSGNMNTNADYESFFNTGTNNSNSNQNPYFLSSRNNSLKFNPEDFDFQFKRRNSFVRGTLDHSSQNAFIPESRLNSLSVNNKANGDPVADNVTNNMKGKSNEVDNDDGNDSSNNNNNNNNNNNNENNNDNNNDNNDNSINSATSTNIPNQEDHSLASTDTTSNSRKDLKEIEQRLRKHLNDEDNYSSAISRPLDKNDVIEGSEGLNKHIDESGMQPNIIKKRKKDDSTVYVKNEMPRTDPPMSKDNSTSAEGAAMANFSGKEPPIPDISSVSDDATNLIGATKVDQLMLIIQARKKGFTEKVNTTQDGDLLFNQTMDILPPKSELVGGVEKPKGTQNTRAVKKHECPYCHRLFSQATHLEVHVRSHIGYKPFVCD--YCGKRFTQGGNLRTHERLHTGEKPYSCDI--CDKKFSRKGNLAAHLVTHQKLKPFVCKLENCNKTFTQLGNMKAHQNRFHKETLNALTAKLAEMNPSENIPLEERQLLEYFASIYKNSNRGIKGRGKGVGTKKSTISSPENHPASTILNPNTNANNAIANDSENNGNPEGNIDSSSNSNPGSHSMISPTQKDMGTLQSQFIQNNFNNSVNSSNPSNQPIINYNYTTLPHSRLGSSSSSNTNNNNSNFSVGAAPGVLMAPTTNNDFSFNLDQSNDNERSQQEQVRFKNINYKS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*.:. :..: : :* .*. .: :.. . *.. :: . . * .. :.. .. ::.:: * .*...: ::.: :. . * . ::: . .: : . . *::* ::. :::::*. :* : :* :. :.: .**: ... .. *. .. : .: .:: :*:.* *:. . * . * : * :*:**:*:* * ***:* ***:** .***:.*.* ******: *: *.:.*:. ..* *::.*. **. * . *.***:* *. :.* .: * : .. . ... . :. . : ... . . . .. * . .: :: . :. .:: . . . * ", "identical_positions": 67, "similar_positions": 167, "identity": "7.3%" }, { "cls_id": "homologset.agr.MGI:1289282", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q969S3-1", "uniprot_id": "ZN622_HUMAN", "id": "Q969S3-1", "name": "Cytoplasmic 60S subunit biogenesis factor ZNF622", "aln": "---MATYTCITCRVAFRDADMQRAHYKTDWHRYNLRRKVASMAPVTAEGFQERVRAQR-AVAE--EESKGSATYCTVCSKKFASFNAYENHLKSRRHVELEKKAVQAVNRKVEMMNEKNLEKGLGVDSVDKDAMNAAIQQAIKAQPSMSPKKAPPAPAKEARNVVAVGTGGRGTHDRDPSEKPPRLQWFEQQAKKLAKQQ----EEDSEEEEEDLDGDDWEDIDSDEELECEDTEAMDDVVEQDAEEEEAEEGPPLGAIPITDCLFCSHHS---SSLMKNVAHMTKDHSFFIPDIEYLSDIKGLIKYLGEKVGVGKICLWCNEKGKSFYSTEAVQ---AHMNDKSHCKLFTDG-DAALEFADFYDFRSSYPDHKEGEDPNK----------------------AEELPSEK-------NLEYDDETMELILPSGARVGHRSLMRYYKQRFGLSRAVAVAKNRKAVGRVLQQYRALGWTGSTGAA----LMR-ERDMQYVQRMKSKWMLKTGMKNNATKQMHFRVQVRF--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q91VY9-1", "uniprot_id": "ZN622_MOUSE", "id": "Q91VY9-1", "name": "Cytoplasmic 60S subunit biogenesis factor ZNF622", "aln": "---MAALTCITCRVAFRDAELQRAHYKTDWHRYNLRRKVAAMAPVTAEGFQERVRAQR-AVAEAAEASKGAATYCTACGKKFATFNAYENHLGSRRHAELERKAVRAASRRVELLNAKNLEKGLGADGVDKDAVNAAIQQAIKAQPSTSPKKAPFVPTDECG---RAAAGARGVPERDPTEKPPRLQWFEQQAKKLAKQQWEDGEEEGEEEEEDDEDEDWEDIDSDDGLECED----PGVEDQDAEDAAAEESPPLGAIPITDCLFCSHHS---SSLVKNVAHMTKVHSFFIPDIEYLSDLKGLIKYLGEKVGVGKICLWCNEKGKSFYSTEAVQ---AHMNDKSHCKLFTDG-DAALEFADFYDFRSSYPDYKEGQDPAE----------------------LEALSTDK-------ILECDDETMELILPSGARVGHRSLMRYYKQRFGLPRAVTVARNQKAVGRVLQQYRALGWMGSTGAA----LMR-ERDMQYVQRMKSKWMLKIGMKNNATKQMHFRAQVRF--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9VX08-1", "uniprot_id": "Q9VX08_DROME", "id": "Q9VX08-1", "name": "C2H2-type domain-containing protein", "aln": "---MSHFTCLNCDARFASADVQRNHYKTDWHRYNLKRRVAQLPPVTAEEFQQRVLSAR-SATDAALEEQNLSVYCHACRRQFASQKAHDNHLNSRKHKELLARFER------EQMTAS--------GGSASTATSVCTRSVVEQRPHPAL---------------AAAAAGKG-----------RLAFAERVVK-----------ANNDEEMVDEDDDDFEDIEEEE-------------VDSDEWDKIPEN-----PLTERDCLFCTHAS---EDLVENLKHMSVAHSFFIPDTEYCTDIEGLLYYLGEKVANYFICLFCNDRGKTFYSLDAVR---KHMIDKGHCQMLHEG-VALAEYAEYYDYSSSYPDNNEGMDID------------------------EEVVPD----------LLDGDEYQLVLPSGAVIGHRSLLRYYKQRLRPERAVVIKKSDRKLHRVLSEYRALGWTQTQQLS----AARKARDIHLMKRVQSKWQMKLGCKAN-KLQKHYRAQVLI--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38344-1", "uniprot_id": "REI1_YEAST", "id": "P38344-1", "name": "Cytoplasmic 60S subunit biogenesis factor REI1", "aln": "MSSSGVYTCNSCVLTFDSSDEQRAHMKSDWHRYNLKRRVAQLPPISFETFDSKVSAAAASTSKSAEKEKPVTKKELKRREKQALLEKKKKLLEIAR-----ANMLENMQKSQEGN------------TPDLSKLSLQENEENKEK-----------------------------------------------------------EEPKKEEP--------EQLTEEEM------------AERVMQEKLRNRV----DIPLEQCLFCEHNKHF-KDVEENLEHMFRTHGFYIPEQKYLVDKIGLVKYMSEKIGLGNICIVCNYQGR---TLTAVR---QHMLAKRHCKIPYESEDERLEISEFYDFTSSYANFNSNTTPD--------------NEDDWEDVGSDEAGSDD---EDLPQEYLYNDGIELHLPTGIKVGHRSLQRYYKQDLKPEVILTEGQ------GTLVAAETRSFLPAFDKK----GVQTQQRVWQTERFDKKRLDKR-SAKFVNNQPHYRDQLLQ--", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q06709-1", "uniprot_id": "REH1_YEAST", "id": "Q06709-1", "name": "Cytoplasmic 60S subunit biogenesis factor REH1", "aln": "-MSSTFFTCNCCVIQFKTSDLQRYHMKTEWHRYNLKRRIANLPPIGAEQFAEKLQISEKEQAENQVDEFGFPVLKPVMNQSNALPQKQKKPIKSKRGRKVGTNLLKRKDRDIAKEKQNRSVSPSGSISSQLSNLTVGTENTNTDY-----------------------------------------------------------GEDTVSEYGFTSDSNYEYATSDEE------------LDIADKPSDKENE----KITITECIYCGKDN---KEVERNVKHMFSEHGLFIPERSYLIDLNGLLEFLIKMIVIDHNCLCCNFHGS---GLESIR---AHMASKRHCRLPYETKEERQLFAPFYDFTYDDHSISKNLQNDRAITSKLSSVYGAKNDEEDGEVDITLVSSENDINANYTTVSIDESGLELTLPTGARLGHRAGQRYYRQNLPSQPNPNESR------RTITAADRRMVSGVTEKQ----YKKGMKKMQQLEKNAINTQIRR-EIKRVNFQTHYRDELLQ--", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q5FVM3-1", "uniprot_id": "RETR1_RAT", "id": "Q5FVM3-1", "name": "Reticulophagy regulator 1", "aln": "--MASPAPEEHATQGCPATEEQEPRPGVPGEEAGPEGAGPQVEEAAGRVAAALTWLLGEPVLWLGWRADELLSWKRPLRSLLAFLGANLLFWFLALTPWRVYHLISVMILGRVIMQIIKDMVLSRARGAQLWRSLSESWEVINSKPDERPR-------------------------------LSHCIAESWMNFSIFLQEMSLFKQQSPGKFCLLVCSVCTFFTILGSYIPGVILSYLLLLFAFLCPLFKCNDIGQKIYSKVKSILLKLDFGIGEYINQKKRERSEADKEKSHKDDSEIDFSALCPKISLTVAAKELSVSDTDVSEVSWTDNGTFNLSEGYTPQTDTSDDLDRPSEEVFSRDLSDFPSLENGAGTNDEDELSLG-----------------LPTELKTKKQQLNSAHRPSKDRQSAAGLSLPLKSDQALHLMSNLAGDVITAAMTAAIKDQLEGARQALAQAAPTPGDDTDTEEGDDFELLDQAELDQIESELGLTQDQGAEAQQSKKSSGFLSNLLGGH", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . :: *. : .. . . . : . * . . : . . ..: . : .: . . . . * .* : : .: . . . : . : *: . . . . * ** . : . : : .: : : : . . : :: ", "identical_positions": 8, "similar_positions": 60, "identity": "1.51%" }, { "cls_id": "homologset.agr.MGI:1289288", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9NWF4-1", "uniprot_id": "S52A1_HUMAN", "id": "Q9NWF4-1", "name": "Solute carrier family 52, riboflavin transporter, member 1", "aln": "--------------------------------------------------------------------------------------------------MAAPTLGRLVLTHLLVALFGMGSWAAVNGIWVELPVVVKDLPEGWSLPSYLS-------VVVALGNLGLLVVTLWRQ-----------------------------------------------------LAPGKG-EQVPIQVVQVLSVVGTALLAPLWHHVAPVAGQLHS----------------------------------------------------------------------VAFLTLALVLAMACCTSNVTFLPFLSHLPPPFLRSFFLGQGLSALLPCVLALVQGVG---------------------------RLECPPAPTNGTSGP-----PLDFPERFPASTFFWALTALLVTS-----------AAAFRGLLLLLPSLPSVTTGGSGPELQLGSPGAEEEEKEEEEALPLQEPPSQAAGTIPGPDPEAHQLFSAHGAFLLGLMAFTSA---------------------------------------------------VTNGVLP---------SVQSFSCLPYGRLAYHLAVVLGSAANPLACFLAMGVLCRSLAGLVGLSLLG----MLFGAYLMALAILS--------------------------------PCPPLVGTTAGVVLVVLSWV-------------------------------LCLCVFS---------------YVKVAASSLLHG--------------GGRPALLAAGVAIQVGSLLGAGAMFPPTSIYHVFQSRKDCVDPCGP---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9HAB3-1", "uniprot_id": "S52A2_HUMAN", "id": "Q9HAB3-1", "name": "Solute carrier family 52, riboflavin transporter, member 2", "aln": "--------------------------------------------------------------------------------------------------MAAPTPARPVLTHLLVALFGMGSWAAVNGIWVELPVVVKELPEGWSLPSYVS-------VLVALGNLGLLVVTLWRR-----------------------------------------------------LAPGKD-EQVPIRVVQVLGMVGTALLASLWHHVAPVAGQLHS----------------------------------------------------------------------VAFLALAFVLALACCASNVTFLPFLSHLPPRFLRSFFLGQGLSALLPCVLALVQGVG---------------------------RLECPPAPINGTPGP-----PLDFLERFPASTFFWALTALLVAS-----------AAAFQGLLLLLPPPPSVPTGELGSGLQVGAPGAEEEVEESS---PLQEPPSQAAGTTPGPDPKAYQLLSARSACLLGLLAATNA---------------------------------------------------LTNGVLP---------AVQSFSCLPYGRLAYHLAVVLGSAANPLACFLAMGVLCRSLAGLGGLSLLG----VFCGGYLMALAVLS--------------------------------PCPPLVGTSAGVVLVVLSWV-------------------------------LCLGVFS---------------YVKVAASSLLHG--------------GGRPALLAAGVAIQVGSLLGAVAMFPPTSIYHVFHSRKDCADPCDS---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B5MEV3-1", "uniprot_id": "S52A2_RAT", "id": "B5MEV3-1", "name": "Solute carrier family 52, riboflavin transporter, member 2", "aln": "--------------------------------------------------------------------------------------------------MAAPPLGRLVLTHLLVALFGMGSWIAVNGIWVELPVVVKELPEGWSLPSYLS-------VLVALGNLGLLLVTLWRR-----------------------------------------------------LAPGKS-ERIPIQVVQGLSIVGTGLLAPLWSNMALVAGQLHS----------------------------------------------------------------------VAFLTLAFVLALSCCASNVTFLPFLSHLPPPFLRSFFLGQGLSALLPCVLALAQGVG---------------------------RLECLHVPANGTTGPPIKVSPINFPERFSAGTFFWVLTALLGTS-----------AAAFQGLLLLLPSPPPEAT--MGTGLRVETPGTEEEEEEEE-ASPLQEPPGQVASIVSSPDPKAHRLFSSRSACLLGLLAITNA---------------------------------------------------LTNGVLP---------AVQSFSCLPYGRLAYHLAVVLGSSANPLACFLAMAVLCRSLAGLYGLCLLG----MFFGTYLMTLAVLS--------------------------------PCPPLVGTSAGVVLVVLSWV-------------------------------LCAGVFS---------------YIKVATSSMLHS--------------GGRPALLAAGVAIQVGSLLGAIAMFPPTSVYPVFRSGEDCVDQCGP---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D8F3-1", "uniprot_id": "S52A2_MOUSE", "id": "Q9D8F3-1", "name": "Solute carrier family 52, riboflavin transporter, member 2", "aln": "--------------------------------------------------------------------------------------------------MAAPPLGRLVLTHLLVALFGMGSWAAVNGIWVELPVVVKELPEGWSLPSYLS-------VLVALGNLGLLLVTLWRR-----------------------------------------------------LARGKG-EQVPIRVVQGLGIVGTGLLASLWNHVAPVAGKPYS----------------------------------------------------------------------VAFLTLAFVLALACCASNVTFLPFLSHLPPPFLRSFFLGQGLSALLPCVLALGQGVG---------------------------RLECLHVPANRTTGPPIEVSPINFPERFSATTFFWVLTALLGTS-----------AAAFQGLLLLLPSPTSEPT--TGTGLRVETPGTEEEEEEEE-ASPLQEPPGQVAGIVSSPDPKAHQLFSSRSACLLGLLAITNA---------------------------------------------------LTNGVLP---------AVQSFSCLPYGRLAYHLAVVLGSCANPLACFLAMAVLCRSLAGLCGLSLLG----MLLGSYLMTLAALS--------------------------------PCPPLVGTSAGVVLVVLSWV-------------------------------LCAGTFS---------------YIKVAISSMLHS--------------GGRPALLAAGVAIQVGSLLGAVAMFPPTSIYRVFRSGKDCVDQCGL---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9V9S9-1", "uniprot_id": "Q9V9S9_DROME", "id": "Q9V9S9-1", "name": "Riboflavin transporter", "aln": "-----------------MSRYHRGRGAGSPTNPAGPVYGVISTLD-----------------DATPSPADFARCSSLEAKKSELSLFLNWGGPQKNMEISSKLRNRSWLVDVLAIFFGIGTWLGVNGTFIQLPLLVDEAPEGWSLPSYLS-------VMVQIGNLGPLLYTAIQK-----------------------------------------------------YSPKKLNDGWTIHGVLLVGAISCLLTAFFYNQTASVAGTDHS----------------------------------------------------------------------LALFLLTCFTALNACTSSVLFMPYMGRFKEQYMVTYFIGEGLSGLLPSVTALIQGIGE--------------------------SGDCVLVNVTESGEE--VYALRKTPPRFDTRVFFLILFALMVLA-----------YVGYALLNSLPLARREYAQVTVSEGNKYVYGEADNQ-------------------------PKAEKLSKGQYTYLLLLIGAISL---------------------------------------------------FSNGMFG---------SIQSYSSAPYGSQAYHLAATLSVIANPVACFMAMFLHFTSLRIITVLSILA----GLLTSYVFTTAALS--------------------------------PLPPLHDQTVGAVLVVTAWT-------------------------------LLVGIVS---------------YTKLGITTVMRA--------------QGGQSLVWVGAITQLGSAIGAVAIFFAINYSDLFQAAESNC--------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0AC58HXG3-1", "uniprot_id": "A0AC58HXG3_DANRE", "id": "A0AC58HXG3-1", "name": "", "aln": "MEDLQDFGSSSASAKTIAAELKDDFYSKLVDDFLGAHYGDLLELDGKNWKNRMLVQIGLLREEQDVSWVDLIQWLQKIIPMFKSADFRSLIERNTTTALSLTGDARENFFESDVNFEFVGPICDSIGIGRRDLLEMSDLSDRAKLTALTNGLVLELTNFISREKLDPVVLVSWIRNFEPLFCSDGKIQRAYKLLRGNLRIFRMQYRNNQRSRKRSRGLLEEFLQSPFDLSPEADADDVEYRRVAMNKAHLKRKRRMYKHTTAMKDEDEHFNISQIDVTVKTHEPMRHEPMQHEPKQHEPKQMPHAMFVKKELGSQTHQSQNQNPEEDTKTDTGDNVTLLDIAVLSWQKMAGIYGGPNEAAKVVSLDLLQNHFNAMLKNDDDLRSLDEKVKASTHPIVPPLDFLRYISQFLFELIDVTEQQMISFEKDIVFTTAEKLGRDKHPRFQTFVNFEESAVTRYINMASEMLCPSDVTNPNYRRLWLAFCLERKIPSSLPIYRSNRVINYFEAAAGLIHHHEEVALFVSDLQLLNNNSSILLDSINADANDKTLQTLVCVVAIIYLKVLGPFWQLLKSDGEYPFFSRYIFCLYDKLLECSLDTSRLLQPENFVNVFLQAPIQEGTFAGVFRFCRDNADNQYGTLLKTCLQKMMKALAAVMEDNLKDFLPGGKHCKDLPGDIAVQMANCTFLQLMGEYPFGHTYPYKKKRPDKAVNQTEGCASKEAQQEPASQKVSDTPTSPAASLSPQKTIQMQQWISKPYSIIEGANLKKMKASRLKQRAQGHIYRKMIIGTISKYGGPCKSKQDVERLLQKLEGASLNHKREVIRSELNYQKSISGSRDKKLSNIGFSLNDMVSTLKDVLPNDKSIVSPSTENVLDHSTDPNSSIASRP", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: * : . . : :*. * . : :.: .: .*.: . .: :*. :: . : : : : * * : :*.: . .: .... : :. : : .:.* .* * * : : : . . : . : : : : . .: : . . ... ..* . :: :: . :* : : :.:. : . . : : *:. .* : : : * : : * .* . : .: : * : .* *: ::: : * . .:.. :.: . . . : : :. ", "identical_positions": 23, "similar_positions": 126, "identity": "2.6%" }, { "cls_id": "homologset.agr.MGI:1289293", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q642B9-1", "uniprot_id": "ZNF18_RAT", "id": "Q642B9-1", "name": "Zinc finger protein 18", "aln": "MPVNLGQALGLLPFLAKAEDATFSGSDVIQQRELANPETARQLFRQFRYQVMSGPQETLRQLRKLCFQWLRPEVHTKEQILEILMLEQFLTILPGEIQMWVRKQCPGSGEEAVTLVESLKGDPQKLWQWISIQVLGQEIPFEKENSARCRGDKVEPALEAEPTVEVVPQDLPLQNTSSAPGELLSHGVKEESDLEPELALAASQLPARPEERPTRDQEVGTALLPSLQEEQWRHLDSTQKEQYWDLMLETYGKMVSGVAGISNSKPDLTNMAEYGEELVGLHLHSAEKMARAPCKEDRQENDKENLNLENHRDQGCLDVFDQAPGEAPPQTALSDFFGESEPHHFG-GESVPEALENLQGEGTGAHLFPHERGSGKQLGQHIQSSSSGELSALWLEEKREASQKGQARAPMAQKLPTCRECGKTFYRNSQLVFHQRTHTGETYFHCRICKKAFLRSSDFVKHQRTHTGEKPCKCDYCGKGFSDFSGLRHHEKIHTGEKPYKCPICEKSFIQRSNFNRHQRVHTGEKPYKCTHCGKRFSWSSSLDKHQRSHLGKKPCP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q810A1-1", "uniprot_id": "ZNF18_MOUSE", "id": "Q810A1-1", "name": "Zinc finger protein 18", "aln": "MPVDLGQALGPLPFLAKAEDATFSASDATQQRELANPETARQLFRQFRYQVLSGPQETLRQLRKLCFQWLRPEVHTKEQILELLMLEQFLTILPGEIQMWVRKQCPGSGQEAVTLVESLKGEPQKLWHWISTQVLGQEIPFEKENLTHCPGDKLEPALEVEPSLEVAPQDLPLQNSSSATGELLSHGVKEESDMEPELALAASQLPARPEERPVRDQELGTAVLPPLQEEQWRHLDSTQKEQYWDLMLETYGKMVSGVAGISNSKPDLTNLAEYGEELVGLHLHGAEKMARLPCKEDRQENDKENLNLENHRDQGCLDVFCQASGEAPPQTALSDFFGESEPHRFG-GDSVPEALENHQGEGTGAHLFPYERGSGKQPGQHIQSSSLGELTALWLEEKREASQKGQARSPMAQKLPTCRECGKTFYRNSQLVFHQRTHTGETYFHCHICKKAFLRSSDFVKHQRTHTGEKPCKCDYCGKGFSDFSGLRHHEKIHTGEKPYKCPLCEKSFIQRSNFNRHQRVHTGEKPYKCTHCGKQFSWSSSLDKHQRSHLGKMPCP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P17022-1", "uniprot_id": "ZNF18_HUMAN", "id": "P17022-1", "name": "Zinc finger protein 18", "aln": "MPVDLGQALGLLPSLAKAEDSQFSESDAALQEELSSPETARQLFRQFRYQVMSGPHETLKQLRKLCFQWLQPEVHTKEQILEILMLEQFLTILPGEIQMWVRKQCPGSGEEAVTLVESLKGDPQRLWQWISIQVLGQDILSEKMESPSCQVG------EVEPHLEVVPQELGLENSSSGPGELLSHIVKEESDTEAELALAASQ-PARLEERLIRDQDLGASLLPAAPQEQWRQLDSTQKEQYWDLMLETYGKMVSG-AGISHPKSDLTNSIEFGEELAGIYLHVNEKIPRPTCIGDRQENDKENLNLENHRDQELLHASCQASGEVPSQASLRGFFTEDEPGCFGEGENLPEALQNIQDEGTGEQLSPQERISEKQLGQHLPNPHSGEMSTMWLEEKRETSQKGQPRAPMAQKLPTCRECGKTFYRNSQLIFHQRTHTGETYFQCTICKKAFLRSSDFVKHQRTHTGEKPCKCDYCGKGFSDFSGLRHHEKIHTGEKPYKCPICEKSFIQRSNFNRHQRVHTGEKPYKCSHCGKSFSWSSSLDKHQRSHLGKKPFQ", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***:****** ** ******: ** **. *.**:.***************:***:***:**********:***********:**************************:***********:**:**:*** *****:* ** : . * . *.** :**.**:* *:*:**..****** ****** *.******** *** *** ***::*:::**. :****:*********************** ****:.*.**** *:****.*::** **:.* .* ****************** *.. **.**.*.*::* .** *.** ** *:.:****:* *.**** :* * ** * ** ***: .. **::::*******:*****.*:**********************:************:* ********************************************************:**************************:**** ***************** * ", "identical_positions": 420, "similar_positions": 75, "identity": "75.4%" }, { "cls_id": "homologset.agr.MGI:1289294", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A0N6-1", "uniprot_id": "A0A8I6A0N6_RAT", "id": "A0A8I6A0N6-1", "name": "", "aln": "-------MNTEELELLSDSKYRNYVAAIDKALKNFEYSSEWADLISALGKLNKVLQNN-----AKYQVVPKKLTIGKRLAQCLHPALPGGVHRKALETYEIIFKIIGPKRLAKDLFLYSSGLFPLLANAAMSVKPTLLSLYEIYYLPLG-KTLKPGLQGLLTGILPGLE-EGSEYYERTNTLLEKVAAAVEQ-SAFYSALWGSLLTSPAVRLPGITYVLAHLNRKLSMEDQLYIIGSDIELMVEAVSTSVQDSSVLVQRSTLDLILFCFPFHMSQATRPDMIRILSAALHVVLRRDMSLNRRLYAWLLG--FDNNGAIIGPRSTRHSNP--EEHATYYFTTFSKELLVQAMVGILQVNGFGEESTLMQDLKPFRILISLLDKPELGPVILEDVLIEVFRTLYSQCKAELDLQMEPPFSKDRAQLSSKLRENKKTAELIKTANLLFNSFEPYYMWDYIARWFEECCR-------RTLHARLEVGPGDSSDASEFQLTTFCSLVDFLLDIVSLPTRSMRVLCQETYIEIQTEHLPQLLLRMISALTSHLQTLRLSELTDSLRLCSKILSKVQPPLLS-------------------------------------------------------------AGTGGVVQFPSGQNSAVKEWEDKK-VSSVSMENPTEVFEDGENPPSSRSSESGFTEFIQYQAERTDDLDRELN-GQGTATIPIGSTSSETETASTVGSEETVIQPPSTLTQGAAGRTGKAVQK---TAMQCCLEYVQQFLSRLIHLYILHSDSFPQASAADHQSDLSRIQRDTSKWDRDSQGDAKERNIHTPKTSKEY-------LSAFLAACQLFLECSSFPVYIAEGNHTSESHSEKPDTDCEHAHPPQWLQTLMSACSQASDFSVQSVAVSLVMDLVGLTQSVAMVTGEN------------------------------------INSMEPAQPLSPNQGRVAVVIRPPLTQGNLRYIAEKTEFFKHVALTLWDQLGDGTPQHHQKSVELFYQLHNLVPS----SSICEDVVSQQLTHKD------------KKVRMEAHARFAVLWHLTRDLHVNKSS------------------FARSFDRSLFIMLDSLTS-LDGSTSSVGQAWLNQVLQRHDIARVLEPLLLLLLHPKTQRVSVQRVQAERYWSKTSCYPGEENDKHFMQNFTCNNVSQVHLIASKGSREKPLTMDEIENFSLTVN--------------PLSDRLSLLSTSSETIPMVVSDFDLPDQQMEILQSSDSGCSQSSAGDNFSYEVDPENVSAHEDSHLAKASSPDDDVQQVVFDLICKVVSGLEAESASVTSELEIESLPPKSSDFDLGKEATKTE----DQAPQHSQHVLLSDDSPRFLSVSTEEGCECLANGISRNSSSPCISGTAQTLTDSSVSS-ETKSRQR----SHSSIQFSFKEKLSEKISEKETIVKESGKQPGAKPKVKLARKKDEDKKKAASEKLKQTNVFFSDG-----------LDLENWYSCGEGEISEIESDMGSPGSRKSPNFNIHPLYQHVLLYLQLYDSSRTLYAFSAIKSILKSNPVAFVNAISTTSVNNAYTPQLSLLQNLLARHRISVMGKDFYSHIP-VDSNHNFRSSMYIEILISLCLYYMRSHYP------THVKVTTQDLIGNRNMQMMSIEILTLLFTELAKVIESSAKGFPSFISDMLSKCKVQKVILHCLLSSIFSVQKWHSEKTAGKNMVAVEEGFSEDSLINFSEDEFDNGSTLQSQLLRVLQRLIVLEHRVMTIPEES--EAGFDFVVSDLEHVSPHQPMTSLQYLHAQPITCQGMFLCAVIRALHQHCACKMHPQWIGLITSTLPYMGK-VLQRVVVSVTLQLCRNLDNLIQQYKYETGLSDSRPLWVASIIPPDMILTLLEGITAIIHYCLLDPTTQYHQLLVNVDQKHLVEARSGILSILHMIMSSVTLLWSILHQADASEK------------------MGLAASASVTTINLGATKNLRQQILELLGPISMNHGVHFMAAIAFVWNGRRQNKTPS--------RTKVIPAASEEQLLLVELVRSISVMRAETVIQTVKEVLKQPPAIAKDK--KHLSLEVCMLQFFYAYIQRIPVPNLVDSWASLLVLLKDSIQLSLPAPGQFLILGVLNEFIMKNP--SLENKKDQRDLQDVTHKIVDAIGAIAGSSLEQTTWLRRNLEVKPSPKIMVDGTNLESDVEDMLSPAMETSNITPSVYSVHALTLLSEVLAHLLDMVFYSDEKERVIPLLVNIMHYVVPYLRNHSAHNAPSYRACVQLLSSLSGYQYTRRAWKKEAFDLFMDPSFFQMDAS------CVSHWRAIMDNLMTHDKTTFRDLMTRVAVAQSSSLNLFANRDVELEQRAMLLKRLAFAIFSSEIDQYQKYLPDIQERLVESLRLPQVP-TLHSQVFLFFRVLLLRMSPQHLTSLWPTMITELVQVFLLMEQELTADEDISRTSGPSAAGLETTYTGGNGFSTSYNSQR----WLNLYLSACKFLDLALALPSENLPQFQMYRWAFIPEASDDSGLEVRRQGIHQREFKPYVVRLAKLLRKRAK-----------------KNPEEDGSARTLGWEPGHLLLTLCTMRNMEQLLPFFNVLSQVFNSKVTSRCGGHSGSPILYSNSFPSKDMKLENHKAFSSKARQKIEEMIEKDFLEGVIKT----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BL99-1", "uniprot_id": "DOP1A_MOUSE", "id": "Q8BL99-1", "name": "Protein DOP1A", "aln": "-------MNTEELELLSDSKYRNYVAAIDKALKNFEYSSEWADLISALGKLNKVLQNN-----AKYQVVPKKLTIGKRLAQCLHPALPGGVHRKALETYEIIFKIIGPKRLAKDLFLYSSGLFPLLANAAMSVKPALLGLYEMYYLPLG-KTLKPGLQGLLTGILPGLE-EGSEYYERTNTLLEKVAAAVEQ-SAFYSALWGSLLTSPAVRLPGITYVLAHLNRKLSMEDQLYIIGSDIELMVEAVSTSVQDSSVLVQRSTLDLILFCFPFHMSQATRPDMIRILSAALHVVLRRDMSLNRRLYAWLLG--FDNNGAIIGPRSTRHSNP--EEHATYYFTTFSKELLVQAMVGILQVNGFGEESTLMQDLKPFRILISLLDKPELGPVILEDVLIEVFRTLYSQCKAELDLQMEPPFSKDHAQLSSKLRENKKTAELIKTANLLFNSFEPYYMWDYIARWFEECCRQSFFLSRRTLHARLQVGPGDSSDSSELQLTNFCLLVDFLLDIVSL----------ETYIEIQTEHLPQLLLRMISALTSHLQTLRLSELTDSLRLCSKILSKVQPPLLS-------------------------------------------------------------AGNGGVVQFPSGQNSTVKEWEDKKQVSSVSMENPAEVFEDGENPPSSRSSESGFTEFIQYQADRPDDLDRELN-GQGAATIPIGSTSSETETASTVGSEETVIQPPSTFTQGAAGRSGKAVQK---TAMQCCLEYVQQFLSRLINLYIIHSDSFPQALAADHQGDFSRIQRETSKWDRDSQGDAKERNIHTPKTSKEY-------LSAFLAACQLFLECSSFPVYIAEGNHTSESHSEKPDTDCEHAHPPQWLRTLMSACSQARDFRVQSAAVSLVMDLVGLTQSVAMVTGEN------------------------------------INSMEPAQPLSPNQGRVAVVIRPPLTQGNLKYIAEKTEFFKHVALTLWDQLGDGTPQHHQKSVELFYQLHNLVPS----SSICEDVVSQQLTHKD------------KKIRMEAHAKFAVLWHLTRDLHINKSS------------------FARSFDRSLFIMLDSLTS-LDGSTSSVGQAWLNQVLQRHDIARVLEPLLLLLLHPKTQRVSVQRVQAERYWSKTSCYPGEENDKHFMQNFTCNNVSQVHLIASKGNGEKPLTMDEMENFSLTVN--------------PLSDRLSLLSTSSETIPMVVSDFDLPDQQMEILQSSDSGCSQSSAGDNFSYEVDPENANAHEDSHMAKASSPDDDVQQVVFDLICKVVSGLEAESESVTSELEIESLQTKSSDLDPGKEATKIE----DQAPQHSQHVLLSDDSPRFLSVSTEEGCECLANGISRNSSSPCISGTAQTLNDSSVPS-ETKSRQR----SHSSIQFSFKEKLSEKVSEKETIVKESGKQPGAKPKVKLARKKDEDKKKAASEKLKQANVFFSEG-----------LDLENWYSCGEGEISEIESDMGSPGSRKSPNFNIHPLYQHVLLYLQLYDSSRTLYAFSAIKSILKTNPIAFVNAISTTSVNNAYTPQLSLLQNLLARHRISVMGKDFYSHIP-VDSNHNFRSSMYIEILISLCLYYMRSHYP------THVKVTTQDLIGNRNMQMMSIEILTLLFTELAKVIESSAKGFPSFISDMLSKCKVQKVILHCLLSSIFSVQKWHSEKTAGKSMVAVEEGFSEDSLINFSEDELDNGSTLQSQLLRVLQRLIVLEHHVMTIPEEN--EAGFDFVVSDLEHISPHQPMTSLQYLHAQPITCQGMFLCAVIRALHQHCACKMHPQWIGLITSTLPYMGK-VLQRVVVSVTLQLCRNLDNLIQQYKYETGLSDSRPLWVASIIPPDMILTLLEGITAIIHYCLLDPTTQYHQLLVNVDQKHLVEARSGILSILHMIMSSVTLLWSILHQADASEK------------------MAVAASASVTTINLGATK--------------------------------------------------VIPAASEEQLLLVELVRSISVMRAETVIQTVKEVLKQPPAIAKDK--VRK-LCFCRKFSFRTGADRIPVPNIVDSWTSLLVLLKDSIQLSLPAPGQFLILGVLNEFIMKNP--SLENKKDQRDLQDVTHKIVDAIGAIAGSSLEQTTWLRRNLEVKPSPKIMVDGTNLESDVEDMLSPAMETSNITPSVYSVHALTLLSEVLAHLLDMVFYSDEKERVIPLLVNIMHYVVPYLRNHSAHNAPSYRACVQLLSSLSGYQYTRRAWKKEAFDLFMDPSFFQMDAS------CVSHWRAIMDNLMTHDKTTFRDLMTRVAVAQSSSLNLFANRDVELEQRAMLLKRLAFAVLSSESDQYQKYLPDIQERLVESLRLPQV------------------------------------QVFLLMEQELTADEDISRTSGPSAAGLETTYTGGNGFSTSYNSQR----WLNLYLSACKFLDLALALPSENLPQFQMYRWAFIPEASDDSGLEVRRQGIHQREFKPYVVRLAKLLRKRAKDEEDFKILEGLEMAKHQKNPEEDCSGRTLGWEPGHLLLTLCTMRNMEQLLPFFNVLSQVFNSKVTSRCGGHSGSPVLYPNSFPNKDMKLENHKAFSSKARQKIEEMIEKDFLEGVIKT----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5JWR5-1", "uniprot_id": "DOP1A_HUMAN", "id": "Q5JWR5-1", "name": "Protein DOP1A", "aln": "-------MNTEELELLSDSKYRNYVAAIDKALKNFEYSSEWADLISALGKLNKVLQNN-----AKYQVVPKKLTIGKRLAQCLHPALPGGVHRKALETYEIIFKIIGPKRLAKDLFLYSSGLFPLLANAAMSVKPTLLSLYEIYYLPLG-KTLKPGLQGLLTGILPGLE-EGSEYYERTNMLLEKVAAAVDQ-SAFYSALWGSLLTSPAVRLPGITYVLAHLNRKLSMEDQLYIIGSDIELMVEAVSTSVQDSSVLVQRSTLDLILFCFPFHMSQATRPDMIRILSAALHVVLRRDMSLNRRLYAWLLG--FDNNGAIIGPRSTRHSNP--EEHATYYFTTFSKELLVQAMVGILQVNGFGEENTLMQDLKPFRILISLLDKPELGPVILEDVLIEVFRTLYSQCKAELDLQTEPPFSKDHAQLSSKLRENKKTAELIKTANLLFNSFEPYYMWDYVARWFEECCR-------RTLHVRLQIGPGDSNDSSELQLTNFCLLVDFLLDIVSLPTRSMRVLCQETYIEIQTEHLPQLLLRMISALTSHLQTLHLSELTDSLRLCSKILSKVQPPLLS-------------------------------------------------------------ASTGGVLQFPSGQNNSVKEWEDKK-VSSVSHENPTEVFEDGENPPSSRSSESGFTEFIQYQADRTDDIDRELSEGQGAAAIPIGSTSSETETASTVGSEETIIQTPSVVTQGTATRSRKTAQK---TAMQCCLEYVQQFLTRLINLYIIQNNSFSQSLATEHQGDLGREQGETSKWDRNSQGDVKEKNISKQKTSKEY-------LSAFLAACQLFLECSSFPVYIAEGNHTSELRSEKLETDCEHVQPPQWLQTLMNACSQASDFSVQSVAISLVMDLVGLTQSVAMVTGEN------------------------------------INSVEPAQPLSPNQGRVAVVIRPPLTQGNLRYIAEKTEFFKHVALTLWDQLGDGTPQHHQKSVELFYQLHNLVPS----SSICEDVISQQLTHKD------------KKIRMEAHAKFAVLWHLTRDLHINKSSS-----------------FVRSFDRSLFIMLDSLNS-LDGSTSSVGQAWLNQVLQRHDIARVLEPLLLLLLHPKTQRVSVQRVQAERYWNKSPCYPGEESDKHFMQNFACSNVSQVQLITSKGNGEKPLTMDEIENFSLTVN--------------PLSDRLSLLSTSSETIPMVVSDFDLPDQQIEILQSSDSGCSQSSAGDNLSYEVDPETVNAQEDSQMPKESSPDDDVQQVVFDLICKVVSGLEVESASVTSQLEIEAMPPKCSDIDPDEETIKIE----DDSIQQSQNALLSNESSQFLSVSAEGGHECVANGISRNSSSPCISGTTHTLHDSSVASIETKSRQR----SHSSIQFSFKEKLSEKVSEKETIVKESGKQPGAKPKVKLARKKDDDKKKSSNEKLKQTSVFFSDG-----------LDLENWYSCGEGDISEIESDMGSPGSRKSPNFNIHPLYQHVLLYLQLYDSSRTLYAFSAIKAILKTNPIAFVNAISTTSVNNAYTPQLSLLQNLLARHRISVMGKDFYSHIP-VDSNHNFRSSMYIEILISLCLYYMRSHYP------THVKVTAQDLIGNRNMQMMSIEILTLLFTELAKVIESSAKGFPSFISDMLSKCKVQKVILHCLLSSIFSAQKWHSEKMAGKNLVAVEEGFSEDSLINFSEDEFDNGSTLQSQLLKVLQRLIVLEHRVMTIPEEN--ETGFDFVVSDLEHISPHQPMTSLQYLHAQPITCQGMFLCAVIRALHQHCACKMHPQWIGLITSTLPYMGK-VLQRVVVSVTLQLCRNLDNLIQQYKYETGLSDSRPLWMASIIPPDMILTLLEGITAIIHYCLLDPTTQYHQLLVSVDQKHLFEARSGILSILHMIMSSVTLLWSILHQADSSEK------------------MTIAASASLTTINLGATKNLRQQILELLGPISMNHGVHFMAAIAFVWNERRQNKTTT--------RTKVIPAASEEQLLLVELVRSISVMRAETVIQTVKEVLKQPPAIAKDK--KHLSLEVCMLQFFYAYIQRIPVPNLVDSWASLLILLKDSIQLSLPAPGQFLILGVLNEFIMKNP--SLENKKDQRDLQDVTHKIVDAIGAIAGSSLEQTTWLRRNLEVKPSPKIMVDGTNLESDVEDMLSPAMETANITPSVYSVHALTLLSEVLAHLLDMVFYSDEKERVIPLLVNIMHYVVPYLRNHSAHNAPSYRACVQLLSSLSGYQYTRRAWKKEAFDLFMDPSFFQMDAS------CVNHWRAIMDNLMTHDKTTFRDLMTRVAVAQSSSLNLFANRDVELEQRAMLLKRLAFAIFSSEIDQYQKYLPDIQERLVESLRLPQVP-TLHSQVFLFFRVLLLRMSPQHLTSLWPTMITELVQVFLLMEQELTADEDISRTSGPSVAGLETTYTGGNGFSTSYNSQR----WLNLYLSACKFLDLALALPSENLPQFQMYRWAFIPEASDDSGLEVRRQGIHQREFKPYVVRLAKLLRKRAK-----------------KNPEEDNSGRTLGWEPGHLLLTICTVRSMEQLLPFFNVLSQVFNSKVTSRCGGHSGSPILYSNAFPNKDMKLENHKPCSSKARQKIEEMVEKDFLEGMIKT----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1ZBE8-1", "uniprot_id": "DOP1_DROME", "id": "A1ZBE8-1", "name": "Protein DOP1 homolog", "aln": "--MESADALVEEQKLMAEAKYRTYMTNIDKALRNFEYSSEWADLISALGKLSKAISSN-----TQYQVIPRRLKIAKRLAQCMHPALPSGVHLKALETYSVIFSKTGPERLAT-EFIYSAGLFPLLGYAAMNVRPALLAIYETYFVPLG-DKLRPALSGFLNGVLPGYD-CGLDHFERISALLKQVCNAVNP-MHFYTVLWESVANNAAIRLPAITYLLEHFNKRLDMQEQIYIMGHNREIMMSALCVCLNDSLILVQRNTLEFLLLGFPMHTVLLSEDDLVKLVTNGLNTILRRDMSLNRRLFSWLLGSEVAKNSPTYDTLSLDTSNAPLEEEPEPYFVKHSRHILIKALITTLRLS----LECAPMDLKPYRIMLSLLDKAEIGSAVLDYVLHDIIRAMYISS---------------------------GNAEALKSANLLFATFDPAYIWSYMTNMFEKACQQANSMQEKSQAGETSGKYACDVGSGDPCVLEICVLTEFLLETVSL----------EMYTETTRVYLPKVFLAITQLLSLHMDHISSNEITASLKLCMKIVSRVQPMITSPIKLNKLIEQSGGSSSDEKITMNSASDAGKTEAGAQGNSLEKSKSDSRLNQFAENTLHSADPNDEELIHRSASNQSVGRQSPNKKKAKSISRLSELDKDISASDTGQQSSSDLDTPRSIKKLKAKAKVPFIRSPKKQRPKDMVLIQSNTSAEVSDGPSAEEPKSAPPDQTPQFQLDEESRATQQRGFSILEKCIRQYEIFFEVYLSRKLLHIESEPKECSVKVQLQRTTSTIHTSNLFMAEQVLDHECPVRESQIERLFNLLRVDIVPRSKQLQRLLNRSLPLPASASELSSDSEAQEEKQQSLLIDGQTQRSVQQLAELQLSPSLRGAVKLAATLLVEMSTFPNCNKHVVLDKNEPELPNWLKVLCLVACFAQSDKELQVASITTLFDLISLLRSQIEHTTSPGVTFVVMLPLLKFGHVSYMEQHTRVFQLVSSILWDYLGTAG-IDPAQIAALLHQLHSCLESGLVETVIGNRMQSQHLLQMQSQSRSDLGKAAIRNFQMERLAEAQLLCPTESTERLRESQARSFKKFELLWHLGRDKQTARGFEKTLLKVLDTLALPHYMSERTFVTNWLQASLLRGDLARLTKPLYKILLSASSKRVGIVHMQQLYRESETEVTPAFERDVYAISSEQGNVKYHHMETSSGNKKKSPIRNFPKKIFGVTLSGGKANKVSNFVSDKSTVATCSEATQDMNTIGLIINPLENANDFDDETDLEEPRIEIPHKETPLEQKLASAMDESEQPSQEQPANQPDNSLQYDQDITDHSDSSDFESDSELRETSIEKEDSITVSSSAGVSDDVKRFVGDCESVTDALTQHEKIKSRKTYRLTREKTPGENSLNSLEQKDHDSISELQADALPADEYFREDKKLGKRKKVLTSGEKKRLSCISKTSTDSNISGSHVEQPEQEEETEPGTESTINVEDKRRNLSLETSKLQPDMQKTLEKGKQNVEILRQNNAAAAAAAAAAAEEQISVRSSMKSTVSLTDAAHLYHNHLLIYLAIYDTRQTLYALQTLRNIICCDKRTFLCLSITTSFSSAS------LKQLLVRHRKSISGKGFDGSVGNSEYAQGYRGCMQLELLVTLCLFYARGYFQKESLDAQRQSPTLQDIVNNRRIQLESIELLTLICSELIEIVKGMGRGLANYIADLLARAKLQKVMLHCLNSSVCSYGLKGNTNSG--------SYAEQVLSFNDPQDDQLHADCFQLQLLRLLLAVIRLEHEVHQLRQDTPPAAGEDSAGNASPTRLAEGATANVKYLPNCLISQQPMFLAAVLGALQQERLRHLHRNWTDLVTSSLNCFSFGSLTNIVISVVHQLCSNLDRISKMGLPQQ-----------RHFPPDYVVSQLEALTILCHYCLLDNTQQTALSHLFNQAYPQTSSSAQSSSTGQLLNSIVHSFLSASESSTSAPAPRNPQLQAARNAVLSHLPRIMSSVAAIWDSELGQLRPVRQQLLEFLSPVSLHHGSNFLAAVAVTWQQRGIATNMNGLSIAEQFQRNSVLQACPAQLSLVSLVSSIRVMPMDSFVMTLHHVVRSPPPIHRPP--AQLSIEVSALELFYFYMKSAPAPQLADAWSSLLALIRDGLNLTP--PAQFALLMLLNEFVQRCPQMPFQDKKEVRELHDVTSRLVDSLSSVAGSCLEQTTWLRRNLAVKEDT--------------DGLAKDNSVGGGGLQQYSLQAQSVLAAILSNLLDVAYGSQEKDKVVNIVTPLLYNITPYLKNHTARNVPFFYACSALLASLSGYQYTRKAWRKDMLDLLLDNAFFQMHLS------CLPFWRMIMDSLMTYDNTTFRELMTRVSLSQAGSLNIFTSRDQEYEQRAMLLKRLAFVIYCSEFDQHNKYMPDIQEQLANSLRLVPMGPSVQAAVFLCFRVLLLRMSPDHVTSLWPIIIAEMVQVFLQMEQELKSESEERNQQLRLPSGIDVSWSAASGASNGYNSQTPMQHWRSVQLEACKLLELGCVLPATKLPHFQMYRWAFVGTEFDVHEEEVCLPNGSLENLATLPSALYVPHVRRVAR--------------LMDMKYTSQSPILQRPSNRHLMLHFQQLQSLQELYAFFTTLGISCP-----------------------QPRNFADTENDVANCLKEIEEVLANDFLEKLPSITTPR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q03921-1", "uniprot_id": "DOP1_YEAST", "id": "Q03921-1", "name": "Protein DOP1", "aln": "MSLPLKPLTIDSNNKQLDSKQKKFRANVERALERFDSVTEWADYIASLGTLLKALQSWSPKFQNVRYYVPSPYQVSRRLTSSLSPALPAGVHQKTLEVYTYIFEHIGLETLATECNIWIPGILPLMTYASMSVRSHLIELYDNYILLLPQTTLRLLIRPLISSLLPGIDDESNDFLPLTLKLIETLQENLDDDSLFWQTLFLVMTANKGRRLGGLTWLTRKFPSLNAVPHLVNKIKMEAEENPSETET--NDSHLDRKKRKEEAFKVLLPAAKDLVTPEPGLLIRCLVGCLEDENDILIKRSVLDLLLQR-LRLDSPVLN----------------VLITSEDKKLLIMSCC----------RTTLSKDMSLNRRIWNWLLGPTAGGMLNNNGGNSMEYTTSVKS-------------------------------ANEESNVYFTKYGLSALLEGLSDLLSE----------------------------------------------------------------EESVLTAFRISMAVMDRWEIGSLVIPELFIPLLYSSEKFKQNEQIMKT---------------------------------------------------------------ARTFFDNTETNIIWGKLFQELEDIKNLKILDFVLTNFN--------------------------------------------------------------------------------------------IGNDEEIIVRHLPLILLTLLALP-------------------------SNDKDFDNIYKLQKFSLYN-----------KLLNYIPERALLPLSHSKLKHDDEVSCEELLAKIRGFYTN------------------VSNPSSILEKEN------------------------------------------------------------------IAERLPPFTTEDLTFLIADLIQKKLLSS-LWDLENINE------SSKLFIAIFEKIPE-------SEELKGRSHISWSD-----------KKITQSIFEAIPRLCESNNDAKSEEIVG-----------------IVEIFGNYLYSRMEFIES-------------------MKLLKVVMMAVWKSLKDPRHQILGVKNLKTLNRFIPSKFIESALVYTFVEEEDISERLSVLDLLWTQLDSDSNLIRRPLELI------------------------LGELFDDQNPFYLTVSKWILS-------------ILNSGSASRLFYILTDNILKVNRLEKERLDERDDLDMLTYEFQMLAYV---LKTNNGRTRKVFSTELTSIKSSTIWKNEDVSTYK-------------SLLLVTLMRFLNIKSNTHAKSIR--------------SALILLDILLDG----------------TEQNFKDIVIFLLQMSSKYIAEEGIEPELIAVSLLDIVSKVLRLSHDNG-----------------------------------------------------------------IKLDIFDDN--------------AAHLKYIDFLVTSVSN----------------------------------MKSPLIVTAYVKLLSESIVYFENSIFR----------------------MILPLSASLVQCVQRLFLLEKREGGYYQPIALLLGGLEELLEISHGYLVTEEREGYFSGSNLKGDFIQSVVSNVFSSDSSNEESKIQGERDVILQSFRQVISCCLDIWYWAHNISCKSNDDSSLDATNHNSYKFKFRSKK----------------------------------------------------------------------------------------------------LLETLFLLEPLELLENLISIRSDNTTVTLVHVLDGNKPAITIPHLLYGVIIRYN---------------------------------------------------------------------------------------------------------------RTASVKFSNRDGSRSSTTKLTKGEPSMLKRLSGE------SIIAFLFNYVDSVENSAMEEFYGDFLLFFREVATNYNLYSDVSLSILKLVALISGKVS-----KTQFGEQKRVRREISDVFFKYLPNAFINFTNLYR-----------------------------------GHPDSFKDLEFVVWRVQYIVNDQIGGDKFN--TTLATIVNQCLTPYIKPKSEKTIPGY--VLELAAVVSHLGSKVKSWRLLIAELFQNDKKLSVIGSDQTWEKIIYEWSIYPENKSKILNDLLLEIGSKRSSVTPTLITFNLGSDSEVEYKCQNLLKISYLLMVSPNDAYLLHFSSLISCIFHYLVSKDIK--LKGSCWILLRVLLLRFSESHFNDYWSMISYCLQTNLQEFYESLQIQSEVDPQT---------------------------------ILQVCKTLDLLLLLNMEGFTSTNEWIFVIDTINCVYKTNSFVALVDEIAEFKDYEITKTDDLELPTT-----------------------------LKDGLPLLRGIHKIERHTQLRSFFQNLS----------------------------YLHYEKVYGLGSVDLYGCGEDLKKDILS---------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. : ::* :.: : :::**..*: :**** *::**.* *.:.. :* :.:**:..: ****.*** *:**.* **. * : **. :: .*::**: *:*.*:. *: :*: * : * .*: : ::..:*** : . :. *:: : :: *: .*: : . . ** .:*:: :: : . : : : * . . :** : :: . : : . :* : : : ..*: ::* : ** . :.. . :.. .:.:*: : *:. * : . * . * : : .: : .. : :*: * .: : . :: :.: *. . : : .: : *: .* . : ..: : : : ... . : : : : ..:. . . : : :: : :: : . . . : : : . : . :* :: . .* *: : . . . ::: . . * :. .: :: . : :: *** . *: :.. : . : : .: . ::. . * : .: .. * . * :: : : : .: * . : :.: .:: : . . .. . : . .. : : : . . :.: : :. . . : : . .. .: . * .: :: :. . :. * .* ..:. : *. . :.: : * . . . . . . . : : : . . : . : * ::* :: *: . :::* ::: .. : : .:. : : ::: * . *: :*. : : * : . : . . * .. . . : .: ::: : : : . : .. :. * . . ** : : **: . .. : ::: . : . *: . : : .: : *.: : . : . . : : : .:* :::: . : * :: *.: : : * .: * : ..: : * * * *.: .: : ::: .:: : : . : :.**:: :: :. * : * : :* . ::*: :*: : :.: * : * :. . : : :: :: : . :.: . * * * :. * :::: : * * : ::..: . : . * : : : :.* :.: *..** *:* * :. : : :.: .. :: . . *: : :. :* .** *. : . : * : :*:*. ", "identical_positions": 143, "similar_positions": 533, "identity": "5.22%" }, { "cls_id": "homologset.agr.MGI:1289298", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AXN6-1", "uniprot_id": "SKAP_RAT", "id": "Q6AXN6-1", "name": "Small kinetochore-associated protein", "aln": "MATHKAEAQETDFRTTGPPTDLEQCPFPPSSRKFPFESVAADSTEGWAVAAEHHLKRSGEDGGWEQPASGVEPSRPTTMAS-SKTVCDAQPHSMPSCGLSADTQTRATSK--LPVKSKDAEMLRHLHTGGLEPDVTKVTKPRRENGQGKAAETASRRNIRSSYKPLSKQKPEEDLKDKNELLEAVNKQLHQKLTETQGELKDLTQKVELLEKFQDNCLAILESKGLNS--GQETQESKQEPSTDPTDSMLLLETLKDELKLFNETAKKQMEELQALKVKLKLKEKERIQFLEQQTLGKDEASDFTIILEEMEQLLEM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D9Z1-1", "uniprot_id": "SKAP_MOUSE", "id": "Q9D9Z1-1", "name": "Small kinetochore-associated protein", "aln": "MAAPEAEAQETAFRTTGPPTDSEPRPFPPSSRKFPFESAAADSNEDWAVAAEHYLKGSGENGGWEQPAPGVQPSHPATMAS-AKTVCDAQPHSMPSCGLPADTQTRATSK--LPVKSKEADLLRHLHPGGPEPDVTKVTKSRRENGQVKAAETASRRNLRNSYKPFNKQKPEEELKDKNELLEAVNKQLHQKLTETQGELKDLTQKVELLEKFQDNCLALLESKGLNP--GQETLASKQEPTTDHTDSMLLLETLKDELKVFNETAKKQMEELQALKVKLKLKEEESVQFLEQQTLCKDEASDFTIILEEMEQLLEM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y448-1", "uniprot_id": "SKAP_HUMAN", "id": "Q9Y448-1", "name": "Small kinetochore-associated protein", "aln": "MAAPEAPPLDRVFRTTWLSTECDSHPLPPSYRKFLFETQAADLAGGTTVAAGNLLNESEKDCGQDRRAPGVQPCRLVTMTSVVKTVYSLQPPSALSGGQPADTQTRATSKSLLPVRSKEVDVSKQLHSGGPENDVTKITKLRRENGQMKATDTATRRNVRKGYKPLSKQKSEEELKDKNQLLEAVNKQLHQKLTETQGELKDLTQKVELLEKFRDNCLAILESKGLDPALGSETLASRQESTTDHMDSMLLLETLQEELKLFNETAKKQMEELQALKVKLEMKE-ERVRFLEQQTLCNNQVNDLTTALKEMEQLLEM", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**: :* . : **** .*: : *:*** *** **: *** . :*** : *: * :: * :: *.**:*.: .**:* *** . ** * * * .********** ***:**:.:: ::**.** * ****:** ****** **::**:***:*..***:.***.**:*****:*********************************:*****:******:. *.** *:**.:** *********::***:*******************::** * ::******* :::..*:* *:********", "identical_positions": 198, "similar_positions": 67, "identity": "62.46%" }, { "cls_id": "homologset.agr.MGI:1289301", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q499N6-1", "uniprot_id": "UBXN1_RAT", "id": "Q499N6-1", "name": "UBX domain-containing protein 1", "aln": "MAELTALESLIEMGFPRGRAEKALALTGNQGIEAAMDWLMEHEDDPD-------------------VDEPLETPLSHILG---------------------REPTPSEQVGPEG---SGSAAGESKPVLTEEERQEQTKRMLELVAQKQREREEREEREALEREKQRRRQGQELSAARQKLQEDEIRRAAEERRREKAEELAARQRVREKIERDKAERAQKYGGTVGSR--SSPPATDPGPVPSSPRQEPPTKREYDQCRIQVRLPDGTSLTQTFRAREQLAAVRLYVELHRGEEPGQDQDPVQLLSGFPRRAFSEADMERPLQELGLVPSAVLIVAKKCPS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q922Y1-1", "uniprot_id": "UBXN1_MOUSE", "id": "Q922Y1-1", "name": "UBX domain-containing protein 1", "aln": "MAELTALESLIEMGFPRGRAEKALALTGNQGIEAAMDWLMEHEDDPD-------------------VDEPLETPLSHVLG---------------------REPTPSEQVGPEG---SGSAAGESRPILTEEERQEQTKRMLELVAQKQREREEREEREALEREKQRRRQGQELSVARQKLQEDEMRRAAEERRREKAEELAARQRVREKIERDKAERAKKYGGSVGSR--SSPPATDPGPVPSSPSQEPPTKREYDQCRIQVRLPDGTSLTQTFRAREQLAAVRLYVELHRGEEPGQDQDPVQLLSGFPRRAFSEADMERPLQELGLVPSAVLIVAKKCPS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q04323-1", "uniprot_id": "UBXN1_HUMAN", "id": "Q04323-1", "name": "UBX domain-containing protein 1", "aln": "MAELTALESLIEMGFPRGRAEKALALTGNQGIEAAMDWLMEHEDDPD-------------------VDEPLETPLGHILG---------------------REPTSSEQGGLEG---SGSAAGEGKPALSEEERQEQTKRMLELVAQKQREREEREEREALERERQRRRQGQELSAARQRLQEDEMRRAAEERRREKAEELAARQRVREKIERDKAERAKKYGGSVGSQ--PPPVAPEPGPVPSSPSQEPPTKREYDQCRIQVRLPDGTSLTQTFRAREQLAAVRLYVELHRGEELGGGQDPVQLLSGFPRRAFSEADMERPLQELGLVPSAVLIVAKKCPS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NXA9-1", "uniprot_id": "UBXN1_DANRE", "id": "Q6NXA9-1", "name": "UBX domain-containing protein 1", "aln": "MADCTTLDSLLEMGFGRNRAEKAVAHTGNQGIERAMDWLMEHENDPD-------------------IDEPYVPPAGNTLGP-------------------AEEQSQSPTEIPESI--EDTEEGNARQPMTEEERKEQVKRLEDLMKARQEERRERERQEGIEREKQRRKQGQELLQVRQKLQEDEMKKLADQRRKEKMEDRLAKQRVKDKIARDREERAQKFGGGSSSTGLSSPPAEAPALSPPENQGAPPAKKDYDDCRIQVRLLDGTTLSTVFKAQEPLAAVRVYVQMNG----ANGQD-FNLITPYPRRVYTDLDMEKPLRELGLVPSAVLVVTKK---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VSC5-1", "uniprot_id": "Q9VSC5_DROME", "id": "Q9VSC5-1", "name": "UBX domain-containing protein 1", "aln": "---MSEVQTLMDMGFPRERVEYALEVTSNKGVEPAMEWLLAHVDDPIPSRQGAGESPGSTAQPAAAVDSSAAAASSSTSGAGETSAPVAKSLKCDECGKVLRDHTEVEYHAAKTGHTKFSESEEEKKALTEEEKKAQLALIEEKLKQKRIEREEREKIEALQREKNRIKSGKDMTEAKRRMEELEMKKIVEQRKREKDEEKAARDRVKAQIEADKAARKAREQKELGNAEPAPSVSSTTVSSPPAGVKSPP--RDYTETRIQVRLQDGSTLQETFNVKEQLSAVRVFIQMKTG-----IESPFSLMTTFPRKLFAEDDYEKPLEVLGLVPSAVITMTKTPA-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :::*::*** * *.* *: *.*:*:* **:**: * :** :*.. .. . * .: : : . : : : ::***:: * : : : :: **.***. *.::**::* :.*::: .:::::* *::: .::*::** *: *::**: :* *: * : .. ... : . *. ** ::* : ****** **::* .*..:* *:***:::::: :. ..*:: :**: ::: * *:**. ********: ::*. ", "identical_positions": 82, "similar_positions": 111, "identity": "23.98%" }, { "cls_id": "homologset.agr.MGI:1289302", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4ADF2-1", "uniprot_id": "D4ADF2_RAT", "id": "D4ADF2-1", "name": "", "aln": "MAPGRPSSRLRTGGFAAR--GEGTPQVRFGNQNGKRRTWRPNHQQAFLGSVREGQGFAFRRKLKIQQNYKKLLWKVKKAPASQGSQFEDHYPEHLKHLYLAEEERLRKQ-QRKVDLALSEGQLDQPLPEEE---------GNTEQAVS---EEQSSVFQPQPEE--PSTVNSVTFPKKKRKKTSNQKAQEEYERVQAKRAAKKFEFEMRKQEREEAQRLYKKKKMEAFKILSKKTKKGQPNLNLQMEYLLQKIQENS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R2N0-1", "uniprot_id": "TAP26_MOUSE", "id": "Q8R2N0-1", "name": "Thyroid transcription factor 1-associated protein 26", "aln": "MAPSRPSSKWRTGGFAAR--GEGISQVRFGNQNGKRRTWRPNPQQAFRGSVRKGQGFAFRRKLKIQQNYKKLLWKVKEAPASQESQFTDRYPEHLKHLYLAEEERLRKQ-QRKAGLALSEEQVDRPLPEEE---------GSTEQTSS---EEPPGGHQPQPEE--LNTGSSVTFPKNKKKKTSNQKAQEEYERVQAKRAAKKFEFEMRKQEREEAQRLYKKKKMEAFKILSKKTKKGQPNLNLQMEYLLQKIQENS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P031-1", "uniprot_id": "TAP26_HUMAN", "id": "Q9P031-1", "name": "Thyroid transcription factor 1-associated protein 26", "aln": "MAPVRRSAKWRPGGIEAR--GEGVSTVGYRNKNVRQKTWRPNHPQAFVGSVREGQGFAFRRKLKIQQSYKKLLRKEKKAQTSLESQFTDRYPDNLKHLYLAEEERHRKQ-ARKVDHPLS-EQVHQPLLEEQ---------CSIDEPLF---EDQCSFDQPQPEEQCIKTVNSFTIPKKNKKKTSNQKAQEEYEQIQAKRAAKKQEFERRKQEREEAQRQYKKKKMEVFKILNKKTKKGQPNLNVQMEYLLQKIQEKC-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5RGP9-1", "uniprot_id": "TAP26_DANRE", "id": "Q5RGP9-1", "name": "Thyroid transcription factor 1-associated protein 26 homolog", "aln": "MAPFKQNAKNK-GPIRGKQFNNKFQRGGLSHNAKRKRKWVPE-DKVFDGSLKEGQGFAFKRKEKVKHEYNKLLRKERKRKQESKVQLQEEYPEHLKHLYLAERERLDEEEQEKKKKRCKGRAVEEDIEEDDDKLNKDLGSSSSEKNITNTSTDQTIAPASSNEPAQPESSHKTTFFQRKQNISSYQKTKQEYERIKEERARKREEILKDKAQREEALKKYKEKKIATYQLLKRKTKKGQPNLNLQMELLLQKIQAQRK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** : .:: : * : .: .: :: :::.* *: :.* **:::******:** *:::.*:*** * :: . *: :.**::********.** :: .* . :.. : *:: . :: : .. * .: . *: :.::: :* **:::***::: :** *: *: * :**** : **:**: .:::*.:**********:*** ****** : ", "identical_positions": 79, "similar_positions": 84, "identity": "30.62%" }, { "cls_id": "homologset.agr.MGI:1289308", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q66HA4-1", "uniprot_id": "TAXB1_RAT", "id": "Q66HA4-1", "name": "Tax1-binding protein 1 homolog", "aln": "----------MTSFQEVPLQTSNFAHVIFQNVAKSYLPNAHLECHYTLTPYIHPHSKDWVGIFKVGWSTARDYYTFLWSPMPEQYVEGSTVNCVLAFQGYYLPNDDGEFYQFCYVTHKGEIRGASTPFQFRAASP-VEELLTMEDEGNSDMLVVTTKAGLLELKIEKTLKEKEELLKLVSVLEKETAQLREQVGRMERELSHEKSRCEQLQAEQKGLLEVSQSLRVENEEFMKRYSDATSKAHQLEEDIVSVTHKAVEKETELDSLKDKLRKAQQEKEQLECQLKTEKDEKELYKVHLKNTEIENTKLVSEIQTLKNVDGNKESMITHFKEEIGKLQSCLADKENLHRALLLTTSNKEDTLLLKEQLRKAEEQVQATRQELIFLAKELSDAVNVRDKTMADLHTARLENERVKKQLADTLAELQLHAVKTDQEKTDT----------------LEHELRREVEDLKLRLQMAADHYKEKFKECQRLQKQINKLSDQSASSNGVFTKRMGSQQKVNDASINTDPAAS--ASAVDVKPAASCAAETDFDMSAKDHVCEVTKEMAEKVEKYNKCKQLLQDEKAKCNK-YADELAQMELKWKEQVRIAENVKLELAELEDSYSLQLAEKDKEINCLASFLENLSREKELTKS--------LEDQKGRKMEGQSPQQVSRCLNTCSEQSGLLPTLPAAQPVLQYGNPYTAHETRDGADGAFYPDEIQR-PPVRGPSW--EDNVVCSQPARNLSRPDGLEDPEDSR---EDENVPIPPDPANQHLRGHGAGFCFDSSFDVHKKCPLCELMFPPNYDQIKFEEHVESHWKVCPMCSEQFPPDYDQQGFERHVQTHFDQNVLNFD---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UKC1-1", "uniprot_id": "TAXB1_MOUSE", "id": "Q3UKC1-1", "name": "Tax1-binding protein 1 homolog", "aln": "----------MTSFQEVQLQTSNFAHVIFQNVAKSYLPNAHLECHYTLTPYIHPHSKDWVGIFKVGWSTARDYYTFLWSPMPEHYVEGSTVNCVLAFQGYYLPNDDGEFYQFCYVTHKGEIRGASTPFQFRAASP-VEELLTMEDEGNSDMLVVTTKAGLLELKIEKTLKEKEELLKLIAVLEKETAQLREQVGRMERELSQEKGRCEQLQAEQKGLLEVSQSLRVENEEFMKRYSDATAKVQQLEEDIVSVTHKAIEKETDLDSLKDKLRKAQHEREQLECQLQTEKDEKELYKVHLKNTEIENTKLVSEIQTLKNLDGNKESMITHFKEEISKLQSCLADKENLYRALLLTTSNKEDTLFLKEQLRKAEEQVQATRQELIFLTKELSDAVNVRDKTMADLHTARLENERVKKQLADTLAELQLHAVKKDQEKTDT----------------LEHELRREVEDLKLRLQMAADHYREKFKECQRLQKQINKLSDQAASTNSVFTKKMGSQQKVNDASINTDPAASTSASAVDVKPAASCA-ETGFDMSTKDHVCEMTKEIAEKIEKYNKCKQLLQDEKTKCNK-YAEELAKMELKWKEQVKIAENVKLELAEVEDNYKVQLAEKEKEINGLASYLENLSREKELTKS--------LEDQKGRKLEGQSPQQVSRCLNTCSEQNGLLPPLSSAQPVLQYGNPYSAQETRDGADGAFYPDEIQR-PPVRVPSW--EDNVVCSQPARNLSRPDGLEDPEDSR---EDENVPIPPDPANQHLRSHGAGFCFDSSFDVHKKCPLCELMFPPNYDQTKFEEHVESHWKVCPMCSEQFPPDYDQQGFERHVQTHFDQNVLNFD---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86VP1-1", "uniprot_id": "TAXB1_HUMAN", "id": "Q86VP1-1", "name": "Tax1-binding protein 1", "aln": "----------MTSFQEVPLQTSNFAHVIFQNVAKSYLPNAHLECHYTLTPYIHPHPKDWVGIFKVGWSTARDYYTFLWSPMPEHYVEGSTVNCVLAFQGYYLPNDDGEFYQFCYVTHKGEIRGASTPFQFRASSP-VEELLTMEDEGNSDMLVVTTKAGLLELKIEKTMKEKEELLKLIAVLEKETAQLREQVGRMERELNHEKERCDQLQAEQKGLTEVTQSLKMENEEFKKRFSDATSKAHQLEEDIVSVTHKAIEKETELDSLKDKLKKAQHEREQLECQLKTEKDEKELYKVHLKNTEIENTKLMSEVQTLKNLDGNKESVITHFKEEIGRLQLCLAEKENLQRTFLLTTSSKEDTCFLKEQLRKAEEQVQATRQEVVFLAKELSDAVNVRDRTMADLHTARLENEKVKKQLADAVAELKLNAMKKDQDKTDT----------------LEHELRREVEDLKLRLQMAADHYKEKFKECQRLQKQINKLSDQSANNNNVFTKKTGNQQKVNDASVNTDPATS--ASTVDVKPSPSAA-EADFDIVTKGQVCEMTKEIADKTEKYNKCKQLLQDEKAKCNK-YADELAKMELKWKEQVKIAENVKLELAEVQDNY------------------------KELKRS--------LENPAERKMEGQNSQ-SPQCFKTCSEQNGYVLTLSNAQPVLQYGNPYASQETRDGADGAFYPDEIQR-PPVRVPSWGLEDNVVCSQPARNFSRPDGLEDSEDSK---EDENVPTAPDPPSQHLRGHGTGFCFDSSFDVHKKCPLCELMFPPNYDQSKFEEHVESHWKVCPMCSEQFPPDYDQQVFERHVQTHFDQNVLNFD---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LWB0-1", "uniprot_id": "TXB1A_DANRE", "id": "Q1LWB0-1", "name": "Tax1-binding protein 1 homolog A", "aln": "MSSSCNVGASAGGGGSVVMETSNFAHVIFQNVGKSFLPQAALECHYTLTPFITPHPKDWVGIFKVGWSSARDYYTFLWSPMPENYTEGSTVHRTIIFQGYYVPRSDGEFYQFCYVTHTGEIRGASTPFQFRPATPTGEELLTVEDDGNSDILVR----------VEEVQQECKELQKALRLLTQERDQLQEKQ-----------------RQQNQELQK---SLIEEKE-------EAQSRVRQLEQDLLKITQKAVLKETELDCLRDKLQKVISERDSLQTQLKNERDERELYKSHVRSAELENTKLSAELQMLKAVELNREVTIAQYQEELHRLR---TERDTHP-----------AETGLKEQLRQAEEQLQATRQQAAMLGSELRDASGGRDRTMTELYRVRQEAEELRAHLAEAQEECRHAQDQLDRMKNQTSQEMGRAGGGVGVASELEAELQKEVEELKLRLNMAAEHYKEKYRECQRLRRQVTKLTQQ---------------QETQQGDANRNDAS-TETTLELHTPDAETPSESYP-----AEIKTVARDVEKSRDEEGNEQEEEDEEEEECSLSVEAELACMEEKWREQCTINENLKLLLANEEKRFKTQVAEKDREVSALRESLVVVTKEKERLEKQYMR----EGTTRSRRLEVREPVVLRYPLP-YPQDPPPLPLVPQQPAELQFGNPYLEQETRDGADGALSPEQTCRPPPLAPPPWG--GPVVCSQPSRSLSPPDGLENPTEERPTGGDGEAPAVCEHQSLESNESHTSFCFDTRPDVHKQCPLCEVIFPPHFEQSSFERHVESHWRVCPVCSEQFPLDCQQQLYEKHVHTHFDGNVLNFDNFD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6P132-1", "uniprot_id": "TXB1B_DANRE", "id": "Q6P132-1", "name": "Tax1-binding protein 1 homolog B", "aln": "-----MALFLEGTAASSAMETSNFAHVIFQNVGKSYLPHGALECHYTLTQFIKPHPKDWVGIFKVGWSTARDYYTFLWSPLPDNYTEGTAINRSVVFQGYYVPNDDGEFYQFCYVTHKGEIRGASTPFQFRANSPTEEELLTMEDEGGSDILVVTTKASYLEQKMEQIQQEKKELLENLDLLQKERDELIDEKNRLEKEYEQERESSAQLRKDVQELQLSAQSLQEEREEVKRRMEESTARLLQLEEDLIGVTQKGLQKETELDCLKDRVKKLNLEKEALEGQLKNEKDEKELYKIHLKNRELENTKLSAELQMLKSVDVNKENTIAQLKDELARVKSCLAEKEKQHRQLLANSSPSGESKALREQLRQKEEQLQATQQQANMLKAELRDSSNARDRSMAELYRIRVEAETLKKGQADARAECSRLEQQLEEMKSSTQQEAQCKESDVLAV----AELQREVEDLRLRLQMAAEHYKDKYKECQKLQKQVVKFNEQ---------------QGVKRSPGSDAAAGPLSASPEASAPGSPSTSDAVLDAIIHGRLKSSSKELDKN-DKYRKCKQMLNEERERCSM-ITDELTKMEVKLREQMKTNESLRMQLAAEEDRYKSQVAEKGRELKELKDSLFVLTKEKEKLEGQLQKSVNREEEQKDSNLDVQS-VFLQYPMP-YAQDDPSPLLVPQRPTDLLFGNPYSSTDSRDGADGEFSDDQMPRLPPVGPPSWD--SNVVCIQPARNLSRPDGLEEPEEPQSTQNDDEPAAPEPAEFL--NDGQMPFCFEP-TGEQKRCPLCEVIFPPHYDQSKFEEHVESHWKICPMCSEQFPLDCDQQLFEKHVLTHFDSNVLNF----", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . ::************.**:**:. ******** :* **.************:***********:*::*.**:::: : *****:*..************.*************. :* *****:**:*.**:** :*: :* :** : : :* :* :* :: : : : * ** *.* :: :: ***:*:: :*:*.: ***:**.*:*:::* *:: *: **:.*:**:**** *::. *:***** :*:* ** :: *:* *:: ::*: ::: ::::. *:****: ***:***:*: :* ** *: . **::*::*: * * * :: *:: * : :. *..* **::***:*:***:***:**::*::***:*::*: *:.:* * .: . . * :: * . . :: .: :::: .. :: : :: ::*. .*. **: ** * :** *.::: ** :. : ** . .:: :. : .:: :. . * :**** ::****** : :: * **: *.* . *** **:*.:* *****:. : : * : . . ***:. . :*:*****::***:::* .**.******::**:****** * :** :*:** **** ***** ", "identical_positions": 289, "similar_positions": 216, "identity": "33.6%" }, { "cls_id": "homologset.agr.MGI:1289318", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5BK07-1", "uniprot_id": "CCD43_RAT", "id": "Q5BK07-1", "name": "Coiled-coil domain-containing protein 43", "aln": "MAAPSEVAAAVLGEGDGGG--FGSWLDGRLEALGVDQAVYRAYILGVLQEEE-EEEKLDALQGILSAFLEEDSLLDICKEIVERWSET----RDVTTKVKKEDEVQAITTLIEKQ--AQIVVKPRVVSEEEKQRKAALLAQYADVTDEE-----DEADEKADPGASTANIGSDKSLFRNTNVEDVLNARKLERDSLRDESQRKKEQDKLQREKDKLAKQERKEKEKKRTQRGERKR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CR29-1", "uniprot_id": "CCD43_MOUSE", "id": "Q9CR29-1", "name": "Coiled-coil domain-containing protein 43", "aln": "MAAPSEVAAAVLGEGDGGA--FGSWLDGRLEALGVDRAVYAAYILGVLQEEE-EEEKLDALQGILSAFLEEESLLDICKEIVERWSET----RDVTTKVKKEDEVQAIATLIEKQ--AQIVVKPRVVSEEEKQRKAALLAQYADVTDEE-----DEADKKDDAGASTANVSSDRTLFRNTNVEDVLNARKLERDSLRDESQRKKEQDKLQREKDKLAKQERKEKEKKRTQKGERKR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96MW1-1", "uniprot_id": "CCD43_HUMAN", "id": "Q96MW1-1", "name": "Coiled-coil domain-containing protein 43", "aln": "MAAPSEVAAIAPGEGDGGGGGFGSWLDGRLEALGVDRAVYGAYILGILQEEE-EEEKLDALQGILSAFLEEDSLLNICKEIVERWSET----QNVVTKVKKEDEVQAIATLIEKQ--AQIVVKPRMVSEEEKQRKAALLAQYADVTDEE-----DEADEKDDSGATTMNIGSDKLLFRNTNVEDVLNARKLERDSLRDESQRKKEQDKLQRERDKLAKQERKEKEKKRTQRGERKR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PFL6-1", "uniprot_id": "CCD43_DANRE", "id": "Q6PFL6-1", "name": "Coiled-coil domain-containing protein 43", "aln": "MAAPEQIA----GE-------FENWLNERLDSLEVDREVYGAYILGVLQEEESDEEQKDALQGILSAFLEEETLEEVCQEILKQWTECC--SRSGAKSNQADAEVQAIASLIEKQ--AQIVVKQKEVSEDAKKRKEAVLAQYANVTDDE-----DEAEEEEQ---VPVGIPSDKSLFKNTNVEDVLNRRKLQRDQAKEDAQKKKEQDKMQREKDKLSKQERKDKEKKRTQKGERKR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9PD03-1", "uniprot_id": "M9PD03_DROME", "id": "M9PD03-1", "name": "Coiled-coil domain-containing protein 43", "aln": "MSATDDFQ---------------SWLNEQLRKLNTDENVFGSYIIGILEGDETTDEKTEALEGILSETGSAN-IDELVATILQKWLQSHPSADDPPKKGLDIDVNAQLAKLLEQQKLQPAVNKEREYTEEERRIKQQILAQYSQYLMTMPIFLQTAVANEDDENSEAESEDDSGTLTKNTNKSDVQALAKEKREQARMDSAAKKQKDKEDREKQKQLREEKK--EKRKTVKGERRR", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:*..:. .**: :* * .*. *: :**:*:*: :* :*: :**:**** . : : :: *:::* : . .. ::.*:*:* * * : :*: :: * :****:: . :: : . . .. * :*** .** * :*:. : :: **::** :**::* ::*:* **::* :***:*", "identical_positions": 57, "similar_positions": 73, "identity": "24.15%" }, { "cls_id": "homologset.agr.MGI:1289321", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LPD6-1", "uniprot_id": "A0ABK0LPD6_RAT", "id": "A0ABK0LPD6-1", "name": "Large ribosomal subunit protein mL48", "aln": "EHQLEFPQRIPEVSARGHDGAGGAAAAASAQRPLPDRCSSNPLTKRAERKGQPRSPLGPCRAEQRGEAEGRVTPPTGSRRRRLPAESPSTQPGPRPRRDAGRCRRQPAVRSGFASLAPFLPSERGAETELSGLLPCRGERGRSGFDWRLEKTGGGGTEFRVLGLWTNTVSKQGFSLQRFRILGENPIYSAGGIVR-TSRHYKTKPTHGIGRYRHLVKVLEPKKKKAKVELRAINVGTDYEYGVLNIHLTAYDMTLAESYARYVHRLCNQLSIKVEESYAMPTKTMEVMRLPDQGNKMVLDSVLTTHERVVQISGLSATFAEIFLEILQINLPEGVRLSVREHTEEDFKGRFKARPELEELLAKLN-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8JZS9-1", "uniprot_id": "RM48_MOUSE", "id": "Q8JZS9-1", "name": "Large ribosomal subunit protein mL48", "aln": "---------------------------------------------------------------------------------------------------------------------------------MSGTLG------------------------KVLGVWTNTVSKQGFSLLRFRSLGENPIFSAGGILW-TSRHYKTKPTHGIGRYRHLVKVQEPKKKKAKVELRAINVGTDYEYGVLNIHLTAYDMSLAESYAQYVHRLCNRLSIKVEESYAMPTKTMEVMRLPDQGNKMVLDSVLTTHERVVQISGLSATFAEIFLEVLQSNLPEGVRLSVREHTEEDFKGRFKARPELEELLAKLN-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96GC5-1", "uniprot_id": "RM48_HUMAN", "id": "Q96GC5-1", "name": "Large ribosomal subunit protein mL48", "aln": "---------------------------------------------------------------------------------------------------------------------------------MSGTLE------------------------KVLCLRNNTIFKQAFSLLRFRTSGEKPIYSVGGILLSISRPYKTKPTHGIGKYKHLIKAEEPKKKKGKVEVRAINLGTDYEYGVLNIHLTAYDMTLAESYAQYVHNLCNSLSIKVEESYAMPTKTIEVLQLQDQGSKMLLDSVLTTHERVVQISGLSATFAEIFLEIIQSSLPEGVRLSVKEHTEEDFKGRFKARPELEELLAKLK-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VQ35-1", "uniprot_id": "Q9VQ35_DROME", "id": "Q9VQ35-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLRRILPSVRLALQVPKATTTA------------VRSTSGSVYEPDYLESLKPKFP---------------QYESLNVQIKGYDYPQLESYQRFLHGLAEYLDLDVSDCYALPPQKTTVQRLRPNSTVIESEYKLTTYERNLQLNNVDAPVYPQFLRLAQAALPEGVSLQVQEYTDDCEERRYVPDKELLDLKDELERMGGPTTTRKK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: :. *: :. :. .:.* * . :: :** :* **:::..** . *** :::* *.: *.:.*.:.**:*.:. * :* :.. : : ***:** :*:..:.*.. **.: * ***** *.*:*:*:: : *: . ** :* :*: ", "identical_positions": 46, "similar_positions": 67, "identity": "12.23%" }, { "cls_id": "homologset.agr.MGI:1289325", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CPV2-1", "uniprot_id": "APC16_MOUSE", "id": "Q9CPV2-1", "name": "Anaphase-promoting complex subunit 16", "aln": "-------------------MAASSSSSSAGGVSGSSVTGSGFSVSDLAPPRKALFTYPKGAGEMLEDGSERFLCESVFSYQVASTLKQVKHDQQVARMEKLAGLVEELEADEWRFKPIEQLLGFTPSSG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96DE5-1", "uniprot_id": "APC16_HUMAN", "id": "Q96DE5-1", "name": "Anaphase-promoting complex subunit 16", "aln": "-------------------MAASSSSSSAGGVSGSSVTGSGFSVSDLAPPRKALFTYPKGAGEMLEDGSERFLCESVFSYQVASTLKQVKHDQQVARMEKLAGLVEELEADEWRFKPIEQLLGFTPSSG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6AKF1-1", "uniprot_id": "A0A8I6AKF1_RAT", "id": "A0A8I6AKF1-1", "name": "Anaphase-promoting complex subunit 16", "aln": "MSARSSLSYTNEERLLLEGMAASSSSSSAGGVSGSSVPGSGFSVSDLAPPRKALFTYPKGAGEILEDGSERFLCESVFSYQVASTLKQVKHDQQVARMEKLAGLVEELEADEWRFKPIEQLLGFTPSSG", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ******************.*************************:*****************************************************************", "identical_positions": 108, "similar_positions": 2, "identity": "83.72%" }, { "cls_id": "homologset.agr.MGI:1289326", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6R518-1", "uniprot_id": "GPN3_RAT", "id": "Q6R518-1", "name": "GPN-loop GTPase 3", "aln": "MPRYAQLVMGPAGSGKSTYCSTMVQHCEALNRSVQVVNLDPAAEHFNYPVMADIRELIEVDDVMEDDSLRFGPNGGLVFCMEYFANNFDWLEN---------CLGHVEDDYILFDCPGQIELYTHLPVMKQLVQQL-EQWEFRVCGVFLVDSQFMVESFKFISGILAALSAMISLEIPQVNIMTKMDLLSKKA-KKEIEKFLDPDMYSLLEDSTGDLRS-QKFKKLTKPVCGLVDDYSMVRFLPYDQSDEESMNIVLQHIDFAIQYGEDLEFKEPKEHEEE-SSSMFDEYFQERQNE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D3W4-1", "uniprot_id": "GPN3_MOUSE", "id": "Q9D3W4-1", "name": "GPN-loop GTPase 3", "aln": "MPRYAQLVMGPAGSGKSTYCSTMVQHCEALNRSVQVVNLDPAAEHFNYPVMADIRELIEVDDVMEDESLRFGPNGGLVFCMEYFANNFDWLEN---------CLGHVEDDYILFDCPGQIELYTHLPVMKQLVQQL-EQWEFRVCGVFLVDSQFMVESFKFISGILAALSAMVSLEIPQVNIMTKMDLLSKKA-KKEIEKFLDPDMYSLIDDSTGDLRS-QKFKKLTKAVCGLVDDYSMVRFLPYDQSDEESMNIVLQHIDFAIQYGEDLEFKEPREHEEE-SSSMFDEYFQERQNE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UHW5-1", "uniprot_id": "GPN3_HUMAN", "id": "Q9UHW5-1", "name": "GPN-loop GTPase 3", "aln": "MPRYAQLVMGPAGSGKSTYCATMVQHCEALNRSVQVVNLDPAAEHFNYSVMADIRELIEVDDVMEDDSLRFGPNGGLVFCMEYFANNFDWLEN---------CLGHVEDDYILFDCPGQIELYTHLPVMKQLVQQL-EQWEFRVCGVFLVDSQFMVESFKFISGILAALSAMISLEIPQVNIMTKMDLLSKKA-KKEIEKFLDPDMYSLLEDSTSDLRS-KKFKKLTKAICGLIDDYSMVRFLPYDQSDEESMNIVLQHIDFAIQYGEDLEFKEPKEREDE-SSSMFDEYFQECQDE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6ZM63-1", "uniprot_id": "GPN3_DANRE", "id": "Q6ZM63-1", "name": "GPN-loop GTPase 3", "aln": "MPRYAQLVMGPAGSGKSTYCATMLEHCQALNRSVQVVNLDPAAEHFEYPVIADIRELIQVDDVMEDDSLRFGPNGGLIFCMEYFSNNFDWLEE---------SLGHVEDDYILFDCPGQIELYTHLPVMKQLVEQL-QQWEFRVCGVFLVDSQFMVETFKFISGVMAALSAMVMLEIPQVNIMTKMDLLSPKA-KKEIEKYLDPDMYSMMEDNSVALRS-KKFSKLTKAICGLIDDYSMVRFLPFDRTDEEGINIVLQHIDFSIQYGEDLEVKEPKEVDEEPSNSNFDAFFQDTADS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VI70-1", "uniprot_id": "Q9VI70_DROME", "id": "Q9VI70-1", "name": "GPN-loop GTPase 3", "aln": "-MRFAQIIVGPAGSGKSTYCSLMQQYAMDCKRNVQVVNLDPAAEHFTYNPLTDIRDLIHLDDAMEDEELHYGPNGGLIFCLEFLIENQEWLKEQLCGGENELMVGEPDDDYILFDMPGQIELFTHLKMGRQLVELL-ESWNFRTCVVFCLDSQFMVDGAKFISGTMAALSVMANMEQPHINVLTKVDLLSSDA-RKQLEMYLEPDAHSLMGELTIGTGFGEKYAKLTQAIGALIEDFSLVRFFPLDSQDEESVGDLLLQIDSILQYGEDADVN-VKDFDEP----------EEGDQD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06543-1", "uniprot_id": "GPN3_YEAST", "id": "Q06543-1", "name": "GPN-loop GTPase 3", "aln": "MSRVGVMVLGPAGAGKSTFCNSIISHMQTVGRRAHIVNLDPAAEATKYEFTIDIRDLISLDDVMEEMDL--GPNGALIYCFEYLLKNLDWLDE---------EIGDFNDEYLIFDCPGQIELYTHIPVLPNIVRHLTQQLNFNLCATYLLEAPFVIDSSKFFSGALSAMSAMILLELPHINVLSKLDLIKGDINKKKLKRFLNPDAMLLMETEGMNQASNPKFLRLNQCIANLVDDFGMVQFLPLESNNPDSIETILSYVDDITQWAEGQEQKEPNDQIDV----------EE----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . :::****:****:* : .: * .::******** * ***:** :**.**: .* ****.*::*:*:: :* :**.: :*. :*:*::** ******:**: : ::*. * :. :*. * .: ::: *::: **:** ::*:*.* :* *::*:::*:**:. . :*::: :*:** :: *: :*.: : *::*:.:*:*:* : : :.: :* :* *:.*. : : .: : :: ", "identical_positions": 86, "similar_positions": 103, "identity": "28.96%" }, { "cls_id": "homologset.agr.MGI:1289332", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5PPK9-1", "uniprot_id": "EIPR1_RAT", "id": "Q5PPK9-1", "name": "EARP and GARP complex-interacting protein 1", "aln": "MEDDAPVIYGLEFQARALTPQTAETDAIRFLVGTQSLKYDNQIHIIDFDDENNIINKNVLLHQAGEIWHISASPADKGVLATCYNKTSDSRVQACAAVWRMPKELESGSHESPEDPASTAQTLELLCHLDNGAQGN-VACVVWEPMGDGKKVISLADSHILLWDLQPSSSQAVLASSAALEGRGQLK----FTSGRWSPHHNCTQVATASDTTLRGWDTR-SMSQIYCIENAHGQLVRDLDFNPNKQYYLASCGDDCKVKFWDTRNVTEPVKTLEEHSHWVWSVRYNHSHDQLVLTGSSDSRVILSNMVSISSE-PFGHLVDDDDVSDPEEHHTE-KSKEPLQDNVIATYEEHEDSVYAVDWASADPWLFASLSYDGRLVINRVPRALKYHILL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K0G5-1", "uniprot_id": "EIPR1_MOUSE", "id": "Q8K0G5-1", "name": "EARP and GARP complex-interacting protein 1", "aln": "MEDDAPVIYGLEFQARALTPQTAETDAIRFLVGTQSLKYDNQIHIIDFDDENNIINKNVLLHQAGEIWHISASPADKGVLATCYNKTTDSRVQACAAVWRMPKELESGSHESPDDPASTAQTLELLCHLDNSAQGN-VACVVWEPMGDGKKVISLADSHILLWDLQPSSSQAVLASSATLEGRGQLK----FTAGRWSPHHNCTQVATASDTTLRGWDTR-SMSQIYCIENAHGQLVRDLDFNPNKQYYLASCGDDCKVKFWDTRNVTEPVKTLEEHSHWVWSVRYNHSHDQLVLTGSSDSRVILSNMVSISSE-PFGHLVDDGDISDPEEHHAE-KSKEPLQDNVIATYEEHEDSVYAVDWASADPWLFASLSYDGRLVINRVPRALKYHILL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q53HC9-1", "uniprot_id": "EIPR1_HUMAN", "id": "Q53HC9-1", "name": "EARP and GARP complex-interacting protein 1", "aln": "MEDDAPVIYGLEFQARALTPQTAETDAIRFLVGTQSLKYDNQIHIIDFDDENNIINKNVLLHQAGEIWHISASPADRGVLTTCYNRTSDSKVLTCAAVWRMPKELESGSHESPDDSSSTAQTLELLCHLDNTAHGN-MACVVWEPMGDGKKIISLADNHILLWDLQESSSQAVLASSASLEGKGQLK----FTSGRWSPHHNCTQVATANDTTLRGWDTR-SMSQIYCIENAHGQLVRDLDFNPNKQYYLASCGDDCKVKFWDTRNVTEPVKTLEEHSHWVWNVRYNHSHDQLVLTGSSDSRVILSNMVSISSE-PFGHLVDDDDISDQEDHRSEEKSKEPLQDNVIATYEEHEDSVYAVDWSSADPWLFASLSYDGRLVINRVPRALKYHILL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5XJP1-1", "uniprot_id": "EIPR1_DANRE", "id": "Q5XJP1-1", "name": "EARP-interacting protein homolog", "aln": "MEDDAPVIYGLEFQARALTAQTAETDAIRFLVGTQSLKFDNQIHIIDFDDENNMINKSVLLHDAGEIWHISGSPADKAVLTTCYNKTSESRVLTCAAVWRMPPEWESGNHESPDDSSNNPQTLELLCHLDNSAHGS-MACVLWEPMGDGKRVISLAENHVLLWDLQESSAKATISSSATLEGKGQLK----FTAGKWSPHHNCTQLATANDTAIRGWDLR-SMSQIYCIENAHGQLVRDLDFNPNKQYYLASCGDDCKVKFWDVRHISEPVKCLEEHSHWVWSVRYNHSHDQLLLTASSDSRVILSNMVSISSE-PFGHLVDDDDLSDPEENQQEDKGKEPLQDSIISTYEEHEDSVYAVEWSAADPWLFASLSYDGRLVINRVPRALKYRILL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VTY5-1", "uniprot_id": "Q9VTY5_DROME", "id": "Q9VTY5-1", "name": "EIPR1-like beta-propeller domain-containing protein", "aln": "MDENS-LIYGLELQARALTPQYGESNDVCFFIATNSLKPTNQVHLIQYEEEQGSVQSKVFEHALGEVWKLNSCPRNPRLLASVYNVQKGAQVLTKAALFTLPENLNP----DPEQLKSEYLPWEQVEVLDTEALGERVKTIEFHPNQD--TLACVVDNKVAVMQRAESSTRVVAEVPASGSSSGSAKHTQHFTSGKWSHHHQGHQFLTLQDGNLSAYDVRDTQHCAWSINDAHGQMVRDLDCNPNKQCHLVTGGDDGYLRIWDCRMPKAPVFERSDHSHWVWCVRFNTFHDQLILSSSSDCKVLLTCAGSVSSETQVQAGLDESNFSGADAEERH----KLLPDGLLQTFDQHEDSVYCAEWSNVDPWIFASLSYDGRVIISKVPKQYKYQIIF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:::: :*****:******.* .*:: : *::.*:*** **:*:*::::*:. ::..*: * **:*::...* : :*:: ** . ::* : **:: :* : :. .*:: . . * : **. * *. : : :.* * : .:.:.:: : : **::.. .*: .. *. * **:*:** **: *. * .* : .:* * : :.*::****:***** ***** :*.: *** :::** * . ** .:****** **:* ****:*:.***.:*:*: *:*** . :*:.:.*. : .. . : * *.:: *:::******..:*: .***:*********::*.:**: **:*::", "identical_positions": 139, "similar_positions": 143, "identity": "35.28%" }, { "cls_id": "homologset.agr.MGI:1289341", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9PT66-1", "uniprot_id": "E9PT66_RAT", "id": "E9PT66-1", "name": "Splicing factor 3B subunit 3", "aln": "---------------------------------------------------------MFLYNLTLQRATGISFAIHGNFS----GTKQQEIVVSRGKILELLRPDPNTGKVHTLLTVE-VFGVIRSLMAFRLTGG--------TKDYIVVGSDSG--RIVILEYQPSKNMFEKIHQETFGKSGCRRIVPGQFLAVDPKGRAVMISAIEKQKLVYILNRDAAARLTISSPLEAHKANTLVYHVVGVDVGFENPMFACLEMDYEEADNDPTGEAAANTQQTLTFYELDLGLNHVVRKYSEPLEEHGNFLITVPGGSDG-------------------PSGVLICSENYITYKNFGDQPDIRCPIPRRRNDLDDPERGMIFVCSATHKTKSMFFFLAQTEQGDIFKITLETDEDMVT--EIRLKYFDTVPVAAAMCVLKTGFLFVASEFGNHYLYQIAHLGDDDEEPEFSSAMPLEEGDTFFFQPRPLKNLVLVDELDSLSPILFCQIADLANEDTPQLYVACGRGPRSSLRVLRHGLEVSEMAVSELPGNPNAVWTVRR-HIEDEFDAYIIVSFVNATLVLSIG-ETVEEVT------DSGFLGTTPTLSCSLLGDDALVQVYPDGIRHIRADKRVN-----EWKTPGKKTIVKCAVNQRQVVIALTGGELVYFEMDPSGQLNEYTERKEMSADVVCMSLANVPPGEQRSRFLAVGLVDNTVRIISLD--PSDCLQPLSMQALPAQPESLCIVEMGGTE-------KQDELGERG--SIGFLYLNIGLQNGVLLRTVLDPVTGDLSDTRTRYLGSRPVKLFRVRMQGQEAVLAMSSRSWLSYSYQSRFHLTPLSYETLEFASGFASEQCPEGIVAISTNTLRILALEKLGAVFNQVAFPLQYTPRKFVIHPESNNLIIIETDHN----AYTEATKAQRKQQMAEEMVEAAGEDERELAAEMAAAFLNENLPESIFGAPKAGNGQWASVIRVMNPIQGNTLDLVQLEQN----EAAFSVAVCRFSNTGE-DWYVLVGVAKDLILSPRSVAGGFVYTYKLVNNGE----KLEFLHKTPVEEVPAAIAPFQGRVLIGVGKLLRVYDLGKKKLLRKCENKH---IANYISGIQTIGHRVIVSDVQESFIWVRYKRNENQLIIFADDTYPRWVTTASLLDYDTVAGADKFGNICVVRLPPNTNDEVDEDPTG-----------NKALWDRGLLN--GASQKAEVIMNYHVGETVLSLQKTTLIPGGSE-SLVYTTLSGGIGILVPFTSH---------------EDHDFFQHVEMHLRSEHP------------------------------PLCGRDHLSFRSYYFPVKNVIDGDLCEQFNSMEPNKQKNVSEELDRTP-PEVSKKLEDIRTRYAF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q921M3-1", "uniprot_id": "SF3B3_MOUSE", "id": "Q921M3-1", "name": "Splicing factor 3B subunit 3", "aln": "---------------------------------------------------------MFLYNLTLQRATGISFAIHGNFS----GTKQQEIVVSRGKILELLRPDPNTGKVHTLLTVE-VFGVIRSLMAFRLTGG--------TKDYIVVGSDSG--RIVILEYQPSKNMFEKIHQETFGKSGCRRIVPGQFLAVDPKGRAVMISAIEKQKLVYILNRDAAARLTISSPLEAHKANTLVYHVVGVDVGFENPMFACLEMDYEEADNDPTGEAAANTQQTLTFYELDLGLNHVVRKYSEPLEEHGNFLITVPGGSDG-------------------PSGVLICSENYITYKNFGDQPDIRCPIPRRRNDLDDPERGMIFVCSATHKTKSMFFFLAQTEQGDIFKITLETDEDMVT--EIRLKYFDTVPVAAAMCVLKTGFLFVASEFGNHYLYQIAHLGDDDEEPEFSSAMPLEEGDTFFFQPRPLKNLVLVDELDSLSPILFCQIADLANEDTPQLYVACGRGPRSSLRVLRHGLEVSEMAVSELPGNPNAVWTVRR-HIEDEFDAYIIVSFVNATLVLSIG-ETVEEVT------DSGFLGTTPTLSCSLLGDDALVQVYPDGIRHIRADKRVN-----EWKTPGKKTIVKCAVNQRQVVIALTGGELVYFEMDPSGQLNEYTERKEMSADVVCMSLANVPPGEQRSRFLAVGLVDNTVRIISLD--PSDCLQPLSMQALPAQPESLCIVEMGGTE-------KQDELGERG--SIGFLYLNIGLQNGVLLRTVLDPVTGDLSDTRTRYLGSRPVKLFRVRMQGQEAVLAMSSRSWLSYSYQSRFHLTPLSYETLEFASGFASEQCPEGIVAISTNTLRILALEKLGAVFNQVAFPLQYTPRKFVIHPESNNLIIIETDHN----AYTEATKAQRKQQMAEEMVEAAGEDERELAAEMAAAFLNENLPESIFGAPKAGNGQWASVIRVMNPIQGNTLDLVQLEQN----EAAFSVAVCRFSNTGE-DWYVLVGVAKDLILSPRSVAGGFVYTYKLVNNGE----KLEFLHKTPVEEVPAAIAPFQGRVLIGVGKLLRVYDLGKKKLLRKCENKH---IANYISGIQTIGHRVIVSDVQESFIWVRYKRNENQLIIFADDTYPRWVTTASLLDYDTVAGADKFGNICVVRLPPNTNDEVDEDPTG-----------NKALWDRGLLN--GASQKAEVIMNYHVGETVLSLQKTTLIPGGSE-SLVYTTLSGGIGILVPFTSH---------------EDHDFFQHVEMHLRSEHP------------------------------PLCGRDHLSFRSYYFPVKNVIDGDLCEQFNSMEPNKQKNVSEELDRTP-PEVSKKLEDIRTRYAF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15393-1", "uniprot_id": "SF3B3_HUMAN", "id": "Q15393-1", "name": "Splicing factor 3B subunit 3", "aln": "---------------------------------------------------------MFLYNLTLQRATGISFAIHGNFS----GTKQQEIVVSRGKILELLRPDPNTGKVHTLLTVE-VFGVIRSLMAFRLTGG--------TKDYIVVGSDSG--RIVILEYQPSKNMFEKIHQETFGKSGCRRIVPGQFLAVDPKGRAVMISAIEKQKLVYILNRDAAARLTISSPLEAHKANTLVYHVVGVDVGFENPMFACLEMDYEEADNDPTGEAAANTQQTLTFYELDLGLNHVVRKYSEPLEEHGNFLITVPGGSDG-------------------PSGVLICSENYITYKNFGDQPDIRCPIPRRRNDLDDPERGMIFVCSATHKTKSMFFFLAQTEQGDIFKITLETDEDMVT--EIRLKYFDTVPVAAAMCVLKTGFLFVASEFGNHYLYQIAHLGDDDEEPEFSSAMPLEEGDTFFFQPRPLKNLVLVDELDSLSPILFCQIADLANEDTPQLYVACGRGPRSSLRVLRHGLEVSEMAVSELPGNPNAVWTVRR-HIEDEFDAYIIVSFVNATLVLSIG-ETVEEVT------DSGFLGTTPTLSCSLLGDDALVQVYPDGIRHIRADKRVN-----EWKTPGKKTIVKCAVNQRQVVIALTGGELVYFEMDPSGQLNEYTERKEMSADVVCMSLANVPPGEQRSRFLAVGLVDNTVRIISLD--PSDCLQPLSMQALPAQPESLCIVEMGGTE-------KQDELGERG--SIGFLYLNIGLQNGVLLRTVLDPVTGDLSDTRTRYLGSRPVKLFRVRMQGQEAVLAMSSRSWLSYSYQSRFHLTPLSYETLEFASGFASEQCPEGIVAISTNTLRILALEKLGAVFNQVAFPLQYTPRKFVIHPESNNLIIIETDHN----AYTEATKAQRKQQMAEEMVEAAGEDERELAAEMAAAFLNENLPESIFGAPKAGNGQWASVIRVMNPIQGNTLDLVQLEQN----EAAFSVAVCRFSNTGE-DWYVLVGVAKDLILNPRSVAGGFVYTYKLVNNGE----KLEFLHKTPVEEVPAAIAPFQGRVLIGVGKLLRVYDLGKKKLLRKCENKH---IANYISGIQTIGHRVIVSDVQESFIWVRYKRNENQLIIFADDTYPRWVTTASLLDYDTVAGADKFGNICVVRLPPNTNDEVDEDPTG-----------NKALWDRGLLN--GASQKAEVIMNYHVGETVLSLQKTTLIPGGSE-SLVYTTLSGGIGILVPFTSH---------------EDHDFFQHVEMHLRSEHP------------------------------PLCGRDHLSFRSYYFPVKNVIDGDLCEQFNSMEPNKQKNVSEELDRTP-PEVSKKLEDIRTRYAF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LVE8-1", "uniprot_id": "SF3B3_DANRE", "id": "Q1LVE8-1", "name": "Splicing factor 3B subunit 3", "aln": "---------------------------------------------------------MFLYNITLQRATGISHAIHGNFS----GTKQQEIVVSRGKILELLRPDANTGKVHTLLTME-VFGVVRSLMAFRLTGG--------TKDYVVVGSDSG--RIVILEYHPSKNMFEKIHQETFGKSGCRRIVPGQFLAVDPKGRAVMIGATEKQKLVYILNRDAAARLTISSPLEAHKANTLVYHVVGVDVGFENPMFACLEMDYEEADNDPTGEAAANTQQTLTFYELDLGLNHVVRKYSEALEEHGNFLITVPGGSDG-------------------PSGVLICSENYITYKNFGDQPDIRCPIPRRRNDLDDPERGMIFVCSATHKTKSMFFFLAQTEQGDIFKVTLETDEEMVT--EIRMKYFDTIPVATAMCVLKTGFLFVSSEFGNHYLYQIAHLGDDDEEPEFSSAMPLEEGDTFFFQPRPLKNLVLVDEQESLSPIMSCQIADLANEDTPQLYVACGRGPRSTLRVLRHGLEVSEMAVSELPGNPNAVWTVRR-HVEDEFDAYIIVSFVNATLVLSIG-ETVEEVT------DSGFLGTTPTLSCSLLGEDALVQVYPDGIRHIRADKRVN-----EWKTPGKKTIIRCAVNQRQVVIALTGGELVYFEMDPSGQLNEYTERKEMSADVVCMSLANVPPGEQRSRFLAVGLVDNTVRIISLD--PSDCLQPLSMQALPAQPESLCIVEMGGVE-------KQDELGEKG--TIGFLYLNIGLQNGVLLRTVLDPVTGDLSDTRTRYLGSRPVKLFRVRMQGQEAVLAMSSRSWLSYSYQSRFHLTPLSYETLEYASGFASEQCPEGIVAISTNTLRILALEKLGAVFNQVAFPLQYTPRKFVIHPETNNLILIETDHN----AYTEATKAQRKQQMAEEMVEAAGEDERELAAEMAAAFLNENLPEAIFGAPKAGSGQWASLVRLINPIQGNTLDLVQLEQN----EAAFSVAICRFLNGGD-DWYVLVGVARDMILNPRSVGGGYIYTYRIVGGGD----KLEFLHKTPVEDVPLAIAPFQGRVLVGVGKLLRIYDLGKKKLLRKCENKH---VPNLVTGIHTIGQRVIVSDVQESLFWVRYRRNENQLIIFADDTYPRWITTACLLDYDTMASADKFGNICVVRLPPNTSDDVDEDPTG-----------NKALWDRGLLN--GASQKAEIIINYHIGETVLSLQKTTLIPGGSE-SLVYTTLSGGIGILVPFTSH---------------EDHDFFQHLEMHMRSEFP------------------------------PLCGRDHLSFRSYYFPVKNVIDGDLCEQFNSMDPHKQKSVSEELDRTP-PEVSKKLEDIRTRYAF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W0M7-1", "uniprot_id": "SF3B3_DROME", "id": "Q9W0M7-1", "name": "Splicing factor 3B subunit 3", "aln": "---------------------------------------------------------MYLYNLTLQKATGVTHAVHGNFS----GGKQQEVLLSRGKSLELLRPDSNTGKVHTLLSTE-IFGCVRALMAFRLTGG--------TKDYIVVGSDSG--RIVILEYNPSKNALEKVHQETFGKSGCRRIVPGQYFAIDPKGRAVMIGAVEKQKLAYIMNRDTQARLTISSPLEAHKSNTLTYHMVGVDVGFDNPMFACLEIDYEEADMDPSGDAAQRTQQTLTFYELDLGLNHVVRKYSEPLEEHANFLVSVPGGNDG-------------------PSGVLICSENYLTYKNLGDQHDIRCPIPRRRNDLDDPERGMIFICSATHRTKSMYFFLLQTEQGDIFKITLETDDDVVS--EIKLKYFDTVPPATAMCVLKTGFLFVASEFGNHYLYQIAHLGDDDDEPEFSSAMPLEEGETFFFAPRALKNLVLVDELPSFAPIITSQVADLANEDTPQLYVLCGRGPRSTLRVLRHGLEVSEMAVSELPGNPNAVWTVKK-RADDEFDAYIIVSFVNATLVLSIG-ETVEEVT------DSGFLGTTPTLCCAALGDDALVQVYPDGIRHIRSDKRVN-----EWKAPGKKSITKCAVNQRQVVITLSGRELVYFEMDPTGELNEYTERSEMPAEIMCMALGTVPEGEQRSWFLAVGLADNTVRILSLD--PNNCLTPCSMQALPSPAESLCLVEMGHTESTTQGGLDDDAPAQRSGNNKGTIYLNIGLSNGVLLRTVLDPVSGDLADTRTRYLGSRPVKLFRIKMQGSEAVLAMSSRTWLSYYHQNRFHLTPLSYETLEYASGFSSEQCSEGIVAISTNTLRILALEKLGAVFNQVAFPLQYTPRTFVIHPDTGRMLIAETDHN----AYTEDTKSARKEQMAEEMRSAAGDEERELAREMANAFINEVLPEDVFSSPKAGLGLWASQIRCLDAMHGQTMFSVPLTQN----EAIMSMAMLKFSIAADGRYYLAVGIAKDLQLNPRISQGGCIDIYKIDPTCS----SLEFMHRTDIDEIPGALCGFQGRLLAGCGRMLRIYDFGKKKMLRKCENKH---IPYQIVNIQAMGHRVYVSDVQESVFFIRYRRAENQLIIFADDTHPRWVTATTLLDYDTIAIADKFGNLSIQRLPHSVTDDVDEDPTG-----------TKSLWDRGLLS--GASQKSENICSFHVGEIIMSLQKATLIPGGSE-ALIYATLSGTVGAFVPFTSR---------------EDYDFFQHLEMHMRNENP------------------------------PLCGRDHLSYRSSYYPVKNVLDGDLCEQYLSIEAAKQKSIAGDMFRTP-NQICKKLEDIRTRYAF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04693-1", "uniprot_id": "RSE1_YEAST", "id": "Q04693-1", "name": "Pre-mRNA-splicing factor RSE1", "aln": "MWGGGKMAVVSLSPHTAKMRKLFGQASTTMAYDGLKREAERRTRSDHNITMVAKDDELYLYHLTLKKQTNFVHSCIGHFVDLEAGSKREQSQLCVATETHLELYDTADGELKLIAKFQNLFATITSMKSLDLPHSGSRAKASNWPTFLALTSDSGNLSIVQIIMHAGALRLKTLVNQPLTRTTLRRVSPISYMEIDPNGRCIILSSVEQNKLCFLV--DYAQKLRISSPLEIIRPHMVTLDMAVVDVNFNNPCFVTLEID----------NAATQLSVHLIFYVLELGLNHIVKKADYLVNPSANFVLSLPDLSRYNITTSLSDNNYDADYDTLFNPFVVIGFENHILVKDMNGFFSLKVEIPKR-SITNSRHKNVTIISGIVQKLKNDFFVLLQSNHGDLFKLTVSPDTNDRNRPLVQLSYFDTIQNSHQLHIFKNGYLFALSEMNNNFLFQFEKLGVEKNDFSNVLTSKDPNKSLVFEPSIKLQNLSILSQQLNLNPSIKSQIVSDS-----PLSIATKHFTNNKIITLTNAVNYSNLISTSLPPNATKLWLIPDPATTGDNNTLLFITFPKKTMILQIDNESMEELTPDEATRSAFKLSQDTTIHTCLMGSHSIIQVCTAELRHIVPTGKSRYSNKLTWVPPAGIRIVCATSSKTQLIISLSNYELVYFKIDVSS--DSLIELTTHPELDTMPSKVAIVQDTQHADLLAIADNEGMIKIMSLKDQKEDFLTVISLQLVSEKISDMIMVRD---------------------SSIGQLNLHVGLENGVYMKFHIGDVDGSFTDIKRRFLGLKPVSLSYLREIS--VSLNNEEEEEEEEDDDDEKEEEEINSSGAKWMSCVVCHSSSTWVSYTWKNVWTIRQLKDQNMLSCSKFVNADVAINGVCSISSSGRLNIGRVSNFPTLDNWFHVHESSVNKQENGGGDESNEEEEDEMEEEMEMLQISTFRPRTILSFPNN-----PKSILFIDNHSGKKQCRISLQIDGECLKFGSSDHLYKILDDIDCVSAAIIDFTRQADHLIICAGDKRLLTYKILVNKDKLSFDIELLHQTEIISPIHAMLKFKNFLLTAMGSTIVLYGLGKKQLLRRSVTQTPVSITKIVSMHQWNYERLAVGDIHESVTLFIWDPAGNVFIPYVDDSVKRHVTVLKFLDEATVIGADRYGNAWTLRSPPECEKIMSNHDPSELSNGAIKYPLDVITLQQKLPNTYDCKFKFQLLNHFFVNDIITDFHILDSLSNSDRPGCIYMGLQGTVGCFIPLLSKGNVFMMGNIENIMAEADDTFYLDYESRKKNNNMRKEDDEEESGSVVLQGRHGIEDEIICEGSCSILGRDHQEYRSYYAPVRKVIDGDLCENFLRLSLNEQEFLAKNLKSVQVEDIIQTINEVRTNYM-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::**::**:: *.. .: *:* * *::: :. .. .* *. *::: : . : :*. : :: :: *. . ::.: **** ** : :.. ::.: ::.: :: **: * .:: :**:**.:::.: *::** ::: * :* ****** :.: :. .:. ***.*:** *. **:* :** . . * ** *:*****:*:* . :: .**::::*. . . *:* **:: *::.. .:: **:* . :. .:.: ::.. .:: *. :*.* *:::**:**:*:..* : . :::.****: : : ::*.*:**. **:.*::*:*: :** :.:: . : : . .* . *:** ::.: .: * : .*:.. : * : : ....: .* :.:: *:: :.** *.. :* : .: :: ::::* : *::*.*. *::**:* .: *. .*: . :*..:::** . :*** . : . * .*. * .: .: *::*:*:. *****::* :. :. * . . : : . *:: :**:. :. ::*:**. .: * *:* :. ..: :*. . * : *::**.*** :: :. * *.::* : *:** :**.* :: . . * ... . :.. . :. . :: * . ..... : .*. * *:. . : . . : : . . ..:..: : ...: : . :: ::* .: ::* *: ** :. *. ::. *: .. : :: *:. : * : : * : :: : :..::: . : *:: . .:*::*:* : . *: *:. :* . * : :*.:***::**:. .: :. : : .*: *.*::**. . : * :* :.**: * :*. :** *: **::** * * . . :.:. .. :: * . ... * : : :.:.: : .:: :..... . :* *.* :* ::*: *: * *: . * : :.: .: **** .:** * **::*:******:: :. :*: :: :: . :: :.::::**.* ", "identical_positions": 245, "similar_positions": 498, "identity": "17.38%" }, { "cls_id": "homologset.agr.MGI:1298204", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P45479-1", "uniprot_id": "PPT1_RAT", "id": "P45479-1", "name": "Palmitoyl-protein thioesterase 1", "aln": "MASPGYRRLLAAA--LLPWCCAAWALGHLDP------PSPPPLVIWHGMGDSCCNPMSMGSIKKMVEKEIPGIYVLSLEIGKNMVEDVENSFFLNVNLQVGMACQILEKDPKLQHGYNAIGFSQGGQFLRAVAQRCPTPPMMTLISVGGQHQGVFGLPRCPGESSHICDFIRKSLNAGAYSKVVQERLVQAQYWHDPIKEEVYRNCSIFLADINQERHINESYKENLMALKKFVMVKFFNDSIVDPVDSEWFGFYRSGQAKETIPLQETTLYTEDRLGLKKMDKAGKLVFLAKEGDHLQISKEWFTAHIIPFLK--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88531-1", "uniprot_id": "PPT1_MOUSE", "id": "O88531-1", "name": "Palmitoyl-protein thioesterase 1", "aln": "MASSCSRRLLAAA--LLPWCCAAWALGHLDP------PSPPPLVIWHGMGDSCCNPMSMGVIKKMVEKEIPGIYVLSLEIGKNMMEDVENSFFLNVNVQVNMVCQILEKDPKLQQGYNAIGFSQGGQFLRAVAQRCPTPPMMTLISVGGQHQGVFGLPRCPGESSHICDFIRKSLNAGAYSKLVQERLVQAQYWHDPIKESVYRNYSIFLADINQERCVNESYKKNLMALKKFVMVKFFNDSIVDPVDSEWFGFYRSGQAKETIPLQESTLYTEDRLGLKKMDKAGKLVFLAKEGDHLQISKEWFTAHIIPFLK--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P50897-1", "uniprot_id": "PPT1_HUMAN", "id": "P50897-1", "name": "Palmitoyl-protein thioesterase 1", "aln": "MASPGCLWLLAVA--LLPWTCASRALQHLDP------PAPLPLVIWHGMGDSCCNPLSMGAIKKMVEKKIPGIYVLSLEIGKTLMEDVENSFFLNVNSQVTTVCQALAKDPKLQQGYNAMGFSQGGQFLRAVAQRCPSPPMINLISVGGQHQGVFGLPRCPGESSHICDFIRKTLNAGAYSKVVQERLVQAEYWHDPIKEDVYRNHSIFLADINQERGINESYKKNLMALKKFVMVKFLNDSIVDPVDSEWFGFYRSGQAKETIPLQETSLYTQDRLGLKEMDNAGQLVFLATEGDHLQLSEEWFYAHIIPFLG--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1R8J6-1", "uniprot_id": "F1R8J6_DANRE", "id": "F1R8J6-1", "name": "Palmitoyl-protein thioesterase 1", "aln": "MAPSAAFRLLSVSGCLLLLCGTSWASN-----------GTVPLVIWHGMGDSCCNPLSMGAIKKMVEQEVSGIYVLSLMIGKSVFEDTENGFLMDVNKQVSFVCDQLAKDPKLKEGYNAMGFSQGAQFLRAVAQRCPDPPMRNLISVGGQHQGVYGLPRCPGESSHICDWIRKQLNSGAYTDAVQKHLVQAQYWHDPLNDDLYKKYSLFLADINQERVVNETYKKNLMSLNKFVMVKFLQDSIVDPVDSEWFGFYKAGQAEELETLQESPIYKEDRLGLAAMDSAGKLVFLASEGDHLQFTREWFNENLLSYLL--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W3C7-1", "uniprot_id": "PPT1_DROME", "id": "Q9W3C7-1", "name": "Palmitoyl-protein thioesterase 1", "aln": "MISICCSRFSCILFLLFLIFSLVLSYIWWSPTKGGTNPEVLPVVLWHGMGDTCCVPFSLGAIMNLIVEQTKGGYVRSLQIGGNVLIDWQSGFFIHPNEQVDYVCKQLLQDEHLAKGYHAIGFSQGGQFLRAVAERCPNPPMRNLITLGGQHQGIFGLPMCPTLTEKPCDYITRLLDNAAYAPEVQKALVQATYWHDPIMENKYRLGSTFLADINNELFINKFYIENLQKLKKFVMVQFLNDTIVQPKESQWFQYYTTGQNKVIQPFTESKVYQD--LGLDKMHRQGQLVFLGVEGDHLAISKAWFIQNIVPLLLEK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . : . *: : *:*:******:** *:*:* * ::: :: * ** ** ** .:. * :..*::. * ** .*. * :* :* .**:*:*****.*******:*** *** .**::******::*** ** :.: **:* : *: .**: **: **** *****: :. *: * ******:* :*: * :** *:*****:*::*:**:* :*:** :* :** : .: *: :* : *** *. *:****. ***** ::. ** :::. * ", "identical_positions": 132, "similar_positions": 81, "identity": "41.77%" }, { "cls_id": "homologset.agr.MGI:1298205", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Y1A7-1", "uniprot_id": "Q9Y1A7_DROME", "id": "Q9Y1A7-1", "name": "", "aln": "-----MARVQASDSLIPRQVFEVP---------------PAEPNNS--------------TADSG-SQGSGVKLKKQIGLLDGVAIIVGVIVGSGIFVSPKGVLKFSG-SIGQSLIVWVLSGVLSMVGALCYAELGTMIPKSGGDYAYIGTAFGPLPAFLYLWVALLILVPTGNAITALTFAIYLLKPFWP-SCDAPIEAVQLLAAAMICVLTLINCYNVKWVTRVTDIFTGTKVVALLVIVGAGVWWLFD----GNTEHWDN--PFSGG-LQDPGYIALAFYSGLFSYSGWNYLNFVTEELKDPYRNLPKAICISMPVVTVIYMITNIAYFSVLSPDEILSS-DAVAVTFGDKMLG--YMSWIMPFAVACSTFGSLNGAIFASSRLFFVGARNGHLPAAISLINVNCLTP----VPSLIFLGVLTLLLLFI-EDVYVLIN-YVSYVEALFTLISVSGLLWMRYKQP----KTERPIKVNLALPIIYLIVCLFLVIFSCTQT----------PYVVGIGTIIILSGIPVYYL--TIHKPVKWLADTSQAINLWCSKFFICMPNQEKFD------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VB75-1", "uniprot_id": "Q9VB75_DROME", "id": "Q9VB75-1", "name": "", "aln": "-----MPAADELQSPSSEMVLLTPSSGNPPSSIAQPAANPAEKAQC--------------REGSAESDSSRVVIKKQLGLLEGVAIILGIIFGSGIFVSPKGVIREVE-SVGASLVIWVLCGLLSMIGALCYAELGTAIPKSGGDYAYIFEAYGSLPAFLYLWDAMMIFVPTTNAIMGLTFASYVLEPFFGGACEIPKIALQLLAAITICFLTYLNSYYMKVTTKMQNVIMFTKIAALVLIILVGLVWMMM----GNVENFTR--PFDNT-ETDPGKMSVAFYSGIFSYAGWNYLNFMTEELRDPYRNLPRAIYISLPLVTGIYVLANVAYLAVLSPSEMIAS-NAIAVTFGDKILG--VFSLIIPLMVAISAFGGLSVHIMTSSRICFVGARNGHMPAILSHISVKSYTP----LPSLVFLCFLSIVMLVV-SDVYVLIT-YASIVESFFIMLSVSAVLYFRYTRP----CMERPIKVAMWIPALFVIVCAFLVVVPIYVA----------PYEVGMGVLITIIGIPFYYVGVVWKNKPKWVQSTIDSVTFTCQKLFMSAK-EEKED------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9Z127-1", "uniprot_id": "LAT1_MOUSE", "id": "Q9Z127-1", "name": "Large neutral amino acids transporter small subunit 1", "aln": "---------MAVAGAKRRAVATPAAAAAEEERQAREKMLEARRGDG----------------ADP--EGEGVTLQRNITLLNGVAIIVGTIIGSGIFVTPTGVLKEAG-SPGLSLVVWAVCGVFSIVGALCYAELGTTISKSGGDYAYMLEVYGSLPAFLKLWIELLIIRPSSQYIVALVFATYLLKPVFP-TCPVPEEAAKLVACLCVLLLTAVNCYSVKAATRVQDAFAAAKLLALALIILLGFIQMGKDMGQGDASNLQQKLSFEGT-NLDVGNIVLALYSGLFAYGGWNYLNFVTEEMINPYRNLPLAIIISLPIVTLVYVLTNLAYFTTLSTNQMLTS-EAVAVDFGNYHLG--VMSWIIPVFVGLSCFGSVNGSLFTSSRLFFVGSREGHLPSVLSMIHPQLLTP----VPSLVFTCIMTLMYAFS-RDIFSIIN-FFSFFNWLCVALAIIGMMWLRFKKP----ELERPIKVNLALPVFFILACLFLIAVSFWKT----------PMECGIGFAIILSGLPVYFFGVWWKNKPKWILQAIFSVTVLCQKLMQVVPQET---------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63016-1", "uniprot_id": "LAT1_RAT", "id": "Q63016-1", "name": "Large neutral amino acids transporter small subunit 1", "aln": "---------MAVAGAKRRAVAAPATTAAEEERQAREKMLEARRGDG----------------ADP--EGEGVTLQRNITLINGVAIIVGTIIGSGIFVTPTGVLKEAG-SPGLSLVVWAVCGVFSIVGALCYAELGTTISKSGGDYAYMLEVYGSLPAFLKLWIELLIIRPSSQYIVALVFATYLLKPVFP-TCPVPEEAAKLVACLCVLLLTAVNCYSVKAATRVQDAFAAAKLLALALIILLGFIQMGKDIGQGDASNLHQKLSFEGT-NLDVGNIVLALYSGLFAYGGWNYLNFVTEEMINPYRNLPLAIIISLPIVTLVYVLTNLAYFTTLSTNQMLTS-EAVAVDFGNYHLG--VMSWIIPVFVGLSCFGSVNGSLFTSSRLFFVGSREGHLPSILSMIHPQLLTP----VPSLVFTCVMTLMYAFS-RDIFSIIN-FFSFFNWLCVALAIIGMMWLRFKKP----ELERPIKVNLALPVFFILACLFLIAVSFWKT----------PLECGIGFAIILSGLPVYFFGVWWKNKPKWILQVIFSVTVLCQKLMQVVPQET---------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q01650-1", "uniprot_id": "LAT1_HUMAN", "id": "Q01650-1", "name": "Large neutral amino acids transporter small subunit 1", "aln": "---------MAGAGPKRRALAAP---AAEEKEEAREKMLAAKSADG----------------SAPAGEGEGVTLQRNITLLNGVAIIVGTIIGSGIFVTPTGVLKEAG-SPGLALVVWAACGVFSIVGALCYAELGTTISKSGGDYAYMLEVYGSLPAFLKLWIELLIIRPSSQYIVALVFATYLLKPLFP-TCPVPEEAAKLVACLCVLLLTAVNCYSVKAATRVQDAFAAAKLLALALIILLGFVQIGK----GDVSNLDPNFSFEGT-KLDVGNIVLALYSGLFAYGGWNYLNFVTEEMINPYRNLPLAIIISLPIVTLVYVLTNLAYFTTLSTEQMLSS-EAVAVDFGNYHLG--VMSWIIPVFVGLSCFGSVNGSLFTSSRLFFVGSREGHLPSILSMIHPQLLTP----VPSLVFTCVMTLLYAFS-KDIFSVIN-FFSFFNWLCVALAIIGMIWLRHRKP----ELERPIKVNLALPVFFILACLFLIAVSFWKT----------PVECGIGFTIILSGLPVYFFGVWWKNKPKWLLQGIFSTTVLCQKLMQVVPQET---------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IFJ3-1", "uniprot_id": "A0A0R4IFJ3_DANRE", "id": "A0A0R4IFJ3-1", "name": "", "aln": "-----------MSGLKKRSSNAS-TERDEDDKQVTEKMLTGRGGNGNTSPSGDITPGSPSTDISPADGEETVVLKRTITLVNGVAIIVGTIIGSGIFVTPTGVVKEAG-SVGLSLVVWTVCGVFSTIGALCYAELGTTITKSGGDYAYILEVYGSLPAFLKLWIELLIIRPSSQYIVAYVFATYILKPIFP-VCPVPETGAKLVACLCILLLTAVNCYSVKAATRVQDAFAAAKLLALGLIIIIGFVEIGK----GDTVELLPENSFKGS-NTDFGNIGLALYSGLFAYGGWNYLNFVTEEMIEPYKNLPRAIIISLPIVTVVYVLTNLAYFTTLSPEKMLSS-EAVAVDFGNYHLG--PMAWIIPVFVGLSCFGSVNGSLFTSSRLFFVGSREGHLPSLLSMIHPDLLTP----LPSLIFTCIMTLLYAFS-NDIFSVIN-FFSFFNWLCIAMAIVGMMWLRYKKP----ELERPIKVNILLPIVFVLACLFLIVVSFWKT----------PVECAIGFGIIATGVPVYFFGVWWQTKPKWLLQIIFSSTVMCQKMMEVVPQES---------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VKC2-1", "uniprot_id": "Q9VKC2_DROME", "id": "Q9VKC2-1", "name": "", "aln": "-----------MTDRYANGVTTS---------LVEPTNGCAAPGNP-----------------NPADGEEKIVLKRKLTLINGVAIIVGTIIGSGIFIAPTGVFIYTE-SVGSSLLIWLTCGILSTIGALCYAELGTCITRSGGDYAYLLVSFGPLVGFLRLWIALLIIRPTTQTIVALSFAHYAVKPFFP-ECDPPQNAVKLLAAICLTLLTTINCLSVKVSMKVQDVFTVGKLLALIMIILSGLYYMAT----GELENFRN--PWEGI-YTAR-NIGYAFYSGLFAFGGWNYLNFVTEELQDPYKNLPRAIWIAMPLVTSIYVLVNLAYFAVVNKPEMLSS-LAVAVTFGNRVFG--PLAFMVPIFVALSTFGGVNGVLFTSARLFATGAQEGHLPKFFQLFHVKQQTP----IPSLIFTCLMSLLMLLT-DNVYQLIN-YFSSVLWLSVVASIAGMLWLRHKRP----DLPRPIKVHLALPITFMVSCVTLVLLPNLEE----------PQNLLIGIGITLAGIPFYYAFIARKKKPKCYGRLSNSVVEICRAIFNTTIIESNEAIN----------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P50276-1", "uniprot_id": "MUP1_YEAST", "id": "P50276-1", "name": "High-affinity methionine permease", "aln": "----MSEGRTFLSQLNVFNKENYQFSSSTTKKEVSNSTVDADNGAS-------------DFEAGQQFATELDQGEKQLGILSCIGLICNRMLGTGVFAVSSTIYTLCG-SVGLALIMWAVGAIIAISGLYVYMEFGTAIPKNGGEKNYLEAIFRKPKFFITCMYAAYIFFLGWAAGNSINTAIMFLTAADT---EVTKWNQRGIGVAVVFFAFLINSLNVKIGLYLQNILGIFKIGIVLFISITGWVALGGGLKDGYQSHNFRNAFEGTE-TATAYGIVNALYSVIWSFVGYSNVNYALGEVKNPVRTLKIAGPTSMVFLAIIYIFVNIAYFAVVPKDKLISSKLILAADFFDIVFGG-QAKRAAAALVGLSALGNVLSVIFSQGRIIQQLGREGVLPFSNFFASSKPFNSPMVGLFQHFIVCTVTILAPPP-GDAYLLVQNLISYPMNIINFAISAGLLWIYWQRRQGKIEWNPPIKAGVFVTGFFTLSNLYLIIAPYVPPSNGESVYSSMPYWIHCVIAWGIFFFGGVYYVVWAQLLPRWGHYKLVSKDVLGEDGFWRVKIAKVYDDTIGDVDTQEDGVIETNIIEHYKSEQEKSL", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P38734-1", "uniprot_id": "MUP3_YEAST", "id": "P38734-1", "name": "Low-affinity methionine permease", "aln": "MEPLLFNSGKANPSQDVFIDVEVGDITTKYGSTNTGSFSSMDTVEAQ-------------AIKAETARFMEVPQGRHLGVFSTVVLFVSRIMGSGIFAVPSVILLNTGGNKLIYFAIWVFSAAIAFAGLYLFLEFGSWIPKSGGRKNFLERSFERPRLLISVVFSCYSVLTGYALTGSIVFGKYVLSAFGV----TDDSWSKYVSISFIIFAVLIHGVSVRHGVFIQNALGGLKLIMIVLMCFAGLYTLFFYKSTGQVAWDLPVTQVEKDSLLSVSSIATAFISSFFCFSGWDTVHTVTSEIKNPVKTLKVSGPLSLIICFVCYTMMNVAYLKVLTYEEIVSAGPLVGSVLFTKLFGPRVGGKFIAFSIAISAASNILVVIYSISRVNQEIFKEGYLPFSIHMSKNWPFDAPLPSISLCGFITIAWILILPKEGESFNYLVSMDGYGNQFFLLLVAIGLFIWRFKHK----NEVPEIRASTFGVLAIITLSLYMLMAPFFADPSLNRVGFLPPYQIMSLLVIVAC---FFFWLVKFVLLPKFFHYKLLPKITYLHDGLIVTEWVKKPCLC----------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :.. : :: . :.*:*:* .. : . : :* . :: * : *:*: *.:.** :: : :: . . . : . : :. : . :: :: : : : *: : .: * : * : *: * ::.: *:. :: *: :* :.* : :: . * : *:**: .: ::::: :. : :* . :. * ..: : : .*: ::* :* . : : :: : : : . : .:: : *:. :: . * : : . : ", "identical_positions": 30, "similar_positions": 123, "identity": "5.02%" }, { "cls_id": "homologset.agr.MGI:1298206", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O70172-1", "uniprot_id": "PI42A_MOUSE", "id": "O70172-1", "name": "Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MATPGNLGSSVLASKTKT----KKKHFVAQKVKLFRASDPLLSVLMWGVNH--------------------------------------------------------------------------SINELSHVQIPVM--------LMPDDFKAYSKIKVDNHLFNKE-NMPSHFKFKEYCPMVFRNLRERFGIDDQDFQNSLTRSAPLPND-SQARSGARFHTSYDKRYVIKTITSEDVAEMHNILKKYHQYIVECHGVTLLPQFLGMYRLNVDG--------VEIYVIVTRNVFSHRLSVYRKYDLKGSTVAREASDKEK-----AKELPTLKDNDFINEGQKIYIDDNNKKIFLEKLKKDVEFLAQLKLMDYSLLVGIHDVERAEQE--EVECEEND-GEEEGESDSTHPIGTPPDSPGNTLNSSPPLAPGEFDPNIDVYAIKCHENAPRKEVYFMAIIDILTHYDAKKKAAHAAKTVKHGAGAEISTVNPEQYSKRFLDFIGHIL-----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9R0I8-1", "uniprot_id": "PI42A_RAT", "id": "Q9R0I8-1", "name": "Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MATPSNLGSSVLASKTKT----KKKHFVAQKVKLFRASDPLLSVLMWGVNH--------------------------------------------------------------------------SINELSHVQIPVM--------LMPDDFKAYSKIKVDNHLFNKE-NMPSHFKFKEYCPMVFRNLRERFGIDDQDFQNSLTRSAPLPND-SQARSGARFHTSYDKRYVIKTITSEDVAEMHNILKKYHQYIVECHGVTLLPQFLGMYRLNVDG--------VEIYVIVTRNVFSHRLSVYRKYDLKGSTVAREASDKEK-----AKELPTLKDNDFINEGQKIYIDDSNKKIFLEKLKKDVEFLAQLKLMDYSLLVGIHDVERAEQE--EVECEENE-GEEEGESDGAHPIGTPPDSPGNTLNSSPPLAPGEFDPNIDVYAIKCHENAPRKEVYFMAIIDILTHYDAKKKAAHAAKTVKHGAGAEISTVNPEQYSKRFLDFIGHILT----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P48426-1", "uniprot_id": "PI42A_HUMAN", "id": "P48426-1", "name": "Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MATPGNLGSSVLASKTKT----KKKHFVAQKVKLFRASDPLLSVLMWGVNH--------------------------------------------------------------------------SINELSHVQIPVM--------LMPDDFKAYSKIKVDNHLFNKE-NMPSHFKFKEYCPMVFRNLRERFGIDDQDFQNSLTRSAPLPND-SQARSGARFHTSYDKRYIIKTITSEDVAEMHNILKKYHQYIVECHGITLLPQFLGMYRLNVDG--------VEIYVIVTRNVFSHRLSVYRKYDLKGSTVAREASDKEK-----AKELPTLKDNDFINEGQKIYIDDNNKKVFLEKLKKDVEFLAQLKLMDYSLLVGIHDVERAEQE--EVECEEND-GEEEGESDGTHPVGTPPDSPGNTLNSSPPLAPGEFDPNIDVYGIKCHENSPRKEVYFMAIIDILTHYDAKKKAAHAAKTVKHGAGAEISTVNPEQYSKRFLDFIGHILT----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0UXW0-1", "uniprot_id": "B0UXW0_DANRE", "id": "B0UXW0-1", "name": "Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASAASSLAASIASKTKTEKKKKKQHFVSQKVKLFRASDPLLSVLMWGVNH--------------------------------------------------------------------------SINELRHIQIPVM--------LMPDDFKANSKIKVDNHLFNKE-NMPSHFKFKEYCPLVFRNLRERFSIDDQEYQNSLTRRAPIPSD-AQGRSGARFHTSHNKRYVIKIITSEDVAEMHNILKKYHQYIVECHGNTLLPQFLGMYRLTVDG--------DETYMIVTRNVFSHRLPVYKKYDLKGSTVAREASDKEK-----TKELPTYKDNDFINDGQKICIDDENKKMFLEKLKNDVEFLAQLKLMDYSLLVGIHDVERGEQEQPEEESEDNDAGEEEGTESDGGATGSPPDSPSNTLDSNRPLGPGEFDPIIDVYAIKSHENAPKKEIYFMAVIDILTPYDAKKKAAHAAKTVKHGAGAEISTVNPEQYSKRFYDFITTILS----------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P38994-1", "uniprot_id": "ITS3_YEAST", "id": "P38994-1", "name": "Phosphatidylinositol 4-phosphate 5-kinase MSS4", "aln": "MSVLRSQPPSVVPLHLTTSTSRKTEQEPSLLHSAIIERHQDRSVPNSNSNPDSNHRIKKDRNNHTSYHSSSNSESNMESPRLSDGESSTPTSIEELNPTINNSRLVKRNYSISIDPLHDNSNNNTDDDHPNTITSPRPNSTSNKEMQKYSFPEGKESKKITTPSLNSNNCLDLDNSSLVHTDSYIQDLNDDHILLNKRVSRRSSRISAVTATSTTIKQRRNTQDSNLPNIPFHASKHSQILPMDDSDVIKLANGDTSMKPNSATKISHSMTSLPLHPLPQPSQKSKQYHMISKSTTSLPPENDHYYQHSRGTNHNHAANAAAVNNNTTTTTAATGLKRSESATAEIKKMRQSLLHKREMKRKRKTFLVDDDRVLIGNKVSEGHVNFIIAYNMLTGIRVAVSRCSGIMKPLTPADFRFTKKLAFDYHGNELTPSSQYAFKFKDYCPEVFRELRALFGLDPADYLVSLTSKYILSELNSPGKSGSFFYYSRDYKYIIKTIHHSEHIHLRKHIQEYYNHVRDNP-NTLICQFYGLHRVKMPISFQNKIKHRKIYFLVMNNLFPPHLDIHITYDLKGSTWGRFTNLDKERLAKDRSYRPVMKDLNWLEEGQKIKFGPLKKKTFLTQLKKDVELLAKLNTMDYSLLIGIHDINKAKED--------------DLQLADTASIEEQPQTQGPIRTGTGTVVRHFFREFEGGIRASDQFNNDVDLIYYVGIIDFLTNYSVMKKLETFWRSLRHDT-KLVSAIPPRDYANRFYEFIEDSVDPLPQKKTQSSYRDDPNQKNYKD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : : . .:. *: *::::... : ..: *.** : * * :::.* * * **: .*: .* * : . ****:*** ***:** *.:* :: *** :.. : .:**: *: * : :*:** * .: .::: :::*:::: : **: ** *::*:.: : *.:* .*:*. :* :: .******* .* :. .:: . *. ** :::::**** :. :** ** :**:***:**:*: ******:****:::.::: : . . *:: . .. .: * . . : * . :*::.:**:** *.. ** ::::*.: :*:: *.:*::** :** : ", "identical_positions": 108, "similar_positions": 145, "identity": "13.58%" }, { "cls_id": "homologset.agr.MGI:1298207", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88634-1", "uniprot_id": "PAR4_MOUSE", "id": "O88634-1", "name": "Proteinase-activated receptor 4", "aln": "-MCWPLLYPLVLGLSISLAEGIQTPSIYDDVESTRGSHEGPLGPTVELKEPKSSDKPNPRGYPGKFCANDSDTLELPASSQALLLGWVPTRLVPALYGLVVAVGLPANGLALWVLATRVPRLPSTILLMNLAVADLLLALVLPPRLAYHLRGQRWPFGEAACRVATAALYGHMYGSVLLLAAVSLDRYLALVHPLRARALRGQRLTTGLCLVAWLSAATLALPLTLHRQTFRLAGSDRMLCHDALPLTEQTSHWRPAFICLAVLGCFVPLLAMGLCYGATLRALAANGQRYSHALRLTALVLFSAVASFTPSNVLLVLHYSNPSPEAWGNLYGAYVPSLALSTLNSCVDPFIYYYVSHEFREKVRA-MLCRQPEASSSSQASREAGSRGTAICSSTLL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q920E0-1", "uniprot_id": "PAR4_RAT", "id": "Q920E0-1", "name": "Proteinase-activated receptor 4", "aln": "-MCWPLLYPLMLGFSISPAE-CQTPSIYDDVESTREGQEASLRPTVELNESKSPDKPNPRGFPGKPCANNSDTLELPASSEALLLGWVPTRLVPAIYGLVVVVGLPANGLALWVLATRVPRLPSTILLMNLAVADLLLALVLPPRLVYHLRGQRWPFGEAACRVATAALYGHMYGSVLLLAAVSLDRYLALVHSLRARALRGQRLTTILCLVAWLSAATLVLPLTFHRQTFLLAGSDRMLCHDALPLAEQTSHWRPAFICLAVLGCFVPLLAMVLCYGATLRALAANGQRYSHAVRLTALVLFSAVAAFTPSNVLLVLHYSNPSPEAWGNLYGAYVPSLALSTLNSCVDPFIYYYVSHEFREKVRA-MLCRQLKASSSSQASREAGSRGTAICSSTLL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96RI0-1", "uniprot_id": "PAR4_HUMAN", "id": "Q96RI0-1", "name": "Proteinase-activated receptor 4", "aln": "MWGRLLLWPLVLGFSLSGGT--QTPSVYDESGSTGGG-----------DDSTPSILPAPRGYPGQVCANDSDTLELPDSSRALLLGWVPTRLVPALYGLVLVVGLPANGLALWVLATQAPRLPSTMLLMNLAAADLLLALALPPRIAYHLRGQRWPFGEAACRLATAALYGHMYGSVLLLAAVSLDRYLALVHPLRARALRGRRLALGLCMAAWLMAAALALPLTLQRQTFRLARSDRVLCHDALPLDAQASHWQPAFTCLALLGCFLPLLAMLLCYGATLHTLAASGRRYGHALRLTAVVLASAVAFFVPSNLLLLLHYSDPSPSAWGNLYGAYVPSLALSTLNSCVDPFIYYYVSAEFRDKVRAGLFQRSPGDTVASKASAEGGSRGMGTHSSLLQ", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **:**:**:*:* . ****:**: ** . .:.... * ***:**: ***:******* **.**************:****:.***************:.******:******.*******.****:.****************:*****************************.********:**: **:.*** **:*.****::**** ** ***:******** *:***:*** ***:****:***** *******::***.*:**.**:****:** **** *.***:**:****:***.******************************* ***:**** :: *. : :*:** *.**** . ** * ", "identical_positions": 281, "similar_positions": 64, "identity": "70.6%" }, { "cls_id": "homologset.agr.MGI:1298208", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O08675-1", "uniprot_id": "PAR3_MOUSE", "id": "O08675-1", "name": "Proteinase-activated receptor 3", "aln": "--MKILILVAAGLLFLPVTVCQSGIN-VSDNSAKPTLTIKSFNGGPQNTFEEFPLSDIEGWTGATTTIKAECPEDSISTLHVNNATIGYLRSSLSTQVIPAIYILLFVVGVPANIVTLWKLSLRTKSISLVIFHTNLAIADLLFCVTLPFKIAYHLNGNNWVFGEVTCRITTVVFYGNMYCAILILTCMGINRYLATAHPFTYQKLPKRSFSMLMCGMVWVMVFLYMLPFVILKQEYHLVHSEITTCHDVVDACESPSSFRFYYFVSLAFFGFLIPFVIIIFCYTTLIHKLKSKDRIWLGYIKAVLLILVIFTICFAPTNIILVIHHANYYYHNTDSLYFMYLIALCLGSLNSCLDPFLYFVMSKVVDQLNP---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q920E1-1", "uniprot_id": "PAR3_RAT", "id": "Q920E1-1", "name": "Proteinase-activated receptor 3", "aln": "MEMKVLILVGVRLLFLPTTVCQSGMKHVSDNSA---LTAESFNGN-EHSFEEFPLSDIEGWTGATTTIKAKCPEESITTLHVNNATMGYLRSSLSTKVIPAIYILVFVIGVPANIVTLWKLSSRTKSICLVIFHTNLAIADLLFCVTLPFKIAYHLNGNDWVFGEVMCRVTTVAFYGNMYCAILILTCMGINRYLATVHPFTYRKLPKRNFTLLMCGVVWVMVVLYMLPLAILKQEYHLVQPGITTCHDVHDTCESPLPFQFYYFVSLAFFGFLIPFVVSVFCYTTLIHKLNAQDRKWLRYIKAVLLILVIFTICFAPTNIILIIHHANYYYSNTDSLYFMYLIALCLGSLNSCLDPFLYFIMSKIVDQLTS---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O00254-1", "uniprot_id": "PAR3_HUMAN", "id": "O00254-1", "name": "Proteinase-activated receptor 3", "aln": "--MKALIFAAAGLLLLLPTFCQSGMENDTNNLAKPTLPIKTFRGAPPNSFEEFPFSALEGWTGATITVKIKCPEESASHLHVKNATMGYLTSSLSTKLIPAIYLLVFVVGVPANAVTLWMLFFRTRSICTTVFYTNLAIADFLFCVTLPFKIAYHLNGNNWVFGEVLCRATTVIFYGNMYCSILLLACISINRYLAIVHPFTYRGLPKHTYALVTCGLVWATVFLYMLPFFILKQEYYLVQPDITTCHDVHNTCESSSPFQLYYFISLAFFGFLIPFVLIIYCYAAIIRTLNAYDHRWLWYVKASLLILVIFTICFAPSNIILIIHHANYYYNNTDGLYFIYLIALCLGSLNSCLDPFLYFLMSKTRNHSTAYLTK-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QQR2-1", "uniprot_id": "F1QQR2_DANRE", "id": "F1QQR2-1", "name": "", "aln": "--MRRVFVPLLLMLIFEDSLQDPASKYSRINTSNYPLNPKTFTGTIESNASQLSNS-----------------SQTQPVINVSANVINHTAGIISTRIIPFAYILAILIGIPSNVFVLACLSGK-KVLSSGILYFSLALSDLLLLFSLTFRVHYHLNNSDWIFGELACKLVTACFYGNIYCSIHAHMCISVMRYFAVVHPFLYRTMRKRFCAIWMSLTIWVVFSIAMAPEFVVQQSFHVSGQELVTCHDIQPYEEASYQALIPYRLSLICIGFVFPSLVIAFIYGSIIYHLNRSSQDWKRYIKASTLVFVIFLVCFAPCNLLLFAHYVKLYTQRQYELYAYYRVAVCLCSFHSCLDPFLSYLLTKTSTSQVKFRSFSSIPLKALSTI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: ::. :*:: :. :.. : * : * ::* * . .::. * .:: . ::*. .:.: . :**::** *:* :::*:*:* ..* * : : :. ::: .**::*:*: .:*.*:: ****..:*:***: *: .*. ****:**:* *:.: **:* .*** *: : *: :: . :*. . : * * :::*.::: :.****: *:. : * :** :**::* :: : * ::* *: .: * *:** *::*** :**** *::*. *:.: * . ** * :*:** *::******* ::::* ", "identical_positions": 100, "similar_positions": 130, "identity": "25.84%" }, { "cls_id": "homologset.agr.MGI:1298209", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JKA7-1", "uniprot_id": "HCN4_RAT", "id": "Q9JKA7-1", "name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDKLPPSMRKRLYSLPQQVGAKAWIMDEEEDGEEEGAGGLQDPSRRSIRLRPLPSPSP------------------------------------------------SVAAGCSESRGAALGAADSEGPGRSAGKSSTNGDCRRFRGSLASLGSRGGGSGGAGGGSSLGHLHDSAE-------------------ERRLIAAEGDASPGEDRTPPGLATEPERPGAAAQPAASPPP----------------------------------------------------QQPPQPASASCEQPSADTAIKVEGGAAASDQILPEAEV-----------------------------------------------------------------------RLGQSGFMQRQFGAMLQPGVNKFSLRMFGSQKAVEREQERVKSAGFWIIHPYSDFRFYWDLTMLLLMVGNLIIIPVGITFFKDENTTPWIVFNVVSDTFFLIDLVLNFRTGIVVED-NTEIILDPQRIKMKYLKSWFVVDFISSIPVDYIFLIVETRIDSEVYKT-------ARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMT------------------------------YDLASAVVRIVNLIGMMLLLCHWDGCLQFLVPMLQDFPHDCWVSINGMVNNSWGKQYSYALFKAMSHMLCIGYGRQAPVGMSDVWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPPDTRQRIHDYYEHRYQGKMFDEESILGELSEPLREEIINFNCRKLVASMPLFANADPNFVTSMLTKLRFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTK-GNKETKLADGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVALDRLDRIGKKNSILLHKVQHDLNSGVFNYQENEIIQQIVRHDREMAHCAHRVQAAAS-ATPTPTP-----VIWTPLIQAPLQAAAATTSVAIALTHHPRLPAAIFRPPPGPGLGNLGAGQTPRHPRRLQSLIP-----SALGSASPASSPSQVDTPSSSSFHIQQLAGFSAPPGLSPLLPSSSSSPPPGACS--------------------------SPPAPTPSTST--AATTTG------FGHFHKALGGSLSSSDSPLLTP--------LQPGARSPQAAQPPPPLPGARGGLGLLEHFLPPPPSSRSPSSSPGQLGQPPGELSPGLAAGPPSTPETPPR-PERPSFMAGASGGASPVAFTPRGGLSPPGHSPGPP--RTFP-SAPPRASGSHGSLLLPPASSP--PPPQVPQRRGTPPLTPGRLTQDLKLISASQPALPQDGAQTLRRASPHSSGESMAAFSLYPRAGGGSG---SSGGLGPPGRPYGAIPGQHVTLPRKTSSGSLPPPLSLFGARAASSGGPPLT-AAPQREPGARSEPVRSKLPSNL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70507-1", "uniprot_id": "HCN4_MOUSE", "id": "O70507-1", "name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDKLPPSMRKRLYSLPQQVGAKAWIMDEEEDGEEEGAGGRQDPSRRSIRLRPLPSPSP------------------------------------------------SVAAGCSESRGAALGATESEGPGRSAGKSSTNGDCRRFRGSLASLGSRGGGSGGAGGGSSLGHLHDSAE-------------------ERRLIAAEGDASPGEDRTPPGLATEPERPATAAQPAASPPP----------------------------------------------------QQPPQPASASCEQPSADTAIKVEGGAAASDQILPEAEV-----------------------------------------------------------------------RLGQSGFMQRQFGAMLQPGVNKFSLRMFGSQKAVEREQERVKSAGFWIIHPYSDFRFYWDLTMLLLMVGNLIIIPVGITFFKDENTTPWIVFNVVSDTFFLIDLVLNFRTGIVVED-NTEIILDPQRIKMKYLKSWFVVDFISSIPVDYIFLIVETRIDSEVYKT-------ARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMT------------------------------YDLASAVVRIVNLIGMMLLLCHWDGCLQFLVPMLQDFPHDCWVSINGMVNNSWGKQYSYALFKAMSHMLCIGYGRQAPVGMSDVWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPPDTRQRIHDYYEHRYQGKMFDEESILGELSEPLREEIINFNCRKLVASMPLFANADPNFVTSMLTKLRFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTK-GNKETKLADGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVALDRLDRIGKKNSILLHKVQHDLNSGVFNYQENEIIQQIVRHDREMAHCAHRVQAAAS-ATPTPTP-----VIWTPLIQAPLQAAAATTSVAIALTHHPRLPAAIFRPPPGPGLGNLGAGQTPRHPRRLQSLIP-----SALGSASPASSPSQVDTPSSSSFHIQQLAGFSAPPGLSPLLPSSSSSPPPGACG--------------------------SPPAPTPSTSTAAAASTTG------FGHFHKALGGSLSSSDSPLLTP--------LQPGARSPQAAQPPPPLPGARGGLGLLEHFLPPPPSSRSPSSSPGQLGQPPGELSLGLAAGPSSTPETPPR-PERPSFMAGASGGASPVAFTPRGGLSPPGHSPGPP--RTFP-SAPPRASGSHGSLLLPPASSP--PPPQVPQRRGTPPLTPGRLTQDLKLISASQPALPQDGAQTLRRASPHSSGESVAAFSLYPRAGGGSG---SSGGLGPPGRPYGAIPGQHVTLPRKTSSGSLPPPLSLFGARAASSGGPPLTTAAPQREPGARSEPVRSKLPSNL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y3Q4-1", "uniprot_id": "HCN4_HUMAN", "id": "Q9Y3Q4-1", "name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDKLPPSMRKRLYSLPQQVGAKAWIMDEEEDAEEEGAGGRQDPSRRSIRLRPLPSPSP------------------------------------------------SAAAGGTESRSSALGAADSEGPARGAGKSSTNGDCRRFRGSLASLGSRGGGSGGTGSGSSHGHLHDSAE-------------------ERRLIA-EGDASPGEDRTPPGLAAEPERPGASAQPAASPPP---------------------------------------------------PQQPPQPASASCEQPSVDTAIKVEGGAAAGDQILPEAEV-----------------------------------------------------------------------RLGQAGFMQRQFGAMLQPGVNKFSLRMFGSQKAVEREQERVKSAGFWIIHPYSDFRFYWDLTMLLLMVGNLIIIPVGITFFKDENTTPWIVFNVVSDTFFLIDLVLNFRTGIVVED-NTEIILDPQRIKMKYLKSWFMVDFISSIPVDYIFLIVETRIDSEVYKT-------ARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMT------------------------------YDLASAVVRIVNLIGMMLLLCHWDGCLQFLVPMLQDFPDDCWVSINNMVNNSWGKQYSYALFKAMSHMLCIGYGRQAPVGMSDVWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPPDTRQRIHDYYEHRYQGKMFDEESILGELSEPLREEIINFNCRKLVASMPLFANADPNFVTSMLTKLRFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTK-GNKETKLADGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVALDRLDRIGKKNSILLHKVQHDLNSGVFNYQENEIIQQIVQHDREMAHCAHRVQAAAS-ATPTPTP-----VIWTPLIQAPLQAAAATTSVAIALTHHPRLPAAIFRPPPGSGLGNLGAGQTPRHLKRLQSLIP-----SALGSASPASSPSQVDTPSSSSFHIQQLAGFSAPAGLSPLLPSSSSSPPPGACG--------------------------SPSAPTPSAGVA-ATTIAG------FGHFHKALGGSLSSSDSPLLTP--------LQPGARSPQAAQPSPAPPGARGGLGLPEHFLPPPPSSRSPSSSPGQLGQPPGELSLGLATGPLSTPETPPRQPEPPSLVAGASGGASPVGFTPRGGLSPPGHSPGPP--RTFP-SAPPRASGSHGSLLLPPASSP--PPPQVPQRRGTPPLTPGRLTQDLKLISASQPALPQDGAQTLRRASPHSSGESMAAFPLFPRAGGGSGGSGSSGGLGPPGRPYGAIPGQHVTLPRKTSSGSLPPPLSLFGARATSSGGPPLT-AGPQREPGARPEPVRSKLPSNL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7TEJ3-1", "uniprot_id": "A0A8N7TEJ3_DANRE", "id": "A0A8N7TEJ3-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MHRVHSSMRKRLYSLPHQFGHKGAMNRDGEDSD-------KDTRRKSVKMKHFPSPSS------------------------------------------------TGSSKGVCEAKSGDAETDVGRPFR----TNVNGDCRRFRGSLSSLTSR------------HAAPDADLA-------------------EQRRLIGD--ASPEDD-GPSEQPGPGESPGAQGGRGD-------------------------------------------------------GAQQAPS-------EEQSTFVKLEG----IDQILPDDE------------------------------------------------------------------------RMYQAGFMHRQFGAMLQPGVNKFSLRMFGSEKAVEHEQERVKSAGFWIIHPYSDFRFYWDLIMLLLMVGNLIIIPVGITFFKDEHTPAWIVFNVVSDTFFLVDLVLNFRTGIVKED-STEIILDPQQIKVRYLRSWFAVDFLSSIPVDYIFLIVETRIDSDFYKT-------ARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMT------------------------------YDLASAMVRIVNLIGMMLLLCHWDGCLQFLVPMLQDFPSDCWVAKNKMVNDTWGQQYSYALFKAMSHMLCIGYGMYPPVGMTDVWLTILSMIVGATCYAMFVGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADMRQRIHDYYEHRYQGKMFDEESILGELNEPLREEIISFNCRKLVATMPLFANADPNFVTSMLTKLRFEVFQPGDYIIREGTVGKKMYFIQHGVLTVLTK-GSKETKISDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDHFNEVLEEYPMMRRAFETVALDRLDRIGKRNSVLQHKVQRDLNSGVLNYQENEIIQQIVQHDRDMAHCAHLMQTPPPPPHPAPTPSSHTPVIWAPLIQAPLQAAAATTSVAIALTRHPHLPHTLFR-PPVPRLGSL--KDQPGYFKRFPTALSGADTFGGSSSTS-SQFSSCIETPILDTLRAERSSTSTPPPSSSSLPTTITTTVTTTTSSITESSHYHHRPIISHGSKDFSVAQLHSQPQLSQASFSSIAASLPGFFQQGAAGGEAVHLAVPPASTLTPLIAHSVSPILTQLHATHSNPQPTKPIQDLNKAGRTAPQS--PVTESPVHSKSILEQVQSPTSVQSQHPQIGIQPDVLSQLAQEPSALASLAQYGSGNASPCSTP--SAWSPTCQSPTAEKMRMSAHSQPSSISGSQTSLLTPQTLFP--PPPQPRERGGS---LVDLPSQDLSTLSMSLPIPGLAEKSRAVGRGPQPPDLSHHRGSTSGYSPLPSP--------PPLVNPFSSIPG-HVVLSRQTSKLSI--------TQTGSSGGSPAHGSSDRSTPGTPS--LHPKLPSNL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8N7UQR8-1", "uniprot_id": "A0A8N7UQR8_DANRE", "id": "A0A8N7UQR8-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDRLHSSMRKRLYSLPQHIGQKASIMGDAEDSD-------KDTRRKSIRMKPLPTSGE------------------------------------------------IKS------GESAIMETDIGRPVK----TSSNGDCRRFRGSLSSITSR------------HVH-DSDVA-------------------EERRLITDGEVTPSEE-SPPGAAGGGAEPGAQSGGGG-------------------------------------------------------GEEAAGSSQHQGIPDQQAGFIKLEG----IEQILPDDE------------------------------------------------------------------------RYYQAGFMHRQFGAMLQPGVNKFSLRMFGSEKAVEREQERVKSAGFWIIHPYSDFRFYWDLTMLLLMVGNLIIIPVGITFFKDEHTPPWIVFNVVSDTFFLMDLVLNFRTGIVKED-NAEIILDPQQIKIKYLRSWFVVDFISSIPVDYIFLIVETRIDSDFYKT-------ARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMT------------------------------YDLASAMVRIVNLIGMMLLLCHWDGCLQFLVPMLQDFPADCWVAKNKMVNDTWGQQYSYALFKAMSHMLCIGYGMYPPVGMTDVWLTILSMIVGATCYAMFVGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADMRQRIHDYYEHRYQGKMFDEESILGELNEPLREEIINFNCRKLVASMPLFANADPNFVTSMLTKLRFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTK-GNKETKLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVALDRLDRIGKKNSILQHKVQHDLNSGVLNYQESEIIQQIVQHDRDMAHCANLLQSPSPPAPPSPTP-----VIWAPLIQAPLQAAAATTSVAIALTHHPHLPATLFR-PPVSLLGSR--NEPPSRLKRFQTVAPRTGSTTDSPSTSPSKLHSGVDTPLLASLHTQHSSVTITPSATTNQPVSFRSFSSPSAS------------------PTLSTAQLHPQPRQKQPSTPPLSARLQ------AAGAHPPGILTTASSNTSALSAG-----LSTHSPTHSYPPPKHPQTGSLQFASGGGKSGLTLFHSPPPGSPISIHSQAPESSTSSQ----TQPSFSSYLALERSALASIAQYGSANASPSYTP--LALSPTVQSPVTG--RTFQYSDPSSAAGSHTSLLLPQSSCPGQLPGHHSSGTDS---PLGRFYEDLNILSSSHPSLGVEGAG---------------QSSPGYLSPYLSP--------TLTPKPCSSVSG-HMSSPVQTSPGPR--------GQALSVGTSPALSLPRTSDGDLEP--LRSKLPSNL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z9N7-1", "uniprot_id": "A1Z9N7_DROME", "id": "A1Z9N7-1", "name": "", "aln": "MHVKHTQRRVSGPGAFGTFTNDQRASRDNLCPDNQQQQQQRHSHSHQHLVRQSLVSLSNGQPAASAAPDSVSLLRAGDDQQQHPQQPHLQQQQQQQQHLQQQQQRHRSSSSRLSTSGISKQNSSDSRSGLRILDSSHSPVSCGTQSVSSTGGQSALYDACHEYSRSLSAAAAEGAASLLKSHYSDQQLAQTEPDPEPDPERDRDRDRDRDRDRERERRHLTNLNLNLSSEYDYSGSDKQQLVNETYIFKCIANSPSFLRTNKIKEQSKKLRNLSLKTRTAKKKGQIISKSNAVSDNSLHPGDKYLNLYLVEKKHSLQPQVASTSSSINTTHPQASSAPASSSSTCTKAPQLPALSAVAARQQQLLLNGSLKGKGQSQSQGQSRQTLPGHRASVRSESGSGSSHTIPATGKSPPVPHSLAAKISSSASGSKNCNLLSASSNSCHKLNAHAQGSGAGSGSGSGSGSGPPGHSHYAAASPKSSVSSNGHLNKYCLTDLTRRKAEFNRQLSAPTDYTHHSSSNGSQQEGSSEANEGHEPVGESTITVASAGVSYPHPYSYPYHYAHHASSATAPANLKASLQLHSFGSHHPCPYPARPTSTSCTNSFNRRHIRRHKGKLGDRLLSGDSEESVRCSYCSVLNVNDNDLRISFENTCTDSLVTAFDDEALLICDQGTEMVHFDDVSLYGTPKEEPMPNIPIVSEKVSANFLKSQLQSWFQPTDNRLAMKLFGSRKALVKERIRQKTSGHWVIHPCSSFRFYWDLCMLLLLVANLIILPVAISFFNDDLSTRWIAFNCLSDTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFFLDLISSIPLDYIFLIFNQIMKLQDFSDSFQILHAGRALRILRLAKLLSLVRLLRLSRLVRYVSQWEEVYILQNLQKKSADRRGRMNRKDKDGLTKSNLILKFLNMASVFMRIFNLICMMLLIGHWSGCLQFLVPMLQGFPSNSWVSINELQESYWLEQYSWALFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQSLDSSRRQYREKVKQVEEYMAYRKLPRDMRQRITEYFEHRYQGKFFDEELILGELSEKLREDVINYNCRSLVASVPFFANADSNFVSDVVTKLKYEVFQPGDIIIKEGTIGTKMYFIQEGVVDIVMANGEVATSLSDGSYFGEICLLTNARRVASVRAETYCNLFSLSVDHFNCVLDQYPLMRKTMETVAAERLNKIGKNPNIMHQKDEQLSNP-----ESNTITAVVNALAAEADDCKDDD---------------------MDLKENLLHGSESSIAEPVQTIREG------LPRPRSGEFRALFEGNTP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : :: :** :.. .. . ... :: :: :.: . :. :. . . : ...*:::.. . : .* : :. : . .: . . :: . : : * . .:.*:: *: : :** *::::::***.**: :*: * *::*.*:*** *.******* ****:*.****:**.*:**:*: :. **.** :***:**:*:*:******: :* ::****: * :**::** :*::****:******.: :. : :. .*****:*::*:***:********:**: ****:: : ::**..:**.*** ****: **.***********.** :.**: * : :. * :***:*************** .* .::*:***:**** ******:*:**** ************:** ****:**:::*** * **** :*:*******:**** *****.* ***::*.:***.***::*:*****.***:.::***::******* **:***:*.******.**: :: *. *.::************..**.*****:***.*:*****:** **::**:**:::**** :**::***. .:: :* :: *. :.. * : : .* . * : *:.: :: : .: :. : * : : * ", "identical_positions": 320, "similar_positions": 229, "identity": "17.87%" }, { "cls_id": "homologset.agr.MGI:1298210", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JKA9-1", "uniprot_id": "HCN2_RAT", "id": "Q9JKA9-1", "name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDARGGGG------RPGDSPGATP-----APGPPPPPPPPAP------------------PQPQPPPAPPPNP--TTPSHP--------ESADEPGPRSRL------------CSRDSSC----TPGAA---KGGANGECGRGEPQCS---PEGPARGP------------------------------------KVSFSCRGAASGPA----AAEEAG--------------------------------------------------------------------------------------SEE----------------------------------------------------AGPAGEPRG------------SQASFLQRQFGALLQPGVNKFSLRMFGSQKAVEREQERVKSAGAWIIHPYSDFRFYWDFTMLLFMVGNLIIIPVGITFFKDETTAPWIVFNVVSDTFFLMDLVLNFRTGIVIEDN-TEIILDPEKIKKKYLRTWFVVDFVSSIPVDYIFLIVEKGIDS-------EVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMT------------------------------YDLASAVMRICNLISMMLLLCHWDGCLQFLVPMLQDFPSDCWVSINNMVNHSWSELYSFALFKAMSHMLCIGYGRQAPESMTDIWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADFRQKIHDYYEHRYQGKMFDEDSILGELNGPLREEIVNFNCRKLVASMPLFANADPNFVTAMLTKLKFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTK-GNKEMKLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVAIDRLDRIGKKNSILLHKVQHDLSSGVFNNQENAIIQEIVKYDREMVQQAELG--QR-----------VGLFPPPPPP-QVTSAIATLQQAVAMSFCPQVARPLVGPLALGSPRLVR-------RAPPGPLPPAASPGPP-AASPPAAPSSPRAP----RTSPYG-VPGS---------PATRVGPALPARRLSRASRPLSASQPSLP---HGAPAPSPAASARPASSST-----------------PRLGPAPTTRTAAPSPDRRDSASPGAASGLDPLDSA-----------RSRLSSNL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88703-1", "uniprot_id": "HCN2_MOUSE", "id": "O88703-1", "name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDARGGGG------RPGDSPGTTP-----APGPPPPPPPPAP------------------PQPQPPPAPPPNP--TTPSHP--------ESADEPGPRARL------------CSRDSAC----TPGAA---KGGANGECGRGEPQCS---PEGPARGP------------------------------------KVSFSCRGAASGPS----AAEEAG--------------------------------------------------------------------------------------SEE----------------------------------------------------AGPAGEPRG------------SQASFLQRQFGALLQPGVNKFSLRMFGSQKAVEREQERVKSAGAWIIHPYSDFRFYWDFTMLLFMVGNLIIIPVGITFFKDETTAPWIVFNVVSDTFFLMDLVLNFRTGIVIEDN-TEIILDPEKIKKKYLRTWFVVDFVSSIPVDYIFLIVEKGIDS-------EVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMT------------------------------YDLASAVMRICNLISMMLLLCHWDGCLQFLVPMLQDFPSDCWVSINNMVNHSWSELYSFALFKAMSHMLCIGYGRQAPESMTDIWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADFRQKIHDYYEHRYQGKMFDEDSILGELNGPLREEIVNFNCRKLVASMPLFANADPNFVTAMLTKLKFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTK-GNKEMKLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVAIDRLDRIGKKNSILLHKVQHDLSSGVFNNQENAIIQEIVKYDREMVQQAELG--QR-----------VGLFPPPPPP-QVTSAIATLQQAVAMSFCPQVARPLVGPLALGSPRLVR-------RAPPGPLPPAASPGPP-AASPPAAPSSPRAP----RTSPYG-VPGS---------PATRVGPALPARRLSRASRPLSASQPSLP---HGVPAPSPAASARPASSST-----------------PRLGPAPTARTAAPSPDRRDSASPGAASGLDPLDSA-----------RSRLSSNL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UL51-1", "uniprot_id": "HCN2_HUMAN", "id": "Q9UL51-1", "name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDARGGGG------RPGESPGATP-----APGPPPPPPPAPPQQ---------------QPPPPPPPAPPPGPGPAPPQHPPRAEALPPEAADEGGPRGRL------------RSRDSSCGRPGTPGAASTAKGSPNGECGRGEPQCSPAGPEGPARGP------------------------------------KVSFSCRGAASGPAPGPGPAEEAG--------------------------------------------------------------------------------------SEE----------------------------------------------------AGPAGEPRG------------SQASFMQRQFGALLQPGVNKFSLRMFGSQKAVEREQERVKSAGAWIIHPYSDFRFYWDFTMLLFMVGNLIIIPVGITFFKDETTAPWIVFNVVSDTFFLMDLVLNFRTGIVIEDN-TEIILDPEKIKKKYLRTWFVVDFVSSIPVDYIFLIVEKGIDS-------EVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMT------------------------------YDLASAVMRICNLISMMLLLCHWDGCLQFLVPMLQDFPRNCWVSINGMVNHSWSELYSFALFKAMSHMLCIGYGRQAPESMTDIWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADFRQKIHDYYEHRYQGKMFDEDSILGELNGPLREEIVNFNCRKLVASMPLFANADPNFVTAMLTKLKFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTK-GNKEMKLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVAIDRLDRIGKKNSILLHKVQHDLNSGVFNNQENAIIQEIVKYDREMVQQAELG--QR-----------VGLFPPPPPPPQVTSAIATLQQAAAMSFCPQVARPLVGPLALGSPRLVR-------RPPPGPAPAAASPGPPPPASPPGAPASPRAP----RTSPYGGLPAA---------PLA--GPALPARRLSRASRPLSASQPSLP---HGAPG--PAASTRPASSST-----------------PRLGPTPAARAAAPSPDRRDSASPGAAGGLDPQDSA-----------RSRLSSNL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7T6V3-1", "uniprot_id": "A0A8N7T6V3_DANRE", "id": "A0A8N7T6V3-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDEAEDGDEDHKETRRGDILDSSSKMKTVAPGGGAASSRISNNKDFASC----------GRSTESAALLGHGDASRSGAHS--------DGEDATGMRCVINGD---------CRRDDSVCSVLSKLEKQTGGGFPASACHSSTSSMDGSVTPAAAAAPP-----------------------------ADKKDSRVSFSSAAPAHGPS----PSNPAGNSVSFSK-------------------------------------------------------------------------------SEDGQ-------------------------------------------------ITAEDGEARD------------NQT-YMQRQFSAMLQPGVNKFSLRMFGSQKAVEKEQERVKSAGNWIIHPYSDFRFYWDFTMLMFMVGNLIIIPVGITFFKEETTTPWIIFNVVSDTFFLMDLVLNFRTGIVYEDN-TEIILDPEKIKKKYLKTWFVVDFVSSIPVDYIFLIVEKGIDS-------EVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMT------------------------------YDLASAVMRIINLIGMMLLLCHWDGCLQFLVPMLQDFPSDCWVSLNKMVNDSWSELYSFALFKAMSHMLCIGYGRQAPESMSDIWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADFRQKIHDYYEHRYQGKMFDEESILEELNEPLREEIVNFNCRKLVASMPLFANADPNFVTAMLTKLRFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTK-GNIGMKLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVAIDRLDRIGKKNSILMHKVQHDLNSGVFNNRENEMIQEIVKYDREMVKLVKQGDMQRPRAMSMTPSTHGSMFGPSSQP-STSSAIATLQQAVAMSFCPQMGNPLMGSGSVQSPRMVRRFQVVQTQTPPGSQYSTLARASALASTPVHSPLATTARTFQYGSSPPGAPSGSQLSLVQQLVPSPTHRPAVHRSTLTQDARALSASQPSLRPDMIQPVAPSPPQSTRVSSTSIGPPQNLPGPTGLRGSIPPRMALTHQMSVGAFPPASLPQMRPSLDSGLPKKDSISSLPETEQHHIRSRLSSNL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z9N7-1", "uniprot_id": "A1Z9N7_DROME", "id": "A1Z9N7-1", "name": "", "aln": "MHVKHTQRRVSGPGAFGTFTNDQRASRDNLCPDNQQQQQQRHSHSHQHLVRQSLVSLSNGQPAASAAPDSVSLLRAGDDQQQHPQQPHLQQQQQQQQHLQQQQQRHRSSSSRLSTSGISKQNSSDSRSGLRILDSSHSPVSCGTQSVSSTGGQSALYDACHEYSRSLSAAAAEGAASLLKSHYSDQQLAQTEPDPEPDPERDRDRDRDRDRDRERERRHLTNLNLNLSSEYDYSGSDKQQLVNETYIFKCIANSPSFLRTNKIKEQSKKLRNLSLKTRTAKKKGQIISKSNAVSDNSLHPGDKYLNLYLVEKKHSLQPQVASTSSSINTTHPQASSAPASSSSTCTKAPQLPALSAVAARQQQLLLNGSLKGKGQSQSQGQSRQTLPGHRASVRSESGSGSSHTIPATGKSPPVPHSLAAKISSSASGSKNCNLLSASSNSCHKLNAHAQGSGAGSGSGSGSGSGPPGHSHYAAASPKSSVSSNGHLNKYCLTDLTRRKAEFNRQLSAPTDYTHHSSSNGSQQEGSSEANEGHEPVGESTITVASAGVSYPHPYSYPYHYAHHASSATAPANLKASLQLHSFGSHHPCPYPARPTSTSCTNSFNRRHIRRHKGKLGDRLLSGDSEESVRCSYCSVLNVNDNDLRISFENTCTDSLVTAFDDEALLICDQGTEMVHFDDVSLYGTPKEEPMPNIPIVSEKVSANFLKSQLQSWFQPTDNRLAMKLFGSRKALVKERIRQKTSGHWVIHPCSSFRFYWDLCMLLLLVANLIILPVAISFFNDDLSTRWIAFNCLSDTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFFLDLISSIPLDYIFLIFNQIMKLQDFSDSFQILHAGRALRILRLAKLLSLVRLLRLSRLVRYVSQWEEVYILQNLQKKSADRRGRMNRKDKDGLTKSNLILKFLNMASVFMRIFNLICMMLLIGHWSGCLQFLVPMLQGFPSNSWVSINELQESYWLEQYSWALFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQSLDSSRRQYREKVKQVEEYMAYRKLPRDMRQRITEYFEHRYQGKFFDEELILGELSEKLREDVINYNCRSLVASVPFFANADSNFVSDVVTKLKYEVFQPGDIIIKEGTIGTKMYFIQEGVVDIVMANGEVATSLSDGSYFGEICLLTNARRVASVRAETYCNLFSLSVDHFNCVLDQYPLMRKTMETVAAERLNKIGK-NPNIMHQKDEQLS-----NPESNTITAVVN-------------------------------ALAAEADDCKDDDMDLKENLLHGSESSIAEPVQTIREG-----------------------------------------------------------------------------LPRPRSGEFRALFEGNTP-------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ... : .. ::. ** . .. . . . . . . : .: . . . . . . . .* .* : * * . *.: : .* **: .. * .: .: ::: *: : :** *::::::***:**: :*: * *::* *:*** *.******: **:::*.****:**.*:**::: :: ** ** :***:**:*:*:******: :** ::****: * *:**:***.:*::****:******.:: :. :: ::.*****:*::*:***:********:**: ****:: : ::**..*** *** ****: **.***********.** :.***:* : : * * **:**************** .*:*::*:******** ******:*:**** ************:** ****:**:::*** *:**:* :*:*******:***: ** **. ***:::*:***.****:*:*****.***: ::***::******* **:*****.******.***.:: *: .**************..**.*****:***.*:*****:** **::**:**:::**** :**::*** *. ::*: :.:*. * *. * :*: .. . . .. *:: . ..:..*: : . :... * ", "identical_positions": 331, "similar_positions": 214, "identity": "21.52%" }, { "cls_id": "homologset.agr.MGI:1298211", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JKA8-1", "uniprot_id": "HCN3_RAT", "id": "Q9JKA8-1", "name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEEEARPAVGDGE-----------------------------------------------------------------AATP-ARETPP-------------------------------------------------------------------------------------------------------------AAPAQARAASG-------------------------------------------------------------------------------------GVPESAPEPK-------------RRQLGTLLQPTVNKFSLRVFGSHKAVEIEQERVKSAGAWIIHPYSDFRFYWDLIMLLLMVGNLIVLPVGITFFKEENSPPWIVFNVLSDTFFLLDLVLNFRTGIVVEEGAE-ILLAPRAIRTRYLRTWFLVDLISSIPVDYIFLVVELEPRLD-----AEVYKTARALRIVRFTKILSLLRLLRLSRLIRYMHQWEEIFHMT------------------------------YDLASAVVRIFNLIGMMLLLCHWDGCLQFLVPMLQDFPSDCWVSMNRMVNHSWGRQYSHALFKAMSHMLCIGYGQQAPVGMPDVWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADTRQRIHEYYEHRYQGKMFDEESILGELSEPLREEIINFTCRGLVAHMPLFAHADPSFVTAVLTKLRFEVFQPGDLVVREGSVGRKMYFIQHGLLSVLAR-GARDTRLTDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDHFNAVLEEFPMMRRAFETVAMDRLRRIGKKNSILQRKRSEPSPGSSSGGVMEQHLVQHDRDMARGIRGLAPGTGARLSGKPVLWEPLVHAPLQAAAVTSNVAIALTHQRGPLPLSPDSPATLLARSARRSAGSPASPLVPVRAGPLLARGPWASTSRLPAPPARTLHASLSRTGRSQVSLLGPPPGGGGRRLGPRGRPLSASQPSLPQRATGDGSPRRKGSGSERLPPSGLLAKPPGTVQPSRSSVPEPVTPRGPQISANM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88705-1", "uniprot_id": "HCN3_MOUSE", "id": "O88705-1", "name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEEEARPAAGAGE-----------------------------------------------------------------AATP-ARETPP-------------------------------------------------------------------------------------------------------------AAPAQARAASG-------------------------------------------------------------------------------------GVPESAPEPK-------------RRQLGTLLQPTVNKFSLRVFGSHKAVEIEQERVKSAGAWIIHPYSDFRFYWDLIMLLLMVGNLIVLPVGITFFKEENSPPWIVFNVLSDTFFLLDLVLNFRTGIVVEEGAE-ILLAPRAIRTRYLRTWFLVDLISSIPVDYIFLVVELEPRLD-----AEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMT------------------------------YDLASAVVRIFNLIGMMLLLCHWDGCLQFLVPMLQDFPSDCWVSMNRMVNHSWGRQYSHALFKAMSHMLCIGYGQQAPVGMPDVWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADTRQRIHEYYEHRYQGKMFDEESILGELSEPLREEIINFTCRGLVAHMPLFAHADPSFVTAVLTKLRFEVFQPGDLVVREGSVGRKMYFIQHGLLSVLAR-GARDTRLTDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDHFNAVLEEFPMMRRAFETVAMDRLRRIGKKNSILQRKRSEPSPGSS-GGVMEQHLVQHDRDMARGVRGLAPGTGARLSGKPVLWEPLVHAPLQAAAVTSNVAIALTHQRGPLPLSPDSPATLLARSARRSAGSPASPLVPVRAGPLLARGPWASTSRLPAPPARTLHASLSRTGRSQVSLLGPPPGGGARRLGPRGRPLSASQPSLPQRATGDGSPRRKGSGSERLPPSGLLAKPPGTVQPPRSSVPEPVTPRGPQISANM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P1Z3-1", "uniprot_id": "HCN3_HUMAN", "id": "Q9P1Z3-1", "name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEAEQRPAAGASE-----------------------------------------------------------------GATPGLEAVPP-------------------------------------------------------------------------------------------------------------VAPPPATAASG-------------------------------------------------------------------------------------PIPKSGPEPK-------------RRHLGTLLQPTVNKFSLRVFGSHKAVEIEQERVKSAGAWIIHPYSDFRFYWDLIMLLLMVGNLIVLPVGITFFKEENSPPWIVFNVLSDTFFLLDLVLNFRTGIVVEEGAE-ILLAPRAIRTRYLRTWFLVDLISSIPVDYIFLVVELEPRLD-----AEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMT------------------------------YDLASAVVRIFNLIGMMLLLCHWDGCLQFLVPMLQDFPPDCWVSINHMVNHSWGRQYSHALFKAMSHMLCIGYGQQAPVGMPDVWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADTRQRIHEYYEHRYQGKMFDEESILGELSEPLREEIINFTCRGLVAHMPLFAHADPSFVTAVLTKLRFEVFQPGDLVVREGSVGRKMYFIQHGLLSVLAR-GARDTRLTDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDHFNAVLEEFPMMRRAFETVAMDRLLRIGKKNSILQRKRSEPSPGSS-GGIMEQHLVQHDRDMARGVRGRAPSTGAQLSGKPVLWEPLVHAPLQAAAVTSNVAIALTHQRGPLPLSPDSPATLLARSAWRSAGSPASPLVPVRAG------PWASTSRLPAPPARTLHASLSRAGRSQVSLLGPPPGGGGRRLGPRGRPLSASQPSLPQRATGDGSPGRKGSGSERLPPSGLLAKPPRTAQPPRPPVPEPATPRGLQLSANM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F6NQL8-1", "uniprot_id": "F6NQL8_DANRE", "id": "F6NQL8-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDGDGQPPASNGDSKLRSRGGFSLTGWRSSSKTLLRGEAEDVSRRLLSIVNHNQERSDSGASPTSKSLEVTAGLDGTTATTTTVTAATP-------------------------------------------------------------------------------------------------------------PLPHKAMPESS-------------------------------------------------------------------------------------GAPVASEAEDGPFVDQST---FLQRQFSSMLQPGVNKFSLRMFGSAKGVAAEQDRVKSFGVWIIHPYSDFRFYWDLVMLCLMMGNLVILPWGITFFEDQNTLPWITFNVASDTLFLADLVFNFRTGIMEGDNSE-IILDPQIISRRYLRGWFLVDFISSIPVDYIFLIVDIESRLES----AEVYRTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMT------------------------------YDLASAVVRIVNLIGMMLLLCHWDGCMQFMVPMLQDFPSTCWVSKNNMVNSTWDVQYSYALFMAMSHMLCIGYGAQAPEGPTDVWLTMISMIIGATCYAMFLGNATNLVQSLDASHRQYQEKYKQVEQYMSFHKLPADMRQRIHDYYEHRFQGKMFDEENILEELSDPLKEEIVNYNCRGLVANMPLFANADPHFVTVLLSKLRFEVFQPGDVIIREGTLGRKMYFIQHGCVSVITS-DNKEKKLNDGCYFGEICLLTRGRRTASVRADTYCRLYSLSVDSFNEVLEENPLMRRAFENVAVNRLGRESNGYEHSYKN------------------MEDDGD--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z9N7-1", "uniprot_id": "A1Z9N7_DROME", "id": "A1Z9N7-1", "name": "", "aln": "MHVKHTQRRVSGPGAFGTFTNDQRASRDNLCPDNQQQQQQRHSHSHQHLVRQSLVSLSNGQPAASAAPDSVSLLRAGDDQQQHPQQPHLQQQQQQQQHLQQQQQRHRSSSSRLSTSGISKQNSSDSRSGLRILDSSHSPVSCGTQSVSSTGGQSALYDACHEYSRSLSAAAAEGAASLLKSHYSDQQLAQTEPDPEPDPERDRDRDRDRDRDRERERRHLTNLNLNLSSEYDYSGSDKQQLVNETYIFKCIANSPSFLRTNKIKEQSKKLRNLSLKTRTAKKKGQIISKSNAVSDNSLHPGDKYLNLYLVEKKHSLQPQVASTSSSINTTHPQASSAPASSSSTCTKAPQLPALSAVAARQQQLLLNGSLKGKGQSQSQGQSRQTLPGHRASVRSESGSGSSHTIPATGKSPPVPHSLAAKISSSASGSKNCNLLSASSNSCHKLNAHAQGSGAGSGSGSGSGSGPPGHSHYAAASPKSSVSSNGHLNKYCLTDLTRRKAEFNRQLSAPTDYTHHSSSNGSQQEGSSEANEGHEPVGESTITVASAGVSYPHPYSYPYHYAHHASSATAPANLKASLQLHSFGSHHPCPYPARPTSTSCTNSFNRRHIRRHKGKLGDRLLSGDSEESVRCSYCSVLNVNDNDLRISFENTCTDSLVTAFDDEALLICDQGTEMVHFDDVSLYGTPKEEPMPNIPIVSEKVSANFLKSQLQSWFQPTDNRLAMKLFGSRKALVKERIRQKTSGHWVIHPCSSFRFYWDLCMLLLLVANLIILPVAISFFNDDLSTRWIAFNCLSDTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFFLDLISSIPLDYIFLIFNQIMKLQDFSDSFQILHAGRALRILRLAKLLSLVRLLRLSRLVRYVSQWEEVYILQNLQKKSADRRGRMNRKDKDGLTKSNLILKFLNMASVFMRIFNLICMMLLIGHWSGCLQFLVPMLQGFPSNSWVSINELQESYWLEQYSWALFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQSLDSSRRQYREKVKQVEEYMAYRKLPRDMRQRITEYFEHRYQGKFFDEELILGELSEKLREDVINYNCRSLVASVPFFANADSNFVSDVVTKLKYEVFQPGDIIIKEGTIGTKMYFIQEGVVDIVMANGEVATSLSDGSYFGEICLLTNARRVASVRAETYCNLFSLSVDHFNCVLDQYPLMRKTMETVAAERLNKIGKNPNIMHQKD-------------EQLSNPESNTITAVVNALAAEADDCKDDDMDLKENLLHG---------------------------------------SESSIAEPVQTIREG-------------LPRP----------RSGEFRALFEGNTP----------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :. . .. . ..* * * . * * . : :: : :** *::::::*** *.: *: * *: * *:*** *.******* ** *::.**::** .*:**::: : **.** ***:** *:*.******: :.:* ::* *: * :*** **::*:*****:*****:.: :*: :: ::.*****:*::*:***:********:**: ****:: : ::**..:**.*** ****: **.**:**:*****.**. .*** *.: : * *** *** *********** .* . .*:****:*** ******:*:*:** *:****:*:***:** ****:**:::*** * **** :*:***:***:**** ** ***: *:*:::*:.**.*** :*:**:**. **: :::**::*******::::**::* ******.* :.:: . . *.**.*********..**.*****:***.*:***** ** **:: *:**:::*.** :** : .: . :: .. ", "identical_positions": 280, "similar_positions": 166, "identity": "18.94%" }, { "cls_id": "homologset.agr.MGI:1298216", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35486-1", "uniprot_id": "CRYGS_MOUSE", "id": "O35486-1", "name": "Gamma-crystallin S", "aln": "MSKTGGKISFYEDRNFQGRRYDCDCDCADFRSYLSRCNSIRVEGGTWAVYERPNFSGHMYILPQGEYPEYQRWMGLNDRLGSCRAVHLSSGGQAKIQVFEKGDFNGQMYETTEDCPSIMEQFHLREIHSCKVVEGTWIFYELPNYRGRQYLLDKKEYRKPVDWGAASPAIQSFRRIVE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0C5E9-1", "uniprot_id": "CRYGS_RAT", "id": "P0C5E9-1", "name": "Gamma-crystallin S", "aln": "MSKTGAKISFYEDRNFQGRRYDCDCDCVDFRSYLSRCNSIRVEGGTWAVYERPNFSGHMYILPQGEYPEYQRWMGLNDRLGSCRAVHLSSGGQYKIQIFEKGDFSGQMYETTEDCPSTMERFHLREIHSCKVLEGTWIFYELPSYHGRQYLLDKKEYRKPVDWGAASPAVQSFRRIVE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P22914-1", "uniprot_id": "CRYGS_HUMAN", "id": "P22914-1", "name": "Gamma-crystallin S", "aln": "MSKTGTKITFYEDKNFQGRRYDCDCDCADFHTYLSRCNSIKVEGGTWAVYERPNFAGYMYILPQGEYPEYQRWMGLNDRLSSCRAVHLPSGGQYKIQIFEKGDFSGQMYETTEDCPSIMEQFHMREIHSCKVLEGVWIFYELPNYRGRQYLLDKKEYRKPIDWGAASPAVQSFRRIVE", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***** **:****:*************.**::********:**************:*:**********************.*******.**** ***:******.************ **:**:********:**.*******.*:**************:********:********", "identical_positions": 155, "similar_positions": 20, "identity": "87.08%" }, { "cls_id": "homologset.agr.MGI:1298217", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O89098-1", "uniprot_id": "CYTF_MOUSE", "id": "O89098-1", "name": "Cystatin-F", "aln": "----MWLA-ILLALCCLTSDTHGAR-------------------------------PPDFCSKDLISSVKPGFPKTIETNNPGVLKAARHSVEKFNNCTNDIFLFKESHVSKALVQVVKGLKYMLEVKIGRTTCRKTMHHQLDNCDFQTNPALKRTLYCYSEVWVIPWLHSFEVPVLLCQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6ADY1-1", "uniprot_id": "A0A8I6ADY1_RAT", "id": "A0A8I6ADY1-1", "name": "", "aln": "MHTAMWLA-MLLALCCLTSDAHGAYTSGWVWSLGGSGKEYRRDAKDMESRFTASQVPRNFCSKDLNSGVEPGFPKTIKTNNPGVLKAARHSVEKFNNCTNDIFLFKESHVSKALVQVVKGLKYMLQVEIGRTTCRKTMHRQLDNCDFQTSPALKRTLHCYSEVWVIPWLHSFEVPVLRCH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O76096-1", "uniprot_id": "CYTF_HUMAN", "id": "O76096-1", "name": "Cystatin-F", "aln": "----MRAAGTLLAFCCLVLSTTGGP-------------------------------SPDTCSQDLNSRVKPGFPKTIKTNDPGVLQAARYSVEKFNNCTNDMFLFKESRITRALVQIVKGLKYMLEVEIGRTTCKKNQHLRLDDCDFQTNHTLKQTLSCYSEVWVVPWLQHFEVPVLRCH", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * ***:***. .: *. . : **:** * *:*******:**:****:***:***********:******::::****:********:*:******:*. * :**:*****. :**:** *******:***: ****** *:", "identical_positions": 97, "similar_positions": 31, "identity": "53.89%" }, { "cls_id": "homologset.agr.MGI:1298218", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K0H3-1", "uniprot_id": "A0A0G2K0H3_RAT", "id": "A0A0G2K0H3-1", "name": "Low-density lipoprotein receptor-related protein", "aln": "------------------------------------------------------------------MGAVLRSLLACSFCVLLRAAPLLLYANRRDLRLVDATN--GKENATIVVGGLEDAAAVDFVFGHGLIYWSDVSEEAIKRTEFNK-------TESVQNVVVSGLLSPDGLACDWLGEKLYWTDSETNRIEVSNLDGSLRKVLFWQELDQPRAIALDPSSGFMYWTDWGEVPKIERAGMDGS--SRFVIINTEIYWPNGLTLDYEERKLYWADAKLNFIHKSNLDGTNRQAVVKGSLPHPFALTLFEDTLYWTDWNTHSILACNKYTGEGLREIHSNIFSPMDIHAFSQQRQPNATNPCGIDNGGCSHLCLMSPVKPFYQCACPTGVKLLESGKTCKDGATELLLLARRTDLRRISLDTPDFTDIVLQLEDIRHAIAIDYDPVEGYVYWTDDEVRAIRRSFIDGSGSQFVVTAQIAHPDGIAVDWVARNLYWTDTGTDRIEVTRLNGTMRKILISEDLEEPRAIVLDPMAGYMYWTDWG-EIPKIERAALDGSDRVVLVNTSLGWPNGLALDYDEGTIYWGDAKTDKIEVMNTDGTGRRVLVEDKIPHIFGFTLLGDYVYWTDWQRRSIERVHKRS-AEREVIIDQLPDLMGLKATSVHRVIGSNPCAEENGGCSHLCLYRPQGLRCACPIGFELISDMKTCIVPEAFLLFSRRADIRRISLETN---NNNVAIPLTGVKEASALDFDVTDNRIYWTDISLKTISRAFMNGSALEHVVEFGLDYPEGMAVDWLGKNLYWADTGTNRIEVSKLDGQHRQVLVWKDLDSPRALALDPAEGFMYWTEWGGKPKIDRAAMDGSERTTLVPNVGRANGLTIDYAKRRLYWTDLDT-NLIESSNMLGLNREVIA-DDLPHPFGLTQYQDYIYWTDWSRRSIERANKTSGQNRTIIQGHLDYVMDILVFHSSRQAGWNECASSNGHCSHLCLAVPVG-GFVCGCPAHYSLNADNRTCSAPTTFLLFSQKSAINRMVIDEQQSPDIILPIHSLRNVRAIDYDPLDKQLYWIDSRQNMIRKAQEDGGQGFTVVVSSVPNQNLEIQPYDLSIDIYSRYIYWTCEATNVIDVTRLDGRSVGVVLKGEQDRPRAIVVNPEKGYMYFTNLQERSPKIERAALDGTEREVLFFSGLSKPVALALDSKLSRLFWADSDLRRIESSDLSGANRIVLEDSNILQPVGLTVFENWLYWIDKQQQMIEKIDMTGREGRTKVQARIAQLSDIHAVKELNLQEYRQHPCAQDNGGCSHICLVKGDGTTR----CSCPMHLVLLQDELSCGEPPTCSPQQFTCFT-------GDIDCIPVAWRCDGFTECEDHSDELNCPVCSESQFQCASGQCIDGALRCNGDANCQDKSDEKNCEVLCLIDQFRC-ANGQCVGKHKKCDHNVDCSDRSDELDCYPTEEPAPQATNTVGSVIGVIVTIFVSGTIYFICQRMLCPRMKGDGETMTNDYVVHGPASVPLGYVPHPSSLSGSLPGMSRGKSMISSLSIMGGSSGPPYDRAHVTGASSSSSSSTKGTYFPAILNPPPSPATERSHYTMEFGYSSNSPSTHR--SYRPYSYRHFAPPTTPCSTDVCD---SDYAP-SRRMTSVATAKGYTS-------DLNYDSEPVPPPPTPRSQYLSAEENY--ESCPPSPYTERSYSHHLYPPPPSPCTDSS----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88572-1", "uniprot_id": "LRP6_MOUSE", "id": "O88572-1", "name": "Low-density lipoprotein receptor-related protein 6", "aln": "------------------------------------------------------------------MGAVLRSLLACSFCVLLRAAPLLLYANRRDLRLVDATN--GKENATIVVGGLEDAAAVDFVFGHGLIYWSDVSEEAIKRTEFNK-------SESVQNVVVSGLLSPDGLACDWLGEKLYWTDSETNRIEVSNLDGSLRKVLFWQELDQPRAIALDPSSGFMYWTDWGEVPKIERAGMDGS--SRFVIINTEIYWPNGLTLDYQERKLYWADAKLNFIHKSNLDGTNRQAVVKGSLPHPFALTLFEDTLYWTDWNTHSILACNKYTGEGLREIHSNIFSPMDIHAFSQQRQPNATNPCGIDNGGCSHLCLMSPVKPFYQCACPTGVKLMENGKTCKDGATELLLLARRTDLRRISLDTPDFTDIVLQLEDIRHAIAIDYDPVEGYIYWTDDEVRAIRRSFIDGSGSQFVVTAQIAHPDGIAVDWVARNLYWTDTGTDRIEVTRLNGTMRKILISEDLEEPRAIVLDPMVGYMYWTDWG-EIPKIERAALDGSDRVVLVNTSLGWPNGLALDYDEGTIYWGDAKTDKIEVMNTDGTGRRVLVEDKIPHIFGFTLLGDYVYWTDWQRRSIERVHKRS-AEREVIIDQLPDLMGLKATSVHRVIGSNPCAEDNGGCSHLCLYRPQGLRCACPIGFELIGDMKTCIVPEAFLLFSRRADIRRISLETN---NNNVAIPLTGVKEASALDFDVTDNRIYWTDISLKTISRAFMNGSALEHVVEFGLDYPEGMAVDWLGKNLYWADTGTNRIEVSKLDGQHRQVLVWKDLDSPRALALDPAEGFMYWTEWGGKPKIDRAAMDGSERTTLVPNVGRANGLTIDYAKRRLYWTDLDT-NLIESSDMLGLNREVIA-DDLPHPFGLTQYQDYIYWTDWSRRSIERANKTSGQNRTIIQGHLDYVMDILVFHSSRQAGWNECASSNGHCSHLCLAVPVG-GFVCGCPAHYSLNADNRTCSAPSTFLLFSQKSAINRMVIDEQQSPDIILPIHSLRNVRAIDYDPLDKQLYWIDSRQNSIRKAHEDGGQGFNVVANSVANQNLEIQPYDLSIDIYSRYIYWTCEATNVIDVTRLDGRSVGVVLKGEQDRPRAIVVNPEKGYMYFTNLQERSPKIERAALDGTEREVLFFSGLSKPIALALDSKLGKLFWADSDLRRIESSDLSGANRIVLEDSNILQPVGLTVFENWLYWIDKQQQMIEKIDMTGREGRTKVQARIAQLSDIHAVKELNLQEYRQHPCAQDNGGCSHICLVKGDGTTR----CSCPMHLVLLQDELSCGEPPTCSPQQFTCFT-------GDIDCIPVAWRCDGFTECEDHSDELNCPVCSESQFQCASGQCIDGALRCNGDANCQDKSDEKNCEVLCLIDQFRC-ANGQCVGKHKKCDHSVDCSDRSDELDCYPTEEPAPQATNTVGSVIGVIVTIFVSGTIYFICQRMLCPRMKGDGETMTNDYVVHSPASVPLGYVPHPSSLSGSLPGMSRGKSMISSLSIMGGSSGPPYDRAHVTGASSSSSSSTKGTYFPAILNPPPSPATERSHYTMEFGYSSNSPSTHRSYSYRPYSYRHFAPPTTPCSTDVCD---SDYAP-SRRMTSVATAKGYTS-------DVNYDSEPVPPPPTPRSQYLSAEENY--ESCPPSPYTERSYSHHLYPPPPSPCTDSS----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75581-1", "uniprot_id": "LRP6_HUMAN", "id": "O75581-1", "name": "Low-density lipoprotein receptor-related protein 6", "aln": "------------------------------------------------------------------MGAVLRSLLACSFCVLLRAAPLLLYANRRDLRLVDATN--GKENATIVVGGLEDAAAVDFVFSHGLIYWSDVSEEAIKRTEFNK-------TESVQNVVVSGLLSPDGLACDWLGEKLYWTDSETNRIEVSNLDGSLRKVLFWQELDQPRAIALDPSSGFMYWTDWGEVPKIERAGMDGS--SRFIIINSEIYWPNGLTLDYEEQKLYWADAKLNFIHKSNLDGTNRQAVVKGSLPHPFALTLFEDILYWTDWSTHSILACNKYTGEGLREIHSDIFSPMDIHAFSQQRQPNATNPCGIDNGGCSHLCLMSPVKPFYQCACPTGVKLLENGKTCKDGATELLLLARRTDLRRISLDTPDFTDIVLQLEDIRHAIAIDYDPVEGYIYWTDDEVRAIRRSFIDGSGSQFVVTAQIAHPDGIAVDWVARNLYWTDTGTDRIEVTRLNGTMRKILISEDLEEPRAIVLDPMVGYMYWTDWG-EIPKIERAALDGSDRVVLVNTSLGWPNGLALDYDEGKIYWGDAKTDKIEVMNTDGTGRRVLVEDKIPHIFGFTLLGDYVYWTDWQRRSIERVHKRS-AEREVIIDQLPDLMGLKATNVHRVIGSNPCAEENGGCSHLCLYRPQGLRCACPIGFELISDMKTCIVPEAFLLFSRRADIRRISLETN---NNNVAIPLTGVKEASALDFDVTDNRIYWTDISLKTISRAFMNGSALEHVVEFGLDYPEGMAVDWLGKNLYWADTGTNRIEVSKLDGQHRQVLVWKDLDSPRALALDPAEGFMYWTEWGGKPKIDRAAMDGSERTTLVPNVGRANGLTIDYAKRRLYWTDLDT-NLIESSNMLGLNREVIA-DDLPHPFGLTQYQDYIYWTDWSRRSIERANKTSGQNRTIIQGHLDYVMDILVFHSSRQSGWNECASSNGHCSHLCLAVPVG-GFVCGCPAHYSLNADNRTCSAPTTFLLFSQKSAINRMVIDEQQSPDIILPIHSLRNVRAIDYDPLDKQLYWIDSRQNMIRKAQEDGSQGFTVVVSSVPSQNLEIQPYDLSIDIYSRYIYWTCEATNVINVTRLDGRSVGVVLKGEQDRPRAVVVNPEKGYMYFTNLQERSPKIERAALDGTEREVLFFSGLSKPIALALDSRLGKLFWADSDLRRIESSDLSGANRIVLEDSNILQPVGLTVFENWLYWIDKQQQMIEKIDMTGREGRTKVQARIAQLSDIHAVKELNLQEYRQHPCAQDNGGCSHICLVKGDGTTR----CSCPMHLVLLQDELSCGEPPTCSPQQFTCFT-------GEIDCIPVAWRCDGFTECEDHSDELNCPVCSESQFQCASGQCIDGALRCNGDANCQDKSDEKNCEVLCLIDQFRC-ANGQCIGKHKKCDHNVDCSDKSDELDCYPTEEPAPQATNTVGSVIGVIVTIFVSGTVYFICQRMLCPRMKGDGETMTNDYVVHGPASVPLGYVPHPSSLSGSLPGMSRGKSMISSLSIMGGSSGPPYDRAHVTGASSSSSSSTKGTYFPAILNPPPSPATERSHYTMEFGYSSNSPSTHRSYSYRPYSYRHFAPPTTPCSTDVCD---SDYAP-SRRMTSVATAKGYTS-------DLNYDSEPVPPPPTPRSQYLSAEENY--ESCPPSPYTERSYSHHLYPPPPSPCTDSS----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1Z9D7-1", "uniprot_id": "A1Z9D7_DROME", "id": "A1Z9D7-1", "name": "Low-density lipoprotein receptor-related protein", "aln": "MALEPYTKSAEIEPQLCQVIDNNEDVTTKATKCTKSNSGVGWRQMLIGFLLICFGISNSWQYKNVHMPSSSSLIASPPASAFVNTPATLLFTTRHDIQVANITRPTGGPQIDVIVRDLAEAMAIDFYYAKNLVCWTDSGREIIECAQTNSSALQPLLRAPKQTVISTGLDKPEGLAMDWYTDKIYWTDGEKNRIEVATLDGRYQKVLFWTDLDQPRAVAVVPARKLLIWTDWGEYPKIERASMDGDPLSRMTLVKEHVFWPNGLAVDLKNELIYWTDGKHHFIDVMRLDGSSRRTIVN-NLKYPFSLTFYDDRLYWTDWQRGSLNALDLQTRE-LKELIDTPKAPNSVRAWDPSLQPYEDNPCAHNNGNCSHLCLLATNSQGFSCACPTGVKLISAN-TCANGSQEMMFIVQRTQISKISLDSPDYTIFPLPLGKVKYAIAIDYDPVEEHIYWSDVETYTIKRAHADGTGVTDFVTSEVRHPDGLALDWLARNLYWTDTVTDRIEVCRLDGTARKVLIYEHLEEPRAIAVAPSLGWMFWSDWNERKPKVERASLDGSERVVLVSENLGWPNGIALDIEAKAIYWCDGKTDKIEVANMDGSGRRVVISDNLKHLFGLSILDDYLYWTDWQRRSIDRAHKITGNNRIVVVDQYPDLMGLKVTRLREVRGQNACAVRNGGCSHLCLNRPRDYVCRCAIDYELANDKRTCVVPAAFLLFSRQEHIGRISIEYNEGNHNDERIPFKDVRDAHALDVSVAERRIYWTDQKSKCIFRAFLNGSYVQRIVDSGLIGPDGIAVDWLANNIYWSDAEARRIEVARLDGSSRRVLLWKGVEEPRSLVLEPRRGYMYWTESP-TDSIRRAAMDGSDLQTIVAGANHAAGLTFDQETRRLYWATQSRPAKIESADWDGKKRQILVGSDMDEPYAVSLYQDYVYWSDWNTGDIERVHKTTGQNRSLVHSGMTYITSLLVFNDKRQTGVNPCKVNNGGCSHLCLAQPGRRGMTCACPTHYQLAKDGVSCIPPRNYIIFSQRNCFGRLLPNTTDCPNIPLPVSGK-NIRAVDYDPITHHIYWIEGRSHSIKRSLANG-TKVSLLANSG-------QPFDLAIDIIGRLLFWTCSQSNSINVTSFLGESVGVIDTGDSEKPRNIAVHAMKRLLFWTDVG-SHQAIIRARVDGNERVELAYK-LEGVTALALDQQSDMIYYAHG--KRIDAIDINGKNKKTLVSMHISQVINIAALGGFVYWLDDKT-GVERITVNG-ERRSAELQRLPQITDIRAVWTPDPKVLRNHTCMHSRTKCSHICIASGEGIARTRDVCSCPKHLMLLEDKENCGAFPACGPDHFTCAAPVSGISDVNKDCIPASWRCDGQKDCPDKSDEVGCPTCRADQFSCQSGECIDKSLVCDGTTNCANGHDEADCCKR--PGEFQCPINKLCISAALLCDGWENCADGADESSDICLQRRMAPATDKRAFMILIGATMITIFSIVYLLQ--FCRTRIGKSRTEPKDDQATDPLSPSTLSKSQRVSKIASVADAVRMSTLNSRNSMN------SYDRNHITGASSSTTNGSSMVAYP--INPPPSPATR-----------SRRP-------YRHYKIINQPPPPTPCSTDICDESDSNYTSKSNSNNSNGGATKHSSSSAAACLQYGYDSEPYPPPPTPRSHYHSDVRIVPESSCPPSPSSRSSTYFSPLPPPPSPVQSPSRGFT", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : : : . ..::.:.. **::.*:*:::.: *. * : ::* .* :* *:** :.:.*: *:* ..* *: :: *. . *.*: :** .*:*** ** :*:****.*.*****:.*** :***** :******:*: *: :: ****** ******.***. **: ::: .::*****::* ::. :**:*.* :**. .***:.*:::*: .* :**:**:::* ******. *: * : * * *:*: . :* .::*:. . ** ***. :**.******::. . :.*********:. . ** :*: *::::.:**:: :****:**:* : * * .:::********** ::**:* *. :*:*:. **:* .**::: ****:*:**:********* ****** **:** **:** *.*******.: * *:*:*:**. . **:***:****:*****. .******:*** : *** *.******* * **:****::.*:: *:**:::*.**:**********:*.** : :* *::** *******.* ::.* *.*.** ********* **:. * *.*.:** .* :**:** *******: .* ***:* * :*: **:..*::* ***..*::.****** . * * ***:*** ::::*: ** *:*:*****.:*:**:*: :.****::***. *:**:**.::.**:*.*:* .*:***** . .* *******: *:*....:* ***:* .*****: . ***:: * :*:::. .*: .*:.:: ****:**:**. .***.:**:****::::. : *: .:***:..**:* * * .** ******* * *:.*.**:**.* *. :* .* .:::***:..:.*:: : :.*:* **: . *:**:****: :::***:.*.: *::: :* ..::..* **:**:*** .* ::***. :* *:** : *.****: .*:.::** :.*:. * :::*:: * ** :**.** * :. *. *****.: . :::*.. :**:: *:.* *: .* . :* * :.::.: .::**:*.: :*:* :.* * *: *:.*::**:** : : *:*.* :.. *****:..*:* :* **** **:**:*: .** *:*.*::*** : : ****.:***** .:* *:***:.**.* .**.* **:*** :* *:* :** : ** :* .:*:* * *:. ** :*:* :** . :. . **:. . :* : .*::. :: :: * :* *...* .:* . .* * . .: * .*:.. * .:: * *: .*** *:******::..:. . :* :********. *. * ** *. : .**.******:** *:*:. *. .* . *. ::* : .***** ********:* * . .****** :. * . ****** ..* ", "identical_positions": 698, "similar_positions": 526, "identity": "40.42%" }, { "cls_id": "homologset.agr.MGI:1298219", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88201-1", "uniprot_id": "CLC11_RAT", "id": "O88201-1", "name": "C-type lectin domain family 11 member A", "aln": "MQAAWLLGALLVPHLLSFGHGARGHGKEWEGVWGGALEEERDRESLMLKNLQEALGLPTGVGNKDNLAENSEGKEVWEATETQGEEEEEETTTTPSSSPTPFPSPSPTSEDTVTYILGRLASLDAGLHQLHIRLHVLDTRVVELTQGLRRLRDAASDTRDSVQALKEVQVRSEQEHGRLEGCLKGLRLGHKCFLLSRDFETQAAAQARCKARGGSLAQPADRQQMDALSRYLRAALAPYNWPVWLGVHDRRSEGLYLFENGQRVSFFAWHRALSPESGAQPSAASHPLSPDQPNGGILENCVAQASDDGSWWDHDCERRLYFVCEFPF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88200-1", "uniprot_id": "CLC11_MOUSE", "id": "O88200-1", "name": "C-type lectin domain family 11 member A", "aln": "MQAAWLLGALVVPQLLSFGHGARGPGREWEGGWGGALEEERERESQMLKNLQEALGLPTGVGNEDNLAENPEDKEVWETTETQGEEEEEEITTAPSSSPNPFPSPSPTPEDTVTYILGRLASLDAGLHQLHVRLHVLDTRVVELTQGLRQLRDAASDTRDSVQALKEVQDRAEQEHGRLEGCLKGLRLGHKCFLLSRDFETQAAAQARCKARGGSLAQPADRQQMDALSRYLRAALAPYNWPVWLGVHDRRSEGLYLFENGQRVSFFAWHRAFSLESGAQPSAATHPLSPDQPNGGVLENCVAQASDDGSWWDHDCERRLYFVCEFPF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y240-1", "uniprot_id": "CLC11_HUMAN", "id": "Q9Y240-1", "name": "C-type lectin domain family 11 member A", "aln": "MQAAWLLGALVVPQLLGFGHGARGAEREWEGGWGGAQEEEREREALMLKHLQEALGLPAGRGDE-NPAGTVEGKEDWEMEEDQGEEEEEEATPTPSSG----PSPSPTPEDIVTYILGRLAGLDAGLHQLHVRLHALDTRVVELTQGLRQLRNAAGDTRDAVQALQEAQGRAEREHGRLEGCLKGLRLGHKCFLLSRDFEAQAAAQARCTARGGSLAQPADRQQMEALTRYLRAALAPYNWPVWLGVHDRRAEGLYLFENGQRVSFFAWHRSPRPELGAQPSASPHPLSPDQPNGGTLENCVAQASDDGSWWDHDCQRRLYYVCEFPF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7T6P7-1", "uniprot_id": "A0A8N7T6P7_DANRE", "id": "A0A8N7T6P7-1", "name": "", "aln": "MTLTKILAAVLGFCALSSCDSADNTTR-------------PPATIITTADLSQAREFNEG---------IVRGRG------DTPDILEPEPTTAVSDM-----------ESTYNYILSRLAAMDQAIHRLNVGQYTLDIKVTQLLEKVSRLDNRLGDTEDAIQQISSYCKDNRKEIGRLEGCQKGRKIGYKCVLAYRVYETYADASKKCQERGGRMAMPRDRKEQEALAEYVKSVFHG-NWPVWLGINDERSEGLYLFEDTTRVTYFQWRK--------------HFLSS-QPDGGKRENCVAMSSDDGDWWDTYCERRMYYLCEFDV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : :*.*:: *. ..* . : .*.:* : * ..: : * * *.: *. *. .***.***.:* .:*:*:: :.** :*.:* : : :* : .**.*::* :.. .:* ****** ** ::*:**.* * :*: * *. :* *** :* * **:: :**:.*:::.: *******::*.*:*******: **::* *:: * **. **:** ***** :****.*** *:**:*::*** .", "identical_positions": 105, "similar_positions": 86, "identity": "32.01%" }, { "cls_id": "homologset.agr.MGI:1298220", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GLQ4-1", "uniprot_id": "A0A8I6GLQ4_RAT", "id": "A0A8I6GLQ4-1", "name": "", "aln": "MCHKPVQKMAEHGEASEDQVSEFDGECLPELSALLGVDAVQLVKSQEEEENKERMKMKKGFNAQMRSEAKRLKTFVTYDAFKSWTPQEMAAAGFYYTGVRHGVQCFCCSLILFGTSLRKVPIESHRKLRPQCEFLSGKDVGNIGKYDIRVKNPETLPRGGRARYHEEEARLESFEDWPFYAHGTSPRVLSAAGFVFTGKRDTVQCFSCGGCLGNWEEGDDPWKEHAKWFPKCEFLQSKKSTEEINQYIQSYTGFLHVAGEHFVNSWVRRELPVVSAYSNDSVFANEGLRMDTFKDWPHESSVAVEALVKAGLFYTGKKDIVQCFSCGGCMENWKEGDDPIEDHTKFFPNCVFLQTLKSSAEVIPALQSHCACPEAMETTSESNHEDPVAVHSSVAGLGQSEAQWCQEARSLSEQLRGTYTKASFRHMNLPEAYSSLGTDHLLGCEVFLISKHVSRPVQVALTIPEVFANLSSVMCVEGEAGSGKTTFLKRIAFLWASGCCPLLNRFQLVFYLSLRSIRADQGLADIICAQLLEAGGCISEVSLSSGIQHLQHQVLFLLDDYSGMDSLPQALDTLITKNYLSRTCLLMAVHTNRVRDIRPYLETVLQIKEFPFYNTISVLRKFFSHNTTRLLEFMVYFGRNEDLQGVHKTPLFVAAVCTDWFQNPSDQ-PFQDVTIFKSYMQYLFLKHKATAGPLQATVSSCGHLALTGLFSSSFEFSSDDLIEAGVDEDEELSTCLMSKFTAQRLRPVYRFLSPLFQEFLAAMRLSELLGSDSQEDQDLGLYYLRQINSPLKAINSYGIFLKYVSDHCSSKAGPKVVSHLLQLVDEKESLENMSENEDYMKLHPETFLWLHFLRGLWLNSPESFSSLLSERLLNIALNFAYQSSTVAACSPVILQFLRGRTLALGVLNSQYFWDHPESLLLLGSLKVSINGNEISSHVDYS-FKTYFENLQPPAIDKEYTSAFEHISEWKRNFAEDEKIIKHYQNIWPRVLPDISEGYWKLSPKPYKIPRLEVGVNNMGPADQALLHVLMEVFSASQSIEFQLFNSSGFLESIRPALELNKTSVTKCSMSRLELSRAEQELLLTLPALQSLEVSETNQIPDQLFHNLDKFLGLKELSVRLDGTQDVLSVLPGEFPNLHHMEKLSIHTFTESDLSKLVKLIQNSPNLHDIHLKCDFLSNCESLMAALASCEKLREIEFSGRCFEAMPFVTLLPNFVFLKILNLKGQQFPDKETSEMFAQALGSLRKLEELHLPKGDGIHQVAKLIVQQCLQLPCLRVLAFHHVLDDDSVTEVARVATSRGFQKLENLDLSMNHKITEEGYRNFFQALDNLPNLQELNICRHIRECIQVQASTVKALGQCVSRLPSLTRLRMLSWLLDEEDMKVINDVKERHPQSKRLTVFWKWIVPFSPVVQE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R016-1", "uniprot_id": "BIR1E_MOUSE", "id": "Q9R016-1", "name": "Baculoviral IAP repeat-containing protein 1e", "aln": "--------MAEHGESSEDRISEIDYEFLPELSALLGVDAFQVAKSQEEEEHKERMKMKKGFNSQMRSEAKRLKTFETYDTFRSWTPQEMAAAGFYHTGVRLGVQCFCCSLILFGNSLRKLPIERHKKLRPECEFLQGKDVGNIGKYDIRVKRPEKMLRGGKARYHEEEARLESFEDWPFYAHGTSPRVLSAAGFVFTGKRDTVQCFSCGGSLGNWEEGDDPWKEHAKWFPKCEFLQSKKSSEEIAQYIQSYEGFVHVTGEHFVKSWVRRELPMVSAYCNDSVFANEELRMDMFKDWPQESPVGVEALVRAGFFYTGKKDIVRCFSCGGCLEKWAEGDDPMEDHIKFFPECVFLQTLKSSAEVIPTLQSQYALPEATETTRESNHGDAAAVHSTVVDLGRSEAQWFQEARSLSEQLRDNYTKATFRHMNLPEVCSSLGTDHLLSCDVSIISKHISQPVQEALTIPEVFSNLNSVMCVEGETGSGKTTFLKRIAFLWASGCCPLLYRFQLVFYLSLSSITPDQGLANIICAQLLGAGGCISEVCLSSSIQQLQHQVLFLLDDYSGLASLPQALHTLITKNYLSRTCLLIAVHTNRVRDIRLYLGTSLEIQEFPFYNTVSVLRKFFSHDIICVEKLIIYFIDNKDLQGVYKTPLFVAAVCTDWIQNASAQDKFQDVTLFQSYMQYLSLKYKATAEPLQATVSSCGQLALTGLFSSCFEFNSDDLAEAGVDEDEKLTTLLMSKFTAQRLRPVYRFLGPLFQEFLAAVRLTELLSSDRQEDQDLGLYYLRQIDSPLKAINSFNIFLYYVSSHSSSKAAPTVVSHLLQLVDEKESLENMSENEDYMKLHPQTFLWFQFVRGLWLVSPESSSSFVSEHLLRLALIFAYESNTVAECSPFILQFLRGKTLALRVLNLQYFRDHPESLLLLRSLKVSINGNKMSSYVDYS-FKTYFENLQPPAIDEEYTSAFEHISEWRRNFAQDEEIIKNYENIRPRALPDISEGYWKLSPKPCKIPKLEVQVNNTDAADQALLQVLMEVFSASQSIEFRLFNSSGFLESICPALELSKASVTKCSMSRLELSRAEQELLLTLPALQSLEVSETNQLPEQLFHNLHKFLGLKELCVRLDGKPNVLSVLPREFPNLLHMEKLSIQTSTESDLSKLVKFIQNFPNLHVFHLKCDFLSNCESLMAVLASCKKLREIEFSGRCFEAMTFVNILPNFVSLKILNLKDQQFPDKETSEKFAQALGSLRNLEELLVPTGDGIHQVAKLIVRQCLQLPCLRVLTFHDILDDDSVIEIARAATSGGFQKLENLDISMNHKITEEGYRNFFQALDNLPNLQELNICRNIPGRIQVQATTVKALGQCVSRLPSLIRLHMLSWLLDEEDMKVINDVKERHPQSKRLIIFWKLIVPFSPVILE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13075-1", "uniprot_id": "BIRC1_HUMAN", "id": "Q13075-1", "name": "Baculoviral IAP repeat-containing protein 1", "aln": "--------MATQQKASDERISQFDHNLLPELSALLGLDAVQLAKELEEEEQKERAKMQKGYNSQMRSEAKRLKTFVTYEPYSSWIPQEMAAAGFYFTGVKSGIQCFCCSLILFGAGLTRLPIEDHKRFHPDCGFLLNKDVGNIAKYDIRVKNLKSRLRGGKMRYQEEEARLASFRNWPFYVQGISPCVLSEAGFVFTGKQDTVQCFSCGGCLGNWEEGDDPWKEHAKWFPKCEFLRSKKSSEEITQYIQSYKGFVDITGEHFVNSWVQRELPMASAYCNDSIFAYEELRLDSFKDWPRESAVGVAALAKAGLFYTGIKDIVQCFSCGGCLEKWQEGDDPLDDHTRCFPNCPFLQNMKSSAEVTPDLQSRGELCELLETTSESNLEDSIAVGPIVPEMAQGEAQWFQEAKNLNEQLRAAYTSASFRHMSLLDISSDLATDHLLGCDLSIASKHISKPVQEPLVLPEVFGNLNSVMCVEGEAGSGKTVLLKKIAFLWASGCCPLLNRFQLVFYLSLSSTRPDEGLASIICDQLLEKEGSVTEMCVRNIIQQLKNQVLFLLDDYKEICSIPQVIGKLIQKNHLSRTCLLIAVRTNRARDIRRYLETILEIKAFPFYNTVCILRKLFSHNMTRLRKFMVYFGKNQSLQKIQKTPLFVAAICAHWFQYPFDP-SFDDVAVFKSYMERLSLRNKATAEILKATVSSCGELALKGFFSCCFEFNDDDLAEAGVDEDEDLTMCLMSKFTAQRLRPFYRFLSPAFQEFLAGMRLIELLDSDRQEHQDLGLYHLKQINSPMMTVSAYNNFLNYVSSLPSTKAGPKIVSHLLHLVDNKESLENISENDDYLKHQPEISLQMQLLRGLWQICPQAYFSMVSEHLLVLALKTAYQSNTVAACSPFVLQFLQGRTLTLGALNLQYFFDHPESLSLLRSIHFPIRGNKTSPRAHFSVLETCFDKSQVPTIDQDYASAFEPMNEWERNLAEKEDNVKSYMDMQRRASPDLSTGYWKLSPKQYKIPCLEVDVNDIDVVGQDMLEILMTVFSASQRIELHLNHSRGFIESIRPALELSKASVTKCSISKLELSAAEQELLLTLPSLESLEVSGTIQSQDQIFPNLDKFLCLKELSVDLEGNINVFSVIPEEFPNFHHMEKLLIQISAEYDPSKLVKLIQNSPNLHVFHLKCNFFSDFGSLMTMLVSCKKLTEIKFSDSFFQAVPFVASLPNFISLKILNLEGQQFPDEETSEKFAYILGSLSNLEELILPTGDGIYRVAKLIIQQCQQLHCLRVLSFFKTLNDDSVVEIAKVAISGGFQKLENLKLSINHKITEEGYRNFFQALDNMPNLQELDISRHFTECIKAQATTVKSLSQCVLRLPRLIRLNMLSWLLDADDIALLNVMKERHPQSKYLTILQKWILPFSPIIQK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** : ::*::::*::* : *********:**.*:.*. ****:*** **:**:*:************ **:.: ** **********.***: *:*********** .* ::*** *::::*:* ** .******.*******. :. ***: **:****** **.:****.:* ** *** ********:**********.************************:****:*** ****** **:.::*****:***:****:.***.***:** * **:* *****:**.*.* **.:**:**** ****:*******:*:* *****::** : **:* ***.:****** * ***: * *** *** *. ** . * :.:.**** ***:.*.**** **.*:****.* : *.*.*****.*:: : ***:*:*** .*.:****.**.********:*****.:**:************* ********** * .*:***.*** *** *.::*:.: . **:*::*********. : *:**.: .** **:*******:**:***.**** ** * *:*: ******:.:***:***: : ::::** *:.** : ********:*:.*:* . *:**::*:***: * *: **** *:*******.***.*:**..***..*** ********.*: ************.****.* ******.:** ***.** **.******:*:**:**: ::.::. ** ***. *:**.*.:*****:***:******:***:**:* :*: * ::::**** .*:: *::**:** :** **:*.*** ***.:****:*:**:* .** *** ****** ** *::..*.**: *. ..:* ::* *:: * *:**::*:**** :.**.**:*:.*. :* * :: *. **:* ******** *** *** **: . ..* :*.:** ****** **::* :* **:*** *****.*:******:*:**** **********:*:***** * * :*:* **.*** ****.* *:*. :*:**:* ****: ***** *: :* * *****:*** **** :****:*:*: ***: *.**:** **:**. *:*:.** ****: ******:.*****:**** ** **** :**** :*.****::*****::** ** *****:*.. *:**** *:*:.* * ********.:*:******************:******:*.*:: *:.**:***:*.*** *** * **.******* :*: ::* :******** * :: * *:****:: :", "identical_positions": 876, "similar_positions": 326, "identity": "62.04%" }, { "cls_id": "homologset.agr.MGI:1298222", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GLQ4-1", "uniprot_id": "A0A8I6GLQ4_RAT", "id": "A0A8I6GLQ4-1", "name": "", "aln": "MCHKPVQKMAEHGEASEDQVSEFDGECLPELSALLGVDAVQLVKSQEEEENKERMKMKKGFNAQMRSEAKRLKTFVTYDAFKSWTPQEMAAAGFYYTGVRHGVQCFCCSLILFGTSLRKVPIESHRKLRPQCEFLSGKDVGNIGKYDIRVKNPETLPRGGRARYHEEEARLESFEDWPFYAHGTSPRVLSAAGFVFTGKRDTVQCFSCGGCLGNWEEGDDPWKEHAKWFPKCEFLQSKKSTEEINQYIQSYTGFLHVAGEHFVNSWVRRELPVVSAYSNDSVFANEGLRMDTFKDWPHESSVAVEALVKAGLFYTGKKDIVQCFSCGGCMENWKEGDDPIEDHTKFFPNCVFLQTLKSSAEVIPALQSHCACPEAMETTSESNHEDPVAVHSSVAGLGQSEAQWCQEARSLSEQLRGTYTKASFRHMNLPEAYSSLGTDHLLGCEVFLISKHVSRPVQVALTIPEVFANLSSVMCVEGEAGSGKTTFLKRIAFLWASGCCPLLNRFQLVFYLSLRSIRADQGLADIICAQLLEAGGCISEVSLSSGIQHLQHQVLFLLDDYSGMDSLPQALDTLITKNYLSRTCLLMAVHTNRVRDIRPYLETVLQIKEFPFYNTISVLRKFFSHNTTRLLEFMVYFGRNEDLQGVHKTPLFVAAVCTDWFQNPSDQP-FQDVTIFKSYMQYLFLKHKATAGPLQATVSSCGHLALTGLFSSSFEFSSDDLIEAGVDEDEELSTCLMSKFTAQRLRPVYRFLSPLFQEFLAAMRLSELLGSDSQEDQDLGLYYLRQINSPLKAINSYGIFLKYVSDHCSSKAGPKVVSHLLQLVDEKESLENMSENEDYMKLHPETFLWLHFLRGLWLNSPESFSSLLSERLLNIALNFAYQSSTVAACSPVILQFLRGRTLALGVLNSQYFWDHPESLLLLGSLKVSINGNEISSHVDYS-FKTYFENLQPPAIDKEYTSAFEHISEWKRNFAEDEKIIKHYQNIWPRVLPDISEGYWKLSPKPYKIPRLEVGVNNMGPADQALLHVLMEVFSASQSIEFQLFNSSGFLESIRPALELNKTSVTKCSMSRLELSRAEQELLLTLPALQSLEVSETNQIPDQLFHNLDKFLGLKELSVRLDGTQDVLSVLPGEFPNLHHMEKLSIHTFTESDLSKLVKLIQNSPNLHDIHLKCDFLSNCESLMAALASCEKLREIEFSGRCFEAMPFVTLLPNFVFLKILNLKGQQFPDKETSEMFAQALGSLRKLEELHLPKGDGIHQVAKLIVQQCLQLPCLRVLAFHHVLDDDSVTEVARVATSRGFQKLENLDLSMNHKITEEGYRNFFQALDNLPNLQELNICRHIRECIQVQASTVKALGQCVSRLPSLTRLRMLSWLLDEEDMKVINDVKERHPQSKRLTVFWKWIVPFSPVVQE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JIB6-1", "uniprot_id": "BIR1F_MOUSE", "id": "Q9JIB6-1", "name": "Baculoviral IAP repeat-containing protein 1f", "aln": "--------MAEHGESSEDRISEIDYEFLAELSARFGMNLVQLAKSQEEEDHKERMKMKKGFNSQMRSEAKRLKTFESYDTFRSWTPQEMAAAGFYHTGVKLGVQCFCCSLILFGNSLRKLPIERHKKLRPECEFLQGKDVGNIGKYDIRVKSPEKMLRGGKARYHEEEARLESFEDWPFYAHGTSPRALSAAGFVFTGKRDTVQCFSCGGSLGNWEEGDDPWKEHAKWFPKCEFLQSKKSSEEIAQYIQDYEGFVHVTGEHFVKSWVRRELPMVSAYCNDSVFTNEELRMDMFKDWPQESPVGFEALVRAGFFYTGKKDIVRCFSCGGCLEKWAEGDDPMEDHIKFFPECVFLQTLKSSAEVIPTLQSQYALPEATETTRESNHDDAAAVHSTVVDLGRSEAQWFQEARSLSEQLRDTYTKTSFCHMNLPEVCSSLGTDHLLGCDVSIISKHVSQPVQGALTIPEVFSNLSSVMCVEGEAGSGKTTFLKRIAFLWASGCCPLLYRFQLVFYLSLSSITPDQGLANIICTQLLGAGGCISEVCLSSSIQQLQHQVLFLLDDYSGLASLPQALHTLITKNYLFRTCLLIAVHTNRVRDIRPYLGTSLEIQEFPFYNTVFVLRKFFSHDIICVEKLIIYFSENKDLQGVYKTPLFVAAVCNDWNQNASAQDDFQDVTLFHSYMQYLSLKYKATAESLQATVSSCGQLALTGLFSSCFEFNSDDLAEAGVDEDVKLTTFLMSKFTAQRLRPVYRFLGPLFQEFLAAVRLTELLSSDRQEDQDLGLYYLRQIDSPLKAINSFNIFLYYVSSHSSSKAAPTVVSHLLQLVDEKESLENMSENEDYMKLHPQTFLWFQFVRGLWLVSPESFSSFVSEHLLRLALIFAYESNTVAECSPFILQFLRGRTLALRVLNLEYFWDHPESLLLLRSLKVSINGNKMSSYVDYS-FKTYFENLQPPAINEEYTSAFEHVSEWRRNFAQDEEIIKNYENIWPRALPDISEGYWNLSPKPCKIPKLEVQVNNMGPADQALLQVLMEVFSASQSIEFHLFNSSGFLESIRPALELSKASVTKCSMSRLELSRAEQELLLTLPALQSLEVSETNQLPDQLFHNLHKFLGLKELCVRLDGKPDVLSVLPEEFLNLHHMEKLSIRTSTESDLSKLVKFIQNFPNLHVFHLKCDFLSNCESLMTALASCKKLREIEFSGQCFEAMTFVNILPNFVSLKILSLKGQQFADKETSEKFAQALGSLRNLEELLVPTGDGIHQVAKLIVRQCLQLPCLRVLAFHDILDDESVIEIARAATSGSFQKLENLDISMNHKITEEGYRNFFQALDNLPNLQMLNICRNIPGRIQVQATTVKALGHCVSRLPSLTRLGMLSWLLDEEDMKVINDVKERHPQSKRLTIFWKWIVPFSPVVLE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13075-1", "uniprot_id": "BIRC1_HUMAN", "id": "Q13075-1", "name": "Baculoviral IAP repeat-containing protein 1", "aln": "--------MATQQKASDERISQFDHNLLPELSALLGLDAVQLAKELEEEEQKERAKMQKGYNSQMRSEAKRLKTFVTYEPYSSWIPQEMAAAGFYFTGVKSGIQCFCCSLILFGAGLTRLPIEDHKRFHPDCGFLLNKDVGNIAKYDIRVKNLKSRLRGGKMRYQEEEARLASFRNWPFYVQGISPCVLSEAGFVFTGKQDTVQCFSCGGCLGNWEEGDDPWKEHAKWFPKCEFLRSKKSSEEITQYIQSYKGFVDITGEHFVNSWVQRELPMASAYCNDSIFAYEELRLDSFKDWPRESAVGVAALAKAGLFYTGIKDIVQCFSCGGCLEKWQEGDDPLDDHTRCFPNCPFLQNMKSSAEVTPDLQSRGELCELLETTSESNLEDSIAVGPIVPEMAQGEAQWFQEAKNLNEQLRAAYTSASFRHMSLLDISSDLATDHLLGCDLSIASKHISKPVQEPLVLPEVFGNLNSVMCVEGEAGSGKTVLLKKIAFLWASGCCPLLNRFQLVFYLSLSSTRPDEGLASIICDQLLEKEGSVTEMCVRNIIQQLKNQVLFLLDDYKEICSIPQVIGKLIQKNHLSRTCLLIAVRTNRARDIRRYLETILEIKAFPFYNTVCILRKLFSHNMTRLRKFMVYFGKNQSLQKIQKTPLFVAAICAHWFQYPFDPS-FDDVAVFKSYMERLSLRNKATAEILKATVSSCGELALKGFFSCCFEFNDDDLAEAGVDEDEDLTMCLMSKFTAQRLRPFYRFLSPAFQEFLAGMRLIELLDSDRQEHQDLGLYHLKQINSPMMTVSAYNNFLNYVSSLPSTKAGPKIVSHLLHLVDNKESLENISENDDYLKHQPEISLQMQLLRGLWQICPQAYFSMVSEHLLVLALKTAYQSNTVAACSPFVLQFLQGRTLTLGALNLQYFFDHPESLSLLRSIHFPIRGNKTSPRAHFSVLETCFDKSQVPTIDQDYASAFEPMNEWERNLAEKEDNVKSYMDMQRRASPDLSTGYWKLSPKQYKIPCLEVDVNDIDVVGQDMLEILMTVFSASQRIELHLNHSRGFIESIRPALELSKASVTKCSISKLELSAAEQELLLTLPSLESLEVSGTIQSQDQIFPNLDKFLCLKELSVDLEGNINVFSVIPEEFPNFHHMEKLLIQISAEYDPSKLVKLIQNSPNLHVFHLKCNFFSDFGSLMTMLVSCKKLTEIKFSDSFFQAVPFVASLPNFISLKILNLEGQQFPDEETSEKFAYILGSLSNLEELILPTGDGIYRVAKLIIQQCQQLHCLRVLSFFKTLNDDSVVEIAKVAISGGFQKLENLKLSINHKITEEGYRNFFQALDNMPNLQELDISRHFTECIKAQATTVKSLSQCVLRLPRLIRLNMLSWLLDADDIALLNVMKERHPQSKYLTILQKWILPFSPIIQK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** : ::*::::*::* : *.**** :*:: ***.*. ***::*** **:**:*:************ :*:.: ** **********.***: *:*********** .* ::*** *::::*:* ** .******.*******. :. ***: **:****** **.:****.:* ** .** ********:**********.************************:****:*** ****.* **:.::*****:***:****:.***.***:*: * **:* *****:**.*.. **.:**:**** ****:*******:*:* *****::** : **:* ***.:****** * ***: * *** *** :*. ** . * :.:.**** ***:.*.**** :**.:** **.* : *.*.*******:: : ***:*:*** .*.:****.**.**************.:**:************* ********** * .*:***.*** *** *.::*:.: . **:*::*********. : *:**.: .** **:* *****:**:***.**** ** * *:*: ******: :***:***: : ::::**..*:.** : ********:* .* * . *:**::*:***: * *: **** *:*******.***.*:**..***..*** ******* .*: ************.****.* ******.:** ***.** **.******:*:**:**: ::.::. ** ***. *:**.*.:*****:***:******:***:**:* :*: * ::::**** .*::: *::**:** :** **:*.*** ***.:****:****:* .** :**:****** ** *::..*.**: *. ..:* ::* *:: * *:*:::*:**** :.**.**:*:.*. :* * :: *. **:* ***:**** *** *** **::. ..* :*.:** ****** **::* :* **:*********.*:******:*:**** **********:*:***** * * **:* **.*** ****.* *:*. :*:**:* ** *:****** *: :* * *****:*** **** :****:*:*: ***: *.**:** **:**. *:*:.** ****: ****.*:****.*:**** ** **** :**** :*.****::*****::** ** *****:*.. *:*:** *:*:.* * .*******.:*:******************:**** *:*.*:: *:.**:***:*.:** *** * ** ******* :*: ::* :******** **:: ***:****:: :", "identical_positions": 863, "similar_positions": 339, "identity": "61.12%" }, { "cls_id": "homologset.agr.MGI:1298223", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GLQ4-1", "uniprot_id": "A0A8I6GLQ4_RAT", "id": "A0A8I6GLQ4-1", "name": "", "aln": "MCHKPVQKMAEHGEASEDQVSEFDGECLPELSALLGVDAVQLVKSQEEEENKERMKMKKGFNAQMRSEAKRLKTFVTYDAFKSWTPQEMAAAGFYYTGVRHGVQCFCCSLILFGTSLRKVPIESHRKLRPQCEFLSGKDVGNIGKYDIRVKNPETLPRGGRARYHEEEARLESFEDWPFYAHGTSPRVLSAAGFVFTGKRDTVQCFSCGGCLGNWEEGDDPWKEHAKWFPKCEFLQSKKSTEEINQYIQSYTGFLHVAGEHFVNSWVRRELPVVSAYSNDSVFANEGLRMDTFKDWPHESSVAVEALVKAGLFYTGKKDIVQCFSCGGCMENWKEGDDPIEDHTKFFPNCVFLQTLKSSAEVIPALQSHCACPEAMETTSESNHEDPVAVHSSVAGLGQSEAQWCQEARSLSEQLRGTYTKASFRHMNLPEAYSSLGTDHLLGCEVFLISKHVSRPVQVALTIPEVFANLSSVMCVEGEAGSGKTTFLKRIAFLWASGCCPLLNRFQLVFYLSLRSIRADQGLADIICAQLLEAGGCISEVSLSSGIQHLQHQVLFLLDDYSGMDSLPQALDTLITKNYLSRTCLLMAVHTNRVRDIRPYLETVLQIKEFPFYNTISVLRKFFSHNTTRLLEFMVYFGRNEDLQGVHKTPLFVAAVCTDWFQNPSDQPFQDVTIFKSYMQYLFLKHKATAGPLQATVSSCGHLALTGLFSSSFEFSSDDLIEAGVDEDEELSTCLMSKFTAQRLRPVYRFLSPLFQEFLAAMRLSELLGSDSQEDQDLGLYYLRQINSPLKAINSYGIFLKYVSDHCSSKAGPKVVSHLLQLVDEKESLENMSENEDYMKLHPETFLWLHFLRGLWLNSPESFSSLLSERLLNIALNFAYQSSTVAACSPVILQFLRGRTLALGVLNSQYFWDHPESLLLLGSLKVSINGNEISSHVDYS-FKTYFENLQPPAIDKEYTSAFEHISEWKRNFAEDEKIIKHYQNIWPRVLPDISEGYWKLSPKPYKIPRLEVGVNNMGPADQALLHVLMEVFSASQSIEFQLFNSSGFLESIRPALELNKTSVTKCSMSRLELSRAEQELLLTLPALQSLEVSETNQIPDQLFHNLDKFLGLKELSVRLDGTQDVLSVLPGEFPNLHHMEKLSIHTFTESDLSKLVKLIQNSPNLHDIHLKCDFLSNCESLMAALASCEKLREIEFSGRCFEAMPFVTLLPNFVFLKILNLKGQQFPDKETSEMFAQALGSLRKLEELHLPKGDGIHQVAKLIVQQCLQLPCLRVLAFHHVLDDDSVTEVARVATSRGFQKLENLDLSMNHKITEEGYRNFFQALDNLPNLQELNICRHIRECIQVQASTVKALGQCVSRLPSLTRLRMLSWLLDEEDMKVINDVKERHPQSKRLTVFWKWIVPFSPVVQE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QWK5-1", "uniprot_id": "BIR1A_MOUSE", "id": "Q9QWK5-1", "name": "Baculoviral IAP repeat-containing protein 1a", "aln": "--------MAEHGESSEDRISEIDYEFLPELSALLGVDAVQLAKSQEEEEHKERMKMKKGFNSQMRSEAKRLKTFETYDTFRSWTPQEMAAAGFYHTGVKLGVQCFCCSLILFGNSLRKLPIERHKKLRPECEFLQGKDVGNIGKYDIRVKSPEKMLRGGKARYHEEEARLESFEDWPFYAHGTSPRVLSAAGFVFTGKRDTVQCFSCGGSLGNWEEGDDPWKEHAKWFPKCEFLQSKKSSEEIAQYIQGYEGFVHVTGEHFVNSWVRRELPMVSAYCNDSVFANEELRMDTFKDWPHESPVAVDALVRAGLFYTGKKGIVQCFSCGGCMEKCTEGDDPIQEHNKFFPNCVFLQTPKSSAEVIPALQSHCALPEAMETTSESNHDDPAAVHSTVVGLGRSEAQWFQEARSLSEQLRDNYTKATFRHMNLPEVCSSLGTDHLIGCDVSIISKHISQPVQGALTIPEVFSNLSSVMCVEGETGSGKTTFLKRIAFLWASGCCPLLYRFQLVFYLSLSSITPDQGLANIICAQLLGAGGCISEVCLSSIIQQLQHQVLFLLDDYSGLASLPQALHTLITKNYLSRTCLLIAVHTNRVRGIRSYLDTSLEIKEFPLSNTVYILKKFFSHNIKRLLEFMVYFGQNEDLQGIHKTPLFVAAVCTDWFENPSDQPFQDMALFKSYMQYLSLKHKGAAKPLQATVSSCGQLALTGLFSSCFEFNSDDLAEAGVDEDEELTTCLMSKFTAQRLRPVYRFLGPLFQEFLAAMRLTELLSSDRQEDQDLGLYYLRQINSPLKALTTYNNFLKYVFSHPSSKAGPTVVSHLLHLVDETELLENTYKNEDYVNHPPGTSRIMKGLKELWLLSPEYYSSFVSEHLLRIALNFAYESNTVAECSPFILQFLRGRTLALKVLNLQYFRDHPESLLLVKSLEVSINGNKVPKVVDYSVMEKSFETLQPPTIDQDYASAFEQMKEHEKNLSENEETIKSIKNIFPLQPPKISSGYWKLSPKPCKIPRLEVGVTNMGPADQALLQVLMEVFSASQSIEFRLSDSSGFLESIRPALELSKASVTKCSMSRLELSRAEQELLLTLPALQSLEVSETNQLPDQLFHNLHKFLGLKELCVRLDGKPDVLSVLPGEFPNLLHMEKLSIRTSMESDLSKLVKLIQNSPNLHVFHLKCDFLSNCDSLMAVLASCKKLREIEFSGRCFEAMPFVNILPNFISLKILNLISQQFPDKETSEKFAQALGSLRNLEELLVPTGDGIHQVAKLIVRQCLQLPCLRVLAFHYILDNDSVIEIARVATSGGFQKLEKLDLSMNHKITEEGYRNFFQALDNLPNLQNLNICRHIPECIQVQATTVKALGQCVSRLPSLTRLHMLSWLLDEEDMKVINDVKERHPQSKRLIIFWKWIVPFSPVVLE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13075-1", "uniprot_id": "BIRC1_HUMAN", "id": "Q13075-1", "name": "Baculoviral IAP repeat-containing protein 1", "aln": "--------MATQQKASDERISQFDHNLLPELSALLGLDAVQLAKELEEEEQKERAKMQKGYNSQMRSEAKRLKTFVTYEPYSSWIPQEMAAAGFYFTGVKSGIQCFCCSLILFGAGLTRLPIEDHKRFHPDCGFLLNKDVGNIAKYDIRVKNLKSRLRGGKMRYQEEEARLASFRNWPFYVQGISPCVLSEAGFVFTGKQDTVQCFSCGGCLGNWEEGDDPWKEHAKWFPKCEFLRSKKSSEEITQYIQSYKGFVDITGEHFVNSWVQRELPMASAYCNDSIFAYEELRLDSFKDWPRESAVGVAALAKAGLFYTGIKDIVQCFSCGGCLEKWQEGDDPLDDHTRCFPNCPFLQNMKSSAEVTPDLQSRGELCELLETTSESNLEDSIAVGPIVPEMAQGEAQWFQEAKNLNEQLRAAYTSASFRHMSLLDISSDLATDHLLGCDLSIASKHISKPVQEPLVLPEVFGNLNSVMCVEGEAGSGKTVLLKKIAFLWASGCCPLLNRFQLVFYLSLSSTRPDEGLASIICDQLLEKEGSVTEMCVRNIIQQLKNQVLFLLDDYKEICSIPQVIGKLIQKNHLSRTCLLIAVRTNRARDIRRYLETILEIKAFPFYNTVCILRKLFSHNMTRLRKFMVYFGKNQSLQKIQKTPLFVAAICAHWFQYPFDPSFDDVAVFKSYMERLSLRNKATAEILKATVSSCGELALKGFFSCCFEFNDDDLAEAGVDEDEDLTMCLMSKFTAQRLRPFYRFLSPAFQEFLAGMRLIELLDSDRQEHQDLGLYHLKQINSPMMTVSAYNNFLNYVSSLPSTKAGPKIVSHLLHLVDNKESLENISENDDYLKHQPEISLQMQLLRGLWQICPQAYFSMVSEHLLVLALKTAYQSNTVAACSPFVLQFLQGRTLTLGALNLQYFFDHPESLSLLRSIHFPIRGNKTSPRAHFSVLETCFDKSQVPTIDQDYASAFEPMNEWERNLAEKEDNVKSYMDMQRRASPDLSTGYWKLSPKQYKIPCLEVDVNDIDVVGQDMLEILMTVFSASQRIELHLNHSRGFIESIRPALELSKASVTKCSISKLELSAAEQELLLTLPSLESLEVSGTIQSQDQIFPNLDKFLCLKELSVDLEGNINVFSVIPEEFPNFHHMEKLLIQISAEYDPSKLVKLIQNSPNLHVFHLKCNFFSDFGSLMTMLVSCKKLTEIKFSDSFFQAVPFVASLPNFISLKILNLEGQQFPDEETSEKFAYILGSLSNLEELILPTGDGIYRVAKLIIQQCQQLHCLRVLSFFKTLNDDSVVEIAKVAISGGFQKLENLKLSINHKITEEGYRNFFQALDNMPNLQELDISRHFTECIKAQATTVKSLSQCVLRLPRLIRLNMLSWLLDADDIALLNVMKERHPQSKYLTILQKWILPFSPIIQK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** : ::*::::*::* : *********:*****.*. ****:*** **:**:*:************ **:.: ** **********.***: *:*********** .* ::*** *::::*:* ** .******.*******. :. ***: **:****** **.:****.:* ** *** ********:**********.************************:****:*** ****.* **:.::*********:****:.***.***:** * **:*:*****:**.*.* **.:******* *.**********:*: *****:::*.: **** ***. ****** * ***: * :******* :*. ** . * :.:.**** ***:.*.**** **.*:****.* : *.*.****:**:: : ***:*:*** .*.:****.**.********:*****.:**:************* ********** * .*:***.*** *** *.::*:.: . **:*::*********. : *:**.: .** **:*******:**:***.*.** **:* *:** **: **: :*:*:**** .** :******:*:.** ::********:*:.**: * * .*:*:::*****: * *::*.:* *:*******.***.*:**..***..*** ********:*: *************.****.* ******.*** ***.** **.******:*:*****: ::.:*. **:** . *:****.:*****:***:.* *** :*:**:: * :: *: ** .*: : *::**:** :**: **:*.*** ***.:****:****:* .** *** ****** *: *:...*.**: . ..:* ::. *:. * *:**::*:**** :.* ::*::*.*. :* :: *.:* ******** *** ***.*.::. ..* :*.:** ****** **::* .* **:*********.*:******:*:**** **********:*:***** * * **:* **.*** ****.* *:*. :*:**:* ****: ***** *: * * ************** :****:*:*: ***: *.**:** **:**. *:*:*** ****: ****** .*****:**** ** **** :**** :*.****::*****::** ** *****:*. *::*** *:*:** * ******:*.**:******************:****:*:*.**: ***:.**:***:*.*** *** * **.******* :*: ::* :******** * :: ***:****:: :", "identical_positions": 880, "similar_positions": 325, "identity": "62.37%" }, { "cls_id": "homologset.agr.MGI:1298224", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O70161-1", "uniprot_id": "PI51C_MOUSE", "id": "O70161-1", "name": "Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma", "aln": "---------------------------------------------MELEVPDEAES-AEAG------------------AVTAEAAWSAESGAAAGMTQKKAGLAEAPLV----------------TGQPGPGHGKKLGHRGVDASGETTYKKTTSSTLKG---AIQLGIGYTVGNLSSKPERDVLMQDFYVVESIFFPSEGSNLTPAHHFQDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCNEPLIELSNPGASGSVFYVTSDDEFIIKTVMHKEAEFLQKLLPGYYMN---LNQNPRTLLPKFYGLYCVQSGGKNIRVVVMN----NVLPRVVKMHLKFDLKGST-----------YKRRASKKEKEKSLPTYKDLDFMQDMPEGLLLDSDTFGALVKTLQRDCLVLESFKIMDYSLLLGVHNIDQQERERQAE----GAQSKADEKRPVAQK-----------------------------------------------ALYSTAMESIQGGAARGEAIETDDTMGGIPAVNGRGERLLLHIGIIDILQSYRFIKKLEHTWKALVHDGDTVSVHRPSFYAERFFKFMSSTVFRKSS-----SLKSSPSKKGRG-ALLAVKPLGPTAAFSASQIPS-EREDVQYDLRGARSYP-TLEDEGRPDLLPCTPPSFEEATTASIATTLSS-TSLSIPERSPS-DTSEQPRYRRRTQSSGQDGRPQEEP---HAEDLQKITVQVEPVCGVG---------------------------------------------------------VVPKEEGAGVEVPPC-GAS---AAASVEID--AASQASEPASQAS--DEEDAPSTDIYF--------------------------PTDERSWVYSPLHYSAR----PASDGESDT---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5I6B8-1", "uniprot_id": "PI51C_RAT", "id": "Q5I6B8-1", "name": "Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma", "aln": "---------------------------------------------MELEVPDEAES-AEAG------------------AVTAEAAWSAESGAAAGMTQKKAILAEAPLV----------------TGQPGPGHGKKLGHRGVDASGETTYKKTTSSTLKG---AIQLGIGYTVGNLSSKPERDVLMQDFYVVESIFFPSEGSNLTPAHHFQDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCNEPLIELSNPGASGSVFYVTSDDEFIIKTVMHKEAEFLQKLLPGYYMN---LNQNPRTLLPKFYGLYCVQSGGKNIRVVVMN----NVLPRVVKMHLKFDLKGST-----------YKRRASKKEKEKSLPTYKDLDFMQDMPEGLLLDSDTFGALVKTLQRDCLVLESFKIMDYSLLLGVHNIDQQERERQAE----GAQSKADEKRPVAQK-----------------------------------------------ALYSTARESIQGGAARGEAIETDDTMGGIPAVNGRGERLLLHIGIIDILQSYRFIKKLEHTWKALVHDGDTVSVHRPSFYAERFFKFMSSTVFRKSS-----SLKSSPSKKGRG-ALLAVKPLGPTAAFSASQIPS-EREDVQYDLRGARSYP-TLEDEGRPDLLPCTPPSFEEATTASIATTLSS-TSLSIPERSPS-DTSEQPRYRRRTQSSGQDGRPQEEL---HAEDLQKITVQVEPVCGVGV--------------------------------------------------------VVPKEQGAGVEVPPS-GAS---AAATVEVD--AASQASEPASQAS--DEEDAPSTDIYFFAHGRYWLFSPRRRRLRAVTPSHTGAPTDGRSWVYSPLHYSAR----PASDGESDT---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O60331-1", "uniprot_id": "PI51C_HUMAN", "id": "O60331-1", "name": "Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma", "aln": "---------------------------------------------MELEVPDEAES-AEAG------------------AVPSEAAWAAESGAAAGLAQKKAAPTEVLSM----------------TAQPGPGHGKKLGHRGVDASGETTYKKTTSSTLKG---AIQLGIGYTVGHLSSKPERDVLMQDFYVVESIFFPSEGSNLTPAHHFQDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCNEPLIELSNPGASGSLFYVTSDDEFIIKTVMHKEAEFLQKLLPGYYMN---LNQNPRTLLPKFYGLYCVQSGGKNIRVVVMN----NILPRVVKMHLKFDLKGST-----------YKRRASKKEKEKSFPTYKDLDFMQDMPEGLLLDADTFSALVKTLQRDCLVLESFKIMDYSLLLGVHNIDQHERERQAQ----GAQSTSDEKRPVGQK-----------------------------------------------ALYSTAMESIQGGAARGEAIESDDTMGGIPAVNGRGERLLLHIGIIDILQSYRFIKKLEHTWKALVHDGDTVSVHRPSFYAERFFKFMSNTVFRKNS-----SLKSSPSKKGRGGALLAVKPLGPTAAFSASQIPS-EREEAQYDLRGARSYP-TLEDEGRPDLLPCTPPSFEEATTASIATTLSS-TSLSIPERSPS-ETSEQPRYRRRTQSSGQDGRPQEEPP--AEEDLQQITVQVEPACSVEI--------------------------------------------------------VVPKEEDAGVEASPA-GAS---AAVEVETASQASDEEGAPASQAS--DEEDAPATDIYF--------------------------PTDERSWVYSPLHYSAQA--PPASDGESDT---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B5L6-1", "uniprot_id": "A0A8M3B5L6_DANRE", "id": "A0A8M3B5L6-1", "name": "", "aln": "---------------------------------------------MEAAAAEGAASLSEAGDGSP-----------LSGATASEDAGSADD-VDADSISKKAFITEMPSS----------------SGLP--SHGKKIGHRGVDASGETTYKKTTSSALKG---AIQLGIGYTVGNLSSKPERDVLMQDFYVVESIFFPSEGSNLTPAHHFPDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCNEPLIELSNPGASGSVFYLTKDDEFIIKTVMHKEAEFLQKLLPGYYMN---LNQNPRTLLPKFFGLYCVQSGGKNIRMVVMN----NVLPRVVRMHLKYDLKGST-----------YKRRASKKEREKAKPTFKDLDFMQELPDGLMLDTDTYNALVKTLQRDCLVLESFKIMDYSLLLGVHNIDQAAKEQQME----GSQGNSDEKRPLAQK-----------------------------------------------ALYTTAMESIQGASACGEGIDTDDTMGGIPAVNGRGERLLLYIGIIDILQSYRLIKKLEHTWKALVHDGDTVSVHRPSFYADRFLRFMSSTVFRKTS-----SLKSSPSKRGRG-GLAVGKYCGPGAAWSASQLPF-MRDENIYDLRGARSFP-TLEDDGRADVLPCTPPSFEEATTASIATTLSSTTSLSIPERSPS-DTSEHPRYRRHTQSS------HEETM--QDEDQQTITVEVEVEGRYDSEPT------------------------------------------------LVAPQVSPEISEAAETIPEA-SSSSVPASPRIVVESDGGSQASGCTSRASVDEEDDVPITDIYFFCDGSVHVCPPATHRRR-------HIPPEDKSWVYSPLHFSSGPKTLPEDEGESET---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AC58G7V2-1", "uniprot_id": "A0AC58G7V2_DANRE", "id": "A0AC58G7V2-1", "name": "", "aln": "---------------------------------------------MEAAAAGGCSALAEDA---------------------DAVLGCGMEPAEIEAALKKTCLSEMPSS----------------SCHSSSGPEKKIGHRRVDASGETTYKKTTSSALKG---AIQLGIGYTVGNLSSKPERDVLMQDFYVVESIFFPSEGSNLTPAHHYPDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCNEPLIELSNPGASGSIFYVTRDDEFILKTVMHKEAEFLQKLLPGYYMN---LNQNPRTLLPKFFGLYCVQSGGKNIRIVVMN----NVLPRVFRMHLKFDLKGST-----------YKRRASKKEREKNRPTYKDLDFMQDVQDGLLLDVDTYNALLKTLQRDCLVLESFKIMDYSLLLGVHNVEQAERERQME----GSQG-SDEKRPAAQR-----------------------------------------------ALYSTAMESIQGGAACGDSIDTDDTMGGIPAVSGKGERLLLFIGIIDILQSYRLIKKLEHTWKALVHDGDTVSVHRPNFYADRFFRFMSANVFKKST-----SLKASPAKKGRS-VLAVPKFSVPGAAWSASQLPS-ERDENIYDLRGARSFP-VLENDG---LQSCTPPSFEEATTASVATTLSSNTSISIPERSPS-DTSEHPRYRRHTLSLKDAEGRTHEVVDVHEEDQQTITVQVEVKRETEEDEDDRETDASQTHTDPETHIAAETEMVPPPPADSDPADDLETQTASSAPDDQENPPPADSEQQTAADPPEAESRSAESAEANPQTQLPPADPLSQSQSRES-LEEELAANTDIYFVSRIMTGGCYFDFSCVS---------IRVVTIYRYDGLPRFERARLSYHEQLHINGFNP------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W2R3-1", "uniprot_id": "PI5K1_DROME", "id": "Q9W2R3-1", "name": "Phosphatidylinositol 4-phosphate 5-kinase type-1 sktl", "aln": "MDTRVELELEPVGKQDRLKDQPDDENEPLENQLELEQEHKSLLTPVKIPPAQTASPDQEATPSTPPPMSLQPGTSRQLFRDAAMAHGGQETTSLLQQELNNIAATQTPASKLRSASSTLDASISRNPSTTGGKHEKKLGHRRVAEGGEVTYKKIQSKQIMG---SIQLGIQHTVGSLASKPKRDLLMNDFWEMETISFPPDGSSITPAHHYNDFRFKVYAPIAFRYFRDLFGIAPDDFLMSMCASPLRELSNPGASGSIFYLTTDDEFIIKTVQKKECEFLQKLLPGYYMN---LSQNPRTLLPKFFGLYCFHYNSKNVRLVAMN----NLLPSDIKMHCKYDLKGSS-----------FRRKASKAERQKASPTFKDLDFAEHHPNGIFLETDKYNALMSTIKRDCMVLESFQIMDYSLLVGIHNLDLAAKEKREER-ILNARAKLQRKESAAQGPPSLNPDDDAPEADQNQLQAVASYASIPGTSAGAALNRTRSMNRQRLVAHSTALESITADMDVPLEEDEDVPAGGIPARSENDERLILYIGIIDILQSYRLEKKLEHTFKSILYNGDTVSVCRPSFYAKRFQDAMGKQVFKKTPT---FPLKHSPSKRKTS----TTQLRSPASRLPPLSTPTNAVRQPIMTMSGMSTPPPAFDDISEEDITAASTSSLQQQRSSNQSNNNRGETEVALREGNNTRGGSGEPSSTYHTQYSYDSSGRTGSALTSDYSDDESTGTDLSSRLPKLR---------------------------------------------------------THRLTKTSVQVTTVGYVEGVDTPPKGGQDVVHADVNGKTTMTTT-TMLTTTKTAHIQA--------------------------PSYTSTLVLNDLPR-------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38994-1", "uniprot_id": "ITS3_YEAST", "id": "P38994-1", "name": "Phosphatidylinositol 4-phosphate 5-kinase MSS4", "aln": "--------------------------------MSVLRSQPPSVVPLHLTTSTSRKTEQEPSLLHSAIIER------HQDRSVPNSNSNPDSNHRIKKDRNNHTSYHSSSN----------------SESNMESPRLSDGESSTPTSIEELNPTINNSRLVKRNYSISIDPLHDNSNNNTDDDHPNTITSPRPNSTSNKEMQKYSFPEGKESKKITTPSLNSNNCLDLDNSSLVHTDSYIQDLNDDHILLNKRVSRRSSRISAVTATSTTIKQRRNTQDSNLPNIPFHASKHSQILPMDDSDVIKLANGDTSMKPNSATKISHSMTSLPLHPLPQPSQKSKQYHMISKSTTSLPPENDHYYQHSRGTNHNHAANAAAVNNNTTTTTAATGLKRSESATAEIKKMRQSLLHKREMKRKRKTFLVDDDRVLIGNKVSEGHVNFIIAYNMLTGIRVAVSRCSG-------------------------------------------IMKPLTPADFRFTKKLAFDYHGNELTPSSQYAFKFKDYCPEVFRELRALFGLDPADYLVSLTSKYILSELNSPGKSGSFFYYSRDYKYIIKTIHHSEHIHLRKHIQEYYNHVRDNPNTLICQFYGLHRVKMPISFQNKIKHRKIYFLVMNNLFPPHLDIHITYDLKGSTWGRFTNLDKERLAKDRSYRPVMKDLNWLEEGQKIKFGPLKKKTFLTQLKKDVELLAKLNTMDYSLLIGIHDINKAKEDD------------------------------------------------------LQLADTASIEEQPQTQGPIRTGTGTVVRHFFREFEGGIRASDQFNNDVDLIYYVGIIDFLTNYSVMKKLETFWRSLRHDTKLVSAIPPRDYANRFYEFIEDSVDPLPQKKTQSSYRDDPNQKNYKD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. . . * :: . . . *. . . * . .. : :*.:. : . :. .: : . .: : .:. .:. .: . : : : .*.:: .: . : .. . .* : . . :* :.: . * :: : * : :: * ..: .. . *. : ** : ::.: ..: ::: .. ... .: : : : :. * :..:::. : ..:: ::*:. ..: : . . : . . *. : : . .. * . .. :. : :: :. * * :: : :: . . ** .* : :.:. :: : . : . . : * :: : .: : : . :. . : : :* . . . : .. . . .: . : ", "identical_positions": 24, "similar_positions": 188, "identity": "2.58%" }, { "cls_id": "homologset.agr.MGI:1298226", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0R915-1", "uniprot_id": "M0R915_RAT", "id": "M0R915-1", "name": "", "aln": "MAAQGEAFEERICEFDDDLVSEFSTLLRVDALQVLKRQQEEDHKTRMKMKKGFNAQMRSEAKRLKTFVTYDTFRSWTPQEMAAAGFYYTGVRHGVQCFCCSLILFATRLRKVPIEVHRKLQPECEFLSGKDVGNIGKYDIRVKSPETLPRGGRARYHEEEARLESFEDWPFYAHGTSPRVLSAAGFVFTGKRDTVQCFSCGGCLGNWEEGDDPWKEHAKWFPKCEFLQSKKSAEEIAKYIQTYEGFLHVTGEHFVNSWVRRELPVVSAYSNDSVFANEGLRMDTFKDWPHESPMAVEALVKAGLFYTGKKDIVQCFSCGGCMENWKEGDDPIEDHTKFFPNCVFLQTLKSSAEVIPALQSHCARPEAMETTSESNHEDGVAVHSSVAGIP---------------------------------TCTSLPSADLGQSEAQWCQEARSLSEQLRGTYTKASFRHMNLPEAYSSLGTDHLLGCEVFLISKHVSRPVQVALTIPEVFANLSSVMCVEGEAGSGKTTFLKRIAFLWASGCCPLLNRFQLVFYLSLRSIRADQGLADIICAQLLEAGGCISEVSLSSGIQHLQHQVLFLLDDYSGMDSLPQALDTLITKNYLSRTCLLMAVHTNRVRDIRPYLETVLQIKEFPFYNTVYILKKIFSHDIIRVRRFINYFGFHEYLQGIHKTPLFVAGVCADWLQNPSDQPFQDVTIFKSYMQYLFLKHKATAGPLQATVSSCGHLALTGLFSSSFEFSSDDLIEAGVDEDEELSTCLMSKFTAQRLRPVYRFLSPLFQEFLAAMRLSELLGSDSQEDQDLGLYYLRQINSPLKAMSIYHTFLRYVSNHPSSKAGPKVISHLLQLVDEKESPENTSENEDYMKLHPETLLWSQCLRGLLQLSPESFSLFISERLLNIALNFAYQSNTVAACSPVILQFLQGRTLDLKVLNLQYFWDHPETLLLLKSIQVLFNGNNRVQRIDFSLMDKSFEKIQPPTIDQDYAFAFQPMSECQRNLAEKENIIKNYDDMKYQDPLNISSGYWKLSPKPYKIPRLEVGVNNMGPADQALLHVLMEVFSASQSIEFHLFNSSGFLESIRPALELNKTSVTKCSMSRLELSRAEQELLLTLPALQSLEVSGTSQIPDQLFHNLDKFLGLKELSVRLDGTQDMLSVLPGEFPNLHHMEKLSIHTSTESDLSKLVKLIQNSPNLHDFHLKCDFLSNCESLMAALASCKKLREIEFSGRCFEAVPFVNILSNFASLKILNLRNQQFPDKETSEKFAQALGSLRNLEELHLPTGDGIHQVAKPIVRRCLQLPCLRVLVFAETLDDDSVLEIAKGATSGGFQNLENLDLTLNHKITEEGYRNFFQALDNLPNLQNLDISRHIPECIQVQASTVKALGQCVSRLPSLTRLGMLSWLLDEEDMKVINDVKERHPQSKRLTVHWRWVVPFSPVIQK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QUK4-1", "uniprot_id": "BIR1B_MOUSE", "id": "Q9QUK4-1", "name": "Baculoviral IAP repeat-containing protein 1b", "aln": "MAAQGEAVEEIICEFDDDLVSELSTLLRVDALSVLKRQQEEDHKTRMKMKKGFNSQMRSEAKRLKTFETYDKFRSWTPQEMAAAGFYHTGVKLGVQCFCCSLILFSTRLRKLPIENHKKLRPECEFLLGKDVGNIGKYDIRVKSPEKMLRGDKARYHEEEARLESFEDWPFYAHGTSPRVLSAAGFVFTGKRDTVQCFSCGGCLGNWEEGDDPWKEHAKWFPKCEFLQSKKSPEEITQYVQSYEGFLHVTGEHFVNSWVRRELPMVSAYCNDSVFANEELRMDTFKDWPHESPGAVEALVKAGLFYTGKRDIVQCFSCGGCMEKWAEGDNPIEDHTKFFPNCVFLQTLKSSAEVIPALQSHCALPEAMETTSESNHDDAAAVHSTVVDVSPSEAQELEPASSLVSVLCRDQDHSEAQGRGCASSGTYLPSTDLGQSEAQWLQEARSLSEQLRDTYTKATFRHMNLPEVYSSLGTDHLLSCDVSIISKHISQPVQGSLTIPEVFSNLNSVMCVEGEAGSGKTTFLKRIAFLWASGCCPLLYRFQLVFYLSLSSITPGQELAKIICAQLLGAGGCISEVCLSSIIQQLQHQVLFLLDDYSGLASLPQALHTLITKNYLSRTCLLIAVHTNKVRGIRPYLDTSLEIKEFPFYNTVSVLRKLFSHDIMRVRKFINYFGFHEELQGIHKTPLFVAAVCTDWFKNPSDQPFQDVALFKAYMQYLSLKHKGAAKPLQATVSSCGQLALTGLFSSCFEFNSDNLAEAGVDEDEELTTCLMSKFTAQRLRPVYRFLGPLFQEFLAAVRLTELLSSDRQEDQDLGLYYLRQINSPLKAMSIYHTFLKYVSSHPSSKAAPTVVSHLLQLVDEKESLENMSENEDYMKLHPEALLWIECLRGLWQLSPESFSLFISENLLRICLNFAHESNTVAACSPVILQFLRGRTLDLKVLSLQYFWDHPETLLLLKSIKISLNGNNWVQRIDFSLIEKSFEKVQPPTIDQDYAIAFQPINEVQKNLSEKKHIIKKYEDMKHQIPLNISTGYWKLSPKPYKIPKLEVQVTNTGPADQALLQVLMEVFSASQSIEFRLSDSSGFLESIRPALELSKASVTKCSMSRLELSREDQKLLLTLPTLQSLEVSETNQLPDQLFHNLHKFLGLKELCVRLDSKPDVLSVLPGEFPNLHHMEKLSIRTSTESDLSKLVKLIQNSPNLHVFHLKCNFLSNCEPLMTVLASCKKLREIEFSGRCFEAMTFVNILPNFVFLKILNLRDQQFPDKETSEKFAQALGSLRNLEKLFVPTGDGIHQVAKLIVRQCLQLPCLRVLVFAETLDDDSVLEIAKGATRGGFQKLENLDLTLNHKITEEGYRNFFQVLDNLPNLKNLDISRHIPECIQIQAITVKALGQCVSRLPSLTRLGMLSWLLDEEDIKVINDVKERHPQSKRLTVHWRWVVPFSPVIQK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13075-1", "uniprot_id": "BIRC1_HUMAN", "id": "Q13075-1", "name": "Baculoviral IAP repeat-containing protein 1", "aln": "MATQQKASDERISQFDHNLLPELSALLGLDAVQLAKELEEEEQKERAKMQKGYNSQMRSEAKRLKTFVTYEPYSSWIPQEMAAAGFYFTGVKSGIQCFCCSLILFGAGLTRLPIEDHKRFHPDCGFLLNKDVGNIAKYDIRVKNLKSRLRGGKMRYQEEEARLASFRNWPFYVQGISPCVLSEAGFVFTGKQDTVQCFSCGGCLGNWEEGDDPWKEHAKWFPKCEFLRSKKSSEEITQYIQSYKGFVDITGEHFVNSWVQRELPMASAYCNDSIFAYEELRLDSFKDWPRESAVGVAALAKAGLFYTGIKDIVQCFSCGGCLEKWQEGDDPLDDHTRCFPNCPFLQNMKSSAEVTPDLQSRGELCELLETTSESNLEDSIAVGPIVPEMA--------------------------------------------QGEAQWFQEAKNLNEQLRAAYTSASFRHMSLLDISSDLATDHLLGCDLSIASKHISKPVQEPLVLPEVFGNLNSVMCVEGEAGSGKTVLLKKIAFLWASGCCPLLNRFQLVFYLSLSSTRPDEGLASIICDQLLEKEGSVTEMCVRNIIQQLKNQVLFLLDDYKEICSIPQVIGKLIQKNHLSRTCLLIAVRTNRARDIRRYLETILEIKAFPFYNTVCILRKLFSHNMTRLRKFMVYFGKNQSLQKIQKTPLFVAAICAHWFQYPFDPSFDDVAVFKSYMERLSLRNKATAEILKATVSSCGELALKGFFSCCFEFNDDDLAEAGVDEDEDLTMCLMSKFTAQRLRPFYRFLSPAFQEFLAGMRLIELLDSDRQEHQDLGLYHLKQINSPMMTVSAYNNFLNYVSSLPSTKAGPKIVSHLLHLVDNKESLENISENDDYLKHQPEISLQMQLLRGLWQICPQAYFSMVSEHLLVLALKTAYQSNTVAACSPFVLQFLQGRTLTLGALNLQYFFDHPESLSLLRSIHFPIRGNKTSPRAHFSVLETCFDKSQVPTIDQDYASAFEPMNEWERNLAEKEDNVKSYMDMQRRASPDLSTGYWKLSPKQYKIPCLEVDVNDIDVVGQDMLEILMTVFSASQRIELHLNHSRGFIESIRPALELSKASVTKCSISKLELSAAEQELLLTLPSLESLEVSGTIQSQDQIFPNLDKFLCLKELSVDLEGNINVFSVIPEEFPNFHHMEKLLIQISAEYDPSKLVKLIQNSPNLHVFHLKCNFFSDFGSLMTMLVSCKKLTEIKFSDSFFQAVPFVASLPNFISLKILNLEGQQFPDEETSEKFAYILGSLSNLEELILPTGDGIYRVAKLIIQQCQQLHCLRVLSFFKTLNDDSVVEIAKVAISGGFQKLENLKLSINHKITEEGYRNFFQALDNMPNLQELDISRHFTECIKAQATTVKSLSQCVLRLPRLIRLNMLSWLLDADDIALLNVMKERHPQSKYLTILQKWILPFSPIIQK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:* :* :* *.:**.:*:.*:*:** :**:.: *. :**::* * **:**:*:************ **: : ** **********.***: *:**********.: * ::*** *::::*:* ** .******.*******. :. **.: **:****** **.:****.:* ** *** ********:***********************************:****.***::*:*:*:**:.:**********:****:.***.***:** * **:*:*****:**. .* **.******** :***********:*:* ***:*::***: **** ***.:****** * ***: * :******* :*. ** . * :. *.**** ***:.*.**** :**.*:****.* : *.*.*****.*:: : ***:*:*** .*.:****.**.**************.:**:************* ********** * ..: **.*** *** *.::*:.: . **:*::*********. : *:**.: .** **:*******:**:**:.*.** **:* *:** ******* :*:*:***:: *:*:*: *** :: ** *:*******.:*:.*:: * * .*:**::**:**: * *::*.:* *:*******.***.*:**..***..*:* ********:*: *************.****.* ******.:** ***.** **.******:*:*****: ::* *:.**.***. **:**.*.::****:***:*** ** ***:**:* :** * : **** *:.*::: ::**.** :.*: *::*********.:****:**** * .*.****:****:* **:**:. :.**: * .**:::..*:* * ******** **:*:.* ::**:**:. :*.* **: : . ::*:******** **** *** *.: . ..* :*.:** ****** **::* .* **:*********.*:******:*:**** :*:******:*:***** * * **:* **.*** ****.* *:.. :::**:* ****:****** *: *:* * ************** *****:*:*: .**: *.***** **:**. *:*:.** *.** ******..*****:******* **** ***:* :******::*** *:::* ** ***** * :**:****:**** * ****:****.*::**************.***:***::******:.***: ** ***:*.*** *** * **.******* :*: ::* :******** **: :*::****:***", "identical_positions": 886, "similar_positions": 334, "identity": "61.23%" }, { "cls_id": "homologset.agr.MGI:1298227", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62724-1", "uniprot_id": "MCM6_RAT", "id": "Q62724-1", "name": "DNA replication licensing factor MCM6", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LRDEEQTAESIKNQMTVKEWEKVFEMSQDQNLYHNLCTSLFPTIHGNDEVKRGVLLMLFGGVPKTTGEGTSLRGDINVCIVGDPSTAKSQFLKHVDEFSPRAVYTSGKASSASGLTAAVVRDEESHEFVIEAGALMLADNGVCCIDEFDKMDMRDQVAIHEAMEQQTISITKAGVKATLNARTSILAAANPVSGHYDRSKSLKQNINLSAPIMSRFDLFFILVDECNEVTDYAIARRIVDLHSRIEESIDRVYSLDDIRRYLLFARQFKPKISKESEDFIVEQYKRLRQRDGSGITKSSWRITVRQLESMIRLSESMARMHCCDEVQPKHVKEAFRLLNKSIIRVETPDVNLDQE-EEIQMETDEGPGGINGHAD--------SPAPVNGFNG-SGEDASQETVPKPSLRLAFAEYCRISNLIVLHLRKMEE----EEDESALKRSELVNWYLKEIESEIDSEEELINKKRIIEKVVHRLTHYDHVLIELTQAGLKGSSEGSESYEE--DPYLVVNPNYLLED--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97311-1", "uniprot_id": "MCM6_MOUSE", "id": "P97311-1", "name": "DNA replication licensing factor MCM6", "aln": "-------------------------------------------------------------------------------------MDLAAAAEPGAGSQHPEVRDEVAEKCQKLFLDFLEEFQGSDGEI-----KYLQFAEELIRPERNTLVVSFADLEQFN-QQLSTTIQEEFYRVYPYLCRALKTFVK-------------------------------DRKEIPFAKD-------------------------------FYVAFQDLPTRHKIRELTSSRIGLLTRISGQVVRTHPVHPELVSGTFLCLDCQTVIKDVEQQFKYTQPNICRNPVCANRKRFLLDTNKSRFVDFQKVRIQETQAELPRGSIPRSLEVILRAEAVESAQAGDRCDFTGALIVVPDVSKLSTPGARAE---TNSRVSGADGYETEGIRGLRALGVRDLSYRLVFLACHVAPTNPRFGGKE-----------------------LRDEEQTAESIKNQMTVKEWEKVFEMSQDKNLYHNLCTSLFPTIHGNDEVKRGVLLMLFGGVPKTTGEGTSLRGDINVCIVGDPSTAKSQFLKHVDEFSPRAVYTSGKASSAAGLTAAVVRDEESHEFVIEAGALMLADNGVCCIDEFDKMDMRDQVAIHEAMEQQTISITKAGVKATLNARTSILAAANPVSGHYDRSKSLKQNINLSAPIMSRFDLFFILVDECNEVTDYAIARRIVDLHSRIEESIDRVYSLDDIRRYLLFARQFKPKISKESEDFIVEQYKRLRQRDGSGVTKSSWRITVRQLESMIRLSESMARMHCCDEVQPKHVKEAFRLLNKSIIRVETPDVNLDQE-EEIQMETDEGQGGVNGHAD--------SPAPVNRFNG-SSEDASQETVSKPSLRLGFAEYCRISNLIVLHLRKMEE----EEDESALKRSELVNWYLKEIESEIDSEEELINKKTIIEKVVHRLTHYDHVLIELTQAGLKGSSEGSESYEE--DPYLVVNPNYLLED--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14566-1", "uniprot_id": "MCM6_HUMAN", "id": "Q14566-1", "name": "DNA replication licensing factor MCM6", "aln": "-------------------------------------------------------------------------------------MDLAAAAEPGAGSQHLEVRDEVAEKCQKLFLDFLEEFQSSDGEI-----KYLQLAEELIRPERNTLVVSFVDLEQFN-QQLSTTIQEEFYRVYPYLCRALKTFVK-------------------------------DRKEIPLAKD-------------------------------FYVAFQDLPTRHKIRELTSSRIGLLTRISGQVVRTHPVHPELVSGTFLCLDCQTVIRDVEQQFKYTQPNICRNPVCANRRRFLLDTNKSRFVDFQKVRIQETQAELPRGSIPRSLEVILRAEAVESAQAGDKCDFTGTLIVVPDVSKLSTPGARAE---TNSRVSGVDGYETEGIRGLRALGVRDLSYRLVFLACCVAPTNPRFGGKE-----------------------LRDEEQTAESIKNQMTVKEWEKVFEMSQDKNLYHNLCTSLFPTIHGNDEVKRGVLLMLFGGVPKTTGEGTSLRGDINVCIVGDPSTAKSQFLKHVEEFSPRAVYTSGKASSAAGLTAAVVRDEESHEFVIEAGALMLADNGVCCIDEFDKMDVRDQVAIHEAMEQQTISITKAGVKATLNARTSILAAANPISGHYDRSKSLKQNINLSAPIMSRFDLFFILVDECNEVTDYAIARRIVDLHSRIEESIDRVYSLDDIRRYLLFARQFKPKISKESEDFIVEQYKHLRQRDGSGVTKSSWRITVRQLESMIRLSEAMARMHCCDEVQPKHVKEAFRLLNKSIIRVETPDVNLDQE-EEIQMEVDEGAGGINGHAD--------SPAPVNGING-YNEDINQESAPKASLRLGFSEYCRISNLIVLHLRKVEE----EEDESALKRSELVNWYLKEIESEIDSEEELINKKRIIEKVIHRLTHYDHVLIELTQAGLKGSTEGSESYEE--DPYLVVNPNYLLED--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V461-1", "uniprot_id": "MCM6_DROME", "id": "Q9V461-1", "name": "DNA replication licensing factor Mcm6", "aln": "-------------------------------------------------------------------------------------MDVADAQVG-----QLRVKDEVGIRAQKLFQDFLEEFK-EDGEI-----KYTRPAASLESPDRCTLEVSFEDVEKYD-QNLATAIIEEYYHIYPFLCQSVSNYVK-------------------------------DRIGLKTQKD-------------------------------CYVAFTEVPTRHKVRDLTTSKIGTLIRISGQVVRTHPVHPELVSGVFMCLDCQTEIRNVEQQFKFTNPTICRNPVCSNRKRFMLDVEKSLFLDFQKIRIQETQAELPRGCIPRAVEIILRSELVETVQAGDRYDFTGTLIVVPDVSVLAGVGTRAE---NSSRHKPGEG--MDGVTGLKALGMRELNYRMAFLACSVQATTARFGGTD-----------------------LPMSEVTAEDMKKQMTDAEWHKIYEMSKDRNLYQNLISSLFPSIYGNDEVKRGILLQQFGGVAKTTTEKTSLRGDINVCIVGDPSTAKSQFLKQVSDFSPRAIYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGICCIDEFDKMDQRDQVAIHEAMEQQTISIARAGVRATLNARTSILAAANPINGRYDRSKSLQQNIQLSAPIMSRFDLFFILVDECNEVVDYAIARKIVDLHSNIEESVERAYTREEVLRYVTFARQFKPVISQEAGHMLVENYGHLRQRDTGTSGRSTWRITVRQLESMIRLSEAMAKLECSNRVLERHVKEAFRLLNKSIIRVEQPDIHLDDD-EGLDMDDGIQHDIDMENNG--------AAANVDENNG-MDTSASG-AVQKKKFTLSFEDYKNLSTMLVLHMRAEEARCEVEGNDTGIKRSNVVTWYLEQVADQIESEDELISRKNLIEKLIDRLIYHDQVIIPLKTSTLKPRIQVQKDFVEEDDPLLVVHPNYVVE---------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53091-1", "uniprot_id": "MCM6_YEAST", "id": "P53091-1", "name": "DNA replication licensing factor MCM6", "aln": "MSSPFPADTPSSNRPSNSSPPPSSIGAGFGSSSGLDSQIGSRLHFPSSSQPHVSNSQTGPFVNDSTQFSSQRLQTDGSATNDMEGNEPARSFKSRALNHVKKVDDVTGEKVREAFEQFLEDFSVQSTDTGEVEKVYRAQIEFMKIYDLNTIYIDYQHLSMRENGALAMAISEQYYRFLPFLQKGLRRVVRKYAPELLNTSDSLKRSEGDEGQADEDEQQDDDMNGSSLPRDSGSSAAPGNGTSAMATRSITTSTSPEQTERVFQISFFNLPTVHRIRDIRSEKIGSLLSISGTVTRTSEVRPELYKASFTCDMCRAIVDNVEQSFKYTEPTFCPNPSCENRAFWTLNVTRSRFLDWQKVRIQENANEIPTGSMPRTLDVILRGDSVERAKPGDRCKFTGVEIVVPDVTQLGLPGVKPSSTLDTRGISKTTEGLNSGVTGLRSLGVRDLTYKISFLACHVISIGSNIGASSPDANSNNRETELQMAANLQANNVYQDNERDQEVFLNSLSSDEINELKEMVKDEHIYDKLVRSIAPAVFGHEAVKKGILLQMLGGVHKSTVEGIKLRGDINICVVGDPSTSKSQFLKYVVGFAPRSVYTSGKASSAAGLTAAVVRDEEGGDYTIEAGALMLADNGICCIDEFDKMDISDQVAIHEAMEQQTISIAKAGIHATLNARTSILAAANPVGGRYNRKLSLRGNLNMTAPIMSRFDLFFVILDDCNEKIDTELASHIVDLHMKRDEAIEPPFSAEQLRRYIKYARTFKPILTKEARSYLVEKYKELRKDDAQGFSRSSYRITVRQLESMIRLSEAIARANCVDEITPSFIAEAYDLLRQSIIRVDVDDVEMDEEFDNIESQSHAASGNNDDNDDGTGSGVITSEPPADIEEGQSEATARPGTSEKKKTTVTYDKYVSMMNMIVRKIAEVDR-----EGAEELTAVDIVDWYLLQKENDLGSLAEYWEERRLAFKVIKRLVK-DRILMEIHGTRHNLRDLENEENEN-NKTVYVIHPNCEVLDQLEPQDSS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* * : :.:: * .:: ** :*.::*.:* *: *::.*:: **:*:** :*** *:* * .******:*:******:****** * *:**::*********:***********. ::.************:********** ****************::**::***************:.*:*:*. **: *::::***********:::*:*** * :* :***** . :*::: :: ::: **: :** *** :::*: :**:* .**: * :*::***************::*: .* :.: .: **: **.:*****: *:.:*:: : :: : . : . : . .: :* : * . : : .* : .::* :: : . :. ::* *** : .:: * * ..: : *::.** *:::: : : : .:. : .. *::** : ", "identical_positions": 209, "similar_positions": 155, "identity": "20.41%" }, { "cls_id": "homologset.agr.MGI:1298228", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8N1U091-1", "uniprot_id": "A0A8N1U091_DANRE", "id": "A0A8N1U091-1", "name": "", "aln": "-------------------------MKLEVFS--ASRLVDKPLDLCSDMDVNVASPLST--EEELGSDGDCSANSPGPGAPVPDG--------------------------------------------------KAKPYTRRPKPPYSYIALIAMAIRDSNTGRLTLAEINEY--------LMKKFPFFRGSY--TGWRNSVRHNLSLNDCFLKVLRDPSRPWGKDNYWMLNPHSEYTFADGVFRRRRKRISKKILGSA-------------ESPERVPADDSR-LPARDE-------SVSKFSSSFAIDSILSKPFM-RREQ--STDDTCFGTTR---------LMLSAAP------HFLPVAMGYPP-QSRFQVSSEVSNV---FPIYRCNTADISNISRMADIQSS--------LPGLAHSHTTLQEAGFHPFRIDSLLS------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0R4IJS9-1", "uniprot_id": "A0A0R4IJS9_DANRE", "id": "A0A0R4IJS9-1", "name": "", "aln": "MSMHSSSATGSYTALSLFELSEALPMKLEVFC--GSHYDSKPAELCSDAEGSIPSPVSA--EEELGSDGDCVAHSP---APVADT--------------------------------------------------KGKPYTRRPKPPYSYIALIAMAIRDSNSGRLTLAEINDY--------LMKKFPFFRGSY--TGWRNSVRHNLSLNDCFLKVLRDPSRPWGKDNYWMLNPHSEYTFADGVFRRRRKRISKKTGREP-------------EGPVQTHALDSNDSIATPP-------SSGKFTSSFAIESILSRPFR-REDRPVLSPDTWPGGVD---------TVLPYVM------LRSYGALEDPS-MSRRQRD---------FFAFQLPPECLS----IPHTSAA--------VPAPAT-------AGYHPFKIDYLLS------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O70220-1", "uniprot_id": "FOXQ1_MOUSE", "id": "O70220-1", "name": "Forkhead box protein Q1", "aln": "-------------------------MKLEVFVPRAAHGDKMGSDLEGAGSSDVPSPLSAAGDDSLGSDGDCAANSPAAGSGAGDLEGGGGERNSSGGPSAQDGPEATDDSRTQAS-----AAGPCAGGVGGGEGARSKPYTRRPKPPYSYIALIAMAIRDSAGGRLTLAEINEY--------LMGKFPFFRGSY--TGWRNSVRHNLSLNDCFVKVLRDPSRPWGKDNYWMLNPNSEYTFADGVFRRRRKRLSHRTTVSASGLRPEEAPPGPAGTPQPAPAARSSPIARSPARQEERSSPASKFSSSFAIDSILSKPFRSRRDGDSALGVQLPWGAAPCPPLRAYPALLPAAPGGALLPLCAYGASEPTL-LASRGTEVQPAAP---LLLAPLSTAAPAKPFRGPETAGAAHLYCPLRLPTALQAAAACGPGPHLSYPVETLLA------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63244-1", "uniprot_id": "FOXQ1_RAT", "id": "Q63244-1", "name": "Forkhead box protein Q1", "aln": "-------------------------MKLEVFAPRAAHGDKMGSDLEGAGSSDVPSPLSAAGDDSLGSDGDCAANSPAAGSGAGDLEGGGGERNSSGGASTQDDPEVTDGSRTQAS-----PVGPCAGSVGGGEGARSKPYTRRPKPPYSYIALIAMAIRDSAGGRLTLAEINEY--------LMGKFPFFRGSY--TGWRNSVRHNLSLNDCFVKVLRDPSRPWGKDNYWMLNPNSEYTFADGVFRRRRKRLSHRTTVSASGYG-GGSPPGPAGTPQPAPTAGSSPIARSPARQEEGSSPASKFSSSFAIDSILSKPFRSRRDGTPALGVQLPWSAAPCPPLRAYPALLPASSGGALLPLCAYGAAEPTL-LASRGAEVQPAAP---LFVAPLSTAAPAKPFRGPETAGAAHLYCPLRLPTALQAAAACGPGPHLSYRVETLLA------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9C009-1", "uniprot_id": "FOXQ1_HUMAN", "id": "Q9C009-1", "name": "Forkhead box protein Q1", "aln": "-------------------------MKLEVFVPRAAHGDKQGSDLEGAGGSDAPSPLSAAGDDSLGSDGDCAANSPAAGGGARDTQGDG-EQSAGGGPGAEEAIPAAAAAAVVAEGAEAGAAGPGAGGAGSGEGARSKPYTRRPKPPYSYIALIAMAIRDSAGGRLTLAEINEY--------LMGKFPFFRGSY--TGWRNSVRHNLSLNDCFVKVLRDPSRPWGKDNYWMLNPNSEYTFADGVFRRRRKRLSHRAPVPAPGLRPEEAP-GLPAAPPPAPAAPASPRMRSPARQEERASPAGKFSSSFAIDSILRKPFRSRRLRDTAPGTTLQWGAAPCPPLPAFPALLPAAPCRALLPLCAYGAGEPAR-LGAREAEVPPTAPP--LLLAPLPAAAPAKPLRGP-AAGGAHLYCPLRLPAALQAASVRRPGPHLPYPVETLLA------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P40466-1", "uniprot_id": "FKH1_YEAST", "id": "P40466-1", "name": "Fork head protein homolog 1", "aln": "-MSVTSREQKFSGKYSSYTAQDRQGLVNAVTCVLSSSSDPVAVSSDYSNSLSIAREVNAYAKIAGCDWTYYVQKLEVTIGRNTDSLNLNAVPGTVVKKNIDIDLGPAKIVSRKHAAIRFNLESGSWELQIFGRNGAKVNFRRIPTGPDSPPTVLQSGCIIDIGGVQMIFILPEQETIISDYCLNHLMPKLLSTYGTNGNNNPLLRNIIEGSTYLREQRLQEEARLQQLDHLHTPLSSSSDVNPIGDPHGDTIMMEEDEEDENYTRGGIR-PNTYTSSSNNAVTNGNVPHIENPSDLSLDENRYIKPPQSYASMITQAILSTPEGSISLADIYKFISDNYAFYRFSQMAWQNSVRHNLSLNKAFEKVPKRAGQQGKGMNWKISDEVRRDFLNKWNAGKLSKIRRGASVTRQLQLHMSKFGEIPAPESSSIDPRGIKAQKVKKSLQATSSILGESAPQLQRTQLTGQISTTTSMDVTTNANVNNSSLS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * .: . . . :.: . . : . * : * *. * * ::: . . * : : : * :* : .:* .* .*.: :*: .. ::: * ... :: : .* *. : .: : : . : . . : :... : *:: :.: . . : . . :. * ", "identical_positions": 18, "similar_positions": 73, "identity": "3.7%" }, { "cls_id": "homologset.agr.MGI:1298229", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B5DFC9-1", "uniprot_id": "NID2_RAT", "id": "B5DFC9-1", "name": "Nidogen-2", "aln": "-----MSWDPTAGRLAPPSPLSLLLVLVLLSRVGALRPEELFPYG-ESWGDRLLPEGDDESSAAVKLAVPLRFYDAQFSNLYVGTNGIISTQDFPRETQYVDDDFPTDFPAIAPFLADIDTSHSRG--RILYREDTSQAVLSLAARYVRTGFPLTGSSFTPTHAFLATWEHVGAYEEVRRGAAPSGELNTFQAVLASDESDTYALFLYPANGLQFFGTRPKESYNVQLQLPARVGFCRGEADDLKR---EALYFSLTNT-EQSVKNLYQLSNLGIPGAWAFHIGSRLALDNVRPATVGGDHSTARSSALEHSFNHAAALES-YTEDSFDYYNENEEDVEYPPIEPGEALEGHSRIDVSFNSEVNP-------TSPDSDHASPLPHPAPGNWPSYRETESASLDPQTKQGPPVGEVEVLDFKDPAELLDQTGTRTPAPPGADAAFLTPGRED----LGNRDTQSYPEARPVPSEPDVP-VAPLEREILPNYP-ESGHVPPLSGGRYVVGLEDHVSSKDQVFTYNGANRETCEHSHGQCSRHAFCTDYTTGFCCHCQSRFYGNGRHCVPEGAPHRVNGKVSGHLQVGHMPVHFTDVDLHAYIVSNDGRAYTAISQIPQPAAQALLPVLPIGGLFGWLFALEKPGSENGFSLTGATFVHDVEVTFHPGEERVRITQTAEGLDPENYLSLNTNIEGQVPFIPANFTAHIAPYQEFYHHRDSVVTSSSSRSFSLISGSIN-QTRSYRIDQNITYKACSHAPRHLAVPATQQLTVDRAFALYSEEEGVLRFAVTNQIGPV-EVDSAPTAVNPCYDGSHTCDTTARCHPGTGVDYTCECTPGFQGDGRS-----CVDVNECATGFHRCGPNSVCVNLVGSYRCECRSGYEFADDRHTCVLIAPPPNP------------------CLDGSH---------------------------------------TCAPEGQARCIHHG---GSSFSCACLPG----------------------------------------------------------------------------------------------------------------FVGTG-----------------------HQCSDVDECAENR-CHGAAIC--YNTPGSFSCRCQPGYH--------------GDG-------------------------------------------------------------FHCASDTVPEDSISG------------------------------------------------------------LKPCEYQQRYAQAQH---------------------------------------------------------------------------------------------------------------------------------------------------------AHAGSRIHIPQCDDQGNFVPLQCHGSTGFCWCVDQNGHEVPGTQTPPGST-PPHCGPP--PEPTQRP----RTVCERWRESLLEHYGGTPRDDQYVPQCDDLGHFIPLQCHGKSDFCWCVDKDGRELPGTRSQPGTMPACIPTVAPPVVRPTPRPDVTPPA----VGTFLLYAQGQQIGHLPLNG----SRLQKDAARTLLSLHGSIVVGIDYDCRERMVYWTDVAGRTISRASLEAGAEPETIITSGLISPEGLAIDHFRRTMYWTDSGLDKIERAGLDG-SERKVLFHTDLVNPRAITVDPIRGNLYWTDWNREAPKIETSSLDGENRRILIN-KDIGLPNGLTFDPFSKLLCWADAGTKKLECTLPDGTGRRVIQNHLNYPFSVVSYADHFYHTDWRRDGVISVSKDSGQLTDEYLPEQRSH-LYGITAVYPYCPTGRK-------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88322-1", "uniprot_id": "NID2_MOUSE", "id": "O88322-1", "name": "Nidogen-2", "aln": "-----MFRDPTAGWLTPPSPLSLLVMLLLLSRVGALRPDELFPYG-ESWGDQLLPEGDDESSAAVKLAIPLRFYDAQFSSLYVGTNGIISTQDFPRETQYVDDDFPTDFPAIAPFLADIDTSHSRG--RILYREDTSGAVLSLAARYVRTGFPLSGSSFTPTHAFLATWEHVGAYEEVSRGAAPSGELNTFQAVLASDESDTYALFLYPANGLQFFGTRPKESYNVQLQLPARVGFCRGEADDLKR---EALYFSLTNT-EQSVKNLYQLSNLGIPGVWAFHIGSRFALDNVRPATVGGDPSTARSSALEHPFSHAAALES-YTEDSFHYYDENEEDVEYPPVEPGEAPEGHSRIDVSFNSKADPGLVDVGTSSPGSDRASPWPYPAPGNWPSYRETESASLDPQTKQGRPVGEGEVLDFRDPAELLDQMGTRAPAPPEADAALLTPVNED----LGGRNTQSYPEAGPVPSEPDVP-VPPLEGEVLPHYP-ESGHVPPLRGGKYVIGLEDHVGSNDQVFTYNGANLETCEHSHGRCSQHAFCTDYTTGFCCHCQSRFYGNGKHCLPEGAPHRVNGKVSGRLRVGHIPVHFTDVDLHAYIVGNDGRAYTAISHVPQPAAQALLPVLPIGGLFGWLFALEKPGSENGFSLTGATFVHDVEVTFHPGEERVRITQTAEGLDPENYLSIKTNIEGQVPFIPANFTAHITPYKEFYHYRDSVVTSSSSRSFSLTSGSIN-QTWSYHIDQNITYQACRHAPRHLAIPATQQLTVDRAFALYSEDEGVLRFAVTNQIGPV-EVDSAPVGVNPCYDGSHTCDTTARCHPGTGVDYTCECTPGFQGDGRS-----CVDVNECATGFHRCGPNSVCVNLVGSYRCECRSGYEFADDQHTCILIAPPPNP------------------CLDGSH---------------------------------------TCAPEGQARCIHHG---GSSFSCACLPG----------------------------------------------------------------------------------------------------------------FIGTG-----------------------HQCSDVDECAENR-CHEAAIC--YNTPGSFSCRCQPGYR--------------GDG-------------------------------------------------------------FHCTSDTVPEDSISG------------------------------------------------------------LKPCEYQQRYAQTQH---------------------------------------------------------------------------------------------------------------------------------------------------------AYPGSRIHIPQCDDQGNFVPLQCHGSTGFCWCVDRNGHEVPGTQTPPGST-PPHCGPP--PEPTQRP----RTVCERWRESLLEHYGGTPRDDQYVPQCDDLGHFIPLQCHGKSDFCWCVDKDGRELQGTRSQPGTRPACIPTVAPPVVRPTPRPDVTPPS----VGTFLLYAQGQQIGHLPLNG----SRLQKDAARTLLSLHGSIVVGIDYDCRERMVYWTDVAGRTISRASLEAGAEPETIITSGLISPEGLAIDHFRRTMYWTDSGLDKIERAELDG-SERKVLFHTDLVNPRAITVDPIRGNLYWTDWNREAPKIETSSLDGENRRILIN-KDIGLPNGLTFDPFSKLLCWADAGTKKLECTLPDGTGRRVIQNHLNYPFSIVSYADHFYHTDWRRDGVISVNKDSGQFTDEFLPEQRSH-LYGITAVYPYCPTGRK-------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14112-1", "uniprot_id": "NID2_HUMAN", "id": "Q14112-1", "name": "Nidogen-2", "aln": "-----MEGDRVAGRPVLSSLPVLLLLPLLMLRAAALHPDELFPHG-ESWGDQLLQEGDDESSAVVKLANPLHFYEARFSNLYVGTNGIISTQDFPRETQYVDYDFPTDFPAIAPFLADIDTSHGRG--RVLYREDTSPAVLGLAARYVRAGFPRS-ARFTPTHAFLATWEQVGAYEEVKRGALPSGELNTFQAVLASDGSDSYALFLYPANGLQFLGTRPKESYNVQLQLPARVGFCRGEADDLKS---EGPYFSLTST-EQSVKNLYQLSNLGIPGVWAFHIGSTSPLDNVRPAAVGDLSAAHSSVPLGRSFSHATALESDYNEDNLDYYDVNEEEAEYLPGEPEEALNGHSSIDVSFQSKVDT-------------------KPLE---------ESSTLDPHTKEGTSLGEVGGPDLKGQVEPWDERETRSPAPPEVDRDSLAPSWETPPPYPENGSIQPYPDGGPVPSEMDVPPAHPEEEIVLRSYP-ASGHTTPLSRGTYEVGLEDNIGSNTEVFTYNAANKETCEHNHRQCSRHAFCTDYATGFCCHCQSKFYGNGKHCLPEGAPHRVNGKVSGHLHVGHTPVHFTDVDLHAYIVGNDGRAYTAISHIPQPAAQALLPLTPIGGLFGWLFALEKPGSENGFSLAGAAFTHDMEVTFYPGEETVRITQTAEGLDPENYLSIKTNIQGQVPYVSANFTAHISPYKELYHYSDSTVTSTSSRDYSLTFGAIN-QTWSYRIHQNITYQVCRHAPRHPSFPTTQQLNVDRVFALYNDEERVLRFAVTNQIGPV-KEDSDPTPGNPCYDGSHMCDTTARCHPGTGVDYTCECASGYQGDGRN-----CVDENECATGFHRCGPNSVCINLPGSYRCECRSGYEFADDRHTCILITPPANP------------------CEDGSH---------------------------------------TCAPAGQARCVHHG---GSTFSCACLPG----------------------------------------------------------------------------------------------------------------YAGDG-----------------------HQCTDVDECSENR-CHPAATC--YNTPGSFSCRCQPGYY--------------GDG-------------------------------------------------------------FQCIP-----DSTSS------------------------------------------------------------LTPCEQQQRHAQAQY---------------------------------------------------------------------------------------------------------------------------------------------------------AYPGARFHIPQCDEQGNFLPLQCHGSTGFCWCVDPDGHEVPGTQTPPGST-PPHCGPS--PEPTQRP----PTICERWRENLLEHYGGTPRDDQYVPQCDDLGHFIPLQCHGKSDFCWCVDKDGREVQGTRSQPGTTPACIPTVAPPMVRPTPRPDVTPPS----VGTFLLYTQGQQIGYLPLNG----TRLQKDAAKTLLSLHGSIIVGIDYDCRERMVYWTDVAGRTISRAGLELGAEPETIVNSGLISPEGLAIDHIRRTMYWTDSVLDKIESALLDG-SERKVLFYTDLVNPRAIAVDPIRGNLYWTDWNREAPKIETSSLDGENRRILIN-TDIGLPNGLTFDPFSKLLCWADAGTKKLECTLPDGTGRRVIQNNLKYPFSIVSYADHFYHTDWRRDGVVSVNKHSGQFTDEYLPEQRSH-LYGITAVYPYCPTGRK-------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BH70-1", "uniprot_id": "A0A8M2BH70_DANRE", "id": "A0A8M2BH70-1", "name": "", "aln": "MLTSCMCTSCSPKMTRDKIALLFLQLSWAFHHVAGIDRHDIYPYG-MFYGDVTLQEGDDETSKVITLSKPMHFYEAPFTNLYVTTNGIISTQDLPMEKQYVDDGFPTDFPVIAPFLADIDTSKGKG--SIYYRQTESPTVLKRAEADVKRGFPDA--TFSPTHAFIATWENVSAYEEVARSSSPSHRVNTFQVVLAYNEKDTYALFLYPEDGLQFFGTRPKESYNVEIELPARVGFSRGEISYLIFSRTEGPYYSLTSN-EQSVKNLYQKGNIGEPGVWLFHVGNLYSFQNVVPAQQEAVSSKS-----------PTVQDTVFTDEDYT------DEEEYDPIDP----DFQDPTTTEFLEPEPD----------------------------------SSLLERLNQETPLGQ----------SPLQPSVSGPEDLPQPDPHHVQP--ED--------NTQP---QWPLP-----------KHAILQVYPNRVKDVPTHPSDGQVFSVEEKVDFDSGVIHYSTDNKETCERFQQQCSLNAHCTDHSTGFCCHCNSGFYGNGRHCLPNGAPQRVNGKVRGTVLVGGTAVDLGNIDLHAYIVVGDGRAYTAISEVPEPAGWALMPVAPIGGLFGWLFALELPNSLNGFSITGAEFTRRADVTFSPGNQRLSIVQTATGLDNQNYLNVDTHLQGSVPFIPPGATVQMEPFKDTYQYYPSLITSTSVREFKVVSAENGAETFTFQVKQNITYRDCSHRPR--SRLETLELKMERVFVMYVREERILRYAITNKIGPLGAVDPEPENVNPCYSGNHDCDTTARCVPGEGQLFSCQCATGYRGDGRN-----CYDVDECAEGLSSCGAHSHCVNLPGSHRCQCESGFQFGFDGRTCQDVDECGEQPCHAQALCSNSPGSFRCQCQPGYHGDGFQCHPQNGHPKTRCEQHRDSLQSGDGGVPAVGAFIPQCDEEGQYRPLQCH---GSTGHCWCVDNRGQERAGTRTPPGSPPRNCDEPVRPKTHCEQHRDSLQSENGGVPVVGAFIPQCDEEGQYRPQQCHGSTGHCWCVDNRGQERAGTRTPPGSPRVNCDQPVHLRTRCEQHRDSLQSGDGGVPAVGAFIPQCDEEGQYRPQQCHGSTGHCWCVDNR-GQERAGT--RTPPGSPRVNCDQPVRPKTHCEQHRDSLQSGDGGIPVVGAFIPQCDEEGQYRPQQCHGSTGHCWCVDSRGQERAGTRTPPGSPRVNCDQPVRSKTHCEQHRDSLQSGDGGVPVVGAFIPQCDEEGQYRPQQCHGSTGHCWCVDNRGQERAGTRTPPGSPRVNCDQPVRPKTQCEQHRDSLQSGNDGVPVVGAFIPQCDEEGQYRTQQCHGSTGHCWCVDNRGQERAGTRTPPGSPRVNCDQPVRPKTQCEQHRDSLQSGNDGVPVVGAFIPQCDEEGQYRTQQCHGSTGHCWCVDNRGQERAGTRTPPGSPRVNCDQPVRPKTQCEQHRDSLQSGDGGVPAVGAFIPQCDEEGQYRPQQCHGSTGHCWCVDSRGQERAGTRTPPGSP-RVNCDQPVIVPPTQRP----ESVCERWRASLLQQYGGQPDSQHYLPQCDSAGEFNPVQCYGGSSYCWCVDANGREVPGTRSHDAVKPACIPTVASPTVHPLPRPDVTPPP----TGTSLLYAQGQQIGVLPLNG----TQMDKERSSVLLALHGSIVVGIDYDCRERKVYWTDLAGRTINRASLDPGSEPEIIINTALTSPEGLAVDVARRRLFWVDSTLDKIETANLDG-SDRHVLFATDLVNPRAMIVDSSTGTLYWTDWNREAPKIESSSVDGQNRRVLVQ-EGIGLPNALTYDSTMRQVCWADAGTKRLECISPNGTGRRVIQSNLNYPFSMVYFANHYYYTDWRRDGVISLGRDN-QLTDEYLPDQRSH-LYGITVAPPQCL-----------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z877-1", "uniprot_id": "NDG_DROME", "id": "A1Z877-1", "name": "Nidogen", "aln": "-----MPTFGSKLLACLLLSSVILVSGQFEHYLDSLRASELYEFEDGSLGSIHLLPKGDSETIVLQLEQPIHFYGEQYEQLYINTNGILTFN--SEFPEYLNQPFPLEYASIAAFYSNVDTSFSDEGTSISLFESKEQSILDRASSLVRYAFSSQ-SEFEARQVIVATWRNVGYFDSKT------DRLNTFQVALIANEQSTFVQFIYPDGGLNWLQGETAGLG--LPDIRAQAGFVAE----------DGRFYTLNGSGSENARFLSESTNLGVPGVWLFEVAPIENEQNVRSPDN---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AESLTESPALALSCQAHAHQCHEKAECHDKAEGYCCVCGSGFYGNGKSCLANDQPIRVTGTLTGELNK---QPVSEEAKLQSYVVTSEGRTYTTINPLTPELGAQLRLVLPLLTTVPWLFAKSVGGVANGYQLTGGVYTHVSRLQFDSGEN-LHVNQTFEGLNYWDQLSVKIEIYGEVPAVAADAVLILPDYVEEYTFERPGELKS-VQVLNINITEEQ-RVLGLQVEQRILYRSCLRDDEADPSATKVLQKISKVALDYVERDQALRIGAMSKVGVT-------PESNACNDGTADCVENSVCVP-YEDTYRCDCYHGFAAQLDERGVEVCLDIDECATGSHVCDENAVCDNTEGGFNCYCTEG--FEGNGYRCLSNSTADNIEYPPAVEGQAEPTSEPSPNPSPYPDQGQDQEREREDDQYPQPNPYPYPEEQIPQHPDECYRCSKDADCYQGRCTCHEGFDGDGYTCTNICGHG---------------------------------------------------------------------------------------EVWENGRCEPLLLERHDVDPLCDALGECRCPYGYELSEDSQRCTYVQEFDGERNADLIPCDVDENCHINATCNWYGQELRHICTCQPGFR--------------GDG-------------------------------------------------------------YNCDPISDDSCAIRP-------------------------------------------------------DICDVHADCVYEEHLGKSECQCQAG---------------------------------------------------------------------------------------------------------------------------------------------------YTGNGFNCQLAAECQSAEHCGENAFCDDGVCRCQADFERDVSDRCVPAGRCGSVFCGSNAICKWDSAEGVQYCDCLDGYQGDALTGCTSKPLSCHVLNNCGIHATCEPTEDPANYECQCIAGFKGDGYVCIEEQNCLNNPTLCDMNAQCRSTNSGLVCVCNQGFFGNGSLCQERQHQDSDFLIVSQGVMIARVPLNGRNVRPISVAQMAIGLDKDCVEGRVYWGDISTKKIVSTKYD-GTDLRPFITTDIESPEGIAIDVISRRLYWADSAKDTIEVASLDDPSLRAVIINKQLVNPRGIAVDPYREKLFWSDWDRESPKIEMSNLDGTGRELLLGKDDVTLPNSLVVLENSGEVCYADAGTKKVECIEPQNRQIRTISNELSYPFGITFTHDQFYWTDWTTKKVEIVDSLGARQTPIQPPFFGSHKMYGMTVVEQHCPQYQSPCQISNGGCTDSRLCLVNRQAPSGKSCKCTSASTGCTVLAPGY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :* .: ::: . *. * .*. : .: * *::** : .**: ****:: : . :*:: ** ::. **.* :::*** . : : . ::* * *: .*. * . :.::***.:*. ::. .:****..* : ..::. *:** .**::: .. :: *:.** :. :::*... .:..: * : *:* **.* *.:. :** .. : . :*: :* :* * * : *:** * * *****: *:.:. * **.*.: * : : .*::*:* .:**:**:*. :. . * : *: . **** . . **:.::*. :.: : * .*:: : : ** **: : *.:. .: *.** :... . : : : * . . .: : .: .. ::.*.* *: * : . . . .:.:. * : ** . .::* *.* .*. * .: * * : *:* *: .: . * * :*** * *. :: * * *...* * .* * : * : * * *. * : . * . :. * :. : * *: *** :* : * .. :: . :. :..:. :.. . * * * :: .. .*.* *. . : :: . * . * . : : :*. . * : . . .. .* ..: . : : . . . . *: * *: . * :. ::: : . ..: :*:* ** * *** *:: :.* : : *:: . ::.: : ****:*:* * ::*.** *.** * **. * * *:: .:*****.: **. .*:*:**:**:**** *.:** .*.:*: .: ***.*. :*:******::** *:. *.*...*.***.:. :::* *** . * :. . : * * ** :**:*.. * ", "identical_positions": 250, "similar_positions": 356, "identity": "12.65%" }, { "cls_id": "homologset.agr.MGI:1298230", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q60809-1", "uniprot_id": "CNOT7_MOUSE", "id": "Q60809-1", "name": "CCR4-NOT transcription complex subunit 7", "aln": "-------------------------------------------------------------------------------------------------------MPAAT--VDHSQR-------------------------------------------ICEVWACNLDEEMKKIRQVIRKYNYVAMDTEFPGVVARPIGEFRSNADYQYQLLRCNVDLLKIIQLGLTFMNEQGEYPP-GTSTWQFNFKFNLT-------------EDMYAQDSIELLTTSGIQFKKHEEEGIETQYFAELLMTSGVVLCEGVKWLSFHSGYDFGYLIKILTNSNLPEEELDFFEILRLFFPVIYDVKYLMKSCKNLKG-GLQEVAEQLELERIGPQHQAGSDSLLTGMAFFKMREMFFED--HIDDAKY-------------------CGHLYG---LGSGSS-------YVQNGTGNAYEEEASKQS--------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABZ3NNN6-1", "uniprot_id": "A0ABZ3NNN6_RAT", "id": "A0ABZ3NNN6-1", "name": "poly(A)-specific ribonuclease", "aln": "-------------------------------------------------------------------------------------------------------MPAAT--VDHSQR-------------------------------------------ICEVWACNLDEEMKKIRQVIRKYNYVAMDTEFPGVVARPIGEFRSNADYQYQLLRCNVDLLKIIQLGLTFMNEQGEYPP-GTSTWQFNFKFNLTSGTALGPGNPYFWEDMYAQDSIELLTTSGIQFKKHEEEGIETQYFAELLMTSGVVLCEGVKWLSFHSGYDFGYLIKILTNSNLPEEELDFFEILRLFFPVIYDVKYLMKSCKNLKG-GLQEVAEQLELERIGPQHQAGSDSLLTGMAFFKMREMFFED--HIDDAKY-------------------CGHLYG---LGSGSS-------YVQNGTGNAYEEEASKQS--------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UIV1-1", "uniprot_id": "CNOT7_HUMAN", "id": "Q9UIV1-1", "name": "CCR4-NOT transcription complex subunit 7", "aln": "-------------------------------------------------------------------------------------------------------MPAAT--VDHSQR-------------------------------------------ICEVWACNLDEEMKKIRQVIRKYNYVAMDTEFPGVVARPIGEFRSNADYQYQLLRCNVDLLKIIQLGLTFMNEQGEYPP-GTSTWQFNFKFNLT-------------EDMYAQDSIELLTTSGIQFKKHEEEGIETQYFAELLMTSGVVLCEGVKWLSFHSGYDFGYLIKILTNSNLPEEELDFFEILRLFFPVIYDVKYLMKSCKNLKG-GLQEVAEQLELERIGPQHQAGSDSLLTGMAFFKMREMFFED--HIDDAKY-------------------CGHLYG---LGSGSS-------YVQNGTGNAYEEEANKQS--------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q08BM8-1", "uniprot_id": "CNOT7_DANRE", "id": "Q08BM8-1", "name": "CCR4-NOT transcription complex subunit 7", "aln": "-------------------------------------------------------------------------------------------------------MPAAT--VDHSQR-------------------------------------------ICEVWACNLEEEMKRIRQVTRKFNYIAMDTEFPGVVARPIGEFRSNADYQYQLLRCNVDLLKIIQLGLTFMNEQGEYPP-GTSTWQFNFKFNLT-------------EDMYAQDSIELLTSSGIQFKKHEEEGIETMYFAELLMTSGVVLCEGVKWLSFHSGYDFGYLIKILSNSKLPDEEVDFFEILRLFFPIIYDVKYLMKSCKNLKG-GLQEVAEQLELERIGPQHQAGSDSLLTGMAFFKMREMFFED--HIDDAKY-------------------CGHLYG---LGSGSS-------YVQNGTGNAYEEEANKQQS-------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "X2JCC3-1", "uniprot_id": "X2JCC3_DROME", "id": "X2JCC3-1", "name": "poly(A)-specific ribonuclease", "aln": "---------------------------------------------------------------------------------------------------MKWTMPSAISGAPHAHIPSNEECG------------------------------------IRDVWKQNLEEEFRTIRKVVQKYHYVAMDTEFPGVVARPVGEFRSTADYHYQLLRCNVDLLRIIQLGLTFMDDDGKTPP-GYSTWQFNFKFNLS-------------EDMYAQDSIDLLQNSGIQFKKHEEDGIDPIDFAELLMSSGIVLVENIKWLCFHSGYDFGYLLKLLTDQNLPPDESEFFDLLHIYFPNIFDIKYLMKSCKNLKG-GLQEVADQLELRRVGPQHQAGSDALLTGMAFFKMREVQHTNDFHITPVAHDVLFRYLLEHTMNLKPTISCIHLLSRPAYNGGPAPDESAIISSGNGTGNTNSTEQFTSSAYMVTPPNTPGMAKSDAASLSNRHTSISNSFG", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39008-1", "uniprot_id": "POP2_YEAST", "id": "P39008-1", "name": "Poly(A) ribonuclease POP2", "aln": "MQSMNVQPRVLAVGGEQFFSQRQASEQHQQQNMGPQVYSPKVNRARMFPQGMPVNTINGSVNQEMNNAYLLKQKNEPLLTQQQQQQQQQQQPFNIGTPVSVASLPPGLNVLQQQQQQQQQQQQQQQGVGLNRPLASQLPKHLTNQSMPPIFLPPPNYLFVRDVWKSNLYSEFAVIRQLVSQYNHVSISTEFVGTLARPIGTFRSKVDYHYQTMRANVDFLNPIQLGLSLSDANGNKPDNGPSTWQFNFEFDPK-------------KEIMSTESLELLRKSGINFEKHENLGIDVFEFSQLLMDSGLMMDDSVTWITYHAAYDLGFLINILMNDSMPNNKEDFEWWVHQYMPNFYDLNLVYKIIQEFKNPQLQQSSQQQQQQQYSLTTLADELGLPRFSIFTTTGGQSLLMLLSFCQLSK------------------LSMHKFP-----NGTD--------FAKYQGVIYGIDGDQ----------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*.. : : : :** ** .*: **:: :::::::.*** *.:***:* ***..**:** :*.***:*. *****:: : :*: * * *******:*: . ::: : :*::** .***:*:***: **: *::*** **::: :.:.*: :*:.**:*:*:::* :..:* :: :* :: ::* ::*:: : * :::*. **: ::* : .: . *.. .* * . : . * .*. : * : ", "identical_positions": 84, "similar_positions": 104, "identity": "16.44%" }, { "cls_id": "homologset.agr.MGI:1298231", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3KR92-1", "uniprot_id": "TPST1_RAT", "id": "Q3KR92-1", "name": "Protein-tyrosine sulfotransferase 1", "aln": "-MVGKLKQNLLLACLVISSVTVFYLGQHAMECHHRIEERSQPARLENPKATVRTGLDIKANKTFTYHKNMPLIFIGGVPRSGTTLMRAMLDAHPDIRCGEETRVIPRILALKQMWSRSSKEKIRLDEAGVTDEVLDSAMQAFLLEVIVKHGEPAPYLCNKDPFALKSLTYLARLFPNAKFLLMVRDGRASVHSMISRKVTIAGFDLNSYRDCLTKWNRAIETMYNQCMEVGYKKCMLVHYEQLVLHPERWMRTLLKFLHIPWNHSVLHHEEMIGKAGGVSLSKVERSTDQVIKPVNVGALSKWVGKIPPDVLQDMAVIAPMLAKLGYDPYANPPNYGKPDPKILENTRRVHKGEFQLPDFLKEKPQTEQVE--------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70281-1", "uniprot_id": "TPST1_MOUSE", "id": "O70281-1", "name": "Protein-tyrosine sulfotransferase 1", "aln": "-MVGKLKQNLLLACLVISSVTVFYLGQHAMECHHRIEERSQPARLENPKATVRAGLDIKANKTFTYHKDMPLIFIGGVPRSGTTLMRAMLDAHPDIRCGEETRVIPRILALKQMWSRSSKEKIRLDEAGVTDEVLDSAMQAFLLEVIVKHGEPAPYLCNKDPFALKSLTYLARLFPNAKFLLMVRDGRASVHSMISRKVTIAGFDLNSYRDCLTKWNRAIETMYNQCMEVGYKKCMLVHYEQLVLHPERWMRTLLKFLHIPWNHSVLHHEEMIGKAGGVSLSKVERSTDQVIKPVNVGALSKWVGKIPPDVLQDMAVIAPMLAKLGYDPYANPPNYGKPDPKILENTRRVYKGEFQLPDFLKEKPQTEQVE--------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60507-1", "uniprot_id": "TPST1_HUMAN", "id": "O60507-1", "name": "Protein-tyrosine sulfotransferase 1", "aln": "-MVGKLKQNLLLACLVISSVTVFYLGQHAMECHHRIEERSQPVKLESTRTTVRTGLDLKANKTFAYHKDMPLIFIGGVPRSGTTLMRAMLDAHPDIRCGEETRVIPRILALKQMWSRSSKEKIRLDEAGVTDEVLDSAMQAFLLEIIVKHGEPAPYLCNKDPFALKSLTYLSRLFPNAKFLLMVRDGRASVHSMISRKVTIAGFDLNSYRDCLTKWNRAIETMYNQCMEVGYKKCMLVHYEQLVLHPERWMRTLLKFLQIPWNHSVLHHEEMIGKAGGVSLSKVERSTDQVIKPVNVGALSKWVGKIPPDVLQDMAVIAPMLAKLGYDPYANPPNYGKPDPKIIENTRRVYKGEFQLPDFLKEKPQTEQVE--------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9PTE6-1", "uniprot_id": "TPST1_DANRE", "id": "Q9PTE6-1", "name": "Protein-tyrosine sulfotransferase 1", "aln": "-MIGKLKQNLLVACLVISSVTVFYLCRHAMDCHHRIEERSQPL-LSSLHATLRTGQNLST--PFIYNKDMPLIFIGGVPRSGTTLMRAMLDAHPDVRCGEETRVIPRILAMKQMWSRSGREKMRLDEAGVTDEVLDSAMQAFLLEIIVKHGEPANYLCNKDPFALKSLTYLAKIFPHAKFILMVRDGRASVHSMISRKVTIAGFDLSSYRDCLTKWNRAIETMYTQCLEA-ADKCLPVHYEQLVLHPEKWMRTLLRFLNIPWNDAVLHHEELIGKAGGVSLSKVERSTDQVIKPVNVEALSKWVGKIPLDVQRDMAVIAPMLARLGYDPHANPPNYGRPDPLVLDNTRRLQK--------SPEKPNPS-----------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VYB7-1", "uniprot_id": "TPST_DROME", "id": "Q9VYB7-1", "name": "Protein-tyrosine sulfotransferase", "aln": "MRLPYRNKKVTLWVLFGIIVITMFLFKFTELRPTCLFKVDAANELSSQMVRVEKYLTDDNQRVYSYNREMPLIFIGGVPRSGTTLMRAMLDAHPDVRCGQETRVIPRILQLRSHWLKSEKESLRLQEAGITKEVMNSAIAQFCLEIIAKHGEPAPRLCNKDPLTLKMGSYVIELFPNAKFLFMVRDGRATVHSIISRKVTITGFDLSSYRQCMQKWNHAIEVMHEQCRDIGKDRCMMVYYEQLVLHPEEWMRKILKFLDVPWNDAVLHHEEFINKPNGVPLSKVERSSDQVIKPVNLEAMSKWVGQIPGDVVRDMADIAPMLSVLGYDPYANPPDYGKPDAWVQDNTSKLKANRMLWESKAKQVLQMSSSEDDNTNTIINNSNNKDNNNNQYTINKIIPEQHSRQRQHVQQQHLQQQQQQHLQQQQHQRQQQQQQREEESESEREAEPDREQQLLHQKPKDVITIKQLPLAGSNNNNINNNINNNNNNNNIMEDPMADT", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :::: : *. * .::* :.: : : . . *.. . :. . : *:::**************************:***:********* ::. * :* :*.:**:***:*.**::**: * **:*.****** ******::** :*: .:**:***::*******:***:*******:****.***:*: ***:***.*: ** : .:*: *:*********.***.:*:**.:***.:******:*.*..**.*******:********: *:*****:** ** :*** *****: *****:****:**:**. : :** :: : : . ", "identical_positions": 192, "similar_positions": 97, "identity": "38.48%" }, { "cls_id": "homologset.agr.MGI:1298232", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P49864-1", "uniprot_id": "GRAK_RAT", "id": "P49864-1", "name": "Granzyme K", "aln": "---------------------MSFSSSALVFLVAGIYMSSESFHTEIIGGREVQPHSRPFMASIQYRGKHICGGVLIHPQWVLTAAHCYS---RGHSPTVVLGAHS-LSKNEPMKQTFEIK-------EFIPFSGFKSG--TNDIMLIKLRTAAELNKHVQLLHLRSKN-------YIRDGTKCQVTGWGSTKPDVLTTSDTLQEVTVTIISRKRCNSQSYYNHKPVITKDMICAGDRRGEKDSCKGDSGGPLICKGVFHALVS------GGYKCGISNKPGVYTLLTKKYQTWIKSKLAPSSAH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35205-1", "uniprot_id": "GRAK_MOUSE", "id": "O35205-1", "name": "Granzyme K", "aln": "---------------------MRFSSWALVSLVAGVYMSSECFHTEIIGGREVQPHSRPFMASIQYRSKHICGGVLIHPQWVLTAAHCYSWFPRGHSPTVVLGAHS-LSKNEPMKQTFEIK-------KFIPFSRLQSGSASHDIMLIKLRTAAELNKNVQLLHLGSKN-------YLRDGTKCQVTGWGTTKPDLLTASDTLREVTVTIISRKRCNSQSYYNHKPVITKDMICAGDARGQKDSCKGDSGGPLICKGIFHALVS------QGYKCGIAKKPGIYTLLTKKYQTWIKSKLAPSRAH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49863-1", "uniprot_id": "GRAK_HUMAN", "id": "P49863-1", "name": "Granzyme K", "aln": "--------------------MTKFSSFSLFFLIVGAYMTHVCFNMEIIGGKEVSPHSRPFMASIQYGGHHVCGGVLIDPQWVLTAAHCQYRFTKGQSPTVVLGAHS-LSKNEASKQTLEIK-------KFIPFSRVTSDPQSNDIMLVKLQTAAKLNKHVKMLHIRSKT-------SLRSGTKCKVTGWGATDPDSLRPSDTLREVTVTVLSRKLCNSQSYYNGDPFITKDMVCAGDAKGQKDSCKGDSGGPLICKGVFHAIVS------GGHECGVATKPGIYTLLTKKYQTWIKSNLVPPHTN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7KVM8-1", "uniprot_id": "Q7KVM8_DROME", "id": "Q7KVM8-1", "name": "Peptidase S1 domain-containing protein", "aln": "MAHSLIEFKMKWLLVCFILALRSYESLGQDLLDPNCVQTPVGVREQILGGHNADIKLHPWMVQILQRGYHFCGGSLISSLFVLTAAHCHSR----YRLKVRFGRYSGITPRYLCSSQYCSPFGPEIDVKRIFLHSSYRDYHNYDIALFLLAKPVRYNVQTRPICVLQTSNKDKLRQFLNYVAMFNVTGWGKTESQ--LTSTILQTTSLFHLDRKFCAQIF----DRKIGWPHICAGHS--QSSTCTGDSGGPLSAELTFSGVKRTVLFGIISYGAPNCREVTVFTNVLR-YSNWIRDIVHNFTPS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W2G1-1", "uniprot_id": "Q9W2G1_DROME", "id": "Q9W2G1-1", "name": "Peptidase S1 domain-containing protein", "aln": "MKNTKIFVVVVLLAASSVVVLGS-ESG--SFLEHPCGTVPIS-QFKILGGHNAPVASAPWMAMVMGEGGFHCGGTLITNRFVLTSAHCIAN----GELKVRLG----VLEREAEAQKFA--------VDAMFVHTDY-YFDQHDLALLRLAKRVHYSDNISPICLLLDP---LVKNIDEHIVKFRTYGWGKTESR--SSSRMLQKTSLFNLHRSECAKQYP---HQQINRNHICAESA--NANTCNGDSGGPLTAIVTYDHVQMVFQFGVTSFGHADCSKATVFTNVMT-HLDWIVNTVRRAEIM", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* * . :*:**::. *:*. : . . *** ** :***:*** .* :* : . . . : . *: *. * . .. . : : : . . .. *** *.. .* *: .:: : *. * . . * :** : .:*.******* . : : .. . : ::* : : ** . : ", "identical_positions": 45, "similar_positions": 64, "identity": "14.75%" }, { "cls_id": "homologset.agr.MGI:1298234", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88454-1", "uniprot_id": "KCNK4_MOUSE", "id": "O88454-1", "name": "Potassium channel subfamily K member 4", "aln": "MRSTTLLALLALVLLYLVSGALVFQALEQPHEQQAQKKMDHGR----------DQFLRDHPCVSQKSLEDFIKLLVEALGGGAN-PETSWTNSSNHSSAWNLGSAF--FFSGTIITTIGYGNIVLHTDAGRLFCIFYALVGIPLFGMLLAGVGDRLG---SSLRRGIGHIEAIFLK-WHVPPGLVRSLSAVLFLLIGCLLFVLTPTFVFSYMESWSKLEAIYFVIVTLTTVGFGDYVPGDGTGQNS------PAYQPLVWFWILFGLAYFASVLTTIGNWLR---------AVSRRTRAEMGGLTAQAASWTG-----------------------------------------------------TVTARVTQRTG--------------------------------------------PSAPPPEKEQ------------------PLLPSSLPAPPAVVEPAGRPGS------PAPAEK-----VETPS--------------------------------------------------------------------------------------------PPTASALDYPSENLAFIDESSDTQSERG--------------------------------------CALPRAPRGRRRPNPSKKPS--------RPRGPGRLRDKAVPV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3V8V5-1", "uniprot_id": "KCNK4_RAT", "id": "G3V8V5-1", "name": "Potassium channel subfamily K member 4", "aln": "MRSTTLLALLALVLLYLVSGALVFQALEQPHEQQVQKDLEDGR----------DQFLKDHPCVSQKNLEGFIKLVAEALGGGAN-PETSWTNSSNHSSAWNLGSAF--FFSGTIITTIGYGNIALHTDAGRLFCIFYALVGIPLFGMLLAGVGDRLG---SSLRRGIGHIEAVFLK-WHVPPGLVRMLSAVLFLLIGCLLFVLTPTFVFSYMESWSKLEAIYFVIVTLTTVGFGDYVPGDGTGQNS------PAYQPLVWFWILFGLAYFASVLTTIGNWLR---------AVSRRTRAEMGGLTAQAASWTG-----------------------------------------------------TVTARVTQRTG--------------------------------------------PSAPPPEKEQ------------------PLLPSSLPAPPAVAEPAHRPGS------PAPAEK-----VETP---------------------------------------------------------------------------------------------PPTASALDYPSENLAFIDESSDTQSERG--------------------------------------CALPRAPRGRRRPNPTKKPS--------RPRGPGRLRDKAVPV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NYG8-1", "uniprot_id": "KCNK4_HUMAN", "id": "Q9NYG8-1", "name": "Potassium channel subfamily K member 4", "aln": "MRSTTLLALLALVLLYLVSGALVFRALEQPHEQQAQRELGEVR----------EKFLRAHPCVSDQELGLLIKEVADALGGGAD-PETNSTSNSSHS-AWDLGSAF--FFSGTIITTIGYGNVALRTDAGRLFCIFYALVGIPLFGILLAGVGDRLG---SSLRHGIGHIEAIFLK-WHVPPELVRVLSAMLFLLIGCLLFVLTPTFVFCYMEDWSKLEAIYFVIVTLTTVGFGDYVAGADPRQDS------PAYQPLVWFWILLGLAYFASVLTTIGNWLR---------VVSRRTRAEMGGLTAQAASWTG-----------------------------------------------------TVTARVTQRAG--------------------------------------------PAAPPPEKEQ------------------PLLPP----PPCPAQPLGRPRS------PSPPEK-----AQPPS--------------------------------------------------------------------------------------------PPTASALDYPSENLAFIDESSDTQSERG--------------------------------------CPLPRAPRGRRRPNPPRKPV--------RPRGPGRPRDKGVPV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32T5S6-1", "uniprot_id": "A0AB32T5S6_DANRE", "id": "A0AB32T5S6-1", "name": "Potassium channel subfamily K member 4", "aln": "MRYSTLLTILAAVLLYLVLGALVFGWLESSREEWAHRELLTSQ----------MAFLQNHSCVTAYSLREFTEKVVDAIEAGVD-ARS----TSNYTSRWDPSNAF--FFCGTIITTIGFGNISPKTKGGQLFCIFYALVGIPMFGILLAGVGDHLG---TLLRRAVAKVETLFLR-KGVKPTSVRIISAVFSILIGCLVFIAVPTMVFQEVESWSLLEAVYFVVITLTTVGFGDYVAEN-RRDGT------PLYKPLVWLWIVFGLAYFASILTMIGNWLR---------VLSKKTRAEMEELRAHATDWTQNIQNMSMDFRIPVPLDLNDPFQLQRRRRRKRHHHHHHHHRHPRPNTTGLTHGISLDADIIRENGHL--------------------------------ILGWPTCRYKPASEVLSQSRSMSRIDGAHYEMRPGSRLTVGPTSRSISRLELKPASRAGSRAISRSPSQSESGSFSASETPSESWSEYEYESNSCNSEDVESGAKA------------------------------------------------SRRSLESQNDVPIVVVASCSPPRPSLLDFFGENLAYIDESSDALSDRVKP------------------------------------SGQNRQRRPKRRSMTKRQPAGLQREVSNELQPPSHPPTPPPPTS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q94526-1", "uniprot_id": "ORK1_DROME", "id": "Q94526-1", "name": "Open rectifier potassium channel protein 1", "aln": "MSPNRWILLLIFYISYLMFGAAIYYHIEHGEEKISRAEQRKAQ----------IAINEYLLEELGDKNTTTQDEILQRISDYCDKPVTLPPTYDDTPYTWTFYHAF--FFAFTVCSTVGYGNISPTTFAGRMIMIAYSVIGIPVNGILFAGLGEYFGRTFEAIYRRYKKYKMSTDM-HYVPPQLGLITTVVIALIPGIALFLLLPSWVFTYFENWPYSISLYYSYVTTTTIGFGDYVPTFGANQPKEFGGWFVVYQIFVIVWFIFSLGYLVMIMTFITRGLQSKKLAYLEQQLSSNLKATQNRIWSGVTKDVGYLRRMLNELYILKVKPVYTDVDIAYTLPRSNSCPDLSMYRVEPAPIPSRKRAFSVCADMVAAQREAGMVHANSDTELSKLDREKTFETAEAYRQTTDLLAKVVNALATVKPPPAEQEDAALYGGYHGFSDSQILASEWSFSTVNEFTSPRRPRARACSDFNLEAPRWQSERPLRSSHNEWTWSGDNQQIQEAFNQRYKGQQRANGAANSTMVHLEPDALEEQLKKQSPGAGRVKKFSMPDGLRRLFPFQKKRPSQDLERKLSVVSVPEGVISQQARSPLDYYSNTVTAASSQSYLRNGRGPPPPFESNGSLASGGGGLTNMGFQMEDGATPPSALGGGAYQRKAAAGKRRRESIYTQNQAPSARRGSMYPPTAHALAQMQMRRGSLATSGSGSAAMAAVAARRGSLFPATASASSLTSAPRRSSIFSVTSEKDMNVLEQTTIADLIRALEVVHTHAVLDEQQQAAAAGGAAGGGGISRGSRKQRKMGNAGLEPPQLPPILSLFAGDQTRTLQAAAANRLYARRSTIVGISPTGGAATAPAARSLLEPPPSYTERAANQSQITAGPSNAPTVQSKFRRRFSVRPTALQIPPGQAPPPGASLMEQSSQTALQRRLSLRPSPLARELSPTSPPGGSGSALPAGAIDESGGTSAQRLLPLPAGTRPSTSSTHSPLSRIVQISQAQRKSSMPSAAATGSSGAPAEK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40310-1", "uniprot_id": "TOK1_YEAST", "id": "P40310-1", "name": "Outward-rectifier potassium channel TOK1", "aln": "-MTRFMNSFAKQTLGYGNMATVEQESSAQAVDSHSNNTPKQAKGVLAEELKDALRFRDERVSIINAEPSSTLFVFWFVVSCYFPVITACLGPVANTISIACVVEKWRSLKNNSVVTNPRSNDTDVLMNQVKTVFDPPGIFAVNIISLVLGFTSNIILMLHFSKKLTYLKSQLINITGWTIAGGMLLVDVIVCSLNDMPSIYSKTIGFWFACISSGLYLVCTIILTIHFIGYKLGKYPPTFNLLPNERS---IMAYTVLLSLWLIWGAGMFSGLLHITYGNALY-------FCTVSLLTVGLGDILPKSVGAKIMVLIFSLSGVVLMG------------------------------------LIVFMTRSIIQKSSGP---------------------------------------IFFFHRVEKGRSKSWKHYMDSSKNLSEREAFDLMKCIRQTASRKQHWFSLSVTIAIFMAFWLLGALVFKFAENWSYFNCIYFCFLCLLTIGYGDYAPRTG-----------------------------------------------------AGRAFFVIWALGAVPLMGAILSTVGDLLFDISTSLDIKIGESFN-----------------------------------NKVKSIVFNGRQRALSFMVNTGEIFEESDTADGDLEENTTSSQSSQISEFNDNNSEENDSGVTSPPASLQESFSSLSKAS------------------------------SPEGILPLEYVSSAEYALQDSGTCNLRNLQELLKAVKKLHRICLADKDYTLSFSDWSYIHKLHLRNITDIEEYTRG------PEFWISPDTPLKFPLNEPHFAFMMLFKNIEELVGNLVEDEELYKVISKRKFLGEHRKTL-----------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : * .: :. . : : . . : : . : : :: :. .: : . .:..: : .:::. .: : : : : : : :: * ... . : :*.* . * :: .*:: . . : :: . : . . : : :. . . : . : *. .: : . . . ::* . ", "identical_positions": 8, "similar_positions": 86, "identity": "0.79%" }, { "cls_id": "homologset.agr.MGI:1298366", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F7FD47-1", "uniprot_id": "F7FD47_RAT", "id": "F7FD47-1", "name": "", "aln": "MEDSHKSNTSETASQPGSTVPG-IISQIVHQVSS----------------LSESEESQDSSDSIGSSQKAHG---------------------ILARRPSYRKILKDLSSEDTRGRKGDGENPSIS-AVTSMSVPTPIYQTSSGQYIAIAPNGALQLAS-----------PGPDGVQALQTLTMTNSSSAQQG-----------AILQYAQTSDGQQILVPSNQVVVQTASGDMQTYQIRTTPSATSLPQTMVMTSPVTLTSQTT-KTDDPQLKREIRLMKNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELKTLKDLYSHKSV-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P81269-1", "uniprot_id": "ATF1_MOUSE", "id": "P81269-1", "name": "Cyclic AMP-dependent transcription factor ATF-1", "aln": "MEDSHKSNTTETASQPGSTVAGPHVSQIVHQVSS----------------LSESEESQDSSDSIGSSQKAHG---------------------ILARRPSYRKILKDLSSEDTRGRKGEGENPSIS-AITSMSVPAPIYQTSSGQYIAIAPNGALQLAS-----------PSTDGVQALQTLTMTNSSSTQQG-----------TILQYAQTSDGQQILVPSNQVVVQTASGDMQTYQIRTTPSATSLPQTVVMTSPVTLASQTT-KTDDPQLRREIRLMKNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELKTLKDLYSHKSV-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P18846-1", "uniprot_id": "ATF1_HUMAN", "id": "P18846-1", "name": "Cyclic AMP-dependent transcription factor ATF-1", "aln": "MEDSHKSTTSETAPQPGSAVQGAHISHIAQQVSS----------------LSESEESQDSSDSIGSSQKAHG---------------------ILARRPSYRKILKDLSSEDTRGRKGDGENSGVSAAVTSMSVPTPIYQTSSGQYIAIAPNGALQLAS-----------PGTDGVQGLQTLTMTNSGSTQQGT----------TILQYAQTSDGQQILVPSNQVVVQTASGDMQTYQIRTTPSATSLPQTVVMTSPVTLTSQTT-KTDDPQLKREIRLMKNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELKTLKDLYSNKSV-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VWW0-3", "uniprot_id": "CREBB_DROME", "id": "Q9VWW0-3", "name": "Cyclic AMP response element-binding protein B", "aln": "MDNSIVEENGNSSAASGSNDVVDVVAQQAAAAVGGGGGGGGGGGGGNPQQQQQNPQSTTAGGPTGATNNAQGGGVSSVLTTTANCNIQYPIQTLAQHGLQVQSVIQANPSGVIQTAAGTQQQQQALAAATAMQKVVYVAKPPNSTVIHTTPGNAVQVRNKIPPTFPCKIKPEPNTQHPEDSDESLSDDDSQHHRSELTRRPSYNKIFTEISGPDMSGASLPMSDGVLNSQLAGTGAGGNAANSSLMQLDPTYYLSNRMSYNTNNSGIAEDQTRKREIRLQKNREAARECRRKKKEYIKCLENRVAVLENQNKALIEELKSLKELYCQTKND", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*::* . . :::. .** ::: . . . .:. :* :... *::::*:* : : . :.::: .* : * :: * *:*. . : :.... * :*..*:*: . * .: : :: ....:*: *: . .* . :* .: *::: .. : :..* .* * ::. :: ::.: ::* :***** ****************:***************:******:**:**.:.. ", "identical_positions": 73, "similar_positions": 103, "identity": "22.05%" }, { "cls_id": "homologset.agr.MGI:1298369", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8N7UY30-1", "uniprot_id": "A0A8N7UY30_DANRE", "id": "A0A8N7UY30-1", "name": "", "aln": "----MALTRTHVLRSWIFFSVFLCCWIFTNGQIVYSISEEANPGTAVGNLAKDFNLNVQDIERRGFQIVSESNKRYFDFNFKTGVLHVKERIDREELCEQKIKCSLPLEAIVNSPLNVFRFEINVLDINDNPPKFRTPKTTINISESALPGEQFALPSAFDADVGINSVKSYKLSPNEHFSLDVQSGGEQSVSAELVLQKALDREKQPLIRLTLTAVDGGKPLRSGTMQITVHVEDVNDNIPVFSKSLYKARVNENAPPGTSIITVQASDPDEGVNGQIVYALVNHD-NDRNVESFAINPETGEITVKGDVDYERKNAVELRVQAKDKGHKPRAALCKVLLEIIDVNDNVPEISVTSLVNTVKEDALIDTVVGMITVTDNDAGKNGQVILNIQGSSPFKVQNS-YKNYYTLFVNGPLDRERASEYNVTISAADEGTPPLSSTSVIAVHVSDVNDNAPRFPEPVINVYVKENSQIGAVLHTVSAVDPDVGDNARITYSLLE-SSKSGPVTSMININSDTGDLHSLQSFNYEEIKTFEFKVQATDSGVPPLSSNVTVNVFVLDENDNSPAILAPYSELGSVN-TENIPYSAEAGYFVAKIRAVDADSGYNALLSYHISEPKG--NNLFRIGTSSGEIRTKRRMSDNDLKTHPLVVLVCDNGEPSLSATVSIDAVVVESGGDVKTPFRHAP---VKEESFSDLNLYLLIAIVSVSVIFLLSLIGLIAVKCHR--TDSSLGRYSAPMITTHPDGSWSYSKSTQQYDVCFSSDTLKSDVVVFPAPFPPADAELISINGGDTFTRTQTLPNKEKPKVPSSDWRYSASLRAGMQSSVRMEESSVMQGAQGVLVQNWPTVSSA-PDNEGGEVSPPVGAGVDSNSWHFRYGPGPGGPPHLKPGEVPPEAFIIPGSPAIISIRQGQDGD--DKSDFITFGKKEEAKKLKKKKKKEKK-DKREKGKDDDD----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1N3Y6-1", "uniprot_id": "A0A8M1N3Y6_DANRE", "id": "A0A8M1N3Y6-1", "name": "", "aln": "----MAIVPLHNCLSVILFYVVFCFGSTAEGHIVYTVSEETNPGTTVGNLAKDLNLNLQDITNRGFQLVSGANKRYFELNSKTGFLHINDRIDRDELCGRSLKCSFPLEAIVNAPLNVYRFEVSIIDINDNSPTFRSPVKYFNISESAFPGERFPLPTAFDADVGSNSVKSYKLSANEHFSLDVQSGGEQSVSAELVLQKALDREKQPVIKLTLTAVDGGKPPRSGTINIIVNIEDVNDNIPVFSKPLFKTRVVENSPFGTSVIQVHASDPDEGPNSEIVYSLLSQD-NENNADAFAIDPETGVITVKGTVDYEKNAAVEIRVQAKDKGHKPRAAYCKVLVEITDINDNTPEISVTSLVNTVKEDAANGTVVSMITVLDNDAGKNGEIQLKIRDSLPFKVQNS-YKNYYTLIVNGHLDRETASEYNVTISAADEGTPPLSSTSVIAVHVSDVNDNAPRFPEPVINVYVKENSQIGAVLHTVSAVDPDVGDNARITYSLLE-SSKSGPVTSMININSDTGDLHSLQSFNYEEIKTFEFKVQATDSGVPPLSSNVTVNVFVLDENDNSPAILAPYSELGSVN-TENIPYSAEAGYFVAKIRAVDADSGYNALLSYHISEPKG--NNLFRIGTSSGEIRTKRRMSDNDLKTHPLVILVCDNGEPSLSATVSIDAVVVESGGDVKTPFRHAP---VKEESFSDLNLYLLIAIVSVSVIFLLSLISLIAVKCHR--TDSSLGRYSAPMITTHPDGSWSYSKSTQQYDVCFSSDTLKSDVVVFPAPFPPADAELISINGGDTFTRTQTLPNKEKPKVPSSDWRYSASLRAGMQSSVRMEESSVMQGAQGVLVQNWPTVSSA-PDNEGGEVSPPVGAGVDSNSWHFRYGPGPGGPPHLKPGEVPPEAFIIPGSPAIISIRQGQDGD--DKSDFITFGKKEEAKKLKKKKKKEKK-DKREKGKDDDD----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1N3N1-1", "uniprot_id": "A0A8M1N3N1_DANRE", "id": "A0A8M1N3N1-1", "name": "", "aln": "MGVNMDISEDRWSFYWICIVVFLTNWNYADGQIVYSVSEEVNTGTTVGNLAKDLNLNVQDLERRGFQIVSGPNKQYFDLHARNGILFVRERIDREELCGRSSKCALELEAIVSAPMSIYRFEVNILDVNDNAPTFRTSKLFLNISEQTYPGQRFTLPSAFDLDAGVNSVKSYKLSANEHFSLDVQSAGDQSVSAELVLQKALDREKQPVIRLTLTAVDGGKPPMSGTTQIIVNVVDVNDNIPVFDKPLYKARIAENSAIGASVITVSAKDADEGLNGEVIYSFINHD-NENSINAFLINPNTGEITVKGPLDYEENAAIEIRVQAEDKGQNPRASHCKVLIEIIDLNDNTPEISIMSLVNEVKEDSAPGTMVGLITVKDGDAGKNGVVRLQIRDSAQFRLENT-YKNRFSLVVNGPLDREVASEYNVTISAADEGTPPLSSTSVIAVHVSDVNDNAPRFPEPVINVYVKENSQIGAVLHTVSAVDPDVGDNARITYSLLE-SSKSGPVTSMININSDTGDLHSLQSFNYEEIKTFEFKVQATDSGVPPLSSNVTVNVFVLDENDNSPAILAPYSELGSVN-TENIPYSAEAGYFVAKIRAVDADSGYNALLSYHISEPKG--NNLFRIGTSSGEIRTKRRMSDNDLKTHPLVILVCDNGEPSLSATVSIDAVVVESGGDVKTPFRHAP---VKEESFSDLNLYLLIAIVSVSVIFLLSLISLIAVKCHR--TDSSLGRYSAPMITTHPDGSWSYSKSTQQYDVCFSSDTLKSDVVVFPAPFPPADAELISINGGDTFTRTQTLPNKEKPKVPSSDWRYSASLRAGMQSSVRMEESSVMQGAQGVLVQNWPTVSSA-PDNEGGEVSPPVGAGVDSNSWHFRYGPGPGGPPHLKPGEVPPEAFIIPGSPAIISIRQGQDGD--DKSDFITFGKKEEAKKLKKKKKKEKK-DKREKGKDDDD----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1N3N4-1", "uniprot_id": "A0A8M1N3N4_DANRE", "id": "A0A8M1N3N4-1", "name": "", "aln": "---MFSMHRRRSVVACFVLVVLVCFWDAASGQLSYSVSEEVSPGTTVGNLAKDLNLNVQELESRMFQIVTGAKKKYFEVNLKTGFLYVNERIDREELCAKAPKCTVSVEAVINNPLKLYQIEINIVDVNDNKPTFNSKTQYLDVAENTLPGVKFPLSYASDADVGKNTVSTYKLSQNEYFSLAVHKGEEQSVSAELVLQKALDREKQPLVQLTLTAADGGNPPKSGTSQIIIRVLDINDNAPVFSRPLYKASLVENVPIGSTVIIINATDKDEGTNSDIIYSLRETD-QDHILDIFQIDAITGAITVKGDVNFEKNNAFEIRAQASDKGQPPMSTHCKVLVEVLDINDNEPEITVTSLLSTVKEDASIGTAVALVSVIDRDGGRNGVVNCAVSNNVPFKLQTN-YKNYYSLVVDGPLDRERASEYNVTISAADEGSPPLSSTSVIAVHVSDVNDNAPRFPEPVINVYVKENSQIGAVLHTVSAVDPDVGDNARITYSLLE-SSKSGPVTSMININSDTGDLHSLQSFNYEEIKTFEFKVQATDSGVPPLSSNVTVNVFVLDENDNSPAILAPYSELGSVN-TENIPYSAEAGYFVAKIRAVDADSGYNALLSYHISEPKG--NNLFRIGTSSGEIRTKRRMSDNDLKTHPLVILVCDNGEPSLSATVSIDAVVVESGGDVKTPFRHAP---VKEESFSDLNLYLLIAIVSVSVIFLLSLISLIAVKCHR--TDSSLGRYSAPMITTHPDGSWSYSKSTQQYDVCFSSDTLKSDVVVFPAPFPPADAELISINGGDTFTRTQTLPNKEKPKVPSSDWRYSASLRAGMQSSVRMEESSVMQGAQGVLVQNWPTVSSA-PDNEGGEVSPPVGAGVDSNSWHFRYGPGPGGPPHLKPGEVPPEAFIIPGSPAIISIRQGQDGD--DKSDFITFGKKEEAKKLKKKKKKEKK-DKREKGKDDDD----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1N3Y1-1", "uniprot_id": "A0A8M1N3Y1_DANRE", "id": "A0A8M1N3Y1-1", "name": "", "aln": "------MAHIIVMSGIVICLVLLLLMPSASAQVAYSISEEANTGTFVGNIAKDLNLNIQELESRGFHIPAVSGRKYFEVNLKTGVLFVSERIDREAFCPASPQCSVNLEAIVNNPLNLFRIEINIVDINDNSPSFRVRSMHINVSEYAFIGDRFQLPRASDPDVGANSVKSYKLSPNEHFSLDVQSGGEQSASAELVLQKALDREKQPAIHLTLTAVDGGKPPKSGTMQIAIHVQDVNDNAPVFGKALYKVRIVENAPLGTLVINLNATDLDEGLNSEIIYSLVQQDSDDKASSVFKIDSATGVVSMQGRVDFEERNAYEIHAQAKDKGASPRSAHCKILVEVLDVNDNEPEISLTSQVNTVREDAKRETTVALITISDKDSGKNGNVHGKVVGDVPFKLQSS-YKNYYSLVVDEPLDRERVDRYNVTIMASDEGAPPLSATRVFTVYVSDVNDNPPSFPNPVINVFVKENGPMDQIIYTLSAVDPDLNENSKITYGLLEPLHKSGSTYSAITINSDTGDLHSLQSFNYEEIKTFEFKVQATDSGVPPLSSNVTVNVFVLDENDNSPAILAPYSELGSVN-TENIPYSAEAGYFVAKIRAVDADSGYNALLSYHISEPKG--NNLFRIGTSSGEIRTKRRMSDNDLKTHPLVILVCDNGEPSLSATVSIDAVVVESGGDVKTPFRHAP---VKEESFSDLNLYLLIAIVSVSVIFLLSLISLIAVKCHR--TDSSLGRYSAPMITTHPDGSWSYSKSTQQYDVCFSSDTLKSDVVVFPAPFPPADAELISINGGDTFTRTQTLPNKEKPKVPSSDWRYSASLRAGMQSSVRMEESSVMQGAQGVLVQNWPTVSSA-PDNEGGEVSPPVGAGVDSNSWHFRYGPGPGGPPHLKPGEVPPEAFIIPGSPAIISIRQGQDGD--DKSDFITFGKKEEAKKLKKKKKKEKK-DKREKGKDDDD----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1N3X5-1", "uniprot_id": "A0A8M1N3X5_DANRE", "id": "A0A8M1N3X5-1", "name": "", "aln": "---MANENTRTWMSRIFYLMCLLFNSGGKAAQINYSLQEESKIGVNVGNIAKDLGIDPTSLENRNFRIVVGTKQELFRVNHEDGALFVSQRIDREELCAKINPCLINLKAVIENPLEMHQISVDIIDVNDNPPSFLDENYKLEILESAMTGARFQVETAHDPDIGSNDLQSYKLSQNHYFRLETEDMGDEGKIPVLILQKPLDREKSARHNLILTATDGGKPHKSAAANITIVVSDVNDNTPVCDKQKYTVTVKEDAPEGTFLLRVNASDSDEGVNGEIEYSLRNKF-RKGASDVFDLDNITGELKIKGGLNFEERQVYELKILAADKGAVSLSTQCNVLVNVEDVNDNRPEIDVTSLSSHIPEDAAPGTVVALIGVTDLDSGMNGKIICSLPKNIPFDLKPSPDGNFYSLVTKENIDKEAKSSYDITITAKDLGSPSLSSTRSIHVEVTDVNDNSPKFAQSPYTFYVTENNKPGIAVFSLSASDLDEGENARVSYTIDR-INSDQSMTSFLSINEANGTVYSLKSFDFESLKTFHFFVVAKDSGSPSLSSNVTVNVFILDQNDNVPVILYPVSANGSAEGVEEIPRNVNAGHLVTKVRAYDADIGYNGWLLFSLQEVSE--HSLFALDRYTGQIRTLRSFTETDEAQHKLVILVKDNGNVSLSATATVIVKVVEPKEAFAASDVKNA---VKDKEENNVTFYLIITLGSVSVLFVISIIVLIVMQCSK--STDYSSKY---LQDTNYDGTLCHSIQYRSGDKRYMLVGPRMSIGSTIAPGS---------NRNTLVIPDRRRRDSGEPKVPSSDWRYSASLRAGMQSSVRMEESSVMQGAQGVLVQNWPTVSSA-PDNEGGEVSPPVGAGVDSNSWHFRYGPGPGGPPHLKPGEVPPEAFIIPGSPAIISIRQGQDGD--DKSDFITFGKKEEAKKLKKKKKKEKK-DKREKGKDDDD----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9UN72-1", "uniprot_id": "PCDA7_HUMAN", "id": "Q9UN72-1", "name": "Protocadherin alpha-7", "aln": "--MVCPNGYDPGGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAVCKFRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDINDNPPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDV-SPDIKSKFHMDPLSGAITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVITLISVFDRDFGVNGQVTCSLTPRVPFKLVST-FKNYYSLVLDSALDRESVSAYELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNALVSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWLSYELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLVSLVESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPSSEGACSLVKPTLVCSSAVGSWSFSQQRRQ-RVCSGEGPPKTDLMAFSPSLPQGPS-----STD-------------NPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPG--NPKQSGPGELP-DKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Y5H5-1", "uniprot_id": "PCDA9_HUMAN", "id": "Q9Y5H5-1", "name": "Protocadherin alpha-9", "aln": "--MLYSSRGDPEGQPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELVPRLFQLDSKGRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDINDNPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDV-SPDIKSKFHMDPLSGAITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVKEDAQLGTVIALISVIDLDADANGQVTCSLTPHVPFKLVST-YKNYYSLVLDRALDRESVSAYELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDADSGYNAWLSYELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALTATATVLVSLVESGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTVLRCSAMPTEGECAPGKPTLVCSSAVGSWSYSQQRRQ-RVCSGEGKQKTDLMAFSPGLSPCAG-----STERTGEPSASSDSTGKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPG--NPKQSGPGELP-DKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q91Y13-1", "uniprot_id": "PCDA7_MOUSE", "id": "Q91Y13-1", "name": "Protocadherin alpha-7", "aln": "--MVNLRGYNWKSQQLLLFLIIVAAWEAGSGQLHYSVPEEAKHGTFVGRIAQDLGLELTELVPRLFRVASKDRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVEVKDINDNPPMFPATQKALFILESRLLDSRFPLEGASDADVGSNALLTYRLSTNEHFSLDVPPNHEQVKPLGLVLRKPLDREEAAEIRLLLTATDGGKPELTGTVQLLITVLDVNDNAPVFDRSLYTVKLPENVPNGTLVIKVNASDLDEGVNGDVMYSFSSDV-SSDIKSKFHMDTVSGEITVIGIIDFEESKAYKIPLEARDKGFPQLPGHCTILVEVVDANDNAPQLTVSSLSLPVSEDSQPGRVVTLISVFDRDSGANGQVTCSLTPHIPFKLVST-FKNYYSLVLDSALDRETIANYDVIVTARDGGSPSLWATASVSVEVADVNDNAPLFAQPEYTVFVKENNPPGAHIFTVSAMDADAQENALVSYSLVERRVGERLLSSYVSVHAESGKVFALQPLDHEELELLQFQVSARDAGVPALGSNVTLQVFVLDENDNAPTLLGPLANGVGGTMNEVVSRALVPGQVVAKVRAVDEDSGYNAWLSFELQPVAGGVRSPFRVGLYTGEISTTRALEETDALRQCLLVLVKDHGEPSLTATATVLLSLVDSGQTQKVSSKVSAGASRVDQRLVDVNVYLIIAICAVSSLLVLTLLLYTALRCSATPTDGACAPGKPMLVCSSAVGSWSYSQQRRQ-RVCSGEGPPKTDLMAFSPSLPQGPS-----STD-------------NPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPG--NPKQSGPGELP-DKFIIPGSPAIISIRQEPANNQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .. .:: *:: ** . * **.:*:*:.:: .: * *: : .: . * *.: .****: :* * . ::.::. *:.:.:..:.: *:*** * * : : * . :* : * * * * * : :*:** *.:* * . :: *:*:* ****: . .* ***.***:* :.: :: : : * *** ** .: :.. : *: . *: :: *.* *** *.:: *:: . . * :: :* :.: * :::*. . :: * *** . *.:*::: * *** *:: : : : **: : :: : * * . ** : : * : . * ::*. . :*:* *:: : * * *:*.* :* . * *:*****.* *.:. ..:*.**. . :.::** * * .*: ::* : . . * :.:: .* :.:*:.::.*.:: :.* * * *:* *.*.****::**:**:*** *.:* * . * : .* .* *:** * * ***. * : :. * :. :*:* * * : :.* : *::** *:*: :*:**.:: :*:. . : ::..**:*:: :** ::::::: .::* : . . : : *: ..* . :. : .: . . . :*: *..************:***::**:.:::.. * *:******* *: *.***********:**** *:**** .* : ***:* : ************** .. *************:** ***** :*. :*:***:. * ", "identical_positions": 274, "similar_positions": 286, "identity": "28.45%" }, { "cls_id": "homologset.agr.MGI:1298373", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P17077-1", "uniprot_id": "RL9_RAT", "id": "P17077-1", "name": "Large ribosomal subunit protein uL6", "aln": "MKTILSNQTVDIPENVDITLKGRTVIVKGPRGTLRRDFNHINVELSLLGKKKKRLRVDKWWGNRKELATVRTICSHVQNMIKGVTLGFRYKMRSVYAHFPINVVIQENG--SLVEIRNFLGEKYIRRVRMRTGVACSVSQAQKDELILEGNDIELVSNSAALIQQATTVKNKDIRKFLDGIYVSEKGTVQQPDE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0LYU5-1", "uniprot_id": "A0ABK0LYU5_RAT", "id": "A0ABK0LYU5-1", "name": "Large ribosomal subunit protein uL6", "aln": "MKTILSNQTVDIPENVDITLKGRTVIVKGPRGTLRRDFNHINVELSLLGKKKKRLRVDKWWGNRKELATVRTICSHVQNMIKGVTLGFRYKMRSVYAHFPINVVIQENG--SLVEIRNFLGEKYIRRVRMRT--------AQKDELILEGNDIELVSNSAALIQQATTVKNKDIRKFLDGIYVSEKGTVQQPDE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P32969-1", "uniprot_id": "RL9_HUMAN", "id": "P32969-1", "name": "Large ribosomal subunit protein uL6", "aln": "MKTILSNQTVDIPENVDITLKGRTVIVKGPRGTLRRDFNHINVELSLLGKKKKRLRVDKWWGNRKELATVRTICSHVQNMIKGVTLGFRYKMRSVYAHFPINVVIQENG--SLVEIRNFLGEKYIRRVRMRPGVACSVSQAQKDELILEGNDIELVSNSAALIQQATTVKNKDIRKFLDGIYVSEKGTVQQADE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P51410-1", "uniprot_id": "RL9_MOUSE", "id": "P51410-1", "name": "Large ribosomal subunit protein uL6", "aln": "MKTILSNQTVDIPENVEITLKGRTVIVKGPRGTLRRDFNHINVELSLLGKKKKRLRVDKWWGNRKELATVRTICSHVQNMIKGVTLGFRYKMRSVYAHFPINVVIQENG--SLVEIRNFLGEKYIRRVRMRTGVACSVSQAQKDELILEGNDIELVSNSAALIQQATTVKNKDIRKFLDGIYVSEKGTVQQADE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P50882-1", "uniprot_id": "RL9_DROME", "id": "P50882-1", "name": "Large ribosomal subunit protein uL6", "aln": "MRTINSNQCVKIPKDIKASVKARVVTITGTRGTLKRSFKHLALDMYMP--DKRTLKVEKWFGTKKELAAVRTVCSHIENMIKGVTFGFQYKMRAVYAHFPINCVTSENN--TVIEIRNFLGEKYIRRVEMAPGVTVVNSTAQKDELIVEGNDIESVSGSAALIQQSTTVKNKDIRKFLDGLYVSEKTTVVKLES", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P05738-1", "uniprot_id": "RL9A_YEAST", "id": "P05738-1", "name": "Large ribosomal subunit protein uL6A", "aln": "MKYIQTEQQIEVPEGVTVSIKSRIVKVVGPRGTLTKNLKHIDVTFTKV--NNQLIKVAVHNGGRKHVAALRTVKSLVDNMITGVTKGYKYKMRYVYAHFPINVNIVEKDGAKFIEVRNFLGDKKIRNVPVRDGVTIEFSTNVKDEIVLSGNSVEDVSQNAADLQQICRVRNKDIRKFLDGIYVSHKGFITEDL-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P51401-1", "uniprot_id": "RL9B_YEAST", "id": "P51401-1", "name": "Large ribosomal subunit protein uL6B", "aln": "MKYIQTEQQIEIPEGVTVSIKSRIVKVVGPRGTLTKNLKHIDVTFTKV--NNQLIKVAVHNGDRKHVAALRTVKSLVDNMITGVTKGYKYKMRYVYAHFPINVNIVEKDGAKFIEVRNFLGDKKIRNVPVRDGVTIEFSTNVKDEIVLSGNSVEDVSQNAADLQQICRVRNKDIRKFLDGIYVSHKGFIVEDM-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: * ::* :.:*:.: ::*.* * : *.**** :.::*: : : .:: ::* * :*.:*::**: * ::***.*** *::**** ******** *:. ..:*:*****:* **.* : ***:::.**.:* ** .** :** *:**********:***.* : : ", "identical_positions": 77, "similar_positions": 59, "identity": "39.69%" }, { "cls_id": "homologset.agr.MGI:1298375", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88480-1", "uniprot_id": "CABIN_RAT", "id": "O88480-1", "name": "Calcineurin-binding protein cabin-1", "aln": "MIRIAALNASSTIEDDHEGSFKSHK-IQTKEAQEAEAFALYHKALDLQKHDRFEESAKAYHELLEARLLREAVSSGDEKEGLKHPGLILKYSTYKNLAQLAAQREDLETAMEFYLEAVMLDSTDVNLWYKIGHVALRLIRLPLARHAFEEGLRCNPDHWPCLDNLITVLYTLSDYTTCLYFICKALEKDCRYSKGLVLKEKIFEEQPCLRKDSLRMFLKCDMSVHEVSVNAAETQAIVDEALGLRKKRQALIVREKEPDLKLVQPIPFFTWKCLGESLLAMYNHLTTCEPPRPSLGKRIDLSDYQDPSQLLAPSIVVTPVSVVQPSPVCTNPTVAVAEP-----VLSYTSVTTTSFPLHSPGLLDTGTPMG--------------------------DVSG-----GDKSKKGVKRKKTLEESGETAKRRSARVRNTKCKKEEKVDFQGLLVKFLPSRLRKLDPEEEDDPFNNYEVQSEAKLESFSNVGPHRLSFDSATFMESEKQDVHAFLMENLTNGGVLELMMRYLKSMGHKFLLKWPPGLAEVVLSVYHSWRRHSTSLPNPLLRDCSNKHIKDMMLMSLSCMELQLDQWLLTKGRSSTVSPRNCPAGVVTGRFGPDFPGTHCLGDLLQLSFASSQRDLFEDGWLEFVVRVYWLKARFLALQGDMEQALENYDICTEILQSSTALQAQAGAEQRDIVIRLPNLHNDSIVSLEEIDKNLKSLERCQSLEEIQRLFEAGDYKAVVQLLRPTLCT-SGFDRAKHLEFMTSIPERPAQLLLLQDSLLRLEEHRQCFECSDVALNEAVQQMLNSSDS--AAKEEWAATVTQLLLGMEQALSSDSRGSILKESSSPTGLVRLTNNLIQVIDCSMAVQEEPKEPYVSSVLPWIILHRIIWQEEDTFRSLCHQQQLQNPTEEGISEMPMLPSSLMLLNTAHEYLGRRSWCCNSDGALLRFYVHVLQKELAASASEDTHPYKEELETALEQCFYCLYSFPSKKSKARYLEEHSAQQVDLTWEDALFMFEYFKPKTLPEFDSYKTSTVSADLANLLKRIATIVPRTEKPALSMDKVSAYIEGTSAEVPCLPDGADPAPPVLNELYYLLADYHFKNKEQSKAIKFYMHDICICPNRFDSWAGMALARASRIQDKLNSNELKSDGPIWRHATPVLNCFRRALEIDSSNLSLWIEYGTMSYALHSFASRQLKQWRAELPPEVVQQMEDRRDSMLETARHCFTSAAHCEGDGDEEEWLIHYMLGKVAEKQQQPPTVYLLHYRQAGHYLHEEAARYPKKIHYHNPPELAMEALEVYFRLHASILKLLGKPDSG--------VSAEVLVSFMKEAAEGPFARGEEKNTPKAS-EKEKACLVD-EDSHSSAGTLPGP------------GASLPSSSGPGLTSPPYTATPIDHDYVKCKKPRQQATPDDRSQ----------------------------------DSTAVALSDSSSTQDFFNEPTSLLDGSRKLLPEKRISGLSAQAGPSGKDLPGPTEERG-------------------KTEESLESTEAFRVVEPSVQKP--------VADSSASAYIPSKPAVSTPPPWDGKKRSDPLG--EPVAFPQGLPAGAEEQRQFLTEQCIASFCLCLSRFPQHYKSLYRLAFLYTYSKTHRNLQWARDVLLGSSIPWQQLQHMPAQGLFCERNKTNFFNGIWRIPVDEIDRPGSFAWHMNRSIVLLLKVLAQLRDHSTLLKVSSMLQRTPDQGKKYLRDADRQVLAQRAFILTVKVLEDTLSELAEGLEHPGSKACGLSGARMTTDVSHKASPEDGQESLP--HPKKLPLADGSGPGPEPGGKVGPLH---QLPVATDTRDNTEQGGEPKDKERPPVGPTEPMDTGETAARHPDLEPTPRLLPGRPPRDRGPES-RSAELSLEELSISTRQQP---APLVPSPVTP-TTAAPTTMGARAAGHPEEAPPRPNRKRKLLQDTESGKTLLLDAYRVWQQGQKAMAYDLSRIEKIMSETYMLIKQVDEETALEQAVKFCQVHLGAAAQRQASGDAPTTPKHPKDSRENFFPATVAPSAPDTTAPDALQRPSDSHLKP-----GLAAAITCPPSASASTP----DPGIPQPHRPEAVPSRAPLSPDGEEVSGVTEGPSFLSQEPRHSHQMKMAATGPLAEQHCWPVEAACQTGAEPTFSQ-----------------------------ATSTKVPSSGSTQTPESHQGKTESSRAKSRLLPNMPKLVIPSATTKFPPEITVTPPTPTLLSPKGSISEETKQKLKSAILSAQSAANVRKESLCQPALEVLETSSQESSLESETDEDDDFMDV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "G3X8Q1-1", "uniprot_id": "G3X8Q1_MOUSE", "id": "G3X8Q1-1", "name": "Calcineurin-binding protein cabin-1", "aln": "MIRIAALNASSTIEDDHEGSFKSHK-IQTKEAQEAEAFALYHKALDLQKHDRFEESAKAYHELLEARLLREAVSSGDEKEGLKHPGLILKYSTYKNLAQLAAQREDLETAMEFYLEAVMLDSTDVNLWYKIGHVALRLIRLPLARHAFEEGLRCNPDHWPCLDNLITVLYTLSDYTTCLYFICKALEKDCRYSKGLVLKEKIFEEQPCLRKDSLRMFLKCDMSIHDVSVSAAETQAIVDEALGLRKKRQALIVREKEPDLKLVQPIPFFTWKCLGESLLAMYSHLTTCEPPRPSLGKRIDLSDYQDPSQLLASSVVVTPVSVVQPSPICTNPTVAVAEP-----VLSYTSVTAASFPLHSPSLLDTGTPMG--------------------------DVSG-----GDKSKKGVKRKKTVEESGETAKRRSARVRNTKCKKEEKVDFQGLLVKFLPSRLRKLDPEEEDDPFNNYEVQAEAKLESFSNVGPHRLSFDSATFMESEKQDVHAFLMENLTNGGLLELMMRYLKSMGHKFLLKWPPGLADVVLSVYHSWRRHSTSLPNPLLRDCSNKHIKDMMLMSLSCMELQLDQWLLTKGRSSAVSPRNCPAGVVTGRFGPDFPGTHCLGDLLQLSFASSQRDLFEDGWLEFVVRVYWLKARFLALQGDMEQALENYDICTEILQSSSAIQAQAGAEQGDIVIRLPNLHNDSVVSLEEIDKNLKSLERCQSLEEIQRLFEAGDYKAVVHLLRPTLCT-SGFDRAKHLEFMTSIPERPAQLLLLQDSLLRLKDHRQCFECSDVALNEAVQQMLNSSES--AAKEEWVATVTQLLLGIEQALSSDSSGSILKESSSTTGLVRLTNNLIQVIDCSMAVQEEPKEPYVSSVLPWIILHRIIWQEEDTFRSLCHQQQLQNPTEEGIPEMPMLPSSLMLLNTAHEYLGRRSWCCNSDGALLRFYVQVLQKELAASASEDTHPYKEELETALEQCFYCLYSFPSKKSKARYLEEHSAQQVDLIWEDALFMFEYFKPKTLPEFDSYKTSTVSADLANLLKRIATIVPRTEKPALSMDKVSAYIEGTSAEAPCLPEGADPTPPVLNELYYLLADYHFKNKEQSKAIKFYMHDICICPNRFDSWAGMALARASRIQDKLNSNELKSDGPIWKHATPVLNCFRRALEIDSSNLSLWIEYGTMSYALHSFASRQLKQWRSELPPELVQQMEDRRDSMLETARHCFTSAARCEGDGDEEEWLIHYMLGKVAEKQQQPPTVYLLHYRQAGHYLHEEAARYPKKIHYHNPPELAMEALEVYFRLHASILKLLGKPDSG--------VGAEVLVSFMKEAAEGPFARGEEKNTPKAS-EKEKACLVD-EDSHSSAGTLPGP------------GASLPSSSGPGLTSPPYTATPIDHDYVKCKKPHQQAAPDDRSQ----------------------------------DSTAVALSDSSSTQDFFNEPTSLLEGSRKLFPEKRLSGLSAQAGPSGKDLPGPTEERG-------------------KTEESLESTEAFRVVEQSVQKP--------VADSSASAYIPSKPPASTPPLWDGKKRGDSLG--EPVAFPQGLPAGAEEQRQFLTEQCISSFCLCLSRFPQHYKSLYRLAFLYTYSKTHRNLQWARDVLLGSSIPWQQLQHMPAQGLFCERNKTNFFNGIWRIPVDEIDRPGSFAWHMNRSIVLLLKVLAQLRDHSTLLKVSSMLQRTPDQGKKYLRDADRQVLAQRAFILTVKVLEDTLSELAEGSEHPGSKACGLSGARMTTDVSHKASPEDGQESPQ--HPKKLPLADGSGPGPEPGGRMGPLN---QLPVVTDIRDNTDQGGEQKDKESPQVGPTEPMDTSEAAGRHSDLEQTSRLLPGRPPRDRGPES-RSAELSLEELSISTRQQP---APLAPSPAAPTTTAAPTTMAARGAGHSEEAPPRPNRKRKLLEDTESGKTLLLDAYRVWQQGQKGMAYDLSRIEKIMSETYMLIKQVDEETALEQAVKFCQVHLGAATQRQASGDTPTTPKHPKDSRENFFPATVVPTVPDPTAPDALQRPSDSHLKP-----VLATVITCPPSASASIPDLSTDPGIPRPHRPETTPSRAPLSPEGEEASGVTEGTSILPQEPRYSHQIKMAATGHLAEQHCWPVEVACQTGAEPTCSQ-----------------------------ASSTKVPSSGSTQTAESHQGKTESSRAKSRLLPNMPKLVIPSATTKSPPEITVTPPTPTLLSPKGSISEETKQKLKSAILSAQSAANVRKESLCQPALEVLETSSQESSLESETDEDDDFMDV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y6J0-1", "uniprot_id": "CABIN_HUMAN", "id": "Q9Y6J0-1", "name": "Calcineurin-binding protein cabin-1", "aln": "MIRIAALNASSTIEDDHEGSFKSHK-TQTKEAQEAEAFALYHKALDLQKHDRFEESAKAYHELLEASLLREAVSSGDEKEGLKHPGLILKYSTYKNLAQLAAQREDLETAMEFYLEAVMLDSTDVNLWYKIGHVALRLIRIPLARHAFEEGLRCNPDHWPCLDNLITVLYTLSDYTTCLYFICKALEKDCRYSKGLVLKEKIFEEQPCLRKDSLRMFLKCDMSIHDVSVSAAETQAIVDEALGLRKKRQALIVREKEPDLKLVQPIPFFTWKCLGESLLAMYNHLTTCEPPRPSLGKRIDLSDYQDPSQPLESSMVVTPVNVIQPSTVSTNPAVAVAEP-----VVSYTSVATTSFPLHSPGLLETGAPVG--------------------------DISG-----GDKSKKGVKRKKISEESGETAKRRSARVRNTKCKKEEKVDFQELLMKFLPSRLRKLDPEEEDDSFNNYEVQSEAKLESFPSIGPQRLSFDSATFMESEKQDVHEFLLENLTNGGILELMMRYLKAMGHKFLVRWPPGLAEVVLSVYHSWRRHSTSLPNPLLRDCSNKHIKDMMLMSLSCMELQLDQWLLTKGRSSAVSPRNCPAGMVNGRFGPDFPGTHCLGDLLQLSFASSQRDLFEDGWLEFVVRVYWLKARFLALQGDMEQALENYDICTEMLQSSTAIQVEAGAERRDIVIRLPNLHNDSVVSLEEIDKNLKSLERCQSLEEIQRLYEAGDYKAVVHLLRPTLCT-SGFDRAKHLEFMTSIPERPAQLLLLQDSLLRLKDYRQCFECSDVALNEAVQQMVNSGEA--AAKEEWVATVTQLLMGIEQALSADSSGSILKVSSSTTGLVRLTNNLIQVIDCSMAVQEEAKEPHVSSVLPWIILHRIIWQEEDTFHSLCHQQQLQNPAEEGMSETPMLPSSLMLLNTAHEYLGRRSWCCNSDGALLRFYVRVLQKELAASTSEDTHPYKEELETALEQCFYCLYSFPSKKSKARYLEEHSAQQVDLIWEDALFMFEYFKPKTLPEFDSYKTSTVSADLANLLKRIATIVPRTERPALSLDKVSAYIEGTSTEVPCLPEGADPSPPVVNELYYLLADYHFKNKEQSKAIKFYMHDICICPNRFDSWAGMALARASRIQDKLNSNELKSDGPIWKHATPVLNCFRRALEIDSSNLSLWIEYGTMSYALHSFASRQLKQWRGELPPELVQQMEGRRDSMLETAKHCFTSAARCEGDGDEEEWLIHYMLGKVAEKQQQPPTVYLLHYRQAGHYLHEEAARYPKKIHYHNPPELAMEALEVYFRLHASILKLLGKPDSG--------VGAEVLVNFMKEAAEGPFARGEEKNTPKAS-EKEKACLVD-EDSHSSAGTLPGP------------GASLPSSSGPGLTSPPYTATPIDHDYVKCKKPHQQATPDDRSQ----------------------------------DSTAVALSDSSSTQDFFNEPTSLLEGSRKSYTEKRLPILSSQAGATGKDLQGATEERG-------------------KNEESLESTEGFRAAEQGVQKP--------AAETPASACIPGKPSASTPTLWDGKKRGDLPG--EPVAFPQGLPAGAEEQRQFLTEQCIASFRLCLSRFPQHYKSLYRLAFLYTYSKTHRNLQWARDVLLGSSIPWQQLQHMPAQGLFCERNKTNFFNGIWRIPVDEIDRPGSFAWHMNRSIVLLLKVLAQLRDHSTLLKVSSMLQRTPDQGKKYLRDADRQVLAQRAFILTVKVLEDTLSELAEGSERPGPKVCGLPGARMTTDVSHKASPEDGQEGLP--QPKKPPLADGSGPGPEPGGKVGLLN---HRPVAMDAGDSADQSGERKDKESPRAGPTEPMDTSEATVCHSDLERTPPLLPGRPARDRGPES-RPTELSLEELSISARQQP---TPLTPAQPAP-APAPATTTGTRAGGHPEEPLSRLSRKRKLLEDTESGKTLLLDAYRVWQQGQKGVAYDLGRVERIMSETYMLIKQVDEEAALEQAVKFCQVHLGAAAQRQASGDTPTTPKHPKDSRENFFPVTVVPTAPDPVPADSVQRPSDAHTKPRPALAAATTIITCPPSASASTLDQSKDPGPPRPHRPEATPSMASLGPEGEELARVAEGTSFPPQEPRHSPQVKMAPTSSPAEPHCWPAEAALGTGAEPTCSQEGKLRPEPRRDGEAQEAASETQPLSSPPTAASSKAPSSGSAQPPEGHPGKPEPSRAKSRPLPNMPKLVIPSAATKFPPEITVTPPTPTLLSPKGSISEETKQKLKSAILSAQSAANVRKESLCQPALEVLETSSQESSLESETDEDDDYMDI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B598-1", "uniprot_id": "A0A8M3B598_DANRE", "id": "A0A8M3B598-1", "name": "", "aln": "MIRIAALNAASQAADEHEDAFRSTKPGQTKEAQEAEAFALYHKALDLQKHDKFDESAKAYHELLKTPLLKEAVASEDEKVGLKHPGLMLKYSTYKNLASLAVLKDDLDTAMDFYVQAVMLDSTDVNMWYKMGKLALRKVSMPLARHAFEVGLHCNPEHWPCLDSLITVLYALSDYSCCLYYICKALEKDSGYSKGRVLKEKIFQEQPCLRRDSMKMFSKLDISLQYVDVDEEEAHSIVEEALELRRQRQAKLTRHPVADLQLVQPIKYFTWKSVGESFLAMYKHQNACLVPRPDFGRRIDLSMYRDPDCLLQMPISAPVPAAAAAPSDPPQPTVPISDPPAPVVLPPAPSSPSASLPPCPELLLQAITVAGGVPLNQNVIEITTTTTVTTTAASAVEDTAGNSAALDDKVKKGTKRKRVIEDTVETAKRRSARVRNTKCKKEEKIDFQELLLKFLPSRLKKFEDDEDEESLSNMDSQCGIKPDSQLNHGSN--SSNYIVSMESERSEVHAFLMANMQNGGILELMIYYLKAVGQKFLEEWPAGLSGVVLDLFNCWRKHSAGLPNPLLRDSSNKHIKEMMLMSLGCLELQLEQKSMMKGKNASQRKTMSASGRDCG--DLDSPETRFQADLFLLTMASSQRDLFEDHWLSFAIRVHWLKARHLAFQGDMEEALECYDMCVGLLKG-------QTSENDKIAIHLPNLSVDNSISIEEIEKKLKSLERCQSLEEIQKLFDAGDYQSVVRLLQPTLSFGHGAARLKPLDYISSAPERPAQLLLLQSSLLRQKDFSSCLETTEVSLNEALQHLNSALPSSPSAKEEWISTITALLKGIESCITDKP--ELLRQTPRSANLPRLANNLIQLIATSMVLPDDPKEAHFSSLLPWILLYHLIKQEEAAFDCMLRQHIADEEDEE--DDTPLLPSSLMLLNTAHECLGRRSWCCNSDGALLKFFMRVLREKLSG---HENLPYKEDLEMALEQCFFCLYAYPSKKSKARYLEEHSAPQVELHWKEAVFMFEYFKPKTMPEFDSYKTSTVSADLANLLKRLSGIIPRTDGPTLSIDDVSAYIEGGAVKVPALPEGASPAPPVVNELYYLLADYHFKNKEQSKAIKFYMHDICMSPNRFDSWAGMALARASRIQDKLNSNELRSDGPIWKNSLAVLTCFRRALEIDGSNLSLWIEYGTMSYALHSFASRQLKQWGHQLPADLTKQMEERRDSMLETASQCFQSASRCDGD--EEEWLIHYMLAKIAEKRKQPPKDYLQMYKKSAHYLHEEAARYPRKIHYHNPPDLAMEALELFFRLSATILKLLENVENTGEQAETKLLDYDLFFCLLTEAAVGPFARGEEKTAPKTSSDKEKLLSVNDEDSLSSAGVMTCPAAMTGSASVAAAGASLAGDGAAGASSPPYAVTPLDHDYAKRKNLQQRHRQGEQIQRQQQRQQQDADFSLDHDYCVCVSALRPGSVYEQSQDSVAGLSDSSSLQDVFMDATSSQDSSHKLHPVK-CSIFPEDSNATGKEKQATVEDTGPLEDKNMDFSSATLSQESSVTQESSDTTLSITSPEASVPKTPTADPLSQAPSVPQPPTTPNRPHPQTGPSSESKRRPEPPPPLEAMELPKALPAGREEQRKTLVDVCVRCLFLCLSRYPQHYKSLYRLAHLYAYSNTHKNLQWARDVLLGSSVPWQQLKHMPAQGLFCERNKTNLFNGIWRIPVDEIDRPGSFASHMNRSIVLLLHVLSQLKDHHTLLKISLMLQRTPDQGKKYLRDVDRQALAKRAFFFTVKVLEDNLDKLTGTSDPPKPSATGMG-EMTTTDVSNRPPAAEDPKSSQSSQPKTAVPETPTATGGESGLPSFPQKCSATLQLSLEPLPQATASTLQATSEPMELGSGSWLSSSKFKDPHVDAGSQEIVKSAAEETEKLPESSRASELSLEELSISTKQQQQQQQQIQNQVNAAKPATTPITPTPLPSGADLVVPQRPSRKRKLLDDVESGKTLLLDAYRVWQQGQKGMTYDLQRIEKIMSETYMLIKQVDEDVALDQAVKFCQIQMATSAQRQSSSEAPSTPKFTKEQRDIFFPASFSTPCLHTHTHPASVQDAEARLSKT----PRPLLIQTQTHSTPAQIYCQTDQSQQRKTTSQPIASMAFLPHTEDREEPVSEGLLYRQQESHLCQQMKMATVSQIHNTHEWAAHEP------PSCST-------------------------------------HSSTESEQSKQN--DPSRIRSRIPPNMPKLLIPSTVTKFPPEITVTPPTPTLLSPKGSISEETKQKLKNVILSSQSAANVKKDTLAQPALEVQETSSQESSLESESDEEDDYMDI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*********:* *:**.:*:* * ************************:*:**********:: **:***:* *** *******:**********.**. ::**:***:**::**********:***:*::*** : :******** **:***:******.******:****: ***:********. **** *******:******:**::** * *:*:: *.*. *:::**:*** **::*** :.*. .**:***** :****.:***:****.* .:* ***.:*:***** *:**. * .: .. . ... .:*:*.:::* : . .* .::*:* . **:: : * * :* .** ***.***: *:: ********************:*** **:*******:*:: :*:::.:.* : *. * :* . *.: * : . ****:.:** **: *: ***:****: ***::*:*** .**.**: ***.:::.**:**:.********.******:******.*:****:* : **:.:: ..:* * . * * *: .**: *::********** **.*.:**:*****.**:*****:*** **:*. :*:. :*. .*.*:**** *. :*:***:*:**************:*::****::**:**:***. * * * *::::* ***********.**** ::. .*:* ::*:****:*:: .: : :***** :*:* ** *:*..:: .. .:*: :. .:.* **:*****:* **.: ::.**.:.**:****:*:::* *** :* .: :*: :: ** : *:************* ***************:*:::**:::*:. .:. ****:** ******:***::*************** **:* *::*:**********:*********************:: *:***: *:**:*.******* :.:.*.**:**.*:***:*****************************:.***************************:******::: .**.*********.*************************** :**.::.:*** ********* :** **::*:** **********.*:***::***. ** *:::.***********:********:*******::*** *:***** : :. :. :::. ::.*** *********.:**:* :*** *: *** ****.:. * ****......* :****:.**:****.* *: :*: .:: * :.:...****** **.* :.** :.*:* . * . :. ::..:**: ...*: * .:** ::* .: * .* *. ... . .. *.:* .* . :.*:* : *.: :*:.**** ****: *.: *: .: *****:***********.**:**:**:*************:*****:***************:******************* **********:**:**:** ****:* ***************.***.**:***::*******.*.:*: : * ... *: *****::... :. :. :**. :..* *.* : : : .: . .* *. . :.:.: * * : .. :: *** *.:**********::** : :. ..:.. * . .* * .******:*.*******************.::*** *:*:**************:.**:*******:::.:::***:*.::*:***..*:.*: ***.:. .. .. . : : :::: . . * . ::.: * . : .:. .* * * :. *:** **.: . *:***... : * *... . *: * .*::. :.: . :.** :** ******:***:.** *****************************..***:******:*::*.****** ************:**:**:**:", "identical_positions": 1198, "similar_positions": 584, "identity": "50.87%" }, { "cls_id": "homologset.agr.MGI:1298377", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q60677-1", "uniprot_id": "ITAE_MOUSE", "id": "Q60677-1", "name": "Integrin alpha-E", "aln": "MKWLFHTLLCMASLKPQGAFNLDVDWAWVTALQPGAPAVLSSLLHQDPSNNQTCLLVARRSSNRNTAALYRCAISISPDEIACQPVEHICMPKGRYQGVTLVGNHNGVLVCIQVQARKFRSLNSELTGACSLLTPNLDLQAQAYFSDLEGFLDPGAHVDSGDYCRSKGGSTGEEKKSAR--RRRTVEEED---------EEEDGTEIAIVLDGSGSIEPSDFQKAKNFISTMMRNFYEKCFECNFALVQYGAVIQTEFDLQESRDINASLAKVQSIVQVKEVTKTASAMQHVLDNIFIPSRGSRKKALKVMVVLTDGDIFGDPLNLTTVINSPKMQGVVRFAIGVGDAFKNNNTYRELKLIASDPKEAHTFKVTNYSALDGLLSKLQQHIVHMEGTVGDALQYQLAQTGFSAQILDKGQVLLGTVGAFNWSGGALLYSTQNGRGCFLNQTAKE--DSRTVQYSYLGYSLAVLHKAHGVSYVAGAPRHKLRGAVFELRKEDREEDAFVRRIEGEQMGSYFGSVLCPVDIDMDGTTDFLLVAAPFYHIRGEEGRVYVYQVPEQDASFSLAHTLSGHPGLTNSRFGFAMAAVGDINQDKFTDVAIGAPLEGFGAGDGASYGSVYIYNGHSGGLYDSPSQQIRASSVASGLHYFGMSVSGGLDFNGDGLADITVGSRDSAVVLRSRPVVDLTVSMTFTPDALPMVFIGKMDVKLCFEVDSSGVASEPGLREMFLNFTVDVDVTKQRQRLQCEDSSGCQSCLRKWNGGSFLCEHFWLIS-TEELCEEDCFSNITIKVTYEFQTSGGRRDYPNPTLDHYKEPSAIFQLPYEKDCKNKVFCIAEIQLTTNISQQELVVGVTKEVTMNISLTNSGEDSYMTNMALNYPRNLQFKKIQKPVSPDVQCDDPKPVASVLVMNCKIGHPILKRSSVNVSVTWQLEESVFPNRTADITVTISNSNEK-SLARETRSLQFRHAFIAVLSRPSVMYMNTSQSPSDHKEFFFNVHGENLFGAVFQLQICVPIKLQDFQIVRVKNLTKTQDHTECTQSQEPACGSDPVQHVKEWHSVVCAITSNKENVTVAAEISVGHTKQLLRDVSELPILGEISFNKSLYEGLNAENHRTKITVIFLKEEETRSLPLIIGSSIGGLLVLVVIIAILFKCGFFKRKYQQLNLESTRRAQLKADSLLQD--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "M0R6T8-1", "uniprot_id": "M0R6T8_RAT", "id": "M0R6T8-1", "name": "", "aln": "MKWFFHALLCVASLKPLGAFNVDVDWSWVTALQPGAPSVLNSLLHQDPSNNQTCLLVARRSSNRNSAVLYRCATSIIPDEIGCQPVEHILMPKGRYQGVTLVRNHNGVLVCIQVQSRKPRSLNSELTGACSLLTPNLDLQAQAYFSDLEGVLDLGASVNSGDYYGSKGGSTGEETKSARRLRRQAVEEED---------EEEAGTEIAIVLDGSGSIEPSDFQKAKDFISTMMRNFYEKCFECNFALVQYGGVIQTEFDLLDSRDINASLAKVQSIVQVKEVTKTASAMQHVLDNIFIPSRGSRKKALKVMVVLTDGDIFRDPLNLTTVISSSKMQGVVRFAIGVGNAFENNNTYRELKLIASDPKAAHTFKVTNYSALDGLLSKLQQRIIHMEGTVGDTLQYQLAQTGFSAQILDKGQVLLGTVGAFNWSGGALLYNTQNGRGRFLNQTAKE--DFRAAQYSYLGYSVAALHKAHGVSYVAGAPRHKLRGAVFELQKEDGEE-TFMRRIEGEQMGSYFGSVLCPVDINMDGITDFLLVAAPFYHIRGEEGRVYVYRVHEQDAPFSLVYTLSGYPGLTSSRFGFAMAAVGDINQDKFTDVAIGAPLEGFGAGDGASYGSVYIYNGHSGGLHASPSQQIRASSVALGLYYFGMSVSGGLDFSGDDLADITVGSQDVAVVLRSRPVVDLTVSMTFTPDALPMAFKDKMDVELCFKVDSSAVPSEPGLRGMSLNFTVDVDVTKQKQRLQCADRSCCQSCLMKWSGGSSLCEHFGLISTEEELCEDDCFSNITIKVSYEFQTSEERRNHPNPILDHYKEPSAIFQLPYEKDCKNKVFCIAEIQLTTAISQQDLVVGITKEVTMNISLTNSGEDSYMTNMALNYPRNLQFKKIQKPLSPDIQCDDPKPVASVLVMNCKIGHPILKRSSVNVSVTWQLEESIFPNRTADITVTISNSNEK-SLARETHSLQFRHAFIAVLSRPSVMYMNTSQSSSDHKEFFFNVHGENHFGAVFQLQICVPITLRDLQIIRVKHLTKTQAHTECTQSQEPTCGSDPVQNVEEWHSVICAITSNKENVTVAAEISMGHTKQLLRDISELQILGEISFNKSLYEGLNAENHRTKITVIFLKEEKPHSLPLIIGSSIGGLLVLVVIIAILFKCGFFKRKYKQLNLESVRKAQLKSDSLLED--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P38570-1", "uniprot_id": "ITAE_HUMAN", "id": "P38570-1", "name": "Integrin alpha-E", "aln": "-MWLFHTLLCIASLALLAAFNVDVARPWLTPKG-GAPFVLSSLLHQDPSTNQTWLLVTSPRTKRTPGPLHRCS--LVQDEILCHPVEHVPIPKGRHRGVTVVRSHHGVLICIQVLVRRPHSLSSELTGTCSLLGPDLRPQAQANFFDLENLLDPDARVDTGDCYSNKEGGGEDDVNTARQRRALEKEEEEDKEEEEDEEEEEAGTEIAIILDGSGSIDPPDFQRAKDFISNMMRNFYEKCFECNFALVQYGGVIQTEFDLRDSQDVMASLARVQNITQVGSVTKTASAMQHVLDSIFTSSHGSRRKASKVMVVLTDGGIFEDPLNLTTVINSPKMQGVERFAIGVGEEFKSARTARELNLIASDPDETHAFKVTNYMALDGLLSKLRYNIISMEGTVGDALHYQLAQIGFSAQILDERQVLLGAVGAFDWSGGALLYDTRSRRGRFLNQTAAAAADAEAAQYSYLGYAVAVLHKTCSLSYIAGAPRYKHHGAVFELQKE-GREASFLPVLEGEQMGSYFGSELCPVDIDMDGSTDFLLVAAPFYHVHGEEGRVYVYRLSEQDGSFSLARILSGHPGFTNARFGFAMAAMGDLSQDKLTDVAIGAPLEGFGADDGASFGSVYIYNGHWDGLSASPSQRIRASTVAPGLQYFGMSMAGGFDISGDGLADITVGTLGQAVVFRSRPVVRLKVSMAFTPSALPIGFNGVVNVRLCFEISSVTTASESGLREALLNFTLDVDVGKQRRRLQCSDVRSCLGCLREWSSGSQLCEDLLLMPTEGELCEEDCFSNASVKVSYQLQTPEGQTDHPQPILDRYTEPFAIFQLPYEKACKNKLFCVAELQLATTVSQQELVVGLTKELTLNINLTNSGEDSYMTSMALNYPRNLQLKRMQKPPSPNIQCDDPQPVASVLIMNCRIGHPVLKRSSAHVSVVWQLEENAFPNRTADITVTVTNSNERRSLANETHTLQFRHGFVAVLSKPSIMYVNTGQGLSHHKEFLFHVHGENLFGAEYQLQICVPTKLRGLQVVAVKKLTRTQASTVCTWSQERACAYSSVQHVEEWHSVSCVIASDKENVTVAAEISWDHSEELLKDVTELQILGEISFNKSLYEGLNAENHRTKITVVFLKDEKYHSLPIIIKGSVGGLLVLIVILVILFKCGFFKRKYQQLNLESIRKAQLKSENLLEEEN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RMI4-1", "uniprot_id": "A0A8M1RMI4_DANRE", "id": "A0A8M1RMI4-1", "name": "", "aln": "---MYRKLLFMMVLCNATGFNVQISPLKHFTNE-------DPLFGQTIIQSKDGIFVPSPIYGG----LFECTLDNECSKVNISDENPKGMR-QVASVASLTSQDQHVVMCNQVRTKIRG--TEYLNGNCTLMSPSGKVKLSPAELDNNMDNNNNNNNNN-KYRGGRIDQVKWRKRREAQPNLGALEEEE-------EEEEDPGTEIAFVLDGSGSIQYDDFEKAKDFIHTTMSNVWKTCFDCNFAIVQYGSSIRTELSLLDNEDGARSLQKVKQIKQIYNLTKTASAINHVLTDIFIPENGSKNNSEKIIIVLSDGKILGDPMTLDEVLNKTQMKGVTRYSIGVGDGILKNKDAIKEMTQIADP--GKYYSVSSYGALNDILSSLERGIIGTEGTQHGFKLQLAEAGFSSHLLYNEQKVEALFGAVGAYDWSGGVFLKSGNTVKFLNDSHNE------TKFGYLGYSVTSAHLPSKTLYISGAPRYNLTGAVFIFDGLEKYV------LHGDQVGSYFGSVLCALDINKDEHTDHLLVGAPHFHLNGEEGKVLVYKLNQEDRFERAPVELRGDAGQTFARFGAAIGSIGDIDNNKFNDVAVGAPLE------TGSAGSVYIYSGFEEGLRFS--QKISPSDFGMKLVYFGQSVSVGPAPASD-IPCIAVGSLGRVSVFETIPVLIIEPTIKIDTEVIALTHQMNKISSELSMKITVCFNIKKGKLKAEKSETQAVDYEIDLDSGASKKRLTCGADSLIKDTFTLTPDEECTNKKLTYLGCFDCFSPIKIKLSFSLASN--KNEAPIRILDAFTPTEVVKEIPFEKDCQAADCKPSITLSDSKISETTITMGETQNLNINFNFTNTGDPSYKTTLTLTYPSILSERKIEGAACPVKNDNQIQCHLQHPVFTRSAQTNLFISWQLNDKSDLKKSEIIANLTSQNNGIQLLDSRIYTFNVMYFLPILIRGSAEPNILR----IEEGGKGKTQPIKFKIQFQGENKYGATIDVIITIKMDTSKTDLHITKIQPEVCVLEANKVKE-----------------ASYIYKCTLKELQIITIEANVFIHDVQDTSEKIIVEGQYSYDETLYSAKDTIKSFTLEVPVTKMQVMTSKGPIIGG-SIGGFLFLLIFIIILIKCGFFRRRHKVDQTQNQD--------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32T5M2-1", "uniprot_id": "A0AB32T5M2_DANRE", "id": "A0AB32T5M2-1", "name": "", "aln": "---MYRKLLFVMVLCNAAGFNIQISPVKHFTNE-------DPLFGQTIIQAKDGIFVPSPTYGR----LFKCTLDNECTKVNINDENPKGMR-PVASVASLTSQEQHVVMCNQVRTENRG--TEYLNGICTLVSPSGKVKLYPAELDNNKNNNNNNNNNNNKYQGGRINQ-------------------------------GPGTEIAFVLDGSGSIQDDDFQKAKDFIYNVMSNVWKTCFDCNFAIVQYGSLIRTELSLLDNEDRVGSLLKVKQIKQIYNLTKTASAINHVLTDIFIPENGSKDNSAKIIIVLSDGKILGDPMTLDEVLNKPQMKGVTRYSIGVGDGILKNLDATEEMMQIADP--GKYYNVSSYRALNDIVSSLERGIIGTK--------------------------------------------DPGTEIAFVLDGS---------------------------------------------------------------------------------------------------------------------------------------GSIQDDDFQKAKD---------------------FIYN-------------------------------------------------------------------------------------VMSNVWKTCFDCNFAIVQYG---------------------------SLIRTELLLLDNEDRAGSLLKVK---------QIKQIYNLTKT--ASAINHVLTDIFIP---------EKGSKNNTAKIIIVLSDGEILEDPMTLDEVLNK----------------------------PQMKGVTR--------------------------------------------------YSIGVGDG------------ILKKPNAVKEMMQ----IADPGK-----------YYSVSSYGALNDILSSLEREIIGTEAFTT----------------------------------------------------------ARTTAARIFDVAACHCHKSLLTHQGCLNHWCLLT------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::: ** : * .**::: . ..*: * : ::*. *..*: :: : : .::. ..: *::* ** . .. *.* *:*: *. : . * : : . :. . .: . *****::*******: **::**:** . * *.::.**:****:****. *:**:.* :..* ** :*:.* *: .:******::*** .** ...**: :: *:::**:** *: **:.* *:...:*:** *::****: : . : :** : :.*:.* **:.::*.*. *: : . *: : .:: * . :* .* :**. . : . :. :* :.: . * : ** .: : : :.:. . : ::: : : :. : : : : : .: . . :** :: : : . .: . .::* . : . ", "identical_positions": 113, "similar_positions": 181, "identity": "9.54%" }, { "cls_id": "homologset.agr.MGI:1298378", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88455-1", "uniprot_id": "DHCR7_MOUSE", "id": "O88455-1", "name": "7-dehydrocholesterol reductase", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASKSQHNAPKVKSP----NGKAGSQ--GQWGR-------AWEVDWFSLASIIFLLLFAPFIVYYFIMACDQYSCSLTAPALDIATGHASLADIWAKTP--PVTAKAAQLYALWVSFQVLLYSWLPDFCHRFLPGYVGGVQEGAITPAG-VVNKYEVNGLQAWLITHILWFVN--AYLLSWFSPTIIFDNWIPLLWCANILGYAVSTFAMIKG------YLFPTSAEDCKFTGNFFYNYMMGIEFNPRIGKWFDFKLFFNGRPGIVAWTLINLSFAAKQQELYGHVTNSMILVNVLQAIYVLDFFWNETWYLKTIDICHDHFGWYLGWGDCVWLPYLYTLQGLYLVYHPVQLSTPNALGILLLGLVGYYIFRMTNHQKDLFRRTDGRCLIWGKKPKAIECSYTSADGLKHHS---------------KLLVSGFWGVARHFNYTGDLMGSLAYCLACGGG-HLLPYFYIIYMTILLTHRCLRDEHRCANKYGRDWERYTAAVPYRLLPGIF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Z2Z8-1", "uniprot_id": "DHCR7_RAT", "id": "Q9Z2Z8-1", "name": "7-dehydrocholesterol reductase", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASKSQHNASKAKNH----NVKAESQ--GQWGR-------AWEVDWFSLVSVIFLLLFAPFIVYYFIMACDQYSCSLTAPILDVATGRASLADIWAKTP--PVTAKAAQLYALWVSFQVLLYSWLPDFCHRFLPGYVGGVQEGAITPAG-IVNKYEVNGLQAWLITHFLWFVN--AYLLSWFSPTIIFDNWIPLLWCANILGYAVSTFAMIKG------YLFPTSAEDCKFTGNFFYNYMMGIEFNPRIGKWFDFKLFFNGRPGIVAWTLINLSFAAKQQELYGHVTNSMILVNVLQAIYVLDFFWNETWYLKTIDICHDHFGWYLGWGDCVWLPYLYTLQGLYLVYHPVQLSTPNALGVLLLGLVGYYIFRMTNHQKDLFRRTDGHCLIWGKKPKAIECSYTSADGLKHRS---------------KLLVSGFWGVARHFNYTGDLMGSLAYCLACGGG-HLLPYFYIIYMTILLTHRCLRDEHRCANKYGRDWERYVAAVPYRLLPGIF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UBM7-1", "uniprot_id": "DHCR7_HUMAN", "id": "Q9UBM7-1", "name": "7-dehydrocholesterol reductase", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAAKSQPNIPKAKSLDGVTNDRTASQ--GQWGR-------AWEVDWFSLASVIFLLLFAPFIVYYFIMACDQYSCALTGPVVDIVTGHARLSDIWAKTP--PITRKAAQLYTLWVTFQVLLYTSLPDFCHKFLPGYVGGIQEGAVTPAG-VVNKYQINGLQAWLLTHLLWFAN--AHLLSWFSPTIIFDNWIPLLWCANILGYAVSTFAMVKG------YFFPTSARDCKFTGNFFYNYMMGIEFNPRIGKWFDFKLFFNGRPGIVAWTLINLSFAAKQRELHSHVTNAMVLVNVLQAIYVIDFFWNETWYLKTIDICHDHFGWYLGWGDCVWLPYLYTLQGLYLVYHPVQLSTPHAVGVLLLGLVGYYIFRVANHQKDLFRRTDGRCLIWGRKPKVIECSYTSADGQRHHS---------------KLLVSGFWGVARHFNYVGDLMGSLAYCLACGGG-HLLPYFYIIYMAILLTHRCLRDEHRCASKYGRDWERYTAAVPYRLLPGIF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7SXF1-1", "uniprot_id": "DHCR7_DANRE", "id": "Q7SXF1-1", "name": "7-dehydrocholesterol reductase", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMASDRVRKRHKGSANGAQTVEKEPSKEPAQWGR-------AWEVDWFSLSGVILLLCFAPFLVSFFIMACDQYQCSISHPLLDLYNGDATLFTIWNRAP--SFTWAAAKIYAIWVTFQVVLYMCVPDFLHKILPGYVGGVQDGARTPAG-LINKYEVNGLQCWLITHVLWVLN--AQHFHWFSPTIIIDNWIPLLWCTNILGYAVSTFAFIKA------YLFPTNPEDCKFTGNMFYNYMMGIEFNPRIGKWFDFKLFFNGRPGIVAWTLINLSYAAKQQELYGYVTNSMILVNVLQAVYVVDFFWNEAWYLKTIDICHDHFGWYLGWGDCVWLPFLYTLQGLYLVYNPIQLSTPHAAGVLILGLVGYYIFRVTNHQKDLFRRTEGNCSIWGKKPTFIECSYQSADGAIHKS---------------KLMTSGFWGVARHMNYTGDLMGSLAYCLACGGN-HLLPYFYIIYMTILLVHRCIRDEHRCSNKYGKDWERYTAAVSYRLLPNIF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8MLV1-1", "uniprot_id": "LBR_DROME", "id": "Q8MLV1-1", "name": "Lamin-B receptor", "aln": "MQHSPSTTTDHIHFAARFFDRNSYTMDRRLRRPRRTEDVSSGPLLAQSKQPSLLPVTRRTGSVTAAGATATATATAGPATRTRASPSRNKVVAPPSPDLGPRTRRSSRPRSSVGPLTGSGSGSSLPIKAAIKARTPIPEVSEVSSPIRLSTSNLPMTLTTNTSSGAPNKAFNTSSVNSGNSFSRTTTSSTTTTTERIEIRAEGDGEVDTDSIRKRITERLRRSVSKTISNLAGTPVTNTEEGSRYSRSVSRSVYDDEKSSKRSYSTGEEDIDEEDELEEDQFRSFNVTRKSATPAEISCRQLKAPREFGGWLGAFLFLLLLPTAVYYLTWSCTARNACQFKHLNLGILLDVNYLTRQVFQPRVVGAFAAYQVVVFLLVALLPGRRVHLTRETYKFNCLAVSLTLLIASGVAEYLKYPVVTFVLRHYLRFCIFGLVGAFVAAAWSYWLVDTAKYNVLRQTLTNDYGRTGSFVVDFALGRQLNPKWLGRVDWKQFQYRLS--LVTTLIYATCYIYQTLVWPQKP---QLGEQEGYLYQAKYYWNNVNYDPATLFSASCLLFYVLDAIIFEHHLSSSFELQHEGYGCLLLLRYAATPYLLTAVTKYFYEQRVPISCWYAPLAVAALLSLGLLVKRFSCAYKYKYRLNSQSPIFANIETIHTYQGSRLLLSGMWGWVRQPNYLGDIVALLALAAPMALRPAWPPVLGLSLIILLLLHRATRANARNQARYHSSWQRYSTQVRSYILPRVY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: . . . . *: . *. * * * .: .. : : * :: : . : * * :. . :: : : * . : . * . * *. : . : ::. :: * . . * : : *::: ::: : : .:..:::: : * ..* **.:. :: :* ::**: .*:* * . :. *** : * : . * : :* .::**:. * : :. . : :*: . . ::: : * : * * *: .:. *: : . . : . * . :.*:* :* :*: **:** .*: ** **::. ** . . . * : : : :** **. * : * :* .*:** : * :** ::", "identical_positions": 70, "similar_positions": 140, "identity": "9.38%" }, { "cls_id": "homologset.agr.MGI:1298379", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P43244-1", "uniprot_id": "MATR3_RAT", "id": "P43244-1", "name": "Matrin-3", "aln": "MSKSFQQSSLGRDSQGHGRDLSAAGIGLLAAATQSLSMPASLGRMNQGTARLASLMNLGMSSSLNQQGAHSALSSASTSSHNLQSIFNIGSRGPLPLSSQHRGDTDQASNILASFGLSARDLDELSRYPEDKITPENLPQILLQLKRRRTEEGPTLSYGRDGRSATREPPYRVPRDDWEEKRHFRRDSFDDRGPSLNPVLDYDHGSRSQESGYYDRMDYEDDRLRDGERCRDDSFFGETSHNYHKFDSEYERMGRGPGPLQERSLFEKKRGAPPSSNIEDFHGLLPKGYPHLCSICDLPVHSNKEWSQHINGASHSRRCQLLLEIYPEWNPDNDTGHTMGDPFMLQQSTNPAPGILGPPPPSFHLGGPAVGPRGNLGAGNGNLQGPRHMQKGRVETSRVVHIMDFQRGKNLRYQLLQLVEPFGVISNHLILNKINEAFIEMATTEDAQAAVDYYTTTPALVFGKPVRVHLSQKYKRIKKPEGKPDEKFDQKQELGRVIHLSNLPHSGYSDSAVLKLAEPYGKIKNYILMRMKSQAFIEMETREDAMAMVDHCLKKALWFQGRCVKVDLSEKYKKLVLRIPNRGIDLLKKDKSRKRSYSPDGKESPSDKKSKTDGAQKTENPAEGKEQEEKSGEDGEKDTKDDQTEQEPSMLLESEDELLVDEEEAAALIESGSSVGDETDLANLGDVSSDGKKEPSDKAVKKD--ASATSKKKLKKVDKIEELDQENEAALENGIKNEENTEPGAESAENADDPNKDASDNSDGQNDENKEDYTIPDEYRIGPYQPNVPGGIDYVIPKTGFYCKLCSLFYTNEEVAKNTHCSSLPHYQKLKKFLNKLAEERRQKKES", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K310-1", "uniprot_id": "MATR3_MOUSE", "id": "Q8K310-1", "name": "Matrin-3", "aln": "MSKSFQQSSLGRDSQGHGRDLSAAGIGLLAAATQSLSMPASLGRMNQGTARLASLMNLGMSSSLNQQGAHSALSSASTSSHNLQSIFNIGSRGPLPLSSQHRGDTDQASNILASFGLSARDLDELSRYPEDKITPENLPQILLQLKRRRTEEGPTLSYGRDGRSATREPPYRVPRDDWEEKRHFRRDSFDDRGPSLNPVLDYDHGSRSQESGYYDRMDYEDDRLRDGERCRDDSFFGETSHNYHKFDSEYERMGRGPGPLQERSLFEKKRGAPPSSNIEDFHGLLPKGYPHLCSICDLPVHSNKEWSQHINGASHSRRCQLLLEIYPEWNPDNDTGHTMGDPFMLQQSTNPAPGILGPPPPSFHLGGPAVGPRGNLGAGNGNLQGPRHMQKGRVETSRVVHIMDFQRGKNLRYQLLQLVEPFGVISNHLILNKINEAFIEMATTEDAQAAVDYYTTTPALVFGKPVRVHLSQKYKRIKKPEGKPDQKFDQKQELGRVIHLSNLPHSGYSDSAVLKLAEPYGKIKNYILMRMKSQAFIEMETREDAMAMVDHCLKKALWFQGRCVKVDLSEKYKKLVLRIPNRGIDLLKKDKSRKRSYSPDGKESPSDKKSKTD-AQKTESPAEGKEQEEKSGEDGEKDTKDDQTEQEPSMLLESEDELLVDEEEAAALLESGSSVGDETDLANLGDVSSDGKKEPSDKAVKKDPSASATSKKKLKKVDKIEELDQENEAALENGIKNEENTEPGAESAENADDPNKDTSENADGQNDENKEDYTIPDEYRIGPYQPNVPVGIDYVIPKTGFYCKLCSLFYTNEEVAKNTHCSSLPHYQKLKKFLNKLAEERRQKKET", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P43243-1", "uniprot_id": "MATR3_HUMAN", "id": "P43243-1", "name": "Matrin-3", "aln": "MSKSFQQSSLSRDSQGHGRDLSAAGIGLLAAATQSLSMPASLGRMNQGTARLASLMNLGMSSSLNQQGAHSALSSASTSSHNLQSIFNIGSRGPLPLSSQHRGDADQASNILASFGLSARDLDELSRYPEDKITPENLPQILLQLKRRRTEEGPTLSYGRDGRSATREPPYRVPRDDWEEKRHFRRDSFDDRGPSLNPVLDYDHGSRSQESGYYDRMDYEDDRLRDGERCRDDSFFGETSHNYHKFDSEYERMGRGPGPLQERSLFEKKRGAPPSSNIEDFHGLLPKGYPHLCSICDLPVHSNKEWSQHINGASHSRRCQLLLEIYPEWNPDNDTGHTMGDPFMLQQSTNPAPGILGPPPPSFHLGGPAVGPRGNLGAGNGNLQGPRHMQKGRVETSRVVHIMDFQRGKNLRYQLLQLVEPFGVISNHLILNKINEAFIEMATTEDAQAAVDYYTTTPALVFGKPVRVHLSQKYKRIKKPEGKPDQKFDQKQELGRVIHLSNLPHSGYSDSAVLKLAEPYGKIKNYILMRMKSQAFIEMETREDAMAMVDHCLKKALWFQGRCVKVDLSEKYKKLVLRIPNRGIDLLKKDKSRKRSYSPDGKESPSDKKSKTDGSQKTESSTEGKEQEEKSGEDGEKDTKDDQTEQEPNMLLESEDELLVDEEEAAALLESGSSVGDETDLANLGDVASDGKKEPSDKAVKKDGSASAAAKKKLKKVDKIEELDQENEAALENGIKNEENTEPGAESSENADDPNKDTSENADGQSDENKDDYTIPDEYRIGPYQPNVPVGIDYVIPKTGFYCKLCSLFYTNEEVAKNTHCSSLPHYQKLKKFLNKLAEERRQKKET", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**********.*********************************************************************************************:********************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************:******************************************************************************************************************************* :****..:**************************.*******************:******************:*************** ***::*************************************:*********:*:*:***.****:****************** ********************************************************:", "identical_positions": 824, "similar_positions": 19, "identity": "97.28%" }, { "cls_id": "homologset.agr.MGI:1298381", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35215-1", "uniprot_id": "DOPD_MOUSE", "id": "O35215-1", "name": "D-dopachrome decarboxylase", "aln": "MPFVELETNLPASRIPAGLENRLCAATATILDKPEDRVSVTIRPGMTLLMNKSTEPCAHLLVSSIGVVGTAEQNRTHSASFFKFLTEELSLDQD--------RIVIRFFPLEA-WQIG----------------KKGTVMTFL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LB54-1", "uniprot_id": "A0ABK0LB54_RAT", "id": "A0ABK0LB54-1", "name": "D-dopachrome decarboxylase", "aln": "MPFVELETNLPASRIPAGLENRLCAATATILDKPEDRVSVTIRPGMTLLMNKSTEPCAHLLISSIGVVGTAEQNRSHSSSFFKFLTEELSLDQDRYVELVRERICDSVLCMRLGWGVGDHLL--VPASTPCLSPRKCSVSAP-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P30046-1", "uniprot_id": "DOPD_HUMAN", "id": "P30046-1", "name": "D-dopachrome decarboxylase", "aln": "MPFLELDTNLPANRVPAGLEKRLCAAAASILGKPADRVNVTVRPGLAMALSGSTEPCAQLSISSIGVVGTAEDNRSHSAHFFEFLTKELALGQDR---------ILIRFFPLESWQIG----------------KIGTVMTFL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A6NHG4-1", "uniprot_id": "DDTL_HUMAN", "id": "A6NHG4-1", "name": "Putative D-dopachrome decarboxylase-like protein", "aln": "MPFLELDTNLPANRVPAGLEKRLCAAAASILGKPADRVNVTVRPGLAMALSGSTEPCAQLSISSIGVVGTAEDNRSHSAHFFEFLTKELALGQDR---------FPTVLSTSPAAHGGPRCPGEIIEGKKSCLNEEALFIYFI", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***:**:*****.*:*****:*****:*:**.** ***.**:***::: :. ******:* :**********:**:**: **:***:**:*.** : * . . ", "identical_positions": 66, "similar_positions": 27, "identity": "46.15%" }, { "cls_id": "homologset.agr.MGI:1298382", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9R1Q7-1", "uniprot_id": "PLP2_MOUSE", "id": "Q9R1Q7-1", "name": "Proteolipid protein 2", "aln": "MADSERLSAPGCWLACTSFSRTKKGILLFAEIILCLVILICFSASTTSAYSSLSVIEMICAAVLLVFYTCDLHSKISFINWPWTDFFRSLIATILYLITSIVVLVEGRGS-SRVVAGILGLLATLLFGYDAYITFP-LKQQR-HTAAPTDPTDGP-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZT52-1", "uniprot_id": "A0A8I5ZT52_RAT", "id": "A0A8I5ZT52-1", "name": "Proteolipid protein 2", "aln": "MADSERLSAPGCWLACTSFSRSKKGILLFAEIILCLVILICFSAS-TSAYSSLLAIEMIFVAVLFVFYVCHLHSKISFISWPWTDFFRSLIA-ILYLITSIVVLVEGRGS-SIFVAGVLGLLATLLFGYDAYITFP-LKQQR-HTASPTDPTNGP-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6P742-1", "uniprot_id": "PLP2_RAT", "id": "Q6P742-1", "name": "Proteolipid protein 2", "aln": "MADSERLSAPGCWLACTSFSRTKKGILLFAEIILCLVILICFSAS-TSAYSSLSVIEMIFAAVLFVFYMCDLHSKISFINWPWTDFFRSLIAAILYLITSIVVLVEGRGS-SKIVAGVLGLLATLLFGYDAYITFP-LKQQR-HTAAPTDPTDGP-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q04941-1", "uniprot_id": "PLP2_HUMAN", "id": "Q04941-1", "name": "Proteolipid protein 2", "aln": "MADSERLSAPGCWAACTNFSRTRKGILLFAEIILCLVILICFSAS-TPGYSSLSVIEMILAAIFFVVYMCDLHTKIPFINWPWSDFFRTLIAAILYLITSIVVLVERGNH-SKIVAGVLGLIATCLFGYDAYVTFP-VRQPR-HTAAPTDPADGPV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0S6H4-1", "uniprot_id": "B0S6H4_DANRE", "id": "B0S6H4-1", "name": "Proteolipid protein 2", "aln": "MAETEGSPFGGCLEKLMSYARTRKGTILAAEILLSFIILICYAASMYGGYTAVAICEMVFAIIFFVVYMLELDKQFLVVNWLWSDLFRAVIGAALYIITSLICVIGGTGDGARIAGGVFGLLAGILFAYDSYTLYLDIKSSRQHAAAPTDDRV---", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**::* . ** .::*::** :* ***:*.::****::** .*::: **: . :::*.* .*..:: .:.* *:*:**::*. **:***:: :: . : ...*::**:* **.**:* : ::. * *:*:*** ", "identical_positions": 51, "similar_positions": 59, "identity": "32.69%" }, { "cls_id": "homologset.agr.MGI:1298386", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6G8U7-1", "uniprot_id": "A0A8I6G8U7_RAT", "id": "A0A8I6G8U7-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------MEAQAQGLLETEPLQG--RDGDAIGSADLSSMLS-------EEEKDELKAELVQLEEEITTLRQVLSAKERHLVEIKQKLGMNLMNELKQNFSRSWHDMQTTTAYKKTHETLSHAGQKATAAFSNVGTAISRKFGDMRSHSIGYSIRHSIS--MPAMRNSPTFKSFEERVETTVTSLKTKVGGTNHSGGSFEEVLSSTAHASSQNASAGIRQTREEDLQC-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O54818-1", "uniprot_id": "TPD53_MOUSE", "id": "O54818-1", "name": "Tumor protein D53", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------MEAQAQGLLETEPLQG--RDGDAVGSADFSSMLS-------EEEKEELKAELIQLEDEITTLRQVLSAKERHLVEIKQKLGMNLMNELKQNFSRSWHDMQTTTAYKKTHETLSHAGQKATAAFNNVGTAISKKFGDMR-----YSIRHSIS--MPAMRNSSTFKSFEERVETTVASLKTKVGGTNHGGGSFEEVLNSTAHASSQNASAGSRQTKDEELQC-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q16890-1", "uniprot_id": "TPD53_HUMAN", "id": "Q16890-1", "name": "Tumor protein D53", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------MEAQAQGLLETEPLQG--TDEDAVASADFSSMLS-------EEEKEELKAELVQLEDEITTLRQVLSAKERHLVEIKQKLGMNLMNELKQNFSKSWHDMQTTTAYKKTHETLSHAGQKATAAFSNVGTAISKKFGDMS-----YSIRHSIS--MPAMRNSPTFKSFEERVETTVTSLKTKVGGTNPNGGSFEEVLSSTAHASAQSLAGGSRRTKEEELQC-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B7R8-1", "uniprot_id": "A0A8M2B7R8_DANRE", "id": "A0A8M2B7R8-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------MEPRQQGLLDKESLKE--ADEDMVSEVDLNNTYT-------EEEREEMENELTKLEEEITTLKQVLASKEKRHLELKQKLGITALSELRHNFNKSWNDMQTSTVYKKTSETLSTAGQRTSAAFSNLGTAISRKFGDMRSYSIGYSVRHSMS--MPAMRNSPSFKSFEEKVESTVSNIKSKVGGTG-GAGSFEEVLSSAAHASAQDTPTNN-VTESSERSC-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4K897-1", "uniprot_id": "A0A0B4K897_DROME", "id": "A0A0B4K897-1", "name": "Tumor protein D52", "aln": "MSESEPNSLEFIEDPYLPSIDDLTSTPSLDLETNDAVLDWYGDGQEESEAELYLRNLTLDQIFYDVDSDYTNSLELQAVEADFIAAKLANQAPSSSMAKRFRLKFFAKRTMRDVKVTFIDFSKPYLAKISNSDNYKRFLNIGHRSRGTKFDNTANLSEPASPANSVASAEIAAEFAALSVEEKEQRRAEWSQELARVEEEINTLRTVLASKTRHASDLKRKLGITVWKEVTDDVNQGLKNLKESTVYQSVEQSVGTFTKTVYEAPLYQRTESVLKSTGEKTASVFGSITSGISSKLSQMKNSESMRSIEASVGSAYENVKVSYEHNNFMCQSHATKVTSRSGSVSSFPDALDENNTSSGLNSPTDSLPK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ..: : :. *. : :...:: : *:.: * . ** ::*:**.**: **::* :: ::*:***:. .*: .:..:. :::: :*.*:.. :::. : . * * * . *: .:* :. *:** :::*:* * :: .:* . .. *. :.* : : :. . .. .. ", "identical_positions": 34, "similar_positions": 86, "identity": "9.21%" }, { "cls_id": "homologset.agr.MGI:1298387", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WUH4-1", "uniprot_id": "FHL1_RAT", "id": "Q9WUH4-1", "name": "Four and a half LIM domains protein 1", "aln": "MSEKFDCHYCRDPLQGKKYVQKDGRHCCLKCFDKFCANTCVECRKPISADAKEVHYKNRYWHDTCFRCAKCLHPLASETFVSKDGKILCNKCATREDSPRCKGCFKAIVAGDQNVEYKGTIWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQPWHAECFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNL---ANKRFVFHNEQVYCPDCAKKL----------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97447-1", "uniprot_id": "FHL1_MOUSE", "id": "P97447-1", "name": "Four and a half LIM domains protein 1", "aln": "MSEKFDCHYCRDPLQGKKYVQKDGRHCCLKCFDKFCANTCVDCRKPISADAKEVHYKNRYWHDNCFRCAKCLHPLASETFVSKDGKILCNKCATREDSPRCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQPWHAECFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNL---ANKRFVFHNEQVYCPDCAKKL----------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13642-2", "uniprot_id": "FHL1_HUMAN", "id": "Q13642-2", "name": "Four and a half LIM domains protein 1", "aln": "MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGKRTVSRVSHPVSKARKPPVCHGKRLPLTLFPSANLRGRHPGGERTCPSWVVVLYRKNRSLAAPRGPGLVKAPVWWPMKDNPGTTTASTAKNAP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B625-1", "uniprot_id": "A0ACD6B625_DANRE", "id": "A0ACD6B625-1", "name": "Four and a half LIM domains protein 1", "aln": "MASRSNCFYCREDLSGKKFVRKDEKQVCVRCFDKFCANTCTECRCTISTDSKELHHKGKYWHSDCFRCAKCYKNLAKESFTSKDDRILCGTCSSREDAPRCHGCYKPILPGTENVEYKGNSWHDECFKCYQCQKPIGNKSFITKNNNVYCSPCHEKKFAKQCACCKKPITTGGVNYQDQPWHSECFVCSSCRKPLAGTRFTSHEEKVYCVDCYKSTVAKKCSGCQNPITGFGKATNVVNYEGGSWHDYCFNCKKCSLNL---ADKRFVAHSGHIYCSDCSKKL----------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:.: :*.***: *.***:*:** :: *::**********.:** .*.:*:**:*:*.::**. ******* : **.*:*.:**.:***..*::***:*:*:**:*.*:.* :******. **.:**.* :*:: **. **:.*.::.** .***.****:*. *:*.**:**:.*******::**** :* * *** ***: *:: *******. *****:**:***** . : * . : : : *: .:.* *: * . . *.. * ", "identical_positions": 139, "similar_positions": 91, "identity": "43.03%" }, { "cls_id": "homologset.agr.MGI:1298388", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P13439-1", "uniprot_id": "UMPS_MOUSE", "id": "P13439-1", "name": "Uridine 5'-monophosphate synthase", "aln": "-MEVASQALGPLVTELYDVQAFKFGSFVLKSGLSSPVYIDLRGIVSRPRLLSQVADILFQTAKNAGISFDSVCGVPYTALPLATVICSANHIPMLIRRKETKDYGTKRLVEGEINPGQTCLVIEDVVTSGASVLETVEVLQKEGLKVTDAIVLLDREQGGKDKLQAQGIRLHAVCTLSQMLEILQQQEKIDADMVGRVKRFIQ------ENVFSAANHNGLPPPEKKACKELSFGARAELPGTHPLASKLLRLMQKKETNLCLSADVSEARELLQLADALGPSICMLKTHVDILNDFTLD-VMEELTALAKRHEFLIFEDRKFADIGNTVKKQYESGTFKIASWADIVNAHVVPGSGVVKGLQE-VGLPLH---RACLLIAEMSSAGSLATGNYTKAAVGMAEE--HCEFVIGFISGSRVSMKPE---FLHLTPGVQLETGGDHLGQQYNSPQEVIGKRGSDVIIVGRGILA-AANRLEAAEMYRKAAWEAYLSRLAVQ-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0M2N2-1", "uniprot_id": "A0ABK0M2N2_RAT", "id": "A0ABK0M2N2-1", "name": "Uridine 5'-monophosphate synthase", "aln": "-MEVARQALGPLVTELYDVQAFKFGSFVLKSGLSSPVYIDLRGIVSRPRLLSQVADILFQTARNAGISFDSVCGVPYTALPLATVICSANHIPMLIRRKETKDYGTKRLVEGEINPGQTCLVIEDVVTSGASVLETVEVLQKEGLKVTDAIVLLDREQGGKDKLQAQGIRLHSVCTLSEMLEILEQQKKIDAEMVGRVKRFIQ------ENVFTAANHNGVPPPEKKACKELSFGARAELPGVHPLASKLLTLMQKKETNLCLSADVSEARELLQLADALGPSICMLKTHVDILNDFTLD-VMEELTTLAKRHEFLIFEDRKFADIGNTVKKQYESGIFKIASWADVVNAHVVPGSGVVKGLQE-VGLPLH---RACLLIAEMSSAGSLATGDYTKAAVGMAEE--HCEFVIGFISGSRVSMKPE---FLHLTPGVQLETGGDHLGQQYNSPQEVVGKRGSDVIIVGRGILA-AANRLEAAEMYRKAAWEAYLSFTAVNRHHDQGKSYKNSM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P11172-1", "uniprot_id": "UMPS_HUMAN", "id": "P11172-1", "name": "Uridine 5'-monophosphate synthase", "aln": "-MAVARAALGPLVTGLYDVQAFKFGDFVLKSGLSSPIYIDLRGIVSRPRLLSQVADILFQTAQNAGISFDTVCGVPYTALPLATVICSTNQIPMLIRRKETKDYGTKRLVEGTINPGETCLIIEDVVTSGSSVLETVEVLQKEGLKVTDAIVLLDREQGGKDKLQAHGIRLHSVCTLSKMLEILEQQKKVDAETVGRVKRFIQ------ENVFVAANHNGSPLSIKEAPKELSFGARAELPRIHPVASKLLRLMQKKETNLCLSADVSLARELLQLADALGPSICMLKTHVDILNDFTLD-VMKELITLAKCHEFLIFEDRKFADIGNTVKKQYEGGIFKIASWADLVNAHVVPGSGVVKGLQE-VGLPLH---RGCLLIAEMSSTGSLATGDYTRAAVRMAEE--HSEFVVGFISGSRVSMKPE---FLHLTPGVQLEAGGDNLGQQYNSPQEVIGKRGSDIIIVGRGIIS-AADRLEAAEMYRKAAWEAYLSRLGV--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B8JLL1-1", "uniprot_id": "B8JLL1_DANRE", "id": "B8JLL1-1", "name": "Uridine 5'-monophosphate synthase", "aln": "---MDDTSLDSLILKLHDIQAVKFGTFKLKSGLSSPIYFDLRVIVSHPALMNQVADLLHKKSEEAGVQFDSVCGVPYTALPLATIICSSKQYPMLIRRKEAKDYGTKRLIEGTIRPGDRCLIVEDVVTSGSSVLETAEVLEKEGLKITDAVVLMDREQGGSTRLADSGITLHSVISISRLLEVLLKAGRIDTDTAQSVKRFVQ------DNNTYILKKNGSS-AAKKSCGELSYGARAGLPDTHPLAARLMQIMEDKKTNLCVSADVTHSKELLDIAVTLGPLICVLKTHVDILEDFTAD-VASNLKELAKKHNFLIFEDRKFADIGNTVKHQYEGGLYRISSWAHIINAHALPGPGVLQGLGG-VGNPLG---HGCLLIAQMSSQGSLATGDYTQAVVKMAED--HSDFVFGFISGSKISEKPG---MVHMTPGVQMQTGGDGLGQQYSSPEDVICTKGSDIIIVGRGILG-SPDRLRAAGEYRTAGWEAYLKRLSLAS------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P03962-1", "uniprot_id": "PYRF_YEAST", "id": "P03962-1", "name": "Orotidine 5'-phosphate decarboxylase", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSKATYKERAAT-HPSPVAAKLFNIMHEKQTNLCASLDVRTTKELLELVEALGPKICLLKTHVDILTDFSMEGTVKPLKALSAKYNFLLFEDRKFADIGNTVKLQYSAGVYRIAEWADITNAHGVVGPGIVSGLKQ-AAEEVTKEPRGLLMLAELSCKGSLATGEYTKGTVDIAKS--DKDFVIGFIAQRDMGGRDEGYDWLIMTPGVGLDDKGDALGQQYRTVDDVVST-GSDIIIVGRGLFAKGRDAKVEGERYRKAGWEAYLRRCGQQN------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q01637-1", "uniprot_id": "UMPS_DROME", "id": "Q01637-1", "name": "Uridine 5'-monophosphate synthase", "aln": "MVAQNSDKMRALALKLFEINAFKFGDFKMKVGINSPVYFDLRVIVSYPDVMQTVSDLLVEHIKDKQLSAKHVCGVPYTALPLATIVSVQQGTPMLVRRKEAKAYGTKKLVEGIFNAGDTCLIVEDVVTSGSSILDTVRDLQGEGIVVTDAVVVVDREQGGVANIAKHGVRMHSLFTLSFLLNTLHEAGRIEKSTVEAVAKYIAAVQINSDGTFVGGDKGDVVRANDLQRTKLTYENRANL-AKSAVAKRLFNLIASKQTNLCLAADLTHADEILDVADKCGPYICLLKTHVDIVEDFSDK-FIADLQALAQRHNFLLMEDRKFADIGNTVSLQYGKGIYKISSWADLVTAHTLPGRSILQGLKAGLGEGGAGKERGVFLLAEMSASGNLIDAKYKENSNKIATEGADVDFVAGVVCQSSDAFAFPG--LLQLTPGVKIDEGVDQLGQQYQSPEHVVKERGADIGVVGRGILK-ASSPKQAAQTYRDRLWAAYQDRVAK--------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: ** .:* :*: :: .*:**** : *: : *:*::. ** **:*******: **: . * *: ::**::************. ** * ::*:.**.: .** : * .::.** . :. :::*::*. *.* ..*.. :* . . :** *.:. . : :**** :: * ***** : :.*: *:*: :****:: . . . ** * ** . ", "identical_positions": 83, "similar_positions": 79, "identity": "16.21%" }, { "cls_id": "homologset.agr.MGI:1298389", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z2H6-1", "uniprot_id": "CLC4D_MOUSE", "id": "Q9Z2H6-1", "name": "C-type lectin domain family 4 member D", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MWLEESQMKSKGTRHPQLIPCVFAVVSISFLSACFISTCLVTHHYFLRWTRGSVVKLSDYHTRVTCIREEPQ-------P-GATGGTWTCCPVSWRAFQSNCYFPLNDN-QTWHESERNCSGMSSHLVTINTEAEQN-----FVTQLLDKRFSYFLGLADENVEGQWQWVDKTP------------------FNPHTVFWEKGESNDFMEED-------------CVVLVHVH--EKWVWNDFPCHFEVRRICKLPGITFNWKPSK---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q69FH1-1", "uniprot_id": "CLC4D_RAT", "id": "Q69FH1-1", "name": "C-type lectin domain family 4 member D", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MWLEESQMKSKGALHPRRIPWVCAVVSISFLSACFISTCVVT-HYFLLWKRGSALKFSDYHTRLTCILEEPQ-------P-GATGGTWTCCPVSWRAFQSNCYFALNDN-QTWHESERNCSGMSSHLVTINTEAEQD-----FVTQLLDEQFSYFLGLSYEKVEGQWQWVDKTP------------------FNPNVVFWKVGEPKDSMEED-------------CVVLVYDQ--DKWVWNDFPCHFEMGRICKLPGATFDWNPSK---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8WXI8-1", "uniprot_id": "CLC4D_HUMAN", "id": "Q8WXI8-1", "name": "C-type lectin domain family 4 member D", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGLEKPQSKLEGGMHPQLIPSVIAVVFILLLSVCFIASCLVTHHNFSRCKRGTGVHKLEHHAKLKCIKEKSE-------LKSAEGSTWNCCPIDWRAFQSNCYFPLTDN-KTWAESERNCSGMGAHLMTISTEAEQN-----FIIQFLDRRLSYFLGLRDENAKGQWRWVDQTP------------------FNPRRVFWHKNEPDNSQGEN-------------CVVLVYNQ--DKWAWNDVPCNFEASRICKIPGTTLN--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q59DY5-1", "uniprot_id": "LEDL3_DROME", "id": "Q59DY5-1", "name": "C-type lectin 37Db", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMVKLLLLFLVCWSALPLES---------------------------------------SPLGNRYN------LEIGEKQYYISLAK-TNWFEASNHCRQNGGFLLNLESREELE-----LLSPHLHPAYSYWLSINDLGERGVY-VSEATG------------------LEAPFLNWSAGEPDNSSGYDR------------CVELWLST--TSFQMNDLPCYSSVAFICQLN-------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "B7Z0K3-1", "uniprot_id": "B7Z0K3_DROME", "id": "B7Z0K3-1", "name": "C-type lectin domain-containing protein", "aln": "MPPAGQQLRLTALVYLALGIALLCNGSDGETRQKYANESLADADDPSPVWSQFLEDYVLSQGSSSSGSQRKSKDLPYMGADMGINGPLSYHSSAYKRPGNNIYITRRIGEAVELEPHLRKPVESQSPIVNPQFRPMTNQMLHQQHQQMQQQQQQQQLQQRQQPGFLQQLFGIGGSGGGGGSGTQQQQHVRPVPLQQQQVQQIAQQHPQQQHLVGGQPTTFRAVSENDLYLLGAIEKLVYRVDYLESRVRRSEQLIYYLMAGNNQKEVKDPCPANFTRISDNCYYINSQQQVNWKTANSACKGLNSHLAEFEKVSENEEIMAYLLNQPTHRGRDYWLGGLNPGLLWIWSNSAKPVNPNMNLTSIAMAQKGENSTAANLVDSSEQAAEEATGEDVLNNTVQIEGKGRCLRLSYNAGKHSYVYYGQECTSRHYYICEHEDKTLDNKIKKITRELKLFE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . : . : .: *: : .* :. * ...* :.. * : :: . .*:*. : . . : ..: : *: * .: . * **: ", "identical_positions": 12, "similar_positions": 39, "identity": "2.64%" }, { "cls_id": "homologset.agr.MGI:1298390", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LRV2-1", "uniprot_id": "A0ABK0LRV2_RAT", "id": "A0ABK0LRV2-1", "name": "Switch-associated protein 70", "aln": "MGGLKDELLKAIWHAFTALDLDRSGKVSKSQLKVLSHNLCTVLKVPHDPVALEEHFRDDDEGPVSNQGYMPYLNKFILEKVQDNFDKIEFNRMCWTLCVKKNLTKSPLLITEDDAFKVWVIFNFLSEDKYPLIIVPEEIEYLLKKLTEAMGGGWQQEQFEHYKINFDDNKDGLSAWELIELIGNGQFSKGMDRQTVSMAINEVFNELILDVLKQGYMMKKGHKRKNWTERWFVLKPNIISYYVSEDLKDKKGDIMLDENCCVESLPDKDGKKCLFLIKCFDKTFEISASDKKKKQEWIQAIHSTIHLLKLGSPPPHKEARQRRKELRRKLLAEQEELERQMKELQAANENKQQELESVRKKLEEAASRAADEEKKRLQTQVELQTRFSTELEREKLIRQQMEEQVAQKSSELEQYLQRVRELEDMYLKLQEALEDERQARQDEETVRKLQARLLEEESSKRAELEKWHLAQQQAIQTTEAEKQELEQQRVLKEQALQEAMAQLEQLELERKQALEQYEGVKRKLEMATNTTKSWKDKVAHHEGLIRLIEPGSKNPHLITNWGPAAFTQAELEEREKSWKEKKTTD----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6A028-1", "uniprot_id": "SWP70_MOUSE", "id": "Q6A028-1", "name": "Switch-associated protein 70", "aln": "MRGLKDELLKAIWHAFTALDLDRSGKVSKSQLKVLSHNLCTVLKVPHDPVALEEHFRDDDEGPVSNQGYMPYLNKFILEKVQDNFDKIEFNRMCWTLCVKKNLTKSPLLITEDDAFKVWVIFNFLSEDKYPLIIVPEEIEYLLKKLTEAMGGGWQQEQFEHYKINFDDNKDGLSAWELIELIGNGQFSKGMDRQTVSMAINEVFNELILDVLKQGYMMKKGHKRKNWTERWFVLKPNIISYYVSEDLKDKKGDILLDENCCVESLPDKDGKKCLFLIKCFDKTFEISASDKKKKQEWIQAIYSTIHLLKLGSPPPHKEARQRRKELRRKLLAEQEELERQMKELQAANENKQQELESVRKKLEEAASRAADEEKKRLQTQVELQTRFSTELEREKLIRQQMEEQVAQKSSELEQYLQRVRELEDMYLKLQEALEDERQARQDEETVRKLQARLLEEESSKRAELEKWHLEQQQAIQTTEAEKQELEQQRVMKEQALQEAMAQLEQLELERKQALEQYEGVKKKLEMATHMTKSWKDKVAHHEGLIRLIEPGSKNPHLITNWGPAAFTQAELEEREKSWKEKKTTE----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UH65-1", "uniprot_id": "SWP70_HUMAN", "id": "Q9UH65-1", "name": "Switch-associated protein 70", "aln": "MGSLKEELLKAIWHAFTALDQDHSGKVSKSQLKVLSHNLCTVLKVPHDPVALEEHFRDDDEGPVSNQGYMPYLNRFILEKVQDNFDKIEFNRMCWTLCVKKNLTKNPLLITEEDAFKIWVIFNFLSEDKYPLIIVSEEIEYLLKKLTEAMGGGWQQEQFEHYKINFDDSKNGLSAWELIELIGNGQFSKGMDRQTVSMAINEVFNELILDVLKQGYMMKKGHRRKNWTERWFVLKPNIISYYVSEDLKDKKGDILLDENCCVESLPDKDGKKCLFLVKCFDKTFEISASDKKKKQEWIQAIHSTIHLLKLGSPPPHKEARQRRKELRKKQLAEQEELERQMKELQAANESKQQELEAVRKKLEEAASRAAEEEKKRLQTQVELQARFSTELEREKLIRQQMEEQVAQKSSELEQYLQRVRELEDMYLKLQEALEDERQARQDEETVRKLQARLLEEESSKRAELEKWHLEQQQAIQTTEAEKQELENQRVLKEQALQEAMEQLEQLELERKQALEQYEEVKKKLEMATNKTKSWKDKVAHHEGLIRLIEPGSKNPHLITNWGPAAFTEAELEEREKNWKEKKTTE----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LYE0-1", "uniprot_id": "Q1LYE0_DANRE", "id": "Q1LYE0-1", "name": "Switch-associated protein 70", "aln": "MG-LRDELLKAIWHAFTALDVDKSGKVSKSQLKVLSHNLCTVMKIPHDPVALEEHFRDDDEGPVSNQGYMPYLNRFILDKVQDNFDRIDFNRMCWTLCARKNLNRNHLLISDDDAFKIWCIFNFLSEDKYPLVMVSEEIEYFLRKLTEAMGGSWIEEKFEQYKLQLSSKHQCLKVWELIELVGMGHFSKGMDRQTLSMGITEVFHELILDVLKQGYMMKKGHKRKNWTERWFLLKPSLISYYVSEDLTEKKGDILLDGNCCVESLPDKEGKKCLFYVKCSDKSFEISASDKKKKQEWIQAIQTCITLLKVGRPAPHHEARQKRRELRQKQQAEQEELELRMRELQMANENKQRELEAMRKKLEEAAANAADEERRRLQTQNELQDLYRLEMEKEKMVRQQMEEQVAQKSNELEQYLQRVRELENMYHSLEEALEEERQARQDEETVRKLQARLLEEEVSKRAELEEIHLYQQQTISQTQAEKQELERERLAKESALESAMQQLHQLEADRQGALEQYQEVMKKLSDAANNTKSWKDKVAQHEGLIRLIQPGPKYPQKITNWGPAAFTDAELNLREKDWQEKKNRPATPQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB13A3H9-1", "uniprot_id": "A0AB13A3H9_DANRE", "id": "A0AB13A3H9-1", "name": "Switch-associated protein 70", "aln": "-MISKEEILKPIWYAFTALDLDRNGKVSKSQLKVLSHNLCTILKIPHNTSALEEHFKDDDEGPVSTQGYMPYLNTFILSKIQPNFDFVELNKMCWTLSAPKHINTMNLLMSEKDAFRVWCIFNFLSEDKYPLTIVTEELEYFLRKLLTAMGCSWNEGRFEDYKMHLNAKKHHLNAWELIELIDMGNFTKGINPQTVSMGINEVFQELVMDVIKQGYMMKKGHKRKNWTERWFELHLNYMSYYVSEDLVEQKGCIPLDRNCCVESMPDKDGKKNLFIIRCVEKSFEISASDKKAKQEWIQAIQDCIVRIRQGLSSAHRESRQKRRELRNRIKAEQEILENRMKQLQLANESKQAQLEALSKDLNKATARGDLEEQRRLQAQKELLEQYKRDLEQEKMARMQMEEQVIEKSNEVEQYWQRMQELEEMYLQLKQALQDEKQAKEDEEILRKLQARLLQEEENKRLELEQIHLQQQRVLSQSQKEKEELAKEREEKERALQAAQEQLESLKRQREGAEEEYMAVTKKLERASKKTKTWKHKVSKHEGLLKLVQPGGKTPSKMTNWGQAAFTESELNELEKMWQVNKNRSEEE-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::*:**.**:****** *:.*****************::*:**:. ******:********.******** ***.*:* *** :::*:*****.. *::. **:::.***::* ************ :*.**:**:*:** *** .* : :**.**:::. .:. *..******:. *:*:**:: **:**.*.***:**::**:**********:********* *: . :******** ::** * ** ******:***:*** ** ::* :*:********* ******** * :: * ...*:*:**:*:***.: **** ** :*::** ***.** :**:: *.*::*::.. **::***:* ** : ::*:**: * ****** :**.*:*** **::***:** .*::**::*:**::*** :********:** .** ***: ** **:.:. :: **:** .:* ** **: * **..*: :*: * *:* * :**. *:: **:**.**::****::*::** * * :**** ****::**: ** *: :*. ", "identical_positions": 330, "similar_positions": 160, "identity": "56.03%" }, { "cls_id": "homologset.agr.MGI:1298392", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5FVJ6-1", "uniprot_id": "BSCL2_RAT", "id": "Q5FVJ6-1", "name": "Seipin", "aln": "------------------------MVNDPPVPALLWAQEVGHVLAGRARRLMLQFGVLFCTILLLLWVSVFLYGSFYYSYMPTVSHLSPVHFYY-RTDCDSSTASLCSFPVANVSLTKSGRDRVLMYGQPYRVTLELELPESPVNQDLGMFLVTVSCYTRGGRIISTSSRSVMLHYRSQLLQMLDTLVFSSLLLFGFAEQKQLLEVELYSDYRENSYVPTTGAIIEVHSKRVQMYGAYLRIHAHFTGLRYLLYNFPMTCAFVGVASNFTFLSVIALFSYMQW-VWGAVWPRHRFSLQVNIRQRD---NSGHGAQRRISRHQPG----QASTQQSDVTEDGESPE-DPSGTEGQLSEEEKPEKQPLNGEGEQEPEAS----DGS--WEDAALLTEA------STSALAP--ETLGS-------LRQRQTCSSS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z2E9-1", "uniprot_id": "BSCL2_MOUSE", "id": "Q9Z2E9-1", "name": "Seipin", "aln": "------------------------MVNDPPVPALLWAQEVGHVLAGRARRLMLQFGVLFCTILLLLWVSVFLYGSFYYSYMPTVSHLSPVHFHY-RTDCDSSTASLCSFPVANVSLAKSGRDRVLMYGQPYRVTLELELPESPVNQDLGMFLVTVSCYTRGGRIISTSSRSVMLHYRSQLLQVLDTLLFSSLLLFGFAEQKQLLEVELYSDYRENSYVPTTGAIIEIHSKRIQMYGAYLRIHAHFTGLRYLLYNFPMTCAFVGVASNFTFLSVIVLFSYMQW-VWGAVWPRHRFSLQVNIRQRD---NSHHGAPRRISRHQPG----QESTQQSDVTEDGESPE-DPSGTEGQLSEEEKPEKRPLNGEEEQEPEAS----DGS--WEDAALLTEANPPTSASASALAP--ETLGS-------LRQRPTCSSS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96G97-2", "uniprot_id": "BSCL2_HUMAN", "id": "Q96G97-2", "name": "Seipin", "aln": "------------------------MVNDPPVPALLWAQEVGQVLAGRARRLLLQFGVLFCTILLLLWVSVFLYGSFYYSYMPTVSHLSPVHFYY-RTDCDSSTTSLCSFPVANVSLTKGGRDRVLMYGQPYRVTLELELPESPVNQDLGMFLVTISCYTRGGRIISTSSRSVMLHYRSDLLQMLDTLVFSSLLLFGFAEQKQLLEVELYADYRENSYVPTTGAIIEIHSKRIQLYGAYLRIHAHFTGLRYLLYNFPMTCAFIGVASNFTFLSVIVLFSYMQW-VWGGIWPRHRFSLQVNIRKRD---NSRKEVQRRISAHQPGPEGQEESTPQSDVTEDGESPE-DPSGTEGQLSEEEKPDQQPLSGEEELEPEAS----DGSGSWEDAALLTEANLPAPAPASASAPVLETLGSSEPAGGALRQRPTCSSS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13A935-1", "uniprot_id": "A0AB13A935_DANRE", "id": "A0AB13A935-1", "name": "", "aln": "-------------------------MGAAMGPLLLWLQDVAAVTLLRARRTLLRAAILLCVLVLLLWVSIFLYGSFYYSYMPSVSFSTPVHYYY-RTDCEASDAVLCSFPMANVSLLKNGRDQVMMSGQAYRISLELEMPESPVNEQLGMFMVKMSCYSNDGTVVHSVARSTMLHYRSNLLQTLSTLLFSPLLLSGVSEQKQLVEVELFPDLKLDIYHPAVGAVIEIQSRRVQIYSAQLRIHAYFTGVRFLLYNFPVMSAIVGVASNFTFLSVIVLFSYLQF-IWGGLYPPEQVRVKVMIGDSTRLQQRREEARKRMHSSASTPVMTYGRDGSELLSDPLQHPK-QTVRNKGDLDTPSVIGTEDLNNQQEDETDDAPVFLDAPRGAESSLTEEDADDKQRMAGERNDTQEEETAQPQSSDTSLRQRPGPWMRL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AC58H682-1", "uniprot_id": "A0AC58H682_DANRE", "id": "A0AC58H682-1", "name": "", "aln": "--------MQSSTEELNSEDSGVQDVGPQIRGLVVEILETMSDLLVWMRWKAVEMVIIICVILLVFWVALFLYGSFYYSFMPTANFVAPVNFFHSRTDCPSPHHPMCSFPMANVSLLKNGKHQVMTYGQPYQITLKLEMPESPTNQQLGMFLVTITPYSKAGQIIGVSSRSAMLHYRSSLLQTLGTLVFSPMFLSGMSEQKQSVTVELFSEFKDDSYKPTVGAMLEIHAPNIQIYKANLYIFAHFTGIRYLLYQFPLISALMGVMTNFTFLSLIIVLSFLQFNLNGRQFRRKRIRRKRGSMSKA---RMQQEEMDEIDDLFDDP---SEPHDRGIIPENVDTMDSNSADMEESIPDVTGEDSDDSRELTKDEPICE----DGN---EETILRRRHLSQDSLQAPQVLT--ETTDKN------YYRVGVCSSS-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V3X4-1", "uniprot_id": "BSCL2_DROME", "id": "Q9V3X4-1", "name": "Seipin", "aln": "MNILLRLIVFALDPLGLGRRFLIRPAVNLGWNVYDRVRSKADEKVGTVRELVLRLGLIAFAVVLIIWLAVFMYAAFYYVYMPAISHTRPVHMQF---KTCLETSTPCTFPHAHVSLTK--KQQLLMVGQAYKVIVNIDMPESPQNLELGMFMVCAEMRDYDSMLRGHSCRSAMMRYRSPLIRMISTWVLSPLYVLGWKEEFQQVPVEIFSRYLEERQHPITDVYVEIQSQKIQFYTVTLHIVADFTGLRYIMFNWPVLSAIVAISTNLFFILVVFLLSWYHW---SDAKWLHSVQIKYARLTKS---LEPGVIHSKASSLRDDDDDLVAYSDKSDIADVGGDTLSDVDADDLVLVKKSRSGKRESPDALRKRPTKK--------------TTADH--------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * :. :: .::*::*:::*:*.:*** :**: .. **: . . *:** *:*** * :.::: **.*:: :::::**** * :****:* . : .**.*::*** *:: :.* ::*.: : * *: * : **::. : * ... :*::: .:*:* . * * * ***:*::::::*: .*::.: :*: *: :: ::*: :: . . . : . :.: : . : . .. ", "identical_positions": 63, "similar_positions": 109, "identity": "14.55%" }, { "cls_id": "homologset.agr.MGI:1298393", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LP68-1", "uniprot_id": "A0ABK0LP68_RAT", "id": "A0ABK0LP68-1", "name": "SH3 and PX domain-containing protein 2A", "aln": "MLAYCVQDATVVDVEKRRNPSKHYVYIINVTWSDSTSQTIYRRYSKFFDLQMQLLDKFPIEGGQKDPKQRIIPFLPGKILFRRSHIRDVAVKRLKPINEYCRALVRLPPHISQCDEVFRFFEARPEDVNPPKEDYGSSKRKSVWLSSWAESPKKDVTGADTNAEPMILEQYVVVSNYKKQENSELSLQAGEVVDVIEKNESGWWFVSTSEEQGWVPATYLEAQNGTRDDSDINTSKTGEVSKRRKAHLRRLDRRWTLGGMVNRQHSREEKYVTVQPYTSQSKDEIGFEKGVTVEVIRKNLEGWWYIRYLGKEGWAPASYLKKAKDDLPT-------RKKNLAGPVEIIGSIMEISNLLNKKASGDKEAP--VEGEGS-------------------------------------EAPISKKEISLPILCN-------------ASNGSASGIPERTTSKLAQGSPAVARIAPQR---AQISSPNLRTRPPPRRESSLGFQLPKPPEPPSVEVEYYTIAEFQSCISDGISFRGGQKAEVIDKNSGGWWYVQIGEKEGWAPASYIDKRKKPNLSRRTSTLTRPKVPPPAPPGKPKETEENP--AGACENQGSPLKLKYEEPEYDIPAFGFDSEPELNEEPTEDRGSGDKHP---------------AQPRRTSPASSLQRAHFKVGESSEDVALEEETIYENEGFRPYTEDTLSARGSSGDSDSPGNSSLSLAMKNSPKSDSPKSSSLLKLKAEKNAQAELGKNQSNISFSSSVTIGTTS--SSSSSSSSLSKNSGDLKPRSASDAGIRDSPKGGTKKDPDVKTGLASCVRAKPSVRPKPVLNRAESQSQEKMDISSLRRQLRPTGQLR-GGLKGSRSEDSELPPQTASE----GSRRGSADIIPLPATTPPCVPKKEWEGQGTAYVTCSAYQKVQDSEISFPAGAEVHVLEKVESGWWYVRFGELEGWAPSHYLVPEENQQPDPDSKEPDTV--KSTQNEGKSDSLEKIEKRVQALNTVNQS-----KRATPPIPSKPPGGFGKTSGTV---AVKMRNGVRQVAVRPQSVFVSPPP---KDNNLSCALRRNESLTATDSVR---GVRRNSSFSTAR-SAAAEAKGRLAERAASQGSESPLLPTQRNGIPVSPVRPKPIEKSQFIHNNLKDVYVSIADYEGDEETAGFQEGVSMEVLERNPNGWWYCQILDEVKPFKGWVPSNYLEKKN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O89032-1", "uniprot_id": "SPD2A_MOUSE", "id": "O89032-1", "name": "SH3 and PX domain-containing protein 2A", "aln": "MLAYCVQDATVVDVEKRRSPSKHYVYIINVTWSDSTSQTIYRRYSKFFDLQMQLLDKFPIEGGQKDPKQRIIPFLPGKILFRRSHIRDVAVKRLKPIDEYCRALVRLPPHISQCDEVFRFFEARPEDVNPPKEDYGSSKRKSVWLSSWAESPKKDVTGADTNAEPMILEQYVVVSNYKKQENSELSLQAGEVVDVIEKNESGWWFVSTSEEQGWVPATYLEAQNGTRDDSDINTSKTGEVSKRRKAHLRRLDRRWTLGGMVNRQHSREEKYVTVQPYTSQSKDEIGFEKGVTVEVIRKNLEGWWYIRYLGKEGWAPASYLKKAKDDLPT-------RKKNLAGPVEIIGNIMEISNLLNKKASGDKEAP--AEGEGS-------------------------------------EAPITKKEISLPILCN-------------ASNGSALAIPERTTSKLAQGSPAVARIAPQR---AQISSPNLRTRPPPRRESSLGFQLPKPPEPPSVEVEYYTIAEFQSCISDGISFRGGQKAEVIDKNSGGWWYVQIGEKEGWAPASYIDKRKKPNLSRRTSTLTRPKVPPPAPPSKPKEAEENP--VGACESQGSPLKVKYEEPEYDVPAFGFDSEPEMNEEPSGDRGSGDKHP---------------AQPRRISPASSLQRAHFKVGESSEDVALEEETIYENEGFRPYTEDTLSARGSSGDSDSPGSSSLSLAVKNSPKSDSPKSSSLLKLKAEKNAQAELGKNQSNISFSSSVTISTTC--SSSSSSSSLSKNNGDLKPRSASDAGIRDTPKVGTKKDPDVKAGLASCARAKPSVRPKPVLNRAESQSQEKMDISSLRRQLRPTGQLR-GGLKGSRSEDSELPPQMASE----GSRRGSADIIPLTATTPPCVPKKEWEGQGATYVTCSAYQKVQDSEISFPEGAEVHVLEKAESGWWYVRFGELEGWAPSHYLVAEENQQPDTASKEGDTG--KSSQNEGKSDSLEKIEKRVQALNTVNQS-----KRATPPIPSKPPGGFGKTSGTV---AVKMRNGVRQVAVRPQSVFVSPPP---KDNNLSCALRRNESLTATDSLR---GVRRNSSFSTAR-SAAAEAKGRLAERAASQGSESPLLPTQRKGIPVSPVRPKPIEKSQFIHNNLKDVYISIADYEGDEETAGFQEGVSMEVLEKNPNGWWYCQILDEVKPFKGWVPSNYLEKKN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5TCZ1-1", "uniprot_id": "SPD2A_HUMAN", "id": "Q5TCZ1-1", "name": "SH3 and PX domain-containing protein 2A", "aln": "MLAYCVQDATVVDVEKRRNPSKHYVYIINVTWSDSTSQTIYRRYSKFFDLQMQLLDKFPIEGGQKDPKQRIIPFLPGKILFRRSHIRDVAVKRLKPIDEYCRALVRLPPHISQCDEVFRFFEARPEDVNPPKEDYGSSKRKSVWLSSWAESPKKDVTGADATAEPMILEQYVVVSNYKKQENSELSLQAGEVVDVIEKNESGWWFVSTSEEQGWVPATYLEAQNGTRDDSDINTSKTGEVSKRRKAHLRRLDRRWTLGGMVNRQHSREEKYVTVQPYTSQSKDEIGFEKGVTVEVIRKNLEGWWYIRYLGKEGWAPASYLKKAKDDLPT-------RKKNLAGPVEIIGNIMEISNLLNKKASGDKETPP-AEGEGH-------------------------------------EAPIAKKEISLPILCN-------------ASNGSAVGVPDRTVSRLAQGSPAVARIAPQR---AQISSPNLRTRPPPRRESSLGFQLPKPPEPPSVEVEYYTIAEFQSCISDGISFRGGQKAEVIDKNSGGWWYVQIGEKEGWAPASYIDKRKKPNLSRRTSTLTRPKVPPPAPPSKPKEAEEGP--TGASESQDSPRKLKYEEPEYDIPAFGFDSEPELSEEPVEDRASGERRP---------------AQPHRPSPASSLQRARFKVGESSEDVALEEETIYENEGFRPYAEDTLSARGSSGDSDSPGSSSLSLTRKNSPKSGSPKSSSLLKLKAEKNAQAEMGKNHSSASFSSSITINTTCCSSSSSSSSSLSKTSGDLKPRSASDAGIRGTPKVRAKKDADANAGLTSCPRAKPSVRPKPFLNRAESQSQEKMDISTLRRQLRPTGQLR-GGLKGSKSEDSELPPQTASEAPSEGSRRSSSDLITLPATTPPCPTKKEWEGPATSYMTCSAYQKVQDSEISFPAGVEVQVLEKQESGWWYVRFGELEGWAPSHYLVLDENEQPDPSGKELDTVPAKGRQNEGKSDSLEKIERRVQALNTVNQS-----KKATPPIPSKPPGGFGKTSGTP---AVKMRNGVRQVAVRPQSVFVSPPP---KDNNLSCALRRNESLTATDGLR---GVRRNSSFSTAR-SAAAEAKGRLAERAASQGSDSPLLPAQRNSIPVSPVRPKPIEKSQFIHNNLKDVYVSIADYEGDEETAGFQEGVSMEVLERNPNGWWYCQILDGVKPFKGWVPSNYLEKKN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LYG0-1", "uniprot_id": "SPD2A_DANRE", "id": "Q1LYG0-1", "name": "SH3 and PX domain-containing protein 2A", "aln": "MQFRTVLDVKVVDVEKRRNPSKHYVYLINVTYSDSTSHIIYRRYSKFFDLQMQILDKFPIEGGQKDPKKRIIPFLPGKILFRRSHVRDVAMKRLRFIDDYCRALVRLPPQISQSEEVLRFFETKPDDINPPVEDYGS-KRK---------------SGLDS-SEPMVLEQYVVVANYERQENSEISLKAGETVDVIEKSESGWWFVSTAEEQGWVPATYLDSQSGTRDDLDLGTSRSGEVTKRRKAHLKRLDRRWTLGGIVNRQQSREEKYVSVQAYASQGKDEIGFEKGVTVEVIQKNLEGWWYIRYQGKEGWAPASYLKKLKDDLSP-------RKKTLTGPVEIIGNIMEISNLLNKKAVSEKDIQTDGEATTP-------------------------------------ERHISKSEISLPMPYAPEAGVAPTVVTALGMNSGSSATLQENKSRAEPGSPAIARVAPHR---VEIGSPNLRQKPPPRRDANLAFQLPKPPEAPTVEAEYYTIAEFQSSISDGISFRGGQKADVIEKNSGGWWYVQIGDTEGWAPSSYIDKRKKPNLSRRTSTLTRPKVPPPAPPVKKQDSEEGPSLGGSASKAPESPQRVYEEPEYDVPALGFDSELDCNPPKPKTHNSPKPEPRKFEIKSNPAAAERIAQAGKASPLLKVMTSPLRKRNSLENIN-KEEVIYENEGFRFSSDDFASG------CDSHTPRSLTLGRK-PFGSSSGGGKPLRKVSPDLNRSHSLGR--------------------AERHSSKLFSDESARNPK----------REPVMRKDVEIRIGQSPLARPKPVVRPKPLLTKSEPQSPERMDISSIRRHLRPTGSLRQGAIRAMRGEDSETASVVSSE-----DSTSSRSTSDLSSVYSKGSRGGESDHESVLFRTTDAYERAQESELSFPAGVEVEVLEKQESGWWFVRWGSDEGWVPTFYLEPIKHTHNVGIQESRDSP-LVDLGSTNKSNSLEKNEQRVQALNNLNQQNLRSMSNPSPPIPSKPPGGFSKPTAMLNGSSVRMRNGVRQAAVRPQSVFVSPPQPLKETNIHTGSLRRNESLGAGDHLRSTGGVRRNSSFTAVRPQPVTDVRVRAGTTITAPAGSSSPLIAQRNGIPISTVRPKPIEKMQLIHNNLREVYVSIADYRGDEETMGFSEGTSLEVLEKNPNGWWYCQVLDGLQGRKGWVPSNYLERKK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0ACD6B726-1", "uniprot_id": "A0ACD6B726_DANRE", "id": "A0ACD6B726-1", "name": "", "aln": "---------------------------------------MARRSS----------------GGHG----------------------------------------RGGSWLTAC-----FFPS------------SSGKER-----------------GEALGAEDCMCVYAVTADYQRQENTEISLKAGERVEVIEKSESGWWFVRTAEEQGWVPATYLVSLTGRRDSHRAPNGET-------------------------------EWYITVQPFSSSSQDELGFESGVIVEVIQRNLEGWWFIRYGGKEGWAPAAYLKKIQDGVTASNQPAESNKASVQGQVEIIGNLMEISNLLNKKPANERHSHTQTDSHSANTYRNSQTDSYTQYSGDEDQTEVNTERDSEDQIKTHIETSVSDSSGSVSVSDACVS--------AVATELCVSSTVSSFKAKTVPASPAIARVAPQRFHSVENKPPSNNLKPPPRRENSLGFQLPQPPDPPTVEAEYYTIAEFRSCLTDGISFSGGQRADVIEKNSGGWWYVQIGEKEGWAPCSYIDKRKKPTLNRQTSTLTRPKVPPPAPPIKKQNSLP----CVESEIMTTTYPRVYEEPEYDVPTIGFEFDPDLDFFPS-------------------------DAPTKATPPLCQRTVSFTLGDEE-----DDEGVYANGGFRAVP-------------HCKDNHSPSSAHRASMWDPPEYDAPTIEPSFETN--------------------------------TTLYAQSN----------------QPKLKQQADE-------SKSKPSVRPKPTN----------QDCSSLR-----------------KPQNQEQPSHMQFR----TSRTSEESDTGLSDDFQSCLS----DSSSFLYRTTAAYQQEEPCELSFPAGVQVEVVEKKESGWWFVRWGNEEGWAPTYYLQPIKSSSETSSLEAKTTEKINSELSWSASPELEISVQVDSGKMGKSVS----LEKNEQRVNQSLKGGLRS----------NSRVGVKQLAVRPQNVLKDNTN-----AHAAPAGRRNDTLPS------------HSSLVSYN-----------DQSSSSHAGNT---ESMRRKVPVSMVKPKP----HLIHNNLREEYVSIADYRGDAETMSFPAGTRLEVLERNPNGWWYCRVLDTTKTRKGWVPSNFLERKS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ** * **: * . :: . ** : .* *.: :: . : *.*.::*::***:*:**:*** *:****.******* *:*********** : .* **. ...: * *::**.::*..:**:***.** ****::******:*** ********:**** :*.:.. .* .: * *****.:**********. .::. :. * ::... *:.: . : . . :: .***:**:**:* .: .*. . :*****: .*.****:**:.*:**.********:*.::***** ***:*:**:************:.*****.*********.*.*:*************** * ::: .. . *******:*::**: : : . . : :* : :. .:* :* * *** . .. * : : . . . . . : . : * :.* .. : ::: : :.** ***** * *::* : ::.* .. . . .. . *. : . : * **:: : .*:*** *.:*.*:** *****:**:*. ***.*:.** : : : . . . * .** : .. . . .. : .. **: . . * **:* *****.*: . . : : ***::* : :**: : . :: ...: : *. :*:* *:*** ::*****:: *:*****.** ** .* *. :****:********::** : *******:**:*.", "identical_positions": 321, "similar_positions": 248, "identity": "26.16%" }, { "cls_id": "homologset.agr.MGI:1298395", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9H0U9-1", "uniprot_id": "TSYL1_HUMAN", "id": "Q9H0U9-1", "name": "Testis-specific Y-encoded-like protein 1", "aln": "MSGLDGVKRTTPLQTHSIIISDQVPSDQDAHQYLRLRDQSEATQVMAEPGEGGSETVALPPPPPSEEGGVPQDAAGRGGTPQIRVVGGRGHVAIKAGQEEGQPPAEGLAAASVVMAADRSLKKGVQGGEKALEICGAQRSASELTAGAEAEAEEVKTGKCATVSAAVAERESAEVVKEGLAEKEVMEEQMEVEEQPPEGEEIEVAEEDRLEEEAREEEGP----WPLHEALRMDPLEAIQLELDTVNAQADRAFQQLEHKFGRMRRHYLERRNYIIQNIPGFWMTAFRNHPQLSAMIRGQDAEMLRYITNLEVKELRHPRTGCKFKFFFRRNPYFRNKLIVKEYEVRSSGR------VVSLSTPIIWRRG--------HEPQSFIRRNQDLICSFFTWFSDHSLPESDKIAEIIKEDLWPNPLQYYLLREGVRRARRRPLREPVEIPRPFGFQSG---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O88852-1", "uniprot_id": "TSYL1_MOUSE", "id": "O88852-1", "name": "Testis-specific Y-encoded-like protein 1", "aln": "MSSPERDEGTPVPDSRGHCDADTVSGTPDRRPLLGEEK--------AVTGEGRAGIVGSP---------APRDVEG--LVPQIRVAAAR--------QGESPPSVRGPAAA--VFVTPKYVEK------------------AQETRGAESQARDVKT-EPGTVAAAAEK---SEVATPG------SEEVMEVE-QKPAGEEMEMLEASGGVREAPEEAGP----WHLGIDLRRNPLEAIQLELDTVNAQADRAFQHLEQKFGRMRRHYLERRNYIIQNIPGFWMTAFRNHPQLSAMIRGRDAEMLRYVTSLEVKELRHPKTGCKFKFFFRRNPYFRNKLIVKEYEVRSSGR------VVSLSTPIIWRRG--------HEPQSFIRRNQDLICSFFTWFSDHSLPESDRIAEIIKEDLWPNPLQYYLCREGIRRPRRRPIREPVEIPRPFGFQSG---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N831-1", "uniprot_id": "TSYL6_HUMAN", "id": "Q8N831-1", "name": "Testis-specific Y-encoded-like protein 6", "aln": "MSLPE---SPHSPATLDYALEDPHQGQRSREKSKATEV-------MADMFDGRLEPIVFPPPRLPEEGVAPQDPADGGHTFHILVDAGRSHGAIKAGQEVTPPPAEGLEAASASLTTDGSLKNG---------------FPGEETHGLGGEKALETCGAGRSESEVIAEGKAEDVKPEE------CAMFSAPVDEKPGGEEMDVAEENRAIDEVNREAGPGPGPGPLNVGLHLNPLESIQLELDSVNAEADRALLQVERRFGQIHEYYLEQRNDIIRNIPGFWVTAFRHHPQLSAMIRGQDAEMLSYLTNLEVKELRHPRTGCKFKFFFQRNPYFRNKLIVKVYEVRSFGQ------VVSFSTLIMWRRG--------HGPQSFIHRNRHVICSFFTWFSDHSLPESDRIAQIIKEDLWSNPLQYYLLGEDAHRARRRLVREPVEIPRPFGFQCG---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P53997-1", "uniprot_id": "SET_DROME", "id": "P53997-1", "name": "Protein SET", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSVPKRAKLDGAPADGNTSAAAGNNEE--------ESEALEQIDACQNEIDALNEKASEEILKVEQKYNKLRKPCYEKRSELVKRIPNFWVTSFINHPQVSGILDEEEEECLHALNKLEVEEFEDIKSGYRINFHFDENPYFENKVLTKEFHLNSAAASENGDWPASTSTPIKWKEGKNLLKLLLTKPYGNKKKRNSEYKTFFDWFSDNTDPVNDEIAELIKDDLWPNPLQYYLVPDIEVEPEDEEDNEDNDE-EAFDDEDGEDGEGEEEEEDEDDK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * ::: . . : : ::: * *:*::* :*.. : ::*:::.:::. *:*. :::.**.**:*:* :***:*.:: .: * * :..***:*:.. ::* :::*.* .****.**::.* :.:.* . .* ** * *:.* * . ::.. :** ****:: * .*.**::**:***.******* : ... . .* : ..*. : * ", "identical_positions": 68, "similar_positions": 95, "identity": "14.47%" }, { "cls_id": "homologset.agr.MGI:1298397", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63544-1", "uniprot_id": "SYUG_RAT", "id": "Q63544-1", "name": "Gamma-synuclein", "aln": "MDVFKKGFSIAREGVVGAVEKTKQGVTEAAEKTKEGVMYVGTKTKGERGTSVTSVAEKTKEQANAVSEAVVSSVNTVATKTVEEAENIVVTTGVVRKEDLEPPAQDQE---AKEQEE-GEEAKSGGD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z0F7-1", "uniprot_id": "SYUG_MOUSE", "id": "Q9Z0F7-1", "name": "Gamma-synuclein", "aln": "MDVFKKGFSIAKEGVVGAVEKTKQGVTEAAEKTKEGVMYVGTKTKENVVQSVTSVAEKTKEQANAVSEAVVSSVNTVANKTVEEAENIVVTTGVVRKEDLEPPAQDQE---AKEQEE-NEEAKSGED", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O76070-1", "uniprot_id": "SYUG_HUMAN", "id": "O76070-1", "name": "Gamma-synuclein", "aln": "MDVFKKGFSIAKEGVVGAVEKTKQGVTEAAEKTKEGVMYVGAKTKENVVQSVTSVAEKTKEQANAVSEAVVSSVNTVATKTVEEAENIAVTSGVVRKEDLRPSAPQQEGEASKEKEEVAEEAQSGGD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PWC8-1", "uniprot_id": "A0A8M9PWC8_DANRE", "id": "A0A8M9PWC8-1", "name": "", "aln": "MDVLMKGFSMAKEGVVAAAEKTKAGVEEAALKTKEGVMYVGNKTKEGMVSGVNTVVQKTTDQANIVGETAVGGANVAGQNTVEGLENVAASTGMVN-----PDEALYEGDFSHGGME-GGEGGEGY-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***: ****:*:****.*.**** ** *** ********** *** .*.:*.:**.:*** *.*:.*...*... :*** **:..::*:*. * * :: * *. .* ", "identical_positions": 58, "similar_positions": 33, "identity": "45.67%" }, { "cls_id": "homologset.agr.MGI:1298398", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q61881-1", "uniprot_id": "MCM7_MOUSE", "id": "Q61881-1", "name": "DNA replication licensing factor MCM7", "aln": "--------MALKDYAIEKEKVKKFLQEFYYE----------------------NELGKKQFKYGTQLVHLAHREQVALYVDLDDIAEDDPE----------LVDSICENAKRYSRLFGDVVQELLPEYKEKEVVNKDVLDVYIEHR-----LMMEQRS------------RDP---------GAVRNPQNQYPSELMRRFELYFRGPSS------------SKPRVIREVRADSVGKLLTVRGIVTRVSEVKPRMVVATYTCDQCGAETYQPIQSPTFMPLIMCPSQECQTNRSGGRLYLQTRGSKFVKFQEMKIQEHSDQVPVGNIPRSITVVLEGENTRIAQPGDHVSVTGIFLPVLRTGFQQMAQGLLSETYLEAHWIVKMTKSDDDVSGAGELSSEELKQIAEEDFYEKLAASIAPEIYGHEDVKKALLLLLVGGVDQSP-QGMKIRGNIHICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVGLTAAVLRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAYGRYNPRRSLEQNVQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHITYVHQHSRQPPAQFEPLDMKLMRRYIAMCHERQPTVPESLADYITAAYVEMRREARASKDATYTS----ARTLLAILRLSTALARLRMVDIVEKEDVNEAIRLMEMSKDSL-LGEKGQTARTQRPADVIFATIRELVSRG--RSVHFSEAEQRCISRGFTPAQFQAALDEYEELNVWQVNTSRTRITFV-----------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P33993-1", "uniprot_id": "MCM7_HUMAN", "id": "P33993-1", "name": "DNA replication licensing factor MCM7", "aln": "--------MALKDYALEKEKVKKFLQEFYQD----------------------DELGKKQFKYGNQLVRLAHREQVALYVDLDDVAEDDPE----------LVDSICENARRYAKLFADAVQELLPQYKEREVVNKDVLDVYIEHR-----LMMEQRS------------RDP---------GMVRSPQNQYPAELMRRFELYFQGPSS------------NKPRVIREVRADSVGKLVTVRGIVTRVSEVKPKMVVATYTCDQCGAETYQPIQSPTFMPLIMCPSQECQTNRSGGRLYLQTRGSRFIKFQEMKMQEHSDQVPVGNIPRSITVLVEGENTRIAQPGDHVSVTGIFLPILRTGFRQVVQGLLSETYLEAHRIVKMNKSEDDESGAGELTREELRQIAEEDFYEKLAASIAPEIYGHEDVKKALLLLLVGGVDQSP-RGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVGLTAAVLRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAYGRYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHITYVHQHSRQPPSQFEPLDMKLMRRYIAMCREKQPMVPESLADYITAAYVEMRREAWASKDATYTS----ARTLLAILRLSTALARLRMVDVVEKEDVNEAIRLMEMSKDSL-LGDKGQTARTQRPADVIFATVRELVSGG--RSVRFSEAEQRCVSRGFTPAQFQAALDEYEELNVWQVNASRTRITFV-----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9XYU0-1", "uniprot_id": "MCM7_DROME", "id": "Q9XYU0-1", "name": "DNA replication licensing factor Mcm7", "aln": "--------MARRDYAQDRESIKTFLSEFCKC----------------------DDDGKKEFVYGSQLVKLAHREQVLITIDLDDLAEFNES----------LAEAVVDNCRRYTSIFSDVIAELLPSYKQQEVHAKDALDVYIEHR-----LMMESRT------------RNP---------MEQRDERNSFPSELMKRFEVGFKPLST------------EKAHSIREVKAQHIGKLVTVRGIVTRCTEVKPMMVVATYTCDRCGSETYQPVNSLSFTPVHDCPSDDCRVNKAGGRLYLQTRGSKFVKFQEVKMQEHSDQVPVGHIPRSMTIMCRGEVTRMAQPGDHIVVSGVFLPLMRTGFAQMIQGLLSETFLQAHRIICINKNDEISDKDAELTPEELEELAQDDFYERLATSLAPEIYGHLDVKKALLLLLVGGVDKRP-DGMKIRGNINICLMGDPGVAKSQLLGYISRLAVRSQYTTGRGSSGVGLTAAVMKDPLTGEMTLEGGALVLADQGVCCIDEFDKMADQDRTAIHEVMEQQTISIAKAGIMTTLNARVSILAAANPAFGRYNPRRTVEQNIQLPAALLSRFDLLWLIQDKPDRDNDLRLAKHITYVHSHSKQPPTRVKALDMNLMRRYINLCKRKNPTIPDELTDYIVGAYVELRREARNQKDMTFTS----ARNLLGILRLSTALARLRLSDSVEKDDVAEALRLLEMSKDSLNQIHEHQKGHVPNTSDRIFAIVRELAGSG--KAVKISDIMDRCTTKGFKPDQVDKCIDDYEELNVWQVNMGRTKITFM-----------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38132-1", "uniprot_id": "MCM7_YEAST", "id": "P38132-1", "name": "DNA replication licensing factor MCM7", "aln": "MSAALPSIQLPVDYNNLFNEITDFLVTFKQDTLSSDATRNENEDENLDAENIEQHLLEKGPKYMAMLQKVANRELNSVIIDLDDILQYQNEKFLQGTQADDLVSAIQQNANHFTELFCRAIDNNMPLPTKEIDYKDDVLDVILNQRRLRNERMLSDRTNEIRSENLMDTTMDPPSSMNDALREVVEDETELFPPNLTRRYFLYFKPLSQNCARRYRKKAISSKPLSVRQIKGDFLGQLITVRGIITRVSDVKPAVEVIAYTCDQCGYEVFQEVNSRTFTPLSECTSEECSQNQTKGQLFMSTRASKFSAFQECKIQELSQQVPVGHIPRSLNIHVNGTLVRSLSPGDIVDVTGIFLPAPYTGFKALKAGLLTETYLEAQFVRQHKKKFASFSLTSDVEERVMELITSGDVYNRLAKSIAPEIYGNLDVKKALLLLLVGGVDKRVGDGMKIRGDINVCLMGDPGVAKSQLLKAICKISPRGVYTTGKGSSGVGLTAAVMKDPVTDEMILEGGALVLADNGICCIDEFDKMDESDRTAIHEVMEQQTISISKAGINTTLNARTSILAAANPLYGRYNPRLSPLDNINLPAALLSRFDILFLMLDIPSRDDDEKLAEHVTYVHMHNKQPDLDFTPVEPSKMREYIAYAKTKRPVMSEAVNDYVVQAYIRLRQDSKREMDSKFSFGQATPRTLLGIIRLSQALAKLRLADMVDIDDVEEALRLVRVSKESL-YQETNKSKEDESPTTKIFTIIKKMLQETGKNTLSYENIVKTVRLRGFTMLQLSNCIQEYSYLNVWHLINEGNTLKFVDDGTMDTDQEDSLVSTPKLAPQTTASANVSAQDSDIDLQDA", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** :.:. ** * :. :* * * ::*:** : :****: : : . *..:: :*..::: :* .: : :* .:. .*.*** :::* *:..*: :* .. : :*.:* :*: : *: * .*. :*:::.: :*:*:*****:** ::*** : * :****:** *.:* ::* :* *: *.*::* *:: *:*::.**.*:* *** *:** *:*****:****:.: .* .* .*** : *:*:*** *** : ***:**:*:*: : .*. . .:: . :. ::. *.*::** *:******: ***************: ******:*::************** * ::: *. ****:***********::*.::.*: **********:*:********* : ****************:**** ****** ******** :****** : :*::**********:*:*: * *.**:* :**:*:**** *.:** . .:: . **.** .: :.* :.: : **:. **:.:*::: . * .:: .*.**.*:*** ***:**: * *: :** **:**:.:**:** . :. . .: **: :::: .:: .: . :**. *.. .:::*. ****:: . :.*: ", "identical_positions": 305, "similar_positions": 229, "identity": "36.05%" }, { "cls_id": "homologset.agr.MGI:1298405", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q96CW1-1", "uniprot_id": "AP2M1_HUMAN", "id": "Q96CW1-1", "name": "AP-2 complex subunit mu", "aln": "MIGGLFIYNHKGEVLISRVYRDDIGRNAVDAFRVNVIHARQQVRSPVTNIARTSFFHVKR---SNIWLAAVTKQNVNAAMVFEFLYKMCDVMAAYFGKISEENIKNNFVLIYELLDEILD-FGYPQNSETGALKTFITQQGIKSQHQTKEEQ-------------------------SQITSQVTG------------QIGWRREGIKYRRNELFLDVLESVNLLMSPQGQVLSAHVSGRVVMKSYLSGMPECKFGMNDKIVIEKQGKG----TADETS-----------KSGKQSIAIDDCTFHQCVRLSKFDSERSISFIPPDGEFELMRYRTTKDIILPFRVIPLVREVGR-TKLEVKVVIKSNFKPSLLAQKIEVRIPTPLNTSGVQVICMKGKAKYKASENAIVWKIKRMAGMKESQISAEIELLPTNDKK---KWARPPISMNFEVPFAP-SGLKVRYLKVFEPKLNYSDHDVIKWVRYIGRSGIYETRC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P84091-1", "uniprot_id": "AP2M1_MOUSE", "id": "P84091-1", "name": "AP-2 complex subunit mu", "aln": "MIGGLFIYNHKGEVLISRVYRDDIGRNAVDAFRVNVIHARQQVRSPVTNIARTSFFHVKR---SNIWLAAVTKQNVNAAMVFEFLYKMCDVMAAYFGKISEENIKNNFVLIYELLDEILD-FGYPQNSETGALKTFITQQGIKSQHQTKEEQ-------------------------SQITSQVTG------------QIGWRREGIKYRRNELFLDVLESVNLLMSPQGQVLSAHVSGRVVMKSYLSGMPECKFGMNDKIVIEKQGKG----TADETS-----------KSGKQSIAIDDCTFHQCVRLSKFDSERSISFIPPDGEFELMRYRTTKDIILPFRVIPLVREVGR-TKLEVKVVIKSNFKPSLLAQKIEVRIPTPLNTSGVQVICMKGKAKYKASENAIVWKIKRMAGMKESQISAEIELLPTNDKK---KWARPPISMNFEVPFAP-SGLKVRYLKVFEPKLNYSDHDVIKWVRYIGRSGIYETRC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P84092-1", "uniprot_id": "AP2M1_RAT", "id": "P84092-1", "name": "AP-2 complex subunit mu", "aln": "MIGGLFIYNHKGEVLISRVYRDDIGRNAVDAFRVNVIHARQQVRSPVTNIARTSFFHVKR---SNIWLAAVTKQNVNAAMVFEFLYKMCDVMAAYFGKISEENIKNNFVLIYELLDEILD-FGYPQNSETGALKTFITQQGIKSQHQTKEEQ-------------------------SQITSQVTG------------QIGWRREGIKYRRNELFLDVLESVNLLMSPQGQVLSAHVSGRVVMKSYLSGMPECKFGMNDKIVIEKQGKG----TADETS-----------KSGKQSIAIDDCTFHQCVRLSKFDSERSISFIPPDGEFELMRYRTTKDIILPFRVIPLVREVGR-TKLEVKVVIKSNFKPSLLAQKIEVRIPTPLNTSGVQVICMKGKAKYKASENAIVWKIKRMAGMKESQISAEIELLPTNDKK---KWARPPISMNFEVPFAP-SGLKVRYLKVFEPKLNYSDHDVIKWVRYIGRSGIYETRC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7ZW98-1", "uniprot_id": "AP2MB_DANRE", "id": "Q7ZW98-1", "name": "AP-2 complex subunit mu-B", "aln": "MIGGLFIYNHKGEVLISRVYRDDIGRNAVDAFRVNVIHARQQVRSPVTNIARTSFFHVKR---SNIWLAAVTKQNVNAAMVFEFLYKMCDVMTAYFGKISEENIKNNFVLIYELLDEILD-FGYPQNSETGALKTFITQQGIKSQHLTKEEQ-------------------------SQITSQVTG------------QIGWRREGIKYRRNELFLDVLESVNLLMSPQGQVLSAHVSGRVVMKSYLSGMPECKFGMNDKIVIDKQGKGG---TTDDTG-----------KSGKQSIAIDDCTFHQCVRLSKFDSERSISFIPPDGEYELMRYRTTKDIILPFRVIPLVREVGR-TKLEVKVVIKSNFKPSLLAQKIEVRIPTPLNTSGVQVICMKGKAKYKASENAIVWKIKRMVGMKESQISAEIELLPTNDKK---KWARPPISMNFEVPFAP-SGLKVRYLKVFEPKLNYSDHDVIKWVRYIGRSGIYETRC", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6NWK2-1", "uniprot_id": "AP2MA_DANRE", "id": "Q6NWK2-1", "name": "AP-2 complex subunit mu-A", "aln": "MIGGLFIYNHKGEVLISRVYRDDIGRNAVDAFRVNVIHARQQVRSPVTNIARTSFFHVKR---SNIWLAAVTKQNVNAAMVFEFLYKMCDVMTAYFGKISEENIKNNFVLIYELLDEILD-FGYPQNSETGALKTFITQQGIKGQHQTKEEQ-------------------------SQITSQVTG------------QIGWRREGIKYRRNELFLDVLESVNLLMSPQGQVLSAHVSGRVVMKSYLSGMPECKFGMNDKIVIDKQGKGG---TTDDAG-----------KSGKQSIAIDDCTFHQCVRLSKFDSERSISFIPPDGEYELMRYRTTKDIILPFRVIPLVREVGR-TKLEVKVVIKSNFKPSLLAQKIEVRIPTPLNTSGVQVICMKGKAKYKASENAIVWKIKRMAGMKESQISAEIELLPTNDKK---KWARPPISMNFEVPFAP-SGLKVRYLKVFESKLNYSDHDVIKWVRYIGRSGIYETRC", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O62530-1", "uniprot_id": "O62530_DROME", "id": "O62530-1", "name": "", "aln": "MIGGLFVYNHKGEVLISRVYRDDIGRNAVDAFRVNVIHARQQVRSPVTNIARTSFFHIKR---ANIWLAAVTKQNVNAAMVFEFLLKIIEVMQSYFGKISEENIKNNFVLIYELLDEILD-FGYPQNTDSGTLKTFITQQGIKS--ATKEEQ-------------------------MQITSQVTG------------QIGWRREGIKYRRNELFLDVLEYVNLLMSPQGQVLSAHVAGKVVMKSYLSGMPECKFGINDKIVMESKGRGLSGNSEAETS-----------RSGKPVVVIDDCQFHQCVKLSKFETEHSISFIPPDGEFELMRYRTTKDISLPFRVIPLVREVGR-TKMEVKVVLKSNFKPSLLGQKIEVKIPTPLNTSGVQLICLKGKAKYKASENAIVWKIKRMAGMKETQLSAEIELLETDTKK---KWTRPPISMNFEVPFAP-SGFKVRYLKVFEPKLNYSDHDVVKWVRYIGRSGLYETRC", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q99186-1", "uniprot_id": "AP2M_YEAST", "id": "Q99186-1", "name": "AP-2 complex subunit mu", "aln": "MISGVLVYSSRGELVLNKFFKNSLKRSISDIFRVQVINN-LDVRSPVLTLGSTTFHHIRSRHGDNLWLVTITRSNANSAAIWEFLYKLDAVMNAYR-LDREEALKEEFMIVHEMLDIMLGGNGIPIDTELNSVIAQMSVKPVRNMGGLLDSPDGNDVLSSSSSPTSSAGELHFPKFLTKRSSSFLGQGDSTSDFYDNNKITWRPKGIIHKKDEVFLYVNERINILVSRDGSILKSYVDGTIDITTHLSGTPICRFGLNDSLGMQSEDEKKWLAQQQRHSGSDFGNKNFIPKAAAGSVLLEDCKFHECVSLDKFNRNHIIEFVPPDGSMELMKYHVRDNINLPFKVTPIVTHSTRDNEIDYRITLKSLFPGKLSAKDVVLHIPVPPSTVDCKISVSNGHCKFVPEENAMIWRFNKYNGLTENTLSAVTVSTSDTTQLNLQQWTRPPISLEFEVMMFSNSGLVVRYFTISG---KDSKHRAVKWIKYISKAGSYEVRY", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.*:::*. :**:::.:.:::.: *. * ***:**: :***** .:. *:*.*:: *:**.::*:.*.*:* ::*** *: ** :* ** :*::*::::*:** :*. * * ::: .:: : :: : ::. :. : :*.. * :* ** :** ::::*:** * * :*:*:* :*.:*.::* * : :.::*** * *:**:**.: ::.:.. . ::. : ::** **:** *.**: :: *.*:****. ***:*:. .:* ***:* *:* . * .::: ::.:** * .* .:.: ::**.* .* . :: :*:.*: ..***::*:::: *:.*. :** : :*:*****::*** : . **: ***:.: : *.* .:**::**.::* **.* ", "identical_positions": 142, "similar_positions": 180, "identity": "28.63%" }, { "cls_id": "homologset.agr.MGI:1298406", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8N7UY30-1", "uniprot_id": "A0A8N7UY30_DANRE", "id": "A0A8N7UY30-1", "name": "", "aln": "----MALTRTHVLRSWIFFSVFLCCWIFTNGQIVYSISEEANPGTAVGNLAKDFNLNVQDIERRGFQIVSESNKRYFDFNFKTGVLHVKERIDREELCEQKIKCSLPLEAIVNSPLNVFRFEINVLDINDNPPKFRTPKTTINISESALPGEQFALPSAFDADVGINSVKSYKLSPNEHFSLDVQSGGEQSVSAELVLQKALDREKQPLIRLTLTAVDGGKPLRSGTMQITVHVEDVNDNIPVFSKSLYKARVNENAPPGTSIITVQASDPDEGVNGQIVYALVNHD-NDRNVESFAINPETGEITVKGDVDYERKNAVELRVQAKDKGHKPRAALCKVLLEIIDVNDNVPEISVTSLVNTVKEDALIDTVVGMITVTDNDAGKNGQVILNIQGSSPFKVQNS-YKNYYTLFVNGPLDRERASEYNVTISAADEGTPPLSSTSVIAVHVSDVNDNAPRFPEPVINVYVKENSQIGAVLHTVSAVDPDVGDNARITYSLLE-SSKSGPVTSMININSDTGDLHSLQSFNYEEIKTFEFKVQATDSGVPPLSSNVTVNVFVLDENDNSPAILAPYSELGSVN-TENIPYSAEAGYFVAKIRAVDADSGYNALLSYHISEPKGNN--LFRIGTSSGEIRTKRRMSDNDLKTHPLVVLVCDNGEPSLSATVSIDAVVVESGGDVKTPFRHAP---VKEESFSDLNLYLLIAIVSVSVIFLLSLIGLIAVKCHRT--DSSLGRYSAPMITTHPDGSWSYSKSTQQYDVCFSSDTLKSDVVVFPAPFPPADAELISINGGDTFTRTQTLPNKEKPKVPSSDWRYSASLRAGMQSSVRMEESSVMQGAQGVLVQNWPTVSSA-PDNEGGEVSPPVGAGVDSNSWHFRYGPGPGGPPHLKPGEVPPEAFIIPGSPAIISIRQ--GQDGDDKSDFITFGKKEEAKKLKKKKKKEKK-DKREKGKDDDD----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1N3Y6-1", "uniprot_id": "A0A8M1N3Y6_DANRE", "id": "A0A8M1N3Y6-1", "name": "", "aln": "----MAIVPLHNCLSVILFYVVFCFGSTAEGHIVYTVSEETNPGTTVGNLAKDLNLNLQDITNRGFQLVSGANKRYFELNSKTGFLHINDRIDRDELCGRSLKCSFPLEAIVNAPLNVYRFEVSIIDINDNSPTFRSPVKYFNISESAFPGERFPLPTAFDADVGSNSVKSYKLSANEHFSLDVQSGGEQSVSAELVLQKALDREKQPVIKLTLTAVDGGKPPRSGTINIIVNIEDVNDNIPVFSKPLFKTRVVENSPFGTSVIQVHASDPDEGPNSEIVYSLLSQD-NENNADAFAIDPETGVITVKGTVDYEKNAAVEIRVQAKDKGHKPRAAYCKVLVEITDINDNTPEISVTSLVNTVKEDAANGTVVSMITVLDNDAGKNGEIQLKIRDSLPFKVQNS-YKNYYTLIVNGHLDRETASEYNVTISAADEGTPPLSSTSVIAVHVSDVNDNAPRFPEPVINVYVKENSQIGAVLHTVSAVDPDVGDNARITYSLLE-SSKSGPVTSMININSDTGDLHSLQSFNYEEIKTFEFKVQATDSGVPPLSSNVTVNVFVLDENDNSPAILAPYSELGSVN-TENIPYSAEAGYFVAKIRAVDADSGYNALLSYHISEPKGNN--LFRIGTSSGEIRTKRRMSDNDLKTHPLVILVCDNGEPSLSATVSIDAVVVESGGDVKTPFRHAP---VKEESFSDLNLYLLIAIVSVSVIFLLSLISLIAVKCHRT--DSSLGRYSAPMITTHPDGSWSYSKSTQQYDVCFSSDTLKSDVVVFPAPFPPADAELISINGGDTFTRTQTLPNKEKPKVPSSDWRYSASLRAGMQSSVRMEESSVMQGAQGVLVQNWPTVSSA-PDNEGGEVSPPVGAGVDSNSWHFRYGPGPGGPPHLKPGEVPPEAFIIPGSPAIISIRQ--GQDGDDKSDFITFGKKEEAKKLKKKKKKEKK-DKREKGKDDDD----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1N3N1-1", "uniprot_id": "A0A8M1N3N1_DANRE", "id": "A0A8M1N3N1-1", "name": "", "aln": "MGVNMDISEDRWSFYWICIVVFLTNWNYADGQIVYSVSEEVNTGTTVGNLAKDLNLNVQDLERRGFQIVSGPNKQYFDLHARNGILFVRERIDREELCGRSSKCALELEAIVSAPMSIYRFEVNILDVNDNAPTFRTSKLFLNISEQTYPGQRFTLPSAFDLDAGVNSVKSYKLSANEHFSLDVQSAGDQSVSAELVLQKALDREKQPVIRLTLTAVDGGKPPMSGTTQIIVNVVDVNDNIPVFDKPLYKARIAENSAIGASVITVSAKDADEGLNGEVIYSFINHD-NENSINAFLINPNTGEITVKGPLDYEENAAIEIRVQAEDKGQNPRASHCKVLIEIIDLNDNTPEISIMSLVNEVKEDSAPGTMVGLITVKDGDAGKNGVVRLQIRDSAQFRLENT-YKNRFSLVVNGPLDREVASEYNVTISAADEGTPPLSSTSVIAVHVSDVNDNAPRFPEPVINVYVKENSQIGAVLHTVSAVDPDVGDNARITYSLLE-SSKSGPVTSMININSDTGDLHSLQSFNYEEIKTFEFKVQATDSGVPPLSSNVTVNVFVLDENDNSPAILAPYSELGSVN-TENIPYSAEAGYFVAKIRAVDADSGYNALLSYHISEPKGNN--LFRIGTSSGEIRTKRRMSDNDLKTHPLVILVCDNGEPSLSATVSIDAVVVESGGDVKTPFRHAP---VKEESFSDLNLYLLIAIVSVSVIFLLSLISLIAVKCHRT--DSSLGRYSAPMITTHPDGSWSYSKSTQQYDVCFSSDTLKSDVVVFPAPFPPADAELISINGGDTFTRTQTLPNKEKPKVPSSDWRYSASLRAGMQSSVRMEESSVMQGAQGVLVQNWPTVSSA-PDNEGGEVSPPVGAGVDSNSWHFRYGPGPGGPPHLKPGEVPPEAFIIPGSPAIISIRQ--GQDGDDKSDFITFGKKEEAKKLKKKKKKEKK-DKREKGKDDDD----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1N3N4-1", "uniprot_id": "A0A8M1N3N4_DANRE", "id": "A0A8M1N3N4-1", "name": "", "aln": "---MFSMHRRRSVVACFVLVVLVCFWDAASGQLSYSVSEEVSPGTTVGNLAKDLNLNVQELESRMFQIVTGAKKKYFEVNLKTGFLYVNERIDREELCAKAPKCTVSVEAVINNPLKLYQIEINIVDVNDNKPTFNSKTQYLDVAENTLPGVKFPLSYASDADVGKNTVSTYKLSQNEYFSLAVHKGEEQSVSAELVLQKALDREKQPLVQLTLTAADGGNPPKSGTSQIIIRVLDINDNAPVFSRPLYKASLVENVPIGSTVIIINATDKDEGTNSDIIYSLRETD-QDHILDIFQIDAITGAITVKGDVNFEKNNAFEIRAQASDKGQPPMSTHCKVLVEVLDINDNEPEITVTSLLSTVKEDASIGTAVALVSVIDRDGGRNGVVNCAVSNNVPFKLQTN-YKNYYSLVVDGPLDRERASEYNVTISAADEGSPPLSSTSVIAVHVSDVNDNAPRFPEPVINVYVKENSQIGAVLHTVSAVDPDVGDNARITYSLLE-SSKSGPVTSMININSDTGDLHSLQSFNYEEIKTFEFKVQATDSGVPPLSSNVTVNVFVLDENDNSPAILAPYSELGSVN-TENIPYSAEAGYFVAKIRAVDADSGYNALLSYHISEPKGNN--LFRIGTSSGEIRTKRRMSDNDLKTHPLVILVCDNGEPSLSATVSIDAVVVESGGDVKTPFRHAP---VKEESFSDLNLYLLIAIVSVSVIFLLSLISLIAVKCHRT--DSSLGRYSAPMITTHPDGSWSYSKSTQQYDVCFSSDTLKSDVVVFPAPFPPADAELISINGGDTFTRTQTLPNKEKPKVPSSDWRYSASLRAGMQSSVRMEESSVMQGAQGVLVQNWPTVSSA-PDNEGGEVSPPVGAGVDSNSWHFRYGPGPGGPPHLKPGEVPPEAFIIPGSPAIISIRQ--GQDGDDKSDFITFGKKEEAKKLKKKKKKEKK-DKREKGKDDDD----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1N3Y1-1", "uniprot_id": "A0A8M1N3Y1_DANRE", "id": "A0A8M1N3Y1-1", "name": "", "aln": "------MAHIIVMSGIVICLVLLLLMPSASAQVAYSISEEANTGTFVGNIAKDLNLNIQELESRGFHIPAVSGRKYFEVNLKTGVLFVSERIDREAFCPASPQCSVNLEAIVNNPLNLFRIEINIVDINDNSPSFRVRSMHINVSEYAFIGDRFQLPRASDPDVGANSVKSYKLSPNEHFSLDVQSGGEQSASAELVLQKALDREKQPAIHLTLTAVDGGKPPKSGTMQIAIHVQDVNDNAPVFGKALYKVRIVENAPLGTLVINLNATDLDEGLNSEIIYSLVQQDSDDKASSVFKIDSATGVVSMQGRVDFEERNAYEIHAQAKDKGASPRSAHCKILVEVLDVNDNEPEISLTSQVNTVREDAKRETTVALITISDKDSGKNGNVHGKVVGDVPFKLQSS-YKNYYSLVVDEPLDRERVDRYNVTIMASDEGAPPLSATRVFTVYVSDVNDNPPSFPNPVINVFVKENGPMDQIIYTLSAVDPDLNENSKITYGLLEPLHKSGSTYSAITINSDTGDLHSLQSFNYEEIKTFEFKVQATDSGVPPLSSNVTVNVFVLDENDNSPAILAPYSELGSVN-TENIPYSAEAGYFVAKIRAVDADSGYNALLSYHISEPKGNN--LFRIGTSSGEIRTKRRMSDNDLKTHPLVILVCDNGEPSLSATVSIDAVVVESGGDVKTPFRHAP---VKEESFSDLNLYLLIAIVSVSVIFLLSLISLIAVKCHRT--DSSLGRYSAPMITTHPDGSWSYSKSTQQYDVCFSSDTLKSDVVVFPAPFPPADAELISINGGDTFTRTQTLPNKEKPKVPSSDWRYSASLRAGMQSSVRMEESSVMQGAQGVLVQNWPTVSSA-PDNEGGEVSPPVGAGVDSNSWHFRYGPGPGGPPHLKPGEVPPEAFIIPGSPAIISIRQ--GQDGDDKSDFITFGKKEEAKKLKKKKKKEKK-DKREKGKDDDD----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1N3X5-1", "uniprot_id": "A0A8M1N3X5_DANRE", "id": "A0A8M1N3X5-1", "name": "", "aln": "---MANENTRTWMSRIFYLMCLLFNSGGKAAQINYSLQEESKIGVNVGNIAKDLGIDPTSLENRNFRIVVGTKQELFRVNHEDGALFVSQRIDREELCAKINPCLINLKAVIENPLEMHQISVDIIDVNDNPPSFLDENYKLEILESAMTGARFQVETAHDPDIGSNDLQSYKLSQNHYFRLETEDMGDEGKIPVLILQKPLDREKSARHNLILTATDGGKPHKSAAANITIVVSDVNDNTPVCDKQKYTVTVKEDAPEGTFLLRVNASDSDEGVNGEIEYSLRNKF-RKGASDVFDLDNITGELKIKGGLNFEERQVYELKILAADKGAVSLSTQCNVLVNVEDVNDNRPEIDVTSLSSHIPEDAAPGTVVALIGVTDLDSGMNGKIICSLPKNIPFDLKPSPDGNFYSLVTKENIDKEAKSSYDITITAKDLGSPSLSSTRSIHVEVTDVNDNSPKFAQSPYTFYVTENNKPGIAVFSLSASDLDEGENARVSYTIDR-INSDQSMTSFLSINEANGTVYSLKSFDFESLKTFHFFVVAKDSGSPSLSSNVTVNVFILDQNDNVPVILYPVSANGSAEGVEEIPRNVNAGHLVTKVRAYDADIGYNGWLLFSLQEVSEHS--LFALDRYTGQIRTLRSFTETDEAQHKLVILVKDNGNVSLSATATVIVKVVEPKEAFAASDVKNA---VKDKEENNVTFYLIITLGSVSVLFVISIIVLIVMQCSKS--TDYSSKY---LQDTNYDGTLCHSIQYRSGDKRYMLVGPRMSIGSTIAPGS---------NRNTLVIPDRRRRDSGEPKVPSSDWRYSASLRAGMQSSVRMEESSVMQGAQGVLVQNWPTVSSA-PDNEGGEVSPPVGAGVDSNSWHFRYGPGPGGPPHLKPGEVPPEAFIIPGSPAIISIRQ--GQDGDDKSDFITFGKKEEAKKLKKKKKKEKK-DKREKGKDDDD----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q767I8-1", "uniprot_id": "PCDA4_RAT", "id": "Q767I8-1", "name": "Protocadherin alpha-4", "aln": "--MEFSWGSGQESQRLLLSFLFLAIWEPGNSQLHYSIPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKDRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVEVRDINDNPPTFPTTQKNLFIAESRPLDTWFPLEGASDSDIGINAVLTYRLSPNDYFSLEKPTNSERVKGLGLILRKSLDREETPELFLVLTVTDGGKPELTGSVQLLITVLDANDNSPVFDRSLYTVKLPENVPNGTLVVKVNASDLDEGANGEVMYSFSTDI-SPNVKNKFHIDPVTGEIAVKGYIDFEECTSYEILIEGIDKGQLPLSGHCKVIVQVEDINDNAPELEFKSLSLPIRENAPVGTVIALISVFDPDTGVNGQVTCSLTPQVPFKLVST-FKNYYSLVLDSALDRETTADYKVVVIARDGGLPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGAHIFTVSAVDADSQENALVSYSLVERRVGERLLSSYVSVHAESGKVFALQPLDHEELELLQFQVSARDAGVPALGSNVTLQVFVLDENDNAPTLLEPEAGISGGIVSRLVSRSVGAGHVVAKVRAVDADSGYNAWLSYELQSSEGNSRSLFRVGLYTGEISTTRSLDEADSPRQRLLVLVKDHGDPAMMVTATVLVSLVENGPLPKAPSRVSTRVTNAEASLVDVNVYLIIAICAVSSLLVLTLLLYSALRCSTVPSESVCGPPKPVMVCSSAVGSWSYSQQRRQ-RVCSGEYPPKTDLMAFSPSLSD------SRDREDQLQSTED--SSGKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPG--NPKQPGPGELP-DKFIIPGSPAIISIRQESANNQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88689-1", "uniprot_id": "PCDA4_MOUSE", "id": "O88689-1", "name": "Protocadherin alpha-4", "aln": "--MEFSWGSGQESQRLLLSFLLLAIWEAGNSQIHYSIPEEAKHGTFVGRIAQDLGLELTELVPRLFRVASKDRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVEVRDINDNPPRFPTTQKNLFIAESRPLDTWFPLEGASDADIGINAVLTYRLSPNDYFSLEKPSNDERVKGLGLVLRKSLDREETPEIILVLTVTDGGKPELTGSVQLLITVLDANDNAPVFDRSLYTVKLPENVPNGTLVVKVNASDLDEGVNGDIMYSFSTDI-SPNVKYKFHIDPVSGEIIVKGYIDFEECKSYEILIEGIDKGQLPLSGHCKVIVQVEDINDNVPELEFKSLSLPIRENSPVGTVIALISVSDRDTGVNGQVTCSLTSHVPFKLVST-FKNYYSLVLDSALDRETTADYKVVVTARDGGSPSLWATASVSVEVADVNDNAPVFAQPEYTVFVKENNPPGAHIFTVSAMDADAQENALVSYSLVERRVGERLLSSYVSVHAESGKVFALQPLDHEELELLRFQVSARDAGVPALGSNVTLQVFVLDENDNAPTLLEPEAGVSGGIVSRLVSRSVGAGHVVAKVRAVDADSGYNAWLSYELQSSEGNSRSLFRVGLYTGEISTTRILDEADSPRQRLLVLVKDHGDPAMIVTATVLVSLVENGPVPKAPSRVSTSVTHSEASLVDVNVYLIIAICAVSSLLVLTLLLYTALRCSTVPSESVCGPPKPVMVCSSAVGSWSYSQQRRQ-RVCSGEYPPKTDLMAFSPSLSD------SRDREDQLQSAED--SSGKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPG--NPKQSGPGELP-DKFIIPGSPAIISIRQEPANNQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UN74-1", "uniprot_id": "PCDA4_HUMAN", "id": "Q9UN74-1", "name": "Protocadherin alpha-4", "aln": "--MEFSWGSGQESRRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSLEKPPDDELVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAFDRTIYKVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDI-SPNVKSKFHIDPITGQIIVKGYIDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIREDAPLGTVIALISVSDKDMGVNGLVTCSLTSHVPFKLVST-FKNYYSLVLDSALDRESVSAYELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDAGVPPLGSNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDADSGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALTATATVLVSLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALPTEGACAPGKPTLVCSSAVGSWSYSQQRRP-RVCSGEGPPKTDLMAFSPSLPD------SRDREDQLQTTEE--SFAKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPG--NPKQSGPGELP-DKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .. .:: *:: ** . *. **.:*:*:.:: .: * *:: : .: . * *.: .****: :* * . ::.::. *:.:.:..:.: *:*** * * : : * . * : * * * * * : :*:** *.:* * : *:*:*.****: . * **..***:* :.: :: : : * *** *. .: :.. : *: . *: :: : *.* *** *.:: *:: * :: :* : ::* :::*. *: . *** . : *.::::: * *** *:: . * : *:: * :.:: : * * * ** : : * : . * ::*. . :*:* *.:.: * * * *.* :* . * *:*****.* *.:. ..:*.**. . :.::** * * :*: ::* : . . * :.:: .* :.:*:.::.*.:: :.* * * *:* *.*.****::**:**:*** *.:* * : . . :. .. .*:.*:*:** *** ***. * : :. * :. :*:* * * : : * : *::** *:*: :: .*.:: . :** :. : ::..**:*:: :** ::::::: .::* . . : : *: .:* . : : .: .. . : . . . :*: *..************:***::**:.:::.. * *:******* *: *.***********:**** *:**** .* : ***:* : ************** :. *************:** ***** :*. :*:***:. * ", "identical_positions": 272, "similar_positions": 296, "identity": "28.25%" }, { "cls_id": "homologset.agr.MGI:1298407", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P41732-1", "uniprot_id": "TSN7_HUMAN", "id": "P41732-1", "name": "Tetraspanin-7", "aln": "MASRRMETKPVITCLKTLLIIYSFVFWITGVILLAVGVWGKLTLGTYISLIAENSTNAPYVLIGTGTTIVVFGLFGCFATCRGSPWMLKLYAMFLSLVFLAELVAGISGFVFRHEIKDTFLRTYTDAMQTYNGNDERSRAVDHVQRSLSCCGVQNYTNWSTSPYFLEHGIPPSCCMNETDCNPQDLHNLTVAATKVNQKGCYDLVTSFMETNMGIIAGVAFGIAFSQLIGMLLACCLSRFITANQYEMV------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q62283-1", "uniprot_id": "TSN7_MOUSE", "id": "Q62283-1", "name": "Tetraspanin-7", "aln": "MASRRMETKPVITCLKTLLIIYSFVFWITGVILLAVGVWGKLTLGTYISLIAENSTNAPYVLIGTGTTIVVFGLFGCFATCRGSPWMLKLYAMFLSLVFLAELVAGISGFVFRHEIKDTFLRTYTDAMQNYNGNDERSRAVDHVQRSLSCCGVQNYTNWSSSPYFLDHGIPPSCCMNETDCNPLDLHNLTVAATKVNQKGCYDLVTSFMETNMGIIAGVAFGIAFSQLIGMLLACCLSRFITANQYEMV------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B0BNE7-1", "uniprot_id": "B0BNE7_RAT", "id": "B0BNE7-1", "name": "Tetraspanin", "aln": "MASRRMETKPVITCLKTLLIIYSFVFWITGAILLAVGVWGKLTLGTYISLIAENSTNAPYVLIGTGTTIVVFGLFGCFATCRGSPWMLKLYAMFLSLVFLAELVAGISGFVFRHEIKDTFLRTYTDAMQNYNGKDERSRAVDHVQRSLSCCGVQNYTNWSSSPYFLEHGIPPSCCMNETDCNPLDLHNLTVAATKVNQKGCYDLVTSFMETNMGIIAGVAFGIAFSQLIGMLLACCLSRFITANQYEMV------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B0VEQ2-1", "uniprot_id": "B0VEQ2_DANRE", "id": "B0VEQ2-1", "name": "Tetraspanin", "aln": "MASRRMETKPVITCLKTLLIVYSFVFWITGAILLAVGLWGKFILGPYISLIAENSTNAPYVLIGTGTTIIVFGLFGCFATCRGSPWMLKLYAMFLSLVFLAELVAGISGFVFRHEIKGTFLRTYNEAVQNYNAQDERSIAVDNVQRSLRCCGVLNYTSWFSSVYFPVNGIPPSCCANISDCNASDLRNATIAPTKVYQQGCYELVTTFIETNMGIIAGVTFGIAFSQLIGMLLACCLSRFITANQYEMV------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M0RAB0-1", "uniprot_id": "M0RAB0_RAT", "id": "M0RAB0-1", "name": "Tetraspanin", "aln": "-----METKFVASCLKIFLLIYSFAFWSTGVILLAFGVWGKLTLGTYLSLLAKNIADIPFVLIGIGTMIIIFGLFGCFASCRGSPWMLKLYSLFLSLVFLIELVASISGLLLHREIKDRFLKIYTNAIQNYNGNDKKSQAVDQVQYGLMCCGVKNYKDWNDNPYFLNHGIPQSCCKDETDCNPPDLHNLTTAATKVNKRGCYDLMIGFFEANMAVIIGMLFTTTFSQLIGIRLSCCLSRIIMTQRYKRCVKSSKRNSLLQE", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **** * :*** :*::***.** **.****.*:***: **.*:**:*:* :: *:**** ** *::********:***********::******* ****.***:::::***. **: *.:*:*.**.:*::* ***:** .* **** **..* . ** :*** *** : :***. **:* * *.*** ::***:*: *:*:**.:* *: * :******: *:*****:* :::*: ", "identical_positions": 141, "similar_positions": 65, "identity": "54.02%" }, { "cls_id": "homologset.agr.MGI:1298408", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8N7UY30-1", "uniprot_id": "A0A8N7UY30_DANRE", "id": "A0A8N7UY30-1", "name": "", "aln": "----MALTRTHVLRSWIFFSVFLCCWIFTNGQIVYSISEEANPGTAVGNLAKDFNLNVQDIERRGFQIVSESNKRYFDFNFKTGVLHVKERIDREELCEQKIKCSLPLEAIVNSPLNVFRFEINVLDINDNPPKFRTPKTTINISESALPGEQFALPSAFDADVGINSVKSYKLSPNEHFSLDVQSGGEQSVSAELVLQKALDREKQPLIRLTLTAVDGGKPLRSGTMQITVHVEDVNDNIPVFSKSLYKARVNENAPPGTSIITVQASDPDEGVNGQIVYALVNHD-NDRNVESFAINPETGEITVKGDVDYERKNAVELRVQAKDKGHKPRAALCKVLLEIIDVNDNVPEISVTSLVNTVKEDALIDTVVGMITVTDNDAGKNGQVILNIQGSSPFKVQNS-YKNYYTLFVNGPLDRERASEYNVTISAADEGTPPLSSTSVIAVHVSDVNDNAPRFPEPVINVYVKENSQIGAVLHTVSAVDPDVGDNARITYSLLE-SSKSGPVTSMININSDTGDLHSLQSFNYEEIKTFEFKVQATDSGVPPLSSNVTVNVFVLDENDNSPAILAPYSELGSVN-TENIPYSAEAGYFVAKIRAVDADSGYNALLSYHISEPKG--NNLFRIGTSSGEIRTKRRMSDNDLKTHPLVVLVCDNGEPSLSATVSIDAVVVESGGDVKTPFRHA--PVKEESFSDLNLYLLIAIVSVSVIFLLSLIGLIAVKCHR--TDSSLGRYSAPMITTHPDGSWSYSKSTQQYDVCFSSDTLKSDVVVFPAPFPPADAELISINGGDTFTRTQTLPNKEKPKVPSSDWRYSASLRAGMQSSVRMEESSVMQGAQGVLVQNWPTVSSA-PDNEGGEVSPPVGAGVDSNSWHFRYGPGPGGPPHLKPGEVPPEAFIIPGSPAIISIRQ--GQDGDDKSDFITFGKKEEAKKLKKKKKKEKK-DKREKGKDDDD----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1N3Y6-1", "uniprot_id": "A0A8M1N3Y6_DANRE", "id": "A0A8M1N3Y6-1", "name": "", "aln": "----MAIVPLHNCLSVILFYVVFCFGSTAEGHIVYTVSEETNPGTTVGNLAKDLNLNLQDITNRGFQLVSGANKRYFELNSKTGFLHINDRIDRDELCGRSLKCSFPLEAIVNAPLNVYRFEVSIIDINDNSPTFRSPVKYFNISESAFPGERFPLPTAFDADVGSNSVKSYKLSANEHFSLDVQSGGEQSVSAELVLQKALDREKQPVIKLTLTAVDGGKPPRSGTINIIVNIEDVNDNIPVFSKPLFKTRVVENSPFGTSVIQVHASDPDEGPNSEIVYSLLSQD-NENNADAFAIDPETGVITVKGTVDYEKNAAVEIRVQAKDKGHKPRAAYCKVLVEITDINDNTPEISVTSLVNTVKEDAANGTVVSMITVLDNDAGKNGEIQLKIRDSLPFKVQNS-YKNYYTLIVNGHLDRETASEYNVTISAADEGTPPLSSTSVIAVHVSDVNDNAPRFPEPVINVYVKENSQIGAVLHTVSAVDPDVGDNARITYSLLE-SSKSGPVTSMININSDTGDLHSLQSFNYEEIKTFEFKVQATDSGVPPLSSNVTVNVFVLDENDNSPAILAPYSELGSVN-TENIPYSAEAGYFVAKIRAVDADSGYNALLSYHISEPKG--NNLFRIGTSSGEIRTKRRMSDNDLKTHPLVILVCDNGEPSLSATVSIDAVVVESGGDVKTPFRHA--PVKEESFSDLNLYLLIAIVSVSVIFLLSLISLIAVKCHR--TDSSLGRYSAPMITTHPDGSWSYSKSTQQYDVCFSSDTLKSDVVVFPAPFPPADAELISINGGDTFTRTQTLPNKEKPKVPSSDWRYSASLRAGMQSSVRMEESSVMQGAQGVLVQNWPTVSSA-PDNEGGEVSPPVGAGVDSNSWHFRYGPGPGGPPHLKPGEVPPEAFIIPGSPAIISIRQ--GQDGDDKSDFITFGKKEEAKKLKKKKKKEKK-DKREKGKDDDD----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1N3N1-1", "uniprot_id": "A0A8M1N3N1_DANRE", "id": "A0A8M1N3N1-1", "name": "", "aln": "MGVNMDISEDRWSFYWICIVVFLTNWNYADGQIVYSVSEEVNTGTTVGNLAKDLNLNVQDLERRGFQIVSGPNKQYFDLHARNGILFVRERIDREELCGRSSKCALELEAIVSAPMSIYRFEVNILDVNDNAPTFRTSKLFLNISEQTYPGQRFTLPSAFDLDAGVNSVKSYKLSANEHFSLDVQSAGDQSVSAELVLQKALDREKQPVIRLTLTAVDGGKPPMSGTTQIIVNVVDVNDNIPVFDKPLYKARIAENSAIGASVITVSAKDADEGLNGEVIYSFINHD-NENSINAFLINPNTGEITVKGPLDYEENAAIEIRVQAEDKGQNPRASHCKVLIEIIDLNDNTPEISIMSLVNEVKEDSAPGTMVGLITVKDGDAGKNGVVRLQIRDSAQFRLENT-YKNRFSLVVNGPLDREVASEYNVTISAADEGTPPLSSTSVIAVHVSDVNDNAPRFPEPVINVYVKENSQIGAVLHTVSAVDPDVGDNARITYSLLE-SSKSGPVTSMININSDTGDLHSLQSFNYEEIKTFEFKVQATDSGVPPLSSNVTVNVFVLDENDNSPAILAPYSELGSVN-TENIPYSAEAGYFVAKIRAVDADSGYNALLSYHISEPKG--NNLFRIGTSSGEIRTKRRMSDNDLKTHPLVILVCDNGEPSLSATVSIDAVVVESGGDVKTPFRHA--PVKEESFSDLNLYLLIAIVSVSVIFLLSLISLIAVKCHR--TDSSLGRYSAPMITTHPDGSWSYSKSTQQYDVCFSSDTLKSDVVVFPAPFPPADAELISINGGDTFTRTQTLPNKEKPKVPSSDWRYSASLRAGMQSSVRMEESSVMQGAQGVLVQNWPTVSSA-PDNEGGEVSPPVGAGVDSNSWHFRYGPGPGGPPHLKPGEVPPEAFIIPGSPAIISIRQ--GQDGDDKSDFITFGKKEEAKKLKKKKKKEKK-DKREKGKDDDD----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1N3N4-1", "uniprot_id": "A0A8M1N3N4_DANRE", "id": "A0A8M1N3N4-1", "name": "", "aln": "---MFSMHRRRSVVACFVLVVLVCFWDAASGQLSYSVSEEVSPGTTVGNLAKDLNLNVQELESRMFQIVTGAKKKYFEVNLKTGFLYVNERIDREELCAKAPKCTVSVEAVINNPLKLYQIEINIVDVNDNKPTFNSKTQYLDVAENTLPGVKFPLSYASDADVGKNTVSTYKLSQNEYFSLAVHKGEEQSVSAELVLQKALDREKQPLVQLTLTAADGGNPPKSGTSQIIIRVLDINDNAPVFSRPLYKASLVENVPIGSTVIIINATDKDEGTNSDIIYSLRETD-QDHILDIFQIDAITGAITVKGDVNFEKNNAFEIRAQASDKGQPPMSTHCKVLVEVLDINDNEPEITVTSLLSTVKEDASIGTAVALVSVIDRDGGRNGVVNCAVSNNVPFKLQTN-YKNYYSLVVDGPLDRERASEYNVTISAADEGSPPLSSTSVIAVHVSDVNDNAPRFPEPVINVYVKENSQIGAVLHTVSAVDPDVGDNARITYSLLE-SSKSGPVTSMININSDTGDLHSLQSFNYEEIKTFEFKVQATDSGVPPLSSNVTVNVFVLDENDNSPAILAPYSELGSVN-TENIPYSAEAGYFVAKIRAVDADSGYNALLSYHISEPKG--NNLFRIGTSSGEIRTKRRMSDNDLKTHPLVILVCDNGEPSLSATVSIDAVVVESGGDVKTPFRHA--PVKEESFSDLNLYLLIAIVSVSVIFLLSLISLIAVKCHR--TDSSLGRYSAPMITTHPDGSWSYSKSTQQYDVCFSSDTLKSDVVVFPAPFPPADAELISINGGDTFTRTQTLPNKEKPKVPSSDWRYSASLRAGMQSSVRMEESSVMQGAQGVLVQNWPTVSSA-PDNEGGEVSPPVGAGVDSNSWHFRYGPGPGGPPHLKPGEVPPEAFIIPGSPAIISIRQ--GQDGDDKSDFITFGKKEEAKKLKKKKKKEKK-DKREKGKDDDD----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1N3Y1-1", "uniprot_id": "A0A8M1N3Y1_DANRE", "id": "A0A8M1N3Y1-1", "name": "", "aln": "------MAHIIVMSGIVICLVLLLLMPSASAQVAYSISEEANTGTFVGNIAKDLNLNIQELESRGFHIPAVSGRKYFEVNLKTGVLFVSERIDREAFCPASPQCSVNLEAIVNNPLNLFRIEINIVDINDNSPSFRVRSMHINVSEYAFIGDRFQLPRASDPDVGANSVKSYKLSPNEHFSLDVQSGGEQSASAELVLQKALDREKQPAIHLTLTAVDGGKPPKSGTMQIAIHVQDVNDNAPVFGKALYKVRIVENAPLGTLVINLNATDLDEGLNSEIIYSLVQQDSDDKASSVFKIDSATGVVSMQGRVDFEERNAYEIHAQAKDKGASPRSAHCKILVEVLDVNDNEPEISLTSQVNTVREDAKRETTVALITISDKDSGKNGNVHGKVVGDVPFKLQSS-YKNYYSLVVDEPLDRERVDRYNVTIMASDEGAPPLSATRVFTVYVSDVNDNPPSFPNPVINVFVKENGPMDQIIYTLSAVDPDLNENSKITYGLLEPLHKSGSTYSAITINSDTGDLHSLQSFNYEEIKTFEFKVQATDSGVPPLSSNVTVNVFVLDENDNSPAILAPYSELGSVN-TENIPYSAEAGYFVAKIRAVDADSGYNALLSYHISEPKG--NNLFRIGTSSGEIRTKRRMSDNDLKTHPLVILVCDNGEPSLSATVSIDAVVVESGGDVKTPFRHA--PVKEESFSDLNLYLLIAIVSVSVIFLLSLISLIAVKCHR--TDSSLGRYSAPMITTHPDGSWSYSKSTQQYDVCFSSDTLKSDVVVFPAPFPPADAELISINGGDTFTRTQTLPNKEKPKVPSSDWRYSASLRAGMQSSVRMEESSVMQGAQGVLVQNWPTVSSA-PDNEGGEVSPPVGAGVDSNSWHFRYGPGPGGPPHLKPGEVPPEAFIIPGSPAIISIRQ--GQDGDDKSDFITFGKKEEAKKLKKKKKKEKK-DKREKGKDDDD----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1N3X5-1", "uniprot_id": "A0A8M1N3X5_DANRE", "id": "A0A8M1N3X5-1", "name": "", "aln": "---MANENTRTWMSRIFYLMCLLFNSGGKAAQINYSLQEESKIGVNVGNIAKDLGIDPTSLENRNFRIVVGTKQELFRVNHEDGALFVSQRIDREELCAKINPCLINLKAVIENPLEMHQISVDIIDVNDNPPSFLDENYKLEILESAMTGARFQVETAHDPDIGSNDLQSYKLSQNHYFRLETEDMGDEGKIPVLILQKPLDREKSARHNLILTATDGGKPHKSAAANITIVVSDVNDNTPVCDKQKYTVTVKEDAPEGTFLLRVNASDSDEGVNGEIEYSLRNKF-RKGASDVFDLDNITGELKIKGGLNFEERQVYELKILAADKGAVSLSTQCNVLVNVEDVNDNRPEIDVTSLSSHIPEDAAPGTVVALIGVTDLDSGMNGKIICSLPKNIPFDLKPSPDGNFYSLVTKENIDKEAKSSYDITITAKDLGSPSLSSTRSIHVEVTDVNDNSPKFAQSPYTFYVTENNKPGIAVFSLSASDLDEGENARVSYTIDR-INSDQSMTSFLSINEANGTVYSLKSFDFESLKTFHFFVVAKDSGSPSLSSNVTVNVFILDQNDNVPVILYPVSANGSAEGVEEIPRNVNAGHLVTKVRAYDADIGYNGWLLFSLQEVSE--HSLFALDRYTGQIRTLRSFTETDEAQHKLVILVKDNGNVSLSATATVIVKVVEPKEAFAASDVKN--AVKDKEENNVTFYLIITLGSVSVLFVISIIVLIVMQCSK--STDYSSKY---LQDTNYDGTLCHSIQYRSGDKRYMLVGPRMSIGSTIAPGS---------NRNTLVIPDRRRRDSGEPKVPSSDWRYSASLRAGMQSSVRMEESSVMQGAQGVLVQNWPTVSSA-PDNEGGEVSPPVGAGVDSNSWHFRYGPGPGGPPHLKPGEVPPEAFIIPGSPAIISIRQ--GQDGDDKSDFITFGKKEEAKKLKKKKKKEKK-DKREKGKDDDD----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q91Y20-1", "uniprot_id": "PCDAA_MOUSE", "id": "Q91Y20-1", "name": "Protocadherin alpha-10", "aln": "-MSCVAMKYCHESWCLLLSLLLFAIWEPGSGQLRYSVPEEAKHGTFVGRIAQDLGLELTELVPRLFRVASKDRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVEVRDINDNPPVFPTTEKNLFVSESRALDPHFSLEGASDADIGTNALLTYRLSPSEYFSLEVPTTDELVKPLQLVLKKPLDRERASELHLVVKATDGGKPELTGTLELHITVLDANDNAPAFDRAIYRVKLVENARNGTVVIRLNASDLDEGSNGQILYSFAADV-SPKTEATFHIDSVSGEIKVNGKIDFEETNLWKIQAEAVDKGSPPMFGHCTILIEVLDINDNAPKIIVTSLSLPVQEDAPVGTVIALISVMDPDSTVNGQVTCSLSPHVPFKLVST-FKNYYSLVLDSALDRETTADYKVVVTARDGGSPALWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGVHVFTVLAMDADAQENALVSYSLVERRVGERLLSSYVSVHAESGKVFALQPLDHEELELLQFQVTAKDAGVPALGSNVTLQVFVLDENDNAPTLLPHGAVGAGGAVSELVPRSVGSGHVVAKVRAVDADSGYNAWLSYELQFRAGSVRSPFRVGLYTGEISITRALDEADAPRQRLLVLVKDHGEPALTATATVLVSLVESNQAPKASSRVLGPAASESSVVDVNVYLIIAICAVSSLLVLTLVLYTALRCSALPTEVTCGPGKPMLVCSSAVGSWSYSQQRRQ-RVCSGEGPPKTDLMAFSPSVPPG------LGSGDSGVQQEIFEN---PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPG--NPKQSGPGELP-DKFIIPGSPAIISIRQEPANNQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .. .:: *:: ** . *. **.:*:*:.:: .: * *:: : .: . * *.: .****: :* * . ::.::. *:.:.:..:.: *:*** * * : : * . :* : * * * * * : :*:** ..:* * . : *:*:*.****: . .* :.*.***:* :.: :: : : * *** *. .: : . : *: *: :: : *.* *** *.:: *:: * :: :* :.::* :::*. ::: * *** . *.:*::: *:*** *:* : * : **: * :.:: : * *. ** : : * : . * ::*. . :*:* *.:.: * * *:*.* :* . * *:*****.* *.:. ..:*.**. . :.:: * * * :*: ::* : . . * :.:: .* :.:*:.::.*.:: :.* * *.*:* *.*.****::**:**:*** *.:* : .. * :* .. :*:.*:*:** *** ***. * : :. .. * :. :*:* * : : * : *::** *:*: :*:**.:: . :**. :. ...:.. ::..**:*:: :** ::::::: .::* : . : : *: .:* . :. : .: .. . . . . : *: *..************:***::**:.:::.. * *:******* *: *.***********:**** *:**** .* : ***:* : ************** .:: *************:** ***** :*. :*:***:. * ", "identical_positions": 273, "similar_positions": 308, "identity": "28.38%" }, { "cls_id": "homologset.agr.MGI:1306775", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A1U8-1", "uniprot_id": "A0A8I6A1U8_RAT", "id": "A0A8I6A1U8-1", "name": "Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial", "aln": "MAASMFFGRQLAAAALRSHRSQTTVRATAQALGSSGLFNKHGFQMQQQQQQQRSLSLHEYLSMELLQEAGVSVPKGFVAKSSDEAYAIAKKLGSKDVVIKAQVLAGGRGKGTFTSGLKGGVKIVFSPEEAKAVSSQMIGQKLITKQTGAKGRICNQVLVCERKYPRREYYFAITMERSFQGPVLIGSSQGGVNIEDVAAENPEAIVKEPVDIIEGVKKEQAVTLAKKMGFPSNIVDSAAENMIKLYNLFLKYDATMVEINPMVE---DADG--------------KAYRQKKIFALQDWSQEDERDKDAADADINYIGLDGNIGCLVNGAGLAMATMDIIKLHGGTPANFLDVGGGATVHQVTEAFKLITSDKRVQAILVNIFGGIMRCDIIAQGIVMAVKDLEIRIPVVVRLQGTRVDDAKALIADSGLKILACDDLDEAAKMVVKLSEIVTLAKEAHVDVKFQLPI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z2I9-1", "uniprot_id": "SUCB1_MOUSE", "id": "Q9Z2I9-1", "name": "Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial", "aln": "MAASMFYGRQLAAAALRSHRPQTTLRAAAQVLGNSGLFNKHGLQVQQQQQ--RTLSLHEYLSMELLQEAGVSVPKGFVAKSSDEAYAIAKKLGSKDVVIKAQVLAGGRGKGTFTSGLKGGVKIVFSPEEAKAVSSQMIGQKLITKQTGEKGRICNQVLVCERKYPRREYYFAITMERSFQGPVLIGSAQGGVNIEDVAAENPEAIVKEPIDIVEGIKKEQAVTLAQKMGFPSNIVDSAAENMIKLYNLFLKYDATMVEINPMVE---DSDGKVLCMDAKINFDSNSAYRQKKIFDLQDWSQEDERDKEAANADINYIGLDGSIGCLVNGAGLAMATMDIIKLHGGTPANFLDVGGGATVQQVTEAFKLITSDKKVQAILVNIFGGIMRCDVIAQGIVMAVKDLEIRIPVVVRLQGTRVDDAKALIADSGLKILACDDLDEAAKMVVKLSEIVTLAKEAHVDVKFQLPI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P2R7-1", "uniprot_id": "SUCB1_HUMAN", "id": "Q9P2R7-1", "name": "Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial", "aln": "MAASMFYGRLVAVATLRNHRPRTAQRAAAQVLGSSGLFNNHGLQVQQQQQ--RNLSLHEYMSMELLQEAGVSVPKGYVAKSPDEAYAIAKKLGSKDVVIKAQVLAGGRGKGTFESGLKGGVKIVFSPEEAKAVSSQMIGKKLFTKQTGEKGRICNQVLVCERKYPRREYYFAITMERSFQGPVLIGSSHGGVNIEDVAAESPEAIIKEPIDIEEGIKKEQALQLAQKMGFPPNIVESAAENMVKLYSLFLKYDATMIEINPMVE---DSDGAVLCMDAKINFDSNSAYRQKKIFDLQDWTQEDERDKDAAKANLNYIGLDGNIGCLVNGAGLAMATMDIIKLHGGTPANFLDVGGGATVHQVTEAFKLITSDKKVLAILVNIFGGIMRCDVIAQGIVMAVKDLEIKIPVVVRLQGTRVDDAKALIADSGLKILACDDLDEAARMVVKLSEIVTLAKQAHVDVKFQLPI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P53312-1", "uniprot_id": "SUCB_YEAST", "id": "P53312-1", "name": "Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial", "aln": "MYS----------------------RKSLSLISKCGQLSRLNAQAALQAR--RHLSIHEYRSAQLLREYGIGTPEGFPAFTPEEAFEAAKKLNTNKLVIKAQALTGGRGKGHFDTGYKSGVHMIESPQQAEDVAKEMLNHNLITKQTGIAGKPVSAVYIVKRVDTKHEAYLSILMDRQTKKPMIIASSQGGMNIEEVAERTPDAIKKFSIETSKGLSPQMAKDVAKSLGFSPDAQDEAAKAVSNLYKIFMERDATQVEINPLSEIEHDPTHKIMCTDAKFGFDDNASFRQEKIYSWRDLSQEDPDEVKAKKYDLNFVKLKGNIGCLVNGAGLAMATMDVIKLNGGDPANFLDCGGGATPETIKQGFELILSNKNVDAIFVNIFGGIVRCDYVALGLVEAARELEVRVPIVARLQGTKVEEGRDIINKSGVKIYSFDELDPAAKKVVELTQN-----------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : * : . :...* :.. . * * : * **:*** * :**:* *:..*:*: * :.:**: ****.::.:*****.*:****** * :* *.**::: **::*: *:.:*:.::*:***** *: . * : :* .::* *::* *:*. : *::*.*::**:***:** ..*:** * .:: :*:. : * :*:.:**..: :.**: : :**.:*:: *** :****: * *. ::**:**: :* :*** : .* . ::*:: *.*.****************:***:** ****** ***** . :.:.*:** *:*.* **:*******:*** :* *:* *.::**:::*:*.*****:*::.: :* .**:** : *:** **: **:*:: ", "identical_positions": 183, "similar_positions": 146, "identity": "39.1%" }, { "cls_id": "homologset.agr.MGI:1306776", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P34926-1", "uniprot_id": "MAP1A_RAT", "id": "P34926-1", "name": "Microtubule-associated protein 1A", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDGVAEFSEYVSETVDVPSPFDLLEPPTSGGFLKLSKPCCYIFPGGRGDSALFAVNGFNILVDGGSDRKSCFWKLVRHLDRIDSVLLTHIGADNLPGINGLLQRKVAELEEEQSQGSSSYSDWVKNLISPELGVVFFNVPDKLRLPDASRKAKRS------IEEACLTLQHLNRLGIQAEPLYRVVSNTIEPLTLFHKMGVGRLDMYVLNPVKDSKEMQFLMQKWAGNSKAKTGIVLANGKEAEISVPYLTSITALVVWLPANPTEKIVRVLFPGNAPQNKILEGLEKLRHLDFLRYPVATQKDLAAGAVPANLKPSKIKHRADSK-------------------------------------------ESLKAAPKTAVSKLAKREEVLEEGAKEARSELAKELAKTEKKAKEPSEKPPEKPSKSERVRG----------------------------------------------------ESSEALKAEKRRLIKDKAGKKHLKEKISKLEEKKDKEKKEIKK-------------------------------------ERKELKKEEGRKEEKKDAKKDEKRKDTKPEVKKLSKPDLKPFTPEVRKTLYKAKAPGRVK------------------------VDKGRAARGEKELSSEPRTPPAQKGAAPPAAVSGHRELALSSP------------------------------------------------------------------------------------------------------------EDLTQDFEELKREERGLLAEQRDTGLGEKPLPADATEQGHPSAAIQVTQPSGPVLEGE-HVEREKEVVPDSPGDKGST-------------------------------------------------------------------------------------------------------------NRGPDSGAEVEKEKETWEE-------------------RKQREAELGPEN-TAAREESEAEVKEDVIEKAELEEMEETHPSDEEGE-ETKAESFYQKHTQEALKASPKS--------------------------------------REALGGRDLGFQGKAPEKETASFLSSLATPAGATEHVSYIQDETIPGYSETEQTISDEEIHDE--------------------------------PDERPAPPRFPTSTYDLSGPEGPG------------------------------PFEASQAADSAVPASSSKTYG------APETELTYPPNMVAAPLAEEEHVSS-----------------------------ATSITECDKLSSFATSVAEDQSVASLTAPQTEETGKSSLLLDTVTSIPSS-------------------------------------------------------------------------------------------------------------------RTEATQGLDYVPSAGTISPTSSLEEDKGFKSPPCEDFS----------------------------------------------------------------------------VTGESEKKGETVGRGLSGEKAVGKEEK-----------------------------YVVTSEKLSGQY-AAVFGAPGHTLPPGE--------PALGEVEERCLSPDDSTVKMASPPPSGPPSAAHTPFHQSP-----------------------------VEDKSEPRDFQE-DSWGETKHSPGVSKEDSEE-----------------------------------------------------------------------------------QTVKPGPEEGTSE-EGKGPPTRSPQAQ-----------------------DMPVSIAGGQTGCTIQLLPEQDKAIVFETGEAGSNLG----AGTLPGEVRTSTEEATEPQKDEVLRFTDQSLSPEDAESLSVLSVVSPDTTKQEATPRSPCSL------KEQQPHKDLWPMVSPEDTQSLSFSEESPSKE-----------TSLDISSKQLSPESLGTLQFGELNLGKEERGPVMKAE-----------------DDSCHLAPVSIPEPHRATVSPS-------------TDETPA----------------------GTLPGGSFSHSALSVDRKHSPGEITGPGGHFMTSD------------------------------------------------------------------------------------------------------------------------------------------------------SSLTKSPESLSSPAMEDLAVEWEGKAPG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KEKEPELKSETRQQKGQILPEKVAVVEQDLIIHQKDGALDEENKPGRQQDKTPEQKGRDLDEKDTAAELD-----------------------------------------------------------------------------------------------KGPEPKEKDLDREDQGQ--RAGPPAEKDKASEQRDTDLQQT-QATEPRDRAQERRDSEEKDKSLE------------------------------------------------------------------------------------------------------------------------------------------------LRDRTPEEKDRILVQEDRAPEHSIPEPTQTDRAPDRKGTDDK--EQKEEASEEKEQVLEQKDWALGKEGETLDQEARTAEQKDETLKE-DKTQGQKSSFVEDKTTTSKETVLDQKSAEK---------------------------------------ADSVEQQDGAALEKTRALGLEESPAEGSKAREQEKK-YWKEQDVVQGWRETSPTRGEPVGGQKEPVPAWEGKSPEQEVRYWRDR-DITLQQDAYWRELSCDRKVWFPHELDGQGARPRYCEERESTFLDEGPD-EQEITPLQHTPRSPWTSDFKDFQEPLPQKGLEVERWLAESPVGLPPEEEDKLTRSPFEIISPPASPPEMTGQRVPSA---------PGQESPVPDTESTAPMRNEPTTPSWLAEIPPWVPKDR-----------------------------------------------PLPPAPLSPAPAPPTPAPEPHTPVPFSWGLAEYDSVVAAVQEGAAELEG--------------------GPYSPLGKDYRKAEGEREGEGGAGAPDSSSFSPKVPEAGESLATRDTEQTEPEQREPTPYPDERSFQYADIYEQMMLTGLGPACPTREPPLGASGDWPPHLSTKEEAAGCNTSAEKETSSPASPQNLQS----DTPAFSYASLAGPAVPPRQEPDPGPNVEPSITPPAVPPRAPISLSKDLSPP--------------------------LNGSTVSCSPDRRTPSPKETGRGHWDDGTND--SDLEKGAREQPEKETRSPSPHHPMPMGHSSLWPETEAYSSLSSDSHLGSVRPSLDFPASAFGFSSLQPAPPQLPSPAEPRSAPCGSLAFSGDRALALVP--------------------------GTPTRTRHDEYLEVTKAPSLDSSLPQLPSP--------------------------------------------------------------------------------------------------SSPGGPLLSNLPRPASPALSEGSSSEAT-----------------------TPVISSVAERFPPGLEAAEQSAEGLGSGKESAAHSLWDLTPLSPAPSASLDLAPAPAPAPAPAPGLPGDLGDGTLPCRPECTGELTKKPSPFLSPSGDHEANGPGETSLNPPGFVTATAEKEEAEAPHAWERGSWPEG-----AERSSRPDTLLSSEQPLRPGKSSGGPPCSLSS---------------EVEAGPQGCATDPRPHCGELSPSFLN-----------------------------------------------------------------------------------------------------------------------------------------------------------------------PPLPPSTDDS--------------------------------DLSTEEARLAGKGGRRRVGRPGATGGPCPMADETPPTSASDSGSSQS----------------------DSDVPPETEECPSITAEAALDSDEDGD------------------------------FLPVDKAGGVSG-----THHPRPGHDPPPTPLPDPRPSPPRP---------------------------------------------------------------------------------------DVCMADPEGLSSESGRVERLREK----GRPGRRAPGRAKPASPARRLD-------------------------------------------------------------------------------IRGKRSPTPGKGPVDRTSRTV--------------------------------------------------------------------------PRPRSTPSQVTSAEEKDG---HSPMSKGLVNGLKAGSTALGSKGGS-----------------------------------------------------------------------GPPVYVDLAYIPNHCSGKTADQDFFRRVRASYYVVSGNDPANGEPSRAVLDALLEGKAQWGEN-LQVTLIPTHDTEVTREWYQQTHEQQQQLNVLVLASSS----TVVMQDESFPACKIEF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QYR6-1", "uniprot_id": "MAP1A_MOUSE", "id": "Q9QYR6-1", "name": "Microtubule-associated protein 1A", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDGVAEFSEYVSETVDVPSPFDLLEPPTSGGFLKLSKPCCYIFPGGRGDSALFAVNGFNILVDGGSDRKSCFWKLVRHLDRIDSVLLTHIGADNLPGINGLLQRKVAELEEEQSQGSSSYSDWVKNLISPELGVVFFNVPDKLRLPDASRKAKRS------IEEACLTLQHLNRLGIQAEPLYRVVSNTIEPLTLFHKMGVGRLDMYVLNPVKDSKEMQFLMQKWAGNSKAKTGIVLANGKEAEISVPYLTSITALVVWLPANPTEKIVRVLFPGNAPQNKILEGLEKLRHLDFLRYPVATQKDLAAGAVPANLKPSKIKHRADSK-------------------------------------------ESLKAAPKTAMSKLAKREEVLEEGAKEARSELAKELAKSEKKAKEPSEKPPEKPSKPERVRT----------------------------------------------------ESSEALKAEKRKLIKDKVGKKHLKEKISKLEEKRDKEKKEIKK-------------------------------------ERKELKKEEGRKEEKKDAKKDEKRKDTKPELKKFSKPDLKPFTPEVRKTLYKAKAPGRLK------------------------VDKGRAARGEKELSSEPRTPPAQKGAAPPPAASGHRELALSSP------------------------------------------------------------------------------------------------------------EDLTQDFEELKREERGLLAEPRDTELGEKPLPADASEQGRPSTAIQVTQPPASVLEQE-QVEREKEVVPDFPEDKGSK-------------------------------------------------------------------------------------------------------------NRAPDSGAEVEREKETWEE-------------------RKPREAELTPENIAAAREESEPEVKEDVIEKAELEEMEEVHPSDEEEE-ETKAESFYQKHMQEALKVIPKG--------------------------------------REALGGRELGFQGKAPEKETASFLSSLATPAGAAEHVSYIQDETIPGYSETEQTISDEEIHDE--------------------------------PDERPAPPRFPTSTYDLSGPEGPG------------------------------PFEASQSAESAVPASSSKTYG------APETELTYPPNMVAAPLAEEEHVSS-----------------------------ATSITECDKLSSFATSVAEDQSVASLTAPQTEETGKSSLLLDTVTSIPSS-------------------------------------------------------------------------------------------------------------------RTEATQGLDYVPSAGTISPTSSLEEDKGFKSPPCEDFS----------------------------------------------------------------------------VTGESEKKGESVGRGLTGEKAVGKEEK-----------------------------NVTTSEKLSSQY-AAVFGAPGHALHPGE--------PALGEVEERCLSPDDSTVKMASPPPSGPPSAAHTPFHQSP-----------------------------VEEKSEPQDFQE-DSWGDTKHAPGVSKEDAEE-----------------------------------------------------------------------------------QTVKPGPEEAMSE-EGKVPLSRSPQAQ-----------------------DTLGSLAGGQTGCTIQLLPEQDKAVVFETGEAGAASG----AGSLPGEVR--TQEPAEPQKDELLGFTDQSFSPEDAESLSVLSVVSPDTAKQEATPRSPCTP------KEQQLHKDLWPMVSPEDTQSLSFSEESPSKE-----------TSLDISSKQLSPESLGTLQFGELSLGKEEKGPLVKAE-----------------DNSCHLAPVSIPEPHTATVSPPTD---EAAGEAGLTDESPA----------------------GNLPGSSFSHSALSGDRKHSPGEITGPGGHFMTSD------------------------------------------------------------------------------------------------------------------------------------------------------SSLTKSPESLSSPAMEDLAMEWGGKAPGSEDRATEQ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KEKELERKSETLQQKDQILSEKAALVQRDSVMHQKDEALDEENKPGGQQDKTSEQKGRDLDKKDTAVELG-----------------------------------------------------------------------------------------------KGPEPKGKDLYLEDQG-------LAEKDKALEQRGAALQQT-QAPEPRARAQEHRDLEQKDEHLE------------------------------------------------------------------------------------------------------------------------------------------------LRDKTPEEKDKVLVLEDRAPEHIIPQPTQTDRAPEHRSKVDK--EQKDEASEEKEQVLEQKDWAREKEGAALDQDNRAAGQKDGTLKE-DKTQGQKSSFLEDKSTTPKEMTLDQKSPEK---------------------------------------AKGVEQQDGAVPEKTRALGLEESPEEEGKAREQEEK-YWKEQDVVQGWRETSPTRGE-------PVPAWEGKSPEQEVRYWRDR-DITLQQDAYWKELSCERKVWFPHELDGQGARPRYSEERESTFLDEGPN-EQEITPLQHTPRSPWASDFKDFQEPLPQKGLEVERWLAESPVGLPPEEEDKLTRSPFEIISPPASPPEMTGQRVPSA---------PGQESPVPDTKSTPPTRNEPTTPSWLAEIPPWVPKDR-----------------------------------------------PLPPAPLSPAPAPPTPAPDPHAPAPFSWGIAEYDSVVAAVQEGAAELEG--------------------GPYSPLGKDYRKAEGEREGEGGAGAPDSSSFSSKVPEVTESHTTRDAEQTEPEQREPTPYPDERSFQYADIYEQMMLTGLGPACPTREPPLGASGDWPPHLSTKEEAAGRNKSAEKELSSAVSPPNLHS----DTPTFSYASLAGPTIPPRQEPEPGPNVEPSFTPPAVPPRAPISLSQDPSPP--------------------------LNGSTTSCGPDRRTPSPKEAGRSHWDDGTND--SDLEKGAREQPEKETQSPSPHHPMPVGHPSLWPETEAHSSLSSDSHLGPVRPSLDFPASAFGFSSLQPAPPQLPSPAEPRSAPCGSLAFSGDRALALVP--------------------------GTPTRTRHDEYLEVTKAPSLDSSLPQLPSP--------------------------------------------------------------------------------------------------SSPGAPLLSNLPRPASPALSEGSSSEAT-----------------------TPVISSVAERFPPGLEVAEQSSGELGPGNEPAAHSLWDLTPLSPAPLASRDLAPAPAPAPAPS--LPGNLGDGTLSCRPECSGELTKKPSPFLSHSGDHEANGPGETSLNPPGFATATAEKEEAEALHAWERGSWPEG-----AERSSRPDTLLSSEQ--RPGKSSGGPPCSLSS---------------EVEAGPQGCATDPRPHCGELSPSFLN-----------------------------------------------------------------------------------------------------------------------------------------------------------------------PPLPPSTDDS--------------------------------DLSTEEARLAGKGGRRRAGRPGATGGPCPMADETPPTSASDSGSSQS----------------------DSDVPPETEECPSITAEAALDSDEDGD------------------------------FLPVDKAGGVSG-----THHPRPGHDPPPAPLPDPRPPPPRP---------------------------------------------------------------------------------------DVCMADPEGLSSESGRVERLREKV--QGRPGRKAPGRAKPASPARRLD-------------------------------------------------------------------------------IRGKRSPTPGKGPVDRTSRAL--------------------------------------------------------------------------PRPRSTPSQVTS-EEKDG---HSPMSKGLVNGLKAGSTALGSKGSS-----------------------------------------------------------------------GPPVYVDLAYIPNHCSGKTADQDFFRRVRASYYVVSGNDPANGEPSRAVLDALLEGKAQWGEN-LQVTLIPTHDTEVTREWYQQTHEQQQQLNVLVLASSS----TVVMQDESFPACKIEF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P78559-1", "uniprot_id": "MAP1A_HUMAN", "id": "P78559-1", "name": "Microtubule-associated protein 1A", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDGVAEFSEYVSETVDVPSPFDLLEPPTSGGFLKLSKPCCYIFPGGRGDSALFAVNGFNILVDGGSDRKSCFWKLVRHLDRIDSVLLTHIGADNLPGINGLLQRKVAELEEEQSQGSSSYSDWVKNLISPELGVVFFNVPEKLRLPDASRKAKRS------IEEACLTLQHLNRLGIQAEPLYRVVSNTIEPLTLFHKMGVGRLDMYVLNPVKDSKEMQFLMQKWAGNSKAKTGIVLPNGKEAEISVPYLTSITALVVWLPANPTEKIVRVLFPGNAPQNKILEGLEKLRHLDFLRYPVATQKDLASGAVPTNLKPSKIKQRADSK-------------------------------------------ESLKATTKTAVSKLAKREEVVEEGAKEARSELAKELAKTEKKAKESSEKPPEKPAKPERVKT----------------------------------------------------ESSEALKAEKRKLIKDKVGKKHLKEKISKLEEKKDKEKKEIKK-------------------------------------ERKELKKDEGRKEEKKDAKKEEKRKDTKPELKKISKPDLKPFTPEVRKTLYKAKVPGRVK------------------------IDRSRAIRGEKELSSEPQTPPAQKGTVPLPTISGHRELVLSSP------------------------------------------------------------------------------------------------------------EDLTQDFEEMKREERALLAEQRDTGLGDKPFPLDTAEEGPPSTAIQGTPPSVPGLGQEEHVMKEKELVPEVPEEQGSK-------------------------------------------------------------------------------------------------------------DRGLDSGAETEEEKDTWEE-------------------KKQREAERLPDR-TEAREESEPEVKEDVIEKAELEEMEEVHPSDEEEEDATKAEGFYQKHMQEPLKVTPRS--------------------------------------REAFGGRELGLQGKAPEKETSLFLSSLTTPAGATEHVSYIQDETIPGYSETEQTISDEEIHDE--------------------------------PEERPAPPRFHTSTYDLPGPEGAG------------------------------PFEASQPADSAVPATSGKVYG------TPETELTYPTNIVAAPLAEEEHVSS-----------------------------ATSITECDKLSSFATSVAEDQSVASLTAPQTEETGKSSLLLDTVTSIPSS-------------------------------------------------------------------------------------------------------------------RTEATQGLDYVPSAGTISPTSSLEEDKGFKSPPCEDFS----------------------------------------------------------------------------VTGESEKRGEIIGKGLSGERAVEEEEEET--------------------------ANVEMSEKLCSQYGTPVFSAPGHALHPGE--------PALGEAEERCLSPDDSTVKMASPPPSGPPSATHTPFHQSP-----------------------------VEEKSEPQDFQEADSWGDTKRTPGVGKEDAAE-----------------------------------------------------------------------------------ETVKPGPEEGTLEKEEKVPPPRSPQAQ-----------------------EAPVNIDEGLTGCTIQLLPAQDKAIVFEIMEAGEPTGPILGAEALPGGLRTLPQEPGKPQKDEVLRYPDRSLSPEDAESLSVLSVPSPDTANQEPTPKSPCGL------TEQYLHKDRWPEVSPEDTQSLSLSEESPSKE-----------TSLDVSSKQLSPESLGTLQFGELNLGKEEMGHLMQAE-----------------DTSHHTAPMSVPEPHAATASPPTDGTTRYSAQTDITDDSLD----------------------RKSPASSFSHSTPSGNGKYLPGAITSPDEHILTPD------------------------------------------------------------------------------------------------------------------------------------------------------SSFSKSPESLPGPALEDIAIKWEDKVPGLKDRTSE-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QKKEPEPKDEVLQQKDKTLEHKEVVEPKDTAIYQKDEALHVKNEAVKQQDKALEQKGRDLEQKDTALEQKD----------------------------------------------------------------------------------------------KALEPKDKDLEEKDKALEQKDKIPEEKDKALEQKDTALEQKDKALEPKD-----KDLEQKDRVLE------------------------------------------------------------------------------------------------------------------------------------------------QKEKIPEEKDKALDQKVRSVEHKAPEDTVAEMKDRDLEQTDKAPEQKHQAQEQKDKVSEKKDQALEQKYWALGQKDEALEQNIQALEENHQTQEQESLVQEDK--TRKPKMLEEKSPEK---------------------------------------VKAMEEKLEALLEKTKALGLEESLVQEGRAREQEEK-YWRGQDVVQEWQETSPTREEPAGEQKELAPAWEDTSPEQDNRYWRGREDVALEQDTYWRELSCERKVWFPHELDGQGARPHYTEERESTFLDEGPDDEQEVPLREHATRSPWASDFKDFQESSPQKGLEVERWLAESPVGLPPEEEDKLTRSPFEIISPPASPPEMVGQRVPSA---------PGQESPIPDPKLMPHMKNEPTTPSWLADIPPWVPKDR-----------------------------------------------PLPPAPLSPAPGPPTPAPESHTPAPFSWGTAEYDSVVAAVQEGAAELEG--------------------GPYSPLGKDYRKAEGEREEEGRAEAPDKSSHSSKVPEASKSHATTEPEQTEPEQREPTPYPDERSFQYADIYEQMMLTGLGPACPTREPPLGAAGDWPPCLSTKEAAAGRNTSAEKELSSPISPKSLQS----DTPTFSYAALAGPTVPPR--PEPGPSMEPSLTPPAVPPRAPI-LSKGPSPP--------------------------LNGNILSCSPDRRSPSPKESGRSHWDDSTSD--SELEKGAREQPEKEAQSPSPPHPIPMGSPTLWPETEAHVSPPLDSHLGPARPSLDFPASAFGFSSLQPAPPQLPSPAEPRSAPCGSLAFSGDRALALAP--------------------------GPPTRTRHDEYLEVTKAPSLDSSLPQLPSP--------------------------------------------------------------------------------------------------SSPGAPLLSNLPRPASPALSEGSSSEAT-----------------------TPVISSVAERFSPSLEAAEQESGELDPGMEPAAHSLWDLTPLSPAPPASLDLALAPAPS------LPGDMGDGILPCHLECSEAATEKPSPFQVPSEDCAANGPTETSPNPPGPAPAKAENEEAAACPAWERGAWPEG-----AERSSRPDTLLSPEQPVCPAGGSGGPPSSASP---------------EVEAGPQGCATEPRPHRGELSPSFLN-----------------------------------------------------------------------------------------------------------------------------------------------------------------------PPLPPSIDDR--------------------------------DLSTEEVRLVGRGGRRRVGGPGTTGGPCPVTDETPPTSASDSGSSQS----------------------DSDVPPETEECPSITAEAALDSDEDGD------------------------------FLPVDKAGGVSG-----THHPRPGHDPPPLPQPDPRPSPPRP---------------------------------------------------------------------------------------DVCMADPEGLSSESGRVERLREKEKVQGRVGRRAPGKAKPASPARRLD-------------------------------------------------------------------------------LRGKRSPTPGKGPADRASRAP--------------------------------------------------------------------------PRPRSTTSQVTPAEEKDG---HSPMSKGLVNGLKAGPMALSSKGSS-----------------------------------------------------------------------GAPVYVDLAYIPNHCSGKTADLDFFRRVRASYYVVSGNDPANGEPSRAVLDALLEGKAQWGEN-LQVTLIPTHDTEVTREWYQQTHEQQQQLNVLVLASSS----TVVMQDESFPACKIEF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1QUZ1-1", "uniprot_id": "A0A8M1QUZ1_DANRE", "id": "A0A8M1QUZ1-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------MLIVIGDISTDHELDSVKEHIKRGILSWDIDLTFCDLNKELKLFQARHSAQFSSEVKGQRLLQYKSDILETVVLVNPSEENIAIEIRTLVCDSAGHKLLVLSGQSTDRSGDIILQSGAFGWKNLSDILSSRRIKDLLNQPYSGQQACLTVFCKGEGGWSSLGYVQ-EQSILKYRLNPEPVLPEMEGVSEFTEYVSETVDVPSPFELLEPPTSGGFLKLSKPCCYIFPGGRGDSALFAVNGFNILIDGGSDRKSCFWKLVRHLDRIDSVLLTHIGADNLPGINGLLQRKIAEQEEEKIHGLNTYGDWMKNLISPELGVVFFNVPEKLKMPESTLKAKRS------IEEASLTLQYLHKLGIKPEPLYRVVSNTIEPLTLFHKLGVGKLDMYILNPLKDSKEMQFFMQKWAGNSKAKTGIVLANGKEGEISVPYLTSVTALVVWVPASPTEKIVRVLFPGNAPQNKIFEGLEKLRHLDFLRYPVATQKDMSSGAPPPLIKQTKMKLRTDSK-------------------------------------------ESLKSSPKMSSTTKASKKEANEDIESKSESVKENKAEKKEKKMKET-----VKAPKPLKPKT----------------------------------------------------ASPDSLKLEKKKLQREKSPKKHVKEKASKMEEKKDLEKKDTKK-------------------------------------EKTEVKKDD---ILKKEKK-----DKVKPELKKITKPDLKPFTPEVRKTLNKAKVQVKPK------------------------TEKTKAAK------EQENRPAAKQASV--EKQE-IDRSLVSSP------------------------------------------------------------------------------------------------------------EDLTKDFEALRLEEELSKSIESK-ILPKVQSAVDTVVPHIESPDEGINTTDVETESPLEERVPYGANANKFASKIT---------------------------------------------------------------------------------------------------------------DRFEDEGAATEY--------------------------DHTTGLKGAKTSDLARMG----------EDAMKPKRSDSE----EDEDVIEKAELEDAEDI--VHEEELKY--------------------------------------KSDESRKEK----LGKDWETKSEIKSTKS-LGAADHVSLIQDETIPGYSETEQTLSDEEINEE--------------------------------TEERIPHLQYDVGSYDISVPDEPG------------------------------TFDTIHGMKPPTISVASEFSSKGFAVDQEPVLSAYATNIVAAPLAEEEHISS-----------------------------ATSITEYDKLSSFATSVTEDQSIASVTAPPTEDAGKSSLLLDTINSIPSSI------------------------------------------------------------------------------------------------------------------QTDATQGKEYLHSAGTISPTSSLEEDKCFKSPPSEEYQPIVPETETTVKATAPTNYE-----------------------------------------------DEEDEEEDEDQTPNVDMPLGKIHEGYASAAILQDTEKASDKIHSSMAPIP----------PPAMYVGTQERDEKASFEHKSKLSSPEKILSFSPNLPCTSEVNITSESEERCLSPDDSTVRFASPTQSGPTSGSYSPT---------------------------------EERSQKPLTVDKEEKLDKETVDSYLTKDATSD---------------------------------------------------------------------------KKSVKIIDDEVDPFVKEFSSTKTAKFDLEDEEEED---------------------YYGKETYKVCGKT-------KYKEERECTFLDEEYS--------------------QEAKPLKEEKLFENKKESVEK----------ESLNDKPQNVTSLG-----------------------HEHKSQMLSSGEEDESET-----------EDGVYSSIKAPQGKLDSMSAS----QGKKDVSFSETD-----------------DQN-------------VSKDSDK--------------------------------------------SVHFNLYSFPEGEKGLRGEIERVVRQDT---------------------------------------------------------------------------------------------------------------------------------------------------------PYVGKSFTYSDVYD--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SKSSSVDSYSPNLP------------------------------VEHTFDDTDVTPKKTE-----------------------------------------------------------------------------------------------------------QEDSLDSS------------------------------------TVKFSDPKATDE-----------------------------------------------------------------------------------------------------------------------------------------------KQTSDSYSKTQSTYMTPQFRDS-------------------------------------------------------SEATFSEKINKTEERTFEKTS-------------PISAEKDP------------------------------------------------LSVQFEKPDFTGMMEVSASQSTHYEADR--LISD----YSAKSTSCSLGQSTFGPKEVMAGDMKMFADGEDEDEDEEEDEDDEDEEYGEHAS---------------------------------DSDTEKGAKEKDAEYP----MKKVISPVPTQFQDEKKDTVTHDN----------------------------TRSLGSE---------DYG----------------------------KSLGSS-------------------------------------------------TFDTQSKGAASSYPVESHIKCFSG------FEHSSS------EEKD------------------------EFVENHDKVVKS----YLPLSTKTAEDKCSHYDDKDLEFD--KQQTSDAVEKKTGDP-----------------VSLGLGYTTMSATAYSSSSSYSHSSSASASLSTSRQFGDELEAQACTG------------FDYSSFKDEHSPVNDSPFSSSSGQAKDGYLEVSEKLTPATTTAESTS--------------------------SLARFSPLSPFEEIKPFPPHAGTCVVDKKESTYTGSN-----ISDQGLQSQCFYKPEWDEDSRLQAELGATGPFS----SVPPATQKDTLPRDLCGASS--------------TLEFEKQYYEETESSEEED--------------------------DYMYETEQDK---LQYQRSPVTAQADKKD-----------------------------------------------------------------------------------------------------DTFSLSETLSKDISSSLGGAISNMHT-----------------------SYSLSFPEPTKPDTTNGPAEVSLTAAEAFGGACKVETNLS-KVEMKGQEFDIKKIRSPS----KWQMQQPRDIYPGASPPHYRHEDEYDEE-----EETEPEHPARPLSLSSTEKPFQSSYYTD-------------------DPNKHDDDSDYPSNVGVRPHSS---------------------------TASPGYSACENKQRRGDTSPSFIN-----------------------------------------------------------------------------------------------------------------------------------------------------------------------PSLCQLSSDEENEEQTSQAS------DQQQPVGKTRFHKQPQDYSHSHHCEDNELQHFSG---AMAAGISASGEDTPPTSISEPLHSQS----------------------DSDVPPGTEECPSITAKGN-DSDDDAD------------------------------YLPVDKSSGAYGGKHYLSRSPDKNHDPLPSPLMDPAPYPPHP---------------------------------------------------------------------------------------DACMVDPEALSS---LTDKPIKKD--TKAKGLRKLGKTKSSSPARKAD-------------------------------------------------------------------------------ARRKRSP------SKEPFAHT--------------------------------------------------------------------------TSLRKKDMEDDLSRSSHN------TGKGLVNGLKNTAGSNSSKFSTAVPP-------------------------------------------------------------------GPPIYVDLAYIPNHCSAKNVDQEFFKRVRSAYYVVSGNDSSNGEPSRSVLDALLEGKAQWGSN-LQVTLIPTHDTEVTREWYQQTHEKQQELNIMVLASSS----TVVMQDESFPACKIEF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AC58IY35-1", "uniprot_id": "A0AC58IY35_DANRE", "id": "A0AC58IY35-1", "name": "", "aln": "--------------------MSCRVCVLRSQSCVLFGQSDGGKQRVSSALLALTVRSGQLAAVVMEMSAGPSSVRGAVPAESPPRGSLVAAAEDDEH-----REQPLPEQTARSGDFYMLIVIGEIATEQQLQTARLHIERGIRSWDISVSECDLDQQLQLFITRHSAQFSAEVRGQRTLQHKSDVLETVVLVNPSEDTVISEIHCLVSDPAVHKLLVLSGQSSDQ-GDLVLQTGVFSHQTFLRVFAEPGVSHLLGKASSGQRASLTVSCRSDAGWSSLGQQQRIRELLNYTLNPEPILPKMEGVTEFTEYISETVDVPSPFDLLEPPTSGGFLKLSKPCCYIFPGGRGDSALFAVNGFNILIDGGSDRRSCFWKLVRHLDRIDSVLLTHIGADNLPGINGLLQRKVAEQEEEQSQGSTTYSDWMKNLISPELGVVFFNVPEKLRTSESNLKVKRS------IEEASLTLQYLNKLGIKPEPLFRVVSNTIEPITLFHKMGVGRLDMFVLNPVKDSKEMQFLMQKWAGNSKAKTGIILPNGKEGEISVPYLTSITALVVWLPASPTEKIVRVLFPGNAPQNKILEGLEKLKHLDFLRYPVATQKDINSGVSPSAVKQTKLKQRTDSK-------------------------------------------ESLKSSPKTHTPAKPSKKETDEHEDVSVVETKSDSVKENKVEKKEE-----KKHTKSLKPKA----------------------------------------------------EVT-----EKKKLLKEKPLKKHPKERLSKMDEKKDKEKREIKK-------------------------------------EKRVIKQDD---SVKKDEKKMKAKDSSKPELRKITKPELKPFTPEVRKTLHKAKTQGKPK------------------------SIKKKPTTAKAEIAEITAEPVAEKTEP--EKQENGTVEDISAP------------------------------------------------------------------------------------------------------------EDLTKDLNKIKPTEVTSQSESPKSDLTVSELPAEKDIEPSKSAEDKVGETDMVEQKTKVEEVSASAGIKEVSSAAVKEKDEPQTSEI----------------------------------------------------------------------------------------------------EKFEDEGAAIEDEDEEEIDIQPVKKKTDDEEEEDMGIGDEEDEGPAKETKDLEGVDRKHEVEEMEKQKQVEERRIEAEDEQFEEEDVIEKAELEEAEDLDAIADEEIKE--------------------------------------LSPEKVKDEEDAYMSNVGGVTAGITSTAQGAAAAENLSYIQDETIPGYSETEQTISDEEIHEE--------------------------------AEDRIPHLQYEVGSYDVSVPDQPG------------------------------SFDAMHGMREMQAAAMGNGTSKVFMGAQEPAISIYTS-ILAAPLAEEEHVSS-----------------------------ATSITEYDKLSSLPTSIAEDQSVASVTAPQTEDTGKSSLVLDTVQPIT---------------------------------------------------------------------------------------------------------------------QTEATQGKDYLHSAGTISPTSSLEEDKCFKSSPSDESPPLPLEGKTEGIEMAAHYDD-----------------------------------------------EEEDE---YDQTPNVDISLEKLQEGYASPDKLEHKDKEMDKPKSPVPLVPDMSTFEKSSIPETEKASVASPKEDMSFKEQAILSSSSHSVSKLP----VSEASVYPEVEDRCVSPDDSTVKMASPTHSGPPSASHSPLRMSPVEGKDKVLLKDTHQEQGVPISPTEFKFEKKNEKQESDILDEKEKPQAEKEEKNIIQKAVTAPSPLVDDVLAKKESESVPPPKDVSDTK-----------------------------------EIPDPSVEKKVEVKEGLKEAEDKDSKLSDDHDVEETCDLKLSTEKKEQEKQKEGEGDAEEKYNDKDEFLKYAEVTDKGAGKSEVEKATQPSKEDFDKKNANEEFQDKGYLAVLEGLEIEKQVKQVEEIQPEKPEISSKLDKESKEKDVTGASCQFLESLDIKAETSTSPESTKIDTETHGTKETDIKTKPEKTSQQKPESIDTTTEQVALT-----------ETDSFVSIAQFTEDTDSLKSKTQQLGEKTDVTLKKEK-----------------AESKSVTDLTFESITTAAKEHDKSWNENVEEVKSSTQVQISPLKTDVQSTEMHVDMSIMEKDISSKDDEEFKLKTTQEMEEHISGEISPETKMTSEKDEVLEQKLIE---------------------------------------------------------------------------------------------------------------------------ETQNTQQLQKADISSKAEPQMSHSTVSEDTEDGHQISQDIEKSVEDIKCKTQISISENLDFPPTVDQESKAKKADLSQDQVSLVESEKLDLSAEGDQECKKAVEIPSKPDEESIECQIYEKKDELSISKSVFEPEVQSEFQPVTSDKEGLH---------------------------------------------TKEDESNKVTFVKSEQSVEFEEISSKPYESKYKFVEETQLQVSKDQSVPESSITVAKKDQLYEEKQTEETVTKAPQSSMETNVPPDTKQEFEATSVEDKKTELILSESKTVDSKAEHDTLETETKSEITTVEDKTTESKVSKETEEKILKEDASKLVLDEPDTKMDLGAKEKSLVENLERTRKTSDLDCKEKEETKEHKEDINIDTSLQETDTFQSSDIGFKLNLDYKEKFIEETPSTVEKTKDGKSAFETTFPTKFSDEDESTEEDEGD-------------------------------------------------------------AVCMGGAGSRPLSVEPWKSEELKENISAQPSEPSIQKEEIIAHSEELTKGCSEKSTEPEECKVDATSIVLSTANTSSKAVSEILTETKPTSITLLCSDSQTSGVDGQHETLFSKGAAKPEKEAEREWEGEREVASPVLESHSDFQKSDGADEKCSEKAESERMKSNDKVTYEVEKESYEASKYEPYEKPISKDSDKEREEEDQYPGMDRDLDYIRKTSQAMELG---------ATCSVEEHSDDEPVSFSKVDYQTSPSIYSSQSAYSEQDNKDLYQEEELVREERLDTSVDSSSTYESKDTLAAGSSFCASSDTQDISEKLEREEKEKEKEDTHSSLLSKLDGSHVQLSDIEPCTSA--SSFSKPDVQDRDHRRDQVEETMATPHLEDLDKTKPPLTQDFTPQGLLTSSQDQSVQGLTTSSASAYDENKTGSTISGEGKDKNKLGSD---------DSKDDPFSSGRYSPPEKDLLPARVLPEDPCTATPGSSGQSVNVDDNVLAFECTAKTDLVASKPLVVSTEEEECMVRSQKIFAEEEDDFEDEEEEDASDLDIEKGARELSEKESKAVFDTTSASKSPEGKEKDSVSSLV--------------YGGTAEVPQTGKIVDSSTDKTESLTTKLSSVQGEQYEVIDKQFEKSKEEDTSSVQSETSKPSDDKHEPQRTDKKPEVSESLTATQAPMSDGTYSSSSSISYSSSTSASYSTGQHIGDGLDTHINVPSFQLRSDGDTVSYEYSSLKEEESPTMDLPCLK-----KDEYMEVSDRMTHATTTAESIS--------------------------SLARFSPLSPLEESKSFLQDQISSAEEKSEEDMSSIKSDKDHVSDPKHVEPPFSKMPESETSKHAAQTTEVASTTSLKFEIAPLEKADSKEKHSEEKSSDDEPENNKSDFEEGTLPCRIECDKSSSSEQHTD--------------------------ANVFSTKTLHSFELKCSSEPTEMASSQNVPV---------------------------------------------------------------------------------------------MACGTLSTSTLSEQIVKQEWEEMSEKIKDLPE-----------------------KVEERFDMKEETLSQAKCEEVIVKHKEIEDEQIHPEKKCDVRSEKMGEILDGKKSENKSESEGKPKESEEKEEVKQAEIVVEKESKEKDKESKKQTEEIIMEKYSKNVPESSQHTAISSTMEHEDIVCLKAPPGYGEDVYEDIDREESDEEREVKYDSKERPSSPPSGAQACYAEVSKKADEGFTRPSDLSMEATSSHSPSLFKHRKGDISPSFIN-----------------------------------------------------------------------------------------------------------------------------------------------------------------------PSPHDLSSEEGDDDARSDHSRDDDGDEREQHSVKRRSHKQQHHHPQSRQEEGKEGSHSIMGGTSTGHGIMLAGEETPPTSLSESLPSQS----------------------DSDVPPETEECPSITAEGNLDSDEDAE------------------------------HLPVDKMSAAGGSGGSHHSSSPRSHDPPPIPMKDPLPHPPHP---------------------------------------------------------------------------------------DVCMIDPEALLNGQIHTERPVKKD--LKTNRGLRKTLGKSASPARKGD-------------------------------------------------------------------------------AKTRRSTTPVKQTSKDSSPHT--------------------------------------------------------------------------LKRKDSEKTFRLTKMSETEGSRGDSGRGLVNGVKSNAASN-LKSNAGTPP-------------------------------------------------------------------GPPIYVDLAYIPNHCSAKNVDQEFFKRVRAAYYVVSGNDPGSGEPSRAVLDALLEGKAQWGTN-LQVTLIPTHDTEVTRDWYQQTHEKQQDLNIMVLASSS----TVVMQDESFPACKIEF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W596-1", "uniprot_id": "FUTSC_DROME", "id": "Q9W596-1", "name": "Microtubule-associated protein futsch", "aln": "MGDQPKATTTATGGAAGPVPEGDAVMATTNQDALAKGAGDGPAQDAAQEPGQAEHGEPGDGGDGGDDGATDAGASSLPPSEIGGRAPLDTACSDADGGAPSSLAGGIVGPPSPLTGCYLLIVLGEPHSEEHKDNILQHLLKGFLSWDVSDCHVDLEEELN-TITQHAPEGEEARHGERLIQYASENLVTEVLIHPQYNTLIQCMRNLLSSFTRHRHIIHAGYTFSGNGSWILQDGTFSVADFSEAFQEHDVQRVIR--AYADTITMNIHCADAGLWHTLPEKAFARQCRIRINPVDVLDTSSECINGFIDYLAPMVMPTSLRELLETSDVVGNIRFTHPTLYVFPGGQGDAALFGINGFNMLVDGGFNRKACFWDFARHLDRLDAVLMTRLNNSNVQGLGAVVSRKRD------------------AHVYPQIGHFFGNVPDRKGLPSPDGDKDRDPLLIDLFERGHGIVSDLKALDLKPQCCYRNQ----EPVNLYHKVGHGTLDMYVISPARDSKEVKEFLQKWHAGD--QRLFAARDSRDFNFPLQNLVSICALLVWQPANPDDTITRILFPGSTPDFKIQEGLEKLKHLEFMKHSTCTAKSIAPAIQTVTSTRKSLKSAIEATPAPPSASYKTTKFSPVASAALAVQHPQQQDNKAKEAAAAAAAAAAAAASAATIARAKADSMDTDAEPEHEADPEPADTGDEAAPTEQEPEAETEPEPEHEPEAEQDKDVGEEKKVEVLIMKPQQATPAVIAASGKDGVDAASADATPTGKLSKASAKGKADKPRAEVKPVVRSRIDTKPPKSMDRKLAKRDEKKSSPTTTPAARAPVAQNAKPKVLSRPATKSSPSSTPAKSAKEANNRKVLESKQQAARVQATSTVSRRVTSTASERRVQQQAEAKTAATGATQATQRKPISRRPRGVSPSKRAPAPGSPVKQAKPKAADLKKTRLDKGGTTDSSLVSTPSADEATAAKKLQDLTASQELDAEKQRELDDLKEEQEVVREIEAVFSRDEMKRQQHQQIKAELREMPAEGTGDGENEPDEEEEYLIIEKEEVEQYTEDSIVEQESSMTKEEEIQKHQRDSQESEKKRKKSAEEEIEAAIAKVEAAERKARLEGASARQDESELDVEPEQSKIKAEVQDIIATAKDIAKSRTEEQLAKPAEEELSSPTPEEKLSKKTSDTKDDQIGAPVDVLPVNLQESLPEEKFSATIESGATTAPTLPEDERIPLDQIKEDLVIEEKYVKEETKEAEAIVVATVQTLPEAAPLAIDTILASATKDAPKDANAEALGELPDSGERVLPMKMTFEAQQNLLRDVIKTPDEVADLPVHEEADLGLYEKDSQDAGAKSISHKEESAKEEKETDDEKENKVGEIELGDEPNKVDISHVLLKESVQEVAEKVVVIETTVEKKQEEIVEATTVITQENQEDLMEQVKDKEEHEQKIESGIITEKEAKKSASTPEEKETSDITSDDELPAQLADPTTVPPKSAKDREDTGSIESPPTIEEAIEVEVQAKQEAQKPVPAPEEAIKTEKSPLASKETSRPESATGSVKEDTEQTKSKKSPVPSRPESEAKDKKSPFASGEASRPESVAESVKDEAGKAESRRESIAKTHKDESSLDKAKEQESRRESLAESIKPESGIDEKSALASKEASRPESVTDKSKEPSRRESIAESLKAESTKDEKSAPPSKEASRPGSVVESVKDETEKSKEPSRRESIAESAKPPIEFREVSRPESVIDGIKDESAKPESRRDSPLASKEASRPESVLESVKDEPIKSTEKSRRESVAESFKADSTKDEKSPLTSKDISRPESAVENVMDAVGSAERSQPESVTASRDVSRPESVAESEKDDTDKPESVVESVIPASDVVEIEKGAADKEKGVFVSLEIGKPDSPSEVISRPGPVVESVKPESRRESSTEIVLPCHAEDSKEPSRPESKVECLKDESEVLKGSTRRESVAESDKSSQPFKETSRPESAVGSMKDESMSKEPSRRESVKDGAAQSRETSRPASVAESAKDGADDLKELSRPESTTQSKEAGSIKDEKSPLASEEASRPASVAESVKDEAEKSKEESRRESVAEKSPLPSKEASRPASVAESIKDEAEKSKEESRRESVAEKSPLPSKEASRPASVAESIKDEAEKSKEESRRESVAEKSPLPSKEASRPASVAESIKDEAEKSKEESRRESVAEKSPLPSKEASRPASVAESIKDEAEKSKEESRRESVAEKSPLPSKEASRPASVAESIKDEAEKSKEESRRESVAEKSPLPSKEASRPASVAESIKDEAEKSKEESRRESVAEKSPLPSKEASRPASVAESIKDEAEKSKEETRRESVAEKSPLPSKEASRPASVAESIKDEAEKSKEESRRESAAEKSPLPSKEASRPASVAESVKDEADKSKEESRRESMAESGKAQSIKGDQSPLKEVSRPESVAESVKDDPVKSKEPSRRESVAGSVTADSARDDQSPLESKGASRPESVVDSVKDEAEKQESRRESKTESVIPPKAKDDKSPKEVLQPVSMTETIREDADQPMKPSQAESRRESIAESIKASSPRDEKSPLASKEASRPGSVAESIKYDLDKPQIIKDDKSTEHSRRESLEDKSAVTSEKSVSRPLSVASDHEAAVAIEDDAKSSISPKDKSRPGFVAETVSSPIEEATMEFSKIEVVEKSSLALSLQGGSGGKLQTDSSPVDVAEGDFSHAVASVSTVTPTLTKPAELAQIGAAKTVSSPLDEALRTPSAPEHISRADSPAECASEEIASQDKSPQVLKESSRPAWVAESKDDAAQLKSSVEDLRSPVASTEISRPASAGETASSPIEEAPKDFAEFEQAEKAVLPLTIELKGNLPTLSSPVDVAHGDFPQTSTPTSSPTVASVQPAELSKVDIEKTASSPIDEAPKSLIGCPAEERPESPAESAKDAAESVEKSKDASRPPSVVESTKADSTKGDISPSPESVLEGPKDDVEKSKESSRPPSVSASITGDSTKDVSRPASVVESVKDEHDKAESRRESIAKVESVIDEAGKSDSKSSSQDSQKDEKSTLASKEASRRESVVESSKDDAEKSESRPESVIASGEPVPRESKSPLDSKDTSRPGSMVESVTAEDEKSEQQSRRESVAESVKADTKKDGKSQEASRPSSVDELLKDDDEKQESRRQSITGSHKAMSTMGDESPMDKADKSKEPSRPESVAESIKHENTKDEESPLGSRRDSVAESIKSDITKGEKSPLPSKEVSRPESVVGSIKDEKAESRRESVAESVKPESSKDATSAPPSKEHSRPESVLGSLKDEGDKTTSRRVSVADSIKDEKSLLVSQEASRPESEAESLKDAAAPSQETSRPESVTESVKDGKSPVASKEASRPASVAENAKDSADESKEQRPESLPQSKAGSIKDEKSPLASKDEAEKSKEESRRESVAEQFPLVSKEVSRPASVAESVKDEAEKSKEESPLMSKEASRPASVAGSVKDEAEKSKEESRRESVAEKSPLPSKEASRPASVAESVKDEADKSKEESRRESGAEKSPLASKEASRPASVAESIKDEAEKSKEESRRESVAEKSPLPSKEASRPTSVAESVKDEAEKSKEESRRDSVAEKSPLASKEASRPASVAESVQDEAEKSKEESRRESVAEKSPLASKEASRPASVAESIKDEAEKSKEESRRESVAEKSPLASKEASRPTSVAESVKDEAEKSKEESSRDSVAEKSPLASKEASRPASVAESVQDEAEKSKEESRRESVAEKSPLASKEASRPASVAESVKDDAEKSKEESRRESVAEKSPLASKEASRPASVAESVKDEAEKSKEESRRESVAEKSPLPSKEASRPTSVAESVKDEAEKSKEESRRESVAEKSSLASKKASRPASVAESVKDEAEKSKEESRRESVAEKSPLASKEASRPASVAESVKDEAEKSKEESRRESVAEKSPLPSKEASRPTSVAESVKDEADKSKEESRRESGAEKSPLASMEASRPTSVAESVKDETEKSKEESRRESVTEKSPLPSKEASRPTSVAESVKDEAEKSKEESRRESVAEKSPLASKESSRPASVAESIKDEAEGTKQESRRESMPESGKAESIKGDQSSLASKETSRPDSVVESVKDETEKPEGSAIDKSQVASRPESVAVSAKDEKSPLHSRPESVADKSPDASKEASRSLSVAETASSPIEEGPRSIADLSLPLNLTGEAKGKLPTLSSPIDVAEGDFLEVKAESSPRPAVLSKPAEFSQPDTGHTASTPVDEASPVLEEIEVVEQHTTSGVGATGATAETDLLDLTETKSETVTKQSETTLFETLTSKVESKVEVLESSVKQVEEKVQTSVKQAETTVTDSLEQLTKKSSEQLTEIKSVLDTNFEEVAKIVADVAKVLKSDKDITDIIPDFDERQLEEKLKSTADTEEESDKSTRDEKSLEISVKVEIESEKSSPDQKSGPISIEEKDKIEQSEKAQLRQGILTSSRPESVASQPESVPSPSQSAASHEHKEVELSESHKAEKSSRPESVASQVSEKDMKTSRPASSTSQFSTKEGDEETTESLLHSLTTTETVETKQMEEKSSFESVSTSVTKSTVLSSQSTVQLREESTSESLSSSLKVEDSSRRESLSSLLAEKGGIATNTSLKEDTSASASQLEELLVQSEECSSESIVSEIQTSIAQKSNKEIKDARETKVTSQFTTTTSSATKDDSLKETVAEFLATEKIVSAKEAFSTEATKSADDCLKKTTASAVSSTSASQRALFVGTDESRRESLLSQASESRLTHSDPEDEEPADDVDERSSVKESRSKSIATIMMTSIYKPSEDMEPISKLVEEEHEHVEELAQEVTSTSKTTTLLQSSEQSSTTTSSTSKTGASRVESITLTQMDQQTSQSQGDPADRKTPPTAPVSPGVKAMSSTGSAGSVIGAGAGAVAAGGKCESSAASIVSSSGPMSPKDISGKSSPGALTSESQSIPTPLGRESHTDTPESSPKPTSPFPRVSKDELKSLEMQHHSQEQMLAGAAAAAGAECEGDIPELHELRGLECTTALSGSTDKIITTTITTVTKVISADGKEIVTEQKTVTTTDSSEPDSEKVVVTTTRTTSESERDQLLPKEVALLRGLYRASTPGSEDDEDLLLGSPRSATSYELQHSSSGVSKRSDLDADGDESQDDIPPQYGSEEHSTARSILLPRTADPMATSFYGALPDSFDVVMKPSTEPIPIQGAPSGDSQSSESVESSSQTWAGHKFLDQADKDFQRALEEHVQARGAEVMSSVTAKYSYSPSKAEEMEQIVSGTAERQRFPLSDVQRARVAESGFATVGSVASQQQQQEKGGEVEQAVPTTTAVTASTTATASSTGALPKDRLEEWGKPLGLPSPAPLPVEGGADIRTTPKKERRLVATKTRLNNEKNLRRRSESPNKAGKKPAPVYVDLTYVPHNGNSYYAHVDFFKRVRARYYVFSG-----TEPSRQVYDALLEAKQTWEDKELEVTIIPTYDTDVLGYWVAENEELLAKHRIDLSPSASRCTINLQDHETSCSAYRLEF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : * :*:: * .* :***.. * :::::* *:****:**:***.:****:*:*** :*::***.:.*****:*:**:*::. .*: *:..::.** : *::* .* ***:: ... . .*. :*.. :. *: *.::.: :* **:.*:**:* * ***:::.* :****:: ::*** ... : : :.:: ::.: *.*: **:** **.* :.*.*:****.:*: ** ******:**:*:::...* *.: .. . . ..:* ::. : ::. .. :. . . . : :* : : . . . * : : :.: .* *. *: :: : :. .. :: ::..: : . . .* : :.: *. :. . :: : : : : : . * *.: . :.: *:: : :. * . : : . . . . : : . . . : : *. : : * . . : . :: . .. : . .*: :*. *:. :. ::. .:: : .: : . *: . .* : . : : . : *:* . : . .* .: .*:. *: :.: . :** ::::.:.. ::::: . :: :* . * .. * * *.:* .. * . . : : .* : : . :: . . .: . .... * .*.. :** * *.* : : . ..:. .: . : .. : . .: . . : . . :. : . :. * * .. . : : . : :. : * :. . . . . . . :. : * . . :. . . . . : :. : : . : . : : . : . : . .. .* . . . . : : . . ::. : : . .. . . : . . . * . : : . : . : . : .. . :. . . : . .: . : . .: . *. : . . . . . * . : . . : : . . . . : : . . : . . . : : : . : . * : : : . . . . : . : . : . . *.*: * .: .. . . :::..*: * . . * * ..** : .*.:.* . .* . :. .. .. . .. * .* * .* * * . *.* : . :: :.::*. . * : .. . : . : :.: . . : .*:****:*:*:: .. .. :**:***: ***.** **** * *****.* * : *:**:***:**:* * :..* . .: : .*:* .: :: * .* ::**", "identical_positions": 220, "similar_positions": 579, "identity": "3.98%" }, { "cls_id": "homologset.agr.MGI:1306778", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P15205-1", "uniprot_id": "MAP1B_RAT", "id": "P15205-1", "name": "Microtubule-associated protein 1B", "aln": "-----------------------------------------------MATVVVEATEPEPSGSIGNPAATTSPSLSHRFLDS---------------------------------KFYLLVVVGETVTEEHLRRAIGNIELGIRSWDTNLIECNLDQELKLFVSRHSARFSPEVPGQKILHHRSDVLETVVLINPSDEAVSTEVRLMITDAARHKLLVLTGQCFENTGELILQSGSFSFQNFIEIFTDQEIGELLSTTHPANKASLTLFCPEEGDWKNSNLDRHNLQDFINIKLNSASILP-EMEGLSEFTEYLSESVEVPSPFDILEPPTSGGFLKLSKPCCYIFPGGRGDSALFAVNGFNMLINGGSERKSCFWKLIRHLDRVDSILLTHIGDDNLPGINSMLQRKIAELEEERSQGSTSNSDWMKNLISPDLGVVFLNVPENLKNPEPNIKMKRSTEEACFTLQYLNKLSMKPEPLFRSVGNAIEPVILFQKMGVGKLEMYVLNPVKSSKEMQYFMQQWTGTNKDKAELILPNGQEVDIPISYLTSVSSLIVWHPANPAEKIIRVLFPGNSTQYNILEGLEKLKHLDFLKQPLATQKDLTGQVSTPPVKQVKLKQRADSR---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ESLKPATKPLSSKSVRKESKEEAPEATKASQVEKTPKVESK--------------------EKVIVKKDKPGKVESKPSVTEKEVPSKEEQSPVKAEVAEKAAT----------------------------------------------------------------------------------------------------------------------------------------------------------------ESKPKVTKDKVVKKEIKTKPEEKKEEK-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PKKEVAKKEDKTPLKKDEKPKKEEAKKEIKKEIKKEEKKE--------------------------------LKKEVKKETPLKDAKKEVKKDEKKEVKKEEKEPKKE---------------------------------------------IKKISKDIKKS-TPLSDTKKPA----ALKPKVAKKEEPTKKEPIAAGKL----------------------------------------------------------------------------KDKGKVKVIKKEGKTTEAAATAVG----TAAVAAAAGVAASGPAKELEAERSLMSSPEDLTK------DFEELKAEEIDVAKDIKPQLELIE------------------------------------DEEKLKETEPGEAYVIQKETEVSKGSAE------------------------------------SPDEGITTTEGEGECEQTPEELEPVEKQGVDDIEKFE----------------------DEGAGFEESSEAGDYEEKAETEEAEEPEEDGEDNVSGSASKHSPTEDEEIAKAEADVHIKEKRESVASGD-------------------DRAEEDMDEALEKGEAEQSEEEGEEEEDKAEDAREEDHEPDKTEAEDYVMAVVDKAAEAGVTEDQYGFLGTPAKQPGVQSPSREPASSIHDETLPGGSESEATASDEENREDQPEEFTATSG---------------------------------------------------------------------------------------------------------------------------------------------------------YTQSTIEISSEPTPMDEMSTPRDVMSDETNN------------------------------------------------------------------------------------------------------EETESPSQEFVNITKYESSLYSQEYSKPVVAS--------------FNGLSDGSKTDATDGRDYNASASTISPPSSMEED-------------------------------------------------------------------------------------------------------------------------------------------------KFSKSALRDAYRPEETDVKTGAELDIKD----VSDERLSPAKSP----------------------------------------------------------------------------------------------------------------------------------------SLSPSPPSPIEKTPLGERSVNFSLTPNEIKASAEGEATAVVSPGVTQAVVEEHCASPEEKTLEVVSPSQSVTGSAGHTPYYQSPTD---EKSSHLPTEVTEKPQAVPVSFEFTEAKDENERSSISPMDEPVP----------------------------------------------------------------------DSESPIEKVLSPLRSPPLIGSESAYEDFLSADDKAL-----------------------------------GRRSESPFEGK------------------NGKQGFSDKESPVSDLTSD-LYQDKQEEKSAGFIPIKEDFSPEKKASDAEIMSSQ------------------------------------------------------------SALALDERKLGGDGSPTQVDVSQFGSFKEDTKMSISEG-----------------------------------------------------------------------------TVSDKSATPVDEG------------------------------------------VAEDTYSHMEGVASVSTASVATSSFPEPTTDDVSPSLHAEVGSPHSTEVDDSLSVSVVQTPTTFQETEMS---------------------------------------------------PSKEECPRPMSISPPDFSPKTAKSRTPVQDHRSEQSSMSIEFG------------------------------QESPEHSLAMDFSRQSPDHPTVGAGMLHITENGPTEVDYSPSDIQDSSLSHKIPPTEEPS-------------------YTQDNDLSELISVSQVEASPSTSSAHTPSQIASPLQEDTLSDVVP-----------------------------------------------PRDMSLYASLASEKVQSLEGEKLSPKSDISPLTPRESSPTYSPGFSDSTSGAKESTAAYQTS---SSPPIDAAAAEPYGFRSSMLFDTMQHHLALSRDLTTS------------------------------------------------------SVEKDNGGKTPG-------------------------------------------------DFNYAYQKPESTTESPDEEDYDYESHEKTIQAHDVGG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YYYEKTERTIKSPCDSGYSYETIEKTTKTPEDGGYSCEITEKTTRTPEEGGYSYEISEKTTRTPEVSG----------------------------------------YTYEKTERSRRLLDDISNG-------------YDDTEDGGHTLGDCSYSYETTEKITSFPESESYSYETT-----------------------------------------------------TKTTRSPDTSAYCYETMEKITKTPQAS------------------------------------------------TYSYETSDRCYTPERKSPSEARQDVDLCLVSSCEFKHPKTELSP-------------SFINPNPLEWFAGEEPTEES----------------------------------------------------------------------------------------------EKPLTQSGGAPPP-----------------------------SGGKQQGRQCDETPPTSVSESAPS---------------------------QTDSDVPPETEECPS-----------------------------------------------------------------ITADANIDSEDESETIPTDKTVTYKHMDPPPAP--MQDRSPSPRHPDVSMVDPEALAIEQNLGKALKKDLKEKAKTKKPGTKTKSSSPVKKGDG-------------------------------------------------------------KSKPSAASPKPGALKESSDKVSR--------------------------------------------------------------------VASPKKKESVEKAMKTTTTPEVKATRGEEKDKETKNAANASASKSVKTATAGPGTTKTAKSSTVPPGLP----------------------------------------------------VYLDLCYIPNHSNSKNVDVEFFKRVRSSYYVVSGNDPAAEEPSRAVLDALLEGKAQWGSN-MQVTLIPTHDSEVMREWYQETHEKQQDLNIMVLASSS--TVVMQDESFPACKIEL--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P14873-1", "uniprot_id": "MAP1B_MOUSE", "id": "P14873-1", "name": "Microtubule-associated protein 1B", "aln": "-----------------------------------------------MATVVVEATEPEPSGSIGNPAASTSPSLSHRFLDS---------------------------------KFYLLVVVGETVTEEHLRRAIGNIELGIRSWDTNLIECNLDQELKLFVSRHSARFSPEVPGQKILHHRSDVLETVVLINPSDEAVSTEVRLMITDAARHKLLVLTGQCFENTGELILQSGSFSFQNFIEIFTDQEIGELLSTTHPANKASLTLFCPEEGDWKNSNLDRHNLQDFINIKLNSASILP-EMEGLSEFTEYLSESVEVPSPFDILEPPTSGGFLKLSKPCCYIFPGGRGDSALFAVNGFNMLINGGSERKSCFWKLIRHLDRVDSILLTHIGDDNLPGINSMLQRKIAELEEERSQGSTSNSDWMKNLISPDLGVVFLNVPENLKDPEPNIKMKRSIEEACFTLQYLNKLSMKPEPLFRSVGNTIEPVILFQKMGVGKLEMYVLNPVKSSKEMQYFMQQWTGTNKDKAELILPNGQEVDIPISYLTSVSSLIVWHPANPAEKIIRVLFPGNSTQYNILEGLEKLKHLDFLKQPLATQKDLTGQVPTPPVKQVKLKQRADSR---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ESLKPATKPVASKSVRKESKEETPEVTKTSQVEKTPKVESK--------------------EKVLVKKDKPVKTESKPSVTEKEVSSKEEQSPVKAEVAEKQAT----------------------------------------------------------------------------------------------------------------------------------------------------------------ESKPKVTKDKVVKKEIKTKLEEKKEEK-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PKKEVVKKEDKTPLKKDEKPRKEEVKKEIKKEIKKEERKE--------------------------------LKKEVKKETPLKDAKKEVKKEEKKEVKKEEKEPKKE---------------------------------------------IKKISKDIKKS-TPLSDTKKPS----ALKPKVAKKEESTKKEPLAAGKL----------------------------------------------------------------------------KDKGKVKVIKKEGKTTEAAATAVGTAATTAAVVAAAGIAASGPVKELEAERSLMSSPEDLTK------DFEELKAEEIDVAKDIKPQLELIE------------------------------------DEEKLKETQPGEAYVIQKETEVSKGSAE------------------------------------SPDEGITTTEGEGECEQTPEELEPVEKQGVDDIEKFE----------------------DEGAGFEESSETGDYEEKAETEEAEEPEEDGEDNASGSASKHSPTEDDESAKAEADVHLKEKRESVVSGD-------------------DRAEEDMDDVLEKGEAEQSEEEGEEE-DKAEDAREEGYEPDKTEAEDYVMAVADKAAEAGVTEEQYGYLGTSAKQPGIQSPSREPASSIHDETLPGGSESEATASDEENREDQPEEFTATSG---------------------------------------------------------------------------------------------------------------------------------------------------------YTQSTIEISSEPTPMDEMSTPRDVMSDETNN------------------------------------------------------------------------------------------------------EETESPSQEFVNITKYESSLYSQEYSKPAVAS--------------FNGLSEGSKTDATDGKDYNASASTISPPSSMEED-------------------------------------------------------------------------------------------------------------------------------------------------KFSKSALRDAYCSEEKELKASAELDIKD----VSDERLSPAKSP----------------------------------------------------------------------------------------------------------------------------------------SLSPSPPSPIEKTPLGERSVNFSLTPNEIKVSAEGEARS-VSPGVTQAVVEEHCASPEEKTLEVVSPSQSVTGSAGHTPYYQSPTD---EKSSHLPTEVTEKPQAVPVSFEFSEAKDENERASLSPMDEPVP----------------------------------------------------------------------DSESPVEKVLSPLRSPPLLGSESPYEDFLSADSKVL-----------------------------------GRRSESPFEGK------------------NGKQGFPDRESPVSDLTSTGLYQDKQEEKSTGFIPIKEDFGPEKKTSDVETMSSQ------------------------------------------------------------SALALDERKLGGDVSPTQIDVSQFGSFKEDTKMSISEG-----------------------------------------------------------------------------TVSDKSATPVDEG------------------------------------------VAEDTYSHMEGVASVSTASVATSSFPEPTTDDVSPSLHAEVGSPHSTEVDDSLSVSVVQTPTTFQETEMS---------------------------------------------------PSKEECPRPMSISPPDFSPKTAKSRTPVQDHRSEQSSMSIEFG------------------------------QESPEHSLAMDFSRQSPDHPTLGASVLHITENGPTEVDYSPSDIQDSSLSHKIPPTEEPS-------------------YTQDNDLSELISVSQVEASPSTSSAHTPSQIASPLQEDTLSDVVP-----------------------------------------------PREMSLYASLASEKVQSLEGEKLSPKSDISPLTPRESSPLYSPGFSDSTSAAKETAAAHQAS---SSPPIDAATAEPYGFRSSMLFDTMQHHLALNRDLTTS------------------------------------------------------SVEKDSGGKTPG-------------------------------------------------DFNYAYQKPENAAGSPDEEDYDYESQEKTIRTHDVGG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YYYEKTERTIKSPCDSGYSYETIEKTIKTPEDGGYTCEITEKTTRTPEEGGYSYEISEKTTRTPEVSG----------------------------------------YTYEKTERSRRLLDDISNG-------------YDDTEDGGHTLGDCSYSYETTEKITSFPESESYSYETS-----------------------------------------------------TKTTRSPDTSAYCYETMEKITKTPQAS------------------------------------------------TYSYETSDRCYTTEKKSPSEARQDVDLCLVSSCEFKHPKTELSP-------------SFINPNPLEWFAGEEPTEES----------------------------------------------------------------------------------------------EKPLTQSGGAPPP-----------------------------SGGKQQGRQCDETPPTSVSESAPS---------------------------QTDSDVPPETEECPS-----------------------------------------------------------------ITADANIDSEDESETIPTDKTVTYKHMDPPPAP--MQDRSPSPRHPDVSMVDPDALAVDQNLGKALKKDLKEKTKTKKPGTKTKSSSPVKKGDG-------------------------------------------------------------KSKPLAASPKPGALKESSDKVSR--------------------------------------------------------------------VASPKKKESVEKATKTTTTPEVKATRGEEKDKETKNAANASASKSAKTATAGPGTTKTAKSSTVPPGLP----------------------------------------------------VYLDLCYIPNHSNSKNVDVEFFKRVRSSYYVVSGNDPAAEEPSRAVLDALLEGKAQWGSN-MQVTLIPTHDSEVMREWYQETHEKQQDLNIMVLASSS--TVVMQDESFPACKIEL--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P46821-1", "uniprot_id": "MAP1B_HUMAN", "id": "P46821-1", "name": "Microtubule-associated protein 1B", "aln": "-----------------------------------------------MATVVVEATEPEPSGSIANPAASTSPSLSHRFLDS---------------------------------KFYLLVVVGEIVTEEHLRRAIGNIELGIRSWDTNLIECNLDQELKLFVSRHSARFSPEVPGQKILHHRSDVLETVVLINPSDEAVSTEVRLMITDAARHKLLVLTGQCFENTGELILQSGSFSFQNFIEIFTDQEIGELLSTTHPANKASLTLFCPEEGDWKNSNLDRHNLQDFINIKLNSASILP-EMEGLSEFTEYLSESVEVPSPFDILEPPTSGGFLKLSKPCCYIFPGGRGDSALFAVNGFNMLINGGSERKSCFWKLIRHLDRVDSILLTHIGDDNLPGINSMLQRKIAELEEEQSQGSTTNSDWMKNLISPDLGVVFLNVPENLKNPEPNIKMKRSIEEACFTLQYLNKLSMKPEPLFRSVGNTIDPVILFQKMGVGKLEMYVLNPVKSSKEMQYFMQQWTGTNKDKAEFILPNGQEVDLPISYLTSVSSLIVWHPANPAEKIIRVLFPGNSTQYNILEGLEKLKHLDFLKQPLATQKDLTGQVPTPVVKQTKLKQRADSR---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ESLKPAAKPLPSKSVRKESKEETPEVTKVNHVEKPPKVESK--------------------EKVMVKKDKPIKTETKPSVTEKEVPSKEEPSPVKAEVAEKQAT----------------------------------------------------------------------------------------------------------------------------------------------------------------DVKPKAAKEKTVKKETKVKPEDKKEEKE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKEIKKEEKKE--------------------------------PKKEVKKETPPKEVKKEVKKEEKKEVKKEEKEPKKE---------------------------------------------IKKLPKDAKKSSTPLSEAKKPA----ALKPKVPKKEESVKKDSVAAGKP----------------------------------------------------------------------------KEKGKIKVIKKEGKAAEAVAAAVGTGATTAAVMAAAGIAAIGPAKELEAERSLMSSPEDLTK------DFEELKAEEVDVTKDIKPQLELIE------------------------------------DEEKLKETEPVEAYVIQKEREVTKGPAE------------------------------------SPDEGITTTEGEGECEQTPEELEPVEKQGVDDIEKFE----------------------DEGAGFEESSETGDYEEKAETEEAEEPEEDGEEHVCVSASKHSPTEDEESAKAEADAYIREKRESVASGD-------------------DRAEEDMDEAIEKGEAEQSEEEADEE-DKAEDAREEEYEPEKMEAEDYVMAVVDKAAEAGGAEEQYGFLTTPTKQLGAQSPGREPASSIHDETLPGGSESEATASDEENREDQPEEFTATSG---------------------------------------------------------------------------------------------------------------------------------------------------------YTQSTIEISSEPTPMDEMSTPRDVMSDETNN------------------------------------------------------------------------------------------------------EETESPSQEFVNITKYESSLYSQEYSKPADVTP-------------LNGFSEGSKTDATDGKDYNASASTISPPSSMEED-------------------------------------------------------------------------------------------------------------------------------------------------KFSRSALRDAYCS---EVKASTTLDIKDSISAVSSEKVSPSKSP----------------------------------------------------------------------------------------------------------------------------------------SLSPSPPSPLEKTPLGERSVNFSLTPNEIKVSAEAEVAP-VSPEVTQEVVEEHCASPEDKTLEVVSPSQSVTGSAGHTPYYQSPTD---EKSSHLPTEVIEKPPAVPVSFEFSDAKDENERASVSPMDEPVP----------------------------------------------------------------------DSESPIEKVLSPLRSPPLIGSESAYESFLSADDKAS-----------------------------------GRGAESPFEEK------------------SGKQGSPDQVSPVSEMTSTSLYQDKQEGKSTDFAPIKEDFGQEKKTDDVEAMSSQ------------------------------------------------------------PALALDERKLG-DVSPTQIDVSQFGSFKEDTKMSISEG-----------------------------------------------------------------------------TVSDKSATPVDEG------------------------------------------VAEDTYSHMEGVASVSTASVATSSFPEPTTDDVSPSLHAEVGSPHSTEVDDSLSVSVVQTPTTFQETEMS---------------------------------------------------PSKEECPRPMSISPPDFSPKTAKSRTPVQDHRSEQSSMSIEFG------------------------------QESPEQSLAMDFSRQSPDHPTVGAGVLHITENGPTEVDYSPSDMQDSSLSHKIPPMEEPS-------------------YTQDNDLSELISVSQVEASPSTSSAHTPSQIASPLQEDTLSDVAP-----------------------------------------------PRDMSLYASLTSEKVQSLEGEKLSPKSDISPLTPRESSPLYSPTFSDSTSAVKEKTATCHSS---SSPPIDAASAEPYGFRASVLFDTMQHHLALNRDLSTP------------------------------------------------------GLEKDSGGKTPG-------------------------------------------------DFSYAYQKPEETTRSPDEEDYDYESYEKTTRTSDVGG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YYYEKIERTTKSPSDSGYSYETIGKTTKTPEDGDYSYEIIEKTTRTPEEGGYSYDISEKTTSPPEVSG----------------------------------------YSYEKTERSRRLLDDISNG-------------YDDSEDGGHTLGDPSYSYETTEKITSFPESEGYSYETS-----------------------------------------------------TKTTRTPDTSTYCYETAEKITRTPQAS------------------------------------------------TYSYETSDLCYTAEKKSPSEARQDVDLCLVSSCEYKHPKTELSP-------------SFINPNPLEWFASEEPTEES----------------------------------------------------------------------------------------------EKPLTQSGGAPPP-----------------------------PGGKQQGRQCDETPPTSVSESAPS---------------------------QTDSDVPPETEECPS-----------------------------------------------------------------ITADANIDSEDESETIPTDKTVTYKHMDPPPAP--VQDRSPSPRHPDVSMVDPEALAIEQNLGKALKKDLKEKTKTKKPGTKTKSSSPVKKSDG-------------------------------------------------------------KSKPLAASPKPAGLKESSDKVSR--------------------------------------------------------------------VASPKKKESVEKAAKPTTTPEVKAARGEEKDKETKNAANASASKSAKTATAGPGTTKTTKSSAVPPGLP----------------------------------------------------VYLDLCYIPNHSNSKNVDVEFFKRVRSSYYVVSGNDPAAEEPSRAVLDALLEGKAQWGSN-MQVTLIPTHDSEVMREWYQETHEKQQDLNIMVLASSS--TVVMQDESFPACKIEL--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W596-1", "uniprot_id": "FUTSC_DROME", "id": "Q9W596-1", "name": "Microtubule-associated protein futsch", "aln": "MGDQPKATTTATGGAAGPVPEGDAVMATTNQDALAKGAGDGPAQDAAQEPGQAEHGEPGDGGDGGDDGATDAGASSLPPSEIGGRAPLDTACSDADGGAPSSLAGGIVGPPSPLTGCYLLIVLGEPHSEEHKDNILQHLLKGFLSWDVSDCHVDLEEELN-TITQHAPEGEEARHGERLIQYASENLVTEVLIHPQYNTLIQCMRNLLSSFTRHRHIIHAGYTFSGNGSWILQDGTFSVADFSEAFQEHDVQRVIR--AYADTITMNIHCADAGLWHT--LPEKAFARQCRIRINPVDVLDTSSECINGFIDYLAPMVMPTSLRELLETSDVVGNIRFTHPTLYVFPGGQGDAALFGINGFNMLVDGGFNRKACFWDFARHLDRLDAVLMTRLNNSNVQGLGAVVSRKRDAHVYPQIGHFFGNVPDRKGLPSPDG------------DKDRDPLLIDLFERGHGIVSDLKALDLKPQCCYRNQ----EPVNLYHKVGHGTLDMYVISPARDSKEVKEFLQKWHAG--DQRLFAARDSRDFNFPLQNLVSICALLVWQPANPDDTITRILFPGSTPDFKIQEGLEKLKHLEFMKHSTCTAKSIAPAIQTVTSTRKSLKSAIEATPAPPSASYKTTKFSPVASAALAVQHPQQQDNKAKEAAAAAAAAAAAAASAATIARAKADSMDTDAEPEHEADPEPADTGDEAAPTEQEPEAETEPEPEHEPEAEQDKDVGEEKKVEVLIMKPQQATPAVIAASGKDGVDAASADATPTGKLSKASAKGKADKPRAEVKPVVRSRIDTKPPKSMDRKLAKRDEKKSSPTTTPAARAPVAQNAKPKVLSRPATKSSPSSTPAKSAKEANNRKVLESKQQAARVQATSTVSRRVTSTASERRVQQQAEAKTAATGATQATQRKPISRRPRGVSPSKRAPAPGSPVKQAKPKAADLKKTRLDKGGTTDSSLVSTPSADEATAAKKLQDLTASQELDAEKQRELDDLKEEQEVVREIEAVFSRDEMKRQQHQQIKAELREMPAEGTGDGENEPDEEEEYLIIEKEEVEQYTEDSIVEQESSMTKEEEIQKHQRDSQESEKKRKKSAEEEIEAAIAKVEAAERKARLEGASARQDESELDVEPEQSKIKAEVQDIIATAKDIAKSRTEEQLAKPAEEELSSPTPEEKLSKKTSDTKDDQIGAPVDVLPVNLQESLPEEKFSATIESGATTAPTLPEDERIPLDQIKEDLVIEEKYVKEETKEAEAIVVATVQTLPEAAPLAIDTILASATKDAPKDANAEALGELPDSGERVLPMKMTFEAQQNLLRDVIKTPDEVADLPVHEEADLGLYEKDSQDAGAKSISHKEESAKEEKETDDEKENKVGEIELGDEPNKVDISHVLLKESVQEVAEKVVVIETTVEKKQEEIVEATTVITQENQEDLMEQVKDKEEHEQKIESGIITEKEAKKSASTPEEKETSDITSDDELPAQLADPTTVPPKSAKDREDTGSIESPPTIEEAIEVEVQAKQEAQKPVPAPEEAIKTEKSPLASKETSRPESATGSVKEDTEQTKSKKSPVPSRPESEAKDKKSPFASGEASRPESVAESVKDEAGKAESRRESIAKTHKDESSLDKAKEQESRRESLAESIKPESGIDEKSALASKEASRPESVTDKSKEPSRRESIAESLKAESTKDEKSAPPSKEASRPGSVVESVKDETEKSKEPSRRESIAESAKPPIEFREVSRPESVIDGIKDESAKPESRRDSPLASKEASRPESVLESVKDEPIKSTEKSRRESVAESFKADSTKDEKSPLTSKDISRPESAVENVMDAVGSAERSQPESVTASRDVSRPESVAESEKDDTDKPESVVESVIPASDVVEIEKGAADKEKGVFVSLEIGKPDSPSEVISRPGPVVESVKPESRRESSTEIVLPCHAEDSKEPSRPESKVECLKDESEVLKGSTRRESVAESDKSSQPFKETSRPESAVGSMKDESMSKEPSRRESVKDGAAQSRETSRPASVAESAKDGADDLKELSRPESTTQSKEAGSIKDEKSPLASEEASRPASVAESVKDEAEKSKEESRRESVAEKSPLPSKEASRPASVAESIKDEAEKSKEESRRESVAEKSPLPSKEASRPASVAESIKDEAEKSKEESRRESVAEKSPLPSKEASRPASVAESIKDEAEKSKEESRRESVAEKSPLPSKEASRPASVAESIKDEAEKSKEESRRESVAEKSPLPSKEASRPASVAESIKDEAEKSKEESRRESVAEKSPLPSKEASRPASVAESIKDEAEKSKEESRRESVAEKSPLPSKEASRPASVAESIKDEAEKSKEETRRESVAEKSPLPSKEASRPASVAESIKDEAEKSKEESRRESAAEKSPLPSKEASRPASVAESVKDEADKSKEESRRESMAESGKAQSIKGDQSPLKEVSRPESVAESVKDDPVKSKEPSRRESVAGSVTADSARDDQSPLESKGASRPESVVDSVKDEAEKQESRRESKTESVIPPKAKDDKSPKEVLQPVSMTETIREDADQPMKPSQAESRRESIAESIKASSPRDEKSPLASKEASRPGSVAESIKYDLDKPQIIKDDKSTEHSRRESLEDKSAVTSEKSVSRPLSVASDHEAAVAIEDDAKSSISPKDKSRPGFVAETVSSPIEEATMEFSKIEVVEKSSLALSLQGGSGGKLQTDSSPVDVAEGDFSHAVASVSTVTPTLTKPAELAQIGAAKTVSSPLDEALRTPSAPEHISRADSPAECASEEIASQDKSPQVLKESSRPAWVAESKDDAAQLKSSVEDLRSPVASTEISRPASAGETASSPIEEAPKDFAEFEQAEKAVLPLTIELKGNLPTLSSPVDVAHGDFPQTSTPTSSPTVASVQPAELSKVDIEKTASSPIDEAPKSLIGCPAEERPESPAESAKDAAESVEKSKDASRPPSVVESTKADSTKGDISPSPESVLEGPKDDVEKSKESSRPPSVSASITGDSTKDVSRPASVVESVKDEHDKAESRRESIAKVESVIDEAGKSDSKSSSQDSQKDEKSTLASKEASRRESVVESSKDDAEKSESRPESVIASGEPVPRESKSPLDSKDTSRPGSMVESVTAEDEKSEQQSRRESVAESVKADTKKDGKSQEASRPSSVDELLKDDDEKQESRRQSITGSHKAMSTMGDESPMDKADKSKEPSRPESVAESIKHENTKDEESPLGSRRDSVAESIKSDITKGEKSPLPSKEVSRPESVVGSIKDEKAESRRESVAESVKPESSKDATSAPPSKEHSRPESVLGSLKDEGDKTTSRRVSVADSIKDEKSLLVSQEASRPESEAESLKDAAAPSQETSRPESVTESVKDGKSPVASKEASRPASVAENAKDSADESKEQRPESLPQSKAGSIKDEKSPLASKDEAEKSKEESRRESVAEQFPLVSKEVSRPASVAESVKDEAEKSKEESPLMSKEASRPASVAGSVKDEAEKSKEESRRESVAEKSPLPSKEASRPASVAESVKDEADKSKEESRRESGAEKSPLASKEASRPASVAESIKDEAEKSKEESRRESVAEKSPLPSKEASRPTSVAESVKDEAEKSKEESRRDSVAEKSPLASKEASRPASVAESVQDEAEKSKEESRRESVAEKSPLASKEASRPASVAESIKDEAEKSKEESRRESVAEKSPLASKEASRPTSVAESVKDEAEKSKEESSRDSVAEKSPLASKEASRPASVAESVQDEAEKSKEESRRESVAEKSPLASKEASRPASVAESVKDDAEKSKEESRRESVAEKSPLASKEASRPASVAESVKDEAEKSKEESRRESVAEKSPLPSKEASRPTSVAESVKDEAEKSKEESRRESVAEKSSLASKKASRPASVAESVKDEAEKSKEESRRESVAEKSPLASKEASRPASVAESVKDEAEKSKEESRRESVAEKSPLPSKEASRPTSVAESVKDEADKSKEESRRESGAEKSPLASMEASRPTSVAESVKDETEKSKEESRRESVTEKSPLPSKEASRPTSVAESVKDEAEKSKEESRRESVAEKSPLASKESSRPASVAESIKDEAEGTKQESRRESMPESGKAESIKGDQSSLASKETSRPDSVVESVKDETEKPEGSAIDKSQVASRPESVAVSAKDEKSPLHSRPESVADKSPDASKEASRSLSVAETASSPIEEGPRSIADLSLPLNLTGEAKGKLPTLSSPIDVAEGDFLEVKAESSPRPAVLSKPAEFSQPDTGHTASTPVDEASPVLEEIEVVEQHTTSGVGATGATAETDLLDLTETKSETVTKQSETTLFETLTSKVESKVEVLESSVKQVEEKVQTSVKQAETTVTDSLEQLTKKSSEQLTEIKSVLDTNFEEVAKIVADVAKVLKSDKDITDIIPDFDERQLEEKLKSTADTEEESDKSTRDEKSLEISVKVEIESEKSSPDQKSGPISIEEKDKIEQSEKAQLRQGILTSSRPESVASQPESVPSPSQSAASHEHKEVELSESHKAEKSSRPESVASQVSEKDMKTSRPASSTSQFSTKEGDEETTESLLHSLTTTETVETKQMEEKSSFESVSTSVTKSTVLSSQSTVQLREESTSESLSSSLKVEDSSRRESLSSLLAEKGGIATNTSLKEDTSASASQLEELLVQSEECSSESIVSEIQTSIAQKSNKEIKDARETKVTSQFTTTTSSATKDDSLKETVAEFLATEKIVSAKEAFSTEATKSADDCLKKTTASAVSSTSASQRALFVGTDESRRESLLSQASESRLTHSDPEDEEPADDVDERSSVKESRSKSIATIMMTSIYKPSEDMEPISKLVEEEHEHVEELAQEVTSTSKTTTLLQSSEQSSTTTSSTSKTGASRVESITLTQMDQQTSQSQGDPADRKTPPTAPVSPGVKAMSSTGSAGSVIGAGAGAVAAGGKCESSAASIVSSSGPMSPKDISGKSSPGALTSESQSIPTPLGRESHTDTPESSPKPTSPFPRVSKDELKSLEMQHHSQEQMLAGAAAAAGAECEGDIPELHELRGLECTTALSGSTDKIITTTITTVTKVISADGKEIVTEQKTVTTTDSSEPDSEKVVVTTTRTTSESERDQLLPKEVALLRGLYRASTPGSEDDEDLLLGSPRSATSYELQHSSSGVSKRSDLDADGDESQDDIPPQYGSEEHSTARSILLPRTADPMATSFYGALPDSFDVVMKPSTEPIPIQGAPSGDSQSSESVESSSQTWAGHKFLDQADKDFQRALEEHVQARGAEVMSSVTAKYSYSPSKAEEMEQIVSGTAERQRFPLSDVQRARVAESGFATVGSVASQQQQQEKGGEVEQAVPTTTAVTASTTATASSTGALPKDRLEEWGKPLGLPSPAPLPVEGGADIRTTPKKERRLVATKTRLNNEKNLRRRSESPNKAGKKPAPVYVDLTYVPHNGNSYYAHVDFFKRVRARYYVFSG-----TEPSRQVYDALLEAKQTWEDKELEVTIIPTYDTDVLGYWVAENEELLAKHRIDLSPSASRCTINLQDHETSCSAYRLEF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .* ** .*. .: .*: : : * : ***:*:** :*** . : :: *: ***.. . :*::**: :::*:.. . *:::::: *: * * ***:*. ::: :* :::. :**: :: :* *...*. ***.*:**. :* * * :::: .:: *:. ::.:.*.: * *:. * .: : .*::*...:* . * :. * :**: * .* ::**.. * :::::* *:****:**:***.:******::** :**:***.: *****:*::*:*::.:.*: *:.:::.** : * *.* *** : : : : *.. :. *: *.:**: :*. :** *::*:* *.*:***:.*.:.***:: *:*:* . *: : :.::.::*:. *.*:.:*:**:**** :.* *:****.:.:::* *********:*:*:. .* *.:: : * .: .**. :: :. *. : :..:. :*.* :* . : *** *: .**: .*::. :.::..:*:.: ..: .* : *:. ** : :.. :*:: ::*. : . *.:*:.* * * . * :*:*: ..*..: *... .:*:: :: : *: *.*. * . :: :.:*:*.. * :*:*.::* :* ... :** .* .::.:*. ::* :. *.:*. :::.:* . *. . * *.: .:.* . *** : . .:*. . * . *:*:. ..**.:.: *. *:: * *.: .**: : ::.* . :. ::.* ** **.:. * *.:. .:.. . * .: *:*.**::::. .* *. * . :* :::* .. *. .*. * . *:. * * **: .*.*.. .: . *.**:. :: .:. **:* ..* *. *.. *.:* : *. :*.:*:. .. .: . : . *: . :* .. .*: ::: ..*:. .** *. :*:.*: . * : .: .*..: :*:.*:* *..* .. .:: .*: : * : . . :*.* *:* *:* .: : :: *: :: :.:. :* .::* * *: .* :. :.: * *: . : : .::* *:. .:* . *. .:**** * :* . . .. : * * .:..* .: ** .: :. . :. * :: :** ..**:: .*. * ::.* *.:: .: :* * : *.*.. *: . .**** ..** :.: .. :: . :*.**. :. .:.. : :**: * . ::. .: .* *. : .*:. :. .. :* . :..: .. .* . * *. . . : * .: *: **:*::.. *:. :*::**. * .*. ***. .. * . * . .:.. * *:.: *: ** . .: : .:. . * :.: ..* * ****. * . . ::.* *. *.* : .:::. * * . ::* *.* ..:.:** .. .: ::*. :.: * .: : .*::.* * .: : :: :.::* .:.. *** .** *.: .: *. :*:: : .. .* *: *: .* :* * .: .. :: ***..:*:* * * . .. *.. : : * .** . ::.* .. *: :* : : *: * .::.: *.. * . . .:**..: *..:*. .* :: . .. : .: *.. **..*: . :. : *: * . **:: :.* * : .:* . :.. :. **:.*.. : .::*: :. .*.. .* . :* ***.: : .* *:*: *:*: . ***: . : * :.:: :.* . .: ::: :.:. .:** :..* ** .: ..*. * *::. . . :: .:* :*. :: :** * *. .*. * :*:.:..: **.*.* ::.:*.* .: : .* **: ::: * * .* :. :**** .. . * : : : :. ..: . : *. :*: :.* :* . . ::. . ..:: :* :::... .::* . . *.. .:**:.*. * .: ** : ..:: : : :* * :: . .:: .:**.:..::::*. ... :. * *** **:** *:*::.** ..*:******: ***.** **** * *****.* * .: ::**:***:*::*: * *..* . .* : .*:* *: :**.. ... .* ", "identical_positions": 570, "similar_positions": 1023, "identity": "10.32%" }, { "cls_id": "homologset.agr.MGI:1306779", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88430-1", "uniprot_id": "CCL22_MOUSE", "id": "O88430-1", "name": "C-C motif chemokine 22", "aln": "MATLRVPLLVALVLLAVAIQTSDAGPYGANVEDSICCQDYIRHPLPSRLVKEFFWTSKSCRKPGVVLITVKNRDICADPRQVWVKKLLHKLS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00626-1", "uniprot_id": "CCL22_HUMAN", "id": "O00626-1", "name": "C-C motif chemokine 22", "aln": "MDRLQTALLVVLVLLAVALQATEAGPYGANMEDSVCCRDYVRYRLPLRVVKHFYWTSDSCPRPGVVLLTFRDKEICADPRVPWVKMILNKLSQ", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* *:..***.*******:*:::*******:***:**:**:*: ** *:**.*:***.** :*****:*.::::****** *** :*:*** ", "identical_positions": 58, "similar_positions": 26, "identity": "62.37%" }, { "cls_id": "homologset.agr.MGI:1306780", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q06889-1", "uniprot_id": "EGR3_HUMAN", "id": "Q06889-1", "name": "Early growth response protein 3", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTGKLAEKLPVTMSS--------------------------------LLNQLPDNLYP-----------------------------EEIPSALNLFSGSSDSVVHYNQMATENVMDIGLTNEKP-----------------NPELSYSGSFQPAPGNKTVTYLGKFAFDSPSNWCQDN------------------------------------------------------------------------------------------------------------------------------------IISLMSAGILGVPPASGALSTQTS--------------------------------------TASMVQPPQGDVEAMYPALPPYSNCGDLYSEPVSFHDPQGNPGLAYSPQDYQSAKPALDSNLFPMIPDYN------------------------------LYHHPNDMGSIPEHKPFQGMDPIRVNPPPITPLETIKAFKDKQIHPGFGSLPQP--------------------------------------------------------------------------PLTLKPIRPRKYPNRPSKTPLHERPHACPAEGCDRRFSRSDELTRHLRIHTGHKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFACEFCGRKFARSDERKRHAKIHLKQKEKKAEKGG------------------------------------------------------------------------------APSASSAPPVSLAPVVTTCA---------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P43301-1", "uniprot_id": "EGR3_RAT", "id": "P43301-1", "name": "Early growth response protein 3", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTGKLAEKLPVTMSS--------------------------------LLNQLPDNLYP-----------------------------EEIPSALNLFSGSSDSVAHYTQMATENVMDIGLTNEKP-----------------NPELSYSGSFQPAPGNKTVTYLGKFAFDSPSNWCQDN------------------------------------------------------------------------------------------------------------------------------------IISLMSAGILGVPPASGALSTQTT--------------------------------------TASMVQPPQGDVEAMYPALPPYSNCGDLYSEPVSFHDPQGNPGLAYSPQDYQSAKPALDSNLFPMIPDYN------------------------------LYHHPNDMGSIPEHKPFQGMDPIRVNPPPITPLETIKAFKDKQIHPGFGSLPQP--------------------------------------------------------------------------PLTLKPIRPRKYPNRPSKTPLHERPHACPAEGCDRRFSRSDELTRHLRIHTGHKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFACEFCGRKFARSDERKRHAKIHLKQKEKKSEKGG------------------------------------------------------------------------------APSASSAPTVSLAPVVTTCA---------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P43300-1", "uniprot_id": "EGR3_MOUSE", "id": "P43300-1", "name": "Early growth response protein 3", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTGKLAEKLPVTMSS--------------------------------LLNQLPDNLYP-----------------------------EEIPSALNLFSGSSDSVAHYNQMATENVMDIGLTNEKP-----------------NPELSYSSSFQPAPGNKTVTYLGKFAFDSPSNWCQDN------------------------------------------------------------------------------------------------------------------------------------IISLMSAGILGVPPASGALSTQTS--------------------------------------TASMVQPPQGDVEAMYPALPPYSNCGDLYSEPVSFHDPQGNPGLAYSPQDYQSAKPALDSNLFPMIPDYN------------------------------LYHHPNDMGSIPEHKPFQGMDPIRVNPPPITPLETIKAFKDKQIHPGFGSLPQP--------------------------------------------------------------------------PLTLKPIRPRKYPNRPSKTPLHERPHACPAEGCDRRFSRSDELTRHLRIHTGHKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFACEFCGRKFARSDERKRHAKIHLKQKEKKSEKGG------------------------------------------------------------------------------APSASSAPTVSLAPVVTTCA---------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0B4KGW2-1", "uniprot_id": "A0A0B4KGW2_DROME", "id": "A0A0B4KGW2-1", "name": "", "aln": "MLLTMRRQNELIVGSQQHPSATSSASSSAGATSSPGLSGQNLNLVAGAGAATNSTSANSQDSLNTPTTPLLGLSRNPLQFAPPPAPPIAVPNPAASGPTFGYYQTVNAAPPIHHSPAATSEVSTAPQPPVELDEYVDILQVQQLLLDSSAAAAAAANNPPTTEQSVQQPQQNTVVQPHPHQQQQQQQQQQQPQQQQQQPQQILAKPRPRINLQKATEYAAQLAQAESSSPGSRRVLLDYPSPYLYGNPYHHHTPPGEDLVALWFGSNGTGGVAPGTPSAAMIMEGLETLVAPTHHAFLLTETAAAAHFNVLSFDTCLFKTSTAAQSSGSPSTATYLSPAQFGGSHHGGASTSSNSLNSSSTASSSSTSSSLLHYTTASAAAAAAAAAAASANNSVLRARNQTATPTQGGSPGHVAVQPSATASSGRSSASHLSLLNTSGQHSPTSSAVEQVEAHKQLIEALPGDLNTPVTTSSDIPSFFGPTTVVEPPPITGSIESEDLSLEPQVISVASPVLSHCSPLKEERSTPPALAIVKEESSNNSCNMYPQHNNNNNNNNNTTSSSTTTTSKQTTSESNTECVGSPGNHTQSHQQQQQQLQHNNTSSSNSNCHHSHQQQQQQQQQQHMSSPQQQYQQHQILHQQQQLPNHHHHHHHHHHHHSQLQQLQQQQQQQQQQQQHQQQPLHQQQQLQHQQQQQHHQQHYQQHAIQHQQSQQQASKISYRGIFTTTGNAMNAAAAAAAAAAQQQHQQQQQHQQQLPSPQLGVLAGPMSPPSNSLGNSWGLPSPDKTMFQPPLFSLPAHYATMQQQQQQQQQQQQQQQQQQAAGAAPSPYDDGRAAAAAAAQHAELLGLTMDCTPLLLKQPPPSYAGASAGFPGLGDLHSSHEQQLQQQQYVRSQPKYQWLDSPADYAQQQQQVQQVQQQQQQQQTLVLPGPTSSASSSNAALGVLIPKQENYPDMQPSSNGTGYSGGSGGSSAAAAAAAAAAAAAVQLAEYSPSTSKGHEILSQVYQQSTVPLKLVPVKPRKYPNRPSKTPVHERPYACPVENCDRRFSRSDELTRHIRIHTGQKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFSCDICGRKFARSDEKKRHAKVHLKQRIKKEKVRGEQQQQQQQQQQQQQQQQQQQLQQQQEQHHLSLQQHQQYQQHHLLHSADLAIVTSSASMXRLENSASSVDQAQTPTPTPAPAATQKVSLALALDLDESAFPFELTSDYGTLSPLTSPRQFNYVWVGQDSSQPFFYKDNVSVQEK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .*::* : ..* ** *:: **.:* . *::. :::* :* : * . : *. .*: * * : . :.* .:..::*.: .. ...**.* *.: *:: . .: ....*:.* : * :*.*** .: * *.:: .: : .: . ::. * . .*. :* .* .::*: : * . :: : : * *::: ::. : : :: : ::. : ** * ... **.* *::************:****:***.*.**************:*****:*******************************:*::**********:*****:****: ** : * **:*:. .::** : .* ", "identical_positions": 147, "similar_positions": 129, "identity": "11.57%" }, { "cls_id": "homologset.agr.MGI:1306782", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P49897-1", "uniprot_id": "IOD3_RAT", "id": "P49897-1", "name": "Thyroxine 5-deiodinase", "aln": "MPRQAASRLVVGEGEGPPGASGPAATMLRSLLLHSLRLCAQTASCLVLFPRFLGTAFMLWLLDFLCIRKHFLRRRHPDHPEPEVELNSEGEEMPPDDPPICVSDDNRLCTLASLKAVWHGQKLDFFKQAHEGGPAPNSEVVRPDGFQSQRILDYAQGTRPLVLNFGSCTUPPFMARMSAFQRLVTKYQRDVDFLIIYIEEAHPSDGWVTTDSPYVIPQHRSLEDRVSAARVLQQGAPGCALVLDTMANSSSSAYGAYFERLYVIQSGTIMYQGGRGPDGYQVSELRTWLERYDEQLHGTRPRRL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91ZI8-1", "uniprot_id": "IOD3_MOUSE", "id": "Q91ZI8-1", "name": "Thyroxine 5-deiodinase", "aln": "MPRQAASRLVVGEGEGPPGASGPAATMLRSLLLHSLRLCAQTASCLVLFPRFLGTAFMLWLLDFLCIRKHFLRRRHPDHPEPEVELNSEGEEMPPDDPPICVSDDNRLCTLASLKAVWHGQKLDFFKQAHEGGPAPNSEVVRPDGFQSQRILDYAQGTRPLVLNFGSCTUPPFMARMSAFQRLVTKYQRDVDFLIIYIEEAHPSDGWVTTDSPYVIPQHRSLEDRVSAARVLQQGAPGCALVLDTMANSSSSAYGAYFERLYVIQSGTIMYQGGRGPDGYQVSELRTWLERYDEQLHGTRPHRF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P55073-1", "uniprot_id": "IOD3_HUMAN", "id": "P55073-1", "name": "Thyroxine 5-deiodinase", "aln": "MPRQATSRLVVGEGEGSQGASGPAATMLRSLLLHSLRLCAQTASCLVLFPRFLGTAFMLWLLDFLCIRKHFLGRRRRGQPEPEVELNSEGEEVPPDDPPICVSDDNRLCTLASLKAVWHGQKLDFFKQAHEGGPAPNSEVVLPDGFQSQHILDYAQGNRPLVLNFGSCTUPPFMARMSAFQRLVTKYQRDVDFLIIYIEEAHPSDGWVTTDSPYIIPQHRSLEDRVSAARVLQQGAPGCALVLDTMANSSSSAYGAYFERLYVIQSGTIMYQGGRGPDGYQVSELRTWLERYDEQLHGARPRRV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1P485-1", "uniprot_id": "A0A8M1P485_DANRE", "id": "A0A8M1P485-1", "name": "Iodothyronine deiodinase", "aln": "--------------------------------MNTGRALKNALVCLLILPRFLVAAFMLWCLDFLCVRKRVLVHLQERAEE-------EEEDAEEEEEPLCISDSSRMFSWESLKAVFHGHKLDYMKSARLGHAAPDSEVFPLAEPRRGRVLEFARGHRPLVLSFGSCSUPPFMRRLKAFRRLVLRYADVADALLIYIEEAHPSDGWRSSDAPHQIRRHRSLEERLSAARLMEREAPGCAVVADGMENAANSAYGAYFDRLYIVQDGRVVYQGGRGPEGFRISELRHWLDRYRERLRDAVIPV-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::: * :: **:::**** :***** *****:**:.* : : * * *: :: *:*:**..*: : *****:**:***::*.*: * .**:***. : ::*::*:* *****.****:***** *:.**:*** :* .* *:************ ::*:*: * :*****:*:****:::: *****:* * * *::.*******:***::*.* ::*******:*:::**** **:** *:*:.: ", "identical_positions": 136, "similar_positions": 76, "identity": "44.74%" }, { "cls_id": "homologset.agr.MGI:1306784", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35740-1", "uniprot_id": "CITE2_MOUSE", "id": "O35740-1", "name": "Cbp/p300-interacting transactivator 2", "aln": "MADHMMAMNHGRFPDGTNGLHHHPAHRMGMGQFPSPHHHQQQQPQHAFNALMGEHIHYGAGNMNATSGIRHAMGPGTVNGGHPPSALAPAARFNNSQFMGPPVASQGGSLPASMQLQKLNNQYFNHHPYPHNHYMPDLHPTAGHQMNGTNQHFRDCNPKHSGGSSTPGGAGGSGTPGGSGGTSGGAGGSSAGGSGGGS-TMPASVAHVPAAMLPPNVIDTDFIDEEVLMSLVIEMGLDRIKELPELWLGQNEFDFMTDFVCKQQPSRVSC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99MA1-1", "uniprot_id": "Q99MA1_RAT", "id": "Q99MA1-1", "name": "Cbp/p300-interacting transactivator 2", "aln": "MADHMMAMNHGRFPDGTNGLHHHPAHRMGMGQFPSPHHHQQQQPQHAFNALMGEHIHYGAGNMNATSGIRHAMGPGTVNGGHPPSALAPAARFNNSQFMGPPVASQGGSLPASMQLQKLNNQYFNHHPYPHNHYMPDLHPAAGHQMNGTNQHFRDCNPKHSGGSSTPGGAGGSGTPGGSGGTSGGAGGSSAGGSGGGS-TMPASVAHVPAAMLPPNVIDTDFIDEEVLMSLVIEMGLDRIKELPELWLGQNEFDFMTDFVCKQQPSRVSC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99967-1", "uniprot_id": "CITE2_HUMAN", "id": "Q99967-1", "name": "Cbp/p300-interacting transactivator 2", "aln": "MADHMMAMNHGRFPDGTNGLHHHPAHRMGMGQFPSPHHHQQQQPQHAFNALMGEHIHYGAGNMNATSGIRHAMGPGTVNGGHPPSALAPAARFNNSQFMGPPVASQGGSLPASMQLQKLNNQYFNHHPYPHNHYMPDLHPAAGHQMNGTNQHFRDCNPKHSGGSSTPGGSGGSSTPGGSGSSSGGGAGSSNSGGGSGSGNMPASVAHVPAAMLPPNVIDTDFIDEEVLMSLVIEMGLDRIKELPELWLGQNEFDFMTDFVCKQQPSRVSC", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "********************************************************************************************************************************************:****************************:***.******.:***..*** .*.*.** .**********************************************************************", "identical_positions": 257, "similar_positions": 11, "identity": "95.19%" }, { "cls_id": "homologset.agr.MGI:1306785", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O70199-1", "uniprot_id": "UGDH_RAT", "id": "O70199-1", "name": "UDP-glucose 6-dehydrogenase", "aln": "MVEIKKICCIGAGYVGGPTCSVIARMCPEIRVTVVDVNEARINAWNSPTLPIYEPGLKEVVESCRGKNLFFSTNIDDAIREADLVFISVNTPTKTYGMGKGRAADLKYIEACARRIVQNSNGYKIVTEKSTVPVRAAESIRRIFDANTKPNLNLQVLSNPEFLAEGTAIKDLKNPDRVLIGGDETPEGQRAVQALCAVYEHWVPKEKILTTNTWSSELSKLAANAFLAQRISSINSISALCESTGADVEEVATAIGMDQRIGNKFLKASVGFGGGCFQKDVLNLVYLCEALNLPEVARYWQQVIDMNDYQRRRFASRIIDSLFNTVTDKKIAILGFAFKKDTGDTRESSSIYISKYLMDEGAHLHIYDPKVPREQIVVDLSHPGVSAD-DQVSRLVTISKDPYEACDGAHALVICTEWDMFKELDYERIHKRMLKPAFIFDGRRVLDGLHNELQTIGFQIETIGKKVSSKRIPYTP-GEIPKFSLQDPPNKKPKV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70475-1", "uniprot_id": "UGDH_MOUSE", "id": "O70475-1", "name": "UDP-glucose 6-dehydrogenase", "aln": "MVEIKKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNEARINAWNSPTLPIYEPGLKEVVESCRGKNLFFSTNIDDAIREADLVFISVNTPTKTYGMGKGRAADLKYIEACARRIVQNSNGYKIVTEKSTVPVRAAESIRRIFDANTKPNLNLQVLSNPEFLAEGTAIKDLKNPDRVLIGGDETPEGQKAVRALCAVYEHWVPKEKILTTNTWSSELSKLAANAFLAQRISSINSISALCEATGADVEEVATAIGMDQRIGNKFLKASVGFGGSCFQKDVLNLVYLCEALNLPEVARYWQQVIDMNDYQRRRFASRIIDSLFNTVTDKKIAILGFAFKKDTGDTRESSSIYISKYLMDEGAHLHIYDPKVPREQIVVDLSHPGVSAD-DQVSRLVTISKDPYEACDGAHALVICTEWDMFKELDYERIHKKMLKPAFIFDGRRVLDGLHSELQTIGFQIETIGKKVSSKRIPYTP-GEIPKFSLQDPPNKKPKV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60701-1", "uniprot_id": "UGDH_HUMAN", "id": "O60701-1", "name": "UDP-glucose 6-dehydrogenase", "aln": "MFEIKKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEVVESCRGKNLFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRAADLKYIEACARRIVQNSNGYKIVTEKSTVPVRAAESIRRIFDANTKPNLNLQVLSNPEFLAEGTAIKDLKNPDRVLIGGDETPEGQRAVQALCAVYEHWVPREKILTTNTWSSELSKLAANAFLAQRISSINSISALCEATGADVEEVATAIGMDQRIGNKFLKASVGFGGSCFQKDVLNLVYLCEALNLPEVARYWQQVIDMNDYQRRRFASRIIDSLFNTVTDKKIAILGFAFKKDTGDTRESSSIYISKYLMDEGAHLHIYDPKVPREQIVVDLSHPGVSED-DQVSRLVTISKDPYEACDGAHAVVICTEWDMFKELDYERIHKKMLKPAFIFDGRRVLDGLHNELQTIGFQIETIGKKVSSKRIPYAPSGEIPKFSLQDPPNKKPKV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O02373-1", "uniprot_id": "UGDH_DROME", "id": "O02373-1", "name": "UDP-glucose 6-dehydrogenase", "aln": "----MKVCCIGAGYVGGPTCAVMALKCPDIVITLVDKSSERIAQWNSDKLPIYEPGLDEVVKKCRNVNLFFSTDIETAIKEADLIFISVNTPTKTCGNGKGRAADLKYVESAARMIAEIAQSNKIVVEKSTVPVRAAESIMHILRANQKPGIHYDILSNPEFLAEGTAINDLLNADRVLIGGEETPEGHQAVEKLSWIYEHWIPKQNILTTNTWSSELSKLAANAFLAQRISSINSLSAVCEATGADVSEVARAVGLDSRIGSKFLQASVGFGGSCFQKDILNLIYICENLNLPEVAAYWQQVIDMNEYQKRRFSQKIIESLFNTVSDKRIAILGFAFKKNTGDTRETAAITVCQTLLEEGAALDIYDPKVEPEQIIDDLTHPSVTESPEKVKKAVQIHSDPYSAVRATHALVICTEWDEFVDLDFKRIYQSMMKPAYIFDGRKILD--HERLQQIGFHVQTIGKKYQRTGLLRSW-GIVPQL------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:*************:*:* **:* :*:** .. ** *** .********.***:.**. ******:*: **:****:********** * **********:*:.** *.: ::. ***.************* :*: ** **.:: ::*************:** *.*******:*****::**. *. :****:*:::*****************************:**:**:*****.*** *:*:*.***.***:*******.*****:***:*:** ******* *********:**:***:.:**:******:**:**********:******:::* :.: *::*** *.****** ***: **:**.*: . ::*.: * * .***.* .:**:******* * :**::**:: *:***:*****::** *..** ***:::***** . . : : * :*:: ", "identical_positions": 315, "similar_positions": 111, "identity": "63.64%" }, { "cls_id": "homologset.agr.MGI:1306794", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9PU64-1", "uniprot_id": "E9PU64_RAT", "id": "E9PU64-1", "name": "Scinderin", "aln": "-----------------------------------------------------MAQELQHPEFARAGKQAG-LQVWRVEKLELVPVPQGAYGDFYVGDAYLVLHTTKS-------------SRG--FSYRLHFWLGKECSQDESTAAAIFTVQMDDYLGGKPVQSRELQGYESTDFVGYFKGGLKYKAGGVASGLNHVLTNDLTAKRLLHVKGRRVVRATEVP-LSWQSFNKGDCFIIDLGTEIYQWCGSSCNKYERLKASQVATGIRDNERKGRSQLIVVEEGSEPPE---LMKVLGR--KPELPD-GDNDDDVIADISNRKMAKLYMVSDASGSMKVTLVAEENPFSMGMLLPEECFILDHGAAKQIFVWKGKNANPQERKTAMKTAEEFLHKMNYSANTQIQVLPEGGETPIFKQFFKDWKDKDQSDG--FGKVYITEKVAQIKQIPFDASKLHSSPQMAAQHNMVDDGSGGVEIWRVEN-----SGRVQIDPSSYGEFY---GGDCYIILYTYPR-------------GQIIYTWQGADATRDELTMSAFLTVQLDRSLGGQAVQVRVSQGKEPAHLLSLFKDKPLIIYKNGTSKKGGQAPAPPTRLFQVRRN-LASITRIVEVDVDANSLNSNDTFVLKLPR-NNGFIWIGKGAS-------------------QEEEKG--AEYVADVLKCKTTRIQEGKEP-----------GMNSGTLLE---EEETTRLHHCWKHR------------------LKIILLGFMAALTK-------------LEDSLLKKFRESSPRMTWPKMMSCYLMRGNRSSFG-LAKMPMKLRKRNQ-------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60604-1", "uniprot_id": "SCIN_MOUSE", "id": "Q60604-1", "name": "Scinderin", "aln": "-----------------------------------------------------MAQELQHPEFARAGQQAG-LQVWRVEKLELVPVPQGAYGDFYVGDAYLVLHTTKS-------------SRG--FSYRLHFWLGKECSQDESTAAAIFTVQMDDYLGGKPVQSRELQGYESTDFVGYFKGGLKYKAGGVASGLNHVLTNDLTAKRLLHVKGRRVVRATEVP-LSWESFNKGDCFIIDLGTEIYQWCGSSCNKYERLKASQVAIGIRDNERKGRSQLIVVEEGSEPSE---LMKVLGR--KPELPD-GDNDDDVVADISNRKMAKLYMVSDASGSMKVTLVAEENPFSMGMLLSEECFILDHGAAKQIFVWKGKNANPQERKTAMKTAEEFLQKMKYSTNTQIQVLPEGGETPIFKQFFKDWKDKDQSDG--FGKVYITEKVAQIKQIPFDASKLHSSPQMAAQHNMVDDGSGGVEIWRVEN-----SGRVQIDPSSYGEFY---GGDCYIILYTYPR-------------GQIIYTWQGANATRDELTMSAFLTVQLDRSLGGQAVQVRVSQGKEPAHLLSLFKDKPLIIYKNGTSKKEGQAPAPPTRLFQVRRN-LASITRIVEVDVDANSLNSNDTFVLKLPR-NNGFIWIGKGAS-------------------QEEEKG--AEYVADVLKCKASRIQEGKEPEEFWNSLGGRGDYQTSPLLETRAEDHPPRLYGCSNKT------------------GRFIIEEVPGEFTQDDLAEDDVMLLDAWEQIFIWIGKDANEVEKKESVKSAKMYLETDPSGR-DKRTPIVIIKQGHEPPTFTGWFLGWDSSRW--------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y6U3-1", "uniprot_id": "SCIN_HUMAN", "id": "Q9Y6U3-1", "name": "Scinderin", "aln": "-----------------------------------------------------MARELYHEEFARAGKQAG-LQVWRIEKLELVPVPQSAHGDFYVGDAYLVLHTAKT-------------SRG--FTYHLHFWLGKECSQDESTAAAIFTVQMDDYLGGKPVQNRELQGYESNDFVSYFKGGLKYKAGGVASGLNHVLTNDLTAKRLLHVKGRRVVRATEVP-LSWDSFNKGDCFIIDLGTEIYQWCGSSCNKYERLKANQVATGIRYNERKGRSELIVVEEGSEPSE---LIKVLGE--KPELPD-GGDDDDIIADISNRKMAKLYMVSDASGSMRVTVVAEENPFSMAMLLSEECFILDHGAAKQIFVWKGKDANPQERKAAMKTAEEFLQQMNYSKNTQIQVLPEGGETPIFKQFFKDWRDKDQSDG--FGKVYVTEKVAQIKQIPFDASKLHSSPQMAAQHNMVDDGSGKVEIWRVEN-----NGRIQVDQNSYGEFY---GGDCYIILYTYPR-------------GQIIYTWQGANATRDELTTSAFLTVQLDRSLGGQAVQIRVSQGKEPVHLLSLFKDKPLIIYKNGTSKKGGQAPAPPTRLFQVRRN-LASITRIVEVDVDANSLNSNDVFVLKLPQ-NSGYIWVGKGAS-------------------QEEEKG--AEYVASVLKCKTLRIQEGEEPEEFWNSLGGKKDYQTSPLLETQAEDHPPRLYGCSNKT------------------GRFVIEEIPGEFTQDDLAEDDVMLLDAWEQIFIWIGKDANEVEKKESLKSAKMYLETDPSGR-DKRTPIVIIKQGHEPPTFTGWFLGWDSSKW--------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LYK7-1", "uniprot_id": "Q1LYK7_DANRE", "id": "Q1LYK7-1", "name": "Macrophage-capping protein", "aln": "-------------------------------------------------------MVLHHKEFEKAGKYSG-LQIWRIEKMEIVPVPESFYGSFYTGDAYLVLHTVKQ-------------KDS--SFYDLHFWLGKECSQDESTAAAIFSTQMDDYLGGKPVQYREIQGFESTVFTSYFKGGIKYKSGGVASGFQHVITNDLTARRLFHIKGRRTVRATEVP-LSWASFNNGDCFIVDLGPVIYQWCGSKCNKFERIKAAQVGTGIRDNERSGRAKLVVIEEGQEPAE---MTEVLGV--KPEIPE-GDDSEDAVADVSNRKMASLYMVSDATGKMQVSLVSKDNPFDQSNLLSDECFILDHGKNKMIFVWKGHNANPSERKEAMKTAESFIKQMGYPQNTQIQVLPEGGETPIFKQFFKSWKEKDQAEG--LGRVFVTERIAKIKQEKFDASKLHESRQMAAQYNMVDDGAGKTEIWRVECGATKGDTKVPVDPETYGQFY---GGDCYIILYRYSK-------------GEIIYTWQGSRSTIDELTASAFLTVELDRSLGGNAVQVRVTQGKEPPHLLSLFKDKPLIVYKDGTSRKGGQAPAAPTRLFQVRKN-LGTITRISEVDAKASSLNSNDVYLLKLPQ-GDGYIWKGKGAS-------------------EEEEKA--AKYMSEKLNCKTKMVVEGKEPDVFWMALGGKTEYQTSGLLESRTIAHPPRLFACSNKT------------------GKFIIEEVPGEFNQDDLAEDDVMLLDVWDSVFVWIGKDANEVERTESVKSAKIYIETDPSGR-DKGTPLVVVKQGHEPPTFTGWFLAWDASRWDGDLMARALNSLSVV-----------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q07171-1", "uniprot_id": "GELS_DROME", "id": "Q07171-1", "name": "Gelsolin", "aln": "MDASGAATMAVLSSLLVFLALSSSLCSAGTLNARPAFPVQSGEIQPSGQNSKQAARRVMHPSFANAGRTPG-LEIWRIENFEPVIYPKTNYGKFYTGDSFIVLNTIEN-------------KKDKKLSWDVHFWLGLETSTDEAGAAAILTVQLDDLLNGGPVQHREVQDHESQLFLSYFKNGIRYEQGGVGTGFKHVETNAQGETRLFQVKGKRNVRVRQVN-LSVSSMNTGDCFILDAGSDIYVYVGSQAKRVEKLKAISAANQIRDQDHNGRARVQIVDDFSTDADKQHFFDVLGSGSADQVPDESTADEDSAFERTDAAAVSLYKVSDASGKLKVDIIGQK-PLTQAMLDTRECFILDTGSG--IFVWVGKGATQKEKTDAMAKAQEFLRTKKYPAWTQIHRIVEGSESAPFKQYFDTWRDAGMSHSRLIRSALGIGSDELLNDDEIDSVVTQLKKSGGRAFGFMPDHGQNVIETITQYVAKPGSDEIVVSTVPFDEKLPLLGFASYVLTYNYEANNGD--------TGSLTYVWHGVKASAAARKR----AFEEGLVGSKDGLLVQTNQGHEPRHFYKIFKGKLLTSFT---------ALPVTAQLFRIRGT-VESDVHASEVAADSSSLASSDAFVLHSGKSHKIYIWNGLGAS-------------------AFEKQAAVDRFSDYWDDVELEQVEEGAEPDEFWEELNGEGQYDRS-LGDDGAPLLESRLFHCHLSS------------------GGFLKVEEVAQYEQEDLDSDDIMLLDAGDEIYLWVGYGVSEEENGKLLDTAKLYFNLEPTARSFDTVSIIRVPQGKEPRVFKRMFPNWDDNYWQNQPSYEDMKQLVIDANNEV------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q23989-1", "uniprot_id": "QUAI_DROME", "id": "Q23989-1", "name": "Villin-like protein quail", "aln": "-------------------------------------MELSLSPKETEIRPNTIPDLKVDATFRKVAKHAITFAIWKIDEDRLEAVQRSHYGTFYDSCAYIIYAASLSGHYANHETITREQKPNVSLERYIHYWLGKNVSEQNRSNVVHKIQELDSYLGNISSIYRETQNLESARFLSYFKKGYDVRSG--------ALISAPQRPRLFQLYARKWLRSIEVATIDWSHFNSDYVMVLQTDNLTYVWIGRSSSGIERRSALDWVQ-----KHCSGSPITIVDDGYEQAMSQEHKELWNTMLPLKKRMVCQASQLVSEYADYNSNKFRIYKCNQRGRLHLDQLDVGMPAKDDLSDAHGVYLLDNYGQS-IWLWVGGQAPQADALSAMGNGRAFVKKKKYPDNTLVVRVLEGHEPVEFKRLFANWLNVWQENT-------RGHKPVSTKFGKLDAHSLCERPKMAADTQLVDDGRGERVIYRVFG------DQVQEVPISKTVVFT--TNASFVVKYSVQCATVVPADLASVGIKTIIYQWNGSEASVESISRADKFAKASFDGLKEPGMFVQLYEFDEPPHFLQIFEGKLIIRRGQRTEMPYNGNSNALLDTFLLKVYGDASYNAKAVEETHLSSISSKDCYVIKTNH---VWVWCGQSSTGDAREMAKAVGALMGENSLVLEGKESKEFWQSVAMYFNQTLVINGNGNSCSSSTSSSSGAGSMCNGSSNGGNISPTLSNNCYLNTSVPSKPRPPVQLFLVWWQQSSLRYEEILGFDQQDLSSDCTYILDTGSLTYVWLGSQAPNQER--YTAIAQSYVQNAPFGR-RSATALAVVRQFQEPNVFKGFFESWQNDYGKNFHSYEKMRKDLGNKVTSNCCFASEGSALILNNRQKDFDGHKKYPLTVLIQEMDMLPPDINPLKREVHLTHDDFVSVFNMSFYEFDELPKWKKMELKKQFKLF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * ...: . : :*:::: . . :* ** . :::: : . . :*:*** : * :: .. ::*. *.. . ** *. ** * .*** * . * . . **::: .:: :* :* :. :*.. :::: . * : * ... *: .* . .: . : : :::: . .: . : .: .: * ::: : * . ::** *::* * * : ** ... *:: *. * : : ** *. **: * * : . : :*: . . :: * . .: . .::: * : * *:* :: . : .: :: : .** *: .:*:.* : * :: : .. .*: *.* :::: : ::* * .:: * : : : : :* . . . * : : . : . . .: : : ", "identical_positions": 72, "similar_positions": 175, "identity": "7.5%" }, { "cls_id": "homologset.agr.MGI:1306796", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9EPV5-1", "uniprot_id": "APAF_RAT", "id": "Q9EPV5-1", "name": "Apoptotic protease-activating factor 1", "aln": "--MDAKARNCLLQHKEALEKDIKTSYIMDHMISNG---VLTVVEEEKVKSQATQYQRAAALIKMILNKDNYAYISFYNALLHEGYKDLAGLLHSGLPLVSSSSGKDTDGGNTSFVRTVLCEGGVPQRPVIFVTRKKLVSAIQQKLWKLNGEPGWVTIYGMAGCGKSVLAAEAVRDHALLEGCFSGGVHWVSIGKQDKS-GLLMKLQNLCTRLGQEES----FSQRLPLNIEEAKDRLR-VLMLRKHPRSLLILDDVWDPWVLKAFDNQCQILLTTRDKSVTDSVMGPKYVIP----VESGLGKEKGLEILSLFVNMKKEDLPVEAHSIIKECKGSPLVVSLVGALLRDFPNRWAYYLRQLQNKQFKRIRKSSSYDYEALDEAMSISVEMLREDIKDYYTDLSILQKDVKVPTKVLCVLWDLETEEVEDILQEFVN--KSLLFCNRNGKSFCYYLHDLQVDFLTEKNRSQLQDLHRKMVTQFQRYHQPHTLSPGQEDCMYWYNFLAYHMASAGMHKELCALMFSLDWIKAKTELVGPAHLIHEFVEYRHILDEKDCAVCENFQEFLSLNGHLLGRQPFPNIVQLGLCEPETSEVYQQAKLQAKQEVDTGRLYLEWINKKTIKNLSRLVVRPHTDAVYHACFSQDGQRIASCGADKTLQVFKAETGE--KLLDIKAHEDEVLCCAFSSDDSYIATCSVDKKVKIWDSGTGKLVHTYE-EHSEQVN-----------------------CCHFTNKSNHLLLATGSNDSFL---KLWDLNQKECRNTMFGHTNSVTHCRFSPDDELLASCSADGTLKLWDVRSAN----EKKSINVK------------------------------------RFFLSSEDPPEDVEVIVKCCSWSADGDRIIVAAKNKVLLLDIHTSG-LLTEIHTGHHSTIQYCDFSPYDHLAVIALSQYCVELWNIDSRVKVADCRGH----LSWVHG---------------------VMFSPDGSSFLTASDDQTIRVWETRK-------VCKNSAIVLKQEIDVVFQENEMMVLAVDNIRGLQLIAGKTGQIDYLPEAQVS---CCCLSPHLEYVAFGDEEGAIKIIELPNNRVFSSGIGHKKAVRHIQFTADGKTLISSSEDSVIQVWNWQTEEYVFLQAHQETVKDFRLLRDS---RLLSWSFDGTVKVWNVITG---RIERDFTCHQGTVLSCAISSDATKFSSTSADKTAKIWSFE---LPSPLHELKGHNSCVRCSAFSLDGILLATGDDNGEIRIWNVSDGQ----------------LLHLCAPISIEEGTATHGGWVTDVCFSPDRKMLVSAGGYLKWWN----VVTGESSQTFYTNGTNLKKIHVSPDFRTYVTVDNLGILYILQVLE-------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88879-1", "uniprot_id": "APAF_MOUSE", "id": "O88879-1", "name": "Apoptotic protease-activating factor 1", "aln": "--MDAKARNCLLQHREALEKDIKTSYIMDHMISNG---VLSVIEEEKVKSQATQYQRAAALIKMILNKDNCAYISFYNALLHEGYKDLAALLQSGLPLVSSSSGKDTDGGITSFVRTVLCEGGVPQRPVIFVTRKKLVHAIQQKLWKLNGEPGWVTIYGMAGCGKSVLAAEAVRDHSLLEGCFSGGVHWVSIGKQDKS-GLLMKLQNLCMRLDQEES----FSQRLPLNIEEAKDRLR-VLMLRKHPRSLLILDDVWDPWVLKAFDNQCQILLTTRDKSVTDSVMGPKHVVP----VESGLGREKGLEILSLFVNMKKEDLPAEAHSIIKECKGSPLVVSLIGALLRDFPNRWAYYLRQLQNKQFKRIRKSSSYDYEALDEAMSISVEMLREDIKDYYTDLSILQKDVKVPTKVLCVLWDLETEEVEDILQEFVN--KSLLFCNRNGKSFCYYLHDLQVDFLTEKNRSQLQDLHRKMVTQFQRYYQPHTLSPDQEDCMYWYNFLAYHMASANMHKELCALMFSLDWIKAKTELVGPAHLIHEFVAYRHILDEKDCAVCENFQEFLSLNGHLLGRQPFPNIVQLGLCEPETSEVYRQAKLQAKQEGDTGRLYLEWINKKTIKNLSRLVVRPHTDAVYHACFSQDGQRIASCGADKTLQVFKAETGE--KLLDIKAHEDEVLCCAFSSDDSYIATCSADKKVKIWDSATGKLVHTYD-EHSEQVN-----------------------CCHFTNKSNHLLLATGSNDFFL---KLWDLNQKECRNTMFGHTNSVNHCRFSPDDELLASCSADGTLRLWDVRSAN----ERKSINVK------------------------------------RFFLSSEDPPEDVEVIVKCCSWSADGDKIIVAAKNKVLLFDIHTSG-LLAEIHTGHHSTIQYCDFSPYDHLAVIALSQYCVELWNIDSRLKVADCRGH----LSWVHG---------------------VMFSPDGSSFLTASDDQTIRVWETKK-------VCKNSAIVLKQEIDVVFQENETMVLAVDNIRGLQLIAGKTGQIDYLPEAQVS---CCCLSPHLEYVAFGDEDGAIKIIELPNNRVFSSGVGHKKAVRHIQFTADGKTLISSSEDSVIQVWNWQTGDYVFLQAHQETVKDFRLLQDS---RLLSWSFDGTVKVWNVITG---RIERDFTCHQGTVLSCAISSDATKFSSTSADKTAKIWSFD---LLSPLHELKGHNGCVRCSAFSLDGILLATGDDNGEIRIWNVSDGQ----------------LLHSCAPISVEEGTATHGGWVTDVCFSPDSKTLVSAGGYLKWWN----VATGDSSQTFYTNGTNLKKIHVSPDFRTYVTVDNLGILYILQVLE-------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14727-1", "uniprot_id": "APAF_HUMAN", "id": "O14727-1", "name": "Apoptotic protease-activating factor 1", "aln": "--MDAKARNCLLQHREALEKDIKTSYIMDHMISDG---FLTISEEEKVRNEPTQQQRAAMLIKMILKKDNDSYVSFYNALLHEGYKDLAALLHDGIPVVSSSSGKDSVSGITSYVRTVLCEGGVPQRPVVFVTRKKLVNAIQQKLSKLKGEPGWVTIHGMAGCGKSVLAAEAVRDHSLLEGCFPGGVHWVSVGKQDKS-GLLMKLQNLCTRLDQDES----FSQRLPLNIEEAKDRLR-ILMLRKHPRSLLILDDVWDSWVLKAFDSQCQILLTTRDKSVTDSVMGPKYVVP----VESSLGKEKGLEILSLFVNMKKADLPEQAHSIIKECKGSPLVVSLIGALLRDFPNRWEYYLKQLQNKQFKRIRKSSSYDYEALDEAMSISVEMLREDIKDYYTDLSILQKDVKVPTKVLCILWDMETEEVEDILQEFVN--KSLLFCDRNGKSFRYYLHDLQVDFLTEKNCSQLQDLHKKIITQFQRYHQPHTLSPDQEDCMYWYNFLAYHMASAKMHKELCALMFSLDWIKAKTELVGPAHLIHEFVEYRHILDEKDCAVSENFQEFLSLNGHLLGRQPFPNIVQLGLCEPETSEVYQQAKLQAKQEVDNGMLYLEWINKKNITNLSRLVVRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGE--KLLEIKAHEDEVLCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYD-EHSEQVN-----------------------CCHFTNSSHHLLLATGSSDCFL---KLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSAN----ERKSINVK------------------------------------QFFLNLEDPQEDMEVIVKCCSWSADGARIMVAAKNKIFLFDIHTSG-LLGEIHTGHHSTIQYCDFSPQNHLAVVALSQYCVELWNTDSRSKVADCRGH----LSWVHG---------------------VMFSPDGSSFLTSSDDQTIRLWETKK-------VCKNSAVMLKQEVDVVFQENEVMVLAVDHIRRLQLINGRTGQIDYLTEAQVS---CCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEIQVWNWQLDKCIFLRGHQETVKDFRLLKNS---RLLSWSFDGTVKVWNIITG---NKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFD---LLLPLHELRGHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGE----------------LLHLCAPLS-EEGAATHGGWVTDLCFSPDGKMLISAGGYIKWWN----VVTGESSQTFYTNGTNLKKIHVSPDFKTYVTVDNLGILYILQTLE-------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9I9H8-1", "uniprot_id": "APAF_DANRE", "id": "Q9I9H8-1", "name": "Apoptotic protease-activating factor 1", "aln": "--MEERARSRLLRSKATLEQDIKASYLMDHMISDG---VLTNDEEAKVLSKATRKEQAVALLETLLRKDNRAYISFYNALIRESYGDLASLLHSDLPLLSPEGEKSFADGVSPSVQAILSVGGVPQRPVVFVSRPPLLNLIREMLYQLRDTPGWVTVFGMAGSGKSVMAAEVVRDRSLIKECFPDGVHWLSVGQCERA-DLLVRMQSLCFRLEQCQSS--DTSQRPPSTVEEAKERLR-FLMLRRFPRSLLILDDVWDSSSLRSFDIQCRVLLTTRNRALTDSVSGVRYEVP----VENGLDEEKALEILALYVNGKMHKLPEQARSIVSECKGSPLVVSLIGALLREFPDRWSYYLRQLQQKQFKRIRKSSSYDYEALDQAMDASLQVLEAEHQELYRDLSVMQKDIKVPAKVLSVLWGLELEEVEDVLQEFVN--KSLLFRDCNQRPYRYYLHDLQLDFLAEQNRDQIAELHKKMVRQYQRFYSKRPPDSADKDSLYWYQFIPYHMAKAGLSKELYSLMFSLDWVKEKARIMGSAHLINDYVEYGEILDKENSEVRVQFQEFLSLNGHHLEQRPFPDVVQLALSQPDRSEVYRQALMQAQKRASRGQIYLNWVNKNIEEGLSRLVMHPHQGAVYYACFSKDGSKIASCGASKALRVFKSTSGE--KLLELQAHEEDVLCCAFSPDDRHIATCASDRKVKLWNVERGVLIREFEVEHEEQIN-----------------------HCQFTNTGRRVLLATCSNDKFTN-TRLWNPNKKTSQNTMFGHMEPVNHCCFSPNDLYLATSSSDGSLKLFEVSSAN----EWKSIDVD------------------------------------SFFPESD---EEIKAMVKCSTWSADGSQIICAARNTVFVFDVETSD-LLLKLKTSRLSTIQFCHACPNSSLLAVALSHYTVELWNFESSKKKAECSGH----LSWVHC---------------------VQFSPDGSLLLSSSDDQTIRLWETDR-------VHTSSAVALKRDTDVLSSHSDATIIAPDSSNRLQVLSGSTGAVVLESEELSSRIRCSCISRNAAFVALGSEDGTVQVIEVPSSKASVKLSGHTKTVHHCQFTDDCEILITSSEDSTIRVWKWRTGECMVLQGHMEPVRKFHLLSSSSSPHLFSWSFDGTVKVWDLTRG---QMLQDLVCHEGAVLSCDVSSDGRLFATTSANRTAKVWSSA---SWKMLFLLEGHKDCVRSCRFSWDNKRLATGDDNGEIRLWSMLDGA----------------LLKICPRDTKDSMNSYHAGWVTDLHFSPDNRVLVSTAGYIKWWS----VESGEALQTFYTMGGNLKKIHVSPDFSTFITVDSIGILYILKRLEGEGT---------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7KLI1-1", "uniprot_id": "APAF_DROME", "id": "Q7KLI1-1", "name": "Apoptosome protein Dark", "aln": "MDFETGEHQYQYKDILSVFEDAFVDNFDCKDVQDMPKSILSKEEIDHIIMSKDAVSGTLRLFWTLLSKQEEMVQKFVEEVLRINYKFLMSPIKTEQRQPSMMTRMYIEQRDRLYNDNQVFAKYN-------VSRLQPYLKLRQALLELR-PAKNVLIDGVLGSGKTWVALDVCLS-YKVQCKMDFKIFWLNLKNCNSPETVLEMLQKLLYQIDPNWTSRSDHSSNIKLRIHSIQAELRRLLKSKPYENCLLVLLNVQNAKAWNAFNLSCKILLTTRFKQVTDFLSAATTTHISLDHHSMTLTPDEVKSLLLKYLDCRPQDLPREVLTTN------PRRLSIIAESIRDGLATWDNWKHVNCDKLTTIIESSLNVLEPAEYRKMFDRLSVFPPSAHIPTILLSLIWFDVIKSDVMVVVNKLHKYSLVEKQPKESTISIPSIYLELKVKLENEYALHRSIVDHYNIPKTFDSDDLIPPYLDQYFYSHIGHHLKNIEHP----ERMTLFRMVFLDFRFLEQKIRHDSTAWNASGSILNTLQQLKFYKPYICDNDPKYERLVNAILDFLPKIEENLICSKYTDLLRIALMAED-EAIFEEAHKQVQRFDDR-----VWFTNHGRFHQHRQIINLGDNEGRHAVYLHNDFCLIALASGQILLTDVSLEGEDTYLLRDESDSSDILRMAVFNQQKHLITLHCNGSVKLWSLWPDCPGRRHSGGSKQQLVNSVVKRFIGSYANLKIVAFYLNEDAGLPEANIQLHVAFINGDVSILNWDEQDQEFKLSHVPVLKTMQSGIRCFVQVLKRYYVVCTSNCTLTVWDLTNGSSNTLELHVFNVENDTPLALDVFDERSKTATVLLIFKYSVWRLNFLPGLSVSLQSEAVQLPEGSFITCGKRSTDGRYLLLGTSEGLIVYDLKISDPVLRSNVSEHIECVDIYELFDPVYKYIVLCGAKGKQVVHVHTLRSVSGSNSHQNREIAWVHSADEISVMTKACLEPNVYLRSLMDMTRERTQLLAVDSKERIHLIKPAISRISEWSTITPTHAASNCKINAISAFNDEQIFVGYVDGVIIDVIHDTALPQQFIEEPIDYLKQVSPNILVASAHSAQKTVIFQLEKIDPLQPNDQWPLMMDVSTKYASLQEGQYIILFSDHGVCHLDIANPSAFVKPKDSEEYIVGFDLKNSLLFLAYENNIIDVFRLIFSCNQLRYEQICEEEIAQKAKISYLVATDDGTMLAMGFENGTLELFAVENRKVQLIYSIEEVHEHCIRQLLFSPCKLLLIS--CAEQLCFWNVTHMRNNQLEREQKRRRSRRHKQHSVTQEDAVDAAPIAADIDVDVTFVADEFHPVNRGTAELWRNKRGNAIRPELLACVKFVGNEARQFFTDAHFSHFYAIDDEGVYYHLQLLELSRLQPPPDPVTLDIANQYEDLKNLRILDSPLMQDSDSEGADVVGNLVLEKNGGVARATPILEEASS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: :. : :: :* .. : : :.: .*: * :: . . : *: :* *:: .* : ::: .* * . :: * : *:* ::: * :*. . * : *: *.**: :* :. . :: : :.*:.: : : . :* :*.* :: : *.. :.. : .** .* : . ..**:* :* :. .:*: .*::***** : :** : . . * :: .:* ::: : .** :. : * :*::. :*: * : : :* . *..* . * . * :.:: . : **:: *: . :: : : . **. :* . *: : * ** :*. : : :* : *: : : . :. .: ::*. : : .. : . ::.. : :: : * * : : : :**. . * :.:::::.* : . ::.:* *.:: . *..:: * ::. . :* : .:. : : .:.: * . : ** ** ::...::* *. :: .: * : .**:*. . : .. .:*: . :.: . :: :* ..* : : * .: .:: :. :* .. . . .::: :* ::: ... * : ::*. . . : ::.* . *:** :: .: : ::: *:. *. :* . : : . :: . : . :: : .: . : . .* ::*** : :: : : :*: ...: *:: :. . . : : . :.: .: ::. : : *. * . . . ..: .:: :: : . .. : : : :* *:.. :: . : : * : * * . . :* ::. . .: .::. : : *. :: : * :::: . *: *:* ** * : :: :*.: . : . . . .. .*: * .* :. . * . . : . * : :::.....* : ::*. *: * *: ** ", "identical_positions": 140, "similar_positions": 442, "identity": "9.54%" }, { "cls_id": "homologset.agr.MGI:1306797", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O08590-1", "uniprot_id": "AOC3_RAT", "id": "O08590-1", "name": "Amine oxidase [copper-containing] 3", "aln": "MTQKTTLVLLALAVITIFALVCVLLAGRSGDGGRLSQPLHCPSVLPSVQPQTHPGQSQPFADLSPEELTAVMSFLIKHLGPGLVDAAQARPSDNCVFSVELQLPAKAAALAHLDRGGPPPVREALAIIFFGGQPKPNVSELVVGPLPHPSYMRDVTVERHG-GPLPYYRRPVLTREYQDIQEMIFHRELPQASGLLHHCCFYKRQGHNLLKMTTAPRGLQSGDRATWFGIYYNLSGAGFYPHPIGLELLVDHKALDPALWTIQKVFYQGRYYESLTQLEDMFEAGLVNVVLVPDNGTGGSWSLKSSVPPGRAPPLQFHPEGPRFSVQGSQVRSSLWAFSFGLGAFSGPRIFDIRFQGERVAYEISVQEAIALYGGNSPASMSTCYMDGSFGIGKYSTPLTRGVDCPYLATYVDWHFLLESQTPKTLRDAFCVFEQNQGLPLRRHHSDFYSHYFGGVVETVLVVRSVATLLNYDYVWDMVFHSNGAIEVKFHATGYITSAFFFGAGEKFGNRVAEHTLGTVHTHNAHFKVDLDVAGLKNWAWAEDLAFVPMNVPWQPEFQMQRLQVTRKLLETEEEAAFPLGNATPRYLYLASNHSNKWGHRRGYRIQILSFAGKPLPQESPIEKAFTWGRYHLAVTQRKEEEPSSSSIYNQNDPWTPTVDFTDFIS-NETIAGEDLVAWVTAGFLHIPHAEDIPNTVTVGNGVGFFLRPYNFFDEDPSFYSPDSIYFRKDQDVTDCEVNSLACLSQTANCVPDLPAFSHGGFTYK----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70423-1", "uniprot_id": "AOC3_MOUSE", "id": "O70423-1", "name": "Amine oxidase [copper-containing] 3", "aln": "MTQKTTLVLLALAVITIFALVCVLLAGRSGDGGGLSQPLHCPSVLPSVQPRTHPSQSQPFADLSPEELTAVMSFLTKHLGPGLVDAAQARPSDNCVFSVELQLPAKAAALAHLDRGGPPPVREALAIIFFGGQPKPNVSELVVGPLPHPSYMRDVTVERHG-GPLPYYRRPVLDREYQDIEEMIFHRELPQASGLLHHCCFYKHQGQNLLTMTTAPRGLQSGDRATWFGLYYNLSGAGFYPHPIGLELLIDHKALDPALWTIQKVFYQGRYYESLTQLEDQFEAGLVNVVLVPNNGTGGSWSLKSSVPPGPAPPLQFHPQGPRFSVQGSQVSSSLWAFSFGLGAFSGPRIFDIRFQGERVAYEISVQEAIALYGGNSPASMSTCYVDGSFGIGKYSTPLIRGVDCPYLATYVDWHFLLESQAPKTLRDAFCVFEQNQGLPLRRHHSDFYSHYFGGVVGTVLVVRSVSTLLNYDYIWDMVFHPNGAIEVKFHATGYISSAFFFGAGEKFGNRVGAHTLGTVHTHSAHFKVDLDVAGLKNWAWAEDMAFVPTIVPWQPEYQMQRLQVTRKLLETEEEAAFPLGGATPRYLYLASNHSNKWGHRRGYRIQILSFAGKPLPQESPIEKAFTWGRYHLAVTQRKEEEPSSSSIFNQNDPWTPTVNFTDFIS-NETIAGEDLVAWVTAGFLHIPHAEDIPNTVTAGNSVGFFLRPYNFFDEDPSFHSADSIYFREGQDATACEVNPLACLSQTATCAPEIPAFSHGGFAYRDN--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q16853-1", "uniprot_id": "AOC3_HUMAN", "id": "Q16853-1", "name": "Amine oxidase [copper-containing] 3", "aln": "MNQKTILVLLILAVITIFALVCVLLVGRGGDGGEPSQLPHCPSVSPSAQPWTHPGQSQLFADLSREELTAVMRFLTQRLGPGLVDAAQARPSDNCVFSVELQLPPKAAALAHLDRGSPPPAREALAIVFFGRQPQPNVSELVVGPLPHPSYMRDVTVERHG-GPLPYHRRPVLFQEYLDIDQMIFNRELPQASGLLHHCCFYKHRGRNLVTMTTAPRGLQSGDRATWFGLYYNISGAGFFLHHVGLELLVNHKALDPARWTIQKVFYQGRYYDSLAQLEAQFEAGLVNVVLIPDNGTGGSWSLKSPVPPGPAPPLQFYPQGPRFSVQGSRVASSLWTFSFGLGAFSGPRIFDVRFQGERLVYEISLQEALAIYGGNSPAAMTTRYVDGGFGMGKYTTPLTRGVDCPYLATYVDWHFLLESQAPKTIRDAFCVFEQNQGLPLRRHHSDLYSHYFGGLAETVLVVRSMSTLLNYDYVWDTVFHPSGAIEIRFYATGYISSAFLFGATGKYGNQVSEHTLGTVHTHSAHFKVDLDVAGLENWVWAEDMVFVPMAVPWSPEHQLQRLQVTRKLLEMEEQAAFLVGSATPRYLYLASNHSNKWGHPRGYRIQMLSFAGEPLPQNSSMARGFSWERYQLAVTQRKEEEPSSSSVFNQNDPWAPTVDFSDFIN-NETIAGKDLVAWVTAGFLHIPHAEDIPNTVTVGNGVGFFLRPYNFFDEDPSFYSADSIYFRGDQDAGACEVNPLACLPQAAACAPDLPAFSHGGFSHN----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N4I9-1", "uniprot_id": "A0A8M1N4I9_DANRE", "id": "A0A8M1N4I9-1", "name": "Amine oxidase", "aln": "MDSLIKYIVILLALISVILNIVLICLNSNKPPKCMSQ-----SQASLNLQDTHSDRSLVFADLTPEEYKAVRDYMWAQKDLKISHSVLAKPSDNFLFLIDLSLPKKADVLRYLDKDGQKPAREASVVVFYG--EHRYLKEYVVS-LSGPLTHRDVTEQKYKTKTLPFTARTVTIGEYAQLFTLLYG-VFQKLETPLRESFGYNLQTNKLLPFEGMPRGIKAGDRKTWISFFRDFS--GMYIHPVGFEMLINHESSNSSDWTVDKLLYNGQYFNSIDAFIKRYQAGDLEKIVYKKIEN--FASLKPREKPTGLGPQQYYLQGKRFSVKNNQVVYLDWNFAFGMSSLTGMRAFDIRFEGQRIAYELSVQEAMSVYGSTTPGMILTKFLDSSIGIGRFAHELVRGIDCPYGATYVDTHRYIDTNVTQRFRNSICVFEHDIGRPLRRHFSDFFHNSYGGMANSALVIRSITAIGNYDYIWDFIFYQSGSVEARVHATGYISSSFLVDGNLKYGHQVAENVLGNIHTHFISFKVDLDILGEKNIFQTKDMVYEEVPLPWMPTEKAKIPRLVEQQVKTEKEAAMLHGAKTPRYLHIASKQTNRWGHNRSYRLQVLSFAGDPLPESESTEKSMSWARYKVAITKHKDEEQTSSSLYSQNYMWKPFVDFSKYIEDNETIDNEDLVAWVTAGFLHIPHAEDIPNTVTVGNGGGVLIRPHNYFNEDPSIHSPDGVHFIPGSEN-DCEYNKMACLEKDQ-CTSTLEPFTYHGFEGVMQFE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . ::: **:*::: : :: . . ** * . **..:* ****: ** .** :: : . : .:. *:**** :* ::*.** ** .* :**:.. *.*** .::*:* : :.* **. *. * **** ::: .**: *.* ** :: ::: : : . *:.. *: : .:*: : ***:::*** **:.:: ::* *:: * :*:*:*::*:: :.: **::*::*:*:*::*: : ::** :: :: . . ***. * * *:: :* ****:..:* * *:**:.:::* * **:**:*:*:.**:*:***:::**..:*. : * ::*..:*:*::: * **:**** ***** * ::::..: :*:::****:: * *****.**:: : :**:. :.**:**:::: ****:** :*: .*::* :.:*****:*:*:... *:*::*. :.**.:*** ******: * :* ::*:.: :** * : : ::..: :: *::**: * *****::**:::*:*** *.**:*:*****.***:... :.::* **::*:*::*:** :***::.** * * *:*:.:*. **** .:************************.**. *.::**:*:*:****::*.*.::* ..: ** * :*** : *.. : .*:: ** ", "identical_positions": 282, "similar_positions": 278, "identity": "36.67%" }, { "cls_id": "homologset.agr.MGI:1306798", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6MG64-1", "uniprot_id": "VWA7_RAT", "id": "Q6MG64-1", "name": "von Willebrand factor A domain-containing protein 7", "aln": "MLPVEVPLSQLGPP-VLLLQLLLPPTSAFFPNIWS--LLAAPGSITHQDLTEEAALNVTLELFLEQPPPGRPHLHLEDYRGRTLLADDIFAAYFGSGFSSRRFRAALGEVSRANAAQDFLPASKSNPDLHFDAERLVQGRTRLEGALRETLVAARALEYTLARQRLGAALHALQDFYSHSNWVELGERQPHPHLLWPRRELWSLAQVGDPTCSDCEGLSCPGNMMN------LTMLTSGYFGTNPPKPPGKCSHGGRFDQSSSQPPRGGINKDSTSPSFSPHHRLHLQAAEVALLASIEALSLLRSRLGTRGFSRLLDITPASSLSFVLDTTGSMGEEINAAKIQARRIVEQRQGS--PMEPVSYILVPFHDPGFGPVFTTSDPDSFWQKLTEIHALGGGDEPEMCLSALELALLHTPPLSDIFVFTDASPKDAFLTNRVESLTRERRCRVTFLVTEDPSRAQGRG------RREALSPSRFEPYEAIALASGGEVIFTKDQHIRDVAAVVGESMAGLVTLPLEPPIFTPGEPCVFAVDSLLSKVTVRMHGDISGFWIKSPAGLSQGPEEGIGPLGHTRRFGQFWTVTMTDPPQTGSWEIQVAAEGTPRVRVQAQTSLDFLFHFGISAEDGPHPGLYPLT-QPVAGLQTQLLVEVTGLVSRQKLGDGQPQFSHAVLRRVSEGTHLGRVSLEPVGPPERGLLAASLPPTLLSVSVPFSLELVGQDVGGQCLRRSAPQPCSVAPVLLELSGPPDFLTPGSKAPLSLRVASFSGPQDVDLRSSVNPSFSLTSNLSRARLGLNESAWGCLWLEVPDSAAPDTVVTVTVTVTAVGQGASQVPPTHAFLQLLVLAQSSKDQLEDPTHSAAPVLPPTTPALLPSTLVTRGRAGRGTTG-KTWWG----------------------TVGGVLFLLGCTSW--------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JHA8-1", "uniprot_id": "VWA7_MOUSE", "id": "Q9JHA8-1", "name": "von Willebrand factor A domain-containing protein 7", "aln": "MLPVEVPLSHLGPPILLLLQLLLPPTSAFFPNIWS--LLAAPGSVTHQDLTEEAALNVTLVLFLEQPHPGRPRLHVEDYRGRTLLADDIFAAYFGPGFSSRRFRAALGEVSRANAAQDFLPAFKSNPDLHFDAERLVQGRTRLVGALRETLVAARALEYTLARQRLGAALHALQDFYSHSNWVELGERQPHPHLLWPRQELWSLAQVGDPTCSDCEGLSCPGNMLD------STLLTSGYFGMHPPKPPGKCSHGGHFDQSSSQPPRGGINKDSTSPSFSPHHKLHLQAAEVALLASIEAFSLLRSRLGDKAFSRLLDITPASSLSFVLDTTGSMGEEINAAKIQARRIVEQRQGS--PMEPVFYILVPFHDPGFGPVFTTSDPDSFWQKLNEIHALGGGDEPEMCLSALELALLHTPPLSDIFVFTDASPKDALLTNRVESLTRERRCRVTFLVTEDPSRTGGRR------RREALSPLRFEPYEAIARASGGEVIFTKDQYIQDVAAIVGESMAGLVTLPLDPPVFTPGEPCVFSVDSLLWQVTVRMHGDISSFWIKSPAGVSQGPEEGIGPLGHTRRFGQFWTVTMTDPPRTGTWEIQVAAAGTPRVRVQAQTSLDFLFHFGISVEDGPHPGLYPLT-QPVAGLQTQLLVEVTGLTSRQKLVGGQPQFSHVVLRRVPEGTQLGRVSLEPVGPPVRGLLAASLPPTLLSVSSPFSLELVGQGGGGESLRRTAPQPCSVAPVLLELSGPPDFLTPGSKAPLSLHIVSFSGPQDLDLRTSVNPSFSLTSNLSRARLGLNESAWGRLWLEVPDSAAPDSVVMVTV--TAAGQGASQVPPTHAFLRLLVLAQSSKDQLDGPAHSAAPVLPPVSPALLPSTLVTQGRAGGGMAG-KAWWG----------------------TVGGVLFLLGCTSW--------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y334-1", "uniprot_id": "VWA7_HUMAN", "id": "Q9Y334-1", "name": "von Willebrand factor A domain-containing protein 7", "aln": "MLPTEVPQSHPGPSALLLLQLLLPPTSAFFPNIWS--LLAAPGSITHQDLTEEAALNVTLQLFLEQPPPGRPPLRLEDFLGRTLLADDLFAAYFGPG-SSRRFRAALGEVSRANAAQDFLPTSRNDPDLHFDAERLGQGRARLVGALRETVVAARALDHTLARQRLGAALHALQDFYSHSNWVELGEQQPHPHLLWPRQELQNLAQVADPTCSDCEELSCPRNWLG------FTLLTSGYFGTHPPKPPGKCSHGGHFDRSSSQPPRGGINKDSTSPGFSPHHMLHLQAAKLALLASIQAFSLLRSRLGDRDFSRLLDITPASSLSFVLDTTGSMGEEINAAKIQARHLVEQRRGS--PMEPVHYVLVPFHDPGFGPVFTTSDPDSFWQQLNEIHALGGGDEPEMCLSALQLALLHTPPLSDIFVFTDASPKDAFLTNQVESLTQERRCRVTFLVTEDTSRVQGRA------RREILSPLRFEPYKAVALASGGEVIFTKDQHIRDVAAIVGESMAALVTLPLDPPVVVPGQPLVFSVDGLLQKITVRIHGDISSFWIKNPAGVSQGQEEGGGPLGHTRRFGQFWMVTMDDPPQTGTWEIQVTAEDTPGVRVQAQTSLDFLFHFGIPMEDGPHPGLYPLT-QPVAGLQTQLLVEVTGLGSRANPGDPQPHFSHVILRGVPEGAELGQVPLEPVGPPERGLLAASLSPTLLSTPRPFSLELIGQDAAGRRLHRAAPQPSTVVPVLLELSGPSGFLAPGSKVPLSLRIASFSGPQDLDLRTFVNPSFSLTSNLSRAHLELNESAWGRLWLEVPDSAAPDSVVMVTV--TAGGREANPVPPTHAFLRLLVSAPAPQDRHTTPTGSSDPILTTATPAFSPFTLVTQGRAGAGLAAGSPWWG----------------------TVGGVLLLLGLASW--------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RP01-1", "uniprot_id": "A0A8M1RP01_DANRE", "id": "A0A8M1RP01-1", "name": "", "aln": "-----MMALALTYLCAVVLLIYLPICQAFLPNFWSRVLTLSWDSYTHQHMTEQAILNITMETVSKMMESQHDVDYEELYTG-----------------LGRGFWHAVGEVASANVAMDFLSSTRSDPVYHFDSERVDGAIQMLREFWAQTILLTQAKEYQGARRSLGQLFHSLQDFYSHSNWVEMGQQTLYLHLLHPEEPSVPVASADTPTCAECYRYSCYNNLLKEMIHQTKPLLTTGYFSNYPVKPPGKCSHGGILDSSRHQGAEGGINKDSTSPLFSPHHFLHKEAAHLASTATLRVLQDLRHRVGPESFLRLFSVQQPPALVFVMDTTGSMFEEITAARLRAFSIIQARGKSRRTSLPGTFVLVPFHDPGFGPVMETDDPDRFMQNLENLTALGGGDEPEMCLSALQLALTHSPPLSEIFVFTDASPKDRHLQSAVQALILEKQTKVNFLLTEDPNIGGGGKGMRKMKRRETLSPGRFSLYSSLSSLSGGMTIFTSNKDIHKASAIVEDTTTSSKVTLFHTNVES-NSSNSFRVDRAVTKVMLHITGQLTDCELVSPSGVHQSLFGKDGPLAVMDSSKGLYRISLLPPLDIGVWQLTVKAIGPITFNALGDSSLDFLYYFAREAN-ETHPGLRKIEGSPIAGIPAFLVVAVTGLSPNE-----EASFSHVTLLGP-KGESLQKVLLNSSSSRWSGEELVGYMDSVP--RMPFSLRLSGKDRKGNLLERVSTEMIQPTHVQIQVHSAP-QLLPGHSSNVLFEIFNHGPNRHFSLLAEDDHGFLTHQDQQRLFIGTRGSVKREVEIRTPHTTQTGKAITLTLTVQAEDSPDSNYAVVHLTVIPEKPDKNPPACSSLHVESSCPSLCSQGNWKVSLLAKDRGHSGLASIELTQGEGRLILSEMTTQRHTEHFPKLHKESTGGVYLPLLQPQKNSSEINTHVGTEVHHGQRLEGVQLMYGDHPANISEWTKGKPILMHYSSSCCAPHAELLLLDKAGNMRRCHLKASQQRALRENNRAHSGESTSCLPMLLGHLVLIVLYVSF", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ::* : ** .**:**:** * : .* ***.:**:* **:*: . : . : * : * .* * *:***: **.* ***.: :.:* ***:**: . * :*:: ::* :: **: ** :*:************:*:: : *** *.. :*.. ***::* ** * : .:**:***. * ********** :* * * ..********** ***** ** :**.:* *::..:. ** *:* . * **:.: ..:* **:****** ***.**:::* ::: * * . * ::************: *.*** * *:* :: ***************:*** *:****:*********** * . *::* *:: :*.**:***.. * *** *** **. *.::: *** .***.:: *:..:*:* :: :. . :.. : ... * ** : :: ::: *:::. : .*:*: *. ***. :: ::: * * *:: * * .. ... .::*****::*. : .**** : .*:**: : *:* **** .. :. ***. * :* * :* *:. .. * .. :: ****.* *:. *. *.* :.: . * ::: ... * ** . : :.: ... :...* : : .* .: .* : . *. : :..*.:: ....: :*: * . . . .* : . . *: * * . . :*::* . . * :.*** : * .. ", "identical_positions": 294, "similar_positions": 259, "identity": "28.19%" }, { "cls_id": "homologset.agr.MGI:1306800", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7TSK3-1", "uniprot_id": "PCDH8_MOUSE", "id": "Q7TSK3-1", "name": "Protocadherin-8", "aln": "MSPAKRWGSPCLFPLQLFSLCWVLSVAQSKTVRYSTFEEDAPGTVIGTLAEDLHMKVSG--DTSFRLMKQFNSSLLRVREGDGQLTVGDAGLDRERLCGPSPQCVLAFDVVSFSQEQFRLVHVEVEVRDVNDHAPRFPRAQIPVEVSESAPVGTRIPLEVPVDEDVGANGLQSVRLAEPHSPFRVELQTRADGAQCADLVLLQELDRESQASYSLELVAQDGGRPPRSATAALSVRVLDANDHSPAFPQGAVAEVELAEDAPVGSLLLDLDAADPDEGPNGDVVFTFGARTPPEARHLFRLDPRSGRLTLAGQVDYERQDTYELDVRAQDRGPGPRTATCKVIVRIRDVNDNAPEISITPLAAPGAPATSPFAAAAAAAALGGADAASSTGSGTQEAGITSLVPEGAARESLVALVSTSDRDSGANGQVRCALYGHEHFRLQPAYAGSYLVVTAASLDRERIAEYNLTLVAEDRGTPPLRTVRPYTVRVGDENDNAPIFTKPVYEVSVRENNPPGAYLATVAARDPDVGRNGQVTYRLVEAEVGRSGEAVSTYVSVDPATGAIYALRSFDYETLRQLDVRVQASDGGSPQLSSNALVQVRVLDQNDHSPILVHPAPANGSLEVAVPGRSTKDTAVARIQARDADEGANGELAFDLLQQEPREAFSIGRHTGEIMLTGDLSQEPPGRVFKALLVISDGGRPPLTTTATVSFVVTAGGG--SAVPASSGSPEHSRPPGSRLAPSGPSLQWDTPLIVIIVLAGSCTLLLAAIIAIATTCNRRKKEVRKGGALREERPGAAGGGASAPGSPDETARGTGPRPNMFDVLTFPGSGKAPFGSPAADAPPPAVAAAEVPGSEGGSATGESACHFEGQQRLRGAHAEPYGASPGFGKEPAAPPVAVWKGHSFNTISGREAEKFSGKDSGKGDSDFNDSDSDISGDALKKDLINHMQSGLWACTAECKILGHSDRCWSPSCAGP-NVHPPPHPPAQMSTFCKSTSLPRDPLRRDNYYQAQLPKTVGLQSVYEKVLHRDYDRTVTLLSPPRPGRLPDLQEIGVPLYESPPGSRYVSPKKGINENV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZE55-1", "uniprot_id": "PCDH8_RAT", "id": "D3ZE55-1", "name": "Protocadherin-8", "aln": "MSPVKRWGSPCLFPLQLFSLCWVLSVAQSKTVRYSTFEEDAPGTVIGTLAEDLHMKVSG--DTSFRLMKQFNSSLLRVREGDGQLTVGDAGLDRERLCGQSPQCVLAFDVVSFSQEQFRLVHVEVEVRDVNDHAPRFPRAQIPVEVSESAPVGTRIPLEVPVDEDVGANGLQSVRLAEPHSPFRVELQTRADGAQCADLVLLQELDRESQASYSLELVAQDGGRPPRSATAALSVRVLDANDHSPAFPQGAVAEVELAEDAPVGSLLLDLDAADPDEGPNGDVVFTFGARTPPEARHLFRLDPRSGRLTLAGQVDYERQDTYELDVRAQDRGPGPRTATCKVIVRIRDVNDNAPDISITPLAAPGAPATSPFAAAAAAAALGGADAASSAGSGTQETGVTSLVPEGAARESLVALVSTSDRDSGANGQVRCALYGHEHFRLQPAYAGSYLVVTAASLDRERIAEYNLTLVAEDRGAPPLRTVRPYTVRVGDENDNAPLFTKPVYEVSVRENNPPGAYLATVAARDPDLGRNGQVTYRLVEAEVGRSGEAVSTYVSVDPATGAIYALRSFDYETLRQLDVRVQASDGGSPQLSSNALVQVRVLDQNDHSPVLVHPAPANGSLEVAVPGRSTKDTAVARIQARDADEGANGELAFDLLQQEPREAFSIGRHTGEIVLTGDLSQEPPGRVFKALLVISDGGRPPLTTTATVSFVVTAGGG--SAVPASAGSPEHFRPPGSRLAPSGPSLQWDTPLIVIIVLAGSCTLLLAAIIAIATTCNRRKKEVRKGGALREERPGAAGGGASAPGSPDETARGTGPRPNMFDVLTFPGSGKAPFGSPAADAPPPAVAAAEVPGSEGGSATGESACHFEGQQRLRGAHAEPYSASPGFGKEP-APPVAVWKGHSFNTISGREAEKFSGKDSGKGDSDFNDSDSDISGDALKKDLINHMQSGLWACTAECKILGHSDRCWSPSCAGP-NTHPPPHPPAQMSTFCKSTSLPRDPLRRDNYYQAQLPKTVGLQSVYEKVLHRDYDRTVTLLSPPRPGRLPDLQEIGVPLYESPPGGRYVSPKKGTNENV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O95206-1", "uniprot_id": "PCDH8_HUMAN", "id": "O95206-1", "name": "Protocadherin-8", "aln": "MSPVRRWGSPCLFPLQLFSLCWVLSVAQSKTVRYSTFEEDAPGTVIGTLAEDLHMKVSG--DTSFRLMKQFNSSLLRVREGDGQLTVGDAGLDRERLCGQAPQCVLAFDVVSFSQEQFRLVHVEVEVRDVNDHAPRFPRAQIPVEVSEGAAVGTRIPLEVPVDEDVGANGLQTVRLAEPHSPFRVELQTRADGAQCADLVLLQELDRESQAAYSLELVAQDGGRPPRSATAALSVRVLDANDHSPAFPQGAVAEVELAEDAPVGSLLLDLDAADPDEGPNGDVVFAFGARTPPEARRLFRLDPRSGRLTLAGPVDYERQDTYELDVRAQDRGPGPRAATCKVIVRIRDVNDNAPDIAITPLAAPGAPATSPFAAAAAAAALGGADASSPAGAGTPEAGATSLVPEGAARESLVALVSTSDRDSGANGQVRCALYGHEHFRLQPAYAGSYLVVTAASLDRERIAEYNLTLVAEDRGAPPLRTVRPYTVRVGDENDNAPLFTRPVYEVSVRENNPPGAYLATVAARDRDLGRNGQVTYRLLEAEVGRAGGAVSTYVSVDPATGAIYALRSFDYETLRQLDVRIQASDGGSPQLSSSALVQVRVLDQNDHAPVLVHPAPANGSLEVAVPGRTAKDTVVARVQARDADEGANGELAFELQQQEPREAFAIGRRTGEILLTGDLSQEPPGRVFRALLVISDGGRPPLTTTATVSFVVTAGGGRGPAAPASAGSPERSRPPGSRLGVSGSVLQWDTPLIVIIVLAGSCTLLLAAIIAIATTCNRRKKEVRKGGALREERPGAAGGGASAPGSPEEAARGAGPRPNMFDVLTFPGTGKAPFGSPAADAPPPAVAAAEVPGSEGGSATGESACHFEGQQRLRGAHAEPYGASPGFGKEP-APPVAVWKGHSFNTISGREAEKFSGKDSGKGDSDFNDSDSDISGDALKKDLINHMQSGLWACTAECKILGHSDRCWSPSCSGP-NAHPSPHPPAQMSTFCKSTSLPRDPLRRDNYYQAQLPKTVGLQSVYEKVLHRDYDRTVTLLSPPRPGRLPDLQEIGVPLYQSPPG-RYLSPKKGANENV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1P773-1", "uniprot_id": "A0A8M1P773_DANRE", "id": "A0A8M1P773-1", "name": "Protocadherin-8", "aln": "---MKIYWS-------FFMVSCITSSVFCTTTKYFTFEEDATGTEIGNLSQDLKIDPSEDPETSFKFIQTSN-SIIDMRQMDGLLTVGEV-IDREKLCQRSPQCLITFDVVAFSKEKFQLIHVEIEVKDINDHSPQFTRNETHLDISEDAPLNSRFPLDVAVDHDVGDNYIQSYHISH-NSHFVVEVSTREDGEKSAELVLIKSLDRETEDFYTIEVTATDGGAPQKSGSTTLYIRVLDFNDNSPTFEH-SSLKVELSEDSPIGSRVLKVHAFDPDAGINGEIVYGFVEGSPSEVTRVFQIDLISGEVTLKDIVDYETKKSYELHIQASDLGANSVSSTCRAIVDIIDVNDNAPEIIIKPMTS------------------------TSDG--------VAFITEAAAEESFVALISTSDKDSGPNGYVRTSLEGHEHFKLQQAYSDTFMIITTTTLDRESISEYNLTVISEDLGTPPFKTVKHYTIRITDENDNPPLFSKSIYDVSVIENNIPGSYMTTVVARDLDAGKNGKVSYSLVESKAP-DGSSISTFVSVDPHSGSLYTLRSFDFETLKDVQFSVKATDKGFPSLSSTTLIQVRVVDDNDNFPYFTYPVLRNNSAEIPIPMNANAGYLALKVAAKDEDSGINSELNYHILEDEAK-LFSIDKNTGEIILKRKLTAS-CGEILQIYVSVVDGAREPLSSSANIRFIVTDTGAQEDQIVVLLRAED------------DETFEFDLWSILVISFAGGCVLLLTAIIILTVSCTIKRRRRSFG------RDALYG---STPLSKNNPAG-----PSIY-------SGPNGFLRSEGDSMQPCLYE-------------DKSLSFEEKLFLP---CKPFEQT------------FLWQDEKYCLQRSGTTDQLSVKDSGKGDSDFNDSDSDSSGGAQKPGLTTFQP------LARGSFCSSSDWKIKPCVIQTRNLHAPPGSSYTLG-------FSRTPLYSHSHCSSHMWRDGAGGTLNTQRPLQTFR-SGTLPSYTAHQMRRAVMEIQE-QNEDLQDTLMINAAAEVATTF", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : * :* :. : * . ..*.:* ******.** **.*::**::. * :***:::: * *:: :*: ** ****:. :***:** :***:::****:**:*:*:*:***:**:*:***:*:*.* : :::**.*.:.:*:**:*.**.*** * :*: :::. :* * **:.** ** :.*:***::.****:: *::*:.* *** * :*.:::* :**** **:**:* : : :***:**:*:** :*.:.* *** * **::*: * :*.*. ::*::* **.:** . **** :.:***.::*.* *... ::**:.** * *******:* *.*::: :. * .:::.*.**.**:***:****:***.** ** :* *****:** **:.:::::*:::**** *:*****:::** *:**::**: **:*: *****.*:*::.:*:*** *** **:*::**.*** * *:**:*:* *:*::. * ::**:***** :*::*:*****:***::::. ::*:* * *.***.:*:****:*:**: * :.:*. *.* *:.:* .: . . :: *:* *.* *.** :.: ::*.: *:*.:.****:*. .*: . *.::: : : **.* **:::*.: *:** *. . : : . :::* *::* :**.*.***:*** ::.:*. :::. * * . * *:* * ::.* *.:: :* * . .*: *.: :.: ** : * .:*: : :*:...: . ::::* **************** **.* * .* .. *. .: . ** .*. . * *..* .. :. :.* ** ..: .::: : . :: : : : : ** * . : ** :. . :.. ..", "identical_positions": 373, "similar_positions": 352, "identity": "34.7%" }, { "cls_id": "homologset.agr.MGI:1306801", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZK96-1", "uniprot_id": "A0A8I5ZK96_RAT", "id": "A0A8I5ZK96-1", "name": "", "aln": "------MDLRDFYLLAALIACLRLDSAIAQELIYTIREELPENVPIGNIPKDLNISHINAATGTSASLVYR---------------LVSKAGDAPLVKVSSSTGEIFTTSNRIDREK--------------------------LCAGASYAEE---NECFFELEVVILPN---DFFRLIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYELLNG--------------------------------------------------------------------------------------------------QSVFGLDIVETPEGEKWPQLIVQQN-----------LDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQRSLDREETAIHKVTVLASDGSSTPARATVTINVTDVNDNPPNIDLRYIISPINGTVYLSE--KDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYLLETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSGKNAD--IVYQLGPNASFFDLDRKTGVLTASRVFNREEQE-----RFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDEDAGENKAVTLSILNDNENFVLDPYSG---VIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPGSVVAEVFAVDIDTGMNAELKYTIVSGNNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKALHTLVLVFLYVN-----DTAGNASYIYDLIRRTMETP------------------------------------------LDRNIGDSGQPYQNEDYLTIMIAIVAG------AMVVIVVIFVTVLVRCRHASRFKAAQRSKQGAEWMSPNQENKQNKKKKRKKRKSPKSSLLNFVTIEESKP---DDAVHEPINGTISLPAELEEQSIGRFDWGPAPPTTFKPNSPDLAKHYKSASPQPAFHLKPDTPVSVKKHHVIQELPLDN---------------------------TFVGGCDTLSKRSSTSSDHFSASECSSQGG-------FKTKGPLHTRQCNSHSKNDLIPVTHQKCPSSTGFH-----IRENEESHSESQRRVTFHLPDGSQESCSDSG-LGDHEPVGSGTLISHPLPLVQPQDEFYDQASPDKRTEADGNSDPNSDGPLGPRGLAEATEMCTQECLVLGHSDNCWMPPGLGPYQHPKSPLSTFAPQKEWIKKDKLVNGHTLTRAWKEDTNRNQFNDRKQYGSNEGHFSNGSHMADIPLANLKSY-----KQAGGTIESPKEHQL----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F8VPK8-1", "uniprot_id": "F8VPK8_MOUSE", "id": "F8VPK8-1", "name": "", "aln": "------MDLRDFYLLAALIACLRLDSAIAQELIYTIREELPENVPIGNIPKDLNISHINAATGTSASLVYR---------------LVSKAGDAPLVKVSSSTGEIFTTSNRIDREK--------------------------LCAGASYAEE---NECFFELEVVILPN---DFFRLIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYELLNG--------------------------------------------------------------------------------------------------QSVFGLDIVETPEGEKWPQLIVQQN-----------LDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQRSLDREETAIHKVTVLASDGSSTPARATVTINVTDVNDNPPNIDLRYIISPINGTVYLSE--KDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYLLETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSGKNAD--IVYQLGPNASFFDLDRKTGVLTASRVFNREEQE-----RFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDEDAGENKAVTLSILNDNENFVLDPYSG---VIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPGSVVAEVFAVDIDTGMNAELKYTIVSGNNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKALHTLVLVFLYVN-----DTAGNTSYIYDLIRRTMETP------------------------------------------LDRNIGDSGQPYQNEDYLTIMIAIVAG------AMVVIVVIFVTVLVRCRHASRFKAAQRSKQGAEWMSPNQENKQNKKKKRKKRKSPKSSLLNFVTIEESKP---DDAVHEPINGTISLPAELEEQGIGRFDWGPAPPTTFKPNSPDLAKHYKSASPQPAFHLKPDTPVSVKKHHVIQELPLDN---------------------------TFVGGCDTLSKRSSTSSDHFSASECSSQGG-------FKTKGPLHTRQCNSYSKNDNIPVTHQKCPGSTSFH-----IRENEESHSESQRRVTFHLPDGSQESCSDSG-LGDHEPVGSGTLISHPLPLVQPQDEFYDQASPDKRTEADGNSDPNSDGPLGPRGLAEATEMCTQECLVLGHSDNCWMPPGLGPYQHPKSPLSTFAPQKEWIKKDKLVNGHTLTRAWKEDTNRNQFNDRKQYGSNEGHFNNGGHMADIPLANLKSY-----KQAGGTIESPKEHQL----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HC56-1", "uniprot_id": "PCDH9_HUMAN", "id": "Q9HC56-1", "name": "Protocadherin-9", "aln": "------MDLRDFYLLAALIACLRLDSAIAQELIYTIREELPENVPIGNIPKDLNISHINAATGTSASLVYR---------------LVSKAGDAPLVKVSSSTGEIFTTSNRIDREK--------------------------LCAGASYAEE---NECFFELEVVILPN---DFFRLIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYELLNG--------------------------------------------------------------------------------------------------QSVFGLDIVETPEGEKWPQLIVQQN-----------LDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQRSLDREETAIHKVTVLASDGSSTPARATVTINVTDVNDNPPNIDLRYIISPINGTVYLSE--KDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYLLETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSGKNAD--IVYQLGPNASFFDLDRKTGVLTASRVFDREEQE-----RFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDADAGENKAVTLSILNDNDNFVLDPYSG---VIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVSGNNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKSLHTLVLVFLYVN-----DTAGNASYIYDLIRRTMETP------------------------------------------LDRNIGDSSQPYQNEDYLTIMIAIIAG------AMVVIVVIFVTVLVRCRHASRFKAAQRSKQGAEWMSPNQENKQNKKKKRKKRKSPKSSLLNFVTIEESKP---DDAVHEPINGTISLPAELEEQSIGRFDWGPAPPTTFKPNSPDLAKHYKSASPQPAFHLKPDTPVSVKKHHVIQELPLDN---------------------------TFVGGCDTLSKRSSTSSDHFSASECSSQGG-------FKTKGPLHTRQCNSHSKSDNIPVTPQKCPSSTGFH-----IQENEESHYESQRRVTFHLPDGSQESCSDSG-LGDHEPVGSGTLISHPLPLVQPQDEFYDQASPDKRTEADGNSDPNSDGPLGPRGLAEATEMCTQECLVLGHSDNCWMPPGLGPYQHPKSPLSTFAPQKEWVKKDKLVNGHTLTRAWKEDSNRNQFNDRKQYGSNEGHFNNGSHMTDIPLANLKSY-----KQAGGATESPKEHQL----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q24298-1", "uniprot_id": "CADE_DROME", "id": "Q24298-1", "name": "DE-cadherin", "aln": "MSTSVQRMSRSYHCINMSATPQAGHLNPAQQQTHQQHKRKCRDLGRRLIPARLLLGVIVAISLLSPALALHSPPDKNFSGDNRKPAFKNCAGYAPKVKEEQPENTYVLTVEAVDPDPDQVIRYSIVQSPFERPKFFINPSTGVIFTTHTFDRDEPIHEKFVFVTVQATDNGLPPLDDVCTFNVTIEDINDNAPAFNKARYDESMSENAQPDAVVMTISASDFDDGNNSLVEYEILRERDFQYFKIDKESGIIYLKRPIDKRPGQSYAIIVRAYNVVPDPPQDAQIEVRIRVVESSIKPPSFVNPIDTPIYLKENLKNFTHPIATLRAVSNMPDKPEVIFELNTGRTEQTNSKNTFVFNQIGNEVTISLGKTLDYEAITDYTLTMIVRN--THELGTEHQIKIQVEDVNDNIPYYTEVKSGT-ILENEPPGTPVMQVRAFDMDG---TSANNIVSFELADNRE-YFTIDPNTGNITALTTFDREERDFYNVKVIASDNSPSSLFDNGEPNRGHQVFRISIGDKNDHKPHFQQDKYLAERLLEDANTNTEVIEVKAEDEDNASQILYSIESGNVGDAFKIGLKTGKITVNQKLDYETITEYELKVRAFDG---IYDDYTTVVIKIEDVNDNPPVFKQDYSVTILEETTYDDCILTVEAYDPDIKDRNADQHIVYSIHQNDGNRWTIDNSGCLRLVKTLDRDPPNGHKNWQVLIKANDEDGVGTTVSTVKEVTVTLKDINDNAP-FLINEMPVYWQENRNPGHVVQLQANDYDDTPGAGNFTFGIDSEATPDIKTKFSMDGDYLHANVQFDREAQKEYFIPIRISDSGVPRQSAVSILHLVIGDVNDN---AMSEGSSRIFIYNYKGEAPETDIGRVFVDDLDD-WDLEDKYFEWKDLPHDQFRLNPSTGMITMLVHTAEGEYDLSFVVTEDSMFVPRHSVDAYVTVVVRELPEEAVDKSGSIRFINVTKEEFISVPRDFQSPDALSLKDRLQLSLAKLFNTSVSNVDVFTVLQNENHTLDVRFSAHGSPYYAPEKLNGIVAQNQQRLENELDLQMLMVNIDECLIEKFKCEESCTNELHKSSVPYMIYSNTTSFVGVNAFVQAQCVCEAPLMRRCLNGGSPRYGENDVCDCIDGFTGPHCELVSVAFYGSGYAFYEPIAACNNTKISLEITPQIDQGLIMYLGPLNFNPLLAISDFLALELDNGYPVLTVDYGSGAIRIRHQHIKMVADRTYQLDIILQRTSIEMTVDNCRLSTCQTLGAPIGPNEFLNVNAPLQLGGTPVDLEQLGRQLNWTHVPNQKGFFGCIRNLTINEQTYNLGMPSVFRNIDSGCQQSVAVAFSFGIDRNFIIAIIVCLALLLIILLAVVVQKKQKNGWHEKDIDDIRETIINYEDEGGGERDTDYDLNVLRTQPFYEEKLYKDPHALQGNMRDPNDIPDIADFLGDKKENCDRDVGATTVDDVRHYAYEGDGNSDGSLSSLASCTDDGDLNFDYLSNFGPRFRKLADMYGEEPSDTDSNVDDDQGWRI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.:: : : . **: : ::. .:: ** * :. * * : *.:*. : : . ** ** ** ... . . * : :* : : : :: .: :* *. : * * : : .::: ::* ***** * .. : *:.**: :: . **:* * * *.: .**:*. : :* *: .* : :. ::.:* ** * *.:.: *.: * : .: ::: *.***** * :.* : . * ** * **.*:*::* * * :. . *.. ::* : *::: .** **. ::**** :::*.*:***.*.:. . * . . . * . . :: **:* : .**: :* *. :* * .::: ** . : : : ... **** .*:.:*: * *. :: : * :*:** *****:*:* :.*.. . **. : : ..:*** ***.: * . ::* * :.::*: : :.::... .*. ..:.: * **: * ***:* * *.: .: .** .* : : *: .*:.* .: : :* :::**.**** *..* : :: :*.* * :*:.: : : : ***** .:* *. * . * : :..**. *:* : * ** .. :. **::* ** **: :.* : .* :*.: * : :::.: * *.: *.:*. :* .. :..* ** .:. ..** : *. ::* : :::* : *:. :... : : *... :* .: .. : : :. .: * :: ..* :: * : *:* . .** . .: .:. * : *: : . . ::* * . .: : * *** *: . . . : *: * *.: *. ::.:.**: :. :. : *....*. : **::: . * :: .*.*:* : : :* .. . . ::. .* *: . :: . : * * :. :: .* .* : * : : . . * . :. ::: ..* .: : : :* .: ::. : ... . : . . *: : *..: * *. *.*.: : ", "identical_positions": 252, "similar_positions": 434, "identity": "16.56%" }, { "cls_id": "homologset.agr.MGI:1306802", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35671-1", "uniprot_id": "ITBP1_MOUSE", "id": "O35671-1", "name": "Integrin beta-1-binding protein 1", "aln": "MFRKGKKRHSSSSSQSSEISTKSKSVDSSLGGLSRSSTVASLDTDSTKSSGQSNSNLDTCAEFRIKYVGAIEKLAVSEGKSLEGPLDLINYIDVAQQDGKLPFVPLEEEFILGVSKYGIKVSTTDQHGVLHRHALYLIIRMVCYDDGLGAGKSLLALKTTDASNEEYSLWVYQCNSLEQAQAICKVLSTAFDSVLTSDKS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14713-1", "uniprot_id": "ITBP1_HUMAN", "id": "O14713-1", "name": "Integrin beta-1-binding protein 1", "aln": "MFRKGKKRHSSSSSQSSEISTKSKSVDSSLGGLSRSSTVASLDTDSTKSSGQSNNNSDTCAEFRIKYVGAIEKLKLSEGKGLEGPLDLINYIDVAQQDGKLPFVPPEEEFIMGVSKYGIKVSTSDQYDVLHRHALYLIIRMVCYDDGLGAGKSLLALKTTDASNEEYSLWVYQCNSLEQAQAICKVLSTAFDSVLTSEKP", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******************************************************.* ***************** :****.************************ *****:***********:**:.*********************************************************************:*.", "identical_positions": 188, "similar_positions": 9, "identity": "94.0%" }, { "cls_id": "homologset.agr.MGI:1306803", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZDG6-1", "uniprot_id": "D3ZDG6_RAT", "id": "D3ZDG6-1", "name": "", "aln": "MYWKHESAAPALPEGCRLPAEGGPTTDQVMAQPGSGCKATTRCLEGTAPPAMAQSDAEALAGALDKDEGRASPCTPSTPSVCSPPSAASSVPSAGKNICSSCGLEILDRYLLKVNNLIWHVRCLECSVCRTSLRQQNSCYIKNKEIYCKMDYFSRFGTKCARCGRQIYASDWVRRARGNAYHLACFACFSCKRQLSTGEEFGLVEEKVLCRIHYDTMIENLKRAAENGNGLTLEGAVPSEQDSQPK-PAKRARTSFTAEQLQVMQAQFAQDNNPDAQTLQKLADMTGLSRRVIQVWFQNCRARHKKHTPQHPVPPSGAPPSRLPSSLSDDIHYSPFSSPERARMVTLHGYIESQVQCGQVHCRLPYTAPPVHLKADMDGPLSSRGEKVILFQY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R1R0-1", "uniprot_id": "LHX6_MOUSE", "id": "Q9R1R0-1", "name": "LIM/homeobox protein Lhx6", "aln": "-----------------------------MAQPGSGCKATTRCLEGTAPPAMAQSDAEALAGALDKDEGRASPCTPSTPSVCSPPSAASSVPSAGKNICSSCGLEILDRYLLKVNNLIWHVRCLECSVCRTSLRQQNSCYIKNKEIYCKMDYFSRFGTKCARCGRQIYASDWVRRARGNAYHLACFACFSCKRQLSTGEEFGLVEEKVLCRIHYDTMIENLKRAAENGNGLTLEGAVPSEQDSQPK-PAKRARTSFTAEQLQVMQAQFAQDNNPDAQTLQKLADMTGLSRRVIQVWFQNCRARHKKHTPQHPVPPSGAPPTRLPSALSDDIHYSPFSSPERARMVTLHGYIESQVQCGQVHCRLPYTAPPVHLKADLDGPLSSRGEKVILFQY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UPM6-1", "uniprot_id": "LHX6_HUMAN", "id": "Q9UPM6-1", "name": "LIM/homeobox protein Lhx6", "aln": "-----------------------------MAQPGSGCKATTRCLEGTAPPAMAQSDAEALAGALDKDEGQASPCTPSTPSVCSPPSAASSVPSAGKNICSSCGLEILDRYLLKVNNLIWHVRCLECSVCRTSLRQQNSCYIKNKEIFCKMDYFSRFGTKCARCGRQIYASDWVRRARGNAYHLACFACFSCKRQLSTGEEFGLVEEKVLCRIHYDTMIENLKRAAENGNGLTLEGAVPSEQDSQPK-PAKRARTSFTAEQLQVMQAQFAQDNNPDAQTLQKLADMTGLSRRVIQVWFQNCRARHKKHTPQHPVPPSGAPPSRLPSALSDDIHYTPFSSPERARMVTLHGYIESQVQCGQVHCRLPYTAPPVHLKADMDGPLSNRGEKVILFQY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8IRC7-1", "uniprot_id": "AWH_DROME", "id": "Q8IRC7-1", "name": "LIM/homeobox protein Awh", "aln": "----------------------------------------------------------------MKTELRS---------------------------CAACGEPISDRFFLEVGGCSWHAHCLRCCMCMCPLDRQQSCFIRERQVYCKADYSKNFGAKCSKCCRGISASDWVRRARELVFHLACFACDQCGRQLSTGEQFALMDDRVLCKAHYLETVEGGTTSSDEG----------CDGDGYHKSKTKRVRTTFTEEQLQVLQANFQIDSNPDGQDLERIASVTGLSKRVTQVWFQNSRARQKKHIHAGKNKIREPEGSSFARHINLQLTYS------------FQNNAQNPMHLNGSKAGLYPTHESSMDELSQDSSVHCMPSEV-----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * :: *::** * **::*:*.. **.:**.*.:* .* :*:**:*::::::** ** ..**:**::* * * ********* .:******* .* *******:*.*::::***: ** :*. . ::::* .: *. * :**.**:** *****:**:* *.***.* *:::*.:****:** ******.***:*** . : :. :. :: *: ::. :. :: . :. * * . : . *..: .:* ", "identical_positions": 111, "similar_positions": 91, "identity": "28.24%" }, { "cls_id": "homologset.agr.MGI:1306805", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q03404-1", "uniprot_id": "TFF2_MOUSE", "id": "Q03404-1", "name": "Trefoil factor 2", "aln": "MGPRGAPLLAVVLVLGLHALVEGEKPSPCRCSRLTPHNRKNCGFPGITSEQCFDLGCCFDSSVAGVPWCFHPLPNQESEQCVMEVSARKNCGYPGISPEDCASRNCCFSNLIFEVPWCFFPQSVEDCHY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q09030-1", "uniprot_id": "TFF2_RAT", "id": "Q09030-1", "name": "Trefoil factor 2", "aln": "MGPRGAPLLVVVLVLGLHALAEGEKPSPCRCSRMTPSNRKNCGFPGITSDQCFNLGCCFDSSVAGVPWCFHPLPNQASEQCVMEVSARENCGYPGISPEDCASRHCCFSNLIFEVPWCFFPQSVDDCHY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q03403-1", "uniprot_id": "TFF2_HUMAN", "id": "Q03403-1", "name": "Trefoil factor 2", "aln": "MGRRDAQLLAALLVLGLCALAGSEKPSPCQCSRLSPHNRTNCGFPGITSDQCFDNGCCFDSSVTGVPWCFHPLPKQESDQCVMEVSDRRNCGYPGISPEECASRKCCFSNFIFEVPWCFFPKSVEDCHY", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** *.* **..:***** **. .******:***::* **.*********:***: ********:**********:* *:******* *.**********:****:*****:**********:**:****", "identical_positions": 100, "similar_positions": 21, "identity": "77.52%" }, { "cls_id": "homologset.agr.MGI:1306806", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P33261-1", "uniprot_id": "CP2CJ_HUMAN", "id": "P33261-1", "name": "Cytochrome P450 2C19", "aln": "----------------------MDPFVVLVLCLSCLLLLSIWRQS--SGRGKLPPGPTPLPVIGNILQIDIKDVSKS-----LTNLSKIYG-PVFTLYFGLERMVVLHGYEVVKEALIDLGEEFSGRGHFPLAERANR-GFGIVFSNGKRWKEIRRFSLMTLRNFGM-----GKRSIEDRVQEEARCLVEELRKTKASPCDPTFILG------------CAPCNVICSIIFQKRFDYK-DQQFLNLMEKLNENIRIVSTP-WIQICNNFPTIIDYFPGTHNKLLKNLAFMESDILEKVKEHQESMDINNP---RDFIDCFLIKMEKEKQN------QQSEFTIENLVITAADLLGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRS---PCMQDRGHMPYTDAVVHEVQRYIDLIPTSLPHAVTCDVKFRNYLIPKGTTILTSLTSVLHDNKEFPNPEMFDPRHFLDEGGN-FKKSNYFMPFSAGKRICVGEGLARMELFLFLTFILQNFNLKSLIDPKDLDTTPVVNGFASVPPFYQLCFIPV------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P11712-1", "uniprot_id": "CP2C9_HUMAN", "id": "P11712-1", "name": "Cytochrome P450 2C9", "aln": "----------------------MDSLVVLVLCLSCLLLLSLWRQS--SGRGKLPPGPTPLPVIGNILQIGIKDISKS-----LTNLSKVYG-PVFTLYFGLKPIVVLHGYEAVKEALIDLGEEFSGRGIFPLAERANR-GFGIVFSNGKKWKEIRRFSLMTLRNFGM-----GKRSIEDRVQEEARCLVEELRKTKASPCDPTFILG------------CAPCNVICSIIFHKRFDYK-DQQFLNLMEKLNENIKILSSP-WIQICNNFSPIIDYFPGTHNKLLKNVAFMKSYILEKVKEHQESMDMNNP---QDFIDCFLMKMEKEKHN------QPSEFTIESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRS---PCMQDRSHMPYTDAVVHEVQRYIDLLPTSLPHAVTCDIKFRNYLIPKGTTILISLTSVLHDNKEFPNPEMFDPHHFLDEGGN-FKKSKYFMPFSAGKRICVGEALAGMELFLFLTSILQNFNLKSLVDPKNLDTTPVVNGFASVPPFYQLCFIPV------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P33260-1", "uniprot_id": "CP2CI_HUMAN", "id": "P33260-1", "name": "Cytochrome P450 2C18", "aln": "----------------------MDPAVALVLCLSCLFLLSLWRQS--SGRGRLPSGPTPLPIIGNILQLDVKDMSKS-----LTNFSKVYG-PVFTVYFGLKPIVVLHGYEAVKEALIDHGEEFSGRGSFPVAEKVNK-GLGILFSNGKRWKEIRRFCLMTLRNFGM-----GKRSIEDRVQEEARCLVEELRKTNASPCDPTFILG------------CAPCNVICSVIFHDRFDYK-DQRFLNLMEKFNENLRILSSP-WIQVCNNFPALIDYLPGSHNKIAENFAYIKSYVLERIKEHQESLDMNSA---RDFIDCFLIKMEQEKHN------QQSEFTVESLIATVTDMFGAGTETTSTTLRYGLLLLLKYPEVTAKVQEEIECVVGRNRS---PCMQDRSHMPYTDAVVHEIQRYIDLLPTNLPHAVTCDVKFKNYLIPKGTTIITSLTSVLHNDKEFPNPEMFDPGHFLDKSGN-FKKSDYFMPFSAGKRMCMGEGLARMELFLFLTTILQNFNLKSQVDPKDIDITPIANAFGRVPPLYQLCFIPV------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P10632-1", "uniprot_id": "CP2C8_HUMAN", "id": "P10632-1", "name": "Cytochrome P450 2C8", "aln": "----------------------MEPFVVLVLCLSFMLLFSLWRQS--CRRRKLPPGPTPLPIIGNMLQIDVKDICKS-----FTNFSKVYG-PVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITK-GLGIISSNGKRWKEIRRFSLTTLRNFGM-----GKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILG------------CAPCNVICSVVFQKRFDYK-DQNFLTLMKRFNENFRILNSP-WIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVNNP---RDFIDCFLIKMEQEKDN------QKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRS---PCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGN-FKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLKSVDDLKNLNTTAVTKGIVSLPPSYQICFIPV------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P56654-1", "uniprot_id": "CP237_MOUSE", "id": "P56654-1", "name": "Cytochrome P450 2C37", "aln": "----------------------MDPILVLVLTLSCLFLLSLWRQS--SERGKLPPGPTPLPIIGNILQIDVKDICQS-----FTNLSKVYG-PVYTLYLGRKPTVVLHGYEAVKEALVDHGEEFAGRGRFPVFDKATN-GMGLAFSKGNVWKNTRRFSLMTLRNLGM-----GKRSIEDRVQEEARCLVEELRKTNGSPCDPTFILG------------CAPCNVICSIIFQDRFDYK-DRDFLNLMEKLNEITKILSSP-WLQICNTYPALLDYCPGSHKQFFKNYASIKNFLLEKIKEHEESLDVTIP---RDFIDYFLINGGQEDGN------QPLQNRLEHLAITVTDLFSAGTETTSTTLRYAILLLLKYPHVTAKVQEEIEHVIGKHRS---PCMQDRSRMPYTDAMIHEVQRFIDLIPNSLPHEVTSDIKFRNYFIPKGTTVITSLSSVLHDSTEFPNPEKFDPGHFLDENGK-FKKSDYFIPFSTGKRICAGEGLARMELFLFLTSILQNFNLKPLVHPKDIDVTPMLIGLASVPPAFQLCFIPS------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q95078-1", "uniprot_id": "CP18A_DROME", "id": "Q95078-1", "name": "Cytochrome P450 18a1", "aln": "MLADSYLIKFVLRQLQVQQDGDAQHLLMVFLGLLALVTLLQWLVRNYRELRKLPPGPWGLPVIGYLLFMGSEKHTR------FMELAKQYG-SLFSTRLGSQLTVVMSDYKMIRECFRR--EEFTGRPDTPFMQTLN--GYGIINSTGKLWKDQRRFLHDKLRQFGMTYMGNGKQQMQKRIMTEVHEFIGHLHASDGQPVDMSPVIS------------VAVSNVICSLMMSTRFSID-DPKFRRFNFLIEEGMRLFGEI-HTVDYIPTMQCFPSISTAKNKIAQNRAEMQRFYQDVIDDHKRSFDPNNI---RDLVDFYLCEIEKAKAEGTDAELFDGKNHEEQLVQVIIDLFSAGMETIKTTLLWINVFMLRNPKEMRRVQDELDQVVGRHRL---PTIEDLQYLPITESTILESMRRSSIVPLATTHSPTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTEGK-VRKPEYFIPFGVGRRMCLGDVLARMELFLFFASFMHCFDIALPEG-QPLPSLKGNVGATITPESFKVCLKRRPLGPTAADPHHMRNVGAN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VW43-1", "uniprot_id": "CP305_DROME", "id": "Q9VW43-1", "name": "Probable cytochrome P450 305a1", "aln": "----------------------MSALIFLCAILIGFVIYSLISSA--RRPKNFPPGPRFVPWLGNTLQFRKEASAVGGQHILFERWAKDFRSDLVGLKLGREYVVVALGHEMVKEVQLQEVFEGRPDNFFLRLRTMGT-RKGITCTDGQLWYEHRHFAMKQMRNVGY-----GRSQMEHHIELEAEELLGQLERTEEQPIEPVTWLA------------QSVLNVLWCLIAGKRIARQEDGTLRRLLDLMNRRSKLFDICGGLLAQFPWLRHVAPDRTGYNLIQQLNTELYGFFMDTIEEHRRQLAKDPSPAESDLIYAYLQEMKDRSAGG-----ESSTFNETQLVMTILDFFIAGSQTTSNTINLALMVLAMRPDVQEKLFSQVTASVAAASTDAFPHLSRREAFDYMDAFIMEVQRFFHITPITGPRRALWATKLGGYDIPKNATILISLRSVHLDKEHWKDPLEFRPERFIDSAGK-CFKDEYFMPFGMGRRRCLGDALARACIFSFLVRIVQHFSVVLPAG--ESPSMVLLPGITLTPKPYKVQFVKRT-----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VG17-1", "uniprot_id": "CP304_DROME", "id": "Q9VG17-1", "name": "Probable cytochrome P450 304a1", "aln": "----------------------MITETLLTICAAVFLCLSYRYAVG--RPSGFPPGPPKIPLFGSYLFMLIINFKYLHK--AALTLSRWYKSDIIGLHVGPFPVAVVHSADGVREILNNQVFDGRPQLFVAAMRDPGQDVRGIFFQDGPLWKEQRRFILRYLRDFGFG---RRFDQLELVIQEQLNDMLDLIRNGPKYPHEHEMVKSGGYRVLLPLLFNPFSANAHFYIVYNECLSREEMGKLVKLCQMGIQFQRNADDYGKMLSIIPWIRHIWPEWSGYNKLNESNLFVRQFFADFVDKYLDSYEEGVE---RNFMDVYIAEMRRGPGYG---------FNRDQLIMGLVDFSFPAFTAIGVQLSLLVQYLMLYPAVLRRVQNEIDEVVGCGRL---PNLEDRKNLPFTEATIREGLRIETLVPSDVPHKALEDTELLGYRIPKDTIVVPSLYAFHSDARIWSDPEQFRPERFLDADGKLCLKLDVSLPFGAGKRLCAGETFARNMLFLVTATMCQHFDFVLGPNDRLPDLSQNLNGLIISPPDFWLQLQDRH-----------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :. :*.** :* :* * : :: : : .* .* . . ::* : *: * * : *:* :*:.* .:: : : . :: :. * : . *. :: : . : : . : . . : . : : :..: . ::: :: : * *: .. : : : * :: .:: :. * :. : :: : * * : * .: :: .* ** .: :: : :. : : .* * * :*:* *: * . :**. *:* * *: :* :* . . : : *.. . * : : : ", "identical_positions": 45, "similar_positions": 118, "identity": "7.88%" }, { "cls_id": "homologset.agr.MGI:1306812", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AN75-1", "uniprot_id": "A0A8I6AN75_RAT", "id": "A0A8I6AN75-1", "name": "Zinc finger protein 239", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDEKPYKCDKCGKGFTRSSSLLVHHSVHTGEKPFKCDRCGKGFSQSSKLHIHQRVHTGEKPYECEECGMSFSQRSNLHIHQRVHTGERPYKCGECGKGFSQSSNLHIHRCTHTGEKPYQCYECGKGFSQSSDLRIHLRVHTGEKPYHCGKCGKGFSQSSKLLIHQRVHTGEKPYECSRCGKGFSQSSNLHIHQRVHRKDLH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P24399-1", "uniprot_id": "ZN239_MOUSE", "id": "P24399-1", "name": "Zinc finger protein 239", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAEKPYKCDKCGKGFTRSSSLLVHHSVHTGEKPFKCDRCGKGFSQSSKLHIHKRVHTGEKPYACEECGMSFSQRSNLHIHQRVHTGERPYKCGECGKGFSQSSNLHIHRCTHTGEKPYQCYECGKGFSQSSDLRIHLRVHTGEKPYHCGKCGQGFSQSSKLLIHQRVHTGEKPYECSKCGKGFSQSSNLHIHQRVHRKELH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q16600-1", "uniprot_id": "ZN239_HUMAN", "id": "Q16600-1", "name": "Zinc finger protein 239", "aln": "MASTITGSQDCIVNHRGEVDGEPELDISPCQQWGEASSPISRNRDSVMTLQSGCFENIESETYLPLKVSSQIDTQDSSVKFCKNEPQDHQESRRLFVMEESTERKVIKGESCSENLQVKLVSDGQELASPLLNGEATCQNGQLKESLDPIDCNCKDIHGWKSQVVSCSQQRAHTEEKPCDHNNCGKILNTSPDGHPYEKIHTAEKQYECSQCGKNFSQSSELLLHQRDHTEEKPYKCEQCGKGFTRSSSLLIHQAVHTDEKPYKCDKCGKGFTRSSSLLIHHAVHTGEKPYKCDKCGKGFSQSSKLHIHQRVHTGEKPYECEECGMSFSQRSNLHIHQRVHTGERPYKCGECGKGFSQSSNLHIHRCIHTGEKPYQCYECGKGFSQSSDLRIHLRVHTGEKPYHCGKCGKGFSQSSKLLIHQRVHTGEKPYECSKCGKGFSQSSNLHIHQRVHKKDPR", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ********************:**:*******:***:**************:********* *********************************************** *****************************************:************************:******************:*: :", "identical_positions": 186, "similar_positions": 10, "identity": "40.61%" }, { "cls_id": "homologset.agr.MGI:1306815", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P20814-1", "uniprot_id": "CP2CD_RAT", "id": "P20814-1", "name": "Cytochrome P450 2C13, male-specific", "aln": "----------------------MDPVVVLLLSLFFLLFLSLWRPS--SGRGKLPPGPTPLPIIGNFFQVDMKD-----IRQSLTNFSKTYG-PVYTLYVGSQPTVVLHGYEALKEALVDHGEEFSGRGRLPICEKVAK-GQGIAFSHGNVWKATRHFTVKTLRNLGM-----GKGTIEDKVQEEAKWLVKELKKTNGSPCDPQFIMG------------CAPGNVICSIILQNRFDYE-DKDFLNLIEKVNEAVKIISSPG-IQVFNIFPILLDYCPGNHNIYFKNHTWLKSYLLEKIKEHEESLDVSNP---RDFIDYFLIERNQENAN------QWMNYTLEHLAIMVTDLFFAGIETVSSTMRFALLLLMKYPHVTAKVQEEIDHVIGRHR---SPCMQDRSHMPYTNAMVHEVQRYIDIGPNGLLHEVTCDTKFRNYFIPKGTAVLTSLTSVLHDSKEFPNPEMFDPGHFLDENGN-FKKSDYFIPFSAGKRMCLGESLARMELFLFLTTILQNFKLKSLVDPKDINTTPICSSLSSVPPTFQMRFIPL------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P56657-1", "uniprot_id": "CP240_MOUSE", "id": "P56657-1", "name": "Cytochrome P450 2C40", "aln": "----------------------MDPFVVLVLCLSFLLVLSLWRQR--SARGNLPPGPTPLPIIGNYHLIDMKD-----IGQCLTNFSKTYG-PVFTLYFGSQPIVVLHGYEAIKEALIDHGEEFSGRGRIPVFDKVST-GKGIGFSHGNVWKATRVFTVNTLRNLGM-----GKRTIENKVQEEAQWLMKELKKTNGSPCDPQFIIG------------CAPCNVICSIVFQNRFDYK-DKDFLSLIGKVNECTEILSSPG-CQIFNAVPILIDYCPGSHNKLFKNHTWIKSYLLGKIKEHEESLDVTNP---RDFIDYFLIQRRQKNGI------EHMDYTIEHLATLVTDLVFGGTETLSSTMRFALLLLMKHTHITAKVQEEIDNVIGRHR---SPCMQDRNHMPYTNAMVHEVQRYIDLGPNGVVHEVTCDTKFRNYFIPKGTQVMTSLTSVLHDSTEFPNPEVFDPGHFLDDNGN-FKKSDYFVPFSAGKRICVGESLARMELFLFLTTILQNFKLKPLVDPKDIDMTPKHSGFSKIPPNFQMCFIPVE-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P10632-1", "uniprot_id": "CP2C8_HUMAN", "id": "P10632-1", "name": "Cytochrome P450 2C8", "aln": "----------------------MEPFVVLVLCLSFMLLFSLWRQS--CRRRKLPPGPTPLPIIGNMLQIDVKD-----ICKSFTNFSKVYG-PVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITK-GLGIISSNGKRWKEIRRFSLTTLRNFGM-----GKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILG------------CAPCNVICSVVFQKRFDYK-DQNFLTLMKRFNENFRILNSPW-IQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVNNP---RDFIDCFLIKMEQEKDN------QKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHR---SPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGN-FKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLKSVDDLKNLNTTAVTKGIVSLPPSYQICFIPV------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q95078-1", "uniprot_id": "CP18A_DROME", "id": "Q95078-1", "name": "Cytochrome P450 18a1", "aln": "MLADSYLIKFVLRQLQVQQDGDAQHLLMVFLGLLALVTLLQWLVRNYRELRKLPPGPWGLPVIG-YLLFMGSE-----KHTRFMELAKQYG-SLFSTRLGSQLTVVMSDYKMIRECFRR--EEFTGRPDTPFMQTLN--GYGIINSTGKLWKDQRRFLHDKLRQFGMTYMGNGKQQMQKRIMTEVHEFIGHLHASDGQPVDMSPVIS------------VAVSNVICSLMMSTRFSID-DPKFRRFNFLIEEGMRLFGEIH-TVDYIPTMQCFPSISTAKNKIAQNRAEMQRFYQDVIDDHKRSFDPNNI---RDLVDFYLCEIEKAKAEGTDAELFDGKNHEEQLVQVIIDLFSAGMETIKTTLLWINVFMLRNPKEMRRVQDELDQVVGRHR---LPTIEDLQYLPITESTILESMRRSSIVPLATTHSPTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTEGK-VRKPEYFIPFGVGRRMCLGDVLARMELFLFFASFMHCFDIALPEG-QPLPSLKGNVGATITPESFKVCLKRRPLGPTAADPHHMRNVGAN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VW43-1", "uniprot_id": "CP305_DROME", "id": "Q9VW43-1", "name": "Probable cytochrome P450 305a1", "aln": "----------------------MSALIFLCAILIGFVIYSLISSA--RRPKNFPPGPRFVPWLGNTLQFRKEASAVGGQHILFERWAKDFRSDLVGLKLGREYVVVALGHEMVKEVQLQEVFEGRPDNFFLRLRTMGT-RKGITCTDGQLWYEHRHFAMKQMRNVGY-----GRSQMEHHIELEAEELLGQLERTEEQPIEPVTWLA------------QSVLNVLWCLIAGKRIARQEDGTLRRLLDLMNRRSKLFDICGGLLAQFPWLRHVAPDRTGYNLIQQLNTELYGFFMDTIEEHRRQLAKDPSPAESDLIYAYLQEMKDRSAGG-----ESSTFNETQLVMTILDFFIAGSQTTSNTINLALMVLAMRPDVQEKLFSQVTASVAAASTDAFPHLSRREAFDYMDAFIMEVQRFFHITPITGPRRALWATKLGGYDIPKNATILISLRSVHLDKEHWKDPLEFRPERFIDSAGK-CFKDEYFMPFGMGRRRCLGDALARACIFSFLVRIVQHFSVVLPAG--ESPSMVLLPGITLTPKPYKVQFVKRT-----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VG17-1", "uniprot_id": "CP304_DROME", "id": "Q9VG17-1", "name": "Probable cytochrome P450 304a1", "aln": "----------------------MITETLLTICAAVFLCLSYRYAVG--RPSGFPPGPPKIPLFGSYLFMLIIN--FKYLHKAALTLSRWYKSDIIGLHVGPFPVAVVHSADGVREILNNQVFDGRPQLFVAAMRDPGQDVRGIFFQDGPLWKEQRRFILRYLRDFGFG---RRFDQLELVIQEQLNDMLDLIRNGPKYPHEHEMVKSGGYRVLLPLLFNPFSANAHFYIVYNECLSREEMGKLVKLCQMGIQFQRNADDYGKMLSIIPWIRHIWPEWSGYNKLNESNLFVRQFFADFVDKYLDSYEEGVE---RNFMDVYIAEMRRGPGYG---------FNRDQLIMGLVDFSFPAFTAIGVQLSLLVQYLMLYPAVLRRVQNEIDEVVGCGR---LPNLEDRKNLPFTEATIREGLRIETLVPSDVPHKALEDTELLGYRIPKDTIVVPSLYAFHSDARIWSDPEQFRPERFLDADGKLCLKLDVSLPFGAGKRLCAGETFARNMLFLVTATMCQHFDFVLGPNDRLPDLSQNLNGLIISPPDFWLQLQDRH-----------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: :: :**** :* :* . :: : : .* .* . . ::* : ** * * * * :*:.* :: : : . :: :. * : . *. :: : . : : . . . . * : : :..: . ::: :: : . :* : *: . : : : . :: .:: :. * :. . : :: : * * : * : .:: .* ** .: :: : :. * : .* * * :*:* *: * : :**. *:* * *: :** :* . . : : *.. . . * : : : ", "identical_positions": 48, "similar_positions": 116, "identity": "8.41%" }, { "cls_id": "homologset.agr.MGI:1306818", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P05179-1", "uniprot_id": "CP2C7_RAT", "id": "P05179-1", "name": "Cytochrome P450 2C7", "aln": "MDLVTFLVLTLSSLILLSLWRQSSRRRKLPPGPTPLPIIGNFLQIDVKNISQS-----LTKFSKTYG-PVFTLYLGSQPTVILHGYEAIKEALIDNGEKFSGRGSYPMNENVT-KGFGIVFSNGNRWKEMRRFTIMNFRNLGIGK--RNIEDRVQEEAQCLVEELRKTKGSPCDPSLILN------------CAPCNVICSITFQNHFDYKDKEMLTFMEKVNENLKIMSSPWMQVCNSFPSLIDYFPG--THHKIAKNINYMKSYLLKKIEEHQESLDVTNP---RDFVDYYLIKQK-QANNIEQSEYSHENLTCSIMDLIGAGTETMSTTLRYALLLLMKYPHVTAKVQEEIDRVIGRHRS---PCMQDRKHMPYTDAMIHEVQRFINFVPTNLPHAVTCDIKFRNYLIPKGTKVLTSLTSVLHDSKEFPNPEMFDPGHFLDENGN-FKKSDYFLPFSAGKRACVGEGLARMQLFLFLTTILQNFNLKSLVHPKDIDTMPVLNGFASLPPTYQLCFIPS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P56656-1", "uniprot_id": "CP239_MOUSE", "id": "P56656-1", "name": "Cytochrome P450 2C39", "aln": "MDLVTFLVLTLSSLILLSLWRQSCGRGSLPPGPTPFPIIGNFLQIDIKNVSQS-----LTNFSKAYG-PVFTLYLGSRPTVVLHGYEAVKEALIDHGEEFSDRGSIPMVEKIN-NGLGIVFSNGNRWKEIRRFTLTTLRNLGMGK--RNIEDRVQEEAQCLVEELRKTKGSPCDPTFILS------------CAPCNVICSIIFQDRFDYKDKDFLMLMEKLNENVKILSSPWLQVCNNFPLLIDYCPG--SHHKVLKNVKYIRSYLLEKIKEHQESLDVTNP---RDFIDYYLIKQK-QANHIQQAEFSLENLACTINNLFAAGTETTSTTLRYALLLLMKYPDVTAKVQEEIDHVIGRHRS---PCMQDRNHMPYTDAMIHEVQRFINLVPNNIPRAVTCDIKFRNYLIPKGTTVVTSLTSVLHDSKEFPNPELFDPGHFLDANGN-FKKSDHFMPFSAGKRVCAGEGLARMELFLFLTTILQNFKLKSLVHPKDIDMIPFVNGLIALPPHYQVCIIPR-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P33261-1", "uniprot_id": "CP2CJ_HUMAN", "id": "P33261-1", "name": "Cytochrome P450 2C19", "aln": "MDPFVVLVLCLSCLLLLSIWRQSSGRGKLPPGPTPLPVIGNILQIDIKDVSKS-----LTNLSKIYG-PVFTLYFGLERMVVLHGYEVVKEALIDLGEEFSGRGHFPLAERAN-RGFGIVFSNGKRWKEIRRFSLMTLRNFGMGK--RSIEDRVQEEARCLVEELRKTKASPCDPTFILG------------CAPCNVICSIIFQKRFDYKDQQFLNLMEKLNENIRIVSTPWIQICNNFPTIIDYFPG--THNKLLKNLAFMESDILEKVKEHQESMDINNP---RDFIDCFLIKME-KEKQNQQSEFTIENLVITAADLLGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRS---PCMQDRGHMPYTDAVVHEVQRYIDLIPTSLPHAVTCDVKFRNYLIPKGTTILTSLTSVLHDNKEFPNPEMFDPRHFLDEGGN-FKKSNYFMPFSAGKRICVGEGLARMELFLFLTFILQNFNLKSLIDPKDLDTTPVVNGFASVPPFYQLCFIPV-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P11712-1", "uniprot_id": "CP2C9_HUMAN", "id": "P11712-1", "name": "Cytochrome P450 2C9", "aln": "MDSLVVLVLCLSCLLLLSLWRQSSGRGKLPPGPTPLPVIGNILQIGIKDISKS-----LTNLSKVYG-PVFTLYFGLKPIVVLHGYEAVKEALIDLGEEFSGRGIFPLAERAN-RGFGIVFSNGKKWKEIRRFSLMTLRNFGMGK--RSIEDRVQEEARCLVEELRKTKASPCDPTFILG------------CAPCNVICSIIFHKRFDYKDQQFLNLMEKLNENIKILSSPWIQICNNFSPIIDYFPG--THNKLLKNVAFMKSYILEKVKEHQESMDMNNP---QDFIDCFLMKME-KEKHNQPSEFTIESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRS---PCMQDRSHMPYTDAVVHEVQRYIDLLPTSLPHAVTCDIKFRNYLIPKGTTILISLTSVLHDNKEFPNPEMFDPHHFLDEGGN-FKKSKYFMPFSAGKRICVGEALAGMELFLFLTSILQNFNLKSLVDPKNLDTTPVVNGFASVPPFYQLCFIPV-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P33260-1", "uniprot_id": "CP2CI_HUMAN", "id": "P33260-1", "name": "Cytochrome P450 2C18", "aln": "MDPAVALVLCLSCLFLLSLWRQSSGRGRLPSGPTPLPIIGNILQLDVKDMSKS-----LTNFSKVYG-PVFTVYFGLKPIVVLHGYEAVKEALIDHGEEFSGRGSFPVAEKVN-KGLGILFSNGKRWKEIRRFCLMTLRNFGMGK--RSIEDRVQEEARCLVEELRKTNASPCDPTFILG------------CAPCNVICSVIFHDRFDYKDQRFLNLMEKFNENLRILSSPWIQVCNNFPALIDYLPG--SHNKIAENFAYIKSYVLERIKEHQESLDMNSA---RDFIDCFLIKME-QEKHNQQSEFTVESLIATVTDMFGAGTETTSTTLRYGLLLLLKYPEVTAKVQEEIECVVGRNRS---PCMQDRSHMPYTDAVVHEIQRYIDLLPTNLPHAVTCDVKFKNYLIPKGTTIITSLTSVLHNDKEFPNPEMFDPGHFLDKSGN-FKKSDYFMPFSAGKRMCMGEGLARMELFLFLTTILQNFNLKSQVDPKDIDITPIANAFGRVPPLYQLCFIPV-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VW43-1", "uniprot_id": "CP305_DROME", "id": "Q9VW43-1", "name": "Probable cytochrome P450 305a1", "aln": "MSALIFLCAILIGFVIYSLISSARRPKNFPPGPRFVPWLGNTLQFRKEASAVGGQHILFERWAKDFRSDLVGLKLGREYVVVALGHEMVKEVQLQEVFEGRPDNFFLRLRTMG-TRKGITCTDGQLWYEHRHFAMKQMRNVGYGR--SQMEHHIELEAEELLGQLERTEEQPIEPVTWLA------------QSVLNVLWCLIAGKRIARQEDGTLRRLLDLMNRRSKLFDICGGLLAQFPWLRHVAPDRTGYNLIQQLNTELYGFFMDTIEEHRRQLAKDPSPAESDLIYAYLQEMKDRSAGGESSTFNETQLVMTILDFFIAGSQTTSNTINLALMVLAMRPDVQEKLFSQVTASVAAASTDAFPHLSRREAFDYMDAFIMEVQRFFHITPITGPRRALWATKLGGYDIPKNATILISLRSVHLDKEHWKDPLEFRPERFIDSAGK-CFKDEYFMPFGMGRRRCLGDALARACIFSFLVRIVQHFSVVLPAG--ESPSMVLLPGITLTPKPYKVQFVKRT", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VG17-1", "uniprot_id": "CP304_DROME", "id": "Q9VG17-1", "name": "Probable cytochrome P450 304a1", "aln": "MITETLLTICAAVFLCLSYRYAVGRPSGFPPGPPKIPLFGSYLFMLIINFKYLHK--AALTLSRWYKSDIIGLHVGPFPVAVVHSADGVREILNNQVFDGRPQLFVAAMRDPGQDVRGIFFQDGPLWKEQRRFILRYLRDFGFGRRFDQLELVIQEQLNDMLDLIRNGPKYPHEHEMVKSGGYRVLLPLLFNPFSANAHFYIVYNECLSREEMGKLVKLCQMGIQFQRNADDYGKMLSIIPWIRHIWPEWSGYNKLNESNLFVRQFFADFVDKYLDSYEEGVER---NFMDVYIAEMR----RGPGYGFNRDQLIMGLVDFSFPAFTAIGVQLSLLVQYLMLYPAVLRRVQNEIDEVVGCGRL---PNLEDRKNLPFTEATIREGLRIETLVPSDVPHKALEDTELLGYRIPKDTIVVPSLYAFHSDARIWSDPEQFRPERFLDADGKLCLKLDVSLPFGAGKRLCAGETFARNMLFLVTATMCQHFDFVLGPNDRLPDLSQNLNGLIISPPDFWLQLQDRH", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * :. * :*.** .* :*. * : :: : :. : .* .: . : ::* : . . ** :* * * *:* : :*:.* *: .:* :: : . :: :.. * : *. : . : :: * : .. . : :. : . * :: : : : . . :.:: . ::: :: : . :. .* :: .. : . : : * * * :: .:: :. * :. * : : :* : * * : * *: . :: .* ***.: :: ** :. : . : :* * * :*:* *: * . :**. *:* * *: :* :* . . : *:*.. .: * : : : ", "identical_positions": 61, "similar_positions": 138, "identity": "11.69%" }, { "cls_id": "homologset.agr.MGI:1306819", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P05179-1", "uniprot_id": "CP2C7_RAT", "id": "P05179-1", "name": "Cytochrome P450 2C7", "aln": "MDLVTFLVLTLSSLILLSLWRQSSRRRKLPPGPTPLPIIGN---FLQID--VKNISQSLTKFSKTYG-PVFTLYLGSQPTVILHGYEAIKEALIDNGEKFSGRGSYPMNENVTKG---FGIVFSNGNRWKEMRRFTIMNFRNLGIGK--RNIEDRVQEEAQCLVEELRKTKGSPCDPSLILN------------CAPCNVICSITFQNHFDYKDKEMLTFMEKVNENLKIMSSPWMQVCNSFPSLIDYFPGT--HHKIAKNINYMKSYLLKKIEEHQESLDVT---NPRDFVDYYLIKQK-QANNIEQSEYSHENLTCSIMDLIGAGTETMSTTLRYALLLLMKYPHVTAKVQEEIDRVIGRH---RSPCMQDRKHMPYTDAMIHEVQRFINFVPTNLPHAVTCDIKFRNYLIPKGTKVLTSLTSVLHDSKEFPNPEMFDPGHFLDENGNFK-KSDYFLPFSAGKRACVGEGLARMQLFLFLTTILQNFNLKSLVHPKDIDTMPVLNGFASLPPTYQLCFIPS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P56655-1", "uniprot_id": "CP238_MOUSE", "id": "P56655-1", "name": "Cytochrome P450 2C38", "aln": "MDLVTFLVLTLSSLILLSLWRQRSRRGRLPPGPTPFPIIGN---FLQID--VKNFNQSLTNFSKTYG-PVFTLYLGSRPIVVLHGYEAVKEALIDHGEEFSGRENIPMSEKINNG---LGITFSNGNSWKETRRFTLMTLRNLGMGK--RNIEDRVREEAQCLVEELRKTKGSPCDPTFILS------------CAPCNVICSIIFQDRFDYKDKDFLMLMKKLNENVKILSSPWLQVCNNFPLLIDYCPGS--HHKVLKNFKYIRSYLLEKVKEHQESLDVT---NPRDFIDYFLIKQK-QANHIEQAEYSLENLVCTINNLFAAGTETTSTTLRYALLLLMKYPDVTAKVQEEIDHVVGRH---RSPCMQDRSRMPYTDAMIHEVQRFINLVPNNLPHAVTCDIKFRNYIIPKGTTVVTSLTSVLHDSKEFPNPEMFDPGHFLDANGNFK-KSDYFMTFSAGKRVCAGEGLARMELFLILTTILQNFKLKSLVHPKDIDMIPFVNGLITLPPHYQLCFIPL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P33261-1", "uniprot_id": "CP2CJ_HUMAN", "id": "P33261-1", "name": "Cytochrome P450 2C19", "aln": "MDPFVVLVLCLSCLLLLSIWRQSSGRGKLPPGPTPLPVIGN---ILQID--IKDVSKSLTNLSKIYG-PVFTLYFGLERMVVLHGYEVVKEALIDLGEEFSGRGHFPLAERANRG---FGIVFSNGKRWKEIRRFSLMTLRNFGMGK--RSIEDRVQEEARCLVEELRKTKASPCDPTFILG------------CAPCNVICSIIFQKRFDYKDQQFLNLMEKLNENIRIVSTPWIQICNNFPTIIDYFPGT--HNKLLKNLAFMESDILEKVKEHQESMDIN---NPRDFIDCFLIKME-KEKQNQQSEFTIENLVITAADLLGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRN---RSPCMQDRGHMPYTDAVVHEVQRYIDLIPTSLPHAVTCDVKFRNYLIPKGTTILTSLTSVLHDNKEFPNPEMFDPRHFLDEGGNFK-KSNYFMPFSAGKRICVGEGLARMELFLFLTFILQNFNLKSLIDPKDLDTTPVVNGFASVPPFYQLCFIPV-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P11712-1", "uniprot_id": "CP2C9_HUMAN", "id": "P11712-1", "name": "Cytochrome P450 2C9", "aln": "MDSLVVLVLCLSCLLLLSLWRQSSGRGKLPPGPTPLPVIGN---ILQIG--IKDISKSLTNLSKVYG-PVFTLYFGLKPIVVLHGYEAVKEALIDLGEEFSGRGIFPLAERANRG---FGIVFSNGKKWKEIRRFSLMTLRNFGMGK--RSIEDRVQEEARCLVEELRKTKASPCDPTFILG------------CAPCNVICSIIFHKRFDYKDQQFLNLMEKLNENIKILSSPWIQICNNFSPIIDYFPGT--HNKLLKNVAFMKSYILEKVKEHQESMDMN---NPQDFIDCFLMKME-KEKHNQPSEFTIESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRN---RSPCMQDRSHMPYTDAVVHEVQRYIDLLPTSLPHAVTCDIKFRNYLIPKGTTILISLTSVLHDNKEFPNPEMFDPHHFLDEGGNFK-KSKYFMPFSAGKRICVGEALAGMELFLFLTSILQNFNLKSLVDPKNLDTTPVVNGFASVPPFYQLCFIPV-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P33260-1", "uniprot_id": "CP2CI_HUMAN", "id": "P33260-1", "name": "Cytochrome P450 2C18", "aln": "MDPAVALVLCLSCLFLLSLWRQSSGRGRLPSGPTPLPIIGN---ILQLD--VKDMSKSLTNFSKVYG-PVFTVYFGLKPIVVLHGYEAVKEALIDHGEEFSGRGSFPVAEKVNKG---LGILFSNGKRWKEIRRFCLMTLRNFGMGK--RSIEDRVQEEARCLVEELRKTNASPCDPTFILG------------CAPCNVICSVIFHDRFDYKDQRFLNLMEKFNENLRILSSPWIQVCNNFPALIDYLPGS--HNKIAENFAYIKSYVLERIKEHQESLDMN---SARDFIDCFLIKME-QEKHNQQSEFTVESLIATVTDMFGAGTETTSTTLRYGLLLLLKYPEVTAKVQEEIECVVGRN---RSPCMQDRSHMPYTDAVVHEIQRYIDLLPTNLPHAVTCDVKFKNYLIPKGTTIITSLTSVLHNDKEFPNPEMFDPGHFLDKSGNFK-KSDYFMPFSAGKRMCMGEGLARMELFLFLTTILQNFNLKSQVDPKDIDITPIANAFGRVPPLYQLCFIPV-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VG17-1", "uniprot_id": "CP304_DROME", "id": "Q9VG17-1", "name": "Probable cytochrome P450 304a1", "aln": "MITETLLTICAAVFLCLSYRYAVGRPSGFPPGPPKIPLFGSYLFMLIIN--FKYLHKAALTLSRWYKSDIIGLHVGPFPVAVVHSADGVREILNN--QVFDGRPQLFVAAMRDPGQDVRGIFFQDGPLWKEQRRFILRYLRDFGFGRRFDQLELVIQEQLNDMLDLIRNGPKYPHEHEMVKSGGYRVLLPLLFNPFSANAHFYIVYNECLSREEMGKLVKLCQMGIQFQRNADDYGKMLSIIPWIRHIWPEWSGYNKLNESNLFVRQFFADFVDKYLDSYEEG---VERNFMDVYIAEMR-RGPGYG---FNRDQLIMGLVDFSFPAFTAIGVQLSLLVQYLMLYPAVLRRVQNEIDEVVGCG---RLPNLEDRKNLPFTEATIREGLRIETLVPSDVPHKALEDTELLGYRIPKDTIVVPSLYAFHSDARIWSDPEQFRPERFLDADGKLCLKLDVSLPFGAGKRLCAGETFARNMLFLVTATMCQHFDFVLGPNDRLPDLSQNLNGLIISPPDFWLQLQDRH", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VW43-1", "uniprot_id": "CP305_DROME", "id": "Q9VW43-1", "name": "Probable cytochrome P450 305a1", "aln": "MSALIFLCAILIGFVIYSLISSARRPKNFPPGPRFVPWLGNTLQFRKEASAVGGQHILFERWAKDFRSDLVGLKLGREYVVVALGHEMVKEVQLQ--EVFEGRPDNFFLRLRTMG-TRKGITCTDGQLWYEHRHFAMKQMRNVGYGR--SQMEHHIELEAEELLGQLERTEEQPIEPVTWLA------------QSVLNVLWCLIAGKRIARQEDGTLRRLLDLMNRRSKLFDICGGLLAQFPWLRHVAPDRTGYNLIQQLNTELYGFFMDTIEEHRRQLAKDPSPAESDLIYAYLQEMKDRSAGGESSTFNETQLVMTILDFFIAGSQTTSNTINLALMVLAMRPDVQEKLFSQVTASVAAASTDAFPHLSRREAFDYMDAFIMEVQRFFHITPITGPRRALWATKLGGYDIPKNATILISLRSVHLDKEHWKDPLEFRPERFIDSAGKCF-KDEYFMPFGMGRRRCLGDALARACIFSFLVRIVQHFSVVLPAGES--PSMVLLPGITLTPKPYKVQFVKRT", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * :. * :*.** .* :*. : . :: : :. : .* .: . : ::* : : *.** . * ** :* * * *:* : :*:.* *: .:* :. : . :: :.. * : *. : . : :: * : .. . : :. : . * :: : : : . . :.:: . ::: :: : . : :. .* :: .. : . : : * * * :: .:: :. * :. * : : :* : * * : * *: . :: .* ***.: :: ** :. : . : :* * * :*:* *: * . :.*. *:* * *: :* :* . . : *:*.. .: * : : : ", "identical_positions": 63, "similar_positions": 142, "identity": "12.02%" }, { "cls_id": "homologset.agr.MGI:1306821", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A3M8-1", "uniprot_id": "D4A3M8_RAT", "id": "D4A3M8-1", "name": "Cytoplasmic protein", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------MTEEVIVIAKWDYTAQQDQELDIRKNERLWLLDDSKTWWRVRNAANRTGYVPSNYVERKNSLKKGSLVKNLKDTLGLGKTRRKPSARDASPTPSTDAEYPANGS-------GADRIYDLNIPAFVKFAYVAEREDELSLVKGSRVTVMEKCSDGWWRGSFNGQIGWFPSNYVLEEADEAAAE------APSFLSLRRG--TALSNGQ----GARVLHVVQTLYPFSSVTEEELSFEKGETMEVIEKPENDPEWWKCKNARGQVGLVPKNYVVVLSDGP---------------------------------ALHPTH-TPQISYTGPSASGRFAGREWYYGNVTRHQAECALNERGVEGDFLIRDSESSPSDFSVSLKASGRNKHFKVQLVDSVYCIGQRRFHSMDELVEHYKKAPIFTSEHGEKLYLVRALQ-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O55033-1", "uniprot_id": "NCK2_MOUSE", "id": "O55033-1", "name": "Cytoplasmic protein NCK2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------MTEEVIVIAKWDYTAQQDQELDIRKNERLWLLDDSKTWWRVRNAANRTGYVPSNYVERKNSLKKGSLVKNLKDTLGLGKTRRKPSARDASPTPSTDAEYPANGS-------GADRIYDLNIPAFVKFAYVAEREDELSLVKGSRVTVMEKCSDGWWRGSFNGQIGWFPSNYVLEEADEAAAE------APSFLSLRRG--TALSNGQ----GARVLHVVQTLYPFSSVTEEELSFEKGETMEVIEKPENDPEWWKCKNARGQVGLVPKNYVVVLSDGP---------------------------------ALHPAH-TPQISYTGPSASGRFAGREWYYGNVTRHQAECALNERGVEGDFLIRDSESSPSDFSVSLKASGRNKHFKVQLVDSVYCIGQRRFHSMDELVEHYKKAPIFTSEHGEKLYLVRALQ-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43639-1", "uniprot_id": "NCK2_HUMAN", "id": "O43639-1", "name": "Cytoplasmic protein NCK2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------MTEEVIVIAKWDYTAQQDQELDIKKNERLWLLDDSKTWWRVRNAANRTGYVPSNYVERKNSLKKGSLVKNLKDTLGLGKTRRKTSARDASPTPSTDAEYPANGS-------GADRIYDLNIPAFVKFAYVAEREDELSLVKGSRVTVMEKCSDGWWRGSYNGQIGWFPSNYVLEEVDEAAAE------SPSFLSLRKG--ASLSNGQ----GSRVLHVVQTLYPFSSVTEEELNFEKGETMEVIEKPENDPEWWKCKNARGQVGLVPKNYVVVLSDGP---------------------------------ALHPAH-APQISYTGPSSSGRFAGREWYYGNVTRHQAECALNERGVEGDFLIRDSESSPSDFSVSLKASGKNKHFKVQLVDNVYCIGQRRFHTMDELVEHYKKAPIFTSEHGEKLYLVRALQ-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q4I8-1", "uniprot_id": "A0A8M9Q4I8_DANRE", "id": "A0A8M9Q4I8-1", "name": "Cytoplasmic protein", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------MTEEVIVIAKWDYTAQQDQELDIRKNERLWLLDDSKTWWRVRNASNRTGYVPSNYVERKNSLKKTSLVKNLKDTLGLGKTKRKTSARDPSPTPSTEAEYPSNGSAGGGGGGGAERIYDLNIPALVKFSYAAERDDELNLVKGERVVVMEKCSDGWWRGSHAGRVGWFPSNYVQEEVGYTDNDGVFGDTVGGFRSLKVGQGSAMANGRPGGSGSSVLHVVQTLYPFSSVTEEELNFEKGETMEVLEKPENDPEWWRCKNSRGIVGLVPKNYVVVLDDGPVA------------------------------KGLGSSHGSPHISHTVPSRVGKFAGKGWYYGNVTRHHAECALNERGVEGDFLIRDSESSPSDFSISLKAVGKNKHFKVQHQDGVYCIGQRRFSSMDELVEHYKKAPIFTSEQGDKLYLVKALG-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IPW2-2", "uniprot_id": "NCK_DROME", "id": "Q8IPW2-2", "name": "SH2/SH3 adapter protein dreadlocks", "aln": "MLEHPQRFVRNIPDSSASSQQYPQQQQHPPQLPQHQNLNLNQNQNLNQNQIYQYRPQVPVPVPGSPAHHQRHSSLSQQQQLHHHRTLSTASSCSAQHKSVTFGQPALDCGGNGSGSANGSGSGNSSSGSAAGNAGTQSMAGNMKHGKSQDDVCYVVAKYDYAAQGAQELDLRKNERYLLLDDSKHWWRVQNSRNQSGYVPSNYVKKEKPSLFDSIKKKVKKGSGS-KTLPNCSPSRQVESPTMSRRLPPDPA-------------EAIGTAVVKYNYQAQQPDELSLTKGTRILILEKSNDGWWRGQSGNSVGWFPSNYTTEDCDNDGE----------IHTYAMA--------------ENVLDIVVALYSFTSNNDQELSFEKGDRLEIVDRPASDPDWYKARNNQGQVGLVPRNYLQELNDYLATPYRNASASAGNGNGGGSNGGAGGGGGNDSMERRNEGNKPAAQSSGQPIERPNLAGKSWYYGAITRSQCDTVLNGHGHDGDFLIRDSETNMGDYSVSLKAPGRNKHFRVHVEQNMYCIGQRKFHSLDQLVDHYQRAPIYTNKQGEKLYLVRSLPKANGT", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *:**:**:** ****::**** ****** ****:*: *::********::::. *: *::*. * ** : *. :*: . . *.: : : .*.**: * *:: ***.*.** *: ::**..******. . :*******. *: . : : . **.:* :**.*:* .::**.****: :*::::* .**:*::.:* :* *****:**: *.* : .. * * .:**: **** :** :.: .** :* :*********:. .*:*:**** *:****:*: :.:******:* ::*:**:**::***:*.::*:*****::* ", "identical_positions": 158, "similar_positions": 113, "identity": "26.96%" }, { "cls_id": "homologset.agr.MGI:1306822", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZAC5-1", "uniprot_id": "D3ZAC5_RAT", "id": "D3ZAC5-1", "name": "", "aln": "MVDYYEVLGVPRQASAEAIRKAYRKLALKWHPDKNPEHKEEAERRFKQVAQAYEVLSDARKREVYDRCG---------------------EVGEVGGGGAAGS------------------------------------PFHDAFQ-----------------------------------------YVFSFRDPAEVFREFFGGHDPFSFDFFG-DPLEN-----FFGDRRSTRGSRSRGSVPFSTSFTEFPGFGG--------GFASLDTGFTSFGSPGNSGLSSFSMSCGGGAAGNYKSVSTSTEIINGKKITTKRIVENGQERVEVEEDGELKSLIINGKEQLLRIDTQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35723-1", "uniprot_id": "DNJB3_MOUSE", "id": "O35723-1", "name": "DnaJ homolog subfamily B member 3", "aln": "MVDYYEVLGVPRQASAEAIRKAYRKLALKWHPDKNPEHKEEAERRFKQVAQAYEVLSDVRKREVYDRCG---------------------EVGEVGGGGAAGS------------------------------------PFHDAFQ-----------------------------------------YVFSFRDPAEVFREFFGGHDPFSFDFFGGDPLEN-----FFGDRRSTRGSRSRGAVPFSTSFTEFPGFGG--------GFASLDTGFTSFGSPGNSGLSSFSMSCGGGAAGNYKSVSTSTEIINGKKITTKRIVENGQERVEVEEDGELKSLIINGREQLLRINTQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WWF6-1", "uniprot_id": "DNJB3_HUMAN", "id": "Q8WWF6-1", "name": "DnaJ homolog subfamily B member 3", "aln": "MVDYYEVLDVPRQASSEAIKKAYRKLALKWHPDKNPENKEEAERRFKQVAEAYEVLSDAKKRDIYDRYG---------------------EAGAEGG-CTGGR------------------------------------PFEDPFE-----------------------------------------YVFSFRDPADVFREFFGGQDPFSFDLLG-NPLEN-----ILGGSEELLGKQKQ----------------------------SVCTPFLCLQ---------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A8DYF7-1", "uniprot_id": "A8DYF7_DROME", "id": "A8DYF7-1", "name": "", "aln": "MVDYYKILDVSRSATDSEVKKAYRKLALKWHPDKNPDNLDEANKRFRELSEAYEVLSDARKRRIYDARATLHKSSNSGSSSSNSSSYTRYRNGGTGGSSSYGRDYDYDYYPGSGYGSGSGRRSGNRYQAFTFRNIFEGTPFHKMFEKKRRIYDEYGKDGLGDRGQSRSHARHHYSTHDFDDFDILGGFQFAFRPPEEVFREFFGIHSPFADLFRDANGHSNGSTSGSSGSRRNGGSSGSSRHHHHHHQHKVASPFGAPMLNYSMMDFFMPTSGFTSFSSMTHGNGSSGVTHISSGPGASVKRTSTSTVFVNGKKLMTKRVVENGKETVFSYENDVLKSKTVMGSLQ-------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*****::*.*.*.*: . ::****************:: :**::**:::::*******.:** :** . . * ** : * **.. *: : *:** * :******* :.**: : . : .* *. .. .. . : * .: ", "identical_positions": 63, "similar_positions": 47, "identity": "17.85%" }, { "cls_id": "homologset.agr.MGI:1306823", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K283-1", "uniprot_id": "A0A0G2K283_RAT", "id": "A0A0G2K283-1", "name": "ATP-dependent RNA helicase DHX8", "aln": "MAVAVATAGVLMGSEPGPAEELAKLEYLSLVSKVCTELDNHLGINDKDLAEFVISLAEKNTTFDTFKASLVKNGAEFTDSLISNLLRLIQTMRPPAKPSTSKD--PVVKPKTEKEKLKELFPVLCQPDNPSVRTMLDEEDVKVAVD------------------VLKELEALMPSAAGQE---KQRDTEHRDRTKKKKRSRSRDRDRDRDRDRDRDRDRDRD--KDRERDRDRERDRERDRDRDHKRRHRSR-SRSHSRTRE-RAKGKSRYRSRSRSQSPFKDRK---DREKYGERNLDRWRDKHVDRPPP-----EEPAIGDIYNGKVTSIMQFGCFVQLEGLRKR-WEGLVHISELRREGRVANVADVVSKGQRVKVKVLSFTG-TKTSLSMKDVDQETGEDLNPNRRRNLVGETNEETSMRNPDRP-----THLSLVSAPEVEDDSLERKRLTRISDPEKWEIKQMIAANVLSKEEFPDFDEETGI-------------------------LPKVDDEEDEDLEIELVEEE-PPFLRG-HTKQSMDMSPIKIVKNPDGSLSQAAMMQSALAKERRELKQAQREAEMDSIPMGLNKHWVDPLPDAEGRQIAANMRGIGMMPNDIPEWKKHAFGGNKASYGKKTQMSILEQRESLPIYKLKEQLVQAVHDNQILIVIGETGSGKTTQITQYLAEAGYTSRGKIGCTQPRRVAAMSVAKRVSEEFGCCLGQEVGYTIRFEDCTSPETVIKYMTDGMLLRECLIDPDLTQYAIIMLDEAHERTIHTDVLFGLLKKTVQKRQDMKLIVTSATLDAVKFSQYFYEAPIFTIPGRTYPVEILYTKEPETDYLDASLITVMQIHLTEPPGDILVFLTGQEEIDTACEILYERMKSLGPDVPELIILPVYSALPSEMQTRIFDPAPPGSRKVVIATNIAETSLTIDGIYYVVDPGFVKQKVYNSKTGIDQLVVTPISQVWAQAKQRAGRAGRTGPGKCYRLYTERAYRDEMLTTNVPEIQRTNLASTVLSLKAMGINDLLSFDFMDAPPMETLITAMEQLYTLGALDDEGLLTRLGRRMAEFPLEPMLCKMLIMSVHLGCSEEMLTIVSMLSVQNVFYRPKDKQALADQKKAKFHQTEGDHLTLLAVYNSWKNNKFSNPWCYENFIQARSLRRAQDIRKQMLGIMDRHKLDVVSCGKSTVRVQKAICSGFFRNAAKKDPQEGYRTLIDQQVVYIHPSSALFNRQPEWVVYHELVLTTKEYMREVTTIDPRWLVEFAPAFFKVSDPTKLSKQKKQQRLEPLYNRYE-EPNAWRISRAFRRR--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2A4P0-1", "uniprot_id": "DHX8_MOUSE", "id": "A2A4P0-1", "name": "ATP-dependent RNA helicase DHX8", "aln": "MAVAVAAAGVLMGSEPGPAEELAKLEYLSLVSKVCTELDNHLGINDKDLAEFVISLAEKNTTFDTFKASLVKNGAEFTDSLISNLLRLIQTMRPPAKPSTSKD--PVVKPKTEKEKLRELFPVLCQPDNPSARTMLDEEDVKVAVD------------------VLKELEALMPSAAGQE---KQRDPEHRDRTKKKKRSRSRDRDRDRDRDRDRDRDRDRDRDKDRERDRDRERDRERDRERDHKRRHRSR-SRSHSRTRE-RTKGKSRYRSRSRSQSPFKDRK---DREKYGERNLDRWRDKHVDRPPP-----EEPAIGDIYNGKVTSIMQFGCFVQLEGLRKR-WEGLVHISELRREGRVANVADVVSKGQRVKVKVLSFTG-TKTSLSMKDVDQETGEDLNPNRRRNLVGETNEETSMRNPDRP-----THLSLVSAPEVEDDSLERKRLTRISDPEKWEIKQMIAANVLSKEEFPDFDEETGI-------------------------LPKVDDEEDEDLEIELVEEE-PPFLRG-HTKQSMDMSPIKIVKNPDGSLSQAAMMQSALAKERRELKQAQREAEMDSIPMGLNKHWVDPLPDAEGRQIAANMRGIGMMPNDIPEWKKHAFGGNKASYGKKTQMSILEQRESLPIYKLKEQLVQAVHDNQILIVIGETGSGKTTQITQYLAEAGYTSRGKIGCTQPRRVAAMSVAKRVSEEFGCCLGQEVGYTIRFEDCTSPETVIKYMTDGMLLRECLIDPDLTQYAIIMLDEAHERTIHTDVLFGLLKKTVQKRQDMKLIVTSATLDAVKFSQYFYEAPIFTIPGRTYPVEILYTKEPETDYLDASLITVMQIHLTEPPGDILVFLTGQEEIDTACEILYERMKSLGPDVPELIILPVYSALPSEMQTRIFDPAPPGSRKVVIATNIAETSLTIDGIYYVVDPGFVKQKVYNSKTGIDQLVVTPISQ--AQAKQRAGRAGRTGPGKCYRLYTERAYRDEMLTTNVPEIQRTNLASTVLSLKAMGINDLLSFDFMDAPPMETLITAMEQLYTLGALDDEGLLTRLGRRMAEFPLEPMLCKMLIMSVHLGCSEEMLTIVSMLSVQNVFYRPKDKQALADQKKAKFHQTEGDHLTLLAVYNSWKNNKFSNPWCYENFIQARSLRRAQDIRKQMLGIMDRHKLDVVSCGKSTVRVQKAICSGFFRNAAKKDPQEGYRTLIDQQVVYIHPSSALFNRQPEWVVYHELVLTTKEYMREVTTIDPRWLVEFAPAFFKVSDPTKLSKQKKQQRLEPLYNRYE-EPNAWRISRAFRRR--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14562-1", "uniprot_id": "DHX8_HUMAN", "id": "Q14562-1", "name": "ATP-dependent RNA helicase DHX8", "aln": "MAVAVAMAGALIGSEPGPAEELAKLEYLSLVSKVCTELDNHLGINDKDLAEFVISLAEKNTTFDTFKASLVKNGAEFTDSLISNLLRLIQTMRPPAKPSTSKD--PVVKPKTEKEKLKELFPVLCQPDNPSVRTMLDEDDVKVAVD------------------VLKELEALMPSAAGQE---KQRDAEHRDRTKKKKRSRSRDRNRDRDRDR------------------------ERNRDRDHKRRHRSR-SRSRSRTRE-RNKVKSRYRSRSRSQSPPKDRK---DRDKYGERNLDRWRDKHVDRPPP-----EEPTIGDIYNGKVTSIMQFGCFVQLEGLRKR-WEGLVHISELRREGRVANVADVVSKGQRVKVKVLSFTG-TKTSLSMKDVDQETGEDLNPNRRRNLVGETNEETSMRNPDRP-----THLSLVSAPEVEDDSLERKRLTRISDPEKWEIKQMIAANVLSKEEFPDFDEETGI-------------------------LPKVDDEEDEDLEIELVEEE-PPFLRG-HTKQSMDMSPIKIVKNPDGSLSQAAMMQSALAKERRELKQAQREAEMDSIPMGLNKHWVDPLPDAEGRQIAANMRGIGMMPNDIPEWKKHAFGGNKASYGKKTQMSILEQRESLPIYKLKEQLVQAVHDNQILIVIGETGSGKTTQITQYLAEAGYTSRGKIGCTQPRRVAAMSVAKRVSEEFGCCLGQEVGYTIRFEDCTSPETVIKYMTDGMLLRECLIDPDLTQYAIIMLDEAHERTIHTDVLFGLLKKTVQKRQDMKLIVTSATLDAVKFSQYFYEAPIFTIPGRTYPVEILYTKEPETDYLDASLITVMQIHLTEPPGDILVFLTGQEEIDTACEILYERMKSLGPDVPELIILPVYSALPSEMQTRIFDPAPPGSRKVVIATNIAETSLTIDGIYYVVDPGFVKQKVYNSKTGIDQLVVTPISQ--AQAKQRAGRAGRTGPGKCYRLYTERAYRDEMLTTNVPEIQRTNLASTVLSLKAMGINDLLSFDFMDAPPMETLITAMEQLYTLGALDDEGLLTRLGRRMAEFPLEPMLCKMLIMSVHLGCSEEMLTIVSMLSVQNVFYRPKDKQALADQKKAKFHQTEGDHLTLLAVYNSWKNNKFSNPWCYENFIQARSLRRAQDIRKQMLGIMDRHKLDVVSCGKSTVRVQKAICSGFFRNAAKKDPQEGYRTLIDQQVVYIHPSSALFNRQPEWVVYHELVLTTKEYMREVTTIDPRWLVEFAPAFFKVSDPTKLSKQKKQQRLEPLYNRYE-EPNAWRISRAFRRR--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q925-1", "uniprot_id": "A0A8M9Q925_DANRE", "id": "A0A8M9Q925-1", "name": "ATP-dependent RNA helicase DHX8", "aln": "------------MAEIG-EDELKKLEYLSLVSKVCTELDNHLGINDKDLAEFVISLAEKNTAFDGFKSALVKNGADFTDSLIGNLLRLIQTMRPPAKASTSKASFPAVKPKNEKDKLKELFPALCRPDNPTTRNMLDEDDVKVAAD------------------AMKELEMFMPSVSGTEPSSSKHRSETSSSSRKKRRSRSRSRDRDRDRDRDR----------------------ERDRDRDRRRRHRSR-SRSRSRSNE-RDRRKRRSRWHSRSRSRSPART---DRDKGS----DRWKDKHVDRPPP-----EEPSVADIYNGKVTSIMQFGCFVQLEGLRKR-WEGLVHISELRREGRVANVADVVSKGQRVKVKVLSFTG-SKTSLSMKDVDQDTGEDLNPNRRRNVGGEGQEESAMRNPDRP-----TNLNLGHAPEVEDDTLERKRLTKISDPEKWEIKQMIAANVLSKEEFPDFDEETGI-------------------------LPKVDDEEDEDLEIELVEEE-PPFLRG-HTKQSMDMSPVKIVKNPDGSLSQAAMMQSALAKERREVKQAQREAEMDSIPMGLNKHWVDPLPDVDGRQIAANMRGIGMMPNDIPEWKKHAFGGNKASYGKKTQLSILEQRESLPIYKLKEQLIQAVHDNQILIVIGETGSGKTTQITQYLAEAGYTTRGKIGCTQPRRVAAMSVAKRVSEEYGCCLGQEVGYTIRFEDCTSPETVIKYMTDGMLLRECLIDPDLGQYAIIMLDEAHERTIHTDVLFGLLKKTVQKRTDMKLIVTSATLDAVKFSQYFYEAPIFTIPGRTYPVEVLYTKEPETDYLDASLITVMQIHLTEPPGDILVFLTGQEEIDTACEILYERMKSLGPDVPELIILPVYSALPSEMQTRIFDPAPPGSRKVVIATNIAETSLTIDGIYYVVDPGFVKQKVYNSKTGIDQLVVTPISQ--AQAKQRAGRAGRTGPGKCYRLYTERAYRDEMLTTNVPEIQRTNLASTVLSLKAMGINDLLSFDFMDAPPMETLITAMEQLYTLGALDDEGLLTRLGRRMAEFPLEPMLCKMLIMSVHLGCSEEMLTIVSMLSVQNVFYRPKDKQALADQKKAKFHQPEGDHLTLLAVYNSWKNNKFSNPWCYENFIQARSLRRAQDIRKQMLGIMDRHKLDVVSCGKATVRVQKAICSGFFRNAAKKDPQEGYRTLIDQQVVYIHPSSALFNRQPEWVVYHELVLTTKEYMREVTTIDPRWLVEFAPAFFKVSDPTRLSKQKKQQRLEPLYNRYE-EPNAWRISRAFRRR--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z9L3-1", "uniprot_id": "DHX8_DROME", "id": "A1Z9L3-1", "name": "ATP-dependent RNA helicase DHX8", "aln": "------------------MDELQKLEYLSLVSKICTELDNHLGINDKDLAEFIIDLENKNRTYDTFRKALLDNGAEFPDSLVQNLQRIINLMRPSRPGGASQEKTVGDKKEDKKSQLLKMFPGLALPNDTYSKKEESDDDEKVKAKPEKHSETHKKTDMSDVDAAMMELEALAPGEGATL---VRPHKEVSSRDRHKRRSRDRDTKR-RSRSRED---------------RHSDRRRSRSRDKERRRRSRSRDNRRRSRSREDRDRDRDRRHKSSSSRDHHERRRRSRSRSTERRDRRDRSRDCSEKMPPPSAAMTDDPEAGKIYSGKIANIVPFGCFVQLFGLRKR-WEGLVHISQLRAEGRVTDVTEVVTRNQTVKVKVMSITG-QKVSLSMKEVDQDSGKDLNP---LSHAPEDDESLRDRNPDGPFSSSTSMLNLQGNGMEGDEHESRKRVTRISSPERWEIKQMISSGVLDRSEMPDFDEETGL-------------------------LPKDEDDE-ADIEIEIVEEE-PPFLSG-HGRALHDLSPVRIVKNPDGSLAQAAMMQSALSKERREQKMLQREQEIEAMPTSLNKNWIDPLPEDESRSLAANMRGMAAAPPEVPEWKKHVIGGKKSSFGKKTDLTLVEQRQSLPIYKLRDDLIKAVTDNQILIVIGETGSGKTTQITQYLGECGFTARGKIGCTQPRRVAAMSVAKRVAEEYGCRLGQEVGYTIRFEDCTSPETIIKYMTDGMLLRECLMEAELKSYSVIMLDEAHERTIHTDVLFGLLKTAVQKRPELKLIVTSATLDAVKFSQYFFKAPIFTIPGRTFPVEVLYTKEPETDYLDASLITVMQIHLREPPGDILLFLTGQEEIDTACEILYERMKSLGPDVPELIILPVYSALPSEMQTRIFDPAPAGSRKVVIATNIAETSLTIDGIFYVVDPGFVKQKVYNSKTGMDSLVVTPISQ--AAAKQRAGRAGRTGPGKTYRLYTERAYRDEMLPTPVPEIQRTNLATTVLQLKTMGINDLLHFDFMDAPPVESLVMALEQLHSLSALDDEGLLTRLGRRMAEFPLEPNLSKMLIMSVALQCSDEILTIVSMLSVQNVFYRPKDKQALADQKKAKFNQAEGDHLTLLAVYNSWKNNKFSNAWCYENFVQIRTLKRSQDVRKQLLGIMDRHKLDVVSAGKNSVRIQKAICSGFFRNAAKKDPQEGYRTLVDSQVVYIHPSSALFNRQPEWVIYHELVQTTKEYMREVTTIDPKWLVEFAPSFFRFSDPTKLSKFKKNQRLEPLYNKYE-EPNAWRISRVRRRRN-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P24384-1", "uniprot_id": "PRP22_YEAST", "id": "P24384-1", "name": "Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP22", "aln": "------------------------------MSDISKLIGAIVGSDDPVIIEFVLNIINKSGNLQEFIRNIQKLDAGIS---YEDSIKMYNAFLG--------------KQEEEKVRNKVKSSPLSQKINQVLKDDVNLDDP-----------------------VVTEFVLSILNK-------SKSITEFQEQLNLMQSG--------------------------------------LDNETIFKIYQIAS---PPVMKEEVSVLPSTKIPAKIEAKIEEEVQK--------------------IESLDP------SPVLHKVYEGKVRNITTFGCFVQIFGTRMKNCDGLVHISEMS-DQRTLDPHDVVRQGQHIFVEVIKIQNNGKISLSMKNIDQHSG---------EIRKRNTESVEDRGRSND-------------AHTSRNMKNKIKRRALTSPERWEIRQLIASGAASIDDYPELKDEIPINTSYLTAKRDDGSIVNGNTEKVDSKLEEQQRDETDEIDVELNTDDGPKFLKDQQVKGAKKYEMPKITKVPRGFMNRSAINGSNAIRDHREEKLRKKREIEQQIRK--QQSFDDPTKNKKDSRNEIQMLKNQLI---VTEWEKNRMN-ESISYGKRTSLPISAQRQTLPVYAMRSELIQAVRDNQFLVIVGETGSGKTTQITQYLDEEGFSNYGMIGCTQPRRVAAVSVAKRVAEEVGCKVGHDVGYTIRFEDVTGPDTRIKYMTDGMLQREALLDPEMSKYSVIMLDEAHERTVATDVLFALLKKAAIKRPELKVIVTSATLNSAKFSEYFLNCPIINIPGKTFPVEVLYSQTPQMDYIEAALDCVIDIHINEGPGDILVFLTGQEEIDSCCEILYDRVKTLGDSIGELLILPVYSALPSEIQSKIFEPTPKGSRKVVFATNIAETSITIDGIYYVVDPGFAKINIYNARAGIEQLIVSPISQ--AQANQRKGRAGRTGPGKCYRLYTESAFYNEMLENTVPEIQRQNLSHTILMLKAMGINDLLKFDFMDPPPKNLMLNALTELYHLQSLDDEGKLTNLGKEMSLFPMDPTLSRSLLSSVDNQCSDEIVTIISMLSVQNVFYRPKDRQLEADSKKAKFHHPYGDHLTLLNVYTRWQQANYSEQYCKTNFLHFRHLKRARDVKSQISMIFKKIGLKLISCHSDPDLIRKTFVSGFFMNAAKRDSQVGYKTINGGTEVGIHPSSSLYGKEYEYVMYHSIVLTSREYMSQVTSIEPQWLLEVAPHFYKAGDAESQS--RKKAKIIPLHNKFAKDQNSWRLSSIRQSRERALGIKR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*.:.. :. :* :* : **::.: :*. : * : . .* :. : :: : : * : :* : . *. : : . :* .: *: . : * . . : . ..: : : ..* : :: : . * .* .:*.**: .* ******: * * : :******:: : *. : :** :.* : *:*:.: . * *****::**.:* . . *. *. . : .: : ::.**:***:*:*::.. . .: *::.:* : * : : :* ::::*: :: * ** . : : . . :*.* * * : ::*: * :::** * ::. : : :: : ** : .. :* :.**:*: :. :. *:**:*.:.: **::**:* ::.:*::** ***:*:::*************** * *:: * ***********:******:** ** :*::********* *.*:* ********* **.*::.:: .*::**********: *****.***.:. ** ::*:*******::.***:** :.**:.***:*:***:**:: *: **::*:* *::**: * *****:*********:.*****:*:*:** .: **:***********:*::**:*:* ******:********:*****:*******.* ::**:::*::.*:*:**** * *:** ********** ****** *: :*** . ****** **: *:* **:******* *****.** : :: *: :*: * :***** **.**:.*: **::* *.: *: ** **:*::**:**************:* **.*****::. ******* **. *:: ::*: :* **:: * *:*::*::.*: *:.: *.::*. . . ::*:: **** ****:*.* **:*: . * *****:*:.:: *:*:**.:* *::*** :**:*:*:**:*.** *:: .*. * :*: :: **:*:: : *:**:* : * ", "identical_positions": 463, "similar_positions": 347, "identity": "35.02%" }, { "cls_id": "homologset.agr.MGI:1306824", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AIH6-1", "uniprot_id": "A0A8I6AIH6_RAT", "id": "A0A8I6AIH6-1", "name": "Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial", "aln": "MASAVAIAAQAGKLLRERSLRPRLLAVRSQAGHLTPRRWLNLQEYQSKKLMSEHGVRVQRFFVASTAKEAQEAAKRLNAKEIVLKAQILAGGRGKGVFDSGLKGGVHLTKDPKVVGQLAQQMIGYNLATKQTPKEGVKVNKVMVAEALDISRETYLAILMDRSHNGPVLVGSPQGGVDIEEVAASSPELIFKEQIDIFEGIKDSQAQRMAENLGFLGSLKNQAADQIKKLYHLFLKIDATQVEVNPFGETPEGQVVCFDAKINFDDNAEFRQKDIFAMDDKSE-NEPIENEAARYDLKYIGLDGNIACFVNGAGLAMATCDIIFLNGGKPANFLDLGGGVKESQVYQAFKLLTSDPKVEAILVNIFGGIVNCAIIANGITKACQELELKVPLVVRLEVVLGAQAASLKTQTLMESHCLCPEVQVRTQGKPKATTHHRVP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z2I8-1", "uniprot_id": "SUCB2_MOUSE", "id": "Q9Z2I8-1", "name": "Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial", "aln": "MASPVAIAAQAGKLLRERALRP-LLAVRSQAGHLTPRRWLNLQEYQSKKLMSEHGVRVQRFFVANTAKEALEAAKRLNAKEIVLKAQILAGGRGKGVFNSGLKGGVHLTKDPKVVGELAQQMIGYNLATKQTPKEGVKVNKVMVAEALDISRETYLAILMDRSHNGPVIVGSPQGGVDIEEVAASSPELIFKEQIDIFEGIKDSQAQRMAENLGFLGSLKNQAADQITKLYHLFLKIDATQVEVNPFGETPEGQVVCFDAKINFDDNAEFRQKDIFAMDDKSE-NEPIENEAARYDLKYIGLDGNIACFVNGAGLAMATCDIIFLNGGKPANFLDLGGGVKEAQVYEAFKLLTSDPKVEAILVNIFGGIVNCAIIANGITKACRELELKVPLVVRLEGTNVQEAQNILKSSGLP---ITSAVDLEDAAKKAVASVAKK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96I99-1", "uniprot_id": "SUCB2_HUMAN", "id": "Q96I99-1", "name": "Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial", "aln": "MAS--PVAAQAGKLLRALALRPRFLAAGSQAVQLTSRRWLNLQEYQSKKLMSDNGVRVQRFFVADTANEALEAAKRLNAKEIVLKAQILAGGRGKGVFNSGLKGGVHLTKDPNVVGQLAKQMIGYNLATKQTPKEGVKVNKVMVAEALDISRETYLAILMDRSCNGPVLVGSPQGGVDIEEVAASNPELIFKEQIDIFEGIKDSQAQRMAENLGFVGPLKSQAADQITKLYNLFLKIDATQVEVNPFGETPEGQVVCFDAKINFDDNAEFRQKDIFAMDDKSE-NEPIENEAAKYDLKYIGLDGNIACFVNGAGLAMATCDIIFLNGGKPANFLDLGGGVKEAQVYQAFKLLTADPKVEAILVNIFGGIVNCAIIANGITKACRELELKVPLVVRLEGTNVQEAQKILNNSGLP---ITSAIDLEDAAKKAVASVAKK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1R7X5-1", "uniprot_id": "F1R7X5_DANRE", "id": "F1R7X5-1", "name": "Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial", "aln": "MAASVACQAAARGLRS--ASTKQLLVCRNQLTRVSPRRWLNLQEYQSKKLMQDSGVAVQRFFVADTASEALEAAKRLKAKEIVLKAQILAGGRGKGVFNSGLKGGVHLTKDPAVVGELASKMLGYNLTTKQTPKEGVEVKTVMVAEALDISRETYFAILMDRSCNGPVMVGSPQGGMDIEEVAAATPELIFKEVIDIFEGVRDDQALRMAANLGFKGPLERQAADQIKRLYDLFLKVDATQVEVNPLGETPEGQVVCFDAKINFDDNAEFRQKAVFSMDDTAE-SDPIETEAAKYDLKYIGMDGNIACFVNGAGLAMATCDIIDLHGGKPANFLDLGGGVKENQVYAAFKLLTADPKVEAILVNIFGGIVNCAIIANGITKACRELELKVPLVVRLEGTNVHEAKRILSESGLP---ITSATDLDDAARKAVAAIAKK-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V470-1", "uniprot_id": "Q9V470_DROME", "id": "Q9V470-1", "name": "Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial", "aln": "-----------------MSFLLKAVTTARHIVHKVPVRNLNLLEFQSKDLLQKYGVAIQQFKVLNNSKADAEVVKTFECPEYVVKAQILAGGRGKGTFDNGFKGGVHITTNKSEVLSLTQQMIGNRLITKQTPKSGILVNKVMVARSINITRETYLCILLDREHNGPVLIASPAGGMDIEAVAEETPEKIKTVPLDIGKPIPESTLLEVAKFLEFKGDSVKRCAEEIQKLYTLFKAVDAVQIEINPLAETDKGEVISVDAKLNFDDNAQFRQKDIFSMDVTEEESDPREVEAAKYNLNYVAMDGNIGCLVNGAGLAMATMDIIKLNGGEPANFLDVGGGVREDQVAKAFEILTADPKVKGILVNVFGGIVNCATIANGIVAASKKLQLNVPLVVRLEGTNVNQAREILKNSGLP---IQTASDLDDAAHKAVAALN---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :. : : . * *** *:***.*:.. ** :*:* * ..:. *..* ::. * *:************.*:.*:*****:*.: * .*:.:*:* .* ******.*: *:.****.:::*:****:.**:**. ****::.** **:*** ** .** * . :** : : :. .:* * * * :.*::* :** ** :**.*:*:**:.** :*:*:..***:******:**** :*:** . * .:* * ***:*:*:*:.:****.*:********** *** *:**:******:****:* ** **::**:****:.****:******** *****. *.::*:*:******** . :* : ..: : : . :: .: .:: ", "identical_positions": 198, "similar_positions": 125, "identity": "45.1%" }, { "cls_id": "homologset.agr.MGI:1306825", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZU18-1", "uniprot_id": "A0A8I5ZU18_RAT", "id": "A0A8I5ZU18-1", "name": "Putative GTP-binding protein 6", "aln": "MRRAVLPVCHCFTHPGARARAMLFPRVAALPGIWLLRVRRVQHALSLAGTLPRPVRAVSAG-SRALG---SVWASDGPVRGGG--------PEDPREDEEEEE--LLRVPPLLPFDAQRVCVLHPDVKRPAGKTPR---STAEWQVAEAAALVRALPGWSVARTLVVSSAAPGSRQVFGKG---NFRDLTEKIRGCQDITSVFLNVERMTPQTQKELETAWGLRVFDRFTLVLHIFRCNARTREARMQLALAEIPLLRSSVSGDSEQQDQQGWGSRYIMGSGESFSELRARALRDRELRLRRVLERLRDKRRLMRKERVRREFPVVSVVGYTNCGKTTLIRALTGEATLQPRDQPFATLDVTVHEGRLPSRLRVLYVDTIGFLSQLPHSLIHAFSATLEDVAYSDVLVHVTDVSHPDAELQKATVLSTLRGLGLRPA-------LLESAVEVHSKVDLVPGHTTPCSG-ALAVSAVSGRGLDELKAALEASVLRATGRQLLTIRVRLGGPQLGWLYNEAVVQQVQELPEG-GAAHVTVVITQAAYGRFQKLFPTDITSDPHTD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3U6U5-1", "uniprot_id": "GTPB6_MOUSE", "id": "Q3U6U5-1", "name": "Putative GTP-binding protein 6", "aln": "---------------------MLFLRAAVLPGFWLPRVRRVQLVRSPAVTLPSPVRTVHAG-SRVWG---SAWAGGGPVRGGG--------EEDPREDEEEEEDELLRAPPLLPLDTQRVCVLHPDVKRPAGKKPR---STAEWQVAEAAALVRALPGWSVASTLVVPSAAPGSRLVFGKG---NFQDVTEKIKGCQDITSVFLNVERMAPPTKKELESAWGLRVFDRFTLVLHIFRCNARTREARMQLALAEIPLLRSSVNTDSGQQDQQGWGSRYIMGSGESPTELRARALRDRELRLRRVLERLRDKRRLMRKERVRREFPVVSVVGYTNCGKTTLIQALTGEAALQPRDQPFATLDVTVHAGLLPSRLRILYVDTIGFLSQLPHNLIHAFSATLEDVAYSDVLVHVTDVSHPDAELQKATVLSTLRGLHLPPA-------LLESALEVHSKVDLVPGYTPPCSG-ALAVSAISGRGLDELKAALEASVLRATGRQVLTLCVRLGGPQLGWLYKEAVVQQVQELPEG-DAAHVTVVITQAAYGRFRKLFPIDAPSALPH-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43824-1", "uniprot_id": "GTPB6_HUMAN", "id": "O43824-1", "name": "Putative GTP-binding protein 6", "aln": "---------------------MWALRAAVRPGLRLSRVGRGRSAPRAAAPSCPARALAAVG-RRSPGNLEGPWGGGRGLRADGGRSRTGDDEEEPEDADENAEEELLRGEPLLPAGTQRVCLVHPDVKWGPGKSQM---TRAEWQVAEATALVHTLDGWSVVQTMVVSTKTPDRKLIFGKG---NFEHLTEKIRGSPDITCVFLNVERMAAPTKKELEAAWGVEVFDRFTVVLHIFRCNARTKEARLQVALAEMPLHRSNLKRDVAHLYR-GVGSRYIMGSGESFMQLQQRLLREKEAKIRKALDRLRKKRHLLRRQRTRREFPVISVVGYTNCGKTTLIKALTGDAAIQPRDQLFATLDVTAHAGTLPSRMTVLYVDTIGFLSQLPHGLIESFSATLEDVAHSDLILHVRDVSHPEAELQKCSVLSTLRGLQLPAP-------LLDSMVEVHNKVDLVPGYSPTEPN-VVPVSALRGHGLQELKAELDAAVLKATGRQILTLRVRLAGAQLSWLYKEATVQEVDVIPED-GAADVRVIISNSAYGKFRKLFPG---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B3J4-1", "uniprot_id": "A0A8M3B3J4_DANRE", "id": "A0A8M3B3J4-1", "name": "Putative GTP-binding protein 6", "aln": "MNLNKISVLTRHVFLCKHVLSRSYVRFAKCEVVRFPQCASKLIVNTLPSQSLKPGLVVPVLPARTLSLTARMFKYDNTDDNNV--------EEDEIDDAEIEKLFQEQIPSGIGKEDHRVFIVHPDVKWGSRKQYL---TTAALQMEEAVGLVKTLHKWSVVDKLILSTKTPEKKRIFGKG---NFQMLTEKIRATPGVTAVFVNVERLSPSSEKDLEEAWGVKVLDRYSLVLHIFRCNAKTKEAKLQISLAEIPLFRSRLRNEVANLDQQGGGPRYIMGSGETLYEMQQRLLKERELKIRSALERLRRKRNLLRSQRKHKDFPIISVMGYTNCGKTTLIKALTGDDGLQPKDQLFATLDVTVHAGQLPCHMTVLYVDTIGFLSQLPHQLIDSFSATLEDVIHSDLIIHVRDISHPETVSQKVNVLNVLNNLQIPER-------LLTSIIEVHNKIDLIEGYESSDPE-VIPISALKQCGLEALKEKIEEAVLKCTGKQMMTLKVQLNTSQLSWLYKEATVQAVDNVGDD-CTANVKVIISQAAYGRYRKLFQVTS-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VBQ7-1", "uniprot_id": "Q9VBQ7_DROME", "id": "Q9VBQ7-1", "name": "Hflx-type G domain-containing protein", "aln": "-----------MSALRILARFVSTRTLRIRPILEIPARCKYTQHQGVKGIRNRKSFFEAQIQAGQQGEEDADLERTANSDLADMR------FLDDRAYDEVAGGAMRITRDIAS--SQQVLILQPYVKWAAKRQNAPVDVRPEDQLAEATALIHSLPNWQVARALKVPLESLEKKTLFGSGKLVELKELVAELRQERHLTCLFVSKGTLSFAQKRFLEAEFRLPVMDRYSVVIQILRLHATSAEAKLQVAMAELPYIWAQAKDASVTQTR---------RQGYALTDLQKEILRTRERKLRAELDRVRRQRQLLRQKRKQQNYPIVAVVGYTNAGKTSLIKALTVEDALQPRNQLFATLDVTAHAGCLPCNLEVIYMDTVGFMSDLPTGLFECFVATLEDAMLADVIVHVQDLSHPCHAAQRSHVEATLRSLAFNVAGGDSTASQLPPIINVYNKCDLVSQEAQSSADPVHHISARAQTGLEPLLDDIEQQILTATGRRKLQMRVPSGGPEMAWLYKNAAVVETTADAENPERLMMHVVISQRTLDQFKRQFCR---------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . : * ::* :::* ** . : . *: **..*:::* *.*. : :. : : :**.* ::. :. ::: :*.:*:. :: :: ** : : *:**:::*::*:* :* : **::*:::**:* : : .* : ::: . *: :* ::* *:*:* :*.*:* :* ::::*:::*:****.***:**:*** : :**::* *******.* * **..: ::*:**:**:*:** *:..* *****. :*:::** *:*** *: * .*..* : * . ::*:.* **: . . . :** **: * :: :* .**:: : : * .::.***::*.* . :. : *:*:: : .:::: * ", "identical_positions": 119, "similar_positions": 157, "identity": "21.14%" }, { "cls_id": "homologset.agr.MGI:1306826", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZQP6-1", "uniprot_id": "D3ZQP6_RAT", "id": "D3ZQP6-1", "name": "Semaphorin-7A", "aln": "MTPPPPGRAAPSAPRARVLSLPARFGLPLRLRLLLVFWVTAASAQGHSRSGPRISAVWK---GQDHVDFGQPEPHNVLFHEPGSFSVWVGGRGKVYLFNFPEGKNASVRTVNIGSTKGSCQDKQDCENYITLLERRGNGLLVCGTNARKPSCWNLVN---DSVVMSLGEMKGYAPFSPDENSLVLFEGDEVYSTIRKQEYNGKIPRFRRIRGE-SELYTSDTVMQNPQFIKATIVH-QDQAYDDKIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSKWNTFLKAMLVCSDAATNRNFNRLQDVFLLPDPSGQWRDTRVYGVFSNPWNYSAVCVYSLGDIDRVFRTSSLKGYHMGLPNPRPGMCLPKKQPIPTETFQVADSHPEVAQRVEPMGPLKTPLFHSKYHYQKVVVHRMQASNGETFHVLYLTTDRGTIHKVVESGDQEHSFVFNIMEIQPFHRAAAIQAISLDADRRKLYVTSPWEVSQVPLDMCGVYSGGCHGCLMSRDPYCGWDQDQDRCVSIYSSQRSVLQSINPAEPHRECPNPNPDE------APLQKVSLARNSRYYLTCPMESRHATYLWRHEENVEQSCEPGHQSPSCILFIENLTARQYGHYRCEAQEGSYLHEAQHWELLPE-DRALAEQLLGHARALAASFWLGVLPTLVLGLLVH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QUR8-1", "uniprot_id": "SEM7A_MOUSE", "id": "Q9QUR8-1", "name": "Semaphorin-7A", "aln": "MTPPPPGRAAPSAPRARVLSLPARFGLPLRLRLLLVFWVAAASAQGHSRSGPRISAVWK---GQDHVDFSQPEPHTVLFHEPGSFSVWVGGRGKVYHFNFPEGKNASVRTVNIGSTKGSCQDKQDCGNYITLLERRGNGLLVCGTNARKPSCWNLVN---DSVVMSLGEMKGYAPFSPDENSLVLFEGDEVYSTIRKQEYNGKIPRFRRIRGE-SELYTSDTVMQNPQFIKATIVH-QDQAYDDKIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSKWNTFLKAMLVCSDAATNRNFNRLQDVFLLPDPSGQWRDTRVYGVFSNPWNYSAVCVYSLGDIDRVFRTSSLKGYHMGLPNPRPGMCLPKKQPIPTETFQVADSHPEVAQRVEPMGPLKTPLFHSKYHYQKVVVHRMQASNGETFHVLYLTTDRGTIHKVVESGDQDHSFVFNIMEIQPFHRAAAIQAISLDADRRKLYVTSQWEVSQVPLDMCEVYSGGCHGCLMSRDPYCGWDQD--RCVSIYSSQRSVLQSINPAEPHRECPNPKPDE------APLQKVSLARNSRYYLTCPMESRHATYLWRHEENVEQSCEPGHQSPSCILFIENLTARQYGHYRCEAQEGSYLREAQHWELLPE-DRALAEQLMGHARALAASFWLGVLPTLILGLLVH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75326-1", "uniprot_id": "SEM7A_HUMAN", "id": "O75326-1", "name": "Semaphorin-7A", "aln": "MTPPPPGRAAPSAPRARVPGPPARLGLPLRLRLLLLLWAAAASAQGHLRSGPRIFAVWKGHVGQDRVDFGQTEPHTVLFHEPGSSSVWVGGRGKVYLFDFPEGKNASVRTVNIGSTKGSCLDKRDCENYITLLERRSEGLLACGTNARHPSCWNLVN---GTVVP-LGEMRGYAPFSPDENSLVLFEGDEVYSTIRKQEYNGKIPRFRRIRGE-SELYTSDTVMQNPQFIKATIVH-QDQAYDDKIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSKWNTFLKAMLVCSDAATNKNFNRLQDVFLLPDPSGQWRDTRVYGVFSNPWNYSAVCVYSLGDIDKVFRTSSLKGYHSSLPNPRPGKCLPDQQPIPTETFQVADRHPEVAQRVEPMGPLKTPLFHSKYHYQKVAVHRMQASHGETFHVLYLTTDRGTIHKVVEPGEQEHSFAFNIMEIQPFRRAAAIQTMSLDAERRKLYVSSQWEVSQVPLDLCEVYGGGCHGCLMSRDPYCGWDQG--RCISIYSSERSVLQSINPAEPHKECPNPKPDK------APLQKVSLAPNSRYYLSCPMESRHATYSWRHKENVEQSCEPGHQSPNCILFIENLTAQQYGHYFCEAQEGSYFREAQHWQLLPE-DGIMAEHLLGHACALAASLWLGVLPTLTLGLLVH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FBE1-1", "uniprot_id": "E7FBE1_DANRE", "id": "E7FBE1-1", "name": "", "aln": "-------------------MIRHYSSLKFKGNLAYPWLIYGACFQCVFCSCNPRLTLKQ---DNAPLNYNTNYSHTVLFHEEGSKSLFVGGSNIVLHFDVDSYEILENFTLNANLPR---CGESSCENVVTVIETFQNCKFVCGTNGEEPQCWELYPRESNHSVVKSVEGTGISPHSSEQNSLSLVADGDLYAAAP-LYSDGTLLQFRRKAGKRINVWMHDQWVSEPTFISSFLAKRKNDSLNEKIYVLFREKNSDTSPEADPWISRVARVCKIDEGGSKQFLQNIWTSFLKARLVCGIPKESLYFNRLQDVFVQH--AEDWRDSLVYALFSSSWNSTAVCIYSLADLDDIFEKSNYKGFSEAIPNPRPGKCVENSNSLPIPTLKIIKDYPEMKDWIHPIQ-KDTPFFTSSKNFTKIVVDQIRALDENVYNVLLLATDDGMIFKILQHGSK----PFIISETHLCNGCAPIQSMKLDSKKRKLFVGYPGQMSVLELQRCQDYGASCEECVLSRDPYCAWSEKGCTSQTRGGIQNISDGNVTKVCDHKSVGRVRRDAQQSSTAPSRIQHTVATDVPFYLSCPVDSHHASYRWEHGG---KSNPCQQTQSEYLLLIPAMTAENYGNYSCVSQERDYIKVVREYELLAKSVFNDAFKLKIQDRQLMVAFVTSAFYLCSL-----", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 192, "similar_positions": 236, "identity": "28.19%" }, { "cls_id": "homologset.agr.MGI:1309453", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XIW8-1", "uniprot_id": "SNUT1_RAT", "id": "Q5XIW8-1", "name": "U4/U6.U5 tri-snRNP-associated protein 1", "aln": "MGSSKKHRGEKEAAGTTAAAGTGGTTEQPPRHREHKKHKHRSSGGGSSGGERRKRSRERGAERGSGRRGAEAEARSGAHGRERSQAEPSERRVKREKRDEGYEAAASSKASSGDASSLSIEETNKLRAKLGLKPLEVNAVKKEAGTKEEPVAADVINPMALRQREELREKLAAAKEKRLLNQKLGKIKTLGEDDPWLDDTAAWIERSRQLQKEKDLAEKRAKLLEEMDQEFGVSTLVEEEFEQRRQDLYSARDLQGLTVEHAIDSFREGETVVLTLKDKGVLQEGE--DVLVNVNMVDKERADKNVELRKKKPDYLPYAEDESVDDLAQQKPRSILAKYDEELEGERPHSFRLEQGGMADGLRERELEEIRTKLRLQAQSLNTVGPRLASEYLSPEEMVTFKKTKRRVKKIRKKEKEVIMRADDLLPLGEDQTQDGDFGSRLRGRGRRRVPEVEEEALEDEEKDPVAQPPPSDDTRVENMDISDEEDGGALPSGPPE-LEEDEAELELQKQLEKGRRLRQLQQLQQLRDSGEKVLEIVKKLESRQRGWEEEEDPERKGTIVFNATSEFCRTLGEIPTYGLAGNREEQEELMDFERDEERSANGGSESDGEENIGWSTVNLDEEKQHQDFSASSTTILDEEPIVNRGLAAALLLCQNKGLLETTVQKVARVKAPNKSLPSAVYCIEDKMAIDDKYSRREEYRGFTQDFKEKDGYKPDVKIEYVDETGRKLTPKEAFRQLSHRFHGKGSGKMKTERRMKKLDEEALLKKMSSSDTPLGTVALLQEKQKAQKTPYIVLSGSGKSMNANTITK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z315-1", "uniprot_id": "SNUT1_MOUSE", "id": "Q9Z315-1", "name": "U4/U6.U5 tri-snRNP-associated protein 1", "aln": "MGSSKKHRGEKEAAGTTAAAGTGGTTEQPPRHREHKKHKHRSSGGGSSGGERRKRSRERGSERGSGRRGAEAEARSGAHGRERSQAEPSERRVKREKRDDGYEAAASSKASSGDASSLSIEETNKLRAKLGLKPLEVNAVKKEAGTKEEPVAADVINPMALRQREELREKLAAAKEKRLLNQKLGKIKTLGEDDPWLDDTAAWIERSRQLQKEKDLAEKRAKLLEEMDQEFGVSTLVEEEFEQRRQDLYSARDLQGLTVEHAIDSFREGETVVLTLKDKGVLQDGE--DVLVNVNMVDKERADKNVELRKKKPDYLPYAEDESVDDLAQQKPRSILAKYDEELEGERPHSFRLEQGGMADGLRERELEEIRTKLRLQAQSLSSVGPRLASEYLSPEEMVTFKKTKRRVKKIRKKEKEVIMRADDLLPLG-DQTQDGDFGSRLRGRGRRRVPEVEEEALEDEEKDPVAQPPPSDDTRVENMDISDEEDGGALPPGSPEGLEEDEAELELQKQLEKGRRLRQLQQLQQLRDSGEKVLEIVKKLESRQRGWEEEEDPERKGTIVFNATSEFCRTLGEIPTYGLAGNREEQEELMDFERDEERSANGGSESDGEENIGWSTVNLDEEKQHQDFSASSTTILDEEPIVNRGLAAALLLCQNKGLLETTVQKVARVKAPNKSLPSAVYCIEDKMAIDDKYSRREEYRGFTQDFKEKDGYKPDVKIEYVDETGRKLTPKEAFRQLSHRFHGKGSGKMKTERRMKKLDEEALLKKMSSSDTPLGTVALLQEKQKAQKTPYIVLSGSGKSMNANTITK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43290-1", "uniprot_id": "SNUT1_HUMAN", "id": "O43290-1", "name": "U4/U6.U5 tri-snRNP-associated protein 1", "aln": "MGSSKKHRGEKEAAGTTAAAGTGGATEQPPRHREHKKHKHRSGGSGGSGGERRKRSRERGGERGSGRRGAEAEARSSTHGRERSQAEPSERRVKREKRDDGYEAAASSKTSSGDASSLSIEETNKLRAKLGLKPLEVNAIKKEAGTKEEPVTADVINPMALRQREELREKLAAAKEKRLLNQKLGKIKTLGEDDPWLDDTAAWIERSRQLQKEKDLAEKRAKLLEEMDQEFGVSTLVEEEFGQRRQDLYSARDLQGLTVEHAIDSFREGETMILTLKDKGVLQEEE--DVLVNVNLVDKERAEKNVELRKKKPDYLPYAEDESVDDLAQQKPRSILSKYDEELEGERPHSFRLEQGGTADGLRERELEEIRAKLRLQAQSLSTVGPRLASEYLTPEEMVTFKKTKRRVKKIRKKEKEVVVRADDLLPLG-DQTQDGDFGSRLRGRGRRRVSEVEEE------KEPVPQPLPSDDTRVENMDISDEEEGGAPPPGSPQVLEEDEAELELQKQLEKGRRLRQLQQLQQLRDSGEKVVEIVKKLESRQRGWEEDEDPERKGAIVFNATSEFCRTLGEIPTYGLAGNREEQEELMDFERDEERSANGGSESDGEENIGWSTVNLDEEKQQQDFSASSTTILDEEPIVNRGLAAALLLCQNKGLLETTVQKVARVKAPNKSLPSAVYCIEDKMAIDDKYSRREEYRGFTQDFKEKDGYKPDVKIEYVDETGRKLTPKEAFRQLSHRFHGKGSGKMKTERRMKKLDEEALLKKMSSSDTPLGTVALLQEKQKAQKTPYIVLSGSGKSMNANTITK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q12420-1", "uniprot_id": "SNU66_YEAST", "id": "Q12420-1", "name": "66 kDa U4/U6.U5 small nuclear ribonucleoprotein component", "aln": "----------------------------------------------------------------------------MNKTENLSIEETNEIREKLGMKP----IPVFQEKNTDHKESLSIEETNELRASLGLKLIPP----------QQNFNSSPPNVHNTSKIDELREKITKFQKK--ANAPLRMAHLLEETN--VNDDSSWLENMDAIPSSHESKRS--------------STLPRKGATKEDE----NIDLHNVQVSYNIEALSPKKDTILTLKESSIFDDTDSTEVLENVKAAEENADREKLRLRQMNKDRRQKKKILNVSSLDIEE-----EEEGEKHSITTTHLIIGAEQGVMKAPNTISAKPPTGKVKVNFDSANNMSDEDGGDFKP----LKIKKRKIKDPRSTKARKSKITDKMEIVKLVDEDES---------------LSWMEEE-------QPVTIINPRTSSNNE-----------------LKGPEDLAREIEKARDEEK-RRTESILKMREISNS-IVVDEKVTFLNTLDTSLSERSATENK----VKVHGEGEKNIGDVTN-GHTKEGSGNNTLTEAVNNE--PNYEGDAENAPNFFSGLASTLGYLRKKSVFTTGDVDLKPGKDVNNS--------------------ESLRRDVRNKEHTGTGTYTKDKLHGLEQFTSSDSSNANTHSKRQ-DHYDPDIKLVYRDEKGNRLTTKEAYKKLSQKFHGTKSNKKKRAKMKSRIEARKNTPEN-------GSLFEFDDN-------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .: * *..* * * : .. .: .:.. .********:***.**** : :: . :. * : :*****:: ::* * * : * * : ::* ::*:*. : ..:: .. *** .: :. : **:.: *.: *::: : :****:..:::: : :** **: .::: :::.**: : * : .*..* :: : .*: . .* : : * .. . . : *:::: :* ..:. . ..:: . :.:** * : : * .*. : ::: * :: . :. :*** :**. * .:. * : *: *:* :: ** ** ..: ::::: :* * * *. *:: : . .* . .*.* .:. .* :.:*::.. * : : . :: * : .:* . *. .:. : :. : .*. :::. *::... : : : * : * .. **. ..: :**: :::: :. .. *:. :: * *.**:*: * **.*.:**.***:::**::***. *.* * : .::: . : *:: :::: ", "identical_positions": 125, "similar_positions": 247, "identity": "15.45%" }, { "cls_id": "homologset.agr.MGI:1309463", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BM72-1", "uniprot_id": "HSP13_MOUSE", "id": "Q8BM72-1", "name": "Heat shock 70 kDa protein 13", "aln": "MAGEMTILGSAVLTLLLAGYLAQQYLPLPTPKVIGIDLGTTYCSVGVFFPGTGKVKVIPDENGHISIPSMVSFTDGDVYVGYESLELADSNPQNTIYDAKRFIGKIFTPEELEAEVGRYPFKVLHRNGMAEFSVTSNETIIVSPEFVGSRLLLKLKEMAEEYLGMPVANAVISVPAEFDLQQRNSTIQAANLAGLKILRVINEPTAAAMAYGLHKVDVFYVLVIDLGGGTLDVSLLNKQGGMFLTRAMSGNNKLGGQDFNQRLLQHLYKEIYQTYGFLPSRKEEIHRLRQAVEMVKLNLTIHQSAQVSVLLTVEGKDSKEPQNGDSELPKDQLTPGDGHHVNRVFRPGLSESKSGKSQVLFETEVSRKLFDALNEDLFQKILVPIQQVLKEGLLDKTEIDEVVLVGGSTRIPRIRQVIQEFFGKDPNTSVDPDLAVVTGVAIQAGIDGGSWPLQVSALEIPNKHLQKTNFN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O35162-1", "uniprot_id": "HSP13_RAT", "id": "O35162-1", "name": "Heat shock 70 kDa protein 13", "aln": "MAGEMTILGSAVLTLLLAGYLAQQYLPLPTPKVIGIDLGTTYCSVGVFFPGTGKVKVIPDENGHISIPSMVSFTDGDVYVGYESLELADSNPQNTIYDAKRFIGKIFTPEELEAEIGRYPFKVLHKNGMAEFSVTSNETIIVSPEYVGSRLLLKLKEMAEKYLGMPVANAVISVPAEFDLQQRNSTIQAANLAGLKILRVINEPTAAAMAYGLHKVDVFYVLVIDLGGGTLDVSLLNKQGGMFLTRAMSGNNKLGGQDFNQRLLQYLYKEIYQTYGFLPSRKEEIHRLRQAVEMVKLNLTLHQSAQVSVLLTVEENDSQKPQNADSKLPEDQLTPGDGHHVNRVFRPGLSDSTSGKSQVLFETEVSRKLFNTLNEDLFQKILVPIQQVLKEGLLDKTEIDEVVLVGGSTRIPRIRQVIQEFFGKDPNTSVDPDLAVVTGVAIQAGIDGGSWPLQVSALEIPNKHLQKTNFN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P48723-1", "uniprot_id": "HSP13_HUMAN", "id": "P48723-1", "name": "Heat shock 70 kDa protein 13", "aln": "MAREMTILGSAVLTLLLAGYLAQQYLPLPTPKVIGIDLGTTYCSVGVFFPGTGKVKVIPDENGHISIPSMVSFTDNDVYVGYESVELADSNPQNTIYDAKRFIGKIFTAEELEAEIGRYPFKVLNKNGMVEFSVTSNETITVSPEYVGSRLLLKLKEMAEAYLGMPVANAVISVPAEFDLKQRNSTIEAANLAGLKILRVINEPTAAAMAYGLHKADVFHVLVIDLGGGTLDVSLLNKQGGMFLTRAMSGNNKLGGQDFNQRLLQYLYKQIYQTYGFVPSRKEEIHRLRQAVEMVKLNLTLHQSAQLSVLLTVEEQDRKEPHSSDTELPKDKLSSADDHRVNSGFGRGLSDKKSGESQVLFETEISRKLFDTLNEDLFQKILVPIQQVLKEGHLEKTEIDEVVLVGGSTRIPRIRQVIQEFFGKDPNTSVDPDLAVVTGVAIQAGIDGGSWPLQVSALEIPNKHLQKTNFN", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** ************************************************************************.********:***********************.******:********::***.********** ****:************** *******************:******:***************************.***:*********************************************:***:*******:**********************:*****:******* :* ::*:..*::**:*:*:..*.*:** * ***:..**:********:*****::******************** *:****************************************************************************", "identical_positions": 421, "similar_positions": 40, "identity": "89.38%" }, { "cls_id": "homologset.agr.MGI:1309464", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9R237-1", "uniprot_id": "JIP1_RAT", "id": "Q9R237-1", "name": "C-Jun-amino-terminal kinase-interacting protein 1", "aln": "------MAERESG-LSGGAASPPAASPFLGLHIASPPNFRLTHDISLEEFEDEDLSEITDECGISLQCKDTLSLRPPRAGLLSAGSSGSAGSRLQAEMLQMDLIDAASDTPGAEDDEED-DDELAAQRPGVGPSKAESGQEPASRSQGQGQG--PGTGS-GDTYRPKRPTTLNLFPQVPRSQDTLNNNSLGKKHSWQDRVSRSSSPLKTGEQTPPHEHICLSDELPPQG-------SPVPTQDRGTSTDSPCRRTAATQMAPPSGPPATAPGGRG----------------------------HSHRDRIHYQADVR-----------------LEATEEIYLTPVQR---PPDPAEPTSTFLPPTESRMSVSSD--PDPAAYSVTAGRPHPSISEEDEGFDCLS---SPEQAEPPGGGWRGSLGEPPPPPR--------ASLS-SDTSALSYDSVKYTLVVDEHAQLELVSLRPCFGDYSDE-SDSATVYDNCASASSPYESAIGEEYEEAPQ--PRPPTCLS---EDSTPDEPDVHFSKKFLNVFMSGRSRSSSAESFGLFSCVINGEEHEQTHRAIFRFVPRHEDELELEVDDPLLVELQAEDYWYEAYNMRTGARGVFPAYYAIEVTKEPEHMAALAKNSDWIDQFRVKFLGSVQVPYHKGNDVLCAAMQKIATTRRLTVHFNPPSSCVLEISVRGVKIGVKAD--EAQEAKGNKCSHFFQLKNISFCGYHPKNNKYFGFITKHPADHRFACHVFVSEDSTKALAESVGRAFQQFYKQFVEYTCPTEDIYLE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WVI9-1", "uniprot_id": "JIP1_MOUSE", "id": "Q9WVI9-1", "name": "C-Jun-amino-terminal kinase-interacting protein 1", "aln": "------MAERESG-LGGGAASPPAASPFLGLHIASPPNFRLTHDISLEEFEDEDLSEITDECGISLQCKDTLSLRPPRAGLLSAGSSGSAGSRLQAEMLQMDLIDAAGDTPGAEDDEEEEDDELAAQRPGVGPPKAESNQDPAPRSQGQG----PGTGS-GDTYRPKRPTTLNLFPQVPRSQDTLNNNSLGKKHSWQDRVSRSSSPLKTGEQTPPHEHICLSDELPPQG-------SPVPTQDRGTSTDSPCRRSAATQMAPPSGPPATAPGGRG----------------------------HSHRDRIHYQADVR-----------------LEATEEIYLTPVQR---PPDPAEPTSTFMPPTESRMSVSSD--PDPAAYSVTAGRPHPSISEEDEGFDCLS---SPERAEPPGGGWRGSLGEPPPPPR--------ASLS-SDTSALSYDSVKYTLVVDEHAQLELVSLRPCFGDYSDE-SDSATVYDNCASASSPYESAIGEEYEEAPQ--PRPPTCLS---EDSTPDEPDVHFSKKFLNVFMSGRSRSSSAESFGLFSCVINGEEHEQTHRAIFRFVPRHEDELELEVDDPLLVELQAEDYWYEAYNMRTGARGVFPAYYAIEVTKEPEHMAALAKNSDWIDQFRVKFLGSVQVPYHKGNDVLCAAMQKIATTRRLTVHFNPPSSCVLEISVRGVKIGVKAD--DALEAKGNKCSHFFQLKNISFCGYHPKNNKYFGFITKHPADHRFACHVFVSEDSTKALAESVGRAFQQFYKQFVEYTCPTEDIYLE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UQF2-1", "uniprot_id": "JIP1_HUMAN", "id": "Q9UQF2-1", "name": "C-Jun-amino-terminal kinase-interacting protein 1", "aln": "------MAERESGGLGGGAASPPAASPFLGLHIASPPNFRLTHDISLEEFEDEDLSEITDECGISLQCKDTLSLRPPRAGLLSAGG-GGAGSRLQAEMLQMDLIDATGDTPGAEDDEEDDDEERAARRPGAGPPKAESGQEPASRGQGQSQGQSQGPGS-GDTYRPKRPTTLNLFPQVPRSQDTLNNNSLGKKHSWQDRVSRSSSPLKTGEQTPPHEHICLSDELPPQS-------GPAPTTDRGTSTDSPCRRSTATQMAPPGGPPAAPPGGRG----------------------------HSHRDRIHYQADVR-----------------LEATEEIYLTPVQR---PPDAAEPTSAFLPPTESRMSVSSD--PDPAAYPSTAGRPHPSISEEEEGFDCLS---SPERAEPPGGGWRGSLGEPPPPPR--------ASLS-SDTSALSYDSVKYTLVVDEHAQLELVSLRPCFGDYSDE-SDSATVYDNCASVSSPYESAIGEEYEEAPR--PQPPACLS---EDSTPDEPDVHFSKKFLNVFMSGRSRSSSAESFGLFSCIINGEEQEQTHRAIFRFVPRHEDELELEVDDPLLVELQAEDYWYEAYNMRTGARGVFPAYYAIEVTKEPEHMAALAKNSDWVDQFRVKFLGSVQVPYHKGNDVLCAAMQKIATTRRLTVHFNPPSSCVLEISVRGVKIGVKAD--DSQEAKGNKCSHFFQLKNISFCGYHPKNNKYFGFITKHPADHRFACHVFVSEDSTKALAESVGRAFQQFYKQFVEYTCPTEDIYLE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AUR2-1", "uniprot_id": "A0A8M3AUR2_DANRE", "id": "A0A8M3AUR2-1", "name": "", "aln": "------MDSNGDG---------------NDEWTEEQWEKWLTHDIGLDEFEDEDLSEITEIT-------DEYAFKARRN-----------DSDIKDHVRQAPSAALGRIEAGAEG------QIQPETQPLHLTDAADRSQTLACRHDSKASMDSAVPVS-MEAYRPKRPTTLNLFPQVPRTQDTLNNNSFSKKFSWQQKISQTLPPRKGADLTPPCEHTCLSDEEKHQP-------SRAQMKDCGTSTTD--KPNICPSKHTP-APAAAVYKPRE----------------------------AAHCERIRYHTDVR-----------------LEPTEEIYLTPIQRCTEPPETQKTKVMVSSDSEAPPPYSEQDLQPPSYFSCVEALAVDSSGDEEPTVDDLC---YRDCG---AGEAHAHHENLPKIIH--------TSMSNSDASGLSYDSVKYTLVVDEHDQLELVSLKECYRGYSDD-SESPTVYDNCVS--SPYESGLDKEYEEEND--GEKLSRIKASFEDSTP-EADIPFSRKFVNVFMNGCSRSSSTESFGLFSCLINGEEREQTHRAVYRFIPRHDDELELELNDPLLVELQDEDYWYEGYNMRTGARGIFPAYYATEVFREQELASDEVKSSEWVEKYTMKFLGSVQVMNHKGNDVLCAAMQKIAMNRRLTVHYNPPSSCILEITVKGLKLTVQDD--FDMSS---QYSHFFHLKNVSFCGYHPRNKKYFGFITKHPADERFACHVFVSENSTKPLAESVRKAFHLYYKEFVEVSCPTEDIYLE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0R4IB08-1", "uniprot_id": "A0A0R4IB08_DANRE", "id": "A0A0R4IB08-1", "name": "", "aln": "MVLSLAMDSREEW----------------DGWMEEQWEKWLTHDISLDEYEDDDLSEVTEITDENGITLVHLDLDTQDHMTRPTNGAARSGRRREAVELQAEMLHLDLIDAEGGIQE----EERDDRRPFDAIDDNHKEERGAGPPVILPQLKTLTPANDMDTYRPKRPTTLNLFPQVPRTQDTINNNSFGEKERRKEKKTHSSSPHIKGDSAAKPEQGSLTDGDKVQARADTKPRGPASTKNKASAFQNKQQDKLSESLNNPTVVAPLTQTAMRDKSTEVPLIEGVLDISTICKEKARYHTVNGYREQVQYPAENEGMCDQLVDRNKDYHISEGNATEEIHLTPVNG-----EQERPFLSQSSDS-NRMSISSDTELPPLHYYPSAGCPNPSISEEDEVYPPTPPCRTVSLSEQPGDSSQWAETRKPKMAKDETGNVKAVAVS-TDASGLTYDSVKYTLVVDEHAKLELVSIKDCYKGYESD-SDN-TVYESAIDEDDEDQEADEEDEESGARSMRRDTSCLS--ADSTTDTTSDVPRSRKFMNIFGNGRSRFSGAE-FGFFSCVINGEEREQSHRAVFRFVPRHDDELELEADDPLLVELQAEDLWCEAYNMRTGTRGIFPAFYAVKVAKD--ELVKEVKG-DWMDKFWVKFLGSVQVPYHKGNDVLCAAMHKIASNRRTTMQFSPPSPCIVEINTRGLKIVVQDD--CRTSGRGEKCFHFFQLKNISFCGCHPKNNKYFGLITKHPANQRFACHVFFSDDTTTKLAESVGKAFQQFYKEHMEYSCPTEDIFLE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W0K0-1", "uniprot_id": "JIP1_DROME", "id": "Q9W0K0-1", "name": "JNK-interacting protein 1", "aln": "-----------------------------------------MADSEFEEFHRP----------------------------------------------IFEPHTIAGFGSGAGS------KKNNPHAFYSLIPNDDLEDSHSSKS---------------DGDGSDQEDGIGLVDHEPKMR-QVEDDELGDG---LKVTLSSDGSLDTNDSFNSHRHHPLNHQDAIGG-----------FLGMDTSGLGGNSAPVTIGASTDLLAPNTAATRRR---------------------------------------------------------------RKLPEIPKNK------------------------------KSSILHLLGGSNFGSLADEFR---------------------NGGGGGIPPAVR--------------SGQQRSFLSLKCGYLMDEDSSPDSERMQSLGDVDSGHSTAHS----------------------------PNDFKSMS---PQITSPVSQSPFPPPFGGVPFG------------------QLEMLEATHRGLHKFVPRHHDEIELEIGDAIYVQKEAEDLWCEGVNLRTGRQGIFPSAYAVDLDYNEFDPTVQLVK---KERYLLGYLGSVETLAHKGTGVVCQAVRKIVGEYGNSPTG---QTCILEVSDQGLRMVDRSGPNQNKKDKKPCIDYFYSLKNVSFCAFHPRDHRFIGFITKHPTVQRFACHVFKGSESTRPVAEAVGRAFQRFYQKFIETAYPIEDIYIE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * ::*:. . . . . : : : ..: :.*. : *: : ::::.:.. . : . : .: *.. . :: . . .:: * : . . * .:* . * : . . :: *:* ::**. . : :: ... : . :. . * .: . * .: . : * * :**.:.:*:***.**:*** .*.: *: : ** * *. *:*** :*:**: ** .: : ::: : :****:. ***..*:* *::**. : ..*::*:. :*::: : . . :*: ***:***. **::::::*:*****: .******* ..::* :**:* :**: :*::.:* : * ***::*", "identical_positions": 93, "similar_positions": 155, "identity": "11.68%" }, { "cls_id": "homologset.agr.MGI:1309465", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63632-1", "uniprot_id": "S12A4_RAT", "id": "Q63632-1", "name": "Solute carrier family 12 member 4", "aln": "MPHFTVVPVDGPRRGDYDNLEGLSWVDYGERAERE--------DSDGQGNHRENSPFLSPLD-ASRGNDYYDRNLALFEEELDIRPKVSSLLGKLVSYTNLTQGAKEHEEAESGEGGRRRAAKAPSMGTLMGVYLPCLQNIFGVILFLRLTWMVGTAGVLQALLIVLICCCCTLLTAISMSAIATNGVVPAGGSYFMISRSLGPEFGGAVGLCFYLGTTFAAAMYILGAIEILLTYIAPPAAIFYPSGTHDMSSATLNNMRVYGTIFLTFMTLVVFVGVKYVNKFASLFLACVIISILSIYVGGIKSAFDPPVFPVCMLGNRTLSRDQFDICAKTVVVDNETVATRLWTFFCHSPNLTADSCDPYFLLNNVTEIPGIPGAAAGVLQENLWSAYLEKGEVVEKHGLPSTDTLGLKESLSLYVVADIATSFTVLVGIFFPSVTGIMAGSNRSGDLRDAQKSIPVGTILAIVTTSLVYFSSVILFGACIEGVVLRDKYGDGVSRNLVVGTLAWPSPWVIVVGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHGKANGEPTWALLLTALIAELGILIASLDMVAPILSMFFLMCYLFVNLACAVQTLLRTPNWRPRFKYYHWALSFLGMSLCLALMFVSSWYYALVAMVIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARYALLRLEEGPPHTKNWRPQLLVLLKLDEDLHVKYPRLLTFASQLKAGKGLTIVGSVIQGSFLESYGEAQAAEQTIKNMMEIEKVKGFCQVVVASKVREGLAHLIQSCGLGGMRHNSVVLGWPYGWRQSEDPRAWKTFIDTVRCTTAAHLALLVPKNIAFYP-SNHERYLEGHIDVWWIVHDGGMLMLLPFLLRQHKVWKKCRMRIFTVAQMDDNSIQMKKDLAIFLYHLRLEAEVEVVEMHNSDISAYTYERTLMMEQRSQMLRQMRLTKTERDREAQLVKDR-------------------------HSALRLESLYSDEEDESVTG-ADKIQMTWTRDKYMAEPWDPSHAPDNFRELVH------IKPDQSNVRRMHTAVKLNEVIVTRSHDARLVLLNMPGPPK--NSEGDENYMEFLEVLTEGLERVLLVRGGGREVITIYS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JIS8-1", "uniprot_id": "S12A4_MOUSE", "id": "Q9JIS8-1", "name": "Solute carrier family 12 member 4", "aln": "MPHFTVVPVDGPRRGDYDNLEGLSWVDYGERAERE--------DSDGQGNHRENSPFLCPLD-ASRGNDYYDRNLALFEEELDIRPKVSSLLGKLVSYTNLTQGAKEHEEAESGEGGRRRAAKAPSMGTLMGVYLPCLQNIFGVILFLRLTWMVGTAGVLQALLIVLICCCCTLLTAISMSAIATNGVVPAGGSYFMISRSLGPEFGGAVGLCFYLGTTFAAAMYILGAIEILLTYIAPPAAIFYPSGTHDMSSATLNNMRVYGTIFLTLMTLVVFVGVKYVNKFASLFLACVIISILSIYAGGIKSIFDPPVFPVCMLGNRTLSRDQFDICAKTVVVDNETVATRLWTFFCHSPNLTADSCDPYFLLNNVTEIPGIPGAAAGVLQENLWSAYLEKGEVVEKHGLPSTDTLGLKESLSLYVVADIATSFTVLVGIFFPSVTGIMAGSNRSGDLRDAQKSIPVGTILAIVTTSLVYFSSVILFGACIEGVVLRDKYGDGVSRNLVVGTLAWPSPWVIVVGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHGKANGEPTWALLLTALIAELGILIASLDMVAPILSMFFLMCYLFVNLACAVQTLLRTPNWRPRFKYYHWTLSFLGMSLCLALMFVSSWYYALVAMLIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARYALLRLEEGPPHTKNWRPQLLVLLKLDEDLHVKYPRLLTFASQLKAGKGLTIVGSVIQGSFLESYGEAQAAEQTIKNMMDIEKVKGFCQVVVASKVREGLAHLIQSCGLGGMRHNSVVLGWPYGWRQSEDPRAWKTFIDTVRCTTAAHLALLVPKNIAFYP-SNHERYLDGHIDVWWIVHDGGMLMLLPFLLRQHKVWKKCRMRIFTVAQMDDNSIQMKKDLAIFLYHLRLEAEVEVVEMHNSDISAYTYERTLMMEQRSQMLRQMRLTKTERDREAQLVKDR-------------------------HSALRLESLYSDEEEESVAG-ADKIQMTWTRDKYMAEPWDPSHAPDNFRELVH------IKPDQSNVRRMHTAVKLNEVIVTRSHDARLVLLNMPGPPK--NSEGDENYMEFLEVLTEGLERVLLVRGGGREVITIYS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UP95-1", "uniprot_id": "S12A4_HUMAN", "id": "Q9UP95-1", "name": "Solute carrier family 12 member 4", "aln": "MPHFTVVPVDGPRRGDYDNLEGLSWVDYGERAELD--------DSDGHGNHRESSPFLSPLE-ASRGIDYYDRNLALFEEELDIRPKVSSLLGKLVSYTNLTQGAKEHEEAESGEGTRRRAAEAPSMGTLMGVYLPCLQNIFGVILFLRLTWMVGTAGVLQALLIVLICCCCTLLTAISMSAIATNGVVPAGGSYFMISRSLGPEFGGAVGLCFYLGTTFAAAMYILGAIEILLTYIAPPAAIFYPSGAHDTSNATLNNMRVYGTIFLTFMTLVVFVGVKYVNKFASLFLACVIISILSIYAGGIKSIFDPPVFPVCMLGNRTLSRDQFDICAKTAVVDNETVATQLWSFFCHSPNLTTDSCDPYFMLNNVTEIPGIPGAAAGVLQENLWSAYLEKGDIVEKHGLPSADAPSLKESLPLYVVADIATSFTVLVGIFFPSVTGIMAGSNRSGDLRDAQKSIPVGTILAIITTSLVYFSSVVLFGACIEGVVLRDKYGDGVSRNLVVGTLAWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHGKVNGEPTWALLLTALIAELGILIASLDMVAPILSMFFLMCYLFVNLACAVQTLLRTPNWRPRFKYYHWALSFLGMSLCLALMFVSSWYYALVAMLIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARYALLRLEEGPPHTKNWRPQLLVLLKLDEDLHVKYPRLLTFASQLKAGKGLTIVGSVIQGSFLESYGEAQAAEQTIKNMMEIEKVKGFCQVVVASKVREGLAHLIQSCGLGGMRHNSVVLGWPYGWRQSEDPRAWKTFIDTVRCTTAAHLALLVPKNIAFYP-SNHERYLEGHIDVWWIVHDGGMLMLLPFLLRQHKVWRKCRMRIFTVAQMDDNSIQMKKDLAVFLYHLRLEAEVEVVEMHNSDISAYTYERTLMMEQRSQMLRQMRLTKTEREREAQLVKDR-------------------------HSALRLESLYSDEEDESAVG-ADKIQMTWTRDKYMTETWDPSHAPDNFRELVH------IKPDQSNVRRMHTAVKLNEVIVTRSHDARLVLLNMPGPPR--NSEGDENYMEFLEVLTEGLERVLLVRGGGREVITIYS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QBW2-1", "uniprot_id": "F1QBW2_DANRE", "id": "F1QBW2-1", "name": "", "aln": "MPHFTVVPVQDNSPSNYDSLEGINWVDYRDTGQGEYPGHGDTVSSDGHGNHKEDSPFLSSSDSASKRNDFYDRNLALFEEELDIRPKVSSLLSRLVNYTNVTQGAKEHEEAESADASRRQAPKSPNMGTLMGVYLPCLQNIFGVILFLRLTWIVGTAGVVQSFLIVLMCCSCTMLTAISMSAIATNGVVPAGGAYFMISRSLGPEFGGAVGLCFYLGTTFAAAMYILGAIEIFLKYLIPQAAIFHPADIHAGNGAMLNNMRVYGTICLSLMAVVVFVGVKYVNKLASLFLACVIISIVSIYAGAVKSIFHPPEFPICMLGNRTLVRDLFDVCGKTVVVGNETVPSKLWKNFCTSDNISSAHCDEYFFHNNVTEIKGIPGLASGIIKENMWGDYMEKGQILEKAKLPSVDVHGSMETFGFYVSADIATSFTLLVGIFFPSATGIMAGSNRSGDLRDAQKSIPIGTILAITTTSLVYFSSVVLFGACIEGVVLRDKFGDAVSKNLVVGTLSWPSPWVIVIGSFFSTVGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHGKANGEPTWALLLTGLIAELGILIASLDMVAPILSMFFLMCYLFVNLACAVQTLLRTPNWRPRFRYYHWALSFLGMSMCLALMFISSWYYAIVAMGIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARYSLLRLEAGPPHTKNWRPQLLVLLKLDEDLHVKYPRLLTFASQLKAGKGLTIVGSVIQGNFLECYGETQASEQAIKNMMEIERVKGFCQVVVASKVREGIAHLIQSCGLGGMKHNTVVMGWPYGWRQSEDPRAWKTFINTVRCTTAAHLALMVPKNVSFYP-SNHERFTDGYIDVWWIVHDGGMLMLLPFLLKQHKVWRKCKMRIFTVAQMDDNSIQMKKDLATFLYQLRLEAEVEVVEMHDSDISAYTYERTLMMEQRSQMLKQMRLSSAERDREAQLVKDR-------------------------HSLIRMGSLYSDEEEETIEILPEKNQMTWTSEKIEAERRNRNNAPENFRELIS------IKPDQSNVRRMHTAVKLNEVIVNKSHDARLVLLNMPGPPR--NQEGDENYMEFLEVLTEGLERVLLVRGGGREVITIYS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4LGD3-1", "uniprot_id": "A0A0B4LGD3_DROME", "id": "A0A0B4LGD3-1", "name": "", "aln": "-------MQSNSAKDDSDEMEIIPSEHNGTVHETK--------NEDSGDIHRAEENQKSSID----------PNLYLYDDDLETRPHISTFISSIANYENTIPAATDPDAKPAAPSAR--------MGTLIGVFLPCIQNIFGVILFIRLTWVVGTAGAVCGFLIVLTCCCVTMLTAISMSAIATNGVVPAGGSYFMISRSLGPEFGGAVGMLFYTGTTLAAAMYIVGAVEIVLTYMAPWASIFG--DFTKDADAMYNNFRVYGTLLLIFMGLIVFLGVKFVNKFATVALACVILSIIAVYVGIFDNIHGNEKLYMCVLGKRLLKDIPLENCTK--------EDSFLRDIYCPDG-----KCEEYYLANNVTKVKGIKGLASGVFYDNIFPSFLEKGQFIS-YGKSAIDIENTSGESYNQIMADITTSFTLLIGIFFPSVTGIMAGSNRSGDLADAQKSIPIGTICAILTTSTVYLSSVMFFAGTVDNLLLRDKFGQSIGGKLVVANIAWPNQWVILIGSFLSTLGAGLQSLTGAPRLLQAIARDEIIPFLAPFAKSSKRGEPTRALLLTIVICQCGILLGNVDLLAPLLSMFFLMCYGFVNLACAVQTLLRTPNWRPRFKFYHWSLSLIGLTLCISVMIMTSWYFALIAMGMAIIIYKYIEYRGAEKEWGDGIRGMALTAARYSLLRLEEGPPHTKNWRPQILVLSKLNDNLLPKYRKIFSFATQLKAGKGLTICVSVIKGDHTKITNKAVDAKATLRKYMTDEKVKGFCDVLVAQQIGEGLSSVIQTIGLGGMKPNTVIIGWPYSWRQ-EGRNSWKTFIQTVRTVAACHMALMVPKGINFYPESNHK--IGGNIDIWWIVHDGGLLMLLPFLLKQHRTWRNCKLRIFTVAQIEDNSIQMKKDLKTFLYHLRIEADVEVVEMNNSDISAYTYERTLMMEQRNQMLRALGLNKKENSKVVQTIMDYKETPSDNKMSLVQTIVDHHYDATKTASKVRFADPTIEETQHHDSQNDEKRNSIDLDGPENADTPETTSNKDESTEKADGDFKSSVKPDEFNVRRMHTAIKLNEVIVEKSQDAQLVIMNLPGPPREVRAERERNYMEFLEVLTEGLEKVLMVRGGGREVITIYS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. .: *.:* : . : . ..*. . *: .. .. : ** *::::*: **::*:::. :..* * .*.: : :. . * ****:**:***:*********:****:*****.: .:**** **. *:*******************:*****************: ** ***:******:**:**.*.*: * *:** . .* **:*****: * :* ::**:***:***:*:: *****:**:::*.* ... . : :*:**:* * :: * * : * :* . *: *:: ****:: ** * *:*:: :*:: ::***:.:. .: * . : ***:****:*:******.************* *******:*** ** *** **:***::*.. ::.::****:*:.:. :***..::**. ***::***:** ******************:*:***** *.:.. .**** ***** :*.: ***:..:*::**:********* *********************::***:**::*:::*:::*:::***:*::** :* :*******:************::*:****:***** ***********:*** **:::* ** ::::**:********** ***:*.. : .:: :: :::: * *:*****:*:**.:: **:: :**: *****: *:*::****.*** *. .:*****:*** .:*.*:**:***.: *** ***: * **:********:********:**:.*::*::*******::********** ***:**:**:******::*****************.***: : *.. *..: .* : * * :*: . :* :. :* : :: : . :: * :***: ********:******* :*:**:**::*:****: . * :.**************:**:*************", "identical_positions": 565, "similar_positions": 286, "identity": "50.04%" }, { "cls_id": "homologset.agr.MGI:1309466", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z1B2-1", "uniprot_id": "GSTM5_RAT", "id": "Q9Z1B2-1", "name": "Glutathione S-transferase Mu 5", "aln": "MSCSKSMVLGYWDIRGLAHAIRMLLEFTDTSYEEKQYTCGEAPDYDRSQWLDVKFKLDLDFPNLPYLMDGKNKITQSNAILRYIARKHNMCGDTEEEKIRVDIMENQIMDFRMQLVRLCYNSNHESLKPQYLEQLPAQLKQFSLFLGKFTWFAGEKLTFVDFLTYDVLDQNRMFEPKCLDEFPNLKAFMCRFEALEKIAAFLQSDRCFKMPINNKMAKWGNKSIC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P48774-1", "uniprot_id": "GSTM5_MOUSE", "id": "P48774-1", "name": "Glutathione S-transferase Mu 5", "aln": "MS-SKSMVLGYWDIRGLAHAIRMLLEFTDTSYEEKRYICGEAPDYDRSQWLDVKFKLDLDFPNLPYLMDGKNKITQSNAILRYIARKHNMCGDTEEEKIRVDIMENQIMDFRMQLVRLCYNSNHENLKPQYLEQLPAQLKQFSLFLGKFTWFAGEKLTFVDFLTYDVLDQNRIFEPKCLDEFPNLKAFMCRFEALEKIAAFLQSDRFFKMPINNKMAKWGNKCLC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P21266-1", "uniprot_id": "GSTM3_HUMAN", "id": "P21266-1", "name": "Glutathione S-transferase Mu 3", "aln": "MSCESSMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPYLLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDHEKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLDEFPNLKAFMCRFEALEKIAAYLQSDQFCKMPINNKMAQWGNKPVC", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** ..*****************:************:* *****************************:************************:**********:***:**** **:****.*:**.*******:**.******:*****:****************:*****:*:*************************:****: *********:**** :*", "identical_positions": 196, "similar_positions": 23, "identity": "87.11%" }, { "cls_id": "homologset.agr.MGI:1309467", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P09488-1", "uniprot_id": "GSTM1_HUMAN", "id": "P09488-1", "name": "Glutathione S-transferase Mu 1", "aln": "MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNLKDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P46439-1", "uniprot_id": "GSTM5_HUMAN", "id": "P46439-1", "name": "Glutathione S-transferase Mu 5", "aln": "MPMTLGYWDIRGLAHAIRLLLEYTDSSYVEKKYTLGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQSNAILRYIARKHNLCGETEEEKIRVDILENQVMDNHMELVRLCYDPDFEKLKPKYLEELPEKLKLYSEFLGKRPWFAGDKITFVDFLAYDVLDMKRIFEPKCLDAFLNLKDFISRFEGLKKISAYMKSSQFLRGLLFGKSATWNSK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O35660-1", "uniprot_id": "GSTM6_MOUSE", "id": "O35660-1", "name": "Glutathione S-transferase Mu 6", "aln": "MPVTLGYWDIRGLGHAIRLLLEYTETGYEEKRYAMGDAPDYDRSQWLNDKFKLDLDFPNLPYLIDGSHKVTQSNAILRYLGRKHNLCGETEEERIRVDILEKQVMDTRIQMGMLCYSADFEKRKPEFLKGLPDQLKLYSEFLGKQPWFAGDKITFADFLVYDVLDQHRMFEPTCLDAFPNLKDFMARFEGLRKISAYMKTSRFLPSPVYLKQATWGNE", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**: *********.**********::.* **:*::*************:****.************:**:******* *:.************:*******:*.**.:::: :**..:*** **::*: **::**********:*****:****.***.***** :*:***.***** *****::*****.*******:*:** :: * *.*..:", "identical_positions": 155, "similar_positions": 49, "identity": "71.1%" }, { "cls_id": "homologset.agr.MGI:1309468", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O09165-1", "uniprot_id": "CASQ1_MOUSE", "id": "O09165-1", "name": "Calsequestrin-1", "aln": "MRATDRMGARAVSELRLALLFVLVLGTPRLGVQGEDGLDFPEYDGVDRVINVNAKNYKNVFKKYEVLALLYHEPPEDDKASQRQFEMEELILEL-----------AAQVLE---DKGVGFGLVDSEKDAAVAKKLGLTEEDSVYVFKGDEVIEYDGEFSADTLVEFLLDVLEDPVELIEGERELQAFENIEDEIKLIGYFKSKDSEHYKAYEDAAEEFHPYIPFFATFDSKVAKKLTLKLNEIDFYEAFMEEPMTIPDKPNSEEEIVSFVEEHRRSTLRKLKPESMYETWEDDLDGIHIVAFAEEADPDGYEFLETLKAVAQDNTENPDLSIIWIDPDDFPLLVPYWEKTFDIDLSAPQIGVVNVTDADSIWMEMDNEEDLPSADELEDWLEDVLEGEIN-----------TEDDDDDDDDDDDDDDDDD-----------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P19633-1", "uniprot_id": "CASQ1_RAT", "id": "P19633-1", "name": "Calsequestrin-1", "aln": "MRATDRMGARAVSKLRLALLFVLVLGTPRSGVQGEDGLDFPEYDGVDRVINVNAKNYKNVFKKYEVLALLYHEPPEDDKASQRQFEMEELILEL-----------AAQVLE---DKGVGFGLVDSEKDAAVAKKLGLTEEDSVYVFKGDEVIEYDGEFSADTLVEFLLDVLEDPVELIEGERELQAFENIEDEIKLIGYFKSKDSEHYKAYEDAAEEFHPYIPFFATFDSKVAKKLTLKLNEIDFYEAFMEEPVTIPDKPNSEEEIVSFVEEHRRSTLRKLKPESMYETWEDDLDGIHIVAFAEEADPDGYEFLETLKAVAQDNTENPDLSIIWIDPDDFPLLVPYWEKTFDIDLSAPQIGVVNVTDADSIWMEMDDEEDLPSAEELEDWLEDVLEGEIN-----------TEDDDDDDDDDDDDDDDDDD----------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P31415-1", "uniprot_id": "CASQ1_HUMAN", "id": "P31415-1", "name": "Calsequestrin-1", "aln": "MSATDRMGPRAVPGLRLALLLLLVLGTPKSGVQGQEGLDFPEYDGVDRVINVNAKNYKNVFKKYEVLALLYHEPPEDDKASQRQFEMEELILEL-----------AAQVLE---DKGVGFGLVDSEKDAAVAKKLGLTEVDSMYVFKGDEVIEYDGEFSADTIVEFLLDVLEDPVELIEGERELQAFENIEDEIKLIGYFKSKDSEHYKAFEDAAEEFHPYIPFFATFDSKVAKKLTLKLNEIDFYEAFMEEPVTIPDKPNSEEEIVNFVEEHRRSTLRKLKPESMYETWEDDMDGIHIVAFAEEADPDGFEFLETLKAVAQDNTENPDLSIIWIDPDDFPLLVPYWEKTFDIDLSAPQIGVVNVTDADSVWMEMDDEEDLPSAEELEDWLEDVLEGEIN-----------TEDDDDDDDD--------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IKE0-1", "uniprot_id": "A0A0R4IKE0_DANRE", "id": "A0A0R4IKE0-1", "name": "Calsequestrin", "aln": "--------------MKWNLVFLGLLLTFGQLSWGQKGMDIPEYDGKDRVHELNAKNYKSVMKKYDVMVVYYHEHVGSSKVAQKQFQIEELALEL-----------AAQVLADFDDEDIGIGLLDEKTDKAVAKKLGLDEADSIFIFIEDEVIEYDGELAADTLVEFIYDVIEDPVEIIGNVREMKGFNNIEEDIKLVGFFKSAKSDHYHEYEDAAEEFHPHIKFFATFNPKVALKLGLKLNEVDFYEPFMDKPVVIPGKPYSEKELVRFIEDNDRPTLRKMQPHNMYEIWEDALDGEHIIAFAEEGDPDGFEFLEIVKEVAEDNTENPDLSIIWIDPDDFPLLVHYWEKTFDIDLSSPQIGVVEVDDAESIWFDMDDD-DMPTVDELEDWLEDVLENKIDPDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDNDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F6P0J3-1", "uniprot_id": "F6P0J3_DANRE", "id": "F6P0J3-1", "name": "Calsequestrin", "aln": "--------------MKWRWVIWGVLLSLGYQCWSETGLDFPEYDGKDRVHQLTAKNYKSVMKKYDVMVIYLHKPVGEDRMARKQFEVEELALELLTSPAALTYQLAAQVLDGLDDEDIGFGLVDSKKDRAVAKKLGMLEVDSIYIFADDEIIEYDGALAADTLLEFLYDVIEDPVEIISNDRELKGFHNIEEDMKLMGFFKSNKSPYFIEYDDAAEEFHPFIKFFATFEPKIAKKLNLKMNEVDFYEPFMDKPVTIPGKPYMEDDIINFIEDHDRPTLRKLEPHSMYEIWEDDINGQHIVAFAEESDPDGYEFLEILKEVAQENTENPELSIIWIDPDDFPLMVPYWEKTFGIDLSSPQIGVVDVENADSVWMEMDDEEHMPTADQLDAWIEDVMTGNINPNDENQYHDDDDEDDDDHDDEDDDDHDDDDDDEDEDHDDDDDDEDLDDDDDEDLDEDDDDDEDHDDDD---------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: :: :* : .: *:*:***** *** ::.*****.*:***:*:.: *: ..: :::**::*** *** ***** *:.:*:**:*.:.* *******: * **:::* **:***** ::***::**: **:*****:* . **::.*.***:::**:*:*** .* :: ::********.* *****:.*:* ** **:**:****.**::*:.**.** *.::: *:*:: *.****::*..*** *** ::* **:*****.****:**** :* **::*****:*************:* ******.****:******:* :*:*:*::**:: .:*:.::*: *:***: .:*: :****.**: ", "identical_positions": 206, "similar_positions": 122, "identity": "35.58%" }, { "cls_id": "homologset.agr.MGI:1309469", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P51868-1", "uniprot_id": "CASQ2_RAT", "id": "P51868-1", "name": "Calsequestrin-2", "aln": "MKRIYLLVVGLYLLSFSRAEEGLNFPTYDGKDRVVSLSEKNLKQVLKRYDLLCLYYHEPVSSDKVAQKQFQLKEIVLELVAQVLEHKNIGFVMVDSRKEAKLAKRLGFSEEGSLYVLKGGRTIEFDGEFAADVLVEFLLDLIEDPVEIVNNKLEVQAFERIEDQIKLLGFFKNEDSEYYKAFQEAAEHFQPYIKFFATFDKGVAKKLSLKMNEVGFYEPFMDEPSVIPNKPYTEEELVEFVKEHQRPTLRPLRPEDMFETWEDDLNGIHIVAFAEKSDPDGYEFLEILKQVARDNTDNPDLSILWIDPDDFPLLVAYWEKTFKIDLFKPQIGVVNVTDADSVWMEIPDDDDLPTAEELEDWIEDVLSGKINTEDDDNEDEDDDGDNDNDDDDDDDDN--SDEDNDDSDDDDDDDE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O09161-1", "uniprot_id": "CASQ2_MOUSE", "id": "O09161-1", "name": "Calsequestrin-2", "aln": "MKRIYLLMVGVYLLSLSGAEEGLNFPTYDGKDRVVSLSEKNLKQMLKRYDLLCLYYHEPVSSDKVSQKQFQLKEIVLELVAQVLEHKNIGFVMVDSRKEAKLAKRLGFSEEGSLYVLKGDRTIEFDGEFAADVLVEFLLDLIEDPVEIVNNKLEVQAFERIEDQTKLLGFFKNEDSEYYKAFQEAAEHFQPYIKFFATFDKAVAKKLSLKMNEVGFYEPFMDEPNVIPNKPYTEEELVEFVKEHQRPTLRRLRPEDMFETWEDDLNGIHIVAFAEKSDPDGYEFLEILKQVARDNTDNPDLSILWIDPDDFPLLVAYWEKTFKIDLFKPQIGVVNVTDADSIWMEIPDDDDLPTAEELEDWIEDVLSGKINTEDDDNEDEDDDGDDNDDDDDDDDDNDNSDEDNEDSDDDDDDDE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14958-1", "uniprot_id": "CASQ2_HUMAN", "id": "O14958-1", "name": "Calsequestrin-2", "aln": "MKRTHLFIVGIYFLSSCRAEEGLNFPTYDGKDRVVSLSEKNFKQVLKKYDLLCLYYHEPVSSDKVTQKQFQLKEIVLELVAQVLEHKAIGFVMVDAKKEAKLAKKLGFDEEGSLYILKGDRTIEFDGEFAADVLVEFLLDLIEDPVEIISSKLEVQAFERIEDYIKLIGFFKSEDSEYYKAFEEAAEHFQPYIKFFATFDKGVAKKLSLKMNEVDFYEPFMDEPIAIPNKPYTEEELVEFVKEHQRPTLRRLRPEEMFETWEDDLNGIHIVAFAEKSDPDGYEFLEILKQVARDNTDNPDLSILWIDPDDFPLLVAYWEKTFKIDLFRPQIGVVNVTDADSVWMEIPDDDDLPTAEELEDWIEDVLSGKINTEDDD---EDDDDDDNSDE-----------EDNDDSDDDDDE--", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** :*::**:*:** . ***********************:**:**:*****************:********************* *******::*******:***.******:***.****************************:..************ **:****.*********:******************.************.********* .************************ ****:***********************************************************************:*************:********************************** ****.*::.*: ***:*******: ", "identical_positions": 356, "similar_positions": 35, "identity": "85.78%" }, { "cls_id": "homologset.agr.MGI:1309472", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9R0Q2-1", "uniprot_id": "LT4R1_RAT", "id": "Q9R0Q2-1", "name": "Leukotriene B4 receptor 1", "aln": "MAANTTSTAATSSPGGMSLSLLPIVLLSVALVVGLPGNSFVVWSILKRMQKRSVTALLVLNLALADLAVLLTAPFFLHFLARGTWSFEVTGCRLCHYVCGVSMYASVLLITIMSLDRSLAVARPFVSQKVRTKAFARWVLAGIWVVSFLLAIPVLVYRTVT-PKNKTLICDSRYPSDGHKVFHLLFEAITGFLLPFLAVVASYSDIGRRLQARRFRRSRRTGRLVVLIILAFAAFWLPYHLVNLVEAGRTLAGWDKNS-PAGQRLKLARYVLIALAFLSSSVNPVLYACAGGGLLRSAGVGFVVKLLEGTGSEVSSTRRGGTLVQTPKATPTCPEPGPTDSFMTSSTPPESSK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88855-1", "uniprot_id": "LT4R1_MOUSE", "id": "O88855-1", "name": "Leukotriene B4 receptor 1", "aln": "MAANTTSPAAPSSPGGMSLSLLPIVLLSVALAVGLPGNSFVVWSILKRMQKRTVTALLVLNLALADLAVLLTAPFFLHFLARGTWSFREMGCRLCHYVCGISMYASVLLITIMSLDRSLAVARPFMSQKVRTKAFARWVLAGIWVVSFLLAIPVLVYRTVK-WNNRTLICAPNYPNKEHKVFHLLFEAITGFLLPFLAVVASYSDIGRRLQARRFRRSRRTGRLVVLIILAFAAFWLPYHLVNLVEAGRTVAGWDKNS-PAGQRLRLARYVLIALAFLSSSVNPVLYACAGGGLLRSAGVGFVVKLLEGTGSEVSSTRRGGTLVQTPKDTPACPEPGPTDSFMTSSTIPESSK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15722-1", "uniprot_id": "LT4R1_HUMAN", "id": "Q15722-1", "name": "Leukotriene B4 receptor 1", "aln": "--MNTTSSAAPPSLGVEFISLLAIILLSVALAVGLPGNSFVVWSILKRMQKRSVTALMVLNLALADLAVLLTAPFFLHFLAQGTWSFGLAGCRLCHYVCGVSMYASVLLITAMSLDRSLAVARPFVSQKLRTKAMARRVLAGIWVLSFLLATPVLAYRTVVPWKTNMSLCFPRYPSEGHRAFHLIFEAVTGFLLPFLAVVASYSDIGRRLQARRFRRSRRTGRLVVLIILTFAAFWLPYHVVNLAEAGRALAGQAAGLGLVGKRLSLARNVLIALAFLSSSVNPVLYACAGGGLLRSAGVGFVAKLLEGTGSEASSTRRGGSLGQTARSGPAALEPGPSESLTASSPLKLNELN", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ****.**..* * :***.*:******.********************:****:***********************:***** **********:********** *************:***:****:** *******:***** ***.**** :.. :* ..**.. *:.***:***:*****************************************:*********:***.****::** . .*:** *** *********************************.*********.*******:* **.: *:. ****::*: :**. .. ", "identical_positions": 266, "similar_positions": 50, "identity": "75.14%" }, { "cls_id": "homologset.agr.MGI:1309478", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6G4X5-1", "uniprot_id": "A0A8I6G4X5_RAT", "id": "A0A8I6G4X5-1", "name": "Bromodomain adjacent to zinc finger domain protein 1A", "aln": "MPLLHRKPFVRQKPPGD---LRPDEEVFYCKVTNEIFRHYDDFFERTILCNSLVWSCAVTGRPGLTYQEALESERKAKQDLQSFPEPLIIPVLYLTNLTHRSRLHEICDDIFAYIKDRYFVEETVEVIRNNGTRLQCRILEVLPPLHQNGFANGHMSS-VDGETIVISDSDDSETQSS--SFQHGKKKDAIDPLLFRYRVQPTKKEMYESAVVKATQISRRKHLFSRDKLKLFLKQHCEPQDGVIKIKASSFSTYNIAEQD-FSYFFPDDPPTFIFSPANRRRGRPPKRISFGQEDNIASKQTIARCRSKAIKERDKLLKQEEMRALAFEKAKLKREKADALEARKREREDREKKREELKKIVEEERLKKKEEKERLKIEREKEREKLREEKRKYMEYLKQWSKPREDMECDDLKELPEPTPVKTRLPPEVFGDALMVLEFLNAFGELFDLQDEFPEGVTL-EVLEEALVGNDSEGPLCELLFFFLTAIFQAMAEEEEEVAKEQITDADTK--------------------------------GCSLKSLDLDSCTLSEILRLHILASGADVTSANAKYRYQKRGGFDATDDACMELRLSNPSLVKKLSSTAVYDLTPGEKMKILHALCGKLLTLVSTRDFIEDYVDVLRQAKQEFRELKAEQHRKEREATAARIRRRKEEKLKEQEQKMKEKQEKLKEDEQRTSAAD--LGEEGREDFDTSADSKEIERKDLDPDVVTEDEDDLGSHKRSRRGKAGQTAVKQCIKQEEMNYCIKQEPLTADAEEALRQEHQRKEKELLDKIQSAIACTNIFPLGRDRLYRRYWVFPSIPGLFIEEDYSGLTEDMLLPRPSSFHSNAQPHSPRVSIKTEESFMSESTSSLDQGPFDDSLLLPKPVHKPNRWCFYSSCEQLDQLIEALNSRGHRESALKETLLQEKSRICAQLAHFSEEKFHFSDKPQADSKPVSSRGRS-AACDTSQM------SAERQLELRLRDFLLDIEDRIYQGTLGAIKVTDRQVWRSALENGRYELLS-----------EESKENGVSKAVNDDVEEMEI-EQARVIVRDRLLGLKTETPSTVSTSTSTPQSVSN-------VVHYLATALFQIEQGIERRFLKAPL---------------------------DGSDSGRSYKTVLDRWRESLLSSASLSQVFLHLSTLDRSVMWSKSILNARCKICRKKGDAENMVLCDGCDRGHHTYCVRPKLKTVPDGDWFCPECRP--------KQRSRRLSSRQRPSLESDEEMEEGMEGDDGEVDDDDEDGQSEEEEYEVEQDEEDSDEEEALSPPKRGRPQVRLPIKTRGRFGPSFSSRSQRQDPGRYPSRSQQSTPKTTASKTAGRNLRKTRSAPPTETRSLRLGSRSTRHSPNALQADVFVELLSPRGKRRVRKSADNTPEHSPSLTNLRVSTSRPSVQLIPLNSAERLSLQDSESKRRGRKRQSTESSPVPLN---RRSSGRQGGVHELS---AFEQLVVELVRHDDSWPFLKLVSKIQVPDYYDIIKKPIALNIIREKVNKCEYKLASEFIEDIELMFSNCFEYNPRNTSEAKAGTRLQAFFHIQAQKLGLHVSPSNVDQASTPLAAKKSRI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88379-1", "uniprot_id": "BAZ1A_MOUSE", "id": "O88379-1", "name": "Bromodomain adjacent to zinc finger domain protein 1A", "aln": "MPLLHRKPFVRQKPPGD---LRPDEEVFYCKVTNEIFRHYDDFFERTILCNSLVWSCAVTGRPGLTYQEALESERKARQNLQSFPEPLIIPVLYLTNLTRRSRLHEICDDIFAYVKDRYFVEETVEVIRNNGTRLQCRILEVLPPLHQNGFANGHLSS-ADGETIVISDSDDSETQSS--SFHHGKKKDAIDPLLFRYRVQPTKKEMYESAVVKATQISRRKHLFSRDKLKLFLKQHCEAQDGVIKIKASSFSAYNIAEQD-FSYFFPDDPPTFIFSPANRRRGRPPKRISFGQEDSIASKQTAARYRNKAIKERDKLLKQEEMRALAFEKAKLKRERADALEARKREKEDKEKKREELKKMVEEERLKKKEEKERLKIEREKEREKLREEKRKYMEYLKQWSKPREDMECDDLKELPEPTPVKTRLPPEVFGDALMVLEFLNAFGELFDLQDEFPEGVTLAEVLEEALVGNDSEGPLCELLFFFLTAIFQAMAEEEEEVAKEQITDADTKDLTEALDEDADPTKSALSAVAALAAAWPQLHQGCSLKSLDLDSCTLSEILRLHILASGADVTSANAKYRYQKRGGFDATDDACMELRLSNPSLVKKLSSTSVYDLTPGEKMKILHALCGKLLTLVSTRDFIEDYVDVLRQAKQEFRELKAEQHRKEREATAARIRRRKEEKLKEQEQKMKEKQEKLKEDEQRNSAAVPGYGEEEREDFDTSTENKNIEQKDLDPDVVTEDEDDPGSHKRSRRGKVGQTAVKQCIKQEEMNYCIKQEPLSADAEEALRQEQQQKEKELLDKIQSAIACTNIFPLGRDRLYRRYWIFPSIPGLFIEEDYSGLTEDMLLPRPSSFHNNAQPRDPQVSIKTEESFLSESTSSLDQGPFDDSVLLPKPVHKPNRWCFYSSCAQLDQLIDALNSRGHRESALKETLLQEKSRICAQLAHFSEEKFHFSDKPQADSKPVSSRGRSSGACDISQM------SAERQLELRLRDFLLDIEDRIYQGTLGAIKVTDRQVWRSALENGRYELLS-----------EESKENGVIKTVNEDVEEMEM-EQARVIVRDRLLGIKTETPSTISTSASTPQSVSN-------VVHYLALALFQIEQGIERRFLKAPL---------------------------DGNDSGRSYKTVLDRWRESLLSSASLSQVFLHLSTLDRSVMWSKSILNARCKICRKKGDAENMVLCDGCDRGHHTYCVRPKLKAVPDGDWFCPECRP--------KQRSRRLSSRQRPSLESDEEMEEGMEDDDDEVDDDDEEGQSEEEEYEVEQDEEDSDDDEALSPPKRGRPQVRLPIKTKGRFGPSFPSRSQRQDPGRYPSRSQQSTPKNTA-KSASKNLRKTRSAPPTETRSLRVGSRSTRHSPSALQ-DVFVELLSPHSKRRGRKGADHTPEHSPSFTNFRVSTSRSSRQLIPLNTAESLSLQHSESKRRGRKRQSTESSPVPLN---RRSSGRQGGVHELS---AFEQLVVELVRHDDSWPFLKLVSKIQVPDYYDIIKKPIALNIIREKVNKCEYKLASEFIDDIELMFSNCFEYNPRNTSEAKAGTRLQAFFHIQAQKLGLHVSPSTVDQVSTPLAAKKSRI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NRL2-1", "uniprot_id": "BAZ1A_HUMAN", "id": "Q9NRL2-1", "name": "Bromodomain adjacent to zinc finger domain protein 1A", "aln": "MPLLHRKPFVRQKPPAD---LRPDEEVFYCKVTNEIFRHYDDFFERTILCNSLVWSCAVTGRPGLTYQEALESEKKARQNLQSFPEPLIIPVLYLTSLTHRSRLHEICDDIFAYVKDRYFVEETVEVIRNNGARLQCRILEVLPPSHQNGFANGHVNS-VDGETIIISDSDDSETQSC--SFQNGKKKDAIDPLLFKYKVQPTKKELHESAIVKATQISRRKHLFSRDKLKLFLKQHCEPQDGVIKIKASSLSTYKIAEQD-FSYFFPDDPPTFIFSPANRRRGRPPKRIHISQEDNVANKQTLASYRSKATKERDKLLKQEEMKSLAFEKAKLKREKADALEAKKKEKEDKEKKREELKKIVEEERLKKKEEKERLKVEREKEREKLREEKRKYVEYLKQWSKPREDMECDDLKELPEPTPVKTRLPPEIFGDALMVLEFLNAFGELFDLQDEFPDGVTL-EVLEEALVGNDSEGPLCELLFFFLTAIFQAIAEEEEEVAKEQLTDADTKDLTEALDEDADPTKSALSAVASLAAAWPQLHQGCSLKSLDLDSCTLSEILRLHILASGADVTSANAKYRYQKRGGFDATDDACMELRLSNPSLVKKLSSTSVYDLTPGEKMKILHALCGKLLTLVSTRDFIEDYVDILRQAKQEFRELKAEQHRKEREEAAARIRKRKEEKLKEQEQKMKEKQEKLKEDEQRNSTADISIGEEEREDFDTSIESKDTEQKELDQDMVTEDEDDPGSHKRGRRGKRGQNGFKEFTRQEQIN-CVTREPLTADEEEALKQEHQRKEKELLEKIQSAIACTNIFPLGRDRMYRRYWIFPSIPGLFIEEDYSGLTEDMLLPRPSSFQNNVQSQDPQVSTKTGEPLMSESTSNIDQGPRDHSVQLPKPVHKPNRWCFYSSCEQLDQLIEALNSRGHRESALKETLLQEKSRICAQLARFSEEKFHFSDKPQPDSKPTYSRGRSSNAYDPSQM------CAEKQLELRLRDFLLDIEDRIYQGTLGAIKVTDRHIWRSALESGRYELLS-----------EENKENGIIKTVNEDVEEMEIDEQTKVIVKDRLLGIKTETPSTVSTNASTPQSVSS-------VVHYLAMALFQIEQGIERRFLKAPL---------------------------DASDSGRSYKTVLDRWRESLLSSASLSQVFLHLSTLDRSVIWSKSILNARCKICRKKGDAENMVLCDGCDRGHHTYCVRPKLKTVPEGDWFCPECRP--------KQRSRRLSSRQRPSLESDEDVEDSMGGEDDEVDGDEEEGQSEEEEYEVEQDEDDSQEEEEVSLPKRGRPQVRLPVKTRGKLSSSFSSRGQQQEPGRYPSRSQQSTPKTTVSSKTGRSLRKINSAPPTETKSLRIASRSTRHSHGPLQADVFVELLSPRRKRRGRKSANNTPENSPNFPNFRVIATKSSEQSRSVNIASKLSLQESESKRRCRKRQSPEPSPVTLG---RRSSGRQGGVHELS---AFEQLVVELVRHDDSWPFLKLVSKIQVPDYYDIIKKPIALNIIREKVNKCEYKLASEFIDDIELMFSNCFEYNPRNTSEAKAGTRLQAFFHIQAQKLGLHVTPSNVDQVSTPPAAKKSRI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13A7N8-1", "uniprot_id": "A0AB13A7N8_DANRE", "id": "A0AB13A7N8-1", "name": "Bromodomain adjacent to zinc finger domain protein 1A", "aln": "MPLLHKKPFVRQKPPAD---LRPDEEVFLCKYTHEIFRTYDEFFERTILCNSLVWSCAVTGKPGLTYQEALESEKKARLSLQNFPNALAVPLLHLTALTHRSRLHEICDDVYAYVKDRFFPGEMVDITSRS-TRQLCKILEVIPP-YSNGAVNGHTKHRIEGDSIVISDSDDEPTVTSPKTPSNGKKKKAINPSSFKYRVQPVSPEACEPVIVKVAQMSRKKSIFSRDRLKLLLKQHCEPMHGTIRVKPSSALQYKLAEHS-FSHFFPDEPPVFTFSPPGKGRGRPPN--------------NASSTEINYIEEKLKLMQQKEQ---MMSMEKFRKERDDLIEAKKKEKEDKEKKKEEMKRILEEEKLRRKEERERMKVEKEREREKLKEEKKKYAERLKLWSKPREDMECDDLKELPKPIPVKTRLPPELFGDALMVLEFLHAFGELFDLKDEFPDGVTL-EVLEEAVVGSDPEGPLCELLFFFLSAIFQALAEEQEEVAKDQLAEDLSE----ALDDDADPTQSAISAVASLAAAWPQLHQGCSLKQLDLDSCTLSEILRLHILSSGADCGFTNAKFRYQKQGGFGSTDDPCVELRLSNHGLLKKLSCTSVYDLLPGEKLKILHSMCGKLLTLVSTRDFIEDNADEQRAAKQELRELKAEQHRREREEAAERVRKRKEEKLREQELKLKEKHERLKEEAKNG-------GQLAGEEMDTSTESQ-----EGHAEQHTEDEEEQPAKSKKVKKTNGTT------KEKPSGEVEMKDNLSPEE----LQLQQLKERELLERIQQAMACTYILPLGRDRLYRRYWIFPSAGALFVEDDFFGLTEDMLEPRPTPEPKIEEVLSAESPVKTDG-ATEELVLVQNTSP---------PVNRPNQWYFYSTTEEVEQLIEALNPRGLRESSLKETLTLERGRIFQLMESNAAQRYHHSGESLPETKGSSGKAKVGPQSTVP---------AECFMENRLRDLLLDIEDRIYQGTLGSIKVMERNSWRAALENGNYELLD-----------PDFKEYGLT---DREEEPMEIEENHR--VKDRLQELKVEGHSATSTSVSTPQPVNN-------VVHCLAHALAQVEQGIERKFLKAPLGDEDAKKDQKAKKKDKKKDDDQSSEKDDGSESGRQVKTVQERWRESLLACTSLSQVFLHLSTLERSVAWAKSILNTRCKVCRRKGDAENMLLCDGCGRGYHIFCVRPKLKAVPSEDWFCPECRP--------KQRLNRINSRQRSSVDSEEEMED-----EEESEEEDEEESEEEEESEEEQSEEEE-------VPKKAAVKLPLQNNKGGRS----NSKSKQAESANSTSRSQQNTPKQSQPANKGGSKNSGKKATPVSNG--KPPSRAGNRSSARLS----LEVISTNDTTG--KSEQSSPAAGNAESRKRPITAEVSP----------------------KSKIILAPTTTSSS---RRSSGRNLGVHELS---ACELLSVDLVRHEDSWPFMKLVSRTQVPDYYDIIKKPIALSTIREKVNNCEYQTAAEYIEDVELMFSNCLEYNPHNTNEAKAGLRLQAFFHSELQRLGLADR--------MTPPQKRPRM", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V9T4-1", "uniprot_id": "Q9V9T4_DROME", "id": "Q9V9T4-1", "name": "", "aln": "MPICKREGFDLNQKEGKNETFHDNDQVFCCYITKRIFRDYEHYFRHVMVINSTVWQCEATGKENLTYEEAVKSERAARKKMEQFKQSLRAPVLLVVEHAQQSAVNTLNMIVAKFLRKRYFIGEEVSVQAKK--NATYTVLGVKLDKNMPEPLNG-----------IYEDTDN-----------------------LVYRLRPNKGDPSAELDLPFRQLRRSRMEFNLENLSMFIKSNVSRVDGLLRPKPEAYKQYVTDPGVNFSTIFIGKMPRYSPAKIKKPDG-----------------------------------------------KKQSTLNKYIVAGEATAAKSKAKAKSDAKSLAEELERVKREKEAKLIELEKQKAEKKAQLIERVENECNLLLQKTDDLERTDQKVLPRYRQIVTLLPEHLLGDAFMMREFMHTYTGLLSGIEVFRQNLSF-YEMTRALTAREIAGPLSDILLVLLGTVFDLQKEEEEECAVTYLDRAAQT-----------QEPYWSMAQAAKSHLYAKRHFSFKVNELPLDALTLSEVLRLHLLGSGAFVNEKAERWRVMYRNGYSSKEDPGLELRLEHSHILRILKNHSVYQLKFKDIMLLIRCLMSQIMTYSGTINLIEERMEQTAKARQDLRALVVGENKRLAAVEINRKKLTQMHHLEVNGVEP-EKREALVEKLKKS-----------IAELHAQSDQQHRKHELQMLKLHSQLFNFLVYLGMDRCYR---------------KYYVLESMPGIFVEHSPDSLDTCLEQPITNKSQIEIRQQSALPKNRKDLRVYLLKLYGDD----EKKTKKKAKHSLENKENQEHRLNGSAEPMDVESDSPEAPTHFELLMCSGDKRSCIVHDSRNGQRQRWAYIYKAEEIDELIKALNPNGLREYELLQELSVLRSLIEQHAKTCPVDLLSLENETMRKKFMAAMESETNRKYGEANFGLPNGTDLNEVMRLHLVDRIIQFENDIYTGDLGRLKVKDMEKWRSDLLGGNYDAQCKLQWGPGGKLEDEAGSDNESHETHEEDDGALLGKYARKPYRDPGMYLAASADTKPLPDSDDEEDQHTNAVSIPIAVHNMASALLQVEQAIGKRFLKEPYG--------------------MKKWDPKQEALKLACDSRLHQWEVSLMESTSFAQVFLHLNILHDCIQWRRSTNKSLCKVCRRGSDPEKMLLCDECNAGTHMFCLKPKLRSVPPGNWYCNDCVKSLGLSNGQNEKDKKQATKKKRKFIVEEEDDEATDEEEEEKKDDDMTDEDAEHENE-KHDEDVEDDESVTSTPSSSRVNGRILRRPRTRPTSRRLTSKEIEEHAQEDVDSGDVSDDASLTAGEDTIEDESDEEKVCQKCFYDGGEIKCVQCRLFFHLECVHLKRPPRTDFVCKTCKPMPQRPRRRHSNMNGDHDRDEEEPKAKRPRNSLRLSIDKTARPSNGNNNNNNNNSSVNNNNHRRSGRRTNEHMPLNSAALYDLLEQIMKHKAAWPFLRPVLTSEVPDYHQIIKTPMDLAKIKSKLNMGAYQLNEELLSDIQLVFRNCDLYNVEGNEIYDAGCQLERFVIDRCRDMQLPFRPSDMNGEVKAC-------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**: ::: * :: .. :: :::** * *:.*** *:.:*.:.:: ** **.* .**: .***:**::**: *: .::.* :.* *:* :. :::* :: : : :::.*:* * *.: .. . :* * ** : .*:*: : *:::* . : : *: * : *. :.*.:::*.: . .* :: *..: * ** :* .. * : : : * * . : .. :.: * :.: * : ** . ::*:. :: .::: ** : .: : : : :*:* * * **. : * ** .::***:*: **:::: *:. : * :.::: : .*:.. : ***.::*:.:* ::*: **:** * : . .::.* **: ****:****:*.*** ::* :.*:.:.:*. :****.: ::: *. :**:* : : :::.: .:::* .* ::**: : *:*::* * . :::: * : : .:*. : : **:* * *. :. ::.:. :.: . :: : .. . . *: : :: * : :* .*. : : . *.. ::. * : . .. . . . : ::* : . ::::**.***..* ** * : * :. * . : ..:. .. ... . : :. :* * ::::*: ** * ** :** : . **: * .*.*: : . . . : : : : : :* : .. : .. . : . .** :* ** *:**.* ::*** * . . .: .:*. **: .:*::******. *. .: * :* :: **:**: .*.*:*:*** *. * * :*::***::** :*:* :* ::: .: :::: .. :*: :: : * . :: .. *.* * ::.*: . *. . : : . : : : : .. * : : . : . . . .. . :. : ... . . .. . . . . . . . . :* ***. . * * * ::::*. :***:: * :****::***.*: * *:.*:* *: * :.*::*:* ** ** .... .** :*: *. . : : * . ", "identical_positions": 263, "similar_positions": 467, "identity": "16.13%" }, { "cls_id": "homologset.agr.MGI:1309480", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q92541-1", "uniprot_id": "RTF1_HUMAN", "id": "Q92541-1", "name": "RNA polymerase-associated protein RTF1 homolog", "aln": "MRGRLCVGR-----AAAAAAAVAVPLAGGQEGSPGGGRRGSRGTTMVKKRKGRVVIDSDTEDSGSDENLDQELLSLAKRKRSDSEEKEPPVSQPAASSDSETSDSDDEWTFGSNKNKKKGKARKIEKKGTMKKQANKTASSGSSDKDSSAESSAPEEGEVSDSDS-----NSSSSSSDSDSSS--EDEEFHDGYGEDLMGDEEDRARLEQMTEKEREQELFNRIEKREVLKRRFEIKKKLKTAKKKEKKEKKKKQEEEQEKKK-----------------------------------------------------------LTQIQESQVTS--------HNKERRSKR------DEKLDKKSQAMEELKAERE---KRKNRTAELLAKKQ------------------PLKTSEVYSDDEEE---EEDDKSSEKSDRSSRTSSSDEEEEKEEIPPKSQPVSLPEELNRVRLSRHKLERWCHMPFFAKTVTGCFVRIGIGNHN--SKPVYRVAEITGVVETAKVYQLGGTRTNKGLQLRHGNDQRVFRLEFVSNQEFTESEFMKWKEAMFSAGMQLPTLDEINKKELSIKEALNYKFNDQDIEEIVKEKERFRKAPP--NYAMKKTQLLKEKAMAEDLGDQDKAKQIQDQLNELEERAEALDRQRTKN---ISAISYINQRNREWNIVESEKALVAESHNMKNQQM--DPFTRRQCKPTIVSNSRDPAVQAAILAQLNAKYGSGVLPDAPKEMSKGQGKDKDLNSKSASDLSEDLFKVHDFDVKIDLQVPSSESKALAITSKAPPAKDGAPRRSLNLEDYKKRRGLI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2AQ19-1", "uniprot_id": "RTF1_MOUSE", "id": "A2AQ19-1", "name": "RNA polymerase-associated protein RTF1 homolog", "aln": "MRGRLCVGRAAAVAAAVAAAAVAVPLAGGQEGSQGGVRRGSRGTTMVKKRKGRVVIDSDTEDSGSDENLDQELLSLAKRKRSDSEEKEPPVSQPAASSDSETSDSDDEWTFGSNKNKKKGKTRKVEKKGAMKKQANKAASSGSSDRDSSAESSAPEEGEVSDSES-----SSSSSSSDSDSSS--EDEEFHDGYGEDLMGDEEDRARLEQMTEKEREQELFNRIEKREVLKRRFEIKKKLKTAKKKEKKEKKKKQEEEQEKKK-----------------------------------------------------------LTQIQESQVTS--------HNKERRSKR------DEKLDKKSQAMEELKAERE---KRKNRTAELLAKKQ------------------PLKTSEVYSDDEEE---EDDDKSSEKSDRSSRTSSSDEEEEKEEIPPKSQPVSLPEELNRVRLSRHKLERWCHMPFFAKTVTGCFVRIGIGNHN--SKPVYRVAEITGVVETAKVYQLGGTRTNKGLQLRHGNDQRVFRLEFVSNQEFTESEFMKWKEAMFSAGMQLPTLDEINKKELSIKEALNYKFNDQDIEEIVKEKERFRKAPP--NYAMKKTQLLKEKAMAEDLGDQDKAKQIQDQLNELEERAEALDRQRTKN---ISAISYINQRNREWNIVESEKALVAESHNMRNQQM--DPFTRRQCKPTIVSNSRDPAVQAAILAQLNAKYGSGVLPDAPKEMSKGQGKDKDLNSKTASDLSEDLFKVHDFDVKIDLQVPSSESKALAITSKAPPAKDGAPRRSLNLEDYKKRRGLI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AGX2-1", "uniprot_id": "A0A8I6AGX2_RAT", "id": "A0A8I6AGX2-1", "name": "RNA polymerase-associated protein RTF1 homolog", "aln": "MRGRLCVGR-AAAVAAAVVAAVAVPLAGGQEGSPDGVRRGSRGTTMVKKRKGRVVIDSDTEDSGSDENLDQELLSLAKRKRSDSEEKEPPVSQPAASSDSETSDSDDEWTFGSNKNKKKGKARKVEKKGAMKKQANKAASSGSSDRDSSAESSAPEEGEVSDSDS-----NSSSSSSDSDSSSS-EDEEFHDGYGEDLMGDEEDRARLEQMTEKEREQELFNRIEKREVLKRRFEIKKKLKTAKKKEKKEKKKKQEEEQEKKK-----------------------------------------------------------LTQIQESQVTS--------HNKERRSKR------DEKLDKKSQAMEELKAERE---KRKNRTAELLAKKQ------------------PLKTSEVYSDDEEE---EDDDKSSEKSDRSSRTSSSDEEEEKEEIPPKSQPVSLPEELNRVRLSRHKLERWCHMPFFAKTVTGCFVRIGIGNHN--SKPVYRVAEITGVVETAKVYQLGGTRTNKGLQLRHGNDQRVFRLEFVSNQEFTESEFMKWKEAMFSAGMQLPTLDEINKKEFSIKEALNYKFNDQDIEEIVKEKERFRKAPP--NYAMKKTQLLKEKAMAEDLGDQDKAKQIQDQLNELEERAEALDRQRTKN---ISAISYINQRNREWNIVESEKALVAESHNMRNQQM--DPFTRRQCKPTIVSNSRDPAVQAAILAQLNAKYGSGALPDAPKEVSKGQGKDKDLNSKSASDLSEDLFKVHDFDVKIDLQVPSSESKALAITSKAPPAKDGAPRRSLNLEDYKKRRGLI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9W261-1", "uniprot_id": "RTF1_DROME", "id": "Q9W261-1", "name": "RNA polymerase-associated protein Rtf1", "aln": "------MGK--------RRTQSLIDSNSSDSDSESETNLESDLMSLAKKRKKPQTAAKSSSRSDSDS-------DWANNKAGAPSSKKKKRQKPSRDSSSSESNWDD------DSQDERQPARQSP---AQTQQEHKPPEQAS----QPAQLSEQEEGEVSDSDSDKSKSNSSSSGSDSSSSSSSSDSEFDDGFDDDLMGDDEDRRRLNGLSEKERETEIYKRIEQREIMRTRWEIERKLKLARRGEKNQEKSKNKGERAKKKKEKREKKARKAREAQAPLPTQASTSTLLDVEPKPSNEVRSASPLSTPALNRDAASTSAAVASIMPDDAASSAGVSDYFDHKERSKERKKNVEANKTDDKRSNAMALLKAKREGKAKREEEEAKRMAEKDRDDDKEELDSVSGCKSAVKLKASEIYSDDSGSSDWDEEEKPAGKRSRSNSSKASSESEDEEKAPQRPVFITTREDLNKLRLSRYKMERFVNLPIFESTVLNCFVRISIGNNG--QKPVYRVAEIVGVVETGKIYSLGTTRTNRGLRLKHGTQERVFRLEFISNQEFTENEFNKWNEVCQQSHVQMPTIDLIAIKQNDIKKALNYEFKDEDVDKIVEEKNRFRNRPT--NYAMKKTCLMKERDAAMLRGDYDIAQDLGQQIDELENRASELDKRRSHT---LNLISYINDRNRKKNVEDAEKAILEEARANKGLKIS-DPFTRRITQPRMGFKGAKKDEDDMQLAPLP--------PPPPGKKRPNEAGTSSASVRSTDSKDYSLYSLHDFDIDLDVPLPVNTN---SVPKPASKPAETVSKRSLNLEDYKKKRGLI", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53064-1", "uniprot_id": "RTF1_YEAST", "id": "P53064-1", "name": "RNA polymerase-associated protein RTF1", "aln": "---------------MSDLDEDLLALAGADESEEEDQVLTTTSAKRAKNNDQSLSKKRR------------------------------------------------------------------------------------------IEVGSVEDDDEEDDYN-------PYSVGNADYGSE-EEEEANPFPLEGKYKDESDREHLESLPEMERETLLFERSQ----IMQKYQERKLFRARGRDMKEQQQRAKNDEDSRKT-----------------------------------------------------------RASTRSTHATG-------------------------HSDIKASKLSQLKKQRARKNRHYSDNEDEDDEED-------------------YREEDYKDDEGSEYGDDEEYNPFDRRDTYDKREEVEWAEEEDEQDREPE----ISDFNKLRIGRSFVAKFCFYPGFEDAVKGCYGRVNVGTDKRTGKTSYRMVRIERVFLQ-KPYNMGKFYTNQYFGVTQGKDRKVFQMNYFSDGLFAEDEYQRYLRALDNSQMIKPSLHSLSNKTKEVMDFVNTPLTDKTTDEVVRHRMQFNKKLSGTNAVLEKTVLREKLQYAKETNNEKDIAKYSAQLRNFEKRMSVYEKHHENDQSDIKKLGELTSKNRKLNMSNIRNAEHVKKEDSNNFDSKSDPFSRLKTRTKVYYQEIQKEENAKAKEIAQQ-------EKLQEDKDAKDKREKELLVAQFRRLGGLERMVGELDIKFDLKF--------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ..:... : . .*:.. : . *:.: .*. . . * .::. .* .:.* . :. *:.** :*: :.* *** :::* : : ::: .: :: : *:::: :: * :*. :. ..:. * ::. : ** :* :: . . ::: : .: .*: . ::: :. : . . . . *:::: .. .::*::*:.* : :: * * .:* .*: *:.:*.. *. **:..* *. * *.:* **: : : :*.:.:**::::.*: *:*.*: :: .. .: : *::. : * .: . :* :.*: :::*..: :*.: . * .::** * :: * .: . . *: ::*:* . :::: : :. :. :..:**: *: : .:* : . .. . ***:* :. : : . : . : .. . : ::*:.:*: . ", "identical_positions": 74, "similar_positions": 228, "identity": "8.94%" }, { "cls_id": "homologset.agr.MGI:1309481", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G5E870-1", "uniprot_id": "TRIPC_MOUSE", "id": "G5E870-1", "name": "E3 ubiquitin-protein ligase TRIP12", "aln": "MSNRPNNNPGGSLRRSQRNTAGAQPQDDSIGGR------------------------------------------SCSSSSAVIVPQPEDPDRANTSERQKTGQVPKKDNSRGVKRSASPDYNR--TNSPSS-----------------AKKPRAFQHIESFSETNKPHS-----------KSKKRHLDQ-------------------------------------EQQLKSAQLPSTSKAHTRKSV------AAGSSRNQKRKRTESSC-------------------------------------------------------VKSGSGS---ESTGAE---------ERSAKPIKLASKSATSAKAGCSTITDSSS----------------------------------------------------------------------------------------------------------------------------------------------AASTSSSSSAIASASST-----VPAGARVKQGKDQNKARRSRSASSPS-------------------------PRRSSREKEQSKTGGSSKFDWAARFSPKVSLPKTKLSLPGSSKSETS------------------------------------------KPGPSGLQAKLASLRKSTKKRSESPPAELP--------------------------------------------SLRRSTRQKT----TGSCASTSRRGSGLGKRGAAEARRQEKMADPE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------SNQETVNSSAARTDEAPQGAAASSSVAGAVG------------MTTSG-------------ESESDDSEMGRLQALLEARGLPPHLFGPLGPRMSQLFHRTIGSGASSKAQQLLQGLQAS-DESQQLQAVIEMCQLLVMGNEETLGGFPVKSVVPALITLLQMEHNFDIMNHACRALTYMMEALPRSSAVVVDA--IPVFLEKLQVIQCIDVAEQALTALEMLSRRHSKAILQAGGLADCLLYLEFFSINAQRNALAIAANCCQSITPDEFHFVADSLPLLTQRLTHQDKKSVESTCLCFARLVDNFQHEENLLQQVASKDLLTNVQQLLVVTPPILSSGMFIMVVRMFSLMCSNCPTLAVQLMKQNIAETLHFLLCG--ASNGSCQEQIDLVPRSPQELYELTSLICELMPCLPKEGIFAVDTMLKKGNAQNTDGAIWQWRDDRGLWHPYNRIDSRIIEAAHQVGEDEISLSTLGRVYTIDFNSMQQINEDTGTARAIQRKPNP--------------------------------LANSNTSG------------YSELKKD---DARAQLMKEDPELAKSFIKTLFGVLYEVYSSSAGPAVRHKCLRAILRIIYFAD-----------AELLKDVLKNHAVSSHIASMLSSQDLKIVVGALQMAEILMQKLPDIFSVYFRREGVMHQVKHLAE---------SESLLTSPPKACTNGSGS----------------LGSTTPASSGTATAATNASADLGSPSLQHSR-----------DDSLDLSP---------------------------------------------------------------------------------------------------------QGRLSDVLKRKRLPKRGPRRPKYSPPRDDDKVDNQAKS---------------------------------------------------PTTTQSPKSSFLASLNPKTWGRLSAQSNSNNIEPAR---------------------------------TAGVSGLARAASKDTISN-----------NREKIKGWIKEQAHKFVERYFSSEN------------MDGSN---------------PALNVLQRLCAATEQLNLQVDGGAECLVEIRSIVSESDVSSFEIQHSGFVKQLLLYLTSKNEKDAVGREIRLKRFLHVFFSSPLP-GEEPVGRVEPVGHAPLLALVHKMNNCLSQMEQFPVKVHDFPSGNGAGGSFSLNRGSQALKFFNTHQLKCQLQRHPDCANV-KQWKGGPVKIDPLALVQAIERYLVVRGYGRVREDDEDSDDDGSDEEIDESLAAQFLNSGNVRHRLQFYIGEHLLPYNMTVYQAVRQFSVQAEDERESTDDESNPLGRAGIWTKTHTIWYKPVREDEES--------------------------------------TKDCVGGKRGRAQTAPTKTSPRNAKKHDELWHDGVCPSVANPLEVYLIPT-PPENITFEDPSLDVILLLRVLHAISRYWYYLYDNAMCKEIIPTSEFINSKLTAKANRQLQDPLVIMTGNIPTWLTELGKTCPFFFPFDTRQMLFYVTAFDRDRAMQRLLDTNP-EINQSDSQDSRVAPRLDRKKRTVNREELLKQAESVMQDLGSSRAMLEIQYENEVGTGLGPTLEFYALVSQELQRADLCLWRGEE---------------------------------------------------------------------------------------------------------------VTLSNPKGSQEG---------------------TKYIQNLQGLFALPFGRTAKPAHIAKVKMKFRFLGKLMAKAIMDFRLVDLPLGLPFYKWMLRQETSLTSHDLFDIDPVVARSVYHLEDIVRQKKRLEQDKSQTKESLQYALETLTMNGCSVEDLGLDFTLPGFPNIELKKGGKDIPVTIHNLEEYLRLVIFWALNEGVCRQFDSFRDGFESVFPLCHLQYFYPEELDQLLCGSKADT----WDAKTLMECCRPDHGYTHDSRAVKFLFEILSSFDNEQQRLFLQFVTGSPRLPVGGFRSLNPPLTIVRKTFESTENPDDFLPSVMTCVNYLKLPDYSSIDIMRDKLLIAAREGQQSFHLS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1LP64-1", "uniprot_id": "TRIPC_RAT", "id": "F1LP64-1", "name": "E3 ubiquitin-protein ligase TRIP12", "aln": "MSNRPNNNPGGSLRRSQRNTAGAQPQDDSIGGR------------------------------------------SCSSSSAVIVPQPEDPDRANTSERQKTGQVPKKDNSRGVKRSASPDYNR--TNSPSS-----------------AKKPRAFQHIESLSETNKPPS-----------KSKKRHLDQ-------------------------------------EQQLKSAQLPSTSKAHTRKSV------AAGSSRSQKRKRTESSC-------------------------------------------------------VKSGSGS---ESTGAE---------ERSAKPTKLASKSATSAKAGCSTITDSSS----------------------------------------------------------------------------------------------------------------------------------------------AASTSSSSSAVASASST-----VPAGARVKQGKDQNKARRSRSASSPS-------------------------PRRSSREKEQSKTGGSSKFDWAARFSPKVSLPKTKLSLPGSSKSETS------------------------------------------KPGPSGLQAKLASLRKSTKKRSESPPAELP--------------------------------------------SLRRSTRQKT----TGSCASTSRRGSGLGKRGAAEARRQEKMADPE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------GNQETVNSSAARTDEAPQGAAASSSVAGAVG------------MTTSG-------------ESESDDSEMGRLQALLEARGLPPHLFGPLGPRMSQLFHRTIGSGASSKAQQLLQGLQAS-DESQQLQAVIEMCQLLVMGNEETLGGFPVKSVVPALITLLQMEHNFDIMNHACRALTYMMEALPRSSAVVVDA--IPVFLEKLQVIQCIDVAEQALTALEMLSRRHSKAILQAGGLADCLLYLEFFSINAQRNALAIAANCCQSITPDEFHFVADSLPLLTQRLTHQDKKSVESTCLCFARLVDNFQHEENLLQQVASKDLLTNVQQLLVVTPPILSSGMFIMVVRMFSLMCSNCPTLAVQLMKQNIAETLHFLLCG--ASNGSCQEQIDLVPRSPQELYELTSLICELMPCLPKEGIFAVDTMLKKGNAQNTDGAIWQWRDDRGLWHPYNRIDSRIIEAAHQVGEDEISLSTLGRVYTIDFNSMQQINEDTGTARAIQRKPNP--------------------------------LANTNTSG------------YSDLKKD---DARAQLMKEDPELAKSFIKTLFGVLYEVYSSSAGPAVRHKCLRAILRIIYFAD-----------AELLKDVLKNHAVSSHIASMLSSQDLKIVVGALQMAEILMQKLPDIFSVYFRREGVMHQVKHLAE---------SESLLTSPPKACTNGSGS----------------LGSTTPASSGTATAATNASADLGSPSLQHSR-----------DDSLDLSP---------------------------------------------------------------------------------------------------------QGRLSDVLKRKRLPKRGPRRPKYSPPRDDDKVDNQAKS---------------------------------------------------PTTTQSPKSSFLASLNPKTWGRLSAQSNSNNIEPAR---------------------------------TAGVSGLARAASKDTISN-----------NREKIKGWIKEQAHKFVERYFSSEN------------MDGSN---------------PALNVLQRLCAATEQLNLQVDGGAECLVEIRSIVSESDVSSFEIQHSGFVKQLLLYLTSKSEKDAVSREIRLKRFLHVFFSSPLP-GEEPVGRVEPVGHAPLLALVHKMNNCLSQMEQFPVKVHDFPSGNGSGGSFSLNRGSQALKFFNTHQLKCQLQRHPDCANV-KQWKGGPVKIDPLALVQAIERYLVVRGYGRVREDDEDSDDDGSDEEIDESLAAQFLNSGNVRHRLQFYIGEHLLPYNMTVYQAVRQFSVQAEDERESTDDESNPLGRAGIWTKTHTIWYKPVREDEES--------------------------------------SKDCVGGKRGRAQTAPTKTSPRNAKKHDELWHDGVCPSVANPLEVYLIPT-PPENITFEDPSLDVILLLRVLHAISRYWYYLYDNAMCKEIIPTSEFINSKLTAKANRQLQDPLVIMTGNIPTWLTELGKTCPFFFPFDTRQMLFYVTAFDRDRAMQRLLDTNP-EINQSDSQDSRVAPRLDRKKRTVNREELLKQAESVMQDLGSSRAMLEIQYENEVGTGLGPTLEFYALVSQELQRADLGLWRGEE---------------------------------------------------------------------------------------------------------------VTLSNPKGSQEG---------------------TKYIQNLQGLFALPFGRTAKPAHIAKVKMKFRFLGKLMAKAIMDFRLVDLPLGLPFYKWMLRQETSLTSHDLFDIDPVVARSVYHLEDIVRQKKRLEQDKSQTKESLQYALETLTMNGCSVEDLGLDFTLPGFPNIELKKGGKDIPVTIHNLEEYLRLVIFWALNEGVCRQFDSFRDGFESVFPLSHLQYFYPEELDQLLCGSKADT----WDAKTLMECCRPDHGYTHDSRAVKFLFEILSSFDNEQQRLFLQFVTGSPRLPVGGFRSLNPPLTIVRKTFESTENPDDFLPSVMTCVNYLKLPDYSSIEIMRDKLLIAAREGQQSFHLS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q14669-1", "uniprot_id": "TRIPC_HUMAN", "id": "Q14669-1", "name": "E3 ubiquitin-protein ligase TRIP12", "aln": "MSNRPNNNPGGSLRRSQRNTAGAQPQDDSIGGRSHLGQAKHKGYSPPESRKSNSKAPKVQSNTTSELSRGHLSKRSCSSSSAVIVPQPEDPDRANTSERQKTGQVPKKDNSRGVKRSASPDYNR--TNSPSS-----------------AKKPKALQHTESPSETNKPHS-----------KSKKRHLDQ-------------------------------------EQQLKSAQSPSTSKAHTRKSG------ATGGSRSQKRKRTESSC-------------------------------------------------------VKSGSGS---ESTGAE---------ERSAKPTKLASKSATSAKAGCSTITDSSS----------------------------------------------------------------------------------------------------------------------------------------------AASTSSSSSAVASASST-----VPPGARVKQGKDQNKARRSRSASSPS-------------------------PRRSSREKEQSKTGGSSKFDWAARFSPKVSLPKTKLSLPGSSKSETS------------------------------------------KPGPSGLQAKLASLRKSTKKRSESPPAELP--------------------------------------------SLRRSTRQKT----TGSCASTSRRGSGLGKRGAAEARRQEKMADPE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------SNQEAVNSSAARTDEAPQGAAASSSVAGAVG------------MTTSG-------------ESESDDSEMGRLQALLEARGLPPHLFGPLGPRMSQLFHRTIGSGASSKAQQLLQGLQAS-DESQQLQAVIEMCQLLVMGNEETLGGFPVKSVVPALITLLQMEHNFDIMNHACRALTYMMEALPRSSAVVVDA--IPVFLEKLQVIQCIDVAEQALTALEMLSRRHSKAILQAGGLADCLLYLEFFSINAQRNALAIAANCCQSITPDEFHFVADSLPLLTQRLTHQDKKSVESTCLCFARLVDNFQHEENLLQQVASKDLLTNVQQLLVVTPPILSSGMFIMVVRMFSLMCSNCPTLAVQLMKQNIAETLHFLLCG--ASNGSCQEQIDLVPRSPQELYELTSLICELMPCLPKEGIFAVDTMLKKGNAQNTDGAIWQWRDDRGLWHPYNRIDSRIIEAAHQVGEDEISLSTLGRVYTIDFNSMQQINEDTGTARAIQRKPNP--------------------------------LANSNTSG------------YSESKKD---DARAQLMKEDPELAKSFIKTLFGVLYEVYSSSAGPAVRHKCLRAILRIIYFAD-----------AELLKDVLKNHAVSSHIASMLSSQDLKIVVGALQMAEILMQKLPDIFSVYFRREGVMHQVKHLAE---------SESLLTSPPKACTNGSGS----------------MGSTTSVSSGTATAATHAAADLGSPSLQHSR-----------DDSLDLSP---------------------------------------------------------------------------------------------------------QGRLSDVLKRKRLPKRGPRRPKYSPPRDDDKVDNQAKS---------------------------------------------------PTTTQSPKSSFLASLNPKTWGRLSTQSNSNNIEPAR---------------------------------TAGGSGLARAASKDTISN-----------NREKIKGWIKEQAHKFVERYFSSEN------------MDGSN---------------PALNVLQRLCAATEQLNLQVDGGAECLVEIRSIVSESDVSSFEIQHSGFVKQLLLYLTSKSEKDAVSREIRLKRFLHVFFSSPLP-GEEPIGRVEPVGNAPLLALVHKMNNCLSQMEQFPVKVHDFPSGNGTGGSFSLNRGSQALKFFNTHQLKCQLQRHPDCANV-KQWKGGPVKIDPLALVQAIERYLVVRGYGRVREDDEDSDDDGSDEEIDESLAAQFLNSGNVRHRLQFYIGEHLLPYNMTVYQAVRQFSIQAEDERESTDDESNPLGRAGIWTKTHTIWYKPVREDEES--------------------------------------NKDCVGGKRGRAQTAPTKTSPRNAKKHDELWHDGVCPSVSNPLEVYLIPT-PPENITFEDPSLDVILLLRVLHAISRYWYYLYDNAMCKEIIPTSEFINSKLTAKANRQLQDPLVIMTGNIPTWLTELGKTCPFFFPFDTRQMLFYVTAFDRDRAMQRLLDTNP-EINQSDSQDSRVAPRLDRKKRTVNREELLKQAESVMQDLGSSRAMLEIQYENEVGTGLGPTLEFYALVSQELQRADLGLWRGEE---------------------------------------------------------------------------------------------------------------VTLSNPKGSQEG---------------------TKYIQNLQGLFALPFGRTAKPAHIAKVKMKFRFLGKLMAKAIMDFRLVDLPLGLPFYKWMLRQETSLTSHDLFDIDPVVARSVYHLEDIVRQKKRLEQDKSQTKESLQYALETLTMNGCSVEDLGLDFTLPGFPNIELKKGGKDIPVTIHNLEEYLRLVIFWALNEGVSRQFDSFRDGFESVFPLSHLQYFYPEELDQLLCGSKADT----WDAKTLMECCRPDHGYTHDSRAVKFLFEILSSFDNEQQRLFLQFVTGSPRLPVGGFRSLNPPLTIVRKTFESTENPDDFLPSVMTCVNYLKLPDYSSIEIMREKLLIAAREGQQSFHLS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1RCR6-1", "uniprot_id": "TRIPC_DANRE", "id": "F1RCR6-1", "name": "E3 ubiquitin-protein ligase TRIP12", "aln": "MSNRPNSNPGGSLRRSQRNTAAAQPIDHTLAGRN-----------------------------------------SLSLSVGSLSIPDPDLEAAGTSGQQGR---REGSSTRALKRSSVSEPNI--TFSPSP-----------------AKRPKVVSSHFSDSSASGPSAPAISPEVTEPRKAPASVSTK-------------------------------------SKKRRLAAEPAPARALSKKSSSYPGPSGASSTPSQKRKKADATL-------------------------------------------------------LSSSSSSSLPSSSSAAGPLPPRSEASRAAKPTKLASKSAASAKAGCSTVTDSSS----------------------------------------------------------------------------------------------------------------------------------------------SSASSSSSSSSSSSAATGTNSCAPQGARLKQGKDQSKARRSRSASSPS-------------------------PRRSSRDKEQSKAAGSSKFDWASRFNSKVNLPKPKLSLPGSAKAETSS-----------------------------------------KPGPSGLQAKLASLRKSTKKRSESPPAELP--------------------------------------------SCRRSTRQKT----TGSCASTSRRGSGLGKRGAAEARRQEKMADSD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------NNQDGANSSAARTEETPQGASASSSVAGAVG------------MTTSG-------------ESESDDSEMGRLQALLEARGLPPHLFGPFGPRMSQLFHRTIGSGASSKAQQLLQGLQATGDESQQLQAAIEMCQLLVMGNEETLGGFPVKSVVPALITLLQMEHNFDIMNHASRALTYMMEALPRSSAVVVDA--IPVFLEKLQVIQFIDVAEQALTALEMLSRRHSKAILQAGGLADCLLYLEFFSINAQRNALAIAANCCQSITPDEFHFVADSLPLLTQRLTHQDKKSVESTCLCFARLVDNFQHEENLLQQVASRDLLTNIQQLLVLTPPVLSSGMFIMVVRMFSLMCSNCPCLAVQLMKQNIAETLRFLLCG--ASNGSCQEQIDLVPRSPQELYELTSLICELMPCLPREGIFAVDAMLKKGSAQTTEGAIWQWRDDRGLWHPYNRIDSRIIE---------------------------QINEDTGTARAIQRKPNP--------------------------------LANPNTGG------------HLEVRRE---DARAQLMKEDPELAKCFIKTLFGVLYEVYSSSAGPAVRHKCLRAILRIIYFAD-----------AELLKDVLRNHAVSSHIASMLSSQDLKIVVGSLQMAEILMQKLPDVFSVYFRREGVMHQVKNLAE---------SEVFLTSPPKACTSGTAS----------------LCTTT-ITTATTTAASNVTPDLGSPSFQHSM-----------DDSLDLSP---------------------------------------------------------------------------------------------------------QGRLSDVLKRKRLPKRGPRRPKYSPPRDDDKVDNQAKS---------------------------------------------------PTTTQSPKSSFLASLNPKTWGKLGTQANSANSEPSR---------------------------------TAGVSGLARVPPKDSVSN-----------NRDKIKAWIKEQASKFVERYFNSES------------VDGSN---------------PALNVLQRLCTATEQLNLQMDSGVECLEEISSIVSESDVSSFEIQHSGLVKQLLLYLTSNSERDTISRDERIKRFLHVFFGCPIP-GQEPPGRLDPTENGPLLALVHKMNNCLSQMEQFPVKVHDFPSGNGNG-----SRGSQALKFFNTHQLKCQLQRHPDCTNV-KQWKGGPVKIDPLALVQAIERYLVVRGYGRIREEDEDSDDDGSDDEIDESLAAQFLNSGSVRHRLQFYIGEHLLPYNMTVYQAVRQFSLQAEEERESTDDEANPLGRAGIWTKTHTVWYKPVREDEEG--------------------------------------CKDAVGGKRGRAQTAPTKTSPRNAKKQDELWHEGVCPSVANPLETYLICD-PPEGITFDDPSMEVILLLRVLHSISRYWFYLYDNAACKEIIPTGEFINSKLTAKANRQLQDPLVIMTGNIPTWLTELGKTCPFFFPFDTRQMLFYVTAFDRDRAMQRLLDTNP-EINQSDSQDSRVAPRLDRKKRTINRDELLKQAESVMQDLGSSRAMLEIQYENEVGTGLGPTQEFYALVSQELQRADLGLWRGEE---------------------------------------------------------------------------------------------------------------VTLSNPKGSQEG---------------------TKYMFSSRGLFAVPFGRTTKPAHIAKIKMKFRFLGKLMAKAIMDFRLLDLPLGLPFYKWMLRHESSISSHDLVNIDPGVAKSIQHLEDIIRQKKRIEQDRSHTRETLQQALESLNMNGCSVEDLGLDFTLPGFPNIELKKGGKDVPVTIHNLEDYLRLVVYWTLNEGVLRQFESFREGFESVFPLHHLQYFYPEELDQLLCGSKSES----WDVKTLMECCRPDHGYTHDSRAVRFLFEVLSSFDAEQQRLFLQFVTGSPRLPVGGFRSLNPPLTIVRKTFESTENPDDFLPSVMTCVNYLKLPDYSSIEIMREKLLIAAREGQQSFHLS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VN58-1", "uniprot_id": "Q9VN58_DROME", "id": "Q9VN58-1", "name": "E3 ubiquitin-protein ligase", "aln": "MAESVKSQSLSALTEGQHDDGGSTATSATLANKTSGTNTTSASNHSSQRRRNNNTNSNRNKSHHKNEKRNAPATSGPAVSSSVDVVPATSTASATSTRRSRSQGRHSSAAALSSKESQIPKRSVGAIRSPSSPAFNSIPVVSDQSLSPGSRKRQLNQHNNSNNKASSSHQSAPGGDQLVCAPLKKRRLQQSLGSGICEGAVEINLGAASFDHTPRQASGDCVAQRTRSKTISPEELPSTSSAAAARHHQIRPSASSTSFSSSHRNKRKASIGGSIAAVETTPHRGTAAARAGRSGNLLNYYRKTRKVSHTRSSQKSEKQSIPAEDTTANRNGSAGSGSSSKSGVIPKNRKSLRHSQQNLLDTEAAEVESAAAETGGEQQSEHGNLDVIDQLPTPEAGPNQSEASGIHNQSQLEADRQPVVQDEDDEEDDEEEEEEEEEEVGFYGIVNSAGSSYEEDTQIVAEEDEITTEEEVDDEDDDEIEEEDLSESEFAQQLIGELGGERQQPQRATNNAKKTKNNTPAVAAASTIKATTTATTSSGYQQRAAPHGQGAAPGAGGGGPRATRSSNSNSSNNVVDYSIMPHLTTVATTTPHALTPQQHQQQRQPPQPPSHQQQQVHQQQQPPQLLPTHQFAHLSSFVTPTAAAAAAAAAAHYPPASAAAAYFAQQQHHQHQHQHQQQHVQQAQAPQPHYYHSSVAVLHQPPPHHFTSTGAGPPPALFQQQAPPQLTRYTPATATTAATFVPPQQQQVVYNPQQQQHSSLRRSSRGKTGSCVSSAAAAQQQQHHQQQQHSSAAAAVQQQLLPPPGTYQYQQVGGNTVVVAVRHQQQLQQQQQQQQQLALHHQHQQQQHQQQQQQHQQQQHQQQQRATLVQPGFLFSYRSNQPQQQQQPAQQIHQGPKVTHSSAASDALTYSLMAQQPPSGPPHAGGQQITPGANSANLSIVAAALSAARDVGGGSDGGGSAGGATPATGASASSVGNTSAVGASSSSNSSAGQAASSNSNNVTATGSGSAPGGGPTSTGTTSGTQHGSGSGAAAAVDSESDDSEVGRLQALLEARGLPPHLFGALGPRVTHILHRTIGNSSSSKANQLLQGLQSH-DESQQLQAAIEMCQMLVMGNEDTLAGFPIKQVVPALIQLLRMEHNFDIMNNACRALAYMLEALPRSSGTVVEA--VPVFLEKLQVIQCMDVAEQSLSALEILSRRHNKAILQANGISACLTYLDFFSIVAQRAALAIAANCCLNMHPEEFHFVAESLPLLARLLSQQDKKCIESVCSAFCRLVESFQHDGQRLQQIASPDLLKNCQQLLLVTPAILNTGTFTAVVRMLSLMCCSCPDLAISLLRNDIAATLLYLLTGNAEPAAASATHVELISRSPSELYELTCLIGELMPRLPLDGIFAVDSLLDRPTLNTQDQVHWQWRDDRGSWHNYSTIDSRLIEAANQSSEDEISLSTFGRTYTVDFHAMQQINEDTGTTRPVQRRLNHNYVAPMSAGQDLTTTSAGSAAAGGASTSAAAAAASSNNNNNNNNNPPGNSVNLNQVKRRPSLDARIACLKEERGLAADFIKHIFNVLYEVYSSSAGPNVRYKCLRALLRMVYYAT-----------PELLRQVLKYQLVSSHIAGMLGSNDLRIVVGALQMAEILMRQLPDVFGTHFRREGVIYQFTQLTDPNNPICANPSPKPLSATATPTANAGGSQSAPASANSLQVNPFFMDSAPGLSSASTTPSSSKHQSYSVKSFSHAMNALTASAKGTPSGALDATSSSTTAGGYNYSSSAPSSSSGAPAAYFVTQQGDPRQYVHFQQPAVPAPPPQQELLPSGVQQQGQQVPQVIYQPHHQQPAHLVLASTSSGAASSSSSSSSSSSASALQHKMTDMLKRKAPPKRKSQSGGRAKSRQEDAAVAPAGSGPGGAPPSSSGSAMHELLSRATSLGSGNGGRSTPNSGGGSGSSKSRFNAGNSSNAGSSKSSFLASLNPARWGRQTHQNHHHHHQQSQQQHHGLSKDSGNSNSTGSGSGAGLAYTVSQHGAGSGAGGLNAAAVAASISKSISHANLLAAANRERARQWVREQAVDFVKRYTEQEAKRSKAASESGATQSGSSGVGLSSTGNTPLSTAGSTNVLERLSSILFKLNGSYHDCLDALLELKTILLESDISPFEVNHSGLIKAMLNYMTS--ETGLVERDARLRSFMHVFAGLPLEPLLQNVGQMPTIEPIAFGAFVAKLNGCVTQLEQFPVKVHDFPAGPGGR------SNQSALRFFNTHQLKCNLQRHPQCNNL-RQWKGGTVKIDPLAMVQAIERYLVVRGYGGIRAD----SDDDSEEDMDDNVAAVVLSQASFRHKLQFTIGDHVLPYNMTVYQAVKQFSPLVSEQPETDNESETLLGNASIWVQQHTIHYRPVEEEVTSGAAAGAASSSSSCSSGVQKQQSSSSSASSCVNATSSCSSSSGVASGGGSLTKKAHKSSSKFMRKKTELWHEGIAPVVISALKPFLSSSLPADVVTVQDASLDALCMLRVIHALNRHWDHLYGCVVRQNIIPQSDFIHPKIMAKANRQLQDPLVIMTGNLPQWLPQIGMACPFLFPFETRHLLFYATSFDRDRALQRLLDTTP-DLNAAESSE-RVAPRLDRRKRAISRTEILKQAEHILQDFGHSKALLEIQYENEVGTGLGPTLEFYALVSAELQRTDLGLWNGSDSYKQNSVTIVDVVKANSAVLHIEDALEATTTDQNTPAVAGASLVSSSTTTTTTTAQQHQHPPTRSSSRSHVLRSGAGQQPVEHSSSSAGANENALNMVIAQQFSDTNSANPAAIDNPSSTTTATTVVQHNTTTNNSSIITTTTTTSYVHAVHGLFPLPLGKSSKLPQMTKAKAKFKFLGKFMAKAVMDSRMLDLPFSLPFYRWLVSEEHSIGLADLMRVAPEVQNTLVRLQDLVRQREYILSDPNIDAMEKTEKIEQLDLDGCPIADLGLDFVLPGHANIELCRGGRDTPVTVHNLHQYISLVTYWFLIEGVQKQFEALREGFDSVFPIQRLRMFYPEELECVFCGSGSEQQHSRWEIKMLQESCRTDHGFHQDSQAIQYLYEILASYNRDEQRAFLQFVTGSPRLPTGGFKALTPPLTIVRKTLDENQNPNDYLPSVMTCVNYLKLPDYSSREVMRQKLKVAANEGSMSFHLS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P33202-1", "uniprot_id": "UFD4_YEAST", "id": "P33202-1", "name": "Ubiquitin fusion degradation protein 4", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSENNSHNLDEHESHS--ENS--------------------------DYMMDTQVEDDYDEDGHVQGEYSYYPDEDEDEHMLSSVGSFEADDG------------------------------------------EDDDNDYHHEDDSGLLYGYHRTQN-----------------------------------------------------------------GSDEDRNEEEDGLERSHDNNEFGSNPLHLPD--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ILETFAQRLEQRRQTSEGLG-------------------------------QHPVGRTLPEILSMIGGRMERSAESSARNERISKLIENTG-----NASEDPYIAMESLKELSENILMMNQMVVDRIIPMETLIG------NIAAILSDKILREELELQMQACRCMYNLFEVCPESISIAVDEHVIPILQGKLVEISYIDLAEQVLETVEYISRVHGRDILKTGQLSIYVQFFDFLTIHAQRKAIAIVSNACSSIRTDDFKTIVEVLPTLKPIFSNATDQPILTRLVNAMYGICGALHGVDKFETLFSLDLIERIVQLVSIQDTPLEN--KLKCLDILTVLAMSSDVLSRELREKTDIVDMATRSFQHYSKSPNAGLHETLIYVPNSLLISISRFIVVLFPPED-ERILSADKYTGN--------------SDRGVISNQEKFDS-------------------------------------------------------------------------------------------------------------------------------LVQCLIPILVEIYTNAADFDVRRYVLIALLRVVSCINNSTAKAINDQLIKLIGSILAQKETASNANGTYSSEAGTLLVGGLSLLDLICKKFSELFFPSIKREGIFDLVKDLSV---------------------------------------------------------------DFNNIDLKEDG-----------NENISLSD-----------------------------------------------------------------------------------------------------------------------EEGDLHSSIEECDEGDEEYDYEFT----------------------------------------------------------DMEIPDSVKPKKISIHIFRTLSLAYIKNK-----------------------------------GVNLVNRVLSQMNVEQ-----------------EAITEELHQIEGVVSILEN------------------------------------------PSTPDKTEEDWKGIWSVLKKCIFHEDFDVSGFEFTSTGLASSITKRITS----STVSHFILAKSFLEVFEDCIDR-------------------FLEILQSALTRLENFSIVDCGLHDGGGVS------------SLAKEIKIKLVYDGDASKDNIGTDLSSTIVSVHCIASFTSLNEFLRHRMVRMRFLNSLIPNLTSSSTEADREEEENCLDHMRKKN-FDFFYDNEKVDMESTVFGVIFNTFVRRNRDLKT------------LWDDTHTIKFCKSLE---------------------------------------------------GNNRESEAAEEANEGKKLRDFYKKREFAQVD------------------TGSSADILTLLDFLHSCG---------------VKSDSFINSKLSAKLARQLDEPLVVASGALPDWSLFLTRRFPFLFPFDTRMLFLQCTSFGYGRLIQLWKNKSKGSKDLRNDEALQQLGRITRRKLRISRKTIFATGLKILSKYGSSPDVLEIEYQEEAGTGLGPTLEFYSVVSKYFARKSLNMWRCNS-----------------------------------------------------------------------------------------------------------------YSYRSEMDVD---------------------TTDDYITTLLFPEPLN---PFSNNEKVIELFGYLGTFVARSLLDNRILDFRFSKVFFELLHRMSTPNVTTVPSDVETCLLMIELVDPLLAKSLKYIVANKD---------------DNMTLESLSLTFTVPGNDDIELIPGGCNKSLNSSNVEEYIHGVIDQILGKGIEKQLKAFIEGFSKVFSYERMLILFPDELVDIFG-RVEED----WSMATLYTNLNAEHGYTMDSSIIHDFISIISAFGKHERRLFLQFLTGSPKLPIGGFKSLNPKFTVVLKHAEDGLTADEYLPSVMTCANYLKLPKYTSKDIMRSRLCQAIEEGAGAFLLS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : ::* . * : . : : . :: .* : . : . :: . .: ... : .: : . . * . . * ... . : .: ::: .* . .. . *:::::..* . ::: .::: : *::: :* :: * :. :.*:: :..:::: :*.*.: ::*. *.* . .*: :*:: ** *. :*:*** * ::* :** *.: **::. :: : :::*::* *** *:**.:*.* .: .::*: :.: ** * ::: .: : : : . * : :: : * **: . **: : . *.. : :::::. .. *: .* .: : . : *: . . * .:: :* *:* : *::.* . .*** . :** ::: :: :* *:*:.:*. ** * *:**:: :*: .:* : .:*: . .*: ::**.*.: ::: :::.::* ::***:: ...*: . . .:.. . :. : :. : * : . .: *::* . : : * . : . .:.: : *: .: * . . . . .: : : : *:* **. :*: . : :** . : : : *:.** . :: ::..::::*:*.: .: * * : : ::* : ... *: : .. *.:. :* . :::.:* * : . .*. : * . *. :: ::* .:. : : **: .: : . : :: :* . **: : * * ... :* ::::. . * ..* : : :* .:*: . : ..**:.*: ** ***::***: :* :* * : **:***:** ::: *:*. .* :* :.. . : :.. : *: *:* :.* :: . ::.. * * :***:*::*.******* ***::** : * .* :*. .. . . *. **. *:. .: * * :**.::*::::* *::*: :. *:. : . . : . : : :. : : : . :. .: .*.* *.:** :*** ** : .:. *:.:*: * * :*: :*:.:: :**..**. :: ::*:** :: : *. * ..:**: ** :: : .:::::. .::* ****:****:** ***::*.* :*:* * :. ..:::*******.******.*:* ::**.:* * .** :* **", "identical_positions": 268, "similar_positions": 535, "identity": "8.46%" }, { "cls_id": "homologset.agr.MGI:1309489", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62915-1", "uniprot_id": "CSKP_RAT", "id": "Q62915-1", "name": "Peripheral plasma membrane protein CASK", "aln": "MADDDVLFEDVYELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTEDLKREASICHMLKHPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILEALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLG--ESGLVAGGRVGTPHFMAPEVVKREPYGKPVDVWGCGVILFILLSGCLPFYGTKERLFEGIIKGKYKMNPRQWSHISESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYAYKIHLPETVEQLRKFNARRKLKGAVLAAVSSHKFNSFYGDPPEELPDFSEDPTSSGLLAAERAVSQVLDSLEEIHALTDCSEKDLDFLHSVFQDQHLHTLLDLYDKIN-TKSSPQIRNPPSDAVQRAKEVLEEISCYPENN------DAKELKRILTQPHFMALLQTHHVVAHEVYSDEALRVTPPPTSPYLNGDSPESANGDMDMENVTRVRLVQFQKNTDEPMGITLKMNELNHCIVARIMHGGMIHRQGTLHVGDEIREINGISVANQTVEQLQKMLREMRGSITFKIVPSYRTQSSSCERDSPSTSRQSPANGHSSTNNSVS------------IYVRAQFEYDPAKDDLIPCKEAGIRFRVGDIIQIISKDDHNWWQGKLENSKNGTAGLIPSPELQEWRVACIAMEKTKQEQQASCTWFGKKKKQYKDKYLAKHN-----ADLVTYEEVVKLPA----FKRKTLVLLGAHGVGRRHIKNTLITKHPERFAYPIPHTTRPPKKDEENGKNYYFVSHDQMMQDISNNEYLEYGSHEDAMYGTKLETIRKIHEQGLIAILDVEPQALKVLRTAEFPPFVVFIAAPTIT--PGLNE---------DESLQRLQKESDVLQRTYAHYFDLTIINNEIDETIRHLEEAVELVCTAPQWVPVSWVY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70589-1", "uniprot_id": "CSKP_MOUSE", "id": "O70589-1", "name": "Peripheral plasma membrane protein CASK", "aln": "MADDDVLFEDVYELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTEDLKREASICHMLKHPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILEALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLG--ESGLVAGGRVGTPHFMAPEVVKREPYGKPVDVWGCGVILFILLSGCLPFYGTKERLFEGIIKGKYKMNPRQWSHISESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYAYKIHLPETVEQLRKFNARRKLKGAVLAAVSSHKFNSFYGDPPEELPDFSEDPTSSGLLAAERAVSQVLDSLEEIHALTDCSEKDLDFLHSVFQDQHLHTLLDLYDKIN-TKSSPQIRNPPSDAVQRAKEVLEEISCYPENN------DAKELKRILTQPHFMALLQTHDVVAHEVYSDEALRVTPPPTSPYLNGDSPESANGDMDMENVTRVRLVQFQKNTDEPMGITLKMNELNHCIVARIMHGGMIHRQGTLHVGDEIREINGISVANQTVEQLQKMLREMRGSITFKIVPSYRTQSSSCERDSPSTSRQSPANGHSSTNNSVSDLPSTTQPKGRQIYVRAQFEYDPAKDDLIPCKEAGIRFRVGDIIQIISKDDHNWWQGKLENSKNGTAGLIPSPELQEWRVACIAMEKTKQEQQASCTWFGKKKKQYKDKYLAKHNAVFDQLDLVTYEEVVKLPA----FKRKTLVLLGAHGVGRRHIKNTLITKHPDRFAYPIPHTTRPPKKDEENGKNYYFVSHDQMMQDISNNEYLEYGSHEDAMYGTKLETIRKIHEQGLIAILDVEPQALKVLRTAEFAPFVVFIAAPTIT--PGLNE---------DESLQRLQKESDVLQRTYAHYFDLTIINNEIDETIRHLEEAVELVCTAPQWVPVSWVY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14936-1", "uniprot_id": "CSKP_HUMAN", "id": "O14936-1", "name": "Peripheral plasma membrane protein CASK", "aln": "MADDDVLFEDVYELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTEDLKREASICHMLKHPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILEALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLG--ESGLVAGGRVGTPHFMAPEVVKREPYGKPVDVWGCGVILFILLSGCLPFYGTKERLFEGIIKGKYKMNPRQWSHISESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYAYKIHLPETVEQLRKFNARRKLKGAVLAAVSSHKFNSFYGDPPEELPDFSEDPTSSGLLAAERAVSQVLDSLEEIHALTDCSEKDLDFLHSVFQDQHLHTLLDLYDKIN-TKSSPQIRNPPSDAVQRAKEVLEEISCYPENN------DAKELKRILTQPHFMALLQTHDVVAHEVYSDEALRVTPPPTSPYLNGDSPESANGDMDMENVTRVRLVQFQKNTDEPMGITLKMNELNHCIVARIMHGGMIHRQGTLHVGDEIREINGISVANQTVEQLQKMLREMRGSITFKIVPSYRTQSSSCERDSPSTSRQSPANGHSSTNNSVSDLPSTTQPKGRQIYVRAQFEYDPAKDDLIPCKEAGIRFRVGDIIQIISKDDHNWWQGKLENSKNGTAGLIPSPELQEWRVACIAMEKTKQEQQASCTWFGKKKKQYKDKYLAKHNAVFDQLDLVTYEEVVKLPA----FKRKTLVLLGAHGVGRRHIKNTLITKHPDRFAYPIPHTTRPPKKDEENGKNYYFVSHDQMMQDISNNEYLEYGSHEDAMYGTKLETIRKIHEQGLIAILDVEPQALKVLRTAEFAPFVVFIAAPTIT--PGLNE---------DESLQRLQKESDILQRTYAHYFDLTIINNEIDETIRHLEEAVELVCTAPQWVPVSWVY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6Z057-1", "uniprot_id": "A0A8M6Z057_DANRE", "id": "A0A8M6Z057-1", "name": "Peripheral plasma membrane protein CASK", "aln": "MADDDVLFEDVYELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTEDLKREASICHMLKHPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILEALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLG--ESGLVAGGRVGTPHFMAPEVVKREPYGKPVDVWGCGVILFILLSGCLPFYGTKERLFEAIIKGKYKMNPRQWGHISESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYAYKIHLPETVEQLRKFNARRKLKGAVLAAVSSHKFNSFYGDPPEELPDFSEDPTSSGLLAAERAVSQVLDSLEEIHALTDCSEKDLDFLHSVFQDHHLHTLLDLYDKIN-TKSSPQIRNPSSDAVQRAKEVLEEISCYPENT------DAKELRRILTQPHFMALLQTHDVVAHEVYSDDAMRVTPPPTSPYLNGDSPESTNGDMDIENVTRVRLVQFQKNTDEPMGITLKMNDLNHCIVARIMHGGMIHRQGTLHIGDEIREINGISVANQTVEQLQKMLREMRGSITFKIVPSYRTQQSSCEKESPSTSRQSPANGHSSINSSILDLPSTIQPKGRQIYVRAQFEYDPVKDDLIPCKEAGIRFRVGDIIQIINKDDHNWWQGKLENTKNGTAGLIPSPELQEWRVACIAMEKTKQEQQASCTWFGKKKKQYKDKYLAKHNAVFDQLDLVTYEEVVKLPA----FKRKTLVLLGAHGVGRRHIKNTLITKHPDRFAYPIPHTTRPPKKDEENGKNYFFVSHDQMMQDISNNDYLEYGSHEDAMYGTRLETIRKIHEQGLIAILDVEPQALKVLRTAEFAPYVVFIAAPTIT--PGMNELPRWCRKLPDESLQRLQKESEILQKTYAHYFDQTIINNEIDETIRLLEEAIDMVCSTAQWVPVSWVY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24210-3", "uniprot_id": "CSKP_DROME", "id": "Q24210-3", "name": "Peripheral plasma membrane protein CASK", "aln": "MTEDEILFDDVYELCEVIGKGPFSIVRRCIHRESNQQFAVKIVDVAKFTASPGLSTADLKREATICHMLKHPHIVELLETYSSEGMLYMVFEFMEGSDLCFEVVRRAVAGFVYSEAVACHYMRQILEALRYCHENDILHRDVRPACALLATVDNSAPVKLGGFGSAIQLPGTRETIETHGRVGCPHYMAPEVVTRRLYGKGCDVWGAGVMLHVLLSGRLPFLGSGVRLQQSVARGRLSFEAPEWKSISANAKDLVMKMLAANPHHRLSITEVLDHPWIRDRDK-LQRTHLADTVEELKRYNARRKLKGAVQAIAGGTNMDPLYAT-DADMPITGATDEWADEEAGIEAVQRILDCLDDIYSLQDAH-VDADVLRDMLRDNRLHQFLQLFDRIAATVVTSNGRAPAAEAVGRCRDVLEQLSSTSGGNSLGGKYAKEELMRLLAAPHMQALLHSHDVVARDVYGEEALRVTPPPMVPYLNGDELDNVEG-GELQHVTRVRLVQFQKNTDEPMGITLKMTEDGRCIVARIMHGGMIHRQATLHVGDEIREINGQPVQHQSVGQLQRMLREARGSVTFKIVPSYRSAPPPCE-----------------------------------IFVRAQFDYNPLDDELIPCAQAGISFQVGDILQIISKDDHHWWQARLDTVG-GSAGLIPSPELQEWRIACQTVDKTKQEQ-VNCSIFGRKKKQCRDKYLAKHNAIFDTLDVVTYEEVVKVPVGDPNFQRKTLVLLGAHGVGRRHIKNTLISKYPDKYAYPIPHTTRPAKPEEENGRSYYFVSHDEMMADIGANEYLEYGTHEDAMYGTKLDTIRRIHTEGKMAILDVEPQALKILRTAEFTPYVVFIAAPSLQNIADY-----------DGSLERLAKESEMLRQLYGHFFDLTIVNNDISETIATLETAIDRVHTTPQWVPVSWLY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*::*::**:***************:*****:**:.**************:****** ******:*******************:**********:*:*****:*:** **********.**************:*:*:****:* *.***: :*********** **** .. : : **** **:******.*. *** ****.**:*.:**** *** *: ** :.: :*: .::. :* ** .***** :** :* .*::: *.*:***:::**: : **.:***:*:::********** * ... :::.:*. ::* . :. *. .**.::**.*::*::* *. * *.*:.:::*::** :*:*:*:* * :.: * *.::** *.::***::*. . .. :** *:*: **: ***::*.***::**.::*:****** ******. :..:* ::::***********************.: .:***************.***:********* .* :*:* ***:**** ***:*********: ..** *:*****:*:* .*:**** :*** *:****:***.****:***.:*:. *:*************:** :::****** ..*: **:**** :******** *:********:*. *:**********************:*:*:::**********.* :****:.*:*****:** **. *:*****:********:*:***:** :* :***********:******.*:*******:: .. * **:** ***::*:: *.*:** **:**:*.*** ** *:: * ::.*******:*", "identical_positions": 552, "similar_positions": 224, "identity": "58.11%" }, { "cls_id": "homologset.agr.MGI:1309503", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88943-1", "uniprot_id": "KCNQ2_RAT", "id": "O88943-1", "name": "Potassium voltage-gated channel subfamily KQT member 2", "aln": "MVQKSRNGGVYPGTSGEKKLKVGFVGLDPGAPDSTRDGALLIAGSEAPKRGSVLSKPRTGGAGAGKPPKRNAFYRKLQNFLYNVLERPRG-WAFIYHAYVFLLVFSCLVLSVFSTIKEYEKSSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEKGENDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTWQYYERTVTVPMISSQTQTYGASRLIPPLNQLEMLRNLKSKSGLTFRKEPQPEPSPS------------------QKVSLKDRVFSSPRGVAAKGKGSPQAQTVRRSPSADQSLDDSPSKVPKSWS----FGDRSRAR-QAFRIKGAASRQNSEEASLPG-----------------------------------------------------------------------------------------------EDIVEDNKSCNCEFVTEDLTPGLKVSIRAVCVMRFLVSKRKFKESLRPYDVMDVIEQYSAGHLDMLSRIKSLQS------------------------------------RVDQIVGRGPTITDKDRTKGPAETELPEDPSMMGRLGKVEKQVLSMEKKLDFLVSIYTQRMG---IPPAETEAYFGAKEPEPAPPYHSPEDSRDHADKHGCIIKIVRSTSSTGQRKYAAPP------VMPPAECPPSTSWQ-QSHQR---HGTSPVGDHGSLVRIPPPPAHERSLSAYSGGNRASTEFLRLEGTPACRPSEAALRDSDTSISIPSVDHEELERSFSGFSISQSKENLNALASCYAAVAPCAKVRPYIAEGESDTDSDLCTPCGPPPRSATGEGPFGDVAWAGPRK--------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O43526-1", "uniprot_id": "KCNQ2_HUMAN", "id": "O43526-1", "name": "Potassium voltage-gated channel subfamily KQT member 2", "aln": "MVQKSRNGGVYPGPSGEKKLKVGFVGLDPGAPDSTRDGALLIAGSEAPKRGSILSKPRAGGAGAGKPPKRNAFYRKLQNFLYNVLERPRG-WAFIYHAYVFLLVFSCLVLSVFSTIKEYEKSSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEKGENDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTWQYYERTVTVPMYSSQTQTYGASRLIPPLNQLELLRNLKSKSGLAFRKDPPPEPSPSKGSPCRGPLCGCCPGRSSQKVSLKDRVFSSPRGVAAKGKGSPQAQTVRRSPSADQSLEDSPSKVPKSWS----FGDRSRAR-QAFRIKGAASRQNSEEASLPG-----------------------------------------------------------------------------------------------EDIVDD-KSCPCEFVTEDLTPGLKVSIRAVCVMRFLVSKRKFKESLRPYDVMDVIEQYSAGHLDMLSRIKSLQS------------------------------------RVDQIVGRGPAITDKDRTKGPAEAELPEDPSMMGRLGKVEKQVLSMEKKLDFLVNIYMQRMG---IPPTETEAYFGAKEPEPAPPYHSPEDSREHVDRHGCIVKIVRSSSSTGQKNFSAPP------AAPPVQCPPSTSWQPQSHPRQG-HGTSPVGDHGSLVRIPPPPAHERSLSAYGGGNRASMEFLRQEDTPGCRPPEGNLRDSDTSISIPSVDHEELERSFSGFSISQSKENLDALNSCYAAVAPCAKVRPYIAEGESDTDSDLCTPCGPPPRSATGEGPFGDVGWAGPRK--------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Z351-1", "uniprot_id": "KCNQ2_MOUSE", "id": "Q9Z351-1", "name": "Potassium voltage-gated channel subfamily KQT member 2", "aln": "MVQKSRNGGVYPGTSGEKKLKVGFVGLDPGAPDSTRDGALLIAGSEAPKRGSVLSKPRTGGAGAGKPPKRNAFYRKLQNFLYNVLERPRG-WAFIYHAYVFLLVFSCLVLSVFSTIKEYEKSSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEKGENDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFALKVQEQHRPKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTWQYYERTVTVPMY----------RLIPPLNQLELLRNLKSKSGLTFRKEPQPEPSPS------------------QKVSLKDRVFSSPRGMAAKGKGSPQAQTVRRSPSADQSLDDSPSKVPKSWS----FGDRSRTR-QAFRIKGAASRQNSEEASLPG-----------------------------------------------------------------------------------------------EDIVEDNKSCNCEFVTEDLTPGLKVSIRAVCVMRFLVSKRKFKESLRPYDVMDVIEQYSAGHLDMLSRIKSLQSRIDMIVGPPPPSTPRDKKYPTKGPTAPSRESPQYSPRVDHIVGRGPTITDKDRTKGPAETELPEDPSMMGRLGKVEKQVLSMEKKLDFLVSIYTQRMG---IPPAETEAYFGAKEPEPAPPYHSPEDSRDHADKHGCIIKIVRSTSSTGQRNYAAPP------AIPPAQCPPSTSWQ-QSHQR---HGTSPVGDHGSLV-------------------------LR------------------------------LERSAG-------------MMSCH-----------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A1Z856-1", "uniprot_id": "A1Z856_DROME", "id": "A1Z856-1", "name": "", "aln": "-MDPDNDIYAFYDIRGYKGKCR------PGRPNSER---------ILQPRMSLLGKPLN----YNRGTRRDVRYRRLQSRLYNFLERPRGLHAIFYHVMVFLMVFTCLALSVFSTIKEYEEDAVYILFRMEILVVIWFTMEFGARLWSSGCRSRYQGCLGRLKFVKRPFCIIDIVTILASIVVLGMGTSGQVFATSALRGLRFFQILRMVRMDRRGGTWKLLGSVVYAHRQELITTMYIGFLGLIFASFLVYMWEKDVNDKFSNFAQALWWGVITLCTVGYGDMVPITWQGKLIASCCALLGISFFALPAGILGSGFALKVQQQQRQKHMIRRRQPAATLIQAVWRCYAADEHSVSVATWNIHRVALPSPPASRASSSFKHNTSFVARLPTIRRHKSQTIQTPGGGDGGGVSKPPGSSRASTRYTRTIRDINASVENLEVVQNGKSMNPSFSEDSVAETTCLKNIKNSDASQPATLANCKLSSSAGSLAQFPDRNRDRDQDRRGHGEGEGDQAEEQAKAGGSRRNLTIPVVLYGFLHGNFLGSTLSLRNPRVAPANDRDLEAGRDEDEVHKDTCQRSNTLPLPVKPDSPSGSPGSGRTGRFFAAASHFLETGFSSPNPIIDVANEEDEPRCTQLTNRHKTAIRFIRKLKYFVARRKFKEALKPYDVKDVMEQYAAGHVDLLGRVKMLHL------------------------------------RLDQILGK---------QGSKAKDVYASKISLASRVVKVERQVADIEEKLDILIKAYMEDRDRFLALPLPAKPKIHSISPSHKPLHHAHNLAMIDVWKRTAALSVHPEQVTTTPLLNPSAPDSSELRSLTATQTPTTTTDAIATQTPMPPHVQHTATNTKSSVLNSYQLGSEKQQHNDVFMTELENRTKKRVTLSLHRSTSEPYSKQEQRITIPDEGADSLDSSAKPTPPDSSIILIDEYEDFEEEDLNCEGEMDHFPTWEIDSDIGVEVDVDADADGDCDESTEDTALLQCATRTAIVITPISPVSSAHNLQQLNDQTTTLNKSNLLPPDSG", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: ..: .: . * * ** *:* * * *:*.** .: .:*:. **:**. ***.****** *::**. ***:**:**.***********:.: *: :**:.:: * :*: .*:*::** .**:* *****.::***:***:.::***.**. *:.*:********.***:*****:******************* :**:*: ***** **:******: **. **:*..:*:*****:*** *:**** * **:*:*:*: :*:*:*******************:*:* **: :**:*** ***:.** **:: ..: : : : * ::. * :. :. . :: .:*. * :::.: :. * ..: .. ... . . :...*.*. : .*:..* . * **.* * * * :* .. :::** : .* : : * . * :** *.:** : ::::*::*****:*:**** **:***:***:*:*.*:* *: *:*:*:*: . *: ... *: .*: ***:** .:*:***:*:. * : . * ::. : : .*. * :*: : : .. :: . :.: . :* .:.* ...: *.:*: :: * .. : * * : *: * . ", "identical_positions": 272, "similar_positions": 227, "identity": "25.71%" }, { "cls_id": "homologset.agr.MGI:1309511", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A8S5-1", "uniprot_id": "D4A8S5_RAT", "id": "D4A8S5-1", "name": "Cell division cycle 7-related protein kinase", "aln": "--------------------------------------------------------------------------------------------MEEPMAFSPLRGCDRCPADDSLKKYEQSVKLS-GIKRDIEELCEAVPQLVSVFKIKDKIGEGTFSSVYLA-------TAQLQ----EGREEKIALKHLIPTSHPVRIAAELQCLTVAGGQDNVMGVKYCFRKNDHVVIAMPYLEHESFLDILNSLSFQEVREYMFNLFVALKRIHQFGIVHRDVKPSNFLYNRRLKKYALVDFGLAQGTRDTKIELLKFVQSEAQQEDCSRNKCHGVIGHKGPLSR--PAPKNVDQHITTKTSVKRSYANAQIHIKQGKDGKEGSVGLSVQRSVFGE----------------RNFNIHSSISHES-PAEKLIKQSKTVDIMSRKLATKKM-AVSTKAVN-SSMRDSARS-------CPAALTCDCYGTDRVCSVCLSRRQQVAPRAGTPGFRAPEVLTKCPDQTTAIDMWSAGVIFLSLLSGRYPFYKASDDLTALAQIMTIRGSRETIQAAKAFGKSILCS------KEVPAQDLRTLCERLRGPDSANPKSAVDPPGNTGHHPAASESTDHKAP-HAPASPAQHSEDSLYKRGSGGGRRHPRDRTANPEGWDSVPDDAYDLLDKLLDLNPASRITAEAALVHPFFKDVC----------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z0H0-1", "uniprot_id": "CDC7_MOUSE", "id": "Q9Z0H0-1", "name": "Cell division cycle 7-related protein kinase", "aln": "--------------------------------------------------------------------------------------------MEEPMAFSSLRGSDRCPADDSLKKYEQSVKLS-GIKRDIEELCEAVPQLVNVFKIKDKIGEGTFSSVYLA-------TAQLQ----EGHEEKIALKHLIPTSHPMRIAAELQCLTVAGGQDNVMGLKYCFRKNDHVVIAMPYLEHESFLDILNSLSFQEVREYMYNLFVALKRIHQFGIVHRDVKPSNFLYNRRLKKYALVDFGLAQGTRDTKIELLKFVQSEAQQEDCSRNKYHGVVGHKGLLSR--PAPKTVDQQCTPKTSVKRSYT--QVHIKQGKDGKERSVGLSVQRSVFGE----------------RNFNIHSSISHES-PAEKLIKQSKTVDIISRKLATKKT-AISTKAMN-SVMRETARS-------CPAVLTCDCYGSDRVCSVCLSRRQQVAPRAGTPGFRAPEVLTKCPDQTTAIDMWSAGVIFLSLLSGRYPFYKASDDLTALAQIMTIRGSRETIQAAKAFGKSVLCS------KEVPAQDLRALCERLRGLDSTTPRSASGPPGNASYDPAASKNTDHKAS-RVQAAQAQHSEDSLYKRDNDGYWSHPKDCTSNSEGWDSVPDEAYDLLDKLLDLNPASRITAEAALLHAFFKDMCS---------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00311-1", "uniprot_id": "CDC7_HUMAN", "id": "O00311-1", "name": "Cell division cycle 7-related protein kinase", "aln": "------------------------------------------------------------------------------------MEASLGIQMDEPMAFSPQR--DRFQAEGSLKKNEQNFKLA-GVKKDIEKLYEAVPQLSNVFKIEDKIGEGTFSSVYLA-------TAQLQ----VGPEEKIALKHLIPTSHPIRIAAELQCLTVAGGQDNVMGVKYCFRKNDHVVIAMPYLEHESFLDILNSLSFQEVREYMLNLFKALKRIHQFGIVHRDVKPSNFLYNRRLKKYALVDFGLAQGTHDTKIELLKFVQSEAQQERCSQNKSHIITGNKIPLSG--PVPKELDQQSTTKASVKRPYTNAQIQIKQGKDGKEGSVGLSVQRSVFGE----------------RNFNIHSSISHES-PAVKLMKQSKTVDVLSRKLATKKK-AISTKVMNSAVMRKTASS-------CPASLTCDCYATDKVCSICLSRRQQVAPRAGTPGFRAPEVLTKCPNQTTAIDMWSAGVIFLSLLSGRYPFYKASDDLTALAQIMTIRGSRETIQAAKTFGKSILCS------KEVPAQDLRKLCERLRGMDSSTPKLTSDIQGHASHQPAISEKTDHKASCLVQTPPGQYSGNSFKKGDSNSCEHCFDEYNTNLEGWNEVPDEAYDLLDKLLDLNPASRITAEEALLHPFFKDMSL---------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0UYI0-1", "uniprot_id": "B0UYI0_DANRE", "id": "B0UYI0-1", "name": "non-specific serine/threonine protein kinase", "aln": "--------------------------------------------------------------------------------------------MEE--ANTVQR-----SSHRSVEKGRSRHKISRDVETEIAYLYEVLPQLSRIFRIIDKIGEGTFSSVYLA-------EAQMT----DSSRRLFALKHLIPTSHPVRIAAELQCLTVAGGTENVMGVTYCFRKEHHVVIVMPYMEHQTFVDIVGLLSFEDVRHYIYHLLKALKHIHKFGIIHRDIKPTNFLFNRQKREYALVDFGLAQGTPDTQIELLKVVKSKGHKGGGSSKMVEESLGKQKLVPLP-PNSRNPAVQSSTKAPAKRPCPPSRVKHSKELMGLDKAP-----RSVFGE----------------KSINSTNSHKPGSDKVEGLLSKPKKEEVIPRKIVSAKHRSVPVRAPLNQKQKLPAESQKPKPAAVNPLLTCNCYMTDRVCNICLSRKQQVAPRAGTPGFRAPEVLTKCPNQGTAIDMWSAGVILLSLLSGRYPFFKANDDLIALTQIMTIRGSKETIEAAKTFGKSIVCS------RELPRLDLRILCETLRGLRSWDDASLP-AEFQASHNPAEEKEE--------AESPALKSTGSRLCRSS---------AELKEIGWDRVPDEVYDLLDKLLDLNPATRITASTALQHPLFKDMSE---------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W3Y1-1", "uniprot_id": "CDC7_DROME", "id": "Q9W3Y1-1", "name": "non-specific serine/threonine protein kinase Cdc7", "aln": "MADR---VMCQELATPGSHYRRPK--TGVPSTNVVYANG----GGSWRAAPRQTQRLPRQTVQQYATGTPATGSAGRHSGR--------AFATAGATEEQTVEFNG-AAVMGLPATPRTTKQARNKSEEAINDLLTRIPDIGKLFDVHSRIGNGTFSTVLLG-------TLRRESHLPDSLRRKFAIKHHIPTSHPDRIMKELQCMTKMGGKENVVGIHCCMRYDASAAFVMPFMAHDRFQDFYTRMDVPEIRQYMRNLLVALRHVHKFDVIHRDVKPSNFLYNRRRREFLLVDFGLAQHVNPPAARSSGSAAAIAAANNKNNNNNNNNNSKRPRERESKGDVQQIALDAGLGGAVKRMRLHEESNKMPLKPVNDIAPSDAPEQSVDGSNHVQPQLVQQEQQQLQPQQQQQQQQQQQQSQQQQQPQQQSQQQHPQRQPQLAQMDQTASTPSGSKYNTNRNVSA-----AAANNAKCVCFANPSVCLNCLMKKEVHASRAGTPGYRPPEVLLKYPDQTTAVDVWAAGVIFLSIMSTVYPFFKAPNDFIALAEIVTIFGDQAIRKTALALDRMITLS------QRSRPLNLRKLCLRFRYRSVFSDAKLLKSYESVDGSCEVCRNCDQYFFNCLCEDSDYLTEP--------------------LDAYECFPPSAYDLLDRLLEINPHKRITAEEALKHPFFTAAEEAEQ----TEQDQLANGTPRKMRRQRYQ--SHRTVAASQE-QVKQQVALDLQQAAINKL-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VJ90-1", "uniprot_id": "CDC7B_DROME", "id": "Q9VJ90-1", "name": "non-specific serine/threonine protein kinase", "aln": "MDKKEVQHHRSQQAMTKSLYAIGMGLLGKSATNMDCANTNLESAGKSSSTNYNRNRFYNERFVPMASGTMPSVSGTNHHSRHQQLLLQQAPKCTADLNEKLVKINRQNANKELSTIQAKDMQSVDKNEEALKELQESIPEINKIFDVHCRIGSGTFSTVLLG-------TLQRERGLVETQRRRFAIKHHNPTNHPERILRELECMYRIGGVENVIGINCCIRYNDNVAFIMPYMTHDRFHDIYRSLNFPEIRDYLRNLLIALRHVHKFNVIHRDVKPSNILYNRRTGKFLLCDFGLAQRIADDGSVVQSSDLSSREVFSILRDLENG---------------RSVTLTDGNS------AQAEAEDYMARRRMRALGGGGSVERAVTGP----------------PSIQKLREQAGGHLTKKDVANQRADTMR-----LLNRLRLVSPNADPNNYVVSTNTS----------------------------KKEMHASRAGTPGYRPPEVLLRYPKQSTAVDVWAAGVIMLSLLSGLHPFFKAPHDCGALAEIINLFGDMPVRKTAFLLDRLILLA------QKVNTLDLRRVCMRFRHADFFLAPEIQRKYQRPDGTTEMCRSCEQPTFNCLCSNSGHNLER--------------------YDGLDIFPAVAYDLLSRLLEVNPQKRITAEEALKHPFFSDQHRITPGIPLHQQQLIMHQQQHIMQHQQHLQRSRETLPSSAARTLKAFVCYPMEITSTASQAAGNI", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P06243-1", "uniprot_id": "CDC7_YEAST", "id": "P06243-1", "name": "Cell division control protein 7", "aln": "----------------------------------------------------------------------------------------------------------------MTSKTKNIDDIPPEIKEEMIQLYHDLPGIENEYKLIDKIGEGTFSSVYKAKDITGKITKKFASHFWNYGSNYVALKKIYVTSSPQRIYNELNLLYIMTGSSRVAPLCDAKRVRDQVIAVLPYYPHEEFRTFYRDLPIKGIKKYIWELLRALKFVHSKGIIHRDIKPTNFLFNLELGRGVLVDFGLAEAQMDYKSMISSQNDYDNYANTNHDG----------------------------------------------------------------------------------GYSMRNHEQFCPCIMRNQYSPNSHNQTPPMVTIQNGKVVHLNNVNGVDLTKGYPKNE--------------------------TRRIKRANRAGTRGFRAPEVLMKCGAQSTKIDIWSVGVILLSLLGRRFPMFQSLDDADSLLELCTIFGWKELRKCAALHGLGFEASGLIWDKPNGYSNGLKEFVYDLLNKECTIGTFPEYSVAFETFGFLQQELHDRMSIEPQLPDPKTNMDAVDAYELK-----------KYQEEIWSDHYWCFQVLEQCFEMDPQKRSSAEDLLKTPFFNELNENTYLLDGESTDE------------------DDVVSSSEADLLDKDVLLISE------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : * :* : : : :**.****:* . : . .*:*: *. * ** **: : * ..* : . * . :*: *: * : : . ::.*: .*: **: :*. .::***:**:*:*:* . . * *****: . . . :: * **** *:*.**** : * * :*:*:.***:**::. .*:::: .* :* :: .: * : * . . : . .*: . : . :::*.: ::::* .* :*. * .:*. ", "identical_positions": 74, "similar_positions": 101, "identity": "9.64%" }, { "cls_id": "homologset.agr.MGI:1309515", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P14942-1", "uniprot_id": "GSTA4_RAT", "id": "P14942-1", "name": "Glutathione S-transferase alpha-4", "aln": "------MEVKPKLYYFQG---RGRMESIRWLLATAGVEFEEEFLETREQYEKLQKDGCLLFGQVPLVEIDGMLLTQTRAILSYLAAKYNLYGKDLKERVRIDMYADGTQDLMMMIIGAPFKAPQEKEESLALAVKRAKNRYFPVFEKILKDHGEAFLVGNQLSWADIQLLEAILMVEEVSAPVLSDFPLLQAFKTRISNIPTIKKFLQPGSQRKPPPDGHYVDVVRTVLKF---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P24472-1", "uniprot_id": "GSTA4_MOUSE", "id": "P24472-1", "name": "Glutathione S-transferase A4", "aln": "------MAAKPKLYYFNG---RGRMESIRWLLAAAGVEFEEEFLETREQYEKMQKDGHLLFGQVPLVEIDGMMLTQTRAILSYLAAKYNLYGKDLKERVRIDMYADGTQDLMMMIAVAPFKTPKEKEESYDLILSRAKTRYFPVFEKILKDHGEAFLVGNQLSWADIQLLEAILMVEELSAPVLSDFPLLQAFKTRISNIPTIKKFLQPGSQRKPPPDGPYVEVVRTVLKF---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AC58H0S2-1", "uniprot_id": "A0AC58H0S2_DANRE", "id": "A0AC58H0S2-1", "name": "glutathione transferase", "aln": "MSVIYFRGCTIIIIFPLGNLFWANMSFRLNFAFVCSSQFEEVFLTEKEQFDKLLSDGALTFQQVPLVEIDGMKLVQSKAILNYIAGKYNLYGKDLKERAMIDIYSEGLIDLMEMIMVSPFTPAENKEKVFSNIEEKAKVRFLPVFEKALANS--SFLVGKQLSRADVHLLEATLMLQELFPSILATFPKIQAFQEQMKALPAISKFLQPGSARKPPPDEEYARTVKAVLSHLFK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : * ..*. : ... :*** ** :**::*: .** * * ********** *.*::***.*:*.************. **:*::* *** ** :**...::**: .:** *::***** * : :****:*** **::**** **::*: ..:*: ** :***: ::. :*:*.******* ****** *. .*::**.. ", "identical_positions": 106, "similar_positions": 63, "identity": "45.3%" }, { "cls_id": "homologset.agr.MGI:1309516", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5RJS8-1", "uniprot_id": "TPST2_RAT", "id": "Q5RJS8-1", "name": "Protein-tyrosine sulfotransferase 2", "aln": "MRLSVR--KVLLAVGCALALVLAVQLGQQVLECRAVLGGVRSPR-RMQPEQEELVMLGADHVEYRYGKTMPLIFVGGVPRSGTTLMRAMLDAHPEVRCGEETRIIPRVLAMRQAWTKSGREKLRLDEAGVTDEVLDAAMQAFILEVIAKHGEPARVLCNKDPFTLKSSVYLARLFPNSKFLLMVRDGRASVHSMITRKVTIAGFDLSSYRDCLTKWNKAIEVMYAQCMEVGRDKCLPVYYEQLVLHPRRSLKRILDFLGIAWSDTVLHHEDLIGKPGGVSLSKIERSTDQVIKPVNLEALSKWTGHIPRDVVRDMAQIAPMLARLGYDPYANPPNYGNPDPIVINNTHRVLKGDYKTPANLKGYFQVN---QNSTSPHLGSS---------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88856-1", "uniprot_id": "TPST2_MOUSE", "id": "O88856-1", "name": "Protein-tyrosine sulfotransferase 2", "aln": "MRLSVR--KVLLAAGCALALVLAVQLGQQVLECRAVLGGTRNPR-RMRPEQEELVMLGADHVEYRYGKAMPLIFVGGVPRSGTTLMRAMLDAHPEVRCGEETRIIPRVLAMRQAWTKSGREKLRLDEAGVTDEVLDAAMQAFILEVIAKHGEPARVLCNKDPFTLKSSVYLARLFPNSKFLLMVRDGRASVHSMITRKVTIAGFDLSSYRDCLTKWNKAIEVMYAQCMEVGRDKCLPVYYEQLVLHPRRSLKRILDFLGIAWSDTVLHHEDLIGKPGGVSLSKIERSTDQVIKPVNLEALSKWTGHIPRDVVRDMAQIAPMLARLGYDPYANPPNYGNPDPIVINNTHRVLKGDYKTPANLKGYFQVN---QNSTSPHLGSS---------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60704-1", "uniprot_id": "TPST2_HUMAN", "id": "O60704-1", "name": "Protein-tyrosine sulfotransferase 2", "aln": "MRLSVR--RVLLAAGCALVLVLAVQLGQQVLECRAVLAGLRSPRGAMRPEQEELVMVGTNHVEYRYGKAMPLIFVGGVPRSGTTLMRAMLDAHPEVRCGEETRIIPRVLAMRQAWSKSGREKLRLDEAGVTDEVLDAAMQAFILEVIAKHGEPARVLCNKDPFTLKSSVYLSRLFPNSKFLLMVRDGRASVHSMITRKVTIAGFDLSSYRDCLTKWNKAIEVMYAQCMEVGKEKCLPVYYEQLVLHPRRSLKLILDFLGIAWSDAVLHHEDLIGKPGGVSLSKIERSTDQVIKPVNLEALSKWTGHIPGDVVRDMAQIAPMLAQLGYDPYANPPNYGNPDPFVINNTQRVLKGDYKTPANLKGYFQVN---QNSTSSHLGSS---------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VYB7-1", "uniprot_id": "TPST_DROME", "id": "Q9VYB7-1", "name": "Protein-tyrosine sulfotransferase", "aln": "MRLPYRNKKVTLWVLFGIIVITMFLFKFTELRPTCLFKVDAANELSSQMVRVEKYLTDDNQRVYSYNREMPLIFIGGVPRSGTTLMRAMLDAHPDVRCGQETRVIPRILQLRSHWLKSEKESLRLQEAGITKEVMNSAIAQFCLEIIAKHGEPAPRLCNKDPLTLKMGSYVIELFPNAKFLFMVRDGRATVHSIISRKVTITGFDLSSYRQCMQKWNHAIEVMHEQCRDIGKDRCMMVYYEQLVLHPEEWMRKILKFLDVPWNDAVLHHEEFINKPNGVPLSKVERSSDQVIKPVNLEAMSKWVGQIPGDVVRDMADIAPMLSVLGYDPYANPPDYGKPDAWVQDNTSKLKANRMLWESKAKQVLQMSSSEDDNTNTIINNSNNKDNNNNQYTINKIIPEQHSRQRQHVQQQHLQQQQQQHLQQQQHQRQQQQQQREEESESEREAEPDREQQLLHQKPKDVITIKQLPLAGSNNNNINNNINNNNNNNNIMEDPMADT", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***. * :* * . .: :: . : *. .:: . : : * : . :: * *.: *****:*******************:****:***:***:* :*. * ** :*.***:***:*.**:::*: * **:******** ******:*** . *: .****:***:*******:***:*:*****:********:*: ***:*****: ** ::*:::*: **********.. :: **.**.:.*.*:*****::*.**.**.***:***:***********:***.*:** *******:*****: **********:**:**. * :** :: . :: * :*:. ::.*.. :..* ", "identical_positions": 207, "similar_positions": 101, "identity": "41.48%" }, { "cls_id": "homologset.agr.MGI:1309517", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O89051-1", "uniprot_id": "ITM2B_MOUSE", "id": "O89051-1", "name": "Integral membrane protein 2B", "aln": "-MVKVTFNSALAQKEAKKDEPKSSEEALIVPPDAVAVDCKDPG---DVVPVGQRRAWCWCMCFGLAFMLAGV-----ILGGAYLYKYFALQPDDVYY---CGLKYIKDDVILN----------------------EPSADAPAARYQTIEENIKIFEE-DAVEFISVPVPEFADSDPANIVHDFNKKLTAYLDLNLDKCYVIPLNTSIVMPPKNLLELLINIKAGTYLPQSYLIHEHM-VITDRIENVDNLGFFIYRLCHDKETYKLQRRETIRGIQKREAS---NCFTIRHFENKFAVETLICS----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y287-1", "uniprot_id": "ITM2B_HUMAN", "id": "Q9Y287-1", "name": "Integral membrane protein 2B", "aln": "-MVKVTFNSALAQKEAKKDEPKSGEEALIIPPDAVAVDCKDPD---DVVPVGQRRAWCWCMCFGLAFMLAGV-----ILGGAYLYKYFALQPDDVYY---CGIKYIKDDVILN----------------------EPSADAPAALYQTIEENIKIFEE-EEVEFISVPVPEFADSDPANIVHDFNKKLTAYLDLNLDKCYVIPLNTSIVMPPRNLLELLINIKAGTYLPQSYLIHEHM-VITDRIENIDHLGFFIYRLCHDKETYKLQRRETIKGIQKREAS---NCFAIRHFENKFAVETLICS----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5XIE8-1", "uniprot_id": "ITM2B_RAT", "id": "Q5XIE8-1", "name": "Integral membrane protein 2B", "aln": "-MVKVTFNSALAQKEAKKDEPKSSEEALIAPPDAVAVDCKDPD---DVVPVGQRRAWCWCMCFGLAFMLAGV-----ILGGAYLYKYFALQPDDVYY---CGLKYIKDDVILS----------------------EPSADAPAARYQTIEENIKIFEE-DAVEFISVPVPEFADSDPANIVHDFNKKLTAYLDLNLDKCYVIPLNTSIVMPPRNLLELLINIKAGTYLPQSYLIHEHM-VITDRIENVDHLGFFIYRLCHDKETYKLQRRETIRGIQKREAS---NCFTIRHFENKFAVETLICS----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VPT9-1", "uniprot_id": "Q9VPT9_DROME", "id": "Q9VPT9-1", "name": "Integral membrane protein 2", "aln": "MTILGKLRGQPTDQEKVPLPMNLNDEALMHHGSLIAPKVAYSDNEADAESMVFNRPQHHCIKSFLLFLIAVVVMLLGVLGGWTLYRVYAPSHSSMRYHALCEIPYPEDSMEMARVYPRTVEPFALNWRSLLPELAQPMPNSGSLDESHFREDIELDGDSDDEGYARVDVPDFKDGRRGRFMHDFKENQSAIIDTTTGRCFIMPLDRDTTLPPTSFVDLIKKMSTGYYNIDTERVRRQMRVVMPRITDVSLISERIANECFDMKVYMMEK--FVSGVSKRSADPLPESAKYAEFMGKGVIEYDLANIAEVEAYEANEARQQA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .:.. :::* : .:***: . :* . .. *. .: .*. *: * *::* * :*** **: :* . ..: * * : * :*.: : :* .:: : . :.*:*:: : : : * **:* *. ..::***::: :* :* . .:*:::**: . .:** .:::*: ::.:* * :: ::.:* *: ** ::. :. * . *.* :.* ::: : *:.**.*. :. .* .* .:* :.. ", "identical_positions": 58, "similar_positions": 114, "identity": "18.07%" }, { "cls_id": "homologset.agr.MGI:1309526", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P08708-1", "uniprot_id": "RS17_HUMAN", "id": "P08708-1", "name": "Small ribosomal subunit protein eS17", "aln": "MGRVRTKTVKKAARVIIEKYYTRLGNDFHTNKRVCEEIAIIPSKKLRNKIAGYVTHLMKRIQRGPVRGISIKLQEEERERRDNYVPEVSALDQ----EIIEVDPDTKEMLKLLDFGSLSNLQVTQPTVGMNFKTPRGPV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P63276-1", "uniprot_id": "RS17_MOUSE", "id": "P63276-1", "name": "Small ribosomal subunit protein eS17", "aln": "MGRVRTKTVKKAARVIIEKYYTRLGNDFHTNKRVCEEIAIIPSKKLRNKIAGYVTHLMKRIQRGPVRGISIKLQEEERERRDNYVPEVSALDQ----EIIEVDPDTKEMLKLLDFGSLSNLQVTQPTVGMNFKTPRGAV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P04644-1", "uniprot_id": "RS17_RAT", "id": "P04644-1", "name": "Small ribosomal subunit protein eS17", "aln": "MGRVRTKTVKKAARVIIEKYYTRLGNDFHTNKRVCEEIAIIPSKNLRNKIAGYVTHLMKRIQRGPVRGISIKLQEEERERRDNYVPEVSALDQ----EIIEVDPDTKEMLKLLDFGSLSNLQVTQPTVGMNFKTPRGAV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0LH50-1", "uniprot_id": "A0ABK0LH50_RAT", "id": "A0ABK0LH50-1", "name": "Small ribosomal subunit protein eS17", "aln": "MSRVRTKTVRKAARVIIEKYYTRLGNDFHTNKRVCEEIAIIPSKNLRNKIAGYVTHLMKRIQRGPVRGISIKLQEEERERRDNYVPEVSALDQ----EIIEVDPDTKEMLTLLDFGRLSHLQVTQPTVGMNFETPLGAV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P17704-1", "uniprot_id": "RS17_DROME", "id": "P17704-1", "name": "Small ribosomal subunit protein eS17", "aln": "MGRVRTKTVKKAAKVIIEKYYTRLTLDFHTNKRICEEVAIIPTKPLRNKIAGYVTHLMGRLRHSQVRGISIKLQEEERERRDNYVPAVSALEQ----DIIEVDADTKEMLKLLDFHNIRGLQLTQPNT-NNFGRRN---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P14127-1", "uniprot_id": "RS17B_YEAST", "id": "P14127-1", "name": "Small ribosomal subunit protein eS17B", "aln": "MGRVRTKTVKRASKALIERYYPKLTLDFQTNKRLCDEIATIQSKRLRNKIAGYTTHLMKRIQKGPVRGISFKLQEEERERKDQYVPEVSALDLSRSNGVLNVDNQTSDLVKSLGLKLPLSVINVSAQRDRRYRKRN---", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P02407-1", "uniprot_id": "RS17A_YEAST", "id": "P02407-1", "name": "Small ribosomal subunit protein eS17A", "aln": "MGRVRTKTVKRASKALIERYYPKLTLDFQTNKRLCDEIATIQSKRLRNKIAGYTTHLMKRIQKGPVRGISFKLQEEERERKDQYVPEVSALDLSRSNGVLNVDNQTSDLVKSLGLKLPLSVINVSAQRDRRYRKRV---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.*******::*::.:**:**.:* **:****:*:*:* * :* ********.**** *:::. *****:*********:*:*** ****: :::** :*.:::. *.: : ... .: ", "identical_positions": 64, "similar_positions": 41, "identity": "46.04%" }, { "cls_id": "homologset.agr.MGI:1309528", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q10728-1", "uniprot_id": "MYPT1_RAT", "id": "Q10728-1", "name": "Protein phosphatase 1 regulatory subunit 12A", "aln": "-----MKMADAKQKRNEQLKRWIGSETDLEPPVVKRQK-TKVKFDDGAVFLAACSSGDTDEVLKLLHRGADINYANVDGLTALHQACIDDNVDMVKFLVENGANINQPDNEGWIPLHAAASCGYLDIAEFLIGQGAHVGAVNSEGDTPLDIA---EEEAMEELLQNEVNRQGVDIEAARKEEERIMLRDARQWLNSGHISDVR-HAKSGGTALHVAAAKGYTEVLKLLIQAGYDVNIKDYDGWTPLHAAAHWGKEEACRILVDNLCDMETVNKVGQTAFDVADEDILGYLEELQKKQN---------------LLHSEKRD-KKSPLIESTANMENNQPQKTFKNKETLIIEPEKNASRIESLEQEKADEEE------------------------------------------------------------EGKKDESSCSSEEDEEDDSESEAETDKTKP-MASVTNAHTASTQAAPAAVTTPTLSSNQG---TPTSPVKKFPTSTTKISPKEEERKDESPASWRLG----------------------LRKTGSYGALAEITASKEAQKEKDTAGVIRSASSPRLSSSLDNKEKEKDNKGTRLAYVAPTIPRRLGSTSDIEEKENRE-SSNLRTSSSYTRRKWEDDLKKN-----------------------SSINEGSTYHRSCS----FGRRQD--DLISCSVPSTTSTPTVTSAAG---------LQKS---------FLSSTSTTAKTPPGSSPAGTQS--------------------------------------STSNRLWAEDSTEKEKDSAPTAATILVAPTVVSAAASSTTALTTTTAGTLSSTSEVRERRRSYLTPVRDEESESQRKARS-------------------RQARQSRRSTQGVTLTDLQEAEKTIGRSRSTRTREQENEEKDKEEKEKQDKEKQEEKKE----------------------------SEVSREDEYKQKYSRTYDETYARYRPVSTSSSSTPSSSSLSTLG--------SSLYASSQLNRPNSLVGITSAYSRGLTKDNEREGEKKE--EEKEGEDKSQPKSIRERRRPREKRRSTGVSFWTQDSDENEQERQSDTEDGSSKRDTQTDSVSRYD--SSSTSSSDRYDSLLGRSASYSYLEERKPYGSRLEKDDSTDFKKLYEQILAENEKLKAQLHDTNMELTDLKLQLEKATQRQERFADRSLLEMEKRERRALERRISEMEEELKMLPDLKADNQRLKDENGALIRVISKLSK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DBR7-1", "uniprot_id": "MYPT1_MOUSE", "id": "Q9DBR7-1", "name": "Protein phosphatase 1 regulatory subunit 12A", "aln": "-----MKMADAKQKRNEQLKRWIGSETDLEPPVVKRQK-TKVKFDDGAVFLAACSSGDTDEVLKLLHRGADINYANVDGLTALHQACIDDNVDMVKFLVENGANINQPDNEGWIPLHAAASCGYLDIAEFLIGQGAHVGAVNSEGDTPLDIA---EEEAMEELLQNEVNRQGVDIEAARKEEERVMLRDARQWLNSGHISDVR-HAKSGGTALHVAAAKGYTEVLKLLIQAGYDVNIKDYDGWTPLHAAAHWGKEEACRILVDNLCDMETVNKVGQTAFDVADEDILGYLEELQKKQT---------------LLHSEKRD-KKSPLIESTANMENNQPQKAFKNKETLIIEPEKNASRIESLEHEKADEEE------------------------------------------------------------EGKKDESSCSSEEDEEDDSESEAETDKTKP-MASVSNAHTSSTQAAPAAVTAPTLSSNQG---TPTSPVKKFPISTTKISPKEEERKDESPASWRLG----------------------LRKTGSYGALAEISASKEAQKEKDTAGVMRSASSPRLSSSLDNKEKEKDNKGTRLAYVTPTIPRRLASTSDIEEKENRE-SSSLRTSSSYTRRKWEDDLKKN-----------------------SSINEGSTYHRSCS----FGRRQD--DLISCSVPSTTSTPTVTSAAG---------LQRS---------LPSSTSTAAKTPPGSSSAGTQS--------------------------------------STSNRLWAEDSTEKEKDSAPTAVTIPVAPTVVNAAAPSTTTLTTTTAGTVS---EVRERRRSYLTPVRDEESESQRKARS-------------------RQARQSRRSTQGVTLTDLQEAEKTIGRSRSTRTREQENEEKEKEEKEKQDKEKQEEKKE----------------------------SEASREDEYKQKYSRTYDETYTRYRPVSTSSSSAPSSSSLSTLG--------STLYASSQLNRPNSLVGITSAYSRGLAKENEREGEKKE--EEKEGEDKSQPKSIRERRRPREKRRSTGVSFWTQDSDENEQERQSDTEDGSSKRETQTDSVSRYD--SSSTSSSDRYDSLLGRSASYSYLEDRKPYSSRLEKDDSTDFKKLYEQILAENEKLKAQLHDTNMELTDLKLQLEKATQRQERFADRSQLEMEKRERRALERRISEMEEELKMLPDLKADNQRLKDENGALIRVISKLSK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14974-1", "uniprot_id": "MYPT1_HUMAN", "id": "O14974-1", "name": "Protein phosphatase 1 regulatory subunit 12A", "aln": "-----MKMADAKQKRNEQLKRWIGSETDLEPPVVKRQK-TKVKFDDGAVFLAACSSGDTDEVLKLLHRGADINYANVDGLTALHQACIDDNVDMVKFLVENGANINQPDNEGWIPLHAAASCGYLDIAEFLIGQGAHVGAVNSEGDTPLDIA---EEEAMEELLQNEVNRQGVDIEAARKEEERIMLRDARQWLNSGHINDVR-HAKSGGTALHVAAAKGYTEVLKLLIQAGYDVNIKDYDGWTPLHAAAHWGKEEACRILVDNLCDMEMVNKVGQTAFDVADEDILGYLEELQKKQN---------------LLHSEKRD-KKSPLIESTANMDNNQSQKTFKNKETLIIEPEKNASRIESLEQEKVDEEE------------------------------------------------------------EGKKDESSCSSEEDEEDDSESEAETDKTKP-LASVTNANTSSTQAAPVAVTTPTVSSGQA---TPTSPIKKFPTTATKISPKEEERKDESPATWRLG----------------------LRKTGSYGALAEITASKEGQKEKDTAGVTRSASSPRLSSSLDNKEKEKDSKGTRLAYVAPTIPRRLASTSDIEEKENRD-SSSLRTSSSYTRRKWEDDLKKN-----------------------SSVNEGSTYHKSCS----FGRRQD--DLISSSVPSTTSTPTVTSAAG---------LQKS---------LLSSTSTTTKITTGSSSAGTQS--------------------------------------STSNRLWAEDSTEKEKDSVPTAVTIPVAPTVVNAAAS-TTTLTTTTAGTVSSTTEVRERRRSYLTPVRDEESESQRKARS-------------------RQARQSRRSTQGVTLTDLQEAEKTIGRSRSTRTREQENEEKEKEEKEKQDKEKQEEKKE----------------------------SETSREDEYKQKYSRTYDETYQRYRPVSTSSSTTPSSS-LSTMS--------SSLYASSQLNRPNSLVGITSAYSRGITKENEREGEKRE--EEKEGEDKSQPKSIRERRRPREKRRSTGVSFWTQDSDENEQEQQSDTEEGSNKKETQTDSISRYE--TSSTSAGDRYDSLLGRSGSYSYLEERKPYSSRLEKDDSTDFKKLYEQILAENEKLKAQLHDTNMELTDLKLQLEKATQRQERFADRSLLEMEKRERRALERRISEMEEELKMLPDLKADNQRLKDENGALIRVISKLSK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DRG7-1", "uniprot_id": "MYPT1_DANRE", "id": "Q6DRG7-1", "name": "Protein phosphatase 1 regulatory subunit 12A", "aln": "-----MKMADAKQKRNEQLKRWIGSETDLEPPLLKKKK-TKVKFDDGAVFLAACSSGDTEEVLRMLDRGADINYANVDGLTALHQACIDDNVDMVTFLVEHGACINQPDNEGWIPLHAAASCGYLDIAEYLISQGASVGVVNSEGETPLDIA---EEEAMEELLQNEINRQGVDIEAARKEEERIMLRDARQWLNSGQINDVR-HTKSGGTALHVAAAKGYAEVLKLLIQAGYDVNIKDYDGWTPLHAAAHWGKEEACRILVEHLCDMDVVNKVGQTAFDVADEDILGYLEELQKKQN---------------LLLSEKKDVKKSPLIETTTTGDNNQSVKPLKSKETLLLEPEKTAPRIETLEPEKVDEEEG-----------------------------------------------------------EGKKDESSCSSEEEEEEDSESENEADKTKSSVPSSVSNSTPTTAPSSITVTSPTTPSNQVT--TPTSPTKKVSTPAGKLSPKEEDRKDESPASWRLG----------------------LRKTGSYGALAEISTTKEAQKEKDTAGVMRSASSPRLSSSLDNKDKEKEKEKTRLAYVAPTIPRRHVSTSDIDEKENRDSAASLVRSGSYTRRRWEEDLKNSDG--------------------TASTNRTSSYQRSTSHTLALGRTSSSRDLPAKSSSASSLEPNNSKAWQPSSYYQSYSIHRSGSFGRRHEDPLSSTSSSTTTTTTTSSVTSPTGH-----------------------------------RSLLSRYWAEESAEKEKEKEKESAT--VIPTINTAGTTTTTSTTGTVLGSDG-----RERRRSYLTPVRDEESESQRKARS-------------------RQARQSRRSTQGVTLTDLQEAEKTIGRSRPTRPREDE-----KEEKEKQDKEKQEEKKE----------------------------TET-KEDDYRSRY-RSFEEKYRTSLASSTTASSTIPSS-SSSSS--------SSLYSTSSLNRPNSLTGLTSTYSR-STRDTDRESDRKEKDEDRDGDDKSQPRSIRDRRRPREKRRSTGVSFWTQDSDENEPDHPSDSE-GSTKGEPQSDRLSSNDPLSTSTSSTDRYESLSSRGIG----ESRRPYS-RFEKDDSTDYKKLYEQILAENEKLKAQLRDTELELSDLKLQLEKATQRQERFADRSQLEMEKRERRALERKISEMEEELKMLPDLKADNQRLKDENGALIRVISKLSK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9NEB2-1", "uniprot_id": "M9NEB2_DROME", "id": "M9NEB2-1", "name": "Protein phosphatase 1 regulatory subunit 12B", "aln": "MSSLDARNNSAMMKRAEQLKRWEESDTNRAAPTPRHEHGRRIKFSSGCVFLAACLSGDKDEVVQLLDQGADINTANVDGLTALHQACIDDNLDMVEFLVERGADINRQDNEGWTPLHATASCGFVSIARYLVENGADVAAVNSDGDLALDLAIDVQHMAMIDYMEKMVQELNINVDEARKAEELAMLNDAKKWLRSDAAEVDRPHPKTGATALHVAAAKGYTKVLGLLLAGRGNVDRQDNDGWTPLHAASHWGQRETAEMLVESLADMDIRNYAGQSCIDVADRKIVKFLEELRANKRNKRRPSSQIRISDAMENHVEKTPTKLVRVEVRTDATKDAENVKPNQQIHAVEHPVEEEAPWRRKLPRTPSDSPTNNQVPDRELGTNSSETANDVILRRTQSFENDQKFYQKYNELRARIKANSCPILPANANANAAAANKSNNNNNLSSNNYHNNNNNNNKSDLLLGYAAGTTTTTSTPTTTTTTTSSTFNNTHSNTNNTSTTQQQPAAAAAASAANQLYSVQRSASLKDNSMYYRKPTVTIATSTAATAINSPSTTVQTPPIRSQVTAKIAEKSNNGSSSTASVSDAESSKPPPKQSASNMIKNFFKSFVPPVRDEESETQRKAHAKRVRETRRSTQGVTLDEIKSAEELVKKKNMGMANNNNNNNISTTTTNTISNSGNETSSASSTSAPTPSILGSNEQQDELQPPPPPTTPPPAVIPTTTTATDETEIEEVVSSPPAGQSQNDTTASFTLSAPVRRSLSTEGEADANSDPEGDQDQTVVSASYTIMPRRERLPESSENVESIRSPQKTEPVAKSSSEDKSEEPPHARPTDLPLIPAPAAPSTEAIKSSSAATTPAALESPVRLRDKRGLSGSQESETKSDTASPVSSHPDFNARDSLLSLYARRTTDSSAGGGGVGGGAGVGAGGASGAATSSSTSAAERRPSWRLKFDAGSKFKLEDITSGGTYPPNNSTIIPSAPAVMAAANLSTTTGVQRRISSGPIALNASNQSLNSVGRPVSAPSEGTNNSAYVTPSARKFETNATSTGATTAATTTSNSTSNSVSATSANHTTATAPNATSNHDDKDNDKENDNRTQTVIQRRR-KPKRRSTGVVHIDMDELDPERQNESSNNDNEEKEKESGSERTSRSRLGSTASTATTSESKSSSSND------------KTENGDGIDYKALWEAEKLENDKLRQMLKQKDDEAVQTRATLERFAN---ATTKNSLSELEKRERRAMERKLSELEEELKQLDAYKSDNHRLKEENAALIRVISKLSK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .* ** ****** *:*: .* :::: ::**..*.****** ***.:**:::*.:***** *****************:*** ****.** **: ***** ****:****::.**.:*: :** *..***:*: .**:* :. ** : ::: ::. .:::: *** ** **.**::**.*. . * *.*:*.***********::** **: . :*: :* *********:***:.*:..:**: *.**: * .**:.:****..*: :****: :: ** * : * .: : *. :. .:: *: *. ..* *. . ::*. ..: ..:: :.: : :*:. : . *.:: .:. :.*:.: .. . **. :: . .: *. :: . : .*: : . .* . .: . ::* .:*.:: :. *.*... *.. ::. .: : ::*.*. .. : . . *. *: . : *: :*:. :. : *: * . :* .. :* . . .::. . ..: : * :* : :: *. * . . .*:.::*.. . * : ..:. * : . : .: * *. .:***:: .: * *:: :* . ** * : * : .: . * : : : .* * *: .. : .. : :. . *:.:. : *: :. . *: ::: . .** . .*: * : . :. .. ::.: ::..:.::: :*** : ******* . *. : * :. *..: .. * . . . : . :::*: :* . . . : *:.*. *:* *:* **:**: *::.: * : : **: :: :..* *:*******:**::**:***** * *:**:***:**.***********", "identical_positions": 283, "similar_positions": 362, "identity": "21.96%" }, { "cls_id": "homologset.agr.MGI:1309991", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q14525-1", "uniprot_id": "KT33B_HUMAN", "id": "Q14525-1", "name": "Keratin, type I cuticular Ha3-II", "aln": "MPYNFCLPSLSCRTSCSSRPCVPPSCHGYTLPGACNIPANVSNCNWFCEGSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLLCPSYQSYFKTIEELQQKILCSKSENARLVVQIDNAKLAADDFRTKYQTEQSLRQLVESDINSLRRILDELTLCRSDLEAQMESLKEELLSLKQNHEQEVNTLRCQLGDRLNVEVDAAPAVDLNQVLNETRNQYEALVETNRREVEQWFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQAQHNLRYSLENTLTESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQEYQVLLDVRARLECEINTYRSLLESEDCKLPSNPCATTNACEKPIGSCVTN------------PCGPRSRCGPCNTFGY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O76009-1", "uniprot_id": "KT33A_HUMAN", "id": "O76009-1", "name": "Keratin, type I cuticular Ha3-I", "aln": "MSYSCGLPSLSCRTSCSSRPCVPPSCHGCTLPGACNIPANVSNCNWFCEGSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLVCASYQSYFKTIEELQQKILCSKSENARLVVQIDNAKLASDDFRTKYETELSLRQLVESDINGLRRILDELTLCRSDLEAQVESLKEELLCLKQNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNQVLNETRSQYEALVETNRREVEQWFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQAQHNLRDSLENTLTESEARYSSQLSQVQRLITNVESQLAEIRSDLERQNQEYQVLLDVRARLECEINTYRSLLESEDCKLPSNPCATTNACDKSTGPCISN------------PCGLRARCGPCNTFGY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1MAF7-1", "uniprot_id": "F1MAF7_RAT", "id": "F1MAF7-1", "name": "", "aln": "MPYNCCLPALSCRTSCSSRPCVPPSCHGCTLPGACNIPANVGNCNWFCEGSFNGNEKETMQFLNDRLASYLEKVRQLERENAELESRIQERSQQQDPLVCPAYQAYFRTIEELQQKILCSKSENARLVVQIDNAKLAADDFRTKYETELSLRQLVESDINGLRRILDELTLCKSDLEAQVESLKEELLCLKRNHEEEVNTLRCQLGDRLNVEVDAAPTVDLNRVLNETRCQYEALVETNRREVEEWFTTQTEELNKQVVSSSEQLQSCQAEIIELRRTVNALEIELQAQHNLRNSLENTLTESEARYSSQLSQVQCLITNVESQLGEIRADLERQNQEYQVLLDIRARLECEINTYRGLLESEDCKLPCNPCATSNACGKPIGPCVSNPCAPCPPPAPCTPCVPRSRCGPCNSFVR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61897-1", "uniprot_id": "KT33B_MOUSE", "id": "Q61897-1", "name": "Keratin, type I cuticular Ha3-II", "aln": "MPYNCCLPAMSCRTSCSSRPCVPPSCHGCTLPGACNIPANVGNCNWFCEGSFNGNERETMQFLNDRLASYMEKVRQLERENAELECKIQERNQQQDPLVCPAYQAYFRTIEELQQKILCGKSENGRLVVQIDNAKLAADDFRTKYESELSLRQLVESDLNGLRRILDELTLCKSDLEAQVESLRQELLCLKQNHEEEVNTLRCQLGDRLNVEVDAAPTVDLNRVLNETRCQYEALVETNRREVEEWFTTQTEELNKQVVSSSEQLQSCQAEIIELRRTVNALEIELQAQHSMRNSLENTLAESEARYSSQLSQVQCLITNVESQLGEIRADLERQNQEYQVLLDVKARLECEINTYRGLLESEDCKLPCNPCATTNACDKPIGPCVTN------------PCVTRSRCGPCNSFGC", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.*. **::****************** ************.************.*:*************:********:***** *:**.***:**:*.:**:**:***********.****.************:*******::* *********:*.***********:******:***::***.**:***:*********************:****:****** **************:**:******************* **********************.:* ******:************** *********.***:**************::***********.**********.*****:*** *. *.*::* ** *:******:* ", "identical_positions": 337, "similar_positions": 51, "identity": "81.01%" }, { "cls_id": "homologset.agr.MGI:1309992", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B2GV72-1", "uniprot_id": "CRB3_RAT", "id": "B2GV72-1", "name": "Carbonyl reductase [NADPH] 3", "aln": "MSSCSRVALVTGANKGIGFAITRDLCRKFSG-DVVLTARDEARGRAAVKQLQAEGLSPRFHQLDIDNPQSIRALRDFLR--KEYGGLNVLVNNAGIAFRMDDPTPFDVQAEVT-LKTNFFATRNVCTELLPIMKPHGRVVNVSSLQGLKALENCSEDLQERFRCDTLTEGDLVDLMKKFVEDTKNEVHEREGWPDSAYGVSKLGVTVLTRILARQLDEKRKADRILLNACCPGWVKTDMARDQGSRTVEEGAETPVYLALLPPDATEPHGQLVRDKVVQTW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K354-1", "uniprot_id": "CBR3_MOUSE", "id": "Q8K354-1", "name": "Carbonyl reductase [NADPH] 3", "aln": "MSSCSRVALVTGANKGIGFAITRDLCRKFSG-DVVLTARDEARGRAAVQQLQAEGLSPRFHQLDIDDPQSIRALRDFLR--KEYGGLNVLVNNAGIAFRMDDPTPFDIQAEVT-LKTNFFATRNVCTELLPIMKPHGRVVNISSLQGLKALENCREDLQEKFRCDTLTEVDLVDLMKKFVEDTKNEVHEREGWPDSAYGVSKLGVTVLTRILARQLDEKRKADRILLNACCPGWVKTDMARDQGSRTVEEGAETPVYLALLPPDATEPHGQLVRDKVVQTW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75828-1", "uniprot_id": "CBR3_HUMAN", "id": "O75828-1", "name": "Carbonyl reductase [NADPH] 3", "aln": "MSSCSRVALVTGANRGIGLAIARELCRQFSG-DVVLTARDVARGQAAVQQLQAEGLSPRFHQLDIDDLQSIRALRDFLR--KEYGGLNVLVNNAAVAFKSDDPMPFDIKAEMT-LKTNFFATRNMCNELLPIMKPHGRVVNISSLQCLRAFENCSEDLQERFHSETLTEGDLVDLMKKFVEDTKNEVHEREGWPNSPYGVSKLGVTVLSRILARRLDEKRKADRILVNACCPGPVKTDMDGKDSIRTVEEGAETPVYLALLPPDATEPQGQLVHDKVVQNW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W3H4-1", "uniprot_id": "Q9W3H4_DROME", "id": "Q9W3H4-1", "name": "", "aln": "----MNSILITGCNRGLGLGLVKALLNLPQPPQHLFTTCRNREQAKELEDLAKNHSNIHILEIDLRNFDAYDKLVADIEGVTKDQGLNVLFNNAGIAPKSARITAVRSQELLDTLQTNTVVPIMLAKACLPLLKKAAKANESQPMG-----------------VGRAAIINMSSILGSIQGNTDGGMY--------AYRTSKSALNAATKSLSVDLYPQR----IMCVSLHPGWVKTDMGGSSAPLDVPT-STGQIVQTISKLGEKQNGGFVNYDGTPLAW", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *:**.*:*:*:.:.: * . . : ::*: . :::* : . :: ::*: : :: * :. .: *****.***.:* : .. : : *:** ... :.. **::* .:. : ..: : :: .:: .: :*.. :: .* .** .:.. :: *: * :* *: : ** ***** ... * : : :: . .: * : * . *", "identical_positions": 45, "similar_positions": 95, "identity": "16.01%" }, { "cls_id": "homologset.agr.MGI:1309993", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q15323-1", "uniprot_id": "K1H1_HUMAN", "id": "Q15323-1", "name": "Keratin, type I cuticular Ha1", "aln": "MPYNFCLPSLSCRTSCSSRPCVPPSCHSCTLPG-ACNIPANVSNCNWFCEGSFN--GSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLLCPSYQSYFKTIEELQQKILCTKSENARLVVQIDNAKLAADDFRTKYQTELSLRQLVESDINGLRRILDELTLCKSDLEAQVESLKEELLCLKSNHEQEVNTLRCQLGDR-LNVEVDAAPTVDLNRVLNETRSQYEALVETNRREVEQWFTTQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQAQHNLRDSLENTLTESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQEYQVLLDVRARLECEINTYRSLLESEDCNLPSNPCATTNACSKPIGPCLSNPCTSCVPPAPCTPCAPRPRCGPCNSFVR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O76009-1", "uniprot_id": "KT33A_HUMAN", "id": "O76009-1", "name": "Keratin, type I cuticular Ha3-I", "aln": "MSYSCGLPSLSCRTSCSSRPCVPPSCHGCTLPG-ACNIPANVSNCNWFCEGSFN--GSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLVCASYQSYFKTIEELQQKILCSKSENARLVVQIDNAKLASDDFRTKYETELSLRQLVESDINGLRRILDELTLCRSDLEAQVESLKEELLCLKQNHEQEVNTLRCQLGDR-LNVEVDAAPTVDLNQVLNETRSQYEALVETNRREVEQWFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQAQHNLRDSLENTLTESEARYSSQLSQVQRLITNVESQLAEIRSDLERQNQEYQVLLDVRARLECEINTYRSLLESEDCKLPSNPCATTNACDKSTGPCISN------------PCGLRARCGPCNTFGY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1MAF7-1", "uniprot_id": "F1MAF7_RAT", "id": "F1MAF7-1", "name": "", "aln": "MPYNCCLPALSCRTSCSSRPCVPPSCHGCTLPG-ACNIPANVGNCNWFCEGSFN--GNEKETMQFLNDRLASYLEKVRQLERENAELESRIQERSQQQDPLVCPAYQAYFRTIEELQQKILCSKSENARLVVQIDNAKLAADDFRTKYETELSLRQLVESDINGLRRILDELTLCKSDLEAQVESLKEELLCLKRNHEEEVNTLRCQLGDR-LNVEVDAAPTVDLNRVLNETRCQYEALVETNRREVEEWFTTQTEELNKQVVSSSEQLQSCQAEIIELRRTVNALEIELQAQHNLRNSLENTLTESEARYSSQLSQVQCLITNVESQLGEIRADLERQNQEYQVLLDIRARLECEINTYRGLLESEDCKLPCNPCATSNACGKPIGPCVSNPCAPCPPPAPCTPCVPRSRCGPCNSFVR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61765-1", "uniprot_id": "K1H1_MOUSE", "id": "Q61765-1", "name": "Keratin, type I cuticular Ha1", "aln": "MPYNCCLPALSCRTSCSSRPCVPPSCHGCTLPG-ACNIPANVGNCNWFCEGSFN--GNEKETMQFLNDRLASYMEKVRQLERENAELECRIQERNQQQDPLVCPAYQAYFRTIEELQQKILCSKSENARLVVQIDNAKLAADDFRTKYETELGLRQLVESDINGLRRILDELTLCKSDLEAQVESLKEELLCLKRNHEEEVNTLRCQLGDR-LNVEVDAAPTVDLNRVLNETRCQYEAMVETNRREVEEWFTTQTEELNKQVVSSSEQLQSCQAEIIELRRTVNALEIELQAQHCMRNSLENTLTESEARYSSQLSQVQCLITNVESQLGEIRADLERQNQEYQVLLDVKARLECEINTYRGLLESEDCKLPCNPCATSNACGKPIGPCVSNPCVPCPPPAPCTPCVPRPRCGPCNSFVR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8N7TEZ1-1", "uniprot_id": "A0A8N7TEZ1_DANRE", "id": "A0A8N7TEZ1-1", "name": "", "aln": "-MQSFSANKRTYRMSSEDLGGLRPTFYSWRSAGNRGSFSKDIFGSTNVQTGVVGNVGNEKVTMQILNERLASYLEKVRILEKANGDLEVKIRQVMEKKGPDTT-DYSHFQVTLDKLRKEILEMIMRNVNVNLQIDNAKLAAEDFKIKFENEFQQRQCVEADINALRKMLDDTNVARLHLENDVEGLKVELIEIKKQHQLELSALNGQITQSGVQVDINAPKGQDLAKIMEEMRANYEKIVLKNQEELKAWHESKISVVQVQVTENTAALKEASTQLSVSRRRMQTLETDLQTLTGSRASLEEALNETKLRYGMQVEQFNNIILLRESELKQLRDDIQRQSLDYQVLFNIKMELEAEIATYKRLLDGEETLQ--NRSVSETVTRTTMETKILS----------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : * *... : *: :. .* .:. :: ... . * .. *.** ***:**:*****:**** **: *.:** *:: ::: * *. : *:::*:::** .*..: :********::**: *::.*: ** **:***.**::**: .:.: .** :**.** **: :* :*: *:.:*. *: : ::*:::*. ** ::::* *.:** :* .*:.*:: *. :: . :: **...: *:. .::: ** :::** :**: * ***::*.*:: **. *:.*.: :* **:* ::* *::**. :****:::: .**.** **: **:.*: * ..: .. .. . : . ", "identical_positions": 124, "similar_positions": 152, "identity": "29.52%" }, { "cls_id": "homologset.agr.MGI:1309994", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A0G6-1", "uniprot_id": "A0A8I6A0G6_RAT", "id": "A0A8I6A0G6-1", "name": "", "aln": "MPYNCCLPALSCRTSCSSRPCVPPSCHGCTLPGACNIPANVGNCNWFCEG-------------SFNGNEKETMQFLNDRLASYLEKVRQLERENAELESRIQERSQQQDPLVCPAYQAYFRTIEELQQKILCGKSENARLVVQIDNAKLASDDFRTKYETELSLRQLVESDINGLRRILDELTLCKSDLEAQVESLKEELLCLKQNHEQEVNTLRCQLGDR-LNVEVDAAPTVDLNRVLNETRCQYEALVETNRREVEEWFTTQTEELNKQVVSSSEQLQSCQAEIIELRRTVNALEIELQAQHNLRNSLENTLTESEARYSSQLSQVQCLITNVESQLGEIRADLERQNQEYQVLLDIRARLECEINTYRGLLESEDCNLPCNPCATTNACDKPIGPCVSN------------PCVTRPRCGPCNTFVR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F1MAF7-1", "uniprot_id": "F1MAF7_RAT", "id": "F1MAF7-1", "name": "", "aln": "MPYNCCLPALSCRTSCSSRPCVPPSCHGCTLPGACNIPANVGNCNWFCEG-------------SFNGNEKETMQFLNDRLASYLEKVRQLERENAELESRIQERSQQQDPLVCPAYQAYFRTIEELQQKILCSKSENARLVVQIDNAKLAADDFRTKYETELSLRQLVESDINGLRRILDELTLCKSDLEAQVESLKEELLCLKRNHEEEVNTLRCQLGDR-LNVEVDAAPTVDLNRVLNETRCQYEALVETNRREVEEWFTTQTEELNKQVVSSSEQLQSCQAEIIELRRTVNALEIELQAQHNLRNSLENTLTESEARYSSQLSQVQCLITNVESQLGEIRADLERQNQEYQVLLDIRARLECEINTYRGLLESEDCKLPCNPCATSNACGKPIGPCVSNPCAPCPPPAPCTPCVPRSRCGPCNSFVR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D646-1", "uniprot_id": "KRT34_MOUSE", "id": "Q9D646-1", "name": "Keratin, type I cuticular Ha4", "aln": "MSCESCLPALSCRTSCSSRPCVPPSCHGCTLPGACNIPANVGNCNWFCEG-------------SFNGNEKETMQFLNDRLASYMEKVRQLERENAELECRIQERNQQQDPLVCPAYQAYFRTIEELQQKILCAKSENARLVVQIDNAKLASDDFRTKYQTELSMRQLVEADINSLRRILDELTLCKSDLEAQVESLREELLCLKKNHEEEVNTLRCQLGDR-LNVEVDAAPTVDLNRVLNETRCQYEALVETNRREVEEWFTTQSEELNKQVVSSSEQLQSCQAEIIELRRTVNALEIELQAQHCMRNSLENTLTESEARYSSQLSQVQCLITNVESQLGEIRADLERQNQEYQVLLDVRARLECEINTYRSLLESEDCNLPCNPCATTNASGSCCGPCGSS-----------------KRCC-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14525-1", "uniprot_id": "KT33B_HUMAN", "id": "Q14525-1", "name": "Keratin, type I cuticular Ha3-II", "aln": "MPYNFCLPSLSCRTSCSSRPCVPPSCHGYTLPGACNIPANVSNCNWFCEG-------------SFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLLCPSYQSYFKTIEELQQKILCSKSENARLVVQIDNAKLAADDFRTKYQTEQSLRQLVESDINSLRRILDELTLCRSDLEAQMESLKEELLSLKQNHEQEVNTLRCQLGDR-LNVEVDAAPAVDLNQVLNETRNQYEALVETNRREVEQWFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQAQHNLRYSLENTLTESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQEYQVLLDVRARLECEINTYRSLLESEDCKLPSNPCATTNACEKPIGSCVTN------------PCGPRSRCGPCNTFGY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q15323-1", "uniprot_id": "K1H1_HUMAN", "id": "Q15323-1", "name": "Keratin, type I cuticular Ha1", "aln": "MPYNFCLPSLSCRTSCSSRPCVPPSCHSCTLPGACNIPANVSNCNWFCEG-------------SFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLLCPSYQSYFKTIEELQQKILCTKSENARLVVQIDNAKLAADDFRTKYQTELSLRQLVESDINGLRRILDELTLCKSDLEAQVESLKEELLCLKSNHEQEVNTLRCQLGDR-LNVEVDAAPTVDLNRVLNETRSQYEALVETNRREVEQWFTTQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQAQHNLRDSLENTLTESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQEYQVLLDVRARLECEINTYRSLLESEDCNLPSNPCATTNACSKPIGPCLSNPCTSCVPPAPCTPCAPRPRCGPCNSFVR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O76009-1", "uniprot_id": "KT33A_HUMAN", "id": "O76009-1", "name": "Keratin, type I cuticular Ha3-I", "aln": "MSYSCGLPSLSCRTSCSSRPCVPPSCHGCTLPGACNIPANVSNCNWFCEG-------------SFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLVCASYQSYFKTIEELQQKILCSKSENARLVVQIDNAKLASDDFRTKYETELSLRQLVESDINGLRRILDELTLCRSDLEAQVESLKEELLCLKQNHEQEVNTLRCQLGDR-LNVEVDAAPTVDLNQVLNETRSQYEALVETNRREVEQWFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQAQHNLRDSLENTLTESEARYSSQLSQVQRLITNVESQLAEIRSDLERQNQEYQVLLDVRARLECEINTYRSLLESEDCKLPSNPCATTNACDKSTGPCISN------------PCGLRARCGPCNTFGY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O76011-1", "uniprot_id": "KRT34_HUMAN", "id": "O76011-1", "name": "Keratin, type I cuticular Ha4", "aln": "MSYSCCLPSLGCRTSCSSRPCVPPSCHGYTLPGACNIPANVSNCNWFCEG-------------SFNGSEKETMQFLNDRLASYLEKVRQLERDNAELEKLIQERSQQQEPLLCPSYQSYFKTIEELQQKILCAKAENARLVVNIDNAKLASDDFRSKYQTEQSLRLLVESDINSIRRILDELTLCKSDLESQVESLREELICLKKNHEEEVNTLRSQLGDR-LNVEVDTAPTVDLNQVLNETRSQYEALVEINRREVEQWFATQTEELNKQVVSSSEQLQSCQAEIIELRRTVNALEIELQAQHNLRDSLENTLTESEAHYSSQLSQVQSLITNVESQLAEIRCDLERQNQEYQVLLDVRARLECEINTYRSLLESEDCKLPCNPCATTNASGNSCGPCGTS------------------QKGCCN----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B8A615-1", "uniprot_id": "B8A615_DANRE", "id": "B8A615-1", "name": "", "aln": "MSFDPFTTSSLSRRWEDFQSSTSTYRISRGPLSSSRWAMRLEPLQRWDQSDLSQASLVNAELLDLRAQEREQLVGLNNRFASYIEKVRHLEQQNRALLLQLEALRRRQ-SQPSRVQQLYLQEVRGLREQLHQEAQNKARMEVQMEKLRDVHAQLHERWEEEARRRSQAEEDLQQLRDETGQAALCICDAEASVVSLVQELAFLKQVFAEEQEGLRVQLQVASLSVELDTS-RPDLSAALREIRAQYESLAGRNMQTAEAWFRGKVASVVELTDKQEEAVRVVREETAEYRRMLQSRSAEVEALRNVINSLNIQLGELEEMQNSEVTKYQGKIGDLERDIGDAKEEMSRYLREYQDLLNVKMALDVEIAAYRKLLEGEEIRFTYSSLPALA----------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. . .: .* . :..... . .:.. . .: : : :. .:...*:* : **:*:***:****:**::* * :. ::* . . * *:: :. *:::: ::**: *:::: : . ::: ::: * * .* *:: :* .: :** .* *:.: ** :** ** . :* : ** ** *.**:*:: **. .*.* * ***:*. * : .* ** : .: : . ...* :: : * * ** ::: . *::* : : **: * * * .*:::: * * ::* ::.: : ::.* :*** **::: *: ** :** ***.*: .:. .. .: ", "identical_positions": 93, "similar_positions": 142, "identity": "21.63%" }, { "cls_id": "homologset.agr.MGI:1309995", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1MAS0-1", "uniprot_id": "F1MAS0_RAT", "id": "F1MAS0-1", "name": "", "aln": "MPSSCCITNTSSASLKSSARPSSVCSSNMGSRSELCLGYVCQPLQCMPSICMPTTYRPASCLSKTYLSSSCQPSNRRPTGCISSSMGTYGLFCEGAFNGNEKETMQVLNDRLANYLEKVRQLEKENAELEGKIQDVYQAQVLTMCPDYQSYFQTIEELQQKVLCTKAENARMIVHIDNAKLAADDFRTKYETELALRQLVEADTNGLRRILDELTLNKADLEAQVESLKEELLCLKRNHEEEVGVLRQQLGDRLNIEVDAAPPVDLTRMLEEMRCQYETMVQTNHRDVEEWFNMQMEELNKQVATSSEQLQSYQSDIIDLRRTVNTLEIELQAQHSLRDSLENTLGETEGRFTSQLSQMQCMITNVESQLADIRCDLERQNQEYKVLLDVKARLECEIDTYRGLLESEDSNLPS-PCSNFLSNISSCFFCYSESYPTKASVVNSHACQGQAVTIHM--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q62168-1", "uniprot_id": "K1H2_MOUSE", "id": "Q62168-1", "name": "Keratin, type I cuticular Ha2", "aln": "----------------------------------------------MPSVCMPTTYRPASCLSKTYLSSSCQPSNRRPTGCISSSMGTYGLFCEGAFNGNEKETMQVLNDRLANYLEKVRQLEKENAELEGKIQDVYQGQVLTMCPDYQSYFQTIEELQQKVLCTKAENARMIVHIDNAKLAADDFRTKYETELALRQLVEADTNGLRRILDELTLNKADLEAQVESLKEELLCLKRNHEEEVGVLRQQLGDRLNIEVDAAPPVDLTRMLEEMRCQYETMVETNHRDVEEWFNMQMEELNKQVATSSEQLQSYQSDIIDLRRTVNTLEIELQAQHSLRDSLENTLGETEGRFTSQLSQMQCMITNVESQLSDIRCDLERQNQEYKVLLDVKARLECEIDTYRGLLESEDSKLPCNPCS-----TPSCQPCAPSPGVSRTVCVPHTVCVPCSPCLQTRY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14532-1", "uniprot_id": "K1H2_HUMAN", "id": "Q14532-1", "name": "Keratin, type I cuticular Ha2", "aln": "MTSSCCVTNNLQASLKSCPRPASVCSSGVNCRPELCLGYVCQPMACLPSVCLPTTFRPASCLSKTYLSSSCQAASG-----ISGSMGPGSWYSEGAFNGNEKETMQFLNDRLASYLTRVRQLEQENAELESRIQEASHSQVLTMTPDYQSHFRTIEELQQKILCTKAENARMVVNIDNAKLAADDFRAKYEAELAMRQLVEADINGLRRILDDLTLCKADLEAQVESLKEELMCLKKNHEEEVGSLRCQLGDRLNIEVDAAPPVDLTRVLEEMRCQYEAMVEANRRDVEEWFNMQMEELNQQVATSSEQLQNYQSDIIDLRRTVNTLEIELQAQHSLRDSLENTLTESEARYSSQLAQMQCMITNVEAQLAEIRADLERQNQEYQVLLDVRARLEGEINTYRSLLENEDCKLPCNPCS-----TPSCTTCVPSPCVPRTVCVPRTVGMPCSPCPQGRY", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :**:*:***:****************.:. **.***. . :.*************.******.** :*****:******.:**:. :.***** *****:*:********:**********:*:************:***:***:******* ********:*** ***************:***:******* ** ********************:*********:**::*:***************:**********.********************************* *:*.*::***:**********:**::**.*********:*****:**** **:***.***.**.:**. *** .** * ... .:: * . : : ", "identical_positions": 301, "similar_positions": 67, "identity": "65.72%" }, { "cls_id": "homologset.agr.MGI:1309997", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9BYQ3-1", "uniprot_id": "KRA93_HUMAN", "id": "Q9BYQ3-1", "name": "Keratin-associated protein 9-3", "aln": "MT-HCCSPCCQPTCCR-----TTCWQPTTVTTCSSTPCCQPSCCVSSCCQPCCHPTCCQNTCCRTTCCQPICVTSCCQPSCCS----------TPCCQPTCCGSSCG----------QSSSCAPVYCRRTCYHPTSVCLPGCLNQSCGSNCCQP-----CCRPACCETTCCRTTCFQPT-----------CVYSCCQPSCC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A8MTY7-1", "uniprot_id": "KRA97_HUMAN", "id": "A8MTY7-1", "name": "Keratin-associated protein 9-7", "aln": "MT-HCCSPCCQPTCCR-----TTCWKPTTVTTCSSTPCCQPSCCVSSCCQPCCHPTCCQNTCCRTTCCQPTCVTSCCQPSCCS----------TPCCQPICCGSSCCGQTSCGSSCCQPSSCAPIYCRRTCYHPTSVYLPGCLNQSCGSSCCQP-----CCRPACCETTCCRTTCFQPT-----------CVTSCCQPACC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9BYQ0-1", "uniprot_id": "KRA98_HUMAN", "id": "Q9BYQ0-1", "name": "Keratin-associated protein 9-8", "aln": "MT-HCCSPCCQPTCCR-----TTCWKPTTVTTCSSTPCCQPSCCVSSCCQPCCRPTCCQN-----TCCQPICVTSCCQPSCCS----------TPCCQPTCCGQTSCG-----SSCGQSSSCAPVYCRRTCYHPTTVCLPGCLNQSCGSNCCQP-----CCRPACCETTCCRTTCFQPT-----------CVSSCCQPSCC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9BYQ4-1", "uniprot_id": "KRA92_HUMAN", "id": "Q9BYQ4-1", "name": "Keratin-associated protein 9-2", "aln": "MT-HCCSPCCQPTCCRTTCCRTTCWKPTTVTTCSSTPCCQPACCVSSCCQPCCRPTCCQNTCCRTTCCQPTCVTSCCQPSCCSTPCCQPTCCGSSCCGQTSCGSSCG----------QSSSCAPVYCRRTCYYPTTVCLPGCLNQSCGSNCCQP-----CCRPACCETTCCRTTCFQPT-----------CVSSCCQPSCC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9BYP9-1", "uniprot_id": "KRA99_HUMAN", "id": "Q9BYP9-1", "name": "Keratin-associated protein 9-9", "aln": "MT-HCCSPCCQPTCCRTTCCRTTCWKPTTVTTCSSTPCCQPSCCVSSCCQPCCRPACCQNTCCRTTCCQPTCLS--------------------SCCGQTSCGSSCG----------QSSSCAPVYCRRTCYYPTTVCLPGCLNQSCGSSCCQP-----CCRPACCETTCCRTTCFQPT-----------CVSSCCQPSCC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9BYQ2-1", "uniprot_id": "KRA94_HUMAN", "id": "Q9BYQ2-1", "name": "Keratin-associated protein 9-4", "aln": "MT-HCCSPCCQPTCCRTTCCRTTCWKPTTVTTCSSTPCCQPSCCVSSCCQPCCRPTCCQN-----TCCQPTCVTSCCQPSCCS----------TPCCQPTCCGSSCD----------QSSSCAPVYCRRTCYYPTTVCLPGCLNQSCGSNCCQP-----CCRPACCET-----TCFQPT-----------CVSSCCQPFCC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A8MVA2-1", "uniprot_id": "KRA96_HUMAN", "id": "A8MVA2-1", "name": "Keratin-associated protein 9-6", "aln": "MT-HCCSPGCQPTCCRTTCCRTTCWQPTIVTTCSSTPCCQPSCCVSSCCQPYCHPTCCQNTCCRTTCCQPTCVTSCCQPSCCS----------TPCYQPICCGSSCCGQTSCGSSCGQSSSCAPVYCRRTCYHPTTVCLPGCLNQSCGSSCCQP-----CYCPACCVS-------------------------SCCQHSCC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0LG94-1", "uniprot_id": "A0ABK0LG94_RAT", "id": "A0ABK0LG94-1", "name": "", "aln": "MTNSCCSPCCQPTCCRTTCCRTTCWKPSCVTSCC-QPCCQPSCCGSSCCQPCCQTTCCRT-CFQPSCVSSCCSTPCCQPCCCVSS------CCQPCCRPSCCQP-CCRPS-----CCESSCCQPRCCISSCCQP--CCRPSCCQSSCCKPCCQPFCLNLCCEPACSGPVTCTRTCYQPTSVCVPGCLSQGCGSSCSQSC-C", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3ZAY4-1", "uniprot_id": "D3ZAY4_RAT", "id": "D3ZAY4-1", "name": "", "aln": "MTNSCCSSCCQPTCCRTTCCRTTCWKPSCVTSCC-QPCCQPSCCGSSCCQPCCQTTCCRT-CFQPSCVSSCCSTPCCQPCCCVSS------CCQPCCRPSCCQSSCCQPC-----CCESSCCQPRCCISSCCQP--CCKPSCCQSSCCKPCCKPFCLNLCCEPACSGPVTCTRTCYQPTSVCVPGCLSQGCGSSCCEPCGC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q64526-1", "uniprot_id": "Q64526_MOUSE", "id": "Q64526-1", "name": "", "aln": "MTNSCCSPCCQPTCCRTTCCRTTCWRPSCVTSCC-QPCCQPSCCGSSCCQPCCQTTCCRT-CFQPCCVSSCCRTPCCQPCCCVSS------CCQPCCQPSCCQSSCCQPR-----CCESSCCQPRCCISSCCQP--CCRPSCCQSSCCRPCCQPFCLNLCCQPACSGPVTCTRTCYQPTCVCVPGCLSQGCGSSCCEPCGC", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** ***. ******* ****:*: **:*. *****:** ****** *:.:**:. * .. * : .* .* . :.*.* * * :* * *.* :.** **:* * ***. . **.: *", "identical_positions": 60, "similar_positions": 29, "identity": "29.85%" }, { "cls_id": "homologset.agr.MGI:1309998", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0R9F7-1", "uniprot_id": "M0R9F7_RAT", "id": "M0R9F7-1", "name": "", "aln": "--MGSKETLKEEAFLGSTEDGADFDQDMLPVMET-FEINDPVPKKRNGRTLCMAVMAIHLILLTAGTALLLIQVLNLQEQFQSLEMCCDNGTLAAEDKPFFS--LQWARPKTHIVSGAQGLQALQAQLSWVHTSQEQLRQQVDNLTQNPELFRIKGERGSP---GPKGAPGAPGIPGLPGPSAAKGEKGAAGRDGTPGVRGPQGPPGTKGEAGLQGFTGAPGKQGADGAPGPQGEKGSKGDKGLTGPKGEHGTKGDKGDLGLPGSKGDTGMKGDRGVTGSPGAQGNKGDAGKPGLPGLAGSPGAKGDQGKLGVQGPPGPPGAPGQSGAKGEPGRTGPPGPTGPPGIAGNPGAAGLKGSKGDIGIQ------GQKGTKGES--GVPGLVGRKGDTGSPGLAGPKGEPGRAGLKGEPGMKGSSGQQGQKGEKGQKGDF-----NLVVRIVGGTSRGRAEVYYNNVWGTICDDGWDNNDATVFCRMLGYSSGRGLGSFGGGTGKIWLDDVSCLGTEATLWDCRKSSWGSHNCNHNEDAGVECR-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60754-1", "uniprot_id": "MARCO_MOUSE", "id": "Q60754-1", "name": "Macrophage receptor MARCO", "aln": "--MGSKELLKEEDFLGSTEDRADFDQAMFPVMET-FEINDPVPKKRNGGTFCMAVMAIHLILLTAGTALLLIQVLNLQEQLQMLEMCCGNGSLAIEDKPFFS--LQWA-PKTHLVPRAQGLQALQAQLSWVHTSQEQLRQQFNNLTQNPELFQIKGERGSP---GPKGAPGAPGIPGLPGPAAEKGEKGAAGRDGTPGVQGPQGPPGSKGEAGLQGLTGAPGKQGATGAPGPRGEKGSKGDIGLTGPKGEHGTKGDKGDLGLPGNKGDMGMKGDTGPMGSPGAQGGKGDAGKPGLPGLAGSPGVKGDQGKPGVQGVPGPQGAPGLSGAKGEPGRTGLPGPAGPPGIAGNPGIAGVKGSKGDTGIQ------GQKGTKGES--GVPGLVGRKGDTGSPGLAGPKGEPGRVGQKGDPGMKGSSGQQGQKGEKGQKGES-----FQRVRIMGGTNRGRAEVYYNNEWGTICDDDWDNNDATVFCRMLGYSRGRALSSYGGGSGNIWLDNVNCRGTENSLWDCSKNSWGNHNCVHNEDAGVECS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UEW3-1", "uniprot_id": "MARCO_HUMAN", "id": "Q9UEW3-1", "name": "Macrophage receptor MARCO", "aln": "--MRNKKILKEDELLSETQQ-AAFHQ---IAMEP-FEINVPKPKRRNGVNFSLAVVVIYLILLTAGAGLLVVQVLNLQARLRVLEMYFLNDTLAAEDSPSFSL-LQSAHPGEHLAQGASRLQVLQAQLTWVRVSHEHLLQRVDNFTQNPGMFRIKGEQGAPGLQGHKGAMGMPGAPGPPGPPAEKGAKGAMGRDGATGPSGPQGPPGVKGEAGLQGPQGAPGKQGATGTPGPQGEKGSKGDGGLIGPKGETGTKGEKGDLGLPGSKGDRGMKGDAGVMGPPGAQGSKGDFGRPGPPGLAGFPGAKGDQGQPGLQGVPGPPGAVGHPGAKGEPGSAGSPGRAGLPGSPGSPGATGLKGSKGDTGLQ------GQQGRKGES--GVPGPAGVKGEQGSPGLAGPKGAPGQAGQKGDQGVKGSSGEQGVKGEKGERGEN-----SVSVRIVGSSNRGRAEVYYSGTWGTICDDEWQNSDAIVFCRMLGYSKGRALYKVGAGTGQIWLDNVQCRGTESTLWSCTKNSWGHHDCSHEEDAGVECSV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BH24-1", "uniprot_id": "A0A8M2BH24_DANRE", "id": "A0A8M2BH24-1", "name": "", "aln": "METEVDDFPGKASIFSQVNPLYSNNMKLCEAERYDFQHSEPKTMKSASKRHCVPVLILLFLLLIGLNSFLAYKVFTLEAWVHTHCTSAQNHELTSASSFQLGSSKNEVECFTDLCGTDGTLEHLRTQINQLNATAEKAIVCPPGPPGPPGSNGIPGFPGQK---GIPGSPGRVGEPGAPGQKGQTGDPGIKGERGMVGFPGIPGAPGRKGDSGERGLQGLPGNDGSPGQDGRTGPQGMPGPSGSQGVKGDPGLKGERGDQGPPGPTGPQGSSGARGLQGIPGEKGSPGPKGDTG-VGLQGPTGQQGQKGSQGVPGVPGARGANGEKGDRGLSGVKGDPGLKGERGDQGQPGPTGPQGSSGARGLQGIPGGKGSPGPKGDTGVGLRGLTGQQGQKGSQGLPGVPGARGANGEKGDRGLSGQKGDQGPKGEKGDAGAKGASGGSQVVRLVGSSTRGRVEVFYQNVWGTVCDDSFDNLDALVVCRMLGFQRSTQVYTDGSGSGRIWLDELRCTGTESSIFNCPHAGMGINNCGHGEDVGVSCA-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. : ::...: . . . *: . * . : . .:.*: : ::** . .:* :*:.*: .: * *: .. :. : . .: *: *::*:. :..: *: . . * * * * * *: * * ** ** . .* * *. * * * *.** **::* :* * **::*: * * * :* * * * **: * **::** * ** .* * .* * * ** :*. * * .* ** * .* :*::*. *: * **. ** * * :* .* * ** * * *.** :* :**.* *:* *. * **:: *: * .* :*: ** **.* * * * **: *:.*..*:** *****: * **::*.:.***.**:*.. ***:*** ::* ** *.*****:. . : . *.*:*.****:: * *** :::.* : . * ::* * **.**.* ", "identical_positions": 174, "similar_positions": 136, "identity": "32.16%" }, { "cls_id": "homologset.agr.MGI:1309999", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K247-1", "uniprot_id": "A0A0G2K247_RAT", "id": "A0A0G2K247-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------MEPPACAEAAVKDPAARDHDPVDAKIS--APAADPLPRTSS-QKEGHS------------------------------------------------------------------------LQDWDTIATVGTGTFGRVNLVKEKTGRRYCALKIMSIPDVIRLKQEQHVQNEKAVLKEINHPFLIKLLWTDHDNRFLYMLMEFVPGGELFTYLRNRGRFSSVAAIFYATEIVCAIEYLHSKEIVYRDLKPENILLDREGHIKLTDFGFAKKLVDRTWTLCGTPEYLAPEVIQSKGHGRAVDWWALGILIFEMLSGFPPFFDDNPFGIYQKILACKIDFPRQLDFTSKDLIKKLLVVDRTRRLGNMKCVCFLSRMGQKTSSGTGGSEVWSGSPCHRGNLSHPLCPSYPVMVTSPTLRLIQRVSWTRLLLYLMKIWKHSKISEDENSCLQEVCEDIHTTLMTRTVLLLYPFLAVKLEGLVCVCGCVYASSCNVNTIHHPWDPASFQQLETCPVKISQKLLNCRFSPSS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q922R0-1", "uniprot_id": "PRKX_MOUSE", "id": "Q922R0-1", "name": "cAMP-dependent protein kinase catalytic subunit PRKX", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------MEPPAGAAATVKDP---DHDPVKTKVS--APAADPKPRTSS-QKAGHS------------------------------------------------------------------------LQDWDTIATVGTGTFGRVNLVKEKTGRQYCALKIMSIPDVIRLKQEQHVQNEKAVLKEINHPFLIKLLWTGHDNRFLYMLMEFVPGGELFTYLRNRGRFSSVASVFYATEIVCAIEYLHSKEIVYRDLKPENILLDREGHIKLTDFGFAKKLVDRTWTLCGTPEYLAPEVIQSKGHGRAVDWWALGILIFEMLSGFPPFFDDNPFGIYQKILACKIDFPRQLDFTSKDLIKKLLVVDRTRRLGNMK----------------NGAEDIKRHRWFRG------------------------VEWESVPQRKLKPPIVPKLSGDG---------DISN---------FETYPESELDKTPSVS---------------DKDLETFKNF--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P51817-1", "uniprot_id": "PRKX_HUMAN", "id": "P51817-1", "name": "cAMP-dependent protein kinase catalytic subunit PRKX", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------MEAPGLAQAAAAES---DSRKVAEETPDGAPALCPSPEALSPEPPVYS------------------------------------------------------------------------LQDFDTLATVGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRLKQEQHVHNEKSVLKEVSHPFLIRLFWTWHDERFLYMLMEYVPGGELFSYLRNRGRFSSTTGLFYSAEIICAIEYLHSKEIVYRDLKPENILLDRDGHIKLTDFGFAKKLVDRTWTLCGTPEYLAPEVIQSKGHGRAVDWWALGILIFEMLSGFPPFFDDNPFGIYQKILAGKIDFPRHLDFHVKDLIKKLLVVDRTRRLGNMK----------------NGANDVKHHRWFRS------------------------VDWEAVPQRKLKPPIVPKIAGDG---------DTSN---------FETYPENDWDTAAPVP---------------QKDLEIFKNF--------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QN39-1", "uniprot_id": "F1QN39_DANRE", "id": "F1QN39-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------MASTKGKAGINNES---SSGRDSGRTEAGSPTLPAGAASLT-TNRTYT------------------------------------------------------------------------LDDLDTIATVGTGTFGRVFLVKDKKTRGFFALKAMKIPDVIRLKQEQHVHNEKEVLTEVNHPFLVRLFWTHHDDRFLYMLMEYVNGGELFSYLRSRGHFSNSTGMFYSAEIVCAIEYLHSKEIVYRDLKPENILLDSEGHIRLTDFGFAKKLSERTWTLCGTPEYLAPEVIQSKGHGRAVDWWALGVLIFEMLAGYPPFFDDNPFGIYQKILAGKLEFPRHLDLYVKDLIKKFLVTDRERRLGNMK----------------NGADDVKKHRWFKS------------------------VNWESVPCRKLKPPIVPKVSHEG---------DTSN---------FDSYPDEEWKKDTPVP---------------AKDLEIFKNF--------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P16912-1", "uniprot_id": "KAPC3_DROME", "id": "P16912-1", "name": "cAMP-dependent protein kinase catalytic subunit 3", "aln": "MDLWHIFLERILVACRVSASVFANFGCGLYSSWKLICGDHDSASGLRAGLATPTQRGKATGDNGTTGTPARTIGKPQARIATAMSTATCARFCTPLSSGTAGSTSKLTTGNGSGNTMTSAYKIPSNNSTTANDSSNTETTFTFKLGRSNGRSSSNVASSESSDPLESDYSEEDPEQEQQRPDPATNSRSSSTATTTTTSSADHDNDVDEEDEEDDENEGEGNGRDADDATHDSSESIEEDDGNETDDEEDDDESEESSSVQTAKGVRKYHLDDYQIIKTVGTGTFGRVCLCRDRISEKYCAMKILAMTEVIRLKQIEHVKNERNILREIRHPFVISLEWSTKDDSNLYMIFDYVCGGELFTYLRNAGKFTSQTSNFYAAEIVSALEYLHSLQIVYRDLKPENLLINRDGHLKITDFGFAKKLRDRTWTLCGTPEYIAPEIIQSKGHNKAVDWWALGVLIYEMLVGYPPFYDEQPFGIYEKILSGKIEWERHMDPIAKDLIKKLLVNDRTKRLGNMK----------------NGADDVKRHRWFKH------------------------LNWNDVYSKKLKPPILPDVHHDG---------DTKN---------FDDYPEKDWKPAKAVD---------------QRDLQYFNDF--------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. . :. . . * . . : : : *:* : : ********** * ::: . : *:* : :.:****** :**:**: :* *: ***:: * *: :*: ***::::* *****:***. *:*:. :. **::**:.*:***** :**********:*:: :**:::********* :***********:***:******.:********:**:*** *:***:*::*****:***: *::: *::* ******:** ** :****** .*:: . .: :.* : :* ..: : * . : : . . * * *::: ", "identical_positions": 152, "similar_positions": 101, "identity": "22.49%" }, { "cls_id": "homologset.agr.MGI:1310000", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q91ZF1-1", "uniprot_id": "KCJ15_RAT", "id": "Q91ZF1-1", "name": "ATP-sensitive inward rectifier potassium channel 15", "aln": "-----------------------------------------------------------MVARWVKGSEDAPLALQKIPDLQSGPRSLRMEAIHIGMSSAPLVKHSNGVGLKAHRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFGVVYYAIAFIHGDLELGESNSNHT-----PCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVISKQNGKLCLVIQVANMRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLDETSPLRDLTPQNLK-EKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLS-KNGKYVADFSQFEQIRKSPDCTFYCADSEKQKLEEQYRQEDQRERELRSLLLQQSNV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88932-1", "uniprot_id": "KCJ15_MOUSE", "id": "O88932-1", "name": "ATP-sensitive inward rectifier potassium channel 15", "aln": "-----------------------------------------------------------------------------------------MDAIHLGMSSAPLVKHTNGVGLKAHRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFGVVYYAIAFIHGDLQLGESNSNHT-----PCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVISKQNGKLCLVIQVANMRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLDETSPLRDLTPQNLK-EKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLS-KNGKYVADFSQFEQIRKSPDCTFYCADSEKQKLEEQYRQEDQRERELRSLLLQQSNV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99712-1", "uniprot_id": "KCJ15_HUMAN", "id": "Q99712-1", "name": "ATP-sensitive inward rectifier potassium channel 15", "aln": "-----------------------------------------------------------------------------------------MDAIHIGMSSTPLVKHTAGAGLKANRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFGVIYYAIAFIHGDLEPGEPISNHT-----PCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANMRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLDETSPLRDLTPQNLK-EKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLS-KNGKYVADFSQFEQIRKSPDCTFYCADSEKQQLEEKYRQEDQRERELRTLLLQQSNV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QQH0-1", "uniprot_id": "F1QQH0_DANRE", "id": "F1QQH0-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------MTNTVRRLVSKDGRSNVKIDNVEGMVKLFLHDLWTTVVDMKWRYKITLFASTFVMTWFVFGVLFYLIGLRNGDFH-ADPSSNHT-----PCVMNVHTLTGAYLFSLETQTTIGYGFRHVSEECPLAIGALVLQLVLTGLAEIFVTGAFLAKLARPKKRAGTIKFSRCAVVCRRGGRWCLMVRVANMRSSLLIQCQLSGKLLAPHVTLEGQKTLVHQTTVDFQMDSSGECPFLLLPLTFYHVLDERSPLADLTAHSLQ-KRDFELLLTLNATVESTAASCQSRTSYLPQEILWGQEFRPVLAN--TSGTLSADFSLFHSVQI---CREQSHTAEKMQLEEEYRGGQGQ--------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "B7YZX2-1", "uniprot_id": "B7YZX2_DROME", "id": "B7YZX2-1", "name": "", "aln": "MQSDASPLGAAATDSLTMHRSTSMPVKPKPLEQKPLLRSSEKETVNASDYYPESPGFVRRRRSKAAGDHLETRSEQNPTFSFPYAHDWAGSTIELTPDLGSGPRTSSSDGLRRSLNRVMEKNGKENVVFRRIPEKSWRYMRDLVTTLMELEWKYMLTLFLGSYFLSWLLFAALCYVVAYSHGDFIFDPVSGKRMGEGVDPCIYGVHSWVAMIIYSVETQTTLGFGEKYASEECPETIFLFVMQMLSAALIEGCMVSVIYAKTARPARQLTKLKFSDKAVICYRDGRLCLLFRVCDPREQQSIESKIRVYIIVDKRTREGE---TIKSHVELKLEGNGE-QIILWPDVVCHVIDETSPLSQFTTAKLFNAAQFELYVSIVGTSPATAQMTEAKTSYLPREIFWGQRFVNIIHYDAQNERYIVDYENFNRTIS---VDMPMTNPKNDHLKLEYRK------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *::.*.*:.** : .: :::** **:::::*:* :*** .::.::*::*..: * :. :**: .:: **: *.: .. ::*:*:***:*:* : :**** :* :* *:: : * * :...: ** *** :: .:*** **: :.*: **:.:*.: *.. *:.:: :: : * **: :: *.::::...* ::: * .. **:** *** ::*. .* :*** : : .* :*: :::***:*.** ** .* :: . .*:. *. .:: :*: :** ", "identical_positions": 88, "similar_positions": 129, "identity": "18.68%" }, { "cls_id": "homologset.agr.MGI:1310002", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P50285-1", "uniprot_id": "FMO1_MOUSE", "id": "P50285-1", "name": "Flavin-containing monooxygenase 1", "aln": "----MVKRVAIVGAGVSGLASIKCCLEEG--LEPTCFERSSDLGGLWRFTEHV-----EEGRASLYKSVVSNSSREMSCYPDFPFPEDYPNFVPNSLFLEYLKLYSTQFNLQR---CIYFNTKVCSITKRPDFAVSGQWEVVTVTN--GKQNSAIFDAVMVCTGFLTNPHLPLDSFPGILTFKG-EYFHSRQYKHPDIFKDKRVLVVGMGNSGTDIAVEASHLAKKVFLSTTG--GAWVISRVFDSGYPWDMIFMTRFQNMLRNLLPTPIVSWLISKKMNSWFNHVNYGVAPEDRTQLREPVLNDELPGRIITGKVFIKPSIKEVKENSVVFNNTPKEEPIDIIVFATGYTFAFPFLDESVVKVEDGQASLYKYIFPAHLPKPTLAVIGLIKPLGSMVPTGETQARWVVQVLKGATTLPPPSVMMEEVNERK-KNKHSGFGLCYCKALQTDYITYIDDLLTSINAKPDLRAMLLTDPRLALSIFFGPCTPYHFRLTGPGKWEGARKAILTQWDRTVKVTKTRTIQESPSSFETLLKL---------FSFLALLIAVFLIFL--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P36365-1", "uniprot_id": "FMO1_RAT", "id": "P36365-1", "name": "Flavin-containing monooxygenase 1", "aln": "----MVKRVAIVGAGVSGLASIKCCLEEG--LEPTCFERSCDLGGLWRFTEHV-----EEGRASLYNSVVSNSSKEMSCYSDFPFPEDYPNFVPNSLFLEYLQLYATQFNLLR---CIYFNTKVCSITKRPDFAVSGQWEVVTVCQ--GKQSSDTFDAVMVCTGFLTNPHLPLDSFPGIQTFKG-QYFHSRQYKHPDVFKDKRVLVVGMGNSGTDIAVEASHLAKKVFLSTTG--GAWVISRVFDSGYPWDMIFMTRFQNMLRNLLPTPVVSWLISKKMNSWFNHVNYGVAPEDRTQLREPVLNDELPGRIITGKVLIKPSIKEVKENSVVFNNTPKEEPIDVIVFATGYSFAFPFLDESIVKVEDGQASLYKYIFPAHLPKPTLAVIGLIKPLGSMIPTGETQARWVVQVLKGATTLPPPSVMMKEVNERK-KNKHSGFGLCYCKALQSDYITYIDDLLTSINAKPDLRAMLLTDPRLALSIFFGPCTPYHFRLTGPGKWEGARKAILTQWDRTVNVTKTRTVQETPSTFETLLKL---------FSFLALLVAVFFIFL--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q01740-1", "uniprot_id": "FMO1_HUMAN", "id": "Q01740-1", "name": "Flavin-containing monooxygenase 1", "aln": "----MAKRVAIVGAGVSGLASIKCCLEEG--LEPTCFERSDDLGGLWRFTEHV-----EEGRASLYKSVVSNSCKEMSCYSDFPFPEDYPNYVPNSQFLEYLKMYANHFDLLK---HIQFKTKVCSVTKCSDSAVSGQWEVVTMHE--EKQESAIFDAVMVCTGFLTNPYLPLDSFPGINAFKG-QYFHSRQYKHPDIFKDKRVLVIGMGNSGTDIAVEASHLAEKVFLSTTG--GGWVISRIFDSGYPWDMVFMTRFQNMLRNSLPTPIVTWLMERKINNWLNHANYGLIPEDRTQLKEFVLNDELPGRIITGKVFIRPSIKEVKENSVIFNNTSKEEPIDIIVFATGYTFAFPFLDESVVKVEDGQASLYKYIFPAHLQKPTLAIIGLIKPLGSMIPTGETQARWAVRVLKGVNKLPPPSVMIEEINARK-ENKPSWFGLCYCKALQSDYITYIDELLTYINAKPNLFSMLLTDPHLALTVFFGPCSPYQFRLTGPGKWEGARNAIMTQWDRTFKVIKARVVQESPSPFESFLKV---------FSFLALLVAIFLIFL--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AA53ECJ5-1", "uniprot_id": "A0AA53ECJ5_DANRE", "id": "A0AA53ECJ5-1", "name": "Flavin-containing monooxygenase", "aln": "----MVKRVAVIGAGSSGLAAIKCCLDEG--LEPVCFESSDDIGGLWRFREKP-----ETDRCSIYHSLTVNTSKEMMCYSDFPVPDNFPNFMHNSLIVQYYRLYAEHFNLFE---HIHFQTTVRSVRQRPDFSVSGQWEVVTADRD-GQVETHMFDGVLVCVGHYTQPIKPLSEFPGIDTFPG-TVIHSWEYKKPDQYIGKKVLIIGIGNSGGDIAVELSRTCEKTFLSTRK--GSWVIGRMVEKGLPLDMMNISRVQDLMHCLIPRALVNWIGERSLNQRHDHKLYGLQPKHRILDHRPVINDDLPGRILVGELVLKPNVQTFHGSTVVFDDGSIEEKIDAVILCTGYDYKFPFLPDSLNSSADGGMKLYRRIFPPSLERPTLAIIGLLQTRGPIMPAAELQARWATRVIKGLNHLPSAEKMSKRIEKDI-KPYLKSHPCPKLASLQVDYIPYLDSIAKEVGACPNIAWLLMTDPALGLRVFLGPCTPYQFRLSGPGHWKGARQAILTQWERVAKPMKTRPIPE-PSSFSLLFWLGLSGGGAVILAIIALQKKIPLFMGIS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W1E9-1", "uniprot_id": "Q9W1E9_DROME", "id": "Q9W1E9-1", "name": "Flavin-containing monooxygenase", "aln": "-----MMSVCIIGAGTAGLCCARHSIANG--FETTVFELSDRIGGTWVYNEATGAVNGIDVHSSMYKNLRTNLPKEVMGFPDFEIGANEASYVRSDEICDFLNQYANHFDLKK---HIKFDSYVIRVLQR-----KTKWQVLFKDLVTNKIEFQYFDKVLVANGHYHTPN--YSQIPNMERFKG-QFLHSHDFRSREVFEGKSVLVIGAGPSGMDLSNIISRTADRVTISHHL--TDIGQHSFFEN---------------------------------------------------------------------VQQKPDVRELDEKGAFFVDGS-YQEFDTVFFCTGYKYAFPFLTVDSGIYVEDNYVQELYKQCINIRNPSMALIGLPFYVCAAQ-MMDIQARFIMSYYNGSNELPSTEDMLKDTRDRMGKLWAEGLRKRHAHMLGPKQIDYFTDLSQTAGVK-NIKPVMTKLHNESSKCFN--ENLLHFREDNFAILDDETFIKLN-----------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38866-1", "uniprot_id": "FMO1_YEAST", "id": "P38866-1", "name": "Thiol-specific monooxygenase", "aln": "MTVNDKKRLAIIGGGPGGLAAARVFSQSLPNFEIEIFVKDYDIGGVWHYPEQK------SDGRVMYDHLETNISKKLMQFSGFPFEENVPLYPSRRNIWEYLKAYYKTFIANKDAISIHFSTEVTYLKKK-----NSQWEITSKDE--LRTTKSDFDFVIVASGHYSVPKLPTNIAGLDLWFDNKGAFHSKDFKNCEFAREKVVIVVGNGSSGQDIANQLTTVAKKVYNSIKEPASNQLKAKLIET----------------------------------------------------------------------VQTIDSADWKNRSVTLSDGRVLQNIDYIIFATGYYYSFPFIEPSVRLEVLGEGVTGDKHSSVNLHNLWEHMIYVKDPTLSFILTPQLVIPFPLSELQAAIMV---EVFCKSLPITTTFDSNACGTHNFPKGKDLEYYAELQELLNSIPRRVGHFEPVVWDDR-----------LIDLRNSSYTDKE-ERNVLLAEHAQALKKKKAPYFLPAPHT---------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.::*.* .**.. : . :* * . :** * : * :*. : * ::: :..* . : . : : :: . * * . * *.: * : : . :*:: : ** *:*. *. * . * . :** ::: : * *:::* * ** *:: : ..:. * ..:. . . . : : : :* :.:.*** : ***: . . : . :* : . : : :. : . : : . : .: . : .:* . . : ", "identical_positions": 45, "similar_positions": 104, "identity": "7.99%" }, { "cls_id": "homologset.agr.MGI:1310004", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97872-1", "uniprot_id": "FMO5_MOUSE", "id": "P97872-1", "name": "Flavin-containing monooxygenase 5", "aln": "---MAKKRIAVIGAGASGLTCIKCCLEEG--LEPVCFERSGDIGGLWRFQEAPEEG-----RASIYQSVVINTSKEMMCFSDYPIPDHYPNYMHNSQVLEYFRMYAKEFDLLK---YIQFKTTVCSVKKQPDFSTSGQWQVVTEC-EGKQQVDVFDGVLVCTGHHTDAHLPLESFPGIEKFKG--KYFHSRDYKNPVEFTGKRVIVIGIGNSGGDLAVEISHTAKQVFLSTRRGAWILNRVGKHGYPIDLLLSSRIMYYLSRICGPSLKNNYMEKQMNQRFDHEMFGLKPKHRALSQHPTVNDDLPNRIIAGLVKVKGNVKEFTETAAVFEDGSREDGIDVVIFATGYSFAFPFLEDSVKVVKN-KVSLYKKVFPPNLEKPTLAIIGLIQPLGAIMPISELQGRWATQVFKGLKKLPSQSEMMAEINKAREEMAKR-YVDSQRHTIQGDYIDTMEEIADLVGVRPNILPLVFTDPRLALRLLLGPCTPVQYRLQGPGKWAGARKTILTTEDRVRKPLMTRVVERDSSGGS------LVTVRVLMLAVAFFAVILAYF----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8K4C0-1", "uniprot_id": "FMO5_RAT", "id": "Q8K4C0-1", "name": "Flavin-containing monooxygenase 5", "aln": "---MAKKRIAVIGSGASGLTCIKCCLEEG--LEPVCFERSDDIGGLWRYQENPEKG-----RASIYKSVIINTSKEMMCFSDYPIPDHYPNFMHNSQVLEYFRMYAKEFGLLK---YIQFKTTVCSVKKQPDFSTSGQWQVVTEH-EGKQQVDVFDGVLVCTGHHTDPHLPLDSFPGIEKFKG--KYFHSREYKNPVEFTGKRVIVIGIGNSGGDLAVEISHTAKQVFLSTRRGAWILNRVGKRGYPIDILLSSRITNYLSKICGSALKNRYMEKQLNQRFDHEMFGLKPKHSALGQHPTINDDLPNRIISGLVKVKGNVKEFTETAAIFEDGSREDDIDVVIFATGYSFAFPFLEDSVKVVQN-KVSLYKKVFPPNLEKPTLAIIGLIQPLGAIMPISELQGRWATQVFKGLKKLPSQSEMMAEINKTREEMAKR-YVDSQRHTIQGDYIDTMEEIADLVGVRPNLLSLAFTDPKLAFQLLVGPCTPVQYRLQGPGKWAGARKTILTTEDRIRKPLMTRVVERDSSGTS------LVTVRVLMLAVTFLAVILAYF----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P49326-1", "uniprot_id": "FMO5_HUMAN", "id": "P49326-1", "name": "Flavin-containing monooxygenase 5", "aln": "---MTKKRIAVIGGGVSGLSSIKCCVEEG--LEPVCFERTDDIGGLWRFQENPEEG-----RASIYKSVIINTSKEMMCFSDYPIPDHYPNFMHNAQVLEYFRMYAKEFDLLK---YIRFKTTVCSVKKQPDFATSGQWEVVTES-EGKKEMNVFDGVMVCTGHHTNAHLPLESFPGIEKFKG--QYFHSRDYKNPEGFTGKRVIIIGIGNSGGDLAVEISQTAKQVFLSTRRGAWILNRVGDYGYPADVLFSSRLTHFIWKICGQSLANKYLEKKINQRFDHEMFGLKPKHRALSQHPTLNDDLPNRIISGLVKVKGNVKEFTETAAIFEDGSREDDIDAVIFATGYSFDFPFLEDSVKVVKN-KISLYKKVFPPNLERPTLAIIGLIQPLGAIMPISELQGRWATQVFKGLKTLPSQSEMMAEISKAQEEIDKR-YVESQRHTIQGDYIDTMEELADLVGVRPNLLSLAFTDPKLALHLLLGPCTPIHYRVQGPGKWDGARKAILTTDDRIRKPLMTRVVERSSSMTS------TMTIGKFMLALAFFAIIIAYF----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5TZD3-1", "uniprot_id": "Q5TZD3_DANRE", "id": "Q5TZD3-1", "name": "Flavin-containing monooxygenase", "aln": "----MAKRVAIIGGGTSGLACIKCCLDEG--LEPVCFETSDDIGGLWRFKENPDLD-----QASIYHSLIINTSKEMMCYSDYPIPAHFPNYMHNSLIMEYFRMYAENFQLKR---HIRFQTRVLHVTPRPDFPHSGQWDVETESKDGLREKQVFDAVMVCTGHHCHPHLPLKDFPGIDTFKG--KFFHSRDYKNPEDWRGKRAVVIGIGNSGGDIAVELSRMAKQVYLSTRKGSWILNRVGDSGVPFDMMFNNRAVMWFLDSLPVKYRNKLGESRLNKRFDHKLYGLQPEHRIFSQHPMVNDDLPNRILSGTVSVKPNVQEFRGSSVVFEDGTVEDNIDLVVFATGYTFSFPFLSSHVIPVSNNKVSLYKFVYPPGLERSTLAVIGLIQPLGAIMPISEMQARWATRVFKGLCKLPSKNAMMKDIKAKEQAMTQR-YVAAQRHTIQVDYIPYMDELAKQVGVRPSIPRLLLTDPRLAFKVIFGPCTPYQFRLHGPGQWEGARQAILTQWDRVVEPLKTRCTKEPQSQSFSHSLIFSVSVAGLLSALYYGRASLQTFLENPSALLDKIRGFVPLPMPTQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W1E9-1", "uniprot_id": "Q9W1E9_DROME", "id": "Q9W1E9-1", "name": "Flavin-containing monooxygenase", "aln": "-----MMSVCIIGAGTAGLCCARHSIANG--FETTVFELSDRIGGTWVYNEATGAVNGIDVHSSMYKNLRTNLPKEVMGFPDFEIGANEASYVRSDEICDFLNQYANHFDLKK---HIKFDSYVIRVLQRKTKWQVLFKDLVTNK----IEFQYFDKVLVANGHYHTPNY--SQIPNMERFKG--QFLHSHDFRSREVFEGKSVLVIGAGPSGMDLSNIISRTADRVTISHHLT---------------------------------------------------------------------DIGQHSFFENVQQKPDVRELDEKGAFFVDGS-YQEFDTVFFCTGYKYAFPFLTVDSGIYVEDNYVQELYKQCINIRNPSMALIGLPFYVCAAQ-MMDIQARFIMSYYNGSNELPSTEDMLKDTRDRMGKLWAEGLRKRHAHMLGPKQIDYFTDLSQTAGVKN--------------------IKPVMTKLHNESSKCFNENLLHFREDNFAILDDETFIKLN------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38866-1", "uniprot_id": "FMO1_YEAST", "id": "P38866-1", "name": "Thiol-specific monooxygenase", "aln": "MTVNDKKRLAIIGGGPGGLAAARVFSQSLPNFEIEIFVKDYDIGGVWHYPEQKSDG------RVMYDHLETNISKKLMQFSGFPFEENVPLYPSRRNIWEYLKAYYKTFIANKDAISIHFSTEVTYLKKKNSQWEITSKDELRTT------KSDFDFVIVASGHYSVPKLP-TNIAGLDLWFDNKGAFHSKDFKNCEFAREKVVIVVGNGSSGQDIANQLTTVAKKVYNSIKEP------------------------------------------------------------------ASNQLKAKLIETVQTIDS--ADWKNRSVTLSDGRVLQNIDYIIFATGYYYSFPFIEPSVRLEVLGEGVTGDKHSSVNLHNLWEHMIYVKDPTLSFILTPQLVIPFPLSELQAAIMVEVFCKSLPITTTFDSNACGT------HNFPKGKDLEYYAELQELLNSIPRRVG--------HFEPVVWDDRLIDLRNSSYTDKEERNVLLAEHAQALKKKKAPYFLPAPHT----------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.:**.* .** . : . :* * *** * : * :*. : * .*::* :..: : : . : : :::. * : * : *:*.: * : : : . ** *:*..**: .: .:..:: : . :**::::. * .:::* * ** *:: :: *.:* * : :: : : . : .. : ** : :* :.*.*** : ***: : .:.. :* : : :: : :. : : : . : :: . . : . . . : : . ", "identical_positions": 49, "similar_positions": 114, "identity": "8.46%" }, { "cls_id": "homologset.agr.MGI:1312921", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35397-1", "uniprot_id": "CASP6_RAT", "id": "O35397-1", "name": "Caspase-6", "aln": "----------------------------MTETDGFYRSREVLDPAEQYKMDHKRRGTALIFNHERFFWHLALPERRGTNADRDNPTRRFSELGFEVKCFNDLRAEELLLKIHEVSTSSHVDADCFLCVFLSHGEGNHIYAYDAKIEIQTLTGLFKGDKCQSLVGKPKIFIIQACRGSQHDVPLVPLDVVDHQTDKLDDNVTQVDAASVYTLPAGADFLMCYSVAEGYYSHRETVNGSWYIQDLSEMLARHGS-------SLEFTELLTLVNRKVSQRRVDFCKDPGAIGKKQVPCFASMLTKKLHFCPKPSK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O08738-1", "uniprot_id": "CASP6_MOUSE", "id": "O08738-1", "name": "Caspase-6", "aln": "----------------------------MTETDGFYKSREVFDPAEQYKMDHKRRGVALIFNHERFFWHLTLPERRGTNADRDNLTRRFSDLGFEVKCFNDLRAEELLLKIHEVSTSSHIDADCFICVFLSHGEGNHVYAYDAKIEIQTLTGLFKGDKCQSLVGKPKIFIIQACRGSQHDVPVVPLDMVDHQTDKLDN-VTQVDAASVYTLPAGADFLMCYSVAEGYYSHRETVNGSWYIQDLCEMLARYGS-------SLEFTELLTLVNRKVSQRRVDFCKDPDAIGKKQVPCFASMLTKKLHFCPKPSK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P55212-1", "uniprot_id": "CASP6_HUMAN", "id": "P55212-1", "name": "Caspase-6", "aln": "--MSSASGLRRG--------HPAGGEENMTETDAFYK-REMFDPAEKYKMDHRRRGIALIFNHERFFWHLTLPERRGTCADRDNLTRRFSDLGFEVKCFNDLKAEELLLKIHEVSTVSHADADCFVCVFLSHGEGNHIYAYDAKIEIQTLTGLFKGDKCHSLVGKPKIFIIQACRGNQHDVPVIPLDVVDNQTEKLDTNITEVDAASVYTLPAGADFLMCYSVAEGYYSHRETVNGSWYIQDLCEMLGKYGS-------SLEFTELLTLVNRKVSQRRVDFCKDPSAIGKKQVPCFASMLTKKLHFFPKSN--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N2M7-1", "uniprot_id": "A0A8M1N2M7_DANRE", "id": "A0A8M1N2M7-1", "name": "Caspase-6", "aln": "--MATNTRSHES--------------ENITETDGRIQSVY---PNQEYDMRHARRGMALIFNQKQFDWKLGLKTRNGTDKDRDDLVSRFQELNFEVKAYNDYSRDDVLLKIQEASAADHVDADCFVCIFLSHGEDGHVYANDKKIEIPEITDLFKGDKCRSLVGKPKIFIWQACRGDKLDDAVTEMSVED--------VEMAVDAGVLYTLPAGADFIMCYSTAEGFCSFREPLNGSWYIQDLCEILGRYHS-------ELQFTDILTLVNMKVSLRSVPNCRNRAAIGKKQMPCFASMLTKRLFFRDNTQIQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32TEP7-1", "uniprot_id": "A0AB32TEP7_DANRE", "id": "A0AB32TEP7-1", "name": "Caspase-6", "aln": "--MASHTKSDGSAVEKDSASAGQTVEENLTETDSFNQSIFSMDPNQEYDMNHKRRGMALIFNHENFFWKLGLGYRSGTNADKENLIRRFRELNFEVKAFDDYKRHEVLSKITEAAAADHVDADCFVCVFLSHGENGHVYANDGQIEIPEITDLFKGDKCRSLVGKPKIFIWQACRGDKHDDPVTPMDVVDSQV----TNDMVVDAGVLYTLPAGADFIMCYSVAEGYYSHRETVNGSWYIQDLCEILRRYGS-------ELEFAEILTLVNRKVSLRSVLNCKDRSAVGKKQVPCFASMLTKKLFFRPKK---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VET9-1", "uniprot_id": "Q9VET9_DROME", "id": "Q9VET9-1", "name": "", "aln": "MDDTDFSLFGQKNKHKKDKADATKIAHTPTSELDLKRIIISRPTNEDTYENCARAGIALILNHKDVK---GQKQRVGTERDRDDMEATLQGFGFDVRTFDDLTFSEINDTLKEVAREDHSQNDCFVLAVMSHGTEGKVYAKDMSYPVERLWNPFLGDNCKTLKNKPKLFFIQACRGANLEKAVEFSSFAVMTRELVPEPAAAVQP-ITYAIPSTADILVFYSTFDKFFSFRNVDDGSWFIQSLCRVLDQAAANEAATPEGVELLRLLTAVNRKVAYEYQSNTKNEALNQMKEMPNFMSTLTKTFQLRVKPKT-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. : . :. * * ***:*:: . * ** *::: : :.*:*: ::* :: .: *.: .* : ***: .:*** .::** * . : : . * **:*::* .***:*: ***** : : .: .. *:. *::*: **::: **. : : *.*: :***:**.*..:* : : ::: :** ** **: . :: *::* * * *** : : : ", "identical_positions": 68, "similar_positions": 83, "identity": "21.73%" }, { "cls_id": "homologset.agr.MGI:1312922", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q920D5-1", "uniprot_id": "CASPC_RAT", "id": "Q920D5-1", "name": "Caspase-12", "aln": "-MAAKRTHERDPIYKIKGLAKDMLDGVFDDLMDKNVLNGDELLKIGEGASLILSKAENLVESFFEKTEMAGKIFAGHIANSDKQLSLQFPSDDEEDELQKMFTPSSASESRGKVEDEEMEVNVGVAHASHLMLTVPQGIQSTEVQDSLKLCSRDWFCTMKTERAEEIYPVMEKEGRTRLALIICNKKFD-YLFDRDDAETDILNMKELLQNLGYSVVIKENLTAQEMETELMKFAGRPEHQSSDSTFLVFMSHGILEGICGVKHR--NKKPDVLHDDTIFTIFNNSNCPSLRNKPKILIMQACRGRHTGTIWVSTSKGIATADTDEECVLSHRWNNSITKAHVETDFIAFKSSTPHNISWKVGKSGSLFISKLIDCFKKYCWCYHLEEIFRKVQYSFEVP---GELTQMPTIERVSMTRYFYLFPGN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O08736-1", "uniprot_id": "CASPC_MOUSE", "id": "O08736-1", "name": "Caspase-12", "aln": "-MAARRTHERDPIYKIKGLAKDMLDGVFDDLVEKNVLNGDELLKIGESASFILNKAENLVENFLEKTDMAGKIFAGHIANSQEQLSLQF-SNDEDDGPQKICTPSSPSESKRKVEDDEMEVNAGLAHESHLMLTAPHGLQSSEVQDTLKLCPRDQFCKIKTERAKEIYPVMEKEGRTRLALIICNKKFD-YLFDRDNADTDILNMQELLENLGYSVVLKENLTAQEMETELMQFAGRPEHQSSDSTFLVFMSHGILEGICGVKHR--NKKPDVLHDDTIFKIFNNSNCRSLRNKPKILIMQACRGRYNGTIWVSTNKGIATADTDEERVLSCKWNNSITKAHVETDFIAFKSSTPHNISWKVGKTGSLFISKLIDCFKKYCWCYHLEEIFRKVQHSFEVP---GELTQMPTIERVSMTRYFYLFPGN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6UXS9-1", "uniprot_id": "CASPC_HUMAN", "id": "Q6UXS9-1", "name": "Inactive caspase-12", "aln": "-MADEKPSNGVLVHMVKLLIKTFLDGIFDDLMENNVLNTDEIHLIGKCLKFVVSNAENLVDDITETAQIAGKIFREHLWNSKKQLSSDISSDGERE-----------ANMPG--------------------------------------------------------------------LNIRNKEFN-YLHNRNGSELDLLGMRDLLENLGYSVVIKENLTAQEMETALRQFAAHPEHQSSDSTFLVFMSHSILNGICGTKHW--DQEPDVLHDDTIFEIFNNRNCQSLKDKPKVIIMQACRGNGAGIVWFTTDSGKASADTHGRLLQGNICNDAVTKAHVEKDFIAFKSSTPHNVSWRHETNGSVFISQIIYYFREYSWSHHLEEIFQKVQHSFETP---NILTQLPTIERLSMTRYFYLFPGN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9I9L7-1", "uniprot_id": "CASPA_DANRE", "id": "Q9I9L7-1", "name": "Caspase a", "aln": "MAKSIKDHLQDALSNIGADNLRRFQSRLGDRKQEPRVRKSTIEKLKDEIDLVDLLVNTFTS---DAVSVTVDILRGIKCNAVAEELLENTGQGGVSQPEPPVPEPIPKDPAQLKELKVTP------------------------------CSQQFKNKILREKGQETYEIKDKSVRKRLALLINNVDFDDKAMKRSGSEKDEENMEKLLKELDYQVVKRPNLSAKEMDEAIRDFAQREEHKYSDSAFVVIMSHGKRDAIMGVHYHRTNNPSDSFPVDNVYRRLNSENCPALRDKPKVILIQACRGGEHGRVWASDGEPDEPIEIEDD-----------DFVHKEKDFISLMSCTPDTKSYRHVQNGTFYVQTLVDVFIKCAHEDHIEELFRKVLRRFEHPNMIGNFKQMACKDRATLPKLFYLFPGL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : ::. :.* :: :. . : : . .:: .:.:.. : ..:: .*: *: : : .:. . : * * * .*: .*..:: * .*..**::*.*.** : **:*:**: : .** : **: ***:*:*:***. :.* *.:: :: .* : *.:: :*. ** :*::***::::***** * :* : .. . : . .* *.***:: *.**.. *:: .*:.::. :: * : . *:**:*:** ** * . :.*:. :* ::.: ****** ", "identical_positions": 79, "similar_positions": 126, "identity": "18.5%" }, { "cls_id": "homologset.agr.MGI:1312985", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XFX0-1", "uniprot_id": "TAGL2_RAT", "id": "Q5XFX0-1", "name": "Transgelin-2", "aln": "--MANRGPSYGLSREVQQKIEKQYDPDLEQILIQWITTQCRKGVSQPQPGRENFQNWLKDGTVLCELINSLYPEGQAPVKKIQA--STMAFKQMEQISQFLQAAERYGINTTDIFQTVDLWEGKNMACVQRTLMNLGGLAVARDDGLFSGDPNWFPKKSKENPRNFSDNQLQEGKNVIGLQMGTNRGASQAGMTGYGMPRQIL---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P37802-1", "uniprot_id": "TAGL2_HUMAN", "id": "P37802-1", "name": "Transgelin-2", "aln": "--MANRGPAYGLSREVQQKIEKQYDADLEQILIQWITTQCRKDVGRPQPGRENFQNWLKDGTVLCELINALYPEGQAPVKKIQA--STMAFKQMEQISQFLQAAERYGINTTDIFQTVDLWEGKNMACVQRTLMNLGGLAVARDDGLFSGDPNWFPKKSKENPRNFSDNQLQEGKNVIGLQMGTNRGASQAGMTGYGMPRQIL---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9WVA4-1", "uniprot_id": "TAGL2_MOUSE", "id": "Q9WVA4-1", "name": "Transgelin-2", "aln": "--MANRGPSYGLSREVQQKIEKQYDADLEQILIQWITTQCREDVGQPQPGRENFQKWLKDGTVLCKLINSLYPEGQAPVKKIQA--SSMAFKQMEQISQFLQAAERYGINTTDIFQTVDLWEGKNMACVQRTLMNLGGLAVARDDGLFSGDPNWFPKKSKENPRNFSDNQLQEGKNVIGLQMGTNRGASQAGMTGYGMPRQIL---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9VZI1-1", "uniprot_id": "Q9VZI1_DROME", "id": "Q9VZI1-1", "name": "Transgelin", "aln": "-MASNRAAKSGFAAEAQRKINSKYSEELAQESLEWIKAVTEEPINTSG-DTDNFFEVLKDGVILCKLANALQP---GSIKKINE--SKMAFKCMENISAFLACAKNFGVPTQETFQSVDLWERQNLNSVVICLQSLG-----RKASNFN-KPSIGPKEADKNVRNFSDEQLRAGANVISLQYGSNKGATQSGIN-FGNTRHM----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P14318-1", "uniprot_id": "MP20_DROME", "id": "P14318-1", "name": "Muscle-specific protein 20", "aln": "---------MSLERAVRAKIASKRNPEMDKEAQEWIEAIIAEKF----PAGQSYEDVLKDGQVLCKLINVLSP---NAVPKVNS--SGGQFKFMENINNFQKALKEYGVPDIDVFQTVDLYEKKDIANVTNTIFALG--RATYKHADFK-GPFLGPKPADECKRDFTEEQLKAGQTIVGLQAGSNKGATQAGQN-LGAGRKILLGK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9I7J0-1", "uniprot_id": "Q9I7J0_DROME", "id": "Q9I7J0-1", "name": "Calponin-homology (CH) domain-containing protein", "aln": "--------------------MAPRNKEQEQEVLNWVFAVIGEKV----PSGQ-YEDILKDGIWLCKLANKLAP---GSVKKIQE--RGTNFQLMENIQRFQAAVKKYGVPEEEIFQTADLFERRNIPQVTLSLYALG--RITQKHPEYT-GPTLGPKMADKNERSFTEEQLRAHEGELNLQMGFNKGASQAGHGGMGNTRHM----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08873-1", "uniprot_id": "SCP1_YEAST", "id": "Q08873-1", "name": "Transgelin", "aln": "MSYDKKADVTSLDEDLRQLRESKFSPEAIQNIKIWVYKSVLKEIAP----PGDLLECLKDGTVLCKLANILYEADTGEANHISWKSSKMPFVQMDQISQFLSFSRKYGVPEDELFQTIDLFEKKDPAIVFQTLKSLSRYANKKHTDRFPVLGPQLSTKKPRPPVKSKPKHLQDGTGWSTFEYGYMKGASQATEGVVLGQRRDIV--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : *: : . . **** **:* * * ::. * *::*. * ..:*: : **: **:* :: * : *. . : .. . . . ::*: :: * :**:*: *: ", "identical_positions": 28, "similar_positions": 41, "identity": "13.59%" }, { "cls_id": "homologset.agr.MGI:1313136", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O55156-1", "uniprot_id": "CLIP2_RAT", "id": "O55156-1", "name": "CAP-Gly domain-containing linker protein 2", "aln": "-------------------------------------------MQKPSGLKPPGRGGKHSSPVGRPSIGSASSSVVASASGSKEGSPLHKQASGPSSAGATTTVSEKPGPKAAEVGDDFLGDFVVGERVWVNGVKPGVVQYLGETQFAPGQWAGVVLDDPVGKNDGAVGGLRYFECPALQGIFTRPSKLTRQPAAEGSGSDGHSVESLTAQNLSLHSGTATPPLTGRVIPLRESVLNSSVKTGNESGSNLSDSGSVKRG-DKDLHLGDRVLVG---GTKTGVVRYVGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCPPKFGLFAPIHKVIRIGFPSTSPAKAKKTKRMAMGVSALTHSPSSSS------------ISSVSSVASSVGGRPSRSGLLTETSSRYARKISG-----------TTALQEALKEKQQHIEQLLAERDLERAEVAKATSHICEVEKEIALLKAQHEQYVAEAEEKLQRARLLVENVR---------------------------------KEKVDLSNQLEEERRKVEDLQFR------VEEESITKGDLETQTQLEHARIGELEQSLLLEKAQAERLLRELADNRLTTVAEK-----------------------------SRVLQLEEELSLRRGEIEELQHCLLQSGPPPADHPE------AAETLRLR-----------------------------------ERLLSASKEHQRDSTLLQDKYEHMLKTYQTE-------------------------------------------------VDKLRAANEKYAQEVADLKAKVQQATTENMGLMDNWKSKLDSLASDHQKS----------LEDLKATLNSGPGAQQKEIG-------ELKALVEGIKMEHQLELGNLQAKHDLETAMHG-------------------------------------------------------KEKEGLRQKLQEAQEELAGLQQHWRAQLEEQA-----------------------------------AAP-AELQEAQDQCRDAQLRVQELEGLDV--------------------------EYRGQAQAIEFLKEQISLAEKKMLDYEMLQRAEAQSRQEAERLREKLLVAENRLQAVESLCS--------------------------------------------------------------------AQHSHVIESNDLSEEKIRMKETVEGLQDKLNKRDKEVAALTSQMDMLRAQVSALENKCKSG---------------------EKKIDSLLKEKRRLEAELEAVSRKTHDASGQLVHIS---------------------------------------------------------------QELLRKERSLNELRVLLLEANRHSPGPERDLSREVHKAEWR-IKEQKLKDDIRGLREKLTGLDKE---KSLSEQKRYSLIDP-----------------------ASAPELLRLQHQLVSTEGCLRDALDQAQQVERLVEALRGCSDRTQTISNSGSANGIHQPDKAHKQEDKH------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z0H8-1", "uniprot_id": "CLIP2_MOUSE", "id": "Q9Z0H8-1", "name": "CAP-Gly domain-containing linker protein 2", "aln": "-------------------------------------------MQKPSGLKPPGRGGKHSSPVGRPSVGSASSSVVASTSGSKEGSPLHKQASGPSSSGAATTVSEKPGPKAAEVGDDFLGDFVVGERVWVNGVKPGVVQYLGETQFAPGQWAGVVLDDPVGKNDGAVGGVRYFECPALQGIFTRPSKLTRQPTAEGSGSDTHSVESLTAQNLSLHSGTATPPLTGRVIPLRESVLNSSVKTGNESGSNLSDSGSVKRG-DKDLHLGDRVLVG---GTKTGVVRYVGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCPPKFGLFAPIHKVIRIGFPSTSPAKAKKTKRMAMGVSALTHSPSSSS------------ISSVSSVASSVGGRPSRSGLLTETSSRYARKISG-----------TTALQEALKEKQQHIEQLLAERDLERAEVAKATSHICEVEKEIALLKAQHEQYVAEAEEKLQRARLLVENVR---------------------------------KEKVDLSNQLEEERRKVEDLQFR------VEEESITKGDLETQTQLEHARIGELEQSLLLEKAQAERLLRELADNRLTTVAEK-----------------------------SRVLQLEEELSLRRGEIEELQHCLLQSGPPPADHPE------AAETLRLR-----------------------------------ERLLSASKEHQRDSTLLQDKYEHMLKTYQTE-------------------------------------------------VDKLRAANEKYAQEVADLKAKVQQATTENMGLMDNWKSKLDSLASDHQKS----------LEDLKATLNSGPGAQQKEIG-------ELKALVEGIKMEHQLELGNLQAKHDLETAMHG-------------------------------------------------------KEKEGLRQKLQEVQEELAGLQQHWREQLEEQA-----------------------------------SQHRLELQEAQDQCRDAQLRAQELEGLDV--------------------------EYRGQAQAIEFLKEQISLAEKKMLDYEMLQRAEAQSRQEAERLREKLLVAENRLQAAESLCS--------------------------------------------------------------------AQHSHVIESSDLSEETIRMKETVEGLQDKLNKRDKEVTALTSQMDMLRAQVSALENKCKSG---------------------EKKIDSLLKEKRRLEAELEAVSRKTHDASGQLVHIS---------------------------------------------------------------QELLRKERSLNELRVLLLEANRHSPGPERDLSREVHKAEWR-IKEQKLKDDIRGLREKLTGLDKE---KSLSEQRRYSLIDP-----------------------ASPPELLKLQHQLVSTEDALRDALNQAQQVERLVEALRGCSDRTQTISNSGSANGIHQPDKAHKQEDKH------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UDT6-1", "uniprot_id": "CLIP2_HUMAN", "id": "Q9UDT6-1", "name": "CAP-Gly domain-containing linker protein 2", "aln": "-------------------------------------------MQKPSGLKPPGRGGKHSSPMGRTSTGSASSSAAVAAS-SKEGSPLHKQSSGPSSSPAAAAAPEKPGPKAAEVGDDFLGDFVVGERVWVNGVKPGVVQYLGETQFAPGQWAGVVLDDPVGKNDGAVGGVRYFECPALQGIFTRPSKLTRQPTAEGSGSDAHSVESLTAQNLSLHSGTATPPLTSRVIPLRESVLNSSVKTGNESGSNLSDSGSVKRG-EKDLRLGDRVLVG---GTKTGVVRYVGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCPPKFGLFAPIHKVIRIGFPSTSPAKAKKTKRMAMGVSALTHSPSSSS------------ISSVSSVASSVGGRPSRSGLLTETSSRYARKISG-----------TTALQEALKEKQQHIEQLLAERDLERAEVAKATSHICEVEKEIALLKAQHEQYVAEAEEKLQRARLLVESVR---------------------------------KEKVDLSNQLEEERRKVEDLQFR------VEEESITKGDLETQTQLEHARIGELEQSLLLEKAQAERLLRELADNRLTTVAEK-----------------------------SRVLQLEEELTLRRGEIEELQQCLLHSGPPPPDHPD------AAEILRLR-----------------------------------ERLLSASKEHQRESGVLRDKYEKALKAYQAE-------------------------------------------------VDKLRAANEKYAQEVAGLKDKVQQATSENMGLMDNWKSKLDSLASDHQKS----------LEDLKATLNSGPGAQQKEIG-------ELKAVMEGIKMEHQLELGNLQAKHDLETAMHV-------------------------------------------------------KEKEALREKLQEAQEELAGLQRHWRAQLEVQA-----------------------------------SQHRLELQEAQDQRRDAELRVHELEKLDV--------------------------EYRGQAQAIEFLKEQISLAEKKMLDYERLQRAEAQGKQEVESLREKLLVAENRLQAVEALCS--------------------------------------------------------------------SQHTHMIESNDISEETIRTKETVEGLQDKLNKRDKEVTALTSQTEMLRAQVSALESKCKSG---------------------EKKVDALLKEKRRLEAELETVSRKTHDASGQLVLIS---------------------------------------------------------------QELLRKERSLNELRVLLLEANRHSPGPERDLSREVHKAEWR-IKEQKLKDDIRGLREKLTGLDKE---KSLSDQRRYSLIDR-----------------------SSAPELLRLQHQLMSTEDALRDALDQAQQVEKLMEAMRSCPDKAQTIGNSGSANGIHQQDKAQKQEDKH------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q4W2-1", "uniprot_id": "A0A8M9Q4W2_DANRE", "id": "A0A8M9Q4W2-1", "name": "", "aln": "-----------------------------------------MNMLKSSGLKIPGRGPKHASPVGRTTAGPSTS-----PAAQKEGCPYKQTTPTPSSN-----ASDKSSSKASEVGDEVAGDFVVGERVWVNGVKPGVIAYLGETQFSPGQWAGVVLNDLVGKNDGSVNGVRYFECQALQGIFTRPSKLTRQPIGDGSDEQ---------QNAQLQGGAGASGQR-VVMPLREGILNSSVKTGNESGSNMSDSGSVKKGGEKDLKVGDRVLVG---GTKTGVVRYVGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCPPKFGLFAPIHKVIRIGFPSTSPAKAKKSKRMAMGVSSLAHSPSSSS------------ISSVSSVASSVGGRPSRTGLLTETSSRYARKISG-----------TTALQEALKEKQQHIEQLLAERDLERAEVAKATSHICEVEKELAALKARHLQYATETESNLQQVRAMLASTQ---------------------------------KDKMELANQLEEEKRKVEDLQFR------VEEESITKGDLETQTKLEHARIRQLEQCLHLEKSKAERLQKELEEKMQTTVEEK-----------------------------TRVMQLEEELALRKAEVEELQVRFQRGSSGSATDAEDGEPGITSETLVLR-----------------------------------EQLLSVGRERREESSQLRERYEASLSTSQKE-------------------------------------------------IERLKAITERQGQEISDLKQRLQQATRENMEMMDSWKAKLDALVGDHQRA----------LEELKASLTTDCGSGEINGGEGEGSLPEMRAALEGLKMEHQLELENLKAKHEIDAAVMA-------------------------------------------------------KEREDLRSRLQELRDQLEDSEENWKIQVETKS-----------------------------------NQHTLEIKEVSEKLQKAELRIVDLDKSHE--------------------------ERE---KVNQLLKEQLMLAEKKMVDYEALQKAEAQSRAEILSLQEKLRVTENRLQAVEADHT--------------------------------------------------------------------TQDVNMIENNDNSDEKVKLKQNVEETLEKLTKREKEVSTLTTQVDALKTQITALEEKVRLG---------------------EKTADGLIKEKTRLEAELETMTKKSHDASGQLVNIS---------------------------------------------------------------QELLKKERSLNELRVLLLESPRHSAGVDRDLSREVHRAEWR-MKEQKLQDDIKTLREKLLLLGRE---RSSPDHRRYSMMDPS----------------------ASDTEVARLRQRLLNTEDALRNALEHNQHVDQLVQAMRTRPDKNQAHASANSANGIHQEDTSFTQEEEH------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VJE5-1", "uniprot_id": "CL190_DROME", "id": "Q9VJE5-1", "name": "Restin homolog", "aln": "MSDDTSASGGTSAPFPSPVTADPEPGATASKLPGPIRSNIPTPATSGTGIPQPSKMKAPSSFGSTGSVSKIGRPCCNHTTPKSGPPPREATSMSRESDDNLSSINSAYTDNSSAVLTANTEQFIIGQRVWLGGTRPGQIAFIGDTHFAAGEWAGVVLDEPNGKNDGCVSGKRYFQCEPKRGIFSRLTRLTTYPLAG--------------AQTPTSPLAKSSPDRSRTVSPTASIRSSMLRSPGIGG-------------KNGMAVGDRVIVSSGFGSRPGILRYLGETQFAPGNWCGVELDEPSGKNDGTVDDIRYFECKPKYGVFVPIAKVSLSPSSKKTRLSRTGSRESLTSIGTMNSIATTATSRMRMNAQQRKSSTPVKPILATPKSQFSMQDLLREKQQHVEKLMVERDLDREDAQNQALQLQKNINELKARIVELESALDNERKKTEELQCSIDEAQFCGDELNAQSQVYKEKIHDLESKITKLVSATPSLQSILPPDLPSDDGALQEEIAKLQEKMTIQQKEVESRIAEQLEEEQRLRENVKYLNEQIATLQSELVSKDEALEKFSLSECGIENLRRELELLKEENEKQAQEAQAEFTRKLAEKSVEVLRLSSELQNLKATSDSLESERVNKTDECEILQTEVRMRDEQIRELNQQLDEVTTQLNVQKADS--SALDDMLRLQKEGTEEKSTLLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQEKLVREMTENAINQIQLEKESIEQQLALKQNELEDFQKKQSESEVHLQEIKAQNTQKDFELVESGESLKKLQQQLEQKTLGHEKLQAALEELKKEKETIIKEKEQELQQLQSKSAESESALKVVQVQLEQLQQQAAASGEEGSKTVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKSGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEITDTLHAELQAERSSSSALHTKLSKFSDEIATGHKELTSKADAWSQEMLQKEKELQELRQQLQDSQDSQTKLKAEGERKEKSFEESIKNLQEEVTKAKTENLELSTGTQTTIKDLQERLEITNAELQHKEKMASEDAQKIADLKTLVEAIQVANANISATNAELSTVLEVLQAEKSETNHIFELFEMEADMNSERLIEKVTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLLEKGNEFDTQLAEYQKVIDEMDDAASVKSALLEQLQNRVAELETALRQANDAQKTAYLETKELRRQLESLELEKSREVLSLKAQMNGASSRSGKGDEVESLDIETSLAKINFLNSIIADMQQKNDALKAKVQTLETLPMDFTKPHAFDALTKRKPAPRLFCDICDEFDQHDTEDCPIQGSEDQDYSTPSSESNNNEKERKLPAPRKYCDSCEVFGHDTSECADDETY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :*: *.: :* . : . .: .. * . : .* . ::: * :*::*:***:.*.:** : ::*:*:*:.*:******:: *****.*.* ***:* . :***:* ::** * . : : :. .:. .: .* ::: . .* .:.: :****:*. *::.*::**:***:** *:********* *****:* . ***:* **:*:*.** ** ...: . . ::. .:.:: .:::: :.*..: :: .: * .** *...: : : : **: ::* : :* :* : * ** :. : . * *.: *:*: * : .. .: :: . : : :::*****:* *:::: ::.* ::*.: : .*... * :*.: * * * : *: :* : .: ** . *: *: :* ::.**: : . . . : * *: *: :* :: .:. ::: * :. * * :.:*: *: *: ::: . *: ::.. : :*: * .. .: **:*: :. . . :::: * : * : **:** . * ** * . .: :::: : ::: : *::* :: :.:: .*. . : *:*:: ::: :: . * : :** : * * : *:: .:.*.:: : ::. *.. .:: . ::.:: :.:.:::: * * : : : * : * . . :*. . * :* :*..**: : . . * ...** :. : * :**..*:**: * *: . .:. .. .: * **:.*::: * *:* * : . . ::: ::: . . : :*:::: . * .**:* : : . : :* : : . . * : : .:. : ", "identical_positions": 203, "similar_positions": 381, "identity": "11.81%" }, { "cls_id": "homologset.agr.MGI:1313138", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZRJ4-1", "uniprot_id": "D3ZRJ4_RAT", "id": "D3ZRJ4-1", "name": "Olfactory receptor", "aln": "MDIGNCS-LNEFIFVGVTNNPEMKGTLFTIFLLIYLINLLGNLGMIILIRMDPQLHTPMYFFLSHLSFCDLCYSTAIGPKMLVDMFGKNKSIPFWGCALQLFIFCTFADSECVLLAVMAFDRYQAISNPLLYTVNMSSRKCFMLMAGVYLVGTSDALIHTTLAFRLCFCGSNEINHFFCDLPPLYLLSCSDTQVNYLVLFTVYGFLELSTISGVLVSYCYIIASVFKIRSTEGRLKAFSTCTSHLTAVAIFQGTLLFTYFRPSSSYSLDQDKMTSLFYTLVIPMLNPLIYSLRNKDVKEALEKIKRKSWF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TR48-1", "uniprot_id": "Q7TR48_MOUSE", "id": "Q7TR48-1", "name": "Olfactory receptor", "aln": "MNIGNCS-LNEFIFVGVTNNPEMKGTLFTIFLLIYLINLLGNIGMIILIRMDPQLHTPMYFFLSHLSFCDLCYSTAIGPKMLVDMFGKNKSIPFWGCAVQFFISCTFADSECVLLAVMAFDRYQAISNPLLYTANMSSRKCFMFMAGVYLVGTSDALIHTTLAFRLCFCGSNEINHFFCDLPPIYLLSCSDTQVNYLALFTIYGFLELSTISGVLVSYCYIISSVLKIRSTEGRFKAFSTCTSHLTAVAIFQGTLLFTYFRPSSSYSLDQDKMTSLFYTLVIPMLNPLIYSLRNKDVKEALGKMKRKR--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2JZC5-1", "uniprot_id": "A0A0G2JZC5_RAT", "id": "A0A0G2JZC5-1", "name": "Olfactory receptor", "aln": "MDIGNCS-LNEFIFVGVTNNPEMKGTLFTIFLLIYFINLLGNLGMIILIRMDPQLHTPMYFFLSHLSFCDLCYSTAIGPKMLVDMFGKNKSIPFWGCALQFFISCTFADSECVLLAVMAFDRYQAISNPLLYTVNMSSRVCSMLMAGVYLVGTSDALIHTTLAFRLCFCGSNEINHFFCDLPPLYLLSCSNTQVNELALFTVYGFLELSTISGVLVSYCYIIASVFKIRSTEGRLKAFSTCTSHLTAVAIFQGTLLFTYFRPSSSYSLDQDKMTSLFYTLVIPMLNPLIYSLRNKDVKEAMEKMKNKRCF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NH69-1", "uniprot_id": "OR5W2_HUMAN", "id": "Q8NH69-1", "name": "Olfactory receptor 5W2", "aln": "MDWENCSSLTDFFLLGITNNPEMKVTLFAVFLAVYIINFSANLGMIVLIRMDYQLHTPMYFFLSHLSFCDLCYSTATGPKMLVDLLAKNKSIPFYGCALQFLVFCIFADSECLLLSVMAFDRYKAIINPLLYTVNMSSRVCYLLLTGVYLVGIADALIHMTLAFRLCFCGSNEINHFFCDIPPLLLLSRSDTQVNELVLFTVFGFIELSTISGVFISYCYIILSVLEIHSAEGRFKALSTCTSHLSAVAIFQGTLLFMYFRPSSSYSLDQDKMTSLFYTLVVPMLNPLIYSLRNKDVKEALKKLKNKILF", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: *** *.:*:::*:******* ***::** :*:**: .*:***:***** *********************** *******::.*******:***:*::: * ******:**:*******:** ******.***** * ::::****** :***** ********************:**: *** *:**** *.***::**:********::****** **::*:*:***:**:*******:*********** ***********************:******************: *:*.* ", "identical_positions": 234, "similar_positions": 52, "identity": "75.48%" }, { "cls_id": "homologset.agr.MGI:1313139", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M660-1", "uniprot_id": "F1M660_RAT", "id": "F1M660-1", "name": "Olfactory receptor", "aln": "VVMEFTNGNYTLVTEFILLGFPTRPELQIILFLLFLMLYGMILIGNIGLMLLIRTDSHLQTPMYFFLSNLSFVDLCYSSVIVPNMLVNFLSSKKSISYLGCALQFYFFCTFADTESFILAAMAYDRYVAICNPLLYTVAMSKSLCTWLIVLSYVGGNMSSLVHTSFAFILKYCDKNIINHFFCDLPPLLKLSCTDTSINEWLLSTYGSSVEVICFFIIIISYFFILLSVLKIRSTSGRKKTFSTCASHLTSVAIYQGTLLFIYSRPSSLYSPNTDKIISVFYTIIIPVLNPLIYSLRNKDVKDAAKKALRSKIQSS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "G3X9L8-1", "uniprot_id": "G3X9L8_MOUSE", "id": "G3X9L8-1", "name": "Olfactory receptor", "aln": "MIMEFTSGNYTLVTEFILLGFPTRPELQIILFLVFLTLYGMILIGNIGLMLLIRMDPHLQTPMYFFLSNLSFVDLCYSSVIVPNMLVNFLSAKKSISYLGCALQFYFFCTFADTESFILAAMAYDRYVAICNPLLYTVAMSRSLCIWLIVLSYVGGNMSSLVHTSFAFILKYCDKNIINHFFCDLPPLLKLSCTDTSINEWLLSTYGSSVEIICFFIIIISYFFILLSVLKIRSTSGRKKTFSTCASHLTSVAIYQGTLLFIYSRPSSLYSPNTDKIISVFYTIIIPVLNPLIYSLRNKDVKDAAKKALRSKIQSP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13606-1", "uniprot_id": "OR5I1_HUMAN", "id": "Q13606-1", "name": "Olfactory receptor 5I1", "aln": "--MEFTDRNYTLVTEFILLGFPTRPELQIVLFLMFLTLYAIILIGNIGLMLLIRIDPHLQTPMYFFLSNLSFVDLCYFSDIVPKMLVNFLSENKSISYYGCALQFYFFCTFADTESFILAAMAYDRYVAICNPLLYTVVMSRGICMRLIVLSYLGGNMSSLVHTSFAFILKYCDKNVINHFFCDLPPLLKLSCTDTTINEWLLSTYGSSVEIICFIIIIISYFFILLSVLKIRSFSGRKKTFSTCASHLTSVTIYQGTLLFIYSRPSYLYSPNTDKIISVFYTIFIPVLNPLIYSLRNKDVKDAAEKVLRSKVDSS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ****. *********************:***:** **.:************* *.******************** * ***:******* :***** ***************************************.**:.:* ******:**********************:*******************:**************:***:****************** *****************:************** ****************:********************:*.****::*.", "identical_positions": 279, "similar_positions": 24, "identity": "88.29%" }, { "cls_id": "homologset.agr.MGI:1313140", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZYB3-1", "uniprot_id": "D3ZYB3_RAT", "id": "D3ZYB3-1", "name": "Olfactory receptor", "aln": "MEANNETQMHEFILLGLSGDWDTHVSLFILFLLMYLVTVLGNFLIILLIRLDSRLHTPMYFFLINLSLVDVPYATSIVPQLLAHFLAIHKAIPFLSCAAQLFFSLGLGGIEFLLLAVMAYDRYVAVCDPLRYSVIMHTGLCTWLAIASWVSGFINSLVHTVITFHLPMCA-KYIDHIACETLAVVRLACVDTSSNKIAIMVSSIVLLMTPFFLVLLSYIQIISTILKIQSTEGRWKAFHTCASHLTMVVLCYGMAIFTYIQPHSSPSVLQEKLMSLFYAILTPMLNPMIYSLRNKEVKGAWQKLLGKFSGFTSKLST", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VGP4-1", "uniprot_id": "Q8VGP4_MOUSE", "id": "Q8VGP4-1", "name": "Olfactory receptor", "aln": "METNNETQLHEFILLGLSSDWDSQVSLFVLFLLMYLVTVLGNFLIIVLIRLDSRLHTPMYFFLTNLSLVDASYATSIVPQLLAHFLATHKAIPFLSCAAQLFFSLGLGGIEFLLLAVMAYDRYVAVCDPLRYSVIMHAGLCTRLVITSWVSGSINSLVHTAITFQLPMCTNKYIDHIACETLAVVRLACVDTSSNKIAIMVSSIVLLMTPFFLVLLSYIQIISTILKIQSTEGRWKAFHTCASHLTMVVLCYGMAIFTYIQPHSSPSVLQEKLMSLFYAILTPMLNPMIYSLRNKEVKGAWQKLLGKFSGFASKLAT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13607-1", "uniprot_id": "OR2F1_HUMAN", "id": "Q13607-1", "name": "Olfactory receptor 2F1", "aln": "MGTDNQTWVSEFILLGLSSDWDTRVSLFVLFLVMYVVTVLGNCLIVLLIRLDSRLHTPMYFFLTNLSLVDVSYATSVVPQLLAHFLAEHKAIPFQSCAAQLFFSLALGGIEFVLLAVMAYDRYVAVCDALRYSAIMHGGLCARLAITSWVSGFISSPVQTAITFQLPMCRNKFIDHISCELLAVVRLACVDTSSNEVTIMVSSIVLLMTPFCLVLLSYIQIISTILKIQSREGRKKAFHTCASHLTVVALCYGVAIFTYIQPHSSPSVLQEKLFSVFYAILTPMLNPMIYSLRNKEVKGAWQKLLWKFSGLTSKLAT", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* ::*:* : ********.***::****:***:**:****** **::**************** ******..****:********** ****** **********.******:***************.****.*** ***: *.*:***** *.* *:*.***:**** *:****:** **************:::************* ****************** *** ***********:*.****:*******************:*:***************************** ****::***:*", "identical_positions": 260, "similar_positions": 39, "identity": "82.02%" }, { "cls_id": "homologset.agr.MGI:1313142", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LCF4-1", "uniprot_id": "A0ABK0LCF4_RAT", "id": "A0ABK0LCF4-1", "name": "Olfactory receptor", "aln": "MQRRETSGMGRENHTEVSQFLLLGLSD-DPKFQPILFGMFLFMYLITVLGNLLIILAVISDSHLHNPMYFFLSNLSFVDICFTTTTVPKMLVNIQTKNKNISYMQCLSQVYFFMVFAGMDNFLLTVMAFDRFVAICHPLNYTVIMNPHFCCLLVLMCWMIILSVSMFHSLLMKQLTFSMGTEIPHFFCELAQILRVTNSDVLINNIALYVATALLCVFPVTGILYSYSQIVSSLLKMSSVVSKYRAFSTCGSHLC-VVCLFYGTALGVYLSSAGTHVSQGS-TIASVMYTVVTPMLNPFIYSLRNKDVKGALVRFL-RVYSCPW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VG88-1", "uniprot_id": "Q8VG88_MOUSE", "id": "Q8VG88-1", "name": "Olfactory receptor", "aln": "--------MGKENHTELSQFLLLGLSD-DPKLQPILFGIFLFMYLVTVLGNLLIILAVSSDSHLHNPMYFFLSNLSFVDMCFTSTTVPKMLVNIQTKNKNISYMQCLTQVYFFMVFAGMDNFLLTVMAFDRFVAICHPLNYTVIMNPHFCCFLVLMCWIIILSVSLFHSLLMKQLTFSMGTEIPHFFCELAQILRVASSDILINNIALYVATALLCVFPVTGILFSYSQIVSSLLNMSSVVSKYRAFSTCGSHLC-VVCLFYGTALGVYLSSAGTDVSQGS-TIASVMYTVVTPMLNPFIYSLRNKDVKGALVRIL-KVYSCP-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NG98-1", "uniprot_id": "OR7D4_HUMAN", "id": "Q8NG98-1", "name": "Olfactory receptor 7D4", "aln": "--------MEAENLTELSKFLLLGLSD-DPELQPVLFGLFLSMYLVTVLGNLLIILAVSSDSHLHTPMYFFLSNLSFVDICFISTTVPKMLVSIQARSKDISYMGCLTQVYFLMMFAGMDTFLLAVMAYDRFVAICHPLHYTVIMNPCLCGLLVLASWFIIFWFSLVHILLMKRLTFSTGTEIPHFFCEPAQVLKVACSNTLLNNIVLYVATALLGVFPVAGILFSYSQIVSSLMGMSSTKGKYKAFSTCGSHLC-VVSLFYGTGLGVYLSSAVTHSSQSS-STASVMYAMVTPMLNPFIYSLRNKDVKGALERLLSRADSCP-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q2PRA8-1", "uniprot_id": "Q2PRA8_DANRE", "id": "Q2PRA8-1", "name": "Olfactory receptor", "aln": "----------MENISSSHILTVTALNDWDWTSRILFFSFALPGYLLTIILNATLIMIIAFEKALHEPMYIFLCNLCINDLCGITGFYPRALTYLLTERNVISHEECIVQGLVIVIYATGEFTSLSVMAVDRYIAICRPLHYHRIMSSFTVLSLVTFIWVFSCFVGLMAISLTLKYPICR-HNINKLFCEHLSLLNLACKHDIFEGIVNGFIFIIMSFLFVF-VLLSYLKIILACR--KSKVSREKFFSTCIPHLISFLNTTCGLSDSLYTKFNIDTLSHVEHTFLSIIILTVPPFLNPLIYGIKLGPIRAKILYIFQRPKIK--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** :. : : .*.* * : ::*.: * **:*:: * :*: : :. ** ***:**.**.: *:* : *: *. : :. : **: *: * .::::* : *:*** **::***:**:* **.. ** *.: ..:. * : .:. :* ::*** .:*.:: .. :::.*. . :: .: * :* ** :*: : .* .: : **** .** .: * . .:* . *: . : *:: *.*:***:**.:: ::. : :: : ", "identical_positions": 77, "similar_positions": 109, "identity": "23.77%" }, { "cls_id": "homologset.agr.MGI:1313258", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z0I6-1", "uniprot_id": "SLFN2_MOUSE", "id": "Q9Z0I6-1", "name": "Schlafen family member 2", "aln": "MGTRLEATEQSNHRTQRNDIQLENAKAAGKMGISVDLEAKYAKLGLNLGAITFGEKDRKKMKNSHLRKQENANISLAVCALLNSGGGAIKVKIENENYSLTRDGLGLDLEASLCKCLPFVQWHLDFTESEGYIYIYVKSWSQEIFGLPIGTLRTNLYVRSMSSSVQVSAAAALEFLQDLEETGGRPCVRPELPASIAFPEVEGEWHLEDLAAALFNRTEFQYEETFPFTRSRYVEVTLLSAKRLRKRIKELLPQTVSAFANTDGGFLFIGLDGKTQQIIGFEAEKSDLVLLESEIEKHIRQLPVTHFCEEKEKIKYTCKFIEVHKSGAVCAYVCALRVERFCCAVFAAEPESWHVEGGCVKRFTTEEWVKLQMNAPSG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A2D6-1", "uniprot_id": "D4A2D6_RAT", "id": "D4A2D6-1", "name": "", "aln": "------------------------------MGISVDLEAEYAKLGLNLGAITLGEKDRRKMKNSHLRKKENENISLAVCALLNSGGGAIKVKIENENYSLTRDGLGLDLETSLCKCLPFVQWYLDFTESKGYIYIYVRAWSQEIFGLPIGTLSTNLYVRVVSSSVQVSADAALQFLQDLEEAGGRPRVRPELPARKACPGVEGECHQEDLAAAFFNKTEFQYEETFFFTRSRYVEVTSLSVKRLRKRIREILPRTVSAFANTDGGYLFIGLDGKKQQIIGFEAEKSDLVHLESEIEKCIRQLPVTHFCEEREKIKYTCKFMEVHKPGAACSYVCALRVERFCCAVFAAEPESWHVEDSCVKRFAAEDWVRLQMGSREAWKR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8IYM2-1", "uniprot_id": "SLN12_HUMAN", "id": "Q8IYM2-1", "name": "Ribonuclease SLFN12", "aln": "------------------------------MNISVDLETNYAELVLDVGRVTLGENSRKKMKDCKLRKKQNESVSRAMCALLNSGGGVIKAEIENEDYSYTKDGIGLDLENSFSNILLFVPEYLDFMQNGNYFLIFVKSWSLNTSGLRITTLSSNLYKRDITSAKVMNATAALEFLKDMKKTRGRLYLRPELLAKRPCVDIQEENNMKALAGVFFDRTELDRKEKLTFTESTHVEIKNFSTEKLLQRIKEILPQYVSAFANTDGGYLFIGLN-EDKEIIGFKAEMSDLDDLEREIEKSIRKMPVHHFCMEKKKINYSCKFLGVYDKGSLCGYVCALRVERFCCAVFAKEPDSWHVKDNRVMQLTRKEWIQFMVEAEPKFSSSYEEVISQINTSLPAPHSWPLLEWQRQRHHCPGLSGRITYTPENLCRKLFLQHEGLKQLICEEMDSVRKGSLIFSRSWSVDLGLQENHKVLCDALLISQDSPPVLYTFHMVQDEEFKGYSTQTALTLKQKLAKIGGYTKKVCVMTKIFYLSPEGMTSCQYDLRSQVIYPESYYFTRRKYLLKALFKALKRLKSLRDQFSFAENLYQIIGIDCFQKNDKKMFKSCRRLT", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.******::**:* *::* :*:**:.*:***:.:***::* .:* *:*********.**.:****:** *:**:***** *:.: * ** :*** :. .*: *:*::** : ** * ** :*** * ::*: :.* ***:**:*:::: ** :**** * . :: * : : **..:*::**:: :*.: **.* :**:. :*.::* :**:*:**: **********:*****: : ::****:** *** ** **** **::** *** *::**:*:***: *:. *: *.**************** **:****:.. * ::: ::*::: : : ", "identical_positions": 176, "similar_positions": 108, "identity": "28.9%" }, { "cls_id": "homologset.agr.MGI:1313259", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z0I7-1", "uniprot_id": "SLFN1_MOUSE", "id": "Q9Z0I7-1", "name": "Schlafen family member 1", "aln": "MNITD--EGT-PVLILNAGGITLGTESRKTMEN-HDRVEENRNITKALCALINSGEGKVKAHIKNPDYILSKHGIGEDLETSFKNILPSRP--LDFKQYQSYFFICVEKSQSPDVSVGKPATIATNLYMRNGASSVEMNLDAAQKFLDNIKVAGGRSPS-ARP-SDRPGDDTQEEGHIQELAAAFFKQSKLTKKENFLFSESKNVEYKSFETKKLLQRVKEILPRTVSAFANTDGGYLFIGLDEKKQEIVGFEAKNCQPKCLESEIEKCIQQLPVTHFCEEREKIKYKCKFIEVHDSGVVCKYVCALRVERFCCAVFAAEPESWHMKDGGVKRFTIEEWIKLLMS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6GJB8-1", "uniprot_id": "A0A8I6GJB8_RAT", "id": "A0A8I6GJB8-1", "name": "", "aln": "MNITV--ETTKPALLLDAGEITLGIQSRKEMEN-HYRVKENRNILTALCALINFGEGKVKVQSKNPDYSLAKHGVGDDLETSFKNIWPSTP--LVFKQDQLNVFICVQ-PQSPDGSGGKPATIAINLFMRNGASSVEMSFDVAQEFLEKMAGAGGRSPL-ARLKGKRPGDGLQEEVHVQELAAAFFKQSKLTKMEKFPFSESKNVEYKSFETKKLLQRVKEILPRTVSAFANTDGGYLFIGLDEKEQQIVGFEAKNCHPKCLESEIEKCIRQLPVTHFCEEREKIKYTCKFMEVHKPGAVCSYVCALRVERFCCAVFAAEPDSWHVEDNHLKRFTTEEWVNQMIA-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8IYM2-1", "uniprot_id": "SLN12_HUMAN", "id": "Q8IYM2-1", "name": "Ribonuclease SLFN12", "aln": "MNISVDLETNYAELVLDVGRVTLGENSRKKMKDCKLRKKQNESVSRAMCALLNSGGGVIKAEIENEDYSYTKDGIGLDLENSFSNILLFVPEYLDFMQNGNYFLIFVK-SWSLNTSGLRITTLSSNLYKRDITSAKVMNATAALEFLKDMKKTRGRLYLRPELLAKRPCVDIQEENNMKALAGVFFDRTELDRKEKLTFTESTHVEIKNFSTEKLLQRIKEILPQYVSAFANTDGGYLFIGLNE-DKEIIGFKAEMSDLDDLEREIEKSIRKMPVHHFCMEKKKINYSCKFLGVYDKGSLCGYVCALRVERFCCAVFAKEPDSWHVKDNRVMQLTRKEWIQFMVEAEPKFSSSYEEVISQINTSLPAPHSWPLLEWQRQRHHCPGLSGRITYTPENLCRKLFLQHEGLKQLICEEMDSVRKGSLIFSRSWSVDLGLQENHKVLCDALLISQDSPPVLYTFHMVQDEEFKGYSTQTALTLKQKLAKIGGYTKKVCVMTKIFYLSPEGMTSCQYDLRSQVIYPESYYFTRRKYLLKALFKALKRLKSLRDQFSFAENLYQIIGIDCFQKNDKKMFKSCRRLT", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***: * . . *:*:.* :*** :*** *:: : * ::*..: *:***:* * * :*.. :* ** :*.*:* ***.**.** * * * * .:* *: . * : * : :*:: **: *: :*: *. .* :**..: : ** .. ..** . *** ::: **..**.:::* : *:: *:**.:** *.*.*:*****:*****: ****************:* .::*:**:*: .. . ** ****.*:::** *** *::**:*.***: *:. * :* **************** **:***::*. : ::* :**:: :: ", "identical_positions": 153, "similar_positions": 106, "identity": "26.38%" }, { "cls_id": "homologset.agr.MGI:1313266", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35112-1", "uniprot_id": "CD166_RAT", "id": "O35112-1", "name": "CD166 antigen", "aln": "MASKGSPSCRLVFCLLISAAVLRPGLGWYTVNSAYGDTIVMPCR--LDVPQNLMFGKWKYEKPDGSPVFIAFRSSTKKS-VQYDDVPEYKDRLSLSENYTLSINNAKISDEKRFVCMLVTEDNVFEAPTLVKVFKQPSKPEIVNRAAFLETEQLKKLGDCISRDSYPDGNITWYRNGKVLQPVDGEVSILFKKEIDPGTQLYTMTSSLEYKTTKSDIQMPFTCSVTYYGPSGQKTIYSEQAIFDIYYPTEQVTIQVLPPKNAIKEGDNITLQCLGNGNPPPEEFMFYLPGQAEGIRSSNTYTLTDVRRNATGDYKCSLIDQRNMAASTTITVHYLDLSLNPSGEVTKQIGDTLPVSCTISASRNATVVWMKDNIRLRSSPSFSSLHYQDAGNYVCETALQEVEGLKKRESLTLIVEGKPQIK-MTKKTDPSGLSKTIICHVEGFPKPAIQWTITGSGSVINQTEESPYINGRYYSKIIISPEENVTLTCTAENQLERTVNSLNVSAISIPEHDEADDISDENREKVNDQAKLIVGIVVGLLLAALVAGVVYWLYMKKSKTASKHVN-KDLGNMEENKKLEEN-NHKTEA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61490-1", "uniprot_id": "CD166_MOUSE", "id": "Q61490-1", "name": "CD166 antigen", "aln": "MASKVSPSCRLVFCLLISAAVLRPGLGWYTVNSAYGDTIVMPCR--LDVPQNLMFGKWKYEKPDGSPVFIAFRSSTKKS-VQYDDVPEYKDRLSLSENYTLSIANAKISDEKRFVCMLVTEDNVFEAPTLVKVFKQPSKPEIVNKAPFLETDQLKKLGDCISRDSYPDGNITWYRNGKVLQPVEGEVAILFKKEIDPGTQLYTVTSSLEYKTTRSDIQMPFTCSVTYYGPSGQKTIYSEQEIFDIYYPTEQVTIQVLPPKNAIKEGDNITLQCLGNGNPPPEEFMFYLPGQPEGIRSSNTYTLTDVRRNATGDYKCSLIDKRNMAASTTITVHYLDLSLNPSGEVTKQIGDTLPVSCTISASRNATVVWMKDNIRLRSSPSFSSLHYQDAGNYVCETALQEVEGLKKRESLTLIVEGKPQIK-MTKKTDPSGLSKTIICHVEGFPKPAIHWTITGSGSVINQTEESPYINGRYYSKIIISPEENVTLTCTAENQLERTVNSLNVSAISIPEHDEADDISDENREKVNDQAKLIVGIVVGLLLAALVAGVVYWLYMKKSKTASKHVN-KDLGNMEENKKLEEN-NHKTEA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13740-1", "uniprot_id": "CD166_HUMAN", "id": "Q13740-1", "name": "CD166 antigen", "aln": "MESKGASSCRLLFCLLISATVFRPGLGWYTVNSAYGDTIIIPCR--LDVPQNLMFGKWKYEKPDGSPVFIAFRSSTKKS-VQYDDVPEYKDRLNLSENYTLSISNARISDEKRFVCMLVTEDNVFEAPTIVKVFKQPSKPEIVSKALFLETEQLKKLGDCISEDSYPDGNITWYRNGKVLHPLEGAVVIIFKKEMDPVTQLYTMTSTLEYKTTKADIQMPFTCSVTYYGPSGQKTIHSEQAVFDIYYPTEQVTIQVLPPKNAIKEGDNITLKCLGNGNPPPEEFLFYLPGQPEGIRSSNTYTLTDVRRNATGDYKCSLIDKKSMIASTAITVHYLDLSLNPSGEVTRQIGDALPVSCTISASRNATVVWMKDNIRLRSSPSFSSLHYQDAGNYVCETALQEVEGLKKRESLTLIVEGKPQIK-MTKKTDPSGLSKTIICHVEGFPKPAIQWTITGSGSVINQTEESPYINGRYYSKIIISPEENVTLTCTAENQLERTVNSLNVSAISIPEHDEADEISDENREKVNDQAKLIVGIVVGLLLAALVAGVVYWLYMKKSKTASKHVN-KDLGNMEENKKLEEN-NHKTEA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q90460-1", "uniprot_id": "C166A_DANRE", "id": "Q90460-1", "name": "CD166 antigen homolog A", "aln": "-----MHSVICLFGAFIAAALFAPGSCLPTVIGLYGETIEVPCNNGNNKPDGLIFTKWKYAKDDGSPGDLLIKQAQKDDPTVSAMDG-YKTRVSIAANSSLLIAQGSLTDQRVFTCMVVSSTNLEEFSVEVKVHKKPSAPVIKNKVKELENGKLTQLGECVVESANPAADLIWMKNNQALVDDGKTIIITSDVTKDPVTGLSSTSSRLQYTARKEDVASQFTCVAKHVTGPNQ---VSTPDTFQIRYPTEKVSLQVVS-QSPIREGDDVTLKCQADGNPPPTSFNFNIKGKKVTVTDKDVYTLTGVTRADSGVYKCSLLDNDVMESTQIVTVSFLDASLTPTGKVLKKLGENLVVSLEKNASSEVKVTWTKDNRKLDKLPDFSQLRYSDAGLYVCDVS---IEGIKHSFSFELTVEGGPRITGLTKHRSNDGKHKVLTCEAEGSPKPEVQWSVNGTD------DETSYVNGKATYKLTVVPSKNLTVSCLVTNKLGFDTKDISVFSLFEEDKP-KPGKNEDG----ADQAKVIVGVVVGLFLAAALVGLIYWLYIKKTRQGSWKTGEKETGTSEESKKLEEN-NHKADV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1QE54-1", "uniprot_id": "F1QE54_DANRE", "id": "F1QE54-1", "name": "", "aln": "-----MQRTAFLT-CLLTVSLMNQVCGLETVTGKYGDTVEIPCNSGLVSDVGVTFVKWKSDKD----GSILVKHTGQN--ASSPTDGNYKNRVSIKKDFGLIITQVSLADQKTFTCMVVAADDILEYPVQLVIYKTPLQPQIANLTTAMEIGKLTTLAQCHTEGANPAANITWFKNKTPLIADGTAIKITNDVAVDKATGLSATTSKLEYTAVKDDINSKFTCQVQHIKSANM---DSSPLVFTVNYPSETISFHVLP-DGPVKEGDNVTLKCTADGNPPPSRYNFYIKGEKKTVEKSNIFILSNVTRQNTGEYKCSLVDNEILTASKNITVEYLDVILSTTGEVFKKLGDSFETTLDIKASGKTETFCKKGGEKMVGPPKFASLKYTDSGVYECVVT---MLGLKKTQTFDLNVHGQPLIKSLTKKRG-DGTNKILSCEAEGSPKPTVQWITNGTDVKF---QESEHVNGKITYYITVSPKANVTVSCTISNDLGSDTRSIDVSSLVEDVTMDKQDQSEDY----SDQTALAVGIVVGLMLAALLIGLAYWLYMKKFRQGSWKTGEKEDGSAEESKKLEENQSQKAEV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :::.::: ** . **:*: :**. .: * *** * : .: : :. . ** *:.: : * * : ::*:: *.**:*: :: * .. : :.* * * * . . :* :*. *.:* ..: * .:: * :* * : * . * * * : :* *:*.: : *: *** . : .. * * : **:* ::::*:. ...::***::**:* .:***** : * : *: : ..: : *:.* * :* *****:*: : :: :** :** *..:*:* :::*: : .: .** :. . *.. :: *.*:.*:* *:* * * .: : *:*: :: * *.* * *. :**: . .* * : *..** *** ::* .*:. :*: ::**: : : *. *:*::* *.* ...:.* :: .:: **: : **:****:*** : *: ****:** : .* :.. *: *. **.****** .:*::.", "identical_positions": 153, "similar_positions": 191, "identity": "25.98%" }, { "cls_id": "homologset.agr.MGI:1313268", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63148-1", "uniprot_id": "CHRD_RAT", "id": "Q63148-1", "name": "Chordin", "aln": "--------------------------------------------------MPSLPAPPAPRLLLGLLLLGSRPAGGTGPEAPALPIRSEKEPLPVR-GAAGCSFGGKVYALDETWHPDLGEPFGVMRCVLCACEAPQWARRGRGPGRVSCKNIKPQCPTLACRQPRQLPGHCCQTCPQDAERSNLDPQPAGLVFEYPRDPEHRSYSDRGEPGTGERTRGDGHTEDFVALLTG------PRTQAVARARVSLLRSSLRFSIS-YQRLDRPSRVRFTDPTGNILFEHPAAPTQD----------GLVCGVWRAVPRLSVRLLRAEQLRVALVTPTHPSEE--VWGPLIWQGALTAETFSAILTLE------DPLQRGVGGIALLTLS-DTEDALHFLLLFRGLL----GGLAHVPLKLQILHQGQLLRELQANAS--AQEPGFAEVLPSLTDQEMDWLVLGELQMVLEKMGGPELRISGYITTRQSCDVLQSVLCGADALIPVQTGAAGSASFILLGNGSLIYQVQVIGTGSEVVAMTLETKPQRKNQRTVLCHMAGLQLGGHMAVGVCSGLGARGAHMLLQNELFLNIGTKDFPDGELRGHVTALCYSGHSAHYDRLPVPLAGALVLPPVRSQAAGHAWLSLDTHCHLHYEVLLAGLGGSEQGTVTAHLLGPPGM-------PGPQRLLKGFYGSEAQGVVKDLEPVLLRHLTQGTASLLITTKSNPRGELRGQVHIASQCEVGGLRLASEGVRMSLAPNGEAATSPMLPAGPGPEAPVPAKHGSSGRPRDPNTCFFEGQQRPHGARWAPNYDPLCSLCTCQRRTVICDPVVCPPPSCPHPVQALD---QCCPVCPEKQRSRDLPSLP-NLEPGEGCYFDG-----DRSWRAAGTRWHPVVPPFGLIKCAVCTCKGATGEVHCEKVQCPRLACAQPVRANPTD--CCKQCPVG------------SGTHAKLGDPMQADGPR---------GCRFAGQWFPENQSWHPSVPPFGEMSCITCRCGAGVPHCERDDCSPPLSCGS-------------GKESRCCSHCTAQR--SSETRTLPELEKEAQRS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z0E2-1", "uniprot_id": "CHRD_MOUSE", "id": "Q9Z0E2-1", "name": "Chordin", "aln": "--------------------------------------------------MPSLPAPPAPRLLLGLLLLGSRPASGTGPEPPALPIRSEKEPLPVR-GAAGCSFGGKVYALDETWHPDLGEPFGVMRCVLCACEAPQWARRGRGPGRVSCKNIKPQCPTLACRQPRQLPGHCCQTCPQ--ERSNLDPQPAGLVFEYPRDPEHRSYSDRGEPGVGERTRADGHT-DFVALLTG------PRSQAVARARVSLLRSSLRFSVS-YQRLDRPSRVRFTDPTGNILFEHPATPTQD----------GLVCGVWRAVPRLSVRLLRAEQLRVALVTSTHPSGE--VWGPLIWQGALAAETFSAILTLE------DPLQRGVGGIALLTLS-DTEDSLHFLLLFRGLL----GGLAQAPLKLQILHQGQLLRELQANTS--AQEPGFAEVLPSLTDQEMDWLELGELQMVLEKAGGPELRISGYITTRQSCDVLQSVLCGADALIPVQTGAAGSASFILLGNGSLIYQVQVVGTGSEVVAMTLETKPQRKNQRTVLCHMAGLQPGGHMAVGMCSGLGARGAHMLLQNELFLNVGTKDFPDGELRGHVTALCYSGHSARYDRLPVPLAGALVLPPVRSQAAGHAWLSLDTHCHLHYEVLLAGLGGSEQGTVTAHLLGPPGM-------PGPQRLLKGFYGSEAQGVVKDLEPVLLRHLAQGTASLLITTKSSPRGELRGQVHIASQCEAGGLRLASEGVQMPLAPNGEAATSPMLPAGPGPEAPVPAKHGSPGRPRDPNTCFFEGQQRPHGARWAPNYDPLCSLCICQRRTVICDPVVCPPPSCPHPVQALD---QCCPVCPEKQRSRDLPSLP-NLEPGEGCYFDG-----DRSWRAAGTRWHPVVPPFGLIKCAVCTCKGATGEVHCEKVQCPRLACAQPVRANPTD--CCKQCPVG------------SGTNAKLGDPMQADGPR---------GCRFAGQWFPENQSWHPSVPPFGEMSCITCRCGAGVPHCERDDCSPPLSCGS-------------GKESRCCSHCTAQR--SSETRTLPELEKEAEHS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H2X0-1", "uniprot_id": "CHRD_HUMAN", "id": "Q9H2X0-1", "name": "Chordin", "aln": "--------------------------------------------------MPSLPAPPAPLLLLGLLLLGSRPARGAGPEPPVLPIRSEKEPLPVR-GAAGCTFGGKVYALDETWHPDLGEPFGVMRCVLCACEAPQWGRRTRGPGRVSCKNIKPECPTPACGQPRQLPGHCCQTCPQ--ERSSSERQPSGLSFEYPRDPEHRSYSDRGEPGAEERARGDGHT-DFVALLTG------PRSQAVARARVSLLRSSLRFSIS-YRRLDRPTRIRFSDSNGSVLFEHPAAPTQD----------GLVCGVWRAVPRLSLRLLRAEQLHVALVTLTHPSGE--VWGPLIRHRALAAETFSAILTLE------GPPQQGVGGITLLTLS-DTEDSLHFLLLFRGLLEPRSGGLTQVPLRLQILHQGQLLRELQANVS--AQEPGFAEVLPNLTVQEMDWLVLGELQMALEWAGRPGLRISGHIAARKSCDVLQSVLCGADALIPVQTGAAGSASLTLLGNGSLIYQVQVVGTSSEVVAMTLETKPQRRDQRTVLCHMAGLQPGGHTAVGICPGLGARGAHMLLQNELFLNVGTKDFPDGELRGHVAALPYCGHSARHDTLPVPLAGALVLPPVKSQAAGHAWLSLDTHCHLHYEVLLAGLGGSEQGTVTAHLLGPPGT-------PGPRRLLKGFYGSEAQGVVKDLEPELLRHLAKGMASLMITTKGSPRGELRGQVHIANQCEVGGLRLEAAGAEGVRALGAPDTASAAPPVVPGLPALAPAKPGGPGRPRDPNTCFFEGQQRPHGARWAPNYDPLCSLCTCQRRTVICDPVVCPPPSCPHPVQAPD---QCCPVCPEKQDVRDLPGLPRSRDPGEGCYFDG-----DRSWRAAGTRWHPVVPPFGLIKCAVCTCKGGTGEVHCEKVQCPRLACAQPVRVNPTD--CCKQCPVG------------SGAHPQLGDPMQADGPR---------GCRFAGQWFPESQSWHPSVPPFGEMSCITCRCGAGVPHCERDDCSLPLSCGS-------------GKESRCCSRCTAHRRPAPETRTDPELEKEAEGS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O57472-1", "uniprot_id": "CHRD_DANRE", "id": "O57472-1", "name": "Chordin", "aln": "---------------------------------------------------------MMEGLLWILLSVIIASVHGSRLKTPALPIQPEREPMISK-GLSGCSFGGRFYSLEDTWHPDLGEPFGVMHCVMCHCE-PQRSRRGKVFGKVSCRNMKQDCPDPTCDDPVLLPGHCCKTCPK-GDSGRKEVESLFDFFQEKDDDLHKSYNDRSYISSEDTSTRDSTTTDFVALLTGVTDSWLPSSSGVARARFTLSRTSLTFSIT-FQRINRPSLIAFLDTDGNTAFEFRVPQADN----------DMICGIWKNVPKPHMRQLEAEQLHVSMTTADNRKEE--LQGRIIKHRALFAETFSAILTS-------DEVHSGMGGIAMLTLS-DTENNLHFILIMQGLVP---PGSSKVPVRVKLQYRQHLLREIRANIT--ADDSDFAEVLADLNSRELFWLSRGQLQISVQTEGQTLRHISGFISGRRSCDTLQSVLSSGAALTAGQTGGVGSAVFTLHPNGSLDYQLLVAGLSSAVLSVSIEMKPRRRNKRSVLYELSAVFT-DQRAAGSCGRVEARHTHMLLQNELFINIATALQPDGELRGQIRLLPYNGLDARRNELPVPLAGVLVSPPVRTGAAGHAWVSVDPQCHLHYEIIVNGLSKSEDASISAHLHGLAEIGEMDDSSTNHKRLLTGFYGQQAQGVLKDISVELLRHLNEGTAYLQVSTKMNPRGEIRGRIHVPNHCES-------------PAPRAEFLEEPEFEDLLFTREPTELRKDT---HTHVHSCFFEGEQHTHGSQWTPQYN-TCFTCTCQKKTVICDPVMCPTLSCTHTVQPED---QCCPICEEKKESKETAAVEKVEENPEGCYFEG-----DQKMHAPGTTWHPFVPPFGYIKCAVCTCKGSTGEVHCEKVTCPPLTCSRPIRRNPSD--CCKECPPE------------ETPPLEDEEMMQADGTR---------LCKFGKNYYQNSEHWHPSVPLVGEMKCITCWCDHGVTKCQRKQC-PLLSCRNP-----------IRTEGKCCPECIEDFMEKEEMAKMAEKKKSWRH--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24025-1", "uniprot_id": "SOG_DROME", "id": "Q24025-1", "name": "Dorsal-ventral patterning protein Sog", "aln": "MANKLRKSNAIEWATATGTVPLLERSCCHSEDAALEPQASKTSHREQAPILRHLSQLSHLLIIAGLLIVCLAGVTEGRRHAPLMFEESDTGRRSNRPAVTECQFGKVLRELGSTWYADLGPPFGVMYCIKCECVAIPKKRR--IVARVQCRNIKNECPPAKCDDPISLPGKCCKTCPG--DRNDTDVALDVPVPNEEEERNMKHYAALLTGRTSYFLKGEEMKSMYTTYNPQ---------NVVATARFLFHKKNLYYSFYTSSRIGRPRAIQFVDDAGVILEEHQLETTLAGTLSVYQNATGKICGVWRRVPRDYKRILRDDRLHVVLLWGNKQQAELALAGKVAKYTALQTELFSSLLEAPLPDGKTDPQLAGAGGTAIVSTSSGAASSMHLTLVFNGVFGAEEYADAALSVKIELAERKEVIFDEIPRVRKPSAEINVLELSSPISIQNLRLMSRGKLLLTVESKKYPHLRIQGHIVTRASCEIFQTLLAPHSAESSTKS--SGLAWVYLNTDGSLAYNIETEHVNTRDRPNISLIEEQ--GKRKAKLEDLTPSFNFNQAIGSVEKLGPKVLESLYAGELGVNVATEHETSLIRG---RLVPRPVADARDSAEPILLKRQEHTDAQNPHAVGMAWMSIDNECNLHYEVTLNGVPAQDLQLYLEEKPIEAIG------APVTRKLLEEFNGSYLEGFFLSMPSAELIKLEMSVCYLEVHSKHSKQLLLRGKLKST------------------------KVPGHCFPVYTDNNVPVPGDHNDNHLVNGETKCFHSGRFYNESEQWR-SAQDSCQMCACLRGQSSCEVIKCPALKCKSTEQLLQRDGECCPSCVPKKEAADYSAQSSPATNATDLLQQRRGCRLGEQFHPAGASWHPFLPPNGFDTCTTCSCDPLTLEIRCPRLVCPPLQCSEKLAYRPDKKACCKICPEGKQSSSNGHKTTPNNPNVLQDQAMQRSPSHSAEEVLANGGCKVVNKVYENGQEWHPILMSHGEQKCIKCRCKDSKVNCDRKRCSRSTCQQQTRVTSKRRLFEKPDAAAPAIDECCSTQCRRSRRHHKRQPHHQQRSSS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: ** : . ..* : ..: : . : * ** . * .**:.*** ***** *: * * ** .:*.*:*:* :** * :* ***:**:*** : . : : : : * : . :.: . . ** **. : :..* :*. *:.** : * * * *. : . :**:*: **: * *. ::*:* : : . * : * : ** :* **::* . * ** :::: * .: . :*: *::.*:. . : .::::: : .:: : .. : : .. *: . :. ::: : *:* : :: . :*.*.* * **: :*::*. * . :: * * . * :*** *:: . .: . : : .:*.. . : * * : .: . * .** :*:.* .. : .*: . *: * . .. *.* **:*:* .*:****: : *: .: . . . ::** * *. :*.. .: * :* . . * : :* . : :**::: . . . .**..*. .. :* . : * * * : *: : **. .* . * : :*** * *: : .. . : ... :..*: ***.:** * .*:.*:*. * *::* :: ** * *:. : .* . *** ** . . : ** . .: *:. : : :.: *** : ** .**.* * . :*:*. * . . . . .* . : .:. . ", "identical_positions": 185, "similar_positions": 273, "identity": "16.99%" }, { "cls_id": "homologset.agr.MGI:1313269", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3Z9Z1-1", "uniprot_id": "D3Z9Z1_RAT", "id": "D3Z9Z1-1", "name": "Otoconin-90", "aln": "MATMIVLLMVSMLTIPCVGGHALDTPN-PQELPPGLSKNINITFFNGVFKNVESVTEIFDCLGSHFTWLQAVFTNFPLLLQFVNSMRCVAGLCPRDFEDYGCACRFEMEGLPLDESDSCCFQHRRCYEEAVEMDCLQDPAKLSADVDCISKQITCESEDPCERLLCTCDKAAVECLAQSGINSSLNFLDASFCLVQTPETTSGKAVT-PPPRGVPEKPTDTSQIAQSGEVAGERRADTLTTLSRTKSVQDLQDIQASRTTSSPGSAEIIAI---AKGTTHGSAGIKSVRLEVSSVDNSSRETTGKACGRLAFLHLGDGGSMKAMLHLGEMLFCLTSHCPEEFESYGCYCGREGRGVPRDTLDRCCLSHHCCLEQMRQLGCLHGRHSRSSVVCEHHTPKCVGQSLCEKLLCACDQMAAECMASAFFNQSLKSPDQPECQGEPVSCEDGMLGGTLASSVDSSSEENSEEAAPQMEPLRS-RLQEKPSGPLGIRTLGGR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z0L3-1", "uniprot_id": "OC90_MOUSE", "id": "Q9Z0L3-1", "name": "Otoconin-90", "aln": "---MIMLLMVGMLMAPCVGAHALDTPN-PQELPPGLSKNINITFFNGVFKNVESVAEIFDCLGSHFTWLQAVFTNFPLLLQFVNSMRCVTGLCPRDFEDYGCACRFEMEGMPVDESDICCFQHRRCYEEAVEMDCLQDPAKLSADVDCTNKQITCESEDPCERLLCTCDKAAVECLAQSGINSSLNFLDASFCLPQTPETTSGKAAT-LLPRGIPEKPTDTSQIALSGEVAGEVRADTLTTLSRTKSVQDLQDTQASRTTSSPGSAEIIAL---AKGTTH-SAGIKPLRLGVSSVDNGSQEAAGKACDRLAFVHLGDGDSMTAMLQLGEMLFCLTSHCPEEFETYGCYCGREGRGEPRDTLDRCCLSHHCCLEQMRQVGCLHGRRSQSSVVCEDHMAKCVGQSLCEKLLCACDQMAAECMASAFFNQSLKSPDGAECQGEPVSCEDGMLQGTLASSVDSSSEENSEEAPPQMERLR--RFLEKPPGPLGARPLGGK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q02509-1", "uniprot_id": "OC90_HUMAN", "id": "Q02509-1", "name": "Otoconin-90", "aln": "---MIAFLLTSVLMIPHAGGHPLDTPHLPQELPPGLPNNINITFFSGMFKNVESVAEIFDCLGPHFTWLQAVFTNFPVLIQFVNGMKCVAGLCPRDFEDYGCTCRFEMEGLPVDESDSCCFQHRRCYEEAAEMDCLQDPAKLSTEVNCVSKKIICESKDNCEHLLCTCDKAAIECLARSSLNSSLNLLDTSFCLAQTPETTIKEDLTTLLPRVVPVEPTDTSLTALSGEEAG----------------HDQEGVGAARATSPPGSAEIVATRVTAKIVTLVPAGIKSLGLAVSSVENDPEETTEKACDRFTFLHLGSGDNMQVMPQLGEMLFCLTSRCPEEFESYGCYCGQEGRGEPRDDLDRCCLSHHCCLEQVRRLGCLLERLPWSPVVCVDHTPKCGGQSLCEKLLCACDQTAAECMTSASFNQSLKSPSRLGCPGQPAACEDSLHPVPAAPTLGSSSEEDSEEDPPQEDLGRAKRFLRKSLGPLGIGPLHGR", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** :*:..:* * .*.*.****: ********.:*******.*:*******:*******.*************:*:****.*:**:************:*******:*:**** ************.************::*:* .*:* ***:* **:*********:****:*.:*****:**:**** ****** : * ** :* :***** * *** ** :* :. *:*:**.******:* ** .* .****.: * ****:*...*:: ***.*::*:***.*..* .* :**********:******:******:**** *** **************:*::*** * . *.*** .* .** ************** *****:** ********. * *:*.:***.: . *.::.*****:*** .** : * *: .*. **** .* *:", "identical_positions": 313, "similar_positions": 96, "identity": "63.1%" }, { "cls_id": "homologset.agr.MGI:1313271", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P57760-1", "uniprot_id": "STK16_RAT", "id": "P57760-1", "name": "Serine/threonine-protein kinase 16", "aln": "----------MGHALCVCSRGTVIIDNKRYLFVQKLGEGGFSYVDLVEG----------LHDGHFYALKRILCHEQQDQEEAQREADMHRLFQHPNILRLMAYSLKERG-----AKHEAWLLLPFFKRGTLWNEIERLKDQGNFLTEDQILPLLLGICRGLEAIHAKG----------------------------------------------YAHRDLKPTNILLGDEGQPVLMDLGSMNQACIQVEGSRQALALQDWAAQRCTISYRAPELFSVQSHCVIDERTDVWSLGCVLYAMMFGEGPYDMVFQK-GDSVALAVQN-DLSIPQSPRHSSALRQLLASMMTVDPQQRPHIPVLLSQLEALQPPAPGQHTTQI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88697-1", "uniprot_id": "STK16_MOUSE", "id": "O88697-1", "name": "Serine/threonine-protein kinase 16", "aln": "----------MGHALCVCSRGTVIIDNKRYLFVQKLGEGGFSYVDLVEG----------LHDGHFYALKRILCHEQQDQEEAQREAEMHRLFQHPNILRLMAYSLKERG-----AKHEAWLLLPFFKKGTLWNEIERLKDQGSFLTEDQILPLLLGISRGLEAIHAKG----------------------------------------------YAHRDLKPTNILLGDEGQPVLMDLGSMNQACIQVEGSRQALALQDWAAQRCTISYRAPELFSVQSHCVIDERTDVWSLGCVLYAMMFGEGPYDMVFQK-GDSVALAVQN-ELSIPQSPRHSSALRQLLSSMMTVDPQQRPHIPVLLSQLEALQPPAPGQHTTQI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75716-1", "uniprot_id": "STK16_HUMAN", "id": "O75716-1", "name": "Serine/threonine-protein kinase 16", "aln": "----------MGHALCVCSRGTVIIDNKRYLFIQKLGEGGFSYVDLVEG----------LHDGHFYALKRILCHEQQDREEAQREADMHRLFNHPNILRLVAYCLRERG-----AKHEAWLLLPFFKRGTLWNEIERLKDKGNFLTEDQILWLLLGICRGLEAIHAKG----------------------------------------------YAHRDLKPTNILLGDEGQPVLMDLGSMNQACIHVEGSRQALTLQDWAAQRCTISYRAPELFSVQSHCVIDERTDVWSLGCVLYAMMFGEGPYDMVFQK-GDSVALAVQN-QLSIPQSPRHSSALRQLLNSMMTVDPHQRPHIPLLLSQLEALQPPAPGQHTTQI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VI84-1", "uniprot_id": "Q9VI84_DROME", "id": "Q9VI84-1", "name": "non-specific serine/threonine protein kinase", "aln": "MQSIGWTLIMKRGCLFSCRKETLNINGSRYTIRERLATGGFSLIDLGEN----------ASTRRSYAIKRITCHSIDDQNIALREIENCRKIDSENVIRVVDYELKGQADIVINTTSTLFIVLPYYKHGSLADHLQLRSRKQDHMPEAQILQIFLGVCEGLKAIHEAMP-------------------------------------------VPLAHRDLKTANICLSDSFEPIIVDLGSMTEARLQIVGQTDAQRLQDEAEERSSIVYRAPELFTVKTYCTIDERTDIWSLGCVLYAMCYFNSPYDPIYER-GDSVALAVLSGNINIPEDSIYTEDMHELIKYMLRTDPMERPFVFSVIERTHDLIQKLEGRL----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12003-1", "uniprot_id": "ENV7_YEAST", "id": "Q12003-1", "name": "Serine/threonine-protein kinase ENV7", "aln": "MISIVLELFQNLCCCRGFSDATIRVNDKRYRIQRLLGEGGMSFVYLVQLSKNSLIIDNGIATPELYALKKIICPSVESISNGMREIENYKRFQSPYVIKSIDSQVMQEKD----GSKTIYIVLPYYSLGSLQDSINRRLLEGTFVSEAECVRIMLGVTRGLLCLHDPASRQDNATSRVNVDAVSMTYSDETAMLLEDTPLEMDMLSSNSAGSIAYAHRDITPSNILFSSDGLPVIGDLGSCSQADITIENRHQLSELQEWVNDNCTLPYTPPELLNLKLNQVLSSKVDIWSLGCTFYTLMFGISPFEREEQIHGASLTYAINTGKYSFPRNSRFSEGLLSVIKKCIQVDPIQRPTTSQLLNLLQDLDT----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *: ::..** : . *. **:* : * : . **:*:* * . :. . . ** : : :: ::: : : . . :::**::. *:* : :: : .:.* : : ::**: .** .:* ****:..:** :... *:: **** .:* : : . : **: . :..:: * .***:.:: .:..:.*:*****.:*:: : .*:: : * *:: *: . . .:*... .:. : .:: : .** :** ::. . * ", "identical_positions": 60, "similar_positions": 121, "identity": "15.87%" }, { "cls_id": "homologset.agr.MGI:1313274", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A1B0GWT2-1", "uniprot_id": "A0A1B0GWT2_RAT", "id": "A0A1B0GWT2-1", "name": "ubiquitinyl hydrolase 1", "aln": "----------------------------MTVTTRGSPVGENESQGQAPDGQSQPSFQQNQNS---------PATPP-DEQGQGDAPPQHEEED-----------PTFPHADLAKLEDMINRPRWVVPVLPKGELEVLLEASIDLTKKGIDAKSEACQRFFRDVLTVSFTKILTDEAVSGWKFEIHRCIINNTHRLMELCVAKLSQDWFPFLELLAIALNPHCKFHVYNGARPCESVSSS----VQFPEDELFACSP-DLRSPKGWLVDLINTFGTLNGFQILHDRFISG----------------------------SALNVQTIAALIKPFGQCCEYLTQHTLKKYFIPVIEVVPQLLQKLTNEELKKEAKTEVKNDAISMIIKFLKNLASRIPGQEETVKNLEIFRLKMILRLLQISSFNGKMNALNEINKVLSSVSYYTHR-----HGNSEEE--WLTAERMAEWIQQNNILSIVLQDSLHQPQYVEKLEKILRFVIKEKALTLQDLNNIWAAQAGKHEAIVKNVHDLLAKLAWDFSPEQLDHLFDCFKASWTNASKKQREKLLELIRRLAEDDKDGVMAQKVLNLLWNLAHSDDVPVDIMDLALSAHIKILDYSCSQDRDTQKIQWIDCFIEEFRTNNKWVIPALKQIKEICSLFGEAPQNLSQTHRSPHVFYRHDLISQLQHNHALVTLVAENLATYMNSIRLYARDHEDYDPQTIRLGSRYSHVQEVQERLNFLRFLLKDGQLWLCASQAKQIWHCLAENAVYFSDREACFMWYSKLMGDEPDLDPDINKEFFESNVLQLDPSLLTENGIKCFERFFKTVNCREGKLMIKRKVYMMDDLDLIGLDYLWKVVIQSNDDISNRAIDLLKEIYTSLGPRLQANQVVIHEDFIQSCFDRMKSSYDTLHVLD-----------------SDKDNIFSCARQEAIRIVRILTVLREYISECDSDYHEERMILPMSRAFRGKHLSLTVRFPNQSKEVDDLDILSHTNATIGSVRRCILNRIN-ANVTHTKIELFIG-GELIDSEDDRKLVEQLNLKDKSLITAKFLQINSNMPSSPDSSSDSSAGSPGNHCHNNYRDVPNSEMENCLPGVIMSLQPRYVSFLWQVADLGSMLTMPTLRDGARILMKLMPPDNTTIENLRAVC--------------------------SDHLNLGERRLGQSLHSLFFGSSASKVLYLTEVVYILLMPAGAHLADISSDFQYHFLKNGGLPLVLSMLIQNNFLPNTDVETRRDAYFSALKIAKLLLTTIG--YGHVQAIAEACQPVADGTDPKTPINQATHDQAVVLQNALQSIPNPSSECMLRNVS--IRLAHQISG----LASRYIPDICVIRAIQKIIWTSGCGSLELVFSPHEDITKTYKMTTSTRSNPEVKDEQVCCEALEVMTLCFALIPTALDSLSKEKAWQSFVIDLLLYCPSKTIRQLAQEQFFLICTRCCMGHRPLLFFITLLFTILGSAATEKGKHSDVYFPLLRRLLTYAYNSNIHIPNVDVLLNDEINWLKRVRDYIKNTGETSVEDPILEGHLGVTKELLSFQTPDKKYHIGCKAGGANLVKELIDDFIFPASKAYLQYSRSGEMPNKQTIP-VCGSPATVNAGFELLVALAFGCVRNLKQIVNCLTEMFYIGTPVN---TLAEWEYLPPVGPRPPKGFVGLKNAGATCYMNSVIQQLYMIPSIRNSILAIENIWNDTDDDTFKDERQD-----SENNIDPRDDVFGYPHQFEDKPTLNKAEDRKDYNIGVLKHLQITFGHLAASQLQYYVPRGFWQQFRLWGEPVNLREQHDALEFFNSLVDSLDEAFKALGHPTLLSKVLGGSFADQKICQGCPHRYECEESFTTLNVDIRNHQNLLDSLEQYIKGDLLEGANAYHCEKCDKKVDTVKRLLIKKLPSVLAIQLKRFDYDWERECAIKFNDYFEFPRELDMEPYTVAGATKLEGDGVHPQTQ--LIKQNEQSENVVPGSTKYRLVGVLVHSGQANGGHYYSYIIQRNGK--DNNRGRWFKFDDGDVTECKMDDDEEMKNQCFGGEYMGEVFDHMMKRMSYRRQKRWWNAYILFYERMDITDEDNEMITYLSELTIT-RPHQ-IMSPAIERSVWKQNVQFLHNQMQFSLEYFQFIKKLLTCNAVYLNPAPGQDHLPPEAEDITMISIQLAARFLFTTGFHTKKIVRGPANDWYDALCILLRHSKNVRFWFAHNVLFNVSNRFSEYLLECPSAEVRGTFAKLIVFIAHFSLQDGSSSS-FASPFATPGPYSQIYDNLSLSDHLLKAVLSLLRREVSEHGRHLQQYFNLFIMYASLGLAEKTQLLKLNVPTTFMLVSLDEGPGPPIKYQYAELGKLHSVVSQLIRCCSVSSRMQSSINGNPPLPNPFGDPNLS-QPIMPIQQNVADILFMRTTYVKKIIEDCSNSEETVKLLRFCCWENPQFSCSVLSELLWQVAYSYAYELQPYLDLLLQIILLEDSWQAHRIHNALKGIPSDRDGLFDTIQHFKNHHQKRAYQCIKWMVTLFNSCPVAYQILQGNGDLKKKWTWAVEWLGDELERKPYSGNPHYTYSNWSPPIQSNETANGYFLERSHSARMTLAKACDLCPEEDTDDQDAPDEHESPA---------------------------PQERTFYLYSH----------------------------RSQYQQS-YVPEQPYSGLTEHHLNEPQKN-DEPQE------------------------------THESSEEESSSLIKDQ-------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F8VPU6-1", "uniprot_id": "USP9Y_MOUSE", "id": "F8VPU6-1", "name": "Ubiquitin carboxyl-terminal hydrolase 9Y", "aln": "----------------------------MTITTRGSPVGENESQGQTSDGQPQPSFQQNQISSSDSSNETSPTTPP-YEQGQGDAPPQHEEED-----------PSFPHTDLAKLEDMINRSRWVVPVLPKGELEVLLEASIDLTKKGLDVKSEACQRFFRDVLTVSFSKILMDEAVSGWKFEIHRCIINNTHRLVELCVAKLSQDWFPFLELLAIALNPHCKFHVYNGARPCESVSSS----VQFPEDELFACSP-DLHSPKGWLVDLINTFGTLNGFQILHDRFTSG----------------------------SALNVQTIAALIKPFGQCYEFLTQHTLRKYFIPVIEVVPQILQKLTNEELKKETKTEVKNDTISMIIKFLKNLASRIPGQEETVKNLETFRLKMILRLLQISSFNGKMNALNEINKVLSSVSYYTHG-----HGNSEEE--WLTVERMTEWIQQNNILSIVLQDSLHQPQYVEKIEKILRFVIKEKALTLQDLNNIWAAQAGKHEAIVKNVHDLLAKLAWNFSPEQLDHLFDCFKASWTNASKKQREKLLELIRRLAEDDKDGVMAHKVLNLLWNLAHSDDVPVDIMDLALSAHIKILDYSCSQDRDTQKIQWIDCFIEEFRTNNKWVIPALKQIKEICSLFGEAPQNLSQTHQSPRVFYRHDLISQLQHNHALVTLVAENLAAYMNSIRLYARDHEDYDPQTVRLGSRYSHVQEVQERLNFLRFLLKDGQLWLCVSQAKQIWNCLAENAVYFSDREACFMWYSKLMGDEPDLHPDINKEFFESNVLQLDPSLLTENGMKCFERFFKTVNCREGKLMIKRKIYMMDDLDLIGLDYLWKVVIQSNDDISSRAIDLLKEIYTSLGPKLQANQVVIHEDFIQSCFDRLKASYDTLCVLD-----------------SEKDNIFSCARQEAIRMVRILTVLREYISEYDSDYHEERMILPMSRAFRGKHLSFTVRFPNQGKEVEDLDILSHTNATIGSVRRCILNRMN-VNVAHTKIELFIG-GELVASEDDRKLVEQLNLKDKSLITAKFIQINSNMPSSPDSSSDSSAGPPGNHSHNNYRDVSNPEMEKCLPGVIMSLQPRYISFLWQVADLGSMLTVPTLRDGARILMKLMPPDSTTLEQLRALC--------------------------SDHVNLGERRLGQSLHSLFFGSSASQVLYLTEVVYTLLMPAGAPLADISSDFQYHFLKSGGLPLVLSMLIQNNFLPNTDVETRRDAYFSALKIAKLLLTIVG--YGHVQAIAEACQPVADGTDPKTPINQVTHDQAVVLQNALQSIPNPSSECMLRNVS--VHLAQQISG----LASRYIPDICVIRAIQKIIWAAGCGSLELVFSPNEDITETYKMTTSTRSNLEVKDEQVCCEALEVMTLCFALIPTAMDSLNKEKAWQSFVIDLLLYCPSKTVRQLAQEQFFLICTRCCMGHRPLLFFITLLFTILGGAANEKGKHSDVYFTLLRRLLTYAYNSNIQVPNVDVLLNDEIDWLKRVRDYIKNTGETNVEDPILEGHLGVTKELLSFQSPEKKYHIGCKTGGANLVKELIDYFIFPASKAYLQYMRSGELPIKQAIP-VCGSPATINAGFELLVALAFGCVRNLKQIVNCLTELFYIGTPVTTCEAVGEWEYLPPVGPRPPKGFVGLKNAGATCYMNSVIQQLYMIPSIRNSILAIDSIWSDTDDDIFKGEKQD-----SENNVDPRDDVFRYPHQFEDKPTLSKVEDRKEYNIAVLKHLQITFGHLAASQLQYYVPKGFWQQFRLWGEPVNLREQHDALEFFNSLVDSLDEAFKALGYPTVLSKVLGGSFADQKICQGCPHRYECEESFTTLNVDIRNHQNLLDSLEQYVKGDLLEGANAYHCEKCDKKVDTVKRLLIKKLPSVLTIQLKRFDYDWERECAIKFNDYFEFPRELDMEPYTVAGATKLEGDSVNPQTQ--LIKQNEQSESVIPGSTKYRLVGVLVHSGQANGGHYYSYIIQRNGK--DSKRSHWFKFDDGDVTECKMDDDEEMKNQCFGGEYMGEVFDHMMKRMSYRRQKRWWNAYILFYERMDITDEDDEIITYISELTFT-RPHQ-IMSPAIERSVWKQNVQFLHNQMQFSLEYFQFIKKLLTCNAVYLSPAPGQDHLLPEAEDITMISIQLASRFLFTTGFHTKKIIRGPANDWYDALCILLRHSKNVRFWFVHNVLFNVSNRFSEYLLECPSAEIRGTFAKLIVFIAHFSLQDGSSPSPFTSPFANPGPYSQIYDNLSLSDHLLKAVLSLLRREVSEHGRHLQQYFNLFIMYASLGLAEKTQLLKLNVPATFMLVSLDEGPGPPVKYQYAELSKLHSVVSQLIRCCSVSSRMQSSINGNPPLPNPFGDPNLS-QPIMPIQQNVADILFMRTTYMKKVIEDCSNSEDTVKLLLFCCWENPQFSCSVLSELLWQVAHSHAYELQPYLDLLLQIILFEDSWQAHRIHNALKGIPNDQDGLFDTIQHSKNHHQKRAYQCIKWMVTLFNSCPVAYQILQGNGDLKNKWTWAMEWLGDELERKPYSGNPQYTYSNWSPPVQSNETANGYFLEKSHSAKMKLTKACDLYPEEDPDDQDALDEHVSHA---------------------------PQDRTFYLYSH----------------------------RSHYQQN-YVPEQPFSGPASHHLNNPQKN-DKPQE------------------------------THESNEEISSCLIKDQ-------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00507-1", "uniprot_id": "USP9Y_HUMAN", "id": "O00507-1", "name": "Ubiquitin carboxyl-terminal hydrolase 9Y", "aln": "----------------------------MTAITHGSPVGGNDSQGQVLDGQSQHLFQQNQTSSPDSSNENSVATPPPEEQGQGDAPPQHEDEE-----------PAFPHTELANLDDMINRPRWVVPVLPKGELEVLLEAAIDLSVKGLDVKSEACQRFFRDGLTISFTKILMDEAVSGWKFEIHRCIINNTHRLVELCVAKLSQDWFPLLELLAMALNPHCKFHIYNGTRPCELISSN----AQLPEDELFARSS-DPRSPKGWLVDLINKFGTLNGFQILHDRFFNG----------------------------SALNIQIIAALIKPFGQCYEFLSQHTLKKYFIPVIEIVPHLLENLTDEELKKEAKNEAKNDALSMIIKSLKNLASRISGQDETIKNLEIFRLKMILRLLQISSFNGKMNALNEINKVISSVSYYTHR-----HSNPEEEE-WLTAERMAEWIQQNNILSIVLQDSLHQPQYVEKLEKILRFVIKEKALTLQDLDNIWAAQAGKHEAIVKNVHDLLAKLAWDFSPGQLDHLFDCFKASWTNASKKQREKLLELIRRLAEDDKDGVMAHKVLNLLWNLAQSDDVPVDIMDLALSAHIKILDYSCSQDRDAQKIQWIDHFIEELRTNDKWVIPALKQIREICSLFGEASQNLSQTQRSPHIFYRHDLINQLQQNHALVTLVAENLATYMNSIRLYAGDHEDYDPQTVRLGSRYSHVQEVQERLNFLRFLLKDGQLWLCAPQAKQIWKCLAENAVYLCDREACFKWYSKLMGDEPDLDPDINKDFFESNVLQLDPSLLTENGMKCFERFFKAVNCRERKLIAKRRSYMMDDLELIGLDYLWRVVIQSSDEIANRAIDLLKEIYTNLGPRLKANQVVIHEDFIQSCFDRLKASYDTLCVFD-----------------GDKNSIN-CARQEAIRMVRVLTVIKEYINECDSDYHKERMILPMSRAFRGKHLSLIVRFPNQGRQVDELDIWSHTNDTIGSVRRCIVNRIK-ANVAHKKIELFVG-GELIDSEDDRKLIGQLNLKDKSLITAKLTQINFNMPSSPDSSSDSSTASPGNHRN-HYNDGPNLEVESCLPGVIMSVHPRYISFLWQVADLGSNLNMPPLRDGARVLMKLMPPDRTAVEKLRAVC--------------------------LDHAKLGEGKLSPPLDSLFFGPSASQVLYLTEVVYALLMPAGVPLTDGSSDFQVHFLKSGGLPLVLSMLIRNNFLPNTDMETRRGAYLNALKIAKLLLTAIG--YGHVRAVAEACQPVVDGTDPITQINQVTHDQAVVLQSALQSIPNPSSECVLRNES--ILLAQEISN----EASRYMPDICVIRAIQKIIWASACGALGLVFSPNEEITKIYQMTTNGSNKLEVEDEQVCCEALEVMTLCFALLPTALDALSKEKAWQTFIIDLLLHCPSKTVRQLAQEQFFLMCTRCCMGHRPLLFFITLLFTILGSTAREKGKYSGDYFTLLRHLLNYAYNGNINIPNAEVLLVSEIDWLKRIRDNVKNTGETGVEEPILEGHLGVTKELLAFQTSEKKYHFGCEKGGANLIKELIDDFIFPASKVYLQYLRSGELPAEQAIP-VCSSPVTINAGFELLVALAIGCVRNLKQIVDCLTEMYYMGTAITTCEALTEWEYLPPVGPRPPKGFVGLKNAGATCYMNSVIQQLYMIPSIRNSILAIEGTGSDLHDDMFGDEKQD-----SESNVDPRDDVFGYPHQFEDKPALSKTEDRKEYNIGVLRHLQVIFGHLAASQLQYYVPRGFWKQFRLWGEPVNLREQHDALEFFNSLVDSLDEALKALGHPAILSKVLGGSFADQKICQGCPHRYECEESFTTLNVDIRNHQNLLDSLEQYIKGDLLEGANAYHCEKCDKKVDTVKRLLIKKLPRVLAIQLKRFDYDWERECAIKFNDYFEFPRELDMGPYTVAGVANLERDNVNSENE--LIEQKEQSDNETAGGTKYRLVGVLVHSGQASGGHYYSYIIQRNGK--DDQTDHWYKFDDGDVTECKMDDDEEMKNQCFGGEYMGEVFDHMMKRMSYRRQKRWWNAYILFYEQMDMIDEDDEMIRYISELTIA-RPHQIIMSPAIERSVRKQNVKFMHNRLQYSLEYFQFVKKLLTCNGVYLNPAPGQDYLLPEAEEITMISIQLAARFLFTTGFHTKKIVRGPASDWYDALCVLLRHSKNVRFWFTHNVLFNVSNRFSEYLLECPSAEVRGAFAKLIVFIAHFSLQDGSCPS----PFASPGPSSQACDNLSLSDHLLRATLNLLRREVSEHGHHLQQYFNLFVMYANLGVAEKTQLLKLNVPATFMLVSLDEGPGPPIKYQYAELGKLYSVVSQLIRCCNVSSTMQSSINGNPPLPNPFGDLNLS-QPIMPIQQNVLDILFVRTSYVKKIIEDCSNSEDTIKLLRFCSWENPQFSSTVLSELLWQVAYSYTYELRPYLDLLFQILLIEDSWQTHRIHNALKGIPDDRDGLFDTIQRSKNHYQKRAYQCIKCMVALFSSCPVAYQILQGNGDLKRKWTWAVEWLGDELERRPYTGNPQYSYNNWSPPVQSNETANGYFLERSHSARMTLAKACELCPEEEPDDQDAPDEHEPSP---------------------------SEDAPLYPHSP----------------------------ASQYQQNNHVHGQPYTGPAAHHLNNPQKTGQRTQE------------------------------NYEGNEEVSSPQMKDQ-------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AW48-1", "uniprot_id": "A0A8M3AW48_DANRE", "id": "A0A8M3AW48-1", "name": "ubiquitinyl hydrolase 1", "aln": "----------------------------MTATTRGSPVGGNDGQGQAPDGQSQPPLPQNQTSSPNSSNENSPVSPP-DDQGQGDSPTPLEEEE-----------PAFPHTELAKLDDMINRPRWVVPVLPKGELEVLLEAAIDLCKKGIDVKCEACQRFFRDGLTISFTKILTDEAVSGWKFEIHRCIINNAHRLVELCVTKLSQDWFPLLELLAMATNPHCKFHIYNGTRPSETVPAG----VQLAEDELFARPP-DPRSPKGWLVDLINKFGTLNGFQTLHDRFMSG----------------------------QALNVQIIAALIKPFGQCYEFLTLHTVKKYFLPIIEMVPQFLENLTDEELKKEAKNEAKNDALSMIIKSLKNLASRVPGQEETVKNLEIFRLKMILRLLQISSFNGKMNALNEVNKVISSVSYYTHR-----HGNPEEEE-WLTAERMAEWIQQNNILSIVLRDSLHQPQYVEKLEKILRFVIKEKALTLQDLDNIWAAQAGKHEAIVKNVHDLLAKLAWDFSPEQLDHLFDCFKESWTNASKKQREKLLELIRRLAEDDKDGVMAHKVLNLLWNLAHSDDVPVDIMDQALSAHIKILDYSCSQDRDTQKMQWIDRFIEELRTNDKWVIPALKQIREICSLFGEAPQNLSQTQRSPHVFYRHDLINQLQHNHALVTLVAENLSAYMENMRQFSKEHADFDPQTVRPGSRYSHVQEVQERLNFLRFLLKDGQLWLCAPQAKQIWKCLAENAVFLCDREACFKWYSKLMGDEPDLDPDINKDFFENNVLQLDPSLLTENGMKCFERFFKAVNCREGKLVAKRRAYMMDDLELIGLDYLWRVVIQGSDDIASRAIDLLKEIYTNLGPKLQANQVEIHEDFIQSCFDRLKASYDTLCVLD-----------------GDKDSIN-CARQEAIRMVRVLTVLREYITECDSDYHEERTILPMSRAFRGKHITLVVRFPNQGRQVDDLDIWSHTNDTIGSVRRCILNRIK-ANSTHTKIELFIG-GEIIDPADDRKLIGQLNLKDKTLITAKLTQVSANMPSSPDSSSDSSTGSPGNHGN-HYSDGPNPEVESCLPGVIMSLHVRYISFLWQVADLGCNLNMPLLRDGARVLMKLMPPDNATVENLRAIC--------------------------LDHAKLGENSLSPTLDSRFFGPSPSQVLYLIEVVYALLMPASGTLGEDASDFQYNFLKSGGLPLVLSMLTRNNFLPNADMETRRGAYLNALKIAKLLLTAVG--FGHVKSVAEACQPVVEGTIPVSPINQTTHDQALVLQNALQNIPNPSAECMLRNVA--IRLAQQISDENFFQASKYIPDICVIRAVQKIVWASGCGSVQHVFSSNEEISKIYEKTNAG-NEPDAEDEQVCCEALEVMTLCFALMPTALDALSKEKAWQTFIIDLLLHCQSKSVRQMAQEQFFLMATRCCMGHRPLLFFITLLFTVLGSTAKERAKHAADYFTLLRHLLNYAFNSNINLPNAEVLLNNEIDWLKRIRDEVKRTGEPGVEETILEGHIGVTKELLAFQTPEKKFYIGCEKGGASLIKELMDDFLFPASNVYLQYMKSGEFPTEQAIP-VCSTPATINAGFELLVALAIGCVRNLKQIVDTLTDMYYLG-----CEPLTEWEYLPPVGPRPTKGFVGLKNAGATCYMNSVIQQLYMIPPIRNGILAIEGTGSDVDDDMSGDEKQD-----NESNVDPRDEVFGYQHQFDDKPSLSKSEDRKEYNIGVLRQLQVIFGHLASSRLQYYVPRGFWKQFRLWGEPVNLREQHDALEFFNSLVDSLDEALKALGHPAMLSKVLGGSFADQKICQGCPHRYECEESFTTLNVDIRNHQNLLDSMEQYVKGDLLEGANAYHCEKCNKKVDTVKRLLIKKLPPVLAIQLKRFDYDWERECAIKFNDYFEFPRELDMEPYTVAGVAKLEGSDVHPENQQQVIQQNEPSEPEPPCSSRYRLVGVLVHSGQASGGHYYSYIIQRNGSGGEGERNRWYKFDDGDVTECKMDDDEEMKNQCFGGEYMGEVFDHMMKRMSYRRQKRWWNAYILFYERMDTLDKDSELVKYITELTVSSKPHQVKMPSAIERSVRKQNVQFMHNRMQYSLEYFQFIRKLLTCNSVYLNSPPGQDHLLPEAEEMAMISIQLAARFLFSTGFHTKKIVRGPASDWYDALCILLRHSKNVRYWFAHNVLFAYPNRFSEYLLECPSAEVRGAFSKLIVFIAHFSLQDGPCPT----PIASPGPSSQGCDNLSLSEHLFRAVLNLLRREVSEHGRHLQQYFNLFVMYANLGLAEKTQLLKLGVPATFMLVALDEGPGPPIKYQYAELGKLYTVVSQLVRCCDVTSRMQSSINGNPPLANPYGDPNTT-TPIMPLQQLVVDILFVRTSYVKKIIEDCSNSEDTIKLLRFCCWENPQFSSTVLSELLWQVAYSYTYELRPYLDLLLQILFIEDSWQTHRIHNVLKGIPDDRDGLFDTIQRSKNHYQKRAYQCIKCMVALFSNCSVAYQILQSNGDLKRKWTWAVEWLGDELERRPYTGNTQYTYNNWSPPVQSNETSNGYFLERSHSARMTLAKACELCPEEEPDEQEALDEQDPSP---------------------------PEDTALYPHSP----------------------------GSKFQQNNLPHTQPYTGPAAQHVNNPQRPGPRAQE------------------------------NWEPPEETPQPSQTKD-------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P55824-1", "uniprot_id": "FAF_DROME", "id": "P55824-1", "name": "Ubiquitinyl hydrolase FAF", "aln": "MTFDTRRHTTGQPGSTAPSSSSSTTSTTTTTTSPAQSAGSGSGIGTGTGTVANSSLPGGGSGSLDGNQDQQPATDSQSSDDVAASLSANSVDSTITIVPPEKLISSFPTTKLRSLTQKISNPRWVVPVLPEQELEVLLNAAIELTQAGVDHDCEPCVEFYRNGLSTSFAKILTDEAVNSWKNNIHHCILVSCGKLLHLIAIHMQRDNPYLLDLLAIVFDPENKFNTFNAGRQPECFAAPDYIWGQLDSNKMYARPPPEPKNARGWLVDLINRFGQLGGFDNLLERFNIGLELLKRNQNKCTGKNISVEGRVENGAQDNRLTLALIHSLLRPFGQCYELLMPATIAKYFMPTWNVVLDLLDSFTDEELKREVKPEGRNDYINGIVKSARLLASRLTGQEELIRDLEMFRLKMILRLLQVSSFNGKMNALNEINKVLSSVAYFSHRSQPLPHCMPEDEMDWLTADRMAQWIKSSDVLGVVLKDSLHQPQYVEKLEKIIRFLIKEQALTLDDLDAVWRAQAGKHEAIVKNVHDLLAKLAWDFTPEQLDHLFEAFQASMTTANKRQRERLLELIRRLAEDDKNGVMAQKVLKLFWTLAHSQEVPPEVLDQALGAHVKILDYSCSQERDAQKTIWLDKCVDELKSGDGWVLPALRLIRDICCLYDTTTNHAQRTQTST---NRQQVIERLQNDYSLVILVTNSLTAYMEKVRQMVTDSPGLDATRILIDGRFPHHVQIAERLEFLKFLLKDGQLWLCADQAKQIWHCLAVNAVFPADREECFRWFGKLMGEEPDLDPGINKDFFENNILQLDPHLLTESGIKCFERFFKAVNSKEDKLKAIHRGYMLDNEDLIGKDYLWRVITTGGEEIASKAIDLLKEVSTALGPRLQENIAEFHEMFIGECCSRLRTHYGNIVILGKTQLQEELDAPDQSDNTNDESKDSKMRFIEAEKMCRILKVLQEYVKECDRSFSGDRVHLPLSRVTRGKNTILYIRFQNPGRSIDDMEIVTHSNETMAAFKRNLLKRIKGTSTANIKVDLFYANDEMIGVSDEINPLYQYTIRDKMNLTAKLTPVGTGLASSPDSSSDSSTGSPPRPCP----DMQRVESESTLPGVIISQNYQYTEFFLKLYQLGSDLEHGRLRDSAKVLLHLLPCDRQTIRQLKIMCKVPKAAVTVAVTGDKIAKDEEEKLYPTEQAGIEDEEEHCTPEQMFLHPTPAQVLYNLSVLHGLLIPALDPLGESALLVQSAWMHSGCAHFVLELLTKNNFLPSADMHTKRASFQCVLRLAKLFLYIVGSVLSRVGDEPMICDLDNGSRSQVDILKQNFSTMPSSSQGTLRAISAKLAVILAREMLSASPEGDRCRTLFSSTLQWSCPDISTIKAVVQLAWASSCGNLQALGNSSGDFEDEVIVPDGQ-------DFSMCKEALEVLTISFILNPSANEALTSDPNWPKFITSIVLKNPLRHVRQVASEQLFLASTYCAGDRRPFVYMVNLLVGALKTLVPQYESTCAEFFSVLCRTLSYGCIYNWPLQISEGLLGDEIKWLQRIRENVHATGDTQVHEELLEGHLCLAKELMFFLGADSKAQLN------ELIHELIDDFLFTASREFLHLRRHGSLRQDTVPPPVCRSPHTIAAACDLLIALCQLCVPNMKLLTNTLIDFVCTDT-----DPLREWDYLPPVGARPTKGFCGLKNAGATCYMNSVLQQLYMVPAVRVGILRAHGAATTDGEDFSGDSDLTGGGLGSALFSGPASALVSLPSSSSTIEDG-LHDVRKNYHVVILKHVQAIFAHLGHSALQYYVPRGLWTHFKLLGEPVNLREQQDAVEFFMSLLESLDEGLKALGQPQLMNATLGGSFSDQKICQECPHRYSKEEPFSVFSVDIRNHSSLTESLEQYVKGELLEGADAYHCDKCDKKVVTVKRVCVKKLPPVLAIQLKRFEYDYERVCAIKFNDYFEFPRILDMEPYTVSGLAKLEGEVVEVGDN---CQTNVET-------TKYELTGIVVHSGQASGGHYFSYILSKNPA---NGKCQWYKFDDGEVTECKMHEDEEMKAECFGGEYMGETYDNNLKRMQYRRQKRWWNAYMLFYTRCDQTPVQYEPSVEQLSLAES-RNMVLPLPKPIERSVRHQNIRFLHSRSIFSVEFFNFIKKLVSCNLLSARS----NKITPAAEELSLLGVQLASQFLFHTGFRTKKSLRGPVMEWYDALSHHIRSSALVRKWFANHALLSPPSRLGEYILMAPSPDVRTVFVKLVVFFCHFAINDEPLTG---------------YDGANLCEQVLISVLRLLKSEAADYGKHLPHYFSLFSMYVGLGTREKQQLLRLNVPLQFIQVALDDGPGPAIKYQYPEFSKLHQVVSHLIRCSDVSEKCQSSNQNARPLSNPFKDPNVAHEELTPLSTECMDLLFNRTGYIKKVIEDTNVGDEGLKLLQYCSWENPHFSRAVLTELLWQCGFAYCHDMRHHTDLLLNILLIDDSWQHHRIHNALNGVAEEREGLLETIQRAKTHYQKRAYQIIKCLTQLFHKSPIALQMLHTNSNITRHWSIAVEWLQGELDRQRGIG-CQYNSYSWSPPAQSNDNTNGYMLERSQSAKNTWSMAFELCPDEVSEKTDENNEPNLETNMDENKSEPVAQPGGVLEGSTGGTEQLPENKTPTTSSPSTAAWPARGDSNAIPRLSRQLFGAYTSTGSGSTSGGSAPTSALTTTAGSGANSETESSAQETTGETTINGLTNSLDQMEITAKKKCRRVIIKKLVESKDEEDATTATTAATTEVTTSPATAIATAATLEPAGMSELTTMVEKNLIISQENPQAKSSLQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : ....* ... * . .: : . . .: . .:. . : . . :. .:** :.* .* : *...********: ******:*:*:* *:* ..*.* .*:*: *: **:*** ****..** :**:**: . :*:.* . ::.:* :*:***:. :*. **: :*. * * ..: *: .::::* .. : :..:******** ** *.**: * :** * . *.: * :*::***** * * *: ***:* ::* .:*:.:*:****:*.* * :** :. *:* : ****:.**:* :::** ***********:************:***:***:*::* * .*:* ***.:**::**:..::*.:**:***********:***:**:***:****:**: :* **********************:*:* ******:.*: * *.*.*:***:*************:****:***:*:*.**:*::** :::* **.**:*********:**:** *:* ::*:::.: **:***: *::**.*:. :.:: .:*: *. *:::*.:**::::** **::.*::**:.:* : . *. : ..*:.* :: ***:**:***********. ******:*** ***: .*** ** *:.****:****.*.***:***.*:***** ****.*:********:**.:* ** :: **:*: :*** ****:*: ..::*:.:*******: * ***:*: * . :** ** .* .*::: *..: ::. .::.. ** :: *:*.*::**:.* * .: :* **:**. ***: : :** * .:.:::::* :*:* *:.:.:* :::*:: .. :: *::** . .*:: *: : : * .::** :***: :. .:.**********:..* . * . * *. *****:* : :* .*: :: :**. * ***.*::*::*:* * ::.:*: :* :: : : . .. *: .:.::*** .*:: **:** * : : .* :::.* :**.:* :*****.:*:.*:* :: .*::***:* :* .:* . *: . ::* . *.:*: *. : : *: ... . ***..*:*: :: *::.** : : .. :: . . * .:* *****:*:.* * *:* ::*..: * .*: .::* : :**:*.**:** .* *. .:**:::::.**. * . : . . :*.:* : *.*. * : : ** .**.**:*:*: :: **:. *.: :****: ::***: * .:.* :. .*::**:* *:*.**. :*: : *.: . . * ** :* *: *. :**:**. ** *:* :.: * :: . .: **:******.**.*** **************:*****:*.:* .** .. . :* .. . .* . :. . . : **:*:: :*:::* *.**. * ******:*:* :*:* *********:**:*** **::****.:**** * ::. .*****:****** *****. **.*:.:.******..* :*:***:**:*****:****:**:*** ****: :**** **:******:**:** ************* *** ****:* ::** . *. : : : : ::*.*.*::******.****:***:.:* . :*:*****:******.:***** :*********.:*: :***.***********:*** : * : * .*: : : :. .***** :**::*:*.: :*:*:*:*::**::** : . : : * **:::::.:***::*** ***:*** :***. :*****. :* * ** **.::.*: ..*:.**:* .**.::* .* **:**:.**:::* . . *. .*.:::: :.* **: *.:::*:** :**.** **..** ** ***:*.** *: *:**:****.:****.*:.**: ***:*:**..*:. *** :. **.**: * * : : *:. *:** ** *:**:*** . .:: :*** :*.****:** :**:***** ..:: :::: : ***::*::::**** *****.*:*:..:::**::***: *.*:****** ** :. ** ...:* *:*: *.::..:*: *:*** .**:*: * :*. .**** ***:.:***:**:*:**: . : * :* *:* .:. : :* . .:: . * * .. .. : : *. . . * :* . ", "identical_positions": 1054, "similar_positions": 833, "identity": "37.14%" }, { "cls_id": "homologset.agr.MGI:1313275", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A4E8-1", "uniprot_id": "D4A4E8_RAT", "id": "D4A4E8-1", "name": "Endonuclease III-like protein 1", "aln": "-------------------------------------------------MNSG-LRIVTRSRSRATRIA------SEGCREELAP---RETAAEGRKSHKPVRRPRK-----------KQKVH-VAYEVANGEEGEDAEPLKVP-------------------VWEPQ-NWQQQLANIRIMRSKKDAPVDQLG--------AEQC--YDITAPPKVRRYQVLLSLMLSSQTKDQVTAGAMQRLR---------ARGLTVESILQTDDDLLGRLIYPVGFWRSKVKFIKQTTAILQQRYEGDIPASVAELVALPGVGPKMAHLAMAVAWGTVSGIAVDTHVHRIANRLKWTK-KMTKSPEETRRNLEEWLP----SEINGLLVGFGQQICLPVHP--------------RCQACLNKALCPAAQGL--------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35980-1", "uniprot_id": "NTH_MOUSE", "id": "O35980-1", "name": "Endonuclease III-like protein 1", "aln": "-------------------------------------------------MNSG-VRMVTRSRSRATRIA------SEGCREELAP---REAAAEGRKSHRPVRHPRR-----------TQKTH-VAYEAANGEEGEDAEPLKVP-------------------VWEPQ-NWQQQLANIRIMRSKKDAPVDQLG--------AEHC--YDASASPKVRRYQVLLSLMLSSQTKDQVTAGAMQRLR---------ARGLTVESILQTDDDTLGRLIYPVGFWRNKVKYIKQTTAILQQRYEGDIPASVAELVALPGVGPKMAHLAMAVAWGTISGIAVDTHVHRIANRLRWTK-KMTKTPEETRKNLEEWLPRVLWSEVNGLLVGFGQQICLPVHP--------------RCQACLNKALCPAAQDL--------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P78549-2", "uniprot_id": "NTH_HUMAN", "id": "P78549-2", "name": "Endonuclease III-like protein 1", "aln": "-------------------------------------------------MTALSARMLTRSRSLGPGAG------PRGCREEPGPLRRREAAAEARKSHSPVKRPRK-----------AQRLR-VAYEGSDSEKGEGAEPLKVP-------------------VWEPQ-DWQQQLVNIRAMRNKKDAPVDHLG--------TEHC--YDSSAPPKVRRYQVLLSLMLSSQTKDQVTAGAMQRLR---------ARGLTVDSILQTDDATLGKLIYPVGFWRSKVKYIKQTSAILQQHYGGDIPASVAELVALPGVGPKMAHLAMAVAWGTVSGIAVDTHVHRIANRLRWTK-KATKSPEETRAALEEWLPRELWHEINGLLVGFGQQTCLPVHP--------------RCHACLNQALCPAAQGL--------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QBP9-1", "uniprot_id": "F1QBP9_DANRE", "id": "F1QBP9-1", "name": "Endonuclease III-like protein 1", "aln": "-------------------MYMFSRLTVRMNSPY----------FTSAALDSSATETMGKSTINKDGIRRLRSRMAQGLRSEDDPPKVKAEVQEKSISDDPTHAHNP-----------ADCVKSTSYNTTSKMKEEPDQALLSPRKRGRGHLKVEYETEGVGLKREPY-DWRTQLSFIREMRSKRDAPVDQMG--------AEKC--YDTQGLPEVRRYQVLISLMLSSQTKDQVTAGAMQRLR---------EHGLSVDGILKMDDETLGKLIYPVGFWRTKVKYIKQATALIQQEFGGDIPNTVEGLIRLPGVGPKMAHLAMDIAWNQVSGIGVDTHVHRISNRLGWTK-KETKTPEETRRALEEWLPRDLWSEINWLLVGFGQQVCLPVGP--------------LCSVCLNQHTCPSAHRSSPSKKIKSSPAKPNNKLASPTALVKEEPEDTSAQRVSHQRRKNTGPQLNQQDLSASRQETPSLARNRRKGRAGAPLSGQT", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VIH0-1", "uniprot_id": "Q9VIH0_DROME", "id": "Q9VIH0-1", "name": "Endonuclease III homolog", "aln": "MAKNVKKLTLANKLAKRGDLIKPTEIKSRPNRADNVRDIEDLVGVSAGAAGSSSSVFFSPVQTRKQRLLNGEAVKKTNIKMEPLSP-ARVAPKKFRKDDRMVTRVQMGSATVVICKVVPDAVDSPVRVDKIREEVEPQIKQEAPE-----------DSPSFSEVQAPHPLWFNHLENIRIMRNSRTAPVDTMG--------CHRC--ADLKADSKTQRFQNLVALMLSSQTKDQTTYEAMNRLK---------DRGLTPLKVKEMPVTELENLLHPVSFYKNKAKYLKQTVEILTDKYGSDIPDNVKDLVALPGVGPKMAHICMAVAWNKITGIGVDVHVHRLSNRLGWVP-KPTKEPEQTRVALEKWLPFSLWSEVNHLFVGFGQTICTPVKP--------------NCGECLNKDICPSAHAETKEKRKKDR-----------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08214-1", "uniprot_id": "NTH2_YEAST", "id": "Q08214-1", "name": "Endonuclease III homolog 2", "aln": "---------------------------------------------MREESRSRKRKHIPVDIEEVEVRSKYFKKNERTVELVKENKINKDLQNYGGVNIDWIKALKP--------IEYFEWIESRTCDDPRTWGRPITKEEMIND-----------------SGAKVPESFLPIYNRVRLMRSKVKTPVDAMGCSMIPVLVSNKCGIPSEKVDPKNFRLQFLIGTMLSAQTRDERMAQAALNITEYCLNTLKIAEGITLDGLLKIDEPVLANLIRCVSFYTRKANFIKRTAQLLVDNFDSDIPYDIEGILSLPGVGPKMGYLTLQKGWGLIAGICVDVHVHRLCKMWNWVDPIKCKTAEHTRKELQVWLPHSLWYEINTVLVGFGQLICMARGK--------------RCDLCLANDVCNARNEKLIESSKFHQ-LEDKE----DIEKVYSHWLDTVTNGITTERHKKK------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P31378-1", "uniprot_id": "NTH1_YEAST", "id": "P31378-1", "name": "Endonuclease III homolog 1", "aln": "---------------------------------------------MQKIS-----KYSSMAILRKRPLVKTETGPESELLPEKRTKIKQEEVVPQPVDIDWVKSLPN--------KQYFEWIVVRNGNVPNRWATPLDPSILVTP-----------------ASTKVPYKFQETYARMRVLRSKILAPVDIIGGSSIPVTVASKCGISKEQISPRDYRLQVLLGVMLSSQTKDEVTAMAMLNIMRYCIDELHSEEGMTLEAVLQINETKLDELIHSVGFHTRKAKYILSTCKILQDQFSSDVPATINELLGLPGVGPKMAYLTLQKAWGKIEGICVDVHVDRLTKLWKWVDAQKCKTPDQTRTQLQNWLPKGLWTEINGLLVGFGQIITKSRNLGDMLQFLPPDDPRSSLDWDLQSQLYKEIQQNIMSYPKWVKYLEGKRELNVEAEINVKHEEKTVEETMVKLENDISVKVED-------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : : :* :*.. :*** :* :* . .. * * *:. ***:**:*: * .: .*:: : : * .*: *.* *.::: : :: :.: .*:* : :: ********.:: : .*. : ** **.**.*: : *. * .:.** *: *** *:* ::***** . * . : ", "identical_positions": 57, "similar_positions": 66, "identity": "11.29%" }, { "cls_id": "homologset.agr.MGI:1313276", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62442-1", "uniprot_id": "VAMP1_MOUSE", "id": "Q62442-1", "name": "Vesicle-associated membrane protein 1", "aln": "MSAPAQPPAEGTEGAAPGGGPPGPPP--------------NMTSNRRLQQTQAQVEEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFESSAAKLKRKYWWKNCKMMIMLGAICAIIVVVIVIYFFT--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P23763-1", "uniprot_id": "VAMP1_HUMAN", "id": "P23763-1", "name": "Vesicle-associated membrane protein 1", "aln": "MSAPAQPPAEGTEGTAPGGGPPGPPP--------------NMTSNRRLQQTQAQVEEVVDIIRVNVDKVLERDQKLSELDDRADALQAGASQFESSAAKLKRKYWWKNCKMMIMLGAICAIIVVVIVIYFFT--------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q63666-1", "uniprot_id": "VAMP1_RAT", "id": "Q63666-1", "name": "Vesicle-associated membrane protein 1", "aln": "MSAPAQPPAEGTEGAAPGGGPPGPPP--------------NTTSNRRLQQTQAQVEEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASVFESSAAKLKRKYWWKNCKMMIMLGAICAIIVVVIVIYIFT--------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P18489-1", "uniprot_id": "SYB_DROME", "id": "P18489-1", "name": "Synaptobrevin", "aln": "MENNEAPSPSGSNNNDFPILPPPPNANDNYNQFGDHQIRNNNAAQKKLQQTQAKVDEVVGIMRVNVEKVLERDQKLSELGERADQLEQGASQFEQQAGKLKRKQWWANMKMMIILGVIAVVLLIIVLVSVWPSSSDSGSGGGNKAITQAPPH", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P31109-1", "uniprot_id": "SNC1_YEAST", "id": "P31109-1", "name": "Synaptobrevin homolog 1", "aln": "MSSSTPFDPYALSEHD----EERPQ---------------NVQSKSRTAELQAEIDDTVGIMRDNINKVAERGERLTSIEDKADNLAVSAQGFKRGANRVRKAMWYKDLKMKMCLALVIIILLVVIIVPIAVHFSR----------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. . . . * * :: : : **::::.*.*:* *::** **.::*:.: ::** * .*. *: * :::: *: : ** : *. : :::::::: . ", "identical_positions": 24, "similar_positions": 46, "identity": "15.79%" }, { "cls_id": "homologset.agr.MGI:1313277", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P63044-1", "uniprot_id": "VAMP2_MOUSE", "id": "P63044-1", "name": "Vesicle-associated membrane protein 2", "aln": "MSATAATVPPAAPAGEGGPPAPPPNLTSN----------------RRLQQTQAQVDEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFETSAAKLKRKYWWKNLKMMIILGVICAIILIIIIVYFST--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P63045-1", "uniprot_id": "VAMP2_RAT", "id": "P63045-1", "name": "Vesicle-associated membrane protein 2", "aln": "MSATAATVPPAAPAGEGGPPAPPPNLTSN----------------RRLQQTQAQVDEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFETSAAKLKRKYWWKNLKMMIILGVICAIILIIIIVYFST--------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P63027-1", "uniprot_id": "VAMP2_HUMAN", "id": "P63027-1", "name": "Vesicle-associated membrane protein 2", "aln": "MSATAATAPPAAPAGEGGPPAPPPNLTSN----------------RRLQQTQAQVDEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFETSAAKLKRKYWWKNLKMMIILGVICAIILIIIIVYFST--------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P18489-1", "uniprot_id": "SYB_DROME", "id": "P18489-1", "name": "Synaptobrevin", "aln": "MENNEAPSPSGSNNNDFPILPPPPNANDNYNQFGDHQIRNNNAAQKKLQQTQAKVDEVVGIMRVNVEKVLERDQKLSELGERADQLEQGASQFEQQAGKLKRKQWWANMKMMIILGVIAVVLLIIVLVSVWPSSSDSGSGGGNKAITQAPPH", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P31109-1", "uniprot_id": "SNC1_YEAST", "id": "P31109-1", "name": "Synaptobrevin homolog 1", "aln": "MSSSTPFDPYALSEHD---EERPQNVQSK----------------SRTAELQAEIDDTVGIMRDNINKVAERGERLTSIEDKADNLAVSAQGFKRGANRVRKAMWYKDLKMKMCLALVIIILLVVIIVPIAVHFSR----------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. . . * . : * * .: : : **::*:.*.*** *::** **.::*:.: ::** * .*. *: * :::: *: ::** : *.:: ::*::::* . ", "identical_positions": 29, "similar_positions": 45, "identity": "19.08%" }, { "cls_id": "homologset.agr.MGI:1313278", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K4C8-1", "uniprot_id": "FZD9_RAT", "id": "Q8K4C8-1", "name": "Frizzled-9", "aln": "MAVPPLLRGALLLWQLLATGGAALEIGRFDPERGRGPAPCQAMEIPMCRGIGYNLTRMPNLLGHTSQGEAAAQLAEFSPLVQYGCHSHLRFFLCSLYAPMCTDQVSTPIPACRPMCEQARLRCAPIMEQFNFGWPDSLDCARLPTRNDPHALCMEAPENATAGPTEPHKGLGMLPVAPRPARPPGDSAPGPGSGGTCDNPEKFQYVEKSRSCAPRCGPGVEVFWSRRDKDFALVWMAVWSALCFFSTAFTVFTFLLEPHRFQYPERPIIFLSMCYNVYSLAFLIRAVAGAQSVACDQEAGALYVIQEGLENTGCTLVFLLLYYFGMASSLWWVVLTLTWFLAAGKKWGHEAIEAHGSYFHMAAWGLPALKTIVVLTLRKVAGDELTGLCYVASMDPAALTGFVLVPLSCYLVLGTSFLLTGFVALFHIRKIMKTGGTNTEKLEKLMVKIGVFSILYTVPATCVIVCYVYERLNMDFWRLRATEQPCTAAAVPGGRRD-CSLPGGSVPTVAVFMLKIFMSLVVGITSGVWVWSSKTFQTWQSLCYRKMAAGRARAKACRTPGGYGRGTHCHYKAPTVVLHMTKTDPSLENPTHL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R216-1", "uniprot_id": "FZD9_MOUSE", "id": "Q9R216-1", "name": "Frizzled-9", "aln": "MAVPPLLRGALLLWQLLATGGAALEIGRFDPERGRGPAPCQAMEIPMCRGIGYNLTRMPNLLGHTSQGEAAAQLAEFSPLVQYGCHSHLRFFLCSLYAPMCTDQVSTPIPACRPMCEQARLRCAPIMEQFNFGWPDSLDCARLPTRNDPHALCMEAPENATAGPTEPHKGLGMLPVAPRPARPPGDSAPGPGSGGTCDNPEKFQYVEKSRSCAPRCGPGVEVFWSRRDKDFALVWMAVWSALCFFSTAFTVFTFLLEPHRFQYPERPIIFLSMCYNVYSLAFLIRAVAGAQSVACDQEAGALYVIQEGLENTGCTLVFLLLYYFGMASSLWWVVLTLTWFLAAGKKWGHEAIEAHGSYFHMAAWGLPALKTIVVLTLRKVAGDELTGLCYVASMDPAALTGFVLVPLSCYLVLGTSFLLTGFVALFHIRKIMKTGGTNTEKLEKLMVKIGVFSILYTVPATCVIVCYVYERLNMDFWRLRATEQPCTAATVPGGRRD-CSLPGGSVPTVAVFMLKIFMSLVVGITSGVWVWSSKTFQTWQSLCYRKMAAGRARAKACRTPGGYGRGTHCHYKAPTVVLHMTKTDPSLENPTHL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00144-1", "uniprot_id": "FZD9_HUMAN", "id": "O00144-1", "name": "Frizzled-9", "aln": "MAVAP-LRGALLLWQLLAAGGAALEIGRFDPERGRGAAPCQAVEIPMCRGIGYNLTRMPNLLGHTSQGEAAAELAEFAPLVQYGCHSHLRFFLCSLYAPMCTDQVSTPIPACRPMCEQARLRCAPIMEQFNFGWPDSLDCARLPTRNDPHALCMEAPENATAGPAEPHKGLGMLPVAPRPARPPGDLGPGAGGSGTCENPEKFQYVEKSRSCAPRCGPGVEVFWSRRDKDFALVWMAVWSALCFFSTAFTVLTFLLEPHRFQYPERPIIFLSMCYNVYSLAFLIRAVAGAQSVACDQEAGALYVIQEGLENTGCTLVFLLLYYFGMASSLWWVVLTLTWFLAAGKKWGHEAIEAHGSYFHMAAWGLPALKTIVILTLRKVAGDELTGLCYVASTDAAALTGFVLVPLSGYLVLGSSFLLTGFVALFHIRKIMKTGGTNTEKLEKLMVKIGVFSILYTVPATCVIVCYVYERLNMDFWRLRATEQPCAAAAGPGGRRD-CSLPGGSVPTVAVFMLKIFMSLVVGITSGVWVWSSKTFQTWQSLCYRKIAAGRARAKACRAPGSYGRGTHCHYKAPTVVLHMTKTDPSLENPTHL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A3QK10-1", "uniprot_id": "A3QK10_DANRE", "id": "A3QK10-1", "name": "", "aln": "--MGHCMKIGIGLFQIMIAA-STLEIGAYDLEHGR-PGKCEPITIPMCQGIGYNMTRMPNLLNYESQEEASIKLNEFAPLVKYGCDIHLQFFLCSLYVPMCAEQVSASIPACRPMCEQARQRCSPIMEQFSFSWPDSLDCSKLPTNNDPNALCIEAPENDTQ--PETKKGEGMLPVPPRSRQPTTVSGRISSISQSCENPEKFQYVDKSESCAPRCTPTVDVYWSRQDKDFAFIWMVVWSTLCFVSTAFTVLTFLLDPQRFQYPERPIIFLSMCYNIYSVAFIIRSVAGAENIACDRENGELYIIREGLESTGCTIVFLILYYFGMASSIWWVILTLTWFLAAGRKWGHEAIEAHSSYFHMAAWGIPAVKTIVILTMRKVAGDELTGLCYVGSMDSSALTGFVLIPLSCYLIVGTSFILTGFVALFHIRKIMKTGGTNTEKLEKLMVKIGVFSILYTVPATIVIICYFYERLNMEYWKFRALENKCVS--FPGRRSDDCSLDS-SVPTVAVFMLKIFMSLVVGITSGVWVWSSKTLQTWQGLYNRRLGVQTS-HKPCSSVSCSN--SHCHYKAPAVTIHMNKTDAYTDSPTHV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: .: *:*:: :. ::**** :* *:** .. *:.: ****:*****:*******.: ** **: :* **:***:***. **:*******.***::***:.************ **:******.*.*******::***.***:***:***** * .*.:** *****.**. :*. . .. . :*:********:**.****** * *:*:***:*****::**.***:***.******:****:*:*****************:**:**:**:****:.:***:* * **:*:****.****:***:*********:***:**********:**********.*********:**:****:**:**************.* *.:*******:*** **::*:**:******************************************* **:**.******::*::** *: *.: ** * * *** . *******************************:****.* *::.. : *.* : . . :*******:*.:**.***. :.***:", "identical_positions": 402, "similar_positions": 127, "identity": "67.79%" }, { "cls_id": "homologset.agr.MGI:1313286", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P70541-1", "uniprot_id": "EI2BG_RAT", "id": "P70541-1", "name": "Translation initiation factor eIF2B subunit gamma", "aln": "-MEFQAVVMAVGG-------------------------GSRMTDLTS----------------SIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTKDVQKALCAEFK-------------------------MKLKPDIVCIPDEADMGTADSLRHIYPKLKTDVLVLGCDLITDVALHEVVDLFR-AYDASLAMLMR-KGQESTEPVPGQKGKKKTVEQRDFIGVDSTGKR-----LLFMANEADLDEELVIKGSILQKHPRIHFQTGLVDAHLYCLKKYVVDFLMENKSITSIRSELIPYLVRKQFSSASSQQRQEDKEED--LKKKEPKSLDIYSFIKKDNTLTLAPYDACWNAFRRDKWEDLSRSQVRCY--------VHIMKEGLCSRVSTLGLYMEANRQVPKLLSVLCPEESMIHPSAQIANKHLIGADSLIGSDTQVGEKSSIKRSVIGSSCVIRDRVTVTNCLLMNSVTVEEGSSIHGSVICNNAVVEAGAEIRDCLIGSGQRIEAK----AKRMNEVIVGNDQLMEI----------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B1AUN2-1", "uniprot_id": "B1AUN2_MOUSE", "id": "B1AUN2-1", "name": "Translation initiation factor eIF2B subunit gamma", "aln": "-MEFQAVVMAVGG-------------------------GSRMTDLTS----------------SIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTKDVQKALCAEFK-------------------------MKMKLDIVCIPDEADMGTADSLRHIYPKLKTDVLVLSCDLITDVALHEVVDLFR-AYDASLAMLMR-KGQESIEPVPGQKGKKKPVEQRDFIGVDSTGKR-----LLFMANEADLDEELVIKGSILQKHPRIHFHTGLVDAHLYCLKKYVVDFLMENRSITSIRSELIPYLVRKQFSSASSQQRQEDKEED--LKKKELKSLDIYSFIKKDDTLTLAPYDACWNAFRGDKWEDLSRSQVRCY--------VHIMKEGLCSRVSTLGLYMEANRQVPKLLSVLCPEESMIHSSAQIVNKHLIGADSLIGPDTQIGEKSSIKHSVIGSSCVIRDRTSITNCLLMNSVTVEEGSSIHGSVICNNAVIETGAEIKNCLVGSGQRIEAK----AKRMNEVIVGNDQLMEI----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NR50-1", "uniprot_id": "EI2BG_HUMAN", "id": "Q9NR50-1", "name": "Translation initiation factor eIF2B subunit gamma", "aln": "-MEFQAVVMAVGG-------------------------GSRMTDLTS----------------SIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRDVQKALCAEFK-------------------------MKMKPDIVCIPDDADMGTADSLRYIYPKLKTDVLVLSCDLITDVALHEVVDLFR-AYDASLAMLMR-KGQDSIEPVPGQKGKKKAVEQRDFIGVDSTGKR-----LLFMANEADLDEELVIKGSILQKHPRIRFHTGLVDAHLYCLKKYIVDFLMENGSITSIRSELIPYLVRKQFSSASSQQGQEEKEED--LKKKELKSLDIYSFIKEANTLNLAPYDACWNACRGDRWEDLSRSQVRCY--------VHIMKEGLCSRVSTLGLYMEANRQVPKLLSALCPEEPPVHSSAQIVSKHLVGVDSLIGPETQIGEKSSIKRSVIGSSCLIKDRVTITNCLLMNSVTVEEGSNIQGSVICNNAVIEKGADIKDCLIGSGQRIEAK----AKRVNEVIVGNDQLMEI----------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1ZA22-1", "uniprot_id": "A1ZA22_DROME", "id": "A1ZA22-1", "name": "Translation initiation factor eIF2B subunit gamma", "aln": "MTEFQAVVFAAGR-------------------------GTRLPEVLG----------------DAPKCLLPVGPYPLIWYPLNLLQQHNFTEVIVVVLEQEKLEIQSALENTP----------------------LKLRLDYATIPSDGDFGTADSLRYIYDKIKSDFLVVSCDLVSNVSLYPLINKFR-EHDAALAMLLFPSGFESDVVMPGPKSKHK--PERDLIGIHAATQR-----LAFVSAASDCEETLNIQRHLLKNRGRLDVYSRLVDAHVYVLKKWVIDYLRRKENISTFKGEFLPHLIKKQHSKRPPKTVQDTTSEVGVVTKNEDHVLHYVGHTILDQKITQT---SLFNQSLSQ--SPYHGDIVRCYG-------IQAPRDAIGVRVNNTLSFLAINRKLASIWNNLCGEKHPLISPGAVVKSTQT-KEIIAADNAKLSEKTSLNFSVFGPNCIISPKNIVANSLIMSNAIVEEGCNIDNCIIGHRAQVKSGSVLKNCIIGPNYVVEEG----THSQAVHLSNADQFMEIDIQ-------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P09032-1", "uniprot_id": "EI2BG_YEAST", "id": "P09032-1", "name": "Translation initiation factor eIF2B subunit gamma", "aln": "-MSIQAFVFCGKGSNLAPFTQPDFPFQTQNKDSTAATSGDKLNELVNSALDSTVINEFMQHSTRLPKALLPIGNRPMIEYVLDWCDQADFKEISVVAPVDEIELIESGLTSFLSLRKQQFELIYKALSNSNHSHHLQDPKKINFIPSKANSTGESLQKELLPRINGDFVILPCDFVTDIPPQVLVDQFRNRDDNNLAMTIYYKNSLDSSIDKKQQQKQKQQQFFTVYSENEDSERQPILLDVYSQRDVTKTKYLQIRSHLLWNYPNLTVSTKLLNSFIYFCSFELCQLLKLGPQSMSRQASFKDPFTGNQQQQNPPTTDDDEDRNHD-DDDDYKPSATSIQPTYFKKKNDLILDPINCNKSLSKVFRDLSRRSWQHSKPREPIGIFILPNETLFIRANNLNAYMDANRFVLKIKSQTMFTKNIQIQSAAIG------ADAIVDPKCQISAHSNVKMSVLGTQANIGSRCRVAGSLLFPGVHLGDEVILENCIIGPMAKIGSKCKLSNCYIEGHYVVEPKNNFKGETLANVYLDEDEEDELIYDDSVIAGESEIAEETDSDDRSDEDSDDSEYTDEYEYEDDGLFER", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:**.*:. * :: :: . ** ***:* *:* * *: :: .* *: **. : : : : :: . **...: . : : ::: *.::: **:::::. ::: ** * *** : .. . : *:* . . . :* : : * *: :* : .: . : *:::.:* . : : * . : :..: : :* .. .. :: : .. .. * . : . .: : *... :: ** : .: . : .. : : : . ::. ::.:: **:*... * : ::..*:: .. : : :...:* * : . : :* : :* . . *: *: ", "identical_positions": 54, "similar_positions": 154, "identity": "9.22%" }, { "cls_id": "homologset.agr.MGI:1313288", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WU62-1", "uniprot_id": "INCE_MOUSE", "id": "Q9WU62-1", "name": "Inner centromere protein", "aln": "------------------------MGTTAPGPICLLDLCDQKLLDFVCNVDNKDFMWLKEIEEEAERMFIREFSNEPELMPKTPSQKNRRKKRRVSNIQDENRDPVRKRLSRRKSRSSQVGTRHLRSK-----PVTIVEENGFPVLQRITRATAAAAAAAA--AASVASASSSSTAGSPTVLTKK-----------AVVEISTSERLSAELQLTKLKGSLP------------PSPVSQGTLTSEEELTPKKSEAGKLD----SVTVNSLKATPQSPKNRGVGEGRSVSKLKIARASWGLQDSPGSTDSPWQERVLSPILLNNILPTTAKSPLGNIRSVRRSLISQDSQVP--LASKYNLVAKQENGSRRSSRRIAKKAGKEPEASARIICHSYLERLLNVEVPQNVGLE-QEPVEVAEPEEAEEEQEVSKNSGCPSKPRSATKIAISTPTSKPAAAG-QTTTVEEQEAELDQTDGHREPPQSVRRKRSYKQAISEPDEE-QLEDEELQPCQNKTPSPPCPANKVVRPLRTFLHTVQKNQMLMTPTLASRSSVMKSFIKRNTPLRVDPKCSFVEKERQRLESLRRKEEAEQRRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEK-AKKKATAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQEMLQRKKEEEQER-RKAAEARRLAEQREQERRREQERREQERREQERREQERKEQERREQE--------QERLRAKREMQEREKALRLQKERLQKELEEKKRKEEQQRLAEQQLQEEQAKKAKEVAAARKVLNMTVDVQSPVCTSYQMTPQGPKSIPKISVDDYGMDLNSDDSTDDESHPRKPIPSWAKGTQLSQAIVHQYYHPPNILELFGSILPLDLEDIFKKRKTRYHKRTSSAVWNSPPLKATMVPSSGD------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZZ56-1", "uniprot_id": "A0A8I5ZZ56_RAT", "id": "A0A8I5ZZ56-1", "name": "Inner centromere protein", "aln": "MEGEVGTGSRGRRHCNQDILYSATMGTTAPGPANLLDLCDQKLLDFVYNVDNKDFMWLKEIEEEAERMFVREFNNEPELMPKTPSQKNRRKKRRVSNIQDENRDPVRKRLSRRKSRSSQVGPRHRRSK-----LGAVVEENGSPVLRRITRAAAAAAAAAASTSASVASASSSPTTVSPIVLIKK-----------AVVEVSTGEQLSAELQLIKLKGGLPQ----SSVPAPATSSVSQGTLTSEEEATPKKSEAGRLDSATDSVAVNSLKATPQSPKNRGVGEARSVSKLKIARASRGLQDSPGSTDSPWQERVLSPILPNNILSTTAKNPLGSIQSVQQSLISQDSQVP--LAKKYCLVTQQENASRRSSR-IAKKAGKEPEASARIICHSYLERLLNVEVPQNVGLE-KEPVEVAEPEEAVEEQEVSKNSGCSSKPHSATKMAISTPTSKPVATG-QATAVEEQDAELDQTDGHREPPQSVRRKRSYKQAMSELDEE-HLEDEELQPPRNKTPSPPCPASKVVRPLRTFLHTVQKNQMLMTPTLASRSSVMKSFIKRNTPLRVDPKCSFVEKERQRLESLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEK-AKKKAAAKKMEEMEARRKQEEEARRLKWLQQEEEERRHQEMLQRKKEEEQER-RKAAEARRLAEQREQERRREQERREQERREQERREQERREQERREQERREQERREQERLRAKREMQEREKALRLQKERLQRELEEKKKKEEQQRLAEQQLQEEQAKKAKEVAAG-KALNMTVDVQSPVCTSYQMTPQGPKSFPKISMDDYGMDLNSDDSTDDEAHPRKPIPSWAKGTQLSQAIVHQYYHPPNILELFGSILPLDLEDIFKKRKTRYHKRTSSAVWNSPPLKAT-IPSSGD------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NQS7-1", "uniprot_id": "INCE_HUMAN", "id": "Q9NQS7-1", "name": "Inner centromere protein", "aln": "------------------------MGTTAPGPIHLLELCDQKLMEFLCNMDNKDLVWLEEIQEEAERMFTREFSKEPELMPKTPSQKNRRKKRRISYVQDENRDPIRRRLSRRKSRSSQLSSRRLRSKDSVEKLATVVGENGS-VLRRVTRAAAAAAAATM-----ALAAPSSPTPESPTMLTKKPEDNHTQCQLVPVVEIGISERQNAEQHVTQLMSTEPLPRTLSPTPASATAPTSQGIPTSDEESTPKKSKARILE----SITVSSLMATPQDPKGQGVGTGRSASKLRIAQVSPGPRDSPAFPDSPWRERVLAPILPDNFSTPTGSR--TDSQSVRHSPIAPSSPSPQVLAQKYSLVAKQESVVRRASRRLAKKTAEEPAASGRIICHSYLERLLNVEVPQKVGSEQKEPPEEAEP-VAAAEPEVPENNGNNSWPHNDTEIANSTPNPKPAASSPETPSAGQQEAKTDQADGPREPPQSARRKRSYKQAVSELDEEQHLEDEELQPPRSKTPSSPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPR-SVMKSFIKRNTPLRMDPKCSFVEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERR-EQERREQERREQERREQERREQERQLAE--QERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASKALNVTVDVQSPACTSYQMTPQGHRAPPKINPDNYGMDLNSDDSTDDEAHPRKPIPTWARGTPLSQAIIHQYYHPPNLLELFGTILPLDLEDIFKKSKPRYHKRTSSAVWNSPPLQGARVPSSLAYSLKKH", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ******** **:******::*: *:****::**:**:******* ***.:*******************:* :*******:*:***********:..*: *** ::* *** **:*:***:******: . :*.**.*. ** :* ** .***:. .*: .** :: :* . * .:..*** **:** *****:* *: *::*.** ****.**.:*** .**.***:**:.* * :***. .****:****:*** :*: ..*.. . :**::* *: .* * **.** **::**. **:** :***:.:** **.******************:** * :** * *** * * **.:*.* * *:. *::* ***..**.*:. ::.:. :*:*: **:** ******.*********:** *** :******** :.****.****.**************:******** *.* **************:***************.********* ******************************************************************: *****:******:*************:*************:**:******** ******:*********** *******************:****: * ****:*:**:************:**:******:*********:****** *****.*.. *.**:*******.********** :: ***. *:**************:*******:**:** *****:********:*****:************ *.****************:.: :*** ", "identical_positions": 637, "similar_positions": 157, "identity": "66.42%" }, { "cls_id": "homologset.agr.MGI:1313291", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5SXC4-1", "uniprot_id": "Q5SXC4_MOUSE", "id": "Q5SXC4-1", "name": "", "aln": "-MEANWTAFLFQ-AHEASHHQQQAAQNSLLPLLSSAVEPPDQKPLLPIPITQKP-QAAPETLKDAIG-----------------IKKE-KPKTSFVCTYCSKAFRDSYHLRRHQSCHTGIKLVSRAKKTP---TTVVPLISTIAGDSSR-TSLVSTIAGILSTVTTS-SSGTNPSSSASTTSMPVPQSVKKPSKPVKKNHACEMCGKAFRDVYHLNRHKLSHSDEKPFECPICNQRFKRKDRMTYHVRSHEGGITKPYTCSVCGKGFSRPDHLSCHVKHVHSTERPFKCQT--CTAAFATKDRLRTHMVRHEGKVSCNICGKLLSAAYITSHLKTHGQSQSINCNTCKQGISKTCMSEETSNQKQQQQQQQQQQQQQQQ---HVTSWPGKQVETLRLWEEAVKARKKEAANLCQTSTAATTPVTLTTPFNITSSVSSGTMSNPVTVAAAMSMRSPVNVSSAVNITSPMNIGHPVTITSPLAMTSPLTLTTPVNLPTPVTAPVNIAHPVTITSPMNLPTPMTLAAPLNIAMRPVESMPFLPQALPTSPPW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZLS0-1", "uniprot_id": "A0A8I5ZLS0_RAT", "id": "A0A8I5ZLS0-1", "name": "", "aln": "-MEANWTAFLFQ-AHEASHHQQQAAQNSLLPLLSSAVEPPDQKPLLPIPITQKP-QAAPETLKDAIG-----------------IKKE-KPKTSFVCTYCSKAFRDSYHLRRHQSCHTGIKLVSRAKKTP---TTVVPLISTIAGDSSR-TSLVSTIAGILSTVTTS-SSGTNPSSSASTTAMPVPQSVKKPSKPVKKNHACEMCGKAFRDVYHLNRHKLSHSDEKPFECPICNQRFKRKDRMTYHVRSHEGGITKPYTCSVCGKGFSRPDHLSCHVKHVHSTERPFKCQT--CTAAFATKDRLRTHMVRHEGKVSCNICGKLLSAAYITSHLKTHGQSQSINCNTCKQGISKTCMSEETSNQKQQQQQQQQQQQQQQQQQ-HVTSWPGKQVETLRLWEEAVKARKKEAANLCQTSTAATTPVTLTTPFNITSSVSSGTMSNPVTVAAAMSMRSPVNVSSAVNITSPMNIGHPVTITSPLSMTSPLTLTTPVNLPTPVTAPVNIAHPVTITSPMNLPTPMTLAAPLNIAMRPVESMPFLPQALPTSPPW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q14119-1", "uniprot_id": "VEZF1_HUMAN", "id": "Q14119-1", "name": "Vascular endothelial zinc finger 1", "aln": "-MEANWTAFLFQ-AHEASHHQQQAAQNSLLPLLSSAVEPPDQKPLLPIPITQKP-QGAPETLKDAIG-----------------IKKE-KPKTSFVCTYCSKAFRDSYHLRRHESCHTGIKLVSRPKKTP---TTVVPLISTIAGDSSR-TSLVSTIAGILSTVTTS-SSGTNPSSSASTTAMPVTQSVKKPSKPVKKNHACEMCGKAFRDVYHLNRHKLSHSDEKPFECPICNQRFKRKDRMTYHVRSHEGGITKPYTCSVCGKGFSRPDHLSCHVKHVHSTERPFKCQT--CTAAFATKDRLRTHMVRHEGKVSCNICGKLLSAAYITSHLKTHGQSQSINCNTCKQGISKTCMSEETSNQKQQQQQQQQQQQQQQQQQQHVTSWPGKQVETLRLWEEAVKARKKEAANLCQTSTAATTPVTLTTPFSITSSVSSGTMSNPVTVAAAMSMRSPVNVSSAVNITSPMNIGHPVTITSPLSMTSPLTLTTPVNLPTPVTAPVNIAHPVTITSPMNLPTPMTLAAPLNIAMRPVESMPFLPQALPTSPPW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F042-1", "uniprot_id": "E7F042_DANRE", "id": "E7F042-1", "name": "Myc-associated zinc finger protein", "aln": "MMEQSWSSFLFQQANEALHHQHQVAPNSLLPLLNS--EPQDQKPVMPIPLDHKPPVSAADLLKDNVVSGTGGGGGGGNAGPMVVVKKEHKSKTPFICGYCNKAFRDSYHLRRHESCHTGIKMVSRPKKTAQAAPTMVPLISSMSRESTGDPSYISTVAGILSTATTSTSSASTVMSPTSMSNVTQHSAPKKPPKPVKKNHGCEMCGKAFRDVYHLNRHKLSHSDEKPFECPICQQRFKRKDRMTYHVRSHDGGVHKPYVCSVCGKGFSRPDHLSCHVKHVHSSERPFKCQVTACTSAFATKDRLRSHMIRHEGKVTCNVCGKMLSAAYITSHLKTHGQSNFN--NACNKGYALSVHGARHSGD----------------------------------WQWNHSGLRKDNTEVCN--SASSTPVTPAAP--ITSTMNRGNTSNPVTIAAQMNIS-----TNTVNITSPVSLQHQVTITGPVNIAS-------VNIP--ASAPMNIAHPVAITTPM----PMNIATPLNIAMRPMDSMPFLSQVLPSSP-W", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** .*::**** *:** ***:*.* *******.* ** ****::***: :** .*.: *** : :*** *.**.*:* **.************:*******:***.***. .*:*****::: :*: .* :**:******.*** **.:. *.:* : :. .: ***.*******.********************************:****************:**: ***.***********************:*******. **:*********:**:******:**:***:****************: *:*::* : : . . *.: *: .. :*: :::*: :*::**** ::* ***::. *. *****:** *.: :.:******:.: * ****.*: ::* **:* .:**:******:**:** **.:*:********::*****.*.**:** *", "identical_positions": 304, "similar_positions": 114, "identity": "55.37%" }, { "cls_id": "homologset.agr.MGI:1313297", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QY42-1", "uniprot_id": "GPR37_MOUSE", "id": "Q9QY42-1", "name": "Prosaposin receptor GPR37", "aln": "MPARGAPLSRTSRLLLLLLFKVSVSAALSFVPEPRNGTCLGESCSP--LIQRRSRDARGPGNSAKDALRVHVPREKLEAEVRGATS--WDLPPPRGGD--TGVIEEAAAAGPLGPPTKPPSAWRWKSAQGKEPSGHLRRRDPTDPQLFFPTSEGGEMSSKRDGIPQSRQEHSVKTEP--RDLFYWPRRTGQLQDSQHRPS-------AVHEGRTLAPPGRALPQNGS--ADDWVPDQGGPRRGNTT-RRVRLKNPFYPLTQESYGAYAVMCLSVVIFGTGIIGNLAVMCIVCHNYYMRSISNSLLANLAFWDFLIIFFCLPLVIFHELTKKWLLEDFSCKIVPYIEVASLGVTTFTLCALCIDRFRAATNVQMYYEMIENCSSTTAKLAVIWVGALLLALPEVVLRQLSKEDLGFSGQAP-AERCVIKISPDLPDTIYVLALTYDGARLWWYFGCYFCLPTLFTITCSLVTARKIRKAEKASTRGNKRQIHLESQMNCTVVALTILYGFCIIPENICNIVTAYMATGVSQQTMDLLNIISQFLLFFKSCVTPVLLFCLCRPFSRAFMECCCCCCEECIQ---KSSTVTSDDNDNEYTTELELSPFSTI-RREMSTFASVGTHC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9QYC6-1", "uniprot_id": "GPR37_RAT", "id": "Q9QYC6-1", "name": "Prosaposin receptor GPR37", "aln": "MPAPGAPLSRTSRLLLLLLFKVSVSAALSFVPEPRNGTCLGESCSP--LIPRRSRDAGGPRNSARDALRVHVPREKLEAEVRGATS--WDLPPPRGGD--TGVIEEAAASGPLGPPTKPPGAWRWKGAQGKEPSGHLGRREPTDSQLFRQTSERGEMSSKRDEIPQGSQEHSVKTEPEPRDLFYWPRKTGQLQGSHYRPS-------AVHEGRTLAPPGRALPQNGS--ADDWVPDQGGPRRGNSTNRRVRLKNPFYPLTQESYGAYAVMCLSVVIFGTGIIGNLAVMCIVCHNYYMRSISNSLLANLAFWDFLIIFFCLPLVIFHELTKKWLLEDFSCKIVPYIEVASLGVTTFTLCALCIDRFRAATNVQMYYEMIENCSSTTAKLAVIWVGALLLALPEVVLRQLSKEDLGFSGQAP-AERCVIKISPDLPDTIYVLALTYDGARLWWYFGCYFCLPTLFTITCSLVTARKIRKAEKASTRGNKRQIHLESQMNCTVVALTILYGFCIIPENICNIVTAYMATGVSQQTMDLLNIISQFLLFFKSCVTPVLLFCLCRPFSRAFMECCCCCCEECIQ---KSSTVTSDDNDNEYTTELELSPFSTI-RREMSTFASVGTHC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O15354-1", "uniprot_id": "GPR37_HUMAN", "id": "O15354-1", "name": "Prosaposin receptor GPR37", "aln": "MRAPGALLARMSRLLLLLLLKVSASSALGVAPASRNETCLGESCAPT-VIQRRGRDAWGPGNSARDVLRARAPREEQGAAFLAGPS--WDLPAAPGRDPAAGRGAEASAAGPPGPPTRPPGPWRWKGARGQEPSETLGRGNPTALQLFLQISEEEEKGPRGAGISGRSQEQSVKTVPGASDLFYWPRRAGKLQGSHHKPLSKTANGLAGHEGWTIALPGRALAQNGS--LGEGIHEPGGPRRGNSTNRRVRLKNPFYPLTQESYGAYAVMCLSVVIFGTGIIGNLAVMCIVCHNYYMRSISNSLLANLAFWDFLIIFFCLPLVIFHELTKKWLLEDFSCKIVPYIEVASLGVTTFTLCALCIDRFRAATNVQMYYEMIENCSSTTAKLAVIWVGALLLALPEVVLRQLSKEDLGFSGRAP-AERCIIKISPDLPDTIYVLALTYDSARLWWYFGCYFCLPTLFTITCSLVTARKIRKAEKACTRGNKRQIQLESQMNCTVVALTILYGFCIIPENICNIVTAYMATGVSQQTMDLLNIISQFLLFFKSCVTPVLLFCLCKPFSRAFMECCCCCCEECIQ---KSSTVTSDDNDNEYTTELELSPFSTI-RREMSTFASVGTHC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F3I2-1", "uniprot_id": "E7F3I2_DANRE", "id": "E7F3I2-1", "name": "", "aln": "----------MEITFLTVFCLFSCCELPTVLTRSNNTTDLPVSSYKVSEIKTLGHEQRGTLN-KTSYIRDKQPTGVISSTRTAGGS--DDTAVTASSR-----LENIDGMKRIGKTTS------FLQGIHKEKQGYQTERATVRNESIMNLSIE-------------SPEYVLERVES------LPKPVAQVQPTDFHPD------FPSIPEWGTSP----LEEYEE--VTAFIPR-------NTRPRTPGVKNPFYPLTGESYGAYAVMCISIFFFTVGIVGNIAIMCIVCHNYYMRSISNSLLANLALWDFVILFFCLPLVVFHELTKDWLLGEFSCKIIPYIEVASLGVTTFTLCALCIDRFRAASNVQMYYEMIENCTSTTAKLTVIWLGALLLALPELLIRQLVKEVSEPPEVTP-CEHCVVRISTDLPDTLYVLGLTYNSARLWWYFGCYFCLPTLFTIISSVVTARKIRKAERASVRGNRKQIQLESQMNCIVVALAILYGFCVIPENISNIVSVYMATGVPRRTLDILHLVSQMMLFCKSAVTPVLLLALCRPFSKAFLDCCCCCFEECGPP--KSSEPNSDDNDQDGTTDLELSPYSTVGRRDASTFPIAGTHC", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q5RGR7-1", "uniprot_id": "Q5RGR7_DANRE", "id": "Q5RGR7-1", "name": "", "aln": "----------MQMLLLRTIFFVAGCPHVLLRGGNRNAHTKETANVTLRSLHDAKASATHPARHQAAGTPAFDTIRQTSGDNSNLSSHLWLLLESKQYGYRHLLSNRTHAVTVSGSNPQKRLRRHKRKKLNGEMPATMGTVAGHNNSKPYSMSKR-ERNHRRKRGTKEHHKKTFKSSKRGPNKSAPPLTPVETYYNALTSSLTMWEPLPKPQALTSTDFPFDLTEFHTKPLDDPWDATPMTPPYAEDEESIFFPNPFYPVTSETYGAYAITIISVLIFAVGITGNIAIMCVVCHNYYMRSISNALLANLAIWDFALLLFCLPLVVFHQLTKTWLLGQFTCKVVPYIEVASLGVTTFTLCALCIDRFRAATNVQMYYEMIENCTSTAAKLAVIWIGALLLALPELLIRQLVSENGDNTVDDPTSERCLIRISTSLPDTLYVLGLTYEGARLWWCFGCYFCLPTLFTIGSSVATARRIRRAERGCARGNKKQIRLESQMNCTVVALAIVYGACVVPENVCNMVSAYMAAGVPQSTMALLHLLSQLLLFLRAAVTPVLLLCLCRPFGRAFLECCCCCCADACGIAAHSSATASDDNEHECTTELELSPFSTM-RREMSNYTATGSHC", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :* : .: . . .* : : . . . . . * . . . * . * . * : .: * : . . . : * : . . *****:* *:*****: :*:.:* .** **:*:**:************:******:*** :::******:**:*** *** :*:**::**************************:************:**:***:***:*********:::*** .* . * .*:*:::**..****:***.***:.***** ************* .*:.***:**:**:...***::**:******* ****:*:** *::***:.*:*:.***:**.: *: :*:::**::** ::.******:.**:**.:**::***** :. :** ****::: **:*****:**: **: *.:. .*:**", "identical_positions": 241, "similar_positions": 130, "identity": "38.68%" }, { "cls_id": "homologset.agr.MGI:1313302", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9PT83-1", "uniprot_id": "E9PT83_RAT", "id": "E9PT83-1", "name": "", "aln": "MSWALEEWKEGLPTRALQKIQELEGQLDKLKKEKQQRQFQLDSLEAALQKQKQKVEDGKTEGADLKRENQRLMEICENLEKTRQKLSHELQVKESQVNFQESQLSSCKKQIEKLEQELKRCKSEFERSQ---QSAEVSLNPCSTPQKLFTTPLTPS-----STYEDLKEKYNKEVEDRKRLEAEVKALHAKKASLPVSQATMNHRDIARHQASSSVFSWQQDKTPSRLSSCSLRTPLRRDVSAAHFLG-EEVTPNKSSVQIGRGDC-SGLPDDPHCSQPLHQAKAQNQELKSKMNELELRLRGQEKEMKDQVNKFQELQLQLEKTKVDLIEKEKILNKTRDEVVRTTAQYEQAAAKCTALEQKLKNLTEELSCHRQNAESAKRSLEQRVKEKEKELREELSRQHQSFQALDHEYTQMKTRLTQELQQAKHSLSVLQLELEKVTSVKQQLERSLEEIRHKFSRAEQALQASQLTENELRRSSEEMKKENSLIRSQSEQRTREACRLEDELGKVKVCLSQSQSFAEEMRAKNTSQEIMLRDLQEKLNQQ--ENSLTLEKLKLALADLEGQRDCSQDLLKKREHHIEQLNDKLNKIEKEFETLLSALELKKKECEELKEEKNQISCWKSENEKLINQIESEKEILLGKVNHLEASLKTQQIS-HDYSERVRTLEMERENLTVEIRNLHSLLDSKMVEIETQKQAYLELQQQSESSDQKHQKEMENMCLKANKLTGQVESLECKLQSLSGEVETKDQQYQDLRMEYETMRDSLQARGSSLVTDEKNQRSSS--------------AFEEQPAVSHSFANLVGEKGSIYSERSDSSVDRGQSPENVAVLQSRVTLLESSLESQNQMNSDLQKQCEELLQIKGEIEENLIKADQIHQNFVAETNQRIGKLQEDAAVHQNIVAETLATLESREKELQLLKEQLEAQQTEVQKLEKNNCLLEGALKELQLLTDTLSSEKKEMNSIISLRKKDIEELTQANGALKEVNEALRQEKMNLLQQHEEITRCVAEGERSIAELSGQYKQERLLLLQRCEETETVLEGLRGDYKAAQENNAKLECMLSECTALCENKKNELEQLKETFAKEQQEFLTKLAFTEEQNRKLVLELETEPQTVRSEITNINKHPVSETDALGQESWSSKEEQKEKQKEVSNLTPENEQLMELTQTKHDYYHLEVEPVENSVKATEEEIRKSSSQYQMDIDTKDISLDSYKAQLVQLEALIKVMEVKLDRSEEEKNSLRQELQTIREELGTKTSQDTQSQARVGLKDCEVEAEEKYVSVLQELSTSQNENVHLQCSLQTAMNKLNELGKMCEVLRVEKLQLESELNDSRSECITATSQMAAEVEKLVNEMKMLNHENALSHGELMKDTADVEFDDKPN-HTSVFLTPLDNS---EQMTSSNKEVRVHFAELQEKFSCLQSEHKILHDQHCEVSSKMSALRSYVDTLKAENSVLSMNLRTLQGDLVKEKEPGAEDGHILPLS-FCRTDSPTLTNFGENSFYKDVLEQTGDTSHLS-LEGNASANPCDVDEVSYSSLEEENLTEKEIPFASLRTVEELEILCQVYLQSIKNLEEKIESQRIMKNKEIEELEQLLSSERKELSCLRKQYLSEKEQWQQKLTSVTLEMESKLAEEKQQTKNLSLELEVARLQLQELDLSSRSLLGTDLEGAVRGPNDGYAIKESEVYISETTEKTPKQDTNQTCDNDVQQDLCLETS-VTETETTRLTGDGCEEQPSKISCEAPAEDRTQDYSECISEL-FSTPSVLVPMDVLEDQGSIQNLHL-QKDTSNENLRLLPEVEDWDKKVESLLNEIKEADSKLSLQELQLKIKIATCIELEKIVKHLKKEETDLSEKLESLPCN-QEVCPRVERS--DLDFNLDMGDDELFRESTKDDAANTEDNYKEKFLDMERELTRIKSEKANIEHHIVSVKANLEVVQAEKLCLERDTESKQKVIVDLKGELFTVISERNRLREELDNVSKESKALDQMSKKMKEKIEELESHQRESLHHIGAVESEVKDKAELIQTLSFSVDELTKDKAHLQEQLQNLQNDSQGLSLAIGELEIQIGQLNKEKESLVKESQNFQVKLTESECEKQTISKALEVALMEKGEFAMRLSSTQEEVHQLRQGIEKLSVRIEADEKKHLSAVAKLKESQRESDSLKDKVENLERELEMSEENQELAILDSENLKAEVETLKAQMDEMAKSLRVFELDLVNVRSERENLAKQLQEKQSRVSELDELCSSLRSLSEEKEQARVQMERDSKSAMLMLQTQLKELWEEVAALYNDQETLKAQEQSLDQPGEEVHLLKSSIQKLKVHIDADKKKQCHILEQLKESKHHADLFKDRVENLEQELMLSEKNKEHLIFQAENSKAEIQTLKTEIQTMDQNLQDLELELTNTRSEKENLMKELKNEQEQISKLETINSSIERLLKDKEQEKVQVKEEARITVEMLQTQLKELNETVVSLCNDQEAYKTKEQNLGSRVQTLELEKAQLLQDLGEAKNKYIIFQSSVNALTQEVEAGKQKLEKEEEEVRTLKEQLKG-QEQLVCKLARVEGEQQLCQKQKLELRSLTMELEQKVKVLQSENDALQTTYEALQSSYKSLEGELGLIKMEKMALVERVNTMTGKEAELQRELHDVEQKSTQLKEEYSKEKTRLTEDLEVVMEELKN-----------------------------------------------------------------------------------------------------------------TKVAHLKNVNHLEKEFQRAQGKIKLLLKSCKQLEGEKKMLQKELSQLEAAQ-KQRAGGWSWGSLVDSNVDELMTENKELKETLEEKIKEADKYLDKYCSLLISHEELEKTKEILEIQVARLSSRQNKQDLQSSPLLDSSVAGPSPSTSVSERKSTSGLNKTLGKRQRSSGIGENGNGTAPSTPETFSKKSRKSVSNSAHPAEDEEETEFEPEGLPEVVKKGFADIPTGKTSPYILRRTTMATRTSPRLAAQKLLGSSPTLGKENLVESSKPTAGGSRSQKVKVVQESSMDAHAVFQELPAKSLTANNMPGRNSTESPREG-LRAKRACPASSPAAGPDPMNNENCRVQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q3P4-1", "uniprot_id": "E9Q3P4_MOUSE", "id": "E9Q3P4-1", "name": "", "aln": "MSWALEEWKEGLPSRALQKIQELEGQLEKLKKEKQQRQFQLDSLEAALQKQKQKVEDGKTEGADLKRENQRLMEICEHLEKSRQKLSHELQVKESQVNLQESQLSSCKKQIEKLEQELKRCKSEFERSQQVAQSADVSLNPCSTPQKLFATPLTPS-----STYEDLKEKYNKEVEERKRLEEEVKALHAKKVSLPVSQATMNHRDIARHQASSSVFPWQQENTPSRLSSDALKTPLRRDGSAAHFLG-EEVSPNKSSMKTGRGDC-SSLPGEPHSAQLLHQAKAQNQDLKSKMTELELRLQGQEKEMRSQVNKCQDLQLQLEKTKVELIEKERILNKTRDEVVRSTAQYDQAAAKCTTLEQKLKTLTEELSCHRQNAESAKRSLEQRIKEKEKELQEELSRQHQSFQALDSEYTQMKTRLTQELQQVKHLHSTLQLELEKVTSVKQQLERNLEEIRLKLSRAEQALQASQVAENELRRSSEEMKKENSLIRSQSEQRTREVCHLEEELGKVKVSLSKSQNFAEEMKAKNTSQEIMLRDLQEKLNQQ--ENSLTLEKLKLALADLERQRNCSQDLLKKREHHIDQLNNKLNKIEKEFETLLSALELKKKECEELKEEKNQISFWKIDSEKLINQIESEKEILLGKINHLETSLKTQQVS-PDSNERIRTLEMERENFTVEIKNLQSMLDSKMVEIKTQKQAYLELQQKSESSDQKHQKEIENMCLKANKLTGQVESLECKLQLLSSEVVTKDQQYQDLRMEYETLRDLLKSRGSSLVTNEDNQRSSEDNQRSSEDNQRGSLAFEQQPAVSDSFANVMGRKGSINSERSDCSVDGGRSPEHIAILQNRVTSLESSLESQNQMNSDLQMRCEELLQIKGEVEENLSKAEQIHQNFVAETNQCISKLQEDAAVHQNIVAETLATLESKEKELQLLKEKLEAQQTEVQKLNKNNCLLEGTLKELQLLSDTLSSEKKEMNSIISLSKKNIEELTQANEALKEVNEALEQEKMNLLQKHEKITSCIAEQERSIAELSDQYKQERLQLLQRCEETEAVLEDLRGNYKTAQENNAKLECMLSECTALCENRKNELEQLKETFAKEQQEFLTKLAFAEEQNRKLMLELEIEQQTVRSEITNTNKHSMSATDGLRQECLTLNEEQNEQQNEVSNLTHENEQLMELTQTKHDSY-LAVEPVENSVKATEDEIGKSSSQYQMDIDTKDISLDSYKAQLVHLEALVRILEVQLDQSEEENKKLHLELQTIREELETKSSQDPQSQARTGLKDCDT-AEEKYVSMLQELSASQNENAHLQCSLQTAVNKLNELGKMCDVLRVEKLQLESELNDSRTECITATSQMTAEVEKLVSEMKMLNHESALSQNELMKDTSGGEFHDKAN-HSSVFLTPLDSSNFCEQMTLSSKEVRVHFAELQEKFSCLQSEHKILHDQHCEVSSKMSALRSYVDTLKAENSALSMSLRTLQGDLVKEGEPAAEGGHGLPLS-FCGADSPSLTNFGETSFYKDVLEQTGDTCHLS-LEGNASANSCDLDEEFSSSLEEETLTEKESPPAPGRTVEGLEVLCQVYLQSLKNLEEKTESQRIMKNKEIEKLEQLLSSERKELSCLRKQYLSEKEQWQQKLTSVTLEMESKLAEEKQQTKTLSLELEVARLQLQELDLSSRSLLGTDLESVVRCQNDNYDIKESEVYISETTEKTPKQDTDQTCDKDIQQDLGLETS-VTESETTRLTGEGCEEQPPKTNCEAPAEDKTQDCSECISEL-CSSSNVLVPMDVLEDQGSIQNLQL-QKDTLNENLRLLPEVEDWDKKVESLLNEIMEADSKLSLQEVQLKMKIATCIQLEKIVKDLRKEKADLSEKLESLPCN-QEVCLRVERSEEDLGFNLDMGANELLSKSTKDNATNTEDNYKEKFLDMERELTRIKSEKANIEHHILSVETNLEVVQAEKLCLERDTESKQKVIIDLKEELFTVISERNRLREELDNVSKESKALDQMSKKMKEKIEELESHQRESLRHIGAVESEVKDKADLIQTLSFNVGELTKDKAHLQEQLQNLQNDSQELSLAIGELEIQIGQLNKEKESLVKESQNFQIKLTESECEKQTISKALEVALKEKGEFAVQLSSAQEEVHQLRRGIEKLSVRIEADEKKHLSAVAKLKESQRESDSLKDTVETLERELERSEENQELAILDSENLKAEVETLKAQKDEMTKSLRIFELDLVTVRTERENLAKQLQEKQSRVSELDERCSSLRRLLEEKEQARVQMEEDSKSAMLMLQMQLKELREEVAALCNDQETLKAQEQSLDQPGEEVHHLKSSIRKLKVHIDADEKKHQNILEQLKESKHHADLLKDRVENLEQELILSEKN---MIFQAEKSKAEIQTLKSEIQRMAQNLQDLQLELISTRSENENLMKELKKEQERVSDLETINSSIENLLKDKEQEKVQMKEEAKITVEMLQTQLKELNETVVSLCNDQEVSKTKEQNLGSQVQTLELEKAQLLQDLGEAKNKYIIFQSSVNALTQEVEAGKQKLEKGEKEIRTLKEQLKS-QEQLVCKLAQVEGEQQLWQKQKLELRNVTMALEQKVQVLQSENNTLQSTYEALQNSHKSLESELGLIKLEKVALVERVSTISGKEAELQRELRDMLQKTTQLSEDYNKEKNRLTEEVEVLREELQN-----------------------------------------------------------------------------------------------------------------TKAAHLKSVNQLEKELQRAQGKIKLMLKSCRQLEGEKEMLQKELSQLEAAQ-QQRAG-----SLVDSNVDEVMTENKALKETLEEKVKEADKYLDKYCSLLISHEELEKAKEILEIEVARLKSRQSRQDLQSSPLLNSSIPGPSPNTSVSEMKSASGQNKASGKRQRSSGIWEHGKRAAPSTAETFSKKSRKSDSKSTRPAEHEQETEFEPEGLPEVVKKGFADIPTGKTSPYILRRTTMATRTSPRFATQKLVGSSPSLGKENVVESSKPTAGGSRSQKVKVVQESSADSHTAFQELPAKSLTASNIPGRNSTESPREG-LRAKRAYPASSPAAGPDPTNNENCRVQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49454-1", "uniprot_id": "CENPF_HUMAN", "id": "P49454-1", "name": "Centromere protein F", "aln": "MSWALEEWKEGLPTRALQKIQELEGQLDKLKKEKQQRQFQLDSLEAALQKQKQKVENEKTEGTNLKRENQRLMEICESLEKTKQKISHELQVKESQVNFQEGQLNSGKKQIEKLEQELKRCKSELERSQQAAQSADVSLNPCNTPQKIFTTPLTPSQYYSGSKYEDLKEKYNKEVEERKRLEAEVKALQAKKASQTLPQATMNHRDIARHQASSSVFSWQQEKTPSHLSSNSQRTPIRRDFSASYFSGEQEVTPSRSTLQIGKRDANSSFFDNSSSPHLLDQLKAQNQELRNKINELELRLQGHEKEMKGQVNKFQELQLQLEKAKVELIEKEKVLNKCRDELVRTTAQYDQASTKYTALEQKLKKLTEDLSCQRQNAESARCSLEQKIKEKEKEFQEELSRQQRSFQTLDQECIQMKARLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNIKQCLNQSQNFAEEMKAKNTSQETMLRDLQEKINQQ--ENSLTLEKLKLAVADLEKQRDCSQDLLKKREHHIEQLNDKLSKTEKESKALLSALELKKKEYEELKEEKTLFSCWKSENEKLLTQMESEKENLQSKINHLETCLKTQQIKSHEYNERVRTLEMDRENLSVEIRNLHNVLDSKSVEVETQKLAYMELQQKAEFSDQKHQKEIENMCLKTSQLTGQVEDLEHKLQLLSNEIMDKDRCYQDLHAEYESLRDLLKSKDASLVTNEDHQRSLL--------------AFDQQPAMHHSFANIIGEQGSMPSERSECRLEADQSPKNSAILQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKGEIEENLMKAEQMHQSFVAETSQRISKLQEDTSAHQNVVAETLSALENKEKELQLLNDKVETEQAEIQELKKSNHLLEDSLKELQLLSETLSLEKKEMSSIISLNKREIEELTQENGTLKEINASLNQEKMNLIQKSESFANYIDEREKSISELSDQYKQEKLILLQRCEETGNAYEDLSQKYKAAQEKNSKLECLLNECTSLCENRKNELEQLKEAFAKEHQEFLTKLAFAEERNQNLMLELETVQQALRSEMTDNQNNSKSEAGGLKQEIMTLKEEQNKMQKEVNDLLQENEQLMKVMKTKHECQNLESEPIRNSVKERESERNQCNFKPQMDLEVKEISLDSYNAQLVQLEAMLRNKELKLQESEKEKECLQHELQTIRGDLETSNLQDMQSQEISGLKDCEIDAEEKYISGPHELSTSQNDNAHLQCSLQTTMNKLNELEKICEILQAEKYELVTELNDSRSECITATRKMAEEVGKLLNEVKILNDDSGLLHGELVEDIPGGEFGEQPNEQHPVSLAPLDESNSYEHLTLSDKEVQMHFAELQEKFLSLQSEHKILHDQHCQMSSKMSELQTYVDSLKAENLVLSTNLRNFQGDLVKEMQLGLEEGLVPSLSSSCVPDSSSLSSLGDSSFYRALLEQTGDMSLLSNLEGAVSANQCSVDEVFCSSLQEENLTRKETPSAPAKGVEELESLCEVYRQSLEKLEEKMESQGIMKNKEIQELEQLLSSERQELDCLRKQYLSENEQWQQKLTSVTLEMESKLAAEKKQTEQLSLELEVARLQLQGLDLSSRSLLGIDTEDAIQGRNESCDIS--KEHTSETTERTPKHDVHQICDKDAQQDLNLDIEKITETGAVKPTGECSGEQSPDTNYEPPGEDKTQGSSECISELSFSGPNALVPMDFLGNQEDIHNLQLRVKETSNENLRLLHVIEDRDRKVESLLNEMKELDSKLHLQEVQLMTKIEACIELEKIVGELKKENSDLSEKLEYFSCDHQELLQRVETS-EGLNSDLEMHADKSSREDIGDNVAKVNDSWKERFLDVENELSRIRSEKASIEHEALYLEADLEVVQTEKLCLEKDNENKQKVIVCLEEELSVVTSERNQLRGELDTMSKKTTALDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRVENLERELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNELQKEQERISELEIINSSFENILQEKEQEKVQMKEKSSTAMEMLQTQLKELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQD-QEQLVSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKTAELQEELSGEKNRLAGELQLLLEEIKSSKDQLKELTLENSELKKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKKHQALLLDTNKQYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEELKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEKQKTG-----TVMDTKVDELTTEIKELKETLEEKTKEADEYLDKYCSLLISHEKLEKAKEMLETQVAHLCSQQSKQDSRGSPLLGPVVPGPSPIPSVTEKRLSSGQNKASGKRQRSSGIWENGRGPTPATPESFSKKSKKAVMSGIHPAEDTEGTEFEPEGLPEVVKKGFADIPTGKTSPYILRRTTMATRTSPRLAAQKLALSPLSLGKENLAESSKPTAGGSRSQKVKVAQRSPVDSGTILREPTTKSVPVNNLPERSPTDSPREG-LRVKRGRLVPSPKAGLESNGSENCKVQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1Q7X5-1", "uniprot_id": "F1Q7X5_DANRE", "id": "F1Q7X5-1", "name": "", "aln": "MSWAVEEWKDGLPAKALQKIQEIEAQLDKLKKERQQKQFQMDSLEATLQKQKQKMDSEKSEASALKRENQSLVESCEHLEKARQKLTHDIQTKEQQVNYLEGQLNSFKKQTDRLEQEVKKYKHELERSQ---TSHASEIQQLSTPQKTFATPATPNHWQQDSKITDLQEKYNREVEERKKLEAEIKVMHVKLLNQ----SSVSHKDIARQQTGSSIFPWQQDQKSSHQSLPVMETPSRRRNGASGMPWSYDDTPIKPHQQFT-----SGAPSDTVGSQQMEQLKNINQDLRSKVSELELRLQAHEKDMKNQINKFSEIQSQLEMAKKDVAEKDKLLNKSRDELTKATGQYEQSVSKCSAFEIKLKQVTEEMNCQRHNAESMHRSLEQKIKDQERESQKELAQLQSSYQALDQQFTQVKNKTSMEIQQAKKDHNVLQSEMDKVTALKNRLEKELEELKQKLLRSEQALQASQVKEAETKKKFEEMQREKNTLNCQLDQGMKRVKQLEDEKQNTEQILAKNRMMVDDLKVKTQTQNEELTELRKKMDHQSVSSAQELENLKKTLIEAEAKNMKTQAELQKLVHDVELKENKICAVEKENEELKMTSNSCQKELAEMKKEYDALLQWKTEKEQLINNAESNRNELLAKVADLEKDKDNLSNAHGDLQKKMQDLENEKIGLSGQIDSLKGELLVKCVELEEKGRVYEELQQQFGETKIKHKKEMDNLNQQITLTQGKVSELEAKLLQETSKLEGMEQAHGQLLAEYESACILAMSKDSIIEMNKTEIVHLQES---------FTLRDQELEKFKVEKDILAKECEDRLAQNKELEQQKLNTETSLMEVLAKFTLLESDLRCQKDLNAEIQGKYDELSKIKEDLVEKVSSLEKREKDLINEVESLLQKNKSLCSLEEQFNCLVAEAEETR-SSLEKVKELQVQTTTELENQKTIAENLAIDLEEEKKKALSIKQENTQLKVKQEEIENKANDLFEKYESLQKLHDAVCQENANHLKEISIVTEALAEKD-AMAERIALIKTELETSNNLSATLKNSLENLQTQFDSSVELISSLEKKLHDMSDEKSLLEISIKELTERHNKESEVYVSELETHIKKHKSLEEHISVLETELQNKSLETKTAS-EKLEVTTQEMIKLKQDFSLSENKLSVVTDSNKKVAKELEDMKQNVFLQEQEMEG-------------------------------------------LRLALSDLKNQEAAKSCEIETLKEKLQKAQSEHAKTS-------------ETLNEKNINMSKIKVQLEMLQMDLEDNENCINAFDAQVEELQGNVSILEAKLSESEAQRSNLESKLESVKEDYVKSSLEVSQLSACLEESQKEQQS----------RSVLVAELESLRVIHEQLKVSLEQENCKQANLEAMYTNLMDQKLKLESEIQELKADTQGSQKQIDQLKQANDRLASQIAEQQ---IHIEQLQSEKNLADTLNKEQTSGGNDQDICEMPFANTSLLPFEEDTAILG--MSSPKGKHDSQEEPKTPLSAEEDYKDFALQEQMQNKSSDIEDMSHVLKETVRTMEEQTAIQ---------------------IEQLKLQHATELQSMEEQMLNIKNELEAKLKEEKQHTEILSSQLEATMQQLQELDIASSSLLAADTSQNMG-----------------------------------------------------------------KFASGAQDDLIHHTEQSNSTLGIITESEHSNLETETLKEVLRKREEELLHLQSQFEVLESEMVIRKDLCLDMEGKICKMESEKTNGTDKLASIIQENEKLNKHIGELKEEIDSLTLQLQTSNCQLTDVMEMMESL------------------------EMAKGEWNEKFFQIESELKRVRSEKANLEKHILSMEADIEEMQEQKQKQEAELETARRTNCSLEQQLNITMAEGGRLKEELILCTDERESETHSLMKLKEKADLLEKRETDTKELIKELEDDIRVGKKQNEVASDQISVLLKEKEQLIQQSQNLENKIVLLNEDNERLLSELNDIKHNDSFTSRETENMSSKIHSLEDENVRLSQSLEMSLLEKGEIASRLISTQEEVAQMRQGIEKLKVRIESDERKKNHMSQLLKAAQRKADVLQDNIEKLEREKELSEQNLEDAILQAETAKAELEEIQAETQDLTKKIEEMTSELKDLKEEKYKLEQELDQKNKLIEELQLSIQEASVKLKSAEEATLNQEQ-----------------------------------------------------------------------------MIKDFQFKVGAMEEELRLFQTEVESKEVKALELASHLLSLESENKEFAQRVLEYERSQEELHSSNQSLLKDFESKQQELSEENTQLRSQIAELQALSLIREEQDEE-------LQKDKVELQSTIAQLEEKTQMQSTKMEVMQNSISSLEINIQQLEGQLDAMKLMNVELTGKLNSLQESSLHLETQHKQELCEAKEIQNALEINQNLLTCQLQESQKQIEEYKFSLEALAAEKDGLQKSISVIQESHDVQLK--ENNMRHEENLKRTQQQLEVELNALKENILVAEKNAAQYQSDLESIKSQNAEKDSALKELQNKWENCQK-------------------------------------------------------------------------------------------------------------------------EKAELDSKITRLSKEKDSAMSKINLWMKSCKQLENEKQTLQEELQQQGQEIETLKAS--KEQAEGSSSSGALQEELEELKEALEEKSREADDSMDRYCSLMVKVHKLEDSNESLKNQLKQLSTQTKTPKSRRS-----------LRSETSDLENSNPEGVTSGKRQRAIDDTPN------KAQEALHNITKRLKAAAATPKAKQDDEDFRPEGLPELVQKGFADIPVGEMSPFIVRR-TTAQRCSPRLAARTTAVLQSSGSAEHPAQISMQTAEGRTPNTVQKPKATPSRNVPLLSTLTNSPLKNSCERLAPVIEQKISRRSRSFKNSPQTSEQVTASPKQNDNCQVQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1PZT6-1", "uniprot_id": "A0A8M1PZT6_DANRE", "id": "A0A8M1PZT6-1", "name": "", "aln": "MSWAGDDWTVGLTGHVLQKVKQLLAQNEKLNKEKQQRQLQLDNSEVALHKQKQKHEEVRVELAAVQRELGGVREAAQAEVRTRERLSHDLQVKTGQVHSLEGQLESAKKLTQSLTQEIKRLEAELEKLQK--GNGSGESTLFSTPCWNTSSPWDNN--------------------GGFRAESESKAQHAR--------QQLQFGDVPKPSAGGASSPFPQQ--------PYKSPPLRRHVRQSEPSTPSSVFPWERDVLWSTPKGRPTSLVSSSEVMIKSSNCGMEDALRNEIDELRVRVSDLQREAQLETERMKDVESRLAQANREISSKEQSLTRTQEQLTRAQTRSTQETDRAQTAEQKVKHLQEELKCQRQNAESSRCNAEQRRKDMEREHQRELVEQQRERQALEKQHQQENNRLNQEIQQARTLHNTLQAQHDKVCLQKQSLERDLEDVKGKLKNTEADLKESQKREAQTEAKLTEALRECESLTVSLGQMKKQEKVLQEEVKRLTEELAEALKLIKELQAQLAAPPPPVAAPNFSSAGDSFSPCVSLHHDRSSPFNNSSQRKRAPNTGRTR--------------------------------------------------------------------------------------------------------------------EEERMKYPSGREPGEGIDSEHIEKFE----------------------------------------------------------------------------------------------------------SEEKSQKRKGVQTLPIGSLKLTEFDLDTS----------------------VMEQDTGIEDVDTDSFTSDSTRGTMPKSESDISR--------------------SLKLDNTSGKTEKYDS----------------------------------TTLKDLKKQNAELQDELRDVKYDLQKRLEDLETQRRAETEARTKLKQLSRKHSTQTEQQRAKALELKDSLVKLETQLEQEKKESSKLKETLHALQSEAENRKVNDQEEDSQLKKALAEMEQKETIMEEEMMGIKKELQDLQLKLAQEREEREQERLEERKLIRRE---EGLKIAQLQEELDILRKSTSLEVKISKDNLPLTYLHLEHHQN-------------------------------------------TDQKADLTENKDLIPSPGVQEFSVNLQNTIVRN--------------------------------------------------EAKTIELIMDLEAQTKPKTSPSDMNRARALSTEASDLDNSTVLVLEVERLRAARDRE-------------------------------------SEKAKVSQRKLEELQKQVTTQTKQLTQAFESQSKHIDNLLSELEDKECALQKQAEELQKCQEKICFLEEKQTR---------------------------------TNDLSVPPELSTEISRELSCDSVFSNTSISDHEMFSDDTPPVLKEKVS------------------------------------------------------------ELTVQLPVEASVSQNIDQTNTSEISDKLQATENFKQQSLDTSNSSTASDAP--------------------------------------------------------------------------------------------------------------------------------------------IISDVTEEKSSSVLQDEQLNVVNCQNDIPEHSIHDIK------------------------------------------------------------------------ELERVTKELQAAQLELNVMKAQNSELALQRD---------MIKDKLLNVQQENQELKSTLKHLCEDTGAKQDGALNLANSKNKSLLSSNEGLQSISPLG-----------------------KEKLVVQHGNSEAEVQSLQEQIQKLQDQIRDLSEQN-----RTQAEQLELWKLSTVEETAGNNSPSIVLKEFELFLPCGSRKLHTHSQTR-----------TMMHQCDVRDVTYHSGLDDSNLTNSDEKVSSETQIT--------IDVENSQGPAEDIMARNKKLLT--------------------------------------------------------------------------------------------------------------------------------------------------------------------KDNAQHKCENSSANHYCHKSPPVCISDIMTSNTRDKLSPLLTKPTDYSHSESQPVASLS----------------------------PEGQPKVTDASANSQEDALISVSISTKYQAEVINTNAITESYGNADFHNSETMGTVALDKHRGDATDKQNKHYTAVENTIRNESAQGQKAEVSGVYKRTG-----------------------------------------------------------------VISVSTQTEESREMHLAVKQPP---------------------------------------------------------------------------------------------------------------------------------------------------------------------VHACTQTDGEQLQTEQDEGD---------------------------------KASVDSPALSPTPHTVTNQLLLSSVFPMSDP----------------------------------------------------------------------------AHLAERIRQNRNRMSAAYDETEYEPYGLPEVVMKGFADIPSGPACPYVLRRGLLGTDAMPLPRRGEATPLEEDDDIEP------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**** ::*. **. :.***:::: .* :**:**:**:*:*:*. *.:*:***** :. : * : ::** : * .: :::::::*::*.* **: *.**.* ** : * **:*: : *:*: * . . .** ::* . : * * *. :.: :.. *:.: .:..: .: *: .* ** : . * . . .. . :: *:.:: **.:*: ::: : : :: .::: :* :: :: .*:: *.: ::::.:: : * : : * *:* : *::.*:*:**** : . **: *: *:* :.** . : . *:*: : * : : . *:**.: ..** : :*: *: **..**:.: *: .:* :: ** * : . . * :* . : * :. *: * . * : : .:::.: : : . . : . . *.: : : : . :. : :. : : * . :: . :* :::: .: : . :. :: . : *: :. . . . . . :. . . : :: .. ::* : *:. : : : ::. . * : : . : . * . . : :.*: * . : . :: . * : :. : .:. : .: : : . :* . ::::. : ... : : * : .. . :::. :: : .* . .. : : .: . * : . :. . . . :: . :*: : : * . . . . . . :: : : .: * : . * . . : . . :. . . : .: * . . :: :*. :* :*:.: * :* * . * : ..: : .*. :* :: : .:: . *:.. * . :: :: * .: : : :: :* . * .*: * .. : . :: :. : . : . * * :* : . : . *. .* :: ::..:. .:: . .: . . : .: : :: *: * : .. . : :: . . * :. *.:. * : : :: *. :. * : :. ..: : .. ::. : : . . .:.* : . : . . * * : :. . : : . . :: : . . ..: . . : :: ::: *: .. : . . :: . ::. .: . :::* * : *: ::: : * :::. .. *: . :... : :.: : ::.* ****:* ******* * .*:::** . * . * ", "identical_positions": 187, "similar_positions": 561, "identity": "5.96%" }, { "cls_id": "homologset.agr.MGI:1313312", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9W240-1", "uniprot_id": "Q9W240_DROME", "id": "Q9W240-1", "name": "K Homology domain-containing protein", "aln": "------------------------------------------METPSELTEKQNQDQ-----PTYQPRLNEVAQKFLADLDAERKRLSAEFPLCALLIDESVDRVYSTGRIPGKE-PFADVYQQKPMKIIQKVFVPVNKFPKFNFTGKILGPKGNSLRRLQEETHCKIVIKGRNSMRDRNKEEELRSSGDPRYAHLHKDLFLEVSAVAPPAECYARIAYALAEIRKYLIPDDNDDVWHEQQRELMEM--------NPKSAKKSNGLN---------------------MAPYRSNFDKAIGA-------------------IRNRAPKYNNQIRRVTENPREVAYMEEVEYDYDEHLMFCS---------------------PVVRL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W224-1", "uniprot_id": "Q9W224_DROME", "id": "Q9W224-1", "name": "", "aln": "------------------------------------------METQSEFTEEQNQDQPTQDQPTYQPRLNEVAQKFLADLDEERKRLSAEFPLCALLIDESVDRVFSTGRIPGKE-FYADVYHQRPMKITQKVFVPVNKFPKFNFARKILGPKGNSVRRLKEETNCKIVIKGRSSMRDRNKEEELRSSGDPRYAHLHKDLFLEVSAVAPPAECYARIAYALAEIRKYLIPDDNDDVWHEQQRELMEM--------NPESAKKSNGLN---------------------MAPYRSIFDKTIGG-------------------NRNGAPKYNNQIRRVTENPREVADMEEVEYDYDEHRMPPSRPSLGFEYSKPPPSMTATNATPFKRAYP--YPTDMNR----------------TREPPIKSYKPNPYTILNKYINN-----------------------------------------RAPSDFVAQRYN----------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W2D0-1", "uniprot_id": "Q9W2D0_DROME", "id": "Q9W2D0-1", "name": "K Homology domain-containing protein", "aln": "---------------------------------------MEKMENPSEITEEQPTTT-----HEYQPRLNEIAQKFLADLDEERQRLSAEFPLCALLIDEARDRVYATGRIPGKE-LYADVYRQKPMKIIQKVFVPVNQYPKFNFAGKILGPKGNSLRRLQEETQCKIALKGRSSMRDRNKEEELRS--DPRYAHLQKNLFLEVSTVAIPAECHSRIAYALAEIRKYLIPDNNDEVSHEQLRELMEI--------DPESAKNFKGLN---------------------LEAYRSVRD-------------------------SNGASKYINLIKRVAENPSKVADMEQVDYDYDEHHMPPIHLPTGYEYSIQRPS---KIVAKFKRPYP--YPTDMKP----------------VREPPIKFYKPNPG--IGTYVMK-----------------------------------------SMLG---AQ-------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W254-1", "uniprot_id": "Q9W254_DROME", "id": "Q9W254-1", "name": "", "aln": "MAENGLRVPGSSAVASAVASTATGVGGGSAAGTAGAGTGVVPTGVSGGTSNGEHENEHNANADGEKAQPAPAVQKYMQELMTERSRMENHFPLAVKLIDEALERVQLNGRIPTRD-QYADVYQQRTIKLSQKVHVPIKDK-KFNYVGKLLGPKGNSLRRLQEETQCKIVILGRFSMKDRAREEELRNSADAKYAHLNLPLHVEVSTIAPPAEAYARVAYALAEIRRYLTPDKHDDIRQEQYRELME---------DPEAAKKLTLRQ---------------------LQQQSNAAASGAGGGGGGGGGNGNGGAAGSGSNNGNGNQRSGGNYRQKFQQQSHYRHNEETVYFRSHNNAYHQPKPYVPAAQRGNAMHTTLPPQAIVRASPPGMVVSAAS----------------FNGRNAGLGNAGGGGIMANSIVA-----------------------------------------TTGGGIGGAVPPNMRYRPAAPYQFVKK-------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W255-1", "uniprot_id": "Q9W255_DROME", "id": "Q9W255-1", "name": "", "aln": "--------MPRDYDRD-----YNEDAADYKRKRRDE--EPAATGAPETPEADGGGHTTSHAALRDTPQLNEKTNAYLQECLLEKKTLEKKHIITKRLLDDEVEKILVSGRIPKPE-IYANVYSEKPIRVAQKVLFPIKEYPKFNFVGKILGPKGNTLRQLQEETMCKMVVMGRNSMRDHGKEEELRSSGNPKYAHLSRDLHVEISTVAPPAEAYHRISYALGEIRKFMIPDANDDIRLEQLREMDG---------KERMYKKSHHYS-----------KSYG-----DHGAYSSRTPPPASS------KPKVYSILEKARYVMDDPN-YGIVKTHRSRDHELYD--HHGEYDRYATPPPQ--------TSKHSTHHAQYDSSSYERDY-RREYHPHS-----------------SSSSYAAAYPAKPSNGRSSSSYR-----PTTSGSG--------------------------SHSSAHYETGSRSRESVRYRSAPYPKIR---------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A0B4KFT9-1", "uniprot_id": "A0A0B4KFT9_DROME", "id": "A0A0B4KFT9-1", "name": "", "aln": "--------MTEKYDGNGDFSAFNDDDNDFGGKPRKPGGSIGAPGGAHNGDASAHDHGHHGGDPGGNVQINEKANEYIRDCMAERNRMDRKFPIAEKLLEGEIEKVQTTGRIPSREQKYADIYREKPLRISQRVLVPIREHPKFNFVGKLLGPKGNSLRRLQEETLCKMTVLGRNSMRDRVKEEELRSSKDPKYAHLNSDLHVEISTIAPPAEAYARIAYAMAELRKYLIPDSNDIIRQEQLRELMDSTSLNDNDNAKSGYKKTSHMQGGNNVLGGGSINPIGGVKNTPHHSYRSSQPSSFSKNVLAP-KQKVMSILEKARTAMDETYGRGYDDGLGYDPHQSYDSYSYGTHGHGPHGPPANILGGVGGISGGGGRGGHYESSDYEPDYGRREYYQHSPGYSAGGGGGVGLGTGGASQSNAIGGSGLSSNHNRSHVNRXNLLDPSSASGGRGTNPAATTQNLTMKSQPNSSNNFLPNHGASECQNGKNINPNYYYNSNGSSKVNQQQLQQSQPNLPPQLSGHNNNSSNGSRASNMINTSSHNNCNSNFHPVGEKNSNDVSFISSYRLGPMDGQKSANSNNINNHTLGSKNHSNNTTTTASVPNMLLVRPANPSLHIGTFPFLPVQFF------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9JLP1-1", "uniprot_id": "KHDR3_RAT", "id": "Q9JLP1-1", "name": "KH domain-containing, RNA-binding, signal transduction-associated protein 3", "aln": "-----------------------------------------------------------------------MEEKYLPELMAEKDSLDPSFTHALRLVNREIEKFQKGEAKDEEK--YIDVVINKNMKLGQKVLIPVKQFPKFNFVGKLLGPRGNSLKRLQEETLTKMSILGKGSMRDKAKEEELRKSGEAKYFHLNDDLHVLIEVFAPPAEAYARMGHALEDIKKFLIPDYNDEIRQAQLQELTYLNGGSENADVPVVRGKSTLRT---------------------RGVTTPAITRGRGG-------VTARPVAVGVPRGTPTPRGVLSTRGPVSRGRGLLTPRARGVPPTGYRPPPPPPTQETYGEYDYDDGYSTAYDDQSYDSYDNSYSTPAQS-----------------GADYYDYGHGLGEEAYDSYGQE--------------------------------------DWTNSRHKAPSARTAKGVYREQPYGRY----------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R226-1", "uniprot_id": "KHDR3_MOUSE", "id": "Q9R226-1", "name": "KH domain-containing, RNA-binding, signal transduction-associated protein 3", "aln": "-----------------------------------------------------------------------MEEKYLPELMAEKDSLDPSFTHALRLVNREIEKFQKGEGKEEEK--YIDVVINKNMKLGQKVLIPVKQFPKFNFVGKLLGPRGNSLKRLQEETLTKMSILGKGSMRDKAKEEELRKSGEAKYFHLNDDLHVLIEVFAPPAEAYARMGHALEEIKKFLIPDYNDEIRQAQLQELTYLNGGSENADVPVVRGKSTLRT---------------------RGVTTPAITRGRGG-------VTARPVAVGVPRGTPTPRGVLSTRGPVSRGRGLLTPRARGVPPTGYRPPPPPPTQETYGEYDYDDGYGTAYDEQSYDSYDNSYSTPAQS-----------------AADYYDYGHGLSEDAYDSYGQE--------------------------------------EWTNSRHKAPSARTAKGVYRDQPYGRY----------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75525-1", "uniprot_id": "KHDR3_HUMAN", "id": "O75525-1", "name": "KH domain-containing, RNA-binding, signal transduction-associated protein 3", "aln": "-----------------------------------------------------------------------MEEKYLPELMAEKDSLDPSFTHALRLVNQEIEKFQKGEGKDEEK--YIDVVINKNMKLGQKVLIPVKQFPKFNFVGKLLGPRGNSLKRLQEETLTKMSILGKGSMRDKAKEEELRKSGEAKYFHLNDDLHVLIEVFAPPAEAYARMGHALEEIKKFLIPDYNDEIRQAQLQELTYLNGGSENADVPVVRGKPTLRT---------------------RGVPAPAITRGRGG-------VTARPVGVVVPRGTPTPRGVLSTRGPVSRGRGLLTPRARGVPPTGYRPPPPPPTQETYGEYDYDDGYGTAYDEQSYDSYDNSYSTPAQS-----------------GADYYDYGHGLSEETYDSYGQE--------------------------------------EWTNSRHKAPSARTAKGVYRDQPYGRY----------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W249-1", "uniprot_id": "Q9W249_DROME", "id": "Q9W249-1", "name": "K Homology domain-containing protein", "aln": "-----------------------------------------------------------------------------------------------METKAGLSALEERSLKGSEKLKMLDITRDKPVKVAVKVAVPVRDHPKFNFVGKLLGPKGNSMKRLQEDTMCKMAVLGRGSMRDRRKEEELRGSGDSRYAHLFEDLHVEISTFAAPAEAHARIAYALAEVRRFLVPDYHDDIRQEQMWEMQALTSTPALGAHSLEDSHSPTINS-----------------SSQVGGTTNSSSNGASGRGLGGGLADMDTSNDDKSDDASGMECLSAVDKLDCSSSCASLGISGITTISTTSPEHPHPHQHHQQHQQHQQHHAHLHPAHAHGNQQQQQQVQHHHSHQAHFHQLLQQAHGGASAAAAACGEHLSGQTTPATAAALHT----------------------------TAMAVALQHQLTAAGIGGLLKPATGVGATMAGLPTTQAGAAALQLPGDGESSGSTLTLLEPPGTALLHPALRNVKTINIGGGLGRKRPLLGVPRSGMNPTKRTVMSLLARAKNSQALHSVRQPMVTATSFAEPLQMLASPFIIPHRAVDQPILALSKESLAQGV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . . :: :: ::: :* .*:.. ***:. *:***:**::::*:*:* *: : *: **:*: :***** :.:* ** *.: :...* ***.: *:.:*: :::::: ** :* : * *: : ", "identical_positions": 39, "similar_positions": 57, "identity": "6.17%" }, { "cls_id": "homologset.agr.MGI:1313314", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XIT8-1", "uniprot_id": "Q5XIT8_RAT", "id": "Q5XIT8-1", "name": "Claudin", "aln": "MASMGLQVLGISLAVLGWLGVILSCSLPMWRVTAFIGSNIVTAQTSWEGLWMNCVVQSTGQMQCKMYDSMLALPQDLQAARALMVISIIVGALGMLLSVVGGKCTNCME-DETVKAKVMITAGAVFIVASMLIMVPVSWTAHNVIRDFYNPLVASGQKREMGASLYIGWAASGLLLLGGGLLCCNCPPRRNEKPYSAKYSAARSVPASNYV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35054-1", "uniprot_id": "CLD4_MOUSE", "id": "O35054-1", "name": "Claudin-4", "aln": "MASMGLQVLGISLAVLGWLGIILSCALPMWRVTAFIGSNIVTAQTSWEGLWMNCVVQSTGQMQCKMYDSMLALPQDLQAARALMVISIIVGALGMLLSVVGGKCTNCME-DETVKAKIMITAGAVFIVASMLIMVPVSWTAHNVIRDFYNPMVASGQKREMGASLYVGWAASGLLLLGGGLLCCSCPPRSNDKPYSAKYSAARSVPASNYV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14493-1", "uniprot_id": "CLD4_HUMAN", "id": "O14493-1", "name": "Claudin-4", "aln": "MASMGLQVMGIALAVLGWLAVMLCCALPMWRVTAFIGSNIVTSQTIWEGLWMNCVVQSTGQMQCKVYDSLLALPQDLQAARALVIISIIVAALGVLLSVVGGKCTNCLE-DESAKAKTMIVAGVVFLLAGLMVIVPVSWTAHNIIQDFYNPLVASGQKREMGASLYVGWAASGLLLLGGGLLCCNCPPR-TDKPYSAKYSAARSAAASNYV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9YH91-1", "uniprot_id": "CLDY_DANRE", "id": "Q9YH91-1", "name": "Claudin-like protein ZF-A89", "aln": "MASVGLQLLATVLAIIGWLGEIVICALPMWKVTAFIGNNIVTAQIFWEGLWMNCVQQSTGQMQCKVYDSMLALPQDLQAARALVVISIIVTFMGVFLTIAGGKCTNCIE-DQDAKAKVVVAAGVFFLVGGILCLIPVCWSANSVIKDFYNPTLSDAQKRELGASLFIGWCASGLLLLGGALLCCQCPKN-EGRAYSVKYSAPRSAPGA-YV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1P6R7-1", "uniprot_id": "A0A8M1P6R7_DANRE", "id": "A0A8M1P6R7-1", "name": "", "aln": "MVSAGLQMVGIALAVIGWIGVIVVCILPMWQVTAFIGQNIVTAQVTWEGIWMSCVVQSTGQMQCKVYDSMLALSSDLQAARALCIISILVGVVGILLAAAGGKCTTCIK-EERAKAKVCVISGAIFIVAGVLCLIPVCWTANNIIRDFYNPMTNSAQKRELGASLFIGWGASALLIIGGSLLCANCPPQ-D--QYKATYTARSGGTKG-YV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9YH90-1", "uniprot_id": "CLDZ_DANRE", "id": "Q9YH90-1", "name": "Claudin-like protein ZF-A9", "aln": "-MSTGLQLLGTTLGTLGWLGIIISCAIPLWRVTAFIGNNIVTAQTMWEGLWMSCVVQSTGQMQCKVYDSMLALAQDLQASRAILVISAIVGLIAMFASFAGGKCTNCLA-DNSAKALVATTGGVAFIIAGILGLVPPSWTANTIIRDFYNPLVAEAQKREFGAAIFICWGAAVLLVIGGGLLCSSYPKGRTSSRGRYTPASQNGRERSEYV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M2B8H5-1", "uniprot_id": "A0A8M2B8H5_DANRE", "id": "A0A8M2B8H5-1", "name": "Claudin", "aln": "MRTR--QFVAAFLALVGLCGTILICALPMWKVSAFVGANIVTAQVYWQGLWMNCVLQSTGHMQCMAYYSVLALTQDLQAARGLICASIGVSAIAFGMMVVGANCTRFYREDQLKKTNIGISAGALYIVGGVMCLVAVCWQTSIIVMNFYNPQVIAGTQGELGACIYIGWVAGFLLIIGGGLLLS-------------TYSNRCC-------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *.:. *. :* . :: * :*:*:*:**:* ****:* *:*:**.** ****:*** * *:***..****:*.: * * :.. .*.:** :: *: .*. :::..:: ::. .* : :: :**** . : *:**.::: * *. **::**.** . . : ", "identical_positions": 61, "similar_positions": 65, "identity": "28.91%" }, { "cls_id": "homologset.agr.MGI:1314633", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O55070-1", "uniprot_id": "DNSL3_MOUSE", "id": "O55070-1", "name": "Deoxyribonuclease gamma", "aln": "MSLHPASPRLASLLLFILALHDTLALRLCSFNVRSFGASKKENHEAMDIIVKIIKRCDLILLMEIKDSSNNICPMLMEKLNGNSRRSTTYNYVISSRLGRNTYKEQYAFVYKEKLVSVKTKYHYHDYQDGDTDVFSREPFVVWFHSPFTAVKDFVIVPLHTTPETSVKEIDELVDVYTDVRSQWKTENFIFMGDFNAGCSYVPKKAWQNIRLRTDPKFVWLIGDQEDTTVKKSTSCAYDRIVLCGQEIVNSVVPRSSGVFDFQKAYDLSEEEALDVSDHFPVEFKLQSSRAFTNNRKSVSLKKRKKGNRS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O89107-1", "uniprot_id": "DNSL3_RAT", "id": "O89107-1", "name": "Deoxyribonuclease gamma", "aln": "MSLYPASPYLASLLLFILALHGALSLRLCSFNVRSFGESKKENHNAMDIIVKIIKRCDLILLMEIKDSNNNICPMLMEKLNGNSRRSTTYNYVISSRLGRNTYKEQYAFLYKEKLVSVKAKYLYHDYQDGDTDVFSREPFVVWFQAPFTAAKDFVIVPLHTTPETSVKEIDELADVYTDVRRRWKAENFIFMGDFNAGCSYVPKKAWKNIRLRTDPNFVWLIGDQEDTTVKKSTSCAYDRIVLRGQEIVNSVVPRSSGVFDFQKAYELSEEEALDVSDHFPVEFKLQSSRAFTNSRKSVSLKKKKKGSRS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q13609-1", "uniprot_id": "DNSL3_HUMAN", "id": "Q13609-1", "name": "Deoxyribonuclease gamma", "aln": "-----MSRELAPLLLLLLSIHSALAMRICSFNVRSFGESKQEDKNAMDVIVKVIKRCDIILVMEIKDSNNRICPILMEKLNRNSRRGITYNYVISSRLGRNTYKEQYAFLYKEKLVSVKRSYHYHDYQDGDADVFSREPFVVWFQSPHTAVKDFVIIPLHTTPETSVKEIDELVEVYTDVKHRWKAENFIFMGDFNAGCSYVPKKAWKNIRLRTDPRFVWLIGDQEDTTVKKSTNCAYDRIVLRGQEIVSSVVPKSNSVFDFQKAYKLTEEEALDVSDHFPVEFKLQSSRAFTNSKKSVTLRKKTKSKRS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * **.***::*::*.:*::*:********* **:*:::***:***:*****:**:******.*.***:****** ****. *********************:********* .* ********:************::*.**.*****:****************.:*****: :**:*********************:********.*****************.******** *****.****:*..********.*:*************************.:***:*:*:.*..**", "identical_positions": 243, "similar_positions": 52, "identity": "78.39%" }, { "cls_id": "homologset.agr.MGI:1314635", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z1S3-1", "uniprot_id": "GRP1_MOUSE", "id": "Q9Z1S3-1", "name": "RAS guanyl-releasing protein 1", "aln": "MGTLGKAREAPRKPC------HGSRAGPKARLEAKSTNSPLPAQPS-LAQITQFRMMVSLGHLAKGASLDDLIDS----CIQSFDADGNLCRNNQLLQVMLTMHRIIISSAEL--------------LQKVMNLYKDALEKNSPGVCLKICYFVRYWITEFWIMFK-----------MDASLTSTMEEFQDLVKANGEETHCHLIDTTQINSRDWSR-------------KLTQRIKSNTSKKRK------------------------------------------------------------VSLLFDHLEPEELSEHLTYLEFKSFRRISFSDYQNYLVNSCVKE-----------NPTMERSIALCNGISQWVQLMVLSRPTPQLRAEVFIKFIHVAQKLHQLQNFNTLMAVIGGLCHSS--------------------------------------------------------------------------------------------ISRLKETSSHVPHEINKVLGEMTELLSSCRNYDNYRR--AYGECTHFKIPILGVHLKDLISLYEAMPDYLEDGKVNVQKLLALYNHINELVQLQEMAPPLDANKDLVHLLTLS--------------LDLYYTEDEIYELSYAREPRNHRAPPLTPSKPPVVVDWASGVSPKPDPKTIS----------------KHVQRMVDSVFKNYDLDQD------------------------------------------------GYISQEEFEKIAASFPFSFCVMDKDR-------EGLISRDEITAYFMRASSIYSKLG---------------------------LGFP--HNFQETTYLKPTFCDNCAGFLWGV-------------------------------IKQGYRCKDCGMNCHKQCKDLVVFECKKRIKSPAISTEN-----------ISSVVPMSTLCPLGTKDLLHAPEEGS------FIFQNGEIVDHSEESKDR-----------------------------------TIMLLGVSSQKISVRLKRTVAHKSTQTES----------------------------------------FPWVGGETTPGHFVLSSPR-----------------------------------KSAQGALYVH-SPASPCPSPALVRKRAF----------------------------------------------VKWENKESLIKPKPEL-HLRLRTYQELEQEINTLKADNDALKIQLKY----AQKKIESLQLGKSNHVLAQMDHGDSA------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9R1K8-1", "uniprot_id": "GRP1_RAT", "id": "Q9R1K8-1", "name": "RAS guanyl-releasing protein 1", "aln": "MGTLGKAREAPRKPC------HGSRAGPKGRLEAKSTNSPLPAQPS-LAQITQFRMMVSLGHLAKGASLDDLIDS----CIQSFDADGNLCRSNQLLQVMLTMHRIIISSAEL--------------LQKLMNLYKDALEKNSPGICLKICYFVRYWITEFWIMFK-----------MDASLTSTMEEFQDLVKANGEESHCHLIDTTQINSRDWSR-------------KLTQRIKSNTSKKRK------------------------------------------------------------VSLLFDHLEPEELSEHLTYLEFKSFRRISFSDYQNYLVNSCVKE-----------NPTMERSIALCNGISQWVQLMVLSRPTPQLRAEVFIKFIHVAQKLHQLQNFNTLMAVIGGLCHSS--------------------------------------------------------------------------------------------ISRLKETSSHVPHEINKVLGEMTELLSSCRNYDNYRR--AYGECTHFKIPILGVHLKDLISLYEAMPDYLEDGKVNVQKLLALYNHINELVQLQDVAPPLDANKDLVHLLTLS--------------LDLYYTEDEIYELSYAREPRNHRAPPLTPSKPPVVVDWASGVSPKPDPKTIS----------------KHVQRMVDSVFKNYDLDQD------------------------------------------------GYISQEEFEKIAASFPFSFCVMDKDR-------EGLISRDEITAYFMRASSIYSKLG---------------------------LGFP--HNFQETTYLKPTFCDNCAGFLWGV-------------------------------IKQGYRCKDCGMNCHKQCKDLVVFECKKRSKSPAVSTEN-----------ISSVVPMSTLCPLGTKDLLHAPEEGS------FIFQNGEVVDHSEESKDR-----------------------------------TIMLLGVSSQKISVRLKRTVAHKTTQTES----------------------------------------FPWVGGEMPPGHFVLTSPR-----------------------------------KSAQGALYVH-SPASPCPSPALVRKRAF----------------------------------------------VKWENKESLIKPKPEL-HLRLRTYQELEQEVNTLRADNDALKIQLKY----AQKQIESLQLGKSNHVLAQMDHGDGT------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O95267-1", "uniprot_id": "GRP1_HUMAN", "id": "O95267-1", "name": "RAS guanyl-releasing protein 1", "aln": "MGTLGKAREAPRKPS------HGCRAASKARLEAKPANSPFPSHPS-LAHITQFRMMVSLGHLAKGASLDDLIDS----CIQSFDADGNLCRSNQLLQVMLTMHRIVISSAEL--------------LQKVITLYKDALAKNSPGLCLKICYFVRYWITEFWVMFK-----------MDASLTDTMEEFQELVKAKGEELHCRLIDTTQINARDWSR-------------KLTQRIKSNTSKKRK------------------------------------------------------------VSLLFDHLEPEELSEHLTYLEFKSFRRISFSDYQNYLVNSCVKE-----------NPTMERSIALCNGISQWVQLMVLSRPTPQLRAEVFIKFIQVAQKLHQLQNFNTLMAVIGGLCHSS--------------------------------------------------------------------------------------------ISRLKETSSHVPHEINKVLGEMTELLSSSRNYDNYRR--AYGECTDFKIPILGVHLKDLISLYEAMPDYLEDGKVNVHKLLALYNHISELVQLQEVAPPLEANKDLVHLLTLS--------------LDLYYTEDEIYELSYAREPRNHRAPPLTPSKPPVVVDWASGVSPKPDPKTIS----------------KHVQRMVDSVFKNYDHDQD------------------------------------------------GYISQEEFEKIAASFPFSFCVMDKDR-------EGLISRDEITAYFMRASSIYSKLG---------------------------LGFP--HNFQETTYLKPTFCDNCAGFLWGV-------------------------------IKQGYRCKDCGMNCHKQCKDLVVFECKKRAKNPVAPTEN-----------NTSVGPVSNLCSLGAKDLLHAPEEGP------FTFPNGEAVEHGEESKDR-----------------------------------TIMLMGVSSQKISLRLKRAVAHKATQTES----------------------------------------QPWIGSEGPSGPFVLSSPR-----------------------------------KTAQDTLYVLPSPTSPCPSPVLVRKRAF----------------------------------------------VKWENKDSLIKSKEELRHLRLPTYQELEQEINTLKADNDALKIQLKY----AQKKIESLQLEKSNHVLAQMEQGDCS------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P07866-1", "uniprot_id": "LTE1_YEAST", "id": "P07866-1", "name": "Guanine nucleotide exchange factor LTE1", "aln": "MEIFSQKDYYPTPSSNVISYESDCVSKPVNSADLPALIVHLSSPLEGVDYNASADFFLIYRNFITPQDLHDLLIYRFRWCIREITTNAAKAKRRRIGEVALVRTFVLLRHSILNYFVQDFLPNITLRLRLIEFLNDKHIEQYPKIISSCIINLKKNWVHCSKLVWENIELNEPDKLDFDAWLHYSLKDFTQLESLHKRGSRLSIYARQSFASPDFRNQSVLSLYKTSDVFRLPEKLQSSNSSKNQRSPSMLLFPDNTSNVYSKHRIAKEPSVDNESEDMSDSKQKISHLSKVTLVSTLMKGVDYPSSYAVDKIMPPTPAKKVEFILNSLYIPEDLNEQSGTLQGTSTTSSLDNNSNSNSRSNTSSMSVLHRSAIGLLAKWMKNHNRHDSSNDKKFMSAIKPANQKPEMDAFVKYVVSISSLNRKSSKEEEEEFLNSDSSKFDILSARTIDEVESLLHLQNQLIEKVQTHSNNNRGPTVNVDCERREHIHDIKILQQNSFKPSNDNFSAMDNLDLYQTVSSIAQSVISLTNTLNKQLQNNESNMQPSPSYDALQRRKVKSLTTAYYNKMHGSYSAESMRLFDKDNSSSRTDENGPQRLLFHETDKTNSEAITNMTPRRKNHSQSQKSMTSSPLKNVLPDLKESSPLNDSREDTESITYSYDSELSSSSPPRDTVTKKSRKVRNIVNNTDSPTLKTKTGFLNLREFTFEDTKSLDEKKSTIDGLEKNYDNKENQESEYESTKKLDNSLDASSEANNYDITTRKKHSSCNHKIKQAVVRPASGRISISRVQSIAITPTKELSIVDPEQNKSNSVIEEISEIEPLNLEYNKKSALYSDTSSTVISISTSKLFESAQNSPLKQTQNPQREFPNGTSVSETNRIRLSIAPTIESVVSDLNSITTGSTVETFETSRDLPVPHQRIINLREEYQRGNQDIISNTSSLHELKTIDLSDSNNDLESPSTHAKNNKYFFSPDDGSIDVASPMKNVEELKSKFLKNESETNSNISGSVLTMDDIDINDTSSARNTRRANSESAFTGSLNKKNLNEIANMLDDSINDDPITVALMKLEGTYEKIPEKPENTKSSDAIGIKTSKLADEVEMLNLNNLPSFQNSPAEKRKSLLIERRRQTIMNIPFTPDQSEKEGFTSSSPEKIDVSANVDVAVQAAQIQELIGQYRIHDSRLMISNNESHVPFILMYDSLSVAQQMTLIEKEILGEIDWKDLLDLKMKHEGPQVISWLQLLVRNETLSGIDLAISRFNLTVDWIISEILLTKSSKMKRNVIQRFIHVADHCRTFQNFNTLMEIILALSSSVVQKFTDAWRLIEPGDLLTWEELKKIPSLDRNYSTIRNLLNSVNPLVGCVPFIVVYLSDLSANAEKKDWILEDKVVNYNKFDTNVQIVKNFIQRVQWSKFYTFKVNHELLSKCVYISTLTQEEINELST", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :.: * .. .. : . : . :.: . : :. ::: :: . .*.**: **:.: ::. .: .:: :* *. ::: : * *: : * .. : : . :. * : : *: :::: :** * ::::* :* . : . : : .: : *: . :*.::::*..*.*.: * .*:: * :::: :: . : .:.: .. * .:.... . * . *: ..*. .: * . . . : *:. *: *:: ::: * . :. *..* :.* :* : :: :.: :** * : . :... .** :* . . * : : * : : : *:: . . .: . ::** .. .: : :::* . :.: : :* * *: : * ** * . .* * :* . * . : .* ** : .. : :*.: **** .:: * ** ...:.** : . .:.::* :: * : . : :. : : *::**. . ** ...**. :: ::. . ..: .: ::* : .. .. :: * : : :.:: :.* ::* . *:..: * :* * : .* .. : : : : : .. : * ::* : : :**. : :.: : .: :: *: .: *. :**. : :: .: : .. * . . .*:.*. : *.* .: *:. . :: : : : .: :. .*:: * ::* * .** :: :* :...:*: : . . ", "identical_positions": 116, "similar_positions": 348, "identity": "8.08%" }, { "cls_id": "homologset.agr.MGI:1314647", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O54794-1", "uniprot_id": "AQP7_MOUSE", "id": "O54794-1", "name": "Aquaporin-7", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAPRSVLETIQSVL-----------------------------------QKNMVREFLAEFLST--------YVMMVFGLGSVAHM------------------------------------VLGE-NSGSYLGVNLGFGFGVTMGVHVAG--GISGAHMNAAVTFTNCALGRMTWKKFPVYVLGQFLGSFSAAATTYLIFYGAINHFAGGDLLVTGSKATANIFATYLPEYMTLWRGFLDEAFVTGMLQLCLFAITDKKNSPALQGTEPLVIGILVTVLGVSLGMNSGYAINPSRDLPPRLFTFIAGWGKQVFRAGNNWW-WVPVVAPLLGAYLGGIVYLGLIHPSIPQDP-------------------------------------------QRLENFTARDQKVTASYKNAASAN------------------------ISGSVPLEHF-----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P56403-1", "uniprot_id": "AQP7_RAT", "id": "P56403-1", "name": "Aquaporin-7", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAG-SVLENIQSVL-----------------------------------QKTWVREFLAEFLST--------YVLMVFGLGSVAHM------------------------------------VLGE-RLGSYLGVNLGFGFGVTMGIHVAG--GISGAHMNAAVTFTNCALGRMAWKKFPIYVLGQFLGSFLAAATTYLIFYGAINHYAGGELLVTGPKSTANIFATYLPEHMTLWRGFVDEVFVTGMLQLCIFAITDKLNSPALQGTEPLMIGILVCVLGVSLGMNTGYAINPSRDLPPRFFTFIAGWGKKVFSAGNNWW-WVPVVAPLLGAYLGGIVYLGLIHAGIP--P-------------------------------------------Q-------------------------------------------------GS-----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O14520-1", "uniprot_id": "AQP7_HUMAN", "id": "O14520-1", "name": "Aquaporin-7", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVQASGHRRSTRGSKMVSWSVIAKIQEIL-----------------------------------QRKMVREFLAEFMST--------YVMMVFGLGSVAHM------------------------------------VLNK-KYGSYLGVNLGFGFGVTMGVHVAG--RISGAHMNAAVTFANCALGRVPWRKFPVYVLGQFLGSFLAAATIYSLFYTAILHFSGGQLMVTGPVATAGIFATYLPDHMTLWRGFLNEAWLTGMLQLCLFAITDQENNPALPGTEALVIGILVVIIGVSLGMNTGYAINPSRDLPPRIFTFIAGWGKQVFSNGENWW-WVPVVAPLLGAYLGGIIYLVFIGSTIPREP-------------------------------------------LKLEDSVAYEDHGITVLPKMGSHEPTISPLTPVSVSPANRSSVHPAPPLHESMALEHF-----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A075B734-1", "uniprot_id": "AQP7B_HUMAN", "id": "A0A075B734-1", "name": "Putative aquaporin-7B", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVQASGHRRSTRGSKMVSWSVIAKIQEIWCEED-------------------------------ERKMVREFLAEFMST--------YVMMVFGLGSVAHM------------------------------------VLNK-TYGSYLGVNLGFGFGVTMGVHVAG--RISGAHMNAAVTFTNCALGRVPWRKFPVHVLGQFLGSFLAAATIYSLFYTAILHFSGGELMVTGPFATAGIFATYLPDHMTLWRGFLNEEWLTRMLQLCLFTITDQENNPALPGTHALVISILVVIIRVSHGINTGYAINPSRDPPPSIFTFIAGWGKQVFSDGENWW-WVPVVAPLLGASLGGIIYLVFIGSTIPREP-------------------------------------------LKLEDSVAYEDHGITVLPKMGSHEPMISPLTLISVSLANRSSVHSAPPLHESMALEHF-----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58I859-1", "uniprot_id": "A0AC58I859_DANRE", "id": "A0AC58I859-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNRQLIQHVALPAATHLRETHTHTHTHTHTTDNLAYPIYLHFGLWGKPDYPEHP----------IGVCNGCHRTTAQVCSLHNSYWWSGETVMEPIWWMEVFGLGTVAQV------------------------------------VTGEGYFGEYLSINIGFGLAVAMGVHVGG--KVSGAHMNAAVSFTMCVFGRLRWKMLPLYVFAQFLGSFLAAGTIFSLYYDAINHFCGGNLTVSGPKATAGIFATYPAPYISVYTGFFDQVAGTGLLLLCLMALSDQRNQPLVSGGEAVGVGLLVMLIGVSMGSNSGYAINPTRDLGPRLFTLMAGWGTEVFRAGNCWW-WVPLVAPFIGGVLGALIYKALVELHHP-----------------------------------------------DLKSTITRPAVDPECIPLDKCKN--------------------------GRIEIPV------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P43549-1", "uniprot_id": "AQY3_YEAST", "id": "P43549-1", "name": "Aquaglycerol porin AQY3", "aln": "MSYESGRSSSSSESTRPPTLKEEPNGKIAWEESVKKSRENNENDSTLLRRKLGETRKAIETGGSSRNKLSALTPLKKVVDERKDSVQPQVPSMGFTYSLPNLKTLNSFSDAEQARIMQDYLSRGVNQGNSNNYVDPLYRQLNPTMGSSRNRPVWSLNQPLPHVLDRGLAAKMIQKNMDARSRASSRRGSTDISRGGSTTSVKDWKRLLRGAAPGKKLGDIEAQTQRDNTVGADVKPTKLEPENPQKPSNTHIENVSRKKKRTSHNVNFSLGDESYASSIADAESRKLKNMQTLDGSTPVYTKLPEELIEEENKSTSALDGNEIGASEDEDADIMTFPNFWAKIRYHMREPFAEFLGT--------LVLVIFGVGGNLQA------------------------------------TVTKGSGGSYESLSFAWGFGCMLGVYVAG--GISGGHINPAVTISMAIFRKFPWKKVPVYIVAQIIGAYFGGAMAYGYFWSSITEFEGGPHIRT--TATGACLFTDPKSYVTWRNAFFDEFIGASILVGCLMALLDDSNAPPGNGMTALIIGFLVAAIGMALGYQTSFTINPARDLGPRIFASMIGYGPHAFHLTHWWWTWGAWGGPIAGGIAGALIYDIFIFTGCESPV-------------------------------------------NYPDNGYIENRVGKLLHAEFHQNDGTVS----------DESGVNSNSNTGSKKSVPTSS----------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P23900-1", "uniprot_id": "FPS1_YEAST", "id": "P23900-1", "name": "Glycerol uptake/efflux facilitator protein", "aln": "-----------------------------------------------MSNPQKALNDFLSSESVHTHDSSRKQSNKQSSDEGRSSSQPSHHHSGGTNNNNNNNNNNNNSNNNNN----------GNDGGNDDDYDYEMQDYRPSPQSARPTPTYVPQYSVESGTAFPIQEVIPSAYINTQDINHKDNGPPSASSNRAFR-----------PRGQTTVSANVLNIEDFYKNADDAHTIPESHLSRRRSRSRATSNAGHSANTGATNGRTTGAQTNMESNESPRNVPIMVKPKTLYQNPQTPTVLPSTYHPIN--------------------------KWSSVKNTYLKEFLAEFMGT--------MVMIIFGSAVVCQVNVAGKIQQDNFNVALDNLNVTGSSAETIDAMKSLTSLVSSVAGGTFDDVALGWAAAVVMGYFCAGGSAISGAHLNPSITLANLVYRGFPLKKVPYYFAGQLIGAFTGALILFIWYKRVLQEAYSDWWMNES---VAGMFCVFPKPYLSSGRQFFSEFLCGAMLQAGTFALTDPYTCLS-SDVFPLMMFILIFIINASMAYQTGTAMNLARDLGPRLALYAVGFDHKMLWVHHHHFFWVPMVGPFIGALMGGLVYDVCIYQGHESPVNWSLPVYKEMIMRAWFRRPGWKKRNRARRTSDLSDFSYNNDDDEEFGERMALQKTKTKSSISDNENEAGEKKVQFKSVQRGKRTFGGIPTILEEEDSIETASLGATTTDSIGLSDTSSEDSHYGNAKKVT", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : . .: : : :** . : . * : .: :.:. . :* . .* :**.*:*.::::: . : .* :. .*::*:: .. : : : . .. .. : . ::: *..: :* ::: * . . .: : :*: : : . ::. ::* :** * : *:. . : . : * . .*: *. *.::* : ", "identical_positions": 26, "similar_positions": 95, "identity": "3.35%" }, { "cls_id": "homologset.agr.MGI:1314653", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35889-1", "uniprot_id": "AFAD_RAT", "id": "O35889-1", "name": "Afadin", "aln": "MSAGGRDEERRKLADIIHHWNANRLDLFEISQPTEDLEFHGVMRFYFQDKAAGNFATKCIRVSSTATTQDVIETLAEKFRPDMRMLSSPKYSLYEVHVSGE-RRLDIDEKPLVVQLNWNKDDREGRFVLKNENDAIP----------AKKAQSNGPEKQEKEGVIQNFKRTLSKKEKKEKKKREKEALRQASDKEERPSQGDDSENSRLAAEVYKDMPETSFTRTISNPEVVMKRRRQQKLEKRMQEFRSSDGRPDSGGTLRIYADSLKPNIPYKTILLSTTDPADFAVAESLEKYGLEKENPKDYCIARVMLPPGAQHSDERGAKEIILDDDECPLQIFREWPSDKGILVFQLKRRPPDYIPKKMKKHVEGKPLKGKDRADGSGYGSALPPEKLPYLVELSPGRRNHFAYYSYHTYEDGSDSRDKPKLYRLQLSVTEVGTEKFDDNSIQLFGPGIQPHHCDLTNMDGVVTVTPRSMDAETYVDGQRISETTMLQSGMRLQFGTSHVFKFVDPIQD----HVLSKRSVDGGLMVKG-PRHKPGAVQETTFELGGDIHSGTALPASRSTTRLDSDRVSSASSTAERGMVKPMIRLDQEQDYRRRE----------------------------------------------SRTQDAAGPELMLPASIEFRESSEDSFLSAIINYTNSSTVHFKLSPTYVLYMACRYVLSSQHRPDISPTERTHKAIAVVNKMVSMMEGVIQEVDQVDQKQKNIAGALAFWMANASELLNFIKQDRDLSRITLDAQDVLAHLVQMAFKYLVHCLQSELNNYMPAFLDDPEENSLQRPKIDDVLHTLTGAMSLLRRCRVNAALTIQLFSQLFHFINMWLFNRLVTDPDSGLCSHYWGAIIRQQLGHIEAWAEKQGLELAADCHLSRIVQATTLLTMDKYVPDDIPNINSTCFKLNSLQLQALLQNYHCAPDEPFIPTDLIENVVAVAENTADELARSDGRDVQLEEDPDLQLPFLLPEDGYSCDVVRNIPNGLQEFLDPLCQRGFCRLVPHTRSPGTWTIYFEGADYESHLMRENTELTQPLRKEPEVITVTLKKQNGMGLSIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGLSQERAAELMTRTSSVVTLEVAKQGAIYHGLATLLNQPSPMMQRISDRRG-------SGKPRPKSEGFELYNNSAQNGSPESPQMPWTEYSEP-------------------------KKLPGDDRLMKNRADHRSSPNVANQPPSPGGKSPYTSG------TAAKITSVSTGN------------LCTEEQTPPPRPEAYPIPTQTYTREYFTFPASKSQDRMAPVQNQWPNYEEKPHMHTESDHASIAIQRVTRSQEELREEKVYQLERHRVESGMDRKCDSDMWINQSSSVESSTSSQEHLNHSSKSVTPASTLTKSGPGRWKTPAAVLPTPVAVSQPIRTDLPPPPPPPPAHYTSDFDGISMDLPLPPPP-ANQAAPQSAQVAAAERKKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPASFSPL-ATQAKPEKPSTLQRPQE----TVIRELQPQQQPRTIERRDLQYITISKEELSSGDSLS-----------PDPWKRDAREKLEKQQQMHIVDMLSKEIHELQNKGDRTAEESDRLRKLMLEWQFQKRLQESKQKDEDDDEEEDDDVDTMLIMQRLEAERRARLQD---EERRRQQQLEEMRKREVEDRVRQEEDGRHQEEERVKRDAEEKRRQEEGYYSR----------LEAERRRQHEEAARRLLEPEEPG------LSRPPLPQDYEPPSQSSAPSAPPPPPQRNASYLKT-------------------------------------------------------------------------------------QVLSPDSLFTAKFVAYDDDDEEENYVPAGP----------------------------------------------------NSYSGSAGTTAGTYDAPRDTREK---LSRSQDADLPGSSGAPENLTFRERQRLFSQGQDVSDKVKASRKLTELENELNTK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QZQ1-3", "uniprot_id": "AFAD_MOUSE", "id": "Q9QZQ1-3", "name": "Afadin", "aln": "MSAGGRDEERRKLADIIHHWNANRLDLFEISQPTEDLEFHGVMRFYFQDKAAGNFATKCIRVSSTATTQDVIETLAEKFRPDMRMLSSPKYSLYEVHVSGE-RRLDIDEKPLVVQLNWNKDDREGRFVLKNENDAIP----------AKKAQSNGPEKQEKEGVIQNFKRTLSKKEKKEKKKKEKEALRQASDKEERPSQGDDSENSRLAAEVYKDMPETSFTRTISNPEVVMKRRRQQKLEKRMQEFRSSDGRPDSGGTLRIYADSLKPNIPYKTILLSTTDTADFAVAESLEKYGLEKENPKDYCIARVMLPPGAQHSDERGAKEIILDDDECPLQIFREWPSDKGILVFQLKRRPPDYIPKKMKKHVEGKSLKGKDRADGSGYGSALPPEKLPYLVELSPGRRNHFAYYSYHTYEDGSDSRDKPKLYRLQLSVTEVGTEKFDDNSIQLFGPGIQPHHCDLTNMDGVVTVTPRSMDAETYVDGQRISETTMLQSGMRLQFGTSHVFKFVDPIQD----HVLSKRSVDGGLMVKG-PRHKPGAVQETTFELGGDVHSGTALPASRSTTRLDSDRVSSASSTAERGMVKPMIRLDQEQEYRRRE----------------------------------------------NRTQDATGPELILPASIEFRESSEDSFLSAIINYTNSSTVHFKLSPTYVLYMACRYVLSSQHRPDISPTERTHKAIAVVNKMVSMMEGVIQ-------KQKNIAGALAFWMANASELLNFIKQDRDLSRITLDAQDVLAHLVQMAFKYLVHCLQSELNNYMPAFLDDPEENSLQRPKIDDVLHTLTGAMSLLRRCRVNAALTIQLFSQLFHFINMWLFNRLVTDPDSGLCSHYWGAIIRQQLGHIEAWAEKQGLELAADCHLSRIVQATTLLTMDKYVPDDIPNINSTCFKLNSLQLQALLQNYHCAPDEPFIPTDLIENVVAVAENTADELARSDGRDVQLEEDPDLQLPFLLPEDGYSCDVVRNIPNGLQEFLDPLCQRGFCRLVPHTRSPGTWTIYFEGADYESHLMRENAELAQPLRKEPEIITVTLKKQNGMGLSIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGLSQERAAELMTRTSSVVTLEVAKQGAIYHGLATLLNQPSPMMQRISDRRG-------SGKPRPKSEGFELYNNSAQNGSPESPQMPWTEYSEP-------------------------KKLPGDDRLMKNRADHRSSPNVANQPPSPGGKGPYTSG------TAAKITSVSTGN------------LCTEEQSPPPRPEAYPIPTQTYTREYFTFPASKSQDRMAPPQSQWPNYEEKPHVHTESNHSSIAIQRVTRSQEELREEKVYQLERHRVEAGMDRKCDSDMWINQSSSVESSTSSQEHLNHSSKSVTPASTLTKSGPGRWKTPAAVLPTPVAVSQPIRTDLPPPPPPPPVHYTSEFDGIPMDLPLPPPP-ANQAGPQSAQVAAAEWKKREEHQRWYEKEKARLEEERERKRREQERKLGQMRSQTLNPASFSPL-ATQAKPEKPSTLQRPQE----TVIRELQPQQQPRTIERKDLQYITISKEELSSGDSLS-----------PDPWKRDAREKLEKQQQMHIVDMLSKEIHELQNKVDRTAEESDRLRKLMLEWQFQKRLQESKQKDEDDDEEEDDDVDTMLIMQRLEAERRARMQD---EERRRQQQLEEMRKREAEDRVRQEEDGRHQEEERVKRDAEEKRRQEEGYYSR----------LEAERRRQHEEAARRLLEPEEPG------LSRPPLPRDYEPPSLSSAPCAPPPPPQRNASYLKT-------------------------------------------------------------------------------------QVLSPDSLFTAKFVAYDE--EEEDYGPAGP----------------------------------------------------NSYSGSAGTAVGAYDAPREAREK---LTRSQDADLPGSSGAPENLTFKERQRLFSQGQDVSDKVKASRKLTELENELNTK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P55196-4", "uniprot_id": "AFAD_HUMAN", "id": "P55196-4", "name": "Afadin", "aln": "MSAGGRDEERRKLADIIHHWNANRLDLFEISQPTEDLEFHGVMRFYFQDKAAGNFATKCIRVSSTATTQDVIETLAEKFRPDMRMLSSPKYSLYEVHVSGE-RRLDIDEKPLVVQLNWNKDDREGRFVLKNENDAIP----------PKKAQSNGPEKQEKEGVIQNFKRTLSKKEKKEKKKREKEALRQASDKDDRPFQGEDVENSRLAAEVYKDMPETSFTRTISNPEVVMKRRRQQKLEKRMQEFRSSDGRPDSGGTLRIYADSLKPNIPYKTILLSTTDPADFAVAEALEKYGLEKENPKDYCIARVMLPPGAQHSDEKGAKEIILDDDECPLQIFREWPSDKGILVFQLKRRPPDHIPKKTKKHLEGKTPKGKERADGSGYGSTLPPEKLPYLVELSPGRRNHFAYYNYHTYEDGSDSRDKPKLYRLQLSVTEVGTEKLDDNSIQLFGPGIQPHHCDLTNMDGVVTVTPRSMDAETYVEGQRISETTMLQSGMKVQFGASHVFKFVDPSQD----HALAKRSVDGGLMVKG-PRHKPGIVQETTFDLGGDIHSGTALPTSKSTTRLDSDRVSSASSTAERGMVKPMIRVEQQPDYRRQE----------------------------------------------SRTQDASGPELILPASIEFRESSEDSFLSAIINYTNSSTVHFKLSPTYVLYMACRYVLSNQYRPDISPTERTHKVIAVVNKMVSMMEGVIQ-------KQKNIAGALAFWMANASELLNFIKQDRDLSRITLDAQDVLAHLVQMAFKYLVHCLQSELNNYMPAFLDDPEENSLQRPKIDDVLHTLTGAMSLLRRCRVNAALTIQLFSQLFHFINMWLFNRLVTDPDSGLCSHYWGAIIRQQLGHIEAWAEKQGLELAADCHLSRIVQATTLLTMDKYAPDDIPNINSTCFKLNSLQLQALLQNYHCAPDEPFIPTDLIENVVTVAENTADELARSDGREVQLEEDPDLQLPFLLPEDGYSCDVVRNIPNGLQEFLDPLCQRGFCRLIPHTRSPGTWTIYFEGADYESHLLRENTELAQPLRKEPEIITVTLKKQNGMGLSIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGLSQERAAELMTRTSSVVTLEVAKQGAIYHGLATLLNQPSPMMQRISDRRG-------SGKPRPKSEGFELYNNSTQNGSPESPQLPWAEYSEP-------------------------KKLPGDDRLMKNRADHRSSPNVANQPPSPGGKSAYASG------TTAKITSVSTGN------------LCTEEQTPPPRPEAYPIPTQTYTREYFTFPASKSQDRMAPPQNQWPNYEEKPHMHTDSNHSSIAIQRVTRSQEELREDKAYQLERHRIEAAMDRKSDSDMWINQSSSLDSSTSSQEHLNHSSKSVTPASTLTKSGPGRWKTPAAIPATPVAVSQPIRTDLPPPPPPPPVHYAGDFDGMSMDLPLPPPPSANQIGLPSAQVAAAERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKPSTLQRPQE----TVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLS-----------PDPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEEEEDDDVDTMLIMQRLEAERRARLQD---EERRRQQQLEEMRKREAEDRARQEEERRRQEEERTKRDAEEKRRQEEGYYSR----------LEAERRRQHDEAARRLLEPEAPG------LCRPPLPRDYEPPSPSPAPGAPPPPPQRNASYLKT-------------------------------------------------------------------------------------QVLSPDSLFTAKFVAYNEEEEEEDCSLAGP----------------------------------------------------NSYPGSTGAAVGAHDACRDAKEK---RSKSQDADSPGSSGAPENLTFKERQRLFSQGQDVSNKVKASRKLTELENELNTK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VN82-1", "uniprot_id": "Q9VN82_DROME", "id": "Q9VN82-1", "name": "", "aln": "MSHDKKMLDREAVRSVIQQWNANRLDLFALSEPDENLLFHGVMRFYFQDAGQ-KVATKCIRVASDATVTDVIDTLIEKFRPDMRMLSVPNYALYEVHANGEERRLNADEKPLLVQLNWHIDDREGRFLLKNIDQKTTPIEQTDLNFKRKLSKREKKEQKKKEKMAKLSSDPPTSNGSHLGLGNGVGASSGSAHMNGNAGGTGGDSSDAVAGKLYTELPETSFTRSISNPEAVMRRRRQQKLEKKLQQFRSRDGGPDTGGTLKIYGESLCQDVPYKTLLLSIRDCAQAVVREMLTKYGLEKADPLHYCLVQVNS----------DGTEYILDDDECPLSILMNHPTSRGSIMFHVRRRPADSQPRRRKKKPLG-AANGANHISGDREG--------PVLVEVTHS---------------GDGGR------RIKLGSDPVEVGSANTNCLQLFGPSIQPRHCLISLLEGVCTVTPLHTDALTFVNGHHISQPTILHNGSVVMFGRVASYRFLDSPTDGRYNLALSQSQLDSACLYESRSPTSPGSWNDEDGALSSTHKSDYDHHQQANHSSAYHNNNNNSSDHPLSSTLRDVVDSKAGQDQGANSGNYDGQSLEGNLENETKSISSLKSGGSNSQDRSPKMTGSGILAGGGSGSGDTQGQEPILPAVLEFPETHQELFLRHIISELDVNVPHFKLAPVYSLYLCARYRASTHYRPELQPTERAHKLTMFLHHVANLVYSVVQ-------EQYTDPRILAFWMANSSEFLHFLKSDRHISAFSVQAQEVLAEAVQTAFRNLVNCFRLELSQTLNQFLS---ENIDHDSAAGLVLTVLGSAMALLRRCRVNAALTIQLFSQLFHYINVICFNTIVAN--SQMCTGDWGKVMTERLQLLELWAERQGLELAADCHLAKINQCAQFLQAPKSSVEEIQQLACSCFRLNSLQMAALLQ-------QEKLPRNLVDTAIRMAESVADELTRADGREVRLEESPELHLALLLPDDGFSCDVVRGIPTGLVDFLNPLQQQGMCRLAAQPTSIGLWTVYMHQFN-----ARSSSAMSNKLPQPELQLIKLHKNSNGMGLSIVAAKGAGQEKLGIYIKSVVPGGAADADGRLQAGDQLLRVDGQSLIGITQERAADYLVRTGPVVSLEVAKQGAIYHGLATLLQQPSPVIQRGNRRMSERDLTRMGGAESTKSLGPLIANNHPNHSLSLSQHLNNSHNNTLGNSNNSSIINPLAAHLPNSKSVPALHHHTGSGTISLANSKSRSTHSLHNNTSGMGGIGGAAAGGMLGQPNGSQNNANGNGNGNEQGFYQNLSVYRAQNQSQPILNERPPIAAHAAMNAYNGSSPLAPQQ--QPQQQQQSPYQQQQQQQHMQANANLPPTRPVSAYYHSQQSAQQQLQQQQQQQQQHSLQQQQFALSSGNLNGQQQQQQQHQHQHQLTLNNRTKSQQNFQHTLRMQQMMAPSMPNISNMYHHQQQQQQQLPLQQQQQQQQQPLMSSSQSMQNVNDFAGGYQNGSLEYRRSQLHDPSTLYEIQQQQLQQQQQQQQQQQQQQQASPNFIALPPKPLGSLQSPNKPNVPPSTAPKPQQDKPPLPPTATHPLFKATQQIAPGMNYVASTLDPPKGSYVASNQGNNRPLHSGSNPWEREEREKDLEMRREHIRQWREQQISELSQIVSRSPMQEEQLKTLILERDFERRAQELQEQEEQDQEQQYDKENVQELFRLAGGGQVSAIQTPITSYRQTEIKLAEMPDSNSLVDSVPPQPPAPTAQPLSSNTQQPKSILKHNRYSEGGVGPSGAPSSPSKSQKSASFADERHLHTEHPISNLAKELNQLTMLDKDNNNETLDAVVPPPPPPERNSSYLIMSQQKLRGSTGNATSSMGLLKTATSNQAAAAVEIKKASLLNTQTNNNNNLSGSLNNNTMHGSPLSAMELNAAYVSATGTGIIGGLGTPPPPPPLMQRDNKRVSFHDEENNFVSGNSQQQQLQQQYIMDNYGMEHQDLDTIREDTSYLQHNLDASMLPSMPATPDAALWNTSVQSTPGVIGAQEVYRDPRTRRLAEKQQQQQQQRAGDAVPEKLSFKEKMKMFALESGEDKTPKDKLKISRAQRDIDAVH", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** . : :*. : .:*::********* :*:* *:* *********** . :.*******:* **. ***:** *********** *:*:*****..** ***: *****:*****: *******:*** :: . * :: : *:::** : : . . :.: .: . * ::. : .. . ... :*.::*.::*******:*****.**:*********::*:*** ** **:****:**.:** ::****:*** * *: .* * * ****** :* .**:.:* ...* *********.*: : *:.:* ::*:::***.* *:: **: * . :* :: .*. * * ***:: . *...* *::*. * . . : *.:*****.***:** :: ::** **** ** *:*:*::**:.*:*:.* : ** ::*:*. * .*:: .:*.. : :. . .** :: *.. :*. . . : :. ..:*. . . :: :: . : .. . : *: * * :*** :** *: :: ** **. : .. ****:*.* **:..** *.::**::.****:** .::::..:: .*:* :* . . *******:**:*:*:*.**.:* ::::**:***. ** **: **:*:: **.: : **. ** : . . ** .* .**:*********************:**: ** :*:: * :*: ** :: ::* :* ***:***********::* *.: :* * ::* :: .:**:*****: **** : :* :*::..: :**..****:*:***:*:***.*:*:*.:***:**:******.**.** :**:** *:*:*** .:. * * **:*:. : *..: ::: * : : *:.***************:*****:**** *****.**** ****** ***:**:*::*****: :.**..**:*****************:****::** . * . .* .** * : ** .::. . * :: :. . :: .*.. : .:. **: .: *:... ** . ::* . :: .: ..** :::*: * * **.::: . * .. .*: * *.* . *::: : : . ::.:. * . : . ::. **:::: : . :.:: :.... .. ..*:* :: . ::. :. :. : : .: :*: : : * : : : *. . . : . . . : .: . ** :: :*::::::::::*::: .. . :* * .:..* : : *** :**: :* :. .::*:: : : ... * .:**:*: :** : :: ** : .::* **.. .*:. :.::*:.*:** :*::* ** ::::*:*:*:: *. :. ::: . : : :* . *: : :* ** . : : : .. : * :.. **. :: ::. . * .* *..* * * : .: . : . * .*****:**:*** .* .*: . . **:: ... *: *: . *: :. *:.: : .:.*: : .....**:*:*:*: ::*: .. ... * . *::. :.:::: ", "identical_positions": 606, "similar_positions": 625, "identity": "28.61%" }, { "cls_id": "homologset.agr.MGI:1314663", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0M6S2-1", "uniprot_id": "A0ABK0M6S2_RAT", "id": "A0ABK0M6S2-1", "name": "Y-linked testis-specific protein 1-like", "aln": "-MKPEHRTIATRRWTRSVVVYHTMSTAKKKSMSLRRMSTPSFQKRRRRRPSPQALGDIVGCRISHGWKEGDEPITQWKAIVLDQLPTNPSLYLVKYDGIECVYGLALHSDERILRLKVLPHKVVFPQVKDAHLASAMVGRVVEHKFEGKHGSKDNWRGVVLAQVPIMKDWFYITYEKDPVLYIYQLLDDYTEGNLRIIPETPPAHVKSDVDSDILTDQCVQFTRSDGSKKIGKVIYQVLAKSSVYFFKFDGKVHIYFYDLVEKNR-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "M0RB41-1", "uniprot_id": "M0RB41_RAT", "id": "M0RB41-1", "name": "", "aln": "-------------------------------MSLRRMSTQSFQKQRRRRPSPQALGNIVGCRISHGWKEGDEPVTQWKAIILDQLPTNPSLCLVKYDGIDCVYGLGLHSDERILKLKVLPHKVVFPQVKHAHLASAMVGRAVEHKFEGKHASKDNWRGVVPSQVRIMKNWFSITYEKDTVLYIYQLLDDYTEGNLRIIPETPPVEVKSDVNSDILTGQCVQFTRSDGSKKIGNFIYQVLAKPSVYFIKFYGDVHI---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0LX79-1", "uniprot_id": "A0ABK0LX79_RAT", "id": "A0ABK0LX79-1", "name": "Y-linked testis-specific protein 1-like", "aln": "-MNPEHRTIATRQWTRSAVAYHTRSTAMKKRMSLKRMSTPSFQK-RRRRPSRQALGNIVGCRISHGWKEGDEPVTQWKAIVLDQLPTNPSLYLVKYDGIDCVYALELYSDERILKLKVLPHKVVFPQVKDAHLASAMVARAVEHKFENKHGSKDNWRGVVLAQVPIMKDWFYITYEIDPVLYIYQLLEDYAEGNLRIIPETPPAEVKSDADSDILTGQCVHYTRSDGSKKIGKVIYQVLAKPSVYFIKFDGDVHIYIYNLVEKIS-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6AJW3-1", "uniprot_id": "A0A8I6AJW3_RAT", "id": "A0A8I6AJW3-1", "name": "", "aln": "SLNTERYPQDSGPGCRG--LPHEVYSQEEENVSEEDEHTILPEAEEEEAFSP-GPGNIVGCRISHGWKEGDEPLTQWKAIVLDQPPTNPSLYLVKYDGIACVYRLELHSDERILKLNVLTHKVVFPQVKDAHLVSAMVGRAVEHKFEGKHGCKDNWRGVVLVEVPIMKDRFYITYEKDPVLYIYQLLDDYTEGNLRIIPETPPAEVKSDVDSDILSGQCVQFTRSDGSKQIGKVIYQVPAKPSVYFNKFDGDVHIYIYNLVEKIR-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P13675-1", "uniprot_id": "SSTY1_MOUSE", "id": "P13675-1", "name": "Y-linked testis-specific protein 1", "aln": "-------------------------------MS-------SLMKKRRRKSSSNTLRNIVSCRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYFVKYDGIDSIYVLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHKFERKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPALYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANPSVYFIKFHGDIHIYVYTMVPKILEVEKS", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* ... * :**.*****.****:**:******:*** ****** :****** .:* * *:**:***.*:**. ******:.***. *:*.*.*:**** *...: ****** :* ***: * ***: *..** ****:** ****::**:***.. :*. :**:* .: *.:**.****::*:.:*** *:.**** ** *.:** ", "identical_positions": 122, "similar_positions": 58, "identity": "45.19%" }, { "cls_id": "homologset.agr.MGI:1314842", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P52191-1", "uniprot_id": "KCJ16_RAT", "id": "P52191-1", "name": "Inward rectifier potassium channel 16", "aln": "-------------------------------------------------------------------------------------MSYYGSSYRIVNVDSKYPGYPP------------------------EHAIAEKRRARRRLLHKDGSCNVYFKHIFGEWGSYMVDIFTTLVDTKWRHMFVVFSLSYILSWLIFGSIFWLIALHHGDLLSD------------PDITPCVDNVHSFTAAFLFSLETQTTIGYGYRCVTEECSVAVLTVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWRIGDFRPNHVVEGTVRAQLLRYSEDS-EGRMTMAFKDLKLVND----QIILVTPVTIVHEIDHESPLYALDRKAVA-KDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFHDVLEVKRKY--YKVNCLQFEGSVEVYAPFCSAKQLDWKDQQLNNLEKTSPARGSCTSDTNTRRRSFSAVAMVSSCENPEETSLSPQDECKEVPYQKALLTLNRISMESQM----------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z307-1", "uniprot_id": "KCJ16_MOUSE", "id": "Q9Z307-1", "name": "Inward rectifier potassium channel 16", "aln": "-------------------------------------------------------------------------------------MSYYGSSYRIVNVDSKYPGYPP------------------------EHAIAEKRRARRRLLHKDGSCNVYFKHIFGEWGSYMVDIFTTLVDTKWRHMFVIFSLSYILSWLIFGSIFWLIAFHHGDLLSD------------PDITPCVDNVHSFTAAFLFSLETQTTIGYGYRCVTEECSVAVLTVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWRIGDFRPNHVVEGTVRAQLLRYSEDS-EGRMTMAFKDLKLVND----QIILVTPVTIVHEIDHESPLYALDRKAVA-KDNFEILVTFIYTGDSTGTSHQSRSSYIPREILWGHRFHDVLEVKRKY--YKVNCLQFEGSVEVYAPFCSAKQLDWKDQQLNNLEKTSPARGSCNSDTNTRRRSFSAVAVVSSCENPEETVLSPQDECKEMPYQKALLTLNRISMESQM----------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NPI9-1", "uniprot_id": "KCJ16_HUMAN", "id": "Q9NPI9-1", "name": "Inward rectifier potassium channel 16", "aln": "-------------------------------------------------------------------------------------MSYYGSSYHIINADAKYPGYPP------------------------EHIIAEKRRARRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFSLSYILSWLIFGSVFWLIAFHHGDLLND------------PDITPCVDNVHSFTGAFLFSLETQTTIGYGYRCVTEECSVAVLMVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWRIGDFRPNHVVEGTVRAQLLRYTEDS-EGRMTMAFKDLKLVND----QIILVTPVTIVHEIDHESPLYALDRKAVA-KDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVLEVKRKY--YKVNCLQFEGSVEVYAPFCSAKQLDWKDQQLH-IEKAPPVRESCTSDTKARRRSFSAVAIVSSCENPEETTTSATHEYRETPYQKALLTLNRISVESQM----------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B7L6-1", "uniprot_id": "A0A8M3B7L6_DANRE", "id": "A0A8M3B7L6-1", "name": "", "aln": "-------------------------------------------------------------------------------------MNSGKVQYSGVKSSDNIQSVVT------------------------DDSCYSK---KKRYVRKDGSCNMVPRHVPEKWLLWVTDIFTTLVEIRWRVMLLTFALSYILSWLFFGILFWIIALTHGDMKN-------------PNNEPCVYEVRSFTAAFLFSLETQTTIGYGFRGMSENCMIAIIVVTIQDVISVFIDTFVIGIAVAKMASARKRAQTVGFSKCAVISIHDGHLCLSWRVGDFRRNHMVEGTSNAQLIEFQANNNTGKVDITYKDLIIEER----SVILATPTTIIHKILPGTPLYKMSLKDLR-KESFELVVSFTYTDDCTGILHQTRTSYTPSEILWGQNFQEMIRVTRKN--YRVDYALFNHTVKVLVPELSAEEYDLKKYSEQ--PKHKPLHISSPTP---------AVELVNGN-NLEAEKASTSSAVQEHKL--------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4LHI9-1", "uniprot_id": "A0A0B4LHI9_DROME", "id": "A0A0B4LHI9-1", "name": "", "aln": "------------------------------MRFNFSTHSAAPTSTTIPT--------TTQANGGEQATQPLKKAIEADPDSLDSVISNP-QSYPITIVPNRPTSYYG-----LSQNGKPFPRQPSCRSRNFRPG--SMRRVRRRAVFKNGDCNVVQKHLQRRRVRFLQDMYTTMVDWQWRWTLLAFALSFILSWLFFALIWWLIIYTHGDLEEPHLPENQ----EESGWAPCVSAIDGFTSCFLFSIETQHTIGYGVRTTSPECPEAIFMMCFQSIYGVMSSAFMAGIVFAKMTRAKQRAQTLLFSKHAVICQRDGTLSLMFRVGDMRKSHIIGAGVRAQLIRTKSTKEGEVMTQYFTELEIGTDDSGSDLFFIWPMVIEHKIDENSPLYNLNATDML-QDKFEIVVILEGTVESTGQSTQARSSYINTEILWGHRFDPVVLYNKDLQAYEIDYARFNETTQVDTPLCSARELNEIYKIQEGFRTPAETTFTMRQLSH------------NHSDQAS-----------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A0B4KH86-1", "uniprot_id": "A0A0B4KH86_DROME", "id": "A0A0B4KH86-1", "name": "", "aln": "MPKMIVDKSELVGENAWAKLLPDEKDKAIIVKMNKSSSNNNDSKETTPLNVDQLVAASNPAVAGEQSAVCLEDTYKRTSTYASNINSTGGESSGSGTQLSRKESILGSFHRQIRRSIKAVSESPGPLTR-YRQTRFSSRRVRKRVVFKHGECNVVQGNVAKRRRRYLQDIFTTLVDAQWRWTLLVFAASFVFSWAFFGFIWWIIAYAHNDLEYTNLKNQSPDLVANITHTVCVTQVSNMMSAFLYSVETQTTIGYGNRYVTEECPEAIFTMCIQCITGVFIQAFMVGIVFAKLSRPKKRAQTLLFSRNAVICHRDGVPCLMFRVGDMRKSHIIEAHVRAQIIRKKVTKEGEVLPFYQQELHIGADGGEDRLMFIWPTTIVHKIDRNSPLYMLSASDML-KERFEVVVMLEGVIESTGMTTQARSSYLPSEVLWGHRFVNVVSFRKETGEYEVDYTLFNNTYDVDTPLCSAKQLDELKSEYSKSAKCVNAPFADRTLSASLFQRIASAASVDHLDPASDESLDSGRLQIRSHSIPNGVLASELEPLNNNKHGASFTMGGLTITTTAPSIPNLSSINEKTNSGNSINSSNYSNNNSLSTLTGGGSAASGPGGGITIVAGSGNHGGAGGGGGGGGRHKSNPRRLSIKQDQLPIDSIC", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "B7YZX2-1", "uniprot_id": "B7YZX2_DROME", "id": "B7YZX2-1", "name": "", "aln": "-------------MQSDASPLGAAATDSLTMHRSTSMPVKPKPLEQKPLLRSSEKETVNASDYYPESPGFVRRRRSKAAGDHLETRSEQNPTFSFPYAHDWAGSTIELTP--------------DLGSGPRTSSSDGLRRSLNRVMEKNGKENVVFRRIPEKSWRYMRDLVTTLMELEWKYMLTLFLGSYFLSWLLFAALCYVVAYSHGDFIFDPVSGKRMG----EGVDPCIYGVHSWVAMIIYSVETQTTLGFGEKYASEECPETIFLFVMQMLSAALIEGCMVSVIYAKTARPARQLTKLKFSDKAVICYRDGRLCLLFRVCDPREQQSIESKIRVYIIVDKRTREGETIKSHVELKLEGNG----EQIILWPDVVCHVIDETSPLSQFTTAKLFNAAQFELYVSIVGTSPATAQMTEAKTSYLPREIFWGQRFVNIIHYDAQNERYIVDYENFNRTISVDMPMTNPKNDHLKLEYRK-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . .* : *.*. *: .: . :: *: **::: .*: : * *:.:** :*. : ::: *.*: *: : . . :::*:*** *:*:* : : :* ::: . :* : . : . : . ** : . :: .: ** *:* :** .* :*: * * .: : . .. :: : :: * .: * * :** : : **: * : . .*. ::::** *::**:.* :: . * :: *: : .* * ...: . ", "identical_positions": 56, "similar_positions": 107, "identity": "8.56%" }, { "cls_id": "homologset.agr.MGI:1314872", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QZR5-1", "uniprot_id": "HIPK2_MOUSE", "id": "Q9QZR5-1", "name": "Homeodomain-interacting protein kinase 2", "aln": "MAPVYEGMASHVQVFSPHTLQSSAFCSVKKLKVEPSSNWDMTGYGSHSKVYSQSKNIPPSQPASTTVSTSLPIPNPSLPYEQTIIFPGSTGHIVVTSASSTS-VTGQVLG---------GPHNLMRRSTVSLLDTYQKCGLKRKSEEIEN------TSSVQIIEEHPP---MIQNN-ASGATVATATTS---TATSKNSGSNSEGDYQLVQHEVLCSMTNTYEVLEFLGRGTFGQVVKCWKRGTNEIVAIKILKNHPSYARQGQIEVSILARLSTESADDYNFVRAYECFQHKNHTCLVFEMLEQNLYDFLKQNKFSPLPLKYIRPVLQQVATALMKLKSLGLIHADLKPENIMLVDPSRQPYRVKVIDFGSASHVSKAVCSTYLQSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWPLYPGASEYDQIRYISQTQGLPAEYLLSAGTKTTRFFNRDTDSPYPLWRLKTPDDHEAETGIKSKEARKYIFNCLDDMAQVNMTTDLEGSDMLVEKADRREFIDLLKKMLTIDADKRVTPIETLNHPFVTMTHLLDFPHSAHVKSCFQNMEICKRRVNMYDTVNQSKTPFITHVAPSTSTNLTMTFNNQLTTVH----NQAPTTSSATLSLANPEVSILNYQSALYQPSAASMAAVAPRSMPLQTGTAQICAR-PDPFQQALIVCPPGFQGLQASPSKHAGYSVRMENAVPIVTQAPGAQPLQIQPGLLAQQAWPGGAQQILLPPAWQQLTGVATHTSVQHAAVIPETMAGTQQLADWRNTHAHGSHYNPIMQQPALLTGHVTLPAAQPLN--------VGVAHVMRQQPTSTTSSRKSKQHQSSVRNVSTCEVTSSQAISSPQRSKRVKENTPPRCAMVHSSP--ACSTSVTCG---WG-DVASS------------------------TTRERQ------RQTIVIPDTPSPTVSVITISSDTDEEEEQKHAP-TSTVSKQRKNVISCVTVHDSPYSDSSSNTSPYSVQQRTGH-------------------NGTNTLDTKGG-LENHCTGNPRTIIVPPLKTQASEVLVECDSLGPA--------ISASHHSSSFKSKSSSTVTSTSGHSSGSSSGAIAYRQQRPG-----PHFQQQQPLNLSQAQQHMAADRTGS---------------HRRQQAYITPTMA-QAPYTFPHNSPSHGTVHPHLAAAA---HLPTQ---------PHLYTYTAPTALGSTGTVAHLVASQGSARHTVQHTAY------------------PASIVHQVPVSMGPRVLPSPTIHPSQYPAQFAHQTYISASPASTVYTG-----------------------YPLSPAKVNQYPYI----------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H2X6-1", "uniprot_id": "HIPK2_HUMAN", "id": "Q9H2X6-1", "name": "Homeodomain-interacting protein kinase 2", "aln": "MAPVYEGMASHVQVFSPHTLQSSAFCSVKKLKIEPSSNWDMTGYGSHSKVYSQSKNIPLSQPATTTVSTSLPVPNPSLPYEQTIVFPGSTGHIVVTSASSTS-VTGQVLG---------GPHNLMRRSTVSLLDTYQKCGLKRKSEEIEN------TSSVQIIEEHPP---MIQNN-ASGATVATATTS---TATSKNSGSNSEGDYQLVQHEVLCSMTNTYEVLEFLGRGTFGQVVKCWKRGTNEIVAIKILKNHPSYARQGQIEVSILARLSTESADDYNFVRAYECFQHKNHTCLVFEMLEQNLYDFLKQNKFSPLPLKYIRPVLQQVATALMKLKSLGLIHADLKPENIMLVDPSRQPYRVKVIDFGSASHVSKAVCSTYLQSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWPLYPGASEYDQIRYISQTQGLPAEYLLSAGTKTTRFFNRDTDSPYPLWRLKTPDDHEAETGIKSKEARKYIFNCLDDMAQVNMTTDLEGSDMLVEKADRREFIDLLKKMLTIDADKRITPIETLNHPFVTMTHLLDFPHSTHVKSCFQNMEICKRRVNMYDTVNQSKTPFITHVAPSTSTNLTMTFNNQLTTVH----NQAPSSTSATISLANPEVSILNYPSTLYQPSAASMAAVAQRSMPLQTGTAQICAR-PDPFQQALIVCPPGFQGLQASPSKHAGYSVRMENAVPIVTQAPGAQPLQIQPGLLAQQAWPSGTQQILLPPAWQQLTGVATHTSVQHATVIPETMAGTQQLADWRNTHAHGSHYNPIMQQPALLTGHVTLPAAQPLN--------VGVAHVMRQQPTSTTSSRKSKQHQSSVRNVSTCEVSSSQAISSPQRSKRVKENTPPRCAMVHSSP--ACSTSVTCG---WG-DVASS------------------------TTRERQ------RQTIVIPDTPSPTVSVITISSDTDEEEEQKHAP-TSTVSKQRKNVISCVTVHDSPYSDSSSNTSPYSVQQRAGH-------------------NNANAFDTKGS-LENHCTGNPRTIIVPPLKTQASEVLVECDSLVP---------VNTSHHSSSYKSKSSSNVTSTSGHSSGSSSGAITYRQQRPG-----PHFQQQQPLNLSQAQQHITTDRTGS---------------HRRQQAYITPTMA-QAPYSFPHNSPSHGTVHPHLAAAAAAAHLPTQ---------PHLYTYTAPAALGSTGTVAHLVASQGSARHTVQHTAY------------------PASIVHQVPVSMGPRVLPSPTIHPSQYPAQFAHQTYISASPASTVYTG-----------------------YPLSPAKVNQYPYI----------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B5J6-1", "uniprot_id": "A0A8M2B5J6_DANRE", "id": "A0A8M2B5J6-1", "name": "non-specific serine/threonine protein kinase", "aln": "MAPVYEGMASQVQVFSPHTLQSSAFFSVKKLKVEQSCNWDMTGYGTHSKVYSQNSKQSVSVAPVGINGASLQVSNSSLSYEQALLFPAGSGHIVVASASSTSGAAGQLLGSTGSSGSGSGGHNLTRRSTVSLLDTYQRCGLKRKSEELDNNNGSGSGSSVHVVEEQQPPAPMIQNNVQSGATVATATAST--TATSKNSGANSEGDYQLLQHEVLCSMTNTYEVLEFLGRGTFGQVVKCWKRGTSEIVAIKILKNHPSYARQGQIEVSILARLSTESADDYNFVRAYECFQHKNHTCLVFEMLEQNLYDFLKQNKFSPLPLKYIRPILQQVATALMKLKSLGLIHADLKPENIMLVDPARQPYRVKVIDFGSASHVSKAVCSTYLQSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWPLYPGASEYDQIRYISQTQGLPAEYLLSAGTKTTRFFNRDPDSTYPLWRLKTPEDHEAETGIKSKEARKYIFNCLDDMAQVNMTTDLEGSDMLAEKADRREFIDLLTKMLTIDADKRITPIETLNHPFVTMTHLLDFPHSTHVKSCFQNMEICKRRVNMYDTVNQSKTPFITHVAPSTSTNLTMTFNNQLNTVHSQATNLAPSSTSATLSLTNPDVSILNYQSALYQPSAAPMAAVAPRTMPLQPGAPQLCAARPDPFQQALIVCPPGFQGLQASPSKHTGYSVRMENAVPIVTQAPGAQPLQIQPGLLTQQAWPSGTQQILLPPAWQQLT----HTSVQHATVIPDSMTSSQPLANWRNSHPHGSHYNPIMQQPALLAGHVTLPPQQPLN--------VGVAHVMRQPSNNQSNSKKNKQHQMNNRNMSAYDVSSTQPVTSPQRSKRVKENTPPRCAVVQNGPPSTCVPSQTCTGGGWGGEQACS------------------------TTRDHHGQHNPPRQTIIIPDTPSPAVSIITISSDTDEEDDLKQPTNTSTSSKQRKNVISCVTVHDSPDSDSS-NTSPYAVDSRTNG-------------------PNANGYDSKGAVLDNYSNGNPRTIIIPPLKSQTSENLGECDRLLP---------DVMNHQNSTYKFKTSNGGFSGNNHTSGGVTGGGAYRQQRTG-----PHPFQQQPLNLSQAQQHMAVERNGG---------------HRRQQAYITPTMATQAQYSFHNSPTHTANVHPHLAAPH----LPGQ---------PHLYTYTAPAALGSTGTVAHLVASQGSARHAVQHASY------------------PPGIVHQVPVSMGHRVLPSPTLHHGQYQAQFAHQTYISASPASTVYTG-----------------------YPLSPTKMNQYPYL----------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A6M3Q6U2-1", "uniprot_id": "A0A6M3Q6U2_DROME", "id": "A0A6M3Q6U2-1", "name": "non-specific serine/threonine protein kinase", "aln": "MKTSYPPKASDFVDYAVAGGGGSGFCSG-------------LGAGLSVRATSFYGDQTVTATTDGTRHQEQQQQQLQQQQQQHILRQPATSASTSSVAAAAT-----------------SKRKRQTDCDCGCVDSYNSSHGPPVQQDSSAAAGAGSVGSKAGSGPGPDGIGPISSLKTAHTKVATSGGHANTQPPSKRSSSGADGDYQLVQHEVLYSLSAEYEVLEFLGRGTFGQVVKCWKRGTSEIVAIKILKNHPSYARQGQIEVSILSRLSQENADEFNFVRAFECFQHKNHTCLVFEMLEQNLYDFLKQNKFSPLPLKYIRPILEQVLTALLKLKQLGLIHADLKPENIMLVDPVRQPYRVKVIDFGSASHVSKTVCNTYLQSRYYRAPEIILGLPFCEAIDMWSLGCVVAELFLGWPLYPGSSEFDQIRYISQTQGLPTEHMLNSASKTSKFFYRDVDSTYPFWRLKTTEEHEAETNTKSKEARKYIFNCLDDIGQVNVPTDLEGGQLLAEKTDRREFIDLLKRMLTIDQERRLTPAEALNHSFTRLTHLVDYVYCNNVKASVQMMEVCRRGD---FHTVQPASTLVTNFVPSSTENMTFTINNQLTSQVQR-------LVRDGRPLAYEGLYQIYNGRSVARQYPQTRTDSFQHQLVSNILCPPSYQTMPSPTKHVVVGSATMQPPLQVPPQQYVNVPVPVS----MVEPTSGQRMLLTNRVQASGVAWPQTGRQMALVPSWPQQAPAHSLIVDSTPLFNVEEIYPKHHLNLPRNDLKKESPAHHIAKGNSYRVPRHEKKEHQQLSPVKKRVKESSPPHQQRYQRAAHVSPQYHAHHNCNYGNGSGYSASAGSVVASSAASSSNIVNGSSSSSHHHHVPVAHAQPYSSSSGHHIVSNCNANGGAGGAVVYQQPPAHAHQQHGQQPHPQSSQHPQHVKQPTITIHDTPSPTAVITISDSEDEGGEAGGAQVPVLKQRAHAQSQTSGSLLQHAPSSSCSRSSAHQQPHPHPQQQQQQQINYGDHDPEDARRRHHAAAAAAVGSPKHHHHQQQQQPAPPPQQQQQQYQPQPPPQQVLPQPQPSIKYEPGQSQKKRILAMAQSECGYQPQVPSQPSSSASLPHIPTKQEPAEFYPEYAAAPPQQLDTKRSSWAPTSSGSGVSALPLAHPKREAPSVAPISYVAPSVAPPLAHSKSSSASSSSSISAATAAAAAAAAAAAASVGPPSWGPPQVYRQPSQPPPGSVGLPGSTQPPPSSVAPHPHHHSHGHHHHQAGTPLGGSPSSTAAAALLQPDIYAQGDIYRRPTVFVSQAAPSYAYANRAVVAPPPAHNSSSRQVIPSHPLPAHIQIPTQYSQFGPLSPAQVAASKHAAHFAPTNIXSFVASGEAGDNPEQSQELQQHQLQLTQCWWFMLLMQQTIIQNNSIFQAGSDDAAATAAASSDTTTTRKARRQH", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P14680-1", "uniprot_id": "YAK1_YEAST", "id": "P14680-1", "name": "Dual specificity protein kinase YAK1", "aln": "-----------------------------------------MNSSNNNDSSSSNSNMNNSLSPTLVTHSDASMGSGRASPDNSHMGRGIWNPSYVNQGSQRS-----------------------------PQQQHQNHHQQQQQQQQQQ------------------------------------------QQNSQFCFVNPWNEEKVTNSQQNLVYPPQYDDLNSN------ESLDAYRRRKSSLVVPPARAPAPNPFQYDSYPAYTSSNTSLAGNSSGQYPSGYQQQQQQ-----VYQQGAIHPSQFGSR----FVPSLYDRQDFQRRQSLAATNYSSNFSSLNSNTNQGTNSIPVMSPYRRLSAYPPSTSPPLQPPFKQLRRDEVQGQKLSIPQMQLCNSKNDLQPVLNATPKFRRASLNS--------KTISPLVSVTKSLITTYSLCSPEFTYQTSKN--PKRVLTKPSEGKCNNGFDNINS---------------------------------DYILYVNDVLGVEQNRKYLVLDILGQG--TFGQVVKCQNLLTKEILAVKVVKSRTEYLTQSITEAKILELLNQKIDPTNKHHFLRMYDSFVHKN---------HLCLVFELLSNNLYELLKQNKFHGLSIQLIRTFTTQILDSLCVLKESKLIHCDLKPENILLCAPDKPELKIID--------------------FGSSCEEARTVYTYIQSRFYRAPEIILGIPYSTSIDMWSLGCIVAELFLGIPIFPG------------ASEYNQLTRIIDTLG------------------------YPPSWMIDMGKNSGKFMKKLAPEESSSSTQKHRMKTIEEFCREYNIVEKPSKQYFKWRKLP------------------------------------------------------------------------DIIRNYRYPKSIQNSQELIDQEMQNRECLIHFLGGVLNLNP--------------------------------------------------LERWTPQQAMLHPFITKQEFTGEWFPPGSSLP-----------GPSEKHDDAKGQQSEYGSANDSSNNAGHN-------------------------------------------------------------------------YVYNPSSATGGADSVDIGAIS------------------KRKENTSGDISNNFAVTHSVQEGPTSAFNKLHIVEE-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . * . : .. . . :: : . .: : : :: .:: . *: . .. .: :: : : . *: *: : :..::* ...:*. *. : .. . :. * . .. :: .:: *:: *:: : :* .: :* * * ::: : . . .: : :.:: * .*** *:* :. . :.. * : :*:: : . : * .* . : ** .:. . : . . :..* : .. * *....: :.:.. .. :: ::* :. :* :: ::: : *.: : :::. : : .: . ::.: .:. : : : :.: * : : . : : . . :: ... *: * . : :: * .: . : * : : : : .. :: . * . . : . . : . : * : . : . :: * .. : : : . : ..: *. . .. . . : ... . .* : .: .. . *. : ", "identical_positions": 43, "similar_positions": 238, "identity": "2.96%" }, { "cls_id": "homologset.agr.MGI:1314873", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88904-1", "uniprot_id": "HIPK1_MOUSE", "id": "O88904-1", "name": "Homeodomain-interacting protein kinase 1", "aln": "MASQLQVFSPPSVSSSAFCSAKKLKIEPSGWDVSGQSSNDKYYTHSKTLPATQGQASSSHQVANFNLPAYDQGLLLPAP--AVEHIVVTAADSSG-------SAATATFQSSQTLTHRSNVSLLEPYQKCG-LKRKSEEVESNGSVQIIEEHPPLMLQNRT------VVGAAATTTTVTTKSSSSSGEGDYQLVQHEILCSMTNSYEVLEFLGRGTFGQVAKCWKRSTKEIVAIKILKNHPSYARQGQIEVSILSRLSSENADEYNFVRSYECFQHKNHTCLVFEMLEQNLYDFLKQNKFSPLPLKYIRPILQQVATALMKLKSLGLIHADLKPENIMLVDPVRQPYRVKVIDFGSASHVSKAVCSTYLQSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWPLYPGASEYDQIRYISQTQGLPAEYLLSAGTKTTRFFNRDPNLGYPLWRLKTPEEHELETGIKSKEARKYIFNCLDDMAQVNMSTDLEGTDMLAEKADRREYIDLLKKMLTIDADKRITPLKTLNHQFVTMSHLLDFPHSSHVKSCFQNMEICKRRVHMYDTVSQIKSPFTTHVAPNTSTNLTMSFSNQLNTVHN--------------------------------------------------------------------------------------------QASVLASSSTAAAATLSLANSDVSLLN-------------------YQSALYPSSAAPVPG-----------------------VAQQGVSLQPGTTQICTQTDPFQQTFIVCPPAFQTGLQATTKHSGFPVRMDNAVPIVPQAPAAQPLQIQSGVLTQGSCTPLMVATLHPQVATITPQYAVPFTLSCAAGRPALVEQTAAVLQAWPGG--TQQILLPSAWQQLPGVALHNSVQPAAVIPEAMG-------SSQQLADWRNAHSHGNQYSTIMQQPSLLTNHVTLATAQPLNVGVAHVVRQQQSSSLPSKKNKQSAPVSSKSSLEVLPSQVYSLVGSSPLRTTSSYN---SLVP-VQDQHQPIIIPDTPSPPVSVITIRSDTDEEEDNKYKPNSSSLKARSNVISYVTVNDSPDSDSSLSSPHPTDTLSALRGNSGTLLEGPGRPAADGIGTRTIIVPPLKTQLGDCTVATQASGLLSS-KTKPVASVSGQSSGCCITPTG-YRAQRGGASAVQPLNLSQNQQSSS-ASTSQERSSNPAPRRQQAFVAPLSQAPYAFQHGSPLHSTGHPHLAPAPAHLPSQPHLYT-----------YAAPTSAAALGSTSSIAHLFSPQGSSRHAAAYTTHPSTLVHQVPVSVGPSLLTSASVAPAQYQHQFATQS--YIGSSR---GSTIYTGYPLSPTKISQYSYL------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A4L9P5-1", "uniprot_id": "HIPK1_RAT", "id": "A4L9P5-1", "name": "Homeodomain-interacting protein kinase 1", "aln": "MASQLQVFSPPSVSSSAFCSAKKLKIEPSGWDVSGQSSNDKYYTHSKTLPATQGQASSSHQVANFNIPAYDQGLLLQAP--AVEHIVVTAADSSG-------SAATATFQSSQTLTHRSNVSLLEPYQKCG-LKRKSEEVDSNGSVQIIEEHPPLMLQNRT------VVGAAATTTTVTTKSSSSSGEGDYQLVQHEILCSMTNSYEVLEFLGRGTFGQVAKCWKRSTKEIVAIKILKNHPSYARQGQIEVSILSRLSSENADEYNFVRSYECFQHKNHTCLVFEMLEQNLYDFLKQNKFSPLPLKYIRPILQQVATALMKLKSLGLIHADLKPENIMLVDPVRQPYRVKVIDFGSASHVSKAVCSTYLQSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWPLYPGASEYDQIRYISQTQGLPAEYLLSAGTKTTRFFNRDPNLGYPLWRLKTPEEHELETGIKSKEARKYIFNCLDDMAQVNMSTDLEGTDMLAEKADRREYIDLLKKMLTIDADKRVTPLKTLNHQFVTMTHLLDFPHSNHVKSCFQNMEICKRRVHMYDTVSQIKSPFTTHVAPSTSTNLTMSFSNQLSTVHN--------------------------------------------------------------------------------------------QASVLASSSTAAAATLSLANSDVSLLN-------------------YQSALYPPSAAPVPG-----------------------VAQQGVSLQPGTTQICTQTDPFQQTFIVCPPAFQTGLQATTKHSGFPVRMDNAVPLVPQAPAAQPLQIQSGVLTQGSCTPLMVATLHPQVATITPQYAVPFTLSCAAGRPALVEQTAAVQQAWPGG--TQQILLPSAWQQLPGVALHNSVQPTAVIPEAMG-------SSQQLADWRNAHSHGNQYSTIMQQPSLLTNHVTLATAQPLNVGVAHVVRQQQSSSLPSRKNKQSAPVSSTSSLEVLPSQVYSLVGSSPLRTTSSYN---SLVP-VQDQHQPIIIPDTPSPPVSVITIRSDTDEEEDNKFKPSSSSLKARSNVISYVTVNDSPDSDSSLSSPYPTDTLSALRGNSGTLLEGPGRTAADGIGTRTIIVPPLKTQLGDCTGATQASGLLSSSKTKPVASVSGQSSGCCITPTG-YRAQRGGASAVQPLNLSQNQQSSS-ASTSQERSSNPAPRRQQAFVAPLSQAPYAFQHGSPLHSTGHPHLAPAPAHLPSQPHLYT-----------YAAPTSAAALGSTSSIAHLFSPQGSSRHAAAYTTHPSTLVHQVPVSVGPSLLTSASVAPAQYQHQFATQS--YIGSSR---GSTIYTGYPLSPTKISQYSYL------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q86Z02-1", "uniprot_id": "HIPK1_HUMAN", "id": "Q86Z02-1", "name": "Homeodomain-interacting protein kinase 1", "aln": "MASQLQVFSPPSVSSSAFCSAKKLKIEPSGWDVSGQSSNDKYYTHSKTLPATQGQANSSHQVANFNIPAYDQGLLLPAP--AVEHIVVTAADSSG-------SAATSTFQSSQTLTHRSNVSLLEPYQKCG-LKRKSEEVDSNGSVQIIEEHPPLMLQNRT------VVGAAATTTTVTTKSSSSSGEGDYQLVQHEILCSMTNSYEVLEFLGRGTFGQVAKCWKRSTKEIVAIKILKNHPSYARQGQIEVSILSRLSSENADEYNFVRSYECFQHKNHTCLVFEMLEQNLYDFLKQNKFSPLPLKYIRPILQQVATALMKLKSLGLIHADLKPENIMLVDPVRQPYRVKVIDFGSASHVSKAVCSTYLQSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWPLYPGASEYDQIRYISQTQGLPAEYLLSAGTKTTRFFNRDPNLGYPLWRLKTPEEHELETGIKSKEARKYIFNCLDDMAQVNMSTDLEGTDMLAEKADRREYIDLLKKMLTIDADKRITPLKTLNHQFVTMTHLLDFPHSNHVKSCFQNMEICKRRVHMYDTVSQIKSPFTTHVAPNTSTNLTMSFSNQLNTVHN--------------------------------------------------------------------------------------------QASVLASSSTAAAATLSLANSDVSLLN-------------------YQSALYPSSAAPVPG-----------------------VAQQGVSLQPGTTQICTQTDPFQQTFIVCPPAFQTGLQATTKHSGFPVRMDNAVPIVPQAPAAQPLQIQSGVLTQGSCTPLMVATLHPQVATITPQYAVPFTLSCAAGRPALVEQTAAVLQAWPGG--TQQILLPSTWQQLPGVALHNSVQPTAMIPEAMG-------SGQQLADWRNAHSHGNQYSTIMQQPSLLTNHVTLATAQPLNVGVAHVVRQQQSSSLPSKKNKQSAPVSSKSSLDVLPSQVYSLVGSSPLRTTSSYN---SLVP-VQDQHQPIIIPDTPSPPVSVITIRSDTDEEEDNKYKPSSSGLKPRSNVISYVTVNDSPDSDSSLSSPYSTDTLSALRGNSGSVLEGPGRVVADGTGTRTIIVPPLKTQLGDCTVATQASGLLSN-KTKPVASVSGQSSGCCITPTG-YRAQRGGTSAAQPLNLSQNQQSSA-APTSQERSSNPAPRRQQAFVAPLSQAPYTFQHGSPLHSTGHPHLAPAPAHLPSQAHLYT-----------YAAPTSAAALGSTSSIAHLFSPQGSSRHAAAYTTHPSTLVHQVPVSVGPSLLTSASVAPAQYQHQFATQS--YIGSSR---GSTIYTGYPLSPTKISQYSYL------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B7H4-1", "uniprot_id": "A0ACD6B7H4_DANRE", "id": "A0ACD6B7H4-1", "name": "non-specific serine/threonine protein kinase", "aln": "MASQLQVFSPPSVSSSAFCRVKKMKVESCAWDASN-EAYSSVGQYSFNP-----AAG---------LSFGTSGLVFPP--GSRGQVVVRAADSTGSLQR-GSSRRTSHNNTHHSESHSSRGHRYGVKRKNEEVESSGGGGSGSSSVQILEELSAPAFSTQTGGAG--TTGQSIPHSAPTTKSSSSNGEGDYQLVQHEILCSVSNSYEVLEFLGRGTFGQVAKCWKRGTNEIVAIKILKNHPSYARQGQIEVSILNRLSAENADEFNFVRSYECFQHKGHTCLVFEMLEQNLYDFLKHSKFSPLPLRHIRPILQQVATALMKLKCLGLIHADLKPENIMLVDPIRQPYRVKVIDFGSASHVSKAVCSTYLQSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWPLYPGASEYDQIRYISQTQGLPPEYLLSAGTKTSRFFNRGPDSSYPLWRLKTPSEHESEMGIKSKEARKYIFNCLDDMMQVNLPNHLEGTDLLAEKADRRELIDLLKRMLRLDADKRITPTKTLAHPFVTMSHLLNFPHSSHVKSCFQNMDICKRRNSSFDSG---KTLFAANTVPGTAGNLTVTFSSQLN------------------------------------------------------------------------------------------------QHSQVPS---AGG--------AVPLLN-------------------YQPALYQQATINIPG-----------------------LAQPSIPLQTRSTQLCAQTEPFQQTLIVCPPTTIQGLPSSNKTSSYPVRMENGVPVVQQNQSSQPLQLQPSMLTQGSCTPLMVATLHPHPAGVASQYPLPLALGCGAGRPALLEQTATVLQAWPAG--TQQILIPSAWQQVPGMTIHNSSHQPVVNQSPLQALLS-ENSTQQTSSWRASQ--SGQHNGVVQQNPHILSGINP--THSLNRGATTATRSQN------KRSRICCDTSS----------------SSALVASQSYS---ALLT------QPIIISDTPSPAVSVITIHSDSEDEDERKFHPASCGPSHRTNVISCLTVHDS---DSSTASPLTPKPQNGHIGLQSSRLA----------KSLAVVAPTVKTQPVESSISAKIPPALGLPQNYYMKPKRAAATRHQSSSGGSISEHQQEPSRSQPLNLSQTTVSSSQAPPPGVIPSSSSLRRQHTYPP--ASSHYCLQEAPSFTST---------------PSLYT-----------YPN-----PASHMEHLLVQGS--SPSIHAPPTTHYAA--SLIPKDSIGG----VVHGISAHYQQHYPAHP--YTSTTRESGGGGAYSGYQLSPRRVPQYPYI------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M3ANW6-1", "uniprot_id": "A0A8M3ANW6_DANRE", "id": "A0A8M3ANW6-1", "name": "non-specific serine/threonine protein kinase", "aln": "MSTQMQAFSSPSVSSSGISRSKKLKVENHAWNVSNQSGESSYYQHSPSQ-----TNGSSPSTSGFNPSYNSSSLVFPPPGASREQTVVRAADSTGSVPEPSSSSSSSSTSSHRGKDARSNSLTCEGYQKRASLKRKSEEVDSSDSVQILEELSAPVLPNRVAGGGGNATAQSIAHSTSTTKSSNSHSEGDYQLVQHEILCSVSNSYEVLEFLGRGTFGQVAKCWKRGTNEIVAIKILKNHPSYARQGQIEVSILSRLSTENADEFNFVRSYECFQHKNHTCLVFEMLEQNLYDFLKHSKFSPLLLKCIRPVLQQVSTALMKLKSLGLIHADLKPENIMLVDPIRQPYRVKVIDFGSASHVSKAVCSTYLQSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWPLYPGASEYDQIRYISQTXGLPAEYLLSAGTKTSRFFHRGPDSSYPLWRLKTPAEHEADFGIKSKEARKYIFNCLDDMMQVNMTN-LEGTDILAEKADRREFIDLLKKMLTLDADKRITPTKTLNHPFVTMTHLLHFPHSSHVKSCFQNMDICKRRCTAFDNN---KNLFSSHNGPSAAANLTVTFSSQLN------------------------------------------------------------------------------------------------QHSQMAS---TGGQSLSLS-SNVPLLN-------------------YQPGLYQQATINIPG-----------------------LAQQSVPLQARPTQLCAQTEPFQQTLIVCPP-TIQGLQTTNKHTGYPVRMDNSVPIVPQNQSTQPLHIQPSMLTQFLHTSLYPFPNQSNSSSTPLTLRLPLTLSS-----RHLEQSATMLQGWPAG--TQQILIPSSWQQMSGMAMHNPSQPVLSTDSPMSSLLS-DNSNQQNS-WRGRH--GGQCDGTQQGSVQGRN-VN---TQASHAGAASARSQQNTL----KRSKVRHADNR----------------VRPTSSQQQAS---AAAHGCGDASQPIIISDTPSPAVSIITIHSDTEDEDDRKIPPESCSVNQRTNVISCVTVHDSQDSDSSTSTPISPKRQSSFI--ENNTHS----------KSLAVVTPSVKTQLWDAASGEQS-------TNSSGKSKKGMAS--QSSD----RHQRAASNRSQPLNLSQAQQSMG-----------GPLRRQPTYPPTGPSHSYRLHEASLFGSA---------------SSLYA-----------YPASAALASVSQAVDQLHNSSSTSSSRHTRTAGPYSASLSLLQKNSAMG----VMCHASAPYQQQLSAQS--YQRS----------AAFPLSQRKLNQYPYL------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A6M3Q6U2-1", "uniprot_id": "A0A6M3Q6U2_DROME", "id": "A0A6M3Q6U2-1", "name": "non-specific serine/threonine protein kinase", "aln": "---MKTSYPPKASDFVDYAVAGGGGSGFCSGLGAGLSVRATSFYGDQTVTATTDGTRHQEQQQQQLQQQQQQHILRQPATSASTSSVAAAATSKRKRQTDCDCGCVDSYNSSHGPPVQQDSSAAAGAGSVGSKAGSGPGPDGIGPISSLKTAHTKVATSGG-----------HANTQPPSKRSSSGADGDYQLVQHEVLYSLSAEYEVLEFLGRGTFGQVVKCWKRGTSEIVAIKILKNHPSYARQGQIEVSILSRLSQENADEFNFVRAFECFQHKNHTCLVFEMLEQNLYDFLKQNKFSPLPLKYIRPILEQVLTALLKLKQLGLIHADLKPENIMLVDPVRQPYRVKVIDFGSASHVSKTVCNTYLQSRYYRAPEIILGLPFCEAIDMWSLGCVVAELFLGWPLYPGSSEFDQIRYISQTQGLPTEHMLNSASKTSKFFYRDVDSTYPFWRLKTTEEHEAETNTKSKEARKYIFNCLDDIGQVNVPTDLEGGQLLAEKTDRREFIDLLKRMLTIDQERRLTPAEALNHSFTRLTHLVDYVYCNNVKASVQMMEVCRRGDFHTVQP---ASTLVTNFVPSSTENMTFTINNQLTSQVQRLVRDGRPLAYEGLYQIYNGRSVARQYPQTRTDSFQHQLVSNILCPPSYQTMPSPTKHVVVGSATMQPPLQVPPQQYVNVPVPVSMVEPTSGQRMLLTNRVQASGVAWPQTGRQMALVPSWPQQAPAHSLIVDSTPLFNVEEIYPKHHLNLPRNDLKKESPAHHIAKGNSYRVPRHEKKEHQQLSPVKKRVKESSPPHQQRYQRAAHVSPQYHAHHNCNYGNGSGYSASAGSVVASSAASSSNIVNGSSSSSHHHHVPVAHAQPYSSSSGHHIVSNCNANGGAGGAVVYQQPPAHAHQQHGQQPHPQSSQHPQHVKQPTITIHDTPSPTAVITISDSEDEGGEAGGAQVPVLKQRAHAQSQTSGSLLQHAPSSSCSRSSAHQQPHPHPQQQQQQQINYGDHDPEDARRRHHAAAAAAVGSPKHHHHQQQQQPAPPPQQQQQQYQ--------PQPPPQQVLPQPQPSIKYEPGQSQKKRILAMAQSECGYQPQVPSQPSSSASLPHIPTKQEPAEFYPEYAAAPPQQLDTKRSSWAPTSSGSGVSALPLAHPKREAPSVAPISYVAPSVAPPLAHSKSSSASSSSSISAATAAAAAAAAAAAASVGPPSWGPPQVYRQPSQPPPGSVGLPGSTQPPPSSVAPHPHHHSHGHHHHQAGTPLGGSPSSTAAAALLQPDIYAQGDIYRRPTVFVSQAAPSYAYANRAVVAPPPAHNSSSRQVIPSHPLPAHIQIPTQYSQFGPLSPAQVAASKHAAHFAPTNIXSFVASGEAGDNPEQSQELQQHQLQLTQCWWFMLLMQQTIIQNNSIFQAGSDDAAATAAASSDTTTTRKARRQH", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P14680-1", "uniprot_id": "YAK1_YEAST", "id": "P14680-1", "name": "Dual specificity protein kinase YAK1", "aln": "MNSSNNNDSSSSNSNMNNSLSPTLVTHSDASMGSGRASPDNSHMG----------------RGIWNPSYVNQGSQRSPQ---------------------------QQHQNHHQQQQQQQQQQQQNSQFCFVNPWNEEKVTNSQQNLVYPPQYDDLNSNES------LDAYRRRKSSLVVPPARAPAPNPFQYDSYPAYTSSNTS------LAGNSSGQYPSGYQQQQQQVYQQGAIHPSQFGSR---FVPSLYDRQDFQRRQSLAATNYSSNFSSLNSNTNQGTNSIPVMSPYRRLSAYPPSTSPPLQPPFKQLRRDEVQGQKLSIPQMQLCNS-----KNDLQPVLNATPKFRRASLNSKTIS---------------------------PLVSVTKSLITTYSLCSPEFTYQTSKNPKRVLTKPSEGKCNNG-------FDNINSDYILYVNDVLGVEQNRKYLVLDILGQGTFG------QVVKCQNLLTKEILAVKVVKSRTEYLTQSITEAKILELLNQKIDPTNKHHFLRMYDSFVHKNHLCLVFELLSNN------------LYELLKQNKFHGLSIQLIRTFTTQILD--------------------------------------------------------------------------------------------------------------------SLCVLK--------------------------------------------------------ESKLIHCDLKPENILLCAPDKPELKIIDFGSSCEEARTVYTYIQS----RFYRAPEIILGIPYSTSIDMWS--LGCIVAELFLGIPIFPGASEYNQLTRIIDTLGYPPSWMIDMGKNSGKFMKKLAP-----EESSSSTQKHRMKTIEEFCREYNIVEKP----------SKQYFKWRKLPDIIRNYR---------------------------------------------------------------------YPKSIQNS-------------QELIDQEMQNRECLIHFLGGVLNLNPLERWTPQQAMLHPFITKQEFTGEWFPPGSSLPGPSEKHDDAK------------------------------GQQSEYGSANDSSNNAG------HNYVYNPSSATGGADSVDIGAISKRKENTSGDISNNFAVTHSVQE-------------------------GPTSAFNKLHIVEE--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. : . . . :. . . . .. : . . . . : : : . . :* .: * . . *. .: ** . ::: .:: :: :* : *: .* . :. :. .. . *. . . : : : . :.* ::* ::*: :: : *.: : :* . . ** . .* ** **::. .* .* .*: :.* . :: : .:. *.* . . . : * :: .. .: . : *. ** * ::** *. : . * : : . . :. : . : : : .:: .: :. : : . : :: ::..*: : :: *.. : * : . . : : . .: . . : . : . . . : ::.: . * : : . . * . : . : : .. . .: . : . . . : .. . . :. ", "identical_positions": 41, "similar_positions": 195, "identity": "2.86%" }, { "cls_id": "homologset.agr.MGI:1314881", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4V8B4-1", "uniprot_id": "Q4V8B4_RAT", "id": "Q4V8B4-1", "name": "Chromatin assembly factor 1 subunit B", "aln": "MKVITCEIAWHNKEPVYSLDFQHAAACR----IQRLASAGVDTAVRIWKVEKGPDGK-------AIVEFLSNLARHTKAVNVVRFSPTGEILASGGDDAVILLWKMNDSKE-----PEQ-IAFQDEDEAQLNKENWTVVKTLRG-----HLEDVYDICWATDGNMMASASVDNTVIIWDVSKGQKISIFNEHKSYVQGVTWDPLGQYIATLSCDRVLRVYSTQKKRVAFNVSKMLSGQGPEGEAR-------SFRMFHDDSMKSFFRRLSFTPDGSLLLTPAGCMESG--ENVTNTTYVFSRE--------HLKRPIAHLPCPGKATLAVRCCPVYFELRPVAETEKASEEPSPELVSLPYRMVFAVASEDSVLLYDTQQSFPFGYVSNIHYHTLSDISWSSDGAFLAVSSTDGYCSFVTFE-KGELG--------------------------------VPLKE--KPVLGVRTPDTAKKT-------KNQ----NPQGSSPGSRSAEGTPSNRIQD-------PSSPCTTPSPTTQSPAPPAIK-------------------------------------------DSPSAIPAGKSP----------------------------------------LPRPSEEKTLQPAAQ--NMKAPQPRRVTLNTLQSWGKTAP---------------------------RRINLTPLRADTAPNPLPSSG-AAPSTEEVQ---PEVPGEPQDEPPELKRPKLEEQEGDTQSLSPDETSKSA------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D0N7-1", "uniprot_id": "CAF1B_MOUSE", "id": "Q9D0N7-1", "name": "Chromatin assembly factor 1 subunit B", "aln": "MKVITCEIAWHNKEPVYSLDFQHGATWK----IHRLASAGVDTAVRIWKLERGPDGK-------AIVEFLSNLARHTKAVNVVRFSPTGEILASGGDDAVILLWKMNDSKE-----PEQ-IAFQDEEEAQLNKENWTVVKTLRG-----HLEDVYDICWATDGNLMTSASVDNTVIIWDVSKGQKISIFNEHKSYVQGVTWDPLGQYIATLSCDRVLRIYNTQKKRVAFNISKMLSGQGPEGEAR-------SFRMFHDDSMKSFFRRLSFTPDGSLLLTPAGCMESG--ENVTNTTYVFSRK--------HLKRPIAHLPCPGKATLAVRCCPVYFELRPVAETEKASEEPSPELVNLPYRMVFAVASEDSVLLYDTQQSFPFGYVSNIHYHTLSDISWSSDGAFLAISSTDGYCTFVTFE-KGELG--------------------------------IPLKE--KPVLSIRTPDTAKKA-------KNQ----THQGSSPGSRSVEGTPSNRTQD-------PSSPCTTPSPTTQSPAPSAIK-------------------------------------------DSPSAIPAGKSP----------------------------------------LPQPSEEKTLQPAGQ--NMKAPQPRRVTLNTLQTWGKTAP---------------------------RRINLTPLKTDTVPNPQPNSG-TAPSTEEVQ---PEAPGEPPEEPPELKRPRLEEREGDAQNLAPDDSSKTV------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13112-1", "uniprot_id": "CAF1B_HUMAN", "id": "Q13112-1", "name": "Chromatin assembly factor 1 subunit B", "aln": "MKVITCEIAWHNKEPVYSLDFQHGTAGR----IHRLASAGVDTNVRIWKVEKGPDGK-------AIVEFLSNLARHTKAVNVVRFSPTGEILASGGDDAVILLWKVNDNKE-----PEQ-IAFQDEDEAQLNKENWTVVKTLRG-----HLEDVYDICWATDGNLMASASVDNTAIIWDVSKGQKISIFNEHKSYVQGVTWDPLGQYVATLSCDRVLRVYSIQKKRVAFNVSKMLSGIGAEGEAR-------SYRMFHDDSMKSFFRRLSFTPDGSLLLTPAGCVESG--ENVMNTTYVFSRK--------NLKRPIAHLPCPGKATLAVRCCPVYFELRPVVETG-------VELMSLPYRLVFAVASEDSVLLYDTQQSFPFGYVSNIHYHTLSDISWSSDGAFLAISSTDGYCSFVTFE-KDELG--------------------------------IPLKE--KPVLNMRTPDTAKKT-------KSQ----THRGSSPGPRPVEGTPASRTQD-------PSSPGTTPPQARQAPAPTVIR-------------------------------------------DPPSITPAVKSP----------------------------------------LPGPSEEKTLQPSSQ--NTKAHPSRRVTLNTLQAWSKTTP---------------------------RRINLTPLKTDTPPSSVPTSVISTPSTEEIQ---SETPGDAQGSPPELKRPRLDENKGGTESLDP-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7EYR2-1", "uniprot_id": "E7EYR2_DANRE", "id": "E7EYR2-1", "name": "Chromatin assembly factor 1 subunit B", "aln": "MKVVTCEIAWHNKEPVYSLDFQQSGDGK----TQRLATAGVDTTVRMWRVDKGPDGK-------AVVEFLSNLARHTKAVNVVRFSPTAEVLASGGDDAAILLWKLNDNKE-----PEQTPTFQEEEDAQLNKESWSVVKTLRG-----HIEDVYDISWTSDGNFMASGSVDNTAIMWDVNKGQKMCIFNDHKSYVQGVAWDPLGQYISTLSCDRVMRVYSAHNRKKAYSISKMTSSATADGEVK-------NYRMFHDDSMRSFFRRLTFTPDGSFLLAPAGCVEAG--ENVTNTTYVFSRK--------SFKRPIAHLPCPSKATLAVRCSPVYFELR-TKRAEDDSLKPVANTFNLPYRLVFAVASEDSIFFYDTQQTLPFGYVSNIHYHTLSDLSWSRDGSFLAVSSTDGYCSFISFD-EGELG--------------------------------TPLKE--KPPLEMVTPSSTNEK-------KGKRALANGRTASPVPRQAN-TPAAQDKEKEGSAGPASSKTSSVSGTEEKRTPQALKTKAQPRRITLNTLEGWGKP------------------------STPKSPAAASST----------------------------------------APSTPKSAPSTPGSSRAPLTPHTAPSTPLGPLNSKNGTTPKG----------------------PTPRRISLTPVVSKSPAAFVPPSS--TEKAKHER---PSPSSDPACKPPESKRSKTDVPDGSVQSSKNKEATEITVKPKEP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z898-1", "uniprot_id": "A1Z898_DROME", "id": "A1Z898-1", "name": "", "aln": "MKCKIPEISWHNRDPVLSVDIQQNGLGLRSPTICRLASGGSDAHVLIWYVNRSDDAEG------VDVELAADLSRHQRAVNAVRWSPNGELLASGDDESVVFIWKQKADHE-----VVN--IVDADGCSEQDKEVWLTLKVLRG-----HREDIYDLSWAPNSQFLVSGSVDNTAMLWDVHSGKSLAILDDHKGYVQGVAWDPCNQYIATMSTDRQMRIFDANTKRVLHRVSKCVLPVKEDHEMHGK-----SMRLYQDGTLQTFFRRLCFTPDGKLLLTPSGITDYDGVVKPINTSYGFSRH--------DLSKPAFVLPFPKEYAVAVRCSPVLYRLRPYNAEKN------PPIISLPYRMIYAVATKNAVFFYDTQQPVPFAIVSNIHYSRLTDLAWSSDGTVLIVSSTDGYCSLITFE-PTELGDCYEDMETVLSVVLKSSENATVLKKKRQKLRKVSLDEPRKPLQEKSKPNTIRRASEAGITEVGEPELDAENDSSTHSVSSNKTNSPKTKASEEEKPTPIAIRRSPRKNSTAPMPIAIRRAPRKPEDKGNSESSKPKDEMEVTHTKTTQVQKTVASPVKRKVSTEAVPPAETSQPALAVIPVFEKEIISSDDKFESPEKKSRPATPIQVRRQPRTPGSSSQFNLTPKSQPAKQATPIAVRRTPRVLIEMPVNSPVVPMEEAMDAWPLDESITPLPATKKDSRKPLPETVKTETKPAVIEASEATCERTEDIRLVYEDTQEETPKNPTESGPSTPNNKTPRRVSLRTISTPKSKKKLLE-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04199-1", "uniprot_id": "CAF1B_YEAST", "id": "Q04199-1", "name": "Chromatin assembly factor 1 subunit B", "aln": "MEASHLQIYWHDSQPVYSLTFQKNSAND------KLFTAGGDNKVRIWKLNRDENGQNGGVRKIESLDFLGSLTHHEQAINVIRFNSKGDVLASAGDDGQVLLWKQEDPNTQQESVVRPFGMDAETSEADENKEKWVVWKRLRGGSGATAAAEIYDLAWSPDNRNIVVACMDNSIRLFDVGAGMLVCGQSDHGHYVQGVAWDPLNQFILSQSADRSLHVYGVILSSAGVVTGLKLRSKIAKAELPCPGDVLRTNYLFHNETLPSFFRRCSISPCGGLVVIPSGVYKVAG-DEVANCVYVYTRSGILNSAGGVKNRPAIRIPSLKKPALMAAFSPVFYETC------------QKSVLKLPYKLVFAIATTNEVLVYDTDVLEPLCVVGNIHYSPITDLAWSEDGSTLLISSTDGFCSYVSIDTETQFG------------------------------------SRIEPPAMHAEPLDTDES------------AVAAKNQREAGGIVNMLPVKKIPCN----------SSDSKKRRIHPTPVDL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: :* **: :** *: :*: :* :.* * * :* :::. :.: ::: ..*::* :*:*.:*:....::***..*:. :::** : : :: :** * . * *** ::**:.*:.:.. :. ..:**: ::** * :. .:* *****:*** .*:: : * ** ::::. . . * . :::: :: :**** ::* * ::: *:* . : * * ::* .:* :* : :: . .** :. ..***::::*:*: : ::.***: *: *.**** ::*::** **: * :*****:*: :::: ::* . :* * . . : : * : ", "identical_positions": 98, "similar_positions": 146, "identity": "12.47%" }, { "cls_id": "homologset.agr.MGI:1314882", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q1LUZ7-1", "uniprot_id": "Q1LUZ7_DANRE", "id": "Q1LUZ7-1", "name": "non-specific serine/threonine protein kinase", "aln": "-MASQVLVYPPHVFQTQTSAFCSVKKLKVEPRNCVYHERAYPQTYLNGRTLGIAYPTKLTASFKTRDSVIGIHRGQDFPLQTAAVQGVRRQHTITVAQQQKRGASSQEKESEHQDKGRVCSSGATRAAGRGRGVGSDSQEEGGGGQGGVDEGGGGEDEGDQEDCGGFDLNDSSHRCGLKRKSGELENLGSTMQIVEDLSMLPAMLQSNVGNPPVAVPQAVGGGPAKQGGGSGNGDGDYQLVQHEMLCSLKNTYEVLDFLGRGTFGQVVKCWKRGTKDIVAVKILKNHPSYARQGQIEVGILARLSNENADEHNLVRAFECFQHRSHTCLVFEMLEQNLYDFLKQNKFSPLPLKVIRPILQQVATALKKLKGMGLIHADLKPENIMLVDPVRQPYRVKVIDFGSASHVSKAVCSTYLQSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWPLYPGALEFDQIRYISQTQGLPGEHLLNVGTKTSRFFCRESDSPYATWRLKSTEEHETETGLKSKEARKYIFSCLDDIAHVNLVMNLEGCDLLAEKVDRAEFVALLKKMLLIDAEERIAPSDALSHPFVTMQHLLDFPHSNHVKSCFHIMDVCCSRPGSYESHSRTKAQFVRTVPSTGAASNLTLPFCKVTG---IHTQALASSAPTVMHPG--IPLQTGSAQFG--DSFQQALILCPPTIQGLPP--------------NPNKPAGYSVSMESTVPLVTQASAIQPLQIRPGVITQQGWSNR-AQQILVPTWPQVTPVAPVAPSATTLASEPVAGPQRLADWG-------------------KVHSHGNHYSSMMPHHQPLLTNPMAMSAHQPISIGIAHVVWPQPAANKRNKPSSNRC--------------------NNFMHSTNSQNVSCQSPKMVNSAKNTEEEAADCVVEAE------SEAVQEEESVCCKAEPEYEDPTVSQKQRQTIVITDSPSPAGSIISISSGTDEDGPDTQKHAL-ECKGSPDCEACQSTLNMERVCSLSSPDSTLSTSSSASEQSSASPCKRPNSMSDDE-RESGCDTVDGSPASVSSS-RADSPFLEATYINDNNQNCKATG----STETESAKLPVRTMVVPPMRVQNE---PVG-----RTVIEPSCPPKGRSGSNR-QLPYSTLLVNRQQKSTPAFPPLQP---PQQQLFGQVQHYGSSHQEWNGNYSH-RRPQAFIPPTVHSHTFTLPHGSPTHTT-HPPQSHLGVHPHTQPALLSYPPSGPLVTNAPMAHLLASPG--ATRNHVFQPAYGLSHPAGHLLHQVTVGIN-RLLPSPTIHPQGQFKP-------------LFPPHSFIAS-PAYAG------------------------FPLSPTKLNQYPYV----------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9PMR8-1", "uniprot_id": "A0A8M9PMR8_DANRE", "id": "A0A8M9PMR8-1", "name": "non-specific serine/threonine protein kinase", "aln": "-MASQVTVCPPHVYQPQTSAFCRAK--KIDPSSCVYHEK-IPRTYVVGVNLGIAHPT----------DIIPLLRFEALTSEKPCPARNFSKQTESAPQELLRRASSPYNRVASEGKLQYFSKAEVGVEEKSGDSGQNSQ---GSSR---SSGGAPEGVRRKERSGGLNSDEGTQKCGFKCKGQEIENSKSIMQIVEEHSTLPAMLPTNVGSTTAVGVAPPEQKGTGTGAVNGTGDGDYQLVQHEVLCSMKHTYEVLEFLGRGTFGQVVKCWKRGTNEIVAVKILKNHPSYARQGQIEVSILARLSGENAEEHNLVRAFECFQHRSHTCLVFEMLEQNLYDFLKQNKFSPLPLKVIRPVLQQVATALKKLKSLGLIHADLKPENIMLVDPVRQPFRVKVIDFGSASHVSKAVCSTYLQSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWPLYPGALEYDQIRYISQTQGLPGEQLLNVGTKTARFFCKESDSPYTAWRLKTTEEHEAETGLKSKEARKYIFSCLDDIGHVNLMLNMEGCDQLAEKADRREFVDLLKMMLMIDADQRIAPSDALTHPFVTMQHLMDFPHCNHVQSCFHIMDVCHLRTSIFDTLNRNKAPPLMKPVTLPSAPNITVAFNKMPS---VHSQTLPPSAPPVVHPG--IPIQTGSAQFGCNESFQQALILCPPAMQGIPS--------------NPNQPAGYSVRMENTIPLVTQAPAIQPLPMRPGVIAQQPWSNR-TPQILVPAWQQVP------PPATSLASDTVVGAQRRGDWGTTGTTAFPCLVLETKQMCWKVRPHSSHYSSVMP--QPIVPNQMAVSAHQPINIGIAHVVWPQPASNKRNKPSQNRS--------------------MNVSHFTDTQPSVCPSPKMPEMLPSVEPQTSSPERAVQ------AQVKQEPK--QTEEEESCCKTTVPNKQRESIIIRESPSPAVSVISISSGTDEEEEQAQRCSLNKCKGSPECEACTGSLNMERVCSLSSPDSSLSTSSSASAQSSPSPCKRPSSISEDDGHESGCETVDGSPPSDSSLGPHESPFPERRFLRNQNQNQEPRARRGHPNNTGLNKPAVRTVVVPPMRVLNNNHHPNNEHLAISTVFESSCQSRSRCGPGR-LSHLSTPTLPRQQKLSSSFQ-------PQPLGFGQVQHYGSCHKEWNGNYRQPRRPQAFIPPTVHGPTFPLPHGSPTHSAGHPPP----------PALLSYPPS------APVAHLLPSPCPPPAPRPVLQPAYSLVHHQG-----ISMGINHRLLPSPTLLPQGQFKA-------------LFPPHSYVAS-PAYAG------------------------FPLSPSKLSQYPYI----------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9ERH7-1", "uniprot_id": "HIPK3_MOUSE", "id": "Q9ERH7-1", "name": "Homeodomain-interacting protein kinase 3", "aln": "-MASQVLVYPPYVYQTQSSAFCSVKKLKVEPSGCVFQERTYPQIHVNGRNFGNSHPS---------------TKGSAFQTKIPFTKPRGHSFSLQAGAIVVKDTAGATKVLAAQAQQAGVEAPRAVVWRN-----------------------------------RLHFLEGPQRCGLKRKSEELENHSGAMQIVDELSILPAMLQTNMGNPVTVVTATTGSKQNCT-----SGEGDYQLVQHEVLCSMKNTYEVLDFLGRGTFGQVVKCWKRGTNEIVAIKILKNHPSYARQGQIEVSILARLSTENADEYNFVRAYECFQHRNHTCLVFEMLEQNLYDFLKQNKFSPLPLKVIRPVLQQVATALKKLKSLGLIHADLKPENIMLVDPVRQPYRVKVIDFGSASHVSKTVCSTYLQSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWPLYPGALEYDQIRYISQTQGLPGEQLLNVGTKSTRFFCRETDMSHSGWRLKTLEEHEAETGMKSKEARKYIFNSLDDIVHVNTVMDLEGGDLLAEKADRREFVNLLKKMLLIDADLRITPIETLNHPFVNMKHLLDFPHSNHVKSCFHIMDICKSPS-SCETNNHSKMSLLRPVASNGTAA-LAANFTKVGT---LRSQALTTSAHSVVHHG--IPLQAGTAQFGCGDAFHQTLIICPPAIQGIPA--------------AHGKPTSYSIRVDNTVPLVTQAPAVQPLQIRPGVLSQQTWSGR-TQQMLIPAWQQVTP---MAPAAATLTSEGMAGSQRLGDWG-------------------KMIPHSNHYNSVMP--PPLLTNQITLSAPQPISVGIAHVVWPQPATTKKNKLCQNR---------------------SNSLQNTNIPHSAFISPKIISGKE--VEEVSCVDTQDN------HTSEGEAGTCREASVRQDS--SVSDKQRQTIIIADSPSPAVSVITISSDSDDE-ETSPRPSLRECKGSLDCEACQSTLNIDRMCSLSSPDSTLSTSSSG--QSSPSPCKRPNSMSDDE-QESGCETVDGSPTSDSSG--HDSPFAENSFVEDAHQNTELGT-----CAGPEAKPAVGTAVEPPVGRESGLSVDEH-----MANTDSTCQPLRKGQPAPGKLHQPPALGARQQKPAAAFP-------QQHLNLSQVQHFGTGHQEWNGNFGH-RRQQAYIPTSVTSNPFTLSHGSPNHTAVHAHLAG-STHLGGQPTLLPYPSSASLSSAAPVAHLLASPC--TSRPMLQHPTYNISHPSG-IVHQVPVGINPRLLPSPTIH-QTQYKP-------------IFPPHSYIAASPAYTG------------------------FPLSPTKLSQYPYM----------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O88850-1", "uniprot_id": "HIPK3_RAT", "id": "O88850-1", "name": "Homeodomain-interacting protein kinase 3", "aln": "-MASQVLVYPPYVYQTQSSAFCSVKKLKVEPSGCVFQERACPQIHVNGRHFGNPLPS---------------TKGSAFQTKIPFSKPRGHSFSLQAGAIVVKDTAGATKVIAAQAQQAGVEAPRAVVWRN-----------------------------------RLHFLGGPQRCGLKRKSEELDNHSGAMQIVDELSILPAMLQTNMGNPVTVVTATTGSKQNCT-----SGEGDYQLVQHEVLCSVKNTYEVLDFLGRGTFGQVVKCWKRGTNEIVAIKILKNHPSYARQGQIEVSILARLSTENADEYNFVRAYECFQHRNHTCLVFEMLEQNLYDFLKQNKFSPLPLKVIRPVLQQVATALKKLKSLGLIHADLKPENIMLVDPVRQPYRVKVIDFGSASHVSKTVCSTYLQSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWPLYPGALEYDQIRYISQTQGLPGEQLLNVGTKSTRFFCRETDMSHSGWRLKTLEEHEAETGMKSKEARKYIFNSLDDIVHVNTVMDLEGSDLLAEKADRREFVSLLKKMLLIDADLRITPIETLNHPFVSMKHLLDFPHSSHVKSCFHIMDICKSPS-SCETNNHSKMSLLRPVASNGTAA-LAANFTKVGT---LRSQALTTSAHSVVHHG--IPLQAGTAQFGCGDAFHQTLIICPPAIQGIPA--------------AHGKPTSYSIRVDNTVPLVTQAPAVQPLQIRPGVLS-QTWSGR-TQQMLIPAWQQVTP---MAPAAATLTSEGMAGSQRLGDWG-------------------KMIPHSNHYNSVMP--PPLLTNQITLSAPQPISVGIAHVVWPQPATTKKNKLCQNR---------------------SNSLQNTNVPHSAFISPKIISGKE--VEEVSCVETQDN------HTSEGEARTCHEASVRQDS--SVSDKQRQTIIIADSPSPAVSVITISSDTDDE-ETSPRPSLRECKGSLDCEACQSTLNIDRMCSLSSPDSTLSTSSSG--QSSPSPCKRPNSMSDDE-QESGCETVDGSPTSDSSG--HDSPFAESSFVEDTPQNPELGT-----CAGTEAKPALSTAVEPPVGTERGLNVDAH-----MANTDSTCQPLTKGQPAPGKLNQPSASAARQQKPTSAFQ-------QQHLNLSQVQHFGTGHQEWNGNFGH-RRQQAYIPTSVTSNPFTLSHGSPNHTAVHAHLAG-SAHLGGQPTLLPYPPSTALSSAAPVAHLLASPC--TSRPMLQHPTYNISHPSG-IVHQVPVGINPRLLPSPTIH-QTQYKP-------------IFPPHSYIAASPAYTG------------------------FPLSPTKLSQYPYM----------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H422-1", "uniprot_id": "HIPK3_HUMAN", "id": "Q9H422-1", "name": "Homeodomain-interacting protein kinase 3", "aln": "-MASQVLVYPPYVYQTQSSAFCSVKKLKVEPSSCVFQERNYPRTYVNGRNFGNSHPP---------------TKGSAFQTKIPFNRPRGHNFSLQTSAVVLKNTAGATKVIAAQAQQAHVQAPQIGAWRN-----------------------------------RLHFLEGPQRCGLKRKSEELDNHSSAMQIVDELSILPAMLQTNMGNPVTVVTATTGSKQNCT-----TGEGDYQLVQHEVLCSMKNTYEVLDFLGRGTFGQVVKCWKRGTNEIVAIKILKNHPSYARQGQIEVSILARLSTENADEYNFVRAYECFQHRNHTCLVFEMLEQNLYDFLKQNKFSPLPLKVIRPILQQVATALKKLKSLGLIHADLKPENIMLVDPVRQPYRVKVIDFGSASHVSKTVCSTYLQSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWPLYPGALEYDQIRYISQTQGLPGEQLLNVGTKSTRFFCKETDMSHSGWRLKTLEEHEAETGMKSKEARKYIFNSLDDVAHVNTVMDLEGSDLLAEKADRREFVSLLKKMLLIDADLRITPAETLNHPFVNMKHLLDFPHSNHVKSCFHIMDICKSHLNSCDTNNHNKTSLLRPVASSSTAT-LTANFTKIGT---LRSQALTTSAHSVVHHG--IPLQAGTAQFGCGDAFQQTLIICPPAIQGIPA--------------THGKPTSYSIRVDNTVPLVTQAPAVQPLQIRPGVLS-QTWSGR-TQQMLVPAWQQVTP---LAPATTTLTSESVAGSHRLGDWG-------------------KMISCSNHYNSVMP--QPLLTNQITLSAPQPVSVGIAHVVWPQPATTKKNKQCQNRGILVKLMEWEPGREEINAFSWSNSLQNTNIPHSAFISPKIINGKD--VEEVSCIETQDN------QNSEGEARNCCETSIRQDSDSSVSDKQRQTIIIADSPSPAVSVITISSDTDEE-ETSQRHSLRECKGSLDCEACQSTLNIDRMCSLSSPDSTLSTSSSG--QSSPSPCKRPNSMSDEE-QESSCDTVDGSPTSDSSG--HDSPFAESTFVEDTHENTELVS-----SADTETKPAVCSVVVPPVELENGLNADEH-----MANTDSICQPLIKGRSAPGRLNQPSAVGTRQQKLTSAFQ-------QQHLNFSQVQHFGSGHQEWNGNFGH-RRQQAYIPTSVTSNPFTLSHGSPNHTAVHAHLAG-NTHLGGQPTLLPYPSSATLSSAAPVAHLLASPC--TSRPMLQHPTYNISHPSG-IVHQVPVGLNPRLLPSPTIH-QTQYKP-------------IFPPHSYIAASPAYTG------------------------FPLSPTKLSQYPYM----------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A6M3Q6U2-1", "uniprot_id": "A0A6M3Q6U2_DROME", "id": "A0A6M3Q6U2-1", "name": "non-specific serine/threonine protein kinase", "aln": "MKTSYPPKASDFVDYAVAGGGGSGFCSGLGAGLSVRATSFYGDQTVTATTDGTRHQE----------------------QQQQQLQQQQQQHILRQPATSASTSSVAAAATSKRKRQTDCDCGCVDSYNS------------------------------------SHGPPVQQDSSAAAGAGSVGSKAGSGPGPDGIGPISSLKTAHTKVATSGGHANTQPPSKRS---SSGADGDYQLVQHEVLYSLSAEYEVLEFLGRGTFGQVVKCWKRGTSEIVAIKILKNHPSYARQGQIEVSILSRLSQENADEFNFVRAFECFQHKNHTCLVFEMLEQNLYDFLKQNKFSPLPLKYIRPILEQVLTALLKLKQLGLIHADLKPENIMLVDPVRQPYRVKVIDFGSASHVSKTVCNTYLQSRYYRAPEIILGLPFCEAIDMWSLGCVVAELFLGWPLYPGSSEFDQIRYISQTQGLPTEHMLNSASKTSKFFYRDVDSTYPFWRLKTTEEHEAETNTKSKEARKYIFNCLDDIGQVNVPTDLEGGQLLAEKTDRREFIDLLKRMLTIDQERRLTPAEALNHSFTRLTHLVDYVYCNNVKASVQMMEVCRRGDFHTVQPASTLVTNFVPSSTENMTFTINNQLTSQVQRLVRDGRPLAYEGLYQIYNGRSVARQYPQTRTDSFQHQLVSNILCPPSYQTMPSPTKHVVVGSATMQPPLQVPPQQYVNVPVPVSMVEPTSGQRMLLTNRVQASGVAWPQTGRQMALVPSWPQQAPAHSLIVDSTPLFNVEEIYPKHHLNLPRNDLKKESPAHHIAKGNSYRVPRHEKKEHQQLS---PVKKRVKESSPPHQQRYQRAAHVSPQYHAHHNCNYGNGSGYSASAGSVVASSAASSSNIVNGSSSSSHHHHVPVAHAQPYSSSSGHHIVSNCNANGGAGGAVVYQQPPAHAHQQHGQQPHPQSSQHPQHVKQPTITIHDTPSPTAVITISDSEDEGGEAGGAQVPVLKQRAHAQSQTSGSLLQHAPSSSCSRSSAHQQPHPHPQQQQQQQINYGDHDPEDARRRHHAAAAAAVGSPKHHHHQQQQQPAPPPQQQQQQYQPQPPPQQVLPQPQPSIKYEPGQSQKKRILAMAQSECGYQPQVPSQPSSSASLPHIPTKQEPAEFYPEYAAAPPQQLDTKRSSWAPTSSGSGVSALPLAHPKREAPSVAPISYVAPSVAPPLAHSKSSSASSSSSISAATAAAAAAAAAAAASVGPPSWGPPQVYRQPSQPPPGSVGLPGSTQPPPSSVAPHPHHHSHGHHHHQAGTPLGGSPSSTAAAALLQPDIYAQGDIYRRPTVFVSQAAPSYAYANRAVVAPPPAHNSSSRQVIPSHPLPAHIQIPTQYSQFGPLSPAQVAASKHAAHFAPTNIXSFVASGEAGDNPEQSQELQQHQLQLTQCWWFMLLMQQTIIQNNSIFQAGSDDAAATAAASSDTTTTRKARRQH", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P14680-1", "uniprot_id": "YAK1_YEAST", "id": "P14680-1", "name": "Dual specificity protein kinase YAK1", "aln": "---------MNSSNNNDSSSSNSNMNNSLSPTLVTHSDASMGSGRASPDNS---------------------------HMGRGIWNPSYVNQGSQRSPQQQHQNHHQQQQQQQQQQQQNSQFCFVNPWNE------------------------------------EKVTNSQQNLVYPPQYDDLNSNES----------LDAYRRRKSSLVVPPARAPAPNP-----------------FQYDSYPAYTSSNTSLAGNSSGQYPSGYQQQQQQVYQQGAIHPSQFGSRFVP------SLYDRQDFQRRQSLAATNYSSNFSSLNSNTNQGTNSIPVMSPYRRLSAYPPSTSPPLQPPFKQLRRDEVQGQKLSIPQMQLCNS-----KNDLQPVLNATPKFRRASLNSKTIS---------------------------PLVSVTKSLITTYSLCSPEFTYQTSKNPKRVLTKPSEGKCNNG----------FDNINSDYILYVNDVLGVEQ---NRKYLVLDILGQGTFGQVVKCQNLLTKEILAVKVVKSRTEYLTQSITEAKILELLNQKIDPTNKHHFLRMYDSFVHKNHLCLVFELLSNN-----LYELLKQNKFHGLSIQLIRTFTTQILDSLCVLKE-----------------------------SKLIHCDLKPENILLCAPDKP---------------------ELKIIDFGSSCEEARTVYTYIQSRFYRAPEIILGIPYSTS-----------------------IDMWSLGCIVAELFLGIP--------------------IFPGASEYNQLTR-----IIDTLGYPPSWMIDMGKNSGKFMKKLAPEE------------------------------------------------------------------------SSSSTQKHRMKTIEEFCREYNIVEKPSKQYFKWRKLPDIIRNYRYPKSIQNSQELIDQEMQNRECLIH----FLGGVLNLNPLERWTPQQAMLHPFITKQEFTGEWFPPGSSLPGPSEKHDDAKGQQSEYGSANDSS-----------------------------------NNAGHNYVYNPSSATGG-----------ADSVDIGAISKRKENTSGDISNNFAVTHSVQEGPTSAFN-----------KLHIVEE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.. : . . . . : . . : .: . . : : : .*:: : . * . * : . : :: . : *:: : . :. .: * . :. :. .. . *. . . : : : . :.* . ::* ::*: : : :.: : :* . . ** . .* ** **::. .* .* .*: :.* . :: : .:. * * * . * . : * : .* .:: : . . :* :: : ** *. : . * : : . : .: . : .: : .:: ..::. . . : : : :: : ::*.* . . . : : :. : . .. . : .. . .. : : .. . . .: : . *. .* : . : . *: : .: . :. . . . . : . . : .:: : :. ", "identical_positions": 37, "similar_positions": 193, "identity": "2.51%" }, { "cls_id": "homologset.agr.MGI:1314883", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q80WY6-1", "uniprot_id": "TNR1B_RAT", "id": "Q80WY6-1", "name": "Tumor necrosis factor receptor superfamily member 1B", "aln": "MAPAALWVALVVELQLWATGHTVPAKVVLTPYKPEPGNQCQISQEYYDKKAQMCCAKCPPGQYAKHFCNKTSDTVCADCAAGMFTQVWNHLHTCLSCSSSCSDD-QVETHNCTKKQNRVCACNADSYCALKLHSGNCRQCMKLSKCGPGFGVARSRTSNGNVICSACAPGTFSDTTSSTDVCRPHRICS--ILAIPGNASTDAVCASESPTPSAVPRTIYVSQPEPTRSQPMDQEPGPSQTP--HIPVSLGSTPIIEPSITGGISLPIGLIVGLTTLGLLMLGLANCFILVQRKKKPSCLQRETMVPHLPDDKSQDAIGLEQQHLLTTAPSSSSSSLESSASAGDRRAPPGGHPQARVTAEAQGSQEACAGSRSSDSSHGSHGTHVNVTCIVNVCSSSDHSSQCSSQASTTVGDPDANPSGSPKDEQVPFSQEECPSQSQWETTETLQN--HDKPFPLGVPDVGMKPNQPGWYDQIAVKVP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P25119-1", "uniprot_id": "TNR1B_MOUSE", "id": "P25119-1", "name": "Tumor necrosis factor receptor superfamily member 1B", "aln": "MAPAALWVALVFELQLWATGHTVPAQVVLTPYKPEPGYECQISQEYYDRKAQMCCAKCPPGQYVKHFCNKTSDTVCADCEASMYTQVWNQFRTCLSCSSSCTTD-QVEIRACTKQQNRVCACEAGRYCALKTHSGSCRQCMRLSKCGPGFGVASSRAPNGNVLCKACAPGTFSDTTSSTDVCRPHRICS--ILAIPGNASTDAVCAPESPTLSAIPRTLYVSQPEPTRSQPLDQEPGPSQTP--SILTSLGSTPIIEQSTKGGISLPIGLIVGVTSLGLLMLGLVNCIILVQRKKKPSCLQRDAKVPHVPDEKSQDAVGLEQQHLLTTAPSSSSSSLESSASAGDRRAPPGGHPQARVMAEAQGFQEARASSRISDSSHGSHGTHVNVTCIVNVCSSSDHSSQCSSQASATVGDPDAKPSASPKDEQVPFSQEECPSQSPCETTETLQS--HEKPLPLGVPDMGMKPSQAGWFDQIAVKVA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P20333-1", "uniprot_id": "TNR1B_HUMAN", "id": "P20333-1", "name": "Tumor necrosis factor receptor superfamily member 1B", "aln": "MAPVAVWAALAVGLELWAAAHALPAQVAFTPYAPEPGSTCRL-REYYDQTAQMCCSKCSPGQHAKVFCTKTSDTVCDSCEDSTYTQLWNWVPECLSCGSRCSSD-QVETQACTREQNRICTCRPGWYCALSKQEG-CRLCAPLRKCRPGFGVARPGTETSDVVCKPCAPGTFSNTTSSTDICRPHQICN--VVAIPGNASMDAVCTSTSPTRSMAPGAVHLPQPVSTRSQHTQPTPEPSTAPSTSFLLPMGPSPPAEGS-TGDFALPVGLIVGVTALGLLIIGVVNCVIMTQVKKKPLCLQREAKVPHLPADKARGTQGPEQQHLLITAPSSSSSSLESSASALDRRAPTRNQPQAPG-VEASGAGEARASTGSSDSSPGGHGTQVNVTCIVNVCSSSDHSSQCSSQASSTMGDTDSSPSESPKDEQVPFSKEECAFRSQLETPETLLGSTEEKPLPLGVPDAGMKPS-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B2L3-1", "uniprot_id": "A0A8M2B2L3_DANRE", "id": "A0A8M2B2L3-1", "name": "", "aln": "----MLILIARLLLLFMTVVWLMAEGKIPPPFRPEKEQCNNTTSEYYMKQLGLCCSRCKPGTRLSVQCSTASDTICEPCPDGMYSENMNHYPNCFKCPTCREEKGLMYGRNCSADTKAVCVCKPGMYCSKYGLSSACEECKKYKTCKPGEGAQRKGTPTGVVKCAPCPTGTFSDRSG-SEPCRPHTECEGSAVLRSGNSTDDTVCVVKPLKATPEIWPMNTISTSTVSVLSSDVKHSSTVTTN-----AQGTRSNPPPD-----YMTIIYITGAVVLVLLILVMTVVTCKLRERKAGLTKVPITDVNTVEQDPSQSS-TPDHQHLLHVDRTQTEPSMSSSDSQSQ---PDCGQSHSSSEWLERSSQDECPSVSSP---------------VLNLSITATFNCQLNPAATSCSIPINPSTLTPHAEALVPLSQEEVCTSSCQQE--------DGKEVLKSVQESGPFLY-------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . * : :. :. .*: ** . *** : :**::* ** . *..:***:* * . ::: * *:.* : . : : *: . : :*.*... **: .. *. * .* ** *. : .. * * .*..****: :. :: **** *. : .**:: *:**. . . : .: .. .. : .: :. . *. . . :.: *.* . * **:: :. : :* : * : : ::.: ::**** . :.:..*:.** * : * .:.:: . : .. . ::*:. :: ...* .. *:: :... . : **:*:** * : . * . .* : * ", "identical_positions": 78, "similar_positions": 144, "identity": "16.22%" }, { "cls_id": "homologset.agr.MGI:1314884", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P25118-1", "uniprot_id": "TNR1A_MOUSE", "id": "P25118-1", "name": "Tumor necrosis factor receptor superfamily member 1A", "aln": "MGLPTVPGLLLSLVLLALLMGIHPSGVTGLVPSLGDREKRDSLCPQGKYVHSKNNSICCTKCHKGTYLVSDCPSPGRDTVCRECEKGTFTASQNYLRQCLSCKTCRKEMSQVEISPCQADKDTVCGCKENQFQRYLSETHFQCVDCSPCFNGTVTIPCKETQNTVCNCHAGFFLRESECVPCSHCKKNEECMKLCLPPPLANVTNPQDSGTAVLLPLVILLGLCLLSFIFISLMCRYPRWRPEVYSIICRDPVPVKEEKAG----KPLTPAPSPAFSPTSGFNPTLGFS-TPGFSSPVSSTPISPIFGPSNWH-FMPPVSEVVP-TQGADPLLYESLCSVPAPTSVQKWED--SAHPQRPDNADLAILYAVVDGVPPARWKEFMRFMGLSEHEIERLEMQNGRCLREAQYSMLEAWRRRTPRHEDTLEVVGLVLSKMNLAGCLENILEALRNPAPSS-TTRLPR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P22934-1", "uniprot_id": "TNR1A_RAT", "id": "P22934-1", "name": "Tumor necrosis factor receptor superfamily member 1A", "aln": "MGLPIVPGLLLSLVLLALLMGIHPSGVTGLVPSLGDREKRDNLCPQGKYAHPKNNSICCTKCHKGTYLVSDCPSPGQETVCEVCDKGTFTASQNHVRQCLSCKTCRKEMFQVEISPCKADMDTVCGCKKNQFQRYLSETHFQCVDCSPCFNGTVTIPCKEKQNTVCNCHAGFFLSGNECTPCSHCKKNQECMKLCLPP-VANVTNPQDSGTAVLLPLVIFLGLCLLFFICISLLCRYPQWRPRVYSIICRDSAPVKEVEGEGIVTKPLTPASIPAFSPNPGFNPTLGFSTTPRFSHPVSSTPISPVFGPSNWHNFVPPVREVVP-TQGADPLLYGSLNPVPIPAPVRKWEDVVAAQPQRLDTADPAMLYAVVDGVPPTRWKEFMRLLGLSEHEIERLELQNGRCLREAHYSMLEAWRRRTPRHEATLDVVGRVLCDMNLRGCLENIRETLESPAHSS-TTHLPR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P19438-1", "uniprot_id": "TNR1A_HUMAN", "id": "P19438-1", "name": "Tumor necrosis factor receptor superfamily member 1A", "aln": "MGLSTVPDLLLPLVLLELLVGIYPSGVIGLVPHLGDREKRDSVCPQGKYIHPQNNSICCTKCHKGTYLYNDCPGPGQDTDCRECESGSFTASENHLRHCLSCSKCRKEMGQVEISSCTVDRDTVCGCRKNQYRHYWSENLFQCFNCSLCLNGTVHLSCQEKQNTVCTCHAGFFLRENECVSCSNCKKSLECTKLCLPQ-IENVKGTEDSGTTVLLPLVIFFGLCLLSLLFIGLMYRYQRWKSKLYSIVCGKSTPEKEGELEGTTTKPLAPN--PSFSPTPGFTPTLGFSPVPSSTFTSSST-----YTPGDCPNFAAPRREVAPPYQGADPILATALASDPIPNPLQKWEDS-AHKPQSLDTDDPATLYAVVENVPPLRWKEFVRRLGLSDHEIDRLELQNGRCLREAQYSMLATWRRRTPRREATLELLGRVLRDMDLLGCLEDIEEALCGPAALPPAPSLLR", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***. **.***.**** **:**:**** **** ********.:****** *.:*************** .***.**::* *. *:.*:****:*::*:****..***** *****.* .* ******::**:::* **. ***.:** *:**** :.*:*.*****.******* .**..**:***. ** ***** : **...:****:*******::***** :: *.*: ** :*:..:***:* ...* ** : ***:* *:***..**.****** .* : . *** : *.: * .* **.* *****:* :* . * * .::**** : :** *. * * *****:.*** *****:* :***:***:***:*********:**** :*******:* **:::* ** .*:* ****:* *:* .** . :. * *", "identical_positions": 270, "similar_positions": 109, "identity": "58.19%" }, { "cls_id": "homologset.agr.MGI:1314891", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35305-1", "uniprot_id": "TNR11_MOUSE", "id": "O35305-1", "name": "Tumor necrosis factor receptor superfamily member 11A", "aln": "--------------------------------------------------------------MAPRARRRRQLPAPLLALCVLLVPLQVTLQVTPPCTQERHYEHLGRCCSRCEPGKYLSSKCTPTSDSVCLPCGPDEYLDTWNEEDKCLLHKVCDAGKALVAVDPGNHTAPRRCACTAGYHWN-SDCECCRRNTECAPGFGAQHPLQLNKDTVCTPCLLGFFSDVFSSTDKCKPWTNCTLLGKLEAHQGTTESDVVCSSSMTLRRPPKEAQAYLPSLIVLLLFISVVVVAAIIFGVYYRKGGKALTANLWNWVNDACSSLSGNKESSGDRCAGSHSATSSQQEVCEGILLMTREEKMVPE-----DGAGVCGPVCAAGGPWAEVRDSRTFTLVSEVETQGDLSRKIPTEDEYTDRPSQPSTGSLLLIQQGSKSIPPFQEPLEVGENDSLSQCFTGTESTVDSEGCDFTEPPSRTDSMPVSPEKHLTKEIEGDSCLPWVVSS-----NSTDGYTGSGNTPGEDHEPFPGSLKCGPLPQCAYSMGFPSEAAASMAEAGVRPQDRAD------ERGASGSGSSPSDQPPASGNVTGNSNSTFISSGQVMNFKGDIIVVYVSQTSQEGPGSAEPESEP--VGRPVQEETLAHRDSFAGTAPRFPDVCATGAGLQEQGAPRQKDGTSRPVQEQGGAQTSLHTQGSGQCAE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1M8Z6-1", "uniprot_id": "F1M8Z6_RAT", "id": "F1M8Z6-1", "name": "", "aln": "MPKPSPPGATAAHAWAPPGGARRRRGGRCRAEPGARGGTRRAEGGGDRGSREAVRPARPHRAMAPRARRRRQFPAPLLALCVLLLPLQVTLQVTLPCTQERHYEHLGRCCSRCEPGKYLSSKCTPTSDSVCLPCGPDEYLDTWNEEDKCLLHKVCDAGKALVAVDPGNHTAPRRCACTAGYHWN-ADCECCRRNTECAPGFGAQHPLQLNVDTVCTPCLLGFFSDVFSSTDKCKPWTNCTVLGKMEAHQGTTESDVVCSSSLTLIKPPKEAQVYLPSLIVLLLFISVVVVAAIVFSIYYRKGGKTLTANLWNWVNDACSSLSGNKESSGDHCVGSHSANSSQQEVCEGILLMTREEKMVPE-----DCAGVCGPVRAASGPWAEGRDARTFTLVSEVETQGNLSRKIPTEDEYTDRPSQPPNGSLFLIQPGSRSTPPFQEPLEVGENDSLSQCFTGTESMVDSEGCDFTEPPSRTDYMPASPEKLLTKEIEDDSCLPWVANS-----NSTDGYTGSGNTPGEDHEPLPGSLKCGPLPQCAYSIGLPSEAAASLAEVGAQPQDRADAKLPSSERGASGSGSSPSEQPPASGNVTGNSNSTFISSGQVMNFKGDIIVVYVSQTSQEGPGPAEPEPEPEPVGRPVQEETLAHRDSFAGTAPRFPDACTTGAGLQEKGASRPKDWASRPVQEQGGAQASLNTQGSGQCAE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y6Q6-1", "uniprot_id": "TNR11_HUMAN", "id": "Q9Y6Q6-1", "name": "Tumor necrosis factor receptor superfamily member 11A", "aln": "--------------------------------------------------------------MAPRARRRRPLFA-LLLLCALLARLQVALQIAPPCTSEKHYEHLGRCCNKCEPGKYMSSKCTTTSDSVCLPCGPDEYLDSWNEEDKCLLHKVCDTGKALVAVVAGNSTTPRRCACTAGYHWS-QDCECCRRNTECAPGLGAQHPLQLNKDTVCKPCLAGYFSDAFSSTDKCRPWTNCTFLGKRVEHHGTEKSDAVCSSSLPARKPPNEPHVYLPGLIILLLFASVALVAAIIFGVCYRKKGKALTANLWHWINEACGRLSGDKESSGDSCVSTHTANFGQQGACEGVLLLTLEEKTFPEDMCYPDQGGVCQGTCVGGGPYAQGEDARMLSLVSKTEIEEDSFRQMPTEDEYMDRPSQPTDQLLFLTEPGSKSTPPFSEPLEVGENDSLSQCFTGTQSTVGSESCNCTEPLCRTDWTPMSSENYLQKEVDSGHCPHWAASPSP---NWADVCTGCRNPPGEDCEPLVGSPKRGPLPQCAYGMGLPPEEEASRTEARDQPEDGADGRLPSSARAGAGSGSSPGGQSPASGNVTGNSNSTFISSGQVMNFKGDIIVVYVSQTSQEG---AAAAAEP--MGRPVQEETLARRDSFAGNGPRFPDPCGGPEGLREP------EKASRPVQEQGGAKA------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F027-1", "uniprot_id": "E7F027_DANRE", "id": "E7F027-1", "name": "", "aln": "---------------------------------------------------------------MRVIFSASWIFQGWITYFVLALCTQTGQAIS---CQQNEYVYNGRCCEKCKAGTHVLEHCNGRSKTRCFDCGFDQYQPDWNNKMYCISQKYCDEGKGFNRTRPQNPTAPEPCRCKQGFHCSLINCEYCEAIEECPP--GKGVVMGVNGRASCVSCPAGTFSDSLS-KESCKKWTDCKAIGKTEKQLGSTTTDAVCG---------LHSSGMTPWVVVAILSVIIVVSLVVLCLFCCKDKLNFLSVNLRTCVQN----LKGTRNQQETLTNSYHCSHSPQT------LPLICQELTPPE--------------------FLINCPSTHITISDELLPYTNQDQDQDCAETSSGGSSEDSGCGPSSPLSGSSCSCAPKEPVEVGENEDCSQLVATGLATCCS--CRTGDETAEHEQVIILKEPLLCDGLPACDYVHLHRSQELYLDFSSPAGKDAMSEMRDDRGLVEGSYRQNEPRCCSIDSTTIPSLLSVSDNDQGLSLIHSDEHKLSELDTDEDYQNQCSDSALTSGQVTGNNNTTFISSGQVMNFSGEVIVVYVSQTSLGS---SGGTDEP--FSCPVQEE--SNEDSLQ-NQPKSNSSTAPPAKTRNAR-----LEKQLPVQEMTSDLSWQK---------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : .* *. :: .:..* : ****.:*:.*.:: .:*. *.: *: ** *:* **:: *: :* ** **.: . . * *:*. * *. *:* . :** *. **.* * : :* : * .* * *** :* .:.*: **:*. :** : *: :*.**. .. * ::: :* :.: .:: . :. : *:.** ::: *.* ::.. . * : * * : :* ** : : ::: .: : :. : . .*: . ** . . .**:*****:. ** .: : * * : .. : * * . : . : ... . :* . ** : . *: . .. : : . :* . .. . .. :**:****.*:***********.*::********* . : ** .. ***** :..**: . *: . :: . **** . : ", "identical_positions": 132, "similar_positions": 165, "identity": "18.7%" }, { "cls_id": "homologset.agr.MGI:1315192", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V9K7-1", "uniprot_id": "G3V9K7_RAT", "id": "G3V9K7-1", "name": "Leucine-rich repeat-containing protein 23", "aln": "MSDEDDVEDDFDQEPDEVEKEEDDNEMEDWEDDYRKEGEEVSEEWLPTPLTEAMMKEGLSLLCKIGSGLAHAYIKLEVKDRDLTDISLLRSYIHLRYVDISENHITDMSPLNSLTHLLWLKADGNQLR---SARLNELPYLQIASFSYNQITDTEGIIHPRLGSLDLKGNRIHQVTGLDPERLTNLHTLELRANQLETTIGINLPKLKNLYLAQNLLKKVEGLENLSNLTTLHLRDNQIETLDGFSKEMKSLQYLNLRSNMISDLGELAKLRDL-PKLRALVLLDNPCADETDYRQEALVQMAHLERLDKEYYEDEDRAEAEEIRQRLKEEQEQELDPDQDMEPYLPPT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35125-1", "uniprot_id": "LRC23_MOUSE", "id": "O35125-1", "name": "Leucine-rich repeat-containing protein 23", "aln": "MSDEDDVDD-VDAEQDEVE---SDKEIEEWED-YRKETEEASEEWLPTPITEAMMKEGLSLLCKIGSGLAHAYIKLEAKDRDLTDISLLRSYIHLRYVDISENHITDISPLNSLTHLLWLKADGNQLR---SARMNELPYLQIASFSYNQIIDTEGIFHPRLGSLDLKGNRIHQVTGLDPERLSSLHTLELRGNQLESTKGIYLPKLKNLYLAQNLLKKVEGLENLSNLTTLHLRDNQIETLNGFSQEMKSLQYLNLRSNMISDLAELAKLRDL-PKLRALVLLDNPCADETDYRQEALVQMAHLERLDKEFYEDDDRAEAEEIRQRLKEEQDQDLDPDQDMEPYLPPV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q53EV4-1", "uniprot_id": "LRC23_HUMAN", "id": "Q53EV4-1", "name": "Leucine-rich repeat-containing protein 23", "aln": "MSDEDDLED-SEPDQDDSEKEEDEKETEEGED-YRKEGEEFPEEWLPTPLTEDMMKEGLSLLCKTGNGLAHAYVKLEVKERDLTDIYLLRSYIHLRYVDISENHLTDLSPLNYLTHLLWLKADGNRLR---SAQMNELPYLQIASFAYNQITDTEGISHPRLETLNLKGNSIHMVTGLDPEKLISLHTVELRGNQLESTLGINLPKLKNLYLAQNMLKKVEGLEDLSNLTTLHLRDNQIDTLSGFSREMKSLQYLNLRGNMVANLGELAKLRDL-PKLRALVLLDNPCTDETSYRQEALVQMPYLERLDKEFYEEEERAEADVIRQRLKEEKEQEPEPQRDLEPEQSLI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58IJL8-1", "uniprot_id": "A0AC58IJL8_DANRE", "id": "A0AC58IJL8-1", "name": "Leucine-rich repeat-containing protein 23", "aln": "MSDSG---------EDEVLKADSDHEGE-NEDLEEKEKSDG-DQLESCPLTQDILARSLSLLCRTGNGLSHAYVRLDLKNKGLTDLALLSSFIHLRYLDLSSNHLSDFSPLAGLTQLLWVKGDSNLLQGFEGQPFGQLTFLQWLSIASNRLFDVKGLGGPALETLNLTGNGIQTMQGLDYPNLTNLVTLELRGNCLETTDGIYLPNLRHLYLAQNNIKKLEGLEKLERLITLHLRHNQLETLDGLSASMKCLEYLNVRGNLISSMRALQTLASVGQTLKALVLLDNPIAKTDDYRLYVISQLPHLERVDKDPVTPEEKFEAQKKNKESQTGLEQAKGE-----------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***.. *: .::* * ** .** .: :: . *:*: :: ..*****: *.**:***::*: *::.***: ** *:*****:*:*.**::*:*** **:***:*.*.* *: . :.:*.:** *:: *:: *.:*: * * :*:*.** *: : *** .* .* *:***.* **:* ** **:*::****** :**:****.*..* *****.**::**.*:* .**.*:***:*.*:::.: * .* .: .*:******** :. .** .: *:.:***:**: ::: **: .:. : :* ", "identical_positions": 140, "similar_positions": 110, "identity": "40.11%" }, { "cls_id": "homologset.agr.MGI:1315195", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZDS4-1", "uniprot_id": "D3ZDS4_RAT", "id": "D3ZDS4-1", "name": "18S rRNA (pseudouridine(1248)-N1)-methyltransferase", "aln": "MAATSGGFQPRERRFSVQEQDWDPAPPKRPRLGAGSKCGGRRLIVVLEGASLETVKVG------KTYELLNCDKHKSMLLKNGRDPGEVRPDITHQSLLMLMDSPLNRAGLLQVYIHTQKNVLIEVNPQTRIPRTFDRFCGLMVQLLHKLSVRAADGPQKLLKVIKNPVSDHFPVGCMKIGTSFSVEDISDIRELVPS--------SDPVVFVVGAFAHG--KVSVEYTEKMVSISNYPLSAALTCAKVTTAFEEVWGVI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35130-1", "uniprot_id": "NEP1_MOUSE", "id": "O35130-1", "name": "Ribosomal RNA small subunit methyltransferase NEP1", "aln": "MSAASGGFQPRERRFSVQEQDWETTPPKKLRLGAGSKCGGRRLIVVLEGASLETVKVG------KTYELLNCDRHKSMLLKNGRDPGEVRPDITHQSLLMLMDSPLNRAGLLQVYIHTQKNVLIEVNPQTRIPRTFDRFCGLMVQLLHKLSVRAADGPQKLLKVIKNPVSDHFPVGCMKIGTSFSVEDISDIRELVPS--------SDPVVFVVGAFAHG--KVSVEYTEKMVSISNYPLSAALTCAKVTTAFEEVWGVI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92979-1", "uniprot_id": "NEP1_HUMAN", "id": "Q92979-1", "name": "Ribosomal RNA small subunit methyltransferase NEP1", "aln": "MAAPSDGFKPRERSGGEQAQDWDALPPKRPRLGAGNKIGGRRLIVVLEGASLETVKVG------KTYELLNCDKHKSILLKNGRDPGEARPDITHQSLLMLMDSPLNRAGLLQVYIHTQKNVLIEVNPQTRIPRTFDRFCGLMVQLLHKLSVRAADGPQKLLKVIKNPVSDHFPVGCMKVGTSFSIPVVSDVRELVPS--------SDPIVFVVGAFAHG--KVSVEYTEKMVSISNYPLSAALTCAKLTTAFEEVWGVI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W4J5-1", "uniprot_id": "NEP1_DROME", "id": "Q9W4J5-1", "name": "Ribosomal RNA small subunit methyltransferase NEP1", "aln": "MGGQGKAINRKRKFVGRKADDPEFDLDKKQFKVLHLNATEKRLIIVLEGAQLETVKVH------NTFELLNCDDHAGIMRKNQRDPGSCRPDITHQCLLMLFDSPLNRAGLLQVFVRTEHNVLIEINPQTRIPRTFKRFAGLMVQLLHKFQIRANDSSRRLMSVIKNPITDHVPVGCKKYAMSFSGKLLPNCRDLVPHGDETSASYDEPVVIVIGAFAHG--VLKTDYTEELFSISNYPLSAAIACSKICSAFEEVWGVV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06287-1", "uniprot_id": "NEP1_YEAST", "id": "Q06287-1", "name": "Ribosomal RNA small subunit methyltransferase NEP1", "aln": "MVEDSR-VRDALKGGDQKALPASLVPQAPPVLTSKDKIT-KRMIVVLAMASLETHKISSNGPGGDKYVLLNCDDHQGLLKKMGRDISEARPDITHQCLLTLLDSPINKAGKLQVYIQTSRGILIEVNPTVRIPRTFKRFSGLMVQLLHKLSIRSVNSEEKLLKVIKNPITDHLPTKCRKVTLSFDAPVIR-VQDYIEKLDD-----DESICVFVGAMARGKDNFADEYVDEKVGLSNYPLSASVACSKFCHGAEDAWNIL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . .. : . : . : :*:*:** *.*** *: ..: ***** * .:: * ** .. *******.** *:***:*:** ***:::*.:.:***:** .******.**.*********:.:*: :. .:*:.*****::**.*. * * **. : :: : .:.: ..:**:*:* . :*.:: ..:*******:::*:*. . *:.*.::", "identical_positions": 91, "similar_positions": 83, "identity": "35.0%" }, { "cls_id": "homologset.agr.MGI:1315196", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9R1B1-1", "uniprot_id": "T10B_RAT", "id": "Q9R1B1-1", "name": "Mitochondrial import inner membrane translocase subunit Tim10 B", "aln": "ME---HQQQQ-------LRNLRDFLLVYNRMTELCFQRCVPSLHHRALDAEEEACLHSCAGKLIHSNHRLMAAYVHLMPALVQRRMADYE-------------AASAVPGVPAE-----------------------------QPRDSP------------SGS-------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WV96-1", "uniprot_id": "T10B_MOUSE", "id": "Q9WV96-1", "name": "Mitochondrial import inner membrane translocase subunit Tim10 B", "aln": "ME---QQQQQ-------LRNLRDFLLVYNRMTELCFQRCVPSLHHRALDAEEEACLHSCAGKLIHSNHRLMAAYVHLMPALVQRRIADYE-------------AASAAPGIPAE-----------------------------QTRDSP------------SGS-------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y5J6-1", "uniprot_id": "T10B_HUMAN", "id": "Q9Y5J6-1", "name": "Mitochondrial import inner membrane translocase subunit Tim10 B", "aln": "MERQQQQQQQ-------LRNLRDFLLVYNRMTELCFQRCVPSLHHRALDAEEEACLHSCAGKLIHSNHRLMAAYVQLMPALVQRRIADYE-------------AASAVPGVAAE-----------------------------QPGVSP------------SGS-------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q568N4-1", "uniprot_id": "T10B_DANRE", "id": "Q568N4-1", "name": "Mitochondrial import inner membrane translocase subunit Tim10 B", "aln": "MD----PQGQ-------LRNLRDFLLVYNRMTEICFHRCSSNFNYRNLTMDEERCVDSCAGKLIRTNHRLMGTYVQLMPAMVQKRMQEMESKAAEMAKAEAEAAAKAGTSVPDNPSSAITNASMMSPSIQDIPNTSSTAPNGFQILSSPDNTSDIKTSSMTNGSAFGETNLHVITNDAKTFTNQSLDELITPSPVNTSVPETPTAGGAGQTPS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9Y0V3-1", "uniprot_id": "T10B_DROME", "id": "Q9Y0V3-1", "name": "Mitochondrial import inner membrane translocase subunit Tim10B", "aln": "------MDSN-------LRNLKDFFTLYNKVTELCFSRCVDNLSQRDLGGHEDLCVDRCVTKFARFNQNMMKVYVDVQTTINAKRMEEMEEN-----------ARKAEQQQREQEKE--------------------------RLKEAA------------ATAVLTPVQPPVAGNLSM----------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "O74700-1", "uniprot_id": "TIM9_YEAST", "id": "O74700-1", "name": "Mitochondrial import inner membrane translocase subunit TIM9", "aln": "MDALNSKEQQEFQKVVEQKQMKDFMRLYSNLVERCFTDCVNDFTTSKLTNKEQTCIMKCSEKFLKHSERVGQRFQEQNAALGQG-LGR-----------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : ::::**: :*..:.* ** * .: * .*: *: * *: : ...: : . .:: : ", "identical_positions": 12, "similar_positions": 29, "identity": "5.63%" }, { "cls_id": "homologset.agr.MGI:1315197", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P04806-1", "uniprot_id": "HXKA_YEAST", "id": "P04806-1", "name": "Hexokinase-1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVHLGPKKPQARKGSMADVPKELMDEIHQLEDMFTVDSETLRKVVKHFIDELNKGLTKK---GGNIPMIPGWVMEFPTGKESGNYLAIDLGGTNLRVVLVKLSGNH--TFDTTQSKYKLPHDMRTTKHQEELWSFIADSLKDFMVEQELLNTKDTLPLGFTFSYPASQNKINEGILQRWTKGFDIPNVEGHDVVPLLQNEISKRE-LPIEIVALINDTVGTLIASYYTDPETKMGVIFGTGVNGAFYDVVSDIEKLEGKLADDIPSNSPMAINCEYGSF-DNEHLVLPRTKYDVAVDEQSPRPGQQAFEKMTSGYYLGELLRLVLLELNEKGLMLKDQDLSKLKQPYIMDTSYPARIEDDPFENLEDTDDIFQKDFGVKTTLPERKLIRRLCELIGTRAARLAVCGIAAICQKRGYKTG------HIAADGSVYNKYPGFKEAAAKGLRDIYGWTGDASKD-PITIVPAEDGSGAGAAVIAALSEKRIAEGKSLGIIGA-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P04807-1", "uniprot_id": "HXKB_YEAST", "id": "P04807-1", "name": "Hexokinase-2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVHLGPKKPQARKGSMADVPKELMQQIENFEKIFTVPTETLQAVTKHFISELEKGLSKK---GGNIPMIPGWVMDFPTGKESGDFLAIDLGGTNLRVVLVKLGGDR--TFDTTQSKYRLPDAMRTTQNPDELWEFIADSLKAFIDEQFPQGISEPIPLGFTFSFPASQNKINEGILQRWTKGFDIPNIENHDVVPMLQKQITKRN-IPIEVVALINDTTGTLVASYYTDPETKMGVIFGTGVNGAYYDVCSDIEKLQGKLSDDIPPSAPMAINCEYGSF-DNEHVVLPRTKYDITIDEESPRPGQQTFEKMSSGYYLGEILRLALMDMYKQGFIFKNQDLSKFDKPFVMDTSYPARIEEDPFENLEDTDDLFQNEFGINTTVQERKLIRRLSELIGARAARLSVCGIAAICQKRGYKTG------HIAADGSVYNRYPGFKEKAANALKDIYGWTQTSLDDYPIKIVPAEDGSGAGAAVIAALAQKRIAEGKSVGIIGA-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "O08528-1", "uniprot_id": "HXK2_MOUSE", "id": "O08528-1", "name": "Hexokinase-2", "aln": "MIASHMIACLFTELNQNQVQKVDQYLYHMRLSDETLLEISRRFRKEMEKGLGATTHPTAAVKMLPTFVRSTPDGTEHGEFLALDLGGTNFRVLRVRVTDNGLQRVEMENQIYAIPEDIMRGSGTQLFDHIAECLANFMDKLQIKEKKLPLGFTFSFPCHQTKLDESFLVSWTKGFKSSGVEGRDVVDLIRKAIQRRGDFDIDIVAVVNDTVGTMMTCGYDDQNCEIGLIVGTGSNACYMEEMRHIDMVEGDEGRMCINMEWGAFGDDGTLNDIRTEFDREIDMGSLNPGKQLFEKMISGMYMGELVRLILVKMAKAELLFQGKLSPELLTTGSFETKDVSDIEDDKDGIQKAYQILVRLGLSPLQEDCVATHRICQIVSTRSASLCAATLAAVLWRIKENKGEERLRSTIGVDGSVYKKHPHFAKRLHKAVRRLVPDCDVRFLRSEDGSGKGAAMVTAVAYRLADQHRARQKTLESLKLSHEQLLEVKRRMKVEMEQGLSKETHEAAPVKMLPTYVCATPDGTEKGDFLALDLGGTNFRVLLVRVRNGKRRGVEMHNKIYSIPQEVMHGTG-EELFDHIVQCIADFLEYMGMKGVS--LPLGFTFSFPCQQNSLDQSILLKWTKGFKASGCEGEDVVTLLKEAIRRREEFDLDVVAVVNDTVGTMMTCGYEDPHCEVGLIVGTGSNACYMEEMRNVELVDG-------EEGRMCVNMEWGAFGDNGCLDDLRTVFDVAVDELSLNPGKQRFEKMISGMYLGEIVRNILIDFTKRGLLFRGRISERLKTRGIFETKFLSQIESDCLALLQVR--AILRHLGLESTCDDSIIVKEVCTVVARRAAQLCGAGMAAVVDKIRENRGLDNLKVTVGVDGTLYKLHPHFAKVMHETVRDLA-------PKCDVSFLESEDGSGKGAALITAVACRIREAGQR-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P27881-1", "uniprot_id": "HXK2_RAT", "id": "P27881-1", "name": "Hexokinase-2", "aln": "MIASHMIACLFTELNQNQVQKVDQFLYHMRLSDETLLEISRRFRKEMEKGLGATTHPTAAVKMLPTFVRSTPDGTEHGEFLALDLGGTNFRVLRVRVTDNGLQRVEMENQIYAIPEDIMRGSGTQLFDHIAECLANFMDKLQIKEKKLPLGFTFSFPCHQTKLDESFLVSWTKGFKSSGVEGRDVVDLIRKAIQRRGDFDIDIVAVVNDTVGTMMTCGYDDQNCEIGLIVGTGSNACYMEEMRHIDMVEGDEGRMCINMEWGAFGDDGTLNDIRTEFDREIDMGSLNPGKQLFEKMISGMYMGELVRLILVKMAKAELLFQGKLSPELLTTGSFETKDVSDIEEDKDGIEKAYQILMRLGLNPLQEDCVATHRICQIVSTRSASLCAATLAAVLWRIKENKGEERLRSTIGVDGSVYKKHPHFAKRLHKAVRRLVPDCDVRFLRSEDGSGKGAAMVTAVAYRLADQHRARQKTLESLKLSHEQLLEVKRRMKVEMEQGLSKETHAVAPVKMLPTYVCATPDGTEKGDFLALDLGGTNFRVLLVRVRNGKRRGVEMHNKIYSIPQEVMHGTG-EELFDHIVQCIADFLEYMGMKGVS--LPLGFTFSFPCQQNSLDQSILLKWTKGFKASGCEGEDVVTLLKEAIHRREEFDLDVVAVVNDTVGTMMTCGYEDPHCEVGLIVGTGSNACYMEEMRNVELVDG-------EEGRMCVNMEWGAFGDNGCLDDLRTVFDVAVDELSLNPGKQRFEKMISGMYLGEIVRNILIDFTKRGLLFRGRISERLKTRGIFETKFLSQIESDCLALLQVR--AILRHLGLESTCDDSIIVKEVCTVVARRAAQLCGAGMAAVVDKIRENRGLDNLKVTVGVDGTLYKLHPHFAKVMHETVRDLA-------PKCDVSFLESEDGSGKGAALITAVACRIREAGQR-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P52789-1", "uniprot_id": "HXK2_HUMAN", "id": "P52789-1", "name": "Hexokinase-2", "aln": "MIASHLLAYFFTELNHDQVQKVDQYLYHMRLSDETLLEISKRFRKEMEKGLGATTHPTAAVKMLPTFVRSTPDGTEHGEFLALDLGGTNFRVLWVKVTDNGLQKVEMENQIYAIPEDIMRGSGTQLFDHIAECLANFMDKLQIKDKKLPLGFTFSFPCHQTKLDESFLVSWTKGFKSSGVEGRDVVALIRKAIQRRGDFDIDIVAVVNDTVGTMMTCGYDDHNCEIGLIVGTGSNACYMEEMRHIDMVEGDEGRMCINMEWGAFGDDGSLNDIRTEFDQEIDMGSLNPGKQLFEKMISGMYMGELVRLILVKMAKEELLFGGKLSPELLNTGRFETKDISDIEGEKDGIRKAREVLMRLGLDPTQEDCVATHRICQIVSTRSASLCAATLAAVLQRIKENKGEERLRSTIGVDGSVYKKHPHFAKRLHKTVRRLVPGCDVRFLRSEDGSGKGAAMVTAVAYRLADQHRARQKTLEHLQLSHDQLLEVKRRMKVEMERGLSKETHASAPVKMLPTYVCATPDGTEKGDFLALDLGGTNFRVLLVRVRNGKWGGVEMHNKIYAIPQEVMHGTG-DELFDHIVQCIADFLEYMGMKGVS--LPLGFTFSFPCQQNSLDESILLKWTKGFKASGCEGEDVVTLLKEAIHRREEFDLDVVAVVNDTVGTMMTCGFEDPHCEVGLIVGTGSNACYMEEMRNVELVEG-------EEGRMCVNMEWGAFGDNGCLDDFRTEFDVAVDELSLNPGKQRFEKMISGMYLGEIVRNILIDFTKRGLLFRGRISERLKTRGIFETKFLSQIESDCLALLQVR--AILQHLGLESTCDDSIIVKEVCTVVARRAAQLCGAGMAAVVDRIRENRGLDALKVTVGVDGTLYKLHPHFAKVMHETVKDLA-------PKCDVSFLQSEDGSGKGAALITAVACRIREAGQR-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9NFT7-1", "uniprot_id": "HXK2_DROME", "id": "Q9NFT7-1", "name": "Hexokinase-2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRKSTRLLTHSLFGPVFKILFHNKTVCGGCNRKMPSLVNTEIEAAVKGFLIDQEKMTEVVERMTKEIKMGLAKDTHARAVIKCFVSHVQDLPTGKERGKYLALDLGGSNFRVLLVNLISNS--DVETMSKGYNFPQTLMSGSG-KALFDFLAECLSEFCHSHGLENES--LALGFTFSFPLQQQGLSKGILVAWTKGFSCEGVVGKNVVSLLQEAIDRRGDLKINTVAILNDTVGTLMSCAFYHPNCRIGLIVGTGSNACYVEKTVNAECFEG---YQTSPKPSMIINCEWGAFGDNGVLEFVRTSYDKAVDKVTPNPGKQTFEKCISGMYMGELVRLVITDMIAKGFMFHGIISEKIQERWSFKTAYISDVESDAPGEYRNCNKVLSELGILGCQEPDKEALRYICEAVSSRSAKLCACGLVTIINKMN------INEVAIGIDGSVYRFHPKYHDMLQYHMKKLLK------PGVKFELVVSEDGSGRGAALVAATAVQAKSKL---------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9NFT9-1", "uniprot_id": "HXK1_DROME", "id": "Q9NFT9-1", "name": "Hexokinase-like protein", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MANTFNPEEDFPEVYKVCKLFNPSIDDLEKIKNAMDREITMGLSRDHHDRSTVPCHLSYVQDLPTGRERGQFLALEMMPTNCRIMLVKFSSER--DIYTSSKCVIMPHTVAAGRG-TEVFTFLATSIANFVKEKKVDKDN--LPLGIAFAFTLKKLALDVGILVSWTKEFGAQGAIGKDVVQLLRDALAKFPEISVDVMGIINVGAGSLLALCWAQPDTRIGLIMGSIANSCYVERVERCETYEG---DEYR--KLMIINSDWAHFGDTGQLDFIRNEYDRQLDTESINPGTRIYEKFSGALCMGELVRIIVLRLMKSGAIFAEDRRDYIGIQWKLDMVSLIEIVSDPPGVYTKAQEVMDKFRIRHCKERDLAALKYICDTVTNRAAMLVASGVSCLIDRMR------LPQISIAVDGGIYRLHPTFSTVLNKYTRLLAD------PNYNFEFVITQDSCGVGAAIMAGMAHANKYKTDAKLFTMDY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : : : : . : *: **::. . : * * * * *.:**::: :* *::**.. . . .. :*. : :: .:. .: * . :.**::*::. .: :. .** *** * . ..:** :*:. : : : :: :.::* .*:::: : .*. .:*:*.*: *..: : * :* * :* ::. * *. : *. :* :* : .** : :** .. :**::* : : * :: . : :. : .* : . : :: :. : *:* * .*: : :: :. ** :*. :* : : : . :: ::*..* ***:::. : ", "identical_positions": 66, "similar_positions": 147, "identity": "7.0%" }, { "cls_id": "homologset.agr.MGI:1315198", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q68FW2-1", "uniprot_id": "CDCA3_RAT", "id": "Q68FW2-1", "name": "Cell division cycle-associated protein 3", "aln": "MGSTQS---VSGTPARPL-----PRNKHVSRVADPRSPSAGIQRTPIQVESSPQPNPPA-EQLNSLKQAQDPDPRSPTLGIARTPMKISG-----------------PDSQCPLVKELSEVFETEVS-----------------ETEVSESISSPVLGLPQ---------------------------------------ETPLSSELDLPPDPDPQVSLEDQLLPWSQTELNSKQ----------VFAKEEAKQSTETMVSG----------------QTSDKPS--------------RDPETPQSSGSKRSRRKTN-NKVLGRSP--LTILQDDNSPGTLTLR--------------------QGKRPSALSENVK----------------DLKEGVILGTGR----FLKAGGGAWEQNEDHDK-----ENQHFALMES------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99M54-1", "uniprot_id": "CDCA3_MOUSE", "id": "Q99M54-1", "name": "Cell division cycle-associated protein 3", "aln": "MGSTQS---VSGTPARPL-----PRNKQVARVADPRSPSAGIQRTPIQVESSPQPSLPA-EQLNGLKQAQDPDPRSPTLGIARTPMKISG-----------------PDPQCSLVKELSEVLETEA----------------------SESISSPELALPR---------------------------------------ETPLFYDLDLSSDP--QLSPEDQLLPWSQAELDPKQ----------VFTKEEAKQSAETIAAS----------------QNSDKPS--------------RDPETPQSSGSKRSRRKAN-SKVLGRSP--LTILQDDNSPGTLTLR--------------------QGKRPSALSENVK----------------DLKEGVVLGTGR----FLKAGGGAREPNQDHDK-----ENQHFALLES------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99618-1", "uniprot_id": "CDCA3_HUMAN", "id": "Q99618-1", "name": "Cell division cycle-associated protein 3", "aln": "MGSAKS---VPVTPARPP-----PHNKHLARVADPRSPSAGILRTPIQVESSPQPGLPAGEQLEGLKHAQDSDPRSPTLGIARTPMKTSS-----------------GDPPSPLVKQLSEVFETED----------------------SKSNLPPEPVLPP---------------------------------------EAPLSSELDLPLGT--QLSVEEQMPPWNQTEFPSKQ----------VFSKEEARQPTETPVAS----------------QSSDKPS--------------RDPETPRSSGSMRNRWKPNSSKVLGRSP--LTILQDDNSPGTLTLR--------------------QGKRPSPLSENVS----------------ELKEGAILGTGR----LLKTGGRAWEQGQDHDK-----ENQHFPLVES------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1MT89-1", "uniprot_id": "Q1MT89_DANRE", "id": "Q1MT89-1", "name": "", "aln": "MGASESKMTVASTPKVTLDPSQRPKAARVAKLADPRSPSCAIDRTPIQVGVTYSP-LPVVESVG----PVFVDPRSPTPGITRTPMKVSVTSLARRLSTFFLSDIKSGDSPASPLPSVSFTKTSGMPGVAHPNTFGPKEPLLKAQSSHTDAISTPVLSSPSEGYGSICHSPFVLIGEPQMEVEVDTEASLEEAEEALLLGASPLRKELSLSLLACREGVYSSSLEERPLTPLPPADRQANEDHSYAVFTIPKSTENAESEATPSVVEAVLTLEEEEVPSQTSEEPASAALPEPIPEQPEENKPPTPQPADASSKPSPVSSTQVESVQPGIRCLRFDTRSPSQAIFKPQWLGVGFGASGVRARGVQSRGKTAVSSPRNIKNTATNENNNMVVRTKQKPREKVLIGEGRSPLQILRETNSPRERNLQMKLKVSTPERQRFSQMDRRALIMSLDKENE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:::* *. ** . *: :::::*******..* ****** : .* *. *.: . ****** **:***** * *. .. : .:* . : :.: .* * :** :*.*. . : ...: : : . : **: :: : :*: .: *.*::*: ..* **:.:.: . . .:* . .* : * .**. :: :** . . ..*:. . :* .::* ** :*: . . * . : . *.*:*. :: ", "identical_positions": 72, "similar_positions": 100, "identity": "15.82%" }, { "cls_id": "homologset.agr.MGI:1315199", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5M877-1", "uniprot_id": "SPSB2_RAT", "id": "Q5M877-1", "name": "SPRY domain-containing SOCS box protein 2", "aln": "MGQTALARGSSSTPSSHALYSDLSPPEGLEELLSAPPPDLGAQRHHGWNPKDCSENIDVKEGGLCFERRPVAQSTDGVRGKRGYSRGLHAWEISWPLEQRGTHAVVGVATALAPLQADHYAALLGSNSESWGWDIGRGKLYHQSKGLEAPQYPAGPQGEQLVVPERLLVVLDMEEGTLGYSIGGTYLGPAFRGLKGRTLYPSVSAVWGQCQVRIRYLGERRAEEPQSLLHLSRLCVRHALGDTRLGQISSLPLPPAMKRYLLYK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88838-1", "uniprot_id": "SPSB2_MOUSE", "id": "O88838-1", "name": "SPRY domain-containing SOCS box protein 2", "aln": "MGQTALARGSSSTPTSQALYSDFSPPEGLEELLSAPPPDLVAQRHHGWNPKDCSENIDVKEGGLCFERRPVAQSTDGVRGKRGYSRGLHAWEISWPLEQRGTHAVVGVATALAPLQADHYAALLGSNSESWGWDIGRGKLYHQSKGLEAPQYPAGPQGEQLVVPERLLVVLDMEEGTLGYSIGGTYLGPAFRGLKGRTLYPSVSAVWGQCQVRIRYMGERRVEEPQSLLHLSRLCVRHALGDTRLGQISTLPLPPAMKRYLLYK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99619-1", "uniprot_id": "SPSB2_HUMAN", "id": "Q99619-1", "name": "SPRY domain-containing SOCS box protein 2", "aln": "MGQTALAGGSSSTPTPQALYPDLSCPEGLEELLSAPPPDLGAQRRHGWNPKDCSENIEVKEGGLYFERRPVAQSTDGARGKRGYSRGLHAWEISWPLEQRGTHAVVGVATALAPLQTDHYAALLGSNSESWGWDIGRGKLYHQSKGPGAPQYPAGTQGEQLEVPERLLVVLDMEEGTLGYAIGGTYLGPAFRGLKGRTLYPAVSAVWGQCQVRIRYLGERRA-EPHSLLHLSRLCVRHNLGDTRLGQVSALPLPPAMKRYLLYQ", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******* ******:.:***.*:* *************** ***:************:****** ************.**************************************:***************************** *******.***** ******************:********************:**************:****. **:************ ********:*:*************:", "identical_positions": 237, "similar_positions": 18, "identity": "89.77%" }, { "cls_id": "homologset.agr.MGI:1315200", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z0E1-1", "uniprot_id": "M1AP_MOUSE", "id": "Q9Z0E1-1", "name": "Meiosis 1 arrest protein", "aln": "MNRRKTTSRGTSAAMKISHQPPRLLIVNIAVPSWVDICPNLCEALQNFFSIACSLMGPSRMSLFSLYTVQNQHECVLPFVQVRGNFIRLQACISELRMLQVEGCHRPPHALLPLAIEDGLQQFKQYSSHMASSAAQPWTSLEITVLTSRPGKEVVKELEEGLKDINLLSVRRLQVAEVTKGIQERSDSPSPTEEPSNDESSILEADIVLETLDNDVVSMEVFFKAWLHNSETDQENIHLLLTPQSLPPPSRAKDHPICLKCDLQERFLSPSLLPGTADGVSRIDDPKGDISTLYQMASLASASPYKLQVVKALKSSGICESLTYGLPFILRPTSCWQLDWDELETNQQHFHALCHCLLKRDWLLLARGEPLIHKHNQSLPACSFYVITPSHSLTLLVKLVATRELMLPGFFPLLSEDPPEDSLKIIESTLDSLDLGLTYNPLHVGSHLYSHLSSAHAKPQGRLYTSCASRGLRKG----GQLQTNRVRAAVVPLPVAPAPRRALKMTAASKASS-AAFLPSDSEEGEEERPSHT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZVK0-1", "uniprot_id": "D3ZVK0_RAT", "id": "D3ZVK0-1", "name": "", "aln": "MHRRRTTSRGTSPATKISHQPPRLLIVHIAVPSWDDICPNLCEALQNFFSIACSLMGPSRMSLFSLYTVQNQHECVLPFVQVRGNFVRLQACISELRTLQVEGCYRPSHTLLPLAVEDGLQQFKQYSSHMATSAAQPLTSLEITVLTSQPGKEVVKELEEGLKDINLLSVRRLQVVEVTKGIQEHTDSPSPIEEPSNDESSILEADIVLETLDNDVVSMEVFFKAWLHNTETDQENIHLFLTPQSLPPSSRAKDNPICLKCDLQERFLSPSLLPGTADSMSRIDDPKGDISTIYQMASLSSDSPYKLQVIKALKSSGICESLTYGLPFILRPTSCWQLDWDELETNQQHFHALCHCLMKRDWLLLARGEPLIPRHNQSLPACSFYVITPSHSLTLLVKLVATRELMLPGFFPLLSEDPPEDSLKIIESTLDSLELGLTYNPLQVGSHLYSHLSSAHAKPQGRPYTSWAGRGLRKG----DQLQTNRARAPVVPLPVTPVPGRALKKSAASKAAS-GTFLPSDSED---EYPSQT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8TC57-1", "uniprot_id": "M1AP_HUMAN", "id": "Q8TC57-1", "name": "Meiosis 1 arrest protein", "aln": "MHPGRTTGKGPSTHTQIDQQPPRLLIVHIALPSWADICTNLCEALQNFFSLACSLMGPSRMSLFSLYMVQDQHECILPFVQVKGNFARLQTCISELRMLQREGCFRSQGASLRLAVEDGLQQFKQYSRHVTTRAALTYTSLEITILTSQPGKEVVKQLEEGLKDTDLARVRRFQVVEVTKGILEHVDSASPVEDTSNDESSILGTDIDLQTIDNDIVSMEIFFKAWLHNSGTDQEQIHLLLSSQCFSNISRPRDNPMCLKCDLQERLLCPSLLAGTADGSLRMDDPKGDFITLYQMASQSSASHYKLQVIKALKSSGLCESLTYGLPFILRPTSCWQLDWDELETNQQHFHALCHSLLKREWLLLAKGEPPGPGHSQRIPASTFYVIMPSHSLTLLVKAVATRELMLPSTFPLLPEDPHDDSLKNVESMLDSLELEPTYNPLHVQSHLYSHLSSIYAKPQGRLHPHWESRAPRKHPCKTGQLQTNRARATVAPLPMTPVPGRASKMPAASKSSSDAFFLPSEWEK----DPSRP", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: :**.:*.*. :*.:********:**:*** ***.***********:**************** **:****:******:*** ***:****** ** ***.*. : * **:*********** *::: ** . ******:***:*******:******* :* ***:**.****** *: **.** *:.******** :** *:*:***:****:********: ****:***:*:.*.:. **.:*:*:*********:*.****.****. *:******: *:***** :* * *****:*******:*************************************.*:**:*****:*** *.* :**.:**** ********** *********. ****.*** :**** :** ****:* *****:* ********* :****** :. .*. ** .******.**.*.***::*.* ** * .****::* . ****: *. **:.", "identical_positions": 368, "similar_positions": 96, "identity": "68.91%" }, { "cls_id": "homologset.agr.MGI:1315201", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99622-1", "uniprot_id": "C10_HUMAN", "id": "Q99622-1", "name": "Protein C10", "aln": "MASASTQPAALSAEQAKVVLAEVIQAFSAPENAVRMDEARDNACNDMGKMLQFVLPVATQIQQEVIKAYGFSCDGEGVLKFARLVKSYEAQDPEIASLSGKLKALFLPPMTLPPHGPAAGGSVAAS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O35127-1", "uniprot_id": "C10_MOUSE", "id": "O35127-1", "name": "Protein C10", "aln": "MASASAQPAALSAEQAKVVLAEVIQAFSAPENAVRMDEARDNACNDMGKMLQFVLPVATQIQQEVIKAYGFSCDGEGVLKFARLVKSYEAQDPEIASLSGKLKALFLPPMTLPPHGPASGSSVAAS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6TH01-1", "uniprot_id": "C10_DANRE", "id": "Q6TH01-1", "name": "Protein C10", "aln": "MASAPAQQPTLTVEQARVVLSEVIQAFSVPENAARMEEARESACNDMGKMLQLVLPVATQIQQEVIKAYGFNNEGEGVLKFARLVKMYETQDPEIAAMSVKLKSLLLPPLSTPPIG--SG--IPTS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A8DYT6-1", "uniprot_id": "A8DYT6_DROME", "id": "A8DYT6-1", "name": "Protein C10", "aln": "----MSYLTNFNSDTAKQILMDIIRCVNQPENSKKLSEAKASAGKEMILMMQHVFPLVMQLQLEVIKGHGFPGNREGLVQFSQLIREMERDDMEIVRLRSQIRAIYLPPIAINTTNDILI------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . :. : *: :* ::*:... ***: ::.**: .* ::* *:* *:*:. *:* ****.:** : **:::*::*:: * :* **. : ::::: ***:: . . ", "identical_positions": 33, "similar_positions": 48, "identity": "26.19%" }, { "cls_id": "homologset.agr.MGI:1315202", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88280-1", "uniprot_id": "SLIT3_RAT", "id": "O88280-1", "name": "Slit homolog 3 protein", "aln": "MAPGRTGAGAAVRARLALALALASILSGP---------------------------------------PAAACPTKCTCSAASVDCHGLGLRAVPRGIPRNAERLDLDRNNITRITKMDFTGLKNLRVLHLEDNQVSVIERGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKAFRGVTGVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVTSFNHMPKIRTLRLHSNHLYCDCHLAWLSDWLRQRRTIGQFTLCMAPVHLRGFSVADVQKKEYVCPGPHSEAP-ACNANSLSCPSACSCSNNIVDCRGKGLTEIPANLPEGIVEIRLEQNSIKSIPAGAFIQYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIPKGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQNPFVCDCHLKWLADYLQDNPIETSGARCSSPRRLANKRISQIKSKKFRCSGSEDYRNRFSSECFMDLVCPEKCRCEGTIVDCSNQKLSRIPSHLPEYTTDLRLNDNDIAVLEATGIFKKLPNLRKINLSNNRIKEVREGAFDGAAGVQELMLTGNQLETMHGRMFRGLSGLKTLMLRSNLISCVNNDTFAGLSSVRLLSLYDNRITTISPGAFTTLVSLSTINLLSNPFNCNCHMAWLGRWLRKRRIVSGNPRCQKPFFLKEIPIQDVAIQDFTCEGNEENSCQLS-PRCPEQCTCVETVVRCSNRGLHTLPKGMPKDVTELYLEGNHLTAVP-KELSTFRQLTLIDLSNNSISMLTNHTFSNMSHLSTLILSYNRLRCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGINPLHCDCSLRWLSEWIKAGYKEPGIARCSSPESMADRLLLTTPTHRFQCK----------GPVDINIVAKCNACLSSPCKNNGTCSQDPVEQYRCTCPYSYKGKDCTVPINTCVQNPCQHGGTCHLSESHRDGFSCSCPLGFEGQRCEINPDDCE-DNDCENSATCVDGINNYACVCPPNYTGELCDEVIDYCVPEMNLCQHEAKCISLDKGFRCECVPGYSGKLCETDNDDCVAHKCRHGAQCVDAVNGYTCICPQGFSGLFCEHPPPMVLLQ--TSPCDQYECQNGAQCIVVQQ--EPTCRCPPGFAGPRCEKLITVNFVGKDSYVELASAKVRPQANISLQVATDKDNGILLYKGDNDPLALELYQGHVRLVYDSLSSPPTTVYSVETVNDGQFHSVELVMLNQTLNLVVDKGAPKSLGKLQKQPAVGINSPLYLGGIPTSTGLSALRQGADRPLGGFHGCIHEVRINNELQDFKALPPQSLGVSPGCKSCTVCRHGLCRSVEKDSVVCECHPGWTGPLCDQEAQ-DPCLGHSCSHG-TCVATGNS---YVCKCAEGYEGPLCDQKNDSANACSAFKCHHGQCHISDRGEPYCLCQPGFSGNHCEQENPCLGEIVREAIRRQKDYASCATASKVPIMVCRGGCGS-QCCQPIRSKRRKYVFQCTDGSSFVEEVERHLECGCRECS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WVB4-1", "uniprot_id": "SLIT3_MOUSE", "id": "Q9WVB4-1", "name": "Slit homolog 3 protein", "aln": "MALGRTGAGAAVRARLALGLALASILSGP---------------------------------------PAAACPTKCTCSAASVDCHGLGLRAVPRGIPRNAERLDLDRNNITRITKMDFAGLKNLRVLHLEDNQVSIIERGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKAFRGVTGVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVTSFNHMPKIRTLRLHSNHLYCDCHLAWLSDWLRQRRTIGQFTLCMAPVHLRGFSVADVQKKEYVCPGPHSEAP-ACNANSLSCPSACSCSNNIVDCRGKGLTEIPANLPEGIVEIRLEQNSIKSIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIPKGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFVPLQSIQTLHLAQNPFVCDCHLKWLADYLQDNPIETSGARCSSPRRLANKRISQIKSKKFRCSGSEDYRNRFSSECFMDLVCPEKCRCEGTIVDCSNQKLARIPSHLPEYTTDLRLNDNDISVLEATGIFKKLPNLRKINLSNNRIKEVREGAFDGAAGVQELMLTGNQLETMHGRMFRGLSSLKTLMLRSNLISCVSNDTFAGLSSVRLLSLYDNRITTITPGAFTTLVSLSTINLLSNPFNCNCHMAWLGRWLRKRRIVSGNPRCQKPFFLKEIPIQDVAIQDFTCDGNEESSCQLS-PRCPEQCTCVETVVRCSNRGLHALPKGMPKDVTELYLEGNHLTAVP-KELSAFRQLTLIDLSNNSISMLTNHTFSNMSHLSTLILSYNRLRCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGTNPLHCDCSLRWLSEWVKAGYKEPGIARCSSPESMADRLLLTTPTHRFQCK----------GPVDINIVAKCNACLSSPCKNNGTCSQDPVEQYRCTCPYSYKGKDCTVPINTCVQNPCEHGGTCHLSENLRDGFSCSCPLGFEGQRCEINPDDCE-DNDCENSATCVDGINNYACLCPPNYTGELCDEVIDYCVPEMNLCQHEAKCISLDKGFRCECVPGYSGKLCETNNDDCVAHKCRHGAQCVDEVNGYTCICPQGFSGLFCEHPPPMVLLQ--TSPCDQYECQNGAQCIVVQQ--EPTCRCPPGFAGPRCEKLITVNFVGKDSYVELASAKVRPQANISLQVATDKDNGILLYKGDNDPLALELYQGHVRLVYDSLSSPPTTVYSVETVNDGQFHSVELVMLNQTLNLVVDKGAPKSLGKLQKQPAVGSNSPLYLGGIPTSTGLSALRQGADRPLGGFHGCIHEVRINNELQDFKALPPQSLGVSPGCKSCTVCRHGLCRSVEKDSVVCECHPGWTGPLCDQEAR-DPCLGHSCRHG-TCMATGDS---YVCKCAEGYGGALCDQKNDSASACSAFKCHHGQCHISDRGEPYCLCQPGFSGHHCEQENPCMGEIVREAIRRQKDYASCATASKVPIMECRGGCGS-QCCQPIRSKRRKYVFQCTDGSSFVEEVERHLECGCRACS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75094-1", "uniprot_id": "SLIT3_HUMAN", "id": "O75094-1", "name": "Slit homolog 3 protein", "aln": "MAPGWAGVGAAVRARLALALALASVLSGP---------------------------------------PAVACPTKCTCSAASVDCHGLGLRAVPRGIPRNAERLDLDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVTSFNHMPKIRTLRLHSNHLYCDCHLAWLSDWLRQRRTVGQFTLCMAPVHLRGFNVADVQKKEYVCPAPHSEPP-SCNANSISCPSPCTCSNNIVDCRGKGLMEIPANLPEGIVEIRLEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIVKGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQNPFVCDCHLKWLADYLQDNPIETSGARCSSPRRLANKRISQIKSKKFRCSGSEDYRSRFSSECFMDLVCPEKCRCEGTIVDCSNQKLVRIPSHLPEYVTDLRLNDNEVSVLEATGIFKKLPNLRKINLSNNKIKEVREGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLMLRSNLIGCVSNDTFAGLSSVRLLSLYDNRITTITPGAFTTLVSLSTINLLSNPFNCNCHLAWLGKWLRKRRIVSGNPRCQKPFFLKEIPIQDVAIQDFTCDGNEESSCQLS-PRCPEQCTCMETVVRCSNKGLRALPRGMPKDVTELYLEGNHLTAVP-RELSALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLILSYNRLRCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGTNPLHCDCSLRWLSEWVKAGYKEPGIARCSSPEPMADRLLLTTPTHRFQCK----------GPVDINIVAKCNACLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSHKDGFSCSCPLGFEGQRCEINPDDCE-DNDCENNATCVDGINNYVCICPPNYTGELCDEVIDHCVPELNLCQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCVAHKCRHGAQCVDTINGYTCTCPQGFSGPFCEHPPPMVLLQ--TSPCDQYECQNGAQCIVVQQ--EPTCRCPPGFAGPRCEKLITVNFVGKDSYVELASAKVRPQANISLQVATDKDNGILLYKGDNDPLALELYQGHVRLVYDSLSSPPTTVYSVETVNDGQFHSVELVTLNQTLNLVVDKGTPKSLGKLQKQPAVGINSPLYLGGIPTSTGLSALRQGTDRPLGGFHGCIHEVRINNELQDFKALPPQSLGVSPGCKSCTVCKHGLCRSVEKDSVVCECRPGWTGPLCDQEAR-DPCLGHRCHHG-KCVATGTS---YMCKCAEGYGGDLCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQQENPCLGQVVREVIRRQKGYASCATASKVPIMECRGGCGP-QCCQPTRSKRRKYVFQCTDGSSFVEEVERHLECGCLACS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58H752-1", "uniprot_id": "A0AC58H752_DANRE", "id": "A0AC58H752-1", "name": "", "aln": "---------MMRWVKYWGTVAVLCGLLSC---------------------------------------AVNGCPHKCSCSGSHVDCQGQAFKTVPRGIPRNAERLDLDRNNITRITKVDFSGLKNLRVLHLENNQISVIERGAFEGLKQLERIRLNRNRLQVLPELLFQSTTKLSRLDLSENQIQAVPRKAFRGITTVKNLQLDSNHISCIEDGAFRALRDLEILTLNNNNITLIPLSSFNHMPKLRTLRLHSNNLHCDCHLSWLSDWLRQRRGLAPFTQCMAPAHMRGLNVPDVQKREFVCTGPVETEPRSCAPQVTICPAACTCNNNIVDCRRKGLTEIPANLPEGIVEIRLEQNMIKNIPAGAFSTYKKLKRIDLSKNQISEIAEDAFSGLRSLTSLVLYGNKIAEIPKGLFDGLVSLQLLLLNANKINCLRVNTFKDLQNLNLLSLYDNKLQTISKGLFAPLRAIKTLHLAQNPFMCDCHLKWLADYLFDNPIETSGARCSHPRRLANKRISQVKGKKFRCTGAEDYRSRLSGECFQDLVCPERCRCEGTVVDCSNLKLTKIPPHLPEHTTDLRLNDNEISILEATGAFKKLPNLRKINLSNNKLRDIREGAFDGAGGVLELLLTGNKLQSVSGRMFKGLIGLKTLMLRSNQISCVDNATFTGLSSVRLLSLYDNRISTIAPGAFNTLHSLSTINLLSNPYVCDCHLAWLGLWLKKTRVVSGNPRCQKPAFLKEIPIQDVAMPDFSCDGAEENVCLPSAPRCPESCTCSETVVRCSNRGLRSLPKTIPKDTTELYLEGNLLTSVP-KELPNLKQLTLLDLSNNSISHLAPLTFSNMTQLATLILSYNQIRCVPVHAFDGLRSLRLLTLHGNDLSTVPEGAFNHLTSLSHLALGANPLYCDCELRWLSQWVKAGFKEPGIARCTGPPDMADRLLLTTPLNRFQCKDAALEMPHTSGPADLNLMSKCAPCLATPCQNNGTCVSDVTGSYHCTCPFGYKGRNCEIPINACISLPCTNGGTCHLTPGLDGQYSCVCPPGYEGQQCELNPDDCE-DNDCENNSTCVDGINNYTCVCPPNYKGDLCEEVVDPCLPGFDLCQHDSKCVPLSKGYRCECLPGYVGQQCEQDYNDCLENKCQHGAECVDAINGYTCVCKEGFSGLFCENHPPMVLLQN-TSPCDQSDCQNGSECLVMEG--EPVCRCLPGYFGTKCQKMVTLHFLGKEAYVELSGTRIRPPMHISFQVATDKDNGILLYKEDHDPLALELYQGHIRLIYDISKYPPTTVYSVESVNDGLFHTVEVLIQNQTLSLVVDKGTPKSLGKLPRPPAVDHNTQLYIGGVPSLIGTSGLRPG---PFQSFNGCLHDVRLNGELQDLGAGLAGIEGVLFGCHSCSVCDQGACRQRGDEGVTCDCPTGHSGPLCEQMSSQDPCESSRCVHG-ECVAKGSS---YSCLCVDGYSGQFCDRQDESS-ACKGLHCVYGECRLTESGEPACHCQPGYSGPTCETELTCEGEAVRDYLYRQMAHKICTSTSRVQRLECRHSCSSGLCCAPTKSRRRKLSFKCPDGSSFSEEMEITVECGCTKCSS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P24014-1", "uniprot_id": "SLIT_DROME", "id": "P24014-1", "name": "Protein slit", "aln": "MAAPSRTTLMPPPFRLQLRLLILPILLLLRHDAVHAEPYSGGFGSSAVSSGGLGSVGIHIPGGGVGVITEARCPRVCSCTGLNVDCSHRGLTSVPRKISADVERLELQGNNLTVIYETDFQRLTKLRMLQLTDNQIHTIERNSFQDLVSLERLRLNNNRLKAIPENFVTSSASLLRLDISNNVITTVGRRVFKGAQSLRSLQLDNNQITCLDEHAFKGLVELEILTLNNNNLTSLPHNIFGGLGRLRALRLSDNPFACDCHLSWLSRFLRSATRLAPYTRCQSPSQLKGQNVADLHDQEFKCSGLTEHAPMECGAEN-SCPHPCRCADGIVDCREKSLTSVPVTLPDDTTELRLEQNFITELPPKSFSSFRRLRRIDLSNNNISRIAHDALSGLKQLTTLVLYGNKIKDLPSGVFKGLGSLQLLLLNANEISCIRKDAFRDLHSLSLLSLYDNNIQSLANGTFDAMKSIKTVHLAKNPFICDCNLRWLADYLHKNPIETSGARCESPKRMHRRRIESLREEKFKCS-WDELRMKLSGECRMDSDCPAMCHCEGTTVDCTGRGLKEIPRDIPLHTTELLLNDNELGRISSDGLFGRLPHLVKLELKRNQLTGIEPNAFEGASHIQELQLGENKIKEISNKMFLGLHQLKT------------------------LNLYDNQISCVMPGSFEHLNSLTSLNLASNPFNCNCHLAWFAEWLRKKSLNGGAARCGAPSKVRDVQIKDLPHSEFKCSSENSEGCLGD-GYCPPSCTCTGTVVRCSRNQLKEIPRGIPAETSELYLESNEIEQIHYERIRHLRSLTRLDLSNNQITILSNYTFANLTKLSTLIISYNKLQCLQRHALSGLNNLRVLSLHGNRISMLPEGSFEDLKSLTHIALGSNPLYCDCGLKWFSDWIKLDYVEPGIARCAEPEQMKDKLILSTPSSSFVCR----------GRVRNDILAKCNACFEQPCQNQAQCVALPQREYQCLCQPGYHGKHCEFMIDACYGNPCRNNATCTVLE--EGRFSCQCAPGYTGARCETNIDDCLGEIKCQNNATCIDGVESYKCECQPGFSGEFCDTKIQFCSPEFNPCANGAKCMDHFTHYSCDCQAGFHGTNCTDNIDDCQNHMCQNGGTCVDGINDYQCRCPDDYTGKYCEGHNMISMMYPQTSPCQNHECKHGVCFQPNAQGSDYLCRCHPGYTGKWCEYLTSISFVHNNSFVELEPLRTRPEANVTIVFSSAEQNGILMYDGQDAHLAVELFNGRIRVSYDVGNHPVSTMYSFEMVADGKYHAVELLAIKKNFTLRVDRGLARSIINEGSNDYLKLTTPMFLGGLPVDPAQQAYKNWQIRNLTSFKGCMKEVWINHKLVDFGNAQRQQK-ITPGCALLEGEQQ---EEEDDEQDFMDETP------HIKEEPVDPCLENKCRRGSRCVPNSNARDGYQCKCKHGQRGRYCDQGEGST-------------------------EP----PTVTAASTCRKEQVREYYTEN----DCRSRQPLKYAKCVGGCGN-QCCAAKIVRRRKVRMVCSNNRKYIKNLDIVRKCGCTKKCY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 542, "similar_positions": 480, "identity": "34.15%" }, { "cls_id": "homologset.agr.MGI:1315203", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88279-1", "uniprot_id": "SLIT1_RAT", "id": "O88279-1", "name": "Slit homolog 1 protein", "aln": "MALTPQRGSSSGLSRPELWLLLWAAAWRLG---------------------------------------ATACPALCTCTGTTVDCHGTGLQAIPKNIPRNTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLQVLPELLFQNNQALSRLDLSENSLQAVPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHLFCDCHLAWLSQWLRQRPTIGLFTQCSGPASLRGLNVAEVQKSEFSCSGQGEAAQVPACTLSSGSCPAMCSCSNGIVDCRGKGLTAIPANLPETMTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQNPFICDCNLKWLADFLRTNPIETTGARCASPRRLANKRIGQIKSKKFRCSAKEQYFIPGTEDYHLNSECTSDVACPHKCRCEASVVECSGLKLSKIPERIPQSTTELRLNNNEISILEATGLFKKLSHLKKINLSNNKVSEIEDGTFEGATSVSELHLTANQLESVRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNHITTISPGAFDTLQALSTLNLLANPFNCNCQLAWLGDWLRKRKIVTGNPRCQNPDFLRQIPLQDVAFPDFRCEEGQEEVGCLPRPQCPQECACLDTVVRCSNKHLQALPKGIPKNVTELYLDGNQFTLVP-GQLSTFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNALQCIPPLAFQGLRSLRLLSLHGNDVSTLQEGIFADVTSLSHLAIGANPLYCDCHLRWLSSWVKTGYKEPGIARCAGPPEMEGKLLLTTPAKKFECQGPPSLAVQAKCDPCLSSPCQNQGTCHNDPLEVYRCTCPSGYKGRNCEVSLDSCSSNPCGNGGTCHAQEGEDAGFTCSCPSGFEGLTCGMNTDDCV-KHDCVNGGVCVDGIGNYTCQCPLQYTGRACEQLVDFCSPDLNPCQHEAQCVGTPEGPRCECVPGYTGDNCSKNQDDCKDHQCQNGAQCVDEINSYACLCAEGYSGQLCEIP------PAPRNSCEGTECQNGANCVD--QGSRPVCQCLPGFGGPECEKLLSVNFVDRDTYLQFTDLQNWPRANITLQVSTAEDNGILLYNGDNDHIAVELYQGHVRVSYDPGSYPSSAIYSAETINDGQFHTVELVTFDQMVNLSIDGGSPMTMDNFGKHYTLNSEAPLYVGGMPVDVNSAAFRLWQILNGTSFHGCIRNLYINNELQDFTKTQMKPGVVPGCEPCRKLYCLHGICQPNATPGPVCHCEAGWGGLHCDQPVDGPCHGHKCVHG-KCVP--LDALAYSCQCQDGYSGALCNQVGAVAEPCGGLQCLHGHCQASATRGAHCVCSPGFSGELCEQESECRGDPVRDFHRVQRGYAICQTTRPLSWVECRGACPGQGCCQGLRLKRRKLTFECSDGTSFAEEVEKPTKCGCAPCA-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80TR4-1", "uniprot_id": "SLIT1_MOUSE", "id": "Q80TR4-1", "name": "Slit homolog 1 protein", "aln": "MALTPQRGSSSGLSRPELWLLLWAAAWRLG---------------------------------------ATACPALCTCTGTTVDCHGTGLQAIPKNIPRNTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLQVLPELLFQNNQALSRLDLSENFLQAVPRKAFRGATDLKNLQLDKNRISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHLFCDCHLAWLSQWLRQRPTIGLFTQCSGPASLRGLNVAEVQKGEFSCSGQGEAAGAPACTLSSGSCPAMCSCSSGIVDCRGKGLTAIPANLPETMTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQNPFICDCNLKWLADFLRTNPIETTGARCASPRRLANKRIGQIKSKKFRCSAKEQYFIPGTEDYHLNSECTSDVACPHKCRCEASVVECSSLKLSKIPERIPQSTTELRLNNNEISILEATGLFKKLSHLKKINLSNNKVSEIEDGTFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNHITTISPGAFDTLQALSTLNLLANPFNCNCHLSWLGDWLRKRKIVTGNPRCQNPDFLRQIPLQDVAFPDFRCEEGQEEVGCLPRPQCPQECACLDTVVRCSNKHLQALPKGIPKNVTELYLDGNQFTLVP-GQLSTFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNALQCIPPLAFQGLRSLRLLSLHGNDVSTLQEGIFADVTSLSHLAIGANPLYCDCRLRWLSSWVKTGYKEPGIARCAGPPEMEGKLLLTTPAKKFECQGPPSLAVQAKCDPCLSSPCQNQGTCHNDPLEVYRCTCPSGYKGRHCEVSLDGCSSNPCGNGGTCHAQEGEDAGFTCSCPSGFEGPTCGVDTDDCV-KHACVNGGVCVDGVGNYTCQCPLQYTGRACEQLVDFCSPDMNPCQHEAQCVGTPDGPRCECMLGYTGDNCSENQDDCKDHKCQNGAQCVDEVNSYACLCVEGYSGQLCEIP------PAPRSSCEGTECQNGANCVD--QGSRPVCQCLPGFGGPECEKLLSVNFVDRDTYLQFTDLQNWPRANITLQVSTAEDNGILLYNGDNDHIAVELYQGHVRVSYDPGSYPSSAIYSAETINDGQFHTVELVTFDQMVNLSIDGGSPMTMDNFGKHYTLNSEAPLYVGGMPVDVNSAAFRLWQILNGTSFHGCIRNLYINNELQDFTKTQMKPGVVPGCEPCRKLYCLHGICQPNATPGPVCHCEAGWGGLHCDQPVDGPCHGHKCVHG-KCVP--LDALAYSCQCQDGYSGALCNQVGAVAEPCGGLQCLHGHCQASATKGAHCVCSPGFSGELCEQESECRGDPVRDFHRVQRGYAICQTTRPLSWVECRGACPGQGCCQGLRLKRRKLTFECSDGTSFAEEVEKPTKCGCAQCA-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75093-1", "uniprot_id": "SLIT1_HUMAN", "id": "O75093-1", "name": "Slit homolog 1 protein", "aln": "MALTPGWGSSAGPVRPELWLLLWAAAWRLG---------------------------------------ASACPALCTCTGTTVDCHGTGLQAIPKNIPRNTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHLFCDCHLAWLSQWLRQRPTIGLFTQCSGPASLRGLNVAEVQKSEFSCSGQGEAGRVPTCTLSSGSCPAMCTCSNGIVDCRGKGLTAIPANLPETMTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQNPFICDCNLKWLADFLRTNPIETSGARCASPRRLANKRIGQIKSKKFRCSAKEQYFIPGTEDYQLNSECNSDVVCPHKCRCEANVVECSSLKLTKIPERIPQSTAELRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLANPFNCNCQLAWLGGWLRKRKIVTGNPRCQNPDFLRQIPLQDVAFPDFRCEEGQEEGGCLPRPQCPQECACLDTVVRCSNKHLRALPKGIPKNVTELYLDGNQFTLVP-GQLSTFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNALQCIPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHLAIGANPLYCDCHLRWLSSWVKTGYKEPGIARCAGPQDMEGKLLLTTPAKKFECQGPPTLAVQAKCDLCLSSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQEGEDAPFTCSCPTGFEGPTCGVNTDDCV-DHACANGGVCVDGVGNYTCQCPLQYEGKACEQLVDLCSPDLNPCQHEAQCVGTPDGPRCECMPGYAGDNCSENQDDCRDHRCQNGAQCMDEVNSYSCLCAEGYSGQLCEIPPHL---PAPKSPCEGTECQNGANCVD--QGNRPVCQCLPGFGGPECEKLLSVNFVDRDTYLQFTDLQNWPRANITLQVSTAEDNGILLYNGDNDHIAVELYQGHVRVSYDPGSYPSSAIYSAETINDGQFHTVELVAFDQMVNLSIDGGSPMTMDNFGKHYTLNSEAPLYVGGMPVDVNSAAFRLWQILNGTGFHGCIRNLYINNELQDFTKTQMKPGVVPGCEPCRKLYCLHGICQPNATPGPMCHCEAGWVGLHCDQPADGPCHGHKCVHG-QCVP--LDALSYSCQCQDGYSGALCNQAGALAEPCRGLQCLHGHCQASGTKGAHCVCDPGFSGELCEQESECRGDPVRDFHQVQRGYAICQTTRPLSWVECRGSCPGQGCCQGLRLKRRKFTFECSDGTSFAEEVEKPTKCGCALCA-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P24014-1", "uniprot_id": "SLIT_DROME", "id": "P24014-1", "name": "Protein slit", "aln": "MAAPSRTTLMPPPFRLQLRLLILPILLLLRHDAVHAEPYSGGFGSSAVSSGGLGSVGIHIPGGGVGVITEARCPRVCSCTGLNVDCSHRGLTSVPRKISADVERLELQGNNLTVIYETDFQRLTKLRMLQLTDNQIHTIERNSFQDLVSLERLRLNNNRLKAIPENFVTSSASLLRLDISNNVITTVGRRVFKGAQSLRSLQLDNNQITCLDEHAFKGLVELEILTLNNNNLTSLPHNIFGGLGRLRALRLSDNPFACDCHLSWLSRFLRSATRLAPYTRCQSPSQLKGQNVADLHDQEFKCSGLTEHAPMECG--AENSCPHPCRCADGIVDCREKSLTSVPVTLPDDTTELRLEQNFITELPPKSFSSFRRLRRIDLSNNNISRIAHDALSGLKQLTTLVLYGNKIKDLPSGVFKGLGSLQLLLLNANEISCIRKDAFRDLHSLSLLSLYDNNIQSLANGTFDAMKSIKTVHLAKNPFICDCNLRWLADYLHKNPIETSGARCESPKRMHRRRIESLREEKFKCSWDELRMK-------LSGECRMDSDCPAMCHCEGTTVDCTGRGLKEIPRDIPLHTTELLLNDNELGRISSDGLFGRLPHLVKLELKRNQLTGIEPNAFEGASHIQELQLGENKIKEISNKMFLGLHQLKT------------------------LNLYDNQISCVMPGSFEHLNSLTSLNLASNPFNCNCHLAWFAEWLRKKSLNGGAARCGAPSKVRDVQIKDLPHSEFKCSSENSE-GCLGDGYCPPSCTCTGTVVRCSRNQLKEIPRGIPAETSELYLESNEIEQIHYERIRHLRSLTRLDLSNNQITILSNYTFANLTKLSTLIISYNKLQCLQRHALSGLNNLRVLSLHGNRISMLPEGSFEDLKSLTHIALGSNPLYCDCGLKWFSDWIKLDYVEPGIARCAEPEQMKDKLILSTPSSSFVCRGRVRNDILAKCNACFEQPCQNQAQCVALPQREYQCLCQPGYHGKHCEFMIDACYGNPCRNNATCTVLE--EGRFSCQCAPGYTGARCETNIDDCLGEIKCQNNATCIDGVESYKCECQPGFSGEFCDTKIQFCSPEFNPCANGAKCMDHFTHYSCDCQAGFHGTNCTDNIDDCQNHMCQNGGTCVDGINDYQCRCPDDYTGKYCEGHNMISMMYPQTSPCQNHECKHGVCFQPNAQGSDYLCRCHPGYTGKWCEYLTSISFVHNNSFVELEPLRTRPEANVTIVFSSAEQNGILMYDGQDAHLAVELFNGRIRVSYDVGNHPVSTMYSFEMVADGKYHAVELLAIKKNFTLRVDRGLARSIINEGSNDYLKLTTPMFLGGLPVDPAQQAYKNWQIRNLTSFKGCMKEVWINHKLVDFGNAQRQQKITPGCA------LLEGEQQEEEDDEQDFMDET----PHIKEEPVDPCLENKCRRGSRCVPNSNARDGYQCKCKHGQRGRYCDQGEGSTEPP-----------------------------TVTAASTCRKEQVREYYTEND----CRSRQPLKYAKCVGGC-GNQCCAAKIVRRRKVRMVCSNNRKYIKNLDIVRKCGCTKKCY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** .. . * :* **: . * : ** :*:*** .*** ** ::*::*. :.*****:***:* *::.** *.:**:*** :*** ::**.:*:*: .*******.*:*: :** :. .. :* ***:*:* : :: *:.*:** .*:.****:*:*:*::* **:.* **:*******:*::* . *. : :**::** .* : *****:***::**. . :. :*:*..*:.*:* ***:::. **.*** * . :..*** * *:.****** *.**::*..**: **:*** * *..:** :**.:*:*********:*:.** **:.**:.*.:********.*** *** ** :*********:*.*** ***:**:.*********:*****:*** ::::*:*:***:*********:****:*:.*****:**** **:*: .:** .::.:**:** .* : *..** * ** *:**...*:*:. *.:**. ** *:** **:**:. :.: *:* :*.** *::*..*::: ** .:****: :.**:* *:::.: . ** **. *:* *.****:*: : **:*: *::*::*** :*******:*:*:. ****:.: * .** *. :*:: ::*:...:*:*.. :.* *** ** .*:* .******.::*: :*:*** :.:****:.*:: : :: :: * :*****:*: *** :*:*:::*:***:*** ***: *:.**..**:****** :* * ** * *:.**:*:*:*:******* *:*:*.*:* .* ******** * :*:.**:*:**:..* *:* : ***: *:..*****. * * . *:* * .**:*:.**. :*.* ..** *..** . * :. *:*.*..*: * * : ***: . * *...*:**: .*.*:* : *. *: :::***::*** : *:*:. *:* *: * **:.* ***::* ****. *:* :*.* * * :.*:*: ** . ..*:. **::*. **. :*:* **: * ** * *:.**..:::::: *:. *.**:*: .*:**:****:*:*:: *:****::*::***** *.:* *::** * : **::*:***:::.: ..* :* * . :: * *.: *: :*:::**:*** . *:: *** * *.*:**:::::**::* ** ::* : :.*** *.* * : *: * .: .** :** :* :*** .*.*:*:.* * *:* . :** * ** : **::: : *:: :**.:.:* *.* *: ** . ::***. : **:. .: :::: ****: . ", "identical_positions": 643, "similar_positions": 482, "identity": "40.59%" }, { "cls_id": "homologset.agr.MGI:1315204", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q923U9-1", "uniprot_id": "S40A1_RAT", "id": "Q923U9-1", "name": "Ferroportin", "aln": "MTKSRDQTHQEGCCGSLANYLTSAKFLLYLGHSLSTWGDRMWHFAVSVFLVELYGNSLLLTAVYGLVVAGSVLVLGAIIGDWVDKNARLKVAQTSLVVQNVSVILCGIILMMVFLHKNELLNMYHGWVLTVCYILIITIANIANLASTATAITIQRDWIVVVAGENRSRLADMNATIRRIDQLTNILAPMAVGQIMTFGSPVIGCGFISGWNLVSMCVEYFLLWKVYQKTPALAVKAALK-VEESELKQLTSPKDTE--PKPLEGTHLMGEKDSNIRELECEQEPTCASQIAEPFRTFRDGWVSYYNQPVFLAGMGLAFLYMTVLGFDCITTGYAYTQGLSGSILSVLMGASAITGIMGTVAFTWLRRKCGLVRTGLFSGLAQLSCLILCVISVFMPGSPLDLSVSPFEDIRSRFIHEEA--VSSTTKIPET--EMLMSNVSNVVNTVHEMSTKSVPIISVSLLFAGVIAARIGLWSFDLTVTQLLQENVIESERGIINGVQNSMNYLLDLLHFIMVILAPNPEAFGLLVLISVSFVAMGHLMYFRFAQKTLGNQIFV-CAPDEKEVTDESQPNTSVV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JHI9-1", "uniprot_id": "S40A1_MOUSE", "id": "Q9JHI9-1", "name": "Ferroportin", "aln": "MTKARDQTHQEGCCGSLANYLTSAKFLLYLGHSLSTWGDRMWHFAVSVFLVELYGNSLLLTAVYGLVVAGSVLVLGAIIGDWVDKNARLKVAQTSLVVQNVSVILCGIILMMVFLHKNELLTMYHGWVLTVCYILIITIANIANLASTATAITIQRDWIVVVAGENRSRLADMNATIRRIDQLTNILAPMAVGQIMTFGSPVIGCGFISGWNLVSMCVEYFLLWKVYQKTPALAVKAALK-VEESELKQLTSPKDTE--PKPLEGTHLMGEKDSNIRELECEQEPTCASQMAEPFRTFRDGWVSYYNQPVFLAGMGLAFLYMTVLGFDCITTGYAYTQGLSGSILSILMGASAITGIMGTVAFTWLRRKCGLVRTGLFSGLAQLSCLILCVISVFMPGSPLDLSVSPFEDIRSRFVNVEP--VSPTTKIPET--VFTTEMHMSNMSNVHEMSTKPIPIVSVSLLFAGVIAARIGLWSFDLTVTQLLQENVIESERGIINGVQNSMNYLLDLLHFIMVILAPNPEAFGLLVLISVSFVAMGHLMYFRFAQKTLGNQIFV-CGPDEKEVTDENQPNTSVV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NP59-1", "uniprot_id": "S40A1_HUMAN", "id": "Q9NP59-1", "name": "Ferroportin", "aln": "MTRAGDHNRQRGCCGSLADYLTSAKFLLYLGHSLSTWGDRMWHFAVSVFLVELYGNSLLLTAVYGLVVAGSVLVLGAIIGDWVDKNARLKVAQTSLVVQNVSVILCGIILMMVFLHKHELLTMYHGWVLTSCYILIITIANIANLASTATAITIQRDWIVVVAGEDRSKLANMNATIRRIDQLTNILAPMAVGQIMTFGSPVIGCGFISGWNLVSMCVEYVLLWKVYQKTPALAVKAGLK-EEETELKQLNLHKDTE--PKPLEGTHLMGVKDSNIHELEHEQEPTCASQMAEPFRTFRDGWVSYYNQPVFLAGMGLAFLYMTVLGFDCITTGYAYTQGLSGSILSILMGASAITGIMGTVAFTWLRRKCGLVRTGLISGLAQLSCLILCVISVFMPGSPLDLSVSPFEDIRSRFIQGES--ITP-TKIPEITTEIYMSNGSNSANIVPETSPESVPIISVSLLFAGVIAARIGLWSFDLTVTQLLQENVIESERGIINGVQNSMNYLLDLLHFIMVILAPNPEAFGLLVLISVSFVAMGHIMYFRFAQNTLGNKLFA-CGPDAKEVRKENQANTSVV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9I9R3-1", "uniprot_id": "S40A1_DANRE", "id": "Q9I9R3-1", "name": "Solute carrier family 40 member 1", "aln": "MDSPASKKPR---CERFREFFKSAKFLIYVGHALSTWGDRMWNFAVAVFLVELYGNSLLLTAVYGLVVAGSVLLLGAIIGDWVDKNPRLKVAQTSLVVQNSAVILCGALLMAVFQFKQQLSSMYDGWLLTTCYIMVISIANIANLASTAMSITIQRDWVVVVAGDDRSKLADMNATVRIIDQLTNILAPMLVGQIMAFGSHFIGCGFISGWNLFSMCLEYFLLWKVYQKTPALAFKAGQKDSDDQELKHLNIQKEIGNTESPVEASQLMTESS------ETKKDTGCCYQMAEPIRTFKDGWVAYYNQSIFFAGMSLAFLYMTVLGFDCITTGYAYTQGLNGSVLSLLMGASAVSGICGTVAFTWIRKKCGLIRTGFIAGVTQLSCLTLCVASVFAPGSPFDLSVSPFEEVLRHLFGDSGSLRESPTFIPTT------EPPIQANVTVFEEAPPVESYMSVGLLFAGVIAARVGLWSFDLTVTQLIQENVIESERGVINGVQNSMNYLLDLLHFIMVILAPNPEAFGLLVIISVSFVAMGHMMYFRFAYKSLGSRLFLFCSPEQKPDPNIPSLPNSV-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . .:. : * : :::.*****:*:**:*********:***:**************************:************.************* :***** :** ** .*::* .**.**:** ***::*:*********** :*******:*****::**:**:****:* *********** *****:*** .***********.***:**.*************.**. * :: ***:*. *: .*:*.::** .. * :::. *. *:***:***:****:****.:*:***.************************.**:**:******::** *******:*:****:***:::*::***** *** *** ****:********:: ::. . . * ** . . * * :. . :**.**********:************:**********:*********************************:**********:****** ::**.::* *.*: * . . .** ", "identical_positions": 378, "similar_positions": 110, "identity": "65.4%" }, { "cls_id": "homologset.agr.MGI:1315205", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O94813-1", "uniprot_id": "SLIT2_HUMAN", "id": "O94813-1", "name": "Slit homolog 2 protein", "aln": "---------MRGVGWQMLSLSLGLVLAILNKVAPQA------------------------------------CPAQCSCSGSTVDCHGLALRSVPRNIPRNTERLDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNHLQLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRDLEVLTLNNNNITRLSVASFNHMPKLRTFRLHSNNLYCDCHLAWLSDWLRQRPRVGLYTQCMGPSHLRGHNVAEVQKREFVCS----GHQSFMAPSCSVLH-CPAACTCSNNIVDCRGKGLTEIPTNLPETITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRAIQTMHLAQNPFICDCHLKWLADYLHTNPIETSGARCTSPRRLANKRIGQIKSKKFRCSAKEQYFIP-------GTEDYRSKLSGDCFADLACPEKCRCEGTTVDCSNQKLNKIPEHIPQYTAELRLNNNEFTVLEATGIFKKLPQLRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENVQHKMFKGLESLKTLMLRSNRITCVGNDSFIGLSSVRLLSLYDNQITTVAPGAFDTLHSLSTLNLLANPFNCNCYLAWLGEWLRKKRIVTGNPRCQKPYFLKEIPIQDVAIQDFTCDDGNDDNSCSPLSRCPTECTCLDTVVRCSNKGLKVLPKGIPRDVTELYLDGNQFTLVPKE-LSNYKHLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGNDISVVPEGAFNDLSALSHLAIGANPLYCDCNMQWLSDWVKSEYKEPGIARCAGPGEMADKLLLTTPSKKFTC-----------QGPVDVNILAKCNPCLSNPCKNDGTCNSDPVDFYRCTCPYGFKGQDCDVPIHACISNPCKHGGTCHLKEGEEDGFWCICADGFEGENCEVNVDDCE-DNDCENNSTCVDGINNYTCLCPPEYT---------GELCEEKLDFCAQDLNPCQHDSKCILTPKGFKCDCTPGYVGEHCDIDFDDCQDNKCKNGAHCTDAVNGYTCICPEGYSGLFCEFS--PPMVLPRTSPCDNFDCQNGAQCIVRIN--EPICQCLPGYQGEKCEKLVSVNFINKESYLQIPSAKVRPQTNITLQIATDEDSGILLYKGDKDHIAVELYRGRVRASYDTGSHPASAIYSVETINDGNFHIVELLALDQSLSLSVDGGNPKIITNLSKQSTLNFDSPLYVGGMPGKSNVASLRQAPGQNGTSFHGCIRNLYINSELQDFQKVPMQTGILPGCEPCHKKVCAHGTCQPSSQAGFTCECQEGWMGPLCDQRTNDPCLGNKCVHGTCLPINAFS---YSCKCLEGHGGVLCDEEEDLFNPCQAIKCKHGKCRLSGLGQPYCECSSGYTGDSCDREISCRGERIRDYYQKQQGYAACQTTKKVSRLECRGGCAGG-QCCGPLRSKRRKYSFECTDGSSFVDEVEKVVKCGCTRCVS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9R1B9-1", "uniprot_id": "SLIT2_MOUSE", "id": "Q9R1B9-1", "name": "Slit homolog 2 protein", "aln": "---------MSGIGWQTLSLSLGLVLSILNKVAPQA------------------------------------CPAQCSCSGSTVDCHGLALRSVPRNIPRNTERLDLNGNNITRITKIDFAGLRHLRVLQLMENRISTIERGAFQDLKELERLRLNRNNLQLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRDLEVLTLNNNNITRLSVASFNHMPKLRTFRLHSNNLYCDCHLAWLSDWLRQRPRVGLYTQCMGPSHLRGHNVAEVQKREFVCS----GHQSFMAPSCSVLH-CPAACTCSNNIVDCRGKGLTEIPTNLPETITEIRLEQNSIRVIPPGAFSPYKKLRRLDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTVAKGTFSALRAIQTMHLAQNPFICDCHLKWLADYLHTNPIETSGARCTSPRRLANKRIGQIKSKKFRCS---------------GTEDYRSKLSGDCFADLACPEKCRCEGTTVDCSNQRLNKIPDHIPQYTAELRLNNNEFTVLEATGIFKKLPQLRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENVQHKMFKGLESLKTLMLRSNRISCVGNDSFIGLGSVRLLSLYDNQITTVAPGAFDSLHSLSTLNLLANPFNCNCHLAWLGEWLRRKRIVTGNPRCQKPYFLKEIPIQDVAIQDFTCDDGNDDNSCSPLSRCPSECTCLDTVVRCSNKGLKVLPKGIPKDVTELYLDGNQFTLVPKE-LSNYKHLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGNDISVVPEGAFNDLSALSHLAIGANPLYCDCNMQWLSDWVKSEYKEPGIARCAGPGEMADKLLLTTPSKKFTC-----------QGPVDITIQAKCNPCLSNPCKNDGTCNNDPVDFYRCTCPYGFKGQDCDVPIHACISNPCKHGGTCHLKEGENAGFWCTCADGFEGENCEVNIDDCE-DNDCENNSTCVDGINNYTCLCPPEYT---------GELCEEKLDFCAQDLNPCQHDSKCILTPKGFKCDCTPGYIGEHCDIDFDDCQDNKCKNGAHCTDAVNGYTCVCPEGYSGLFCEFS--PPMVLPRTSPCDNFDCQNGAQCIIRIN--EPICQCLPGYLGEKCEKLVSVNFVNKESYLQIPSAKVRPQTNITLQIATDEDSGILLYKGDKDHIAVELYRGRVRASYDTGSHPASAIYSVETINDGNFHIVELLTLDSSLSLSVDGGSPKVITNLSKQSTLNFDSPLYVGGMPGKNNVASLRQAPGQNGTSFHGCIRNLYINSELQDFRKMPMQTGILPGCEPCHKKVCAHGMCQPSSQSGFTCECEEGWMGPLCDQRTNDPCLGNKCVHGTCLPINAFS---YSCKCLEGHGGVLCDEEEDLFNPCQMIKCKHGKCRLSGVGQPYCECNSGFTGDSCDREISCRGERIRDYYQKQQGYAACQTTKKVSRLECRGGCAGG-QCCGPLRSKRRKYSFECTDGSSFVDEVEKVVKCGCARCAS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9WVC1-1", "uniprot_id": "SLIT2_RAT", "id": "Q9WVC1-1", "name": "Slit homolog 2 protein", "aln": "---------MSGIGWQTLSLSLALVLSILNKVAPHA------------------------------------CPAQCSCSGSTVDCHGLALRIVPRNIPRNTERLDLNGNNITRITKTDFAGLRHLRILQLMENKISTIERGAFHDLKELERLRLNRNNLQLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRDLEVLTLNNNNITRLSVASFNHMPKLRTFRLHSNNLYCDCHLAWLSDWLRQRPRVGLYTQCMGPSHLRGHNVAEVQKREFVCSDEEEGHQSFMAPSCSVLH-CPIACTCSNNIVDCRGKGLTEIPTNLPETITEIRLEQNSIRVIPPGAFSPYKKLRRLDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTVAKGTFSALRAIQTMHLAQNPFICDCHLKWLADYLHTNPIETSGARCTSPRRLANKRIGQIKSKKFRCS---------------GTEDYRSKLSGDCFADLACPEKCRCEGTTVDCSNQKLNKIPDHIPQYTAELRLNNNEFTVLEATGIFKKLPQLRKINLSNNKITDIEEGAFEGASGVNEILLTSNRLENVQHKMFKGLESLKTLMLRSNRISCVGNDSFTGLGSVRLLSLYDNQITTVAPGAFGTLHSLSTLNLLANPFNCNCHLAWLGEWLRRKRIVTGNPRCQKPYFLKEIPIQDVAIQDFTCDDGNDDNSCSPLSRCPSECTCLDTVVRCSNKGLKVLPKGIPRDVTELYLDGNQFTLVP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M9QD64-1", "uniprot_id": "A0A8M9QD64_DANRE", "id": "A0A8M9QD64-1", "name": "Slit homolog 1 protein", "aln": "----------------MFVLKSVVLCALLCGAGAQS------------------------------------CPSQCSCSGTAVDCHGQSLRSVPRNIPRNVERLDLNANNLTKITKADFAGLKNLRVLQLMENKISSIERGAFQDLQELERLRLNRNNLQVLPELLFLGTTKLFRLDLSENQIQGIPRKAFRGSTEIKNLQLDYNQISCIEDGAFRALRDLEVLTLNNNNISRLSVASFNHMPKLRTFRLHSNNLLCDCNVAWLSDWLRQRPRLGLYTQCMAPPSLRGHNIAEVQKKEFMCT----GPQSHSS--CSVLQ-CPELCTCSNNVVDCRGKGLTEIPTNLPETITEIRLEQNSIKIIPAGAFAPYKRLRRIDLSNNQITELASDSFQGLRSLNSLVLYGNKITELPKGLFDGLFSLQLLLLNANKINCLRVDSFQDLQNLNLLSLYDNKLQTIAKGTFSSLRAIQTLHLAQNPFMCDCHLKWLADYLQDNPIETSGARCTSPRRLANKRIGQIKSKKFRCSAKEQYFIPGIHHINKCVEDYRSKLGGDCFADLACPEKCRCEGTTVDCSGQKLTKIPDHIPQYTAELRLNNNEFTVLEATGIFKKLPQLRKINLSNNKITDIEEGTFEGASGVNELILTSNRLEGVHYSMLKGLGGLRTLMLRSNRISCVNNGSFTGLSSVRLLSLYDNLITSMSPGAFDTLHSLSTLNLLANPFNCNCHLAWLGEWLRKKRIVTGNPRCQSPYFLKEIPIQDVAVQDFACEEGNDENSCSPLARCPAECSCLDTVVRCSNKGLKVLPKGIPRDVTELYLDGNEFTQVPLE-LSNYKHLTLIDLSNNQISTLSNHSFSNMSELLTLILSYNRLRCIPAKAFDGLKSLRLLSLHGNDIAVIPDGAFKDLSSLSHLALGANPLYCDCHMQWLSDWVKSGYKEPGIARCTGPGDMTDKLLLTTPSKKFTCTEVPGTCGFPVPGPVDVSILAKCNPCLSNPCKNDGTCSNHPVDFYRCTCPYGFKGQDCEEPIHACISNPCQNGGTCHLKDGEENTHWCVCPEGFEGDECEINIDDCE-DNDCENNSTCVDGINNYTCLCSPEYTAANNNEVEKGELCEDKLDFCASELNLCQHDSKCILTAKGFMCECTPGYTGEHCEVDFDDCEDNKCKNGAQCIDAVNGYTCVCPEGYSGLFCEFS--PPMVLPRTSPCDHYDCANGAQCVVKDT--DPVCQCLPGYEGVHCERLVSVNFINRESFLQIPSNLITEQANISLQIATDEDNGVLLYKGDNEHIAVELYRGRLRVSYDSGSYPPSAIYSVETINDGSFHVVELVAKDQSLSLSIDGGSPKSINTANSPSPVPSPAPLYLGGLPQQSGLASLRQGSGRNGSSFHGCIRNLYINDQLQDLTQFLLQEGVVPGCQPCQRSMCAHGQCHATGQSSFSCECEAGWTGPLCDQQVNNPCDGNKCIHGSCMAINSYS---YSCRCLPGFAGVLCDEEEQLS-PCQYIACKYGRCRVSGLGKAYCECNSGYTGQSCDREMACRGERVRDHYQTQQGYAACQSTEKVSRLECRGSCGDGTSCCAPLRSKRRKYTFQCTDGSSFVQEVEKVVKCGCTKCPS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P24014-1", "uniprot_id": "SLIT_DROME", "id": "P24014-1", "name": "Protein slit", "aln": "MAAPSRTTLMPPPFRLQLRLLILPILLLLRHDAVHAEPYSGGFGSSAVSSGGLGSVGIHIPGGGVGVITEARCPRVCSCTGLNVDCSHRGLTSVPRKISADVERLELQGNNLTVIYETDFQRLTKLRMLQLTDNQIHTIERNSFQDLVSLERLRLNNNRLKAIPENFVTSSASLLRLDISNNVITTVGRRVFKGAQSLRSLQLDNNQITCLDEHAFKGLVELEILTLNNNNLTSLPHNIFGGLGRLRALRLSDNPFACDCHLSWLSRFLRSATRLAPYTRCQSPSQLKGQNVADLHDQEFKCS----GLTEHAPMECGAENSCPHPCRCADGIVDCREKSLTSVPVTLPDDTTELRLEQNFITELPPKSFSSFRRLRRIDLSNNNISRIAHDALSGLKQLTTLVLYGNKIKDLPSGVFKGLGSLQLLLLNANEISCIRKDAFRDLHSLSLLSLYDNNIQSLANGTFDAMKSIKTVHLAKNPFICDCNLRWLADYLHKNPIETSGARCESPKRMHRRRIESLREEKFKCS----------------WDELRMKLSGECRMDSDCPAMCHCEGTTVDCTGRGLKEIPRDIPLHTTELLLNDNELGRISSDGLFGRLPHLVKLELKRNQLTGIEPNAFEGASHIQELQLGENKIKEISNKMFLGLHQLKT------------------------LNLYDNQISCVMPGSFEHLNSLTSLNLASNPFNCNCHLAWFAEWLRKKSLNGGAARCGAPSKVRDVQIKDLPHSEFKCSSENSE-GCLGDGYCPPSCTCTGTVVRCSRNQLKEIPRGIPAETSELYLESNEIEQIHYERIRHLRSLTRLDLSNNQITILSNYTFANLTKLSTLIISYNKLQCLQRHALSGLNNLRVLSLHGNRISMLPEGSFEDLKSLTHIALGSNPLYCDCGLKWFSDWIKLDYVEPGIARCAEPEQMKDKLILSTPSSSFVCR-----------GRVRNDILAKCNACFEQPCQNQAQCVALPQREYQCLCQPGYHGKHCEFMIDACYGNPCRNNATCTVLE--EGRFSCQCAPGYTGARCETNIDDCLGEIKCQNNATCIDGVESYKCECQPGFS---------GEFCDTKIQFCSPEFNPCANGAKCMDHFTHYSCDCQAGFHGTNCTDNIDDCQNHMCQNGGTCVDGINDYQCRCPDDYTGKYCEGHNMISMMYPQTSPCQNHECKHGVCFQPNAQGSDYLCRCHPGYTGKWCEYLTSISFVHNNSFVELEPLRTRPEANVTIVFSSAEQNGILMYDGQDAHLAVELFNGRIRVSYDVGNHPVSTMYSFEMVADGKYHAVELLAIKKNFTLRVDRGLARSIINEGSNDYLKLTTPMFLGGLPVDPAQQAYKNWQIRNLTSFKGCMKEVWINHKLVDFGNAQRQQKITPGCALLE----GEQQEEEDDEQDFMDET------PHIKEEPVDPCLENKCRRGSRCVPNSNARDGYQCKCKHGQRGRYCDQGEGSTEPPTVTAAS-----------------------------TCRKEQVREYYTEN----DCRSRQPLKYAKCVGGCGN--QCCAAKIVRRRKVRMVCSNNRKYIKNLDIVRKCGCTKKCY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * : :* . :: ** ***:* *** .* ***:*. :.***:*:.**:* * : ** * :**:*** :*:* :***.:*:** .*******.*.*: :** :. .::.* ***:*:* * : *:.*:*: .::.**** ***:*::: **:.* :**:*******:: *. *. : :**::** .* : ***:::*** :**. .*:. **:* .*. *:*:*:*:::.:** *: * .. . *.. : ** * *::.:**** *.**.:*..**: **:***** * :*. :*:.:::***:*****:*:.:* *::.**:.*.:********.:**..:*.** **********:*.*:* *:*:**:.*.*******::*::*:***..:::*:*:***:***:***:*:******: ********** **:*: .:** .::.:**:** :: * **.*:* * ** *:********:.: *.:** .** :*:** **:**: :.: *:* :**:* *:::..*::*.** .:***** ::*: * .*::: : .*: ** *:* *.**** *: : **:* *:**::*** :*******:***:.****:* : * .** * :::: *:*:. .:* *.. *.: .* . **..*:* .******.: ** :*:*** :.:****:.*:: : ", "identical_positions": 341, "similar_positions": 250, "identity": "21.1%" }, { "cls_id": "homologset.agr.MGI:1315208", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0AA76ENW5-1", "uniprot_id": "A0AA76ENW5_RAT", "id": "A0AA76ENW5-1", "name": "procollagen-proline 3-dioxygenase", "aln": "-MLRLLR-LLLLLLLPPPGSPEPSEPPGLAQLSPGAPPQAPDLLYADGLRAYSAGAWAPAVALLREALRSREVLGRARQDCGASCAAEPGAALPAQILGAPQPVSGPG----AWEPLLLRATLRRAECLTQCAAGRLGPGGAARFRVVSALRDAFRRREPYNYLQRAYYQLKKLDLAASAAHTFFVANPTHLQMREDMAKYRRMSAIRPQSFQDLVT--PLYWAAYDTGLELLKQQEAALALPKLEEALQGSLAQMESCRAGCEGPEEHQGAEEEEEK-GTQGGLYEAIAGHWIRVLQCRQHCVAETATRPGRSFPVRDFLPSQLRRLHEAYAQVGNVSQAVENVLSVLLFYPEDEAAKRALNQYQTQLG--ELRPDLGPREDVQRFILRSLGEKRQLYYAMEHLGTSFKDPDSWTPEAFIPKALREKLREDQE-----KKPWDSEPPQQKPPTYWKDALLLEGVTLTQDAQQLNGSERAVLDGLLTPAECGLLLQLAKDAAEAGARSGYRGRRSPHSPHERFEGLTVLKAAQLARAGTVGRPGAKLLLEVSERVRTLTQAYFSPERPLHLSFTHLVCRSAIEGEQEQRMDLSHPVHADNCFLDPDTGECWREPPAYTYRDYSGLLYLNDDFKGGDLFFTQPNALTVTAQVRPRCGRLVAFSSGGENPHGVWAVTRGRRCALALWHTWAPEHREQEWTEAKELLREEEEEEEENEEEEEILSRDPSPEPPSHKLQRVQDKAGKP--LRVREEL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CG70-1", "uniprot_id": "P3H3_MOUSE", "id": "Q8CG70-1", "name": "Prolyl 3-hydroxylase 3", "aln": "-MLRLLR-LLLLLLLPPPGSPEPPEPPGLAQLSPGSPPQAPDLLYADGLRAYSAGAWAPAVALLREALRSRAALGRARQECGASCAAEPGAALPSQLLGAPHPVSGPG----VWEPLLLRATLRRAECLTQCAVRRLGPGGAARLRVGSALRDAFRRREPYNYLQRAYYQLKKLDLAASAAHTFFVANPTHLQMREDMAKYRRMSAIRPQSFRDLVT--PLYWAAYDTGLELLEQREAALALPQLEEALQGSLAHMESCRAACEGPEEHQGAEEEGE--GSQGGLYEAIAGHWIRVLQCRQHCVADTATRPGRSFPVQDFLLSQLRRLHEAYAQVGNMSQAMENVLSVLLFYPEDEAAKKALNQYQTQLG--EPRPDLGPREDIQRFILRSLGEKRQLYYAMEHLGTSFKDPDSWTPEALIPKALRERLREDQE-----KKPWDHQPPQQKPLAHWKDALLMEGVTLTQDAQQLNGSERAVLDGLLTSAECGVLLQLAKDAAQAGARSGYRGRRSPHSPHERFEGLTVLKAAQLARAGTVGRPGAKLLLEVSERVRTLTQAYFSPERPLHLSFTHLVCRSAIEGEQEQRMDLSHPVHADNCVLDPDTGECWREPPAYTYRDYSGLLYLNDDFKGGDLFFTQPNALTVTAQVRPRCGRLVAFSSGGENPHGVWAVTRGRRCALALWHTWAPEHSEQEWTEAKELLQEEEEEEE----EEDILSRDPSPEPPSHKLQRVQEKAGKPRRVRVREEL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IVL6-1", "uniprot_id": "P3H3_HUMAN", "id": "Q8IVL6-1", "name": "Prolyl 3-hydroxylase 3", "aln": "-MLRLLRPLLLLLLLPPPGSPE---PPGLTQLSPGAPPQAPDLLYADGLRAYAAGAWAPAVALLREALRSQAALGRVRLDCGASCAADPGAALPAVLLGAPEPDSGPGPTQGSWERQLLRAALRRADCLTQCAARRLGPGGAARLRVGSALRDAFRRREPYNYLQRAYYQLKKLDLAAAAAHTFFVANPMHLQMREDMAKYRRMSGVRPQSFRDLET--PPHWAAYDTGLELLGRQEAGLALPRLEEALQGSLAQMESCRADCEGPEEQQGAEEEEDGAASQGGLYEAIAGHWIQVLQCRQRCVGETATRPGRSFPVPDFLPNQLRRLHEAHAQVGNLSQAIENVLSVLLFYPEDEAAKRALNQYQAQLG--EPRPGLGPREDIQRFILRSLGEKRQLYYAMEHLGTSFKDPDPWTPAALIPEALREKLREDQE-----KRPWDHEPVKPKPLTYWKDVLLLEGVTLTQDSRQLNGSERAVLDGLLTPAECGVLLQLAKDAAGAGARSGYRGRRSPHTPHERFEGLTVLKAAQLARAGTVGSQGAKLLLEVSERVRTLTQAYFSPERPLHLSFTHLVCRSAIEGEQEQRMDLSHPVHADNCVLDPDTGECWREPPAYTYRDYSGLLYLNDDFQGGDLFFTEPNALTVTARVRPRCGRLVAFSSGVENPHGVWAVTRGRRCALALWHTWAPEHREQEWIEAKELLQESQEEEE--EEEEEMPSKDPSPEPPSRRHQRVQDKTGRAP--RVREEL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B645-1", "uniprot_id": "A0ACD6B645_DANRE", "id": "A0ACD6B645-1", "name": "procollagen-proline 3-dioxygenase", "aln": "MALHSNSSSVYVALLFIINYICITAGSGLSSESSSGLLPPYDELYYRGVRAYFSEDWERAAEFLEKSISTRYKLLRIRRKCHDECLTAGDDKISEQDKED----------MIFWDLGVLEWIQVRAECVKFCMSRSVSP--AALLPVSSDIEYEFGTRNPYNYLQVTYYKLNKMTKAASAAHTFFVANPSHLEMRNNIEKYKRMLGVKEEFFQDREREHEQHWEMYDAAIQAESSSDWLKAVKMWNECVNETLKQTEECRAQCVTAP--RVIPEEPD---TVQGVYERAADLSLSMMSCQQTCVTLVSTRPGRVSAMEDFLPLQLEHLHIAQFKAGDLKGAVETLRSLLLFYPTDSDNLSNLDLYTQTLEGDTEAQQTGPAPEISKYVNRALQEKKLLYFGMANLDFKFSDPDLWTPEDVVPESLRETWRAEKEQLHEKLKQGDKMDEVDDSGFYAGGPIPVAGVSITLDDQGLNGTNRVVLDGVLSQSECDRVMQLATVAASAG--DGYRGRRSPHTPHEKFEGLTVLRALKLAQGGLVNQSDARLLHGIGETVKELMDSYFRTPSLLYFAYTHLVCRSAITGHQEGRSDLSHPVHVDNCILEPESRQCWREAPAFTHRDLSAVLYLNDDFEGGDFFFTDRDAKTVTATVKPKCGRLVGFTSGPVNPHGVTAVTKGRRCALALWFTTEKHHKDMEREEAEDLWAADGQSVVK---DEKADGENVVKSARSGRSQGKEKSKDRERVTGRRDEL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: : : ** . .**:. *... . * ** *:*** : * *. :*.::: :: * * * .* .* : . :. *: :*. **:*:. * :.* ** : * * :. * *:****** :**:*:*: **:********** **:**::: **:** .:: : *:* :* **:.:: : *: :*.:: :* : *.*** * . : ** : : *:** *. : ::.*:* ** .:***** .: *** **.:** * :.*::. *:*.: *:***** *. *: * * ** ::.::: *:* **: **:.* :*. .*.*** *** .:*::*** * ::* : * .. : . : : **::* * : ***::*.****:*: :**. ::***. ** ** .*********:***:*******:* :**:.* *. .*:** :.* *: * ::** . *::::********* *.** * *******.***.*:*:: :****.**:*:** *.:*******:***:***: :* **** *:*:*****.*:** ***** ***:*********.* .* : * **::* . :. :*. ..: .. * : * :.. .: *:**", "identical_positions": 284, "similar_positions": 199, "identity": "37.72%" }, { "cls_id": "homologset.agr.MGI:1315211", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5FVN0-1", "uniprot_id": "MBOA5_RAT", "id": "Q5FVN0-1", "name": "Lysophospholipid acyltransferase 5", "aln": "MASTADGDVGETLGQMRGLWPGVEDLSLNKLATSLGASEQALRLIFSIFLGYPLALFYRHYL-FYKDSYLIHLFHAFSGLSIAYFNFG-HQFYHSLLCVVLQFLILRLMGRTITAVFTTLCFQMAYLLAGYYYTATGDYDIKWTMPHCVLTLKLIGLSIDYYDGGKDRNSLSSEQQKYAILGVPSLLEVAGFSYFYGAFLVGPQFSMNHYMKLVKGQLTDVPGKMPNSTIPALKRLSLGLVYLVGYTLLSPHITEDYLLTEDYDTRPFWFRCMYMLIWGKFVLYKYVTCWLVTEGVCILSGLGFNGFEENGTVKWDACANMKVWLFETTPRFTGTIASFNINTNAWVARYIFKRLKFLGNKELSQGLSLLFLALWHGLHSGYLICFQMEFLIVIVEKQATNLIRDSPALS---SLASITALQPFYYLVQQTIHWLFMGYSMTAFCLFTWDKWLKVYRSIYFLGHVFFLSLLFTLPYVYKAMVPRKEKLKKRE-----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91V01-1", "uniprot_id": "MBOA5_MOUSE", "id": "Q91V01-1", "name": "Lysophospholipid acyltransferase 5", "aln": "MASTADGDMGETLEQMRGLWPGVEDLSLNKLATSLGASEQALRLIFSIFLGYPLALFYRHYL-FYKDSYLIHLFHTFTGLSIAYFNFG-HQFYHSLLCVVLQFLILRLMGRTVTAVITTLCFQMAYLLAGYYYTATGDYDIKWTMPHCVLTLKLIGLCIDYYDGGKDGNSLTSEQQKYAIRGVPSLLEVAGFSYFYGAFLVGPQFSMNHYMKLVRGQLTDIPGKMPNSTIPALKRLSLGLVYLVGYTLLSPHITDDYLLTEDYDNRPFWFRCMYMLIWGKFVLYKYVTCWLVTEGVCILSGLGFNGFDENGTVRWDACANMKVWLFETTPRFNGTIASFNINTNAWVARYIFKRLKFLGNKELSQGLSLLFLALWHGLHSGYLICFQMEFLIVIVEKQVSSLIRDSPALS---SLASITALQPFYYLVQQTIHWLFMGYSMTAFCLFTWDKWLKVYRSIYFLGHVFFLSLLFILPYIHKAMVPRKEKLKKRE-----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6P1A2-1", "uniprot_id": "MBOA5_HUMAN", "id": "Q6P1A2-1", "name": "Lysophospholipid acyltransferase 5", "aln": "MASSAEGDEGTVVALAGVLQSGFQELSLNKLATSLGASEQALRLIISIFLGYPFALFYRHYL-FYKETYLIHLFHTFTGLSIAYFNFG-NQLYHSLLCIVLQFLILRLMGRTITAVLTTFCFQMAYLLAGYYYTATGNYDIKWTMPHCVLTLKLIGLAVDYFDGGKDQNSLSSEQQKYAIRGVPSLLEVAGFSYFYGAFLVGPQFSMNHYMKLVQGELIDIPGKIPNSIIPALKRLSLGLFYLVGYTLLSPHITEDYLLTEDYDNHPFWFRCMYMLIWGKFVLYKYVTCWLVTEGVCILTGLGFNGFEEKGKAKWDACANMKVWLFETNPRFTGTIASFNINTNAWVARYIFKRLKFLGNKELSQGLSLLFLALWHGLHSGYLVCFQMEFLIVIVERQAARLIQESPTLS---KLAAITVLQPFYYLVQQTIHWLFMGYSMTAFCLFTWDKWLKVYKSIYFLGHIFFLSLLFILPYIHKAMVPRKEKLKKME-----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58HGI7-1", "uniprot_id": "A0AC58HGI7_DANRE", "id": "A0AC58HGI7-1", "name": "Lysophospholipid acyltransferase 5", "aln": "----------------------MAAPFMEKLAEYLDSPEPAVRLILSILIGYPFALAYRWFL-FHQSSTVLHLFHTITGLALATFNFAGSQVYHSLLCVVIQFLLLRLMGRTVTCVLTSFIFQMIYLLTGYYYTATDEYDIKWTMPHCVLTLKLIGLALDYYDGGKDQSKLSAEQKKSALGSTPSLLEVFGFSYFYGGFLVGPQFTLRNYQMLVSREMTDVPGQPPNSVVPALKRFCLGLITLSIFTIGGPRYSDSYYLTDEFAAHPFWYKCVYILLWVKINLYKYISCWLITEGVCVLAGLGYNGKNEKGEHQWDACANVRVWLFETTPLFTGTINSFNINTNAWVARHVFKRLRFLGNKLVSQMFTLLFLAIWHGLHSGYLICFSLEFLIVNVEKQAQSLVRDSPLLT---SIS-QSPLYPLVYVVQQSIHWLFMGYSLVPFCLFTFDKWLKVYFSIYFCGHIFFIAALLVLPYLRKVFVPRKRGSEKKED----------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VVX5-1", "uniprot_id": "MBOA5_DROME", "id": "Q9VVX5-1", "name": "Lysophospholipid acyltransferase 5", "aln": "--------------MAEFEEDLPHNGLMDGIASGVGVPVEALRLLLTILAGYPVAALYQKFISVIADKTVHHMFFAGCGAGLCYFNYGLDTYHSLIAILTTYFLVLLLRKKTQIFLAINFVFHMSYLLLGYFYTSSNDYDILWTMPHCILVLRMIGYGFDITDGLKEESELSKDQKETALKKPPSLLELLAFSYFPSGFLVGPQFPFRRYKAFVDGEFRQHEG----NVEAGVRRFGAGAFYLIVCQVGLRYLPDSYFLTPEFAQVSFVKRIYLLGFWAKFSLYKYISCWLLTEGALICIGLTYKGEDKNGQPDWSGCSNVKLKLLETGNTMEHYVQSFNVNTNQWVGQYIYKRLKFLNNRTISYGAALGFLAVWHGYHSGYYMTFLMEYMVVSTEKQITRFYTKVVLPQWGHILNNSDIYKLLYFITLKSYNVVYMGWCLTAFVFLKYERWIVVYGAVSYYGFTFLVLWAAFYHTFNHFFRSSSRKLAGEDQKLQDSNTDKLVEEKKPEDKKSE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: :* :. . *:**:::*: ***.* *: :: . .. : *:*.: * .:. **:. : : :. **:* * :* : .: *:* *** **:**::.:*** ******:*.*::** .* ** *: ..*: :*:: *: *****: .**** ..*******.:..* :* :: : * . ..::*: * . * : .:.* ** :: .* : : :* *: ****::***:***. : ** ::* :::* *..*:*::: *:** : : ***:*** **.::::***:**.*: :* :* ***:*** **** : * :*:::* .*:* : . : : ::. :: : ::**:.:..* ::.:::*: ** :: : *. *:: . : : . .. : ", "identical_positions": 136, "similar_positions": 160, "identity": "26.41%" }, { "cls_id": "homologset.agr.MGI:1315213", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V672-1", "uniprot_id": "G3V672_RAT", "id": "G3V672-1", "name": "", "aln": "MTHGEELGSDVHPDSIVLTYLEGLLMHQAAGGSGTAVDKKSAGHSEEDQNFNLSGSAFPTCQSNGPTLSTQTYQGSGMLHLKKARLLQSSEDWNAAQRKRLSDSIVNLNVKKEALLVGMVDSVPKGKQDSTVLASLLQSFSSRLQTVALSQQIRQSLK--EQGYALSHESLKVEKDLRCYGVASSHLKTLLKKSKTKDQKSGTTLPDVTPNLIRDSFVESSPHHVGQSGTKVMSEPLSCAARLQAVASMVEKRASPAASPKPSVACSQLALLLSSEAHLQQYSREHALKTQSAHQAASERLAAMARLQENGQKDMSSFQLSKGVSGHLDGQARTLPQSSKLAASKNNAAVFQNPMCGVPSSPKN---TSYKNSLERNNIKQAANNSLLLHLLKSQTIPTPMN--GHSQHERGSSF-ESSTPTTIDEYSDNNPSFTDDSSGDESSYSNCVPIDLSCKHRTEKPETE----RPVSLENLTQSLLNTWDPKVPGVDIKEDQDTSTNS-KLNSHQKVTLLQLLLGHKTEESVERNASPQEVHSDVTKFSPQNYTRTSVIESPSTNRTTPVSTPPLHTSSQGESPINLSQHSLVIKWNSPPYACSTPASKLTNTVTGHLMDLTKGKESQAEKPAPSEGAQNSATFSASKLLQNLAQCGMQSSVPGEEQRPSKQLLSG------HTDKPLGLIDRLNSPLLSNKANAAEENKAFSSQPAGPEPGLPGCEIENLLERRTVLQLLLGNSNKGKSEKKERAPALDEARQEHSERPGNEQILMVKIKSEPCDDFQTHNTNVHLNHDAKSTPFLGGTPTIQRSSAALPVSEDLKSEPASPQDFSFSKNGLLSRLLRQNQESYPADDQDKSHRNSELTPLESKNFCMVPKKRKLYTEPLENPFKKMKNSAVDNANNHGGPEVLYGSLLNQEELKFSRNDLDYKYSAGHSSASDGEHRSWARESKSFNVLKQLLLSENCVRDLSPHRSNSVTDNKKKGHKNNVPNSKPEFSISSLNGLMYGSPQPGSCV-DHRTFSYPGMVKTPLSSPFPEHLGCVGSRPEPGLLNGCSVPVPGEKGPIKWVITDVEKNEYEKDSPRLTKTNPILYYMLQKGG-NSVTTQETQDKDIWGEPSSAESLSQVTVKEEMLPAAETKAAFFNLRSPYNSHMGNNASRPHSTNGEAYGPLGNVLTIKKECE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CBD1-1", "uniprot_id": "NRIP1_MOUSE", "id": "Q8CBD1-1", "name": "Nuclear receptor-interacting protein 1", "aln": "MTHGEELGSDVHQDSIVLTYLEGLLMHQAAGGSGTAINKKSAGHKEEDQNFNLSGSAFPSCQSNGPTVSTQTYQGSGMLHLKKARLLQSSEDWNAAKRKRLSDSIVNLNVKKEALLAGMVDSVPKGKQDSTLLASLLQSFSSRLQTVALSQQIRQSLK--EQGYALSHESLKVEKDLRCYGVASSHLKTLLKKSKTKDQKSGPTLPDVTPNLIRDSFVESSHPAVGQSGTKVMSEPLSCAARLQAVASMVEKRASPAASPKPSVACSQLALLLSSEAHLQQYSREHALKTQNAHQVASERLAAMARLQENGQKDVGSSQLSKGVSGHLNGQARALP-ASKLVANKNNAATFQSPMGVVPSSPKN---TSYKNSLERNNLKQAANNSLLLHLLKSQTIPTPMN--GHSQNERASSF-ESSTPTTIDEYSDNNPSFTDDSSGDESSYSNCVPIDLSCKHRIEKPEAE----RPVSLENLTQSLLNTWDPKIPGVDIKEDQDTSTNS-KLNSHQKVTLLQLLLGHKSEETVERNASPQDIHSDGTKFSPQNYTRTSVIESPSTNRTTPVSTPPLYTASQAESPINLSQHSLVIKWNSPPYACSTPASKLTNTAPSHLMDLTKGKESQAEKPAPSEGAQNSATFSASKLLQNLAQCGLQSSGPGEEQRPCKQLLSG------NPDKPLGLIDRLNSPLLSNKTNAAEESKAFSSQPAGPEPGLPGCEIENLLERRTVLQLLLGNSSKGKNEKKEKTPARDEAPQEHSERAANEQILMVKIKSEPCDDFQTHNTNLPLNHDAKSAPFLGVTPAIHRSTAALPVSEDFKSEPASPQDFSFSKNGLLSRLLRQNQESYPADEQDKSHRNSELPTLESKNICMVPKKRKLYTEPLENPFKKMKNTAVDTANHHSGPEVLYGSLLHQEELKFSRNELDYKYPAGHSSASDGDHRSWARESKSFNVLKQLLLSENCVRDLSPHRSDSVPDTKKKGHKNNAPGSKPEFGISSLNGLMYSSPQPGSCVTDHRTFSYPGMVKTPLSPPFPEHLGCVGSRPEPGLLNGCSVP--GEKGPIKWVIADMDKNEYEKDSPRLTKTNPILYYMLQKGGGNSVTTQETQDKDIWREPASAESLSQVTVKEELLPAAETKASFFNLRSPYNSHMGNNASRPHSTNGEVYGLLGNALTIKKESE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P48552-1", "uniprot_id": "NRIP1_HUMAN", "id": "P48552-1", "name": "Nuclear receptor-interacting protein 1", "aln": "MTHGEELGSDVHQDSIVLTYLEGLLMHQAAGGSGTAVDKKSAGHNEEDQNFNISGSAFPTCQSNGPVLNTHTYQGSGMLHLKKARLLQSSEDWNAAKRKRLSDSIMNLNVKKEALLAGMVDSVPKGKQDSTLLASLLQSFSSRLQTVALSQQIRQSLK--EQGYALSHDSLKVEKDLRCYGVASSHLKTLLKKSKVKDQKPDTNLPDVTKNLIRDRFAES-PHHVGQSGTKVMSEPLSCAARLQAVASMVEKRASPATSPKPSVACSQLALLLSSEAHLQQYSREHALKTQNANQAASERLAAMARLQENGQKDVGSYQLPKGMSSHLNGQARTSS--SKLMASKSSATVFQNPMGIIPSSPKN---AGYKNSLERNNIKQAANNSLLLHLLKSQTIPKPMN--GHSHSERGSIFEESSTPTTIDEYSDNNPSFTDDSSGDESSYSNCVPIDLSCKHRTEKSESD----QPVSLDNFTQSLLNTWDPKVPDVDIKEDQDTSKNS-KLNSHQKVTLLQLLLGHKNEENVEKNTSPQGVHNDVSKFNTQNYARTSVIESPSTNRTTPVSTPPLLTSSKAGSPINLSQHSLVIKWNSPPYVCSTQSEKLTNTASNHSMDLTKSKDPPGEKPAQNEGAQNSATFSASKLLQNLAQCGMQSSMSVEEQRPSKQLLTG------NTDKPIGMIDRLNSPLLSNKTNAVEENKAFSSQPTGPEPGLSGSEIENLLERRTVLQLLLGNPNKGKSEKKEKTPLRDESTQEHSERALSEQILMVKIKSEPCDDLQIPNTNVHLSHDAKSAPFLGMAPAVQRSAPALPVSEDFKSEPVSPQDFSFSKNGLLSRLLRQNQDSYLADDSDRSHRNNEMALLESKNLCMVPKKRKLYTEPLENPFKKMKNNIVDAANNHSAPEVLYGSLLNQEELKFSRNDLEFKYPAGHGSASESEHRSWARESKSFNVLKQLLLSENCVRDLSPHRSNSVADSKKKGHKNNVTNSKPEFSISSLNGLMYSSTQPSSCM-DNRTFSYPGVVKTPVSPTFPEHLGCAGSRPESGLLNGCSMP--SEKGPIKWVITDAEKNEYEKDSPRLTKTNPILYYMLQKGG-NSVTSRETQDKDIWREASSAESVSQVTAKEELLPTAETKASFFNLRSPYNSHMGNNASRPHSANGEVYGLLGSVLTIKKESE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BGF6-1", "uniprot_id": "A0A8M2BGF6_DANRE", "id": "A0A8M2BGF6-1", "name": "", "aln": "MTHGVESGPETHQDSAALTYLEGLLMHPVNTGPAATATQRSEPVHNNEENANSVTRAFQLHNHGALSPEKGSPPSATSQHLKKARLLR-SGAWSE-DSQKQSSTGVEVNGQRREHYKGGLDGSGQ--GESTLLASLLQSFSSRLQSVALSQHISQSHKQLDRESSESAPVDP-KETYQSYGTASGRLKSLMRKSKHQNHN---TVPY-CRQSNQNRGSDS-PRSSQNSAQPTSSESMSCTERLKAVASMVRTRSSPAPSPKPSVACSQLALLLSSEAHLQQYSREQALKAQLTSRSASERLAAMATQQTQDNRPPSMGQPTTTPDMLSSLNAQNGTIPPLVVNSSKSSPSLSSPSTRPP---------KERRPFDRHGRPPQNCSSLLLLLLNNHNSQQQLTRNGHLEEDCGILPSCASSLQSDSEFSNPDNSLTKDSSDAES-LSSCSPIDLSMKSRTSCQKFEPCYSLPPLMDKLTESLVNKWKPETSVPKV-HEAVDLDASPDIKSQDKVTLMQLLLDRRNNEKVNKSSDHPGLRSD-SVISCLTAGSLKRIGTPEDSRTQSPQDRQ-------------------VASFSSVSPSYSFPSPVAQSSP---LDLCKSKAHSSEK--------MEPPFSASKLLQNLAQSGIKNLSPSPPPLHPHKLTSKRQSPVLELGKPQAFLNRLVTPAKQNSPPVLDEGSPKCEQ--SPASSLQI---ENLLEKRTVLQLLLGTASQKEKNSGHRVLEVTSRGMEKARVGSAKCDSSNGPPLDPNIKKEPVEENLQSDR---FNDGVYHLSRSSQHSPIAEVQDTIKSELCPTETA--AKFGLLSQLLKQQNAIYHSSPHTRLVRNTVKEEPMDFHSP-IPKKRKLCIELAERLSSELCQPPEDVTSDNPASGTPELKGRGLEKLKED----EPLGSPGNKTP-------LSRESQGFNVLKQLLLSENCLKELSQPRGTPSPFIPQANCAANGN-LTQSGFRQELSNLP---------------WYPYSFSSGPKTTPTPVDTPVWANVSPKASPKPVKKE--PEGSPEETFSREERSSP---DSPPLTRSNPILYYMLQRGN---------------------GQLRPEMRDQMQSPHCVMGDYEHRINSPVHRQFHSQREDSLNGSVEKW--------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1QMY9-1", "uniprot_id": "F1QMY9_DANRE", "id": "F1QMY9-1", "name": "", "aln": "MTHGEEPGPETHQDSAVLTYLEGLLMHQVAGGQGAAATQSGSQEQRNKDGTGHAQPNHGIRQE----QNRTYSHCGASQHFRKARLLN-SEAWTESETQRRSVPSVALNGQHEDHHSG-QNGSSQDKGESTLLASLLQSFSSRLQNVSLPQQIIQGLRPPDTSCQISKPAQEEKADVPCHRPASSHLQELVSKSKLQNHSN--SVPYQQRRSSHESFSQS-PKALQSSTPSPSPESLSCTERLKAVASLVNIRSSPAPSPKPSVACSQLALLLSSEAHLQQYSREHALKAKLSGRSASERLSAMATQQTPDKQPTTSSQTHG----LSLLQTKNGISSQMSTSSSRKSPSQISGQRRTESSMRTGHRFRERRPFEKQGRPSQNCSSLLLQLLNSHNTSQRINGQGHLKDDFITFGPLASPLFSDSEHSNPDSSLTKDSSDAESSYSSCSPIDLSLKGRTNVQTPVSTSSSP-VLDRLPESSFNMWKPESSPLKVSADHREMDSCSEMKPHHKVTLLQLLLDHKNNERVNKSLDNPDLLR--AVIPKVTSASTSSQSVFSTSRCKDPSDLSGHCGLSCKSPKLLPTLSQSRDSNCSASPYTLYGSPHSQCVP---LDLCKVKQPTSDVRV------KEPAFSASKLLQNLAQCGKQTPDISPP-TKAHLPPVKLMTQELKVNHPPTLIEKLTAPVQKNTP-LWEEATAKPSN--VPEATQQVSEIENLLERRTVLQLLLGNAPQKEK-VGNKRKREHSKTNSGEKPMHQTTTQANGPPLDVTIKTEPTEEGQTNDYNKMSQQCQNSVLEQRSSSASYLFQENIKQEPLSPEAS--TRDGLLCHLLKKRPKALQRNKLEDLNKSCVKEDSAETQGPTIPKKRKFSIEQEHQNSLIQPTSKLEHSCSIKEDNGSYFATEGLETREAR----DPSSPPEADSPPARFPPYESNENRSFNVLKQLLLSDNCLKELSQPR---STFSSPSHTVLNGNTIKQPCNGGEHQNLHRS-------------LSPSSASSKKTSGHRPESPQVTQQEPAKSKIDYSTMK--DLKVPTRMLNGDDQTQKYGLDSPRFTKTNPILYYMLQRSN---------------------AQLVKEG----EGLEVGLG------------QMQTKVKNESSGDTEAFEL------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**** * *.:.* ** .********** . * .:: : . .:.:. . . : . . *::*****. * *. . :: * . : :* ::. * :. : :**:*************.*:*.*:* *. : : * : .: **.:*: *: *** :::. .:* . :: :* .* .*.:**: **:****:*. *:***.***************************:***:: : : *****:*** * .:: * ::: .. .:. . :..::::. .**** **:.:. :. ** . : :*. : .*.*: : *:*.***. ** *.* ***** * * . * ::.:.:* .* *.*: . .: : . .::.:.****:****.::.:* *::. . : : : . . . .* . .. . :: . :** * * .: ...************.* :. : . .:* ::::* :* .*.. :* .. .: * . *****:*********.. : :. .: . . . : . : : . . :. ..: :*.* ..: :: ***.:**::. . :. . : :*****: * .. : : * : : .. :. :.*.:.**********:**:::** * . * . . ..* . . : * . . . . . * . . : .. *** :*::*********:.. .: :: .: . . . * : ", "identical_positions": 244, "similar_positions": 284, "identity": "20.63%" }, { "cls_id": "homologset.agr.MGI:1315214", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3UN16-1", "uniprot_id": "GP162_MOUSE", "id": "Q3UN16-1", "name": "Probable G protein-coupled receptor 162", "aln": "MARGGLGAEEASLRSNALSWLACGLLALLANAWIILSISAKQQKHKPLELLLCFLAGTHILMAAVPLTTFAVVQLRRQASSDYDWNESICKVFVSTYYTLALATCFTVASLSYHRMWMVRWPVNYRLSNAKKQALHAVMGIWMVSFILSTLPSIGWHNNGERYYARGCQFIVSKIGLGFGVCFSLLLLGGIVMGLVCVAITFYQTLWARPRRARQARRAGGSVGTKAGGLGGLGTRPAFEVPAIVVEDTRGKRRSSLDGSESAKTSLQVTNLVSAIVFLYDSLTGVPILVVSFFSLKSDSAPPWMVLAVLWCSMAQTLLLPSFIWSCERYRADVRTVWEQCVAIMSEDDGDDDGTCDDYTDGRVCKIRFDANGATGSGSRDPTQVKLLPGRHMLFPPLERVHYLQVPLSRRLSHDETNIFSTPRAPGSFLHKWSSSDDIRILPAQSRALGGPPEYLGQRHRLEDEEDEEEAEGGGLASLRQFLESGVLGSGGGPPRGPGFFREEITTFIDETPLPSPTASPGPSPRRPRPLGFSPRRLSLGSPDSRAVGLPLGLSAGRRCSLTGSEGSSRAWGRPWGPGNPIFPQLTL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q16538-1", "uniprot_id": "GP162_HUMAN", "id": "Q16538-1", "name": "Probable G protein-coupled receptor 162", "aln": "MARGGAGAEEASLRSNALSWLACGLLALLANAWIILSISAKQQKHKPLELLLCFLAGTHILMAAVPLTTFAVVQLRRQASSDYDWNESICKVFVSTYYTLALATCFTVASLSYHRMWMVRWPVNYRLSNAKKQALHAVMGIWMVSFILSTLPSIGWHNNGERYYARGCQFIVSKIGLGFGVCFSLLLLGGIVMGLVCVAITFYQTLWARPRRARQARRVGGGGGTKAGGPGALGTRPAFEVPAIVVEDARGKRRSSLDGSESAKTSLQVTNLVSAIVFLYDSLTGVPILVVSFFSLKSDSAPPWMVLAVLWCSMAQTLLLPSFIWSCERYRADVRTVWEQCVAIMSEEDGDDDGGCDDYAEGRVCKVRFDANGATGPGSRDPAQVKLLPGRHMLFPPLERVHYLQVPLSRRLSHDETNIFSTPREPGSFLHKWSSSDDIRVLPAQSRALGGPPEYLGQRHRLEDEEDEEEAEGGGLASLRQFLESGVLGSGGGPPRGPGFFREEITTFIDETPLPSPTASPGHSPRRPRPLGLSPRRLSLGSPESRAVGLPLGLSAGRRCSLTGGEESARAWGGSWGPGNPIFPQLTL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***** ********************************************************************************************************************************************************************************************************************.**. ****** *.****************:**************************************************************************************************:****** ****::*****:*********.*****:***************************************** ***************:********************************************************************************* *********:**********:********************.* *:**** .*************", "identical_positions": 564, "similar_positions": 16, "identity": "95.92%" }, { "cls_id": "homologset.agr.MGI:1315215", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VCS2-1", "uniprot_id": "Q9VCS2_DROME", "id": "Q9VCS2-1", "name": "Short-chain dehydrogenase/reductase 3", "aln": "-----------MSEVVRNTLVKLQAIIALIGLAAIT---------------------------------------PLLILVALLGRLIAKLCWCSAP-KSIAGE--VAVVTGAGHGLGRAISLELAKKGCHIAVVDINVSGAEDTVKQIQDIYKVRAKAYKANVTNYDDLVELNSKVVEE-------------------MGPVTVLVNNAGVMMHRN-MFNPDPADVQLMINVNLTSHFWTKLVFLPKMKELRKGFIVTISSLAGVFPLPYSATYTTTKSGALAHMRTLRMELDLENQ----KDIHVTTVLPSFLRTNSDVTQLTHTIGFGDVYPLFTGEEVAQRIVAGMVRGEAEITVPGMACLLYRVILILPADWQDRIILLFSRNKFKKLRDEHS------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VCR9-1", "uniprot_id": "Q9VCR9_DROME", "id": "Q9VCR9-1", "name": "Short-chain dehydrogenase/reductase family 16C member 6", "aln": "-----------MVETATTTTITRTTTAVPAGAVTVTGPTASATPTATQAAAQAHRNDETTRAIFNLKVIVFLLLLPLVLLAVFLKHLLDYLFALGLKEKDVSGK--VALVTGGGSGLGREICLELARRGCKLAVVDVNSKGCYETVELLSKIPRCVAKAYKNDVSSPRELQLMAAKVEKE-------------------LGPVDILVNNASLMPMTS-TPSLKSDEIDTILQLNLGSYIMTTKEFLPKMINRKSGHLVAVNALAGLVPLPGAGIYTATKYGIEGFMESLRAELRLSDC----DYVRTTVANAYLMRTSGDLPLLS-DAGIAKSYPGLPTPYVAEKIVKGVLLNERMVYVPKIFALSVWLLRLLPTKWQDYMLLRFYHFDVRSSHLFYWK-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "O88876-1", "uniprot_id": "DHRS3_MOUSE", "id": "O88876-1", "name": "Short-chain dehydrogenase/reductase 3", "aln": "------------------------MVWKWLGALVVF---------------------------------------PLQMIYLVTKAAVG--MVLPPKLRDLSRE--SVLITGGGRGIGRHLAREFAERGARKIVLWGRTEKCLKETTEEIRQMGTECHYFICDVGNREEVYQMAKAVREK-------------------VGDITILVNNAAVVHGKS-LMDSDDDALLKSQHVNTLGQFWTTKAFLPRMLELQNGHIVCLNSVLALSAIPGAIDYCTSKASAFAFMESL--TLGLLDC----PGVSATTVLPFHTST---EMFQGMRVRFPNLFPPLKPETVARRTVDAVQQNQALLLLPWTMNILIILKSILPQAALEEIHRFSGTYTCMNTFKGRT------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABZ3NNF2-1", "uniprot_id": "A0ABZ3NNF2_RAT", "id": "A0ABZ3NNF2-1", "name": "Short-chain dehydrogenase/reductase 3", "aln": "------------------------MVWKWLGALVVL---------------------------------------PLQMIYLVTKAAVG--LVLPPKLRDLSRE--SVLITGGGRGIGRHLAREFAERGARKIVLWGRTEKCLKETTEEIRQMGTECHYFICDVGNREEVYQMAKAVREKVQPTGTGCPHGSTAPSCPQVGDITILVNNAAVVHGKS-LMDSDDDALLKSQHVNTLGQFWTTKAFLPRMLELQNGHIVCLNSVLALSAIPGAIDYCTSKASAFAFMESL--TLGLLDC----PGVSATTVLPFHTST---EMFQGMRVRFPNLFPPLKPETVARRTVEAVQQNQALLLLPWTMNILIILKSILPQAALEEIHRFSGTYTCMNTFKGRT------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75911-1", "uniprot_id": "DHRS3_HUMAN", "id": "O75911-1", "name": "Short-chain dehydrogenase/reductase 3", "aln": "------------------------MVWKRLGALVMF---------------------------------------PLQMIYLVVKAAVG--LVLPAKLRDLSRE--NVLITGGGRGIGRQLAREFAERGARKIVLWGRTEKCLKETTEEIRQMGTECHYFICDVGNREEVYQTAKAVREK-------------------VGDITILVNNAAVVHGKS-LMDSDDDALLKSQHINTLGQFWTTKAFLPRMLELQNGHIVCLNSVLALSAIPGAIDYCTSKASAFAFMESL--TLGLLDC----PGVSATTVLPFHTST---EMFQGMRVRFPNLFPPLKPETVARRTVEAVQLNQALLLLPWTMHALVILKSILPQAALEEIHKFSGTYTCMNTFKGRT------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VKB8-1", "uniprot_id": "Q9VKB8_DROME", "id": "Q9VKB8-1", "name": "Short-chain dehydrogenase/reductase 3", "aln": "---------MIEREIIHTTPASKRIFDVLKDVLQFF---------------------------------------ELYVRILLELFVSLVQIVLPKKQKDVSGE--IVLITGTGHGIGRELALHYASLGSTVVCVDIDGKNNLQTVEKAKRLNLGEVYSYSCDVSKRDEVTALADRIKSD-------------------VGCISVLVNNVGIMPTHP-ILQQSAEEIQRVFDVNVFSQFWTIQAFLPHMQEKCRGHIICMSSIAGLVGISNLVPYCATKFAVRGLMEALHAELRQGPFR---DLIRTTTIFPYMTNTG---LCKHPKVKFPSILGLLDPKQVAKRIVEAHRTDLMEVTIPSCLLYINNWTRLLPDHCGLMLKDFIDSGVESDLI----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q07530-1", "uniprot_id": "YD114_YEAST", "id": "Q07530-1", "name": "Uncharacterized oxidoreductase YDL114W", "aln": "-------------------MVRKNKINRASGTTKHL------------------------------------------------KDFPSVILSLPSYNPSILSKNATALITGGSSGLGFELAKELSRRINKVIVADIQSFPTFAQVEYNN------IFYYQCDITSLDEIKNLKKAIERD-------------------HGNINIIINNAGVAHIKK-LEHMTNKEVEQLIDINLIGAYRIISTFAEDMIDNREGFIINIASVLGELTPARLTSYGASKGAMIGFHKCMSRHFRSLSTECNKTGIKTLLVCPGKIKTN---MFIDVPTPSKLLAPDIIPSQLALAIISAMEHNHLQTLNAPYYVNLVPFFKTLSWPYRHLLKHFSGMDHVTSTSPRAINPKRSA", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q06417-1", "uniprot_id": "TDA5_YEAST", "id": "Q06417-1", "name": "Uncharacterized oxidoreductase TDA5", "aln": "MNIDCLCRWVVLPLLRYPLLVALVLRWSLSDSISICLT---------------------------------IYTLLINAFLIANSYIKRSGQVAWKSLREFKNG--IVLITGGSKGLGRAIVSQLLQDYSNLTILNVDICPSSVRN--------TRVKDLICDLSDDEEVAALLNLLKRK------------------YKNEIRLIVNNAGVRANFTGFNGMERDNLDKIFKINTFAPLQFIQELAPSRHSTRQCYIVNIASILGILTPAKVAAYAASKAALIAFHQSYSFELQNEGVR----NIRTLLVTPGQLNT---EMFAGFKPPRQFFAPVIDITTLAAKIVRYCELGQRGQLNEPFYCSFAHLLMCVPYSLQRIVRSFSRIDCCLPDE----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .. .::** . *:* : . :: . :: : . . : :::**..: : .:* . : . .:: : :: . . * ::* . . . : : . . * : :* : . :. : ", "identical_positions": 11, "similar_positions": 55, "identity": "2.72%" }, { "cls_id": "homologset.agr.MGI:1316648", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LFP9-1", "uniprot_id": "A0ABK0LFP9_RAT", "id": "A0ABK0LFP9-1", "name": "", "aln": "MQLVDVHSTRDLWLSQAFLPSISPRPELCIFTSSQMEKEEETTRELLLPNWQGSGSHGLTIAQRDDG-VFVQEVMQNSPAARTGVVKEGDQIVGATIYFDNLQSGEVTQLLNTMGHHTVGLKLHRKGD-----RSPEPGQTWA-HEVFSSRSSEVVLSGDDEDYQRIYTTKIKPRLRSEDGVEGDLGETQSRT---------ITVTRRVTAYTVDVTGREGVKDIDISSPEFMIKIPRHEVTEISNTDVETQPGKTVIRLPSG------SGAASPTTGSAVDIRAGAISASGPELEGAS---------------------------HSKFQVTVPG-------TKVGSLDVNVKAKGLDLGGKGG-------------------------------------------------IQVPGVDVSSSLGGGS------------------VEGQGPSLQSGDIG-KVKIPTMK--------------------------------------MPKFGVS-AGLEGQIPEGGLNVSAPEFSVG-----------------------------------------------------------HKGDKPGLAIGG------------NIQAPHLEVSTSSVNIEGLEGKLKGPQITGPSLKGDLGLKG--TKLQGNIGMDDACASKIEGSITGPCVEIGTP-----------------------------DVDVHGLGGKLN-----VPKFSASGSKGEGVGIDVALP----TGKVTLPGVSGDVNLPEIATGGLEG----------KMKGAKVKTPEMIVQK----------------------------------------PKISMQDVDLSLGSCKLKGNMKVSAPEVKGGVKGPQVAVKGFGVDTETPNLEGTLTGPKLSSPSGKIGTCRISMADVDLNVAAPKGKG--GIDVTLPKVEGKVKGPEVDVKGPKTDISAPGVEVHGPEWNLKMP-----KFSIPGVKGEG----ADVNVPLAKGDISLSGPKVNVEAPDVNVEGLGGKLKGPDINLPEGSVKTPKISMPDVDLHIKGPKVKGEYDVTTPKLEGELKGPKVDTDIPQVDVHGP--NLKIPKMKMPKFSVPGFKAEGPEVDVNLPKVDIDISGTKVEVSAPDVSIEGPEGKLKGHKFKMPEMNIRAPKISMPDVDLHLKGPNVKGEYDVTVPRAEGEIKVPDVELKSAKVDIDVPN--------------------------------------------------------VDAQGPELHMKMPTIKMPKFGMPGFKAESPEVEMNLPKADIDVSGPKVDVKVPDVNTEGLEGKLKGPKLKMPEMNIKAPKISMPDVDLHMKGPKVKGEYDVTMPKLEGDLKGPKVDVSAPDVDVHGPDWNMKMPKIKMPKFTMPSLKGEGPELDVSMPKADVDISVPKLDISAPDLNLEGPEGKLKGPKFKMPEMHFKAPKMSLPDVDLDLKGPKMKGNVDMSAPKIEGEMKVPDVDIKGPNVDVQS-------PDWSLKMPKMKMPKFSMPTLKGEGPDVDVSLPKATIDVSGPKLDIETSDVSFEGPEGKLKGPKFKMPDMHFKAPKISMPDVDLNMKGPKVKGDMDVAVPEIEGKMKVPDVDIKGPKVDVDAPDVDVQGPDWHLKMPKVKMPKFSMPGFKAEGPEVDVSLSKADLDVSGPKVDIDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDFDLNLKGPKVKGDMDVSLPKVEGEIKVPEVDIKGPKVDIDVPDVDVQGPDWHLKMPKMKMPKFSMPGFKAEGPEVDVSLPKADLDVSGPKVDIDVPDVNIEGPEGKLKGPKFKMPEMHFKAPKISMPNIDLNLKGPKVKGDMDVAVPEIEGEMKVPDVDIKGPKVDINAPDVDVQGPDWHLKMPKIKMPKFSMPGFKAEGPEVDVSLPKADLDVSGPKVDIDVPDVN--------------------------------------------------------------------------IEGPDAKLKGPKFKMPEMNIKPQKISMPDVSLNLKGPKAKAEYDVSVPKVGGEIKAPAVDLKGP--KVEAPDVEVHGPDWHLKMPKVKMPKFSMPGFKAEGPEVDVNLQKANIDVSGPKMDIDVPDVNIEGPEGKLKGPKFKMPSMSIQTHKISMPDVGLNLKGPKLK---------------------------------------------------------------------------------------------------------------------------------------------SGVDVSLPKVEGDLKGPEVDVDVGDVDIECPEGKLKGPKFKMPDMHFKAPKISMPDVDLHLKGPKVKGDMDVAVPEIEGEMKVPDVDIKGPKVDINAPDVDVQGPDWHLKMPKVKMPKFSMPGFKAEGPEVDVSLPKADLDVSGPKVDIEVPDVNIEGPEGKLKGSKFKMPKLNIKAAKISMPDVDLNLKGPKLKGEIDASVPEMEADLRGPQIDVKGP-----------------------------SVDVEVP--DVDLECPEAKLKGPKFKMP-----------DMHFKAPKISMPDVDLHLKGPKVKGDMDVTVPKLEGELK-------------------------------------------------------------GPSVDVDVPDVDLECPEAKLKGPKFKMPDMHFKAPKISMPDVDLHLKGPKVKGDMDVTVPKLEGELKGP-------SVDVDVPDVDLECPEAKLKGPKFKMPDMHFKAPKISMPDVDFNLKGPKIKGDIDVSVPKLEGELKGPELDVKSPKLDANIPEVAVEGPEGKWKSPKFKMPDMHFKAPKISMPDIDLHLKSPKIKGDVDVDVPKLEGDLKGPNVDMSGP-------------------------------------------------------------DVEIEGPEGKLRGPKFKMPDMNIKAPKISMPDIDLHLKGPKVKGDVDASLPKVEGDLKGPEVDIKGPKVDIDVPDVDVQGPDWHLKMPKVKMPKFSMPGFKAEGP-------------EVDVSLPKADLDVSGPKVDIDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMP--DLHLKGPKIKGDVDVSLPKVEGEIKVPEVDIKGPKVDVDVPDVDVQGPDWHLKMPKMKMPKFSMPGFKAEGPEVDVSLPKADLDVSGQKVDIDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDFDLNLKGPKVKGDVDVSLPKVEGEIKVPEVDIKGPKVDIDVPDVDVQGPDWHLKMPKMKMPKFSMPGFKAEGPEVDVSLPKADLDVSGPKVDIDVPDVNIEGPDAKLKGPKFKMPEMNIKTPKISMPDLNLNLKGPNVKGDVDVSIPNVEGDLQGPSLDIKSPKLDVN---------------------------------------------------APDIDIHGP---------------------------------------------------------EGKLKGPKLKMPDMHVNMPKISMPDIDLNLKGSKVKGDVDISGPKLEGDIKTPKVDVKGPELDISASKVNIDAKG---KKSRFKLPKFNFSGSKVQTPEVDVKLKKPDVDVTAPKVDINAPEVEVQG---KVKGPKFKMPFLSISSPKVSMPDVELNLKGPKVKGELDATVPNLEGDFKSPKVDIKAPDVQLNAPDVDVHGQEWNLKMHKMKMPKFSVSGVKAEGPDVAVDLPKGDINIEGPSMNIEGPELNVECPEGSLKGPKFKMPEMNIKAPKISMPNIDLNLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKMDIDVPDVDVQGPDWHLKMPKVKMPKFSMPGFKAEGPEVDVSLSKADLDVSGPKVDIDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDIDLHLKGPKIKGDVDVSLPKVEGDLEGPHVDIKGPKVDINAPDVDVQGPDWHLKMPKMKMPKFSMPGFKAEGPEVDVSLPKADLDVSGPKVDIDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPNIDLNLKGPKVKGDVDMSLPKVEGEIKVPEVDIKGPKVDINAPD--------------------------------------------------------VDVQGPDWHLKMPKVKMPKFSMPGFKAEGPEVDVSLPKADLDVSGPKVDIDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPNIDLNLKGPKVKGDVDMSLPKVEGEIKVPEVDIKGPKVDIDVPDVDVQGPDWHL--------------------------------------------------------KMPKVKMPKFSMPGFKAEGPEVDVSLPKADLDVSGPKVDIDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMP--DLHLKGPKIKGDVDVSLPKVEGEIKVPEVDIKGPKVDINAPDVDVQGPDWHLKMPKMKMPKFSMPGFKAEGPEVDVSLPKADLDVSGPKVDIDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPNIDLNLKGPKVKGDVDMSLPKVEGEIKVPEVDIKGP-----KVDID---------------------------------------------------VPDVDVQGPDWH-----LKMPKVKMPKFSMPGFKAEGPEVDVSLPKADLDVSGPKVDIDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMP--DLHLKGPKIKGDVDVSLPKVEGEIKVPEVDIKGPKVDINAPDVDVQGPDWHLKMPKMKMPKFSMPGFKAEGPEVDVSLPKADLDVSGPKVDIDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPNIDLNLKGPKVKGDVDMSLPKVEGEIKVPEVDIKGPKVDINAPDVDVQGPDWHLKMPKVKMPKFSMPGFKAEGPEVDVSLPKADLDVSGPKVDIDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMP--DLHLKGPKIKGDVDVSLPKVEGEIKVPEVDIKGPKVDID---------------------------------------------------VPDVDVQGPDWH-----LKMPKMKMPKFSMPGFKAEGPEVDVSLPKADLDVTGPKVDIDVPDVNVGGPDVKVKGPKFKMPEMNIKAPKISMPDFDLHLKGPKVKGDVDASLPKME-----------GPGVDIDSPDVNIEGPEGKLKGPKFKMPDMHIKAPKISMPDFDLNLKGSKVKGDVDLSLPKVEGDLKG-------PEIDIECPEGKLKGPKFKMPDVHFKTPQISMSDIDLNMKGPKVKGDMDISVPKLEGDLKGTKVDVKGPKMDIDTPDIDIHGPEGKLKGPKFKMPDLHLKAPKISMPDVDLNLKGPKVKGDVDISLPKVEGDLKGPEVDIKGPKVDINAPDVDVQGP-------------------DWHLKMPKVKMPKFSMPGF-----KAEGPEVDVSLPKADLDVSGPKVDIDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDVDMSLPKVEGEIKVPEVDIKGPKMDIDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDLHLKGPKVKGDVDVSLPKVEGEIKVPEVDIKGPKVDVDVPD--------------------------------------------------------VDVQGPDWHLKMPKVKMPKFSMPGFKAEGPEVDVSLPKADLDVSGPKVDIDVPDVNVDGPDMKVKGPKFKMPEINIKAPKISMPDVDLELKGPKVKGAFDGS---VPKIEGTLKGPEIDMKGPGLDFEGPDAKLSGPNLKMPSLEVPVPKISGPDANVHLKTPNVGISGPKLGGGEVDLRGPKVDLETPSLDVHMESPDINIEGPDVKVPKFKKPKFGFG---AKSPKADIKTPTVDVTVPEAELSVETPEINIGGKGKKSKFKMPKIHMSGPKVKTKKQGFDLN---------VPGGEIDASLKVPDVDVS-----VAGPDAALK-AEVKSPKVKKTMFGK----MYFPDVEFDIKSPKFKAEAALPSPKLEGEIKVPDVDISSPGVNVEAPDIHVKAPKFKVPGVEAAGPKIEGNLKGPKVQAN----------LDTPDINIQGPEAKIKTPSFS---VSAPQVSIPDVNVKLKGPNIKGDVPSVG------LEGPDVDLQGPEGKIKFPKFSLPKISAPGVKMGGG-STEIHAQMPSLEAGLSTSDIKFEGPGVSLKGPGVDLPSVDLSLPKVSGPDL---DLNLKGPSLKGDVAASSP--SMKLHAPGLDMKGVAGKVQIGADGVKVSGTDATAALSVGAPDVTLKGSSLQGDLAVSG-DIKCPKVSVGTPEVSVEALEG---GVKLPQMKLPQFGISTPGSDLDINIKGPQVCGELQG-----SGTDVNLKGPQISAPGMDFNLEGPKVRGSLGATG-ELKGPSIGGGLPG--------------------ISIQGPEGNLQMPGIKASGCDVKVS----------SGQISGPEIKG------DLKGSGIGLHGAVPDLSVKGPSFNMASPESDFG--------VSLKGPKVKG-GVDVSGG-VSVPDINLGEGHMNVKGFGGEWK--------GPQVSSSVNLDTTKLVG-----NLHFSGPK-------IEGDVKGGQIGLQGPGLSVSGPQ---GHLESGSGKVTFPKMKIPKFTFSGRELTGREVGVDVNFPNVEANVQAGAGEGELEESAVKLK--KSKIKMPKFTFSKPKGKGG----VTGSPEASVSGSKGDLKSSKASLGS----LEGEAEAETSS-----PKGK-FSLFKSKKPRNRSNSFSDEREFSAPSTPTGTLEFAGGEG---------KGKHGKLKFGTFGGLGSKSKGHYEVTGSDDEAGKLQGSGVSLASKKSRLSSSSSNDSGTKLGIQLPEVEISVSTKKE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q616-1", "uniprot_id": "E9Q616_MOUSE", "id": "E9Q616-1", "name": "", "aln": "-----------------------------------MEKEEETTRELLLPNWQGSGSHGLTIAQRDDG-VFVQEVMQNSPAARTGVVKEGDQIVGATIYFDNLQSGEVTQLLNTMGHHTVGLKLHRKGD-----RSPEPGQTWT-HEVFSSRSSEVVLSGDDEDYQRIYTTKIKPRLRSEDGVEGDLGETQSRT---------ITVTRRVTAYTVDVTGREGVKDIDITSPEFMIKIPRHEVTEISNTDVETQPGKTVIRLPSG------SGPASPTTGSAVDIRAGAISASGPELEGAG---------------------------HSKFQVTVPG-------AKVGSLDVNVKAKGLDLGGKGG-------------------------------------------------IRVPGVDVSSSLGAGS------------------VEVQAPSLQSGDIG-KIKIPTMK--------------------------------------VPKFGVS-AGLDGQIPEVGLSVSAPESSVG-----------------------------------------------------------HKGDKPGLAIGG------------NIQAPHLEVNPSSVNIEGLEGKLKGPQITGPSLEGDLGLKG--TKLQGNIGMD-ACASKIEGSITGPSVEIGTP-----------------------------DVDVHGLGGKLNMPKMKVPKFSASGSKGEGIGLDVALP----TGEVTLPGVSGDVSLPEIATGGLEG----------KMKGAKVKTPEMIIQK----------------------------------------PKISMQDVDLSLGSCKLKGNMKTSAPEVKGDVKGPQMAVKGSRVDIETPNLEGTLTGPKISSPSGKIGACRISMADVDLNVAAPKGKG--GVDVILPNVEGKAKGLEVDVKGPKMDISAPDVEVHGPEWNLKMP-----KFSVPGVKGEG----LDVNVTLPEGDISISGPKVNVEAPNVNMEGLGGKLKGPDINLPEVSVKTPKISMPDVDLHIKGPKVKGEYEVTPPKLEGELKGSKVDIDTPQVDVHGP--DLKIPKMKMPKFSVPGFKAEGPEVDVNLPKADLDISGTKVEVSAPDVSIEGSEGKLKGHKFKMPEMNIRAPKISMPDVDLHLKGPNVKGEYDVTVPRAEGEIKVPDVELKSAKLDIDVPN--------------------------------------------------------VDVQGPELHMKMPKIKMPKFGMPGFKAESPEMEVNLPKSDIDVSGPNVDVKVPDVNIEGPEGKLKGPKLKMPEMNIKAPKISMPDVDLHMKGPKVKGEYDVTMPKLEGDLKGPKVDVSVPDVDVHGPDWNLKMPKIKMPKFSMPSLKGEGPELDVNMPKADVDISVPKLDISAPDLNLEGPEGKLKGPKFKMPEMHFKAPKVSLPDVDLDLKGPKMKGNLDMSAPKIEGEMKAPDVDIKGPNVDIKAPEVDVQGPEWSLKMPKMKMPKFSMPTLKGEGPDVDVSLPKATIDVSGPKLDIETSDVSLEGPEGKLKGPKFKMPDMHFKAPKISMPDVDLNMKGPKVKGDMDVTVPKIEGEMKVPDVDIKGPKVDISAPDVDVQGPDWHLKMPKMKMPKFSMPGFKAEGP--EVSLPKADLDVSGPKVDIDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMP--DLHLKGPKVKGDVDVSLPKVEGDLKGPDIDIKGPKMDINAPDMDVQGPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADIDVSGPKVDIEAPDVSIEGPEGKLKGPKFKMPDMHFKAPKISMPDVDLNIKGPKGKADVDASLPEVEGGVKVPDVDIKGPKVGIDAPDVEVHGPDWHLKMPKVKMPKFSMPGFKGEGPEVDI--PKANIDVSGPKVDIDVPDVN--------------------------------------------------------------------------IEGPDTKLKGPKFKMPEMNIKPQKISMPDVSLNLKGPKVKADCDVSVPKVGGEIKAPAVDIKGP--KVEAPDVEVHGPDWHLKMPKVKMPKFSMPGFKGEGAEVDVNLQKANIDVSGPKVDIDVPDVNIEGPEGKLKGPKFKMPSMNIQTHKISMPDVGLNLKGPKLK---------------------------------------------------------------------------------------------------------------------------------------------SGVDVSLPKVEGELKGPEVDVDVGDIDIECPEGKLKGPKFKMPDMHFKTPKISMPDVDLHLKGPKVKGDMDVTMPKIEGEMKVPDVDIKGPKVDINAPDVDVRGPDWHLKMPKVKMPKFSMPGFKAEGPEVDVNLPKADIDVSGPKVDIDVPDLDIEGPEGKLKGSKFKMPKLNIKAAKISMPDVDLNFKGPKLKGEIDASVPEMEADLRGPQVDIKGT-----------------------------NVDVKVP--DVDLECPDAKLKGPKFKMP-----------DMHFKAPKISMPDVDLHLKGPKVKGDMDVTVPKLEGELK-------------------------------------------------------------GPSVDVEVPDVDLECPDAKLKGPKFKMPDMHFKAPKISMPDVDLHLKGPKVKGDMDVTVPKLEGELKGP-------SVDVEVPDVDLECPDAKLKGPKFKMPDMHFKAPKISMPDVDLHLKGPKVKGDVDVTVPKLEGELKGPSVDVEVP-------DVDLECPDAKLKGPKFKMPDMHFKAPKISMPDVDLHLKGPKVKGDMDVTVPKIEGEMKVPDVDIKGPKVDINAPDVDVRGPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADIDVSGPKVDIDVPDVNIEGPEGKLKGPKFKMPDMHFKAPKISMPDVDFNLKGPKIKGDIDVSVPKIEGELKGPELDLKGPKLDANIPEVAVEGPEGKWKSPKFKMPDMHFKTPKISMPDIDLHLKSPKIKGEVDVDVPKLEGDLKGPNVDMSRPDIEIEGPEGKLKGPKFKMPEMNIKAPKISMPDFDLHLKGPKVKGDVDISLPKVEGDIKGPEVDIKGPKVDINAPDVDVQGPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADIDVSGPKVDIDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDVDVSLPKVEGEIKVPEVDIKGPKVDIDVPDVDVHGPDWHLKMPKIKMPKFSMPGFKGEGPEVDVSLPNADLDVSGPKVDIDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDLHL--KGPKVKGDVDVSLPKVEGDLKGPDVDIKGPKMDIN---------------------------------------------------APDMDVQGPDWHLKMPKMKMPKFSMPGFKAEGPEV---DVNLPKADLDVSGPKVDIDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDVDMSLPKVEGEIKVPEVDIKGPKVDIDVPDVDVHGPDWHLKMPKVKMPKFSMPGFKGEGPEVDVNLPKADLDVSGPKVDIDVPDVNIEGPDAKLKGPKFKMPEVNIKAPKISMPDLNLNLKGPNVKGDVDVSIPNIEGDLKGPSLDIKSPKLDVNAPDIDVHG------------------------------------------------------PEGKLKGPKLKMPDMHVSMPKISMPEIDLNLKGSKVKGDVDISGPKLEGDIKVPRVDLKGPEVDISAPKVNIDG---KAKKSRFKLPKFNFSGSKVQTPEVDVKLKKPDVDITAPKVDINAPEVEVQG---KVKGSKFKMPFLSISSPKVSMPDVELNLKGPKVKGDLDAAGPNLEGDFKGPKVDIKAPDVQLNAPDVDVHGPEWNLKMPKMKMPKFGVSGIKAEGPDVAVDLPKGDINIEGPSMNIEGPELNVECPEGSLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDVDVSLPKVEGEIKVPEVDIKGPKVDIDVPD--------------------------------------------------------VDVHGPDWHLKMPKVKMPKFSMPGFKGEGPEVDVSLPKANIDVSGPKVDIDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDVDVSLPKVEGEIKVPEVDIKGPKVDIDVPDVDVHGPDWHL--------------------------------------------------------KMPKIKMPKFSMPGFKGEGPEVDVSLPKADLDVSGPKVDIDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDVDVSLPKVEGEIKVPEVDIKDPKVDIDVPDVDVHGPDWHLKMPKIKMPKFSMPGFKGEGPEVDVNLPKADLDVSGPKVDIDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMP--DLHLKGPKVKGDVDVSLPKVEGDLKGPDVDIKGP-----KMDIN---------------------------------------------------APDMDVQGPDWH-----LKMPKMKMPKFSMPGFKAEGPEVDVNLPKVDLDVSGPKVDIDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDVDMSLPKVEGEIKVPEVDIKGPKVDIDVPDVDVHGPDWHLKMPKVKMPKFSMPGFKGEGPEVDVNLPKADLDVSGPKVDIDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMP--DLHLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKMDISAPDVDVHGPDWHLKMPKVKMPKFSMPGFKGEGPEVDVNLPKADLDVSGPKVDIEGPNVNIEGPEGKLKGPKFKMPDLHLKAPKISMPEIDLNLKGPKLKGDVDVSLPKVEGDLKGPEVDIKGPKVDIS---------------------------------------------------APDMDVHGPDWH-----LKMPKMKMPKFSMPGFKAEGPEVDVNLPKADIDVSGPKVDIDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDFDLHLKGPKVKGDVDASLPKMEGELKGPGIDIKCPTVDIDTPDVNIEVPEGKLKGPKFKMPDMHIKAPKISMPDFDLNLKGPKVKGDVDLALPNVEGDLKG-------PEIDIEGPEGKLKGPKFKVPDVQFKTPQISMSDIDLNVKGPKIKGDLDISIPKPEGDLKGPKVDIKGPKLDIDTPDIDIHGPEGKLKGPKFKMPDLHLKAPKISMPEVDLNLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDISAPDVDVHGP-------------------DWHLKMPKVKMPKFSMPGF-----KGEGPEVDVSLPKANIDVSGPKVDIDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDIDLNLKGP------------------------------------------------------------------------KVKGDVDVSLPKVEGEIKVPEVDIKGPKVDIDVPD--------------------------------------------------------VDVHGPDWHLKMPKVKMPKFSMPGFKGEGPEVDVNLPKADLDVSGPKVDIDVPDVNVEGPDMKVKGPKFRMPEINIKAPKISMPDVDLELKGPKVKGAFDGS---VPKIEGTLKGPEIDMKGPGLDFEGPDAKLSGPNLKMPSLEVSVPKITGPDANVHLKTPKVGISAPKLGGGEVDLKGPKVDLETPSLDVHMESPDINIEGPDVKVPKFKKPKFGFG---AKSPKADIKTPTVDVTVPEAELNVDSPEINIGGKSKKSKFKMPKIHMSGPKVKAKKQGFDLN---------IPGGEIDTSLKAPDVDVS-----VAGPDAALK-AEVKSPKVKKTMFGK----MYFPDVEFDIKSPKFKAEAPLPSPKLEGEIKVPDVDISSPGINVEAPDIHMKAPKFKVPGVEASGPKIEGNLKGPKVQAN----------LDTPDINIEGPEAKIKAPSFS---VSAPQVSIPDVNVNLKGPKIKGDVPSVG------LEGPNIDLQGPEGKIKFPKFSLPKISAPGVKMEGG-STEIGAQMPSLEGGLSTSDMKLEGPHLSLKGPGVDLPSVDLSMPKVSGPDL---DMNLKGPSLKGDLGASSP--SMKLHAPGLDLKGVGGKVHIGADGVKMSGIDATTALSVGAPDVTLKGPSLQGDLAVSG-DIKCPKVSVATPDVSLEASEG---AVKLPHMKLPQFGISTPGSDLDINIKGPQVCGELKG-----SGMDVNLKGPQISAPSMDFNLEGPKVKGSLGAAG-ELKGPAIGGALPG--------------------ISIQGPEGNLQMPGIKASGCDVKLS----------SGQISGPEIKG------DLKGSGLGLHGAVPDIGVKGPSFNVASPESDFG--------VSLKGPKVKG-GVDVSGG-VSVPDINLGEGHMSVKGSGVEWK--------GPQVSSSLNLDTSKLAG-----NLHFSGPK-------IEGDVKGGQTGLQGPGLSVSGPQ---GHLESESGKVTFPKMKIPKFTFSGRELIGREVGVDVNFPKVEANVQAGAGEGKWEESEVKLK--KSKIKMPKHIFSKSKGKGG----VTGSPEASISGSKGDLKSSKASLGS----LEGEVEAEASS-----PKGK-FSLFKSKKPRHRSNSFSDEREFSAPSTPTGTLEFAGGDA---------KGKHGKLKFGTFGGLGSKSKGHYEVTGSDDEAGKLQGSGVSLASKKSRLSSSSSNDSGTKVGIQLPEVELSVSTKKE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q09666-1", "uniprot_id": "AHNK_HUMAN", "id": "Q09666-1", "name": "Neuroblast differentiation-associated protein AHNAK", "aln": "-----------------------------------MEKEE-TTRELLLPNWQGSGSHGLTIAQRDDG-VFVQEVTQNSPAARTGVVKEGDQIVGATIYFDNLQSGEVTQLLNTMGHHTVGLKLHRKGD-----RSPEPGQTWT-REVFSSCSSEVVLSGDDEEYQRIYTTKIKPRLKSEDGVEGDLGETQSRT---------ITVTRRVTAYTVDVTGREGAKDIDISSPEFKIKIPRHELTEISNVDVETQSGKTVIRLPSG------SGAASP-TGSAVDIRAGAISASGPELQGAG---------------------------HSKLQVTMPG-------IKVGGSGVNVNAKGLDLGGRGG-------------------------------------------------VQVPAVDISSSLGGRA------------------VEVQGPSLESGDHG-KIKFPTMK--------------------------------------VPKFGVS-TGREGQTPKAGLRVSAPEVSVG-----------------------------------------------------------HKGGKPGLTI----------------QAPQLEVSVPSANIEGLEGKLKGPQITGPSLEGDLGLKG--AKPQGHIGVD-ASAPQIGGSITGPSVEVQAP-----------------------------DIDVQGPGSKLNVPKMKVPKFSVSGAKGEETGIDVTLP----TGEVTVPGVSGDVSLPEIATGGLEG----------KMKGTKVKTPEMIIQK----------------------------------------PKISMQDVDLSLGSPKLKGDIKVSAPGVQGDVKGPQVALKGSRVDIETPNLEGTLTGPRLGSPSGKTGTCRISMSEVDLNVAAPKVKG--GVDVTLPRVEGKVKVPEVDVRGPKVDVSAPDVEAHGPEWNLKMPKMKMPTFSTPGAKGEG----PDVHMTLPKGDISISGPKVNVEAPDVNLEGLGGKLKGPDVKLPDMSVKTPKISMPDVDLHVKGTKVKGEYDVTVPKLEGELKGPKVDIDAPDVDVHGPDWHLKMPKMKMPKFSVPGFKAEGPEVDVNLPKADVDISGPKIDVTAPDVSIEEPEGKLKGPKFKMPEMNIKVPKISMPDVDLHLKGPNVKGEYDVTMPKVESEIKVPDVELKSAKMDIDVPD--------------------------------------------------------VEVQGPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADVDISGPKVGVEVPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDVDLHMKGPKVKGEYDMTVPKLEGDLKGPKVDVSAPDVEMQGPDWNLKMPKIKMPKFSMPSLKGEGPEFDVNLSKANVDISAPKVDTNAPDLSLEGPEGKLKGPKFKMPEMHFRAPKMSLPDVDLDLKGPKMKGNVDISAPKIEGEMQVPDVDIRGPKVDIKAPDVEGQGLDWSLKIPKMKMPKFSMPSLKGEGPEVDVNLPKADVVVSGPKVDIEAPDVSLEGPEGKLKGPKFKMPEMHFKTPKISMPDVDLHLKGPKVKGDVDVSVPKVEGEMKVPDVEIKGPKMDIDAPDVEVQGPDWHLKMPKMKMPKFSMPGFKGEGREVDVNLPKADIDVSGPKVDVEVPDVSLEGPEGKLKGPKFKMPEMHFKAPKISMPDVDLNLKGPKLKGDVDVSLPEVEGEMKVPDVDIKGPKVDISAPDVDVHGPDWHLKMPKVKMPKFSMPGFKGEGPEVDVKLPKADVDVSGPKMDAEVPDVNIEGPDAKLKGPKFKMPEMSIKPQKISIPDVGLHLKGPKMKGDYDVTVPKVEGEIKAPDVDIKGPKVDINAPDVEVHGPDWHLKMPKVKMPKFSMPGFKGEGPEVDMNLPKADLGVSGPKVDIDVPDVNLEAPEGKLKGPKFKMPSMNIQTHKISMPDVGLNLKAPKLKTDVDVSLPKVEGDLKGPEIDVKAPKMDVNVGDIDIEGPEGKLKGPKFKMPEMHFKAPKISMPDVDLHLKGPKVKGDMDVSVPKVEGEMKVPDVDIKGPKVDIDAPDVEVHDPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADIDVSGPSVDTDAPDLDIEGPEGKLKGSKFKMPKLNIKAPKVSMPDVDLNLKGPKLKGEIDASVPELEGDLRGPQVDVKGPFVEAEVPDVDLECPDAKLKGPKFKMPEMHFKAPKISMPDVDLHLKGPKVKGDADVSVPKLEGDLTGPSVGVEVPDVELECPDAKLKGPKFKMPDMHFKAPKISMPDVDLHLKGPKVKGDVDVSVPKLEGDLTGPSVGVEVPDVELECPDAKLKGPKFKMPEMHFKTPKISMPDVDLHLKGPKVKGDMDVSVPKVEGEMKVPDVDIKGPKMDIDAPDVDVHGPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADVVVSGPKVDVEVPDVSLEGPEGKLKGPKLKMPEMHFKAPKISMPDVDLHLKGPKVKGDVDVSLPKLEGDLTGP------------------------------------SVDVEVP--DVELECPDAKLKGPKFKMP-----------EMHFKTPKISMPDVNLNLKGPKVKGDMDVSVPKVEGEMKVPDVDIRGPKVDIDAPDVDVHGPDWHLKMPKMKMPKFSMPGFKGEGPEVDVNLPKADVDVSGPKVDVEVPDVSLEGPEGKLKGPKFKMPEMHFKTPKISMPDVDFNLKGPKIKGDVDVSAPKLEGELKGPELDVKGPKLDADMPEVAVEGPNGKWKTPKFKMPDMHFKAPKISMPDLDLHLKSPKAKGEVDVDVPKLEGDLKGPHVDVSGP-------DIDIEGPEGKLKGPKFKMPDMHFKAPNISMPDVDLNLKGPKIKGDVDVSVPEVEGKLEVPDMNIRGPKVDVNAP--DVQAPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADVDISGPKVDIEGPDVNIEGPEGKLKGPKLKMPEMNIKAPKISMPDFDLHLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDINAPDVGVQGPDWHLKMPKVKMPKFSMPGFKGEGP-------------DGDVKLPKADIDVSGPKVDIEGPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDIDAPDVDVHGPDWHLKMPKIKMPKISMPGFKGEGPDVDVNLPKADIDVSGPKVDVECPDVNIEGPEGKWKSPKFKMPEMHFKTPKISMPDIDLNLTGPKIKGDVDVTGPKVEGDLKGPEVDLKGPKVDIDVPDVNVQGPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADVDVSGPKVDVEGPDVNIEGPEGKLKGPKFKMPEMNIKAPKIPMPDFDLHLKGPKVKGDVDISLPKVEGDLKGPEVDIRGPQVDID---------------------------------------------------VPDVGVQGPDWHLKMPKVKMPKFSMPGFKGEGPDV---DVNLPKADLDVSGPKVDIDVPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDMDVSLPKVEGDMKVPDVDIKGPKVDINAPDVDVQGPDWHLKMPKIKMPKISMPGFKGEGPEVDVNLPKADLDVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDLDLNLKGPKMKGEVDVSLANVEGDLKGPALDIKGPKIDVDAPDIDIHG------------------------------------------------------PDAKLKGPKLKMPDMHVNMPKISMPEIDLNLKGSKLKGDVDVSGPKLEGDIKAPSLDIKGPEVDVSGPKLNIEG---KSKKSRFKLPKFNFSGSKVQTPEVDVKGKKPDIDITGPKVDINAPDVEVQG---KVKGSKFKMPFLSISSPKVSMPDVELNLKSPKVKGDLDIAGPNLEGDFKGPKVDIKAPEVNLNAPDVDVHGPDWNLKMPKMKMPKFSVSGLKAEGPDVAVDLPKGDINIEGPSMNIEGPDLNVEGPEGGLKGPKFKMPDMNIKAPKISMPDIDLNLKGPKVKGDVDISLPKLEGDLKGPEVDIKGPKVDINAPD--------------------------------------------------------VDVHGPDWHLKMPKVKMPKFSMPGFKGEGPEVDVTLPKADIDISGPNVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDFDLNLKGPKMKGDVVVSLPKVEGDLKGPEVDIKGP--------------------------------------------------------------------------------------------------------------KVDIDTPDINIEGSEGKFKGPKFKIPEMHLKAPKISMPDIDLNLKGPKVKGDVDVSLPKMEGDLKGPEVDIKGPKVDINAPDVDVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKADLDVSGPKVDIDVPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDMDVSLPKVEGDMQVPDLDIKGP-----KVDIN---------------------------------------------------APDVDVRGPDWH-----LKMPKIKMPKISMPGFKGEGPEVDVNLPKADLDVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDFDLHLKGPKVKGDVDVSLPKMEGDLKAPEVDIKGPKVDIDAPDVDVHGPDWHLKMPKVKMPKFSMPGFKGEGPEVDVNLPKADIDVSGPKVDIDTPDIDIHGPEGKLKGPKFKMPDLHLKAPKISMPEVDLNLKGPKMKGDVDVSLPKVEGDLKGPEVDIKGPKVDIDVPDVDVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKADLDVSGPKVDIDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDFDLHLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDID---------------------------------------------------APDVDVHGPDWH-----LKMPKVKMPKFSMPGFKGEGPDVDVTLPKADIEISGPKVDIDAPDVSIEGPDAKLKGPKFKMPEMNIKAPKISMPDIDFNLKGPKVKGDVDVSLPKVEGDLKGPEIDIKGPSLDIDTPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDFDLHLKGPKVKGDVDVSLPKVESDLKG-------PEVDIEGPEGKLKGPKFKMPDVHFKSPQISMSDIDLNLKGPKIKGDMDISVPKLEGDLKGPKVDVKGPKVGIDTPDIDIHGPEGKLKGPKFKMPDLHLKAPKISMPEVDLNLKGPKVKGDMDISLPKVEGDLKGPEVDIRDPKVDIDVPDVDVQGP-------------------DWHLKMPKVKMPKFSMPGF-----KGEGPDVDVNLPKADIDVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMSIKAPKISMPDIDLNLKGP------------------------------------------------------------------------KVKGDVDVTLPKVEGDLKGPEADIKGPKVDINTPD--------------------------------------------------------VDVHGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVSLPKADIDVSGPKVDVDIPDVNIEGPDAKLKGPKFKMPEINIKAPKISIPDVDLDLKGPKVKGDFDVS---VPKVEGTLKGPEVDLKGPRLDFEGPDAKLSGPSLKMPSLEISAPKVTAPDVDLHLKAPKIGFSGPKLEGGEVDLKGP--KVEAPSLDVHMDSPDINIEGPDVKIPKFKKPKFGFG---AKSPKADIKSPSLDVTVPEAELNLETPEISVGGKGKKSKFKMPKIHMSGPKIKAKKQGFDLN---------VPGGEIDASLKAPDVDVN-----IAGPDAALK-VDVKSPKTKKTMFGK----MYFPDVEFDIKSPKFKAEAPLPSPKLEGELQAPDLELSLPAIHVEGLDIKAKAPKVKMPDVDISVPKIEGDLKGPKVQAN----------LGAPDINIEGLDAKVKTPSFG---ISAPQVSIPDVNVNLKGPKIKGDVPSVG------LEGPDVDLQGPEAKIKFPKFSMPKIGIPGVKMEGG-GAEVHAQLPSLEGDLRGPDVKLEGPDVSLKGPGVDLPSVNLSMPKVSGPDL---DLNLKGPSLKGDLDASVP--SMKVHAPGLNLSGVGGKMQVGGDGVKVPGIDATTKLNVGAPDVTLRGPSLQGDLAVSG-DIKCPKVSVGAPDLSLEASEG---SIKLPKMKLPQFGISTPGSDLHVNAKGPQVSGELKG-----PGVDVNLKGPRISAPNVDFNLEGPKVKGSLGATG-EIKGPTVGGGLPG--------------------IGVQGLEGNLQMPGIKSSGCDVNLPGV---NVKLPTGQISGPEIKG------GLKGSEVGFHGAAPDISVKGPAFNMASPESDFG--------INLKGPKIKG-GADVSGG-VSAPDISLGEGHLSVKGSGGEWK--------GPQVSSALNLDTSKFAG-----GLHFSGPK-------VEGGVKGGQIGLQAPGLSVSGPQ---GHLESGSGKVTFPKMKIPKFTFSGRELVGREMGVDVHFPKAEASIQAGAGDGEWEESEVKLK--KSKIKMPKFNFSKPKGKGG----VTGSPEASISGSKGDLKSSKASLGS----LEGEAEAEASS-----PKGK-FSLFKSKKPRHRSNSFSDEREFSGPSTPTGTLEFEGGEVSLEG--GKVKGKHGKLKFGTFGGLGSKSKGHYEVTGSDDETGKLQGSGVSLASKKSRLSSSSSNDSGNKVGIQLPEVELSVSTKKE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QZ50-1", "uniprot_id": "F1QZ50_DANRE", "id": "F1QZ50-1", "name": "", "aln": "------------------------------------MDDDQDTREVLFPQWMGADKHGLTIEQKGQGEIFVKEVKDESPAAHTGKVHEGDQIVGATIYFDNMSSEETAELLKTLNRHKVGLKLQNKGGDKSPCRSPMGTLSWEGRGSFGGSSSDILLSGDDEDYKRIYSKKIKPRLKSEDLAEGVDVRTERHSSTSSDGCTITTITRRITTYTVDMPGG-TSQQIDPSSPEFKIQLLQHEQEGGDSSQIGLPHSSLVSSEHGGKNLGDISFGGPHVTGSSVKHCSTGSIRATSELDGSGREITINVSDTGLSGGRGQRFTEHFVGTETSLEGNFSGRVTTGLEKQVGNISSPVEASFKALSTKGGTVKGSVLETHGSGFSIIGGSKGSIGRESSSEVLKDGSDDLTKLSKFSIDVQRPKVNIKRSEADISQGSDFAIPDMDSKAKLPKVETSGSVVHSKEIGGEFKLPNVKGSKQFTVESPNVEANFNNQNLKDVSQRGFSLTGNQDLPHPSFRMKGTNLEDSNLGADMDISGPEFQVQRCEIKVKDTQFDVPSVTGQGISISDVDLTLKEQKRGVNVCVQNIESNVMTPKVEIKGQSLKGVEDGFMMKGPNIDANAANAKIEIKTPNIDMKTQEFNIEGPERKYKVSNVKVPSISGTSVQNVNITGPAGTAGDFSISAPKTEGDIKAPSIEIKGPKLMGSNVDLNLPKAEIENKQTGVEIRLPSKPDIEGADGKITYPEFKKTSITGPNISMPEVNLNIKGQKLKGSVETSVPKVEGHIKEPEVAVERQDGPERGFGMPIFGLKGQKVEGPGFDVKISKADVELKESNLNIKASKLDTERSDGTIKDNKIVMPSVSGPTIYMPGADFNLTGSKLKGDVDASLPKIEGDIKAYDMDYKAPKHNIDRP--EGKLKSPEFNMPS--VSGPNISMPDVDLNLNGSKLKADVDVDVSVSKVKGDIKVPDVDIKPPKVDIKVPEVEIKGPKFNMPSISDSNNSMPNVDFNLKGQKMKSDVDVSVLKVKGDLKDPGVNIKAPNFEIEGSDGKIK--DSKLSMSSISGPNISMPDVDFNLKESKLKGDVDVSVPKVEGDIKAPKIEHEGP--DLEGG---FKMPKINIPKFGSKGPKMEGPDMDVKFPKTDIDIKAPDVDVKAAQLDIEGPEGKVKGSKFKMPFS---GPTISMPDVDFNLKGRKMKGDVDVSIPKVEGDVKVPGVEIKGPRVDIEGPEGKIKGSKFSMPSISVPNVSMPDVDFNLKGSKLKGDVNVSVPKMEGDVKAPKVELEGPDIEGPEGGFKMPNIKMPKFGSKGPKVEKPDIDVKIPKTDIDIKAPDVDIKAPELDIEGPEGKVKGSKFKMPFS---GPTISMPDVDFNLKGPKLKGDVDVSVPKVEADIKAPKVELEGP--EIEGPEGGFKMPKIKMPQIGFKGPKVEGPDVDVKIPKTNIDIKAPDVDIKGPEIDIEGPEGKVKGSKFKIP---FSGPNISMPDVDFNLKGPKLKG--DVSVPKVKGDIKAPKVELEGP--EIEG-------PEGGFKMPTIKMPKFGFKGPKVEGPGMDVKIPKTDIDIKGPDVDIKAPELDIEAPEGNIKDPKLKMPSLSR--PTISMPDVDFNLKGQKLKGDVDVSVPKMQGEIKAPKVELEGQ---------DIAGPEGGFKMPKIKLPQFGFKGPKVEGPDVDVKIPKTEIDIKAPDVDIKGPEIDIEAPEGKVKGSKFKIP---FSGPTISMPDVDFNLKGPKLKGDVDVSVPKVEGDIKAPKGDLEGP---------EIEVPEGGFKMPTIKMPKFGSKGPKVEKPDIDVKIPKTDIDIKAPDVDIKAPVLDIEGPEGKVKGSKFKMP---FSGPTISMPDVDFNLKGPKLKGDVDVSVPKVKGDIKAPKVELEGP---------EIEGPEGGFKMPTIKMPKFGFKGPNVEGPGLDVKIPKTDIDIKGPDVDIKAPKLD--------------------------------------------------------------------------IEAPEGNIKDPKLIIPSLSR--PTISMPDVDFNLKGPKLKGDVDVSVPKVQGDIKAPKVELEGS---------DIAGPEGGFKMPKIKMPQIGFKGPKVEGPDVDVKIPKTDIDIKAPDVDIKGPEIDIEGPEGKVKGSKFKIP---FSGPTISMPDVDFNLKGPKLKGDVDVSVPKVEGDIKAPKVELEGPEIDGPEGGFKMPTIKMPKFG-----------------------------------------------------------------------------------------FKGPKVEGPDVDVKIPKTDIDIKAPDVDIKGPEIDIEGPEGKVKGSKFKIP---FSGPTISMPDVDFNLKGPKLKGDVDVSVPKVEGDIKAPKVEIEGP---------EIEGPEGGFKMPTIKMPKFGFKGPKVEGPGMEVKIPKTDIDIKGPDVDIKAPELDIEAPEGNIKDPKLKMPSLSR--PTISMPDVDFNLKGPKLKGDVDVSVPKVQGDIKASKVELEGPDIAGPEGGFKMPKIKMPQIGFKGPKVEGPDVDVKIPKTDIDIKAPDVDIKGPEIDIGGPEGKVKGSKFKIPFSGPNISMPDVDFNLKGPKLKGDVDVSVPKVEGNIKTPKVELEGPEIE---------GPEGGFKMPTIKMPKFGFKGPKVEGPGMDVKIPKTDIDIKGPDVDIKALELDIEAPEGNIKDPKLKMPSLSR--PTISMPDVDFNLKGPKLKGDVDVSVPKVQGDIKAP---------KVELEGSDIAGPEGGFKMPKIKMPQIGFKGPKVEGP-------------DVDVKIPKTDIDIKAPDLDIKSP-------EIDIEGPEGKVKGSKFKIP---FSGPKISMPDVDFNLKGPKLKGDVDVSVPKVEGDITAPKVELEGPEIE---------GPEGGLKMPTIKMPKFGFKGPKVEGPGMDVKSPKTDIDIKGPDVDIKAPELDIEAPKGNIKDPKLKMPSLSR--PTISMPDVDFNLKGPKLKGDVDVSVPKVQGDIKAPKVELEGS---------DIAGPEGGFKMPKIKMPQIGFKGPKVEGP-------------DVDVKIPKTDIDIKAPDLDIKSPEIDIEGPEGKVKGSKFKIPFS---GPKISMPDVDFNLKGPKLKGDVDVSVPKVEGDITAPKVQLEGP---------EIEGPEGGFKMPTIKMPKFGFKGPKVEGPGIDVKSPKTDIDIKGCDVDIKAPELDIEAPEGNIKDPKLKMPSLTR--PTISMPDVDFNLKGPKLKGDVNVSVPKVEGDIKAPKLELEGP---------EIEGPESGFKMPKFKMPHIGFKGPKLESPDLDVKIPKADFEVKSPDLDLKTPELDIEGPEGKVKGSKFKMPFS---GPKISMPDVDFNLKGPKLKGEVDVSVPKVKGDIKATEVDIKTPQIDIEGPEGKPKGSKFSIPSISGPNISMPDADFSLKGPKLKGDVDVSVPKVEGDIKAPNVEIEGPDIKGPEGGFKMPKIKMPRFGFKGPKVEGPDVEVPKTDIDIKAPDVDIKSPELDFEGPEGKVKGSKFKMP---FSGPTISMPDVDFNLKSPKLKG--DVSVPKVEGDIKAPKVELEGP---------EIEGPEGGFKMPNIKMPKFGFKGPKVEGPDVDIKIPKTDIDIKAPDVDIKGPEIDIEGPEGKVKGSKFKIPFS---GPTISMPDVDFNLKGPKLKGDVDVSVPKVKGEIKAPDVVVKTPKVDIEG-------------------------------------------------------------PEGKLKGPKFNIP--SISGPNISMPDVDFNLKGPKLKG--DVSVPKVEGDIKAPKVELEGPEIEGPES---------GFKMPKFKMPHIGFKGPKVEGPDVDVKIPKTEIDIKEPDLDIKGPELDIEGPEGKVKGPKWKMPSFSR--PTVSVPDVDFNLKGPKLKGDVDVSLPKVEGGVKAPKVELEGP---------DIEGPEGGFKMPKFRLPKFGFKGPKVERPDMDMKIPKADFEVKSPDLDIKSPEIDIEGPEGKVKGPKLKMPSF--PVPKISMPDVDFNLKGPKLKGDFDVSVPKVEGDFKAPDVDVKTPKVDMEGPEGKFKGPKFQMPSFSGPNISMPDVDFNIKGPKLKGDVDVSVPKVQGDIKAPKIELEGPDIEGPEGGFKMPNIKMPKFGFKGPKVEGPDMDVKIPKSDFEVKSPDLDIKSPEIDIEGPEGKVKGPKFKIPSF--TGPKISMPDVDFNLKGPKLKGDVDVSVPKVEGDIKLPGLDVEAPKVDMEGSEGKLKGPKFSMPSISGPNFSLPNVDFNLKGPKLKGDVDVSIPKVEGGVKAPKVEIEGPDIESSEGGFKMPNIKMPKFGFKGPKVEVPDMDVKIPKADFEVKSPDLDIKSPEIDMEGPEGKVKGPTLKMPSFS--GPKISMPDVDFNLKGPKLKSDVDVSVPKVEGGIKAPKVEIEGP---------DIEGREGGFKMPNIKMPKFGFKGPKVEGPDMDVKIPKSDFEIKSPDLDIKSPEIDIEGPEGKVKGPKFKIPSF--SGPKISMPDVDFNLKGPKLKGDVDVSVPKVEGDIKLPGLDVKAP-----KVDMEGSEGKFKGPKFSMPSISGPNFSLPNVDFNLKGPKLKGDVDVSVPKVEGGVKAPKVELEGPDIESPEGGFKMPNIKMPKFGFKGPKVEGPDMDVKIPKADFEVKSPDLDIKSPEIDIEGPEGKVKGPTLKMPSF--SGPKISMPDVDFNLKGPKLKSDVDVSVPKVEGGIKAPKVEIEGP---------DIEGREGGFKMPNIKMPKFGFKGPKVEGPDMEVKIPKADFEVKSPDFDIKSPEIDIEGPEGKVKGPKFQMPSVSR--PKMSMPDVDFNLKGPKLKGDVDVSVPKVEGGIKAPKVEIEGP---------DIEGREGGFKMPNIKMPKFGFKGSKVEGPEMDVKIPEADFEVKSPDLDIKSPEIDIEGPEGKVKGPKFQMP--SVSLPKISMPDVDFNLKGPKLKGDVDVSVPKVEGDIKLPSLDVEAPKIDFEGSEGKLKGPKFSMPSISGPNFSLPNVDFNLKGPKLKGDVDVSVPKVEGGVKAPKVELEGPDIESPEGGFKMPNIKMPKFGFKGPKVEGPDMDVKIPKADFEVKSPDLDIKSPEIDIEGPDGKVKGPTLKMPSL--SGPKISMPDVDFNLKGPKVKGDVDVSVPKVEG-------DIKVPGLDIKAPKVDIEGPEGKLKGPKINIP--SISGPNISLPTVDFNLKGPKLRGDVDVSVPKVKGDVKAPDLDIKTPEIDIEGAEGKIKGPKFRIPSVSM--PKISMPEVDFNLKGPKLKGDVDFSVPKVEGDVKAPDVHIKGPEVDVET-------PEGKITGSKFKGP--SFSGPNISLPDVDFNLKGPKLKGGVDVSVPKVQGDIKATDFNINLPNIDGDIPEGKVKGPKLKMPSLSGPEGSIEVNLPETNVKKPKFKMPKFKFPSFGHKGPKVEGPDVDVKIPKADIKFKSPDLDNESPELNIEGPKGKIKASKFSMP--TISGPKVSMPDVDLNLKRP------------------------------------------------------------------------KLKGDVDVSVPKVEGNISVPDVDLKSPEVEFEGPEGKIKGPKGKIPLLSGPNISMPHVDFNLKGPKLKSDVDVSVLKVEGDIKTPKIEHEGPDIEGPEGGFKMPKLKIPQFGFKGPKVEGPDMDVKIPKTDIDINAPDVDIKAPELDIDGPEGKIKGPKLTKPSL--SGPTISMPDVDFNLKGRKMKGDVDVS---VPKLQGDIKVPGMDIKGPQVDIEGPEGKIKGSKFSMP--SISGPKISMPNVDFNLK-------GPKLKG-DVDVTVPKVEGDMKAPKVELEGPDIEGPEGGFKMPKVKMPKIGFKGPKVEGPDVNVQIPKTDIDINAPDVDIKSPELEIEGPEGKVKGHKLKMPFSGPTISMPDVDFNLKGLKLKGDVDASAPKVKGDIKIPNVDIKGPEVDIEGPGRKFKGPKFQMPSVSGPNISMPDVDFTMPDVDVNLKGPKLKGDVDVSVPKVEGHIKAPKVDIEGPDFDVDGPEVGFKMP--KLPSLGLKGPNVEGPEIGVKIPKTNIDVKAPGVDIESPDLNIEGPDGKIKSPKFKIPTVSIPKVPMPDVDFNLKGPKLKGDVDVSVPKMEGDINGAKVKFEGPGYEGPEGGFKIPKMPSFGLKGPNVEGPDVDIKLPKAGVDVKGPEIEVKSPDLEIKGHEGKIKGPNFKMPSLSGPQISMPDINIKGPKVKGDMGISGPKTGGDLKSAKVDIKGPHVDLESPEGGLKMP---TIKMPAFGFKGPKVDGPDIDFNLPKTDVDMKGPEIDIKTADLDTDGLGGGLKNVKFPKFKGPHFGIKTSGGSLSVPEQDVEATIDAKSPDVTLSGPDANIKVPKTKKSKFSLGVRSPKLDADIPDAGGNFEGPDMNVDVKGKKGKFKLPKGKGKSKTFDADLKTEMVELETNEPEIHIKSTKVKKPFFGRLHFPDVEFDIKSPKVKASSSASGTMKSSDVDLPSASLKTDIQTPDASLDSPDLKTKGAKVKMSKYSMSSSKLKTSDLDVRDATLEIPEKTMHSPDVSVAGSGINGKRSAKIDIEGKVQSVESAVPSTNVSGGVIDADLGIAEQKGVKGSIGIAGFNVGGQKEDTASGIGLKSDASLSGGIENQEGNLTFPKVKVPKFGIALPRVEPREMREDIGSGELAGGAKVSSQGLEMQKTDVKSSGGKVKVKMPKL-FVKSKSKGGSAADLTVEGEDADATSKGAAKVSKELSLSSGELTSGKLTVEESSGFKVSPKSKSASLDFFKKSRHHSSSVSEEGALASPVSTEGHLQAEAGNVSLDVGDTKVKGKKGKLKFSTIGGFSSKSKGSYEVTD-ESEAMTESASGVAQPSKKSRMSSSSSSDSGTKGSIRLPQLEISVSPKK-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0ACD6B829-1", "uniprot_id": "A0ACD6B829_DANRE", "id": "A0ACD6B829-1", "name": "", "aln": "-----------------------------------------------MALYQRSLSDSLLLEDNVSG------------EYTDLHFLEGEDIVGASDQLELKRNKQKKNEAVDILKLINNDKEFSKHG-------------LKSSRSLENLDMKAPVEVWKDSYDRLYNAKVKRFLKGSQVAKDKRHSKHGSG--------------QETTETLDRKSKVNIATLLQNADRMCLAPSETEFDEKTRSSISHYDP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RDSTGDLMRAKLKTN--------------------------------------------------------------------------------------------TARDFSSLQSKVNLTNVEHEINLRGGTYTDLEKDVGFNT--PDRTFSHGQVSPVMHLTKGHFKTPKAVLNSP-----------------------------DMNMDVPSDNVEKSKFKLPKFSFSGNNNPDIKYDASMK-----------------GSPAEVAAGLNG------------------------------------------------------------------PNIKIDGPKVDYKGLKTDLDMDMPSGKPKAALSGPKMMTS--------------------------------------------------EMDVSTSKFNADCNSPDIKIRG-----QKPGMDVDLPKGNIKAS--------------------------------NLNPPNLDLNASDLNVKAP----------------SGPNLKIKSSDLNFKNSNVN-----------EGINDPGMDLTLPHADLKNP-----------NDFGLTGSKIQTPNYDLKTPEMDLSTPKLKTGLDSTDINIKCQKPDITDTNIDLSKGKITVPNLKTPSHDFNAHDLDIN-------------------------------------------------------------------------------------------------APSGKIKMPKLKIFGNKPEGSSLKIKSSDLNLKTPKIKGGIDTPELNLTQPQTDLKAPNMDIKSPDASKLKMPRPHMNVDANIEQHDLDLSALTPKLNAGIKSPHIDINGPIADIKGPKTDLTLPNMDMPLE------------------------------------------KKKMPTFKMPDFGLSAPNIRTLDADLKTP------QMNLSAPKFKGDFNSP------------------------------------------------------DLSISGHKPDITAPDMNGDFSKGKIKG------------------------------------------------------------------------------------------------------TNLKNPNFDMDTPDFKMNSPSSKLKLQKFGISGSKKKGPDLKIKSPNLNIKSPKMKGGIDT--------------------------------------------------------PDMDPTLP--QVNLKAPNLDLKSPDIDLKDPSG-----KFKMPSLGLPGLKEPHINVDAGIDQPDLN--VSPLTPKLNAGINGPDIDIHGP-----------------------------------------------HADFKGLKTDLKLPDMD----------------------------------------------------------------------------MPSGKKKMPNFKMPSFGLTGPKLKTPDYDLKTP------DMDLFPPKFKADFDSPDINLGHN-------------------------------------------------------IDVTAPNLNVDLPKGKIKGP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DLKTPDLDMNAPNFDINAPSGKMKLPKFGLSG-KPKGPDFKINSPKLNLKSPKIKGGIDT----PDMDMTLPQADFKSPNLDLKSPDIDLNGPSGKLNMAKPKMPSLNLSGLKGSHMNADVNHPDLNLTASTPKLNAGISGPDIDIHGAGLKGP----------QTDLTLPDMDMPPGKMKLP----------------------------------------------------------------NLKFPKFGLSGPKLKTP------------------DYDLKTPDMDLSPPKFKADFDSPDINLG------------------------------------------------------------------HNIDVTAPNLNVDLPKGKIKGPDLKTPDLDMNAPDFDINAPSGKMKLPKFG---------LSGKPKGP--------------DLKINSPKLNLKSPKIKG---GIDAP--------------------DMDVTLPQTDFKSPNLDLKSP-------DIDLNGPSGKFNMAKPKMPSLNMSGLKG--PHMNADVDHPDLN--LTASTPKLNAGMSSPDIDIHGPG--------------------------------------------------------------------------------------------------------------------LKGPKTDLTVP---------DMDMPSGKMKLPNLKFPKFSLSGPKLKTP-------------DYDLKTPEMDLSTPKFKADFDSPDINLG-------------------------------------------------------------------------------------------------------------------HNIDVTAPNMNVDLPKGKIKGPDLKTPDLDMNAPSGKLKLPKFGFFG-------------------------------------KPKGPDFKINSPKLNLKSPKIKG-GIDTPDMDLTLRQADFKS--PNLDLKSPDIDLNGPSGKLNMAKPKMPSLN-----------MSGLKGPHMNADVDHPDLNLTASTPKLSAGISSPDIDIHG--------------------------------------------------------------------------------------------------------------------------------------AGLKGPQTDFTLP--------------------------------------DMDMPSGKMKLPNLKFPKFGLSGPKLKTPDYDLKTPDMDLSPPKFKADFDSPDINLGHN--------------------------------------IDVTAPNMNVDLP-----------------------------------------------------------------------------KGKIKGP-----------------------------------------DLKTPDLDMNAPDFDINAP------------SGKMKLPKFGFFG----------KPKSPDLKINSPKLNLKSP---------KIKGG-------------IDTPDMDLTLR---------------KADFKSPNLDLKSP-------DIDLNGPSGKLNMAKPKMPSLNLSGLKGPQMNADVDHPDLNLTASTPKLNAG-----------------------------MSSPDIDIHGAG------------------------LKGPKMDFTVPD----------------------------------------------------------IDMPSGKMKLPNLKFPKFGLSGPKLKTPDYDLKTPDMDLSPPRFKADFDSPDINLG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------HNIDVTSPNLNVDLPKGKIKGPDLKTPDLDMNAPDFDINASSGKMKLPKFG---------LSGKPKGPDFKINSP--------------KLNLKSPKIKG--------GIDTPDMDVTLPQTDFKS--PNLDLKSPDIDLNGPSGKFNMAKPKMPSLNMSGLKGPHMNADVDHPDLNLT----ASTPKLNAGMSSPDIDIHGPGLKGP----------------------------------------------------------KTDLTVPDMDMPSGKMKLPNLKFPKLGLSGPKLKTPDYDLKTPEMDLSAPKFKADFDSPDLNLDN------NLYVTAPDMNVDLPKGQMKALDLKKPN------------------------------------LDMRMPTGKINMPTLKMPKFGVSGTKIKTPDYDLKTPEMDLSAPEFKADLDTTDINIKGNKPDITGP--------------------------------DMDFDIPKGTFKGP--NLKTPNFNMSAPDLDINAPSGKMKLPKFGKPKG--TNFKMTYPKLTFKNPQNKGGIDIPQTDFKSPNLDADLDHPGLN---------------------------------LSASTPKLNAGINSPDMNVHGFNADHKG---------------------------------------------------MTTDLTPPDINMPSGKMKLPNLKMPKFGLSGPKLKTPEYDLKNP--EIGLSAPKADFDSPEFNIKGQKPEISGP------------------------------------------------------------DMDVNIPKNKFKGPSFKKPNIDMNAP-----------------------------------------DLDINSPSGKLKLPKFSLSGSKPKSPEFKVESQNLNLKTPQIKGGIDT----PDMDLNLLQAKMKTPKLDLKSPDVDLNDPSGKFNMAKPKMP--SLNSPGLKGPHMDADIDHPDLN---LSASSKLNAGVKSPHIDIDGPNADFKVPKTDLTLP-------------------------------------------------------------------------NMDMPSSKKKMPNFKIPDVGFTGPKINMPDYDKPAKIN-------------------------------------------------------------------------------LSAATFKADLDSPDINFRGHKPDITAPD--------------------------------------------------------MNVNVPKSKINVPNFKK----------------------------PNVDLNTPEIDIDAPSAKMKLPKIGLSDLKAEGPDFKMKSPKLKTKSPKINGGIDTPGMDLTLPQTDLKTSNLDFRPPDIDVNGPSGKFNMSKLKMPSLGLSG-------------------------------------LKEPHFDDDIDHPDIRLSSS--------PPKLNAG---INHPDFNIHGPNGDFTLPKTEMPS--------GKIKTSTFKMPDIGFSGQKIKTPDYDLKAPN-----LDLFNSPDLSTRSHKPDF-------------R-------------------------------------------------------------------------------------------------------------------VPDKNVDFPKGKIKATNFKP-------------NLDVYTPELD-----------------NPDFQGLGSNDDFHDYTKMHANNFAIPRGNIKAGKTYDLDPSLRDIRMPNHQKYGTSKFTMQDPYFDLNSG----------------MNISGKAQRPKMTRHLP------DSPDVTMALPTPRPRTSG----------VVPTSSDVYYSEMSGAHRSRDHKRTG------------SNFEIDDSWN---KISVPKLQAPTRTENLPVRNSNMGMSPKQISPHRGG------DARYYRKTQMVPRRHYTTDDICYTYKG--------------------------------------------------------------------------------------------------------MPRRDGRGNEQSDYSRRRTMR-------------------HLQIQAMDLEVPESTLKGSKMNVLKLM-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. : : ...* : :. .* . **::****: :: . : : : : . * * . : . . . :. .:.*.*:*. *:* *:..: .:. .. : *: *:* . : .: .: : . * .: . .. : . : .:. . *: . * : : . ..:. : . * * :. * : * . ::. ..:: ..:: .. . : * .. :* *.* : . ... . * . ::. . :. :.. .: . :** ...:.. : ::.:: . * :: . *: *: .:. * ::::*.:.:::. . *::.: . *::.* .::: :: . :: * *:.. .*. * * : *: *:: *: *:. . : :.::.*: : .:.. ::.:. *.:. *. *:: :. .:: .:****: * * * ..:.:: .. ::. . .:..*::: : .:*..::.: .:. *.::.. : : . : . **::..:*.*::::. * ::.**. .:.:*::.** * * ..**:* : .*:: *.*:. ::*.**.:*::: * : :.* . ** :.::. : .:*::*. ::. *..*:. *:..::.*..*:* ** :. ..* :.: ::::*.**:**.:*. *::* .:* ::::..*.:* . * :.::.*.. ***** : . . ::. :. *. : . *:::. :: *.:::.** . ...* ..*:. *.:: *. : * *:: :*.: .:. ** .:: : *: **. .::. * ::: :* *::::: *:**:**. ::. *.:.:. :.::: *..*:* .** :. . * :.: . .::**.**:**.:*. : ::. *..:::.* ::.**. ::*.. ***.:.: * * . :*. *. :: . *.:: . .:: . :*.. . :::**:*: *: ::: *. :.**::. . .: ::.*. **.*.*.* . :: .:*: . ::.:: *..::*.*.:* *.: * :.: . ::* **. :.*. *.* : *. * **:* :..* *: :. : ::*.* :*:. * :: :: *..* : .* *:* :.. : *.:: .:. *.:: : . .*:::. : *.::: ** :*.*: :: . : *. * *:.*:*.: : * . * : *:. *: : . . *:. *:::: .:*: *::::: *..: *.*.:* *.: *. .: .:.: * . .**: :: **::: : * : *::*:.: :**.. *.:*:. *:::::**..*:: .* *** ***:::.:** . :: .. . .* *.:*:. . :. *: *:.* ::. * ...*:**:.: * * : *: *:: . *:. ..*.. *:::: :*.: .::: :: ...:*** *:* * ::::.*..: . :.*:*::.: * . ..::.:. *.:::. * *:** :. **::: *: :...:.*:::::.* *:.**. ::*.* ::*.:.. * * : :. *. :: . *.:: :* *::*:: * :* **:*: *: :. *. :*:*::*:***.: * * : *: *:. *. ::. . *.. *:::: .:*: *::::: ...*.*** :* *.: .*.:.: . ::* **. :.* * *...*:.* . :* *::* : *::**.:*::*:. *.:*:. *:::::**..*.: .* *:*.: .. * . *.. . ::. * **::. :. * :*::.* . :: ** . :*:*::*:**:.: * * : *: *:. *: *:.. . *.. *:::::. . .. *.: . ** .* *:: . *:. ::**.:*****.. * * : *: ::. *: *:.. . *:. .:::*.* . .:.** *:.. :* :* * ::: * *:.. . :*:*:. ** . * *.: .. *: . :. *. *:. *::: : . :: :..* **::. :: *.:::.. : * . :: ** . :*:*::*****.: * * : *: *:. * :: :..*. *:. *:..: * . ::.** .:::: *:.*:***.:: * :..* ::**: ..**:* *** :.. *::.: . ::*:* *::**.:* : *:: ...:* *::.:.: *.**:. .* * * :..* :. *.:* ::. *.:: : .*::..:*....:* *: * . *. .: * *:: *..* * .:*.:* :..**:.*** * * :: ...:.::. *: :::. : :. *: ::. *. :::*:.* *.**:. *:::::.*. *:* **: ..: ..* :.: . .:. *. *::* .* . :. : :* . :*:: * :*.:**..*:. ..:.** :. . . .:: ***. **:. : *. ::: *. *. : .:: * . . : .: :** .:. . .:. . .:. : *:. ** *:: ..*:*:..* :..: *::. . .::* : :. : .: . . . *. . : . . ::. .: . :*:.* : .: * .:. : : . . : *. . : :. .:.. : . :..*::: * . . . : . : . . . * . . . . : . * :: :. *: .: .:.* ", "identical_positions": 572, "similar_positions": 1392, "identity": "8.08%" }, { "cls_id": "homologset.agr.MGI:1316649", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CI15-1", "uniprot_id": "SPHK1_MOUSE", "id": "Q8CI15-1", "name": "Sphingosine kinase 1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEPVECPRGLLPRP------------------CRVLVLLNPQGGKGKALQLFQSRVQPFLEEAEITFKLILTERKNHARELVCAEE--LGHWDALAVMSGDGLMHEVVNGLMERPDWETAIQKP-LCSLPGGSGNALAASVNHYAGYEQVTNEDLLINCTLLLCRRRLSPMNLLSLHTASGLR---LYSVLSLSWGFVADVDLESEKYRRLGEIRFTVGTFFRLASLRIYQGQLAYLPVGTVASKRPAS-TLVQKGP---------------------------------------------------------------------------------------------------VDTHLVPLEEPVP-SHWTVVPEQ--DFVLVLVLLHTHLSSELFAAPMGRCEAGVMHLFYVRAGVSRAALLRLFLAMQKGKHMELDCP-YLVHVPVVAFRLEPRSQRGVFSVDGELMVCEAVQGQVHPNYLWMVCGSRDAPSGRDSRRGPPPEEP-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q91V26-1", "uniprot_id": "SPHK1_RAT", "id": "Q91V26-1", "name": "Sphingosine kinase 1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQPADCPRGLLPRP------------------CRVLVLLNPRGGKGKALKLFQSRVRPLLEEAEVSFKLMLTERQNHARELVCAEE--LGHWDALAVMSGDGLMHEVVNGLMERPDWESAIQKP-LCSLPGGSGNALAASLNYYAGHEQVTNEDLLINCTLLLCCRQLSPMNLLSLHTASGRQ---LYSVLSLSWGFVADVDLESEKYRSLGEIRFTVGTFFRLASLRIYQGQLAYLPVGKAASKIPAS-SLAQKGP---------------------------------------------------------------------------------------------------ANTYLVPLEEPVP-PHWTVVPEQ--DFVLVLVLLHTHLSTEMFAAPMGRCEAGVMHLFYIRAGVSRAMLVRLFLAMQKGKHMDLDCP-YLVHVPVVAFRLEPRNQRGVFSVDGELMVCEAVQGQVHPNYLWMVSGSSDSPSGRDSQRRPPPEEPI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NYA1-1", "uniprot_id": "SPHK1_HUMAN", "id": "Q9NYA1-1", "name": "Sphingosine kinase 1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDPAGGPRGVLPRP------------------CRVLVLLNPRGGKGKALQLFRSHVQPLLAEAEISFTLMLTERRNHARELVRSEE--LGRWDALVVMSGDGLMHEVVNGLMERPDWETAIQKP-LCSLPAGSGNALAASLNHYAGYEQVTNEDLLTNCTLLLCRRLLSPMNLLSLHTASGLR---LFSVLSLAWGFIADVDLESEKYRRLGEMRFTLGTFLRLAALRTYRGRLAYLPVGRVGSKTPASPVVVQQGP---------------------------------------------------------------------------------------------------VDAHLVPLEEPVP-SHWTVVPDE--DFVLVLALLHSHLGSEMFAAPMGRCAAGVMHLFYVRAGVSRAMLLRLFLAMEKGRHMEYECP-YLVYVPVVAFRLEPKDGKGVFAVDGELMVSEAVQGQVHPNYFWMVSGCVEPPPSWKPQQMPPPEEPL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VYY8-1", "uniprot_id": "Q9VYY8_DROME", "id": "Q9VYY8-1", "name": "sphingosine kinase", "aln": "-------------------MTANTGTSGENLMGNGGKTHEPSTPTSDTEVAS-------------------------------------GTPTELSEIFFVDNSRRKQSIKIQVKLCPEGVYLRRETEEDDHINEQLIRIDDIIGSRYGRRLKKR--ARGGLNSCR--NPNVPGQEADSEPD---------------------SDNSAYLYIYAYLKKEKPLR----RVQTLRILRFRSSNDYGVNLQTAEMWHHTIRKHKRGN-----GSSSPADCGKQLLILLNPKSGSGKGRELFQKQVAPLLTEAEVQYDLQITTHPQYAKEFVRTRRDLLTRYSGIVVASGDGLFYEVLNGLMERMDWRRACRELPLGIIPCGSGNGLAKSVAHHCNEPYEP--KPILHATLTCMAGKSTPMDVVRVELATRDKHFVMYSFLSVGWGLIADIDIESERLRSIGAQRFTLWAIKRLIGLRSYKGRVSYLLGKGKKEPPVEAARELPAESTAAGIRSSLPLNAGEFHDLPEEEEGEAVLDGEQFADAISLDRSV---YRQHADSWHSAMSRRTAYYSLGGPSMRSNRSRMSISQRIEAANAEFAER--VPTGTIPPLQMPLLSSDGWICEDG--DFVMVHAAYTTHLSSDVFFAPESRLDDGLIYLVIIRRGVSRHQLLNFMLNLNAGTHLPIGEDPFIKVVPCRAFRIEPSSSDGILVVDGERVEYGPIQAEVMPGLINVMTTSGQ-----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VZW0-1", "uniprot_id": "Q9VZW0_DROME", "id": "Q9VZW0-1", "name": "sphingosine kinase", "aln": "--------------------------MSESLDKTTSPSSASSRATPPGTQDA-------------------------------------DEGHDVSDTFYTSQ-RKKGSHVFRVRLDATGFTLQRESPGGSIVKEQHVRISDIVGARCMRPKKSRRLAMSGACACSSGNPNSPAISASGDHHRPATTPSKCSTNSRDNIPSDGGDVSAFLYVFAYVLKKRSLRSELHRERTVLTLRFRSFDTFEDNMREADRWYRSLRWQLHRTLEEIFVAPTVDERRRRVLVLLNPKSGSGDAREVFNMHVTPVLNEAEVPYDLYVTKHSNFAIEFLSTR--CLDAWCCVVAVGGDGLFHEIVNGLLQRQDWAHVLPHLALGIIPCGSGNGLARSIAHCYNEPYFS--KPVLGAALTVISGRSSPMDVVRVQLQSRS----LYSFLSIGWGLISDVDIESERIRMLGYQRFTVWTLYRLVNLRTYNGRISYLLT-DHEVSSTHSATGYAAQRRMQSSRSCN-THIDMLNGPAPIYHSSAEYLPQEFADVISLETSINQSFRSRCDSWLSGGSRRSFYYSIS-ESIYHSLADESEFAGLAAASLENRQQNYGPASELPDLNEPLSEDQGWLVEEG--EFVMMHAVYQTHLGIDCHFAPKAQLNDGTIYLILIRAGISRPHLLSFLYNMSSGTHLPESHDDHVKVLPVRAFRLEPYDNHGIITVDGERVEFGPLQAEVLPGIARVMVPK-------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06147-1", "uniprot_id": "LCB5_YEAST", "id": "Q06147-1", "name": "Sphingoid long chain base kinase 5", "aln": "MTLKPSKRRKGRSRHSRKKQITSAILTEEGIMIKAKPSSPYTYANRMADKRSRSSIDNISRTSFQSNISRTSFQSNSDNNSIFETASLISCVTCLSDTDTIDRSETSTTDTSKDDLSAN-PKLHYPSVNGQLPANTVIPYGRILDARYIEKEPLHYYDANSSPSSPLSSSMSNISEKCDLDELESSQKKE---RKGNSLSRGSNSSSSLLTSR--SPFTKLVEVIFARPRRHDVVPKRVSLYIDYKPHSSSHLKEEDDL----VEEILKRSYKNTRRNKSIFVIINPFGGKGKAKKLFMTKAKPLLLASRCSIEVVYTKYPGHAIEIAREMD--IDKYDTIACASGDGIPHEVINGLYQRPDHVKAFNNIAITEIPCGSGNAMSVSCHWTNNPSYST---------LCLIKSIETRIDLMCCSQPSYAREHPKLSFLSQTYGLIAETDINTEFIRWMGPARFELGVAFNIIQKKKYPCEIYVKYAAKSKNELKNHYLEHK--NKGSLEFQHITMNKDNEDCDNYNYENEYETENEDEDEDADADDED------------------------------------SHLISRDLADSSADQIKEEDFKIKYPLDEGIPSDWERLDPNISNNLGIFYTGKMPYVAADTKFFPAALPSDGTMDMVITDARTSLTRMAPILLGLDKGSHVLQPEVLHSKIL---AYKIIPKLGNGLFSVDGEKFPLEPLQVEIMPRLCKTLLRNGRYVDTDFDSM--------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q12246-1", "uniprot_id": "LCB4_YEAST", "id": "Q12246-1", "name": "Sphingoid long chain base kinase 4", "aln": "MVVQKKLR---------------AILTDEGVLIKSQ-------SHHMFNKHG-------------------QLRSG-------DSLSLLSCLSCLDDGTLSSDGGSFDEDDSLELLPLN-TTIPF---NRILNAKYVNVGQKGFNNGKISSNPFQTENLSSSSENDDVENHSLSNDKAPVSESQSFPKKDKWDTKTNTVKVSPDDSQDNSPSLGIKDNQQLIELTFAVPKGHDVIPQKLTLLIDHVSRKSRANTGEENISSGTVEEILEKSYENSKRNRSILVIINPHGGKGTAKNLFLTKARPILVESGCKIEIAYTKYARHAIDIAKDLD--ISKYDTIACASGDGIPYEVINGLYRRPDRVDAFNKLAVTQLPCGSGNAMSISCHWTNNPSYAA---------LCLVKSIETRIDLMCCSQPSYMNEWPRLSFLSQTYGVIAESDINTEFIRWMGPVRFNLGVAFNIIQGKKYPCEVFVKYAAKSKKELKVHFLENKDKNKGCLTFEPNPSPNSSPDLLSKNNINNSTKD-----------------------------------------------------------ELSPNFLNEDNFKLKYPMTEPVPRDWEKMDSELTDNLTIFYTGKMPYIAKDTKFFPAALPADGTIDLVITDARIPVTRMTPILLSLDKGSHVLEPEVIHSKIL---AYKIIPKVESGLFSVDGEKFPLEPLQVEIMPMLCKTLLRNGRYIDTEFESM--------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :::::** .*.* . ::* :. *.* : : * .* :: : : :. .***: :*::*** .* * . . : :* ****.:: * . . * : :::: : *.** :*.::: *:::* * :* ** : . .: : * .: : : : : :: :. . .::. : * . * : :. . : :: :. * *: . : *::: * *:: **** . .:* :: * : ", "identical_positions": 49, "similar_positions": 98, "identity": "6.47%" }, { "cls_id": "homologset.agr.MGI:1316652", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AYB9-1", "uniprot_id": "Q6AYB9_RAT", "id": "Q6AYB9-1", "name": "Protein arginine N-methyltransferase 2", "aln": "MEAPAEDPSHESQVTPAPVRKSHGLTIVRRRSASSQEEDPVDYGCEMQLLQDGAQLQLQLQPEEFVAIADYTATDETQLSFLRGEKILILRQTTADWWWGERAGCCGYIPANHLGKQVEEYDPEDTWQDEEYFDSYGTLKLHLEMLADQPRTTKYHSVILQNKESLKDKVILDVGCGTGIISLFCAHHARPKAVYAVEASDMAQHTGQLVLQNGFADTITVFQQKVEDVVLPEKVDVLVSEWMGTCLLFEFMIESILYARDAWLKEDGIIWPTTAALHLVPCSAEKDYHSKVLFWDNAYEFNLSALKSLAIKEFFSRPKSNHILKPEDCLSEPCTILQLDMRTVQVSDLETMRGELRFDIQKAGTLHGFTAWFSVHFQSLEEGQPQQVLSTGPLHPTTHWKQTLFMMDDPVPVHTGDVVTGSVVLQRNPVWRRHMSVCLSWVVTSAVDPTSQRAGEKVFPIWR-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R144-1", "uniprot_id": "ANM2_MOUSE", "id": "Q9R144-1", "name": "Protein arginine N-methyltransferase 2", "aln": "MEAPGEGPCSESQVIPV------------------LEEDPVDYGCEMQLLQDGAQLQLQLQPEEFVAIADYTATDETQLSFLRGEKILILRQTTADWWWGERAGCCGYIPANHLGKQLEEYDPEDTWQDEEYFDSYGTLKLHLEMLADQPRTTKYHSVILQNKESLKDKVILDVGCGTGIISLFCAHHARPKAVYAVEASDMAQHTSQLVLQNGFADTITVFQQKVEDVVLPEKVDVLVSEWMGTCLLFEFMIESILYARDTWLKGDGIIWPTTAALHLVPCSAEKDYHSKVLFWDNAYEFNLSALKSLAIKEFFSRPKSNHILKPEDCLSEPCTILQLDMRTVQVPDLETMRGELRFDIQKAGTLHGFTAWFSVYFQSLEEGQPQQVVSTGPLHPTTHWKQTLFMMDDPVPVHTGDVVHGFCCVTKK-SGMEKAHVCLSELG-CHVRTRSHVSTELETGSFRSGGDS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P55345-1", "uniprot_id": "ANM2_HUMAN", "id": "P55345-1", "name": "Protein arginine N-methyltransferase 2", "aln": "MATSGDCPRSES-----------------------QGEEPAEC-SEAGLLQEG------VQPEEFVAIADYAATDETQLSFLRGEKILILRQTTADWWWGERAGCCGYIPANHVGKHVDEYDPEDTWQDEEYFGSYGTLKLHLEMLADQPRTTKYHSVILQNKESLTDKVILDVGCGTGIISLFCAHYARPRAVYAVEASEMAQHTGQLVLQNGFADIITVYQQKVEDVVLPEKVDVLVSEWMGTCLLFEFMIESILYARDAWLKEDGVIWPTMAALHLVPCSADKDYRSKVLFWDNAYEFNLSALKSLAVKEFFSKPKYNHILKPEDCLSEPCTILQLDMRTVQISDLETLRGELRFDIRKAGTLHGFTAWFSVHFQSLQEGQPPQVLSTGPFHPTTHWKQTLFMMDDPVPVHTGDVVTGSVVLQRNPVWRRHMSVALSWAVTSRQDPTSQKVGEKVFPIWR-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QDD1-1", "uniprot_id": "F1QDD1_DANRE", "id": "F1QDD1-1", "name": "Protein arginine N-methyltransferase 2", "aln": "MIESESRDCNEG--------------------------------------------------EEYVGLVDFVAEGDEQLSFSVGDKLLVHDRSSDVWWWAEMQGRFGYVPSSYLHQRTEDM--EDAWQDDEYFGNYGTLRLHLEMLSDKPRTETYRQVILSNSAALREKVVLDLGCGTGVISLFCALLAKPAGVYAVEASSMAEHTEELVKQNGCDGVVTVFQERAENLTLPTKVDVLVSEWMGNCLLFEYMLESVLLARDRWLKKGGMMWPSSACLTIVPCQAFSDYRQKVEFWENPYGLNFSYLQSLAQKEFLSKPKFSHHLQPEDCLSTPADVITLDMVTIQVSDLERLKGEFTFTVEKSGMFHGFTVWFSAHFQSLEDG-PSIELNTGPYSEITHWKQTLFMLDAPVSVEEGDIIAGSIRLQRNPIWRRHLSITFLWNINSTEVST---VKTKCFPMWR-----", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . . *. **:*.:.*:.* .: **** *:*:*: ::: ***.* * **:*:.:: :: :: **:***:***..****:******:*:*** .*:.***.*. :* :**:**:*****:****** *:* .*******.**:** :** *** . :**:*::.*::.** ***********.*****:*:**:* *** *** .*::**: *.* :***.* .**:.** **:*.* :*:* *:*** ***:*:** .* *:****** *. :: *** *:*:.*** ::**: * :.*:* :****.***.:****::* * :.*** *********:* **.*. **:: * : :: .: : : . . :* ", "identical_positions": 199, "similar_positions": 116, "identity": "42.52%" }, { "cls_id": "homologset.agr.MGI:1316658", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q61462-1", "uniprot_id": "CY24A_MOUSE", "id": "Q61462-1", "name": "Cytochrome b-245 light chain", "aln": "MGQIEWAMWANEQALASGLILITGGIVATAGRFTQWYFGAYSIAAGVLICLLEYPRGKRKKGSTMERCGQKYLTSVVKLFGPLTRNYYVRAALHFLLSVPAGFLLATILGTVCLAIASVIYLLAAIRGEQWTPIEPKPKERPQVGGTIKQPPTNPPPRPPAEVRKKPSEGEEEAASAG---GPQVNPMPVTDEVV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q62737-1", "uniprot_id": "CY24A_RAT", "id": "Q62737-1", "name": "Cytochrome b-245 light chain", "aln": "MGQIEWAMWANEQALASGLILITGGIVATAGRFTQWYFGAYSIVAGVLICLLEYPRGKRKKGSTMERCGQKYLTAVVKLFGPLTRNYYVRAVLHLLLSVPAGFLLATILGTVCLAIASVIYLLAAIRGEQWTPIEPKPKERPQVGGTIKQPPTNPPPRPPAEVRKKPSEAEEEAASAG---GPQVNPIPVTDEVV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P13498-1", "uniprot_id": "CY24A_HUMAN", "id": "P13498-1", "name": "Cytochrome b-245 light chain", "aln": "MGQIEWAMWANEQALASGLILITGGIVATAGRFTQWYFGAYSIVAGVFVCLLEYPRGKRKKGSTMERWGQKYMTAVVKLFGPFTRNYYVRAVLHLLLSVPAGFLLATILGTACLAIASGIYLLAAVRGEQWTPIEPKPRERPQIGGTIKQPPSNPPPRPPAEARKKPSEEEAAVAAGGPPGGPQVNPIPVTDEVV", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*******************************************.***::****************** ****:*:*******:********.**:****************.****** ******:************:****:********:*********.****** * .*:.* ******:*******", "identical_positions": 169, "similar_positions": 18, "identity": "86.67%" }, { "cls_id": "homologset.agr.MGI:1316659", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q02734-1", "uniprot_id": "SIAT6_RAT", "id": "Q02734-1", "name": "CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase", "aln": "MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWE-DSNSLILSLDSAGQTLGTEYDRLGFLLKLDSKLPAELATKYANFSEGACKPGYASAMMTAIFPRFSKPAPMFLDDSFRKWARIREFVPPFGIKGQDNLIKAILSVTKEYRLTPALDSLHCRRCIIVGNGGVLANKSLGSRIDDYDIVIRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSAS--------------------------DGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALDGCDEVAVAGFGYDMNTPNAPLHYYETVRMAAIKESWTHNIQREKEFLRKLVKARVITDLSSGI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97325-1", "uniprot_id": "SIAT6_MOUSE", "id": "P97325-1", "name": "CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase", "aln": "MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWE-DSNSLLLSLDSAGQTLGTEYDRLGFLLKLDSKLPAELATKYANFSEGACKPGYASAMMTAIFPRFSKPAPMFLDDSFRKWARIREFVPPFGIKGQDNLIKAILSVTKEYRLTPALDSLHCRRCIIVGNGGVLANKSLGSRIDDYDIVIRLNSAPVKGFERDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSAS--------------------------DGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMNTPNAPLHYYETVRMAAIKESWTHNIQREKEFLRKLVKARVITDLSSGI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q11203-1", "uniprot_id": "SIAT6_HUMAN", "id": "Q11203-1", "name": "CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase", "aln": "MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSNSVVLSFDSAGQTLGSEYDRLGFLLNLDSKLPAELATKYANFSEGACKPGYASALMTAIFPRFSKPAPMFLDDSFRKWARIREFVPPFGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSAS--------------------------DGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMAAIKESWTHNIQREKEFLRKLVKARVITDLSSGI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PLX6-1", "uniprot_id": "A0A8M9PLX6_DANRE", "id": "A0A8M9PLX6-1", "name": "CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase", "aln": "MFRMKSMRSFMFLICPVMVLVFFYYSSGRLQLKNSVQKSQADLDSLLSVGRVVASVYDKQGFLLKLDKKLPLELQYKYGNLSKGECKQGFAQAKMTLIYPKFSKPAPMFLDPNYKRLSKISSYPPPFGVRTQERIIDNILAATRSYSLGPELDSIPCKKCIIIGNGGILFNKSLGTKIDQYDVVVRLNEAPVAGFEKDVGSKTTMRITYPEGAIQRAERYEKSSLFVLSAFKSNDFKWLRHMVYKDRLTPGGPLTVNQIQTDAFETCGPEYSLSWRMDGFWKSVARVVPRAPQDMRILNPYFIQEASFRLIGLPHNNGLMGRGNIPTLGTVAITMALHNCDEVAVAGFGYDMNTPHAPLHYYEKLRMSAIKESWTHNISREKEFLRKLVKAGVIEDLTHGI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : :*.::: :* .:** *:***: :*:* : .*:: : *: *.*:.:.: **: ****:**.*** ** **.*:*:* ** *:*.* ** *:*:********** .::: ::* .: ****:: *:.:*. **:.*:.* * * ***: *::***:****:* *****::**:**:*:***.*** ***:*******:********:**.*:**:.*****:.** :*****:::***:*::.. ******** **: * ::***********:* *****.**************:**:****..*************.**:*******.:**:**********.************ ** **: **", "identical_positions": 232, "similar_positions": 98, "identity": "57.86%" }, { "cls_id": "homologset.agr.MGI:1316660", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q71RJ2-1", "uniprot_id": "CCG2_RAT", "id": "Q71RJ2-1", "name": "Voltage-dependent calcium channel gamma-2 subunit", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGLFDRGVQMLLTTVGAFAAFSLMTIAVGTDYWLYSRGVCKTKSVSENETSKKNEE-----VMTHSGLWRTCCLEGNFKG---LCKQIDHFPED--ADYEADTAEYFLRAVRASSIFPILSVILLFMGGLCIAASEFYKTRHNIILSAGIFFVSAGLSNIIGIIVYISANAGDP-------SKSDSKKNSYSYGWSFYFGALSFIIAEMVGVLAVHMFI-------------------------------DRHKQLR---ATARATD-------------------------------------------------------------------------------------------YLQASAITRIPSYRYRYQRRSRSSSRSTEPSHSRDASPVGVKGFNTLPS------------------TEISMYTLSR---------------------DPLKAATTPTATYNSDRDNSFLQVHNCIQKDSKDSLHANTANRRTTPV----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88602-1", "uniprot_id": "CCG2_MOUSE", "id": "O88602-1", "name": "Voltage-dependent calcium channel gamma-2 subunit", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGLFDRGVQMLLTTVGAFAAFSLMTIAVGTDYWLYSRGVCKTKSVSENETSKKNEE-----VMTHSGLWRTCCLEGNFKG---LCKQIDHFPED--ADYEADTAEYFLRAVRASSIFPILSVILLFMGGLCIAASEFYKTRHNIILSAGIFFVSAGLSNIIGIIVYISANAGDP-------SKSDSKKNSYSYGWSFYFGALSFIIAEMVGVLAVHMFI-------------------------------DRHKQLR---ATARATD-------------------------------------------------------------------------------------------YLQASAITRIPSYRYRYQRRSRSSSRSTEPSHSRDASPVGVKGFNTLPS------------------TEISMYTLSR---------------------DPLKAATTPTATYNSDRDNSFLQVHNCIQKDSKDSLHANTANRRTTPV----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y698-1", "uniprot_id": "CCG2_HUMAN", "id": "Q9Y698-1", "name": "Voltage-dependent calcium channel gamma-2 subunit", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGLFDRGVQMLLTTVGAFAAFSLMTIAVGTDYWLYSRGVCKTKSVSENETSKKNEE-----VMTHSGLWRTCCLEGNFKG---LCKQIDHFPED--ADYEADTAEYFLRAVRASSIFPILSVILLFMGGLCIAASEFYKTRHNIILSAGIFFVSAGLSNIIGIIVYISANAGDP-------SKSDSKKNSYSYGWSFYFGALSFIIAEMVGVLAVHMFI-------------------------------DRHKQLR---ATARATD-------------------------------------------------------------------------------------------YLQASAITRIPSYRYRYQRRSRSSSRSTEPSHSRDASPVGIKGFNTLPS------------------TEISMYTLSR---------------------DPLKAATTPTATYNSDRDNSFLQVHNCIQKENKDSLHSNTANRRTTPV----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4INZ4-1", "uniprot_id": "A0A0R4INZ4_DANRE", "id": "A0A0R4INZ4-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGVFERGVQMLLTTVGAFAAFSLMTIAVGTDYWLYSRGVCKIKSTNENETSKKNEE-----VMTHSGLWRTCCLEGNFKG---MCKQIDHFPED--ADYEADASEYFLRAVRASSIFPILSVILLFMGGLCVAASEFYKSRHNIILSAGIFFVSAGLSNIIGIIVYISANAGDP-------SKSDSKKNSYSYGWSFYFGALSFIMAEMVGVLAVHMFI-------------------------------DRHRELRVAQARVRGAD-------------------------------------------------------------------------------------------YLQGAAITRIPSYRYRYRRSSRSSSRSTDPSHSRDTSPVGLKGFAALPS------------------TDISMYTLSRGG------------------GDTLKTPHGTPPMYNSDREAEFLQVHNCIPKDSKD--------RRTTPV----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q2MGK8-1", "uniprot_id": "Q2MGK8_DROME", "id": "Q2MGK8-1", "name": "", "aln": "MRDYPSVPNVFRVASTHSINSENPYNNIRPANVICNTTERPPIAIHQLTTSASIEHSHPSQQAQHQQQQLLHHQQQHHHQQHSPYATLPRGQRLAPQQHQQAGVINTISGSIPATGFSSLAGSFSDLQLNNIGNHSSNSRSNHNSISNNRRQQQQQQQQQQQRLVPHLSRHQPAIEVQQTQQHQQTQQQHVQRQQQQERLASGGAGATDPQGGISNMTTVNGGYLWLITPVAASISVAIVIAALAGPQWLFTEEKLPNANYNGTANFKALDDGAYITKYTKSSLWILCTTLPGLDADSYNCVKIDYFSNEGYQPDPHDSTAAIPYTVTKSCPIFLAAGVFLVISFIVFLIPTCSHQNNLYYFSAGILFIVSGLVMLIGLIAYISILKAEIGSKLRPRSTLQPALIKVSYGQSFFLFVFGFIVTEFVGVLNIFLFINLQEVSYYSRLPCFSVANIHAKLKEGQHPLSDSYKRYKQPGITTASQEGLSSAGQGQQGHQSHHPTHQPHPTAQPPHGILRSGNSRLHQVYDAGRGHPGMTGQIGHSGQTQTLPGACRKHPNAGSNLNLYLHNDLERRFYFEKPAVSKCNLHSRSFAKSLNELCTDTSVSSTHVPAPLLPSAADPLPAPALFADLPQEFPLTRSVSTATEIYPASSSAPAPPSAQMKRKQQRNMATNTNTKISNNPPSSNSQMADQSRLCGLKRGLRKTKDELFQEFCRRAGMRSKPKNIYYISGGDEAEEEEQEDQAKREEVPDDPHRDDDDDADGDDHGFRQFNRMEEEHLYVVGDHAQLVVPRRTSMCVDSMGQPLRRLNSNLSLHTDLSFPGTGGYPGMRMSLPQPADLGQSRTLPRCFLRQSSDSLASQGYPLGSSQQRFSQLMLNQQQNRFVSSTLTLPQVVAPKSQVQWPTAIPSSPSNYSNGYQQHPQPIYPAPTSGSGAPGTTASVSGPPKFQRGYAFDDQQRRSSFVSDAFDLDEIERERRRSHASLFGMGQVRDPYDLINGTAV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .: * *:*.*.* :.::: *:. **::. . . . . * :: *:*.** * .:.. * :**:*.:: *:: : :* *. : : : ::*.:. : . . : .: :****:*: :** :**:*.*** .: *. :. . *** **:: .:.**::*:**** :.:** * ::. : . . : *:: .*::: : : : .. . .*. * :: .:*: .. .**: * .:*. * * . ... .. : . * : :..** * ", "identical_positions": 67, "similar_positions": 120, "identity": "6.7%" }, { "cls_id": "homologset.agr.MGI:1316664", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A741-1", "uniprot_id": "D4A741_RAT", "id": "D4A741-1", "name": "", "aln": "-----MMFSWIFIFWLLQILKFVS-AIVFNISRCYYIITEEF------HHEGDIVIGAFFPLHTFYTGKKMPDPTLPYQYLDNYIQYNFRNYQYILALLFAIEEINGNPNLLPNISLGFDFYNVRFTEKETLMNAVIWLTAHVQRKVLPNYNCKKKKFSAALTG-TSWTTSAQIGTLLQLFKFPQITFGPYDPLLSDHGQYSSLYQMAPKDTSLSLAIVSLMVYFRWSWVGLILPDDHKGNKILSDYREEMERQRVCIAFVKMIPATWTSYFPRFWENMNETN---VIIIHGDIDSLESLLRNIGQRLLTRNVWVMNIER--HVTEFSDYFMLDSFHGSLIFKHNYREKFEFTKFIQTVNPNRYPEDIYLPKLWNLLFKCSFSDRNCQVLDNCQTNASLDILPS---HIFDVAMSEESISIYNGVYAVAHSLHDMRLHQVQMRPYENGE-----GMIFIPWQLNTFLKDLEVRDNRSLNWIQTIDAEYDILNLWNLPKGLGLKVKIGSFSANAPKGQQLSLSEQIIQWPEIFSKVPQSVCSESCGPGFRKVTLEGKPICCYKCTPCAENEISNETDSDQCVRCPESHYPNTEKSNCYQKTSSFLAFEEPLGMALASIALCLSALTAFVIGIFVKYRDTPIVKANNQALSYILLITLKFCFLCSLNFIGQPNTAACILQQTTFGVAFTVALATVLAKAITVVLAFKVSFPG--RMVRWLMISRGPYYIVPICTLIQLLLCGIWMTMSPPFIDQDPHTEHGHIIILCNKGSSLAFHAVLGYLCLLALGSYTMAFLSRNLPDTFNESKFLSLSMLVFFCVWVTFLPVYYSTKGKVMVAMEVFSILASSTALLAFIFGPKCYIILLRPDKNSFNHVRKK--AHFRRKNSPKI--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9PZJ7-1", "uniprot_id": "E9PZJ7_MOUSE", "id": "E9PZJ7-1", "name": "", "aln": "------MFSWIFIFLLLQIPKFVSSDLKFNVNRCYFEITEEF------HHEGDVMIGAFFPVHTFYTEKKRPHSTIPYQYLDGYIQYNFKNYQYILALLFAIEEINGNPNLLPNISLGFDFYNVRFTEKETLMNTVIWLTAHVQRKVLPNYNCKKSNFTAAITG-TSWITSAQIGTLLQLFKFPQITFGPYDPFLSDRGQYPSLYQMAPKDTSLSLAIVSLMVHFRWSWVGLILPDDHKGNKILSDFRKEMERKRICTAFVKMIPATWTSSFVKFWENMDDTN---IIIIYGDIDSLEGLMRNIGQRLLTWHVWVMNIEP--HIIEYDNYFMLDSFHGSLIFKHNYRENFEFTKFIRTVNPKKYPEDIYLPKMWYLFFMCSFSDINCQVLDSCQTNASLDMLPS---QIFDVVMSEESTSIYNAVYAVAHSLHEMRLQQLQTQPCENEE-----GMEFFPWQLNTFLKDIEVRVN-SLDWRQRIDAEYDILNLWNLPKGLGLKVKIGNFYANAPQGQQLSLSEQMIQWPEIFSEIPQSVCSESCGPGFRKVTLENKAICCYNCTPCADNEISNETDVDQCVKCPESHYANTEKSNCYQKSVSFLGYEDPLGMALASIALCLSALTAFVIGIFVKHKDTPIVKANNQALSYTLLITLKFCFLCSLNFIGQPNTVACILQQTTFAVAFTMALATVLAKAITVVLAFKVSFPG--RMVRWLMISRGPNYIIPICTLIQLLLCGIWMAISPPYIDQDAHIEHGHIIILCNKGSAVAFHSVLGYLCFLALGSYTMAFLSRNLPDTFNESKFISLSMLVFFCVWITFLPVYHSTKGKVMVAMEVFSILASSTALLAFIFGPKCYIILLRPEKNSFHHIREKRTTHSRRKIFFLKYS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1QSW4-1", "uniprot_id": "F1QSW4_DANRE", "id": "F1QSW4-1", "name": "", "aln": "MSIHVLSWLTLSVPVLLLWPVCGSGTEVTPLETCVYLITPQYSDELGTYQDGDVIIGGLINLHNLAATPDLSFTRKP--GLAQCLEFQERTYRWFQAIVFTVEEINQHPSLLPGVKLGYHIMDSCSRYPHSLTAAMSMISGGNK-------TCGPTKPAKLLIGDSSSTQSILLSTTLVPLKIPMISYLAGCPCLSDRQKYPNFFRTIPSDFYQARTMVQIAKRFGWTWIGAVIADSDNGHGTLQALEEEIKGTGICLAFYHTLYRERLQKDVAFAARTVQASSARVILVLAWYTDVEAFLLELMRRNVTDRLFLASEIWSTSYNIMANPQLYTISKGTLGVALRSAPIPGFSAHLQQLHPSRYPEDKFLRTLWENTFGCSPTISSSKIIQNSLPPCSGRESLEGHIEFIDTSHLTVSYNIYLAVYAAAHALHSLLECNSQNHTDSKIKPKCSSPDNITPAQLLQHVKDVQYTTQLGEEFYFLEGGIPPVYDLVNWQIAP--DGSLQYAFIGHVDGNQLSINDSAITWPGDSGKVPISVCTSECPPGTRKAIKKGLPVCCFDCLPCTEGEISNSTGSIKCYRCPKEFWSNSYKNECVARETEFLSVKETMGITLMSVAVSGAVMTTTVAVIFLYHRNTPIVKANNSELSFLLLLSLKLCFLCALVFVGQPSLWSCRIQQAAFGISFVLCISCILVKTFVVLIAFHSTRPESSALIKWFGLGK-QRGIVLVFTCVQVVICAIWLCVSPPLPYQNFGMHRSKVILECTIGSVVGFTCVLGYIGFLATVCFLLAFFARKLPDNFNEAKYITFSMLIFCAVWVAFVPAYVSSPGKYSVVVEVFAILASSFGLLFCIFVPKCYIILLKPENNTKKFLMGKE--------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 237, "similar_positions": 324, "identity": "26.63%" }, { "cls_id": "homologset.agr.MGI:1316665", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A741-1", "uniprot_id": "D4A741_RAT", "id": "D4A741-1", "name": "", "aln": "---MMFSWIFIFWLLQILKFVS---AIVFNISRCYYIITEEF------HHEGDIVIGAFFPLHTFYTGKKMPDPTLPYQYLDNYIQYNFRNYQYILALLFAIEEINGNPNLLPNISLGFDFYNVRFTEKETLMNAVIWLTAHVQRKVLPNYNCKKKKFSAALTG-TSWTTSAQIGTLLQLFKFPQITFGPYDPLLSDHGQYSSLYQMAPKDTSLSLAIVSLMVYFRWSWVGLILPDDHKGNKILSDYREEMERQRVCIAFVKMIPATWTSYFPRFWENMNETN---VIIIHGDIDSLESLLRNIGQRLLTRNVWVMNIER--HVTEFSDYFMLDSFHGSLIFKHNYREKFEFTKFIQTVNPNRYPEDIYLPKLWNLLFKCSFSDRNCQVLDN----CQTNASLDILPSHIFDVAMSEESISIYNGVYAVAHSLHDMRLHQVQMRPYENGE-----GMIFIPWQLNTFLKDLEVRDNR---SLNWIQTIDAEYDILNLWNLPKGLGLKVKIGSFSANAPKGQQLSLSEQIIQWPEIFSKVPQSVCSESCGPGFRKVTLEGKPICCYKCTPCAENEISNETDSDQCVRCPESHYPNTEKSNCYQKTSSFLAFEEPLGMALASIALCLSALTAFVIGIFVKYRDTPIVKANNQALSYILLITLKFCFLCSLNFIGQPNTAACILQQTTFGVAFTVALATVLAKAITVVLAFKVSFPG--RMVRWLMISRGPYYIVPICTLIQLLLCGIWMTMSPPFIDQDPHTEHGHIIILCNKGSSLAFHAVLGYLCLLALGSYTMAFLSRNLPDTFNESKFLSLSMLVFFCVWVTFLPVYYSTKGKVMVAMEVFSILASSTALLAFIFGPKCYIILLRPDKNSFNHVRKKAHFRRKNSPKI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q2J5-1", "uniprot_id": "E9Q2J5_MOUSE", "id": "E9Q2J5-1", "name": "", "aln": "----MFSWIFFAWLLQNHKVSSDTVHVTKNFSACYYLISEEF------HHEEDVMIGAFFPLHTLYTEKKKPHSTKPYVYLDYYIQYNFKNYQYILALLFAIEEINRNPNILPNISLGFDFYNNEYTERNILRFTCRWLTAHVKRAMIPNYTCKRRNVIAALTG-SSWITSAQIGTLLQLFKFPQITFGPYEPTLSDDGQYSSLYQMAPKDTSLSLAIVSFMVHFSWSWIGLIIPDNHKGNKILSEFREEMERNKICIAFLKMIPATWTSYFTRFWENMDETN---VIIIYGDIDSLEILMQIIGQRLLTWNIWIMNNEP--HIIELSDYFMLDSFHGSFIFRHNYRDNIEFTKFIQRVNPYKYPEDIYLPKLWNFFFKCSFSDINCHVLDN----CKTNASLDLLPSFIFDVVMSEESTNIYNGVYALAHSLHQMRLQLLQMQAFENGE-----EMVFFPWQLNTFLKDIEVKDKR---NLDWKQTIDTEYDILNLWNLPKGLGLKVKIGSFSANAPQGQQLSLSEQIIQWPEIFSEVPQSVCSESCRPGFRKVSLDDKAICCYKCTPCADNEISNETDVDQCVKCPESHYANTEKSNCFPKSVSFLAYEDPLGMALASIALCLSALTVFVIGIFVKNRDTPIVKANNRTLSYILLITLTFCFLCSLNFIGQPNTAACILQQTTFAVAFTMALATVLAKAITVVLAFKISFPG--RMLRWLMISRGPRYIIPICTLIQLLLCGIWMATSPPFIDQDVNTEDGYIILLCNKGSAVAFHSVLGYLCFLALGSYTMAFLSRNLPDTFNESKFLSFSMLVFFCVWVTFLPVYHSTKGKVMVAMEVFSILASSTALLAFIFGPKCYIILLRPEKNSFNHIRKKTQSRRKKSPKM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1QSW4-1", "uniprot_id": "F1QSW4_DANRE", "id": "F1QSW4-1", "name": "", "aln": "MSIHVLSWLTLSVPVLLLWPVCGSGTEVTPLETCVYLITPQYSDELGTYQDGDVIIGGLINLHNLAATPDLSFTRKP--GLAQCLEFQERTYRWFQAIVFTVEEINQHPSLLPGVKLGYHIMDSCSRYPHSLTAAMSMISGGNK-------TCGPTKPAKLLIGDSSSTQSILLSTTLVPLKIPMISYLAGCPCLSDRQKYPNFFRTIPSDFYQARTMVQIAKRFGWTWIGAVIADSDNGHGTLQALEEEIKGTGICLAFYHTLYRERLQKDVAFAARTVQASSARVILVLAWYTDVEAFLLELMRRNVTDRLFLASEIWSTSYNIMANPQLYTISKGTLGVALRSAPIPGFSAHLQQLHPSRYPEDKFLRTLWENTFGCSPTISSSKIIQNSLPPCSGRESLEGHIEFIDTSHLT-VSYNIYLAVYAAAHALHSLLECNSQNHTDSKIKPKCSSPDNITPAQLLQHVKDVQYTTQLGEEFYFLEGGIPPVYDLVNWQIAPDGSLQYAFIG-----HVDGNQLSINDSAITWPGDSGKVPISVCTSECPPGTRKAIKKGLPVCCFDCLPCTEGEISNSTGSIKCYRCPKEFWSNSYKNECVARETEFLSVKETMGITLMSVAVSGAVMTTTVAVIFLYHRNTPIVKANNSELSFLLLLSLKLCFLCALVFVGQPSLWSCRIQQAAFGISFVLCISCILVKTFVVLIAFHSTRPESSALIKWFGLGK-QRGIVLVFTCVQVVICAIWLCVSPPLPYQNFGMHRSKVILECTIGSVVGFTCVLGYIGFLATVCFLLAFFARKLPDNFNEAKYITFSMLIFCAVWVAFVPAYVSSPGKYSVVVEVFAILASSFGLLFCIFVPKCYIILLKPENNTKKFLMGKE----------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 250, "similar_positions": 305, "identity": "28.09%" }, { "cls_id": "homologset.agr.MGI:1316678", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZC52-1", "uniprot_id": "D3ZC52_RAT", "id": "D3ZC52-1", "name": "Cell cycle checkpoint protein RAD1", "aln": "MPLLTQYNEDEYEQYCLVASLDNVRNLSTVLKAIHFKEHATCFATKNGIKVTVENAKCVQANAFIQADVFQEFIIQEE---SVTFRINLTILLDCLSIFGSSPTPGTLTALRMCYQGYGHPLMLFLE---EGGVVTVCKITTQEPED-TLDFDFCSTN-VMNKIILQSEGLREAFSELDMT----GDVLQITVSPDKPYFRLSTFGNAGNSH-LDYPKDS---DLVEAFHCNKTQINR-------YKLSLLKPSTKALALSCKVSIRTDNRGFLSLQYMIRNEDGQI-------------------------CFVEYYCCPDEEVPES----------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QWZ1-1", "uniprot_id": "RAD1_MOUSE", "id": "Q9QWZ1-1", "name": "Cell cycle checkpoint protein RAD1", "aln": "MPLLTQYNEEEYEQYCLVASLDNVRNLSTVLKAIHFREHATCFATKNGIKVTVENAKCVQANAFIQADVFQEFVIQEE---SVTFRINLTILLDCLSIFGSSPTPGTLTALRMCYQGYGHPLMLFLE---EGGVVTVCKITTQEPEE-TLDFDFCSTN-VMNKIILQSEGLREAFSELDMT----GDVLQITVSPDKPYFRLSTFGNAGNSH-LDYPKDS---DLVEAFHCDKTQVNR-------YKLSLLKPSTKALALSCKVSIRTDNRGFLSLQYMIRNEDGQI-------------------------CFVEYYCCPDEEVPES----------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60671-1", "uniprot_id": "RAD1_HUMAN", "id": "O60671-1", "name": "Cell cycle checkpoint protein RAD1", "aln": "MPLLTQQIQDEDDQYSLVASLDNVRNLSTILKAIHFREHATCFATKNGIKVTVENAKCVQANAFIQAGIFQEFKVQEE---SVTFRINLTVLLDCLSIFGSSPMPGTLTALRMCYQGYGYPLMLFLE---EGGVVTVCKINTQEPEE-TLDFDFCSTN-VINKIILQSEGLREAFSELDMT----SEVLQITMSPDKPYFRLSTFGNAGSSH-LDYPKDS---DLMEAFHCNQTQVNR-------YKISLLKPSTKALVLSCKVSIRTDNRGFLSLQYMIRNEDGQI-------------------------CFVEYYCCPDEEVPESES--------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VQD4-1", "uniprot_id": "RAD1_DROME", "id": "Q9VQD4-1", "name": "DNA repair protein Rad1", "aln": "---MTDVEPSPYGDCKFVARVEHIKTFIQAIKSICFNDYGMVQVSEDGLRITVEQGKSIQATLFMPPGAFMEFRVQD----FQCFGVKMNVLSECLSLFGSADCS-----LRMMYRDKGDPLKIILYPHDDDDVSTECAIKTMDCDE-PIDYDQNLKDPDLNVIFVRGPNLSKVFNELEKS----AEEFEFVTSPNRPHFKITTVGIMQAVFSVEVAKTS---PMMMMFNCKQTVVAR-------YKSQQIRMTNKAMQSATKVAIKTNSVGLLELHLVMQGDSQEE-------------------------IFIQFFIIPLLNTD------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P48581-1", "uniprot_id": "RAD17_YEAST", "id": "P48581-1", "name": "DNA damage checkpoint control protein RAD17", "aln": "---MRINSELANKFSASTVHLEHITTALSCLTPFGSKDDVLIFIDADGLSFVRENNHVIKIQLLLSRELFMSYSYRNETEDHMKLCVKINHILDSVSVMNRNSDD--IVECTLSYDGHGSPFVLIFEDSFISERVEYSTYLIKDFDTNGLELDRERIS---FEAIIKGEALHSALKDLKEIGCKECYVYAKTEANDENVFALISKSQLGFSK-IKLPSNRSILEKLQVFDGDSTTVIDGFAVIGFFDFTSFDKIRKSTKIASKVLFRMDVHGVLSVNILSQTDDVIITDTTRPSNNRPGSIRQLQLPKDYPGIVIEVCMLEKESIDEAAQTEIELLMETNELGNRNSFKKSTIRKRYGTDKGNETSNDNLLQLNGKKIKLPSEEENNKNRESEDEENHCKYPTKDIPIFF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .. :::: . :..: .: :*: .. *: : :: :: * .: :: : :::. : :.:*::. : * . * *: ::: . . : : :: * . :::. * ..:.:*. . : :. * : : . :. .. : *. ..* : :. : *: : ** :: : *.*.:: : : :. .:: . ", "identical_positions": 18, "similar_positions": 99, "identity": "4.39%" }, { "cls_id": "homologset.agr.MGI:1316687", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A2R8Q4J7-1", "uniprot_id": "A0A2R8Q4J7_DANRE", "id": "A0A2R8Q4J7-1", "name": "", "aln": "---------------------------------------------MDKKNE-KGEARGKGGTKPDKPEAFL-QVERVPN-----FNLLPKNVKRRVYALKRLQLQSGNIEAKFYEEVHELERKYAGLYQPILDKRREIVTGAVEPTDEECEWHSDKE-EDELADDLQKKAALEEKQADSASAVDPKGIPDFWLTIFKHVDMLGEMLQEHDEPILKHLQDVTVKFSEPGQP-MSFTLEFHFEPNSYFSNTVLTKVYKMKSEPDAADPFSFEGPEIVDCEGCKIDWHK-GKDVTVKIVKKKQKHKGRGTIRTVSKEIPQDSFFNFFNPVKASPD--GMDEDLD--FTLATDFEIGHFFRERVIPRAVLYFTGEALEDDESFEEEDLEEGEEEDLDE------EGEEEEEGDFDP-TKDPPPAECKQQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AC58FZ21-1", "uniprot_id": "A0AC58FZ21_DANRE", "id": "A0AC58FZ21-1", "name": "", "aln": "------------------------------MTLSITAEYLSCSIKMEADNEAKGKVSDQAMQNPQALAALQDKLDSVSHS-ASIMDSLPKSVKRRVNALRNLQVNSTHIEAKFYKEVHELERKYSALYQPLFDKRRKVVSGEVEPTDEECEWQSDHEDEAALAEDLKKKAAIEEKTED-ANEEKPKGIPEFWLTIFRSVDMLSDMLQEHDEPILKHLHDIKVIFSGPDQP-MSFTLEFHFEPNEYFTNTVLTKVYKMKSEPDADDPFSFEGPEIIDCEGCEIDWQK-GKDVTVKTIKKKQKHKGRGTARVITKQVPNDSFFNFFNPIKVSPDK-ELDEDSE--YTLATDFEIGHFFRERIVPRAVLYFTGEALEDDESFEEEELDEGEEEDQDD------EEEEEEEEEGDSKTGDPQPAECKQQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q78ZA7-1", "uniprot_id": "NP1L4_MOUSE", "id": "Q78ZA7-1", "name": "Nucleosome assembly protein 1-like 4", "aln": "-----------------------------MAENSLSDGGPADSVEAAKNASNTEKLTDQVMQNPQVLAALQERLDNVSHTPSSYIETLPKAVKRRINALKQLQVRCAHIEAKFYEEVHDLERKYAALYQPLFDKRREFITGDVEPTDAESAWHSENEEEDKLAGDMKNKVVIAEKEAATVEELNPKGIPEFWFTIFRNVDMLSELVQEYDEPILKHLQDIKVKFSDPGQP-MSFVLEFHFEPNDYFTNPVLTKTYKMKSEPDKADPFSFEGPEIVDCDGCTIDWKK-GKNVTVKTIKKKQKHKGRGTVRTITKQVPNESFFNFFSPLKASGDGESLDEDSE--FTLASDFEIGHFFRERIVPRAVLYFTGEAIEDDDNFEEGEEGEEEELEGDE------EGEDEDDADVNPKV-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5U2Z3-1", "uniprot_id": "NP1L4_RAT", "id": "Q5U2Z3-1", "name": "Nucleosome assembly protein 1-like 4", "aln": "-----------------------------MAENSLSDGGPADSVEAAKNASNTEKLTDQVMQNPQVLAALQERLDNVSHTPSSYIETLPKAVKRRINALKQLQVRCAHIEAKFYEEVHDLERKYAALYQPLFDKRREFITGDVEPTDAESAWHSENEEDDKLAGDMKNKVVIAEKEAAAVEELNPKGIPEFWFTIFRNVDMLSELVQEYDEPILKHLQDIKVKFSDPGQP-MSFVLEFHFEPNDYFTNPVLTKTYKMKSEPDKADPFSFEGPEIVDCDGCTIDWKK-GKNVTVKTIKKKQKHKGRGTVRTITKQVPNESFFNFFSPLKASGDGESLDEDSE--FTLASDFEIGHFFRERIVPRAVLYFTGEAIEDDDNFEEGEEGEEEELEGDE------EGEDEDDADVNPKKEPIQPAECKQQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99733-1", "uniprot_id": "NP1L4_HUMAN", "id": "Q99733-1", "name": "Nucleosome assembly protein 1-like 4", "aln": "-----------------------------MADHSFSDGVPSDSVEAAKNASNTEKLTDQVMQNPRVLAALQERLDNVPHTPSSYIETLPKAVKRRINALKQLQVRCAHIEAKFYEEVHDLERKYAALYQPLFDKRREFITGDVEPTDAESEWHSENEEEEKLAGDMKSKVVVTEKAAATAEEPDPKGIPEFWFTIFRNVDMLSELVQEYDEPILKHLQDIKVKFSDPGQP-MSFVLEFHFEPNDYFTNSVLTKTYKMKSEPDKADPFSFEGPEIVDCDGCTIDWKK-GKNVTVKTIKKKQKHKGRGTVRTITKQVPNESFFNFFNPLKASGDGESLDEDSE--FTLASDFEIGHFFRERIVPRAVLYFTGEAIEDDDNFEEGEEGEEEELEGDE------EGEDEDDAEINPKV-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W1G7-1", "uniprot_id": "Q9W1G7_DROME", "id": "Q9W1G7-1", "name": "", "aln": "-----------------------------------MDAPAEGHVDPESCNEIEDEKSGSDCQSMPAYMNSVMRRQYLQQ----MVKMLPAPVQNRIVFLKNLQLQHLNIEAQFFEDVYKLEQKYQVQYQPLFDKRREIIEGKVDPAEEKPQWKEPESSTDNEADAEHFREALS---SLKSIPKDAKGIPGFWLTVFRNTAIMSEMVQPHDEPAIRKLIDISIKYDNG----HSYTLEFHFDKNEYFSNSVLTKQYVLKSTVDPNDPFAFEGPEIYKCTGCTINWEK-KMNLTVKTIRKKQKHKERGAVRTIVKQVPTDSFFNFFSPPEVPSDQEEVDDDSQ--QILATDFEIGHFLRARIIPKAVLYYTGDIVDDEDDEDEEEYDENEEDEYDD------DDAPPPKGPKSAGIKKQSPNDCPNQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VAZ1-1", "uniprot_id": "Q9VAZ1_DROME", "id": "Q9VAZ1-1", "name": "", "aln": "------------------------------------------------------METVRNRNPPRMKYTAPPKMESDLN--------FTEKEKKTLTELKQLYLETINLDVALQRDIYNIEKKYEDKHNIIFDKRKKILDEFRKQNHGDVETN--------------------------------QSVPNFWLRVLK--ASYTEFISKRDEKILECLSDIRSRLYNEP-V-VKFDIEFHFDPNDYFTNTVLTKTYFLNCLPDPDDPLAYDGAEIYKCEGCVIDWKQ-TKDQTKTENQEP-------------------SFFEFFSPPLLPEDTLDPNYCDVN-AMLQNDFEVGFYLKERVIPKAVIFFTGEIADCQSSSGSETESEDTEDESDA------EEEDGVDK-----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P25293-1", "uniprot_id": "NAP1_YEAST", "id": "P25293-1", "name": "Nucleosome assembly protein", "aln": "MSDPIRTKPKSSMQIDNAPTPHNTPASVLNPSYLKNGNPVRAQAQEQDDKIGTINEEDILANQPLLLQSIQDRLGSLVGQDSGYVGGLPKNVKEKLLSLKTLQSELFEVEKEFQVEMFELENKFLQKYKPIWEQRSRIISGQEQPKPEQIAKGQEIVESLNETELLVDEEEKAQ---NDSEEEQVKGIPSFWLTALENLPIVCDTITDRDAEVLEYLQDIGLEYLTDGRPGFKLLFRFDSSANPFFTNDILCKTYFYQKELGYSGDFIYD-----HAEGCEISWKDNAHNVTVDLEMRKQRNKTTKQVRTIEKITPIESFFNFFDPPKIQNEDQDEELEEDLEERLALDYSIGEQLKDKLIPRAVDWFTGAALEFEFEEDEEEADEDEDEEEDDDHGLEDDDGESAEEQDDFAGRPEQAPECKQS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :. :. : *: * . .:: : ::..:*.*: :: : ::* ..: . . :.:* **: :. : : * :. * *: . :.*. . * :*:* :* * * : . . : :: .. ** *.*.. : * . ***:**.* : : * *:.:* :: :::*:** ::** : : . . * : : * : . ", "identical_positions": 39, "similar_positions": 84, "identity": "9.18%" }, { "cls_id": "homologset.agr.MGI:1316696", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0T301-1", "uniprot_id": "A0T301_DANRE", "id": "A0T301-1", "name": "", "aln": "--------------------------------MWVILNISIYLIFNFIMSASILGSNTCQLQGHFRLNEMYHDGDVILGGLFEVDFLTVFPDLDFKTEPEPPYCVQFDMESFQQAQTMAFAIDEINKNPNLLPNITLGYHLFDNCVMLGMAFRAAISMASGTEEFFNNINCTGPPPVIGIVGDSSSTVSIAISSILGLFRVP---IVSHYATCSCLSDRKKYPSFFRTIPSDAFQVRAMVQILKYFRWTWVGLIYSDDDYGVYAAQSFQQEMQLFGGCVAFSEVLPHDNN--LEDIKHITKMIQASTARVIVVFSTPSFLIPLIDELVLQNMTDRQWIASEAWATSFVHHSPRLLPFLKGTLGIAIRRGEIQGLYEFLLRLQPTNDPKNNMIRIFWEIMFGCNFETGGKKNSGDQVINICTGQEDLRTTKTPYTEVSELRASYNVYKAVYALAHALNDLMQCEDGRGPFSVNSCADITNLKPWQLVHYLQNVNFTTDFGDHVSFDKNGDALAIYDVLNWQPSSDGSIRAQTVGVVNEEVATGMVLTLDEDALYWNFESKKPPSSVCSESCAPGTRLATIKGLPVCCFDCLPCGDGEISNITGAVECTMCPDEFWSNLDKDQCIPKEVEFLSYEDPLGISLTTASLLGTCFCVLVMFVFAVHRNTPIVRANNSELSFLLLLSLKMCFLCALLFIGQPQLWTCQLRHVVFGISFVLCISSILVKTMVVIAVFKSSRPESKGAMKWFGAVQQRCTVLVLTAIQVVICAVWLSTASPAPHKNNQYIRSKIVYECAIGSVAGFSMLLAYIGLLAAVSFLLAFLARNLPDNFNEAKFITFSMLIFCAVWIAFVPAYVSSPGKYAVAVEIFAILASSFGLLLAIFAPKCYIILLHPERNTKKAIMGKEAQNT", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1PU52-1", "uniprot_id": "A0A8M1PU52_DANRE", "id": "A0A8M1PU52-1", "name": "", "aln": "--------------------------------MWISLNIFLYLSLNCIFAASVVNPGTCQLQGHFKLNGMYQDGDFILGGLFEVHFFTLFPKLSFKSEPEPPYCEKFDMESFQQAQTMVFAIDEINKNPNLLPNITLGYHLYDNCVMLGMAFRAAISLASGTEEYFSNLNCTGPPPVIGVVGDPGSTPSIAISSVLGLFRVP---IVSHYATCSCLSDRKKYPSFFRTIPSDAFQVRAMVRILSHFGWTWVGLIYSDDDYGIYASVSFQQEMQQFGSCISFSEILPHDNN--PKDIQRIMEVIKASTASVVVVFSTSSYLMPLIDEVVLQNLTGRQWIASEAWATSPVFHTPRYLPFLGGTLGIAIRRGEILGLQEFLLHIHASNNPKDNMLKIFWENMFRCSFETRSKDTIGEQEKSICTGHEDLSTTKTPYTDVSGLRASYNVYKAVYALAHALHDLMECEEGRGPFDGNSCGNITNLKPWQLVHYLQKVNFKTGFGDHVSFDENGDALAIYDVLNWHPSSDGSIRLHTVGVVNEGAGTGKVLSLDESALYWNFQTKNPPRSVCSASCPPGTRQAMRKGLPICCFDCLPCGDGEISNATDSTECVTCPDEFWSNFDKNQCVPKEVEFLSYEDPLGISLTTASLLGTCFCALVMIIFALHLNTPIVRANNSELSFLLLLSLKLCFLCVLLFIGQPQLWTCQLRHVVFGISFVLCISSILVKTMVVIAVFKSSRPEGKGTMKWFGAAQQRCTVLVLTALQVVICAVWLSNASPTPIKNNQYIRSKIVYECAIGSVAGFSLLLGYIGLLAAISFLLAFLARNLPDNFNEAKFITFSMLIFCAVWIAFVPAYVSSPGKYAVAVEIFAILASSFGLLVAIFAPKCYIILLHPERNTKKAIIRRETKKR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8N7T6Z6-1", "uniprot_id": "A0A8N7T6Z6_DANRE", "id": "A0A8N7T6Z6-1", "name": "", "aln": "--------------------------------MCITLYLSLCLCFKHIYADSIHRLRSCQLQGRFKLNGMYQDGDFILGGLFHVHFFTVFPELSFRMEPQQPYCEKFNMEGLQHAQTMAFAINEINKNPTLLPNITLGYHLYDNCVMLRMAFRAAMSLASGTEDSYSNLNCTGPPPVIGIVGDASSTPSIAISSVLGLFRVP---IVSHYATCSCLSDRKKYPSFFRTIPSDAFQVRAMVQILKHFKWTWVGLLYSGDDYGVYAAQMFHKEMQLSGHCVAFSEILPNDHN--PKDIQRIIRVIQGSTARVVVVFALSSFLIPLMDEVVLQNMTGCQWIASEAWATSLEYHTPRFLPFLGGTLGIAIRRGEIEGLHEFLLRIRPSNDTSQNIVRIFWENLFGCRFETGGLKTGREQEKMECTGQEDLSTTNTPYTDVSGLRASYNVYKAVYALAHGLHDLMQCEEGRGPFIGNSCADITSLKPWQLVHYLQNVNFTTGFGDHVTFDKNGDALAIYDVLNWQPSSDGSITVHKIGVVYEGATTGMMLTLDADAIYWNFETKKPPLSVCSESCPPGTRQATRKGLPLCCFDCLPCGDGEFSNTRDAVECMMCPDEFWSSPDKDQCVPKEVEFLSYEDPLGISLTTASLLGTCFCALVMIIFALHHNTPIVRANNSELSFLLLLSLKLCFLCVLLFIGRPQLWTCQLRHAVFGISFVLCVSSILVKTMVVIAVFKSSRPEGKGAMKWFGASQQRCTVLVLTALQVVICAVWLSTASPTPHKNNHYFRSIIVYECAIGSVAGFSLLLGYIGLLAAISFLLAFLARNLPDNFNEAKFITFSMLIFCAVWIAFVPAYVSSPGKYAVAVEIFAILASSFALLLAIFAPKCYIILLHPERNTKNAIMGRETQNK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1Q146-1", "uniprot_id": "A0A8M1Q146_DANRE", "id": "A0A8M1Q146-1", "name": "", "aln": "---------------------------------------------------------------------MYQDGDFILGGLFEVHFFTVFPDLTFTTNPKSPYCEIFNMEGFQHAQTMAFAIEEINKNPKLLPNITLGYHLYDNCVMLGMAFRAAISLTSGTEESFLNLNCSGPSPVIGIVGDPSSTPSIAISSVLGLFRVP---IVSHYATCSCLSNRKKYPSFFRTIPSDAFQVRAIVQVLKHFKWTWVGLLYSDDDYGVYAAQSFQQEMRQFGLCAAFSEFLPHDNN--PRTIQHIMGVIQGSTAKAVVVFAPSSFLIPLMNEVVLQNMTGRQWIASEAWATSLESHIPSFQPFLRGTIGIAIRRGEIQRLHDFLLRIRPSNDPKNYMLRIFWENMFGCSFGKG--DTEGEQVIKVCTGQEDLSTTNTPYTDVSGLRAAYNVYKAVYALAHALHDLMECEEGKGPFSKNSCADKTNLKPWQVVHYLQNVNFTTGFGDYVSFDKNGDALAIYDVLNWQPSSDESIRIYTVGVVKEGTETGMVLTLDEDAIFWNFETRKPPRSVCSESCPPGTRRATRKGLPVCCFDCLPCGDGEISNTTNAVECFLCPDEFWSNQYNNHCVPKEVEFLSYEDPLGISLTTASLLGTCFCALVIFVFALHRNTPIVRANNSELSFLLLLSLKLCFLCVLLFIGRPQLWTCQLRHVVFGISFVLCMSSILVKTMVVIAVFKSSRPEGKGAIKWFGAVQQRSTVVVLTVLQVLICAVWLSTASPTPYKNNQYIRSKIVYECAIGSVVGFSMLLSYIGFLAAASFLLAFLARNLPDNFNEAKFITFSMLIFSAVWIAFVPAYVSSPGKYTVAVEIFAILASTFGLLIAIFAPKCYIILLHPERNTKNVIMGRETQNK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32TCB3-1", "uniprot_id": "A0AB32TCB3_DANRE", "id": "A0AB32TCB3-1", "name": "", "aln": "----MNFGAGLRTGSRNGNEKWKRMTFCRSSAFCHMFSSTLYLISSMARHAVVLRAGACQLQGRFRLNGMYQDGDVILGGLFEAHFFTLFPELTFRTEPAPPYCEIFNMESFQYAQTMAFAINEINRNPSLLPNISLGYHLYDNCVMLGMALRAAMSLVSGIEESFLNLNCTGPPPIIGVVGDPSSTPSIAISSVLGLFRVP---IVSHYATCSCLSDRKKYPSFFRTIPSDAFQVRAMIQLISHFGWTWIGLLYSDDDYGTYAAQSFHQEMQLFGFCIAFSEPLRYDSN--PRDIQRLMEVIQASTSTVVVVFSPSTLVIPLMNEVVLQNMTGRQWIASESWATSPVFYTPRFLPFLGGTLGIAIRRGEIEGLREFLLQLRPKNDPRNNMLKIFWENMFGCSFETG------PHVKNVCTGQEDLSTTNTPYTDVSELRAANNVYKAVYALAHALHDLMKCEEGKGPFSKNSCAEISNLKPWQLVHYLQKVNFSTRFGDHVSFNKNGDALAIYDVMNWQPGSDRSIRIHTVGVVSEELEKGLMLTLDEDAIYWNFETKKPPQSVCSESCPRGSRRATRKGHPVCCFDCLPCRDGEISNTTDATKCTVCPDDFWSNLYKDQCIPKEVEFLSYNDPLGISLTTASLLGTCFCAFVMVIFVHHHNTPIVRANNSELSFLLLFSLKLCFLCVLLFIGRPQLWTCQLRHAVFGISFVLCISSILVKTMVVIAVFKSSRPEGKMAMKWFGAAQQRCTILALTAIQVVICVVWLSTASPTPHKNNLYIRSIIVYECTIGSVTGFSMLLGYIGLLAAVSFLIAFLARNLPDNFNEAKFITFSMLIFCAVWITFVPAYVSSPGKYSVAVEIFAILASSFGLLVSIFAPKCYIILLHPERNNKKAIMGRETH--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8N7UVL1-1", "uniprot_id": "A0A8N7UVL1_DANRE", "id": "A0A8N7UVL1-1", "name": "", "aln": "MLTWHRLFIKATPSKVFIINNIHRGELKRNVEMWIIAKICLYLSFSCISVASIFRSGPCQLQGQFRLNGMFQEGDLILGGLFEVHFLTVFPEQSFRTEPEPPYCEQFDMASFQQAQTMVFAIDEINRNPNLLPNITLGYYLYDNCVKLSVAFRAAMALVSGTEESFSSLNCTGPPPVIAIVGDPGSTHSIAISSILGLFRVP---MVSYFATCSCLSDRKTYPSFFRTIPSDAFQVRAMVQILKRFGWTWVGLLYSDDDYGIYAAQSFQKEMQLFGACVGFSEMLPRDNN--HEDIQSIVEVIQTSTARVVVVFSTEAYLLPLMDEVALKNVTGRQWIASEAWATSPVFHTQHLLPFLGGTLGIAIRRGEIQGLKEFLYYLHPDSNTRNNIVRIFWENIFGCSFEIG------GRERKVCTGQEDLKSTNTAYTDVSGLRASYNAYKAVYALAHALHDLMQCEDGRGPFSGNKCADQINLQPWQVVHYLQKVNFTTGFGDHVSFDENGDALAIYDVMNWQPSSDGAISVSTVGVVNEGASMKMVLTLKENSIFWNFKNRKPPQSVCSESCPPGTRQVRRKGLPVCCFDCLPCADGEISNTTDAIECKICPDELWPNPNKDQCVPKEEDFLSFEDPLGISLTTASLLGTCFCALVMVIFSHHRNTPVVRANNSELSFLLLLSLKLCFLCVLLFIGRPKLWTCQLRHAAFGISFVLCVSSILVKTMVVIAVFKSSRPESKSAMKWFGVAQQRGTVMALTTLQIVICTVWLSMASPKPYKNSLYISSKVVYECDIGSVVGFSLLLGYIGLLAAVSFLFAFLARNLPDNFNEAKFITFSMLIFCAVWITFVPAYVSSPGKYAVAVEIFAILASSFGLLVAIFAPKCYMILFHPERNTKKSIMGRATQIK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F7F1X2-1", "uniprot_id": "F7F1X2_RAT", "id": "F7F1X2-1", "name": "", "aln": "--------------------------------MFILMVVFFLLHHPLLMANFIDPWCFWRTN-----LNEVKEKNLDINCAFILGAVQLPMEKDYFNETLN---VLKTTKNNKYALALAFSMEEINRNPDLLPNMSLVIKHTLSYCDGN---TADHIFKEKFYKPLPNYVCNEETMCSFMLIGLNWVLSLTLFKDLDIFSFPRFLQISYGPFHSIFSDNEQFPYLYQMTPKDTSLALAIVSFLLYFNWNWVGLVISDNDEGNQFLSELKKETQNKEICFAFVNMMSIHEHSSYQKTEMYYNQIVMSSTNIIIIYGKTNSIIELSFRMWVSPVIQRIWVTNSELDFPTSMRDFTHGTFYG-TLTFLHHHGEISGFTNFFETWDHLRSRDLNLLIPEWKYFSYDASGSN------CKILRNYSSNASLEWITEQKFHMAFNDYSHSIYNAVYAMAHALHETNLQEVDNKEIRNGKGASTHCLK---VNSFLRKTHFTNSHGERVIMKQRVRVQEDYDIVHIQNFSQHLRIKMKIGKFSPYFTHGGPFHLYEDMIQLATGSRKMPSSVCSADCSPGFRKSWKEGMAPCCFICSLCPENEISNETNMDQCVNCPEYQYANTEKNKCIQKDVIFLSYEDPLGMALALIAFCLSAFTAVVLWVFVKHHDTPIVKANNRILSYILIMSLMFCFLCSFFFIGHPNRGTCILQQITFGIVFTVAVSTVLAKTITVILAFKLRDP-GRSLRNFLVSGAPNYIIPICSLLQCILCAIWLAVSPPFVDIDEHSEHGHIMIVCNKGSIMAFYCVLGYLACLALGSFTTAFLAKNLPDTFNEAKFLTFSMLVFCSVWVTFLPVYHSTRGRVMVAVEIFSILASSAGMFGCIFAPKIYIILMKPERNSIQKFREKSYF--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3ZE87-1", "uniprot_id": "D3ZE87_RAT", "id": "D3ZE87-1", "name": "G-protein coupled receptors family 3 profile domain-containing protein", "aln": "--------------------------------MFILMVVFFLLNLPLLMANFIDSWCFWRIN-----LNESKKKDLEISCAFILGAVQLPMEKDYYNETLN---VLKTTKTNKYALALAFTMEEINRNPDILPNMSLIIKHTLSYCDGK---TALHIAKEKFFRPLPNYVCSEESMCSFLLIGLNWMSSIILFRDLDTFFFPRFLQISYGPFHSIFSDNEQFPYLYQMTPKDTSLALAMVSFILYFNWNWIGLIISDNDEGNQFLSELKKEAQNKEICFAFVNMMAIDDISFYDKTEMYYNQIVMSSTNVIIIYGETDSIIELSFRMWESPVIQRIWVTKSELDFPTSKRDLNHGTFYG-TLTFLHHHGEISEFKNFVEMWDHLRSRNLNLLISEWKYFSYETSGSN------CKILRNFTSNSSLEWLTEQKFQMAFNDESNSVYNAVYAMAHALHENNLQEIDKQEIRNGKGAGTHCLK---LNSFLRKTHFTNPLGDRVIMKHRERVQEDYDIVHIHNFSQHLWIKVKIGKFSPYFPNGRLFHLYGDMIELATGSKKMPSSVCSADCSPGFRKTWKEGMAACCFVCSLCPENEISNETNMDQCVNCPEYQYANKEKSKCIQKGVIFLSYDDHLGMLLAIIAFCLSAFTAAILWVFVMHHNTPIVKANNRILSYILIMSLMFCFLCSFFFIGHPNRATCILQQITFGIVFTVSVSTVLAKTITVVLAFKITDP-GRRLRNFLVLGLPNYIIPICSLLQCILCTIWLAVSPPFVDIDQHSEHGNIIIVCNKGSVMAFYCVLGYLACLAFGSFTMAFLAKNLPDTFNEAKFLTFSMLVFCSVWVTFLPVYHSTKGRVMVAVEVFSILASSAGMLGCIFAPKLYIILMRPDRNYIQKIREKSF---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "G3V911-1", "uniprot_id": "G3V911_RAT", "id": "G3V911-1", "name": "", "aln": "--------------------------------MLILMVIFFLLNIPFLLANFMDPRCFWKIN-----LNEIKDEVLGMTCSFILETVQKTMDKDYFNQTLN---VLNTTTNHKYALALAFTVDEINRNPDLLPNMSLIIKYNLGHCDGKTVTTLSDLFNPNNHLHFPNYLCNEGIMCLVLLTGPHWRASLYLWISVYVYLSPHFLQLSYGPFYSIFSDNEQYPYLYQMGPKDSSLALAMVSFIIYFKWNWVGLFISDDDQGNQFLSELKKESQTKDICFAFVNMVSVSDVSYYHKTEMYYNQIVMSSTKVIIIYGETNSIIELSFRMWSSPVKQRIWVTTKQFDCPTSKRDLTHGTFYG-TLTFLHHYGEISGFKNFVQTRYNLRSTDLYLVTPEWKYFNYEASASN------CKILRNYLSNISLEWLMEQKFDMSFSDYSHNIYNAVYAIAHALHEKNLQEVENQAINNAKGENTHCLK---LNSFLRKTHFTNSLGNRVIMKQREVVHGDYNIVHMWNFSQRLGIKVKIGQFSPHFPQGQQLHLYVDMTELATGSRKMPSSVCSADCHPGFRRIWKEEMAVCCFVCNPCPENEISNETNMDQCANCPEYQYANTEKNKCIQKGVIVLSYEDPLGMALALIAFCFSAFTVVVFWVFVKHHDTPIVKANNRILSYLLIVSLMFCFLCSFFFIGYPNRATCILQQITFGIFFTVAISTVLAKTITVVLAFKVTDP-GRQLRIFLVSGTPNYIIPICSLLQCILCAIWLAVSPPFVDIDEHSEHGHIIIVCNKGSITAFYCVLGYLACLAFGSFTIAFLAKNLPDTFNEAKFLTFSMLVFCAVWVTFLPVYHSTKGKVMVAVEIFSILASSAGMLGCIFAPKVYIILMRPDRNSIHKIREKSYF--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3ZB66-1", "uniprot_id": "D3ZB66_RAT", "id": "D3ZB66-1", "name": "", "aln": "--------------------------------MFIFMVVFFLINIPLLMANVIDPRCFLRIN-----LDEVKDGDLQSTCSFILEAVQIPMEKDYFNQTLN---VLKTAKNHKYALTLAFSIDEINRNPDLLPNMSLIIKYSFGYCDGKTVTPTPYLFHEEFEKPIPNYFCKEETKCTFLLTGPHWGTSLLFLTKLDIFSSPRFLQLTYGPFHSTLNDNEQFPYLYQMAPKDTSLALAIVSFILYFNWNWVGLFISDEDQGNRFLSELKKVSESKKICFAFVSMISFSELLFHHKVEMYYDQIVMSSTSVIIIYGEGNSITELNFRIWESPVKHRIWVTTKQWNFPTSNRDLTHDTFYG-TFTFQHHHGEISGFNNLVQTWYQLRSTDLCQVMPDWKYLNYEGSASN------CEILENYTSGASLEWLLEQKFDMAFSDDSYNIYNAVYAMAHAFHELNLQQVDNQAIDNEKGASSHCLK---LNSFLRKTHFTNPLGDKVIMKQREILQEDYDIFHTQYFSEHLGIKVKIGKVSQYFKRDQHFHLYVDMIELATGSKKMPSSVCTEDCGPGFRRIWKEGMAACCFVCKPCPENEISNDTNMDQCMNCPEYQFANTKHNKCIQKGVLFLSYEDPLGMALALIAFCFSAFTAVVLWVFVKHHDTPIVKANNRNLSYLLIISLMFCFLCTFFFIGHPNRATCILQQITFGIVFTVAVSTVLAKTATVVLAFKVTDP-GRRLRNVLVSGTPNYIIPICSLFQCILCAIWLAVSPPFVDIDDYSEHGHIIIVCNKGSVTAFYCVLGYLACLALGSFTVAFLAKNLPDTFNEAKFLTFSMLVFCSVWVTFLPVYHSTKGKVMVAVEIFSILASSAGMLGCIFAPKIYIILMRPDRN-ILKFREKSYF--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "K7N686-1", "uniprot_id": "K7N686_MOUSE", "id": "K7N686-1", "name": "", "aln": "--------------------------------MFIFMGVFFLLNITLLMANFIDPRCFWRIN-----LDEITDEYLGLSCAFILAAVQTPTEKDYFNKTLN---FLKTTKNHKYALALVFAMDEINRYPDLLPNMSLIIRYSLGHCDGKTVTPTPYLFHRKKQSPIPNYICNEESMCSFLLSGPNWDESLSFWKYLDSFLSPHILQLSYGSFSSIFSDDEQYPYLYQMAPKDTSLALAMVSFILYLKWNWIGLVIPDDDQGNQFLLELKKQSENKEICFAFVKMISVDEVSFPQKTEIYYKQIVKSLTNVIIIYGETYNFIDLIFRMWEPPILQRIWITTKQLNFPTSKTDISHDTFYG-SLTFLPHHGEISGFKNFVQTWFHLRNTDLYLVMPEWKYINSEDSASN------CKILKNSSSDASFDWLMEQKLDMAFSDNSHNIYNVVHAIAHALHEMNLQQADNQAIDNGKGASSHCLK---VNSFLRRTYFTNPLGDKVFMKQRVIMQDEYDIVHFANLSQHLGIKMKLGKFSPYLPHGRHSHLYVDMIELATGRRKMPSSVCSADCSPGFRRLWKEGMAACCFVCSPCPENEISNETNMDQCVNCPEYQYANTEQNKCIQKGVTFLSYEDPLGMALALMAFCFSAFTAVVLCVFVKHHDTPIVKANNRSLSYLLLMSLMFCFLCSFFFIGLPNKVICVLQQITFGIVFTVAVSTVLAKTVTVVLAFKVTDP-GRRLRYFLVSGTLNYIIPICSLLQCVLCAIWLAVSPPFVDIDEHSQHGHIIIVCNKGSVTAFYCVLGYLACLALGSFTLAFLAKNLPDAFNEAKFLTFSMLVFCSVWVTFLPVYHSTKGKHMVAVEIFSILASSAGMLECIFVPKIYIILMRPERNSTQKIREKSYF--", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . * . . : :. : * ::.*:::***: * :***::* . . *. :: . *: : : : * ::: . * :.: : :* ::: *.*: . *:: .: : *.*:**. ..:* * ::: . * .* . : : * * : ::::. . * .: : *::.. . .* :: : : *** : ::. . : *: : . . .: .:: : . *:.*:*:**.::: : . : . *: : :*:.. *.. *: * :... *::.: *: .:* . * . :: * ***: .* * * : . *** * * :.*:** . :* **: :.. :.:*: * .**::* **: *: :: :.* . :: :* * :**:*:*** **::*:.** :**** ::*** *: * *:: .*** *.:.:*::*.** .*: .** * .: : . : : :* ::*.:**: :.* :. . :: * **: .* :*.*:. ** ** ****:**** ******:*****:*.:**::*:*.* *: *: ****:*:****: .:: .**.** *:**::*:** : : ", "identical_positions": 173, "similar_positions": 239, "identity": "19.12%" }, { "cls_id": "homologset.agr.MGI:1316706", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99P39-1", "uniprot_id": "NFS1_RAT", "id": "Q99P39-1", "name": "Cysteine desulfurase", "aln": "--------MLLRVAWRR----ASLAATSVALRRSSVPTRGLRLR------------VVDHAPHSAVPS------EAEAVL-----------------RPLYMDVRATTPLDPRVLDAMLPYLVNYYGNPHSRTHAYGWESEAAMERARQQVASLIGADPREIIFTSGATESNNIAIKGVARFYRSRKKHLVTTQTEHKCVLDSCRSLEAEGFRVTYLPVQKSGIIDLKELEAAIQPDTSLVSVMTVNNEIGVKQPIAEIGQICSSRKLYFHTDAAQAVGKIPLDVNDMKIDLMSISGHKLYGPKGVGAIYIRRRPRVRVEALQSGGGQERGMRSGTVPTPLVVGLGAACELAQQEMEYDHKRISKLAERLIQKIMKNLPDVVMNGDPKQHYPGCINLSFAYVEGESLLMALKDVALSSGSACTSASLEPSYVLRAIGTDEDLAHSSIRFGIGRFTTEEEVDYTVQKCIHHVKRLREMSPLWEMVQDGIDLKSIKWTQH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z1J3-1", "uniprot_id": "NFS1_MOUSE", "id": "Q9Z1J3-1", "name": "Cysteine desulfurase", "aln": "MVGSVAGNMLLRAAWRR----ASLAATSLALGRSSVPTRGLRLR------------VVDHGPHSPVHS------EAEAVL-----------------RPLYMDVQATTPLDPRVLDAMLPYLVNYYGNPHSRTHAYGWESEAAMERARQQVASLIGADPREIIFTSGATESNNIAIKGVARFYRSRKKHLVTTQTEHKCVLDSCRSLEAEGFRVTYLPVQKSGIIDLKELEAAIQPDTSLVSVMTVNNEIGVKQPIAEIGQICSSRKVYFHTDAAQAVGKIPLDVNDMKIDLMSISGHKLYGPKGVGAIYIRRRPRVRVEALQSGGGQERGMRSGTVPTPLVVGLGAACELAQQEMEYDHKRISKLAERLVQNIMKNLPDVVMNGDPKQHYPGCINLSFAYVEGESLLMALKDVALSSGSACTSASLEPSYVLRAIGTDEDLAHSSIRFGIGRFTTEEEVDYTAEKCIHHVKRLREMSPLWEMVQDGIDLKSIKWTQH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y697-1", "uniprot_id": "NFS1_HUMAN", "id": "Q9Y697-1", "name": "Cysteine desulfurase", "aln": "--------MLLRAAWRR----AAVAVTAAPGPKPAAPTRGLRLR------------VGDRAPQSAVPADTAAAPEVGPVL-----------------RPLYMDVQATTPLDPRVLDAMLPYLINYYGNPHSRTHAYGWESEAAMERARQQVASLIGADPREIIFTSGATESNNIAIKGVARFYRSRKKHLITTQTEHKCVLDSCRSLEAEGFQVTYLPVQKSGIIDLKELEAAIQPDTSLVSVMTVNNEIGVKQPIAEIGRICSSRKVYFHTDAAQAVGKIPLDVNDMKIDLMSISGHKIYGPKGVGAIYIRRRPRVRVEALQSGGGQERGMRSGTVPTPLVVGLGAACEVAQQEMEYDHKRISKLSERLIQNIMKSLPDVVMNGDPKHHYPGCINLSFAYVEGESLLMALKDVALSSGSACTSASLEPSYVLRAIGTDEDLAHSSIRFGIGRFTTEEEVDYTVEKCIQHVKRLREMSPLWEMVQDGIDLKSIKWTQH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VKD3-1", "uniprot_id": "NFS1_DROME", "id": "Q9VKD3-1", "name": "Cysteine desulfurase, mitochondrial", "aln": "-MQKVLGRIQAQVLRSR----ATNALANVVRHEATSSRTAAKPA------------ATSKEFRERQVRFN--IKNEQTEG-----------------RPLYLDAQATTPMDPRVLDAMLPYLTNFYGNPHSRTHAYGWETESAVEKAREQVATLIGADPKEIIFTSGATESNNIAVKGVARFYGTKKRHVITTQTEHKCVLDSCRALENEGFKVTYLPVLANGLIDLQQLEETITSETSLVSIMTVNNEIGVRQPVDEIGKLCRSRRVFFHTDAAQAVGKVPLDVNAMNIDLMSISGHKIYGPKGVGALYVRRRPRVRLEPIQSGGGQERGLRSGTVPAPLAVGLGAAAELSLREMDYDKKWVDFLSNRLLDRISSALPHVIRNGDAKATYNGCLNLSFAYVEGESLLMALKDVALSSGSACTSASLEPSYVLRAIGTDEDLAHSSIRFGIGRFTTVEEVDYTADKCIKHVERLREMSPLWEMVQEGIDLKTIQWSQH", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P25374-1", "uniprot_id": "NFS1_YEAST", "id": "P25374-1", "name": "Cysteine desulfurase", "aln": "MLKSTATRSITRLSQVYNVPAATYRACLVSRRFYSPPAAGVKLDDNFSLETHTDIQAAAKAQASARASASGTTPDAVVASGSTAMSHAYQENTGFGTRPIYLDMQATTPTDPRVLDTMLKFYTGLYGNPHSNTHSYGWETNTAVENARAHVAKMINADPKEIIFTSGATESNNMVLKGVPRFYKKTKKHIITTRTEHKCVLEAARAMMKEGFEVTFLNVDDQGLIDLKELEDAIRPDTCLVSVMAVNNEIGVIQPIKEIGAICRKNKIYFHTDAAQAYGKIHIDVNEMNIDLLSISSHKIYGPKGIGAIYVRRRPRVRLEPLLSGGGQERGLRSGTLAPPLVAGFGEAARLMKKEFDNDQAHIKRLSDKLVKGLLS-AEHTTLNGSPDHRYPGCVNVSFAYVEGESLLMALRDIALSSGSACTSASLEPSYVLHALGKDDALAHSSIRFGIGRFSTEEEVDYVVKAVSDRVKFLRELSPLWEMVQEGIDLNSIKWSGH", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *: : . . : . : . : **:*:* :**** ******:** : . ******.**:****:::*:*.** :**.:*.***:*************:.:***.*** . *:*::**:*******::.*:: ***.**:* * .*:***::** :* .:*.***:*:******* **: *** :* ..:::******** **: :*** *:***:***.**:*****:**:*:*******:*.: ********:****:..**..*:* *..: :*:: *: :. *:::*:. : . .. **... * **:*:**************:*:*******************:*:*.*: *************:* *****... .:*: ***:********:****::*:*: *", "identical_positions": 242, "similar_positions": 122, "identity": "48.59%" }, { "cls_id": "homologset.agr.MGI:1316708", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q12894-1", "uniprot_id": "IFRD2_HUMAN", "id": "Q12894-1", "name": "Interferon-related developmental regulator 2", "aln": "MPRARKGNTLRKGGQRRGGGARSSAQADSGSSDDEAASEARSTASECPSLLSTTAEDSLGGDVVDEQGQQEDLEEKLKEYVDCLTDKSAKTRQGALESLRLALASRLLPDFLLERRLTLADALEKCLKKGKGEEQALAAAVLGLLCVQLGPGPKGEELFHSLQPLLVSVLSDSTASPAARLHCASALGLGCYVAAADIQDLVSCLACLESVFSRFYGLGGSSTSPVVPASLHGLLSAALQAWALLLTICPSTQISHILDR------QLPRLPQLLSSESVNLRIAAGETIALLFELARDLEEEFVYEDMEALCSVLRTLATDSNKYRAKADRRRQRSTFRAVLHSVEGGECEEEIVRFGFEVLYMDSWARHRIYAAFKEVLGSGMHHHLQNNELLRDIFGLGP-VLLLDATALKACKVPRFEKHLYNAAAFKARTKARSRVRDKRADIL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9D8U0-1", "uniprot_id": "IFRD2_MOUSE", "id": "Q9D8U0-1", "name": "Interferon-related developmental regulator 2", "aln": "MPRARKGNALRKGGQRRGGGARSSTQADSGSSEDEAASEARSTTSDCPSLLSATTEDCLGGEAVDEQSQQENLEEKLKGYVDCLTDKSAKTRQGALESLRLALASRLLPDFLLERSLTLADALEKCLKKGKGEEQALAAAVLGILCVQLGPGPKGEELFRSLQPLLISVLSDSTASPTARLHCASALGLGCYVAATDVQDLVSCLACLEGVFSWSCGTSGSAAS-LVPASLHGLLCAALQAWALLLTICPGTHISHILDR------QLPRLPQLLSSESVNLRIAAGEAIALLFELARDLEEDFVYEDMEALCGSLRTLATDSNKYRAKVDRRRQRSIFRAVLHFVEGGECEEETVRFGLEVLYIDSWARHRIYTAFKDVLGSGIHYHLQNNELLRDIFGLGP-VLVLDAAALKACKISRFEKHLYNAAAFKARTKARSRARDKRADIL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9VQI5-1", "uniprot_id": "Q9VQI5_DROME", "id": "Q9VQI5-1", "name": "", "aln": "MPRRNKKSAAGRG------------RTNDSNSEDESFDNVS---------VYSHMSEVASSEATDELAN-ERFEEKFEKALEQATEKSAQTRVQALQAICELLMHRYMPDFVEDRKMTLMDFVEKSIRRGKGQEQVWGARLAPLLVLQMG-GDEG--ISKAMNQFLLNTVQDKSVGFDARAKCCTAVGLLSFLGCEDVGELVHLMQSFEAIFAGSYLRGDDKTPVSVTAEAGTFHAEALNAWGLLLTLIPSGDFVSLMTTGQNMFPSIKKFLGLLQSTHLDVRMAAGETIALILESGRAHEEDFLEDDIAELSEAVKQLATDSHKYRAKRDRKAQRATFRDVLRYLEEDISPEISIRFGTESLTLDSWSIHHQYSAMCTVMGPGMTSQLQENEFIRDIFQLGPRPTNTGINGNAKVKPTKLERHLVNAAAFKARSITRGKNRDKRSAVVT", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** .* .: :* :::...*:**: .:. : : .: ..:..** .: * :***:: :: *:***:** **::: * * :***: :* :** * :**.:::***:**. .* : :* :*:* * :* : :::: :*:..:.*.:.. ** :*.:*:** .::.. *: :** : .:*.:*: ... :. *.*. : . **:**.****: *. .: :: .: :: **.* :::*:****:***::* .* **:*: :*: *. :: *****:***** **: **: ** **: :* . . * :*** * * :***: *: *:*: *:*.*: :**:**::**** *** . . * .::*:** ********: :*.: ****: :: ", "identical_positions": 148, "similar_positions": 155, "identity": "32.89%" }, { "cls_id": "homologset.agr.MGI:1316711", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZB66-1", "uniprot_id": "D3ZB66_RAT", "id": "D3ZB66-1", "name": "", "aln": "MFIFMVVFFLINIPLLMANVIDPR---------CFLRIN------LDEVKDGDLQSTCSFILEAVQIPMEKDYFNQT---LNVLKTAKNHKYALTLAFSIDEINRNPDLLPNMSLIIKYSFGYCDGKTVTPTPYLFHEEFEKPIPNYFCKEETKCTFLLTGPHWGTSLLFLTKLDIFSSPRFLQLTYGPFHSTLNDNEQFPYLYQMAPKDTSLALAIVSFILYFNWNWVGLFISDEDQGNRFLSELKKVSESKKICFAFVSMISFSELLFHHKVEMYYDQIVMSSTSVIIIYGEGNSITELNFRIWESPVKHRIWVTTKQWN--FPTSNRDLTHDTFYGTFTFQHHHGEISGFNNLVQTWYQLRSTDLCQVMPDWK-YLNYEGSASNCEILENYTSGASLEWLLEQKFDMAFS---DDSYNIYNAVYAMAHAFHELNLQQVDNQAIDNEKGASSHCLKLN-----SFLRKTHFTNPLGDKVIMKQREILQEDYDIFHTQYFSEHLGIKVKIGKVSQYFKRDQHFHLYVDMIELATGSKKMPSSVCTEDCGPGFRRIWKEGMAACCFVCKPCPENEISNDTNMDQCMNCPEYQFANTKHNKCIQKGVLFLSYEDPLGMALALIAFCFSAFTAVVLWVFVKHHDTPIVKANNRNLSYLLIISLMFCFLCTFFFIGHPNRATCILQQITFGIVFTVAVSTVLAKTATVVLAFKVTDP-GRRLRNVLVSGTPNYIIPICSLFQCILCAIWLAVSPPFVDIDDYSEHGHIIIVCNKGSVTAFYCVLGYLACLALGSFTVAFLAKNLPDTFNEAKFLTFSMLVFCSVWVTFLPVYHSTKGKVMVAVEIFSILASSAGMLGCIFAPKIYIILMRPDRN-ILKFREKSYF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F8VQD3-1", "uniprot_id": "F8VQD3_MOUSE", "id": "F8VQD3-1", "name": "", "aln": "MFIFMEVFFLLNITLLMANFIDPR---------CFWRIN------LDEIMDEYLGLSCAFILAAVQTPIENDYFNKT---LNVLKTTKNHKYALALVFAMDEINRNPDLLPNMSLIIRYTLGRCDGKTVIPTPYLFRKKKESPIPNYFCNEETMCSYLLTGPHWEVSLGFWKHMNSFLSPRILQLTYGPFHSIFSDDEQYPYLYQMAPKDTSLALAMVSFILYFSWNWIGLVIPDDDQGNQFLLELKKQSENKEICFAFVKMISVDDVSFPQNTEMYYNQIVMSSTNVIIIYGETYNFIDLIFRMWEPPILQRIWITTKQLN--FPTRKKDISHGTFYGSLTFLPHHGVISGFKNFVQTWFHLRNTDLYLVMQEWK-YFNYEDSASTCKILKNNSSNASFDWLMEQKFDMTFS---ENSHNIYNAVHAIAHALHEMNLQQADNQAIDNGKGASSHCLKVN-----SFLRRIYFTNPPGDKVFMKQRVIMHDEYDIVHFVNLSQHLGIKMKLGKFSPYLPHGRHSHLYVDRIELATGRRKMPSSVCSADCSPGFRRLWKEGMAACCFVCSPCPENEISNET--------------------------------------------------TVVLCVFVKHHDTPIVKANNRSLSYLLLMSLMSCFLCSFFFIGLPNRAICVLQQITFGIVFTMAVSTVLAKTVTVVLAFKVTDP-GRRLRNFLVSGTPNYIIPICSLLQCVLCAIWLAVSPPFVDIDEHTLHGHIIIVCNKGSVTAFYCILGYLACLALGNFSVAFLAKNLPDTFNEAKFLTFSMLVFCSVWVTFLPVYHSTKGKHMVAVEIFSILASSAGILGCIFVPKIYIILMRPERNSTQKIREKSYF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1QSW4-1", "uniprot_id": "F1QSW4_DANRE", "id": "F1QSW4-1", "name": "", "aln": "MSIHVLSWLTLSVPVLLLWPVCGSGTEVTPLETCVYLITPQYSDELGTYQDGDVIIGGLINLHNLAATPDLSFTRKPGLAQCLEFQERTYRWFQAIVFTVEEINQHPSLLP------GVKLGYHIMDSCSRYPHSLTAAMSMISGGNKTCGPTKPAKLLIGDSSSTQSILLS--TTLVPLKIPMISYLAGCPCLSDRQKYPNFFRTIPSDFYQARTMVQIAKRFGWTWIGAVIADSDNGHGTLQALEEEIKGTGICLAFYHTLYR--ERLQKDVAFAARTVQASSARVILVLAWYTDVEAFLLELMRRNVTDRLFLASEIWSTSYNIMANPQLYTISKGTLGVALRSAPIPGFSAHLQQLHPSRYPEDKFLRTLWENTFGCSPTISSSKIIQNSLPPCSGRESLEGHIEFIDTSHLTVSYNIYLAVYAAAHALHSLLECNSQNHTDSKIKPKCSSPDNITPAQLLQHVKDVQYTTQLGEEFYFLEG-GIPPVYDLVNWQIAPDGSLQYAFIGHVD-----GNQLSINDSAITWPGDSGKVPISVCTSECPPGTRKAIKKGLPVCCFDCLPCTEGEISNSTGSIKCYRCPKEFWSNSYKNECVARETEFLSVKETMGITLMSVAVSGAVMTTTVAVIFLYHRNTPIVKANNSELSFLLLLSLKLCFLCALVFVGQPSLWSCRIQQAAFGISFVLCISCILVKTFVVLIAFHSTRPESSALIKWFGLGKQRGIVLVFTCVQVVICAIWLCVSPPLPYQNFGMHRSKVILECTIGSVVGFTCVLGYIGFLATVCFLLAFFARKLPDNFNEAKYITFSMLIFCAVWVAFVPAYVSSPGKYSVVVEVFAILASSFGLLFCIFVPKCYIILLKPENNTKKFLMGKE--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 219, "similar_positions": 277, "identity": "24.83%" }, { "cls_id": "homologset.agr.MGI:1316714", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VHR9-1", "uniprot_id": "Q9VHR9_DROME", "id": "Q9VHR9-1", "name": "", "aln": "MQRNCFSLRPFLRGVGDVGAVCKPIREFRNSAALKYAAAAAAAPKTRPGKVPPKMVKLRKQFQADNDLPIFLKGGSMDNILYRLTWVLCFLGIGGDVWLWLGYIIA----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q6IHY5-1", "uniprot_id": "Q6IHY5_DROME", "id": "Q6IHY5-1", "name": "", "aln": "----------------------------------------MALPDGLSNKM--------KVFQAVNELPVFLKGGPADKILFGITAGLCGLGIVSFVHLVYTMGFAKKKA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0ABK0L816-1", "uniprot_id": "A0ABK0L816_RAT", "id": "A0ABK0L816-1", "name": "Cytochrome c oxidase subunit 7A1, mitochondrial", "aln": "--------------MPTLNPGSGVLDQVSQALIRSF----TSSTRSHLEN---RVAQKQKLFQADNDLPVHLKGGGMDNILYRLTMTLTLGGTAYCLYCLGWASFPHKK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P56392-1", "uniprot_id": "CX7A1_MOUSE", "id": "P56392-1", "name": "Cytochrome c oxidase subunit 7A1, mitochondrial", "aln": "--------------MRALR--------VSQALVRSF----SSSTRSHLEN---RVAEKQKLFQADNDLPVHLKGGGMDNVLYRLTMTLTLGGTAYCLYCLGWASFPHKK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P24310-1", "uniprot_id": "CX7A1_HUMAN", "id": "P24310-1", "name": "Cytochrome c oxidase subunit 7A1, mitochondrial", "aln": "--------------MQALR--------VSQALIRSF----SSTARNRFQN---RVREKQKLFQEDNDIPLYLKGGIVDNILYRVTMTLCLGGTVYSLYSLGWASFPRN--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q08CE7-1", "uniprot_id": "CX7A1_DANRE", "id": "Q08CE7-1", "name": "Cytochrome c oxidase subunit 7A1, mitochondrial", "aln": "--------------MRHLLG-------LPQLASRAF----STTVR-QMKN---RVPEKQKIFLEDNGLPVHIKGGTTDAILYRLTMTLTVVGTGYSLYWLLIAAMPKRKA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VHS2-1", "uniprot_id": "COX7A_DROME", "id": "Q9VHS2-1", "name": "Cytochrome c oxidase subunit 7A, mitochondrial", "aln": "--------------MMNLSR--AVVRSFATTAGRRS----AAVPKDQIEKGYFEIRKVQEHFQKKDGKPVFLKGSVVDNVLYRVTVALALVGIGGMGKLFYELSVPKKE-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : * : *:.:**. * :*: :* * * .. ", "identical_positions": 9, "similar_positions": 13, "identity": "8.18%" }, { "cls_id": "homologset.agr.MGI:1316715", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P35171-1", "uniprot_id": "CX7A2_RAT", "id": "P35171-1", "name": "Cytochrome c oxidase subunit 7A2, mitochondrial", "aln": "MLRNVLALRQIAQ--RTISTTSR--RHFEN-------------------KVPEK----QKLFQEDNGMPVHLKGGTSDALLYRATMLLTVGGTAYAIYMLAMAAFPKK--------------------QN---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P48771-1", "uniprot_id": "CX7A2_MOUSE", "id": "P48771-1", "name": "Cytochrome c oxidase subunit 7A2, mitochondrial", "aln": "MLRNLLALRQIAQ--RTISTTSR--RHFEN-------------------KVPEK----QKLFQEDNGMPVHLKGGASDALLYRATMALTLGGTAYAIYLLAMAAFPKK--------------------QN---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P14406-1", "uniprot_id": "CX7A2_HUMAN", "id": "P14406-1", "name": "Cytochrome c oxidase subunit 7A2, mitochondrial", "aln": "MLRNLLALRQIGQ--RTISTASR--RHFKN-------------------KVPEK----QKLFQEDDEIPLYLKGGVADALLYRATMILTVGGTAYAIYELAVASFPKK--------------------QE---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O60397-1", "uniprot_id": "COX7S_HUMAN", "id": "O60397-1", "name": "Putative cytochrome c oxidase subunit 7A3, mitochondrial", "aln": "MLWNLLALHQIGQ--RTISTASH--RHFKN-------------------KVPEK----QKLFQEDDGIPLYLKGGIADALLHRATMILTVGGTAYAIYQLAVASFPNKGVTSIIPAITWFTFIQLSMDQKSDK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A2R8Q5H6-1", "uniprot_id": "A0A2R8Q5H6_DANRE", "id": "A0A2R8Q5H6-1", "name": "Cytochrome c oxidase subunit 7A2, mitochondrial", "aln": "MFQHFLTLQQVSR--RQISSTVR--RHMAN-------------------KVPDK----QKLFQEANGVPVHLKGGVGDAVLYRATMSLTVVGTVCVIYELLKAAVPQK--------------------KA---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VHR9-1", "uniprot_id": "Q9VHR9_DROME", "id": "Q9VHR9-1", "name": "", "aln": "MQRNCFSLRPFLRGVGDVGAVCKPIREFRNSAALKYAAAAAAAPKTRPGKVPPKMVKLRKQFQADNDLPIFLKGGSMDNILYRLTWVLCFLGIGGDVWLWLGYIIA---------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : ::*: . : :.:. : *.: * *** * :* ** : :*:.**** * :*:* * * . * :: .. ", "identical_positions": 22, "similar_positions": 25, "identity": "16.54%" }, { "cls_id": "homologset.agr.MGI:1316717", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P20695-1", "uniprot_id": "IFRD1_RAT", "id": "P20695-1", "name": "Interferon-related developmental regulator 1", "aln": "MPKNKKRNAPHRG--GGGGGGSGAATSAATTGGPHRTVQPFSDEDASIETMSHCSGYSDPSSFAEDGPEVLDEEGTQEDLEYKLKGLIDLTLDKSAKTRQAALEGVKNALSSKVLYEFVLERRMTLTDSIERCLKKGKSDGQRAAAALASVLCIQLGPGLESEEILKTLGPILKKIICDGTASIQARQTCATCFGVCCFIATDDITELYSTLECLEGIFTKSYLKEKD-TNVPCSTPNTVLHISSLLAWTLLLTICP------ISEVKKKLELHFHKLPSLLSCDDVNMRIAAGESLALLFELARGMESDFFYEDMDSLTQMLRALATDGNKHRAKVDKRKQRSVFRDVLRAVEERDFPTETVKFGPERMYIDSWVKKHTYDTFKEALGSGMQYHLQTNEFLRNVFELGP-PVMLDAATLKTMKIPRFERHLYNSAAFKARTKARSKCRDKRADVGEFF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P19182-1", "uniprot_id": "IFRD1_MOUSE", "id": "P19182-1", "name": "Interferon-related developmental regulator 1", "aln": "MPKNKKRNAPHRG--GGGGGGSGAATSAATAGGPHRTVQPFSDEDASIETMSHCSGYSDPSSFAEDGPEVLDEEGTQEDLEYKLKGLIDLTLDKSAKTRQAALEGLKNALSSKVLYEFVLERRMTLTDSIERCLKKGKSDEQRAAAAVASVLCIQLGPGFESEEILKTLGPILKKIICDGAASIQARQTCATCFGVCCFIATDDITELYSTLECFENIFTKSYLKEKD-TNVTCSTPNTVLHISSLLAWTLLLTICP------INEVKKKLELHFHKLPSLLSCDDVNMRIAAGESLALLFELARGMESDFFYEDMDSLTQMLRALATDGNKHRAKVDKRKQRSVFRDVLRAVEERDFPTETVKFGPERMYIDSWVKKHTYDTFKEVLGSGMQYHLQTNEFLRNVFELGP-PVMLDAATLKTMKISRFERHLYNSAAFKARTKARSKCRDKRADVGEFL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00458-1", "uniprot_id": "IFRD1_HUMAN", "id": "O00458-1", "name": "Interferon-related developmental regulator 1", "aln": "MPKNKKRNTPHRGSSAGGGGSGAAAATAATAGGQHRNVQPFSDEDASIETMSHCSGYSDPSSFAEDGPEVLDEEGTQEDLEYKLKGLIDLTLDKSAKTRQAALEGIKNALASKMLYEFILERRMTLTDSIERCLKKGKSDEQRAAAALASVLCIQLGPGIESEEILKTLGPILKKIICDGSASMQARQTCATCFGVCCFIATDDITELYSTLECLENIFTKSYLKEKD-TTVICSTPNTVLHISSLLAWTLLLTICP------INEVKKKLEMHFHKLPSLLSCDDVNMRIAAGESLALLFELARGIESDFFYEDMESLTQMLRALATDGNKHRAKVDKRKQRSVFRDVLRAVEERDFPTETIKFGPERMYIDCWVKKHTYDTFKEVLGSGMQYHLQSNEFLRNVFELGP-PVMLDAATLKTMKISRFERHLYNSAAFKARTKARSKCRDKRADVGEFF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VQI5-1", "uniprot_id": "Q9VQI5_DROME", "id": "Q9VQI5-1", "name": "", "aln": "MPRRNKKSAAGRG--------------------------RTNDSNSEDESFDNVSVYSHMSEVASS---EATDELANERFEEKFEKALEQATEKSAQTRVQALQAICELLMHRYMPDFVEDRKMTLMDFVEKSIRRGKGQEQVWGARLAPLLVLQMGG---DEGISKAMNQFLLNTVQDKSVGFDARAKCCTAVGLLSFLGCEDVGELVHLMQSFEAIFAGSYLRGDDKTPVSVTAEAGTFHAEALNAWGLLLTLIPSGDFVSLMTTGQNMFPSIKKFLGLLQSTHLDVRMAAGETIALILESGRAHEEDFLEDDIAELSEAVKQLATDSHKYRAKRDRKAQRATFRDVLRYLEEDISPEISIRFGTESLTLDSWSIHHQYSAMCTVMGPGMTSQLQENEFIRDIFQLGPRPTNTGINGNAKVKPTKLERHLVNAAAFKARSITRGKNRDKRSAVVT--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:.:*:.:. ** .*.::. *::.: * **. *..*.. :* ::* :* *:: :: : :***:** **:.: : * : : :*: :*:*** * :*:.:::**.: * .* :*.:* :*:* .* * *::. :* : : * :..::** .*.*..*: .*:. :*: ** ::.:* **: ***: .* * * :: .:* .:* ** ****: * : . ::: ::*: .**.. .:::*:****::**::* .*. *.**: :*: .*:: :: ****.:*:*** *:: **:.****** :** * :::**.* : :*.* :* *.:: .:*.** :** ***:*::*:*** *. . .:* .::**** *:******: :*.* ****: * ", "identical_positions": 148, "similar_positions": 162, "identity": "32.24%" }, { "cls_id": "homologset.agr.MGI:1316721", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9NQ69-1", "uniprot_id": "LHX9_HUMAN", "id": "Q9NQ69-1", "name": "LIM/homeobox protein Lhx9", "aln": "--------------------------------MEIVGCRAEDNSCPFRPPAMLFHGISGGHIQGIMEEMER--------------------------------RSKTEARLAKGAQLNGRDAGMPPLSPEKP-------------ALCAGCGGKISDRYYLLAVDKQWHLRCLKCCECKLALESELTCFAKDGSIYCKEDYYRRFSVQRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSLVYCRAHFETLLQG-----------------------EYPPQLSYTELAAKSGGLALPYFNGTGTVQKGRPRKRKSPALGVDIVNYNSGCNENEADHLDRDQQPYPPSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQNARAKFRRNLLRQENGGVDKADGTSLPAPPSADSGALTPPGTATTLTDLTNPTITVVTSVTSNMDSHESGSPSQTTLTNLF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9WUH2-3", "uniprot_id": "LHX9_MOUSE", "id": "Q9WUH2-3", "name": "LIM/homeobox protein Lhx9", "aln": "--------------------------------MEIVGCRAENNSCPFRPPAMLFHGISGGHIQGIMEEMER--------------------------------RSKTEARLTKGTQLNGRDAGMPPLSPEKP-------------ALCAGCGGKISDRYYLLAVDKQWHLRCLKCCECKLALESELTCFAKDGSIYCKEDYYRRFSVQRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSLVYCRAHFETLLQG-----------------------EYPPQLSYTELAAKSGGLALPYFNGTGTVQKGRPRKRKSPALGVDIVNYNSGCNENEADHLDRDQQPYPPSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQNARAKFRRNLLRQENGGVDKADGTSLPAPPSADSGALTPPGTATTLTDLTNPTVTVVTTVTSNMDSHEPGSPSQTTLTNLF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q80W90-1", "uniprot_id": "LHX9_RAT", "id": "Q80W90-1", "name": "LIM/homeobox protein Lhx9", "aln": "---------------------------------MLNGTTLEA--------AMLFHGISGGHIQGIMEEMER--------------------------------RSKTEARLAKGTQLNGRDAGMPPLSPEKP-------------ALCAGCGGKISDRYYLLAVDKQWHLRCLKCCECKLALESELTCFAKDGSIYCKEDYYRRFSVQRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSLVYCRAHFETLLQG-----------------------EYPPQLSYTELAAKSGGLALPYFNGTGTVQKGRPRKRKSPALGVDIVNYNSGCNENEADHLDRDQQPYPPSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQNARAKFRRNLLRQENGGVDKADGTSLPAPPSADSGALTPPGTATTLTDLTNPTVTVVTTVTSNMDSHESGSPSQTTLTNLF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q1LWV4-1", "uniprot_id": "LHX9_DANRE", "id": "Q1LWV4-1", "name": "LIM/homeobox protein Lhx9", "aln": "--------------------------------MEVVGCKAKESSCTLRPAAMLFHGISGDHIQGIMEEMER--------------------------------RSKSESRLAKTVQMNGRETTMPSMSPEKP-------------ALCAGCGGKISDRYYLLAVDKQWHLRCLKCCECKLALESELTCFAKDGSIYCKEDYYRRFSVQRCARCHLGISASEMVMRARDSVYHLSCFTCTTCNKTLTTGDHFGMKDNLVYCRVHFETLIQG-----------------------EYHPQLNYAELAAKGGGLALPYFNGTGTVQKGRPRKRKSPAMGIDIGSYSSGCNENDADHLDRDQQPYPPSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQNARAKFRRNVLRQENGGVDKADGTSLP-PPSSDSGALTPPSTATTLTDLTNPSITVVTSVTSSLDSHESGSPPQTTLTNLF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P29673-1", "uniprot_id": "APTE_DROME", "id": "P29673-1", "name": "Protein apterous", "aln": "MGVCTEERPVMHWQQSARFLGPGAREKSPTPPVAHQGSNQCGSAAGANNNHPLFRACSSSSCPDICDHSTKPFGNAYGTESFRSYETADRATFEDSAAKFSISRSRTDCTEVSDETTSGISFKTEPFGPPSSPESTSDSKITRNLDDCSGCGRQIQDRFYLSAVEKRWHASCLQCYACRQPLERESSCYSRDGNIYCKNDYYSFFGTRRCSRCLASISSNELVMRARNLVFHVNCFCCTVCHTPLTKGDQYGIIDALIYCRTHYSIAREGDTASSSMSATYPYSAQFGSPHNDSSSPHSDPSRSIVPTGIFVPASHVINGLPQPARQKGRPRKRKPKDIEAFTANIDLNTEYVDFGRGSHLSSSSRTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLSQKTGLPKRVLQVWFQNARAKWRRMMMKQDG------------------SGLLEKGEGALDLDSIS----------VHSPTSFILGGPNSTPPLNLD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * **:. *.. .* :. : **:::. .. .* . .:.* .. *:*** :*.**:** **:*:** **:* *: .** * :*:::**.****:*** *..:**:** .**:.*:*****: *:*:.** *:.*:..**.**::*: * *:***.*:. :* . *: . :. . * :. . . .* * .* : * ** :.:. : * . ..*.:**********************************:*****.**************:** :::*:. ** * * * .:: . . *. *.* .*. ** ", "identical_positions": 148, "similar_positions": 102, "identity": "29.78%" }, { "cls_id": "homologset.agr.MGI:1316726", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P06399-1", "uniprot_id": "FIBA_RAT", "id": "P06399-1", "name": "Fibrinogen alpha chain", "aln": "-MLSLRVACLILSLASTVWTADTGTTSEFIEAGGDIRGPRIVER---QPSQCKETDWPFCSDEDWNHKCPSGCRMKGLIDEANQDFTNRINKLKNSLFDFQKNNKDSNSLTRNIMEYLRGDFANANNFDNTFGQVSEDLRRRIQILKRKVIEKAQQIQVLQKDVRDQLIDMKRLEVDIDIKIRSCKGSCSRSVSREINLKDYEGQQKQLEQVIAKDLLPAKDRQYLPAIKMSPVPDLVPGSFKSQLQEGPPEWKALTEMRQMRMELERPGKDGASRG-----------DLPGDSRGDS----ATRGPGSK-IENPMTPGHGGSGYWRPGSSGSGSDGNWGSGTTGSDDTGTWGAGSSRPSS------------------------------------------GSGNLKPSNPDWGEFSEFGGSSSPATRKEYHTGKLVTSKGDKELLIGNEKVTSTGTSTTRRSCSKTITKTVLGNDGHREVVKEVVTSDDGSDCGDGMDLGLTHSFSGRLDELSRMHPELGSFYDSR------FGSLTSNFKEFGSKT----SDSDIFTDIENPSSHVP---EFSSSSKTSTVRKQVT--------------KSYKMADEAASEAHQEGDTRTTKRG--RARTMRDCDDVLQTHPSGAQNGIFSIKLPGSSKIFSVYCDQETSLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLNDKGEGEFWLGNDYLHLLTLRGSVLRVELEDWAGKEAYAEYHFRVGSEAEGYALQVSSYQGTAGDALMEGSVEEGTEYTSHSNMQFSTFDRDADQWEENCAEVYGGGWWYNSCQAANLNGIYYPGGTYDPRNNSPYEIENGVLWVPFRGADYSLWAVRMKIRPLVGQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9PV24-1", "uniprot_id": "FIBA_MOUSE", "id": "E9PV24-1", "name": "Fibrinogen alpha chain", "aln": "-MLSLRVTCLILSVASTVWTTDTEDKGEFLSEGGGVRGPRVVER---HQSQCKDSDWPFCSDDDWNHKCPSGCRMKGLIDEANQDFTNRINKLKNSLFDFQRNNKDSNSLTRNIMEYLRGDFANANNFDNTYGQVSEDLRRRIEILRRKVIEKAQQIQALQSNVRAQLIDMKRLEVDIDIKIRSCKGSCSRAVNREINLQDYEGHQKQLQQVIAKELLPTKDRQYLPALKMSPVPDLVPGSFKSQLQEAPPEWKALTEMRQMRMELERPGKDGGSRG-----------DSPGDSRGDSRGDFATRGPGSK-AENPTNPGPGGSGYWRPGNSGSGSDGNRNPGTTGSDGTGDWGTGSPRPGS------------------------------------------DSGNFRPANPNWGVFSEFGDSSSPATRKEYHTGKAVTSKGDKELLIGKEKVTSSGTSTTHRSCSKTITKTVTGPDGRREVVKEVITSDDGSDCGDATELDISHSFSGSLDELSERHPDLSGFFDNH------FGLISPNFKEFGSKTH---SDSDILTNIEDPSSHVP---EFSSSSKTSTVKKQVT--------------KTYKMADEAGSEAHREGETRNTKRGRARARPTRDCDDVLQTQTSGAQNGIFSIKPPGSSKVFSVYCDQETSLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLNDKGEGEFWLGNDYLHLLTLRGSVLRVELEDWAGKEAYAEYHFRVGSEAEGYALQVSSYRGTAGDALVQGSVEEGTEYTSHSNMQFSTFDRDADQWEENCAEVYGGGWWYNSCQAANLNGIYYPGGTYDPRNNSPYEIENGVVWVPFRGADYSLRAVRMKIRPLVGQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P02671-1", "uniprot_id": "FIBA_HUMAN", "id": "P02671-1", "name": "Fibrinogen alpha chain", "aln": "-MFSMRIVCLVLSVVGTAWTADSGE-GDFLAEGGGVRGPRVVER---HQSACKDSDWPFCSDEDWNYKCPSGCRMKGLIDEVNQDFTNRINKLKNSLFEYQKNNKDSHSLTTNIMEILRGDFSSANNRDNTYNRVSEDLRSRIEVLKRKVIEKVQHIQLLQKNVRAQLVDMKRLEVDIDIKIRSCRGSCSRALAREVDLKDYEDQQKQLEQVIAKDLLPSRDRQHLPLIKMKPVPDLVPGNFKSQLQKVPPEWKALTDMPQMRMELERPGGNEITRGGSTSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATWKPGSSGPGSTGSWNSGSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSESSVSGSTGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGNVSPGTRREYHTEKLVTSKGDKELRTGKEKVTSGSTTTTRRSCSKTVTKTVIGPDGHKEVTKEVVTSEDGSDCPEAMDLG-TLSGIGTLDGFRHRHPDEAAFFDTASTGKTFPGFFSPMLGEFVSETESRGSESGIFTNTKESSSHHPGIAEFPSRGKSSSYSKQFTSSTSYNRGDSTFESKSYKMADEAGSEADHEG-THSTKRGHAKSRPVRDCDDVLQTHPSGTQSGIFNIKLPGSSKIFSVYCDQETSLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLNDEGEGEFWLGNDYLHLLTQRGSVLRVELEDWAGNEAYAEYHFRVGSEAEGYALQVSSYEGTAGDALIEGSVEEGAEYTSHNNMQFSTFDRDADQWEENCAEVYGGGWWYNNCQAANLNGIYYPGGSYDPRNNSPYEIENGVVWVSFRGADYSLRAVRMKIRPLVTQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B8A5L6-1", "uniprot_id": "B8A5L6_DANRE", "id": "B8A5L6-1", "name": "", "aln": "MKFTHSLLCLFVAVSSALAEEDTVV---------NPRGARPIEHGFKAQDTCQTKEWPGCTDDDWGSKCPSGCRVQGLMDKADHDLLKKIEKIRRLLVEGQKLYRSADEVSKTTYTYLREKLTSNSGYDNRYMSLAEQLRQRITDIKIKIDRQLRLLDALKSQVKDQVVVMQRLEVDIDIKLRTCKGSCASYSEFSVDRESYVTLDKQMDNLNAMRVQSVETVSSLGIMKSRPLKDVLVPTIYKSGTGKAEQKLLFGDVGQMQLSLEAEG--------------------STAESAATVSKFPTSGTGSTSQTSSKQCTKSVRKVITHTKDGPVEKVEVSSSGPGCDDLGKLGISDSEFLT------------------------------------------AAKDGKDLSRDGLKITVTGGDEKSLTSLSHSTSDLGGFGGDFFKNLGTDNRKYASSSSS------TSTKTVS--DGSKSYSKTTLTSDP------------------------IFGDDLGAFMRGD-------------------------------VEEDMPDIHAR----------------------------------SVKSQDDR--KAGFVG---------------GDCVEIQQKHVNGGQSGMFKIKPAGSEEVVEVYCDQSTGLGGWTLVQQREDGSVNFNRTWKEYLNGFGQIDKQGKGEIWIGNKFLHLLTQKESLLRVELQDWTGAEAYAEYNIKVGSEAEGFPLTASDYDGDAGDALVRGHPNLG-SFLSHAGMKFSTFDRDSDKWEENCAEMYGGGWWYNNCQSANLNGIYYKGGQYDPATKVPYEIENGVVWLPFKPADYSLKVVRMKIRPV---", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : **.::: .: *: . **.* :*: . *: .:** *:*:**. *******::**:*:.::*: ::*:*::. *.: *: :.:..:: . ** .::. .. ** : ::*:** ** :: *: .: : :: *:.:*: *:: *:*********:*:*:***: .:: :.* :**:::: * : . . . * :* *: *:: .: .. . : : :: **::.** * . . : *.**. .. . ..*. . . ... .* .. * . .... : : : : . : : ... .. * .: * . ** *.:: . .:::: * **** ** :. * .:**: : ..* .: . .. * : * *: :* * ** :: *.: .* *.*:*.** .**.::..*****.*.**** *:*** ***:******::* .***.::.:*:**:*:**.:***** : *:*****:**:* ******:::*******:.* .*.* * *****:.* : * .: ** .*:*******:*:*******:********.**:******** ** *** .: ********:*:.*: ***** .*******: ", "identical_positions": 242, "similar_positions": 231, "identity": "27.72%" }, { "cls_id": "homologset.agr.MGI:1316727", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q149F3-1", "uniprot_id": "ERF3B_MOUSE", "id": "Q149F3-1", "name": "Eukaryotic peptide chain release factor GTP-binding subunit ERF3B", "aln": "-MDLGSSS-DSAPDCWDQVDMEAPGSAPSGDGIAPAAMAAAEAAEAEAQR--KHLSLAFSSQLNIHAKPFVPSVSAAEFVPSFLPGSAQPPAPTASS----------CDETCIGGAGEPEGKRM--------EWGAPVEPSKDGPLVSWEGS--SSVVTMELSEPVVENGEVEMALEESWEL-KEVSEAKPEA-SLGDAGPPEESVKEVMEE--KEEVRKSKSVSIPSGA-------------------------PKKEHVNVVFIGHVDAGKSTIGGQIMFLTGMVDRRTLEKYEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETEKKHFTILDAPGHKSFVPNMIGGASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKYLIVLINKMDDPTVDWSSERYEECKEKLVPFLKKVGFSPKKDIHFMPCSGLTGANIKEQS--DFCPWYTGLPFIPYLDSLPNFNRSIDGPIRLPIVDKYKDMGTVVLGKLESGSIFKGQQLVMMPNKHSVEVLGIVSD-DAETDFVAPGENLKIRLKGIEEEEILPGFILCEPSNLCHSGRTFDVQIVIIEHKSIICPGYNAVLHIHTCIEEVEITALISLVDKKSGEKSKTRPRFVKQDQVCIARLRTAGTICLETFKDFPQMGRFTLRDEGKTIAIGKVLKLVPEKD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A096MJE3-1", "uniprot_id": "A0A096MJE3_RAT", "id": "A0A096MJE3-1", "name": "", "aln": "-MDLGSSS-DSAPDCWDQVDMEAPGSAPSGDEIAPAATAAAEAAEAEAQR--RHLSLAFSSQLNINAKPFVPSVSAAEFVPSFLPGSAQLPAPTASS----------CDETCIGGAAEPQGKRM--------EWGAPVEPSKDGPLVSWEGS--NSAVTMELSEPVVENGEVEMALEESWEL-KEVSEAAPEG-SLGDVGPPEESGKEVMEE--KEEIRKSKSVVRPSGA-------------------------PKKEHVNVVFIGHVDAGKSTIGGQIMFLTGMVDRRTLEKYEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETEKKHFTILDAPGHKSFVPNMIGGASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKYLIVLINKMDDPTVDWSSERYEECKEKLVPFLKKVGFSPKKDIHFMPCSGLTGANIKEQS--DFCPWYTGLPFIPYLDSLPNFNRSIDGPIRLPIVDKYKDMGTVVLGKLESGSIFKGQQLVMMPNKHSVEVLGIVSD-DAETDFVAPGENLKIRLKGIEEEEILPGFILCEPNNLCHSGRTFDVQIVIIEHKSIICPGYNAVLHIHTCIEEVEITALISLVDKKSGEKSKTRPRFVKQDQVCIARLRTAGTICLETFKDFPQMGRFTLRDEGKTIAIGKVLKLVPEKD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8IYD1-1", "uniprot_id": "ERF3B_HUMAN", "id": "Q8IYD1-1", "name": "Eukaryotic peptide chain release factor GTP-binding subunit ERF3B", "aln": "-MDSGSSSSDSAPDCWDQVDMESPGSAPSGDGVS--------SAVAEAQR--EPLSSAFSRKLNVNAKPFVPNVHAAEFVPSFLRGPTQPPTLPAGSGS--------NDETCTG-AGYPQGKRM--------GRGAPVEPSREEPLVSLEGS--NSAVTMELSEPVVENGEVEMALEESWEHSKEVSEAEPGGGSSGDSGPPEESGQEMMEE--KEEIRKSKSVIVPSGA-------------------------PKKEHVNVVFIGHVDAGKSTIGGQIMFLTGMVDKRTLEKYEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETERKHFTILDAPGHKSFVPNMIGGASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKHLIVLINKMDDPTVNWSIERYEECKEKLVPFLKKVGFSPKKDIHFMPCSGLTGANIKEQS--DFCPWYTGLPFIPYLDNLPNFNRSIDGPIRLPIVDKYKDMGTVVLGKLESGSIFKGQQLVMMPNKHNVEVLGILSD-DTETDFVAPGENLKIRLKGIEEEEILPGFILCDPSNLCHSGRTFDVQIVIIEHKSIICPGYNAVLHIHTCIEEVEITALISLVDKKSGEKSKTRPRFVKQDQVCIARLRTAGTICLETFKDFPQMGRFTLRDEGKTIAIGKVLKLVPEKD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VK85-1", "uniprot_id": "Q9VK85_DROME", "id": "Q9VK85-1", "name": "", "aln": "-MAAQENT--EISTKFSTLNVNAVEFVPSFSYNS-------VVNVAEEAA--AVVVAAAAAEETADPGPASGSATPATTPDSVGSGGSTAGAAPPPPTA--------QGAGAAAPSAQPPTSSS--------NSASPAPGSPATTPSAGAAA--ADPTPIDGLNPSDKIANNETDPADSWDVDDAVITPEDEE--------VEDAEFTEGEA--TPKVSKKKVVKVEENR-------------------------SKREHVNVVFIGHVDAGKSTIGGQIMSLTGMVDKRTLEKYEREAREKSRESWYLSWALDTNQEERDKGKTVEVGRAFFETDRKHFTILDAPGHKSFVPNMIGGAAQADLAVLVISARKGEFETGFDRGGQTREHAMLAKTAGVKHLVVLVNKMDDPTVNWDQTRYNECKDKILPYLKKLGFNPAKDLTFMPCSGLSGYGLKDQIPETLCPWYRGPAFIPFIDELPSLNRKSDGPFIMPIVDKYKDMGTVVMGKVESGTARKGQNLLVMPNRTQVAVDQLFSD-DFEVTSVGPGENVKIKLKGIEEEDVSPGFVLCDAANPIKTGKIFDAQVVILEHKSIICAGYSAVMHIHCAAEEVTVKALICLVDKKSGDKSKTRPRFVKQDQVAIMRIECSGMICLEQFKLFPQMGRFTLRDENKTIAIGKVLKVVE---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P05453-1", "uniprot_id": "ERF3_YEAST", "id": "P05453-1", "name": "Eukaryotic peptide chain release factor GTP-binding subunit", "aln": "MSDSNQGNNQQNYQQYSQNGNQQQGNNRYQGYQAYNAQAQPAGGYYQNYQGYSGYQQGGYQQYNPDAGYQQQYNPQGGYQQYNPQGGYQQQFNPQGGRGNYKNFNYNNNLQGYQAGFQPQSQGMSLNDFQKQQKQAAPKPKKTLKLVSSSGIKLANATKKVGTKPAESDKKEEEKSAETKEPTKEPTKVEEPVKKEEKPVQTEEKTEEKSELPKVEDLKISESTHNTNNANVTSADALIKEQEEEVDDEVVNDMFGGKDHVSLIFMGHVDAGKSTMGGNLLYLTGSVDKRTIEKYEREAKDAGRQGWYLSWVMDTNKEERNDGKTIEVGKAYFETEKRRYTILDAPGHKMYVSEMIGGASQADVGVLVISARKGEYETGFERGGQTREHALLAKTQGVNKMVVVVNKMDDPTVNWSKERYDQCVSNVSNFLRAIGYNIKTDVVFMPVSGYSGANLKDHVDPKECPWYTGPTLLEYLDTMNHVDRHINAPFMLPIAAKMKDLGTIVEGKIESGHIKKGQSTLLMPNKTAVEIQNIYNETENEVDMAMCGEQVKLRIKGVEEEDISPGFVLTSPKNPIKSVTKFVAQIAIVELKSIIAAGFSCVMHVHTAIEEVHIVKLLHKLEKGTNRKSKKPPAFAKKGMKVIAVLETEAPVCVETYQDYPQLGRFTLRDQGTTIAIGKIVKIAE---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ... . :. . : . : : . : . .. . * . . . * . :. . : . . . :* . : * :: : . *: * .: .: . .. ::**.::*:*********:**::: *** **:**:*******:: .*: *****.:***:***:.***:***:*:***:::::********* :*.:*****:***:.**********:****::********:**** **: ::*::********:*. **::* .:: :*: :*:. .*: *** ** :* .:*:: **** * .:: ::* : .:* :.*: :**. * **:**:* **:*** ***. ::***: * : : .: : *. . **::*:::**:***:: ***:* .. * :: * .*:.*:* ****..*:..*:*:* . *** : *: ::* :. ***. * *.*:. * :. . :*:* :: :**:*******:..******::*:. ", "identical_positions": 209, "similar_positions": 184, "identity": "30.38%" }, { "cls_id": "homologset.agr.MGI:1316728", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AYD5-1", "uniprot_id": "Q6AYD5_RAT", "id": "Q6AYD5-1", "name": "", "aln": "MDPSSGGGGGGGGGGGGSSSSSSDSAPDCWDQTDMEAPGPGPCGGG-----SMAAVAEAQRENLSAAFSRQLNVNAKPFVPNVHA-----AEFVPSFLRGPAQPPLSPAGAAGGDHGAGSSAGGPSEPVESSQEQSLCEGSNST---VSMELSEPVVENGETEMSPEESWEHKEEISEAEPA-------GGGSSGDGRPPEESTQEMMEEEE--EIPKPKSVVAPPGAP----------------------------KKEHVNVVFIGHVDAGKSTIGGQIMYLTGMVDKRTLEKYEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETEKKHFTILDAPGHKSFVPNMIGGASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKHLIVLINKMDDPTVNWSNERYEECKEKLIPFLKKVGFNPKKDIHFMPCSGLTGANLKEQS--DFCPWYIGLPFIPYLDNLPNFNRSVDGPIRLPIVDKYKDMGTVVLGKLESGSICKGQQLVMMPNKHNVEVLGILSD-DVETDSVAPGENLKIRLKGIEEEEILPGFILCDLNNLCHSGRTFDAQIVIIEHKSIICPGYNAVLHIHTCIEEVEITALICLVDKKSGEKSKTRPRFVKQDQVCIARLRTAGTICLETFKDFPQMGRFTLRDEGKTIAIGKVLKLVPEKD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R050-1", "uniprot_id": "ERF3A_MOUSE", "id": "Q8R050-1", "name": "Eukaryotic peptide chain release factor GTP-binding subunit ERF3A", "aln": "MDPSSGGGGGGGGGG---SSSSSDSAPDCWDQTDMEAPGPGPCGGGGSGSGSMAAVAEAQRENLSAAFSRQLNVNAKPFVPNVHA-----AEFVPSFLRGPAQPPLSPAGAAGGDHGAGSGAGGPSEPVESSQDQS-CEGSNST---VSMELSEPVVENGETEMSPEESWEHKEEISEAEP--------GGGSSGDGRPPEESTQEMMEEEE--EIPKPKSAVAPPGAP----------------------------KKEHVNVVFIGHVDAGKSTIGGQIMYLTGMVDKRTLEKYEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETEKKHFTILDAPGHKSFVPNMIGGASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKHLIVLINKMDDPTVNWSNERYEECKEKLVPFLKKVGFNPKKDIHFMPCSGLTGANLKEQS--DFCPWYIGLPFIPYLDNLPNFNRSVDGPIRLPIVDKYKDMGTVVLGKLESGSICKGQQLVMMPNKHNVEVLGILSD-DVETDSVAPGENLKIRLKGIEEEEILPGFILCDLNNLCHSGRTFDAQIVIIEHKSIICPGYNAVLHIHTCIEEVEITALICLVDKKSGEKSKTRPRFVKQDQVCIARLRTAGTICLETFKDFPQMGRFTLRDEGKTIAIGKVLKLVPEKD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P15170-1", "uniprot_id": "ERF3A_HUMAN", "id": "P15170-1", "name": "Eukaryotic peptide chain release factor GTP-binding subunit ERF3A", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------MELSEPIVENGETEMSPEESWEHKEEISEAEP--------GGGSLGDGRPPEESAHEMMEEEE--EIPKPKSVVAPPGAP----------------------------KKEHVNVVFIGHVDAGKSTIGGQIMYLTGMVDKRTLEKYEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETEKKHFTILDAPGHKSFVPNMIGGASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKHLIVLINKMDDPTVNWSNERYEECKEKLVPFLKKVGFNPKKDIHFMPCSGLTGANLKEQS--DFCPWYIGLPFIPYLDNLPNFNRSVDGPIRLPIVDKYKDMGTVVLGKLESGSICKGQQLVMMPNKHNVEVLGILSD-DVETDTVAPGENLKIRLKGIEEEEILPGFILCDPNNLCHSGRTFDAQIVIIEHKSIICPGYNAVLHIHTCIEEVEITALICLVDKKSGEKSKTRPRFVKQDQVCIARLRTAGTICLETFKDFPQMGRFTLRDEGKTIAIGKVLKLVPEKD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VK85-1", "uniprot_id": "Q9VK85_DROME", "id": "Q9VK85-1", "name": "", "aln": "-----------------MAAQENTEISTKFSTLNVNAVEFVPSFSYN----SVVNVAEEAAAVVVAAAAAEETADPGPASGSATP-----ATTPDSVGSGGSTAGAAPPPPT--AQGAGAAAPSAQPPTSSSNSASPAPGSPAT---TPSAGAAAADPTPIDGLNPSDKIANNETDPADSWD-------VDDAVITPEDEEVEDAEFTEGEATPKVSKKKVVKVEENRS----------------------------KREHVNVVFIGHVDAGKSTIGGQIMSLTGMVDKRTLEKYEREAREKSRESWYLSWALDTNQEERDKGKTVEVGRAFFETDRKHFTILDAPGHKSFVPNMIGGAAQADLAVLVISARKGEFETGFDRGGQTREHAMLAKTAGVKHLVVLVNKMDDPTVNWDQTRYNECKDKILPYLKKLGFNPAKDLTFMPCSGLSGYGLKDQIPETLCPWYRGPAFIPFIDELPSLNRKSDGPFIMPIVDKYKDMGTVVMGKVESGTARKGQNLLVMPNRTQVAVDQLFSD-DFEVTSVGPGENVKIKLKGIEEEDVSPGFVLCDAANPIKTGKIFDAQVVILEHKSIICAGYSAVMHIHCAAEEVTVKALICLVDKKSGDKSKTRPRFVKQDQVAIMRIECSGMICLEQFKLFPQMGRFTLRDENKTIAIGKVLKVVE---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P05453-1", "uniprot_id": "ERF3_YEAST", "id": "P05453-1", "name": "Eukaryotic peptide chain release factor GTP-binding subunit", "aln": "-MSDSNQGNNQQNYQQYSQNGNQQQGNNRYQGYQAYNAQAQPAGGYYQNYQGYSGYQQGGYQQYNPDAGYQQQYNPQGGYQQYNPQGGYQQQFNPQGGRGNYKNFNYNNNLQGYQAGFQPQSQGMSLNDFQKQQKQAAPKPKKTLKLVSSSGIKLANATKKVGTKPAESDKKEEEKSAETKEPTKEPTKVEEPVKKEEKPVQTEEKTEEKSELPKVEDLKISESTHNTNNANVTSADALIKEQEEEVDDEVVNDMFGGKDHVSLIFMGHVDAGKSTMGGNLLYLTGSVDKRTIEKYEREAKDAGRQGWYLSWVMDTNKEERNDGKTIEVGKAYFETEKRRYTILDAPGHKMYVSEMIGGASQADVGVLVISARKGEYETGFERGGQTREHALLAKTQGVNKMVVVVNKMDDPTVNWSKERYDQCVSNVSNFLRAIGYNIKTDVVFMPVSGYSGANLKDHVDPKECPWYTGPTLLEYLDTMNHVDRHINAPFMLPIAAKMKDLGTIVEGKIESGHIKKGQSTLLMPNKTAVEIQNIYNETENEVDMAMCGEQVKLRIKGVEEEDISPGFVLTSPKNPIKSVTKFVAQIAIVELKSIIAAGFSCVMHVHTAIEEVHIVKLLHKLEKGTNRKSKKPPAFAKKGMKVIAVLETEAPVCVETYQDYPQLGRFTLRDQGTTIAIGKIVKIAE---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .* :. ::* . . . : * . :: . * . ::**.::*:*********:**::: *** *****:*******:: .*: *****.:***:***:.***:***:*:***:::::********* :*.:*****:***:.**********:****::********:**** **::::*::**********.: **::* .:: :*: :*:* .*: *** ** :* .**:: **** * .:: ::* : .:* :.*: :**. * **:**:* **:*** ***. ::***: * : : .: : *. . **::*:::**:***:: ***:* . * :: * **:.*:* ****..*:..*:*:* . *** : *: ::* :. ***. * *.*:. * :. . :*:* :: :**:*******:..******::*:. ", "identical_positions": 212, "similar_positions": 152, "identity": "30.77%" }, { "cls_id": "homologset.agr.MGI:1316729", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZB66-1", "uniprot_id": "D3ZB66_RAT", "id": "D3ZB66-1", "name": "", "aln": "MFIFMVVFFLIN-IPLLMANVIDP--------RCFLRIN------LDEVKDGDLQSTCSFILEAVQIPMEKDYFN---QTLNVLKTAKNHKYALTLAFSIDEINRNPDLLPNMSLIIKYSFGYCDGKTVTPTPYLFHEEFEKPIPNYFCKEETKCTFLLTGPHWGTSLLFLTKLDIFSSPRFLQLTYGPFHSTLNDNEQFPYLYQMAPKDTSLALAIVSFILYFNWNWVGLFISDEDQGNRFLSELKKVSESKKICFAFVSMISFSELLFHHKVEMYYDQIVMSSTSVIIIYGEGNSITELNFRIWESPVKHRIWVTTKQWN--FPTSNRDLTHDTFYGTFTFQHHHGEISGFNNLVQTWYQLRSTDLCQVMPDWK-YLNYEGSASNCEILENYTSGASLEWLLEQKFDMAFS---DDSYNIYNAVYAMAHAFHELNLQQVDNQAIDNEKGASSHCLKLN-----SFLRKTHFTNPLGDKVIMKQREILQEDYDIFHTQYFSEHLGIKVKIGKVSQYFKRDQHFHLYVDMIELATGSKKMPSSVCTEDCGPGFRRIWKEGMAACCFVCKPCPENEISNDTNMDQCMNCPEYQFANTKHNKCIQKGVLFLSYEDPLGMALALIAFCFSAFTAVVLWVFVKHHDTPIVKANNRNLSYLLIISLMFCFLCTFFFIGHPNRATCILQQITFGIVFTVAVSTVLAKTATVVLAFKVTDP-GRRLRNVLVSGTPNYIIPICSLFQCILCAIWLAVSPPFVDIDDYSEHGHIIIVCNKGSVTAFYCVLGYLACLALGSFTVAFLAKNLPDTFNEAKFLTFSMLVFCSVWVTFLPVYHSTKGKVMVAVEIFSILASSAGMLGCIFAPKIYIILMRPDRN-ILKFREKSYF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3ZVB5-1", "uniprot_id": "D3ZVB5_RAT", "id": "D3ZVB5-1", "name": "G-protein coupled receptors family 3 profile domain-containing protein", "aln": "MFILMEVFFFFLNIPLLMANFIDP--------KCFWRVN------LNEVKDKDLSITCSFILEAVQMPTENDYFN---QTLNILKTTKNHKYALALAFSIDEINRNPDLLPNMSLIIKYPLGLCDGQTTLPTPYLFNEIYFRPIPNYFCNEETMCTFLLTGPHWITSYSFWIHLNIFLSPSFLQLTYGPFHSTFSDNEQFPYLYQMNPKDTSLALAMVSFLLYFKWNWVGLVISDDDQGNQFLSELKKESKIKEICFAFVSMLAIDEISFYHKTEMYYNQIVMSSTNVIIIYGKTESIIELSFRMWESPVIQRIWVTTKEMN--FPTSKRDLTHDTFYGTLTFLHSHGEISGFKNFVQTWYHLRITDLHLVMPEWK-YFNYEASASNCKILKNYSSSASLEWLMEQTFDMVFS---DGSRDIYNAVNAMAHALHEMNLHLVDNQAIDNGKGASSHCFKIN-----SFLRKTHFTNPLGDRVIMKEREILQEDYNIFHTWNFSQHIGFKVKIGKFSPYFPHGRHFHLYVDMIELATGSRKMPSSVCTEDCSPGYRRFWKEGMAACCFVCSPCPENAISNETNMDQCVNCPEYQYANTKRDKCIQKNVMFLSYKDPLGMTLAFIAFFFSALTAVVLRVFVKHHDTPIVKANNRILSYLLITSLLFCFLCSFFFIGHPNRATCILQQITFGIVFTVAISTILAKTITVVLAFKVTNP-GRRLRNFLVLGTLNYIIPICSLFQCILCAIWLAVSPPFVDTDEHTEYGHIIIVCNKGSVTAFYCVLGYLACLALASFTVAFLAKNLPDTFNEAKFLTFSMLVFCSVWVTFLPVYHSTKGKIMVAVEIFSILASSAGMLGCIFAPKIYIILMRPERNAIQKIREKSYF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "K7N5W1-1", "uniprot_id": "K7N5W1_MOUSE", "id": "K7N5W1-1", "name": "", "aln": "MFIFMGVFFLLN-ITLLMANFINP--------RCFWRIN------LDEITDEYLGLSCTFILAAVQTPTEKDYFN---KTLNVLKTTKNHKYALALVFAMDEINRNPDLLPNMSLIIRYTLGLCDGKTVTPTPYLFHKKKQSPIPNYFCNEETMCSFLLSGPKWDVSLSFWMYLDSFLSPRILQLTYGPFHSIFSDDEQYPYLYQMAPKDTSLALAMVSFILYLKWNWIGLVIPDDDQGNQFLLELKKQSENKEICFAFVKMISVDDTSFPHKTEMDYNQIVMSSTNVIIIYGETRNFIYLIFRMWEPPILQRIWITTKQLN--FPTRKTDISHGTFYGSLTFLPHHGEISGFKKFVQTWFHVRNTDLYLVMPEWN-YFNYVSSASNCKILKNNSSDASFDWLMEQKFDMTFS---ENSHNIYNAVHAIAHALHEMNLQQADNQAIGNGKGASSHCLKVN-----SFLRRTYFTNPLGDKVFMKQRVIMQDEYDIIHFGNLSQHLGIKMKLGKFSPYLPHGRHSHLYVDMIELATGRRKMPSSVCSADCSPGFRRLWKEGMAACCFVCSPCPENEISNETNMDQCVNCPEYQYANTEQNKCIQKGVTFLSYEDPLGMALALMAFCFSAFTAVVLCVFVKHHDTPIVKANNRSLSYLLLMSLMFCFLCSFFFIGLPNRAICVLQQITFGIVFTVAVSTVLAKTVTVVLAFKVTDP-GRRLRNFLVSGTPNYIIPICSLLQCVLCAIWLAVSPPFVDIDEHTLHGHIIIVCNKGSDTAFYCILGYLACLALGSFSLAFLAKNLPDTFNEAKFLTFSMLVFCSVWVTFLPVYHSTKGKHMVAVEIFSILASSAGILGCIFVPKIYIILMRPERNSTQKIREKSYF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1QSW4-1", "uniprot_id": "F1QSW4_DANRE", "id": "F1QSW4-1", "name": "", "aln": "MSIHVLSWLTLSVPVLLLWPVCGSGTEVTPLETCVYLITPQYSDELGTYQDGDVIIGGLINLHNLAATPDLSFTRKPGLAQCLEFQERTYRWFQAIVFTVEEINQHPSLLP------GVKLGYHIMDSCSRYPHSLTAAMSMISGGNKTCGPTKPAKLLIGD--SSSTQSILLSTTLVPLKIPMISYLAGCPCLSDRQKYPNFFRTIPSDFYQARTMVQIAKRFGWTWIGAVIADSDNGHGTLQALEEEIKGTGICLAFYHTLYRER--LQKDVAFAARTVQASSARVILVLAWYTDVEAFLLELMRRNVTDRLFLASEIWSTSYNIMANPQLYTISKGTLGVALRSAPIPGFSAHLQQLHPSRYPEDKFLRTLWENTFGCSPTISSSKIIQNSLPPCSGRESLEGHIEFIDTSHLTVSYNIYLAVYAAAHALHSLLECNSQNHTDSKIKPKCSSPDNITPAQLLQHVKDVQYTTQLGEEFYFLEG-GIPPVYDLVNWQIAPDGSLQYAFIGHVD-----GNQLSINDSAITWPGDSGKVPISVCTSECPPGTRKAIKKGLPVCCFDCLPCTEGEISNSTGSIKCYRCPKEFWSNSYKNECVARETEFLSVKETMGITLMSVAVSGAVMTTTVAVIFLYHRNTPIVKANNSELSFLLLLSLKLCFLCALVFVGQPSLWSCRIQQAAFGISFVLCISCILVKTFVVLIAFHSTRPESSALIKWFGLGKQRGIVLVFTCVQVVICAIWLCVSPPLPYQNFGMHRSKVILECTIGSVVGFTCVLGYIGFLATVCFLLAFFARKLPDNFNEAKYITFSMLIFCAVWVAFVPAYVSSPGKYSVVVEVFAILASSFGLLFCIFVPKCYIILLKPENNTKKFLMGKE--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * : :: : **: . .. *. :. *. * : : * : . : .: . : : :.::: ::.*:::***::*.*** :* .: *: : . * : ** * * : . : ::* . . :.* :::* ::: *.* * ::*.: : *.*:* .*.*.*:*: * *:: : . **:** : . : :.. : : **: **:: . .. : :.: . : .*:::::: . : : *:: . . *.**. :* . * .: : . *: :. : *..:*::* . .* :* ::: : * :** ** * ***:*.: :*:: .: * .* ::. ..:: . :*. **:.. : : : *::.: .: :*:.. ..: : . * . . *:* ***: :* ** *: *:*:..*** * **.*. ***.*. :* .**: ::*: :::*: : . *** ::.:*::* :*. :.:*:.* :*: *::******** **:**: ** :****::.*:* *. * :** :*** *.:.:* :*.** .*::**: * * . * : : *. . *: : : .* ::*****.****: : .::*: *. ** ..* *:***:. ** .* :**:*::***.*****::*****:**:***:*:*.* *: ** *.**:*:***** *:* ***.** ****::*:.* : *. ", "identical_positions": 228, "similar_positions": 287, "identity": "25.85%" }, { "cls_id": "homologset.agr.MGI:1316730", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8M9PFV7-1", "uniprot_id": "A0A8M9PFV7_DANRE", "id": "A0A8M9PFV7-1", "name": "", "aln": "-----------------MLLYLCTLLLFFKLKVSVG---NASCKIMGEPKYPLLFKDGDVTIGALFPVHSIETAPSFEFTQKPQLLSCS-SVNLRDFRLAQILIFAIEEINRSESLLPKLSLGYKIYDTCSSKLSSMSATMALMNSFEFAGRDK--CNGQTSVHAIIGETESSATVILTRTTGPFKIPVISHAASCECLSSRKEYPSFFRTISSDYHQGRALAYIVKHLGWSWVGAVNSDNDYGNYGMAIFLNTAHKEGICVEYSEKFYR--TEPE-KLKKVVDTIKKSTAKVIVAFISFLEMRLLVEQLSAENITGLQIVGVEGWTTSKSLITPKTLNVLRGSLGFAMRKIYIEGFAEYVL-------------KPFWDTAFPC-IPNQRNDSWVILNCSRYQDLLVLKNYIEDVPEHRFSINVYNAVYAVAHALHSLFK------CKEQEGCEKDLLTQPQQVVDALKKVNFTVKMGDRVWFDSTGATLAQYEVVNWQQNSDGSVNFKKVGYYDASLPPDQRFVLNIKEILWAGGNLKKPRSVCSESCPPGTRKAAQKGRPICCYDCIPCADGEISNDT-DSNNCKQCQGEYWSNADKNKCVQKSVEFLSFTEVMGIVLVFFSLFGAGLTVLVAILFYSKKDTPIVKANNSELSFLLLFSLTLCFLCSLTFIGQPTQWSCMLRHTAFGITFVLCISCVLGKTLLVLMAFKATLP-GSNIMKWFGPVQQRLSVLAFTFIQVLICVLWLSISPPFPHKNMKYYEEKIILECSLGSTIGFWAILGYIGLLAALCFILAFLARTLPDNFNEAKFITFSMLIFCAVWITFIPAYVSSPGKFTVAVEIFAILSSSISLLLCIFAPKCYIILLKPEQNTKQYMLGKTTSKFY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M3B2Z8-1", "uniprot_id": "A0A8M3B2Z8_DANRE", "id": "A0A8M3B2Z8-1", "name": "", "aln": "-----------------MLLFLYSVLSLYHLNTKAE---NTLCQMIGNPKYPLLSKDGDITIGALFVIHSEVSLPSFAFTQKPNLLSCS-SLNIKDFRLAQTMIFAIEEINKNTNLLPNISVGYQIYDTCGSRFHSMSATMALMNGPKNSEGYT--CNEQSSVHAIVGETESSNTIILSRTTGPFKIPVISPTATCECLSNRKEFPSFFRTIASDYHQSRALAYIVKHFGWTWVGAVNSDNDYGNNGMATFQKTAKEVQICVEYSVKFIR--TETE-KIRNVVNVIKKGTAKVIVAFLTGFEMKSLLEQLSSQNITGLQMIGVEAWITSKTLITSKSFHVLGGSLGFAVRKIQIEGFADYVM-------------KAFWDTAFQS-FSN------ADLNYSQYQDLLLVKNYNEDVLEQRFVSYVYKAVYALAHSLHSLLR------CTEQGGCGKALTIQPHQLVEALRKVNFTVKMGDQVWFDSTGGVIAQYDVVNWQQNSDGSVQFQSVGYYDASLSPDQRFMLNTEKIVWAGGQLEKPRSVCSESCPPGTRKASQKGRPVCCHDCIPCADGEISNET-DSNNCKQCPGEYWSNANKNKCVTKAVEFLSFTEVMGIILVFFSLFGAGLTVLVAILFYSKKDTPIVKANNSELSFLLLFSLTLCFLCSIPFIGRPTQWSCMLRHTAFGITFVLCISCILGKTIVVLMAFKATLP-GSNIMKWFGPVQQRLSVLAFTLIQGLICVIWLTKSPPFPYKNMKYFQEQIILECSVGSTIGFWAVLGYIGLLAVLCFILAFLARTLPDNFNEAKFITFSMLIFCAVWITFIPAYVSSPGKLTVAVEIFAILASSFGLLFCIFAPKCYIILLQPEQNTKQQMMAKTPSKI-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9PPM0-1", "uniprot_id": "A0A8M9PPM0_DANRE", "id": "A0A8M9PPM0-1", "name": "", "aln": "-----------------MSVFFCTLLIFFQLYAKAE---KPICIMMGDPKYPLLSKEGDISIGAVFPVHSIETLPLFKFTQKPQLLSCS-SVSIRDFRMAQIMAFAIEEINRNESLLPNVSLGYQIYDTCGSGLSLMGANMALMNVQEFASRGS--CNGQSPVHAIIGETESSNTVILSRTTGPFKIPVISPSASCECLSNRKEYPYFFRTIASDYHQSRALAYIIKYFGWSWVGAVNSDNDYGNHGMAIFLSTAEKEGVCVEYSVKFQR--TEPE-KLKKVVDTIKKGTSKVIVAFLTEFEMKNLLEYLIIQNVTGLQVIGVEAWITANSMIKPNSFHVLGGSLGFAVKKLNIEGFEDYVT-------------KAFWETAFPCSQTSQKENSQYKLICNIYRDLLVLKNDNKDVPEQRYASNVYKAVYAVAHSLHNILK------CRENGACETDMKIQPQQVVEALRKVNFTIKMGDCVWFDSTGAVVAQYEVVNWQPDYNGSIQFKPVGYYDASLPPNQRFVINTENIIWAGGQLKKPRSVCSENCPPGTRKAVQKGRPVCCYDCIPCAEGEISNET-DSNNCKQCPGEYWSNAEKNKCVLKAVEFLSFKELMGIVLVFFSLLGAGLTTLVAILFYSKKDTPIVKANNSELSFLLLFSLMLCFLCSLTFIGRPTEWSCMLRHTAFGITFVLCISCVLGKTIVVLMAFKATLP-GSDVMKWFGPIQQRLSVLVITIVQVLICVLWLAVSPPLPYKNTKYFKEKIILECSLGSTIGFSAALGYIGLLAILCFILAFLARTLPDKFNEAKFITFSMIIFCAVWITFIPSYLSSPGKLTVAVEIFAILASSFGLLFCIFLPKCYIIMCKPEQNTKLHIIGKLNK---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9PAH3-1", "uniprot_id": "A0A8M9PAH3_DANRE", "id": "A0A8M9PAH3-1", "name": "", "aln": "-------------MTKKSELLLLMVLVTHGICVPNL---AQVCRLLGQPALPLLSEERNINIGAIFSLHKSALLKSHNFTSKPKQTTCG-GLNLREFKFVQTLIFAIEEINN-SSLLPGASLGYKIYDSCGSVAQAIFSGMALMNGYEETLSDTS-CSTPPAVHAIVGESNSSPTIGLASVVGPFSLPLVSHFATCSCLSNRKRFRTFFRTIPSDYYQSRALAQLVKHFGWTWVGTVRSRSDYGNNGIATFEEAAKQEGICIEYSEAVFK--TDPEVQFLKTIEVIKKATTKVVVAFMAFGDFVLLLKVMAQQNITGIQWIGSESWITSRNLAETKEYHFLSGAVGFAIANSKPVGLREFLMNVHPDKELNNELLKEFWETVFLCSFRNS-----SSGGCTGSEKLSELQNEYTDFSELRIENKVYTAVYAVAHSLHNVLKG-----FKFFTNSSKKQLPTPQKVLEYLRDVNFTVNTNENIFFDASGDPVARYDLVNWQPTKDGSLQFKLVGIYDSSLPSEQRLQINQESMLWAGNSGQLPVSVCSESCPPGTRKAVQKGRPICCYDCIPCAEGEISNYT-DSSDCFPCGLEYWSNESKDRCVLKVIEFLSYTEIMGVGLCIFSFIGVLLTATVSFLFYFYKETPIVRANNSELSFLLLFSLTLCFLCSLTFIGRPTDWSCMLRHTAFGITFVLCISCVLGKTIVVLMAFRATLP-GSNVMKWFGPLQQRLSVVSLTLIQVIICVLWLTMSPPFPFLNLSYYREKIILECNLGSAFGFWAVLGYTGLLSTLCFVLAFFARKLPDNFNEAKFITFSMLIFCAVWLTFIPAYVSAPGKYTVAVQLFAILASSFGLLFCIFAPKCYIILLKPEKNTKKQMMGKS-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0T300-1", "uniprot_id": "A0T300_DANRE", "id": "A0T300-1", "name": "", "aln": "--------------MANTLSLLLLLLLLHGHFLPAT---VQICDLVGQSALPVLSAERDINIGAIFSIHRNALLRLYPFTSKPEPTTCV-RLNLREFKFAQTFIFAIEEINNNTQLLPGVTLGYKIYDACNAISPTLVSGMALINGYENTLSDTS-CSQPPAVQAIVGESSSSPTTALAALVGPFNIPVISHFATCACLSNRKRYPSFFRTIPSDYYQSRALAQLVKHFGWTWVGTVRSRSDYGNNGITAFEDAAKQEGICIEYSEAILR--TDPQEQFRKTVEVIKKGTSKVVVAFISFGDFAPLVKVIAENNITGLQWVGSESWITSRNLAETKEYSFLSGAVGFAIVNAKLVGLKEFLVNVHPDQEPKNKLLKEFWETAFQCSFSNS-----DSALCTGSEKLGELKNEYTDVSELRIEHKAYAAVYAVAHTLHNVFKD-----VKAPNNS-KRELPTPQKVLQYMRNLSFTIKTGENIFFDASGDPVARYDLVNWQTAEDGSLQFKHVGIYDSSLPSKQRLQVNQEIMLWAGKSGLLPLSVCTESCLPGTRKAVQKGRPVCCYDCIPCAEGEISNST-DSSDCFSCDLEYWSNEKKDRCILKVVEFLSYAEIMGIILCIVSFIGLLLTVMVTCLFYLHKETPIVRANNSELSFLLLFSLSLCFLCSLTFIGRPTQWSCMLRHTAFGITFILCISCVLGKTIVVLMAFRATLP-GSNVMKWFGPLQQRLSVVSLTLVQVIVCLLWLTLSPPYPYMNLSYYREKIILECNLGSAFGFWAVLGYTGLLSTLCFVLAFLARKLPDNFNEAKFITFSMLIFCAVWLTFIPAYVSSPGKYTVAVEIFAILVSSFGLLFCIFAPKCYIILLKPEKNTKKQMMGKL-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8N7TDV0-1", "uniprot_id": "A0A8N7TDV0_DANRE", "id": "A0A8N7TDV0-1", "name": "", "aln": "MRISLGWVVCLVKEMHVNLLLILTLLCIRRLFPAVCGVHLGTCILQGDPQPPSLFSKGDFVIGGTFTIHYYLRTEKRTYTVRPQPLMCSGSMDFRELRFARVLQFAIQEINNSSNLLPGITLGYHIYDSCASVPMVIKVAVQLANGLQLAFNDTDSCAQSSEVLALVGESGSTAAITTSRLFGPFGIPQVSHYATCACLSDKRQHPTFFRTIPSDHHQAAALARMVKRFGWTWIGAVRSDSDYGNNGMASFLKAAEVEGICVEYSEAYYR--TQTRNKLQRVADVIRRSTARVIVAFMAAGDMRFLLEELSQQPPPPMQWIGSEAWVTDPQMLR---FNLSIGAVGFAIPRSVIPGFRKFLLDLSSEQALKIPVLKEFWESSFGCSLKQHTGYFSGMPACDGTEDLGTLKNPYTDTSQLRISNMVYKATYAIAHALHGIVC--------NGKLCDKNIKVEPRKVSDQLKQVNFSKNN-YSVSFDANGDPVAVYELVNWQLQGDGSIDFVTVGKYDASQPKGQEFSLN-RAIIWYDGTEKVPVSVCSESCPPGTRKAVKKGRPVCCYDCINCADGEINNET-DSLDCHKCQPDYWPNAEKIKCLPKPVEFLSWDEILGNTLAAFSIAGSLVALSMALVFYKNRVSPIVRANNSELSFLLLFSLTLCFLCSLTFIGQPTEWSCMLRHTAFGITFVLCISCVLGKTIVVLMAFKATLP-GSNVMKWFGPPQQRLSVFGFTLVQIIICVLWLTISPPFPYKNMQHYKDKIILECSLGSAVGFWAVLGYIGLLAFLCFVLAFLARKLPDNFNEAKFITFSMLIFCAVWITFVPAYVSSPGKFTVAVEIFAILASSFSLILLIFAPKCFVIVFRPEENTKRHLLGKVPPKAL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M3AV03-1", "uniprot_id": "A0A8M3AV03_DANRE", "id": "A0A8M3AV03-1", "name": "", "aln": "--------------MYNNVLLIVTLQCIITRLYVVYGNRLGSCILQGDPQPPVLFDEGDFIIGGAFSIHYYLRTEKHTYTMRPQSLECSGSMDFRELRFARVLQFAIQEINNSSDLLPGITLGYRIYDSCGSVPMAVKLSFQLANGLDLIFNDNDSCSKSAAVAALVGESGSTPSISISRLYGPFGIPQVSHYATCACLSDKRQHPTFFRTIPSDHHQAAALARMVKRFGWTWIGAVRSDSDYGNNGMASFLKAAEEEGICVEYSEAYYR--TQPRSKLMRVADVIRRSTARVIVAFMASGDMRLLLEELSQQPLPPMQWIGSEAWFTDPEMLR---FNMCIGGVGFAIPRSVIPGFRTFLLDLSPQRAMKFPLLTEFWESSFSCSLKQQTGPSTGMPACDGTEDLGRLKNPYTDTSQLRISNMVYKATYAIAHALHGIIC--------NEKKCNKNIKIEPREVLDKLKQVKFSKNN-YSVSFDAYGDPVAVYELVNWQLQKDGSIDFVTVGKYDSSQPKGKEFSLS-RAIIWYDGTEEVPVSVCSESCPPGTRKAVQKGRPVCCYDCINCADGEISNDT-DCLDCHECLSDYWPNNEKNKCLRKPVEFLSWDEILGIILAAFSVAGSLVALSMALVFYKNRASPIVRANNSELSFLLLFSLTLCFLCSLTFIGQPTEWSCMLRHTAFGITFVLCISCVLGKTIVVLMAFKATLP-GSNVMKWFGPSQQRLSVFGFTLVQIIICVLWLTISPPFPYKNMQHYKDKIILECSLGSAVGFWAVLGYIGLLAFLCFVLAFLARKLPDNFNEAKFITFSMLIFCAVWITFVPAYVSSPGKFTVAVEIFAILASSFGLILCIFAPKFFIIIFRPERNTKKHIMGKVPSKAL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1Q1C5-1", "uniprot_id": "A0A8M1Q1C5_DANRE", "id": "A0A8M1Q1C5-1", "name": "", "aln": "--------------MNAHLLFTVKMLCIARLCIAVCGVDLGTCILQGDAQPPALSEDGDFIVGGAFTIHYYVRTEKYTYTRRPQPLECSGSMDFRELRFARALQFAIQEINNSSDLLPGIFLGYHIYDSCGSVPMAIKVALQLANGLDPKYNDTDSCAKSAAVLALVGDSASTPAISISRIFGPFEIPQVSHYATCACLSDKRQHPTFFRTIPSDHHQAAALARMVKRFGWTWIGAVRSDSDYGNNGMASFLKAAEKEGICVEYSEAYYR--TYPLSKLKRVADVIRRSTARVIVAFVAAGDMRFLLEELSKEPLPPMQWIGSEAWVSDPQMLR---FNLSIGTMGVAVPRSLIPGFRKFLLDLSPYKVLKFPLLTEFWESSFSCSLQQQTDPSTGMPACDGTEDLGRLKNPYTDTSQLRVSNMVYKATYAIAHALHGIVC--------NETQCSKNIKVKPRQVFDQLKQVNFSKNN-YSVSFDANGDPVAVYELVNWQLQGDGSIDFVTVGKYDASQPEGQEFSLN-KAIIWYDGSEKVPVSVCSENCPPGTRKAVKKGRPVCCYDCIPCGEGEISNKT-DSPDCDKCPPDYWPSTEKDKCLPKPVEFLSWDEILGIILAVLSVSGSLLALSMALVFYKNRASPIVRANNSELSFLLLFSLTLCFLCSLTFIGQPTEWSCMLRHTAFGITFVLCISCVLGKTIVVLMAFKATLP-GSNVMKWFGPPQQRLSVFGFTLVQIIICVLWLTISPPFPYKNMQHYKDKIILECSLGSAVGFWVVLGYIGLLASLCFVLAFLARKLPDNFNEAKFITFSMLIFSAVWITFIPAYVSSPGKFTVAVEIFAILASSFSLILCIFAPKFFIILFRPEENTKKHLMGKVQSKSY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q1LV89-1", "uniprot_id": "Q1LV89_DANRE", "id": "Q1LV89-1", "name": "", "aln": "-----------------MCITLNICLHLSFIFISVN---SDSCQIQGHFKLNRMYKDGDYIIGGLFEVQHLKVFPELSFRMEPEQPKCE-EFYMSSFQQAQTMVFAIDEINKNPNLLPNITLGYHLYDNCLKLVVAFRAATTLISGTEETFSNFN-CTGPPPVIAIVGDPGSTHSIAVSSVLGLFHVPLISYYATCSCLSNRKKYPSFFRTIPSDAFQVRAMVQILKYFGWTWVGVLYSDDDYGIYAAQSFQQEMQRFKGCVAFSEIVPY--DNHR-DIQRIVAVIKASTARVVVAFST--DLLPLMEELLQQNVTGRQWIASEAWSTSPVLHLPRFVPLVRGTLGIAIHRGKIKGLHEFLLHIQPDNDPTNNMVRIFWENMFGCSFEKGNG--YGEKMCTAQEDLNITVNEYNDVSELRASYNVYKAVYALAHALHDLMQCEEGRGPFSGNSCADITKLKPWQMVPYLQKVNFTTGFGDHVSFDENGDALAIYDVMNWHPSSDGLIVVRTVGVVDEGASAGRVLTLDEDAIYWNFETKKPPRSVCSESCPPGTRRAMRKGLPVCCFDCLPCADGEISNMS-DATECTSCPNEFWSSPKKDQCVPKEVEFLSYEDPLGISLTTASLLGTCFCALVLAVFAHHHNTPVVRANNSELSFLLLLSLKLCFLCVLLFIGRPQLWTCQLRHAMFGISFVLCVSSILVKTMVVIAVFKSSRPEGKSAVKWFGAVQQRGTVLVLTAVQIVICVVWLSTASPTPHKNILYVRSKIVFECSIGSMAGFAILLGYIGILAAVSFLLAFLARNLPDNFNEAKFITFSMLIFSAVWIAFIPAYVSSPGKYSVAVEIFAILASSFGLLVAIFVPKCYIIILHPERNTKKAIMGRTAEK--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0ABK0LAY5-1", "uniprot_id": "A0ABK0LAY5_RAT", "id": "A0ABK0LAY5-1", "name": "G-protein coupled receptors family 3 profile domain-containing protein", "aln": "--------------MKKLCAFTIAIFSLKFCLILCS--LTEPNCFWRIKSSE--DNDGDLRSDCGFVLFTHEGPIPEDFYN----DIINFRIPARKYEFFLVLLFATDEINKNPYLLPNMSLIFNIIFGLCEDTLGVLDKAYLHQNSNSELFNYYCGINQLCDVDLTGPSWTTSLKLSIYSR----TPKIFFGSFNPNLSDHDQFPYIYQIAAKDTYLFHGMVSLMFHFGWTWIGLVISDDDQGIQFLSDLREEMQRHAICLAFVNMIPETMQIYKTRVKIYDQQLMTSSAKVVIIYGEVNSTLELSFRRWAYLGAQRIWITTSQWDVITHKKD-FSLDFSHGTVTFAHHHNDIAVFRNFMQTINTSMYPVDISQSMLQWNHFNCSISKNKK---KMDCFTFKNPLEWLIQHTFDMVLSEEGYNLYNAVYAVAHTYHKLIFQQVE---SQKMEEPKGLFTDCQQVTSLLKTIEFTNPVGELVDTKHKENQCATYDIFITWNFPQGLGLKVKIGSYFPCLPQSQQLHIS-EDWEWVTGETLIPPSVCSMTCTAGFRKIHQKETADCCFDCVQCQENEIANDTADMEQCVKCPDDSYANLEQSQCLQRVVTFLAYEDPLGMALGCMALSFSAITILVLVTFVKYKDTPIVKANNRILSYILLISLVFCFLCSLLYIGHPNQATCILQQTTFAIFFTVAISTVLAKTITVVTAFKLTTP-ERRIKKIMIKGAINLLIPICTLIQLVLCAVWLVISPPFIDRDIQSEHGKVIIICNKGSVIAFHFVLGYLGSLALGSFTVAFLARNLPDRFNEAKFLTFSMLVFYSVWITFLPVYHSTRGKDMVIVEVFSILASSAGLLGCIFFQKCYVLLVRPDLNVLRK----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6GL30-1", "uniprot_id": "A0A8I6GL30_RAT", "id": "A0A8I6GL30-1", "name": "", "aln": "--------------MKKLCAFTIAFFPLKFCLILCS--LTEPNCFWRIKKIE--VYDGDLQNDCGFVLFTLESPIEENFYN----HIINFRIPARKYEFFLVMFFATDEINKNPYLLSNMSLIFSFIFGMCEDTMGVLDKAYLHQNNYFDLLNYNCGRKKRCDVKLTGPSWKTSLKLSVNSR----APKIFFGPFNPNLSDHDQFPYIYQIATKDTYLLHGMVSLMFHFEWTWIGLVITDDDQGIQFHSDLREEMQRHAICLAFVIMIPESIKLYNTKFKIYDQQLMTSSAKVTIIYGKMISTLGLSFRRWAYLVARRIWITTSKLDDITYDKD-FSLDFFHGTVIFVHHHNDIATFRNFMQTINTSKYPVDISQSMGQWNHFNCSISKNKK---KMDFFMLKNPLEWLKQHTFDMVLSEEGYNLYNAVYAVAHTYHELIFQQVE---SQEMAKPKGLFTDCQKVASLLKTRVFTNPVGELVNMNHKENQCAKYDIFIIWNFPKGLGLKVKIGSYFPCLQQSQHLHIS-EDWEWVTGETLVPSSVCSETCTAGFRKSHQKQTADCCFDCVQCQENEIANDT-DMEQCVRCPDDSYANLEQTECLQRVVTFLAYEDPLGMALGCMALSFSAITILVLVTFVKYRDTPIVKANNRILSYILLISLVFCFLCSLLFIGHPNQATCILQQATFAIFFTVAISTVLAKTITVVTAFKLTTP-GRRIRKMMIKGATNLLIPICTLIQLVLCAIWLVTSPPFIDRDIQSEHGKVIIICNKGSVTAFHFVLGYLGSLALGSFTVAFLARNLPDRFNEAKFLTFSMLVFYSVWITFLPVYHSTRGKVMVIVEVFSILASSAGLLGCIFVQKCYVLLVRPDLNVLQK----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3ZQ04-1", "uniprot_id": "D3ZQ04_RAT", "id": "D3ZQ04-1", "name": "", "aln": "--------------MKKLCAFTVAFLFLKFSVILCRTQLTEPNCFWRIKNSE--DNDGDLQNDCGFILFTFKGRIEENFYNK-LLNFINFRIPARKYEFFLVMFFATDEINKNPYLLSNMSLLFSIIFGMCEDTLGIVDEVYSQSNKGLAFTNFICGVESTCDIQLTGPFWTTSLKLAIYSK----APKLFFGPFNPNLNDHVQFPYVHQVASKDTCLSHGMASLMLHFKWTWIGLAISDDDQGIQFLSDLKEEMQRHGICLAFVNMIPENMQIYMTMAKIYDKQIMTSSAKVVVIYGKINSTLEVSFRRWGNLGAHRIWITTSQWDVITNIKD-FNLDFFHGTVTFAHHHSDIAEFRNFMQTINTSKYPVDISQSMLGWNHFNCSISKNNS---KIDYFTFNNPLEWLAQHTFDMVLSEEGYNLYNAVYAVAHTYHELILQQVE---SQKMEEPKGVFTDCQQVASLLKTRVFTNPLGELVNMNHRENQCIEHDIFIIWNFPQGLGLKVKIGTYFPYFTHNQQLHIS-EDLEWATGGTLVPSSMCSMTCTAGFRKIHQKETADCCFDCVQCPENEVSNDTADMEQCVRCPDDSYTNLEQTQCLQRTVSFLAYEDPLGMALGCMALSFSAITILVLVTFVKYKDTPIVKANNRILSYILLISLVFCFLCSLLFIGHPNQDTCILQQTTFGVFFTVAISTVLAKTITVVTAFKLTTP-GRMIRRRMIKVATNFLIPICTLIQLALCGIWLGTSPPFIDRDIQSEHGKVIIICNKGSIIAFYFVLGYLGSLALGSFTVAFLARNLPDRFNEAKFLTFSMLVFYSVWITFLPVYHSTRGKVMIVVEVFSILASSAGLLGCIFVPKCYVLLVRPDLNVLQKKDELLYQ---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "K7N621-1", "uniprot_id": "K7N621_MOUSE", "id": "K7N621-1", "name": "", "aln": "--------------MKNLCVFTLSFFLLEFSLILCH--LTEPICFWRINNNE--DNDGDLRSDCGFFLAAVEGPTDDSYN------ISDLRIPARRYEFFLVMFFATDEINKNPYLLPNMSLIFPINHGQCEKTLGDLDKIYSEKNYTVEFTDYICVSFGTCFIALIGPSWKTSIKLSINSG----TPRVFFGPFNPKLSDHDQFPYVHQVATKDTRLSHAMVSLMFHFTWIWIGMVISDDDQSIQFLSDMREEMQRHGICLAFVNMIPEDMQLYMTRATIYDKQIMESTAKVVMIYGEMNSTLEVSFRRWEDLSIRRIWITTSQWDVITNKND-FSLDFFQGTVTFAHHVGEIANFRNFLQTMNSEKYTVNISESRLGWNYFNCSISKNSN---KKDHFTFNNTLEWTTLHKYDMVLSEEGYNLYNAVYAVAHTYHELVLQQVE---SQQMTVPKGTFTDCQQVSSMLKSRIFTNPVGELVNMKHRENQCTEYDIFIIWNFPQGLGLKVKIGSYLPCFQQSQQLHIS-EDLEWATGGSSVPPSLCSVTCTAGFRKIHQKQTADCCFDCDQCPENAVSNETVDMEQCMRCPDDKYANLEKTHCLQRAVSFLAYEDPLGMALGCTALSFSALTVLVLVTFVKYKDTPIVKANNRILSYILLISLVFCFLCSLLFIGHPNQATCILQQTTFGVFFTVAISTVLAKTITVLMAFKLTTP-GRRMRGMLASGAPNIVIPICTLIQLVLCGIWLVTSPPFIDRDMQSEHGKTIIICNKGSVIAFHFVLGYLGALALGSFTVAFLARNLPDRFNEAKFLTFSMLVFCSVWITFLPVYHSTQGTVMVVVEVFSILASSAGLLGCIFLPKCCVLLRIQNSNFLHKYKHELHS---", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : . * : : . . : ** :***. **. : : : . : * .: * : . *..: .. ..: ..* .:. :: : * *:* : .* . : . . *: : : .:::* : : . : : . . * : .. : :: . * . . . * * . * *.**:**: * :. :: :: *: : . :::. .* :* : : :. * * *:*: .* .* *: :* . **.** * :. : * : * :* * : :.. .: .*: : : **:: : :* * :. . : * : :*:*:*** **::**:** :**** : :**:* :* *::: *.: * :.:* :* **: *: .*: : * : . : * :* :* :** :.* : . : :: *. ** .* *** * *: .* :**:**.***.******:****::* :**::*:* * *: *. : *::*:** ** .*: ** * ::: : * ", "identical_positions": 136, "similar_positions": 188, "identity": "15.33%" }, { "cls_id": "homologset.agr.MGI:1316731", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88452-1", "uniprot_id": "STC2_MOUSE", "id": "O88452-1", "name": "Stanniocalcin-2", "aln": "-------------------MCAERLGQFVTLALVFATLDPAQGTDSTNPPEGPQDRSS-QQKGRLSLQNTAEIQHCLVNAGDVGCGVFECFENNSCEIQGLHGICMTFLHNAGKFDAQGKSFIKDALRCKAHALRHKFGCISRKCPAIREMVFQLQRECYLKHDLCSAAQENVGVIVEMIHFKDLLLHEPYVDLVNLLLTCGEDVKEAVTRSVQAQCEQSWGGLCSILSFCTSNIQRPPTAAPEHQPLADRAQLSRPHHRDTDHHLT------ANRGAKGERGSKSHPNAHARGRTGGQSAQGPSGSSEWEDEQSEYSDIRR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9R0K8-1", "uniprot_id": "STC2_RAT", "id": "Q9R0K8-1", "name": "Stanniocalcin-2", "aln": "-------------------MCAERLGQFVTLALVFATLDPARGTDSTNPPEGPQDRGS-QQKGRLSLQNTAEIQHCLVNAGDVGCGVFECFENNSCEIQGLHGICMTFLHNAGKFDAQGKSFIKDALRCKAHALRHKFGCISRKCPAIREMVYQLQRECYLKHDLCSAAQENVVVIVEMIHFKDLLLHEPYVDLVNLLLTCGEDVREAVTRSVQAQCEQSWGGLCSILSFCTSNIQRPPTAAPEHQPLADRAQLSRPYHRDTDHHLT------ANRGAKGERGSKSHLHAHARGGAGGQSAQGPSGSSEWEDEQSEYSDIRR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O76061-1", "uniprot_id": "STC2_HUMAN", "id": "O76061-1", "name": "Stanniocalcin-2", "aln": "-------------------MCAERLGQFMTLALVLATFDPARGTDATNPPEGPQDRSS-QQKGRLSLQNTAEIQHCLVNAGDVGCGVFECFENNSCEIRGLHGICMTFLHNAGKFDAQGKSFIKDALKCKAHALRHRFGCISRKCPAIREMVSQLQRECYLKHDLCAAAQENTRVIVEMIHFKDLLLHEPYVDLVNLLLTCGEEVKEAITHSVQVQCEQNWGSLCSILSFCTSAIQKPPTAPPERQPQVDRTKLSRAHHGEAGHHLPEPSSRETGRGAKGERGSKSHPNAHARGRVGGLGAQGPSGSSEWEDEQSEYSDIRR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB40E9D1-1", "uniprot_id": "A0AB40E9D1_DANRE", "id": "A0AB40E9D1-1", "name": "Stanniocalcin", "aln": "MLQWSGSPRQRYIQQRSSPSRDMRAQLTLGVFILFLAVRQTHTTESASAHDTSQEKSLNIHKKRLSLQNTAEIQQCLVNAGDVGCGMFECFNNNSCEIRGLHDICMTFLHNAGKFDSQGKSFIKDTLKCMAHGLRHKFSCVSRKCVAVKEMVFQLQRECYLKHNLCLAVRENVNVMVEMIHFKDLFPKGPHVELVNILLGCGEEVRVAIGRRIRTQCEQNWGALCGTLSLCALGKVEN-QASSTLAPVPDVTTTPGANT-NALHPTS-----FPHPEADGQAVWTLTETREEENLSSG--PQDNSSDAQKELKRSPNATKRR", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : : ::: :. :: *:::.. : .*::. :* ***********:***********:****:******:***.*************:********:*:* **.***:*.*:**** *::*** **********:** *.:**. *:*********: : *:*:***:** ***:*: *: : ::.****.**.**. **:*: . *.. * * : . . :: * . . *.*: . . .. .* .*. *..:: * ::* : **", "identical_positions": 138, "similar_positions": 82, "identity": "42.86%" }, { "cls_id": "homologset.agr.MGI:1316732", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K072-1", "uniprot_id": "A0A0G2K072_RAT", "id": "A0A0G2K072-1", "name": "", "aln": "MVPVLKVLLFLTLHLLQDTKSFKVHLNNNGYEGVVIAINPSVPEDERLIPSLKEMVTQASTYLFEASQGRFYFRNVSILVPMTWKSKSEYLMPKRESYDKADVIVANSHLKYGDNPYTLQYGQCGDRGRYIHFTPNFLLTDN-VRNYGPRGRVFVHEWAHLRWGVFDEYNEDRPFYISGKNTIEVTRCSTDIKGSKAVHERQRGSDVTRLCRWDSRTGLYEPKCKFFPDKIQTARASIMFMQNLNSVVEFCTEKTHNTEAPNLQNKICNGRSTWDVIKESADFQQAPPMRG--TEAPPPPTFSLLKSRQRVICLVLDKSGSMDTEDRLIRMNQAAELYLTQIVEKESMVGLVTFDSTAQIQNYLIKITNTGDYKKITGNLPQQAVGGTSICRGLEAGFQAITSSDQSTSGSEIVLLTDGED-DLISSCFEVVKHSGAVIHTIALGPKAARELETLSDMTGGLRFYANKDVNS--LMDAFSGISSASGNLSQQALQLESKAFNIGGGTWINGTVPVDSTIGNDTFFVITWTVQKPEIILRDPKRKKYTTSDFQDNKLNIRSARLQIPGTAETGTWTYSLFNKGVKPQLLTVTVTTRARSPTTQPLMATAHMSQSTAQYPSPMIVYARVSQGFLPVLGANVTAVIESENGSRVTLELWDNGAGADTVKNDGIYTRYFTDYHGNGRYSLKVRVQARKSKARLSLRQKNKSLYIPGYVENGKIILNPPRPEVPEEATEAAVEDFSRLTSGESFTVSGAPPDGGHAHVFPPSKVTDLEAEFKGDHIHLTWTAPGKVLDKGRAHRYVIRMSRHPPGLQD-FNDATLVNTSGLIPKEAGSEETFKFKPASFKIENGTQIYIAILANNEAGLTSKVSNIAQAVNFIPPEHSFSTLSPDISAICLTIWGLTVILNDILN--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QX15-1", "uniprot_id": "CA3A1_MOUSE", "id": "Q9QX15-1", "name": "Calcium-activated chloride channel regulator 3A-1", "aln": "MVPGLQVLLFLTLHLLQNTESSMVHLNSNGYEGVVIAINPSVPEDERLIPSIKEMVTQASTYLFEASQGRVYFRNISILVPMTWKSKPEYLMPKRESYDKADVIVADPHLQHGDDPYTLQYGQCGDRGQYIHFTPNFLLTDN-LRIYGPRGRVFVHEWAHLRWGVFDEYNVDQPFYMSRKNTIEATRCSTRITGTNVVHNCERGNCVTRACRRDSKTRLYEPKCTFIPDKIQTAGASIMFMQNLNSVVEFCTEKNHNAEAPNLQNKMCNRRSTWDVIKTSADFQNAPPMRG--TEAPPPPTFSLLKSRRRVVCLVLDKSGSMDKEDRLIRMNQAAELYLTQIVEKESMVGLVTFDSAAHIQNYLIKITSSSDYQKITANLPQQASGGTSICHGLQAGFQAITSSDQSTSGSEIVLLTDGED-NGIRSCFEAVSRSGAIIHTIALGPSAARELETLSDMTGGLRFYANKDLNS--LIDAFSRISSTSGSVSQQALQLESKAFDVRAGAWINGTVPLDSTVGNDTFFVITWMVKKPEIILQDPKGKKYTTSDFQDDKLNIRSARLQIPGTAETGTWTYSIT--GTKSQLITMTVTTRARSPTMEPLLATAHMSQSTAQYPSRMIVYARVSQGFLPVLGANVTALIEAEHGHQVTLELWDNGAGADTVKNDGIYTRYFTDYHGNGRYSLKVRVQAQRNKTRLSLRQKNKSLYIPGYVENGKIVLNPPRPDVQEEAIEATVEDFNRVTSGGSFTVSGAPPDGDHARVFPPSKVTDLEAEFIGDYIHLTWTAPGKVLDNGRAHRYIIRMSQHPLDLQEDFNNATLVNASSLIPKEAGSKETFKFKPETFKIANGIQLYIAIQADNEASLTSEVSNIAQAVKLTSLEDSISALGDDISAISMTIWGLTVIFNSILN--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M3APN3-1", "uniprot_id": "A0A8M3APN3_DANRE", "id": "A0A8M3APN3-1", "name": "", "aln": "---MHLRSVFVLLWMLRLSTSTGIKLDGNGYIDITIAISSKVPEDDKLIDKIKDMVTEGSVHLYKALDKKVYFKEVTILVPLNWNSKG-FTKARTELFETGMIRIDNPHPAYGDEPYTNQYGECGAEGQYIHFTPNFLRDDKLIRLYGSRGKVLVHEWAHLRWGVYDEYSEKTPFYRSASGKIEATRCSKNIEG----QLYDVTADPLQPCQNDPQTSLPTDGCRFIPNKYQSTDSSMMSLPSLDSVITFCRESEHNYEAPNLQNAKCSNKATWTVIFEDSVDKDALRSLKPMASTPPAPNFKVVQRMQRTVCLVLDVSGSMK-GSRILRLQQASAHFLQNIIEDQSSVALVTFSTDASTLSALTTIDKESTRENLVKLLPNVAEGATNMCKGLNLGLQVLKTDNQDVLGDEIIFLTDGEATDTLSNCVPAAINSGAIIHTIALGDKADKALREMADKTGGKFITASDDVLSNQLLNGFSSLIMPTGNQTKDPVQIDS--VGIKTSDWFNGTVSVDQTIGTKTSFTITYETKLPRISIQSPSGLTYSQTQMRHDEP-AKTVTLKVPGTAQTGDWKYSILS--PTLQSLTVTATSQAARANVPPITVKAQMNQQFSDGSKPMIVFAEVVQNYKPLIKAEVWATLESESGTVHELQLLDNGAGADTFKDDGVYSRYFTRMK-KGRSSLKVRVKNKDGQARFTLQKRGGAPYVPGYVVNGVVELNPPKLSVSEELPEVG--SFTRTATGESFEVS---LTSSKPPKFPPCKIIDLSAEIQEDAVLLSWTAPGEDLDEGSAKSYDIRWSFEVKDLLFNFSNAHVVNTSVISPQVFGSVEQHLFN-LSFPIQNGTILFFAIQSEDNEKLKSEMSNVASGLQIIPNPN-TGDLDLKLIFIAISVCLASVVVIGIFGITTWALTRKKLSDS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*: * :*: : * ::*:.*** .:.***...****::** .:*:***:.*.:*::* : :.**::::****:.*:** : .: * ::.. : : :.* :**:*** ***:** .*:********* *: :* **.**:*:***********:***. . *** * ...**.****. * * : : : *: *.:* * * *:*:* *:: :*:* : .*:**: ** *. ** ******* *. ::** ** .: ::* :.:**.*.*.::: :*.:***** ****. .*::*::**: :* :*:*.:* *.****.: * . * .* . . :::. **: * *.*.:*:**: *:*.:.:.:*.. *.**::***** : : .*. .. .***:******* .* : *. ::* *** : *..*: * *::.** : .:*. :::.:*::* ..: . *:****.:*.*:*..* *.**: .: *.* ::.*. .*: ::::.:: ::. *::****:** *.**: . * :*:*.*::* .. *: ..*:*.*. :: .. ***:*.* *.: *:: *:* * :*:* * *:* ********.*:**:*:**** : :** ******: : .::*::*:::. : *:**** ** : ****: .* ** *. .*.* ::* ** ** ..:. ***.*: **.**: * : *:*****: **:* *: * ** * . .* *.:* :**:* : *: ** * . *: :* * ** :::** :::: *.*::**:*..::: . . . *. .: *.::: :*:. .*:. ", "identical_positions": 342, "similar_positions": 321, "identity": "37.01%" }, { "cls_id": "homologset.agr.MGI:1316735", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8N7TDV0-1", "uniprot_id": "A0A8N7TDV0_DANRE", "id": "A0A8N7TDV0-1", "name": "", "aln": "MRISLGWVVCLVKEMHVNLLLILTLLCIRRLFPAVCGVHLGTCILQGDPQPPSLFSKGDFVIGGTFTIHYYLRTEKRTYTVRPQPLMCSGSMDFRELRFARVLQFAIQEINNSSNLLPGITLGYHIYD-SCASVPMVIKVAVQLANGLQLAFNDTDSCAQSSEVLALVGESGSTAAITTSRLFG---PFGIPQVSHYATCACLSDKRQHPTFFRTIPSDHHQAAALARMVKRFGWTWIGAVRSDSDYGNNGMASFLKAAEVEGICVEYSEAYYRTQTRNKLQRVADVIRRSTARVIVAFMAAGDMRFLLEELSQQPPPPMQWIGSEA-WVTDPQMLR---FNLSIGAVGFAIPRSVIPGFRKFLLDLSSEQALKIPVLKEFWESSFGCSLKQHTGYFSGMPACDGTEDLGTLKNPYTDTSQLRISNMVYKATYAIAHALHGIVC--------NGKLCDKNIKVEPRKVSDQLKQVNFSKNN-YSVSFDANGDPVAVYELVNWQLQGDGSIDFVTVGKYDASQPKGQEFSLN-RAIIWYDGTE-KVPVSVCSESCPPGTRKAVKKGRPVCCYDCINCADGEINNET-DSLDCHKCQPDYWPNAEKIKCLPKPVEFLSWDEILGNTLAAFSIAGSLVALSMALVFYKNRVSPIVRANNSELSFLLLFSLTLCFLCSLTFIGQPTEWSCMLRHTAFGITFVLCISCVLGKTIVVLMAFKATLP-GSNVMKWFGPPQQRLSVFGFTLVQIIICVLWLTISPPFPYKNMQHYKDKIILECSLGSAVGFWAVLGYIGLLAFLCFVLAFLARKLPDNFNEAKFITFSMLIFCAVWITFVPAYVSSPGKFTVAVEIFAILASSFSLILLIFAPKCFVIVFRPEENTKRHLLGKVPPKAL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M3AV03-1", "uniprot_id": "A0A8M3AV03_DANRE", "id": "A0A8M3AV03-1", "name": "", "aln": "--------------MYNNVLLIVTLQCIITRLYVVYGNRLGSCILQGDPQPPVLFDEGDFIIGGAFSIHYYLRTEKHTYTMRPQSLECSGSMDFRELRFARVLQFAIQEINNSSDLLPGITLGYRIYD-SCGSVPMAVKLSFQLANGLDLIFNDNDSCSKSAAVAALVGESGSTPSISISRLYG---PFGIPQVSHYATCACLSDKRQHPTFFRTIPSDHHQAAALARMVKRFGWTWIGAVRSDSDYGNNGMASFLKAAEEEGICVEYSEAYYRTQPRSKLMRVADVIRRSTARVIVAFMASGDMRLLLEELSQQPLPPMQWIGSEA-WFTDPEMLR---FNMCIGGVGFAIPRSVIPGFRTFLLDLSPQRAMKFPLLTEFWESSFSCSLKQQTGPSTGMPACDGTEDLGRLKNPYTDTSQLRISNMVYKATYAIAHALHGIIC--------NEKKCNKNIKIEPREVLDKLKQVKFSKNN-YSVSFDAYGDPVAVYELVNWQLQKDGSIDFVTVGKYDSSQPKGKEFSLS-RAIIWYDGTE-EVPVSVCSESCPPGTRKAVQKGRPVCCYDCINCADGEISNDT-DCLDCHECLSDYWPNNEKNKCLRKPVEFLSWDEILGIILAAFSVAGSLVALSMALVFYKNRASPIVRANNSELSFLLLFSLTLCFLCSLTFIGQPTEWSCMLRHTAFGITFVLCISCVLGKTIVVLMAFKATLP-GSNVMKWFGPSQQRLSVFGFTLVQIIICVLWLTISPPFPYKNMQHYKDKIILECSLGSAVGFWAVLGYIGLLAFLCFVLAFLARKLPDNFNEAKFITFSMLIFCAVWITFVPAYVSSPGKFTVAVEIFAILASSFGLILCIFAPKFFIIIFRPERNTKKHIMGKVPSKAL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1Q1C5-1", "uniprot_id": "A0A8M1Q1C5_DANRE", "id": "A0A8M1Q1C5-1", "name": "", "aln": "--------------MNAHLLFTVKMLCIARLCIAVCGVDLGTCILQGDAQPPALSEDGDFIVGGAFTIHYYVRTEKYTYTRRPQPLECSGSMDFRELRFARALQFAIQEINNSSDLLPGIFLGYHIYD-SCGSVPMAIKVALQLANGLDPKYNDTDSCAKSAAVLALVGDSASTPAISISRIFG---PFEIPQVSHYATCACLSDKRQHPTFFRTIPSDHHQAAALARMVKRFGWTWIGAVRSDSDYGNNGMASFLKAAEKEGICVEYSEAYYRTYPLSKLKRVADVIRRSTARVIVAFVAAGDMRFLLEELSKEPLPPMQWIGSEA-WVSDPQMLR---FNLSIGTMGVAVPRSLIPGFRKFLLDLSPYKVLKFPLLTEFWESSFSCSLQQQTDPSTGMPACDGTEDLGRLKNPYTDTSQLRVSNMVYKATYAIAHALHGIVC--------NETQCSKNIKVKPRQVFDQLKQVNFSKNN-YSVSFDANGDPVAVYELVNWQLQGDGSIDFVTVGKYDASQPEGQEFSLN-KAIIWYDGSE-KVPVSVCSENCPPGTRKAVKKGRPVCCYDCIPCGEGEISNKT-DSPDCDKCPPDYWPSTEKDKCLPKPVEFLSWDEILGIILAVLSVSGSLLALSMALVFYKNRASPIVRANNSELSFLLLFSLTLCFLCSLTFIGQPTEWSCMLRHTAFGITFVLCISCVLGKTIVVLMAFKATLP-GSNVMKWFGPPQQRLSVFGFTLVQIIICVLWLTISPPFPYKNMQHYKDKIILECSLGSAVGFWVVLGYIGLLASLCFVLAFLARKLPDNFNEAKFITFSMLIFSAVWITFIPAYVSSPGKFTVAVEIFAILASSFSLILCIFAPKFFIILFRPEENTKKHLMGKVQSKSY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9PFV7-1", "uniprot_id": "A0A8M9PFV7_DANRE", "id": "A0A8M9PFV7-1", "name": "", "aln": "-----------------MLLYLCTLLLFFKLKVSVG---NASCKIMGEPKYPLLFKDGDVTIGALFPVHSIETAPSFEFTQKPQLLSCS-SVNLRDFRLAQILIFAIEEINRSESLLPKLSLGYKIYD-TCSSKLSSMSATMALMNSFEFAGRDK--CNGQTSVHAIIGETESSATVILTRTTG---PFKIPVISHAASCECLSSRKEYPSFFRTISSDYHQGRALAYIVKHLGWSWVGAVNSDNDYGNYGMAIFLNTAHKEGICVEYSEKFYRTEPE-KLKKVVDTIKKSTAKVIVAFISFLEMRLLVEQLSAENITGLQIVGVEG-WTTSKSLITPKTLNVLRGSLGFAMRKIYIEGFAEYVL-------------KPFWDTAFPC-IPNQRNDSWVILNCSRYQDLLVLKNYIEDVPEHRFSINVYNAVYAVAHALHSLFK------CKEQEGCEKDLLTQPQQVVDALKKVNFTVKMGDRVWFDSTGATLAQYEVVNWQQNSDGSVNFKKVGYYDASLPPDQRFVLNIKEILWAGGNL-KKPRSVCSESCPPGTRKAAQKGRPICCYDCIPCADGEISNDT-DSNNCKQCQGEYWSNADKNKCVQKSVEFLSFTEVMGIVLVFFSLFGAGLTVLVAILFYSKKDTPIVKANNSELSFLLLFSLTLCFLCSLTFIGQPTQWSCMLRHTAFGITFVLCISCVLGKTLLVLMAFKATLP-GSNIMKWFGPVQQRLSVLAFTFIQVLICVLWLSISPPFPHKNMKYYEEKIILECSLGSTIGFWAILGYIGLLAALCFILAFLARTLPDNFNEAKFITFSMLIFCAVWITFIPAYVSSPGKFTVAVEIFAILSSSISLLLCIFAPKCYIILLKPEQNTKQYMLGKTTSKFY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M3B2Z8-1", "uniprot_id": "A0A8M3B2Z8_DANRE", "id": "A0A8M3B2Z8-1", "name": "", "aln": "-----------------MLLFLYSVLSLYHLNTKAE---NTLCQMIGNPKYPLLSKDGDITIGALFVIHSEVSLPSFAFTQKPNLLSCS-SLNIKDFRLAQTMIFAIEEINKNTNLLPNISVGYQIYD-TCGSRFHSMSATMALMNGPKNSEGYT--CNEQSSVHAIVGETESSNTIILSRTTG---PFKIPVISPTATCECLSNRKEFPSFFRTIASDYHQSRALAYIVKHFGWTWVGAVNSDNDYGNNGMATFQKTAKEVQICVEYSVKFIRTETE-KIRNVVNVIKKGTAKVIVAFLTGFEMKSLLEQLSSQNITGLQMIGVEA-WITSKTLITSKSFHVLGGSLGFAVRKIQIEGFADYVM-------------KAFWDTAFQS-FSN------ADLNYSQYQDLLLVKNYNEDVLEQRFVSYVYKAVYALAHSLHSLLR------CTEQGGCGKALTIQPHQLVEALRKVNFTVKMGDQVWFDSTGGVIAQYDVVNWQQNSDGSVQFQSVGYYDASLSPDQRFMLNTEKIVWAGGQL-EKPRSVCSESCPPGTRKASQKGRPVCCHDCIPCADGEISNET-DSNNCKQCPGEYWSNANKNKCVTKAVEFLSFTEVMGIILVFFSLFGAGLTVLVAILFYSKKDTPIVKANNSELSFLLLFSLTLCFLCSIPFIGRPTQWSCMLRHTAFGITFVLCISCILGKTIVVLMAFKATLP-GSNIMKWFGPVQQRLSVLAFTLIQGLICVIWLTKSPPFPYKNMKYFQEQIILECSVGSTIGFWAVLGYIGLLAVLCFILAFLARTLPDNFNEAKFITFSMLIFCAVWITFIPAYVSSPGKLTVAVEIFAILASSFGLLFCIFAPKCYIILLQPEQNTKQQMMAKTPSKI-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9PPM0-1", "uniprot_id": "A0A8M9PPM0_DANRE", "id": "A0A8M9PPM0-1", "name": "", "aln": "-----------------MSVFFCTLLIFFQLYAKAE---KPICIMMGDPKYPLLSKEGDISIGAVFPVHSIETLPLFKFTQKPQLLSCS-SVSIRDFRMAQIMAFAIEEINRNESLLPNVSLGYQIYD-TCGSGLSLMGANMALMNVQEFASRGS--CNGQSPVHAIIGETESSNTVILSRTTG---PFKIPVISPSASCECLSNRKEYPYFFRTIASDYHQSRALAYIIKYFGWSWVGAVNSDNDYGNHGMAIFLSTAEKEGVCVEYSVKFQRTEPE-KLKKVVDTIKKGTSKVIVAFLTEFEMKNLLEYLIIQNVTGLQVIGVEA-WITANSMIKPNSFHVLGGSLGFAVKKLNIEGFEDYVT-------------KAFWETAFPCSQTSQKENSQYKLICNIYRDLLVLKNDNKDVPEQRYASNVYKAVYAVAHSLHNILK------CRENGACETDMKIQPQQVVEALRKVNFTIKMGDCVWFDSTGAVVAQYEVVNWQPDYNGSIQFKPVGYYDASLPPNQRFVINTENIIWAGGQL-KKPRSVCSENCPPGTRKAVQKGRPVCCYDCIPCAEGEISNET-DSNNCKQCPGEYWSNAEKNKCVLKAVEFLSFKELMGIVLVFFSLLGAGLTTLVAILFYSKKDTPIVKANNSELSFLLLFSLMLCFLCSLTFIGRPTEWSCMLRHTAFGITFVLCISCVLGKTIVVLMAFKATLP-GSDVMKWFGPIQQRLSVLVITIVQVLICVLWLAVSPPLPYKNTKYFKEKIILECSLGSTIGFSAALGYIGLLAILCFILAFLARTLPDKFNEAKFITFSMIIFCAVWITFIPSYLSSPGKLTVAVEIFAILASSFGLLFCIFLPKCYIIMCKPEQNTKLHIIGKLNK---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9PAH3-1", "uniprot_id": "A0A8M9PAH3_DANRE", "id": "A0A8M9PAH3-1", "name": "", "aln": "-------------MTKKSELLLLMVLVTHGICVPNL---AQVCRLLGQPALPLLSEERNINIGAIFSLHKSALLKSHNFTSKPKQTTCG-GLNLREFKFVQTLIFAIEEINN-SSLLPGASLGYKIYD-SCGSVAQAIFSGMALMNGYEETLSDTS-CSTPPAVHAIVGESNSSPTIGLASVVG---PFSLPLVSHFATCSCLSNRKRFRTFFRTIPSDYYQSRALAQLVKHFGWTWVGTVRSRSDYGNNGIATFEEAAKQEGICIEYSEAVFKTDPEVQFLKTIEVIKKATTKVVVAFMAFGDFVLLLKVMAQQNITGIQWIGSES-WITSRNLAETKEYHFLSGAVGFAIANSKPVGLREFLMNVHPDKELNNELLKEFWETVFLCSFRNS-----SSGGCTGSEKLSELQNEYTDFSELRIENKVYTAVYAVAHSLHNVLKG-----FKFFTNSSKKQLPTPQKVLEYLRDVNFTVNTNENIFFDASGDPVARYDLVNWQPTKDGSLQFKLVGIYDSSLPSEQRLQINQESMLWAGNSG-QLPVSVCSESCPPGTRKAVQKGRPICCYDCIPCAEGEISNYT-DSSDCFPCGLEYWSNESKDRCVLKVIEFLSYTEIMGVGLCIFSFIGVLLTATVSFLFYFYKETPIVRANNSELSFLLLFSLTLCFLCSLTFIGRPTDWSCMLRHTAFGITFVLCISCVLGKTIVVLMAFRATLP-GSNVMKWFGPLQQRLSVVSLTLIQVIICVLWLTMSPPFPFLNLSYYREKIILECNLGSAFGFWAVLGYTGLLSTLCFVLAFFARKLPDNFNEAKFITFSMLIFCAVWLTFIPAYVSAPGKYTVAVQLFAILASSFGLLFCIFAPKCYIILLKPEKNTKKQMMGKS-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0T300-1", "uniprot_id": "A0T300_DANRE", "id": "A0T300-1", "name": "", "aln": "--------------MANTLSLLLLLLLLHGHFLPAT---VQICDLVGQSALPVLSAERDINIGAIFSIHRNALLRLYPFTSKPEPTTCV-RLNLREFKFAQTFIFAIEEINNNTQLLPGVTLGYKIYD-ACNAISPTLVSGMALINGYENTLSDTS-CSQPPAVQAIVGESSSSPTTALAALVG---PFNIPVISHFATCACLSNRKRYPSFFRTIPSDYYQSRALAQLVKHFGWTWVGTVRSRSDYGNNGITAFEDAAKQEGICIEYSEAILRTDPQEQFRKTVEVIKKGTSKVVVAFISFGDFAPLVKVIAENNITGLQWVGSES-WITSRNLAETKEYSFLSGAVGFAIVNAKLVGLKEFLVNVHPDQEPKNKLLKEFWETAFQCSFSNS-----DSALCTGSEKLGELKNEYTDVSELRIEHKAYAAVYAVAHTLHNVFKD-----VKAPNNS-KRELPTPQKVLQYMRNLSFTIKTGENIFFDASGDPVARYDLVNWQTAEDGSLQFKHVGIYDSSLPSKQRLQVNQEIMLWAGKSG-LLPLSVCTESCLPGTRKAVQKGRPVCCYDCIPCAEGEISNST-DSSDCFSCDLEYWSNEKKDRCILKVVEFLSYAEIMGIILCIVSFIGLLLTVMVTCLFYLHKETPIVRANNSELSFLLLFSLSLCFLCSLTFIGRPTQWSCMLRHTAFGITFILCISCVLGKTIVVLMAFRATLP-GSNVMKWFGPLQQRLSVVSLTLVQVIVCLLWLTLSPPYPYMNLSYYREKIILECNLGSAFGFWAVLGYTGLLSTLCFVLAFLARKLPDNFNEAKFITFSMLIFCAVWLTFIPAYVSSPGKYTVAVEIFAILVSSFGLLFCIFAPKCYIILLKPEKNTKKQMMGKL-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q1LV89-1", "uniprot_id": "Q1LV89_DANRE", "id": "Q1LV89-1", "name": "", "aln": "-----------------MCITLNICLHLSFIFISVN---SDSCQIQGHFKLNRMYKDGDYIIGGLFEVQHLKVFPELSFRMEPEQPKCE-EFYMSSFQQAQTMVFAIDEINKNPNLLPNITLGYHLYD-NCLKLVVAFRAATTLISGTEETFSNFN-CTGPPPVIAIVGDPGSTHSIAVSSVLG---LFHVPLISYYATCSCLSNRKKYPSFFRTIPSDAFQVRAMVQILKYFGWTWVGVLYSDDDYGIYAAQSFQQEMQRFKGCVAFSEIVPYDNHR-DIQRIVAVIKASTARVVVAFST--DLLPLMEELLQQNVTGRQWIASEA-WSTSPVLHLPRFVPLVRGTLGIAIHRGKIKGLHEFLLHIQPDNDPTNNMVRIFWENMFGCSFEKGNG--YGEKMCTAQEDLNITVNEYNDVSELRASYNVYKAVYALAHALHDLMQCEEGRGPFSGNSCADITKLKPWQMVPYLQKVNFTTGFGDHVSFDENGDALAIYDVMNWHPSSDGLIVVRTVGVVDEGASAGRVLTLDEDAIYWNFETK-KPPRSVCSESCPPGTRRAMRKGLPVCCFDCLPCADGEISNMS-DATECTSCPNEFWSSPKKDQCVPKEVEFLSYEDPLGISLTTASLLGTCFCALVLAVFAHHHNTPVVRANNSELSFLLLLSLKLCFLCVLLFIGRPQLWTCQLRHAMFGISFVLCVSSILVKTMVVIAVFKSSRPEGKSAVKWFGAVQQRGTVLVLTAVQIVICVVWLSTASPTPHKNILYVRSKIVFECSIGSMAGFAILLGYIGILAAVSFLLAFLARNLPDNFNEAKFITFSMLIFSAVWIAFIPAYVSSPGKYSVAVEIFAILASSFGLLVAIFVPKCYIIILHPERNTKKAIMGRTAEK--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "D3ZXT3-1", "uniprot_id": "D3ZXT3_RAT", "id": "D3ZXT3-1", "name": "", "aln": "-------------------MKKLCAFTVSFLFLKFS---LILCSFTELSCFWRMKNSEDSDGDLRSDCGFVLLTTKKNIED-FYNDINEVRIPARRYEFFLVMFFATDEINNNPYLLPNISLIFSIIAGLCEDTLGVLDEIYSQQNNSWNIVNYICEKGQRCDIELTGPSWKASVKLSIHSMIPSVRMCDTGCVFFGPFNPNLSDHDQFPYMYQIATKDTCLSHGMVSLILHFRWNWLGLVISDDDQGIQFLSDLREEMQSHGICLAFVNMIPETMQVYMIKAKIYDKQIMTSSAKVVIIYGEMNSTLEVSFRRWSYLGVQRIWITTSQWDVITIKKDFNLDFFHGTLTFAHHKVEVAKFRNFMQTRNPAKYPVKFFESVLGWNYFNCSISKNSN---LMDHFIFNNTLEWIALNKYDMVLSEEGYNLYNAVYAVAHTYHELILQQTE---SQNIAEPNGVFIDCQQVASLLKTRVFTNPVGELVNMKHREKQCVEYDIFITWNFPEGLGLKVKIGSYFPCFPQSQQLHISEDLEWATGGTS--VPSSMCSATCTAGFRKIHQKQTADCCFDCVQCPENEVSNETADMEQCVRCPDDMYANLEQTQCLQRTVSFLAYDDPLGIALGCMALSFSAITILVLVTFVKYKDTPIVKANNRILSYILLISLVFCFLCSLLFIGHPNQATCILQQTTFGVFFTVAISTVLAKTITVVMAFKLTTP-GRRLRGMMITWASNFVIPFCTLIQLVLCGIWLVTSPPFIDRDIQSEHGKTIIICNKGSVIAFHVVLGYLGSLALGSFTIAFLARNLPDRFNEAKFLTFSMLVFYSVWITFLPVYHSTRGKVMVVVEVFSILASSADLLGCIFVQKCYIILVSSNSNFLHK----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A3Q4EIC8-1", "uniprot_id": "A0A3Q4EIC8_MOUSE", "id": "A0A3Q4EIC8-1", "name": "", "aln": "-------------------MKKLCAFTISLLFLKFS---LILCCWSEPSCFWRIKNSDDNDGDLQRECHFYLGAADTPVEDNFYSSLLKFRIAASEYEFLLVMFFAIDEINRNPYLLPNITLMFSFIGGNCQDLLRVMDQAYTQINGHMNFVNYFCYLDDSCAIGLTGPSWKTSLKLAMHSSMP--------LVFFGPFNPNLRDHDRLPHVHQVAPKDTHLSHGMVSLMFHFRWTWIGMVISDDDQGIQFLSDLREESQRHGICLAFVNMIPENMQIYMTRATIYDQQIMTSSAKVVIIYGEMNSTLEVSFRRWEELGARRIWITTSQWDVITNKKDFTLNLFHGTITFAHHRVEIPKLNKFMQTMNTAKYPVDISHTILEWNYFNCSISKNSI---RMHHITFNNTLEWTSLHNYDMAMSDEGYSLYNAVYAVAHTYHEYIFQQVE---SQKKAKPKRYFTACQQVSSLMKTRVFMNPVGELVNMKHRENQCTEYDIFIIWNFPQGLGLKVKIGSYLPCFPQRQKLHISDDLEWAKGGTSPQVPSSVCSVACTAGFRKIYQKETADCCFDCVQCPENEISNET-DMEQCVRCPDDKYANIEQTHCLSRAVSFLAYEDPLGMALGCMALSFSAITILVLVTFVKHNDTPIVKANNRILSYILLISLVFCFLCSLLFIGPPDQVTCILQQTTFGVFFTVSVSTVLAKTITVVMAFKLTTP-GRRMRGMMMTGAPKLVIPICTLIQLVLCGIWLVTSPPFIDRDIQSEHGKIVILCNKGSVIAFHVVLGYLGSLALGSFTLAFLARNLPDTFNEAKFLTFSMLVFCSVWITFLPVYHSTRGRVMVVVEVFSILASSAGLLMCIFVPKCYVILIRPDSNIIKKHKGKVLN---", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : . : . . . : ** :***. *** : : : * . . : . :: : . * .: . ..: ..* .:. :: : *.*:* : * .* * : . . *: : : *: . *.: * : : : . * : .* . : :: : . * . . . * * * *.**:**: * . :: :: * : :. . *::. :* :* . : : :. * *:*: * .* *: :* . **.**: * :.*:.* : * :* * : :.. .: :*: : :.**:: : :* * :. . : * . :*:*:*** **::**:** :**** : *** * :* *::: **: * :.:* :* **: *: .*: : * * : . . : * :* ::* :** :.* : . : :: *. ** .* *** * *: .* :**:**.*** ******:****::* :**::*:* * *: *: *.*::*:** ** .*: ** * ::*: .: * ", "identical_positions": 147, "similar_positions": 183, "identity": "16.5%" }, { "cls_id": "homologset.agr.MGI:1316736", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WVR8-1", "uniprot_id": "MEN1_RAT", "id": "Q9WVR8-1", "name": "Menin", "aln": "------------MGLK-AAQKTLFPLRSIDDVVRLFAAELGR-EEPDLVLLSLVLGFVEHFLAVNRVIPTNVPELTFQPSP---APDPPGG-------LTYFPVADLSIIAALYARFTAQIRGAVDLSLYPREGGVSSRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSFITGTKLDSSGVAFAVVGACQALGLRDVHLALSEDHAWVVFGSNGEQTAEVTWHGKGNEDRRGQTVNAGVAERSWLYLKGSYMRCDRKMEVAFMVCAINPSIDLHTDSLELLQLQQKLLWLLYDLGHLERYPMALGNLADLEELEPTPGRPDPLTLYHKGIASAKTYYQDEHIYPYMYLAGYHCRNRNVREALQAWADTATVIQDYNY-CREDEEIYKEFFEVANDVIPNLLKEAASLLEAGEERPGEQAQGTQGQGSALQDPECFAHLLRFYDGICKWEEGSPTPVLHVGWATFLVQSLGRFEGQVR---------------QKVHIVSREAEAAEAEEP---WGDEAREGRR-RGPRRESKPEEPPPPK------------------------KPALDKGPGSGQSAGSGP---------------------PRKTSGTVSGTARG-TEVSSAAQAPAPAASPPP-------------------------------------EGPVLTFQSEKMKGMKELLVATKINSSAIKLQLTAQSQVQMKKQ--------------KVSTPS-DYTLS-------------------------------FLKRQRKGL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88559-1", "uniprot_id": "MEN1_MOUSE", "id": "O88559-1", "name": "Menin", "aln": "------------MGLK-AAQKTLFPLRSIDDVVRLFAAELGR-EEPDLVLLSLVLGFVEHFLAVNRVIPTNVPELTFQPSP---APDPPGG-------LTYFPVADLSIIAALYARFTAQIRGAVDLSLYPREGGVSSRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSFITGTKLDSSGVAFAVVGACQALGLRDVHLALSEDHAWVVFGPNGEQTAEVTWHGKGNEDRRGQTVNAGVAERSWLYLKGSYMRCDRKMEVAFMVCAINPSIDLHTDSLELLQLQQKLLWLLYDLGHLERYPMALGNLADLEELEPTPGRPDPLTLYHKGIASAKTYYQDEHIYPYMYLAGYHCRNRNVREALQAWADTATVIQDYNY-CREDEEIYKEFFEVANDVIPNLLKEAASLLETGEERTGEQAQGTQGQGSALQDPECFAHLLRFYDGICKWEEGSPTPVLHVGWATFLVQSLGRFEGQVR---------------QKVHIVSREAEAAEAEEP---WGDEAREGRR-RGPRRESKPEEPPPPK------------------------KPALDKGPGSGQSAGSGP---------------------PRKTSGTVPGTTRGGQEVGNAAQAPAPAASPPP-------------------------------------EGPVLTFQSEKMKGMKELLVATKINSSAIKLQLTAQSQVQMKKQ--------------KVSTPS-DYTLS-------------------------------FLKRQRKGL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00255-2", "uniprot_id": "MEN1_HUMAN", "id": "O00255-2", "name": "Menin", "aln": "------------MGLK-AAQKTLFPLRSIDDVVRLFAAELGR-EEPDLVLLSLVLGFVEHFLAVNRVIPTNVPELTFQPSP---APDPPGG-------LTYFPVADLSIIAALYARFTAQIRGAVDLSLYPREGGVSSRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSFITGTKLDSSGVAFAVVGACQALGLRDVHLALSEDHAWVVFGPNGEQTAEVTWHGKGNEDRRGQTVNAGVAERSWLYLKGSYMRCDRKMEVAFMVCAINPSIDLHTDSLELLQLQQKLLWLLYDLGHLERYPMALGNLADLEELEPTPGRPDPLTLYHKGIASAKTYYRDEHIYPYMYLAGYHCRNRNVREALQAWADTATVIQDYNY-CREDEEIYKEFFEVANDVIPNLLKEAASLLEAGEERPGEQSQGTQSQGSALQDPECFAHLLRFYDGICKWEEGSPTPVLHVGWATFLVQSLGRFEGQVR---------------QKVRIVSREAEAAEAEEP---WGEEAREGRR-RGPRRESKPEEPPPPK------------------------KPALDKGLGTGQGAVSGP---------------------PRKPPGTVAGTARG-PEGGSTAQVPAPTASPPP-------------------------------------EGPVLTFQSEKMKGMKELLVATKINSSAIKLQLTAQSQVQMKKQ--------------KVSTPS-DYTLS-------------------------------FLKRQRKGL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VM47-1", "uniprot_id": "Q9VM47_DROME", "id": "Q9VM47-1", "name": "Menin", "aln": "MSTITRSASASPMALNGVIDASLFPLKSTADVINLFRRALTSGIEPDLTLLSIVVGYIELSLTTGEAAAQAAQAAAAAVAAGDISQATTGGNDIIMGNSVPFPVVTHELIAGLYKKFQTILS-VVEK---PKPHRQATREVIKKVSDVIWNSLIRSSYKDRAHLQNLYSYLSGNKLDCFGVALAVVAGCQLLGYKDVRLAISEDHAWVVFGQKRVETIEVTWHGKGSEDKRGQDIRPGIESGSWLYLGGLAVVCERGMEVAAICAALNISLTSNSDCVEVAELQQQLLWLLYDLGHLKRYPMALGTLGELEEIHRTHPSISCEQLYREAIESARTHYRNHHVYPYTYQGNYYNRLLKYRDAFAAWANAADVIRLYTYQCRDDEEIYKELLDIANELIPYVMKTES---------SGHSAR------SILRDSEVFANLLRFYDGICQWEEDSLTPILHIGWAKPLVNNITKFDYDIRSQVVIKLPEDLEAEQAKAELARAEQEAKEAKESKEAAGSEAMEGNNNRMATKEEKSKNSELPTTLADLTAACGEKILNPDFLLQGGGQPFADQKQQPSGGESDNPELHNNNNNSNSNNNNNNHNADKKEAAATTTNATTTSNGSGTSVQLPVSSEANNAGQAQSQVQINDQLGKPQHKEAKKEETSDDYDPFEIMLKRPVITLYSQKMKGLKDLLLAEKLNTHAISLQVTAQSVASRKVRGVEKHSATISATITAISSSSGDSVLSGVGGGGGSGSAVTGGASLASSSLGGDSIAASRPKRTRRE-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.*: . : :****:* **:.** * ****.***:*:*::* *:.... . . : :. : ..** . ***. .:**.** :* : : .*: *: ::**::*********** ** :*****:*.*:*:::*.***. ***:***..** ** :**:**:********** : :* ********.**:*** :..*: . ***** * : *:* **** : .*:* *: ::*.:*: :***:***********:*******.*.:***:. * . **::.* **:*:*::.*:*** * ..*: * : *:*: ***::* **: *.* **:*******::::**::** ::* : .*..:: * *:*.* **:*********:***.* **:**:***. **:.: :*: ::* *..:. * ** **:*. *.** **.. * . :*.*.::. *. :* *: .. . ..* ::...*...:: ..:.* *..: : . : **:*: *:****:*:**:* *:*: **.**:**** .. * : :*:.* * .** ** *: ", "identical_positions": 266, "similar_positions": 196, "identity": "33.97%" }, { "cls_id": "homologset.agr.MGI:1316737", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5M840-1", "uniprot_id": "G0S2_RAT", "id": "Q5M840-1", "name": "G0/G1 switch protein 2", "aln": "MESVQELIPLAKEMMTQKSRGKLVKLYVLGSVLAFFGVVLGLVETVCSPFTAASRLRDQEAAVAELRDACEQQSLHKQALIAEGKTQEATLCSRALSLRQHAS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61585-1", "uniprot_id": "G0S2_MOUSE", "id": "Q61585-1", "name": "G0/G1 switch protein 2", "aln": "MESVQELIPLAKEMMAQKPRGKLVKLYVLGSVLALFGVVLGLVETVCSPFTAASRLRDQEAAVVELREACEQQSLHKQALLAGGKAQEATLCSRALSLRQHAS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P27469-1", "uniprot_id": "G0S2_HUMAN", "id": "P27469-1", "name": "G0/G1 switch protein 2", "aln": "METVQELIPLAKEMMAQKRKGKMVKLYVLGSVLALFGVVLGLMETVCSPFTAARRLRDQEAAVAELQAALERQALQKQALQEKGKQQDTVLGGRALSNRQHAS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:************:** :**:***********:*******:********** *********.**: * *:*:*:**** ** *::.* .**** *****", "identical_positions": 78, "similar_positions": 15, "identity": "75.73%" }, { "cls_id": "homologset.agr.MGI:1316740", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WVL5-1", "uniprot_id": "MORC1_MOUSE", "id": "Q9WVL5-1", "name": "MORC family CW-type zinc finger protein 1", "aln": "-MDKYALLQRAKLHLDFIHANSTTHSFLFGALAELLDNARDAGAVRLDVFSVDNETLQGGFMLCFLDDGCGMSPDEASDVIYFGTSKKRLSTLKFIGQYGNGLKSGSMRIGKDCILFTKKEETMTCLFFSQTFCEKEGLTEVVVPIPSWLTRTRESITDDPQKFFTELSIIFKYSPFKTEAELMQQFDMIYGRCGTLLIIYNLKLLLSGEPELDVTTDKEDILMAEAPEEIPERRSFRAYTAVLYFEPRMKIFIQAKRVQTKHLCYSLYKPRKYQYTTSSFKGKFKTEVQKAEEAVKRAELLFKEVQAKVNQPDRIALSSTQDALQKALQDVDTKHKSLRQKQRALRKARTLSLFFGVNTEDQHQAGMFIYSNNRLIKMYEKVGPQLKMKSLLGAGIIGIVNIPLETMEPSHNKQEFLNVQEYNHLLKVMGQYLIQYCKDIGISNRNLTLFWDEFKYQHSKDTDSSLESLQWRRRQAMGIPFILQCDLCLKWRVLPSSSNYQEKGLPDLWICASNPNNLENSCNQIERLPSIPLGTVNRRPPSKDERERQLQESVQRYQDKLVEAQPQKSQLIVTSKIPEFKSSCLSSALKEKSKLGRIQPSGADLTQGSPSSVKLSFMQRSQKRSTEDTHSDVEFICMTKIPKKSVKKTVKYLQPGHAPALLENLKLED------------------------TAQVSSREIKKQQSESLVQAGKASTDVASS-RDPTVTMVWDQSSTKVSLKQEEEEEVPLIKPDKQELCDDTPVVKGNSSALHWKSLPGVQMEDLSPRSGHKIN-SVSGDCQLPASPMPSQSMSVEETARKLLSNLREILLYFVPEFQLSSEFECTSVEELITNPELERCPENINEKLKTCFNQIQNIYMAQYEKRLKRKMQSIVYEANRRGLLNQVFLGQCELKRKRTEEKLSDLRAKLALLLQKLQLGGPAGDPQQIDAYLEDLLKED--RLPTALHEKSPESA--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZKF3-1", "uniprot_id": "D3ZKF3_RAT", "id": "D3ZKF3-1", "name": "MORC family CW-type zinc finger protein 1", "aln": "-MDKYALLQRAKLHLDFIHANSTTHSFLFGALAELLDNARDAGAVRLDVFSVDNGTLQGGFMLCFLDDGCGMSPDEASDIIYFGTSKKRLSTLKFIGQYGNGLKSGSMRIGKDCILFTKKEETMTCLFFSQTFCEKEGLTEVVVPIPSWLTRTRESITDDTQKFSTELSIIYKYSPFKTEAELMQQFDMIYGRCGTLLIIYNLKLLLSGEPELDVTTDKEDILMAEALEEFPERRSFRAYTAVLYFEPRMRIFIQAKRVQTKHLCYSLYKPRKYQYTTSSFKGKFKTEVKKAEEAVKMAELLFKEVQAKVNQPDRIVLSSAKDVIQKALEDVEAKHKDLRQKQRALRKAKTLSLFFGVHTEDRSQAGMFIYSNNRLIKMYEKVGPQLKMKSLLGAGVIGIVNIPLEIMEPSHNKQEFLNVQEYNHLLKVMGQYLIQYCKDTGISNRNLTLFWNKFEDQHSKDTDSSLEALQWRRRQAMAIPFILQCDLCLKWRVLPSSSSYQGKGFPDIWICANNPNNLENSCNQVECLPSIPLGTMNRRPPAKDEREKQLQESVQRYRDRLVDTQPQKSQLIVTSKIPEFKTSCLSSAHKEKSRLGRIKPPEDDLTQGSPSSAELSFNQRSQKRSTEDADSDVEFVCVTKIPKKSAKKNLKCLQPSHSPAMLENLKLED------------------------TAQVSSREMKRRQSENLVQERKAFTQVEASSRDPTVTVVWDKSSTKVSPKQEKEE-VALAKTDKQELCDDAPIVKRNSSALNWKSLTGVQMEDLSPHSGHKVS-SVNSDCQLLSSLMPSRSTSVEETARKLLSKLREILLYFVPEFQLSSEFECTSVEELITNPELERCPESINEKLKTCFKQIQNIYMAQYEKRLKRKMQSIIYEANRRVTLNEVLLEQCELKRKRTEEKLSDLCAKLALLLQKLQLGGPVRDFQQIDTYLEDLLKED--HLSTTLNKRSLESGQVKGAEH-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q86VD1-1", "uniprot_id": "MORC1_HUMAN", "id": "Q86VD1-1", "name": "MORC family CW-type zinc finger protein 1", "aln": "MDDRYPALQRAQLRLDFIHANSTTHSFLFGALAELLDNARDAGAERLDVFSVDNEKLQGGFMLCFLDDGCGMSPEEASDIIYFGRSKKRLSTLKFIGQYGNGLKSGSMRIGKDFILFTKKEETMTCVFFSQTFCEEESLSEVVVPMPSWLIRTRESVTDDPQKFAMELSIIYKYSPFKTEAELMQQFDVIYGKCGTLLVIYNLKLLLNGEPELDVKTDKEDILMAGALEDFPARWSFRAYTSVLYFNPWMRIFIQAKRVKTKHLCYCLYRPRKYLYVTSSFKGAFKDEVKKAEEAVKIAESILKEAQIKVNQCDRTSLSSAKDVLQRALEDVEAKQKNLKEKQRELKTARTLSLFYGVNVENRSQAGMFIYSNNRLIKMHEKVGSQLKLKSLLGAGVVGIVNIPLEVMEPSHNKQEFLNVQEYNHLLKVMGQYLVQYCKDTGINNRNLTLFCNEFGYQNDIDVEKPLNSFQYQRRQAMGIPFIIQCDLCLKWRVLPSSTNYQEKEFFDIWICANNPNRLENSCHQVECLPSIPLGTMSTISPSKNEKEKQLRESVIKYQNRLAEQQPQ-PQFIPVDEI-TVTSTCLTSAHKENTKTQKIRLLGDDLKHESLSSFELSASRRGQKRNIEETDSDVEYISETKIMKKSMEEKMNSQQQRIPVALPENVKLAERSQRSQIANITTVWRAQPTEGCLKNAQAASWEMKRKQSLNFVEECKVLTEDENT-SDSDIILVSDKSNTDVSLKQEKKE-IPLLNQEKQELCNDVLAMKRSSSLPSWKSLLNVPMEDVNLSSGHIARVSVSGSCKVASSPASSQSTPVKETVRKLKSKLREILLYFFPEHQLPSELEEP-----ALSCELEQCPEQMNKKLKMCFNQIQNTYMVQYEKKIKRKLQSIIYDSNTRGIHNEISLGQCENKRKISEDKLKNLRIKLALLLQKLQLGGPEGDLEQTDTYLEALLKEDNLLFQNNLNKVTIDARHRLPLEKNEKTSEN", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:*. ****:*:****************************** ********* .******************:****:**** **************************** ************:********:*.*:*****:**** *****:***.*** *****:****************:***:*****:********.*******.********* * *::* * ******:****:* *:********:******.**:**** *.****** ** **:******* ** ::**.* **** ** ***::*.:*:**:**::*:*.*::*** *:.*:*****:**:.*:: ***************:****.***:*******::******** ***************************:***** **.******* ::* *:. *.:..*:::*::*****.****:**************:.** * : *:****.***.*****:*:* ********:. .*:*:*:*:**:*** :*:::*.: *** .*:* ..:* ..::**:** **::: :*: **.: * ** :** :*.***. *::.****::. *** *** ::.:: * . *: **:** : .**.:* *:*::** .:*: *. *: : *. : :* *:*.*.** ***::* :.* : :*****:*. :* .** **** .* ***:. *** **...*:: :* .*:* .*:**.*** *:********.**.**.**:* . . ***:***.:*:*** **:**** **.****::***:***:*::* * *:: * *** *** :*:**.:* ************** * :* *:*** ***** : . *:: : :: ", "identical_positions": 608, "similar_positions": 209, "identity": "61.23%" }, { "cls_id": "homologset.agr.MGI:1316742", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97590-1", "uniprot_id": "LEG7_RAT", "id": "P97590-1", "name": "Galectin-7", "aln": "------------------------------------------------------------------------------------------------------------------------------------MSATHHKTPLPQGVRLGTVMRIRGVVPDQAGRFHVNLLCGEEQE----ADAALHFNPRLDTSEVVFNTKQQGKWGREERGTGIPFQ--RGQPFEVLIITTEEGFKTVIGDDEYLHFHHRMPSSNVRSVEVGGDVQLHSVKIF-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O54974-1", "uniprot_id": "LEG7_MOUSE", "id": "O54974-1", "name": "Galectin-7", "aln": "------------------------------------------------------------------------------------------------------------------------------------MSATHHKTSLPQGVRVGTVMRIRGLVPDQAGRFHVNLLCGEEQG----ADAALHFNPRLDTSEVVFNTKQQGKWGREERGTGIPFQ--RGQPFEVLLIATEEGFKAVVGDDEYLHFHHRLPPARVRLVEVGGDVQLHSLNIF-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P47929-1", "uniprot_id": "LEG7_HUMAN", "id": "P47929-1", "name": "Galectin-7", "aln": "------------------------------------------------------------------------------------------------------------------------------------MSNVPHKSSLPEGIRPGTVLRIRGLVPPNASRFHVNLLCGEEQG----SDAALHFNPRLDTSEVVFNSKEQGSWGREERGPGVPFQ--RGQPFEVLIIASDDGFKAVVGDAQYHHFRHRLPLARVRLVEVGGDVQLDSVRIF-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VPI6-1", "uniprot_id": "Q9VPI6_DROME", "id": "Q9VPI6-1", "name": "Galectin", "aln": "MTAIILLACHSVRELVDLSDALWQNTFNIERSLNYYRIKRRLELFRFHCRELWLRQVSKTSDPMHRKAGIDFAAIEAGADCVLNMDAFDDTTTELHKRFLQAEGTRPFPSDCISGIEVVDGNEFKASFYEYADAVPKYFNDQIGKLSEGISFTVTGNLSVNCERFSINLVYNNDS-----RDVALHINPRLPQNYIVRNTKVQDIWGNEEVSSALPFLLSRGEEFSIQVLVTEACYMISVNGQHFAAYTHRIPYRDVRILEVKGDVSNVEMKRTLVLKYPERLPQSEANNIELHIDDGINEIDASVEETVKIPHEWCIISAPNTQSDSSPKRNNSSNDLGLTLPYYG-ALPPNSLVDGRCLKIEGRVRLLPHSFYINLQQGQDIWPHPVIAFHLNPRFSKASSGAIGKAVVCRNAWLNGAWAQEERSEFDTNFRPGRSFCLAIVCTKTSFEVYVNRQFMTDFKYKVSPEVVDTVYIQGDVKLWNVTLEKNQMIKGKNMRVYQN----PWFFSE------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VPI7-1", "uniprot_id": "Q9VPI7_DROME", "id": "Q9VPI7-1", "name": "Galectin", "aln": "------------------------------------------------------------------------------------MSVYPGACTVALRRVMDAMS---------------------LFYEKRSEAHRRKHFKVIQCPRPGLCFVFHGMILMACEHFVIDFLTKQGSEICEECDVLLQIGSRLPQNYITRNSRLKGKWGPEENSSYLTFQLNRGKSFWMQILLTEECFFISVNGYHFAKYFHRMPYRWLEAVDVLGDVSDIVIDTYYVSEYPIRLTHS--------LPRPIPHSNKLPRDGENVETEWMVLSSLAKMSSKKFLYQPS-----LPLPFYGKLLKENFLIEGSSLRIEGRVRLMPQRFSIAFQKGQEIWPQPTVSFYFSPCFLRSRHDKIGTAIITRRAYLNGDWVNCTVSRLNTSLRPGGAFVIVIACRDSYYELFVNNRSLFHFKYQMRPECVDIVNIRGDIKLWEVAIQGNTTYKKPKVRSAMERAISAWKRAEIPQLQI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * : . * : . :* :::: : . *. *::..** . :. *:: :. ** ** .. :.* **: * : :: :: : :.. .: : **:* :. ::* ***. : ", "identical_positions": 23, "similar_positions": 48, "identity": "4.43%" }, { "cls_id": "homologset.agr.MGI:1316743", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q91Y74-1", "uniprot_id": "SIA4C_MOUSE", "id": "Q91Y74-1", "name": "CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4", "aln": "MTSKSHWKLLALALVLVVVMVWYSISREDRYIEFFYFPISEKKEPCFQGEAERQASKIFGNRSREQPIFLQLKDYFWVKTPSTYELPFGTKGSEDLLLRVLAITSYSIPESIKSLECRRCVVVGNGHRLRNSSLGGVINKYDVVIRLNNAPVAGYEGDVGSKTTIRLFYPESAHFDPKIENNPDTLLVLVAFKAMDFHWIETILSDKKRVRKGFWKQPPLIWDVNPKQVRILNPFFMEIAADKLLSLPIQQPRKIKQKPTTGLLAITLALHLCDLVHIAGFGYPDASNKKQTIHYYEQITLKSMAGSGHNVSQEAIAIKRMLEMGAVKNLTYF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P61131-1", "uniprot_id": "SIA4C_RAT", "id": "P61131-1", "name": "CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4", "aln": "MTSKSHWKLLALALVLVVVMVWYSISREDRYIEFFYFPVSEKKEPCFQGEAERQASKIFGNHSREQPIFLQLKDYFWVKTPSAYELPFGTKGSEDLLLRVLAITSYSIPESIQSLECRRCVVVGNGHRLKNSSLGGVINKYDVVIRLNNAPVAGYEGDVGSKTTIRLFYPESAHFDPKIENNPDTLLVLVAFKAMDFHWIETILSDKKRVRKGFWKQPPLIWDVNPKQIRILNPFFMEIAADKLLSLPIQQPRKIKQKPTTGLLAITLALHLCDLVHIAGFGYPDAYNKKQTIHYYEQITLKSMAGSGHNVSQEAVAIKRMLEMGAVKNLTYF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q11206-1", "uniprot_id": "SIA4C_HUMAN", "id": "Q11206-1", "name": "CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4", "aln": "MVSKSRWKLLAMLALVLVVMVWYSISREDRYIELFYFPIPEKKEPCLQGEAESKASKLFGNYSRDQPIFLRLEDYFWVKTPSAYELPYGTKGSEDLLLRVLAITSSSIPKNIQSLRCRRCVVVGNGHRLRNSSLGDAINKYDVVIRLNNAPVAGYEGDVGSKTTMRLFYPESAHFDPKVENNPDTLLVLVAFKAMDFHWIETILSDKKRVRKGFWKQPPLIWDVNPKQIRILNPFFMEIAADKLLSLPMQQPRKIKQKPTTGLLAITLALHLCDLVHIAGFGYPDAYNKKQTIHYYEQITLKSMAGSGHNVSQEALAIKRMLEMGAIKNLTSF", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.***:*****: :::****************:****:.******:***** :***:*** **:*****:*:*********:****:***************** ***:.*:**.*************:*****..***************************:*************:*************************************************:*******************:************************************* ****************************:**********:**** *", "identical_positions": 296, "similar_positions": 30, "identity": "88.89%" }, { "cls_id": "homologset.agr.MGI:1316745", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9PTU9-1", "uniprot_id": "E9PTU9_RAT", "id": "E9PTU9-1", "name": "", "aln": "MALLTILRIL-LWGMVLFMEHKVQMAKVEWPSTTLLAENPTLPSSLDLAKEAPGKE-MKQWPQGYPLRYMLKLYQRSADPHGHPRENRTIGAKMVRLIKPSASAMRLLRGPWHIQTLDFPLASNEVAYQLIRATVVYRHQLHLVHYHLSCHVEPWVPKCRTKHFPS-KSGSAKPSSVSKAWREMNITHCIQQKLWNRKGRRVLRLRFMCQQQKGNETLELRWHGMTSLDVAFLLLYFNDTDESA-QAKLLARGQEELTDRESPFLMRSVRQTCSIASDVPCPSQEQDRSVNNQCSLHPYKVSFHQLGWDHWIIAPRLYTPNYCKGICTGVLPYGLNSPNHAIIQSLVNELVNRSVPQLSCVPYKFLPMSILLIEANGSILYKEYEGMIAQSCTCR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z0L4-1", "uniprot_id": "BMP15_MOUSE", "id": "Q9Z0L4-1", "name": "Bone morphogenetic protein 15", "aln": "MALLTILRIL-LWGVVLFMEQRVQMAKPGWPSTALLADDPTLPSILDLAKEAPGKE-MKQWPQGYPLRYMLKLYHRSADPHGHPRENRTIGAKMVRLVKPSANTVRPPRGSWHVQTLDFPLASNQVAYELIRATVVYRHQLHLVNYHLSCHVETWVPKCRTKHLPSSKSGSSKPSPMSKAWTEIDITHCIQQKLWNRKGRSVLRLRFMCQQQKGNETREFRWHGMTSLDVAFLLLYFNDTDDRV-QGKLLARGQEELTDRESSFLMRSVRQACSIESDASCPSQEHDGSVNNQCSLHPYKVSFHQLGWDHWIIAPRLYTPNYCKGICTRVLPYGLNSPNHAIIQSLVNELVNHSVPQPSCVPYNFLPMSILLIETNGSILYKEYEGMIAQSCTCR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95972-1", "uniprot_id": "BMP15_HUMAN", "id": "O95972-1", "name": "Bone morphogenetic protein 15", "aln": "MVLLSILRILFLCELVLFMEHRAQMAEGGQSSIALLAEAPTLPLIEELLEESPGEQPRKPRLLGHSLRYMLELYRRSADSHGHPRENRTIGATMVRLVKPLTNVARPHRGTWHIQILGFPLRPNRGLYQLVRATVVYRHHLQLTRFNLSCHVEPWVQKNPTNHFPSSEGDSSKPSLMSNAWKEMDITQLVQQRFWNNKGHRILRLRFMCQQQKDSGGLEL-WHGTSSLDIAFLLLYFNDTHKSIRKAKFLPRGMEEFMERES--LLRRTRQADGISAEVTASSSKHSGPENNQCSLHPFQISFRQLGWDHWIIAPPFYTPNYCKGTCLRVLRDGLNSPNHAIIQNLINQLVDQSVPRPSCVPYKYVPISVLMIEANGSILYKEYEGMIAESCTCR", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.**:***** * :*****::.***: .* :***: **** :* :*:**:: * *:.*****:**:****.************.****:** :.. * **.**:* *.*** .*. *:*:********:*:*..::******.** * *:*:** :..*:*** :*:** *::**: :**::**.**: :***********.. *: *** :***:**********.. :.*:*.** **: :*** *:* .**: .* ::....*.::. . ********:::**:*********** :******** * ** ***********.*:*:**::***: *****:::*:*:*:**:**************:*****", "identical_positions": 234, "similar_positions": 103, "identity": "59.24%" }, { "cls_id": "homologset.agr.MGI:1321119", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88445-1", "uniprot_id": "AURKC_MOUSE", "id": "O88445-1", "name": "Aurora kinase C", "aln": "------------------------------------------------------------------------------------------------------------------------------------------MEPSTSTRKHFTINDFEIGRPLGRGKFGRVYLARLKENHFIVALKVLFKSEIEKEGLEHQLRREVEIQAHLQHRNILRLYNYFYDDTRIYLILEYAPGGELYKELQRH--QKLDQQRTATIIQELSDALTYCHEKKVIHRDIKPENLLLGLNGEVKISDFGWSVHTP-SLRRKTMCGTLDYLPPEMIAQKPYNEMVDLWCIGVLCYELLVGKPPFESSTSSETYRRIRQVDFKFPSSVPAGAQDLISKLLRYHPSERLSLAQVLKHPWVREHSRRVLP-C------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4AD76-1", "uniprot_id": "D4AD76_RAT", "id": "D4AD76-1", "name": "non-specific serine/threonine protein kinase", "aln": "-------------------------------------------------------------------------------------------MLEISRLLVSLGYPVPNLELLCQREQVQEPWTVVKSPSESTSLATGQMEPSTSTKKHFTINDFEIGRPLGRGKFGRVYLARLKENHFIVALKVLFKSEIGKEGLEHQLRREVEIQSHLQHPNILRLYNYFYDDSRVYLILEYAPRGELYKELQRN--QKLNQQRTATIIEELSDALIYCHRNKVIHRDLKPENLLLGLKGEVKIADFGWSVHTP-SLRRKTMCGTLDYLPPEMIEGKSYNETVDLWCIGVLCYELLVGKPPFESSTSSETCRRICQVDFRFPSSMPAGAQDLISKLLRHHPSERLSLAQVLKHPWVRKHSQRMLPPCAQMAS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UQB9-1", "uniprot_id": "AURKC_HUMAN", "id": "Q9UQB9-1", "name": "Aurora kinase C", "aln": "--------------------------------------------------------------------------------------------MSSPRAVVQLGKAQPAGEELATANQTAQ-------------------QPSSPAMRRLTVDDFEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQHPNILRLYNYFHDARRVYLILEYAPRGELYKELQKS--EKLDEQRTATIIEELADALTYCHDKKVIHRDIKPENLLLGFRGEVKIADFGWSVHTP-SLRRKTMCGTLDYLPPEMIEGRTYDEKVDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDVRFPLSMPLGARDLISRLLRYQPLERLPLAQILKHPWVQAHSRRVLPPCAQMAS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NW76-1", "uniprot_id": "AURKB_DANRE", "id": "Q6NW76-1", "name": "Aurora kinase B", "aln": "--------------------------------------------------------------------------------------------MQNKENREPRVQQTPSAGVGPLRVEMNPDTHAVSGPG---------RVPVKSNSKVLSIDDFDIGRPLGKGKFGNVYLARERKLKVVIALKVLFKSQMVKEGVEHQLRREIEIQSHLRHPNILRFYNYFHDDTRVFLILEYAPRGEMYKELQRY--GRFDDQRTATYMEEVSDALQYCHEKKVIHRDIKPENLLLGYRGELKIADFGWSVHAP-SLRRRTMCGTLDYLPPEMIEGHSHDEKVDLWSIGVLCYECLVGNPPFETASHAETYKRITKVDLQFPKLVSEGARDLISKLLRHSPSMRLPLRSVMEHPWVKANSRRVLPPVCSSEPH", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VGF9-1", "uniprot_id": "Q9VGF9_DROME", "id": "Q9VGF9-1", "name": "Aurora kinase", "aln": "MSHPSDHVLRPKENAPHRMPEKSAAVHNMQKNLLLGKKPNSENMAPASKPLPGSSGALIRKPGLGGSNSIASSEGNNFQKPMVPSVKKTTSEFAAPAPVAPIKKPESLSKQKPTAASSESSKELGAASSSAEKEKTKTETQPQKPKKTWELNNFDIGRLLGRGKFGNVYLAREKESQFVVALKVLFKRQIGESNVEHQVRREIEIQSHLRHPHILRLYAYFHDDVRIYLILEYAPQGTLFNALQAQPMKRFDERQSATYIQALCSALLYLHERDIIHRDIKPENLLLGHKGVLKIADFGWSVHEP-NSMRMTLCGTVDYLPPEMVQGKPHTKNVDLWSLGVLCFELLVGHAPFYSKNYDETYKKILKVDYKLPEHISKAASHLISKLLVLNPQHRLPLDQVMVHPWILAHTQ------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38991-1", "uniprot_id": "AURK_YEAST", "id": "P38991-1", "name": "Aurora kinase", "aln": "----------------------------MQRNSLVNIKLNANSPSKKTTTRPNTSR-----------------INKPWRISHSPQQRNPNSKIPSPVREKLNRLPVNNKKFLDMESSKIPSPIRKATSS-----KMIHENKKLPKFKSLSLDDFELGKKLGKGKFGKVYCVRHRSTGYICALKVMEKEEIIKYNLQKQFRREVEIQTSLNHPNLTKSYGYFHDEKRVYLLMEYLVNGEMYKLLRLH--GPFNDILASDYIYQIANALDYMHKKNIIHRDIKPENILIGFNNVIKLTDFGWSIINPPENRRKTVCGTIDYLSPEMVESREYDHTIDAWALGVLAFELLTGAPPFEEEMKDTTYKRIAALDIKMPSNISQDAQDLILKLLKYDPKDRMRLGDVKMHPWILRNKPFWENKRL-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :::*::*: **:****.** .* :. : ****: * :: : .:::*.***:***: *.* :: : * **:* *::*::** * ::: *: ::: :: : :..** * * ..:****:****:*:* .. :*::*****: * . * *:***:***.***: : : . :* *.:***.:* *.* .** * ::* :* ::* :. * .** :** * *: * .: ***: :. ", "identical_positions": 92, "similar_positions": 88, "identity": "21.7%" }, { "cls_id": "homologset.agr.MGI:1321133", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62959-1", "uniprot_id": "HINT1_RAT", "id": "P62959-1", "name": "Adenosine 5'-monophosphoramidase HINT1", "aln": "-----MADEIAKAQVAQPG---GDTIFGKIIRKEIPAKIIFEDDRCLAFHDISPQAPTHFLVIPKKHISQISVADDDDESLLGHLMIVGKKCAADLGLKRGYRMVVNEGADGGQSVYHIHLHVLGGRQ------MNWPPG----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70349-1", "uniprot_id": "HINT1_MOUSE", "id": "P70349-1", "name": "Adenosine 5'-monophosphoramidase HINT1", "aln": "-----MADEIAKAQVAQPG---GDTIFGKIIRKEIPAKIIFEDDRCLAFHDISPQAPTHFLVIPKKHISQISVADDDDESLLGHLMIVGKKCAADLGLKRGYRMVVNEGADGGQSVYHIHLHVLGGRQ------MNWPPG----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49773-1", "uniprot_id": "HINT1_HUMAN", "id": "P49773-1", "name": "Adenosine 5'-monophosphoramidase HINT1", "aln": "-----MADEIAKAQVARPG---GDTIFGKIIRKEIPAKIIFEDDRCLAFHDISPQAPTHFLVIPKKHISQISVAEDDDESLLGHLMIVGKKCAADLGLNKGYRMVVNEGSDGGQSVYHVHLHVLGGRQ------MHWPPG----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q04344-1", "uniprot_id": "HNT1_YEAST", "id": "Q04344-1", "name": "Adenosine 5'-monophosphoramidase HNT1", "aln": "MEPLISAPYLTTTKMSAPATLDAACIFCKIIKSEIPSFKLIETKYSYAFLDIQPTAEGHALIIPKYHGAKLHDIPD---EFLTDAMPIAKRLAKAMKLDT-YNVLQNNGKIAHQEVDHVHFHLIPKRDEKSGLIVGWPAQETDFDKLGKLHKELLAKLEGSD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * ::.:::: *. . ** ***:.***: ::* . . ** **.* * * *:*** * ::: * .:* . * :.*: * : *. *.:: *:* . *.* *:*:*:: *: : **. ", "identical_positions": 40, "similar_positions": 42, "identity": "24.69%" }, { "cls_id": "homologset.agr.MGI:1321151", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B1AUH1-1", "uniprot_id": "PTPRU_MOUSE", "id": "B1AUH1-1", "name": "Receptor-type tyrosine-protein phosphatase U", "aln": "MARAQALVLALTFQFCAPETETPAAGCTFEEASDPVVPCEFSQAQYDDFQWEQVRIHPGTRTPEDLPHGAYLMVNASQHAPGQRAHIIFQTLSENDTHCVQFSYFLYSRDGHSPGTLGVYVRVNGGPLGSAVWNMTGSHGRQWHQAELAVSTFWPNEYQVLFEALISPDHKGYIGLDDILLFSYPCAKAPHFSRLGDVEVNAGQNASFQCMAAGRAAEAEHFFLQRQSGVLVPAAGVRHISHRRFLATFPLASVGRSEQDLYRCVSQAPRGAGVSNFAELIVKEPPTPIAPPQLLRAGPTYLIIQLNTNSIIGDGPIVRKEIEYRMARGPWAEVHAVNLQTYKLWHLDPDTEYEISVLLTRPGDGGTGRPGPPLISRTKCAEPTRAPKGLAFAEIQARQLTLQWEPLGYNVTRCHTYAVSLCYRYTLG---GSHNQTIRECVKMERGASRYTIKNLLPFRNIHVRLILTNPEGRKEGKEVTFQTDEDVPGGIAAESLTFTPLEDMIFLKWEEPQEPNGLITQYEISYQSIESSDPAVNVPGPRRTISKLRNETYHVFSNLHPGTTYLFSVRARTSKGFGQAALTEITTNISAPSFDYADMPSPLGESENTITVLLRPAQGRGAPISVYQVVVEEERPRRLRREPGAQDCFSVPLTFETALARGLVHYFGAELAASSLLEAMPFTVGDNQTYRGFWNPPLEPRKAYLIYFQAASHLKGETRLNCIRIARKAACKESKRPLEVSQRSEEMGLILGICAGGLAVLILLLGAIIVIIRKGRDRYAYSYYP-KPVNMTKATVNYRQEKTHMMSAVDRSFTDQSTLQEDERLGLSFMDAPGYSPRGDQRSGGVTEASSLLGGSPRRPCGRKGSPYHTGQLHPAVRVADLLQHINQMKTAEGYGFKQEYESFFEGWDATKKKDKLKGGRQEPVSAYDRHHVKLHPMLADPDADYISAN---YID------GYHRSNHFIATQGPKPEMIYDFWRMVWQEQCASIVMITKLVEVGRVKCSRYWPEDSDMYGDIKITLVKTETLAEYVVRTFALERRGYSARHEVRQFHFTAWPEHGVPYHATGLLAFIRRVKASTPPDAGPIVIHCSAGTGRTGCYIVLDVMLDMAECEGVVDIYNCVKTLCSRRVNMIQTEEQYIFIHDAILEACLCGETTIPVNEFKATYREMIRIDPQSNSSQLREEFQTLNSVTPPLDVEECSIALLPRNRDKNRSMDVLPPDRCLPFLISSDGDPNNYINAALTDSYTRSAAFIVTLHPLQSTTPDFWRLVYDYGCTSIVMLNQLNQSNSAWPCLQYWPEPGRQQYGLMEVEFVSGTANEDLVSRVFRVQNSSRLQEGHLLVRHFQFLRWSAYRDTPDSRKAFLHLLAEVDKWQAESGDGRTVVHCLNGGGRSGTFCACATVLEMIRCHSLVDVFFAAKTLRNYKPNMVETMDQYHFCYDVALEYLEALELR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1MAG7-1", "uniprot_id": "F1MAG7_RAT", "id": "F1MAG7-1", "name": "Receptor-type tyrosine-protein phosphatase U", "aln": "MARAQALVLALTFQFCAPETETPAAGCTFEEASDPVVPCEFSQAQYDDFQWEQVRIHPGTRTPADLPHGAYLMVNASQHAPGQRAHIIFQTLSENDTHCVQFSYFLFSRDGHSPGTLGVYVRVNGGPLGSAVWNMTGSHGRQWHQAELAVSTFWPNEYQVLFEALISPDHKGYIGLDDILLFSHPCAKAPHFSRLGDVEVNAGQNASFQCMAAGRAAEAERFFLQRQSGVLVPAAGVRHISHRRFLATFPLASVGRSEQDLYRCVSQAPRGAGVSNFAELIVKEPPTPIAPPQLLRAGPTYLIIQLNTNSIIGDGPIVRKEIEYRMARGPWAEVHAVNLQTYKLWHLDPDTEYEISVLLTRPGDGGTGRPGPPLLSRTKCAEPTRAPKGLAFAEIQARQLTLQWEPLGYNVTRCHTYAVSLCYHYTLG---GSHNQTIRECVKMERGASRYTIKNLLPFRNVHVRLILTNPEGRKEGKEVTFQTDEDVPGGIAAESLTFTPLEDMIFLKWEEPQEPNGLITQYEISYQSIESSDPAVNVPGPRRTISKLRNETYHVFSNLQPGTTYLFSVRARTSKGFGQAALTEITTNISAPSFDYADMPSPLGESENTITVLLRPAQGRGAPISVYQVVVEEERPRRLRREPGGQDCFSVPLTFETALARGLVHYFGAELAASSLLEAMPFTVGDNQTYRGFWNPPLEPRKAYLIYFQAASHLKGETRLNCIRIARKAACKESKRPLEVSQRSEEMGLILGICAGGLAVLILLLGAIIIIIRKGRDRYAYSYYP-KPVNMAKATVNYRQEKTHMMTAVDRSFTDQSTLQEDERLGLSFMDAPGYSPRGDQRSSGVTEASSLLGGSPRRPCGRKGSPYHTGQLHPAVRVADLLQHINQMKTAEGYGFKQEYESFFEGWDATKKKDKLKSGRQEPVSAYDRHRVKLHPMLGDPDADYISAN---YIDIRINRQGYHRSNHFIATQGPKPEMIYDFWRMVWQEQCVSVVMISKLVEVGRVKCSRYWPEDSDMYGDIKITLVKTETLAEYVVRTFALERRGYSARHEVRQFHFTAWPEHGVPYHATGLLAFIRRVKASTPPDAGPVVIHCSAGTGRTGCYIVLDVMLDMAECEGVVDIYNCVKTLCSRRVNMIQTEEQYIFIHDAILEACLCGETTIPVNEFKATYREMIRIDPQSNSSQLREEFQTLNSVTPPLDVEECSIALLPRNRDKNRSMDVLPPDRCLPFLISSDGDPNNYINAALTDSYTRSAAFIVTLHPLQSTTPDFWRLVYDYGCTSIVMLNQLNQSNSAWPCLQYWPEPGRQQYGLMEVEFVSGTANEDLVSRVFRVQNSSRLQEGHLLVRHFQFLRWSAYRDTPDSRKAFLHLLAEVDKWQAESGDGRTVVHCLNGGGRSGTFCACATVLEMIRCHSLVDVFFAAKTLRNYKPNMVETMDQYHFCYDVALEYLEALELR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q92729-1", "uniprot_id": "PTPRU_HUMAN", "id": "Q92729-1", "name": "Receptor-type tyrosine-protein phosphatase U", "aln": "MARAQALVLALTFQLCAPETETPAAGCTFEEASDPAVPCEYSQAQYDDFQWEQVRIHPGTRAPADLPHGSYLMVNTSQHAPGQRAHVIFQSLSENDTHCVQFSYFLYSRDGHSPGTLGVYVRVNGGPLGSAVWNMTGSHGRQWHQAELAVSTFWPNEYQVLFEALISPDRRGYMGLDDILLLSYPCAKAPHFSRLGDVEVNAGQNASFQCMAAGRAAEAERFLLQRQSGALVPAAGVRHISHRRFLATFPLAAVSRAEQDLYRCVSQAPRGAGVSNFAELIVKEPPTPIAPPQLLRAGPTYLIIQLNTNSIIGDGPIVRKEIEYRMARGPWAEVHAVSLQTYKLWHLDPDTEYEISVLLTRPGDGGTGRPGPPLISRTKCAEPMRAPKGLAFAEIQARQLTLQWEPLGYNVTRCHTYTVSLCYHYTLG---SSHNQTIRECVKTEQGVSRYTIKNLLPYRNVHVRLVLTNPEGRKEGKEVTFQTDEDVPSGIAAESLTFTPLEDMIFLKWEEPQEPNGLITQYEISYQSIESSDPAVNVPGPRRTISKLRNETYHVFSNLHPGTTYLFSVRARTGKGFGQAALTEITTNISAPSFDYADMPSPLGESENTITVLLRPAQGRGAPISVYQVIVEEERARRLRREPGGQDCFPVPLTFEAALARGLVHYFGAELAASSLPEAMPFTVGDNQTYRGFWNPPLEPRKAYLIYFQAASHLKGETRLNCIRIARKAACKESKRPLEVSQRSEEMGLILGICAGGLAVLILLLGAIIVIIRKGRDHYAYSYYP-KPVNMTKATVNYRQEKTHMMSAVDRSFTDQSTLQEDERLGLSFMDTHGYSTRGDQRSGGVTEASSLLGGSPRRPCGRKGSPYHTGQLHPAVRVADLLQHINQMKTAEGYGFKQEYESFFEGWDATKKKDKVKGSRQEPMPAYDRHRVKLHPMLGDPNADYINAN---YID------GYHRSNHFIATQGPKPEMVYDFWRMVWQEHCSSIVMITKLVEVGRVKCSRYWPEDSDTYGDIKIMLVKTETLAEYVVRTFALERRGYSARHEVRQFHFTAWPEHGVPYHATGLLAFIRRVKASTPPDAGPIVIHCSAGTGRTGCYIVLDVMLDMAECEGVVDIYNCVKTLCSRRVNMIQTEEQYIFIHDAILEACLCGETTIPVSEFKATYKEMIRIDPQSNSSQLREEFQTLNSVTPPLDVEECSIALLPRNRDKNRSMDVLPPDRCLPFLISTDGDSNNYINAALTDSYTRSAAFIVTLHPLQSTTPDFWRLVYDYGCTSIVMLNQLNQSNSAWPCLQYWPEPGRQQYGLMEVEFMSGTADEDLVARVFRVQNISRLQEGHLLVRHFQFLRWSAYRDTPDSKKAFLHLLAEVDKWQAESGDGRTIVHCLNGGGRSGTFCACATVLEMIRCHNLVDVFFAAKTLRNYKPNMVETMDQYHFCYDVALEYLEGLESR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B3DK56-1", "uniprot_id": "PTPRU_DANRE", "id": "B3DK56-1", "name": "Receptor-type tyrosine-protein phosphatase U", "aln": "-MNTCAFLLILAVQIHADSVEGPTAGCTFDEDSDPSL-CEFSQGEEDDFDWQLFRAHASPHSTSDLLRGSYMMVNSSQHAAGQRAQLLLQTLSENDTHCVQFSYFLYSRDGHSPGALRVYVRVNGGPLGIPVWNVSGSRGRQWHQVELAVSTFWPNEYQILLEATVD--RKGYIAVDDILLLNYPCYKAPHFSRLGDVEVNAGQNATFQCVAAGRPSEAEKFLLERHNGEVSSGGSVKHLGRNRFAVSFQLEDVQKPEQDLYRCVTQSSRGSGVSNFAELIVKVPPSPIAPPQLLRAGSTYLIIQLNTNSILGDGPIIRREIEYRASLAPWSEILGVNMVTYKLWHLDPDTEYHISVLLTRPGEGGTGPPGPPLISRTKCAEPMRALRGLRASEIQSRQLTLQWEVPAFNLTRCHTYSVSLCYRYTTAGGGGGHNTTVRECLAVEHNTSRFTLRDLPPFHTIQIRLALANTEGKKEGKEVMFQTEEDIPGGIAPESLTFTPLEDMIFLKWEEPVEPNGLITQYEISYQSIESSDPGINVPGPRRTVSKLKNETYHMFSNLHPGTTYLISVRARTAKGFGQTALTEITTNISAPTFDYGDMPSPLSETENTITVLLRPAQGRGAPVSTYQVVVEEEAGRKVKRELGIQDCFPIPTSHGEAQARGAPHYYTAELPPSSLSEATPFTVGDNHTYNGYWNSPLDPRKNYLVYFQAMSNFRGETRINCIRIARKAACKDHQRALEVTQRSEEMGLILGVCAGGLVVLILLLGAIIIIIKKGRDYYSYSYYPRKPGNMNKTPITYRQEKSNMMGSMERSFTDQSTLQEDERMALSFMDTHTCSTRSDPRSS-MNESSSLLGGSPRRQCGRKGSPYHTGQLHPAVRVADLLQHINQMKTAEGYGFKQEYESFFDGWDINKKKDKTKG-RHDTLMGYDRHRVKLHPLLGDPNSDYINAN---YID------GYHRSNHFIATQGPKQETVYDFWRMVWQENCFSIVMITKLVEVGRVKCCKYWPDESEMYGDIKITLLKTETLAEYTVRTFALERRGYSAKHEVCQFHFTSWPEHGVPYHATGLLAFIRRVKTSTPLDAGPVVVHCSVGAGRTGCYIVLDVMLDMAECEGVVDIYNCVKTLCSRRINMIQTEEQYIFIHDAILEACLCGETAIPVNEFALAYKEMLRVDSQSNSSQLREEFQTLNSVTPHLDVEECSIALLPRNREKNRSMDVLPPDRALAFLVTTEGESNNYINAALMDSFHRPAAFIVTPHPLPGTTSDFWRLVFDYGCTSVVMLNQLNQSNSAWPCVQYWPEPGLQQYGPMQVEFLSMSADEDIITRLFRVKNVTRLQEGQLVVCQFQFLRWSAYRDVPDSKKAFLNLLASVQKWQRECGEGRTVVHCLNGGGRSGTYCASNILMEMIQYQNIVDVFYAVKTLRNAKPNMVETLEQYRFCYELVLEYLDCLEVR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P40048-1", "uniprot_id": "PTP3_YEAST", "id": "P40048-1", "name": "Tyrosine-protein phosphatase 3", "aln": "-------------------------------------------------------MKDSVDCPSILPTDRTSVLSETSTLVGSSSHVYSRHAPMNSYHNSMNSNIYHSPKASSP-------------------------------------------------------LVSYKTSSPVLLKRATAPVLPSFKPKEQRYNKPQGCSLITAVELG------------KIIETLPDEKVLLLDVR----PFTEHAKSIITNSIHVCLPSTLLRRKNFTFSKLLDNLTPSEQSVLKSKLAIDNLRIIIYDSTANQTESSVS----------------LPCYGIASKLIEFDTNVKKTVSILMCG-------FPQFKILFPDHINTNTFNSDCISSAEPKSP----------------------------------------KTNLMNSLHNTAPHMTATTPLSSPQMNLKLKVPDDSRSD-----------------------------HSNFSSSPSPRNVLSDSPMSSSSPISALFKFQLPAPQTNIN---------------------------------------------QMFKFSQNEEIMG---------------LETYLSAVNIKEEHERWYNNDSAKKSLQNFQFPKNQNSLEKDTNKDKLGFQIRYENLSKNYEKEVIDSVIPEWFQHLMSIPKIELVSQFQKLDFLE-----------------KRRLNHSVSFRKKENSFILEKPSS------------------------YP---------------EQLTSTSSSTIMPPKFPDVNKVQKRSHSQPIFTQYSKYKSMLSLESDSDSESDDVIISSGVELGAKNRYKDIFPYEHSRVILKKGLQSSKGIKHSHSTSDGGILDNYIN-----------------------ANYLSLPRFSVEQNSSFQTTTTTT------------RRVRYIATQAPMPSTVHDFYTCILNNGVPLVLSLTNDFENGIEKCYRYWQEGN--YNGIHVKLLEKKILKMPSTTSMRKNTMG----------------TQNSSLYSAGVQGNSSNYSTDNDNDN----------DNNNNNNNNSNIAVTAAACDDDDDDDDDAILIRKILLTYHDQEKPYELLQIQVKNWPDLGTLLNPISILQAINVKNHIIDTLFARN--------------YYQNDQLPTILVHCSAGCGRTGTLCTIDSILSNFEMFEMLQKEFVKLKYPAKLFDPISWTINIFRKQ----------------RISMVQNINQFIFIYDCLLFYFR--------------------------LRLDDITERTDG-------------------------------------------------DGSNK-----------DNISLSALIEQIEKLEILQTFVDDKLKELPQ------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . * . ::. :. *. ::: : . *. * * : .* .. ** .* . :** .. * *. : :. : : .: * : . * :. . .* :.:: *:..: .*::*: : .*: : : * . ** ::.: :..: : ** .:*.:.: :*:*: * :: : : :* :: : : . : : * . ::.* * .:. :.. . ::... .*..:::: :* .* *: .::*.*: .:. *.:.: . :. : :*. :: *.* . : * .* . . :: ..* : * *. . : : *: : ** . :. . : .*: *.:* .:** :. *. : .: : .*.* ..:*: .: * : .. . .*. .*:..:: .* . .:: *. * : . ** : :* :.. . :.::: : :.* : : ::.: .:. * ::****.* . ::**: : :: :: ::: .* * ** :** : . *..*:: *::.: * . :: : * :. . :::*: . . .:.. * .... :: : * *:. * : . : . :. : *: * ::: : : * *:. : : :*. . : :: . *: . .*: : . * *. : : ::::: . . :: :. . : *::::** : *: :: . :*:.: :. :* :*..: : * ::: : : *:. : :: : * ", "identical_positions": 113, "similar_positions": 350, "identity": "7.75%" }, { "cls_id": "homologset.agr.MGI:1321152", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99M80-1", "uniprot_id": "PTPRT_MOUSE", "id": "Q99M80-1", "name": "Receptor-type tyrosine-protein phosphatase T", "aln": "MGSLGGLALCLLRLLLLGLQRPPLPGAGAQSAAGGCSFDEHYSNCGYSVALGTNGFTWEQINTWEKPMLDPAVPTGSFMMVNSSGRASGQKAHLLLPTLKENDTHCIDFHYYFSSRDRSSPGALNVYVKVNGGPQGNPVWNVSGVVTEGWVKAELAISTFWPHFYQVIFESVSLKGHPGYIAVDEVRVLAHPCRKAPHFLRLQNVEVNVGQNATFQCIAGGKWSQHDKLWLQQWNGRDTALMVTRVVNHRRFSATVSVADTSQRSISKYRCVIRSDGGSGVSNYAELIVKEPPTPIAPPELLAVGATYLWIKPNANSIIGDGPIILKEVEYRTTTGTWAETHIVDSPNYKLWHLDPDVEYEIRVLLTRPGEGGTGPPGPPLTTRTKCADPVHGPQNVEIVDIRARQLTLQWEPFGYAVTRCHSYNLTVQYQYVFNQQQYEAEEVIQTSSHYTLRGLRPFMTIRLRLLLSNPEGRMESEELVVQTEEDVPGAVPLESIQGGPFEEKIYIQWKPPNETNGVITLYEINYKAVGSLDPSADLSSQRGKVFKLRNETHHLFVGLYPGTTYSFTIKASTAKGFGPPVTTRIATKISAPSMPEYDADTPLNETDTTITVMLKPAQSRGAPVSVYQLVVKEERLQKSRRAADIIECFSVPVSYRNASNLDSLHYFAAELKPSNLPVTQPFTVGDNKTYNGYWNPPLSPLKSYSIYFQALSKANGETKINCVRLATKGAPMGSAQVTPGTPLCLLTTASTQNSNTVEPEKQVDNTVKMAGVIAGLLMFIIILLGVMLTIKRR---------------------KLAKKQKETQSG-AQREMGPVASTDKPTAKLGTNRNDEGFSSSSQDVNGFT-------------------------------------DGSRGELSQPTLTIQTHPYRTCDPVEMSYPRDQFQPAIRVADLLQHITQMKRGQGYGFKEEYEALPEGQTASWDTAKEDENRNKNRYGNIISY---DHSRVRLLVLDGD--PHSDYINANYIDGYHRPRHYIATQGPMQETVKDFWRMIWQ---ENSASIVMVTNLVEVGR--------------------VKCVRYWPDDTEVYGDIKVTLIETEPLAEYVIRTFTVQKKGYHEIRELRLFHFTSWPDHGVPCYATGLLGFVRQVKFLNPPEAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLYYNISRLDPQTNSSQIKDEFQTLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFLISVDGESSNYINAALMDSHKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNEMDTAQLCMQYWPEKTSGCYGPIQVEFVSADIDEDIIHRIFRICNMARPQDGYRIVQHLQYIGWPAYRDTPPSKRSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIVKTLRNNKSNMVETLEQYKFVYEVALEYLSSF----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AFL3-1", "uniprot_id": "A0A8I6AFL3_RAT", "id": "A0A8I6AFL3-1", "name": "protein-tyrosine-phosphatase", "aln": "MGSLGALALCLLRLLLLGLQRPPLPGAGAQSAAGGCSFDEHYSNCGYSVALGTNGFTWEQINTWEKPMLDPAVPTGSFMMVNSSGRASGQKAHLLLPTLKENDTHCIDFHYYFSSRDRSSPGALNVYVKVNGGPQGNPVWNVSGVVTEGWVKAELAISTFWPHFYQVIFESVSLKGHPGYIAVDEVRVLAHPCRKAPHFLRLQNVEVNVGQNATFQCIAGGKWSQHDKLWLQQWNGRDTALMVTRVVNHRRFSATVSVADTSQRSVSKYRCVIRSDGGSGVSNYAELIVKEPPTPIAPPELLAVGATYLWIKPNANSIIGDGPIILKEVEYRTTTGTWAETHIVDSPNYKLWHLDPDVEYEIRVLLTRPGEGGTGPPGPPLTTRTKCADPVHGPQNVEIVDIRARQLTLQWEPFGYAVTRCHSYNLTVQYQYVFNQQQYEAEEVIQTSSHYTLRGLRPFMTIRLRLLLSNPEGRMESEELVVQTEEDVPGAVPLESIQGGPFEEKIYIQWKPPNETNGVITLYEINYKAVGSLDPSADLSSQRGKVFKLRNETHHLFVGLYPGTTYSFTIKASTAKGFGPPVTTRIATKISAPSMPEYDADSPLNETDTTITVMLKPAQSRGAPVSVYQLVVKEERLQKSRRAADIIECFSVPVSYRNASNLDSLHYFAAELKPSNLPVTQPFTVGDNKTYNGYWNPPLSPLKSYSIYFQALSKANGETKINCVRLATKG-------------------ASTQNSNTVEPEKQVDNTVKMAGVIAGLLMFIIILLGVMLTIKRR---------------------KLAKKQKETQSG-AQREMGPVASTDKPTTKLSTNRNDEGFSSSSQDVNGFT-------------------------------------DGSRGELSQPTLTIQTHPYRTCDPVEMSYPRDQFQPAIRVADLLQHITQMKRGQGYGFKEEYEALPEGQTASWDTAKEDENRNKNRYGNIISY---DHSRVRLLVLDGD--PHSDYINANYIDGYHRPRHYIATQGPMQETVKDFWRMIWQ---ENSASIVMVTNLVEVGRHPAEHTVGTATLGRAASPGMVKCVRYWPDDTEVYGDIKVTLIETEPLAEYVIRTFTVQKKGYHEIRELRLFHFTSWPDHGVPCYATGLLGFVRQVKFLNPPEAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLYYNISRLDPQTNSSQIKDEFQTLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFLISVDGESSNYINAALMDSHKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNEMDTAQLCMQYWPEKTSGCYGPIQVEFVSADIDEDIIHRIFRICNMARPQDGYRIVQHLQYIGWPAYRDTPPSKRSLLKAVRRLEKWQEEYDGREGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIVKTLRNNKSNMVETLEQYKFVYEVALEYLSSF----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O14522-3", "uniprot_id": "PTPRT_HUMAN", "id": "O14522-3", "name": "Receptor-type tyrosine-protein phosphatase T", "aln": "MASLAALALSLL----LRLQLPPLPGARAQSAAGGCSFDEHYSNCGYSVALGTNGFTWEQINTWEKPMLDQAVPTGSFMMVNSSGRASGQKAHLLLPTLKENDTHCIDFHYYFSSRDRSSPGALNVYVKVNGGPQGNPVWNVSGVVTEGWVKAELAISTFWPHFYQVIFESVSLKGHPGYIAVDEVRVLAHPCRKAPHFLRLQNVEVNVGQNATFQCIAGGKWSQHDKLWLQQWNGRDTALMVTRVVNHRRFSATVSVADTAQRSVSKYRCVIRSDGGSGVSNYAELIVKEPPTPIAPPELLAVGATYLWIKPNANSIIGDGPIILKEVEYRTTTGTWAETHIVDSPNYKLWHLDPDVEYEIRVLLTRPGEGGTGPPGPPLTTRTKCADPVHGPQNVEIVDIRARQLTLQWEPFGYAVTRCHSYNLTVQYQYVFNQQQYEAEEVIQTSSHYTLRGLRPFMTIRLRLLLSNPEGRMESEELVVQTEEDVPGAVPLESIQGGPFEEKIYIQWKPPNETNGVITLYEINYKAVGSLDPSADLSSQRGKVFKLRNETHHLFVGLYPGTTYSFTIKASTAKGFGPPVTTRIATKISAPSMPEYDTDTPLNETDTTITVMLKPAQSRGAPVSVYQLVVKEERLQKSRRAADIIECFSVPVSYRNASSLDSLHYFAAELKPANLPVTQPFTVGDNKTYNGYWNPPLSPLKSYSIYFQALSKANGETKINCVRLATKG-------------------ASTQNSNTVEPEKQVDNTVKMAGVIAGLLMFIIILLGVMLTIKRRRNAYS-----------YSYYLKLAKKQKETQSG-AQREMGPVASADKPTTKLSASRNDEGFSSSSQDVNGFT-------------------------------------DGSRGELSQPTLTIQTHPYRTCDPVEMSYPRDQFQPAIRVADLLQHITQMKRGQGYGFKEEYEALPEGQTASWDTAKEDENRNKNRYGNIISY---DHSRVRLLVLDGD--PHSDYINANYIDGYHRPRHYIATQGPMQETVKDFWRMIWQ---ENSASIVMVTNLVEVGR--------------------VKCVRYWPDDTEVYGDIKVTLIETEPLAEYVIRTFTVQKKGYHEIRELRLFHFTSWPDHGVPCYATGLLGFVRQVKFLNPPEAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLYYNISRLDPQTNSSQIKDEFQTLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFLISVDGESSNYINAALMDSHKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNEMDTAQFCMQYWPEKTSGCYGPIQVEFVSADIDEDIIHRIFRICNMARPQDGYRIVQHLQYIGWPAYRDTPPSKRSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIVKTLRNNKSNMVETLEQYKFVYEVALEYLSSF----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q0Y4-1", "uniprot_id": "A0A8M9Q0Y4_DANRE", "id": "A0A8M9Q0Y4-1", "name": "protein-tyrosine-phosphatase", "aln": "MDQRNYFALLLLVLHVQLTFGEFFPGS--------CSFEEHYSNCGYSVALGTNGFAWEQVNTWERPSMDAAVPTGSFMMVNASGRASGQKAHLLLPTLKENDTHCIDFHYSLSSRDGTSPGTLNVYIKVDGGPQGNPIWNASTPVTEGWVKAELAISTFWPNSYQVIFEAVSVQGHPGFIAVDEIHVLAHPCRKTPHFLRLQNVEVNVGQNATFQCIAGGKWSQHDKLWLQQWNGKDTSLMVTRVVNHRRFSATVSVTDTSQRSTSRYRCVIRSDGGSGVSNYAELSVKAPPTPIAPPELLAVGATYLWIKPNANSIIGDGPIILKEVEYRTTTGNWAETHVVDAPTYKLWHLDPDVEYEIKVLLTRPGEGGTGPPGPPLITRTKCADPVNGPQNVNVVDIRARQLTLQWETFGYAVTRCHSFNLTVQYQYVFNQQVYATEDLIPTSSHYTLRGLRPFVTVRLRLVLANPEGSKESEEIVKQTEEDVPGPIPMESIQTGPYEEKIFMQWKAPNETNGVITLYEIAYKALSSLDPTADLTTQRGRVFKLQNETHHLFVGLYPGTTYFFTLKASTNKGFGPPVTTRITTKIAAPSMPEYETDSPLNETDTTITVLLKPAQSRGAPVSSYQVVVQEERKQKVRRATDVLECFPVPVSFRNASILDSPHYFAAELPPVSLAVVQPFTIGDNKTYNGYWNAPLSPAKSYSIYFQALSKANGETKINCVRLATKVVIGRGQNTTPYILVIPSEGASTQNSNDIEPEKQVDSTVKMAGVIAGILMFVIILLGLLLTFKRREIHTWRTLSVGRNAYSYSYYLKLAKKQKETASSSTQREMGPVGTADKSTGKVSTLHKDDPFSTSNQDLNGFSSSSPCSFSIQGKAIQSKTLLNSYYSVSKEPVPATASIDGSHSEMSQPSMTIQTYPYGGCESVEMSYQAGQFQPAIRVADLLQHITQMKCGQGYGFKEEYEGLAEGQTAPWETAKKEENRNKNRYGNIIAYPTDDHTRVRLQPLEGD--PHSDYINANYIDGYHRPRHYIATQGPMQETVRDFWRMIWQ---ENSASIVMVTNLVEVGR--------------------VKCVRYWPDETEVYGDIKVTLIETEPLAEYVIRTFTVQKKGHHEIREIRQFHFTSWPDHGVPCYATGLLGFIRQVKFLNPPDAGPIVVHCSAGAGRTGCFIAVDIMLDMAESEGVVDIFNCIRELRSQRVNMVQTEEQYVFVHDAILEACLCGNTAIPVCEFRAIYYNISRLDPQTNSSQVKDEFQTLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLAVDRCLPFLISVDGESSNYINAALMDSHKQPAAFIVTQHPLPNTMADFWRLVFDYNCSTIVMLNEMDAAQLCMQYWPEKGSCCYGPIQVEFISADIDEDIINRIFRICNMARPQDGYRLVQHFQFIGWPAYRDTPLSKRSILQLVRRLAKWQEQYDGGDGRTVVHCLTGGGRSGTFCAICSICEMIQQQNIVDVFHTVKTLRNNKANMVETMEQYKFCYEVALESLNGF----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P25044-1", "uniprot_id": "PTP1_YEAST", "id": "P25044-1", "name": "Tyrosine-protein phosphatase 1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAAAPWYIRQRDTDLLGKFKFIQNQEDGRLREATNGTVN-SRWSLGVSIEPRNDARNRYVNIMPY---ERNRVHLKTLSGNDYINASYVKVNVPGQSIEPGYYIATQGPTRKTWDQFWQMCYHNCPLDNIVIVMVTPLVEYNR--------------------EKCYQYWP---------------------------------------------------------------------------------------RGGVDDTVRIASKWESPGGANDMTQFPSDLKIEFVNVHKVKDYYTVTD-----------------------IKLTPTDPLVGPVKTVHHFY------------------FDLWKDMNKPEEVVPIMELCAHSHSLNSRG-------------------------------------------------------------------------------------NPIIVHCSAGVGRTG-------TFIALDHLMHDTLDFKNITERSRHSDRATEEYTR--------------------------DLIEQ--------IVLQLRSQRMKMVQTKDQFLFIYHAAKYLNSLSVNQ-------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P40048-1", "uniprot_id": "PTP3_YEAST", "id": "P40048-1", "name": "Tyrosine-protein phosphatase 3", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKDSVDCPSILPTDRTSVLSETSTLVGSSSHVYSRHAPMNSYHNSMNSNIYHSPKASSPLVSYKTSSPVLLKRATAPVLPSFKPKEQRYNKPQGCSLITAVELGKIIETLPDEKVLLLDVRPFTEHAKSIITNSIHVCLPSTLLRRKNFTFSKLLDNLTPSEQSVLKSKLAIDNLRIIIYDSTANQTESSVSLPCYGIASKLIEFDTNVKKTVSILMCGFPQFKILFPDHINTNTFNSDCISSAEPKSPKTN---------------------------------LMNSLHNTAPHMTATTPLSSPQMNLKLKVPDDSRSDHSNFSSSPSPRNVLSDSPMSSSSPISALFKFQLPAP---------QTNINQMFKFSQNEEIMGLETYLSAVNIKEEHERWYNNDSAKKSLQNFQFPKNQNSLEKDTNKDKLGFQIRYENLSKNYEKEVIDSVIPEWFQHLMSIPKIELVSQFQKLDFLE-----------------------------------------------------------------------------------------------------KRRLNHSVSFRKKENSFILEKPSSYPEQLTSTSSSTIMPPKFPDVNKVQ-----------------------------------------------------KRSHSQPIFTQYSKYKSMLSLESDSDSESDDVIISSGVELGAKNRYKDIFPYEHSRVILKKGLQSSKGIKHSHSTSDGGILDNYINANYLSLPRFSVEQNSSFQTTTTTTRRVRYIATQAPMPSTVHDFYTCILN----NGVPLVLSLTNDFENG-------------------IEKCYRYWQE----------------------------------------------------------------------------------GNYNGIHVKLLEKKILKMPSTTSMRKNTMGTQNSSLYSAGVQGNSSNYSTDND----------------------NDNDNNNNNNNNSNIAVTAAACDDDDDDDDDAILIRKILLTYHDQEKPYELLQIQVKNWPDLGTLLNPISILQAINVKNHIIDTLFARNYYQ---------------------------------------------------------NDQLPTILVHCSAGCGRTG-------TLCTIDSILSNFEMFEMLQKEFVKLKYPAKLFDPISWTINIFRKQRISMVQNINQFIFIYDCLLFYFRLRLDDITERTDGDGSNKDNISLSALIEQIEKLEILQTFVDDKLKELPQ", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* . :. :: : . .. :: : . . :. *. . . : . *****.* .* :*: : :. :*: . ** :** . . . . : ..: .. * . . : . : : :* ::. ::: : . . *: *. . : * . : : : : : : : . .: : : . : . ", "identical_positions": 20, "similar_positions": 79, "identity": "1.29%" }, { "cls_id": "homologset.agr.MGI:1321159", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P63330-1", "uniprot_id": "PP2AA_MOUSE", "id": "P63330-1", "name": "Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform", "aln": "----------------------------------------------------------MDEKLFTK----------ELDQWIEQLNECKQLSESQVKSLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPRRGEPHVTRRTPDYFL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P63331-1", "uniprot_id": "PP2AA_RAT", "id": "P63331-1", "name": "Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform", "aln": "----------------------------------------------------------MDEKLFTK----------ELDQWIEQLNECKQLSESQVKSLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPRRGEPHVTRRTPDYFL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A0G2JYA4-1", "uniprot_id": "A0A0G2JYA4_RAT", "id": "A0A0G2JYA4-1", "name": "Serine/threonine-protein phosphatase", "aln": "----------------------------------------------------------MDEKLFTK----------ELDQWIEQLNECKQLSESQVKSLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPTIDTLDHIGALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPRRGEPHVTRRTPDYFL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P67775-1", "uniprot_id": "PP2AA_HUMAN", "id": "P67775-1", "name": "Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform", "aln": "----------------------------------------------------------MDEKVFTK----------ELDQWIEQLNECKQLSESQVKSLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPRRGEPHVTRRTPDYFL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PFZ9-1", "uniprot_id": "A0A8M1PFZ9_DANRE", "id": "A0A8M1PFZ9-1", "name": "Serine/threonine-protein phosphatase", "aln": "----------------------------------------------------------MEEKAFAK----------ELDQWIEQLNECKQLSETQVKTLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVSLLVALKVRYRERVTILRGNHESRQITQVYGFYDECLRKYGNANVWKFFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPRRGEPHVTRRTPDYFL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P23696-1", "uniprot_id": "PP2A_DROME", "id": "P23696-1", "name": "Serine/threonine-protein phosphatase PP2A", "aln": "----------------------------------------------------------MEDKATTK----------DLDQWIEQLNECNQLTETQVRTLCDKAKEILSKESNVQEVKCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDSLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNNTNGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAALMELDDSLKFSFLQFDPAPRRGEPHVTRRTPDYFL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P23594-1", "uniprot_id": "PP2A1_YEAST", "id": "P23594-1", "name": "Serine/threonine-protein phosphatase PP2A-1 catalytic subunit", "aln": "MDTDLDVPMQDAVTEQLTPTVSEDMDLNN--------NSSDNNAEEFSVDDLKPGSSGIADHKSSKPLELNNTNINQLDQWIEHLSKCEPLSEDDVARLCKMAVDVLQFEENVKPINVPVTICGDVHGQFHDLLELFKIGGPCPDTNYLFMGDYVDRGYYSVETVSYLVAMKVRYPHRITILRGNHESRQITQVYGFYDECLRKYGSANVWKMFTDLFDYFPITALVDNKIFCLHGGLSPMIETIDQVRELNRIQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGFTFGQDVSEQFNHTNDLSLIARAHQLVMEGYAWSHQQNVVTIFSAPNYCYRCGNQAAIMEVDENHNRQFLQYDPSVRPGEPSVSRKTPDYFL", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P23595-1", "uniprot_id": "PP2A2_YEAST", "id": "P23595-1", "name": "Serine/threonine-protein phosphatase PP2A-2 catalytic subunit", "aln": "MDMEIDDPMHGSDEDQLSPTLDEDMNSDDGKNNTKARSNDEDTDEELEDFNFKPGSSGIADHKSSKPLKLTNTNINQLDQWIEHLSKCEPLSEDDVARLCKMAVDVLQFEENVKPINVPVTICGDVHGQFHDLLELFKIGGPCPDTNYLFMGDYVDRGYYSVETVSYLVAMKVRYPHRITILRGNHESRQITQVYGFYDECLRKYGSANVWKMFTDLFDYFPVTALVDNKIFCLHGGLSPMIETIDQVRDLNRIQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGFTFGQDISEQFNHTNDLSLIARAHQLVMEGYSWSHQQNVVTIFSAPNYCYRCGNQAAIMEVDENHNRQFLQYDPSVRPGEPTVTRKTPDYFL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: :* :******:*.:*: *:* :* **. * ::* *.**: :. ***:***********:***:*** .**********************: ***:**** .*:***************************.***** *******:*:*****.:********** *:::*:: *:*:*******************************:*****:** **::*.*:*::********** *.*::********************:**:*:. : .***:**: * *** *:*:******", "identical_positions": 223, "similar_positions": 59, "identity": "59.15%" }, { "cls_id": "homologset.agr.MGI:1321161", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62714-1", "uniprot_id": "PP2AB_HUMAN", "id": "P62714-1", "name": "Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform", "aln": "----------------------------------------------------------MDDKAFTK----------ELDQWVEQLNECKQLNENQVRTLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYPERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPRRGEPHVTRRTPDYFL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62716-1", "uniprot_id": "PP2AB_RAT", "id": "P62716-1", "name": "Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform", "aln": "----------------------------------------------------------MDDKAFTK----------ELDQWVEQLNECKQLNENQVRTLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYPERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPRRGEPHVTRRTPDYFL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P62715-1", "uniprot_id": "PP2AB_MOUSE", "id": "P62715-1", "name": "Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform", "aln": "----------------------------------------------------------MDDKAFTK----------ELDQWVEQLNECKQLNENQVRTLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYPERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPRRGEPHVTRRTPDYFL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P23696-1", "uniprot_id": "PP2A_DROME", "id": "P23696-1", "name": "Serine/threonine-protein phosphatase PP2A", "aln": "----------------------------------------------------------MEDKATTK----------DLDQWIEQLNECNQLTETQVRTLCDKAKEILSKESNVQEVKCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDSLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNNTNGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAALMELDDSLKFSFLQFDPAPRRGEPHVTRRTPDYFL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P23594-1", "uniprot_id": "PP2A1_YEAST", "id": "P23594-1", "name": "Serine/threonine-protein phosphatase PP2A-1 catalytic subunit", "aln": "MDTDLDVPMQDAVTEQLTPTVSEDMDLNN--------NSSDNNAEEFSVDDLKPGSSGIADHKSSKPLELNNTNINQLDQWIEHLSKCEPLSEDDVARLCKMAVDVLQFEENVKPINVPVTICGDVHGQFHDLLELFKIGGPCPDTNYLFMGDYVDRGYYSVETVSYLVAMKVRYPHRITILRGNHESRQITQVYGFYDECLRKYGSANVWKMFTDLFDYFPITALVDNKIFCLHGGLSPMIETIDQVRELNRIQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGFTFGQDVSEQFNHTNDLSLIARAHQLVMEGYAWSHQQNVVTIFSAPNYCYRCGNQAAIMEVDENHNRQFLQYDPSVRPGEPSVSRKTPDYFL", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P23595-1", "uniprot_id": "PP2A2_YEAST", "id": "P23595-1", "name": "Serine/threonine-protein phosphatase PP2A-2 catalytic subunit", "aln": "MDMEIDDPMHGSDEDQLSPTLDEDMNSDDGKNNTKARSNDEDTDEELEDFNFKPGSSGIADHKSSKPLKLTNTNINQLDQWIEHLSKCEPLSEDDVARLCKMAVDVLQFEENVKPINVPVTICGDVHGQFHDLLELFKIGGPCPDTNYLFMGDYVDRGYYSVETVSYLVAMKVRYPHRITILRGNHESRQITQVYGFYDECLRKYGSANVWKMFTDLFDYFPVTALVDNKIFCLHGGLSPMIETIDQVRDLNRIQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGFTFGQDISEQFNHTNDLSLIARAHQLVMEGYSWSHQQNVVTIFSAPNYCYRCGNQAAIMEVDENHNRQFLQYDPSVRPGEPTVTRKTPDYFL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *: :* :****:*:*.:*: *.* :* **. * ::* *.**: :. ***:***********:***:*** .**********************: ***:**** .*****************************.***** *******:*:*****.:********** *:::*::* *:*:*******************************:*****:** **::*.*:*::********** *.*::********************:**:*:. : .***:**: * *** *:*:******", "identical_positions": 225, "similar_positions": 58, "identity": "59.68%" }, { "cls_id": "homologset.agr.MGI:1321385", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6P6S9-1", "uniprot_id": "ENTP5_RAT", "id": "Q6P6S9-1", "name": "Ectonucleoside triphosphate diphosphohydrolase 5", "aln": "----------------------------------------MATSWASVF-LLIIAYVGGTVFYREQQTWFEGVFLSSMCPVN-----------------------------------------------------VSAGTFYGIMFDAGSTGTRIHVYTFVQRTSGQLPFLEGEIFDSVKPGLSAFVDQPKQGAETVQELLEVAKDSIPRSHWKRTPVVLKATAGLRLLPEQKAQTLLLEVEEIFKNSP--FLVPDDSVSIMDGSYEGILAWVTVNFLTG--QLHGRGQETVGTLDLGGASTQITFLPQLEKTLEQTPKGYLASFEMFNSTFKLYTHSYLGFGLKAAR-----------LATLGALEAEGTDGHTFRSACL-PRWLEAEWIFGG-------VKYQYGGNQEGE---------MGFEPCYAEVRRVVQGKLHQPEE--IRGSS-FYAFSYYYDRAAETHL--------IDYEKGGVLKVEDFERKAREVCDNLESFSSGSPFLCMDLSYITALLKDGFGFEDGTLLQLTKKVNNIETGWALGATFHLLQSLGITS-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WUZ9-1", "uniprot_id": "ENTP5_MOUSE", "id": "Q9WUZ9-1", "name": "Ectonucleoside triphosphate diphosphohydrolase 5", "aln": "----------------------------------------MATSWGAVF-MLIIACVGSTVFYREQQTWFEGVFLSSMCPIN-----------------------------------------------------VSAGTFYGIMFDAGSTGTRIHVYTFVQKTAGQLPFLEGEIFDSVKPGLSAFVDQPKQGAETVQELLEVAKDSIPRSHWERTPVVLKATAGLRLLPEQKAQALLLEVEEIFKNSP--FLVPDGSVSIMDGSYEGILAWVTVNFLTG--QLHGRGQETVGTLDLGGASTQITFLPQFEKTLEQTPRGYLTSFEMFNSTFKLYTHSYLGFGLKAAR-----------LATLGALEAKGTDGHTFRSACL-PRWLEAEWIFGG-------VKYQYGGNQEGE---------MGFEPCYAEVLRVVQGKLHQPEE--VRGSA-FYAFSYYYDRAADTHL--------IDYEKGGVLKVEDFERKAREVCDNLGSFSSGSPFLCMDLTYITALLKDGFGFADGTLLQLTKKVNNIETGWALGATFHLLQSLGITS-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75356-1", "uniprot_id": "ENTP5_HUMAN", "id": "O75356-1", "name": "Nucleoside diphosphate phosphatase ENTPD5", "aln": "----------------------------------------MATSWGTVFFMLVVSCVCSAVSHRNQQTWFEGIFLSSMCPIN-----------------------------------------------------VSASTLYGIMFDAGSTGTRIHVYTFVQKMPGQLPILEGEVFDSVKPGLSAFVDQPKQGAETVQGLLEVAKDSIPRSHWKKTPVVLKATAGLRLLPEHKAKALLFEVKEIFRKSP--FLVPKGSVSIMDGSDEGILAWVTVNFLTG--QLHGHRQETVGTLDLGGASTQITFLPQFEKTLEQTPRGYLTSFEMFNSTYKLYTHSYLGFGLKAAR-----------LATLGALETEGTDGHTFRSACL-PRWLEAEWIFGG-------VKYQYGGNQEGE---------VGFEPCYAEVLRVVRGKLHQPEE--VQRGS-FYAFSYYYDRAVDTDM--------IDYEKGGILKVEDFERKAREVCDNLENFTSGSPFLCMDLSYITALLKDGFGFADSTVLQLTKKVNNIETGWALGATFHLLQSLGISH-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F8A7-1", "uniprot_id": "E7F8A7_DANRE", "id": "E7F8A7-1", "name": "nucleoside diphosphate phosphatase", "aln": "-------------------------------MSQQMLHLTLVSMWLFAGYFLAEATYYNHHMYNRYRAINHNANMDNQLPPEEPVVMEPVAP----------------------------------------RQVNFSRVFYGIMFDAGSSGTRIHIYKFIQKDPVELPVLDNEMYHAVKPGLSAYADMPEKGGESIVQLLKVAKKTIPKEQWIQTPVVLKATAGLRLLPEEKAKALLNEVKEVFDDSP--FFVPNNSVTIMNGINEGVLAWVTVNFLTG--HLYSKTKRTVGILDLGGGSTQITFLPRLKKTVQSAPSDYIAKINMFNSTYELYTHSYLGNGVFASR-----------LATLGALGADGLEWKVFRSSCL-PKKFSEEWSFGG-------LTYKVSGTPDGY---------AGYKLCYQEVLQVVKGIVHQPFE--VKGSSIFYAFSYYYDRAVESGL--------IDGSRGGTVEVRDFKKKAKEVCNKMTKYRPISPYLCMDMTYITCLLKDGFGFKDSTVLQLAKKVNNVETSWALGAIFDHFHNFSIQ------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32T969-1", "uniprot_id": "A0AB32T969_DANRE", "id": "A0AB32T969-1", "name": "nucleoside diphosphate phosphatase", "aln": "----------------------------MNLLYPAPLSAALADLGQMVMKMMMFWLLPVWTLLLLSSSASSSSPPSSSAAADFSVRFGHTLPSLS-------------------------------------RPANSTQIFYGIMFDAGSTGTRIHVYTFIQREPDGLPVLDNEMFHSMKPGLSAYADMPEIAGHTVRQLLRVAKKTVPPLEWKRTPLVFRATAGLRLLPAAKAHALLEEVQDVFDESP--FYVPPDSVRIMNGTSEGILAWVTVNFLTG--RLERNTEKTVGILDLGGGSTQITFLPKSKKTIEAAPPDYISRFQMFNCSYQLYTHSYLGNGIKAAR-----------LSALGALNADGLEKKLFRSSCL-SRSHTAEFSFGG-------VSYHVSGDISGV---------RGYKACYQELVKVVKGIIKQPLE--LRDSSSFYAFSYYYDHAVEAGL--------IDEQRGGAVKVRDFRKTARQVCNRPARHTQLNQFLCMDLTYITCLLKDGFGFKESTVLQLTKKVRNVETSWALGAAIDHFQKSRIH------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9PBV2-1", "uniprot_id": "M9PBV2_DROME", "id": "M9PBV2-1", "name": "nucleoside diphosphate phosphatase", "aln": "MTNTDVRKRKLATDEKPPRRKSSGSPNASSGGNRGPSGLKISFLCLIISVILLLFVFGVYHLYYVKDEVPKVVLTKTSDFPTVTVPYAHVEPHFAPPVRRVITKKPIANKPTTDNDAGFVSENASPYLARLASKFGYSKVQYAAIIDAGSTGSRVLAYKFNRSFIDNKLVLYEELFKERKPGLSSFADNPAEGAHSIKLLLDEARAFIPKEHWSSTPLVLKATAGLRLLPASKAENILNAVRDLFAKSE--FSVDMDAVEIMDGTDEGIFSWFTVNFLLG--RLSKTN--QAAALDLGGGSTQVTFSP-TDPDQVPVYDKYMHEVVTSSKKINVFTHSYLGLGLMAAR-----------HAVFTHGYKK--EDTVLESVCVNPIIANRTWTYGN-------VQYKVSGKENGKSS--AEQPIVDFDACLELVKSKVMPLVKPKPF--TLKQHAVAAFSYYFERAIESGL--------VDPLAGGETTVEAYRKKAQEICAIPNDEQ---PFMCFDLTFISTLLREGFGLNDGKKIKLYKKIDGHEISWALGCAYNVLTSDEKFSNS---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32621-1", "uniprot_id": "GDA1_YEAST", "id": "P32621-1", "name": "Guanosine-diphosphatase", "aln": "-------------------------MAPIFRNYRFAIGAFAVIMLILLIKTSSIGPPSIARTVTPNASIPKTPEDISILPVNDEPGYLQDSKTEQN------------------------YPELADAVKSQTSQTCSEEHKYVIMIDAGSTGSRVHIYKFDVCTSP--PTLLDEKFDMLEPGLSSFDTDSVGAANSLDPLLKVAMNYVPIKARSCTPVAVKATAGLRLLGDAKSSKILSAVRDHLEKDYPFPVVEGDGVSIMGGDEEGVFAWITTNYLLGNIGANGPKLPTAAVFDLGGGSTQIVFEPTFPINEKMVDGEHKFDLKFGDENYTLYQFSHLGYGLKEGRNKVNSVLVENALKDGKILKGDNTKTHQLSSPCLPPKVNATNEKVTLESKETYTIDFIGPDEPSGAQCRFLTDEILNKDAQCQSPPCSFNGVHQPSLVRTFKESNDIYIFSYFYDRTRPLGMPLSFTLNELNDLARIVCKGEETWNSVFSGIAGSLDELESDSHFCLDLSFQVSLLHTGYDIPLQRELRTGKKIANKEIGWCLGASLPLLKADNWKCKIQSA", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * ::****:*:*: *.* * * :. :****:: . ...:: ** * :* **:..:******** *: :* *.: : .. * ..* **.* **:::*.*.*:* * .. :****.***:.* * . : . . . :: .*:** *: .* . . : * *: . : : . .* . . . : . ***::::: : :: . ... . .:*:*::: **: *:.: :: **: . * .*.**. : ", "identical_positions": 75, "similar_positions": 101, "identity": "13.18%" }, { "cls_id": "homologset.agr.MGI:1321386", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BFW6-1", "uniprot_id": "ENTP3_MOUSE", "id": "Q8BFW6-1", "name": "Ectonucleoside triphosphate diphosphohydrolase 3", "aln": "---MFTVMTRQPCEQAG-FRALSRTPAIVTLVVLLVSIVVLVTLTLIQIRHPQVLPPGLKYGVVLDAGSSRTTVYVYQWPAEKENNTGVVSQTFRCSVKGSGISSYENNPQDAPKAFEDCILKVKEQVPEHLHGSTRIYLGATAGMRLLRLQNETAAREVLESIQSYFKSQPFDFRGAQIISGQEEGVYGWITANYIMGNFLEKNLWHMWVHPHGVDTTGALDLGGASTQISFVAGEKMEPNASDTVQVSLYGYTYTLYTHSFQCYGQNEAEKKFLAMLLQSPSTEANISNPCYPQGYSTAFTLGHVFGSLCTEKQRPESYNSSKSVTFMGTGDPRLCREKVASVFDFNACQEQDACSFDGIYQPKVQGPFVAFAGFYYTASALNLSGSFSLTSFNDSSWDFCRHTWSELPALLSRFDETYARSYCFSAHYIYHLLVNGYKFTEETWPQIRFEKEVGNSSIAWSLGYMLSLTNQIPAGSPLIHLPIQPPVFMGVLAFFTAIALLCLAFLLYLCSSFRTKERSENAFDQAVDSD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K5S7-1", "uniprot_id": "A0A0G2K5S7_RAT", "id": "A0A0G2K5S7-1", "name": "apyrase", "aln": "RTTVLTSFTEIKEKIVSCFRALSRTPAIVTLVVLLVSIVVLVTLTLIQIHHPQVLSPGLKYGIVLDAGSSRTTVYVYQWPAEKENNTGVVSQTFRCSVKGSGISSYENNPQDAPKAFEDCMLKVKEQVPKHLHESTRVYLGATAGMRLLRLQNETAAHEVLESIQSYFKSQPFDFRGAQIISGQEEGVYGWITANYIMGNFLEKNLWHMWVHPHGVDTTGALDLGGASTQISFVSEEKMEPNASDTVQVSLYGYTYTLYTHSFQCYGRNEAEKKFLAMLLQSPSTDANISNPCYPHGYSTTFTMGHVFGSLCTEKQRPKSYNPSDTITFTGTGDPQLCREKVASVFDFSACQEQDACSFDGIYQPKVQGPFVAFAGFYYTASALNLSGSFSLTSFNDSSWDFCRHTWSELPSLLPRFDETYARSYCFSAHYIYHLLINGYKFTEATWPQIRFEKEVGNSSIAWSLGYMLSLTNQIPAGSPLIQLPIQPPVFMGVLAFFTAIALLCLAFLFYLCSAFRTKERSENAFDQAVDSD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75355-1", "uniprot_id": "ENTP3_HUMAN", "id": "O75355-1", "name": "Ectonucleoside triphosphate diphosphohydrolase 3", "aln": "---MFTVLTRQPCEQAG-LKALYRTPTIIALVVLLVSIVVLVSITVIQIHKQEVLPPGLKYGIVLDAGSSRTTVYVYQWPAEKENNTGVVSQTFKCSVKGSGISSYGNNPQDVPRAFEECMQKVKGQVPSHLHGSTPIHLGATAGMRLLRLQNETAANEVLESIQSYFKSQPFDFRGAQIISGQEEGVYGWITANYLMGNFLEKNLWHMWVHPHGVETTGALDLGGASTQISFVAGEKMDLNTSDIMQVSLYGYVYTLYTHSFQCYGRNEAEKKFLAMLLQNSPTKNHLTNPCYPRDYSISFTMGHVFDSLCTVDQRPESYNPNDVITFEGTGDPSLCKEKVASIFDFKACHDQETCSFDGVYQPKIKGPFVAFAGFYYTASALNLSGSFSLDTFNSSTWNFCSQNWSQLPLLLPKFDEVYARSYCFSANYIYHLFVNGYKFTEETWPQIHFEKEVGNSSIAWSLGYMLSLTNQIPAESPLIRLPIEPPVFVGTLAFFTAAALLCLAFLAYLCSATRRKRHSEHAFDHAVDSD", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::* :*. : .. ::** ***:*::************::*:***:: :**.******:*******************************:*********** *****.*:***:*: *** ***.*** ** ::******************.**************************************:*******************:*****************: ***: *:** :*******.************:*************...*. :::*****:.** :**:****.**** .***:***... :** ***** **:*****:***.**::*::*****:****::************************ :**.*:*:** :.**:** **.:***.*********:*****::******* *****:************************** ****:***:****:*.****** ******** ****: * *.:**:***:*****", "identical_positions": 411, "similar_positions": 88, "identity": "77.11%" }, { "cls_id": "homologset.agr.MGI:1321389", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P63024-1", "uniprot_id": "VAMP3_MOUSE", "id": "P63024-1", "name": "Vesicle-associated membrane protein 3", "aln": "MSTGVPSGSSAATG-----------------------------SNRRLQQTQNQVDEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFETSAAKLKRKYWWKNCKMWAIG--ISVLVIIVIIIIVWCVS------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P63025-1", "uniprot_id": "VAMP3_RAT", "id": "P63025-1", "name": "Vesicle-associated membrane protein 3", "aln": "MSTGVPSGSSAATG-----------------------------SNRRLQQTQNQVDEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFETSAAKLKRKYWWKNCKMWAIG--ISVLVIIVIIIIVWCVS------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q15836-1", "uniprot_id": "VAMP3_HUMAN", "id": "Q15836-1", "name": "Vesicle-associated membrane protein 3", "aln": "MST----GPTAATG-----------------------------SNRRLQQTQNQVDEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFETSAAKLKRKYWWKNCKMWAIG--ITVLVIFIIIIIVWVVSS-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P18489-1", "uniprot_id": "SYB_DROME", "id": "P18489-1", "name": "Synaptobrevin", "aln": "MENNEAPSPSGSNNNDFPILPPPPNANDNYNQFGDHQIRNNNAAQKKLQQTQAKVDEVVGIMRVNVEKVLERDQKLSELGERADQLEQGASQFEQQAGKLKRKQWWANMKMMIILGVIAVVLLIIVLVSVWPSSSDSGSGGGNKAITQAPPH", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P31109-1", "uniprot_id": "SNC1_YEAST", "id": "P31109-1", "name": "Synaptobrevin homolog 1", "aln": "MSSSTPFDPYALSEHD-------------------EERPQNVQSKSRTAELQAEIDDTVGIMRDNINKVAERGERLTSIEDKADNLAVSAQGFKRGANRVRKAMWYKDLKMKMCLALVIIILLVVIIVPIAVHFSR----------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.. .. . . :: : : * ::*:.*.*** *::** **.::*:.: ::** * .*. *: * :::: *: : ** : ::::.:::: : ", "identical_positions": 22, "similar_positions": 45, "identity": "14.47%" }, { "cls_id": "homologset.agr.MGI:1321390", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9R1E6-1", "uniprot_id": "ENPP2_MOUSE", "id": "Q9R1E6-1", "name": "Autotaxin", "aln": "--MARQGCFGSYQVISLFTFAIGVNLCLGFTASRIKRAE-WDEGPPTVLSD-SPWTN----TSGSCKGRCFELQEVGPPDCRCDNLCKSYSSCCHDFDELCLKTARGWECTKDRCGEVRNEENACHCSEDCLSRGDCCTNYQVVCKGESHWVDDDCEEIRVPECPAGFVRPPLIIFSVDGFRASYMK-KGSKVMPNIEKLRSCG----THAPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPVFDATFHLRGREKFNHRWWGGQPLWITATKQGVRAGTFFWSVSIPHERRILTILQWLSLPDNERPSVYAFYSEQPDFSGHKYGPFGPEMTNPLREIDKTVGQLMDGLKQLKLHRCVNVIFVGDHGMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRPKIPNNLKYDPKAIIANLTCKKPDQHFKPYMKQHLPKRLHYANNRRIEDLHLLVERRWHVARKPLDVYKKPSGKCFFQGDHGFDNKVNSMQTVFVGYGPTFKYRTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLLRTNTFRPTLPEEVSRPNYPGIMYLQSDFDLGCTCDDKVEPKNKLEELNKR----LHTKGSTE-------------------------ERHLLYGRPAVLYRTSYDILYHTDFESGYSEIFLMPLWTSYTISKQAEVSSIPEHLTNCVRPDVRVSPGFSQNCLAYKNDKQMSYGFLFPPYLSSSPEAKYDAFLVTNMVPMYPAFKRVWTYFQRVLVKKYASERNGVNVISGPIFDYNYNGLRDIEDEIKQYVEGSSIPVPTHYYSIITSCLDFTQPADKCDGPLSVSSFILPHRPDNDESCNSSEDESKWVEELMKMHTARVRDIEHLTGLDFYRKTSRSYSEILTLKTYLHTYESEI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q64610-1", "uniprot_id": "ENPP2_RAT", "id": "Q64610-1", "name": "Autotaxin", "aln": "--MARQGCLGSFQVISLFTFAISVNICLGFTASRIKRAE-WDEGPPTVLSD-SPWTN----TSGSCKGRCFELQEVGPPDCRCDNLCKSYSSCCHDFDELCLKTARGWECTKDRCGEVRNEENACHCSEDCLSRGDCCTNYQVVCKGESHWVDDDCEEIKVPECPAGFVRPPLIIFSVDGFRASYMK-KGSKVMPNIEKLRSCG----THAPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPVFDASFHLRGREKFNHRWWGGQPLWITATKQGVRAGTFFWSVSIPHERRILTILQWLSLPDNERPSVYAFYSEQPDFSGHKYGPFGPEMTNPLREIDKTVGQLMDGLKQLRLHRCVNVIFVGDHGMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRAKSINNSKYDPKTIIANLTCKKPDQHFKPYMKQHLPKRLHYANNRRIEDIHLLVDRRWHVARKPLDVYKKPSGKCFFQGDHGFDNKVNSMQTVFVGYGPTFKYRTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLLRTNTFRPTMPDEVSRPNYPGIMYLQSEFDLGCTCDDKVEPKNKLEELNKR----LHTKGSTEAETGKFRGSKHENKKNLNGSVEPRKERHLLYGRPAVLYRTSYDILYHTDFESGYSEIFLMPLWTSYTISKQAEVSSIPEHLTNCVRPDVRVSPGFSQNCLAYKNDKQMSYGFLFPPYLSSSPEAKYDAFLVTNMVPMYPAFKRVWAYFQRVLVKKYASERNGVNVISGPIFDYNYDGLRDTEDEIKQYVEGSSIPVPTHYYSIITSCLDFTQPADKCDGPLSVSSFILPHRPDNDESCNSSEDESKWVEELMKMHTARVRDIEHLTGLDFYRKTSRSYSEILTLKTYLHTYESEI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q13822-1", "uniprot_id": "ENPP2_HUMAN", "id": "Q13822-1", "name": "Autotaxin", "aln": "--MARRSSFQSCQIISLFTFAVGVNICLGFTAHRIKRAEGWEEGPPTVLSD-SPWTN----ISGSCKGRCFELQEAGPPDCRCDNLCKSYTSCCHDFDELCLKTARGWECTKDRCGEVRNEENACHCSEDCLARGDCCTNYQVVCKGESHWVDDDCEEIKAAECPAGFVRPPLIIFSVDGFRASYMK-KGSKVMPNIEKLRSCG----THSPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPVFDATFHLRGREKFNHRWWGGQPLWITATKQGVKAGTFFWSVVIPHERRILTILQWLTLPDHERPSVYAFYSEQPDFSGHKYGPFGPEMTNPLREIDKIVGQLMDGLKQLKLHRCVNVIFVGDHGMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRSKFSNNAKYDPKAIIANLTCKKPDQHFKPYLKQHLPKRLHYANNRRIEDIHLLVERRWHVARKPLDVYKKPSGKCFFQGDHGFDNKVNSMQTVFVGYGSTFKYKTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLLRTNTFRPTMPEEVTRPNYPGIMYLQSDFDLGCTCDDKVEPKNKLDELNKR----LHTKGSTE-------------------------ERHLLYGRPAVLYRTRYDILYHTDFESGYSEIFLMPLWTSYTVSKQAEVSSVPDHLTSCVRPDVRVSPSFSQNCLAYKNDKQMSYGFLFPPYLSSSPEAKYDAFLVTNMVPMYPAFKRVWNYFQRVLVKKYASERNGVNVISGPIFDYDYDGLHDTEDKIKQYVEGSSIPVPTHYYSIITSCLDFTQPADKCDGPLSVSSFILPHRPDNEESCNSSEDESKWVEELMKMHTARVRDIEHLTSLDFFRKTSRSYPEILTLKTYLHTYESEI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58HF17-1", "uniprot_id": "A0AC58HF17_DANRE", "id": "A0AC58HF17-1", "name": "", "aln": "--MSNMDFIEVFSVLWLFS---RLTVCKTYVVRRSGKAASPDESLSKSFSD-HPFTS----LAGSCKKRCFELVEADPPNCRCDNLCKTYNMCCSDFDDHCLKTAGGFECSKERCGENRNEQHACHCSEDCMAKGDCCTNYRSLCKGDVPWLQEECEEIKNHECPAGFVRPPVIMLSVDGFRASYMK-RGGTVIPNIEKLRSCG----THAPYMRPMYPTKTYPNLYTITTGLYPESHGIVGNSIHDPSFDANFNFRGKEKLNHRWWGGQPIWITAMKQGVKAGSFFWPVAIPMERRVLTMLQWLHLPDAERPYLYAMHSEQLDSYGHKLGPHSTELNSALRDVDKVIGQLMNGLKQMKLHRCINIILVGDHGMEEAHCDKTEFLSSYMSNTEDLILIPGSLGRIRARNPNNSKFDAKAVVANLTCKKPDQHFKPYLKQHLPKRLHYANNDRIEEIHLMVERKWHIARKIMKTKRN-HEKCGFAGDHGYDNKINSMQTIFLGYGPAFKFKTKIPPFENIELYNIMCDLLGLKPAPNNGTHGSLNQLLRTPVYIPNMPEEVTKPNPAGPVIAIND-DLGCTCEDKVSNKLRSKSRGKRALKVTLVRGYNVESLWLCLLQNKVDELNQRLRQVIDDNKNLPYGRPAVMFRTKYCILHHTDYISGYSEALHMPLWTSYTVSKQVDFTPLTDALSNCIRPDSRVPTAYSQSCSNYRTEKQISYSFLYPPQLSSTQEARYDAVLITNTVPMYTAFKRVWSYFQKSLVKRYASEKNGVNVVTGPIFDYDYNGLRDSAETIKQFVSG-SVQIPTHYFVVVTSCLDYTQTVDSCVGPLSVFSFILPHRSDNEETCNSSEDESKWVEELMKTHTARLRDVELLTGLDFYRRTSRTYEEILALKTYLHTYESEI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P25353-1", "uniprot_id": "NPP1_YEAST", "id": "P25353-1", "name": "Ectonucleotide pyrophosphatase/phosphodiesterase 1", "aln": "MELQNDLESLDNELNDFSEDPFRDDFITDEDAVRSGWRSAWTRMKYWFYKNRLKWTNNPIVIGDAKDSRDGSNFRRGIPLYELDANGQPIDTELVDENELSFGTGF---HSKVPFKIIFRTLFGSLVFAIFLILMINIAKPHHSTRVLSHFGSPEFDPYVKYFNGTHEFFPLTIVISLDGFHPSLISKRNTPFLHDLYELKYDGGMNITSTPFMVPSFPTETFPNHWTLVTGQYPIHHGIVSNVFWDPDLNEEFHPGVLDPRIWNNNDTEPIWQTVQSAFDGD----------IPFKAATHMWPGSDVNYTKYNEEKLQPEHKNPIARERTPFYFDEFNAKEPLSQKLSKIIEYVDMSTLN------------------ERPQLILGYVPNVDAFGHKHG--------------YPSESEYYYEDFTETLGEVDTFLKQLVES-LQERNLTSFTN-------------------------LVIVSDHGMSDIVVPS--NVIIWEDLLDEKLRKDYVSHAYLEGPMMAISLKDSGNINEVYHNLKTSIDED---------------KYTVYVNGNFPKEWNFNDGKN------HHMAS-------------------------------------IWIVPEPGYAVMKKEQLKKVAKGDHKDKNEDNVFTIGSHGYD-NNAIDMRSVFIGMGPYFPQGYIEP---------FQNTEIYNLLCDICGVAEKDRNSNDGTGMLMNQLREPQSSEEVEIEDDFDYLVSKFGEFSTYNIIWGGYPEETEQDNVDNDNDDNDDGNTDEIAAMPSSSLTIKLEMTTSIPSATETLLGETSPSSRSSSSSSIQASATASTVGDWLQDIINDAKDLIDDIIDSIDDLVDSDT---------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P39997-1", "uniprot_id": "NPP2_YEAST", "id": "P39997-1", "name": "Ectonucleotide pyrophosphatase/phosphodiesterase 2", "aln": "-----------------------------------------------------------------------------MLLFE-----QPVDLEKNNEDDTNIK----------PFAISRHFLLKLLLCGIILIELLLYSK---CPKPIDNGPRTIANRSNTYFNGTHDFKTLTILISIDGFHPRLIDAKYTPFLYNLHNLRSPYDMNITTAPYMIPSFPTQTFPNHWSMVTGKYPIEHGIVSNIFWDNFTSSEFRPNNLDARIWSN-TADPIWQLLQTESQG------------EYKVATHMWPGSEVVYEDHGD----------VPRERMPFYFGKFNQWEKLQDKLAQIFRYIDMPQLK------------------DRPELVISYIPNVDSYGHSFG--------------YDLRD----KRLQKLIGEVDGFFLDLIEG-LQKRNLLKISN-------------------------VMIVSDHGMSNVNANDGEHVVVWERVFPADAMSAFISHLYNEGPMMMVCLKNPRDKQWICDLIEAQLEKAYGD--------EISRKFHVILKEDFDPSWKYFQYDNRKHRYDDRVGD-------------------------------------IWILADEYYAIVK--EMGDVPIG-----------IMGTHGYNFNNCSDMASIFIGMGPMFNNEVVPP---------FENIEVYNMLIKASALLGEEKTKKEKS--LLQ------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :. : :: : . : :: : : : . . *::*:***:. :. : .: :: :*: * :*:* * :**:*:** :::.** ** ****.* : * . *. : :*:* . : * : :: *. . . :.. :.::: :. *: ::.::: .*:.*.: * : . : ... :: : : *: * : : : .*** .: .: : : ..: . * : .. : :: : : : . : . : *:: : .* .: :. .: : . . :.. : . . . : : : ", "identical_positions": 42, "similar_positions": 137, "identity": "4.65%" }, { "cls_id": "homologset.agr.MGI:1321392", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97865-1", "uniprot_id": "PEX7_MOUSE", "id": "P97865-1", "name": "Peroxisomal targeting signal 2 receptor", "aln": "MS-----AARTLRVPGRHGYAAEFSPYLPGRLACAAAQHYGIAGCGTLLVLDQNE---------SGLQIFRSFDWNDGLFDVTWSENNEHVLVTCSGDGSLQLWD--TAKATG-------PLQVYKEHTQEVYSVDWSQTRGEQLVVSGSWDQTVKVWDPTVGNSLCTFRG---------------------------HESVIYSTIWSPHIPGCFASASGDQTLRIWDVKTTGVR--IVIPAHQ-TEILSCDWCKYNENLVVTGAVDCSLRGWDLRNVRQPVFELLG-------------------HTYAIRRVKFSPFHASVLASCSYDFTVRFWNFSKPDPLLETVEH---------------HTEFTCGLDLSLQS-PTQVADCSWDETIKIYDPVCLTVPG--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00628-1", "uniprot_id": "PEX7_HUMAN", "id": "O00628-1", "name": "Peroxisomal targeting signal 2 receptor", "aln": "MSAVCGGAARMLRTPGRHGYAAEFSPYLPGRLACATAQHYGIAGCGTLLILDPDE---------AGLRLFRSFDWNDGLFDVTWSENNEHVLITCSGDGSLQLWD--TAKAAG-------PLQVYKEHAQEVYSVDWSQTRGEQLVVSGSWDQTVKLWDPTVGKSLCTFRG---------------------------HESIIYSTIWSPHIPGCFASASGDQTLRIWDVKAAGVR--IVIPAHQ-AEILSCDWCKYNENLLVTGAVDCSLRGWDLRNVRQPVFELLG-------------------HTYAIRRVKFSPFHASVLASCSYDFTVRFWNFSKPDSLLETVEH---------------HTEFTCGLDFSLQS-PTQVADCSWDETIKIYDPACLTIPA--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VSN7-1", "uniprot_id": "Q9VSN7_DROME", "id": "Q9VSN7-1", "name": "Peroxin-7", "aln": "MQ------TQTHTTTDRHGYSLRFSPFEANYLLLATSQLYGLAGGGSLFLLEQNSNTNSSSTDGQSLGELCRLEWSDGLFDVAWCPYAADIAATASGDGSLQIWCGLDGESASNQLTPKQPLICLQEHKNEVYSLDWGEKWNYHTLLSGSWDCTLKLWDCNRQNSITTFVG---------------------------HNDLIYGAKFSPLIANLFASVSTDGHLNLWNSLDFAGKPLMSIEAHA-SEALCCDWSHFDRNVLVTGGSDGLIRGWDLRKMRTHVFELYS-------------------GEFAVRRLACSPHSAAVLASANYDFTTRIWNLERGESAQEVNAR---------------HTEFVCGLDWNPHR-THQLADCGWDSLANVYTPQCLSGDLVV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39108-1", "uniprot_id": "PEX7_YEAST", "id": "P39108-1", "name": "Peroxisomal targeting signal 2 receptor", "aln": "--------MLRYHMQGFSGYGVQYSPFFDNRLAVAAGSNFGLVGNGKLFILEIDRS--------GRIVEVNSFLTQDCLFDLAWNESHENQVLVAQGDGTLRLFDT-TFKEFP--------IAIFKEHEREVFSCNWNLVNR-QNFLSSSWDGSIKIWSPLRKQSLMTLTPRPLEITKMVDPLNAIILKKKSFTGISKNRNCVYQAQFSPHDQNLVLSCSGNSYASLFDIRLPSGKNQNNFLVHSGLEALTCDFNKYRPYVVATGGVDNAIRIWDIRMLNKNESATIKRTVPGQLHNSSCINEIPNAHGLAIRKVTWSPHHSNILMSASYDMTCRIWRDLSNDGAKETYKTNSTDATKGSIFNFTQHSEFVFGADWSLWGKPGYVASTAWDGNLFVWNGLG-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . **. .:**: . * *:.. :*:.* *.*::*: : : . : .* ***::* . ...***:*::: : : :** .**:* :*. : .:*.*** ::*:*. :*: *: :.. :* : :** . . * * : ::: . : : .* * * **: :: ::.**. * :* **:* :. *:*:: **. : :* *..**:* *:*. : *. *:**. * * . . :*. .** :: ", "identical_positions": 71, "similar_positions": 98, "identity": "17.4%" }, { "cls_id": "homologset.agr.MGI:1321393", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z2Y1-1", "uniprot_id": "TIM_RAT", "id": "Q9Z2Y1-1", "name": "Protein timeless homolog", "aln": "--------------MDLYMMNCELLATCSALG------YLEGGTYHKEPDCLESVKDLIRYLRHEDETR---DVRQQLGAAQILQSDLLPILTQHRQDKPLFDAVIRLMVNLTQPALLCFGS-VPKDPTVRHHFLQVLTYLQAYKEAFASEKAFGVLSETLYELLQLGWEDRQEEDNLLIERILLLVRNILHVPANLEQEKRIDDDASIHDRLLWAIHLSGMDDLLLFLSSSSAEQQWSLHVLEIISLMFRDQKPEQLAGVGQGRLAQERSTDLAELEVLRQREVAEKRARALQRGNRHSRFGGSYVVQGLKSIGERDVVFHKGLHNLQNYSSDLGKQPRRVPKRRQAAQELSVHRRSVLNVRLFLRDFCSEFLENCYNPLMGAVKDHLLR-EKAQQHDETYYMWAMAFFMAFN-RAAAFRPGFVSETLSIRTFHFVEQNLTNYYEMMLTDRKEAASWARRMHLALKAYQELLATVNEMDMCPDDA-VRESSRIIKNNIFYMMEYRELFLALFRKFDERYHPRSFLCDLVETTHLFLKMLERFCRSRGNLMVQNKRKKR-KKKKKAQEQGVAFS---RSPEELQAMWSALAERLLQC-AQEPELSVDS-IIPFDAASEVPVEEQRVEAMVRIQDCLVAGQAPQALALLRSAREVWPEGNVFGSPVISPGEEMQLLKQILSATLPRQQEPVEGDAEEEDEEEEEEEEEELQVVQVSEKE-------FKFLDYLKRFACSTIVRAYVLLLRSYRQNSAHTNHCIAKMLHRLAHDLGMEALLFQLSLFCLFNQLLS----DPAAAAYKELVTFAKYILGKFFALAAVNQKAFVELLFWKNTSVVREMTQGYGSLDSGSCSHRAPVWS------SEEEAQLQELYLAHKD-----VEGQDVVETILAHLKAVPRTRKQVIHHLVRMGLADSVKDFQ--RKGTQ-IVLWTEDQELELQRLFEEFQDSDDVLGHIMKNITAKRSRARVVDKLLALGLVSERRQLHKKRRK---------------KLAPSCMQNGEESQRDAWQEDPEEEEEKEGLPESEGEENEEDLLAGQVQGSSSLSA---ENLR------QSLCQDGLSAPLLWLQSSLIRAADDREEDG-CSQAIPLVPLTEENEEAMENKQFQHLLRKLGIRAPCSGQETFWRIPAKLSSTQLRRVAASLSERENK-EEREEEPEPNPGVPGEQSPSE----EHQVRAPRALLSARKRK----AGLVFPKEE--------ATGEEEWKSVPKKQQLLDSDEED---------------------------------------------------------------------TDDERGGQ--------AAVSGTLRIHKEKRFLVEDEDEDY----------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R1X4-1", "uniprot_id": "TIM_MOUSE", "id": "Q9R1X4-1", "name": "Protein timeless homolog", "aln": "--------------MDLYMMNCELLATCSALG------YLEGGTYHKEPDCLESVKDLIRYLRHEDETR---DVRQQLGAAQILQSDLLPILTQHRQDKPLFDAVIRLMVNLTQPALLCFGS-VPKDSSVRHHFLQVLTYLQAYKEAFASEKAFGVLSETLYELLQLGWEDRQEEDNLLIERILLLVRNILHVPANLEQEKSIDDDASIHDRLLWAIHLSGMDDLLLFLSSSSAEQQWSLHVLEIISLMFRDQTPEQLAGVGQGRLAQERSTDVAELEVLRQREMAEKRARALQRGNRHSRFGGSYIVQGLKSIGEKDVVFHKGLHNLQNYSSDLGKQPRRVPKRRQAAQELSVHRRSVLNVRLFLRDFCSEFLENCYNPLMGAVKDHLLR-ERAQQHDETYYMWAMAFFMAFN-RAATFRPGLVSETLSIRTFHFVEQNLTNYYEMMLTDRKEAASWARRMHLALKAYQELLATVNEMDMCPDEA-VRESSRIIKNNIFYMMEYRELFLALFRKFDERYHPRSFLRDLVETTHLFLKMLERFCRSRGNLMVQNKRKKR-KKKKKVQDQGVAFS---QSPGELEAMWPALAEQLLQC-AQDPELSVDP-VVPFDAASEVPVEEQRVEAMVRIQDCLTAGQAPQALALLRSAREVWPEGNAFGSPVISPGEEMQLLKQILSTPLPRQQEPEEGDAEEE---EEEEEEEELQVVQVSEKE-------FNFLEYLKRFASSTIVRAYVLLLRSYRQNSAHTNHCIAKMLHRLAHGLGMEALLFQLSLFCLFNRLLS----DPAAAAYKELVTFAKYIIGKFFALAAVNQKAFVELLFWKNTAVVREMTQGYGSLDSGSSSHRAPLWS------PEEEAQLQELYLAHKD-----VEGQDVVETILAHLKVVPRTRKQVIHHLVRMGLADSVKEFQK-RKGTQ-IVLWTEDQELELQRLFEEFRDSDDVLGQIMKNITAKRSRARVVDKLLALGLVSERRQLYKKRRK---------------KLAPSCMQNGEKSPRDPWQEDPEEEDEHLPEDESEDEESEEGLPSGQGQGSSSLSA---ENLG------ESLRQEGLSAPLLWLQSSLIRAANDREEDG-CSQAIPLVPLTEENEEAMENEQFQHLLRKLGIRPPSSGQETFWRIPAKLSSTQLRRVAASLSQQENE-EEREEEPEP--GVPGEQGPSE----EHRTEALRALLSARKRK----AGLGPTEEE--------ATGEEEWNSAPKKRQLLDSDEE-----------------------------------------------------------------------EDDEGRR--------QAVSGTPRVHRKKRFQIEDEDD------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UNS1-1", "uniprot_id": "TIM_HUMAN", "id": "Q9UNS1-1", "name": "Protein timeless homolog", "aln": "--------------MDLHMMNCELLATCSALG------YLEGDTYHKEPDCLESVKDLIRYLRHEDETR---DVRQQLGAAQILQSDLLPILTQHHQDKPLFDAVIRLMVNLTQPALLCFGN-LPKEPSFRHHFLQVLTYLQAYKEAFASEKAFGVLSETLYELLQLGWEERQEEDNLLIERILLLVRNILHVPADLDQEKKIDDDASAHDQLLWAIHLSGLDDLLLFLASSSAEEQWSLHVLEIVSLMFRDQNPEQLAGVGQGRLAQERSADFAELEVLRQREMAEKKTRALQRGNRHSRFGGSYIVQGLKSIGERDLIFHKGLHNLRNYSSDLGKQPKKVPKRRQAARELSIQRRSALNVRLFLRDFCSEFLENCYNRLMGSVKDHLLR-EKAQQHDETYYMWALAFFMAFN-RAASFRPGLVSETLSVRTFHFIEQNLTNYYEMMLTDRKEAASWARRMHLALKAYQELLATVNEMDISPDEA-VRESSRIIKNNIFYVMEYRELFLALFRKFDERCQPRSFLRDLVETTHLFLKMLERFCRSRGNLVVQNKQKKRRKKKKKVLDQAIVSGNVPSSPEEVEAVWPALAEQLQCC-AQNSELSMDS-VVPFDAASEVPVEEQRAEAMVRIQDCLLAGQAPQALTLLRSAREVWPEGDVFGSQDISPEEEIQLLKQILSAPLPRQQGPEERGAEEE-EEEEEEEEEELQVVQVSEKE-------FNFLDYLKRFACSTVVRAYVLLLRSYQQNSAHTNHCIVKMLHRLAHDLKMEALLFQLSVFCLFNRLLS----DPAAGAYKELVTFAKYILGKFFALAAVNQKAFVELLFWKNTAVVREMTEGYGSLDDRSSSRRAPTWS------PEEEAHLRELYLANKD-----VEGQDVVEAILAHLNTVPRTRKQIIHHLVQMGLADSVKDFQ--RKGTH-IVLWTGDQELELQRLFEEFRDSDDVLGHIMKNITAKRSRARIVDKLLALGLVAERRELYKKRQK---------------KLASSILPNGAESLKDFCQEDLEEE-ENLPEEDSEEEE-EGGSEAEQVQGSLVLSN---ENLG------QSLHQEGFSIPLLWLQNCLIRAADDREEDG-CSQAVPLVPLTEENEEAMENEQFQQLLRKLGVRPPASGQETFWRIPAKLSPTQLRRAAASLSQPEEE-QKLQPELQP--KVPGEQGSDEEHCKEHRAQALRALLLAHKKK----AGLASPEEED-------AVGKEPLKAAPKKRQLLDSDEEQ---------------------------------------------------------------------EEDEGRNR--------APELGAPGIQKKKRYQIEDDEDD-----------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FGL0-1", "uniprot_id": "E7FGL0_DANRE", "id": "E7FGL0-1", "name": "", "aln": "--------------MDLYMMNCELLATCSALG------YLEGDVYHKEPDCLESVKDLIRYLRHEDDAR---DIRQQLGAGQILQNDLLPIITQHTQDKPLFDACIRLMVNLTQPALLCFGK-IPDDPAFRHHFLQVTSYLQAYKEAFADEKVFTVLSETLYNLLQLDWEQRDEEDNLLIERILLLVRNVLHVPADPYEEKNVDDDASVHDKLLWAIHISGLDDLLKFLACAQSEQQWSFHILEIISLMFRDQTAELLVSAGQMRSAQEKQKDMQELELLRQKETAEKRSRTLMRGTRHSRFRGSYVIEGLKSIGENDVVYHQGLHNFKSYSHDLGKAVRRVPKRKQMAKDSDSHRRSALNVRLFLREFCIDFLENCYNRLMYLVKEGLIR-ERAQQHDETYYMWALTFFMAFN-RLQNFKPDVVSETISIRTFHFIEKNITNYYEMMLTDKSDATSWSRRMHLALKAYQELLLTVNEMDRSKDEN-IRHSSSVIKSNIFYLMEFREIFLTLLRKYDERLQPRSFLRDLVESAHLFLRMLERFCKGRNNLVVQKKRVKRKKRSQKKPEMET-------SAEDLEQSWQIVSEELRASGFQLPESLTEG-AVPFDAASDTPVNEQRTEALVRIQDCLMSRAGPEALSLLRAARAVWPEGDTFGSVEVEPEEELELLKQILFTKLPR-TVPLDSAVEEE-DGDELVEEEELESVAVSETE-------FNFLDFIKRFAHPNIVRPYVILLRSYSQNSPHTNHCVTRMLHRLAVDLKMEALLYQLSVFSLFNKILG----DPAAAAYQELVKFAKYVLNRFFVFAATNNKAFVELLFWKNVGAVREMTEGY--TKDGEGSKKKSKWT------PEEEAELQRLYEEHKD-----SGVPDVVETLLPLLSSS-RTRREVVSHLVSMGLVDSVKDLKKEKKGTR-IVLWTEEQEQELQGLFEDFQDSDDVLGNILKRITAKRSRARIVDKILSMGLVSDRKELYKKRQRGAHGKSTGMTEEQFFDMTGEMQEKDIEDEEDDDEDDDDKSDQDEDEQHYEKQQTVRSAKKHQKSTSRDISS---EKIHSLRKMVQALQLEGLSGPVLWLQNSLNRTADDREEDG-VSHPVALVPLTEENEDAMENRSFQKLLRAVGIRAPSEGQETFWRISSSLSVNQLRTLAASLEPLEETGAEGDSEEKDSRSVEDDENENDN--QEMRAQALRALLLSRQRK----HTSAKPKDSPSQEDISDSVESSEQKISKKRSRVLDDDEDK---------------------------------------------------------------------DDEDQKDSPSQEDISDSVESSEQKISKKRSRVLDDDDEDDDDQKDVDPSSRSSERDSPAAPAKRRYTRVLSDEEEEDN--------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8INH7-1", "uniprot_id": "Q8INH7_DROME", "id": "Q8INH7-1", "name": "", "aln": "----------------MSILLADIDATCAALG------YSDGQKYQAEPDAAEGLKHLIWILRRDLDNH---EYRRHLGRSKVLQTDLVYMLPDYVHHEELSDLLIRLLVILTNPTLLLYREGAPKDNHGRKVFMELIDILQGYKAAFAKDKVWSALFEKLKQALEIAFAIRSEEQNLLIERILVLVRNVLQVPANPEAECRADNDASLHDQVIWALHQTGMLDLVLFVISSPDEEQFHLHGLEIVCLLFREQSAESLADASLQRSLSEKQRDQQELLAARRRERARRQARPPP--GRHSRFGGTYVIRNMKSVSDRDVICHQALERVSSIDFDREKQQQKRSHR-HIQEEAQVTRRSAFTVRLCLREYCIEVLRSAYNTLVRQVRRVLERNAGSSSHDDSYLLWAIRFFMEFN-RLSGLQLQLVSESLSVQCFHWVLTRMQHDMDMIVSDKKQARLWAKRLHVALLTFRELLQSLLALQKLKDDNNARALFDMLLNNVCYVLEYRETVLHLLMNYNEAHSTKVFLRDVVETANVFIKMMERFCQDSVVVQDKKRGRGASRKKKQAATKSKPPAAPQPTEEELSSKWAELATEVCSLLSTELEMPEDEQPLPFDAASEKSIDDQREDCMIRINKLLRSEKLDQAIALLRAAREVWPENEVFGAISAAPEDELLLLREIFMSNITTVESEDKENEKDQKQDEYEDEDDDLDNEEYEEQDNGLTEKTFKFDDFARRLLNPKIVRACTLVLSDWADIPTRSLKAAVTILHRIAYGCKCAGMLFQAKLFRIFQQVFS----VERDVHQEELRRLAIFVVRKFVEVAPTNPKIYAELLFYKGIREANELESGYCDAYEAG---TKGAWT------EEQESELRFLFEENQRNP---ETDKDVIDWILDNLVDKTRNRRTVLKKLKELGLLFKAPTKRSTKSAQSGKNVWQPEEDDELRSLYDQHRIEPDCLERLVNEFAERRSKQQIIKRMLQIHLIADKSEILPAKKG-----------------RGKDKPKKDVEMEGEGDEFDFAEEPMFEDQGYKKPKSKPKKVQKRQMVRTPLDVGTIR------ALIGQVDSEKYQSAIEWLQECLQDASEDTEEAVEDDDGVPLLPLMENQKNAMEDGDFQKVLVALGMQPPISGMEAYWRIPIYLNSADLILRSKILAGEEVDAEPEDEAADDEDGEEAEESDEEEDFLEKHSRQRKENIATQQQRKLDSLMFNQSDDETEQRAPPKAKDKPKASEKKAKRKVKGKAKESKDCNDDGTDKAELEKPNTDDLFNQLRAKRATKIKLSDMALNESTNAAQEADDDAFNFNSEDYRARLLELEDEEQNSKDADENGGDKENITNKSLQRARRVNVIDSDSDNDDDGALPADKTNKRPRSDDDGDSGHMDANAEEDSDEEANFLARKKPAKVDGEPAKRRRLAIIDDDDEDDF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53840-1", "uniprot_id": "TOF1_YEAST", "id": "P53840-1", "name": "Topoisomerase 1-associated factor 1", "aln": "MSADLQQGTTNAADFSLTVLRARIALLATAIGGPDYTSQIDPPPYKLGDDCLACLKDLKRWFKLVDDQQKRWDVAMAVAEYRILTDDLLPILIDWENKCSLAAKLAKNNPDHEEFRNKAYYD----KIALNCLQLLVLMTWPLIVTEQSSSNQITLYGELKKHQLVYKKTILSMESGKVLRAAIRLALDVIKIDRLSRTPRDNMVLKLVLNFFRNVIAIEPGEFTINTKKSMPKKGITSIDTLPPNVSMDDISLNTVISSFHKNKVFGFLLTLTSSLSKEFDQDFINIPLLEIMFYFTKDVNQELLFPRQFETGTHSKVVNKNESSSANNIVTSAGFELSKLLQKEHQMRKNVIKHTSARHSRFGG---LLSIQTPDKTRLTVSGSQALVDEKIALQKLDDSKKWNKRIIKKHQSVAAEGLPNSLLNSQTGKAIFFTESNGKHFKEFIN-------------NFIDSGFNILLHSVTNYFTTEQDR----MVTLEQVEYLLFFAWFVKYQLLRSKIDNSADIKQVSEALKEVTFILVSSLLRSAYDLKNWTVT------------------------------HAGMIAFNELLNLVSRTKAAQEEDS------TDIEFIVSRLFSDERIQLLSNLPKIGSKYSLQFMKSCIELTHS--VLKVLEQYSDDKTLVIEGKSRR--QKKFNISEGDITKLIEEENVDRDEALDILTSSLRS-----IEVNFQKVQANYMTEPVIETYINFLERFRELEDDSIKKVFSFFHRVFVQAKEQALLFRFDLIILLREMLSPDGLDRMSRSRKYVSQFSDYFLARLKKRLKKSPAWFVGLLFPPLHNSEVGFYQRYGEYNVLNNESMYAAPASQFKPIPDEEALPPSILLDMKYGVLVSTLLDDGKTELLDQLLKHITHTLDIFKSWLTVNVNAGKETVNPPNEYFTLTGVLNNDPIFKDKDYRALLLLIGYSIPRKINEPCFLPGTVEVSDLTVSCELVKKYLSTPFETPN---------------GLPSSSYLLRVRSEKDSFSHNEQDGWEGDDDYDYNDPYIVPDDQILSKSDAAYFKD------------LDNNASDKLKGTKFSKGIARSKKKDKRKRRK--GEAKTNLPMFGDQDDERPQTVRERHGVFSKEFISDSEDDEDLMNPIFFENETYMRWLLDKNNGQLTEDRYIQFAKFAAERMNNGGVVTGDYTSLFGGSIPSIESIRATE----SSSFAPDKSLISLASHVASEMSIFDVNNNNNNQLSDDDVNSES------------------------------------------------------------------RNSLGSSQPSNSQNMFQSEVYSRKESTKRSLEASAADESDEDEEAIRLFGKKSRVVLSQGDSDD----------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: . : .:*:* : *: *. :*.* :: : : : :. ::* **: :: : :. * : : : . . . : : :..: * . * . *.. ::. : *. ::::: : . .: : . : :. * : . : . : .* :: . :. . . ::: . .:: :: . . : :: : .. : *. *: .. . * * : .: : * :: .: : :: : : :.: . : ::: :. :. ** :: :: : : .: : * : :: : . : * : ::: : * . . . : : : : :. : ::: . * :: ::::. : . .: . :: ::. . . : .:: *: . . .:* . . ::.. .* : : : : ::**: .:*:: .:: ::..::. : : :: :.: :: . :. *** : . * : ::*: : : * :* * :. :.: . .. : : : : : . ::. . .: . : *: . . . . .. .. : :. : . . . :. :. .. . :*: ::.: : :: . . : . :. : . : . . : . .... : . . . .. . :. : :. ", "identical_positions": 43, "similar_positions": 318, "identity": "2.96%" }, { "cls_id": "homologset.agr.MGI:1321394", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0RB87-1", "uniprot_id": "M0RB87_RAT", "id": "M0RB87-1", "name": "Growth/differentiation factor 2", "aln": "MSPGAFRVVLLTLLLLVCPTQQKPLQSWGQASPGGNARSSLGLSGSRE-EGVFDLKMFLENMKVDFLRSLNLSGIPSQDKTRAEPPQYMIDLYNRYTTDKSSTPASNIVRSFSVEDAISTAATEDFPFQKHILIFNISIPRHEQITRAELRLYVSCQNHVDSTHGLEGNMVVYDVLDVDETWDSASGTKTFLVSQDIQD--EGWETLEVSSAVKRWVRADSTTNKNKLEVTVQRHREGCSTLDISVPPGSQNLPFFVVFSNDRSNGTKETRLELKEMIGHEQETVLVKTSKNAYQEAGESREEEERIDGYTAVGPLLARRKRSTGAASSHCQKTSLRVNFEDIGWDSWIIAPKEYDAYECKGGCFFPLADDVTPTKHAIVQTLVHLKFPTKVGKACCVPTKLSPISILYKDDMGVPTLKYHYEGMSVAECGCR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WV56-1", "uniprot_id": "GDF2_MOUSE", "id": "Q9WV56-1", "name": "Growth/differentiation factor 2", "aln": "MSPGAFRVALLPLFLLVCVTQQKPLQNWEQASPGENAHSSLGLSGAGE-EGVFDLQMFLENMKVDFLRSLNLSGIPSQDKTRAEPPQYMIDLYNRYTTDKSSTPASNIVRSFSVEDAISTAATEDFPFQKHILIFNISIPRHEQITRAELRLYVSCQNDVDSTHGLEGSMVVYDVLEDSETWDQATGTKTFLVSQDIRD--EGWETLEVSSAVKRWVRADSTTNKNKLEVTVQSHRESCDTLDISVPPGSKNLPFFVVFSNDRSNGTKETRLELKEMIGHEQETMLVKTAKNAYQVAGES-QEEEGLDGYTAVGPLLARRKRSTG-ASSHCQKTSLRVNFEDIGWDSWIIAPKEYDAYECKGGCFFPLADDVTPTKHAIVQTLVHLKFPTKVGKACCVPTKLSPISILYKDDMGVPTLKYHYEGMSVAECGCR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UK05-1", "uniprot_id": "GDF2_HUMAN", "id": "Q9UK05-1", "name": "Growth/differentiation factor 2", "aln": "MCPGALWVALPLLSLLAGSLQGKPLQSWGRGSAGGNAHSPLGVPGGGLPEHTFNLKMFLENVKVDFLRSLNLSGVPSQDKTRVEPPQYMIDLYNRYTSDKSTTPASNIVRSFSMEDAISITATEDFPFQKHILLFNISIPRHEQITRAELRLYVSCQNHVDPSHDLKGSVVIYDVLDGTDAWDSATETKTFLVSQDIQD--EGWETLEVSSAVKRWVRSDSTKSKNKLEVTVESHRKGCDTLDISVPPGSRNLPFFVVFSNDHSSGTKETRLELREMISHEQESVLKKLSKDGSTEAGES-SHEEDTDGHVAAGSTLARRKRSAG-AGSHCQKTSLRVNFEDIGWDSWIIAPKEYEAYECKGGCFFPLADDVTPTKHAIVQTLVHLKFPTKVGKACCVPTKLSPISVLYKDDMGVPTLKYHYEGMSVAECGCR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QWZ4-1", "uniprot_id": "GDF2_DANRE", "id": "F1QWZ4-1", "name": "Growth/differentiation factor 2", "aln": "-----MWRVGHLLLLMSIVFRITEEKSLGDAGSLEDSMFIQEQKLVED-DDLNKVESFLGFMKEDFLRKLNLSGVP-QEHRKVQPPQFMIELYNRYASDKNSIPRSDVIRSFVVQDVIYSIRQGNK--TQHRLLFNVSIPNHEEITSVQLRLFTLWHRHKPACDDLFTSINVYDVE-----YEQNAKILHLLDGRDVRESINTWEAFDVTGAVRIWH--ESRRGAGEIQVEVQHS---CDSFDISLSLEDNSSAVVIVFSDDLGNRKEESMRKVKEMLVREQQ----------------------QVGNQAPVSNRHRRRKRKAK--NNYCRRTSLKVNFKDIGWDKWIVAPPEYDAYECKGVCYFPLTDDVSPSRHAVIQTLVNLSNPKKANMACCVPTKLDPIAVMYQE-KGVITVRHLYEEMKVAKCGCR", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . * *: : . :. ... :: : .:: ** :* ****.*****:* *:: :.:***:**:*****::**.: * *:::*** ::*.* : :* *:**:***.**:** .:***:. :.. . ..* .: :*** ::. : :* .:*::: : **:::*:.**: * :* . .:::* *: *.::***:. ... ...:***:* .. .:*: :::**: :**: .. .... ****.: ..:*::***:***:*****.**:** **:****** *:***:***:*::**::****:*. *.*.. ********.**:::*:: ** *::: ** *.**:****", "identical_positions": 145, "similar_positions": 144, "identity": "33.49%" }, { "cls_id": "homologset.agr.MGI:1321395", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A917-1", "uniprot_id": "D4A917_RAT", "id": "D4A917-1", "name": "Latent-transforming growth factor beta-binding protein 4", "aln": "MRRPGLGCHCPLLLLLLLPAATSAS-GPSSSPSPIQAVEDAVVPGHQAGAAACRCCLAQTPRSSHCTRASCRVRSCPPGRCTDQQGCLTPTPSVPSPSRSPVEKRQVSLNWQPLTLQEARALLRQRRPRGPWARALLKRRPPHRAPAGQARVLCPLICHNGGVCVKPDRCLCPPDFAGKFCQLHSSGARPPAPAMPGLTRSVYTMPLANHRDDEHGVASMVSVHVEHPQEASVVVHQVERVSGPWEEANSEALARAEAAARAEAAAPYTVLAQSAPREDGYSDASGFGYCFRELRGSECASPLPGLRTQEVCCRGEGLAWGVHDCHPCAEHLGNSNRVSGPNGLCPTGFERVNGSCVDVDECATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPCYRVLQDGGCSLPILRNITKQICCCSRVGKAWGRGCQLCPPYGSEGFREICPAGPGYHYSASDLRYNTRPLNPDPPRVTFNQPRAPPVTLRPPTGFLPTRRPEPRPDPGPQPELRPRPEPQPRPE------------------------------------FPLPSIPAWTGPEIPESGTSSSMCQRNPQVCGPGRCVSRPGGYTCACDPGFRLGPQGTRCIDVDECRRVPTPCAPGRCENTPGSFRCVCGTGFRAGPRATECLDVDECRRVPPPCDRGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGACENLPGSFRCVCPAGFLGSACEEDVDECAQQPPPCGPGRCDNTLGSFHCACPAGFRSRGPGAPCQDVDECARSPSPCAYGRCENTEGSFKCVCPTGFQPNAAGSECEDVDECENHLACPGQECVNSPGSFQCRACPVGYHLHRGRCTDVDECNSGTP-CGLHGQCTNAQGSFHCSCSTGYRAPSGRPGPCADINECLEGDFCFPHGECLNTDGSFTCTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDIDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHPGPEGTCDDVDECREYGSAICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAMCQNLPGSFQCVCDQGYEGARDGRHCVDVNECETLQGVCGSALCENVEGSFLCVCPTSPEEFDPMTGRCVPPRTPAGTFPGSQPQAPASPSLPARPPAPPPPRRPSPPRQGPVSSGRRECYFDTAAPDACDNILARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLVPSGDLSARRDVDECQLFQDQVCKSGVCVNTAPGYSCYCNNGFYYHAHRLECVDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSRRRCVSNESQSLDDNLGVCWQEVGPDLVCSRPRLDRQATYTECCCLYGEAWGMDCALCPAQDSDDFEALCNVLRPPAYGPPRPGGFGLPYEYGPDIGPPYQSLPYGPDLYPPPVLPYDPYPPPPGPFARREAPYGAPPFEMPDFEDDGDPYGETEAPDPPSRGTGWPYRSRDTRGSFPEPEESSERGSYTGALSEPYEGLEAEECGILDGCAHGRCVRVPEGFTCDCFDGYRLDITRMSCVDINECDEAEATSPLCVNARCVNTDGSFRCICRPGFAPTHQPHHCAPARPRA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K4G1-1", "uniprot_id": "LTBP4_MOUSE", "id": "Q8K4G1-1", "name": "Latent-transforming growth factor beta-binding protein 4", "aln": "MRRPGLGGPCPLLLLLLLPAATSAS-GSSPSPSPS-PIEKAVVPSHQAGVAACHCCLDQTPKSSRCTRASCRVRNCPPAKCTGLEGCLTPTPSVPSPSRSPVEKSQVSLNWQPLTLQEARALLRQRRPRGPWARALLKRRPPHRAPAGQARVLCPLICHNGGVCVKPDRCLCPPDFAGKFCQLHSSGARPPAPAMPGLTRSVYTMPLANHRDDEHGVASMVSVHVEHPQEASVVVHQVERVSGPWEEANPEALARAEAAARAEAAAPYTVLAQSAPREDGYSDASGFGYCFRELRGSECASPLPGLRTQEVCCRGEGLAWGVHDCHPCAEHLRNSNQVSGPNGPCPPGFERVNGSCVDVDECATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPCYRVLHDGGCSLPILRNITKQICCCSRVGKAWGRGCQLCPPYGSEGFREICPAGPGYHYSASDLRYNTRPLNQDPPRVTFNQPRVPPATPRPPTGFLPTRRPEPRPDPGPQPEPRPRPEPRPRPESRPRPEPRPRPEPRPQPESQPRPESRPRPESQPWPEFPLPSIPAWTGPEIPESGPSSSMCQRNPQVCGPGRCVPRPSGYTCACDPGFRLGPQGTRCIDIDECRRVPTPCAPGRCENTPGSFRCVCGTGFQAGPRATECLDVDECRRVPPPCDRGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGVCENLPGSFRCVCPAGFRGSACEEDVDECAQQPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECSRSPSPCAYGRCENTEGSFKCVCPTGFQPNAAGSECEDVDECENRLACPGQECVNSPGSFQCRACPVGHHLHRGRCTDVDECSSGTP-CGLHGQCTNTKGSFHCSCSTGYRAPSGQPGPCADINECLEGDFCFPHGECLNTDGSFTCTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDIDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHPGPEGTCDDIDECREYGSAICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAMCQNLPGSFQCVCDQGYEGARDGRHCVDVNECETLQGVCGSALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRAPAGTFPGSQPQAPASPSLPARPPAPPPPRRPSPPRQGPVSSGRRECYFDTAAPDACDNILARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLVPSGDLSARRDVDECQLFQDQVCKSGVCVNTAPGYSCYCSNGFYYHAHRLECVDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSRRRCVSNESQSLDDNLGVCWQEVGPDLVCSRPRLDRQATYTECCCLYGEAWGMDCALCPAQDSDDFEALCNVLRPPAYGPPRPGGFGIPYEYGPDIGPPYQSLPYGPDLYPPPVLPYDPYPPPPGPFARREAPYGAPPFDMPDFEDDGGPYGESETPDPPSRGTGWPYRSRDTRGSFPEPEESSERGSYTGALSEPYEGLEAEECGILDGCPHGRCVRVPEGFTCDCFDGYRLDITRMSCVDVNECDEAEATSPLCVNARCVNTDGSFRCICRPGFAPTHQPHHCAPARPRA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N2S1-1", "uniprot_id": "LTBP4_HUMAN", "id": "Q8N2S1-1", "name": "Latent-transforming growth factor beta-binding protein 4", "aln": "MPRPGTSGRRPLLLVLLLPLFAAATSAASPSPSPSQVVEVPGVPSRPASVAVCRCCPGQTSRRSRCIRAFCRVRSCQPKKCAGPQRCLNPVPAVPSPSPS-VRKRQVSLNWQPLTLQEARALLKRRRPRGPGGRGLLRRRPPQRAPAGKAPVLCPLICHNGGVCVKPDRCLCPPDFAGKFCQLHSSGARPPAPAVPGLTRSVYTMPLANHRDDEHGVASMVSVHVEHPQEASVVVHQVERVSGPWEEADAEAVARAEAAARAEAAAPYTVLAQSAPREDGYSDASGFGYCFRELRGGECASPLPGLRTQEVCCRGAGLAWGVHDCQLCSERLGNSERVSAPDGPCPTGFERVNGSCEDVDECATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNITKQICCCSRVGKAWGRGCQLCPPFGSEGFREICPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPATSRPSAGFLPTHRLEPRPEP--------RPDPRPGPE------------------------------------LPLPSIPAWTGPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQEVGADLVCSHPRLDRQATYTECCCLYGEAWGMDCALCPAQDSDDFEALCNVLRPPAYSPPRPGGFGLPYEYGPDLGPPYQGLPYGPELYPPPALPYDPYPPPPGPFARREAPYGAPRFDMPDFEDDGGPYGESEAPAPPGPGTRWPYRSRDTRRSFPEPEEPPEGGSYAGSLAEPYEELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRCICRPGFAPTHQPHHCAPARPRA", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* *** . ****:**** ::*: ..*.**** :* . **.: *..*.*:** **.: *:* ** ****.* * :*:. : **.*.*:***** * *.* ******************::****** .*.**:****:*****:* *******************************************:*****************************************************:.**:*******************************************.****************** *********: *:*:* **::**.*:* **.********* *****************************************************:***:***********************************:*****************************. :****::.***. *.* **.:*****:* ****:* **:*:* ** :*****************.**.**************:.**.*******.****.********:*******.*********:*********.**:*****:********:******* *******************************************.*:************** *************:************ **************************:***.**:***********:**** *****:*************:******************:** *:*************.**:* ** **:***::***:***:.*******:******:**********************:***********************************************************:**********************************.********:***:***. ************************************************:**********:****************************:***************.****************:.*************** ******.** *****.******.*****************************************************************.****** **********:********************.**:***::****:*************************************:***********************.*****:***********************************************.********:*******:*****.*****:*****.*********************** *:********.****:*:* **. ** ********* *******..* ***:*:*:**** ************.:************ ********:***:***:********:*********:******************************", "identical_positions": 1420, "similar_positions": 148, "identity": "85.08%" }, { "cls_id": "homologset.agr.MGI:1321396", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97814-1", "uniprot_id": "PPIP1_MOUSE", "id": "P97814-1", "name": "Proline-serine-threonine phosphatase-interacting protein 1", "aln": "MMAQLQFRDAFWCRDFTAHTGYEVLLQRLLDGRKMCKDVEELLRQRAQAEERYGKELVQIARKAGGQTEMN-------SLRTSFDSLKQQTENVGSAHIQLALALREELRS-----LEEFRERQKEQRKKYEAIMDRVQKSK-----------------------------LSLYKKTMESKKAYDQKCRDADDA----------------------------------------------------------------------------------------------------------------------------------------EQAFERVSANG--HQKQVEKSQNKAK---QCKESATEAERVYRQNIEQLERARTEWEQEHRTTCEAFQLQEFDRLTILRNALWVHCNQLSMQCVKDDELYEEVRLTLEGCDVEGDINGFIQSKSTGREPPAPVPYQNYYDREVTP-------------LIGSPSIQPSCG-----------------------VIKRFSG-------LLHGSPKTT-PSAPAASTETLTPTPERNELVYASIE--VQATQGNLNSSAQDYRALYDYTAQNSDE------LDISAGDILAVIL--------------------------------------------------------------------EGEDG-------------WWTVE----------------------RN-GQRGFVPGSYLEKL-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43586-1", "uniprot_id": "PPIP1_HUMAN", "id": "O43586-1", "name": "Proline-serine-threonine phosphatase-interacting protein 1", "aln": "MMPQLQFKDAFWCRDFTAHTGYEVLLQRLLDGRKMCKDMEELLRQRAQAEERYGKELVQIARKAGGQTEIN-------SLRASFDSLKQQMENVGSSHIQLALTLREELRS-----LEEFRERQKEQRKKYEAVMDRVQKSK-----------------------------LSLYKKAMESKKTYEQKCRDADDA----------------------------------------------------------------------------------------------------------------------------------------EQAFERISANG--HQKQVEKSQNKAR---QCKDSATEAERVYRQSIAQLEKVRAEWEQEHRTTCEAFQLQEFDRLTILRNALWVHSNQLSMQCVKDDELYEEVRLTLEGCSIDADIDSFIQAKSTGTEPPAPVPYQNYYDREVTP-------------LTSSPGIQPSCG-----------------------MIKRFSG-------LLHGSPKTTSLAASAASTETLTPTPERNEGVYTAIA--VQEIQGNPASPAQEYRALYDYTAQNPDE------LDLSAGDILEVIL--------------------------------------------------------------------EGEDG-------------WWTVE----------------------RN-GQRGFVPGSYLEKL-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LX61-1", "uniprot_id": "Q1LX61_DANRE", "id": "Q1LX61-1", "name": "Proline-serine-threonine phosphatase-interacting protein 1", "aln": "-MTALQFKDYFWGPKFTSNSGYEILIQRLCDGRRACKDMEELLKMRAMAEERYGKELITIARKTGGQTEIG-------TLKASFDQLKAQMENIGNLHIQLSGMLREEAKR-----MEHFRERQKEQRKKFEGVMEKVQKIK-----------------------------VSLYKKTMESKRTYEQRCREADEA----------------------------------------------------------------------------------------------------------------------------------------ELTAEKLNSTSTVTPKQSEKTQNKAK---QCRDAATDAEKQYISNIEQLDKIRQEWETTHELTCEVFQQQEDDRINILRNAIWVHCNHFSMQCVKEDECYEEVRTTLEMCDITEDINSFIKTKSIGNTPSVPIVFENYYEKEQQ--------------ADSNGIIRFGGG-----------------------VMKRFSN-------LLQGNCAIGSRNNNECIVPSAPPSADNSDGVYASIPGFPQETSNITASESGKYQAIYDYVAQGPDE------LSISVGEVLLVVE--------------------------------------------------------------------QGGDG-------------WWTVE----------------------RN-GQTGLVPGSYLEII-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AC58G0H7-1", "uniprot_id": "A0AC58G0H7_DANRE", "id": "A0AC58G0H7-1", "name": "", "aln": "--MALLFCDSFWGTDFTDQSGYEAILQRLQDGRHMCKDVEELLKMRALAEEKYGRDLVAIARKAEGQTEIG-------TLKASFDKFKEEIEKTGNLHIQLSERIKEEVLK-----IEVFREHQREQRKKLEEIIEKLQKPK-----------------------------MVLHKKTMESKRLYEQRCKEADES----------------------------------------------------------------------------------------------------------------------------------------EQALGKKTNVNTSTHRQSEKVMNRAR---LCRQAANLAEKQYRWNVDQLGKTCQDWESTYRSACEVFQQQESERINILRCVLWEHCNLLSKQCVQDDDCYEEVRKILEQCDIVADNNNFIKMKKTSSHPPAPIEFQCYSDADTNGGVRRIETNRLSVVLSGMSFIGFPEAGNNSGAKYTPDQQRIGVTEEKYMVLYEFKAQEDDELSISKGQVVTITEKDSQEEVDRFKADGKNHMSTESWVGLSKPSATGEWVWSDGSQESFLTWKSGQPNDPDTDFCAKSTNGELFDFNCNQKYPFFCYYWM--------------PPLILVMELKSWEEAFQYCRTKHNGLACLPTRLHLLQVQNHTEASDAPSVWTGLRFLAGSWFWVNGEALGTLVSLQACPANALYCGSRNLGAKSWENRNCIDKLNFVCY--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P43556-1", "uniprot_id": "RGD2_YEAST", "id": "P43556-1", "name": "Rho-GTPase-activating protein RGD2", "aln": "---MLSFCDYFWSEDLVS--GLDVLFDRLYHGCEQCDLFIQLFASRMQFEVSHGRQLFGIEAGMDNLKAVQEDEDEGVTVSRALRGILQEMSQEGTHHLTIASNIESLVLQPFSKWCIEHRERIQYSEKTLLTNVNNFRKSKKYVGKLEKEYFNKCRQLEEFKRTHFNEDELANAMKSLKIQNKYEEDVAREKDHRFFNRIAGIDFDYKTMKETLQLLLTKLPKTDYKLPLISYSLSNTNNGGEITKFLLDHMSLKDIDQAETFGQDLLNLGFLKYCNGVGNTFVNSKKFQYQWKNTAYMFANVPMPGSEEPTTGESLISRFNNWDGSSAKEIIQSKIGNDQGAAKIQAPHISDNERTLFRMMDALAASDKKYYQECFKMDALRCSVEELLIDHLSFMEKCESDRLNAIKKATLDFCSTLGNKISSLRLCIDKMLTLENDIDPTADLLQLLVKYKTGSFKPQAIVYNNYYNPGSFQNFG----------VDLETRCRLDKKVVP------------------LIISSIFSYMDKIYPDLPNDKVRTSIWTDSVKLSLTHQLRNLLNKQQFHNEGEIFDILSTSKLEPSTIASVVKIYLLELPDP-----LIPNDVSDILRVLYLDYPPLVETALQNSTSSPENQQDDDNEEGFDTKRIRGLYTTLSSLSKPHIATLDAITTHFYRLIKILKMGENGNE--------VADEFTVSISQEFANCIIQSKITDDNEIGFKIFYDLLTHKKQIFHELKRQNSKN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * * ** .:. * : :::** .* . *. . :*: * * :*::*. * . . : :: :: : : .: *. *: :: :.. .**: : ..*. ::..:* * : *::: :. *:: .: * : * : :. : :: ::: * . :: . * . :: * :*:. :: . ... :. : . ::: : . * :: . . . .: :: * : : *. : :.. . : .: .::: . . :. : *. : . :. : ", "identical_positions": 35, "similar_positions": 126, "identity": "4.61%" }, { "cls_id": "homologset.agr.MGI:1321398", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JHY1-1", "uniprot_id": "JAM1_RAT", "id": "Q9JHY1-1", "name": "Junctional adhesion molecule A", "aln": "MGTEGKAGSKLLFLFT-SMILGSLVQGKGSVYSPQTAVQVPENDSVKLPCIYSG-F-SSPRVEWKFVQG-STTALVCYNNQITVPYADRVTFSSSGITFSSVTRKDNGEYTCMVSEDGGQNYGEVSIHLTVLVPPSKPTVSIPSSVTIGNRAVLTCSEHDGSPPSEYSWFKDGVPMLTADAKKTRAFINSSYTIDPKSGDLVFDPVSAFDSGEYYCEAQNGYGTAMRSEAVRMEAV--------------ELNVGGIVAAVLVTLILLGLLIFGIWFAYSRGYFERTKKG---TAPGKKVIYSQPSARSEGEFKQTSSFLV-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88792-1", "uniprot_id": "JAM1_MOUSE", "id": "O88792-1", "name": "Junctional adhesion molecule A", "aln": "MGTEGKAGRKLLFLFT-SMILGSLVQGKGSVYTAQSDVQVPENESIKLTCTYSG-F-SSPRVEWKFVQG-STTALVCYNSQITAPYADRVTFSSSGITFSSVTRKDNGEYTCMVSEEGGQNYGEVSIHLTVLVPPSKPTISVPSSVTIGNRAVLTCSEHDGSPPSEYSWFKDGISMLTADAKKTRAFMNSSFTIDPKSGDLIFDPVTAFDSGEYYCQAQNGYGTAMRSEAAHMDAV--------------ELNVGGIVAAVLVTLILLGLLIFGVWFAYSRGYFERTKKG---TAPGKKVIYSQPSTRSEGEFKQTSSFLV-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y624-1", "uniprot_id": "JAM1_HUMAN", "id": "Q9Y624-1", "name": "Junctional adhesion molecule A", "aln": "MGTKAQVERKLLCLFILAILLCSLALGSVTVHSSEPEVRIPENNPVKLSCAYSG-F-SSPRVEWKFDQG-DTTRLVCYNNKITASYEDRVTFLPTGITFKSVTREDTGTYTCMVSEEGGNSYGEVKVKLIVLVPPSKPTVNIPSSATIGNRAVLTCSEQDGSPPSEYTWFKDGIVMPTN-PKSTRAFSNSSYVLNPTTGELVFDPLSASDTGEYSCEARNGYGTPMTSNAVRMEAV--------------ERNVGVIVAAVLVTLILLGILVFGIWFAYSRGHFDRTKKG---TSS-KKVIYSQPSARSEGEFKQTSSFLV-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58JHH1-1", "uniprot_id": "A0AC58JHH1_DANRE", "id": "A0AC58JHH1-1", "name": "Junctional adhesion molecule A", "aln": "---------MLTFAFVCFSLFVTGIHGFQVTVTSP--VKVKENEGVDLQCSYTSDFGATPRVEWKFKDLKGSQTLVYFDGKPTGQYTGRVTMYDKGLRFNKVTRADTGDYDCEVSGSGG--YGENTIKLTVLVPPAKPVSRIPSSVTTSSNVRLTCFDPVGSPPSTYKWYKDNTPLPED-PTKFPAFKNLTYKMNVFNGNLEFPSVSKMDTGSYFCEASNGEGVPQRGDEVKMEVLMSSCRGPCRSSIQGDLNVGGIVAGVIVALLAVGLLLFGLWYASKKGYLPKNRNRKLFIHSLRQMMWMRLMDSDRNHLLWCSLCSSE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * :: : * . :. *:: **: :.* * *:. * ::******* : .: ** ::.: * * .***: .*: *..*** *.* * * ** .** *** .::* *****:**. :***.* .... *** : ***** *.*:**. : ... ** * :: :: .*:* * .:: *:*.* *:* ** *.. .: .:*:.: : *** ***.*:*:*: :*:*:**:*:* .:*:: :.:: . ::::: : ....: * ", "identical_positions": 96, "similar_positions": 100, "identity": "29.81%" }, { "cls_id": "homologset.agr.MGI:1321402", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8J8YIH6-1", "uniprot_id": "A0A8J8YIH6_RAT", "id": "A0A8J8YIH6-1", "name": "Lymphocyte cytosolic protein 2", "aln": "MALKNVPFRSEVLAWNPDNLADYFRKLNYRDCEKAVKKYHIDGARFLNLTENDIQKFPKLRMPILSKLSQDINKNEERRSIFTRKPPVPRYPEEIEIHEEDDGGWSSF-EDDYESPNDDDPDGEDDGDYESPNE-EEETLVDDAADYEPPPSNDEEALQNSILPAKPFPNTNSMYIDRPPTGKVSQQPPVPPQRPMAALPPLPTGRNHS------PNHEEPSRNRNHKTAKLPAPSIDRSTKPPLDRSLAPPLDREP-LLGKKP--SDKPSAPLGR---EHLPKIQKPPLPPAMDRHERNERIGPLTARKPPVPRHGRGPDRRDNVSVKLHQRPLPHPSLPSMSSNTFPSRSTKPSPKNTFPLPHMPGAISESNIGFQQSASLPSYFSQGPSSRPPVRNEVRNLPLPVPNRPQPPSPGEEESPLDEEWYVSYITRPEAEAALRKINQDGTFLVRDSSKKTVNNPYVLMVLYKDKVYNIQIRYQEESQVYLLGTGLRGKEDFLSVSDIIDYFRKMPLLLIDGKNRGS--RYQCTLTHAAGCL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60787-1", "uniprot_id": "LCP2_MOUSE", "id": "Q60787-1", "name": "Lymphocyte cytosolic protein 2", "aln": "MALKNVPFRSEVLAWNSDNLADYFRKLNYRDCEKAVKKYHIDGARFLNLTENDIQKFPKLRMPLLSKLSQDINKNEERRSIFTRKPQIPRFLEETESHEEDDGGWSSF-EDDYESPNDDDPDGEDDGDYESPNE-EEQALVDDAADYEPPPSNNEEALQSSILPPNSFHNTNSMYIDRPPTGKVSQQPPVPPLRPKPALPPLPTGRNHSPLSPPHPNHEEPSRSGNNKTAKLPAPSIDRSTKPPLDRSLAP-LDREPFILGKKPPFSDKPSAPLGR---EHLPKIQKPPLPPAMDRHERNERLGPVTTRKPPVPRHGRGPDRRENDEDDVHQRPLPQPSLPSMSSNTFPSRSVQPSSKNTFPLAHMPGAFSESNIGFQQSASLPPYFSQGPGNRPPLRSEGRNLPLPVPNRPQPPSPGEEETPLDEEWYVSYITRPEAEAALRKINQDGTFLVRDSSKKTANNPYVLMVLYKDKVYNIQIRYQEESQVYLLGTGLRGKEDFLSVSDIIDYFRKMPLLLIDGKNRGS--RYQCTLTHAAGCL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13094-1", "uniprot_id": "LCP2_HUMAN", "id": "Q13094-1", "name": "Lymphocyte cytosolic protein 2", "aln": "MALRNVPFRSEVLGWDPDSLADYFKKLNYKDCEKAVKKYHIDGARFLNLTENDIQKFPKLRVPILSKLSQEINKNEERRSIFTRKPQVPRFPEETESHEEDNGGWSSFEEDDYESPNDDQ-DGEDDGDYESPNE-EEEAPVEDDADYEPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQPPVPPQRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDRSLAP-FDREPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERS---SPLPGKKPPVPKHGWGPDRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKPSPMNPLPSSHMPGAFSESNSSFPQSASLPPYFSQGPSNRPPIRAEGRNFPLPLPNKPRPPSPAEEENSLNEEWYVSYITRPEAEAALRKINQDGTFLVRDSSKKTTTNPYVLMVLYKDKVYNIQIRYQKESQVYLLGTGLRGKEDFLSVSDIIDYFRKMPLLLIDGKNRGS--RYQCTLTHAAGYP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PZU9-1", "uniprot_id": "A0A8M9PZU9_DANRE", "id": "A0A8M9PZU9-1", "name": "", "aln": "---MNLPTKSEVMGWNSGNLADYLKRMKLVGCDRTVKKSNMSGARFLNMTDKDLKMFPTPHIPFITKICKDINQNNKEKKSLFHRSDHRKPPNQVEPTSG-GWDSDEFDQEDSDNDYEEPDNNEFEDNYICAASGDTAENVNSDDDYEAPPSERPSEIPTHFRAAKPMGDGD--YIDTCPRG--SARPP-----------------------------------QDNSSGRLPRGLLN-ISKPPSRPDPSP----------------QRPFIPPNQ--------AKPTPAVPTVDRSKKP---------------------------------------------GSSKKQTEKPAPKKNITMATKPATLPTQRFNMQQMDDFP----------------------PPPVEVNEKMEQICSQDMDPQWYVGQISRGEAEVSLRKVKKDGTFLVRDSSKGCEEQPYTLMVLHQQKVYNIQIRFLGNKDGYSLGTGLNGIENYSSVAEMIMHHMKNPLFLIDGLDRGAGAQNQCCLMHPAGY-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:* :***:.*:...****::::: .*:::*** ::.******:*::*:: **. ::*:::*:.::**:*::.:. : ::. : :: * . . . ..* ::* :. :: :.* :.:* .. . : *:. ***.***: . : . : ..:.: : : *** * * . :** ::.:.:** :: :*** . :* ::* * .: : .* *: :* :: .: .:: :*:. : :. . *.::. .. .: * .:* * * . . . :: :***. *:* ***.:***:::*********** :**.****:::********: :.: * *****.* *:: **:::* :. * **:**** :**: : ** * *.** ", "identical_positions": 127, "similar_positions": 163, "identity": "23.48%" }, { "cls_id": "homologset.agr.MGI:1321404", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZAS0-1", "uniprot_id": "D3ZAS0_RAT", "id": "D3ZAS0-1", "name": "", "aln": "MSGGGRTSEAFLWDLLIIGHTQSLTMNSVAAALLVWILTSPSSSDHGREKGWPTHMACSSGGLEVVYQSCDPFQDFGLSIDQCSKQIQPNLNIRFGIILREDIRKLFLDIAFVAKGSSLLNYSYPLCEEDQPKFSFCGRRKGEQIYYAGPVNNPGLDVPQGEYQLLLELYNENHATVACANATVTCS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88188-1", "uniprot_id": "LY86_MOUSE", "id": "O88188-1", "name": "Lymphocyte antigen 86", "aln": "-------------------------MNGVAAALLVWILTSPSSSDHGSENGWPKHTACNSGGLEVVYQSCDPLQDFGLSIDQCSKQIQSNLNIRFGIILRQDIRKLFLDITLMAKGSSILNYSYPLCEEDQPKFSFCGRRKGEQIYYAGPVNNPGLDVPQGEYQLLLELYNENRATVACANATVTSS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95711-1", "uniprot_id": "LY86_HUMAN", "id": "O95711-1", "name": "Lymphocyte antigen 86", "aln": "-------------------------MKGFTATLFLWTLIFPSCSGGGGGKAWPTHVVCSDSGLEVLYQSCDPLQDFGFSVEKCSKQLKSNINIRFGIILREDIKELFLDLALMSQGSSVLNFSYPICEAALPKFSFCGRRKGEQIYYAGPVNNPEFTIPQGEYQVLLELYTEKRSTVACANATIMCS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:..:*:*::* * **.*. * :.**.* .*...****:******:****:*:::****::.*:*********:**::****::::::***:**:***:** *********************** : :******:*****.*:::********: .*", "identical_positions": 102, "similar_positions": 47, "identity": "54.55%" }, { "cls_id": "homologset.agr.MGI:1328306", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q75PQ8-1", "uniprot_id": "ORC2_RAT", "id": "Q75PQ8-1", "name": "Origin recognition complex subunit 2", "aln": "-MSTLRLKEAKVPSVQFVGDDDVLSHILDR-------------EGGTKLKKEKVQLLVNPQKVIKKAECELEKSDLEVLEDQNYVEVLG--------RNIQESLGNG--SAVDGRNKVYSFQHRKHPEEMTKLALELAKTSGKIDPLAS-NDPKITKNIARKSKGHS-SEKAPLENNNKNEFPSIQPHNVRKRLIASRSHCDS--------------ESEYSASSSEDDEEVAKDDEEDTNVVRCSKKSQGQNRLLPAPVSKEILPKKRKRDKAGDLVEE---YFEAHSSSKVLTSDRTLQKLRRARVDQKTLRNLLSKFVPSFSTE--IGQLNQQHERLFDKWILQLRLGFNIVLYGLGSKRDLLEKFRTTMLQDSIH---------------------VVINGFFPGISVKSILNSITEDVLSHMGTFQS--------VLDQRDWIMNRFKEDSSLELFLLIHNLDSQMLRGDNSQQILGQLSSLRNVYLIASIDHLNAPLMWDHAKQSLYNWLWYETTTYSPYTEETSYENSLLVKQSGSLP-LSSLIHVLRSLTPNARGIFRLLMKYQLDNQD----------CPSYIGLSFQDFYQQCREAFLVNSDLTLRAQLTEFRDHKLIRTKKGTDGVEYLLIPVDSGTLADFLEKEEEEES", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60862-1", "uniprot_id": "ORC2_MOUSE", "id": "Q60862-1", "name": "Origin recognition complex subunit 2", "aln": "-MSTLQLKETKVPSVQFVGDDDVLSHILDR-------------EGGTKLKKEKAQLLVNPQKVIKKADCELEKSDLEVLEDQNYVKVLG--------RNIQESLGNG--SAKDGRNKVYSFQQRKHPEEMTKLALELAKTSGKKDPLDS-NDPEITKNIAQKSKGHSTSEKAPLVNNNKTEFLSTQPHNLRKRIIASRSHYDS--------------ESEYSASSSEDDEEATKDEEEDTNVARLSQKSQGQNRLLPAPVSKETLPKKKKRDKASDLVEE---YFEAHSSSKVLTSDRTLQRLRRARVDQKTLHNLLRKFVPSFSAE--IERLNQQHEKLFHKWMLQLHLGFNIVLYGLGSKRDLLEKFRTTMLQDSIH---------------------VVINGYFPGVSVKSILNSITEDVLSHVGTFQS--------VLDQRDWIINRFKEDSSLELFLLIHNLDSQMLRGDNSQQILGQLSSLHNVYLIASIDHLNAPLMWDHAKQSLYNWLWYETTTYSPYTEETSYENSLLVKQSGSLP-LSSLIHVLRSLTPNARGIFRLLMKFQLDNQD----------SPSYIGLSFQDFYQQCREAFLVNSDLTLRAQLTEFRDHKLIRTKKGTDGVEYLLIPVDSGILADFLEKEEEEA-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13416-1", "uniprot_id": "ORC2_HUMAN", "id": "Q13416-1", "name": "Origin recognition complex subunit 2", "aln": "-MSKPELKEDKMLEVHFVGDDDVLNHILDR-------------EGGAKLKKERAQLLVNPKKIIKKPEYDLEEDDQEVLKDQNYVEIMG--------RDVQESLKNG--SATGGGNKVYSFQNRKHSEKMAKLASELAKTPQKSVSFSLKNDPEITINVPQSSKGHSASDKVQPKNNDKSEFLSTAPRSLRKRLIVPRSHSDS--------------ESEYSASNSEDDEGVAQEHEEDTNAVIFSQKIQAQNRVVSAPVGKETPSKRMKRDKTSDLVEE---YFEAHSSSKVLTSDRTLQKLKRAKLDQQTLRNLLSKVSPSFSAE--LKQLNQQYEKLFHKWMLQLHLGFNIVLYGLGSKRDLLERFRTTMLQDSIH---------------------VVINGFFPGISVKSVLNSITEEVLDHMGTFRS--------ILDQLDWIVNKFKEDSSLELFLLIHNLDSQMLRGEKSQQIIGQLSSLHNIYLIASIDHLNAPLMWDHAKQSLFNWLWYETTTYSPYTEETSYENSLLVKQSGSLP-LSSLTHVLRSLTPNARGIFRLLIKYQLDNQD----------NPSYIGLSFQDFYQQCREAFLVNSDLTLRAQLTEFRDHKLIRTKKGTDGVEYLLIPVDNGTLTDFLEKEEEEA-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q24168-1", "uniprot_id": "ORC2_DROME", "id": "Q24168-1", "name": "Origin recognition complex subunit 2", "aln": "-MSASNKGGYKTPRKENLMSIENLTNSEEESEDLNTAMVGNAVESQPKVTSRRSTRRPSPTKKYQAYQKESNGKGQEERIVVNYVEMSDERSSDAEDQEEEESIEESENAARPAAKDLHLIQSEYNVAGTSMFGFNTPKKRDAMALAALNATPCTPKTPKTPRLGVKTPDTKRKKSMDQPKTPAHVRTRVKKQIAKIVADSDEDFSGDESDFRPSDEESSSSSSSSDAGNSSDNDAADDEPKTPSRARRAIVVPVLPKTPSAARLRQSARAKKSNEFVPESDGYFHSHASSKILTSDHTLDRLKNPRLAADRVFSLLSEIKTSAEHEGSINAIMEEYRSYFPKWMCILNEGFNILLYGLGSKHQLLQSFHREVLHKQTV---------------------LVVNGFFPSLTIKDMLDSITSDILDAGISPAN--------PHEAVDMIEEEFALIPETHLFLIVHNLDGAMLRNVKAQAILSRLARIPNIHLLASIDHINTPLLWDQGKLCSFNFSWWDCTTMLPYTNETAFENSLLVQNSGELA-LSSMRSVFSSLTTNSRGIYMLIVKYQLKNKG----------NATYQGMPFRDLYSSCREAFLVSSDLALRAQLTEFLDHKLVKSKRSVDGSEQLTIPIDGALLQQFLEEQEKK--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32833-1", "uniprot_id": "ORC2_YEAST", "id": "P32833-1", "name": "Origin recognition complex subunit 2", "aln": "MLNGEDFVEHNDILSSPAKSRNVTPKRVDP-------------HGERQLRRIHSSKKNLLERISLVGNERKNTSPDPALKPKTPSKAPRKR---GRPRKIQEELTDR--IKKDEKDTISSKKKRKLDKDTSGNVNEESKTSNNKQVMEKTGIKEKREREKIQVATTTYEDNVTPQTDDN--FVSNSPEPPEPATPSKKSLTTN---------------HDFTSPLKQIIMNNLKEYKDSTSPGKLTLSRNFTPTPVPK---NKKLYQTSETKSASSFLDTFEGYFDQR--KIVRTNAKSRHTMSMAPDVTREEFSLVSNFFNENFQKRPRQKLFEIQKKMFPQYWFELTQGFSLLFYGVGSKRNFLEEFAIDYLSPKIAYSQLAYENELQQNKPVNSIPCLILNGYNPSCNYRDVFKEITDLLVPAELTRSETKYWGNHVILQIQKMIDFYKNQPLDIKLILVVHNLDGPSIRKNTFQTMLSFLSVIRQIAIVASTDHIYAPLLWDNMKAQNYNFVFHDISNFEPSTVESTFQDVMKMGKSDTSSGAEGAKYVLQSLTVNSKKMYKLLIETQMQNMGNLSANTGPKRGTQRTGVELKLFNHLCAADFIASNEIALRSMLREFIEHKMANITKNNSGMEIIWVPYTYAELEKLLKTVLNTL-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. : . : : : .. :: : : : : . . : :. :*.: : . : : . : : .*. . :. . :: : . : . . ::. .: :: :. :. : . ..:..:: **. : . : *. :: . : . .*: :. . : : : . * :: * **.:::**:***:::*: * * . :::**: *. . :.::..**. :: : . : . * . .*:*::****. :* . * ::. *: : :: ::** **: :**:**: * :*: : : :. * * *::::: : : :*. . .. *: *** *:: :: *::: *:.* . . *: :: : * *:...:::**: * ** :**: . .:. .* * : :* . * .:*: : ", "identical_positions": 70, "similar_positions": 190, "identity": "10.59%" }, { "cls_id": "homologset.agr.MGI:1328307", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88512-1", "uniprot_id": "AP1G2_MOUSE", "id": "O88512-1", "name": "AP-1 complex subunit gamma-like 2", "aln": "----------------------------------------MVVHSLRLQDLIEEIRGAKTQAQEREVIQKECAQIRASFRDGDPLQ--RHRQLAKLLYVHMLGYPAHFGQMECLKLIASPRFTDKRVGYLGAMLLLDERHDSHLLITNSIKNDLSQGNQPVQGLALCTLSTMGSAEMCRDLAPEVEKLLLQP-SPYVRKKAILTAVHMIRKDPELSGIFLPPCTKLLRERH----HGIQLGTVTLITELCERNPAALRHFRK-----------------VVPQLVQILRTLVTTGYSTEHSISGVSDPFLQVQILRLLRILGRNHEESS--------ETMNDLLAQVATNTDTSRNAGNAVLLETVLTIMAIHSAAGLRVLAVNILGRFLLNNDKNIRYVALTSLLQLVQSDHSAVQRHRSTVVECLQETDASLSRRALELSLALVNSSNVRAMMQELQAFLESCPPDLRADCASGILLAAERFAP----SKRWHIDTILHVLTTAGAHVRDDAVANLTQLIG-EAEELHTYSVRRLYSALAED-------ISQQPLVQVAAWCIGEYGDLLLEGNCEETEPFQVEEEDVLALLEKVLQSHMSLPATRGYAITALMKLSTRLRGDN--NRIRQVVSIYGSCVDLELQQRAVEYNTLFQKYDHMRAAILEKMPLVERGDP---HVKEG------------------------------------------------------------GKEKQTEAQPLEVTAPAPTEPQATKLLDLLDLLGDTSEPLSSGHA------------------------------------------QHLPPQTPSPGEALIHLLDLPCTPPPPAP-------------------------------------IPSVRVFEREGLQLDLSFMRPLETPALLLVTATTTNSSKEDVTHFVCQAAVPKSFQLQLQAPSGNTIPAQGGLPITQVFRILNPNQAPLRLKLRLTYNHSGQPVQEIFEVDNLPVETWQ--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75843-1", "uniprot_id": "AP1G2_HUMAN", "id": "O75843-1", "name": "AP-1 complex subunit gamma-like 2", "aln": "----------------------------------------MVVPSLKLQDLIEEIRGAKTQAQEREVIQKECAHIRASFRDGDPVH--RHRQLAKLLYVHMLGYPAHFGQMECLKLIASSRFTDKRVGYLGAMLLLDERHDAHLLITNSIKNDLSQGIQPVQGLALCTLSTMGSAEMCRDLAPEVEKLLLQP-SPYVRKKAILTAVHMIRKVPELSSVFLPPCAQLLHERH----HGILLGTITLITELCERSPAALRHFRK-----------------VVPQLVHILRTLVTMGYSTEHSISGVSDPFLQVQILRLLRILGRNHEESS--------ETMNDLLAQVATNTDTSRNAGNAVLFETVLTIMDIRSAAGLRVLAVNILGRFLLNSDRNIRYVALTSLLRLVQSDHSAVQRHRPTVVECLRETDASLSRRALELSLALVNSSNVRAMMQELQAFLESCPPDLRADCASGILLAAERFAP----TKRWHIDTILHVLTTAGTHVRDDAVANLTQLIG-GAQELHAYSVRRLYNALAED-------ISQQPLVQVAAWCIGEYGDLLLAGNCEEIEPLQVDEEEVLALLEKVLQSHMSLPATRGYALTALMKLSTRLCGDN--NRIRQVVSIYGSCLDVELQQRAVEYDTLFRKYDHMRAAILEKMPLVERDGP---QADEE------------------------------------------------------------AKE-SKEAAQLSEAAPVPTEPQASQLLDLLDLLDG-----ASGDV------------------------------------------QHPPHLDPSPGGALVHLLDLPCVPPPPAP-------------------------------------IPDLKVFEREGVQLNLSFIRPPENPALLLITITATNFSEGDVTHFICQAAVPKSLQLQLQAPSGNTVPARGGLPITQLFRILNPNKAPLRLKLRLTYDHFHQSVQEIFEVNNLPVESWQ--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0R024-1", "uniprot_id": "B0R024_DANRE", "id": "B0R024-1", "name": "AP-1 complex subunit gamma", "aln": "-----------------------------------------MTPSVRLQEMIRVIRSARTQGEERGIIQKECAEIRAQFRQTDNGE--RSHSLAKLLYVHMLGYPAHFGQMECVRLIASPRYSEKRIGYLGAMMLLDEKQDASLLITNSIKNDLSHSSQYVQSLALCTLACMGSSEMCRDLAPEIERLLRAS-TSYIKKKATLCAVHIIRKVPELAELFTPSARSLLSEKN----HGVLHGAVVLITELCERNAETLDKFRK-----------------AVPELVTIMKGLVTSSYSPEHNVAGISDPFLQVRILRLLRILGHNNDSAS--------DAMNDLLAQVATNTDSSKTAGSAVLYETVLTIMDINSESGLRVLAVNILGRFLLNNDRNIRYISMTSLQKIVQTDHNAVQRHRGTIVDCLKDQDTSVKRRALELSLALVSPVNIRSMMKELLIFLSSCPVELRSQTASGIFNAAERYSP----SKRWHIDTILHVLTTAGGDVRDETVPNLIQLIT-TASELHCYTVHKLYRALVKD-------ISQQSLVQVACWCIGEYGDLLLKGECEEIEPVQVTEDDVLDALETVLQSHMSAPATRGFALTATMKLSTRITDNV--DRIRSIVSIYGSCIDLELQQRAVEYNALFKKYDHMRAAVLERMPLMEKNSPGHTNGDSS------------------------------------------------------------GEIKEPEPAKTKPVEPILLSEPANQVCDLLDLLGG----TDTPVQ------------------------------------------PSSAPTSTATTTSSADLLDLLGG-LEPTP-------------------------------------VPAVTVYEKNGVSLKIQCDS--QTDTDITVTLIASNSTQNDISNFTLQAAVPKSVQLQMKAPSGNVIAAHGLGQVTQTVLLNNPNKVSLKMRVRVSYSDQGTMLQDTVQIDSFPSPSWNSQPSIGVL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7KVR8-1", "uniprot_id": "Q7KVR8_DROME", "id": "Q7KVR8-1", "name": "AP-1 complex subunit gamma", "aln": "MYPYYEQDWSVLPPENNRRFNPAFNMATIRQAFTEAVERVRMPTPTRLRDLIRQIRAARTAAEERAVVNKECAYIRSTFREEDSVW--RCRNIAKLLYIHMLGYPAHFGQLECLKLTASTRFTDKRIGYLGAMLLLDERQDVHLLITNCLKNDLNSSTQFVVGLALCTLGAIASPEMARDLASEVERLMKSP-NTYIRKKATLCAFRVIRRVPELMEIFLPATRSLLSEKN----HGILITGVTLITEMCENSSDTLMHFKKD-----------SGNREIVPNLVRILKNLILGGYSPEHDVSGVSDPFLQVKILRLLRILGHNDPDAS--------EAMNDILAQVATNTETSKNVGNTILYETVLSIMDIRSEGGLRVLAVNILGRFLLNSDKNIRYVALNTLLRTVHADTSAVQRHRTTILECLKDPDVSIRRRAMELSFALINAQNIRTMTKELLLFLEKADAEFKAQCSSGMILAAERYSP----TTRWHLDTQLSVLIAAGNYVRDDVVSSTIQLVSSSPVPEQTYITNRFWESLQVANH----CEDKQPLLQVAVWAIGEYGDLFMYG-ANEDEFERPTESDLIAVYYKFLTSAQVSTTSKQYALVSLAKLSTRLQQCV--EEIQALITSFGSHLNVDLQQRGVEFTQLFGHYKHLRPPLLEKMPAMQISRISSQNGESGGGSFDDNSPDVIENGVEGGGGGGHSLIESNMNTLGDNTNILLDLLGSTDLSAGGAGDLVAATDLSNAVHKKNSRNANDVVAPVSNNQDLLDLLDLDLSAPSSTTTGAPAGGGGGGGIVALVGDNNQSSAANMNNMLGGLDLGGFGSGLDSSASIPTNGNDLASMLGGLGAPPAASPSLAASAPVGNLIDGHAGSLLADLNPTAASNNVVVPPQGPRLTALDKDGLLVQLVSVR---GSDCMRIYMTTTNNSDNTLDQYLLQAAVQRSFQLQMLTPSGSVLPPGG--VITQEMRVVATSNATLRMRLRIQYVLDGQQQVEQTEVSGFPEQQPAPAAAE---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12028-1", "uniprot_id": "AP1G1_YEAST", "id": "Q12028-1", "name": "AP-1 complex subunit gamma-1", "aln": "-------------------------------------------MGSSLRSFIKDVRGAKTLADERAIITKQSAKIRTKLRDDHLPHEKRRVNIQKLLYLYILGEKTHFGQVESINLIASDDFVDKRLGYLAATLLLDESEDLLTLLTNMLNNDLHHPNKYAVSLALTSLGFLSSPELARDLYPDVENIIKNSRDPFLLKKALQCAAKLIFKDVSLLEIFNIEDITKILSSHSICTHGVLLGVTKIIQSILLIGLNRKKDEDEDEDGIDYSNDILSPLSLLLRDFFIRLENMNSKNIEPGYDVQGICDPFLQCEIIYTLKLYFQVGELLNSNNVLDYKDNFCDLLTRIATNTDSTKNSGQAILYETVKTIFSLDLNQPLRVLGINILAKFLAGKDNNTKYVSLNTLLKVVPQEPTAVQRHRKFISHCLQDTDVSIRMRALELSFAILDDSNLVELVNELMKFLAKQDEDSKDLIIYTIDHLIDTFDTRVVKDESWKLDVFFNILKLVGSFINYEKINDILIIINNTSQLSDKSEFLRKMLTISLNGTSAEISEENIGWQLVLIWCIGEYGDLVLNEGNKNGADIINESSITDYLLTLQELYTATNLKIINYILTAALKLSVRFHDAKNIEKLRQLILSYTDSTDLSLQMKSNQYEIFFNQSISVKKIILETMPKFEKITEEQDNGKALSKN------------------------------------------------------LISNEPVDLLSDLLGEDSKAESKASTGDNVKPIDILEEIFGEKNDIAQ---------------------------------------------VPKNANKEESINHSSAVEANSGVTLP-------------------------------------LDANKIYDSSSLNVYASLLS----ANSGLAHLDLYFQAKSLISDLKTFCAVPKAQKLTLGQLYPSST-INASQICKQSLKISGSGKLKLRVKLDFHLNGSSSITNEQFDHKFDETL-----------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "D3ZGW2-1", "uniprot_id": "D3ZGW2_RAT", "id": "D3ZGW2-1", "name": "Junctophilin", "aln": "---------------------------------------------MSPGGKFDFDDGGCYVGGWEAGRAHGYGVCTGPGAQGEYSG-CWAHGFESLGVFTGPGGHSYQGHWQQGKREGLGVERKSRWTYRGEWLGGLKGRSGVWESVSGLRYAGLWKDGFQDGYGTETYSDGGTYQGQWQAGKRHGYGVRQS-VPYHQAALLRSPRRTSLDSGHSDPPTPPPPLPLPGDEG-----GSPASGSRGGFVLAGPGD--------------------------------------ADGASSRKRTPAAGGFFRRSLLLSGLRAGGRRSSLGS---------KRGSLRSEVSSEVGSTGPPGSEASGPPIPAPPALIEGSATEVYAGEWRADRRSGYGVSQRSNGLRYEGEWLGNRRHGYG--RTTRPDGSREEGKYKRNR-------LVHGGRVRSLLPLALRRGKVKEKVDRAVEGARRAVSAARQRQ---------------------EIAAARAADALLKAVAASSVAEKAVEAARMAKLIAQD---------LQPMLEAPGRRPRQD---------SGGSDTEPLDEDSPGVYENGLTPSEGSPELP------------------------------SSPASSHQPWRAPPCRSPLPPGGNWGPFSSPKAWPEEWGGPG-----------------------------------------------------------------------EQAEELAGYEAEDEAGMQGPGPRDGSPLLGGCSDSSGSLRE-----------------------------------------------EEGEDEESLPQLRAPGGSESEPVT-------------------------------------------------------------TPVLRGLSSRGPDAGCLTEEFEEPAATERPAQPGAANP------------------LVVGAVALLDLSLAFLFSQLLT-------------------------", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .. . . : . : . : .* . * :: *: : . . ..* * . : : .. .. :. . . : . .: : : : . .: . : . * : . . .. . . * : :: *: : . .: :.::::. :: *. .: : : .* . : . . . . : .: . : . * . :: . * :: .: : : : . . : : . : . .. . . :. : : . . :* . . : . .*. :. : : * : : . ", "identical_positions": 15, "similar_positions": 128, "identity": "1.46%" }, { "cls_id": "homologset.agr.MGI:1328308", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z0K6-1", "uniprot_id": "SCRG1_RAT", "id": "Q9Z0K6-1", "name": "Scrapie-responsive protein 1", "aln": "MMKCVVLVILGLTLLLGTQAMPSSRLSCYRKLLKDRNCHNLPEGRADLKLIDENVQHHFWEGKGCEMICYCNFSELLCCPKDVFFGPKISFVIPCNSH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88745-1", "uniprot_id": "SCRG1_MOUSE", "id": "O88745-1", "name": "Scrapie-responsive protein 1", "aln": "MMKSVVLVILGLTLLLETQAMPSSRLSCYRKLLKDRNCHNLPEGRADLKLIDANVQHHFWDGKGCEMICYCNFSELLCCPKDVFFGPKISFVIPCNNH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75711-1", "uniprot_id": "SCRG1_HUMAN", "id": "O75711-1", "name": "Scrapie-responsive protein 1", "aln": "MKLMVLVFTIGLTLLLGVQAMPANRLSCYRKILKDHNCHNLPEGVADLTQIDVNVQDHFWDGKGCEMICYCNFSELLCCPKDVFFGPKISFVIPCNNQ", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* *::. :****** .****:.*******:***:******** ***. ** ***.***:***********************************.:", "identical_positions": 76, "similar_positions": 14, "identity": "77.55%" }, { "cls_id": "homologset.agr.MGI:1328310", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0L6W0-1", "uniprot_id": "A0ABK0L6W0_RAT", "id": "A0ABK0L6W0-1", "name": "", "aln": "MHLKSTSQTLMERQKRKADIEKGLQFIQSTLPLKQEE-YEAFLLKLVQNLFAEGNDLFREKDYKQALVQYMEGLNVADYAASDQVALPRELLCKLYVNRAACYFTMGLYEKALEDSEKALGLDGESIRALFRKARALNELGRHKEAYECSSRCSLALPHDENVTQLGQELAQKLGLRVRKAYKRPQELETFS-LLSNGAPAGLTDQGTSNGLGSIDDIETDCYVDLRGSPALLPSTPTMPLFPHV--LDLLAPLDGSSRPLPSTEGLDDFSDGDVFGPELDTLLDSLSLVQGGLPGSGMPSELPQLIPVFPGGTPLLPPVVGGSIPVSSP------LPPASFGLVMDPSRKLAASVLDALDSPGPTLDPLDLLPYSEARLDALDSFG---------SARGSLDKP--DSFLEEAS-----SQDHRPPSS-TQKPAPSPEPSMPNTALLIKNPLAATHEFKQACQLCYPKTGPRAGDYTYREGLEHKCRRDVLLGRLRSSENQIWKRIRPRPTKTSFVGSYYLCKDMINKQDCKYGDNCTFAYHQEEIDVWTEERKGTLNRDLLFDPLGGVKRGSLTIAKLLKEHQGIFTFLCEICFDSKPRIISKGTKDSPSVCSNLAAKHSFYNNKCLVHIVRSTSLKYSKIRQFQEHFQFDVCRHEVRYGCLREDSCHFAHSFIELKVWLLQQYSGMTHEDIVQESKKYWQQMEAHAGKASSGLGTPRTHGPSS---------------------------------------FDLQMKFVCGQCWRNGQVVEPDKDLKYCSAKARHCWTKERRVLLVMSKAKRKWVSVRPLPSIRNFPQQYDLCIHAQNGRKCQYVGNCSFAHSPEERDMWTFMKENKILDMQQTYDMWLKKHNPGKPGEGTPISSREGEKQIQMPTDYAD-IMMGYHCWLCGKNSNSKKQWQQHIQSEKHKEKVFTSD--SDASGWAYRFPMGEFRLCDRLQKGKVCPDGDKCRCAHGQEELNEWLDRREVLKQKLAKARKDMLLCPRDDDFGKYNFLLQEDGDTTGATPEATVAATATAATTTTGE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F8VPP8-1", "uniprot_id": "F8VPP8_MOUSE", "id": "F8VPP8-1", "name": "", "aln": "----------MERQKRKADIEKGLQFIQSTLPLKQEE-YEAFLLKLVQNLFAEGNDLFREKDYKQALVQYMEGLNVADYAASDQVALPRELLCKLHVNRAACYFTMGLYEKALEDSEKALGLDGESIRALFRKARALNELGRHKEAYECSSRCSLALPHDENVTQLGQELAQKLGLRVRKAYKRPQELETFS-LLSNGAPAGLTDQGTSNGLGSIDDIETDCYVDLRGSPALLPSTPTMPLFPHV--LDLLAPLDGSSRTLPGTEGLDDFSDGDVFGPELDTLLDSLSLVQGGLPGSGMPSELPQLIPVFPGGTPLLPPVVGGSIPVSSP------LPPASFGLVMDPSRKLAASVLDALDSPGPTLDPLDLLPYSEARLGALDSFG---------SARGSLDKP--DSFLEETS-----SQDHRPPSS-TQKPAPSPEPSMPNTTLLIKNPLAATHEFKQACQLCYPKTGPRAGDYTYREGLEHKCRRDVLLGRLRSSENQIWKRIRPRPTKTSFVGSYYLCKDMINKQDCKYGDNCTFAYHQEEIDVWTEERKGTLNRDLLFDPLGGVKRGSLTIAKLLKEHQGIFTFLCEICFDSKPRIISKGTKDSPSVCSNLAAKHSFYNNKCLVHIVRSTSLKYSKIRQFQEHFQFDVCRHEVRYGCLREDSCHFAHSFIELKVWLLQQYSGMTHEDIVQESKKYWQQMEAHAGKASSGLGAPRTHGPST---------------------------------------FDLQMKFVCGQCWRNGQVVEPDKDLKYCSAKARHCWTKERRVLLVMSKAKRKWVSVRPLPSIRNFPQQYDLCIHAQNGRKCQYVGNCSFAHSPEERDMWTFMKENKILDMQQTYDMWLKKHNPGKPGEGTPISSREGEKQIQMPTDYAD-IMMGYHCWLCGKNSNSKKQWQQHIQSEKHKEKVFTSD--SDASGWAYRFPMGEFRLCDRLQKGKACPDGDKCRCAHGQEELNEWLDRREVLKQKLAKARKDMLLCPRDDDFGKYNFLLQEDGDTTGATPDAPVAATATAATTTTGE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UGR2-1", "uniprot_id": "Z3H7B_HUMAN", "id": "Q9UGR2-1", "name": "Zinc finger CCCH domain-containing protein 7B", "aln": "----------MERQKRKADIEKGLQFIQSTLPLKQEE-YEAFLLKLVQNLFAEGNDLFREKDYKQALVQYMEGLNVADYAASDQVALPRELLCKLHVNRAACYFTMGLYEKALEDSEKALGLDSESIRALFRKARALNELGRHKEAYECSSRCSLALPHDESVTQLGQELAQKLGLRVRKAYKRPQELETFS-LLSNGTAAGVADQGTSNGLGSIDDIETDCYVDPRGSPALLPSTPTMPLFPHV--LDLLAPLD-SSRTLPSTDSLDDFSDGDVFGPELDTLLDSLSLVQGGLSGSGVPSELPQLIPVFPGGTPLLPPVVGGSIPVSSP------LPPASFGLVMDPSKKLAASVLDALDPPGPTLDPLDLLPYSETRLDALDSFG---------STRGSLDKP--DSFMEETN-----SQDHRPPSG-AQKPAPSPEPCMPNTALLIKNPLAATHEFKQACQLCYPKTGPRAGDYTYREGLEHKCKRDILLGRLRSSEDQTWKRIRPRPTKTSFVGSYYLCKDMINKQDCKYGDNCTFAYHQEEIDVWTEERKGTLNRDLLFDPLGGVKRGSLTIAKLLKEHQGIFTFLCEICFDSKPRIISKGTKDSPSVCSNLAAKHSFYNNKCLVHIVRSTSLKYSKIRQFQEHFQFDVCRHEVRYGCLREDSCHFAHSFIELKVWLLQQYSGMTHEDIVQESKKYWQQMEAHAGKASSSMGAPRTHGPST---------------------------------------FDLQMKFVCGQCWRNGQVVEPDKDLKYCSAKARHCWTKERRVLLVMSKAKRKWVSVRPLPSIRNFPQQYDLCIHAQNGRKCQYVGNCSFAHSPEERDMWTFMKENKILDMQQTYDMWLKKHNPGKPGEGTPISSREGEKQIQMPTDYAD-IMMGYHCWLCGKNSNSKKQWQQHIQSEKHKEKVFTSD--SDASGWAFRFPMGEFRLCDRLQKGKACPDGDKCRCAHGQEELNEWLDRREVLKQKLAKARKDMLLCPRDDDFGKYNFLLQEDGDLAGATPEAP----AAAATATTGE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B6Z8-1", "uniprot_id": "A0ACD6B6Z8_DANRE", "id": "A0ACD6B6Z8-1", "name": "", "aln": "--------MDLERQKRKEEIQKALGFIQSSLPFPEPEGYEAFLTQLVCNLLDEGNAVYRDGEWRQAAVHYSEGVNVARYAQSEALVIPPELLESLYVNRAAAHYSLGEYERGVQDCDSALCVSEGSRRALYRKALCLRDQGRFREAYECGTGCLLTAPHDRQVSELAQDLANKLGLKIRKAYVSPQLDSTTSGTDNNGETNSPTGETSSNGLETLNDIGSDLTS-AQCIPAPLATPIPVSDDPQIPSLDPVEPQDMPESPSQEPSGRVPYS-------------VPVSEHMGECVMNEDTSCLDTLLESIPKGAEVSVNPVQGAIPTNLPNTAVGLRPPYSPGLPG-STPQLAAQFFNSAVSPLPPLEPFTALGQSEASSQTMESLGSFSSGAADTAGKGSLITGGLDSLSEYTLPGGRISHCFIPGLR-NHNAANANGPVGTNLSLLSRNPLAATHEFRQACNACYSRIGPRVMDYHYQPEAAHRCKRDVLLCRLKTADDPIWKRVRPRPARNNFLGAFVLCKEVQERQECQYGENCTFAYCQEEIDVWTQERKGALSRELLFDPLGTNERRALSVTRLLQLHMGMFMFLCEECFDSKPRIISKRSKENLAVCSNLTARHPFDDNKCLVHVVRSANVRYSKIRPLHPLCQFDVCRHEVRYGCQREDSCSFAHSVIELKCWVLQQDTGITHEEMVQESKRHWHRLEQNAQRQKPMPGPHQPSGSSSGGISGSSVVSGGVVGGGGDGISGGGGGGGGLVGCGRGRGLNLKMKFVCGQCWREGQVNEPDKSLKYCTAKARHSWTKERRVLLVKSFEKKKWVVVRPLPFSRTYPQQYDMCVHVMKQKKCHYIGNCSFAHSLEERDVWTYMKNNSLRDMQQMYEMWLSLTNQHRRADSNLMTPPPEEKQIAMPTDCSE-SMVG-------------------------------------------------------------------RRMSGGGGDL-----------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M3AXP6-1", "uniprot_id": "A0A8M3AXP6_DANRE", "id": "A0A8M3AXP6-1", "name": "", "aln": "--------MSAERQKRQEKIRRALSFIKSSLPYPDPQGYEGFVVQLVCDLLEEGNAVFAERDWMRALQHFSEAISVALYAENEELSVPSGLLESLYINRAVVHQNMGEFECAVKDCDRVLVICKDSAKALYRKAVCLKESGKLREALDCSTACLQASPQDQSVSSLSQEIAECLGLTHRKASSSSQRNKAAG-PEDECTAPSPSDEVSP---ASQQEKVSDSADDEWTSP-----------------VSPVSVSNSHDAPLCMSGG------------------VPQPLEDLELMGDELDLLLDCMTNDKDNTQTRVVPAGLACFSSSSPG-----LPPAFFSSAGSELNALDSFISPEPDSCSADLDALDSICPS-VGSGSVQLGG---------EGLDSLSHF---SLSDVKA-----CRSFLPSVKLTHSPQTRNGHVTSTLSSLSKNPLEPTHEFSQACSACFTSTGPGVLDFEFRSDVSHSCNKDLLLCRRRGGANSPWRRIRPRP-RNNFQGAFMLCREVLETRTCKYGEDCTFAYCPEEIEVWTQERRGLLIRELLFNPLPTNQKRALSVVELLKMHTGMFMFLCEACFDCKPRIISKRWKENPTLCANLKPQHQFDKKKCLVHALKGSSVSYSKIRTLNSRCVFDVCRQELSLACRKESGCIFAHSLMELQIWILQRETGISLDEIVQESIKHWNKQRPAVVASNSPNKTTTAAKSMSPIRVQETNGKARPAQETG-------------SAEVKRHRLELMLKFVCAQCWKDGLLSEPDRALKYCTAKVRHSWTKERRVLLVKSHERKKWVSVRPLPFAKTYPQQYDICAHVLKQRKCHYMGNCSFAHSQEEKDLWTYMKNNSLSDVQELFEVWLSTSNQGRASDNTSPPQPIEEKQITMPTDFAESMMEGFYCPLCGKHSNSERQWQRHISSEKHKQRVFSGEGEDESLAWTHRFPGRCFSICPRLDGG--CPEGVSCDFAHSEEELQEWCERRAFLRRRLNKARADMLISPTDNDFGNYNFLLQDETHTC---------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *****: .*.:.* **:*:** : : **.*: :** :*: *** :: : :: :* :: *.:.** ** .: : :* ** .*::***. : .:* :* .::*.: .* : * :**:*** .*.: *: :** :*.: * : *:*..*:.*.*::*: *** *** .* .: . .: . . :.: :. : :: :* * :. : : . . . . . . . * : ..:. . * ** . * : . . . *:.: : * . ::: * .** *: : .: . * :.. .. : * :*** .**** ***. *:. ** . *: :: * *.:*:** * : . : *:*:**** :..* *:: **::: : : *:**::***** ***:***:**:* * *:***:** :: :*::..**: * *:* **** ***.******* *:. ::*:** .:* * .:***** ::.:.: ***** :: *****:*: .* :*..* ****.:**: *:**: :*:: :::**** ::*:: . . .. . . . : ::* :****.***::* : ***: ****:**.**.********** * ::*** ***** :.:*****:* *. : :**:*:******** **:*:**:**:*.: *:*: :::**. * : .:.. . **** **** :: * * : . :* ", "identical_positions": 273, "similar_positions": 259, "identity": "25.73%" }, { "cls_id": "homologset.agr.MGI:1328311", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A6M0-1", "uniprot_id": "D4A6M0_RAT", "id": "D4A6M0-1", "name": "", "aln": "MSSTESPGRTSDKSPRQQVDRLLLGLRWQRLEEPLGFIKVLQWLFAIFAFGSCGSYSGETGALVRCNNDPKDVSSIIVLFGYPFRLYQVQYEMPLCDEESTSKTMNLMGDFSAPAEFFVTLGIFSFFYTMAALVIYLRFHKVYTENKRFPLVDFCVTVSFTFFWLVAAAAWGKGLTDVKGATRPSSLTAAMSVCHGEEAVCSAGATPSMGLANISVLFGFINFFLWAGNCWFVFKETPWHGQGQ--------DQGQGPSQESAAEQGAVEKQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O89104-1", "uniprot_id": "SYPL2_MOUSE", "id": "O89104-1", "name": "Synaptophysin-like protein 2", "aln": "MSSTESPGRTSDKSPRQQVDRLLLGLRWQRLEEPLGFIKVLQWLFAIFAFGSCGSYSGETGALVLCNNEAKDVSSIIVLFGYPFRLYQVQYEMPLCDQDSTSKTMNLMGDFSAPAEFFVTLGIFSFFYTMAALVIYLRFHKLYTENKRFPLVDFCVTVSFTFFWLVAAAAWGKGLTDVKGATRPSSLTAAMSVCHGEEAVCSAGATPSMGLANLSVLFGFINFFLWAGNCWFVFKETPWHGQGQ--------DQGQGPSQESAAEQGAVEKQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5VXT5-1", "uniprot_id": "SYPL2_HUMAN", "id": "Q5VXT5-1", "name": "Synaptophysin-like protein 2", "aln": "MSSTESAGRTADKSPRQQVDRLLVGLRWRRLEEPLGFIKVLQWLFAIFAFGSCGSYSGETGAMVRCNNEAKDVSSIIVAFGYPFRLHRIQYEMPLCDEESSSKTMHLMGDFSAPAEFFVTLGIFSFFYTMAALVIYLRFHNLYTENKRFPLVDFCVTVSFTFFWLVAAAAWGKGLTDVKGATRPSSLTAAMSVCHGEEAVCSAGATPSMGLANISVLFGFINFFLWAGNCWFVFKETPWHGQGQGQDQDQDQDQGQGPSQESAAEQGAVEKQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1Q7F9-1", "uniprot_id": "F1Q7F9_DANRE", "id": "F1Q7F9-1", "name": "", "aln": "---MEVVQKVMSG----------FSLDLGPVKEPLGFIRLLEWVFTICAFATTGGYVGSTVFTLKCPD--KDDVDVTANFGYPFRLPSHPYLINHCN--GSKNTTYLQGDFSSSAEFFVSIGVLGFLYCTFTLILYLGYQQVYRESNRGPIIDLVVTGIFAFLWLVCSSAWGKGLTDVKYATDPSRL---IILCLPEDK-CEIKSYPSVGRLNASVLFGFLNLILWAGNCWFIYKETPFHKPAN-------------PPVN--AEEGVSSS-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :. . ..* ::******::*:*:*:* **.: *.* *.* : * : ** .: . ******* * : *: .:.:* * ****:.*****::*::.*:* :*::** ::::* *.:* *::*: ** *:*:***.::********** ** ** * : :* *: *. : **:* * ******:*::********::****:* .: *. : **:*. .. ", "identical_positions": 105, "similar_positions": 72, "identity": "38.6%" }, { "cls_id": "homologset.agr.MGI:1328312", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q64305-1", "uniprot_id": "PTF1A_RAT", "id": "Q64305-1", "name": "Pancreas transcription factor 1 subunit alpha", "aln": "MDAVLLEHFPGALDTFPSSYFDEEDFFTDQSSRDPLEDGDELLGDEQAEVEFLSHQLHEYCYRDGACLLLQPAPSAAPHALAPPPLGDPGEPEDSGS--YCCDAGAPLGAFPYSPGSPPSCLAYPCT---AVLSPGTRLRGLNGAAAAAAAAARRRRRVRSEAELQQLRQAANVRERRRMQSINDAFEGLRSHIPTLPYEKRLSKVDTLRLAIGYINFLSELVQADLPLRGSGTGGCG---GPGGSRHLGGDSPGNQAQKVIICHRGTRSPSPSDPDYGLPPLAGHSLSWADEKQLKEQNIIRTAKVWTPEDPRKLNSKS-FDNIENEPPFEFVS--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QX98-1", "uniprot_id": "PTF1A_MOUSE", "id": "Q9QX98-1", "name": "Pancreas transcription factor 1 subunit alpha", "aln": "MDAVLLEHFPGGLDTFPSPYFDEEDFFTDQSSRDPLEDSDELLGDEQAEVEFLSHQLHEYCYRDGACLLLQPAPSAAPHALAPPPLGDPGEPEDNVS--YCCDAGAPLAAFPYSPGSPPSCLAYPCA---AVLSPGARLGGLNG--AAAAAAARRRRRVRSEAELQQLRQAANVRERRRMQSINDAFEGLRSHIPTLPYEKRLSKVDTLRLAIGYINFLSELVQADLPLRGSGAGGCG---GPGGSRHLGEDSPGNQAQKVIICHRGTRSPSPSDPDYGLPPLAGHSLSWTDEKQLKEQNIIRTAKVWTPEDPRKLNSKS-FDNIENEPPFEFVS--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7RTS3-1", "uniprot_id": "PTF1A_HUMAN", "id": "Q7RTS3-1", "name": "Pancreas transcription factor 1 subunit alpha", "aln": "MDAVLLEHFPGGLDAFPSSYFDEDDFFTDQSSRDPLEDGDELLADEQAEVEFLSHQLHEYCYRDGACLLLQPAPPAAPLALAPPSSGGLGEPDDGGGGGYCCETGAPPGGFPYSPGSPPSCLAYPCAG-AAVLSPGARLRGLSG---AAAAAARRRRRVRSEAELQQLRQAANVRERRRMQSINDAFEGLRSHIPTLPYEKRLSKVDTLRLAIGYINFLSELVQADLPLRGGGAGGCG---GPGGGGRLGGDSPGSQAQKVIICHRGTRSPSPSDPDYGLPPLAGHSLSWTDEKQLKEQNIIRTAKVWTPEDPRKLNSKSSFNNIENEPPFEFVS--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZSX3-1", "uniprot_id": "PTF1A_DANRE", "id": "Q7ZSX3-1", "name": "Pancreas transcription factor 1 subunit alpha", "aln": "MDTVL-DPFTG-LDSFSSSYFDDDDFFTDHSSRDHL-DTDDFLDED---VDFLTNQIQEY-YKD-------------------SRISQDGD---------YCDVGN----FSFS--SSSSTFSYGCADSTSELSP-HRDGGLLK----------RRRRMRSEVEMQQLRQAANVRERRRMQSINDAFEGLRSHIPTLPYEKRLSKVDTLRLAIGYINFLAELVQSDMPIRNPHS------------------DALNQPKKVIICHRGTRSPSPNDPDYGLPPLAGHSLSWTDEKQLKDQNIIRTAKVWTPEDPRKLHLKSSINNIENEPPFNFIS--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KFD8-1", "uniprot_id": "A0A0B4KFD8_DROME", "id": "A0A0B4KFD8-1", "name": "", "aln": "-------------------MFSMDNFDLEATMARHFFEGSQATNASTSSSDYFFGDEHSSESDD-------------------------------------------------EDDAYSSGFNSDQENTEKTFCPFSRRS-------------HKPRRLKCASQMAQQRQAANLRERRRMQSINEAFEGLRTHIPTLPYEKRLSKVDTLKLAISYITFLSEMVKKDKNGNEPGLSLQRNYQKEPPKKIILKDRTGGVAHSLSWYRKGDRYPGSKLYARTWTPEDPRGPHSQPLPLYNNSNSNQNQNSNQSSDDFSGSGADMSDPGAAASIFSSGSGM", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. ::* : : : : .: . ::: : :. * . : .* : :.* * : **::. :: * *****:**********:******:*****************:***.**.**:*:*: * . . . .:.: ::* * *... .* :. ::.* :. : ..* . . : . *. * ", "identical_positions": 65, "similar_positions": 65, "identity": "19.29%" }, { "cls_id": "homologset.agr.MGI:1328313", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O55229-1", "uniprot_id": "CHKB_MOUSE", "id": "O55229-1", "name": "Choline/ethanolamine kinase", "aln": "---------------------MAADGTGVVGGGAVGGGLPKDG-----LQDAKCP-EPIPNRRRASSLSRDAQRRAYQWCR---------------------EYLGGAWRRARPEE-LSVCPVSGGLSNLLFRCSLPNH------------------------------------------------------------------------------------VPSVGGEPREVLLRLYGAIL--QGVDSLVLESVMFAILAERSLGPQLYGVFPEGRLEQYLP-SRPLKTQELRDPVLSGAIATRMARFHG---MEMPFTKEPRWLFGTMERYLKQIQDLPSTSLP----------QMNLVEMYSLKDEMNSLRKLLDD----------------------------------------------TPSPVVFCHNDIQEGNILLLSE------------------------------------------------------------------PDSDDNLMLVDFEYSSYNYRGFDIGNHFCEWVYDYTYEEWPFYKARPTDYPTREQQLHFIRHYLAEVQKGEILSEEEQKKREEELLLEISRYSLASHFFWGLWSTLQASM------------------------------------------------STIEFGYLEYAQSRFQFYFQQKGQLTSSPSS-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O54783-1", "uniprot_id": "CHKB_RAT", "id": "O54783-1", "name": "Choline/ethanolamine kinase", "aln": "---------------------MAADGTGVVGGGAVGGPLSKDG-----LLDAKCP-EPIPNRRRSSSLSRDAQRRAYQWCR---------------------EYLGGAWRRARPEE-LSVCPVSGGLSNLLFRCSLPNH------------------------------------------------------------------------------------VPSMGGEPREVLLRLYGAIL--QGVDSLVLESVMFAILAERSLGPQLYGVFPEGRLEQYLP-SRPLKTQELRDPVLSGAIATKMARFHG---MEMPFTKEPRWLFGTMERYLKQIQDLPSTSLP----------QMNLVEMYSLKDEMNHLRTLLDA----------------------------------------------TPSPVVFCHNDIQEGNILLLSE------------------------------------------------------------------PDSDDNLMLVDFEYSSYNYRGFDIGNHFCEWVYDYTYEEWPFYKARPADYPTREQQLLFIRHYLAEVQKGEVLSEEEQKKQEEDLLIEISRYALASHFFWGLWSTLQASM------------------------------------------------STIEFGYLEYAQSRFQFYFQQKGQLTSFLSP-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y259-1", "uniprot_id": "CHKB_HUMAN", "id": "Q9Y259-1", "name": "Choline/ethanolamine kinase", "aln": "---------------------MAAEATAVAGSGAVGGCLAKDG-----LQQSKCP-DTTPKRRRASSLSRDAERRAYQWCR---------------------EYLGGAWRRVQPEE-LRVYPVSGGLSNLLFRCSLPDH------------------------------------------------------------------------------------LPSVGEEPREVLLRLYGAIL--QGVDSLVLESVMFAILAERSLGPQLYGVFPEGRLEQYIP-SRPLKTQELREPVLSAAIATKMAQFHG---MEMPFTKEPHWLFGTMERYLKQIQDLPPTGLP----------EMNLLEMYSLKDEMGNLRKLLES----------------------------------------------TPSPVVFCHNDIQEGNILLLSE------------------------------------------------------------------PENADSLMLVDFEYSSYNYRGFDIGNHFCEWVYDYTHEEWPFYKARPTDYPTQEQQLHFIRHYLAEAKKGETLSQEEQRKLEEDLLVEVSRYALASHFFWGLWSILQASM------------------------------------------------STIEFGYLDYAQSRFQFYFQQKGQLTSVHSSS----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8IMF4-1", "uniprot_id": "Q8IMF4_DROME", "id": "Q8IMF4-1", "name": "", "aln": "-----------------------MKQRNLRNNKALKRLQQPDNKNLNCCLSKRCNYENIWQHFNSNATLEEIRHAAARICR---------------------DYLTGPWKVVTPES-LVVKRISGGLSNFLYYVSLPDLNDYDELDEQKQQQEDIIGATATVTNRSGVFIHDDESAAKAVGVTLMARELINNDDVADAAPGATQAHKRQRCDSNSRECSSSKRLHAPKQQPREVLLRIYGQTHGDHALESMITESVVFALLSERNYGPKLHGIFPGGRIEQYIP-ARALTTAELGEQRILKRVAEKMGEIHS---LNIPMSKEPDWIWNCMQRWVSGLESIVNGSVQTNQKSSVLKKQMELMRTFDYVQEMAWIRSIIDE----------------------------------------------GDYPVVFCHNDLQEGNILMRQPSAGQNERTPRESISSLRSNFDETLGDSLDGNSNISDTETHKSRSVSPSPCPELDTTNDSALDSSFMADNEPDLIIIDFEYCAYNYRGYDLANHFIEWTFDYTNPQFPYFYHNSSNCATVQQRRDFIVNYLKKFHDDENYNITGQELMKVD--AEIQFFTMLSHLFWSLWSVINVT-------------------------------------------------SAIEFGYWEYGIARILEYQKLKAAYQAN--------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P20485-1", "uniprot_id": "KICH_YEAST", "id": "P20485-1", "name": "Choline kinase", "aln": "----MVQESRPGSVRSYSVGYQARSRSSSQRRHSLTRQRSSQRLIRTISIESDVSNITDDDDLRAVNEGVAGVQLDVSETANKGPRRASATDVTDSLGSTSSEYIEIPFVKETLDASLPSDYLKQDILNLIQSLKISKWYN--NKKIQPVAQDMNLVKISG--------------------------------------------------------AMTNAIFKVEYPKLPSLLLRIYGPNI--DNIIDREYELQILARLSLKNIGPSLYGCFVNGRFEQFLENSKTLTKDDIRNWKNSQRIARRMKELHVGVPLLSSERKNGSACWQKINQWLRTIEKVDQWVGDPKN----IENSLLCENWSKFMDIVDRYHKWLISQEQGIEQVNKNLIFCHNDAQYGNLLFTAPVMNTPSLYTAPSSTSLTSQSSSLFPSSSNVIVDDIINPPKQE---------------------------------------------------------------QSQDSKLVVIDFEYAGANPAAYDLANHLSEWMYDYNNAKAP-HQCHADRYPDKEQVLNFLYSYVSHLRGGAKEPIDEEVQRLYK---SIIQWRPTVQLFWSLWAILQSGKLEKK--EASTAITREEIGPNGKKYIIKTEPESPEEDFVENDDEPEAGVSIDTFDYMAYGRDKIAVFWGDLIGLGIITEEECKNFSSFKFLDTSYL-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q03764-1", "uniprot_id": "EKI1_YEAST", "id": "Q03764-1", "name": "Ethanolamine kinase", "aln": "MYTNYSLTSSDAMPRTYLVG-TASPEMSKKKRQSANCDKPTRRVIHIIDTN-EHSEVDLKNELPITCTNEDGEMTSSSWTS-----------------QTANDFLKLAYVNAKLDPSLPSQYFKQDIINVLQSLEIPGWSVPGSKESSLNKNLLTLTQIKG--------------------------------------------------------ALTNVIYKIHYPNLPPLLMRIFGDSI--DSVIDREYELKVIARLSFYDLGPKLEGFFENGRFEKYIEGSRTSTQADFIDRDTSIKIAKKLKELHCTVPLTHKEITDQPSCWTTFDQWIKLIDSHKEWVSNNVN----ISENLRCSSWNFFLKSFKNYKRWLYN---------------------------DSAFTSKLLREDDKDSMINSGLKMVFCHNDLQHGNLLFKSKGKD---------------------------------------------------------------DISVGDLTIIDFEYAGPNPVVFDLSNHLNEWMQDYNDVQS--FKSHIDKYPKEEDILVFAQSYINHMNENHVKIASQEVRILYN---LIIEWRPCTQLFWCLWALLQSGRLPQRPLIEGEKLMSEKAGLGDETHLMEHKNKENGKYDCSEDD---------SFNYLGFCKEKMSVFWGDLITLGVI-DKDCPDIGKTDYLDTKLIF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . ::: .: : * .. .: *.: .:. : :*:*::* . : . * ::* *: . **.* * * **:*::: ::. . :: : :* :: .:* : .: : ::::: ::. .: . . : : :* .. : :: . .* ::****.. * :*:.**: ** **. : . . . :: * *: . . . : . : : ::** **: :: *.* : :: : ", "identical_positions": 40, "similar_positions": 106, "identity": "5.56%" }, { "cls_id": "homologset.agr.MGI:1328314", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O89029-1", "uniprot_id": "MATN4_MOUSE", "id": "O89029-1", "name": "Matrilin-4", "aln": "MRGPCCWPLSLLLLFLQSWETQLQSAGPRCYNGPLDLVFMIDSSRSVRPFEFETMRQFLVGLLRSLDVGLNATRVGVIQYSSQVQSVFPLGAFSRREDMERAIRAVVPLAQGTMTGLAIQYAMNVAFSEAEGARPSEERVPRVLVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRTMASPPLDQHVFLVESFDLIQEFGLQFQGRLCGKDLCAELVHGCQHLCVNAPGTFYCACNSGYKLAPDNKNCLALDLCAEGTHGCEHLCVNSVDSYFCRCRAGFALQQDQRSCRAIDYCSFGNHSCQHECVSTLAGPQCRCREGHDLLPDGRSCRVRDFCNGVDHGCEFQCVSEGLSFHCLCPEGRRLQADGKSCDRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRDLNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEEELREIASEPSELHVSYSPDFSTMTHLLENLKGSICPEEGIGAGTELRSPCECESLVEFQGRTLGALESLTQNLARLTERLEELENQLASRK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZMS3-1", "uniprot_id": "D3ZMS3_RAT", "id": "D3ZMS3-1", "name": "Matrilin-4", "aln": "MKGPFCWPLPLLLLFLQSWETQLQPAGPRCYTGPLDLVFMIDSSRSVRPFEFETMRQFLVGLLHSLDVGLNATRVGVIQYSSQVQSVFPLGAFSNREDMERAIRAVVPLAQGTMTGLAIQYAMNVAFSEAEGARPSEERVPRVLVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDQHVFLVESFDLIQEFGLQFQGRLCGKDLCAELEHGCQHLCVNAPGTFYCACNSGYKLAPDNRNCLAIDLCAEGTHGCEHLCVSSVDSYFCRCRAGFALQQDQRSCRAIDYCSFGNHSCQHECVSTLVGPQCRCREGHDLLPDGRSCQVRDFCNGVDHGCEFQCVSEGLSFHCLCPEGRRLQADGKSCDRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEVQGARPRDLNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEEELREIASEPSELHVSYSPDFNTMTHLLENLKGSICPEEGISAGTELRSPCECESLVEFQGRTLGALESLTQNLARLTERLEELENQLASRK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O95460-1", "uniprot_id": "MATN4_HUMAN", "id": "O95460-1", "name": "Matrilin-4", "aln": "MRGLLCWP--VLLLLLQPWETQLQLTGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFGLQFQSRLCGKDQCAEGGHGCQHQCVNAWAMFHCTCNPGYKLAADNKSCLAIDLCAEGTHGCEHHCVNSPGSYFCHCQVGFVLQQDQRSCRAIDYCSFGNHSCQHECVSTPGGPRCHCREGHDLQPDGRSCQVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLENLRGSICPEEGISAGTELRSPCECESLVEFQGRTLGALESLTLNLAQLTARLEDLENQLANQK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:* *** :***:**.****** :****:.*******:*******************:***:.*:** ******************** ***.********* :********************** ******.******* ****************************************:*******:*******************.****** *** ***** **** . *:*:**.*****.**:.***:************ **.* .****:*:.**.**************************** **:*:******* ******:***:******************::*******:********:*****************************************************************************************************.****** ******************************************* *********:******:***.*********:*********.***************************** ***:** ***:******.:*", "identical_positions": 549, "similar_positions": 50, "identity": "87.98%" }, { "cls_id": "homologset.agr.MGI:1328315", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P59991-1", "uniprot_id": "KR122_HUMAN", "id": "P59991-1", "name": "Keratin-associated protein 12-2", "aln": "MCHTSCSSGCQPACCAPSPCQPACCVPSSCQASCCVPVGCQSSVCVPVSFKPAVCLPVSCQSSVCVPMSFKSAVCVPVSCQSSVCVPVSCRPIVCAAPSCQSSLCVPVSCRPVVYAAPSCQSSGCCQPSCTSVLCRPISYSISSCC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P60328-1", "uniprot_id": "KR123_HUMAN", "id": "P60328-1", "name": "Keratin-associated protein 12-3", "aln": "MCHTSCSPACQPTCCIHSPCQASCYVP--------------------------------------------------VSCQSSVCMPVSCTRIVCVAPSCQPSVCVPVSCRPIIYVTPSCQSSGCCQPPCTTALCRPISCSTPSCC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Z287-1", "uniprot_id": "KR121_MOUSE", "id": "Q9Z287-1", "name": "Keratin-associated protein 12-1", "aln": "MCHTSCSSGCQPSCCVSSSCQPSCCVSSPCQASCFVSSPCQPSCCVSSSCQSACCRP---------------AICIPVRYQVACCVPVSCGPTVCMAPSCQSSVCVPVSCRP-VCVTSSCQSSGCCQPSCPTLVCKPVTCSNPSCC", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*******..***:** *.**.:* *. * * : *:**** ** *****.*:******** : .:.**********.*.: :*:*:: * .***", "identical_positions": 57, "similar_positions": 23, "identity": "39.04%" }, { "cls_id": "homologset.agr.MGI:1328316", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6ALP3-1", "uniprot_id": "A0A8I6ALP3_RAT", "id": "A0A8I6ALP3-1", "name": "", "aln": "MGLRVMQLVSRVPSRLPKPQGAGSFRGAACRCWPAAAATRTWGRARGGDQVTRLLRLGSPRGRRAGKSQARVQEQGARPGGRPGQWRSAPVMSQGLQLLLLGCACSLAPALAMREVTVACSETADLPCTAPWDPQLSY-TVSWAKVSES-------GNERLELPES-----------KQNSSVEAPK------KRPYSLTIQNTTICSAGTYRCALQELGGQRNFSGTVVLKVTGCPKEATESTFRKYRAEAVLLFSLVVFYLTLIIFTCKFARLQSIFPDISKPGTEQAFLPVTSPSKHLGPVTLPKTETV-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88324-1", "uniprot_id": "CD83_MOUSE", "id": "O88324-1", "name": "CD83 antigen", "aln": "-------------------------------------------------------------------------------------------MSQGLQLLFLGCACSLAPAMAMREVTVACSETADLPCTAPWDPQLSY-AVSWAKVSES-------GTESVELPES-----------KQNSSFEAPR------RRAYSLTIQNTTICSSGTYRCALQELGGQRNLSGTVVLKVTGCPKEATESTFRKYRAEAVLLFSLVVFYLTLIIFTCKFARLQSIFPDISKPGTEQAFLPVTSPSKHLGPVTLPKTETV-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q01151-1", "uniprot_id": "CD83_HUMAN", "id": "Q01151-1", "name": "CD83 antigen", "aln": "-------------------------------------------------------------------------------------------MSRGLQLLLLSCAYSLAP--ATPEVKVACSEDVDLPCTAPWDPQVPY-TVSWVKLLEG-------GEERMETPQEDHLRGQHYHQKGQNGSFDAPN------ERPYSLKIRNTTSCNSGTYRCTLQDPDGQRNLSGKVILRVTGCPAQRKEETFKKYRAEIVLLLALVIFYLTLIIFTCKFARLQSIFPDFSKAGMERAFLPVTSPNKHLGLVTPHKTELV-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NEQ7-1", "uniprot_id": "A0A8M1NEQ7_DANRE", "id": "A0A8M1NEQ7-1", "name": "", "aln": "--------------------------------------------------------------------------------------------MRRFSELIVCLVTLVVAEDQLPEIRAIAGEDAVLRCSAKSETGVQYRSVIWYKVDEAEPSQQLTGLVRKRLTEDD----------GKVEKYNGVEREVVLLEDSKNLILSNVTAEDSGIYRCFLSAPLGYQNQRGDIILTVYKPQTVERMEFNKSSLVYLGEIAAIAGLFLGFLFFGISYVYIR----SFNQRGKKLSLLKMPSPGKNLITSNHLICKTLPEVYV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :. *:: . :.. *: . ..* . * *:* :. : * :* * *: *. * . .:. : . :. . . . .* : *.* .:* *** *. * :* * ::* * . :. . : ::. ::* :::* .:. :: .:.: * : ::* :.**.*:* . : : ", "identical_positions": 33, "similar_positions": 73, "identity": "10.41%" }, { "cls_id": "homologset.agr.MGI:1328317", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5BK16-1", "uniprot_id": "Q5BK16_RAT", "id": "Q5BK16-1", "name": "exodeoxyribonuclease III", "aln": "------MGSQALPHGHMQTLIFLDLEATGLPYSQPK---ITELCLLAVHRHALENSSMSEGQ--PPPVPKPPRVVDKLSLCIAPGKPCSSGASEITGLTTAGLEAHGRQRFNDNLATLLQVFLQRQPQPCCLVAHNGDRYDFPLLQAELASLSVISPLDGTFCVDSIAALKTLEQASSPSEHGPRKSYSLGSIYTRLYGQAPTDSHTAEGDVLALLSICQWKPQALLQWVDKHARPFSTIKPMYG---------MAATTGTASPRLCAATTSSPLATA-NLSPSNG-------RSRGKRPTSPPPENVPEAPSREGLLAPLGLLTFLTLAIAVLYGIFLASPGQ----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91XB0-1", "uniprot_id": "TREX1_MOUSE", "id": "Q91XB0-1", "name": "Three-prime repair exonuclease 1", "aln": "------MGSQTLPHGHMQTLIFLDLEATGLPSSRPE---VTELCLLAVHRRALENTSISQGH--PPPVPRPPRVVDKLSLCIAPGKACSPGASEITGLSKAELEVQGRQRFDDNLAILLRAFLQRQPQPCCLVAHNGDRYDFPLLQTELARLSTPSPLDGTFCVDSIAALKALEQASSPSGNGSRKSYSLGSIYTRLYWQAPTDSHTAEGDVLTLLSICQWKPQALLQWVDEHARPFSTVKPMYG---------TPATTGTTNLRPHAATATTPLATA-NGSPSNG-------RSR--RPKSPPPEKVPEAPSQEGLLAPLSLLTLLTLAIATLYGLFLASPGQ----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NSU2-3", "uniprot_id": "TREX1_HUMAN", "id": "Q9NSU2-3", "name": "Three-prime repair exonuclease 1", "aln": "------MGSQALPPGPMQTLIFFDMEATGLPFSQPK---VTELCLLAVHRCALESPPTSQGP--PPTVPPPPRVVDKLSLCVAPGKACSPAASEITGLSTAVLAAHGRQCFDDNLANLLLAFLRRQPQPWCLVAHNGDRYDFPLLQAELAMLGLTSALDGAFCVDSITALKALERASSPSEHGPRKSYSLGSIYTRLYGQSPPDSHTAEGDVLALLSICQWRPQALLRWVDAHARPFGTIRPMYG---------VTASARTK-PRPSAVTTTAHLATTRNTSPSLG-------ESR--GTKDLPPVKDPGALSREGLLAPLGLLAILTLAVATLYGLSLATPGE----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VQJ7-1", "uniprot_id": "Q9VQJ7_DROME", "id": "Q9VQJ7-1", "name": "Exonuclease domain-containing protein", "aln": "MAPNDAVAEHAEEQPKISTFAVLDLETTNLPAYRNNRVSITELCIYAFEAALLKKKKKEQDQDEQQELPAAPRVLHKLNVLFQPSMVVDPEAERITGLSNYLLERESQ--LDTDAAQLIVSFLKHLPSPVCLVAHNGWGFDFPILRQAFEKLNIELPQS-LTCVDSLRAFMEIDDTQQKETSQLKVPNDVQEIIPELKPKQNTETCLKEPEAVVNIDWRTRNETTPNRPILKPTEAFAKRKLLRDGDEDDLEEQTPPKRKPDEFRSRRQLFSGCKCAENKRYPPRGVYNLESLYTRIFKIPALSAHQAEADVVMTTKLIQHYGIDFLAFAEEQAIPFQQVVPLGSPVCRKKSAI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :..:: :.*: .:*:*:*.** : : :****: *.. *:. .:. :* .***:.**.: . *. .. *..****:. * ..: :: : * *: **:: *.* ******* :***:*: : *. . . ****: *: :: :.. . : . .: .* ..* : .:: * :.:. :. . : : : :..*.. : : . ... . * : .: : *. * :* .. : * : :*::* : . * ", "identical_positions": 60, "similar_positions": 111, "identity": "16.95%" }, { "cls_id": "homologset.agr.MGI:1328318", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CQD8-1", "uniprot_id": "VA0E1_MOUSE", "id": "Q9CQD8-1", "name": "V-type proton ATPase subunit e 1", "aln": "MAYHGLTVPLIVMSVFWGFVGLLVPWFIPKGPNRGVIITMLVTCSVCCYLFWLIAILAQLNPLFGPQLKNETIWYLKYHW--P----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q794C0-1", "uniprot_id": "VA0E1_RAT", "id": "Q794C0-1", "name": "V-type proton ATPase subunit e 1", "aln": "MAYHGLTVPLIVMSVFWGFVGLLVPWFIPKGPNRGVIITMLVTCSVCCYLFWLIAILAQLNPLFGPQLKNETIWYLKYHW--P----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O15342-1", "uniprot_id": "VA0E1_HUMAN", "id": "O15342-1", "name": "V-type proton ATPase subunit e 1", "aln": "MAYHGLTVPLIVMSVFWGFVGFLVPWFIPKGPNRGVIITMLVTCSVCCYLFWLIAILAQLNPLFGPQLKNETIWYLKYHW--P----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VZG7-1", "uniprot_id": "Q9VZG7_DROME", "id": "Q9VZG7-1", "name": "V-type proton ATPase subunit", "aln": "--M-EVFLTIVFFTIFWAAVAKYGPILFTKQPHDDLVRCIFLLTAVVCWLFWLCCYLAQLNPLLGPKLNGNTIRIIASSWGNPIKEG", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VZE9-1", "uniprot_id": "Q9VZE9_DROME", "id": "Q9VZE9-1", "name": "V-type proton ATPase subunit", "aln": "--MGAAFFPVLFFTALWGGVGIAMPIMTPKGPHQNLIRCILMLTAACCWLFWLCCYMAQMNPLIGPKLKRDVVAMIGRSWNNPIVAG", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q3E7B6-1", "uniprot_id": "VA0E_YEAST", "id": "Q3E7B6-1", "name": "V-type proton ATPase subunit e", "aln": "---MSSFYTVVGVFIVVSAMSVLFWIMAPKN-NQAVWRSTVILTLAMMFLMWAITFLCQLHPLVAPRRSDLRPEFAE----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:: . . . :. : .* : : .: . :*:* :.*::**..*: . ", "identical_positions": 7, "similar_positions": 25, "identity": "8.05%" }, { "cls_id": "homologset.agr.MGI:1328321", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9R224-1", "uniprot_id": "BEX1_MOUSE", "id": "Q9R224-1", "name": "Protein BEX1", "aln": "MESKDQGVKN-LNMENDHQKKEEKEEKPQDTIRREPAVALTSEAGKNCAPRGGRRRFRVRQPIAHYRWDLMQRVGEPQGRMREENVQRFGGDVRQLMEKLRERQLSHSLRAVSTDPPHHDHHDEFCLMP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q3MKQ2-1", "uniprot_id": "BEX1_RAT", "id": "Q3MKQ2-1", "name": "Protein BEX1", "aln": "MESKDQGAKN-LNMENDHQKKEEKEEKPQDTIKREPVVAPTFEAGKNCAPRGGRRRFRVRQPIAHYRWDLMHRVGEPQGRMREENVQRFGEDMRQLMEKLRERQLSHSLRAVSTDPPHHDHHDEFCLMP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9HBH7-1", "uniprot_id": "BEX1_HUMAN", "id": "Q9HBH7-1", "name": "Protein BEX1", "aln": "MESKEKRAVNSLSMENANQENEEK---EQVANKGEP-LALPLDAGEYCVPRGNRRRFRVRQPILQYRWDMMHRLGEPQARMREENMERIGEEVRQLMEKLREKQLSHSLRAVSTDPPHHDHHDEFCLMP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9BXY8-1", "uniprot_id": "BEX2_HUMAN", "id": "Q9BXY8-1", "name": "Protein BEX2", "aln": "MESKEERALNNLIVENVNQENDEKDEKEQVANKGEP-LALPLNVSEYCVPRGNRRRFRVRQPILQYRWDIMHRLGEPQARMREENMERIGEEVRQLMEKLREKQLSHSLRAVSTDPPHHDHHDEFCLMP", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****:: . * * :** :*:::** * : : ** :* . :..: *.***.********** :****:*:*:****.******::*:* ::*********:**************************", "identical_positions": 82, "similar_positions": 29, "identity": "63.57%" }, { "cls_id": "homologset.agr.MGI:1328322", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LZG2-1", "uniprot_id": "F1LZG2_RAT", "id": "F1LZG2-1", "name": "", "aln": "-------------------------------------------MSMALGNTLQGFLTFKDVVPEFTLEEWESLTYAQRALYMDVILETYNNLLSVENHLIHG--KHGEVLEQDTECIVHELVNIQEKFCKWDEISKMTLESTQSTPYKTHLRDPSLRSSNLKRHKAGKTREVYKYKDCVQFSNECAIIGVNSGIHIENKEHKNT----------------------EFDNDFVYKHKLMLKEDIN-----------------------------GKNLHQDGECEKCFTKTRKLHFYQRIHTGEKPYKCSECDKCFVSNLSLIIHQRIHTGEKPYKCSQCDKYFARESCLRRHQRSHSGEKPYKCSQCDKYFAQKYYLSIHQRIHTGEKRYKCSQCDKYFSQESCLRRHQRIHTGEKPYKCSQCDKYFSQKFHLSIHQRIHTGEKPYKCSECDKCFTEKRTLRNHMRIHTGEKPYKCSECDKCFGRKGSLRIHQRIHTGEKPYKCGECDKCFGQQSHRSIHQRIHTGEKPYKCSQCDKHFTQESCLRRHQRIHTGDKPYKCCQCDKYFSQEFYLSIHQRIHTGEKPYKCSECDKCFTEKGTLRNHMRLHTGEKPYKCSECDKSFVQQSHLTVHQRSHTGEKPYKCSQCDKCFARESCRRRHQRIHTGDKPYKCNQCAKYFAGESYLSIH------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6A734-1", "uniprot_id": "A0A8I6A734_RAT", "id": "A0A8I6A734-1", "name": "", "aln": "MYCICLVKRSRTSPTCQLLVFKPGCEISRKLPIFESVRRTAKRMSVALGNTLQGFLTFKDVAPEFTLEEWESLNYAQRALYMDVILETYNNLLSVENNLIGG--KHGNVLEQDTECIVHEHMNIQKNFCKWDEISKMTLESTQSTPYKTHLRDSSLQSSNLKRHRAGKMREIYKYKDCVQFSNECAILGVNSGIHIENKEHKNT----------------------EFDKEFVYKHKQMLKQDIN-----------------------------GKNLHQCSTCDKCFARKRNLHLHQRIHSAEKPYKCSQCDKYFAQQSCLMRHQRSHSGEKPYKCNQCDKFFAQVSHLSIHQRSHTGDKPYKCSECDKCYTQKGTLRSHMRIHTGEKPYKCDKCDKYFGRKSHLRVHQRIHTGDKPFKCSECDKRFTEKGPLRNHMGIHTGEKPFKCSKCDKCFVYKCSLRIHQRIHTGEKPYKCSQCDTYFARQYWLMCHQISHTREKPYKCNQCDKSFAQVSYLSIHQRIHTGDKPYKCSECDKCFRYKGSLKIHQRIHSGEKPYKCSECDKYFSQQANLSIHQRIHTGDKPYKCSECDKCFGYKGSLRIHQRVHTGDKPYKCSECDKCYTQKGTLRNHMRIHTGEKPYKCSECDKCFRYQSNLTIHRRIHIGDKPYKCSKCDKWFGHRVSLRIHQRICTGEKPNKCG-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6ABM4-1", "uniprot_id": "A0A8I6ABM4_RAT", "id": "A0A8I6ABM4-1", "name": "", "aln": "-----------------------------------------------------GFLTFKDVAPEFTLEEWESLSFAQRTLYMDVILENYNNLLSVENHVICE--KRGKVLDRDTECIVHEHVNIQEKFCKWEEISIVPLESTQSTPYKTNLRDPSLQSSNLKRHKAWKTREVYKYKDCMQFSNECAIVGVNSRIHIENKEHKNK----------------------EFDKDFVHEDKLALKQNIN-----------------------------GKNLHQCSECEKCFTKTRDLHLHQRIHT------------------------------------------------------------------------------------GKKRYKCNKCDKSFARESYLRHHQRIHTGEKPYKCSECDKCFTEKSSLRSHMRIHTGEKPYKCSECDKCFTEKGTLKRHMRIHTGEK--------------------------------------------------------PYKCSECDKCFRLQSHLNIHQRIHTGEKPYKCSECEKYFTDKCNFRIHQRIHTGEKPYKCSECDKCFTEKGTLRFHQRIHTGEKPYKCGECDKCFGHKSHLSNHQRIHTGEKPFKCSQCDKCFTQKGTV-------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2AWF2-1", "uniprot_id": "A2AWF2_MOUSE", "id": "A2AWF2-1", "name": "", "aln": "----------------------------MFAPHQESGRRTTKRMSASLENTAQCLLTFKDVFLDFSSEEWECLNFAQRTLYMDVMLENYNNLLFVENHCICGNYEKEKVLEQDTQHIVNEHGHNRKKSSKCNELRNVIHESSESTPYNTNHRDATLQSSNLKRHKTGTTKGVCTYKDCVNCLKGSSIISLNQGTHIEKKEHNRNKNLDEVLVSRQNNSEMNTYTCGEFDKCFTQSDNLQSQQRIYPGKKSYKYSESDKCFTQTSHLSIHHTIHSGEKPYKCSECDKCFTDKCTLRKHQRIHTGEKPYKCSECDKCFTDKCTLRKHQRIHTGEKPYKCNECDKCFTDKGSLRVHQRIHTGEKPYKCSECDKCFTQPSHLSIHRRIHSGEKPYKCSECDKCFTDKCTLRKHQRIHTGEKPYKCSECDKCFTEKFTLRKHQRIHTGEKPYKCNECDKCFTDKGSLRVHQRIHTGEKPYKCSECDKCFTKPSHLSIHRRIHSGEKPYKCSECDKCFTQPSPLSIHRRIHSGEKPYKCSECDKCFTDKGSLRVHQRIHIGEKPYKCSECDKCFTQPSHLSIHCRIHSGEKPYKCSECDKCFTHKGSLRVHHRIHAGEKPYKCSECDKCFTEKNGLRRHQRIHTGEKPYKCSECDKCFTRKSHLSIHQRIHTGEKLYKCSECDKCFTQQCHLSIHQKIHSGENLTNAMNATNALVTNTV", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :****** :*: ****.*.:***:*****:**.***** ***: * :: :**::**: **:* : ::: .* :*: : **::****:*: **.:*:*******:: . : : .****:: : .:*:.:*. ***:***:.. ***: *. ..: :: * *:: :: . *:***: . *: :****: *:* ***.:*** * :. ** *******:**:***:*** *::* * * *******:**.:*****. * :*: * ******* *****:*** * :. *. ***** *:*****.:*:* *:: : ** ***:*:************ **:** * *:*:*:*****.****.: .:. * * * ******:***:***** :. ", "identical_positions": 214, "similar_positions": 112, "identity": "30.01%" }, { "cls_id": "homologset.agr.MGI:1328323", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62876-1", "uniprot_id": "SNG1_RAT", "id": "Q62876-1", "name": "Synaptogyrin-1", "aln": "----------MEGGAYGAGKAGGAFDPYTLVRQPHTILRVVSWVFSIVVFGSIVNEGYLNNPEEEEEFCIYNRNPNACSYGVTVGVLAFLTCLVYLALDVYFPQISSVKDRKKAVLSDIGVSAFWAFFWFVGFCFLANQWQVSKPKDNPLNEGTDAARAAIAFSFFSIFTWAGQAVLAFQRYQIGA---DSALFSQDYMDPSQDSSMPYAPYVEPSAGSDPTGMGGTYQHPANAFDAEPQGYQSQGY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O55100-1", "uniprot_id": "SNG1_MOUSE", "id": "O55100-1", "name": "Synaptogyrin-1", "aln": "----------MEGGAYGAGKAGGAFDPYTLVRQPHTILRVVSWVFSIVVFGSIVNEGYLNNPEEEEEFCIYNRNPNACSYGVTVGVLAFLTCLLYLALDVYFPQISSVKDRKKAVLSDIGVSAFWAFFWFVGFCFLANQWQVSKPKDNPLNEGTDAARAAIAFSFFSIFTWAGQAVLAFQRYQIGA---DSALFSQDYMDPSQDSSMPYAPYVEPSAGSDPAGMGGTYQHPANAFDAEPQGYQSQGY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43759-1", "uniprot_id": "SNG1_HUMAN", "id": "O43759-1", "name": "Synaptogyrin-1", "aln": "----------MEGGAYGAGKAGGAFDPYTLVRQPHTILRVVSWLFSIVVFGSIVNEGYLNSASEGEEFCIYNRNPNACSYGVAVGVLAFLTCLLYLALDVYFPQISSVKDRKKAVLSDIGVSAFWAFLWFVGFCYLANQWQVSKPKDNPLNEGTDAARAAIAFSFFSIFTWAGQAVLAFQRYQIGA---DSALFSQDYMDPSQDSSMPYAPYVEP-TGPDPAGMGGTYQQPANTFDTEPQGYQSQGY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RH90-1", "uniprot_id": "A0A8M1RH90_DANRE", "id": "A0A8M1RH90-1", "name": "", "aln": "----------MQQ------QSIGSFELLTFIQQPHTGLRILCWLFSLVILGCIANEGQINRPDEVQKFCIFNRNQNACNYALGMASLAFICCLLFLAIDVHFPQISSIKHRKKVVLADVGTSAFWSFVWFVGFCFLANQWQVSKVEDDPLRSGGDAARAAITFCFFSIFSWAALTHVSLLRLR-------SVCFQEEYEQLCTQQHT-------------------HTHTPSHCV------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7JYV2-1", "uniprot_id": "SNG_DROME", "id": "Q7JYV2-1", "name": "Synaptogyrin", "aln": "MDMLNQILSINNGGAYGGGKAGGAFDPLTFAMKPQVVIRALCWLFSVVVFGCISSEGWTEK--DGKEYCLYNGDGMACKYGNMVGVFGFLASMGFMGGEFLFERMSSVKSRKRYVMADMGFSALWTFMYFVAFLYLWSQWSSSAPP--PLGIGAGSMKTAIWFCLFSIVSWALCALMAYKRFLIGAGDEFTSAFETDPANVVHQQAYGYSMDNDN--DQYSASPFGQPQQGGMEQQQSGMEYQQPTY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: *:*: *: :*:. :* :.*:**:*::*.* .** : : :::*::* : **.*. :. :.*: .: ::. :. * ::**:* **: *::*:* **:*:*.:**.* :* .**. * ** * .: ::** *.:***.:** : :: * : *. : : :. : . ", "identical_positions": 52, "similar_positions": 74, "identity": "21.05%" }, { "cls_id": "homologset.agr.MGI:1328324", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O54980-1", "uniprot_id": "SNG2_RAT", "id": "O54980-1", "name": "Synaptogyrin-2", "aln": "--------MESG--AYGAANAGGSFDLRRYVSQPQVVTRLVSMVLALIVFSCIFGEGYINLHSSDQLHCVFNRNEDACRYGSAIGVLAFLASAFFLVVDAFFSQISNATDRKYLVIGDLLFSALWTFLWFVGFCFLTNQWAATKPDDVLVGADSARAAITFSFFSIFSWGVLASLAYQRYKAGVDAFIQNYVDPTPDPTTAYAS------YPSAS---VENYQQPPFTQNVETT-EGYQP-----PPVY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O55101-1", "uniprot_id": "SNG2_MOUSE", "id": "O55101-1", "name": "Synaptogyrin-2", "aln": "--------MESG--AYGAANAGGSFDLRRFLSQPQVVTRLVSMVLALIVFSCIFGEGYTNIHTSDQLYCVFNQNEDACRYGSAIGVLAFLASAFFLVVDAFFSQISNATDRKYLVIGDLLFSALWTFLWFVGFCFLTNQWAATKPQDVRVGADSARAAITFSFFSIFSWGVLASLAYQRYKAGVDAFIQNYVDPTPDPNTAYAS------YPSAS---VENYQQPPFTQNVETT-EGYQP-----PPVY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43760-1", "uniprot_id": "SNG2_HUMAN", "id": "O43760-1", "name": "Synaptogyrin-2", "aln": "--------MESG--AYGAAKAGGSFDLRRFLTQPQVVARAVCLVFALIVFSCIYGEGYSNAHESKQMYCVFNRNEDACRYGSAIGVLAFLASAFFLVVDAYFPQISNATDRKYLVIGDLLFSALWTFLWFVGFCFLTNQWAVTNPKDVLVGADSVRAAITFSFFSIFSWGVLASLAYQRYKAGVDDFIQNYVDPTPDPNTAYAS------YPGAS---VDNYQQPPFTQNAETT-EGYQP-----PPVY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IUH5-1", "uniprot_id": "A0A0R4IUH5_DANRE", "id": "A0A0R4IUH5-1", "name": "Synaptogyrin", "aln": "--------MESRSVAYGASLAGAGFDLVKFIKQPQTVVRFLSWVFAIVVFSSITAEGYVNSTDEAEVRCVFNRNDGACHYGVGIGVIAFLACVGFLLADAILPLISNAQERKYIVMADLAFSGCWTFLWFVCFCLTADQWSKTS-DRSGIPTDAVHAVIAFSFFSIASWGALTYFAVVRFRQGVEEVTQSYTDPPPDLSSPYPSTYTPPTYPSFQNTGADIYQQPPFTPNPDPSGQTSFQ-----PPVY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7JYV2-1", "uniprot_id": "SNG_DROME", "id": "Q7JYV2-1", "name": "Synaptogyrin", "aln": "MDMLNQILSINNGGAYGGGKAGGAFDPLTFAMKPQVVIRALCWLFSVVVFGCISSEGWTEKDGKE--YCLYNGDGMACKYGNMVGVFGFLASMGFMGGEFLFERMSSVKSRKRYVMADMGFSALWTFMYFVAFLYLWSQWSSSAPPPLGIGAGSMKTAIWFCLFSIVSWALCALMAYKRFLIGAGDEFTSAFETDPANVVHQQA------YGYSMDNDNDQYSASPFGQPQQGGMEQQQSGMEYQQPTY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . ***.. **..** : :**.* * :. :::::**..* .**: : . *::* : **:** :**:.***. *: : : :*.. .** *:.*: **. ***::** * .**: : : :.: ::.* *.:*** **. : :* *: *. . :. * : * : *. .** : : *.*", "identical_positions": 60, "similar_positions": 69, "identity": "24.1%" }, { "cls_id": "homologset.agr.MGI:1328326", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JHC6-1", "uniprot_id": "CCN5_RAT", "id": "Q9JHC6-1", "name": "CCN family member 5", "aln": "---------MRGSPLIRLLATSFLCLLSMVCAQLCRTPCTCPWTPPQCPQGVPLVLDG----------CGCCKVCARR------------------LTESCEHLHVCE---PSQGLVCQPGAGPG---------GHGAVCLLDEDDGDCEVNG-----------------------------------------RRYLDGETFKPNCRVLC--------------------------------RCDDGGFTCLPLCSEDVTLP---------------SWDCPRPKRIQVPG-------------KCCPEWVCDQGVT-PAIQRSAAQGHQLSALVTPASADAPWPNWSTAWGPCSTTCGLGIATRVSNQNRFCQLEIQRRLCLP----------------------------------------------------------RPCLAARSHSSWNSAF-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z0G4-1", "uniprot_id": "CCN5_MOUSE", "id": "Q9Z0G4-1", "name": "CCN family member 5", "aln": "---------MRGNPLIHLLAISFLCILSMVYSQLCPAPCACPWTPPQCPPGVPLVLDG----------CGCCRVCARR------------------LGESCDHLHVCD---PSQGLVCQPGAGPS---------GRGAVCLFEEDDGSCEVNG-----------------------------------------RRYLDGETFKPNCRVLC--------------------------------RCDDGGFTCLPLCSEDVRLP---------------SWDCPRPRRIQVPG-------------RCCPEWVCDQAVMQPAIQPSSAQGHQLSALVTPASADGPCPNWSTAWGPCSTTCGLGIATRVSNQNRFCQLEIQRRLCLS----------------------------------------------------------RPCLASRSHGSWNSAF-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O76076-1", "uniprot_id": "CCN5_HUMAN", "id": "O76076-1", "name": "CCN family member 5", "aln": "---------MRGTPKTHLLAFSLLCLLSKVRTQLCPTPCTCPWPPPRCPLGVPLVLDG----------CGCCRVCARR------------------LGEPCDQLHVCD---ASQGLVCQPGAGPG---------GRGALCLLAEDDSSCEVNG-----------------------------------------RLYREGETFQPHCSIRC--------------------------------RCEDGGFTCVPLCSEDVRLP---------------SWDCPHPRRVEVLG-------------KCCPEWVCGQGGG-LGTQPLPAQGPQFSGLVSSLPPGVPCPEWSTAWGPCSTTCGLGMATRVSNQNRFCRLETQRRLCLS----------------------------------------------------------RPCPPSRGRSPQNSAF-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VVK3-1", "uniprot_id": "Q9VVK3_DROME", "id": "Q9VVK3-1", "name": "", "aln": "MLILLPLLGIFGNGFVAEVEANLSLGFKAIKLPRHPNPANCSVGNTTFAHGVTFKLDCKTQCVCENGRHACSTLCPNEQLPAPEDTISCRSPRLVEVPGHCCKMWLCENPTADVYATCHNSTTSGNWTACSRSCGLGTATRHTTTHAGCHQLSNLRLCENRRCDKDDHEDNKWSRSRPLTHKRKQHRAHSHSHQRYHHHKEHEEPAHRIRKGHECRSIQRLGPARIRLGECVSRKLYRPKLCGRCHRGVKCCAPAVSTTIQVELLCPLNAVDPINYVQRRQANKKRQMKEPQDDEDDDDDDDGDDNVEPEPVLQSAQLWDTVALEPIDQEFLQSHQIQIENKFIAVEWILKCECSTKNCNAGSSNISSNSNSNDNMANTNKYGYYNYKNNNRGRNHETNGEPNEPTNNNAGNNKDNEEDVVDSGNNLDHNDVDNMSSEQQPDIIPYPPSVGESSWKAEKLRQQHHWQQNT", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *. : .: :. : *. *. . . **.: ** .*. :*... : * :: :*: .. .*: .: .. * *: ...*. . * : . * :* : **. * * * * : : :. : :::: . ** * .. . : :.. :* .:..*. * :. **.* .: .: * .: .... :: ", "identical_positions": 34, "similar_positions": 82, "identity": "7.23%" }, { "cls_id": "homologset.agr.MGI:1328328", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0L9L9-1", "uniprot_id": "A0ABK0L9L9_RAT", "id": "A0ABK0L9L9-1", "name": "", "aln": "---MPGSATAIRQERLKTTHSRTIPLVLFTINEEDELQKNGNSRRPKASDG---YKIQGKRPAPSRPTSTLSGQ--------TSNHSGNKPDPPPVLRV--DDRQRLARERREEREKQLAARETVWLEREERARQHYERHLEARKKKLEDQRLKEERRRAAVEEKRRQRLEE--------------------------------------------------------DKERHEAVVRRTMERSQKPKQKYNRWSWGSPLHGSSSIHS---------------------------------------------------------------------------------------------------------------GDPDRRSVSTMNLSKHVDPVISKRLSSSSATLLNSPDRAR-----------------------------------------------------------------------------RLQLSPWESSVVSRLLTPTHSFLARSKSTAALSGDTAS--------CSPIT---------------------------------------------------------------------------TPFKTAHSRNPVDRPKL-----------------------------------FITPPEGSA---RRRTIHGISSYKRERE--HIPFHVSPGVRRTLSPSNLKARSPAPARLWPPSKSMPHLPGTPRPASSLTPGPVRAA---ASSSSPGNIRPVKREVKVEPEKKDPEK---KVTNDPTIKGRVPLVKVEEGTVEEGTPVKP----------------------------PDP--------AVPAPTPATDPAPAP-----------PSPSSVSVGVIPKTSAGTTDPEEATRLLAEKRRLAREQREKEERERKEKEELE------RQKIEELARRVAEERS-RREEEARRLEAEQARKREELALRLAEEERERWEREEVERAQKQKEEE-ARAREEAEKARQEREKHFQKEEQERLERKKRLEEIMRRTRRTETADKKTTGQSNGDMVK------GVLAGETEVSA-LPGVN-SPGHVESAGSTHGVALQQSKVTIESSPDLEKQPNENGMS------TQNENFEEIINLPVGSKASRLDVSN-----ENPEIPLKPILAFNDEGTLGPLPQVDGVQTQQTTEVI-----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88735-1", "uniprot_id": "MAP7_MOUSE", "id": "O88735-1", "name": "Ensconsin", "aln": "-------------------------MAEQGAGGDGHRGGDGATHSDPASDG---YKVQEKRTAPSRPTSTVSGQ--------TSNHSGNKPDPPPVLRV--DDRQRLARERREEREKQLAARETVWLEREERARQHYERHLEARKKKLEDQRLKEERRRAAVEEKRRQRLEE--------------------------------------------------------DKERHEAVVRRTMERSQKPRQKSNRWSWGSPLHGSSSIHS---------------------------------------------------------------------------------------------------------------GDPDRRSVSTMNLSKHVDPVISKRLSSSSATLLNSPDRAR-----------------------------------------------------------------------------RLQLSPWESSVVSRLLTPTHSFLARSKSTAALSGDTAS--------CSPII---------------------------------------------------------------------------MPFKAAHSRNPVDRPKL-----------------------------------FVTPPEGSA---RRRTIHGLASHKREREREHVPFHVSPGARRTLSPSNLKARSPAPARLWLPSKSMPHLPGTPRPASSLPPGSVRAASAQAPSSSPGNIRPFKREVKVEPEKKDP---------LPAVKSRVPLVKVEEVTVEEGTPVKP----------------------------PEPAAPASAPIATPAPAPATDPAPVP-----------APSSTVTVGVVPKTSAGTTDPEEATRLLAEKRRLAREQREKEERERKEKEELE------RQKIEELARRVAEERS-RREEEARRLEEEQAREKEELALRLAEEERERWEREEVERVQKQKEEE-ARAREEAERARQEREKHFQKEEQERLERKKRLEEIMRRTRRTETADKKTTEQRNGDIAK------GVLTGEPEVPA-LPCMA-SSGNGESAESPHGVALQQSEVTTESSPDLEKQPNENGMS------IQNENFEEVINLPVGSKASRLDVTN-----ENPEIPLKPILAFNDEGTLGPLPQVDGVQTQQTAEVI-----------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14244-1", "uniprot_id": "MAP7_HUMAN", "id": "Q14244-1", "name": "Ensconsin", "aln": "-------------------------MAELGAGGDGHRGGDGAVRSETAPDS---YKVQDKKNASSRPASAISGQ--------NNNHSGNKPDPPPVLRV--DDRQRLARERREEREKQLAAREIVWLEREERARQHYEKHLEERKKRLEEQRQKEERRRAAVEEKRRQRLEE--------------------------------------------------------DKERHEAVVRRTMERSQKPKQKHNRWSWGGSLHGSPSIHS---------------------------------------------------------------------------------------------------------------ADPDRRSVSTMNLSKYVDPVISKRLSSSSATLLNSPDRAR-----------------------------------------------------------------------------RLQLSPWESSVVNRLLTPTHSFLARSKSTAALSGEAAS--------CSPII---------------------------------------------------------------------------MPYKAAHSRNSMDRPKL-----------------------------------FVTPPEGSS---RRRIIHGTASYKKERERENVLFLTS-GTRRAVSPSNPKARQPARSRLWLPSKSLPHLPGTPRPTSSLPPGSVKAAPAQVRPPSPGNIRPVKREVKVEPEKKDPEKEPQKVANEPSLKGRAPLVKVEEATVEERTPAEPE-------------------------VGPAAPAMAPAPASAPAPASAPAPAPVPTPAMVS-----APSSTVNASASVKTSAGTTDPEEATRLLAEKRRLAREQREKEERERREQEELE------RQKREELAQRVAEERTTRREEESRRLEAEQAREKEEQLQRQA-EERALREREEAERAQRQKEEE-ARVREEAERVRQEREKHFQREEQERLERKKRLEEIMKRTRRTEATDKKTSDQRNGDIAK------GALTGGTEVSA-LPCTTNAPGNGKPVGSPHVVTSHQSKVTVESTPDLEKQPNENGVS------VQNENFEEIINLPIGSKPSRLDVTNS----ESPEIPLNPILAFDDEGTLGPLPQVDGVQTQQTAEVI-----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TG86-1", "uniprot_id": "A0AB32TG86_DANRE", "id": "A0AB32TG86-1", "name": "", "aln": "-------MPAPLRTRRGACRSAVPSLSTIAEEEEGQRSRKRRRRGGGGSDY---LLRADEKSSWSRPDSSASGQYTYTIPSPTEIHTVTKPEP-LMLKN--DERQRLARERREELDKQNAVRGSKWQEREERARQFHERQLEERKKRLEEQRMKEDKRRAAVEEKRRQKLEE--------------------------------------------------------EKVRYEAVIRRTMERSQRARPKSNRWSWGGTLSVSTSHNSGFDDCALFPLD-------------------------------------------------------------------------------LAGLEHYHGVFSLAHQQQMRSKYADRRSVSTMNLSKHTDPVISKRLSSSSATLLNSPDRALRKQTSFSSSCLLKKTLSKSQISREKTPQ------------------------------------------DKTAGMRRMPLTPWENTVISRLQTPTHSYLARSRSAMSLSGEAVTPVCPRSASCHPMSS--------------------------------------------------------------------------MSFKSIQSR-SAERPMK-----------------------------------AGLNLERPI---RAGFIPPDGSNRRKIT-QNIMIDRKDKDNVRKSWSNLSYPTPSLS-LFTP-KRAPSPVGHRSRVTNPSPNRSSTAKPFQKTPNPKKSRSPPPPASIPLSHSNPSLS------PGNLRPSRPTSESLRVTAEREAAKKE--------------------------------------DVEPPKTEPEAPLTTTE----------PSSEASGSSPGGRPSAGTTDPEEASRLLAEKRRQAREQREREEEEKRQQEEAE------RRSREEMARRKAEERA-KREEEAQR-QAEEKRRKEEEEMRLE-EERAQREREEAERLQKQKEEEEARQKEEAERLRLEREKHFQKEEAERMERKKRLEEIMKRTRR---SDQKTTPQRNGDVSQQSGQDPGSVSGGPSVSVSDPLASETLETVQSDSNGHTGPSYITPVLPTSGHSMSALLRENGT--------INETFEQVIEVPLANKLSRQDGDGEELDREEEEERKRPFLAFRENGSTHNVSELNEEPTL-----------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M3AIT0-1", "uniprot_id": "A0A8M3AIT0_DANRE", "id": "A0A8M3AIT0-1", "name": "", "aln": "---MPAHLSLAEQEREWRKTGRTVEMGFKAISEKGQLKTCDTAKKQRDSRSEVKTTVLEHKRKACTPLHSKPPQ------MKINSQNGNNAES-NVLKV--DERLRMARERREAYQKQIALRERGWLAREERAKQIYEKHLEERRKKLEEQRQREERRRTAVEEKRRQRLKE--------------------------------------------------------DRERYESVVRKTIEKSLKAKQKPG----------------------------------------------------------------------------------------------------------------------------------------------HCSRKVTK----------NDNKNAK-----------------------------------------------------------------------------RRSLSQWEIDLVRRLQTPTVSYLARSRSAVCLSRDTVVHVCRRSVSCHTMN----------------------------------------------------------------------------SSTNLHCGKVPNRPGG-----------------------------------SNVTIRRTT---NRELVAKDNTEGQDLK--------KLQLQRSTTTTEIKP------------KQDTEPPENTVLATSWLQNRSHVRNATLKQDS---LPPLPEEEDLEPE--------------PEPSSSHTKSEKTRCLKENSLQLNT---------------------------------------ASNGPLHPLQVSQIP-----------NGPSQIADSAQVRPTSWTKDPEEASRILAEKRRQARLQKEKEEEERRQKEETE------RKRREELARRRAEERA-RQEAEALKLEEEKRKREQEEQLKAA-AENARIQKEEENRLQQQREEE-ARQSVLAEQQRVEREIRFQKEKAERQERKKRLEQIMKRTRKTDSVDKKAASVKDN-------------------------------------------------------------------------LPCENVNPVIRLAGPGKTPKLELRD--------EEDMLPTVAFKERRSFRSLSGLDEIQTHQQTEVI-----------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A8JNK1-1", "uniprot_id": "A8JNK1_DROME", "id": "A8JNK1-1", "name": "", "aln": "MASLGGQHGNISTNPEVENTAKRPESREGSAERKAHAFAPAKISGCSAGATLHWFAQVGGQISASEDDSQASKDREEKLKYARDRQNEERHRKIEELRAQAEAAQRYREQKEEERRRRIEEIRTRDTEKRHQVEERKKAIFEAEKERREYILKKNQERESRIEVKKRDRNSIGFAFGSSTPRLLDVPADYGLVSPSAFWGQRRSTSISNVAGASLTRRSSERELADSGAKKRASSSTDRQDDHRRKSSSMYEVFNWGYSNDEPPKRFSLSIAGSEINIDGPANPHPPPTSKQTANAHRPTNLTTTTATSTTTAGHNNFNNNNSYRKEDSVDSSPMVFRSVYRRKTDLMPTIPSPRDGHYGSRGSLSSTPARTPGRAYSMNRLDQLAQPIRRNGEHMRAILERERRERELEMLDETASLGGGGGRRGAGSSARARRAGSAGSGSSSAAGIMSRSMTHLAGGGGQRERGKYSLGGGISTSFRPLASGAGGQRDSTSKSMTQISSWSVYGSTAPQQPPPNHLHHLRQSTLGLQTAATKKYLQSSFASASSFNSASFRANATGRGRQQQYAISTNPHRFLDLDPNSLLLMNSASLLVNAGSRSGNATPGGHFNNSRPGSAMSTSTNMSTSGLVPRRPATAPRKPRPASIAGTGMSLEEINKLKRDQKPPVKTTAASPSAQTTPKRTANLMSTSLIVTSSSSRLSSAEKKTPSKREPPVPKAASASKALPSRTASSERISRLTKEPKTKDTSAMTRSMIVTSSSTSTITKPAPAPVAPTSAPVPEQNGVAKEVEKTTADEPVPEAEVPTEAPVVVPSVSKAEKEALNTEKTEEGARQEEEQILAVESVPEALVTSINVEEKSDEGNEKEVPKPQEQAAPKKPSRSKENSEVRELTPPEGADLMTASMMAKKITTEEEAKAALAERRRLAREEAERQAELERQRLEAERLAEIKAQEEEAERQRLFEEESTRLAEEQRRGEEERLRKAIEEAQQREEEEKRRREEEEKQRVEREEAEK--KAKEEAEKQRVEVAERLKREEKEREERRKRVEAIMLRTRKGGAATTPSKDANDKAAPAATAPENNSSSNSSVTGSSNNSAEGSPSAADSTPAPTATETVQEAPNSQAMYEQSVLDKENSLINSFSTMIIDENAKNLQQVSNGKLLVDFESTNTVPAVANGNGHIENVNNKNDINLLQDVVAPVATQLIDLSIESQDLHLNNNNSLLTSTAATTTLVTADSHENKDISLL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : . . : . :. . *: : * .::.* :: :..:..: : :* .::: * :::.*.: :* *:*:: . : * .: : :: :. : : : :. :: *. *. ..* : :.: :. . . . . * . . : : . . : :: . . . . . . . . *. . .. : . ***. ***:** ** : *:: . .::: * * : * :* **.: : * : : *. :. * : *. :.** :* :::. *: : **: * * ::::*: ** **:**:* ** ***: : : *. : : .:. : . : : : ", "identical_positions": 58, "similar_positions": 147, "identity": "4.67%" }, { "cls_id": "homologset.agr.MGI:1328337", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q80Z32-1", "uniprot_id": "ORC1_RAT", "id": "Q80Z32-1", "name": "Origin recognition complex subunit 1", "aln": "MPSYVTRQKTRQTFSWV--GRPLP-NRKQFYQMYKEICMKINGCS-EIHIKVGQFVLIQGEDNQKP------YVAKLIELFEN-GSEVPPKKYARVQWFVRFCEIPIPKRHLLGRRPSAQEIFWYDCSDCDNDIHVETIIGPVQVVALAPEDEIPVNQKSEETLFVKLSWN-----------KKNFAPLPPEELAALRR-----LECQKP-------------LEAKTKSVKSPSWSTAEQEVKRIESSHSTSRSYQDPAHTVT--------PNAMKSLECG--GFTRKPNMRLSRK-ILCDSLDSQKTCKRRAAFSETTSPPKKP-QPGEIKTSS--------ALETLGKNGHTQPFFAKSS--------MVLRTRGTAVK--TTKLTVESALSPVRSRSR-------YSVAPSVGLTPQYIG-RKAKEQETHKEPIHTSLRARRR------SSLLTLKRIKQQLWLLD--------DDKSDQEEEESISSVEVSDSSSEEE-DESVPSPP--TGKPVGQSRTRRTASK--PSSQTPSKSPKKTFR---PRPPLHATPQIRDRNLAVQEPASVLEEARLRLHVSAVPDSLPCREQEFQDIYSFVESKLLDGTGGCMYISGVPGTGKTATVHEVIRCLQQAAQTNDVPPFEYVEVNGMKLTEPHQVYVQILQKLTGQKATANHAAELLAKQFC-SRGSQKETTVLLVDELDLLWTHKQDVLYNLFDWPTHKGARLVVLTIANTMDLPERIMMNRVASRLGLTRMSFQPYSHSQLKQILVSRLKHL--------------------------------------KAFEDDAVQLVARKVAALSGDARRCLDICRRATEICEVS-------------------------------------------HQRGDSQCLVTVAHLMEAIDEMFSSSYITAIKNSSVLEQSFLRAIIAEFRRSGLEEATFQQIYSQHVALCRMEGLPYPTMSETMAVCSR--------------------LGSCRILLVEPSRNDLLLRVRLNVSQNDVLYALKEE------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z1N2-1", "uniprot_id": "ORC1_MOUSE", "id": "Q9Z1N2-1", "name": "Origin recognition complex subunit 1", "aln": "MPSYLTRQKTRQTFSWV--GRPLP-NRKQFQQMYREICMKINDGS-EIHIKVGQFVLIQGEDNKKP------YVAKLIELFQN-GAEVPPKKCARVQWFVRFLEIPVSKRHLLGRSPPAQEIFWYDCSDWDNKINVETIIGPVQVVALAPEEVIPVDQKSEETLFVKLSWN-----------KKDFAPLPPEVLAALREQ-EDSPEWQKP-------------LKAKIKNVKSPARNTTEQEVKGIKSNHSTSKFHQTPANIVI--------PNAKKSLELDGLGFTRKPNTRWSKK-SSCDSLDYQKTSKRRAAFSETTSPPKKPNKPREIKPSS--------ALETRVKNGQTQPFCAKSS--------VVLRARNPAMT--TTKLGVDNTLSPIRNGLR-------SSVVPSGGLTPVYIR-RKAKEQETHKEPIRTS-RVHRK------SSLLTLKRIRQQLCLLD--------GDDRDQEEEESV------DSESEEE-DEFISSLP--TRNSLGQSRTR----------QTPSKSPQKNPK---PRTPHRATPQIRDRNLAVQEPASALEEARLRLHVSAVPDSLPCREQEFQDIYSFVESKLLDGTGGCMYISGVPGTGKTATVHEVIRCLQQAAETDDVPPFQYVEVNGMKLTEPHQVYVQILKKLTGQKATANHAAELLAKQFC-GQGSQKETTVLLVDELDLLWTHKQDVMYNLFDWPTHKGAHLIVLTIANTMDLPERIMMNRVSSRLGLTRMSFQPYSHSQLKQILVSRLRNL--------------------------------------RAFEDDAIQLVARKVAALSGDARRCLDICRRATEICELS-------------------------------------------HLRGDSLSLVTVAHLMEAIDEMFSSSYITAIKNSSVVEQSFLRAIIAEFRRSGLEEATFQQIYSQHVALCRMEGLPYPTMSETMAVCSR--------------------LGSCRLLLVEPSRNDLLLRVRLNVSQNDVLFALKEE------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13415-1", "uniprot_id": "ORC1_HUMAN", "id": "Q13415-1", "name": "Origin recognition complex subunit 1", "aln": "MAHYPTRLKTRKTYSWV--GRPLL-DRKLHYQTYREMCVKTEGCSTEIHIQIGQFVLIEGDDDENP------YVAKLLELFED-DSDPPPKKRARVQWFVRFCEVPACKRHLLGRKPGAQEIFWYDYPACDSNINAETIIGLVRVIPLAPKDVVPTNLKNEKTLFVKLSWN-----------EKKFRPLSSELFAELNKPQESAAKCQKP-------------VRAKSKSAESPSWTPAEHVAKRIESRHSASKSRQTPTHPLT--------PRARKRLELG-----NLGNPQMSQQ-TSCASLDSPGRIKRKVAFSEITSPSKRS-QPDKLQTLSP-------ALKAPEKTRETGLSYTEDDKKASPEHRIILRTRIAASK--TIDIREERTLTPISGGQR-------SSVVPSVILKPENIKKRDAKEAKAQNEATSTPHRIRRK------SSVLTMNRIRQQLRFLG--------NSKSDQEEKEILPAAEISDSSSDEE-EASTPPLP--RRAPRTVSRNLRSSLK--SSLHTLTKVPKKSLK---PRTPRCAAPQIRSRSLAAQEPASVLEEARLRLHVSAVPESLPCREQEFQDIYNFVESKLLDHTGGCMYISGVPGTGKTATVHEVIRCLQQAAQANDVPPFQYIEVNGMKLTEPHQVYVQILQKLTGQKATANHAAELLAKQFC-TRGSPQETTVLLVDELDLLWTHKQDIMYNLFDWPTHKEARLVVLAIANTMDLPERIMMNRVSSRLGLTRMCFQPYTYSQLQQILRSRLKHL--------------------------------------KAFEDDAIQLVARKVAALSGDARRCLDICRRATEICEFS-------------------------------------------QQKPDSPGLVTIAHSMEAVDEMFSSSYITAIKNSSVLEQSFLRAILAEFRRSGLEEATFQQIYSQHVALCRMEGLPYPTMSETMAVCSH--------------------LGSCRLLLVEPSRNDLLLRVRLNVSQDDVLYALKDE------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QLF9-1", "uniprot_id": "F1QLF9_DANRE", "id": "F1QLF9-1", "name": "Origin recognition complex subunit 1", "aln": "MSRYITRLSMRRTYKWN--GRPVGEDRKLRRQYYGSMSISVDGRTEDVTVSLGQYILIEGENDDNP------FVAQLLKLYTD-ESG--KMKTAVVQWFVRMYEVPQYKRKLLGRDPHPQEVFFYQDSSCDNEVDGESILAPVQIMYIAPEHPFPEG-KSKDMLFVKHSWD-----------TKSFQAVDPELIEPPPSPKSPPPSSRGPQARPLPTPDPSIMKRAITGAITRGSMSTGKMSSTEAESLHSASKLSAAKALSAKRRSRASSGPHVRKKLELCS------PSKNMSRDDVLGEILDKHIDTDKTLMSKMNTSPSGRISISIRLTPLKCNEEQQILPLSSHSPDKPTLTAYGSDSATSVFLGVPALGDDDPESLNNTGRTPRKREATPRRASVRGLKARTPSRRKDSASLKEPALTALAEEEHEDSPAQTAATPRSKRK------SAQLVSSRIRKQLNLIANKFDLQSDGEDGDEDDCFVPSKIDLQSSSDEEL-EAKVDSEDELVVKKRRGSRTPRATDKSCVSARTPCKTPSKKAAPSTPRTPRHATPSIPSRTAPARKPGNVLEEARARLHVSAVPESLPCREQEFQDIYNFVESKVIDGTGGCMYISGVPGTGKTATVHEVIRSLQQSAEQDEIPHFNFIEINGMKMTDPHQAYVQILQKLTDQKATSDHAAALLEKRFS-APAPKKETTVLLVDELDLLWTRKQNVMYNLFDWPTRRNARLVVLTIANTMDLPERIMINRVASRLGLTRMSFQPYTFKQLQQIITSRLNRV--------------------------------------KAFEEDALQLVSRKVAALSGDARRCLDICRRATEICEHS-------------------------------------------GNQQKGSGLVGMSHVMEALDEMFSSSYIAAIRSASVQEQLLLRAVIAEFRRLGLEEATFQQVFVQHQALCRVEGLQPVSVSEGLLVCQR--------------------LGSCRLLLLEGSRLDLFLRIRLNVSQDDVLYALKAD------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O16810-1", "uniprot_id": "ORC1_DROME", "id": "O16810-1", "name": "Origin recognition complex subunit 1", "aln": "MVNKENARSVGQQVKWI--GSQDE-LPPVKNLEHKNVYFYQKCIYGPLTLSVGDFILVSNADAAEPDTVSGCDVARILHMYELRELTDREPCRAIVQWYSWPKAIPHNKYDDDEVAIDFSLEVIEEHRPYDNDVALGAIYRKCIVLEGTSKTSAEEILKRHANKLKSTACPMFVSRYRFVKVKRSYRLIPLEIHLEQPEDNARPTRSSRK---------SLTAHRESKRSISARHDDTAGNKGSSVEKRRRASMAASSSVEFIDVN--SFICENKVSPIKIVGGRSVVRLSEKKNAPEINANYLPASPLTEKNAKVETPKSRASAARRNLNLSLDRGADTTADSDCLNYSIVQQTPDPKTPSNDMKIKLRLSERRRSVRLASMDVDPLSLEEAVQEPNAQGR--------KRLGVANGDIYHTPTKKSKEPLESAAATEQTPSTRRKSILKSATSRLAEGTPRRSIHLSNIVEQRVFEDDEIISTPKRGRSKKTVQDNDEDYSPKKSVQKTPTRTRRSSTTTKTATTPSKGITTATATPMTPSQKMK-KIRAGELSPSMQQRTDLPAKDSSKSELQLAREQLHVSVVPKSLPCREREFENIYAFLEGKIQDQCGGCMYVSGVPGTGKTATVTGVIRTLQRMAKQNELPAFEYLEINGMRLTEPRQAYVQIYKQLTGKTVSWEQAHALLEKRFT-TPAPRRVTTVLLVDELDILCNRRQDVVYNLLDWPTKSAAKLVVVTIANTMDLPERLLMGKVTSRLGLTRLTFQPYSHKQLQEIVTARLGGS--------------------------------------ETFKGEAVQLVARKVAAVSGDARRALDICRRATEIADTA-------------------------------------------AVK-----CVTMLHVQQALAEMIASAKVQAIRNCSRMEQIFLQAIAAEVTRTGVEETTFMGVYQQVETIAAFMGVTFPPPGRALRLCSK--------------------LGAERLIISEHSRNDLFQKILLNVSADDIHYALRVEEMVN--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P54784-1", "uniprot_id": "ORC1_YEAST", "id": "P54784-1", "name": "Origin recognition complex subunit 1", "aln": "MAKTLKDLQGWEIITTDEQGNIIDGGQKRLRRRGAKTEHYLKRSSDGIKLGRGDSVVMHN------------EAAGTYSVYMIQELRLNTLNNVVELWALTYLRWFEVNPLAHYRQFNPDANILNRPLNYYNKLFSETANKNELYLTAELAELQLFNFIRVANVMDGSKWE------------------------------------------------------VLKGNVDPERDFTVRYICEPTGEKFVDINIEDVKAYIKK-------------------------VEPREAQEYLKDLTLPSKKKEIKRGPQKKDKATQTAQISDAETRATDITD-------NEDGNEDESSDYESPSD--------IDVSEDMDSGEISADELEEEEDEEEDEDEEE----------KEARHTNSPRKRGRKIKLGKDDIDASVQPPPKKRG------RKPKDPSKPRQMLLISS----------------CRANNTPVIRKFTKKNVARAKKKYTP-FSKRFKSIAAIPDLTSLPEFYGNSSELMASRFEN---KLKTTQKHQIVETIFSKVKKQLNSSYVKEEILKSANFQDYLPARENEFASIYLSAYSAIESDSATTIYVAGTPGVGKTLTVREVVKELLSSSAQREIPDFLYVEINGLKMVKPTDCYETLWNKVSGERLTWAASMESLEFYFKRVPKNKKKTIVVLLDELDAMVTKSQDIMYNFFNWTTYENAKLIVIAVANTMDLPERQLGNKITSRIGFTRIMFTGYTHEELKNIIDLRLKGLNDSFFYVDTKTGNAILIDAAGNDTTVKQTLPEDVRKVRLRMSADAIEIASRKVASVSGDARRALKVCKRAAEIAEKHYMAKHGYGYDGKTVIEDENEEQIYDDEDKDLIESNKAKDDNDDDDDNDGVQTVHITHVMKALNETLNSHVITFMTRLSFTAKLFIYALLNLMKKNGSQEQELGDIVDEIKLLIEVNGSNKFVMEIAKTLFQQGSDNISEQLRIISWDFVLNQLLDAGILFKQTMKNDRICCVKLNISVEEAKRAMNEDETLRNL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . . . . * . . : : *: ::: . .* :: . * : . . ..: : : : . . . . . * : . .: . : .. . . . : . :* :: : : . .. : : ..: . . . *: : . . **.**.** .** . : . . :*::*.**.*** ** *:: * : ::* * ::*:**:::..* : * : ::::.: : : * * : * *:*:**** : .: *:::**:::*.* *:*:*:::********* : .:::**:*:**: * *:..:*::*: ** :. :*:::.:****::******.*.:*:**:**.: * : * :*: * : * : : * : :: *: . : * :* : : : : . * : .: * ::: : : * : : **:* :: *:. : ", "identical_positions": 104, "similar_positions": 183, "identity": "9.85%" }, { "cls_id": "homologset.agr.MGI:1328350", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JYF9-1", "uniprot_id": "A0A0G2JYF9_RAT", "id": "A0A0G2JYF9-1", "name": "Matrilin-3", "aln": "MLFSALLRNLPGLLLLLWPLLLLPPPAAPGRLTRASVRRLGTRVPGGSPGHFSARATSTRAPYSGV------RGSGVCKSRPLDLVFIIDSSRSVRPLEFTKVKTFVSRIIDTLDIGATDTRVAVVNYASTVKIEFQLNTYSNKQALKQAVARITPLSTGTMSGLAIQTAMEEAFTVEAGARGPTSNIPKVAIIVTDGRPQDQVNEVAARARASGIELYAVGVDRADMESLKMMASKPLEDHVFYVETYGVIEKLSARFQETFCALDQCMLGTHQCQHVCVSDGDGRHHCECSQGYTLNADGKTCSAIDKCALNTHGCEQICVNDRNGSYHCECYEGYTLNADRKTCAAQDKCALGTHGCQHICVNDGAGSHHCECFEGYTLNADKKTCSVRDKCALGTHGCQHICVSDGAVSYHCDCFPGYTLNDDKKTCSDIEEVRSLISIEDACSCGATLAFQEKVSSHLQKLNTKLDNILKKLQVTEYGQLHR-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35701-1", "uniprot_id": "MATN3_MOUSE", "id": "O35701-1", "name": "Matrilin-3", "aln": "MLLSAPLRHLPGLLLLLWPLLLLPSLAAPGRLARASVRRLGTRVPGGSPGHLSALATSTRAPYSGG------RGAGVCKSRPLDLVFIIDSSRSVRPLEFTKVKTFVSRIIDTLDIGATDTRVAVVNYASTVKIEFQLNTYSDKQALKQAVARITPLSTGTMSGLAIQTAMEEAFTVEAGARGPMSNIPKVAIIVTDGRPQDQVNEVAARARASGIELYAVGVDRADMESLKMMASKPLEEHVFYVETYGVIEKLSARFQETFCALDQCMLGTHQCQHVCVSDGDGKHHCECSQGYTLNADGKTCSAIDKCALSTHGCEQICVNDRNGSYHCECYGGYALNADRRTCAALDKCASGTHGCQHICVNDGAGSHHCECFEGYTLNADKKTCSVRNKCALGTHGCQHICVSDGAVAYHCDCFPGYTLNDDKKTCSDIEEARSLISIEDACGCGATLAFQEKVSSHLQKLNTKLDNILKKLKVTEYGQVHR-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15232-1", "uniprot_id": "MATN3_HUMAN", "id": "O15232-1", "name": "Matrilin-3", "aln": "MPRPAPARRLPGLLLLLWPLLLLPS-AAPDPVARPGFRRLETRGPGGSPGRRPSPAAPDGAPASGTSEPGRARGAGVCKSRPLDLVFIIDSSRSVRPLEFTKVKTFVSRIIDTLDIGPADTRVAVVNYASTVKIEFQLQAYTDKQSLKQAVGRITPLSTGTMSGLAIQTAMDEAFTVEAGAREPSSNIPKVAIIVTDGRPQDQVNEVAARAQASGIELYAVGVDRADMASLKMMASEPLEEHVFYVETYGVIEKLSSRFQETFCALDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHGCEHICVNDRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVNDRTGSHHCECYEGYTLNADKKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPGYTLNEDKKTCSATEEARRLVSTEDACGCEATLAFQDKVSSYLQRLNTKLDDILEKLKINEYGQIHR-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q68EK6-1", "uniprot_id": "Q68EK6_DANRE", "id": "Q68EK6-1", "name": "", "aln": "------MKSFIGSLVYCLSVLLLDLCDSYD-LNNPSYILAQSYAQRRNNG----LPHRTLNPAATD---------SQCRSRPLDLVFIIDSSRSVRPGEFEKVKIFLADMVDTLDVGPDATRVAVVNYASTVKIEFLLKSHLTKDTIKQAITRIEPLAAGTMTGMAIKKAMDEAFTEKSGARPKSKNISKVAIIVTDGRPQDQVEEVSAAARASGIEIYAVGVDRADMRSLKLMASNPLEDHVFYVETYGVIEKLTSKFRETLCGMDACAMG-HDCEHICVSSGS-------------------------------------------SYYCQCRKGYILNEDQKTCALKQ--------------------------------------------------------------------------------------VKVEIVQDPCMCEARLAFQRQTQTSIQDLNAKLAAVTRKIEQMEN-MLGRM", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : * *: .:*** : . : ... : . * . * : . *:****************** ** *** *:: ::****:*. **************** *::: *:::***: ** **::***:*:**:.**:**** ::*** .**.***************:**:* *:*****:********** ***:***:***:**************:::*:**:*.:* * :* *:*:*:*:*.*. **:*:* ** ** *::**: : : :*.* * * **** :..: :* **:** : .*:: * : * ", "identical_positions": 176, "similar_positions": 82, "identity": "36.07%" }, { "cls_id": "homologset.agr.MGI:1328351", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P20068-1", "uniprot_id": "NEUT_RAT", "id": "P20068-1", "name": "Neurotensin/neuromedin N", "aln": "-------MIGMNLQLVCLTLLAFSSWSLCSDSEEDVRALEADLLTNMHASKVSKG--SPPSWKMTLLNVCSLINNLNS--AAEEAGEMRDDDLVAKRKLPLVLDDFSLEALLTVFQLQKICRSRAFQHWEIIQEDILDHGNEKTEKEEVIKRKIPYILKRQLYENKPRRPYILKRASYYY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D3P9-1", "uniprot_id": "NEUT_MOUSE", "id": "Q9D3P9-1", "name": "Neurotensin/neuromedin N", "aln": "-------MRGMNLQLVCLTLLAFSSWSLCSDSEEDVRALEADLLTNMHTSKISKA--SPPSWKMTLLNVCSLINNVNS--PAEEAGDMHDDDLVGKRKLPLVLDGFSLEAMLTIFQLQKICRSRAFQHWEIIQEDILDNVNDKNEKEEVIKRKIPYILKRQLYENKPRRPYILKRGSYYY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P30990-1", "uniprot_id": "NEUT_HUMAN", "id": "P30990-1", "name": "Neurotensin/neuromedin N", "aln": "------MMAGMKIQLVCMLLLAFSSWSLCSDSEEEMKALEADFLTNMHTSKISKA--HVPSWKMTLLNVCSLVNNLNS--PAEETGEVHEEELVARRKLPTALDGFSLEAMLTIYQLHKICHSRAFQHWELIQEDILDTGNDKNGKEEVIKRKIPYILKRQLYENKPRRPYILKRDSYYY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0A7H8E2-1", "uniprot_id": "A0A0A7H8E2_DANRE", "id": "A0A0A7H8E2-1", "name": "Neurotensin/neuromedin N", "aln": "MCRNCGTTNNMQMQLTSFLLLFLLCNGLCSDIDQGKRAIEDEVLRSLLTSKVKASRHIAPLWQLPLQDVCRMVNGLGDSWLEAWANEEAAEDTEVHADYEQRVSGTLLQMLEEMHDIQNLCR--VLQPRELQDEQEYLELEQNSDSP--LKRKSPYILKRQLRTNKSRRPYILKRSVIY-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .*::**..: ** : . .**** :: :*:* :.* .: :**:. . * *::.* :** ::*.:.. :.: :: : . :.. *: : :.:::::*: .:* *: :*: :::. . :*** ******** **.******** * ", "identical_positions": 47, "similar_positions": 63, "identity": "26.11%" }, { "cls_id": "homologset.agr.MGI:1328352", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88890-1", "uniprot_id": "SH21A_MOUSE", "id": "O88890-1", "name": "SH2 domain-containing protein 1A", "aln": "MDAVTVYHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYQGYIYTYRVSQTETGSWSAETAPGVHKRFFRKVKNLISAFQKPDQGIVTPLQYPVEK-SSGRGPQAPTGRR-DSDICLNAP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B2RZ59-1", "uniprot_id": "SH21A_RAT", "id": "B2RZ59-1", "name": "SH2 domain-containing protein 1A", "aln": "MDAVTVYHGKISREMGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYQGYIYTYRVSQTETGSWSAETAPGVHKRFFRKVKNLISAFQKPDQGIVTPLQYPVEK-SSARSPQAPTGRR-DSDICLKAP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O60880-1", "uniprot_id": "SH21A_HUMAN", "id": "O60880-1", "name": "SH2 domain-containing protein 1A", "aln": "MDAVAVYHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTETGSWSAETAPGVHKRYFRKIKNLISAFQKPDQGIVIPLQYPVEKKSSARSTQGTTGIREDPDVCLKAP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F0N7-1", "uniprot_id": "E7F0N7_DANRE", "id": "E7F0N7-1", "name": "", "aln": "MESLSVYHGAISREMCEMRLNEAGKDGSYLIRDSESVAGAYCLCVLCKGFVYTYRLQKDSAGSWAAETAPGQTKRLFRKVKNLISAFEKPGQGIAIPLLYPVTIQKSY--------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A2BGK3-1", "uniprot_id": "A2BGK3_DANRE", "id": "A2BGK3-1", "name": "", "aln": "MEDLAEYHGSISKKQAEDILCSTGRDGSYLIRDSLSSAGAYCVCVLCDGWVYTYRIFN-KGGLWTIEMAPGMKERLFRNVSNLIAAFKMPDQGITFPLLYPVNKPKH---------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: :: *** **:: * * :* *****:*** * .*.**:*** .*::****: : . * *: * *** :* **::.***:**: *.***. ** *** . ", "identical_positions": 52, "similar_positions": 26, "identity": "40.62%" }, { "cls_id": "homologset.agr.MGI:1328354", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88954-1", "uniprot_id": "MPP3_RAT", "id": "O88954-1", "name": "MAGUK p55 subfamily member 3", "aln": "----MPVLSEDSGLHETLALLTSQLRPDSNHR--EEMGFLRDVFSEKSLGYLMKIHEKLRYYERQS-PTPVLHSAMALAEDVMEEL-QAASVHSDERELLQLLSTPHLRAVLMVHDTVAQKNFDPVLPPLPDNIDEDFEEESVKIVRLVKNKEPLG----------ATIRRDEHSGAVVVARIMRGGAADRSGLVHVGDELREVNGITVLHKRPDEISQILAQSQGSITLKIIPATQEEDRFKESKVFMRALFHYDPREDRAIPCQEAGLPFQQRQVLEVVSQDDPTWWQAKRVGDTNLRAGLIPSKQFQERRLSYRRTTGTIPSPQNLRKPLYDQPCDKETCDCDGYFKGH------------------------YVAGLRRSFRLGCRERLTGSQEVKVPVGAESQVLLTYEEVARYQHQPGERSRLVVLIGSLGAHLHELKQRVVAEDPQHFGVAVPHTTRPRKSHEREGVEYHFVSKQAFEADIQHNKFLEHGEHKENLYGTSLEAIQTVMAKNKVCLVDVEPEALRHLRTPEFKPYVIFVKP---AIQE--KRKTPPVSPDSEDPA-TPLDEQQQEMAASAAFIDQHYGHLIDTVLVRQDLQSVCSQLRAVIESLSKDTYWVPISWVR-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88910-1", "uniprot_id": "MPP3_MOUSE", "id": "O88910-1", "name": "MAGUK p55 subfamily member 3", "aln": "----MPVLSEDSGLHETLALLTSQLRPDSNHR--EEMGFLRDVFSEKSLSYLMKIHEKLRYYERQS-PTPVLHSAMALAEDVMEEL-QAASVHSDERELLQLLSTPHLRAVLMVHDTVAQKNFDPVLPPLPDNIDEDFEEESVKIVRLVKNKEPLG----------ATIRRDEHSGAVVVARIMRGGAADRSGLVHVGDELREVNGIAVLHKRPDEISQILAQSQGSITLKIIPATQEEDRFKDSKVFMRALFHYDPREDRAIPCQEAGLPFQRRQVLEVVSQDDPTWWQAKRVGDTNLRAGLIPSKQFQERRLSYRRTTGTLPSPQNFKKPPYDQPCDKETCDCDGYFKGH------------------------YVAGLRRSFRLGCRERLGGSQEAKVPTGAESQVLLTYEEVARYQHQPGERPRLVVLIGSLGAHLHELKQRVVAEDPQQFAVAVPHTTRPRKSHERDGVEYHFVSKQAFEADVHHNKFLEHGEYKENLYGTSLEAIQAVMAKNKVCLVDVEPEALRHLRTPEFKPYVIFVKP---AIQE--RRKTPPVSPDSEDIA-SSLDEQQQEMAASAAFIDQHYGHLIDTVLVRQDLQEPAASS-----ELS-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13368-1", "uniprot_id": "MPP3_HUMAN", "id": "Q13368-1", "name": "MAGUK p55 subfamily member 3", "aln": "----MPVLSEDSGLHETLALLTSQLRPDSNHK--EEMGFLRDVFSEKSLSYLMKIHEKLRYYERQS-PTPVLHSAVALAEDVMEEL-QAASVHSDERELLQLLSTPHLRAVLMVHDTVAQKNFDPVLPPLPDNIDEDFDEESVKIVRLVKNKEPLG----------ATIRRDEHSGAVVVARIMRGGAADRSGLVHVGDELREVNGIAVLHKRPDEISQILAQSQGSITLKIIPATQEEDRLKESKVFMRALFHYNPREDRAIPCQEAGLPFQRRQVLEVVSQDDPTWWQAKRVGDTNLRAGLIPSKGFQERRLSYRRAAGTLPSPQSLRKPPYDQPCDKETCDCEGYLKGH------------------------YVAGLRRSFRLGCRERLGGSQEGKMSSGAESPELLTYEEVARYQHQPGERPRLVVLIGSLGARLHELKQKVVAENPQHFGVAVPHTTRPRKSHEKEGVEYHFVSKQAFEADLHHNKFLEHGEYKENLYGTSLEAIQAVMAKNKVCLVDVEPEALKQLRTSEFKPYIIFVKP---AIQE--KRKTPPMSPACEDTA-APFDEQQQEMAASAAFIDRHYGHLVDAVLVKEDLQGAYSQLKVVLEKLSKDTHWVPVSWVR-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "X1WFJ8-1", "uniprot_id": "X1WFJ8_DANRE", "id": "X1WFJ8-1", "name": "", "aln": "MKEAMPVLSAGGGLHETLALLTSQLRPDANHK--EDMVFLRDVFSERSLSCLMKIHEKLRQYEKQS-PTPVLHSASTLAEDVAEEL-QSGPMSVEEKELLHLLTSPHLKAVLSVHDTVAQKNFDPVLPPLPDDFEDELDEESVKIVRLVKNKEPLG----------ATIRRDESTGAVIVARIMKGGAADRSGLVHVGDELREVNGSSVMHKRPDEISQLLSQSQGSITLKIIPAIKEEDKLQENKVYMRALFDYTPLEDKATPCQEAGLPFKRGDVLQVVSQDDQTWWQAKRIGDCNLRAGLVPSKQFQERRLAYRIKMGTLQNSKSPKKAVYDQGCDKEDCDCEGYFNGQ------------------------YIAGLRRSFRLSRKDRRGSSGEANVSDQNDT-DFLTYEEVTRYQQRSNERPRLVVLIGSLGARINELKQKVIAENPHRYAVAVPHTTRPKKSHEKEGVEYHFVTKQAFDADAQNNKFIEYGEYKENLYGTSIEAIRSVQAKNKMCLVDVQPEALKALRTAEFKPYVIFVKP---KIPESRRRRSAATSPGGGEHG-RITEEDLQEMRLSAQQIDQQYGHLVDRVLIKEDTASASTELRSILERLERETFWVPISWVRP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32U0N5-1", "uniprot_id": "A0AB32U0N5_DANRE", "id": "A0AB32U0N5-1", "name": "", "aln": "----MPVLSPTTGLHEMLALLTSQLHPEANHK--EDLVFLREVFSERSLSYLMKIHERLRQFHLYS-PTPVLHSASCLAEDVAEEL-QNGSLEEDERELLALLSTPHIKAVLTVHDTVAQKNFEPVLPPLPNDLEDELEEESVKIVRLVKNKEPLG----------ATIRRDEVTGAVVVARIMRGGAADRSGLVHVGDELREVNGNLIIHKRPEEISQILSQSQGSITLKIIPAIKEEDRFKESKVYLRALFDYTPYEDRATPCQEAGLPFLCGDVLQVVSQDDPTWWQAKRVGDSNLRAGLIPSRQFQERRLLYRMKMGTHQSPKSPRATPCDQTCEKEDCDSESSVSGQHVVVVSPKCKAVAPSCGQAFSWEFYSAGLRRSFRLSRKDHQGSNKESHTPESTEN-EFLIYEEVTLHQMRLQDKPRLVVLIGSLGARINELKQKVIAENPQRYGVAVPHTTRPRKSHEKEGVEYHFISKQAFDADIQSNKFIEYGEYKNNQYGTSLESIRSVLARNKVCLVDVQPEALKILRTSEFKPYVIFVKP---RIPEIRRHRSSPTSPERGDNG-HITEEDLLDMKHSAEQMEQQYGHLVDRVLIKEDSASACVELRLILERLEREPQWVPVSWVRS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z8G0-1", "uniprot_id": "A1Z8G0_DROME", "id": "A1Z8G0-1", "name": "", "aln": "--MLEAVMASDINWDPALSKLISTLKESENLSNDQEIDFLKALLESKELNALVNVHTKVAKVGRDDRLAPVLSTSAQVLYEVLEQLSQHCHLNDDCKEAFHLLQDSHLQHLLFAHDAIAQKDFYPHLPEAPVEMDE--DEETIKIVQLVKSNEPLTGAQSTEPIVGATIKTDEESGKIIIARIMHGGAADRSGLIHVGDEVIEVNNINVEGKTPGDVLTILQNSEGTITFKLVPADNK-GAQRESKVRVRAHFDYNPDVDPYIPCKEAGLAFQRGDVLHIVAQDDAYWWQARKEHERSARAGLIPSRALQERRILHDRTQKNGTDLDS-KPGSCASLCTTPPGSPRLPASSS-----------------------------TSSCRQPKTKKIMYDLTENDDFDREQ--IATYEEVAKLYPRPG-VFRPIVLIGAPGVGRNELRRRLIARDPEKFRSPVPYTTRPMRTGEVAGREYIFVAREKMDADIEAGKFVEHGEYKGHLYGTSAESVKSIVNAGCVCVLSPHYQAIKTLRTAQLKPFLIHVKPPELDILKATRTEARAKSTFDEANARSFTDEEFEDMIKSAERIDFLYGHFFDVELVNGELVNAFEQLVQNVQRLENEPVWAPSMWVQ-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .*:: . . *: * * *: . * ::: **: ::..:.*. *:::* :: . :*** :: : :* *:* * : : :* : ** .*:: :* .**::***:* * ** * :::: :**::***:***.:*** ***: ** :* :::****:*********:*****: ***. : * * :: :* :*:*:**:*::** :: . ::.** :** *.* * * **:****.* :**.:*:*** ****:: : . ****:**: :****: : . . .. : . * . . .. * * .: . : : : ****: : * :****: *. :**:::::*.:*.:: .**:**** :: * * ** *:::: ::** . .**:*:**:* : **** *::::: . :*::. . :*:: ***.::**::*.*** * : : .: . *. . :*: :* ** :: ***:.* *:. : . *. ", "identical_positions": 180, "similar_positions": 182, "identity": "28.39%" }, { "cls_id": "homologset.agr.MGI:1328355", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9PT53-1", "uniprot_id": "E9PT53_RAT", "id": "E9PT53-1", "name": "Wolframin", "aln": "MEGGRGPAQTPPPSQGRAECRAARSACSAGRCNLR---------GFGGTSRRAGRPSTAAGKMSSGTPPPSPSGPPPPPAPQP---------------QARARLNATTSLEQDKIEP-------PRAPRPQPDSSAGRSAGEATTPEPWAPHASSR-------------------EGTDKAGPMKADVEIPFEEILEKAKAGDPKAQTEVGKHYLRLANDADEELNSCSAVAWLILAAKQGRREAVKLLRRCLADRKGITSENEAEVKQLSSETDLERAVRKAALVMYWKLNPKKKKQVAVSELLENVGQVNEQDGGAQPGPVPKSLQKQRRMLERLVSSESKN-YIALDDFVELTKKYAKGII------PNNLFLQDE------------DEDEDELSGKSPE----------------------------DLPLRQKVVKYPLHAIMEIKEYLIDVASKAGMHWLSTIVPTHHINALIFFFIISNLTIDFFAFFIPLVVFYLSFVSMVICTLKVFQDSKAWENFRTLTDLLLRFEP-NLDVEQAEVNFGWNHLEPYIHFLLSVVFVIFSFPLASKDCIPCSELAVVS-AFFTVTSYMSLSSSAEPYTRRALVTEVAAGLLSLLP-----TMPVDWPFLKALGQTFFTVPIGHFIILNVSLPCLLYVYLFYLFFRMAQLRNFKGTYCYLVPYLVCFMWCELSVVILLQSTGLGLVRASIGYFLFLFALPIL-VAGLALMGTVQFARWFLSLDLTKIMVTTVICSVPLLFRWWTKAN------FSVVGMVKSLTRSSIVKLILVWLTAILLFCWFYVYRSEGMKVYNS-TLTWQQYGFLCGPRAWKETNMARTQILCSHLEGHRVTWTGRFKYVRVTEIDNSAESAIN-MLPFFLGDWMRCLYGEAYPSCSSGN----------------------TSTAEEELCRLKQLAKHP--CHIKKFDRYKFEITVGMPFGT--NGNRGHEEDDITKDIVLRASSEFKDVLLNLRQGSLIEFSTILEG-RLGSKWPVFELKAISCLNCMTQLSPARRHVKIEQD-----WRSTVHGALKFAFDFFFFPFLSAA---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P56695-1", "uniprot_id": "WFS1_MOUSE", "id": "P56695-1", "name": "Wolframin", "aln": "--------------------------------------------------------------MNSGTPPPSPSGPPPPPAPQP---------------QARARLNATASLEQDKIEP-------PRAPRPQADPSAGRSAGEAAAPEPRAPQTGSR-------------------EETDRAGPMKADVEIPFEEVLEKAKAGDPKAQTEVGKHYLRLANDADEELNSCSAVAWLILAAKQGRREAVKLLRRCLADRKGITSENEAEVKQLSSETDLERAVRKAALVMYWKLNPKKKKQVAVSELLENVGQVNEQDGGAQPGPVPKSLQKQRRMLERLVSSESKN-YIALDDFVELTKKYAKGII------PTNLFLQDE------------DEDEDELAGKSPE----------------------------DLPLRQKVVKYPLHAIMEIKEYLIDVASKAGMHWLSTIVPTHHINALIFFFIISNLTIDFFAFFIPLVVFYLSFVSMVICTLKVFQDSKAWENFRTLTDLLLRFEP-NLDVEQAEVNFGWNHLEPYIHFLLSVVFVIFSFPLASKDCIPCSELAVIS-TFFTVTSYMSLSSSAEPYTRRALVTEVAAGLLSLLP-----TVPVDWRFLKVLGQTFFTVPVGHFIILNVSLPCLLYVYLFYLFFRMAQLRNFKGTYCYLVPYLVCFMWCELSVVILLQSTGLGLVRASIGYFLFLFALPIL-VAGLALMGTVQFARWFLSLDLTKIMVTTVICGVPLLFRWWTKAN------FSVMGMVKSLTKSSMVKLILVWLTAILLFCWFYVYRSEGMKVYNS-TLTWQQYGFLCGPRAWKETNMARTQILCSHLEGHRVTWTGRFKYVRVTEIDNSAESAIN-MLPFFLGDWMRCLYGEAYPSCSSGN----------------------TSTAEEELCRLKQLAKHP--CHIKKFDRYKFEITVGMPFGT--NGNRGHEEDDITKDIVLRASSEFKDVLLNLRQGSLIEFSTILEG-RLGSKWPVFELKAISCLNCMTQLSPARRHVKIEQD-----WRSTVHGALKFAFDFFFFPFLSAA---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O76024-1", "uniprot_id": "WFS1_HUMAN", "id": "O76024-1", "name": "Wolframin", "aln": "--------------------------------------------------------------MDSNTAPLGPSCPQPPPAPQP---------------QARSRLNATASLEQERSER-------PRAPGPQAGPGPG-VRDAAAPAEPQAQHTRSR-------------------ERADGTGPTKGDMEIPFEEVLERAKAGDPKAQTEVGKHYLQLAGDTDEELNSCTAVDWLVLAAKQGRREAVKLLRRCLADRRGITSENEREVRQLSSETDLERAVRKAALVMYWKLNPKKKKQVAVAELLENVGQVNEHDGGAQPGPVPKSLQKQRRMLERLVSSESKN-YIALDDFVEITKKYAKGVI------PSSLFLQD-------------DEDDDELAGKSPE----------------------------DLPLRLKVVKYPLHAIMEIKEYLIDMASRAGMHWLSTIIPTHHINALIFFFIVSNLTIDFFAFFIPLVIFYLSFISMVICTLKVFQDSKAWENFRTLTDLLLRFEP-NLDVEQAEVNFGWNHLEPYAHFLLSVFFVIFSFPIASKDCIPCSELAVIT-GFFTVTSYLSLSTHAEPYTRRALATEVTAGLLSLLP-----SMPLNWPYLKVLGQTFITVPVGHLVVLNVSVPCLLYVYLLYLFFRMAQLRNFKGTYCYLVPYLVCFMWCELSVVILLESTGLGLLRASIGYFLFLFALPIL-VAGLALVGVLQFARWFTSLELTKIAVTVAVCSVPLLLRWWTKAS------FSVVGMVKSLTRSSMVKLILVWLTAIVLFCWFYVYRSEGMKVYNS-TLTWQQYGALCGPRAWKETNMARTQILCSHLEGHRVTWTGRFKYVRVTDIDNSAESAIN-MLPFFIGDWMRCLYGEAYPACSPGN----------------------TSTAEEELCRLKLLAKHP--CHIKKFDRYKFEITVGMPFSSGADGSRSREEDDVTKDIVLRASSEFKSVLLSLRQGSLIEFSTILEG-RLGSKWPVFELKAISCLNCMAQLSPTRRHVKIEHD-----WRSTVHGAVKFAFDFFFFPFLSAA---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7TF70-1", "uniprot_id": "A0A8N7TF70_DANRE", "id": "A0A8N7TF70-1", "name": "", "aln": "MDLNANPPSSPETSKEKSATHKRLNPPVPATKSIPGTETAGPPLSKSGSLEKTSPSSTLDTKLKHGSVKTSKVPAKPTPEKQPTPASSHIISKPVPSMQAPTSSKTTQPILSSPNEPSAPSIAISADPPPPTAPPEGLTSTTKTPASDSGKLPRQRSFLAAAQKVMMQEKTRKAEEQAKAEECDDMEDDLPFEELLKKAEAGDPRAQSRLGRYYLKLAEEKDAEKNNLTAVEWLMKAAKQGRRDAAKLLQKCWIQKKGITAENAQEVRCLSSESKFEQAVRRAAMTMYWKLNPDRKKKVAMSEMLENVSQVNTVPGEASVCGVAPSIQTQRKILETMVSNESSSKYVDVEDFVEMTKKFTEGISRTPTLSPSGVYANEEEGILHKSDVARFDKEKNEMAPVTHKRQRKSSWGMRSSGLMLTTRRSDAMRRALDIKAHFLGLQYPLHAIIDMKEHLIDWASRAGVQWLSTIIPTQHVNALIFFFIISNLTIDLFAFAIPLLIFYLSFISMAICTLRVFQSSKGWENFRAFTALLTHFEP-SLDVEQAENNFGWNNLEQYLYFMISVFFVIFTFPVADKGWIPCSELSTVA-IFFTALSYMSLSPSAAAYARKALFIEVASSLCALTS-----RLPKDMVTARMLGQIFTTIPLGESLVLELSVPCVLYIYLFYLFFSMARMRGFRGTYCFLVPYLVCFVWCEFSVVLLRNSTTIGLIRTCVAYFLFLFALPVL-IMGLIALLLIQLIKWFLELELTKMLVTLAVCAVPVTLRLWTRFS------LSILNVFRSITHRGPVKLILLCITTVILLCGVYVYNAEGLKVYNS-TLTWEEYGTLCGPQAWKERGMAQTQLSCSHLEGHRVTWTGIFRYVRVAEKENGAQSVIN-MLPVFMGDWLRCLYGEVYPKCEPLNNTFPIVNVTQVTTGTVNTTILILRQEEEELCRIKAYATHQ--CHVKRFDSYRFEVTVGMPVDG------VTKVDNPAGDILLMASHEFRQVLLNLNPGSMVEFSTKLEG-KLGSKLPAFELKAIHCLNCSSNLVPEGRQVKIERN-----WRKSMLKAIKFAFDFFFAPFLCARINV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IMZ9-1", "uniprot_id": "WFS1_DROME", "id": "Q8IMZ9-1", "name": "Wolframin", "aln": "------------------------------------------------------------------------------------------------------------------------------MATWTQNEPTGVTKRRRWNLEDRASLNKLK-------------------HHIAEEGCPQMQYDLAKELLDNSIVEPN-------------LAKGNQSQK----AVNWLVSAAHNGHEDAVKLLRQCYNDGSGITAENTDEVRRCLAMTPGERAARKAARELFACLS-NGNEHITPKQLERKMRRIYNLQRKRRRRDDDRSSSSSEGEQEPECEPLEDVPTIDLANVERRRLITEAHLVS-----AASNYSAGQMP-----------SVNDALTLSVPD--------------------------------PRSLDHVPCFYRMIFHPLIFFTLFYHRLLNLIVSIP-NVIPLSVRCSVLVAISWWSSRHMLPLVSYYLSLGIMIWATCKMLKTKQQFVDFRIWSGLFLSYGDQNIEADIAEHRFLRNNMKPYLYFFCAFICNLIVYPLVTDAWLPHSELTIISGALTFITMCVSMYASSHQLPDWLVIVSFAVNVLAKYPYEMDEVVSTRWRFLDLRVPTFSSFVIGNGIEFCLNCRTALYLFIPVLLIMMAKRSRWHGVYTFLIPHCVTLSWLQVCIATSQSSTVFGVMRAALGLAGIVLFLPLFGIVALLVPVFVAIDSLGLASEQLRWGSTALACGLVVVLSCILALNRATQKYITMLQLITAITTACLLVLPYMTSSFKDTPRFNAMPRAGLHSLSETNTLPWDRFHALCAQPVHEQPNKIKAQLRCSLLNGMPVIWEGSVTKVEISRVSNFLEDTIANYLPVWLGRMLRCLHGENISQHFKCDP-------------------KLDAQCEEWRSVFKTFNAQSGSCTLQRWNRYEYELLVKVGTKR----SGRLLGRSTTTDVILRAHHDFGNFTRLLSEGDVVLFYGILHNSRLLADNVQVKLKTIECVECRSRDLGTASIERVVAASPMDARLQDLMRGIKYLLNALLNPLITFK---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * . . : . . : ::. * : : : ** : : ** **: **::*:.:*.***::* : ***:** **: : : *:*.*:** :: *. . ::::: :: .:: :: * .... * . .. : : :. . : . . : . .: :: . : * . : :: :: : * . :* : : : :: :: . :**: :***: * .* :::: .: : :** : *: : .::.: ** .* *::: * :*: :.. :: :*:. . :* ***: :: : :*: . : . : ..: .: : . :. * :. :*. : : :. **::: *:: **: ::*.* :*:*: * : * :..:. .** :*::*:.:. ::: **:: : .* : : : : * *.: : : . :::: :. ::* : * : : : .: .: :: **.*:.: **. . :: . ::*: ** *:* * * * . *.:: .* :..* **.::* :***:** . : ** . :* : * ::::: *.:*: * : . : *::* * :* .. * *.:: * *.. :* :. .:**:* *::* :. :: . : .:*: :: :: *:: ", "identical_positions": 127, "similar_positions": 287, "identity": "11.64%" }, { "cls_id": "homologset.agr.MGI:1328356", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZXM2-1", "uniprot_id": "D3ZXM2_RAT", "id": "D3ZXM2-1", "name": "Cell cycle checkpoint control protein", "aln": "MKCLITGGNVKVLGKAVHSLSRIGDELYLEPLKDGLSLRTVNSSRSAYACFLFAPLFFQQYQEASPGQDLLRCKILMKSFLSVFRSLATVEKTVEKCCISLSGSNSHLVVQLHCKYGVKKTHNLSFQDCESLQAVFDPASCPHLLRTPARVLAEAVLSFPLALTEVTLGIGRGRRVILRSYQEEEADSTSKAMVTETSIGEEDFQQLHAPEGRAVTFCLKEFRGLLSFAESANLPLTIHFDVPGRPVIFTVEDS-LLDAHFVLATLLEQ------DSCSQDLCSPKPHQPVPQKQPHSTPHSDDFTNDDIDCYMIAMETTVGNESSRAQPSTSLP-PVPQASHDLAPPSEEEEEEAEPSTVPGTPPPKKFRSLFFGSILAP---------------------IHSPQGPNPVLAEDSDGEG-------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z0F6-1", "uniprot_id": "RAD9A_MOUSE", "id": "Q9Z0F6-1", "name": "Cell cycle checkpoint control protein RAD9A", "aln": "MKCLITGGNVKVLGKAVHSLSRIGDELYLEPLKDGLSLRTVNSSRSAYACFLFAPLFFQQYQAASPGQDLLRCKILMKAFLSVFRSLAIVEKSVEKCCISLSGSHSHLVVQLHCKYGVKKTHNLSFQDCESLQAVFDPASCPHLLRTPARVLAEAVLSFPLALTEVTLGIGRGRRVILRSYQEEEADSTSKAMVTETSIGDEDFQQLHAPEGIAVTFCLKEFRGLLSFAESANLPLTIHFDVPGRPVIFTIEDS-LLDAHFVLATLLEQ------DSCSQGPCSPKPHQPVPQKQAHSTPHLDDFTSDDIDCYMIAMETTGGNEGSGAQPSTSLP-PVSLASHDLAPTSEEE---AEPSTVPGTPPPKKFRSLFFGSILAP---------------------VHSPQGPNPVLAEDSDGEG-------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99638-1", "uniprot_id": "RAD9A_HUMAN", "id": "Q99638-1", "name": "Cell cycle checkpoint control protein RAD9A", "aln": "MKCLVTGGNVKVLGKAVHSLSRIGDELYLEPLEDGLSLRTVNSSRSAYACFLFAPLFFQQYQAATPGQDLLRCKILMKSFLSVFRSLAMLEKTVEKCCISLNGRSSRLVVQLHCKFGVRKTHNLSFQDCESLQAVFDPASCPHMLRAPARVLGEAVLPFSPALAEVTLGIGRGRRVILRSYHEEEADSTAKAMVTEMCLGEEDFQQLQAQEGVAITFCLKEFRGLLSFAESANLNLSIHFDAPGRPAIFTIKDS-LLDGHFVLATLSDT------DSHSQDLGSPERHQPVPQLQAHSTPHPDDFANDDIDSYMIAMETTIGNEGSRVLPSISLS-PGPQPPKSPGPHSEEEDE-AEPSTVPGTPPPKKFRSLFFGSILAP---------------------VRSPQGPSPVLAEDSEGEG-------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F2Z4U5-1", "uniprot_id": "F2Z4U5_DANRE", "id": "F2Z4U5-1", "name": "Cell cycle checkpoint control protein", "aln": "MDCVATGANVKVLAKAIHSLSRIGEELYLEPVDDGLALRSVNSSRSAFASFQLSPLFFQRYQAPTDQS--FRCKMPIKSVQAVFKSLSSLERSVEKCRIQLNSEKSRLTITLHCKHGLLKTHNLSFQDCESLQAVFDKESCTNVLQAQPRLMVDTVLHFPPSLEEVNLSVSSDR-VWLRNHVEDDADS-SRAMMTELCLSSEEFDHFAISSQTSITFCLKELRGLLGFAESSCLPISMYFDEPGSPVILNVTDS-VLEANFVLATLSE-------DSHSKN------HVNSNTKRPDAEQPPDDFMSDDMDSFLIAMETS-ELPGPSHVPTSPLQ-PINNRKHSASDDEEEE-------ALAERPPNKKFCSLFFGSVLPTPSL------------------TNQTIQSQEVLASDSEDENQTETS--------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O96533-1", "uniprot_id": "RAD9_DROME", "id": "O96533-1", "name": "Cell cycle checkpoint control protein Rad9", "aln": "MKYTLEGSNARVIAKAVQSLSKVGKEMFIEIDQQSLQMRAINATQSAVGSISFKRSMFEVYDMPPHSD--FYCKISMKGCLAVFRNMN----EVEYCELNLLDNQTNLQVNLRCKLETTKEATISIIDDQNINTNINTDQMPNIIRGDHKLLTDISNNFNSSEEELTLEANSGS-VVAKNYIEG-ARVNDKFMRTQLKLKPSEFEQYQVTKETVITFCIKEFRAFLLFAECLNASLTLEFDEAGMPFLLKIKKHGEIECLLIMSTLSPDDISFSEDYCQKDLTVQDEDVRAAAAKRKSSVSKPNVTNKRKGSSSEPAAVQPKRRVEETQLESSLDNPLFQFRDSEAPSVQHPRILAEVDTVVLIEDEAEQEALMLAAADAALEASMAPAPEPPNSTEVCFINTDDSQQPKPAKSSSDEDETIPQSPERPNKVLGVLLGLLQGCVSRLKTMLRLDEHLISGYELL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. *.*.:*:.**::***::*.*:::* .:.* :*::*:::** ..: : :*: *: .. . : **: :*. :**:.: ** * :.* . :.* : *:** * .:*: * :.::: :: . .:::: ::: : * : *:.* . . * :.: * * : * *: : .:*:: . :***:**:*.:* ***. ::: ** .* * ::.: . :: ::::** * .:. . : .: :. .. .. . . .* * .. . :. :: : :*::.: .. .. .. . :...:.* ", "identical_positions": 65, "similar_positions": 147, "identity": "14.01%" }, { "cls_id": "homologset.agr.MGI:1328357", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62885-1", "uniprot_id": "U119A_RAT", "id": "Q62885-1", "name": "Protein unc-119 homolog A", "aln": "--------MKVKKGGGGTGPGAEPVPGASNRSVEPTREPGAEAESGSESEPEPGPGPRLGPLQGKQPIGPEDVLGLQRITGDYLCSPEENIYKIDFVRFKIRDMDSGTVLFEIKKPP----------------VSERLPINRRDLDPNAGRFVRYQFTPAFLRLRQVGATVEFTVGDKPVNNFRMIERHYFRNQLLKSFDFHFGFCIPSSKNTCEHIYDFPPLSEELISEMIRHPYETQSDSFYFVDDRLVMHNKADYSYSGTP--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z2R6-1", "uniprot_id": "U119A_MOUSE", "id": "Q9Z2R6-1", "name": "Protein unc-119 homolog A", "aln": "--------MKVKKGGGGTGSGAEPVPGASNRSAEPTREPGAEAESGSESEPEPGPGPRLGPLQGKQPIGPEDVLGLQRITGDYLCSPEENIYKIDFVRFKIRDMDSGTVLFEIKKPP----------------VSERLPINRRDLDPNAGRFVRYQFTPAFLRLRQVGATVEFTVGDKPVNNFRMIERHYFRNQLLKSFDFHFGFCIPSSKNTCEHIYDFPPLSEELISEMIRHPYETQSDSFYFVDDRLVMHNKADYSYSGTP--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13432-1", "uniprot_id": "U119A_HUMAN", "id": "Q13432-1", "name": "Protein unc-119 homolog A", "aln": "--------MKVKKGGGGAGTATESAPGPSGQSVAPIPQPPAESESGSESEPDAGPGPRPGPLQRKQPIGPEDVLGLQRITGDYLCSPEENIYKIDFVRFKIRDMDSGTVLFEIKKPP----------------VSERLPINRRDLDPNAGRFVRYQFTPAFLRLRQVGATVEFTVGDKPVNNFRMIERHYFRNQLLKSFDFHFGFCIPSSKNTCEHIYDFPPLSEELISEMIRHPYETQSDSFYFVDDRLVMHNKADYSYSGTP--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QE32-1", "uniprot_id": "F1QE32_DANRE", "id": "F1QE32-1", "name": "Protein unc-119 homolog A", "aln": "--------MKVKQG--------------------------CDAGVPYTTEED---------LLNSPEITPEDVLGLQKITDNYLCGPEQNVHKIDFTRFKIRDMETGTVLFEITKPP----------------TSETG-EDRMDFEQNAGRFVRYQFTPAFLRLRQVGATVEFTVGDSPINNFRMIERHYFRGQLLKSFDFEFGFCIPSSKNTCEHIYEFPPLSEDIMREMILHPYETQSDSFYFVDNKLVMHNKADYSYNGGP--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9XYQ2-1", "uniprot_id": "UN119_DROME", "id": "Q9XYQ2-1", "name": "Protein unc-119 homolog", "aln": "MSVVGKQLNPVQSSGAGAVTTSSSAAAGSSSSNSGVEANGGSGGSSGAAAAGAGASGDAKRPAESSSVTPDEVLHLTKITDDYLCSANANVFEIDFTRFKIRDLESGAVLFEIAKPPSEQYPEGLSSDETMLAAAEKLSLDDT-ADPNAGRYVRYQFTPAFLNLKTVGATVEFTVGSQPLNNFRMIERHFFRDRLLKTFDFEFGFCFPFSKNTVEHIYEFPNLPPDLVAEMISSPFETRSDSFYFVGNRLVMHNKADYAYDGGNIV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:.. .. : . : *::** * :**.:***..: *:.:***.******:::*:***** *** .:* : : ****:**********.*: **********..*:*********:**.:***:***.****:* **** ****:** *. ::: *** *:**:*******.::*********:*.* ", "identical_positions": 113, "similar_positions": 52, "identity": "42.48%" }, { "cls_id": "homologset.agr.MGI:1328359", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZY51-1", "uniprot_id": "D3ZY51_RAT", "id": "D3ZY51-1", "name": "Plakophilin-1", "aln": "MNHSPLKTALAYECFQDQDNSTLALPSDQKMKTGTSGRQRVQEQVMMTVKRQKSKSSQSSTLSHSNRGSMYDGLVDNYNNYGTTSRSSYFSKFQAGNGSWGYPIYNGTLKREPDNRRFSSYSQMENWSRHYPRGSCATTG---AGSDICFMQKIKASRSEPDLYCDPRGTLRKGTLGGKGQKTTQNRYSFYSTCSGQKAVKKCPVRPPSCTSKQDPVCMPPISCN--KDMSFGHSRASSKICSEDIECSGLTIPK---------AVQYLCSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRSGSTEIQKQLTGLLWNLSSTDELKEELVADALPVLTDRVIIPFSGWCDGNSNMSREVVDPEVFFNATGCLR---------------------NLSSADAG-RQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCILHNLSYRLDAEVPTRYRQLEYNTRNAYTEKSSTG-----CFSNRGDKMMNNNYDCPLPEEETNPKGSSWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSNGMSQLIGIKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPVLHRVMGNQVFPEVTRLLTSHTGNTSNS---EDILSSACYTVRNLMTSQPQMAKQYFSNSMLNNVFNLCRNSASSPKAAEAARLLLSDMWASKELQSVLRQQGFDRNMMGNIAGANNFRNFTSRF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97350-1", "uniprot_id": "PKP1_MOUSE", "id": "P97350-1", "name": "Plakophilin-1", "aln": "MNHSPLKTALAYECFQDQDNSTLALPSDQKMKTGTSGRQRVQEQVMMTVKRQKSKSSQSSTLSHSNRGSMYDGLADNYNNYGTTSRSSYFSKFQAGNGSWGYPIYNGTLKREPDNRRFSSYSQMENWSRHYPRGSCATPG---AGSDICFMQKIKASRSEPDLYCDPRGTLRKGTLGSKGHKTTQNRCSFYSTCSGQKAVKKCPVRPPSCTSKQDPVYVPPISCN--KDLSFGHSRASSKICSEDIECSGLTIPK---------AVQYLCSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTPNKLETRRQNGIREAVSLLRRSGSTEIQKQLTGLLWNLSSTDELKEELVADALPVLTDRVIIPFSGWCDGNSNMSREVVDPEVFFNATGCLR---------------------NLSSADAG-RQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCILHNLSYRLDAEVPTRYRQLEYNTRNAYTEKSSTG-----CFSNRGDKMMNNNYDCPLPEEETNPKGSSWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSNGMSQLIGIKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPVLHRVMGNQVFPEVTRLLTSHTGNTSNS---EDILSSACYTVRNLMTSQPQMAKQYFSNSMLNNVFNLCRNTASSPKAAEAARLLLSDMWASKELQSVLRQQGFDRNMMGNIAGANNLRNFTSRF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13835-1", "uniprot_id": "PKP1_HUMAN", "id": "Q13835-1", "name": "Plakophilin-1", "aln": "MNHSPLKTALAYECFQDQDNSTLALPSDQKMKTGTSGRQRVQEQVMMTVKRQKSKSSQSSTLSHSNRGSMYDGLADNYN-YGTTSRSSYYSKFQAGNGSWGYPIYNGTLKREPDNRRFSSYSQMENWSRHYPRGSCNTTG---AGSDICFMQKIKASRSEPDLYCDPRGTLRKGTLGSKGQKTTQNRYSFYSTCSGQKAIKKCPVRPPSCASKQDPVYIPPISCN--KDLSFGHSRASSKICSEDIECSGLTIPK---------AVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELIADALPVLADRVIIPFSGWCDGNSNMSREVVDPEVFFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAG-RQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSYRLDAEVPTRYRQLEYNARNAYTEKSSTG-----CFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNS---EDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSAS-PKAAEAARLLLSDMWSSKELQGVLRQQGFDRNMLGTLAGANSLRNFTSRF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FBR0-1", "uniprot_id": "E7FBR0_DANRE", "id": "E7FBR0-1", "name": "", "aln": "MMPEPLKSALS---LGNMEDTSLAVPSDIEHRSAQQRVLEQVHTIKKSKSKYRSKSKSVSALATSPTSPEGDSVFYDFKFSPGTSLSG--PSFNRGGNMTNGAMQRQNILRKSTNSRSSSGQQVNSNSGRFDRSIYGFQGSVSTQQKTSNQLYNKSTRSAPDLGFQP----TTNGMSSTGQRSQTSRQTFQRWEKGSQMPSSSYSNGTTLVRMSNSNQVNAVSRRPSSLQSNGESRMSMIRSGQAKDFSGMTLEKPVSDMTMRDAVDCLSSTDENVQLCGASYIQHSTFNDDKAKQEVLTLKGLPLLVDLLGSSSPQVQETVAAALRNAIFKNLPNKQEVQRSGGIKQAAQLLG-DANTETQKHLTGLLWNLSSEDGLKPDLLRTALPALTEKVIEPFSANTVDNANTS---LAPEVFCNATACLR---------------------NLSGSKLANRQSMRNCKGLIDSLMRYTENCITAGMPDNQSLENCVCILHNLTYQLETEMPTLFNKINALASQSHNRSSSSDAGPIICFRLQSQKLKQRGFDYPVMED-NNPEGVGWLFHSKALQFYLNLLSSSERDATLEACCGTLQNLTANEGIVSNFLSQTIVQKLNGMKFITPLLQSTNPALQNSAVALLGNLSKSSQTNKVMAPQSLPQLVGFLNSGLSKKESSPEYDSAMATALRSANTLINADPDTGKNLLNNSLINNLYNMS-LNRDLQKSSKASALLLHNLWSNKNIQSFLKKNGMKKKSFVNEVTSAAFKSHLVID", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 248, "similar_positions": 284, "identity": "32.12%" }, { "cls_id": "homologset.agr.MGI:1328360", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99856-1", "uniprot_id": "ARI3A_HUMAN", "id": "Q99856-1", "name": "AT-rich interactive domain-containing protein 3A", "aln": "MKLQAVMETLLQRQQRARQELEARQQLPPDPPAAPPGRAR-AAPDEDREPESARMQRAQMAALAAMRAAAAGLGHPASPGGSEDGPPGSEEEDAAREGTPGSP---GRGREGP----GEEHFEDMASDED-MKPKWEEEEMEEDLGEDEE-------------------------------------------EEEEDYEDEEEEEDEEGLGPPGPASLG-TTALFPRKAQPPQAFRGDGVPRVLGGQERPGPGPAHPGGAAHVAP-QLQPPDHGDWTYEEQFK---QLYELDGDPKRKEFLDDLFSFMQKRGTPVNRIPIMAKQVLDLFMLYVLVTEKGGLVEVINKKLWREITKGLNLPTSITSAAFTLRTQYMKYLYPYECEKRGLSNPNELQAAIDSNRREGRRQSFG--------------------GSLFAYSPGGAHGMLSSPKLPVSSLGLAASTNGSSITPAPKIKKEEDSAI-PITVPGRLPVSLAGHPVVAAQAAAVQAAAAQAAVAAQAAALEQLREKLESAEPPEKKMALVADEQQRLMQRALQQNFLAMAAQLPMSIRINSQASESRQDS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AVNLTGTNGSNSISMSVEINGIMYTGVLFAQPPAPTPTSAPNKGGGGGGGSSSNAGGRGGNTG--TSGGQAGPAGLSTPSTS-TSNNSLP-------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q62431-1", "uniprot_id": "ARI3A_MOUSE", "id": "Q62431-1", "name": "AT-rich interactive domain-containing protein 3A", "aln": "MKLQAVMETLIQRQQRARQELEARQAPPPPPPEPTGVRARTTMTDEDREPENARMHRTQMAALAAMRAAAAGLGHPSSPGGSEDGPPISGDEDTAREGTLSSPALHGSVLEGAGHAEGDRHLMDVGSDDDDTKSKWEEQELEE-LGEEEE-------------------------------------------EEEEEDDFEEEEEEEEGLGPPESASLG-TAGLFTRKAPPAQAFRGDGGPRMLSGPERLGPGPAHP---SHMAS-QMPPPDHGDWTFEEQFK---QLYELDADPKRKEFLDDLFSFMQKRGTPVNRIPIMAKQVLDLFMLYVLVTEKGGLVEVINKKLWREITKGLNLPTSITSAAFTLRTQYMKYLYPYECERRGLSSPNELQAAIDSNRREGRRQSFG--------------------GSLFAYSPSGAHSMLPSPKLPVTPLGLAASTNGSSITPAPKIKKEEDSAI-PITVPGRLPVSLAGHPVVAAQAAAVQAAAAQAAVAAQAAALEQLREKLESTEPPEKKMALVADEQQRLMQRAVQQSFLAMTAQLPMNIRINSQASESRQDS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AVSLTSANGSNSISMSVEMNGIVYTGVLFAQPPPPTAPSAPGKGGVSSIGTNTTTGSRTGASGSTVSGGQVGLPGVSTPTMSSTSNNSLP-------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0N4STX9-1", "uniprot_id": "A0A0N4STX9_DANRE", "id": "A0A0N4STX9-1", "name": "AT-rich interactive domain-containing protein 3", "aln": "MKLQAVMEN-LHRQQRAKLLMEQAGQSHNPAP----------IGEELKSISASDTEQAQMAALAAMRAVAAGLQRLDSP-VSEHSSEGDEDDEEEDEEE------------------GEDQYKDMMGSEE-------EEQIKQKFDEDDF-------------------------------------------EEE---DYDEELGDEGLPSGREAVTPGRGILLLPHRQLQPHSLMLKARP----GSESEARALTHS---AHSSQGPLHGQDHADWTYEEQFR---QLYELDSDPKRKEFLDDLFSFMQKKGTPVNRIPIMAKQVLDLYMLYQLVTEKGGLVEVINKKLWREITKGLNLPTSITSAAFTLRTQYMKYLYTYECEKRALSNPNELKAAIDSNRREGRRQGFG--------------------NSLFTYSPNGTPTMLSSPKRTMSSMGIALPSNGASISSIQNIKKEDD------GFQTRLPASLATHSVAAAQ-----AAAAQAATIAQVAALEQLRDNLETGEPPRKKIALPLEEHQRLLQRALQHNLMAMTAQIPMNIRINNQ--ESRPDS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AMNLT-TNGLNSISMSLELNGVVYTGVLFAQSVAQTSLGASNK-----------------------STGNSGPQSVLHTPTSSSSNNQSP-------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A2BEA6-1", "uniprot_id": "ARI3A_DANRE", "id": "A2BEA6-1", "name": "AT-rich interactive domain-containing protein 3A", "aln": "----MVDNTSIATKSALQAAFSSASSLPLLVSSPGAHGQSGGGGGMKLEAVMENLQRQQAARLALEEKLRQAEKEKDIRSMVESQIQQQALAFRHYQAAVRGAFAAGVPNSSSGHPLERRAESDIDDEDD----EDDDPELDRGMDDEER-------------------------------------------DMDEDDSMNEGGGDEDLEGPLAHYPPR--HAVYPGAGQSP-----KSTPIHLSRVQPPYPAPRQAE--SPSALAPQAQSQHHEWTYEEQFK---QLYELDDDEKRKEFLDDLFSFMQKRGTPVNRIPIMAKQVLDLYTLYKLVTEKGGLVEVINKKIWREITKGLNLPTSITSAAFTLRTQYMKYLYPYECEKRGLSSPGELQAAIDSNRREGRRQSYG--------------------STLFNYSPVGTPTLLASPKLQMPHISMPTP-NGGHMTQTPGIKKEDSMLSSCLTNRVGIPMSLAGHHS---------AAQAAAAAAVQAAALEQLREKLESGEPPEKKVMLMAEEQQRIMQHALQQNLFAMATQLPMNIKLNNR--DDRQET----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALNLS-TNGISSINMSIEINGVVYTGVLFARKPAIGFMPSSQR--------VHHQHSSQGKSNSPGLSSHIQPSSSASSSASSHGPATSP-------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24573-1", "uniprot_id": "DRI_DROME", "id": "Q24573-1", "name": "Protein dead ringer", "aln": "--MQLRVHPTMDCSGRSTSNIERDSDLGDDLSHGDRTDDEMRDCDSVDGEHHQLSAKAAIAARLSHTVSGGGGSFASPEPQTELPLSHHHQLPPNHPLNALGSFMGIGGLHSIPNLQHSDVLEKLKMQVRDMKVGLMEQDYAAAAHAAAFGANMLPTTISSGFPLPHNSVAFGHVTSSPSGGNGSSYNGGTTPTNSSNSNATTNGGGTAGPGGTGGSGGGGGGGGGGGGGVGGHQFSFASPTAAPSGKEARHFAANSASNSSTSSEASNSSQQNNGWSFEEQFKQVRQLYEINDDPKRKEFLDDLFSFMQKRGTPINRLPIMAKSVLDLYELYNLVIARGGLVDVINKKLWQEIIKGLHLPSSITSAAFTLRTQYMKYLYPYECEKKNLSTPAELQAAIDGNRREGRRSSYGQYEAMHNQMPMTPISRPSLPGGMQQMSPLALVTHAAVANNQQAQAAAAAAAAHHRLMGAPAFGQMPNLVKQEIESRMMEYLQLIQAKKEQGMPPVLGGNHPHQQQHSQQQQQQQHHHQQQQQQQSQQQHHLQQQRQRSQSPDLSKHEALSAQVALWHMYHNNNSPPGSAHTSPQQREALNLSDSPPNLTNIKREREREPTPEPVDQDDKFVDQPPPAKRVGSGLLPPGFPANFYLNPHNMAAVAAAAGFHHPSMGHQQDAASEGEPEDDYAHGEHNTTGNSSSMHDDSEPQQMNGHHHHQTHHLDKSDDSAIENSPTTSTTTGGSVGHRHSSPVSTKKKGGAKPQSGGKDVPTEDKDASSSGKLNPLETLSLLSGMQFQVARNGTGDNGEPQLIVNLELNGVKYSGVLVANVPLSQSETRTSSPCHAEAPTVEEEKDEEEEEEPKAAEEESHRSPVKQENEDVDQDMEGSEVLLNGGASAVGGAGAGVGVGVPLLKDAVVS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . :. . : * . * .: . : : . . . . . : . . : : :: *::****: ****:: * ***************:***:**:*****.****: ** ** :****:*****:*:** ***:**:******************.****:: **.* **:****.*******..:* . : ** . . .: . . . . : : : . .* . . * :* :.: : : ..:: * :.:: ::. :: . : : *. . : * . : ** .: :.:*:**: *:***.*. . . . . ", "identical_positions": 119, "similar_positions": 108, "identity": "13.03%" }, { "cls_id": "homologset.agr.MGI:1328361", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QZH2-1", "uniprot_id": "BARD1_RAT", "id": "Q9QZH2-1", "name": "BRCA1-associated RING domain protein 1", "aln": "MP------RRPPRVCSGNKPPPVPAMEPATDGLWAHSRAALARLEKLLRCSRCANILREPVCLGGCEHIFCSGCISDCVGSGCPVCHTPAWILDLKINRQLDSMIQLYSKLQNLLHDNKGSDSKDDTSRASLFGDAERKKNSVKMWFSPRSKKIRCVVNKVSVQTQP---QKAKDDKAQEASVFEFVSATPPVVVSTRAKTASRTSAKKHPKKSVAKINREGNFRPETRDSRFDSKEKLKEEKVVSFSQTLVMENSRVN------GEIDLLASGSVVESVFSGSFAEVSLPLAEHIVSPDTVSKSEEAPEKKVCVEDRC-----PVGSDGNPKGCHRPPTSTSKKCGSNVPSASGEIREPTLLAENVVLVDCSSLPSGRLQVDVTLRRQ-SNASDDSLSLSPGTPPSLLNNS-THRQMMSKPSTVKLSSGIPARKRNHRGETLLHIASIKGDISSVEYLLQNGNDPNVKDHAGWTPLHEACSHGHLKIVELLLQHNALVNTTGYHNDSPLHDAAKNGHIDIVKVLLSHGASRNAVNIFGERPVDYTDAENIRSLLLLPEKTDSFSTSQCSVQVNTGQRKSGPLVLIGSGLSSQQQKLLSKLETVLKAKKCAEFDNTVTHVIVPDE-EAQSTLKCMLGILNGCWVLKFDWVKACLDSQEREQEEKYEVPGGPQRSRLNREQLLPKLFDGCYFFLGGNFKHHPKEDLLKLIAAAGGRILSRKPKPDSDVTQTINTVAYHAKPDSDQRFCTQYIVYEDLFNCHPERVRQGKVWMAPSTWLISCVMAFELLPLDS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70445-1", "uniprot_id": "BARD1_MOUSE", "id": "O70445-1", "name": "BRCA1-associated RING domain protein 1", "aln": "MP------RRPPRVCSGNQPAPVPAMEPATDGLWAHSRAALARLEKLLRCSRCANILKEPVCLGGCEHIFCSGCISDCVGSGCPVCYTPAWILDLKINRQLDSMIQLSSKLQNLLHDNK--DSKDNTSRASLFGDAERKKNSIKMWFSPRSKKVRYVVTKVSVQTQP---QKAKDDKAQEASMYEFVSATPPVAVPKSAKTASRTSAKKHPKKSVAKINREENLRPETKDSRFDSKEELKEEKVVSCSQIPVMERPRVN------GEIDLLASGSVVEPECSGSLTEVSLPLAEHIVSPDTVSKNEETPEKKVCVKDLR-----SGGSNGNRKGCHRPTTSTSDSCGSNIPSTSRGIGEPALLAENVVLVDCSSLPSGQLQVDVTLRRK-SNASDDPLSLSPGTPPPLLNNS-THRQMMSSPSTVKLSSGMPARKRNHRGETLLHIASIKGDIPSVEYLLQNGNDPNVKDHAGWTPLHEACSHGHLKVVELLLQHNALVNTPGYQNDSPLHDAVKSGHIDIVKVLLSHGASRNAVNIFGVRPVDYTDNENIRSLLLLPEENESFSTSQCSI-VNTGQRKNGPLVFIGSGLSSQQQKMLSKLETVLKAKKCMEFDSTVTHVIVPDE-EAQSTLKCMLGILSGCWILKFDWVKACLDSKVREQEEKYEVPGGPQRSRLNREQLLPKLFDGCYFFLGGNFKHHPRDDLLKLIAAAGGKVLSRKPKPDSDVTQTINTVAYHAKPESDQRFCTQYIVYEDLFNCHPERVRQGKVWMAPSTWLISCIMAFELLPLDS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99728-1", "uniprot_id": "BARD1_HUMAN", "id": "Q99728-1", "name": "BRCA1-associated RING domain protein 1", "aln": "MPDNRQPRNRQPRIRSGNEPRSAPAMEPDGRGAWAHSRAALDRLEKLLRCSRCTNILREPVCLGGCEHIFCSNCVSDCIGTGCPVCYTPAWIQDLKINRQLDSMIQLCSKLRNLLHDNELSDLKEDKPRKSLFNDAGNKKNSIKMWFSPRSKKVRYVVSKASVQTQP---AIKKDASAQQDS-YEFVSPSPPADVSERAKKASARSGKKQKKKTLAEINQKWNLEAEKEDGEFDSKEESKQKLVSFCSQPSVISSPQIN------GEIDLLASGSLTESECFGSLTEVSLPLAEQIESPDTKSRNEVVTPEKVCKNYLTSKKSLPLENNGKRGHHNRLSSPISKRCRTSILSTSGDFVKQTVPSENIPLPECSSPPSCKRKVGGTSGRKNSNMSDEFISLSPGTPPSTLSSS-SYRRVMSSPSAMKLLPNM-AVKRNHRGETLLHIASIKGDIPSVEYLLQNGSDPNVKDHAGWTPLHEACNHGHLKVVELLLQHKALVNTTGYQNDSPLHDAAKNGHVDIVKLLLSYGASRNAVNIFGLRPVDYTDDESMKSLLLLPEKNESSSASHCSV-MNTGQRRDGPLVLIGSGLSSEQQKMLSELAVILKAKKYTEFDSTVTHVVVPGD-AVQSTLKCMLGILNGCWILKFEWVKACLRRKVCEQEEKYEIPEGPRRSRLNREQLLPKLFDGCYFYLWGTFKHHPKDNLIKLVTAGGGQILSRKPKPDSDVTQTINTVAYHARPDSDQRFCTQYIIYEDLCNYHPERVRQGKVWKAPSSWFIDCVMSFELLPLDS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QKB4-1", "uniprot_id": "A0A8M9QKB4_DANRE", "id": "A0A8M9QKB4-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------MFVPNNKKNMRIWFSPKSRKVRCCIHRPVELNTPNGVQQKKSTASPSSEDLAVFNFSSSSQESGPSTPPRAKMNKKTKKKRIGQNSRQAKAAQRPRTWIRSLQERKKLKLEVINKQWNTGEEADVDAIDETGDEDEKMSSGDDNRKPAKRVFFRLPHSQSEETFKPSQQRNLTPNHEKIVEFKDSEQQ---NSAALSLPDHDQQPIAEISPELNENELLQPSFSRVRKRSSSESLPKQPRITPEPKRRSSGEGAALIEDSSQSLKTFRPTNEKPVLSSLGTHDVLKKSPDVRHKQTCPVYMKRNHKGETALHLAASKGDVEGVRKLLAQGADPNLKDNAGWTPLHEACNVGHLGVVEELLQQGALLNTPGYQNDSPLHDAIRSGHIAVVKLLVERGASQSVLNIFGLRPVDYALTPEMKEVLRVAPEASHLITTSLRP---PASKAAGGVVLIGSELTQTQHKQINRAAQLLGGKQAKAFSSAVTHVVVPDVPIMPSTLTTLHGVLNGCWILNFSWLSCSLQAGSWVKESGYEAGDGPLRARANRGSLLPPLFDGCFFYMLGSFRKPPKDELLQLVKAGGGQLLKRLPKPDSDVTQTLNAAAYHAQAGSDQVLCTQYILYDPQSSYKPQKVRLGKVWSAPSTWLLDCIAAFRLLPVPEP", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .:*:.:::****:*:*:* : : . * *. : . . ... :.. . :. . ** ** :.: .:: : . . . :*. * : .* . . . :: .* : ::**. . : .:. . :*. .*. . : * : . :: : * . . :.: : *. : : . .: *:. :: * . . *.. :: : ..*.. : . ****:*** **:*: ***: .*. ** :* ***:**:**********. *** :** ***: **:**.**:******** :.**: :**:*:. ***:..:**** *****: .::.:* :. : . :: ...: * :*:*** *:. *:* :.. :* .*: *..:****:**. ***. : *:*.***:*:*.*:...* :*. ** ** *:* ** .*** *****:*:: *.*:: *:::*::*: *.**::*.* **********:*:.****:. *** :*****:*: . :*::** **** ***:*::.*: :*.***: . ", "identical_positions": 198, "similar_positions": 208, "identity": "25.0%" }, { "cls_id": "homologset.agr.MGI:1328362", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88700-1", "uniprot_id": "BLM_MOUSE", "id": "O88700-1", "name": "RecQ-like DNA helicase BLM", "aln": "-----------MAAVPLNNLQEQLQRHSARKLNNQPSLSKPKSLGFTFKKKT-SEGDVSVTSVSVVKTPALSDKDVNVSEA--FSFTESPLHKPKQQAKIEGFFKHFPGRQQSKG-TCSEPSLPATVQTAQDTLCTTPKTPTAKKLP--VAVFKKLEFSSSADSLS---DWADMDDFDMSAS-DAFASLAKNP-ATRVSTAQKMKKTKRNFFKPPPRKANAVKTDLTPPSPECLQVDLTKESEEEEEEEEEAEGADCLSRDVICIDNDSASEELTEKDTQESQSLKAHLGAERGDSEKKSHEDEAVFHSVQNTEYFEHNDNDYDIDFVPPSPEEIISTASSSLKCSSMLKDLDDSDKEKGILSTSEELLSKPEEMTTHKSDAGTSKDCDAQQIR-IQQQLIHVMEHICKLVDTVPTDELEALN--CGTELLQQRNIRRKLLAEAGFNGN----DVRLLGSLWR----HRPDSLDNTVQGDSCPVGHPNKELNSPYLLSHSPSTEE--------CLPT---TTPGKTGFSATPKNLFERPLLNSHLQKSFVS-SNWAETPRMEN----------RNESTDFPGSVLTSTTVKAQSKQAASGWNVERHGQASYD---------------------------IDNFNIDDFDDDDDDDDWENIMHNFPASKSSTATYPPIKEGGPVKSLSERISSAKAKFLPVVSTAQNTNLSESIQNCSDK-LAQNLSSKNPKHEHFQSLNFPHTKEMMKIFHKKFGLHNFRTNQLEAINAALLGEDCFILMPTGGGKSLCYQLPACVSPG----VTIVISPLRSLIVDQVQKLTSFDIPATYLTGDKTDSEAANIYLQLSKKDPIIKLLYVTPEKVCASNRLISTLENLYERKLLARFVIDEAHCVSQWGHDFRQDYKRMNMLRQKFPSVPVMALTATANPRVQKDILTQLKILRPQVFSMSFNRHNLKYYVLPKKPKKVAFDCLEWIRKHHPYDSGIIYCLSRRECDTMADTLQREGLAALAYHAGLSDSARDEVQHKWINQDNCQVICATIAFGMGIDKPDVRFVIHASLPKSMEGYYQESGRAGRDGEISHCVLFYTYHDVTRLKRLIMMEKDGNYHTKETHVNNLYSMVHYCENITECRRIQLLAYFGEKGFNPDFCKKYPDVSCDNCCKTK--DYKTKDVTDDVKNIIRFVQEHSSSPGTR---NIGPAGRFTLNMLVDIFLGSKSAKVKSG------IFGKGTTYSRHNAERLFKKLILDKILDEDLYINANDQPIAYVMLGTKAHSVLSGHLKVDFMETENSSSIKKQK--------ALVAK-VSQREEVVKKCLGELTEVCKLLGKVFGVHYFN-IFNTATLKKLAESLSSDPEVLLQIDGVTEDKLEKYGAEVIPVLQKYSEWTVPAEDGSPGA-----RGAPEDTEEE-EEEAP---------VSSHYFANQTRNERKRKKMSATHKPKRRRTSYGG-FRAKGGSTTCRKTTSKSKFYG--VTGSRSASCASQATS--SASRKLGIMAPPKP--VNRTFLRPSYAFS---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZQW1-1", "uniprot_id": "D3ZQW1_RAT", "id": "D3ZQW1-1", "name": "RecQ-like DNA helicase BLM", "aln": "--MFGSPVGWIMAAVPLNNLQEQLQRHSARKLKNQFSISKPKPSGFTFKKKT-PEG-----DVSVVRTPVLSDKDVNMSEA--LSYTEPPLHKPKQQSNIDGFFKNSPGGQQSKE-TCSELSLPEVVQIPQDASCTTPKTPAVKKPH--VAIFKKLEFSSSADSLS---DWADIDDFDVPAS-DAFVSLTRNP-TTRVSTAKKLSSSKRNFFKPPPR-ASAVKADLTPSSPECLQVDLTKEQEEE---------ADCLSRDVICIDTDPASEELLEKDVQEGLSLDARLGTERVDSAKKSHEDKAAFQSPQNALYFEHNDNDYDIDFVPPSPEEIISTASSSLKCSSMLKDLDDSDKEKDILSTSKDLS-KPEEMTTPKSDLGTNEDCDAQQTS-LQQQLIRVMEHICKLVDTVPIDELKALT--CGDKLLQQRDIRRKLLAEAGFNRN----DVNLLGSLWR----HRPDSLDNTVQCDSCPVGHPGKELNSPYLPSHSLSTEE--------CLPT---TASGKTGFSATPKSLSERPPLNSHLQKSFVS-SNWAETPRTES----------RTESTYFPGSVLTSTTVKDESKHVASGRDIEREVQASYD---------------------------IDNFNIDDFDDDDDDD-WENIMHNFSVSKSSTAAYPPIKEGGPVKSLSERISSAKAKFLPVASTAQNKNLSESIQNCSDK-FAQNLSSKNPKHEHFQSLNFPHTKEMMKIFRKKFGLHNFRTNQLEAINAALLGEDCFILMPTGGGKSLCYQLPACVSPG----VTIVISPLRSLIVDQVQKLTSFDIPATYLTGDKTDSEAANIYLQLSKKDPIIKLLYVTPEKVCASNRLISTLENLYERKLLARFVIDEAHCVSQWGHDFRQDYKRMNMLRQRFPSVPVMALTATANPRVQKDILTQLKILRPQVFSMSFNRHNLKYYVLPKKPKKVALDCLEWIRKHHPYDSGIIYCLSRKECDTMADTLQREGLAALAYHAGLSDSARDEVQHKWINQDNCQVICATIAFGMGIDKPDVRFVVHASLPKSVEGYYQESGRAGRDGEISHCVLFYTYHDVTRLKRLIMMEKDGNYHTRETHVNNLYSMVHYCENITECRRIQLLAYFGEKGFNPDFCKKHPDVSCDNCCKTK--DYKTKDVTDDVKNIVRFVQEHSSSPGTR---NIGPAGRFTLNMLVDIFLGSKSAKVQSG------IFGKGSAYSRHNAERLFKKLILDKILDEDLYINANDQPIAYVMLGTKAHSVLSGHLKVDFMETENSSSVKKQK--------AAVAH-VSQRDEAVMKCLGELADVCKLLGKVFGVHYFN-IFNTATLKKLAESLSSDPEVLLQIDGVTEDKLEKYGAEIIPVLQKYAEWTLPAEGGSPGS-----RGSRRSTPEETEEEEA---------VSSHYFANQTRNERKRKKVSASQKPKRRRTSYGGGFRAKGGSTTCRKPSSKSKFSG--VTGSRSASCASQATS--AASRKLGIMAPPKP--VNRPFLRPAYAFS---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P54132-1", "uniprot_id": "BLM_HUMAN", "id": "P54132-1", "name": "RecQ-like DNA helicase BLM", "aln": "-----------MAAVPQNNLQEQLERHSARTLNNKLSLSKPKFSGFTFKKKTSSDNNVSVTNVSVAKTPVLRNKDVNVTED--FSFSEP-LPNTTNQQRVKDFFKNAPAGQETQR-GGSKSLLPDFLQTPKEVVCTTQNTPTVKKSR--DTALKKLEFSSSPDSLSTINDWDDMDDFDTSETSKSFVTPPQSH-FVRVSTAQKSKKGKRNFFKAQLYTTNTVKTDLPPPSSESEQIDLTEEQKDD---------SEWLSSDVICIDDGPIAEVHINEDAQESDSLKTHLEDERDNSEKKKNLEEAELHSTEKVPCIEFDDDDYDTDFVPPSPEEIISASSSSSKCLSTLKDLDTSDRKEDVLSTSKDLLSKPEKMSMQELNPETSTDCDARQIS-LQQQLIHVMEHICKLIDTIPDDKLKLLD--CGNELLQQRNIRRKLLTEVDFNKS----DASLLGSLWR----YRPDSLDGPMEGDSCPTGNSMKELNFSHLPSNSVSPGD--------CLLT---TTLGKTGFSATRKNLFERPLFNTHLQKSFVS-SNWAETPRLGK----------KNESSYFPGNVLTSTAVKDQNKHTASINDLERETQPSYD---------------------------IDNFDIDDFDDD---DDWEDIMHNLAASKSSTAAYQPIKEGRPIKSVSERLSSAKTDCLPVSSTAQNINFSESIQNYTDK-SAQNLASRNLKHERFQSLSFPHTKEMMKIFHKKFGLHNFRTNQLEAINAALLGEDCFILMPTGGGKSLCYQLPACVSPG----VTVVISPLRSLIVDQVQKLTSLDIPATYLTGDKTDSEATNIYLQLSKKDPIIKLLYVTPEKICASNRLISTLENLYERKLLARFVIDEAHCVSQWGHDFRQDYKRMNMLRQKFPSVPVMALTATANPRVQKDILTQLKILRPQVFSMSFNRHNLKYYVLPKKPKKVAFDCLEWIRKHHPYDSGIIYCLSRRECDTMADTLQRDGLAALAYHAGLSDSARDEVQQKWINQDGCQVICATIAFGMGIDKPDVRFVIHASLPKSVEGYYQESGRAGRDGEISHCLLFYTYHDVTRLKRLIMMEKDGNHHTRETHFNNLYSMVHYCENITECRRIQLLAYFGENGFNPDFCKKHPDVSCDNCCKTK--DYKTRDVTDDVKSIVRFVQEHSSSQGMRNIKHVGPSGRFTMNMLVDIFLGSKSAKIQSG------IFGKGSAYSRHNAERLFKKLILDKILDEDLYINANDQAIAYVMLGNKAQTVLNGNLKVDFMETENSSSVKKQK--------ALVAK-VSQREEMVKKCLGELTEVCKSLGKVFGVHYFN-IFNTVTLKKLAESLSSDPEVLLQIDGVTEDKLEKYGAEVISVLQKYSEWTSPAEDSSPGISLSSSRGPGRSAAEELDEEIP---------VSSHYFASKTRNERKRKKMPASQRSKRRKTASSG-SKAKGGSATCRKISSKTKSSS--IIGSSSASHTSQATS--GANSKLGIMAPPKP--INRPFLKPSYAFS---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6YUA3-1", "uniprot_id": "A0A8M6YUA3_DANRE", "id": "A0A8M6YUA3-1", "name": "RecQ-like DNA helicase BLM", "aln": "MTNERASCKYAMSSLPQNNLKEHLERHNN-AAQNKLSLLKPKPGGFCFKKKSSSGISKVEVPQKVTGSSVLANRSVNIPSN--FEVTKNPVTFSQKPERVAPKVNFFTAPSKPKTNTVNPLANPFALNKTPLVQSTIKALPKSAALPKDSTNDQTVELKHDISQLS-FNEWDDLDDFETPVKSRVASPVAGTS-TKKPSVSDQNTSSSCSSKCEETKVNEESQATETITAPKDVLSAANGVSTET---------AEREPEDSPIKKSKRPKKSVQHTALLSDTEDEEIIHCVSPDTNQKNFKSVAVAEKDKWGEPNVIDSDDCEENNHYEGFEDFIPPSPIPEEIS-----LSVSDKEK--SSSEPVTPANKKESSRSASGLPAPLDQSAKGLKGADDALFSVMESICCLVDTIPEHELIALT--CGTELLLQRAHRKRILAKGGSSRTSHSDSVSTPGFLNRPTFGVTPSNLTSLTPVTSGKREGVKTGFSFRKSIASVMSVGDESVFEDSDCIINGVETPGGTWNPNSSTKISAGRDTFNGSIQTLSKPESKTDKCYSRLS----------FNESSNQTDLFYSPKRVDSGSRNADSSVEINIAGSSSLRTGAEPVDD-----------------FLLDDFDIDDFDENDIPDYYEEPPSVLESRNNSGVKTPSVQEGGSSKSFER------KTFTPPAPKSIKTPNPEPLY-------------RNPAHDRFRGFNFPHSPEMMKIFHKKFGLHQFRFNQLEAINASLLGEDTFVLMPTGGGKSLCYQLPACVSAG----VTVVISPLRSLIVDQVQKLTTLDICATSLSGDKKDSEAARIYMQLSRKDPAIKLLYATPEKVCASGRMISALQNLYERGLLARLVIDEAHCVSQWGHDFRPDYKRLHELRRMFPNVPIMALTATATPRVQKDILNQLAMTRPQVFTMSFNRNNLKYSVLPKKPKKVDEECIQWIKKYYPRDSGIVYCLSRNDCDTLADSLQRAGIAALAYHAGLSDSDREYVQNKWINQDGCQVMCATIAFGMGIDKPDVRYVIHASLPKSVEGYYQESGRAGRDGEISHCVLFYSYSDVIRIKRLIAMDKDGNQQSKATHINNLHSMVHFCENVAECRRIQLLAYFGEHTFNTSFCKEHPEVICDNCARPN--KYKSRNVTDDVKKIARFVQDNCEKVGNRYG-KSAQQNRLTLNMLVEIFLGSKSARIQTG------MFGVGAAYSKHNAERLFKKLVLDNVLMEDLYITNSGQAVAYISAGPKAMSVLNGCMQVEFHETESASSIRKHR--------ASVCEKVSKREEMVKKCLGELNDLCKKLGKVFGIHYYN-IFSTATLKKIAETLSADPEVLLQIDGVTEDKLEKYGAEFIELLQKYSEWQLPAEAQAESSGWIDTTRGHQNDEDDNDDDDEG-----GGDVTSTYFRSNSGRGAKRKQGSYSRKPKRRKGSSGQNSSAKGGYSSNWSSSRGGGRGGGYRGGSRGAGRGSRSAPSGSAAKRPGFMSLPTPQAAARPFLKPSFSHL---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VGI8-1", "uniprot_id": "BLM_DROME", "id": "Q9VGI8-1", "name": "RecQ-like DNA helicase Blm", "aln": "------MSKKPVAQRKQLTLSSFIGLDGNSQSQPKSRAASVRSKPPAVYNPIFLDASSSDDETTEISSQSNNGTIATKKSS--RDPRTAKLKKHTYLDLSVSPLAKLSAKKYARDSPKKPTSLDLSVSPLAELLAKKSDRDSPKKPVQNENSYTYRGLSESPVENKSIGDTLRKPPQKERKTSIVWLSDSPEK-KVTQNERKILDSPLQRFSFEDFPNKENGNRHHLLTLPDSPPPPQPVKKPEK---------TMWQNETKTIQDKDSPANPLVSNNLASISTLLDSSRAPNTYKGSSRNLFEDSPEKSGSGE-QGYKLGSAKENEIPTKPATASLERNSVTSSPSPAAPLKPRYSVAFDNSLADYLKDLAQNDNFSIDPNKQNTETLKSTLGFFRNTYVELMEKYCSLIDQIPAMHFNEIAGFQPNTFLKLKVMRQKFKARTQLVQNSLDKKESQLKAEQEALEKEEIEMQAEQAQQTVLSSSSPEKSRPIMPLPKVQEIKDEK--IPNRNQLIHDLCGEPDNFSPPSSPRDTQLIPKRQQLINDLCGEPDDFSPPSKQNDPHLLRKCEELVHDLCEEPDDYLAQSMMLDGDLEEEQLNGPTQGTTTSGMDDDEDDLEGLLAEIEDEHQKMQGRRSEFNGYSYKELEAVKVKEKHKETPINISLDDDGFPEYDEAMFEQMHSQAAANKSRVSSAGPSTSKSVVPTKQTSALHSQKLSGNFHANVHNDGITGEFDGQKFEHSTRLMHGLSYSFGLKSFRPNQLQVINATLLGNDCFVLMPTGGGKSLCYQLPAILTEG----VTIVISPLKSLIFDQINKLASLDICAKSLSGEQKMADVMAIYRDLESQPPMVKLLYVTPEKISSSARFQDTLDTLNSNNYISRFVIDEAHCVSQWGHDFRPDYKKLGVLKKRFPNVPTIALTATATPRVRLDILAQLNLKNCKWFLSSFNRSNLRYRVLPKKGVSTLDDISRYIRSKPQHFSGIIYCLSRKECDETSKKMCKDGVRAVSYHAGLTDTDRESRQKDWLTG-KMRVICATVAFGMGIDKPDVRFVLHYSLPKSIEGYYQEAGRAGRDGDVADCILYYNYSDMLRIKKMLDSDKALQYNVKKIHVDNLYRIVGYCENLTDCRRAQQLDYFGEH-FTSEQCLENRETACDNCINKR--AYKAVDALEHARKAARAVKDLCSG-----------RSRFTLLHIADVLKGSKIKKIIDFNHHKTPHHGVLKDWDKNDVHRLLRKMVIDGFLREDLIFTN-DFPQAYLYLGNNISKLMEGTPNFEFAVTKNAKEAKAAVGSVSDGATSSTADGQSGMREIHERCYTDLLDLCRTIASQRNVTMAS-IMNIQALKSMAETLPITEKDMCSIPHVTKANFDKYGAKLLEITSNYASEKLLMQAVLDEEEEQAAAKQRPSTSGWNNESVDW-----DMAVASQGNANTSG-ASGFNSFRAGKRKKIYKSGASKRYKTSTTSPAARKTTSARGRGG--RAGAKRAESSASSAS--------GWKSKKTGNSFGFDLMPLPGSK----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P35187-1", "uniprot_id": "SGS1_YEAST", "id": "P35187-1", "name": "ATP-dependent helicase SGS1", "aln": "-----------MVTKPSHNLRREHKWLKETATLQEDKDFVFQAIQKHIANKRPKTNSPPTTPSKDECGPGTTNFITSIPASGPTNTATKQHEVMQTLSNDTEWLSYTATSNQYADVPMVDIPASTSVVSNPRTPNGSKTHNFNTFRPHMASSLVENDSSRNLGSRNNNKSVIDNSSIGKQLENDIKLEVIRLQGSLIMALKEQSKLLLQKCSIIESTSLSEDAKRLQLSRDIRPQLSNMSIRIDS--------LEKEIIKAKKDGMSKDQSKGRSQVSSQDDNIISSILPSPLEYNTSSRNSNLTSTTATTVTKALAITGAKQNITNNTGKNSNNDSNNDDLIQVLDDEDDIDCDPPVILKEGAP-HSPAFPHLHMTSEEQDELTRRRNMRSREPVNYRIPDRDDPFDYVMGKSLRDDYPDVE--REEDELTMEAEDDAHSSYMTTRDEEKEENELLNQSDFDFVVNDDLDPTQDTDYHDNMDVSANIQESSQEGDTRSTITLSQN-------KNVQVILSSPTAQSVPSNGQNQIGVEHIDLLEDDLEKDAILDDSMSFSFG-------------RQHMPMSHSDLELIDSEKENEDFEEDNNNNGIEYLS-----------------------------DSDLERFDEER--ENRTQVADIQELDNDLKIITERKLTGDNEHPPPSWSPKIKREKSSVSQKDEEDDFDDDFS-------LSDIVSKSNLSSKTNGPTYPWSDEVLYRLHEVFKLPGFRPNQLEAVNATLQGKDVFVLMPTGGGKSLCYQLPAVVKSGKTHGTTIVISPLISLMQDQVEHLLNKNIKASMFSSRGTAEQRRQTFNLFING--LLDLVYISPEMISASEQCKRAISRLYADGKLARIVVDEAHCVSNWGHDFRPDYKELKFFKREYPDIPMIALTATASEQVRMDIIHNLELKEPVFLKQSFNRTNLYYEVN-KKTKNTIFEICDAVKSRFKNQTGIIYCHSKKSCEQTSAQMQRNGIKCAYYHAGMEPDERLSVQKAWQAD-EIQVICATVAFGMGIDKPDVRFVYHFTVPRTLEGYYQETGRAGRDGNYSYCITYFSFRDIRTMQTMIQKDKNLDRENKEKHLNKLQQVMAYCDNVTDCRRKLVLSYFNED-FDSKLCHKN----CDNCRNSANVINEERDVTEPAKKIVKLVESIQNE-------------RVTIIYCQDVFKGSRSSKIVQANHDTLEEHGIGKSMQKSEIERIFFHLITIRVLQEYSIMNNSGFASSYVKVGPNAKKLLTGKMEIKMQFTISAPNSRPSTSSSFQANEDNIPVIAQKSTTIGGNVAANPPRFISAKEHLRSYTYGGSTMGSSHPITLKNTSDLRSTQELNNLRMTYERLRELSLNLGNRMVPPVGNFMPDSILKKMAAILPMNDSAFATLGTVEDKYRRRFKYFKATIADLSKKRSSEDHEKYDTILNDEFVNRAAASSNGIAQSTGTKSKFFGANLNEAKENEQIINQIRQSQLPKNTTSSKSGTRSISKSSKKSANGRRGFRNYRGHYRGRK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .* : : . : . . .. . . . . : . . . . . . . . : : . . .. . . . :. . . : ::. . : * . : . . : . :. : : : . : . . . . . :: : : .. . . . : .. . . .: : .:: : * * ** ***:.:**:* *:* *:**************** :. * .*:***** **: **:::* . :* *. ::. . : : : :.*:* :** :.:* : ::. * ::*:*:*******:****** ***.: ::: :*.:* :******. :*: **: :* : . : **** ** * * ** .. : ::. :**:** *:..*: : : : *: . ****: * *: * :*:***:************:* * ::*:::******:*******: : *: ::.: *: :: :: :* : . : *.::* :: :*:*:::*** * **.*. * .. * : **** . : :. : .:. : *:. . *.*: ::: **: :: .* .: : .*:: ::: .* * :. . . :*: * : .:: * :..: * .: . : . . : . . . :. .: :: . :* .: : . :. . ::. ::. : . . : . . :. . . . . . :. : . : ", "identical_positions": 171, "similar_positions": 292, "identity": "11.04%" }, { "cls_id": "homologset.agr.MGI:1328363", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QWV9-1", "uniprot_id": "CCNT1_MOUSE", "id": "Q9QWV9-1", "name": "Cyclin-T1", "aln": "------------------------------MEG---ERKNNNKRWYFTREQLENSPSRRFGVDSDKELS----YRQQAANLLQDMGQRLNVSQLTINTAIVYMHRFYMIQSFTQFHRYSMAPAALFLAAKVEEQPKKLEHVIKVAHTCLHPQESLPDTRSEAYLQQVQDLVILESIILQTLGFELTID---HPHTHVVKCTQLVR---------------------------------------ASKDLAQTSYFMATNSLHLTTFSLQYTPPVVACVCIHLACKWSNWEIPVSTDGKHWWEYVDATVTLELLDELTHEFLQILEKTPSRLKRIRN-WRAY-QAAMKTKPD-------------------------------------------------------------------------------------------------------DRGADENTSEQTILNMISQTSSDTTIAGLMSMSTASTSAVPSLPSSEE-------------------------------------------------------SSSSLTSVDMLQGERWLSSQPPFKLEAAQGHRTSESLALIGVDHSLQQDGSSAFGSQKQASKSVPSAKVSLKEYRAKHAEELAAQKRQLENMEANVKSQYAYAAQNLLS-----------------------------------------------------------HDSHSSVILKMPIESSENP-----ERPFL---------------DKADKSALKMRLPVASGD------------------------------------------------------------------------------------------KAVSSKPEEIKMRIKVHSAGDKHNSIEDSVTKSREHKEKQRTHPSNHHHHHNHHSHRHSHLQLPAGPVSKRPSDPKHSSQTSTLAHKTYSLSSTLSSSSSTRKRGPPEETGAAVFDHPAKIAKSTKSS-LNFPFPPLPTMTQLPGHSSDTSGLPFSQPSCKTRVPHMKLDKGPPGANGHNAT-------QSIDYQDTVNMLHSLLSAQGVQPTQAPAFEFVHSYGEYMNPRAGAISSRSGTTD--------KPRPPPLPSEPPPPLPPLPK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LWR1-1", "uniprot_id": "A0ABK0LWR1_RAT", "id": "A0ABK0LWR1-1", "name": "Cyclin-T1", "aln": "------------------------------MEG---ERKNNNKRWYFTREQLENSPSRRFGVDSDKELS----YRQQAANLLQDMGQRLNVSQLTINTAIVYMHRFYMIQSFTQFHRYSMAPAALFLAAKVEEQPKKLEHVIKVAHTCLHPQESLPDTRSEAYLQQVQDLVILESIILQTLGFELTID---HPHTHVVKCTQLVR---------------------------------------ASKDLAQTSYFMATNSLHLTTFSLQYTPPVVACVCIHLACKWSNWEIPVSTDGKHWWEYVDATVTLELLDELTHEFLQILEKTPSRLKRIRN-WRAY-QAAMKTKPD-------------------------------------------------------------------------------------------------------DRGADENTSEQTILNMISQTSSDTTIAGLMSMSAASTGAVPSLPASEE-------------------------------------------------------SSSSLTSVDMLQGERWLSSQPPFKLEASQGHRTSENLALIGVDHSLQHDGSNAFVSQKQTSKSVPSAKVSLKEYRAKHAEELAAQKRQLENMEANVKSQYAYAAQNLLS-----------------------------------------------------------HDSHSSVILKMPIEGSENP-----ERPFL---------------DKADKSALKMRLPVAGGD------------------------------------------------------------------------------------------KAASSKPEEIKMRIKVHSAGDKHNSVEDSVAKSREHKEKQRTHPSNHHHHHNHHSHKHSHLQLPVGPVSKRPSDPKHSSQTSTLAHKTYSLSSTLSSSSSTRKRGPPEETGAAVFDHPAKIAKSTKSSSLNFPFPPLPTMTQLPGHSSDTSGLPFSQPSCKTRVPHVKLDKGPPGANGHNTT-------QSIDYQDTVNMLHSLLSAQGVQPTQPPAFEFVHSYGEYMNPRAAGIS-RSGNTD--------KPRPPPLPSEPPPPLPPLPK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O60563-1", "uniprot_id": "CCNT1_HUMAN", "id": "O60563-1", "name": "Cyclin-T1", "aln": "------------------------------MEG---ERKNNNKRWYFTREQLENSPSRRFGVDPDKELS----YRQQAANLLQDMGQRLNVSQLTINTAIVYMHRFYMIQSFTQFPGNSVAPAALFLAAKVEEQPKKLEHVIKVAHTCLHPQESLPDTRSEAYLQQVQDLVILESIILQTLGFELTID---HPHTHVVKCTQLVR---------------------------------------ASKDLAQTSYFMATNSLHLTTFSLQYTPPVVACVCIHLACKWSNWEIPVSTDGKHWWEYVDATVTLELLDELTHEFLQILEKTPNRLKRIWN-WRAC-EAAKKTKAD-------------------------------------------------------------------------------------------------------DRGTDEKTSEQTILNMISQSSSDTTIAGLMSMSTSTTSAVPSLPVSEE-------------------------------------------------------SSSNLTSVEMLPGKRWLSSQPSFKLEPTQGHRTSENLALTGVDHSLPQDGSNAFISQKQNSKSVPSAKVSLKEYRAKHAEELAAQKRQLENMEANVKSQYAYAAQNLLSH----------------------------------------------------------HDSHSSVILKMPIEGSENP-----ERPFL---------------EKADKTALKMRIPVAGGD------------------------------------------------------------------------------------------KAASSKPEEIKMRIKVHAAADKHNSVEDSVTKSREHKEKHKTHPSNHHHHHNHHSHKHSHSQLPVGTGNKRPGDPKHSSQTSNLAHKTYSLSSSFSSSSSTRKRGPSEETGGAVFDHPAKIAKSTKSSSLNFSFPSLPTMGQMPGHSSDTSGLSFSQPSCKTRVPHSKLDKGPTGANGHNTT-------QTIDYQDTVNMLHSLLSAQGVQPTQPTAFEFVRPYSDYLNPRSGGISSRSGNTD--------KPRPPPLPSEPPPPLPPLPK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B9H0-1", "uniprot_id": "A0A8M2B9H0_DANRE", "id": "A0A8M2B9H0-1", "name": "", "aln": "------------------------------MAASFPSPSQNNNKWYFTREQIENSPSRRAGLDPDKELS----YRQQAANLLQDMGQRLNVSQLTINTAIVYMHRFYMVQSFTRFHRNVIAPAALFLAAKVEEQPRKLEHVIKVTHACLNPQDPSPDTRSDTYLQQAQDLVILESIILQTLGFEITID---HPHTHVVKCTQLVRGENQLLTLNCASYCSVKGTSSTPSSQISRLIMSFPFIVPASKDLAQTSYFMATNSLHLTTFCLQYSPPIVACVCIHLACKWSNWEIPVSTDGKHWWQYVDPTVTLELLDELTHEFLQILEKTPSRLKRTRN-WKAAGQTAKKSKVQ-------------------------------------------------------------------------------------------------------DGDQSE-----AIMNMISMSSSDSTLAGLTSLSAPPTG--SSMDSCAD-------------------------------------------------------EHSAAASAQHWQ--------PPSKEQPTANELHAP-------------------------------AKVSLSEYRAKHADELAAQKRELKNMEASVKQGYATAAQALMNQQ---------------------------------------------------------RKDKHHHHQQTSASDTNNPSPIVLKIPLD---------------ERSERSSIKMRLPVPGQSGGG-----------------------------------------------------------------------------------HSHSSGSSSRGSDQDIKVRIRVPDRRGGSGED--GKSR---EKHRERSNHHHHHHHHHHHSSSSSAGSLSASSSSSSAQKHSAGSSGSSKKLSGDSVRTSSSSMSRKRTHMPDPSSSSTHSSSKVSKSSRNS---FQLPTLP------GVPSHVMPDILPSLHHQGNYSHSKTDKADT--NGHNAAG------QSNEYQDTFDMLNSLLSAQGVQPAQPQIFDYRSQYGEFRYS--------SGARG--------GAQPPPLPSEPPPPLPPLPK-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O96433-1", "uniprot_id": "CCNT_DROME", "id": "O96433-1", "name": "Cyclin-T", "aln": "MSLLATPMPQAATASSSSSASAAASASGIPITANNNLPFEKDKIWYFSNDQLANSPSRRCGIKGDDELQ----YRQMTAYLIQEMGQRLQVSQLCINTAIVYMHRFYAFHSFTHFHRNSMASASLFLAAKVEEQPRKLEHVIRAANKCLPP------TTEQNYAELAQELVFNENVLLQTLGFDVAID---HPHTHVVRTCQLVK---------------------------------------ACKDLAQTSYFLASNSLHLTSMCLQYRPTVVACFCIYLACKWSRWEIPQSTEGKHWFYYVDKTVSLDLLKQLTDEFIAIYEKSPARLKSKLNSIKAIAQGASNRTANSKDKPKEDWKITEMMKGYHSNITTPPELLNGNDSRDRDRDRERERERERDPSSLLPPPAMVPQQRRQDGGHQRSSSVSGVPGSSSSSSSSSHKMPNYPGGMPPDAHTDHKSKQPGYNNRMPSSHQRSSSSGLGSSGSGSQRSSSSSSSSSQQPGRPSMPVDYHKSSRGMPPVGVGMPPHGSHKMTSGSKPQQPQQQPVPHPSASNSSASGMSSKDKSQSNKMYPNAPPPYSNSAPQNPLMSRGGYPGASNGSQPPPPAGYGGHRSKSGSTVHGMPPFEQQLPYSQSQSYGHMQQQPVPQSQQQQMPPEASQHSLQSKNSLFSPEWPDIKKEPMSQSQPQPFNGLLPPPAPPGHDYKLNSHPRDKESPKKERLTPTKKDKHRPVMPPVGSGNSSSGSGSSKPMLPPHKKQIPHGGDLLTNPGESGSLKRPNEISGSQYGLNKLDEIDNSNMPREKLRKLDTTTGLPTYPNYEEKHTPLNMSNGIETTPDLVRSLLKESLCPSNASLLKPDALTMPGLKPPAELLEPMPAPATIKKEQGITPMTSLASGPAPMDLEVPTKQAGEIKEESSSKSEKKKKKDKHKHKEKDKSKDKTEKEERKKHKKDKQKDRSGSGGSKDSSLPNEPLKMVIKNPNGSLQAGASAPIKLKISKNKVEPNNYSAAAGLPGAIGYGLPPTTATTTSASIGAAAPVLPPYGAGGGGYSSSGGSSSGGSSKKKHSDRDRDKESKKNKSQDYAKYNGAGGGIFNPLGGAGAAPNMSGGMGAPMSTAVPPSMLLAPTGAVPPSAAGLAPPPMPVYNKK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P46962-1", "uniprot_id": "CTK2_YEAST", "id": "P46962-1", "name": "CTD kinase subunit beta", "aln": "------------------------------------MPSTFESQLFFSRPFLSKRQIQRAQKNTISDYRNYNQKKLAVFKFLSDLCVQLKFPRKTLETAVYFYQRYHLFNRFETEVCYTVATSCLTLGCKEVETIKKTNDICTLSLRLRNVVK----INTDILENFKKRVFQIELRILESCSFDYRVNNYVHIDEYVIKIGRELS---------------------------------------FDYKLCNLAWVIAYDALKLETILVIPQHSIALAI---LKIAYELLDNKNWSSKRYSLFETDEKSVNEAYFDIVNFYINSFDMCDLQRHLPADLLPIG-----------------------------------------------------------------------------------------------------------------------------VERFMELKKNAGPESGLPQIPDHLLNADPYITITRD----------------------------------------------------------------------------------------------------------------------------------NNVQERRYVLSLELINGESSINSSTRHA---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. :*:. : : :* . .: : . ::.:: :*:..: ::**: : :*:: .: * :*.:.* *..* * :* :.: : : : : :. * :*:: .*: :: * . :*:: : : .*.: ::.:* ::*:* :: : .:. .. * :. : :. :: .* . : ::.. :: : : : : . : . . . :** . . : .. : ::. :. * ", "identical_positions": 27, "similar_positions": 116, "identity": "2.35%" }, { "cls_id": "homologset.agr.MGI:1328364", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P50609-1", "uniprot_id": "FMOD_RAT", "id": "P50609-1", "name": "Fibromodulin", "aln": "MQWASILLLRGLCSLSQGQYEEDSHWWLQYLRNQQSTYYDPYDTYPYETSDPYPYEVEEGPAYAYGAPPPPEPRDCPQECDCPPNFPTAMYCDNRNLKYLPFVPSRMKYVYFQNNQIAAIQEGVFDNATGLLWIALHGNQITSDKIGRKVFSKLRHLERLYLDHNNLTRMPGPLPRSLRELHLDHNQISRVPNNALEGLENLTALYLHHNEIQEVGSSMRGLRSLILLDLSYNHLRRVPDGLPSALEQLYLEHNNVYTVPDSYFRGSPKLLYVRLSHNSLTNNGLATNTFNSSSLLELDLSYNQLQKIPPVNTNLENLYLQGNRINEFSISSFCTVVDVMNFSKLQVLRLDGNEIKRSAMPVDAPLCLRLASLIEI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P50608-1", "uniprot_id": "FMOD_MOUSE", "id": "P50608-1", "name": "Fibromodulin", "aln": "MQWASVLLLAGLCSLSQGQYDEDSHWWIQYLRNQQSTYYDPYDPYPYEPSEPYPYGVEEGPAYAYGAPPPPEPRDCPQECDCPPNFPTAMYCDNRNLKYLPFVPSRMKYVYFQNNQISAIQEGVFDNATGLLWVALHGNQITSDKVGRKVFSKLRHLERLYLDHNNLTRMPGPLPRSLRELHLDHNQISRVPNNALEGLENLTALYLHHNEIQEVGSSMRGLRSLILLDLSYNHLRRVPDGLPSALEQLYLEHNNVYTVPDSYFRGSPKLLYVRLSHNSLTNNGLATNTFNSSSLLELDLSYNQLQKIPPVNTNLENLYLQGNRINEFSISSFCTVVDVMNFSKLQVLRLDGNEIKRSAMPVDAPLCLRLANLIEI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q06828-1", "uniprot_id": "FMOD_HUMAN", "id": "Q06828-1", "name": "Fibromodulin", "aln": "MQWTSLLLLAGLFSLSQAQYEDDPHWWFHYLRSQQSTYYDPYDPYPYETYEPYPYGVDEGPAYTYGSPSPPDPRDCPQECDCPPNFPTAMYCDNRNLKYLPFVPSRMKYVYFQNNQITSIQEGVFDNATGLLWIALHGNQITSDKVGRKVFSKLRHLERLYLDHNNLTRMPGPLPRSLRELHLDHNQISRVPNNALEGLENLTALYLQHNEIQEVGSSMRGLRSLILLDLSYNHLRKVPDGLPSALEQLYMEHNNVYTVPDSYFRGAPKLLYVRLSHNSLTNNGLASNTFNSSSLLELDLSYNQLQKIPPVNTNLENLYLQGNRINEFSISSFCTVVDVVNFSKLQVLRLDGNEIKRSAMPADAPLCLRLASLIEI", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***:*:*** ** ****.**::*.***::***.**********.****. :**** *:*****:**:*.**:*********************************************::**************:***********:*************************************************************:****************************:*************:***************:*******************:****************************************************:*********************.*********.****", "identical_positions": 343, "similar_positions": 29, "identity": "91.22%" }, { "cls_id": "homologset.agr.MGI:1328365", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q64666-1", "uniprot_id": "SNAT_RAT", "id": "Q64666-1", "name": "Serotonin N-acetyltransferase", "aln": "--MLSIHPLKPEALHLPLGTSEFLGCQRRHTLPASEFRCLTPEDATSAFEIEREAFISVSGTCP-LHLDEIRHFLTLCPELSLGWFEEGCLVAFIIGSLWDKERLTQESL-TLHRPGGRTAHLHVLAVHRTFRQQGKGSVLLWRYLHHLGSQPAVRRAVLMCENALVPFYEKFGFQAMGPCAITMGSLTFTELQCSLRCHTFLRRNSGC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88816-1", "uniprot_id": "SNAT_MOUSE", "id": "O88816-1", "name": "Serotonin N-acetyltransferase", "aln": "--MLNINSLKPEALHLPLGTSEFLGCQRRHTLPASEFRCLTPEDATSAFEIEREAFISVSGTCP-LYLDEIRHFLTLCPELSLGWFEEGCLVAFIIGSLWDKERLTQESL-TLHRPGGRTAHLHVLAVHRTFRQQGKGSVLLWRYLHHLGSQPAVRRAVLMCEDALVPFYEKFGFQAVGPCAITVGSLTFTELQCSLRCHAFLRRNSGC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q16613-1", "uniprot_id": "SNAT_HUMAN", "id": "Q16613-1", "name": "Serotonin N-acetyltransferase", "aln": "MSTQSTHPLKPEAPRLPPGIPESPSCQRRHTLPASEFRCLTPEDAVSAFEIEREAFISVLGVCP-LYLDEIRHFLTLCPELSLGWFEEGCLVAFIIGSLWDKERLMQESL-TLHRSGGHIAHLHVLAVHRAFRQQGRGPILLWRYLHHLGSQPAVRRAALMCEDALVPFYERFSFHAVGPCAITVGSLTFMELHCSLRGHPFLRRNSGC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q12447-1", "uniprot_id": "PAA1_YEAST", "id": "Q12447-1", "name": "Polyamine N-acetyltransferase 1", "aln": "--MASSSSTLPLHMYIRPLIIEDL--KQILNLESQGF----PPNERASEEIISFRLINCPELCSGLFIREIEGKE----------VKKETLIGHIMGTKIPHEYITIESMGKLQVESSNHIGIHSVVIKPEYQKKNLATLLLTDYIQKLSNQEIGNKIVLIAHEPLIPFYERVGFKIIAENTNVAKDKNFAEQKWIDMERELIKEEYDN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . * : * :: .* :. * * : :: ** :*. *. *.: **. .:: *:..*:*: :* : **: .*: ... :* :.:: ::::. ..:** *:::*..* .: .*:..:.*:****:..*: :. : . . .* * : : :::.: . ", "identical_positions": 34, "similar_positions": 78, "identity": "16.27%" }, { "cls_id": "homologset.agr.MGI:1328366", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q12824-1", "uniprot_id": "SNF5_HUMAN", "id": "Q12824-1", "name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------MMMMALSKTFGQKPVKFQLEDDGEFYMIG---SEVGNYLRMFRGSLYKRYPSLWRRLATVEERKKIVASSHGKKTKPNTKDHGYTTLATSVTLLKASEVEEILDG----NDEKYKAVSISTEPPTYLREQK---------------------AKRNSQWVPTLPNSSHHLDAVPCSTTINRNRMGRD---------------------------------------KKRTFPLCFDDHDPAVIHEN----------------------------------------ASQPEVLVPIRLDMEIDGQK--LRDAFTWNMNEKLMTPEMFSEILCDDLDLNPLT---FVPAIASAIRQQIESYPTDS-ILEDQS-----DQRVIIKLNIHVGNISLVDQFEWDMSEKENSPEKFALKLCSELGLGGEFVTTIAYSIRGQLSWHQKTYAFSEN-----------------PLPTVEIAIRNTGDADQWCPLLETLTDAEMEKKIRDQDRNTRRMRRLANTAPAW-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8J8YH81-1", "uniprot_id": "A0A8J8YH81_RAT", "id": "A0A8J8YH81-1", "name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------MMMMALSKTFGQKPVKFQLEDDGEFYMIG---SEVGNYLRMFRGSLYKRYPSLWRRLATVEERKKIVASSHGKKTKPNTKDHGYTTLATSVTLLKASEVEEILDG----NDEKYKAVSISTEPPTYLREQK---------------------AKRNSQWVPTLPNSSHHLDAVPCSTTINRNRMGRD---------------------------------------KKRTFPLCFDDHDPAVIHEN----------------------------------------ASQPEVLVPIRLDMEIDGQK--LRDAFTWNMNEKLMTPEMFSEILCDDLDLNPLT---FVPAIASAIRQQIESYPTDS-ILEDQS-----DQRVIIKLNIHVGNISLVDQFEWDMSEKENSPEKFALKLCSELGLGGEFVTTIAYSIRGQLSWHQKTYAFSEN-----------------PLPTVEIAIRNTGDADQWCPLLETLTDAEMEKKIRDQDRNTRRMRRLANTAPAW-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z0H3-1", "uniprot_id": "SNF5_MOUSE", "id": "Q9Z0H3-1", "name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------MMMMALSKTFGQKPVKFQLEDDGEFYMIG---SEVGNYLRMFRGSLYKRYPSLWRRLATVEERKKIVASSHGKKTKPNTKDHGYTTLATSVTLLKASEVEEILDG----NDEKYKAVSISTEPPTYLREQK---------------------AKRNSQWVPTLPNSSHHLDAVPCSTTINRNRMGRD---------------------------------------KKRTFPLCFDDHDPAVIHEN----------------------------------------ASQPEVLVPIRLDMEIDGQK--LRDAFTWNMNEKLMTPEMFSEILCDDLDLNPLT---FVPAIASAIRQQIESYPTDS-ILEDQS-----DQRVIIKLNIHVGNISLVDQFEWDMSEKENSPEKFALKLCSELGLGGEFVTTIAYSIRGQLSWHQKTYAFSEN-----------------PLPTVEIAIRNTGDADQWCPLLETLTDAEMEKKIRDQDRNTRRMRRLANTAPAW-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5U379-1", "uniprot_id": "SNF5_DANRE", "id": "Q5U379-1", "name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1-A", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------MALSKTYGQKPIKFQLEEDGDFYMIG---SEVGNYLRMFRGSLYKRYPSLSRRLATVEERKKIVASSH---------DHGYTTLATSVTLLKASEVEEIFDG----HDEKYKAVSISTEPPAYLREQK---------------------AKRNSQWVPTLPNSSHHLDAVPCSTTINRNRMGRD---------------------------------------KKRTFPLCFDDHDPAVIHEN----------------------------------------ASQQEVLVPIRLDMEIDGQK--LRDAFTWNMNEKLMTPEMFAEILCDDLDLSPLT---FVPAIASAIRQQIESYPTDS-ILDEQM-----DQRVIIKLNIHVGNISLVDQFEWDMSEKENSPEKFALKLCSELGLGGEFVTTIAYSIRGQLSWHQRTYAFSEN-----------------PLPTVEIAIRNTGDADQWCPLLETLTDAEMEKKIRDQDRNTRRMRRLANTAPAW-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24090-1", "uniprot_id": "Q24090_DROME", "id": "Q24090-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------MAL-QTYGDKPVAFQLEEGGEYYYVG---SEVGNYMRHFRGILYKKYPGMTRIVLSNEERKRLAESGLS-----------SHILASSVSLLRAVEVDDIMAG----NDEKYRAVSVNTSDTPVPRESK---------------------SKKQPQYVPTMPNSS-HLDAVPQATPINRNRVHTK---------------------------------------KVRTFPMCFDDTDPTASLEN----------------------------------------AAQKECLVPIRLDMELEGQK--LRDTFTWNKNESMITPEQFAEVLCDDLDLNPLP---FVPAIAQAIRQQIEAFPNDPPILEETC-----DQRVIVKLNIHVGNTSLVDQVEWDMSEKNNNPEEFAIKLCAELGLGGEFVTAIAYSIRGQLSWHCRTYAFSEA-----------------PLSTIDVPFRNPSDADAWAPFLETLTDAEMEKKIRDQDRNTRRMRRLANTTTGW-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P18480-1", "uniprot_id": "SNF5_YEAST", "id": "P18480-1", "name": "SWI/SNF chromatin-remodeling complex subunit SNF5", "aln": "MNNQPQGTNSVPNSIGNIFSNIGTPSFNMAQIPQQLYQSLTPQQLQMIQQRHQQLLRSRLQQQQQQQQQTSPPPQTHQSPPPPPQQSQPIANQSATSTPPPPPAPHNLHPQIGQVPLAPAPINLPPQIAQLPLATQQQVLNKLRQQAIAKNNPQVVNAITVAQQQVQRQIEQQKGQQTAQTQLEQQRQLLVQQQQQQQLRNQIQRQQQQQFRHHVQIQQQQQKQQQQQQQHQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQGQIPQSQQVPQVRSMSGQPPTNVQPTIGQLPQLPKLNLPKYQTIQYDPPETKLPYPTYWSDKKADTDTLLYEQIIQRDKINKYSLIRETNGYDPFSIYGFSNKEYISRLWHTLKYYQDLKNTRMKSITSTSQKIPSASIWGNGYSGYGNGITNTTTRVIPQVEVGNRKHYLEDKLKVYKQAMNETSEQLVPIRLEFDQDRDRFFLRDTLLWNKNDKLIKIEDFVDDMLRDYRFEDATREQHIDTICQSIQEQIQEFQGNPYIELNQDRLGGDDLRIRIKLDIVVGQNQLIDQFEWDISNSDNCPEEFAESMCQELELPGEFVTAIAHSIREQVHMYHKSLALLGYNFDGSAIEDDDIRSRMLPTITLDDVYRPAAESKIFTPNLLQISAAELERLDKDKDRDTRRKRRQGRSNRRGMLALSGTSASNTSMNGVHNTVAAGNASSLPPGEILLPDIADIPRTFRTPVPSTLMPGGVDVGPSVESYELRNTTTYKSRPDRPKPVSPPCYIIDHIPGHSLLLSIKLPGKVNTKEEFAAAPNDTSSGTNAMLPSPESLKTKLNSNIRAGVTIPSIPNPIANHTVTNSPNPTLQPVIPGGAASKSVPTPSLPIAPPVAPHDSEATLLTNSNNGSSNNNTQNT", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q06168-1", "uniprot_id": "SFH1_YEAST", "id": "Q06168-1", "name": "Chromatin structure-remodeling complex subunit SFH1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------MSHQNQLIPQAYISN--FHNRLTNEDDGIPIFTMAQQTRQHKRAK--VVNYAEYDNDLFDEFNMNGSNFNNADTHYKDNAVSHENTPALTNGVTMDGSEYNVLENMNGADSIISNNKYDAG---SNMVVESLSGLNSNNNASNGPSN-----------------KAQAQDIGNAVLPDLQDQHHNPFNILRYPKIRDTFINGK---------------------------------------VVSPYRLNTDQETKANANSG-------------------------------------------EAIMIPITLDIEHMGHT--IKDQFLWNYNDDSISPEEFASIYCKDLDMTSAT---LQTQIANIIKEQLKDLENIAATEIMSD------LHVIINLTCNLQDRFFEDNFQWNLNDKSLTPERFATSIVQDLGLTREFIPLISQSLHETILKIKKDWVDGHLIQDHVPN-----DAAFGYLSGIRLDIDELG--SNWCPRVEILTKEEIQKREIEKERNLRRLKRETDRLSRRGRRRLDDLETTMRM---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . . :: : : : . . : . ::. . . :. * .:. . . . . :. . : *. : . :. : . ::** *::: . ::* : ** *:. :. * * . * : . *.. *::*:: . :: ::* : : : *:.:*::.:.. **.** .: :* * **:. *: *:: : : . : . . : * : :: *::: :::*: ** :* ", "identical_positions": 34, "similar_positions": 104, "identity": "3.76%" }, { "cls_id": "homologset.agr.MGI:1328368", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q641Z4-1", "uniprot_id": "CDK9_RAT", "id": "Q641Z4-1", "name": "Cyclin-dependent kinase 9", "aln": "-----------------------------------------MAKQYDSVECPFCDEVTKYEKLAKIGQGTFGEVFKAKHRQTGQK-VALKKVLMENEKEGFPITALREIKILQLLKHENVVNLIEICRTK-----ASPYNRCKGSIYLVFDFCEHDLAGLLSNVLVKFTLSEIKRVMQMLLNGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLARAFS--------LAKNSQPNRYTNRVVTLWYRPPELLLGERDYGPPIDLWGAGCIMAEMWTRSPIMQGNTEQHQLALISQLCGSITPEVWPNVDK-YELFEKLELVKGQKRKVKDRLKAYVRDPYALDLIDKLLVLDPAQRIDSDDALNHDFFWSDPMPS---------DLKGMLSTHLTSMFEYLAP----------------------------PRRKGSQITQQSTNQSRNPATTNQTEFERVF-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99J95-1", "uniprot_id": "CDK9_MOUSE", "id": "Q99J95-1", "name": "Cyclin-dependent kinase 9", "aln": "-----------------------------------------MAKQYDSVECPFCDEVTKYEKLAKIGQGTFGEVFKAKHRQTGQK-VALKKVLMENEKEGFPITALREIKILQLLKHENVVNLIEICRTK-----ASPYNRCKGSIYLVFDFCEHDLAGLLSNVLVKFTLSEIKRVMQMLLNGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLARAFS--------LAKNSQPNRYTNRVVTLWYRPPELLLGERDYGPPIDLWGAGCIMAEMWTRSPIMQGNTEQHQLALISQLCGSITPEVWPNVDK-YELFEKLELVKGQKRKVKDRLKAYVRDPYALDLIDKLLVLDPAQRIDSDDALNHDFFWSDPMPS---------DLKGMLSTHLTSMFEYLAP----------------------------PRRKGSQITQQSTNQSRNPATTNQTEFERVF-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P50750-1", "uniprot_id": "CDK9_HUMAN", "id": "P50750-1", "name": "Cyclin-dependent kinase 9", "aln": "-----------------------------------------MAKQYDSVECPFCDEVSKYEKLAKIGQGTFGEVFKARHRKTGQK-VALKKVLMENEKEGFPITALREIKILQLLKHENVVNLIEICRTK-----ASPYNRCKGSIYLVFDFCEHDLAGLLSNVLVKFTLSEIKRVMQMLLNGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLARAFS--------LAKNSQPNRYTNRVVTLWYRPPELLLGERDYGPPIDLWGAGCIMAEMWTRSPIMQGNTEQHQLALISQLCGSITPEVWPNVDN-YELYEKLELVKGQKRKVKDRLKAYVRDPYALDLIDKLLVLDPAQRIDSDDALNHDFFWSDPMPS---------DLKGMLSTHLTSMFEYLAP----------------------------PRRKGSQITQQSTNQSRNPATTNQTEFERVF-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7SXE8-1", "uniprot_id": "CDK9_DANRE", "id": "Q7SXE8-1", "name": "Cyclin-dependent kinase 9", "aln": "-----------------------------------------MSKYYDGVEFPFCDEFSKYEKLAKIGQGTFGEVFKAKHRQTGKK-VALKKVLMENEKEGFPITALREIKILQLLKHENVVNLIEICRTKG---EATQFNRYKGSIYLVFDFCEHDLAGLLSNANVKFTLAEIKRVMQMLLNGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLARAFS--------LAKNSQGNRYTNRVVTLWYRPPELLLGERDYGPPIDLWGAGCIMAEMWTRSPIMQGNTEQHQLTLISQLCGSITPEVWPGVDKKYELYQKMELPKGQKRKVKDRLKAYVKDPYALDLIDKLLVLDPAQRIDSDDALNHDFFWSDPMPS---------DLKNMLSTHNTSMFEYLAP----------------------------PRRRG-HMPQQPANQNRNPATTSQSEFDRVF-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O17432-1", "uniprot_id": "O17432_DROME", "id": "O17432-1", "name": "", "aln": "----------MAHMSHMLQQPSGSTPSNVGSSSSRTMSLMEKQKYIEDYDFPYCDESNKYEKVAKIGQGTFGEVFKAREKKGNKKFVAMKKVLMDNEKEGFPITALREIRILQLLKHENVVNLIEICRTK-----ATATNGYRSTFYLVFDFCEHDLAGLLSNMNVKFSLGEIKKVMQQLLNGLYYIHSNKILHRDMKAANVLITKHGILKLADFGLARAFS--------IPKNESKNRYTNRVVTLWYRPPELLLGDRNYGPPVDMWGAGCIMAEMWTRSPIMQGNTEQQQLTFISQLCGSFTPDVWPGVEE-LELYKSIELPKNQKRRVKERLRPYVKDQTGCDLLDKLLTLDPKKRIDADTALNHDFFWTDPMPS---------DLSKMLSQHLQSMFEYLAQ----------------------------PRRSNQMRNYHQQLTTMNQKPQDNSMIDRVW-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P23293-1", "uniprot_id": "BUR1_YEAST", "id": "P23293-1", "name": "Serine/threonine-protein kinase BUR1", "aln": "MSDNGSPAVLPKTEFNKYKIGKVKSTPAIQRDAKTNLTYIKLRKRSSEKVYGCTVFQNHYREDEKLGQGTFGEVYKGIHLETQRQ-VAMKKIIVSVEKDLFPITAQREITILKRLNHKNIIKLIEMVYDHSPDITNAASSNLHKSFYMILPYMVADLSGVLHNPRINLEMCDIKNMMLQILEGLNYIHCAKFMHRDIKTANILIDHNGVLKLADFGLARLYYGCPPNLKYPGGAGSGAKYTSVVVTRWYRAPELVLGDKQYTTAVDIWGVGCVFAEFFEKKPILQGKTDIDQGHVIFKLLGTPTEEDWAVARY---LPGAELTTTNYKPTLRERFGKYLSET-GLDFLGQLLALDPYKRLTAMSAKHHPWFKEDPLPSEKITLPTEESHEADIKRYKEEMHQSLSQRVPTAPRGHIVEKGESPVVKNLGAIPRGPKKDDASFLPPSKNVLAKPPPSKIRELHQNPRPYHVNSGYAKTAIPPPAAPAGVNRYGPNNSSRNNRFSGNSTAPNNSRNPVNRFHPETNVSSKYNKVPLPLGPQSRYQGNSNESRYKNSPNDSRYHNPRYVNKPETNFNRQPQKYSRQESNAPINKNYNPSNGSRNMAGDHHQGSRPSHPQFPISPSQGQHQLTSKPIEKKNGSFKDERAKPDESKEFQNSDIADLY", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . .:*.: *:********:*. . : :: **:**:::. **: ***** *** **: *:*:*:::***: : : . : ::*::: : **:*:* * ::: : :**.:* :*:** *** *::***:*:**:** :.*:********** : . :**. *** ***.***:**:::* ..:*:**.**::**:: :.**:**:*: .* .* :* *: * : *. . * .. * :::*: *: : . *::.:**.*** :*: : * :* :* **:** . . :. : .*.: *: *:: . : . . :.: ", "identical_positions": 122, "similar_positions": 122, "identity": "18.43%" }, { "cls_id": "homologset.agr.MGI:1328787", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9R1V3-1", "uniprot_id": "SMAD5_RAT", "id": "Q9R1V3-1", "name": "SMAD family member 5", "aln": "-------------MTSMASLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSSPGQPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDICEFPFGSKQKEVCINPYHYKRVESPVLPPVLVPRHNEFNPQHSLLVQFRNLSHNEPHMPQNATFPDSFHQPNS-TPFPLSPNSPYPPSPASS-TYPNSPASSGPGSPFQLPADTPPPAYMPPDDQMGQDNSQPMDTSNNMIPQIMPSISSRDVQPVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFTDPANNKSRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNCNFHHGFHPTTVCKIPSSCSLKIFNNQEFAQLLAQSVNHGFEAVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPLNPISSVS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99717-1", "uniprot_id": "SMAD5_HUMAN", "id": "Q99717-1", "name": "SMAD family member 5", "aln": "-------------MTSMASLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSSPGQPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDICEFPFGSKQKEVCINPYHYKRVESPVLPPVLVPRHNEFNPQHSLLVQFRNLSHNEPHMPQNATFPDSFHQPNN-TPFPLSPNSPYPPSPASS-TYPNSPASSGPGSPFQLPADTPPPAYMPPDDQMGQDNSQPMDTSNNMIPQIMPSISSRDVQPVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFTDPSNNKSRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNCNFHHGFHPTTVCKIPSSCSLKIFNNQEFAQLLAQSVNHGFEAVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPLNPISSVS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P97454-1", "uniprot_id": "SMAD5_MOUSE", "id": "P97454-1", "name": "SMAD family member 5", "aln": "-------------MTSMASLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSSPGQPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDICEFPFGSKQKEVCINPYHYKRVESPVLPPVLVPRHNEFNPQHSLLVQFRNLSHNEPHMPQNATFPDSFHQPNN-APFPLSPNSPYPPSPASS-TYPNSPASSGPGSPFQLPADTPPPAYMPPDDQMAPDNSQPMDTSSNMIPQTMPSISSRDVQPVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFTDPSNNKSRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNCNFHHGFHPTTVCKIPSSCSLKIFNNQEFAQLLAQSVNHGFEAVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPLNPISSVS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9W7E7-1", "uniprot_id": "SMAD5_DANRE", "id": "Q9W7E7-1", "name": "SMAD family member 5", "aln": "-------------MTSMSSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEDLEKALSSPGQPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLEVCEYPFGSKQKEVCINPYHYKRVESPVLPPVLVPRHSEFNPQHSLLVQFRNLSHNEPHMPLNATFPESFQQHSGGSSFPISPNSPYPPSPASSGTYPNSPASSGPSSPFQLPADTPPPAYMPPDEQMGQDGSQSMETGSSLAPQNMP---RGDVQPVEYQEPSHWCSIVYYELNNRVGEAYHASSTSVLVDGFTDPSNNKNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDTSIFVQSRNCNYHHGFHPTTVCKIPSGCSLKIFNNQEFAQLLAQSVNHGFEAVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEVHLHGPLQWLDKVLTQMGSPLNPISSVS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P42003-1", "uniprot_id": "MAD_DROME", "id": "P42003-1", "name": "Protein mothers against dpp", "aln": "MDTDDVESNTSSAMSTLGSLFSFTSPAVKKLLGWKQGDEEEKWAEKAVDSLVKKLKKRKGAIEELERALSCPGQPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLELCQYPFSAKQKEVCINPYHYKRVESPVLPPVLVPRHSEFAPGHS-MLQFNHVA--EPSMPHNVSYSNSGFNSHS-----LSTSNTSVGSPSSV--------NSNPNSPYDSLAGTPPPAYSPSED----GNSNNPNDGGQLLDAQMG-----DVAQVSYSEPAFWASIAYYELNCRVGEVFHCNNNSVIVDGFTNPSNNSDRCCLGQLSNVNRNSTIENTRRHIGKGVHLYYVTGEVYAECLSDSAIFVQSRNCNYHHGFHPSTVCKIPPGCSLKIFNNQEFAQLLSQSVNNGFEAVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNAISSVS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:::.***********:*******************:*******:***:*:**:***.*************************************************::*::**.:****************************.** * ** ::**.::: ** ** *.::.:* : . :*.... **:* .*.*.**:: *.****** *.:: ..*: : ...: * ** * *.** .*.**.***** ****.:*....**:*****:*:**..* *** ************************** **********::*********:******:******..***************:****:***************************************:******************* *.*****", "identical_positions": 331, "similar_positions": 79, "identity": "68.96%" }, { "cls_id": "homologset.agr.MGI:1329003", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88626-1", "uniprot_id": "GALR3_RAT", "id": "O88626-1", "name": "Galanin receptor type 3", "aln": "MADIQNISLDS---------PGSVGAVAVPVIFALIFLLGMVGNGLVLAVLLQPGPSAWQEPRSTTDLFILNLAVADLCFILCCVPFQAAIYTLDAWLFGAFVCKTVHLLIYLTMYASSFTLAAVSLDRYLAVRHPLRSRALRTPRNARAAVGLVWLLAALFSAPYLSYYGTVRYGALELCVPAWEDARRRALDVATFAAGYLLPVAVVSLAYGRTLCFLWAAVGPAGAAAAEARRRATGRAGRAMLAVAALYALCWGPHHALILCFWYGRFAFSPATYACRLASHCLAYANSCLNPLVYSLASRHFRARFRRLWPCGRRRHR-HHHRAHRALRRVQPASSGPAGYPGDARPRGWSMEP--RGDALRGGGETRLTLSPRGPQ--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88853-1", "uniprot_id": "GALR3_MOUSE", "id": "O88853-1", "name": "Galanin receptor type 3", "aln": "MADIQNISLDS---------PGSVGAVAVPVVFALIFLLGMVGNGLVLAVLLQPGPSAWQEPGSTTDLFILNLAVADLCFILCCVPFQAAIYTLDAWLFGAFVCKTVHLLIYLTMYASSFTLAAVSVDRYLAVRHPLRSRALRTPRNARAAVGLVWLLAALFSAPYLSYYGTVRYGALELCVPAWEDARRRALDVATFAAGYLLPVTVVSLAYGRTLCFLWAAVGPAGAAAAEARRRATGRAGRAMLTVAALYALCWGPHHALILCFWYGRFAFSPATYACRLASHCLAYANSCLNPLVYSLASRHFRARFRRLWPCGHRRHRHHHHRLHRALRRVQPASSGPAGYPGDARPRGWSMEP--RGDALRGG-ETRLTLSARGPQ--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60755-1", "uniprot_id": "GALR3_HUMAN", "id": "O60755-1", "name": "Galanin receptor type 3", "aln": "MADAQNISLDS---------PGSVGAVAVPVVFALIFLLGTVGNGLVLAVLLQPGPSAWQEPGSTTDLFILNLAVADLCFILCCVPFQATIYTLDAWLFGALVCKAVHLLIYLTMYASSFTLAAVSVDRYLAVRHPLRSRALRTPRNARAAVGLVWLLAALFSAPYLSYYGTVRYGALELCVPAWEDARRRALDVATFAAGYLLPVAVVSLAYGRTLRFLWAAVGPAGAAAAEARRRATGRAGRAMLAVAALYALCWGPHHALILCFWYGRFAFSPATYACRLASHCLAYANSCLNPLVYALASRHFRARFRRLWPCG-RRRR---HRARRALRRVRPASSGPPGCPGDARPSGRLLAGGGQGPEPREG-PVHGGEAARGPE--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F7V7-1", "uniprot_id": "GAL2B_DANRE", "id": "E7F7V7-1", "name": "Galanin receptor 2b", "aln": "MSDHEDLNKAMGHWNASESYQLNPASVIVSVVFSLIFLLGTIGNSLVLAVLLRSGQVGYN----TTNLFILNLSVADFFFIIFCVPFQATIYSLEGWVFGSFMCKVVHFFINLTMYASSFTLAAVSVDRYLAIRYPLRSRELRTPCNAVVAMVVIWGLSLVFAGPYLSYYDLIDFENSNVCVPGWEEHNRKVLDTCTFVFGYVIPVLIVSLSYTRTIKYLWTAVDPLDGMSESKR--AKRKVTKMIIIVTVLFCICWLPYHVVILCYLYGDFPFNQTTYAFRLLSHCMAYANSCLNPIVYALVSKHFRKGFKKVFSCILSKKGRNKVHVVNVANTVPGFEAGSTEVSQMNEENARQNESEMVNRPLAQPQDTTMTITLPFQNQP", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:* :::. . .:* *.*:*:****** :**.*******:.* .:: **:******:***: **: ******:**:*:.*:**:::**.**::* **************:*****:*:***** **** ** .*: ::* *: :*:.******. : : ::***.**: .*:.**..**. **::** :***:* **: :**:**.* .. : . * *. :. : :: *:.*:.:** *:*.:***: ** *.*. :*** ** ***:*********:**:*.*:*** *::::.* :: : .. . * .:*.. . . . . . : : ", "identical_positions": 161, "similar_positions": 114, "identity": "41.93%" }, { "cls_id": "homologset.agr.MGI:1329004", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A096MK60-1", "uniprot_id": "A0A096MK60_RAT", "id": "A0A096MK60-1", "name": "", "aln": "MPLRSEKKNNNKKKPSSFLKLAKVSILDSGTPSLTPGGKRAAEDRRRKRFQSKAEKMNFLTNLELNFAECILDGGRATMGVRQRVEMDATQRMRQNETISQAVCALLNSGGGVIRVEIENRDYNFERDGVGLDLPPLFRNHLDQMMHGRFFLIYVSSWTVEASGVRLATLCSNLYRRCGNFTEVMDPPEALTFLRN-VQVVRGLGDSDFLSLQEAP----VDDAQMVLASDVFNSQQLQYLEKLNFTESLHVEFQMFSADLAQGIRERLPKCVSALANSEGGYVFFGVH-ETGQVIGCEKEKLNCSNLLTTIDACIRRMPVYHFCAHNHKVQYTHRFLEVYDKKALHGYVCAIKVERFCCVAFAKAPDSWEVKDSVMKPLTAKDWTSWMTETNPELFSFPQMISRMNMLNTTPRSRTVFSHKYLKCVEDLQKDYFSVLPNRITYTPESVYKDLFSDYRGLRNLISAEMRCFSQGILIFSHSWAVDLGLQRERDVICDALLISPNNVPILYTICNKWDLRNRQYSMGVAYTLKQRLVNMGGYTGRLGIIPLVFPLGADQRVR--DDLEMPVYPESYNFITMEQVEALLQSLVIVLFGFRPLLNEELNSESETVALLTEQQHELLSMNLTKHRELFVHGLPGSGKTTLALMTLEKIKNVFNCQAEDILYICENQSLKKFV--SRKIVCQAVTRKAFMKNTYDNVQHIIVDEAQNFRTEEGNWYAKAKGIVQRGRDGPGVLYIFLDYFQINHLGCSGLPELQNQKPMLKLTRMLRSGDRIANYLQDIMHLIQNNPPPNVPRDALRMGEEPEGRANDTGSLEITNGLNLEQMANYVAEKCQGLWRTGYYPEDVAVLFTNVRDIEKCRERLLLAMRRRTMSQLGEESSLLVQVREGLDSPGNHIVLDSVQRFSGMERSIVFGIIPENFETDISYNVLLCLASRARTHLYIVRVRL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CBA2-1", "uniprot_id": "SLFN5_MOUSE", "id": "Q8CBA2-1", "name": "Schlafen family member 5", "aln": "--------------------------------------------------------MSFLEDLELNFAECIQDGGKATLGVRQREEMDTTHCMKQNEIISQAVCALLNSGGGVVRVEIENGDYNFERDGVGLNLPPLFRNHLDEMLYGKLFLIYVSSWDVAASHVRLATLCSNLYHRCGTFTEVMDPEKALKFLKR-VQDPRILGDSDSLNLQEAP----VDDAQMILASDLFHSPQLQYLEKLNFTKSSHVEFQMFSADLSQGIRERLPKCVSALANSEGGYVFFGVHDETRHVIGCEKEKINCTNLKSTIDACIRKMPVYHFCGQNHKVQYELKFLEVYDKEALHGYVCAIKVERFCCAAFAKAPDSWEIKDNNKKPLTANDWASRMIEINPDLSSFPQMIPWKSMLNTTPCSKTVFTHKYLKCVEDLQKDYFPVSPNRITYTPESVYKDLFADYRGLRNLINMEMRCFSQGILIFSHSWAVDLGLQRRQDVICDALLISPNNVPILYTICNKWDLGNRHYSMKVARTLKQKLVNMGGYPGRLGIIPLVLPLGSHQRVR--NDLEMPVYPESYNFITTQQVEALLQSLVIILFGFRPLLNEELNLESETVALLSDQQYGLLSTNLSKHREMFVHGLPGSGKTTLALMIVGKIRNVFNCQADNILYICENQSLKRFI--VRKNVCQAVTRKTFMKNTFDNVQHIIVDEAQNFRTEDGNWYAKAKAITQRARDGPGVLYIFLDYFQINHLCCSGLPELQHQKPLLKLTRMLRSGDNITSYLQDIMHQIRENPPPNVPQEALMVGEELEWGPDVTGNLEITDNLNLEQMSVYVAEKCQSLWRSGYF-TDVAVLFTRARDIEKCRDKLLLAMRRRSMSQLAEEPSLLVQVREGLDSLGSHVVLESVHRFSGMERSIVFGIIPMGSETAIFYNALLCLASRARTHLYIVKVVF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q08AF3-1", "uniprot_id": "SLFN5_HUMAN", "id": "Q08AF3-1", "name": "Schlafen family member 5", "aln": "--------------------------------------------------------MSLRIDVDTNFPECVVDAGKVTLGTQQRQEMDPRLREKQNEIILRAVCALLNSGGGIIKAEIENKGYNYERHGVGLDVPPIFRSHLDKMQKENHFLIFVKSWNTEAG-VPLATLCSNLYHRERTSTDVMDSQEALAFLKCRTQTPTNINVSNSLGPQAAQGSVQYEGNINVSAAALFDRKRLQYLEKLNLPESTHVEFVMFSTDVSHCVKDRLPKCVSAFANTEGGYVFFGVHDETCQVIGCEKEKIDLTSLRASIDGCIKKLPVHHFCTQRPEIKYVLNFLEVHDKGALRGYVCAIKVEKFCCAVFAKVPSSWQVKDNRVRQLPTREWTAWMMEADPDLSRCPEMVLQLSLSSATPRSKPVCIHKNSECLKEQQKRYFPVFSDRVVYTPESLYKELFSQHKGLRDLINTEMRPFSQGILIFSQSWAVDLGLQEKQGVICDALLISQNNTPILYTIFSKWDAGCKGYSMIVAYSLKQKLVNKGGYTGRLCITPLVCVLNSDRKAQSVYSSYLQIYPESYNFMTPQHMEALLQSLVIVLLGFKSFLSEELG--SEVLNLLTNKQYELLSKNLRKTRELFVHGLPGSGKTILALRIMEKIRNVFHCEPANILYICENQPLKKLVSFSKKNICQPVTRKTFMKNNFEHIQHIIIDDAQNFRTEDGDWYGKAKFITQTARDGPGVLWIFLDYFQTYHLSCSGLPPPSDQYPREEINRVVRNAGPIANYLQQVMQEARQNPPPNLPPGSLVMLYEPKWAQGVPGNLEIIEDLNLEEILIYVANKCRFLLRNGYSPKDIAVLFTKASEVEKYKDRLLTAMRKRKLSQLHEESDLLLQIGDASDVLTDHIVLDSVCRFSGLERNIVFGINPGVAPPAGAYNLLLCLASRAKRHLYILKASV", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.: ::: **.**: *.*:.*:*.:** ***. :*** * :***********:::.**** .**:**.****::**:**.***:* . ***:*.** . *. * *********:* . *:***. :** **: .* :. *: *. * * :. : *: :*. :********:.:* **** ***:*::: :::********:**:********** ** :********:: :.* ::**.**:::**:*** :. :::* .****:** **:*********:***..***.*.**::**. : *.:.:*:: * * :*:* *:*: .: .:** *:.* ** :*::: ** **.* .:*:.*****:**:**::::***:**. *** *********:*********..:.********* **.****** .*** : *** ** :***:*** ***.*** * *** *.:.::.: . : :*******:* :::*********:*:**:.:*.***. **.: **:::*: *** ** * **:*********** *** : **:***:*:. :********.**::: :* :**.****:****.::::****:*:*******:*:**.*** *.* .*******:******* ** ***** ..* * ::.*::*... *:.***::*: ::*****:* :* : * : . .*.*** :.****:: ***:**: * *.** *:*****.. ::** :::** ***:*.:*** **..**:*: :. * .*:**:** ****:**.***** * . ** ********: ****::. .", "identical_positions": 473, "similar_positions": 250, "identity": "49.79%" }, { "cls_id": "homologset.agr.MGI:1329005", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A1L1STQ7-1", "uniprot_id": "A0A1L1STQ7_MOUSE", "id": "A0A1L1STQ7-1", "name": "", "aln": "MPGASEMKDGPEQEQRHRAGHTWKHGIRASSWLAVGNSQEKSPSVDCRSSHRTLGFSRTGVCLHTAILPTEDNGLNLWKQKGLHLGNRGSDWKTNIIVDQDTDYAELVLFIGEITLGEKNRNSMKDIQLRRKEAKSILQAVCTLLNSGGGVVKAHIKNQNYSFTRDGMGLDLVNSLPGIMHLPHDYLDFMQHKDYFFVFVKPLKPNQKGPGITTLKTNLYRRINSISDEVKVANAVQLLKSRTDPEEKAESRPSSPGKIVCNETLN----ECLS--LFNRDWLAYEETFCFTKSIHAEVKLTPKEKIFPKEKILELLPQTVSAFANTDGGFLFIGLDGKTQQIIGFEAEKSNLVLLESEIEKCIQQLPVTHFCGEKEKIKYTCKFIEVRKSGAVCAYVCALRVERFCCAVFAAEPESWHVEGGCVKRFTTEEWVKRQMDATA-----------------------------------------VMPGKVICCPEALYMKPFSQHEGYEHLVRTELGSLLKGTLVISKSWALDLGLQEKQEVIWDVLHISQGSLLTLYVFVQGDENLEGNSSLLGELGAELKGYYKQIALTLKQMLLNHCGYTAEIGIIVKITYLGH--KTMCLYDTSTKIRYPQKYYLSA--KAVKDLEKALVEILGSYESFYSLPRRNWDSFMSAFLNVGSYIVPVLRNV-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K4S0-1", "uniprot_id": "A0A0G2K4S0_RAT", "id": "A0A0G2K4S0-1", "name": "", "aln": "-----------------------MAGNLPRLVEDVNPQTFTEPSVQLKCPGNIFQGGR-----HAKPGSWKDS------QKGFHLGSRDSNCKMSITVDQDTDYAELVLSIGEITLGEKTRKSMKDSQRRKREAKTFQQAVCTLLNSGGGVAKARIKNQNYDFSRDGVGQDLENFLPHILDFPHEYLDFKQVKDYFLMFVKAWKLKQKGPGITTLKTNLYIRSISSSIELKAVNAVKFLKS----------RLSSPGTIVCNEVLN----ECLN--LFNRDCFTCKEKFCFTKATHAEVKLTPKE------NILEILPQTVSSFANADGGYLFIGLDGKTQEIIGFEAEKSDLVHLESEIEKCIRQLPVTHFCEEREKIKYTCKFMEVHKPGAACSFVCALRVERFCCAVFAAEPESWHVEDSCVKRFTAEDWVKRQMDGPA-----------------------------------------LISGKVISSPEALCGKLFSTQEAHEQLLWAQLDSLPKGTLVVTKRWALDLPLQDKHGVILDTLHIPQDSLLTLHGFVLGGEDLEDDSTLLRELGAELKGYYKQTAVTLKQTLANHGSYTEKIGIAIKITYLGHN-KAVSLYDSSSKIHYPTKYYLTT--ETAKNLEKALAEILGS----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8IYM2-1", "uniprot_id": "SLN12_HUMAN", "id": "Q8IYM2-1", "name": "Ribonuclease SLFN12", "aln": "---------------------------------------------------------------------------------------------MNISVDLETNYAELVLDVGRVTLGENSRKKMKDCKLRKKQNESVSRAMCALLNSGGGVIKAEIENEDYSYTKDGIGLDLENSFSNILLFVPEYLDFMQNGNYFLIFVKSWSLNTSGLRITTLSSNLYKRDITSAKVMNATAALEFLKDMKKTRGRLYLRPELLAKRPCVDIQEENNMKALAGVFFDRTELDRKEKLTFTESTHVEIKNFSTEKLLQ--RIKEILPQYVSAFANTDGGYLFIGLN-EDKEIIGFKAEMSDLDDLEREIEKSIRKMPVHHFCMEKKKINYSCKFLGVYDKGSLCGYVCALRVERFCCAVFAKEPDSWHVKDNRVMQLTRKEWIQFMVEAEPKFSSSYEEVISQINTSLPAPHSWPLLEWQ-----RQRHHCPGLSGRITYTPENLCRKLFLQHEGLKQLICEEMDSVRKGSLIFSRSWSVDLGLQENHKVLCDALLISQDSPPVLYTFHMVQD-------------EEFKGYSTQTALTLKQKLAKIGGYTKKVCVMTKIFYLSPEGMTSCQYDLRSQVIYPESYYFTRRKYLLKALFKALKRLKSLRDQFSFAENLYQIIGIDCFQKNDKKMFKSCRRLT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6IEE8-1", "uniprot_id": "SN12L_HUMAN", "id": "Q6IEE8-1", "name": "Schlafen family member 12-like", "aln": "-----------------------------------------------------MDLAR----------------------KEFLRGNGLAAGKMNISIDLDTNYAELVLNVGRVTLGENNRKKMKDCQLRKQQNENVSRAVCALLNSGGGVIKAEVENKGYSYKKDGIGLDLENSFSNMLPFVPNFLDFMQNGNYFHIFVKSWSLETSGPQIATLSSSLYKRDVTSAKVMNASAALEFLKDMEKTGGRAYLRPEFPAKRACVDVQEESNMEALAADFFNRTELGYKEKLTFTESTHVEIKNFSTEKLLQ--RITEILPQYVSAFANTDGGYLFVGLN-EDKEVIGFKAEKSYLTKLEEVTKNSIGKLPVHHFCVEKGTINYLCKFLGVYDKGRLCGYVYALRVERFCCAVFAKKPDSWHVKDNRVKQLTEKEWIQFMVDSEP----VCEELPSPASTSSPVSQSYPLREYINFKIQPLRYHLPGLSEKITCAPKTFCRNLFSQHEGLKQLICEEMGSVNKGSLIFSRSWSLDLGLQENHKVLCDALLISQDKPPVLYTFHMVQD-------------EEFKDYSTQTAQTLKQKLAKIGGYTKKVCVMTKIFYLSPEGKTSCQYDLNSQVIYPESYYWTT-AQTMKDLEKALSNILPKENQIFLFVCLFRFCLFVCWF--------VCFFLR", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* :* :*:****** :*.:****:.*:.*** : *::: :.. :*:*:******** **.::*:.*.:.:**:* ** * :. :: : ::*** * :** :***. . : .* *:**.:.** * : : ::. *:::**. * . .. * : : :.* :*:* : :*.: **:: *.*:* ..* .* *:*** **:***:***:**:**: : :::***:** * * ** ::.* ::** *** *: .*:* ***: * . * *.:* ************* :*:****:.. * ::* ::*:: ::. . :. :: *: : : * :*. ::*: ::.*: **:*:.:: *::** **::: *: *.* *.*.. .*: * : *:*.* .* * **** * : .** :: : ** **. : . ** ::: ** .** : * * *** .: ", "identical_positions": 180, "similar_positions": 167, "identity": "26.01%" }, { "cls_id": "homologset.agr.MGI:1329012", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VCA2-1", "uniprot_id": "ORCT_DROME", "id": "Q9VCA2-1", "name": "Organic cation transporter protein", "aln": "-----------------------------------MGYDDVITHLGEFGPYQKRIYYLLCLPAIVCAFHKLAGVFLLAKPDFRCALPYENGSIYELSPHLWNLSYP----------ENERCSYYDVD------YTEEYLN------GSIPRSSNETKTCSS-YVYDRSKYLNSAVTEWNLVC-SRSLLSATSDSLFMLGVLLGSLIFGQMSDKLGRKPTFFASLVLQLIFGVLAAVAPEYFSYTISRMIVGATTSGVFLVAYVIALEMVGSSY-RLFAGVAMQMFF-------SVGFMLTAGFAYFIHDWRWLQIAITLPGLLFLCYYWIIPESARWLLMKGRKDEAFVIIEKAAKENKVEVPNEIYEQLVD------EVAEKKKQDEMAASQPA-----------ATVFDLLRYPNLRRKTLLIFFDWFVNSGVYYGLSWNTNNLGGNQ----------------LVNFMISGAVEIPGYTLLLFTLNRWGRRSILCGTMMVAGISLLATIFVPSDM-------------------NWLIVACAMIGKLAITSSYGTIYIFSAEQFPTVVRNVGLGASSMVARVGGILAPYLK------------LLGEIWRPLPLIICGALSLTAGLLSLLLPETLNKPMPETIEDGENFGKKPAPQETAEEG------------GTQELSG--MLNGKSG", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q95R48-1", "uniprot_id": "OCTL_DROME", "id": "Q95R48-1", "name": "Organic cation transporter-like protein", "aln": "-----------------------------------MGYDEAIIHLGDFGRYQKIIYFLICLTSIPVAFHKLAGVFLLAKPDFRCALPFENGSSYDLPTHLWNLSYP----------ENERCSYYDVD------YTEEYLN------GSIPRSSNETKTCSS-YVYDRSKYLNSAVTEWNLVC-GRDFMAATSDSLFMLGVLLGSIVFGQLSDKYGRKPILFASLVIQVLFGVLAGVAPEYFTYTFARLMVGATTSGVFLVAYVVAMEMVGPDK-RLYAGIFVMMFF-------SVGFMLTAVFAYFVHDWRWLQIALTLPGLIFMFYYWIIPESARWLLLKGRKDCAIANMQKAARFNKVEISDEALSELLDEGENSEEKAKQKLEDQELDEGPP-----------PSVWDLFCYPNLRRKTLLIFLDWLVTSGVYYGLSWNTSNLGGNV----------------LLNFVISGAVEIPAYIFLLLTLNRWGRRSILCGCLVMAGLSLLATVIIPQRM-------------------HTLIVACAMLGKLAITASYGTVYIFSAEQFPTVVRNVALGAASMVARISGMMAPFLN------------FLATIWKPLPLLICGSLTLVAGLLSLLLPETHNKPMLETIADGERFGKKTKADVYLETGQELRAPEAQPLKGSGETNGSTIANGHK-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "O70594-1", "uniprot_id": "S22A5_RAT", "id": "O70594-1", "name": "Organic cation/carnitine transporter 2", "aln": "----------------------------------MRDYDEVTAFLGEWGPFQRLIFFLLSASIIPNGFNGMSIVFLAGTPEHRCLVPHTVNLSSAWRNHSIPLETK------DGRQVPQSCRRYRLA------TIANFSALGLEPGRDVDLEQLEQENCLDGWEYNKDVFLSTIVTEWDLVC-KDDWKAPLTTSLFFVGVLMGSFISGQLSDRFGRKNVLFLTMGMQTGFSFLQLFSVNFEMFTVLFVLVGMGQISNYVAAFVLGTEILSKSIRIIFATLGVCIFY-------AFGFMVLPLFAYFIRDWRMLLLALTVPGVLCGALWWFIPESPRWLISQGRVKEAEVIIRKAAKFNGIVAPSTIFD-------------PSELQDLNSKKPQS-----------HHIYDLVRTRNIRIITIMSIILWLTISVGYFGLSLDTPNLHGDI----------------YVNCFLLAAVEVPAYVLAWLLLQHLPRRYSISAALFLGGSVLLFIQLVPSEL-------------------FYLSTALVMVGKFGITSAYSMVYVYTAELYPTVVRNMGVGVSSTASRLGSILSPYFV------------YLGAYDRFLPYILMGSLTILTAILTLFFPESFGAPLPDTIDQMLRVKGIKQWQIQSQTRT-----------QKDGGESPTVLKSTAF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z0E8-1", "uniprot_id": "S22A5_MOUSE", "id": "Q9Z0E8-1", "name": "Organic cation/carnitine transporter 2", "aln": "----------------------------------MRDYDEVTAFLGEWGPFQRLIFFLLSASIIPNGFNGMSIVFLAGTPEHRCLVPHTVNLSSAWRNHSIPLETK------DGRQVPQKCRRYRLA------TIANFSELGLEPGRDVDLEQLEQESCLDGWEYDKDVFLSTIVTEWDLVC-KDDWKAPLTTSLFFVGVLMGSFISGQLSDRFGRKNVLFLTMGMQTGFSFLQVFSVNFEMFTVLFVLVGMGQISNYVAAFVLGTEILSKSIRIIFATLGVCIFY-------AFGFMVLPLFAYFIRDWRMLLLALTVPGVLCGALWWFIPESPRWLISQGRIKEAEVIIRKAAKINGIVAPSTIFD-------------PSELQDLNSTKPQL-----------HHIYDLIRTRNIRVITIMSIILWLTISVGYFGLSLDTPNLHGDI----------------YVNCFLLAAVEVPAYVLAWLLLQYLPRRYSISAALFLGGSVLLFMQLVPSEL-------------------FYLSTALVMVGKFGITSAYSMVYVYTAELYPTVVRNMGVGVSSTASRLGSILSPYFV------------YLGAYDRFLPYILMGSLTILTAILTLFFPESFGVPLPDTIDQMLRVKGIKQWQIQSQTRM-----------QKDGEESPTVLKSTAF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O76082-1", "uniprot_id": "S22A5_HUMAN", "id": "O76082-1", "name": "Organic cation/carnitine transporter 2", "aln": "----------------------------------MRDYDEVTAFLGEWGPFQRLIFFLLSASIIPNGFTGLSSVFLIATPEHRCRVPDAANLSSAWRNHTVPLRLR------DGREVPHSCRRYRLA------TIANFSALGLEPGRDVDLGQLEQESCLDGWEFSQDVYLSTIVTEWNLVC-EDDWKAPLTISLFFVGVLLGSFISGQLSDRFGRKNVLFVTMGMQTGFSFLQIFSKNFEMFVVLFVLVGMGQISNYVAAFVLGTEILGKSVRIIFSTLGVCIFY-------AFGYMVLPLFAYFIRDWRMLLVALTMPGVLCVALWWFIPESPRWLISQGRFEEAEVIIRKAAKANGIVVPSTIFD-------------PSELQDLSSKKQQS-----------HNILDLLRTWNIRMVTIMSIMLWMTISVGYFGLSLDTPNLHGDI----------------FVNCFLSAMVEVPAYVLAWLLLQYLPRRYSMATALFLGGSVLLFMQLVPPDL-------------------YYLATVLVMVGKFGVTAAFSMVYVYTAELYPTVVRNMGVGVSSTASRLGSILSPYFV------------YLGAYDRFLPYILMGSLTILTAILTLFLPESFGTPLPDTIDQMLRVKGMKHRKTPSHTRM-----------LKDGQERPTILKSTAF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PJE3-1", "uniprot_id": "A0A8M9PJE3_DANRE", "id": "A0A8M9PJE3-1", "name": "", "aln": "----------------------------------MGNYDEDTAFLGQTGPFFIRLFCLLNLIYISTGLHGLYIVFVAASPAHRCRV--DVNLTEDWLEASAPTETLS-----NGDLQVSQCWRYSLQ------TLTNLSGQGYSPGQ-INITDIPRERCEDGWVYSADVYHSTIVSEWDLVC-DSEWRVPLASSTLYMGYLLGSIVSGQLSDRFGRKKVLFGSLAAEALLMFAQSFSPSWLIFCVLYFFIGAFQISLYITAFVLGNEVLSGSLRVLFTTLGAFLHY-------CVGYMLLPWVAFAIRHWRTLLRVLSGLTVVYIPLWWLIPESPRWLLSQGHVQESEAILRDAARKNRVPAPEVIFK-------------QSQIKEAAFQKSK------------YSALDVLRTSNIRRTTFMCLLLWMAINIGYFGLSLNTTNLSGDP----------------FLNCFLSAVTEVPAYIVSTFLLKSCPRRPVLSAFLVIGGGFLLLVQLIPDRL-------------------QTLALALEMAGKFGFTMSFTVVYIYTAELYPTVLRNLGMGMCSSAARIGSITAPYII------------FLGTFNRHLPYVLMGSLTITASLANLFLPETFGKVLPENLEQMQKSRSFPGRDKQSVE---------------DGGGGEKMREEKL-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VNX2-1", "uniprot_id": "Q9VNX2_DROME", "id": "Q9VNX2-1", "name": "", "aln": "-----------MAASEAPPADPAVEVAPPAKDSEDVTLDAILKHLGQFGRFQLIIFLLICLPMMFHAMFSVTYVFTAATVTHRCSVEECD-LPGSNYYEPHTNWSIP-----KNGKDLDSCNRYTN------SELPQWN-HSVDICSADHFTKNKEACAHNEFVFRDD--EVTISNDFGIFC-DDEWKLSMVGTINNLGQFFGIPIGGFVADRYGRSFSIALGGILGAVLGVIRSFSPSYGWFLVFEFLDNMTSSTLYSTCFVIGIELVGPKR-RVLACSVITVFY-------AVGEVLLAMSAKAFHDWRILLRITYGPSLILLAYFWILPESVRWLLSQGKEERAKNILRRAAHVNKRELPESVLDKLVL--------ANRDKLQ-QSSESR------------FPIREAFKNFKWR--IANCSLCWIVHVLVYYGLSLNVVLLDGDK----------------YNNFAYIALVEIPGFFMPLLIMDRFGRRYSLCGLMLASGLCCIGTIFTGADQ-------------------PVLQLVLFLVGKLTITASFQVLYFFASEIYPTNLRNSLLSFCSMMGRFGSMLAPQTP------------LLAKYYANAPAMLFAGAAIVSGLLTLFFPETTNVVLPTTVQEADAIGVKKQSKSKDLDLV--------------------VTATQAQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VNW8-1", "uniprot_id": "Q9VNW8_DROME", "id": "Q9VNW8-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "MTSQKEGNGYRRSDSKTTGHADAEAATQTAGGDEDNSLDAILVRIGQFGRYQIINYVLLCVPMLFNAFFSISYVFTASTVVHRCTVPQCD-SPSSVYEEDWLGFTIP-----KKNSAWDDCHRYAAN---ISDAISGYTDPSGQYCLKEYFTITSETCGR-DFKFRDE--EKTISTEFGIYC-EDEWKLSMVGTINNVGQFVGIPLGGYFADRYGRRTMLAVAGSVSALMGVIRSLSSNYSMFLVFEFLDMAVGSTLFPTAFLLAIELVGPKR-RVAAATIITIFY-------ALGEAFLGFLASQVQHWRWLLRVLYAPAVLQILFLWILPESVRWLLSQGAEEKASNVLRRAARINQRPLPEEQLNDLLT--------SNRQKLS-QANESQ------------YPIMRAVVFFSLR--IANCCLCWFTHTLIALGLSLNSVNLGGNK----------------YTNFMLNGFIQIPGLLLPLVIMDRVGRRHSLCASMLLCAICMGASAAVPADN-------------------YAGSLALFLIGKLAITCSFQILYFFTSEIFPTNVRNTLLSLCSMVGRIGSMLAPQTP------------LLAKYYIYAPQILFATFALISGFLTLAFPETADKVLPTTIEEARDLNQAKRRSERSP------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A0B4KFK6-1", "uniprot_id": "A0A0B4KFK6_DROME", "id": "A0A0B4KFK6-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "-----------------------MSAPAAGAASAVLDFDDILVEIGEFGRFQRRNYLLICLPVLFAAANSLSYVFTAGSPTYRCYVPECDKLVDAEYGANWVSIAVPGSWSKRGHFTPSTCERFVANGDHLESSSDPWSAWPLDQCFAENFTTETERCNQ--FVYGSS--ERTIVQQWGLQCPENLWKLAFVGTIHFAGLVVGTALSGYLADRYGRKHIFLFCIVFMALTGVAQALSWDYISFLFFALLNAVGTSGVYPLAFIIGVEMVGPRK-REMSSIVLNYFY-------AVGEALLGLSV-FLPDWRQLQLALSVPPLICVAYFWLVPESVRWLLARNRREQAGVIIRRAAKVNRRDISVELMASFKQ--------QELDAETGQEDDVEGGLHVKKDDKIWLAVKEVARSHILMGRYAILLLIWAVNAIVYYGLSLNATSLSGNK----------------YLNFALVCLVEIPGYSLAWLFLRRFGRRVALSGSLLLCSITCVASGFVTLAQGDWIPCQTGVESRHSWSCANWLVVTLFLVGKLGITSSFAVIYTFTAEMMPTVIRSGGVGVMSTFARFGAMLAPFVP------------LLASYYDPLPLLLFGTLSLVAGLLSLLLPETFNRKLPDTVEEAIALGK---------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P25297-1", "uniprot_id": "PHO84_YEAST", "id": "P25297-1", "name": "Inorganic phosphate transporter PHO84", "aln": "----------------------------------MSSVNKDTIHVAERSLHKEH----LTEGGNMAFHNHLNDFAHIEDPLERRRLALESIDDEGFGWQQVKTISIAG-----VGFLTDSYDIFAIN---------------LGITMMSYVYWHGSMPGPSQTLLKVSTSVGTVIGQFGFGTLADIVGRKRIYGMELIIMIVCTILQTTVAHSPAIN---FVAVLTFYRIVMGIGIGGDYPLSSIITSEFATTKWRGAIMGAVFANQAWGQISGGIIALILVAAYKGELEYANSGAECDARCQKACDQMWRILIGLGTVLGLACLYFRLTIPESPRYQLDVNAKLELAAAAQEQDGEKKIHDTSDEDMAING-----LERASTAVESLDNHPPKAS---------FKDFCRHFGQWKYGKILLGTAGSWFTLDVAFYGLSLNSAVILQTIGYAGSKNVYKKLYDTAVGNLILICAGSLPGYWVSVFTVDIIGRKPIQLAGFIILTALFCVIGFAYHKLG-----------------DHGLLALYVICQFFQNFGPNTTTFIVPGECFPTRYRSTAHGISAASGKVGAIIAQTALGTLIDHNCARDGKPTNCWLPHVMEIFALFMLLGIFTTLLIPETKRKTLEEINELYHDEIDPATLNFRNKNND-------------IESSSPSQLQHEA-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :.: . . : : . * : : . : ::.: .. : .:. . . .. .: . :.. : . : . . . ** * : :*** *: : . . : . * . *** : : * .:*. . . : *: :. : : . : ..* ** *. . : .:...: : : . : : .* :**: : ", "identical_positions": 22, "similar_positions": 83, "identity": "3.17%" }, { "cls_id": "homologset.agr.MGI:1329013", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q61390-1", "uniprot_id": "TCPW_MOUSE", "id": "Q61390-1", "name": "Probable T-complex protein 1 subunit zeta-2", "aln": "MAAIKIANPGAEVTRSQAALAVNICAARGLQDVLRPTLGPKGALKMLVSGAGDIKLTKDGNVLLHEMQIQHPTASIIAKVAAAQDHVTGDGTTSNVLIIGELLKQADLYISEGLHPRIITEGFDVAKTKALEVLDEIKVQKEMK---REILLDVARTSLQTKVHAELADILTEAVVDSVLAIRRPG--VPIDLFMVEIVEMRHKSETDTQLIRGLVLDHGARHPRMRKQVRDAYILTCNVSLEYEKTEVSSGFFYKTVEEKEKLVKAERKFIEDRVQKIIDLKQKVCAE-SNKGFVVINQKGIDPVSLEMLAKHNIVALRRAKRRNLERLTLACGGLAVNSFEGLSEECLGHAGLVFEYALGEEKFTFIEDCVNPLSVTLLVKGPNKHTLIQIKDALRDGLRAVKNAIEDGCVVPGAGAVEVAIAEALVNY---KHRVQGRVRLGIQAFADALLIIPKVLAQNSGYDLQETLIKIQTKHAESKE-----LLGIDLNTGEPMAAAEAGIWDNYCVKKHLLHSCTVIATNILLVDEIMRAGMSSLRD---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92526-1", "uniprot_id": "TCPW_HUMAN", "id": "Q92526-1", "name": "Probable T-complex protein 1 subunit zeta-2", "aln": "MAAIKAVNSKAEVARARAALAVNICAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDGNVLLDEMQIQHPTASLIAKVATAQDDVTGDGTTSNVLIIGELLKQADLYISEGLHPRIIAEGFEAAKIKALEVLEEVKVTKEMK---RKILLDVARTSLQTKVHAELADVLTEVVVDSVLAVRRPG--YPIDLFMVEIMEMKHKLGTDTKLIQGLVLDHGARHPDMKKRVEDAFILICNVSLEYEKTEVNSGFFYKTAEEKEKLVKAERKFIEDRVQKIIDLKDKVCAQ-SNKGFVVINQKGIDPFSLDSLAKHGIVALRRAKRRNMERLSLACGGMAVNSFEDLTVDCLGHAGLVYEYTLGEEKFTFIEECVNPCSVTLLVKGPNKHTLTQVKDAIRDGLRAIKNAIEDGCMVPGAGAIEVAMAEALVTY---KNSIKGRARLGVQAFADALLIIPKVLAQNAGYDPQETLVKVQAEHVESKQ-----LVGVDLNTGEPMVAADAGVWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMSSLK----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VXQ5-1", "uniprot_id": "Q9VXQ5_DROME", "id": "Q9VXQ5-1", "name": "", "aln": "MASISLLNPKAEFARAAQALAINISAAKGLQDVMRTNLGPKGTVKMLVSGAGDIKITKDGNVLLHEMQIQHPTASMIARASTAQDDSTGDGTTTTVMLIGELLKQADIYLSEGLHPRIMTDGFEKARDKALEVLDQVKVPVEIN---KKNLVEVANTSLKTKVHPALADLLTDVCVNAVLTIASADKTKPVDLHMVELMEMQHKSDTDTQLVRGLVMDHGARHPDMPKRLENAYILTANVSLEYEKAEVNSGFFYKTAEEREAFVRAEREFIDQRVKKVIELKRSVCDG-TDKTFVLINQKGIDPISLDALAKEGILALRRAKRRNMERLSLACGGTAMNSFDDLQEEHLGYAGVVYEHVLGENKYTFVEDCKNPLSVTILIKGPNKHTITQIKDAIRDGLRAINNTIADKALVPGAGAFEVRAYNELVAF---KDTIKGKSRLAVQAFADALLVIPKTLAVNSGYDAQDTIVKLTVEDRLSPE-----LVGLDLATGEPMKPVDLGVYDNYIVKKQILNSCSIIASNLLLVDEVMRAGMTSLKG---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39079-1", "uniprot_id": "TCPZ_YEAST", "id": "P39079-1", "name": "T-complex protein 1 subunit zeta", "aln": "-MSLQLLNPKAESLRRDAALKVNVTSAEGLQSVLETNLGPKGTLKMLVDGAGNIKLTKDGKVLLTEMQIQSPTAVLIARAAAAQDEITGDGTTTVVCLVGELLRQAHRFIQEGVHPRIITDGFEIARKESMKFLDEFKISKTNLSNDREFLLQVARSSLLTKVDADLTEVLTPIVTDAVLSVYDAQ-ADNLDLHMVEIMQMQHLSPKDTTFIKGLVLDHGGRHPDMPTRVKNAYVLILNVSLEYEKTEVNSGFFYSSADQRDKLAASERKFVDAKLKKIIDLKNEVCGMDPDKGFVIINQKGIDPMSLDVFAKHNILALRRAKRRNMERLQLVTGGEAQNSVEDLSPQILGFSGLVYQETIGEEKFTYVTENTDPKSCTILIKGSTHYALAQTKDAVRDGLRAVANVLKDKNIIPGAGAFYIALSRYLRSANMNKLGAKGKTKTGIEAFAEALLVIPKTLVKNSGFDPLDVLAMVEDELDDAQDSDETRYVGVDLNIGDSCDPTIEGIWDSYRVLRNAITGATGIASNLLLCDELLRAGRSTLKETPQ", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::. *. ** * ** :*: :*.***.*:...*****::****.***:**:****:*** ***** *** :**:.::***. ******: * ::****:**. ::.**:****:::**: *: ::::.*::.*: :: *::**.:** ***.. *:::** .::**:: . :**.***:::*:* .** :::***:***.*** * .::.:*::* ********:**.*****.:.:::: :. :**:*:: :::*:*:** .** .:* **:********.**: :**..*:*********:*** *. ** * **.:.* : **.:*:*:: .:**:*:*:: : :* * *:*:**..:::: * ***:******: *.: * ::*****. : . * * :*: : .::***:***:***.*. *:*:* :.: : : : : :*:** *:. .. *::*.* * :: : ..: **:*:** **::*** ::*: ", "identical_positions": 229, "similar_positions": 191, "identity": "41.79%" }, { "cls_id": "homologset.agr.MGI:1329014", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P70297-1", "uniprot_id": "STAM1_MOUSE", "id": "P70297-1", "name": "Signal transducing adapter molecule 1", "aln": "MPLFATN-PFDQDVEKATSELNTAEDWGLILDICDKVGQSR-TGPKDCLRSIMRRVNHKDPHVAMQALTLLGACVSNCGKIFHLEVCSRDFASEVSNVLNKGHPKVCEK--LKALMVEWTD-EFKNDPQLSLISAMIKNLKEQGVTFPAIGSQAAEQAKASPALVAKDPGTVATKKEEEDLAKAIELSLKEQRQQ-----------SAPVSTLYPSTS---------NLLTNHQHEGRKVRAVYDFEAAEDNELTFKAGEIITVLDDSDPNWWKGETHQGVGLFPSNFVTADLTAEPEMIKTEKKTVQFNDDVQ------------IETIEPEPEP--AFIDEDKMDQLLQMLQSTDPSDNQPDLPELLHLEAMCHQMGPLIDEKLEDIDRKHSELSELNVKVMEALSLYTKLMNEDPMYSMYAKLQSQQYYLQSSAVSASQVYPGP--AQSGTYLVAGSAQMTHLQSYS---LPPEQLSSISQGAVP-----SSANQALPSQQTQASYPNAMVSSVQG--NSYPSQASIYSPPAAAAAAAAAAVVPVP------------------------------VPADVTIYQNA----------GPTMSQVPN-------------------YTLTSSTLPQTGGSQQPP---QPQQAYSQKALL-------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B5DF55-1", "uniprot_id": "B5DF55_RAT", "id": "B5DF55-1", "name": "", "aln": "MPLFATN-PFDQDVEKATSELNTAEDWGLILDICDKVGQSR-TGPKDCLRSIMRRVNHKDPHVAMQALTLLGACVSNCGKIFHLEVCSRDFASEVSNVLNKGHPKVCEK--LKALMVEWTD-EFKNDPQLSLISAMIKNLKEQGVTFPAIGSQAAEQAKASPALVAKDPGTVATKKEEEDLAKAIELSLKEQRQQ-----------AAPLSTLYPSTS---------SLLTNHQHEGRKVRAVYDFEAAEDNELTFKAGEVITVLDDSDPNWWKGETHQGMGLFPSNFVTADLTAEPEMIKTEKKTVQFSDDVQ------------IETIEPEPEPEPAFIDEDKMDQLLQMLQSTDPSDNQPDLPELLHLEAMCHQMGPLIDEKLEDIDRKHSELSELNVKVMEALSLYTKLMNEDPVYSVYAKSQSQQYYVQASGVSAPQVYPGP--AQSGAYLVAGNAQMTHLQSYS---LPPEQLASISQGAVP-----PSATPALPNQQAQASYPNAMVSSVQG--NSYPSQASIYSP---AAAAAAVAVTAVP------------------------------VPADVTIYQNP----------GPNMSQVPN-------------------YTLTSSTLPHTGGSQQPP---QPQQAYSQKALL-------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q92783-1", "uniprot_id": "STAM1_HUMAN", "id": "Q92783-1", "name": "Signal transducing adapter molecule 1", "aln": "MPLFATN-PFDQDVEKATSEMNTAEDWGLILDICDKVGQSR-TGPKDCLRSIMRRVNHKDPHVAMQALTLLGACVSNCGKIFHLEVCSRDFASEVSNVLNKGHPKVCEK--LKALMVEWTD-EFKNDPQLSLISAMIKNLKEQGVTFPAIGSQAAEQAKASPALVAKDPGTVANKKEEEDLAKAIELSLKEQRQQ-----------STTLSTLYPSTS---------SLLTNHQHEGRKVRAIYDFEAAEDNELTFKAGEIITVLDDSDPNWWKGETHQGIGLFPSNFVTADLTAEPEMIKTEKKTVQFSDDVQ------------VETIEPEPEP--AFIDEDKMDQLLQMLQSTDPSDDQPDLPELLHLEAMCHQMGPLIDEKLEDIDRKHSELSELNVKVMEALSLYTKLMNEDPMYSMYAKLQNQPYYMQSSGVSGSQVYAGP--PPSGAYLVAGNAQMSHLQSYS---LPPEQLSSLSQAVVP-----PSANPALPSQQTQAAYPNTMVSSVQG--NTYPSQAPVYSP---PPAATAAAAT-----------------------------------ADVTLYQNA----------GPNMPQVPN-------------------YNLTSSTLPQPGGSQQPP---QPQQPYSQKALL-------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9XTL2-1", "uniprot_id": "Q9XTL2_DROME", "id": "Q9XTL2-1", "name": "", "aln": "MGIFGQSSPFDADVEKATSETNTNDNWSLILDVCDKVTTNP-RLAKDCLKAVMRRMGHTDPHVVMQAITLLDALSNNCGKPLHLEVASRDFETEFRRLLAKAQPKVSLK--MRQVLKNWAENDYKNDRELDLIPALYAKLRQEGYDFKNLGDKTSKTVAEKAAALPKDPNVVSSQQEEDDIAKAIELSLKENKGSPKTGSVASTGTASAYPSLYPSFAGTGSSAPSAEASSAPAPEPRKVRALYDFEAAEENELTFFAGEIIHVLDDSDPNWWKGYNQRGEGLFPSNFVTADLSVDPERLDINQQHKSAAAAGQRELDSAAALQQKTEAAAAAAAAQPVEIDESKIDRLLHLLHEANPEDPSQDSDEMLQLEQEVHQMGPLIDAELERVDRKHAQLTQLSSDLVDAINLYHTLMRDDRAAAGHFAAAAGGFMPGLAGFPGAALYGAPGYPAAGGFPPAQNYPGMHSMPYGPVPNPPTSAPSQAPGAPGGYLGQPQGQVPLPYQNGHAAQMNSLPAHLTQPTGTAPMPQPIYTQPTPVTTQQQQQPLPQHPQQPPQQQGQQPPQHPQNSYHIDPQSQYAQVPPAVTQIQQPQQPPAPHAYMSPQHQQAPPPQGYQPGPNLYGPNGSPAVVNPQSYMSPQQQQQQHPPPHDQFSQLHQQMAAMSMAGGPPVGAPGYHMQNDAVKNNIPIYQQQR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38753-1", "uniprot_id": "HSE1_YEAST", "id": "P38753-1", "name": "Class E vacuolar protein-sorting machinery protein HSE1", "aln": "--MSSSAIKIRNALLKATDPKLRSDNWQYILDVCDLVKEDPEDNGQEVMSLIEKRLEQQDANVILRTLSLTVSLAENCGSRLRQEISSKNFTSLLYALIESHSVHITLKKAVTDVVKQLSD-SFKDDPSLRAMGDLYDKIKRKAPYLVQPNVPEKHNMSTQADNSDDEELQKALKMSLFEYEKQKKLQEQEKESAEVLP-------QQQQQHQQQNQAP--------AHKIPAQTVVRRVRALYDLTTNEPDELSFRKGDVITVLEQVYRDWWKGALRGNMGIFPLNYVTPIVEPSKEEIEKEKNKEAIVFSQK--------------------------TTIDQLHNSLNAASKTGNSNEVLQDPHIGDMYGSVTPLRPQVTRMLGKYAKEKEDMLSLRQVLANAERSYNQLMDRAANAHISPPVPGPALYAGMTHANNTPVMPPQ----------RQSYQSNEYSPYP---------------------------SNLPIQHPTNSANNTPQYGYDLGYSVVSQPPPGYEQ---------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : : ***. ::* ***:** * . :: : : :*: : *.:* :::::* : .***. :: *:.*::* : . :: . :: * : :: : :: .:*:* .* : : :::.:. : . . .. .: : : . : * :*. :*:. . : *:***:**: : * :**:* *::* **:: :**** : . *:** *:**. : . * :. ::: : .::.. *: .:. .: : .: .: : * : * ::: :: .* : :* * ** : . : . . .* ** *: : *: . . . * ", "identical_positions": 66, "similar_positions": 137, "identity": "9.54%" }, { "cls_id": "homologset.agr.MGI:1329015", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AYG7-1", "uniprot_id": "NF2IP_RAT", "id": "Q6AYG7-1", "name": "NFATC2-interacting protein", "aln": "MAEPLRRRGPRSRGGRASRGARRARAARGRCPRAPRSPTRLIPDTVLVDLVSDSDEEVLEVV-----ADPGEVPVARLPAPAAPEQDSDSDSEGAAEGPAGAPRTLVRRRRR-LLDPGEAPVVPVYSGKVQSSLNLIPDNSSLLKLCPSEPEDEADLTDSGSPPSED-ALPPGSPWKKKLRKKHEKEEKKMEEFPDQDISPLPQPSSRNKSRKHTEALQKLREVNKRLQDLRSCLSPKQHQSPALQNTDDEVVLVEGSVLPQNPRLFTLKIRCRADLVRLPVKTSEPLQNVVDHMASHLGVSPNRILLLFGETELSPTATPRTLKLGVADIIDCVVLASSSEDTETSQELRLRVQGKEKHQMLEISLSPDSPLKVLMSHYEEAMGLSGHKLSFFFDGTKLSGKELPTDLGLESGDLIEVWG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O09130-1", "uniprot_id": "NF2IP_MOUSE", "id": "O09130-1", "name": "NFATC2-interacting protein", "aln": "MAEPLRGRGPRSRGG---RGARRARGARGRCPRARQSPARLIPDTVLVDLVSDSDEEVLEV------ADPVEVPVARLPAPAKPEQDSDSDSEGAAEGPAGAPRTLVRRRRRRLLDPGEAPVVPVYSGKVQSSLNLIPDNSSLLKLCPSEPEDEADLTNSGSSPSEDDALPSGSPWRKKLRKKCEKEEKKMEEFPDQDISPLPQPSSRNKSRKHTEALQKLREVNKRLQDLRSCLSPKQHQSPALQSTDDEVVLVEGPVLPQSSRLFTLKIRCRADLVRLPVRMSEPLQNVVDHMANHLGVSPNRILLLFGESELSPTATPSTLKLGVADIIDCVVLASSSEATETSQELRLRVQGKEKHQMLEISLSPDSPLKVLMSHYEEAMGLSGHKLSFFFDGTKLSGKELPADLGLESGDLIEVWG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NCF5-1", "uniprot_id": "NF2IP_HUMAN", "id": "Q8NCF5-1", "name": "NFATC2-interacting protein", "aln": "MAEPVGKRGRWSGGSGAGRGGRGGWGGRGRRPRAQRSPSRGTLDVVSVDLVTDSDEEILEVATARGAADEVEVEPPEPPGPVASRDNSNSDSEGEDRRPAGPPREPVRRRRRLVLDPGEAPLVPVYSGKVKSSLRLIPDDLSLLKLYPPGDEEEAELADSSGLYHEG-SPSPGSPWKTKLRTK-DKEEKKKTEFLDLDNSPLSPPSPRTKSRTHTRALKKLSEVNKRLQDLRSCLSPKPPQGQEQQGQEDEVVLVEGPTLPETPRLFPLKIRCRADLVRLPLRMSEPLQSVVDHMATHLGVSPSRILLLFGETELSPTATPRTLKLGVADIIDCVVLTSSPEATETSQQLQLRVQGKEKHQTLEVSLSRDSPLKTLMSHYEEAMGLSGRKLSFFFDGTKLSGRELPADLGMESGDLIEVWG", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****: ** * *. **.* . ..*** *** :**:* *.* ****:*****:*** ** ** .. *.*. ..::*:***** . ***.** ****** :*******:********:***.****: ***** *. *:**:*::*.. *. : ..****:.***.* :***** ** * * ***. **.*.***.**.**:** **************** *. *. :********..**:..***.*************:: *****.******.******.********:******** ***************:**.* *****:*:********** **:*** *****.*************:*************:***:***:**********", "identical_positions": 286, "similar_positions": 73, "identity": "67.93%" }, { "cls_id": "homologset.agr.MGI:1329016", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z2G6-1", "uniprot_id": "SE1L1_MOUSE", "id": "Q9Z2G6-1", "name": "Protein sel-1 homolog 1", "aln": "MQVRVRLSLLLLCAVLLGSAAATSDDKTNQDDSLDSKSSLPTDESVKDHTTTGKVVAGQIFVDSEEAEVESLLQDEEDSSKTQE-----EEISFLESPNPSSKTYEELKRVRKPVLTAIEGTAHGEPCHFPFLFLDKEYDECTSDGREDGRLWCATTYDYKTDEKWGFCETEEDAAKRRQMQEAEMIYQAGMKILNGSNRKSQKREAYRYLQKAAGMNHTKALERVSYALLFGDYLTQNIQAAKEMFEKLTEEG---SPKGQTGLGFLYASGLG-VNSSQAKALVYYTFGALGGNLIAHMILGYRYWAGIGVLQSCESALTHYRLVANHVASDISLTGGSVVQRIRLPDEVENPGMNSGMLEEDLIQYYQFLAEKGDVQAQVGLGQLHLHGGRGVEQNHQRAFDYFNLAANAGNSHAMAFLGKMYSEGSDIVPQSNETALHYFKKAADMG----NPVGQSGLGMAYLYGRGVQVNYDLALKYFQKAAEQGWVDGQLQLGSMYYNGIGVKRDYKQALKYFNLASQGGHILAFYNLAQMHASGTGVMRSCHTAVELFKNVCER--GRWSERLMTAYNSYKDEDYNAAVVQYLLLAEQGYEVAQSNAAFILDQREATIVGE-NETYPR---ALLHWNRAASQGYTVARIKLGDYHFYGFGTDVDYETAFIHYRLASEQQHSAQAMFNLGYMHEKGLGIKQDIHLAKRFYDMAAEASPDAQVPVFLALCKLGVVYFLQYIR--EANIRDLFTQLDMDQLLGPEWDLYLMTIIALLLGTVIAYRQ-RQHQDIPVPRPPGP-------RPAPPQQEGPPEQQPPQ---------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q80Z70-1", "uniprot_id": "SE1L1_RAT", "id": "Q80Z70-1", "name": "Protein sel-1 homolog 1", "aln": "MQVRVRL-LLLLCAVLLGSAAASSDEETNQDESLDSKGALPTDGSVKDHTTGKVVLLARDLLILKDSEVESLLQDEEESSKSQEEVSVTEDISFLDSPNPSSKTYEELKRVRKPVLTAIEGTAHGEPCHFPFLFLDKEYDECTSDGREDGRLWCATTYDYKTDEKWGFCETEEDAAKRRQMQEAEAIYQSGMKILNGSTRKNQKREAYRYLQKAAGMNHTKALERVSYALLFGDYLTQNIQAAKEMFEKLTEEG---SPKGQTGLGFLYASGLG-VNSSQAKALVYYTFGALGGNLIAHMVLGYRYWAGIGVLQSCESALTHYRLVANHVASDISLTGGSVVQRIRLPDEVENPGMNSGMLEEDLIQYYQFLAEKGDVQAQVGLGQLHLHGGRGVEQNHQRAFDYFNLAANAGNSHAMAFLGKMYSEGSDIVPQSNETALHYFKKAADMG----NPVGQSGLGMAYLYGRGVQVNYDLALKYFQKAAEQGWVDGQLQLGSMYYNGIGVKRDYKQALKYFNLASQGGHILAFYNLAQMHASGTGVMRSCHTAVELFKNVCER--GRWSERLMTAYNSYKDDDYNAAVVQYLLLAEQGYEVAQSNAAFILDQREATIVGE-NETYPR---ALLHWNRAASQGYTVARIKLGDYHFYGFGTDVDYETAFIHYRLASEQQHSAQAMFNLGYMHEKGLGIKQDIHLAKRFYDMAAEASPDAQVPVFLALCKLGVVYFLQYIR--EANIRDLFTQLDMDQLLGPEWDLYLMTIIALLLGTVIAYRQ-RQHQDIPVPRPPGP-------RPAPPQQEGPPEQQPPQ---------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UBV2-1", "uniprot_id": "SE1L1_HUMAN", "id": "Q9UBV2-1", "name": "Protein sel-1 homolog 1", "aln": "MRVRIGL-TLLLCAVLLSLASASSDEEGSQDESLDSKTTLTSDESVKDHTTAGRVVAGQIFLDSEESELESSIQEEEDSLKSQEGESVTEDISFLESPNPENKDYEEPKKVRKPALTAIEGTAHGEPCHFPFLFLDKEYDECTSDGREDGRLWCATTYDYKADEKWGFCETEEEAAKRRQMQEAEMMYQTGMKILNGSNKKSQKREAYRYLQKAASMNHTKALERVSYALLFGDYLPQNIQAAREMFEKLTEEG---SPKGQTALGFLYASGLG-VNSSQAKALVYYTFGALGGNLIAHMVLGYRYWAGIGVLQSCESALTHYRLVANHVASDISLTGGSVVQRIRLPDEVENPGMNSGMLEEDLIQYYQFLAEKGDVQAQVGLGQLHLHGGRGVEQNHQRAFDYFNLAANAGNSHAMAFLGKMYSEGSDIVPQSNETALHYFKKAADMG----NPVGQSGLGMAYLYGRGVQVNYDLALKYFQKAAEQGWVDGQLQLGSMYYNGIGVKRDYKQALKYFNLASQGGHILAFYNLAQMHASGTGVMRSCHTAVELFKNVCER--GRWSERLMTAYNSYKDGDYNAAVIQYLLLAEQGYEVAQSNAAFILDQREASIVGE-NETYPR---ALLHWNRAASQGYTVARIKLGDYHFYGFGTDVDYETAFIHYRLASEQQHSAQAMFNLGYMHEKGLGIKQDIHLAKRFYDMAAEASPDAQVPVFLALCKLGVVYFLQYIR--ETNIRDMFTQLDMDQLLGPEWDLYLMTIIALLLGTVIAYRQ-RQHQDMPAPRPPGP-------RPAPPQQEGPPEQQPPQ---------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5RIK6-1", "uniprot_id": "Q5RIK6_DANRE", "id": "Q5RIK6-1", "name": "Protein sel-1 homolog 1", "aln": "MNSAKKSCLVLIVALAVTLEVTAG--EVPSDDGVGEGG----DSQSTAENEGANIVTGRAYVP-KDAQTDSSTTDTDMEIKVDE----IEKEDLPSQPPPPQERSKEVPVVNG-------GTASGEPCIFPFLFQGKEYSDCTTEGRGDGRLWCATTYDYNNDKRWGFCETEEQAEQRRMAEEAEEQYQATVRMINGTNRRSQKKELFDKLLQVAEMGHTKAMEKVAYAMLFGDYLPQSIPQAKEMFEKLALEG---SPKAQTALGFLYAAGLG-VNSSQAKALVYYTFGALGGNLVAHMILGYRYWGGVGVPQSCESALTHYRLVANHVASDVSLTGGSAVQRIRLLDEVENPGSSSGMLEEDLIQYYQFLAEKGDVQAQVGLGQLHLHGGRGVEQNHQRAYEYFNQAANAGNTHAMAFLGKMYSEGSEYVPQNNETALHYFKKAADLG----NPVGQSGLGMAYLYGRGVPVNYDLALKYFQKAAEQGWVDGQLQLGTMYYNGIGVKRDYKQALKFFNLASQAGHILAFYNLAQMHATGTGVMRSCHTAVELFKNVCER--GRWSERLMAAYRSFKEGDMDSALIQYLLLAEQGYEVAQSNVAFVLDQKGSQIFNE-NETYPR---ALLHWTRAAAQGYTVARIKLGDYHFYGYGTDVDYETAVIHYRLASEQQHSAQAMFNLGYMHEKGLGIKQDIHLAKRFYDMAAEASPDAQVPVFLALCKLGLVYALQYLQ--DLNLKEVLSQVDLDQLLGPEWDLYLMTVIALLLGTVIAYRQ-RQHQAVPR-APAAP-------NRPPAQPEQPAEEPEEQ---------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V415-1", "uniprot_id": "Q9V415_DROME", "id": "Q9V415-1", "name": "", "aln": "---MKANSWMCLLALLLAWQLRAEELQGPNIDGTGSSLGSATGTGTGTGLGTGTATPTLPNEPSTQAEAEEVTTAESESRVPSE-----SNERKADKPKESTKFASRTK-------------------VMPASLFERLWNES---------LIRRQKLKAEIERIEAKRKSTEVLELTPDQIEAQTVYDNAMDMLAKPS--TDKRVAMILLKKAAAFNHLKARAELAWAALLGQWMDFDFNHAVDEFESLANEG---VPEAHMGLGFLYSVGVGGKNVSQPLALIHYSLAALGDNTPAQMAMGYRYLYGINVPISCEKALIHYKRVAKKVASKITFANGPVVHRVRLLDDLENPGSS----ETEIVDYYKLLADKGDIQSQVGLGQVYYQGGKVTEQDHQKALEYFKMAADAGSAVGIAFLGKLYLEGSDQIRADNDAAFGYFSKAAEMG----DPVGQSGLGLMYLKGLGVPKDSIKALSYFTQAADQGWVDGQLQLGNMYFTGNGVKTDYKLAFKYFNLATQSGHVLAYYNLGVMNAYGMGMLRSCPAAVEFFKTVSER--GRWSSRLMMAYSDYKNNRIDEAYMQYSLMAEMGYEVAQSNAAFLLDRKEVHVFNDRHEDLIR---AFYYWKRAAGQGYSAAQVKLGDYYYYGWGTSTDFETAAALYRKASEQQYNAQAMFNLGYMHEQGLGMKKDWHLAKRLYDLAAETNSDAKVPVAIALFKLQMLATIESIK--ESPYRFIFY---MDENIAANWDLYMITVLTLLLGIIMYMRRPFQQPDQPAQQPAADDIAAAPVNLAPVGAEAAPVAAVVEGVGVTPPAAAVSSHDAVAASSSTETSSTTATSLVDAASQGGSGTTSAAPDGANTLDPTG----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q05787-1", "uniprot_id": "HRD3_YEAST", "id": "Q05787-1", "name": "ERAD-associated E3 ubiquitin-protein ligase component HRD3", "aln": "-MITLLLYLCVICNAIVLIRADSIADPWPEARHLLNTIAKSRDPMKEAAMEPNADEFVGFYVPMDYSPRNEEKNYQSIWQNEITD----SQRHIYELLVQSSEQFNNSE----------------ATYTLSQIHLWSQYNFPHN-------MTLAHKYLEKFNDLTHFTNHSAIFDLAVMYATGGCASGNDQTVIPQDS-----AKALLYYQRAAQLGNLKAKQVLAYKYYSGFNVPRNFHKSLVLYRDIAEQLRKSYSRDEWDIVFPYWESYNVRISDFESGLLGKGLNSVPSSTVRKRTT----RPDIGSPFIAQVNGVQMTLQIEPMGRFAFNGNDGNINGDEDDEDASE--------RRIIRIYYAALNDYKGTYSQSRNCERAKNLLELTYKEFQPHVDNLDPLQVFYYVRCLQLLGHMYFTGEGSSKPNIHMAEEILTTSLEISRRAQGPIGRACIDLGLIN-QYITNNISQAISYYMKAMKTQANNGIVEFQLSKLATSFPEEKIGDPFNLMETAYLNGFIPAIYEFAVMIESGMNSKSSVENTAYLFKTFVDKNEAIMAPKLRTAFAALINDRSEVALWAYSQLAEQGYETAQVSAAYLMYQLPYEFEDPPRTTDQRKTLAISYYTRAFKQGNIDAGVVAGDIYFQ----MQNYSKAMALYQGAALK-YSIQAIWNLGYMHEHGLGVNRDFHLAKRYYDQVSEHDHRFYLASKLSVLKLHLKSWLTWITREKVNYWKPSSPLNPNEDTQHSKTSWYKQLTKILQRMRHKEDSDKAAEDSHKHRTVVQNG----ANHRGDDQEEASEILGFQMEDLVTMGCILGIFLLSILMSTLAARRGWNVRFNGAQLNANGNRQQEQQQQQQAQGPPGWDFNVQIFAI", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : . . . : :. . .. . : .. :. :. : . : : : . :: . :.* :.: ** ::: * : .: : :..:: : .. . : * * . . . .*: : :: .. : .:. .: : : :. .. :: . :: .: . : ** * : . :* : : . . ::.* : :. : :**::* *. . . * :..: ::. .*:*:: :.: : : : *:.*: :* . :* ::: : . .:: :: * *.: * *::. * * . * :. :**.. :: . : :* *: : : * * :** ***.** ..*::: : . . . * *: ::.** ** * : ** :: ::..* *: *: : :. **::*******:***:::* ***** ** .:* . :. ::: ** : : : . :: . : : :* . . * .. : ", "identical_positions": 81, "similar_positions": 210, "identity": "9.12%" }, { "cls_id": "homologset.agr.MGI:1329019", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QZK8-1", "uniprot_id": "DNS2A_RAT", "id": "Q9QZK8-1", "name": "Deoxyribonuclease-2-alpha", "aln": "MAAPSSLLLAALLWVP---AEALSCYGDSGRPVDWFVVYKLPANSGS--GDKPWKGLMYKYMD-QNSEGWQDGVGHIDSKDGAVGLTLQPLYQKNSSQLAFLLYNDQPPKSSSAQDSSSRGHTKGVLLLDQEGGFWLVHSVPRFPSPASSGAYSWPPNARTYGQTLLCVSLPFSQFPGIGKQLTYTYPLVYDHK--LEGIFAQKLPDLEEVTKGHHVLREPWNSSVILTSRAGTTFQSFAKFGKFGDDLYSGWLAAALGTNLQVQFWPNSPGILPSNCSGTHKILDVTETGFPGPSGPTFNATEDHSKWCVAP------------EGPWVCVGDMNRNKRETHRGGGTLCTQVPALWKAFRSLVKACKPC-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P56542-1", "uniprot_id": "DNS2A_MOUSE", "id": "P56542-1", "name": "Deoxyribonuclease-2-alpha", "aln": "MATLRSLLLAALLWVP---AEALSCYGDSGQPVDWFVVYKLPAHSGS--RDTP-KGLTYKYMD-QNSDGWQDGVGYINSSEGAVGRSLQPLYRKNSSQLAFLLYNDQPPKSSSARDSTGHGHTKGVLLLDQEGGFWLVHSVPRFPPPASSGAYTWPPNAQTFGQTLLCVSLPFTQFARIGKQLTYTYPLVYDHK--LEGFFAQKLPDLETVIKNQHVLHEPWNSSVILTSQAGATFQSFAKFGKFGDDLYSGWLAEALGTNLQVQFWQNSPGILPSNCSGAYQVLDVTQTGFPGPSRLTFSATEDHSKWCVAP------------QGPWACVGDMNRNKAETHRGGGTVCTQLPSFWKAFQSLVKDWKPCIEGS---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00115-1", "uniprot_id": "DNS2A_HUMAN", "id": "O00115-1", "name": "Deoxyribonuclease-2-alpha", "aln": "---MIPLLLAALLCVP---AGALTCYGDSGQPVDWFVVYKLPALRGS--GEAAQRGLQYKYLD-ESSGGWRDGRALINSPEGAVGRSLQPLYRSNTSQLAFLLYNDQPPQPSKAQDSSMRGHTKGVLLLDHDGGFWLVHSVPNFPPPASSAAYSWPHSACTYGQTLLCVSFPFAQFSKMGKQLTYTYPWVYNYQ--LEGIFAQEFPDLENVVKGHHVSQEPWNSSITLTSQAGAVFQSFAKFSKFGDDLYSGWLAAALGTNLQVQFWHKTVGILPSNCSDIWQVLNVNQIAFPGPAGPSFNSTEDHSKWCVSP------------KGPWTCVGDMNRNQGEEQRGGGTLCAQLPALWKAFQPLVKNYQPCNGMARKPSRAYKI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VED8-1", "uniprot_id": "Q9VED8_DROME", "id": "Q9VED8-1", "name": "", "aln": "MRSLCFVLLFVWFFYQNEAKSKVSCKDEAGNDVDWWHLYKLPKHYQHNDLGKDTSGLKYLYVTSQNYDTWQMSGKFISDPLSLPAQTLNPLN-DDPSHTLLAAYNDQQPNGTVFSSG---GHAKGVVASDGETAIWIVHSVPKFP---TIPDYSYPTSGEQYAQSMLCVTLKGEDLEKVGQILVYNEPHFYYQRNPLATRSDELFPSLERALHGQWRTESPFQKDLEVRSLDGKKFRLFGKSGRANVELYADVVAPTLDVSLFVEAWRDGAGNLPNSCDKSDKVLNVESISNPELS-VDFKTTQDHSKWAVSRPTGILIYHWRVGGGDWICVGDINRQEGQLHRGGGTVCHKSARVSNLYRQLVTNYDKCAQQE---------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :** . : ::* .::*. ***: :**** ** * *: :. *: . *.. . . :*:** .:.*: : **** *: : .. **:***: * : .:*:*****.** : *::* .. :.*::***:: :: :*: *.*. * .* : * : :*.** . :.: ..*::..: : * * *: *.* .: . :**:. :* :*...* *: * . * **..*. ::*:* . . * : *.:*:*****.*: * * ****:**:: : :*****:* : . . : :: **. . * ", "identical_positions": 100, "similar_positions": 115, "identity": "26.11%" }, { "cls_id": "homologset.agr.MGI:1329021", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6MG62-1", "uniprot_id": "MSH5_RAT", "id": "Q6MG62-1", "name": "MutS protein homolog 5", "aln": "-----MAFRATPGRTPPGPGP--GVPSASFSSPQPAMAAPGGIEEE-----DEEEPAEIHLCVLWSSGYLGIAYYDTSDSTIHFMP-------------------DAPDHESLKLLQRVLDEINPQSVVTSAKQDEAMTQFLGKLASQEHREPKRPEIILLPSVDFGPEISKQRLLSGNYSFISESMTATEKILFLSSIIPFDCVLTVRALGGLLKFLSRRR--VGVELEDYSVGVPILGFKKFVLTHLVSIDQDTYSVLQIFKSESHPSVYKVASGLKEGLSLFGILNRCRCRWGQKLLRLWFTRPTRELRELNSRLDVIEFFLMPQNLDMAQMMHRLLSHIKNVPLILKRMKLSHTKVSDWQVLYKTVYSALGLRDACRSLPQS---IQLFRDITQEFSD-DLHHIASLIGKVVDFEESLAENRFTVLPNIDPEIDAKKRRLMGLPSFLTEVAQKELENLDSCIPS------------CSVIYIPLIGFLLSIPRLSFMVEASDFEIEGLDFMFLSEDKLHYRSARTKELDALLGDLHCEIRDQEMLLMHQLQCQVLARAPVLTRVLDLASRLDVLLALASAARDYGYSRPHYSPCIQGVRIKNGRHPLMELCARTFVPNSTDCGG-----------DQGRVKVITGPNSSGKSIYLKQVGLITFMALVGSFVPAEEAEIGVIDAIFTRIHSCESISLGLSTFMIDLNQVAKAVNNATEHSLVLIDEFGKGTNSVDGLALLTAVLRHWLALGPSCPHIFVATNFLSLVQLQLLPQ-----------------GPLVQYLTMETCEDGNDLVFFYQLCHGVASASHASYTAAQAGLPDPLIARGKEVSDSIRSGKPVKPMHELVRRTQM---ENCQALVDKFLKLDLEDPSLDLDIFISQEVLPAATTIL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QUM7-1", "uniprot_id": "MSH5_MOUSE", "id": "Q9QUM7-1", "name": "MutS protein homolog 5", "aln": "-----MAFRATPGRTPPGPGPRSGIPSASFPSPQPPMAGPGGIEEE-----DEEEPAEIHLCVLWSSGYLGIAYYDTSDSTIHFMP-------------------DAPDHESLKLLQRVLDEINPQSVVTSAKQDEAMTRFLGKLASEEHREPKGPEIILLPSVDFGPEISKQRLLSGNYSFISDSMTATEKILFLSSIIPFDCVLTVRALGGLLKFLSRRR--IGVELEDYDVGVPILGFKKFVLTHLVSIDQDTYSVLQIFKSESHPSVYKVASGLKEGLSLFGILNRCRCKWGQKLLRLWFTRPTRELRELNSRLDVIQFFLMPQNLDMAQMLHRLLSHIKNVPLILKRMKLSHTKVSDWQVLYKTVYSALGLRDACRSLPQS---IQLFQDIAQEFSD-DLHHIASLIGKVVDFEESLAENRFTVLPNIDPDIDAKKRRLIGLPSFLTEVAQKELENLDSRIPS------------CSVIYIPLIGFLLSIPRLPFMVEASDFEIEGLDFMFLSEDKLHYRSARTKELDTLLGDLHCEIRDQETLLMYQLQCQVLARASVLTRVLDLASRLDVLLALASAARDYGYSRPHYSPCIHGVRIRNGRHPLMELCARTFVPNSTDCGG-----------DQGRVKVITGPNSSGKSIYLKQVGLITFMALVGSFVPAEEAEIGVIDAIFTRIHSCESISLGLSTFMIDLNQVAKAVNNATEHSLVLIDEFGKGTNSVDGLALLAAVLRHWLALGPSCPHVFVATNFLSLVQLQLLPQ-----------------GPLVQYLTMETCEDGEDLVFFYQLCQGVASASHASHTAAQAGLPDPLIARGKEVSDLIRSGKPIKATNELLRRNQM---ENCQALVDKFLKLDLEDPTLDLDIFISQEVLPAAPTIL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43196-1", "uniprot_id": "MSH5_HUMAN", "id": "O43196-1", "name": "MutS protein homolog 5", "aln": "----MASLGANPRRTPQGPRP--GAASSGFPSPAP-VPGPREAEEEE--VEEEEELAEIHLCVLWNSGYLGIAYYDTSDSTIHFMP-------------------DAPDHESLKLLQRVLDEINPQSVVTSAKQDENMTRFLGKLASQEHREPKRPEIIFLPSVDFGLEISKQRLLSGNYSFIPDAMTATEKILFLSSIIPFDCLLTVRALGGLLKFLGRRR--IGVELEDYNVSVPILGFKKFMLTHLVNIDQDTYSVLQIFKSESHPSVYKVASGLKEGLSLFGILNRCHCKWGEKLLRLWFTRPTHDLGELSSRLDVIQFFLLPQNLDMAQMLHRLLGHIKNVPLILKRMKLSHTKVSDWQVLYKTVYSALGLRDACRSLPQS---IQLFRDIAQEFSD-DLHHIASLIGKVVDFEGSLAENRFTVLPNIDPEIDEKKRRLMGLPSFLTEVARKELENLDSRIPS------------CSVIYIPLIGFLLSIPRLPSMVEASDFEINGLDFMFLSEEKLHYRSARTKELDALLGDLHCEIRDQETLLMYQLQCQVLARAAVLTRVLDLASRLDVLLALASAARDYGYSRPRYSPQVLGVRIQNGRHPLMELCARTFVPNSTECGG-----------DKGRVKVITGPNSSGKSIYLKQVGLITFMALVGSFVPAEEAEIGAVDAIFTRIHSCESISLGLSTFMIDLNQVAKAVNNATAQSLVLIDEFGKGTNTVDGLALLAAVLRHWLARGPTCPHIFVATNFLSLVQLQLLPQ-----------------GPLVQYLTMETCEDGNDLVFFYQVCEGVAKASHASHTAAQAGLPDKLVARGKEVSDLIRSGKPIKPVKDLLKKNQM---ENCQTLVDKFMKLDLEDPNLDLNVFMSQEVLPAATSIL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B4N7-1", "uniprot_id": "A0A8M2B4N7_DANRE", "id": "A0A8M2B4N7-1", "name": "MutS protein homolog 5", "aln": "------MYRVADDSILPQPES----------------RAPSVMNED-----EDGRNREIILSVLLKQGNIGLSYYDSRDYTLHYMP-------------------DTVENSDLYLLDRVIQELSPTVIISSAKQEQCLVRFLEKLES--NCDEYKPEIVIFPSANFGVEVSKQRLISAHLPLLSSTITESEKILYISSCIPLDSGVMVRSIGGLLKCVEKRR--IGSELEDNDVGIPILQFLTYTLQDVVYIDRDTYSALQIFKSELHPSVLKLQSGVKEGLSLYGILNQCRSKYGSLLLRQWLHRPTRDLNILNRRQEVIRFFTSPRNFADLCTLQSCLRSIKNISMLLHKMSLCNPKVAVWQSLYKTVYSAVCIRDTIRSLPQS---IQLFREISENFTD-DLFYIATYISKVVDFEGSISENRFTVRPNVDPVIDEKKRRMMGLPDFLTDVARAELENLDPRFST------------CSVIYMPLIGFLLTVPRLPSMLDKQSFEIAGLDFIFLSKDQLHYRSTRTKELDSMLGDLHCDILDLEMAVMRKLQASVLQRSDCMYKVMSLCAELDCLIALAQASREHGYCCPILTTEHRLALIES-RHPLLELCTSVFVSNTYISSE-----------TEGKVKVITGPNSSGKSIFLKQVGLIVFMALIGSNVPAKEAEIGLVDGIFTRMHSRESISVGLSTFMIDVNQMAHSLNHSTENSLVLVDEFGKGTNTVDGLSLLVSCLSHWLRRGLQCPHLLMSTCFHSLIQLGLIPD-----------------SSLLALLTLETAIEGDELVFLYQVKNGICQSSCAANIATLAGIPDDLVRRGVEVSDLYRTGRTIRKMERPSADEQN---NRCAEIVEKFLSIDLDDPELDPDLLLKDQMLPALEEVL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q12175-1", "uniprot_id": "MSH5_YEAST", "id": "Q12175-1", "name": "MutS protein homolog 5", "aln": "MSHEWLISASETMRSIGNGEGLRDKGAVVANNDGEFNEGDTNREEDSSTIFSFDFDEEIVMCIDFSGGKLGCSILDYHTKTLKAFDQDYVVNKTTISSHDLIDDADMSSNDISLLLGLLIMEANPTVCLVPARLEDWIFDYIKTKCDEINCRLELQPIKRFKKWDL---LQSLQLRGHDNQTILNDILSNSKFTTTVTLGTVGCILANHEQLGEYNDSTASSNMVTGRLVQNAFEDVIHGIRYIDIRDRMVLDENTISALHIFPTAHKLGHDKMMR--NGFFSVFELFNQVSSDYARRILKSWLINPLTNKKRIETRYSIIRTLLDKQNAIIFSDLSQSIKRCPDAFGFINQLRSGKSTLGTWSKVASFLEKGIAIFQLVSSLKLGSDEANILHDIKNKVDISALKECLRKVETVIDFDTSRDTKTLTINTGVDNRLDECRNIYNHLEGILLDVARETQIFLLNTMPQEDCKTTKSLEKLVNAVYIPQLGYLVTISVLMEPLLDG-IPNLQWEEIFRSSENIYFKNGRVLELDETYGDIYGAISDFEIEILFSLQEQILRRKTQLTAYNILLSELEILLSFAQVSAERNYAEPQLVEDECILEIINGRHALYETFLDNYIPNSTMIDGGLFSELSWCEQNKGRIIVVTGANASGKSVYLTQNGLIVYLAQIGCFVPAERARIGIADKILTRIRTQETVYKTQSSFLLDSQQMAKSLSLATEKSLILIDEYGKGTDILDGPSLFGSIMLN-MSKSEKCPRIIACTHFHELFNENVLTENIKGIKHYCTDILISQKYNLLETAHVGEDHESEGITFLFKVKEGISKQSFGIYCAKVCGLSRDIVERAEELSRMINRGDDVVQQCGNLTEKEMREFQKNQEIVKKFLSWDLDLETTTTSENLRLKLKNFLR---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :*: . ** :.: . * :* : * *:: : * .:. ** :: * .* : .*: :: : :: . . : * : . :: :.. :* . . : . : ..*: : .... : : * : : .* : . * : : . : :*.:* *.*:** : : . *: : :*:: ::*: . :. :*: *: .* : :. * .:*. : :* : : : ::::: :..:. *. : . : ..: : : ** . :::::* ::. * : .*:**: * : :*: ..:* :* :. * .:* :**: * :. ..:*:* :*:*:::. * : : : :* *.::::::. *. *** **:: * * * :: .** .:* * : * :.*: *:::*..: : .*. * * . **.* * ::.*: . :*:: *:**.*:****::*.* ***.::* :*. ***:.*.** * *:**::: *:: *:*::* :*:*:::. :* :**:*:**:****: :** :*: : : : : . **::: .* * .*.: ::.: *: : :.: :.*:::: .*:.. * . * .*:. :: *. *:* . * : : :. :*.**:. **: . : :: ", "identical_positions": 148, "similar_positions": 287, "identity": "16.25%" }, { "cls_id": "homologset.agr.MGI:1329025", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35474-1", "uniprot_id": "EDIL3_MOUSE", "id": "O35474-1", "name": "EGF-like repeat and discoidin I-like domain-containing protein 3", "aln": "MKHLVAAWLLVGLSLGVPQ-FGKGDICNPNPCENGGICLSGLADDSFSCECPEGFAGPNCSSVVEVASDEEKPTSAGPCIPNPCHNGGTCEISEAYRGDTFIGYVCKCPRGFNGIHCQHNINECEAEPCRNGGICTDLVANYSCECPGEFMGRNCQYKCSGPLGIEGGIISNQQITASSTHRALFGLQKWYPYYARLNKKGLINAWTAAENDRWPWIQINLQRKMRVTGVITQGAKRIGSPEYIKSYKIAYSNDGKTWAMYKVKGTNEEMVFRGNVDNNTPYANSFTPPIKAQYVRLYPQICRRHCTLRMELLGCELSGCSEPLGMKSGHIQDYQITASSVFRTLNMDMFTWEPRKARLDKQGKVNAWTSGHNDQSQWLQVDLLVPTKVTGIITQGAKDFGHVQFVGSYKLAYSNDGEHWMVHQDEKQRKDKVFQGNFDNDTHRKNVIDPPIYARFIRILPWSWYGRITLRSELLGCAEEE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6GKH0-1", "uniprot_id": "A0A8I6GKH0_RAT", "id": "A0A8I6GKH0-1", "name": "", "aln": "MKHLVAAWLLVGL-LGVPQ-FVKGDICNPNPCENGGICLSGLADDSFSCECPDGFTDPNCSSVVEVG----------PCIPNPCHNGGTCEISEAYRGDTFIDYVCKCPQGFNGIHCQHNINECEAEPCRNGGICTDLVANYSCECPGEFMGRNCQYKCSGPLGIEGGIISNQQITASSTHRALFGLQKWYPYYARLNKKGLINAWTAAENDRWPWIQINLQRKMRVTGVITQGAKRIGSPEYIKSYKIAYSNDGKTWAMYKVKGTNEEMVFRGNVDNNTPYANSFTPPIKAQYVRLYPQICRRHCTLRMELFGCELSGCSEPLGMKSGHIQDYQITASSIFRTLNMDMFTWEPRKARLDKQGKVNAWTSGHNDQSQWLQVDLLVPTKVTGIITQGAKDFGHVQFVGSYKLAYSNDGEHWTVYQDAKQRKDKVFQGNFDNDTHRKNVIDPPIYARHIRILPWSWYGRITLRSELLGCTEEE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O43854-1", "uniprot_id": "EDIL3_HUMAN", "id": "O43854-1", "name": "EGF-like repeat and discoidin I-like domain-containing protein 3", "aln": "MKRSVAVWLLVGLSLGVPQ-FGKGDICDPNPCENGGICLPGLADGSFSCECPDGFTDPNCSSVVEVASDEEEPTSAGPCTPNPCHNGGTCEISEAYRGDTFIGYVCKCPRGFNGIHCQHNINECEVEPCKNGGICTDLVANYSCECPGEFMGRNCQYKCSGPLGIEGGIISNQQITASSTHRALFGLQKWYPYYARLNKKGLINAWTAAENDRWPWIQINLQRKMRVTGVITQGAKRIGSPEYIKSYKIAYSNDGKTWAMYKVKGTNEDMVFRGNIDNNTPYANSFTPPIKAQYVRLYPQVCRRHCTLRMELLGCELSGCSEPLGMKSGHIQDYQITASSIFRTLNMDMFTWEPRKARLDKQGKVNAWTSGHNDQSQWLQVDLLVPTKVTGIITQGAKDFGHVQFVGSYKLAYSNDGEHWTVYQDEKQRKDKVFQGNFDNDTHRKNVIDPPIYARHIRILPWSWYGRITLRSELLGCTEEE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IMA9-1", "uniprot_id": "A0A0R4IMA9_DANRE", "id": "A0A0R4IMA9-1", "name": "", "aln": "-MGPLLVSIALCVHLAVPH-LVKA--------ADG--------------------EDPTSAG---------------PCHPNPCHNGGICEISETFRGDTFIGYVCKCPSGFNGIHCQHNVNECERSPCRNGGICTDLVANYSCECPGEYMGRNCQYKCSGPLGMEGGIISNQQITASSTHRALFGLQKWYPYFARLNKKGLVNAWTAAENDRWPWIQINLQRRMRVTGVITQGAKRIGSPEYVKSYKVAYSDDGKTWRTYKVKGTDEDIIFRGNIDNNTPFANSFTPPIEAQYVRIYPQVCRRHCTLRMELLGCELSGCSEPMGMKSGHIQDYQITASSIFRTLNMDMFTWEPGKARLDKQGKVNAWTSGHSDQSQWLQVDMLRPTKITGIITQGAKDFGHVQFVGSYKVAYSNNGERWLIYQDEKQKKDKVFQGNFDNDTHRKNVIDPPIYARFVRILPWSWYGRITLRAELLGCTEEE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1Q6J1-1", "uniprot_id": "F1Q6J1_DANRE", "id": "F1Q6J1-1", "name": "", "aln": "-MLPVFLLLFVRTGASLPHPTSAGEVCEPVPCENS-------------ADCPTTPADENGSSASDWK----EQSIIGPCRPNPCHNGGLCELNQTDRGDALLGYLCRCPAGFNGVHCQHNVNECEKNPCRNGGSCTDLQANYTCLCPGEYMGQNCQYKCSGPLGMEGGIISNQQITASSTHRALFGLQKWFPYFARLNKKGLVNAWSAAEGDRYPWIQINLLRRMRVTALITQGAKRIGSPEYVKSFKVAYSEDGKAWSLFKVKGTDEDMIFTGNTDNSSPSVNSFSPPIEAQYIRVYPQICRKHCTLRMELLGCELTGCSEPMGMKTGHIQDYQLSSSSVFQTLSMDMFSWDPSKARLDKQGKVNAWTSAHNDQSQWLQIDLLIPTKVTGIITQGAKDFGHVQFVGSFKLAFSNDGEKWIIYQDEKQHKDKIFQGNFDNETHRKNVIDPPIYARFVRILPWSWYGRITVRMELLGCPEEQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : .:*: . :. . . :. ** ******** **:.:: ***:::.*:*:** ****:*****:**** .**:*** **** ***:* ****:**:***********:*************************:**:********:***:***.**:******* *:****.:*************:**:*:***:***:* :*****:*:::* ** **.:* .***:***:***:*:***:**:********:****:*****:***:*******:::**:*:**.****:*:* ***************.*.*******:*:* ***:*******************:*:*:**:**:* ::** **:***:*******:**************.:************:* *****.**:", "identical_positions": 308, "similar_positions": 91, "identity": "64.03%" }, { "cls_id": "homologset.agr.MGI:1329026", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P51800-1", "uniprot_id": "CLCKA_HUMAN", "id": "P51800-1", "name": "Chloride channel protein ClC-Ka", "aln": "-------------------------------------------MEELVGLREGFSGDPVTLQELWG--------------PCPHIRRAIQGG----------------------------------LEWLKQK-------------------------------VFRLGEDWYFLMTLGVLMALVSYAMNFAIGCVVRAHQWLYREIGDSHLLRYLSWTVYPVALVSFSSGFSQSITPSSGGSGIPELKTMLAGVILEDYLDIKNFGAKVVGLSCTLATGSTLFLGKVGPFVHLSVMIAAYLGRVRTTTIGEPENKSKQNEMLVAAAAVGVATVFAAPFSGVLFSIEVMSSHFSVRDYWRGFFAATCGAFIFRLLAVFNSEQETITSLYKTSFRVDVPFDLPEIFFFVALGGICGVLSCAYLFCQRTFLSFIKTNRYSSKLLATSKPVYSALATLLLASITYPPGVGHFLASRLSMKQHLDSLFDNHSWALMTQNSSPPWPEELDPQHLWWEWYHPRFTIFGTLAFFLVMKFWMLILATTIPMPAGYFMPIFILGAAIGRLLGEALAVAFPEGIVTGGVTNPIMPGGYALAGAAAFSGAVTHTISTALLAFELTGQIVHALPVLMAVLAANAIAQSCQPSFYDGTIIVKKLPYLPRILGRNIGSHHVRVEHFMNHSITTLAKDTPLEEVVKVVTS-TDVTEYPLVESTESQILVGIVQRAQLVQALQAEPP----------------------------------------------------------------------SRAP--------------------GHQ-----------------------------------------------------------------------------------------------------------------------------------------------QCLQDILARGCPT--------------------------------------------------------------------------EPVTLTLFSETTLHQAQNLFKLLNLQSLFVTSRGRAVGCVSWVEMKKAISNLTN----PPAPK----------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P51801-1", "uniprot_id": "CLCKB_HUMAN", "id": "P51801-1", "name": "Chloride channel protein ClC-Kb", "aln": "-------------------------------------------MEEFVGLREGSSGNPVTLQELWG--------------PCPRIRRGIRGG----------------------------------LEWLKQK-------------------------------LFRLGEDWYFLMTLGVLMALVSCAMDLAVESVVRAHQWLYREIGDSHLLRYLSWTVYPVALVSFSSGFSQSITPSSGGSGIPEVKTMLAGVVLEDYLDIKNFGAKVVGLSCTLACGSTLFLGKVGPFVHLSVMMAAYLGRVRTTTIGEPENKSKQNEMLVAAAAVGVATVFAAPFSGVLFSIEVMSSHFSVWDYWRGFFAATCGAFMFRLLAVFNSEQETITSLYKTSFRVDVPFDLPEIFFFVALGGLCGILGSAYLFCQRIFFGFIRNNRFSSKLLATSKPVYSALATLVLASITYPPSAGRFLASRLSMKQHLDSLFDNHSWALMTQNSSPPWPEELDPQHLWWEWYHPRFTIFGTLAFFLVMKFWMLILATTIPMPAGYFMPIFVYGAAIGRLFGETLSFIFPEGIVAGGITNPIMPGGYALAGAAAFSGAVTHTISTALLAFEVTGQIVHALPVLMAVLAANAIAQSCQPSFYDGTVIVKKLPYLPRILGRNIGSHRVRVEHFMNHSITTLAKDMPLEEVVKVVTS-TDVAKYPLVESTESQILVGIVRRAQLVQALKAEPP----------------------------------------------------------------------SWAP--------------------GHQ-----------------------------------------------------------------------------------------------------------------------------------------------QCLQDILAAGCPT--------------------------------------------------------------------------EPVTLKLSPETSLHEAHNLFELLNLHSLFVTSRGRAVGCVSWVEMKKAISNLTN----PPAPK----------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q06393-1", "uniprot_id": "CLCKA_RAT", "id": "Q06393-1", "name": "Chloride channel protein ClC-Ka", "aln": "-------------------------------------------MEELVGLREGSSGKPVTLQELWG--------------PCPRIRRGVRRG----------------------------------LEWLKER-------------------------------LFRVGEDWHFLVALGVLMALISYAMNFAIGRVVRAHKWLYREVGDGHLLRYLSWTVYPVALLSFSSGFSQSISPFSGGSGLPELKTMLSGVVLEDYLDIKNFGAKVVGLSCTLATGSTIFLGKVGPFVHLSVMISAYLGRVRAKTIGETENKAKEIEMLSAAAAVGVATVFAAPFSGVLFSIEVMSSHFSVWNYWRGFFAATCGAFMFRLLGVFNSEQETITSIYKTRFRVDVPFDLPEIFFFVALGFICGVLSCAYLFCQRTFLRFIKTNRYTSRLLATSKPSYAALVALVLASITYPPGVGRFMASRLSMAEHLHSLFDNNSWALMTRNSSPPWPAEPDPQNLWLEWCHPRFTIFGTLAFFLVMKFWMLILATTIPMPAGYFMPIFIIGAAIGRLLGEALSVAFPEGIVAGREVNPIMPGGYALAGAAAFSGAVTHTISTALLAFELTGQIVHALPVLMAVLAANAISQNCQPSFYDGTIMAKKLPYLPWIRGRQIGSYPVTVEHFMNCNLTTLAKDTPLEEVVKVVTS-TEVSQYPLVETRESQTLVGIVERTHLVQALQTQPA----------------------------------------------------------------------SWAP--------------------GQE-----------------------------------------------------------------------------------------------------------------------------------------------RFLQDILAGGCPT--------------------------------------------------------------------------QPVTLQLSPETSLYQAHSLFERLTLQSLFVTSRGKAVGSVSWAELKKAISTLIN----PPAPK----------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WUB7-1", "uniprot_id": "CLCKA_MOUSE", "id": "Q9WUB7-1", "name": "Chloride channel protein ClC-Ka", "aln": "-------------------------------------------MEELVGLREGSSGKPVTLQELWG--------------PCPRIRRGIRGG----------------------------------LEWLKER-------------------------------LFRAREDWYFLVALGVLMALISYAMNFAIGRVVRAHKWLYREVGDGHLLRYLSWTVYPVALLSFSSGFSQSITPFSGGSGLPELKTMLSGVVLENYLDIKNFGAKVVGLSCTLATGSTIFLGKVGPFVHLSVMISAYLGRVRAKAVGDTESKAKEVEMLSAAAAVGVATVFAAPFSGVLFSIEVMSSHFSVWNYWRGFFAATCGAFMFRLLAVFNSEQETITSIYKTRFRVDVPFDLPEIFFFVALGFICGILSCVYLFCQRNFLRFIKTNRYTSKLLATSKPSYAALVALVLASVTYPPGVGRFMASRLSMAEHLHSLFDNNSWALMTRNASPPWPSEPDPQNLWFEWYHPRFTIFGTLAFFLIMKFWMLILATTIPMPAGYFMPIFIIGAAIGRLLGEALSVAFPEGIVAGGEVYPIMPGGYALAGAAAFSGAVTHTISTALLAFELTGQIVHALPVLMAVLAANVISQNLQPSFYDGTIMAKKLPYLPWIRGRQIGSYPVTVEHFMNSNLTTLAKDMPLEEVVKVVTS-TDVSQYPLVETRESQTLVGIVERTHLVQALQTQPA----------------------------------------------------------------------SWAP--------------------GQE-----------------------------------------------------------------------------------------------------------------------------------------------RFLQDILAGGCPT--------------------------------------------------------------------------QPVTLQLSPETSLYQAHRLFELLTLQALFVTSRGRAVGSVSWVELKKAISTLIN----PPAPK----------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9VGH7-1", "uniprot_id": "CLCN2_DROME", "id": "Q9VGH7-1", "name": "Chloride channel protein 2", "aln": "MVYFGDRQRDRNRDRSNQKVERIIHDEEFGEENVELVDSEWADFEKFICQLRKRRNSAMSMEEELRHVQRHPKIKSHAFYPCPPPAENARDSDSSDDDDPIGYIDTLMYGRYTKDLGEFAKDEARKLKILEKRRKQEDKQRNKELLGKHSTRAKRVSSWIWRHTVARLGEDWVFLALLGIIMALLSFIMDKGISICTNARIWLYRDLTSQPFVQYIAWVSLPVCLILFSAGFVHLIAPQSIGSGIPEMKTILRGVQLKEYLTFKTLVAKVIGLTATLGSG--MPLGKEGPFVHIASIVAQLLSKLVTSFQGIYENESRNSEMLAAACAVGVGACFAAPVGGVLFSIEVTTTYFAVRNYWRGFFAAVCGATVFRLLAVWFQNADTVRALFLTNFTTEFPFDPQELFVFALIGLVCGLGGASYVWVHRRYVLFMRSNKRMNKFLQKNRFLYPGFLALLVSSISFPLGTGQFLAGELSTHEQVTQLFSNFTWSRDD--------LTVEQAAVVTHWMTSYTSVFGNLVIYTLFTFVVSIIASTIPVPSGMFIPVFKIGAGFGRLVGEFMAVTFPHGVRYGGRLSPIMPGGYAVVGAAAFSGSVTHTVSVAVIIFEMTGQITHVVPVMIAVLVANAVAALLQPSIYDSIILIKKLPYLPDLLPSSSGMYSIFVEDFMVRDVKYIWHGISYQKLKEVLKLNKTLRSLPLVDSPDNMILLGSVQRYELIKMIEKHIGREKRMEVAQKWQKEAQERALEEEKKKQEVELKMRRPSRFEVLPAPDILSLRQIANDEMLPPKKRAETMHGSLAPRKSILKKTNSFNLKTYAQPMGHSPSITPYTTITGNSEFRIRSAFEAIFKKSTTLQDVQPDPETGSLSPAASNHEVEVPRTPSTPGVSKKVQLPAQSNWDFVTDQIMLQVNPISTESNKMPAEKDFTDKALSNNGDSSKQSPSIKFKANKVADVNRSPQTAKRCSKIRFANEVGVNGSPTRTKCKIKPENVLGYSIEDVDETTNPESLAESIQKPKSVRLPRERVIDMSPEDQKQWELEEMLKPIDLQKANVHIDPSPFQLVERTSILKVHSLFSMVGINHAYVTKIGRLVGVVGLKELRKAIEDINSNSFVPPTRDEDADEKPAVEKPLLSTNSSDKAVDMTVTSMDSALSNSENCSDIEMEHIKHTDKGTVSLTMPPQESKQSPSADKSNTENGNHA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*::: . ...::::* *** . : . *: *::: : * *** ** **::***:* *: .: ..*: ****:: . :::*::*. **.*: **:** : *:* * ***:**:**:* ** *::** :*.: ***:**:.**. * : *** *****:: ::: *.:: :. * *.:::: *** **.****.: ****..******** :::*:* :********.*** :****.*: .: :*: ::: * * .:.*** *:*.*. :* :**: .. *:: :* :. *::.*: .::* ..: *..: :*:::*:::* ..*:*:*..** ::: .**.* :*: : : .* . ::**.*.:: ::.* : *:*:***:*:* *:*:* **.:***.** ::. **.*: * ********:.*******:****:*.*:: **:****.*.:**::***.**.:: ***:**. :: ******* : . * : : **.** .:. : :. . ::: :*:. . : . ***:: :. *:* *.* .*:: :: . * ** *:. : ::: . *.** :* .: * .*:: :.: **. : :: :**. *: ** *. *::***. : . **: . ", "identical_positions": 250, "similar_positions": 255, "identity": "20.78%" }, { "cls_id": "homologset.agr.MGI:1329027", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WU65-1", "uniprot_id": "GLPK2_MOUSE", "id": "Q9WU65-1", "name": "Glycerol kinase 2", "aln": "-----------------------MAASKQTSAGP-------------LVGAVVQGTNSTRFLVFNSKTAELVCSHQVELTQ-----------------------------------------------------------------EYPKEGWVEQDPKEILKSVYECIAKACEKLAEV-------NIDISNIKAIGVSNQRETTVVWDKFTGDPLYN-AVVWLDLRTQSTVETLTKKIPG---NSNFVKSKTGLP-LSTYFSAVKLRWMLDNLRPIQKAVEEGRAMFGTIDSWLIWCMTGGVNGGIHCTDVTNACRTMLFNIHSLEWDKDLCDFFEIPMSIL--PNVCSSSEIYG-------LMTS------GALEG-----VPISGCLGDQSAALVGQMCFHEGQAKNTYGTGCFLLCNTGQKCVFSEHGLLTTLAYKL------GKNKP----VFYALEGSVAIAGAVIRWLRDNFEIITTSGEVENLAREVGTSYGCYFVPAFSGLYAPYWEPSARGIICGLTQFTNKCHIAFAALEAVCFQTREILDAMNRDCG--------------------IPLSHLQVDGGMTNNRILMQLQADILH--IPVVKSVMPETTALGAAMAAGAAEG--------VNVWSLEPED--LSTILMERYEPQIQ-----------ATESEIRFSTWKRAVMKSMGWVTA--KDPENG--DNPVFSCLPLGFFIVSSMTLLIGARCVSTAEE-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F7FNM6-1", "uniprot_id": "F7FNM6_RAT", "id": "F7FNM6-1", "name": "glycerol kinase", "aln": "-----------------------MADSKETPEEP-------------LVGAVVQGTNSTRFLVFNPKTAELVGSHQVELTQ-----------------------------------------------------------------EYPKEGWVEEDPKEILQSVYECIAKTCEKLTEA-------NIDTSKIKAIGVSNQRETTVVWDKFTGEPLYN-AVVWLDLRTQSTVESLNKKIPG---NSNFVKSKTGLP-LSTYFSAVKLRWMLDNLRPIQKAVEEDRALFGTIDSWLIWCMTGGVNGGIHCTDVTNASRTMLFNIHSLEWDKELCKFFEIPMSIL--PNVRSSSEIYG-------QMTS------GALEG-----VPISGCLGDQSAALVGQMCFQEGQAKNTYGTGCFLLCNTGQKCVFSEHGLLTTVAYKL------GKNKP----AFYALEGSVAIAGAVIRWLRDNFELITSSGEVEDLAREVGTAYGCYFVPAFSGLYAPYWEPSARGIICGLTQFTNKCHIAFAALEAVCFQTREIVDAMNRDCG--------------------IPLSHLRVDGRMTNNKILMQLQADILH--IPVVKSVMPETTALGAAMAAGAAEG--------IDVWSIEPED--LSSMLMERYEPQIQ-----------ATESEIRFSTWKRAVMKSMGWVTA--KDPESN--ANPVFACLPLGFFIVFLRHLPP-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q14410-1", "uniprot_id": "GLPK2_HUMAN", "id": "Q14410-1", "name": "Glycerol kinase 2", "aln": "-----------------------MAAPKTAAVGP-------------LVGAVVQGTNSTRFLVFNSKTAELLSHHKVELTQ-----------------------------------------------------------------EFPKEGWVEQDPKEILQSVYECIARTCEKLDEL-------NIDISNIKAVGVSNQRETTVIWDKLTGEPLYN-AVVWLDLRTQTTVEDLSKKIPG---NSNFVKSKTGLP-LSTYFSAVKLRWMLDNVRNVQKAVEEGRALFGTIDSWLIWSLTGGVNGGVHCTDVTNASRTMLFNIHSLEWDKELCDFFEIPMDLL--PNVFSSSEIYG-------LIKT------GALEG-----VPISGCLGDQCAALVGQMCFQEGQAKNTYGTGCFLLCNTGRKCVFSEHGLLTTVAYKL------GREKP----AYYALEGSVAIAGAVIRWLRDNLGIIETSGDIERLAKEVGTSYGCYFVPAFSGLYAPYWEPSARGILCGLTQFTNKCHIAFAALEAVCFQTREILEAMNRDCG--------------------IPLRHLQVDGGMTNNKVLMQLQADILH--IPVIKPFMPETTALGAAMAAGAAEG--------VSVWSLEPQA--LSVLRMERFEPQIQ-----------ATESEIRYATWKKAVMKSMGWVTS--QSPEGG--DPSIFSSLPLGFFIVSSMVMLIGARYISGVP--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58J5W5-1", "uniprot_id": "A0AC58J5W5_DANRE", "id": "A0AC58J5W5-1", "name": "glycerol kinase", "aln": "----------------MNDTMPMAASSNRIMLGP-------------LVAAIDQGTSSTRFLVFNAKTAELLSHHQVEIKQ-----------------------------------------------------------------SFPKEGWVEEDPKEILQSVYECMDRTCEKLTQL-------NIDVSNIKAVGVTNQRETTLVWDKQTGEPLYN-AIVWLDLRTQSTVERLINKTPGK--NKNHLKDKTGLP-ISTYFSAVKLRWLMDNVEKVHEAVLSHRAMFGTVDSWLIWCLTGGKNGGVHCTDVTNASRTMLFNIHTMDWDPELCIYFDIPMGIL--PKVRSSSEIYG-------LMKISSKLKSGPLTG-----VPISGCLGDQSAALVGQMCFKDGQAKNTYGTGCFLLKNVGTKPVMSDHGLLTTVAYKL------GRDKP----ACYALEGSVAIAGAVVRWLKDNLGIIQTSTELEKLAADVGTSYGCYFVPAFSGLYAPYWEPSARGIICGLTQFTNRSHLAFAALEAVCFQTREILDAMNQDSG--------------------INLSQLQVDGGMTSNRLLMQLQADILC--IPVVKPSMPETTALGAAMAAGAAEG--------VSVWSLNPED--LTEVTSEKFEPQINP----------EAESELRYARWKKAVQRAMNWETI--EPVNSGNEDTSIFSSVPLGFYILGSMFMLIGAKYIAGQKLA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W095-1", "uniprot_id": "Q9W095_DROME", "id": "Q9W095-1", "name": "glycerol kinase", "aln": "----------------MTEGKNLPHSSADVPFRSKELRKQSLIQHTGLVGVIDEGTKTIGFSIYTTPDFKEIAAHRVELSV-----------------------------------------------------------------ITPQDGWYEQDPLEMMASINKCAEEAIKQLPEQ-------GFSASDIVTVGITNQRETTIVWDAVTGKPLYN-ALLWKDIRTSTTVEQIVAKVQD----PNHFRSSTGLP-ISTYFSALKIRWLRDNVPEVRQAIRERRCKAGTVDSWIVWNLT---NGALHITDVTNASRTLLMNLETQAWDPVLLKTFGIREEML--PTIHSCSEIFG-------KITS----ERSPLRG-----MTLSGIMGNQQASLLGQMCVKPGQTKNTYRSGCFLLCNTGDKPVFSRHGLLTTVAYKL------GPQAP----TIYAIEGAVSVAGHALSWLQNKVRILPDSRDAEKYAEMVPTSGDVYFVPAFTGLYAPYWRQNARGIIIGLTQFTRKNHIVRAALESICFQTRDILECMHQECG--------------------YEINKLHADGKLTTNNLLMQLQADTIG--MPVFRSQLMDSTAFGAAMCAAQADG--------VNLCQFEPEKRYYENVHYDTFLATTT-----------DVERKERYGKWKRAVERSLGWVIKQKKTREYTEENYRMLSSLPASIFLISSFAMLVHSLAASGQ---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W0U0-1", "uniprot_id": "Q9W0U0_DROME", "id": "Q9W0U0-1", "name": "glycerol kinase", "aln": "----------------MDSPTTETTPPPPTLSGP-------------FVGAIDEGTTSARFIIFRAGTDEIVCFHQIEVES-----------------------------------------------------------------IFQKEGWCEQDPMAIVNTVNECITGACKKLVAV-------GGKVEEIITIGITNQRESTVVWDRNSGQPLVN-AIIWLDNRTTSTVEELLETIPNNARNINYLRPLCGLP-LSPYFSGVKLRWLRDNVPVVSQAMEKGTAMFGTIDTWLMYNLTGGKDCGVHKTDVTNASRTMLMNIETLQWDANLLKFFGLPKTIL--PEICSSSEFYG-------SIAQ------GVLQG-----IGITSVLGDQQAALVGQQCLAKGQAKATYGTGCFLLYNTGPSIVHSTHGLLTTVGYQL------GRKAV----PFYALEGSVSIAGAAFNWLRDNMNLIQNSGQIETMASTVDNSLDVYFVPAFNGLYAPYWNQDARGVICGLSEETTSEHIVRATLEAVCFQVRDILDSMHKDCK--------------------IPLAKLMVDGGMTVNNLFLQLQSDLVG--IQVLRAKIAETTALGAAMAAYKAVE--------NRYQMEAPLS---KSGPREAIKPSIS-----------ATDRNLRYQKWKMAIDRSLNWETS----------------TLPQGEREAFDGA--------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32190-1", "uniprot_id": "GLPK_YEAST", "id": "P32190-1", "name": "Glycerol kinase", "aln": "MFPSLFRLVVFSKRYIFRSSQRLYTSLKQEQSRMSKIMEDLRSDYVPLIASIDVGTTSSRCILFN-RWGQDVSKHQIEYSTSASKGKIGVSGLRRPSTAPARETPNAGDIKTSGKPIFSAEGYAIQETKFLKIEELDLDFHNEPTLKFPKPGWVECHPQKLLVNVVQCLASSLLSLQTINSERVANGLPPYKVICMGIANMRETTILWSRRTGKPIVNYGIVWNDTRTIKIVRDKWQNTSVD--RQLQLRQKTGLPLLSTYFSCSKLRWFLDNEPLCTKAYEENDLMFGTVDTWLIYQLT---KQKAFVSDVTNASRTGFMNLSTLKYDNELLEFWGIDKNLIHMPEIVSSSQYYGDFGIPDWIMEKLHDSPKTVLRDLVKRNLPIQGCLGDQSASMVGQLAYKPGAAKCTYGTGCFLLYNTGTKKLISQHGALTTLAFWFPHLQEYGGQKPELSKPHFALEGSVAVAGAVVQWLRDNLRLIDKSEDVGPIASTVPDSGGVVFVPAFSGLFAPYWDPDARATIMGMSQFTTASHIARAAVEGVCFQARAILKAMSSDAFGEGSKDRDFLEEISDVTYEKSPLSVLAVDGGMSRSNEVMQIQADILGPCVKVRRSPTAECTALGAAIAANMAFKDVNERPLWKDLHDVKKWVFYNGMEKNEQISPEAHPNLKIFRSESDDAERRKHWKYWEVAVERSKGWLKD-----------------IEGEHEQVLENFQ-------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::. : **.: :: : : *::* : ** * .* :: .: :* : .* . .: :*::* **:*::*. :*.*: * .::* * ** . *. . .: *** :*.*** *:**: ** :* . **:*:*::: :* . . :*****.** ::*: : :* * : : :: * : *.*: :* : * . : : . :*:* *:::** . * :* ** :***** *.* . : * ** ***:.: : * . :*:**:*::** .. **:::. :: * : * * : . *****.**:**** .**. : *::: * *:. *::*.:***.* *:..* :. : * .** :: .. .:*:*:* : : * :. : **:***:.* * : . .: . :: *: *: :: .* : ", "identical_positions": 132, "similar_positions": 159, "identity": "17.72%" }, { "cls_id": "homologset.agr.MGI:1329031", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97884-1", "uniprot_id": "CCL20_RAT", "id": "P97884-1", "name": "C-C motif chemokine 20", "aln": "MAC--KHLPFLALAGVLLAYLCSQSEAASNFDCCLTYTKNVYHHARNFVGFTTQMADEACDINAIIFHLKSKRSVCADPKQIWVKRILHLLSLRTKKM-------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O89093-1", "uniprot_id": "CCL20_MOUSE", "id": "O89093-1", "name": "C-C motif chemokine 20", "aln": "MACGGKRLLFLALAWVLLAHLCSQAEAASNYDCCLSYIQTPLP-SRAIVGFTRQMADEACDINAIIFHTKKRKSVCADPKQNWVKRAVNLLSLRVKKM-------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P78556-1", "uniprot_id": "CCL20_HUMAN", "id": "P78556-1", "name": "C-C motif chemokine 20", "aln": "MCCT-KSLLLAALMSVLLLHLCGESEAASNFDCCLGYTDRILH-PKFIVGFTRQLANEGCDINAIIFHTKKKLSVCANPKQTWVKYIVRLLSKKVKNM-------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BIN2-1", "uniprot_id": "A0A8M2BIN2_DANRE", "id": "A0A8M2BIN2-1", "name": "", "aln": "MSL--VSITLISIVFLSLLPHTPKAYGPLNYACCVKYTRTPLP-FGVIAGFIEQSSLEVCRIDAIIFITQKNKKICASIEDQWVRAALAHLRSKIAKLENKASLRLTTAGPNSVIQTNTTNSP", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. : : :: : * :: .. *: **: * :.** * : * * *:**** :.. .:**. :: **: : * : :: ", "identical_positions": 21, "similar_positions": 29, "identity": "17.07%" }, { "cls_id": "homologset.agr.MGI:1329033", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P09139-1", "uniprot_id": "AGT1_RAT", "id": "P09139-1", "name": "Alanine--glyoxylate aminotransferase", "aln": "MFRMLAKASVTLGSRAASWVRNMGSHQLLVPPPEALSKPLSIPKRLLLGPGPSNLAPRVLAAGSLRMIGHMQKEMFQIMDEIKQGIQYVFQTRNP---LTLVVSGSGHCAMETALFNLLE---PGDSFLVGTNGIWGIRAAEIAERIGARVHQMIK-KPGEHYTLQEVEEGLAQHKPVLLFLTHGESSTGVLQP-LDGFGELCHRY--QCLLLVDSVASLGGVPIYMDQQGIDILYSGSQKVLNAPPGISLISFNDKAKSKVY--SRKTKPVSFYTDITYLSKLWGCEGKTR-VIHHTLPVISLYCLRESLALISEQGLENSWRRHREATAHLHKCLRELGLKFFVKDPEIRLPTITTVTVPAGYNWRDIVSYVLDHFNIEISGGLGPSED-KVLRIGLLGYNATTENADRVAEALREALQHCPK------NKL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35423-1", "uniprot_id": "AGT1_MOUSE", "id": "O35423-1", "name": "Alanine--glyoxylate aminotransferase", "aln": "MFRMLAKASVTLGSRAAGWVRTMGSYQLLVPPPEALSKPLSVPTRLLLGPGPSNLAPRVLAAGSLRMIGHMQKEMLQIMEEIKQGIQYVFQTRNP---LTLVVSGSGHCAMETALFNLLE---PGDSFLTGTNGIWGMRAAEIADRIGARVHQMIK-KPGEHYTLQEVEEGLAQHKPVLLFLVHGESSTGVVQP-LDGFGELCHRY--QCLLLVDSVASLGGVPIYMDQQGIDIMYSSSQKVLNAPPGISLISFNDKAKYKVY--SRKTKPVSFYTDITYLAKLWGCEGETR-VIHHTTPVTSLYCLRESLALIAEQGLENCWRRHREATAHLHKHLQEMGLKFFVKDPEIRLPTITTVTVPAGYNWRDIVSYVLDHFSIEISGGLGPTEE-RVLRIGLLGYNATTENVDRVAEALREALQHCPK------NKL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P21549-1", "uniprot_id": "AGT1_HUMAN", "id": "P21549-1", "name": "Alanine--glyoxylate aminotransferase", "aln": "----------------------MASHKLLVTPPKALLKPLSIPNQLLLGPGPSNLPPRIMAAGGLQMIGSMSKDMYQIMDEIKEGIQYVFQTRNP---LTLVISGSGHCALEAALVNVLE---PGDSFLVGANGIWGQRAVDIGERIGARVHPMTK-DPGGHYTLQEVEEGLAQHKPVLLFLTHGESSTGVLQP-LDGFGELCHRY--KCLLLVDSVASLGGTPLYMDRQGIDILYSGSQKALNAPPGTSLISFSDKAKKKMY--SRKTKPFSFYLDIKWLANFWGCDDQPR-MYHHTIPVISLYSLRESLALIAEQGLENSWRQHREAAAYLHGRLQALGLQLFVKDPALRLPTVTTVAVPAGYDWRDIVSYVIDHFDIEIMGGLGPSTG-KVLRIGLLGCNATRENVDRVTEALRAALQHCPK------KKL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W3Z3-1", "uniprot_id": "AGT_DROME", "id": "Q9W3Z3-1", "name": "Alanine--glyoxylate aminotransferase", "aln": "---------------------------MEVPPPLVLKRPLYVPSKTLMGPGPSNCSHRVLEAMSNPVLGHMHPECLQIMDEVKEGIKYIFQTLND---ATMCISGAGHSGMEAALCNLIE---DGDVVLMGITGVWGHRAGDMARRYGAEVHYVEA-SFGRALSHEEITFAFEAHRPKVFFIAQGDSSTGIIQQNIRELGELCRKY--DCFLIVDTVASLGGTEFLMDEWKVDVAYTGSQKSLGGPAGLTPISFSKRALTRIR--KRKTKPKVYYFDILLIGQYWGCYGTPR-IYHHTISSTLLYGLREALAHFCAVGLKAVVRRHQECSKRLQLGIEELGLEMFVSREEERLPTVNTIKVPFGVDWKKVAEYAMRKYSVEISGGLGPTVE-HVFRIGLMGENATVERVDMVLSILNEAIQSSKLGIKTDLSKI", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P43567-1", "uniprot_id": "AGX1_YEAST", "id": "P43567-1", "name": "Alanine--glyoxylate aminotransferase 1", "aln": "---------------------------------------MTKSVDTLLIPGPIILSGAVQKALDVPSLGHTSPEFVSIFQRVLKNTRAVFKSAAASKSQPFVLAGSGTLGWDIFASNFILSKAPNKNVLVVSTGTFSDRFADCLRSYGAQVDVVRPLKIGESVPLELITEKLSQNSYGAVTVTHVDTSTAVLSD-LKAISQAIKQTSPETFFVVDAVCSIGCEEFEFDEWGVDFALTASQKAIGAPAGLSISLCSSRFMDYALNDSKNGHVHGYFSSLRRWTPIMENYEAGKGAYFATPPVQLINSLDVALKEILEEGLHKRWDLHREMSDWFKDSLVN-GLQLTSVSRYPSNMSAHGLTAVYVADPPDVIAFLKSHG-VVIAGGIHKDIGPKYIRIGHMGVTACNKNLPYMKNCFDLIKLALQR------KK-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . *: *** . : * . :* : .*::.: :. : :*:: .: ::*:* . : *.: .. .* .* :. * : **.*. : . * . : : : : . :.: ::**.::. : :.: :: . :::**:*.*:* : :*. :*. :.*** :..*.* : ..: .:: : :: .: : . * . : * :* : **. *:* : :: : **:: : : . : .: : : : * **: : :*** :* .* :. : . : .* ", "identical_positions": 50, "similar_positions": 124, "identity": "11.52%" }, { "cls_id": "homologset.agr.MGI:1329034", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZQ41-1", "uniprot_id": "D3ZQ41_RAT", "id": "D3ZQ41-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSRRSS---RLQAKQQHARPNQPDSP-------QEAQIIQ---AKKRKTAQDVKKRTEE------ITKKHQYEIRN------------CWPPVLSGGISPCIIIETP--HKEIGTSDFSRFTNYRFKNLFINP--------------SPLPDLSWACSQEVWQNMLQKESR--YVHDKHFEVLHSDLEPQMRSILLDWLLEVCEVYTLHRETFYLAQDFFDRFMLTQKDVNKNMLQLIGITSLFIASKLEEIYAPKLQEFAYVTDGACSEVDILKMELNILKALKWELCPVTVISWLNLFLQVDAVKDIPK----------------VLLPQYSQETFIQIAQLLDLCILAIDSLEFQYRILAAAALCHFTSIEVVKKASGLEWDDISECVDWMVPFVSVVKSVSP-VKLKT--------------FKKIPMEDRHNIQTHTNYLALLNEVNYVN----IFRKGGQLSPVCNG----GIMTPPKSTEKPPVKF----------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z238-1", "uniprot_id": "CCNE2_MOUSE", "id": "Q9Z238-1", "name": "G1/S-specific cyclin-E2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSRRSS---RLQAK-QHAQPNQPDSP-------QETQIIQ---AKKRKTAQDVKKRKEE------ITKKHQYEIRN------------CWPPVLSGGISPCIIIETP--HKEIGTSDFSRFTNYRFKNLFINP--------------SPLPDLSWACSQEVWQNMLQKENR--YVHDKHFQVLHSDLEPQMRSILLDWLLEVCEVYTLHRETFYLAQDFFDRFMLTQKDVNKNMLQLIGITSLFIASKLEEIYAPKLQEFAYVTDGACSEVDILKMELNILKALKWELCPVTVISWLNLFLQVDAVKDVPK----------------VLLPQYSQETFIQIAQLLDLCILAIDSLEFQYRILAAAALCHFTSIEVVKKASGLEWDDISECVDWMVPFVSVVKSVSP-VKLKT--------------FKKIPMEDRHNIQTHTNYLALLNEVNYVN----IYRKGGQLSPVCNG----GIMTPPKSTEKPPGKH----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O96020-1", "uniprot_id": "CCNE2_HUMAN", "id": "O96020-1", "name": "G1/S-specific cyclin-E2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSRRSS---RLQAK-QQPQPSQTESP-------QEAQIIQ---AKKRKTTQDVKKRREE------VTKKHQYEIRN------------CWPPVLSGGISPCIIIETP--HKEIGTSDFSRFTNYRFKNLFINP--------------SPLPDLSWGCSKEVWLNMLKKESR--YVHDKHFEVLHSDLEPQMRSILLDWLLEVCEVYTLHRETFYLAQDFFDRFMLTQKDINKNMLQLIGITSLFIASKLEEIYAPKLQEFAYVTDGACSEEDILRMELIILKALKWELCPVTIISWLNLFLQVDALKDAPK----------------VLLPQYSQETFIQIAQLLDLCILAIDSLEFQYRILTAAALCHFTSIEVVKKASGLEWDSISECVDWMVPFVNVVKSTSP-VKLKT--------------FKKIPMEDRHNIQTHTNYLAMLEEVNYIN----TFRKGGQLSPVCNG----GIMTPPKSTEKPPGKH----------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P54733-1", "uniprot_id": "CCNE_DROME", "id": "P54733-1", "name": "G1/S-specific cyclin-E", "aln": "MGLNAKSVCSTSSTEPNGSIVTTAPSNGEVSSSIVVVVSSSSISSSSDSPIAILPHPDPIPSTSFSSASQRSEEELPGTSAASRTDEMCSCDSQNLAASTAATSNGNKRKRRLSSDSNEDPELGFEPPSAKRQQRLPALYGSEQGNLSSVASSVYTSPVVSVDGQSTQELLSIRSSPAEDLSEAPHSPLPDSPDSPPSPDRGSKQTPVVVRYAAEQVVTSTVVTQKTEDDDLLDDSCEDYSYDEDDEDDVEEEDDDVEIYSSTISPASSGCSQQQAVNGERTPGLPKHQEQIHHPVSDLMINMRTPMSPAVENGLRQCPLPALAWANAADVWRLMCHRDEQDSRLRSISMLEQHPGLQPRMRAILLDWLIEVCEVYKLHRETFYLAVDYLDRYLHVAHKVQKTHLQLIGITCLFVAAKVEEIYPPKIGEFAYVTDGACTERDILNHEKILLQALDWDISPITITGWLGVYMQLNVNNRTPASFSQIGRQKSAEADDAFIYPQFSGFEFVQTSQLLDLCTLDVGMANYSYSVLAAAAISHTFSREMALRCSGLDWQVIQPCARWMEPFFRVISQKAPYLQLNEQNEQVSNKFGLGLICPNIVTDDSHIIQTHTTTMDMYDEVLMAQDAAHAMRARIQASPATALRAPESLLTPPASSHKPDEYLGDEGDETGARSGISSTTTCCNTAASNKGGKSSSNNSVTSCSSRSNP", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* *** *. : . *...:** ::: :: *:: *: *.:: *: :.:.*: : :...:* . * * :: .: * ..... :: ..:*:** .*** *:*. : :** * :::.: ::. : *..*:*:**:******:******.********* *::**:: . :.::*. *******.**:*:*:****.**: **********:* ***. * :*:**.*::.*:*: .**.:::*::. : * .: **:* *:* :****** * :. ::.* :*:***:.* * *:. :.***:*: *. *. ** **. *:.. :* ::*: :* :* * *****. : : :** : * * **. .::*** *:.** ", "identical_positions": 153, "similar_positions": 146, "identity": "21.58%" }, { "cls_id": "homologset.agr.MGI:1329035", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62867-1", "uniprot_id": "GGH_RAT", "id": "Q62867-1", "name": "Gamma-glutamyl hydrolase", "aln": "MASLGRLLCAWVLLLCGLASPGLSGSYERGSKRPIIGIIMQECYGNMTK-----LGRFYIAASYVKFIESAGARVVPIRLDLNDAQYETLFRSINGVLLPGGGANLTHS----------GYSRVAKIFFTKALES-------FDNGDYFPVWGTCLGLEELSVLVSNDNLLTLTNTSS-VKLPLNFTRDSKQSRMFRNLPEELLNSLASENLTANFHKWSLSVKNFTENEKLKKFFNILTVNTDG-KTEFISSMEGYKYPIYAVQWHPEKAPFEWKKLRG----ISHAPNAVKTSFYLAKFFISEALKNDHHFENELEETESLIYQFCPVYTGNISS--FQQAYMFN---------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z0L8-1", "uniprot_id": "GGH_MOUSE", "id": "Q9Z0L8-1", "name": "Gamma-glutamyl hydrolase", "aln": "MANLGYLLCLLGLLLCGLSSPGMSRPYNHGSERPIIGVVMQECFGKMAK-----LGNYYIAASYVKYIESAGARVVPIRPDLSDAEYEELFRSINGVLLPGGGANLTDS----------GYSRVAKIFFSKALES-------FDNGDHFPVWGTCLGFEELSVLVSGENLLTSTDTKS-KKLPLNFTEGARKSRMFKHFPTELLDSLALENLTANFHKWSLSVKNFTENEKLKKFFNILTTNTDG-KTEFISSMEGFKYPVYAVQWHPEKAAFEWKNLGG----ISHAPNAVKTSFYLAEFLVSEARKNSHHFENVVKETASLIYKFNPIYTGNISS--FQQAYMFD---------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92820-1", "uniprot_id": "GGH_HUMAN", "id": "Q92820-1", "name": "Gamma-glutamyl hydrolase", "aln": "MASPGCLLCVLGLLLCGAASLELSRPHGDTAKKPIIGILMQKCRNKVMKN----YGRYYIAASYVKYLESAGARVVPVRLDLTEKDYEILFKSINGILFPGGSVDLRRS----------DYAKVAKIFYNLSIQS-------FDDGDYFPVWGTCLGFEELSLLISGECLLTATDTVD-VAMPLNFTGGQLHSRMFQNFPTELLLSLAVEPLTANFHKWSLSVKNFTMNEKLKKFFNVLTTNTDG-KIEFISTMEGYKYPVYGVQWHPEKAPYEWKNLDG----ISHAPNAVKTAFYLAEFFVNEARKNNHHFKSESEEEKALIYQFSPIYTGNISS--FQQCYIFD---------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8IQM9-1", "uniprot_id": "Q8IQM9_DROME", "id": "Q8IQM9-1", "name": "folate gamma-glutamyl hydrolase", "aln": "MQKFSISLLIFIGALLAASEAGIS--------SPIIGVLTQEVYVDGLISRHFDNKTSYIAASYVKYLEGAGARVVPIWIGRNRSYYDDLMRKINGVLLPGGATWFNQSN---------GYADAGEHLIHLAIEL-------NDQGVFMPVWGTCLGMELLVYKLANETEHRINCEATGMAVPMEFKEDYKKSRLFASITDDVVDTMVKENVTYHWHQFCYTEKDFER-DLLNETWRVMSLNHDWNGVEFISTVEHIKYPFYGVQFHPEKPLYEFTKTS-----IPHTAAAVLSGQFFADFFVSEARESNQSFSNATEQARTLIYNYKPEYTSILGSS-YIQQYLFTNVEMEIPEIPEIPDEGGNNDGGSSGGYIPIVVPGGDGSTTMPLLSGLLLTLVLLSIN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VV00-1", "uniprot_id": "Q9VV00_DROME", "id": "Q9VV00-1", "name": "folate gamma-glutamyl hydrolase", "aln": "MAESAYTDAPYLNRVPTVGVMCID-----------IATQLQQNFSGAYHS--------YLAASYVKFLEASGAHVVPIWIGRERAYYALMMSQLNGILLPGGAVFIDEADRQANPDVTSDCVRSAELIYQLAMERNMRAKKLDDRGAYFPVWGTCLGFQLILIHAAEAPNVRIACQPMREAMPVTLTDDYQQSQLLGSLPKSVADEMEKHPFACHQHRYCITKESLES-YGLAKDWHPLATQKDTSGLEFITIVEHRRFPIFGCQFHPERAAFEQLFNSPDKCYMAHSRMGIDLSQIFGSRFVDFCRRNNNQFESDKLKTRHLIWNWQPVFSGKFKGSNWQQCYLFEKNVDYSEEPDDSEELRSS---------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . . : . :. *. *: *:******::*.:**:***: . * :: .:**:*:***.. : : . .: : ::: * * .:********:: : : :*: :. . :*::: :. .: : . .: : *::. : :.: * : :. :: : * ***: :* ::*.:. *:***:. :* :.*: .: . :.. ::. . ...: *.. : **::: * ::. : . : * *:* ", "identical_positions": 56, "similar_positions": 111, "identity": "13.86%" }, { "cls_id": "homologset.agr.MGI:1329037", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XIG8-1", "uniprot_id": "STRAP_RAT", "id": "Q5XIG8-1", "name": "Serine-threonine kinase receptor-associated protein", "aln": "---MAMRQTPLTCSGHTRPVVDLAFSGITPYGYFLISACKDGKPMLRQGDTGDWIGTFLGHKGAVWGATLNKDATKAATAAADFTAKVWDAVSGDELMTLAHKHIVKTVDFTQDSNYLLTGGQDKLLRIYDLNKPEAEPKEISGHTSGIKKALWCSEDKQILS-ADDKTVRLWDHATMTEVKSLNFNMSVSSMEYIPEGEILVITYGRSIAFHSAVSLEPIKSFEAPATINSASLHPEKEFLVAGGEDFKLYKYDYNSGEELESYKGHFGPIHCVRFSPDGELYASGSEDGTLRLWQTVVGKTYGLWKCVLPEEDSGELAKPKIGFPETAEEELEEIASENSDSIYSSTPEVKA-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z1Z2-1", "uniprot_id": "STRAP_MOUSE", "id": "Q9Z1Z2-1", "name": "Serine-threonine kinase receptor-associated protein", "aln": "---MAMRQTPLTCSGHTRPVVDLAFSGITPYGYFLISACKDGKPMLRQGDTGDWIGTFLGHKGAVWGATLNKDATKAATAAADFTAKVWDAVSGDELMTLAHKHIVKTVDFTQDSNYLLTGGQDKLLRIYDLNKPEAEPKEISGHTSGIKKALWCSDDKQILS-ADDKTVRLWDHATMTEVKSLNFNMSVSSMEYIPEGEILVITYGRSIAFHSAVSLEPIKSFEAPATINSASLHPEKEFLVAGGEDFKLYKYDYNSGEELESYKGHFGPIHCVRFSPDGELYASGSEDGTLRLWQTVVGKTYGLWKCVLPEEDSGELAKPKIGFPETAEEELEEIASENSDSIYSSTPEVKA-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y3F4-1", "uniprot_id": "STRAP_HUMAN", "id": "Q9Y3F4-1", "name": "Serine-threonine kinase receptor-associated protein", "aln": "---MAMRQTPLTCSGHTRPVVDLAFSGITPYGYFLISACKDGKPMLRQGDTGDWIGTFLGHKGAVWGATLNKDATKAATAAADFTAKVWDAVSGDELMTLAHKHIVKTVDFTQDSNYLLTGGQDKLLRIYDLNKPEAEPKEISGHTSGIKKALWCSEDKQILS-ADDKTVRLWDHATMTEVKSLNFNMSVSSMEYIPEGEILVITYGRSIAFHSAVSLDPIKSFEAPATINSASLHPEKEFLVAGGEDFKLYKYDYNSGEELESYKGHFGPIHCVRFSPDGELYASGSEDGTLRLWQTVVGKTYGLWKCVLPEEDSGELAKPKIGFPETTEEELEEIASENSDCIFPSAPDVKA-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W1N4-1", "uniprot_id": "Q9W1N4_DROME", "id": "Q9W1N4-1", "name": "Serine-threonine kinase receptor-associated protein", "aln": "MAANNLRQIPLTCSGHTRPVVHLDFSDICDAGYFLISACKDGSPMLRHGDTGDWVGTFEGHKGAVWNATLNRNATLAASGAADFTGKVWNAVTGAEIHSFQHKHIVKSVAFDRDSENIVTGSNEKLVRVFNLEQPEAQPEEYAGHTGAIKRALFCRGDKCIISAAEDKTVRLWDRMTGIEVQRLQFNSNPNSLEISSDNHILTISHGSSISFWEIDTLKKLKEVKVPTNVASASLHPDKHVFVCGGEDFKMYKFDYITGNEIESFKGHFGPVHSVKFSPDGELYASGSEDGTLRLWQTTVGKTYGLWKCTEP-ADLG-----------------------NS---ISSPREVQAN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :** ************.* **.* ***********.****:******:*** *******.****::** **:.*****.***:**:* *: :: ******:* * :**: ::**.::**:*:::*::***:*:* :***..**:**:* ** *:* *:********: * **: *:** . .*:* .:..**.*::* **:* . :*. :*..:.*:.: ******:*..:*.******:**:** :*:*:**:******:*.*:**********************.**********. * * * ** .*. :*:* ", "identical_positions": 199, "similar_positions": 85, "identity": "56.06%" }, { "cls_id": "homologset.agr.MGI:1329038", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZT80-1", "uniprot_id": "A0A8I5ZT80_RAT", "id": "A0A8I5ZT80-1", "name": "", "aln": "MRAPGPRGEGRPTSRPSRAPEPSGRLTPAALGSRLRSSPTSAHLGAAERCGGGESLEMVSSDRPVSLEDEVSHS-MKEMIGGCCVCSDERGWAENPLVYCDGHGCSVAVHQACYGIVQVPTGPWFCRKCESQERAAR------------------------------------------VRCELCPHKDGALKRTDNGGWAHVVCALYIPEVQFANVSTMEPIVLQSVPHDRYNKTCYICDEQGRESKAATGACMTCNKHGCRQAFHVTCAQFAGLLCEEEGNGADNVQYCGYCKYHFSKLKK--------------------------------------------------SKRGSNRSYDQSLSD------------SSSHSQDKHHEKEKKKYKEKDKHKPKHKKQPEPSPALVPS------------------------------------------------------------------------------LTVTTEKTYTSTSN----NSISGSLKRLEDTAARFTNANFQEVSAHTSSG-KD--VSEAR-SEGKGKKS----------------SAHSSGQRGRKPGGGRNPG---------TTVSASSPFPQGSFSGTPGSVKSS-SGSSVQSPQDFLSFTDS------DLRN-DSYTHTQPPPSTKDVHKGEPGSQD---AGVNSFSSLVGHPGTSGATSQPKSFDSSPGELGSSSLPTAGYKRAQTSGVEEEEAVKEKKRK-GNKQSKHGPGRPKGN--------------------------------KNQENVSHLSVSSASPTSSVASAAGSVTSCSLQKSPTLLRNGSMQSLSVGSSPLGSEISMQYRHDG---ACPTTS-----------IYNSNDVAVSFPNVVSGSGSSTPVSSS------HIPQQSSGHLQQVGALSPSAASSVTPAAATTQANT-----APGSSLSQAPAHVYGSRLNQNPSMAVLIAQSESSQTDQDLGDNTRSLVGRGSSPRGS------LSPRSPVSNLQIRYDQ----------PSS-SGLESLPPVAVSIEQLLERQWSEGQQFLLEQGTPS-------------DILGMLKSLHQLQVENRRLEEQIKNLTAKKERLQLLNAQLSVPF-PAITTNPSPSHQIHTYTAQTAPTTDSLNSSKSPHIGN-------------SFVPDNSLPVLNQDLTSSGQST-SSSSALSTPPPAGQSPAQQGSGVSGVQQVNGVTVGPLASGMQTVTSTIPAVSAVGGIIGALPGNQLAING------------------IVGALNGVIQTP-VTISQNPAPLTHTSVPPNAAHPMPAAALTN---SASGLGLLSDQQRQMFLQQQQFQQLLNSQQLTPEQHQAFLYQLMQ---QQHHPPELQQMQL---------------PGPTQIPINNLLAGPPAPPLHTATTNPFLTIHGDSTS----------------QKVTRLSDKTGPVA-QEKS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O54826-1", "uniprot_id": "AF10_MOUSE", "id": "O54826-1", "name": "Protein AF-10", "aln": "---------------------------------------------------------MVSSDRPVSLEDEVSHS-MKEMIGGCCVCSDERGWAENPLVYCDGHGCSVAVHQACYGIVQVPTGPWFCRKCESQERAAR------------------------------------------VRCELCPHKDGALKRTDNGGWAHVVCALYIPEVQFANVSTMEPIVLQSVPHDRYNKTCYICDEQGRESKAATGACMTCNKHGCRQAFHVTCAQFAGLLCEEEGNGADNVQYCGYCKYHFSKLKK--------------------------------------------------SKRGSNRSYEQSLSD------------SSSHSQDKHHEKEKKKYKEKDKHKQKHKKQPEPSPALVPS------------------------------------------------------------------------------LTVTTEKTYTSTSN----NSISGSLKRLEDTAARFTNANFQEVSAHTSSG-KD--VSEARGSEGKGKKS----------------SAHSSGQRGRKPGAGRNPG---------TAVSASSPFPQGSFSGTPGSVKSS-SGSSVQSPQDFLSFTDS------DLRS-DSYTHTQQPSSTKDVHKGESGSQE---AAVNSFSSLVGHPVTSTVISQPKSFDNSPGELGSSSLPTAGYKRAQTSGIEEE-AVKEKKRK-GNKQSKHGPGRPKGN--------------------------------KNQENVSHLSVSSASPTSSVASAAGSVTSSSLQKSPTLLRNGSLQSLSVGSSPVGSEISMQYRHDG---ACPTTTFSELLNAIHNGIYNSNDVAVSFPNVVSGSGSSTPVSSS------HIPQQSSGHLQQVGALSPSAASSVTPAAATTQANT-----VSGSSLSQAPAHMYGSRLNQNPSMAVLIAQSESSQTDQDLGDNARSLGGRGSSPRGS------LSPRSPVSNLQLRYDQ----------PSN-SSLETVPPVAASIEQLLERQWSEGQQFLLEQGTPG-------------DILGMLKSLHQLQVENRRLEEQIKNLTAKKERLQLLNAQLSVPF-PAITTNPSPSHQMHTYTAQTAPPPDSLNSSKSPHIGN-------------SFLPDNSLPVLNQDLTSSGQST-SSSSALSTPPPAGQSPAQQSSGVSGVQQVNGVTVGALASGMQTVTSTIPAVSAVGGIIGALPGNQLAING------------------IVGALNGVIQTP-VTISQNPAPLTHTSVPPNAAHPMPAAALTN---SASGLGLLSDQQRQMFIQQQQFQQLLNSQQLTPEQHQAFLYQLMQ---QQHHPPELQQLQL---------------PGPTQIPINNLLAGAQAPPLHTATTNPFLTIHGDSTS----------------QKVTRLSDKTGPVA-QEKS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P55197-4", "uniprot_id": "AF10_HUMAN", "id": "P55197-4", "name": "Protein AF-10", "aln": "---------------------------------------------------------MVSSDRPVSLEDEVSHS-MKEMIGGCCVCSDERGWAENPLVYCDGHGCSVAVHQACYGIVQVPTGPWFCRKCESQERAAR------------------------------------------VRCELCPHKDGALKRTDNGGWAHVVCALYIPEVQFANVSTMEPIVLQSVPHDRYNKTCYICDEQGRESKAATGACMTCNKHGCRQAFHVTCAQFAGLLCEEEGNGADNVQYCGYCKYHFSKLKK--------------------------------------------------SKRGSNRSYDQSLSD------------SSSHSQDKHHEKEKKKYKEKDKHKQKHKKQPEPSPALVPS------------------------------------------------------------------------------LTVTTEKTYTSTSN----NSISGSLKRLEDTTARFTNANFQEVSAHTSSG-KD--VSETRGSEGKGKKS----------------SAHSSGQRGRKPGGGRNPG---------TTVSAASPFPQGSFSGTPGSVKSS-SGSSVQSPQDFLSFTDS------DLRN-DSYSHSQQSSATKDVHKGESGSQE---GGVNSFSTLIGLPSTSAVTSQPKSFENSPGDLGNSSLPTAGYKRAQTSGIEEE-TVKEKKRK-GNKQSKHGPGRPKGN--------------------------------KNQENVSHLSVSSASPTSSVASAAGSITSSSLQKSPTLLRNGSLQSLSVGSSPVGSEISMQYRHDG---ACPTTTFSELLNAIHNGIYNSNDVAVSFPNVVSGSGSSTPVSSS------HLPQQSSGHLQQVGALSPSAVSSAAPAVATTQANT-----LSGSSLSQAPSHMYGNRS--NSSMAALIAQSENNQTDQDLGDNSRNLVGRGSSPRGS------LSPRSPVSSLQIRYDQ----------PGN-SSLENLPPVAASIEQLLERQWSEGQQFLLEQGTPS-------------DILGMLKSLHQLQVENRRLEEQIKNLTAKKERLQLLNAQLSVPF-PTITANPSPSHQIHTFSAQTAPTTDSLNSSKSPHIGN-------------SFLPDNSLPVLNQDLTSSGQST-SSSSALSTPPPAGQSPAQQGSGVSGVQQVNGVTVGALASGMQPVTSTIPAVSAVGGIIGALPGNQLAING------------------IVGALNGVMQTP-VTMSQNPTPLTHTTVPPNATHPMP-ATLTN---SASGLGLLSDQQRQILIHQQQFQQLLNSQQLTPEQHQAFLYQLMQHHHQQHHQPELQQLQI---------------PGPTQIPINNLLAGTQAPPLHTATTNPFLTIHGDNAS----------------QKVARLSDKTGPVA-QEKS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6YVP0-1", "uniprot_id": "A0A8M6YVP0_DANRE", "id": "A0A8M6YVP0-1", "name": "", "aln": "--------------------------MCAYFSQRIVSSKFDEEDSYFR------ECEMVSSELYLAEEDDDSPSNMKEMIGGCCVCSDERGWAENPLVYCDGHGCNVAVHQACYGIVQVPTGPWFCRKCESQERAARVIKGWRGRKPSWQTPEGGGQSTTCNKEEEDSRLSRSLKTLNIVRCELCPQKDGALKRTDNGGWAHVVCALYIPEVEFANVSTMEPIVLQSVPHERYNKTCYICEEQGRESKAATGACMTCNKHGCRQAFHVTCAQLAGLLCEEQGSDADNVKYCGYCKYHYNKLRR--------------------------------------------------SKGRGSR--AQSLSD------------SSTHSLDKHHDKEKKKHKERDRHKPKHKKPLELSPSLVPA------------------------------------------------------------------------------LMVTPEKSYNNSSSGGSVSSISSTQKRLDDSGARFTNANFQEVPPHSSSSSKDGGSSDGKSSDSKSKKSS-------------HSTSSSSGSRGRKSVAGKPHGPVVTTATSSTAPSSTSPFQQGHLLGSNSSSKSATSGSVVQPTSDFLSFSDP------SLRAGDSYTPPSFGRCHMKGG-AESGASESM-VALNTFSMIPLSQSSSSSSSKHYENCHTTGELG--SLASASYKRPQPSSSSSSATSSSSTGEDGVKKKKRGNWRNRYGPC-----------------------------FTTQDSKTTDAGEHISTMPSSTSPSPSSMSNMVCRGSTVSSTASVGAVGAGTSSLGIQKSPSLLRNGSLQGMTVSSPPAVPGEQKRSYPSSSDVACPLPSAVLG--GSMSASNS------ELPAHQSVVVTSMPTLTSLPSAAPFTSTPSTHANS-----LPG-SFNLAPSHMFGNRLNPNSAMAALIAQSEGSPADQELGDGALGFSRRGNSPKTN------LSPRSPLSGLHIRYDAG------PMVPGLGSGSDTLPPAATSIDQLLERQWNEGQQFLLQQGSQG-------------DVLAMLKSLHQLQVENRRLEEQIRTLTMKKERLQLLSAQLSVPFTPASTTATTASSPMYPSNTHTD-----MLHSKSIQLG--------------SVLTESSQPLPTQDPQSGGHSSGSSTSSLSTPPSAAHSPPQQ--------QVNGVGMAGVPVQPGNANSSLPAIAGVTGLMGALQGNHLAMSG------------------IVGALNGVIQTSQSSLTQNSSPLPQSATASSASLSMS-SSLTNSSMSTTKTRLFTEQHRQILLHQHQLQQLFGSQQPTPEQQQVLLYQLMQ---QQQQQQQQQQQND---------------IQFQQLPINSLLPGNQP----TTSTNPFLAHHNDNNTPKAGVNTAA------IKQTKRLGEKAVPVTGQEKT----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KGP1-1", "uniprot_id": "A0A0B4KGP1_DROME", "id": "A0A0B4KGP1-1", "name": "", "aln": "----------------------MCERNNNKQVTSSNKIPSSFNAKLELDSSKDDTIHSTSLNKKLVKIKKFKLDDMKEMVGGCCVCSDERGWPENPLVYCDGQNCTVAVHQACYGIVTVPTGPWYCRKCESQERTSR------------------------------------------VRCELCPSRDGALKKTDNSGWAHVVCALYIPEVRFGNVTTMEPIILSLIPQERYSKTCYICQEIGKPNRANVGACMQCNKSNCKQQFHVTCAQSLGLLCEEAGNYLDNVKYCGYCQHHYSKLKKGGNVKTIPPYKPIQHDTSSDSCSSPEKEIDSTMNSATTSATIIKITSSSGSAGGSSNVLNASSSAGISAGSSSGSGVSSSAKQRKSNASSKSSSSSSSSSSSSTGGAPNPSSSSVHSGSASNMTGGGSVLPGSSNIGNISNSLNNNLPGGSSSTSSAGNVPGGSGGIISASSGGATQSTSSQSSTAPGTTKSSASSSSSSSNSYKEKHSKSLSKSTSSKDKDGKDSSTNSANNNFTNSSASSTSSNSSSTREKSSSKLSKNKDSNQVPSATSSLSTTSSINTQPSSSTSTATAGSGGTGTHVSSSAASGLNSAPSTTNEHSNHAHTLSTNGTGAGSAAGKLQSVSNLSNSSSGFGSDLRSVSTSSSSTVNDSTGGFGSNSNSERENLSGAGSSASNMPGTIAPGTGGVSSSAATNLSTNKGGSSSSTANSLTSTSTSSGSSSNSSSKKRKADSAKSTSSISTSGSALEDNNSLISRYDIKDVQVALTPLTDFEKEIEKSSKRQRTELSPPTHQTSATAEVNAPLASSTSASIAVTASATAASAPPATGTTTLGSSISGNAGSTSSGNSSGVSATGGAQSAVGSGGYPKTESSKSSGTASAGSGSGSSSNTSSTKHGSNIKDISSSSNQQASTASSSSAPSLYVSVPLSTANVPGINLPTSSTSSSTTSESHSASSRSSGAQSQHQQQLSNALVGPPMGGSAGAFHGGTTSAGSSSVIQQQSGKSSPALGTLVSGNSGGSIISASGFPLPSGNLTATTTESGNLKISYEKQTTRVQQLQEQEAPPARRSRSRSGESGSSHHHAHAHHHHHHPTHHNSHHQQNPQQQQQLHQQQQQNASSHMHACTNSSSSTSTSTTSSSLSGGTAPATSSSNSKGPSRSGKKRGAAMNKSESTSVATTATPATVAATPAEKQSRHSSPHYSATPTPPPTSTLPPVVSSPVVMLQSLSSSSIDSPPATAAAGATSNSRNTRNNSSNGNHNGEQTSSSSSSSSSSSSGGGGTSGAANVVNLLDSPVNMSASGNYRSSSNSTGNALPAASSNASQAKPLNKKMLRAQQTQLYQQQQQQQQYAPPARSISPTNLSSASASNSASLTHLQQQQQSHQQHEDLEILQFTNTNTTASSNTPTSKPNNRTLDLSTASASSSSPSAVPATTSPLVVLSNQLPLNSVAASSSTGGLKFTYESQTQMDVPMMPVSAIKDSPPSSPGSEIGSAMHSATTAPGSLTGASTAATAQPGNVRKRGRKAKDATIAAAAAAAAAAAALSNSQQDLKDVRILQNGASNTPGNPAGSTPTPPATPASSNAVSSASSIITHTAAHMLGNQINPNSSVAQKLSEQLHMEVQDHSIYTPDSMNSQYAGVPFPGKQRNSTAVPSNATPAQNPLQSMFSGGGMNGNMPIPQSLEQLLERQWEQGSQFLMEQAQHFDIASLLNCLHQLQSENLRLEEHVTSLIARRDHLLAVNARLQIPLSTIASNTKAEAHGK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* : : .. . . ****:************.*********:.*.*********** ******:*********::* ******* :*****:***.**************.*.**:*****:*. :*::**.******:* *: .:* .**** *** .*:* ******* ****** *. ***:*****::*:.**:: * ... * * **: . * : ..*.. .. . . . : *.: * : :..::*... . .* *.. * .*: :. :* ** : .. ::*. .. .. . .*.*.* .: .*.. . . .. * *:.*. : . * :.: :** . ... .:::. .** .: : . . . . : . .: * : .. . . : * * .:*. . .:. .. .... : . :.. . ..: . : : .. .: : * . * ..: . ..*::.:* . * . . . .:: ..: : . .. * .. . ..* .: .* . : :. . .: :.. : ** .. : . :.:. .. . : : * .. .. :*..: : .*. . . ** . : : * .. .. : .:. *:* .. **: ::.. . . . : *: ..:. .:* : .: * .*. : . :: .:.* . . * . . : * . .. .: . .: : . *: .***.:. *. .:.. : . :: . : . * *:: : .. :*. *:. :: . :..: . .: .. :: . .*.: : * :*::* . . . :. .:.. * :* * .::: : : : : :.. .. . .::*.*::. .: :. ::. **: :.: ", "identical_positions": 219, "similar_positions": 384, "identity": "12.3%" }, { "cls_id": "homologset.agr.MGI:1329039", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WUZ6-1", "uniprot_id": "CCL17_MOUSE", "id": "Q9WUZ6-1", "name": "C-C motif chemokine 17", "aln": "MRSLQMLLLAALLLGTFLQHARAARATNVGRECCLDYFKGAIPIRKLVSWYKTSVECSRDAIVFLTVQGKLICADPKDKHVKKAIRLVKNPRP-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9ERE0-1", "uniprot_id": "CCL17_RAT", "id": "Q9ERE0-1", "name": "C-C motif chemokine 17", "aln": "MMSLQMLLLAALLLGTSLQHASAARATNVGRECCLDYFKGAIPIRKLVTWFRTSVECPKDAIVFETVQGRLICTDPKDKHVKKAIRHLKNQRL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q92583-1", "uniprot_id": "CCL17_HUMAN", "id": "Q92583-1", "name": "C-C motif chemokine 17", "aln": "MAPLKMLALVTLLLGASLQHIHAARGTNVGRECCLEYFKGAIPLRKLKTWYQTSEDCSRDAIVFVTVQGRAICSDPNNKRVKNAVKYLQSLERS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* .*:** *.:****: *** ***.*********:*******:*** :*::** :*.:***** ****: **:**::*:**:*:: ::. . ", "identical_positions": 55, "similar_positions": 26, "identity": "58.51%" }, { "cls_id": "homologset.agr.MGI:1329040", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O94907-1", "uniprot_id": "DKK1_HUMAN", "id": "O94907-1", "name": "Dickkopf-related protein 1", "aln": "MMALGAAGATRVFVAMVAAALGGHPLLGVSATLNSVLN-SNAIKNLPPPLGGAAGHPGSAVSAAPGILYPGGNKYQTIDNYQPYP--CAEDEECGTDEYCASPTRGGD--AGVQICLACRKRRKRCMRHAMCCPGNYCKNGICVSSDQNHF-RGEIEET--ITESFGNDH--STLDGYSRRTTLSSKMYHT-KGQEGSVCLRSSDCASGLCCARHFWSKICKPVLKEGQVCTKHRRKGSHGLEIFQRCYCGEGLSCRIQKDHHQASNSSRLHTCQRH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O54908-1", "uniprot_id": "DKK1_MOUSE", "id": "O54908-1", "name": "Dickkopf-related protein 1", "aln": "MMVVCAAAAVRFLAVFTMMALCSLPLLGASATLNSVLINSNAIKNLPPPLGGAGGQPGSAVSVAPGVLYEGGNKYQTLDNYQPYP--CAEDEECGSDEYCSSPSRGAAGVGGVQICLACRKRRKRCMRHAMCCPGNYCKNGICMPSDHSHFPRGEIEES--IIENLGNDHNAAAGDGYPRRTTLTSKIYHT-KGQEGSVCLRSSDCAAGLCCARHFWSKICKPVLKEGQVCTKHKRKGSHGLEIFQRCYCGEGLACRIQKDHHQASNSSRLHTCQRH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M1P605-1", "uniprot_id": "A0A8M1P605_DANRE", "id": "A0A8M1P605-1", "name": "", "aln": "------MRNMLSLLAVLTVYLAVWGGITVDAQVGSVLR--NSIRHLP-----AASSPSDAVSASPRVTG-------TVDSDAPPSPHCSADSECSIGEFCN---------GSRGVCLSCRKRRKRCARDGMCCAGNRCINGVCQLADAAAVGSADASPPGGNTDVSGVAVTRGQNFTHPRRTTVLSKPQQTQKGGEGETCLRSSDCLEGLCCARHFWSRICKPVLTEGQVCTRHRRKGAHGLEIFQRCDCGSGLTCRGQREKPGAE-SRNLHTCQPR", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .. * : ..* :.*** *:*::** *.. *..***.:* : *:*. * . *: *.**. .*:* .. :**:******** *..***.** * **:* :* . .: . . : * . :.****: ** :* ** **..******* **********:******.******:*:***:********* **.**:** *::: *. * .***** :", "identical_positions": 113, "similar_positions": 61, "identity": "40.79%" }, { "cls_id": "homologset.agr.MGI:1329041", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZH30-1", "uniprot_id": "D3ZH30_RAT", "id": "D3ZH30-1", "name": "mRNA-capping enzyme", "aln": "MAYNK---------IPPRWLNCPRRG-QPVAGRFLPLKTMLGPRYDSQVAEENRFHPSMLSNYLKSLKVKMSLLVDLTNTSRFYDRNDIEKEGIKYIKLQCKGHGECPTTENTETFIRLCERFNERSPPELIGVHCTHGFNRTGFLICAFLVEKMDWSIEAAVATFAQARPPGIYKGDYLKELFRRYGDIEEAPPPPVLPDWCFEDDD----------------------EEDEDEDGKK---DSEPGSSAS--FGKRRKERLKLGAIFLEGITVKGVTQVTTQPKLGEVQQKCHQFCGWEGSGFPG-----AQPVSMDKQNIRLLEQKPYKVSWKADGTRYMMLIDGTNEVFMIDRDNSVFHVSNLEFPFRKDLRMHLSNTLLDGEMIIDKVNGQAVPRYLIYDIIKFNAQPVGECDFN-IRLQCIEREIISPRHEKMKTGLIDKTQEPFSVRPKQFFDINISRKLLEGNFAKEVSHEMDGLIFQPIG-KYKPGRCDDILKWKPPSLNSVDFRLKITRMGGEGLLPQNVGLLYVGGYERPFAQIK-VTKELKQYDNKIIECKFENN-SWVFMRQRIDKSFPNAYNTAMAVCNSISNPVTKEMLFEFIDRCAAAAQGQKRKYPMDPDSE------LMPPPPPKRLHRPT-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O55236-1", "uniprot_id": "MCE1_MOUSE", "id": "O55236-1", "name": "mRNA-capping enzyme", "aln": "MAYNK---------IPPRWLNCPRRG-QPVAGRFLPLKTMLGPRYDSQVAEENRFHPSMLSNYLKSLKVKMSLLVDLTNTSRFYDRNDIEKEGIKYIKLQCKGHGECPTTENTETFIRLCERFNERSPPELIGVHCTHGFNRTGFLICAFLVEKMDWSIEAAVATFAQARPPGIYKGDYLKELFRRYGDIEEAPPPPVLPDWCFEDED----------------------EEDEDEDGKK---DSEPGSSAS--FSKRRKERLKLGAIFLEGITVKGVTQVTTQPKLGEVQQKCHQFCGWEGSGFPG-----AQPVSMDKQNIRLLEQKPYKVSWKADGTRYMMLIDGTNEVFMIDRDNSVFHVSNLEFPFRKDLRMHLSNTLLDGEMIIDKVNGQAVPRYLIYDIIKFNAQPVGDCDFN-IRLQCIEREIISPRHEKMKTGLIDKTQEPFSVRPKQFFDINISRKLLEGNFAKEVSHEMDGLIFQPIG-KYKPGRCDDILKWKPPSLNSVDFRLKITRMGGEGLLPQNVGLLYVGGYERPFAQIK-VTKELKQYDNKIIECKFENN-SWVFMRQRIDKSFPNAYNTAMAVCNSISNPVTKEMLFEFIDRCAAAAQGQKRKYPLDPDTE------LMPPPPPKRLHRPT-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60942-1", "uniprot_id": "MCE1_HUMAN", "id": "O60942-1", "name": "mRNA-capping enzyme", "aln": "MAHNK---------IPPRWLNCPRRG-QPVAGRFLPLKTMLGPRYDSQVAEENRFHPSMLSNYLKSLKVKMGLLVDLTNTSRFYDRNDIEKEGIKYIKLQCKGHGECPTTENTETFIRLCERFNERNPPELIGVHCTHGFNRTGFLICAFLVEKMDWSIEAAVATFAQARPPGIYKGDYLKELFRRYGDIEEAPPPPLLPDWCFEDDE----------------------DEDEDEDGKK---ESEPGSSAS--FGKRRKERLKLGAIFLEGVTVKGVTQVTTQPKLGEVQQKCHQFCGWEGSGFPG-----AQPVSMDKQNIKLLDLKPYKVSWKADGTRYMMLIDGTNEVFMIDRDNSVFHVSNLEFPFRKDLRMHLSNTLLDGEMIIDRVNGQAVPRYLIYDIIKFNSQPVGDCDFN-VRLQCIEREIISPRHEKMKTGLIDKTQEPFSVRNKPFFDICTSRKLLEGNFAKEVSHEMDGLIFQPTG-KYKPGRCDDILKWKPPSLNSVDFRLKITRMGGEGLLPQNVGLLYVGGYERPFAQIK-VTKELKQYDNKIIECKFENN-SWVFMRQRTDKSFPNAYNTAMAVCNSISNPVTKEMLFEFIDRCTAASQGQKRKHHLDPDTE------LMPPPPPKRPRPLT-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NY98-1", "uniprot_id": "MCE1_DANRE", "id": "Q6NY98-1", "name": "mRNA-capping enzyme", "aln": "MSQTG---------APPRWRNCPRRG-QPVAGKFLPMKTMLGPRYDDKVPEENRFHPSMLSNYLKSLKVKMGLLVDLTNTTRFYDRADIEKEGIKYVKLSCKGHGECPTAETTEMFIRLCEHFIEKTPTELIGVHCTHGFNRTGFLICAYLVEKMDWSIEAAVAAFAQARPPGIYKGDYLKELFRRYGDVEDAPAAPPLPEWCFDEDE----------------------EEDGEEDGSASAPASEPSSSHTG-QSKKKKERLKLGAVFLEGVSVKGVSQVTTQPKLGEIQRKCQQFSEWDRSGFPG-----AQPVSMDRKNIRMLEQNGYKVSWKADGTRYMMLIDGRNEVYMIDRDNSVFHIENLEFPFRKDLRIHLSNTLLDGEMIIDKVNGQPVPRYLIYDIIKFSGQPVGQCDFN-RRLLCIEKEIISPRFEKMKLGQIDKAKEPFSVRNKPFFDIHAARKLLEGSFTSQVSHEVDGLIFQPIG-KYKPGRCDDILKWKPPSHNSVDFRLKITKVGGEGLIPQTVGLLYVGNYDMPFAQMK-ITKDLKQYDNKIIECTFVNN-TWVFMRQRVDKSFPNAYDTAMAVCNSIQHPVTKEILLEFLERC---AQVQSRKNPADSD--------LMPPPPPKRSANSIPQ-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VY44-1", "uniprot_id": "Q9VY44_DROME", "id": "Q9VY44-1", "name": "mRNA-capping enzyme", "aln": "MALTNRDRERGSGPLPNRWLYCPRKSDTIIAERFLAFKTPLSNNFHDKMPIECTFQPEMLFEYCKTLKVKLGLWVDLTNTKRFYDRSAVEELGAKYIKLQCRGHGETPSPEQTHSFIEIVDNFINERPFDVIAVHCTHGFNRTGFLIVCYLVERLDCSVSAALAIFASARPPGIYKQDYINELYKRYEDTNAAPAAPEQPNWCLDYDDGNGDGFVQDNSSSTSQQAGEQDDDAEEVEGEDAGGDCDASTSDGQPRKKRRREMIIKNATFMAG--VPGVRQVSDQPRLGDLQRKVQDWCDWKKNGFPG-----AQPVSMDRENIKRLSEIPYRVSWKADGTRYMMLIDGRDEVYFFDRNHSCFQVENVTFVESRNLNEHLDGTLVDGEMVLDKIGETVTPRYLIYDIVRLSNRDVRDEPFYPNRLDYIKTEVIGPRILGMKHGIINQRLQAFSVRGKDFWDIWMSARLLGEKFSRTLAHEPDGLIFQPSKQPYTAGTCSDVFKWKPHELNSVDFRLKIITERGEGLLTKKVGFLYVGGHDAPYGRMQRLTKETRELDNRIVECTMNQFGNWDFMRERTDKKNPNSYNTARSVVDSIKHPVTKEYLLNFIASSGYRNDHVMMPPPINSHNQNHNHNHFYPHGHGQHQRRPCVNPTLGN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q01159-1", "uniprot_id": "MCE1_YEAST", "id": "Q01159-1", "name": "mRNA-capping enzyme subunit alpha", "aln": "--------------------------------MVLAMESRVAPEIPGLIQPG---------NVTQDLKMMVCKLLNSPKPTKTFPGSQPVSFQHSDVEEKLLAHDYY-----------VCEKTDGLRVLMFIVINPVTGEQ------GCFMIDRENN--YYLVNGFRFPRLPQKKKEELLETLQDG-TLLDGELVIQTNP-----------------------------------------------------MTKLQELRYLMFDCLAING---RCLTQSPTSSRLAHLGKEFFKPYFDLRAAYPNRCTTFPFKISMKHMDFSYQLVKVAKSLDKLPHLSDGLIFTPVKAPYTAGGKDSLLLKWKPEQENTVDFKLILDIPMVEDPSLPKDDRNR---WYYNYDVKPVFSLYVWQGGAD-----------VNSRLKHFDQPFDRKEFEILERTYRKFAELSVSDEEWQN--LKNLEQPLNGRIVECAK--NQETGAWEMLRFRDDKLN------GNHTSVVQKVLESINDSVSLEDLEEIVGDIK------RCWDERRANMAGGSG------RPLPSQSQNATLSTSKPVHS---QPPSNDKEPKYVDEDDWSD-----------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .*.::: :. . . : : : **: : :: .:..: : . . :: . .*. : :. .* :: . * : .::::: : : * .* * * : :: * : * :. . : .. : * : * . ..:*..: :: . .:*. . :**.: :: : * ::: . : . ..* : : ::. *. .:::. : . * **: . * : :..* :. : : :. : * :: : . : : :* *.: . :::::: . * : :: . . : : . : . :: : *:: : . * .:. : .*: .* . :* ::: ::: ", "identical_positions": 35, "similar_positions": 161, "identity": "5.34%" }, { "cls_id": "homologset.agr.MGI:1329042", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6YAT4-1", "uniprot_id": "SGCE_RAT", "id": "Q6YAT4-1", "name": "Epsilon-sarcoglycan", "aln": "MLLFWWWE----LGDPCAWTGKGRGTLKMSPATTGTFLLT-VYTLFSKVHSDRNVYPSAGVLFVHVLEREYFKGEFPPYPKPGEVSNDPITFNTNLMGYPDRPGWLRYIQRTPYSDGVLYGSPTAENVGKPTIIEITAYNRRTFETARHNLIINIMSAEEFPLPYQAEFFIKNMNVEEMLASEVLGDFLGAVKNVWQP---ERLNAINITSALDRGGRVPLPIKDMKEGVYVMVGADVAFSSCLREVENPQN-QLRCSQEMEPVITCDKKFR-TQFYIDWCKISLVDKTKQVSTYQEVVR-GEGILPDGGEYKP-------PSDSLKSRDYYTDFLVTLAVPSAVALVLFLILAYIMCCRREGVEKRNMQTPDIQLVHHSSIQKSTKELRDMSKNREIAWPLSTLPVFHPVTGEIIPPMHT-DNYDSTNMPLMQTQPNLPHQTQIPQQQTTGKWYP---------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70258-1", "uniprot_id": "SGCE_MOUSE", "id": "O70258-1", "name": "Epsilon-sarcoglycan", "aln": "MLLFWWWE----LGDPCAWTGKGRGTLKMSPATTGTFLLT-VYTLFSKVHSDRNVYPSAGVLFVHVLEREYFKGEFPPYPKPGEVSNDPITFNTNLMGYPDRPGWLRYIQRTPYSDGVLYGSPTAENVGKPTIIEITAYNRRTFETARHNLIINIMSAEEFPLPYQAEFFIKNMNVEEMLASEVLGDFLGAVKNVWQP---ERLNAINITSALDRGGRVPLPINDMKEGVYVMVGADVAFSSCLREVENPQN-QLRCSQEMEPVITCDKKFR-THFHIDWCKISLVDKTKQVSTYQEVVR-GEGILPDGGEYKP-------PSDSLKSRDYYTDFLVTLAVPSAVALVLFLILAYIMCCRREGVEKRDMQTPDIQLVHHSSIQKSTKELRDMSKNREIAWPLSTLPVFHPVTGEVIPPTHT-DNYDSTNMPLMQAQQNLPHQTQIPQPQTTGKWYP---------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43556-1", "uniprot_id": "SGCE_HUMAN", "id": "O43556-1", "name": "Epsilon-sarcoglycan", "aln": "MQLPRWWE----LGDPCAWTGQGRGTRRMSPATTGTFLLT-VYSIFSKVHSDRNVYPSAGVLFVHVLEREYFKGEFPPYPKPGEISNDPITFNTNLMGYPDRPGWLRYIQRTPYSDGVLYGSPTAENVGKPTIIEITAYNRRTFETARHNLIINIMSAEDFPLPYQAEFFIKNMNVEEMLASEVLGDFLGAVKNVWQP---ERLNAINITSALDRGGRVPLPINDLKEGVYVMVGADVPFSSCLREVENPQN-QLRCSQEMEPVITCDKKFR-TQFYIDWCKISLVDKTKQVSTYQEVIR-GEGILPDGGEYKP-------PSDSLKSRDYYTDFLITLAVPSAVALVLFLILAYIMCCRREGVEKRNMQTPDIQLVHHSAIQKSTKELRDMSKNREIAWPLSTLPVFHPVTGEIIPPLHT-DNYDSTNMPLMQTQQNLPHQTQIPQQQTTGKWYP---------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9P1Q4-1", "uniprot_id": "A0A8M9P1Q4_DANRE", "id": "A0A8M9P1Q4-1", "name": "Epsilon-sarcoglycan", "aln": "MALPDVFVGLIVVVNVCSVSGTHAQTRALIDSKQRSVFYSGVVTILSKSHADRNVYPSAGVLFVHVLEREYFKGEFPPYPKAGDTSNDPITFNTNLRGFPDRPGWLRYIQRTSHSDGVLYGSPTADHVGKPTIIEITAYNKRTFETARHNLVINIMSTEEFPLPYQAEFYIKNMNVEEMLASEVLGDFLGAVKNVWQP---ERLNAINITSALDRGGRVPLPINDLKEGVYVMVGADVQFSSCLREVETPQN-QLRCSQEMEPVISCDKKFR-AQFNIDWCKISLVDITKVVPVHSNRPDPGTGVLPDIGEYNP-------PSESLKSRDYFADFLITLAVPSAVATVLFIILGYSMCCRREGVEKRNMQTPDIQLVHHSSIQKSTKELRGMSKNREISWPLSTLPVFHPVSGEVVPPIHP-DNYETTSMPLMQTQTNLQNQIQIPQQQTSGDNYCMSTFRR---------------LEVNGIPEERKVAEALNL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9PF78-1", "uniprot_id": "M9PF78_DROME", "id": "M9PF78-1", "name": "", "aln": "--------------------------MKFLN------LIVVVLALICNEVQGLKLQANVGELFTYKIEPQLFN-------WTHQVISQQFRYRPSLKNYPDLPSWMRYMYSHEYHAGFLYGTPPASSAGKDLSLDVVALNRQNYETRR--VVVTMFVAHKFPTPNVVQMKINNLNWVHLMDPGRRENLRNIFRNDLWPNSKEDLSVVFMESAVNMGGRLPLRP-QQREGVIVHVGSFAQFSPRLQELQEEVRPLYKLPSCTYKRTSVQKIFENVGFKLDWCAFRMVGMESPTEILFHSGKQNEQQMPDDLNQRQEDRWMGIAREDVPERNYIDEFAFAFAIPGMIFAILIGMLSAVLCFQHEKFYDPHSEFFFANIFHICEESCAPQSASSDSGADDGSESSSNSDYPMASTVQMVQCSDSKSNQPITTLKSLKDPNFLLDNTSMRSQSPNNSFYQLDCGNSSIYARPKPPPYKGGTLGRNGVDIXQTSPRVLYC", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : * :::.: . :: ...* **.: :* : *: . : .: : :...* .:** *.*:**: : *.***:*.*. .** :::.* *::.:** * :::.:: :..** * .:: *:*:* .:: . :: . .:* * * *..: : **:: ***:** : :*** * **: . **. *:*:: . : .. : :* *. . * :*** : :*. . . . . :** : . . :.: .*:* :* .::*:*. : :*: :*. :* ::* . . . : ::.* . . :.:. . * : : . *. . : ::: .. .* *.: :: * .: .: . ..... * ", "identical_positions": 78, "similar_positions": 163, "identity": "15.76%" }, { "cls_id": "homologset.agr.MGI:1329044", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63400-1", "uniprot_id": "CLD3_RAT", "id": "Q63400-1", "name": "Claudin-3", "aln": "MSMGLEITGTSLAVLGWLCTIVCCALPMWRVSAFIGSSIITAQITWEGLWMNCVVQSTGQMQCKMYDSLLALPQDLQAARALIVVSILLAAFGLLVALVGAQCTNCVQDETAKAKITIVAGVLFLLAAVLTLVPVSWSANTIIRDFYNPLVPEAQKREMGTGLYVGWAAAALQLLGGALLCCSCPPREK-YAPTKILYSAPRSTGPGTGTGTAYDRKDYV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z0G9-1", "uniprot_id": "CLD3_MOUSE", "id": "Q9Z0G9-1", "name": "Claudin-3", "aln": "MSMGLEITGTSLAVLGWLCTIVCCALPMWRVSAFIGSSIITAQITWEGLWMNCVVQSTGQMQCKMYDSLLALPQDLQAARALIVVSILLAAFGLLVALVGAQCTNCVQDETAKAKITIVAGVLFLLAALLTLVPVSWSANTIIRDFYNPLVPEAQKREMGAGLYVGWAAAALQLLGGALLCCSCPPRDK-YAPTKILYSAPRSTGPGTGTGTAYDRKDYV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15551-1", "uniprot_id": "CLD3_HUMAN", "id": "O15551-1", "name": "Claudin-3", "aln": "MSMGLEITGTALAVLGWLGTIVCCALPMWRVSAFIGSNIITSQNIWEGLWMNCVVQSTGQMQCKVYDSLLALPQDLQAARALIVVAILLAAFGLLVALVGAQCTNCVQDDTAKAKITIVAGVLFLLAALLTLVPVSWSANTIIRDFYNPVVPEAQKREMGAGLYVGWAAAALQLLGGALLCCSCPPREKKYTATKVVYSAPRSTGPGASLGTGYDRKDYV", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**********:******* ******************.***:* *******************:********************:***********************:******************:********************:**********:**************************:* *:.**::**********:. **.*******", "identical_positions": 198, "similar_positions": 17, "identity": "90.0%" }, { "cls_id": "homologset.agr.MGI:1329045", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M656-1", "uniprot_id": "F1M656_RAT", "id": "F1M656-1", "name": "Tubby-like protein", "aln": "MGVGDSAGCGCQGRGPTSSILSSRAAASWGLDADATGRAGMEAARCAPGSRGDSAFEDETLRLRQLKLDNQRALLEKKQRKKRLEPLMVQPNPEARLRRLKPRGSEEHTPLVDPQTPCSDVILHGIDGPAAFLKPEAQDLESKPQVLSVGSSPTPEEGTEGSADGESPVETASKPDLQEILQKHGILSSVNYDEEPDEEAEDEGENLSSLPAQSEKESAGASQKAASDTGASGMTAQQGDAQLGEVENLEDFAYSPAPRGVTVKCRVTRDKKGMDRGLFPTYYMHLEKEENRKIFLLAGRKRKKSKTSNYLVSTDPTDLSREGESYIGKLRSNLMGTKFTVYDHGVNPVKAQGLVEKAHTRQELAAICYETNVLGFKGPRKMSVIIPGMNMNHERIPFRPRN-EHESLLSKWQNKSMENLIELHNKAPVWNDDTQSYVLNFHGRVTQASVKNFQIVHGNDPDYIVMQFGRVADDVFTLDYNYPLCALQAFAIGLSSFDSKLACE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88413-1", "uniprot_id": "TULP3_MOUSE", "id": "O88413-1", "name": "Tubby-related protein 3", "aln": "----------------------------------------MEAARCAPGPRGDSAFDDETLRLRQLKLDNQRALLEKKQRKKRLEPLMVQPNPEARLRRLKPRGSEEHTPLVDPQMPRSDVILHGIDGPAAFLKPEAQDLESKPQVLSVG-SPAPEEGTEGSADGESPEETAPKPDLQEILQKHGILSSVNYDEEPDKE-EDEGGNLSSPSARSE-ESAAASQKAASETGASGVTAQQGDAQLGEVENLEDFAYSPAPRGVTVKCKVTRDKKGMDRGLFPTYYMHLEREENRKIFLLAGRKRKKSKTSNYLVSTDPTDLSREGESYIGKLRSNLMGTKFTVYDHGVNPVKAQGLVEKAHTRQELAAICYETNVLGFKGPRKMSVIIPGMNMNHERIPFRPRN-EHESLLSKWQNKSMENLIELHNKAPVWNDDTQSYVLNFHGRVTQASVKNFQIVHGNDPDYIVMQFGRVADDVFTLDYNYPLCALQAFAIGLSSFDSKLACE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75386-1", "uniprot_id": "TULP3_HUMAN", "id": "O75386-1", "name": "Tubby-related protein 3", "aln": "----------------------------------------MEASRCRLSPSGDSVFHEEMMKMRQAKLDYQRLLLEKRQRKKRLEPFMVQPNPEARLRRAKPRASDEQTPLVNCHTPHSNVILHGIDGPAAVLKPDEVHAPSVS-------SSVVEEDAENTVD------TASKPGLQERLQKHDISESVNFDEE------TDG--ISQSACLERPNSASSQNSTDTGTSGSATAAQPADNLLGDIDDLEDFVYSPAPQGVTVRCRIIRDKRGMDRGLFPTYYMYLEKEENQKIFLLAARKRKKSKTANYLISIDPVDLSREGESYVGKLRSNLMGTKFTVYDRGICPMKGRGLVGAAHTRQELAAISYETNVLGFKGPRKMSVIIPGMTLNHKQIPYQPQN-NHDSLLSRWQNRTMENLVELHNKAPVWNSDTQSYVLNFRGRVTQASVKNFQIVHKNDPDYIVMQFGRVADDVFTLDYNYPLCAVQAFGIGLSSFDSKLACE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q86PC9-1", "uniprot_id": "TULP_DROME", "id": "Q86PC9-1", "name": "Protein king tubby", "aln": "------------------------MSGINSRNQKMEQQRQLMEAYIRQKRASPGMVQASDLQINRPMSGMRSNSRELHAYDGPMQFISSPQNPDQILTNGSPGGINPVAMNTSRNHSNNMRSLSTINQEADLIEEISSHELEDEESSPVTVIEQHQQSASHSAN--------STQSQKPRARQHSFSDNLDEDDYTNRN--VAGAAPVRPAGMASSPYKDATLDGSSNGTGNGTGGESEGDVIGNID---QFVMQPAPQGVLYKCRITRDRKGMDRGLFPIYYLHLERDYGKKIFLLGGRKRKKSKTSNYIVSCDPTDLSRNADGFCGKLRSNVFGTSFTVFDNGNK-------ESTESPRLDLAVIIYDTNILGFKGPRNMTVILPGMTEDDQRVKISSADPKQQGILDLWKMKNMDNIVELHNKTPVWNDETQSYVLNFHGRVTQASVKNFQLVHDSDPEYIVMQFGRTSEDVFTMDYRYPLCAMQAFAIALSSFDGKIACE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . . .. . :::.: . : * : . :: : **: * . .* . : : .. : . . * *: * .:: . . ::.:. :.: .. . : ::*.: ..:: *: * . : . : ... .: . :*::: :*. .***:** :*:: **::******** **::**:: .:*****..********:**::* **.****:.:.: ******::**.***:*.* .* :**.* *:**:*******:*:**:***. :.::: . : :::.:*. *: :.*:*::*****:****.:********:************:** .**:********.::****:**.*****:***.*.*****.*:***", "identical_positions": 157, "similar_positions": 147, "identity": "31.15%" }, { "cls_id": "homologset.agr.MGI:1330223", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F7FL77-1", "uniprot_id": "F7FL77_RAT", "id": "F7FL77-1", "name": "", "aln": "--------------------------------MSEIKKQ--KTDQQKSTNVVYQAHHVSRNKRGQVVGTRGGFRGCTVWLTGLSGAGKTTISFALEEYLVSHAIPCYSLDGDNVRHGLNKNLGFSAGDREENIRRIAEVAKLFADAGLVCITSFISPFAKDRENARKIHESAGLPFFEIFVDAPLNICESRDVKGLYKRARAGEIKGFTGIDSNYEKPETPECVLKTNLSSVSDCVQQVVELLQEQSIVPHTT--IKGIHELFVPE-NKIDQIRAELETLPSLPITKLDLQWVQILSEGWATPLKGFMREKEYLQTLHFDTLLDGVILRDGVINMSIPIVLPVSGDDKARLEGCSKFALMYEGRRVALLQDPEFYEHRKEERCSRVWGTASAKHPHIKMVMEGGDWLVGGDLQVLERIRWNDGLDQYRLTPLELKQKCKDMDADAVFAFQLRNPVHNGHALLMQDTRRRLLERGYKHPVLLLHPLGGWTKDDDVPLDWRMKQHAAVLEEGILDPKSTIVAIFPSPMLYAGPTEVQWHCRCRMIAGANFYIVGRDPAGMPHPETKK----DLYEPTHGGKVLSMAPGLTSVEIIPFRVAAYNKIKKAMDFYDPARHDEFDFISGTRMRKLAREGEDPPDGFMAPKAWKVLTDYYRSLEKIN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88428-1", "uniprot_id": "PAPS2_MOUSE", "id": "O88428-1", "name": "Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2", "aln": "--------------------------------MSANFKMNHKRDQQKSTNVVYQAHHVSRNKRGQVVGTRGGFRGCTVWLTGLSGAGKTTISFALEEYLVSHAIPCYSLDGDNVRHGLNKNLGFSAGDREENIRRIAEVARLFADAGLVCITSFISPFAKDRENARKIHESAGLPFFEIFVDAPLNICESRDVKGLYKRARAGEIKGFTGIDSDYEKPETPECVLKTNLSSVSDCVQQVVELLQEQNIVPHTT--IKGIHELFVPE-NKVDQIRAEAETLPSLPITKLDLQWVQILSEGWATPLKGFMREKEYLQTLHFDTLLDGVVPRDGVINMSIPIVLPVSADDKARLEGCSKFALMYEGRRVALLQDPEFYEHRKEERCSRVWGTATAKHPHIKMVMESGDWLVGGDLQVLERIRWDDGLDQYRLTPLELKQKCKDMNADAVFAFQLRNPVHNGHALLMQDTRRRLLERGYKHPVLLLHPLGGWTKDDDVPLEWRMKQHAAVLEERVLDPKSTIVAIFPSPMLYAGPTEVQWHCRCRMIAGANFYIVGRDPAGMPHPETKK----DLYEPTHGGKVLSMAPGLTSVEIIPFRVAAYNKIKKAMDFYDPARHEEFDFISGTRMRKLAREGEDPPDGFMAPKAWKVLTDYYRSLEKTN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95340-1", "uniprot_id": "PAPS2_HUMAN", "id": "O95340-1", "name": "Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2", "aln": "--------------------------------MSGIKKQK-TENQQKSTNVVYQAHHVSRNKRGQVVGTRGGFRGCTVWLTGLSGAGKTTISFALEEYLVSHAIPCYSLDGDNVRHGLNRNLGFSPGDREENIRRIAEVAKLFADAGLVCITSFISPFAKDRENARKIHESAGLPFFEIFVDAPLNICESRDVKGLYKRARAGEIKGFTGIDSDYEKPETPERVLKTNLSTVSDCVHQVVELLQEQNIVPYTI--IKDIHELFVPE-NKLDHVRAEAETLPSLSITKLDLQWVQVLSEGWATPLKGFMREKEYLQVMHFDTLLD-----DGVINMSIPIVLPVSAEDKTRLEGCSKFVLAHGGRRVAILRDAEFYEHRKEERCSRVWGTTCTKHPHIKMVMESGDWLVGGDLQVLEKIRWNDGLDQYRLTPLELKQKCKEMNADAVFAFQLRNPVHNGHALLMQDTRRRLLERGYKHPVLLLHPLGGWTKDDDVPLDWRMKQHAAVLEEGVLDPKSTIVAIFPSPMLYAGPTEVQWHCRSRMIAGANFYIVGRDPAGMPHPETKK----DLYEPTHGGKVLSMAPGLTSVEIIPFRVAAYNKAKKAMDFYDPARHNEFDFISGTRMRKLAREGENPPDGFMAPKAWKVLTDYYRSLEKN-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8IQV1-1", "uniprot_id": "Q8IQV1_DROME", "id": "Q8IQV1-1", "name": "", "aln": "MFTRCANSLGLYHNNINNNNSACCAASPKRSCLPSVEKPE-DACLQVATNVTEQKHHVTRETRGKNLGLCRGFRGCTVWLTGLSGAGKTSIAFELEAYLVSRGIPAYGLDGDNIRTGLNKNLGFTPADREENIRRVGEVAKLFADSGVVAICSFVSPFADDREMARKIHKDAGLKFYEIFVDTPLDVCETRDVKGLYKKAREGVIKGFTGITQEYERPQMPELVVNTHGYTVRESTQKLVTLLEQEGIIPRSLRDVDLLPELYPSESIATEALRHEAESLQAIEISTVELQWVQVLAEGWAYPLRGFMREDEYLQTLHFNTLQSG-MDGSYRENHSVPIVLSATQADKDRLDGCSSLTLKYQGKAVAILRRPEFYFQRKEERLARQFGTSNPNHPYSKQVYESGDYLVGGDLAVIERIRWEDGLDQYRLTPNELRRRFKELNADAIFAFQLRNPIHNGHALLMQDTRRQLLERGFKQPVLLLHPLGGWTKDDDVPLDVRMKQHQAVLDAGVLRREDTVLAIFPSPMMYAGPTEVQWHAKARMNAGANFYIVGRDPAGMPHPAKETYPDGNLYDATHGARVLKMAQGLDSMEILPFRVAAYDKSASRMAFFEPKRKDEFEFISGTKMRTLAKTGASPPDGFMEPEAWRILATYYQNLPQS-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q02196-1", "uniprot_id": "KAPS_YEAST", "id": "Q02196-1", "name": "Adenylyl-sulfate kinase", "aln": "----------------------------------------------MATNITWHPN-LTYDER-KALRKQD---GCTIWLTGLSASGKSTIACALEQLLLQKNLSAYRLDGDNIRFGLNKDLGFSEKDRNENIRRISEVSKLFADSCAISITSFISPYRVDRDRARELHKEAGLKFIEIFVDVPLEVAEQRDPKGLYKKAREGVIKEFTGISAPYEAPKAPELHLRTDQKTVEECATIIYEYLISEKIIRKHL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P08536-1", "uniprot_id": "MET3_YEAST", "id": "P08536-1", "name": "Sulfate adenylyltransferase", "aln": "-----------------------------------MPAPHGGILQDLIARDALKKNELLSEAQSSDILVWNLTPRQLCDIELILNGGFSPLTGFLNENDYSSVVTDSRLADGTLWT-IPITLDVDEAFAN-QIKPDTRIALFQDDEIPIAILTVQDVYKPNK----------TIEAEKVFRGDPEHPAISYLFNVAGDYYVGGSLEAIQ-LPQHYDYPGLRKTPAQLRLEFQSRQWDRVVAFQTRNPMHRAHR-----------------------ELTVRAAREANAKVLIHPVVGLTKPGDIDHHTRVRVYQEIIKR-----------YPNGIAFLSLLPLAMRMSGDREAVWHAIIRKNYGASHFIVGRDHAGPGKNSKGVDFYGP-----YDAQELVESYKHELDIEVVPFRMVTYLPDEDRYAPIDQIDTTKTRTLN-------------------ISGTELRRRLRVGGEIPEWFSYPEVVKILRESNPPRPKQGFSIVLGNSLTVSREQLSIALLSTFLQFGG--------------GRYYKIFEHN------------------NKTELLSLIQDFIGSGSGLIIPNQWEDDKDS--------VVGKQNVYLLDTSSSADIQLESADEPISHIVQKVVLFLEDNGFFVF---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. . : : : : : . : : : .* :.:: *: . :. * ...: : *.. : :*: .:: : * :.* :. . : :: : ::* . * . . : . * :: : : *: * : . : : : ", "identical_positions": 12, "similar_positions": 61, "identity": "1.82%" }, { "cls_id": "homologset.agr.MGI:1330233", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LAZ2-1", "uniprot_id": "A0ABK0LAZ2_RAT", "id": "A0ABK0LAZ2-1", "name": "Telethonin", "aln": "LGFLYRLGYVILLVKGPHYDKPLSSLNKGEQAEDSAKVARGCPRAWSEVVFAACQTPGGATLRTQAPSRASRRLWKLTSDLRAIRIWVPQPPPWIQSPITTKLSCQVSEENQERREAFWAEWKDLTLSTRPEEGCSLHEEDTQRHETYHRQGQCQAVVQRSPWLVMRLGILGRGLQEYQLPYQRVLPLPIFTPTKVGATKEEREETPIQLRELLALETALGGQCVERQDVAEITKQLPPVVPVSKPGPLRRTLS---RSMSQEAQRG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70548-1", "uniprot_id": "TELT_MOUSE", "id": "O70548-1", "name": "Telethonin", "aln": "-------------------------------------------------------------------------------------------------MATSELSCQVSEENQERREAFWAEWKDLTLSTRPEEGCSLHEEDTQRHETYHRQGQCQAVVQRSPWLVMRLGILGRGLQEYQLPYQRVLPLPIFTPTKVGASKEEREETPIQLRELLALETALGGQCVERQDVAEITKQLPPVVPVSKPGPLRRTLS---RSMSQEAQRG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15273-1", "uniprot_id": "TELT_HUMAN", "id": "O15273-1", "name": "Telethonin", "aln": "-------------------------------------------------------------------------------------------------MATSELSCEVSEENCERREAFWAEWKDLTLSTRPEEGCSLHEEDTQRHETYHQQGQCQVLVQRSPWLMMRMGILGRGLQEYQLPYQRVLPLPIFTPAKMGATKEEREDTPIQLQELLALETALGGQCVDRQEVAEITKQLPPVVPVSKPGALRRSLS---RSMSQEAQRG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9P8J3-1", "uniprot_id": "A0A8M9P8J3_DANRE", "id": "A0A8M9P8J3-1", "name": "", "aln": "----------------------------------------------------------------------------------------MHCLSRTPRSYLLNSYSDLQETDELSRESYEATWLDLLMETRPEYKMTLAEKDSMKKESYESKQVVHFTVRRFPNQTIQMGRDREPMQEYRLPYKNILPIPIFVPRDVTQPDVTRSPSPS-VKSSTDTEASLSGVCLHKREISSITEHKPMVIQPRSPDFRASSLISPPRDTLRFQRRE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .::.* : **:: * * ** :.**** :* *:*: ::*:*. : : *:* * :::* . :***:***:.:**:***.* .: .. *. :* ::. *::*.* *:.:::::.**:: * *: .*. :* *. : :* ", "identical_positions": 46, "similar_positions": 60, "identity": "17.23%" }, { "cls_id": "homologset.agr.MGI:1330235", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ES14-1", "uniprot_id": "GBRE_RAT", "id": "Q9ES14-1", "name": "Gamma-aminobutyric acid receptor subunit epsilon", "aln": "-----MLPKVLLMLLNMFLALQWRV-GPHIKLENKPPAQDKVVFGPQPQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PSGKKLPARETELTADHTTERPRGKLTRAS---QILNTILSNYDHKLRPSIG-EKPTVVTVKVFVNSLGPISILDMEYSIDIIFYQTWYDERLRYNDTFETLILHGNVVSQLWIPDTFFRNSKRTQEYDITIPNQMALIHKDGKVLYTVRMTIDARCSLHMLNFPMDSHSCPLSFSSFSYDEHEMIYKWENFKLKIDAKNTWKLLEFDFTGVNNKTEIIST----------------------------------------------------------------------------PVGDFMVMTFFFNVSRRFGFIVFQNYIPSSVTTMLSWVSFWIKIEAAAARASVGVSSVLTMATLGTFSRKNFPRVSYLTALDFYIAICFVLCFCTLLEFTVLNFLTYN--------------------------NIERQASPKFYQFPTNSRANARTRARARTRARARARARQQQE-------------------------VFVCEIVTYEENAEEG-----YQWSPRSRRPQCPWRRCGRSYVC--FRVLRKYFCMVPGCEGNNWQRGRICIHVYRLDNYSRVLFPITFFFFNVVYWVICLNL-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2AMW3-1", "uniprot_id": "A2AMW3_MOUSE", "id": "A2AMW3-1", "name": "Gamma-aminobutyric acid receptor subunit epsilon", "aln": "-----MLPKVLLMLLNMFLALQWRV-GPHVNLENKPPAQDKVVFGPQPQPVPQPLTPPESPAGDTVVFGPQPQPQAESPGHDDVVFSSQPQPMPQPQPMPEPQPQPEPEPEPQPQPQPQPLAGRQPLPQPLPWPMPQPQPEPEPEPEPEPEPEPEPEPEPEPEPEPQPEPQPQPLAGRQPLPQPLPWPLPLPLPEPQPEPQPDPQPEPQPEPQPEPQPEPQPEPQTPGQVQAGRQPRPRPQPEPQPQPEPQPEPQPEPQPQPEPEPEPQPEPEPQPEPEPQPEPQPEPQPEPKPEPEPQPEPEPQPEPQPEPQPEPQPEPKPEPEPQPEPKPEPEPQPEPEPEPEPEPEPQPEPEPKPEPQPEPEPEPEPEPEPEPEPEPEPEPEPEPESESELDLEPEPEPHPHPHPHPHPHPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEMKSEPQSQLEPQPSGKKLPAKEPELTVDCMTERPGGKLTRAS---RILNTILSNYDHKLRPGIG-EKPTVVTVEVIVNSLGPISTPDMEYSIDIIFHQTWYDERLRYNDTFETLILHGNVVSQLWIPDTFFRNSKRTQEYDITIPNQMALIHKDGKVLYSVRMTIDARCSLHMLNFPMDSHSCPLSFSSFSYDDSEMIYKWENFKLEINAKNTWKLLEFDFTGVNNKTEIIST----------------------------------------------------------------------------PFGDFMVMTFFFNVSRRFGFIVFQNYVPSSVTTMLSWVSFWIKIEAAAARASVGVSSVLTMATLGTLSCKNFPRVSYLTALDFYIAICFVLCFCTLLEFAVLNFLTYN--------------------------NIKRQASLKVYQLPTNSRANARTRARARTRARARARARQQQE-------------------------VFVCEIVTYEENAEEG-----YQWSPRSRRPQCPWRRCGRSYVC--FRVLRKYFCMAPGCEGGSWQRGRICIHVYRLDNYSRVLFPITFFFFNVLYWLICLNL-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P78334-1", "uniprot_id": "GBRE_HUMAN", "id": "P78334-1", "name": "Gamma-aminobutyric acid receptor subunit epsilon", "aln": "-----MLSKVLPVLLGILLILQSRVEGPQTESKNEASSRD-VVYGPQPQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PLENQLLSEETKSTETETGSR-VGKLPEAS---RILNTILSNYDHKLRPGIG-EKPTVVTVEISVNSLGPLSILDMEYTIDIIFSQTWYDERLCYNDTFESLVLNGNVVSQLWIPDTFFRNSKRTHEHEITMPNQMVRIYKDGKVLYTIRMTIDAGCSLHMLRFPMDSHSCPLSFSSFSYPENEMIYKWENFKLEINEKNSWKLFQFDFTGVSNKTEIITT----------------------------------------------------------------------------PVGDFMVMTIFFNVSRRFGYVAFQNYVPSSVTTMLSWVSFWIKTESAPARTSLGITSVLTMTTLGTFSRKNFPRVSYITALDFYIAICFVFCFCALLEFAVLNFLIYN--------------------------QTKAHASPKLRHPRINSRAHARTRARS------RACARQHQE-------------------------AFVCQIVTTEGSDGEERPSCSAQQPPSPGSPEGPRSLCSKLACCEWCKRFKKYFCMVPDCEGSTWQQGRLCIHVYRLDNYSRVVFPVTFFFFNVLYWLVCLNL-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q24352-1", "uniprot_id": "GBRAL_DROME", "id": "Q24352-1", "name": "Gamma-aminobutyric acid receptor alpha-like", "aln": "---MCTMPATRDASGSGDASTDLIAARSLSSHQGQRSNLRIFKLLISCCLLMLCIYPNAWPWSIG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PGSGPFSVSADSIKGRGDTHRLGEMGTSLSSSLPSSWLTQSNNHAN-ISELLDNLLRGYDNSIRPDFG-GPPATIEVDIMVRSMGPISEVDMTYSMDCYFRQSWVDKRLAFEGAQDTLALSVSMLARIWKPDTYFYNGKQSYLHTITTPNKFVRIYQNGRVLYSSRLTIKAGCPMNLADFPMDIQKCPLKFGSFGYTTSDVIYRWNKERPPVAIAEDMKLSQFDLVDCPAGNLTDIVYKAAAPRPQRRPFNNKDPPRPTSKVMTTFAGPAAKNQHVRGTGLKLDKGAFGTGRDATGGSGSTTGLSGTITLETNHPSEYSMLMVNFHLQRHMGNFLIQVYGPCCLLVVLSWVSFWLNREATADRVSLGITTVLTMTFLGLEARTDLPKVSYPTALDFFVFLSFGFIFATILQFAVVHYYTKYGSGECYFIIEELDSESGESETEPLTSDFRGSTESKIYEVIPLSMCAISMPPPPTRLGMLTSRNRRPRNRRHGLWSMKLLGLFDWRRRRKPP----RADSDEDEDDEQTQLRANEAPTTSAAAAAAQAAAQAARISPPTGGRRRMSYYRREEMEARRKGKRTPQYNSVSKIDRASRIVFPLLFILINVFYWYGYLSRSSRILANTPDAST", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VXL9-1", "uniprot_id": "Q9VXL9_DROME", "id": "Q9VXL9-1", "name": "", "aln": "MVRVSLVPFIIIGFMAHFCACEDVTSSDLLYIKTMGPSAILTKMPNITNEFSSRIFS---SFRIL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PSSKPK--TNGSLKRSQNATNLSYSSSEISNQRRVRRKAAADMLSRNISMILENLLKRYEQSQLPTHGQGVPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDKRLSFKGPIKSLSLSIKMLDKIWRPDTYFYNGKHSQIHMITVPNKLLRLDQNGGILYSMRLTIKATCPMELQNFPMDRQSCPLVIGSYGYINQQLIYEWKNQDDAVSFVPGMTLNQFDLISMMHRNFTTVR----------------------------------------------------------------------------REGDFSVLHVAFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREATSDRVSLCVTSVLTLSTISLDSRTDLPKVKYATALDWFLLMSFLYCIATLLEFAGVHYFTKLGSGESPQLEDQWEDICIANSLSDHAGEVDGDGEADADPFADEDSSNGSENDDNEAGASESVESKSGVCVCNKNDALGLEYEVSLQNSLAGAGFLKRNAIFCPTYNDPSYILPNTMERTTQTEPPAVSRLHQMWMCLKSDNSFRKQRERNAAAQKSEQGGANCYVNSVSLIDRVARIAFPMSFAFLNLLYWWAYGMYKKEFSWSNMKS--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. : . : . .* .. : : :*:.:* *::. * * *:.: ..: :.*:**:* ** *::* * * * *:** ::.. .:* * .:: ::* ***:* *.*:: : ** **:: : ::* :**: *:**.* *.:.: **** :.*** :.*:.* ::**.*:: : .* :**: . . .:: :: . *::.*: * . :* * *. : .:*******:: *::. *.*: :::***:: :. : .::*:*.* ****::: :.* :.::*:*: ::: : . . . . : . .. . . . . * :*. :*: **: * ::*:.** ", "identical_positions": 95, "similar_positions": 149, "identity": "8.85%" }, { "cls_id": "homologset.agr.MGI:1330237", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZHQ6-1", "uniprot_id": "D3ZHQ6_RAT", "id": "D3ZHQ6-1", "name": "", "aln": "MSSYQQKQPFVAPPQPQQHQVKQPCQPPPQGKFVPIATSEPCHTGVPQPGNTKIPEPCSTKVPEPGYTVVLEPDYTTVPGSCSTNVTKPDYTTIPGPCSTNIPGPDNVVPESCSTNITEPNYTTIPGPCSTNIPGPD-TMVPGSCSTSTTEPNYTTIHGPCTTNIPDPGCAMVPGPCSTNISEPSSEPCSTNVREPGYLNASEPTNAKVPDQGYTKIPDQGYSKVPEPCQSRTPEVCPTTVTPGLAQQKTKQK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O09116-1", "uniprot_id": "SPRR3_MOUSE", "id": "O09116-1", "name": "Small proline-rich protein 3", "aln": "MSSYQQKQPFVPPPQPEQHQVKQPCQPPPQGKFVPIATSEPCHTDVPQPGNTKIPEPCSTKVPEPGNTVVLEPDYTTMPGPCSTNITEPDYTTIPGPCST---------------NITEPDYTTIPGPCSTNIPGPDRTVVPGSCSTNITEPDYTTIPGPSSTKIPDPGCAMVPGPSPSSTSEPSSEPCSINVREPGYMNASEPTHAKVPDQGYTKIPDQGSSKVPEPCQSRVPEVCPPTVTPVSAKQKTKQK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UBC9-1", "uniprot_id": "SPRR3_HUMAN", "id": "Q9UBC9-1", "name": "Small proline-rich protein 3", "aln": "MSSYQQKQTFTPPPQLQQQQVKQPSQPPPQEIFVP-TTKEPCHSKVPQPGNTKIPEPGCTKVPEPGCTKVPEPGCTKVP-----------------------------------------------------------------------EPGCTKVPEPGCTKVPEPGCTKVPEPGYTKVPEPGS----IKVPDQGFIKFPEPGAIKVPEQGYTKVPVPGYTKLPEP--------CPSTVTPGPAQQKTKQK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "********.*..*** :*:*****.***** *** :*.****: ************ .******* * * **. *.:* **. *.: * *::*:***: ** * :. .**.* :* : *::: .** ***:*****:* * :*:*** **.**** *:******", "identical_positions": 102, "similar_positions": 36, "identity": "40.32%" }, { "cls_id": "homologset.agr.MGI:1330238", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z325-1", "uniprot_id": "DPM2_RAT", "id": "Q9Z325-1", "name": "Dolichol phosphate-mannose biosynthesis regulatory protein", "aln": "MATGTDQAVGFGLVAVSLIIFTYYTTWVILLPF--IDSQHVIHKYFLPRAYAVLLPLAAGLLLLLFVGLFITYVLLKSQKVTKKAQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z324-1", "uniprot_id": "DPM2_MOUSE", "id": "Q9Z324-1", "name": "Dolichol phosphate-mannose biosynthesis regulatory protein", "aln": "MATGTDQAVGFGLVAVSLIIFTYYTTWVILLPF--IDSQHVIHKYFLPRAYAVLLPLAAGLLLLLFVGLFITYVMLKSQKITKKAQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O94777-1", "uniprot_id": "DPM2_HUMAN", "id": "O94777-1", "name": "Dolichol phosphate-mannose biosynthesis regulatory protein", "aln": "MATGTDQVVGLGLVAVSLIIFTYYTAWVILLPF--IDSQHVIHKYFLPRAYAVAIPLAAGLLLLLFVGLFISYVMLKTKRVTKKAQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E1JIA5-1", "uniprot_id": "E1JIA5_DROME", "id": "E1JIA5-1", "name": "Dolichol phosphate-mannose biosynthesis regulatory protein", "aln": "MAS--NAQLGKIILISAIAVFFYYFFWVAVLPFMLIDEGNPIRLFFPPLKYAFIVPTVFGVIFLGGIAAFSFYHIWS-LRVKRD--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**: : :* :: :: :* ** ** :*** **. : *: :* * **. :* . *:::* :. * * : . ::.:. ", "identical_positions": 23, "similar_positions": 28, "identity": "26.74%" }, { "cls_id": "homologset.agr.MGI:1330239", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A8N1-1", "uniprot_id": "D4A8N1_RAT", "id": "D4A8N1-1", "name": "Dolichol-phosphate mannosyltransferase subunit 1", "aln": "MASTGASRSLAASQRPPQGRSSRQDKYSVLLPTYNERENLP-LIVWLLVKSFSESAINYEIIIIDDGSPDGTREVAEQLEKIYGPDRILLRPREKKLGLGTAYIHGIKHATGNYVIIMDADLSHHPKFIPEFIRKQKEGNFDIVSGTRYK-GNGGVYGWDLKRKIISRGANFITQILLRPGASDLTGSFRLYRKEVLQKLIEKCVSKGYVFQMEMIVR---ARQMDYTVGEVPISFVDRVYGESKLGGNEIVSFLKGLLTLFATT-----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70152-1", "uniprot_id": "DPM1_MOUSE", "id": "O70152-1", "name": "Dolichol-phosphate mannosyltransferase subunit 1", "aln": "MASTGASRSLAASPRPPQGRSSRQDKYSVLLPTYNERENLP-LIVWLLVKSFSESAINYEIIIIDDGSPDGTREVAEQLAEIYGPDRILLRPREKKLGLGTAYIHGIKHATGNYVIIMDADLSHHPKFIPEFIRKQKEGNFDIVSGTRYK-GNGGVYGWDLKRKIISRGANFITQILLRPGASDLTGSFRLYRKEVLQKLIEKCVSKGYVFQMEMIVR---ARQMNYTIGEVPISFVDRVYGESKLGGNEIVSFLKGLLTLFATT-----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60762-1", "uniprot_id": "DPM1_HUMAN", "id": "O60762-1", "name": "Dolichol-phosphate mannosyltransferase subunit 1", "aln": "MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLP-LIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRILLRPREKKLGLGTAYIHGMKHATGNYIIIMDADLSHHPKFIPEFIRKQKEGNFDIVSGTRYK-GNGGVYGWDLKRKIISRGANFLTQILLRPGASDLTGSFRLYRKEVLEKLIEKCVSKGYVFQMEMIVR---ARQLNYTIGEVPISFVDRVYGESKLGGNEIVSFLKGLLTLFATT-----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VIU7-1", "uniprot_id": "DPM1_DROME", "id": "Q9VIU7-1", "name": "Dolichol-phosphate mannosyltransferase subunit 1", "aln": "MPTNG-------------------HKYSILMPTYNEKDNLP-IIIWLIVKYMKASGLEYEVIVIDDGSPDGTLDVAKDLQKIYGEDKIVLRPRGSKLGLGTAYIHGIKHATGDFIVIIDADLSHHPKFIPEFIKLQQEGNYDIVSGTRYA-GNGGVFGWDFKRKLISRGANFLSQVLLRPNASDLTGSFRLYKKDVLEKCIASCVSKGYVFQMEMLVR---ARQHGYTIAEVPITFVDRIYGTSKLGGTEIIQFAKNLLYLFATT-----------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P14020-1", "uniprot_id": "DPM1_YEAST", "id": "P14020-1", "name": "Dolichol-phosphate mannosyltransferase", "aln": "----------------------MSIEYSVIVPAYHEKLNIKPLTTRLFAGMSPEMAKKTELIFVDDNSQDGSVEEVDALAHQGYNVRIIVRTNER--GLSSAVLKGFYEAKGQYLVCMDADLQHPPETVPKLFESLHDHAFTLG--TRYAPGVGIDKDWPMYRRVISSTARMMARPLT-IASDPMSGFFGLQKKYLENCNPRDINSQGFKIALELLAKLPLPRDPRVAIGEVPFTFGVRTEGESKLSGKVIIQYLQQLKELYVFKFGANNLILFITFWSILFFYVCYQLYHLVF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :**:::*:*:*: *: : *:. . : *:*.:**.* **: : .. * . :*::*.. **.:* ::*: .*.*:::: :****.* *: :*:::. :: : : *** * * .* : *::** *.:::: * :. ::* * * :* : : . *:*: : :*::.: .*: ::.***::* * * ***.*. *:.: : * *:. . ", "identical_positions": 62, "similar_positions": 91, "identity": "21.09%" }, { "cls_id": "homologset.agr.MGI:1330262", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AUQ7-1", "uniprot_id": "A0A8I6AUQ7_RAT", "id": "A0A8I6AUQ7-1", "name": "Zinc finger protein ZPR1", "aln": "MSASGA---VQPGPPGAAVGPSPTAAALSDTGPLFRPLSAEDEEQQPTEIESLCMNCYRNGTTRLLLTKIPFFREIIVSSFSCEHCGWNNTEIQSAGRIQDQGVRYTLTVKGQEDMNREVVKTDSATTRIPELDFEIPAFSQKGALTTVEGLISRAILGLEQDQPTRRAMEGAIAERIDEFIGKLKDLKQMAS---PFTLIIDDPSGNSFVEN-PHAPQKDSALVITYYDRTPQQAEMLGLQAEAPEEK-----------------------------SEE----EDLRNEVLQFNTNCPECNAPAQTNMKLVPNPHFKEVIIMATNCERCGHRTNEVKSGGAVEPLGTRITLHITDPSDMTRDLLKSETCSVEIPELEFELGMAVLGGKFTTLEGLLKDIRELVTKNPFTLG-DSSNPDQSEKLQEFSQKLGQIIEGKMKAHFIMNDPAGNSYLQNVYAPEDDPE--MKVERYKRSFDQNEELGLNDMKTEGYEADLAPQR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q62384-1", "uniprot_id": "ZPR1_MOUSE", "id": "Q62384-1", "name": "Zinc finger protein ZPR1", "aln": "MSASGA---VQPGHPGAAVGPSPAAAASPATGPLFRPLSAEDEEQQPTEIESLCMNCYRNGTTRLLLTKIPFFREIIVSSFSCEHCGWNNTEIQSAGRIQDQGVRYTLTVRSQEDMNREVVKTDSATTRIPELDFEIPAFSQKGALTTVEGLISRAISGLEQDQPTRRAVEGAIAERIDEFIGKLKDLKQMAS---PFTLVIDDPSGNSFVEN-PHAPQKDNALVITYYDRTPQQAEMLGLQAEAPEEK-----------------------------AEE----EDLRNEVLQFNTNCPECNAPAQTNMKLVQIPHFKEVIIMATNCENCGHRTNEVKSGGAVEPLGTRITLHITDPSDMTRDLLKSETCSVEIPELEFELGMAVLGGKFTTLEGLLKDIRELVTKNPFTLG-DSSNPDQSEKLQEFSQKLGQIIEGKMKAHFIMNDPAGNSYLQNVYAPEDDPE--MKVERYKRTFDQNEELGLNDMKTEGYEAGLAPQR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75312-1", "uniprot_id": "ZPR1_HUMAN", "id": "O75312-1", "name": "Zinc finger protein ZPR1", "aln": "MAASGA---VEPGPPGAAVAPSPAPAPPPAPDHLFRPISAEDEEQQPTEIESLCMNCYCNGMTRLLLTKIPFFREIIVSSFSCEHCGWNNTEIQSAGRIQDQGVRYTLSVRALEDMNREVVKTDSAATRIPELDFEIPAFSQKGALTTVEGLITRAISGLEQDQPARRANKDATAERIDEFIVKLKELKQVAS---PFTLIIDDPSGNSFVEN-PHAPQKDDALVITHYNRTRQQEEMLGLQEEAPAEK-----------------------------PEE----EDLRNEVLQFSTNCPECNAPAQTNMKLVQIPHFKEVIIMATNCENCGHRTNEVKSGGAVEPLGTRITLHITDASDMTRDLLKSETCSVEIPELEFELGMAVLGGKFTTLEGLLKDIRELVTKNPFTLG-DSSNPGQTERLQEFSQKMDQIIEGNMKAHFIMDDPAGNSYLQNVYAPEDDPE--MKVERYKRTFDQNEELGLNDMKTEGYEAGLAPQR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W379-1", "uniprot_id": "ZPR1_DROME", "id": "Q9W379-1", "name": "Zinc finger protein ZPR1", "aln": "MSTVSD---PNSSNP-------PESAGNIRPEPIFREINAEQTD-EIVEVESACMNCFETGVTRLLPTKIPFFREVVLMSFKCDHCGHINNEMQSASEIQKSGIRIELRVQSVADLNRRVVRSDNSSISIPEIELEIPVQSQKGEVTTVEGIIERTIAGLSQDQEKRRIDHPETAASIEKYIERLHRLKEVTT---PFQVLLEDISGNSFIEN-PLAPAADPQLKTSYFTRSQQQNEQLGLYEQNHEEQHLLK-----------------------PIAEDSWPIENLHGEVLQFPTNCPSCQAPCETNMKLTNIPHFKEVVIMATVCGACGHKTNEVKSGGGVEAQGVRFRVQIASREDLTRDVLKSETCSMSIPELDLEVGPHALCGRFTTVEGLLVAMRDQLDGTLFH---DSADDATKQQMQRFLDTFEDVMNLKRVITLVLEDPAGNTYVQSLSDDDSEPDDKLTVERYDRSYEDNEDLGLNDMKTEGYEEKA----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53303-1", "uniprot_id": "ZPR1_YEAST", "id": "P53303-1", "name": "Zinc finger chaperone ZPR1", "aln": "MSEQKEDLFKPVGEAAAEVEDESIAEQNKANDGVKLTGAQDAMGHPVQEIESLCMNCGKNGTTRLLLTSIPYFREIIIMSFDCPHCGFKNCEIQPASQIQEKGSRYVLKVECREDFNRQVIKSETATCKFVELDIEIPAK--RGQLTTVEGLLSEMIDDLSQDQEMRKSIDEALYKKIDDFIQKVKSYINCEPNTIPITFILDDPAGNSWIEYKPGEPQ--HKWSHTQYVRTDEQNVQVGIITRDQLEQRRQEQLKQLANRERNPSESVKVGSANPQFLSDATDIENFNNEVQTFRASCPSCTQECETHMKPVNIPHFKEVIIMSTVCDHCGYKSNEVKTGGAIPDKGRRITLYCDDAADLSRDILKSETCSMVIPELHLDIQEGTLGGRFTTLEGLLRQVYEELESRIFTQTSDSMDEATKARWVEFFAKLKEAIAGKVKFTVIMEDPLAGSYIQNVYAPDPDPN--MTIEDYERTKEQNEDLGLSDIKVE----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: . . . . : : *:** **** .* **** *.**:***::: **.* *** * *:*.*..**..* * * *. *:**.*::::.:: : *:::***. :* :*****:: . * .*.*** *: . *:.:* ::: : . *: .:::* :***::* * * : : *: :* :*: . *: .: *::..** * :.**.* .:*:** . ******:**:* * **:::****:**.: * *: : . *::**:*******: ****.::: .* *:***:**** : : : * ** : . : .* .: : : : .:::** ..:*:*.: : :*: :.:* *.*: ::**:***.*:*.* ", "identical_positions": 142, "similar_positions": 140, "identity": "28.29%" }, { "cls_id": "homologset.agr.MGI:1330275", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6XKD3-1", "uniprot_id": "PD2R2_RAT", "id": "Q6XKD3-1", "name": "Prostaglandin D2 receptor 2", "aln": "-MANITLKPLCPLLEEMVQLPNHSNSSLRYIDHVSVLLHGLASLLGLVENGLILFVVGCRMRQTVVTTWVLHLALSDLLAAASLPFFTYFLAVGHSWELGTTFCKLHSSVFFLNMFASGFLLSAISLDRCLQVVRPVWAQNHRTVAAAHRVCLMLWALAVLNTVPYFVFRDTIPRRDGRIMCYYNMLLLNPGSDRDTTCDYRQKALAVSKFLLAFMVPLAIIASSHVAVSLQLHHRGRQRTGRFVRLVAAIVVAFILCWGPYHIFSLLEARAHSVTTLRQLASRGLPFVTSLAFFNSVVNPLLYVLTCPDMLHKLRRSLLTVLESVLVEDSDLSTGPGKRCRRRHRRRASSTTTPASTLLLADRFPQLR-PARLIGWMRRGSAELPRRVREQSQEKQGSLSCTLD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z2J6-1", "uniprot_id": "PD2R2_MOUSE", "id": "Q9Z2J6-1", "name": "Prostaglandin D2 receptor 2", "aln": "-MANVTLKPLCPLLEEMVQLPNHSNSSLRYIDHVSVLLHGLASLLGLVENGLILFVVGCRMRQTVVTTWVLHLALSDLLAAASLPFFTYFLAVGHSWELGTTFCKLHSSVFFLNMFASGFLLSAISLDRCLQVVRPVWAQNHRTVAVAHRVCLMLWALAVLNTIPYFVFRDTIPRLDGRIMCYYNLLLWNPGPDRDTTCDYRQKALAVSKFLLAFMVPLAIIASSHVAVSLRLHHRGRQRTGRFVRLVAAIVVAFVLCWGPYHIFSLLEARAHSVTTLRQLASRGLPFVTSLAFFNSVVNPLLYVFTCPDMLYKLRRSLRAVLESVLVEDSDQSGG-----LRNRRRRASSTATPASTLLLADRIPQLR-PTRLIGWMRRGSAEVPQRV----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y5Y4-1", "uniprot_id": "PD2R2_HUMAN", "id": "Q9Y5Y4-1", "name": "Prostaglandin D2 receptor 2", "aln": "MSANATLKPLCPILEQMSRLQSHSNTSIRYIDHAAVLLHGLASLLGLVENGVILFVVGCRMRQTVVTTWVLHLALSDLLASASLPFFTYFLAVGHSWELGTTFCKLHSSIFFLNMFASGFLLSAISLDRCLQVVRPVWAQNHRTVAAAHKVCLVLWALAVLNTVPYFVFRDTISRLDGRIMCYYNVLLLNPGPDRDATCNSRQVALAVSKFLLAFLVPLAIIASSHAAVSLRLQHRGRRRPGRFVRLVAAVVAAFALCWGPYHVFSLLEARAHANPGLRPLVWRGLPFVTSLAFFNSVANPVLYVLTCPDMLRKLRRSLRTVLESVLVDDSELGGAG-----SSRRRRTSSTARSASPLALCSRPEEPRGPARLLGWLLGSCAASPQTG-----PLNRALSSTSS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** *******:**:* :* .***:*:*****.:****************:****************************:****************************:************************************.**:***:*********:*********.* *********:** ***.***:**: ** ***********:**********.****:*:****:*.*********:*.** *******:*********: . ** *. ***************.**:***:****** ****** :*******:**: . . :***:***: .**.* *..* : * *:**:**: ..* *: ", "identical_positions": 297, "similar_positions": 54, "identity": "73.33%" }, { "cls_id": "homologset.agr.MGI:1330276", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P61201-1", "uniprot_id": "CSN2_HUMAN", "id": "P61201-1", "name": "COP9 signalosome complex subunit 2", "aln": "MSDMEDDFMCDDEEDYDLEYSEDSNSEPNVDLENQYYNSKALKEDDPKAALSSFQKVLELE-GEKGEWGFKALKQMIKINFKLTNFPEMMNRYKQLLTYIRSAVTRNYSEKSINSILDYISTSKQMDLLQEFYETTLEALKDAKNDRLWFKTNTKLGKLYLEREEYGKLQKILRQLHQSCQTDDGEDDLKKGTQLLEIYALEIQMYTAQKNNKKLKALYEQSLHIKSAIPHPLIMGVIRECGGKMHLREGEFEKAHTDFFEAFKNYDESGSPRRTTCLKYLVLANMLMKSGINPFDSQEAKPYKNDPEILAMTNLVSAYQNNDITEFEKILKTNHSNIMDDPFIREHIEELLRNIRTQVLIKLIKPYTRIHIPFISKELNIDVADVESLLVQCILDNTIHGRIDQVNQLLELDHQKRGGARYTALDKWTNQLNSLNQAVVSKLA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P61202-1", "uniprot_id": "CSN2_MOUSE", "id": "P61202-1", "name": "COP9 signalosome complex subunit 2", "aln": "MSDMEDDFMCDDEEDYDLEYSEDSNSEPNVDLENQYYNSKALKEDDPKAALSSFQKVLELE-GEKGEWGFKALKQMIKINFKLTNFPEMMNRYKQLLTYIRSAVTRNYSEKSINSILDYISTSKQMDLLQEFYETTLEALKDAKNDRLWFKTNTKLGKLYLEREEYGKLQKILRQLHQSCQTDDGEDDLKKGTQLLEIYALEIQMYTAQKNNKKLKALYEQSLHIKSAIPHPLIMGVIRECGGKMHLREGEFEKAHTDFFEAFKNYDESGSPRRTTCLKYLVLANMLMKSGINPFDSQEAKPYKNDPEILAMTNLVSAYQNNDITEFEKILKTNHSNIMDDPFIREHIEELLRNIRTQVLIKLIKPYTRIHIPFISKELNIDVADVESLLVQCILDNTIHGRIDQVNQLLELDHQKRGGARYTALDKWTNQLNSLNQAVVSKLA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P61203-1", "uniprot_id": "CSN2_RAT", "id": "P61203-1", "name": "COP9 signalosome complex subunit 2", "aln": "MSDMEDDFMCDDEEDYDLEYSEDSNSEPNVDLENQYYNSKALKEDDPKAALSSFQKVLELE-GEKGEWGFKALKQMIKINFKLTNFPEMMNRYKQLLTYIRSAVTRNYSEKSINSILDYISTSKQMDLLQEFYETTLEALKDAKNDRLWFKTNTKLGKLYLEREEYGKLQKILRQLHQSCQTDDGEDDLKKGTQLLEIYALEIQMYTAQKNNKKLKALYEQSLHIKSAIPHPLIMGVIRECGGKMHLREGEFEKAHTDFFEAFKNYDESGSPRRTTCLKYLVLANMLMKSGINPFDSQEAKPYKNDPEILAMTNLVSAYQNNDITEFEKILKTNHSNIMDDPFIREHIEELLRNIRTQVLIKLIKPYTRIHIPFISKELNIDVADVESLLVQCILDNTIHGRIDQVNQLLELDHQKRGGARYTALDKWTNQLNSLNQAVVSKLA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6IQT4-1", "uniprot_id": "CSN2_DANRE", "id": "Q6IQT4-1", "name": "COP9 signalosome complex subunit 2", "aln": "MSDMEDDFMCDDEEDYDLEYSEDSNSEPNVDLENQYYNSKALKEDDPKAALSSFQKVLELE-GEKGEWGFKALKQMIKINFKLTNFPEMMNRYKQLLTYIRSAVTRNYSEKSINSILDYISTSKQMDLLQEFYETTLEALKDAKNDRLWFKTNTKLGKLYLEREEFGKLQKILRQLHQSCQTDDGEDDLKKGTQLLEIYALEIQMYTAQKNNKKLKALYEQSLHIKSAIPHPLIMGVIRECGGKMHLREGEFEKAHTDFFEAFKNYDESGSPRRTTCLKYLVLANMLMKSGINPFDSQEAKPYKNDPEILAMTNLVSAYQNNDITEFEKILKTNHSNIMDDPFIREHIEELLRNIRTQVLIKLIKPYTRIHIPFISKELNIDVADVESLLVQCILDNTINGRIDQVNQLLELDHQKRGGARYTALDKWTNQLNSLNQAIVSKLA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q94899-1", "uniprot_id": "CSN2_DROME", "id": "Q94899-1", "name": "COP9 signalosome complex subunit 2", "aln": "MSDNDDDFMCDDDEDYGLEYSEDSNSEPDVDLENQYYNSKALKEEEPKAALASFQKVLDLENGEKGEWGFKALKQMIKINFRLCNYDEMMVRYKQLLTYIKSAVTRNHSEKSINSILDYISTSKNMALLQNFYETTLDALRDAKNDRLWFKTNTKLGKLYFDRSDFTKLQKILKQLHQSCQTDDGEDDLKKGTQLLEIYALEIQMYTVQKNNKKLKALYEQSLHIKSAIPHPLIMGVIRECGGKMHLREGEFEKAHTDFFEAFKNYDESGSPRRTTCLKYLVLANMLMKSGINPFDSQEAKPYKNDPEILAMTNLVNSYQNNDINEFETILRQHRSNIMADQFIREHIEDLLRNIRTQVLIKLIRPYKNIAIPFIANALNIEPAEVESLLVSCILDDTIKGRIDQVNQVLQLDKINSSASRYNALEKWSNQIQSLQFAVVQKMA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** :*******:***.***********:***************::*****:******:** *******************:* *: *** *********:******:****************:* ***:******:**:*******************::*.:: ******:*********************************.************************************************************************************************************.:******.***.**: ::**** * *******:**************:**..* ****:: ***: *:******.****:**:********:*:**: : ..:**.**:**:**::**: *:*.*:*", "identical_positions": 371, "similar_positions": 57, "identity": "83.56%" }, { "cls_id": "homologset.agr.MGI:1330279", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3LI63-1", "uniprot_id": "KR201_HUMAN", "id": "Q3LI63-1", "name": "Keratin-associated protein 20-1", "aln": "MIYYSNYYGG--YGYGGLG------CGYGCGYR-GYGCGYG-GYGGYGNGYYCPSCYGRYWSYGFY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3LI61-1", "uniprot_id": "KR202_HUMAN", "id": "Q3LI61-1", "name": "Keratin-associated protein 20-2", "aln": "MCYYSNYYGGLRYGYGVLGGGYGCGCGYGHGYG-GLGCGYGRGYGGYGYGCCRPSCYGRYWSCGFY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A087WQL6-1", "uniprot_id": "A0A087WQL6_MOUSE", "id": "A0A087WQL6-1", "name": "", "aln": "MCYYRGYYGGLGYGYGGLG------YGYGCGYGCGYGCGYG-GYGGYGYGCCRPLCCRRYY--GFY", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* ** .**** **** ** *** ** * ***** ****** * * * **: ***", "identical_positions": 38, "similar_positions": 2, "identity": "57.58%" }, { "cls_id": "homologset.agr.MGI:1330281", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LRS8-1", "uniprot_id": "CD2AP_RAT", "id": "F1LRS8-1", "name": "CD2-associated protein", "aln": "---MVDYIVEYDYDAVHDDELTIRVGEIIRNVKKLQEEGWLEGELNGR--RGMFPDNFVKEIKR-ETEPKDDN------------LPIKRERPGNVASLVQRISTYGLPAG--GIQPHPQTKAMKKKTKKRQCKVLFEYSPQNEDELELTVGDVIDVIEEVEEGWWSGTLNNKLGLFPSNFVKELESTDDGEMHDAQEESEVSLTGPTSPMPSPGNGSEPAPGSVTQPKKIRGVGFGDIFKEGSVKLRTRTSSSETEEKKSEKPLILQSLGSRTQNVEVTKP-----DIDGKIKAKEYCKTVFPYTGTNEDELTFREGEIIHLISKETGEAGWWKGELNGKEGVFPDNFAVQISELDKDFP--------------------------------------------------------KPKKPPPPAKGPAPK----PDPLAGEKKTFPLKAEDRDEKSLLEQKPSKPAAP-------------------------------------------------------QVPPKKPTPPTKANNLLRSP------------------------------------GTMYPKRPEKPVPPPPPTAKINGEVSTISSKIDTEPLSKPKLDPEQLPVR---------------------------PKSVDLDALVAR--NSKETDNVNFDDIASS-ENLLHLTANRPKMPGRRLPGRFNGGHSPTQ-------------------------------------------------------------SPEKTLKLPKDDDSGNIKP----------------------------------------------------------------------SEFKKDAGYSSKPS--LSAPSSASKVNTAAFLSPLELKAKVEADDGKKSSLDELR-------AQIIELLCIVDALKKDHGKELEKLRRELEEEKAMRSNLEVEIAKLKKAVLLS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JLQ0-1", "uniprot_id": "CD2AP_MOUSE", "id": "Q9JLQ0-1", "name": "CD2-associated protein", "aln": "---MVDYIVEYDYDAVHDDELTIRVGEIIRNVKKLQEEGWLEGELNGR--RGMFPDNFVKEIKR-ETEPKDDN------------LPIKRERQGNVASLVQRISTYGLPAG--GIQPHPQTKAIKKKTKKRQCKVLFDYSPQNEDELELIVGDVIDVIEEVEEGWWSGTLNNKLGLFPSNFVKELESTEDGETHNAQEESEVPLTGPTSPLPSPGNGSEPAPGSVAQPKKIRGIGFGDIFKEGSVKLRTRTSSSETEEKKTEKPLILQPLGSRTQNVEVTKP-----DVDGKIKAKEYCRTLFPYTGTNEDELTFREGEIIHLISKETGEAGWWKGELNGKEGVFPDNFAVQISELDKDFP--------------------------------------------------------KPKKPPPPAKGPAPK----PDLSAAEKKAFPLKAEEKDEKSLLEQKPSKPAAP-------------------------------------------------------QVPPKKPTAPTKASNLLRSP------------------------------------GAVYPKRPEKPVPPPPPAAKINGEVSIISSKIDTEPVSKPKLDPEQLPVR---------------------------PKSVDLDAFVAR--NSKETDDVNFDDIASS-ENLLHLTANRPKMPGRRLPGRFNGGHSPTQ-------------------------------------------------------------SPEKTLKLPKEDDSGNLKP----------------------------------------------------------------------LEFKKDASYSSKSS--LSTPSSASKVNTAAFLTPLELKAKAEADDGKRNSVDELR-------AQIIELLCIVDALKKDHGKELEKLRKELEEEKAMRSNLEVEIAKLKKAVLLS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y5K6-1", "uniprot_id": "CD2AP_HUMAN", "id": "Q9Y5K6-1", "name": "CD2-associated protein", "aln": "---MVDYIVEYDYDAVHDDELTIRVGEIIRNVKKLQEEGWLEGELNGR--RGMFPDNFVKEIKR-ETEFKDDS------------LPIKRERHGNVASLVQRISTYGLPAG--GIQPHPQTKNIKKKTKKRQCKVLFEYIPQNEDELELKVGDIIDINEEVEEGWWSGTLNNKLGLFPSNFVKELEVTDDGETHEAQDDSETVLAGPTSPIPSLGNVSETASGSVTQPKKIRGIGFGDIFKEGSVKLRTRTSSSETEEKKPEKPLILQSLGPKTQSVEITKT-----DTEGKIKAKEYCRTLFAYEGTNEDELTFKEGEIIHLISKETGEAGWWRGELNGKEGVFPDNFAVQINELDKDFP--------------------------------------------------------KPKKPPPPAKAPAPK----PELIAAEKKYFSLKPEEKDEKSTLEQKPSKPAAP-------------------------------------------------------QVPPKKPTPPTKASNLLRSS------------------------------------GTVYPKRPEKPVPPPPPIAKINGEVSSISSKFETEPVSKLKLDSEQLPLR---------------------------PKSVDFDSLTVR--TSKETDVVNFDDIASS-ENLLHLTANRPKMPGRRLPGRFNGGHSPTH-------------------------------------------------------------SPEKILKLPKEEDSANLKP----------------------------------------------------------------------SELKKDTCYSPKPSVYLSTPSSASKANTTAFLTPLEIKAKVETDDVKKNSLDELR-------AQIIELLCIVEALKKDHGKELEKLRKDLEEEKTMRSNLEMEIEKLKKAVLSS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1R1N9-1", "uniprot_id": "F1R1N9_DANRE", "id": "F1R1N9-1", "name": "CD2-associated protein", "aln": "---MVEVVVEYEYEALHEDELTLRLGDIIKNVRRIEEEGWMEGDLNGK--RGLFPDNFVKEVRKDEPKSKEESKEPKEAKEVKEESTIQRRASGNVASLVQRISTYGIPAGGIGLQPHSQPRASKKKLKKRQCKVLFEYVPQNEDELELKVGEIIEITEEVEEGWWSGSMNGKSGLFPSNFVKEIDSTEDAENSDVTEEQDTRDGTSSPTSPHPGN------GVMAQPKKIKGIGFGDIFREGSVKLRTSLKGPSENMEKTEKPIPPLPSATKPTPLSTPEHPKGEKEAESKAKVKEYCKATFHYEATNQDELDLKEGEVILILSKDTGEPGWWRGEVNGKQGVFPDNFVSLLPESDKETLTSKGSIKVLSKQ----------------------------------------EPEERPKKPPPPSKSTVLK----PETPSVDKKQPQPRPEDKVVKPLPE-KPAKPAGP-------------------------------------------------------IVPPKKPVPPSKS--LLRP--------------------------------------SYHTKRPDLPLTPSPAAKQVQ---------NGDVPLSRRKSECEPVPIK---------------------------PKTV--VDIGEK--STETVNLMSFDDVSSSSEKLSHPTAQRPKMPGKRPP--AHRGHSPSKD---------------------------------------------------------VGEKAEKTEKIDEVETAPSPAP----------------------------------------------------------------------APAPAPSTQNSIKMPISSPLPSTTPKTISATLITPEPKPKPDKEQEKTSELEELK-------DQIKDLVLSVELLKTQQSRELGELRKELDDERLKRVALQMEIDKLKKICVQST", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KI34-1", "uniprot_id": "A0A0B4KI34_DROME", "id": "A0A0B4KI34-1", "name": "", "aln": "MENNICAIVEYEYAAKEPDELDLQKGAIIHRIKQMPG-GWWQGTLKASGVTGMFPDNFVRVLES----------------------GVSSNGNGTTG------SGDHIEVG------TAVQLRDKSATSNRRCKVIYSYTQVNDDELTLAVGDVIEFLGEVEEGWWRGRLRSKVGVFPSNFVQHIEPSP-VLASKRPPTIGATVTTSALTSKAANVANVAATATVPTGGAVPPASTSISTSTTKQATKSRATAAAAASAPAEPAAIVSGSGAAAGGGAAAAVP-----MLPPKPQREFCRVEFPYAPQNDDELELKVDDIIAVISTELPDKGWWKGEIRGKVGVFPDNFVKMLAPSEATAAPPLPRPRPRTRPGMGGTGAGSGSGIIDGVRTPRRTQRGGSFEFLGARMASFITTIFAPINEPPSATQITQNQRKVSNTASTTSHMTTTNSSNSSTTSVTTQQQKEQIGGSSSTTSKVYIKKTGSSSNSTTSSTTTASSSAGRKESFGSRDSLNDILSETGLPTGNVAAQRKSLENKNLDLTKPPGVGASVSIGQQRSSTSSATTSSATTVATGLTSSSVSKSMENMLDEKVKSPPPPVLSKKPSVPLKKTPTGGVPMTGNLLGGKKKNTEGKLTTAVSHDLADGLAASKMLSGANQLPESGAAGNVVIRRAATIAVEDTDFDRVERA-SILTDMRQGRVKAPKRRPPSAAINVLGESNNNSVYVNGSGMSGSGGAGSASELSEDGGAGGKTSDDNSTGEEPQLAKPKPREWEKKKAPWMEELKASQVTRKKTSPSVEPRGASVAERTSKLFAAEQAVSSNSSSITTKVQSSAVTSSMFVENSTTSSSVITSSSHTTTNDAIMSRSLSAAKVQTASSDEETRATRPNSLAIRNQRSVSPLVKSSNASSSQSQEEKPTSQLNNHQDASSSRVAQLEQRVDKLEGLVLNQQRTIEELVNALKSEAERVKILRSELDKYAQCVTQV-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :***:* * . *** :: * **:.:::: ** :* *:. *:******: :. :. . *... * : .* . *. .:*:***::.* *:*** * **::*:. ******* * :..* *:******:.:: : . . .: . . . :. : . . . :: ... .* . .. . . :*:*:. * * *:*** :: .::* ::*.: : ***:**:.** *******. : : * : **.:. . : .: : .: ...: .. : : . *..:: .* * :. : : .*.*. . : *:: : . *:: . : : .: .** : : . * . * * * :* * . :: . * :: . . : . * : . .. . . . :. : . : ... . :: ..::: : *: : : :: * :: : : :* . *..* *. *: * : ", "identical_positions": 108, "similar_positions": 195, "identity": "10.98%" }, { "cls_id": "homologset.agr.MGI:1330282", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P05942-1", "uniprot_id": "S10A4_RAT", "id": "P05942-1", "name": "Protein S100-A4", "aln": "MARPLEEALDVIVSTFHKYSGNEGDKFKLNKTELKELLTRELPSFLGRRTDEAAFQKLMNNLDSNRDNEVDFQEYCVFLSCIAMMCNEFFEGCPDKEPRKK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P07091-1", "uniprot_id": "S10A4_MOUSE", "id": "P07091-1", "name": "Protein S100-A4", "aln": "MARPLEEALDVIVSTFHKYSGKEGDKFKLNKTELKELLTRELPSFLGKRTDEAAFQKVMSNLDSNRDNEVDFQEYCVFLSCIAMMCNEFFEGCPDKEPRKK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P26447-1", "uniprot_id": "S10A4_HUMAN", "id": "P26447-1", "name": "Protein S100-A4", "aln": "MACPLEKALDVMVSTFHKYSGKEGDKFKLNKSELKELLTRELPSFLGKRTDEAAFQKLMSNLDSNRDNEVDFQEYCVFLSCIAMMCNEFFEGFPDKQPRKK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** ***:****:*********:*********:***************:*********:*.******************************** ***:****", "identical_positions": 91, "similar_positions": 8, "identity": "90.1%" }, { "cls_id": "homologset.agr.MGI:1330284", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q08268-1", "uniprot_id": "MCH4_YEAST", "id": "Q08268-1", "name": "Probable transporter MCH4", "aln": "----------------------------------------------------------------------------------------------------------------MLNIPIIANSKRFLFSKDHEAQSTRDHDVELETRE--GPSSGYNPNFNAADAILKKNSDQ-VDLDVN-KLTNVTSRVLNTPEAS-LIYDDDREFPDGGLKAWLVVFGAFMGLVPVFGLINSLGAIESYISKH-QLANISSSTISWIFSLYLAISFLSCILSGGYFDRNGSIGLMCTGTVIYAGGLFALANCKSVWQFILAFSVCSGLGTGILMTPLIGTVATWFLKRRGIATSISTMGGSIGGIVFPIMLRKLY-------KEVGFQWAIRILSFICLTCLICASVLARER--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TKPVVQPFKSKAE----------------------------------------------------------------------------------------------------VAKW------YISSVFNWRYFLEGKFLFVAIGASFAESSLTSCATYLASYSMTRGNTENVAYTMITASNAVGILGRYIPGYFAD-KFIGRFNVEIITISMAALFNFVMWLPFGGNTKVLWAYVCLWGFSTGSILSLTPVCIGQISKTTDFGKRYATVYLLQALVTIPVLPIGGTLIGKGTVAN-YNHFIIFNSALMAAGAACYIISRHICVGAKLCKF----------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q08777-1", "uniprot_id": "MCH5_YEAST", "id": "Q08777-1", "name": "Riboflavin transporter MCH5", "aln": "----------------------------------------------------------------------------------------------------------MSSDSLTPKDTIVPEEQTNQLRQPDLDEDSIHYDPEADDLESLETTASYASTSVSAKVYTKKEVNKGTDIESQPHWGENTSSTHDSDKEE-DSNEEIESFPEGGFKAWVVTFGCFLGLIACFGLLNSTGVIESHLQDN-QLSSESVSTIGWLFSLFLFVCSASCIISGTYFDRNGFRTIMIVGTVFHVAGLFATANSTKYWHFILSFAIVCGFGNGIVLSPLVSVPAHYFFKRRGTALAMATIGGSVGGVVFPIMLRSFFSMKSDTDPTYGFVWGIRTLGFLDLALLTLSIILVKER--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LPHVIE--NSKDG----------------------------------------------------------------------------------------------------ESRWRYILRVYILQCFDAKAFLDMKYLFCVLGTVFSELSINSALTYYGSYATSHGISANDAYTLIMIINVCGIPGRWVPGYLSD-KFG-RFNVAIATLLTLFIVMFVGWLPFGTNLTNMYVISALYGFCSGSVFSLLPVCCGQISKTEEFGKRYSTMYFVVGFGTLVGIPITGAIISIKTTAD-YQHYIIFCGLATFVSAVCYIISRAYCVGFKWVRF----------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "O70451-1", "uniprot_id": "MOT2_MOUSE", "id": "O70451-1", "name": "Monocarboxylate transporter 2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPSEP-----------------SAPLPQPLPPDGGWG-WVVVCASFISIGFSYAFPKAVTVFFKDIQ---EIFNTTSSQIAWISSIMLAVMYAGGPISSVLVNNYGSRPVVIVGGLLCCIGMILASYSNSVIELYLTVGFIGGLGLAFNLQPALTIIGKYFYRRRPLANGCAMAGSPVFLSTLAPFNQYLFN-------NYGWKGSFLILGGIFLHSCVAGCLMRPVG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PSPNTKKSKSK-----------------------------------------------------------------------------------------VGSRHD--STLKKASKVSTAQKVNRFLDFSLFMHRGFLIYLSGNVILFLGIFAPIIFLAQYAKHIGVDDYNSAFLLSVMAFIDMFARPSVGLIANTSLIRPRIQYLFSSAIIFTGICHLLCPLATTYSALVVYVVFFGLGFGSISSLLFECLMDIVGATRFSSAVGLTTIVECCPVLFGPPLAGKLL--DITGE-YKYLYIASGTVVLVSGTYLLIGNAINYRLLDKERKREKAKKKKSASHASREMEALNRSKQ-DEVTVKASNAHNPPSDRDKESNI--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63344-1", "uniprot_id": "MOT2_RAT", "id": "Q63344-1", "name": "Monocarboxylate transporter 2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPSESSVKAT------------AAPPPFPLPPDGGWG-WVVVCASFISIGFSYAFPKAVTVFFNDIK---DIFKTTSSQIAWISSIMLAVMYAGGPISSVLVNNYGSRPVVIVGGLLCCTGMILASFSSSVIELYLTVGFIGGLGLAFNLQPALTIIGKYFYRKRPLANGFAMAGSPVFLSTLAPFNQFLFN-------SYGWKGSFLILGAIFLHSCVAGCLMRPVG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PSPRAAKSKSK-----------------------------------------------------------------------------------------VGSRQD--SSTKRLSKVSTAEKINRFLDFGLFTHRGFLIYLSGNVVLFLGMFAPIIFLAPYAKDKGVDDYNSAFLLSVMAFTDMFARPSVGLIANTSLIRPRIQYLFSVAIMFTGICHLLCPLAHSYTALVVYVIFFGIGFGSISSLLFECLMDQVGASRFSSAVGLVTIVECCPVLFGPPLAGKLL--DITGQ-YKYLYIASGIVVLSSGIYLLICNAINYRLLEKERKREKARRKKSASQASKEMEALSRSKQ-DDVTVKVSNTHNPPSDRDKESSI--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O60669-1", "uniprot_id": "MOT2_HUMAN", "id": "O60669-1", "name": "Monocarboxylate transporter 2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPPMP-----------------SAPPVHP-PPDGGWG-WIVVGAAFISIGFSYAFPKAVTVFFKEIQ---QIFHTTYSEIAWISSIMLAVMYAGGPVSSVLVNKYGSRPVVIAGGLLCCLGMVLASFSSSVVQLYLTMGFITGLGLAFNLQPALTIIGKYFYRKRPMANGLAMAGSPVFLSSLAPFNQYLFN-------TFGWKGSFLILGSLLLNACVAGSLMRPLG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PNQTTSKSKNK-----------------------------------------------------------------------------------------TGKTEDDSSPKKIKTKKSTWEKVNKYLDFSLFKHRGFLIYLSGNVIMFLGFFAPIIFLAPYAKDQGIDEYSAAFLLSVMAFVDMFARPSVGLIANSKYIRPRIQYFFSFAIMFNGVCHLLCPLAQDYTSLVLYAVFFGLGFGSVSSVLFETLMDLVGAPRFSSAVGLVTIVECGPVLLGPPLAGKLV--DLTGE-YKYMYMSCGAIVVAASVWLLIGNAINYRLLAKERKEENARQK------TRESEPLSKSKHSEDVNVKVSNAQSVTSER--ETNI--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W509-1", "uniprot_id": "Q9W509_DROME", "id": "Q9W509-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------MVHG---PPARRKSQQQ-------HEACEMDMERQP------------------------TPPDGGWG-WVVVFGSFMIHIVTDGMTYSFGIFYNEFL---DYFNEGKGYTAWIASIMVGVTFSSGPISSSFVNRYGCRAVTIAGSILAASCIIVSMFAQNVLTLIITIGFGTGLGFGLIYLPAIVSVTQYFEAKRSLATGIAVCGSGFGTFVFAPLTEFLIG-------NYGWRGAMLIIGGIVLNCIIFGAMFRPL----------------------------------------ELEAPPQTPPNTPSTPKLAKKSAIIDQNTTAAELEPLKVLP---------------------KDQYLQLPQRTDTAVSGGALCRS----NSVGHNLKPNLNNNSN----------GAVNGQGPTLVT------------PPQAVVKSTSNDDIARKCHSQLQLTPLRDAHRE----RSASGTMYRP----DALYQGSLHNLPDYVSS------RNDLSRSMSGSGVIKRYGSLRQSNNVSQSQEEAKCCGCITCSKETRDTFAEMMNFSLLKDMVFVIFSVSNFCTSIGFNVPYLYVVAYAETLKLTKTDASYLISTIGVANTVGRIILGYISDKPWVNR--LLVYNVCLTACGVSTAMVPLCHDFQSLAFYCCVFGFTIGAYVGLTSVILVDLLGLDKLTNAFGLLLLFQGIASFIGPPIGGWMY--DLTDS-YAPAFLMAGLMIAISGLVMFAIPPLQRLQVRKSERKPHTEHLALS-----------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W0L6-1", "uniprot_id": "Q9W0L6_DROME", "id": "Q9W0L6-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------MVDTNSSNPGIVGGNSASSARLRRFERTDSELACEEAARLTAEQSPEDEDNQDNDEDDDDEE-SVYGELPPPPDGGYG-WVICFASFMCNMIVDGIAYTFGIFLEEFV---AYFHEGKGTVAWVGSLLSGVYLSAGPIVSALANKYGCRAVCIAGSIIACIAFVLSTFSTNVSMLMATYGFMGGFGFGMIYLPAVVAVGYYFETKRSLATGIAVCGSGFGTFAFAPLATYLLE-------EYGWKNALLIFAGLILNCAIFGAMMRPLTYPKKKKQKPLMQRMYEEKQLQLERGSFAGSHFMVQLPDGTIERKLKMPLNADPGVHSSLNLELLAQQAGGGGLHPVSTLPTITESKVVDVHRQNGAQSPPNGDSNGQLSARSAAGAVGRRPHRNSESENSPYHSQDAMTRNASQPAFLAGDHQSLPKNGSVPAFNTRVRKTSASERFQPSLAAIRATSRGDLEAGAGGDFASSKLSLSQRQGGSQTGSSGRMVRPMSRKDIFYSGSVTNLPQYQSQKSLANYRNSVLSLTKYEKSMQSVAKLDPLAEAEKHREEYDLCPCLGIPDSVKSVVNTMLDVSLLKDPVFMLIGVSNIFGMAGLYVPFVYLVDAAKEHDIPKNDAAMLLSIIGITNTVGRVFCGWVADLPQVNS--LLLNNCCLLVSTIAVTLTPLCYSYAAYITMSIFFGLAISGYISLTSIILVDLLGLDKLTNAFGLLILFRGFAALIGTPLAGAIY--DMTHT-YDLPFYMAGALFGISTITSFLAPCLKRCSPSE-ETPVHVETLTPIDEEQGEDAEDDEDQPITIVPKIIKTLASPQQEEGHPQFPQKTSESKL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36032-1", "uniprot_id": "MCH2_YEAST", "id": "P36032-1", "name": "Probable transporter MCH2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------MSEERHEDHHRDVENKLNLNGKDDINGNT--------------------SISIEVPDGGYG-WFILLAFILYNFSTWGANSGYAIYLAHYLENNTFAGGSKLDYASIGGLAFSCGLFFAPVITWLYHIFSIQFIIGLGILFQGAALLLAAFSVTLWEIYLTQGVLIGFGLAFIFIPSVTLIPLWFRNKRSLASGIGTAGSGLGGIVFNLGMQSILQ-------KRGVKWALIAQCIICTSLSTIALMLTRTT-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HQGLRQHKRSYKFELLDYDVLSNFAVWLLFGFVSFAMLGYVVLLYSLSDFTVSLGYTSKQGSYVSCMVSVGSLLGRPIVGHIADKYGSLTVGMILH---LVMAILCWAMWIPCKNLATAIAFGLLVGSIMGTIWPTIASIVTRIVGLQKLPGTFGSTWIFMAAFALVAPIIGLELRSTDTNGNDYYRTAIFVGFAYFGVSLCQWLLRGFIIARDEIAVREAYSADQNELHLNVKLSHMSKCLFRYKQLPRRV------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P53918-1", "uniprot_id": "ESBP6_YEAST", "id": "P53918-1", "name": "Uncharacterized transporter ESBP6", "aln": "MSTHSNDYFSASSGMVSETSSEVSSINSSQPVSFSKASIAAPVPCSDLHSTKSNDASRKLSISRTLTNRLNDIKKAVDDDNLQTEENSADVNKILESRFDVADAIRLQHNESVQSKLNIPVTHTTTAGASLSAPSSSAFSASSIQNDTTEHKASMDSKLMRNRLYPASTKHSGKDLEAQGITEFEPDEPTVKKVFTNKSTGQLELPPDGGYG-WVVTFCVFLTMFSTWGCNASFGVDLAYYLNHDTYPGASKYDYALIAGLTVFLGQLLSPLVMALMRIIGLRTTMLFGDAVMLAAYLLASFTTKLWQLYVTQGFMVGCSISLIFVPATTVLPGWFLKKRAVAMGVSLLGTGAGGVVYGLATNKMLS------DFGNTRWCLRIIGISCSISVLVAIALLKER---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NPTPAIG----------------------------------------------------------------------------------------------------------LKSPRAMFEQLKAMFSLKVITKPFVVLIALWFMFALFAYNMMVFTLSSYAISKGLSSHDASTLTAILNGSQSIGRPLMGLAGDKFGRANVTIVLT---TLLTIYMFAFWIPAHTFVQLIFFSILVGSCVGVANVMNTVLIADMVKPEEFLPAWAFVNYCGAPFLLVCEVIAQALTVEKDKSNPYLHAQIFCGCCFIAALILISILREYSIRMKLTERQAMTNEKLKEWKASEYDTDSADEDWGKLKERKTKYDLLLGPGIKKYFLRMVYPMKV--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:** *.: :: . . : .: : . * . . . : : .. * . .: * :* :* * . . * : . : . : :. : . : . : . : .* * .: . . * . : . : : : * . ", "identical_positions": 15, "similar_positions": 52, "identity": "1.55%" }, { "cls_id": "homologset.agr.MGI:1330288", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0M606-1", "uniprot_id": "A0ABK0M606_RAT", "id": "A0ABK0M606-1", "name": "Hyaluronidase", "aln": "MEYLEAIFTPPSPALLHFLRRARREALMAVLAVQKAACLWPWTLSPYPLFPAGSHLCGMITQLGLTLVVGLTLCLVHVQALLQVPE--------LPFSVLWNVPSARCKTRFGVHLPLDALGIIANHGQRFHGQNITIFYKNQFGLYPYFGPRGTAHNGGIPQAVSLDHHLAQAAHQILHNLGSSFAGLAVLDWEEWYPLWAGNWGTHRQVYQAASWAWAQQMFPDLNPQEQLHKAQTGFEQAARALMEHTLRLGQMLRPHGLWGFYRYPVCGNGWHNMASNYTGHCHPAIITRNTQLRWLWAASSALFPSIYLPPRLP-PAYHQTFVRHRLEEAFRVALTGH--AHPLPVLAYVRLTHRSSGRFLSL------------------------------EECWRLHDYLVGTLGPYVINVTKAATACSHQRCHGHGRCSWKDPGQMEAFLHLQPDD--NLGAWKS-FRCRCYLGWSGPTCLEPKP------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VEI3-1", "uniprot_id": "HYAL3_MOUSE", "id": "Q8VEI3-1", "name": "Hyaluronidase-3", "aln": "----------------------------------------------------------MIMHLGLMMVVGLTLCLMHGQALLQVPE--------HPFSVVWNVPSARCKAHFGVHLPLDALGIVANHGQHFHGQNISIFYKNQFGLYPYFGPRGTAHNGGIPQAVSLDHHLARAAHQILHSLGSSFAGLAVLDWEEWYPLWAGNWGPHRQVYLAASWVWTQQMFPGLDPQEQLHKAHTSFEQAARALMEYTLQLGRTLRPSGLWGFYRYPACGNGWHKMASNYTGHCHAAITTRNTQLRWLWAASSALFPSIYLPPRLP-LAYRQAFVRHRLEEAFRVALLEH--SHPLPVLAYSRLTHRSSGRFLSLDDLMQTIGVSAALGTAGVVLWGDLSFSSSEEKCWRLHDYLVGTLGPYVINVTKAAMACSHQRCHGHGRCARKDPGQMEAFLHLQPDD--SLGAWNS-FRCHCYSGWAGPTCLEPKP------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43820-1", "uniprot_id": "HYAL3_HUMAN", "id": "O43820-1", "name": "Hyaluronidase-3", "aln": "----------------------------------------------------------MTTQLGPALVLGVALCLGCGQPLPQVPE--------RPFSVLWNVPSAHCEARFGVHLPLNALGIIANRGQHFHGQNMTIFYKNQLGLYPYFGPRGTAHNGGIPQALPLDRHLALAAYQIHHSLRPGFAGPAVLDWEEWCPLWAGNWG-RRRAYQAASWAWAQQVFPDLDPQEQLYKAYTGFEQAARALMEDTLRVAQALRPHGLWGFYHYPACGNGWHSMASNYTGRCHAATLARNTQLHWLWAASSALFPSIYLPPRLP-PAHHQAFVRHRLEEAFRVALVGH--RHPLPVLAYVRLTHRRSGRFLSQDDLVQSIGVSAALGAAGVVLWGDLSLSSSEEECWHLHDYLVDTLGPYVINVTRAAMACSHQRCHGHGRCARRDPGQMEAFLHLWPDG--SLGDWKS-FSCHCYWGWAGPTCQEPRPGPKEAV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NJV4-1", "uniprot_id": "A0A8M1NJV4_DANRE", "id": "A0A8M1NJV4-1", "name": "Hyaluronidase", "aln": "-------------------------------------------------------MLLESNVLHPFLTLALSIMLSPSNPFLNMVEGVESVIGRRGFQVIWNVPTARCQRRYGVSLPLQQYNIIHNSHQRFQGQNMSIFYQRRLGLYPYISREGVKVNGGLPQEGYLKAHLSLAGVEIREKLRSSFSGLAVLDWEAWEPVWKWNFG-TRIVYRKLSKKLVRWEHPDMSEEEVKSKAKLDFELAARQFMEETLRLGLRLCPEGLWGFYGFPSCYNNNGQGQSGYTGKCHNGTEILNDRLGFLWQQSTALYPSIYLWRKLAGHTHAQLMVRHRILEALRVASQHSPGSEPLPVFPYTRVAFIHSLTFLNQTDLEHTLGESAALGAAGVVLWGELSFAKSKHQCTLLRDYLSSVLGEYITALRAGVTNCSERLCNAQGRCSRWDPHSHHMIPLLGPHDALSLSDMRSKFKCVCYEGWSGEKCEHRIS------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :.:.::: * :.: :: * *.*:****:*:*: ::** ***: .*: * *:*:***::***:.::*****:. .*. ***:** *. **: *. :* ..* ..*:* ****** * *:* *:* * .* * .: .*.:. :* ** .** *** :** **::. * * ****** :* * *. . *.***:** . * :* :** *:**:***** :*. :: * :****: **:*** .****:.* *::. * **. .:* *:*** ..** *: : .. **.: *:.:***: ** . . : * *.. .*. .* * * ** **:* .* . . ", "identical_positions": 149, "similar_positions": 110, "identity": "30.41%" }, { "cls_id": "homologset.agr.MGI:1330290", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O14753-1", "uniprot_id": "OVOL1_HUMAN", "id": "O14753-1", "name": "Putative transcription factor Ovo-like 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPRAFLVKKPCVSTCKRN--WSELPDEERGEIYVP---------------------------------------------VSLGFCPPQPYREP-EPSVAEPPSCP---LALNMSLRDSS--------------------YSMAPGPCV-VAQLPS-EDMGHLTDPQ---------------------------------------------SRDHGFLRTKMKVTLGDSP---------------------------------------------------SGDLFTCRVCQKAFTYQRMLNRHMKCHNDVKRHLCTYCGKGFNDTFDLKRHVRTHTGVRPYKCSLCDKAFTQRCSLESHLKKIHGVQQKYAYKERRAKLYVCEECGCTSESQEGHVLHLKEHHPDSPLLR-KTSKKVAVALQNTVTSLLQ-GSPHL---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9WTJ2-1", "uniprot_id": "OVOL1_MOUSE", "id": "Q9WTJ2-1", "name": "Putative transcription factor Ovo-like 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPRAFLVKKPCVSTCKRN--WSELPDEERGEIYVP---------------------------------------------VSLGFCPPQPYREP-EASVAEPPSCP---LALDMSLRDSS--------------------YSVAPGPCV-VAQLPS-EDVSHLTDPQ---------------------------------------------SRDQGFLRTKMKVTLGDSP---------------------------------------------------NGDLFTCHICQKSFTHQRMLNRHMKCHNDVKRHLCTYCGKGFNDTFDLKRHVRTHTGVRPYKCSLCDKAFTQRCSLESHLKKIHGVQQKYAYKERRAKLYVCEECGCTSESQEGHVLHLKERHPDSPLLR-KTSKKVAVALQNTVTSLLQ-GSPHL---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A445-1", "uniprot_id": "D4A445_RAT", "id": "D4A445-1", "name": "Putative transcription factor Ovo-like 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPRAFLVKKPCVSTCKRN--WSELPDEERGEIYVP---------------------------------------------VSLGFCPPQPYLEP-EASVAEPPSCP---LALDMSLRDSS--------------------YGVASGPCE-VAQLPP-EDVNHLTDPQ---------------------------------------------SRDQGFLRTKMKVTLGDSP---------------------------------------------------NGDLFTCHICQKSFTYQRMLNRHMKCHNDVKRHLCTYCGKGFNDTFDLKRHVRTHTGVRPYKCSLCDKAFTQRCSLESHLKKIHGVQQKYAYKERRAKLYVCEECGCTSESQEGHVLHLKEHHPDSPLLR-KTSKKVAVALQNTVTSLLQ-GSPHL---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F8W4G4-1", "uniprot_id": "F8W4G4_DANRE", "id": "F8W4G4-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPRAFLVKKTGNSPGKRN--WSDLPDHERGDIYIP---------------------------------------------VSM---SPFAYREETEASPAEVPLCLSKRKDRNMYTHSQM--------------------YTNDPGAVVPVAELPSCTALGQSPETEHIRS-----------------------------------------TQNNTYVRTKIKVTTGELPTEAPPVVPSVTTSPPVSIATHCSPPVTKPLM-----------------VQSSGATYVCQVCQKVFQFQRMLNRHLKCHSEQKRHLCDFCGKGFNDTFDLKRHVRTHTGVRPYKCELCDKAFTQRCSLESHMKKIHGVTQQYAYKERRSKLYVCEECGHTASTQDALLRHLHTEHPNSAFLRAKGARRHSPSLNGTKDDTSQPGSPLSLNSDDNAES", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P51521-1", "uniprot_id": "OVO_DROME", "id": "P51521-1", "name": "Transcriptional regulator ovo", "aln": "MPKIFLIKNRLHQQQQRLLESQNLLQHKNQDDERLVPPLSPSGSGSGPSPTPTSQPPPEPQGQGQQVLGQVPDSDQQPLSLTRKRFHHRRHYFGQSRHSLDHLNQNQSPNPNANANPNQIQNPAELEVECATGQVQNENFAAELLQRLTPNTATTAQNNIVNNLVNNSRAATSVLATKDCTIENSPISIPKNQRAEDEEEQEDQEKEKPAEREREKSDERTEQVEKEERVEREEEEDDEVDVGVEAPRPRFYNTGVVLTQAQRKEYPQEPKDLSLTIAKSSPASPHIHSDSESDSDSDGGCKLIVDEKPPLPVIKPLSLRLRSTPPPADQRPSPPPPRDPAPAVRCSVIQRAPQSQLPTSRAGFLLPPLDQLGPEQQEPIDYHVPKRRSPSYDSDEELNARRLERARQVREARRRSTILAARVLLAQSQRLNPRLVRSLPGILAAAAGHGRNSSSSSGAAGQGFQSSGFGSQNSGSGSSSGNQNAGSGAGSPGSGAGGGGGMGGGRDGRGNYGPNSPPTGALPPFYESLKSGQQSTASNNTGQSPGANHSHFNANPANFLQNAAAAAYIMSAGSGGGGCTGNGGGGASGPGGGPSANSGGGGGGGGGNGYINCGGVGGPNNSLDGNNLLNFASVSNYNESNSKFHNHHHHHQHNNNNNNNGGQTSMMGHPFYGGNPSAYGIILKDEPDIEYDEAKIDIGTFAQNIIQATMGSSGQFNASAYEDAIMSDLASSGQCPNGAVDPLQFTATLMLSSQTDHLLEQLSDAVDLSSFLQRSCVDDEESTSPRQDFELVSTPSLTPDSVTPVEQHNTNTTQLDVLHENLLTQLTHNIVRGGSNQQQQHHQQHGVQQQQQQQHSVQQQQQHNVQQQHGVQQQHVQQQPPPSYQHATRGLMMQQQPQHGGYQQQAAIMSQQQQQLLSQQQQQSHHQQQQQQQHAAAYQQHNIYAQQQQQQQQQHHQQQQQQQHHHFHHQQQQQPQPQSHHSHHHGHGHDNSNMSLPSPTAAAAAAAAAAAAAAAAAAH-LQRPMSSSSSSGGTNSSNSSGGSSNSPLLDANAAAAAAAALLDTKPLIQSLGLPPDLQLEFVNGGHGIKNPLAVENAHGGHHRIRNIDCIDDLSKHGHHSQHQQQQGSPQQQNMQQSVQQQSVQQQQSLQQQQQQQHHQHHSNSSASSNASSHGSAEALCMGSSGGANEDSSSGNNKFVCRVCMKTFSLQRLLNRHMKCHSDIKRYLCTFCGKGFNDTFDLKRHTRTHTGVRPYKCNLCEKSFTQRCSLESHCQKVHSVQHQYAYKERRAKMYVCEECGHTTCEPEVHYLHLKNNHPFSPALLKFYDKRHFKFTNSQFANNLLGQLPMPVHN------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :* :: * ::: .. . :: :** .: .* . .: * . . * .. ... : * :. .: : :: : ::: : : . .. :.*::* * * **:****:***.: **:** :**************.***********.**:*:********** :*:*.* ::*******:*:******* *: : **: .** *. * :: :. . * ", "identical_positions": 89, "similar_positions": 74, "identity": "6.55%" }, { "cls_id": "homologset.agr.MGI:1330292", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JU41-1", "uniprot_id": "A0A0G2JU41_RAT", "id": "A0A0G2JU41-1", "name": "Dual specificity tyrosine-phosphorylation-regulated kinase 4", "aln": "-MQLLPLPALTWTETKMDTNKARKRSLTTFPVLKARKKQSFTSVKVESKPLVQLQKPSSKTKKLRSNRCSQKNPSTSSSAFPFVDTKGKKNTVNFPHIGNKTLPKGSTLYQEN---QIHNQLLSSELKTSEIPFSFSTKAQDTKVQDTKLHPELPKRHKVPLTAAEALKFFKNQLSPYEQSEILGYSELWFLGLDAKKLNVVPEKFSKTS---FDDEHGSYVKVLHDHIAYRYEVLDMIGKGSFGQVAKCLDHKNNELVALKIIRNKKRFHHQALVELKILEALRRKDKDNTHNVVHMKDFFYFRNHLCITFELLGINLYELMKNNSFQGFSLSIVRRFTLSVLKCLQMLYVEKIIHCDLKPENIVLYHRGQVTVKVIDFGSSCYEHQKVYTYIQSRFYRSPEVILGHPYNMAIDMWSLGCIMAELYTGYPLFPGENEVEQLACIMEVLGLPPTHLIQTATRRQIFFDSKGLPKNITNNRGEKRYPNSKDLPMVVKTYDSSFLDFLRRCLVWEPSLRMTPDQALKHAWIHEPRKFKPWPRPQIQRKPGVSSSSETSKD-------------------------------------------KTEEHQASKGTKDEATKETTDKLKDEPEKHPES-------------------------------------------------------------SCKRQSSIQHLANTVQLPNLAEASGKPEAVAGSETSEEQQCTS---SPKSTNILPPIM----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BI55-1", "uniprot_id": "DYRK4_MOUSE", "id": "Q8BI55-1", "name": "Dual specificity tyrosine-phosphorylation-regulated kinase 4", "aln": "-MQLLRLPALTRTETSMDTNKARKRSLTTFPILKARKKQSFTSVKVESKPLGHLQKPSSKNKKLRVNRCPQKIP--SNTAFPFVDTKGKRNTVNFPQIGNKVPSKGPMQYQEN---QIHNQVLSSELKTSEIPFNINTKAQDTKP-----HPELQKKHKVPLTVAEALKFFKNQLSPYEQSEILGYSELWFLGLEAKKLNVVPEKFSKTS---FDDEHGSYMKVLHDHIAYRYEVLEMIGKGSFGQVAKCLDHKNNELVALKIIRNKKRFHHQALVELKILEALRRKDKDNNHNVVHMKDFFYFRNHLCITFELLGINLYELMKNNSFHGFNLSIVRRFTFSILKCLHMLYVEKIIHCDLKPENIVLYQRGQVTVKVIDFGSSCYEHQKVYTYIQSRFYRSPEVILGHPYNMAIDMWSLGCIMAELYTGYPLFPGENEVEQLACIMEVLGLPPAHFTQTASRRQVFFDSKGLPKNINNNRGGKRYPDSKDLTMVVKTYDSSFLDFLRRCLVWEPSLRMTPEQALKHAWIHEPRKFKPRPKPQILRKPGASISSEISTE-------------------------------------------KAEEQQASKGKKDEATKETTDKLKDEAEKHLEN-------------------------------------------------------------SGKQQSSVEHTADTIQLPHLTEASGKSETVAGSEMSAEQQSTS---SPKSTNILPPIV----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NR20-1", "uniprot_id": "DYRK4_HUMAN", "id": "Q9NR20-1", "name": "Dual specificity tyrosine-phosphorylation-regulated kinase 4", "aln": "-------------------------------------------------------------------------------------------------------------------------MPASELKASEIPFHPSIKTQDPKAE-----EKSPKKQKVTLTAAEALKLFKNQLSPYEQSEILGYAELWFLGLEAKKLDTAPEKFSKTS---FDDEHGFYLKVLHDHIAYRYEVLETIGKGSFGQVAKCLDHKNNELVALKIIRNKKRFHQQALMELKILEALRKKDKDNTYNVVHMKDFFYFRNHFCITFELLGINLYELMKNNNFQGFSLSIVRRFTLSVLKCLQMLSVEKIIHCDLKPENIVLYQKGQASVKVIDFGSSCYEHQKVYTYIQSRFYRSPEVILGHPYDVAIDMWSLGCITAELYTGYPLFPGENEVEQLACIMEVLGLPPAGFIQTASRRQTFFDSKGFPKNITNNRGKKRYPDSKDLTMVLKTYDTSFLDFLRRCLVWEPSLRMTPDQALKHAWIHQSRNLKPQPRPQTLRKSNSFFPSETRKD-------------------------------------------KVQGCHHSSRKADEITKETTEKTKDSPTKHVQH-------------------------------------------------------------SGDQQDCLQHGADTVQLPQLVDAPKKSEAAVGAEVSMTSPGQSKNFSLKNTNVLPPIV----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B7V3-1", "uniprot_id": "A0ACD6B7V3_DANRE", "id": "A0ACD6B7V3-1", "name": "dual-specificity kinase", "aln": "MVGEGTTPSCCGFEILQKCWGTRQSHRNRRVQPKSARPEAFPHPHRAQADNTKIGPNCTYTQKCGTGVGTLPQLEAPVKQVLVTNGKLLHSNGTLPSIVKQLVQSTQGNQEERPRPQFPNRFGSSVENLSES-LTRSIINKFEKIR-------TYEGQRLPMSPTTALKHFQNQLTEYEREEIMDYSEIWYLGLDTKKIEGSQGSPQNAG---YDDEHGSYLKVLHDHIGYRYEVLEVIGKGSFGQVLKCLDHKTNETVAIKIIRNKKRFHHQALVELKILDAVRRRDRDNCHNVIHMKEYFYFRNHLCISFELLGANLYELIKKNNFQGFSLGLIRRFAHSLLKCLQMLHKEKIIHCDLKPENILLSQRGQGNIKVVDFGSSCYEQQRVYTYIQSRFYRSPEVILGHPYSMAIDMWSLGCILAELYTGYPLFPGESEVEQIACIMEIMGLPPNDFVQTASRRRLFFDSKGNPRNITNSKGKKHRPSSKDLASVLKTNDPLFLDFIQRCLVWDPTKRMTPDEAMQHEWITEGRLNRLHPKPRPLRKESDNNYEFTYRK-------------------------------------------ATGNRTADKSGSDEKLKRVSDASSKGGKTVSEERLRP-------------------------------------------------------IGASAEEENSENSSKSLSKDSKTDSSGERSVQIIIKPQTGSSSDSSSSEGPEPQFLPPIV----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V3D5-1", "uniprot_id": "DYRK2_DROME", "id": "Q9V3D5-1", "name": "Dual specificity tyrosine-phosphorylation-regulated kinase 2", "aln": "--------MLDRCEMPIQLDNEKLRRDVRLSGSRLDLPQLCNGSRRLDGHNNHVAANENTVTTTSLNGNG--------------NGNGNSNSNNNNNIGSPVSSSTTNSSNGG------NERGSSTKSNSSSGSGSSGNSASSTGS-------GELKCNTPMTPSELVKKFRNYLTDLEFEELKVYKEVWYFGQHASKNYNKPAPTANTTNLGYDDDNGNYKIIEHDHIAFRYEILEVIGKGSFGQVIRALDHKTNTHVAIKIIRNKKRFLNQAVVELNILDELREKDADGSHNVIHMLDYTYFRKHLCITFELMSLNLYELIKKNNYNGFSMSLIRRFCNSIVKCLRLLYKENIIHCDLKPENILLKQRGSSSIKVIDFGSSCYVDRKIYTYIQSRFYRSPEVILGLQYGTAIDMWSLGCILAELYTGFPLFPGENEVEQLACIMEVLGLPPKVLISVARRRRLFFDSRDAPRCITNTKGRKRSPGSKSLAHILHCQDRYFIDFLQRCLEWDPAERMTPDEAAHHEFLQPSASSRHRSCRMSSSSSSSGLNSVSQKSSCYSFSEISPGTNGPVVASITSTTAVHNAAIATTTKSRQQPPSQSHGHAQSNGHLPDIKLSASDKYNSMQKVAVRSKITSSVSDLESVQQYSLHRIYGGVGSGSTHHVSSAATRKHLPGTGSGIVGAMSSKYGSSTLAHNHHNVTHHNASTATIATTTHHHHHHGGQQQQQSSSGASTMAMSHSQSTGDVSDRAIFGRA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* . *. . . . .:: : :* *:* *: * .*: * *:*::* .:.* :: :**::* * : ****.:***:*: ********* :.****.* **:********* :**::**:**: :*.:* *. :**:** :: ***:*:**:***:. *****:*:*.::**.:.::*** *::***::* *:***********:* ::*. .:**:******* .:::***************** *. ********** ******:******.****:*****::**** : ..* **: ****:. *: *.*.:* *: *.**.*. ::: * *:**::*** *:*: ****::* :* :: : . . . . . .. : .:: .. . : ... .: :.: .. . : . : . :. : ", "identical_positions": 196, "similar_positions": 146, "identity": "25.89%" }, { "cls_id": "homologset.agr.MGI:1330293", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LFN2-1", "uniprot_id": "A0ABK0LFN2_RAT", "id": "A0ABK0LFN2-1", "name": "", "aln": "MYYTDFEGSVFPGCYWGSYGYPLGYSVGCGYGSTYSPVGYGLGYGYNGCGAY--RRYWPFALY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O08633-1", "uniprot_id": "KRA81_MOUSE", "id": "O08633-1", "name": "Keratin-associated protein 8-1", "aln": "MYYTGAEGSVFPGCYWGSYGYPLGYSVGCGYGSTYSPVGYGLGYGYNGCGAY--RRYWPFALY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IUC2-1", "uniprot_id": "KRA81_HUMAN", "id": "Q8IUC2-1", "name": "Keratin-associated protein 8-1", "aln": "MLCDNFPGAVFPGCYWGSYGYPLGYSVGCGYGSTYSPVGYGFGYGYNGCGAFGYRRYSPFALY", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . *:********************************:*********: *** *****", "identical_positions": 51, "similar_positions": 4, "identity": "80.95%" }, { "cls_id": "homologset.agr.MGI:1330294", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99020-1", "uniprot_id": "ROAA_MOUSE", "id": "Q99020-1", "name": "Heterogeneous nuclear ribonucleoprotein A/B", "aln": "-------------------MSDAAEEQPMETTGATENGHEAAPEGEAPVEPSAAAAAPAASAGSGGGTTTAPSGNQNGAEGDQINASKNEE-----------------------------------------------------------------DAGKMFVGGLSWDTSKKDLKDYFTKFGEVVDCTIKMDPNTGRSRGFGFILFKDSSSVEKVLDQKEHRLDGRVIDPKKAMAMKKDPVK-KIFVGGLNPEA-TEEKIREYFGQFGEIEAIELPIDPKLNKRRGFVFITFKEEDPVKKVLEKKFHTVSGSKCEIKVAQPKEVYQQQ--------------QYGSGGRGNRN-----RGNRGSGGG--------------------------------------------------------------------------------------------------------------------------------------------QGSTNYGKSQRRGG----HQNNYKPY--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99729-1", "uniprot_id": "ROAA_HUMAN", "id": "Q99729-1", "name": "Heterogeneous nuclear ribonucleoprotein A/B", "aln": "-------------------MSEAGEEQPMETTGATENGHEAVP------EASRGRGWTGAAAGAGGATAAPPSGNQNGAEGDQINASKNEE-----------------------------------------------------------------DAGKMFVGGLSWDTSKKDLKDYFTKFGEVVDCTIKMDPNTGRSRGFGFILFKDAASVEKVLDQKEHRLDGRVIDPKKAMAMKKDPVK-KIFVGGLNPESPTEEKIREYFGEFGEIEAIELPMDPKLNKRRGFVFITFKEEEPVKKVLEKKFHTVSGSKCEIKVAQPKEVYQQQ--------------QYGSGGRGNRN-----RGNRGSGGGGGGGGQSQSWNQGYGNYWNQGYGYQ-----------------------------------------------------------------------------QGYGPGYGGYDYSPYGYYG-----------YGPGYDYSQGSTNYGKSQRRGG----HQNNYKPY--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q08473-1", "uniprot_id": "SQD_DROME", "id": "Q08473-1", "name": "RNA-binding protein squid", "aln": "----------------------MAENKQVDTEINGEDFTKDVT-----------ADGPGSENGDAG-----AAGSTNGSSDNQSAASGQRD-----------------------------------------------------------------DDRKLFVGGLSWETTEKELRDHFGKYGEIESINVKTDPQTGRSRGFAFIVFTNTEAIDKVSAADEHIINSKKVDPKKAKARHG-----KIFVGGLTTEI-SDEEIKTYFGQFGNIVEVEMPFDKQKSQRKGFCFITFDSEQVVTDLLKTPKQKIAGKEVDVKRATPKPENQMMGGMRGGPRGGMRGGRGGYGGRGGYNNQWDGQGSYGGYGGGYGGYGAGGYGDYYAGGYYNGYDYG-----------------------------------------------------------------------------YDGYGYGGGFEGNGYGGGGGGNMGGGRGGPRGGGGPKGGGGFNGGKQRGGGG----RQQRHQPY--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q99383-1", "uniprot_id": "HRP1_YEAST", "id": "Q99383-1", "name": "Nuclear polyadenylated RNA-binding protein 4", "aln": "MSSDEEDFNDIYGDDKPTTTEEVKKEEEQNKAGSGTSQLDQLAALQALSSSLNKLNNPNSNNSSSNNSNQDTSSSKQDGTANDKEGSNEDTKNEKKQESATSANANANASSAGPSGLPWEQLQQTMSQFQQPSSQSPPQQQVTQTKEERSKADLSKESCKMFIGGLNWDTTEDNLREYFGKYGTVTDLKIMKDPATGRSRGFGFLSFEKPSSVDEVVKT-QHILDGKVIDPKRAIPRDEQDKTGKIFVGGIGPDV-RPKEFEEFFSQWGTIIDAQLMLDKDTGQSRGFGFVTYDSADAVDRVCQNKFIDFKDRKIEIKRAEPRHMQQKSSNNGGNNGGNNMNRRGGNFGNQGDFNQMYQNPMMGGYNPMMNPQAMTDYYQKMQEYYQQMQKQTGMDYTQMYQQQMQQMAMMMPGFAMPPNAMTLNQPQQDSNATQGSPAPSDSDNNKSNDVQTIGNTSNTDSGSPPLNLPNGPKGPSQYNDDHNSGYGYNRDRGDRDRNDRDRDYNHRSGGNHRRNGRGGRGGYNRRNNGYHPYNR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::: :. . . . . : . .. .:.. :.. :: .* : : *:*:***.*:*::.:*:::* *:* : . .: ** *******.*: * .. ::::* :* ::.: :***:* . . ******: .: :::. :*.::* * :: :* . .: :** *:*:.. : * : :. . . : ::* * *: * : * *. . . *. . *. : : : * ::: ::** ", "identical_positions": 55, "similar_positions": 105, "identity": "10.26%" }, { "cls_id": "homologset.agr.MGI:1330295", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O08632-1", "uniprot_id": "KR195_MOUSE", "id": "O08632-1", "name": "Keratin-associated protein 19-5", "aln": "MSYYGSYYG----GLGSGIRGFGNLGYGYGCGCG-FGGYGYGSGYGRYGYGYPRPLYYGGYGFSRFY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1LZR0-1", "uniprot_id": "F1LZR0_RAT", "id": "F1LZR0-1", "name": "", "aln": "MSYYGSYYGGYYGGLGSGYRGFGNLGYGYGCGCG-FGGHGYGSVYGRYGYGYRRPFYYGGYGFSRFY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3LI54-1", "uniprot_id": "KR198_HUMAN", "id": "Q3LI54-1", "name": "Keratin-associated protein 19-8", "aln": "MSYYRSYYG----GLGYGYGGFGGWGYGYGCGYGSFRRLGYGCGYGGYGFSCCRPLYYGGYGFSAFY", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**** **** *** * ***. ******* * * ***. ** **:. **:******** **", "identical_positions": 43, "similar_positions": 5, "identity": "64.18%" }, { "cls_id": "homologset.agr.MGI:1330299", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q13627-1", "uniprot_id": "DYR1A_HUMAN", "id": "Q13627-1", "name": "Dual specificity tyrosine-phosphorylation-regulated kinase 1A", "aln": "MHTGGETSACKPSSVRLAPSFSFHAAGLQMAGQMPHSHQYSDRRQPNIS----DQQVSALSYSDQIQQPLTNQVMPDIVMLQRRMPQTFRDPATAPLRKLSVDLIKTYKHINEVYYAKKKRRHQQGQGDD-SSHKKERKVYNDGYDDDNYDYIVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIPPAHILDQAPKARKFFEKLP-DGTWNLKKTKDGKREYKPPGTRKLHNILGVETGGPGGRRAGESGHTVADYLKFKDLILRMLDYDPKTRIQPYYALQHSFFKKTADEGTNTSNSVSTSPAME----------------------QSQSSGTTSSTSSSS----------GGSSGTSNSGRARSDPTHQHRHS----------------GGHFTAAVQAMDCETHSPQVRQQFPAPLGWSGTEAPTQVTVETHPVQET--TFHVAPQQNALHHHHGNSSHHHHHHHHHH---------HHHGQQALGN---------------------------------RTRPRVYN----------SPTNSSSTQDSMEVGHSHHSMTSLSSSTTSSSTSSSSTGNQGNQ-------AYQNRPVAANTLDFGQNG-------------AMDVNLTVYSNPRQETG------------IAGHPTYQF--SANTGPAHYMTEGHLTMRQGADREES----PMTGVCVQQSPVASS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q63470-1", "uniprot_id": "DYR1A_RAT", "id": "Q63470-1", "name": "Dual specificity tyrosine-phosphorylation-regulated kinase 1A", "aln": "MHTGGETSACKPSSVRLAPSFSFHAAGLQMAAQMPHSHQYSDRRQPNIS----DQQVSALSYSDQIQQPLTNQVMPDIVMLQRRMPQTFRDPATAPLRKLSVDLIKTYKHINEVYYAKKKRRHQQGQGDD-SSHKKERKVYNDGYDDDNYDYIVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIPPAHILDQAPKARKFFEKLP-DGTWSLKKTKDGKREYKPPGTRKLHNILGVETGGPGGRRAGESGHTVADYLKFKDLILRMLDYDPKTRIQPYYALQHSFFKKTADEGTNTSNSVSTSPAME----------------------QSQSSGTTSSTSSSS----------GGSSGTSNSGRARSDPTHQHRHS----------------GGHFAAAVQAMDCETHSPQVRQQFPAPLGWSGTEAPTQVTVETHPVQET--TFHVAPQQNALHHHHGNSSHHHHHHHHHH---------HHHGQQALGN---------------------------------RTRPRVYN----------SPTNSSSTQDSMEVGHSHHSMTSLSSSTTSSSTSSSSTGNQGNQ-------AYQNRPVAANTLDFGQNG-------------AMDVNLTVYSNPRQETG------------IAGHPTYQF--SANTGPAHYMTEGHLTMRQGADREES----PMTGVCVQQSPVASS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61214-1", "uniprot_id": "DYR1A_MOUSE", "id": "Q61214-1", "name": "Dual specificity tyrosine-phosphorylation-regulated kinase 1A", "aln": "MHTGGETSACKPSSVRLAPSFSFHAAGLQMAAQMPHSHQYSDRRQPSIS----DQQVSALPYSDQIQQPLTNQVMPDIVMLQRRMPQTFRDPATAPLRKLSVDLIKTYKHINEVYYAKKKRRHQQGQGDD-SSHKKERKVYNDGYDDDNYDYIVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIPPAHILDQAPKARKFFEKLP-DGTWSLKKTKDGKREYKPPGTRKLHNILGVETGGPGGRRAGESGHTVADYLKFKDLILRMLDYDPKTRIQPYYALQHSFFKKTADEGTNTSNSVSTSPAME----------------------QSQSSGTTSSTSSSS----------GGSSGTSNSGRARSDPTHQHRHS----------------GGHFAAAVQAMDCETHSPQVRQQFPAPLGWSGTEAPTQVTVETHPVQET--TFHVAPQQNALHHHHGNSSHHHHHHHHHH---------HHHGQQALGN---------------------------------RTRPRVYN----------SPTNSSSTQDSMEVGHSHHSMTSLSSSTTSSSTSSSSTGNQGNQ-------AYQNRPVAANTLDFGQNG-------------AMDVNLTVYSNPRQETG------------IAGHPTYQF--SANTGPAHYMTEGHLAMRQGADREES----PMTGVCVQQSPVASS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M2B3P5-1", "uniprot_id": "A0A8M2B3P5_DANRE", "id": "A0A8M2B3P5-1", "name": "dual-specificity kinase", "aln": "-----------------------------MAAPMPHSHQQYSDCHQQST----DQSVTVLPYSDQTQA---------LTASQRHMPQCFRDPTLAPLRKLSIDLIKTYKHINEVYYAKKKRRHQQGQGED-SSHKKERKVFNDGYDDENYDYVVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRAEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQLCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIPPNHIMDLAPKARKFFEKLS-DGTWSIKKTKDGKR-YKPPASRKLHAILGVECGGPGGRRAGESGHAVADYLKFKDLILRMLDYDPKTRIQPYYALQHSFFKKTTDEGTNTSSSVSTSPALE----------------------QSQSSGTTSSTSSSS----------GGSSGTSTSGRARSDPTHHHRHS----------------SGHFGTAMPAIDCDNLCPQARQPYHPPVVWPGIVGPEPVTVETHPVQET--TFHVPPQ-------HPKALHPHHHHHHHH---------HHHHGQVIAT---------------------------------RPRPRLYN----------SPTNSASTQDSMEVVHGHLSMTSLSSSASSSSTSSSSTGNHGNQ-------AYQLRHLPANTLDFSQNGSL-----------SMSMGLGAFSNPRQETG------------MAGNPTYPV--ATNTGTGHFIAEGHLGMRQGIDREDS----PMTGVCVQQSSMASS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P49657-1", "uniprot_id": "MNB_DROME", "id": "P49657-1", "name": "Serine/threonine-protein kinase minibrain", "aln": "MYRLEDTNSGGVMDKNKQKLSAYGSSGGSVDAAQGSGSGGGRQRHAPLYGRFVDAEDLPATHRDVMHHHSSPSSSSEVRAMQARIPNHFREPASGPLRKLSVDLIKTYKHINEVYYAKKKRRAQQTQGDDDSSNKKERKLYNDGYDDDNHDYIIKNGEKFLDRYEIDSLIGKGSFGQVVKAYDHEEQCHVAIKIIKNKKPFLNQAQIEVKLLEMMNRADAENKYYIVKLKRHFMWRNHLCLVFELLSYNLYDLLRNTNFRGVSLNLTRKFAQQLCTALLFLSTPELNIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYHYIQSRFYRSPEVLLGIQYDLAIDMWSLGCILVEMHTGEPLFSGCNEVDQMNKIVEVLGMPPKYLLDQAHKTRKFFDKIVADGSYVLKKNQNGRK-YKPPGSRKLHDILGVETGGPGGRRLDEPGHSVSDYLKFKDLILRMLDFDPKTRVTPYYALQHNFFKRTADEATNTSGAGATANAGAGGSGSSGAGGSSGGGVGGGLGASNSSSGAVSSSSAAAPTAATAAATAAGSSGSGSSVGGGSSAAQQQQAMPLPLPLPLPLPPLAGPGGASDGQCHGLLMHSVAANAMNNFSALSLQSNAHPPPSLANSHHSTNSLGSLNHISPGSTGCHNNNSNSSNNNTRHSRLYGSNMVNMVGHHNSGSSNNHNSISYPHAMECDPPQMPPPPPNGHGRMRVPAIMQLQPNSYAPNSVPYYGNMSSSSVAAAAAAAAAAASHLMMTDSSVISASAAGGGQGGGNPGQNPVTPSAAAFLFPSQPAGTLYGTALGSLSDLPLPMPLPMSVPLQLPPSSSSSVSSGSASVGSGGVGVGVVGQRRHITGPAAQVGISQSVGSGSSGSATGASSSDASSSSPMVGVCVQQNPVVIH", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . : * . .: * : : * ::*: **:*: .******:******************** ** **:* **:*****::******:*:**::*****::**********************: ** **********.*********:***:**: *:* *****:******:*********:****************************:*******:****.*************************************:***************: **************************.**************:** :::* * *:****:*: **:: :**.::*:: ****.:**** ***** ******* .*.**:*:**************:*****: *******.***:*:**.****.: :*: * ...***:.**:*::: .****:..* . *..::::: .* .: .. ..:. : : . .. * :: . *..:. *:.* : :: : : :* : : **: . : :*. * *.:. ::: : . .* **. * ::*:: .... ** *:: *: .*.** * :: : * *.. .:* :.*: : :::.* .: : .* * . .:: **.******..:. ", "identical_positions": 388, "similar_positions": 180, "identity": "42.68%" }, { "cls_id": "homologset.agr.MGI:1330300", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4V8A3-1", "uniprot_id": "DYRK3_RAT", "id": "Q4V8A3-1", "name": "Dual specificity tyrosine-phosphorylation-regulated kinase 3", "aln": "MGGAARERGRKDAALPGAGLPPQQRRLGDGVYDTFMMIDETKCPPYTNTLCNPSEAPVSRRLNITTEP-FTRGHTQHFVSGGVMKVEQLFQEFGSRRTS-----TLQSDGVSNS-------------------------EKSSP-------------ASQGKSSDSLGTVKCSLSSRPSKVL----------------------------PLTPEQALKQYKHHLTAYEKLEIISYPEIYFVGPNAKKRQGVIGGPNNGGYDDADGAYIHVPRDHLAYRYEVLKIIGKGSFGQVARVYDHKLRQYVALKMVRNEKRFHRQAAEEIRILEHLKKQDKTGSMNVIHMLESFTFRNHVCMAFELLSIDLYELIKKNKFQGFSVQLVRKFAQSILQSLDALHKNKIIHCDLKPENILLKHHGRSATKVIDFGSSCFEYQKLYTYIQSRFYRAPEIILGCRYSTPIDIWSFGCILAELLTGQPLFPGEDEGDQLACMMELLGMPPQKLLEQSKRAKYFINSKGLPRYCSVTTQTDGRVVLLGGRSRRGKKRGPPGSKDWAAALKGCDDYLFIEFLKRCLQWDPSARLTPAQALRHPWISKSAPRPLT----------------TDKVSGKR--------------------------------------------------------------------------VVNPTNAFQGLG------------SKLPPVVG-IAS-KLKANLMSETSGSIP--------------LCSVLPKLIS--------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q922Y0-1", "uniprot_id": "DYRK3_MOUSE", "id": "Q922Y0-1", "name": "Dual specificity tyrosine-phosphorylation-regulated kinase 3", "aln": "MGGAARDRGRKDAALPGAGLPPQQRRLGDGVYDTFMMIDETKGPPYSDTFSNPSEAPVSRRLNITTEP-LTRGHTQHFVNGSEMKVEQLFQEFGNRRSN-----TLQSDGISNS-------------------------EKSSP-------------ASQGKSSESLSAVKCNLSSRPSKVL----------------------------PLTPEQALKQYKHHLTAYEKLEIVSYPEIYFVGPNAKKRQGVIGGPNNGGYDDADGAYIHVPRDHLAYRYEVLKIIGKGSFGQVARVYDHKLRQYVALKMVRNEKRFHRQAAEEIRILEHLKKQDKTGSMNVIHMLESFTFRNHVCMAFELLSIDLYELIKKNKFQGFSVQLVRKFAQSILQSLDALHKNKIIHCDLKPENILLKHHGRSATKVIDFGSSCFEYQKLYTYIQSRFYRAPEIILGCRYSTPIDIWSFGCILAELLTGQPLFPGEDEGDQLACMIELLGMPPQKLLEQSKRAKYFINSKGLPRYCSVSTQTDGRVVLLGGRSRRGKKRGPPGSKDWATALKGCGDYLFIEFLKRCLQWDPSARLTPAQALRHPWISKSTPKPLT----------------MDKVPGKR--------------------------------------------------------------------------VVNPTNAFQGLG------------SKLPPVVG-IAS-KLKANLMSETSGSIP--------------LCSVLPKLIS--------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43781-1", "uniprot_id": "DYRK3_HUMAN", "id": "O43781-1", "name": "Dual specificity tyrosine-phosphorylation-regulated kinase 3", "aln": "MGGTARGPGRKDAGPPGAGLPPQQRRLGDGVYDTFMMIDETKCPPCSNVLCNPSEPPPPRRLNMTTEQ-FTGDHTQHFLDGGEMKVEQLFQEFGNRKSN-----TIQSDGISDS-------------------------EKCSPT------------VSQGKSSDCLNTVKSNSSSKAPKVV----------------------------PLTPEQALKQYKHHLTAYEKLEIINYPEIYFVGPNAKKRHGVIGGPNNGGYDDADGAYIHVPRDHLAYRYEVLKIIGKGSFGQVARVYDHKLRQYVALKMVRNEKRFHRQAAEEIRILEHLKKQDKTGSMNVIHMLESFTFRNHVCMAFELLSIDLYELIKKNKFQGFSVQLVRKFAQSILQSLDALHKNKIIHCDLKPENILLKHHGRSSTKVIDFGSSCFEYQKLYTYIQSRFYRAPEIILGSRYSTPIDIWSFGCILAELLTGQPLFPGEDEGDQLACMMELLGMPPPKLLEQSKRAKYFINSKGIPRYCSVTTQADGRVVLVGGRSRRGKKRGPPGSKDWGTALKGCDDYLFIEFLKRCLHWDPSARLTPAQALRHPWISKSVPRPLTT---------------IDKVSGKR--------------------------------------------------------------------------VVNPASAFQGLG------------SKLPPVVG-IAN-KLKANLMSETNGSIP--------------LCSVLPKLIS--------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB40EDC8-1", "uniprot_id": "A0AB40EDC8_DANRE", "id": "A0AB40EDC8-1", "name": "dual-specificity kinase", "aln": "MMILSRKPDG----------PVTAARHGDGLYDSYMRTDHIVNQDADVNGQSPSGLPPLPKHTGVIKP-TMKDH--QAIRGGQMKVKYVYEDSYNRKLNG----VSQHNGTSQVP------------------------AKPPPA------------ISKERSVDSNSSVKSSESSTKVTKLG--------------------------SPMTPEQALKQHRQQMTTLEQQEIHNYSEIYFLGPNAKKRQAVAGGTNNSGYDDDQGGYIHVPHDHLAYRYEFLKVIGKGSFGQVAKVYDHKLQQHVALKIVRNEKRFHRQAAEEIRILEHLKKQDKTGSMNVVHMLENFTFRNHICMTFELLSMNLYELIKRNKFQGFSLPLVRKFAHSILQCLEALHRHKIIHCDLKPENILLKQQGRSGIKVIDFGSSCFDHQRVYTYIQSRFYRAPEVILGSRYGMPIDMWSFGCILAELLTGYPLFPGEDEGDQLACMMELLGMPPSKLLEQAKRAKNFISSKGHPRYCTVSTLSNGTIVLNGSRSRRGKMRGAPGSKEWGTALKGCEDATFIDFLKKCLDWDPSTRMTPVQALRHPWLYKRLPKPAPGG--------------EKTVLPKR--------------------------------------------------------------------------ISEHSTSFPTII------------SKVPPVMG-STNNKLRTTMMGDSTGSIP--------------FRTVLPKLVS--------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P83102-1", "uniprot_id": "DYRK3_DROME", "id": "P83102-1", "name": "Putative dual specificity tyrosine-phosphorylation-regulated kinase 3 homolog", "aln": "MVGSQEKKNN---HIELSETPATDKNNLNTTHLENTQLSKALSPPTSLPQIQIQMINQNLTHTGIAQNNTEKANRHQYRDSGLQYLTRCFEPLAMLNDSKEDFPTQPSNNIANYPGDIQILPIFDCCEISESIQAISLPNVTSPSKTKDVPGLFLRTISENSKSKSEPECESLISVKESSVMENHTFLFHEQIIMSGQQKCELHEKPKVLVVSPQQVMILYMNKLTPYERTEILTYPQIYFIGANAKKRPGVYG-PNNSEYDNEQGAYIHVPHDHVAYRYEMLKIIGKGSFGQVIKAYDHKTHEHVALKIVRNEKRFHRQAQEEIRILHHLRRHDKYNTMNIIHMFDYFTFRNHTCITFELLSINLYELIKKNGFKGFSLQLVRKFAHSLLQCLDALYKNDIIHCDMKPENVLLKQQGRSGIKVIDFGSSCFENQRIYTYIQSRFYRAPEVILGGKYGRAIDMWSLGCILAELLSGHALFPGENESDQLACIIEVLGMPNKNILASSKRSKSFFSPKGYPRYCTVRTMSDGMVVLIGGQSRRGKQRGPPCSKSLSKALDGCKDPLFLNFIRGCLEWDADKRLTPSEALKHPWLRRRLPRPPSSSSGCGGVSGLCSSRNESPVTGQNRNFAAETTASSTSATSISLTIKRENSHSSLRLHHGAVPETDFKLIKSVPEGSSTATKEPMMNSDILPESFRQTTVVSPSKHSADSGGMSCLSAVDVGPSRYYPYMNNNENNRLFSSSLNSSANSLSHLEQATKLDALGEYSASTTPNLLSKNTGYSFNSGSINIDVAQESLVNIASNYALDKSIDIIGKSNVSLHTNKLKVQSKDM", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . . * . : : .. . . . : : : .. : :: . . . :. :: .* *: . .. :. * . : ::*:*.: : :::*. *: ** .*.:***:*.***** .* * .**. **: :*.*****:**:*****.**:********* :.**** :::****:*********** ******.**:::** .:**::**:: ****** *::*****::******:* *:***: ******:*:**.*:**:::.*****:****:***::***. **********: *::*************:*** :*. .**:**:********:* .*****:*.*****::*:**** ::* .:**:* *:..** ****:* * ::* :** *.:***** **.* **. . **.** * *::*:: **.**.. *:** :**:***: : *:* . . * :. : . :. *: * :. . :* :. :..: .*:. :. *:*:* ", "identical_positions": 247, "similar_positions": 169, "identity": "29.69%" }, { "cls_id": "homologset.agr.MGI:1330301", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LYY7-1", "uniprot_id": "F1LYY7_RAT", "id": "F1LYY7-1", "name": "Dual specificity tyrosine-phosphorylation-regulated kinase 2", "aln": "-----------MLTRKPSAAAPAAYPTGRGGDTAVRQLQASPG---------IGAGAPRSGVGTGPPSPIALPPLRAS------NATTTSHTIGGGKHTMNDHLHISH--SHGQIQVQQLFEDNSNKRTVLTTQPNGLTTVGKTG------LPVVPERQLESIHRRQGSSTSLKSMEGMG----------------------KVKASPMTPEQAMKQYIQKLTAFEHHEIFSYPEIYFLGPNAKKRQGMTGGPNNGGYDDDQGSYVQVPHDHVAYRYEVLKVIGKGSFGQVVKAYDHKVHQHVALKMVRNEKRFHRQAAEEIRILEHLRKQDKDNTMNVIHMLENFTFRNHICMTFELLSMNLYELIKKNKFQGFSLPLVRKFAHSILQCLDALHKNRIIHCDLKPENILLKQQGRSSIKVIDFGSSCYEHQRVYTYIQSRFYRAPEVILGARYGMPIDMWSLGCILAELLTGYPLLPGEDEGDQLACMIELLGMPSQKLLDASKRAKNFVSSKGYPRYCTVTTLSDGSVVLNGGRSRRGKLRGPPESREWGNALKGCDDPLFLDFLKQCLEWDPAVRMTPGQALRHPWLRRRLPKPPTG----------------------EKTAVKRVTESTGAITSISKLPPPSSSASKLRTNLAQMTDAN--------------------------GNIQQRTVLP----------------------------------KLVS-------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5U4C9-1", "uniprot_id": "DYRK2_MOUSE", "id": "Q5U4C9-1", "name": "Dual specificity tyrosine-phosphorylation-regulated kinase 2", "aln": "-----------MLTRKPSAAAPAAYPTGRGGDTAVRQLQASPG---------IGAGAPRSGVGTGPPSPIALPPLRAS------NATTTAHTIGGSKHTMNDHLHLN---SHGQIQVQQLFEDNSNKRTVLTTQPNGLTTVGKTG------LPGVPERQLESIHRRQGSSTSLKSMEGMG----------------------KVKASPMTPEQAMKQYMQKLTAFEHHEIFSYPEIYFLGPNAKKRQGMTGGPNNGGYDDDQGSYVQVPHDHVAYRYEVLKVIGKGSFGQVVKAYDHKVHQHVALKMVRNEKRFHRQAAEEIRILEHLRKQDKDNTMNVIHMLENFTFRNHICMTFELLSMNLYELIKKNKFQGFSLPLVRKFAHSILQCLDALHKNRIIHCDLKPENILLKQQGRSSIKVIDFGSSCYEHQRVYTYIQSRFYRAPEVILGARYGMPIDMWSLGCILAELLTGYPLLPGEDEGDQLACMIELLGMPSQKLLDASKRAKNFVSSKGYPRYCTVTTLSDGSVVLNGGRSRRGKLRGPPESREWGNALKGCDDPLFLDFLKQCLEWDPAVRMTPGQALRHPWLRRRLPKPPTG----------------------EKTAVKRVTESTGAITSISKLPPPSSSASKLRTNLAQMTDAN--------------------------GNIQQRTVLP----------------------------------KLVS-------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92630-1", "uniprot_id": "DYRK2_HUMAN", "id": "Q92630-1", "name": "Dual specificity tyrosine-phosphorylation-regulated kinase 2", "aln": "-----------MLTRKPSAAAPAAYPTGRGGDSAVRQLQASPG---------LGAGATRSGVGTGPPSPIALPPLRAS------NAAAAAHTIGGSKHTMNDHLHVGSH-AHGQIQVQQLFEDNSNKRTVLTTQPNGLTTVGKTG------LPVVPERQLDSIHRRQGSSTSLKSMEGMG----------------------KVKATPMTPEQAMKQYMQKLTAFEHHEIFSYPEIYFLGLNAKKRQGMTGGPNNGGYDDDQGSYVQVPHDHVAYRYEVLKVIGKGSFGQVVKAYDHKVHQHVALKMVRNEKRFHRQAAEEIRILEHLRKQDKDNTMNVIHMLENFTFRNHICMTFELLSMNLYELIKKNKFQGFSLPLVRKFAHSILQCLDALHKNRIIHCDLKPENILLKQQGRSGIKVIDFGSSCYEHQRVYTYIQSRFYRAPEVILGARYGMPIDMWSLGCILAELLTGYPLLPGEDEGDQLACMIELLGMPSQKLLDASKRAKNFVSSKGYPRYCTVTTLSDGSVVLNGGRSRRGKLRGPPESREWGNALKGCDDPLFLDFLKQCLEWDPAVRMTPGQALRHPWLRRRLPKPPTG----------------------EKTSVKRITESTGAITSISKLPPPSSSASKLRTNLAQMTDAN--------------------------GNIQQRTVLP----------------------------------KLVS-------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P83102-1", "uniprot_id": "DYRK3_DROME", "id": "P83102-1", "name": "Putative dual specificity tyrosine-phosphorylation-regulated kinase 3 homolog", "aln": "MVGSQEKKNNHIELSETPATDKNNLNTTHLENTQLSKALSPPTSLPQIQIQMINQNLTHTGIAQNNTEKANRHQYRDSGLQYLTRCFEPLAMLNDSKEDFPTQPSNNIANYPGDIQILPIFDCCEISESIQAISLPNVTSPSKTKDVPGLFLRTISENSKSKSEPECESLISVKESSVMENHTFLFHEQIIMSGQQKCELHEKPKVLVVSPQQVMILYMNKLTPYERTEILTYPQIYFIGANAKKRPGVYG-PNNSEYDNEQGAYIHVPHDHVAYRYEMLKIIGKGSFGQVIKAYDHKTHEHVALKIVRNEKRFHRQAQEEIRILHHLRRHDKYNTMNIIHMFDYFTFRNHTCITFELLSINLYELIKKNGFKGFSLQLVRKFAHSLLQCLDALYKNDIIHCDMKPENVLLKQQGRSGIKVIDFGSSCFENQRIYTYIQSRFYRAPEVILGGKYGRAIDMWSLGCILAELLSGHALFPGENESDQLACIIEVLGMPNKNILASSKRSKSFFSPKGYPRYCTVRTMSDGMVVLIGGQSRRGKQRGPPCSKSLSKALDGCKDPLFLNFIRGCLEWDADKRLTPSEALKHPWLRRRLPRPPSSSSGCGGVSGLCSSRNESPVTGQNRNFAAETTASSTSATSISLTIKRENSHSSLRLHHGAVPETDFKLIKSVPEGSSTATKEPMMNSDILPESFRQTTVVSPSKHSADSGGMSCLSAVDVGPSRYYPYMNNNENNRLFSSSLNSSANSLSHLEQATKLDALGEYSASTTPNLLSKNTGYSFNSGSINIDVAQESLVNIASNYALDKSIDIIGKSNVSLHTNKLKVQSKDM", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :..*: * : :: : : :.* :. . .::*:. . .. * * .. . :...*. : : . *:**: :*: . ..:: : . .:*: .** * :.*.. .. . . * *:*. . * * *. ::*:*.* *::***.:*: **::**:***:* ***** *: * ***. **::**:*::***********:**:*********:******.*:*****:*********** ******.***::** ****:***:: ****** *:******:********* *:**** ********:*******:** *****:****:********.**********:*:**:*****************.:** .**************:*:.*:***:*.*****:**:****.:::* :***:*.*.*.********* *:*** *** **:***** **** *:. .:**.**.*****:*:: *****. *:**.:**:*********:**:. ::. . . * *: : **** ..* *.** : . :.::: .::* **:. :*.* ", "identical_positions": 321, "similar_positions": 167, "identity": "38.72%" }, { "cls_id": "homologset.agr.MGI:1330302", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZP97-1", "uniprot_id": "A0A8I5ZP97_RAT", "id": "A0A8I5ZP97-1", "name": "dual-specificity kinase", "aln": "---------------MLAARPPHWGPHRAPAPRGPSASPDPGLSGGGSRGAGCEKAPPGRAPAPGLTPLRPSEPTMAVPPGHGPFSGFPGPQEHTQVLPDVRLLPRRLPLAFRDATSAPLRKLSVDLIKTYKHINEVYYAKKKRRAQQAP-PQDSSTKKEKKVLNHGYDDDNHDYIVRSGERWLERYEIDSLIGKGSFGQVVKAYDHQTQELVAIKIIKNKKAFLNQAQIELRLLELMNQHDTEMKYYIVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTHFRGVSLNLTRKLAQQLCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGTPYDLAIDMWSLGCILVEMHTGEPLFSGSNEVRPWKGCTGGGGVEPGHLAPLTAACLQVDQMSRIVEVLGIPPAPMLEQAPKARKYFERLP-GGGWTLRRTKELRK-------DYQGPGTRRLQEVLGVQTGGPGGRRAGEPGHSPADYLRFQDLVLRMLEYEPAARISPLGALQHGFFRRTADEATNTGPAGSSASTSPAPLDTCPSSSTAS---------SISSSGGSSGSSSDNRAYRYSNRYCGGPGPPITDCEMNSPQVLPSQPLRP------------WAGGD----------------------------VPHKTHQAPTSGSTLLGTG--------------------------------------------------------------AQLPPQPR----CLGRPPSPTSP------------------------------------PPPELMDVSLVGS--------------------PPDCS----PPHPAPAPQHPAASALR-----------------------TRMTGGRPP----------------------LPPPDDPATLGPRLGLHGVPQSTAASS----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z188-1", "uniprot_id": "DYR1B_MOUSE", "id": "Q9Z188-1", "name": "Dual specificity tyrosine-phosphorylation-regulated kinase 1B", "aln": "---------------------------------------------------------------------------MAVPPGHGPFSGFPGPQEHTQVLPDVRLLPRRLPLAFRDAASAPLRKLSVDLIKTYKHINEVYYAKKKRRAQQAP-PQDSSTKKEKKVLNHGYDDDNHDYIVRSGERWLERYEIDSLIGKGSFGQVVKAYDHQTQELVAIKIIKNKKAFLNQAQIELRLLELMNQHDTEMKYYIVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTHFRGVSLNLTRKLAQQLCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGTPYDLAIDMWSLGCILVEMHTGEPLFSGSN---------------------------EVDQMSRIVEVLGIPPAPMLEQAPKARKYFERLP-GGGWTLRRTKELRK-------DYQGPGTRRLQEVLGVQTGGPGGRRAGEPGHSPADYLRFQDLVLRMLEYEPAARISPLGALQHGFFRRTADEATNTGPAGSSASTSPAPLDTCPSSSTAS---------SISSSGGSSGSSNDNRAYRYSNRYCGGPGPPITDCEMNSPQVLPSQPLRP------------WAGGD----------------------------VPHKTHQAPISASTLPGTG--------------------------------------------------------------AQLPPLPR----CLGRPPSPTSP------------------------------------PPPELMDVSLVGS--------------------PPDCS----PPPPAPAPQHPAASALR-----------------------TRMTGGRPP----------------------LPPPDDPATLGPRLGLHGVPQSTAASS----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y463-1", "uniprot_id": "DYR1B_HUMAN", "id": "Q9Y463-1", "name": "Dual specificity tyrosine-phosphorylation-regulated kinase 1B", "aln": "---------------------------------------------------------------------------MAVPPGHGPFSGFPGPQEHTQVLPDVRLLPRRLPLAFRDATSAPLRKLSVDLIKTYKHINEVYYAKKKRRAQQAP-PQDSSNKKEKKVLNHGYDDDNHDYIVRSGERWLERYEIDSLIGKGSFGQVVKAYDHQTQELVAIKIIKNKKAFLNQAQIELRLLELMNQHDTEMKYYIVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTHFRGVSLNLTRKLAQQLCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGTPYDLAIDMWSLGCILVEMHTGEPLFSGSN---------------------------EVDQMNRIVEVLGIPPAAMLDQAPKARKYFERLP-GGGWTLRRTKELRK-------DYQGPGTRRLQEVLGVQTGGPGGRRAGEPGHSPADYLRFQDLVLRMLEYEPAARISPLGALQHGFFRRTADEATNTGPAGSSASTSPAPLDTCPSSSTAS---------SISSSGGSSGSSSDNRTYRYSNRYCGGPGPPITDCEMNSPQVPPSQPLRP------------WAGGD----------------------------VPHKTHQAPASASSLPGTG--------------------------------------------------------------AQLPPQPR----YLGRPPSPTSP------------------------------------PPPELMDVSLVGG--------------------PADCS----PPHPAPAPQHPAASALR-----------------------TRMTGGRPP----------------------LPPPDDPATLGPHLGLRGVPQSTAASS----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B533-1", "uniprot_id": "A0A8M2B533_DANRE", "id": "A0A8M2B533-1", "name": "dual-specificity kinase", "aln": "MVITSSVEEKPQPSNRMVANLPTESWIGSPDQNRFLPQSHLLRKPARSGSSSGCKPPSSTLCQPAALGFSPAEPTMSSQHSHPSFSNIHSMADQQQVLSDMTILQRRIPPSFRDPASAPLRKLSVDLIKTYKHINEVYYTKKKRRAQQVP-PEDSSTKKERKVYNDGYDDDNYDYIVKNGEKWLDRYEIDSLIGKGSFGQVVKAYDHHEQEWVAIKIIKNKKAFLNQAQIELRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTNFRGVSLNLTRKFAQQLCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGSN---------------------------EVDQMNKIVEVLGVPPNHMLDQAPKARKYFDKLS-DGLWTVKKNKDIKKVLYPSASEYKPPATRRLHEILGVETGGPGGRRAGEQGHAPCDYLKFKDLILRMLDYDPKTRITPFYALQHNFFKKTTDEGTNT---SSSTSTSPA-MDHSHSTSTTS---------SVSSSGGSSGSSNDNRNYRYSNRYYN-SAVTHTDYEMQSPQAPSQQQLRI------------WPGGDS----------SMGQLSNSGSDSSYPQLLLHKPAATQHSRHFLGNIGGM-------------------------------------------MEPHHPHPIYGSHHSNGRQLRQQQQ----QQNQPQGQASQGQQGTALMPVSSPQMQDSIELSLTHHHHLGQSSIMQPPPSSLDSSQYGSSNLHLGLSAFRTRTVMAPQQPPSASQQQLPQAPASQDSMVAASGLGYIPPCYAGSNNNNNPPQGSVGVGAMLTGGPPPRGVGGAGG--------------RPDSEESSMMAVCGSGSGSGQSAANS-----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P49657-1", "uniprot_id": "MNB_DROME", "id": "P49657-1", "name": "Serine/threonine-protein kinase minibrain", "aln": "-----------------MYRLEDTNSGGVMDKNKQKLSAYGSSGGSVDAAQGSGSGGGRQRHAPLYGRFVDAED---LPATHRDVMHHHSSPSSS---SEVRAMQARIPNHFREPASGPLRKLSVDLIKTYKHINEVYYAKKKRRAQQTQGDDDSSNKKERKLYNDGYDDDNHDYIIKNGEKFLDRYEIDSLIGKGSFGQVVKAYDHEEQCHVAIKIIKNKKPFLNQAQIEVKLLEMMNRADAENKYYIVKLKRHFMWRNHLCLVFELLSYNLYDLLRNTNFRGVSLNLTRKFAQQLCTALLFLSTPELNIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYHYIQSRFYRSPEVLLGIQYDLAIDMWSLGCILVEMHTGEPLFSGCN---------------------------EVDQMNKIVEVLGMPPKYLLDQAHKTRKFFDKIVADGSYVLKKNQNGRK--------YKPPGSRKLHDILGVETGGPGGRRLDEPGHSVSDYLKFKDLILRMLDFDPKTRVTPYYALQHNFFKRTADEATNTSGAGATANAGAGGSGSSGAGGSSGGGVGGGLGASNSSSGAVSSSSAAAPTAATAAATAAGSSGSGSSVGGGSSAAQQQQAMPLPLPLPLPLPPLAGPGGASDGQCHGLLMHSVAANAMNNFSALSLQSNAHPPPSLANSHHSTNSLGSLNHISPGSTGCHNNNSNSSNNNTRHSRLYGSNMVNMVGHHNSGSSNNHNSISYPHAMECDPPQMPPPPPNGHGRMRVPAIMQLQPNSYAPNSVPYYGNMSSSSVAAAAAAAAAAASHLMMTDSSVISASAAGGGQ--------GGGNPGQNPVTPSAAAFLFPSQPAGTLYGTALGSLSDLP--LPMPLPMSVPLQLPPSSSSSVSSGSASVGSGGVGVGVVGQRRHITGPAAQVGISQSVGSGSSGSATGASSSDASSSSPMVGVCVQQNPVVIH", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . . . .:: : *:* **:.:*.*********************:********. :***.***:*: *.******:***::.**::*:**********************. * **********.********::***:**: *:* *****:******:**********************:***********:***********:****.*************************************:*************** **************************.* :****.:******:** :*:** *:**:*::: .* :.:::.:: :* *: *.:*:*:::***:******** .* **: .***:*:**:****:::* :*::* ****.**::*:**.*** .:::.:... . . : .::. * ****. *.** : .. . :. *. . .* : .** * . * . * *: * . .. :. * *. ....: * ** * ..* : ::.* .. .:. . . * .* * * ", "identical_positions": 334, "similar_positions": 144, "identity": "34.22%" }, { "cls_id": "homologset.agr.MGI:1330304", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O55166-1", "uniprot_id": "VPS52_RAT", "id": "O55166-1", "name": "Vacuolar protein sorting-associated protein 52 homolog", "aln": "MAAAATMAAAARELVLRAGASDMEEEEGPLGAGSGLQEPLQLGELDITSDEFILDEVDVHIQANLEDELVKEALKTGVDLRHYSKQVELELQQIEQKSIRDYIQESENIASLHNQITACDAVLERMEQMLGAFQSDLSSISCEIRTLQEQSGAMNIRLRNRQAVRGKLGELVDGLVVPSALVTAILEAPVTEPRFL--------------EQLQELDAKAAAVREQEARGTAACADVRGVLDRLRVKAVTKIREFILQKIYSFRKP-MTNYQIPQTALLKYRFFYQFLLGNERATAKEVRDEYVETLSKIYLSYYRSYVGRLMKVQYEEVAEKDDLMGVEDTAKKGFFSKP-SLRSRNTIFTLGT--------------------RGAVISPAELEAPILVPHTAQRGEQRYPFEALFRSQHYALLDNSCREYLFICEFFVVSG---PAAHDLFHAVMGRTLSMTLKHLESYLADCYDAIAVFLCIHIVLRFRNIAAKRDVP-ALDRYWEQVLALLWPRFELILEMNVQSVRSTDPQRLGGLDTRPHYITRRYAEFSSALVSINQTIPNERTLQLLGQLQVEVENFVLRVAAEFSSRKEQLVFLINNYDMMLGVLMERAADDSKEVESFQQLLNARTQEFIEELLSPPFGGLVAFVKEAEALIERGQAERLRGEEARVTQLIRGFGSSWKASVESLSQDVMRSFTNFRNGTSIIQGALTQLIQLYHRFHRVLSQPQLRALPARAELINIHHLMVELKKHKPNF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C754-1", "uniprot_id": "VPS52_MOUSE", "id": "Q8C754-1", "name": "Vacuolar protein sorting-associated protein 52 homolog", "aln": "MAAAATMAAAARELVLRAGASDVEEEEGPLGGGSGLQEPLQLGELDITSDEFILDEVDVHIQANLEDELVKEALKTGVDLRHYSKQVELELQQIEQKSIRDYIQESENIASLHNQITACDAVLERMEQMLGAFQSDLSSISSEIRTLQEQSGAMNIRLRNRQAVRGKLGELVDGLVVPSALVTAILEAPVTEPRFL--------------EQLQELDAKAAAVREQEAMGTAACADVRGVLDRLRVKAVTKIREFILQKIYSFRKP-MTNYQIPQAALLKYRFFYQFLLGNERATAKEIRDEYVETLSKIYLSYYRSYVGRLMKVQYEEVAEKDDLMGVEDTAKKGFFSKP-SLRSRNTIFTLGT--------------------RGTVISPAELEAPILVPHTAQRGEQRYPFEALFRSQHYALLDNSCREYLFICEFFIVSG---PAAHDLFHAVMGRTLSMTLKHLESYLADCYDAIAVFLCIHIVLRFRNIAAKRDVP-ALDRYWEQVLALLWPRFELILEMNVQSVRSTDPQRLGGLDTRPHYITRRYAEFSSALVSINQTIPNERTLQLLGQLQVEVENFVLRVAAEFSSRKEQLVFLINNYDMMLGVLMERAADDSKEVESFQQLLNARTQEFIEELLSPPFGGLVAFVKEAEALIERGQAERLRGEEARVTQLIRGFGSSWKASVESLSQDVMRSFTNFRNGTSIIQGALTQLIQLYHRFHRVLSQPQLRALPARAELINIHHLMVELKKHKPNF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N1B4-1", "uniprot_id": "VPS52_HUMAN", "id": "Q8N1B4-1", "name": "Vacuolar protein sorting-associated protein 52 homolog", "aln": "MAAAATMAAAARELVLRAGTSDMEEEEGPLAGGPGLQEPLQLGELDITSDEFILDEVDVHIQANLEDELVKEALKTGVDLRHYSKQVELELQQIEQKSIRDYIQESENIASLHNQITACDAVLERMEQMLGAFQSDLSSISSEIRTLQEQSGAMNIRLRNRQAVRGKLGELVDGLVVPSALVTAILEAPVTEPRFL--------------EQLQELDAKAAAVREQEARGTAACADVRGVLDRLRVKAVTKIREFILQKIYSFRKP-MTNYQIPQTALLKYRFFYQFLLGNERATAKEIRDEYVETLSKIYLSYYRSYLGRLMKVQYEEVAEKDDLMGVEDTAKKGFFSKP-SLRSRNTIFTLGT--------------------RGSVISPTELEAPILVPHTAQRGEQRYPFEALFRSQHYALLDNSCREYLFICEFFVVSG---PAAHDLFHAVMGRTLSMTLKHLDSYLADCYDAIAVFLCIHIVLRFRNIAAKRDVP-ALDRYWEQVLALLWPRFELILEMNVQSVRSTDPQRLGGLDTRPHYITRRYAEFSSALVSINQTIPNERTMQLLGQLQVEVENFVLRVAAEFSSRKEQLVFLINNYDMMLGVLMERAADDSKEVESFQQLLNARTQEFIEELLSPPFGGLVAFVKEAEALIERGQAERLRGEEARVTQLIRGFGSSWKSSVESLSQDVMRSFTNFRNGTSIIQGALTQLIQLYHRFHRVLSQPQLRALPARAELINIHHLMVELKKHKPNF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VMQ8-1", "uniprot_id": "Q9VMQ8_DROME", "id": "Q9VMQ8-1", "name": "Vacuolar protein sorting-associated protein 52 homolog", "aln": "----------------------MAEVPSPQ------------------------------MTEQLDNEEVREILKNTTDLRQYSRQIEKEFKEVENKSIEDYIAESQNIANLHNQINDCDDVLERMENMLMSFQSVLNNISTEITQLQRKSVSMSLQLTNRQSVKAQLSQFIEDMAVSEEMINIIMETPVTERDFS--------------TQLNVLNHKLSLVKELSFKESKSTSDVSDVLQKLRLKAMAKIRSYLLEQIYKFRKP-MTNYQIPQNAMLKHKFFFEFILSNERHVAQEICSEYIDTMGKIYYSYFKSYSTRLTSLKFEESCTKDDLMGIEDNASKGLFSKTTSLKHKSTIFTIGK--------------------RGDILN-QQLEAPIIVPHAQLKN--RYTAEALFRSEQYALVDNACREYLFVTEFFMVRG---TQAQDLFNQIMGKTLTLMIKNLETSIHDCFDTIAMFLCIHLIFRYQLMCHKRCVP-ALDKYWDSLQAVIWPRFELVFRLNIQSIHDCDPTKFN-KELGPHYITRRYAEFSAAIVGISEHFPNELVSRLLLELQNEVECFILRMAAIFPTRKDQLIYLINNYDLVLGVLMEHTRDNSKEAEAFREQLNSRSAEYVEEILAPHFGGIIQFVKECEHFFEKEQMDELRKQERRSLALVASFSANWKKSLEELNREVLLSFPSLLTGSQLLQLALASLVQYYHRFHKLLTPN------ARAQLTNIHVVMVEIKKYKSNY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39904-1", "uniprot_id": "VPS52_YEAST", "id": "P39904-1", "name": "Vacuolar protein sorting-associated protein 52", "aln": "----------------------MDVLKEVLS-------------------------LDQDKFDQLKETSRDKTNETDDPFENYLK--DCKFKAPSNKDQSPFAKLKSLQETHSNNEAAINIIIPQLIDYLTEFTNRLSNYTQDLDFIKKKSNELQSLLEYNSTKLAHISPMVNDLMIPPELIDDIIKGKINESWQDNITFIADKEEIYNKYRSNNLDQDNKDAENSAMLAPKDFDKLCQLLDILKNVILERSKRLIISKIKTLRSHNPVPSQRIQNKLLKVQKIFPFIRDNNLSLALELRQAYCYTMKWYYREYFSRYIRSLTILQFQQIDSQFALGNGLSTTSVSGFNNSPSLFFSNYLTTSASNAFYNKLPVTDEKIDKYFQIKKRLNILTQEDNTVMVSQIAENNTTKNYIEIGFKNLNLAILDNCTVEYHFLKDFFAMNGDNFEEINGLLEQIFQPTFDEATTYTQQLIQYNYDIFGVLISIRVANQLQFESERRGIPSMFDSFLNGQLIQLWPRFQQLVDFQCESLR----------KAAITTNVAKYAGNSSTSNSSPLTSPHELTVQFG-KFLSSFLTLAITHKQSIDERSEPLYNSIIRLRNDFETVMTKCSKKTKSPE---------------RFLATNYMYLYNNLQQLHLHLNINDSDAQNYN---------------FDSAENVGTKVANDDDNDSSVPLIIRETENHFKTLVEAFTRN--------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :*.: : :. :.:* : : ::: .:*. : .. . *: : :: :: : * * . *.. : :: ::.:* :. * ..: .::. :::.: :. :: *:: :.* : : *: . ..: . .: :*: *: : : : ::.:* .:*. . * * :** : :: *: .*: * *: . * *: * .*: * * ::::: : * . ..:. . *.:. ** . : * .. : : : : .::*.: .. : * *:. : *::**. ** *: :** : * :.*:. :: *: . : : :* :.:::.*:: : : . :* :* :* : : :****: :. :: :*:: . . :** *:: . *:* . :: :: .. : : : *.: * * . : .:* : ..:*. * .:*:. : : ::: . :: : : . : * *.:. .* . . . . ::: : : . * : ", "identical_positions": 75, "similar_positions": 232, "identity": "9.83%" }, { "cls_id": "homologset.agr.MGI:1330305", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q2WEA5-1", "uniprot_id": "TRPM1_RAT", "id": "Q2WEA5-1", "name": "Transient receptor potential cation channel subfamily M member 1", "aln": "----------------------------------MGSMRKMSSSFKRGS----------------------------IKSSTSGS-------------------------QKGQKAWIEKTFCKRECIFVIPSTKDPNRCCCG--QLTNQHIPPLPSVTPSSTAE-DTKQGDAQSGKWSVSKHTQSYPTDSYGILEFQGGGYSNKAMYIRVSYDTKPDSLLHLMVKDWQLELPKLLISVHGGLQSFEMQPKLKQVFGKGLIKAAMTTGAWIFTGGVSTGKSVVSHVGDALKDHSSKSRGRLCAIGIAPWGMVENKEDLVGKDVTRVYQTMSNPLSKLSVLNNSHTHFILADNGTLGKYGAEVKLRRQLEKHISLQKINTRLGQGVPVVGLVVEGGPNVVSIVLEYLREDPPVPVVVCDGSGRASDILSFAHKYCDEG--GVINESLRDQLLVTIQKTFNYSKSQSHQLFAIIMECMKKKELVTVFRMGSEGQ---QDVEMAILTALLKGTNVSAPDQLSLALAWNRVDIARSQIFVFGPHWPPLGSLAPPVDTKVAEKEKKPPTATTKG-RGKGKGKKKGKVKEEVEEETDPRKIELLNWVNALEQAMLDALVLDRVDFVKLLIENGVNMQHFLTIPRLEELYNTRLGPPNTLHLLVRDVKKSNLPPDYHISLIDIGLVLEYLMGGAYRCNYTRKSFRTLYNNLFGPKRPKALKLLGMEDDEPPAKGKKKKKKKKEEEIDIDVDDPAVSRFQYPFHELMVWAVLMKRQKMAVFLWQRGEECMAKALVACKLYKAMAHESSESELVDDISQDLDNNSKDFGQLAVELLDQSYKHDEQVAMKLLTYELKNWSNSTCLKLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNPGLKVIMGILIPPTILFLEFRSYDDFSYQTSKENEDGK----EKEE-----ENVDANADAGSRKGD--------------------------EENEHKKQRSIPIGTKICEFYNAPIVKFWFYTISYLGYLLLFNYVILVRMDGWPSPQEWIVISYIVSLALEKIREILMSEPGKLSQKIKVWLQEYWNITDLVAISMFMVGAILRLQNQPYMGYGRVIYCVDIILWYIRVLDIFGVNKYLGPYVMMIGKMMIDMLYFVVIMLVVLMSFGVARQAILHPEEKPSWKLARNIFYMPYWMIYGEVFADQIDRKTRIHIYAMEINPPCGENLYDEEGKRLPPCIPGAWLTPALMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHDRPVLPPPMIILSHIYIIVMRLSGRCRKKREGDQEERDRGLKLFLSDEELKKLHEFEEQCVQEHFREKEDEQQSSSDERIRVTSERVENMSMRLEEINERENFMKASLQTVDLRLSQLEELSGRMVGALENLAGIDRSDLIQARSRASSECEAT---YLLRQSSINSADGYS-------------------------------MYRYHFN-------------GEELLFEEPALSTSPGTVFRKKTCS-------FRVKEE-DVKSHLD--QPSSLHHTPGPSPPATP-----------------------------------------------------------------------GRSRLALDGPLST-ELRPGLDPGISAGELDPRADFKS------------------------AEVAPSLN---------TANVASTQLTVEST-------------------------------------------------------VSHPLRESKLARYYPGD----------------------------LNTYKTMKSRSFVYSEGRKLVRGLSNWGAEYSS----------IMDQTWNSAEWRCQVQRITRSRSTDIPY-------IVSEAASQDE--------------------FEDEHRESLLAPQISRSALTVSDRPEKENLLSVKPHQTLGFPCLRSRSLHGH---PRSAKPSPS-------------------------------KLDRAGHASSTSNLAVMS-DAPEGQNTQQEKGNPETEC--------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q2TV84-1", "uniprot_id": "TRPM1_MOUSE", "id": "Q2TV84-1", "name": "Transient receptor potential cation channel subfamily M member 1", "aln": "----------------------------------MGSMRKMSSSFKRGS----------------------------IKSSTSGS-------------------------QKGQKAWIEKTFCKRECIFVIPSTKDPNRCCCG--QLTNQHIPPLPSGAPSTTGE-DTKQADTQSGKWSVSKHTQSYPTDSYGILEFQGGGYSNKAMYIRVSYDTKPDSLLHLMVKDWQLELPKLLISVHGGLQSFEMQPKLKQVFGKGLIKAAMTTGAWIFTGGVSTG--VVSHVGDALKDHSSKSRGRLCAIGIAPWGMVENKEDLIGKDVTRVYQTMSNPLSKLSVLNNSHTHFILADNGTLGKYGAEVKLRRQLEKHISLQKINTRLGQGVPVVGLVVEGGPNVVSIVLEYLKEDPPVPVVVCDGSGRASDILSFAHKYCDEG--GVINESLRDQLLVTIQKTFNYSKSQSYQLFAIIMECMKKKELVTVFRMGSEGQ---QDVEMAILTALLKGTNASAPDQLSLALAWNRVDIARSQIFVFGPHWPPLGSLAPPVDTKATEKEKKPPTATTKG-RGKGKGKKKGKVKEEVEEETDPRKLELLNWVNALEQAMLDALVLDRVDFVKLLIENGVNMQHFLTIPRLEELYNTRLGPPNTLHLLVRDVKKSNLPPDYHISLIDIGLVLEYLMGGAYRCNYTRKSFRTLYNNLFGPKRPKALKLLGMEDDEPPAKGKKKKKKKKEEEIDIDVDDPAVSRFQYPFHELMVWAVLMKRQKMAVFLWQRGEECMAKALVACKLYKAMAHESSESELVDDISQDLDNNSKDFGQLAVELLDQSYKHDEQVAMKLLTYELKNWSNSTCLKLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNPGLKVIMGILIPPTILFLEFRTYDDFSYQTSKENEDGK----EKEE-----ENVDANADAGSRKGD--------------------------EENEHKKQRSIPIGTKICEFYNAPIVKFWFYTISYLGYLLLFNYVILVRMDGWPSPQEWIVISYIVSLALEKIREILMSEPGKLSQKIKVWLQEYWNITDLVAISMFMVGAILRLQSQPYMGYGRVIYCVDIILWYIRVLDIFGVNKYLGPYVMMIGKMMIDMLYFVVIMLVVLMSFGVARQAILHPEEKPSWKLARNIFYMPYWMIYGEVFADQID------LYAMEINPPCGENLYDEEGKRLPPCIPGAWLTPALMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHDRPVLPPPMIILSHIYIIIMRLSGRCRKKREGDQEERDRGLKLFLSDEELKKLHEFEEQCVQEHFREKEDEQQSSSDERIRVTSERVENMSMRLEEINERENFMKTSLQTVDLRLSQLEELSGRMVSALENLAGIDRSDLIQARSRASSECEAT---YLLRQSSINSADGYS-------------------------------LYRYHFN-------------GEELLFEEPALSTSPGTAFRKKTYS-------FRVKDE-DAKSHLD--QPSNLHHTPGPSPPATP-----------------------------------------------------------------------GRSRLALEGPLST-ELRPGSDPGISAGEFDPRADFKS------------------------TEAAPSLN---------AAGVTGTQLTVEST-------------------------------------------------------DSHPLRESKLVRYYPGD----------------------------PNTYKTMKSRSFVYTEGRKLVRGLSNWSAEYSS----------IMDQAWNATEWRCQVQRITRSRSTDIPY-------IVSEAASQDE--------------------LEDEHRGSLLDPQISRSALTVSDRPEKENLLSVKPHQTLGFPCLRSRSLHGR---PRSAEPAPS-------------------------------KLDRAGHASSTSNLAVMS-VVPEGQNTQQEKRSAETEC--------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7Z4N2-1", "uniprot_id": "TRPM1_HUMAN", "id": "Q7Z4N2-1", "name": "Transient receptor potential cation channel subfamily M member 1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------MKDSNRCCCG--QFTNQHIPPLPSATPSKNEE-ESKQVETQPEKWSVAKHTQSYPTDSYGVLEFQGGGYSNKAMYIRVSYDTKPDSLLHLMVKDWQLELPKLLISVHGGLQNFEMQPKLKQVFGKGLIKAAMTTGAWIFTGGVSTG--VISHVGDALKDHSSKSRGRVCAIGIAPWGIVENKEDLVGKDVTRVYQTMSNPLSKLSVLNNSHTHFILADNGTLGKYGAEVKLRRLLEKHISLQKINTRLGQGVPLVGLVVEGGPNVVSIVLEYLQEEPPIPVVICDGSGRASDILSFAHKYCEEG--GIINESLREQLLVTIQKTFNYNKAQSHQLFAIIMECMKKKELVTVFRMGSEGQ---QDIEMAILTALLKGTNVSAPDQLSLALAWNRVDIARSQIFVFGPHWPPLGSLAPPTDSKATEKEKKPPMATTKGGRGKGKGKKKGKVKEEVEEETDPRKIELLNWVNALEQAMLDALVLDRVDFVKLLIENGVNMQHFLTIPRLEELYNTRLGPPNTLHLLVRDVKKSNLPPDYHISLIDIGLVLEYLMGGAYRCNYTRKNFRTLYNNLFGPKRPKALKLLGMEDDEPPAKGKKKKKKKKEEEIDIDVDDPAVSRFQYPFHELMVWAVLMKRQKMAVFLWQRGEESMAKALVACKLYKAMAHESSESDLVDDISQDLDNNSKDFGQLALELLDQSYKHDEQIAMKLLTYELKNWSNSTCLKLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNPGLKVIMGILLPPTILFLEFRTYDDFSYQTSKENEDGK----EKEE-----ENTDANADAGSRKGD--------------------------EENEHKKQRSIPIGTKICEFYNAPIVKFWFYTISYLGYLLLFNYVILVRMDGWPSLQEWIVISYIVSLALEKIREILMSEPGKLSQKIKVWLQEYWNITDLVAISTFMIGAILRLQNQPYMGYGRVIYCVDIIFWYIRVLDIFGVNKYLGPYVMMIGKMMIDMLYFVVIMLVVLMSFGVARQAILHPEEKPSWKLARNIFYMPYWMIYGEVFADQID------LYAMEINPPCGENLYDEEGKRLPPCIPGAWLTPALMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHDRPVLPPPMIILSHIYIIIMRLSGRCRKKREGDQEERDRGLKLFLSDEELKRLHEFEEQCVQEHFREKEDEQQSSSDERIRVTSERVENMSMRLEEINERETFMKTSLQTVDLRLAQLEELSNRMVNALENLAGIDRSDLIQARSRASSECEAT---YLLRQSSINSADGYS-------------------------------LYRYHFN-------------GEELLFEDTSLSTSPGTGVRKKTCS-------FRIKEEKDVKTHLVPECQNSLHLSLGTSTSATP-----------------------------------------------------------------------DGSHLAVDDLKNAEESKLGPDIGISKEDDERQTDSKKE-----------------------ETISPSLNKTDVIHGQDKSDVQNTQLTVETTNIEGT--------------------------------------------------ISYPLEETKITRYFPDET---------------------------INACKTMKSRSFVYSRGRKLVGGVN-QDVEYSS----------ITDQQL-TTEWQCQVQKITRSHSTDIPY-------IVSEAAVQAEHKEQFA-------------DMQDEHHVAEAIPRIPRLSLTITDRNGMENLLSVKPDQTLGFPSLRSKSLHGH---PRNVKSIQG-------------------------------KLDRSGHASSVSSLVIVSGMTAEEKKVKKEKASTETEC--------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6Z1K6-1", "uniprot_id": "A0A8M6Z1K6_DANRE", "id": "A0A8M6Z1K6-1", "name": "", "aln": "-----------------------------MDNRGFGAKKAKEGSFKRAS----------------------------IKRTSSGS-------------------------QKAQRAWIERTFLKRECNHIFP-SKEPNRCCCG--QLVNQHVAILPGSTNKNVEEGQVVPIEPPQEKWSVAKHTQAMPTDSYGIIEFQGGGHINKAMYIRVSYDTKPDNLLHLMVKDWQLELPTLLISVHGGLQNFDLQPKLKQVFGKGLIKAAVTTGAWIFTGGVSTG--VIRHVGDALKDHSSKSRGKVCAIGIAPWGIVENKEDLIGRDVTRPYQTMSNPLSKLSVLNNSHSHFILADNGTHGKYGAEVRLRRQLEKHISLQKINTRLGQGVPLVCLILEGGPNVISIVLESLREDPPVPVVVCDGSGRASDIISFAHKYSEQD--GLVNDSVRDQLLVTIQKTFNYNRNQAQQIYLMVMECMKKRELITVFRTASEGQ---QDIEMAILTALLKGTNASAPDQLSLALAWNRVDIARSQIFVHGQHWPPAGSLPTSSTGQQDKPKSPIATRVSKGKPARGKKGKGAKSKPEPPEETDPRKLELLNWVNSLEQAMMDALVLDRVDFVKLLIENGVNIHHFLTIPRLEELYNTRLGPINTLHFVVRDVKKGNLPPDYQITLIDIGLVLEYLMGGAYRCNYTRKSFRTLYNNLYGLKRPKALKLLGMEDDDPRPKGKKKMKKKKEEEIDIDVDDPEVSRFQYPFHELMVWAVLMKRQKMALFLWQRGEEAMAKALVACKLYKAMAHESSRSELVDDISQDLDNNSKDFGQLAYELLDQSYKHDEHMAMKLLTYELKNWSNSTCLKLAVAAKHRDFIAHTCSQMLLTDMWMGCLRVGKSNGLKVILGIIFPPAILLLDFRTGDDLSYQNSKDKEEVK----DKDDDTKSTKDGTVSMDATSKKGD--------------------------EEDGKKKQKRLPVGKKIYYFFNAPYTKFWFNTTAYLVYLMLYNYIILVKMERWPSLQEWIVISYIITLGLEKVRQILMSEPGKLKQKINVWLEEYWNITDLAAITTFLMGLLLRLQNEPYMGYGRVIYCVDIIFWYIRVLDIFGVNKYLGPYVMMIGKMMIDMLYFVVIMLVVLMSFGVARQAILHPDEEPTWRLARNIFYMPYWMIYGEVFADSIDRKTRIHIYAMEINPPCGENMYDEDGKKLPPCIPGAWLTPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQIWKFQRYQLIMTFHDRPVLPPPLIIFSHIYIVLKRLCCRCRKKQEGELDDRDHGLKLTLSAEELKSLYEFEEQNVEEYFREKEDEVQSSNDERIRITSQRVENMSMRLEEVNEREHTMKASLQTVDLRLAQLEEFSGRMMHALERLAGIDRCDLVRTRSGSSMAVDQS---GLLRRGSVTSADGYS-------------------------------LYRWHLD-------------AEERGDEVRGQGTERRSSIGITDLN-------PQHASSYGPTLDVLP-LRQRTHSSSSVDILISP-----------------------------------------------------------------------CESFPPQDGGQNS--QSPTRSSCQPTKDAHALLESRID-----------------------TAVSHPLERAQSLR-QYPNEAQNNSLSHENRSQSGT--------------------------------------------------LYVSMAQSKLS--SPGN---------------------------------TWASEPYGLQDQANRSPTLGRWPPRFDY----------KVHPSPFGLSPKTSSEKLRQVDDQDKED-------TSKESKRTNSHQAGSE-------------EKNKDEDEIQANNESTKTEEVDDKREELTDSDRLYVAEDRMYPALRSKSLNAN---PRKVKAAGD-------------------------------VLDKPRAASSVRDLAEAFEVNTNDYRPSRERSGTQT----------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A8DYE2-1", "uniprot_id": "TRPCG_DROME", "id": "A8DYE2-1", "name": "Transient receptor potential cation channel trpm", "aln": "MVVTDSPLAPHKYVRRISKDFSTVRRYSNTPAVVVGSFRASTSAFIAAESAAHLPTCSSPTTRTPVSTPRGIRRRQRMRKRSSVSSTLSKVLILNVRDLLKAHAGSEPLKEHQPRSWIETNFQKRECIKFIPCPKDDTKCCCGQAQITHQTIPGIESGSPG--------------DLWLPTKHTRPQPTDAYGTIEFQGGAHPTKAQYVRLSFDTRPELLVQLFTKEWNLELPKLLITVQGGKANFDLQAKLKKEIRKGLLKAAKTTGAWIFTGGTNTG--VTKQVGDALLLEGQQRTGRVVSIGIAPWGIVERNHELLGHNREVPCHSISSPRSKLAVLNNRHAYFLLVDNGTQAKYGAELILRRKLEKFISNLKLHPFTHSSTPVVCLVIEGGTNTIRAVLEYVTDSPPVPVVVCDGSGRAADLLAFVHKYASDGEEQPVLESMRDYLIGTIQKTFEVGLDQSEKLYQELLQCTRNKNLITVFRIQEKPEGEAQELDQTILTALFKSQHLSPPEQLSLALTWNRVDIARSEIFVYGQEWPNG----------------------------------------------------------ALDEAMMQALEHDRIDFVKLLLENGVSMKKFLTIPRLEELYNTKHGPANTLGYILRDVR-PHIPKGYIYTLHDIGLVINKLMGGAYRSYYTRRKFRPIYAKVMNSYANACRKSSTYQYQRYAGANSLSLVTG------LLPFTSEMALFEFPFNELLIWAVLTKRQQMALLMWTHGEEALAKSLVSCKLYKAMAHEAAEDDLDTEIYEELRSYAKEFESKGNKLLDFSYRQDAEKAQRLLTCELHSWSNQSCLSLAVAANHRALLAHPCSQVILADLWMGGLRTRKNTNFKVILGLAMPFYIRQLDFKSKEELQQMPQTEEEHLENQNLDNDDSDRSQPDAEALLADTYSVRDTKVHENGKVSLTDSDTAQFREFFNLSEYNEVKQHQPLRLKKKFYEFYTAPITKFWADSIAYMFFLIMFSFTVLVKMEQMPRWQEWYSIAYITTLGFEKVREIISSEPVAITHKFSVWAWNMWNPCDGAAIILFVIGLAFRFR-ENTMDIGRVIYCVDSIYWYLRILNILGVNKYLGPLVTMMGKMVKNMIYFVVLLAVVLMSFGVSRQAILYPNKQPTWSLIKEVTFQPYFMLYGEVFAGDID-------------PPCGEDPSQ------PGCVTGHWVTPITMSMYLLIANILLINLLIAVFNNIFNEVNSVSHQVWMFQRFTVVMEYQQKPVLPPPFIALCHFYSLLK----YCVRKAKGLEVQRDNGLKLFLEKDDLERLYDFEEECVEGFFHEQEIILNQSTDERVKNTTERVETMSQKIEDINQKENIQTATVQNIEFRLRKMEESSEQILSHLAVIHRFMSTHTAGADDLRGSTINIPGEMQRMRTISISDTEGGSGPGGNGGGGGGGGAIVPLGLGAGLNLNSLQVTTRRRFNRSLTEVRPDAYIFDEGTHFEVVPLPEEPDEVVKSREALNEQVVRKASMQSEADSDIYIPVSQRPSTCETVKRTPYVTVRQDTGASTESKDTLTPMGNNDDDQTLVGGDNSDDATPDINFEAARHRALRQRTVSLCRRNSETYSLTGADINRSHISLNQLASLSRRQMSLTQSEPDSDKDAPIAQGSAHPGKSVLHAKPSRNILLKLHSEYTSITDELESVCHMIASPTVSLPSNKASLDRPKTEMSRAEAAALLEKKHLKECEENDYMILEGLIESRGSIDASAQGFEIGVSIDYSHRYPLRRETAVELSPSKPSVDGDLMGGGEGGGAGGGDSSDTSGAGSCGAMVGISSGFQLKNERPWQRNSSMEQQTYPSPLVPTRATSDFLNPPYEGRLFKKSSESLQKNSSTETDYSAHPYRFIKQSSNETNTSLTGSYNVDTPSLTAEPSLDAGDSHSATGISISVGAVGGTATARYQPIRTASVGAADGRRLREESSSSLDLSSSGPVTMQAAPAPPVRPMLLKKQFSVDQGKPSQTAAEAVPQTPEAAQAGQAKLISTLKPQPFASKLGMNVLKESSSSTDESVGSSAKSSNPALSIPQISTHLVQDEIAKLSSNIKSSTESEKDPPFNETMC", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: .:**** *:.:* :. : . : * :***:. ***:** :*****.: .** *:*:*:**:*: *::*:.*:*:****.***:*:** .*::*.***: : ***:*** **********..** * :***** ...: *:: :*******:**.:.:*:*:: :::*.* ***:**** *::*:*.**** .*****: *** ***.** *::. ...*:* *::***.*.: *** : :.**:***:*******:*:::*.***..:. : :*:*: *: ******: . *: ::: :::* ::::*:**** .: : *::: :*****:*. : *.*:******:*********:***.* .** :*::**::** **:******:****.:::*************: ** *** ::***: ::* .* :* *****:: *******. ***:.**.:* :: . . * : : .. . . : . :: *::**:**::**** ***:**:::* :***.:**:**:**********::..:* :* ::* . :*:* . . :*** **::* . * :*** **:.***.:**.*****:** ::**.***::*:*:*** ** *. .:***:*: :* * *:*:: :::. ..::*. : :::: : . * * : *::: : : .*: *:.** .*** : :*: :*:::.: :**:*: * *** *:** :*.:**:*:*: *** :.:*:.** : ** * .** *::* :*:: : *. ******** * **:*:*:*:******** * *:***: :*:****:: ********:*****:*:::*:* * ::: : **:*:******..** *****: : * *:.* *:** *: ***:*****:********* * **:*:*:*:* ***: ::* ::::******:* :.*:* :: * :* :* :**.**** *. ::*: *::***: *: .*:*:* :.*.***:: *::***.** ::*::*::* .:::*.:::** ::** * ::: * : : . : . . : . :* *:..::* * * ::: * * . . .. . : : : * . : . . : . : *: ... : : .: . . *.. . * : . : . : . : : : . : ..: ... . * : : * **. * . :. :. *. * . :* .. ", "identical_positions": 539, "similar_positions": 452, "identity": "25.33%" }, { "cls_id": "homologset.agr.MGI:1330307", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A098-1", "uniprot_id": "D4A098_RAT", "id": "D4A098-1", "name": "", "aln": "TMEGQAVPGVGDWEIDVESLELEEDGCGTPLRATP-QEPSPSTADGEEDEDEEEEDEDAEDEGEGEDSSASPEVPGRPEQPGGLAPRPPPAAQALPAAAVVPERGVTAGGGAEPRKLSRTPKCARCRNHGVVSCLKGHKRFCRWRDCQCANCLLVVERQRVMAAQVALRRQQATEDKKGLSGKQNNFDRKAVYQRQVRAPSLLAKSILEG---YRPMTAAETYLGGTLPLPPPVSDRMRKRRAFADKELENIMLEREYKEREMLETSQAAALFLPNRMVPGPEYSSYKGAFSPSAGELPSKDFCNFLPTCLDLTMQYSGSGNMELISSNVSVATTYRQYPLSSRFLVWPKCGPISDTLLYQQYLLNATTSVQALKPGAGWDLKGTRVQDGLSAEHDGMPPKPEGSLVLPQLSEVPTSRTDLQAHQAVPERSAFSPPSRNFSPIVDMDCLAAQGHVLTKISKENTRYPLPLKRNPFHSVFQPTLNDKSGPELKAPFVKEAFEETPKKHRECLVKENPKYTFTIDRCAKDLFVAKQVGTKLSVNEPLSFSVESILKRPSSAVTPVSQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BG36-1", "uniprot_id": "DMRT2_MOUSE", "id": "Q8BG36-1", "name": "Doublesex- and mab-3-related transcription factor 2", "aln": "MTEGQAVPGVGDWEIDVESLDLEEDSCGTPLRATPPQEPSPAAADGEEDEDEEEEDEDVEDEGDGEEPGVSSEVPGRPEQPGGLAPRPPPAAQALPAAAAAPERGATAGGGAEPRKLSRTPKCARCRNHGVVSCLKGHKRFCRWRDCQCANCLLVVERQRVMAAQVALRRQQATEDKKGLSGKQNNFDRKAVYQRQVRAPSLLAKSILEG---YRPMT-AETYLGGTLPLPPPVSDRMRKRRAFADKELENIMLEREYKEREMLETSQAAALFLPNRMVPGPEYSSYKGTYSPTAGELPSKDFCNFLPTCLDLTMQYSGSGNMELISSNVSVATTYRQYPLSSRFLVWPKCGPISDTLLYQQYLLNATTSVQALKPGTGWDLKGTRVQDGLSAEQDMMPPKLEGSLVLPHLPEVPASRTDLQVHQVVPERSAFSPPGRNFSPIVDMDCLAAQGHVLTKLSKENTRPSLPLKTNPFHSVFQQTLSDKSGPELNAPFVKEAFEETPKKHRECLVKESQKYTFTIDRCAKDLFVAKQVGTKLSANEPLSFSVESILKRPSSAVTHVSQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y5R5-1", "uniprot_id": "DMRT2_HUMAN", "id": "Q9Y5R5-1", "name": "Doublesex- and mab-3-related transcription factor 2", "aln": "MADPQAGSAAGDWEIDVESLELEEDVCGAPRSTPPGPSPPPADGDCEDDEDDDGVDEDAEEEGDGEEAGASPGMPGQPEQRGGPQPRPPLAPQASPAGTGPRERCTPAGGGAEPRKLSRTPKCARCRNHGVVSCLKGHKRFCRWRDCQCANCLLVVERQRVMAAQVALRRQQATEDKKGLSGKQNNFERKAVYQRQVRAPSLLAKSILEG---YRPIP-AETYVGGTFPLPPPVSDRMRKRRAFADKELENIMLEREYKEREMLETSQAAALFLPNRMVPGPDYNSYKSAYSPSPVEPPSKDFCNFLPTCLDLTMQYSGSGNMELISSNVSVATTYRQYPLSSRFLVWPKCGPISDTLLYQQCLLNATTSVQALKPGASWDLKGARVQDGLSAEQDMMPSKLEGSLVLPHTPEIQTTRSDLQGHQAVPERSAFSPPRRNFSPIVDTDSLAAQGHVLTKISKENTRHPLPLRHNPFHSLFQQTLTDKSGPELKTPFVKEAFEETPKKHRECLVKDNQKYTFTIDRCAKDLFVAKQVGTKLSVNEPLSFSVESILKRPSSAITRVSQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VYE0-1", "uniprot_id": "Q9VYE0_DROME", "id": "Q9VYE0-1", "name": "", "aln": "MHFDETRSPNKDVRIGKSQRLAANGRQGTDPESDPLHARCVVPHASTPRGRRIPWGHNDDDD-DGNHLTLPDSLTATSSCGCQCLNVRAPFHILLVDQQARMSKDASVRICQRERRLLRTPKCARCRNHGVISCVKGHKRLCRWRECCCPNCQLVVDRQRVMAAQVALRRQQTMEALEATASSTKSTG--------VTTASANNSSSSEGEDSLS-------------------------------------------------------------STSPPPAHSHPHSHSHPTS------------------------------CVSNSSSSSATRQALMAQKRIYKQRLR------SLQQSTLHITAAMEEYKQ--RFPTFSSPLMERMRKRRAFADPELN------HVMEATLGGNALYFATVAAAAAACAP-------------VHQEQHIYHPMP-----PTIPLTIPPTN------------PAMTTPAVTTASTGSGKKP------------------------------------KLSFSIESIMGIST--------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: . * .*. .. :. *: : * ..: ::: :*:. . :.. .. . .: ... . *:* *************:**:*****:****:* *.** ***:***************: * :. :.. :. * :.* .* ** * * :. :. *:. ** * ::: ** ::.: : : ** *: *:::: * : .: : : : .: .: : : * . * ... :* :* : : *: :. .:** * : * :.:* *. * : ** ****:***: .: ", "identical_positions": 93, "similar_positions": 106, "identity": "16.46%" }, { "cls_id": "homologset.agr.MGI:1330309", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JWA0-1", "uniprot_id": "A0A0G2JWA0_RAT", "id": "A0A0G2JWA0-1", "name": "", "aln": "MSYQQQQCKQPCQPPPVCPPPKCPEPCPPPKCPEPCPPPKCP-EPCPVPCPPPSYQQKCPPVQPHPPCQQKCPPKSK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70560-1", "uniprot_id": "SPR2I_MOUSE", "id": "O70560-1", "name": "Small proline-rich protein 2I", "aln": "MSYQQQQCKQPCQPPPVCPPKKCPEPCPPPQCPEPCPPPKCP-EPCPESCPPPSYQQKCPPVQPPPPCQQKCPPKSK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P35326-1", "uniprot_id": "SPR2A_HUMAN", "id": "P35326-1", "name": "Small proline-rich protein 2A", "aln": "MSYQQQQCKQPCQPPPVCPTPKCPEPCPPPKCPEPCPPPKCP-QPC----PPQQCQQKYPPVTPSPPCQSKYPPKSK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P35325-1", "uniprot_id": "SPR2B_HUMAN", "id": "P35325-1", "name": "Small proline-rich protein 2B", "aln": "MSYQQQQCKQPCQPPPVCPTPKCPEPCPPPKCPEPCPPPKCP-QPC----PPQQCQQKYPPVTPSPPCQPKYPPKSK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P22532-1", "uniprot_id": "SPR2D_HUMAN", "id": "P22532-1", "name": "Small proline-rich protein 2D", "aln": "MSYQQQQCKQPCQPPPVCPTPKCPEPCPPPKCPEPCPSPKCP-QPC----PPQQCQQKYPPVTPSPPCQPKCPPKSK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P22531-1", "uniprot_id": "SPR2E_HUMAN", "id": "P22531-1", "name": "Small proline-rich protein 2E", "aln": "MSYQQQQCKQPCQPPPVCPTPKCPEPCPPPKCPEPCPPPKCP-QPC----PPQQCQQKCPPVTPSPPCQPKCPPKSK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q96RM1-1", "uniprot_id": "SPR2F_HUMAN", "id": "Q96RM1-1", "name": "Small proline-rich protein 2F", "aln": "MSYQQQQCKQPCQPPPVCPAPKCPEPCPPPKCPEPCPPSKCP-QSC----PPQQCQQKCPPVTPSPPCQPKCPPKSK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9BYE4-1", "uniprot_id": "SPR2G_HUMAN", "id": "Q9BYE4-1", "name": "Small proline-rich protein 2G", "aln": "MSYQQQQCKQPCQPPPVCPTPKCPEPCPPPKCPEPYLPPPCPPEHC----PPPPCQDKCPPVQPYPPCQQKYPPKSK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*******************. *********:**** .. ** : * ** *:* *** * **** * *****", "identical_positions": 53, "similar_positions": 6, "identity": "68.83%" }, { "cls_id": "homologset.agr.MGI:1330312", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q27W02-1", "uniprot_id": "MGN_RAT", "id": "Q27W02-1", "name": "Protein mago nashi homolog", "aln": "-MESDFYLRYYVGHKGKFGHEFLEFEFRPDGKLRYANNSNYKNDVMIRKEAYVHKSVMEELKRIIDDSEITKEDDALWPPPDRVGRQELEIVIGDEHISFTTSKIGSLIDVNQSKDPEGLRVFYYLVQDLKCLVFSLIGLHFKIKPI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P61327-1", "uniprot_id": "MGN_MOUSE", "id": "P61327-1", "name": "Protein mago nashi homolog", "aln": "-MESDFYLRYYVGHKGKFGHEFLEFEFRPDGKLRYANNSNYKNDVMIRKEAYVHKSVMEELKRIIDDSEITKEDDALWPPPDRVGRQELEIVIGDEHISFTTSKIGSLIDVNQSKDPEGLRVFYYLVQDLKCLVFSLIGLHFKIKPI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P61326-1", "uniprot_id": "MGN_HUMAN", "id": "P61326-1", "name": "Protein mago nashi homolog", "aln": "-MESDFYLRYYVGHKGKFGHEFLEFEFRPDGKLRYANNSNYKNDVMIRKEAYVHKSVMEELKRIIDDSEITKEDDALWPPPDRVGRQELEIVIGDEHISFTTSKIGSLIDVNQSKDPEGLRVFYYLVQDLKCLVFSLIGLHFKIKPI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q566Y8-1", "uniprot_id": "MGN_DANRE", "id": "Q566Y8-1", "name": "Protein mago nashi homolog", "aln": "MSTSDFYLRYYVGHKGKFGHEFLEFEFRPDGKLRYANNSNYKNDVMIRKEAYVHKSVMEELKRIIDDSEITKEDDALWPPPDRVGRQELEIVIGDEHISFTTSKIGSLIDVNQSKDPEGLRVFYYLVQDLKCLVFSLIGLHFKIKPI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P49028-1", "uniprot_id": "MGN_DROME", "id": "P49028-1", "name": "Protein mago nashi", "aln": "MSTEDFYLRYYVGHKGKFGHEFLEFEFRPDGKLRYANNSNYKNDTMIRKEAFVHQSVMEELKRIIIDSEIMQEDDLPWPPPDRVGRQELEIVIGDEHISFTTSKTGSLVDVNRSKDPEGLRCFYYLVQDLKCLVFSLIGLHFKIKPI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .****************************************.******:**:********** **** :*** *************************** ***:***:******** *************************", "identical_positions": 131, "similar_positions": 7, "identity": "89.12%" }, { "cls_id": "homologset.agr.MGI:1330343", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JUT6-1", "uniprot_id": "A0A0G2JUT6_RAT", "id": "A0A0G2JUT6-1", "name": "", "aln": "MSYQQQQCKQPCQPPPVCPPPKCPEPCPPPKCPEPCPPP------------------KCPEPCPPPKCPEPCPPPKCTEPCPPPSYQQKCPPVQPPPTCQQKCPPKSK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D4A802-1", "uniprot_id": "D4A802_RAT", "id": "D4A802-1", "name": "", "aln": "MSYQQQQCKQPCQPPPVCQPPKCPEPCPPPKCPEPCPPP------------------KCPEPC--------------FEPCPPPSHQQKCPPVQPPPPCQQKCPPKSK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70559-1", "uniprot_id": "SPR2H_MOUSE", "id": "O70559-1", "name": "Small proline-rich protein 2H", "aln": "MSYQQQQCKQPCQPPPVCPPPQCPEPCPPPKCPEPCPPPKCTEPCPPPKCPEPCPPPKCPEPCPPPKCPEPCPPPKCTEPCPPPSYQQKCPSVQPSPPCQQKCPPKNK", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****************** **:***************** ****** *******:*****.***.*.********.*", "identical_positions": 68, "similar_positions": 6, "identity": "62.96%" }, { "cls_id": "homologset.agr.MGI:1330346", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JWA0-1", "uniprot_id": "A0A0G2JWA0_RAT", "id": "A0A0G2JWA0-1", "name": "", "aln": "MSYQQQQCKQPCQPPPVCPPPKCPEPCPPPKCPEPCPPPKCPEPCPVPCPPPSYQQKCPPVQPHPPCQQKCPPKSK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70556-1", "uniprot_id": "SPR2E_MOUSE", "id": "O70556-1", "name": "Small proline-rich protein 2E", "aln": "MSYQQQQCKQPCQPPPVCPPKKCPEPCPHPQCPEPCPPPKCPEPCPEPCPPPSYQQKCPPVQPPPPCQQKCPPKSK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P35326-1", "uniprot_id": "SPR2A_HUMAN", "id": "P35326-1", "name": "Small proline-rich protein 2A", "aln": "MSYQQQQCKQPCQPPPVCPTPKCPEPCPPPKCPEPCPPPKCPQ----PCPPQQCQQKYPPVTPSPPCQSKYPPKSK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P35325-1", "uniprot_id": "SPR2B_HUMAN", "id": "P35325-1", "name": "Small proline-rich protein 2B", "aln": "MSYQQQQCKQPCQPPPVCPTPKCPEPCPPPKCPEPCPPPKCPQ----PCPPQQCQQKYPPVTPSPPCQPKYPPKSK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P22532-1", "uniprot_id": "SPR2D_HUMAN", "id": "P22532-1", "name": "Small proline-rich protein 2D", "aln": "MSYQQQQCKQPCQPPPVCPTPKCPEPCPPPKCPEPCPSPKCPQ----PCPPQQCQQKYPPVTPSPPCQPKCPPKSK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P22531-1", "uniprot_id": "SPR2E_HUMAN", "id": "P22531-1", "name": "Small proline-rich protein 2E", "aln": "MSYQQQQCKQPCQPPPVCPTPKCPEPCPPPKCPEPCPPPKCPQ----PCPPQQCQQKCPPVTPSPPCQPKCPPKSK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q96RM1-1", "uniprot_id": "SPR2F_HUMAN", "id": "Q96RM1-1", "name": "Small proline-rich protein 2F", "aln": "MSYQQQQCKQPCQPPPVCPAPKCPEPCPPPKCPEPCPPSKCPQ----SCPPQQCQQKCPPVTPSPPCQPKCPPKSK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9BYE4-1", "uniprot_id": "SPR2G_HUMAN", "id": "Q9BYE4-1", "name": "Small proline-rich protein 2G", "aln": "MSYQQQQCKQPCQPPPVCPTPKCPEPCPPPKCPEPYLPPPCPP---EHCPPPPCQDKCPPVQPYPPCQQKYPPKSK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*******************. ******* *:**** .. ** *** *:* *** * **** * *****", "identical_positions": 52, "similar_positions": 5, "identity": "68.42%" }, { "cls_id": "homologset.agr.MGI:1330347", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P35326-1", "uniprot_id": "SPR2A_HUMAN", "id": "P35326-1", "name": "Small proline-rich protein 2A", "aln": "MSYQQQQCKQPCQPPPVCPTPKCPEPCPPPKCPEPCPPPKCP-QPCPPQQC------------------QQKYPPVTPSPPCQSKYPPKSK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P35325-1", "uniprot_id": "SPR2B_HUMAN", "id": "P35325-1", "name": "Small proline-rich protein 2B", "aln": "MSYQQQQCKQPCQPPPVCPTPKCPEPCPPPKCPEPCPPPKCP-QPCPPQQC------------------QQKYPPVTPSPPCQPKYPPKSK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P22532-1", "uniprot_id": "SPR2D_HUMAN", "id": "P22532-1", "name": "Small proline-rich protein 2D", "aln": "MSYQQQQCKQPCQPPPVCPTPKCPEPCPPPKCPEPCPSPKCP-QPCPPQQC------------------QQKYPPVTPSPPCQPKCPPKSK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P22531-1", "uniprot_id": "SPR2E_HUMAN", "id": "P22531-1", "name": "Small proline-rich protein 2E", "aln": "MSYQQQQCKQPCQPPPVCPTPKCPEPCPPPKCPEPCPPPKCP-QPCPPQQC------------------QQKCPPVTPSPPCQPKCPPKSK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q96RM1-1", "uniprot_id": "SPR2F_HUMAN", "id": "Q96RM1-1", "name": "Small proline-rich protein 2F", "aln": "MSYQQQQCKQPCQPPPVCPAPKCPEPCPPPKCPEPCPPSKCP-QSCPPQQC------------------QQKCPPVTPSPPCQPKCPPKSK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0G2JUT6-1", "uniprot_id": "A0A0G2JUT6_RAT", "id": "A0A0G2JUT6-1", "name": "", "aln": "MSYQQQQCKQPCQPPPVCPPPKCPEPCPPPKCPEPCPPPKCP-EPCPPPKCPEPCPPPKCTEPCPPPSYQQKCPPVQPPPTCQQKCPPKSK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3ZAR3-1", "uniprot_id": "D3ZAR3_RAT", "id": "D3ZAR3-1", "name": "", "aln": "MSYQQQQCKQPCQPPPVCPTPKCPEPCPPPKCPEPCPPPKCP-ESCPPPKCPEPCPPP---------SYQQKCPPVQPPPTCQQKCPPKSK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70555-1", "uniprot_id": "SPR2D_MOUSE", "id": "O70555-1", "name": "Small proline-rich protein 2D", "aln": "MSYQQQQCKQPCQPPPVCPPKKCPEPCPPLKCPEPCPPPKCP-EPCPPPKCPEPCPEP-----CPPPSCQQKCPPAQPPPPCQQKCPPKSK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BYE4-1", "uniprot_id": "SPR2G_HUMAN", "id": "Q9BYE4-1", "name": "Small proline-rich protein 2G", "aln": "MSYQQQQCKQPCQPPPVCPTPKCPEPCPPPKCPEPYLPPPCPPEHCPPPPC------------------QDKCPPVQPYPPCQQKYPPKSK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*******************. ******** ***** .. ** : *** * *:* **. * *.** * *****", "identical_positions": 52, "similar_positions": 7, "identity": "57.14%" }, { "cls_id": "homologset.agr.MGI:1330348", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZAR3-1", "uniprot_id": "D3ZAR3_RAT", "id": "D3ZAR3-1", "name": "", "aln": "MSYQQQQCKQPCQPPPVCPTPKCPEPCPPPKCPEPCPPPKCPESCPPPKCPEPCPPPSYQQKCPPVQPPPTCQQKCPPKSK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70558-1", "uniprot_id": "SPR2G_MOUSE", "id": "O70558-1", "name": "Small proline-rich protein 2G", "aln": "MSFQEQQCKQPCQPPPVCPPPKCPEPCPLPKCPEPCPPPKCPEPCP-----EPCLPSPCQQKCPPVQTPPPCQQKCPPKSK", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:*:**************.******** **************.** *** *.. ********.**.**********", "identical_positions": 65, "similar_positions": 8, "identity": "80.25%" }, { "cls_id": "homologset.agr.MGI:1330349", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JUT6-1", "uniprot_id": "A0A0G2JUT6_RAT", "id": "A0A0G2JUT6-1", "name": "", "aln": "MSYQQQQCKQPCQPPPVCPPPKCPEPCPPPKCPEPCPPPKCPEPCPPPKCPEPCPPPKCTEPCPPPSYQQKCPPVQPPPTCQQKCPPKSK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3ZAR3-1", "uniprot_id": "D3ZAR3_RAT", "id": "D3ZAR3-1", "name": "", "aln": "MSYQQQQCKQPCQPPPVCPTPKCPEPCPPPKCPEPCPPPKCPESCPPPKCPEPCPPP---------SYQQKCPPVQPPPTCQQKCPPKSK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70557-1", "uniprot_id": "SPR2F_MOUSE", "id": "O70557-1", "name": "Small proline-rich protein 2F", "aln": "MSYQEQQCKQPCQPPPVCPPPKCPEPCSPSVCPEPCPPPKCPEPCP-----EPCPPP---------SFQQKCPPVQPPPPCQQKCPPKSK", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****:**************.*******.*. ************.** ****** *:***********.**********", "identical_positions": 68, "similar_positions": 7, "identity": "75.56%" }, { "cls_id": "homologset.agr.MGI:1330352", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZQA8-1", "uniprot_id": "D3ZQA8_RAT", "id": "D3ZQA8-1", "name": "", "aln": "MSYHQQQCKQPCQPPPVCLPPKCPEPCPPPVCPEPCRPPVC---------PEPCPPPVCCEPCPPPVCCEPCPPQTWQPNCPPVQTPPCQQKCPPKNK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70554-1", "uniprot_id": "SPR2B_MOUSE", "id": "O70554-1", "name": "Small proline-rich protein 2B", "aln": "MSYYQQQCKQPCQPPPVCPPPKCPEPCPPPKCPEPCPPPVCCEPCPPPKCPEPCPPPVCCEPCPPPVCCEPCPPQPWQPKCPPVQFPPCQQKCPPKNK", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***:************** *********** ***** **** *************************.***:***** ************", "identical_positions": 82, "similar_positions": 3, "identity": "83.67%" }, { "cls_id": "homologset.agr.MGI:1330587", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q60967-1", "uniprot_id": "PAPS1_MOUSE", "id": "Q60967-1", "name": "Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1", "aln": "----------------------MEIPGSLCKKVKLSNNAQNWGMQRATNVTYQAHHVSRNKRGQVVGTRGGFRGCTVWLTGLSGAGKTTVSMALEEYLVCHGIPCYTLDGDNIRQGLNKNLGFSPEDREENVRRIAEVAKLFADAGLVCITSFISPYTQDRNNARQIHEGASLPFFEVFVDAPLHVCEQRDVKGLYKKARAGEIKGFTGIDSEYEKPEAPELVLKTDSCDVNDCVQQVVELLQERDIVP---VDASYEVKELYVPENKLHLAKTDAEALPALKINKVDMQWVQVLAEGWATPLNGFMREREYLQCLHFDCLLDGG----VINLSVPIVLTATHEDKERLDGCTAFALVYEGRRVAILRNPEFFEHRKEERCARQWGTTCKNHPYIKMVLEQGDWLIGGDLQVLDRIYWNDGLDQYR-LTPTELKQKFKDMNADAVFAFQLRNPVHNGHALLMQDTHKQLLERGYRRPVLLLHPLGGWTKDDDVPLMWRMKQHAAVLEEGILDPETTVVAIFPSPMMYAGPTEVQWHCRARMVAGANFYIVGRDPAGMPHPETG----KDLYEPTHGAKVLTMAPGLITLEIVPFRVAAYNKKKKRMDYYDSEHHEDFEFISGTRMRKLAREGQKPPEGFMAPKAWTVLVEYYKSLEKA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K0L0-1", "uniprot_id": "A0A0G2K0L0_RAT", "id": "A0A0G2K0L0-1", "name": "Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1", "aln": "----------------------MEIPGSLCKKVKLSNNAQNWGMQRATNVTYQAHHVSRNKRGQVVGTRGGFRGCTVWLTGLSGAGKTTVSMALEEYLVCHGIPCYTLDGDNIRQGLNKNLGFSPEDREENVRRIAEVAKLFADAGLVCITSFISPYTQDRNNARQIHEGASLPFFEVFVDAPLHVCEQRDVKGLYKKARAGEIKGFTGIDSEYEKPEAPELVLKTDSCDVNDCVQQVVELLQERDIVP---VDASYEVKELYVPENKLHLAKTDAEALPALKINKVDMQWVQVLAEGWATPLNGFMREREYLQCLHFDCLLDGG----VINLSVPIVLTATQEDKERLDGCTAFALVYEGRRVAILRNPEFFEHRKEERCARQWGTTCRSHPYIKMILEQGDWLIGGDLQVLDRIYWNDGLDQYR-LTPAELKQKFKDMNADAVFAFQLRNPVHNGHALLMQDTHKQLLERGYRRPVLLLHPLGGWTKDDDVPLMWRMKQHAAVLEEGILNPETTVVAIFPSPMMYAGPTEVQWHCRARMVAGANFYIVGRDPAGMPHPETG----KDLYEPTHGAKVLTMAPGLITLEIVPFRVAAYNKKKKRMDYYDSDHHEDFEFISGTRMRKLAREGQKPPEGFMAPKAWTVLVEYYKSLEKA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O43252-1", "uniprot_id": "PAPS1_HUMAN", "id": "O43252-1", "name": "Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1", "aln": "----------------------MEIPGSLCKKVKLSNNAQNWGMQRATNVTYQAHHVSRNKRGQVVGTRGGFRGCTVWLTGLSGAGKTTVSMALEEYLVCHGIPCYTLDGDNIRQGLNKNLGFSPEDREENVRRIAEVAKLFADAGLVCITSFISPYTQDRNNARQIHEGASLPFFEVFVDAPLHVCEQRDVKGLYKKARAGEIKGFTGIDSEYEKPEAPELVLKTDSCDVNDCVQQVVELLQERDIVP---VDASYEVKELYVPENKLHLAKTDAETLPALKINKVDMQWVQVLAEGWATPLNGFMREREYLQCLHFDCLLDGG----VINLSVPIVLTATHEDKERLDGCTAFALMYEGRRVAILRNPEFFEHRKEERCARQWGTTCKNHPYIKMVMEQGDWLIGGDLQVLDRVYWNDGLDQYR-LTPTELKQKFKDMNADAVFAFQLRNPVHNGHALLMQDTHKQLLERGYRRPVLLLHPLGGWTKDDDVPLMWRMKQHAAVLEEGVLNPETTVVAIFPSPMMYAGPTEVQWHCRARMVAGANFYIVGRDPAGMPHPETG----KDLYEPSHGAKVLTMAPGLITLEIVPFRVAAYNKKKKRMDYYDSEHHEDFEFISGTRMRKLAREGQKPPEGFMAPKAWTVLTEYYKSLEKA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q02196-1", "uniprot_id": "KAPS_YEAST", "id": "Q02196-1", "name": "Adenylyl-sulfate kinase", "aln": "----------------------------------MATN-----ITWHPNLTYDERKALRKQDG-----------CTIWLTGLSASGKSTIACALEQLLLQKNLSAYRLDGDNIRFGLNKDLGFSEKDRNENIRRISEVSKLFADSCAISITSFISPYRVDRDRARELHKEAGLKFIEIFVDVPLEVAEQRDPKGLYKKAREGVIKEFTGISAPYEAPKAPELHLRTDQKTVEECATIIYEYLISEKII-------------------RKHL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q8IQV1-1", "uniprot_id": "Q8IQV1_DROME", "id": "Q8IQV1-1", "name": "", "aln": "MFTRCANSLGLYHNNINNNNSACCAASPKRSCLPSVEKPEDACLQVATNVTEQKHHVTRETRGKNLGLCRGFRGCTVWLTGLSGAGKTSIAFELEAYLVSRGIPAYGLDGDNIRTGLNKNLGFTPADREENIRRVGEVAKLFADSGVVAICSFVSPFADDREMARKIHKDAGLKFYEIFVDTPLDVCETRDVKGLYKKAREGVIKGFTGITQEYERPQMPELVVNTHGYTVRESTQKLVTLLEQEGIIPRSLRDVDLLPELYPSESIATEALRHEAESLQAIEISTVELQWVQVLAEGWAYPLRGFMREDEYLQTLHFNTLQSGMDGSYRENHSVPIVLSATQADKDRLDGCSSLTLKYQGKAVAILRRPEFYFQRKEERLARQFGTSNPNHPYSKQVYESGDYLVGGDLAVIERIRWEDGLDQYR-LTPNELRRRFKELNADAIFAFQLRNPIHNGHALLMQDTRRQLLERGFKQPVLLLHPLGGWTKDDDVPLDVRMKQHQAVLDAGVLRREDTVLAIFPSPMMYAGPTEVQWHAKARMNAGANFYIVGRDPAGMPHPAKETYPDGNLYDATHGARVLKMAQGLDSMEILPFRVAAYDKSASRMAFFEPKRKDEFEFISGTKMRTLAKTGASPPDGFMEPEAWRILATYYQNLPQS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P08536-1", "uniprot_id": "MET3_YEAST", "id": "P08536-1", "name": "Sulfate adenylyltransferase", "aln": "--------------------------------MPAPHGGILQDLIARDALKKNELLSEAQSSDILVWNLTPRQLCDIELI-LNGGFSPLTGFLNENDYSSVVTDSRLADGTLWTIPITLDVDEAFAN---QIKPDTRIALFQDDEIPIAILTVQDVYKPNKTIEAEKVFRGDP--EHPAISYLFNVAGDYYVGGSLEAIQLPQHYDYPGLR---KTPAQLRLEFQSRQWDRVVAFQTRNPMHRAHRELT----------------VRAAREANAKVLIHPVVGLTKPGDIDHHTRVRVYQEIIKRYPNGIAFLSLLPLAMRMSGD-------------------------------------------------------------REAVWHAIIRKNYGASHFIVGRDHAGPGKN--SKGVDFYGPYDAQELVESYKHELDIEVVPFRMVTYLPDEDRYAPIDQIDTTKTRTLNISGTELRRR--LRVGGEIPEWFSYPEVVKILRESNPPRPKQGFSIVLGNSLTVS------REQLSIALLSTFLQFGGGRY------------YKIFEHNNKTELLSLIQDFIGSGSGLIIPNQWEDDKD-----SVVGKQNVYLLDTSSSADIQLESADEPISHIVQKVVLFLEDNGFFVF--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :. : : . * : * *... .. . * . ** :. ::. : : ::: .:: : * :.* :. . : :: : .. . :. :.*. * : : :.*: : * .* ..: . . : . ", "identical_positions": 13, "similar_positions": 59, "identity": "1.98%" }, { "cls_id": "homologset.agr.MGI:1330805", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LW77-1", "uniprot_id": "F1LW77_RAT", "id": "F1LW77-1", "name": "small monomeric GTPase", "aln": "MASEMESSLEVSFSSSCAVSGASGCLPPARSRIFKIIVIGDSNVGKTCLTYRFCAGRFPDRTEATIGVDFRERAVDIDGERIKIQLWDTAGQERFRKSMVQHYYRNVHAVVFVYDMTNMASFHSLPSWIEECKQHLLANDIPRILVGNKCDLRSAIQVPTDLAQKFADTHSMPLFETSAKNPNDNDHVEAIFMTLAHKLKSHKPLMLSQLPDNRISLKPETKPAVTCWC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35963-1", "uniprot_id": "RB33B_MOUSE", "id": "O35963-1", "name": "Ras-related protein Rab-33B", "aln": "MTSEMESSLEVSFSSSCAVSGASGCLPPARSRIFKIIVIGDSNVGKTCLTYRFCAGRFPDRTEATIGVDFRERAVDIDGERIKIQLWDTAGQERFRKSMVQHYYRNVHAVVFVYDMTNMASFHSLPAWIEECKQHLLANDIPRILVGNKCDLRSAIQVPTDLAQKFADTHSMPLFETSAKNPNDNDHVEAIFMTLAHKLKSHKPLMLSQLPDNRISLKPETKPAVTCWC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H082-1", "uniprot_id": "RB33B_HUMAN", "id": "Q9H082-1", "name": "Ras-related protein Rab-33B", "aln": "MAEEMESSLEASFSSSGAVSGASGFLPPARSRIFKIIVIGDSNVGKTCLTYRFCAGRFPDRTEATIGVDFRERAVEIDGERIKIQLWDTAGQERFRKSMVQHYYRNVHAVVFVYDMTNMASFHSLPSWIEECKQHLLANDIPRILVGNKCDLRSAIQVPTDLAQKFADTHSMPLFETSAKNPNDNDHVEAIFMTLAHKLKSHKPLMLSQPPDNGIILKPEPKPAMTCWC", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:.*******.***** ******* **************************************************:**************************************************:********************************************************************************** *** * ****.***:****", "identical_positions": 217, "similar_positions": 7, "identity": "94.76%" }, { "cls_id": "homologset.agr.MGI:1330806", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O08691-1", "uniprot_id": "ARGI2_MOUSE", "id": "O08691-1", "name": "Arginase-2, mitochondrial", "aln": "------MFLRSSASRLLHGQIPCVLTRSVHSVAIVGAPFSRGQKKLGVEYGPAAIREAGLLKRLSRLGCHLK---DFGDLSFT---NVPQDDPYN--NLVVY------PRSVGLANQELAEVVSRAVSGGYSCVTMGGDHSLAIGTIIGHARHRPDLCVIWVDAHADINTPLTTVSGNIHGQPLSFLIKELQDKVPQLPG-FSWIKPCLSPPNIVYIGLRDVEPPEHFILKNYDIQYFSMREIDRLGIQKVMEQTFDRLIGKR--QRPIHLSFDIDAFDPKLAPATGTPVVGGLTYREGVYITEEIHNTGLLSALDLVEVNPHLATSEEEAKATARLAVDVIASSFGQTREGGHIVYDHLPTPSSPHESENEECVRI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O08701-1", "uniprot_id": "ARGI2_RAT", "id": "O08701-1", "name": "Arginase-2, mitochondrial", "aln": "------MFLRSSVSRLLHGQIPCALTRSVHSVAVVGAPFSRGQKKKGVEYGPAAIREAGLLKRLSMLGCHIK---DFGDLSFT---NVPKDDPYN--NLVVY------PRSVGIANQELAEVVSRAVSGGYSCVTLGGDHSLAIGTISGHARHHPDLCVIWVDAHADINTPLTTVSGNIHGQPLSFLIRELQDKVPQLPG-FSWIKPCLSPPNLVYIGLRDVEPAEHFILKSFDIQYFSMRDIDRLGIQKVMEQTFDRLIGKR--KRPIHLSFDIDAFDPKLAPATGTPVVGGLTYREGLYITEEIHSTGLLSALDLVEVNPHLATSEEEAKATASLAVDVIASSFGQTREGGHIAYDHLPTPSSPHESEKEECVRI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P78540-1", "uniprot_id": "ARGI2_HUMAN", "id": "P78540-1", "name": "Arginase-2, mitochondrial", "aln": "------MSLRGSLSRLLQTRVHSILKKSVHSVAVIGAPFSQGQKRKGVEHGPAAIREAGLMKRLSSLGCHLK---DFGDLSFT---PVPKDDLYN--NLIVN------PRSVGLANQELAEVVSRAVSDGYSCVTLGGDHSLAIGTISGHARHCPDLCVVWVDAHADINTPLTTSSGNLHGQPVSFLLRELQDKVPQLPG-FSWIKPCISSASIVYIGLRDVDPPEHFILKNYDIQYFSMRDIDRLGIQKVMERTFDLLIGKR--QRPIHLSFDIDAFDPTLAPATGTPVVGGLTYREGMYIAEEIHNTGLLSALDLVEVNPQLATSEEEAKTTANLAVDVIASSFGQTREGGHIVYDQLPTPSSPDESENQARVRI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P00812-1", "uniprot_id": "ARGI_YEAST", "id": "P00812-1", "name": "Arginase", "aln": "----------------METGPHYNYYKNRE-LSIVLAPFSGGQGKLGVEKGPKYMLKHGLQTSIEDLGWSTELEPSMDEAQFVGKLKMEKDSTTGGSSVMIDGVKAKRADLVGEATKLVYNSVSKVVQANRFPLTLGGDHSIAIGTVSAVLDKYPDAGLLWIDAHADINTIESTPSGNLHGCPVSFLMG-LNKDVPHCPESLKWVPGNLSPKKIAYIGLRDVDAGEKKILKDLGIAAFSMYHVDKYGINAVIEMAMKAVHPETNGEGPIMCSYDVDGVDPLYIPATGTPVRGGLTLREGLFLVERLAESGNLIALDVVECNPDLAIHDIHVSNTISAGCAIARCALGETLL--------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "O76895-1", "uniprot_id": "O76895_DROME", "id": "O76895-1", "name": "Arginase", "aln": "MWWSRKFASRSLRLHRLKSTGSTAPREPEQSLGIIGVPFAKGQAKQGVELAPDLLRQSSLRQVLQSSHDGLVIR-DYGNLQYAVDEPLLQQQRVHYHHIRNY-------ADFMACNRALIEQVKLMLVENTQFLAIGGDHAIGFGSVAGHLQHTPNLSLVWIDAHADINLHSTSQSGNIHGMPVSFLLEQLRNTWQHAGL-QEIAPNCLPKDQLVYIGLRDIDPYEAFILNKVGIRYYAMDTIDRVGVPKIIEMTLDALNPQN----KIHVSFDIDALDSNVAPSTGTAVRGGLTLREGISIVEALRDTKRVQGVDLVEINPKLGS-ERDVRTTVESGLEILKSMFGYRRSGRWSNIDTGILGSD------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. . . :.:: .**: ** : *** .* : : .* :. . .: .:. : ::. : . ..: : : *. : . :::****::.:*:: . : *: ::*:******* :: ***:** *:***: *.. : . :. .:.******::. * **:. .* ::* :*: *: ::* ::. : : * *:*:*..*. *:***.* **** ***: :.* : .: : .:*:** **.*. : .. * . : . :* ", "identical_positions": 74, "similar_positions": 110, "identity": "19.63%" }, { "cls_id": "homologset.agr.MGI:1330808", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62904-1", "uniprot_id": "DHB7_RAT", "id": "Q62904-1", "name": "3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7", "aln": "-MRKVVLITGASSGIGLALCGRLLAEDDD---LHLCLACRNLSKAGAVRDALLASHP--------SAEVSIVQMDVSNLQSVVRGAEEVKRRFQRLDYLYLNAGIMPNPQLNLKAFFCGIFSRNVIHMFSTAEGLLTQNDKITADGFQEVFETNLFGHFILIRELEPLLCHSDNPSQLIWTSSRNAKKSNFSLEDIQHAKGQEPYSSSKYATDLLNVALNRNFNQKGLYSSVTCPGVVMTNLTYGILPPFVWTLLLPVIWLLRFFAHAFT-VTPYNGAEALVWLFHQK-PESLNPLTKYLSGTTGLGTNYVKGQKMDVD--EDTAEKFYKTLLELEKQVRITIQKSDHHS-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88736-1", "uniprot_id": "DHB7_MOUSE", "id": "O88736-1", "name": "3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7", "aln": "-MRKVVLITGASSGIGLALCGRLLAEDDD---LHLCLACRNLSKARAVRDTLLASHP--------SAEVSIVQMDVSSLQSVVRGAEEVKQKFQRLDYLYLNAGILPNPQFNLKAFFCGIFSRNVIHMFTTAEGILTQNDSVTADGLQEVFETNLFGHFILIRELEPLLCHADNPSQLIWTSSRNAKKANFSLEDIQHSKGPEPYSSSKYATDLLNVALNRNFNQKGLYSSVMCPGVVMTNMTYGILPPFIWTLLLPIMWLLRFFVNALT-VTPYNGAEALVWLFHQK-PESLNPLTKYASATSGFGTNYVTGQKMDID--EDTAEKFYEVLLELEKRVRTTVQKSDHPS-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P56937-1", "uniprot_id": "DHB7_HUMAN", "id": "P56937-1", "name": "3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7", "aln": "-MRKVVLITGASSGIGLALCKRLLAEDDE---LHLCLACRNMSKAEAVCAALLASHP--------TAEVTIVQVDVSNLQSVFRASKELKQRFQRLDCIYLNAGIMPNPQLNIKALFFGLFSRKVIHMFSTAEGLLTQGDKITADGLQEVFETNVFGHFILIRELEPLLCHSDNPSQLIWTSSRSARKSNFSLEDFQHSKGKEPYSSSKYATDLLSVALNRNFNQQGLYSNVACPGTALTNLTYGILPPFIWTLLMPAILLLRFFANAFT-LTPYNGTEALVWLFHQK-PESLNPLIKYLSATTGFGRNYIMTQKMDLD--EDTAEKFYQKLLELEKHIRVTIQKTDNQARLSGSCL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q12452-1", "uniprot_id": "ERG27_YEAST", "id": "Q12452-1", "name": "3-keto-steroid reductase ERG27", "aln": "MNRKVAIVTGTNSNLGLNIVFRLIETEDTNVRLTIVVTSRTLPRVQEVINQIKDFYNKSGRVEDLEIDFDYLLVDFTNMVSVLNAYYDINKKYRAINYLFVNAAQGIFDGIDWIGAVKEVFT-NPLEAVTNPTYKIQLVGVKSKDDMGLIFQANVFGPYYFISKILPQLTRG--KAYIVWISSIMSDPKYLSLNDIELLKTNASYEGSKRLVDLLHLATYKDLKKLGINQYVVQPGIFTSHSFSEYLNFFTYFGMLCLFYLARLLGSPWHNIDGYKAANAPVYVTRLANPNFEKQDVKYGSATSRDGMPYIKTQEIDPTGMSDVFAYIQKKKLEWDEKLKDQIVETRTPI-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ***.::**:.*.:** : **: :* * : ::.*.:.:. * : : :. : :*.:.: **... ::::::: :: :::**. :: . . :*: : :. .:.. : . : *.: :*::*:** : :* :: * * :. : ::* ** : :**:*:: * .*..** .*** :* ::::: *: . * ** :: * * : :: : * *:: . : *:.::* *:: : *: : ** *.*: * *: *::* .*. : : ** ::::: : :: ", "identical_positions": 65, "similar_positions": 129, "identity": "18.21%" }, { "cls_id": "homologset.agr.MGI:1330809", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O54827-1", "uniprot_id": "AT10A_MOUSE", "id": "O54827-1", "name": "Phospholipid-transporting ATPase VA", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------MERELPA-AEESASSGWRRPRRRRW--EGRTRTVRSNLLPPLGTEDSTIGAPKGERLLMRGCI---------------QHLADNRLKTTKYTLLSFLPKNLFEQFHRLANVYFVFIALLNFVPAVNAFQPGLALAPVLFILAVTAIKDLWEDYSRHRSDHEINHLGCLVFSREEK-----------------------------------------------------------------------------------------------------------------KYVNRYWKEIRVGDFVRLCCNEIIPADILLLSSSDPDGLCHIETANLDGETNLKRRQVVRGFSELVSEFNPLTFTSVIECEKPNNDLSRFRG-----YIMHSNGEKAGLHKENLLLRGCTIRNTEAVAGIVIYAGHETKALLNNSGPRYKRSQLERQMNCDVLWCVLLLVCISLFSAVGHGLWVRRYQEKKALFDVPESDGSSLSPATAAVYSFFTMIIVLQVLIPISLYVSIEIVKVCQVYFINQDIELYDEETDSQLQCRALNITEDLGQIKYIFSDKTGTLTENKMVFRRCTVSGIEYSHDANAQRLARYQEADSEEEEVVSKVGTISHRGSTGSHQSIWMTHKTQSIKSHRRTGSRAEAKRASMLSKHTAFSSPMEKDITPDPKLLEKVSECDRFLAIAR-HQEHPLAHLSPELSDVFDFFIALTICNTVVVTSPDQPRQKVRVRFELKSPVKTIEDFLRRFTPSRLASG--CSSIGNLSTSKSS-HKSGSAFLPSLSQDSMLLGLEEKLGQTAPSIASNGYASQAGQEESWASECTTDQKCPGEQREQQEGELRYEAESPDEAALVYAARAYNCALVDRLHDQVSVELPHLGR-LTFELLHTLGFDSIRKRMSVVIRHPLTDEINVYTKGADSVVMDLLLPCSSDDARGRHQKKIRSKTQNYLNLYAVEGLRTLCIAKRVLSKEEYACWLQSHIEAEASVESREELLFQSAVRLETNLHLLGATGIEDRLQEGVPETIAKLRQAGLQIWVLTGDKQETAINIAYACKLLDHGEEVITLNADSQEACAALLDQCLSYVQSR---NPRSTLQNSESNLSVGFS--FNPVSTSTDAS----PSPSLVIDGRSLAYALEKS--LEDKFLFLAKQCRSVLCCRSTPLQKSMVVKLVRSKLKAMTLAIGDGANDVSMIQVADVGVGISGQEGMQAVMASDFAVPRFRYLERLLIVHGHWCYSRLANMVLYFFYKNTMFVGLLFWFQFYCGFSASAMIDQWYLIFFNLLFSSLPQLVTGVLDKDVPADMLLREPQLYKSGQNMEEYRPRAFWLNMVDAAFQSLVCFFIPYLAYYDSDVDVFT---------WGTPVTAIALFTFLLHLGIETKTWTWLNWLACGFSTFLFFSVALIYNTSCATCYPPSNPYWTMQTLLGDPLFYLTCLIAPIAALLPRLFFKALQGSLFPTQLQLGRQLAKK-----------------PLNKFSDPKETFAQGQPPGHSETELSERKTMGPFETLPRDCASQASQFTQQLTCSPEASGEPSAVDTNMPLRENTLLEGLGSQASGSSMPRGAIS---EVCPGDSKR---QSTSASQTARLSSLFHLPSFGSLNWISSLSLASGLGSVLQLSGSSLQMDKQDGEFLSNPPQPEQDLHSFQGQVTGYL----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2JWQ8-1", "uniprot_id": "A0A0G2JWQ8_RAT", "id": "A0A0G2JWQ8-1", "name": "Phospholipid-transporting ATPase", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------MERESAA-AEEPASPGRRRPRRRRW--EGRTRTVRSNLLPSLGTEDSTAGASKGERLLMRGCI---------------QHLADNRLKTTKYTLLSFLPKNLFEQFHRLANVYFVFIALLNFVPAVNAFQPVLALAPVLFILAVTAIKDLWEDYSRHRSDHEINHLGCLVFSREEK-----------------------------------------------------------------------------------------------------------------KYVNRYWKEIRVGDFVRLCCNEIIPADILLLSSSDPDGLCHIETANLDGETNLKRRQVVRGFSELVSEFNPLTFTSVIECEKPNNDLSRFRG-----CIIHSNGEKAGLHKENLLLRGCTIRNTEAVAGIVIYAGHETKALLNNSGPRYKRSQLERQMNCDVLWCVLLLVCISLFSAVGHGLWVRRYQEKKALFDVPESDGSSLSPATAAVYSFLTMIIVLQVLIPISLYVSIEIVKVCQVYFINQDIELYDEETDSQLQCRALNITEDLGQIKYIFSDKTGTLTENKMVFRRCTVSGIEYSHDANAQRLAKYQEADSEEEEMVSKVGPISHRGSTGSHQSIWMTHKTQSIKSHRRTGSRAEAKRASMLSKHTAFSSPMEKDITPDPKLLEKVSECDRFLSIAR-HQEHPLAHLSPELSDVFDFFIALTICNTVVVTSPDQPRQKVRVRFELKSPVKTIEDFLRKFTPSRLASG--CSSIGNLTNNKSS-NKSGSTFLPSLSQDNMLLRLEERLGQTAPVIASNGYASQASQAESWTSECTSEQKCPGDQREQQEGELRYEAESPDEAALVYAAKAYNCALVDRLHDQVSVELPHLGR-LTFELLHTLGFDSIRKRMSVVIRHPLTDEINVYTKGADSVVMDLLLPCSSDDARGRHQKKIRSKTQNYLNLYAVEGLRTLCIAKRVLSKEEYACWLQSHIEAETSVESREELLFQSAVRLETNLHLLGATGIEDRLQDGVPETIAKLRQAGLQIWVLTGDKQETAINIAYACKLLDHGEEVITLNADSREACAALLDQCLCYVQSR---NSRSVPQNSESSFSVGFS--FNPASTSTDSS----PSPSLVIDGRSLAYALEKS--LEDKFLFLAKQCRSVLCCRSTPLQKSMVVKLVRNKLKAMTLAIGDGANDVSMIQVADVGVGISGQEGMQAVMASDFAVPRFRYLERLLIVHGHWCYSRLANMVLYFFYKNTMFVGLLFWFQFYCGFSASAMIDQWYLIFFNLLFSSLPQLVTGVLDKDVPADMLLRKPQLYKSGQNMEEYSPRAFWLNMVDAAFQSLVCFFIPYLAYYDSDVDVFT---------WGTPVTAIALFTFLLHLGIETKTWTWLNWLACGFSTFLFFSVALIYNTSCATCYPPSNPYWTMPTLLGDPLFYLTCLIAPVAALLPRLFFKALQGSLFPTQLQLGRQLAKK-----------------SLNKFSVPKETFAQGQPPGHTEPELSERKAMGPFESLPRDCASQASQFTQQLACSPEASGEPSAVDTNMPLRENTLLEGLGSQASGSAMPREAIS---EDCPGDSKR---KSTSASQTAPLSSLFHLPSFGSLNWISSLSLASGLGSVLQLSRSSLQMDKQDGEFLSNPPQPDQDLHNLQGQVTGYF----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O60312-1", "uniprot_id": "AT10A_HUMAN", "id": "O60312-1", "name": "Phospholipid-transporting ATPase VA", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEREPAG-TEEPGPPG----RRRRR--EGRTRTVRSNLLPPPGAEDPAAGAAKGERRRRRGCA---------------QHLADNRLKTTKYTLLSFLPKNLFEQFHRPANVYFVFIALLNFVPAVNAFQPGLALAPVLFILAITAFRDLWEDYSRHRSDHKINHLGCLVFSREEK-----------------------------------------------------------------------------------------------------------------KYVNRFWKEIHVGDFVRLRCNEIFPADILLLSSSDPDGLCHIETANLDGETNLKRRQVVRGFSELVSEFNPLTFTSVIECEKPNNDLSRFRG-----CIIHDNGKKAGLYKENLLLRGCTLRNTDAVVGIVIYAGHETKALLNNSGPRYKRSKLERQMNCDVLWCVLLLVCMSLFSAVGHGLWIWRYQEKKSLFYVPKSDGSSLSPVTAAVYSFLTMIIVLQVLIPISLYVSIEIVKACQVYFINQDMQLYDEETDSQLQCRALNITEDLGQIQYIFSDKTGTLTENKMVFRRCTVSGVEYSHDANAQRLARYQEADSEEEEVVPRGGSVSQRGSIGSHQSVRVVHRTQSTKSHRRTGSRAEAKRASMLSKHTAFSSPMEKDITPDPKLLEKVSECDKSLAVAR-HQEHLLAHLSPELSDVFDFFIALTICNTVVVTSPDQPRTKVRVRFELKSPVKTIEDFLRRFTPSCLTSG--CSSIGSLAANKSS-HKLGSSFPSTPSSDGMLLRLEERLGQPTSAIASNGYSSQADN---WASELAQEQ--------ESERELRYEAESPDEAALVYAARAYNCVLVERLHDQVSVELPHLGR-LTFELLHTLGFDSVRKRMSVVIRHPLTDEINVYTKGADSVVMDLLQPCSSVDARGRHQKKIRSKTQNYLNVYAAEGLRTLCIAKRVLSKEEYACWLQSHLEAESSLENSEELLFQSAIRLETNLHLLGATGIEDRLQDGVPETISKLRQAGLQIWVLTGDKQETAVNIAYACKLLDHDEEVITLNATSQEACAALLDQCLCYVQSR---GLQRAPEKTKGKVSMRFSS-LCPPSTSTASG----RRPSLVIDGRSLAYALEKN--LEDKFLFLAKQCRSVLCCRSTPLQKSMVVKLVRSKLKAMTLAIGDGANDVSMIQVADVGVGISGQEGMQAVMASDFAVPKFRYLERLLILHGHWCYSRLANMVLYFFYKNTMFVGLLFWFQFFCGFSASTMIDQWYLIFFNLLFSSLPPLVTGVLDRDVPANVLLTNPQLYKSGQNMEEYRPRTFWFNMADAAFQSLVCFSIPYLAYYDSNVDLFT---------WGTPIVTIALLTFLLHLGIETKTWTWLNWITCGFSVLLFFTVALIYNASCATCYPPSNPYWTMQALLGDPVFYLTCLMTPVAALLPRLFFRSLQGRVFPTQLQLARQLTRK-----------------SPRRCSAPKETFAQGRLPKDSGTEHSSGRTVK--TSVP---LSQPSWHTQQPVCSLEASGEPSTVDMSMPVREHTLLEGLSAPAPMSSAPGEAVLRSPGGCPEESKV---RAASTGRVTPLSSLFSLPTFSLLNWISSWSLVSRLGSVLQFSRTEQLADGQAG--RGLPVQPHSGRSGLQGPDHRLLIGASSRRSQ-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7T882-1", "uniprot_id": "A0A8N7T882_DANRE", "id": "A0A8N7T882-1", "name": "Phospholipid-transporting ATPase", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------MARETGE-SGETKSGKVKKHKRRKSKKESKTRTVHANILY-----DHTKGGDNPNR-----------------------HYANNKIKTTKYTLLSFLPKNLFEQFHRFANVYFVFIALLNFVPVVNAFQPELALAPVVFILSVTAIKDLWEDYRRHRSDKEINHMDCLVYCRSEK-----------------------------------------------------------------------------------------------------------------RYVEKYWKELRVGDFIRLRCNEILPADVLLLSTSDPDRLCHIETATLDGETNLKQRQVVRSFIDLDCEFDPLKYNSVIECEKPNNDLNRFRG-----YIIHRSGRRDGLYKDNLLLRGCTIRNTEEAVGIVIYAGHETKAMLNNNGPRYKRSKLERQMNVDVFWCVIILLVMCLFSAIGHGLWMFQYGDKRPVFDVLGPEGTELSPVVSAIYLFLTMIIVFQVLIPISLFVSIEIVKICQVYFIHQDLELYDEETDSHLQCRALNITEDLGQMQYIFSDKTGTLTENKMVFRRCTVAGVEYSHDANARRIAMYQEVESEEEDCTSHGGTLPRRDSVASHQSGKVVLRSQSTKSHRRTGSRAEAKRASILSKHTAFSSPMEKDITPDPQLMDKVNECSSQMEFMR-FHSQSLNQIPPDLCDVFDFFIALTICNTVVVSSPNQPRQKVR-RFELKSPVKTIEDFIKRFTPSRLTSGSNSSSSSSLATNRSSSHKLGCSMLSSPSAENTLTKLNEEKRQ--EHDLQHAFSPVPPN---FDKSKALAQ---------DECELRFEAESPDEAALVYAARAYKCALVGRLPDQVTVELPHLGK-LSFELLHTLGFDSTRKRMSVVVKHPLTEQITVYTKGADSVIMDLIRPAT-DDCKGKRQRKILYKTQNYLNLYAADGLRTLCIAKKVLSKEEYASWLQRHLEAETAIQRREELLFESALRLETNLQLLGATGIEDRLQDGVPETIASLRKAGLQIWVLTGDKQETAINIAYACKLLDPEEEIITLNADSQEACARLLENSLHYIQAKFLCDPRAGPQAAGDYAGIHFSSPVCSPTSSGHSGPFLVHRLGLVIDGRTLAYALDKS--LEDKFLAVARSCRSVLCCRSTPLQKSMVVKLVRNKLKVMTLAIGDGANDVSMIQVADVGVGISGQEGMQAVMASDFALPRFRYLQKLLLVHGHWCYSRLANMILYFFYKNAMFVALIFWYQFYCGFSGSAMVDQWYLIFFNLMFSAFPQLITGTLDKDVSAETLQELPQLYMNGQNSEEYKPYMFWMNMIDAFYQSLICFFIPYFAYIDSDVDLFT---------WGTPITTLALFTILLHLGIETKTWTWMNWVSIGFSMALFFTVALCYNASCPTCFSPSNTYWTMQRLLGDPLFYLLCVVTPVAALLPRYCYRACQGTLFPNPVHMGRQLDKLPVEMRRLVLSQSQMKLGSLGSLFAPRAPFFPLCRPFQKDYRPKAKQSHVSSTKPKEKSLASPISSKSVEMRDTPVSSKNSDNHIKLNFRKQDKAQSCR-QASDGPVPENLCYVKEPSSPITGTLPYTKDTPASRTLLESTGLEVPLSPTGLLLSSTPLLSQTETMQLTSPPASCFLGQKLNDEELSNQ-KSLLKQSQDRDHSCLPEHSLKTTFL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7KTG6-1", "uniprot_id": "Q7KTG6_DROME", "id": "Q7KTG6-1", "name": "Phospholipid-transporting ATPase", "aln": "MPSANTEDLRRKFLVVQQQRSAPPNLTGDTLSSGIPNASASSATTSLMMTTSTGLGGVAMGAGEPERTYVFPGGNPVVGSAPGGGGQGIPGVAMAAPSRGHARSISHGGGAIVGANGRPIKSAMKGHQRAFSQGQITDSPPGSAAPAGRGHSRVGSKTDFILPPGHKEEPAREPSAPTSATGGRGHSRQASRSESIYTLRRTEAPPWWKRLTLCNYNTGDKFEERSYRTVVPNHTVPPKTPKRDHPNGQFVGNKIRTTKYTLLSFIPKNLLEQFHRVANLYFIFIVLLNWVPEISAFGKEVAMIPVLFVLGVTAVKDLFEDRRRRASDKRINNTTCRVYDGETE-----------------------------------------------------------------------------------------------------------------RYKKVKWQELRVGDIVHLSNNETVPADILLLRTSDPQGVCYIDTCDLDGETNLKRREVVRGFEEMQSIFVPSKFVSRVEADAPTTKLYRFHG-----ALIHPTGERVPISTECLLLRESRLKNTDYIEGIVVYAGHETKSMLNNSGPRYKRSQVEQQMNIDVIWCVIILLILCVVGAIGCRMWLSSFTH----FPVPYLPPNKLTANMESMWIFWTYIVILQVMIPLSLYVTIELCKILQVFHIHNNVDLFDAETNKQTECRAMNITEELGQIQHIFTDKTGTLTENKMIFRRCVVNGSDYNHPP------------SELEKIYSKPGAPAPPLIPNDNLNSDMAQLTQGTYLTPHAQRIQEFLVVLAICNTVIVGAAPHRDMMNASGIIEVQQIGNSPANLKHGKQRQKLLASSTSTTTTTTIINGPTTQPQVVSIPADRYIRLAESRSVTPSPPPNLLFALPAQSHQPTLSP-ISSSAESSPNSESESPSPPMKNKSLSNSISPTGRAKAVINSKITSIATFLNAKTQGKRMKLPSSKTGTIYR------TADGRPLYEAESPDELALVNAAYSYDCCLLNRSPNQILVSMPMAGATREYEILKVLPFDSSRKCMSIVVRQIGSQEIVLYTKGADSSIMPVLVPCSHNSPEG----ILREQTQQLLDRYAREGLRILVMAKRTLNSADYTDWWARHQEIEMSLENRERRLRDSFAKLESNLTLLGATGIEDRLQDGVPETIASLLSAGISVWVLTGDKPETAINIAYSAKLFTQQMELIRLTARSRDAAETAINFYLTDMEND------------KTTSTLGYG-------QSLRKK-----QRALVVDGKTLTFILDPKSKLILPFLRLSKRCASVLCCRSTPLQKAYLVKVVKEELNLRTLAIGDGANDVSMIQMADVGVGISGQEGMQAVMAADFTLPRFRYLERLLLAHGYWCYDRLSRMILYFFYKNAAFVFLIFWYQLYCGFSGQVMMDQMYLMLYNLIFTSLPPLAIGVYDKRVAEDLLLKNPYLYKNGRLGVAYRPHDFWLILLDALYQSLVIFFVALCAYAESDVGIWE---------FGTTITASCLFANLVHCAIEIRSWTVLHVLSIVLSLGSFYLFAIVYDSVCMNCFGVRSSYWVIFVCFASAVHWLVIMLSTVVAVLPRLLLTTVRISLCP-----------------------------------------------------------------------------------------DDSTKVILQSKRERSRGEALL-------------------------------VTWSRSTSASSIYRITDYGSKNQIITTIT--------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12675-1", "uniprot_id": "ATC4_YEAST", "id": "Q12675-1", "name": "Phospholipid-transporting ATPase DNF2", "aln": "-------------------MSSPSKPTSPFVDDIEHESGSASNGLSSMSPFDDSFQFEKPSSAHGNIEVAKTGGSVLKRQSKPMKDISTPDLSKVTFDGIDDYSNDNDINDDDELNGKKTEIHEHENEVDDDLHSFQATPMPNTGG--FEDVELDNNEGSNNDSQADHKLKRVRFGTRRNKSGRIDINRSKTLKWAKKNFHNAIDEFSTKEDSLENSALQNRSDELRTVYYNLPLPEDMLDEDGLPLAVYPRNKIRTTKYTPLTFFPKNILFQFHNFANIYFLILLILGAFQIFGVTNPGFASVPLIVIVIITAIKDGIEDSRRTVLDLEVNNTRTHILSGVKNENVAVDNVSLWRRFKKANTRALIKIFEYFSENLTAAGREKKLQKKREELRRKRNSRSFGPRGSLDSIGSYRMSADFGRPSLDYENLNQTMSQANRYNDGENLVDRTLQPNPECRFAKDYWKNVKVGDIVRVHNNDEIPADMILLSTSDVDGACYVETKNLDGETNLKVRQSLKCSKIIKSSRDITRTKFWVESEGPHANLYSYQGNFKWQDTQNGNIRNEPVNINNLLLRGCTLRNTKWAMGMVIFTGDDTKIMINAGVTPTKKSRISRELNFSVILNFVLLFILCFTAGIVNGVYYKQKPRSRDYFEFGTIGG---SASTNGFVSFWVAVILYQSLVPISLYISVEIIKTAQAIFIYTDVLLYNAKLDYPCTPKSWNISDDLGQIEYIFSDKTGTLTQNVMEFKKCTINGVSY--------------------------GRAYTEALAGLRKRQGVDVESEGRREKEEIAKDRETMIDELRSMSDNTQFCPEDLTFVSKEIVEDLKGSSG----------------DHQQKCCEHFLLALALCHSVLVEPNKD----------------------------------------------------------------------------------------------------------------DPKKLDIKAQSPDESALVSTARQLGYSFVGSSKSGLIVEIQGVQK--EFQVLNVLEFNSSRKRMSCIIKIPGSTPKDEPKALLICKGADSVIYSRLDR--TQNDATLLEKTALHLEEYATEGLRTLCLAQRELTWSEYERWVKTYDVAAASVTNREEELDKVTDVIERELILLGGTAIEDRLQDGVPDSIALLAEAGIKLWVLTGDKVETAINIGFSCNVLNNDMELLVVKASGEDVEEFGSDPIQVVNNLVT----------KYLREKFGMSGSEEELKEAKREHGLPQGNFAVIIDGDALKVALNGE-EMRRKFLLLCKNCKAVLCCRVSPAQKAAVVKLVKKTLDVMTLAIGDGSNDVAMIQSADVGVGIAGEEGRQAVMCSDYAIGQFRYVTRLVLVHGKWCYKRLAEMIPQFFYKNVIFTLSLFWYGIYNNFDGSYLFEYTYLTFYNLAFTSVPVILLAVLDQDVSDTVSMLVPQLYRVGILRKEWNQTKFLWYMLDGVYQSVICFFFPYLAYHKNMVVTENGLGLDHRYFVGVFVTAIAVTSCNFYVFMEQYRWDWFCGLFICLSLAVFYGWTGIWTSSSS----SNEFYKGAARVFAQPAYWAVLFVGVLFCLLPRFTIDCIRKIFYPKDIEIVREMWLRG---------------------------DFDLYPQGYDPTDPSRPRINEIRPLTD-FKEPISLDTHFDGVSHSQETIVTEEIPMSILNGEQGSRKGYRVSTTLER--RDQLSPVTTTNNLPRRSMASARGNKLRTSLDRTREEMLANHQLDTRYSVERARASLDLPGINHAETLLSQRSRDR--------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P32660-1", "uniprot_id": "ATC5_YEAST", "id": "P32660-1", "name": "Phospholipid-transporting ATPase DNF1", "aln": "-------------------MSG----------------TFHGDGHAPMSPFEDTFQFEDNSSNE-DTHIAPT----------HFDDGATSNKYSRPQVSFNDETPKNKREDAEEFT--------FNDDTEYDNHSFQPTPKLNNGSGTFDDVELDNDSGEPHTN--YDGMKRFRMGTKRNKKGNPIMGRSKTLKWARKNIPNPFEDFTK--DDIDPGAIN-RAQELRTVYYNMPLPKDMIDEEGNPIMQYPRNKIRTTKYTPLTFLPKNILFQFHNFANVYFLVLIILGAFQIFGVTNPGLSAVPLVVIVIITAIKDAIEDSRRTVLDLEVNNTKTHILEGVENENVSTDNISLWRRFKKANSRLLFKFIQYCKEHLTEEGKKKRMQRKRHELRVQKTVGTSGPRSSLDSIDSYRVSADYGRPSLDYDNLEQGAGEAN-------IVDRSLPPRTDCKFAKNYWKGVKVGDIVRIHNNDEIPADIILLSTSDTDGACYVETKNLDGETNLKVRQSLKCTNTIRTSKDIARTKFWIESEGPHSNLYTYQGNMKWRNLADGEIRNEPITINNVLLRGCTLRNTKWAMGVVMFTGGDTKIMLNSGITPTKKSRISRELNFSVVINFVLLFILCFVSGIANGVYYDKKGRSRFSYEFGTIAG---SAATNGFVSFWVAVILYQSLVPISLYISVEIIKTAQAAFIYGDVLLYNAKLDYPCTPKSWNISDDLGQVEYIFSDKTGTLTQNVMEFKKCTINGVSY--------------------------GRAYTEALAGLRKRQGIDVETEGRREKAEIAKDRDTMIDELRALSGNSQFYPEEVTFVSKEFVRDLKGASG----------------EVQQRCCEHFMLALALCHSVLVEANPD----------------------------------------------------------------------------------------------------------------NPKKLDLKAQSPDEAALVATARDVGFSFVGKTKKGLIIEMQGIQK--EFEILNILEFNSSRKRMSCIVKIPGLNPGDEPRALLICKGADSIIYSRLSRQSGSNSEAILEKTALHLEQYATEGLRTLCIAQRELSWSEYEKWNEKYDIAAASLANREDELEVVADSIERELILLGGTAIEDRLQDGVPDCIELLAEAGIKLWVLTGDKVETAINIGFSCNLLNNEMELLVIKTTGDDVKEFGSEPSEIVDALLS----------KYLKEYFNLTGSEEEIFEAKKDHEFPKGNYAIVIDGDALKLALYGE-DIRRKFLLLCKNCRAVLCCRVSPSQKAAVVKLVKDSLDVMTLAIGDGSNDVAMIQSADVGIGIAGEEGRQAVMCSDYAIGQFRYLARLVLVHGRWSYKRLAEMIPEFFYKNMIFALALFWYGIYNDFDGSYLYEYTYMMFYNLAFTSLPVIFLGILDQDVNDTISLVVPQLYRVGILRKEWNQRKFLWYMLDGLYQSIICFFFPYLVYHKNMIVTSNGLGLDHRYFVGVYVTTIAVISCNTYVLLHQYRWDWFSGLFIALSCLVVFAWTGIWSSAIA----SREFFKAAARIYGAPSFWAVFFVAVLFCLLPRFTYDSFQKFFYPTDVEIVREMWQHG---------------------------HFDHYPPGYDPTDPNRPKVTKAGQHGEKIIEGIALSDNLGGSNYSRDSVVTEEIPMTFMHGEDGSPSGYQKQETWMTSPKETQDLLQSPQFQQAQTFGRGPSTNVRSSLDRTREQMIATNQLDNRYSVERARTSLDLPGVTNAASLIGTQQNN---------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . : :. *:::***** *:*:***:: ***. **:**:.: :*. . ... .: *::.:: :**.:* ** * * .:*: : : :: : *: ::***:::: *: .***::** :** : *:::* ******** *: :: : :*.: * .* ::* . .. : : :*** . ::**. *:*:::* :** ::* . . *:*::.:::* .*. .::*. :.. ..: :: : . :. .. * . ::: * ::*:**::::*: * *. .* :: *:: : : :: **:::***:::**:*******:* * *::*.: * .* * . : ::. . : . . :: . . . :: . : *: . . :*:**** *** :* :: . : :.: :::*: * *:* ** ** ::: . : . : :* *: ** :*** * :*:: *. :* * : :: * * :* :* ***.*.******:***: * * .**:.:******* ***:**.::.::: *:: :.: . :. : . : .:::** :* * . : ** :.: * :***** :* **: :**:*:. *. *******:***:*** ****:**:*:** ****.:*::: :***: :*:: ** *.*.**:.*: ***** *. :**: :: .*... : : *: ::** *::.* : . *: * * ** * : * : *. :**:: * .. .* .. : *. :.: .: : : :. * : : :* .: : : : . : . . .: .: : .:*** : . * . : .. : : : : ", "identical_positions": 257, "similar_positions": 339, "identity": "13.74%" }, { "cls_id": "homologset.agr.MGI:1330810", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JJP6-1", "uniprot_id": "P63_RAT", "id": "Q9JJP6-1", "name": "Tumor protein 63", "aln": "MNFETSRCATLQYCPDPYIQRFIETP-SHFSWKESYYRSAMSQS--TQTSEFLSPEVFQHIWDFLEQ----PICSVQPIDLNFVDEPSENGATNKIEISMDCIRMQDSDLSDPMWPQYTNLGLLNGMDQQIQNGSSSTSPYNTDHAQNSVTAP-------------SPYAQPSSTFDALSPSPAIPSN------TDYPGPHSFDVSFQQSSTAKSATWTYSTELKKLYCQIAKTCPIQIKVMTPPPQGAVIRAMPVYKKAEHVTEVVKRCPNHELSREFNEGQIAPPSHLIRVEGNSHAQYVEDP----ITGRQSVLVPYEPP----QVGTEFTTVLYNFMCNSSCVGGMNRRPILIIVTLETRDGQVLGRRCFEARICACPGRDRKADEDSIRKQQVSDSAKNGDGTKRPFRQN-THGIQMTSIKKRRSPDDELLYLPVRGRETYEMLLKIKESLELMQYLPQHTIETYRQQQQQQHQHLLQKQTSMQSQSSYGNSSPPLNKMNSMNKLPSVSQLINPQQRNALTPTTMPEGMG-------------ANIPMMGTHMPMAGDMNGLSPTQALPPPLSMPSTSHCTPPPPYPTDCSIVSFLARLGCSSCLDYFTTQGLTTIYQIEHYSMDDLASLKIPEQFRHAIWKGILDHRQLHDFSSPPHLLRTPSGASTVSVGSSETRGERVIDAVRFTLRQTISFPPRDEWNDFNFDMD--SRRNKQQRIKEEGE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88898-1", "uniprot_id": "P63_MOUSE", "id": "O88898-1", "name": "Tumor protein 63", "aln": "MNFETSRCATLQYCPDPYIQRFIETP-AHFSWKESYYRSAMSQS--TQTSEFLSPEVFQHIWDFLEQ----PICSVQPIELNFVDEPSENGATNKIEISMDCIRMQDSDLSDPMWPQYTNLGLLNSMDQQIQNGSSSTSPYNTDHAQNSVTAP-------------SPYAQPSSTFDALSPSPAIPSN------TDYPGPHSFDVSFQQSSTAKSATWTYSTELKKLYCQIAKTCPIQIKVMTPPPQGAVIRAMPVYKKAEHVTEVVKRCPNHELSREFNEGQIAPPSHLIRVEGNSHAQYVEDP----ITGRQSVLVPYEPP----QVGTEFTTVLYNFMCNSSCVGGMNRRPILIIVTLETRDGQVLGRRCFEARICACPGRDRKADEDSIRKQQVSDSAKNGDGTKRPFRQN-THGIQMTSIKKRRSPDDELLYLPVRGRETYEMLLKIKESLELMQYLPQHTIETYRQQQQQQHQHLLQKQTSMQSQSSYGNSSPPLNKMNSMNKLPSVSQLINPQQRNALTPTTMPEGMG-------------ANIPMMGTHMPMAGDMNGLSPTQALPPPLSMPSTSHCTPPPPYPTDCSIVSFLARLGCSSCLDYFTTQGLTTIYQIEHYSMDDLASLKIPEQFRHAIWKGILDHRQLHDFSSPPHLLRTPSGASTVSVGSSETRGERVIDAVRFTLRQTISFPPRDEWNDFNFDMD--SRRNKQQRIKEEGE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H3D4-1", "uniprot_id": "P63_HUMAN", "id": "Q9H3D4-1", "name": "Tumor protein 63", "aln": "MNFETSRCATLQYCPDPYIQRFVETP-AHFSWKESYYRSTMSQS--TQTNEFLSPEVFQHIWDFLEQ----PICSVQPIDLNFVDEPSEDGATNKIEISMDCIRMQDSDLSDPMWPQYTNLGLLNSMDQQIQNGSSSTSPYNTDHAQNSVTAP-------------SPYAQPSSTFDALSPSPAIPSN------TDYPGPHSFDVSFQQSSTAKSATWTYSTELKKLYCQIAKTCPIQIKVMTPPPQGAVIRAMPVYKKAEHVTEVVKRCPNHELSREFNEGQIAPPSHLIRVEGNSHAQYVEDP----ITGRQSVLVPYEPP----QVGTEFTTVLYNFMCNSSCVGGMNRRPILIIVTLETRDGQVLGRRCFEARICACPGRDRKADEDSIRKQQVSDSTKNGDGTKRPFRQN-THGIQMTSIKKRRSPDDELLYLPVRGRETYEMLLKIKESLELMQYLPQHTIETYRQQQQQQHQHLLQKQTSIQSPSSYGNSSPPLNKMNSMNKLPSVSQLINPQQRNALTPTTIPDGMG-------------ANIPMMGTHMPMAGDMNGLSPTQALPPPLSMPSTSHCTPPPPYPTDCSIVSFLARLGCSSCLDYFTTQGLTTIYQIEHYSMDDLASLKIPEQFRHAIWKGILDHRQLHEFSSPSHLLRTPSSASTVSVGSSETRGERVIDAVRFTLRQTISFPPRDEWNDFNFDMD--ARRNKQQRIKEEGE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58JQ56-1", "uniprot_id": "A0AC58JQ56_DANRE", "id": "A0AC58JQ56-1", "name": "Tumor protein 63 (p63)", "aln": "---MTSPYAAVQFCPERAFQRLREPAAACLSWAEGSFLASMSQGQGSQGTDILGQDVLNQLLEMLDQS---ALHSMQPIELNFSEGSSVGSASNTIQISMDCITMHGP--EEPLTPQYTSLGLLNSMDQ--NGGSTSTSPYNNDHAQNNVTAP-------------SPYAQPSSTFEALSPSPAIPSN------TDYAGPHTFDVSFQQSSTAKSATWTYSTELKKLYCQIAKTCPIQIKVLTNPPQGAVIRAMPVYKKAEHVTEVVKRCPNHELSREFNDGQIAPPSHLIRVEGNSHAQYVEDS----ITGRQSVLVPYEPP----QVGTEFTTILYNFMCNSSCVGGMNRRPILIIVTLETRDGQVLGRRCFEARICACPGRDRKADEDSIRKQHVTDGTKSSEGTKRPFRQASSHLSQLNSIKKRRSTDEEVFCLPIKGREIYEILVKIKESLELMQFLPQQTIESYRQQQQ----NLLQKQSSLPPQPAFGSSSPTLGK----NKLPSVSQLINPQQRNALTPSGMPGGLTDSLLQSQPFPLPSVTPPMMGGPVPMNTDLSSLSPNNPLQSQLQMVPSSHCTPPPPYPMDNSISSFLLRLGCSACLDYFTAQGLTNIYQIENYNLEDLSRLKIPTEFQHIIWKGIMEYRQTMEFSPPPHILRTSSGTSTVSVGSTEARGERVIDAVRFTLRQTISFPPRDDWTDFSFDLAPDSRRNKQQRIKEEGE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IMZ4-1", "uniprot_id": "Q8IMZ4_DROME", "id": "Q8IMZ4-1", "name": "", "aln": "MSLHKSASFSLTFNQNTSIVSRSNSRTIFEAFKEFLDFWDIGNEVSAESAVRVSSNGAFNLPQSFGNESNEYAHLATPVDPAYGGNNTNNMMQFTNNLEILANNNSDGNNKINACNKFVCHKGTDSEDDSTEVDIKEDIPKTVEVSGSELTTEPMAFLQGLNSGNLMQFSQQSVLREMMLQDIQIQANTLPKLENHNIGGYCFSMVLDEP---PKSLWMYSIPLNKLYIRMNKAFNVDVQFKSKMPIQPLN-LRVFLCFSNDVSAPVVRCQNHLSVEPLTANNAKMRESLLRSE-NPNSVYCGNAQGKGISERFSVVVPLNMSRSVTRSGLTRQTLAFKFVCQNSCIG---RKETSLVFCLEKACGDIVGQHVIHVKICTCPKRDRIQDER-----------------------------QLNSKKRKSVPEAAEEDEPSKVR----------------RCIAIKTEDTESNDSRDCDDSAAEWNVSRTPDGDYRLAITCPNKE---WLLQSIEGMIKEAAAEVLR------------------------------------NPNQENLRRHANKLLSLKKRAYELP-----------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* :: : : : :. :: * :.: :: :. : :: : : : *:: : : . . ::.: . . . ::. :. *: : . .. * . : : ..:*: ::* * : : . * :* .. * : *.: :::. .: * ** *:*** :: *: ::::. : * .: . ::.*: * ** ** . :. .: . *:* * *.:: * :. *: * **:** : . : * *: ::*:*:.**:* *: ::. **. *:::*:: :..:**:** *** ** *:.* *:: .: * : * : :. :* :: ::.: : : * . : : . .* * *:. :*: :.* : . . . *.: :: * ", "identical_positions": 73, "similar_positions": 164, "identity": "10.0%" }, { "cls_id": "homologset.agr.MGI:1330812", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9R0H0-1", "uniprot_id": "ACOX1_MOUSE", "id": "Q9R0H0-1", "name": "Peroxisomal acyl-coenzyme A oxidase 1", "aln": "-------------MNPD--LRKERAAATFNPELITHILDGSPENTRRRREIENLILNDPDFQH-EDYNFLTRSQRYEVAVKKSATMV-----------------KKMREFG--IADPEEIMWFKK------------LHMVNFVEPVGLNYSMFIPTLLNQGTTAQQEKWMHP--SQELQ-IIGTYAQTEMGHGTHLRGLETTATYDPKTQEFILNSPTVTSIKWWPGGLGKTSNHAIVLAQLITRGECYGLHAFVVPIREIGTHKPLPGITVGDIGPKFGYEEMDNGYLKMDNYRIPRENMLMKYAQVK--PDGTYVKPLSNKLT----YGTMVFVRSFLVGSAAQSLSKACTIAIRYSAVRRQSEIKRSEPEPQILDFQTQQYKLFPLLATAYAFHFLGRYIKETYMRINESIGQGDLSE-----------LPELHALTAGLKAFTTWTANAGIEECRMACGGHGYSHSSGIPNIYVTFTPACTFEGENTVMMLQTARFLMKIYDQVQSGKLVGGMVSYLNDLPSQRIQPQQVAVWPTLVDINSLDSLTEAYKLRAARLVEIAAKNLQAQVSHRKSKEVAWNLTSVDLVRASEAHCHYVTVKVFADKLPKIQDRA-----VQAVLRNLCLLYSLYGISQKGGDFLEGNI-ITGAQMSQVNSRILELLTVTRPNAVALVDAFDFKDVTLGSVLGRYDGNVYENLFEWAKKSPLNKTE--VHESYYKHLKP-LQSKL--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P07872-1", "uniprot_id": "ACOX1_RAT", "id": "P07872-1", "name": "Peroxisomal acyl-coenzyme A oxidase 1", "aln": "-------------MNPD--LRKERASATFNPELITHILDGSPENTRRRREIENLILNDPDFQH-EDYNFLTRSQRYEVAVKKSATMV-----------------KKMREYG--ISDPEEIMWFKK------------LYLANFVEPVGLNYSMFIPTLLNQGTTAQQEKWMRP--SQELQ-IIGTYAQTEMGHGTHLRGLETTATYDPKTQEFILNSPTVTSIKWWPGGLGKTSNHAIVLAQLITQGECYGLHAFVVPIREIGTHKPLPGITVGDIGPKFGYEEMDNGYLKMDNYRIPRENMLMKYAQVK--PDGTYVKPLSNKLT----YGTMVFVRSFLVGNAAQSLSKACTIAIRYSAVRRQSEIKQSEPEPQILDFQTQQYKLFPLLATAYAFHFVGRYMKETYLRINESIGQGDLSE-----------LPELHALTAGLKAFTTWTANAGIEECRMACGGHGYSHSSGIPNIYVTFTPACTFEGENTVMMLQTARFLMKIYDQVRSGKLVGGMVSYLNDLPSQRIQPQQVAVWPTMVDINSLEGLTEAYKLRAARLVEIAAKNLQTHVSHRKSKEVAWNLTSVDLVRASEAHCHYVVVKVFSDKLPKIQDKA-----VQAVLRNLCLLYSLYGISQKGGDFLEGSI-ITGAQLSQVNARILELLTLIRPNAVALVDAFDFKDMTLGSVLGRYDGNVYENLFEWAKKSPLNKTE--VHESYHKHLKP-LQSKL--------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q15067-1", "uniprot_id": "ACOX1_HUMAN", "id": "Q15067-1", "name": "Peroxisomal acyl-coenzyme A oxidase 1", "aln": "-------------MNPD--LRRERDSASFNPELLTHILDGSPEKTRRRREIENMILNDPDFQH-EDLNFLTRSQRYEVAVRKSAIMV-----------------KKMREFG--IADPDEIMWFKK------------LHLVNFVEPVGLNYSMFIPTLLNQGTTAQKEKWLLS--SKGLQ-IIGTYAQTEMGHGTHLRGLETTATYDPETQEFILNSPTVTSIKWWPGGLGKTSNHAIVLAQLITKGKCYGLHAFIVPIREIGTHKPLPGITVGDIGPKFGYDEIDNGYLKMDNHRIPRENMLMKYAQVK--PDGTYVKPLSNKLT----YGTMVFVRSFLVGEAARALSKACTIAIRYSAVRHQSEIKPGEPEPQILDFQTQQYKLFPLLATAYAFQFVGAYMKETYHRINEGIGQGDLSE-----------LPELHALTAGLKAFTSWTANTGIEACRMACGGHGYSHCSGLPNIYVNFTPSCTFEGENTVMMLQTARFLMKSYDQVHSGKLVCGMVSYLNDLPSQRIQPQQVAVWPTMVDINSPESLTEAYKLRAARLVEIAAKNLQKEVIHRKSKEVAWNLTSVDLVRASEAHCHYVVVKLFSEKLLKIQDKA-----IQAVLRSLCLLYSLYGISQNAGDFLQGSI-MTEPQITQVNQRVKELLTLIRSDAVALVDAFDFQDVTLGSVLGRYDGNVYENLFEWAKNSPLNKAE--VHESY-KHLKS-LQSKL--------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B6F4-1", "uniprot_id": "A0ACD6B6F4_DANRE", "id": "A0ACD6B6F4-1", "name": "Acyl-coenzyme A oxidase", "aln": "-------------MNPD--ISRERENASFNLEILTNVLDGGAEKTNRRREIESLVIGDPDFQH-EDLNFLSRSERYDAAVRKSAQMI-----------------LKLREYG--ISDPEEIYSYKT------------CVHRGRPEPLDLHLGMFLPTLLNQSSPAQLETFFMP--AWNLE-IIGTYAQTEMGHGTHIRALETTATYDPSTQEFVLNSPTISSIKWWPGGLGKTSNHAIVLAQLYTQGKCHGLHAFITPIRCMKTHMPLPGVVVGDIGPKFGFDEVDNGYLKLENVRIPRENMLMKYAQVE--PDGTYVKPPSDKLT----YGTMVFIRSMIVGESARALSKSCTIAIRYSAVRHQSELRPGEPEPQILDYQTQQYKLFPLLATAYAFHFVGQYMNKTYHRISGDISLGDFSE-----------LPELHALSAGLKAFTTWAANTGIEVCRMSCGGHGYSRCSSLPDIYVTFTPTCTYEGENTVMMLQTARYLVKSYKQARAGQQLTGIVSYLNESQS-RIQPHSVSSRPTVVNINDLVSLVEAYKFRAAKLVEVAAKNLQLELQHSKSNEDAWNNTSIDLVRASDAHCHYVVVKLFAAKLSEIGDKA-----VHSVLSTLALLYALHGVAQNSGDFLKAGL-LSVSQLDQISQRLKGLLLEIRPNAVALVDAFDYRDEMLNSSLGRYDGNVYEHMFEWAKKSPLNHTE--VHESHNKYLKP-LRSKL--------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W2G9-1", "uniprot_id": "Q9W2G9_DROME", "id": "Q9W2G9-1", "name": "Acyl-coenzyme A oxidase", "aln": "--MASSTSVIPTTVNPD--LQKERDAASFNSEEFAAWWAGGEEVLKFNRGVREYMEKDVDLSEMLQLQNKTHEEIIEFSTRGAIEGA-----------------KKLRRLQEERNPGGDVYWPN------LYDAQVMWGLVPGGNPFGVMYVMLVKALQAQCTPEQYEEFGKR--VELFE-ICGTYAQTELGHGTYLRGLETRADFDRKTDQFVLNTPNISSYKWWPGGLGHSSNHCLVMAQLYIDGDCKGPHMFFIQVRDEDTHEPLPGVHIGDIGKKMGFIGVNNGFLGLKNVRIPRTRMLMRHAQVK--ADGSYVSSPTNVLT----YFAMVRTRCVIAKNNAVMLASAATIATRYSAVRRQSPINPNEREPQIMDHVTQQMKLFPEIATSVAYRKAGDYLWNLYDVTIEDIENGKYER-----------LPELHSLSCALKVTCSMDSASGVEKLRLACGGHGFLTSSNMSSIYVSATAACTYEGENTVLLLQIGRFLMKTWRAALTGAPLPPTVRYLAEVQKNPEFGTWTG---------SWENMVKAMQYAAANRTQLAFRSLSKRMSRGETEANAANHTGIEFTQAAELHGRAFVFSAFYEAVTGPQSKT-RSANFNRVLENLLELYLVKETLNQMGHLLRFIN-LTDTDLSGLQDRLETVLTKLRPDAVAIVDGFDFSDLQLNSTLGSYDGNAYERIFDAALKNPMNQKA--VPKYFHEILRPFMKSNI--------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W2G8-1", "uniprot_id": "Q9W2G8_DROME", "id": "Q9W2G8-1", "name": "Acyl-coenzyme A oxidase", "aln": "--MSHIKNLIPSTVNPD--LQKERAAAEFHVEEFSAWWHGGQDKLKKKREIEKAIFSDLEDGYGLNHEYMSHEEVYNSTVKKVAEAA-----------------VKLKALQNKLNPGGTDIWPGG-----LFNAQS-FGLFPANHPIATHITMFVDVIKGQGTAEQVEKWGKA--AENCN-IIGTYAQTELAHGTNVRGLATRADFDPKTDEFVLNTPNLEAYKWWPGGLGHTANHAMVVAQLYIADVHHGVQMFIVPLRDSETHMPLPGVDIGEIGKKLGMASVNQGFLGLNHVRIPRTNMLMKFAKVE--RDGTFKASPASRIN----YLTMVYTRCLIVSQNSTLLLAAATIATRYSAVRRQSPIEPNQPEPQIIDHVTQRLKLFPEIATGIAYHLATEYMWEMYAQTVQEANNGKFER-----------LPDMHILSCALKVLCTTDGCAGIEKLRLSTGGHGYLIAANLSNIYGNAVAAYTYEGENTVLLLQIGRALVKAWASFVDKKPLSASYSYFASSMQLKEFPKWDD---------SWQCIIKALQYTAAHKTRIAFENLANRMASGQSQGVAANNTGIELTRAAELHGRQFVCQTFLEQITGAKAQK-RSPALNKILENVLELFLVQTVLNNLNDILRFIK-LSDADLRSLQKRLEDSLAQFRPNAVAICDGFEFHDRVLNSVLGSYDGNVYPRLFDSAKRSTMNQKP--VQTSFETYLKPLMKAKL--------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q7KML2-1", "uniprot_id": "ACOX1_DROME", "id": "Q7KML2-1", "name": "Acyl-coenzyme A oxidase 1", "aln": "--------MPAKPVNPD--LQKERSTATFNPREFSVLWAGGEERFKEKKALEKLFLEDPALQDDLPISYLSHKELYEHSLRKACIIG-----------------EKIRKLRADGEDG--VDTYNA-----LLGGSLGSAILKEGNPLALHYVMFVPTIMGQGTMDQQVEWLSK--AWDCE-IIGTYAQTELGHGTFLRGLETRADYDASTQEFVINTPSLSAYKWWPGGLGHTANHAVVVAQLYTKGEFRGLAPFIVQLRDSDTHRPMPGIDIGDIGTKLGMKGVNNGYLGLKNVRVPLNNMLMKNQQVL--PDGTYVAPKNSVLT----YGTMMFVRCALIRDTAQSLAKASTIATRYSAVRRQSPIDPNQPEPQIMDHTTQQLKLFPQIAKAIVFKTTGDGIWNMYNVISGEIEQGNLDR-----------LPEMHALSCCLKAICSADAAAGVETCRLSCGGHGYMDCSNFPTIYGMTTAVCTYEGENTVMLLQTARYLVKVYGQALNGEKLVPTVSYISDAINQTKFVNFDG---------SLRSIVKAFQFVAANKTRIAYEQIELRRKQGYGTEVAANLCGTFLTAAADLHGRAFLAQTAYTELL-ALSRE-VSPELAEVLKVVLELYLVDACLNRIGDFLRFID-LTDQDVTKLEVRLENCLKRFRPNAVSLVDSFDLHDRVLDSALGAYDGNVYEHIFESTKKNPLNKEP--VNGAFHKYLKPFMKAHL--------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W3U0-1", "uniprot_id": "Q9W3U0_DROME", "id": "Q9W3U0-1", "name": "Acyl-coenzyme A oxidase", "aln": "-----------MSVNAD--LQRERAAATLDSEDFARWWAGGSGQLEERRALERRFYEDPDFAEPVHPSCLSYKERYEQTVARSTRFL-----------------AKLRQWQREKQPQLQLSVNMLRDFRLLLSGSLGTGLFQQSFPLRVHFSMFMTTLLSQGTEEQQAQWLNR--SWHMDGVLGTYAQTELGHGTFVRGLETRADYDPITQEFILNTPTQSSYKWWPGGLGNTANVAIVLAQLYVKGKHYGLQSFVVRIRDERTHEPLTGVDVGDIGPRLGGNGVNNGFLGLRDVRIPRNQMLMKNAQVL--TDGTFVQGRPPLLL----YGTMVYVRVITVKDVLFGLLQAATIATRYSVVRRQSRINSDQPEVSVLDHITQQAKILPQIARGVSYRLVSDWLWRFYEDVLRQLEDESTKGR--------NSLPELHALSCCLKAVATDEASEGVDLLRKSCGGHGFLSSANFDSIYGLTAATYTYEGEYTVLLLQTARFLVRQYADSLKRKVLPSSVSYLRDTAR---LIWGKN---------LVANCVRALEISAMEQVRDAWQTQKMHQSGKVSPEMASNLAGRQLTSAAIAHAHAFFTRNALEQVEALRKKGDLSPNVSLILGQLVELFVIDTFLRQSGCVLRWNNGITGTQLRFVERRFEELLAKLRPNAVALVDGFDFHDRVLGSTLGCHDGRVYERLMEEARRNPINQEP--VNSSFHNHLLPMMRGKL--------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P13711-1", "uniprot_id": "ACOX_YEAST", "id": "P13711-1", "name": "Acyl-coenzyme A oxidase", "aln": "MTRRTTINPDSVVLNPQKFIQKERADSKIKVDQVNTFLESSPERRTLTHALIDQIVNDPILKTDTDYYDAKKMQEREITAKKIARLASYMEHDIKTVRKHFRDTDLMKELQANDPDKASPLTNKDLFIFDKRLSLVANIDPQLGTRVGVHLGLFGNCIKGNGTDEQIRYWLQERGATLMKGIYGCFAMTELGHGSNVAQLQTRAVYDKQNDTFVIDTPDLTATKWWIGGAAHSATHAAVYARLIVEGKDYGVKTFVVPLRDPSTFQLLAGVSIGDIGAKMGRDGIDNGWIQFRNVVIPREFMLSRFTKVVRSPDGSVTVKTEPQLDQISGYSALLSGRVNMVMDSFRFGSKFATIAVRYAVGRQQFAPRKGLSETQLIDYPLHQYRVLPQLCVPYLVSPVAFKLMDNYYSTLDELYNASSSAYKAALVTVSKKLKNLFIDSASLKATNTWLIATLIDELRQTCGGHGYSQYNGFGKGYDDWVVQCTWEGDNNVLSLTSAKSILKKFIDSATKGRFDNTLDVDSFSYLKPQYIGSVVSG-------EIKSGLKELG-DYTEIWSITLIKLLAHIGTLVEKSRSIDSVSKLLVLVSKFHALRCMLKTYYDKLNSRDSHIS-DEITKESMWNVYKLFSLYFIDKHSGEFQQFKIFTPDQISKVVQPQLLALLPIVRKDCIGLTDSFELPDAMLNSPIGYFDGDIYHNYFNEVCRNNPVEADGAGKPSYHALLSSMLGRGFEFDQKLGGAANAEILSKINK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*.: : :** : :. . .. : : . * . : : : :: . :: : : : * : . : * :* **:.**: : * * * :* .: *::::* : *** ** .:::. . * *:* . * *. :* *. :.*: :*:** ::* :::*:: : . :* ** : :* **: : * ::: * . .*** **:. *:* . * .::*. :: :::* :. : * . . * ::. :. **. : :: * : ****: .: * . *:**: .*: * .: ::: : . . . : . : : . :. .: * : : : : *: : .. . . . . :. :. * * :.:.: *.*: * *.* :* .** * . :: . .. . . * . : : ", "identical_positions": 82, "similar_positions": 168, "identity": "10.83%" }, { "cls_id": "homologset.agr.MGI:1330815", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P01619-1", "uniprot_id": "KV320_HUMAN", "id": "P01619-1", "name": "Immunoglobulin kappa variable 3-20", "aln": "ME---TPAQLLFLLLLWLPDTTGEIVLTQSPGTLSLSPGERATLSCRASQSVSSS---YLAWYQQKPGQAPRLLIYGASSRATGIPDRFSGSGSGTDFTLTISRLEPEDFAVYYCQQYGSSP------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0C4DH25-1", "uniprot_id": "KVD20_HUMAN", "id": "A0A0C4DH25-1", "name": "Immunoglobulin kappa variable 3D-20", "aln": "ME---TPAQLLFLLLLWLPDTTGEIVLTQSPATLSLSPGERATLSCGASQSVSSS---YLAWYQQKPGLAPRLLIYDASSRATGIPDRFSGSGSGTDFTLTISRLEPEDFAVYYCQQYGSSP------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P04433-1", "uniprot_id": "KV311_HUMAN", "id": "P04433-1", "name": "Immunoglobulin kappa variable 3-11", "aln": "ME---APAQLLFLLLLWLPDTTGEIVLTQSPATLSLSPGERATLSCRASQSVSS----YLAWYQQKPGQAPRLLIYDASNRATGIPARFSGSGSGTDFTLTISSLEPEDFAVYYCQQRSNWP------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0A0MRZ8-1", "uniprot_id": "KVD11_HUMAN", "id": "A0A0A0MRZ8-1", "name": "Immunoglobulin kappa variable 3D-11", "aln": "ME---APAQLLFLLLLWLPDTTGEIVLTQSPATLSLSPGERATLSCRASQSVSS----YLAWYQQKPGQAPRLLIYDASNRATGIPARFSGSGPGTDFTLTISSLEPEDFAVYYCQQRSNWH------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P01624-1", "uniprot_id": "KV315_HUMAN", "id": "P01624-1", "name": "Immunoglobulin kappa variable 3-15", "aln": "ME---APAQLLFLLLLWLPDTTGEIVMTQSPATLSVSPGERATLSCRASQSVSSN----LAWYQQKPGQAPRLLIYGASTRATGIPARFSGSGSGTEFTLTISSLQSEDFAVYYCQQYNNWP------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A087WSY6-1", "uniprot_id": "KVD15_HUMAN", "id": "A0A087WSY6-1", "name": "Immunoglobulin kappa variable 3D-15", "aln": "ME---APAQLLFLLLLWLPDTTGEIVMTQSPATLSVSPGERATLSCRASQSVSSN----LAWYQQKPGQAPRLLIYGASIRATGIPARFSGSGSGTEFTLTISILQSEDFAVYYCQQYNNWP------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A075B6H7-1", "uniprot_id": "KV37_HUMAN", "id": "A0A075B6H7-1", "name": "Probable non-functional immunoglobulin kappa variable 3-7", "aln": "ME---APAQLLFLLLLWLPDTTREIVMTQSPPTLSLSPGERVTLSCRASQSVSSS---YLTWYQQKPGQAPRLLIYGASTRATSIPARFSGSGSGTDFTLTISSLQPEDFAVYYCQQDYNLP------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0C4DH90-1", "uniprot_id": "A0A0C4DH90_HUMAN", "id": "A0A0C4DH90-1", "name": "", "aln": "ME---APAQLLFLLLLWLPDTTGEIVMTQSPATLSLSPGERATLSCRASQSVSSS---YLSWYQQKPGQAPRLLIYGASTRATGIPARFSGSGSGTDFTLTISSLQPEDFAVYYCQQDYNLP------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0C4DH55-1", "uniprot_id": "KVD07_HUMAN", "id": "A0A0C4DH55-1", "name": "Immunoglobulin kappa variable 3D-7", "aln": "MEPWKPQHSFFFLLLLWLPDTTGEIVMTQSPATLSLSPGERATLSCRASQSVSSS---YLSWYQQKPGQAPRLLIYGASTRATGIPARFSGSGSGTDFTLTISSLQPEDFAVYYCQQDYNLP------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6AKA7-1", "uniprot_id": "A0A8I6AKA7_RAT", "id": "A0A8I6AKA7-1", "name": "", "aln": "MEC-----------VFIISGSTGDIVLTQSPA-LAVSLGQRATISCRASQSVSTSSYNLMHWYQQKPGEQPKLLIYDASNLASGIPVRFSGSGSGTDFTLTINPVQADDIATYYCQQSRELPPTVVQG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A140T8P0-1", "uniprot_id": "A0A140T8P0_MOUSE", "id": "A0A140T8P0-1", "name": "", "aln": "METD---TLLLWVLLLWVPGSTGDIVLTQSPASLAVSLGQRATISCRASKSVSTSGYSYMHWYQQKPGQPPKLLIYLASNLESGVPARFSGSGSGTDFTLNIHPVEEEDAATYYCQHSRELP------", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** :: :..:* :**:**** *::* *:*.*:** **:***: : ******* *:**** ** :.:* ******.**:***.* :: :* *.****: . ", "identical_positions": 54, "similar_positions": 29, "identity": "42.19%" }, { "cls_id": "homologset.agr.MGI:1330818", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VD61-1", "uniprot_id": "Q9VD61_DROME", "id": "Q9VD61-1", "name": "Sulfhydryl oxidase", "aln": "--------MIRLLKTLLYCLLLISPADVLGRLNARKSANEASLYSDTDNVIMLDIESLRPALNLKNS-KLVQFLNSFCGDCHRFAPVFKTLSRDLYKWRRILRIYAVDCAQERNAQLCREFNIRQTPSLRFFGPDMRKNDDVLGAVIPGQDPEFISSTLAELVSQNDYGPGQPN-------FRPLKATDYEIFQDQ---DGETPIQFVALVLQPKNSK-------------IGRDTLLELLPFKELSVR--IIEDSQIFNEFGLGPDDQKLAIVDRNGTAQYLTPSSDSSEAYASTIGDFLKNRNIQPDPPLPIAVAPNFTEFLDHQNQAILTKVLTPPLQVYRADLEQAIDKLLHIELRKWVLLEGNSLNALKNIIKIFRYLNPLNKDGKLLLTDLDNSLSSKQ--SIKGADFGDLVDSLENGR-RVFKARR-YVGCIGSRPLLRSFTCSMWTLFHHLTVEAAKPPNYFEAGS-----ILKTFHGFAKYFFGCTDCSEHFQQMAIRRNLTSVKTHDEEILWLWAAHNEVNARIAGDSTEDPKFPKIQFPSAENCPTCRSND----SEWRTDEVLKYLKQLYDINNVSFYGLPTP-QGYD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8IMY4-1", "uniprot_id": "Q8IMY4_DROME", "id": "Q8IMY4-1", "name": "Sulfhydryl oxidase", "aln": "---------MNPNDTLSAFSLLLC---VL-ILSAGRGE---LLFNADDNVVQLDFASFESGLSEPTSGKLVQFFNGFCEESQNFIPAFKNLSRKLYKWHRLLKVHVLDCGKDENDMICSIYSIRKTPTLRYFPPSYKLAPDNLGTEITHRNPKEIQSKLALNLQKLDYFKMFKRQDNVAHIFQTHKDIEYVAFVFQMCLDHFLPHLETGNSMEEKYASQGDCNEDNPIVSLIGRNTLLELLPYRKVVVR--IFDNHDVYNKFGISPVPNLVVLVNKAGKLLFLTPEMDSSKAYVAAIKQFLIFVDLKPQKPLPKTPPANISEALRYE---IFEQHKHHPSRIYRADLERAIDQILNVKFPGTTHFAGAKIVVLRNFVKLIYNSSPLKPEAREKLANLYYSLHVKK--QLSGVGFKNLLLKSVKD--YVFDGKQ-YVGCIASRPSLRGFNCSLWVLFHYLSVESKK----LKPKS-----VLLVFLGYVRFFMNCKECDMKISEFKKLRPIANVTNDDEQILWLWEAHNYVNKQLAGDSTEDPKFPKIQFPSERDCPKCRNNA----TEWRTEEVLHYLKGIYTLKNLSWFGMSSGKHAIE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VD62-1", "uniprot_id": "Q9VD62_DROME", "id": "Q9VD62-1", "name": "Sulfhydryl oxidase", "aln": "--------MVWHFWVPYLTCIILILIVQEGHSKQRCLDEEPPLYSKEDNIHVVVGASLKKILAEPAMGKLVQFLNSYCGNCRRFAHTFRKMAVDLQKWNRVLRIYAVDCARLENVKLCRDFRITLTPTIRYYPSKFQRIRHGIGTDIETTIPSEIADQLIESLSENDYSESKGVKP----IFDPIEPGNKLNDIYEQFDNKVTYILLVHPVD-------------------MGIETILNMLPYPDVGVR--IIKDAEMFAQFGLKPCKQMVALLNRSGKAQLIKPAGKSSSAYVESVAGLLHQNGHTSMPTLPPAEPEYILSEGYDA--FIVDYVLNSTKVLFQADLEQAIYQFLHVEIPKTAFISGFKFKALRHIIRLFRRFNVLNRDGRRMLNSLVNHLFEVT--EITGEEFRDVVDDLQTRLDPIFAEQQ-YVGCLGSTPHTRRFSCSLWTLFHYFTVLAAQMK-VYPPSS-----VTIGLYGLAKFFYDCKDGSMYFVKLAKRMNIAKVRTHDEEILWLWEAHNEVNEKLAGDASGDPRFPKVQFPERKHCPDCYTHS----GEFDRDEVLKYLKRVYNLSYLSGDAEPHSRRSNECKSKKKYLQK-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q6IUU3-1", "uniprot_id": "QSOX1_RAT", "id": "Q6IUU3-1", "name": "Sulfhydryl oxidase 1", "aln": "--MRRCGRHSGPPSLLLL---LLLLPPLLLSVPGAYAARLSVLYSSSDPLTLLDADTVRPAVLGSSSAWAVEFFASWCGHCIAFAPTWKELANDVKDWRPALNLAVLDCADETNSAVCREFNIAGFPTVRFFKAFSKNGT-GTALPAAGANVQTLRMRLIDALESHRDTWPPACPP-----LEPAKLKDINEFFTRSKAEYLALIFEREDSY-------------------LGREVTLDLSQFHAVAVRRVLNSESDVVSKFAVTDFPS-CYLLLRNGSVSRVPVLVESRPFYTSYLRGLPGLTREAPPTTAAPVTPDKIAPTVWKF---------ADRSKIYMADLESALHYILRVEVGKFSVLEGQRLVALKKFVAVLAKYFPGQPLVQNFLHSINDWLQKQQKKKIPYSYFKAALD--SRKENAVLAEKVNWIGCQGSEPHFRGFPCSLWVLFHFLTVQAHRYSEAHPQEPADGQEVLQAMRSYVQSFFGCRDCANHFEQMAAAS-MHQVKSPSNAVLWLWTSHNRVNARLSGALSEDPQFPKVQWPPRELCSACHNEVNGQVPLWDLGATLNFLKAHFSPANIVRDPPAPGPASRRGTQDPEASPNLVMDTLKLETG--------NSVLGHEQAASAASPGATALDVPAGKPEAS----GPQELNAGLSMGGASPGQGPPEHTEELLRDVQENAQGQQHLSKRDTEALLLPEV--------NHLQG-----PLAPRRGGHSPKQLASILEGE-PEALAIQGRRQWLQVLGGGVSFLDISLCVGLYSVSFMGLLAMYTYFRARMRTPKGHVSYPTA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BND5-1", "uniprot_id": "QSOX1_MOUSE", "id": "Q8BND5-1", "name": "Sulfhydryl oxidase 1", "aln": "--MRRCGRLSGPPSLLLL---LLLLSPLLFSGPGAYAARLSVLYSSSDPLTLLDADSVRPTVLGSSSAWAVEFFASWCGHCIAFAPTWKELANDVKDWRPALNLAVLDCAEETNSAVCREFNIAGFPTVRFFQAFTKNGS-GATLPGAGANVQTLRMRLIDALESHRDTWPPACPP-----LEPAKLNDIDGFFTRNKADYLALVFEREDSY-------------------LGREVTLDLSQYHAVAVRRVLNTESDLVNKFGVTDFPS-CYLLLRNGSVSRVPVLVESRSFYTSYLRGLPGLTRDAPPTTATPVTADKIAPTVWKF---------ADRSKIYMADLESALHYILRVEVGKFSVLEGQRLVALKKFVAVLAKYFPGQPLVQNFLHSINDWLQKQQKKRIPYSFFKAALD--SRKEDAVLTEKVNWVGCQGSEPHFRGFPCSLWVLFHFLTVQANRYSEAHPQEPADGQEVLQAMRSYVQFFFGCRDCADHFEQMAAAS-MHQVRSPSNAILWLWTSHNRVNARLSGALSEDPHFPKVQWPPRELCSACHNELNGQVPLWDLGATLNFLKAHFSPANIVIDSSASRHTGRRGS--PEATPELVMDTLKLESR--------NSVLGHEQAASAESPGATALDVPAEKPEAS----GPQELYTGLRMGGASPGQGPPERMEDHQRDMQENAPGQQHLSKRDTEALFLPEV--------NHLQG-----PLELRRGGRSPKQLAPILEEE-PEALAIQGQGQWLQVLGGGISHLDISLCVGLYSVSFMGLLAMYTYFRARLRTPKGHASYPTA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00391-1", "uniprot_id": "QSOX1_HUMAN", "id": "O00391-1", "name": "Sulfhydryl oxidase 1", "aln": "--MRRCNSGSGPPPSLLL---LLLW---LLAVPGANAAPRSALYSPSDPLTLLQADTVRGAVLGSRSAWAVEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALDCAEETNSAVCRDFNIPGFPTVRFFKAFTKNGS-GAVFPVAGADVQTLRERLIDALESHHDTWPPACPP-----LEPAKLEEIDGFFARNNEEYLALIFEKGGSY-------------------LGREVALDLSQHKGVAVRRVLNTEANVVRKFGVTDFPS-CYLLFRNGSVSRVPVLMESRSFYTAYLQRLSGLTREAAQTTVAPTTANKIAPTVWKL---------ADRSKIYMADLESALHYILRIEVGRFPVLEGQRLVALKKFVAVLAKYFPGRPLVQNFLHSVNEWLKRQKRNKIPYSFFKTALD--DRKEGAVLAKKVNWIGCQGSEPHFRGFPCSLWVLFHFLTVQAARQNVDHSQEAAKAKEVLPAIRGYVHYFFGCRDCASHFEQMAAAS-MHRVGSPNAAVLWLWSSHNRVNARLAGAPSEDPQFPKVQWPPRELCSACHNER-LDVPVWDVEATLNFLKAHFSPSNIILDFPAAGSAARRDVQNVAAAPELAMGALELESR--------NSTLDPGKPEMMKSPTNTTPHVPAEGPEAS----RPPKLHPGLR---AAPGQEPPEHMAELQRNEQEQPLGQWHLSKRDTGAALLAESRAE----KNRLWG-----PLEVRRVGRSSKQLVDIPEGQ-LEARAGRGRGQWLQVLGGGFSYLDISLCVGLYSLSFMGLLAMYTYFQAKIRALKGHAGHPAA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0UXN0-1", "uniprot_id": "B0UXN0_DANRE", "id": "B0UXN0-1", "name": "Sulfhydryl oxidase", "aln": "MARRGCGATSCYTTKTKLNSFYSFLCAFITCVSLCPVLCEAGLYTASDQVIVLTPENVDSTLFNNTAALLVEFYATWCGHCIAFSPVWKSLARDIKEWKPAVDLAAIDCANESNRKVCTNFGITGYPSIKFFHAYSSIGSRGLEVRGFSRDVRGLRQYIIENLELHTEAWPPACPP-----LETASEAEVHHFFPANNVKYLALVFENKKSY-------------------VGREVTLDLLQYENIAVRRVLDTETNLVSRFGVTEFPS-CYLYDSSGNITRLKVLKEARTFYSYALQRLPGVVRTGKHQTPITELIKNSTLQEWRP---------FNKSRVYMSDLESALHYSLRVELSSHTSISGDDLIALKKYINVLAKYFPGRPSVKSALQAVDSWLQSQKGTEIKYSDFRDVLDNVVQTSDAVLPEGVQWVGCQGSQARYRGYPCAVWTLFHVLTVQAKEMGSTVSEP----QEVLLAMRGYVSSFFGCRPCATHFEAMAAES-MDQVNSLSGAVIWLWSRHNRVNNRLAGDLSEDPHFPKIQWPSPELCPSCHGVTIIGDHNWIKDEVPQFLQNYFSSSRILNDYLQDETQALIQQRNRLTAARMEKEAGRGADRRARDIFDNNPADEPQEEEEEEEEEEPTFEEQAVEPYPAGLEGAPGADQAPWEKPQPLSSQRKPKIVGMKLREAQEDIVDLDYFVSQHYKAKALRAAAMSGVVRRRSLQKKEDVEDLQFEGGWRVKRDLGSQEENFGIEPYPRAQSKHWMSLLSVGFSRLDVSLCVLLYLLSTMCLLAMYMYFKLRIKLRSAKVSLP--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:. * : : .. : *:* :* .. * .:: :: .: *. : : .:**. * :* : * *::::: . : : :. : . . : . :* :. *:: . : ** : : :: .*.: . : *. : .: * : : . :: :*** *: *.::. : * : .*:: : :: . : * : * : * : :: ::** .* . * : *::*.*** ::* : . : : . . * .* : : : * . . ::*** ** ** :::* : **:***:*:* . *. * : . ::*: : : . ", "identical_positions": 61, "similar_positions": 128, "identity": "7.45%" }, { "cls_id": "homologset.agr.MGI:1330819", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q65Z14-1", "uniprot_id": "OSMR_RAT", "id": "Q65Z14-1", "name": "Oncostatin-M-specific receptor subunit beta", "aln": "MAFSVVLHQVTFLLAVLSLRTSQSKVLGEP-LQLTPEIHTVSLQSALQEANLEWTVPTFS-HQELNIVFQIEISRMRTSNTIWVGNYSTTVKHEETVH-WKWTSDIPLECATHFIRIRAMVDDAQYPPQSSWSNWSSWKEVNAQVSVPPDTLLIFPEDRLLEEGSNVTICLMIGQNLYNVSCKLQEEPIRGEQLDSHLSLIKLNNVVFLNNAGTNINCKAMNG--TKNTFGTVLFVSKVLEEPKNFSCETRDFKTLNCLWEPGIDTTLSWHKQRSQHYTLYESFSGRREVSNHRNSHTWQITEDSQETYNFTLTAENNLRKRSVSISFNLTHRVHPKAPHDVTLKTVGATKAHMTWKVPSRGD-YTLLCQVELQCEGEVIHEHNVSVHTSANYLFSDLEPDTEYKACVRCASANHFWKWSDWMQKKFRTPEAAPSEALDVWRDVRTENGRHVVTLFWKPLLKSQANGKIISYNIVVENEANPTESEQYSVRAPALGTNLSLDLHPYKIHISANNSAGASPESLVVLSSHSGHEEVHEKTIKGIKNGFNISWEPVSGDAIGYVVDWCAHSQTQRCDLQWKNVGPNITSTIITSDAFEPGVRYNFRIFERSVEENVRLVEKQRGYTQELAPSVNPGVTIHNLTPNSFSLKWQDYASDFQSGFIKGYLVYLKSKELQCNPNWERTVLSDKSVLCKYDVDDPETKTLTVENLRPESLYEFLVTPYTSAGQGPNETYTKVTTPDVRSHMLLQIILPMT---LGVFLSIIVCYWKSQWVKEKCYPDIPNP----YKSSILSLIKSKKNPH-LIMNVK----DCIPDVLEVINKAEGSKTQCVGSGK------LHTEDVPTKP---PLVPTEKDSSGPMPFVFLENFTYDQSAFDSGSHGFIPGPLKNTPHQLGLLAPPNKLQNVLENDYMKSLVESPTEETSLIYVSQLASPICGDKDSLVTNPPMPVHGSEYKKQMALPGSLTSASLKENN-LTS-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70458-1", "uniprot_id": "OSMR_MOUSE", "id": "O70458-1", "name": "Oncostatin-M-specific receptor subunit beta", "aln": "MAFSVVLHP-AFLLAVLSLRASRSEVLEEP-LPLTPEIHKVSFQLKLQEVNLEWTVPALT-HEELNMIFQIEISRLNISNTIWVENYSTTVKREEAVR-WNWTSDIPLECVKHFIRIRALVDDTKSLPQSSWGNWSSWKEVNAKVSVEPDKSLIFPKDKVLEEGSNVTICLMYGQNVYNVSCKLQDEPIHGEQLDSHVSLLKLNNVVFLSDTGTNINCQATKG--PKRIFGTVLFVSKVLEEPKNVSCETRDFKTLDCSWEPGVDTTLTWRKQRFQNYTLCESFSKRCEVSNYRNSYTWQITEGSQEMYNFTLTAENQLRKRSVNINFNLTHRVHPKAPQDVTLKIIGATKANMTWKVHSHGNNYTLLCQVKLQYG-EVIHEHNVSVHMSANYLFSDLDPDTKYKAFVRCASANHFWKWSDWTQKEFSTPETAPSQALDVWRQVWSENGRRIVTLFWKPLLKSQANGKIISYNIVVENEAKPTESEHYCVWAPALSTNLSLDLQPYKIRITTNNSMGASPESLMVLSNDSGHEEVKEKTIKGIKDAFNISWEPVSGDTMGYVVDWCAHSQDQRCDLQWKNLGPNTTSTTITSDDFKPGVRYNFRIFERSVEHKARLVEKQRGYTQELAPLVNPKVEIPYSTPNSFVLRWPDYDSDFQAGFIKGYLVYVKSKEMQCNQPWERTLLPDNSVLCKYDINGSETKTLTVENLQPESLYEFFVTPYTSAGPGPNETFTKVTTPDARSHMLLQIILPMT---LCVLLSIIVCYWKSQWVKEKCYPDIPNP----YKSSILSLIKSKKNPH-LIMNVK----DCIPDVLEVINKAEGSKTQCVGSGK------LHIEDVPTKP---PIVPTEKDSSGPVPCIFFENFTYDQSAFDSGSHGLIPGPLKDTAHQLGLLAPPNKFQNVLKNDYMKPLVESPTEETSLIYVSQLASPMCGDKDTLATEPPVPVHGSEYKRQMVVPGSLASPSLKEDNSLTSTVLLGQGEQ--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99650-1", "uniprot_id": "OSMR_HUMAN", "id": "Q99650-1", "name": "Oncostatin-M-specific receptor subunit beta", "aln": "MALFAVFQT-TFFLTLLSLRTYQSEVLAER-LPLTPVSLKVSTNSTRQSLHLQWTVHNLPYHQELKMVFQIQISRIETSNVIWVGNYSTTVKWNQVLH-WSWESELPLECATHFVRIKSLVDDAKFPEPNFWSNWSSWEEVSVQDSTGQDILFVFPKDKLVEEGTNVTICYVSRNIQNNVSCYLEGKQIHGEQLDPHVTAFNLNSVPFIRNKGTNIYCEASQGNVSEGMKGIVLFVSKVLEEPKDFSCETEDFKTLHCTWDPGTDTALGWSKQPSQSYTLFESFSGEKKLCTHKNWCNWQITQDSQETYNFTLIAENYLRKRSVNILFNLTHRVYLMNPFSVNFENVNATNAIMTWKVHSIRNNFTYLCQIELHGE-GKMMQYNVSIKVNGEYFLSELEPATEYMARVRCADASHFWKWSEWSGQNFTTLEAAPSEAPDVWRIVSLEPGNHTVTLFWKPLSKLHANGKILFYNVVVENLDKPSSSELHSIPAPANSTKLILDRCSYQICVIANNSVGASPASVIVISADPENKEVEEERIAGTEGGFSLSWKPQPGDVIGYVVDWCDHTQDVLGDFQWKNVGPNTTSTVISTDAFRPGVRYDFRIYGLSTKRIACLLEKKTGYSQELAPSDNPHVLVDTLTSHSFTLSWKDYSTESQPGFIQGYHVYLKSKARQCHPRFEKAVLSDGSECCKYKIDNPEEKALIVDNLKPESFYEFFITPFTSAGEGPSATFTKVTTPDEHSSMLIHILLPMV---FCVLLIMVMCYLKSQWIKETCYPDIPDP----YKSSILSLIKFKENPHLIIMNVS----DCIPDAIEVVSKPEGTKIQFLGTRK------SLTETELTKPNYLYLLPTEKNHSGPGPCICFENLTYNQAASDSGSCGHVPVSPK-APSMLGLMTSPENVLKALEKNYMNSLGEIPAGETSLNYVSQLASPMFGDKDSLPTNPVEAPHCSEYKMQMAVSLRLALPPPTENSSLSSITLLDPGEHYC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IE17-1", "uniprot_id": "A0A0R4IE17_DANRE", "id": "A0A0R4IE17-1", "name": "", "aln": "------MQGWVTLAVLLSLGAEHSHGQNGLGELAVPRGLSLQPDLPTQTLTLTWQSDS--------SLFDIEIFHTEFMNVVLNETVAVNTDPVTGQHSWTWHSPLPLQCTSHSVQIRARNQQSISP-------WSPLETIPGSDIPERSGPNMYPQDKVVLVGSNMTFCCIVKEKDSFKSIKYGDREMSATRLSRRAYAITVNNQPSSNTTGTNVFCIVQKLTAVDELITGAVVFVGYPPGDKELVCETRDLASAKCSWKKGRDTRLKKRNSR-TNYTLNGRVCG-----EANEGKSWECSSEVWEKN-WTLVARNPIGTIQLTDSAQITDRVHLLAPVNVMADPKAWNATLRWNWTVEAYKKLEMICQMKLISR-QLSSTRNYSGTGLSSVVLEDLWPDVDYTVTVRCASKQSFWKWGDESAPCRIRTKMDFPDAPDVWIWMDSSNTG---RVFWKPLSVSESHGALISYEVFRSGLT-PVVLSPGNISYPIMPD----SGSDITVSVAARNPKGLSKASSATAPAYRADSQLSVSKLLGTDGRFDLSWQPSANASRGYVVEWVPSSCSGLCPVQWGKVPETNNSFTIERESLEEGVKFTVSVFALSAGSPS-LLQRWQGYSQEMIPSRSVRELSANQTGSNVLLSWKPAEMDYQRGFILGYNIYMAN---------------AARLDLIANLSDPEVRSYRLKGLS-LSSYKFIVKAYTSAGEDAGTMVSIKMEMDTADMLFVGILVPLVSMFSCIILISICCYKKRAWVKKAFYPEIPGPKVPGNWSSPQGPLDMKPSPHSLVQIVESPEWDITKESLVSVPEEEENENMEVDTDSDEPALLKYYNQVVGHGSRSNQISDSSGSSTASVDSTQTEITYAGIQSPTSSQGAHSGGYR---PQMQPSENPDEPQDQLDDDDDDGLNTGYKPQCSWQMDSPEAENFSG-----SLGSPTSITSSQFLIPESSEEKPQSSSSWFHSFLSGKS---------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: . : .:*** : :*. .* .:. : * * * :*:*:* : . *.: . :.... : *.* * :**:*..* ::*:: ::: **. : : . . ::*:*::: *:*:*:* : : * . : . :*. : :.:*. ***: * . : . .:.. *:. ***.*: : .* *. * ** * :. *** .. .: .*: :. * :** *.* : . .:. ::*.**: * .* . . : . . . :**::* * * .. .:.:* * ..* . ****. . ****.: : .:* *** : . :***** .::* :: *::. .. * . : * . : : :.*. * * * . . ..:: . : * .. *.:**:* .. ****:* : .** :: . .* * : :. **:: . :: *. *::: **:**: * . * .. * * : * *** ** :*: . .:...* :: :..* * *:*::..:**** ... : * . ::: *::*:. ::* : ** * *:*: **:**.* ** . :. * .** :: *. * : : : : * .: :.: . : : :. ... * . ::** :.* * . : : *:: . *..: . * : * * *. : * . . *:: .. .. *:. ", "identical_positions": 171, "similar_positions": 279, "identity": "17.08%" }, { "cls_id": "homologset.agr.MGI:1330821", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P01619-1", "uniprot_id": "KV320_HUMAN", "id": "P01619-1", "name": "Immunoglobulin kappa variable 3-20", "aln": "ME---TPAQLLFLLLLWLPDTTGEIVLTQSPGTLSLSPGERATLSCRASQSVSSS---YLAWYQQKPGQAPRLLIYGASSRATGIPDRFSGSGSGTDFTLTISRLEPEDFAVYYCQQYGSSP------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0C4DH25-1", "uniprot_id": "KVD20_HUMAN", "id": "A0A0C4DH25-1", "name": "Immunoglobulin kappa variable 3D-20", "aln": "ME---TPAQLLFLLLLWLPDTTGEIVLTQSPATLSLSPGERATLSCGASQSVSSS---YLAWYQQKPGLAPRLLIYDASSRATGIPDRFSGSGSGTDFTLTISRLEPEDFAVYYCQQYGSSP------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P04433-1", "uniprot_id": "KV311_HUMAN", "id": "P04433-1", "name": "Immunoglobulin kappa variable 3-11", "aln": "ME---APAQLLFLLLLWLPDTTGEIVLTQSPATLSLSPGERATLSCRASQSVSS----YLAWYQQKPGQAPRLLIYDASNRATGIPARFSGSGSGTDFTLTISSLEPEDFAVYYCQQRSNWP------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0A0MRZ8-1", "uniprot_id": "KVD11_HUMAN", "id": "A0A0A0MRZ8-1", "name": "Immunoglobulin kappa variable 3D-11", "aln": "ME---APAQLLFLLLLWLPDTTGEIVLTQSPATLSLSPGERATLSCRASQSVSS----YLAWYQQKPGQAPRLLIYDASNRATGIPARFSGSGPGTDFTLTISSLEPEDFAVYYCQQRSNWH------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P01624-1", "uniprot_id": "KV315_HUMAN", "id": "P01624-1", "name": "Immunoglobulin kappa variable 3-15", "aln": "ME---APAQLLFLLLLWLPDTTGEIVMTQSPATLSVSPGERATLSCRASQSVSSN----LAWYQQKPGQAPRLLIYGASTRATGIPARFSGSGSGTEFTLTISSLQSEDFAVYYCQQYNNWP------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A087WSY6-1", "uniprot_id": "KVD15_HUMAN", "id": "A0A087WSY6-1", "name": "Immunoglobulin kappa variable 3D-15", "aln": "ME---APAQLLFLLLLWLPDTTGEIVMTQSPATLSVSPGERATLSCRASQSVSSN----LAWYQQKPGQAPRLLIYGASIRATGIPARFSGSGSGTEFTLTISILQSEDFAVYYCQQYNNWP------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A075B6H7-1", "uniprot_id": "KV37_HUMAN", "id": "A0A075B6H7-1", "name": "Probable non-functional immunoglobulin kappa variable 3-7", "aln": "ME---APAQLLFLLLLWLPDTTREIVMTQSPPTLSLSPGERVTLSCRASQSVSSS---YLTWYQQKPGQAPRLLIYGASTRATSIPARFSGSGSGTDFTLTISSLQPEDFAVYYCQQDYNLP------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0C4DH90-1", "uniprot_id": "A0A0C4DH90_HUMAN", "id": "A0A0C4DH90-1", "name": "", "aln": "ME---APAQLLFLLLLWLPDTTGEIVMTQSPATLSLSPGERATLSCRASQSVSSS---YLSWYQQKPGQAPRLLIYGASTRATGIPARFSGSGSGTDFTLTISSLQPEDFAVYYCQQDYNLP------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0C4DH55-1", "uniprot_id": "KVD07_HUMAN", "id": "A0A0C4DH55-1", "name": "Immunoglobulin kappa variable 3D-7", "aln": "MEPWKPQHSFFFLLLLWLPDTTGEIVMTQSPATLSLSPGERATLSCRASQSVSSS---YLSWYQQKPGQAPRLLIYGASTRATGIPARFSGSGSGTDFTLTISSLQPEDFAVYYCQQDYNLP------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A075B5N8-1", "uniprot_id": "A0A075B5N8_MOUSE", "id": "A0A075B5N8-1", "name": "", "aln": "ME---TDTLLLWVLLLWVPGES-NIVLTQSPASLAVSLGQRATISCRASESVDSYGNSFMHWYQQKPGQPPKLLIYLASNLESGVPARFSGSGSRTDFTLTIDPVEADDAATYYCQQNNEDP------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AKA7-1", "uniprot_id": "A0A8I6AKA7_RAT", "id": "A0A8I6AKA7-1", "name": "", "aln": "ME-----------CVFIISGSTGDIVLTQSP-ALAVSLGQRATISCRASQSVSTSSYNLMHWYQQKPGEQPKLLIYDASNLASGIPVRFSGSGSGTDFTLTINPVQADDIATYYCQQSRELPPTVVQG", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** :: :.. : :**:**** :*::* *:*.*:** **:**.: : ******* *:**** ** :.:* ******. *:*****. ::.:* *.***** . ", "identical_positions": 53, "similar_positions": 31, "identity": "41.41%" }, { "cls_id": "homologset.agr.MGI:1330823", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O95258-1", "uniprot_id": "UCP5_HUMAN", "id": "O95258-1", "name": "Brain mitochondrial carrier protein 1", "aln": "MGIFPGIILIFLRVKFATAAVIVSGHQKSTTVSHEMSGLN-WKPFVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLALYSGIAPALLRQASYGTIKIGIYQSLKRLFVER----LED--ETLLINMICGVVSGVISSTIANPTDVLKIRMQAQGSLFQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGVELPVYDITKKHLILSGMMGDTILTHFVSSFTCGLAGALASNPVDVVRTRMMNQRAIVGHVD----------LYKGTVDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLKRLQI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Z2B2-1", "uniprot_id": "UCP5_MOUSE", "id": "Q9Z2B2-1", "name": "Brain mitochondrial carrier protein 1", "aln": "MGIFPGIILIFLRVKFATAAVIVSGHQKSSTLSHEMSGLN-WKPFVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDVRFKEIKYRGMFHALFRIYKEEGILALYSGIAPALLRQASYGTIKIGIYQSLKRLFVER----LED--ETLLINMICGVVSGVISSTIANPTDVLKIRMQAQGSLFQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGVELPVYDITKKHLIVSGMLGDTILTHFVSSFTCGLAGALASNPVDVVRTRMMNQRAIVGHVD----------LYKGTLDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLKRLQI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LZW8-1", "uniprot_id": "A0ABK0LZW8_RAT", "id": "A0ABK0LZW8-1", "name": "", "aln": "-----------------------------------MSGLN-WKPFVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDVRFKEIKYRGMFHALFRIYREEGILALYSGIAPALLRQASYGTIKIGIYQSLKRLFVER----LED--ETLLINMICGVVSGVISSTIANPTDVLKIRMQAQGSLFQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGVELPVYDITKKHLIVSGMLGDTILTHFVSSFTCGLAGALASNPVDVVRTRMMNQRAIVGHVD----------LYKGTLDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLKRLQI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7K566-1", "uniprot_id": "BMCP_DROME", "id": "Q7K566-1", "name": "Mitochondrial uncoupling protein Bmcp", "aln": "-----------------------------------MGEVKDWRPFVYGGVASITAEFGTFPIDTTKTRLQIQGQKIDQSFSQLRYRGMTDAFVKISREEGLRALYSGIWPAVLRQATYGTIKFGTYYTLKKLANERGLLINEDGSERVWSNILCAAAAGAISSAIANPTDVLKVRMQVHGKGQHKGLLGCFGEIYKYEGVRGLWRGVGPTAQRAVVIASVELPVYDFCKLQLMN--AFGDHVGNHFISSFIASLGSAIASTPIDVIRTRLMNQRPVSITMNGVVTAAATPKLYSGSLDCAVQTIRNEGLPALYKGFIPTWVRMGPWNIIFFITYEQLKKY--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. :: *:******:***.*******:* ******:***.** *.:::**** .*:.:* :***: ****** **:****:*****:* * :**:* ** ** * : *::*...:*.***:*********:***.:*. : .::*.* :**: **.******* ******.::..*******: * :*: :** : .**:*** ..*..*:**.*:**:***:****.: :: **.*::* :: ::**: ****** *.*:*:***************: ", "identical_positions": 165, "similar_positions": 82, "identity": "48.25%" }, { "cls_id": "homologset.agr.MGI:1330824", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P50462-1", "uniprot_id": "CSRP3_MOUSE", "id": "P50462-1", "name": "Cysteine and glycine-rich protein 3", "aln": "----------------MPNWG--GGAKCGACEKTVY-----HAEEIQCNGRSFHKTCFHCMACRKALDS----------------------------------------------------------------TTVAAHESEIYCKVCYGRRYGP--KGIGFGQGAGCLSTDTGE-----------------------HLGLQF-----------QQSPKPARAATTS-----------------------------------------------------------------------------------------------NPSK-------FSAKFGES--------------------------------------------------------------------------EKCPRCGKSVYAAEKVMGGGKPWHKTCFRCAICGKSLESTNVTD--------------------------------------------------------------------------------------------------------KDGELYCKVCYAKNFGPTGIGFGGLTQQVEKKE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P50461-1", "uniprot_id": "CSRP3_HUMAN", "id": "P50461-1", "name": "Cysteine and glycine-rich protein 3", "aln": "----------------MPNWG--GGAKCGACEKTVY-----HAEEIQCNGRSFHKTCFHCMACRKALDS----------------------------------------------------------------TTVAAHESEIYCKVCYGRRYGP--KGIGYGQGAGCLSTDTGE-----------------------HLGLQF-----------QQSPKPARSVTTS-----------------------------------------------------------------------------------------------NPSK-------FTAKFGES--------------------------------------------------------------------------EKCPRCGKSVYAAEKVMGGGKPWHKTCFRCAICGKSLESTNVTD--------------------------------------------------------------------------------------------------------KDGELYCKVCYAKNFGPTGIGFGGLTQQVEKKE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P50463-1", "uniprot_id": "CSRP3_RAT", "id": "P50463-1", "name": "Cysteine and glycine-rich protein 3", "aln": "----------------MPNWG--GGAKCGACDKTVY-----HAEEIQCNGRSFHKTCFHCMACRKALDS----------------------------------------------------------------TTVAAHESEIYCKVCYGRKYGP--KGIGFGQGAGCLSTDTGE-----------------------HLGLQF-----------QQSPKPARAATTS-----------------------------------------------------------------------------------------------NPSK-------FSAKFGES--------------------------------------------------------------------------EKCPRCGKSVYAAEKVMGGGKPWHKTCFPCAICGKSLESTNVTD--------------------------------------------------------------------------------------------------------KDGELYCKVCYAKNFGPTGIGFGGLTHQVEKKE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F1QJC0-1", "uniprot_id": "F1QJC0_DANRE", "id": "F1QJC0-1", "name": "Cysteine and glycine-rich protein 1", "aln": "----------------MPNWG--GGAKCAACEKTVY-----HAEEIQCNSRSFHKTCFICMVCRKGLDS----------------------------------------------------------------TTVAAHESEIYCKTCYGKKYGP--KGYGYGQGAGALSSDPVN-----------------------NEELQP-----------QEPKAPRPAPANS-----------------------------------------------------------------------------------------------NSSK-------FAQKFGST--------------------------------------------------------------------------DRCPRCSKAVYAAEKIMGAGKPWHKTCFRCLLCGKSLESTTVTD--------------------------------------------------------------------------------------------------------KDGELYCKVCYAKNFGPKGRGLG-NPGMVEESV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24400-1", "uniprot_id": "MLP2_DROME", "id": "Q24400-1", "name": "Muscle LIM protein Mlp84B", "aln": "----------------MPSFQPIEAPKCPRCGKSVY-----AAEERLAGGYVFHKNCFKCGMCNKSLDS----------------------------------------------------------------TNCTEHERELYCKTCHGRKFGP--KGYGFGTGAGTLSMDNGS-----------------------QFLRENGDVPSVRNGARLEPRAIARAPEGEGCPRCGGYVYAAEQMLARGRSWHKECFKCGTCKKGLDSILC----------------------------------------------------CEAPDKNIYCKGCYAKKFGPKGYGYGQGGGALQSDCY-----------------------------------AHDDGAPQIRAAIDVDKIQARPGEGCPRCGGVVYAAEQKLSKGREWHKKCFNCKDCHKTLDSINASDGPDRDVYCRTCYGKKWGPHGYGFACGSGFLQTDGLTEDQISANRPFYNPDTTSIKARDGEGCPRCGGAVFAAEQQLSKGKVWHKKCYNCADCHRPLDSVLACDGPDGDIHCRACYGKLFGPKGFGYGHAPTLVSTSGESTIQFPDGRPLAGPKTSGGCPRCGFAVFAAEQMISKTRIWHKRCFYCSDCRKSLDSTNLNDGPDGDIYCRACYGRNFGPKGVGYGLGAGALTTF----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P35688-1", "uniprot_id": "LRG1_YEAST", "id": "P35688-1", "name": "Rho-GTPase-activating protein LRG1", "aln": "MIQNSAGYRSLNTASPMTVQVKNQKKICARCNKLVIPDSQRTKTTLKALGKYYHESCFTCQDCQKPLKPKYFPYQVDKTSESILLCQYDYFRRHNLLCHVCDTPLRGLYYTAFGYRYDEEHFSCTICATPCGVKKCFMYGNQLYCKYHFLKYFSKRCKGCEFPISDQYIEFPKGEEIHCWHPECYGIHKYWHVNLAAETVGLQYLPKLEYNPNSGDKDINPTAYELDKQMQAFNFILSKTWSVLYRFEEEAASCISDMFQYLTSNDQLKGIESTGLLVLKIDCLFRGLDTLNLSTNKSMPVNSDQECIENNAMAASKYSKFPKNLSTKIMIYLQLLRKLGTENKNETITISSFMSVITGLAHFLKLLTRFGLYTALENNKLTHSVNPLLRFLREVEKNELFENNPFQYIKTPVNATDSCAGCNKYIQEECIQFYEHR-WHIACFTCSSCHKNINPRSLTDPTFNKEKKKILCSHCSIDDPASVPG--------------------FKFVTKLAQLIFLLKIALVKSRTVMLKSKASNKVGRNSLQSTMLKEQTYIRTLNDIKRLRSRRESVRVTHNKQQARKSVILETAETDLNDPTKQGDSKNLVIQTDDPSSSQQVSTRENVFSNTKTLTLDDISRIVAAEQARELRPNAFAHFKKLKETDDETSNVVPKKSGVYYSELSTMELSMIRAISLSLLAGKQLISKTDPNYTSLVSMVFSNEKQVTGSFWNRMKIMMSMEPKKPITKTVFGAPLDVLCEKWGVDSDLGVGPVKIRIPIIIDELISSLRQMDMSVEGIFRKNGNIRRLRELTANIDSNPTEAPDFSKENAIQLSALLKKFIRELPQPILSTDLYELWIKAAKIDLEDEKQRVILLIYSLLPTYNRNLLEALLSFLHWTSSFSYIENEMGSKMDIHNLSTVITPNILYLRHKEISNDNVPDEPESGLVDSFAQNKGENYFLAIEIVDYLITHNEEMAMVPKFLMNLLKDVQLQKLDNYESINHFISTVMQSKTIDYSECDIKTPVTVKDSTTTVIQGEINK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. * * * * . . :*:.** * *.* *.. .. : ::*** . : :. ** : . :. . : : . .. *:* : *. *. : : : ** ** * * *.::. . :* . :. : * . .. :. ", "identical_positions": 30, "similar_positions": 50, "identity": "2.89%" }, { "cls_id": "homologset.agr.MGI:1330826", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O70228-1", "uniprot_id": "ATP9A_MOUSE", "id": "O70228-1", "name": "Probable phospholipid-transporting ATPase IIA", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------MTDSIPLQPVR-------HKKRVDSRPRAG--------CCEWLRCCGGGEPRPRTVWLGHPEKRDQRYPRNVINNQKYNFFTFLPGVLFSQFRYFFNFYFLLLACSQFVPEMRLGALYTYWVPLGFVLAVTIIREAVEEIRCYVRDKEMNSQVYSRLTSR---GTVKVKSSNIQVGDLILVEKNQRVPADMIFLRTSEKNGSCFLRTDQLDGETDWKLRLPVACTQRLPTAADLLQIRSYVYAEEPNIDIHNFLGTFTREDSDPPISESLSIENTLWAGTVIAS-GTVVGVVLYTGRELRSVMNTSDPRSKIGLFDLEVNCLTKILFGALVVVSLVMVALQHFAG-RWYLQIIRFLLLFSNIIPISLRVNLDMGKIVYSWVIRRDSKIPGTVVRSSTIPEQLGRISYLLTDKTGTLTQNEMVFKRLHLGTVAYGLDSMDEVQSHIFSIY-----------TQQSQDPPAQKGPTVTTKVRRTMSSRVHEAVKAIALCHNVTPVYE---------SNGVTDQAEAEKQ---------FEDSCRVYQASSPDEVALVQWTESVGLTLVGRDQ--SSMQLRTPG---DQVLNLTILQVFPFTYESKRMGIIVRDESTGEITFYMKGADVVMAGIVQYNDWLEEECGNMAREGLRVLVVAKKSLTEEQYQDFEARYVQAKLSVHDRSLKVATVIES-LEMEMELLCLTGVEDQLQADVRPTLETLRNAGIKVWMLTGDKLETATCTAKNAHLVTRNQDIHVFRLVTNRGEAHLELNAFRRKHDCALVISGDSLEVCLKYYEYEFMELACQCPAVVCCRCAPTQKAQIVRLLQERTGKLTCAVGDGGNDVSMIQESDCGVGVEGKEGKQASLAADFSITQFKHLGRLLMVHGRNSYKRSAALSQFVIHRSLCISTMQAVFSSVFYFASVPLYQGFLIIGYSTIYTMFPVFSLVLDKDVKSEVAMLYPELYKDLLKGRPLSYKTFLIWVLISIYQGSTIMYG---ALLLFESEFVHIVAISFTSLILTELLMVALTIQTWHWLMTVAELLSLACYIASLVFLHEFIDVYFIATLSFLWKVSVITLVSCLPLYVLKYLRRRFSPPSYSKLTS----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6A913-1", "uniprot_id": "A0A8I6A913_RAT", "id": "A0A8I6A913-1", "name": "Phospholipid-transporting ATPase", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------MTDSIPLQPVR-------HKKRVDSRPRAG--------CCEWLRCCGGGEPRPRTVWLGHPEKRDQRYPRNVINNQKYNFFTFLPGVLFSQFRYFFNFYFLLLACSQFVPEMRLGALYTYWVPLGFVLAVTIIREAVEEIRCYIRDKEMNSQIYSRLTSR---GTVKVKSSNIQVGDLILVEKNQRVPADMIFLRTSEKNGSCFLRTDQLDGETDWKLRLPVACTQRLPTAADLLQIRSYVYAEEPNIDIHNFLGTFTREDSDPPISESLSIENTLWAGTVIAS-GTVVGVVLYTGRELRSVMNTSDPRSKIGLFDLEVNCLTKILFGALVVVSLVMVALQHFAG-RWYLQIIRFLLLFSNIIPISLRVNLDMGKIVYSWVIRRDSKIPGTVVRSSTIPEQLGRISYLLTDKTGTLTQNEMVFKRLHLGTVAYGLDSMDEVQSHIFSIY-----------TQPSQDPPAQKGPTVTTKVRRTMSSRVHEAVKAIALCHNVTPVYE---------CNGVTDQAEAEKQ---------FEDSCRVYQASSPDEVALVQWTESVGLTLVGRDQ--SSMQLRTPG---DQILNLTILQVFPFTYESKRMGIIVRDESTGEITFYMKGADVVMAGIVQYNDWLEEECGNMAREGLRVLVVAKKSLTEEQYQDFEARYVQAKLSVHDRSLKVATVIES-LEMEMELLCLTGVEDQLQADVRPTLETLRNAGIKVWMLTGDKLETATCTAKNAHLVTRNQDIHVFRLVTNRGEAHLELNAFRRKHDCALVISGDSLEVCLKYYEYEFMELACQCPAVVCCRCAPTQKAQIVRLLQERTGKLTCAVGDGGNDVSMIQESDCGVGVEGKEGKQASLAADFSITQFKHLGRLLMVHGRNSYKRSAALSQFVIHRSLCISTMQAVFSSVFYFASVPLYQGFLIIGYSTIYTMFPVFSLVLDKDVKSEVAMLYPELYKDLLKGRPLSYKTFLIWVLISIYQGSTIMYG---ALLLFESEFVHIVAISFTSLILTELLMVALTIQTWHWLMTVAELLSLACYIASLVFLHEFIDVYFIATLSFLWKVSVITLVSCLPLYVLKYLRRRFSPPSYSKLTS----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75110-1", "uniprot_id": "ATP9A_HUMAN", "id": "O75110-1", "name": "Probable phospholipid-transporting ATPase IIA", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------MTDNIPLQPVR-------QKKRMDSRPRAG--------CCEWLRCCGGGEARPRTVWLGHPEKRDQRYPRNVINNQKYNFFTFLPGVLFNQFKYFFNLYFLLLACSQFVPEMRLGALYTYWVPLGFVLAVTVIREAVEEIRCYVRDKEVNSQVYSRLTAR---GTVKVKSSNIQVGDLIIVEKNQRVPADMIFLRTSEKNGSCFLRTDQLDGETDWKLRLPVACTQRLPTAADLLQIRSYVYAEEPNIDIHNFVGTFTREDSDPPISESLSIENTLWAGTVVAS-GTVVGVVLYTGRELRSVMNTSNPRSKIGLFDLEVNCLTKILFGALVVVSLVMVALQHFAG-RWYLQIIRFLLLFSNIIPISLRVNLDMGKIVYSWVIRRDSKIPGTVVRSSTIPEQLGRISYLLTDKTGTLTQNEMIFKRLHLGTVAYGLDSMDEVQSHIFSIY-----------TQQSQDPPAQKGPTLTTKVRRTMSSRVHEAVKAIALCHNVTPVYE---------SNGVTDQAEAEKQ---------YEDSCRVYQASSPDEVALVQWTESVGLTLVGRDQ--SSMQLRTPG---DQILNFTILQIFPFTYESKRMGIIVRDESTGEITFYMKGADVVMAGIVQYNDWLEEECGNMAREGLRVLVVAKKSLAEEQYQDFEARYVQAKLSVHDRSLKVATVIES-LEMEMELLCLTGVEDQLQADVRPTLETLRNAGIKVWMLTGDKLETATCTAKNAHLVTRNQDIHVFRLVTNRGEAHLELNAFRRKHDCALVISGDSLEVCLKYYEYEFMELACQCPAVVCCRCAPTQKAQIVRLLQERTGKLTCAVGDGGNDVSMIQESDCGVGVEGKEGKQASLAADFSITQFKHLGRLLMVHGRNSYKRSAALSQFVIHRSLCISTMQAVFSSVFYFASVPLYQGFLIIGYSTIYTMFPVFSLVLDKDVKSEVAMLYPELYKDLLKGRPLSYKTFLIWVLISIYQGSTIMYG---ALLLFESEFVHIVAISFTSLILTELLMVALTIQTWHWLMTVAELLSLACYIASLVFLHEFIDVYFIATLSFLWKVSVITLVSCLPLYVLKYLRRRFSPPSYSKLTS----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VK06-1", "uniprot_id": "Q9VK06_DROME", "id": "Q9VK06-1", "name": "Phospholipid-transporting ATPase", "aln": "MAESNVPLRDFDEESETDSETELLIRRDVPSGKQNNNNIRGRRKSSMGYSGVDAGAGSSAAGGGGSFLGNLFGSNSFGSAAGQIRYRNERSRERAKHSNGSYSSISKLAQLTHTSSGVAGAGSIGGGGGGSGSATGIKVTTGDGSVAASGGSAATGDLSNGATHSTTVIDPENGSSTVFYQHNRRKSKSRSIGNVCKLCLCSCWRKWFRPRELRARTVNLGRVN--TEKFPPNEIRNQKYNFITFLPLVLFEQFRFFLNLYFLLMALSQFIPDIRIGYPYTYWGPLGFVLMVTICREAVDDLRRHQRDHEVNSQKYKRLSSTNISGYEMVPSSKLKVGDVIIVEKNERVPADLILLRTSDRSGSVFVRTDQLDGETDWKPRLAVPYTQKLSRDSELHSIDASFYVEKPQNDIHSFIATFCMADGSE--DTGLSVENTLWANTVVAA-GTATGIVIYTGCETRSVMNNSQPRSKVGLLDMEINGLTKVLFCAVLGLSLVMMMLKGFGG-PWYRYMFRFVLLFSYIIPISLRVNLDMGKAFYSWQMQNDSNIQGTVVRSTTIPEELGRISYVLTDKTGTLTQNEMVFKKIHLGIVSHDADTFHHIGQMIQKLSGNILQQQQGSLSSSSSGGDSTKPMMFGNRMRRPEGWREWEAVRALALCHNVTPVSDDEDNRSVSTASTVTGGNNSPTKSVINIEAPGSTDTEHQYQAASPDEIALVKWTEQVGLTLIARDLNTMTLQVKTPSEDNDILLHYQILQLFPFTSESKRMGIIVRESKTGQITFYLKGADVVMSSIVQYNDWLSEESGNMAREGLRTLVVAKKVLTEEQYSDFETRYNAARLSITDRVAKVAAVTES-LERELELLCLTGVEDRLQENVRPTLELLRNAGVRVWMLTGDKLETACCIAKSSQLIGRNQGLHVLRSVKTRTDAHQELNSFRRKQGHALVISGESLEVCLQYYRPEFLELATASPAVVCCRCSPTQKAQVVALIQKHTGKRTCAVGDGGNDVSMIQQADAGVGIEGREGRQASLAGDFSIPQFSHIAKLLLIHGRRSYKRSAALSQFVIHRGLIITTLQAVFSAVFYLSSVALYQGFLMVGYSTLYTMFPVFSLVLDQDITSETAVTYPELYKDLSKGRSLSYKTFFIWVLISIYQGGVIMYG---ALILFVDEFIHIVAISFSALIMTELIMVALTVRTWHRLMVLAELFSLALYLISLAVLHEYFDWEFIWSYDFLWKVSLITLVSCLPLYIIKFLRKKCSPPSYLKLS-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40527-1", "uniprot_id": "ATC7_YEAST", "id": "P40527-1", "name": "Phospholipid-transporting ATPase NEO1", "aln": "-------------------------MPNPPSFKSHKQNLFNSNNNQHANS-VDS--------------FDLHLDDSFDAALDSLQINNNPEPLSKHNTVGDRESFEMR-----TVDDLDNFSNHSSDSHRKSSNTDTHPLMYDNRLSQDDNFKFTNIASSPPSSSNNIFSKALS------YLKVSNTKNWSKFG-----SPIELSDQHIEREIHPDTTPVYDRN----RYVSNELSNAKYNAVTFVPTLLYEQFKFFYNLYFLVVALSQAVPALRIGYLSSYIVPLAFVLTVTMAKEAIDDIQRRRRDRESNNELYHVITRN-----RSIPSKDLKVGDLIKVHKGDRIPADLVLLQSSEPSGESFIKTDQLDGETDWKLRVACPLTQNLSENDLINRIS--ITASAPEKSIHKFLGKVTYKDSTS---NPLSVDNTLWANTVLASSGFCIACVVYTGRDTRQAMNTTTAKVKTGLLELEINSISKILCACVFALSILLVAFAGFHNDDWYIDILRYLILFSTIIPVSLRVNLDLAKSVYAHQIEHDKTIPETIVRTSTIPEDLGRIEYLLSDKTGTLTQNDMQLKKIHLGTVSYTSETLDIVSDYVQSLV-------------SSKNDSLNNSKVALSTTRKDMSFRVRDMILTLAICHNVTPTFE---------------------------------DDELTYQAASPDEIAIVKFTESVGLSLFKRDRHSISLLHEHSG----KTLNYEILQVFPFNSDSKRMGIIVRDEQLDEYWFMQKGADTVMSKIVESNDWLEEETGNMAREGLRTLVIGRKKLNKKIYEQFQKEYNDASLSMLNRDQQMSQVITKYLEHDLELLGLTGVEDKLQKDVKSSIELLRNAGIKIWMLTGDKVETARCVSISAKLISRGQYVHTITKVTRPEGAFNQLEYLKINRNACLLIDGESLGMFLKHYEQEFFDVVVHLPTVIACRCTPQQKADVALVIRKMTGKRVCCIGDGGNDVSMIQCADVGVGIVGKEGKQASLAADFSITQFCHLTELLLWHGRNSYKRSAKLAQFVMHRGLIIAICQAVYSICSLFEPIALYQGWLMVGYATCYTMAPVFSLTLDHDIEESLTKIYPELYKELTEGKSLSYKTFFVWVLLSLFQGSVIQLFSQAFTSLLDTDFTRMVAISFTALVVNELIMVALEIYTWNKTMLVTEIATLLFYIVSVPFLGDYFDLGYMTTVNYYAGLLVILLISIFPVWTAKAIYRRLHPPSYAKVQEFATP", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. :. : .:: : * :. *. : : :: * : * *** .**:* :*:.**::* *:***::* ** :* :*:* :* **.*** **: :**::::: **:* *.: * :: : *..::***:* *.*.:*:***:::*::*: .*. *::*********** *:. . **.*. : * . .. *: .**.*:... *. **::*****.**:*: * . *:*** : *..**.: .: * **:::*:* ::*:* .:. :*:::: : * . ** ::*:::*** ***:*******:.* .*: :..*..* *:**::****:****.*:*:*********:* :*::*** *:: :::. : . : .: *.. : . *: . * : : ::*:******. : * ***:****:*:*::**.***:*. ** :: . .. *: ***:***. :*********:.. .: * ****.**: **: ****.** *********.**:.:* * :: *.:*: .* * **: :* ::: * . ** ::*** ******:** :*:.::* *****:::*******:*** * : .::*: *.* :*.: *. *. :*: :: ::. .*:*.*:** : *::*. **:::. *:*:.***:* ***::. :::: *** .*.:*********** :* ***: *:**:*****.****.** *: .**: ***.****** *:***:**.* *: ***:* : .:.****:*::**:* *** *****.**:*: .. : ******:* :*:.******::***:*::**..* *: :* ::*****::*::.**:**** : **: * ::*: :* *: *: .* :::* :: : .: : :* *:* :*:: * : :: **** *: ", "identical_positions": 416, "similar_positions": 337, "identity": "32.73%" }, { "cls_id": "homologset.agr.MGI:1330828", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M491-1", "uniprot_id": "F1M491_RAT", "id": "F1M491-1", "name": "", "aln": "MGTVLSLSP---------------------------------------------ASSAKGRRPGGLPEEKKKAPPAG--------------------------------DEALGGYGAPPAGKGGKG--ESRLKRPSVLISALTWKRLVAASAKKKKGSKK--------------VTPKPASTG--------------------------PDPLVQQRNRENLLRK-GRDAPDGGGAAKPLAVPVPTVPASAATCEPPSGGSAAAPPPGSGGGK-----------PPPPPPPAPQAAPPAPGGSPRRVIVQASTGELLRCLGDFVCRRCYRLKELSPGELVGWFRGVDRSLLLQGWQDQAFITPANLVFVYLLCRESLRGDELASAAELQAAFLTCLYLAYSYMGNEISYPLKPFLVEPDKERFWQRCLRLIQRLSPQMLRLNADPHFFTQVFQDLKNEGEAAVSG-FTGRGVGVGDDRGKCTPNFVHPFRLSAPPSFHFCPGLPLPCCGHLKVLHPGFCPVPHFSVSSSFLLSAVPLSLPVLWHSLGFTLFYLTPEPDGPPLLSPVLQHLYFHVPFPSSTHMSPLPSCLPSLSLLVSSCTP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35926-1", "uniprot_id": "CD5R2_MOUSE", "id": "O35926-1", "name": "Cyclin-dependent kinase 5 activator 2", "aln": "MGTVLSLSP---------------------------------------------ASSAKGRRPGGLPEEKKKAPPAG--------------------------------DEALGGYGAPPAGKGGKG--ESRLKRPSVLISALTWKRLVAASAKKKKGSKK--------------VTPKPASTG--------------------------PDPLVQQRNRENLLRK-GRDGPDGGGTAKPLAVPVPTVPTTAATCEPPSGGSAAAPPPGSGGGK-----------PPPPPPPAPQAAPPAPGGSPRRVIVQASTGELLRCLGDFVCRRCYRLKELSPGELVGWFRGVDRSLLLQGWQDQAFITPANLVFVYLLCRESLRGDELASAAELQAAFLTCLYLAYSYMGNEISYPLKPFLVEPDKERFWQRCLRLIQRLSPQMLRLNADPHFFTQVFQDLKNEGEAAAS---TG-----------------------------------------------------------------------------------------GPPSGS----------SASTTSSSSARDSCATGAKHWTMNLDR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13319-1", "uniprot_id": "CD5R2_HUMAN", "id": "Q13319-1", "name": "Cyclin-dependent kinase 5 activator 2", "aln": "MGTVLSLSP---------------------------------------------ASSAKGRRPGGLPEEKKKAPPAG--------------------------------DEALGGYGAPPVGKGGKG--ESRLKRPSVLISALTWKRLVAASAKKKKGSKK--------------VTPKPASTG--------------------------PDPLVQQRNRENLLRK-GRDPPDGGGTAKPLAVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGK-----------PPPPPPPAPQVAPPVPGGSPRRVIVQASTGELLRCLGDFVCRRCYRLKELSPGELVGWFRGVDRSLLLQGWQDQAFITPANLVFVYLLCRESLRGDELASAAELQAAFLTCLYLAYSYMGNEISYPLKPFLVEPDKERFWQRCLRLIQRLSPQMLRLNADPHFFTQVFQDLKNEGEAAASGG--------------------------------------------------------------------------------------------GPPSGG------------APAASSAARDSCAAGTKHWTMNLDR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V3H5-1", "uniprot_id": "Q9V3H5_DROME", "id": "Q9V3H5-1", "name": "Cyclin-dependent kinase 5 activator", "aln": "MGTVLSFNPRDRHPIYSSQPNFQYNHSTDMRNENDSTGSIDSHLNNFSYEQLNNAKNRENKKSACHPMAKNVIGQPGGQCGGVHINLQTQTQLSSHNLNNLANASKDTITNVLDTHNENSVLKAEKSSFEKNLKKHSIFINALSWKKLSTSHNKKKIENKNKCANLPTACFKAQLLESSFASSSDKNRNIQLHCNRIDEHNQQHCNQHPHPHPHQHQLQLQNQHQHQNQNQNQNQNQVQDIREEVMTGPPGKSQNPSKAKDPVKVNNKNSMSNHNKLIQKQPLTLSLPQQVQASSIQTKNTNQIPRKTVIQASTSELLKCLGMFLHCRCQRLNNFDAGDAVMWLRAVDRSLLLQGWQDVAFINPANVVFVYMLVRELVSGEESK-ESDLQASVLTCLYLSYSYMGNEISYPLKPFLVEDSKEKFWDRCLVIVNKLSDKMLKINAEPGFFTEVFTELKSCG-----------------------------------------------------------------------------------------------------------------------QYHPTIKSYCGGA----------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******:.* *.. :.::.. * *: .* :.*. :. .. *. *. *..**: *::*.**:**:* :: *** .*: : .. **:. *.* :* : :* :: .:: :. . .: : * * *. : . : ... . .* ..: . * *.. . .. **:.::****.***:*** *: ** **:::..*: * *:*.************ ***.***:****:* ** : *:* ::***:.******:****************** .**:**:*** ::::** :**::**:* ***:** :**. * : * . ", "identical_positions": 138, "similar_positions": 112, "identity": "22.92%" }, { "cls_id": "homologset.agr.MGI:1330829", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P06312-1", "uniprot_id": "KV401_HUMAN", "id": "P06312-1", "name": "Immunoglobulin kappa variable 4-1", "aln": "MVLQTQVFISLLLWISGAYGDIVMTQSPDSLAVSLGERATINCKSSQSVLYSSNNKNYLAWYQQKPGQPPKLLIYWASTRESGVPDRFSGSGSGTDFTLTISSLQAEDVAVYYCQQYYSTP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A075B5N7-1", "uniprot_id": "A0A075B5N7_MOUSE", "id": "A0A075B5N7-1", "name": "", "aln": "--------------------DIVMTQSQKFMSTSVGDRVSITCKASQNVG------TAVAWYQQKPGQSPKLLIYSASNRYTGVPDRFTGSGSGTDFTLTISNMQSEDLADYFCQQYSSYP", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ******* . ::.*:*:*.:*.**:**.* . :*********.****** **.* :******:*************.:*:**:* *:**** * *", "identical_positions": 64, "similar_positions": 22, "identity": "52.89%" }, { "cls_id": "homologset.agr.MGI:1330830", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P06312-1", "uniprot_id": "KV401_HUMAN", "id": "P06312-1", "name": "Immunoglobulin kappa variable 4-1", "aln": "MVLQTQVFISLLLWISGAYGDIVMTQSPDSLAVSLGERATINCKSSQSVLYSSNNKNYLAWYQQKPGQPPKLLIYWASTRESGVPDRFSGSGSGTDFTLTISSLQAEDVAVYYCQQYYSTP--------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A140T8P1-1", "uniprot_id": "A0A140T8P1_MOUSE", "id": "A0A140T8P1-1", "name": "", "aln": "MEFQTQVFVFVLLWLSGVDGDIVMTQSQKFMSTSVGDRVSITCKASQ------NVRTAVAWYQQKPGQSPKALIYLASNRHTGVPDRFTGSGSGTDFTLTISNVQSEDLADYFCLQHWNYP--------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1M3Y4-1", "uniprot_id": "F1M3Y4_RAT", "id": "F1M3Y4-1", "name": "", "aln": "--------------------DTVMTQSPASMSTSVGERVTVNCKASQ------SVGTVVAWFQQKPGQSPKRLIYLATNRHTGVPDRFTGSGFGRDFTLTISNVEAEDLAVYYCLQYDSIPPTVFQPHTETSSAILTSCMHHTALDLHTFLLPTTAMPN", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * ***** ::.*:*:*.::.**:** . . :**:******.** *** *:.*.:******:*** * *******.:::**:* *:* *: . * ", "identical_positions": 52, "similar_positions": 28, "identity": "32.7%" }, { "cls_id": "homologset.agr.MGI:1330831", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P06312-1", "uniprot_id": "KV401_HUMAN", "id": "P06312-1", "name": "Immunoglobulin kappa variable 4-1", "aln": "MVLQTQVFISLLLWISGAYGDIVMTQSPDSLAVSLGERATINCKSSQSVLYSSNNKNYLAWYQQKPGQPPKLLIYWASTRESGVPDRFSGSGSGTDFTLTISSLQAEDVAVYYCQQYYSTP--------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A140T8M5-1", "uniprot_id": "A0A140T8M5_MOUSE", "id": "A0A140T8M5-1", "name": "", "aln": "MESQTQVFVYMLLWLSGVDGDIVMTQSQKFMSTSVGDRVSVTCKASQNVG--TN----VAWYQQKPGQSPKALIYSASYRYSGVPDRFTGSGSGTDFTLTISNVQSEDLAEYFCQQYNSYP--------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1M3Y4-1", "uniprot_id": "F1M3Y4_RAT", "id": "F1M3Y4-1", "name": "", "aln": "--------------------DTVMTQSPASMSTSVGERVTVNCKASQSVG------TVVAWFQQKPGQSPKRLIYLATNRHTGVPDRFTGSGFGRDFTLTISNVEAEDLAVYYCLQYDSIPPTVFQPHTETSSAILTSCMHHTALDLHTFLLPTTAMPN", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * ***** ::.*:*:*.::.**:**.* :**:******.** *** *: * :******:*** * *******.:::**:* *:* ** * * ", "identical_positions": 55, "similar_positions": 23, "identity": "34.59%" }, { "cls_id": "homologset.agr.MGI:1330832", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JJS8-1", "uniprot_id": "MASP2_RAT", "id": "Q9JJS8-1", "name": "Mannan-binding lectin serine protease 2", "aln": "-MRLLIVLGLLWSLVATLLGSKWPEPVFGRLVSLGFPEKYGNHQDRSWTLTAPPGFRLRLYFTHFNLELSYRCEYDFVKLTSGTKVLATLCGQESTDTERAPGNDTFYSLGPSLKVTFHSDYSNEKPFTGFEAFYAAEDVDECRTSLGDSVPCDHYCHNYLGGYYCSCRVGYILHQNKHTCSALCSGQVFTGRSGFLSSPEYPQPYPKLSSCAYNIRLEEGFSITLDFVESFDVEMHPEAQCPYDSLKIQTDKREYGPFCGKTLPPRIETDSNKVTITFTTDESGNHTGWKIHYTSTAQPCPDPTAPPNGHISPVQATYVLKDSFSVFCKTGFELLQGSVPLKSFTAVCQKDGSWDRPIPECSIIDCGPPDDLPNGHVDYITGPEVTTYKAVIQYSCEETFYTMSSN--GKYVCEADGFWTSSKGEKSLPVCKPVCGLSTHTSGGRIIGGQPAKPGDFPWQVLL-LGETTAAG-ALIHDDWVLTAAHAVYGKTEAMSSLDIRMGILKRLSLIYTQAWPEAVFIHEGYTHG-AGFDNDIALIKLKNKVTINRNIMPICLPRKEAASLMKTDFVGTVAGWGLT---QKGFLARNLMFVDIPIVDHQKCATAYTKQPYPGAK--VTVNMLCAGLDRGGKDSCRGDSGGALVFLDNETQRWFVGGIVSWGSINCGGSEQYGVYTKVTNYIPWIENIINNF-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91WP0-1", "uniprot_id": "MASP2_MOUSE", "id": "Q91WP0-1", "name": "Mannan-binding lectin serine protease 2", "aln": "-MRLLIFLGLLWSLVATLLGSKWPEPVFGRLVSPGFPEKYADHQDRSWTLTAPPGYRLRLYFTHFDLELSYRCEYDFVKLSSGTKVLATLCGQESTDTEQAPGNDTFYSLGPSLKVTFHSDYSNEKPFTGFEAFYAAEDVDECRVSLGDSVPCDHYCHNYLGGYYCSCRAGYVLHQNKHTCSALCSGQVFTGRSGYLSSPEYPQPYPKLSSCTYSIRLEDGFSVILDFVESFDVETHPEAQCPYDSLKIQTDKGEHGPFCGKTLPPRIETDSHKVTITFATDESGNHTGWKIHYTSTARPCPDPTAPPNGSISPVQAIYVLKDRFSVFCKTGFELLQGSVPLKSFTAVCQKDGSWDRPMPECSIIDCGPPDDLPNGHVDYITGPEVTTYKAVIQYSCEETFYTMSSN--GKYVCEADGFWTSSKGEKLPPVCEPVCGLSTHTIGGRIVGGQPAKPGDFPWQVLL-LGQTTAAAGALIHDNWVLTAAHAVYEKRMAASSLNIRMGILKRLSPHYTQAWPEEIFIHEGYTHG-AGFDNDIALIKLKNKVTINGSIMPVCLPRKEAASLMRTDFTGTVAGWGLT---QKGLLARNLMFVDIPIADHQKCTAVYEKL-YPGVR--VSANMLCAGLETGGKDSCRGDSGGALVFLDNETQRWFVGGIVSWGSINCGAADQYGVYTKVINYIPWIENIISNF-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00187-1", "uniprot_id": "MASP2_HUMAN", "id": "O00187-1", "name": "Mannan-binding lectin serine protease 2", "aln": "-MRLLTLLGLLCGSVATPLGPKWPEPVFGRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVLATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDECQVAPGEAPTCDHHCHNHLGGFYCSCRAGYVLHRNKRTCSALCSGQVFTQRSGELSSPEYPRPYPKLSSCTYSISLEEGFSVILDFVESFDVETHPETLCPYDFLKIQTDREEHGPFCGKTLPHRIETKSNTVTITFVTDESGDHTGWKIHYTSTAQPCPYPMAPPNGHVSPVQAKYILKDSFSIFCETGYELLQGHLPLKSFTAVCQKDGSWDRPMPACSIVDCGPPDDLPSGRVEYITGPGVTTYKAVIQYSCEETFYTMKVND-GKYVCEADGFWTSSKGEKSLPVCEPVCGLSARTTGGRIYGGQKAKPGDFPWQVLI-LGGTTAAG-ALLYDNWVLTAAHAVYEQKHDASALDIRMGTLKRLSPHYTQAWSEAVFIHEGYTHD-AGFDNDIALIKLNNKVVINSNITPICLPRKEAESFMRTDDIGTASGWGLT---QRGFLARNLMYVDIPIVDHQKCTAAYEKPPYPRGS--VTANMLCAGLESGGKDSCRGDSGGALVFLDSETERWFVGGIVSWGSMNCGEAGQYGVYTKVINYIPWIENIISDF-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NGF4-1", "uniprot_id": "A0A8M1NGF4_DANRE", "id": "A0A8M1NGF4-1", "name": "", "aln": "MNSVLAFIALLPLAFGLELTG-----LFGSFTSPNFPNVYPNNQRVVWNITAPEGHRVRLYFTYFSLEPSHRCEYDYVQVFSEGNETVRFCGDTEKNYGDAPKNTVIYSATSSMSVVFRSDYSNEDRFTGFQAFFSAEDIDECLSSVDGEPVCDHNCHNYVGGFYCTCRLGYQLHADKRHCPVECSGQVFQQRSGELSSPEYPGVYPKMSRCDYTISLMEGFQVTLDFQDLFDVETHPEIQCPYDILKITAGGREYGPFCGKTPPRKIETGTHKVHVTFRSDRSGKNKGWKIKYTSTAQPCPNPVAPQQGHIEPQQPQYIMTDTFNVTCDLGYEIILGEEALPFYQATCLRGGFWNGPMPNCVIVDCGEPPEVCNATVKYTT----TIYKSVIKYTCNE-FYSMDVGASGVYTCAHDGYWRDALGGKIQQICLPICGQPELKLS-KVIGGENAEKNEIPWQVMIRMGTKFIGGASLLSDGWVLTAAHVVKSFEDSAN-LQLRMGTVKHHDNEAVVGIPQKIFIHPQYHHDNVNFNHDIALIKLEYKVPVSKAVMPVCLPGREERFVLKANDVGKVSGWGVSNINTPALFSGNLKYVHLPVSNFNDCKTKYDSTVTSKGKLVVTENMICAGFSQGGKDSCQGDSGGPFAFFDKQSKSWFIGGIVSWG-HGCAQAGYYGVYTKVSNYLSWIEEVMSKNS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* .:.** .. * :** :.* .** * :.* *.:*** *.*:*****:*.** *: ****:*:: * : . :**: ..: ** : .:** .*:.:.*:******. ****:**::***:*** : . *** ***::**:**:** ** ** :*: *.. ****** *** ******* ***:* * *.* * :**.: *** : **** *** **** *** :. *:******* * :*** ::.* :** :*.**.:.****:*****:*** * ** :* :.* *. *::.* *.: *. *:*:: * .* : *.* :.* *: *:* * *:*** * :: .. *.* * * **:**:*:*:* **:*. . * *.* **:* .: * * :* *:** . . . :: **: *: .::****:: :* . .. :*: *.*******.* . *::*** :*: . . . .: :*** * *. ..*::*******: ** :. : *:*** :* .:::: *..:***:: .::: ** :*.:*: :.:.* : * . . *: **:***:. ******:*****.:.*:*.::: **:******* .*. : ******* **:.***:::.. ", "identical_positions": 295, "similar_positions": 204, "identity": "42.32%" }, { "cls_id": "homologset.agr.MGI:1330833", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P06312-1", "uniprot_id": "KV401_HUMAN", "id": "P06312-1", "name": "Immunoglobulin kappa variable 4-1", "aln": "---------MVLQTQVFISLLLWIS------------GAYGDIVMTQSPDSLAVSLGERATINCKSSQSVLYSSNNKNYLAWYQQKPGQPPKLLIYWASTRESGVPDRFSGSGSGTDFTLTISSLQAEDVAVYYCQQYYSTP--------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P01633-1", "uniprot_id": "KV5A1_MOUSE", "id": "P01633-1", "name": "Immunoglobulin kappa chain variable 6-17", "aln": "MHHTSMGIKMESQIQVFVFVFLWLSGVDGDIVMTQFAGVDGDIVMTQSHKFMSTSVGDRVSITCKASQDVSTT------VAWYQQKPGQSPKLLIYSASYRYTGVPDRFTGSGSGTDFTFTISSVQAEDLAVYYCQQHYSTPPTFGG---------------GTKLEIKR----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1M3Y4-1", "uniprot_id": "F1M3Y4_RAT", "id": "F1M3Y4-1", "name": "", "aln": "-----------------------------------------DTVMTQSPASMSTSVGERVTVNCKASQSVGTV------VAWFQQKPGQSPKRLIYLATNRHTGVPDRFTGSGFGRDFTLTISNVEAEDLAVYYCLQYDSIPPTVFQPHTETSSAILTSCMHHTALDLHTFLLPTTAMPN", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * ***** ::.*:*:*.::.**:**.* :**:******.** *** *: * :******:*** * ***:***.::***:***** *: * * ", "identical_positions": 56, "similar_positions": 23, "identity": "31.11%" }, { "cls_id": "homologset.agr.MGI:1330836", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P06312-1", "uniprot_id": "KV401_HUMAN", "id": "P06312-1", "name": "Immunoglobulin kappa variable 4-1", "aln": "MVLQTQVFISLLLWISGAYGDIVMTQSPDSLAVSLGERATINCKSSQSVLYSSNNKNYLAWYQQKPGQPPKLLIYWASTRESGVPDRFSGSGSGTDFTLTISSLQAEDVAVYYCQQYYSTP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A140T8P2-1", "uniprot_id": "A0A140T8P2_MOUSE", "id": "A0A140T8P2-1", "name": "", "aln": "MESQTLVFISILLWLYGADGNIVMTQSPKSMSMSVGERVTLSCKASENVG------TYVSWYQQKPEQSPKLLIYGASNRYTGVPDRFTGSGSATDFTLTISSVQAEDLADYHCGQSYSYP", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* ** ****:***: ** *:*******.*:::*:***.*:.**:*:.* .*::****** *.****** **.* :******:****.*********:****:* *:* * ** *", "identical_positions": 77, "similar_positions": 25, "identity": "63.64%" }, { "cls_id": "homologset.agr.MGI:1330838", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O89017-1", "uniprot_id": "LGMN_MOUSE", "id": "O89017-1", "name": "Legumain", "aln": "MTWRVAVLLSLVLGAGAVPVGVDDPEDGGKHWVVIVAGSNGWYNYRHQADACHAYQIIHRNGIPDEQIIVMMYDDIANSEENPTPGVVINRPNGTDVYKGVLKDYTGEDVTPENFLAVLRGDAEAVKGKGSGKVLKSGPRDHVFIYFTDHGATGILVFPNDDLHVKDLNKTIRYMYEHKMYQKMVFYIEACESGSMMNHLPDDINVYATTAANPKESSYACYYDEERGTYLGDWYSVNWMEDSDVEDLTKETLHKQYHLVKSHTNTSHVMQYGNKSISTMKVMQFQGMKHRASSPISLPPVTHLDLTPSPDVPLTILKRKLLRTNDVKESQNLIGQIQQFLDARHVIEKSVHKIVSLLAGFGETAERHLSERTMLTAHDCYQEAVTHFRTHCFNWHSVTYEHALRYLYVLANLCEAPYPIDRIEMAMDKVCLSHY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9R0J8-1", "uniprot_id": "LGMN_RAT", "id": "Q9R0J8-1", "name": "Legumain", "aln": "MTWRVAVLLSLVLGAGAVHIGVDDPEDGGKHWVVIVAGSNGWYNYRHQADACHAYQIIHRNGIPDEQIIVMMYDDIANNEENPTPGVVINRPNGTDVYKGVPKDYTGEDVTPENFLAVLRGDEEAVKGKGSGKVLKSGPRDHVFVYFTDHGATGILVFPNEDLHVKDLNKTIRYMYEHKMYQKMVFYIEACESGSMMNHLPDDIDVYATTAANPNESSYACYYDEERSTYLGDWYSVNWMEDSDVEDLTKETLHKQYHLVKSHTNTSHVMQYGNKSISTMKVMQFQGMKHRASSPISLPPVTHLDLTPSPDVPLTILKRKLLRTNNMKESQVLVGQIQHLLDARHIIEKSVQKIVSLLAGFGETAQKHLSERAMLTAHDCHQEAVTHFRTHCFNWHSVTYEHALRYLYVLANLCEKPYPIDRIKMAMDKVCLSHY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99538-1", "uniprot_id": "LGMN_HUMAN", "id": "Q99538-1", "name": "Legumain", "aln": "MVWKVAVFLSVALGIGAVPI--DDPEDGGKHWVVIVAGSNGWYNYRHQADACHAYQIIHRNGIPDEQIVVMMYDDIAYSEDNPTPGIVINRPNGTDVYQGVPKDYTGEDVTPQNFLAVLRGDAEAVKGIGSGKVLKSGPQDHVFIYFTDHGSTGILVFPNEDLHVKDLNETIHYMYKHKMYRKMVFYIEACESGSMMNHLPDNINVYATTAANPRESSYACYYDEKRSTYLGDWYSVNWMEDSDVEDLTKETLHKQYHLVKSHTNTSHVMQYGNKTISTMKVMQFQGMKRKASSPVPLPPVTHLDLTPSPDVPLTIMKRKLMNTNDLEESRQLTEEIQRHLDARHLIEKSVRKIVSLLAASEAEVEQLLSERAPLTGHSCYPEALLHFRTHCFNWHSPTYEYALRHLYVLVNLCEKPYPLHRIKLSMDHVCLGHY", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.*:***:**:.** *** : **********************************************:******** .*:*****:***********:** **********:********* ***** **********:****:******:********:********:**:***:****:********************:*:*********.**********:*.***********************************************:*************::****:.*******************:****:.**:::**: * :**: *****:*****:*******. .:: ****: **.*.*: **: *********** ***:***:****.**** ***:.**:::**:***.**", "identical_positions": 353, "similar_positions": 60, "identity": "81.15%" }, { "cls_id": "homologset.agr.MGI:1330839", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q792I0-1", "uniprot_id": "LIN7C_RAT", "id": "Q792I0-1", "name": "Protein lin-7 homolog C", "aln": "MAALGEPVRLERDICRAIELLEKLQRSGEVPPQKLQALQRVLQSEFCNAVREVYEHVYETVDISSSPEVRANATAKATVAAFAASEGHSHPRVVELPKTEEG---------------------------------------------------LGFNIMGGKEQNSPIYISRIIPGGIADRHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAQGKVKLVVRYTPKVLEEMESRFEKMRSAKRRQQT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88952-1", "uniprot_id": "LIN7C_MOUSE", "id": "O88952-1", "name": "Protein lin-7 homolog C", "aln": "MAALGEPVRLERDICRAIELLEKLQRSGEVPPQKLQALQRVLQSEFCNAVREVYEHVYETVDISSSPEVRANATAKATVAAFAASEGHSHPRVVELPKTEEG---------------------------------------------------LGFNIMGGKEQNSPIYISRIIPGGIADRHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAQGKVKLVVRYTPKVLEEMESRFEKMRSAKRRQQT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NUP9-1", "uniprot_id": "LIN7C_HUMAN", "id": "Q9NUP9-1", "name": "Protein lin-7 homolog C", "aln": "MAALGEPVRLERDICRAIELLEKLQRSGEVPPQKLQALQRVLQSEFCNAVREVYEHVYETVDISSSPEVRANATAKATVAAFAASEGHSHPRVVELPKTEEG---------------------------------------------------LGFNIMGGKEQNSPIYISRIIPGGIADRHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAQGKVKLVVRYTPKVLEEMESRFEKMRSAKRRQQT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8IMT8-1", "uniprot_id": "Q8IMT8_DROME", "id": "Q8IMT8-1", "name": "Protein lin-7 homolog", "aln": "MADNAEPLTLSRDVKRSIELLEKLQASGDFPTTKLAALQKVLNSDFMTSVREVYEHVYETVDIQGSHDVRASATAKATVAAFAASEGHAHPRVVELPKTEEGKTRPYELRIEGIPLYHKTNTLIVKVYRPRIYVSIIHLIWKALSIFNFCFSGLGFNVMGGKEQNSPIYISRIIPGGVADRHGGLKRGDQLLSVNGVSVEGENHEKAVELLKQAVGSVKLVVRYTPKVLEEMEMRFDKQRNTRRRQ--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** .**: *.**: *:******** **:.*. ** ***:**:*:* .:**************..* :***.****************:************* ****:*******************:************************:********* * *.**************** **:* *.::*** ", "identical_positions": 156, "similar_positions": 26, "identity": "62.9%" }, { "cls_id": "homologset.agr.MGI:1330840", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P06312-1", "uniprot_id": "KV401_HUMAN", "id": "P06312-1", "name": "Immunoglobulin kappa variable 4-1", "aln": "MVLQTQVFISLLLWISGAYGDIVMTQSPDSLAVSLGERATINCKSSQSVLYSSNNKNYLAWYQQKPGQPPKLLIYWASTRESGVPDRFSGSGSGTDFTLTISSLQAEDVAVYYCQQYYSTP-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A140T8P7-1", "uniprot_id": "A0A140T8P7_MOUSE", "id": "A0A140T8P7-1", "name": "", "aln": "MDSQAQVLILLLLWVSGTCGDIVMSQSPSSLAVSAGEKVTMSCKSSQSLLNSRTRKNYLAWYQQKPGQSPKLLIYWASTRESGVPDRFTGSGSGTDFTLTISSVQAEDLAVYYCKQSYNL------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZLJ1-1", "uniprot_id": "A0A8I5ZLJ1_RAT", "id": "A0A8I5ZLJ1-1", "name": "Ig-like domain-containing protein", "aln": "------MHVHRPFVTVGTCGDIVMTQSPSSLAVSAGEKVTMRCKTSQSLLLTSNQKNYLAWYQQKPWQSSKLLISWASPEKSGVPDRFTGSGSGTDFTLTISSVQAEDMAVYYCYQYYNYPPTVIQPPTQTS", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : *: *****:***.***** **:.*: **:***:* : ..*********** *..**** ***..:*******:**************:****:***** * *. ", "identical_positions": 74, "similar_positions": 23, "identity": "56.06%" }, { "cls_id": "homologset.agr.MGI:1330841", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99M66-1", "uniprot_id": "B2L10_RAT", "id": "Q99M66-1", "name": "Bcl-2-like protein 10", "aln": "-----------------MG----------DPLQDRTRRLLTDYILFCARAPNTPEPLPTSVEAALLRSVTSQIQQEHQDLFNSFRDYQGNRLELVTQMADELLSNDQEFNWGRLVMLLAFVGTLMNQD--RTVKRRR-DQRNRLL-----LERDCYLIVSLLYNRLTG-RHRSWLEAHGGWDGFCQFFKNPLPPGFWRRLLIRAILSCFFATA-IFYIWKCL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z0F3-1", "uniprot_id": "B2L10_MOUSE", "id": "Q9Z0F3-1", "name": "Bcl-2-like protein 10", "aln": "-----------------MADSQ-------DPLHERTRRLLSDYIFFCAREPDTPEPPPTSVEAALLRSVTRQIQQEHQEFFSSFCESRGNRLELVKQMADKLLSKDQDFSWSQLVMLLAFAGTLMNQGPYMAVKQKR-DLGNRVI-----VTRDCCLIVNFLYNLLMGRRHRARLEALGGWDGFCRFFKNPLPLGFWRRLLIQAFLSGFFATA-IFFIWKRL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HD36-1", "uniprot_id": "B2L10_HUMAN", "id": "Q9HD36-1", "name": "Bcl-2-like protein 10", "aln": "-----------------MVDQLRERTTMADPLRERTELLLADYLGYCAREPGTPEPAPSTPEAAVLRSAAARLRQIHRSFFSAYLGYPGNRFELVALMADSVLSDSPGPTWGRVVTLVTFAGTLLERGPLVTARWKKWGFQPRLKEQEGDVARDCQRLVALLSSRLMG-QHRAWLQAQGGWDGFCHFFRTPFPLAFWRKQLVQAFLSCLLTTA-FIYLWTRLL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1P8W8-1", "uniprot_id": "A0A8M1P8W8_DANRE", "id": "A0A8M1P8W8-1", "name": "", "aln": "MKIVSYEISPLFAQLSWRAQSDIAGRKMSCWLREQTLLLAEDYISFCSGIQQTPPSESAEAMRYLAKEMEQQHRTKFRSLSQEFLDTCGADPSKCLQSVMRELVGDGKMNWGRVVSIFTFTGVLASELLSRGENSEG-----------------SRRLAETIADYLGG-EKQDWLVENGGWEGFCRFFHNARQLNQESSMKTALFAAAGVGLAGLTFLLVR--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:::* * **: :*: ** . .: : :. : : .:.: . : * . . * . .*.::* :.:*.*.* .. . . . :. : . * * .:: * ***:***:**:.. : : . * : :: ", "identical_positions": 27, "similar_positions": 55, "identity": "12.11%" }, { "cls_id": "homologset.agr.MGI:1330842", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z268-1", "uniprot_id": "RASL1_MOUSE", "id": "Q9Z268-1", "name": "RasGAP-activating-like protein 1", "aln": "MAKSGSLSIRVVEGRALPAKDVSGSSDPYCLVKVDDQVVARTATIWRSLSPFWGEEYTVHLPLDFHHLAFYVLDEDTVGHDDIIGKISLSKEAITADPRGIDSWINLSRVDPDAEVQGEVCLDVKLLEDARGRCLRCHVRQARDLAPRDISGTSDPFARVFWGNHSLETSTIKKTRFPHWDEVLELREAPGTTSPLRVELWDWDMVGKNDFLGMVEFTPQTLQQKPPNGWFRLLPFPRAE-DSGGSLGALRLKVRLTEDRVLPSQYYQPLMELLLESVQGPAEEDTTSPLALLEELASGDCRQDLATKLVKLFLGRGLAGPFLDYLTRREVARTNDPNTLFRSNSLASKSMEQFMKLVGMRYLHEVLRPVISRVFEEKKYMELDPCKMDLNRSRRISFKGTPTEEQVRETSLGLLTGYLGSVVDAIVSSTGRCPLALRLAFKQLQRCVEKRFSGIEHQDVKYLAISGFLFLRFFAPAILTPKLFDLRDQHADPQTSRSLLLLAKAVQSIGNLGQQLGQGKEQWLAPLHPFLLQSISRVRDFLDQLVDVDEDEEAGGPACALVQPSTIVREGFLLKRKEEPGGLATRFAFKKRYFRLSGRDLSYSKTPEWQVHTSIPLSCIRAVEHVDEGAFQLPHVMQVVTQDGAGTSHTTYLQCKNVNDLNQWLSALRKASAPNPGKLVACHPGAFRSGRWTCCLQAERSAAGCSRTHSAITLGDWSDPLDPDAEAQAVYRQLLLGRDQLRLKLLEDSSLDT--EVDPGRDSSATDGPCAEVLAQQRAATTHLLQVLEDLEQAHEEFQK--RG---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZHY9-1", "uniprot_id": "D3ZHY9_RAT", "id": "D3ZHY9-1", "name": "", "aln": "MAKSGSLSIRVVEGRALPAKDVSGSSDPYCLVKVDDEVVARTATIWRSLSPFWGEEYTVHLPLDFHHLAFYVLDEDTVGHDDIIGKISLSKEAITADPRGIDSWINLSRVDPDEEVQGEVCLAVKLLEDARGRCLRCHVRQARDLAPRDISGTSDPFARVFWGSRSLETSTIKKTRFPHWDEVLELREAPGTTSPLRVELWDWDMVGKNDFLGMVEFTPQTLQQKPPNGWFRLLPFPRAE-DSGGSLGALRLKVRLTEDRVLPSQYYQPLMELLLESVQGPAEEDTTSPLALLEELASGDCRQDLATKLVKLFLGRGLAGPFLDYLTRREVARTNDPNTLFRSNSLASKSMEQFMKLVGMRYLHEVLRPVISRVFEEKKYMELDPSKMDLNRSRRISFKGTPTEEQVRETSLGLLTGYLGSVVDAIVSSAGRCPLALRLAFKQLQQCVEKRFPGMEHQDVKYLATSGFLFLRFFAPAILTPKLFDLRDHHADPQTSRSLLLLAKAVQSIGNLGQQLGQGKEQWLAPLHPFLLQSISRVRDFLDQLVDVDGDEEAGGSTCALVQPSTIVREGFLLKRKEEPASLATRFAFKKRYFRLSGRDLSYSKTPEWQVHSSIPLSCIRAVERVDEGAFQLPHVMQVVTQDGTGASHTTYLQCKNVNDLNQWLSALRKASAPNPGKLAACHPGAFRSGRWTCCLQAERSAVGCSRTHSAVTLGDWSDPLDPDAEAQMVYRQLLLGRDQLRLKLLEDSSLDTAPDVDPGKDSSAVDGPCAEVLAQQREATTRLLQVLEDLEQAHEEFQK--RG---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O95294-1", "uniprot_id": "RASL1_HUMAN", "id": "O95294-1", "name": "RasGAP-activating-like protein 1", "aln": "MAKSSSLNVRVVEGRALPAKDVSGSSDPYCLVKVDDEVVARTATVWRSLGPFWGEEYTVHLPLDFHQLAFYVLDEDTVGHDDIIGKISLSREAITADPRGIDSWINLSRVDPDAEVQGEICLSVQMLEDGQGRCLRCHVLQARDLAPRDISGTSDPFARVFWGSQSLETSTIKKTRFPHWDEVLELREMPGAPSPLRVELWDWDMVGKNDFLGMVEFSPKTLQQKPPKGWFRLLPFPRAEEDSGGNLGALRVKVRLIEDRVLPSQCYQPLMELLMESVQGPAEEDTASPLALLEELTLGDCRQDLATKLVKLFLGRGLAGRFLDYLTRREVARTMDPNTLFRSNSLASKSMEQFMKLVGMPYLHEVLKPVISRVFEEKKYMELDPCKMDLGRTRRISFKGALSEEQMRETSLGLLTGYLGPIVDAIVGSVGRCPPAMRLAFKQLHRRVEERFPQAEHQDVKYLAISGFLFLRFFAPAILTPKLFDLRDQHADPQTSRSLLLLAKAVQSIGNLGQQLGQGKELWMAPLHPFLLQCVSRVRDFLDRLVDVDGDE-AGVPARALFPPSAIVREGYLLKRKEEPAGLATRFAFKKRYVWLSGETLSFSKSPEWQMCHSIPVSHIRAVERVDEGAFQLPHVMQVVTQDGTGALHTTYLQCKNVNELNQWLSALRKASAPNPNKLAACHPGAFRSARWTCCLQAERSAAGCSRTHSAVTLGDWSDPLDPDAEAQTVYRQLLLGRDQLRLKLLEDSNMDTTLEADTG--------ACPEVLARQRAATARLLEVLADLDRAHEEFQQQERGKAALGPLGP", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****.**.:***************************:*******:****.****************:***********************:********************** *****:** *::***.:******** ***********************.:*********************** **:.************************:*:*******:************ ****.*****:**** ******** ********:***********:*********: ********************** ************* ************************* ******:*****************.****.*:*******: :***:*************.:*****.*.**** *:*******:: **:**. ********* ***********************:******************************** *:*********.:********:***** ** ** .: **. **:*****:********..***********. ***. **:**:****: ***:* *****:*******************:*: ***********:****************.**.*********.************.********:**************** ********************.:** :.*.* .*.****:** **::**:** **::******: ** ", "identical_positions": 678, "similar_positions": 82, "identity": "83.39%" }, { "cls_id": "homologset.agr.MGI:1330843", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P06312-1", "uniprot_id": "KV401_HUMAN", "id": "P06312-1", "name": "Immunoglobulin kappa variable 4-1", "aln": "MVLQTQVFISLLLWISGAYGDIVMTQSPDSLAVSLGERATINCKSSQSVLYSSNNKNYLAWYQQKPGQPPKLLIYWASTRESGVPDRFSGSGSGTDFTLTISSLQAEDVAVYYCQQYYSTP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0G2JDG9-1", "uniprot_id": "A0A0G2JDG9_MOUSE", "id": "A0A0G2JDG9-1", "name": "", "aln": "MVSETHVLIFLLLWVSGACGEIVLTQSIPSLTVSAGERVTISCKSNQNLLWSGNQRYCLVWHQWKPGQTPTPLITWTSDRYSGVPDRFIGSGSVTDFTLTISSVQAEDVAVYFCQQHLHIP", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** :*:*:* ****:*** *:**:*** **:** ***.**.***.*.:*:*.*:: *.*:* ****.*. ** *:* * ******* **** *********:********:***: *", "identical_positions": 79, "similar_positions": 24, "identity": "65.29%" }, { "cls_id": "homologset.agr.MGI:1330844", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P06312-1", "uniprot_id": "KV401_HUMAN", "id": "P06312-1", "name": "Immunoglobulin kappa variable 4-1", "aln": "MVLQTQVFISLLLWISGAYGDIVMTQSPDSLAVSLGERATINCKSSQSVLYSSNNKNYLAWYQQKPGQPPKLLIYWASTRESGVPDRFSGSGSGTDFTLTISSLQAEDVAVYYCQQYYSTP-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A140T8M4-1", "uniprot_id": "A0A140T8M4_MOUSE", "id": "A0A140T8M4-1", "name": "", "aln": "--------------------DIVMTQSPSSLTVTAGEKVTMSCKSSQSLLNSGNQKNYLTWYQQKPGQPPKLLIYWASTRESGVPDRFTGSGSGTDFTLTISSVQAEDLAVYYCQNDYSYP-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZLJ1-1", "uniprot_id": "A0A8I5ZLJ1_RAT", "id": "A0A8I5ZLJ1-1", "name": "Ig-like domain-containing protein", "aln": "MHVHRP-FVT-----VGTCGDIVMTQSPSSLAVSAGEKVTMRCKTSQSLLLTSNQKNYLAWYQQKPWQSSKLLISWASPEKSGVPDRFTGSGSGTDFTLTISSVQAEDMAVYYCYQYYNYPPTVIQPPTQTS", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ********.**:*: **:.*: **:***:* :.*:****:****** *..**** ***..:*******:**************:****:***** : *. * ", "identical_positions": 71, "similar_positions": 22, "identity": "53.79%" }, { "cls_id": "homologset.agr.MGI:1330845", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P06312-1", "uniprot_id": "KV401_HUMAN", "id": "P06312-1", "name": "Immunoglobulin kappa variable 4-1", "aln": "MVLQTQVFISLLLWISGAYGDIVMTQSPDSLAVSLGERATINCKSSQSVLYSSNNKNYLAWYQQKPGQPPKLLIYWASTRESGVPDRFSGSGSGTDFTLTISSLQAEDVAVYYCQQYYSTP-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4J1J3-1", "uniprot_id": "A0A0B4J1J3_MOUSE", "id": "A0A0B4J1J3-1", "name": "", "aln": "MESQTHVLMFLLLWVSDTCGDIVMTQSPSSLAVTAGEKVTMRCKSSQSLLWSVNQNNYLSWYQQKQGQPPKLLIYGASIRESWVPDRFTGSGSGTDFTLTISNVHAEDLAVYYCQHNHGSFLP---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZLJ1-1", "uniprot_id": "A0A8I5ZLJ1_RAT", "id": "A0A8I5ZLJ1-1", "name": "Ig-like domain-containing protein", "aln": "------MHVHRPFVTVGTCGDIVMTQSPSSLAVSAGEKVTMRCKTSQSLLLTSNQKNYLAWYQQKPWQSSKLLISWASPEKSGVPDRFTGSGSGTDFTLTISSVQAEDMAVYYCYQYYNYPPTVIQPPTQTS", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : .: *********.****: **:.*:.**:***:* : *::***:***** *..**** ** .:* *****:*************.::***:***** : :. ", "identical_positions": 65, "similar_positions": 29, "identity": "49.24%" }, { "cls_id": "homologset.agr.MGI:1330848", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Y2Q0-1", "uniprot_id": "AT8A1_HUMAN", "id": "Q9Y2Q0-1", "name": "Phospholipid-transporting ATPase IA", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPTMRRTVSEIRSRAEGYEKTDDVSEKT-SLADQEEVRTIFINQPQLTK---FCNNHVSTAKYNIITFLPRFLYSQFRRAANSFFLFIALLQQIPDVSPTGRYTTLVPLLFILAVAAIKEIIEDIKRHKADNAVNKKQTQVLRNG--AWEIVHWEKVAVGEIVKVTNGEHLPADLISLSSSEPQAMCYIETSNLDGETNLKIRQGLPATSDIKDVDSLMRISGRIECESPNRHLYDFVGNIRLDGHGTVPLGADQILLRGAQLRNTQWVHGIVVYTGHDTKLMQNSTSPPLKLSNVERITNVQILILFCILIAMSLVCSVGSAIWNRRHSGKDWYLNLN-YGGASNFGLNFLTFIILFNNLIPISLLVTLEVVKFTQAYFINWDLDMHYEPTDTAAMARTSNLNEELGQVKYIFSDKTGTLTCNVMQFKKCTIAGVAYGHVPEPEDYGCSPDEWQNSQFGDEKTFSDSSLLENLQN--NHPTAPIICEFLTMMAVCHTAVPER-EGDKIIYQAASPDEGALVRAAKQLNFVFTGRTPD--SVIIDSLGQEERYELLNVLEFTSARKRMSVIVRTPSGKLRLYCKGADTVIYDRLAET-SKYKEITLKHLEQFATEGLRTLCFAVAEISESDFQEWRAVYQRASTSVQNRLLKLEESYELIEKNLQLLGATAIEDKLQDQVPETIETLMKADIKIWILTGDKQETAINIGHSCKLLKKNMGMIVINEGSLDGTRETLSRHCTTLGD---ALRKENDFALIIDGKTLKYALTFGVRQYFLDLALSCKAVICCRVSPLQKSEVVEMVKKQVKVVTLAIGDGANDVSMIQTAHVGVGISGNEGLQAANSSDYSIAQFKYLKNLLMIHGAWNYNRVSKCILYCFYKNIVLYIIEIWFAFVNGFSGQILFERWCIGLYNVMFTAMPPLTLGIFERSCRKENMLKYPELYKTSQNALDFNTKVFWVHCLNGLFHSVILFWFPLKALQYGTAFG-NGKTSDYLLLGNFVYTFVVITVCLKAGLETSYWTWFSHIAIWGSIALWVVFFGIYSSLWPAIPMAPDMSGEAAMLFSSGVFWMGLLFIPVASLLLDVVYKVIKRTAFKTLVDEVQELEAK-SQDPGAVV-------------LGKSLTERAQLLKNVFKKNHVNLYRSESLQQNLLHGYAFSQDEN---------GIVSQSEVIRAYDTTKQRPDEW--------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P70704-1", "uniprot_id": "AT8A1_MOUSE", "id": "P70704-1", "name": "Phospholipid-transporting ATPase IA", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPTMRRTVSEIRSRAEGYEKTDDVSEKT-SLADQEEVRTIFINQPQLTK---FCNNHVSTAKYNVITFLPRFLYSQFRRAANSFFLFIALLQQIPDVSPTGRYTTLVPLLFILAVAAIKEIIEDIKRHKADNAVNKKQTQVLRNG--AWEIVHWEKVAVGEIVKVTNGEHLPADLLSLSSSEPQAMCYIETSNLDGETNLKIRQGLPATSDIKDIDSLMRISGRIECESPNRHLYDFVGNIRLDGHGTVPLGADQILLRGAQLRNTQWVHGIVVYTGHDTKLMQNSTSPPLKLSNVERITNVQILILFCILIAMSLVCSVGSAIWNRRHSGKDWYLHLH-YGGASNFGLNFLTFIILFNNLIPISLLVTLEVVKFTQAYFINWDLDMHYEPTDTAAMARTSNLNEELGQVKYIFSDKTGTLTCNVMQFKKCTIAGVAYGHVPEPEDYGCSPDEWQSSQFGDEKTFNDPSLLDNLQN--NHPTAPIICEFLTMMAVCHTAVPER-EGDKIIYQAASPDEGALVRAAKQLNFVFTGRTPD--SVIIDSLGQEERYELLNVLEFTSARKRMSVVVRTPSGKLRLYCKGADTVIYERLAET-SKYKEITLKHLEQFATEGLRTLCFAVAEISESDFEEWRAVYHRASTSVQNRLLKLEESYELIEKNLQLLGATAIEDKLQDQVPETIETLMKADIKIWILTGDKQETAINIGHSCRLLKRNMGMIVINEGSLDGTRETLSRHCTTLGD---ALRKENDFALIIDGKTLKYALTFGVRQYFLDLALSCKAVICCRVSPLQKSEVVEMVKKQVKVITLAIGDGANDVSMIQTAHVGVGISGNEGLQAANSSDYSIAQFKYLKNLLMVHGAWNYNRVSKCILYCFYKNIVLYIIEIWFAFVNGFSGQILFERWCIGLYNVMFTAMPPLTLGIFERSCRKENMLKYPELYKTSQNALDFNTKVFWVHCLNGLFHSVILFWFPLKALQYGTVFG-NGKTSDYLLLGNFVYTFVVITVCLKAGLETSYWTWFSHIAIWGSIALWVVFFGIYSSLWPAVPMAPDMSGEAAMLFSSGVFWVGLLSIPVASLLLDVLYKVIKRTAFKTLVDEVQELEAK-SQDPGAVV-------------LGKSLTERAQLLKNVFKKNHVNLYRSESLQQNLLHGYAFSQDEN---------GIVSQSEVIRAYDTTKQRPDEW--------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZKC1-1", "uniprot_id": "A0A8I5ZKC1_RAT", "id": "A0A8I5ZKC1-1", "name": "Phospholipid-transporting ATPase", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MALGKLFTGK--------------SEPQAMCYIETSNLDGETNLKIRQGLPATSDIKDIDSLMRISGRIECESPNRHLYDFVGNIRLDGHGTVPLGADQILLRGAQLRNTQWVHGIVVYTGHDTKLMQNSTSPPLKLSNVERITNVQILILFCILIAMSLVCSVGSAIWNRRHSGKDWYLHLH-YGGASNFGLNFLTFIILFNNLIPISLLVTLEVVKFTQAYFINWDLDMHYEPTDTAAMARTSNLNEELGQVKYIFSDKTGTLTCNVMQFKKCTIAGVAYG---------------QSSQFGDEKTFNDPSLLENLQN--NHPTAPIICEFLTMMAVCHTAVPER-DGEKIIYQAASPDEGALVRAAKQLNFVFTGRTPD--SVIIDSLGQEERYELLNVLEFTSSRKRMSVVVRTPSGKLRLYCKGADTVIYERLAES-SKYKEITLKHLEQFATEGLRTLCFAVAEISESDFEEWRAVYQRASTSVQNRLLKLEESYELIEKNLQLLGATAIEDKLQDQVPETIETLMKADIKIWILTGDKQETAINIGHSCRLLRRNMGMIVINEGSLDGTRETLSRHCTTLGD---ALRKENDFALIIDGKTLKYALTFGVRQYFLDLALSCKAVICCRVSPLQKSEVVEMVKKQVKVITLAIGDGANDVSMIQTAHVGVGISGNEGLQAANSSDYSIAQFKYLKNLLMVHGAWNYNRVSKCILYCFYKNIVLYIIEIWFAFVNGFSGQILFERWCIGLYNVMFTAMPPLTLGIFERSCRKENMLKYPELYKTSQNALDFNTKVFWVHCLNGLFHSVILFWFPLKALQYGTVFG-NGKTSDYLLLGNFVYTFVVITVCLKAGLETSYWTWFSHIAIWGSIALWVVFFGIYSSLWPAVPMAPDMSGEAAMLFSSGVFWVGLLSIPVASLLLDVLYKVIKRTAFKTLVDEVQELEAK-SQDPGAVV-------------LGKSLTERAQLLKNVFKKNHVNLYRSESLQQNLLHGYAFSQDEN---------GIVSQSEVIRAYDTTKQRPDEW--------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B7YZF8-1", "uniprot_id": "B7YZF8_DROME", "id": "B7YZF8-1", "name": "Phospholipid-transporting ATPase", "aln": "MSGSYQRQSLELRSPDHGSVDDPDGCLRNHLGSSASQRRRQQRIAQQRQDSWFRHSMPPAINRDFESLEHLTPRASDGLDEQLAASVSHSVHSGGSVTLCGPPDHSSIHLNSANSNLGFIDSDTPNTPVTPVSGLQPPASVSTSVGGTLSSRRRSSNRKDSKGSILSRQSGKSRVSLLAQRGLRMTASFLRRKRTEYEDDEDFTSSAGYDADDGERRIINLNGPQPTK---YGNNRITTAKYSFISFLPAFLFEQFRRYSNCFFLLIAILQQIPEVSPTGRYTTLVPLMFILSVSAIKEIIEDIKRHRADNEINHRSIERLDSG--SWCTVRWSELTVGDIIKVGINTFFPADLILLSSSEPQAMCFIETANLDGETNLKIRQALPATAELLETKDLQRLEGRIECELPNRHLYEFNGVLRETGKPPAALGNDQVLQRGAILRNTAWVFGIVVYSGQETKLMKNSTSAPLKRSTVDKLTNTQILMLFMILISLCIISGLCNLFWTREHSETDWYLGLT-DFKTKSLGYNLLTFFILYNNLIPISLQVTLELVRFLQAIFINYDIEMYHEESNTPAMARTSNLNEELGMVKYIFSDKTGTLTQNVMEFKKCSIAGYVYT---------------------AERTPEESQLVQNILG--RHETSAVIEEFLELLSVCHTVIPERKENGNMIYHAASPDERALVEGAQKFGYIFDTRTPK--YVEINALGVRKRYEVLNVLEFTSSRKRMSLIVRTPENKIKLFCKGADTVIYERLAPQGQAFREQTLRHLEEFASDGLRTLCLAVADIRPDVYQEWSQTFDKASVALQNRESKLEDAANLIENNLRLLGATAIEDRLQDGVPETIASLLDAGIYIWVLTGDKQETAINIGYSCRLISHSMDIIILNEESLDATREVIHRHYGEFKS---SSAKDANVALVIDGTTLKYALSCDLRNDFQDLCILCRVVICCRVSPMQKAEVVEMVTQSTNAVTLAIGDGANDVAMIQKANVGIGISGVEGLQAACASDYSIAQFRYLQRLLLVHGAWNYARISKLILYSFYKNVCLYVIELWFAVYSGWSGQILFERWTIGLYNVLFTAMPPFAMGLFEKFCTAETMIRYPMLYKTSQNAKLFNVKVFWIWIFNALLHSVFLFWLPLAAYTKEVIWS-DGKTSDYLLMGNLVYTYVIVTVCLKAGLITNSWTWLTHLAIWGSIVLWFGFLLIYSHVWPMFKFASNFRGMDIQLLSTPVFYFCLMLVPITTLLIDVICKLVHNTVFKTLTEAVRETEIR-RSDISEVMNEPRSSDSGFGYALGKLIRSSHILISHDHHPVSESSRTSNLRVENLEMEADTEQQQQSRQRQKWRGGQVATGVARSARNSTTSPITATLHM-----------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39524-1", "uniprot_id": "ATC3_YEAST", "id": "P39524-1", "name": "Phospholipid-transporting ATPase DRS2", "aln": "--MNDDRETPPKRKPG----EDDTLFDIDFLDDTTSHSGSRSKVTNSHANAN---YIPPS---------HVLPEETIDLDAD-DDNIENDVHENLFMSN-NHDDQTSWNANRFDS-----DAYQPQS----LRAVKPPG-LFARFGNGLKNAFTFKRKKGPESFEMNHYNAVTNNELDDNYLDSRNKFNIKILFNRYILRKNVGDAE----GNGEPRVIHINDSLANSSFGYSDNHISTTKYNFATFLPKFLFQEFSKYANLFFLCTSAIQQVPHVSPTNRYTTIGTLLVVLIVSAMKECIEDIKRANSDKELNNSTAEIFSEAHDDFVEKRWIDIRVGDIIRVKSEEPIPADTIILSSSEPEGLCYIETANLDGETNLKIKQSRVETAKFIDVKTLKNMNGKVVSEQPNSSLYTYEGTMTLNDR-QIPLSPDQMILRGATLRNTAWIFGLVIFTGHETKLLRNATATPIKRTAVEKIINRQIIALFTVLIVLILISSIGNVIMSTADAKHLSYLYLEGTNKAGLFFKDFLTFWILFSNLVPISLFVTVELIKYYQAFMIGSDLDLYYEKTDTPTVVRTSSLVEELGQIEYIFSDKTGTLTRNIMEFKSCSIAGHCYIDKIPE-------DKTATVEDGIEVGYRKFDDLKKKLNDPSDEDSPIINDFLTLLATCHTVIPEFQSDGSIKYQAASPDEGALVQGGADLGYKFIIRKPNSVTVLLEETGEEKEYQLLNICEFNSTRKRMSAIFRFPDGSIKLFCKGADTVILERLDDEANQYVEATMRHLEDYASEGLRTLCLAMRDISEGEYEEWNSIYNEAATTLDNRAEKLDEAANLIEKNLILIGATAIEDKLQDGVPETIHTLQEAGIKIWVLTGDRQETAINIGMSCRLLSEDMNLLIINEETRDDTERNLLEKINALNEHQLSTHDMNTLALVIDGKSLGFALEPELEDYLLTVAKLCKAVICCRVSPLQKALVVKMVKRKSSSLLLAIGDGANDVSMIQAAHVGVGISGMEGMQAARSADIAVGQFKFLKKLLLVHGSWSYQRISVAILYSFYKNTALYMTQFWYVFANAFSGQSIMESWTMSFYNLFFTVWPPFVIGVFDQFVSSRLLERYPQLYKLGQKGQFFSVYIFWGWIINGFFHSAIVFIGTILIYRYGFALNMHGELADHWSWGVTVYTTSVIIVLGKAALVTNQWTKFTLIAIPGSLLFWLIFFPIYASIFPHANISREYYGVVKHTYGSGVFWLTLIVLPIFALVRDFLWKYYKRMYEPETYHVIQEMQKYNISDSRPHVQQ-----------FQNAIRKVRQVQRMKKQRGFAFSQAEEGGQEKIVRMYDTTQKRG-------KYGELQDASANPFNDNNGLGSNDFESAEPFIENPFADGNQNSNRFSSSRDDISFDI", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :*.:. ***:.:*:***:**********:*. *:.: : . * .:.*:: .* ** ** : * : .: .*. **:: *** **** *:.*:*:::*::***::*:*:.*:* : *::: * **: ** :** : ::..: . : . .: ** * : : ::*** **:.**:**** **:*:::: ** :*. *:::::* ::*.::.***.* **** ::*********** *:*:**.*:*** * * . . :.: . . :.:* :** :::.***.:** .. .: *:****** ***... .:.: * *.*. * :: * .:.*::**: **.*:***** :.* *...::*:******** :** . : * *::***::*::******:*: :* . ::** :..*:.:::** **::: :***:** *:*******:*** ***** :* .*.* **:****:******** **:*: ..*.::::** : * *.. : .: : . : . .**:***.:* :** :.: : :. *:.********:**: **:**.:. . : **********:*** *:**:**** **:*** ::* ::.**::*:.**::**:*.* *:* ***.**** **: ::*:.. ..:*** ::* * :.:**::**. **:.:*:*:: . : :** *** .*:. *.. :** :*.::**.::* .: . .*: :*: * *** :: * **.* *. ** :: :** **: :*. *: **: ::* :: : * .: **:. *: :*: :*: *.: * :. . ::* : .* : : : : . : : .: ::: *.. * : . . :.. ", "identical_positions": 353, "similar_positions": 338, "identity": "24.95%" }, { "cls_id": "homologset.agr.MGI:1330849", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P01619-1", "uniprot_id": "KV320_HUMAN", "id": "P01619-1", "name": "Immunoglobulin kappa variable 3-20", "aln": "ME---TPAQLLFLLLLWLPDTTGEIVLTQSPGTLSLSPGERATLSCRASQSVSSS---YLAWYQQKPGQAPRLLIYGASSRATGIPDRFSGSGSGTDFTLTISRLEPEDFAVYYCQQYGSSP------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0C4DH25-1", "uniprot_id": "KVD20_HUMAN", "id": "A0A0C4DH25-1", "name": "Immunoglobulin kappa variable 3D-20", "aln": "ME---TPAQLLFLLLLWLPDTTGEIVLTQSPATLSLSPGERATLSCGASQSVSSS---YLAWYQQKPGLAPRLLIYDASSRATGIPDRFSGSGSGTDFTLTISRLEPEDFAVYYCQQYGSSP------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P04433-1", "uniprot_id": "KV311_HUMAN", "id": "P04433-1", "name": "Immunoglobulin kappa variable 3-11", "aln": "ME---APAQLLFLLLLWLPDTTGEIVLTQSPATLSLSPGERATLSCRASQSVSS----YLAWYQQKPGQAPRLLIYDASNRATGIPARFSGSGSGTDFTLTISSLEPEDFAVYYCQQRSNWP------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0A0MRZ8-1", "uniprot_id": "KVD11_HUMAN", "id": "A0A0A0MRZ8-1", "name": "Immunoglobulin kappa variable 3D-11", "aln": "ME---APAQLLFLLLLWLPDTTGEIVLTQSPATLSLSPGERATLSCRASQSVSS----YLAWYQQKPGQAPRLLIYDASNRATGIPARFSGSGPGTDFTLTISSLEPEDFAVYYCQQRSNWH------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P01624-1", "uniprot_id": "KV315_HUMAN", "id": "P01624-1", "name": "Immunoglobulin kappa variable 3-15", "aln": "ME---APAQLLFLLLLWLPDTTGEIVMTQSPATLSVSPGERATLSCRASQSVSSN----LAWYQQKPGQAPRLLIYGASTRATGIPARFSGSGSGTEFTLTISSLQSEDFAVYYCQQYNNWP------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A087WSY6-1", "uniprot_id": "KVD15_HUMAN", "id": "A0A087WSY6-1", "name": "Immunoglobulin kappa variable 3D-15", "aln": "ME---APAQLLFLLLLWLPDTTGEIVMTQSPATLSVSPGERATLSCRASQSVSSN----LAWYQQKPGQAPRLLIYGASIRATGIPARFSGSGSGTEFTLTISILQSEDFAVYYCQQYNNWP------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A075B6H7-1", "uniprot_id": "KV37_HUMAN", "id": "A0A075B6H7-1", "name": "Probable non-functional immunoglobulin kappa variable 3-7", "aln": "ME---APAQLLFLLLLWLPDTTREIVMTQSPPTLSLSPGERVTLSCRASQSVSSS---YLTWYQQKPGQAPRLLIYGASTRATSIPARFSGSGSGTDFTLTISSLQPEDFAVYYCQQDYNLP------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0C4DH90-1", "uniprot_id": "A0A0C4DH90_HUMAN", "id": "A0A0C4DH90-1", "name": "", "aln": "ME---APAQLLFLLLLWLPDTTGEIVMTQSPATLSLSPGERATLSCRASQSVSSS---YLSWYQQKPGQAPRLLIYGASTRATGIPARFSGSGSGTDFTLTISSLQPEDFAVYYCQQDYNLP------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0C4DH55-1", "uniprot_id": "KVD07_HUMAN", "id": "A0A0C4DH55-1", "name": "Immunoglobulin kappa variable 3D-7", "aln": "MEPWKPQHSFFFLLLLWLPDTTGEIVMTQSPATLSLSPGERATLSCRASQSVSSS---YLSWYQQKPGQAPRLLIYGASTRATGIPARFSGSGSGTDFTLTISSLQPEDFAVYYCQQDYNLP------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6AKA7-1", "uniprot_id": "A0A8I6AKA7_RAT", "id": "A0A8I6AKA7-1", "name": "", "aln": "MEC-----------VFIISGSTGDIVLTQSPA-LAVSLGQRATISCRASQSVSTSSYNLMHWYQQKPGEQPKLLIYDASNLASGIPVRFSGSGSGTDFTLTINPVQADDIATYYCQQSRELPPTVVQG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A140T8Q0-1", "uniprot_id": "A0A140T8Q0_MOUSE", "id": "A0A140T8Q0-1", "name": "", "aln": "MESD---TLLLWVLLLWVPGSTGDIVLTQSPASLAVSLGQRATIFCRASQSVDYNGISYMHWFQQKPGQPPKLLIYAASNLESGIPARFSGSGSGTDFTLNIHPVEEEDAATYYCQQSIEDP------", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** :: :..:* :**:**** *::* *:*.*: * *****. : *:***** *:**** ** :.** ******.**:***.* :: :* *.***** . ", "identical_positions": 54, "similar_positions": 27, "identity": "42.19%" }, { "cls_id": "homologset.agr.MGI:1330850", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P01619-1", "uniprot_id": "KV320_HUMAN", "id": "P01619-1", "name": "Immunoglobulin kappa variable 3-20", "aln": "ME---TPAQLLFLLLLWLPDTTGEIVLTQSPGTLSLSPGERATLSCRASQSVSSS---YLAWYQQKPGQAPRLLIYGASSRATGIPDRFSGSGSGTDFTLTISRLEPEDFAVYYCQQYGSSP------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0C4DH25-1", "uniprot_id": "KVD20_HUMAN", "id": "A0A0C4DH25-1", "name": "Immunoglobulin kappa variable 3D-20", "aln": "ME---TPAQLLFLLLLWLPDTTGEIVLTQSPATLSLSPGERATLSCGASQSVSSS---YLAWYQQKPGLAPRLLIYDASSRATGIPDRFSGSGSGTDFTLTISRLEPEDFAVYYCQQYGSSP------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P04433-1", "uniprot_id": "KV311_HUMAN", "id": "P04433-1", "name": "Immunoglobulin kappa variable 3-11", "aln": "ME---APAQLLFLLLLWLPDTTGEIVLTQSPATLSLSPGERATLSCRASQSVSS----YLAWYQQKPGQAPRLLIYDASNRATGIPARFSGSGSGTDFTLTISSLEPEDFAVYYCQQRSNWP------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0A0MRZ8-1", "uniprot_id": "KVD11_HUMAN", "id": "A0A0A0MRZ8-1", "name": "Immunoglobulin kappa variable 3D-11", "aln": "ME---APAQLLFLLLLWLPDTTGEIVLTQSPATLSLSPGERATLSCRASQSVSS----YLAWYQQKPGQAPRLLIYDASNRATGIPARFSGSGPGTDFTLTISSLEPEDFAVYYCQQRSNWH------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P01624-1", "uniprot_id": "KV315_HUMAN", "id": "P01624-1", "name": "Immunoglobulin kappa variable 3-15", "aln": "ME---APAQLLFLLLLWLPDTTGEIVMTQSPATLSVSPGERATLSCRASQSVSSN----LAWYQQKPGQAPRLLIYGASTRATGIPARFSGSGSGTEFTLTISSLQSEDFAVYYCQQYNNWP------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A087WSY6-1", "uniprot_id": "KVD15_HUMAN", "id": "A0A087WSY6-1", "name": "Immunoglobulin kappa variable 3D-15", "aln": "ME---APAQLLFLLLLWLPDTTGEIVMTQSPATLSVSPGERATLSCRASQSVSSN----LAWYQQKPGQAPRLLIYGASIRATGIPARFSGSGSGTEFTLTISILQSEDFAVYYCQQYNNWP------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A075B6H7-1", "uniprot_id": "KV37_HUMAN", "id": "A0A075B6H7-1", "name": "Probable non-functional immunoglobulin kappa variable 3-7", "aln": "ME---APAQLLFLLLLWLPDTTREIVMTQSPPTLSLSPGERVTLSCRASQSVSSS---YLTWYQQKPGQAPRLLIYGASTRATSIPARFSGSGSGTDFTLTISSLQPEDFAVYYCQQDYNLP------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0C4DH90-1", "uniprot_id": "A0A0C4DH90_HUMAN", "id": "A0A0C4DH90-1", "name": "", "aln": "ME---APAQLLFLLLLWLPDTTGEIVMTQSPATLSLSPGERATLSCRASQSVSSS---YLSWYQQKPGQAPRLLIYGASTRATGIPARFSGSGSGTDFTLTISSLQPEDFAVYYCQQDYNLP------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0C4DH55-1", "uniprot_id": "KVD07_HUMAN", "id": "A0A0C4DH55-1", "name": "Immunoglobulin kappa variable 3D-7", "aln": "MEPWKPQHSFFFLLLLWLPDTTGEIVMTQSPATLSLSPGERATLSCRASQSVSSS---YLSWYQQKPGQAPRLLIYGASTRATGIPARFSGSGSGTDFTLTISSLQPEDFAVYYCQQDYNLP------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6AKA7-1", "uniprot_id": "A0A8I6AKA7_RAT", "id": "A0A8I6AKA7-1", "name": "", "aln": "-----------MECVFIISGSTGDIVLTQSPA-LAVSLGQRATISCRASQSVSTSSYNLMHWYQQKPGEQPKLLIYDASNLASGIPVRFSGSGSGTDFTLTINPVQADDIATYYCQQSRELPPTVVQG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "M0RCN6-1", "uniprot_id": "M0RCN6_RAT", "id": "M0RCN6-1", "name": "", "aln": "-----------MVCVFLFPGSTGDTVLTQSPA-LAVSPGERVSISCRASEGVN--SY--MHWYQQKPGQQPKLLIYKASNLASGVPARFSGSGSGTDFTLTIDPVEADDTATYFCQQSWNDPPTVLQG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A075B5P0-1", "uniprot_id": "A0A075B5P0_MOUSE", "id": "A0A075B5P0-1", "name": "", "aln": "ME---KDTLLLWVLLLWVPGSTGDIVLTQSPASLAVSLGQRATISCRASESVDNYGISFMNWFQQKPGQPPKLLIYAASNQGSGVPARFSGSGSGTDFSLNIHPMEEDDTAMYFCQQSKEVP------", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: ...:* : *:**** *::* *:*.::** **:.*. : *:***** *:**** ** .:.:* ******.**:*:*.* :: :* * *:*** . ", "identical_positions": 46, "similar_positions": 33, "identity": "35.94%" }, { "cls_id": "homologset.agr.MGI:1330851", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P01619-1", "uniprot_id": "KV320_HUMAN", "id": "P01619-1", "name": "Immunoglobulin kappa variable 3-20", "aln": "ME---TPAQLLFLLLLWLPDTTGEIVLTQSPGTLSLSPGERATLSCRASQSVSSS---YLAWYQQKPGQAPRLLIYGASSRATGIPDRFSGSGSGTDFTLTISRLEPEDFAVYYCQQYGSSP------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0C4DH25-1", "uniprot_id": "KVD20_HUMAN", "id": "A0A0C4DH25-1", "name": "Immunoglobulin kappa variable 3D-20", "aln": "ME---TPAQLLFLLLLWLPDTTGEIVLTQSPATLSLSPGERATLSCGASQSVSSS---YLAWYQQKPGLAPRLLIYDASSRATGIPDRFSGSGSGTDFTLTISRLEPEDFAVYYCQQYGSSP------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P04433-1", "uniprot_id": "KV311_HUMAN", "id": "P04433-1", "name": "Immunoglobulin kappa variable 3-11", "aln": "ME---APAQLLFLLLLWLPDTTGEIVLTQSPATLSLSPGERATLSCRASQSVSS----YLAWYQQKPGQAPRLLIYDASNRATGIPARFSGSGSGTDFTLTISSLEPEDFAVYYCQQRSNWP------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0A0MRZ8-1", "uniprot_id": "KVD11_HUMAN", "id": "A0A0A0MRZ8-1", "name": "Immunoglobulin kappa variable 3D-11", "aln": "ME---APAQLLFLLLLWLPDTTGEIVLTQSPATLSLSPGERATLSCRASQSVSS----YLAWYQQKPGQAPRLLIYDASNRATGIPARFSGSGPGTDFTLTISSLEPEDFAVYYCQQRSNWH------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P01624-1", "uniprot_id": "KV315_HUMAN", "id": "P01624-1", "name": "Immunoglobulin kappa variable 3-15", "aln": "ME---APAQLLFLLLLWLPDTTGEIVMTQSPATLSVSPGERATLSCRASQSVSSN----LAWYQQKPGQAPRLLIYGASTRATGIPARFSGSGSGTEFTLTISSLQSEDFAVYYCQQYNNWP------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A087WSY6-1", "uniprot_id": "KVD15_HUMAN", "id": "A0A087WSY6-1", "name": "Immunoglobulin kappa variable 3D-15", "aln": "ME---APAQLLFLLLLWLPDTTGEIVMTQSPATLSVSPGERATLSCRASQSVSSN----LAWYQQKPGQAPRLLIYGASIRATGIPARFSGSGSGTEFTLTISILQSEDFAVYYCQQYNNWP------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A075B6H7-1", "uniprot_id": "KV37_HUMAN", "id": "A0A075B6H7-1", "name": "Probable non-functional immunoglobulin kappa variable 3-7", "aln": "ME---APAQLLFLLLLWLPDTTREIVMTQSPPTLSLSPGERVTLSCRASQSVSSS---YLTWYQQKPGQAPRLLIYGASTRATSIPARFSGSGSGTDFTLTISSLQPEDFAVYYCQQDYNLP------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0C4DH90-1", "uniprot_id": "A0A0C4DH90_HUMAN", "id": "A0A0C4DH90-1", "name": "", "aln": "ME---APAQLLFLLLLWLPDTTGEIVMTQSPATLSLSPGERATLSCRASQSVSSS---YLSWYQQKPGQAPRLLIYGASTRATGIPARFSGSGSGTDFTLTISSLQPEDFAVYYCQQDYNLP------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0C4DH55-1", "uniprot_id": "KVD07_HUMAN", "id": "A0A0C4DH55-1", "name": "Immunoglobulin kappa variable 3D-7", "aln": "MEPWKPQHSFFFLLLLWLPDTTGEIVMTQSPATLSLSPGERATLSCRASQSVSSS---YLSWYQQKPGQAPRLLIYGASTRATGIPARFSGSGSGTDFTLTISSLQPEDFAVYYCQQDYNLP------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6AKA7-1", "uniprot_id": "A0A8I6AKA7_RAT", "id": "A0A8I6AKA7-1", "name": "", "aln": "MEC-----------VFIISGSTGDIVLTQSPA-LAVSLGQRATISCRASQSVSTSSYNLMHWYQQKPGEQPKLLIYDASNLASGIPVRFSGSGSGTDFTLTINPVQADDIATYYCQQSRELPPTVVQG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A075B5P1-1", "uniprot_id": "A0A075B5P1_MOUSE", "id": "A0A075B5P1-1", "name": "", "aln": "MESD---TLLLWVLLLWVPGSTGDIVLTQSPASLAVSLGQRATISCRASESVEYYGTSLMQWYQQKPGQPPKLLIYAASNVESGVPARFSGSGSGTDFSLNIHPVEEDDIAMYFCQQSRKVP------", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** :: :..:* :**:**** *::* *:*.*:** **:**. : ******* *:**** ** :.:* ******.**:*:*.* :: :*:* *:*** . ", "identical_positions": 52, "similar_positions": 30, "identity": "40.62%" }, { "cls_id": "homologset.agr.MGI:1330852", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P04433-1", "uniprot_id": "KV311_HUMAN", "id": "P04433-1", "name": "Immunoglobulin kappa variable 3-11", "aln": "ME---APAQLLFLLLLWLPDTTGEIVLTQSPATLSLSPGERATLSCRASQSVSS----YLAWYQQKPGQAPRLLIYDASNRATGIPARFSGSGSGTDFTLTISSLEPEDFAVYYCQQRSNWP------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0A0MRZ8-1", "uniprot_id": "KVD11_HUMAN", "id": "A0A0A0MRZ8-1", "name": "Immunoglobulin kappa variable 3D-11", "aln": "ME---APAQLLFLLLLWLPDTTGEIVLTQSPATLSLSPGERATLSCRASQSVSS----YLAWYQQKPGQAPRLLIYDASNRATGIPARFSGSGPGTDFTLTISSLEPEDFAVYYCQQRSNWH------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P01619-1", "uniprot_id": "KV320_HUMAN", "id": "P01619-1", "name": "Immunoglobulin kappa variable 3-20", "aln": "ME---TPAQLLFLLLLWLPDTTGEIVLTQSPGTLSLSPGERATLSCRASQSVSSS---YLAWYQQKPGQAPRLLIYGASSRATGIPDRFSGSGSGTDFTLTISRLEPEDFAVYYCQQYGSSP------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0C4DH25-1", "uniprot_id": "KVD20_HUMAN", "id": "A0A0C4DH25-1", "name": "Immunoglobulin kappa variable 3D-20", "aln": "ME---TPAQLLFLLLLWLPDTTGEIVLTQSPATLSLSPGERATLSCGASQSVSSS---YLAWYQQKPGLAPRLLIYDASSRATGIPDRFSGSGSGTDFTLTISRLEPEDFAVYYCQQYGSSP------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P01624-1", "uniprot_id": "KV315_HUMAN", "id": "P01624-1", "name": "Immunoglobulin kappa variable 3-15", "aln": "ME---APAQLLFLLLLWLPDTTGEIVMTQSPATLSVSPGERATLSCRASQSVSSN----LAWYQQKPGQAPRLLIYGASTRATGIPARFSGSGSGTEFTLTISSLQSEDFAVYYCQQYNNWP------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A087WSY6-1", "uniprot_id": "KVD15_HUMAN", "id": "A0A087WSY6-1", "name": "Immunoglobulin kappa variable 3D-15", "aln": "ME---APAQLLFLLLLWLPDTTGEIVMTQSPATLSVSPGERATLSCRASQSVSSN----LAWYQQKPGQAPRLLIYGASIRATGIPARFSGSGSGTEFTLTISILQSEDFAVYYCQQYNNWP------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A075B6H7-1", "uniprot_id": "KV37_HUMAN", "id": "A0A075B6H7-1", "name": "Probable non-functional immunoglobulin kappa variable 3-7", "aln": "ME---APAQLLFLLLLWLPDTTREIVMTQSPPTLSLSPGERVTLSCRASQSVSSS---YLTWYQQKPGQAPRLLIYGASTRATSIPARFSGSGSGTDFTLTISSLQPEDFAVYYCQQDYNLP------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0C4DH90-1", "uniprot_id": "A0A0C4DH90_HUMAN", "id": "A0A0C4DH90-1", "name": "", "aln": "ME---APAQLLFLLLLWLPDTTGEIVMTQSPATLSLSPGERATLSCRASQSVSSS---YLSWYQQKPGQAPRLLIYGASTRATGIPARFSGSGSGTDFTLTISSLQPEDFAVYYCQQDYNLP------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0C4DH55-1", "uniprot_id": "KVD07_HUMAN", "id": "A0A0C4DH55-1", "name": "Immunoglobulin kappa variable 3D-7", "aln": "MEPWKPQHSFFFLLLLWLPDTTGEIVMTQSPATLSLSPGERATLSCRASQSVSSS---YLSWYQQKPGQAPRLLIYGASTRATGIPARFSGSGSGTDFTLTISSLQPEDFAVYYCQQDYNLP------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "M0RCN6-1", "uniprot_id": "M0RCN6_RAT", "id": "M0RCN6-1", "name": "", "aln": "-----------MVCVFLFPGSTGDTVLTQSPA-LAVSPGERVSISCRASEGVN----SYMHWYQQKPGQQPKLLIYKASNLASGVPARFSGSGSGTDFTLTIDPVEADDTATYFCQQSWNDPPTVLQG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A075B5N9-1", "uniprot_id": "A0A075B5N9_MOUSE", "id": "A0A075B5N9-1", "name": "", "aln": "-----------------------DIVLTQSPASLAVSLGQRATISCRASQSVSTSSYSYMHWYQQKPGQPPKLLIKYASNLESGVPARFSGSGSGTDFTLNIHPVEEEDTATYYCQHSWEIP------", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *:**** *::* *:*.::** **:.*. : ******* *:*** ** :.:* ******.**:***.* :: :* *.*:**: . ", "identical_positions": 45, "similar_positions": 26, "identity": "35.16%" }, { "cls_id": "homologset.agr.MGI:1330854", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P01619-1", "uniprot_id": "KV320_HUMAN", "id": "P01619-1", "name": "Immunoglobulin kappa variable 3-20", "aln": "ME---TPAQLLFLLLLWLPDTTGEIVLTQSPGTLSLSPGERATLSCRASQSVSSS---YLAWYQQKPGQAPRLLIYGASSRATGIPDRFSGSGSGTDFTLTISRLEPEDFAVYYCQQYGSSP------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0C4DH25-1", "uniprot_id": "KVD20_HUMAN", "id": "A0A0C4DH25-1", "name": "Immunoglobulin kappa variable 3D-20", "aln": "ME---TPAQLLFLLLLWLPDTTGEIVLTQSPATLSLSPGERATLSCGASQSVSSS---YLAWYQQKPGLAPRLLIYDASSRATGIPDRFSGSGSGTDFTLTISRLEPEDFAVYYCQQYGSSP------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P04433-1", "uniprot_id": "KV311_HUMAN", "id": "P04433-1", "name": "Immunoglobulin kappa variable 3-11", "aln": "ME---APAQLLFLLLLWLPDTTGEIVLTQSPATLSLSPGERATLSCRASQSVSS----YLAWYQQKPGQAPRLLIYDASNRATGIPARFSGSGSGTDFTLTISSLEPEDFAVYYCQQRSNWP------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0A0MRZ8-1", "uniprot_id": "KVD11_HUMAN", "id": "A0A0A0MRZ8-1", "name": "Immunoglobulin kappa variable 3D-11", "aln": "ME---APAQLLFLLLLWLPDTTGEIVLTQSPATLSLSPGERATLSCRASQSVSS----YLAWYQQKPGQAPRLLIYDASNRATGIPARFSGSGPGTDFTLTISSLEPEDFAVYYCQQRSNWH------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P01624-1", "uniprot_id": "KV315_HUMAN", "id": "P01624-1", "name": "Immunoglobulin kappa variable 3-15", "aln": "ME---APAQLLFLLLLWLPDTTGEIVMTQSPATLSVSPGERATLSCRASQSVSSN----LAWYQQKPGQAPRLLIYGASTRATGIPARFSGSGSGTEFTLTISSLQSEDFAVYYCQQYNNWP------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A087WSY6-1", "uniprot_id": "KVD15_HUMAN", "id": "A0A087WSY6-1", "name": "Immunoglobulin kappa variable 3D-15", "aln": "ME---APAQLLFLLLLWLPDTTGEIVMTQSPATLSVSPGERATLSCRASQSVSSN----LAWYQQKPGQAPRLLIYGASIRATGIPARFSGSGSGTEFTLTISILQSEDFAVYYCQQYNNWP------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A075B6H7-1", "uniprot_id": "KV37_HUMAN", "id": "A0A075B6H7-1", "name": "Probable non-functional immunoglobulin kappa variable 3-7", "aln": "ME---APAQLLFLLLLWLPDTTREIVMTQSPPTLSLSPGERVTLSCRASQSVSSS---YLTWYQQKPGQAPRLLIYGASTRATSIPARFSGSGSGTDFTLTISSLQPEDFAVYYCQQDYNLP------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0C4DH90-1", "uniprot_id": "A0A0C4DH90_HUMAN", "id": "A0A0C4DH90-1", "name": "", "aln": "ME---APAQLLFLLLLWLPDTTGEIVMTQSPATLSLSPGERATLSCRASQSVSSS---YLSWYQQKPGQAPRLLIYGASTRATGIPARFSGSGSGTDFTLTISSLQPEDFAVYYCQQDYNLP------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0C4DH55-1", "uniprot_id": "KVD07_HUMAN", "id": "A0A0C4DH55-1", "name": "Immunoglobulin kappa variable 3D-7", "aln": "MEPWKPQHSFFFLLLLWLPDTTGEIVMTQSPATLSLSPGERATLSCRASQSVSSS---YLSWYQQKPGQAPRLLIYGASTRATGIPARFSGSGSGTDFTLTISSLQPEDFAVYYCQQDYNLP------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6AKA7-1", "uniprot_id": "A0A8I6AKA7_RAT", "id": "A0A8I6AKA7-1", "name": "", "aln": "-----------MECVFIISGSTGDIVLTQSPA-LAVSLGQRATISCRASQSVSTSSYNLMHWYQQKPGEQPKLLIYDASNLASGIPVRFSGSGSGTDFTLTINPVQADDIATYYCQQSRELPPTVVQG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "M0RCN6-1", "uniprot_id": "M0RCN6_RAT", "id": "M0RCN6-1", "name": "", "aln": "-----------MVCVFLFPGSTGDTVLTQSPA-LAVSPGERVSISCRASEGVN--SY--MHWYQQKPGQQPKLLIYKASNLASGVPARFSGSGSGTDFTLTIDPVEADDTATYFCQQSWNDPPTVLQG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A140T8M6-1", "uniprot_id": "A0A140T8M6_MOUSE", "id": "A0A140T8M6-1", "name": "", "aln": "ME---TDTLLLWVLLLWVPGSTGDIVLTQSPASLAVSLGQRATISCRASESVDSYGNSFMHWYQQKPGQPPKLLIYRASNLESGIPARFSGSGSRTDFTLTINPVEADDVATYYCQQSNEDP------", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: ...:* : *:**** *::* *:*.::** **:.*. : ******* *:**** ** :.:* ******. *:*****. ::.:* *.*:*** . ", "identical_positions": 48, "similar_positions": 32, "identity": "37.5%" }, { "cls_id": "homologset.agr.MGI:1330855", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P01619-1", "uniprot_id": "KV320_HUMAN", "id": "P01619-1", "name": "Immunoglobulin kappa variable 3-20", "aln": "ME---TPAQLLFLLLLWLPDTTGEIVLTQSPGTLSLSPGERATLSCRASQSVSSS---YLAWYQQKPGQAPRLLIYGASSRATGIPDRFSGSGSGTDFTLTISRLEPEDFAVYYCQQYGSSP------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0C4DH25-1", "uniprot_id": "KVD20_HUMAN", "id": "A0A0C4DH25-1", "name": "Immunoglobulin kappa variable 3D-20", "aln": "ME---TPAQLLFLLLLWLPDTTGEIVLTQSPATLSLSPGERATLSCGASQSVSSS---YLAWYQQKPGLAPRLLIYDASSRATGIPDRFSGSGSGTDFTLTISRLEPEDFAVYYCQQYGSSP------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P04433-1", "uniprot_id": "KV311_HUMAN", "id": "P04433-1", "name": "Immunoglobulin kappa variable 3-11", "aln": "ME---APAQLLFLLLLWLPDTTGEIVLTQSPATLSLSPGERATLSCRASQSVSS----YLAWYQQKPGQAPRLLIYDASNRATGIPARFSGSGSGTDFTLTISSLEPEDFAVYYCQQRSNWP------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0A0MRZ8-1", "uniprot_id": "KVD11_HUMAN", "id": "A0A0A0MRZ8-1", "name": "Immunoglobulin kappa variable 3D-11", "aln": "ME---APAQLLFLLLLWLPDTTGEIVLTQSPATLSLSPGERATLSCRASQSVSS----YLAWYQQKPGQAPRLLIYDASNRATGIPARFSGSGPGTDFTLTISSLEPEDFAVYYCQQRSNWH------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P01624-1", "uniprot_id": "KV315_HUMAN", "id": "P01624-1", "name": "Immunoglobulin kappa variable 3-15", "aln": "ME---APAQLLFLLLLWLPDTTGEIVMTQSPATLSVSPGERATLSCRASQSVSSN----LAWYQQKPGQAPRLLIYGASTRATGIPARFSGSGSGTEFTLTISSLQSEDFAVYYCQQYNNWP------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A087WSY6-1", "uniprot_id": "KVD15_HUMAN", "id": "A0A087WSY6-1", "name": "Immunoglobulin kappa variable 3D-15", "aln": "ME---APAQLLFLLLLWLPDTTGEIVMTQSPATLSVSPGERATLSCRASQSVSSN----LAWYQQKPGQAPRLLIYGASIRATGIPARFSGSGSGTEFTLTISILQSEDFAVYYCQQYNNWP------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A075B6H7-1", "uniprot_id": "KV37_HUMAN", "id": "A0A075B6H7-1", "name": "Probable non-functional immunoglobulin kappa variable 3-7", "aln": "ME---APAQLLFLLLLWLPDTTREIVMTQSPPTLSLSPGERVTLSCRASQSVSSS---YLTWYQQKPGQAPRLLIYGASTRATSIPARFSGSGSGTDFTLTISSLQPEDFAVYYCQQDYNLP------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0C4DH90-1", "uniprot_id": "A0A0C4DH90_HUMAN", "id": "A0A0C4DH90-1", "name": "", "aln": "ME---APAQLLFLLLLWLPDTTGEIVMTQSPATLSLSPGERATLSCRASQSVSSS---YLSWYQQKPGQAPRLLIYGASTRATGIPARFSGSGSGTDFTLTISSLQPEDFAVYYCQQDYNLP------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0C4DH55-1", "uniprot_id": "KVD07_HUMAN", "id": "A0A0C4DH55-1", "name": "Immunoglobulin kappa variable 3D-7", "aln": "MEPWKPQHSFFFLLLLWLPDTTGEIVMTQSPATLSLSPGERATLSCRASQSVSSS---YLSWYQQKPGQAPRLLIYGASTRATGIPARFSGSGSGTDFTLTISSLQPEDFAVYYCQQDYNLP------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6AKA7-1", "uniprot_id": "A0A8I6AKA7_RAT", "id": "A0A8I6AKA7-1", "name": "", "aln": "MEC-----------VFIISGSTGDIVLTQSPA-LAVSLGQRATISCRASQSVSTSSYNLMHWYQQKPGEQPKLLIYDASNLASGIPVRFSGSGSGTDFTLTINPVQADDIATYYCQQSRELPPTVVQG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A140T8Q4-1", "uniprot_id": "A0A140T8Q4_MOUSE", "id": "A0A140T8Q4-1", "name": "", "aln": "METD---TILLWVLLLWVPGSTGDIVLTQSPASLAVSLGQRATISCKASQSVDYDGDSYMNWYQQKPGQPPKLLIYAASNLESGIPARFSGSGSGTDFTLNIHPVEEEDAATYYCQQSNEDP------", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** :: :..:* :**:**** *::* *:*.*:** *****. : ******* *:**** ** :.** ******.**:***.* :: :* *.***** . ", "identical_positions": 56, "similar_positions": 26, "identity": "43.75%" }, { "cls_id": "homologset.agr.MGI:1330856", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P01619-1", "uniprot_id": "KV320_HUMAN", "id": "P01619-1", "name": "Immunoglobulin kappa variable 3-20", "aln": "ME---TPAQLLFLLLLWLPDTTGEIVLTQSPGTLSLSPGERATLSCRASQSVSSSY---LAWYQQKPGQAPRLLIYGASSRATGIPDRFSGSGSGTDFTLTISRLEPEDFAVYYCQQYGSSP------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0C4DH25-1", "uniprot_id": "KVD20_HUMAN", "id": "A0A0C4DH25-1", "name": "Immunoglobulin kappa variable 3D-20", "aln": "ME---TPAQLLFLLLLWLPDTTGEIVLTQSPATLSLSPGERATLSCGASQSVSSSY---LAWYQQKPGLAPRLLIYDASSRATGIPDRFSGSGSGTDFTLTISRLEPEDFAVYYCQQYGSSP------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P04433-1", "uniprot_id": "KV311_HUMAN", "id": "P04433-1", "name": "Immunoglobulin kappa variable 3-11", "aln": "ME---APAQLLFLLLLWLPDTTGEIVLTQSPATLSLSPGERATLSCRASQSVSSY----LAWYQQKPGQAPRLLIYDASNRATGIPARFSGSGSGTDFTLTISSLEPEDFAVYYCQQRSNWP------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0A0MRZ8-1", "uniprot_id": "KVD11_HUMAN", "id": "A0A0A0MRZ8-1", "name": "Immunoglobulin kappa variable 3D-11", "aln": "ME---APAQLLFLLLLWLPDTTGEIVLTQSPATLSLSPGERATLSCRASQSVSSY----LAWYQQKPGQAPRLLIYDASNRATGIPARFSGSGPGTDFTLTISSLEPEDFAVYYCQQRSNWH------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P01624-1", "uniprot_id": "KV315_HUMAN", "id": "P01624-1", "name": "Immunoglobulin kappa variable 3-15", "aln": "ME---APAQLLFLLLLWLPDTTGEIVMTQSPATLSVSPGERATLSCRASQSVSSN----LAWYQQKPGQAPRLLIYGASTRATGIPARFSGSGSGTEFTLTISSLQSEDFAVYYCQQYNNWP------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A087WSY6-1", "uniprot_id": "KVD15_HUMAN", "id": "A0A087WSY6-1", "name": "Immunoglobulin kappa variable 3D-15", "aln": "ME---APAQLLFLLLLWLPDTTGEIVMTQSPATLSVSPGERATLSCRASQSVSSN----LAWYQQKPGQAPRLLIYGASIRATGIPARFSGSGSGTEFTLTISILQSEDFAVYYCQQYNNWP------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A075B6H7-1", "uniprot_id": "KV37_HUMAN", "id": "A0A075B6H7-1", "name": "Probable non-functional immunoglobulin kappa variable 3-7", "aln": "ME---APAQLLFLLLLWLPDTTREIVMTQSPPTLSLSPGERVTLSCRASQSVSSSY---LTWYQQKPGQAPRLLIYGASTRATSIPARFSGSGSGTDFTLTISSLQPEDFAVYYCQQDYNLP------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0C4DH90-1", "uniprot_id": "A0A0C4DH90_HUMAN", "id": "A0A0C4DH90-1", "name": "", "aln": "ME---APAQLLFLLLLWLPDTTGEIVMTQSPATLSLSPGERATLSCRASQSVSSSY---LSWYQQKPGQAPRLLIYGASTRATGIPARFSGSGSGTDFTLTISSLQPEDFAVYYCQQDYNLP------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0C4DH55-1", "uniprot_id": "KVD07_HUMAN", "id": "A0A0C4DH55-1", "name": "Immunoglobulin kappa variable 3D-7", "aln": "MEPWKPQHSFFFLLLLWLPDTTGEIVMTQSPATLSLSPGERATLSCRASQSVSSSY---LSWYQQKPGQAPRLLIYGASTRATGIPARFSGSGSGTDFTLTISSLQPEDFAVYYCQQDYNLP------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6AKA7-1", "uniprot_id": "A0A8I6AKA7_RAT", "id": "A0A8I6AKA7-1", "name": "", "aln": "MEC-----------VFIISGSTGDIVLTQSPA-LAVSLGQRATISCRASQSVSTSSYNLMHWYQQKPGEQPKLLIYDASNLASGIPVRFSGSGSGTDFTLTINPVQADDIATYYCQQSRELPPTVVQG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A140T8P4-1", "uniprot_id": "A0A140T8P4_MOUSE", "id": "A0A140T8P4-1", "name": "", "aln": "METD---PLLLWVLLLWVPGSTGDIVLTQSPASLAVSLGQRATISCQASESVSFAGTSLMHWYQQKPGQPPKLLIYRASNLESGVPARFSGSGSESDFTLTIDPVEEDDAAMYYCMQSMEDP------", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** :: :..:* :**:**** *::* *:*.*:** **:*** : ******* *:**** ** :.:* ******. ::*****. :: :* * *** * . ", "identical_positions": 53, "similar_positions": 27, "identity": "41.41%" }, { "cls_id": "homologset.agr.MGI:1330858", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z252-1", "uniprot_id": "LIN7B_RAT", "id": "Q9Z252-1", "name": "Protein lin-7 homolog B", "aln": "MAALVEPLGLERDVSRAVELLERLQRSGELPPQKLQALQRVLQSRFCSAIREVYEQLYDTLDITGSAEVRAHATAKATVAAFTASEGHAHPRVVELPKTDEG---------------------------------------------------LGFNIMGGKEQNSPIYISRVIPGGVADRHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAQGSVKLVVRYTPRVLEEMEARFEKMRSARRRQQHHSYSSLESRG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88951-1", "uniprot_id": "LIN7B_MOUSE", "id": "O88951-1", "name": "Protein lin-7 homolog B", "aln": "MAALVEPLGLERDVSRAVELLERLQRSGELPPQKLQALQRVLQSRFCSAIREVYEQLYDTLDITGSAEVRAHATAKATVAAFTASEGHAHPRVVELPKTDEG---------------------------------------------------LGFNIMGGKEQNSPIYISRVIPGGVADRHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAQGSVKLVVRYTPRVLEEMEARFEKMRSARRRQQHHSYTSLESRG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HAP6-1", "uniprot_id": "LIN7B_HUMAN", "id": "Q9HAP6-1", "name": "Protein lin-7 homolog B", "aln": "MAALVEPLGLERDVSRAVELLERLQRSGELPPQKLQALQRVLQSRFCSAIREVYEQLYDTLDITGSAEIRAHATAKATVAAFTASEGHAHPRVVELPKTDEG---------------------------------------------------LGFNIMGGKEQNSPIYISRVIPGGVADRHGGLKRGDQLLSVNGVSVEGEQHEKAVELLKAAQGSVKLVVRYTPRVLEEMEARFEKMRSARRRQQHQSYSSLESRG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N6F0-1", "uniprot_id": "A0A8M1N6F0_DANRE", "id": "A0A8M1N6F0-1", "name": "Protein lin-7 homolog", "aln": "MAAMTEPLCLERDVCRVIELLDRLQRSGQLPPPKLQALQRVLQSKFCAAIREVYEQLYDTLDIIGGPEVRAQATAKATVAAFAASEGHAHPRVVELPKTDEG---------------------------------------------------LGFNIMGGKEQNSPIYISRVIPGGVADRQGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAQGSVKLVVRYTPKVLEEMEARFEKMRSARRRQQHTSYSSLESRG", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IMT8-1", "uniprot_id": "Q8IMT8_DROME", "id": "Q8IMT8-1", "name": "Protein lin-7 homolog", "aln": "MADNAEPLTLSRDVKRSIELLEKLQASGDFPTTKLAALQKVLNSDFMTSVREVYEHVYETVDIQGSHDVRASATAKATVAAFAASEGHAHPRVVELPKTEEGKTRPYELRIEGIPLYHKTNTLIVKVYRPRIYVSIIHLIWKALSIFNFCFSGLGFNVMGGKEQNSPIYISRIIPGGVADRHGGLKRGDQLLSVNGVSVEGENHEKAVELLKQAVGSVKLVVRYTPKVLEEMEMRFDKQRNTRRRQ------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** .*** *.*** * :***::** **::*. ** ***:**:* * :::*****::*:*:** *. ::** **********:****************:** ****:**************:********:********************:********* * ***********:****** **:* *.:**** ", "identical_positions": 148, "similar_positions": 30, "identity": "57.36%" }, { "cls_id": "homologset.agr.MGI:1330859", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Y231-1", "uniprot_id": "FUT9_HUMAN", "id": "Q9Y231-1", "name": "4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 9", "aln": "------------------MTSTSKGILRPFLIVCIILGCFMACLLIYI---KPTNSWIFSPMESASSVLKMKNFFSTKTDYFNETTILVWVWP-------------------------------FGQTFDLTSCQAMFNIQGCHLTTDRSLYN-----------------------------------------KSHAVLIHHRDISWDLTN------------------------------------LPQQARPP---FQKWIWMNLESPTHTPQKSGIEH-LFNLTLTYRRDSDIQVPYGFLTVSTNPFVFEVP----------------------SKEKLVCWVVSNWNPEHARVKYYNELSKSIEIHTYGQA----FGEYVNDKNLIPTISTCKFYLSFENSIHKDYITEKLYN-AFLAGSVPVVLGPSRENYENYIPADSFIHVEDYNSPSELAKYLKEVDKNNKLYLSYFNWRKDFTVNLPRFWESHACLACDHVKRHQEYKSVGNLEKWFWN-------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O88819-1", "uniprot_id": "FUT9_MOUSE", "id": "O88819-1", "name": "4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 9", "aln": "------------------MTSTSKGILRPFLIVCIILGCFMACLLIYI---KPTNSWVFSPMESASSVLKMKNFFSTKTDYFNETTILVWVWP-------------------------------FGQTFDLTSCQAMFNIQGCHLTTDRSLYN-----------------------------------------KSHAVLIHHRDISWDLTN------------------------------------LPQQARPP---FQKWIWMNLESPTHTPQKSGIEH-LFNLTLTYRRDSDIQVPYGFLTVSTNPFVFEVP----------------------SKEKLVCWVVSNWNPEHARVKYYNELSKSIEIHTYGQA----FGEYVNDKNLIPTISTCKFYLSFENSIHKDYITEKLYN-AFLAGSVPVVLGPSRENYENYIPADSFIHVEDFNSPSELAKYLKEVDKNNKLYLSYFNWRKDFTVNLPRFWESHACLACDHVKRHQEYKSVGNLEKWFWN-------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99JB3-1", "uniprot_id": "FUT9_RAT", "id": "Q99JB3-1", "name": "4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 9", "aln": "------------------MTSTSKGILRPFLIVCIILGCFVACLLIYI---KPTNSWVFSPMESASSVLKMKNFFSRKTDYFNETTILVWVWP-------------------------------FGQTFDLTSCQAMFNIQGCHLTTDRSLYN-----------------------------------------KSHAVLIHHRDISWDLTN------------------------------------LPQQARPP---FQKWIWMNLESPTHTPQKSGIEH-LFNLTLTYRRDSDIQVPYGFLTVSTSPFVFEVP----------------------SKEKLVCWVVSNWNPEHARVKYYNELSKSIEIHTYGQA----FGEYVNDKNLIPTISTCKFYLSFENSIHKDYITEKLYN-AFLAGSVPVVLGPSRENYENYIPADSFIHVEDFNSPSELAKYLKEVDKNNKLYLSYFNWRKDFTVNLPRFWESHACLACDHVKRHQEYKSVGNLEKWFWN-------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VUL9-1", "uniprot_id": "FUTA_DROME", "id": "Q9VUL9-1", "name": "Core alpha-(1,3)-fucosyltransferase", "aln": "-------------------MRRPKISLKKYFYLTLICALLLIFGFSLK---EREIWKTLSPRSSQITTQQQQHQHLHQLQSMDEEHPMATSSTPPPIAATLLPEVADNLVEEPEQTVLEEEESEADRLQEPPAEKAWFFKNGEYYPKPAKTYSNRKARKRHAPRLLPHQDPYSDRIINQLMYVPHNYEEIKSSGKLKTILLYNGLGPWNVKKGRDVFLKAKCPVDTCELTANRDLASTADMILYKDHYIPTGIRRPSNSKQVSMLYYLECPYHT-QNVKVPD-AINWTATYRRDSTIVAPYEKWQYYDTKVQQQEQDI----------------NYSVNKTKKVAWFVSNCGARNGRLQYAHELQKYIEVDIYGACGNFKCSRSTADKCFEILDNDYKFYLAFENSNCKDYITEKFFVNALNRRVLPIVMGARPEDYEVSAPRRSYIHVDEFSSPKELAEYLRILDHDDELYNSYFKWKGTGEFINTYYWCR-VCATLHNEEQLRKPRWYTDLNDWWRGPGVCTTRSWRNFKARKDVISDSSDD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P83088-1", "uniprot_id": "FUTC_DROME", "id": "P83088-1", "name": "Lewis-type alpha-(1,3)-fucosyltransferase", "aln": "MYLGRVHCSFEVPGLLSGRVGHMSMAVRSVRLACGPRGALLLLLLVLLGVLVVLHKVTQSPLLNQNKILQDHLRGQHERYIQSTRTILLWTEFFG----------------------------DSRWKLSWDTLGPQELRDELHCPVYQCEISNQN--------------------------------AFLPAVELYDAIVFHAAEMFPLLR-----------------------------------PVPSQRSP----HQVYVFALMEPPGETKHRLDDEQGFYNLTMTYRIDSDVFWPYGQLLDITADAVVAPSVKPPWRKPPVAFNDSLVWDLWSGKTKTAAWFVSHCETLSKREVLANRLQEFFEVDIYGNCGTLSCTRGDP-HCAEMLDTDYFFYLAFENSLCDDYVTEKLFD-ALERTVIPVVFGG--ADYSRILPPHSYVDANRFMSVEGLAQYMKLVVADPDLYVSYFWWRSHYRLTYSSPFCD-LCARLHDPSFGHKTQFYHDIQSWWFNSCRLQSRIRL---------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :: . :: : ** . . : : : . : . : . : : . . : ::.: : : . :* * : :* * .* :. . * * *** ** : ** .* * ..*.**: . * :.*.: :*:. ** . . : . ***:**** .**:***:: *: :*:*:* :*. * *::..: : * . **:*:: : : .** *** *: . . : * .. . :: : :::.*: . ", "identical_positions": 57, "similar_positions": 94, "identity": "10.48%" }, { "cls_id": "homologset.agr.MGI:1330860", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VFR3-1", "uniprot_id": "Q9VFR3_DROME", "id": "Q9VFR3-1", "name": "chitinase", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVRYIPLLLLG-----------------------------------------------------VLCSWPAATVASD--------------------------------------------------------QASRIVCYFSNWAVYRTGIGRYGLEDVPADLCTHIIY-SFIGVNDKSWDVLVIDPELDVDQ----GGFSKFTQLK--------------------------KSNPNVKLEIAVGGWAEGGSKYSQMVAVRDRRQSFIRSVVRFMKQYNFDGFDLDWEYPGATDRGGNYGDKDKFLYFVEELRRAFDREG-----RGWEITMAVPVAKFRLNEGYHVPELCEALDAIHAMTYDLRGNWAGFADVHSPLYKRKHDQYAY----EKLNVNDGLALWEEMGCPANKLVVGVPFYGRTFTLSNSNKN-YNMGTYINKEAGGGAPGPYTNASGFLAYYEICTEVMDKSKGWTVEWDDAGMVPYTYKDT-------QWVGYENEASIQIKMDFIKQRGYAGAMTWAIDMDDFHG-MCG-RKNGLTQILYDNMKNYRVPEPTRQTTPRPEWAKPPATPPNPDEGAVVAPTTSTTKRPKPKPKPTSSPLSPTSAPGPVPTVGSSTPKPTTKKPKKPKKTTTTTTTTPAPEKSTEEPEEVVYPVDPVEPTDPEQPMGPQFDPNEIDCTNRDFVPHPNCRKYFRCVHGKPVEFECKEGTAFHTVLNVCDWIENSDRYYCSRMKNKEKGNEAH", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8MLW8-1", "uniprot_id": "Q8MLW8_DROME", "id": "Q8MLW8-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTSFQYVFMIMIF-----------------------------------------------------LICGCIAKEYN--------------------------------------------------------------VFCQYDLGSYYYKGRSQFFEWHLDSRLCTHLVLGSGIGVDGDSGELRITDKILLLEK----DKLSSVKTMK--------------------------WDS-IKKVMFTIGGWEEDSSSFSRMVASPKKRDNFYSSMLEFMFRWGFDGVQIDWRYP--TLLGGHPDDRQNFVILLEELGLIFRKN------QLILMVAVLGRRDNRILESYNIPEIVNHSDFIHLMMHDEQDPYHLRLAYNAPLVGYEG------------SVTDSIMHWKRNGGAPEKLILGIPLFVRSFTMDR------NQSTVGSACKGPGRQTKQSHRPGFMTYNEWCVQQSK----WSRMFDQLAKVPYATRGD-------QWVSYENPRSIWAKMHLLQEHKLGGAMAWTIDVDDFRG-RCG-EQHGLLRVIFSALG-----DKNGLTTEKP----------------------------------------TTEASGLCPHDGFSRDGWDCR---------------------------LYHECRDGERIYYECLEGQYFDENQIVCR-------------------PAAEVKCDQ--------NFVIWRPGMPVYSYDNMPLNLKIVE--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W2M6-1", "uniprot_id": "Q9W2M6_DROME", "id": "Q9W2M6-1", "name": "chitinase", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKLVSIWAL-----------------------------------------------------AALCLCLGQVAS---------------------------------------------------------SEKLLNCYWGTWANYRPGDGKFTPSDIDPSLCTHISY-TFFGIS-DAGEFKSLDTWLDMDD--GLGFISQTIALK--------------------------QRNPNLKILAVVGGWNEGSTKYSAMAADPAKRATFVSTSLAFIQQYSFDGLDLDWEYPG-QRGGSEA-DRENFVTLLREIKETYDQY-------GLELGIAVGASEKSASISYDIPAISQHLTFINVMTYDFHMALDGYLGLNAPLPEVAESID----------------YWLSHGAPAEKLILGIGFYGHSYQMSDS-----SQNWPGAACIGPGTAGVYTRENGFLGYHEICLNN------WQTVFDQENGAPYAFQGD-------QWIGYDNPESIQLKMQLVESRNLGGAMMWSIETDDFRG-LCG-ESYPLLKTMNRALGREVSGGSGGGGGGGGEGSVTPAPTAAP---------------------------TSSPTPAPTPGGGSGGNECAQDG-----------------FFVLESDCNKFYQCVGGVRYDFQCGAGLCFNTITLNCD-------------------WP------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W2M5-1", "uniprot_id": "Q9W2M5_DROME", "id": "Q9W2M5-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGKLLAL-----------------------------------------------------LAV-LCLSQVIG---------------------------------------------------------AERIVNCYWGTWANYRSGNGKFDVSNIDAGLCTHLSY-SFFGIN-DNGEIQSLDTWLDYD----LGFINQAISLK--------------------------NQNSNLKVLAVVGGWNEGSTKYSSMSGDWYKRQNFINSALNLLRNHGFDGLDLDWEYPN-QRGGNWN-DRANFVTLLREIKEAFAPY-------GYELGIAVGAGESLASASYEIANIAQQVDFINVMTYDFAMASDGQTGFNAPQWAVENAIN----------------FWLSQGAPANKLVLGVGTYGRSFQLSDS-----SQNWPGAPCRGEGSAGSYTGSTGYLGYNEICQNN------WHTVFDYDNAAPYAYSGD-------QWVSFDNVLSVQYKMDFALSKGLAGAMIWSLETDDYRG-QCG-ETYPLLKTINRKLRW--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W2M7-1", "uniprot_id": "Q9W2M7_DROME", "id": "Q9W2M7-1", "name": "chitinase", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MWSVSGLVKLLLG-----------------------------------------------------VILMAASSSAQGN--------------------------------------------------------SSKNVVCYQGTWSVYRPGLGKFGMEDIDPFLCTHLIY-AFLGIE-ETGQLRVIDAYLDLEENSGRGNIKSFNALK--------------------------LKNPVLKTLVAVGGWNEGSKRFSLVARDPSKREKFVDDVVRFLQRHGFDGLDLDWEYPG-QRHSLDNEDRSNYITFLKELKEGLEPF-------GFILSAAVGSAQFSAEISYDIPAMVPYLDLINVMAYDLHGPWDQVVGINAPLYAAEKDASDSSGRQQQLNVDAVVKYWLKAGAPAEKLILGVPFYGRSFTLATA-----EGNQPGAPHIGKGIAGNYSREPGVLGYNELCEMMEREE--WTQKWEATQQVPYAYRQR-------QWVGYEDPRSLALKAQYVMDNHLGGIMIWSLESDDFRG-TCGQQPYPLLHEINRVLFG--------------------GNTPSG---------------------------LTTESNRESPSEGFSCPADAPAG-----------------YIRDPDNCSKFYYCSGGKTHNFDCPSGLNFDLDTKSCN-------------------YSGSVKC-------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "O35744-1", "uniprot_id": "CHIL3_MOUSE", "id": "O35744-1", "name": "Chitinase-like protein 3", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAKLILVTG------------------------------------------------------LAILLNVQLG----------------------------------------------------------SSYQLMCYYTSWAKDRPIEGSFKPGNIDPCLCTHLIY-AFAGMQNNEITYTHEQDLRDYEA---------LNGLK--------------------------DKNTELKTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQYNFDGLNLDWQYPG--SRGSPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGIIDVIKSGYKIPELSQSLDYIQVMTYDLHDPKDGYTGENSPLYKSPYDIGKS----ADLNVDSIISYWKDHGAASEKLIVGFPAYGHTFILSDP-----SKTGIGAPTISTGPPGKYTDESGLLAYYEVCTFLNEG---ATEVWDAPQEVPYAYQGN-------EWVGYDNVRSFKLKAQWLKDNNLGGAVVWPLDMDDFSGSFCHQRHFPLTSTLKGDLN-------------------------------------------------------IHSASCKGPY----------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1M559-1", "uniprot_id": "F1M559_RAT", "id": "F1M559-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAKLILATG------------------------------------------------------LAILLYAHLG----------------------------------------------------------SSYQLMCYYTSWAKDRPTVGSFKIGNIDPCLCTHLIY-AFAGMRNNEIINTSEQDLIDYEA---------INYLK--------------------------DRNTELKTLLAIGGWKFGSAPFSAMVSTPQNRQTFIKSVIKFLRQYKFDGLNLDWQYPG--SRGSPPKDKHLFSVLVQEMRKAFEKESTEQEIPRLLLTATVAGVIDTIQSGYKIPELSQSLDYFQVMTYNLHDFQNGYTRENSPLYQSPSDTGIY----AYLNVDAIISYWKDNGAAREKLIVGFPAYGHNFILSDP-----SNTGINAPIVSTGPPGKFTGEAGLWAYYEICTFLNDG---ATDLWDGPQEVPYAVQGN-------VWVGYDNVKSFKIKAQWLKDNKLGGAMVWPLDMDDFTGSFCQQGRFPLTSTLKHYLG-------------------------------------------------------VQSTNCMAYKEEL-------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BZP6-1", "uniprot_id": "CHIA_HUMAN", "id": "Q9BZP6-1", "name": "Acidic mammalian chitinase", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTKLILLTG------------------------------------------------------LVLILNLQLG----------------------------------------------------------SAYQLTCYFTNWAQYRPGLGRFMPDNIDPCLCTHLIY-AFAGRQNNEITTIEWNDVTLYQA---------FNGLK--------------------------NKNSQLKTLLAIGGWNFGTAPFTAMVSTPENRQTFITSVIKFLRQYEFDGLDFDWEYPG--SRGSPPQDKHLFTVLVQEMREAFEQEAKQINKPRLMVTAAVAAGISNIQSGYEIPQLSQYLDYIHVMTYDLHGSWEGYTGENSPLYKYPTDTGSN----AYLNVDYVMNYWKDNGAPAEKLIVGFPTYGHNFILSNP-----SNTGIGAPTSGAGPAGPYAKESGIWAYYEICTFLKNG---ATQGWDAPQEVPYAYQGN-------VWVGYDNIKSFDIKAQWLKHNKFGGAMVWAIDLDDFTGTFCNQGKFPLISTLKKALG-------------------------------------------------------LQSASCTAPAQPIEPITAAPSG-------------------------------SGNGSGSSSSGGSSGGSGFCAVRANGLYPVANNRNAFWHCVNGVTYQQNCQAGLVFDTSCDCCNWA---------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VZV2-1", "uniprot_id": "Q9VZV2_DROME", "id": "Q9VZV2-1", "name": "", "aln": "MFPPRLLRIAFVICLLIVLLSPSADSAQTKTRRRLRRPTTSVSSSRSNLIESKKSTEAPEAEKRIDQITSATTTSARRTRLRSKAKLGAAAAGGAAVAAGGTALVASGSSLKGKKTKVDDGTPKIVCYYTNWSQYRVKIGKFVPEDIPADLCTHIIFAFGWLKKNKLSSYESNDETKDNVPGLYERMMTLKKANPKLKILLALGGWSFGTQKFKDMSSTRYTRQTFVYSAIPFLRKRGFDGLDMDWEYPKGSDDKKNFVLLLKELREAFEAEAQELKKPRLLLSAAVPVGPDNIRGGYDVPAIASYLDFINLMAYDFHGKWERETGHNAPLYAPSTDSEWRKQLSVDNAASLWVKMGAPKEKLVIGMPTYGRSFTLANPDKHGPNAPASGGGREGVYTKEGGFLAYYEICEMLLNGAVYVWDDEMKVPYLVDGDQWVGFDDERAIRNKMHWIKSNGFGGAMVWTIDMDDFKGEVCGGNVKYPLIGAMREELLGISRGKEAKDVNWTAVAATFEDIEEKPEPIKISVDEILNKVRKPQVQKKQRIKSGANAVASNTRPAQVFCYLTSWSAKRPGAGKFQPENIDPKLCTHIVY-AFATLQDYKLTEATDDDPENYES---------VIALR--------------------------DNNPDLQILLAIGGWAFGSTPFKELTSNVFRMNQFVYEAIDFLRDYKFNGLDVDWEYP----RG--AEDRVAYVSLLKELRVAFEGEAKSSGLPRLLLTAAVPASFEAIAAGYDVPEISKYLDFINVMTYDFHGQWERTVGHNSPLFALESATGYQ----KKLTVDYSAREWVKQGAPKEKLLIGMPTYGRSFELVND-----TQFDIGSPSSGGGKAGKFTNEAGFLSYYEVCSFLAADN--TTLVWDSEQQVPFAYRGN-------QWVGFDDERSLKTKTEWLKEQGFGGIMVWSIDMDDFSG-RCGSGKYPLLTALNDELKDY-----------------------------------------------------KVELEYDGPYESHGPRGAYTTK-------------------------------DPHDVTCAEEDGHISYHKDWADCT-----------HYYMCEGERKHHMPCPANLVFNPQENVCDWPENVEGCHTPTEAPA-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W092-1", "uniprot_id": "CHIT2_DROME", "id": "Q9W092-1", "name": "Probable chitinase 2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTLRSRLSGEAPQLWLLLLLAS-----------------------------------------------------TASSLWASVAARTG-----------------------------------------------------PLHDKVVVCYVSTWAVYRPEQGAYAIENFDPNLCTHVVY-AFAGLDITQAAIKSLDPWQDLKEEYGKGGYEKMTGLK--------------------------RSHPHLKVSLAIGGWNEGSANYSTLVANNLLRGRFVKQVSSFIRKYNFDGLDLDWEYPT--QRKGKPADRENFVLLTKELREEFDEHG-------LLLTSAIGASKKVIDEAYDVRQISRYLDYLHIMCYDYHGSWDRRVGYNAPLTAPADDP---------LSVKFSIDYLLKLGAPPEKLVMGLPFYGRTFKTLAS-------GFLNDVSEGVGFKGPYTREDGFLGYNEICQTLSNQTSGWTREWDPQTSQVLAKSERNVFTQEINVVTYDSSRSIANKVLFAMSKRLAGVMVWSVDTDDFLG-NCKLDEDTYEDFQKVTAAP-----------------------------------------------------KRSSQNYPLLRTINEATMLAVD--------------------------ELAVPEPQPDDSENEIPHGSIADRKNAGAS--------------------MVSLGLGVTAVFMLLHRLAQ-----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06350-1", "uniprot_id": "CHI2_YEAST", "id": "Q06350-1", "name": "Sporulation-specific chitinase 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVGHSAQHRSKSSLVSHLLILLIFIT-----------------------------------------------IIIEMCLYNKIFKNQRSDDIRDNFNNGGHRVPSNVQNHG-------------------------------THIRDEAFISGVYYSNWSPYKPR--FHFPHDINLKQVSHIYY-AFFKINSRTGGIENTDSWSDLEMNLYKSLAIKNSELIKESSNNSVQNILPLGCIGELFYLKNTCSDKKFKVIMSIGGWS-DSENFKIIIKDDKLLQNFVDSSVETMFRLGFDGIDLDWEFPG--NNESEPRGYLKLVRMLRLKLNSLESQIFGKRTEDHFQLSIAAPAFKDKLFYLPITEIDQYVDYWNMMTYDYYGSWSETTGYHSNLFSETELNG----------NFAMHYMIDRFGVNSRKLVLGMAAYGRSFHIKDNKFEPFNQNTVLINKIFKGVGKPTKEIDKADGKEGIWPYKNLPKIGTIEQYDPKYVSAYCFDEKNS-----IFISYDNTKSVKTKAEYVTHNNLGGGFWWESCGEAYAN-----ESRSLINAFNEGLHFN-----------------------------------------------------VSSKPSIFQDVRVKKYYLNKYG-----------------------------------DGGFLSPYLKHLDSRKQ------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . .. :*: : : . : : :*** . :. : * : *:*.:.**.:* . : . : : : * :: :: * .**::*. : :.: * :: : ::. *. * . .* . * : : . ", "identical_positions": 20, "similar_positions": 55, "identity": "1.7%" }, { "cls_id": "homologset.agr.MGI:1330861", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O15075-1", "uniprot_id": "DCLK1_HUMAN", "id": "O15075-1", "name": "Serine/threonine-protein kinase DCLK1", "aln": "----------------------------------------------------------------------------------------------------MSFGRDMELEHFDERDKAQRYSRGS-RVNGLPSPTHSAHCSFYRTRTLQTLSSEKKAKKVRFYRNGDRYFKGIVYAISPDRFRSFEALLADLTRTLSDNVNLPQGVRTIYTIDGLKKISSLDQLVEGESYVCGS-IEPFKKLEYTKNVN-------PNWSVNVKTTSASRAVSSLAT-------------------AKGSPSEVRENKDFIRPKLVTIIRSGVKPRKAVRILLNKKTAHSFEQVLTDITDAIKLDSGVVKRLYTLDGKQVMCLQDFFGDDDIFIACGPEKFRYQDDFLLDESECRVVKSTSYTKIASSSRRSTTKSPGPSRRSKSPASTSSVNGTPGSQLSTPRSGKSPSPSPTSPGSLRKQRSSQHGGSSTSLASTKVCS-SMDENDGPGE----------------EVSEEG--FQIPATITERYKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRVKHPNIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNIVHRDIKPENLLVYEHQDG-SKSLKLGDFGLATIVDGPLYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELITMMLLVDVDQRFSAVQVLEHPWVNDDGLPENEHQLSVAGKIKKHFNTGPKPNSTAAGVSVIATTALDKERQVFRRRRNQDVRS----------------------------RYKAQPAPPELN-----------SESEDYSPSSSETVRSPNSPF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9JLM8-1", "uniprot_id": "DCLK1_MOUSE", "id": "Q9JLM8-1", "name": "Serine/threonine-protein kinase DCLK1", "aln": "----------------------------------------------------------------------------------------------------MSFGRDMELEHFDERDKAQRYSRGS-RVNGLPSPTHSAHCSFYRTRTLQTLSSEKKAKKVRFYRNGDRYFKGIVYAISPDRFRSFEALLADLTRTLSDNVNLPQGVRTIYTIDGLKKISSLDQLVEGESYVCGS-IEPFKKLEYTKNVN-------PNWSVNVKTTSASRAVSSLAT-------------------AKGGPSEVRENKDFIRPKLVTIIRSGVKPRKAVRILLNKKTAHSFEQVLTDITDAIKLDSGVVKRLYTLDGKQVMCLQDFFGDDDIFIACGPEKFRYQDDFLLDESECRVVKSTSYTKIASASRRGTTKSPGPSRRSKSPASTSSVNGTPGSQLSTPRSGKSPSPSPTSPGSLRKQRISQHGGSSTSLSSTKVCS-SMDENDGPGEGDELGRRHSLQRGWRREESEEG--FQIPATITERYKVGRTIGDGNFAVVKECIERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRVKHPNIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTSKYTERDASGMLYNLASAIKYLHSLNIVHRDIKPENLLVYEHQDG-SKSLKLGDFGLATIVDGPLYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELINMMLLVNVDQRFSAVQVLEHPWVNDDGLPENEHQLSVAGKIKKHFNTGPKPSSTAAGVSVIATTALDKERQVFRRRRNQDVRS----------------------------RYKAQPAPPELN-----------SESEDYSPSSSETVRSPNSPF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O08875-1", "uniprot_id": "DCLK1_RAT", "id": "O08875-1", "name": "Serine/threonine-protein kinase DCLK1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLELIEVNGTPGSQLSTPRSGKSPSPSPTSPGSLRKQRISQHGGSSTSLSSTKVCS-SMDENDGPGE----------------EESDEG--FQIPATITERYKVGRTIGDGNFAVVKECIERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRVKHPNIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTSKYTERDASGMLYNLASAIKYLHSLNIVHRDIKPENLLVYEHQDG-SKSLKLGDFGLATIVDGPLYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELINMMLLVNVDQRFSAVQVLEHPWVNDDGLPENEHQLSVAGKIKKHFNTGPKPSSTAAGVSVIATTALDKERQVFRRRRNQDVRG----------------------------RYKAQPAPPELN-----------SESEDYSPSSSETVRSPNSPF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ACD6B5Y1-1", "uniprot_id": "A0ACD6B5Y1_DANRE", "id": "A0ACD6B5Y1-1", "name": "Serine/threonine-protein kinase DCLK2", "aln": "-----------------------------------------------------------------------------------------------------------MEEHFDERDKLQRNSRSAGRANGLLSPTHSAHCSLYRTRTLKTLSSEKKAKKVRFYRNGDRYFNGIVYAISSDRIRTFDALLADLTRTLSDNVNLPQGVRIIYSIDGNKKITNIDQLVEGESYVCGS-TEAFKRVDYSNNVN-------PNWSVNVRALGSSKCPTSLAS-------------------SKSGP-QFRESKDFIRPKLVTVIRSGVKPRKAVRILLNKKTAHSFEQVLTDITDAIKLDSGIVKRIYTLEGKQVSCLQDFFGEEDIFIACGPEKFRYQDDFLLDESECRVVKSTSYGKVGSLNRNSP-RSVVLCRRSKSPSG--SVNGTPASQLSTPHSPKSPSPSPASPGSLKKRRGSQHSGSSLSLASTKVCS--MDEEEGPVS--------------DAETLEETPIPTVPSSISDRYKVGRMIGDGNFAVVHECVEHSTDRAYALKIINKGKCRGKEHMIQNEVAILRRVKHPNIVLLIEEMDTYNELYLVMELVKGGDLFDAITSANRYTERDASGMLYNLASAIKYLHSLNIVHRDIKPENLLVYEHQDG-SKSLKLGDFGLATVVDGPLYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCGFPPFRGSTEDQEALFDQILLGQLEFPLPYWDNVSDSAKELIVSMLQVEVDQRYTALQVLEHPWVTNDGLSENEHQLSVAGKIKKHFNTGPKPN--TPGVTVMTTTALDKERQILRRGRHQNVSAALWITQPTCSLHIPAFTPHLCPSLHLQPSFPMGPPAPALVPSLCPATATSTPESEDFSACSTETVRSLFSPF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7PLI7-1", "uniprot_id": "DCLK_DROME", "id": "Q7PLI7-1", "name": "Serine/threonine-protein kinase CG17528", "aln": "MELEKVKINSLHCNDAVLSSLQASPSATSPQSVPSKANVVTEASIIEKTNQPHNVQEDNNYNRDCDSPESSSSEQDKELDDLRNLHSSSLTNSVVVGKSTGSLNGVYSITSVTSETKTLESVVTTNSASGSACLSNTPTADHIKKRIPSSRTPTRKALRIKFYRNGDRFYPGITIPVSNERYRSFERLFEDLTRLLEENVKIPGAVRTIYNLCG-KKITSLDELEDGQSYVCSCNNENFKKVEYNTGSQPLSNLPLSNSRSNSHRLAKCRPSSPLKNGLLAGSSPFPACGGGTGNGSPLIASRLSDRVTVVHPRIVTLIRSGTKPRRIMRLLLNKRNSPSFDHVLTAITQVVRLDTGYVRKVFTLSGIPVVRLSDFFGSDDVFFAYGTERINTAEDFKLEAEEQRAIN------------------------VIRKTMRTTGTTCKGPKPKMPIKSKKVYPPLVDSEPFKAETTPEDDRHAALLTSTGMEIN-----------------------------------ELPSNIRNTYSLGRIIGDGNFAIVFKIKHRQTGHSYALKIIDKNKCKGKEHYIDAEVRVMKKLNHPHIISLILSVDQNTNMYLVLEYVSGGDLFDAITQVTRFSENQSRIMIRHLGAAMTYLHSMGIVHRDIKPENLLVKLDEHGNVLELKLADFGLACEVNDLLYAVCGTPTYVAPEILLEVGYGLKIDVWAAGIILYILLCGFPPFVAPDNQQEPLFDAIISGIYEFPDPYWSDIGDGVRDLIANMLQADPDVRFTSEDILDHSWTIGN---------------------------------------KGNECTTYKR--------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . ..: . * . *. *. ... .:: . .:.. : *:** : :*:.* : *.:** *******:* : .:.* : ******.*.**:**** *: ** ::::::**:*: ** .:* .::***:* *.*********...:::*.:: *: :*.:*:.****:.************* .:.* .***.***** *:. **:************: *.*****:*:****:* ********** .. ::** *** *: * :** ***.::.*..::** ** .: * *::: ::*:*.*. .: .:* :* ", "identical_positions": 147, "similar_positions": 112, "identity": "15.86%" }, { "cls_id": "homologset.agr.MGI:1332225", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P33579-1", "uniprot_id": "PR8A5_RAT", "id": "P33579-1", "name": "Prolactin-8A5", "aln": "-MELALSQPSFFGTLLMLVVSNLLLWEKAASIPACMVEDGGCWDPLREAFNSATQRAETLRNLSDQLYVEFFQNQFSSRQFADLSSQLIRKDETVLKAGTYCHSNRAK-PKSRGV--NIDIEEYLKMSINFCGFMDQPLFHLVIELSAMEGVPETILSKAKDLEENNRQLLDDLRWILTKVFPTAEIKEEFPSWDYLSFLKSSNKNHKFLAIFNLSSCLDYDTQVHYTLSQILNCLITGKDC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P33580-1", "uniprot_id": "PR8A4_RAT", "id": "P33580-1", "name": "Prolactin-8A4", "aln": "MMKLALSQPPFSGTLLMLVVSILLLWEKAASIPACMVEEGDCWDPLQETFNSAIQRAETLCNLADQLYVEFYQNQFSSRQFADLNSKLIKRDETVLKAGIYCHSTLAK-PQTRGG--NFEIEEHLKMLINFVGSWISPLFHLVIELSAMEGVPETILCKVKDLEENNRQLLDDLRWILTKVSPTAEIREEFPSWEHLSFLKSSNKNNKFLAMFNLSNCLDNDTKFTLHHLRIFKCLITGKDC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DAY2-1", "uniprot_id": "PR8A6_MOUSE", "id": "Q9DAY2-1", "name": "Prolactin-8A6", "aln": "-MALLLSQPHFSGPLLLLVVSNLLLWEKAASNLPCVAEEGGCWNPLLETFNSATQKAETLHNLADQLYVELYYNQFSSGQFWDFSSQIIRQDKTVVRAGSYCHSSLTN-PPNTGVHINIEIASYLKTLINFVGSWISPLFHLVIELSATKDVPETILSKAKEIEENNRQILSDLRWILTKVSPAAEMTEEFPHWEYLSFLKSSDKNNKFLAMFNLSYCIDHDSKYILLQLRLLKCLITGKDC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P33578-1", "uniprot_id": "PR8A7_RAT", "id": "P33578-1", "name": "Prolactin-8A7", "aln": "-MELPLSQHSFC-KLLLLVVSSLLLWEKAASIPACLAEEGGCWNPLVETFNSAIHKAETLYDLANQIHVELYQNKFSSEQFSSLNSQVIRKDKTALRAGSYCHSTLINTPNKENEHINIEIKEYVKTLINFVGAWISPLYHLVLELSAMQDVPESILSKAKEIEENNRQLLDDLKWILIKVSPTEEMKEEFPSWGHLSFLKSSGEKSKFLAMFNLSNCLGYDAKYTLLNLRILKCLTTGKDC", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * *** * **:**** ********* .*:.*:*.**:** *:**** ::**** :*::*::**:: *:*** ** .:.*::*::*:*.::** ****. : * . . *::* .::* *** * .**:***:**** :.***:**.*.*::******:*.**:*** ** *: *: **** * :*******.:: ****:**** *:. *:: ::::** *****", "identical_positions": 126, "similar_positions": 66, "identity": "52.07%" }, { "cls_id": "homologset.agr.MGI:1332226", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7TQM4-1", "uniprot_id": "SOAT2_RAT", "id": "Q7TQM4-1", "name": "Sterol O-acyltransferase 2", "aln": "------MEPKAPQLR--RRERQGEEQENGACG------------EGNTRTHRAPDLVQWTRHMEAVKTQCLEQAQRELAELMDRAIWEAVQAYPKQDRP-LPSTASDS-----TRKTQELHPGKRKVFITRKSLLDELMGV-----------------------------------------------------------------------QHFRTIYHMFIAGLCVLIISTLAIDFIDEGRLMLEFDLLLFSFGQLPLALMMWVPMFLSTLLLP-YQTLRLWARPRSGGAWTLGASLG--CVLLAAHAAVLCVLPVHVSVKHELPPASRCVLVFEQVRFLMKSYSF-LRETVPGIFC--VRGGKGIC---------------------------------TPSFSSYLYFLFCPTLIYRETYPRTPSIRWNYVAKNFAQALGCLLYACFILGRLCVPVFANMSREPFS--------TRALLLSILHATGPG-IFMLLLIFFAFLHCWLNAFAEMLRFGDRMFYRDWWNSTSFSNYYRTWNVVVHDWLYSYVYQDGLWLLGRQGRGAAMLGVFLVSALVHEYIFCFVLG--FFYPVMLILFLVVGGLLNFTMNDRHTGPAWNILMWTFLFLGQGIQVSLYCQEWYARRHCPLPQPTFWELVTPRSWSCHP-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88908-1", "uniprot_id": "SOAT2_MOUSE", "id": "O88908-1", "name": "Sterol O-acyltransferase 2", "aln": "------MQPKVPQLR--RREGLGEEQEKGARGG-----------EGNARTHGTPDLVQWTRHMEAVKTQFLEQAQRELAELLDRALWEAMQAYPKQDRP-LPSAAPDS-----TSKTQELHPGKRKVFITRKSLIDELMEV-----------------------------------------------------------------------QHFRTIYHMFIAGLCVLIISTLAIDFIDEGRLMLEFDLLLFSFGQLPLALMTWVPMFLSTLLVP-YQTLWLWARPRAGGAWMLGASLG--CVLLAAHAVVLCVLPVHVSVRHELPPASRCVLVFEQVRLLMKSYSF-LRETVPGIFC--VRGGKGIS---------------------------------PPSFSSYLYFLFCPTLIYRETYPRTPSIRWNYVAKNFAQVLGCLLYACFILGRLCVPVFANMSREPFS--------TRALLLSILHATGPG-IFMLLLIFFAFLHCWLNAFAEMLRFGDRMFYRDWWNSTSFSNYYRTWNVVVHDWLYSYVYQDGLWLLGRRARGVAMLGVFLVSAVVHEYIFCFVLG--FFYPVMLMLFLVFGGLLNFTMNDRHTGPAWNILMWTFLFMGQGIQVSLYCQEWYARRHCPLPQTTFWGMVTPRSWSCHP-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75908-1", "uniprot_id": "SOAT2_HUMAN", "id": "O75908-1", "name": "Sterol O-acyltransferase 2", "aln": "------MEPGGARLRLQRTEGLGGERERQPCG------------DGNTETHRAPDLVQWTRHMEAVKAQLLEQAQGQLRELLDRAMREAIQSYPSQDKP-LPPPPPGS-----LSRTQEPSLGKQKVFIIRKSLLDELMEV-----------------------------------------------------------------------QHFRTIYHMFIAGLCVFIISTLAIDFIDEGRLLLEFDLLIFSFGQLPLALVTWVPMFLSTLLAP-YQALRLWAR----GTWTQATGLG--CALLAAHAVVLCALPVHVAVEHQLPPASRCVLVFEQVRFLMKSYSF-LREAVPGTLR--ARRGEGIQ---------------------------------APSFSSYLYFLFCPTLIYRETYPRTPYVRWNYVAKNFAQALGCVLYACFILGRLCVPVFANMSREPFS--------TRALVLSILHATLPG-IFMLLLIFFAFLHCWLNAFAEMLRFGDRMFYRDWWNSTSFSNYYRTWNVVVHDWLYSYVYQDGLRLLGARARGVAMLGVFLVSAVAHEYIFCFVLG--FFYPVMLILFLVIGGMLNFMMHDQRTGPAWNVLMWTMLFLGQGIQVSLYCQEWYARRHCPLPQATFWGLVTPRSWSCHT-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13A9C6-1", "uniprot_id": "A0AB13A9C6_DANRE", "id": "A0AB13A9C6-1", "name": "O-acyltransferase", "aln": "------MSKVQMVVRRFAGQTSGENQRCSENGSF----------PQNENGRNITEAAHRKDDMERLKAELIRRVQTQLNDAVERAVSDSITSLNTHSHTNMLTHTDNK-----TSSGDRHKLDQGKVFVARCSLLDELFEI-----------------------------------------------------------------------SHIRTIYHMFIAALFLFFMSTLAVDYIDQGRLVLDLGLFYYAFGQLHVVICCWTLMFSYTLLGP-YHVLRVWAGLYHNGHHRTCVCVITAIILCAAQMSMLGIFPVYVVLHYQLPPASRFIIILEQIRFVMKSYSF-IRESTAAALKNTPQKGERLW---------------------------------FPALSSYLYFLFCPTLIYREVYPRNPNIRWRFVGMNFLKVLASLFYLYFILERLCIPVFRNKSGLQFS--------TRTLILTLFHAAFPG-MLMLMLGFYAFLHCWLNAFAEMLRFADRMFYKDWWNSTSFANYYRTWNIVVHDWLYYYAYRDFLWLSGYKLRSVATLSVFAVSALVHEYAFTMGFG--FFYPVMFCTFAGIGVVFNFAMNDKRKSPVWNIIMWTCLFIGQGVHVCLYCLEWYAQIHCPRTGAGFWDLVTPRSWTCSYQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P53629-1", "uniprot_id": "ARE2_YEAST", "id": "P53629-1", "name": "Sterol O-acyltransferase 2", "aln": "MDKKKDLLENEQFLRIQKLNAADAGKRQSITVDDEGELYGLDTSGNSPANEHTATTITQNHSVVASNGDVAFIPGTATEGNTEIVTEEVIETDDNMFKTHVKTLSSKEKARYRQGSSNFISYFDDMSFEHRPSILDGSVNEPFKTKFVGPTLEKEIRRREKELMAMRKNLHHRKSSPDAVDSVGKNDGAAPTTVPTAATSETVVTVETTIISSNFSGLYVAFWMAIAFGAVKALIDYYYQHNGSFKDSEILKFMTTNLFTVASVDLLMYLSTYFVVGIQYLCKWGVLKWGTTGWIFTSIYEFLFVIFYMYLTENILKLHWLSKIFLFLHSLVLLMKMHSFAFYNGYLWGIKEELQFSKSALAKYKDSINDPKVIGALEKSCEFCSFELSSQSLSDQTQKFPNNISAKSFFWFTMFPTLIYQIEYPRTKEIRWSYVLEKICAIFGTIFLMMIDAQILMYPVAMRALAVRNS-EWTGILDRLLKWVGLLVDIVPGFIVMYILDFYLIWDAILNCVAELTRFGDRYFYGDWWNCVSWADFSRIWNIPVHKFLLRHVYHSSMSSFKLN-KSQATLMTFFLSSVVHELAMYVIFKKLRFYLFFFQMLQMPLVALTNTKFMRNRTIIGNVIFWLGICMGPSVMCTLYLTF----------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P25628-1", "uniprot_id": "ARE1_YEAST", "id": "P25628-1", "name": "Sterol O-acyltransferase 1", "aln": "MTETKDLLQDEEFLKIRRLNSAEANKRHSVTYDN--VILPQESMEVSPR----SSTTSLVEPVESTEG-VESTEAERVAGKQEQEEEYPVDAHMQKYLSHLKSKSRSR--FHRKDASKYVSFFGDVSFDPRPTLLDSAINVPFQTTFKGPVLEKQL-----------KNLQLTKT---------KTKATVKTTVKTTEKTDKADAPPGEKLESNFSGIYVFAWMFLGWIAIRCCTDYYASYGSAWNKLEIVQYMTTDLFTIAMLDLAMFLCTFFVVFVHWLVKKRIINWKWTGFVAVSIFELAFIPVTFPIYVYYFDFNWVTRIFLFLHSVVFVMKSHSFAFYNGYLWDIKQELEYSSKQLQKYKESLS-PETREILQKSCDFCLFELNYQTKDND---FPNNISCSNFFMFCLFPVLVYQINYPRTSRIRWRYVLEKVCAIIGTIFLMMVTAQFFMHPVAMRCIQFHNTPTFGGWIPATQEWFHLLFDMIPGFTVLYMLTFYMIWDALLNCVAELTRFADRYFYGDWWNCVSFEEFSRIWNVPVHKFLLRHVYHSSMGALHLS-KSQATLFTFFLSAVFHEMAMFAIFRRVRGYLFMFQLSQFVWTALSNTKFLRARPQLSNVVFSFGVCSGPSIIMTLYLTL----------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: : :. . . : : : : : . : . . . * * :::* . .:: :* : : : . . . :. : :* *: * : : * . : : : . . * * .:: : . :.* : ::: : . : : ..:: * : *.*:*: ***. :** :* :. :. :: . : ** . : . :: ** .: :* *: : .. **..**: **.** ** ****..*: :: * **: **.:* :.*:. : :. * * .* :*:: ** : : * .:: :. : *::: : * .: ** ", "identical_positions": 60, "similar_positions": 128, "identity": "8.93%" }, { "cls_id": "homologset.agr.MGI:1332234", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62806-1", "uniprot_id": "ZN148_RAT", "id": "Q62806-1", "name": "Zinc finger protein 148", "aln": "MNIDDKLEGLFLKCGGIDEMQSSRAMVVMGGVSGQSAVSGELQESVLQDRSLPHQEILAADEVLQESE-----------MRQQDMISHDELMVHEETVKND-EEQTDTHERLPQGLQYALNVPISVKQEITFTDVSEQLMRDKKQVREPVDLQKKKKRKQRSPAKILTINEDGSLGLKTPKSHVCEHCNAAFRTNYHLQRHVFIHTGEKPFQCSQCDMRFIQKYLLQRHEKIHTGEKPFRCDECGMRFIQKYHMERHKRTHSGEKPYQCEYCLQYFSRTDRVLKHKRMCHENHDKKLNRCAIKGGLLTSEEDSGFSTSPKDNSLPKKKRQKPEKKS------SGMDKESVLDKSDTKKD---RNDYLPLYSSSTKVKDEYMVAEYAVEMPHSSVGGSHLEDASG---EIHPPKLVLKKINSKRSLKQP-LEQSQTISPLSTYEDSKVSKYAFELVDKQALLDSEGSADIDQVDNLQEGPSKPVHSSTNYDDAMQFLKKKRYLQAASNN-SREYALNVGTIASQPSVTQAAVASVIDENTTASIL-DSQALNVEIKSNHDKNVIPDEVLQTLLDHYSHKANGQHEISFSVADTEVTSSISINSSDVPEVTQSENVGSSSQASSSDKANMLQEYSKFLQQALDRTSQNDAYLNSPSLNFVTDNQTLPNPPAFSSIDKQVYAAMPINSFRSGMNSPLRTTPDKSHFGLIVGDSQHPFPFSGDETNHASATSTADFLDQVTSQKKAEAQPVHQAYQMSSFEQPFRAPYHGSRAGIATQFSTANGQVNLRGPGTSAEFSEFPLVNVNDNRAGMTSSPDATTGQTFG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61624-1", "uniprot_id": "ZN148_MOUSE", "id": "Q61624-1", "name": "Zinc finger protein 148", "aln": "MNIDDKLEGLFLKCGGIDEMQSSRAMVVMGGVSGQSAVSGELQESVLQDRSLPHQEILAADEVLQESE-----------MRQQDMISHDELMVHEETVKND-EEQMDTHERLPQGLQYALNVPISVKQEITFTDVSEQLMRDKKQVREPVDLQKKKKRKQRSPAKILTINEDGSLGLKTPKSHVCEHCNAAFRTNYHLQRHVFIHTGEKPFQCSQCDMRFIQKYLLQRHEKIHTGEKPFRCDECGMRFIQKYHMERHKRTHSGEKPYQCEYCLQYFSRTDRVLKHKRMCHENHDKKLNRCAIKGGLLTSEEDSGFSTSPKDNSLPKKKRQKTEKKS------SGMDKESVLDKSDLKKD---KNDYLPLYSSSTKVKDEYMVAEYAVEMPHSSVGGSHLEDASG---EIHPPKLVLKKINSKRSLKQP-LEQSQTISPLSSYEDSKVSKYAFELVDKQALLDSEGSADIDQVDNLQEGPSKPVHSSTNYDDAMQFLKKKRYLQAASNN-SREYALNVGTIASQPSVTQAAVASVIDESTTASIL-DSQALNVEIKSNHDKNVIPDEVLQTLLDHYSHKPNGQHEISFSVADTEVTSSISINSSDVPEVTQSENVGSSSQASSSDKANMLQEYSKFLQQALDRTSQNDAYLNSPSLNFVTDNQTLPNPPAFSSIDKQVYAAMPINSFRSGMNSPLRTTPDKSHFGLIVGDSQHPFPFSGDETNHASATSTADFLDQVTSQKKAEAQPVHQAYQMSSFEQPFRAPYHGSRAGIATQFSTANGQVNLRGPGTSAEFSEFPLVNVNDNRAGMTSSPDATTGQTFG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UQR1-1", "uniprot_id": "ZN148_HUMAN", "id": "Q9UQR1-1", "name": "Zinc finger protein 148", "aln": "MNIDDKLEGLFLKCGGIDEMQSSRTMVVMGGVSGQSTVSGELQDSVLQDRSMPHQEILAADEVLQESE-----------MRQQDMISHDELMVHEETVKND-EEQMETHERLPQGLQYALNVPISVKQEITFTDVSEQLMRDKKQIREPVDLQKKKKRKQRSPAKILTINEDGSLGLKTPKSHVCEHCNAAFRTNYHLQRHVFIHTGEKPFQCSQCDMRFIQKYLLQRHEKIHTGEKPFRCDECGMRFIQKYHMERHKRTHSGEKPYQCEYCLQYFSRTDRVLKHKRMCHENHDKKLNRCAIKGGLLTSEEDSGFSTSPKDNSLPKKKRQKTEKKS------SGMDKESALDKSDLKKD---KNDYLPLYSSSTKVKDEYMVAEYAVEMPHSSVGGSHLEDASG---EIHPPKLVLKKINSKRSLKQP-LEQNQTISPLSTYEESKVSKYAFELVDKQALLDSEGNADIDQVDNLQEGPSKPVHSSTNYDDAMQFLKKKRYLQAASNN-SREYALNVGTIASQPSVTQAAVASVIDESTTASIL-ESQALNVEIKSNHDKNVIPDEVLQTLLDHYSHKANGQHEISFSVADTEVTSSISINSSEVPEVTPSENVGSSSQASSSDKANMLQEYSKFLQQALDRTSQNDAYLNSPSLNFVTDNQTLPNQPAFSSIDKQVYATMPINSFRSGMNSPLRTTPDKSHFGLIVGDSQHSFPFSGDETNHASATSTQDFLDQVTSQKKAEAQPVHQAYQMSSFEQPFRAPYHGSRAGIATQFSTANGQVNLRGPGTSAEFSEFPLVNVNDNRAGMTSSPDATTGQTFG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0MS83-1", "uniprot_id": "ZN148_DANRE", "id": "A0MS83-1", "name": "Zinc finger protein 148", "aln": "MNIDDKLEGMLLKYSPVGLQHPSRGLGPSR-VDGRGRRG--SLDMTLGERSLANHPLLAEDDDDEDEEEDDDDDLAGEGLTSHDLISQDDLMVHEETVKNDGQDEAAFSHRISNKLHYTLSMPVNIKQEMKVPDSLILNKKEKKPGRDPSDCHKKKKRKQRSPAKILTINEDGSLGHQNPKSHICEHCNAAFRTNYHLQRHVFIHTGEKPFQCNQCDMRFIQKYLLQRHEKIHTGEKPFRCDECGMKFIQKYHMERHKRTHSGEKPYQCDYCHQFFSRTDRVLKHRRMCHENKDRKVQKTAVKDSPLRTPENLGFSFPAKDCTLPKKKRQKTSDKSRASITNPAVDKVVEADMDEKTEDRLAKSECLPLYAVATKVKDEYVVTDYSVELPDSPPGSRHLAGEESNDEIISPPKLVLKKIASRRGFKQQALEQSQSLSPLSSFEESKVTRYTFEIVDNKGLLDVETNPDMESVEALQVGQAKPTGSSTNYDDAMQFVKKRRYLQAATANTSRDYALNVSSIVSQSSVTQASVATVIDETVPATILSETQTLNVEIKSSNEKNVLPDEVLQTLLDHYSNKANGQAEISFSVADTEVTSSISINSSD--ESSPAEALVTSSQAPPTEKASLLQEYSKFLQQALERTSQNDTYLNNQSLTFVNDSASLAGQPLFS--TEKQFTSPPR--FRPTMNSPLRSTLEKPNFNLLV-DTQHSFSFSGDETNPSSVSPTEDFLDQVTSPKKTDPQSISQTFQITTFDQNFRSQFPSSRSGISPQFSIASGQVTLRGHG-GADFPEFSLVN--ETRTQLTSSPDATSSQTFG", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*********::** . :. :.** : *.*:. . : .* :**:.:: :** *: ::.* : .:*:**:*:*********** ::: .*:.: *:*:*.:*:.:***:...* ::** *:* * :*********************** :.****:*****************************.********************************:**********************:** *:**********:******:*:*::: *:*.. * : *: *** ..** :********...** ..:** * .: .:* :.: ****: :*******:*::*:**:*.*. *. ** . .. * ********* *:*.:** ***.*::****::*:***::*:**:**::.*** * ..*::.*: ** * :**. ***********:**:******: * **:*****.:*.**.*****:**:****...*:** ::*:*******.::***:*************:*.*** ********************: * : :* : :****..::**.:************:******:***. **.**.*. :*.. * ** :: ::: * **. ******:* :*.:*.*:* *:**.*.******* :*.:.* ******** **::.*.: *::*:::*:* **: : .**:**:.*** *.***.*** * .*:*.**.*** :.*: :*******:.****", "identical_positions": 475, "similar_positions": 214, "identity": "57.86%" }, { "cls_id": "homologset.agr.MGI:1332235", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q90X44-2", "uniprot_id": "NRF1_DANRE", "id": "Q90X44-2", "name": "Nuclear respiratory factor 1", "aln": "----------------------------------------------------------MEDHTVHQTEHMTTIEAHAVSQQVGQVHVATYTEHGMLSADEDSPSSPDDDAYDDSDILNSTGTDEVTAHLAAAGPVGMAAAAAVATGKKRKRPHIFESNPSIRKRQQTRLLRKLRATLDEYTTRVGQQAIVLCISPSKPNPVFRVFGAAPLENVVRKYKSMILEDLENALAEHAPPGGGELS--SELPPLTIDGIPVSVDKMTQAQLRAFIPEMLKYSTGRGKPGWGKESCKPIWWPEDIPWANVRSDVRTEEQKQRVSWTQALRTIVKNCYKQHGREDLLYAFEDQVTTQVATTATHS------------IAHLVPSQTVVQTISNPDGTVSLIQVGTGATVATLADASELPGTVTVAQVN--------YSTVTDGEVEQNWATLQ-----------------------GGEMTIQTTQAS-EATQAVASLAEAAVAASQEMQTGATVTMALNRYSLEGALKFGEAAAHAVATLAEATLQGGGQIVLAGETAAAVGALTGVPDG---------------------------------------------------------------------SGLVQIPVSMYQTVVT--SLAQGNRPVQVAMAPVTTRIDN-TMTLDG-----------------QAVEVVTLEQ--------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q62792-1", "uniprot_id": "NRF1_RAT", "id": "Q62792-1", "name": "Nuclear respiratory factor 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VEQNWATLQ-----------------------GGEMTIQTTQAS-EATQAVASLAEAAVAASQEMQQGATVTMALN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q16656-1", "uniprot_id": "NRF1_HUMAN", "id": "Q16656-1", "name": "Nuclear respiratory factor 1", "aln": "----------------------------------------------------------MEEHGVTQTEHMATIEAHAVAQQVQQVHVATYTEHSMLSADEDSPSSPEDTSYDDSDILNSTAADEVTAHLAAAGPVGMAAAAAVATGKKRKRPHVFESNPSIRKRQQTRLLRKLRATLDEYTTRVGQQAIVLCISPSKPNPVFKVFGAAPLENVVRKYKSMILEDLESALAEHAP-APQEVN--SELPPLTIDGIPVSVDKMTQAQLRAFIPEMLKYSTGRGKPGWGKESCKPIWWPEDIPWANVRSDVRTEEQKQRVSWTQALRTIVKNCYKQHGREDLLYAFEDQQ-TQTQATATHS------------IAHLVPSQTVVQTFSNPDGTVSLIQVGTGATVATLADASELPTTVTVAQVN--------YSAVADGEVEQNWATLQ-----------------------GGEMTIQTTQAS-EATQAVASLAEAAVAASQEMQQGATVTMALN----------SEAAAHAVATLAEATLQGGGQIVLSGETAAAVGALTGVQDA---------------------------------------------------------------------NGLVQIPVSMYQTVVT--SLAQGNGPVQVAMAPVTTRISDSAVTMDG-----------------QAVEVVTLEQ--------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9WU00-1", "uniprot_id": "NRF1_MOUSE", "id": "Q9WU00-1", "name": "Nuclear respiratory factor 1", "aln": "----------------------------------------------------------MEEHGVTQTEHMATIEAHAVAQQVQQVHVATYTEHSMLSADEDSPSSPEDTSYDDSDILNSTAADEVTAHLAAAGPVGMAAAAAVATGKKRKRPHVFESNPSIRKRQQTRLLRKLRATLDEYTTRVGQQAIVLCISPSKPNPVFKVFGAAPLENVVRKYKSMILEDLESALAEHAP-APQEVN--SELPPLTIDGIPVSVDKMTQAQLRAFIPEMLKYSTGRGKPGWGKESCKPIWWPEDIPWANVRSDVRTEEQKQRVSWTQALRTIVKNCYKQHGREDLLYAFEDQQ-TQTQATTTHS------------IAHLVPSQTVVQTFSNPDGTVSLIQVGTGATVATLADASELPTTVTVAQVN--------YSAVADGEVEQNWATLQ-----------------------GGEMTIQTTQAS-EATQAVASLAEAAVAASQEMQQGATVTMALN----------SEAAAHAVATLAEATLQGGGQIVLSGETAAAVGALTGVQDA---------------------------------------------------------------------NGLVQIPVSMYQTVVT--SLAQGNGPVQVAMAPVTTRISDSAVTMDG-----------------QAVEVVTLEQ--------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q24312-1", "uniprot_id": "EWG_DROME", "id": "Q24312-1", "name": "DNA-binding protein Ewg", "aln": "MATTSYRLVVAPAGSQRSSTGNVVVTTTSSGSHSSNGANGGTGGTSAGSSTLGSGLNVTTITATSGGQLQSAGNTSQSNGTTYKIEMLEEDIQSLGSDDDDEDLISSDGSLYEGDLGSMPVNDDVAHQLAAAGPVGVAAAAAIASSKKRKRPHCFETNPSVRKRQQNRLLRKLRAIIYEFTGRVGKQAVVLVATPGKPNTSYKVFGAKPLEDVLRNLKNIVMDELDNALAQQAPPPPQDDPSLFELPGLVIDGIPTPVEKMTQAQLRAFIPLMLKYSTGRGKPGWGRESTRPPWWPKELPWANVRMDARSEDDKQKISWTHALRKIVINCYKYHGREDLLPTFADDEDKVNALISQSGDEDEDMELSNPPTIHTVTTMTPPTGNSNQPQQVNVVKINSAGTVITTHTAQSNTPAPTIIQSTNNQHVTTTATLPASTKIEICQAPAQNQQHHQHHQTHLPNAVHIQPVAGGQPQTIQLTTASGTATATAVQTTAAAVSAAQAHAHSQSQAHSQSSANQTVTAQQIANAQVCIEPITLSDVDYTTQTVLSQNADGTVSLIQVDPNNPIITLPDGTTAQVQGVATLHQGEGGATIQTVQSLTDVNGHENMTVDLTETQDGQIYITTEDGQGYPVSVSNVISVPVSMYQSVMANVQQIQTNSDGTVCLAPMQVENGDQLETITMSPGMHQMMIQGGPGQEPQLVQVVSLKDATLLSKAMEAINSGNVKSEDTIIMEQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* *. * * *** * ** ** :... : ***:*:* . : : : . ", "identical_positions": 17, "similar_positions": 14, "identity": "2.32%" }, { "cls_id": "homologset.agr.MGI:1332236", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99L43-1", "uniprot_id": "CDS2_MOUSE", "id": "Q99L43-1", "name": "Phosphatidate cytidylyltransferase 2", "aln": "MTELRQRVVRED-APPED-KESESEAKLDGETASDS----ESRAETAP-----------LPTSVDDTPEVLNRALSNLSSRWKNWWVRGILTLAMIAFFFIIIYLGPMVLMMIVMCVQIKCFHEIITIGYNVYHSYDLPWFRTLSWYFLLCVNYFFYGETVTDYFFTLVQREEPLRILSKYHRFISFALYLTGFCMFVLSLVKKHYRLQFYMFGWTHVTLLIVVTQSHLVIHNLFEGMIWFIVPISCVICNDIMAYMFGFFFGRTPLIKLSPKKTWEGFIGGFFATVVFGLLLSYVMSGYRCFVCPVEYNNDTNSFTVDCEPSDLFRLQEYNIPGVIQSAIGWKTVRMYPFQIHSIALSTFASLIGPFGGFFASGFKRAFKIKDFANTIPGHGGIMDRFDCQYLMATFVNVYIASFIRGP---NPSKLIQQFLTLRPDQQLHIFNTLKSHLTDKGILTSALEDE----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q91XU8-1", "uniprot_id": "CDS2_RAT", "id": "Q91XU8-1", "name": "Phosphatidate cytidylyltransferase 2", "aln": "MTELRQRAVRED-APPED-KESESEAKLDGETASDS----ESRAETAP-----------PPTSIDDTPEVLNRALSNLSSRWKNWWVRGILTMAMIAFFFIIIYLGPMVLMMIVMCVQIKCFHEIITIGYNVYHSYDLPWFRTLSWYFLLCVNYFFYGETVTDYFFTLVQREEPLRILSKYHRFISFTLYLTGFCMFVLSLVKKHYRLQFYMFGWTHVTLLIVVTQSHLVIHNLFEGMIWFIVPISCVICNDIMAYMFGFFFGRTPLIKLSPKKTWEGFIGGFFATVVFGLLLSYVMSGYRCFVCPVEYNNDTNSFTVDCEPSDLFRLQEYNIPGVIQSLVGWKTMRMYPFQIHS-ALSTFASLIGPFGGFFASGFKRAFKIKDFANTIPGHGGIMDRFDCQYLMATFVNVYIASFIRGP---NPSKLIQQFLTLRPDQQLHIFNTLKSHLTDKGILMSALEEE----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O95674-1", "uniprot_id": "CDS2_HUMAN", "id": "O95674-1", "name": "Phosphatidate cytidylyltransferase 2", "aln": "MTELRQRVAHEPVAPPED-KESESEAKVDGETASDS----ESRAESAP-----------LPVSADDTPEVLNRALSNLSSRWKNWWVRGILTLAMIAFFFIIIYLGPMVLMIIVMCVQIKCFHEIITIGYNVYHSYDLPWFRTLSWYFLLCVNYFFYGETVTDYFFTLVQREEPLRILSKYHRFISFTLYLIGFCMFVLSLVKKHYRLQFYMFGWTHVTLLIVVTQSHLVIHNLFEGMIWFIVPISCVICNDIMAYMFGFFFGRTPLIKLSPKKTWEGFIGGFFATVVFGLLLSYVMSGYRCFVCPVEYNNDTNSFTVDCEPSDLFRLQEYNIPGVIQSVIGWKTVRMYPFQIHSIALSTFASLIGPFGGFFASGFKRAFKIKDFANTIPGHGGIMDRFDCQYLMATFVNVYIASFIRGP---NPSKLIQQFLTLRPDQQLHIFNTLRSHLIDKGMLTSTTEDE----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P56079-1", "uniprot_id": "CDS_DROME", "id": "P56079-1", "name": "Phosphatidate cytidylyltransferase, photoreceptor-specific", "aln": "MAEVRRRKGEDE--PLEDTAISGSDAANKRNSAADSSDHVDSEEEKIPEEKFVDELAKNLPQGTDKTPEILDSALKDLPDRWKNWVIRGIFTWIMICGFALIIYGGPLALMITTLLVQVKCFQEIISIGYQVYRIHGLPWFRSLSWYFLLTSNYFFYGENLVDYFGVVINRVEYLKFLVTYHRFLSFALYIIGFVWFVLSLVKKYYIKQFSLFAWTHVSLLIVVTQSYLIIQNIFEGLIWFIVPVSMIVCNDVMAYVFGFFFGRTPLIKLSPKKTWEGFIGGGFATVLFGILFSYVLCNYQYFICPIQYSEEQGRMTMSCVPSYLFTPQEYSLK---LFGIG-KTLNLYPFIWHSISLSLFSSIIGPFGGFFASGFKRAFKIKDFGDMIPGHGGIMDRFDCQFLMATFVNVYISSFIRTP---SPAKLLTQIYNLKPDQQYQIYQSLKDNLGD--MLT----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38221-1", "uniprot_id": "CDS1_YEAST", "id": "P38221-1", "name": "Phosphatidate cytidylyltransferase", "aln": "MSDNPEMKPHGT---SKEIVESVTDATSKAIDKLQEELHKDASESVTP--------------------VTKESTAATKESRKYNFFIRTVWTFVMISGFFITLASGHAWCIVLILGCQIATFKECIAVTSASGREKNLPLTKTLNWYLLFTTIYYLDGKSLFKFFQATFYEYPVLNFIVTNHKFICYCLYLMGFVLFVCSLRKGFLKFQFGSLCVTHMVLLLVVFQAHLIIKNVLNGLFWFLLPCGLVIVNDIFAYLCGITFGKTKLIEISPKKTLEGFLGAWFFTALASIILTRILSPYTYLTCPVEDLHTNFFSNLTCELNPVFLPQVYRLPPIFFDKVQINSITVKPIYFHALNLATFASLFAPFGGFFASGLKRTFKVKDFGHSIPGHGGITDRVDCQFIMGSFANLYYETFISEHRITVDTVLSTILMNLNDKQIIELIDILIRFLSKKGIISAKNFEKLADIFNVTKKSLTNHS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:: . . :: * ::* . :. :: . * : : .* *: :* : * **. * : : * :: : *: *:* *:: : .** ::*.**:*: *:: *:.: .:* . . . *.:: . *:*:.: **: ** ** ** * . ** : **: **:** *::*:*:*:::*::**::* . :: **::**: *: **:* **::***** ***:*. * *.: .:::: ::. * : **:: . .: * . :* * * : : ::: : *: *: *: *:*::.*********:**:**:***.. ******* **.***::*.:*.*:* :** : * : .*. .* .: : * * . :: ", "identical_positions": 125, "similar_positions": 138, "identity": "26.04%" }, { "cls_id": "homologset.agr.MGI:1332237", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O08664-1", "uniprot_id": "BCL7C_MOUSE", "id": "O08664-1", "name": "B-cell CLL/lymphoma 7 protein family member C", "aln": "MAGRTVRAETRSRAKDDIKKVMATIEKVRRWEKRWVTVGDTSLRIFKWVPVVDPQEEERRRAGGGAERSRGRERRGRGTSPRGGGPLILLDLN-DENSNQSFHSEGSLQKGAEPSPGGTPQPSRPGSPTGPPEVITEDTQPPQLGQERDPGGTPAGGTDEPPKLTKEEPVPELLEAEAPEAYPVFEPVPSVPEAAQGDTEDSEGAPPLKRICPNAPDP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZUL4-1", "uniprot_id": "D3ZUL4_RAT", "id": "D3ZUL4-1", "name": "", "aln": "MAGRTVRAETRSRAKDDIKKVMATIEKVRRWEKRWVTVGDTSLRIFKWVPVVDPQEEERRRAGGGAERSRGRERRGRGTSPRGGGPLILLDLNADENSNQSFHSEGSLQKGTEPSPGGTPQPSRPGSPTGPPEVITEDTQPPQLGQERDPGGTPAGGTDEPPKLTKEEPVPELLEAEAPEAYPVFEPVPPVPEAAQGDTEDSEGAPPLKRICPNAPDP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8WUZ0-1", "uniprot_id": "BCL7C_HUMAN", "id": "Q8WUZ0-1", "name": "B-cell CLL/lymphoma 7 protein family member C", "aln": "MAGRTVRAETRSRAKDDIKKVMATIEKVRRWEKRWVTVGDTSLRIFKWVPVVDPQEEERRRAGGGAERSRGRERRGRGASPRGGGPLILLDLN-DENSNQSFHSEGSLQKGTEPSPGGTPQPSRPVSPAGPPEGVPEEAQPPRLGQERDPGGITAGSTDEPPMLTKEEPVPELLEAEAPEAYPVFEPVPPVPEAAQGDTEDSEGAPPLKRICPNAPDP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O76857-1", "uniprot_id": "O76857_DROME", "id": "O76857-1", "name": "", "aln": "-MSRSVRAETRSRAKDDIKRVMQAVDKVRHWEKKWVTISDTTMKIYKWVPIASASEKKAKLESSPGSAAVRRPPPGSGVTPVGGS-----------------------KSDKENSQKGTPTPP---QITPSYQGLTAEDSNTCFSVVSDSQGA--------------------------------DFVSSMPFSEDSNSQGSDG--PVKRLKTSD---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .*:**************:** :::***:***:***:.**:::*:****:....*:: : .. .. : * * *.:* **. :.. * * *** *. . : . : :. : . . :. *. * : *..:* : :.:::.*:* *:**: .. ", "identical_positions": 55, "similar_positions": 62, "identity": "25.23%" }, { "cls_id": "homologset.agr.MGI:1332238", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B1H245-1", "uniprot_id": "B1H245_RAT", "id": "B1H245-1", "name": "", "aln": "MSGRSVRAETRSRAKDDIKKVMAAIEKVRKWEKKWVTVGDTSLRIFKWVPVTDSKEKEKSKSNNTAAREPNGFPSDASAN--SSLLLEFQDENSNQSSVSDVYQ--LKVDSSTNSSPSPQQSESLSPA-HTSDFRTDDSQPPT--LGQEILE---EPSLPASEVADEPPTLTKEEPVPIETQTTEEEEDSGAPPLKRFCVDQPVVPQTTSES", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q921K9-1", "uniprot_id": "BCL7B_MOUSE", "id": "Q921K9-1", "name": "B-cell CLL/lymphoma 7 protein family member B", "aln": "MSGRSVRAETRSRAKDDIKKVMAAIEKVRKWEKKWVTVGDTSLRIFKWVPVTDSKEKEKSKSNNTAAREPNGFPSDASAN--SSLLLEFQDENSNQSSVSDVYQ--LKVDSSTNSSPSPQQSESLSPA-HTSDFRTDDSQPPT--LGQEILE---EPSLPASEVADEPPTLTKEEPVPVETQTTEEEEDSGAPPLKRFCVDQPVVPQTTSES", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BQE9-1", "uniprot_id": "BCL7B_HUMAN", "id": "Q9BQE9-1", "name": "B-cell CLL/lymphoma 7 protein family member B", "aln": "MSGRSVRAETRSRAKDDIKKVMAAIEKVRKWEKKWVTVGDTSLRIFKWVPVTDSKEKEKSKSNSSAAREPNGFPSDASAN--SSLLLEFQDENSNQSSVSDVYQ--LKVDSSTNSSPSPQQSESLSPA-HTSDFRTDDSQPPT--LGQEILE---EPSLPSSEVADEPPTLTKEEPVPLETQVVEEEEDSGAPPLKRFCVDQPTVPQTASES", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2BIL8-1", "uniprot_id": "BC7BB_DANRE", "id": "A2BIL8-1", "name": "B-cell CLL/lymphoma 7 protein family member B-B", "aln": "MSGRSVRAETRSRAKDDIKKVMAAIERVRRWEKKWVTVGDTSLRIFKWVPVTETKQIYKPKGAGPAVRELKGFPTDVVLENARSVLLDFQDDNSNQSFLSDAYQSNTKVDSSSNSSPQ-HVSEAVSPS-HPPYYRTEDSQPPT--LGQESMEAEREASTTSSEVTDEPPTLIKEDVLSLSTQ--EEEEAIGAPPLKRVCTEH---NSTVS--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6NWJ0-1", "uniprot_id": "BC7BA_DANRE", "id": "Q6NWJ0-1", "name": "B-cell CLL/lymphoma 7 protein family member B-A", "aln": "MSGRSVRAETRSRAKDDIKKVMAAIERVRRWEKKWVTVGDTSLRIFKWVPVVDTKEKEKSKVSVGGEMQRKNFPSEESSDNACSVLLDFQDENSNQSSLSDSYQHKAAADSSNNSSPP--ASEPVSPAPQSLDYRTDDPQPPT--LGQEIME---EPLLQSSEIADEPPTLIKEDLLPLTAQ--EDEDSCGAPPLKRICTEQVSVIQMVPLS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O76857-1", "uniprot_id": "O76857_DROME", "id": "O76857-1", "name": "", "aln": "-MSRSVRAETRSRAKDDIKRVMQAVDKVRHWEKKWVTISDTTMKIYKWVPIASASEKKAKLESSPGSAAVRRPPPG--------------------SGVTPVGGSKSDKENSQKGTPT---PPQITPS-----YQGLTAEDSNTCFSVVS----------DSQGADFVSSMPFSE---------DSNSQGSDGPVKRLKTSD----------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .****************:** *:::**:*******:.**:::*:****:..:.: . . *. * :: :.* :.:* . ::*: :: .: .. :. *: :* .:: .: :.:. . *:**. ... ", "identical_positions": 45, "similar_positions": 57, "identity": "21.23%" }, { "cls_id": "homologset.agr.MGI:1332240", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q920H8-1", "uniprot_id": "HEPH_RAT", "id": "Q920H8-1", "name": "Hephaestin", "aln": "MKAGHLLWALLLMHSLCSLPTDGAIRNYYLGIQDIQWNYAPKGRNVITNQTLNNDTVASSFLKSGKNRIGGTYKKTVYKEYSDGTYTNEIAKPAWLGFLGPLLKAEMGDVILIHLKNFASRPYTIHPHGVFYEKDSEGSLYPDGSSGYLKADDSVPPGGSHVYNWSIPEGHAPTEADPACLTWIYHSHVDAPRDIATGLIGPLITCKRGTLDGNSPPQRKDVDHNFFLLFSVIDENLSWHLDDNIATYCSDPASVDKEDGPFQDSNRMHAINGFVFGNLPELSMCAQKHVAWHLFGMGNEIDVHTAFFHGQTLSIRGHRTDVAHIFPATFVTAEMVPQKSGTWLISCVVNSHLKSGMQAFYKVDSCSMDPPVEQLTGKVRQYFIQAHEIQWDYGPIGHDGRTGKSLREPGSGPDKYFQKSSSRIGGTYWKVRYEAFQDETFQERLHQEEETHLGILGPVIRAEVGDTIQVVFYNRASQPFSIQPHGVFYEKSSEGTVYNDGTSYP-KVAKSFEKVTYYWTVPPHAGPTAEDPACLTWMYFSAADPTRDTNSGLVGPLLVCKAGALGEDGKQKGVDKEFFLLFTIFDENESWYNNANQAAGMLDSRLLSEDVEGFEDSNRMHAINGFLFSNLPRLDICKGDTVAWHLLGLGTENDVHGVMFEGNTLQLQGMRKSAAMLFPHTFVTAIMQPDNPGIFEIYCQAGSHREAGMQAIYNVSQCSSHQDSPRQHYQASRVYYIMAEEIEWDYCPDRSWELEWYNTSEKDSYGHVFLSNKDGLLGSKYKKAVFREYTDGTFRIPQPRSGPEEHLGILGPLIRGEVGDILTVVFKNKASRPYSIHAHGVLESSTGWPQAAEPGEVLTYQWNIPERSGPGPSDSACVSWIYYSAVDPIKDMYSGLVGPLVICRNGILEPNGGRNDMDREFALLFLIFDENQSWYLKENIATYGPQETSHVNLQDATFLESNKMHAINGKLYANLRGLTVYQGERVAWYMLAMGQDTDIHTVHFHAESFLYQNGHSYRADVVDLFPGTFEVVEMVASNPGAWLMHCHVTDHVHAGMETIFTVLSHEEHFSTMTTITKEIGKAVILQNIGEGNVKMLGMNIPVKNVEILSSALIAICVVLLLIALALGGVVWYQHRQRKLRRNRRSILDDSFKLLSLKQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z0Z4-1", "uniprot_id": "HEPH_MOUSE", "id": "Q9Z0Z4-1", "name": "Hephaestin", "aln": "MKAGHLLWALLLMHSLWSIPTDGAIRNYYLGIQDMQWNYAPKGRNVITNQTLNNDTVASSFLKSGKNRIGSSYKKTVYKEYSDGTYTEEIAKPAWLGFLGPLLQAEVGDVILIHLKNFASRPYTIHPHGVFYEKDSEGSLYPDGSSGYLKADDSVPPGGSHVYNWSIPESHAPTEADPACLTWIYHSHVDAPRDIATGLIGPLITCKRGTLDGNSPPQRKDVDHNFFLLFSVIDENLSWHLDDNIATYCSDPASVDKEDGAFQDSNRMHAINGFVFGNLPELSMCAQKHVAWHLFGMGNEIDVHTAFFHGQMLSIRGHHTDVANIFPATFVTAEMVPQKSGTWLISCEVNSHLRSGMQAFYKVDSCSMDPPVDQLTGKVRQYFIQAHEIQWDYGPIGYDGRTGKSLREPGSGPDKYFQKSSSRIGGTYWKVRYEAFQDETFQERVHQEEETHLGILGPVIRAEVGDTIQVVFYNRASQPFSIQPHGVFYEKNSEGTVYNDGTSHP-KVAKSFEKVTYYWTVPPHAGPTAQDPACLTWMYFSAADPTRDTNSGLVGPLLVCKAGALGADGKQKGVDKEFFLLFTVFDENESWYNNANQAAGMLDSRLLSEDVEGFQDSNRMHAINGFLFSNLPRLDMCKGDTVAWHLLGLGTETDVHGVMFEGNTVQLQGMRKGAVMLFPHTFVTAIMQPDNPGIFEIYCQAGSHREEGMQAIYNVSQCSSHQDSPRQHYQASRVYYIMAEEIEWDYCPDRSWELEWHNTSEKDSYGHVFLSNKDGLLGSKYKKAVFREYTDGTFRIPRPRSGPEEHLGILGPLIRGEVGDILTVVFKNKASRPYSIHAHGVLESNTGGPQAAEPGEVLTYQWNIPERSGPGPSDSACVSWIYYSAVDPIKDMYSGLVGPLVICRNGILEPNGGRNDMDREFALLFLIFDENQSWYLKENIATYGPQESSHVNLKDATFLESNKMHAINGKLYANLRGLTVYQGERVAWYMLAMGQDTDIHTVHFHAESFLYQNGQSYRADVVDLFPGTFEVVEMVASNPGTWLMHCHVTDHVHAGMETIFTVLSHEEHFSTMTTITKEIGKAVILRDIGGDNVKMLGMNIPIKDVEILSSALIAICVLLLLIALALGGVVWYQHRQRKLRRNRRSILDDSFKLLSLKQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BQS7-1", "uniprot_id": "HEPH_HUMAN", "id": "Q9BQS7-1", "name": "Hephaestin", "aln": "MESGHLLWALLFMQSLWPQLTDGATRVYYLGIRDVQWNYAPKGRNVITNQPLDSDIVASSFLKSDKNRIGGTYKKTIYKEYKDDSYTDEVAQPAWLGFLGPVLQAEVGDVILIHLKNFATRPYTIHPHGVFYEKDSEGSLYPDGSSGPLKADDSVPPGGSHIYNWTIPEGHAPTDADPACLTWIYHSHVDAPRDIATGLIGPLITCKRGALDGNSPPQRQDVDHDFFLLFSVVDENLSWHLNENIATYCSDPASVDKEDETFQESNRMHAINGFVFGNLPELNMCAQKRVAWHLFGMGNEIDVHTAFFHGQMLTTRGHHTDVANIFPATFVTAEMVPWEPGTWLISCQVNSHFRDGMQALYKVKSCSMAPPVDLLTGKVRQYFIEAHEIQWDYGPMGHDGSTGKNLREPGSISDKFFQKSSSRIGGTYWKVRYEAFQDETFQEKMHLEEDRHLGILGPVIRAEVGDTIQVVFYNRASQPFSMQPHGVFYEKDYEGTVYNDGSSYPGLVAKPFEKVTYRWTVPPHAGPTAQDPACLTWMYFSAADPIRDTNSGLVGPLLVCRAGALGADGKQKGVDKEFFLLFTVLDENKSWYSNANQAAAMLDFRLLSEDIEGFQDSNRMHAINGFLFSNLPRLDMCKGDTVAWHLLGLGTETDVHGVMFQGNTVQLQGMRKGAAMLFPHTFVMAIMQPDNLGTFEIYCQAGSHREAGMRAIYNVSQCPGHQATPRQRYQAARIYYIMAEEVEWDYCPDRSWEREWHNQSEKDSYGYIFLSNKDGLLGSRYKKAVFREYTDGTFRIPRPRTGPEEHLGILGPLIKGEVGDILTVVFKNNASRPYSVHAHGVLESTTVWPLAAEPGEVVTYQWNIPERSGPGPNDSACVSWIYYSAVDPIKDMYSGLVGPLAICQKGILEPHGGRSDMDREFALLFLIFDENKSWYLEENVATHGSQDPGSINLQDETFLESNKMHAINGKLYANLRGLTMYQGERVAWYMLAMGQDVDLHTIHFHAESFLYRNGENYRADVVDLFPGTFEVVEMVASNPGTWLMHCHVTDHVHAGMETLFTVFSRTEHLSPLTVITKETEKAVPPRDIEEGNVKMLGMQIPIKNVEMLASVLVAISVTLLLVVLALGGVVWYQHRQRKLRRNRRSILDDSFKLLSFKQ", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*::********:*:** . **** * *****:*:***************.*:.* ********.*****.:****:****.*.:**:*:*:*********:*:**:************:*************************** *************:***:***.****:**********************************:*********:****:*******:********::**************** .**:******************.*****:********************** *: ***:****:************* :.******* ****::.****:***.**** ***: **********:**********:*:** ***.****** .**:***************************::* **: ******************************:*********. ********:*:* ***.****** ***********:*************** **************:***** ****************::***:***.******.*** ******:***:********************:****************.*******:***:*******.*.******** ******* * ************ **:********..** :***:***:*:*******:*********** **:* *******::***********:*****************:**:*************:*************:******:********.* * *******:**************.***************************.**::*****:***.****************:****:**:**:*.*:.. :**:* ***********************:****************.*:**:*********:**..************************:*****************:***:*: **:*.:*.**** *** ::* .*******:**:*:**:*:*.*:**.* ***:.********************************:**", "identical_positions": 971, "similar_positions": 142, "identity": "83.85%" }, { "cls_id": "homologset.agr.MGI:1332242", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z304-1", "uniprot_id": "MYCS_MOUSE", "id": "Q9Z304-1", "name": "Protein S-Myc", "aln": "-----------------------------------------------------------------------------MLSCTTS-----TMPGMICKNSDLEFDLLKPCFYPEEDDIYFGGHNSTPPGEDIWKKFELLPTPRLSPDSALAEHS-LEPVNWATEMLLPEADLWSNPGEEE-VFGQGG--LRGCTSNPIILQDCMWSG-----FSNPGKPESVVSEKLPGGYRS-------LAVGAGTLAPGAAAAASSAGHERSGTAGVGR----------------------GKAAWLTELSHLDLECVDPAVVF-FPANKREPMPVPTIPTSTGSA----------------------------ISLGDHQGLSSSLE----------------DFLSNSGS----VEEGGEEIYVVMLEETQFS-------------KTVSRLPTAAHQEN------------AALSPGCAQSSELILKRYDLIQEQHNYAAPPLPYVDREDARPQKKPRSHTSL-ALKCVFRPKAPR--------------------------------------------------LGSRNNSDWEN----------------------------------IERRRNHNRMERQRRDIMRSSFLNLRDLVPELVHNEKAAKVVILKKATEYIHTLQADESKLLVERKKLYERQQQLLQKIKQYALC---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P23999-1", "uniprot_id": "MYCS_RAT", "id": "P23999-1", "name": "Protein S-Myc", "aln": "-----------------------------------------------------------------------------MLSCTTS-----TMPGMICKNSDLEFDSLKPCFYPEDDDIYFGGRNSTPPGEDIWKKFELLPTPRLSPGRALAEDS-LEPANWATEMLLPEADLWSNPAEEEDIFGLKG--LSGSSSNPVVLQDCMWSG-----FSSREKPETVVSEKLPGGCGS-------LAVGAGTLVPGAAAATS-AGHARSGTAGVGR----------------------RKAAWLTELSHLDSECVD-SAVI-FPANKRESMPVATIPASAGAA----------------------------ISLGDHQGLSSSLE----------------DFLSNSGY----VEEGGEEIYVVMLGETQFS-------------KTVTKLPTAAHSEN------------AALTPECAQSGELILKRSDLIQEQHNYAAPPLPYA--EDARPLKKPRSQDPLGPLKCVLRPKAPR--------------------------------------------------LRSRSNSDLED----------------------------------IERRRNHNRMERQRRDIMRSSFLNLRDLVPELVHNEKAAKVVILKKATEYIHTLQTDESKLLVEREKLYERKQQLLEKIKQSAVC---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P04198-1", "uniprot_id": "MYCN_HUMAN", "id": "P04198-1", "name": "N-myc proto-oncogene protein", "aln": "-----------------------------------------------------------------------------MPSCSTS-----TMPGMICKNPDLEFDSLQPCFYPDEDDFYFGGPDSTPPGEDIWKKFELLPTPPLSPSRGFAEHS-SEPPSWVTEMLL-ENELWGSPAEED-AFGLGG--LGGLTPNPVILQDCMWSG-----FSAREKLERAVSEKLQHGRGP-------PTAGSTAQSPGAGAASP-AGRGHGGAAGAGR----------------------AGAALPAELAHPAAECVDPAVVFPFPVNKREPAPVPAAPASAPAAGPAVASGAGIAAPAGAPGVAPPRPGGRQTSGGDHKALSTSGE----------------DTLSDSDDEDDEEEDEEEEIDVVTVEKRRSSS----------NTKAVTTFTITVRPKN------------AALGPGRAQSSELILKRCLPIHQQHNYAAP-SPYVESEDAPPQKKIKSEASPRPLKSVIPPKAKS--------------------------------------------------LSPR-NSDSED----------------------------------SERRRNHNILERQRRNDLRSSFLTLRDHVPELVKNEKAAKVVILKKATEYVHSLQAEEHQLLLEKEKLQARQQQLLKKIEHARTC---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W4S7-1", "uniprot_id": "MYC_DROME", "id": "Q9W4S7-1", "name": "Myc proto-oncogene protein", "aln": "MALYRSDPYSIMDDQLFSNISIFDMDNDLYDMDKLLSSSTIQSDLEKIEDMESVFQDYDLEEDMKPEIRNIDCMWPAMSSCLTSGNGNGIESGNSAASSYSETGAVSLAMVSGSTNLYSAYQRSQTTDNTQSNQQHVVNSAENMPVIIKKELADLDYTVCQKRLRLSGGDKKSQIQDEVHLIPPGGSLLRKRNNQDIIRKSGELSGSDSIKYQRPDTPHSLTDEVAASEFRHNVDLRACVMGSNNISLTGNDSDVNYIKQISRELQNTGKDPLPVRYIPPINDVLDVLNQHSNSTGGQQQLNQQQLDEQQQAIDIATGRNTVDSPPTTGSDSDSDDGEPLN--FDLRHHRTSKSGSNASITTNNNNSNNKNNKLKNNSNGMLHMMHITDHSYTRCNDMVDDGPNLETPSDSDEEIDVVSYTDKKLPTNPSCHLMGALQFQMAHKISIDHMKQKPRYNNFNLPYTPASSSPVKSVANSRYPSPSSTPYQNCSSASPSYSPLSVDSSNVSSSSSSSSSQSSFTTSSSNKGRKRSSLKDPGLLISSSSVYLPGVNNKVTHSSMMSKKSRGKKVVGTSSGNTSPISSGQDVDAMDRNWQRRSGGIATSTSSNSSVHRKDFVLGFDEADTIEKRNQHNDMERQRRIGLKNLFEALKKQIPTIRDKERAPKVNILREAAKLCIQLTQEEKELSMQRQLLSLQLKQRQDTLASYQMELNESRSVSG", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * ** ** .* . .. * . :. .: . . ::* . * ...: :: .:: :. * * : : ..: * : .. :* : * * . : :: :. ** :. . . ..* . .* : : ..*: :. :* : : : : : *. :. *.. :.: . * ..:: *... : : : :.. .: *** ** . : . : . :. :: *: * : :.. . :: . *:* . :.: .. * . .:. *. : . : * : *:*.:** :***** ::. * *:. :* : .:*:*.** **::*:: * :* :* :::: * : :* ..: ", "identical_positions": 61, "similar_positions": 150, "identity": "8.48%" }, { "cls_id": "homologset.agr.MGI:1332243", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9R0E0-1", "uniprot_id": "CEGT_RAT", "id": "Q9R0E0-1", "name": "Ceramide glucosyltransferase", "aln": "MALLDLAQEGMALFGFVLFVVLWLMHFMSIIYTRLHLNKKATDKQPYSK-LPGVSLLKPLKGVDPNLINNLETFFELDYPKYEVLLCVQDHDDPAIEVCKKLLGKYPNVDARLFIGGKKVGINPKINNLMPAYEVAKYDLIWICDSGIRVIPDTLTDMVNQMTERVGLVHGLPYVADRQGFAATLEQVYFGTSHPRSYISANVTGFKCVTGMSCLMRKDVLDQAGGLIAFAQYIAEDYFMAKAIADRGWKFSMSTQVAMQNSGSYSISQFQSRMIRWTKLRINMLPATIICEPISECFVASLIIGWAAHHVFRWDIMVFFMCHCLAWFIFDYIQLRGVQGGTLCFSKLDYAVAWFIRESMTIYIFLSALWDPTISWRAGRYRLRCGGTAEEILDV---------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88693-1", "uniprot_id": "CEGT_MOUSE", "id": "O88693-1", "name": "Ceramide glucosyltransferase", "aln": "MALLDLAQEGMALFGFVLFVVLWLMHFMSIIYTRLHLNKKATDKQPYSK-LPGVSLLKPLKGVDPNLINNLETFFELDYPKYEVLLCVQDHDDPAIDVCKKLLGKYPNVDARLFIGGKKVGINPKINNLMPAYEVAKYDLIWICDSGIRVIPDTLTDMVNQMTEKVGLVHGLPYVADRQGFAATLEQVYFGTSHPRSYISANVTGFKCVTGMSCLMRKDVLDQAGGLIAFAQYIAEDYFMAKAIADRGWRFSMSTQVAMQNSGSYSISQFQSRMIRWTKLRINMLPATIICEPISECFVASLIIGWAAHHVFRWDIMVFFMCHCLAWFIFDYIQLRGVQGGTLCFSKLDYAVAWFIRESMTIYIFLSALWDPTISWRTGRYRLRCGGTAEEILDV---------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q16739-1", "uniprot_id": "CEGT_HUMAN", "id": "Q16739-1", "name": "Ceramide glucosyltransferase", "aln": "MALLDLALEGMAVFGFVLFLVLWLMHFMAIIYTRLHLNKKATDKQPYSK-LPGVSLLKPLKGVDPNLINNLETFFELDYPKYEVLLCVQDHDDPAIDVCKKLLGKYPNVDARLFIGGKKVGINPKINNLMPGYEVAKYDLIWICDSGIRVIPDTLTDMVNQMTEKVGLVHGLPYVADRQGFAATLEQVYFGTSHPRYYISANVTGFKCVTGMSCLMRKDVLDQAGGLIAFAQYIAEDYFMAKAIADRGWRFAMSTQVAMQNSGSYSISQFQSRMIRWTKLRINMLPATIICEPISECFVASLIIGWAAHHVFRWDIMVFFMCHCLAWFIFDYIQLRGVQGGTLCFSKLDYAVAWFIRESMTIYIFLSALWDPTISWRTGRYRLRCGGTAEEILDV---------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W297-1", "uniprot_id": "Q9W297_DROME", "id": "Q9W297-1", "name": "ceramide glucosyltransferase", "aln": "MSHLPLPLYGFAAFFMVFWLGTWMVHVIAICYGRYKLHKKSCKLPTEAQPLPGVSILKPLMGVDPNLQHNLETFFTMDYPLYELLFCVEDKEDPAIQLVERLLAKYPLVDAALFVGGSDVGVNPKINNIHPGYMAAKYDFVMISDSGIKMKDDTLLDMVQNMSEKHALVHQMPFTCDRDGFAATFEKVFFGTVQSRIYLSADVLGINCHTGMSCLLRKAVIDQLGGLRAFGCYLAEDFFIARSVTRLGWKMRISNQPALQNSGLCDIGSFQARLIRWAKLRVAMVPTTILLEPLSECMILGAIAAWSASVLFSWDPLVFYLVHVLCWFLSDWLLLSIVQHGSMPFHKFEFVVGWLFRELTGPYLFLHALWNPAIRWRARTYKLHWGGVAYELNSLASDAANDPLAPQPQPAPTLEPAVVNAGTTGDTLICTGAKQRLLVS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: * *. *:* * :*::: *::*.::* * * :*:**: . . :: *****:**** ****** :****** :*** **:*:**:*::****:: ::**.*** *** **:**..**:******: *.* .****:: *.****:: *** ***::*:*: .*** :*:..**:*****:*:*:*** :.* *:**:* *::* ******:** *:** *** **. *:***:*:*:::: **:: :*.* *:**** .*..**:*:***:***: *:*:**: **:***:: . * .*:* :* ** :**:: * *.**: *:: * ** *:: * *:::.*.*::** *:** ***:*:* **: *:*: **.* *: .: ", "identical_positions": 200, "similar_positions": 121, "identity": "45.45%" }, { "cls_id": "homologset.agr.MGI:1332247", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99J27-1", "uniprot_id": "ACATN_MOUSE", "id": "Q99J27-1", "name": "Acetyl-coenzyme A transporter 1", "aln": "MSPTISHKDSSRQRRSGMFSHALDMKSGPLPPGGWDDSRRDSVGGEGDREVLLGDAGPGDLPKAPRS--YRSELSSILLLLFLYVLQGIPLGLAGSIPLILQS---KNVSYTDQAFFSFVFWPFSLKLLWAPLVDAVYFKNFGRRKSWLVPTQYTLGIFMIYLSTQVDR------------LLGNIDGRTPDVVALTVTFFLFEFLAATQDIAVDGWALTMLSRENVGYASTCNSVGQTAGYFLGNVLFLALESADFCNKYLRFQPQPRGIVTLSDFLFFWGTVFLITTTLVALLKKENR---------------------------EASIVKEETQGITDTYKLLFSIIKMPAVLAFCLLILTSKIGFSAADAVTGLKLVEEGVPKEHLALLAVPMVPLQIILPLLISKYTAGPQPLNIFYKAMPYR------------------------LLLGLEYALLVWWTPKVEHQGGFPLYYYIIVLLSYALHQVTLYSMYVSIMAFNAKVSDPLIGGTYMTLLNTVSNLGGNWPSTVALWLVDPLTVKECVGASNQNCRTPDA---IELCKKLGGSCVTALDGYYVESIICVLIGFGWWF-FLGPKFKKLQDEGPSSWKCKRNN----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6AYY8-1", "uniprot_id": "ACATN_RAT", "id": "Q6AYY8-1", "name": "Acetyl-coenzyme A transporter 1", "aln": "MSPTISHKDNSRQRRSGMFGHALDMKSGPLPPGGWDDNHQDSVGGEGDREVLLGDVGPGDFPKAKRS--YRAELSSILLLLFLYVLQGIPLGLAGSIPLILQS---KNVSYTDQAFFSFVFWPFSLKLLWAPLVDAVYFKNFGRRKSWLVPTQYILGIFMIYLSTQVDR------------LLGNIDGRTPDVVALTVTFFLFEFLAATQDIAVDGWALTMLSRENVGYASTCNSVGQTAGYFLGNVLFLALESADFCNKYLRFQPQPRGIVTLSDFLFFWGTVFLITTTLVALLKKETR---------------------------EASVVKEETQGITDTYKLLFSIIKMPAVLAFCLLILTSKIGFSAADAVTGLKLVEEGVPKEHLALLAVPMVPLQIILPLLISKYTAGPQPLNIFYKAMPYR------------------------LLLGLEYALLVWWTPKVEHQGGFPIYYYIIVLLSYALHQVTLYSMYVSIMAFNAKVSDPLIGGTYMTLLNTVSNLGGNWPSTVALWLVDPLTVKECVGASNQNCRTPEA---IELCKKLGGSCVTALDGYYVESIVCVLIGFGWWF-FLGPKFKKLQDEGPSSWKCKRTN----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O00400-1", "uniprot_id": "ACATN_HUMAN", "id": "O00400-1", "name": "Acetyl-coenzyme A transporter 1", "aln": "MSPTISHKDSSRQRRPGNFSHSLDMKSGPLPPGGWDDSHLDSAGREGDREALLGDTGTGDFLKAPQS--FRAELSSILLLLFLYVLQGIPLGLAGSIPLILQS---KNVSYTDQAFFSFVFWPFSLKLLWAPLVDAVYVKNFGRRKSWLVPTQYILGLFMIYLSTQVDR------------LLGNTDDRTPDVIALTVAFFLFEFLAATQDIAVDGWALTMLSRENVGYASTCNSVGQTAGYFLGNVLFLALESADFCNKYLRFQPQPRGIVTLSDFLFFWGTVFLITTTLVALLKKEN----------------------------EVSVVKEETQGITDTYKLLFAIIKMPAVLTFCLLILTAKIGFSAADAVTGLKLVEEGVPKEHLALLAVPMVPLQIILPLIISKYTAGPQPLNTFYKAMPYR------------------------LLLGLEYALLVWWTPKVEHQGGFPIYYYIVVLLSYALHQVTVYSMYVSIMAFNAKVSDPLIGGTYMTLLNTVSNLGGNWPSTVALWLVDPLTVKECVGASNQNCRTPDA---VELCKKLGGSCVTALDGYYVESIICVFIGFGWWF-FLGPKFKKLQDEGSSSWKCKRNN----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A4D6K3L8-1", "uniprot_id": "A0A4D6K3L8_DROME", "id": "A0A4D6K3L8-1", "name": "Acetyl-coenzyme A transporter 1", "aln": "MS--------AIRRKP--------------------------TGSNADQELLIDEPPKSEKVAEHQKPDIRGDRRNIAILLFLYVLQGIPIGLIAAIPMLLQN---RGASYKQQAEFSFAYWPFSLKLLWAPIVDSLYIRRFGRRKSWLVPVQYLLGAFMLLLSLHVDR------------WLG-GNGVDPNVPLLTLLFFLLNFLAATQDIAVDGWALTMLKRCNVGYASTCNSVGQTAGYFLGYVVFIALESKDFCNTYIRDVPLEDGMITLPRFLWFWGITFVVATTLVAIFKKENDIEDAH---------------------MDARYTEEHELNIHESYKILWDMVCMRPVQILAVILLTVKVTFAASDAVTSLKLIDAGVPKDKLALLAIPLIPLQLILPLAVGRYTNGPRPMDVYLKAIPYR------------------------IIMATVATGLAYITPYIVRGGAVPAYYYVLLITSYAIYQVFLYSMFVAAMAFFAKISDPAVGGTYMTFLNTLCNLGGNWPNTVVLWLVDVLTWKQCSNNAENTCQGKEE---QQSCEASAGKCEITFDGYYLESGICVLYGIVWLL-LVRKWIVYLQDLPVRSWLVVKQKSRXQSIV---------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38317-1", "uniprot_id": "YB69_YEAST", "id": "P38317-1", "name": "Uncharacterized protein YBR219C", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTLLNTLSNFGGTWPRLIIMSMINYFTVYQCTIPGTNKVYVTHGGSMQACTELLNGTVTILRDGYYITNLICIVVGLFLYFGYLKRKILHLQSLPISSWRFFHFFFTILAVTSRAIYYKSQNWRREC", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P38318-1", "uniprot_id": "YB70_YEAST", "id": "P38318-1", "name": "Uncharacterized membrane protein YBR220C", "aln": "-----------------------------------------------------------MEPKRKSGSLAKHDLPQFYLLIMLYLAQGIPVGLAFGTVPFLLKSLAKETSFTSLGIFSMATYPYSLKIIWSPIVDSLYNKRIGRRRSWIIPVQFVSGFVLWALGWCISQGIIFDGVDDAFHNRGNGTLHSVSIKNLTWWFGLLVFLCATQDIAVDGWALTILSKESLSYASTAQTIGLNIGYFMSFTIFLSLNSSDFANKYFRNIPLDHGFISLGGYMKFSGMLYIVITIYIIFCTKEKPYVEYLPKVEPINTSDGGSKPISIEYDDGDVVSTQNTSSIKYIYRCFIKVLKLKSVRSLAFIHMISKFAFQCNEAATNLKLLEQGFKREDLAVTVLIDLPFEIIFGYYVVKWSSDKDPMIRDNRRLRNSTGTNKVIKFLVGDAGVLTPWLWGFLGRLAAAVLGSYVVKQFPKDGEISTGYFCLVIFQHLLGSFMNTVQFIGISAFHTRVADPVLGGTYMTLLNTLSNFGGTWPRLIIMSMINYFTVYQCTIPGTNKVYVTHGGSMQACTELLNGTVTILRDGYYITNLICIVVGLFLYFGYLKRKILHLQSLPISSWRCT-------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **:***:.*:**.** : : ::: :* :* . :. . : *. ****: . :*:. *: : : : **. ** ", "identical_positions": 23, "similar_positions": 28, "identity": "3.57%" }, { "cls_id": "homologset.agr.MGI:1332623", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6ALT5-1", "uniprot_id": "A0A8I6ALT5_RAT", "id": "A0A8I6ALT5-1", "name": "", "aln": "MVSVVFSGLSGSSVMVPFLPILCCCCSCSATSPITPLLPFHDCLSISDFFHLASTCHTWAQKWRRFTAVLYGESGCALARLELQDGPE-------KTRRGEATRKVVRLSDCLRVAEVGSEASSPRDTSAFILETKERLYLLAAPSTERSDWIQAICLLAFPGQRKES-----PGLEEKNGSPCMEENELYSSS-TTGVCKEYAVTIRPTEASERCRLRGSYTLRTGVSALELWGGPEPGTQLYDWPYRFLRRFGRDKVTFSFEAGRRCVSGEGSFEFETRQGNEIFQALEKAIAAQKNATPS--------------------------GPPTLPATGS-------------------MMPTALP--------------------------RPESP--------YSRPHDSLPSPSPG--------------------TPVPGIRSGGS-----------------EGEYAVPFDTVVHS---------------------------------------------------LKKSFRGILTGPP--------------PLLPDPLYDSIQEDPVVPLPD-----------HIYDEPEGV-----AALSLYERSQKPSGETWREQATADGGTNSLQ------QDSSVSGWP--------------------------QVTEYDNVILKKGPK----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70469-1", "uniprot_id": "DOK2_MOUSE", "id": "O70469-1", "name": "Docking protein 2", "aln": "------------------------------------MVRMEEPAVKQGFLHLQ-QQQTFGKKWRRFAAVLYGESGCALARLELQDVPE-------KTRRGEATRKVVRLSDCLRVAEVGSEASSPRDTSAFILETKERLYLLAAPSAERSDWIQAICLLAFPGQRKGS-----PGLEEKSGSPCMEENELYSSS-TTGLCKEYMVTIRPTEASERCRLRGSYTLRTGVSALELWGGPEPGTQLYDWPYRFLRRFGRDKATFSFEAGRRCLSGEGNFEFETRHGNEIFQALEKVIAVQKNATPS--------------------------GPPSLPATGP-------------------MMPTVLP--------------------------RPESP--------YSRPHDSLPSPSPG--------------------TLVPGMRPGAP-----------------EGEYAVPFDTVAHS---------------------------------------------------LRKSFRGLLTGPP--------------PHLPDPLYDSIQEDPGAPLPD-----------HIYDEPEGV-----AALSLYDRTQRPSGETWREQATADGGPSSLQ------QDSSVPDWP--------------------------QATEYDNVILKKGPK----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60496-1", "uniprot_id": "DOK2_HUMAN", "id": "O60496-1", "name": "Docking protein 2", "aln": "---------------------------------------MGDGAVKQGFLYLQ-QQQTFGKKWRRFGASLYGGSDCALARLELQEGPE-------KPRRCEAARKVIRLSDCLRVAEAGGEASSPRDTSAFFLETKERLYLLAAPAAERGDWVQAICLLAFPGQRKEL-----SGPEGKQSRPCMEENELYSSAVTVGPHKEFAVTMRPTEASERCHLRGSYTLRAGESALELWGGPEPGTQLYDWPYRFLRRFGRDKVTFSFEAGRRCVSGEGNFEFETRQGNEIFLALEEAISAQKNAAPA--------------------------TPQPQPAT----------------------IPASLP--------------------------RPDSP--------YSRPHDSLPPPSPT--------------------TPVPAPRPRGQ-----------------EGEYAVPFDAVARS---------------------------------------------------LGKNFRGILAVPP--------------QLLADPLYDSIEET-LPPRPD-----------HIYDEPEGV-----AALSLYDSPQEPRGEAWRRQATADRDPAGLQHVQPAGQDFSASGWQ--------------------------PGTEYDNVVLKKGPK----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PZH7-1", "uniprot_id": "A0A8M1PZH7_DANRE", "id": "A0A8M1PZH7-1", "name": "", "aln": "---------------------------------------MEEDIRKKGMLYLQ--QQRFGKKWRKVWSVLYRESSCSISRLEFFEIKDGTPNTLEKANRKHENKKVIKMSDCIRVSEADVEG-CPRDCGPFLVETTEKTFVFAVETAELDDWIQKLCEIAFPMNWPEKGTMRGNSLHSEPDDATMADNTLYCSR--ETTMKDFKVTVRRSEASERCSLKGVVLLRTDTDSLLLKD-PKTGEVLYSWPYRFLRRFGRDKATFSFEAGRRCDSGEGSFEFDTKQGNAIFQSVEAAINLHRVNIPAKQMSNSDR--------------DLMPSPPRMRAPVENIGIYSMVSDTSIRDGAKPPQNPQLS--------------------------RLDAPTEKLLTGVKSLNLDTRPPPRKSQVKNFRSCPLANTEDEMYSRAMAPDPERGSPKEKRELKDRRSTCSNPEESDYSLPFDTIAKN---------------------------------------------------VMVDIFATTNFPPNAGESNCENNKKGTAENTEPLYDIIDESAIRSRFANKQTHSYKRVEHIYDEPEGCGVAPNAPPSLYDEPEEVKGHAWKMLGTVMDPSGHEYPYNASVDDYAVPKPPR------------RALLAKQMEGEEEDCSPYDNIMVKVMQKNN--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W3R6-1", "uniprot_id": "Q9W3R6_DROME", "id": "Q9W3R6-1", "name": "", "aln": "------------------------------MDVEIPVLAGYLNVPTQTGFSLN---RISKKKACSRYCLLFKASRHGIARLEMCESKE------------DRNPKIFTLENCVKITQE-----PPPERLIHIVKRQATLTLSTSSEEELKDWITALQTVAFCDTSPSG-----------GIGAIEEDNDLYCSS----FDGLFIITLIPSEASIRCCIEPKTYMLQMTPTELQLKSEDLGATIAMWPYRFIRKYGYRDGKFTFEAGRKCTTGEGVFTLDHTNPQEVFRCMSAKMKSMKKLISGDSLSTLECGENQFSAAAGMEPGSRSPLPPSPSSNPHGGEFEINSTQSCISLRGFISSNDSLNNFSAGGGGASGATATGGGVLGSTGGITLSVPANSNSNSSSSKHIPNKPPRKSPTTHCDKYRNIVKYEPVAITTISSPSANSDVN-SSVILKPLEGESISLPETAADLPPDLPLRNESASKAPPPERDYECIENITEAWRTRGVGDVRHSERMPILCDTSEFVRQRSVSKSTCGSQNTPKIIDIDIGEG-CTSATSISESNYDRLDFLSPNNKTSSG------YKTIVNVTPGNRIRCSPPPPNEYELIASPDTESFRKADDSHRGYGVLRKASTTTNNNNLGISNSNISGGSSTITTATANKGGNLEAAAIDHRSYNGLNYTMVSKPKRV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : * : :* . *: * .::***: : : . *:. :.:*::::: * : .::: : : * **: : :** . :* **.* : :*: :*** ** :. : : . * : *****:*::* . .*:*****:* :*** * :: : : :* .:. : : .. * : * . * * . *. * . * :* * :. : . . * .:. ** :: : * . .. . *: .::: :: *:.: . * ", "identical_positions": 61, "similar_positions": 98, "identity": "8.78%" }, { "cls_id": "homologset.agr.MGI:1332635", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P83565-1", "uniprot_id": "RM40_RAT", "id": "P83565-1", "name": "Large ribosomal subunit protein mL40", "aln": "MATAAMLCAARALRPRSWIPGTCQAQVRHTHQRASLLSFWELIPMRAEPLRKKKKVDP----RKDQAAKDRLKKRIRKLERASQELVPIEDFITPVRFLDKS--RQRPQEEHSFEESERRALLLKRWALYKQQEHEMERDAIRAMLEAQQEALEQLKLESTELYAEAIKRDTSLFPFEKEGPHYTPPVPNYQAPEGRYNDITKVYTQVEFKR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z2Q5-1", "uniprot_id": "RM40_MOUSE", "id": "Q9Z2Q5-1", "name": "Large ribosomal subunit protein mL40", "aln": "MATGVMLCAARALRPRSWIPGTCQAHVRHTHQRASLLAFWDLIPMRAEPLRKKKKVDP----RKDQAAKDRLKKRIRKLEKASQELIPIEDFITPVRFLDKS--RQRPQEEHSPEESERRALLLKRWALFKQQEHEMERDAIRSMLEAQQEALEELKLESAELYAEAIKRDTSLFPFEKEGPHYTPPISNYQAPEGRYNDITKVYTQVEFKR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NQ50-1", "uniprot_id": "RM40_HUMAN", "id": "Q9NQ50-1", "name": "Large ribosomal subunit protein mL40", "aln": "MTASVLRSISLALRPTSGLLGTWQTQLRETHQRASLLSFWELIPMRSEPLRKKKKVDP----KKDQEAKERLKRKIRKLEKATQELIPIEDFITPLKFLDKA--RERPQVELTFEETERRALLLKKWSLYKQQERKMERDTIRAMLEAQQEALEELQLESPKLHAEAIKRDPNLFPFEKEGPHYTPPIPNYQPPEGRYNDITKVYTQVEFKR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VGP7-1", "uniprot_id": "Q9VGP7_DROME", "id": "Q9VGP7-1", "name": "Large ribosomal subunit protein mL40", "aln": "-MSLLGAFARLSLQRSGGVAGAAFARCLHTTP-----------VLCAEPLKKKKKLDPQIVKQREDRKKKKIEKQIRRLEKNARQLKPVDELEVPLELIDEKDKRQRKLAPLTIDQLEERALLKKQWAHYKHDERVADFQIIDRLVQAQNKALAELRRESEELYQAAIDIDPQLLPVAVKGPVATPPIKDYVSPDGDYLHQSMKWEVK----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :*: . : *: :: .* : :***:****:** :::: *.:::::**:**: :::* *:::: .*:.::*: *:* : :: *.**** *:*: :*::*: : : * :::**::** :*: ** :*: **. *..*:*. :** ***: :* .*:* * . : : ", "identical_positions": 55, "similar_positions": 73, "identity": "25.94%" }, { "cls_id": "homologset.agr.MGI:1332637", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K7N9-1", "uniprot_id": "A0A0G2K7N9_RAT", "id": "A0A0G2K7N9-1", "name": "Rho GTPase-activating protein 5", "aln": "MMAKNKEPRPPSYTVSVVGLSGTEKDKGNCGVGKSCLCNRFVRSKADEYYPEHTSVLSTIDFGGRVVNNDHFLYWGDITQNGEDGVECKIHVIEQTEFIDDQTFLPHRSTNLQPYIKRAAASKLQSAEKLMYICTDQLGLEQDFEQKQMPEGKLNVDGFLLCIDVSQGCNRKFDDQLKFVNNLFVQLSKSKKPVIIAATKCDECVDHYLREVQAFASNK---KNLLVVETSARFNVNIETCFTALVQMLDKTRGKPKIIPYLDAYKTQRQLVVTATDKFEK-LVQTVRDYHATWKTVSNKLKNHPDYEEYINLEGTRKARNTFSKHIEQLKQEHIRKRREEYISTLPRAFNTLLPDLEEIEHLN---WLEALKLMEKRADFQLCFVVLEKTPWDETDHIDKINDRR-IPFDLLSTLEAEKVYQNHVQHLISEKRRIEMKEKFKKTLEKIQFISPGQPWEEVMCFVMEDEAFKYITEADSKEVYGRHQREIVEKAKEEFQEMLFEHSELFYDLDLNATPSSDKMSEIHTVLSEEPRYKALQKLAPDRESLLLKHIGFVYHPTKETCLSGQYCTDIKVENLLANSLLHSDHNRSR---LYHDSTNIDKVNLFILGKDGLAQELANEIRTQS-TDDEYALDGKIYELDLRPVDAKSPYILSQLWTAAFKPHGCFCVFNSIESLSFIGEFIGKIRTEASQIRKDKYMANLPFTLILANQRDSISKNLPILRHQGQQLANKLQCPFVDVPAGTYPRKFNESQIKQALRGVLESVKHNLDVVSPVPINKDVSEADLRIVMCAMCGDPFSVDIILSPFLDSHSCSAAQAGQNNSLMLDKIIGEKRRRIQITILSYHSSIGVRKDELVHGYILVYSAKRKASMGMLRAFLSEVQDTIPVQLVAVTDS--QADFFENEAIKELMTEGEHIATEITAKFTALYSLSQYHRQTEVFTLFFSDVLEKKNMIENSYLSD----NTRESTHQSEDVFLPSPRDCFP-YNNYPDSDDDTEAPPPYSPIGDDVQLLPTPSDRSRYRLDLEGNEYPVHSTPNCHDHERN--------------------------------------------------HKVPPPIKPKP-VVPKTNVKKLDPNLLKTIEAGIGKNPRKQTSRVPLAHPEDMDS-------------SDNYAEPLDTIFKQ------KGYPDEIYVVPDDSQNRIIKIRNSFVN-NTQGDEENGFSDRTSKGHGERRPSKYKYKSKTLFSKAKSYYRRTHSDASDDEAFPTSKTKRKGR------------HRGSEEDPLLSPVETWKGG-------------IDNPAITSDQEVDDKKIKKK-PHKVKEDKK-KKKTKTFN---PPTRRNWESNYFGMPLQDLVTAEK-PIPLFVEKCVEFIEDTGLCTEGLYRVSGNKTDQDNIQKQFDQDHNINLASMEVTVNAVAGALKAFFADLPDPLIPYSLHPELLEAAK-------------IPDKTERLHALKEIVKKFHPVNYDVFRYVITHLNRVSQQNKINLMTADNLSICFWPTLMRPDFENR-EFLSTTKIHQSVVETFIQQCQFFFYNGEIVETANTVAAPPTSNPGQLVESMVPLQLPPPLQPQLIQPQLQTDPLGII", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97393-1", "uniprot_id": "RHG05_MOUSE", "id": "P97393-1", "name": "Rho GTPase-activating protein 5", "aln": "MMAKNKEPRPPSYTVSVVGLSGTEKDKGNCGVGKSCLCNRFVRSKADEYYPEHTSVLSTIDFGGRVVNNDHFLYWGDITQNGEDGVECKIHVIEQTEFIDDQTFLPHRSTNLQPYIKRAAASKLQSAEKLMYICTDQLGLEQDFEQKQMPEGKLNVDGFLLCIDVSQGCNRKFDDQLKFVNNLFVQLSKSKKPVIIAATKCDECVDHYLREVQAFASNK---KNLLVVETSARFNVNIETCFTALVQMLDKTRGKPKIIPYLDAYKTQRQLVVTATDKFEK-LVQTVRDYHATWKTVSNKLKNHPDYEEYINLEGTRKARNTFSKHIEQLKQEHIRKRREEYISTLPRAFNTLLPDLEEIEHLN---WLEALKLMEKRADFQLCFVVLEKTPWDETDHIDKINDRR-IPFDLLSTLEAEKVYQNHVQHLISEKRRIEMKEKFKKTLEKIQFISPGQPWEEVMCFVMEDEAFKYITEADSKEVYGRHQREIVEKAKEEFQEMLFEHSELFYDLDLNATPSSDKMSEIHTVLSEEPRYKALQKLAPDRESLLLKHIGFVYHPTKETCLSGQYCTDIKVENLLATSLLEMDHNRVR---LYHDSTNIDKVNLFILGKDGLAQELANEIRTQS-TDDEYALDGKIYELDLRPVDAKSPYILSQLWTAAFKPHGCFCVFNSIESLSFIGEFIGKIRTEASQIRKDKYMTNLPFTLILANQRDSISKNLPILRHQGQQLANKLQCPFVDVPTGTYPRKFNESQIKQALRGVLESVKHNLDVVSPVPINKDVSEADLRIVMCAMCGDPFSVDLILSPFLDSHSCSAAQAGQNNSLMLDKIIGEKRRRIQITILSYHSSIGVRKDELVHGYILVYSAKRKASMGMLRAFLSEVQDTIPVQLVAVTDS--QADFFENEAIKELMTEGEHIATEITAKFTALYSLSQYHRQTEVFTLFFSDVLEKKNMIENSYLSD----NTRESTHQSEDVFLPSPRDCFP-YNNYPDSDDDTEAPPPYSPIGDDVQLLPTPSDRSRYRLDLEGNEYPVHSTPNCHDHERN--------------------------------------------------HKVPPPIKPKP-VVPKTNVKKLDPNLLKTIEAGIGKNPRKQTSRVPLAHPEDMDS-------------SDNYVEPLDTIFKQ------KGYSDEIYVVPDDSQNRIIKIRNSFVN-NTQGDEENGFSDRTSKGHGERRPSKYKYKSKTLFSKAKSYYRRTHSDASDDEAFTTSKTKRKGR------------HRGSEEDPLLSPVETWKGG-------------IDNPAITSDQEVDDKKIKKK-THKVKEDKKQKKKTKTFN---PPTRRNWESNYFGMPLQDLVTAEK-PIPLFVEKCVEFIEDTGLCTEGLYRVSGNKTDQDNIQKQFDQDHNINLASMEVTVNAVAGALKAFFADLPDPLIPYSLHPELLEAAK-------------IPDKTERFHALKEIVKKFHPVNYDVFRYVITHLNRVSQQNKINLMTADNLSICFWPTLMRPDFENR-EFLSTTKIHQSVVETFIQQCQFFFYNGEIVETANTVAPPPTSNPGQLVESMVPLQLPPPLQPQLIQPQLQTDPLGII", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13017-1", "uniprot_id": "RHG05_HUMAN", "id": "Q13017-1", "name": "Rho GTPase-activating protein 5", "aln": "MMAKNKEPRPPSYTISIVGLSGTEKDKGNCGVGKSCLCNRFVRSKADEYYPEHTSVLSTIDFGGRVVNNDHFLYWGDIIQNSEDGVECKIHVIEQTEFIDDQTFLPHRSTNLQPYIKRAAASKLQSAEKLMYICTDQLGLEQDFEQKQMPEGKLNVDGFLLCIDVSQGCNRKFDDQLKFVNNLFVQLSKSKKPVIIAATKCDECVDHYLREVQAFASNK---KNLLVVETSARFNVNIETCFTALVQMLDKTRSKPKIIPYLDAYKTQRQLVVTATDKFEK-LVQTVRDYHATWKTVSNKLKNHPDYEEYINLEGTRKARNTFSKHIEQLKQEHIRKRREEYINTLPRAFNTLLPNLEEIEHLN---WSEALKLMEKRADFQLCFVVLEKTPWDETDHIDKINDRR-IPFDLLSTLEAEKVYQNHVQHLISEKRRVEMKEKFKKTLEKIQFISPGQPWEEVMCFVMEDEAYKYITEADSKEVYGRHQREIVEKAKEEFQEMLFEHSELFYDLDLNATPSSDKMSEIHTVLSEEPRYKALQKLAPDRESLLLKHIGFVYHPTKETCLSGQNCTDIKVEQLLASSLLQLDHGRLR---LYHDSTNIDKVNLFILGKDGLAQELANEIRTQS-TDDEYALDGKIYELDLRPVDAKSPYFLSQLWTAAFKPHGCFCVFNSIESLSFIGEFIGKIRTEASQIRKDKYMANLPFTLILANQRDSISKNLPILRHQGQQLANKLQCPFVDVPAGTYPRKFNETQIKQALRGVLESVKHNLDVVSPIPANKDLSEADLRIVMCAMCGDPFSVDLILSPFLDSHSCSAAQAGQNNSLMLDKIIGEKRRRIQITILSYHSSIGVRKDELVHGYILVYSAKRKASMGMLRAFLSEVQDTIPVQLVAVTDS--QADFFENEAIKELMTEGEHIATEITAKFTALYSLSQYHRQTEVFTLFFSDVLEKKNMIENSYLSD----NTRESTHQSEDVFLPSPRDCFP-YNNYPDSDDDTEAPPPYSPIGDDVQLLPTPSDRSRYRLDLEGNEYPIHSTPNCHDHERN--------------------------------------------------HKVPPPIKPKP-VVPKTNVKKLDPNLLKTIEAGIGKNPRKQTSRVPLAHPEDMDP-------------SDNYAEPIDTIFKQ------KGYSDEIYVVPDDSQNR-IKIRNSFVN-NTQGDEENGFSDRTSKSHGERRPSKYKYKSKTLFSKAKSYYRRTHSDASDDEAFTTSKTKRKGR------------HRGSEEDPLLSPVETWKGG-------------IDNPAITSDQELDDKKMKKK-THKVKEDKKQKKKTKNFN---PPTRRNWESNYFGMPLQDLVTAEK-PIPLFVEKCVEFIEDTGLCTEGLYRVSGNKTDQDNIQKQFDQDHNINLVSMEVTVNAVAGALKAFFADLPDPLIPYSLHPELLEAAK-------------IPDKTERLHALKEIVKKFHPVNYDVFRYVITHLNRVSQQHKINLMTADNLSICFWPTLMRPDFENR-EFLSTTKIHQSVVETFIQQCQFFFYNGEIVETTNIVAPPPPSNPGQLVEPMVPLQLPPPLQPQLIQPQLQTDPLGII", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1R372-1", "uniprot_id": "F1R372_DANRE", "id": "F1R372-1", "name": "", "aln": "-MAKNKETR-PTYAVSVVGLSGTEKEKGNCGVGKSCLCNRYVRPSADCYYLEHTSVLSTIDFGGRVVNNDHFLYWGEVLHRGDDGVECRIQVIEQTEFIDDQTFLPHRSTNLQPYTKRAANTKLQSAEKLMYICTDQLGLEQDFDQKQMPDGKLNIDGFVLCIDISKGCNRKFDDQMKFVHSLYSQISKAKKPIIIAATKCDECVEQYLREVQTFVTGK---KNLMLVETSARASVNVELCFNALTQQIDKTRGKPKIISYLEAYKSQRQLVASVSDKFEKLIVQTVRDYHTSWKIVSNKLKSHPDYEEYINLEGTKKARNTFSKHIEQLRQEHIKRRREDYLTSLPKIFNKLLNNLEEIETMS---WTEAQSLMRSRHEFQYCFIELEHTPWYETDHLDKTDDRR-VPFDILQTMQGERIYQNHVQHLISEKRRLEMKEKFKKTLERVHFISPGQPWEEVMCFVMEDEAYKYITESDRRDVYSRHQQEIVERAKEEFQEMLFEHAELFYDLDLNATPSYDKMSEIHAVLNEEPRYRALQKLATDRESLLLKHIGFVYHPTKETCLSGTACIDLKVEQVLANRLVQLDHGRSN---IYYNSANIEKVNLCLVGREGLAQELANEIRAQS-TDDEYTLDGKIYELDLLPVDVNSGMLLNHSWISTFKPHGFFCVFSSIESLNYIGDRVSRIRAEIAQSRRDRYSQPVPFILILANQRDSVCKNMPILRHQGQQLANKLQCTFVDIPTGTFPRKFNESQIKQALRAVLEGLKHNFDMMSPMPSIKDLSETDLRIVMCAMCGDPFSVDLILSPFLDSHSCSAGQPGQCNTLILDKIIGNGRRRIQVTVLSYHSSIGIRKDELVHGYILVYSAKRKSSMAMLRAFLAEVQDVIPVQLVAITDS--QADFFENEAIKELMTEGEHIATEIAAKFTALYSLSQYHRQTEVFTPFFNEVLEKKSNIESSFMFD----NSRDGTGTTEDVFPQSPHSHSPAYQYYPDSEDDGEGPPPYSPIGDDVQLLPNPSER-KYRIDLEGNEYPIHSTP-VGEHERN--------------------------------------------------HKVPPPVKPKPNVLPKPNVKKLDPNLLRTIEAGMRTS--RWTRGPMMGHSDDLEA-------------SDNYAEPADTLQHKS-----KGYSDDIYAVPEDAHSRSGKTRNSFGGLVVHVDEENGFDS-MSKSQGGRRPSKYKHRSKILFSKTKAYHRRVHSDVSDDESGPATQKKKKGRG-----------NRGSEEDPLLSPVDPWKGG-------------IDNPAITSDPEQDERKTKKKKAPKTKEPKKPTRSTKTTKPLYPPTRRNWESNYFGVPLQNLVTPDR-PIPLFVEKCVDYIERTGFTTEGLYRVCGNKTDQDNIQKQFDQDHSIDLIVMDVAVNAVAGALKAFFADLPDPLIPYSLHPELVEAAK-------------IVDHYERLQVLKEIVRKFPPVNYEVFKYVITHLNRVSQHSKTTLMTADNLSICFWPTLMRPDFENK-DTLSTTKLNQSVIESFIQQCQYFFYGGDMTEPSSAEGTPPPHGHG--LESLLALQLPPPLQPQQIQHPLPPEPLI--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VX32-1", "uniprot_id": "RG190_DROME", "id": "Q9VX32-1", "name": "Rho GTPase-activating protein 190", "aln": "---------MRQFNISVIGLSGTEKDRGQVGVGKSCLCNRFMRPMADDYFIDHISVLSQSDFSGRIVNNDHFLYWGDVRKTTEEGVEYQFNIIEQTEFMDDSTFQAFKVGKMDPYSKRCTATKVFSAEKLMYICKNQLGIEKEYEQKVMPDGRLSIDGFVVVFDVSPVPNRSVEKQVEFVQNVIATILKNKKPLVLVTTKNDDAYELYVREAEKISQRKDYKSTVQLIETSAHESINIDLAFLLLAQMIDKVKNRVKIISYQESAKSRKELLDTRSEAVTRLIRNQITDYHVLWSQGSKMLSQYREWNEFLNIFGHEAGQKLFRRHMKKLRDDHLNKKLHQYLDKFALALEYLLPDIGALNISDDDAWECARNYLQNHIEFEQYFFECPQASWTELVDMDEAEDEARIPFDVLETSEAETVFRNYLNSVQQDKKKIGWKQQFKMLLEESGFVTPGKQLSEVRVLFMGRECFEALSEHDCQQIYDIHQDDIIEKSKQNFVELLLEHAQYFLQFKNVDNITQEDVRQITDVIQEDSRYKMLDRLDQERRLMLVQHLRFIHCPIRDHCPFFYNCVDSLIEEVLSDKSASNHKTPSGGGWKSSGSGSDRTLNLLIVGSEHLASDLLNDIRICTGSKGEYIYENQTYYLNYRIANGD----MEAFKAIDVYSSGLICVYSNQQSFETLKDNLERT--LLCNLELEDKFENLPIVLVYQPQ-DLKENEVEYLRNEGMRLSEMLHCDFIDHTQNHQKYVYDILNIVILSLKLTEMKSYEPYPSN---------HTDLRILCCIFCGDQYDIENIVQPLVEESTLVKAN---EHSIIVDVFIGDAKRRVEFILSSYHGTSQYR-DELIHGYIYFYSTKRRSSLANLSILAAQNAN-IPLQIIAVTESGGVNAFFNSDICQFLITEGNAVADRFKGSFMTFS--ADQYVKFAFYNPFLKTAWDNKYEVENLHVEESITLDSGEGTLENSVNQMPRPPPRHESYMLSNTLGTDGSGSENYEMAPTRSLNSLNEERDISLDEIYDDNEKPKHLHQKWLEDKSDGRRNMNKNLIWNNFSGSTHAYTTGRRHIDSNLNKIRPKGPSQTLKVGEAPSRNCPAMSSSTFTLPTQQPGKLNMKNFQLVSDAVAKMNFTGSGSGSGSGSGSGSTGLGLGLGSGSGCMGDSFLEPVDKDGKRYDHAQLDGEDEDSEELAEYEQIYENEDCTESDSCASSTERRVRQQNAYYKASKKPVAAKKQKKKKVAIPVQTPRVPPFGSYVSPPEIPLHYQRMAVGGSGPEKPEPCVPEFMKSDKSPEYSMVPELAGAGIFGAENLPEYNMNQAKCLKDFEKLEKRRIKEETARQRKLQEKEKEQEKKLKRKLKQNAKGLVESAEAQFGKLMITSEQGEIPIFLNKCVEFIEKEGLDSEGIYRVPGSRAHVDMLFQRFEEDTNTEIDALDIPVNAVATALKDFFSKRLPPLFSKDIIKELEEIAGSRGVGNSKLNVEVKTDRSCRLIALKSLLQKLPPINFAILKYIFQHFVHVSDNSKLNSMDSKNLAICWWPTLIPIDFTDMGHFEQLRPYLEDIVQTMIDQFPYLFCGKDAFVMV--------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :*::*******::*: **********::*. ** *: :* **** **.**:**********:: : ::*** ::::******:**.** ..: :::** **.: :*: *********.:***:*::::** **:*:*.:***:: :*:* **..:.*::**:.: : * ***:::.:** *:. : *:**.: : * ..: ::****: .:*:: .* *.* :**.:.: ***.* :: *::::*: : :: . : : : : ***. *. *: *..: :::*::*: * . .:: * :*:::*:::*:.:: .:*: .:. :: ** :: :: . * * . :..: :*: *. ::.* * .:*: :*. :***:*.* :.* :::*::: : .:*::: *::** **. *::**: .** :.* *.:: ::* * :::*. ** :*:*::*::* *:*:**:: * ::. . : :.: :* *:.*:.**: *::* :*. :*::*: *:: * :: * * * :*::*: .: .* . .:** ::* : **.:* *:** : :..** :.: * *: .: . :. . . * :**:.. :*:. : : : : .: . : :*: *: * * ::: **::* :*:: *:* *:* . . :: :* : * .:: . .:****: * :*** :.:: *:.*:::. : .: :::::* :**: :**::. : ***.: * ***:**** .**:**::*:. * : :: : **:*::*:*:* **:.: : *:***: :* .: ..* :: :: : : .:. *:. . ::* :*. .: : :: :.* .. * * * ... *. . . :.** * * :.: : : *.:.... .:*. : **: : :: :. .: . : . . . .. .*.: ** *. :: .* :: :.: : : .. . :.. .. *. .:* : :.* :. .. * .* * : * *::.* * * *. : .:.. : :.:: *:: . : * :* ... *. : . :. .. . : ::*.:: **:*::***::** *: :**:*** *.::. * : ::*::* . :: :::.***** *** **:. **:. .: ** * * *: *: .**.:::*: *:*: :::*:: *: :**:: * . * :.**:**:****: ** : . . :.:::::*:* ::* . : ", "identical_positions": 367, "similar_positions": 562, "identity": "22.42%" }, { "cls_id": "homologset.agr.MGI:1332638", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZPR7-1", "uniprot_id": "A0A8I5ZPR7_RAT", "id": "A0A8I5ZPR7-1", "name": "Protein Wiz", "aln": "----------------MEGLLAGGLAAPDRPRGPERLPGPAPREDIEGGAEAAEGEGDIFRSSHYLPITKEGPRDILDGRSGISDGQPHPGLSEALPRATSATHRISSCYWDGDSLDFQPGSPPPHLLGPFPASFDVQGSWEHPMVQEAREGTPSEQRFKDSVIVRTMKPYAKLKGSRKFLHHQGELKFLEKYFPSHHKFDWLQDTDEQGLLKDTGLHLDLPAQPPNVTSFRRVIVPVDDTPKTLDTEVMGTREDLEDFGEVAQPSEWGLHTSASEVATQTWTVNSEASVERLHPLLSPVQTEPYLCELLQEAAGGVDS-HEEEEEEPAVFPCIECSIYFKHKEHLLEHMSQHRRAPGQEPP------------ADLAPLACSECGWAFTEPTALEQHWQLHQASREKIIEEIQKLKQFPDDEGREARLQCPKCVFGTNSSRAFMQHAKLHVRESLPSRQAKEPFRG----GSPVLDVSTLVYPSYGDSSGLNTCVHCGFTAPSKSLLREHMRLVHAQ-AHWEEDGEAF-EDLTGQPGTSQDAYTHLPDTATMDCFSKSEPLLASVWQDNPSGYDPGLAFGPEYQQPGMRDFPLLN-----SGERSLGKLAFPSSPVPSASYSIQLSRDKSTVHLQRMEDKSPPWSGEEE----DEDGVLTPEMDCTPENGAFPPPAIPSLIPQPALELKQTFRDALQAVSASETQQWQLRRMVPIVLMAKLRPQVIAAAARASPRLPPEELELRSTHPLDFLLLDTPLGSSLGLDTFLEGEPAMALKHEERKCPYCPDRFHNGIGLANHVRGHLNRVGVSYNVRHFISAEEVKAIERRFSFQKKKKKVANFDPGTFSLMRCDFCGAGFDTRAGLSSHARAHLRDFGITNWELTISPINILQELLATSAAELPPSPLGREPGGPPGSFLTSRRPRLPLTMPFPPTWAED--------PGPVYGDGLCSEENTMVAMDLGSSLLPKKSLPVSGTLEQVASRLSSKVAAEVPQGSKQELPDLKAQSLTTCEVCGACFETRKGLSSHARSHLRQLGVAESESSGAPIDLLYELVKQK--------------------------------------------------GLPDAPLGLPPNLTKKSNSPKEFVAGAARPGLLTLAKPMDAPAVNKAIKS--------------------------------------PPGFSAKGLTHPSSSPLLKKAPLTLAG---------------------------SPTPKNPEDKSPQLSLSPRPTSPKAQWPQSEDEGPLNLTLDSDGGRELDCQLCGAWFETRKGLSSHARAHLRHLGISDPDAKGSPIDVLHGLIRRDGIQIRLPPGRGALAQLGRPPSTSTALSLLPPPPPAKKAKLKASGMASPWGKQDLSAAGIFWASDVEPSPLNLSSGPEPTRDIRCEFCGEFFENRKGLSSHARSHLRQMGVTEWYVNGSPIDTLREILKRRTQSRPGGHLHPPGPSPKALAKMVGSAGPGSSLEARSPSDLHISPLAKKLPLPPGSPLGHSPTASPPPTARKMFSGLATPSLPKKLKPEHMRVEIKREMLPGALHGEPHPSEGPWGAPR-EDMAPLNLSSRAEPVRDIRCEFCGEFFENRKGLSSHARSHLRQMGVTEWSVNGSPIDTLREILKKKSKLCLIKKEPPAGDLAPALTEDGSPTAAPGVMHSPLPLSPLATRPGKPGAGPTQVPRELSLSP--ITGSKPSATSYLGPVATKRPLQEDRFLPAEVKAKTYIQTELPFKAKTLHEKTSHSSTEACCELCGLYFENRKALASHARAHLRQFGVTEWCVNGSPIETLSEWIKHRPQKVGAYR-SYIQGGRPFTKKFRSAGHGRDSDKRPPLGLAPGGLSLVGRSAGDEPGPEAGRAADSGERPLATS-------------------PPGTVKSEEHQRQNINKFERRQARPSDASAARGGEEANDLQQKLEEVRQPPPRVRPVPSLVPRPPQTSLVKFVGNIYTLKCRFCEVEFQGPLSIQEEWVRHLQRHILEMN------------------------------FSKADPPPEEPQAPQAQTAAIEAP----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88286-1", "uniprot_id": "WIZ_MOUSE", "id": "O88286-1", "name": "Protein Wiz", "aln": "----------------MEGLLAGGLAAPDHPRGP------APREDIESGAEAAEGEGDIFPSSHYLPITKEGPRDILDGRSGISDGQPHPGLSEALPRATSATHRISSCYWDGDSLDFQPGSPPPHLLGPFPASLDVQGSWEHPMVQEAREGTPSEQRFKDSVIVRTMKPYAKLKGSRKFLHHQGEVKFLEKYSPSHHKFDWLQDTDEQGPLKDTGLHLDLPAQPPTVTSFRRVIVPVDNTPKTLDMEVMGTREDLEDFGQVAQPSEWGLHTSASEVATQTWTVNSEASVERLQPLLSPVQTGPYLCELLQEVAGGVDS-NEEEEEEPAVFPCIECSIYFKHKEHLLEHMSQHRRAPGQEPP------------ADLAPLACSECGWAFTEPTALEQHWQLHQASREKIIEEIQKLKQFPGDEGREARLQCSKCVFGTNSSRAFMQHAKLHVRGSLPSRQATEPFRG----GSPVLDVSTLVYPSYGDSSGLNTCVHCGFTAPSKSLLREHTRLVHAHHAHWEEVGEAF-EDLTSQPCTSQDAYTHSPDTATVDYFSKSEPLLASVWQENPSGYDPDLAFGPDYQQPGMRNFPLLN-----SGQQSLGKLAFP-SPMASASYSIQRNRNKSTVHLQRMEDKSHLWSEEEEEE--DEDVVLTSERDFTPENGAFPPLAIPSLIPQPALELKQTFQDALQAVDASETQQQQLQGMVPIVLMAKLRPQVIAATTRASPQLPPEEPELRSTHPLDFLLLDAPLGGSLGLNTLLEGDPAMALKHEERKCPYCPDRFHYGIGLANHVRGHLNRVGVSYNVRHFISAEEVKAIERRFSFQKKKKKVANFDPGTFSLMRCDFCGAGFDTRAGLSSHARAHLRDFGITNWELTISPINILQELLATSAAELPPSPLGREPGGPPRSFLTSRRPRLPLTMPFPPTWAED--------PGPIYGD---------------------------------------------------------AQSLTTCEVCGACFETRKGLSSHARSHLRQLGVAESESSGAPIDLLYELVKQK--------------------------------------------------GLPDAPLGLTPSLTKKSNSPKEFLAGAARPGLLTLAKPMDAPAVNKAIKS--------------------------------------PPGFSAKGLTHPSSSPLLKKAPLTLAG---------------------------SPTPKNPEDKSPQLSLSPRPTSPKAQWPQSEDEG----------------------------------------------------------------------------------------------------------------------------------PLNLTSGPEPTRDIRCEFCGEFFENRKGLSSHARSHLRQMGVTEWYVNGSPIDTLREILKRRTQSRPGGHLHPPGPSPKALAKVLSTGGPGSSLEARSPSDLHISPLTKKLPPPPGSPLGHSPTASPPPTARKMFSGLATPSLPKKLKPEHMRVEIKREMLPGTLHGEPHPSEGPWGTPR-EDMAPLNLSARAEPVRDIRCEFCGEFFENRKGLSSHARSHLRQMGVTEWSVNGSPIDTLREILKKKSKLCLIKKEPPAGDLAPALTEDGSPTAAPGALHSPLPLSPLASRPGKPGAGPTQVPRELSLSP--ITGSKPSAASYLGPVATKRPLQEDRFLPAEVKAKTYIQTELPFKAKTLHEKTSHSSTEACCELCGLYFENRKALASHARAHLRQFGVTEWCVNGSPIETLSEWIKHRPQKVGAYR-SYIQGGRPFTKKFRSAGHGRDSDKRPPLGLAPGGLSLVGRSAGGEPGLEAGRAADSGERPLATS-------------------PPGTVKSEEHQRQNINKFERRQARPSDASAARGGEEVNDLQQKLEEVRQPPPRVRPVPSLVPRPPQTSLVKFVGNIYTLKCRFCEVEFQGPLSIQEEWVRHLQRHILEMN------------------------------FSKADPPPEEPQAPQAQTAAVEAP----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95785-1", "uniprot_id": "WIZ_HUMAN", "id": "O95785-1", "name": "Protein Wiz", "aln": "----------------MEGSLAGSLAAPDRPQGPERLPGPAPRENIEGGAEAAEGEGGIFRSTRYLPVTKEGPRDILDGRGGIS------------------------------------GTP------------DGRGPWEHPLVQEAGEGILSERRFEDSVIVRTMKPHAELEGSRRFLHHRGEPRLLEKHAQGRPRFDWLQDEDEQGSPQDAGLHLDLPAQPPPLAPFRRVFVPVEDTPKTLDMAVVGGREDLEDLEGLAQPSEWGLPTSASEVATQTWTVNSEASVERLQPLLPPIRTGPYLCELLEEVAEGVASPDEDEDEEPAVFPCIECSIYFKQKEHLLEHMSQHRRAPGQEPP------------ADLAPLACGECGWAFADPTALEQHRQLHQASREKIIEEIQKLKQVPGDEGREARLQCPKCVFGTNSSRAYVQHAKLHMRE-PPGQTTKEPFGGSSGAGSPSPEASALLYQPYGAAVGLSACVFCGFPAPSESLLREHVRLVHAH-PHWEEDGEAYEEDPASQPGTSQDAHACFPDTA-VDYFGKAEPSLAPMWRENPAGYDPSLAFGPGCQQLSIRDFPLSKPLLHGTGQRPLGRLAFP-STLASTPYSLQLGRNKSTVHPQGLGERRRPWSEEEEEEEEEEDVVLTSEMDFSPENGVFSPLATPSLIPQAALELKQAFREALQAVEATQGQQQQLRGMVPIVLVAKLGPQVMAAAR-VPPRLQPEELGLAGAHPLDFLLLDAPLGGPLGLDTLLDGDPAMALKHEERKCPYCPDRFHNGIGLANHVRGHLNRVGVSYNVRHFISAEEVKAIERRFSFQKKKKKVANFDPGTFSLMRCDFCGAGFDTRAGLSSHARAHLRDFGITNWELTVSPINILQELLATSAAEQPPSPLGREPGGPPGSFLTSRRPRLPLTVPFPPTWAED--------PGPAYGD---------------------------------------------------------AQSLTTCEVCGACFETRKGLSSHARSHLRQLGVAESESSGAPIDLLYELVKQK--------------------------------------------------GLPDAHLGLPPGLAKKSSSLKEVVAGAPRPGLLSLAKPLDAPAVNKAIKS--------------------------------------PPGFSAKGLGHPPSSPLLKKTPLALAG---------------------------SPTPKNPEDKSPQLSLSPRPASPKAQWPQSEDEG----------------------------------------------------------------------------------------------------------------------------------PLNLTSGPEPARDIRCEFCGEFFENRKGLSSHARSHLRQMGVTEWYVNGSPIDTLREILKRRTQSRPGGPPNPPGPSPKALAKMMGGAGPGSSLEARSPSDLHISPLAKKLPPPPGSPLGHSPTASPPPTARKMFPGLAAPSLPKKLKPEQIRVEIKREMLPGALHGELHPSEGPWGAPR-EDMTPLNLSSRAEPVRDIRCEFCGEFFENRKGLSSHARSHLRQMGVTEWSVNGSPIDTLREILKKKSKPCLIKKEPPAGDLAPALAEDGPPTVAPGPVQSPLPLSPLAGRPGKPGAGPAQVPRELSLTP--ITGAKPSATGYLGSVAAKRPLQEDRLLPAEVKAKTYIQTELPFKAKTLHEKTSHSSTEACCELCGLYFENRKALASHARAHLRQFGVTEWCVNGSPIETLSEWIKHRPQKVGAYR-SYIQGGRPFTKKFRSAGHGRDSDKRPSLGLAPGGLAVVGRSAGGEPGPEAGRAADGGERPLAAS-------------------PPGTVKAEEHQRQNINKFERRQARPPDASAARGGEDTNDLQQKLEEVRQPPPRVRPVPSLVPRPPQTSLVKFVGNIYTLKCRFCEVEFQGPLSIQEEWVRHLQRHILEMN------------------------------FSKADPPPEESQAPQAQTAAAEAP----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "I3ITC3-1", "uniprot_id": "I3ITC3_DANRE", "id": "I3ITC3-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MENTAVDTAKTSTATFSKE----PLVSEVHKDESDSG-------------------------------------------------------IHSCEFCGTNFETRPGLSSHARFHLRQLGVAVSDSSGAPIDLLSKLMK-----ERGGTLPKFKKQAKPVKKYKHKSQVKAKPAKKSKLPSHILKKKPGPKLKIKISNIVKKKYALSSSS---APSAVKGSLAGLTFAVGKTSKKSSKKIVVSSPVASS--------LPKALESRIGDSSPSTSLSLASAKPLWAPQETDAPLNLTTMTN-------------------STKREDVHVCELCGAWYETRKGLSSHARSHLRQFGVHLDSKG-APIELLHKIIQSEDFQEKASAG----------------------------------LLDIPDIKDRTSLTSVPSTSSSTSKNPSPSSLVLKGLTSIRIIPPSVKKQKTSLDVS--------------------------------------GNLLSKKAQFKSTVSAKKKKISQDFSG----------------NMPLSGQTELKSPSRKKKKLSPDVLSILPVSGKAE-SKSSPPAKKQKVSADVSEALPLIEKTELKSTPSVKKCKISSDASASLSLG--------------------------------------------------------------------------------------DQAEFKSRCHGESSKTVKCDFCHEKFKKSQSLASHARYHLRQLGITEWSVKGSPMATLREVMAQR----------AASAGS------LSTLEPPSLTPLLSPSATPSAPPLLLAPEPPSS--SPRPVPHKVPKAKKG-----FRTVNPKPKDEPVEVDVSNIESSKSQSAPITPLTPLSDSNAVKSPVIAAKTENQEPKQFVCCDYCGEMFDTRKALSCHARSHLRQLG-AKWSLKFPPIEALHELMRREGT---VRASQIK-------------------PESALG------------------------------------------------------APVQIKKKAITPPKLTLSPVENKKPEDGAGCDATCELCGFDFENRKALASHARAHLRQQ-GVDWKVHGSPIETLMAWMKSEPQKVAELHKSYMRGQLPFVKKVPRKTSTPYSSSDSESVRLGSPKASSKDSAGQPQVSQNSKAARDGKAGMSHYSTHKKR------------PPSDELSSDSLIQSPTARSELNVRLPRGFERRPTKHSSHSESRSGETEPSKPPRVGNIPSLVPRPPETSLVKLVGKIYSLKCRFCEEVFHGPLSIQEDWVMHLQQHILKLK---------------------------QDSGSSAQPPLSQPETPLLIGPQAV------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M3AQA7-1", "uniprot_id": "A0A8M3AQA7_DANRE", "id": "A0A8M3AQA7-1", "name": "", "aln": "MEPEDDLSTGDPQDLMSSQALLPSTSTSLLNCSFLGELLNCDDIEKGDGSGDPEGPNCFFTTLENCDKTQKNLRSSAFPSSLTWDSDSEKEILDEEDLQHFSNPHGLAAHSPGCPTSGQHQERFDSDLCQEPVETEHLFLEKVPLAPLEVENQDDVTCKEPRSSDSSLLKHTAKRKIKTLMEQDKVSSLPGTMP--KKVCQKEDKDKRKVLNRKGQEEEEKSTKEADVYTFPGDSEPESPPPGPWAHCTFIQRRRKKRAILRPFSGLGNCQQTTGTGKRTRGRPPGKGRNKTTKDRQAMLEFTEEKTEKVRRRQKAVVEQPPDGSLSQDIFTCVECSIYFKKRTHLWEHMQEHGQVNRSGQKWQSGEKEAWSGHLNKKAFECIECGQEFLDKVLLLDHNQRHEDSRQKILEEIGKLSEG--DKRVAEQASCSNALEPVIQEPAKVSGGQLVCLKCNFSTDVPQELSEHAKTHTTRKRAGVYRTSPRFQQRSCKKAQVQSSADITPTDNTSPPNKRYPIRASKKNKETQPSVGSSQDPCQSASAATGKEDTDQPVKANLQANTDSAEESRKTEEPTVDIPIQENVLELQHLILPSSN------PRTVPRRKDVAFKSIGNKRGRGGRGRRRGSTRLDYRSNLNTGVKTQVQISNQTEYMGHKEDNPTTEPEDDQTQVSKTGKESPATVLNLKASSSTPKKSSKKLVAD----DEEPKLRKDKSNSPGKIEENTAVPEKIVMEEYDDDEYEDDEDVVSRLIGALTEEDDDDDDDRDGLLKSVERKCPYCPDRFHNGIGLANHIRGHLNRVGVSYNVRHFISPEEVNAIEKKFSYQKKKKKVANFDPSTFSVMRCEFCSAGFDTRAGLSSHARAHLRDFGITNWEVTVSPINILRQLFAKHPNLVLPTASTHTLQSSPEQNSDEEQESRKDMKDEDDMTAEPDTFSSVFLKQCWKEEHDISEPEGGEGAEDDEEEDDDDETQMPLTDKLSTSPGHKTLFSLDEESPESKDTDPRGSNLLKCSVCGATFETRRGLSTHSRSHLRQPGMGMSENSRAPIDLLYQATKHHSRDAQSPTKRKQHVPVVPVPSPMKDIETEEGLSDTKPPVMFSAIKVSPSPTTPSTAGSLPSSPFVKSRSPSPVLRKAPISSLLPVSSPLRSQEHKILGKSQSTNPSGPTKPFWAPQDTDAPLNLTMDMDSKDIICQLCGAWFETRKGLSSHARAHLRHFGIEYSESKGSPIDLLNRFILTDDFKHRANSFLSDGPEDLRSQKTSITSLLPSTSSSKRPLPSSPVLYKTAASPLKTTIGSKATSSTHTLLGPPKKKLKPSALQVLRFS--------------------------------------------------------------------------------------DGEMMS--FPIEPLKDVSCEFCGELFENRKGLSSHARSHLRQLGITEWSVNGSPIDTLKEIIVRRGLPTIMPLKSPKSPSS------PSPGLPRHMLQSSSPSGNIIGRLPFHFAKTPNH--DQPAIHKMSPSTSTTSSPPIVDLVKPKPEPEIVEVTMKGSDMGADEHYSPEPLHSSLISSDNVYPVNLVMTQEKEPSRDIRCEFCGEFFENRKGLSSHARSHLRHMGITEWSVNGSPIDTLWEVMRRQGS---TPASVALGIKEEPGQDGRISLSSPGYQTSALSRKSPLNLLHSGSRLHKHGLGSIGLSPALPVGKLFGVLPLKKKVLVEEKHPGEKTLLVQSKDFSSPPQDYSFKGKTSAEKHGVGQMDPSCELCGFYFENRKALASHARAHLRQFGVTEWCVNGSPIETLSAWIRSRPQKAAEMQQSYAQGVRYAQKKRCSSVVSPSCDSDPTTPVSQKPTVAKWASLTLPQKRAIGRDANSCSWGLSSRGADAKSRSASSTQHGLIPQPAGHHSNNALPHAQVAHSELNVRLPRGFERRPLKHPSHAEGGEGESGPPKP-RSSTVPALVPKPPSTPLVRLVGKIYSLKCRFCDVEFHGPLSVQEDWIRHLQQHILNLNYKKTEPPANDSPAQSDTPAPKPQVSAATSTSTASTIPAAAPSTPSPKSPTATHASASTLSQASTAPSPAN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: .: : . : . : : . :.* :* .*. **:.* * **.::**: . . : :. : : :: .:.:*. : .: : .. . . * *. . *:. .: ::.:* * : ::. . *:. . . : :. ..: *.:*** :***:***:*:****** *: .... ***:**:: : . : .:.. .* . . : : * . * :. : . . :: : . . . . .. *: * . ..: ... :. *. : : *:** * *:: :.*:**** ****:*:*** *:***: **:*:: :* . .... . * *** . . .*. . . *.: . : * : * :.* :. * : . : . ** : : *::***:*:.**.**.*******::* ::**:: .**::* *:::::.. . *.* .: * : . .:. : . . :. *****: ***************** .:* *:******* *:: .***.. : ** :* ** ... . * .: * . . :: *.. . : : : * . * . . . : . * * * :*:***:**.*.**::**:**:******: *:****:**:*: ***:***::: : : * ..:* . ", "identical_positions": 194, "similar_positions": 258, "identity": "9.19%" }, { "cls_id": "homologset.agr.MGI:1332659", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O60238-1", "uniprot_id": "BNI3L_HUMAN", "id": "O60238-1", "name": "BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like", "aln": "MSSHLVEPPPPLHNNNNNCEENEQSLPPPAGLNSSWVELPMNSSNGNDNGNGKNGGLEHVPSSSSIHNGDMEKILLDAQHESGQSSSRGSSHCDSPSPQEDGQIMFDVEMHTSRDHSSQSEEEVVEGEKEVEALKKSADWVSDWSSRPENIPPKEFHFRHPKRSVSLSMRKSGAMKKGGIFSAEFLKVFIPSLFLSHVLALGLG--IYIGKRLSTPSASTY-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Z2F7-1", "uniprot_id": "BNI3L_MOUSE", "id": "Q9Z2F7-1", "name": "BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like", "aln": "-MSHLVEPPPPLHNNNNNCEEGEQPLPPPAGLNSSWVELPMNSSNGNENGNGKNGGLEHVPSSSSIHNGDMEKILLDAQHESGQSSSRGSSHCDSPSPQEDGQIMFDVEMHTSRDHSSQSEEEVVEGEKEVEALKKSADWVSDWSSRPENIPPKEFHFRHPKRAASLSMRKSGAMKKGGIFSAEFLKVFIPSLFLSHVLALGLG--IYIGKRLSTPSASTY-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AKI3-1", "uniprot_id": "A0A8I6AKI3_RAT", "id": "A0A8I6AKI3-1", "name": "", "aln": "-MSHLVEPPPPLHNNNNNCEEGEQSLPPPAGLNSSWVELPMNSSNGNGNGNGKNGGLEHVPSSSSIHNGDMEKILLDAQHESGQSSSRGSSHCDSPSPQEDGQIMFDVEMHTSRDHSSQSEEEVVDGEKEVEALKKSADWVSDWSSRPENIPPKEFLFRHPKRAASLSMRKSGAMKKGGIFSAEFLKVFIPSLFLSHVLALGLGNKTRVERDTIVHLLQQLK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VPD6-1", "uniprot_id": "Q9VPD6_DROME", "id": "Q9VPD6-1", "name": "", "aln": "----MSTTPKSSEDLLGESWIELSTTAAMAGIKSPDRITPLPFNNGEEYLRLLREAQRESNQSSRVVS--LASSRRDTPRDSPKSPP--NSPQSELCPDDELRNVYINYWTKGGDKQNAGNEDWLKNWN-----QPPSSWNIEDSSRD---AGDEGEKKKTNTGYSIRLKRLGSN---SLFSREILYSLLVTNVLSLLLGAGFG--LWLSKRGILLTRVVID", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .* . .: .:. .. .. **::*. *: .**: . . . .. .** : . : . *: ::* :*.. .* .. .*::: : :: .. *:.. .:*: :.. : : .:.* : *** . .* ::.: . *: ::: *: .:** *:* :: : .** :*. *:* : : ", "identical_positions": 32, "similar_positions": 85, "identity": "14.41%" }, { "cls_id": "homologset.agr.MGI:1332671", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M8G0-1", "uniprot_id": "PHTF1_RAT", "id": "F1M8G0-1", "name": "Protein PHTF1", "aln": "MASNERDAISWYQKKIGAYDQQIWEKSIEQTQIKGFKNKPKKMGHIKPDLIDVDLIRGSTFAKAKPEIPWTSLTRKGLVRVVFFPLFSSWWIQVTSLRIFVWLLLLYLMQVTAIVLYLMMP-------------------------------------IVSVSEVLGPLCLMLLMGTVHCQIVSTQITR-PSGNNGNRRRRKLRKTVNGD--GTRDNGNNSPDKIRAVETLDSAPSVGGFWGTLFGNRIKR----------------------------------VKLVSNKGTETDNDSGCFHPIIKKRQGRPEIRMWQAREKAKVSDGEKCRREAYRR---------LGNGVSDDLSSEEDGEARTQMILLRRSVEGASSDNGCEVKNRKSILSRHLNSQVKKTATRWCHIVRDSDSLAESEFESAAFSQGSRSGMSGGSRSLN--LSRRDSESTRHDSETEDMLWDDLLHGPECRS------------SVTSDSEGAHVNTLHSGTKRDPKEDVFQQN-------HLFWLQNSSPASERVSAIIWEGNECKKMDMSVLEISGIIMSRVNAYEQGVGYQMLGNAVTIGLALFPFLYRLFREKS---FDQLKSISAEEVLTLFCGAPPVTPVVILSIIN-------------FFERLCLTWIFFFMMCVAERTYKQRFLFAKLFSHITSARKARKYEIPHFRLKKVENIKIWLSLRSYLKRRGPQRSVDVVVSSVFLLTLSIAFICCAQVLQGHKTFLNDAYNWEFLIWETALLLFLLRLASLGSETNKKYSNVSILLTEQINLYLKMEKKPNKKEQLTLVNNVLKLSTKLLKELDTPFRLYGLTMNPLIYNITRVVILSAVSGVISDLLGFNIRLWKIKS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QZ09-1", "uniprot_id": "PHTF1_MOUSE", "id": "Q9QZ09-1", "name": "Protein PHTF1", "aln": "MASNERDAISWYQKKIGAYDQQIWEKSIEQTQIKGFKNKPKKMGHIKPDLIDVDLIRGSTFAKAKPEIPWTSLTRKGLVRVVFFPLFSSWWIQVTSLRIFVWLLLLYLMQVTAVVLYLLMP-------------------------------------IVSASEVLGPLCLMLLMGTVHCQIVSTQITR-PSGNNGNRRRRKLRKTVNGD--GSRDNGNNSPDKVRAVETLESASSVGGFWGTLFGNRIKR----------------------------------VKLVSNKGTETDNDSGCFHPILKKRQGRPEIRMWQAREKAKVSDGEKCRREAYRR---------LGNGISDDLSSEEDGEARTQMILLRRSVEGASSDNGYEVKNRRSILSRHLNSQVKKT-TRWCHIVRDSDSLAESEFESAVFSQGSRSGMSGGSRSLN--LSRRDSESTRHDSETEDMLWDDLLHGPECRS------------SVTSDSEGAHVNTIHSGTKRDPKEDVFQQN-------HLFWLQNSSPASERVSAIIWEGNECKKMDMSVLEISGIIMSRVNAYEQGVGYQMLGNAVTVGLALFPFLYRLFREKS---FDQLKSISAEEVLTLFCGAPPVTPVVILSIIN-------------FIERLCLTWMFFFMMCVAERTYKQRFLFAKLFSHITSARKARKYEIPHFRLKKVENIKIWLSLRSYLKRRGPQRSVDVVVSSVFLLTLSIAFICCAQVLQGHKTFLNDAYNWEFLIWETALLLFLLRLASLGSETNKKYSNVSILLTEQINLYLKMEKKPNKKEQLTLVNNVLKLSTKLLKELDTPFRLYGLTMNPLIYNITRVVILSAVSGVISDLLGFNIRLWKIKS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UMS5-1", "uniprot_id": "PHTF1_HUMAN", "id": "Q9UMS5-1", "name": "Protein PHTF1", "aln": "MASNERDAISWYQKKIGAYDQQIWEKSIEQTQIKGLKNKPKKMGHIKPDLIDVDLIRGSTFAKAKPEIPWTSLTRKGLVRVVFFPLFSNWWIQVTSLRIFVWLLLLYFMQVIAIVLYLMMP-------------------------------------IVNISEVLGPLCLMLLMGTVHCQIVSTQITR-PSGNNGNRRRRKLRKTVNGD--GSRENGNNSSDKVRGIETLESVPIIGGFWETIFGNRIKR----------------------------------VKLISNKGTETDNDPSCVHPIIKRRQCRPEIRMWQTREKAKFSDGEKCRREAFRR---------LGNGVSDDLSSEEDGEARTQMILLRRSVEGASSDNGCEVKNRKSILSRHLNSQVKKTTTRWCHIVRDSDSLAESEFESAAFSQGSRSGVSGGSRSLN--MSRRDSESTRHDSETEDMLWDDLLHGPECRS------------SVTSDSEGAHVNTLHSGTKRDPKEDVFQQN-------HLFWLQNSSPSSDRVSAIIWEGNECKKMDMSVLEISGIIMSRVNAYQQGVGYQMLGNVVTIGLAFFPFLHRLFREKS---LDQLKSISAEEILTLFCGAPPVTPIIVLSIIN-------------FFERLCLTWMFFFMMCVAERTYKQRFLFAKLFSHITSARKARKYEIPHFRLKKVENIKIWLSLRSYLKRRGPQRSVDVVVSSVFLLTLSIAFICCAQVLQGHKTFLNDAYNWEFLIWETALLLFLLRLASLGSETNKKYSNVSILLTEQINLYLKMEKKPNKKEQLTLVNNVLKLSTKLLKELDTPFRLYGLTMNPLIYNITRVVILSAVSGVISDLLGFNIRLWKIKS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V9A8-1", "uniprot_id": "PHTF_DROME", "id": "Q9V9A8-1", "name": "Protein phtf", "aln": "--MKLDEIVAWYQKRIGTYDKQEWEKTVEQRILDGFNSVNLKNTKLKTELIDVDLVRGSTFPKAKPKQSLLTVIRLAILRYVLLPLYAQWWVKQTTPNAFGFILVLYLTQLTNWAIYVLHSSRIVPLDYEKPPNGTLLQAEADGDASDKDADKESEEHAALLSALLIPCALSLLISLIHSQIVATNTASGVSGGSSKNKLRRISASYLSDKAATRENRVRRRKKIVRVRQVEADLSQASSNISLPNRRTATSTIEVLPRPVTPLPSPTVTCATVPDPTTPTTPSPSVIRRSTNEETYLTTTAISPLTQPLAAIDACYDLSRKAGGAAPESPKKRNVNWHTPIQIYATYELGEEPCSSRKVAEESAPESVGERLCSVKPDYQTRRNIGEDDGFESLNGKSSSGEDNNHSPLPNAVAVAAPPAPVQTNQLRLRLNTTNGVTASASPTEKKPQSRGNESSTSCAESDECDDADIMSSPASGCNQECTTSATDWLGVTTNSEDCSYTSDLDHSDGGLKHTAFSDEDPGELDITPTTILNPHSSLDRISCTIWDQRDAKKAQLSVLEIASCIIERVDSMGEANDYIYIGVVFSFLLTLIPIFCRLCEVTLGSDAEKASEISYFNMPQLLWEKSSASLFTLLGLAFGDSQWERMVLALGFVQRLCLTLILFIIFAVAERTFKQRFLYAKLFSHLTSSRRARKSNLPHFRLNKVRNIKTWLSVRSYLKKRGPQRSVDIIVSAAFIVTLLLLAFLSVEWLK-DSAHLHTHLTLEALIWSITIGIFLLRFMTLGQKIQHKYRSVSVLITEQINLYLQIEQKPKKKDELMVSNSVLKLAADLLKELETPFKLSGLSANPYLFTTIKVVILSALSGVLSEVLGFKLKLHKIKIK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : ::****:**:**:* ***::** :.*::. * ::*.:******:*****.****: . :: * .::* *::**::.**:: *: . * ::*:**: *: .:*:: . . * :* * .* **:. :*.***:*: : **...:.: *:: : .* .:*:* . .*: :. ::: .. :: ..* : ... ** . .. *: : . : . .:. * *. :: **: ... . *:. ..: * . .: .. .: . *. : .* .:. : : * : . * : :. : .: .*::..: . : . *..**: :*::: *:: .* . . .**::**.. .: . :. . *. .*.:: : *. .: :*:*. **: .:.** ::*****:. *:.**:: :. .* :* ..:. *:::*:: ** . . :: ..** :: *: ...: . :*.: *.:***** ::*:::.*****:*****:******:**:*:*** ::*****:**.*** ***:*****:********::**:.*::** : : ..: *: ..:.*: . * ***. :: :****: :**.: ::** .**:*:********::*:**:**::* : *.****::.*****:***:* **: ** ::. :******:***:*::***:::* *** ", "identical_positions": 242, "similar_positions": 296, "identity": "27.41%" }, { "cls_id": "homologset.agr.MGI:1333110", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LN87-1", "uniprot_id": "F1LN87_RAT", "id": "F1LN87-1", "name": "MAP kinase-activated protein kinase 5", "aln": "MSEDSNMEKAIKETSILEEYSINWTQKLGAGISGPVRVCVKKSTQERFALKILLDRPKARNEVRLHMMCATHSNIVEIIEVFANSVQFPHESSPRARLLIVMEMMEGGELFHRISQHRHFTEKQASQVTKQATLALQHCHLLNIAHRDLKPENLLFKDNSLDAPVKLCDFGFAKVDQGDLMTPQFTPYYVAPQVLEAQRRHQKEKSGLIPTSPTPYTYNKSCDLWSLGVIIYVMLCGYPPFYSKHHSRTIPKDMRKKIMTGSFEFPEEEWSQISEMAKDVVRKLLKVKPEERLTIEGVLDHPWLNSTEALDNVLPSAQLMMDKAVVAGIQQAHAEQLANMRIQDLKVSLKPLHSVNNPILRKRKLLGSKPKDGVYIHDHENGVEDSNVALEKLRDVIAQCILPQAGKGENEDEKLNEVMQEAWKYNRECKLLRDALQSFSWNGRGFTDKVDRLKLAEVVKQVIEEQTLPHEPQSSEIALLVCRAGTWKRL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O54992-1", "uniprot_id": "MAPK5_MOUSE", "id": "O54992-1", "name": "MAP kinase-activated protein kinase 5", "aln": "MSEDSDMEKAIKETSILEEYSINWTQKLGAGISGPVRVCVKKSTQERFALKILLDRPKARNEVRLHMMCATHPNIVQIIEVFANSVQFPHESSPRARLLIVMEMMEGGELFHRISQHRHFTEKQASQVTKQIALALQHCHLLNIAHRDLKPENLLFKDNSLDAPVKLCDFGFAKVDQGDLMTPQFTPYYVAPQVLEAQRRHQKEKSGIIPTSPTPYTYNKSCDLWSLGVIIYVMLCGYPPFYSKHHSRTIPKDMRKKIMTGSFEFPEEEWSQISEMAKDVVRKLLKVKPEERLTIEGVLDHPWLNSTEALDNVLPSAQLMMDKAVVAGIQQAHAEQLANMRIQDLKVSLKPLHSVNNPILRKRKLLGTKPKDGIYIHDHENGTEDSNVALEKLRDVIAQCILPQAGKGENEDEKLNEVMQEAWKYNRECKLLRDALQSFSWNGRGFTDKVDRLKLAEVVKQVIEEQTLPHEPQ-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IW41-1", "uniprot_id": "MAPK5_HUMAN", "id": "Q8IW41-1", "name": "MAP kinase-activated protein kinase 5", "aln": "MSEESDMDKAIKETSILEEYSINWTQKLGAGISGPVRVCVKKSTQERFALKILLDRPKARNEVRLHMMCATHPNIVQIIEVFANSVQFPHESSPRARLLIVMEMMEGGELFHRISQHRHFTEKQASQVTKQIALALRHCHLLNIAHRDLKPENLLFKDNSLDAPVKLCDFGFAKIDQGDLMTPQFTPYYVAPQVLEAQRRHQKEKSGIIPTSPTPYTYNKSCDLWSLGVIIYVMLCGYPPFYSKHHSRTIPKDMRRKIMTGSFEFPEEEWSQISEMAKDVVRKLLKVKPEERLTIEGVLDHPWLNSTEALDNVLPSAQLMMDKAVVAGIQQAHAEQLANMRIQDLKVSLKPLHSVNNPILRKRKLLGTKPKDSVYIHDHENGAEDSNVALEKLRDVIAQCILPQAGKGENEDEKLNEVMQEAWKYNRECKLLRDTLQSFSWNGRGFTDKVDRLKLAEIVKQVIEEQTTSHESQ-----------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***:*:*:****************************************************************.***:****************************************************** :***:*************************************:********************************:***********************************************:***************************************************************************************************************:****.:********.***************************************************:**********************:********* .**.* ", "identical_positions": 453, "similar_positions": 18, "identity": "92.45%" }, { "cls_id": "homologset.agr.MGI:1333111", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P17708-1", "uniprot_id": "DCAM_RAT", "id": "P17708-1", "name": "S-adenosylmethionine decarboxylase proenzyme", "aln": "---------------------MEAAHFFEGTEKLLEVWFSRQQSDASQGSGDLRTIPRSEWDVLLKDVQCSIISVTKTDKQEAYVLSESSMFVSKRRFILKTCGTTLLLKALVPLLKLARDYSGFDSIQS---------FFYSRKNFMKPSHQGYPHRNFQEEIEFLNAIFPNGAAYCMGRMN-SDCWYLYTLDLP-----------ESRVINQPDQTLEILMSELDPAVMDQFYMKDGVTAKDVTRES-----------------------GIRDLIPGSVIDATLFNPCGYSMNGMKSDGTYWTIHITPEPEFSYVSFETNLSQTSYD-------DLIRKVVEVFKPGKFVTTLFVNQSSKCRTVLSSPQKIDG----FKRLDCQSAMFNDYNFVFTSFAKKQQQQS--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3Z6H8-1", "uniprot_id": "DCAM2_MOUSE", "id": "D3Z6H8-1", "name": "S-adenosylmethionine decarboxylase proenzyme 2", "aln": "---------------------MEAAHFFEGTEKLLEVWFSRQQSDASQGSGDLRTIPRSEWDVLLKDVQCSIISVTKTDKQEAYVLSESSMFVSKRRFILKTCGTTLLLKALVPLLKLARDYSGFDSIQS---------FFYSRKNFMKPSHQGYPHRNFQEEIEFLNAIFPNGAAYCMGRMN-SDCWYLYTLDFP-----------ESRVISQPDQTLEILMSELDPAVMDQFYMKDGVTAKDVTRES-----------------------GIRDLIPGSVIDATLFNPCGYSMNGMKSDGTYWTIHITPEPEFSYVSFETNLSQTSYD-------HLIRKVVEVFKPGKFVTTLFVNQSSKCRTVLSSPQKIDG----FKRLDCQSAMFNDYNFVFTSFAKKQQQQQS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P17707-1", "uniprot_id": "DCAM_HUMAN", "id": "P17707-1", "name": "S-adenosylmethionine decarboxylase proenzyme", "aln": "---------------------MEAAHFFEGTEKLLEVWFSRQQPDANQGSGDLRTIPRSEWDILLKDVQCSIISVTKTDKQEAYVLSESSMFVSKRRFILKTCGTTLLLKALVPLLKLARDYSGFDSIQS---------FFYSRKNFMKPSHQGYPHRNFQEEIEFLNAIFPNGAAYCMGRMN-SDCWYLYTLDFP-----------ESRVISQPDQTLEILMSELDPAVMDQFYMKDGVTAKDVTRES-----------------------GIRDLIPGSVIDATMFNPCGYSMNGMKSDGTYWTIHITPEPEFSYVSFETNLSQTSYD-------DLIRKVVEVFKPGKFVTTLFVNQSSKCRTVLASPQKIEG----FKRLDCQSAMFNDYNFVFTSFAKKQQQQQS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P91931-1", "uniprot_id": "DCAM_DROME", "id": "P91931-1", "name": "S-adenosylmethionine decarboxylase proenzyme", "aln": "-------------------MLENGSHFFEGVEKLLEIWFE----ESSNGDDDLRNISRSDWENVLSNVNCQIISTSKNDIIDAFVLSESSMFVSKRRWILKTCGTTTPLKCLGQLLKLAEAN-GYNVVAD---------LFYSRKNFTRPEAQITPHQGFTEEVTYLDSIFPNGRSYCLGSMN-LECWYLYTFSRSDIKITPQLISDEKNVDSDPDQTIEILMQDLDPETMSIFYKNKFNDANGATVKS-----------------------GIDTILPTMHIDDFLFDPCGYSMNGINDKGEYMTIHITPENQFSYVSFETNVALSNYR-------KLINQVINTFKPGKFIVTIFANKCSLAYETMKELEVEYSQGSHWKRTDMQCCNFPSYNLLFAQYSHSEKTGDNL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P21182-1", "uniprot_id": "DCAM_YEAST", "id": "P21182-1", "name": "S-adenosylmethionine decarboxylase proenzyme", "aln": "MTVTIKELTNHNYIDHELSATLDSTDAFEGPEKLLEIWFFP-HKKSITTEKTLRNIGMDRWIEILKLVKCEVLSMKKTKELDAFLLSESSLFVFDHKLTMKTCGTTTTLFCLEKLFQIVEQELSWAFRTTQGGKYKPFKVFYSRRCFLFPCKQAAIHQNWADEVDYLNKFFDNGKSYSVGRNDKSNHWNLYVTETDRSTPK------GKEYIEDDDETFEVLMTELDPECASKFVCGPEASTTALVEPNEDKGHNLGYQMTKNTRLDEIYVNSAQDSDLSFHHDAFAFTPCGYSSNMILAEKYYYTLHVTPEKGWSYASFESNIPVFDISQGKQDNLDVLLHILNVFQPREFSMTFFTKNYQ--NQSFQKLLSINESLPDYIKLDKIVYDLDDYHLFYMKLQKKI------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.:. *** *****:** .: . **.* . * :*. *:*.::* .*.. :*::*****:** .:: :****** * .* *:::.. .: .****: * * * *:.: :*: :*: :* ** :*.:* : : * **. . .. .: *:*:*:** :*** . * :. . . . * * ***** * : . * *:*:*** :**.***:*:. . .:: ::::.*:* :* *:*.:: . : . : : * : .*::.: . :. ", "identical_positions": 90, "similar_positions": 104, "identity": "21.9%" }, { "cls_id": "homologset.agr.MGI:1333112", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62826-1", "uniprot_id": "RAN_HUMAN", "id": "P62826-1", "name": "GTP-binding nuclear protein Ran", "aln": "---MAAQGEPQVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCGNKVDIKDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPNLEFVAMPALAPPEVVMDPALAAQYEHDLEVAQTTALPDEDD-DL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62828-1", "uniprot_id": "RAN_RAT", "id": "P62828-1", "name": "GTP-binding nuclear protein Ran", "aln": "---MAAQGEPQVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCGNKVDIKDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPNLEFVAMPALAPPEVVMDPALAAQYEHDLEVAQTTALPDEDD-DL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P62827-1", "uniprot_id": "RAN_MOUSE", "id": "P62827-1", "name": "GTP-binding nuclear protein Ran", "aln": "---MAAQGEPQVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCGNKVDIKDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPNLEFVAMPALAPPEVVMDPALAAQYEHDLEVAQTTALPDEDD-DL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P79735-1", "uniprot_id": "RAN_DANRE", "id": "P79735-1", "name": "GTP-binding nuclear protein Ran", "aln": "----MAENEPQVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGAIKYNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCGNKVDIKDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPNLEFVEMPALAPPEIAMDPTLAAQYEHDLKVASETALPDEDD-DL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VZ23-1", "uniprot_id": "RAN_DROME", "id": "Q9VZ23-1", "name": "GTP-binding nuclear protein Ran", "aln": "---MAQEGQDIPTFKCVLVGDGGTGKTTFVKRHMTGEFEKKYVATLGVEVHPLIFHTNRGAIRFNVWDTAGQEKFGGLRDGYYIQGQCAVIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCGNKVDIKDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLVGDPNLEFVAMPALLPPEVKMDKDWQAQIERDLQEAQATALPDEDE-EL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32836-1", "uniprot_id": "GSP2_YEAST", "id": "P32836-1", "name": "GTP-binding nuclear protein GSP2/CNR2", "aln": "MSAPAQNNAEVPTFKLVLVGDGGTGKTTFVKRHLTGEFEKKYIATIGVEVHPLSFYTNFGEIKFDVWDTAGQEKFGGLRDGYYINAQCAIIMFDVTSRITYKNVPNWHRDLVRVCENIPIVLCGNKVDVKERKVKAKTITFHRKKNLQYYDISAKSNYNFEKPFLWLARKLAGNPQLEFVASPALAPPEVQVDEQLMHQYQQEMDQATALPLPDEDDADL", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P32835-1", "uniprot_id": "GSP1_YEAST", "id": "P32835-1", "name": "GTP-binding nuclear protein GSP1/CNR1", "aln": "MSAPAAN-GEVPTFKLVLVGDGGTGKTTFVKRHLTGEFEKKYIATIGVEVHPLSFYTNFGEIKFDVWDTAGQEKFGGLRDGYYINAQCAIIMFDVTSRITYKNVPNWHRDLVRVCENIPIVLCGNKVDVKERKVKAKTITFHRKKNLQYYDISAKSNYNFEKPFLWLARKLAGNPQLEFVASPALAPPEVQVDEQLMQQYQQEMEQATALPLPDEDDADL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ** *****************:********:**:******* *:** * *:::*******************:.***:********:*****************************:*:******:*.******************************* *:*:**** *** ***: :* * ::::. * .*****: :*", "identical_positions": 160, "similar_positions": 28, "identity": "72.73%" }, { "cls_id": "homologset.agr.MGI:1333114", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q642B8-1", "uniprot_id": "Q642B8_RAT", "id": "Q642B8-1", "name": "", "aln": "MVLKAFFPTCCASADSGLLVGRWVPGQNSAVILAVVHFPFIPIQVKELLAQVQKASQVQVTVLG-----TWCHRQQEPEESLGKFLEG-LGAIFSHNPWLQLCREKGTRFWSCKATYH--------QMSSTLDTPTEDQVMLIFYDQRKLLLSWLHPPPVLPDCQIGDSTASTGGLADIFDTVARSEVLFRNDQFDEGPVRLSHWQSEGVEASILVELAKRASGPVCLLLASLLSLISAASACRLWKLGPLAFIRSKLSTCEQLQHRLKHLSFIFSTEKAQSPMQLMRKANMLVSVLLDVALGLLLLSWLHSNNRIGQLANALVPVADRVAEELQHLLQWLMGAPAGLKMNRALDQVLGRFFLYHIHL----WISYIHLMSPFIEHILWHVGLSACLGLTVALSIFSDIIALLTFHIYCFYVYGARLYCLKIYGLSSLWRLFRGKKWNVLRQRVDSCSYDLDQLFIGTLLFTILVFLLPTTALYYLVFTLLRLLVITVQGLIHLLVDLINSLPLYSLGLRLCRPYRLAAG---VKFR-------------------------------VLEKEAGRP--LRLLMQINP---------------LPYSHVVHTYRLPSCGCHPKHSWGTLCRKLFFGELIYPWRQREDKQD--------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QYT7-1", "uniprot_id": "PIGQ_MOUSE", "id": "Q9QYT7-1", "name": "Phosphatidylinositol N-acetylglucosaminyltransferase subunit Q", "aln": "MVLKVFFPTCCASADSGLLVGRWVPGQSSAVILAVVHFPFIPIQVKELLAQVQKASQVPVAVLG-----TWCHRQQEPQESLGNFLEG-LGTIFSHDPWLQLCRERGTRLWSCKATYP--------QMSNPLDMHPEEQVMLIFYDQRKLLLSWLHPPPVLPACQMGDTTASTGGLADIFDTVARSEVLFRNDQFDERPVRLSHWQSEGVEASILVELAKRASGPVCLLLASLLSLISAASACRLWKLWPLSFIRSKLSTCEQLHHRLKHLSFIFSTEKAQNPMQLMRKANMLVSVLLDVALGLLLLSWLHSNNRIGQLANALVPVADRVAEELQHLLQWLMGAPAGLKMNRALDQVLGRFFLYHIHL----WISYIHLMSPFIEHILWHVGLSACLGLTVALSIFSDIIALLTFHIYCFYVYGARLYCLKIYGLSSLWRLFRGKKWNVLRQRVDSCSYDLDQLFIGTLLFTILVFLLPTTALYYLVFTLLRLLVITVQGLIHLLVDLINSLPLYSLGLRLCRPYRLAAG---VKFR-------------------------------VLEKEAGRP--LRLLMQINP---------------LSYNHVMHIYRLPRCGCHPKHSWGTLCRKLVFGELIYPWRQREDKQD--------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BRB3-1", "uniprot_id": "PIGQ_HUMAN", "id": "Q9BRB3-1", "name": "Phosphatidylinositol N-acetylglucosaminyltransferase subunit Q", "aln": "MVLKAFFPTCCVSTDSGLLVGRWVPEQSSAVVLAVLHFPFIPIQVKQLLAQVRQASQVGVAVLG-----TWCHCRQEPEESLGRFLES-LGAVFPHEPWLRLCRERGGTFWSCEATHR--------QAPTAPGAPGEDQVMLIFYDQRQVLLSQLHLPTVLPDRQAGATTASTGGLAAVFDTVARSEVLFRSDRFDEGPVRLSHWQSEGVEASILAELARRASGPICLLLASLLSLVSAVSACRVFKLWPLSFLGSKLSTCEQLRHRLEHLTLIFSTRKAENPAQLMRKANTVASVLLDVALGLMLLSWLHGRSRIGHLADALVPVADHVAEELQHLLQWLMGAPAGLKMNRALDQVLGRFFLYHIHL----WISYIHLMSPFVEHILWHVGLSACLGLTVALSLLSDIIALLTFHIYCFYVYGARLYCLKIHGLSSLWRLFRGKKWNVLRQRVDSCSYDLDQLFIGTLLFTILLFLLPTTALYYLVFTLLRLLVVAVQGLIHLLVDLINSLPLYSLGLRLCRPYRLADKPTALQPRGAHLPPPQLWLPPQALLGRPVPQAVPWGAHLPLEAERGQAGLRELLARLAPPHGHSQPSALPGWHQLSWRMSCALWTLLCAPEHGRPCYHTLGLEVIGSEQMWGWPARLAALHHWHCLPWDPLPTCCGHHGGEHSNPRCPEHCPMPTLCTQVQRVRPPQQPQVEGWSPWGLPSGSALAVGVEGPCQDEPPSPRHPLAPSAEQHPASGGLKQSLTPVPSGPGPSLPEPHGVYLRMFPGEVAL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QHT3-1", "uniprot_id": "F1QHT3_DANRE", "id": "F1QHT3-1", "name": "", "aln": "MVLKIFFPQCCNTADSGLLVGRWIPGHNSAVVLAVVHYPFIPGQVKKYLSEIQSQTQVDLAVLG-----SWSMPK-EGQEGLDSFLKD-LSTIFPQKCWLQLSREIGKRGFTCRVVQNNGMLLQDKEQKSDVDGSEEDKIILVHYDQRKVMLSQLHP--VQEADQKSEIEPSE--LRLVFQTVAQSQPLFFLDKYDDGPLKLTHWQSEGREASIIAELLKQASVPVCICLTWLLSLWLWFCSFRILNIPPVKFITSKLSTCVQSGYRAVHFKTVFSPKKADTHMDFMRKANIFVSFLVDIAFGLLLISWLYRENRISKLANTLVPVADHVAKELQQLLEWLMGAPAGLKMNKALDQVLGRFFLYHIHL----WISYIHLMSPFIERILWYVGLSACLGLTFALSILSDIVALLTFHIYCFYVYGARLYCLKIYGLSSLWRLFRGKKWNVLRQRVDSCSYDLDQLFIGTLLFTILLFLLPTTALYYLVFTLLRLVVVLFQGVIHLSVDFINSFPLFAIGLRICRPYRLAEG---VKFK-------------------------------VLCEESGSP--LHLMMEINP---------------LKCSSVLQRYRTPTYSCYPKDSWAALCKKLFVGELIYPWKQKTDKTD--------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P53306-1", "uniprot_id": "GPI1_YEAST", "id": "P53306-1", "name": "Phosphatidylinositol N-acetylglucosaminyltransferase subunit GPI1", "aln": "MPNYIFWPYESLFENSAAQG----PQVALAISFEKTHFVVLGVCEPQYLEEVSIRPPYSVVATKNNGAEGWNYKVADPCNVHFRIPKLKFMQFYSSDPISLIIPEKEVGLHSSVGETLN-----YSKLEQHPRYKRDNKKLSETLNIINLFPAYCKALNELYPFIQTSQENLRGTMLNSVAAWCSSTCIYKMVAKIGFYLTFVICSIASLVSSLLNYSHFQLVN--YSAFVQQIDLRCQQICYFPVQYERINKKDNIQNVGSMVEKDNSNSQFSHSYMPSKFYPDYILLYNTIWLIINDISFGLILGAILIE-NRDFLVSASHRVLKFFLYDSLKTITETLANNPLGIKLNAELANFLSELFLWVIEFSYTTFIKRLIDPKTLSSLLTLTIYMMFLVGFSFAVSLAIDFFAILSFPIYVFYRISSKLYHCQLNIMASLFNLFCGKKRNVLRNRIDHNYFQLDQLLLGTLLFIILVFLTPTVMAFYMSYTVLRMLTITIEIFSEAVIALINHFPLFALLLRLKDPKRLPGG------------------------------------ISIELKTTVSNKHTTLELQNNP---------------IKFKSMFRPYNLLLSQMRTNYFSFATVRKIVRGESIMVNRNKLYYVLYSSLPSKPLSVKDLYKRLTIQA----------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q8IR17-1", "uniprot_id": "Q8IR17_DROME", "id": "Q8IR17-1", "name": "", "aln": "MSIKIYLPVNYYYLNKSTNLY----GQVQINEDNVVSYYVLEASDLEFSDKAINHEKGNLRFLG-------SILNEDFNADQNQFLKFNMRLCFTYN-------------------------------------SSQANITLVYLGITPEYLKHIKVILYDKQMVRN----------------------LFVSGESENRRSLEYNDNDSTDCDFLELSRLNQPTADNQNKANNNANKSIQYGLTLIADSPIKIFEYMAENVFINSIMVHTTIYKHFKEWQTACDKRSRPANIVLDRILGIILMLILFTLATQ------PGDFLIQISHYVIDELYGLLKVLEGSPIGLKLNIHLNNFFLDCFKYHIEL----WSTFLDFIEPLVRQVFLAIGMIGCLGFTFQIALLVDLISVIGLHSHCFYIYTKVLYNVERRGLSVLWQVVRGNRYNILKGRTESHNYMNRQLYLATIFFSAILFLLPTTLVYYIVFAALKALTFATLSVFHFLRRKLMYLPIEVCIKRLLRGCHEIDC---------------------------------------IQIKDVSHHERAFLMHKQQ------------------KINVTVYKITTL----------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : * :.. : .: : : : : : : : :. . : : . : : . . ..:: . . : . . . * . : .: : *:* : . : : ..* : : * . * *:*:* * :.: * : *.: : . : ..: : : : :*::. ::: *:.::: : : ** ** : :: *:.:. *:: *:*: * : : ** :.*::* ::** **. :*: :: *: :.. . . : :*: *: : : . : ", "identical_positions": 37, "similar_positions": 118, "identity": "4.76%" }, { "cls_id": "homologset.agr.MGI:1333115", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0M212-1", "uniprot_id": "A0ABK0M212_RAT", "id": "A0ABK0M212-1", "name": "2'-phosphotransferase", "aln": "MDWVLVMNAPGGRRQE-----GRRTHRPREQDRNVQLSKALSYALRHGALKLGLPMRADGFVPLQALLQLPQFHS--FSIEDVQLVVDTNEKQRFTLQPGEPSTGPLIRANQGHSLQVPELELMPLETP---QALPSTLVHGTFWKHWPSILLN-GLSRQGRTHIHLASGLPGDSGVISGIRPNCEVAVFINGALALTDG-IPFFCSVNGVILTPGNADGFLLPKYFKEALQLRPTRKPLSLTGDKETESQSGPKHSSRGGRRKIQ-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K3A2-1", "uniprot_id": "TRPT1_MOUSE", "id": "Q8K3A2-1", "name": "tRNA 2'-phosphotransferase 1", "aln": "------MNAPGGRRKE-----GRRTHRPREQDRNVQLSKALSYALRHGALKLGLPMRADGFVPLQALLQLPQFHS--FSIEDVQLVVNTNEKQRFTLQPGEPSTGLLIRANQGHSLQVPELELTPLETP---QALPLTLVHGTFWKHWPSILLK-GLSRQGRTHIHLASGLPGDPGVISGIRPNCEVAVFIDGPLALTDG-IPFFCSANGVILTPGNAEGFLLPKYFKEALQLRPTRKPLSLAGDKETETQSGPKLSSRGGRRKIQQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86TN4-1", "uniprot_id": "TRPT1_HUMAN", "id": "Q86TN4-1", "name": "tRNA 2'-phosphotransferase 1", "aln": "------MNFSGGGRQEAAGSRGRRAPRPREQDRDVQLSKALSYALRHGALKLGLPMGADGFVPLGTLLQLPQFRG--FSAEDVQRVVDTNRKQRFALQLGDPSTGLLIRANQGHSLQVPKLELMPLETP---QALPPMLVHGTFWKHWPSILLK-GLSCQGRTHIHLAPGLPGDPGIISGMRSHCEIAVFIDGPLALADG-IPFFRSANGVILTPGNTDGFLLPKYFKEALQLRPTRKPLSLAGDEETECQSSPKHSSRE-RRRIQQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5EAR5-1", "uniprot_id": "TRPT1_DANRE", "id": "Q5EAR5-1", "name": "tRNA 2'-phosphotransferase 1", "aln": "------MDCETRGRGR-----RGRGNR-NEESRDVRLSKSLSYVLRHGASKMGLQMNSDGFVFVEELLAHQQFRS--FSVDDVERVVASNDKQRFKLCKHPEDDRLQIRANQGHSVQVTDLELREISQDD--QDYPREAVHGSYMKHWPSIRSQ-GLSRMNRTHIHLAPGLPGEGRVISGMRQSCDLAVYIDVTKAMSDG-IKFFWSENGVLLTPGDAAGILAPCYFSRAQRLKP------LPCDIELH------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q86BH3-1", "uniprot_id": "Q86BH3_DROME", "id": "Q86BH3-1", "name": "2'-phosphotransferase", "aln": "------MAS--------------------NQQINTQLSKKLSWLLRHGAKTEGITIRADGFVSVPDLQKHPRYLC--FTLEKLKEIAAADAKQRYTLRWNPELGVHEIRANQGHSLAVLEGEAGGLENITH-VSQVPLAVHGTYYRHWGAIRSQ-GLSRMNRNHVHFACSDETNS-TLSGFRSDCQILIYLNVEKVLADG-IPIYRSSNNVLLCPG-IEGFIHSSYFQRVVDKKTG-----QPLQIDHCY-----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12272-1", "uniprot_id": "TPT1_YEAST", "id": "Q12272-1", "name": "tRNA 2'-phosphotransferase", "aln": "-----------------------MRQVLQKDKRDVQLSKALSYLLRHTAVKEKLTIDSNGYTPLKELLSHNRLKTHKCTVDDIHRIVKENDKQRFHIKTLG-ADEEWICATQGHSIKSIQPSDEVLVPITEASQLPQELIHGTNLQSVIKIIESGAISPMSRNHVHLSPGMLHAKGVISGMRSSSNVYIFIDCHSPLFFQTLKMFRSLNNVYLSSSIPVELIQKVVVKGNLKDEEKLDTLRRILHERNIPLEKI-------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::. :.:*** **: *** * . : : ::*:. : * : : :.:. :. : ***: : * *.****: . . : :**: : * . .:* .*.*:*:: . :**:* .:: :::: : : :: * *.* * .. :: .. . . ", "identical_positions": 34, "similar_positions": 65, "identity": "12.73%" }, { "cls_id": "homologset.agr.MGI:1333743", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A1L314-1", "uniprot_id": "MPEG1_MOUSE", "id": "A1L314-1", "name": "Macrophage-expressed gene 1 protein", "aln": "MNS-FMALVLIWMIIACAEADKPLGETGTTGFQICKNALKLPVLEVLPGGGWDNLRNVDMGRVMDLTYTNCKTTEDGQYIIPDEVYTIPQKESNLEMNSEVLESWMNYQSTTSLSINTELALFSRVNGKFSTEFQRMKTLQVKDQAVTTRVQVRNRIYTVKTTPTSELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDYISQTSLTKDYLSNRTNSRVQSFGGVPFYPGITLETWQKGITNHLVAIDRAGLPLHFFIKPDKLPGLPGPLVKKLSKTVETAVRHYYTFNTHPGCTNVDSPNFNFQANMDDDSCDAKVTNFTFGGVYQECTELSGD---VLCQNLEQKNLLTGDFSCPPGYSPVHLLSQTHEEGYSRLECKKKCT------LKIFCKTVCEDVFRVAKAEFRAYWCVAAGQVPDNSGLLFGGVFTDKTINPMTNAQSCPAGYIPLNLFES-LKVCVSLDYELGFKFSVPFGGFFSCIMGNPLVNSDTAKDVRAPSLKKCPGGFSQHLAVISDGCQVSYCVKAGIFTGGSLLPVRLPPYTKPPLMSQVATNTVIVTNSETARSWIKDPQTNQWKLGEPLELRRAMTVIHGDSNGMSGGEAAGITLGVTIALGIVITLAIYGTRKYKK-------KEYQEIEEQESLVGSLATDATVLNGEEDPSPA-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9WV57-1", "uniprot_id": "MPEG1_RAT", "id": "Q9WV57-1", "name": "Macrophage-expressed gene 1 protein", "aln": "MNS-FMAIALIWMMIACAEADKPLRDPGMTGFQTCKDTLKLPVLEVLPGGGWDNLRNIDMGRVIDLTYTNCKTTEDGQYIIPDEVYTIPQKESNLEMNSEIRDSWVNYQSTTSFSINTELSLFSKVNGKFSTEFQRMKTLQVKDQAVTTRVQVRNRIYTVKNSPTSELSFGFTNALMDICDQLEKNQTKMATYLAELLVLNYGTHVITSVDAGAALVQEDHIRSSFLLDNQNSENTVTASAGIAFLNIVNFKVETDHTSQTLLTKSYLSNRTNSRVQSFGGIPFYPGITLETWQKGITNHLVAIDRAGLPLHFFIKPDKLPGLPGGLVKKLSKTVETAVRHYYTFNTHPGCTNVDSPNFNFQANMEDDSCDAKVTNFTFGGLYQECTELSGD---ALCQNLEQKNLLTGDFSCPSGYTPVHLLSQTHEEGYSRLECKKKCT------LKIFCKTVCEDVFRVAKAQFRAYWCVATGQVPDNSGLLFGGLFTDKSINPMTNAQSCPAGYIPLNLFES-LKVCVSLDYELGYKFSVPFGGFFSCIMGNPLVNSDTAKDIGAPSLKKCPGGFSQHLAVISDGCQVSYCVKAGIFTGGSLLPVRLPPYTKPPLMSQVATNTVIVTSSETARSWIKDPQTNQWKLGEPLELHKAMTVIHGDGNGMSGGEAAGVTLGVIIALGIVITLAIYSTRKYKKE------KEYQEIEEQESLVGSFATDASPPNGEQDPCPA-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q2M385-1", "uniprot_id": "MPEG1_HUMAN", "id": "Q2M385-1", "name": "Macrophage-expressed gene 1 protein", "aln": "MNN-FRATILFWAAAAWAKSGKPSGEMDEVGVQKCKNALKLPVLEVLPGGGWDNLRNVDMGRVMELTYSNCRTTEDGQYIIPDEIFTIPQKQSNLEMNSEILESWANYQSSTSYSINTELSLFSKVNGKFSTEFQRMKTLQVKDQAITTRVQVRNLVYTVKINPTLELSSGFRKELLDISDRLENNQTRMATYLAELLVLNYGTHVTTSVDAGAALIQEDHLRASFLQDSQSSRSAVTASAGLAFQNTVNFKFEENYTSQNVLTKSYLSNRTNSRVQSIGGVPFYPGITLQAWQQGITNHLVAIDRSGLPLHFFINPNMLPDLPGPLVKKVSKTVETAVKRYYTFNTYPGCTDLNSPNFNFQANTDDGSCEGKMTNFSFGGVYQECTQLSGNRDVLLCQKLEQKNPLTGDFSCPSGYSPVHLLSQIHEEGYNHLECHRKCT------LLVFCKTVCEDVFQVAKAEFRAFWCVASSQVPENSGLLFGGLFSSKSINPMTNAQSCPAGYFPLRLFEN-LKVCVSQDYELGSRFAVPFGGFFSCTVGNPLVDPAISRDLGAPSLKKCPGGFSQHPALISDGCQVSYCVKSGLFTGGSLPPARLPPFTRPPLMSQAATNTVIVTNSENARSWIKDSQTHQWRLGEPIELRRAMNVIHGDGGGLSGGAAAGVTVGVTTILAVVITLAIYGTRKFKK-------KAYQAIEERQSLVPGTAATGDTTYQEQGQSPA-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0R063-1", "uniprot_id": "B0R063_DANRE", "id": "B0R063-1", "name": "Macrophage-expressed gene 1 protein", "aln": "MESRAFILLMLCCCMNFCNLSPLIRP--SNGLNECHKNSNLVALEVLPGGGWDNLRNIDMGRVMNLSYSQCQTTEDGVYLIPDEVFVIPQKENTVETNSEMIMSWLDQKSSTSSSINADVSFFSWLNGKFSREHQRIKTHQVKESSVTSRVQVRNRLYTVKAYPNFPLDSRFAQQVEEIADAITNDQTRLATYLSEKLILDYGTHVITSVEAGASLVQEDYLKMSYILKNQLDLSSVSASAGFNFFDKVKLDPSYNGGQKTSLNSSYQGNITYSLIQSHGGALFYPGMTLQKWQESTLNNLVAIDRSGLPLHYFLNPSTFPDISEALVRKLALSVSQAAEQYYKVNTIPGCVNVDSKNFNFQANVDDVSCEGPITNLSFGGMYQQCTPLTIDGS-TICDEMAQKNPATGGYSCSQKYNTTLLRSEIIERGYTRYECQDNCRSCGFLGWSTCCSQTCNNVNYIRRAKVDTLWCYSTQKIPEYSGYIFGGLYGPSMQNPFTRSYTCPPNFFVQPILSRAIMVCLSNDYVKATKSAVPFGGFFSCQSGNPLSN----------GESRCPPQFSQHLAAISDGCQVLYCVQSGVFSGGQLKPVLLPPYTSPPLVGMTVTNSVVVMT-DLNGSLVGVGQSRMWQPANPVEINQMFVR--------SGGKNAGVTYGLILLIALLVSGSVVFTT--------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A9C3Q1-1", "uniprot_id": "A9C3Q1_DANRE", "id": "A9C3Q1-1", "name": "Macrophage-expressed gene 1 protein", "aln": "MN---LLYIFLTFFVLFCKSDGFIRP--SNGLRECRQNSNLTALEVLPGGGWDNLRNLDVGRVMNLTYSQCQTTEDGLYLIPDEVFVIPRKTSGVETHSETIMSWLDQRSSTSGSINADASYLTVLNGKFSEENTRMKIHQVRGNSVTTRVQVRNHLYTVNAYPDFTLDSRFSQQISELADAIENNQTRQAMYLSEKVILEYGTHVITSIDAGATLVQEDYIKRSYVSDTNSERSSVSASAGINFFNMVNFNFGSKETEQTSETLTYQQNITYSLVQSHGGALFYQGITMQKWQESTQNHLVAIDRSGLPIHYFLNPAVFPDLPVPTLHKLAFSVQKAAERYYNINTTPGCTDQSSQNFNFQANVNDTSCEGPVTNLTFGGVYQTCTPESPDGN-VICDEFAQRNPDTGDFTCRQPYSATRLHSENVQQGYNNYECHEECHSCWLI--LDCCHQVCGNVYYVRQAQIDTYWCSTSQTVPENTGYLFGGLFGPSLQNPQTKSHDCPANYFEQVFLTNGMRICLSNDYEAGTISSVPFGGLFSCQSGNPQAG----------NQYRCPPQYSQHLATISDGCQVLYCVQSGVFTGGQLKPVHLPPFTKPPLINMMATNTVAVMT-EGDKAWMRVGGTKKWRVANLGEVSRMAKLIDASSTQMSGGEKAGVACGVMTLVAIVVAGIVILMKRRRKFSHFSFKRGYEEIQHDGQSTVEIEREQQNTNENPTQPLLP", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: :: .: . *.. *:. :* .**************:*:***::*:*::*:***** *:****::.**:* . :* :** ** : :*:** ***:: : :: :***** * *:* **: .::*:****** :***: * *. * : : ::.* : ::**: * **:* ::*:***** **::***:*:***::: *:: ..: . .:*:****: * : *::. . .:. . * * * * :** ** ** *:*:: **:. *:******:***:*:*::* :*.:. ::*:: :*. *..:**..** ***.: .* ******* :* **:. :**::***:** ** : : :*::: *:* **.::* *... * *: :.**.. **: :* * .* :* : :*:. : ** :: :*: :* :***:: . ** *.: **..:: :: : :*:* ** . :*****:*** *** . . :** :*** * ******* ***::*:*:**.* *. ***:* ***:. .**:* * . : : : :. *: .: *: : *** **:: *: :.:::: : ", "identical_positions": 246, "similar_positions": 208, "identity": "33.61%" }, { "cls_id": "homologset.agr.MGI:1333744", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0M4I1-1", "uniprot_id": "A0ABK0M4I1_RAT", "id": "A0ABK0M4I1-1", "name": "Platelet glycoprotein Ib alpha chain", "aln": "MGGIPSNSLCPQVHMALLILLFLLPSPLHSQPTCDVSKVTSLLEVNCEDKKLKKLPTDLPADTGILHLSKNQLGTFSTSYLVHFTHLTHLYLSRCELTSLQAHEKLLKLETLDLSHNHLQSLPSLGRALPALTTLDVSFNKLGSLSPGALEGLGQLEELYLQNNDLKSLPPGLLMPTTKLLKLSLANNKLRELPPGLLDGLEDLDTLYLQGNWLSTIPKGFFGSLLLPFVFLHANTWYCDCEILYFRNWLQENPNRVYLWKEGVDVKAMTANVASVRCANLGNAPVYSYPGKGCPTN--EGDIDYDDYADT--------PTTRTEVKFSTNTKAHTTYWGLFYSESSTSPDSQMTS-LPPIHEPTKKQPTFAHTEIPGFTTLPDTMESNTAFYSLN-NTVPTTTP---EPTSTQATPEPSSTPMLTTP-VPTPEPSSIPMLTVPVS-TPEPSSTPMLTTPVS-TPEPSSIPMPTIP-VPTPEPSSIPMPTIP-VPTPEPSSTPMPTIP-VPTPEPSSTPMFTTP-VPTPEPSSTPMLTTPTLTTPESSSTPSILVSTIPPVLTTTLAPPESIP-KTVLEQFYTLEPTLPRTLES-TIIIPEQNS-LNSQAVPQASSDTPKSNPFLNSDFCCLLPLGFYVLGLLWLLFASVVLIVLLTWIWHVTPHNLDMDQSAALATSTHTTSLEMQRARQVTMPWAWLLSLQGSLPTFRSSLFLWVRPNGRVGPLVAGRRPSALSQGHGQDLLGRVGIRYSGHSL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35930-1", "uniprot_id": "GP1BA_MOUSE", "id": "O35930-1", "name": "Platelet glycoprotein Ib alpha chain", "aln": "--------------MALLILLFLLPSPLHSQHTCSISKVTSLLEVNCENKKLTALPADLPADTGILHLGENQLGTFSTASLVHFTHLTYLYLDRCELTSLQTNGKLIKLENLDLSHNNLKSLPSLGWALPALTTLDVSFNKLGSLSPGVLDGLSQLQELYLQNNDLKSLPPGLLLPTTKLKKLNLANNKLRELPSGLLDGLEDLDTLYLQRNWLRTIPKGFFGTLLLPFVFLHANSWYCDCEILYFRHWLQENANNVYLWKQGVDVKDTTPNVASVRCANLDNAPVYSYPGKGCPTS--SGDTDYDDYDDIPDV-----PATRTEVKFSTNTKVHTTHWSLLAAAPSTSQDSQMIS-LPPTHKPTKKQSTFIHTQSPGFTTLPETMESNPTFYSLKLNTVLIPSPTTLEPTSTQATPEPNIQPMLTTSTLTTPEHSTTPVPTTTILTTPEHSTIPVPTTAILTTPKPSTIPVPTTATLTTLEPSTTPVPTTATLTTPEPSTTLVPTTATLTTPEHSTTPVPTTATLTTPEHSTTPVPTTATLTTPEPSTTLTNLVSTISPVLTTTLTTPESTPIETILEQFFTTELTLLPTLESTTTIIPEQNSFLNLPEVALVSSDTSESSPFLNSDFCCFLPLGFYVLGLLWLLFASVVLILLLTWTWHVTPHSLDMEQSAALATSTHTTSLEVQRARQVTMPRAWLLFLQGSLPTFRSSLFLWVRPNGRVGPLVAGRRPSALSQGRGQDLLGTVGIRYSGHSL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P07359-1", "uniprot_id": "GP1BA_HUMAN", "id": "P07359-1", "name": "Platelet glycoprotein Ib alpha chain", "aln": "--------------MPLLLLLLLLPSPLHPHPICEVSKVASHLEVNCDKRNLTALPPDLPKDTTILHLSENLLYTFSLATLMPYTRLTQLNLDRCELTKLQVDGTLPVLGTLDLSHNQLQSLPLLGQTLPALTVLDVSFNRLTSLPLGALRGLGELQELYLKGNELKTLPPGLLTPTPKLEKLSLANNNLTELPAGLLNGLENLDTLLLQENSLYTIPKGFFGSHLLPFAFLHGNPWLCNCEILYFRRWLQDNAENVYVWKQGVDVKAMTSNVASVQCDNSDKFPVYKYPGKGCPTLGDEGDTDLYDYYPEEDTEGDKVRATRTVVKFPT--KAHTTPWGLFYSWSTASLDSQMPSSLHPTQESTKEQTTFPPRWTPNFTLH---MESITFSKTPKSTTEPTPSP-----TTSEPVPEPAPN-------MTTLEP------------------TPSP---------------------TTPEPTSEPAPSPT---TPEPTSEPAPSPT---TPEPTSEPAPSPT---TPEP--TPIPTIATSPTILVSATS--LITPKSTFLTTTKP---------------------VSLLESTKKTIPELDQPPKLRGVLQGHLESSRNDPFLHPDFCCLLPLGFYVLGLFWLLFASVVLILLLSWVGHVKPQALDSGQGAALTTATQTTHLELQRGRQVTVPRAWLLFLRGSLPTFRSSLFLWVRPNGRVGPLVAGRRPSALSQGRGQDLLSTVSIRYSGHSL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.**:**:*******.: *.:***:* *****:.::*. **.*** ** ****.:* * *** : *: :*:** * *.*****.**.. .* * .******:*:*** ** :*****.******:* **. *.* **.:*:****:.*:**:****** **.** **.****:* ***.***:***:**** ** * * ********: ****.***.*.* *:*******.***:*.:.**:**:***** *.*****:* * .: ***.******** .** * ** :*** ***.* *.*** *.*: : .::* **** * * * ::.**:*.** *.** *** . : : .* .:* *:::..*** :.* * * .* **:: * *: . ****:: *: . *** :: * :.. *** **: * .* .* *:* *::. ...**** . *** . *** :. : * ::....***:.****:**********:**********:**:* **.*: ** *.***:*:*:** **:**.****:* **** *:***********************************:*****. *.********", "identical_positions": 371, "similar_positions": 146, "identity": "49.07%" }, { "cls_id": "homologset.agr.MGI:1333745", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P60192-1", "uniprot_id": "SNAPN_RAT", "id": "P60192-1", "name": "SNARE-associated protein Snapin", "aln": "-MAAAGSAAVSGAGTPVAGPTGRDLFAEGLLEFLRPAVQQLDSHVHAVRESQVELREQIDNLATELCRINEDQKVALDLDPYVKKLLNARRRVVLVNNILQNAQERLRRLNHSVAKETARRRAMLDS-GVYPPGSPSK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z266-1", "uniprot_id": "SNAPN_MOUSE", "id": "Q9Z266-1", "name": "SNARE-associated protein Snapin", "aln": "-MAAAGSAAVSGAGTPVAGPTGRDLFAEGLLEFLRPAVQQLDSHVHAVRESQVELREQIDNLATELCRINEDQKVALDLDPYVKKLLNARRRVVLVNNILQNAQERLRRLNHSVAKETARRRAMLDS-GVYPPGSPSK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95295-1", "uniprot_id": "SNAPN_HUMAN", "id": "O95295-1", "name": "SNARE-associated protein Snapin", "aln": "-MAGAGSAAVSGAGTPVAGPTGRDLFAEGLLEFLRPAVQQLDSHVHAVRESQVELREQIDNLATELCRINEDQKVALDLDPYVKKLLNARRRVVLVNNILQNAQERLRRLNHSVAKETARRRAMLDS-GIYPPGSPGK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1L8R9-1", "uniprot_id": "SNAPN_DANRE", "id": "Q1L8R9-1", "name": "SNARE-associated protein Snapin", "aln": "-MAAL---------AVVETPSGKDALAEGLLDLLRPAVQQLDLHVHSVRESQVELREHIDNLASELCRINEHQKVALDLDPYVKKLLNARRRVVLVNNILQNAQERLRRLNHNVAKETARRKTMLEASGAFTPRSPSKP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VQF9-1", "uniprot_id": "SNAPN_DROME", "id": "Q9VQF9-1", "name": "SNAPIN protein homolog", "aln": "MDSDSTVTSLEENTENFCTNPTRDILAEGITNLFKPTIERLDERVASTIQLQAELRGQLDALAAQLRDIEKAQSQIPEFADKVKELLNVKHKVTVISNVLVTSQERLTGLHKLIEKEQRRRQALLDS--ALSTNIS---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . :* :***: ::::*::::** :* :. : *.*** ::* **::* *:: *. :: **:***.:::*.::.*:* .:**** *:: : ** **:::*:: .. . ", "identical_positions": 36, "similar_positions": 51, "identity": "25.9%" }, { "cls_id": "homologset.agr.MGI:1333746", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q2PRI1-1", "uniprot_id": "Q2PRI1_DANRE", "id": "Q2PRI1-1", "name": "", "aln": "-MDNLTFRHSVLLVEGLKVTHQSSQPVFIVLFLSYIFAMISNITLIFLISTEKNLHDPMHFLFCNLPVNDIIGTTVILPRLMQDVLKEASERYISYTECVVQAYFVHVFTAACHYVLMIMAFDRYVAICNPLRYTAIMTNKMVIKLSASAWGLAIIVVTVMIGLTLRLSHCRS-TIENPFCDNASLFKLSCENVSINNAFGVVYSVIVACLSAISIFITYVKIATVCLASKNKALNSKAMKTCSTHLAVYLIMFVSGAIFIFLHRF--PEYAE-SRKLGSIMFHIVPPGLNPLVYGLQTKEIRQRFVKLCRRKTSTSLM", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q2PRH9-1", "uniprot_id": "Q2PRH9_DANRE", "id": "Q2PRH9-1", "name": "", "aln": "-MDNLTFTNSILLVEGLKVTPQSSQPVFIMFLLAYIFAMVSNIGLIFLISTEKNLHDPMHFLFCNLPLNDIMGTTVIMPRLLQDILTEASERYISYAECAIQAYFVHVFTAACHYVLMIMAFDRYVAICNPLRYTAIMTNKMVIGLSALAWGLAIIFVTIMVGLSLRLSRCRY-KIENPFCDNASLFKLSCENVSVNNVFGLVYTVIVLSLSALSIFVTYVKIATVCVTSKNKALNSKAIKTCSTHLAVYLIMFVTGAVFIFLHRF--PEYSD-NRKLASIMFHIVPPGLNPLVYGLQTKEIRQKVVKLWCRKKSMIT-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q2PRH7-1", "uniprot_id": "Q2PRH7_DANRE", "id": "Q2PRH7-1", "name": "", "aln": "-MDNLTFTNDFLLVEGLKVTYPSSYPIFILLFLFYIFAMGCNIGLIILIATEKKLHHPMHFLFCNLPVNDIIGTTVILPRLICDIFKQTSERSMTYVECVVQAYFVHIFTTASHTALVTMAYDRQVAICNPLLYTAVMTDKMVVKLSATAWTLPIIVVAVMIGLTVRLSRCRS-KIENPFCDNASLYKLSCENVAINNIFGIVYSVAALIISVALMVIAYARIVTACIISKSKALNSKAIKTCSSHIAVYLIMFVSCAIMIFFHRF--PEYSE-NRKLASIMFHIVPPGLNPIVYGLQTKEIRQIIVKRWWKNAVDKL-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q32PT6-1", "uniprot_id": "Q32PT6_DANRE", "id": "Q32PT6-1", "name": "", "aln": "-MDNRTFRYSTLLVEGLQITQQSSQLTFIFLLTVYVFSMVSNIGILIQILAEKSLHQPMYILFCHLPMSDIIGATVLIPRLLKDLLTDPSERYITYIECVLQAFFTHLYGTTSHTILMIMAFDRYVAICNPLRYPTIMNNKMIVKLSAGAWGAAIVLVGILIGLSVRLSHCRS-VIENHVCDNPSLFKLSCENTFINNVYGLTFTVVLLTSSLGWVVLTYLRIAMVCIKSKHKATNSKAIKTCTTHLTVYIITIIFGFVPIFLHRF--SEYTE-SRKFGNVMFHVVPPGLNPIIYGLQAKEIKDKMLKLCVK-KVNPS-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q90426-1", "uniprot_id": "Q90426_DANRE", "id": "Q90426-1", "name": "", "aln": "-MDNQTFRSSTLLMEGLQVANQYRQLAFIFVLIAYIFIMIFNIGLLIQISSEKSLHQPMYILLCNLPLNDVFGTTLLLPRLLRNILLEPSERYITYVECVIQAFFGHLYGTTCHTILMIMAFDRYVAICNPLRYPAVMTSNMVVHLSAAAWGVAVVLVGILIGLTVRLSFCRS-VIENPFCDNASLFKLSCESTAINNIYGLSFTVVLLTSSLGSIALTYLRIAIVCFKSKNKATNSKAIKTCSTHLAVYLIMMVSGLTTITLHRF--PELSD-SRKLSSIIKHIVPPCLNPIIYGLQVKEIRQRLFKLISKSKVNFM-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q2PRD7-1", "uniprot_id": "Q2PRD7_DANRE", "id": "Q2PRD7-1", "name": "Olfactory receptor", "aln": "MYPNGSVFPLVLTLQSLELPQMSIYPAFIFGLTTYLFILFCNLTIVITICLNRSLHKPMYILLLNMPINDTMAATNFFSQLLYSIWSQDTS--ISYPACLLQGFIVHLYGGASYVILTAMAYDRYIAICCPLRYGAIMNSNNLIKIITGMWVFNFTVITVLFSLLLPYKICRT-HMTDLFCYNPSIMKLMCEDTTVNNIIGLISLVLYHCIALSVVAFTYIHILITCVTNKQSDAKMKALQTCGTHLVVFLFLEFNTLFPLVAHRS--ESVPAYLRRVFSITVFVFPPIINPLVYGFKTKEIRQKMLTCFKRKMTSL--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q2PRE9-1", "uniprot_id": "Q2PRE9_DANRE", "id": "Q2PRE9-1", "name": "Olfactory receptor", "aln": "-MDNSTYFTTVILTGYIDIG-DIKYLCFVVLILLFAAIIVANLFIIGIICKEKSLHEPMYVFLCSLCANQLCGSFALFPFVLGNMLRSKTP-EVPLTVCHAQIFALYTYGQVEFCNLAMMSYDRYVAICHPLEYHRIMSPARTMTLIALGWSLQIIIFSLSFSVNVQLKLCGN-VLDKVWCDQYMLVKLACSDTTPNNIAGMTGIAVTIGAPLLLILFSYAKILRVCLKFKGQTAQ-KSLYTCILHLISLLNFAVGCSFELIQSRFGKLPMPAVVRVILSLYFLVCPPLFNPIMYGVRLANIKKALKKMICM-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0ACD6B7K1-1", "uniprot_id": "A0ACD6B7K1_DANRE", "id": "A0ACD6B7K1-1", "name": "Olfactory receptor", "aln": "-MENGANFTFIRLTGYLNLDFKMKYFLFAVLTVLYLTIICANSFLIGVICLAKILHKPMYMFLCSLFVNELYGSTALFPSLQVNLLLNDN--TISLVYCYLQIFCLCTYAMIDFCTLAVMSFDRYVSICYPLQYNKIMTPFRVGLLIALVWTYCFIQFFIFLSFKFKLQLCGN-VMEKVWCDNYLLVNLACSKSSLHNAYGIYLAVVTAVIPLTLIFYSYTRIIKICLSFSKEAKK-KALSTCTPHIISLLNFTLGCFFETLQSRFDEIRTPALIRVIVSLYLLMCQPLLNPILYAIRLKNIRLVCKNLVLSKIGIA--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q2PRG1-1", "uniprot_id": "Q2PRG1_DANRE", "id": "Q2PRG1-1", "name": "", "aln": "-MENYTSFNFMLFEN---LG-YIRYSLFVLGFVLYFAIIFFNVLIMLAVFLERTLHQPMYILISCLSMNSLFGTAGFFPRVLSDLLSETH--SISREACFSQSFVIFTYVANEFSILMLMAFDRFAAICKPLRYHSIVRPRFLACLIVINLNCIMILLCVAALLTTKLRMCGN-KLFKVYCHSYEVLKLSCDNILINNAFGLLLVIITTIIPLGLILLSYVKILIICQRSSAQFKG-KAYQTCIPHIVILLNFTIAVTCDTTLSRVVNLQIPVGLSVFLSLEFLIIPPVLNPLIYAFNLPDIRKKMISLIKPLK-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q2PRA7-1", "uniprot_id": "Q2PRA7_DANRE", "id": "Q2PRA7-1", "name": "", "aln": "-MDNNSSFSMFSLTALNGSR-SSRITIFSFALPGYFLTIFVNTLLILIIVLEKVLHQPMYIFLCNLCINGLYGATGFYPPLLYYLLSESN--VISLKECAIQSFAIFTYAIGEFTNLSVMAFDRYLAICRPLYYHNIMTTVTVWRLLTFIWMFPCCTAILLILMTLRFPICIK-KISKLYCETWVLERLVCGVDTAQFVFNG-ILTCAVNALVWFVFLSYINILVAC-KHSVQNHK-KFISTCLPHLIAFLNYVFWSLFSTLYELFGISSLSQEFKNFLSVTFMIIPPLINPVIYGIVLTPIRTKAKHVFQSFRPKHID", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8VGK5-1", "uniprot_id": "O1J21_MOUSE", "id": "Q8VGK5-1", "name": "Olfactory receptor 1J21", "aln": "MMKSNQSTVSEFILLGLPIQPEDQAVYFALFLAMYLTTVLGNLLIILLIRLDSHLHTPMYFFLSHLAFTDISFSSVTAPKMLMNMLTHSQS--ISHAGCVSQIYFFLLFGCIDNFLLTSMAYDRYVAICHPLHYTTIMSQSLCVLLVMVSWAFSSSNGLVHTLLFARLSLFRDNTVHHFFCDLSALLKLSSSDTTINELVILTLAVVVITVPFICILVSYGHIGATILRTPSIKGICKALSTCGSHLCVVSLYYGAIIGLYFFPSS---NNTNDKDVIVAVLYTVVTPMLNPFIYSLRNRDINGALRKTLSRRLCSH--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LIW9-1", "uniprot_id": "A0ABK0LIW9_RAT", "id": "A0ABK0LIW9-1", "name": "Olfactory receptor", "aln": "MMETNQSTVSEFILLGLPIQPEDQAVYSVLFLAMYMTTVLGNLLIILLIRLDSHLHTPMYFFLSHLAFTDISFSSVTAPKMLMNMLTHSQS--ISYAGCVSQIYFFLLFGCIDNFLLTSMAYDRYVAICHPLHYTTVMSQSLCVLLVMISWVFSSTNGLVHTLLFARLSHFKDNTVHHFFCDLSALLKLSISDTTINELVILTLAVVVITVPFICILISYGHIGATILRTPTIQGICKALSTCGSHLCVVFLYYGAIIGLYFFPSS---NNTNAKDVIASVLYTVVTPMLNPFIYSLRNRDMKGALKNTLSRRLCSH--", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : : * :: : ** **:.:: : . : . : : :. * * : : * *::** :** ** * :: : : . : . * : .* : : :* .* * ** *: . . : : * :**.:*.. :. ", "identical_positions": 28, "similar_positions": 49, "identity": "8.78%" }, { "cls_id": "homologset.agr.MGI:1333747", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9I8Z0-1", "uniprot_id": "Q9I8Z0_DANRE", "id": "Q9I8Z0-1", "name": "", "aln": "------MYYFAYFLTFYFQPVQNKADMSLSQNSSSVYPEYFFIIGLSGIHNSNYYYMFLCITYFVTVTGNSLVLLLIALYRSLHSPKYIGVFNLALADFGETNALIPNMMKTFLFDSQYISYNACLANMFFVHFFSTVQSFTLVVLAYDRFIAIFLPLRYHAIVNYTFMYFVFSIIWVFNASIVAFAVSLITRLSFCESNKVNGYYCDYGPVYRLACNDNSICASMAQLSAALYVVAPVIIIVLSYLGIFLALSKITTWEGRLKALKTCVSHLLLVGSFFLPIICIFIATSTNSLSLNARVISTSLAHALPPMLHPIIYVLNTAEIKDIIIKIVRNKCLPVRKNILKLRK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9I8Z1-1", "uniprot_id": "Q9I8Z1_DANRE", "id": "Q9I8Z1-1", "name": "", "aln": "--------------------------MSLYENNSIVRPEYFFIIGLSGIPNSSYYYIFLFIIYCITVIGNSLVLLIIALDRSLHSAKYLCVFNLALADFGETNAVIPNMLKTFLFDSQYISYNACLANMFFVNYFINVQSATLVVLAFDRVIAICLPLRYHSIVNNIVMLIVFFGIWTLNTLVVALSVSLMTRLSICKSNVVESYYCDYGPVLRLACNDSTVNKIITNVIAVMSLVAPVILIVLSYLGIFFALSKITTWEGRLKALKTCVSHLLIVGLFFLPVICIFIASSTSTLTPNVRIISTSLSFTLPPMLNPIIYVLNTAEIKDTIRKKFKKRIFT----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AC58HBV7-1", "uniprot_id": "A0AC58HBV7_DANRE", "id": "A0AC58HBV7-1", "name": "", "aln": "MFLFFMLTFLKLAQNIKRKTAMSSVNASFSQNISIVRPEYFFISGLSGIPYSSYYYIFLFVVYFISVIGNSVVLLIIAVDRSLHSPKYIGVFNLALADIGETNALIPNMMKTFLFNSQYISYNGCMANMFFVFLFNSIQSFTLVALAYDRFIAICLPLRYHAIVNNTSMILIFLAIWAFNSSVVASMVSMITRLSICKSNVIPSYFCDHGPIFRLACNDIKINEFFAFFISILYLTMPMVIIALSYLNIFLALIKITTWEGRLKALKTCVSHLLLVGIFFLPLLCTYIAQVLLALTPNARVISTSLSYAIPPMLNPIIYVLNTAEIKYIIRKLFKRRLRSVSDNISK---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M2B4K9-1", "uniprot_id": "A0A8M2B4K9_DANRE", "id": "A0A8M2B4K9-1", "name": "", "aln": "-----MQSYRKLARNNKSKSAMSSVNASFSQNISIVHPENFFIIGLTGIQHSGYYYIFLFFTYFISVIGNSVVLLIIALERNLHSAKYIGVFNLALADIGETSALIPNMMKNFLFDSQYISYNGCMANMFFVFLFSSMQSFTLVVMAYDRLIAICLPLRYHAIVNNTSMILMTLAIWAFNTFVVALMVSLINRLSFCESNMIQSYFCDHGPVFRLACNDNSMNKIMAYVISVLYILAPMVVIVFSYLAIFLALIKITTWEGRLKALKTCVSHLLLVGIFFLPVCCTYIAQVLLYLTPNARIISTSFSYAVPPVLNPIIYVLNTAEIKDIIKKMIKNKSAPIRENISK---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O42169-1", "uniprot_id": "O42169_DANRE", "id": "O42169-1", "name": "", "aln": "---------------------MNFLNESFYQNISFVHPQYFYIIGLSGTPYSSYFYVFLFITYFITLFGNSVVLLIIALDRSLHSPKYIGVFNLALADIGETNALIPNMVKTFLFDSQYISYNACLANMFFVFLFSSIQSFALLVLAFDRFVAICLPLRYHALVNNTTMLLAFAAVWAFNSFVVALMVSLITRLSFCQSNMIQSYFCDHGPVYRIACNDFSINKFMAFLITGLYLVIPLFLIVLSYLGIFLALTKITTFEGRIKALKTCVSHLLLVGTLFLPLFCTYFAQLLLSLSPNARVICTSLAYTIPPMLNPIIYVLNTAEIKDIIWKVFKNKSVAVES-ISK---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB13A8W9-1", "uniprot_id": "A0AB13A8W9_DANRE", "id": "A0AB13A8W9-1", "name": "", "aln": "---------------------MSSLNASSYKNTSIVHPEYFFISGLSGIPYSSYYYVFLFITYFITIIGNSVVLLIIAFERSLHSPKYIVVFNLALADIGETNALIPNMMKTFLFDSQYISYNACLVNMFFVFLFSTMQSFTLVVLAYDRFVAICLPLRYHAIVNNSSITLILSAKWAFNSSMVALMVSLITRISFCDSNVIQSYFCDHGPVYRLACNDNSINRFMGSFITCLYLVVPLAIIILSYIGIFLALNKITTWESRLKALKTCVSHLLLVGIYFLPMSCTYIAAWLLALAPNARVITTSLAYTISPMLNPIIYVLNTAEIKDLLRKMFKNKSAPSKDNIAK---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0ABK0M1N1-1", "uniprot_id": "A0ABK0M1N1_RAT", "id": "A0ABK0M1N1-1", "name": "Olfactory receptor", "aln": "----------------------------MDGDNQTTVTEFILLGLTEQSEKEEIVFGMFLWMYLVTISGNLLIILAISCDPHLHTPMYFFLANLSSVDISAPSVIVPKALVNHMLGSKSISYMGCMIQIYFFITFSNMDGFLLSVMAYDRYVAICHPLHYTMMMRPRLCVLLVAVSWVITNLHALLHTLLMVRLTFCSHNAVHHFFCDPYPIMKLSCSDTFINDLMVFTIGGLVFLTPFTCIIVSYAYIFSKVLKLKSAHGIRKSLSTCGSHLTVVSLFYGAILGIYMHPSSTYTVQDT--VATVIFTVVTPMVNPFIYSLRNRDIKGALRKIILRP-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VGG9-1", "uniprot_id": "Q8VGG9_MOUSE", "id": "Q8VGG9-1", "name": "Olfactory receptor", "aln": "----------------------------MDGDNQTIVTEFILLGLTRQSEKEEVVFGLFLWMYLVTISGNLLIILAISCDPHLHTPMYFFLANLSSVDISAPSVIVPKALVNHMLGSKSISYTGCMTQIYFFITFSNMDGFLLSVMAYDRYVAICHPLHYTMMMRPRLCVLLVAISWAITNLHALLHTLLMVRLTFCSHNAVHHFFCDPYPILKLSCSDTFINDLMVFTIGGLVFMTPFTCIIVSYAYIFSKVLKLKSAHGIRKALSTCGSHLTVVSLFYGAILGIYMHPSSTYTVQDT--VATVIFTVVTPMVNPFIYSLRNRDIKGALRKIILRS-------------", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . .: : : . : :: * ::: ** :::* *: **:. *: : **: .*:. ...::*: : ..::.*: *** .*: :::*. * .::. * .:*:** :** **:* ::. : *.:. . . :: *:::*. * : ::** *: :::*.* : : : . *. * .** ** : *:.: .. *:*.** *** :*. : .: :: :. : * : .:.*:::*:** *.. :** : * . . ", "identical_positions": 61, "similar_positions": 114, "identity": "17.43%" }, { "cls_id": "homologset.agr.MGI:1333748", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P0C7N1-1", "uniprot_id": "OR8U8_HUMAN", "id": "P0C7N1-1", "name": "Olfactory receptor 8U8", "aln": "MAHINCTQATEFILVGLTDHQELKMPLFVLFLSIYLFTVVGNLGLILLIRADTSLNTPMYFFLSNLAFVDFCYSSVITPKMLGNFLYKQNVISFDACATQLGCFLTFMVSESLLLASMAYDRYVAICNPLLYMVVMTPGICIQLVAVPYSYSFLMALFHTILTFRLSYCHSNIVNHFYCDDMPLLRLTCSDTRFKQLWILACAGITFICSVLIVFVSYMFIIFAILRMSSAEGRRKAFSTCSSHMLAVTIFYGTLIFMYLQPSSSHSLDADKMASVFYTVIIPMLNPLIYSLRNKDVKDALKKVIINRNHAFIFLKLRK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8VFL0-1", "uniprot_id": "Q8VFL0_MOUSE", "id": "Q8VFL0-1", "name": "Olfactory receptor", "aln": "MAQINCTQVTEFILVGLTDRKELKMPLFVVFLFIYLFTAIGNLGLILVIRTDARLNTPMYFFLSNLAFVDFCYSSVITPKMLGNFLYSKNAISFNACAAQLGCFLTFMVSECLLLASMAYDRYAAICNPLLYMVTMSPGICIQLVVVPYSYSFLMALIHTLLTFRLSYCHSNIINHFYCDDMPLLRLTCSDTHYKQLSILACAGITFISSVLIVSVSYMFIISAILRMRSAEGRRKAFSTCSSHMMAVSIFYGTLIFMYLQPSSDHSLDTDKMASVFYTVIIPMLNPLIYSLRNKDVKDALKRVMDNRNQTSIFRELRK", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:*****.**********::********:** *****.:*******:**:*: *********************************.:*.***:***:************.***********.**********.*:********.***********:**:************:******************::*** **********.***** ******* ***** ****************:**:***************.****:********************************:*: ***:: ** :***", "identical_positions": 275, "similar_positions": 35, "identity": "86.21%" }, { "cls_id": "homologset.agr.MGI:1333749", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VGL8-1", "uniprot_id": "Q8VGL8_MOUSE", "id": "Q8VGL8-1", "name": "Olfactory receptor", "aln": "MMLLSLNQTGVTEFVLEGFSEHPGLRLFLTGCFLTLYMMALMGNIVIIALVTSSTGLHNPMYFFLCNLATTDIVCTSSVIPKALIGLVSEENIITFKGCMAQLFFLAWATSAELLLLTVMAYDRYVAICFPLHYSSRMSPQLCGALAVGVWSISAVNASVHTGLMTRLSFCGPKVITHFFCEIPPLLLLSCSSTYINSVMTLVADVFLGGINFMLTLLSYGFIIASILRMRSAEGKRKAFSTCSSHLIVVSVYYSSVFCAYISPASSYSPERSKFTSVLYSVVSPTLNPLIYTLRNKDVKLALGRMLASFSH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LE52-1", "uniprot_id": "A0ABK0LE52_RAT", "id": "A0ABK0LE52-1", "name": "Olfactory receptor", "aln": "--MVSPNQTVVTEFVLQGFSEHPGLRLLLTGCFLSLYTMALMGNIVIIALVTSSTGLHSPMYFFLCNLATMDIICTSSVLPKALVGLLSEENTISFKGCMAQLFFLLWSGSSELLLLTVMAYDRYVAICFPLHYSSRMSRQLCGALAIGVWSICAVNASVHTGLMTQLSFCGPKVITHFFCEIPPLLLLSCSSTYVNSIMTLVADAFYGGINFVLTLLSYGCIIASILCMHSAEGKKKAFSTCSSHLIVVAMYYSSVFFTYISPASSYSPERSKFTSVLYSVLSPTLNPLIYTLRNKDVKLALSRILGSFSH", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::* *** ******:**********:******:** ********************.*********** **:*****:****:**:**** *:*********** *: *:*************************** *******:*****.************:****************************:**:******.* *****:******* ****** *:*****:*************::****** :**********************:********************.*:*.****", "identical_positions": 269, "similar_positions": 29, "identity": "86.22%" }, { "cls_id": "homologset.agr.MGI:1333750", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VFE6-1", "uniprot_id": "Q8VFE6_MOUSE", "id": "Q8VFE6-1", "name": "Olfactory receptor", "aln": "MSKGRENETGVSEFLLLGITNDPQQQQILFWAFLCMYLVTVAGNTLIFLAIISDPRLHTPMYFFLANLSFVDVCFTTNLIPRLLAGHVAGTRTISYVHCLTQTYFLISFANVDTFLLAAMALDRFVAICYPLQYHTIITPQLCVGLAAVVWMCSALISLMHTLLMSRLSFCSSIPEISHFYCDAYLLMKLACSDTRVNQLVFLGAVVLFVAPCILIVVSYVRITMVVLQIPSAKGRHKTFSTCSSHLSVVTLFYGTVLGIYIRPPDSFSTQDTVATIMYTVVTPMLNPFIYSLRNKDMKESVTRLLNRGSKSS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4AB86-1", "uniprot_id": "D4AB86_RAT", "id": "D4AB86-1", "name": "Olfactory receptor", "aln": "MSKWGENETRASGFLLLGITNDPQQQQILFWAFLCMYLVTVAGNTLIFLAISSDPRLHTPMYFFLANLSFVDVCFTTNLIPRLLASHVSGTEIISYAHCLTQMYFLISFANVDTFLLAAMALDRFVAICYPLQYHTIITPQLCVGLAAVVWICSGLISLVHTLLMNRLTFCSSIPEISHFYCDAYLLMKLACSDTRINQLVFLGAVVLFVAPCILIVFSYVRIAMAVFQIPSAKGRHKAFSTCSSHLTVVILFYGTVLGIYIRPPDSFSTQDTVATIMYTVVTPMLNPFIYSLRNKDMKQTVTRLFNRGSQSS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3ZL22-1", "uniprot_id": "D3ZL22_RAT", "id": "D3ZL22-1", "name": "Olfactory receptor", "aln": "MSKWGENETGVIEFLLLGITNDPQQQRILFWAFLCMYLVTVAGNTLIFLAISSDPHLHTPMYFFLANLSFDDVCFTTNIIPRLLAGHVSGTETISYAYCLTQMYFLISFGNVDTFLLAAMALDRFVAICYPLQYHTIITPRLCVGLASVVWISSGLIALVHTLLMSRLTFCSSIPEISHFYCDAYLLMKLACSDTRINQLVFLGAVVFFVAPCILIVFSYVRIAMAVFQIPSAKGRHKAFSTCSSHLTVVILFYGTVLGIYIRPPDSFSTQDTVATIMFTVVTPMLNPFIYSLRNKDMKETVTRLLHRGSKSS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I5ZPR8-1", "uniprot_id": "A0A8I5ZPR8_RAT", "id": "A0A8I5ZPR8-1", "name": "Olfactory receptor", "aln": "MSKWGENETGVSEFLLLGITNDPQQQRILFWAFLCMYLVTVAGNTLIFMAISSDPRLHTPMYFFLANLSFNEVCFTTNLIPRLLASHVSGIGTISYAHCLTQMYFLISFADVDFCLLTAMALDRFVAICYPLQYHTIITPRLCVGLAAVVWISCGLIALVHTLFMSRLTFCSSIPEISHFYCDPYLLMKLACSDTRVDQLLFLGAVVLFVAPCILIVFSYARIAVAVFQIPSAKGRHKAFSTCSSHLTVVILFYGTVLGIYIRPPDSFSTQDTVATIMYTVVTPMLNPFIYSLRNKDMKETVTRLLHRCSKSS", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** **** . *************:*********************:** ***:************** :******:******.**:* ***.:**** ******.:** **:**********************:******:***:...**:*:***:*.**:**************.************::**:******:*********.**.**::.*:**********:********:** ***************************:********************::****::* *:**", "identical_positions": 255, "similar_positions": 43, "identity": "81.47%" }, { "cls_id": "homologset.agr.MGI:1333751", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0M672-1", "uniprot_id": "A0ABK0M672_RAT", "id": "A0ABK0M672-1", "name": "", "aln": "MAVTLGRNYTFVSEFILIGFSTFPHLQLMFFLLFLLMYLVTLLGNLLIMVTIWSEHSLHTPMYLFLCALSISEIFYTFAIIPRMLADLLSALHSIALLACASQMFFSFTFGFTHSFLLTVMGYDRYVAICHPLRYNVLMSPRGCACLVAWSWVGGSVMGTVVTTAVFNLTFCGPNEIHHFTCHVPPLLKLACGENVLEVAKGVETVCITALLGCFLLILLSYAFIVATILKIPSSEGRHKAFSTCASHLTVVVVHYGFASVIYLKPKGPKSLEGDTLMGITYTVLTPFLSPIIFSLRNKELKNAMKKAFLSKLYPEKI---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "K7N6Q1-1", "uniprot_id": "K7N6Q1_MOUSE", "id": "K7N6Q1-1", "name": "", "aln": "---MLGLNYTFVSEFILIGFSTFPHLQLMFFLLFLLMYLFTLLGNLLIMTTIWSEHSLHTPMYLFLCALSISEIFYTFAIIPRMLADLLTTLHSIAFLACASQMFFSFTFGFTHSFLLTVMGYDRYVAICHPLRYNVLMSPRGCACLVAWSWVGGSFMGTVVTTAIFNLTFCGPNEIHHFTCHVPPLLKLACGENVLEVAKGVEIVCITALLGCFLLILLSYAFIVVTILKIPSAEGRHKAFSTCASHLTVVVVHYGFASVIYLKPKGPKSLEGDTLMGITYTVLTPFLSPIIFSLRNKELKNAMKKIFLSKLYPEKI---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0M7B6-1", "uniprot_id": "A0ABK0M7B6_RAT", "id": "A0ABK0M7B6-1", "name": "", "aln": "MAVTLGLNHTFVSEFILIGFSTFPHLQLMFFLLFLLMYLFTLLGNLLIMATIWSEHSLHTPMYLFLCALSISEIFYTFAIIPRMLADLLSALHSIALLACASQMFFSFTFGFTHSFLLTVMGYDRYVAICHPLRYNVLMSPRGCACLVAWSWVGGSFMGTVVTTAIFNLTFCGPNEIHHFACHVPPLLKLACGKNVLAVAKGVGMVCITALLGCFLLILLSYAFIVATILKIPSAEGRHKAFSTCASHLTVVVVHYGFASVIYLKPKGPKSLGGDTLMGITYTVLTPFLSPIIFSLRNKELKNAMKKAFLSKLYPEKM---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y4A9-1", "uniprot_id": "O10H1_HUMAN", "id": "Q9Y4A9-1", "name": "Olfactory receptor 10H1", "aln": "---MQRANHSTVTQFILVGFSVFPHLQLMLFLLFLLMYLFTLLGNLLIMATVWSERSLHTPMYLFLCALSVSEILYTVAIIPRMLADLLSTQRSIAFLACASQMFFSFSFGFTHSFLLTVMGYDRYVAICHPLRYNVLMSPRGCACLVGCSWAGGLVMGMVVTSAIFHLAFCGHKEIHHFACHVPPLLKLACGDDVLVVAKGVGLVCITALLGCFLLILLSYAFIVAAILKIPSAEGRNKAFSTCASHLTVVVVHYGFASVIYLKPKSPQSLEGDTLMGITYTVLTPFLSPIIFSLRNKELKVAMKKTFFSKLYPEKNVMM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NGA6-1", "uniprot_id": "O10H5_HUMAN", "id": "Q8NGA6-1", "name": "Olfactory receptor 10H5", "aln": "---MQGLNHTSVSEFILVGFSAFPHLQLMLFLLFLLMYLFTLLGNLLIMATVWSERSLHMPMYLFLCALSITEILYTVAIIPRMLADLLSTQRSIAFLACASQMFFSFSFGFTHSFLLTVMGYDRYVAICHPLRYNVLMSLRGCTCRVGCSWAGGLVMGMVVTSAIFHLAFCGHKEIHHFFCHVPPLLKLACGDDVLVVAKGVGLVCITALLGCFLLILLSYAFIVAAILKIPSAEGRNKAFSTCASHLTVVVVHYGFASVIYLKPKGPQSPEGDTLMGITYTVLTPFLSPIIFSLRNKELKVAMKKTCFTKLFPQNC---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O60403-1", "uniprot_id": "O10H2_HUMAN", "id": "O60403-1", "name": "Olfactory receptor 10H2", "aln": "---MLGLNHTSMSEFILVGFSAFPHLQLMLFLLFLLMYLFTLLGNLLIMATVWSERSLHTPMYLFLCVLSVSEILYTVAIIPRMLADLLSTQRSIAFLACASQMFFSFSFGFTHSFLLTVMGYDRYVAICHPLRYNVLMSPRGCACLVGCSWAGGSVMGMVVTSAIFQLTFCGSHEIQHFLCHVPPLLKLACGNNVPAVALGVGLVCIMALLGCFLLILLSYAFIVADILKIPSAEGRNKAFSTCASHLIVVIVHYGFASVIYLKPKGPHSQEGDTLMATTYAVLTPFLSPIIFSLRNKELKVAMKRTFLSTLYSSGT---", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:: :::***:***.*******:*********.*********.*:***:*** *******.**::**:**.***********:: :***:***********:******************************* ***:* *. **.** .** ***:*:*:*:*** :**:** ************.:* ** ** *** *****************. ******:***:********** **:**************.*:* *****. **:******************* ***: ::.*:.. ", "identical_positions": 236, "similar_positions": 49, "identity": "73.52%" }, { "cls_id": "homologset.agr.MGI:1333752", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z2V5-1", "uniprot_id": "HDAC6_MOUSE", "id": "Q9Z2V5-1", "name": "Protein deacetylase HDAC6", "aln": "-------MTSTGQDSS-TRQRKSRHNPQSP-------LQESSATLKRGGKKCAVPHSSPN----LAEVKKKGK--MKKLSQPAEEDLVVGLQGLDLNPETRVPVGTGLVFDEQLNDFHCLWDDSFPESPERLHAIREQLILEGLLGRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGE-LRVLAETYDSVYLHPNSYSCACLATGSVLRLVDALMGAEIRNGMAVIRPPGHHAQHNLMDGYCMFNHLAVAARYAQKKH--RIQRVLIVDWDVHHGQGTQFIFDQDPSVLYFSIHRYEHGRFWPHLKASNWSTIGFGQGQGYTINVPWNQT-------------------------------GMRDADYIAAFLHILLPVASEFQPQLVLVAAGFDALHGDPKGEMAATPAGFAHLTHLLMGLAGGKLILSLEGGYNLRALAKGVSASLHTLLGDPCP-MLESCVVPCASAQTSIYCTLEALEPFWEVLERSVETQEEDEVEEAVLEEEEEEG-GWEATALPMDTWP---------------------LLQNRTGL---------VYDEKMMSHCNLWDNHHPETPQRILRIMCHLEEVGLAARCLILPARPALDSELLTCHSAEYVEHLRTTEKMKTRDLHREGANFDSIYICPSTFACAKLATGAACRLVEAVLSGEVLNGIAVVRPPGHHAEPNAACGFCFFNSVAVAARHAQIIAGRALRILIVDWDVHHGNGTQHIFEDDPSVLYVSLHRYDRGTFFPMGDEGASSQVGRDAGIGFTVNVPWNGPRMGDADYLAAWHRLVLPIAYEFNPELVLISAGFDAAQGDPLGGCQVTPEGYAHLTHLLMGLAGGRIILILEGGYNLASISESMAACTHSLLGDPPPQLTLLRPPQSGALVSISEVIQVHRKYWRSLRLMKMEDKEECSSSRLVIKKLPPTASPVSAKEMTTPKGKVPEESVRKTIAALPGKESTLGQAKSKMAKAVLAQGQ--------------------------------------------------------SSEQAAKGTTLDLATSKETVGGATTDLWASAAAPENFPNQTTS-VEALGETEP--TPPASHTNKQTTGASPLQGVTAQQSLQ--LGVLSTLELSREAEEAHDS----EEGLLGEAAGGQDMNSLMLTQGFGDFNTQDVFYAVTPLSWCPHLMAVCPIPAAGLDVSQPCKTCGTVQENWVCLTCYQVYCSRYVNAHMVCHHEASEHPLVLSCVDLSTWCYVCQAYVHHEDLQDVKNAAHQNKFGEDMPHSH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6GM68-1", "uniprot_id": "HDAC6_RAT", "id": "A0A8I6GM68-1", "name": "Protein deacetylase HDAC6", "aln": "-------MTSTGQDSS-TRQRKSRHNPQSP-------LQDSSATLKRGGKKGAVPHSSPN----LAEVKKKGK--MKKLSQPAEEDLIVGLQGLDLNSETRVPVGTGLVFDEQLNDFHCLWDDSFPENPERLHAIKEQLILEGLLGRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGE-LRVLAGTYDSVYLHPNSYSCACLATGSVLRLVDAVMGAEIRNGMAVIRPPGHHAQRSLMDGYCMFNHLAVAARYAQKKH--RIQRILIVDWDVHHGQGTQFIFDQDPSVLYFSIHRYEHGRFWPHLKASNWSTTGFGQGQGYTINVPWNQVSFCSHKLSLACFPRGSREMTDYYIAFLCLQVGMRDADYIAAFLHILLPVAFEFQPQLVLVAAGFDALHGDPKGEMSATPAGFAHLTHFLMGLAGGKLILSLEGGYNLHALAKGVSGSLHTLLGDPCP-MLESPVAPCASAQTSISCTLEALEPFWEVLERSVEPQDEDEVEGDMLEDEEEEG-HWEATALPMDTWP---------------------LLQNRTGL---------VYDERMMSHCNLWDNHHPETPQRILRIMCHLEEVGLAARCLILPARPALDSELLTCHSAEYVERLRATEKMKTRDLHREGANFESIYICPSTFACAQLATGAACRLVEAVLSGEVLNGIAIVRPPGHHAEPDAACGFCFFNSVAVAARHAQVIAGRALRILIVDWDVHHGNGTQHIFEEDPSVLYVSLHRYDRGTFFPMGDEGASSQVGRAAGTGFTVNVPWNGPRMGDADYLATWHRLVLPIAYEFNPELVLISAGFDAAQGDPLGGCQVTPEGYAHLTHLLMGLAGGRIILILEGGYNLTSISESMAACTHSLLGDPPPQLTSLRPPQSGALASISEVIQVHRKYWRSLRLMKMEDKEERSSSRLVIKKLPQSASPVSAKGMTTPKGKVLEAGMRKPTAALPTKESTLGQAKAKTAKALLAQGQ--------------------------------------------------------SSEQAAKGTTLDLATSKDTVGGATTDQCASVAATENSANQTTSGEEASGETESFGTSPSSNASKQTTGASPLHGAAAQQSPE--LGLSSTLELSSEAQEVQES----EEGLLGEAAGGQDMNSLMLTQGFGDFNTQDVFYAVTPLSWCPHLMAVCPIPAAGLDVSQPCKTCGSVQENWVCLTCYQVYCSRYVNAHMVCHHEASEHPLVLSCVDLSTWCYLCQAYVHHEDLQDVKNAAHQNKFGEGMPHLQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UBN7-1", "uniprot_id": "HDAC6_HUMAN", "id": "Q9UBN7-1", "name": "Protein deacetylase HDAC6", "aln": "-------MTSTGQDSTTTRQRRSRQNPQSP-------PQDSSVTSKRNIKKGAVPRSIPN----LAEVKKKGK--MKKLGQAMEEDLIVGLQGMDLNLEAEALAGTGLVLDEQLNEFHCLWDDSFPEGPERLHAIKEQLIQEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGE-LRVLADTYDSVYLHPNSYSCACLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQKH--RIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQGQGYTINVPWNQV-------------------------------GMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQGDPKGEMAATPAGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDPCP-MLESPGAPCRSAQASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEEEG-PWEPPVLPILTWP---------------------VLQSRTGL---------VYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCHSAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACRLVEAVLSGEVLNGAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAAWHRLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEGGYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMKVEDREGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGASESQAPGEENLLGEAAGGQDMADSMLMQGSRGLTDQAIFYAVTPLPWCPHLVAVCPIPAAGLDVTQPCGDCGTIQENWVCLSCYQVYCGRYINGHMLQHHGNSGHPLVLSYIDLSAWCYYCQAYVHHQALLDVKNIAHQNKFGEDMPHPH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "M9PJN5-1", "uniprot_id": "M9PJN5_DROME", "id": "M9PJN5-1", "name": "Protein deacetylase HDAC6", "aln": "MSPPIVTRRSAQQAKIQTRAMASKSKTGTTGAATAAGGTGSSSGSISGGFNAADPRKSNKPNAALLEAKRRARNNMLKNQGCGSQESVTDIFQNAVNSKSLVRKPTALIYDESMSQHCCLWDKEHYECPERFTRVLERCRELNLTERCLELPSRSATKDEILRLHTEEHFERLKETSGIRDDERMEELSSRYDSIYIHPSTFELSLLASGSTIELVDHLVAGKAQNGMAIIRPPGHHAMKAEYNGYCFFNNVALATQHALDVH--KLQRILIIDYDVHHGQGTQRFFYNDPRVVYFSIHRFEHGSFWPHLHESDYHAIGSGAGTGYNFNVPLNAT-------------------------------GMTNGDYLAIFQQLLLPVALEFQPELIIVSAGYDAALGCPEGEMEVTPACYPHLLNPLLRLADARVAVVLEGGYCLDSLAEGAALTLRSLLGDPCPPLVETVPLPRAELAQALLSCIAVHRPHWRCLQLQQTYDCVELQDRDKEEDLHTVLRHWIGGPPPMDRYPTRDTAIPLPPEKLTSNAARLQVLRAETKLSVPSFKVCYAYDAQMLLHCNLNDTGHPEQPSRIQHIHKMHDDYGLLKQMKQLSPRAATTDEVCLAHTRAHVNTVRRLLGREPKELHDAAGIYNSVYLHPRTFDCATLAAGLVLQAVDSVLRGESRSGICNVRPPGHHAEQDHPHGFCIFNNVAIAAQYAIRDFG-LERVLIVDWDVHHGNGTQHIFESNPKVLYISLHRYEHGSFFPKGPDGNFDVVGKGAGRGFNVNIPWNKKGMGDLEYALAFQQLIMPIAYEFNPQLVLVSAGFDAAIGDPLGGCKVTAEGYGMLTHWLSALASGRIIVCLEGGYNVNSISYAMTMCTKTLLGDPVP------TPQLGATALQKPPTVAFQSCVESLQQCLQVQRNHWRSLEFVGRRLPR--DPVVGE---NNNEDFLTASLRHLNISNDDATAAAGGLAGDRPDCGDERPS--------------------------------------------------------GSKPKVKVKTLSDYLAENKEALEQSEMFAVYPLKTCPHLRLLRPEEAPRSLDSGAECSVCGSTGENWVCLSCRHVACGRYVNAHMEQHSVEEQHPLAMSTADLS-------VWCYACSAYVDHPRLYAYLNPLHEDKFQEPMAWTHGCAWREDGC--YATGPDGRDEDDDDDNGAGSSICLRLERNNX-----PLAIRVLDALTDYLCALCPPLR-----HLIHFLAEHLWPLLERIYLNLLHYFLAH--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53973-1", "uniprot_id": "HDA1_YEAST", "id": "P53973-1", "name": "Histone deacetylase HDA1", "aln": "-MDSVMVKKEVLENPDHDLKRKLEENKEEE---------NSLSTTSKSKRQVIVPVCMPK-----------------IHYSPLKTGLCYDVR---MRYHAKIFTSYFEYIDPHPEDPRRIYRIYKILAENGLINDPTLSGVDDLGDLMLKIPVRAATSEEILEVHTKEHLEFIESTEKMSREE-LLKETEKGDSVYFNNDSYASARLPCGGAIEACKAVVEGRVKNSLAVVRPPGHHAEPQAAGGFCLFSNVAVAAKNILKNYPESVRRIMILDWDIHHGNGTQKSFYQDDQVLYVSLHRFEMGKYYPGTIQGQYDQTGEGKGEGFNCNITWPVG-------------------------------GVGDAEYMWAFEQVVMPMGREFKPDLVIISSGFDAADGDTIGQCHVTPSCYGHMTHMLKSLARGNLCVVLEGGYNLDAIARSALSVAKVLIGEPPDELPDPLSDPKPEVIEMIDKVIRLQSKYWNCFRRRHANSGCNFNEPINDS----------------------------------------------------------IISKNFPLQKAIRQQQQHYLSDEFNFVTLPLVSMDLPDNTVLCTPNISESNTIIIVVHDTSDIWAKRNVISGTIDLSSSVIIDNSLDFIKWGLDR--------------------KYGIIDVNIPLTLFEPDNYSGMITS-----------------QEVLIYLWDNYIK-----YFPSVAKIAFIGIGDSYSGIVHLLG--------HRDTRAVTKTVINFLGDKQ---------LKPLVPLVDETLSEWYFKNS---------LIFSNNSHQCWKENESRKPRKKFGRVLRCDTDGLNN-----------------------------------------IIEERFEEATDFILDSFEEWSDEE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. : . : * . : * : . .: :. .: * .: :: : : .* :.: * * .:*:: :*: *::: :: *. : * : : **:*:: .:: : *. *..:. . :: .. :*.:*::******* .*:*:*.::*:*:: . : ::*::*:*:*:***:*** * :* *:*.*:**:* * ::* .:: * * * *:. *:. *: :.:*: * ::::*:. **:*:*:::::*:** * . *: .**: : :: : * ** ..: : ***** * ::*... : *:*:* : :. * . : : .*. : : : . . .: : : : : ...: : . .* . ... : : : . :* :*: : : * *. * * : *: .:** ** : * . ..: ::.: * .. * : : .. : : : ::*:. * .: : .: * .: : : : **:: .* * . .. . : . . ", "identical_positions": 107, "similar_positions": 220, "identity": "8.22%" }, { "cls_id": "homologset.agr.MGI:1333753", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WU78-1", "uniprot_id": "PDC6I_MOUSE", "id": "Q9WU78-1", "name": "Programmed cell death 6-interacting protein", "aln": "MASFIWVQLKKTSEVDLAKPLVKFIQQTY-PSGGEEQAQYCRAAEELSKLRRSALGRPLDKHEGALETLLRYYDQICSIEPKFPFSENQICLTFTWKDAFDKGSLFGGSVKLALASLGYEKSCVLFNCAALASQIAAEQNLDNDEGLKTAAKQYQFASGAFLHIKDTVLSALSREPTVDISPDTVGTLSLIMLAQAQEVFFLKATRDKMKDAIIAKLANQAADYFGDAFKQCQYKDTLPK-----EVFPTLAAKQCIMQANAEYHQSILAKQQKKFGEEIARLQHAAELIKNVASRYDEYVNVKDFSDKINRALTAAKKDNDFIYHDRVPDLKDLDPIGKATLVKPTPVNVPVSQKFTDLFEKMVPVSVQQSLAVFSQRKADLVNRSIAQ-MREATTLANGVLASLNLPAAIEDVSGDT-VPQSILTKSTSVVEQGGIQTVDQLIKELPELLQRNREILEESLRLLDEEEATDNDLRAKFKDR-WQRTPSNDLYKPLRAEGAKFRAVLDKAVQADGQVKERYQSHRDTIALLCKPEPELNAAIPSANPAKTMQGSEVVSVLKSLLSNLDEIKKERESLENDLKSVNFDMTSKFLTALAQDGVINEEALSVTELDRIYGGLTSKVQESLKKQEGLLKNIQVSHQEFSKMKQSNNEANLREEVLKNLATAYDNFVELVANLKEGTKFYNELTEILVRFQNKCSDIVFARKTERDELLKDLQQSIAREPSAPSIPPPAYQS---SPAAGHAAAPPTPAPRTMPPAKPQPPARPPPPVLPANRVPPASAAAAPAGVGTASAAPPQTPGSAPPPQAQGPPYPTYPGYPGYCQMPMPMGYNPYAYGQYNMPYPPVYHQSPGQAPYPGP--QQPTYPFPQPP--QQSYYPQQ-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9QZA2-1", "uniprot_id": "PDC6I_RAT", "id": "Q9QZA2-1", "name": "Programmed cell death 6-interacting protein", "aln": "MASFIWVQLKKTSEVDLAKPLVKFIQQTY-PSGGEEQAQYCRAAEELSKLRRSALGRPLDKHEGALETLLRYYDQICSIEPKFPFSENQICLTFTWKDAFDKGSLFGGSVKLALASLGYEKSCVLFNCAALASQIAAEQNLDNDEGLKTAAKQYQFASGAFLHIKDTVLSALSREPTVDISPDTVGTLSLIMLAQAQEVFFLKATRDKMKDAIIAKLANQAADYFGDAFKQCQYKDALPKYFYFQEVFPTLAAKQCIMQANAEYHQSILAKQQKKFGEEIARLQHAAELIKNVASRYDEYVNVKDFSDKINRALAAAKKDNDFIYHDRVPDLKDLDPIGKATLVKPTPVNVPISQKFTDLFEKMVPVSVQQSLAVFSQRKADLVNRSIAQ-MREATTLANGVLASLNLPAAIEDVSGDT-VPQSILTKSTAVVEQGGIQTVDQLIKELPELLQRNREILEESLRLLDEEEATDNDLRAKFKDR-WQRTPSNDLYKPLRAEGAKFRAVLDKAVQADGQVKERYQSHRDTIALLCKPEPELNAAIPSANPAKTMQGSEVVNVLKSLLSNLDEIKKEREGLENDLKSVNFDMTSKFLTALAQDGVINEEALSVTELDRIYGGLTTKVQESLKKQEGLLKNIQVSHQEFSKMKQSNSEASLREEVLKNLATAYDNFVELVANLKEGTKFYNELTEILVRFQNKCSDIVFARKTERDELLKDLQQSIAREPSAPSIPPPAYQS---SPAGGHATAP-TPAPRTMPPAKPQPPARPPPPVLPANRVPPAAAATAPAGVGTASAAPPQTPGSAPPPQAQGPPYPTYPGYPGYCQMPMPMGYNPYTYGQYNMPYPPVYHQSPGQAPYPGP--QQPTYPFPQPP--QQSYYPQQ-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8WUM4-1", "uniprot_id": "PDC6I_HUMAN", "id": "Q8WUM4-1", "name": "Programmed cell death 6-interacting protein", "aln": "MATFISVQLKKTSEVDLAKPLVKFIQQTY-PSGGEEQAQYCRAAEELSKLRRAAVGRPLDKHEGALETLLRYYDQICSIEPKFPFSENQICLTFTWKDAFDKGSLFGGSVKLALASLGYEKSCVLFNCAALASQIAAEQNLDNDEGLKIAAKHYQFASGAFLHIKETVLSALSREPTVDISPDTVGTLSLIMLAQAQEVFFLKATRDKMKDAIIAKLANQAADYFGDAFKQCQYKDTLPK-----EVFPVLAAKHCIMQANAEYHQSILAKQQKKFGEEIARLQHAAELIKTVASRYDEYVNVKDFSDKINRALAAAKKDNDFIYHDRVPDLKDLDPIGKATLVKSTPVNVPISQKFTDLFEKMVPVSVQQSLAAYNQRKADLVNRSIAQ-MREATTLANGVLASLNLPAAIEDVSGDT-VPQSILTKSRSVIEQGGIQTVDQLIKELPELLQRNREILDESLRLLDEEEATDNDLRAKFKER-WQRTPSNELYKPLRAEGTNFRTVLDKAVQADGQVKECYQSHRDTIVLLCKPEPELNAAIPSANPAKTMQGSEVVNVLKSLLSNLDEVKKEREGLENDLKSVNFDMTSKFLTALAQDGVINEEALSVTELDRVYGGLTTKVQESLKKQEGLLKNIQVSHQEFSKMKQSNNEANLREEVLKNLATAYDNFVELVANLKEGTKFYNELTEILVRFQNKCSDIVFARKTERDELLKDLQQSIAREPSAPSIPTPAYQS---SPAGGHAPTPPTPAPRTMPPTKPQPPARPPPPVLPANRAP-SATAPSPVGAGTAAPAPSQTPGSAPPPQAQGPPYPTYPGYPGYCQMPMPMGYNPYAYGQYNMPYPPVYHQSPGQAPYPGP--QQPSYPFPQPP--QQSYYPQQ-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B6D5-1", "uniprot_id": "A0A8M2B6D5_DANRE", "id": "A0A8M2B6D5-1", "name": "Programmed cell death 6-interacting protein", "aln": "MATFISVPLKKSSEVDLVKPLSKFVTATY-PPG-EEQAEYLRAVDELNKLRKSALGRPLDKHESSLEILLRYYDQLCAIEPKFPFP--ELCLTFTWKDAFDKGSLFGGSVKLALASLGYEKTCVLFNVGALASQIASEQNLDNDEGLKTAAKFYQLASGAFAHIKDTVLSALNREPTMDISPETVGTLSQIMLSQAQEVFVLKATSDKMKDAIVAKLANQAADYYGDAFKQCQYKENLPKYFYFQDVLPVLAAKHCMMQATAEMHQSALANQKKKFGEEIARLQHAQELVKTAASRYDEYVNVKDLSDKINRALTAAKKDNDFIYHDRVPEVKDLEHIGKASLVKATAVQTPLSQKFTDLFEKMVPMAVQQSVSAANSRKAETVNRLIGS-MREATNLCNGVLASLNLPAALEDLSGDA-VPQSILEKSRALIQQGGLQSIEQLIKDLPELLQRNREILDESLKMLDDEEATDNELRGKFNQR-WNRTPSGDLYKPLRAEGNNFRNILDKAVQADQVVRERYTAHCEMIALLCKPENELSAAIPSANPAKTLQGSEVVNVLRSQLAQLDEVKREREVLEGEVKSVTFDLTAKFLTALAQDGAINEEVMTSSELDARYGSHNQRVQQNLRRQEELLSQIQVSHQEFSALKQSNSEANTREDVLKKLASAHDSYIEISSNIKEGTKFYNDLTEILLKFQNKCSDIVFARKTERDELLKELQQSIAREPSAPSFSVPSYQSNTPAPAGGPTPAPRTVFSQQQPQAKPQPPARPPPPSIAPQAASAAVPVSAPMAPGSSNPPPVAPTG---PSQAQGPPYPSYQGYPGYYQMPM--AYNPYAYGQYNMPYMP--YQAQGQAGYPGAPATQQPYPYPQQPPQQQPYYPQQ-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VB05-1", "uniprot_id": "Q9VB05_DROME", "id": "Q9VB05-1", "name": "", "aln": "MSKFLGVPLKKPSEVDVIKPLNNLIQSTYNGASEEEKGKYGEAVNEFSKQRNTAIWKFFEKYEASLEIVYAYYDQICALETKISVS--ELQIPFKWKDAFDKGSIFGGKISLTHTSLLYEKVCVLFNIAALQSNIAANQSLDSDDGLKLTIKLLQQSAGIFQYLKGATPAAVPSEPTPDLSQDTLTVLQALMVAQAQEVFILKAIKDNLKDQIIAKLCCQAEESYADVLRAMQ-KESVRS-LWEKEWIPTIAGKQAGFHALTQLYQSLVCRAAKKIGEEIARLRNAIDLFKAAQTRSGNETYLDEYFSRAKRNLTESTKDNEFIYNEIIPELSTLTSPGKAQLAKPLPIAVPLAENFKDIFSSLVPVELHRALTASDMRRNEIVNVEIMK-LREATQTLNAVLASLNLPAAVETADGNSGLPPSLKEKANEVRQKGGIENVQTMLKDLPELLNRNREILDETERLLDEERDSDNQLRAQFKDR-WTRISSDKLTEMFRTNAKKYREVITNAIEADKVVRQKFEANQKGIQLLSLPPDQIQQSLPSASGSVDPNCS-SVQRLKKLMDDVETIKAEREAIESELKGATFNMKDEFLIALQKDGAIDEPALSLARIGQVLNPLQQQVRESVERQQSLVSEIQSAHGAF--VSETGSCGSSRDTLYQELATAFDSYIELSGNLQEGTKFYNDLTQLLVVFQNKISDFVFARKTEKEELLKDLTTESSRQACPATPALPSHYA---STSGSGSDIP-----------------------------PGSAPSVPPAASTANIPYPAQVQGMPIPYGAQ----PGVP-YPAYVPAPMPQSFNPYAT----LPYPG-NYQYQGFPQGPPP-GHYGTYPGSYAN--QQGGYPNQKPPGW", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12033-1", "uniprot_id": "PALA_YEAST", "id": "Q12033-1", "name": "pH-response regulator protein palA/RIM20", "aln": "MSELLAIPLKRTLEVDFATELSKLIDTTS----FQTASFFQSDILKVVDARNNAIAP--DISIDGLSALKEYYVILLQLEKKFPNN----QIEFTWFQTLSQK-----SRGTSQYSLQWEKLTIIYNIGCMYSLLALNSNNDAAESLKTSCLYFQNAAGCFKHVLDHQK---NLETIPVVDDATLNALTSLMLAQAQECFWFKAVQDKHKDSLIAKLSQQIVDFYCEAINDAQRGKLIRS-----DWINHLKAKKAYFSAVTYYRIALSFNEKKQFGNVVKALQMGLQFINESTLSS-----QAKFKTVVESSLKEAQRDNEFIYLQEVPSELPSIKPALMVKPSSSATLLPSIKKDETLFKDLIPIEVMEYCTAYNERQDEYVEQRVTNPLASLNKLLKESLTTFQIPQGLTKVSEAE------------------LSHYQASLNNLLINNKNVQVQLDNIEQILNEEAFTDNQLRLKHGTLNWTLPESSTTNTAYYEKLKKLRGYLDEGSAIDKQTNELFQS-------IDKNLIGSEIRLPESNDPLTNKIKMIIQERNDYIDRTRRKSSEYRILPKIITSYKKNGTVDFEPIFIG---------HLKYFDEDLRYVNSTKEENIKLIEEVNLSKKNNPGRSGIEPKKMVRIDPRELYIEDLRYSFKLLDEVKENLSAGTAFYENLITSTSNLYNEVQEYDTARRAEKARLDKSLTFEDQ-----------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: :: : **:. ***. . * ::: * : . : :. . *. *: : .*. : ** : :* *:. : *.* :::.: . : ** :** :::* ..: * :* :.. * :.** : * ::* * :: *. :. *: .* :*::**** * :** *: ** ::***. * : : :.:. * . : . : : : .*:. : * : : . *::*: : *: . ::.: . : * : :**:*** : :*. . .. . * :: :*..::*: : . :. . *: : *: : . : . . : *:::::* .: . :. : :::* :. : *:: ::*::* :**:** :. * *. : : * : :. * ..: : : : . :*.:. . : . :. .. : . * . : :.. . : . .* : :. .:.:. : : . : :. . *: :.* :.. *: *:. ** **::* : *: .: **::*: .* *.* . ", "identical_positions": 99, "similar_positions": 228, "identity": "11.12%" }, { "cls_id": "homologset.agr.MGI:1333754", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4KLH5-1", "uniprot_id": "AGFG1_RAT", "id": "Q4KLH5-1", "name": "Arf-GAP domain and FG repeat-containing protein 1", "aln": "MAASAKRKQEEKHLKMLRDMTG--LPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLNPPHRVKSISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKEFLQEKYEKKRWYVPPEQ-AKVVASVHASISGSSASSTSS------------TPEVKPLKSLLGESAPALHLNKGTPTQSPVVGRSQ--GQQQEKKQFDLLSDLGSDIFAAPAPQSTATANFANFAHFNSH-AAQNS-ANAEFANFDAFGQSSGSSNFGGFPTASHSPFQP---------------------------QTTGGSAGSVNANFAHFDNFPKSSSADFGSFSTSQSHQTASTVSKVSTNKAGLQTADKYAALANLDNIFSAGQG------------GDQGSGFGTTGKAPVGSVVSVPSHSSASSDKYAALAELDSVFSSAATSNNAYTSTSNASSSVFGTVPVGASPQTQPASS-GPAPFGATPSTNPFVAATGPSAASSTNPFQTNARGATA--------------------------------------ATFGTASMSMPAGFGTPAQYSLPTSFSGSFQQP--------------------PFPAQAAFPQQTAFSQQPNGAGFATFGQTKPVVTPFGQ-VAAAGVSSNPFMTGAPTGQFPTGSSSTNPFL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K2K6-4", "uniprot_id": "AGFG1_MOUSE", "id": "Q8K2K6-4", "name": "Arf-GAP domain and FG repeat-containing protein 1", "aln": "MAASAKRKQEEKHLKMLRDMTG--LPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLNPPHRVKSISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKEFLQEKYEKKRWYVPPEQ-AKVVASVHASISGSSASSTSS------------TPEVKPLKSLLGESAPALHLNKGTPSQSPVVGRSQ--GQQQEKKQFDLLSDLGSDIFAAPAPQSTATANFANFAHFNSH-AAQNS-ANADFANFDAFGQSSGSSNFGGFPTASHSSFQP---------------------------QTTGGSAGSVNANFAHFDNFPKSSSADFGTFSTSQSHQTASTVSKVSTNKAGLQTADKYAALANLDNIFSAGQG------------GDQGSGFGTTGKAPVGSVVSVPSHSSASSDKYAALAELDSVFSSAATSSNAYTPTSNASSSVFGTVPVGASAQTQPASS-GPAPFGATPSTNPFVAATGPSAASSTNPFQTNARGATA--------------------------------------ATFGTASMSMPAGFGTPAQYSLPTSFSGSFQQP--------------------AFPAQAAFPQQTAFSQQPNGAGFATFGQTKPVVTPFGQ-VAAAGVSSNPFMTGAPTGQLPTGSSSTNPFL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P52594-1", "uniprot_id": "AGFG1_HUMAN", "id": "P52594-1", "name": "Arf-GAP domain and FG repeat-containing protein 1", "aln": "MAASAKRKQEEKHLKMLRDMTG--LPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLNPPHRVKSISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKEFLQEKYEKKRWYVPPEQ-AKVVASVHASISGSSASSTSS------------TPEVKPLKSLLGDSAPTLHLNKGTPSQSPVVGRSQ--GQQQEKKQFDLLSDLGSDIFAAPAPQSTATANFANFAHFNSH-AAQNS-ANADFANFDAFGQSSGSSNFGGFPTASHSPFQP---------------------------QTTGGSAASVNANFAHFDNFPKSSSADFGTFNTSQSHQTASAVSKVSTNKAGLQTADKYAALANLDNIFSAGQG------------GDQGSGFGTTGKAPVGSVVSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTSTSNASSNVFGTVPVVASAQTQPASSSVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNARGATA--------------------------------------ATFGTASMSMPTGFGTPAPYSLPTSFSGSFQQP--------------------AFPAQAAFPQQTAFSQQPNGAGFAAFGQTKPVVTPFGQ-VAAAGVSSNPFMTGAPTGQFPTGSSSTNPFL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QBV1-1", "uniprot_id": "A0A8M9QBV1_DANRE", "id": "A0A8M9QBV1-1", "name": "", "aln": "MAASAKRKQEEKHLKMLREMTS--LAPNRKCFDCDQRGPTYANMTVGSFVCTSCSGILRGLNPPHRVKSISMTTFTQQEIELLQKHGNEVCKQIWLGLYDDRNLAIPDFREPQKVKEFLQDKYEKKRWYVPPEQ-AKTVASVHASISGSSASSTSS------------TPEVRPLKTLLGESVPSLHLNKNTPSQSPVVSRAQLAHQQYQDRKFDLLSDLGGDIFAPPHSQSTGNANFANFAHFNSH-SAQSVNASADFANFDTF-KSSAAPTTAAFPSAPQAPFQPP---QPVYNSLPFSRSVGEFTSLLPPLAMHSSSSGLSNANFANFDNFHKSCSADFPSFSSSQS----NSVGDVHKADAVSVPADRYAALADLDNIFSSKP--------------EQGP---SSAPPSAGVGPPPPQAALLGGDRYAAFAELDNVFGPSVPNVSGYQAATTAQGAVYGTSSAVPTAQAQQGLPNIPQGFAG-PSTNPFVAPGAP-QAPPTNPFQANGRAAVPGMG---------------VAAADMLGPLPGHSYPAAHFASFGPPSMSMPTGFGNTAAYNLPTSYSGNFQQ---------------------AFPGQP-FNQPHAYPQQPNG-GFAAFGQGK--VTPFGQNMVGQAVTNNPFLAGAPAAQFPAGGSTTNPFL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "B0UXL9-1", "uniprot_id": "B0UXL9_DANRE", "id": "B0UXL9-1", "name": "", "aln": "MAASAKRKQEEKHLKMLREMTS--LPPNRKCFDCDQRGPTYVNMTVGSFVCTTCSGILRGLNPPHRVKSISMTTFTQQEIEFLQKHSNELCKHIWLGLYDDKSSVIPDFREPQKVKEFLQEKYEKKRWYVPPEQ-AKVLASVQASISGSSASSTSS------------TPEVLP------QPLKTLHLTKTPSNQSPVISRAQ---SVGQEKKFDLLSDLGGDIFAAPQAQTAGSSNFANFAHFNRP-SAQNN-STTDFANFNSFGNASVSSHFGTSPPSKPSLQQP----------------------------HTGGG----------------------------------------------------------------------------------------MSVPPLPSMPPAPPLAGLSREDRYAALAELDSALSITIPAQGG-----------FGGVPGAPAPPPQHGLPNMQQGFAAAPSTNPFVAAGMVQEPMSTNPFQTNGRAAAS--------------------------------------ASFGTGSMSMPAGFGNTTSYCLPTSFSGTFQQ---------------------QFPGQGPFPPPAAYHQQPNG-GFPAYGQAKP-MGNYGQAVTGPGISSNPFMGGGPAGTYPTGGSSTNPFL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E1JHR0-1", "uniprot_id": "E1JHR0_DROME", "id": "E1JHR0-1", "name": "", "aln": "-MAVVRKKQDDKYLLALRELVASGTGSNRQCFDCGQKGPTYVNMTIGSFVCTRCSGVLRGLTPPHRVKSISMATFTQDEIDFLRSHGNELCAKTWLGLWDPKRAVHQ-----QEQRELMMDKYERKRYYLEPASPLKSLANAVNLKSSAPATNHTQNGHQNGYASIHLTPPAAQRTSANGLQKVANSSSNSSGKTSSSISRPHYNHQNNSQNNNHDAFGLGGGLSSLNSAGSTSTGALSDTSSCASNGFGADCDFVADFGSANIFDATSARSTGSPAVSSVSSVGSSNGYAKVQPIRAAHLQQQQQLQQQLHQQQLLNGNGHQGTENFADFDHAPIYNAVAPPTFNDWISDWSRRGFHDPFDDCDDSPPGARPPAPAPAPAQVPAVSSPLPTVREEPELAWNFWEDEMRIEAQEKESQTKQPELGYSFSISTTTPLSPSNPFLPYLVSEEQHRNHPEKPSFSYSLFSSISNSSQEDQADDHEMNVLNANFHDFFTWSAPLQNGHTTSPPKGGNAAMAPSEDRYAALKDLDEQLRELKASESATETPTPTSGNVQATDAFGGALNNNPNPFKGQQQQQLSSHVVNPFQQQQQQQHQQNLYGQLTLIPNAYGSSSQQQMGHHLLQQQQQQQQSFFNFNNNGFAISQGLPNGCGFGSMQPAPVMANNPFAASGAMNTNNPFL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .::**::*:* **::.. **:****.*:****.***:****** *** ****.**********:****:**::*:.*.**:* : ****:* : . *: :*:: :***:**:*: * . * :*.. *.:.*:. :. ** . : .: . . *. :.*.: . ...: . .**..: : . ::... ::: : . . ::*.. : * :* . . .: : .. ... * . :: . .. : :. . . . : . : *. . .*.* : . . .. :** . * * *.: . *** ..* : ** : .* :.: : . . . . : . . . . .:.****", "identical_positions": 102, "similar_positions": 147, "identity": "15.02%" }, { "cls_id": "homologset.agr.MGI:1333755", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B1ARL3-1", "uniprot_id": "B1ARL3_MOUSE", "id": "B1ARL3-1", "name": "Olfactory receptor", "aln": "--------------MARGNQTSTFEFLLWGLSEKPQQQHILFLVFLWMYLVTVAGNLLIVLAISTDVRLHTPMYFFLATLSCVDILFTSTTVPKALVNIHTQSRTISYAGCLVQLYFFLTFGDMDIFLLATMAYDRFVAICHPLHYRMIMSFQRCSLLVTACWTLTTVVAMTHTFLIFRLSFCSQKVIPDFFCDLGPLMKIACSETRINELVLLFLGGAVILIPFLLILMSYIRIVSAILRVPSAQGRRKAFSTCGSHLSVVALFFGTVIRAYLCPSSSSSNSVVEDTAAAVMYTVVTPLLNPFIYSLRNKDMKGALVRILKGKVSFSWAQGLLQRK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LX43-1", "uniprot_id": "A0ABK0LX43_RAT", "id": "A0ABK0LX43-1", "name": "Olfactory receptor", "aln": "--------------MARGNQTSTFEFLLWGLSEKPQQQHILFLLFLWMYLVTVAGNLLIVLAISTDVRLHTPMYFFLASLSCVDILFTSTTVPKALVNIHTQSRTISYAGCLVQLYFFLTFGDMDIFLLATMAYDRFVAICHPLHYTMIMSFQRCSLLVITCWTLTNLVAMTHTFLIFRLSFCSKKVIPDFFCDLGPLMKIACSETHINELVLLFLGGAVILIPFLLILVSYIRIVTAILRVPSAQGRHKAFSTCGSHLSVVALFFGTVIRAYLCPSSSSSNSVVEDTAAAVMYTVVTPLLNPFIYSLRNKDMKGALVRILKGKISFSWAQGLLQRR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NH06-1", "uniprot_id": "OR1P1_HUMAN", "id": "Q8NH06-1", "name": "Olfactory receptor 1P1", "aln": "MGLTQDFFPPTSELLEGGNQTSTFEFLLWGLSDQPQQQHIFFLLFLWMYVVTVAGNLLIVLAIGTDTHLHTPMYFFLASLSCADIFSTSTTVPKALVNIQTQSRSISYAGCLAQLYFFLTFGDMDIFLPATMAYDRYVAICHLLHYMMIMSLHRCAFLVTACWTLTSLLAMTRTFLIFRLSLCS-KILPGFFCDLGPLMKVSCSDAQVNELVLLFLGGAVILIPFMLILVSYIRIVSAILRAPSAQGRRKAFSTCDSHLVVVALFFGTVIRAYLCPSSSSSNSVKEDTAAAVMYTVVTPLLNPFIYSMRNKDMKAAVVRLLKGRVSFSQGQ------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q2PRL2-1", "uniprot_id": "Q2PRL2_DANRE", "id": "Q2PRL2-1", "name": "", "aln": "--------------MANETYMKNVDSFIITGFDHLQNQKLLGSLILISYMFILIGNIINLCIISTDRHLHKPMYILICNLAVVDIMYSSTCSTTMISVLLAEIKMVSYYSCITRTFFYHVADIAECMALTLMAIDRVVAIRLPLRYHSIVTNLRTFCFIFVTWLMGFAAVGFFTSVLDKSPYCQ-PLIKYAFCSYSSLVRAACVDPEPYFVISTIYSMVPLCGLFPFVMCTYAFLAYSVTKLSNS-SRKQMINTCLSHLIVLLSYYAPKVVTILLTRIGVVLTVTDRNAILIAASLVPPLINPTVYCTRTKEIRRRLSDFFLSTKILPNNFK-----", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . ...: :: :: *:*::: ::* *:. : **:: : *.** :**.***:::..*: .**: :** .. : : :: : :** .*:.: :*: . . : : : ** ** *** *:* *:: * :: . * : . * :: : . *. :: **. ..*:: :* :.. :: : . . : * ::: :* :. :: : ..: .*:: :.** *** *: ::.. : : * . . :* : .* : ::*.**:** :*. *.*::: : :: . :. ", "identical_positions": 61, "similar_positions": 129, "identity": "18.1%" }, { "cls_id": "homologset.agr.MGI:1333757", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O55106-1", "uniprot_id": "STRN_MOUSE", "id": "O55106-1", "name": "Striatin", "aln": "MDEQAGPGVFFSNNHPGAGGAKGLGPLAEAAAAGDGAAAAGAARAQYSLPGILHFLQHEWARFEVERAQWEVERAELQAQIAFLQGERKGQENLKKDLVRRIKMLEYALKQERAKYHKLKYGTELNQGDMKPPSYDSDEGNETEVQPQQNSQLMWKQGRQLLRQYLQEVGYTDTILDVKSKRVRALLGFSSDVTDREDDKNQDSVINGTEAEVKETAMIGKSELTDSASVLDNFKFLESAAADVSDEDEDEDTDGRAKSVIDTSTIVRKKALPDTSEDRDTKEALKEFDFLVTSEEGDNESRSAGDGTDWEKEDQCLTPEAWNVDQGVISKLKEQYKKERKGKKGVKRPNRSKLQDMLANLRDVDELPSLQPSVGSPSRPSSSRLPEQELSRADEVEALTFPPSSGKSFIMGADEALESELGLGELAGLTVANEADSLAYDIANNKDALRKTWNPKFTLRSHFDGIRALAFHPIEPVLITASEDHTLKMWNLQKTAPAKKSTSLDVEPIYTFRAHKGPVLCVVMSSNGEQCYSGGTDGRIQSWSTTNPNVDPYDAYDPSVLRGPLLGHTDAVWGLAYSAAHQRLLSCSADGTLRLWNTTEVAPALSVFNDNQELGIPASVDLVSSDPSHMVASFSKGYTSIFNMETQQRVLTLESNVDSTSSSSCQINRVISHPTLPISITAHEDRHIKFYDNNTGKLIHSMVAHLEAVTSLAVDPNGLYLMSGSHDCSIRLWNLESKTCIQEFTAHRKKFEESIHDVAFHPSKCYIASAGADALAKVFV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P70483-1", "uniprot_id": "STRN_RAT", "id": "P70483-1", "name": "Striatin", "aln": "MDEQAGPGVFFSNNHPGAGGAKGLGPLAEAAAAGDGAAAAGAARAQYSLPGILHFLQHEWARFEVERAQWEVERAELQAQIAFLQGERKGQENLKKDLVRRIKMLEYALKQERAKYHKLKYGTELNQGDMKPPSYDSDEGNETEVQPQQNSQFMWKQGRQLLRQYLQEVGYTDTILDVKSKRVRALLGFSSDVTDREDDKNQDSVINGTEAEVKETAMIGKSELTDSASVLDNFKFLENAAADFSDEDEDEDIDGREKSVIDTSTIVRKKPLPDTSEDRDTKEALKEFDFLVASEEGDNESRSAGDGTDWEKEDQCLTPERWNVDQGVITRLKEQYKKERKGKKGVKRPNRSKLQDMLANLRDVDELPSLQPSVGSPSRPSSSRLPEQDISRADEVEALTFPPSSGKSFIMGADEALESELGLGELAGLTVANEADSLAYDIANNKDALRKTWNPKFTLRSHFDGIRALAFHPIEPVLITASEDHTLKMWNLQKTAPAKKSTSLDVEPIYTFRAHKGPVLCVVMSSNGEQCYSGGTDGLIQSWSTTNPNVDPYDSYDPSVLRGPLLGHTDAVWGLAYSAAHQRLLSCSADGTLRLWTTTEVAPALTVFNDNQELGIPASVDLVSSDPSHMVASFSKGYTSIFNMETQQRILTLESNVDSTASSSCQINRVISHPTLPISITAHEDRHIKFYDNNTGKLIHSMVAHLEAVTSLAVDPNGLYLMSGSHDCSIRLWNLESKTCIQEFTAHRKKFEESIHDVAFHPSKCYIASAGADALAKVFV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O43815-1", "uniprot_id": "STRN_HUMAN", "id": "O43815-1", "name": "Striatin", "aln": "MDEQAGPGVFFSNNHPGAGGAKGLGPLAEAAAAGDGAAAAGAARAQYSLPGILHFLQHEWARFEVERAQWEVERAELQAQIAFLQGERKGQENLKKDLVRRIKMLEYALKQERAKYHKLKYGTELNQGDMKPPSYDSDEGNETEVQPQQNSQLMWKQGRQLLRQYLQEVGYTDTILDVKSKRVRALLGFSSDVTDREDDKNQDSVVNGTEAEVKETAMIAKSELTDSASVLDNFKFLESAAADFSDEDEDDDVDGREKSVIDTSTIVRKKALPDSGEDRDTKEALKEFDFLVTSEEGDNESRSAGDGTDWEKEDQCLMPEAWNVDQGVITKLKEQYKKERKGKKGVKRPNRSKLQDMLANLRDVDELPSLQPSVGSPSRPSSSRLPEHEINRADEVEALTFPPSSGKSFIMGADEALESELGLGELAGLTVANEADSLTYDIANNKDALRKTWNPKFTLRSHFDGIRALAFHPIEPVLITASEDHTLKMWNLQKTAPAKKSTSLDVEPIYTFRAHKGPVLCVVMSSNGEQCYSGGTDGLIQGWNTTNPNIDPYDSYDPSVLRGPLLGHTDAVWGLAYSAAHQRLLSCSADGTLRLWNTTEVAPALSVFNDTKELGIPASVDLVSSDPSHMVASFSKGYTSIFNMETQQRILTLESNVDTTANSSCQINRVISHPTLPISITAHEDRHIKFYDNNTGKLIHSMVAHLEAVTSLAVDPNGLYLMSGSHDCSIRLWNLESKTCIQEFTAHRKKFEESIHDVAFHPSKCYIASAGADALAKVFV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q05040-1", "uniprot_id": "FAR8_YEAST", "id": "Q05040-1", "name": "Factor arrest protein 8", "aln": "-----------------------------------MAINQAHVHPHYTLPGVMHYLQTEFTKNERDRITWELERSEMKARIAELEGENR------------------------------DLKHQLNQIQSKAVSPEGEKEEKHVPDSLLQSKLAVQENVKEIIYLLKGPNTVNQLESLNSREAGSELHDLEKLNVNTPKEEGSAKTNG-------------------------MDILNNALLDTKPNPKQGPSE--------SPSPTKVKSLFSTANKRENNETISKIHSELSKVDIISSYG------------DCMALYDADTKSLEIHQVDANLN--------------SKLLKKISLGQDSDIMKFFWVSTS-------------KLLVIEKSFHLKLFSISSASLISDVDLLQDSEQ---------PFSSSDIINIDFKN------------------------------KWLLIASKNKSQIRIWELDN-IEAPEDVPINIKETYEITHDN----------------------------------DDDDSNDSTNILDCILGITEKSLILLSSNPYQLTIYDFEG---KLLQKIDLKIDTILSGKPEEEGYHLFLDRKTS---KLLIQLSNERLLVYSFDKKK--VVLKEQLTPSSTLPIQLDLNDSIITVSYSNGDFEFRNLENLKPSIDEFVVADINFSERKEPVVFSSN---LIVDSTPVLITVN---------------KNNEVLLHKIKI--------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . .:.:*:***::*:** *::: * :* **:**:*::*:** *:**.: . :*** : *. * :.:: :: :. :*:: ::. : : *: . .: : .::*:.. : * ..:. . .:: .: ** :.:*:.* * . : :: : :.: .: *.* .:.:.*:.:*::.::. ::. : .. :*: :... * ::. : : *** . :: :* * : : *.. .: :: *.: . *. *:* ..* :** ..:* : *: * : :**::.:. :::*:*:: * :...:::: * : .: * *: *.: : . :** *: * * .:* : . :* . :: : .. :* * :* :* ::: .:*: ::.::.:: :.*:.:: .::. . *:: * *:. * .* *::: . . .::: : : . * .:....* *: .* * : *: * :*.: : ", "identical_positions": 94, "similar_positions": 236, "identity": "12.05%" }, { "cls_id": "homologset.agr.MGI:1333759", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0M6V8-1", "uniprot_id": "A0ABK0M6V8_RAT", "id": "A0ABK0M6V8-1", "name": "Vomeronasal type-1 receptor", "aln": "-------------------------MMNKNSRVHTDSNIR-NTFFTEIGIGILANSFLLLFHIFKFIRGQRSRLTDLPIGLLSLIHLLMLLMGAFIAI-DIFISWRG-WDDIICKFLVYLYRSFRGLSLCTTCMLSVLQAITLSPRS-SCLAKFKHKSPHHVSCAIISLSILYMFISSHLLVSINATPN-LTTNNFMQVTQSCYIIPLSYLMQSMFSTLLAIRDISLISLMVLSTCYMVVLLCRHRNQIQHLQGTNLSPKASPEQRATQTILMLMTFFVLMSIFDSIVSCSRTMYLNDPTSYYIQIFVVYIYATVSPFVFMSTEKHIVNFLKSMCVRVKNV-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5J3M4-1", "uniprot_id": "V1R94_RAT", "id": "Q5J3M4-1", "name": "Vomeronasal type-1 receptor 94", "aln": "----------MSEILLFSPQPLFSYTMNKYSRLYTNSNIR-NTFFSEIGIGIAANSLLLLFHIFKFIRGQRSRLTDLPIGLLSLIHLLKLLMIAFIAT-DIFISWRG-WDDIICKFLVYLYRSFRGLSLCTTCMLSVLQAITLSPRS-SCLAKFKHKSPHHVSCAILSLSVLYMFISSHLLVSLIATPN-LTTNVFMYVSESCSILPMSYLMQSMFSTLLAIRDVFLISLMVLSTCYMVALLCRHRKQTRHLQGTSLSPKASPEKKATHSILMLMSFFVLMSILDSIVSCSRTMFLYDPTSYAIQIFVSHIYATVSPFVFMSNEKHIVNFLRSLCKRVINV-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I5ZRA9-1", "uniprot_id": "A0A8I5ZRA9_RAT", "id": "A0A8I5ZRA9-1", "name": "Vomeronasal type-1 receptor", "aln": "-------------------------MMNKNSRLYTDSNIR-NTFFTEIGIGVSANSLLLLFNIFKLICGQRSRLTDLPIGLLSLINLLMLLMTAFIAT-DTFISWRG-WDDIICKSLLYLYRTFRGLSLCTSCLLSVLQAIILSPRS-SCLAKFKHKPSHHISCAILSLSVLYMFISSHLLVSIIATPN-LTTNDFIHVTQSCSILPMSYLMQSMFSTLLAIRDVFLISLMVLSTWYMVALLCRHRKQTRHLQGTSLSPKASPEQRATRSILMLMSLFVLMSVFDSIVCSSRTMYLNDPISYSIQLFMVHIYATVSPFVFIVTEKHIVNSLRSMCVKVMNV-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5J3K5-1", "uniprot_id": "VR102_RAT", "id": "Q5J3K5-1", "name": "Vomeronasal type-1 receptor 102", "aln": "MVGVQICQGMTSEILFFSLQPQFSNMMNKNSRLHIDSNIR-NTFFTEIGIGVSANSLLLLFNIFKFIHGQRSRLTDLPIGLLSLINLLMLLIMACIAT-DIFISCRR-WDDIICKSLLYLYRTFRGLSLSTTCLLSVLQAIILSPRS-SCLAKYKHKPPHHIFCAMLFLSVLYMFISSHLLLSIIATPN-LTTNDFIHVSQSCSILPMSYLMQSMFSTLLAIRNVFLISLIVLSTWYMVALLCRHRKQTRHLQDTSLSRKASPEQRATRSILMLRSLFVLMSIFDSIVSCSRTMYLNDPTSYSIQLLVVHIYATVSPFVFMITEKHIVNYLKSMYVRVLNV-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VIC6-1", "uniprot_id": "V1R51_MOUSE", "id": "Q8VIC6-1", "name": "Vomeronasal type-1 receptor 51", "aln": "----------MNEILFFSPQPLFSHMMNENSRVHTHSNLR-HIFFSEIGIGISGNSFLLLFHILKFIHGHRSRLSDLPIGLLSLIHLLMLLVMAFIAT-DIFISWRG-WDDIICKFLVYLYRVLRGLSLCTTSMLSVLQAIILSPRS-SCLAKFKRKSLHHISCAILFLSVLYMLIGSQLLVSIIATPN-LTTNDFIYVTQSCSILPLSYVMQSMFSTLLVIRDVFLISLMVLSTWYMVALLCRHRKKTQHLQGISLSPKTSPKQRATQTLLMLMSFFVLMTIYDTIVSCSRTMFLNDPTSYNMQIFVVHIYATVSPFVFMSTEKHIVNCLRSV------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TDU5-1", "uniprot_id": "VNRL4_HUMAN", "id": "Q8TDU5-1", "name": "Putative vomeronasal receptor-like protein 4", "aln": "---------------------------MEMTKLFSYIVIK-NVYYPQVSFGISANTFLLLFHIFTFAYTHRLKPIDMTISHLPLIHILLLFTQAILVSSDLFESWNIQNNDLKCKIITFLNRVMRGVSICTTCLLSVLQAITISPST-SFLEKFKHISANHTLGFILFSWVLNMFITNNLLLFIVPTPN-RIGASLLFVTEHCYVLPMSYTHRSLFFILMVLRDVIFIGLMVLSSGYG------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A5H1X0-1", "uniprot_id": "A5H1X0_DANRE", "id": "A5H1X0-1", "name": "Vomeronasal type-1 receptor", "aln": "--------------------------------MIAEAVIRGLLFLSLVLVGVPGNTAVICGFILLVRREGRLSPADAIVLHLCSANLVVVSVRCLLEVLATFRIHNV-FDDAGCRAVIFLHRTARSLSIWLTFLLTALQCLSVAPPG-SRRAAARALLARSLPAIFLALWLINTSMSVASLLYSIGARNDSRLLQNAINVEFCFLSFPSRLARDANGAAQVARDVVPMVLMAAGSLVLLVYLVRQRRRVQGLRGTAGGAAERRAAVTVVTLVSLYLLVFGLDNGLWVYTLTVSHTLSSALITDLRLFFTSLYTAVSPLLILVSNTRLRCGKQPETMH---------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0R4IM31-1", "uniprot_id": "ORA1_DANRE", "id": "A0A0R4IM31-1", "name": "Olfactory receptor class A-like protein 1", "aln": "--------------------------------MDLCVTIKGVSFLLQAGLGILANALVLLAYAHIRLAEARLQPVDAILCHLALVDLLLLLTRGVPQTMTVFGMRNL-LDDTGCKVVIYTYRIARALSVCITCMLSVFQAVTVAPAAGPLLSGVKARLPQLLAPTFAALWFINMAVCIAAPFFSVAPRN-GTVPPFTLNLGFCHVDFHDNLSYVLNGVAVSVRDFAFVGAMLASSGFILLLLHRHRRQVRAVRRSQGSTMETRAARTVLMLVILYSVFFGIDNVIWIYMLTVAQVPP--VVADMRVFFSSCYASLSPFLIISSNRKLKARMVCATSEQERQAEDGKNSSGKN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: : .*: .*: :: * * : * .:: : * . :* *: : : * *.:*: : :*:.:*.: ::* . : . : .: : . . * * : . *:. : : .: ", "identical_positions": 17, "similar_positions": 49, "identity": "4.83%" }, { "cls_id": "homologset.agr.MGI:1333760", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63302-1", "uniprot_id": "TFEC_RAT", "id": "Q63302-1", "name": "Transcription factor EC", "aln": "---------------------------------------------------------------------------------MTLDHRLFSQTLKRAQPLAASCM---PLAEHGPRSPDSDAGCAGNPFTNPLALGKEDGVVEWR-----------------------------LSGSILDVYSGEQGISPVNTGLMN---------ASCPSILPMKKEIAETDTRALAKERQKKDNHNLIERRRRYNINYRIKELGTLIPKSNDPDIRWNKGTILKASVDYIKWLQKEQQRARELEHRQKKLEHANRQLMLRIQELEIQARAHGLP-ILASLGTADFGTHITKQQTHSEKNSVGCCQQLTPSQGTSPEFYEQAVA-----------------------FSDPLSHFTDLSFSAALKEEQRLDGMLLSDTICPFGTDPLLSAISP-AVSKASSR-SSLSSEDGDEL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WTW4-1", "uniprot_id": "TFEC_MOUSE", "id": "Q9WTW4-1", "name": "Transcription factor EC", "aln": "---------------------------------------------------------------------------------MTFDCRVCDQTLKRAQPPAASCM---PLAEHEPMSPDSDAGCAGNPFTNLLALGKKDGAEKWH-----------------------------LSGSILDVYSDEQGISSANAGLTD---------APCPSILPMRKEIAETDGRALAKERQKKDNHNLIERRRRYNINYRIKELGTLIPKSNDPDMRWNKGTILKASVDYIKWLQKEQQRARELEHRQKKLEHANRQLRLRIQELEIQARAHGLP-ILASLGTADVGTHITKQQTHPERNLGGCCLQLTPTQGTSPEFYEQAVA-----------------------FSDPLSHFTDLSFSAALKEEQRLDGMLLSDTICPFGTDPLLSAISP-AVSKASSR-SSLSSEDGDEL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14948-1", "uniprot_id": "TFEC_HUMAN", "id": "O14948-1", "name": "Transcription factor EC", "aln": "---------------------------------------------------------------------------------MTLDHQIINPTLKWSQPAVPSGG---PLVQHAHTTLDSDAGLTENPLTKLLAIGKEDDNAQWHMEDVIEDIIGMESSFKEEGADSPLLMQRTLSGSILDVYSGEQGISPINMGLTS---------ASCPSSLPMKREITETDTRALAKERQKKDNHNLIERRRRYNINYRIKELGTLIPKSNDPDMRWNKGTILKASVEYIKWLQKEQQRARELEHRQKKLEQANRRLLLRIQELEIQARTHGLP-TLASLGTVDLGAHVTKQQSHPEQNSVDYCQQLTVSQGPSPELCDQAIA-----------------------FSDPLSYFTDLSFSAALKEEQRLDGMLLDDTISPFGTDPLLSATSP-AVSKESSRRSSFSSDDGDEL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58J6Y7-1", "uniprot_id": "A0AC58J6Y7_DANRE", "id": "A0AC58J6Y7-1", "name": "Transcription factor EC", "aln": "MFQSYYGVQAAPANIGNHQNQWAPEPQFSSCSYSYYSNQNPGPYQGSEPSAWPWTPFKVQSHLENSKYHLNQTQAQQVKQYLALGSKLASQAHPVAHPLPGQALGTVPVMRNGHMPPVSDSSTPGSPVTLLTLANNHDSEFP-------------------------------MDEVIDDLIGLENGFKDGSLDCMEPGIIMQNNVSLNSSMLEVYGADQEHDTRVLAKERQKKDNHNLIERRRRYNINYRIKELGTLIPKSNDPDMRWNKGTILKASVEYIKWLQKEQQHARDLESRQKKLEQANRRLQLRIQELEIQAHAHGLPSMTASMGTVELSSHLLKQQHHQTQATAASQSAQAPQSTQPPIYPQEGVSSPEYTQRTSLPSIVGEQSDGSNNFSDPLSHFTDFFCSTLKEEHQRLDEILMDDPLSPFGTDPLLSAGSPTAASKESSRRSSFSSEETDDL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :::. :: . : ::* . *: .: . **:. . .*.* .:.*. :. * *: . *:*:. . . . : .* * : * * *.****************************************:************:**********:**:** ******:***:* **********::**** **:**.:..:*: *** * : : . .* ::.:: ******:***: *: :*.**** :*:.*.:.********** ** *.** *** **:**:: *:*", "identical_positions": 157, "similar_positions": 78, "identity": "33.76%" }, { "cls_id": "homologset.agr.MGI:1333762", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0M6V8-1", "uniprot_id": "A0ABK0M6V8_RAT", "id": "A0ABK0M6V8-1", "name": "Vomeronasal type-1 receptor", "aln": "-------------------------MMNKNSRVHTDSNIR-NTFFTEIGIGILANSFLLLFHIFKFIRGQRSRLTDLPIGLLSLIHLLMLLMGAFIAI-DIFISW-RGWDDIICKFLVYLYRSFRGLSLCTTCMLSVLQAITLSPRS-SCLAKFKHKSPHHVSCAIISLSILYMFISSHLLVSINATPN-LTTNNFMQVTQSCYIIPLSYLMQSMFSTLLAIRDISLISLMVLSTCYMVVLLCRHRNQIQHLQGTNLSPKASPEQRATQTILMLMTFFVLMSIFDSIVSCSRTMYLNDPTSYYIQIFVVYIYATVSPFVFMSTEKHIVNFLKSMCVRVKNV-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5J3M4-1", "uniprot_id": "V1R94_RAT", "id": "Q5J3M4-1", "name": "Vomeronasal type-1 receptor 94", "aln": "----------MSEILLFSPQPLFSYTMNKYSRLYTNSNIR-NTFFSEIGIGIAANSLLLLFHIFKFIRGQRSRLTDLPIGLLSLIHLLKLLMIAFIAT-DIFISW-RGWDDIICKFLVYLYRSFRGLSLCTTCMLSVLQAITLSPRS-SCLAKFKHKSPHHVSCAILSLSVLYMFISSHLLVSLIATPN-LTTNVFMYVSESCSILPMSYLMQSMFSTLLAIRDVFLISLMVLSTCYMVALLCRHRKQTRHLQGTSLSPKASPEKKATHSILMLMSFFVLMSILDSIVSCSRTMFLYDPTSYAIQIFVSHIYATVSPFVFMSNEKHIVNFLRSLCKRVINV-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I5ZRA9-1", "uniprot_id": "A0A8I5ZRA9_RAT", "id": "A0A8I5ZRA9-1", "name": "Vomeronasal type-1 receptor", "aln": "-------------------------MMNKNSRLYTDSNIR-NTFFTEIGIGVSANSLLLLFNIFKLICGQRSRLTDLPIGLLSLINLLMLLMTAFIAT-DTFISW-RGWDDIICKSLLYLYRTFRGLSLCTSCLLSVLQAIILSPRS-SCLAKFKHKPSHHISCAILSLSVLYMFISSHLLVSIIATPN-LTTNDFIHVTQSCSILPMSYLMQSMFSTLLAIRDVFLISLMVLSTWYMVALLCRHRKQTRHLQGTSLSPKASPEQRATRSILMLMSLFVLMSVFDSIVCSSRTMYLNDPISYSIQLFMVHIYATVSPFVFIVTEKHIVNSLRSMCVKVMNV-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5J3K5-1", "uniprot_id": "VR102_RAT", "id": "Q5J3K5-1", "name": "Vomeronasal type-1 receptor 102", "aln": "MVGVQICQGMTSEILFFSLQPQFSNMMNKNSRLHIDSNIR-NTFFTEIGIGVSANSLLLLFNIFKFIHGQRSRLTDLPIGLLSLINLLMLLIMACIAT-DIFISC-RRWDDIICKSLLYLYRTFRGLSLSTTCLLSVLQAIILSPRS-SCLAKYKHKPPHHIFCAMLFLSVLYMFISSHLLLSIIATPN-LTTNDFIHVSQSCSILPMSYLMQSMFSTLLAIRNVFLISLIVLSTWYMVALLCRHRKQTRHLQDTSLSRKASPEQRATRSILMLRSLFVLMSIFDSIVSCSRTMYLNDPTSYSIQLLVVHIYATVSPFVFMITEKHIVNYLKSMYVRVLNV-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VIC7-1", "uniprot_id": "V1R45_MOUSE", "id": "Q8VIC7-1", "name": "Vomeronasal type-1 receptor 45", "aln": "----------MSEILFFSPQPLFSHMMNKNSRLHTHSNIK-NTFFSEIGIGILGNSFLLLFHILKFIRGHRLRLTDLPIGLLSLIHLLMLLLMAFIAT-DIFISR-RGWDDIICKFLVYLYRVLRGLSLCTTSMLSVLQAIILSPRS-SCLAKLKHKYPHHISCAIIFLSVLYMLISSHILLSIIATPN-LTRNDFLYVTQSCSILPLSYVMQSMYSTLLALREVFLISLMVLSTLYMVVLLCRHRKQAQHLQGTSLSPKASAEQRATQTILMLMTFFVLMSIFDSIVSCSRTMFLDDPTSYSIHIFVMHIYATVSPFVFMSTEKHIVNILRG-------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TDU5-1", "uniprot_id": "VNRL4_HUMAN", "id": "Q8TDU5-1", "name": "Putative vomeronasal receptor-like protein 4", "aln": "---------------------------MEMTKLFSYIVIK-NVYYPQVSFGISANTFLLLFHIFTFAYTHRLKPIDMTISHLPLIHILLLFTQAILVSSDLFESWNIQNNDLKCKIITFLNRVMRGVSICTTCLLSVLQAITISPST-SFLEKFKHISANHTLGFILFSWVLNMFITNNLLLFIVPTPN-RIGASLLFVTEHCYVLPMSYTHRSLFFILMVLRDVIFIGLMVLSSGYG------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A5H1X0-1", "uniprot_id": "A5H1X0_DANRE", "id": "A5H1X0-1", "name": "Vomeronasal type-1 receptor", "aln": "--------------------------------MIAEAVIRGLLFLSLVLVGVPGNTAVICGFILLVRREGRLSPADAIVLHLCSANLVVVSVRCLLEVLATFRIH-NVFDDAGCRAVIFLHRTARSLSIWLTFLLTALQCLSVAPPG-SRRAAARALLARSLPAIFLALWLINTSMSVASLLYSIGARNDSRLLQNAINVEFCFLSFPSRLARDANGAAQVARDVVPMVLMAAGSLVLLVYLVRQRRRVQGLRGTAGGAAERRAAVTVVTLVSLYLLVFGLDNGLWVYTLTVSHTLSSALITDLRLFFTSLYTAVSPLLILVSNTRLRCGKQPETMH---------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0R4IM31-1", "uniprot_id": "ORA1_DANRE", "id": "A0A0R4IM31-1", "name": "Olfactory receptor class A-like protein 1", "aln": "--------------------------------MDLCVTIKGVSFLLQAGLGILANALVLLAYAHIRLAEARLQPVDAILCHLALVDLLLLLTRGVPQTMTVFGMR-NLLDDTGCKVVIYTYRIARALSVCITCMLSVFQAVTVAPAAGPLLSGVKARLPQLLAPTFAALWFINMAVCIAAPFFSVAPRN-GTVPPFTLNLGFCHVDFHDNLSYVLNGVAVSVRDFAFVGAMLASSGFILLLLHRHRRQVRAVRRSQGSTMETRAARTVLMLVILYSVFFGIDNVIWIYMLTVAQVPP--VVADMRVFFSSCYASLSPFLIISSNRKLKARMVCATSEQERQAEDGKNSSGKN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *: : .*: .*: :: * * : * .:: : * :* *: : : * *.:*: : :*:.:*.: ::* . : .. : .: : . . * * : . *:. : : .: ", "identical_positions": 18, "similar_positions": 48, "identity": "5.11%" }, { "cls_id": "homologset.agr.MGI:1333763", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q80VP1-1", "uniprot_id": "EPN1_MOUSE", "id": "Q80VP1-1", "name": "Epsin-1", "aln": "---------MSTSSLRRQMKNIVHNYSEAEIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMIWKRLNDHGKNWRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQGVNVREKAKQLVALLRDEDRLREERAHALKTKEKLAQTATASSA----------AVGSG-------PPPEAEQAWPQSSGEEELQLQLALAMSKEEADQP-PSCG-----PEDDVQLQLALSLSREEHD-----------KEERIRRGDDLRLQMAIEESKRETGGKEESSLMDL--ADVFTTPA-------------PPQASDPWGGPAS--VPTAVPVAAA-----ASDPWGGPAVPPAADPWGGAAPTPASG-----DPWRP-----------AAPTGPSVDPW-----------GGTPAPAAGEGP-TPDPWGSSDGGAPVSGPPSS---DPWAP-------APAFSDPWGGS------------------PAKPSSNG-TAVGGFDTEPDEFSDFDRLRT------------------ALPT---------SGSSTGELELLAGEVP-ARSPG--------------------AFDMSGVG--------GSLAESVGSPPPAATP----TPTPPTR-----KTPESFLGPNAALVDLDSLVSRPGP-------TPPGS-KASNPFLPSGAP-PTGPSVTNPFQPAPPATLTLNQLR----------------------LSPVPP-----------------VPGAP-------PTYISPLGGGPGLPP-------------MMPPG-------------------PPAPNTNPFLL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O88339-1", "uniprot_id": "EPN1_RAT", "id": "O88339-1", "name": "Epsin-1", "aln": "---------MSTSSLRRQMKNIVHNYSEAEIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMIWKRLNDHGKNWRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQGVNVREKAKQLVALLRDEDRLREERAHALKTKEKLAQTATASSA----------AVGSG-------PPPEAEQAWPQSSGEEELQLQLALAMSKEEADQP-PSCG-----PEDDVQLQLALSLSREEHD-----------KEERIRRGDDLRLQMAIEESKRETGGKEESSLMDL--ADVFTTPA-------------PPQASDPWGGPAS--VPTAVPVAAA-----ASDPWGAPAVPPAADPWGGAAPTPASG-----DPWRP-----------AAPTGPSVDPW-----------GGTPAPAAGEGP-TSDPWGSADGGAPVSGPPSS---DPWAP-------APAFSDPWGGS------------------PAKPSSNG-TAVGGFDTEPDEFSDFDRLRT------------------ALPT---------SGSSTGELELLAGEVP-ARSPG--------------------AFDMSGVG--------GSLAESVGSPPPAATP----TPTPPTR-----KTPESFLGPNAALVDLDSLVSRPGP-------TPPGA-KASNPFLPSGAP-ATGPSVTNPFQPAPPATLTLNQLR----------------------LSPVPP-----------------VPGAP-------PTYISPLGGGPGLPP-------------MMPPG-------------------PPAPNTNPFLL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y6I3-2", "uniprot_id": "EPN1_HUMAN", "id": "Q9Y6I3-2", "name": "Epsin-1", "aln": "---------MSTSSLRRQMKNIVHNYSEAEIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMIWKRLNDHGKNWRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQGVNVREKAKQLVALLRDEDRLREERAHALKTKEKLAQTATASSA----------AVGSG-------PPPEAEQAWPQSSGEEELQLQLALAMSKEEADQP-PSCG-----PEDDAQLQLALSLSREEHD-----------KEERIRRGDDLRLQMAIEESKRETGGKEESSLMDL--ADVFTAPA-------------PAPTTDPWGGPAP--MAAAVPTAAP-----TSDPWGGPPVPPAADPWGGPAPTPASG-----DPWRP-----------AAPAGPSVDPW-----------GGTPAPAAGEGP-TPDPWGSSDGGVPVSGPSAS---DPWTP-------APAFSDPWGGS------------------PAKPSTNGTTAAGGFDTEPDEFSDFDRLRT------------------ALPT---------SGSSAGELELLAGEVP-ARSPG--------------------AFDMSGVR--------GSLAEAVGSPPPAATP----TPTPPTR-----KTPESFLGPNAALVDLDSLVSRPGP-------TPPGA-KASNPFLPGGGP-ATGPSVTNPFQPAPPATLTLNQLR----------------------LSPVPP-----------------VPGAP-------PTYISPLGGGPGLPP-------------MMPPG-------------------PPAPNTNPFLL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IUB6-1", "uniprot_id": "A0A0R4IUB6_DANRE", "id": "A0A0R4IUB6-1", "name": "", "aln": "---------MSTSSLRRQVKNIVHNYSEAEIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMVWKRLNDHGKNWRHVYKAMTLMEYLIKTGSERVAQQCRENIYAVQTLKDFQYIDRDGKDQGVNVREKAKQLVTLLKDEERLREERIHALKTKEKMAQTSSASSAP------SAPALGGGGV----HSGADSDQAWPQSSGEEDLQLQLALAMSKEEAEQKRPCCDKTTHDPLEDAEIRYALTISQETHQ-----------QEERLRRGDDLRLQMAIEESKREKTKPEESSLMELSAADPWGAPATGSAGPSPPPALGPASTAGPWGPPDP--WGATSPASPP-----SADPWAGAPATVAPDPWSDSS-SRVNS-----DPWAS-----------TAVTPPSADPW-----------AHSVAPAPTPLSGSTDPW-AAEGAAPATDGLTS---DPWSG-------SVKQTNGTADP------------------ERRGSSVTCDAGGGGSTGSPVPFDLSSLGS------------------SLPVRKTPESFLGPNAALVDLDSLVSSKPKPKQPP--------------------PPSISSTSNNPFLQTQGPSSTGMGVTPGSTISSRGVSPTPPSASNPFGATPMASISPQPSSLGLNQLRTSPVP-------PNPMLGHMPPPVVGMVQP-GMGMPGMGVPMAAPGLSMGMGMPYGG--------------------ISPMGPGGNPLLM----------GPGGP-------AQPSLILGGPSGVGG-------------VMGTGGSMGGG-------------TTGTSTNPFLL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VS85-1", "uniprot_id": "Q9VS85_DROME", "id": "Q9VS85-1", "name": "", "aln": "MRKQKDDMQVNVAGLRRNIKNLAHNYSDAQVKVREATSNDPWGPSAAIMSEIAELTYNVVAFSEIMQMIWKRLNDHGKNWRHVYKALILLEYLIKTGSEKVAQQCKENIFAIQTLREFVYFE-EGKDQGTHVREKAKQLVTLLKDDERLKNERVKAQKAKERFAQNPSGFGSDGYIDGPSQRDLPPGWQEEPPKSVSELEMVRPQTAGEEELQLQLAMAMSREEAEQEEAKRR------SDDVRLQLALSQSEQDFKDPNGRPIPAPKKEEQQSHLLDL-LDISLGATSISSPPLGAAGGAPTAVVDPWAMPGPR----------APSQLSDPWSGTSSPQVDPWNPSAAPRTILGAGVPMTSAPLGAGNDAWGARTQSPSVASGSSNEGWLQSNGNANQNGRGATPAGPPAEGWLIKSTAVGALGAAPINHAANNGSSSSDPWLAEPAASAAGGAAAVGLADPWAPGAASQTGAGALDDPWKALGTGAIKKQSPEFDEFDLITNRNKSEHSNSNASNNNNASLLDDMDPLSANYGNGGINSSMHPSTGATAKKSIKDAHSFLGENSALVNLDNLIKPIAPQTQTGNQPAYNPFSDNVVPPKTNLFQQQQPAVPSINQLKQQAPFSVSMNQDPWAPVMGGVSTTSQPKLPPPVRPTSLNLGPSSVGEFQLLSALSNPIIPIAHIPQPQPNLQVYNNAYQSSSSTNILGKSNIPTNMNSSTSNSTIHSCYASPSPGVDGIRNMDIFTERPYYNSPTAPADDTYMYNSRDNNNINSNYGTPSLYSSFAASYSSALSDSLAETPGISVAPLGFVADTVMSFGPSSSSANCKLEQNNNMPWIKPEAATNPFLS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12518-1", "uniprot_id": "ENT1_YEAST", "id": "Q12518-1", "name": "Epsin-1", "aln": "----------MSKQFVRSAKNLVKGYSSTQVLVRNATSNDNHQVSKDSLIELAEKSYDSADFFEIMDMLDKRLNDKGKYWRHIAKALTVIDYLIRFGSENCVLWCRENLYIIKTLKEFRHEDDEGIDQGQIVRVKAKELTALLSDDERLNEE--RNMNIKGR--NRKGRRR------------------------RGTGRSDEND------DDLQRAISASRLTAEEDERRRK-------QDEDYETALQLSKEEEE------------LKRLQDLQRMQQQQG------------QQQLQQPMYYDIFGNPITPEE-----YAQFQLQQQQ------------QQQQQQLQQQPMYYDVFGNPITPEELAQFQQQQQLQEQQ---YLASMQQ------------QQQAMSNNPFAKS--------------EQSSSSPKRNQLVAASSPQ-------------------------QLQQQ------------------------KQQEPLIQNRTGNQSMTDKYSKLNELLA-------------------------------TGTGIDTFGNVGEARIPAQHTK-----------------------------------TGTFINSQGTGYRQVSDD---PNHNPFLNSQYTGLPSTSVVPTQTGYGFGNQSQ---------------------------------------------------------------------------------------------------------------QQSQNNGSNNRGYT-------------------------------------------LIDL--", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q05785-1", "uniprot_id": "ENT2_YEAST", "id": "Q05785-1", "name": "Epsin-2", "aln": "----------MSKQFVRSAKNMMKGYSSTQVLVRDATANDSRTPSIDTLDDLAQRSYDSVDFFEIMDMLDKRLNDKGKYWRHVAKSLTVLDYLVRFGSENCVLWCRENFYVIKTLREFRHENESGFDEGQIIRVKAKELVSLLNDEERLREE--RSMNTRNRRANRAARPRPR----------------------RQRTRSNPHDSSPSYQDDLEKALEESRITAQEDEQRRRELAQYDDEDPDFQAALQLSKEEEE------------LKQLQELQRLQKQQQS-LSQFQAPLQQQQPQQQPAYYDIFGNPISQDE-----YLQYQYQQDQEQAMAQQRWLDQQQEQQQLAEQQYFQQQQQAAAAASALQQQQTAANMQQQQQ--QPADFQQ------------PLPTGSNNPFSMDN-------LERQKQEQQHAQLQRQQEEARQQQEQLKLQQLQRQQQEEAQLHQKRQEEAQLQQQQAQLLQ-------------QQAQFQQQQPLKQTRTGNQSISDKYSDLNTLLA-------------------------------TGTGIDTFGNTGEARIPAQHTK-----------------------------------TGTFINSQGTGYKQVTNE---PKNNPFLSNQYTGLPSTNIVPTQTGYGFGNQPQSPPTNSPQQNPTGISYSQPQQQQQPQQQPQYMQNFQQQQPQYAQNFQQQPQYTQNY------------------------------------------QQQPQYIQPHQQQQQQQQQQQQQQGYTP-------------------------------------DQGVSLIDL--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *. **: :.**.::: **:**:** * : ::*: :*: . * ***.*: *****:** ***: *:: :::**:: ***. *:**:: ::**::* : : .* *:* :* ***:*.:** *::**.:* : : : : : : :*: *: *: *:: :* . ** *.: . :: : : * : * . . : : : : : : . . .. . .:. * : .:. : . .. . . . * . . : . . : ", "identical_positions": 67, "similar_positions": 104, "identity": "7.89%" }, { "cls_id": "homologset.agr.MGI:1333764", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LIU6-1", "uniprot_id": "A0ABK0LIU6_RAT", "id": "A0ABK0LIU6-1", "name": "Olfactory receptor", "aln": "MENSTTIVTEFILLGLSDACELQVIIFLGFLLTYFLILLGNFLIIFITLADRRLYTPMYYFLRNFAVLEIWFTSVIFPKMLTNIVTGHKTISLLGCFLQTFFYFFLGTTEFFLLAVMSFDRYVAICNPLRYGTIMSKRVCVQLVFCSWTAGFLLIMVPSSILFQQPFCGHNIINHFFCDNFPLMELICADTSLVEILGFIIANFSLLGTLAVTATCYGHILYTILHIPSAKERKKAFSTCSSHIIVVSLFYGSCIFMYVRSGKNGQGEDHNKVVALLNTVVTPTLNPFIYTLRNKQVKQVFREHISKILKLNPT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z1V0-1", "uniprot_id": "OR6E1_MOUSE", "id": "Q9Z1V0-1", "name": "Olfactory receptor 6E1", "aln": "MANSTT-VTEFILLGLSDACELQVLIFLGFLLTYFLILLGNFLIIFITLVDRRLYTPMYYFLRNFAMLEIWFTSVIFPKMLTNIITGHKTISLLGCFLQAFLYFFLGTTEFFLLAVMSFDRYVAICNPLRYATIMSKRVCVQLVFCSWMSGLLLIIVPSSIVFQQPFCGPNIINHFFCDNFPLMELICADTSLVEFLGFVIANFSLLGTLAVTATCYGHILYTILHIPSAKERKKAFSTCSSHIIVVSLFYGSCIFMYVRSGKNGQGEDHNKVVALLNTVVTPTLNPFIYTLRNKQVKQVFREHVSKFQKFSQT", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* **** *****************:************************.****************:*****************:**************:*:*****************************.**************** :*:***:*****:******* *************************:***:********************************************************************************************************:**: *:. *", "identical_positions": 291, "similar_positions": 17, "identity": "92.68%" }, { "cls_id": "homologset.agr.MGI:1333765", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q2PRE9-1", "uniprot_id": "Q2PRE9_DANRE", "id": "Q2PRE9-1", "name": "Olfactory receptor", "aln": "-MDNSTYFTTVILTGYIDIG-DIKYLCFVVLILLFAAIIVANLFIIGIICKEKSLHEPMYVFLCSLCANQLCGSFALFPFVLGNMLRSKTP-EVPLTVCHAQIFALYTYGQVEFCNLAMMSYDRYVAICHPLEYHRIMSPARTMTLIALGWSLQIIIFSLSFSVNVQLKLCG-NVLDKVWCDQYMLVKLACSDTTPNNIAGMTGIAVTIGAPLLLILFSYAKILRVCLKFKGQ-TAQKSLYTCILHLISLLNFAVGCSFELIQSRFGKLPMPAVVRVILSLYFLVCPPLFNPIMYGVRLANIKKALKKMICM-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0ACD6B7K1-1", "uniprot_id": "A0ACD6B7K1_DANRE", "id": "A0ACD6B7K1-1", "name": "Olfactory receptor", "aln": "-MENGANFTFIRLTGYLNLDFKMKYFLFAVLTVLYLTIICANSFLIGVICLAKILHKPMYMFLCSLFVNELYGSTALFPSLQVNLLLNDN--TISLVYCYLQIFCLCTYAMIDFCTLAVMSFDRYVSICYPLQYNKIMTPFRVGLLIALVWTYCFIQFFIFLSFKFKLQLCG-NVMEKVWCDNYLLVNLACSKSSLHNAYGIYLAVVTAVIPLTLIFYSYTRIIKICLSFSKE-AKKKALSTCTPHIISLLNFTLGCFFETLQSRFDEIRTPALIRVIVSLYLLMCQPLLNPILYAIRLKNIRLVCKNLVLSKIGIA--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q2PRG1-1", "uniprot_id": "Q2PRG1_DANRE", "id": "Q2PRG1-1", "name": "", "aln": "-MENYTSFNFMLFEN---LG-YIRYSLFVLGFVLYFAIIFFNVLIMLAVFLERTLHQPMYILISCLSMNSLFGTAGFFPRVLSDLLSETH--SISREACFSQSFVIFTYVANEFSILMLMAFDRFAAICKPLRYHSIVRPRFLACLIVINLNCIMILLCVAALLTTKLRMCG-NKLFKVYCHSYEVLKLSCDNILINNAFGLLLVIITTIIPLGLILLSYVKILIICQRSSAQ-FKGKAYQTCIPHIVILLNFTIAVTCDTTLSRVVNLQIPVGLSVFLSLEFLIIPPVLNPLIYAFNLPDIRKKMISLIKPLK-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q2PRA7-1", "uniprot_id": "Q2PRA7_DANRE", "id": "Q2PRA7-1", "name": "", "aln": "-MDNNSSFSMFSLTALNGSR-SSRITIFSFALPGYFLTIFVNTLLILIIVLEKVLHQPMYIFLCNLCINGLYGATGFYPPLLYYLLSESN--VISLKECAIQSFAIFTYAIGEFTNLSVMAFDRYLAICRPLYYHNIMTTVTVWRLLTFIWMFPCCTAILLILMTLRFPICI-KKISKLYCETWVLERLVCGVDTAQFVFNG-ILTCAVNALVWFVFLSYINILVAC-KHSVQ-NHKKFISTCLPHLIAFLNYVFWSLFSTLYELFGISSLSQEFKNFLSVTFMIIPPLINPVIYGIVLTPIRTKAKHVFQSFRPKHID", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8VGN4-1", "uniprot_id": "Q8VGN4_MOUSE", "id": "Q8VGN4-1", "name": "Olfactory receptor", "aln": "-MNNITEFILVGLTQNMELQ----IFSFVVFFIVYLLTLAGNLLIMVTISSSKALGSPMYFFLSFLSLIDGCCSSSMTPKMLADSLSVRK--TISFSGCMTQVFAEHFFGAAEIILLTVMAYDRYVAICKPLRYTIIMNRFVCGLLVGVAWAGGFIHATIQILFTVWLPFCGPNVIDHFMCDLTPLLKLVCMDTHNLGLFVAANSGFICLLNFLLLMISYIVILDALKSHSKE-GRCKALSTCVSHITVVILFFVPCIFVYLRP-----VITFSIDKAVAVFYTMITPMLNPLIYTLRNTEVKNAMKKLCIKVD-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3Z928-1", "uniprot_id": "D3Z928_RAT", "id": "D3Z928-1", "name": "Olfactory receptor", "aln": "-MNNITEFILVGLTQNMELQ----IFSFVVFFIVYLLTLAGNLLIMVTISSSRALGSPMYFFLSFLSLIDGCCSSSMTPKMLVDSLSAKK--TISFTGCMTQVFAEHFFGAAEIILLTVMAYDRYVAICKPLRYTIIMNRFVCGLLVGVAWAGGFVHATIQILFTVWLPFCGPNVIDHFMCDLTPLLKLVCMDTRNLGLFVAANSGFICLLNFLLLMISYVVILDALKSHSKE-GRRKALSTCVSHITVVILFFVPCIFVYLRP-----VMTFSIDKAVAVFYTMITPMLNPLIYTLRNTEVKNAMKKLCVQVDLN---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q2PRI1-1", "uniprot_id": "Q2PRI1_DANRE", "id": "Q2PRI1-1", "name": "", "aln": "-MDNLTFRHSVLLVEGLKVTHQSSQPVFIVLFLSYIFAMISNITLIFLISTEKNLHDPMHFLFCNLPVNDIIGTTVILPRLMQDVLKEASERYISYTECVVQAYFVHVFTAACHYVLMIMAFDRYVAICNPLRYTAIMTNKMVIKLSASAWGLAIIVVTVMIGLTLRLSHCR-STIENPFCDNASLFKLSCENVSINNAFGVVYSVIVACLSAISIFITYVKIATVCLASKNKALNSKAMKTCSTHLAVYLIMFVSGAIFIFLHRFP--EYAE-SRKLGSIMFHIVPPGLNPLVYGLQTKEIRQRFVKLCRRKTSTSLM", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q2PRH9-1", "uniprot_id": "Q2PRH9_DANRE", "id": "Q2PRH9-1", "name": "", "aln": "-MDNLTFTNSILLVEGLKVTPQSSQPVFIMFLLAYIFAMVSNIGLIFLISTEKNLHDPMHFLFCNLPLNDIMGTTVIMPRLLQDILTEASERYISYAECAIQAYFVHVFTAACHYVLMIMAFDRYVAICNPLRYTAIMTNKMVIGLSALAWGLAIIFVTIMVGLSLRLSRCR-YKIENPFCDNASLFKLSCENVSVNNVFGLVYTVIVLSLSALSIFVTYVKIATVCVTSKNKALNSKAIKTCSTHLAVYLIMFVTGAVFIFLHRFP--EYSD-NRKLASIMFHIVPPGLNPLVYGLQTKEIRQKVVKLWCRKKSMIT-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q2PRH7-1", "uniprot_id": "Q2PRH7_DANRE", "id": "Q2PRH7-1", "name": "", "aln": "-MDNLTFTNDFLLVEGLKVTYPSSYPIFILLFLFYIFAMGCNIGLIILIATEKKLHHPMHFLFCNLPVNDIIGTTVILPRLICDIFKQTSERSMTYVECVVQAYFVHIFTTASHTALVTMAYDRQVAICNPLLYTAVMTDKMVVKLSATAWTLPIIVVAVMIGLTVRLSRCR-SKIENPFCDNASLYKLSCENVAINNIFGIVYSVAALIISVALMVIAYARIVTACIISKSKALNSKAIKTCSSHIAVYLIMFVSCAIMIFFHRFP--EYSE-NRKLASIMFHIVPPGLNPIVYGLQTKEIRQIIVKRWWKNAVDKL-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q32PT6-1", "uniprot_id": "Q32PT6_DANRE", "id": "Q32PT6-1", "name": "", "aln": "-MDNRTFRYSTLLVEGLQITQQSSQLTFIFLLTVYVFSMVSNIGILIQILAEKSLHQPMYILFCHLPMSDIIGATVLIPRLLKDLLTDPSERYITYIECVLQAFFTHLYGTTSHTILMIMAFDRYVAICNPLRYPTIMNNKMIVKLSAGAWGAAIVLVGILIGLSVRLSHCR-SVIENHVCDNPSLFKLSCENTFINNVYGLTFTVVLLTSSLGWVVLTYLRIAMVCIKSKHKATNSKAIKTCTTHLTVYIITIIFGFVPIFLHRFS--EYTE-SRKFGNVMFHVVPPGLNPIIYGLQAKEIKDKMLKLCVK-KVNPS-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q90426-1", "uniprot_id": "Q90426_DANRE", "id": "Q90426-1", "name": "", "aln": "-MDNQTFRSSTLLMEGLQVANQYRQLAFIFVLIAYIFIMIFNIGLLIQISSEKSLHQPMYILLCNLPLNDVFGTTLLLPRLLRNILLEPSERYITYVECVIQAFFGHLYGTTCHTILMIMAFDRYVAICNPLRYPAVMTSNMVVHLSAAAWGVAVVLVGILIGLTVRLSFCR-SVIENPFCDNASLFKLSCESTAINNIYGLSFTVVLLTSSLGSIALTYLRIAIVCFKSKNKATNSKAIKTCSTHLAVYLIMMVSGLTTITLHRFP--ELSD-SRKLSSIIKHIVPPCLNPIIYGLQVKEIRQRLFKLISKSKVNFM-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q2PRD7-1", "uniprot_id": "Q2PRD7_DANRE", "id": "Q2PRD7-1", "name": "Olfactory receptor", "aln": "MYPNGSVFPLVLTLQSLELPQMSIYPAFIFGLTTYLFILFCNLTIVITICLNRSLHKPMYILLLNMPINDTMAATNFFSQLLYSIWSQDTS--ISYPACLLQGFIVHLYGGASYVILTAMAYDRYIAICCPLRYGAIMNSNNLIKIITGMWVFNFTVITVLFSLLLPYKICR-THMTDLFCYNPSIMKLMCEDTTVNNIIGLISLVLYHCIALSVVAFTYIHILITCVTNKQSDAKMKALQTCGTHLVVFLFLEFNTLFPLVAHRSE--SVPAYLRRVFSITVFVFPPIINPLVYGFKTKEIRQKMLTCFKRKMTSL--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : * . : : * :: : : * **:.:: : : : . : :. * * : : * *::** :** ** * :: : : . * : . * : .* * : :* * . . * ** *: : . . : : * :**::* . :: ", "identical_positions": 31, "similar_positions": 49, "identity": "9.72%" }, { "cls_id": "homologset.agr.MGI:1333766", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CHU3-1", "uniprot_id": "EPN2_MOUSE", "id": "Q8CHU3-1", "name": "Epsin-2", "aln": "---------MTTSSIRRQMKNIVNNYSEAEIKVREATSNDPWGPSSSLMTEIADLTYNVVAFSEIMSMVWKRLNDHGKNWRHVYKALTLLDYLIKTGSERVAQQCRENIFAIQTLKDFQYIDRDGKDQGINVREKSKQLVALLKDEERLKVERVQALKTKERMAQVATGVGSN-QITFGRGSSQPNLSTSYSEQEYGKAGGSPASYHGS---------------------------------------------------------TSPRVSSELEQARPQTSGEEELQLQLALAMSREVAEQSSESVQTARGSKEERLRRGDDLRLQMALEESRRD-------TVKVPKKKE------AKACCKPGSHSQQTTLLDLMD----------ALPSSGPVTQKTEPWS--------------------------------AGASANQTNPWGGTVAPSNITDPWP-SFG--TKPAASVDPWG------------------VPTTASTQSVPKNSDPWAAS---QQPASNAGK-TTDAWGAA---KPSSAS--GSFELFSN-FNGTVKDDFSEFDNLRTSKKPAES--GASVPPQDSRTTSPDLFESQS---------LTSASSKPSSARKTPESFLGPNAALVNLDSLVTKPAPPAQSLN-----PFLAPG-----------AAAP-APVNPFQVNQPQPLTLNQLRGSPVLG-----------------------SSAS-FGSGP--GVET--VAPMTSVAP--------------------------------------------------------------------------------------------HSSVGASGSS-LTPLGPTAMNM-----------VGSVGIPPS-------------AAQSTGTTNPFLL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Z1Z3-1", "uniprot_id": "EPN2_RAT", "id": "Q9Z1Z3-1", "name": "Epsin-2", "aln": "---------MTTSSIRRQMKNIVNSYSEAEIKVREATSNDPWGPSSSLMTEIADLTYNVVRFSEIMSMVWKRLNDHGKNWRHVYKALTLLDYLIKTGSERVAQQCRENIFAIQTLKDFQYIDRDGKDQGINVREKSKQLVALLKDEERLKVERVQALKTKERMAQVATGVGSN-QITFGRGSSQPNLSISHSEQEYGKAGGSPASYHGS---------------------------------------------------------TSPRVSSELEQARPQTSGEEELQLQLALAMSREVAEQ------------EERLRRGDDLRLQMALEESRRD-------TVKVPKKKE------VKACCKPGSHSQQTTLLDLMD----------ALPSSGPVAQKTEPWS--------------------------------TGTPANQTNPWGGTVAPANISDPWP-SFG--TKPAASVDPWG------------------VPTTASIQSVPKNSDPWAAS---QQPASDAGK-TADAWGAA---KPSPAS--GSFELFSN-FNGTVKDDFSEFDNLRTSKKPAES--GASVPPQDSRTTSPDLFESQS---------LTSASSKPSSARKTPESFLGPNAALVNLDSLVTKPAPPAQSLN-----PFLAPG-----------AAAP-APVNPFQVNQPQPLTLNQLRGSPVLG-----------------------SSAS-FGSGP--GVET--VAPMPSVAP--------------------------------------------------------------------------------------------HSALGATGSS-LTPLGPTAMNM-----------VGSMGIPPS-------------AAQPAGTTNPFLL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O95208-1", "uniprot_id": "EPN2_HUMAN", "id": "O95208-1", "name": "Epsin-2", "aln": "---------MTTSSIRRQMKNIVNNYSEAEIKVREATSNDPWGPSSSLMTEIADLTYNVVAFSEIMSMVWKRLNDHGKNWRHVYKALTLLDYLIKTGSERVAQQCRENIFAIQTLKDFQYIDRDGKDQGINVREKSKQLVALLKDEERLKAERAQALKTKERMAQVATGMGSN-QITFGRGSSQPNLSTSHSEQEYGKAGGSPASYHGSPEASLCPQHRTGAPLGQSEELQPLSQRHPFLPHLGLASRPNGDWSQPCLTCDRAARATSPRVSSELEQARPQTSGEEELQLQLALAMSREVAEQ------------EERLRRGDDLRLQMALEESRRD-------TVKIPKKK------------EHGSLPQQTTLLDLMD----------ALPSSGPAAQKAEPWG--------------------------------PSASTNQTNPWGGPAAPASTSDPWP-SFG--TKPAASIDPWG------------------VPTGATVQSVPKNSDPWAAS---QQPASSAGKRASDAWGAVSTTKPVSVS--GSFELFSN-LNGTIKDDFSEFDNLRTSKKTAES--VTSLPSQNNGTTSPDPFESQP---------LTVASSKPSSARKTPESFLGPNAALVNLDSLVTRPAPPAQSLN-----PFLAPG-----------APATSAPVNPFQVNQPQPLTLNQLRGSPVLG-----------------------TSTS-FGPGP--GVESMAVASMTSAAP--------------------------------------------------------------------------------------------QPALGATGSS-LTPLGPAMMNM-----------VGSVGIPPS-------------AAQATGTTNPFLL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58J3E6-1", "uniprot_id": "A0AC58J3E6_DANRE", "id": "A0AC58J3E6-1", "name": "", "aln": "---------MPSSTIRRQMKNVVNNYSEPEKKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMIWKRLNDHGKNWRHVYKALTLLDYLIKTGSERVALQCKENIFAIQTLKDFQYIDRDGKDQGINVREKSKQLVVLLKDDDRLKGERSQALKTKERMAQVATSVGSNNQIGFGRGSSQPNLSTSYS-EEYGKSEGSPASYHGS---------------------------------------------------------TSPNASSELEQARPQTSGEEELQLQLALAMSREAAEQ------------EERMRRGDDLRLQMALEESRKDTS-----TGKVSKKKKEA---LMSVVVGVCAQPPQSSLMDLMD----------AVP-EGHANQGTDPWG--------------------------------AGAAA----------AAGPTSDPWQ-SYGAAPKPAAPVDPWG------------------LPGASSSATPVKSTDPWGSS---SAPA------AADPWGPMPATRPKAPATVGSFDLFST-PNGSSREDFSEFDSIRSSALTGDGRGSSALPSQASLSIGSDLFEVP---------------SGP--TRKTPESFLGPNAALVNLDSLVSKPLQQAPVSN-----PFLAGASGVASAPVPAPAPAPAAQVNPFQVNQPQPPTLNQMRVSPMMG-----------------------MSAQGFNSMIQRSNEPLPLSSLPPGGP--------------------------------------------------------------------------------------------VSMVPMTGMAPLGPMGQMMPSMGIPAS--MPQPLMSTGLPPTGA-----------AAQPGSTTNPFLL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VS85-1", "uniprot_id": "Q9VS85_DROME", "id": "Q9VS85-1", "name": "", "aln": "MRKQKDDMQVNVAGLRRNIKNLAHNYSDAQVKVREATSNDPWGPSAAIMSEIAELTYNVVAFSEIMQMIWKRLNDHGKNWRHVYKALILLEYLIKTGSEKVAQQCKENIFAIQTLREFVYFE-EGKDQGTHVREKAKQLVTLLKDDERLKNERVKAQKAKERFAQNPSGFGSD---GYIDGPSQRDLPPGWQEE-------------------------------------------------------------------------PPKSVSELEMVRPQTAGEEELQLQLAMAMSREEAEQ------------EEAKRRSDDVRLQLALSQSEQDFKDPNGRPIPAPKKEEQQSHLLDLLDISLGATSISSPPLGAAGGAPTAVVDPWAMPGPRAPSQLSDPWSGTSSPQVDPWNPSAAPRTILGAGVPMTSAPLGAGNDAWGARTQSPSVASGSSNEGWLQSNGNANQNGRGATPAGPPAEGWLIKSTAVGALGAAPINHAANNGSSSSDPWLAEPAASAAGGAAAVGLADPWAPGAASQTGAGALDDPWKALGTGAIKKQSPEFDEFDLITNRNKSEHSNSNASNNNNASLLDDMDPLSANYGNGGINSSMHPSTGATAKKSIKDAHSFLGENSALVNLDNLIKPIAPQTQTGNQPAYNPFSDNVVPPKTN-LFQQQQPAVPSINQLKQQAPFSVSMNQDPWAPVMGGVSTTSQPKLPPPVRPTSLNLGPSSVGEFQLLSALSNPIIPIAHIPQPQPNLQVYNNAYQSSSSTNILGKSNIPTNMNSSTSNSTIHSCYASPSPGVDGIRNMDIFTERPYYNSPTAPADDTYMYNSRDNNNINSNYGTPSLYSSFAASYSSALSDSLAETPGISVAPLGFVADTVMSFGPSSSSANCKLEQNNNMPWIKPEAATNPFLS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12518-1", "uniprot_id": "ENT1_YEAST", "id": "Q12518-1", "name": "Epsin-1", "aln": "----------MSKQFVRSAKNLVKGYSSTQVLVRNATSNDNHQVSKDSLIELAEKSYDSADFFEIMDMLDKRLNDKGKYWRHIAKALTVIDYLIRFGSENCVLWCRENLYIIKTLKEFRHEDDEGIDQGQIVRVKAKELTALLSDDERLNEERNMNIKGRNRKGRRRRGTGRS--------------------------------------------------------------------------------------------------------------DENDDDLQRAISASRLTAEE-------------DERRRKQDEDYETALQLSKEE--------------------------------EELKRLQDLQR-----------MQQQQGQQQLQQPMY---------------------------------------------------------------------YDIFG---------------------------NPITPEEYAQFQLQQQQQQQQQQLQQQPMYYDVFGNPITPEELAQFQQQQQLQEQQYLASMQQQQQAMSNNPFAKSEQSSSSPKRNQLVAASSPQQLQQ--------------------QKQQEPLIQNRTGNQSMTDKYSKLNELLATGTG----------------------------IDTFGNVGEARIPAQHTKTGTFIN-----------------------SQGTGYRQVSDDPNHNPFLNSQYTGLP-------------------------------------------------------------------------------------------STSVVPTQTGYGFGNQSQQQSQNN--------------------------------GSNNRGYTLIDL-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *. **:.:.**..: **:***** * : *:*: :*: . * ***.*: *****:** ***: *** :::***: ***. . *:**:: *:**::* : : :* *** ** *:*:*..**.*::**: ** * ::* .: . * . .*:: :** *:: ** **: : ** :* : **. *..: . . : * :* * ..: : . :. .. . :. .:.: : . .. :: . . . . * ..:: .:. .: . . . :: : . :: ...:. . : : * . . : : . * * ", "identical_positions": 87, "similar_positions": 124, "identity": "9.45%" }, { "cls_id": "homologset.agr.MGI:1333768", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4FZU2-1", "uniprot_id": "K2C6A_RAT", "id": "Q4FZU2-1", "name": "Keratin, type II cytoskeletal 6A", "aln": "-MSTKTVIRSQTS-HRGFSAGSARLPGLNRSGFSSVSVCRSRGSGGS-------RAVCGGAGFGSRSLCGVGSSQRISIGGGSCGIGGGYGGRFG---------GSFGYGGGAGGSLGFGAGAGFGGGYGGAGFPVCPPGGIQEVTINQSLLTPMNLQIDPTIQRVRTEEREQIKTLNNKFASFIDKVRFLEQQNKVLDTKWALLQEQGTKTVRQGLETLFEQYINDLRKELDNILGQRGRLDSELRNMQGTVEDYKSKYEDEINRRTAAENEFVTLKKDVDAAYMNKVELQAKADSLTDEINFLRALYEAELSQMQTHISDTSVVLSMDNNRSLDLDSIIAEVKAQYEEIAKRSRAEAESWYQTKYEELQITAGRHGDDLRNTKQEISEINRMIQRLRSEIDHVKKQIANLQAAIAEAEQRGEMALKDARGKLEGLEDALQKAKQDMARLLKEYQDLMNVKLALDVEIATYRTLLEGEECRLNGEG-VGPVNISVVQSTVSSSYGSAGGASSSIGLGGSSSFSYGGSHSIGGGFSAGSGRGISSGLSSSGG-----SSSTIKYTT-TSSTRKSYRP----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6AP90-1", "uniprot_id": "A0A8I6AP90_RAT", "id": "A0A8I6AP90-1", "name": "", "aln": "-MSTQTVIRSQTS-HRGFSAGSARLPGLTRSGFSSVSVCRSRGSGGS-------RAVCGGAGFGSRSLCGVGSSKRISIGGGSCGIGGGYGGRFG---------GSFGYGLGAGGSLGFGAGAGFGGGYGGAGFPVCPPGGIQEVTINQSLLAPMNLQIDPTIQRVRTEEREQIKTLNNKFASFIDKVRFLEQQNKVLDTKWALLQEQGTKTVRQGLETLFEQYINNLRRQLDNIRGQRGRLDSELRNMQGTVEDYKSKYEDEINRHSYAENEFVTLKKDVDAAFMRKVELQGNADSLADEVNFLRVIFEAELSQMQTRISDTSVVLSMDNNRSLDLDSIIAEVKAQYEEIAKRSRAEAESWYQTKYEELQITAGRHGDDLRNTKQEISEINRMIQRLRSEIDHVKKQIAKLQAAIAEAEQRGEMALKDARGKLEGLEDALQKAKQDMARLLKEYQDLMNVKLALDVEIATYRTLLEGEECRLNGEG-VGPVNISVVQSTMSSGYGSAGGASSSIGLGGGSSFSYGGSHSIGGGFSAGSGRGISSGLSSSGG-----SSSTIKYTT-TSSTRKSYRP----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I5ZMI8-1", "uniprot_id": "A0A8I5ZMI8_RAT", "id": "A0A8I5ZMI8-1", "name": "", "aln": "-MSTKTVIRSQTS-HRGFSAGSARLPGLTRSGFSSVSVCRSRGSGGS-------RAVCGGAGFGSRSLCGVGSSKRISIGGGSCGIGGGYGGRFG---------GSFSYGGGAGGSFGFGAGAGFGGGYGGAGFPVCPPGGIQEVTINQSLLIPMNLQIDPTIQRVRTEEREQIKTLNNKFASFIDKVRFLEQQNKVLDTKWALLQEQGTKTVRQNLEPLFEQYINNLRRQLDSILGERGRLDSELRNMQGTVEDYKSKYEDEINRRTAAENEFVTLKKDVDAAYMNKVELQAKADSLTDEINFLRALYEAELSQMQTHISDTSVVLSMDNNRSLDLDSIIAEVKAQYEEIAKRSRAEAESWYQTKYEELQITAGRHGDDLRNTKQEISEINRMIQRLRSEIDHVKKQIANLQAAIAEAEQRGEMALKDARGKLEGLEDALQKAKQDMARLLKEYQDLMNVKLALDVEIATYRTLLEGEECRLNGEG-VGPVNIAVVQSTMSSGYGSAGGASSSIGLGGGSSFSYGGSHSIGGGFSAGSGRGISSGLSSSGG-----SSSTIKYTT-TSSTRKSYRP----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6G380-1", "uniprot_id": "A0A8I6G380_RAT", "id": "A0A8I6G380-1", "name": "", "aln": "-MSTKTTIRSQTS-HRGFSAGSARLPGLNRSGFSSVSVCRSRGSGGS-------RAVCGGAGFGSRSLYGVGSSQRISVGGGSCGIGGGYGSRFG---------GSFGYGLGAGGSLGFGAGAGFGGGYGGAGFPVCPPGGIQEVTINQSLLTPMNLQIDPTIQRVRTEEREQIKTLNNKFASFIDKVRFLEQQNKVLDTKWALLQEQGTKTVRQNLEPLFEQYINNLRRQLDSILGERGRLDSELRNMQGTVEDYKSKYEDEINRRTAAENEFVTLKKDVDAAYMNKVELQAKADSLTDEINFLRALYEAELSQMQTHISDTSVVLSMDNNRSLDLDSIIAEVKAQYEEIAKRSRAEAESWYQTKYEELQITAGRHGDDLRNTKQEISEINRMIQRLRSEIDHVKKQIANLQAAIAEAEQRGEMALKDARGKLEGLEDALQKAKQDMARLLKEYQDLMNVKLALDVEIATYRTLLEGEECRLNGEG-VGPVNISVVQSTMSSGYGSAGGASSSIGMGGGSSFSYGGSHSIGGGFSAGSGRGISSGLSSSGG-----SSSTIKYTT-TSSTRKSYRP----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z331-1", "uniprot_id": "K2C6B_MOUSE", "id": "Q9Z331-1", "name": "Keratin, type II cytoskeletal 6B", "aln": "-MSTKTTIKSQTS-HRGYSASSARVPGLNRSGFSSVSVCRSRGSGGS-------SAMCGGAGFGSRSLYGVGSSKRISIGGGSCGIGGGYGSRFGGAYGSR-FGGSFGIGGGAGSGFGFGGGVGFGGGYGGAGFPVCPPGGIQEVTINQNLLTPLNVQIDPTIQRVRTEEREQIKTLNNKFASFIDKVRFLEQQNKVLDTKWALLQEQGTKTVRQNLEPMFEQYISNLRRQLDSIIGERGRLDSELRNMQDTVEDYKSKYEDEINKRTKAENEFVTVKKDVDAAYMTKVELQAKADSLADEINFLRVIYEAELSQMQTHISDTSVVLSMDNNRSLDLDSIIAEVKAQYEDIAQRSRAEAESWYQTKYEELQVTAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKKQCANLQAAIADAEQRGEMALKDARGKLEGLEDALQKAKQEMARLLKEYQELMNVKLALDVEIATYRKLLEGEECRLNGEG-VGPVNISVVQSTVSSGYGSAGGASSSLGLGGSSSYSYGSSHGLGGGFSAGSGRAIGGGLSSSGGL----SSSTIKYTTSASSSRKSYRH----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P04259-1", "uniprot_id": "K2C6B_HUMAN", "id": "P04259-1", "name": "Keratin, type II cytoskeletal 6B", "aln": "MASTSTTIRSHSSSRRGFSANSARLPGVSRSGFSSISVSRSRGSGGL-------GGACGGAGFGSRSLYGLGGSKRISIGGGSCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGFGLGGGAGLAGGFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPAIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLDTKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDNIVGERGRLDSELRNMQDLVEDLKNKYEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEINFLRALYDAELSQMQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWYQTKYEELQITAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKKQCANLQAAIADAEQRGEMALKDAKNKLEGLEDALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRLNGEG-VGQVNISVVQSTVSSGYGGASGVGSGLGLGGGSSYSYGSGLGVGGGFSSSSGRATGGGLSSVGG-----GSSTIKYTTTSSSSRKSYKH----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P48668-1", "uniprot_id": "K2C6C_HUMAN", "id": "P48668-1", "name": "Keratin, type II cytoskeletal 6C", "aln": "MASTSTTIRSHSSSRRGFSANSARLPGVSRSGFSSISVSRSRGSGGL-------GGACGGAGFGSRSLYGLGGSKRISIGGGSCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGFGLGGGAGLAGGFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPAIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLDTKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLDSELRNMQDLVEDLKNKYEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEINFLRALYDAELSQMQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWYQTKYEELQVTAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKKQCASLQAAIADAEQRGEMALKDAKNKLEGLEDALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRLNGEG-VGQVNVSVVQSTISSGYGGASGVGSGLGLGGGSSYSYGSGLGIGGGFSSSSGRAIGGGLSSVGG-----GSSTIKYTTTSSSSRKSYKH----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P02538-1", "uniprot_id": "K2C6A_HUMAN", "id": "P02538-1", "name": "Keratin, type II cytoskeletal 6A", "aln": "MASTSTTIRSHSSSRRGFSANSARLPGVSRSGFSSVSVSRSRGSGGL-------GGACGGAGFGSRSLYGLGGSKRISIGGGSCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGFGLGGGAGLAGGFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPTIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLDSELRGMQDLVEDFKNKYEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEINFLRALYDAELSQMQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWYQTKYEELQVTAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKKQCANLQAAIADAEQRGEMALKDAKNKLEGLEDALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRLNGEG-VGQVNISVVQSTVSSGYGGASGVGSGLGLGGGSSYSYGSGLGVGGGFSSSSGRAIGGGLSSVGG-----GSSTIKYTTTSSSSRKSYKH----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NWF6-1", "uniprot_id": "K2C8_DANRE", "id": "Q6NWF6-1", "name": "Keratin, type II cytoskeletal 8", "aln": "-MSTYSKKTSYTV--KSSS------SGSIPRNFSSLSYSGPSMSRQS-------------------------YSARSSYGGVNRGMGAGMGGGSGFI-----SSS-----------SAYGLGMGMGTGMGAG--VVAP---IQAVTVNKSLLAPLNLEIDPNIQIVRTQEKEQIKTLNNRFASFIDKVRFLEQQNKMLETKWSLLQNQ--TATRSNIDAMFEAYIANLRRQLDSLGNDKMKLEADLHNMQGLVEDFKNKYEDEINKRTECENEFVLIKKDVDEAYMNKVELEAKLESLTDEINFLRQIFEEEIRELQSQIKDTSVVVEMDNSRNLDMDAIVAEVRAQYEDIANRSRAEAEMWYKSKYEEMQTSANKYGDDLRSTKTEIADLNRMIQRLQSEIDAVKGQRANLENQIAEAEERGEMAVRDAKGRIKDLEDALQRAKQDMARQIREYQDLMNVKLALDIEIATYRKLLEGEEDRLATG--IKAINISK-QSTSYGGYPMESAGSSYSTYSSGYSSGLSGGYGGG--YSGGYSGGYSSGSGYSDTVSQTKKSVVIKMIETKDGRVVSESSEVVQD-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1QV31-1", "uniprot_id": "F1QV31_DANRE", "id": "F1QV31-1", "name": "", "aln": "-MSTSFKTFTSSG--SMSGGMGGGMGGGIRKNFSSMSTSAVPMGSRSSVSFRRSGGGGGGGGFGAGSGGSFSYSMGGGGGGGGSGFGGGFGSGGGFG-----SGGGFGGGAGFGGGSAYGGGAGFGGGFGPG--GVVP---ITAVTVNQNLLAPLNLEIDPNIQVVRTQEKEQIKTLNNRFASFIDKVRFLEQQNKVLETKWSLLQEQ--TTTRSNIDAMFEAYIANLRRQLDGLGNEKMKLEGELKNMQNLVEDFKNKYEDEINKRAAVENEFVLLKKDVDAAYMNKVELEAKVDSLQDEINFLRAIFEEELRELQSQIKDTSVVVEMDNSRNLDMDAIVAEVRAQYEDIANRSRAEAESWYKQKFEEMQSSAGKYGDDLRNTKAEIADLNRMISRLQNEIEAVKGQRANLEAQIAEAEERGELAVKDAKLRIKDLEDALQRAKQDMARQVREYQELMNVKLALDIEIATYRKLLEGEESRIASGGNTATIHIQE-SSSSSGGGGGGFGYGGGSGYGGGSGFGGGSGYGGGSGFGGGSGFGYGGGSGMS-----IGGGSGMSMSGGGGGQISMSRSSIVSSQKRRF", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** : : . * .***:* . . * . ** . .:..* *. * . . * * *:. * * * * * **:*:.** *:*::*** ** **::*:********:****************:*:***:***:* .:.*..::.:** ** :**::**.: .:: :*:.:*:.**. *** *.*******::: ***** :***** *:* ****:.: ::* **:**** ::: *: ::*::*.*****:.***.*.**:*:*:***:****:**:******* **: *:**:* :*.::*****.** **:::****.**:.**: ** * *.*: **:**:***:*::**: :::.******:***::** ::***:*********:******.****** *: ::: .*: .. . .. ... . . ... . * :... . . ..* . . :. .. ", "identical_positions": 225, "similar_positions": 156, "identity": "38.33%" }, { "cls_id": "homologset.agr.MGI:1333770", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q2PRI1-1", "uniprot_id": "Q2PRI1_DANRE", "id": "Q2PRI1-1", "name": "", "aln": "-MDNLTFRHSVLLVEGLKVTHQSSQPVFIVLFLSYIFAMISNITLIFLISTEKNLHDPMHFLFCNLPVNDIIGTTVILPRLMQDVLKEASERYISYTECVVQAYFVHVFTAACHYVLMIMAFDRYVAICNPLRYTAIMTNKMVIKLSASAWGLAIIVVTVMIGLTLRLSHCRS-TIENPFCDNASLFKLSCENVSINNAFGVVYSVIVACLSAISIFITYVKIATVCLASKNKALNSKAMKTCSTHLAVYLIMFVSGAIFIFLHRF--PEYAE-SRKLGSIMFHIVPPGLNPLVYGLQTKEIRQRFVKLCRRKTSTSLM--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q2PRH9-1", "uniprot_id": "Q2PRH9_DANRE", "id": "Q2PRH9-1", "name": "", "aln": "-MDNLTFTNSILLVEGLKVTPQSSQPVFIMFLLAYIFAMVSNIGLIFLISTEKNLHDPMHFLFCNLPLNDIMGTTVIMPRLLQDILTEASERYISYAECAIQAYFVHVFTAACHYVLMIMAFDRYVAICNPLRYTAIMTNKMVIGLSALAWGLAIIFVTIMVGLSLRLSRCRY-KIENPFCDNASLFKLSCENVSVNNVFGLVYTVIVLSLSALSIFVTYVKIATVCVTSKNKALNSKAIKTCSTHLAVYLIMFVTGAVFIFLHRF--PEYSD-NRKLASIMFHIVPPGLNPLVYGLQTKEIRQKVVKLWCRKKSMIT---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q2PRH7-1", "uniprot_id": "Q2PRH7_DANRE", "id": "Q2PRH7-1", "name": "", "aln": "-MDNLTFTNDFLLVEGLKVTYPSSYPIFILLFLFYIFAMGCNIGLIILIATEKKLHHPMHFLFCNLPVNDIIGTTVILPRLICDIFKQTSERSMTYVECVVQAYFVHIFTTASHTALVTMAYDRQVAICNPLLYTAVMTDKMVVKLSATAWTLPIIVVAVMIGLTVRLSRCRS-KIENPFCDNASLYKLSCENVAINNIFGIVYSVAALIISVALMVIAYARIVTACIISKSKALNSKAIKTCSSHIAVYLIMFVSCAIMIFFHRF--PEYSE-NRKLASIMFHIVPPGLNPIVYGLQTKEIRQIIVKRWWKNAVDKL---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q32PT6-1", "uniprot_id": "Q32PT6_DANRE", "id": "Q32PT6-1", "name": "", "aln": "-MDNRTFRYSTLLVEGLQITQQSSQLTFIFLLTVYVFSMVSNIGILIQILAEKSLHQPMYILFCHLPMSDIIGATVLIPRLLKDLLTDPSERYITYIECVLQAFFTHLYGTTSHTILMIMAFDRYVAICNPLRYPTIMNNKMIVKLSAGAWGAAIVLVGILIGLSVRLSHCRS-VIENHVCDNPSLFKLSCENTFINNVYGLTFTVVLLTSSLGWVVLTYLRIAMVCIKSKHKATNSKAIKTCTTHLTVYIITIIFGFVPIFLHRF--SEYTE-SRKFGNVMFHVVPPGLNPIIYGLQAKEIKDKMLKLCVK-KVNPS---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q90426-1", "uniprot_id": "Q90426_DANRE", "id": "Q90426-1", "name": "", "aln": "-MDNQTFRSSTLLMEGLQVANQYRQLAFIFVLIAYIFIMIFNIGLLIQISSEKSLHQPMYILLCNLPLNDVFGTTLLLPRLLRNILLEPSERYITYVECVIQAFFGHLYGTTCHTILMIMAFDRYVAICNPLRYPAVMTSNMVVHLSAAAWGVAVVLVGILIGLTVRLSFCRS-VIENPFCDNASLFKLSCESTAINNIYGLSFTVVLLTSSLGSIALTYLRIAIVCFKSKNKATNSKAIKTCSTHLAVYLIMMVSGLTTITLHRF--PELSD-SRKLSSIIKHIVPPCLNPIIYGLQVKEIRQRLFKLISKSKVNFM---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q2PRD7-1", "uniprot_id": "Q2PRD7_DANRE", "id": "Q2PRD7-1", "name": "Olfactory receptor", "aln": "MYPNGSVFPLVLTLQSLELPQMSIYPAFIFGLTTYLFILFCNLTIVITICLNRSLHKPMYILLLNMPINDTMAATNFFSQLLYSIWSQDTS--ISYPACLLQGFIVHLYGGASYVILTAMAYDRYIAICCPLRYGAIMNSNNLIKIITGMWVFNFTVITVLFSLLLPYKICRT-HMTDLFCYNPSIMKLMCEDTTVNNIIGLISLVLYHCIALSVVAFTYIHILITCVTNKQSDAKMKALQTCGTHLVVFLFLEFNTLFPLVAHRS--ESVPAYLRRVFSITVFVFPPIINPLVYGFKTKEIRQKMLTCFKRKMTSL----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q2PRE9-1", "uniprot_id": "Q2PRE9_DANRE", "id": "Q2PRE9-1", "name": "Olfactory receptor", "aln": "-MDNSTYFTTVILTGYIDIG-DIKYLCFVVLILLFAAIIVANLFIIGIICKEKSLHEPMYVFLCSLCANQLCGSFALFPFVLGNMLRSKTP-EVPLTVCHAQIFALYTYGQVEFCNLAMMSYDRYVAICHPLEYHRIMSPARTMTLIALGWSLQIIIFSLSFSVNVQLKLCGN-VLDKVWCDQYMLVKLACSDTTPNNIAGMTGIAVTIGAPLLLILFSYAKILRVCLKFKGQTAQ-KSLYTCILHLISLLNFAVGCSFELIQSRFGKLPMPAVVRVILSLYFLVCPPLFNPIMYGVRLANIKKALKKMICM---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0ACD6B7K1-1", "uniprot_id": "A0ACD6B7K1_DANRE", "id": "A0ACD6B7K1-1", "name": "Olfactory receptor", "aln": "-MENGANFTFIRLTGYLNLDFKMKYFLFAVLTVLYLTIICANSFLIGVICLAKILHKPMYMFLCSLFVNELYGSTALFPSLQVNLLLNDN--TISLVYCYLQIFCLCTYAMIDFCTLAVMSFDRYVSICYPLQYNKIMTPFRVGLLIALVWTYCFIQFFIFLSFKFKLQLCGN-VMEKVWCDNYLLVNLACSKSSLHNAYGIYLAVVTAVIPLTLIFYSYTRIIKICLSFSKEAKK-KALSTCTPHIISLLNFTLGCFFETLQSRFDEIRTPALIRVIVSLYLLMCQPLLNPILYAIRLKNIRLVCKNLVLSKIGIA----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q2PRG1-1", "uniprot_id": "Q2PRG1_DANRE", "id": "Q2PRG1-1", "name": "", "aln": "-MENYTSFNFMLFEN---LG-YIRYSLFVLGFVLYFAIIFFNVLIMLAVFLERTLHQPMYILISCLSMNSLFGTAGFFPRVLSDLLSETH--SISREACFSQSFVIFTYVANEFSILMLMAFDRFAAICKPLRYHSIVRPRFLACLIVINLNCIMILLCVAALLTTKLRMCGN-KLFKVYCHSYEVLKLSCDNILINNAFGLLLVIITTIIPLGLILLSYVKILIICQRSSAQFKG-KAYQTCIPHIVILLNFTIAVTCDTTLSRVVNLQIPVGLSVFLSLEFLIIPPVLNPLIYAFNLPDIRKKMISLIKPLK-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q2PRA7-1", "uniprot_id": "Q2PRA7_DANRE", "id": "Q2PRA7-1", "name": "", "aln": "-MDNNSSFSMFSLTALNGSR-SSRITIFSFALPGYFLTIFVNTLLILIIVLEKVLHQPMYIFLCNLCINGLYGATGFYPPLLYYLLSESN--VISLKECAIQSFAIFTYAIGEFTNLSVMAFDRYLAICRPLYYHNIMTTVTVWRLLTFIWMFPCCTAILLILMTLRFPICIK-KISKLYCETWVLERLVCGVDTAQFVFNG-ILTCAVNALVWFVFLSYINILVAC-KHSVQNHK-KFISTCLPHLIAFLNYVFWSLFSTLYELFGISSLSQEFKNFLSVTFMIIPPLINPVIYGIVLTPIRTKAKHVFQSFRPKHID--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9Y585-1", "uniprot_id": "OR1A2_HUMAN", "id": "Q9Y585-1", "name": "Olfactory receptor 1A2", "aln": "MKKENQSFNLDFILLGVTSQQEQNNVFFVIFLCIYPITLTGNLLIILAICADIRLHNPMYFLLANLSLVDIIFSSVTIPKVLANHLLGSKF--ISFGGCLMQMYFMIALAKADSYTLAAMAYDRAVAISCPLHYTTIMSPRSCILLIAGSWVIGNTSALPHTLLTASLSFCGNQEVANFYCDIMPLLKLSCSDVHFN-VKMMYLGVGVFSLPLLCIIVSYVQVFSTVFQVPSTKSLFKAFCTCGSHLTVVFLYYG----TTMGMYFRPLTSYSPKDAVITVMYVAVTPALNPFIYSLRNWDMKAALQKLFSKRISS-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9P1Q5-1", "uniprot_id": "OR1A1_HUMAN", "id": "Q9P1Q5-1", "name": "Olfactory receptor 1A1", "aln": "MRENNQSSTLEFILLGVTGQQEQEDFFYILFLFIYPITLIGNLLIVLAICSDVRLHNPMYFLLANLSLVDIFFSSVTIPKMLANHLLGSKS--ISFGGCLTQMYFMIALGNTDSYILAAMAYDRAVAISRPLHYTTIMSPRSCIWLIAGSWVIGNANALPHTLLTASLSFCGNQEVANFYCDITPLLKLSCSDIHFH-VKMMYLGVGIFSVPLLCIIVSYIRVFSTVFQVPSTKGVLKAFSTCGSHLTVVSLYYG----TVMGTYFRPLTNYSLKDAVITVMYTAVTPMLNPFIYSLRNRDMKAALRKLFNKRISS-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZFE0-1", "uniprot_id": "D3ZFE0_RAT", "id": "D3ZFE0-1", "name": "", "aln": "MREENESSTTEFTLLGVTRQREQEYFFFILFLFIYPITVFGNTLIILAIHSDIRLHNPMYFFLANLSLVDIFFSSVTIPKMLANHLLGSKA--ISFGGCMAQMFFMIGLANTDSYILAAMAYDRAVAISRPLHYATIMSPQLCILLVAGSWVIGNGNSLPHTILTARLSFCGNRDVANFYCDITPLLQLSCSDIRFN-VKMMYFGVGVFSVPLLFIIISYVRVFSTVLRVPSTKGFLKALSTCGSHLTVVSLYYG----TVMGMYFRPLASYSLKHALITVMYTTVTPMLNPFIYSLRNRDMKAALKKLFHCPSSSSSSST", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0KWI2-1", "uniprot_id": "A0ABK0KWI2_RAT", "id": "A0ABK0KWI2-1", "name": "", "aln": "MREENESSTTEFTLLGVTRQREQEYFFFILFLFIYPITVFGNTLIILAIHSDIRLHNPMYFFLANLSLVDIFFSSVTIPKMLANHLLGSKA--ISFGGCMAQMFFMIGLGNTDSYILAAMAYDRAVAISRPLHYATIMSPQLCILMVAGSWVVGNGNSLPHTILTARLSFCGNRDVANFYCDITPLLQLSCSDIRFN-VKMMYFGVGVFSVPLLFIIISYVRVFSTVLRVPSTKGFLKALSTCGSHLTVVSLYYG----TVMGMYFRPLASYSLKHALITVMYTTVTPMLNPFIYSLRNRDMKAALKKLFHRTSFLSPM--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TRX1-1", "uniprot_id": "Q7TRX1_MOUSE", "id": "Q7TRX1-1", "name": "", "aln": "MREENESSTTDFTLLGVTRQREQEYFFFILFLFIYPITVFGNMLIILAIHSDTRLHNPMYFFLANLSLVDIFFSSVTIPKMLANHLLGSKA--ISFGGCMAQMYFMIGLANTDSYILAAMAYDRAVAISRPLHYATIMSPQLCVLLVAGSWVIANANALPHTLLTARLSFCGNKDVANFYCDITPLLQLSCSDIRFN-VKMMYLGVGVFSVPLLCIIISYVRVFSTVLRVPSTKGFLKALSTCGSHLTVVSLYYG----TVMGMYFRPLTSYSLKHALITVMYTAVTPMLNPFIYSLRNRDMKAALKKLFHCPSSSSSLM-", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . : : * :: : **.**:.:: : : . : :. * * : * *::** :*. ** * :: : . . * : . * : .* * : : :* .: * ** *: . .: * :**.:*.. :: ", "identical_positions": 28, "similar_positions": 49, "identity": "8.72%" }, { "cls_id": "homologset.agr.MGI:1333772", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZIB0-1", "uniprot_id": "D3ZIB0_RAT", "id": "D3ZIB0-1", "name": "", "aln": "MCLAPWLSVASAVCSHFYHRLLRTYFKDRLTRFKFTFYIVQLLSGIGSHPNLKAPKIKLDCEDPLIRAYESFGENMLLLQCRNTASPPKPCDMV---KMSLL-VFLGLLGVSAAMP--MPMPRMPGFSSKSEEMMRYNQFNFMNAPPMMHMGPWQNGLPMPPHMPPQYPPYQMPMWPPPVPNGWQ--QPPMPNFPSKTEQTQETAKPNQTDPQEPQPQKQPLKEPPNEAARAKDEAQPPQPFPPFGNGLYPYQQPPWPIPQTGPPTGFGRPKFSNEEG-NPYYAYFGYHGFGGRP-YYSEEMFE-DYEKPKEKDPPKPEDPPPDDPPPEASTNSTVPDANATQSIPGGGQGGNDSSPVGNTGPGPNAGNNPTVLNGVFPLPKVNVSGQGVPKNQIPWRPSQPNIYENYPYP---NYPSERQWQTTD-TQGPKQNGPGYQNPQIQRGPQWNSFAWEGKQATTHPGNPTYHKPSPPTSRVNYPNYAGNPVNFGRKLPGPKKPFMGANPASNKPFVGANPASNKPFVGTNPASNKPFVGANPASNKPFVGANPASNKPFVGANPASNKPFVGANPASNKPFMGTNPAANKPSIGTNAASNKPFVGTNAGTNKPFMGINVASNKPFMGTNPASNKPFVGTNPASNKPFVRSNHASNKPFVGANAASNKPFVGTNVPSVGPKQVTVSHNMKTQNPKEKSLGQKERTVTPTKDTGNPWRSSKQYGINNPNYNLPHPEGSMVGPNFNSFDQQENTYFSRGDSRKVASPNRQIQSQNLPKGIALEPRRTPFESETKRPELKHSTNMP-VYPKKNPSPTRGHFPAGRNNWNHQKTLPPLKEGHGRKEENLRHPPYGSRGNVFYHEYNNPYPNEKSPYLRGNTWDKRISTPGTMMQPENPQYTMSSLDQKETEQYNEEDPIDPNEDESFPGQSRWGDDELSFKGNPTLRQYEGEQYTSTLAKEYLPYSLSNPPKPSEDFPYSEFYPWNPHETFPIYNPGPTIAPPVDPRSYYVNNAVGQEESTLFPSWTSWDHRNQAERQKESEPYFNRNVWDQSMSLHKSNIQNP----NHPYSTTSPAGFPKDPTWLEGENLNYDLQITSLSQPEREQLAFPDLRPQSYPTGQNEDHLFHQSQRGSCCIGGSTGHKENVLALHDYTSSYGLPPRKTQEISPVHTESSYTKYAKPNVSPASILPNQRNISENKLTAESPNPSPFGDDVPTVRKNTPNSGKNQLETG-IIALSEASSSQPKNTACLKSDLGGDRRDVLKQFFEGTQLGERTAGLTPEQLVIGSPDKGSGPDGTHSEVQGSEGEMQQQRPPTIRKLPCFGSKLAKLHSSSTGPPTNNGGPSLPNGALSTPTESPDTLVGLATREQFKSINVDQLNADGHTTLESFQ-DTSQQDQAHGCLLLQA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O55196-1", "uniprot_id": "ENAM_MOUSE", "id": "O55196-1", "name": "Enamelin", "aln": "---------------------------------------------------------------------------MLLLQCRNPTSPPKPCGLVPNVKMSLL-VFLGLLGVSAAMPFQMPMPRMPGFSSKSEEMMRYNQFNFMNAPPMMPMGPYGNGMPMPPHMPPQYPPYQMPMWPPPVPNGWQ--QPPMPNFPSKTDQTQETAKPNQTNPQEPQPQKQPLKEPPNEAARAKDDAQPPQPFPPFGNGLYPYPQPPWPIPQRGPPTAFGRPKFSNEEG-NPYYAFFGYHGFGGRP-YYSEEMFE-DYEKPKEKDPPKPEDPPPDDPPPEASTNSTVPDANATQSIP---EGGNDTSPIGNTGPGPNAGNNPTVQNGVFPPPKVNVSGQGVPKSQIPWRPSQPNIYENYPYP---NYPSERQWQTTG-TQGPRQNGPGYRNPQVERGPQWNSFAWEGKQAT-RPGNPTYGKPPSPTSGVN---YAGNPVHFGRNLPGPNKPFVGANPASNKPFVGANPASNKPFVGANPASNKPFVGANPASNKPFVGANPASNKPYVGANPASNKPFIGANPAANKPSIGTNPAANKPSIGTNPAANKPFVRNNVG----------------------ANKPFVGTNPSSNQPFLRSNQASNKPFMRSNQASNKPFVGTNVASVGPKQVTVSHNMKTQNPKEKSLGQKERTVTPTKDASNPWRSAKQYGINNPNYNLPRSEGSMVGPNFNSFDQQENSYFSKGASKRVPSPNIQIQSQNLPKGIALEPRRTPFQSETKKPELKHGTHQP-AYPKKIPSPTRKHFPAERNTWNRQKILPPLKEDYGRQDENLRHPSYGSRGNIFYHEYTNPYHNEKSQYIKSNPWDK--SSPSTMMRPENPQYTMTSLDQKETEQYNEEDPIDPNEDESFPGQSRWGDEEMNFKGNPTVRQYEGEHYASTLAKEYLPYSLSNPPKPSEDFPYSEFYPWNPQETFPIYNPGPTIAPPVDPRSYYVNNAIGQEESTLFPSWTSWDHRNQAERQKESEPYFNRNVWDQSINLHKSNIPN------HPYSTTSPARFPKDPTWFEGENLNYDLQITSLSPPEREQLAFPDFLPQSYPTGQNEAHLFHQSQRGSCCIGGSTGHKDNVLALQDYTSSYGLPPRKNQETSPVHTESSYIKYARPNVSPASILPSQRNISENKLTAESPNPSPFGDGVPTVRKNTPYSGKNQLETG-IVAFSEASSSQPKNTPCLKSDLGGDRRDVLKQFFEGSQLSERTAGLTPEQLVIGIPDKGSGPDSIQSEVQGKEGEMQQQRPPTIMKLPCFGSN-SKFHSSTTGPPINNRRPTLLNGALSTPTESPNTLVGLATREQLKSINVDKLNADEHTTLESFQ-GTSPQD--QGCLLLQA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NRM1-1", "uniprot_id": "ENAM_HUMAN", "id": "Q9NRM1-1", "name": "Enamelin", "aln": "---------------------------------------------------------------------------MLVLRCRLGTSFPKLDNLVPKGKMKILLVFLGLLGNSVAMP--MHMPRMPGFSSKSEEMMRYNQFNFMNGPHMAHLGPFFG-----NGLPQQFPQYQMPMWPQPPPNTWHPRKSSAPKRHNKTDQTQETQKPNQTQSKKP-PQKRPLKQPSHNQPQPEEEAQPPQAFPPFGNGLFPYQQPPWQIPQRLPPPGYGRPPISNEEGGNPYFGYFGYHGFGGRPPYYSEEMFEQDFEKPKEEDPPKAE-----SPGTEPTANSTVTETNSTQPNPKGSQGGNDTSPTGNSTPGLNTGNNPPAQNGIGPLPAVNASGQGGPGSQIPWRPSQPNIRENHPYPNIRNFPSGRQWYFTGTVMGHRQNRPFYRNQQVQRGPRWNFFAWERKQVA-RPGNPVYHKAYPPTSRGNYPNYAGNPANLRRKPQGPNK-----------------------------------------------------------------------------------------------------------------------------------------HP----------------------------VGTTVAPLGPKPGPVVRNEKIQNPKEKPLGPKEQIIVPTKNPTSPWRNSQQYEVNKSNYKLPHSEGYMPVPNFNSVDQHENSYYPRGDSRKVPNSDGQTQSQNLPKGIVLGSRRMPYESETNQSELKHSSYQPAVYPEEIPSPAKEHFPAGRNTWDHQEISPPFKEDPGRQEEHLPHPSHGSRGSVFYPEYNPYDPRENSPYLRGNTWDERDDSPNTMGQKESPLYPINTPDQKEIVPYNEEDPVDPTGDEVFPGQNRWG-EELSFKGGPTVRHYEGEQYTSNQPKEYLPYSLDNPSKPREDFYYSEFYPWSPDENFPSYNTASTMPPPIESRGYYVNNAAGPEESTLFPSRNSWDHRIQAQGQRERRPYFNRNIWDQATHLQKAPARPPDQKGNQPYYSNTPAGLQKNPIWHEGENLNYGMQITRMNSPEREHSSFPNFIPPSYPSGQKEAHLFHLSQRGSCCAGSSTGPKDNPLALQDYTPSYGLAPGENQDTSPLYTDGSHTKQTRDIISPTSILPGQRNSSEK---RESQNP--FRDDVSTLRRNTPCSIKNQLGQKEIMPFPEASSLQSKNTPCLKNDLGGDGNNILEQVFEDNQLNERTVDLTPEQLVIGTPDEGSNPEGIQSQVQENESERQQQRPSNILHLPCFGSKLAKHHSSTTGTPSSDGRQSPFDGDSITPTENPNTLVELATEEQFKSINVDPLDADEHSPFEFLQRGTNVQDQVQDCLLLQA", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **:*:** :* ** .:* **.:* ******* *.*** * ************************.* * :**: . :* *:* ******* * ** *: :.. *: .**:***** *****:.::* ***:***:*.:: .:.:::*****.********:** **** *** **..:*** :***** ***:.:********** ******** *:*****:****.* .* .*.::****.::*:**. * :****:** **: ** *:****.. **: * * **.**** * .*********** **:*** *:** *** *. . * :** * *:* *::***:** **** **.: :****.* *. .*** * *****.:: *: **:* :* ***.*..:*** .* :* * ******.** **: :.***:. .***.::** :*:.**:**:.** * *****.**:**:*:.:* *::*...: * *********.* .** *::***::.****.: * .**:: ***:: **** **.*::*: **:**. **::*:* **.:****.:** **. .*:* *::.*.**: .:*.** : *.* *.:.: **** ******:**. ** ****.*** :*:.***.**:*:****:*:*. .********.**.** *** *******.*.*.** **...*:.**::.*.****** * ******** .***** **: *:* .******:***: *:*: :** :.:** : *:* * *******.:*** :. ****: :**:: * ***:**:* **** ******* *.*** *:* ***:***.****.* :.*: **::*:.*: * :: :**:****.*** **: ** ** * *.*.*:*:*** * **** *:.:.**** *.***.***.***** .::*:*.**..**.***..********* **:**.*:. :*:** .*.* *****..* :******: :* ***:**.* .: : :* ****.*:*** ***.**:****** *:** *:.:* :* .*. ** :.******", "identical_positions": 654, "similar_positions": 289, "identity": "46.65%" }, { "cls_id": "homologset.agr.MGI:1333773", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZRJ3-1", "uniprot_id": "D3ZRJ3_RAT", "id": "D3ZRJ3-1", "name": "Putative nucleotidyltransferase MAB21L1", "aln": "------MIAAQAKLVYHLNKYYNEKCQARKAAIAKTIREVCKVVSDVLKEVEVQEPRFISSLNEMDNRYEGLEVISPTEFEVVLYLNQMGVFNFVDDGSLPGCAVLKLSDGRKRSMSLWVEFITASGYLSARKIRSRFQTLVAQAVDKCSYRDVVKMVADTSEVKLRIRDRYVVQITPAFKCTGIWPRSAAHWPLPHIPWPGPNRVAEVKAEGFNLLSKECHSLAGKQ---SSAESDAWVLQFAEAENRLQMGGCRKKCLSILKTLRDRHLELPGQPLNNYHMKTLVSYECEKHPRESDWDESCLGDRLNGILLQLISCLQCRRCPHYFLPNLDLFQGKPHSALENAAKQTWRLAREILTNPKSLEKL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70299-1", "uniprot_id": "MB211_MOUSE", "id": "O70299-1", "name": "Putative nucleotidyltransferase MAB21L1", "aln": "------MIAAQAKLVYHLNKYYNEKCQARKAAIAKTIREVCKVVSDVLKEVEVQEPRFISSLNEMDNRYEGLEVISPTEFEVVLYLNQMGVFNFVDDGSLPGCAVLKLSDGRKRSMSLWVEFITASGYLSARKIRSRFQTLVAQAVDKCSYRDVVKMVADTSEVKLRIRDRYVVQITPAFKCTGIWPRSAAHWPLPHIPWPGPNRVAEVKAEGFNLLSKECHSLAGKQ---SSAESDAWVLQFAEAENRLQMGGCRKKCLSILKTLRDRHLELPGQPLNNYHMKTLVSYECEKHPRESDWDESCLGDRLNGILLQLISCLQCRRCPHYFLPNLDLFQGKPHSALENAAKQTWRLAREILTNPKSLEKL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13394-1", "uniprot_id": "MB211_HUMAN", "id": "Q13394-1", "name": "Putative nucleotidyltransferase MAB21L1", "aln": "------MIAAQAKLVYHLNKYYNEKCQARKAAIAKTIREVCKVVSDVLKEVEVQEPRFISSLNEMDNRYEGLEVISPTEFEVVLYLNQMGVFNFVDDGSLPGCAVLKLSDGRKRSMSLWVEFITASGYLSARKIRSRFQTLVAQAVDKCSYRDVVKMVADTSEVKLRIRDRYVVQITPAFKCTGIWPRSAAHWPLPHIPWPGPNRVAEVKAEGFNLLSKECHSLAGKQ---SSAESDAWVLQFAEAENRLQMGGCRKKCLSILKTLRDRHLELPGQPLNNYHMKTLVSYECEKHPRESDWDESCLGDRLNGILLQLISCLQCRRCPHYFLPNLDLFQGKPHSALENAAKQTWRLAREILTNPKSLEKL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NYB4-1", "uniprot_id": "MB211_DANRE", "id": "Q6NYB4-1", "name": "Putative nucleotidyltransferase MAB21L1", "aln": "------MIAAQAKLVYHLNKYYNEKCQSRKAAISKTIREVCKVVSDVLKEVEVQEPRFISSLNEMDNRFEGLEVISPTEFEVVLYLNQMGVFNFVDDGSLPGCAVLKLSDGRKRSMSLWVEFITASGYLSARKIRSRFQTLVAQAVDKCSYRDVVKMVADTSEVKLRIRDRYVVQITPAFKCTGIWPRSAAHWPLPHIPWPGPNRVAEVKAEGFNLLSKECYSLNGKQ---SSAESDAWVLQFAEAENRLLLGGCRKKCLSLLKTLRDRHLELPGQPLNNYHMKTLVSYECEKHPRESDWDENCLGDRLNGILLQLISCLQCRRCPHYFLPNLDLFQGKPHSALENAAKQTWRLAREILTNPKSLEKL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9Y106-1", "uniprot_id": "MB21L_DROME", "id": "Q9Y106-1", "name": "Protein mab-21-like", "aln": "MLVPPDMMAAQTRMVYQMNRFCTERVQARMYKTATAIREICKIVQDILKEVELQEPRFISSLVECNGRFEGVEVISPNEFEIVLYLNQMGVFNFVDDGTLPGCAVLKLSDGRKRSMSLWVEFITASGYLSSRKIRARFQTLVAQACDKSVYRDMVKMVGDTSEVKLRIRERFVVQITPAFKCSGIWPRSAAHWPVPHLPWPHPNIVAEVKTEGFDLLSKESVIMQNKNNNAASMEGDAWVLSFFEAENRLLQGGCRRRCLSMLKTLRDRHLDLPGNPISAYHLKNLLLYECEKHPRDFEWDEGCIADRINGIFLQLISCLQYRRCPHYFLPALDMFKGKSPSALEQAAKQVWRLTRELLTNANAFEKL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9U3W6-1", "uniprot_id": "MAB21_DROME", "id": "Q9U3W6-1", "name": "Protein mab-21", "aln": "MLVPSDMIAAQSKMVYQMNKYCADRVQVRKAQIHKQIQEVCRIVQDVLKEVEVQEPRFISSLNDYNGRFQGLEVISPTEFEIIIYLNQMGVLNFVDDGTLPGCAVLKLSDGRKRSMSLWVEFITASGYLSARKIRSRFQTLVAQACDKCAYRDIVKMIADTTEVKLRIRERIIVQITPAFKCAGLWPRSASHWPLPGIPWPHPNIVAEVKTEGFNMLSKECIALQGKN---SAMEGDAWVLSFTDAENRLLQGASRRRCLSILKTLRDRHLDLPGNPVTSYHLKTLLLYECEKHPREMEWEENCIADRINGIFLQLISCLQCRRCPHYFLPNMDLFKGKSPGALENAAKQVWRLTRIMLTNVRCLEEL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:***:::**::*:: :: * * . *:*:*::*.*:*****:********* : :.*::*:*****.***:::*******:******:*******************************:****:********* **. ***:***:.**:*******:* :*********:*:*****:***:* :*** ** *****:***::****. : .*: :: *.*****.* :***** *..*::***:*********:***:*:. **:*.*: ********: :*:*.*:.**:***:******** ********* :*:*:**. .***:****.***:* :*** ..:*:*", "identical_positions": 237, "similar_positions": 89, "identity": "64.4%" }, { "cls_id": "homologset.agr.MGI:1333774", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P0C2B9-1", "uniprot_id": "RM42_RAT", "id": "P0C2B9-1", "name": "Large ribosomal subunit protein mL42", "aln": "-MTAAVKWAVSHRTIWRHLFPIQNGAISSACHKSTYSSLPDDYNCKVELALTSDGRTIVCYHPSVDVPYEHTKPIPHPDLLHNNEETHEQILRTKLEG-NHKHLEQGPMIEQLSKVFFTTKHRWYPHGQYHRCRKKLNPPKDR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CPV3-1", "uniprot_id": "RM42_MOUSE", "id": "Q9CPV3-1", "name": "Large ribosomal subunit protein mL42", "aln": "-MAAAVKWAISNRTIWKHLLPIQNGALSSACHKSTYSSLPDDYNCQVDLALTADGRTIVCYHPSVDIPYEHTKPIPQPDLLHNNEETHEQILKAKLEVRKSKQLEQGPMIEQLSKVFYTTKHRWYPHGQYHNRRKKLNPPRDR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y6G3-1", "uniprot_id": "RM42_HUMAN", "id": "Q9Y6G3-1", "name": "Large ribosomal subunit protein mL42", "aln": "MAVAAVKWVMSKRTILKHLFPVQNGALYCVCHKSTYSPLPDDYNCNVELALTSDGRTIVCYHPSVDIPYEHTKPIPRPDPVHNNEETHDQVLKTRLEE-KVEHLEEGPMIEQLSKMFFTTKHRWYPHGRYHRCRKNLNPPKDR", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .*****.:*:*** :**:*:****: ..*******.*******:*:****:*************:*********:** :*******:*:*:::** : ::**:*********:*:**********:**. **:****:**", "identical_positions": 102, "similar_positions": 32, "identity": "71.33%" }, { "cls_id": "homologset.agr.MGI:1333776", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q75NT5-1", "uniprot_id": "AHRR_RAT", "id": "Q75NT5-1", "name": "Aryl hydrocarbon receptor repressor", "aln": "MMIPSGECTYAGRKRRK-PIQKRRLTMGTEKSNPSKRHRDRLNTELDHLASLLPFSPDIISKLDKLSVLRLSVSYLRVKSFFQALQETCVWSAPALSP---EDHSSR------GFPVQEGRLLLESLNGFALVVSAEGMIFYASATIVDYLGFHQTDVMHQNIYDYIHVDDRQDFCRQLHWAMDPPQVVFGQSPHADT-DNTVLGKLLRAQEGGKGLPSEYSAFLTRCFICRVRCLLDSTSGFLTMQFQGKLKFLFGQKKKTPSGTALPPRLSLFCIVAP-VLPSVTEMKMKSAFLKAKHRAD-IVVTMDSRAKAVTSLCESELH---------------PKLNYLAGRSNGENVISLFRGQTDRSHWTRALARSSCLCLRGGPD-LLDPKGTSGD----------------------------REEDDQKHILRRSPGARGQREMHKYSYGLETPVHLRHLDWSTEQRSQEGTTKLTRQPSKSEP-STCLVPHGSCVPYPGSQGMFSASNMASFRESLDHPTGTYCSQMN------------------------------------------RPLPDIHQGQVDPSTCHIPQGSLGSRIPLSGMQCFTARGFSTEDAKLPSLPVNIGTPC--------------------------------------------------------NPVLSLEVPIKME------------------------NESGSQDIVEASTTSCVWLGTGDMT-RRHLVGFPARMHLKTE---------------PDYRQQVCTPHRGHGILGTNPHSRDTVGSCREHAPLYSAHCTCLSP-------EPPHHLFMCSHSESQHPSLDQD--CRAPIVKREPLDS-----------------------PSWAAPG-HVTVPRMFPKNASITVIPSKGSDGIFLP--------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3U1U7-1", "uniprot_id": "AHRR_MOUSE", "id": "Q3U1U7-1", "name": "Aryl hydrocarbon receptor repressor", "aln": "MMIPSGECTYAGRKRRK-PIQKRRLTMGAEKSNPSKRHRDRLNTELDHLASLLPFSPDIISKLDKLSVLRLSVSYLRVKSFFQALQETCVWSAPALSP---EEHSYR------GFPVQEGRLLLESLNGFALVVSAEGMIFYASATIVDYLGFHQTDVMHQNIYDYIHVDDRQDFCRQLHWAMDPPQVVFGQSPHADT-DNTVLGKLLRAQEGGKGLPSEYSAFLTRCFICRVRCLLDSTSGFLTMQFQGKLKFLFGQKKKTPSGTALPPRLSLFCIVAP-VLPSVTEMKMKSTFLKAKHRAD-IVVTMDSRAKAVTSLCESELH---------------PKLNYLAGKSNGENGISLFRGQTDRSHWARALARSSCLCLRGGPD-LLDPKGTSGD----------------------------REEEDQKHILRRSPGAWGQREMHKYSYGLETPVHLRHLNWSTEQRSQESTTKLTRQPSKNEP-STCLVPHGSCVPYPGSQGMLSASNMASFRDSLDHPTGAYCSQMN------------------------------------------RPLSDIHQGQVDPSTCHISQGSLGSRIPLTGMQRFTARGFSTEDAKLPSLPVTIGTPC--------------------------------------------------------NPVLSLDVPIKME------------------------NESGSQDIVEASTTSCLWLGTSDMA-RGHLVGFPARMHLKTE---------------PDYRQQACTPHLGHGMLGTNPYSRDTVGSCREHAPLYSAHCTCLDP-------EPPHHFFMCSHSESQHPSLDQD--CRAPIVKREPLDS-----------------------PSWAAPG-QVTVPRMFPKSASKTVIPSKGSDGIFLP--------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A9YTQ3-1", "uniprot_id": "AHRR_HUMAN", "id": "A9YTQ3-1", "name": "Aryl hydrocarbon receptor repressor", "aln": "-MIPPGECTYAGRKRRR-PLQKQRPAVGAEKSNPSKRHRDRLNAELDHLASLLPFPPDIISKLDKLSVLRLSVSYLRVKSFFQVVQEQSSRQPAAGAPSPGDSCPLA------GSAVLEGRLLLESLNGFALVVSAEGTIFYASATIVDYLGFHQTDVMHQNIYDYIHVDDRQDFCRQLHWAMDPPQVVFGQPPPLETGDDAILGRLLRAQEWGTGTPTEYSAFLTRCFICRVRCLLDSTSGFLTMQFQGKLKFLFGQKKKAPSGAMLPPRLSLFCIAAPVLLPSAAEMKMRSALLRAKPRAD-TAATADAKVKATTSLCESELH---------------GKPNYSAGRSSRESGVLVLREQTDAGRWAQVPARAPCLCLRGGPDLVLDPKGGSGD----------------------------REEE-QHRMLSRASGVTGRR---------ETPGPTKPLPWTAGKHSEDG-ARPRLQPSKNDPPSLRPMPRGSCLPCPCVQGTFRNSPIS---HPPSPSPSAYSSRTS------------------------------------------RPMRDVGEDQVHPPLCHFPQRSLQHQLPQPGAQRFATRGYPMEDMKLQGVPMPPGDLC--------------------------------------------------------GPTLLLDVSIKME------------------------KDSGCEGAADGCVPSQVWLGASD---RSHPATFPTRMHLKTE---------------PDSRQQVYISHLGHGVRGAQPHGRATAGRSRELTPFHPAHCACLEPTDGLPQSEPPHQLCARGRGE-QSCTCRAA--EAAPVVKREPLDS-----------------------PQWATHS-QGMVPGMLPKSALATLVPPQASGCTFLP--------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32U0D7-1", "uniprot_id": "A0AB32U0D7_DANRE", "id": "A0AB32U0D7-1", "name": "", "aln": "-MIPPGDCLYAGRKRRK-PVQKQKPEKADQKSNPSKRHRDRLNAELDRLASLLPFSAEVITKLDKLSVLRLSVSFLRVKSFFQAVQEKENHSADVSPT---ETRKEV------QPCVVESDLLLQSLSGFALVVSSDGIIFYASSTIIDYLGFHQTDVMHQKVFDYIHVDERQEFRKQIHWAMNP-----GQQ---DTDEDVVTAHLYSAEQ-PDGVSPELTPFLTRCFIARMRCLLDSTSGFLNMQFQGSLKFLQGQRRRTLSGALLPPQLALFCVAVPLVLPSITELRMKSVTVKCKNRSS-GCS--EKRQRAPRGSYDSEDE---------------LRYNWMSTFSQDAS-------------WAYSRKYR----------------GDACK----------------------------TQDEPLNSHVSTSVSS----------------------KLQTDDASWDARCPVALRTDSNEN----------------------------------YQPGSFQKHNY------------------------------------------SVKLRIG------CNSHLQKYEVDD-----------EKRYMMQNEAFNTLP---------------------------------------------------------------------EAAIKTE------------------------QDSDSENGCNAYG--MLWR--------------PDYTQVKTE---------------PEYYDYCSFYQKGKTTVSPYTNGHHKYLCAGVSRPRKCVLYKDLNHSDVPIGNQDGYMFTNEHKNNMQRLAYEFRGHNRVHIIKQEPDDS-----------------------PVWCPEVIQGHVQHNIPANCTVSNVVLKGNPYVHMQ--------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E1JIM6-1", "uniprot_id": "E1JIM6_DROME", "id": "E1JIM6-1", "name": "", "aln": "-MSQLGTVYATKRRRRNGKSLKPPPKDGVTKSNPSKRHRERLNAELDLLASLLPFEQNILSKLDRLSILRLSVSYLRTKSYFQVVMHKDKEDNGVLPHIHAHDGYRTRELGAFEHGLLDGDMFLQALNGFLMILTCEGEVFFATHSIESYLGFHQSDIVHQSVYELVHSEDREELQRQLLW-------------------NSFLPADMSSMQLAETLAPDKALYLERSFTVRFRCLLDNTSGFLRLDIRGRIKVLHGQNRKTEE-----PPLALFAYCTPFGPPSLLEIPHKENMFKSKHKLDFSLVSMDQRGKHILGYADAELVNMGGYDLVHYDDLAYVASAHQELLKTGASGMIAYRYQKKDGEWQWLQTSSRLVYKNSKPDFVICTHRQLMDEEGHDLLGKRTMDFKVSYLDTGLASTYFSEADQLVVPPSTSPTAHALPPPVTPTRPNRRYKTQLRDFLSTCRSKRKLQQQNQPQTQQTSPLGGQVGSPAPAVAVEYLPDPAAAVAAAYSNLNPMYTTSPYASAADNLYMGSSMPANAFYPVSENLFHQYRLQGAVGGYYTDYPHSGAPASAYVANGFLSYDGYAIASKADEKWQETGKYYSGYSSGYGSPTSTPQQIPLKTPKSSPQVMEVISCSSDGPSPVGGATPNGVGSVTPKVELAGTTAAAAAGQDPYERQTVLMWGTTHSSGVPLNSHGGRTGAGNPASPQRSTPLGNGLGYASANNNNNDLEPATAAKWNGTKELPGKSGSASTPESYQMQHDDSGLYSASSHTTSPQQQQQQQLQQSQRGVGSNVSAPSSSLTSTGTDQQAVHPSSCHQQQQQQQQQHHHAHPHPHSHHHHHHHHHHETAHQHSSEIILTTHHQQQSQQQQQSLAGYPLHHQLVGVGSGSPPPQPPVALSRSPTTLPAVSSLLNGSASAGGASDIPYQQLAIVSAPLVICAEEVGGGVSSIGRKSSKQQQSLQHLQQQQSLQQQQHAIYQQQHHHSQHHPHHQLLYPANITAHTALAYAPPTAGGAYADGSPLLSFSEVTNTLLNQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * : *:**. * . *********:***:*** ******* ::::***:**:******:**.**:**.: . . . . . : :. ::*::*.** ::::.:* :*:*: :* .******:*::**.::: :* ::*::: :*: * : . : : ..: : :* *.* *.*****.***** ::::* :*.* **.::: . * *:**. .* ** *: :. .:.* : . : : : . ::* . . * . : : : : . . :..... ...: . : : . : :* ..:: . .:. :. * * ::: : : : : * . . . . . : : . : : .:. :* * . :* . ... : ", "identical_positions": 103, "similar_positions": 159, "identity": "9.9%" }, { "cls_id": "homologset.agr.MGI:1333777", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R2N1-1", "uniprot_id": "AQP3_MOUSE", "id": "Q8R2N1-1", "name": "Aquaporin-3", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGRQKELMNRCGEMLHIRYRLLRQALAECLGTLILVMFGCGSVAQVVLS------------------------------------RGTHGGFLTINLAFGFAVTLGILVAG--QVSGAHLNPAVTFAMCFLAREPWIKLPIYALAQTLGAFLGAGIVFGLYYDAIWAFANNELFVSGPNGTAGIFATYPSGHLDMVNGFFDQFIGTAALIVCVLAIVDPYNNPVPRGLEAFTVGLVVLVIGTSMGFNSGYAVNPARDFGPRLFTALAGWGSEVFTTGRHWW-WVPIVSPLLGSIAGVFVYQLMIGCHLEQPP------------------------------------PSTEEENVKLAHMKHKEQI---------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P47862-1", "uniprot_id": "AQP3_RAT", "id": "P47862-1", "name": "Aquaporin-3", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGRQKELMNRCGEMLHIRYRLLRQALAECLGTLILVMFGCGSVAQVVLS------------------------------------RGTHGGFLTINLAFGFAVTLAILVAG--QVSGAHLNPAVTFAMCFLAREPWIKLPIYTLAQTLGAFLGAGIVFGLYYDAIWAFAGNELVVSGPNGTAGIFATYPSGHLDMVNGFFDQFIGTAALIVCVLAIVDPYNNPVPRGLEAFTVGLVVLVIGTSMGFNSGYAVNPARDFGPRLFTALAGWGSEVFTTGQNWW-WVPIVSPLLGSIGGVFVYQLMIGCHLEQPP------------------------------------PSTEAENVKLAHMKHKEQI---------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q92482-1", "uniprot_id": "AQP3_HUMAN", "id": "Q92482-1", "name": "Aquaporin-3", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGRQKELVSRCGEMLHIRYRLLRQALAECLGTLILVMFGCGSVAQVVLS------------------------------------RGTHGGFLTINLAFGFAVTLGILIAG--QVSGAHLNPAVTFAMCFLAREPWIKLPIYTLAQTLGAFLGAGIVFGLYYDAIWHFADNQLFVSGPNGTAGIFATYPSGHLDMINGFFDQFIGTASLIVCVLAIVDPYNNPVPRGLEAFTVGLVVLVIGTSMGFNSGYAVNPARDFGPRLFTALAGWGSAVFTTGQHWW-WVPIVSPLLGSIAGVFVYQLMIGCHLEQPP------------------------------------PSNEEENVKLAHVKHKEQI---------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P43549-1", "uniprot_id": "AQY3_YEAST", "id": "P43549-1", "name": "Aquaglycerol porin AQY3", "aln": "MSYESGRSSSSSESTRPPTLKEEPNGKIAWEESVKKSRENNENDSTLLRRKLGETRKAIETGGSSRNKLSALTPLKKVVDERKDSVQPQVPSMGFTYSLPNLKTLNSFSDAEQARIMQDYLSRGVNQGNSNNYVDPLYRQLNPTMGSSRNRPVWSLNQPLPHVLDRGLAAKMIQKNMDARSRASSRRGSTDISRGGSTTSVKDWKRLLRGAAPGKKLGDIEAQTQRDNTVGADVKPTKLEPENPQKPSNTHIENVSRKKKRTSHNVNFSLGDESYASSIADAESRKLKNMQTLDGSTPVYTKLPEELIEEENKSTSALDGNEIGASEDEDADIMTFPNFWAKIRY-HMREPFAEFLGTLVLVIFGVGGNLQATVT------------------------------------KGSGGSYESLSFAWGFGCMLGVYVAG--GISGGHINPAVTISMAIFRKFPWKKVPVYIVAQIIGAYFGGAMAYGYFWSSITEFEGGPHIRTTATG--ACLFTDPKSYVTWRNAFFDEFIGASILVGCLMALLDDSNAPPGNGMTALIIGFLVAAIGMALGYQTSFTINPARDLGPRIFASMIGYGPHAFHLTHWWWTWGAWGGPIAGGIAGALIYDIFIFTGCESPVNY----------------------------------PDNGYIENRVGKLLHAEFHQNDGTVSDESGVNSNSNTGSKKSVPTSS-----------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P23900-1", "uniprot_id": "FPS1_YEAST", "id": "P23900-1", "name": "Glycerol uptake/efflux facilitator protein", "aln": "-----------------------------------------------MSNPQKALNDFLSSESVHTHDSSRKQSNKQSSDEGRSSSQPSHHHSGGTNNNNNNNNNNNNSNNNNN----------GNDGGNDDDYDYEMQDYRPSPQSARPTPTYVPQYSVESGTAFPIQEVIPSAYINTQDINHKDNGPPSASSNRAFR------------------------PRGQTTVSANVLNIEDFYKNADDAHTIPESHLSRRRSRSRATSN--AGHSANTGATNGRTTGAQTNMESNESPRNVPIMVKPKTLYQNPQTP------------TVLPSTYHPINKWSSVKNTYLKEFLAEFMGTMVMIIFGSAVVCQVNVAGKIQQDNFNVALDNLNVTGSSAETIDAMKSLTSLVSSVAGGTFDDVALGWAAAVVMGYFCAGGSAISGAHLNPSITLANLVYRGFPLKKVPYYFAGQLIGAFTGALILFIWYKRVLQEAYSDWWMNESVAG---MFCVFPKPYLSSGRQFFSEFLCGAMLQAGTFALTDPYTCLS-SDVFPLMMFILIFIINASMAYQTGTAMNLARDLGPRLALYAVGFDHKMLWVHHHHFFWVPMVGPFIGALMGGLVYDVCIYQGHESPVNWSLPVYKEMIMRAWFRRPGWKKRNRARRTSDLSDFSYNNDDDEEFGERMALQKTKTKSSISDNENEAGEKKVQFKSVQRGKRTFGGIPTILEEEDSIETASLGATTTDSIGLSDTSSEDSHYGNAKKVT", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . :: ::: :** :**:::::** . *. :: : * : : :.:. . :. ** :**.*:**::*:: . * *:* * .* :**: *. : : : : .. . * : . *. :: . **.:*: : * :*: * . .: .: : ::: *. ::.:::. ::* ***:***: *:. : : : * . .*: *.: * ::*:: * *.* . . : .... : ", "identical_positions": 49, "similar_positions": 104, "identity": "6.38%" }, { "cls_id": "homologset.agr.MGI:1333778", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62252-1", "uniprot_id": "SP17_MOUSE", "id": "Q62252-1", "name": "Sperm surface protein Sp17", "aln": "MSIPFSNTHYRIPQGFGNLLEGLTREILREQPDNIPAFAAAYFENLLEKREKTSFDPAEWGAKVEDRFYNNHAFK------------------------------------------------------------EQE--------QVEKCE------------------------------------------------------------------------------QELAKS-------------------------------------------------------------------------------------------------------------------------------------------------------SGREET--------------------------PVTPFEES----------------------------------------------------------------------------------------------------TEEEREQEE---------------------------------------------------AAALKIQSLFRGHVAREEVKKMKSDKNENLKEEADN----------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15506-1", "uniprot_id": "SP17_HUMAN", "id": "Q15506-1", "name": "Sperm surface protein Sp17", "aln": "MSIPFSNTHYRIPQGFGNLLEGLTREILREQPDNIPAFAAAYFESLLEKREKTNFDPAEWGSKVEDRFYNNHAFE------------------------------------------------------------EQE--------PPEKSD------------------------------------------------------------------------------PKQEESQ-----------------------------------------------------------------------------------------------------------------------------------------------------ISGKEEE--------------------------TSVTILDS----------------------------------------------------------------------------------------------------SEEDKEKEE---------------------------------------------------VAAVKIQAAFRGHIAREEAKKMKTNSLQNEEKEENK----------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32T576-1", "uniprot_id": "A0AB32T576_DANRE", "id": "A0AB32T576-1", "name": "", "aln": "MAVPFSNTHLRIPRGFGNLLEGLTREVLREQPEDIATFAAVYFTELLKAREESGLDPAEWGAKLEDRFYNNHSFKGTSLQGNIISPKINTRINAESSSETLGNNETQLSALKDLDTDNSVGSEVNLDKKFDEESGEKERGHAEDILPAETADGDKCAEELKDTNEIPGETSEVAKEEVDVDICRSELEPTPLPSFGGHANVDVCAEEINLQSESSKSKEELVSPKPLFLNKDQSESQDEIHSHTEQDASKQANEMSDHGDDDDAEDPEEEVSEIADNLLEDIDPEEKSTEQVYAEESTESTIEKYITESVAGQESEDAINEDQEETNYEYTSTNDFVEDAGDSTSDINSRSLMEMKDTHVDYSDEIHDSKSEVVDVLDEVHHQCDTRTGEEEAENSSDEENTSKILDALNEEDFLETPKPVSQMNDSEAEASNEILNADAFEKDLNTENVNEGSDLDSDGFEAEEMDLDISNVLQPNEEKTEDEGNHDPEPEEDAFSEAEQANPEPLENETVVVNEELFESQEQTENTENDVDQEDQLEEQRDKIQEMTLESENLENTDISEPKEECSQPQEEEDIMDIPLDDPEANKAAAKIQAGFRGHMTRKKMKPGEKPGEEEEQTRSGHLMWKVGQAMRMKVSFQPPAGPKYLSFSCAALLYPTSVPNLGLSRATSTQFSVAKHFMYESVIFILRCICIAKTRLCSVFTRTKIKDRMRSTHILPKSINKCQIVVNASTKCFYFVCLA", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*::****** ***:************:*****::*.:***.** .**: **::.:******:*:********:*: *:* *..: . :* :*.** . : :* :*:: ::*: ** ***: ****::*:: * :. :: : . .: ", "identical_positions": 74, "similar_positions": 49, "identity": "9.99%" }, { "cls_id": "homologset.agr.MGI:1333780", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CZX8-1", "uniprot_id": "RS19_MOUSE", "id": "Q9CZX8-1", "name": "Small ribosomal subunit protein eS19", "aln": "MPGVTVKDVNQQEFVRALAAFLKKSGKLKVPEWVDTVKLAKHKELAPYDEN-WFYTRAASTARHLYLRGGAGVGSMTKIYGGRQRNGVRPSHFSRGSKSVARRVLQALEGLKMVEKDQDGGRKLTPQGQRDLDRIAGQVAAANKKH-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P17074-1", "uniprot_id": "RS19_RAT", "id": "P17074-1", "name": "Small ribosomal subunit protein eS19", "aln": "MPGVTVKDVNQQEFVRALAAFLKKSGKLKVPEWVDTVKLAKHKELAPYDEN-WFYTRAASTARHLYLRGGAGVGSMTKIYGGRQRNGVRPSHFSRGSKSVARRVLQALEGLKMVEKDQDGGRKLTPQGQRDLDRIAGQVAAANKKH-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P39019-1", "uniprot_id": "RS19_HUMAN", "id": "P39019-1", "name": "Small ribosomal subunit protein eS19", "aln": "MPGVTVKDVNQQEFVRALAAFLKKSGKLKVPEWVDTVKLAKHKELAPYDEN-WFYTRAASTARHLYLRGGAGVGSMTKIYGGRQRNGVMPSHFSRGSKSVARRVLQALEGLKMVEKDQDGGRKLTPQGQRDLDRIAGQVAAANKKH-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZSH6-1", "uniprot_id": "D3ZSH6_RAT", "id": "D3ZSH6-1", "name": "", "aln": "--GVTVKDFNQQEFIRALAVFLKKSGKLKVPEWVDTVKLVKHKELAPYDEN-WFYTRAASTARHLYLRGGAGVGSVTKIYGGWQRNSVRPSHFSRGSKSVARRVLQASEGLKMVEKDQDGDHKLTPQGQRDLGSPD---------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7KS38-1", "uniprot_id": "RS19B_DROME", "id": "Q7KS38-1", "name": "Small ribosomal subunit protein eS19B", "aln": "MPGVTVKEIDQHVLTKNMAAFLKKSGKIFVPEQAVYMKTGKFKETAPTDDD-WFYTRCASIMRHLYLRSPAGVGAFTKVYSGRKRNGVRPSKHCRSSDGCIRKALQALEAANMVERHPDGGRKLTPQGQRNLDRIANKIVAKQRERSAPVSMIITT-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39018-1", "uniprot_id": "RS19A_DROME", "id": "P39018-1", "name": "Small ribosomal subunit protein eS19A", "aln": "MPGVTVKDIDQHAVTKAVAVFLKKTGKLKVPDQMDIVKTAKFKELAPYDPD-WFYVRCASILRHLYHRSPAGVGSITKIYGGRKRNGVHPSHFCRAADGAARKALQALEHARLVEKHPDGGRKLSSIGQRDLDRIANQIVFKQRDAAKQTGPIVISK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P07280-1", "uniprot_id": "RS19A_YEAST", "id": "P07280-1", "name": "Small ribosomal subunit protein eS19A", "aln": "MPGVSVRDVAAQDFINAYASFLQRQGKLEVPGYVDIVKTSSGNEMPPQDAEGWFYKRAASVARHIYMRKQVGVGKLNKLYGGAKSRGVRPYKHIDASGSINRKVLQALEKIGIVEISPKGGRRISENGQRDLDRIAAQTLEEDE-------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P07281-1", "uniprot_id": "RS19B_YEAST", "id": "P07281-1", "name": "Small ribosomal subunit protein eS19B", "aln": "MAGVSVRDVAAQDFINAYASFLQRQGKLEVPGYVDIVKTSSGNEMPPQDAEGWFYKRAASVARHIYMRKQVGVGKLNKLYGGAKSRGVRPYKHIDASGSINRKVLQALEKIGIVEISPKGGRRISENGQRDLDRIAAQTLEEDE-------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **:*::. : . . * **:: **: ** :* . :* .* * : *** *.** **:* * .*** ..*:*.* : ..* * :. .: . *:.*** * :** .*.:::: ***:*. ", "identical_positions": 44, "similar_positions": 41, "identity": "28.03%" }, { "cls_id": "homologset.agr.MGI:1333782", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5FVH2-1", "uniprot_id": "PLD3_RAT", "id": "Q5FVH2-1", "name": "5'-3' exonuclease PLD3", "aln": "MKPKLMYQELKVPVEEP---AGELPMNEIEAWKAAEKKARWVLLVLILAVVGFGALMTQLFLWEYGDLHLFGPNQHP-APCYDPCEAVLVESIPEGLEFPNATTSNPSTSQAWLGLLAGAHSSLDIASFYWTLTNNDTH-TQEPSAQQGEEVLQQLQALAPRG-----VKVRIAVSKPNGP--LADLQSLLQSG-AQVRMVDMQKLT-HGVLHTKFWVVDQTHFYLGSANMDWRSLTQVKELGVVMYNCSCLARDLTKIFEAYWFLGQAGSSIPSTWPRPFDTRYNQETPMEICLNG-TPALAYLASAPPPLCPGGRTPDLKALLSVVDNARSFIYIAVMNYLPTMEFSHPRRFWPAIDDGLRRAAYERGVKVRLLISCWGHSEPSMRSFLLSLAALRDNHTHSDIQVKLFVVPADEAQARIPYARVNHNKYMVTERTTYIGTSNWSGSYFTETAGTSLLVTQNGHGG----LRSQLEAVFLRDWESPYSHNLDTSADSVGNACRLL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35405-1", "uniprot_id": "PLD3_MOUSE", "id": "O35405-1", "name": "5'-3' exonuclease PLD3", "aln": "MKPKLMYQELKVPVEEP---AGELPLNEIEAWKAAEKKARWVLLVLILAVVGFGALMTQLFLWEYGDLHLFGPNQRP-APCYDPCEAVLVESIPEGLEFPNATTSNPSTSQAWLGLLAGAHSSLDIASFYWTLTNNDTH-TQEPSAQQGEEVLQQLQALAPRG-----VKVRIAVSKPNGP--LADLQSLLQSG-AQVRMVDMQKLT-HGVLHTKFWVVDQTHFYLGSANMDWRSLTQVKELGVVMYNCSCLARDLTKIFEAYWFLGQAGSSIPSTWPRSFDTRYNQETPMEICLNG-TPALAYLASAPPPLCPSGRTPDLKALLNVVDSARSFIYIAVMNYLPTMEFSHPRRFWPAIDDGLRRAAYERGVKVRLLISCWGHSDPSMRSFLLSLAALHDNHTHSDIQVKLFVVPTDESQARIPYARVNHNKYMVTERASYIGTSNWSGSYFTETAGTSLLVTQNGHGG----LRSQLEAVFLRDWESPYSHDLDTSANSVGNACRLL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IV08-1", "uniprot_id": "PLD3_HUMAN", "id": "Q8IV08-1", "name": "5'-3' exonuclease PLD3", "aln": "MKPKLMYQELKVPAEEP---ANELPMNEIEAWKAAEKKARWVLLVLILAVVGFGALMTQLFLWEYGDLHLFGPNQRP-APCYDPCEAVLVESIPEGLDFPNASTGNPSTSQAWLGLLAGAHSSLDIASFYWTLTNNDTH-TQEPSAQQGEEVLRQLQTLAPKG-----VNVRIAVSKPSGPQPQADLQALLQSG-AQVRMVDMQKLT-HGVLHTKFWVVDQTHFYLGSANMDWRSLTQVKELGVVMYNCSCLARDLTKIFEAYWFLGQAGSSIPSTWPRFYDTRYNQETPMEICLNG-TPALAYLASAPPPLCPSGRTPDLKALLNVVDNARSFIYVAVMNYLPTLEFSHPHRFWPAIDDGLRRATYERGVKVRLLISCWGHSEPSMRAFLLSLAALRDNHTHSDIQVKLFVVPADEAQARIPYARVNHNKYMVTERATYIGTSNWSGNYFTETAGTSLLVTQNGRGG----LRSQLEAIFLRDWDSPYSHDLDTSADSVGNACRLL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1L8A0-1", "uniprot_id": "Q1L8A0_DANRE", "id": "Q1L8A0-1", "name": "5'-3' exonuclease PLD3", "aln": "MKSDIPYEKM-VDVELS---RGEGHHGSQKYYRCLIVLT--CITTVLLILLSLQTLLVPMAKSSSTKSSVQQERVLIRETCTDPCRIVLVESIPEGMVFN--SSVHQSIYDAWLNLISATQSSLDIASFYWTLTNSDTH-TQEPTANQGQQILKKLGQLSSK------AYVRIAVDKPADKKPMEDINFLSSYG-ADVRMVNMRELT-TGVLHTKFWIVDKKHIYIGSANMDWRSLTQVKELGAVVYDCSCLAEDLGKIFEAYWYLNQT-KTVPAHWPNKYSTLYNKDTPMQLSLNG-TSASVYLSSSPPSLCAEGRTPDLQSILDVIANAQQFVYIAVMNYLPTMEFSRSKRYWMDIDTELRRVAYERRIRVRLLISCWNSTKPIMFPFLRSLASLQDTN-QLDIQVRIFTVPSDAQQKKIPFARVNHNKYMVTDQVAYIGTSNWSGDYFVNTAGSALVVNQTSASASS-TVQEQLQAVFERDWESAYSTDINHRSNRK-DIC---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VIF2-1", "uniprot_id": "Q9VIF2_DROME", "id": "Q9VIF2-1", "name": "", "aln": "MPEYKKLEDQESDVENANRTTVQNTATVQDAGEGQRQAAGQQAGQMVTVSLFMLLFLGSSYFQPRPRLHQYKGGRGHGLLEKFDCNIQLVESIPIGLTYPDGSPRFLSTYEAWLELLESATTSLDIASFYWTLKAEDTPGVSDNSTRPGEDVFARLLANGNGGSRSPRIKIRIAQSEPSSGTPNLNTKLLASAGAAEVVSISFPKYFGSGVLHTKLWVVDNKHFYLGSANMDWRALTQVKEMGVLVQNCPELTHDVAKIFGEYWYLGNSESSRIPDWDWRYATSYNLKHPMQLSVNKNTSIEGFLSSSPPPLSPSGRTDDLNAILNTINTAITYVNIAVMDYYPLIIYEKNHHYWPFIDDALRKAAVERGVAVKLLISWWKHSNPSEDRYLRSLQDLASKEDKIDIQIRRFIVPTDSSQEKIPFGRVNHNKYMVTDRVAYIGTSNWSGDYFTDTAGIGLVLSETFETETTNTLRSDLRNVFERDWNSKYATPLV-------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :. .* . : . . : :: : : :: *. ****** *: : :. * :*** *: .: :***********. .** ..: ::. *:::: :* . :*** .:* . : : * . * *:* :.: : ******:*:**:.*:*:********:******:*.:: :*. *:.*: *** **:*.:: .: . * : * ** . **::.:* *. :*:*:**.*.. *** **:::*..: .* :: :***:* * : :.: :::* ** **:.: ** : *:**** * :.* :* ** * ... : ***:: * **:* * :**:.**********::.:*********.**.:*** .*::.:. ::.:*. :* ***:* *: : ", "identical_positions": 158, "similar_positions": 144, "identity": "31.16%" }, { "cls_id": "homologset.agr.MGI:1333783", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JK72-1", "uniprot_id": "CCS_RAT", "id": "Q9JK72-1", "name": "Copper chaperone for superoxide dismutase", "aln": "------------------MASKSGDGGTMCALEFTVQMS--CQSCVDAVHKTLKGAAGVQNVEVQLENQMVLVQTTLPSQEVQALLESTGRQAVLKGMGSSQLKNLGAAVAIME------GSGTVQGVVRFLQLSSEL---CLIEGTIDGL-EPGLHGLHVHQYGDLTKDCSSCGDHFNPDGASHGGPQD--TDRHRGDLGNVHAEASGRATFRIEDKQLKVWDVIGRSLVVDEGEDDLGRGGHPLSKVTGNSGKRLACGIIARSAGLFQNPKQICSCDGLTIWEERGRPIAGQGRKDSAQPPAHL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WU84-1", "uniprot_id": "CCS_MOUSE", "id": "Q9WU84-1", "name": "Copper chaperone for superoxide dismutase", "aln": "------------------MASKSGDGGTVCALEFAVQMS--CQSCVDAVHKTLKGVAGVQNVDVQLENQMVLVQTTLPSQEVQALLESTGRQAVLKGMGSSQLQNLGAAVAILE------GCGSIQGVVRFLQLSSEL---CLIEGTIDGL-EPGLHGLHVHQYGDLTRDCNSCGDHFNPDGASHGGPQD--TDRHRGDLGNVRAEAGGRATFRIEDKQLKVWDVIGRSLVIDEGEDDLGRGGHPLSKITGNSGKRLACGIIARSAGLFQNPKQICSCDGLTIWEERGRPIAGQGRKDSAQPPAHL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14618-1", "uniprot_id": "CCS_HUMAN", "id": "O14618-1", "name": "Copper chaperone for superoxide dismutase", "aln": "------------------MASDSGNQGTLCTLEFAVQMT--CQSCVDAVRKSLQGVAGVQDVEVHLEDQMVLVHTTLPSQEVQALLEGTGRQAVLKGMGSGQLQNLGAAVAILG------GPGTVQGVVRFLQLTPER---CLIEGTIDGL-EPGLHGLHVHQYGDLTNNCNSCGNHFNPDGASHGGPQD--SDRHRGDLGNVRADADGRAIFRMEDEQLKVWDVIGRSLIIDEGEDDLGRGGHPLSKITGNSGERLACGIIARSAGLFQNPKQICSCDGLTIWEERGRPIAGKGRKESAQPPAHL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58FYM8-1", "uniprot_id": "A0AC58FYM8_DANRE", "id": "A0AC58FYM8-1", "name": "Copper chaperone for superoxide dismutase", "aln": "MRFHTLIWINDFDDVTPHFSLSSDFQDLRFLLEFAVQMS--CDSCVNAVKAVLEKDPGVQSVQVNLSKEEVLVETALTSLQVQTLIESTGRRAVLKGMGGSDSD-LGAAVAMLS------GAGLVQGVVRFLQLSQDR---CLIDGTIDGL-SPGAHGLHVHELGDLTQDCRSCGDHFNPFRKQHGAPQD--SDRHVGDLGNISAGPDGRASFRLEDSQIKVWDVIGRSLVVDSGEDDLGRGNHPLSKTTGNSGERLACGIIARSAGLFQNPKQICACDGVTLWEERDRPIAGRGRRVETHT-SHL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E1JH26-1", "uniprot_id": "CCS_DROME", "id": "E1JH26-1", "name": "Copper chaperone for superoxide dismutase", "aln": "------------------MSS--------IKIEFAVQMRRGDESYAGALRSALDG---VGQVEIDTQEGRVIIQTQRPWSEIQDKIEATGVRAVLSGFGGQSAVALINTTGSVV------DKTPIQGVVRFTTITADKKPGVVVDGVVDGL-SPGLHGLHIHESGDTSAGCSSVGEHYNPRQSPHGSPAAGAEERHAGDLGNIRADENGRATFRFVDPVLEVWDIIGRAVVLTANADDLGRGGNDQSLIDGNSGERIACGIIARSAGILENFKRICACDGVTLWDERNKPLAGKERSQKL------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40202-1", "uniprot_id": "CCS1_YEAST", "id": "P40202-1", "name": "Superoxide dismutase 1 copper chaperone", "aln": "------------------MTTN-----DTYEATYAIPMH--CENCVNDIKACLKNVPGINSLNFDIEQQIMSVESSVAPSTIINTLRNCGKDAIIRGAGKPNSSAVAILETFQKYTIDQKKDTAVRGLARIVQVGENK---TLFDITVNGVPEAGNYHASIHEKGDVSKGVESTGKVWHKFDEPIECFNE-------SDLG-----KNLYSGKTFLSAPLPTWQLIGRSFVISKS---LNHPENEPSSVKDYS----FLGVIARSAGVWENNKQVCACTGKTVWEERKDALANNIK----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: ::: * :. .. :: *. : .::.. .. : :.: . : :. * *:: * * . : ::*:.*: : : :.: .::*: ..* : :*: ** : . * *. :: .*** . : : . : .*::***:.:: . *.: : * . * *:******: :* *::*:* * *:*:** .:*.. : ", "identical_positions": 42, "similar_positions": 87, "identity": "13.73%" }, { "cls_id": "homologset.agr.MGI:1333784", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6G4R8-1", "uniprot_id": "A0A8I6G4R8_RAT", "id": "A0A8I6G4R8-1", "name": "Histone deacetylase", "aln": "-MNSPNES-----------------ADGMSGREPSLEILPRTPLHSIPVAVEVKPVLPAAMPSSMGGGG---GGSPSPVELRG----ALAGPMDPALREQQLQQELLVLKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHLKQQQEMLAAK---------RQQELEQQRQREQQRQEELEKQRLEQQLLILRNKEKSKESAIASTEVKLRLQEFLLSKSKEPTPGGLNHSLPQHPKCWGAHHASLDQSSPPQSGPPGTPPSYKLP-LLGPYDSRDDFPLRKTASEPNLKVRSRLKQKVAERRS---SPLLRRKDGTVISTFKKRAVEITGTGPGVSSVCNSAPGSGPSSPNSSHSTIAENGFTGSVPN---IPTEMLP-QHRALPLDSSPNQFSLYTSPSLPNISLGLQATVTVTNSHLTASPKLSTQQEAERQALQSLRQGSTLTGKFMSTSSIPGCLLGVALE------------------------------GDTSPHGHASLLQHVLLLEQARQQSTLIAVPLHGQSPLVTG-----------ERVATSMRTVGKLP-----------------------------------------------------RHRPLSRTQSSPLPQ----SPQALQQLVMQQQHQQFLEKQKQQQMQLGKILTKTGELSRQPTTHPEETEEELTEQQEALLGEG---------------------------------------------ALTMPREGSTESESTQEDLEEEEDEEE-DEE-DCIQVKDEDGESGPDEGADLEESSAGYKKLFADAQQLQPLQVYQAPLSLAT-------------VPHQALGRTQSSPAAPGSMKSPTDHPTVVKHLFTTGVVYDTFMLKHQCMCGNTHVHPEHAGRIQSIWSRLQETGLLSKCERIRGRKATLDEIQTVHSEYHTLLYGTSPLNRQKLDSKKLLGPISQKMYAMLPCGGIGVDSDTVWNEMHSSSAVRMAVGCLVELAFKVAAGELKNGFAIIRPPGHHAEESTAMGFCFFNSVAITAKLLQQKLSVG-KVLIVDWDIHHGNGTQQAFYDDPSVLYISLHRYDNGNFFPGSGAPEEVGGGPGVGYNVNVAWTGGVDPPIGDVEYLTAFRTVVMPIAHEFSPDVVLVSAGFDAVEGHLSPLGGYSVTARCFGHLTRQLMTLAGGRVVLALEGGHDLTAICDASEACVSALLSVELQPLDEAVLQQKPSINAVATLEKVIEIQSKHWSCVQRFATGLGCSLREAQTGEKEEAETVSAMALLSMGAEQAQAAATQEHSPRPAEEPMEQEPAL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z2V6-1", "uniprot_id": "HDAC5_MOUSE", "id": "Q9Z2V6-1", "name": "Histone deacetylase 5", "aln": "-MNSPNE------------------SDGMSGREPSLGILPRTPLHSIPVAVEVKPVLPGAMPSSMGGGG---GGSPSPVELRG----ALAGPMDPALREQQLQQELLVLKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHLKQQQEMLAAK---------RQQELEQQRQREQQRQEELEKQRLEQQLLILRNKEKSKESAIASTEVKLRLQEFLLSKSKEPTPGGLNHSLPQHPKCWGAHHASLDQSSPPQSGPPGTPPSYKLP-LLGPYDSRDDFPLRKTASEPNLKVRSRLKQKVAERRS---SPLLRRKDGTVISTFKKRAVEITGTGPGVSSVCNSAPGSGPSSPNSSHSTIAENGFTGSVPN---IPTEMIP-QHRALPLDSSPNQFSLYTSPSLPNISLGLQATVTVTNSHLTASPKLSTQQEAERQALQSLRQGGTLTGKFMSTSSIPGCLLGVALE------------------------------GDTSPHGHASLLQHVCSWT-GRQQSTLIAVPLHGQSPLVTG-----------ERVATSMRTVGKLP-----------------------------------------------------RHRPLSRTQSSPLPQ----SPQALQQLVMQQQHQQFLEKQKQQQMQLGKILTKTGELSRQPTTHPEETEEELTEQQEALLGEG---------------------------------------------ALTIPREGSTESESTQEDLEEEEEEEE-EEEEDCIQVKDEDGESGPDEGPDLEESSAGYKKLFADAQQLQPLQVYQAPLSLAT-------------VPHQALGRTQSSPAAPGSMKSPTDQPTVVKHLFTTGVVYDTFMLKHQCMCGNTHVHPEHAGRIQSIWSRLQETGLLGKCERIRGRKATLDEIQTVHSEYHTLLYGTSPLNRQKLDSKKLLGPISQKMYAMLPCGGIGVDSDTVWNEMHSSSAVRMAVGCLVELAFKVAAGELKNGFAIIRPPGHHAEESTAMGFCFFNSVAITAKLLQQKLSVG-KVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGNFFPGSGAPEEVGGGPGVGYNVNVAWTGGVDPPIGDVEYLTAFRTVVMPIAQEFSPDVVLVSAGFDAVEGHLSPLGGYSVTARCFGHLTRQLMTLAGGRVVLALEGGHDLTAICDASEACVSALLSVELQPLDEAVLQQKPSVNAVATLEKVIEIQSKHWSCVQRFAAGLGCSLREAQTGEKEEAETVSAMALLSVGAEQAQAVATQEHSPRPAEEPMEQEPAL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UQL6-1", "uniprot_id": "HDAC5_HUMAN", "id": "Q9UQL6-1", "name": "Histone deacetylase 5", "aln": "-MNSPNE------------------SDGMSGREPSLEILPRTSLHSIPVTVEVKPVLPRAMPSSMGGGG---GGSPSPVELRG----ALVGSVDPTLREQQLQQELLALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHLKQQQEMLAAKQQQEMLAAKRQQELEQQRQREQQRQEELEKQRLEQQLLILRNKEKSKESAIASTEVKLRLQEFLLSKSKEPTPGGLNHSLPQHPKCWGAHHASLDQSSPPQSGPPGTPPSYKLP-LPGPYDSRDDFPLRKTASEPNLKVRSRLKQKVAERRS---SPLLRRKDGTVISTFKKRAVEITGAGPGASSVCNSAPGSGPSSPNSSHSTIAENGFTGSVPN---IPTEMLP-QHRALPLDSSPNQFSLYTSPSLPNISLGLQATVTVTNSHLTASPKLSTQQEAERQALQSLRQGGTLTGKFMSTSSIPGCLLGVALE------------------------------GDGSPHGHASLLQHVLLLEQARQQSTLIAVPLHGQSPLVTG-----------ERVATSMRTVGKLP-----------------------------------------------------RHRPLSRTQSSPLPQ----SPQALQQLVMQQQHQQFLEKQKQQQLQLGKILTKTGELPRQPTTHPEETEEELTEQQEVLLGEG---------------------------------------------ALTMPREGSTESESTQEDLEEEDEEDDGEEEEDCIQVKDEEGESGAEEGPDLEEPGAGYKKLFSDAQPLQPLQVYQAPLSLAT-------------VPHQALGRTQSSPAAPGGMKSPPDQP--VKHLFTTGVVYDTFMLKHQCMCGNTHVHPEHAGRIQSIWSRLQETGLLSKCERIRGRKATLDEIQTVHSEYHTLLYGTSPLNRQKLDSKKLLGPISQKMYAVLPCGGIGVDSDTVWNEMHSSSAVRMAVGCLLELAFKVAAGELKNGFAIIRPPGHHAEESTAMGFCFFNSVAITAKLLQQKLNVG-KVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGNFFPGSGAPEEVGGGPGVGYNVNVAWTGGVDPPIGDVEYLTAFRTVVMPIAHEFSPDVVLVSAGFDAVEGHLSPLGGYSVTARCFGHLTRQLMTLAGGRVVLALEGGHDLTAICDASEACVSALLSVELQPLDEAVLQQKPNINAVATLEKVIEIQSKHWSCVQKFAAGLGRSLREAQAGETEEAETVSAMALLSVGAEQAQAAAAREHSPRPAEEPMEQEPAL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FH14-1", "uniprot_id": "E7FH14_DANRE", "id": "E7FH14-1", "name": "Histone deacetylase", "aln": "MLLKPTVPGLCAMLQTIYETESCFSSDSTSSRERPVELLPQSRSTSMPSTVDVKTLLPSGMQSPVGGGGDQGGGSGGPVDLRTDPRLSALSAVDPSLREKQLQHELLLLKQQQELQKQLLFAEFQKQHEVLTRQHEVQLQEHLKQQQEILAAK---------RQQELEQKRKLEQQRHEEMEKQRLEQQLIMLRNKEKGKESAIASTEVKLKLQEFLLSK-KEPGPGGLNHSFPQ--KCWGAHHTSLEQSSPPQSNTPGTPPSYKLPPLLGSYEGKDDFPLRKTASEPNLKVRSRLKQKVAERRS---SPLLRRKDGTVISTFKKRAIEIS-----VSSMCSSAPGSGPSSPNSSNCAIAENGSSGSVPN---IHAEQLRSLHQSLTGDGAPSPLSLYTSPSLPNISLGLPA-----NAHITAPQKLSAQQEAERQTIQSLRQGGALTGKFISTSSLPTCLSTGAPHDP------------------------EPPAASNSHSSHSSLLQHVLLLEQARQQSALLAVPMYGQSPLVTG-----------ERVSNNMRTVNKLP-----------------------------------------------------RHRPLSRTQSAPLPQ----TPQALQHLVMQQQHQHFLEKQK--HYQLNKILSKGTDLPRQPPTHPEETEEELTETAEMQDERGE--------------------------------------------GPDHVREG-LQKDSSGETTPPSERIVPLKGESTESDLEEEDDEDEAVELRECDEDAP--YGQYLDQQHVQQLNVFQASLSITG-------------MPHRPLGRAQSSPVTS-SLKGTTLNEVPIKHLFTTGLVYDTFMLKHQCMCGNTNIHPEHAGRIQSVWSRLQETGLLGRCERIRGRKATLDEIQTVHSEYHTLLYGTSPLNRQKLDSKKLLGPISQKMYAVLPCGGIGVDSDTVWNEMHSSGAVRMAVGCVIELAFKVAAGELKNGFAVVRPPGHHAEESTAMGFCFFNSVAITAKLLQQKLGVG-KILIIDWDIHHGNGTQQAFYNDPNVLYISLHRYDDGNFFPGSGAPEEVGVGPGEGFNVNIAWTGGVEPPMGDVEYLTAFRTVVMPIANEFSPDVVLVSAGFDAVEGHQSPLGGYNVTAKCFGHLTKQLMKLAGGRVVLALEGGHDLTAICDASESCVEALLGDELNPLPLTVLQQKPCPKATASLERVIEIQSKHWTSLQRLAPTVGQSLLDAQRREKDEADTLTAMASLTVDNEQQ---TTSTETSRSAEEPMEEEPVL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9PHQ2-1", "uniprot_id": "M9PHQ2_DROME", "id": "M9PHQ2-1", "name": "histone deacetylase", "aln": "-------------------------MSSPDDRIPIHDLPSEAGSDERLLHITPATLTLDFKPHPAVDIDQQIMELKKSQELQKQ---RLINSFQEQSKQMELEHKLQLEHKYQKQPTNKRFSLELIVIIQFAVNSHGAFQELRNESMVTAAAAAVAQEQHRQQLHQQQQQHQQQQQQQQHQQQQQQQQARGRDGMKLKQNCSANASPEVKQILNCFILSR-KSQAAASNGTTTTSPYRNRGVVKSSSGESLPAGTVTSAHPYKIPQP-PPSLLKYESDFPLRKTASEPNLLK-IRLKQSVIERKARIGGPAGARRHERLLQAAQRRQQKNS-----VLTNCNSTPDSGPNSPPSAAALAVGVVGSRGSPTSAPIQEENEEGSQYQPGQRSSINDLPLFSSPSLPNISLGRPHLPNSAQAHAQVNAQVAAQAQAQAQAQAQAHAMFAALAAAQGGCGQPGYYNPLGMAFVGRQPAPLAMIPATGIAPQQPSPVVRSASATSTSSSQASLVGDVAPPQAHAASTILPSSSSYMQQLGSVAGSGVNLHAAAVAAAAAAAAAAGSLPPTNSHGHGHGSHAHPHPHAHGHGHGHGHGIYAGHQHNVPITDAQVAQVHLHKQGHRPLGRTQSAPLPLGHPMLTGAVQLNVVQTHYENSEAERQAYEHQVVNQKVRQTVLTRSGAAAAAAAAAGVSVVREAQLKEEDDDSAAEVMDLTDKKKPPKTVLTSTIATSTSQNLPEALAAAAAAAAYRAPHNASSNSASATKSGIKLRDQEYLQQQREQLLLLQQEEELAKSLMRPLSRTLSSPLVPLGPHGLSQIPDTGQQPAPIATSSSADHIPPVNLSLPHRQHRQLMSTLYASQLRNHQPSASGSPPHKVTTGLAYDPLMLKHSCICGDNAQHPEHSGRLQSVWARLNETDLVKRCDRLRARKATQEELQTVHTEAHAMLFGSNQCQLSRPKLENTLS----ASFVRLSCGGLGVDLDTTWNEHHTATAARMAAGCVIDLALKTAKGDLRNGFAVVRPPGHHAEANLAMGFCFFNSIAIAAKLLRQRMPEVRRILIVDWDVHHGNGTQQAFYQSPDILYLSIHRHDDGNFFPGTGGPTECGSGAGLGFNVNISWSGALNPPLGDAEYIAAFRTVVMPIARSFNPDIVLVSSGFDAATGHPAPLGGYHVSPACFGFMTRELLQLANGKVVLALEGGYDLAAICDSAQECVRALLGDPAAPIAKAELERPPCQNAINTLQKTIAIQQTHWPCVRMLEHTVGLSALETLKVEHDESETINAMAGLSMQSMHR------TLSRDDSEEPMDQDETK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 341, "similar_positions": 356, "identity": "25.93%" }, { "cls_id": "homologset.agr.MGI:1333785", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZNH9-1", "uniprot_id": "D3ZNH9_RAT", "id": "D3ZNH9-1", "name": "Olfactory receptor", "aln": "MGIWLNESSVDGFILLGIFSQSQTDFLLFSAVMLVFTVALCGNVLLILLIYTDPRLHTPMYFFLSQLSLMDLMLVCNIVPKMAVNFLSGRKSISFAGCGIQIGFFVSLVGSEGLLLGLMAYDRYVAISHPLHYPILMSQRVCLQIAGSSWAFGILDGIIQMVAAMSLPYCGSRYVDHFFCEVPALLKLACADTSLFDTLLFACCVFMLLLPFSIIVTSYARILGAVLRMHSAHSRKKALATCSSHLTAVSLFYGAAMFIYLRPRRYRAPSHDKVVSIFYTVLTPMLNPLIYSLRNREVMGALRKGLGRCKVGSQH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VGD6-1", "uniprot_id": "OR2V1_MOUSE", "id": "Q8VGD6-1", "name": "Olfactory receptor 2V1", "aln": "MGIWLNESSVDGFILLGIFSQSQTDLLLFSTVMLVFTVALCGNVLLILLIYTDPRLHTPMYFFLSQLSLMDLMLVCNIVPKMAVNFLSGRKSISFAGCGIQIGFFVSLVGSEGLLLGLMAYDRYVAISHPLHYPILMSQKVCLQIAGSSWAFGILDGIIQMVAAMSLPYCGSRYIDHFFCEVPALLKLACADTSLFDTLLFACCVFMLLLPFSIIVTSYARILGAVLRMHSAQSRKKALATCSSHLTAVSLFYGAAMFIYLRPRRYRAPSHDKVVSIFYTVLTPMLNPLIYSLRNREVMGALRKGLDRCRVGSQH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NHB1-1", "uniprot_id": "OR2V1_HUMAN", "id": "Q8NHB1-1", "name": "Olfactory receptor 2V1", "aln": "MGRWVNQSYTDGFFLLGIFSHSQTDLVLFSAVMVVFTVALCGNVLLIFLIYLDAGLHTPMYFFLSQLSLMDLMLVCNIVPKMAANFLSGRKSISFVGCGIQIGFFVSLVGSEGLLLGLMAYDRYVAVSHPLHYPILMNQRVCLQITGSSWAFGIIDGVIQMVAAMGLPYCGSRSVDHFFCEVQALLKLACADTSLFDTLLFACCVFMLLLPFSIIMASYACILGAVLRIRSAQAWKKALATCSSHLTAVTLFYGAAMFMYLRPRRYRAPSHDKVASIFYTVLTPMLNPLIYSLRNGEVMGALRKGLDRCRIGSQH", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** *:*:* .***:******:****::***:**:*************:*** *. ****************************.***********.******************************:**********.*:*****:********:**:*******.******* :******* ********************************::*** *******::**:: **************:********:***************.******************** **********.**::****", "identical_positions": 273, "similar_positions": 33, "identity": "86.67%" }, { "cls_id": "homologset.agr.MGI:1333786", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LQ08-1", "uniprot_id": "F1LQ08_RAT", "id": "F1LQ08-1", "name": "Carbonic anhydrase", "aln": "MRVLVSVVSLFFLG--IQALSE---WSYSGDDGLEESRWPEKYPSCG-GERQSPIDVKRREVHFSSSLLPLHMVNYEEEG-LELSMTNNGHTVQITLPNTMSMRDSD-----------GTVYRTKQMHFHWGGRDSEISGSEHTIDGMRHAIEIHLVHFN-EKYETYEKAVDQPDGLAVMAVLVKVEDYTENDYYSTFISELENVKYTGQTTTLRNVNIRNMLPG--DIRHYYTYQGSLTTPPCTENVKWFVFQDSATISKAQAERIENAVMDHHNQTIRNGYRRTQPLHNRVVEANFP-----------------------------------------YSPDEVSKNHFYMHEKISHGLKLKKIKKKRNHSH--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P18761-1", "uniprot_id": "CAH6_MOUSE", "id": "P18761-1", "name": "Carbonic anhydrase 6", "aln": "MRALVSVVSLFFLG--IQAHSD---WSYSGDDGVGESQWSEQYPSCG-GERQSPIDVKTEEVMFNPSLKPLSLVNYEKEN-LEFTMTNNGHTVSIDLPPSMYLETSD-----------GTEFISKAFHFHWGGRDWELSGSEHTIDGIRSIMEAHFVHFN-KEYGTYENAKDQKNGLAVLAVLFKIDEYAENTYYSDIISALKNIEKPGETTTLKDTTIRNLLPK--DVHHYYTYPGSLTTPPCTENVQWFVLRDKVTLSKAQVVTIENSVMDHNNNTIQNGYRSTQPNNHRVVEANFL-----------------------------------------NVQDMYSSYHLYLKNMQKEILQPKKQKKTKKNRHFWSRK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P23280-1", "uniprot_id": "CAH6_HUMAN", "id": "P23280-1", "name": "Carbonic anhydrase 6", "aln": "MRALVLLLSLFLLGGQAQHVSD---WTYS-EGALDEAHWPQHYPACG-GQRQSPINLQRTKVRYNPSLKGLNMTGYETQA-GEFPMVNNGHTVQISLPSTMRMTVAD-----------GTVYIAQQMHFHWGGASSEISGSEHTVDGIRHVIEIHIVHYN-SKYKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTTLTGLDVQDMLPR--NLQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLENSLLDHRNKTIHNDYRRTQPLNHRVVESNFP-----------------------------------------NQEYTLGSEFQFYLHKIEEILDYLRRALN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3ANQ1-1", "uniprot_id": "A0A8M3ANQ1_DANRE", "id": "A0A8M3ANQ1-1", "name": "Carbonic anhydrase", "aln": "MEQLTLVLLFVTSLNFASAGVDGDYWTYS--GELDQKHWAEKYHDCG-GQQQSPIDIQRRKVRYSPRMQQLELTGYEDIR-GSFLMKNNGHSVEIQLPSTMKITKGF-----------PHQYTAVQMHLHWGGWDLEASGSEHTMDGIRYMAELHVVHYNSEKYPSFEEAKNKPDGLAVLAFFFEDG-HFENTYYSDFISNLANIKYVGQSMSISNLNVLSMLSE--NLSHFYRYKGSLTTPPCFESVMWTVFDTPITLSHNQIRKLESTLMDHDNKTLWNDYRMAQPLNERVVESTFLPRLSKGGMCRQEEIEAKLKRIESLILSLDKKAVQASRPSSTGGKQPISPLVLYFPQKNVESFAVVNLTHPMELKSFTACMNVQIPPIRDLTVLSYSTSHDNELMISLGSEVGLWIGDEFVNLSFDLPSSDWTNYCLTWASHNGGAELWVNGVVGKERYIRTGYIIPAGGRLILGKDQDGFLGISVNDAFVGHMSDVNIWDYVLTEGEIVEQMSCDNGKVKGNVLSWGVTQLSLYGGVQLQGEQVCHRDNNNNRETEK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VB76-1", "uniprot_id": "Q9VB76_DROME", "id": "Q9VB76-1", "name": "Carbonic anhydrase", "aln": "MKLTAFLEASFLLICWSQAVSS-HVFGYS---EPNQRRWARHHGHCA-GKTQSPIAITTSRT-TAIHMPAVDMIGYHNLLPYPLKMINNGHTVSITIPKVNVTEVGEDFLPYIRGAKLPGEFEVEGLHFHWG--DKNNRGSEHVINDIRYTMEMHIVHRN-KKYATIGEALNHPDGAAVLGFFFNLD-EDEGAGLVTINRHLHLIADANQEATLNVTFSLSSLIAGVDVDKFYTYKGSLTTPPCSEAVTWILFPDPIPISPKQISRFR-QLSDTQDGALVDNFRTLQPVGNRRIFARTG---------------------------------------------HVRHTSIATLKHEGEYLKYDWFY---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VH26-1", "uniprot_id": "Q9VH26_DROME", "id": "Q9VH26-1", "name": "Carbonic anhydrase", "aln": "----MHLIALSLIVCCSVSFSWANEWGYPDLDNNQDEPFPKWGGLCDSGKKQSPINLH-VKGALKGEFDALKFENYDEHQ-KNLRMVNNGHSIQLSGFDHELTLSGG---------ALLQDFVVEQIHMHWW--------SEHTINDIRYPLEVHIVHRN-TIYPNMTMAANFKDGIVVIGVLYHVSNTPNEAIGSIIKSLGAVKSYDSMNKPVLVADSLAVDDLVPSVENYFTYAGSLTTPTCAEAVTWIVLTETFPVTLDQVNEFKEIEYDEG-KQLHNNYRELQSENNRAVVLVEQPE---------------------------------------QRSGSAGLTASVSLGLMTLILAGQKFLL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : *. : :.. * *: **** : . : : : .*. : * ****::.: . : :*:** ***.::.:* * *.** * * . * : :* .*:. : . : : . .: .: ::: * ******.* * * * :: :: * :. * : :.:* *. .* : : ", "identical_positions": 45, "similar_positions": 63, "identity": "8.09%" }, { "cls_id": "homologset.agr.MGI:1333787", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WVR3-1", "uniprot_id": "SHIP2_RAT", "id": "Q9WVR3-1", "name": "Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2", "aln": "MASVCGAPSPGGALGSQAPAWYHRDLSRAAAEELLARAGRDGSFLVRDSESVAGAFALCVLYQKHVHTYRILPDGEDFLAVQTSQGVPVRRFQTLGELIGLYAQPNQGLVCALLLPVEGEREPDPPDDRDASDVEDEKPPLPPRSGSTSISVPAGPSSPLPAPETPTTPAAESTPNGLSTVSHEYLKGSYGLDLEAVRGGASNLPHLTRTLVTSCRRLHSEVDKVLSGLEILSKVFDQQSSPMVTRLLQQQSLPQTGEQELESLVLKLSVLKDFLSGIQKKALKALQDMSSTAPPAPLQPSIRKAKTIPVQAFEVKLDVTLGDLTKIGKSQKFTLSVDVEGGRLVLLRRQRDSQEDWTTFTHDRIRQLIKSQRVQNKLGVVFEKEKDRTQRKDFIFVSARKREAFCQLLQLMKNKHSKQDEPDMISVFIGTWNMGSVPPPKNVTSWFTSKGLGKALDEVTVTIPHDIYVFGTQENSVGDREWLDLLRGGLKELTDLDYRPIAMQSLWNIKVAVLVKPEHENRISHVSTSSVKTGIANTLGNKGAVGVSFMFNGTSFGFVNCHLTSGNEKTTRRNQNYLDILRLLSLGDRQLSAFDISLRFTHLFWFGDLNYRLDMDIQEILNYISRREFEPLLRVDQLNLEREKHKVFLRFSEEEISFPPTYRYERGSRDTYAWHKQKPTGVRTNVPSWCDRILWKSYPETHIICNSYGCTDDIVTSDHSPVFGTFEVGVTSQFISKKGLSKTSDQAYIEFESIEAIVKTASRTKFFIEFYSTCLEEYKKSFENDAQSSDNINFLKVQWSSRQLPTLKPILADIEYLQDQHLLLTVKSMDGYESYGECVVALKSMIGSTAQQFLTFLSHRGEETGNIRGSMKVRVPTERLGTRERLYEWISIDKDDTG-AKSKAPSVLRGSQEHRSGSRKPTSTEASCPLSKLFEEPEKPPPTGRPPAPPRAVPREESLNPRLKSEGTPEQEGVAAPPPKNSFNNPAYYVLEGVPHQLLPLEPTSFARAPIPPTTKNKVAITVPAP----------------QLGRHRTPRVGEGSSSDEDSGG------TLPPPDFPPPPLPDSAIFLPPN---------------LDPLSMPVVRGRSVGEARGPPPPKAHPRPPLPPGTSPASTFL---EEVASADDRSCSVLQMAKTLSEVDYSP-GPGRSALLPNPLELQLPRG-PSDYGRPLSFPPPRIR-ESIQEDLAEEAPCP--QGGRASGLGEAGMGAWLRAIGLERYEEGLVHNGWDDLEFLSDITEEDLEEAGVQDPAHKRLLLDTLQLSK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6P549-1", "uniprot_id": "SHIP2_MOUSE", "id": "Q6P549-1", "name": "Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2", "aln": "MASVCGTPSPGGALGSPAPAWYHRDLSRAAAEELLARAGRDGSFLVRDSESVAGAFALCVLYQKHVHTYRILPDGEDFLAVQTSQGVPVRRFQTLGELIGLYAQPNQGLVCALLLPVEGEREPDPPDDRDASDVEDEKPPLPPRSGSTSISAPVGPSSPLPTPETPTTPAAESTPNGLSTVSHEYLKGSYGLDLEAVRGGASNLPHLTRTLVTSCRRLHSEVDKVLSGLEILSKVFDQQSSPMVTRLLQQQSLPQTGEQELESLVLKLSVLKDFLSGIQKKALKALQDMSSTAPPAPLQPSIRKAKTIPVQAFEVKLDVTLGDLTKIGKSQKFTLSVDVEGGRLVLLRRQRDSQEDWTTFTHDRIRQLIKSQRVQNKLGVVFEKEKDRTQRKDFIFVSARKREAFCQLLQLMKNRHSKQDEPDMISVFIGTWNMGSVPPPKNVTSWFTSKGLGKALDEVTVTIPHDIYVFGTQENSVGDREWLDLLRGGLKELTDLDYRPIAMQSLWNIKVAVLVKPEHENRISHVSTSSVKTGIANTLGNKGAVGVSFMFNGTSFGFVNCHLTSGNEKTTRRNQNYLDILRLLSLGDRQLSAFDISLRFTHLFWFGDLNYRLDMDIQEILNYISRREFEPLLRVDQLNLEREKHKVFLRFSEEEISFPPTYRYERGSRDTYAWHKQKPTGVRTNVPSWCDRILWKSYPETHIICNSYGCTDDIVTSDHSPVFGTFEVGVTSQFISKKGLSKTSDQAYIEFESIEAIVKTASRTKFFIEFYSTCLEEYKKSFENDAQSSDNINFLKVQWSSRQLPTLKPILADIEYLQDQHLLLTVKSMDGYESYGECVVALKSMIGSTAQQFLTFLSHRGEETGNIRGSMKVRVPTERLGTRERLYEWISIDKDDTG-AKSKVPSVSRGSQEHRSGSRKPASTETSCPLSKLFEEPEKPPPTGRPPAPPRAVPREEPLNPRLKSEGTSEQEGVAAPPPKNSFNNPAYYVLEGVPHQLLPLEPPSLARAPLPPATKNKVAITVPAP----------------QLGRHRTPRVGEGSSSDEDSGG------TLPPPDFPPPPLPDSAIFLPPN---------------LDPLSMPVVRGRSGGEARGPPPPKAHPRPPLPPGTSPASTFL---GEVASGDDRSCSVLQMAKTLSEVDYAP-GPGRSALLPNPLELQPPRG-PSDYGRPLSFPPPRIR-ESIQEDLAEEAPCP--QGGRASGLGEAGMGAWLRAIGLERYEEGLVHNGWDDLEFLSDITEEDLEEAGVQDPAHKRLLLDTLQLSK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15357-1", "uniprot_id": "SHIP2_HUMAN", "id": "O15357-1", "name": "Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2", "aln": "MASACGAPGPGGALGSQAPSWYHRDLSRAAAEELLARAGRDGSFLVRDSESVAGAFALCVLYQKHVHTYRILPDGEDFLAVQTSQGVPVRRFQTLGELIGLYAQPNQGLVCALLLPVEGEREPDPPDDRDASDGEDEKPPLPPRSGSTSISAPTGPSSPLPAPETPTAPAAESAPNGLSTVSHDYLKGSYGLDLEAVRGGASHLPHLTRTLATSCRRLHSEVDKVLSGLEILSKVFDQQSSPMVTRLLQQQNLPQTGEQELESLVLKLSVLKDFLSGIQKKALKALQDMSSTAPPAP-QPSTRKAKTIPVQAFEVKLDVTLGDLTKIGKSQKFTLSVDVEGGRLVLLRRQRDSQEDWTTFTHDRIRQLIKSQRVQNKLGVVFEKEKDRTQRKDFIFVSARKREAFCQLLQLMKNKHSKQDEPDMISVFIGTWNMGSVPPPKNVTSWFTSKGLGKTLDEVTVTIPHDIYVFGTQENSVGDREWLDLLRGGLKELTDLDYRPIAMQSLWNIKVAVLVKPEHENRISHVSTSSVKTGIANTLGNKGAVGVSFMFNGTSFGFVNCHLTSGNEKTARRNQNYLDILRLLSLGDRQLNAFDISLRFTHLFWFGDLNYRLDMDIQEILNYISRKEFEPLLRVDQLNLEREKHKVFLRFSEEEISFPPTYRYERGSRDTYAWHKQKPTGVRTNVPSWCDRILWKSYPETHIICNSYGCTDDIVTSDHSPVFGTFEVGVTSQFISKKGLSKTSDQAYIEFESIEAIVKTASRTKFFIEFYSTCLEEYKKSFENDAQSSDNINFLKVQWSSRQLPTLKPILADIEYLQDQHLLLTVKSMDGYESYGECVVALKSMIGSTAQQFLTFLSHRGEETGNIRGSMKVRVPTERLGTRERLYEWISIDKDEAG-AKSKAPSVSRGSQEPRSGSRKPAFTEASCPLSRLFEEPEKPPPTGRPPAPPRAAPREEPLTPRLKPEGAPEPEGVAAPPPKNSFNNPAYYVLEGVPHQLLPPEPPSPARAPVPSATKNKVAITVPAP----------------QLGHHRHPRVGEGSSSDEESGG------TLPPPDFPPPPLPDSAIFLPPS---------------LDPLPGPVVRGRGGAEARGPPPPKAHPRPPLPPGPSPASTFL---GEVASGDDRSCSVLQMAKTLSEVDYAPAGPARSALLPGPLELQPPRGLPSDYGRPLSFPPPRIR-ESIQEDLAEEAPCL--QGGRASGLGEAGMSAWLRAIGLERYEEGLVHNGWDDLEFLSDITEEDLEEAGVQDPAHKRLLLDTLQLSK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q2I6J1-1", "uniprot_id": "SHP2A_DANRE", "id": "Q2I6J1-1", "name": "Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2A", "aln": "MAAVGPASPP------PPPLWMHRDLSRAAAEELLARAGRDGSFLVRDSESVSGAYALCVLFQKHVHTYRILPDEENFLAVQTSQGVQPKRFKTLPELIQLYLQPSQGLVTTLLYPVERE---ETTEDRDYSDGEDEKPPLPPRTASTSSMT----GSALVSTDTP--PENVTAANGLSTISHEYLKGNYALDLEAVKQGANSLPHLNKTLLSSCKRLHGEVDKVLCGLEILSKVFDQQSASMVSRMIQQ-SMSQGGDQELEHLVTKLAILKDLLSSIEKKALKALQDMSSSTPAISPLLSIRN-KVIPVQTFEVKLDVYLADLTKIGKSQKYSLSVDVEGGKLVVMKKMKDAQEDWNTFTHDKIRQLIKSQRVQNKLGIVFEKEKDKSQRKDFIFASAKKREAFCQLLQLMKNKHSNQDEPDMISIFIGTWNMGSVPAPKPLGSWILSRGLGKTLDEMAVTIPHDIYVFGTQENSVCDKEWVETLRCSLKEYTDMEYKPIAVQTLWNIKIVVLVKAEHENRISHVGMSSVKTGIANTLGNKGAVGVSFMFNGTSFGFVNCHLTSGNEKIHRRNQNYLDILRQLSLGDKQLNSFDISLRFTHLFWFGDLNYRLDMDIQEILNYINRKEFDPLLKVDQLNLEREKNKIFLRFAEEEISYPPTYRYERGSRDTYVWQKQKATGMRTNVPSWCDRILWKSYPETHIVCNSYGCTDDIVTSDHSPVFGTFEVGVTSQFVSKKGLPKSSEQAYIEFENIEAIVKTASRTKFFIEFYSTCLEEFKKSYENDTQSSDNVNFLRVGWSSKQLTTLKPILSDIEYLQDQHLLLTVKSLDGYESYGECVLALKSMIGSTAQQFHTYLSHRGEETGNIRGSMRVRVPSERMGTRERLYEWISVDKDDMGGPKGRTLPPRTSHDYVKPTSSSSSRKHGSAELSRVSEEGEKSS-TSR-----HTHTKEE----NTHNRGKQDPFESDATTCKNSFNNPAYYILEGVPNQSAALASDILPGSALPPLANKTTAPPAGSVGKSKPPSGSSAQGRWQTSGRSVRPISEEGSSEDDGNIGPHTGSLNRPPPDFPPPPLPKAALEMSENSFGKPRVFSDLADGKIPPPSKPLVSPGLTPPPGGAPGGGVAFCIESPPVLSPNSAPFRRGGGASALDDQSCSVLQMAKTLSEVEYPS-GRERGAS-------QGPTG-PQLRG--LSFPSHPIQEESIAEDLPEEGGLWGAESSSSSLSVDCSVGEWLQKLGLQHYEEGLLHNGWDDLEFLSDITEEDLEEAGVRDPAHKKILLASLKQQQK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:. :. * .* * ******************************:**:*****:************ *:********** :**:** *** ** **.**** :** *** * :..:*** ** **********:.*** . .*.* :.:** * ::.*****:**:****.*.******: **. ****.:** :**:***.******.*************:.**:*::** .:.* *:**** ** **::***:**.*:************::*. . * *: *.****:******* *.**********::********:**:::: :*:****.*****:***************:*******::*******.**:**************:**:********:***********.** : **: *:****:***::***************** *:**:: ** .*** **::*:***:*:*****:.****.*********. ***************************************** *********** *****:**.:*******************************.*:**:***:**********:*:****:*****:**************.*:***.**:*********************:******************************:*****.*:*:*******.************************:***:***:*****:***:* ***:**.******:****************:**********:************* *:***************:****:**:***********:***: * .*.:. . . : :. * ..: .. *. **:: ** **.. *.* :: .:** . : .* : *.. **********:*****:* . . . :.:*. :::..* .. : *: * ****.*: . * . ***********.:*: :. . : * . *:* . *.* . ** ** *: : .:: **:**************:*.. * *.* * * * *. * ****. *: *** ***.**. :.. :* :..:. **: :**::*****:***********************:*****::** :*: .: ", "identical_positions": 835, "similar_positions": 238, "identity": "64.03%" }, { "cls_id": "homologset.agr.MGI:1333790", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q2PRI1-1", "uniprot_id": "Q2PRI1_DANRE", "id": "Q2PRI1-1", "name": "", "aln": "-MDNLTFRHSVLLVEGLKVTHQSSQPVFIVLFLSYIFAMISNITLIFLISTEKNLHDPMHFLFCNLPVNDIIGTTVILPRLMQDVLKEASERYISYTECVVQAYFVHVFTAACHYVLMIMAFDRYVAICNPLRYTAIMTNKMVIKLSASAWGLAIIVVTVMIGLTLRLSHCR-STIENPFCDNASLFKLSCENVSINNAFGVVYSVIVACLSAISIFITYVKIATVCLASKNKALNSKAMKTCSTHLAVYLIMFVSGAIFIFLHRF--PEYAE-SRKLGSIMFHIVPPGLNPLVYGLQTKEIRQRFVKLCRRKTSTSLM----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q2PRH9-1", "uniprot_id": "Q2PRH9_DANRE", "id": "Q2PRH9-1", "name": "", "aln": "-MDNLTFTNSILLVEGLKVTPQSSQPVFIMFLLAYIFAMVSNIGLIFLISTEKNLHDPMHFLFCNLPLNDIMGTTVIMPRLLQDILTEASERYISYAECAIQAYFVHVFTAACHYVLMIMAFDRYVAICNPLRYTAIMTNKMVIGLSALAWGLAIIFVTIMVGLSLRLSRCR-YKIENPFCDNASLFKLSCENVSVNNVFGLVYTVIVLSLSALSIFVTYVKIATVCVTSKNKALNSKAIKTCSTHLAVYLIMFVTGAVFIFLHRF--PEYSD-NRKLASIMFHIVPPGLNPLVYGLQTKEIRQKVVKLWCRKKSMIT-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q2PRH7-1", "uniprot_id": "Q2PRH7_DANRE", "id": "Q2PRH7-1", "name": "", "aln": "-MDNLTFTNDFLLVEGLKVTYPSSYPIFILLFLFYIFAMGCNIGLIILIATEKKLHHPMHFLFCNLPVNDIIGTTVILPRLICDIFKQTSERSMTYVECVVQAYFVHIFTTASHTALVTMAYDRQVAICNPLLYTAVMTDKMVVKLSATAWTLPIIVVAVMIGLTVRLSRCR-SKIENPFCDNASLYKLSCENVAINNIFGIVYSVAALIISVALMVIAYARIVTACIISKSKALNSKAIKTCSSHIAVYLIMFVSCAIMIFFHRF--PEYSE-NRKLASIMFHIVPPGLNPIVYGLQTKEIRQIIVKRWWKNAVDKL-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q32PT6-1", "uniprot_id": "Q32PT6_DANRE", "id": "Q32PT6-1", "name": "", "aln": "-MDNRTFRYSTLLVEGLQITQQSSQLTFIFLLTVYVFSMVSNIGILIQILAEKSLHQPMYILFCHLPMSDIIGATVLIPRLLKDLLTDPSERYITYIECVLQAFFTHLYGTTSHTILMIMAFDRYVAICNPLRYPTIMNNKMIVKLSAGAWGAAIVLVGILIGLSVRLSHCR-SVIENHVCDNPSLFKLSCENTFINNVYGLTFTVVLLTSSLGWVVLTYLRIAMVCIKSKHKATNSKAIKTCTTHLTVYIITIIFGFVPIFLHRF--SEYTE-SRKFGNVMFHVVPPGLNPIIYGLQAKEIKDKMLKLCVK-KVNPS-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q90426-1", "uniprot_id": "Q90426_DANRE", "id": "Q90426-1", "name": "", "aln": "-MDNQTFRSSTLLMEGLQVANQYRQLAFIFVLIAYIFIMIFNIGLLIQISSEKSLHQPMYILLCNLPLNDVFGTTLLLPRLLRNILLEPSERYITYVECVIQAFFGHLYGTTCHTILMIMAFDRYVAICNPLRYPAVMTSNMVVHLSAAAWGVAVVLVGILIGLTVRLSFCR-SVIENPFCDNASLFKLSCESTAINNIYGLSFTVVLLTSSLGSIALTYLRIAIVCFKSKNKATNSKAIKTCSTHLAVYLIMMVSGLTTITLHRF--PELSD-SRKLSSIIKHIVPPCLNPIIYGLQVKEIRQRLFKLISKSKVNFM-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q2PRD7-1", "uniprot_id": "Q2PRD7_DANRE", "id": "Q2PRD7-1", "name": "Olfactory receptor", "aln": "MYPNGSVFPLVLTLQSLELPQMSIYPAFIFGLTTYLFILFCNLTIVITICLNRSLHKPMYILLLNMPINDTMAATNFFSQLLYSIWSQDTS--ISYPACLLQGFIVHLYGGASYVILTAMAYDRYIAICCPLRYGAIMNSNNLIKIITGMWVFNFTVITVLFSLLLPYKICR-THMTDLFCYNPSIMKLMCEDTTVNNIIGLISLVLYHCIALSVVAFTYIHILITCVTNKQSDAKMKALQTCGTHLVVFLFLEFNTLFPLVAHRS--ESVPAYLRRVFSITVFVFPPIINPLVYGFKTKEIRQKMLTCFKRKMTSL------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q2PRE9-1", "uniprot_id": "Q2PRE9_DANRE", "id": "Q2PRE9-1", "name": "Olfactory receptor", "aln": "-MDNSTYFTTVILTGYIDIG-DIKYLCFVVLILLFAAIIVANLFIIGIICKEKSLHEPMYVFLCSLCANQLCGSFALFPFVLGNMLRSKTP-EVPLTVCHAQIFALYTYGQVEFCNLAMMSYDRYVAICHPLEYHRIMSPARTMTLIALGWSLQIIIFSLSFSVNVQLKLCG-NVLDKVWCDQYMLVKLACSDTTPNNIAGMTGIAVTIGAPLLLILFSYAKILRVCLKFKGQTAQ-KSLYTCILHLISLLNFAVGCSFELIQSRFGKLPMPAVVRVILSLYFLVCPPLFNPIMYGVRLANIKKALKKMICM-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0ACD6B7K1-1", "uniprot_id": "A0ACD6B7K1_DANRE", "id": "A0ACD6B7K1-1", "name": "Olfactory receptor", "aln": "-MENGANFTFIRLTGYLNLDFKMKYFLFAVLTVLYLTIICANSFLIGVICLAKILHKPMYMFLCSLFVNELYGSTALFPSLQVNLLLNDN--TISLVYCYLQIFCLCTYAMIDFCTLAVMSFDRYVSICYPLQYNKIMTPFRVGLLIALVWTYCFIQFFIFLSFKFKLQLCG-NVMEKVWCDNYLLVNLACSKSSLHNAYGIYLAVVTAVIPLTLIFYSYTRIIKICLSFSKEAKK-KALSTCTPHIISLLNFTLGCFFETLQSRFDEIRTPALIRVIVSLYLLMCQPLLNPILYAIRLKNIRLVCKNLVLSKIGIA------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q2PRA7-1", "uniprot_id": "Q2PRA7_DANRE", "id": "Q2PRA7-1", "name": "", "aln": "-MDNNSSFSMFSLT-ALNGSRSSRITIFSFALPGYFLTIFVNTLLILIIVLEKVLHQPMYIFLCNLCINGLYGATGFYPPLLYYLLSESN--VISLKECAIQSFAIFTYAIGEFTNLSVMAFDRYLAICRPLYYHNIMTTVTVWRLLTFIWMFPCCTAILLILMTLRFPICI-KKISKLYCETWVLERLVCGVDTAQFVFNG-ILTCAVNALVWFVFLSYINILVACK-HSVQNHK-KFISTCLPHLIAFLNYVFWSLFSTLYELFGISSLSQEFKNFLSVTFMIIPPLINPVIYGIVLTPIRTKAKHVFQSFRPKHID----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q2PRG1-1", "uniprot_id": "Q2PRG1_DANRE", "id": "Q2PRG1-1", "name": "", "aln": "-MEN---YTSFNFMLFENLG-YIRYSLFVLGFVLYFAIIFFNVLIMLAVFLERTLHQPMYILISCLSMNSLFGTAGFFPRVLSDLLSETH--SISREACFSQSFVIFTYVANEFSILMLMAFDRFAAICKPLRYHSIVRPRFLACLIVINLNCIMILLCVAALLTTKLRMCG-NKLFKVYCHSYEVLKLSCDNILINNAFGLLLVIITTIIPLGLILLSYVKILIICQRSSAQFKG-KAYQTCIPHIVILLNFTIAVTCDTTLSRVVNLQIPVGLSVFLSLEFLIIPPVLNPLIYAFNLPDIRKKMISLIKPLK---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M0R772-1", "uniprot_id": "M0R772_RAT", "id": "M0R772-1", "name": "Olfactory receptor", "aln": "MELYNLTGTLEFLLLGLSEDPEMQPILFVLFLLIYLFTVLGNVLIILAIGSDSHLHSPMYFFLYYLSLSDMGFSSTTIPKMLINLQTYKKS--ITYVACLSQVSFFFLFGCMDSLLLTVMAYDRWVAICHPLHYQVFLNPRLCRCLVIVSFFFSLMDSQVHYLMVSQLKFCTNLEIPHFFCDVTELLKLACTDTTISKIVIFLASIIIGFLPASGILYSYYKIISSIVRVTSSSGKYKAFSTCGSHLSVVCLFYGTGIGVYLSSSISSSSKQS---VIASVMYTTIVPMMNPFIYSLRNKDIKRALQKIFTQITHLTVKSINV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3Z9G7-1", "uniprot_id": "D3Z9G7_RAT", "id": "D3Z9G7-1", "name": "Olfactory receptor", "aln": "MEPYNTTGNLEFILLGLSEDPELQPILFVLFVLIYLFTVLGNVLIILAISSDSHLHSPMYFFLYNLSLSDMGFSSTTIPKMLMNMHTNNKS--ITYAACLTQVSFFFLFACMDSLLLTVMAYDRWVAICHPLHYQVILNPRLCKCLVIVSFCISLMDSQVHCLMVSQLKFCTNMNIPHFFCDVPELLKLACSDTSINNIVRFLFTIIFGFLPVSGIIYSYYKIISSIIRVPSLFGKNKAFSTCGSHLSVVCLFYGTGIGVYLSSTVSNFSRDS---VVASVMYSMLVPMMNPFIYSLRNRDMKKAVQSVFRQIA---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TRF6-1", "uniprot_id": "Q7TRF6_MOUSE", "id": "Q7TRF6-1", "name": "Olfactory receptor", "aln": "MEPYNLTGTLEFILLGLSEDPELQLILFALFLLIYLLTMLGNVLIILAISCDSHLHSPMYFFLYNLSLSDMGFSSTTIPKMLINLHAHKRS--TTYAECLTQVSFFILFGCMDSFLLAVMAYDRWVAICHPLHYQVILNPCRCRYLVVMSFCISLIDSQVHCFMVSQLTFCTNIEIPHFFCDVPELVKLACSNTTINDIAMFLSSIIVGFLPASGIFYSYYKITSSIFRVPSLLGKYKAFSTCGSHLSVVCLFYGTGIGVYLSSTVSGSSRES---MVASVMYTMVVPMMNPFIYSLRNRDIKKALWKIVCKIT---------", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * . : : * :: : ** **:.:: : . : . : : . * * : * *::** :** ** * .: : : . * : . * : .* * : :* .* * ** *: . .: * :**.:*.. :: ", "identical_positions": 31, "similar_positions": 45, "identity": "9.6%" }, { "cls_id": "homologset.agr.MGI:1333791", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AYE8-1", "uniprot_id": "ARTN_RAT", "id": "Q6AYE8-1", "name": "Artemin", "aln": "MELGLGEPTALSHCLRPRWQPALWPTLAALALLSSVTEASLDPMSRSPASRDVPSPVLAPPTDYLPGGHTAHLCSERALRPPPQSPQPAPPPPGPALQSPPAALRGARAARAGTRSSRARATDARGCRLRSQLVPVSALGLGHSSDELIRFRFCSGSCRRARSPHDLSLASLLDAGALRSPPGSRPISQPCCRPTRYEAVSFMDVNSTWRTVDHLSATACGCLG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z0L2-1", "uniprot_id": "ARTN_MOUSE", "id": "Q9Z0L2-1", "name": "Artemin", "aln": "MELGLAEPTALSHCLRPRWQSAWWPTLAVLALLSCVTEASLDPMSRSPAARDGPSPVLAPPTDHLPGGHTAHLCSERTLRPPPQSPQPAPPPPGPALQSPPAALRGARAARAGTRSSRARTTDARGCRLRSQLVPVSALGLGHSSDELIRFRFCSGSCRRARSQHDLSLASLLGAGALRSPPGSRPISQPCCRPTRYEAVSFMDVNSTWRTVDHLSATACGCLG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5T4W7-1", "uniprot_id": "ARTN_HUMAN", "id": "Q5T4W7-1", "name": "Artemin", "aln": "MELGLGGLSTLSHCPWPRQQPALWPTLAALALLSSVAEASLGSAPRSPAPREGPPPVLASPAGHLPGGRTARWCSGRARRPPPQPSRPAPPPPAP----PSALPRGGRAARAGGPGSRARAAGARGCRLRSQLVPVRALGLGHRSDELVRFRFCSGSCRRARSPHDLSLASLLGAGALRPPPGSRPVSQPCCRPTRYEAVSFMDVNSTWRTVDRLSATACGCLG", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*****. ::**** ** *.* *****.*****.*:****.. .****.*: *.****.*:.:****:**: ** *: *****..:******.* *.* **.****** .****::.************* ****** ****:************** *********.*****.******:**************************:**********", "identical_positions": 167, "similar_positions": 35, "identity": "74.55%" }, { "cls_id": "homologset.agr.MGI:1333792", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZUU3-1", "uniprot_id": "A0A8I5ZUU3_RAT", "id": "A0A8I5ZUU3-1", "name": "Sulfotransferase", "aln": "MARWPAPPPPPPPPPPLAAPPPVPGASTKGPPARKLLFMCTLSLSVTYLCYSLLGGSGSLQFPLALQEPPGSAAEPPPSLPPPSLPPPGVRPGASS-----PPPDNASRGPPPEPPERFTTPAADGWGLASGGG-ARDAWPRSPPAPGDAVTEQDALLG-RGAQELG-AAEELEGRRAANGSAERG-PASTPDYGEKKLPQALIIGVKKGGTRALLEAIRVHPDVRAVGVEPHFFDRNYEKGLEWYRNVMPKTLDGQITMEKTPSYFVTNEAPKRIHSMAKDIKLIVVVRNPVTRAISDYTQTLSKKPEIPTFEVLAFKNRTLGLIDASWSAIRIGIYALHLENWLQYFPLSQILFVSGERLIVDPAGEMAKVQDFLGLKRVVTEKHFYFNKTKGFPCLKKPEDSSAPRCLGKSKGRTHPRIDPDVIHRLRKFYKPFNMMFYQMTGQDFQWEQEEGDK------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3YVV6-1", "uniprot_id": "D3YVV6_MOUSE", "id": "D3YVV6-1", "name": "Sulfotransferase", "aln": "MARWPAPPPPPPPPPPLAAPPLLPGASTKGPPARKLLFMCTLSLSVTYLCYSLLGGSGSLQFPLALQEPPGSAAEPPPSLLSPSLPPPRVRPGASS-----PPPDNASRGPPPEPPERFTTPAADGWGLASGGG-ARDAWPRSPPAPGDAVTEQDALLG-RGAQEPG-AAEELEGRRAANGSAERG-PASTPDYGEKKLPQALIIGVKKGGTRALLEAIRVHPDVRAVGVEPHFFDRNYEKGLEWYRNVMPKTLDGQITMEKTPSYFVTNEAPKRIHSMAKDIKLIVVVRNPVTRAISDYTQTLSKKPEIPTFEVLAFKNRTLGLIDASWSAIRIGIYALHLENWLQYFPLSQILFVSGERLIVDPAGEMAKVQDFLGLKRVVTEKHFYFNKTKGFPCLKKPEDSSAPRCLGKSKGRTHPRIDPDVIHRLRKFYKPFNMMFYQMTGQDFQWEQEEGDK------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y661-1", "uniprot_id": "HS3S4_HUMAN", "id": "Q9Y661-1", "name": "Heparan sulfate glucosamine 3-O-sulfotransferase 4", "aln": "MARWPAPPPPPPPPPPLAAPPP-PGASAKGPPARKLLFMCTLSLSVTYLCYSLLGGSGSLQFPLALQESPGAAAEPPPSPPPPSLLPTPVRLGAPSQPPAPPPLDNASHGEPPEPPEQPAAPGTDGWGLPSGGGGAQDAWLRTPLAPSEMITAQSALPE-REAQESSTTDEDLAGRRAANGSSERGGAVSTPDYGEKKLPQALIIGVKKGGTRALLEAIRVHPDVRAVGVEPHFFDRNYEKGLEWYRNVMPKTLDGQITMEKTPSYFVTNEAPKRIHSMAKDIKLIVVVRNPVTRAISDYTQTLSKKPEIPTFEVLAFKNRTLGLIDASWSAIRIGIYALHLENWLQYFPLSQILFVSGERLIVDPAGEMAKVQDFLGLKRVVTEKHFYFNKTKGFPCLKKPEDSSAPRCLGKSKGRTHPRIDPDVIHRLRKFYKPFNLMFYQMTGQDFQWEQEEGDK------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QME4-1", "uniprot_id": "F1QME4_DANRE", "id": "F1QME4-1", "name": "Sulfotransferase", "aln": "MAFWSSTSVFTSKVP------------------RKILFMFTLSLSVTYLFYSLMSCYNSFQFQENYVYQGRLVTEET------TFVTLREKLYSSS-------SQGYLDEEFVERTATEQSLAISSVRNSAGIDERTPAWARAQAATTSSLSRAAAAAGEREHLEFSTTDSEL--RRVVN---------CTSDYGEKKLPQAIIIGVKKGGTRALLEALRVHPDVRAVGNEPHFFDRNYEKGLDWYRELMPSTLEGQITMEKTPSYFVTNSAPKRIHTMARDIKLIIVVRNPVTRAISDYTQTLSKRPEIPTFEVLAFKNRTLGLIDASWSALRIGIYALHLESWMQYFPLSQMHFVSGERLIVDPAGEMAKVQDFLGLKRIVTDKHFYFNKTKGFPCLKKPEDSSTPRCLGKSKGRTHPKIDPDVIRRLHKFYKPFNMMFYQMTGQNFQWELEEDGNSPGSRD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VWJ7-1", "uniprot_id": "Q9VWJ7_DROME", "id": "Q9VWJ7-1", "name": "", "aln": "MRDTAATSAQPAMIV-------------------MSIWCSSLSLSSRSLAIALVICVTLVYFSYSFN--------------ACLLASISRSLQQSN-------LRNLLALTSSPRNETNNAANSSSSNSSSSRNSSSTTGAPPAQTVTSSLDGAPKYQLLRQQGLRP----------------------------SRHLPDTLIIGVKKSGTRALLEFIRLHPDVRAAGSEVHFFDRHYQRGLRWYRHHMPYTIEGQITMEKTPSYFVTKEVPQRVYHMNPATKLLIVVRDPVTRAISDYTQAASKKADMKLFEQLAFVNGSYSVVDTNWGPVKIGVYARYLERWLLYFPLSQLLFISGERLIMDPAYEIGRVQDFLGLKRVVTEKHFYFNATKGFPCLFKSEARSTPHCLGKTKGRNHPHIDPGAIERLREFYRPFNNKFYQLTGINFAWP------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* .:.. .. :: :**** * :*: . * : . .. . : .. .:. . : . : . : * .::**:::******.******* :*:******.* * *****:*::** ***. ** *::**************:..*:*:: * **::***:***********: **:.:: ** *** * : .::*:.*..::**:** :** *: ******: *:******:*** *:.:*********:**:****** ******* *.* *:*:****:***.**:***..*.**::**:*** ***:** :* * ", "identical_positions": 169, "similar_positions": 94, "identity": "36.42%" }, { "cls_id": "homologset.agr.MGI:1333794", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P0C2C0-1", "uniprot_id": "RM22_RAT", "id": "P0C2C0-1", "name": "Large ribosomal subunit protein uL22m", "aln": "-------------MAAALLRELGALWVPN--------------------------------------------------------LRIWTTQMLR----------VLPQSCIHTSTSLDIS-----------RRWEKKNKIVYPPQLPG----------EPRRPAEIYHCRRQIKYSKDKMWYLAKLIRGMSIDQALAQLEFNDKKGAQIIKEVLLEAQDMAVRDHNVEFRSNLHIAESTSGR-GQCLKRIRYHGRGRFGIMEKVYCHYFVKLVEGPPPRP--EAPRTAVDHAKEYIQQLRSRTIIHTL------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BU88-1", "uniprot_id": "RM22_MOUSE", "id": "Q8BU88-1", "name": "Large ribosomal subunit protein uL22m", "aln": "-------------MAAALLRELGALRVPN--------------------------------------------------------LRIWATQTLR----------VLPPSCIHTSASLDIS-----------RKWEKKNKIVYPPQLPG----------EPRRPAEIYHCRRQIKYSKDKMWYLAKMIRGMSIDQALAQLEFNDKKGAQIIKEVLLEAQDMAVRDHNVEFRSNLHIAESTSGR-GQCLKRIRYHGRGRFGIMEKVYCHYFVKLVEGPPPPP--EVPKTAVDHAKDYIQQLRSRTIIHTL------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NWU5-1", "uniprot_id": "RM22_HUMAN", "id": "Q9NWU5-1", "name": "Large ribosomal subunit protein uL22m", "aln": "-------------MAAAVLGQLGALWIHN--------------------------------------------------------LRSRGKLALG----------VLPQSYIHTSASLDIS-----------RKWEKKNKIVYPPQLPG----------EPRRPAEIYHCRRQIKYSKDKMWYLAKLIRGMSIDQALAQLEFNDKKGAKIIKEVLLEAQDMAVRDHNVEFRSNLYIAESTSGR-GQCLKRIRYHGRGRFGIMEKVYCHYFVKLVEGPPPPP--EPPKTAVAHAKEYIQQLRSRTIVHTL------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VXB5-1", "uniprot_id": "RM22_DROME", "id": "Q9VXB5-1", "name": "Large ribosomal subunit protein uL22m", "aln": "--------------MHKVIRQMSQLRLQAPQGAA--------------------------------------------------LLRSADSSSISPAISPVSPP-ALQSKSLHTAASAGMLCAKWNKYNYGPRKWLEYNKTVHPPQETD----------EEPRNAYVCHMRSNIKYSPDKMWYIAAFVRGMSVDEALKQLNFVLKKGATDVKETILEAQQIAVERHNVEYKSNLWIAESFVGK-GRVFKGVRRHARGRFGKVEYKHCHYFVRLEEGEPPQHYYQEPQTPEQQYESWMEQMRSRKIINSL------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53881-1", "uniprot_id": "RM22_YEAST", "id": "P53881-1", "name": "Large ribosomal subunit protein uL22m", "aln": "MNFHTARISQVGVISRALLSSVSRRWIHVTPISLNNSGGSLFGSITENKPKEGKNRGDEDAGSFSNRLAIASDSSGEAPEVNRDSITIENDKLLQQHIISLQQPEQLASQSLLSPLKREIYEANCKIN----GGFYKKDTIVKLPNSSERYKLKLTKREIEVLEPSVYAQSYRIKSSMKKATLLLRLLGGLDVMKAISQCHFSNKKIAREVAELLQKGVKDGQKLG--LKPEDLYISQIWTGSDGFWRKRVEFKARTRIGIISHPYIHVRCILRTKSVTKRRLAYEAHLKEQKRAPWVQLGDKPIRGVTGGVYKW", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: .:. : : : * . : :. . : : : :. * *: . . : .** * .* : :: *:.: :*: * .* ** * : * : :. . . . .:* *:: * * * :. :.* *:* :. : * * . : . *: .: * ", "identical_positions": 27, "similar_positions": 58, "identity": "8.57%" }, { "cls_id": "homologset.agr.MGI:1333795", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZUX3-1", "uniprot_id": "A0A8I5ZUX3_RAT", "id": "A0A8I5ZUX3-1", "name": "Signal recognition particle subunit SRP72", "aln": "MASGGS-GGVSVPALWSEVNRYGQNSDFTRALKTVNKILQINKDD-VTALHCKVVCLIQNGSFKEALNVINTHTKVLANN--SLSFEKAYCEYRLNR-----------IENALKTIESANQQ--TDKLKELYGQVLYRLERYDECLAVYRDLVRNSQDDYDEERKTNLSA-VVAAQS-NWEKVVPVSMRVTHTHTHPTAMNEYSYLLSDRHVSLWQENLGLQEGTHELCYNAACALIGQGQLTQAMKILQKAEDLCRRSFSEDSDGTEEDPQAELAIIHGQMAYIMQLQGRIEEALQLYNQIIKLKPTDVALLAVIAN------NIITINKDQNVFDSKKKVKLTNAEGVEFKLSKRQLQAIEFNKALLAMYTNQAEQCRKIASSLQSQSPE-HLLPVLIQAAQLCREKQHTKAIELLQEFSDQHPENAAEIKLTMAQLKISQGNISKACLILR------SIEELKHKPGMVS-ALVTMYSHEEDIDSAIEVFTQAIQWYQSHQPKSPAHLSLIREAANFKLKYGRKKEAVSDLEQLWKQNSKDIHTLAQLISAYSLVDPEKAKALSKHLPSSDSMSLKVDVEALENSPGATYIRKKGGKVTGDNQPKEQGQGDLKKKK---KKKKGKLPKNYDPKVTPDPERWLPMRERSYYRGRKKGKKKDQIGKGTQGATAGASSELDASKTVSSPPTSPRPGSAATMASSTSNIVPPRHQKPAGAPATKKKQQQKKKKGGKSGW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F8VQC1-1", "uniprot_id": "F8VQC1_MOUSE", "id": "F8VQC1-1", "name": "Signal recognition particle subunit SRP72", "aln": "MASGGS-GGVSVPALWSEVNRYGQNSDFTRALKTVNKILQINKDD-VTALHCKVVCLIQNGSFKEALNVINTHTKVLANN--SLSFEKAYCEYRLNR-----------IENALKTIESATQQ--TDKLKELYGQVLYRLERYDECLAVYRDLVRNSQDDYDEERKTNLSA-VVAAQS-NWEKVVP-------------------------------ENLGLQEGTHELCYNAACALIGQGQLTQAMKILQKAEDLCRRSFSEDSDGAEEDPQAELAIIHGQMAYIMQLQGRTEEALQLYNQIIKLKPTDVALLAVIAN------NIITINKDQNVFDSKKKVKLTNAEGVEFKLSKRQLQAIEFNKALLAMYTNQAEQCRKIAASLQSQSPE-YLLPVLIQAAQLCREKQHTKAIELLQEFSDQHPENAAEIKLTMAQLKISQGNISKACLILR------SIEELRHKPGMVS-ALVTMYSHEEDIDSAIEVFTQAIQWYQSHQPKSPAHLSLIREAANFKLKYGRKKEAVSDLEQLWKQNSKDIHTLAQLISAYSLVDPEKAKALSKHLPSSDSMSLKVDVEALENSPGATYIRKKGGKVTGDNQPKEQGQGDLKKKK---KKKKGKLPKNYDPKVTPDPERWLPMRERSYYRGRKKGKKKDQIGKGTQGATAGASSELDASKAVSSPPTSPRPGSAATISSSASNIVPPRHQKPAGAPATKKKQQQKKKKGGKSGW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O76094-1", "uniprot_id": "SRP72_HUMAN", "id": "O76094-1", "name": "Signal recognition particle subunit SRP72", "aln": "MASGGS-GGVSVPALWSEVNRYGQNGDFTRALKTVNKILQINKDD-VTALHCKVVCLIQNGSFKEALNVINTHTKVLANN--SLSFEKAYCEYRLNR-----------IENALKTIESANQQ--TDKLKELYGQVLYRLERYDECLAVYRDLVRNSQDDYDEERKTNLSA-VVAAQS-NWEKVVP-------------------------------ENLGLQEGTHELCYNTACALIGQGQLNQAMKILQKAEDLCRRSLSEDTDGTEEDPQAELAIIHGQMAYILQLQGRTEEALQLYNQIIKLKPTDVGLLAVIAN------NIITINKDQNVFDSKKKVKLTNAEGVEFKLSKKQLQAIEFNKALLAMYTNQAEQCRKISASLQSQSPE-HLLPVLIQAAQLCREKQHTKAIELLQEFSDQHPENAAEIKLTMAQLKISQGNISKACLILR------SIEELKHKPGMVS-ALVTMYSHEEDIDSAIEVFTQAIQWYQNHQPKSPAHLSLIREAANFKLKYGRKKEAISDLQQLWKQNPKDIHTLAQLISAYSLVDPEKAKALSKHLPSSDSMSLKVDVEALENSAGATYIRKKGGKVTGDSQPKEQGQGDLKKKK---KKKKGKLPKNYDPKVTPDPERWLPMRERSYYRGRKKGKKKDQIGKGTQGATAGASSELDASKTVSSPPTSPRPGSAATVSASTSNIIPPRHQKPAGAPATKKKQQQKKKKGGKGGW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VDK7-1", "uniprot_id": "Q9VDK7_DROME", "id": "Q9VDK7-1", "name": "Signal recognition particle subunit SRP72", "aln": "MSKDANPKEALIKAAYADVNKFGNNQEFDKAVKAVNRILGVAPDD-PTALHCKVVCLVQLSKFEEAYKFIEKN----RLS--SLFFEKAYCEYQLNK-----------QQQALKTIDDAGLQPLPPNLKELRTQVLYRLERYDECLDSYRDIIKNTSDEYEEERRTNLSA-VAANLAVDQTKEVP----------------------------------EVPEDTYEQYFNSACIQANRQKYAEAERKLRTSEKLC----LEDECASEEEIIEEVDVIRVQLAYVLQLQGKTKEASSIYADCLRHKPKDAALVAVASN------NLVVVNKDQNVFDSKKKIRAALADACESRLTSRQKQVIALNNCLLALYTNAGDQVQQLSQKLAQTYPQVEFEALLIRCTQLAKDRKHKEAIEQLQKFAAAHKSHEFVSKFAIIQLQLLQGNRKDAIETLL------SLGEAKYKPGVVS-ALVSLYLGTDNKTAASALLKSAVDWYKKNEVSSGDLSDMWRQAAEFHLRGGASETAASSLEELLKLNPNDTKVLAQLVIAYAQFQPKRALELSRKLPKLETLTTASEIDALEAAN--WVMSAKAAKKTANTKVEPSPSTPLEKKKNRNRKRKGKLPKNYNAEVAPDPERWLPKYERTGFRKKRGGARGKDVIKGSQGMASGAADQYDMSSRVNLTKNSP--------------ATPVYQETAPGPRQQHRKGGHKKKKGGRF--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38688-1", "uniprot_id": "SRP72_YEAST", "id": "P38688-1", "name": "Signal recognition particle subunit SRP72", "aln": "-MAKDN-----LTNLLSQLNIQLSQDEHSQVEQTCVKLLDSGCENPADVFRRCLVAVIQQDKYQKALHYLKKFKHIDDKYGRKFALEKLYIFYKLNMPDEFNTLYTAIITDDLDTVLKKDIES-LRGILHVRAQYCYKNGLYQEAFKIYQHLASHNEKDQDSQIELSCNERVPLSVATELMNRSP-------------------------------LVTPMDESSYDLLFNESFIMASVGKYDKAIELLEK----------ALQGATNEGYQNDINTIKLQLSFVLQMVGKTAQSKEILKGLLQELKADSPFSLICQNNLNAFVDFSKYNTNFNLLLRELNVEKLNTFNLQT-FTHEQWSNIQRNVLFLRLFNNVKIHSQESLLSRTFDKYSKLVDNVTLESYKTQAKKLYHHTTKTILSGTDGSTIGILLLTIQLLIIEKEWENAIRIGELFLNESWKSSFEKFNDSQAIVCYILFELYKIKGRNNSKSVLLKKLGSVRVQLSGKIQENIPFWKHVGFELLSMGNAKESKALLREISNFSKGDADVLVDRVVSSDSLDIAQGIDLVRDIDIDKLIQLGVKPLES---------SAKRSKNTAVSKVQKRKVLELKKKRK--IKRLEKFLQGRDTSKLPDPERWLPLRDRSTYRPKKKQQGAKQTQGG--AMNKKSEQALDISKKG---------------------------------KPTVNKKPKNKKKGRK---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : :::* .: :. :. :: ::* :: .:: :*.::* ..:::* : ::. .: :** * *:** : *.*: . : : .: * *: *:*.: *:.: :...: :.: . . . * : : : * : *.::: :* : . : :* . *.. .::* :: *: *:::::*: *: :: .: :: * : : * :: *.: *:: : ::. : : :: .* . * * :* ::.* : :: . . . : :.. : .: : .: : : . : .: : :: * : *: : . . .:*. *. :* : ::.. . . . . : :... * * : : : *.:: : . * ..*.: : : .: :. * :.: . : . * .* *. .: : *:**: *: *: :. :.. ******** :*: :* :: .: * . : . * *. .* ::**** : ", "identical_positions": 75, "similar_positions": 222, "identity": "10.16%" }, { "cls_id": "homologset.agr.MGI:1333796", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K610-1", "uniprot_id": "A0A0G2K610_RAT", "id": "A0A0G2K610-1", "name": "", "aln": "----MNIHTKR-------------KIIKN-----------------------------------LTTLENRMLMFDGMPAVRVKTELLESEQGSPNVHNYPDMEAIPLLLNNVKGEPPEDSLPVDHFQTQTEPVDLSINKARTSPTAASSSPVSMTASASSPSSTSTSSSSSSRPASSPTVITSVSSASSSSTVLSPGPLVASASGMGGQQFLHIIHPVPPSSPMNLQSNKLSHVHRIPVVVQSVPVVYT-AVRSPGNVNNTIVVPLLEDGRSHGKAQMEPRGLSPRQSKSDSDDDDLPNVTLDSVNETGSTALSIARAVQEVHPSPVSRVRGNRMNNQKFACSISPFSIESTRRQRRSESPDSRKRRIHRCDFEGCNKVYTKSSHLKAHRRTHTGEKPYKCTWEGCTWKFARSDELTRHYRKHTGVKPFKCADCDRSFSRSDHLALHRRRHMLV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35738-1", "uniprot_id": "KLF12_MOUSE", "id": "O35738-1", "name": "Krueppel-like factor 12", "aln": "----MNIHMKR-------------KTIKN-----------------------------------LSALENRMLMLDGMPAVRVKTELVESEQGSPNVHNYPDMEAVPLLLNNVKGEPPEDSLPVDHFQTQTEPVDLSINKARTSPTAASSSPVSMTASASSPSSTSTSSSSSSRPASSPTVITSVSSASSSSTVLSPGPLVASASGVGGQQFLHIIHPVPPSSPMNLQSNKLSHVHRIPVVVQSVPVVYT-AVRSPGNVNNTIVVPLLEDGRSHGKAQMEPRGLSPRQSKSDSDDDDLPNVTLDSVNETGSTALSIARAVQEVHPSPVSRVRGNRMNNQKFACSISPFSIESTRRQRRSESPDSRKRRIHRCDFEGCNKVYTKSSHLKAHRRTHTGEKPYKCTWEGCTWKFARSDELTRHYRKHTGVKPFKCADCDRSFSRSDHLALHRRRHMLV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y4X4-1", "uniprot_id": "KLF12_HUMAN", "id": "Q9Y4X4-1", "name": "Krueppel-like factor 12", "aln": "----MNIHMKR-------------KTIKN-----------------------------------INTFENRMLMLDGMPAVRVKTELLESEQGSPNVHNYPDMEAVPLLLNNVKGEPPEDSLSVDHFQTQTEPVDLSINKARTSPTAVSSSPVSMTASASSPSSTSTSSSSSSRLASSPTVITSVSSASSSSTVLTPGPLVASASGVGGQQFLHIIHPVPPSSPMNLQSNKLSHVHRIPVVVQSVPVVYT-AVRSPGNVNNTIVVPLLEDGRGHGKAQMDPRGLSPRQSKSDSDDDDLPNVTLDSVNETGSTALSIARAVQEVHPSPVSRVRGNRMNNQKFPCSISPFSIESTRRQRRSESPDSRKRRIHRCDFEGCNKVYTKSSHLKAHRRTHTGEKPYKCTWEGCTWKFARSDELTRHYRKHTGVKPFKCADCDRSFSRSDHLALHRRRHMLV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58GCU3-1", "uniprot_id": "A0AC58GCU3_DANRE", "id": "A0AC58GCU3-1", "name": "", "aln": "MFPGRNPYMAHPPTGTPDSSSALYKTCQDPLCARLGWVCGQSRTASSRCHYCWGNCHSCQRLQLGDAINNRMLMLDGMPAVRVKAEPLESERGSPKVHGYPDMEAVPLLLSKVKAEPPEDLLSSDQFQTQTEPVDLSINKTRTSSPLSNNSPVT---SAFSPSSSSSSSS-------SPSVIASVSSGMPS--VLTSGSLVGSSHGVRGQQFLHIIHPVPPSSPSKLP----SQVHRIPVVVQSLPLMYTTSVRSPSTLSSTIMLPLLDEARCQDKAQTDPNGLSPRQIKSDSDDDDLPNVTLDSVNETGSTALSIARAVQD---------------------SMSPFSIESIRRPPPPESPDSKKRRIHRCDFAGCNKVYTKSSHLKAHRRTHTGEKPYKCTWDGCTWKFARSDELTRHYRKHTGVKPFKCGDCDRSFSRSDHLALHRRRHMLV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : : * :: :::*****:*********:* :***:***:**.******:****.:**.***** *. *:**************:***.. ..***: ** ****:*:*** **:**:****. .* **:.*.**.*: *: **************** :* *:**********:*::** :****..:..**::***::.* :.*** :*.****** ********************************: *:******* ** .*****:********* *****************************:***************************.**********************", "identical_positions": 275, "similar_positions": 63, "identity": "60.44%" }, { "cls_id": "homologset.agr.MGI:1333797", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5BK58-1", "uniprot_id": "Q5BK58_RAT", "id": "Q5BK58-1", "name": "", "aln": "-----MNFTEANYGMEDY---TGSD-YSMFPETEPCSLQEVRDFTKVFVPIAYSLICVFGLLGNIMVVITFAFYKKARSMTDVYLLNMAITDILFVLTLPFWAVTHATDTWIFGNTMCKLMKGTYAVNFNCGMLLLACISMDRYIAIVQATKSFRVRSRTLTHSKVICLTVWFVSIIISSPTFFFNKQYK----------------LQGRDVCEPQYKLVSEPITWKLLGMGLELLFGFFIPLLFMVFCYLFIIKTLVQAQNSKRHRAIRVVIAVVLVFLACQIPHNMVLLVTAANTGKMGRSCSAEKALAYARNVAEVLAFLHCCLNPVLYAFIGQKFRSYFMKIMKDVWCMRRKSKVPTFFCARVYSESYISRQTSETVEN---DNASSFTM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O54689-1", "uniprot_id": "CCR6_MOUSE", "id": "O54689-1", "name": "C-C chemokine receptor type 6", "aln": "-----MNSTESYFGTDDY---DNTEYYSIPPDHGPCSLEEVRNFTKVFVPIAYSLICVFGLLGNIMVVMTFAFYKKARSMTDVYLLNMAITDILFVLTLPFWAVTHATNTWVFSDALCKLMKGTYAVNFNCGMLLLACISMDRYIAIVQATKSFRVRSRTLTHSKVICVAVWFISIIISSPTFIFNKKYE----------------LQDRDVCEPRYRSVSEPITWKLLGMGLELFFGFFTPLLFMVFCYLFIIKTLVQAQNSKRHRAIRVVIAVVLVFLACQIPHNMVLLVTAVNTGKVGRSCSTEKVLAYTRNVAEVLAFLHCCLNPVLYAFIGQKFRNYFMKIMKDVWCMRRKNKMPGFLCARVYSESYISRQTSETVEN---DNASSFTM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P51684-1", "uniprot_id": "CCR6_HUMAN", "id": "P51684-1", "name": "C-C chemokine receptor type 6", "aln": "MSGESMNFSDVFDSSEDYFVSVNTSYYSVDSEMLLCSLQEVRQFSRLFVPIAYSLICVFGLLGNILVVITFAFYKKARSMTDVYLLNMAIADILFVLTLPFWAVSHATGAWVFSNATCKLLKGIYAINFNCGMLLLTCISMDRYIAIVQATKSFRLRSRTLPRSKIICLVVWGLSVIISSSTFVFNQKYN----------------TQGSDVCEPKYQTVSEPIRWKLLMLGLELLFGFFIPLMFMIFCYTFIVKTLVQAQNSKRHKAIRVIIAVVLVFLACQIPHNMVLLVTAANLGKMNRSCQSEKLIGYTKTVTEVLAFLHCCLNPVLYAFIGQKFRNYFLKILKDLWCVRRKYKSSGFSCAGRYSEN-ISRQTSETADN---DNASSFTM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A5PMT9-1", "uniprot_id": "A5PMT9_DANRE", "id": "A5PMT9-1", "name": "", "aln": "-------MINDSSENYNY-----GDYYEGA--VEPCSVESRQKLENFLRLFIHPIICVAGFIGNSLVIVTYALYKRTKSMTDVYLLNVAIADILFVVALPLIIYSEQH-SWAMGNMSCKLLRGIYSVNLYSGMLLLACISGDRYLAIVQARRSFRLRSSTLLYSHLVCAAVWLLALLLSLPTFIFYERYENGLTESTFLFNNNTIMEEIQYVCSFKFESNETARMMKTIVPSSQVAVGFFLPLLIMGFCYSSVIVTLLRAKNFQRHKAVRVVLTVVLVFVVCHMPYNLVLLYHTINLFEQ-QECSHEEAVALTMTITESLAYLHSCLNPLLYAFIGVNFRNHFRKILRDIWCLGKNYMSAR-RSSRVTTEMYLSTRRSMDYSN--NENGTSFTM", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "X1WFC0-1", "uniprot_id": "X1WFC0_DANRE", "id": "X1WFC0-1", "name": "", "aln": "-------MDNETNMDLEY-----SDDYA-----EPCPLMWYRDHEVTVQTYVYSLICALGLVGNVLVLLTYAFYKKAKSMTDVYLVNVALADLLFVVALPLIIHNERS-RWSMGTWACKLLRGAYSMNVYTSTLLLACISGDRYIAIVQARRSLRTRSQAKAYSRIICLAIWFLAFVLSLPTVIYHQ--------------------EKNQECITIFSEMETARLVKILIPSMQMVFGFLVPLMVMVFCYSWTMVTLLKAQNFQKHKAVRVVLAVFFVFVLCHLPYNVALLVYTSKLFVE-RSCGEEQVTLMTLSVSRTAAYLHCCLNPILYAFIGVKFRSHFCQILRDLRCLGKRYIYSG-RSSQQTSDLYVSATKTVAEQNGINDNPSSFTL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :* . * *.: :. . :.:**. *::** :*::*:*:**:::*******:*:*::*:***::**: .. * :. ***::* *::*. . ***:*** ***:***** :*:* ** : *:::* .:* ::.::* .*..: : : * : . . * : . :: .**: **:.* *** : **::*:* ::*:*:**:::*.:**: *::*:*:.** : : :.* *: : .::. *:**.****:****** :**.:* :*::*: *: :. . .: :: :* : .* :* :***:", "identical_positions": 111, "similar_positions": 125, "identity": "28.17%" }, { "cls_id": "homologset.agr.MGI:1333798", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WU06-1", "uniprot_id": "AVIL_RAT", "id": "Q9WU06-1", "name": "Advillin", "aln": "--------------------------------------------------------MSLSSAFRTVTNDPG-IITWRIEKMELVLVPLSAHGNFYEGDCYIILSTR---------------RVGSLLSQNIHFWIGKDSSQDEQSCAAIYTTQLDDYLGGSPVQHREVQYHESDTFRGYFKRGIIYKKGGVASGMKHVETNTYDVKRLLHVKGKRNIRATEVE-MSWDSFNQGDVFLLDLGMVIIQWNGPESNSGERLKAMLLAKDIRDRERGGRAEIGVIEGDKEAASPELMTVLQNTLGRRSIIKPAVP--DEVTDQQQKSTIMLYHVSDTTGQLSVTEVATRPLVQELLNHDDCYILDQSGTKIYVWKGKGATKVEKQAAMSKALDFIKMKGYPSSTNVETVNDGAESAMFKQLFQKWSVKDQTTG--LGKTFSIGKIAKIFQDKFDVTLLHTKPEVAAQERMVDDG--------NGKVEVWRIENLELVPVEYQWHGFFYGGDCYLVLYTYDVN---------GKPCYILYIWQGRHASQDELAASAYQAVEVDQQFGGAPVQVRVSMGKEPRHFMAIFKGKLVIYEG---GTSRKGNVEPDPPVRLFQIHGNDKSNTKAVEVSASASSLNSNDVFLLWTQAEH--YLWYGKGSSG-DERAMAKELAELLCDGDADTVAEGQEPPEFWD----------LLGGKAPYANDKRLQQE-------------------------------TLDIQVRLFECSNKTG-RFLVTEVTDFTQDDLSPGDVMLLDTWDQVFLWIGAEANATEKEGALSTAQEYLVTHPSGRDPDTP-ILIIKQGFEPPTFTGWFLAWDPHIWSEGKSYEQLKNELG-DATAIVRITTDMKNATLSLNSSESGPKYYPVEVLLKSQDQELPEDVDPTKKENYLSERDFVSVFGITRGQFVSLPGWKQLQLKKEAGLF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88398-1", "uniprot_id": "AVIL_MOUSE", "id": "O88398-1", "name": "Advillin", "aln": "--------------------------------------------------------MSLSSAFRAVSNDPR-IITWRIEKMELALVPLSAHGNFYEGDCYIVLSTR---------------RVGSLLSQNIHFWIGKDSSQDEQSCAAIYTTQLDDYLGGSPVQHREVQYHESDTFRGYFKQGIIYKKGGVASGMKHVETNTYDVKRLLHVKGKRNIQATEVE-MSWDSFNRGDVFLLDLGMVIIQWNGPESNSGERLKAMLLAKDIRDRERGGRAEIGVIEGDKEAASPGLMTVLQDTLGRRSMIKPAVS--DEIMDQQQKSSIMLYHVSDTAGQLSVTEVATRPLVQDLLNHDDCYILDQSGTKIYVWKGKGATKVEKQAAMSKALDFIKMKGYPSSTNVETVNDGAESAMFKQLFQKWSVKDQTTG--LGKIFSTGKIAKIFQDKFDVSLLHTKPEVAAQERMVDDG--------KGQVEVWRIENLELVPVEYQWHGFFYGGDCYLVLYTYDVN---------GKPHYILYIWQGRHASRDELAASAYRAVEVDQQFDGAPVQVRVSMGKEPRHFMAIFKGKLVIYEG---GTSRKGNEEPDPPVRLFQIHGNDKSNTKAVEVSASASSLNSNDVFLLRTQAEH--YLWYGKGSSG-DERAMAKELVDLLCDGNADTVAEGQEPPEFWD----------LLGGKTAYANDKRLQQE-------------------------------TLDVQVRLFECSNKTG-RFLVTEVTDFTQEDLSPGDVMLLDTWDQVFLWIGAEANATEKKGALSTAQEYLVTHPSGRDPDTP-ILIIKQGFEPPTFTGWFLAWDPHIWSEGKSYEQLKNELG-DATAIVRITADMKNATLYLNPSDGEPKYYPVEVLLKGQNQELPEDVDPAKKENYLSEQDFVSVFGITRGQFTALPGWKQLQLKKERGLF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75366-1", "uniprot_id": "AVIL_HUMAN", "id": "O75366-1", "name": "Advillin", "aln": "--------------------------------------------------------MPLTSAFRAVDNDPG-IIVWRIEKMELALVPVSAHGNFYEGDCYVILSTR---------------RVASLLSQDIHFWIGKDSSQDEQSCAAIYTTQLDDYLGGSPVQHREVQYHESDTFRGYFKQGIIYKQGGVASGMKHVETNTYDVKRLLHVKGKRNIRATEVE-MSWDSFNRGDVFLLDLGKVIIQWNGPESNSGERLKAMLLAKDIRDRERGGRAKIGVIEGDKEAASPELMKVLQDTLGRRSIIKPTVP--DEIIDQKQKSTIMLYHISDSAGQLAVTEVATRPLVQDLLNHDDCYILDQSGTKIYVWKGKGATKAEKQAAMSKALGFIKMKSYPSSTNVETVNDGAESAMFKQLFQKWSVKDQTMG--LGKTFSIGKIAKVFQDKFDVTLLHTKPEVAAQERMVDDG--------NGKVEVWRIENLELVPVEYQWYGFFYGGDCYLVLYTYEVN---------GKPHHILYIWQGRHASQDELAASAYQAVEVDRQFDGAAVQVRVRMGTEPRHFMAIFKGKLVIFEG---GTSRKGNAEPDPPVRLFQIHGNDKSNTKAVEVPAFASSLNSNDVFLLRTQAEH--YLWYGKGSSG-DERAMAKELASLLCDGSENTVAEGQEPAEFWD----------LLGGKTPYANDKRLQQE-------------------------------ILDVQSRLFECSNKTG-QFVVTEITDFTQDDLNPTDVMLLDTWDQVFLWIGAEANATEKESALATAQQYLHTHPSGRDPDTP-ILIIKQGFEPPIFTGWFLAWDPNIWSAGKTYEQLKEELG-DAAAIMRITADMKNATLSLNSNDSEPKYYPIAVLLKNQNQELPEDVNPAKKENYLSEQDFVSVFGITRGQFAALPGWKQLQMKKEKGLF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q07171-1", "uniprot_id": "GELS_DROME", "id": "Q07171-1", "name": "Gelsolin", "aln": "MDASGAATMAVLSSLLVFLALSSSLCSAGTLNARPAFPVQSGEIQPSGQNSKQAARRVMHPSFANAGRTPG-LEIWRIENFEPVIYPKTNYGKFYTGDSFIVLNTIEN-------------KKDKKLSWDVHFWLGLETSTDEAGAAAILTVQLDDLLNGGPVQHREVQDHESQLFLSYFKNGIRYEQGGVGTGFKHVETNAQGETRLFQVKGKRNVRVRQVN-LSVSSMNTGDCFILDAGSDIYVYVGSQAKRVEKLKAISAANQIRDQDHNGRARVQIVDDFSTDADKQHFFDVLGSGSADQVPDESTADEDSAFERTDAAAVSLYKVSDASGKLKVDIIGQKPLTQAMLDTRECFILD-TGSGIFVWVGKGATQKEKTDAMAKAQEFLRTKKYPAWTQIHRIVEGSESAPFKQYFDTWRDAGMSHSRLIRSALGIGSDELLNDDEIDSVVTQLKKSGGRAFGFMPDHGQNVIETITQYVAKPGSDEIVVSTVPFDEKLPLLGFASYVLTYNYEANN--------GDTGSLTYVWHGVKAS----AAARKRAFEEGLVGSKDGLLVQTNQGHEPRHFYKIFKGKLLTSFT---ALP--------VTAQLFRIRGTVESDVHASEVAADSSSLASSDAFVLHSGKSHKIYIWNGLGASAFEKQAAVDRFSDYWDDVELEQVEEGAEPDEFWE----------ELNGEGQYDR-SLGDDG-------------------------------APLLESRLFHCHLSSGGFLKVEEVAQYEQEDLDSDDIMLLDAGDEIYLWVGYGVSEEENGKLLDTAKLYFNLEPTARSFDTVSIIRVPQGKEPRVFKRMFPNWDDNYWQNQPSYEDMKQLVI-DANNEV-----------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q23989-1", "uniprot_id": "QUAI_DROME", "id": "Q23989-1", "name": "Villin-like protein quail", "aln": "-------------------------------------MELSLSPKETEIRPNTIPDLKVDATFRKVAKHAITFAIWKIDEDRLEAVQRSHYGTFYDSCAYIIYAASLSGHYANHETITREQKPNVSLERYIHYWLGKNVSEQNRSNVVHKIQELDSYLGNISSIYRETQNLESARFLSYFKKGYDVRSGALIS--------APQRPRLFQLYARKWLRSIEVATIDWSHFNSDYVMVLQTDNLTYVWIGRSSSGIERRSALDWVQKHCS----GSPITIVDDGYEQAMSQEHKELWNTMLPLKKRMVCQASQLVSEYADYNSNKFRIYKCNQRGRLHLDQLDVGMPAKDDLSDAHGVYLLDNYGQSIWLWVGGQAPQADALSAMGNGRAFVKKKKYPDNTLVVRVLEGHEPVEFKRLFANWLNVWQENT-------RGHKPVSTKFGKLDAHSLCERPKMAADTQLVDDG--------RGERVIYRVFGDQVQEVPISKTVVFTTNASFVVKYSVQCATVVPADLASVGIKTIIYQWNGSEASVESISRADKFAKASFDGLKEPGMFVQLYEFDEPPHFLQIFEGKLIIRRGQRTEMPYNGNSNALLDTFLLKVYGDASYNAKAVEETHLSS-ISSKDCYVIKTNHVW---VWCGQSSTG-DAREMAKAVGALMGENS--LVLEGKESKEFWQSVAMYFNQTLVINGNGNSCSSSTSSSSGAGSMCNGSSNGGNISPTLSNNCYLNTSVPSKPRPPVQLFLVWWQQS-SLRYEEILGFDQQDLSSDCTYILDTGSLTYVWLGSQAPNQER--YTAIAQSYVQNAPFGRRSATA-LAVVRQFQEPNVFKGFFESWQNDYGKNFHSYEKMRKDLGNKVTSNCCFASEGSALILNNRQKDFDGHKKYPLTVLIQEMDMLPPDINPLKREVHLTHDDFVSVFNMSFYEFDELPKWKKMELKKQFKLF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .:* . . . : *:*:: . : :*.** . .::: : : *. :*:*:* : * :: . .. :**. *.. . :**.* ** * .***.* ..*.: : : **::: .:: :: :* :. . :* . ::*: . : * .:. *: .*: .:. . * . : :. . . . .. . : . :*: .: * : : : ::** * *::* * *.: : **.:. *:: * ** * : : :* *.. **: * .* . .::* : . . :: * : * . : .::: *. : : * *:* .** : : * : *: ** ** **:***: . . *::: * . :.:* * . :* : *.* ::: : :* * .::. : : .. . : . * ** *. ***: :.*: . .. :** . . : *: : *:**.. :**: . ::*:* . *. *: *. * .* * : : * ** *. * *: . . :**.::: : .. ", "identical_positions": 117, "similar_positions": 211, "identity": "12.15%" }, { "cls_id": "homologset.agr.MGI:1333799", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q13426-1", "uniprot_id": "XRCC4_HUMAN", "id": "Q13426-1", "name": "DNA repair protein XRCC4", "aln": "MER----KISRIHLVSEPSITHFLQVSWEKTLESGFVITLTDGHSAWTGTVSESEISQEADDMAMEKGKYVGELRKALL---SGAGPAD--VYTFNFSKE-----SCYFFFEKNLKDVSFRLGSFNLEKVENPAEVIRELICYCLDTIAENQAKNEHLQKENERLLRDWNDVQGRFEKCVSAKEALETDLYKRFILVLNEKKTKIRSLHN--KLLNAAQEREKDIKQEGETAI------CSEMTADRDPVYDESTD--EESENQTDLSGLASAAVSKDDSIISSL-DVTDIAPSRKRRQRMQRNLGTEPKMAPQENQLQEKENSRPDSSLPETSKKEHISAENMSLETLRNSSPEDLFDEI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q924T3-1", "uniprot_id": "XRCC4_MOUSE", "id": "Q924T3-1", "name": "DNA repair protein XRCC4", "aln": "MER----KVSRIYLASEPNVPYFLQVSWERAIGSGFVITLTDGHSAWTATVSELEISQEADDMAMEKGKYIDELRKALV---PGSGAAG--TYKFLFSKE-----SQHFSLEKELKDVSFRLGSFNLDKVSNSAEVIRELICYCLDTITEKQAKNEHLQKENERLLRDWNDVQGRFEKCVSAKEALEADLYQRFILVLNEKKTKIRSLH---KLLNEVQQLEESTKPERENP-------CSDKTPEEHGLYDGSTD--EES----GAPVQAAETLHKDDSIFSSP-DVTDIAPSRKRRHRMQKNLGTEPKMAPQELPLQEKE--RLASSLPQTLKEESTSAENMSLETLRNSSPEDLFD--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A2R8RHK7-1", "uniprot_id": "A0A2R8RHK7_DANRE", "id": "A0A2R8RHK7-1", "name": "DNA repair protein XRCC4", "aln": "MSRCRSSSVRQISISSEPQRCFFLKLEWAEDLGSGFVIFLCDGESAWSGEVSEEDVSREAREMEMERDRYVCDLQLALTGAPSGSGASDEGEFTFQLTPERPGRPQLQLSYEKVQKDISFRLGVVDLQPVPEPTEVIRELITHGLEQSSRLQASNQHLLEENQKLRREQQHITEEMERYVKGKEALERDLYSRFVLVLNEKKAKLRALQQRVRELEEAEEERSPRKKKADSEDHEAVEAAADKSPDEESDYGGSTEDEQEAEPKRLDPKPPTEEMPECSPMDDSLNDITDVAPCRKRRHRHLQQLEAQAKRKTLEQQHRSREK-PVEETKAATSRTSSVPVK--PANTAANLDPDELFDDI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.* .: :* : ***. .**::.* . : ***** * **.***:. *** ::*:** :* **:.:*: :*: ** .*:*.:. :.* :: * . : ** **:***** .:*: * :.:******* : *: :. **.*:** :**::* *: :.: .:*: *..***** ***.**:*******:*:*:*: : *: .:: .. * : :. .:: :.:.. *. **: :*: . .: : : ..: .* *:**:**.****:* ::* ::.* . * :.:* .: . * : . ..: . :* * .*::*** ", "identical_positions": 115, "similar_positions": 124, "identity": "31.86%" }, { "cls_id": "homologset.agr.MGI:1333800", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z0M9-1", "uniprot_id": "I18BP_MOUSE", "id": "Q9Z0M9-1", "name": "Interleukin-18-binding protein", "aln": "MTMRHC-WTAGPSSWWVLLLYVH--VILARATSAPQTT--ATVLTGSSKDPCSSWSPAVP-TKQYPALDVIWPEKEVPLNGTLTLSCTACSRFPYFSILYWLGNGSFIEHLPGRLKEGHTSREHRNTSTWLHRALVLEELSPTLRSTNFSCLFVDPGQVAQYHIILAQLW----------------------------DGLKTAPSPSQETLSSHSPVSRSAGPGVA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F7F5P4-1", "uniprot_id": "F7F5P4_RAT", "id": "F7F5P4-1", "name": "Interleukin-18-binding protein", "aln": "MTMRHCGCAADPSPWWVLLLYVHV-VILARATSAPLTT--ATVLTRSSKDPCSSWSPAVP-TKQYPTLDVIWPEKEVPLNGTLTLSCTACSRFPNFSILYWLGNGSFIEHLPGRLREGHTSREQRNASTWLHRALVLEELSPSLLSTNFSCLFVDPGQVAQYHVILAQLWVRNLKEGIQGWEELHYLGKKGLAFPMQPDGLKTAPSPSQETLSSHSPGPRSAGPGAP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O95998-2", "uniprot_id": "I18BP_HUMAN", "id": "O95998-2", "name": "Interleukin-18-binding protein", "aln": "MTMRHN-WTPDLSPLWVLLLCAHVVTLLVRATPVSQTTTAATASVRSTKDPCPSQPPVFPAAKQCPALEVTWPEVEVPLNGTLSLSCVACSRFPNFSILYWLGNGSFIEHLPGRLWEGSTSRERGSTGTQLCKALVLEQLTPALHSTNFSCVLVDPEQVVQRHVVLAQLW----------------------------AGLRATLPPTQEALPSSHSSPQQQG----", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***** :.. *. ***** .* .:*.***... ** **. . *:****.* .*..* :** *:*:* *** ********:***.****** ******************** ** ****: .:.* * :*****:*:*:* ******::*** **.* *::***** **::: .*:**:*.* . .:. * ", "identical_positions": 115, "similar_positions": 47, "identity": "50.66%" }, { "cls_id": "homologset.agr.MGI:1333801", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P0C2C4-1", "uniprot_id": "RM10_RAT", "id": "P0C2C4-1", "name": "Large ribosomal subunit protein uL10m", "aln": "MPFSVEVEVFFLLVEDKLGWLPTLQPVRHGSKAVTRHRRVMHFQRQKLMAITEYIPPRPAVSPRCLPPPPKPPKE--ESGLIRLLRRDIAAVFRDNRMIAVCQNVALSAEDKLLLRHQLRKHKIFIKVFPSQVLKPFLEDSKYQN-LLPLFVGHNLLLVSEEP---KVKEMVRILKSVP-FLPLLGGCIDDTILSRQGFVEYAKLPSLDRLQGELVGGLTHLTAQ-TRYLLQHQPVQLTSLLDQYVRQQHEGDCATSTEGKPHPPDPAPDS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3TBW2-1", "uniprot_id": "RM10_MOUSE", "id": "Q3TBW2-1", "name": "Large ribosomal subunit protein uL10m", "aln": "MAAAVAG-ILRGGLPPRAAWLPTLQTVRHGSKAVTRHWRVMHFQRQKLMAITEYIPPKPAINPRCLPPPPKPPKE--ESGLVRLLRQDIVAVFRDNRMIAVCQNVALSAEDKLLLRHQLRKHKIFIKVFPSQVLKPFLENSKYRN-LLPLFVGHNLLLVSEEP---KVKEMVRVLKSVP-FLPLLGGCVDDTILSRQGLVDYAKLPSLDQLQGQLVGGLTHLMAQ-TRYLLQHQPVQLTSLLDQYVKEQNEGDCATSANEKLHPPDPAPDA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7Z7H8-1", "uniprot_id": "RM10_HUMAN", "id": "Q7Z7H8-1", "name": "Large ribosomal subunit protein uL10m", "aln": "MAAAVAG-MLRGGLLPQAGRLPTLQTVRYGSKAVTRHRRVMHFQRQKLMAVTEYIPPKPAIHPSCLPSPPSPPQE--EIGLIRLLRREIAAVFQDNRMIAVCQNVALSAEDKLLMRHQLRKHKILMKVFPNQVLKPFLEDSKYQN-LLPLFVGHNMLLVSEEP---KVKEMVRILRTVP-FLPLLGGCIDDTILSRQGFINYSKLPSLPLVQGELVGGLTCLTAQ-THSLLQHQPLQLTTLLDQYIREQREKDSVMSANGKPDP-DTVPDS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5BJB7-1", "uniprot_id": "RM10_DANRE", "id": "Q5BJB7-1", "name": "Large ribosomal subunit protein uL10m", "aln": "MAATLCC-----RLLPKAGWVPLTQSVRHGSKAVTRHKKPVHFQKQKLLAVTEYIPPTLSAPPAALAPRVKKTGE--ESSLAVMLRKDLENLFQEYKMIAVAQNNAISAEDMIHLKHRLKKHAINVKFFPNQVTRSFLNSSIYGN-MSPLIFGETVLLASKEP---KVKEMLQALRHNP-QIVLLGACIENTLFSYQGILSYSKLPSIAIIRGELVSGLTMMTSK-TVSMLHHHPAHLSALLQQYVKQQSSADTDKDASIQEAAA------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VPL3-1", "uniprot_id": "RM10_DROME", "id": "Q9VPL3-1", "name": "Large ribosomal subunit protein uL10m", "aln": "MATLIQR-----SLSLAKSSTPALQFLRFRGKINIQRPKAPHYERARVVAVTQPKYPELPKAKSCFKTRAERTQQQQENPYNEIIAREVRNWLDHSRLVAFFHLSSITADDIFRVRVQLHKQNLHLKSYGSKIIEQAVKNTRYEA-IVPLFHSNHCIVFSPDPE--KTAALLRIVRRVP-QMVLLGGIVEETMLSRNQLVAYAQMPGLHAVQAQLVQTLSQAPGH-LIQQLQAHQNSFVQVLDVHAKNQMNEETPKST-------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36521-1", "uniprot_id": "RM11_YEAST", "id": "P36521-1", "name": "Large ribosomal subunit protein uL10m", "aln": "----------MLQLRFMPGWVPRNGFFGLKETIGTVHKRFYALASE---QPSRKTVKPLDSRKTFLIDTYKHLME--NSSMIFFVHYNNLSKTEDH---HFRFKIKQTGGKLTKVRNNLFEVYLRNSHLPDPCGFVKRKEQNWKHPLLPLLKGPTATITYEDTNPQQVAKLLKVLQSAQDKLMVIGAKVENEVLNVEKINTFKTLPTKPEMQSQLVSVLQMLSGLGLVRTLENSSNALYLTLKSHNDNQKPKEDVESTTDAESKGSK----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . * . . : : :. : . : : :: : . . :. . :: .* : : . . :. : : **: . : :. :. ::: :: : ::*. ::: ::. : : : :* ::.:** * . *. : *. : :* : .: ", "identical_positions": 12, "similar_positions": 70, "identity": "4.43%" }, { "cls_id": "homologset.agr.MGI:1333802", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q80W66-1", "uniprot_id": "HS3S2_RAT", "id": "Q80W66-1", "name": "Heparan sulfate glucosamine 3-O-sulfotransferase 2", "aln": "----------MAYRVLGRAGPPQPRRARRLLFAFTLSLSCTYLCYSF-LCCCDGLGQSRLLGAPRCLRGPSASGQKLLAKSRPCDPPGPTPS--EPSAPSAPAAAAPAPRLSGSNHSGSPKPG----TKRLPQALIVGVKKGGTRAVLEFIRVHPDVRALGTEPHFFDRNYGRGLDWYRSLMPRTLETQITLEKTPSYFVTQEAPRRIFNMSRDTKLIVVVRNPVTRAISDYTQTLSKKPDIPTFEGLSFRNRSLGLVDVSWNAIRIGMYALHLESWLRYFPLAQIHFVSGERLITDPAGEMGRIQDFLGIKRFITDKHFYFNKTKGFPCLKKPESTLLPRCLGKSKGRTHVQIDPEVIDQLREFYRPYNIKFYETVGQDFRWE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q673U1-1", "uniprot_id": "HS3S2_MOUSE", "id": "Q673U1-1", "name": "Heparan sulfate glucosamine 3-O-sulfotransferase 2", "aln": "----------MAYRVLGRAGPPQPRRARRLLFAFTLSLSCTYLCYSF-LCCCDGLGQSRLLGAPRCLRGPSASGQKLLAKSRPCDPPGPTPS--EPSAPSAPAAAAPAPRLSGSNHSGSPKPG----TKRLPQALIVGVKKGGTRAVLEFIRVHPDVRALGTEPHFFDRNYGRGLDWYRSLMPRTLETQITLEKTPSYFVTQEAPRRIFNMSRDTKLIVVVRNPVTRAISDYTQTLSKKPDIPTFEGLSFRNRSLGLVDVSWNAIRIGMYALHLESWLRYFPLAQIHFVSGERLITDPAGEMGRIQDFLGIKRFITDKHFYFNKTKGFPCLKKPESTLLPRCLGKSKGRTHVQIDPEVIDQLREFYRPYNIKFYETVGQDFRWE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y278-1", "uniprot_id": "HS3S2_HUMAN", "id": "Q9Y278-1", "name": "Heparan sulfate glucosamine 3-O-sulfotransferase 2", "aln": "----------MAYRVLGRAGPPQPRRARRLLFAFTLSLSCTYLCYSF-LCCCDDLGRSRLLGAPRCLRGPSAGGQKLLQKSRPCDPSGPTPS--EPSAPSAPAAAVPAPRLSGSNHSGSPKLG----TKRLPQALIVGVKKGGTRAVLEFIRVHPDVRALGTEPHFFDRNYGRGLDWYRSLMPRTLESQITLEKTPSYFVTQEAPRRIFNMSRDTKLIVVVRNPVTRAISDYTQTLSKKPDIPTFEGLSFRNRTLGLVDVSWNAIRIGMYVLHLESWLQYFPLAQIHFVSGERLITDPAGEMGRVQDFLGIKRFITDKHFYFNKTKGFPCLKKTESSLLPRCLGKSKGRTHVQIDPEVIDQLREFYRPYNIKFYETVGQDFRWE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VWJ7-1", "uniprot_id": "Q9VWJ7_DROME", "id": "Q9VWJ7-1", "name": "", "aln": "MRDTAATSAQPAMIVMSIWCSSLSLSSRSLAIALVICVTLVYFSYSFNACLLASISRSLQQSNLRNLLALTSSPRNETNNAANSSSSNSSSSRNSSSTTGAPPAQTVTSSLDGAPKYQLLRQQGLRPSRHLPDTLIIGVKKSGTRALLEFIRLHPDVRAAGSEVHFFDRHYQRGLRWYRHHMPYTIEGQITMEKTPSYFVTKEVPQRVYHMNPATKLLIVVRDPVTRAISDYTQAASKKADMKLFEQLAFVNGSYSVVDTNWGPVKIGVYARYLERWLLYFPLSQLLFISGERLIMDPAYEIGRVQDFLGLKRVVTEKHFYFNATKGFPCLFKSEARSTPHCLGKTKGRNHPHIDPGAIERLREFYRPFNNKFYQLTGINFAWP", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * *:. .. . :* * :*:.:.:: .*:.*** * .:.:* . * * . ::. :: :: ......:.* ..*:..**.* . :. *.*: : : :::**::**:****.****:*****:****** *:* *****:* *** *** ** *:* ***:*********:*.*:*:::*. ***::***:***********: ***.*: ** *:* * : .:**..*..::**:*. :** ** ****:*: *:****** *** *:**:*****:**.:*:****** ******* *.*: *:****:***.* :*** .*::*******:* ***: .* :* * ", "identical_positions": 181, "similar_positions": 111, "identity": "47.14%" }, { "cls_id": "homologset.agr.MGI:1333803", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A9Z2-1", "uniprot_id": "D4A9Z2_RAT", "id": "D4A9Z2-1", "name": "DNA topoisomerase", "aln": "MKTVLMVAEKPSLAQSIAKILSRGNMSSHKGLNGACSVHKYTGTFAGQP-VHFKMTSVCGHVMTLDFLGKYNKWDKVDPAELFSQAPTEKKEANPKLNMVKFLQVEGRGCDYVVLWLDCDKEGENICFEVLDAVLPVLNNAHNGEKTVFRARFSSITDTDICNAMTRLTEPDHNEALSVDARQELDLRIGCAFTRFQTKYFQGKYGDLDSSLISFGPCQTPTLGFCVERHDKIQSFKPETYWVLQAKVHTDKEESLLLDWDRVRVFDREIAQMFLNMTKLEKEAWVEATSKKEKAKQRPLALNTVEMLRVASSALGMGPQHAMQVAERLYTQGYISYPRTETTHYPENFDLKGSLRQQANHPYWADSVKQLLAEGINRPRKGHDAGDHPPITPMKSATEAELGGDAWRLYEYITRHFIATVSHDCKYLQSTISFRIGPEHFTCMGKTVISPGFTEIMPWQSVPLEESLPTCQKGDTFTVGEVKMLEKQTSPPDYLTEAELITLMEKHGIGTDASIPVHINNICQRNYVTVENGRRLKPTNLGIVLVHGYHKIDAELVLPTIRSAVEKQLNLIAQGKANYHQVLGHTLDIFKRKFHYFVDSIAGMDELMEVSFSPLAATGKPLSRCGKCHRFMKYIQAKPSRLHCSHCDETYTLPQNGTIKLYKELRCPLDDFELVLWSSGSRGKSYPLCPYCYNHPPFRDMKKGMGCNECTHPTCQHSLSMLGIGQCVECENGVLVLDPTSGPKWKVACNTCSVVAHCFDNAHRVRVSADTCNTCEAALLDVDFNKAKSPLPGNETQHTGCIFCDTVFQELVELKHAASCHPMH-----RGGPGRRQGR-------GRARGRRPPGKPNP-------RRPKDKMSALAAYFV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z321-1", "uniprot_id": "TOP3B_MOUSE", "id": "Q9Z321-1", "name": "DNA topoisomerase 3-beta-1", "aln": "MKTVLMVAEKPSLAQSIAKILSRGNMSSHKGLNGACSVHKYTGTFAGQP-VHFKMTSVCGHVMTLDFLGKYNKWDKVDPAELFSQAPTEKKEANPKLNMVKFLQVEGRGCDYVVLWLDCDKEGENICFEVLDAVLPVMNNAHNGEKTVFRARFSSITDTDICNAMTRLSEPDHNEALSVDARQELDLRIGCAFTRFQTKYFQGKYGDLDSSLISFGPCQTPTLGFCVERHDKIQSFKPETYWVLQAKVHTDKEESLLLDWDRVRVFDWEIAQMFLNMTKLEKEAWVEATSRKEKAKQRPLALNTVEMLRVASSALGMGPQHAMQIAERLYTQGYISYPRTETTHYPENFDLKGSLRQQANHPYWADSVKQLLAEGINRPRKGHDAGDHPPITPMKSATEAELGGDAWRLYEYITRHFIATVSHDCKYLQSTISFRIGPEHFTCMGKTVISPGFTEIMPWQSVPLEESLPTCQKGDTFTVGEVKMLEKQTSPPDYLTEAELITLMEKHGIGTDASIPVHINNICQRNYVTVESGRRLKPTNLGIVLVHGYYKIDAELVLPTIRSAVEKQLNLIAQGKADYHQVLGHTLDIFKRKFHYFVDSIAGMDELMEVSFSPLAATGKPLSRCGKCHRFMKYIQAKPSRLHCSHCDETYTLPQNGTIKLYKELRCPLDDFELVLWSSGSRGKSYPLCPYCYNHPPFRDMKKGMGCNECTHPTCQHSLSMLGIGQCVECENGVLVLDPTSGPKWKVACNTCNVVAHCFENAHRVRVSADTCNTCEAALLDVDFNKAKSPLPGNETQHTGCIFCDPVFQELVELKHAASCHPMH-----RGGPGRRQGR-------GRGRGRRPPGKPNP-------RRPKDKMSALAAYFV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95985-1", "uniprot_id": "TOP3B_HUMAN", "id": "O95985-1", "name": "DNA topoisomerase 3-beta-1", "aln": "MKTVLMVAEKPSLAQSIAKILSRGSLSSHKGLNGACSVHEYTGTFAGQP-VRFKMTSVCGHVMTLDFLGKYNKWDKVDPAELFSQAPTEKKEANPKLNMVKFLQVEGRGCDYIVLWLDCDKEGENICFEVLDAVLPVMNKAHGGEKTVFRARFSSITDTDICNAMACLGEPDHNEALSVDARQELDLRIGCAFTRFQTKYFQGKYGDLDSSLISFGPCQTPTLGFCVERHDKIQSFKPETYWVLQAKVNTDKDRSLLLDWDRVRVFDREIAQMFLNMTKLEKEAQVEATSRKEKAKQRPLALNTVEMLRVASSSLGMGPQHAMQTAERLYTQGYISYPRTETTHYPENFDLKGSLRQQANHPYWADTVKRLLAEGINRPRKGHDAGDHPPITPMKSATEAELGGDAWRLYEYITRHFIATVSHDCKYLQSTISFRIGPELFTCSGKTVLSPGFTEVMPWQSVPLEESLPTCQRGDAFPVGEVKMLEKQTNPPDYLTEAELITLMEKHGIGTDASIPVHINNICQRNYVTVESGRRLKPTNLGIVLVHGYYKIDAELVLPTIRSAVEKQLNLIAQGKADYRQVLGHTLDVFKRKFHYFVDSIAGMDELMEVSFSPLAATGKPLSRCGKCHRFMKYIQAKPSRLHCSHCDETYTLPQNGTIKLYKELRCPLDDFELVLWSSGSRGKSYPLCPYCYNHPPFRDMKKGMGCNECTHPSCQHSLSMLGIGQCVECESGVLVLDPTSGPKWKVACNKCNVVAHCFENAHRVRVSADTCSVCEAALLDVDFNKAKSPLPGDETQHMGCVFCDPVFQELVELKHAASCHPMH-----RGGPGRRQGR-------GRGRARRPPGKPNP-------RRPKDKMSALAAYFV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B6B7-1", "uniprot_id": "A0ACD6B6B7_DANRE", "id": "A0ACD6B6B7-1", "name": "DNA topoisomerase", "aln": "MRTVLMVAEKPSLAQSIAKILSKGSCSTRKGLNGACSVHEYMGSFTGQN-VRFKMTSVCGHVMSLDFIGKYNNWDKVDPAELFSKAPTEKKEANPKLNMVKFLQVEAKGCDYVVLWLDCDKEGENICFEVLDAIQPVMNKPYGNERTVYRAKFSSITDTDICNAMNRLGEPNKNEALSVDARQELDLRIGCAFTRFQTKYFQGKYGNLDSSLISFGPCQTPTLGFCVERHDKIQSFKPEAYWVVQAKVFKGKDSPLTLDWDRVRVFDRDIGQMFVNMAKTAKEARVDSVTKKEKAKQRPLALNTVEMLRVASSALGMGPQHTMQIAERLYTQGYISYPRTETTHYPENFDLKGTLKQQANSTFWGETVKALLSEGINRPRKGADAGDHPPITPMRAASESELGSDGWRLYDYITRHFIATVSPDCKYLQTTISFSIATEGFTCSGKTLISAGYTEVMPWQGIAQEEALPVCERGDMFTVDEIKLLEKQTNPPDYLTEAELITLMEKHGIGTDASIPVHINNICQRNYVTVESGRKLKPTNLGIVLVHGYYKIDADLVLPTIRSAVEKQLTLIALGKANFQQVLQHTLDIFKRKFHYFVDSIAGMDELMEVSFSPIAATGKPLSRCGKCHRFMKYIQAKPSRLHCSHCDETYSLPQNGAIKLYKELKCPLDEFELVLWTSGSRGKSYPVCPYCFSNPPFRDMKKGMGCNECTHPSCQHSLNSLGIGQCVECETGVLVFDPTSGPKWRMACNKCNVVVHFFEQAHKVQVSQDSCDSCEASLVIVDFNKTRSPLPDGETQHTGCVFCDSAFQDLVELKHATMRHPMH-----RAG-GARRGR-------GKGRGRRPMGRGNP-------KKPKDKMAALAAYFV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O96651-1", "uniprot_id": "TOP3B_DROME", "id": "O96651-1", "name": "DNA topoisomerase 3-beta", "aln": "MKSVLMVAEKPSLAASLAGILSNGRCTAKRGTGNGCSTHEWTGNFRNEGSVHFRMTSVCGHVMSLDFNKKYNCWDKVDPIQLFG-CATEKKETNPKQNMRKFLAHEARGCDYLVLWLDCDKEGENICFEVMDAVKHVINNVYS-DQVTYRAHFSAITEKDIKKAMETLGHPNENEAKSVDARQELDLRIGCAFTRFQTKFFQDRYGDLDSSLISYGPCQTPTLGFCVKRHDDIQTFKPESFWHLQLLAGQPE---VTLEWARGRVFKKDIAIMLLNRVKEHKKATVESVASKEAYKSKPQALNTVELMRICSSGLGIGPFQAMQIAERLYTQGYISYPRTETNQYPTNFDLPAVLHVLKPSADFGEEARSILGD-IQTPRKGKDAGDHPPITPMKLGNRSDFDRDTWRVYEFICRHFMGTVSRDLKYRVTTAKLSVGMETFSCTASVLIDAGFTKVMTWSAFGKDEPQPPFVQGTQVAINDVRLIESQTGPPDYLTESELITLMEEHGIGTDASIPVHINNICQRNYVHIENGRKLMPTTLGIVLVHGYQKIDPELVLPTMRTEVERMLTLIAQGSANFQDVLRHAIKIFKLKFMYFVKNIDSMDALFEVSFSPLAESGKAHSRCGKCRRYMKYIQTKPARLHCSHCDETYALP-IGNVKVYREFKCPLDDFDLLAFSTGVKGRSYPFCPYCYNHPPFSDMPHLGGCNTCTNANCPHSLNTLGISSCVECPTGVLVLDCTLAPTWKLGCNRCDVIINCFKGATKITVEEAKCQECGAQQVNVVYKSDKSKFKDGSEEKSGCIFCSADFSHLVEKHRAVASRPVRSGGGFRGGKAGRGGGGMGGAAFGSGGAVTAGGGPNAGGGVRGSRVAKDKMGQLASYFV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*::*********** *:* ***.* ::::* ...**.*:: *.* .: *:*:*********:*** *** ****** :**. ..*****:*** ** *** *.:****:*****************:**: *:*: :. ::..:**:**:**:.** :** * .*:.*** **********************:**.:**:*******:************:***.**:****::* :* . : : *:* * ***. :*. *::* .* *:* *::.: ** *.:* ******::*:.**.**:** ::** *****************.:** **** . *: . :.: .: :*.: *: **** ***********: ...:::. * **:*::* ***:.*** * ** :* .: :. * *:* ...::..*:*::*.*... :*. * :* ..:.:::::*.**.*******:*******:********************** :*.**:* **.********* ***.:*****:*: **: *.*** *.*::::** *::.:** ** ***..* .** *:******:* :**. ******:*:*****:**:***********:** * :*:*:*::****:*:*: :::* :*:***.****:.:*** ** : *** **:..* ***. ***..**** .****:* * .*.*::.** *.*: : *. * :: *. .*. * * : * ::. :* : ... :: **:**.. *..*** ::*. :*:: *.* . * * * . . . * *. : .****. **:***", "identical_positions": 464, "similar_positions": 249, "identity": "52.61%" }, { "cls_id": "homologset.agr.MGI:1333804", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P61759-1", "uniprot_id": "PFD3_MOUSE", "id": "P61759-1", "name": "Prefoldin subunit 3", "aln": "MAAAKDGCG-LETAAGNGRRLHLGIPEAVFVEDVDSFMKQPGNETADTVLKKLDEQYQKYKFMELNLAQKKRRLKGQIPEIKQTLEILKYMQKK----KESTNSMETRFLLADNLYCKASVPPTD-----KVCLWLGANVMLEYDIDEAQALLEKNLSTATKNLDSLEEDLDFLRDQFTTTEVNMARVYNWDVKRRNKDDSTKNKA-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P61758-1", "uniprot_id": "PFD3_HUMAN", "id": "P61758-1", "name": "Prefoldin subunit 3", "aln": "MAAVKDSCGKGEMATGNGRRLHLGIPEAVFVEDVDSFMKQPGNETADTVLKKLDEQYQKYKFMELNLAQKKRRLKGQIPEIKQTLEILKYMQKK----KESTNSMETRFLLADNLYCKASVPPTD-----KVCLWLGANVMLEYDIDEAQALLEKNLSTATKNLDSLEEDLDFLRDQFTTTEVNMARVYNWDVKRRNKDDSTKNKA-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VGP6-1", "uniprot_id": "PFD3_DROME", "id": "Q9VGP6-1", "name": "Prefoldin subunit 3", "aln": "MTGIMDSVEMPKLPEN--QKTFAGIPEAVFLEEIDTFMSQPENENCEKVLQRLDEQHGKYRFMACNLEARRRKLKSQIPDLERSLEMVNVLRKE----DEER---ETQFLLSDQVFIKTLVPPTK-----TVYLWLGASVMLEYPLDEAEALLNQNITSAVGNLKSVEHDQDFLRDQITTTEVNMARVYNWGVKKRQAATKTTATTPS---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P48363-1", "uniprot_id": "PFD3_YEAST", "id": "P48363-1", "name": "Prefoldin subunit 3", "aln": "MDTLFNSTE----------KNARGIPQAPFIENVNEIIKDPSD--FELCFNKFQERLSKYKFMQESKLATIKQLKTRIPDLENTLKICQSLRNHSDEGDESDEPILLHYQLNDTLYTKAQVDIPEDRADLKVGLWLGADVMLEYPIDEAIELLKKKLADSEQSLTVSTEDVEFLRENITTMEVNCARLYNWDVQRRQDLKQAQEGTKNLKI", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :. : ***:* *:*::: ::.:* : : :::::*: **:** . ::** :**:::.:*:: : :::. .*. :: * * :: *: * .. .* *****.***** :*** **::::: : .* .* :***:::** *** **:***.*::*: .: : ", "identical_positions": 56, "similar_positions": 69, "identity": "26.54%" }, { "cls_id": "homologset.agr.MGI:1333805", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9R0U0-1", "uniprot_id": "SRS10_MOUSE", "id": "Q9R0U0-1", "name": "Serine/arginine-rich splicing factor 10", "aln": "MSRYLRPPNTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFEDVRDAEDALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYSSSRYDDYDRYRRSRSRSYERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDRFKHRNRSFSRSKSNSRSRSKSQPKKEMKAKSRSRSASHTKTRGTSKTDSKTHYKSGSRYEKESRKKEPPRSKSQSRSQSRSRSKSRSRSWTSPKSSGH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6A795-1", "uniprot_id": "A0A8I6A795_RAT", "id": "A0A8I6A795-1", "name": "Serine/arginine-rich splicing factor 10", "aln": "MSRYLRPPNTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFEDVRDAEDALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYSSSRYDDYDRYRRSRSRSYERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDRFKHRNRSFSRSKSNSRSRSKSQPKKEMKAKSRSRSASHTKTRGTSKTDSKTHYKSGSRYEKESRKKEPPRSKSQSRSQSRSRSKSRSRSWTSPKSSGH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75494-1", "uniprot_id": "SRS10_HUMAN", "id": "O75494-1", "name": "Serine/arginine-rich splicing factor 10", "aln": "MSRYLRPPNTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFEDVRDAEDALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYSSSRYDDYDRYRRSRSRSYERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDRFKHRNRSFSRSKSNSRSRSKSQPKKEMKAKSRSRSASHTKTRGTSKTDSKTHYKSGSRYEKESRKKEPPRSKSQSRSQSRSRSKSRSRSWTSPKSSGH", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**********************************************************************************************************************************************************************************************************************************************************************", "identical_positions": 262, "similar_positions": 0, "identity": "100.0%" }, { "cls_id": "homologset.agr.MGI:1333806", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q14061-1", "uniprot_id": "COX17_HUMAN", "id": "Q14061-1", "name": "Cytochrome c oxidase copper chaperone", "aln": "----------MPGLVDSNP---------------APPESQEKKPLKPCCACPETKKARDACIIEKGE--EHCGHLIEAHKECMRALGFKI----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P56394-1", "uniprot_id": "COX17_MOUSE", "id": "P56394-1", "name": "Cytochrome c oxidase copper chaperone", "aln": "----------MPGLAAASP---------------APPEAQEKKPLKPCCACPETKKARDACIIEKGE--EHCGHLIEAHKECMRALGFKI----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9VXY5-1", "uniprot_id": "Q9VXY5_DROME", "id": "Q9VXY5-1", "name": "Cytochrome c oxidase copper chaperone", "aln": "MGNSASQGVAAPSVSAAHPLTTASAATASTTTASAATASGEKPKCKACCACPETKRARDACIVENGE--ENCLALIEAHKKCMRDAGFNI----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12287-1", "uniprot_id": "COX17_YEAST", "id": "Q12287-1", "name": "Cytochrome c oxidase copper chaperone", "aln": "----------MTETDKKQE---------------QENHAECEDKPKPCCVCKPEKEERDTCILFNGQDSEKCKEFIEKYKECMKGYGFEVPSAN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : *.**.* *. **:**: :*: *:* :** :*:**: **:: ", "identical_positions": 19, "similar_positions": 17, "identity": "20.21%" }, { "cls_id": "homologset.agr.MGI:1333807", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9PTL1-1", "uniprot_id": "E9PTL1_RAT", "id": "E9PTL1-1", "name": "Cell cycle checkpoint protein RAD17", "aln": "---MSETFLRPKVSSTKVTDWVDPAFDDFSANTAVTTITVSSLSLNNSSHRRKYLPSTLESNRLSARKRGRLP-LEQTNGLETSKEYLSDDEPWVDKYKPETQHELAVHKKKIEEVETWLKTQVLEVKPKHGGSILLITGPPGCGKTTTIKILSKELGIQVQEWVNP-ILQDFQKDD-YKELFNSESNFSVIPYQSQIAVFNDFLLRATKYNKLQMLGDALTTDKKIILVEDLPNQFYRD-ANALHEILRKYVHIGR---CPLVFIVSDSVS-GDSNHR------------LLFPKNIQEECSVSNISFNPVAPTIMMKFLNRIVTIEASKNGEKITVPNKASLELLCQGCSGDIRSAINSLQFSSSKG---ENSSWSKKKKMSLKSDASISKAKQKRKHNSTLENQEIQAIGGKDVSLFLFRALGKILYCKRAPLTELASPRLPAHLSEHDRDTLLVQPEEIVEMSHMPGEFFNLYLHQNYIDFFTDVDDLVRASEFLSFADILGGDWNTRSSLRDYSTSIAARGVMHSNTSRRFAHCQGGGSSFRPLHKPQWFLIQKKYRENCLAAKALFCDFCLPAVCLQTQLLPYLALLTIPMRNKAQISFIQDIGRLPLKRNFGRLKMEALTDRELGLIDPDSGDELLHSGGQPAQEAQG---QPAQTADPETWSLPLSQNSGSDLPASQPRPFSSKVDLEEEEEEEEDIVIEDYDSDET", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6NXW6-1", "uniprot_id": "RAD17_MOUSE", "id": "Q6NXW6-1", "name": "Cell cycle checkpoint protein RAD17", "aln": "---MSETFLRPKVSSTKVTDWVAPAFDDFEANTAITTITASSLTFSNSSHRRKYLPSTLESNRLSARKRGRLS-LEQTHGLETSRERLSDNEPWVDKYKPETQHELAVHKKKIEEVETWLKAQVLEVKPKQGGSVLLITGPPGCGKTTTIKILSKELGIQVQEWVNP-ILPDFQKDD-YKELLSLESNFSVVPYQSQIAVFNDFLLRATKYSKLQMLGDDLTTDKKIILVEELPNQFYRD-PNALHEILRKHVQIGR---CPLVFIVSDSVS-GDNNQR------------LLFPRNIQEECSVSNISFNPVAPTIMMKFLNRIVTIEASKNGEKIIVPNKTSLELLCQGCSGDIRSAINSLQFSSSKG---ENSSWSKKKRMSLKSDAAISKSKQKKKHNSTLENQEIQAIGGKDVSLFLFRALGKILYCKRAPLTELDSPRLPAHLSEHDRDTLLVQPEEIVEMSHMPGDFFNLYLHQNYIDFFAEVDDLVPASEFLSFADILGGDWNTRSLLREYSTSVATRGVMHSNKARGFAHCQGG-SSFRPLHKPQWFLIQKKYRENCLAAKALFVDFCLPALCLQTQLLPYLALLTIPMRNKAQISFIQDVGRLPLKRSFGRLKMEALTDRELGLIDPDSGDESPHSGGQPAQEAPGEPAQAAQNADPETWSLPLSQNSGSDLPASQPQPFSSKVDMEEEEEEEEDIIIEDYDSEET", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75943-1", "uniprot_id": "RAD17_HUMAN", "id": "O75943-1", "name": "Cell cycle checkpoint protein RAD17", "aln": "---MSKTFLRPKVSSTKVTDWVDPSFDDFLECSGVSTITATSLGVNNSSHRRKNGPSTLESSRFPARKRGNLSSLEQIYGLENSKEYLSENEPWVDKYKPETQHELAVHKKKIEEVETWLKAQVLERQPKQGGSILLITGPPGCGKTTTLKILSKEHGIQVQEWINP-VLPDFQKDD-FKGMFNTESSFHMFPYQSQIAVFKEFLLRATKYNKLQMLGDDLRTDKKIILVEDLPNQFYRD-SHTLHEVLRKYVRIGR---CPLIFIISDSLS-GDNNQR------------LLFPKEIQEECSISNISFNPVAPTIMMKFLNRIVTIEANKNGGKITVPDKTSLELLCQGCSGDIRSAINSLQFSSSKG---ENNLRPRKKGMSLKSDAVLSKSKRRKKPDRVFENQEVQAIGGKDVSLFLFRALGKILYCKRASLTELDSPRLPSHLSEYERDTLLVEPEEVVEMSHMPGDLFNLYLHQNYIDFFMEIDDIVRASEFLSFADILSGDWNTRSLLREYSTSIATRGVMHSNKARGYAHCQGGGSSFRPLHKPQWFLINKKYRENCLAAKALFPDFCLPALCLQTQLLPYLALLTIPMRNQAQISFIQDIGRLPLKRHFGRLKMEALTDREHGMIDPDSGDEAQLNGGHSAEESLG---EPTQATVPETWSLPLSQNSASELPASQPQPFSAQGDMEEN------IIIEDYESDGT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2BGQ6-1", "uniprot_id": "A2BGQ6_DANRE", "id": "A2BGQ6-1", "name": "", "aln": "--MMSKLSLGGKQSSGKINNWVEPSFGELLG------------GVSRSLKKGPLSGESKTAEKKSRKRKVDPYVSDNQITVSSEANNPDQDEPWVDIHAPQSQAELAVHKKKVEEVESWLRVHLD--KSKKGGAILLLTGPSGCGKTATVQVLAKELGFQVQEWSNPSTTSQYKTEDLFTQSFDPDSRFNRFHGSSQTGLFQEFLLRANKYSRLRMSGETWTEDRKIILIEEFPNQFYRQ-PGCLHDILRQFIKCGR---CPLVLIVSDSLS-GDKNSR------------LLF-KDVLQELGIHNISFNPVAPTSMMKVLSRIVTIEAVKSSGRISVPDKAALDLLCSGSSGDIRSAINSLQFSSFTDNSLERRLWASKKGKSSSAKPAVKAKGRSKSSKSKDMQDESPAIGGKDASLFLFRALGKILYCKRESYEGTQAPKLPPHLTDHQRDRLLVDPELVIERSHMSGEFFNLYLHQNYPDFFSDVEDIAQASEYLSDADFLTAEWSSRSTMLEYGSSVATRGLMHSNSSRAQANSQST-AGFKPLHKPHWLHINKTYRENYQTAQSLFLSFCLTPVSLLTEMVPYLAKLTNPMRNQAQIAFIQNFGHLSQKRVTGRLRLEALGDKDPGILDADSENE---DSCAAQSLDPG----TTQANATTESNLPNSQDPSGELSASQPQPTSTEALLDEE-----DLLIEEYDSD--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O96532-1", "uniprot_id": "O96532_DROME", "id": "O96532-1", "name": "", "aln": "MSVRKKTWVRCAFSEMNLTTSPAPSESTPAKRTR-----SASNVSSSRVSRSRTPSINTKPIQIPDVDSVDLTAMDDDQDADITVPPPEVKENWMESFEPATSDDLAVHPKKVGELRDWLR-HCEAVRKKFPAQMCLLTGPTGAGKTTTLRVLAKEFGYQLQEWINPIDCEVVNTLG--------DQTTGASYVGSHLEAFKSFLLRASRYKSLLDS-----QNKRLLLVEDFPNVLLSDKEVNFEELLEEYTAYGK---SPLVFIVADAKSRGLNISY------------RLFPDQLKAKHRIEHISFNAIASTIMQKSMKTFCSVMQ-QNKATYKVPSTAVVDSIVVGAQGDIRNALINLHLSSLKG---------VSSMPTKQLNVSVSAKGRKKKMQSTLKS------IGRDESITLMHALGRVLNPKFN-----------------EDKTMLHSPEEITEAFNTEPRNFVNFVYANYLPHFKEIDDVVTAINDLGLSDCMLNEYRD-DNLSVMGLNVAIRGVMMSNTCPVSG----------------WMPVRGPKRIN-----------------------------------------IQPQATLAEQRLVG-------------------------------VGYAG----IARTLYATEYSSLVKLIAGKPVDTTSSQSTDSKQDF--------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32641-1", "uniprot_id": "RAD24_YEAST", "id": "P32641-1", "name": "Checkpoint protein RAD24", "aln": "------------MDSTNLNKRPLLQYS---------------LSSLGSQITKWSSSRPTSPVRKARSTENDFLSKQDTSSILPSIND-DGGEQWYEKFKPNCLEQVAIHKRKLKDVQEALDAMFLPNAKHR---ILLLSGPSGCSKSTVIKELSKILVPKYRQNSNGTSFRSTPNEH-------KVTEFRGDCIVNDLPQMESFSEFLKGARYLVMS------NLSLILIEDLPNVFHIDTRRRFQQLILQWLYSSEPLLPPLVICITECEIPENDNNYRKFGIDYTFSAETIMNKEILMHPRLKRIKFNPINSTLLKKHLKFICVQNMKMLKEKNKWNKRQEVIDYIAQETGDIRSAITTLQFWATSSGSLPISTRESTISYFHAIGKVIHGSHSTNNDNEMINNLFENSNNLLSKEDFKLGILENYNTFNKGEFSISDASSIVDCLS--ECDNMNGLPESNEYGLREVRKTFRNISKQGHNHGTVYFPREWKVRKLQNSFKVQAEDWLNVSLYKYNAVHSFRNITLEFGYYAPLIRKCQSYKKKYILYYLKNLPSGSSGPKQTMDKFSDIMKVENGIDVVDRIGGPIEALSVEDGLAPLMDNDSNNCDHLEDQKKERDRRLRMLIDQYERNVMMANDDLEDEETSFNDDPIVD---SDSDNSNNIGNETFGRSDEDESLCEILSQRQPRKAPVISESLSDSDLEIL-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. ::. . . : . :: . * * : . * ::*:* :*: ::. * : : *::**.*..*::.:: *:* : :: * . .. ::.* . * : ::*:*::** : : :.::: : .. **:: :::. . :: :: . : .*.**.: .* : * :. : . : ****.*: .*:: : .. . : .. . . . . : * . : : . : ** . * .: . . : . . :: . . . : . : : : * :: . : . : .: : . ", "identical_positions": 39, "similar_positions": 135, "identity": "5.45%" }, { "cls_id": "homologset.agr.MGI:1333808", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4AD59-1", "uniprot_id": "D4AD59_RAT", "id": "D4AD59-1", "name": "Olfactory receptor", "aln": "MESGNDTQLSEFFLLGFSEKQPEIQPLIFGLFLSMYLVTVTGNLLIIVAIIVDAHLHTPMYIFLSNLSFVDICFTSTTVPQMLVNIHTQSKVITYAGCITQMYFLLLFSGLDIFLLTVMAYDRYVAICHPLHYMIIMNTRRCGLLILACWIIGVLNSLLHSFLVLRLSFCTNLEIPHFFCELNQVVHQACSDTFINDMVIYITAMLLAVGPLSGILYSYSKIVSSIRAISSAQGKYKAFSTCASHLSVVSLFYCTLLGVYLSSAVTQNSHATATASLMYTVVTPMLNPFIYSLRNKDIKTALKILLGSVTRSRLMDSPS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VGU7-1", "uniprot_id": "Q8VGU7_MOUSE", "id": "Q8VGU7-1", "name": "Olfactory receptor", "aln": "METGNDTQLSEFFLLGFSENQPQIQPVIFGLFLFMYILTFTGNLLIIMAIIVDSHLHTPMYLFLSNLSFVDICFTSTTVPQMLVNIHTQSKAITYAGCIIQMYFLLLFSGLDIFLLTVMAYDRYVAICHPLHYMIIMSTRRCGLMILACWIIGVINSLLHTFLVLRLSFCTNLEIPHFFCELNQVVHQACSDTFLNDMVIYITAMLLAVGPFSGILYSYSRIVSSICAISSVQGKYKAFSTCASHLSVVSLFYCTLLGVYLSSAVTQNSHATATASLMYTVVTPMLNPFIYSLRNKDIKTALKILLGSVTRSRSMDSPS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O76100-1", "uniprot_id": "OR7AA_HUMAN", "id": "O76100-1", "name": "Olfactory receptor 7A10", "aln": "MKSWNNTIILEFLLLGISE-EPELQAFLFGLFLSMYLVTVLGNLLIILATISDSHLHTPMYFFLSNLSFVDICFVSTTVPKMLVNIQTHNKVITYAGCITQMCFFLLFVGLDNFLLTVMAYDRFVAICHPLHYMVIMNPQLCGLLVLASWIMSVLNSMLQSLMVLPLPFCTHMEIPHFFCEINQVVHLACSDTFLNDIVMYFAVALLGGGPLTGILYSYSKIVSSIRAISSAQGKYKAFSTCASHLSVVSLFYGTCLGVYLSSAATHNSHTGAAASVMYTVVTPMLNPFIYSLRNKHIKGAMKTFFRGKQ---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O14581-1", "uniprot_id": "OR7AH_HUMAN", "id": "O14581-1", "name": "Olfactory receptor 7A17", "aln": "MEPENDTGISEFVLLGLSE-EPELQPFLFGLFLSMYLVTVLGNLLIILATISDSHLHTPMYFFLSNLSFADICFISTTIPKMLINIQTQSRVITYAGCITQMCFFVLFGGLDSLLLAVMAYDRFVAICHPLHYTVIMNPRLCGLLVLASWMIAALNSLSQSLMVLWLSFCTDLEIPHFFCELNQVIHLACSDTFLNDMGMYFAAGLLAGGPLVGILCSYSKIVSSIRAISSAQGKYKAFSTCASHLSVVSLFCCTGLGVYLTSAATHNSHTSATASVMYTVATPMLNPFIYSLRNKDIKRALKMSFRGKQ---------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:. *:* : **.***:** :*::*..:***** **::*. ******:* * *:*******:*******.**** ***:*:**:**:*:.:.******* ** *::** *** :**:******:********* :**..: ***::**.*::..:**: ::::** *.***.:********:***:* ******:**: :*::. **. **: *** ***:***** ****.******************** * *****:**.*:***: *:**:****.**************.** *:* : . ", "identical_positions": 201, "similar_positions": 75, "identity": "63.01%" }, { "cls_id": "homologset.agr.MGI:1333809", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4AEH8-1", "uniprot_id": "D4AEH8_RAT", "id": "D4AEH8-1", "name": "Sphingosine 1-phosphate receptor 4", "aln": "MNISTWSTLVTPESCHRLAASGHSLLIVLHYNHSGRLASRGGPEDNGGLGMLRGPSVAAGCLVVLENAMVLAAIAIHMRSR-RWVYYCLLNITLSDLLTGLAYVVNVLLSGTRTFQLSPVHWFLREGLLFMALAASTFSLLFTAGERFATMVR-VAESGATKTSRVYGCIGLCWLLAATLGLLPLLGWNCVCAFQRCSSLLPLYSKGYVLFCVVVFALILVTILSLYGAIFRVVRANGQKSPRPPARRKSRRLLNTVLMILVAFVVCWGPLFGLLLADIFGSNVWAQEYLRGMDWILALAVLNSAINPLIYSFRSREVQHAVLTFLCCGCLRLGLRGPGDCLTRITEAHSGASTTDSSLRPRDSFRTSRSLSFK--------MREPLSSVSSIRSA---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z0L1-1", "uniprot_id": "S1PR4_MOUSE", "id": "Q9Z0L1-1", "name": "Sphingosine 1-phosphate receptor 4", "aln": "MNISTWSTLVTPESCHRLAASGHSLLIVLHYNHSGRLASRGGSEDGGGLGMLRGPSVAAGCLVVLENAMVLAAIAIYMRSR-RWVYYCLLNITLSDLLTGLAYVVNVLLSGTRTFQLSPVHWFLREGLLFMALAASTFSLLFTAGERFATMVR-VAESGATKTSRVYGCIGLCWLLAAILGLLPLLGWNCVCAFPRCSSLLPLYSKGYVLFCVVVFALILVAILSLYGAIFRVVRANGQKSPRPPARRKSRRLLNTVLMILVAFVVCWGPLFGLLLADIFGSNVWAQEYLRGMDWILALAVFNSAINPLIYSFRSREVQRAVLAFLCCGCLWLGLRGPGDCLTRITEAHSGASTTDSSLRPRDSFRTSRSLSFR--------MREPLSSISSVRST---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95977-1", "uniprot_id": "S1PR4_HUMAN", "id": "O95977-1", "name": "Sphingosine 1-phosphate receptor 4", "aln": "MNAT--GTPVAPESCQQLAAGGHSRLIVLHYNHSGRLAGRGGPED-GGLGALRGLSVAASCLVVLENLLVLAAITSHMRSR-RWVYYCLVNITLSDLLTGAAYLANVLLSGARTFRLAPAQWFLREGLLFTALAASTFSLLFTAGERFATMVRPVAESGATKTSRVYGFIGLCWLLAALLGMLPLLGWNCLCAFDRCSSLLPLYSKRYILFCLVIFAGVLATIMGLYGAIFRLVQASGQKAPRPAARRKARRLLKTVLMILLAFLVCWGPLFGLLLADVFGSNLWAQEYLRGMDWILALAVLNSAVNPIIYSFRSREVCRAVLSFLCCGCLRLGMRGPGDCLARAVEAHSGASTTDSSLRPRDSFRGSRSLSFR--------MREPLSSISSVRSI---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QC10-1", "uniprot_id": "F1QC10_DANRE", "id": "F1QC10-1", "name": "", "aln": "MEVLR--SFSSASSCPDVYNWTSNSLILEHYNYTGRLHHRKPSKK--SVSAVTVLFLCFSVFIILENLMVLLAVLFRVRLRHRWIFICIANIALSDLLTGTSYVVNICMSGEQTFRLTPILWLFREGLLFVALAASIFSLLLIAVERYATMMKPVHQKTATKTYRVYIMMLLCWITAFIIGFLPLMGWNCVCDLRSCSTLLPLYSKSYILFALVIFFIILLTIGVLYFAIYCHVRSS-TETISARSRKRSLRLLKAVISIVGVFMVCWGPLFILLLVDFFCYSRSCSPLFN-PEWVIALAVLNSAMNPLIYSFGSLELRKAIATLLCCSCLKAGLCDPKTFMSKETSSTSGS--RHSSLR--NSFSKVRNLSTSPPPEPKNGKKTRLSSTTSCLSASSG", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: : :..** : . **: ***::*** * .:. .:. : :. . :::*** :** *: :* * **:: *: **:******* :*:.*: :** :**:*:* *::****** ***** ****: * **:***:: * :. **** *** : ***: * :*:***:****:* : **:******* *:**.:*:* :* :* ** **: *::. :: . :*::: ***::*: *: .*:******* ***.*.* . .. :. :*::****:***:**:**** * *: :*: ::***.** *: .* ::: ..: **: .**** :** *.** : *** :* * ", "identical_positions": 163, "similar_positions": 110, "identity": "40.85%" }, { "cls_id": "homologset.agr.MGI:1333811", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M6S6-1", "uniprot_id": "F1M6S6_RAT", "id": "F1M6S6-1", "name": "Methyl-CpG-binding domain protein 1", "aln": "----MAEAWQDCPALGPGWKR---REAFRKSGASCGRSDIYYRSPTGEKIRSKIELTRYLGPACDLTLFDFRQGILCHPVPKTHPLAVP------SKKKKKTSKPAKAKKQQVGPQRSEVRKETPREGNKVAPATALLPVTASAPAPVPVPVSAPAPAPAPLCCENCGIHLSWDGIKRERRRTLCKDCRAQRIAFNREQRMFKRVGCGECTACL--VKEDCGVCSICCLQLPNDVASGLFCKCEQRRCLRIVEKNRGCGVCRGCQTQEDCGHCRICLRFPRPGLKRQWRCLQRRCFWGKYDHSKRG--PRVASRRHSRAPP--LPPHAASQHPEPTELHIS----DQTPTAPAEFVYDCVE---EDE--LQPYTNQRQNRKCGACAACLRRMDCGHCDFCCDKPKFGGSNQKRQKCRWRQCLQFAMKRLLPSIGPGSEEEARLLP---HHTHQK----RSASTRQLQLSSPLKAPLAVVTTPPGPVQDSGKRQAGS-----------GFVLPQPDTDLVYLQEGTSSLMQVPGPAAASTENP-------AQETQGSAPGWVVALPQVKQEK--ADAPEEWTAVTTFLTSSTVQPGFLSKASGLDPPPVKREPPGPEEDGEENKEDDVSESAPAEEIGGIG-------------TPVITEIFSLGGTRLRDAE-----------------------------------AWLPRLHKLLAVNENEYFTELQLKEEIL----------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z2E2-1", "uniprot_id": "MBD1_MOUSE", "id": "Q9Z2E2-1", "name": "Methyl-CpG-binding domain protein 1", "aln": "----MAESWQDCPALGPGWKR---RESFRKSGASFGRSDIYYQSPTGEKIRSKVELTRYLGPACDLTLFDFRQGTLCHPIPKTHPLAVP------SKKKKKPSKPAKTKKQQVGLQRSEVRIETPQGEYKAPTATALASLSVSASASSSASASASASSHAPVCCENCGIHFSWDGVKRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGDCAACL--VKEDCGVCSTCRLQLPSDVASGLYCKCERRRCLRIMEKSRGCGVCRGCQTQEDCGHCCICLRSPRPGLKRQWRCLQRRCFWGKRDSSKRG--SKVASQRHSQAPP--LPPHPASQYTEPTELHIS----DIAPTSPAEFIYYCVD---EDEDELQPYTNQRQNRKCGACAACLRRMDCGRCDFCCDKPKFGGGNQKRQKCRWRQCLQFAMKRLLPSAGSGSGEGAGLRPYQTHQTHQK----RPASARQLQLSSPLKAPWAVVTAPPGPVRDSRKQQAGR-----------GSVLPQPDTDFVFLQEGTSSAMQMPGTAAASTEVP-------VQAAQCSAPSWVVALPQVKQET--ADAPEEWTAVTTFLTSSTLQSGFPSKAADPDLSPVKQEPPGPEEDGEE-KKDDVSETTPAEEIGGVG-------------TPVITEIFSLGGTRLRDAE-----------------------------------AWLPRLHKLLAVNEKEYFTELQLKEEVL----------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UIS9-1", "uniprot_id": "MBD1_HUMAN", "id": "Q9UIS9-1", "name": "Methyl-CpG-binding domain protein 1", "aln": "----MAEDWLDCPALGPGWKR---REVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLTLFDFKQGILCYPAPKAHPVAVA------SKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADTDT------------------APASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECAACQ--VTEDCGACSTCLLQLPHDVASGLFCKCERRRCLRIVERSRGCGVCRGCQTQEDCGHCPICLRPPRPGLRRQWKCVQRRCLRGKHARRKGGCDSKMAARRRPGAQP--LPPPPPSQSPEPTEPHPR----ALAPSPPAEFIYYCVD---EDE--LQPYTNRRQNRKCGACAACLRRMDCGRCDFCCDKPKFGGSNQKRQKCRWRQCLQFAMKRLLPSVWSESEDGAGSPP---PYRRRK----RPSSARRHHLGPTLKPTLATRTAQPDHTQAPTKQEAGG-----------GFVLPPPGTDLVFLREGASSPVQVPGPVAASTEAL-------LQEAQCSGLSWVVALPQVKQEK--ADTQDEWTPGTAVLTSPVLVPGCPSKAVDPGLPSVKQEPPDPEEDKEENKDDSASKLAPEEEAGGAG-------------TPVITEIFSLGGTRFRDTA-----------------------------------VWLPRSKDLKKPGARKQ---------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7SZX5-1", "uniprot_id": "Q7SZX5_DANRE", "id": "Q7SZX5-1", "name": "", "aln": "--MDTEEVAAEAPAETATEEKDATSEENKESTTSTDIQDHVTDKNQEEDAAAKEDEEAVIDKEAEEAVIQKKDEEAVVQKEGEEAIIQKEGEETIAEKEGEETVTEKEGEDAVTEKEGEEAETEKEGEDAVTEKDGEDAVTEKEGKDAVTEKEGEDAVTEKEGKDAVTEKEGEDAVTEKEGEEAETENKGEEAVLEKQDESSKDVDNPSCDWLEP-LEEDCEDVDSQSVDGEVESVAGSEFSGSVVLKSTGDRGGRGAGRAR-RKTQFEADEGWEDWPALGKGWKRKEVFRRSGTSEGRSDTYYISPRGRKVRSRVELTKH--IGHSVDLTNFDFKSGQFLGEGARRKPRVRRKMESPLAQ---PETSLTLSVRSDSADVQRPASSAGFATAQK-KSLHSTQNPPYATTASNLSTFVSPGTNKSSLSATTQPVVDLTEDAANPTPPVVSVASEKPV--NGASGGPRRLFGVCIRCNKTYSYEEGQTLCKDCRIENR-----------ALASRKPYKKWVPCGRCWACQTTVDCGKCVSCRNGRLRHRLNIHSRKVVKCRKRKCLHPVRRERGFKDSEGQFSNMESSMSTEPSVSEDYDESQSSYLQYSDSEDLSVFFEGNDGDNGLDEMGVPKVRRRSCGKCKGCVRRTDCGTCDFCMDKPKFGGRNKKRQK-----------------------------------CRLRQCTREAMVGFFYTITFIHME--------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A2R8Q213-1", "uniprot_id": "A0A2R8Q213_DANRE", "id": "A0A2R8Q213-1", "name": "", "aln": "MTDELNELSPESEILKPEDAVPAYLNEMHPIGEDVDSDVEDDDMSCKVTVELLPDWLKPMEEEEVGVDELMSAGRINRRKTKEKPPKVKRGRGRPPKIRHGLSRSEFKKGLHADRTMKKKRVGSLMSRKRLSRKATSVPDPSLKAEVLPRTRQRVVRSSTSTPQSTKQVPDSPAGGTSAEFNSPPRLTRVSPPSIDTSRRSFVHSPSVKVGNVTQQIISTEPGKDVSELPLQLWLCPSLEPISPTQTQEILSQQTVGSPNFPEASLNGTMTVKESLTMTVKESLPLLSECEGCGCPFSAQKHGDTLCYRCRIKREKKRSPPNILCRKVRQDQWEVEKEKHPRKQMLQRPQRYGKTENDIVPDGGDDDDEEYWRLKKRNRRMCQRCDACRRDTDCGKCDFCMDKPKFGGSNKKRQKCRLRQCKFQSKLQFRNGMKGVPTSSLSPIKKMIKSNKLLKIKKRGRPRKKKFKNDPWEEEEEDYEVSDNDEDDQELRSSEMNGSQVRKHGKWSYTFKEDEDDAAYVEDVVDANIEEDSVILDNERSVMASNEMYNTTSGLSSQGLYYNVSGMPLSSHLIGSAPICNSGAVAMGEVIGSVPMADEMSQNGFLQIEMVKVGSSPSHYREEQQNTQQMHIADPQQEHT--------------PVITQIFSLAGPETESDRDPGLIELFTSLGQSVLPAHWVCVIAKGPVLQLLQCSKLSTMADTVVQIEKGFFYQVTVQNQPLLLMHSLYSRHPTCLEKVEHVVSLLLDLEALGVCQGYQNFQMCSPWEPKMCVRAALCDLLIPKDDEHCGKCSQPVEG", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :. . : : . . : : . .. .: . : . . : . . . . . : . :: . . . : . . : .. . *. . : . . . : : : . : * : . : . . * : :. .. ::* :. .: .. : . . . . . : . . . . . . . : : . .: . : .: . . . .. . . : .:.* . . * ", "identical_positions": 7, "similar_positions": 103, "identity": "0.86%" }, { "cls_id": "homologset.agr.MGI:1333812", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F7EY92-1", "uniprot_id": "F7EY92_RAT", "id": "F7EY92-1", "name": "", "aln": "--------MERKRWECPALPQGWEREEVPRRSGLSAGHRDVFYYSPSGKK-----------FRSKPQLARYLGGSMDLSTFDFRTGKMLMNKMNK--------------------------------SRQRVRYDSSNQVKAL-----------AKHLPGPSNPSWTPVGAARCRVFSPQGKPDLNTALPVRQTASIFKQPVTKITNHPSN--KVKSDPQK-AVDQPRQLFWEKKLSGLSAFDIAEELVRTMDLPKGLQGVGPGCTDETLLSAIASALHTSTLPITGQLS--AAVEKNPGVWLNTAQPLCKAFMVTDDDIRKQEELVQQVRKRLEEALMADMLAHVEELARDGEAPLDKACAEEEEEEEEEEEEE-----PEPERV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z2D8-1", "uniprot_id": "MBD3_MOUSE", "id": "Q9Z2D8-1", "name": "Methyl-CpG-binding domain protein 3", "aln": "--------MERKRWECPALPQGWEREEVPRRSGLSAGHRDVFYYSPSGKK-----------FRSKPQLARYLGGSMDLSTFDFRTGKMLMNKMNK--------------------------------SRQRVRYDSSNQVK---------------------------------------GKPDLNTALPVRQTASIFKQPVTKITNHPSN--KVKSDPQK-AVDQPRQLFWEKKLSGLSAFDIAEELVRTMDLPKGLQGVGPGCTDETLLSAIASALHTSTLPITGQLS--AAVEKNPGVWLNTAQPLCKAFMVTDDDIRKQEELVQQVRKRLEEALMADMLAHVEELARDGEAPLDKACAEEEEEEEEEEEE------PEPERV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95983-1", "uniprot_id": "MBD3_HUMAN", "id": "O95983-1", "name": "Methyl-CpG-binding domain protein 3", "aln": "--------MERKRWECPALPQGWEREEVPRRSGLSAGHRDVFYYSPSGKK-----------FRSKPQLARYLGGSMDLSTFDFRTGKMLMSKMNK--------------------------------SRQRVRYDSSNQVK---------------------------------------GKPDLNTALPVRQTASIFKQPVTKITNHPSN--KVKSDPQK-AVDQPRQLFWEKKLSGLNAFDIAEELVKTMDLPKGLQGVGPGCTDETLLSAIASALHTSTMPITGQLS--AAVEKNPGVWLNTTQPLCKAFMVTDEDIRKQEELVQQVRKRLEEALMADMLAHVEELARDGEAPLDKACAEDDDEEDEEEEEEEPDPDPEMEHV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58IDT6-1", "uniprot_id": "A0AC58IDT6_DANRE", "id": "A0AC58IDT6-1", "name": "", "aln": "--MAVLSRTSRIRHDCSFFSRGEEEEEEQRRERGEAGR--LYSLCPTGKK-----------FRSKPQLARYLGNSMDLSSFDFRTGKMLMSKLNK--------------------------------NRQRPRYDNNSQSK---------------------------------------GKPDLNTSLPVRQTASIFKQPVTKVTNHPSN--KVKTDPQK-AIDQPRQLFWEKKLSGLNAFDIAEELVKTMDLPKGLQGVGPGCTDKTLLSAIASALHTSAAPITGQLS--AAVEKNPGVWLNTAQPLCKAFIVTDEDIRKQEELVYSVRKRLEEALMADMLAHVEETASEGEALKQEGNCTDEKQEV-----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KGZ0-1", "uniprot_id": "A0A0B4KGZ0_DROME", "id": "A0A0B4KGZ0-1", "name": "", "aln": "MQMNPSVTIERKRVDCSVLPKGWQRDEVRKSGSSANNNASSNNNSSATASSNNNNNKVDVFYYSSPTGKRAEGKPQDIAIPDFQPGKMPHCALPSPSISLYRCSAMPLPIASGGGNGATSGSAANALKRKFARSQGGNAAGAAGAAPPAATASSAATATAASASPSTANRQQQQIELSRALRTDVSLVPPIRQTASIFKQPVTVIRNHKQDPAKAKNEPKHGTREKPKQLFWEKRLERLRACHDSGEELDDISLPKTIRTVGPNVNEQTVLQSVATALHMLNAGVHGQSSTKADLTKNAMAFMNPEQPLMHAVIISEDDIRKQEDRVGVARRKLQDALKT----------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* * :*. :.:* :.:* : .. ..: . : *.* * * . *:: **:.*** : . .*: * :... :.*:. *:************ : ** .: *.*.:*:: : ::*:******:*. * * . : * : :.*** :: ***. .::*:*.::*:*** : ** * * : **. .::*. *** :*.:::::******: * .*::*::** : ", "identical_positions": 81, "similar_positions": 87, "identity": "20.98%" }, { "cls_id": "homologset.agr.MGI:1333813", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A986-1", "uniprot_id": "D4A986_RAT", "id": "D4A986-1", "name": "", "aln": "MRAHPGGGRCCPEQEEGESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRGRGRWKQAARGGGVCGRGRGRGRGRGRGRGRGRGRGRPQSGGSGLGGDGG--AGGCGVGSSGGVAPRRDPVPFPSGSSGPGPRGPRATESGKRMDCPALPPGWKKEEVIRKSGLSAGKSDVYYFSPSGKKFRSKPQLARYLGNAVDLSSFDFRTGKMMPSKLQKNKQRLRNDPLNQNKGKPDLNTTLPIRQTASIFKQPVTKVTNHPNN--KVKSDPQR-MNEQPRQLFWEKRLQGLSASDVTEQIIKTMELPKGLQGVGPGSNDETLLSAVASALHTSSAPITGQVS--AAVEKNPAVWLNTSQPLCKAFIVTDDDIRKQEERVQQVRKKLEEALMADILSRAVDTEEVDIDMDSGDEE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z2E1-1", "uniprot_id": "MBD2_MOUSE", "id": "Q9Z2E1-1", "name": "Methyl-CpG-binding domain protein 2", "aln": "MRAHPGGGRCCPEQEEGESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRGRGRWKQAARGGGVCGRGRGRGRGRGRGRGRGRGRGRPQSGGSGLGGDGGGGAGGCGGGSGGGVAPRRDPVPFPSGSSGPGPRGPRATESGKRMDCPALPPGWKKEEVIRKSGLSAGKSDVYYFSPSGKKFRSKPQLARYLGNAVDLSSFDFRTGKMMPSKLQKNKQRLRNDPLNQNKGKPDLNTTLPIRQTASIFKQPVTKFTNHPSN--KVKSDPQR-MNEQPRQLFWEKRLQGLSASDVTEQIIKTMELPKGLQGVGPGSNDETLLSAVASALHTSSAPITGQVS--AAVEKNPAVWLNTSQPLCKAFIVTDEDIRKQEERVQQVRKKLEEALMADILSRAADTEEVDIDMDSGDEA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UBB5-1", "uniprot_id": "MBD2_HUMAN", "id": "Q9UBB5-1", "name": "Methyl-CpG-binding domain protein 2", "aln": "MRAHPGGGRCCPEQEEGESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRGRGRWKQAGRGGGVCGRGRGRGRGRGRGRGRGRGRGRPPSGGSGLGGDGG---GCGGGGSGGGGAPRREPVPFPSGSAGPGPRGPRATESGKRMDCPALPPGWKKEEVIRKSGLSAGKSDVYYFSPSGKKFRSKPQLARYLGNTVDLSSFDFRTGKMMPSKLQKNKQRLRNDPLNQNKGKPDLNTTLPIRQTASIFKQPVTKVTNHPSN--KVKSDPQR-MNEQPRQLFWEKRLQGLSASDVTEQIIKTMELPKGLQGVGPGSNDETLLSAVASALHTSSAPITGQVS--AAVEKNPAVWLNTSQPLCKAFIVTDEDIRKQEERVQQVRKKLEEALMADILSRAADTEEMDIEMDSGDEA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4KGZ0-1", "uniprot_id": "A0A0B4KGZ0_DROME", "id": "A0A0B4KGZ0-1", "name": "", "aln": "MQMNPS---VTIERKRVDCSVLPKGWQRDEVRKSGSSANNNASSNNNSSATASSNNNNNKVDVFYYSSPTG-------------------KRAEGKPQD------------------------------IAIPDFQPGKMPHCALPSPSISLYRCSAMPLPIASGGGNGATSGSAANALKRKFARS-----QGGNAAGAAGAAPPAATASSAATATAASASPSTANRQQQQIELSRALRTDVSLVPPIRQTASIFKQPVTVIRNHKQDPAKAKNEPKHGTREKPKQLFWEKRLERLRACHDSGEELDDISLPKTIRTVGPNVNEQTVLQSVATALHMLNAGVHGQSSTKADLTKNAMAFMNPEQPLMHAVIISEDDIRKQEDRVGVARRKLQDALKT----------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: :*. *::. :.:. .* *.. :.*.... *.* .. .:..... . : :. * *..*:* . :.:*. ..* *: . .: * . *.*:* . :. **.:: *: * . : * * : :: . : .* .. :* ::: .. :.*:. . ************** . ** .: *.*.:*:: .*:*:********: * *.. : : :. :.*** :: ***. *::*:*.:**:*** .* : ** * * : **. .::*..*** :*.*::::******:** .*:**::** : ", "identical_positions": 99, "similar_positions": 128, "identity": "23.63%" }, { "cls_id": "homologset.agr.MGI:1333815", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P35411-1", "uniprot_id": "CX3C1_RAT", "id": "P35411-1", "name": "CX3C chemokine receptor 1", "aln": "MPTSFPELDLENFEY-------DDSAEACYLGDIVAFGTIFLSIFYSLVFTFGLVGNLLVVLALTNSRKSKSITDIYLLNLALSDLLFVATLPFWTHYLISHEGLHNAMCKLTTAFFFIGFFGGIFFITVISIDRYLAIVLAANSMN-NRTVQHGVTISLGVWAAAILVASPQFMFTKRKDNE-----CLGDYPEVLQEIWPVLRNSEVNILGFVLPLLIMSFCYFRIVRTLFSCKNRKKARAIRLILLVVVVFFLFWTPYNIVIFLETLKFYNFFPSCGMKRDLRWALSVTETVAFSHCCLNPFIYAFAGEKFRRYLRHLYNKCLAVLCGRPVHAGFST-ESQRSRQDSILSS-LTHYTSEGEGSLLL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z0D9-1", "uniprot_id": "CX3C1_MOUSE", "id": "Q9Z0D9-1", "name": "CX3C chemokine receptor 1", "aln": "MSTSFPELDLENFEY-------DDSAEACYLGDIVAFGTIFLSVFYALVFTFGLVGNLLVVLALTNSRKPKSITDIYLLNLALSDLLFVATLPFWTHYLISHEGLHNAMCKLTTAFFFIGFFGGIFFITVISIDRYLAIVLAANSMN-NRTVQHGVTISLGVWAAAILVASPQFMFTKRKDNE-----CLGDYPEVLQEMWPVLRNSEVNILGFALPLLIMSFCYFRIIQTLFSCKNRKKARAVRLILLVVFAFFLFWTPYNIMIFLETLKFYNFFPSCDMKRDLRLALSVTETVAFSHCCLNPFIYAFAGEKFRRYLGHLYRKCLAVLCGHPVHTGFSP-ESQRSRQDSILSS-FTHYTSEGDGSLLL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49238-1", "uniprot_id": "CX3C1_HUMAN", "id": "P49238-1", "name": "CX3C chemokine receptor 1", "aln": "-MDQFPESVTENFEY-------DDLAEACYIGDIVVFGTVFLSIFYSVIFAIGLVGNLLVVFALTNSKKPKSVTDIYLLNLALSDLLFVATLPFWTHYLINEKGLHNAMCKFTTAFFFIGFFGSIFFITVISIDRYLAIVLAANSMN-NRTVQHGVTISLGVWAAAILVAAPQFMFTKQKENE-----CLGDYPEVLQEIWPVLRNVETNFLGFLLPLLIMSYCYFRIIQTLFSCKNHKKAKAIKLILLVVIVFFLFWTPYNVMIFLETLKLYDFFPSCDMRKDLRLALSVTETVAFSHCCLNPLIYAFAGEKFRRYLYHLYGKCLAVLCGRSVHVDFSSSESQRSRHGSVLSSNFTYHTSDGDALLLL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QYD4-1", "uniprot_id": "F1QYD4_DANRE", "id": "F1QYD4-1", "name": "", "aln": "MTEEPSTVAATKTDYSDYYNEEGDFEQPCNNGQTKAFSEVFLPTLYSIVFIIGFIGNGLVVWVLVRYRHKSNMTDVCLFNLALADLLFLVSLPFWAHNAMDEWIFGRFMCHTITGLFMIGLYASIFFMVLMTLDRYAIIVHAHSVFSRNRSTKMGLALASLVWMLSLLVSLPNIIFAKDKNETNSKISCGSDFPK--DSSWMPFTYLKMNLLSLVFPLIIMIFCYSRIIPTLLSMKSQKKHKVVRLILAVVAVYFIFWTPYNIVMFLMFLQKMEYMLTCEWHNGLSLAMQWVETIALSHCCLNPIIYAFAGEKFRGAVIKVLNDQFPMCFKQ--CASFTHQLSER--RSSMFSR-----SSEISSTQIA", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : :* .* :.* *: .*. :**. :*:::* :*::** *** .*.. :: ..:**: *:****:****:.:****:* :.. : . **: *.:*:**::..***:.::::*** ** * . :. **:.: *:::: ** ::**: *:::*:* *:: * .*:*: :. * : : *:*.: :**:** :** **: **:* *.:** :.::*** ** .:*:******:::** *: ::: :* :..* *:. .**:*:*******:********** : :: . :.: : ..*: *:* :.*::* :*: .. : ", "identical_positions": 122, "similar_positions": 134, "identity": "33.06%" }, { "cls_id": "homologset.agr.MGI:1333816", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZH23-1", "uniprot_id": "D3ZH23_RAT", "id": "D3ZH23-1", "name": "", "aln": "-------------MGFLT---------AVTQGLVRGADRMSKWTSKQGPRTFT------------------------KSRGAKKTGFYTN-RKFVQIKEMVPEFVVPDLTGFKLKPYVNYRAP--AGIDTPLTAKALFLETVAPAIEKDFKEGTFDTNNLEKYG--FEPTQEGKLFQLYPKNFPR--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5BJX1-1", "uniprot_id": "RM41_RAT", "id": "Q5BJX1-1", "name": "Large ribosomal subunit protein mL41", "aln": "-------------MGFLT---------AVTQGLVRGADRMSKWTSKRGPRTFT------------------------KSRGAKKTGFYTN-RKFVQIKEMVPEFVVPDLTGFKLKPYVNYRAP--AGIDTPLTAKALFLETVAPAIEKDFKEGTFDANNLEKYG--FEPTQEGKLFQLYPKNFPR--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CQN7-1", "uniprot_id": "RM41_MOUSE", "id": "Q9CQN7-1", "name": "Large ribosomal subunit protein mL41", "aln": "-------------MGFLT---------AVTQGLVRGADRMSKWTSKRGPRTFT------------------------KSRGAKKTGIYTSDRKFVQIKEMVPEFVVPDLTGFKLKPYVNYRAP--AGIDTPLTAKALFQETVAPAIEKDFKEGTFDANNLEKYG--FEPTQEGKLFQLYPKNFPR--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IXM3-1", "uniprot_id": "RM41_HUMAN", "id": "Q8IXM3-1", "name": "Large ribosomal subunit protein mL41", "aln": "-------------MGVLA---------AAARCLVRGADRMSKWTSKRGPRSFRGR----------------------KGRGAKGIGFLTSGWRFVQIKEMVPEFVVPDLTGFKLKPYVSYLAP--ESEETPLTAAQLFSEAVAPAIEKDFKDGTFDPDNLEKYG--FEPTQEGKLFQLYPRNFLR--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q502B0-1", "uniprot_id": "RM41_DANRE", "id": "Q502B0-1", "name": "Large ribosomal subunit protein mL41", "aln": "-------------MGVLS---------ALARGFVRGADRMAEWTSKRGPRTFY------------------------KSRGARPTGIVTSSRKFIPIRAMIPEFAVPNLEGFNLKAYVSYKTP--AGTEEPMTPEKLFNEVVAPQIQRDIEEGVFSEDNLEKYG--LEKTQEGKLFKLHPKNFAR--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7JZM8-1", "uniprot_id": "RM41_DROME", "id": "Q7JZM8-1", "name": "Large ribosomal subunit protein mL41", "aln": "---------MNNCIKVVP---------IALRCQQRTISTSSVLEGKRNFRKFNAYNKRGTRVVKEAQKTLANPPVAIHKRGVRDTGILVD-GQYVEIPEKIPDIIVPDLTGCKLKPYVSYKAP--DVVQSEFTSLDLFNAVYSQKIIEDFKAGKLQKDGSAKEPSVNEQLTPEEALQRARKTGSDIF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36526-1", "uniprot_id": "RM27_YEAST", "id": "P36526-1", "name": "Large ribosomal subunit protein mL41", "aln": "MKGSPISQFSKTSINALTRPWKKYRDGELFYGLSKVGNKRVPLTTKQGNKTMY------------------------KGTRASGIGRHTKFGGYVINWKKVRTYVTPDMVNFELKPYVNANVPPLKHEFKGFSGGPLDPRLQLLKIKEYIVNGRVQSEGATDTS-------------CYKERG----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :. : . *:. :.: : . * .. :: : .*:: . :**.**. .* :: * * . : * .. :. . . ", "identical_positions": 11, "similar_positions": 35, "identity": "5.88%" }, { "cls_id": "homologset.agr.MGI:1333817", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88446-1", "uniprot_id": "S22A3_RAT", "id": "O88446-1", "name": "Solute carrier family 22 member 3", "aln": "--------------------------------------------------------------------------------------------MPTFDQALRKAGEFGRFQRRVFLLLCLTG-VTFAFLFVGVVFLGSQPDYYWCRGPRATALAER---CAWSPEEEWNLTTPELHVPAERRGQGHCHRYLLEDTN----TSSELSC-DPLAAFPNRSAPLVPCSGDWRY---VETHSTIVSQFDLVCGNAWMLDLTQAILNLGFLAGAFTLGYAADRYGRLIVYLISCFGVGITGVVVAFAPN-FSVFVIFRFLQGVFGKGAWMTCFVIVTEIVGSKQRRIVG-IVIQMFFTLGIIILPGIAYFTPSWQGIQLAISLPSFLFLLYYWVVPESPRWLITRKQGEKALQILRRVAKCNGKHLSSNYSEITVTDEEVSNPS------------CLDLVRTPQMRKCTLILMFAWFTSAVVYQGLVMRLGLIG-GNLYMDFFISGLVELPGALLILLTIERLGRRLPFAASNIVAGVSCLVTA------FLPEGIPWLRTTVATLGRLGITMAFEIVYLVNSELYPTTLRNFGVSLCSGLCDFGGIIAPFLLFRLAAIWLELPLIIFGILASVCGGLVMLLPETKGIALPETVEDVEKLGS----SQLHQCGRKKKTQVSTSNV---------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WTW5-1", "uniprot_id": "S22A3_MOUSE", "id": "Q9WTW5-1", "name": "Solute carrier family 22 member 3", "aln": "--------------------------------------------------------------------------------------------MPTFDQALRKAGEFGRFQRRVFLLLCLTG-VTFAFLFVGVVFLGSQPDYYWCRGPRATALAER---CAWSPEEEWNLTTPELHVPAERRGQGHCHRYLLEATN----TSSELSC-DPLTAFPNRSAPLVSCSGDWRY---VETHSTIVSQFDLVCSNAWMLDLTQAILNLGFLAGAFTLGYAADRYGRLIIYLISCFGVGITGVVVAFAPN-FSVFVIFRFLQGVFGKGAWMTCFVIVTEIVGSKQRRIVG-IVIQMFFTLGIIILPGIAYFTPSWQGIQLAISLPSFLFLLYYWVVPESPRWLITRKQGEKALQILRRVAKCNGKHLSSNYSEITVTDEEVSNPS------------CLDLVRTPQMRKCTLILMFAWFTSAVVYQGLVMRLGLIG-GNLYIDFFISGLVELPGALLILLTIERLGRRLPFAASNIVAGVSCLVTA------FLPEGIPWLRTTVATLGRLGITMAFEIVYLVNSELYPTTLRNFGVSLCSGLCDFGGIIAPFLLFRLAAIWLELPLIIFGILASVCGGLVMLLPETKGIALPETVEDVEKLGS----SQLHQCGRKKKTQVSTSDV---------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75751-1", "uniprot_id": "S22A3_HUMAN", "id": "O75751-1", "name": "Solute carrier family 22 member 3", "aln": "--------------------------------------------------------------------------------------------MPSFDEALQRVGEFGRFQRRVFLLLCLTG-VTFAFLFVGVVFLGTQPDHYWCRGPSAAALAER---CGWSPEEEWNRTAPASRGPEPPERRGRCQRYLLEAANDSASATSALSCADPLAAFPNRSAPLVPCRGGWRY---AQAHSTIVSEFDLVCVNAWMLDLTQAILNLGFLTGAFTLGYAADRYGRIVIYLLSCLGVGVTGVVVAFAPN-FPVFVIFRFLQGVFGKGTWMTCYVIVTEIVGSKQRRIVG-IVIQMFFTLGIIILPGIAYFIPNWQGIQLAITLPSFLFLLYYWVVPESPRWLITRKKGDKALQILRRIAKCNGKYLSSNYSEITVTDEEVSNPS------------FLDLVRTPQMRKCTLILMFAWFTSAVVYQGLVMRLGIIG-GNLYIDFFISGVVELPGALLILLTIERLGRRLPFAASNIVAGVACLVTA------FLPEGIAWLRTTVATLGRLGITMAFEIVYLVNSELYPTTLRNFGVSLCSGLCDFGGIIAPFLLFRLAAVWLELPLIIFGILASICGGLVMLLPETKGIALPETVDDVEKLGS----PHSCKCGRNKKTPVSRSHL---------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q961J5-1", "uniprot_id": "BALAT_DROME", "id": "Q961J5-1", "name": "Beta-alanine transporter", "aln": "---------------------------------------------------------------------------------------------MDFDEVLREVGSFGLYQKVIICSVLLPAALPCAFHAYSQLFIAATP-QHFCRVPELEPWTQDYVQLVKNLSIPRNRNG---AYAECSMYSRNYTDIVRYLEYRPPPDLLRQQAEDLLKLQPDTTQ-VVPCQHGWHYDK-SIYSSTVVQEWNLVCDRSFLVTLALVVFGVGGLLGNYVFGYLVDLWGRRPSFYAYLLLEIIACAASAFAWN-YYTWLGLRFVVGLTVPAILASPYVLAIELVGPERRVFCT-IVSNIAYSLGLVVLAGVIYIVRDWRELSLAVSMPLLMLFSCFFVLPESPRWLMAVGKTRRAIKILKVMARVNGVRVNRDFVERLQRKLVITRAAETKSSM-TTHYGILDLFRGPNMRRKTLIITLIWFANTSVYVGLSYYAPALG-GDEIWNFFLAGAVELPTYLLLWPGLSYFGRRWILFISMLVGGVACVATF------LYP----DITLLLYCVGKMGISSSFVVLPLMASELYPTVVRGLGMSFSSVISMVGPIVIPMINH-MGQQMLVLPLIVMGALLILGGFASLLLPETRNRNLPQTLEEGEAVPLSFLLCCCVESERKPNNIRASPKKR---ILPEAGT---------PVFHRVDTPVS---DRVPCKIVCS-----ICKNEMRTL-----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VIK2-1", "uniprot_id": "CART_DROME", "id": "Q9VIK2-1", "name": "Carcinine transporter", "aln": "------------------------------------------------------------MSDIEDNDGDEYDELSELRQRHKPESQPSVDEAFDLDDLLPTIGEFGKYQKLLVFGICLPACIPCGFCAFNQLFMADTPDDYWCRIPELLDLP---LEQRKSLSIPKELDNDELVYSKCYTYGVNWTQLLE-----------SGEEDDLTTMEPNASWPLIKCPQGWEYNT-SVVWSSIVIDFDLVCDQDIYPTIGLAALNTGGPVGVYLFGLLNDRGGRRLSYFVCLATLLAGSLMTSLSKD-FWTWAGSRVIVGLTIPAVYQIPFIISLELVGENYRSFVT-VMTCTFYTSGIMLLSGVTYLERDWVRLSYITSLPFYAYFLYMFVMPESPRWLLMRGRLEEALKILERMAKVNGREFPEAVHLKLEAQIRRDKLKKQKKKM-AN-VGLADLCRTPNMRLKTILITLSWFANETVYLGLSYYGPALG-TNQYVSFFLSAVVELPSYLCCWYFMDTWGRRWPLSLSMILGGVACVITV------MLPDDAVDETLVLYLVSKALLSASFLIIYPFAGELYPTQVRGIGIGASSYIGGLGLIGIPFITY-LGKDNLKLPLVIMGFLSMLGGMTGLRLPETLHHRLPQTIEEGEEFGKNWQFKDCCRCAQKPEILSQPASYENLDVLAGSSTNASEVELELRDSRRVREPAPRIDERTPLDTTASGSGRPVHRPSMKRLVRQMSVMDTQRTHDGTMQLTHWI", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VRR0-1", "uniprot_id": "Q9VRR0_DROME", "id": "Q9VRR0-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "MANDEKGNASTEDDDKPKKREHRDQGQQSKLKKIKYYIEPDKVDIGIQAGDSLEKVKVTYVEPDDEESSHGFFWGKKKSETSLPRRSWETDDYIDFDDLLPMIGQFGRFQIRLFLFMIPFC-FITAFVYLGQIFMCLTPPKYYCYVPELLHTPVE------LRKELSIPKEKDGSYSRCRMYNTNYTKIHFAENP---------------SAYINTSLPTIPCKKGYVFEQEGRAFESATMEFGWLCDDDKYATYAQIIFFLGSILGGLAYGHFADHCGRVAALVSSCFLALVGSLATSMSTD-FFTFAISRFLVGASYDTCFTMVYILVLEYVGPKYRTLVANLSLALFYSPFTMVMPWIALSAGNWRRFSSFTSLPIVLAMFSFCLLPESARWLVSVGEIDKALEILKNVIEVNKKQVSKEILDLFEASCTQFYK----EELDGRDFTVLSIFKRKRMARYMILMILIWMSISLVYDGHVRAASVLDSENIFLFFTIACATELPGNILVILTLDRAGRRWCSFFYTSLSGVFSLLGA--------SFQNRANMRMSALAGRFFSNICYNIGLQWAAEILPTVVRAQGVAFIHTMGFVAMLMSPPVVY-LSKKSLSSTLIVLGALGIFGGLLALFLPETLNHELPETLSDGAQFGKNQRIWHMPCCGPGSRKSHPRHNWHQGSSLRTLSKDEFRSSKMYRKTKYRFESHPSPSSSDYKGTEEKEIRTYKYGNGSKWPEDKS-------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VRT4-1", "uniprot_id": "Q9VRT4_DROME", "id": "Q9VRT4-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "---------------------MEGQAKQAYFVNEAFTYEEPPQGGGGGGADALHRRKSGGGNKELQLDMGGFKKGQ---EMAGGNGSDSLPPSMDFDDILPLIGEFGRYQKLLFICMIPFS-FFVAFVYFSQIFLTLIPEQHWCHVPELDGLDVE------ARLALSIPMTN-GEYNNCYMYDVNYTDILAQG-----------------KVMADPKWPQVKCRHGWSYNFTEIPYATVATEQNWVCDDAALPTYAQSIFFLGAIVGGLLFGWVADRFGRIPALIGTNMMGLLAGVGTAFVSN-FWEFAIMRFFVGFAFDNCFTMMYILVLEYVGPKYRTFVANMSIAIFFTGAACLLPWIAYFLADWKLLAIVTSAPLLLAIFTPFVVPESARWLVSQGKVDKAVGILKKLEKGNGRQVPPQTYQIFTDSCKRMQE----QEAQNGKYSVLDLFKSPRLRRTTLLLIVIWMAISLVFDGHVRNVGSLG-LDIFFTFTLACFTELPADTLLTVILDRFGRRWLACSSMVLSGVFSLLAT--------VVPVGIYSAALAIMGRFFVNISYNIGLQWAAEVLPTVVRAQAVAFIHIMGYVASIIAPFVVY-LANISQALPLIILGILGIIGGLLALLLPETLNHVLPQTLSDGEEFGRGQSIWDFPCLAKQVDDDEDEK--------RNADVEEVRSQAFVRGTQTGASLNAS-TGGELRSSILR--RSTKSRNSTKL------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VRQ8-1", "uniprot_id": "Q9VRQ8_DROME", "id": "Q9VRQ8-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "---------------------------------------------------------------------------------------MPPRDCEKYENFLLFIGDFGPFQKRLLFWMMPAA-FLFAFTYFGQIFMILLPKNHWCRVRELEGLPES------EQKNRGIPKKQDGSFENCFMYNVPYDSNATND--------------------ANQTRSPIPCNNGWIYDRKEVPYESIATEYNWVCDKRDFGTYSVVVYFVGCIVGCLCFGFITDHSGRLPALFLANSCSMIGGCVSVVCKD-FPCFAASRFVAGLSMNYCFVPIYILTLENVGIKYRTLVGNLALTFFFTLGACLLPWLAYVISNWRHYAMVVALPIVFMILTSLLAPESPSWLMSVGKVDRCIEVMKEAAKANGKIISEEVWSEMRECYELKFA----NEQLGKQYTSLDLFKTFPRLVVLTILIVTWMTVALAYDAHVRVVEILD-TDIFITFSLSSLVEIPAGIVPMLLLDRIGRKPMMSAVMLLCAASSLFVG--------ILKGHWNASTAAIAARFFATMAYNVGQQWASEILPTVLRGQGLAIINIMGQMGALLSPLVLS-THRYYRPLPMFIITLVSVIGALIILFLPETKGATMPQTLDEAEKR------WTLRCRDRKINEDL--------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VDV8-1", "uniprot_id": "Q9VDV8_DROME", "id": "Q9VDV8-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "---------------------------------------------------------------------------------------------MDLQSVLEKCGNFGPYQILLLGLFGYTN-IVSSLHYFSQTIISFTP-SHRCSRP--------------------EDYQPNSTSLLSCSVM--QFDKEF-------------------------------KCTSWDFER-ESNYESITTELEWVCDDAYKLAVGQSFFFIGSALGSIFFGYLADRIGRLPACVLSTLTGASGDFFTSFVGS-LPWFSFTRFISGLFMDTQYVLMYILVFEYLSPQHRTFGLNIILGVFYCVGLMISPWIAIWVTNWRNYLWAASLPALGMLLFPVFLHESAEWLLTKGKFEKAEKSLRGVAKFNGRQVDDSVFDEFIKHYREKLN--NSQNK--SSDTFMGMLRTPRLRKFTIILLIKSMIITIAFDILSRNVEGVG-ISPFKLFSYSGFCYLPAGLTIILFQNKIGRKGMACASLFVGAIITAATG-YLVATLDPSDYSVLLGFMVSLGRYGAVVAYDAEAQYAAEIIPTSVKGRGVANIHVVGNAFAFFSSYIIY-LGTFYKPLPSLMISFILLIGACLCLALPETLHKNLPQNLEEGEMFAKGEKWYFFPCFSRRPKTQKSATQLESSDGITNKL-----------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VDV7-1", "uniprot_id": "Q9VDV7_DROME", "id": "Q9VDV7-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "---------------------------------------------------------------------------------------------MDLQRVLEKCGNFGPYQILLLGLYGYTN-IVSSLHYFSQTLISFTP-SHRCSAPV-------------------EEFSQNFTELLSCSVI--QYDVDMTSF-------------------------RDNKCSSWDFDK-ESNYESITTELEWVCDDAYKLAVGQSFFFIGSALGSIFFGYLADRIGRLPACVLSTLTGASGDFFTSFVGS-LPMFSFTRFISGLSMDTQYVLMYILVFEYLSPQHRTFGLNIILGVFYSIGLMISPWIAIWLGNWRSYLWAASLPALGMLIFPLFLHESVEWLLTKGKFDKAVNNLKSVAKFNGRQVEDSVFDEFIKHYREKLN--SAQKK--SSDTFMGMLRTPRLRKFTIILLIKSMIITIAFDILSRNVEGVG-ISPFKLFSYSGFVVLPGGLSIILFQNKIGRKGMACASLLVGAFITATTG-YLVGTLDPANYSVLLGFMVCLARFGAVVAYDAEAQYAAEIIPTSVRGRGVANIHVVGNAFAFFSSYIIY-LGTFYKPLPSLLISFLLIIGACLCLTLPETLHKQLPQTLEEGEIFAKGEKWYFFPCFSRKRQSNKSESQLESANEITK-------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VDW0-1", "uniprot_id": "Q9VDW0_DROME", "id": "Q9VDW0-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "---------------------------------------------------------------------------------------------MDFSQVLDKCGNYGRFQVMILLLYGYTN-ILGSLHYFSQTLITFTP-EHWCFHADLNGLSVE------GIRSVYENISASSCTPLLGVVN--GTGVVSTN----------------------------RKCRNWIFNR-ESGYESITTELKWVCDKSHHPAVGQSFFFMGSVVGTIIFGYLSDQVGRLPSLLMATLCGATGDFITSFVHT-LPWFAFSRFMSGLSTDTMYYLMYILVFEYLSPKSRTFGLNIILAVFYCFGLMTSPWAAIWIGNWRRYLWLASLPALGVLIYPFLICESAQWLLTKRKYDDAVICLKKVAKFNRRHVEESVFDEFVKYYRERELQDYKLNS--HEDTFLAMFLTPRLRRFTLTLLVKSVIITLSCDVINRNMEGLG-TSPFKLFSFTSIVYLPAGVAILLLQNKIGRKGMACTALFVGGLITTATG-FMIAHLDPTENALLLAIMVGLGRFGATVSYDAEIQYAAEIIPTSVRGQAVSNIHVIGLASSSLAFYVIY-LAQYYKPLPSIFISCLMFFGAGLCLTLPETLNKKLPETLADGEKFALNESFLYFPCFS-RKEKNVRTESV---------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VDV6-1", "uniprot_id": "Q9VDV6_DROME", "id": "Q9VDV6-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "---------------------------------------------------------------------------------------------MDFDRVLEKCGNFGRFQFVILILYGYTN-ILSSLHYFSQTLITFTP-EHWCSHDDLMGLGAA------ELRSIYSNVSHPSCTLLSEVIN--GTGVASE-----------------------------ESCQDWIFER-ENGYESLTTELKWVCDKSHQPAVGQSFFFLGSVVGTISFGFLSDHIGRLPAMLMAALSGATGDFITSFVHT-LPWFAFSRFVSGLSTDTMYYLMYILVFEYLSPKRRTFGLNIILAVFYCFGLMTSPWIAMWIGNWRRYLWLASLPALGVLIYPLLICESAQWLLTKKKYDEAVACLKKVAKFNGRQVEDSVFDEFVKHYREKMNEESKLNK--QMDTFLGMFKTPRLRRFTTTLLVKSVIITLSYDVINRNMEGLG-SSPFKLFSLTSSVYLPAGFTILLLQNKIGRKGMACGALLVGAIITAVTG-FLIAVLDPSENAVLLALMVGLGRFGTTVSYDAEIQYAAEIIPTSVRGQAVSNIHVVGLASSSLAFYVIY-LAQYYKPLPSIFISVLMFLGALLCLTLPETLHKKLPETLADGERFAMNESCLYFPCLHKRRESLTEHEDRKSEP-----------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VFG1-1", "uniprot_id": "Q9VFG1_DROME", "id": "Q9VFG1-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "-------------------------------------------------------------------------------------------MAMDFDEILVKCGDSHRYQYMLLALYGLLM-FIVSRHYFAQNVIGFVP-DHWCYHEQLENRSYA------EIAAIYAPF-KRPSCTRLASINMDGSNATASS----------------------------EPCNRWIYHY-DHGFISMNADLNWVCDDAYKARVGQSLFFVGSMCGTLLFGLLGDRIGRIKAVVLANCCGFLGDSATIFAET-LLTFSASRFVSGLAAEANSYLMFILVLEYVSPTMRSVGLNLTMCVFYGLGMICASWQGVWLGSWRSFMVWTALPQLLVTGFYFLIQESAQWLVTRQDFDGAELRLRRVAKFNRRDVSEADYELFRQHCKTKESEARSQMSMQKQARLIDSFKLPRLRLRLIYVTVVFSIVTLCYNTMSRNVEGLS-ISPFVMFSLFALTLPPSGIFQTQVQKHFGRKFTSVVSMTATGLMTATTG-ILLAFW-TQHSATVMVCLLLMCRFGISVTTGSTMQISTELMPTCVRSSGLAVIHVTAAALSFISPFILH-LDTYFRAASSIITCILLLVSAWICLLLSETRNKKLPLTLAEGEEFGKGERMFDFMRSFKKADQHDLSADT-----IEKLMGDKRTY-----------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VFG0-1", "uniprot_id": "Q9VFG0_DROME", "id": "Q9VFG0-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "---------------------------------------------------------------------------------------------MDFDQILEKCGSAGRYQYLMILLLGYIA-FTTTVHYYSQNIIGFVP-QHWCYHEALENRSFE------EIAAIYAPFGKEASCTRLDKI--EGDRVTVSN----------------------------ETCQRWIYNY-DFGFRSMNAELNWVCNDAYKARIGQSLFFLGSLMGTFTFGVLGDRIGRVRAVILANQCGFVGDFLTTYASN-LVQFAIFRCISGLAATANYYLMFILVLEYLAPKLRNMAISGTLGICFCLGALVAPWLSVLAGNWRIYLTCSALLQLVVALFYFVVQESAQWLITRTNVEGAIARLKHIAHFNGMEVKAADFEAFRRNCIVKR---KLSNQPEQTAGIFDLLRTPNLRKVSLLVVFTFMLTSLSFNTISRNVEGMG-LSPFVVFSLFAVVVPPSGFIQGLLQSRVGRKATAFLAMLCTGLLSCALG-VALSTEGAQKNVTLLLAFALPMRLGISMCYTVTSQFASELLPTCVRSRGIAAVHLAAAGASFVSPYLIH-LGTKLAAAPSLILALLLLTASGCTLMLPETNNRQLPITLADGEAFGKGESMLSFDCWRRHDDDVSKEATEE--VRLHQLNGQTKSETEAEV------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VDV5-1", "uniprot_id": "Q9VDV5_DROME", "id": "Q9VDV5-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "---------------------------------------------------------------------------------------------MDFDQILAKCGDFNRYQFMILALFGFIN-IIVSMHYFTQTVISFVP-DHWCYHDKLVNMTYK------EIGEIYAQF-ENPSCTRLDDIN--GHNVTVSS----------------------------KACEKWIYNY-DFGYRSMNTELNWVCDSAYKARIGQSLFFIGSVVGTLFYGLLSDKIGRVPALILSNFCGFAGDFSTIFTKS-VATFTLCRFISGLAADTNFYLMYIIVLEYIRPSMRTLGLNMAVGLFYCLGLVFTPWLAVLVGHWQIYLACTSLPILLVVLYYFVVQESAQWLVTRNDIDGAIVRLKRVAKFNGCRVSQADFDEFRRHCQMTH--EMLGGDDKKQATLLDMFRTPRMRKNTLILFFKSMVITLCYDAVSRNVEGMG-ISPFIMFSLSALAVLPSSVLLVLLQDRIGRKGMASGSLLVGGLFTAAAG-IAIAYQQHNHNAILLACLTIAARFGVAISYESGSQYATELIPTCVRGQGVAAVHVAGFAASFLAPYILW-LGTFFKAAPSIILGVLFFAGSFVCLLLPETLNRSLPTTIEEGEVFGKGERMFDFPCLHNKHDDEESESELEKYKRKHSLIDAKQMQMESCSNGKRKQSLIDADHEEQALKDANH-------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VDV9-1", "uniprot_id": "Q9VDV9_DROME", "id": "Q9VDV9-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "--------------------------------------------------------------------------------------------MLEVDKILEKCGDFSRLQMIMLLLFCVIN-VLSALHYYSQTIISFVP-KYWCADG-------------------LPASIESPVDSSCLPLN---RNISTPN-----------------------------TCYSYNYEL-YMGYQSFPSEMDWVCADAWKLTLGQSMFFVGSVVGSMVLGYLADVVGRLPILIVANLIAMTGNLLTIWSTN-VTLFCMFRMISGIATDSNFVMMYILVMEYMRPSVRTLGLSICIGFFYCLGSMAAPWIAVLMRSWRGFLLTTSLPLLVVPFFYLIVPESIQWLISKQKYDSAVVCLKRVAKINGRHVEESAYAEFIEECKCSQ-----QNQ-KASPHLLDLFQTPRLRRHTLILFFKSMVITLCYDAVSRNVQGLG-ISPFVMFSLSATAILPACLLIIALQDRIGRKAMASASLLLSGIFISVTGGIIFAASASDKTTTLLVSLSVVGRFGVTVAYNSGAQYATELIPTCVRGQGVAAVHVAGYAFTFFSAYILF-TRSVFSPLPEIILGVLSLLGACLCLLLPETLHRTLPTSLEDGENFGKNDRWYTFSFLEGRTQSAATLDTQNAKMYSQSTESAVYF------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VD40-1", "uniprot_id": "Q9VD40_DROME", "id": "Q9VD40-1", "name": "Carcinine transporter", "aln": "--------------------------------------------------------------MRDKKEQANSRKASQVSGHFSQMDVDDSEFNDPFQALMEKAGNHGRYQTLYNFVFVGGLAFSGAMIYMNIILALNIP-DHWCTVPGRENTNFSLEEWRDITLPKQADNRGRKTFSNCEMFQMNFSEITDWSAWN-----------------SNLTKTTEACQNGWSYDK-TWYESTIPTDHNWVCAKDLFVTNVFVVGRVTEVAGSFILGQMGDSYGRRFVYYISVVFCSLGRLGSIMCTSSYTWFLIMSGIVGLTVNSLFQSPQIIGMEISREEDR-SRIAFFQSCGWSIGTTLMPLLYWWLRHWDSFMWLTSIPTAMVLLFSKYVIESPRWLISKQRFREAIVQLQKIAKINGHRFDMTEKELAEIYSRDKQD---------VTYGIASLFAGWRLARNTTIMGFSWCVVAVSYFTLVLFSSRMA-GNPFLNFLYQSIVEIPAYVVGRYMGDTYGRRFTNSVSFLISFVTCLPII----VYSTDERYENLMIYLATFIKFLNALTFFTVNLQCLEIYPTCMRQTGVALGTILANAIGVLAPYLVYLGTTVDIRAPYYILGVLFLLGGIGALFLPETLHKKLPDTMEEAGHFGKHDKFFSLPKPPQAAEKDDKLSSHPELTRLRRSETAP--------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : *. * . . * : * : : : : :* * * * ** : . * :: * * : . * : ** **: . :. . * . : . : . * * . **: : *: ** :: .:. : . . : . : *.** :* .: : ", "identical_positions": 30, "similar_positions": 48, "identity": "3.94%" }, { "cls_id": "homologset.agr.MGI:1333818", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62081-1", "uniprot_id": "RS7_HUMAN", "id": "P62081-1", "name": "Small ribosomal subunit protein eS7", "aln": "MFSSSAKIVKPNGEKPDEFESGISQALLELEMNS-DLKAQLRELNITAAKEIEVGGGRKAIIIFVPVPQLKSFQKIQVRLVRELEKKFSGKHVVFIAQRRILPKPTRKSRTKNKQKRPRSRTLTAVHDAILEDLVFPSEIVGKRIRVKLDGSRLIKVHLDKAQQNNVEHKVETFSGVYKKLTGKDVNFEFPEFQL--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62082-1", "uniprot_id": "RS7_MOUSE", "id": "P62082-1", "name": "Small ribosomal subunit protein eS7", "aln": "MFSSSAKIVKPNGEKPDEFESGISQALLELEMNS-DLKAQLRELNITAAKEIEVGGGRKAIIIFVPVPQLKSFQKIQVRLVRELEKKFSGKHVVFIAQRRILPKPTRKSRTKNKQKRPRSRTLTAVHDAILEDLVFPSEIVGKRIRVKLDGSRLIKVHLDKAQQNNVEHKVETFSGVYKKLTGKDVNFEFPEFQL--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62083-1", "uniprot_id": "RS7_RAT", "id": "P62083-1", "name": "Small ribosomal subunit protein eS7", "aln": "MFSSSAKIVKPNGEKPDEFESGISQALLELEMNS-DLKAQLRELNITAAKEIEVGGGRKAIIIFVPVPQLKSFQKIQVRLVRELEKKFSGKHVVFIAQRRILPKPTRKSRTKNKQKRPRSRTLTAVHDAILEDLVFPSEIVGKRIRVKLDGSRLIKVHLDKAQQNNVEHKVETFSGVYKKLTGKDVNFEFPEFQL--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P62084-1", "uniprot_id": "RS7_DANRE", "id": "P62084-1", "name": "Small ribosomal subunit protein eS7", "aln": "MFSTSAKIVKPNGEKPDEFESGISQALLELEMNS-DLKAQLRELHITAAKEIEVGGSRKAIIIFVPVPQLKSFQKIQVRLVRELEKKFSGKHVVFIAQRRILPKPTRKSRTKNKQKRPRSRTLTNVHDAILEDLVFPSEIVGKRIRVKLDSSRLIKVHLDKAQQNNVEHKVETFAGVYKKLTGKDVIFEFPEFQL--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VA91-1", "uniprot_id": "RS7_DROME", "id": "Q9VA91-1", "name": "Small ribosomal subunit protein eS7", "aln": "-MAIGSKIIKPGGSDPDDFEKSIAQALVELEANS-DLKPYLRDLHITRAREIEFG-SKKAVIIYVPIPQQKVFQKIQIILVRELEKKFSGKHVVVIAERKILPKPTRKARNPLKQKRPRSRTLTAVYDAILEDLVFPAEIVGKRIRVKLDGSQLVKVHLDKNQQTTIEHKVDTFTSVYKKLTGRDVTFEFPDNYLNV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P48164-1", "uniprot_id": "RS7B_YEAST", "id": "P48164-1", "name": "Small ribosomal subunit protein eS7B", "aln": "MSSVQSKILS---QAPSELELQVAKTFIDLESSSPELKADLRPLQIKSIREIDVTGGKKALVLFVPVPALSAYHKVQTKLTRELEKKFPDRHVIFLAERRILPKPSRTSR--QVQKRPRSRTLTAVHDKVLEDMVFPTEIVGKRVRYLVGGNKIQKVLLDSKDVQQIDYKLESFQAVYNKLTGKQIVFEIPSQTN--", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P26786-1", "uniprot_id": "RS7A_YEAST", "id": "P26786-1", "name": "Small ribosomal subunit protein eS7A", "aln": "MSAPQAKILS---QAPTELELQVAQAFVELENSSPELKAELRPLQFKSIREIDVAGGKKALAIFVPVPSLAGFHKVQTKLTRELEKKFQDRHVIFLAERRILPKPSRTSR--QVQKRPRSRTLTAVHDKILEDLVFPTEIVGKRVRYLVGGNKIQKVLLDSKDVQQIDYKLESFQAVYNKLTGKQIVFEIPSETH--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :**:. . * ::* :::::::** .* :**. ** *::. :**:. .:**: ::**:* ::*:* *.******* .:**:.:*:*:*****:*.:* ********** *:* :***:***:******:* :...:: ** **. : :::*:::* .**:****::: **:*. ", "identical_positions": 80, "similar_positions": 69, "identity": "40.61%" }, { "cls_id": "homologset.agr.MGI:1333819", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99JD2-1", "uniprot_id": "TEKT1_RAT", "id": "Q99JD2-1", "name": "Tektin-1", "aln": "MAKLLQSPPKFLPAEWYIANKSQYHRAEAQRSRSERLVAESQRLVEEIEKTTRKSQSDVNKKLEQRLEEVKFWKKELDDKLEHLVNETEDLLTYKIRLERSLESYKEPLHITEKCLAYREKRVGIDLVHDVVDQELQKEADIIHGVMNLLTRTVEEATEQIRLNRSAKYNLEKDLKDKFTAITIDDICFSLNNNSPDIKYSENVVRIEPNSVSLEDWLDFSNTNMQKADKQLNNSMALKTLVDQILSQTANDLRRQCEVVDTAFVNGLKETKDARNKLADHLAKVMDEIASQEKNIEVLENAITQQEGPAKVAHTRLENRTYRPNVELCRDVAQYRLIREVQEIKHNVARLEETLAQAQIQLKALFRRQLALQEEIQVKENTIYIDQVLCMEMRKSIPPRDGDDHGAWEGGIRAEAIC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DAJ2-1", "uniprot_id": "TEKT1_MOUSE", "id": "Q9DAJ2-1", "name": "Tektin-1", "aln": "MAKLLQSPPRFLPEEWYIANKSQYHRAEAQRSQSERLVAESQRLVEEIEKTTRKSQSDVNKKLEQRLEEVRFWKKELDDKLEQLVNQTDDLLTYKTRLERSLESYKEPLHITEKCLEYREKRVGIDLVHDVVEQELQKEADIIHGVMNLLIRTLEESTEQIRLNRSAKYNLEKDLRDKFTAITIDDVCFSLNNNSPNINFSEKVVRIEPNSVSLEDWLDFSNANVEKADKQLNNSTALKTLVDQILSQTANDLRRQCEVVDEAFINGLKETKDARNKLADHLAKVMEEIASQEKNIMALENAITQQEGPAKVAHTRLETRTHRPNVELCRDIAQYRLIKEIQEINHNVARLKETLAQAQTQLKALYRRQLALQEEIQVKENTIYIDQVLCMEMRKSIPPRDGDDHGAWEGGIRAEAIC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q969V4-1", "uniprot_id": "TEKT1_HUMAN", "id": "Q969V4-1", "name": "Tektin-1", "aln": "MAKLLQPPPKFLPSEWHIANKNQYHRADAQRSRSERLVAESQRLVDEIEKTTRKSQSDVNKKLEQRLEEVQFWKKELDDKLEQLVNVTDDLLIYKIRLEKALETLKEPLHITETCLAYREKRIGIDLVHDTVEHELIKEAEIIQGIMALLTRTLEEASEQIRMNRSAKYNLEKDLKDKFVALTIDDICFSLNNNSPNIRYSENAVRIEPNSVSLEDWLDFSSTNVEKADKQRNNSLMLKALVDRILSQTANDLRKQCDVVDTAFKNGLKDTKDARDKLADHLAKVMEEIASQEKNITALEKAILDQEGPAKVAHTRLETRTHRPNVELCRDVAQYRLMKEVQEITHNVARLKETLAQAQAELKGLHRRQLALQEEIQVKENTIYIDEVLCMQMRKSIPLRDGEDHGVWAGGLRPDAVC", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******.**:*** **:****.*****:****:************:************************:***********:*** *:*** ** ***::**: ********.** *****:*******.*::** ***:**:*:* ** **:**::****:************:***.*:****:*********:*.:**:.*****************.:*::***** *** **:***:**********:**:*** ** ****:*****:**********:********* .**:** :*************.**:*********:*****::*:***.******:******* :**.*.********************:****:****** ***:***.* **:*.:*:*", "identical_positions": 332, "similar_positions": 67, "identity": "79.43%" }, { "cls_id": "homologset.agr.MGI:1333820", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P0C2C1-1", "uniprot_id": "RM30_RAT", "id": "P0C2C1-1", "name": "Large ribosomal subunit protein uL30m", "aln": "-MAGVLRSVFQRPPGRLQTVKKGAESLIGTEWIRHKFTRSRIPDKVFQPRPEDHEKYGGDPQNPHKLHIVTRIRSTKRRPYWEKDTIKMLGLQKAHS-PQIHKNIPSVNAKLKVVKHLIRIQPLKLPQGLPTEETMSSTCLKSTGELVVQWHLKPVEQEAKS----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D7N6-1", "uniprot_id": "RM30_MOUSE", "id": "Q9D7N6-1", "name": "Large ribosomal subunit protein uL30m", "aln": "-MAGVLRSAFPRPPCRLQTVKKGAESLIGTEWIRHKFTKSRIPDKVFQPKPEDHEKYGGDPQNPHKLHIVTRIRSTKRRPYWEKDTIKMLGLQKAHS-PQIHKNIPSVNAKLKVVKHLIRIQPLKLPQGLPTEETMSSTCLKSTGELVVQWHLKPVEQEAKS----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TCC3-1", "uniprot_id": "RM30_HUMAN", "id": "Q8TCC3-1", "name": "Large ribosomal subunit protein uL30m", "aln": "-MAGILRLVVQWPPGRLQTVTKGVESLICTDWIRHKFTRSRIPEKVFQASPEDHEKYGGDPQNPHKLHIVTRIKSTRRRPYWEKDIIKMLGLEKAHT-PQVHKNIPSVNAKLKVVKHLIRIKPLKLPQGLPAEENMSNTCLKSTGELVVQWHLKPVEQKAHES---------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I5ZM40-1", "uniprot_id": "A0A8I5ZM40_RAT", "id": "A0A8I5ZM40-1", "name": "", "aln": "-MAGVLHSIFLRPPGRLQSVKKGSESLIRTEWIYHKFIRSRLPDKVFEPRPEGHEKHNGDPHNPHKLHIVTRI-SIKRCLFWEKHTIKELRLQKAHS-LQSHKDIQQVNAKPEVVKHLMRIQPLKLPQGLPTEETMSSMCLKSTGELVVQSHLNPVEQEAKS----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9W4I3-1", "uniprot_id": "Q9W4I3_DROME", "id": "Q9W4I3-1", "name": "Large ribosomal subunit protein uL30m", "aln": "MNLGRLLNPLRSTACSVRSYGKHNKKFLYKNGQ-------KFEGITYYPRTPDHQDP---PVEPAKLFRVQRIKPLKGNPYWENRILKDLGLDGKQSDFTVVKNIPENNARLWKIKHLIKVTPVTFPYGEPTAQDVRHTILKENGECLVTKDLGPIDTRLAARQDYDEQPKRLDTDLLRKDARLKWLNPW", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * . .. ::: * :.:: .: :: .: . . .*:. * :* **. * ** . : :**: :* * *: :: *:* . **: :***::: *:.:* * *: : : **..** :* .* *:: . ", "identical_positions": 34, "similar_positions": 51, "identity": "17.89%" }, { "cls_id": "homologset.agr.MGI:1333821", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VF18-1", "uniprot_id": "Q8VF18_MOUSE", "id": "Q8VF18-1", "name": "Olfactory receptor", "aln": "--MEENQTTVTEFILLGFCLGPRIHLVLFLLFSLFYTLTILGNGTILAMICLDSRLHTPMYFFLSHLAIVDMAYACNTVPQTLINLLDETRPITFAGCMTQTYLFLTFAITECLLLVVMSYDRYVAICHPLHYTVIMNWRVCTIMAAVSWIVSFLLSLVHLLLILRLPFCGPHEINHFFCEILSVLKLACADTTLNQVVIFAACVFTLVGPLCFVLVSYTRILVAILRIQSGERRRKAFSTCSSHLCVVGLFFGSAIVMYMAPKS--QHPEEQQKILFLFYSFFNPMLNPLIYSLRNAEVKGALRRALCKESHSCLVWCSHHKPW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZFA4-1", "uniprot_id": "D3ZFA4_RAT", "id": "D3ZFA4-1", "name": "Olfactory receptor", "aln": "--MKENQTVVTEFILLGFCLGPRIHLVLFLLFSLFYMFTILGNGTILAMICLDSRLHTPMYFFLSHLAIVDMAYACNTVPQTLVNLLDETKPISFTGCMTQTYLFLTFAITECLLLVVMSYDRYVAICHPLHYSVIMNWRACSILAAVSWIVSFLLSLVHLLLILRLPFCGPHEINHFFCEILSVLKLACADTTLNQLVIFTACVFTLVGPLCFVLVSYMRILVAILRIQSGEGRRKAFSTCSSHLCVVGLFFGSAIVMYMAPKS--EHPEEQQKILFLFYSFFNPMLNPLIYSLRNAEVKGALWRVLCKESHSCLVWCSHHKA-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NGT9-1", "uniprot_id": "OR2A1_HUMAN", "id": "Q8NGT9-1", "name": "Olfactory receptor 2A1/2A42", "aln": "--MGENQTMVTEFLLLGFLLGPRIQMLLFGLFSLFYIFTLLGNGAILGLISLDSRLHTPMYFFLSHLAVVDIAYTRNTVPQMLANLLHPAKPISFAGCMTQTFLCLSFGHSECLLLVLMSYDRYVAICHPLRYSVIMTWRVCITLAVTSWTCGSLLALAHVVLILRLPFSGPHEINHFFCEILSVLRLACADTWLNQVVIFAACVFFLVGPPSLVLVSYSHILAAILRIQSGEGRRKAFSTCSSHLCVVGLFFGSAIIMYMAPKS--RHPEEQQKVFFLFYSFFNPTLNPLIYSLRNGEVKGALRRALGKESHS-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q2PRL2-1", "uniprot_id": "Q2PRL2_DANRE", "id": "Q2PRL2-1", "name": "", "aln": "MANETYMKNVDSFIITGFDH-LQNQKLLGSLILISYMFILIGNIINLCIISTDRHLHKPMYILICNLAVVDIMYSSTCSTTMISVLLAEIKMVSYYSCITRTFFYHVADIAECMALTLMAIDRVVAIRLPLRYHSIVTNLRTFCFIFVTWLMGFAAVGFFTSVLDKSPYCQP-LIKYAFCSYSSLVRAACVDPEPYFVISTIYSMVPLCGLFPFVMCTYAFLAYSVTKLSNSS-RKQMINTCLSHLIVLLSYYAPKVVTILLTRIGVVLTVTDRNAILIAASLVPPLINPTVYCTRTKEIRRRLSDFFLSTKILPNNFK------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * .*:: ** : : :* *: : * : ::** * :*. * :**.***:::.:**:**: *: . . : ** : ::: .*:*:*:: :**: *.:*: ** *** **:* *:. : .:* . . :: : *:. * *:: **. *::: **.*. :: .:. * * :*: :* : :: ::.... *:: :.** *** *: ::.. :: : .: . ::: ::: *:. * :** :*. *. *:: * : . . ", "identical_positions": 69, "similar_positions": 111, "identity": "21.23%" }, { "cls_id": "homologset.agr.MGI:1333822", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P17105-1", "uniprot_id": "IP3KA_RAT", "id": "P17105-1", "name": "Inositol-trisphosphate 3-kinase A", "aln": "MTLPGHPTGMARPRGAGPCSPGLERAPRRSVGELRLLFEARCAAVAAAAAAGEPRARGAKRRGGQVPNGLPRAAPAPVIPQLTVTSEE-DVAPASPGPPDREGNWLPAAG-SHLQQPRRLSTSSLSSTGSSSLLEDSEDDLLSDSESRSRGNVQLETSEDVGQKSHWQKIRTMVNLPVMSPFKKRYSWVQLAGHTGSFKAAGTSGLILKRSS--EPEHYCLVRLMADVLR--GCVPAFHGVVERDGESYLQLQDLLDGFDGPCVLDCKMGVRTYLEEELTKARERPKLRKDMYKKMLAVDPEAPTEEEHAQRAVTKPRYMQWREGISSSTTLGFRIEGIKKADGSCSTDFKTTRSREQVTRVFEEFMQGDAEVLKRYLNRLQQIRDTLEISDFFRRHEVIGSSLLFVHDHCHRAGVWLIDFGKTTPLPDGQILDHRRPWEEGNREDGYLLGLDNLIGILANLAER----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R071-1", "uniprot_id": "IP3KA_MOUSE", "id": "Q8R071-1", "name": "Inositol-trisphosphate 3-kinase A", "aln": "MTLPGRPTGMARPRGAGPCSPGLERAPRRSVGELRLLFEARCAAVAAAAAAGEPRARGAKRRGGQVPNGLPRAAPAPVIPQLTVTSEE-DVTPASPGPPDQEGNWLPAAG-SHLQQPRRLSTSSLSSTGSSSLLEDSEDDLLSDSESRSRGNVQLETSEDVGQKSHWQKIRTMVNLPVMSPFRKRYSWVQLAGHTGSFKAAGTSGLILKRSS--EPEHYCLVRLMADVLR--GCVPAFHGIVERDGESYLQLQDLLDGFDGPCVLDCKMGVRTYLEEELTKARERPKLRKDMYKKMLAVDPEAPTEEEHAQRAVTKPRYMQWREGISSSTTLGFRIEGIKKADGSCSTDFKTTRSREQVTRVFEEFMQGDAEVLRRYLNRLQQIRDTLEISDFFRRHEVIGSSLLFVHDHCHRAGVWLIDFGKTTPLPDGQILDHRRPWEEGNREDGYLLGLDNLIGILASLAER----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P23677-1", "uniprot_id": "IP3KA_HUMAN", "id": "P23677-1", "name": "Inositol-trisphosphate 3-kinase A", "aln": "MTLPGGPTGMARPGGARPCSPGLERAPRRSVGELRLLFEARCAAVAAAAAAGEPRARGAKRRGGQVPNGLPRAPPAPVIPQLTVTAEEPDVPPTSPGPPERERDCLPAAGSSHLQQPRRLSTSSVSSTGSSSLLEDSEDDLLSDSESRSRGNVQLEAGEDVGQKNHWQKIRTMVNLPVISPFKKRYAWVQLAGHTGSFKAAGTSGLILKRCS--EPERYCLARLMADALR--GCVPAFHGVVERDGESYLQLQDLLDGFDGPCVLDCKMGVRTYLEEELTKARERPKLRKDMYKKMLAVDPEAPTEEEHAQRAVTKPRYMQWREGISSSTTLGFRIEGIKKADGSCSTDFKTTRSREQVLRVFEEFVQGDEEVLRRYLNRLQQIRDTLEVSEFFRRHEVIGSSLLFVHDHCHRAGVWLIDFGKTTPLPDGQILDHRRPWEEGNREDGYLLGLDNLIGILASLAER----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VL83-1", "uniprot_id": "Q9VL83_DROME", "id": "Q9VL83-1", "name": "Kinase", "aln": "--MTMTSTVLQRPIQAKPEKKASSKSTSSSRSRSTMAWSNEKLRFSCIDNIGLKQLWKLIALDTSASSKQRSAMMLEVEQQQQQQQQQ---------QSNNNNERIPNENCDYLSLQR-------SGQAPKNHIQAQDPAQMSLLKFLAINALELSAPATPHLLQHQQAHKQAK----------PQGWMQLSGHPESIVPT-STGIVRKRISGLEDSEVHAYRLICKEPQTAQIVPAYFGIQEMQSQHFIELQDLLAGFRDPCVMDIKMGSRTFLESEVSNATLRP----DLYQKMIAVDAGAPTPAEHEARAITKLRYMTFRESLSSSHSKGFRIEALRLRGRPPVKDLKTCRSSEQIAQTIEQFLAARRSVQKELLKRLKHMRLVIEQSTFFASHEIIGSSIFIVYDD-DRVGVWLIDFAKCRELPPHVRVDHRSAWAPGNREEGLLRGMDELIRSFEEVYARCGSHRSCLKI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. .* : ** * * . . .::. * .. : :. . .:. * : . .... * * * :: .:.: : :* . .:*. * *. .... :: .: :* : : . ::*.: .* * : .*:**:**. *: .: ::*:: ** * * .. **:.. : ***:.*: * :.: :::***** ** .***:* *** **:**.*:::* ** *:*:**:***. *** ** **:** *** :**.:*** : *****.:: . . .*:** ** **: :.:*:*: . .* :. *:**:::* .:* * ** **:****:::*:*. .*.*******.* ** :*** .* ****:* * *:*:** : .: * ", "identical_positions": 139, "similar_positions": 138, "identity": "29.26%" }, { "cls_id": "homologset.agr.MGI:1333824", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A959-1", "uniprot_id": "A0A8I6A959_RAT", "id": "A0A8I6A959-1", "name": "Olfactory receptor", "aln": "--------MVSQNQTVVAEFVLQGFSEHPSLRLFLTGCFLSLYAMALMGNIVIIALVTSSTGLHSPMYFFLCNLSTMDIICTSSVLPKALVGLLSEENIISFKGCMTQLFFLVWSGSSELLLLTVMAYDRYVAICAPLHYSTRMSPQLCGILAIGVWSVCALNASINTGLMTRLSFCGPKVITHFFCEIPPLLLLSCSSTYVNSIMTLVADAFYGGINFVLTLLSYGCIIASILHMRSAEGKRKAFSTCSSHLIVVTMYYSSVFCAYISPGSSYNPERSKFTSVLYSVLSPTLNPLIYTLRNKDVKLALGRILASFSH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0LKH3-1", "uniprot_id": "A0ABK0LKH3_RAT", "id": "A0ABK0LKH3-1", "name": "Olfactory receptor", "aln": "------TKMVSPNQTVVTEFVLQGFSEHPSLSLFLTGCFLSLYAMALMGNIVIIALVTSSTGLHSPMYFFLCNLATMDIICTSSVLPKALVGLLSEENTISFKGCMTQLFYLLWSGSSEMLLLTVMAYDRYVAICCSLHYSSRMSPQLCGVVAIGVWSVCALNASINTGLMTRLSFCGPKVITHFFCEIPPLLLLSCSPTNVNSIMTLVADIFYAGINFGLTLLSYGCIIASILHMRSAEGKREAFSTCSSHLIVVAMYYSSVFFAYINPRSSYNPERSKFTTVLYSVLSPTLNPLIYTLRNKDVKLALGRIFASFSH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6ABX6-1", "uniprot_id": "A0A8I6ABX6_RAT", "id": "A0A8I6ABX6-1", "name": "Olfactory receptor", "aln": "--------MVSPNQSVVTEFVLQGFSEHPSLKLFLTGCFLSLYTMALMGNIVIIALVTSSTGLHSPMYFFLCNLATMDIICTSSVLPKALVGLLSEENTISFKGCMTQLFFLVWSGSSELLLLTVMAYDRYVAICCPLHYSSRMSPQLCGVVVIGVWSVCALNASINTGLMTRLSFCGPKVITHFFCEIPPLLLLSCSPTYVNSIMTLASDAFYGGINFVLTLLSYGCIIASILRMRSAEGKKKAFSTCSSHLIVVVMYYSSVFCAYISPASSYSPERNKFTSVLYSILSPTLNPLIYTLRNKDVKHALGRIFASFSH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VGJ4-1", "uniprot_id": "Q8VGJ4_MOUSE", "id": "Q8VGJ4-1", "name": "Olfactory receptor", "aln": "MNWILHSTMVSPNQTVVTEFVLQGFSEHPSLRLFLMGCFLSLYTVALMGNMVIIALITSSTGLHSPMYFFLCNLATMDIICTSSVLPKALVGLLSEENTISFKGCMTQLFFLVWSGSSELLLLTVMAYDRYVAICLPLHYSSRMSPQLCGTFAVGVWSICALNASINTGLMTRLSFCGPKVITHFFCEIPPLLLLSCSPTYINSVMTLVADAFYGGINFLLTLLSYGCIIASILRMRSAEGKRKAFSTCSSHLIVVSVYYSSVFCAYISPGSSYSPERSKFTSVLYSVLSPTLNPLIYTLRNKDVKLALRRLFPSFSN", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *** **:**:************* *** *******::*****:*****:*****************:*********************** ***********:*:******:*************** .****:******** ..:****:***************************************.* :**:***.:* **.**** **************:*******::************ :****** ***.* ***.***.***:****:****************** ** *::.***:", "identical_positions": 261, "similar_positions": 35, "identity": "82.08%" }, { "cls_id": "homologset.agr.MGI:1333825", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ERM3-1", "uniprot_id": "DGAT1_RAT", "id": "Q9ERM3-1", "name": "Diacylglycerol O-acyltransferase 1", "aln": "MGDRGGAGSSRRRRTGSRVSVQGGSGPKVEEDEVREAAVSPDLGAGGDAPAPAPAPAHTRDKDRQTSVGDGHWELRCHRLQDSLFSSDSGFSNYRGILNWCVVMLILSNARLSLENLIKYGILVDPIQVVSLFLKDPYSWPAPCLIIASNIFIVATFQIEKRLSVGALTEQMGLLLHVVNLATIICFPAAVALLVESITPVGSLFALASYSIIFLKLSSYRDVNLWCRQRRVKAKAVSAGKKVSGAAAQNT-------VSYPDNLTYRDLYYFIFAPTLCYELNFPRSPRIRKRFLLRRVLEMLFFTQLQVGLIQQWMVPTIQNSMKPFKDMDYSRIIERLLKLAVPNHLIWLIFFYWLFHSCLNAVAELLQFGDREFYRDWWNAESVTYFWQNWNIPVHKWCIRHFYKPMLRLGSNKWMARTGVFWASAFFHEYLVS----IPLRMFRLWAFT--AMMAQVP--LAWIVNRF-FQGNYGNAAVWVTLIIGQPVAVLMYVHDYYVLNYDAPVGA-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z2A7-1", "uniprot_id": "DGAT1_MOUSE", "id": "Q9Z2A7-1", "name": "Diacylglycerol O-acyltransferase 1", "aln": "MGDRGGAGSSRRRRTGSRVSVQGGSGPKVEEDEVRDAAVSPDLGAGGDAPAPAPAPAHTRDKDGRTSVGDGYWDLRCHRLQDSLFSSDSGFSNYRGILNWCVVMLILSNARLFLENLIKYGILVDPIQVVSLFLKDPYSWPAPCVIIASNIFVVAAFQIEKRLAVGALTEQMGLLLHVVNLATIICFPAAVALLVESITPVGSVFALASYSIMFLKLYSYRDVNLWCRQRRVKAKAVSTGKKVSGAAAQQA-------VSYPDNLTYRDLYYFIFAPTLCYELNFPRSPRIRKRFLLRRVLEMLFFTQLQVGLIQQWMVPTIQNSMKPFKDMDYSRIIERLLKLAVPNHLIWLIFFYWFFHSCLNAVAELLQFGDREFYRDWWNAESVTYFWQNWNIPVHKWCIRHFYKPMLRHGSSKWVARTGVFLTSAFFHEYLVS----VPLRMFRLWAFT--AMMAQVP--LAWIVGRF-FQGNYGNAAVWVTLIIGQPVAVLMYVHDYYVLNYDAPVGV-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75907-1", "uniprot_id": "DGAT1_HUMAN", "id": "O75907-1", "name": "Diacylglycerol O-acyltransferase 1", "aln": "MGDR---GSSRRRRTGSRPSSHGGGGPAAAEEEVRDAAAGPDVGAAGDAPAPAPN------KDGDAGVGSGHWELRCHRLQDSLFSSDSGFSNYRGILNWCVVMLILSNARLFLENLIKYGILVDPIQVVSLFLKDPYSWPAPCLVIAANVFAVAAFQVEKRLAVGALTEQAGLLLHVANLATILCFPAAVVLLVESITPVGSLLALMAHTILFLKLFSYRDVNSWCR--RARAKAASAGKKASSAAAPHT-------VSYPDNLTYRDLYYFLFAPTLCYELNFPRSPRIRKRFLLRRILEMLFFTQLQVGLIQQWMVPTIQNSMKPFKDMDYSRIIERLLKLAVPNHLIWLIFFYWLFHSCLNAVAELMQFGDREFYRDWWNSESVTYFWQNWNIPVHKWCIRHFYKPMLRRGSSKWMARTGVFLASAFFHEYLVS----VPLRMFRLWAFT--GMMAQIP--LAWFVGRF-FQGNYGNAAVWLSLIIGQPIAVLMYVHDYYVLNYEAPAAEA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58HG58-1", "uniprot_id": "A0AC58HG58_DANRE", "id": "A0AC58HG58-1", "name": "", "aln": "MIDKDDFGPVTRNRRRATITSTRSESVKLRNG-ASAAAAAADSGLKSGHKARESLAKNLQLNEENKRKCDRYDRMSCHKLQESMLSSASSFKNYRGILNWCVVMLVLSNARLFLENLLRYGILVDPIQVVSLFLKDPYSWPAACLVIVCNAFILVALYTERKLAMGSISEKVGLLIYIFNLTIILCFPMVVVLKLPSITPVGGAFALGIYTILFLKLYSYKDVNKWCR-ERTQAKARSLSRSLSCPSPPSTSSSMQSYVSYPGNLSLRDIYYFVFAPTLCYELNFPRSESIRMGFLLRRLFEMLLLTQLLVGLTQQWMVPIIRSSMKPLQEMDYTRMTERLLRLAVPNHLLWLIFFYSFFHSSMNFMAELLRFGDREFYRDWWNSETITYFWQNWNIPVHKWCLRHFYKPLLRRGAGKLLSQSAVFFASAFFHEDRMSSAVCADWKGFLILKVSSSSVSGQCSSQDVQTVGIYGHDGTDSTGMVSVQVSSRQLWKCCCVALTHYRSTYRRSHVCS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* *: *. *.* : : . . : . **...* * .. * . :: . : : **:**:*::** *.*.*************:****** ****::***********************.*::*..* * :.:: *::*::*:::*: ***::: **: *:*** .*.* : ******. :** ::*:**** **:*** *** *.:*** * .:. * .:. : ****.**: **:***:************** ** *****::***::*** *** ****** *:.****:::***:*: ****:*******:****** :***.:* :***::************:*::***************:******:** *:.* ::::.** :****** :* : * : .: .: .* . . *. : .:*. ... * : : * . :* .* . ", "identical_positions": 246, "similar_positions": 129, "identity": "47.77%" }, { "cls_id": "homologset.agr.MGI:1333827", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZW04-1", "uniprot_id": "D3ZW04_RAT", "id": "D3ZW04-1", "name": "", "aln": "MDDAHNIQYSNLQDNAQAE---QELDNAQATMAAAEEEEATSTSKAEYGSGIPS----------------------------PLQSPERACSPSVALASIPVGPSEEASIRQLEA-------LEDPLYLLHNAQNVKVYDLVDFLLFKYQTKAFTTKA-----EMLETIGREYDEYYPLIFSEASECMKLVFGLDIVEVDPSVHSYV---LVTALGITYDGMLTDVQGMPKTGVLIVVLGVIFMKGNYVSEDIIWEMLNNIGLCGGMDP-YIHRDPRKLISEEFVQEGYLEYR--QVPNSDPPSHVFLWGPRAFAETTKLKVLQFFASITKTHPRAYPEKYAEALRDEIDRVEAWIFQ---------QMLRHL-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O89012-1", "uniprot_id": "O89012_MOUSE", "id": "O89012-1", "name": "", "aln": "MADSHNIQYCNLQESAQAQ---QELDNDQETMVTSQEEEVTTTSNKVYGSGIPS----------------------------PPQSPQRAYSPCVALASIPDSPSEEASIKGSEG-------LEDPLYLLHNAQNTKVYDLVDFLVLNYEMKAFPTKA-----EMLESIGREYEEYYPLIFSEASECLKMVFGLDMVEVDPFVHSYM---LVTALGITYDGMMTDVQGMPKTGILIAVLSVIFMKGNYVSEEIIWEMLNNIGLCGGRNP-YIHKDPRKLISEEFVQEGYLEYR--QVPNSDPPSYGFLWGPRAFAETSKMKVLQFFASINKTHPRAYPEKYAEALQDEIDRTKAWILN---------RCSNFSDLLTF--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P43363-1", "uniprot_id": "MAGAA_HUMAN", "id": "P43363-1", "name": "Melanoma-associated antigen 10", "aln": "MPRAPKRQRCMPEEDLQSQSETQGLEGAQAPLAVEEDASSSTSTSSSFPSSFPSSSSSSSSSCYPLIPSTPEEVSADDETPNPPQSAQIACSSPSVVASLPLDQSDEGSSSQKEESPSTLQVLPDSESLPRSEIDEKVTDLVQFLLFKYQMKEPITKA-----EILESVIRNYEDHFPLLFSEASECMLLVFGIDVKEVDPTGHSFV---LVTSLGLTYDGMLSDVQSMPKTGILILILSIVFIEGYCTPEEVIWEALNMMGLYDGMEH-LIYGEPRKLLTQDWVQENYLEYR--QVPGSDPARYEFLWGPRAHAEIRKMSLLKFLAKVNGSDPRSFPLWYEEALKDEEERAQDRIATTDDTTAMASASSSATGSFSYPE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9I7L4-1", "uniprot_id": "Q9I7L4_DROME", "id": "Q9I7L4-1", "name": "", "aln": "--------------------------------------MASTSRAARSQNAIPS----------------------------------------------------------------------QEAQQPVDVVDAKVRAILNYILDHTAQKIPIKDK-----DLIAVAGDKSELKKRLPLVTN--LLAETFGIILTPLDATTKTFI---CTAEEPVASIHELTPAQ-RPQFTLLYIILMYIFLRGNRIEDSKLYVMLEMLNIYPDEEHGYFGPNLRKQIEETFVKQQYLKRERSQLSAYDDSKTFFLWGPRAKAEFTFEQMVQFASKLLNQHPKVFGHHLSMAQEGVNAE-----------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q05541-1", "uniprot_id": "NSE3_YEAST", "id": "Q05541-1", "name": "Non-structural maintenance of chromosome element 3", "aln": "MSSIDNDSDVDLTEDLAVAKIVKENPVAR-KMVRYILSRGESQNSIITRNKLQS--------------------------------------------VIHEAAREENIAKPSFS-----KMFMDINAILYNVYGFELQGLPSKNNMNAGGNGSNSNTNKSMPEPLGHRAQKFILLNNVPHSKNFDDFKILQSAHTYEELIVTGEYIGDDIASGTSNTLESKLSTDRDLVYKGVLSVILCIVFFSKNNILHQELIKFLETFGIPSDGSKIAILNITIEDLIKSLEKREYIVRLE-EKSDTDGEVISYRIGRRTQAELGLESLEKLVQEIMGLEKEQTKSLHDDIIKSIGDSYSI--------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : * : . . :: : . : : .. : : : : : . :: .: : :: : :* :* :*: .. : *: :.: . . : : : : :. *: : . * : * *: ** .: :: .: . . .. ", "identical_positions": 11, "similar_positions": 62, "identity": "2.89%" }, { "cls_id": "homologset.agr.MGI:1333828", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6NVD9-1", "uniprot_id": "BFSP2_MOUSE", "id": "Q6NVD9-1", "name": "Phakinin", "aln": "MSKRRVAADLPSGTNSSMPVQRHRVSSLRGTHSPSSLDSPPASRTSAVGSLVRAPGVYVGVAPSGGIGGLGARVTRRALGISSVFLQGLRSSGLANVPAPGPERDHTTVEDLGGCLVEYMTKVHALEQVSQELETQLRAHLESKAKSSGGWDALRASWASSYQQVGEAVLENARLLLQMETIQAGADDFKERYENEQPFRKAAEEEVSSLYKVIDEANLTKTDLEHQIESLKEELGFLSRSYEEDVKVLYKQLAGSELEQADVPMGTGLDDVLETIRVQWERDVEKNRAEAGALLQAKQQTEVVHVSQTQEEKLAAALSVELHDTSRQVQSLQAETESLRALKRGLENSLHDAQHWHDMELQNLGAVVGRLEAELAEIRSETEQQQQERAHLLACKSQLQKDVASYHALLDREENN-----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZER2-1", "uniprot_id": "BFSP2_RAT", "id": "D3ZER2-1", "name": "Phakinin", "aln": "MSERRVAMDLPSGSNASMPLQRHRVSSLRGTRSPSSLDSPPASRTSAVGSLVRAPGVYVGVAPSGGIGGLGARVTRRALGISSVFLQGLRSSGLATAPAPGPERNHATAEDLGGCLVEYMTKVHALEQVSQELETQLRAHLESKAKRSGGWDALRASWASSYQQVGEAVLENARLMLQMETIQAGADDFKERYENEQPFRKAAEEEVSSLYKVIDEANLTKTDLEHQIESLKEELGSLSRSYEEDVKVLYKQLAGSELEQTDVPMGTGLDDVLETIRVQWERDVEKNRAEAGAVLQAKQQTEVVHVSQTQEEKLAAALSVELHDTSRQVQSLQAETESLRALKRGLENTLHDAKHWHDMELQNLGAVVGRLEAELAEIHSETEQQQQERAHLLACKGQLQKDVASYHALLDREESN-----------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q13515-1", "uniprot_id": "BFSP2_HUMAN", "id": "Q13515-1", "name": "Phakinin", "aln": "MSERRVVVDLPTSASSSMPLQRRRAS-FRGPRSSSSLESPPASRTNAMSGLVRAPGVYVGTAPSGCIGGLGARVTRRALGISSVFLQGLRSSGLATVPAPGLERDHGAVEDLGGCLVEYMAKVHALEQVSQELETQLRMHLESKATRSGNWGALRASWASSCQQVGEAVLENARLMLQTETIQAGADDFKERYENEQPFRKAAEEEINSLYKVIDEANLTKMDLESQIESLKEELGSLSRNYEEDVKLLHKQLAGCELEQMDAPIGTGLDDILETIRIQWERDVEKNRVEAGALLQAKQQAEVAHMSQTQEEKLAAALRVELHNTSCQVQSLQAETESLRALKRGLENTLHDAKHWHDMELQNLGAVVGRLEAELREIRAEAEQQQQERAHLLARKCQLQKDVASYHALLDREESG-----------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A286YA92-1", "uniprot_id": "A0A286YA92_DANRE", "id": "A0A286YA92-1", "name": "", "aln": "-----------------MPLPRRRSS-FLGQGAAERPGS--VGRMSAAATSAPR-GVFVGNAPTGGGSSLGTRVSRRALGISSVFLQGLRCSSVPVVAQPGEQGHPFGVDSLNTCLLEYRDKVHALEQLNKQLEEQIRHCLDRKAVSAGTWTGLKQDWEDVYIQVSEAILYNARLMLQTENVQANAEDFKERYENEQPFRKAVEEEINSLYKVIDDANLTRMDLENEIESMKTELINVEQSHMEDVKMLYKQMSGREVDEPDAPTETSLDQILSFIRSHWERVVEKNRAETYAYFECKQAGSLN-SKLSQEEEEMECLKTECNDAGCKIQNLQAETESIRALKRGLENALNDAKHWHDIELQNLGSVIGKLEAELTDIRGDIEQQRRDYETLLNNKMKVEMEIGTYHGILDGEESRFYTSTFPAGSSVPEGPTDPTPSTSGQQSCAQTDGSSAPEAPEEKNKF", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **: *:* * : * :.. * ..* .* . . **:** **:* ..**:**:***************.*.:. .. ** : . .:.*. **:** *******:.::** *:* *: ** :* * .*: .* . **.**:* ****:** *.:**.*:***************.***:.*******:****: *** :***:* ** :.:.: ****:*:**::* *::: *.* *.**::*. ** :*** *****.*: * ::.** .: . :***: .* .* :::. ::*.*******:*********:*:**:****:******:*:*:***** :*:.: ***::: ** * ::: ::.:**.:** **. ", "identical_positions": 198, "similar_positions": 117, "identity": "42.76%" }, { "cls_id": "homologset.agr.MGI:1333829", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q2PRE2-1", "uniprot_id": "Q2PRE2_DANRE", "id": "Q2PRE2-1", "name": "", "aln": "-----------------------------------MENLSIIVSFELTLDPFFIPPGAKYPIFIFGIFIYMFAAFCNLTLLLLIILTKSLHKPMYFILFSLPLNDFVGITSMLPKVLSDILTETNN--MYYPLCVLQGFLLHMYGGGVMFVLAAMAFDRYIAICMPLRYNALMTPRAVMTVVALVWGLVFLIICVLFSLHGLHSRC-RSHIVS-LFCDNPSLLKLACGD-TTINNIYGLFLTAIMQIITISIQAFSYVKILITCLTTRRSDAKSKAINTCVAQLVIFITFEIVVTFYLLSHRFSNVNANLQKIMGMLIFLVPPIMNPIVYGLNSHEIRKHILKTFHRKTSV-------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q2PRI0-1", "uniprot_id": "Q2PRI0_DANRE", "id": "Q2PRI0-1", "name": "", "aln": "-----------------------------------MDNLTLTNNVVLVEG-LKVTLQSSYPAFILLLLIYVFTMGCNIGLTILILTQKNLHNPMHFLFCNMPVNDIIGSTVIMPRLLQGILREASQRYMTYTECVVQAFFVHVFASVSHSVLIIMAFDRYVAICKPLRYAAIMSNKMVVRLSALAWGVSVIAVTVMIALSLRLSRC-RSYIEN-PFCDNASLFKLSCEEGVVINNLFGIFSTVVMFTFSLGSVFVTYGKIAASFRNRKHNSFNSKAMKTCGTHIALYLIMFVSCAIMIFLHRSP-QHSENRKLASIMFHIAPPGLNPLVYGLQTKEIRQNTSKLCSRNKVNVK-----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q15617-1", "uniprot_id": "OR8G1_HUMAN", "id": "Q15617-1", "name": "Olfactory receptor 8G1", "aln": "-----------------------------------MSGENNSSVTEFILAGLSEQPELQLPLFLLFLGIYVVTVVGNLGMTTLIWLSSHLHTPMYYFLSSLSFIDFCHSTVITPKMLVNFVTEKNI--ISYPECMTQLYFFLVFAIAECHMLAAMAYDRYMAICSPLLYSVIISNKACFSLILGVYIIGLVCASVHTGCMFRVQFC-KFDLINHYFCDLLPLLKLSCSS-IYVNKLLILCVGAFNILVPSLTILCSYIFIIASILHIRSTEGRSKAFSTCSSHMLAVVIFFGSAAFMYLQPSSISSMDQ-GKVSSVFYTIIVPMLNPLIYSLRNKDVHVSLKKMLQRRTLL-------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NG78-1", "uniprot_id": "OR8G5_HUMAN", "id": "Q8NG78-1", "name": "Olfactory receptor 8G5", "aln": "MIIYKQGITFLQKENNNTIHLNTMFFLSPAETHQRMAAENHSFVTKFILVGLTEKSELQLPLFLVFLGIYVVTVLGNLGMITLIGLSSHLHTPMYCFLSSLSFIDFCHSTVITPKMLVNFVTEKNI--ISYPECMTQLYFFLVFAIAECHMLAAMAYDGYVAICSPLLYSIIISNKACFSLILVVYVIGLICASAHIGCMFRVQFC-KFDVINHYFCDLISILKLSCSS-TYINELLILIFSGINILVPSLTILSSYIFIIASILRIRYTEGRSKAFSTCSSHISAVSVFFGSAAFMYLQPSSVSSMDQ-GKVSSVFYTIVVPMLNPLIYSLRNKDVHVALKKTLGKRTFL-------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9EQB8-1", "uniprot_id": "Q9EQB8_MOUSE", "id": "Q9EQB8-1", "name": "Olfactory receptor", "aln": "--------------------------------MNDMTSGNYCTVTEFFLAGLSEKPELQLPLFFLFIGIYMITVAGNLGMIILIGLSSHLHTPMYYFLSSLSFIDFCQSTVVTPKMLVNFVTEKNI--ISYPGCMTQLYFFLIFAIAECYILAAMAYDRYVAICNPLLYNVTMSYQIYIFLISGVYIIGVICASAHTGFMVRIRFC-KLDVINHYFCDLLPLLKLACSN-TYINEMLILFFGTLNIFVPILTIITSYIFIIASILRIRSTEGRSKAFSTCSSHILAVAVFFGSLAFMYLQPSSVSSMDQ-GKVSSVFYTIVVPMLNPLIYSLRNKDVAVALKKIIERKTFM-------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0L5F2-1", "uniprot_id": "A0ABK0L5F2_RAT", "id": "A0ABK0L5F2-1", "name": "Olfactory receptor", "aln": "--------------------------------MEDMAAGNHCTVTEFFLAGLSEKPGLQLPLFLLFIGIYLITVAGNLGMILLIGLSSHLHTPMYYFLSSLSFIDFCQSTVVTPKMLVNFVTEKNI--ISYPGCMTQLYFFLIFAIAECYILAAMAYDRYVAICNPLLYNVTMSYQIYISLISGVYIIGVICASAHTGLMVRIRFC-KLDVINHYFCDLLPLLKLACSS-TYINEMLILFFGTLNIFVPILTIITSYIFIIASILRIRSTEGRSKAFSTCSSHILAVAVFFGSLAFMYLQPSSVSSMDQ-GKVSSVFYTIVVPMLNPLIYSLRNKDVSIALKKILERKTFM-------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q2PRK1-1", "uniprot_id": "Q2PRK1_DANRE", "id": "Q2PRK1-1", "name": "", "aln": "---------------------------MSSIQSNSSANETFVRPAKFFLSGLSNVPHVKY-YYVFLSLVYVVTVLGNSFLMCTIYLARRLHTAKYIVVFHLAFSDLCGSSAVIPKTIDTFLFDHQD--ISYEACLANTFFIYHFLNIQSLTLLVMAYDRLVAICFPLHYHAIITKAAMFLILGGMWIFSVTHISVFVGLLNRLSFCRSTV-IDSYFCDYSLINRLACND-NSLNILMIKINFGLLLCAPLILIFVSYFCISLALFKIAHGADRVKAIKTCTSHLMLVVVGYTPLISNQIAVLTAPMPANIRLINNCLTQVIPPMLNPIIYTLKTDEVMQSIKELYNGR-NVKNIGQMKCTRRYSKQK---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q2PRK0-1", "uniprot_id": "Q2PRK0_DANRE", "id": "Q2PRK0-1", "name": "", "aln": "---------------------------MSFIQSNSSANETFVRPATFFLSGLSNVPHAKY-YYVFLSLVYVATVLGNSFIMCVIYMSRRLHTAKYIVVFHLAFSDLCGSSTVIPNVIDTFLFDHQE--ISYEACLANTFFTYHFMNLQSLTLLVMAYDRLVAICFPLQYHAIVTNAAMFSILGGMWIFSVTHFSVFVGLLNRLSFCKSNV-IDSYFCDYSLINRLACND-NSVNIMMVKINFGLLICTPLILIFISYFCISLALFKIAHGVDRAKAIKTCTSHLMLVAIFFIPFLSNQIAILTTSVHLNTRLINSSLTQAIPPMLNPIIYTLKTDEVMQSVKELYKRKVNTTTERRMKWNSRNSKQKIQV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q2PRK5-1", "uniprot_id": "Q2PRK5_DANRE", "id": "Q2PRK5-1", "name": "", "aln": "------------------------------MNQDFVGNGNVSTPSYFYISGFSGIPHMRY-YYIFLFFIYIITVLGNSCLMSVIIMDRNLHTPKYIAVFNLSLTDICESTAVIPQLLDTFLFGNQM--MPYGLCMSSMFSVLLFLAMQSLTLTVLSFDRFVAISLPLRYHMIVTQRLMLIIIAASWTLALLLMIIGAIFMSRLSFCKVIVTVNSFYCDHGPIYRSACNN-NFPSSVIASLFPAVILGFPAFFIIFSYTCIAVTLFRITTPQDRQRATKTCMAHLILVAVFYVPIT--FTYAFWSFIDTNTRIINLSLTSALPPMLNPIIYTFMTEEFMVAVKRLFKRR-NIFPSWK--------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : :.. :*: : * : * **.. : . :.. *: : : *. : :: . : * *: . : : * :::* :**. ** * :: . : : . . * . :** : : :* . . : . . :* * : . :* .** ::: : : : * :**::* : ..:. . . ", "identical_positions": 29, "similar_positions": 73, "identity": "7.84%" }, { "cls_id": "homologset.agr.MGI:1333830", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9EPJ3-1", "uniprot_id": "RT26_RAT", "id": "Q9EPJ3-1", "name": "Small ribosomal subunit protein mS26", "aln": "MLRA----LNR--LAARPGGQPP-TLLLLPVRGRKTRHDPPAKSKVGRVKMPPAVDPAELFVLTERYRQYRETVRALRREFTLEVRGKLHEARAGVLAERKAQEAIREHQELMAWNREENRRLQELRIARLQLEAQAQELRQAEVQAQRAQEEQAWVQLKEQEVLKLQEEAKNFITRENLEARIEEALDSPKSYNWAVTKEGQVVRN--------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80ZS3-1", "uniprot_id": "RT26_MOUSE", "id": "Q80ZS3-1", "name": "Small ribosomal subunit protein mS26", "aln": "MLRA----LNR--LAARPETRPP-TPLLLPVRGRKTRHDPPAKSKVGRVQTPPAVDPAEFFVLTERYRQYRETVRALRLEFTLEVRRKLHEARAGVLAERKAQQAITEHRELMAWNRDENRRMQELRIARLQLEAQAQEVQKAEAQAQRAQEEQAWVQLKEQEVLKLQEEAKNFITRENLEARIEEALDSPKSYNWAVTKEGQVVRN--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BYN8-1", "uniprot_id": "RT26_HUMAN", "id": "Q9BYN8-1", "name": "Small ribosomal subunit protein mS26", "aln": "MLRA----LSR--LGAGTPCRPR-APLVLPARGRKTRHDPLAKSKIERVNMPPAVDPAEFFVLMERYQHYRQTVRALRMEFVSEVQRKVHEARAGVLAERKALKDAAEHRELMAWNQAENRRLHELRIARLRQEEREQEQRQALEQARKAEEVQAWAQRKEREVLQLQEEVKNFITRENLEARVEAALDSRKNYNWAITREGLVVRPQRRDS---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DH29-1", "uniprot_id": "Q6DH29_DANRE", "id": "Q6DH29-1", "name": "Small ribosomal subunit protein mS26", "aln": "MLRA----LSRCPLPAVRLLAPRSAVLVESVRGRKSRTDPQAKSKIGRIKTPPPVDPVEMITMKERYTEYNLILKALRLEFRENMLRKRYEEEVGSVAEERAKRDAEEHKSLMAWNDAENHRLQVIREQRVQKEAEAAEEKRKEAAMLHQQELENYIKEKERQILQLQEEAKNFITLDNLDQRIEEALDNPINYNFAIDKQGRVVKRTAFQ----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VVN2-1", "uniprot_id": "RT26_DROME", "id": "Q9VVN2-1", "name": "Small ribosomal subunit protein mS26", "aln": "MLRAGCQLLTQSTLPTGKTVGNSFALEFVRWR-RKPRWLPVAKSKMFRVPERKKQSEEERTELMRLHNQYKTQLRSVRQFLREEVVRHEETSTADHIVLT-PEQEEAEFQKCLDANAAWNAAIAKERDQRLAKKREEKVAYIQERLEAQQLREEERKEQANQRVLLEIERSKNYITRENLDAAIETALANPVDHNFAIDMAGNLYHGRSTSQLPDATPEPNQQVLSN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**** *.: * : : . * **.* * ****: *: . * : . : .*. ::::* : :: : .. :. . . *.:. : * * : * *: : . : . : : ::.:* *. **:** :**: :* ** . .:*:*: * : : ", "identical_positions": 38, "similar_positions": 56, "identity": "16.74%" }, { "cls_id": "homologset.agr.MGI:1333831", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8WWA0-1", "uniprot_id": "ITLN1_HUMAN", "id": "Q8WWA0-1", "name": "Intelectin-1", "aln": "-------MNQLSFLLFL-----------IATTRG-----------WSTDEAN------TYFKEWTCSSSP---SLPRSCKEIKDECPSAFDGLYFLRTENGVIYQTFCDMTSGGGGWTLVASVHENDMRGKCTVGDRWSSQQGSKAVYPEGDGNWANYNTFGSAEAATSDDYKNPGYYDIQAKDLGIWHVPNKSPMQHWRNSSLLRYRTDTGFLQTLGHNLFGIYQKYPVKYGEGKCWTDNGPVIPVVYDFGDAQKTASYYSPYGQREFTAGFVQFRVFNNERAANALCAGMRVTGCNTEHHCIGGGGYFPEASPQQCGDFSGFDWSGYGTHVGYSSSREITEAAVLLFYR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8WWU7-1", "uniprot_id": "ITLN2_HUMAN", "id": "Q8WWU7-1", "name": "Intelectin-2", "aln": "MLSMLRTMTRLCFLLFF-----------SVATSG-----------CSAAAASSLEMLSREFETCAFSFS----SLPRSCKEIKERCHSAGDGLYFLRTKNGVVYQTFCDMTSGGGGWTLVASVHENDMRGKCTVGDRWSSQQGNKADYPEGDGNWANYNTFGSAEAATSDDYKNPGYYDIQAKDLGIWHVPNKSPMQHWRNSALLRYRTNTGFLQRLGHNLFGIYQKYPVKYRSGKCWNDNGPAIPVVYDFGDAKKTASYYSPYGQREFVAGFVQFRVFNNERAANALCAGIKVTGCNTEHHCIGGGGFFPQGKPRQCGDFSAFDWDGYGTHVKSSCSREITEAAVLLFYR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E9PT30-1", "uniprot_id": "E9PT30_RAT", "id": "E9PT30-1", "name": "", "aln": "----MPFFLNCGYIIYIPEHIKTSVPTEMMPLRCRLGAYYLLKKLACGAKED------PETNKGTHSFFD---SLFRSCKEIKEENTRAQDGLYFLRTENGVIYQTFCDMTTAGGGWTLVASVHENNMGGKCTVGDRWSSQQGNRADYPEGDGNWANYNTFGSAEGATSDDYKNPGYFDIQAENLGIWHVPNNSPLHNWRNSSLLRYRTFTGFLQHLGHNLFGLYQKYPVKYGVGKCWTDNGPALPVVYDFGDAQKTASYYSPYGQREFTAGFVQFRVYNNERAASALCAGVRVTGCNSEAHCIGGGGFFPEGNPRQCGDFGAFDWNGYGTHTGYSSSRAITEAAVLLFYR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88310-1", "uniprot_id": "ITL1A_MOUSE", "id": "O88310-1", "name": "Intelectin-1a", "aln": "-------MTQLGFLLFI-----------MVATRG-----------CSAAEEN------LDTNRWGNSFFS---SLPRSCKEIKQEHTKAQDGLYFLRTKNGVIYQTFCDMTTAGGGWTLVASVHENNMRGKCTVGDRWSSQQGNRADYPEGDGNWANYNTFGSAEAATSDDYKNPGYFDIQAENLGIWHVPNKSPLHNWRKSSLLRYRTFTGFLQHLGHNLFGLYKKYPVKYGEGKCWTDNGPALPVVYDFGDARKTASYYSPSGQREFTAGYVQFRVFNNERAASALCAGVRVTGCNTEHHCIGGGGFFPEGNPVQCGDFASFDWDGYGTHNGYSSSRKITEAAVLLFYR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ACD6B6A1-1", "uniprot_id": "A0ACD6B6A1_DANRE", "id": "A0ACD6B6A1-1", "name": "", "aln": "---MFSELIILSLSFWFCN---------TAQTNQ--------QETSSTNIDD------VSINPEIAKFVDRIKYVGRSCKEIRDKYHVYEDGLYYLISSRGVLYQTFCDMTTAGGGWTLVASVHENNMYGKCTVGDRWSSEQGSNENRPIGEGTWANKVTFGAAEAATSDDYKNPGYYDIAAQDVSVWHVPNNMELEHWSTGSILRYHTENHFLTLHGGNLFKLFMKFPVRFGIGSCNIDNGPAVPIVYDTGNEESTKKLYGPSARTQFEPGFITFRVLNYEKAAMALCSGAKPTGCNTEHFCIGGGGHFPEGYPKQCGDFTGFDWNGYGTNTEWSASRELTEAAVLLFYR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1NUF6-1", "uniprot_id": "A0A8M1NUF6_DANRE", "id": "A0A8M1NUF6-1", "name": "", "aln": "---MLRCLFVFVCLLHT-----------MLGVMG-----------AVTPKPIIING--TYINPELGKYHARLRSIARSCLQIKKNHGATQDGMYILTTESGTYYQTFCDMTTAGGGWTLVASVHENNINGKCSFGDRWSSQQGNDQSLPEGEASWANTATFGSAEGSTSDDYKNPGYYDISAQDVSVWHVPNNEQLKKWTSSAILRYHTESQFLKEHGGNLYHLFKKYPVRFGAGQCKSDMGPSSSVVYDTGDKDSTSNLYGPSVRNEFESGFITFRVFNTDQSAMAMCSGIKPSGCNTQHYCIGGGGFFAQ--PEQCGDFTALDLK--------ETFKQPTQSAVLLFYR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AC58JFF1-1", "uniprot_id": "A0AC58JFF1_DANRE", "id": "A0AC58JFF1-1", "name": "", "aln": "------MMQSAGFLLLC------------VPLIS----------LLCESILS-----LPTGKTPTGEFPES--VTARSCRELLKKYGHKKDGLYYLRSKDNEVYQTYCDMSTNGGGWTLVASVHENNIHGSCTVGDRWTSQQGSSSYHPAGDGSWSNKVLFGTAEAATNDDYKNPGYYDIKAKDIAVWHVHNDNELEFWKVASVLRYHTNSNFLTPFGGNLYHFFKKYHLQYGIGTCN-DRGISVPIVYDIGSDMRVNELYGESVRADFDTGYVTFRVFNNYQEAYAMCSGVRPKGCYAQYYCIGGGGYFPN---TFCSDFAYLNANN-GATNGYGASKEIINAAVFIFYR", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : . *** :: .. **:* * :. . ***:***:: *************:: *.*:.****:*:**. * *:..*:* **:**.:*.********:** *:::.:*** *. :. * .::***:* . ** * **: :: *: ::: * * * * .:*** *. . . *. : :* .*:: *** * : * *:*:* : .** :: .******.*.: *.** :: . : ::**::***", "identical_positions": 106, "similar_positions": 83, "identity": "30.2%" }, { "cls_id": "homologset.agr.MGI:1333833", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0M6K1-1", "uniprot_id": "A0ABK0M6K1_RAT", "id": "A0ABK0M6K1-1", "name": "", "aln": "MVGVPG------------------AAAFQLGCEKRVPAMPGSPVEVKIQSRASPPIMPPLPPINPGGPRPVSFTPTALSNGISHSP------------------------------------------------------------------------------PTLNGAPS-----------PPQRFSNGPASSTSSALTNQQLPATCGARQLSKLKRFLTTLQQFGNDIS-PEIGEKVRTLVLALVNSTVTIEEFHCKLQEATNFPLRPFVIPFLKANLPLLQRELLHCARAAKQTPSQYLAQHEHLLLNTS--IASPADSSELLMEVHGNGKRPSPESFFYRRDENNF-ERDTVPPEPTAKRVCTISPAPRHSPALTVPLLSAGGQFHPTPPPLQHYTLEDIATSHLYREPN--KMLEHREVRERHHNLSLNGGYQDELVDHRLTEREWADEWKHLDHALNCIMEMVEKTRRSMAVLRRCQESDREELNYWKRRCNENTELRKTGTELV----SRQHSPGSTDSLSNDSQREFTSRPAAGYVPVEFWKKTEEAVNKVKIQAMSEVQKAVAEAEQKAFEVIATERARMEQTIADVKRQAAED--------AFLVINEQEESTENCWNCGRKASETCSGCNIARYCGSFCQHKDWERHHRLCG--QSLHGHSPHSQSRSLLPGGRGS-ARSADCSVPSPALDKTSATTSRSSTPASVTAIDANGL-----------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70374-1", "uniprot_id": "MTG8R_MOUSE", "id": "O70374-1", "name": "Protein CBFA2T2", "aln": "MVGVPG------------------AAAFQLGCEKRVPAMPGSPVEVKIQSRSSPPIMPPLPPINPGGPRPVSFTPTALSNGINHSP------------------------------------------------------------------------------PTLNGAPS-----------PPQRFSNGPASSTSSALTNQQLPATCGARQLSKLKRFLTTLQQFGNDIS-PEIGEKVRTLVLALVNSTVTIEEFHCKLQEATNFPLRPFVIPFLKANLPLLQRELLHCARAAKQTPSQYLAQHEHLLLNTS--IASPADSSELLMEVHGNGKRPSPE----RRDENNF-ERDTVPPEPPAKRVCTISPAPRHSPALTVPLMNPGGQFHPTPPPLQHYTLEDIATSHLYREPN--KMLEHREVRERHHNLSLNGGYQDELVDHRLTEREWADEWKHLDHALNCIMEMVEKTRRSMAVLRRCQESDREELNYWKRRFNENTELRKTGTELV----SRQHSPGSTDSLSNDSQREFTSRPATGYVPVEFWKKTEEAVNKVKIQAMSEVQKAVAEAEQKAFEVIATERARMEQTIADVKRQAAED--------AFLVINEQEESTENCWNCGRKASETCSGCNIARYCGSFCQHKDWERHHRLCG--QSLHGHSPHSQSRPLLPGGRGS-ARSADCSVPSPALDKTSATTSRSSTPASVTAIDANGL-----------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43439-1", "uniprot_id": "MTG8R_HUMAN", "id": "O43439-1", "name": "Protein CBFA2T2", "aln": "MAKESGISLKEIQV---------LARQWKVGPEKRVPAMPGSPVEVKIQSRSSPPTMPPLPPINPGGPRPVSFTPTALSNGINHSP------------------------------------------------------------------------------PTLNGAPS-----------PPQRFSNGPASSTSSALTNQQLPATCGARQLSKLKRFLTTLQQFGNDIS-PEIGEKVRTLVLALVNSTVTIEEFHCKLQEATNFPLRPFVIPFLKANLPLLQRELLHCARAAKQTPSQYLAQHEHLLLNTS--IASPADSSELLMEVHGNGKRPSPE----RREENSF-DRDTIAPEPPAKRVCTISPAPRHSPALTVPLMNPGGQFHPTPPPLQHYTLEDIATSHLYREPN--KMLEHREVRDRHHSLGLNGGYQDELVDHRLTEREWADEWKHLDHALNCIMEMVEKTRRSMAVLRRCQESDREELNYWKRRYNENTELRKTGTELV----SRQHSPGSADSLSNDSQREFNSRPGTGYVPVEFWKKTEEAVNKVKIQAMSEVQKAVAEAEQKAFEVIATERARMEQTIADVKRQAAED--------AFLVINEQEESTENCWNCGRKASETCSGCNIARYCGSFCQHKDWERHHRLCG--QNLHGQSPHGQGRPLLPVGRGSSARSADCSVPSPALDKTSATTSRSSTPASVTAIDTNGL-----------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13A7B7-1", "uniprot_id": "A0AB13A7B7_DANRE", "id": "A0AB13A7B7-1", "name": "", "aln": "MVGIPG--------------------AFQYSAEKKVPAMPGSPVDAKTHSRPTVSVMPPLPSVNPSGPRPAAFSTTALTNGINHSP------------------------------------------------------------------------------PMLNAIPS-----------PPQRYSNGPSSSSSSSLANQQLPATCGARQLSKLKRFLTTLQQFGNDIS-PEIGESVRNLVLALVNSTVTIEEFHSRLQEATNFPLRPFVIPFLKANLPLLQRELLHCARAAKQTPAQYLSQHEHLLLSTT--VPSPADSSELLLEPS-DSKRHSPN----RSKENGFHDRPPASLEPPAKRICTISPAPRHSPAHPLQLP---AQIHPTPPPLQHYALEDISSAQLYREPQ--RILELKE---RPRLTGSNGGYREEPVDHRLTEREWAEEWRHLDHVLNSIVDMVEKTRRSVSVLRRCQESDREELNFWRRRSNPHDEGRKNGNTPVNIPFSKTHSPLSAEGVNADSPRDVPLRASSGYVPDEIWRKAEEAVNEVKRQAMDEVQKAVAEAEQKAFEMITAERAKMEKTLAEAKRKATED--------AIQVINEQEDSSECCWNCGRKASETCSGCNAARYCGSFCQHKDWERHHLICS--PGLQNQ-PKTMSR-----------SQAKTPIPSPSLEKNSSRASTPSTPASASTPDTSAH-----------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KEZ2-1", "uniprot_id": "A0A0B4KEZ2_DROME", "id": "A0A0B4KEZ2-1", "name": "", "aln": "MMALDGKAIIKEEITDKDAYDAAAAAAAAVAAGAALAVASAAAVQVPPASSSSAGSASSAAAAATNNTTSAAATAAAISRRLKASSSGGDKSSTSSSSSKDSSHTSSSRSERDRERERERERERDRLCRTPPDSPPDSSRSLAPRSPHSPLQLHQHPQRNASVSPVVNGSSSGGGGVGSSGTSPTPTPGSQHAASLAAAAAAAAAAHVEQARLVSKMRKFLGALVQFSQELGQPEVCERVRALVLSLCSGSISVEEFRLALQEAINLPLRPYVVPLLKNSIALVQREILALARATNQSALQYVTNNEQAVMEFAPHGVASAEFGDIFIQLEAPTSNGSSAVFKRRSSDSMMEHGGHNGLQEWNEYMASGGAGYPPPPSKRLTLHPAHSVVAYGEYGVSSAEGLPSAAAFMQRDERDLRMSEAQARHAAPPQRAGNPQPNPNAAAPGAPGAGGEEEWKNIHTMLNCISAMVDKTKRAITILQQRG--------------------------------IEPQHPNSGQEVTPAAMAELRR--QTEEKVAEFKRNAEDAVTQVKRQAVIEIQRAVVAAETRAAEIMTQERLRMEKFFMEMSRHSSGERDLDNKSPSMASAQNGSNLQQQCWNCGRKATETCSGCNMARYCSASCQYRDWDSHHQVCGNTRASELSAKHLHSASNLSLRNAMATRSPPTPNSAAHLQAAAAAAAAAAGAREAVSAPVGGPGAGIAVGTGAGSGGQSGGGGGGGGGGGGGAAAAAVAAATPGALVANGLGSKXRIRMMKPKKKYLC", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * . :.. ..:.*:. * .: .. .. .... ..: :.:*::. :. *. * :*. .* *. .. ::* ::: : . . ** :**:::** :* **.:::. **: * ** ***:* ..::::***: **** *:****:*:*:** .:.*:***:* ***::*:. **::::*: ::. : :.*: .::::: .. *. * .:. : . : : :.: ... .*: : * . . :. ::: : *: . :: * : . * . : . . :**:::. **.* **:**:*::::*:: . : * * : :. : :. : *: :::*:**.:** **: *:*:**. ** :* *::: ** :**: : : .*::: : :: :: .: : ********:******* ****.: **::**: ** :*. . : . .. . .:. *: :: :: .: . .. : ... ", "identical_positions": 126, "similar_positions": 218, "identity": "15.93%" }, { "cls_id": "homologset.agr.MGI:1333834", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O89006-1", "uniprot_id": "O89006_MOUSE", "id": "O89006-1", "name": "", "aln": "MADSRNTQYCSLQESAQAQ---QELDNDQETMETSEEEEDTTTSNKVYGSGIPS----------------------------PPQSPQRAYSPCVALASIPDSPSEEASIKG-------SGGLEDPLYLLHNAQNTKVYDLVDFLVLNYQMKAFTTKA-----EMLESIGREYEEYYPLIFSEASECLKMVFGLDMVEVDPSVHSYI---LVTALGITYDGMMTDVQGMPKTGILIAVLSVIFMKGNYVSEEIIWEMVNNIGLCGGRDP-YIHKDPRKLISEEFVQEGCLKYR--QVPNSDPPSYGFLWGPRAFAETSKMKVLQFFASINKTHPRAYPEKYAEALRDEIYRTKAWILN---------RCSNFSDLLTF--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZW04-1", "uniprot_id": "D3ZW04_RAT", "id": "D3ZW04-1", "name": "", "aln": "MDDAHNIQYSNLQDNAQAE---QELDNAQATMAAAEEEEATSTSKAEYGSGIPS----------------------------PLQSPERACSPSVALASIPVGPSEEASIRQ-------LEALEDPLYLLHNAQNVKVYDLVDFLLFKYQTKAFTTKA-----EMLETIGREYDEYYPLIFSEASECMKLVFGLDIVEVDPSVHSYV---LVTALGITYDGMLTDVQGMPKTGVLIVVLGVIFMKGNYVSEDIIWEMLNNIGLCGGMDP-YIHRDPRKLISEEFVQEGYLEYR--QVPNSDPPSHVFLWGPRAFAETTKLKVLQFFASITKTHPRAYPEKYAEALRDEIDRVEAWIFQ---------QMLRHL-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P43363-1", "uniprot_id": "MAGAA_HUMAN", "id": "P43363-1", "name": "Melanoma-associated antigen 10", "aln": "MPRAPKRQRCMPEEDLQSQSETQGLEGAQAPLAVEEDASSSTSTSSSFPSSFPSSSSSSSSSCYPLIPSTPEEVSADDETPNPPQSAQIACSSPSVVASLPLDQSDEGSSSQKEESPSTLQVLPDSESLPRSEIDEKVTDLVQFLLFKYQMKEPITKA-----EILESVIRNYEDHFPLLFSEASECMLLVFGIDVKEVDPTGHSFV---LVTSLGLTYDGMLSDVQSMPKTGILILILSIVFIEGYCTPEEVIWEALNMMGLYDGMEH-LIYGEPRKLLTQDWVQENYLEYR--QVPGSDPARYEFLWGPRAHAEIRKMSLLKFLAKVNGSDPRSFPLWYEEALKDEEERAQDRIATTDDTTAMASASSSATGSFSYPE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9I7L4-1", "uniprot_id": "Q9I7L4_DROME", "id": "Q9I7L4-1", "name": "", "aln": "--------------------------------------MASTSRAARSQNAIPS----------------------------------------------------------------------QEAQQPVDVVDAKVRAILNYILDHTAQKIPIKDK-----DLIAVAGDKSELKKRLPLVTN--LLAETFGIILTPLDATTKTFI---CTAEEPVASIHELTPAQ-RPQFTLLYIILMYIFLRGNRIEDSKLYVMLEMLNIYPDEEHGYFGPNLRKQIEETFVKQQYLKRERSQLSAYDDSKTFFLWGPRAKAEFTFEQMVQFASKLLNQHPKVFGHHLSMAQEGVNAE-----------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q05541-1", "uniprot_id": "NSE3_YEAST", "id": "Q05541-1", "name": "Non-structural maintenance of chromosome element 3", "aln": "MSSIDNDSDVDLTEDLAVAKIVKENPVAR-KMVRYILSRGESQNSIITRNKLQS--------------------------------------------VIHEAAREENIAKP-----SFSKMFMDINAILYNVYGFELQGLPSKNNMNAGGNGSNSNTNKSMPEPLGHRAQKFILLNNVPHSKNFDDFKILQSAHTYEELIVTGEYIGDDIASGTSNTLESKLSTDRDLVYKGVLSVILCIVFFSKNNILHQELIKFLETFGIPSDGSKIAILNITIEDLIKSLEKREYIVRLE-EKSDTDGEVISYRIGRRTQAELGLESLEKLVQEIMGLEKEQTKSLHDDIIKSIGDSYSI--------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : * : . . :: : . : : .. : : : : : . :: .: : :: : :* :* :*: .. : :: :.: . . : : : : :. : : . * : * *: ** .: :: .: . . .. ", "identical_positions": 9, "similar_positions": 63, "identity": "2.37%" }, { "cls_id": "homologset.agr.MGI:1333837", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P43357-1", "uniprot_id": "MAGA3_HUMAN", "id": "P43357-1", "name": "Melanoma-associated antigen 3", "aln": "--------------------------------------------------------------------------------------------------------------MPLEQRSQHCKPEEGLEARGEALGLVGAQAPATEEQEAASSSST---------------------LVEVTLGEVPAA-ESPDPPQSPQGASSLPTTMNYPLWSQSYEDSSNQEEEGPSTFPD---LESEFQAALSRKVAELVHFLLLKYRAREPVTKAEMLGSVVGNWQYFFPVIFSKASSSLQLVFGIELMEVDPIGHLYI---FATCLGLSYDGLLGDNQIMPKAGLLIIVLAIIAREGDCAPEEKIWEELSVLEVFEGREDSILG-DPKKLLTQHFVQENYLEYR--QVPGSDPACYEFLWGPRALVETSYVKVLHHMVKISGGPHISYPPLHEWVLREGEE------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P43360-1", "uniprot_id": "MAGA6_HUMAN", "id": "P43360-1", "name": "Melanoma-associated antigen 6", "aln": "--------------------------------------------------------------------------------------------------------------MPLEQRSQHCKPEEGLEARGEALGLVGAQAPATEEQEAASSSST---------------------LVEVTLGEVPAA-ESPDPPQSPQGASSLPTTMNYPLWSQSYEDSSNQEEEGPSTFPD---LESEFQAALSRKVAKLVHFLLLKYRAREPVTKAEMLGSVVGNWQYFFPVIFSKASDSLQLVFGIELMEVDPIGHVYI---FATCLGLSYDGLLGDNQIMPKTGFLIIILAIIAKEGDCAPEEKIWEELSVLEVFEGREDSIFG-DPKKLLTQYFVQENYLEYR--QVPGSDPACYEFLWGPRALIETSYVKVLHHMVKISGGPRISYPLLHEWALREGEE------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P43358-1", "uniprot_id": "MAGA4_HUMAN", "id": "P43358-1", "name": "Melanoma-associated antigen 4", "aln": "--------------------------------------------------------------------------------------------------------------MSSEQKSQHCKPEEGVEAQEEALGLVGAQAPTTEEQEAAVSSSSP--------------------LVPGTLEEVPAA-ESAGPPQSPQGASALPTTISFTCWRQPNEGSSSQEEEGPSTSPD---AESLFREALSNKVDELAHFLLRKYRAKELVTKAEMLERVIKNYKRCFPVIFGKASESLKMIFGIDVKEVDPASNTYT---LVTCLGLSYDGLLGNNQIFPKTGLLIIVLGTIAMEGDSASEEEIWEELGVMGVYDGREHTVYG-EPRKLLTQDWVQENYLEYR--QVPGSNPARYEFLWGPRALAETSYVKVLEHVVRVNARVRIAYPSLREAALLEEEEGV----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P43361-1", "uniprot_id": "MAGA8_HUMAN", "id": "P43361-1", "name": "Melanoma-associated antigen 8", "aln": "--------------------------------------------------------------------------------------------------------------MLLGQKSQRYKAEEGLQAQGEAPGLMDVQIPTAEEQKAASSSST---------------------LIMGTLEEVTDS-GSPSPPQSPEGASSSLTVTDSTLWSQSDEGSSSNEEEGPSTSPDPAHLESLFREALDEKVAELVRFLLRKYQIKEPVTKAEMLESVIKNYKNHFPDIFSKASECMQVIFGIDVKEVDPAGHSYI---LVTCLGLSYDGLLGDDQSTPKTGLLIIVLGMILMEGSRAPEEAIWEALSVMGLYDGREHSVYW-KLRKLLTQEWVQENYLEYR--QAPGSDPVRYEFLWGPRALAETSYVKVLEHVVRVNARVRISYPSLHEEALGEEKGV-----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P43362-1", "uniprot_id": "MAGA9_HUMAN", "id": "P43362-1", "name": "Melanoma-associated antigen 9", "aln": "--------------------------------------------------------------------------------------------------------------MSLEQRSPHCKPDEDLEAQGEDLGLMGAQEPTGEEEETTSSSDS-------------------------KEEEVSAA-GSSSPPQSPQGGASSSISVYYTLWSQFDEGSSSQEEEEPSSSVDPAQLEFMFQEALKLKVAELVHFLLHKYRVKEPVTKAEMLESVIKNYKRYFPVIFGKASEFMQVIFGTDVKEVDPAGHSYI---LVTALGLSCDSMLGDGHSMPKAALLIIVLGVILTKDNCAPEEVIWEALSVMGVYVGKEHMFYG-EPRKLLTQDWVQENYLEYR--QVPGSDPAHYEFLWGSKAHAETSYEKVINYLVMLNAREPICYPSLYEEVLGEEQEGV----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P43364-1", "uniprot_id": "MAGAB_HUMAN", "id": "P43364-1", "name": "Melanoma-associated antigen 11", "aln": "METQFRRGGLGCSPASIKRKKKREDSGDFGLQVSTMFSEDDFQSTERAPYGPQLQWSQDLPRVQVFREQANLEDRSPRRTQRITGGEQVLWGPITQIFPTVRPADLTRVIMPLEQRSQHCKPEEGLQAQEEDLGLVGAQALQAEEQEAAFFSST---------------------LNVGTLEELPAA-ESPSPPQSPQEESFSPTAMDAIFGSLSDEGSGSQEKEGPSTSPDLIDPESFSQDILHDKIIDLVHLLLRKYRVKGLITKAEMLGSVIKNYEDYFPEIFREASVCMQLLFGIDVKEVDPTSHSYV---LVTSLNLSYDGIQCNEQSMPKSGLLIIVLGVIFMEGNCIPEEVMWEVLSIMGVYAGREHFLFG-EPKRLLTQNWVQEKYLVYR--QVPGTDPACYEFLWGPRAHAETSKMKVLEYIANANGRDPTSYPSLYEDALREEGEGV----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P43363-1", "uniprot_id": "MAGAA_HUMAN", "id": "P43363-1", "name": "Melanoma-associated antigen 10", "aln": "--------------------------------------------------------------------------------------------------------------MPRAPKRQRCMPEEDLQSQSETQGLEGAQAPLAVEEDASSSTSTSSSFPSSFPSSSSSSSSSCYPLIPSTPEEVSADDETPNPPQSAQIACSSPSVVASLPLDQSDEGSSSQKEESPSTLQVLPDSESLPRSEIDEKVTDLVQFLLFKYQMKEPITKAEILESVIRNYEDHFPLLFSEASECMLLVFGIDVKEVDPTGHSFV---LVTSLGLTYDGMLSDVQSMPKTGILILILSIVFIEGYCTPEEVIWEALNMMGLYDGMEHLIYG-EPRKLLTQDWVQENYLEYR--QVPGSDPARYEFLWGPRAHAEIRKMSLLKFLAKVNGSDPRSFPLWYEEALKDEEERAQDRIATTDDTTAMASASSSATGSFSYPE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZW04-1", "uniprot_id": "D3ZW04_RAT", "id": "D3ZW04-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------MDDAHNIQYSNLQDNAQAEQE-LDNAQATMAAAEEEEATSTS-----------------------------KAEYGS-GIPSPLQSPERACSPSVALASIPVGPSEEASIRQLEALED-------PLYLLHNAQNVKVYDLVDFLLFKYQTKAFTTKAEMLETIGREYDEYYPLIFSEASECMKLVFGLDIVEVDPSVHSYV---LVTALGITYDGMLTDVQGMPKTGVLIVVLGVIFMKGNYVSEDIIWEMLNNIGLCGGMDPYIHR-DPRKLISEEFVQEGYLEYR--QVPNSDPPSHVFLWGPRAFAETTKLKVLQFFASITKTHPRAYPEKYAEALRDEIDRVEAWIFQQMLRHL----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O89010-1", "uniprot_id": "O89010_MOUSE", "id": "O89010-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------MADFHNTQYCNLEESAQAQQE-SDNDQETMETSEEEEDTTTS-----------------------------NKVYGS-AIPSPPQSPQRAYSPCVALASIPDSPSEEASIKGSGGLED-------PLYLLHSAQNTKVYDLVDFLVLNYEMKAFPTKAEMLESIGREYEEYFPVIFSEASECLKMVFGLDMVEVDPSVHSYM---LVTALGITYDGMMTDVQGMPKTGILIAVLSVIFMKGNYVSEEVIWEMLNNIGLCGGRDPYIHK-DPRKLISEEFVQEGYLEYR--QVPNSDPPIYGFLWGPRALAETSKMKVLQFFASINKTHPRAYPEKYAEALRDEIERTKAWILSRCSNFSDHSSVLPFPF------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9I7L4-1", "uniprot_id": "Q9I7L4_DROME", "id": "Q9I7L4-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASTSRAARSQNAIPSQE------------AQQPVDVVDAKVRAILNYILDHTAQKIPIKDKDLIAVAGDKSE--LKKRLPLVTNLLAETFGIILTPLDATTKTFI---CTAEEPVASIHELTPAQ-RPQFTLLYIILMYIFLRGNRIEDSKLYVMLEMLNIYPDEEHGYFGPNLRKQIEETFVKQQYLKRERSQLSAYDDSKTFFLWGPRAKAEFTFEQMVQFASKLLNQHPKVFGHHLSMAQEGVNAE-----------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q05541-1", "uniprot_id": "NSE3_YEAST", "id": "Q05541-1", "name": "Non-structural maintenance of chromosome element 3", "aln": "--------------------------------------------------------------------------------------------------------------MSSIDNDSDVDLTEDLAVAKIVKENPVARKMVR---------------------------------------------YILSRGESQNSIITRNKLQSVIHEAAREENIAKPSFSKMFMDINAILYNVYGFELQGLPSKNNMNAGGNGSNSNTNKSMPEPLGHRAQKFILLNNVPHSKNFDDFKILQSAHTYEELIVTGEYIGDDIASGTSNTLESKLSTDRDLVYKGVLSVILCIVFFSKNNILHQELIKFLETFGIPSDGSKIAILNITIEDLIKSLEKREYIVRLE-EKSDTDGEVISYRIGRRTQAELGLESLEKLVQEIMGLEKEQTKSLHDDIIKSIGDSYSI--------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . : : : : . : .: : : .* :* : .. : * : : . . . : : :. *: : . : : * :: * .: . ", "identical_positions": 6, "similar_positions": 38, "identity": "1.24%" }, { "cls_id": "homologset.agr.MGI:1333838", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P43357-1", "uniprot_id": "MAGA3_HUMAN", "id": "P43357-1", "name": "Melanoma-associated antigen 3", "aln": "MPLEQRSQHCKPEEGLEARGEALGLVGAQAPATEEQEAASSSST---------------------LVEVTLGEVPAA-ESPDPPQSPQGASSLPTTMNYPLWSQSYEDSSNQEE--EGPSTFPD---LESEFQAALSRKVAELVHFLLLKYRAREPVTKAEMLGSVVGNWQYFFPVIFSKASSSLQLVFGIELMEVDPIGHLYI---FATCLGLSYDGLLGDNQIMPKAGLLIIVLAIIAREGDCAPEEKIWEELSVLEVFEGREDSILG-DPKKLLTQHFVQENYLEYR--QVPGSDPACYEFLWGPRALVETSYVKVLHHMVKISGGPHISYPPLHEWVLREGEE------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P43360-1", "uniprot_id": "MAGA6_HUMAN", "id": "P43360-1", "name": "Melanoma-associated antigen 6", "aln": "MPLEQRSQHCKPEEGLEARGEALGLVGAQAPATEEQEAASSSST---------------------LVEVTLGEVPAA-ESPDPPQSPQGASSLPTTMNYPLWSQSYEDSSNQEE--EGPSTFPD---LESEFQAALSRKVAKLVHFLLLKYRAREPVTKAEMLGSVVGNWQYFFPVIFSKASDSLQLVFGIELMEVDPIGHVYI---FATCLGLSYDGLLGDNQIMPKTGFLIIILAIIAKEGDCAPEEKIWEELSVLEVFEGREDSIFG-DPKKLLTQYFVQENYLEYR--QVPGSDPACYEFLWGPRALIETSYVKVLHHMVKISGGPRISYPLLHEWALREGEE------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P43365-1", "uniprot_id": "MAGAC_HUMAN", "id": "P43365-1", "name": "Melanoma-associated antigen 12", "aln": "MPLEQRSQHCKPEEGLEAQGEALGLVGAQAPATEEQETASSSST---------------------LVEVTLREVPAA-ESPSPPHSPQGASTLPTTINYTLWSQSDEGSSNEEQ--EGPSTFPD---LETSFQVALSRKMAELVHFLLLKYRAREPFTKAEMLGSVIRNFQDFFPVIFSKASEYLQLVFGIEVVEVVRIGHLYI---LVTCLGLSYDGLLGDNQIVPKTGLLIIVLAIIAKEGDCAPEEKIWEELSVLEASDGREDSVFA-HPRKLLTQDLVQENYLEYR--QVPGSDPACYEFLWGPRALVETSYVKVLHHLLKISGGPHISYPPLHEWAFREGEE------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P43356-1", "uniprot_id": "MAGA2_HUMAN", "id": "P43356-1", "name": "Melanoma-associated antigen 2", "aln": "MPLEQRSQHCKPEEGLEARGEALGLVGAQAPATEEQQTASSSST---------------------LVEVTLGEVPAA-DSPSPPHSPQGASSFSTTINYTLWRQSDEGSSNQEE--EGPRMFPD---LESEFQAAISRKMVELVHFLLLKYRAREPVTKAEMLESVLRNCQDFFPVIFSKASEYLQLVFGIEVVEVVPISHLYI---LVTCLGLSYDGLLGDNQVMPKTGLLIIVLAIIAIEGDCAPEEKIWEELSMLEVFEGREDSVFA-HPRKLLMQDLVQENYLEYR--QVPGSDPACYEFLWGPRALIETSYVKVLHHTLKIGGEPHISYPPLHERALREGEE------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P43358-1", "uniprot_id": "MAGA4_HUMAN", "id": "P43358-1", "name": "Melanoma-associated antigen 4", "aln": "MSSEQKSQHCKPEEGVEAQEEALGLVGAQAPTTEEQEAAVSSSSP--------------------LVPGTLEEVPAA-ESAGPPQSPQGASALPTTISFTCWRQPNEGSSSQEE--EGPSTSPD---AESLFREALSNKVDELAHFLLRKYRAKELVTKAEMLERVIKNYKRCFPVIFGKASESLKMIFGIDVKEVDPASNTYT---LVTCLGLSYDGLLGNNQIFPKTGLLIIVLGTIAMEGDSASEEEIWEELGVMGVYDGREHTVYG-EPRKLLTQDWVQENYLEYR--QVPGSNPARYEFLWGPRALAETSYVKVLEHVVRVNARVRIAYPSLREAALLEEEEGV----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P43361-1", "uniprot_id": "MAGA8_HUMAN", "id": "P43361-1", "name": "Melanoma-associated antigen 8", "aln": "MLLGQKSQRYKAEEGLQAQGEAPGLMDVQIPTAEEQKAASSSST---------------------LIMGTLEEVTDS-GSPSPPQSPEGASSSLTVTDSTLWSQSDEGSSSNEE--EGPSTSPDPAHLESLFREALDEKVAELVRFLLRKYQIKEPVTKAEMLESVIKNYKNHFPDIFSKASECMQVIFGIDVKEVDPAGHSYI---LVTCLGLSYDGLLGDDQSTPKTGLLIIVLGMILMEGSRAPEEAIWEALSVMGLYDGREHSVYW-KLRKLLTQEWVQENYLEYR--QAPGSDPVRYEFLWGPRALAETSYVKVLEHVVRVNARVRISYPSLHEEALGEEKGV-----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P43362-1", "uniprot_id": "MAGA9_HUMAN", "id": "P43362-1", "name": "Melanoma-associated antigen 9", "aln": "MSLEQRSPHCKPDEDLEAQGEDLGLMGAQEPTGEEEETTSSSDS-------------------------KEEEVSAA-GSSSPPQSPQGGASSSISVYYTLWSQFDEGSSSQEE--EEPSSSVDPAQLEFMFQEALKLKVAELVHFLLHKYRVKEPVTKAEMLESVIKNYKRYFPVIFGKASEFMQVIFGTDVKEVDPAGHSYI---LVTALGLSCDSMLGDGHSMPKAALLIIVLGVILTKDNCAPEEVIWEALSVMGVYVGKEHMFYG-EPRKLLTQDWVQENYLEYR--QVPGSDPAHYEFLWGSKAHAETSYEKVINYLVMLNAREPICYPSLYEEVLGEEQEGV----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P43363-1", "uniprot_id": "MAGAA_HUMAN", "id": "P43363-1", "name": "Melanoma-associated antigen 10", "aln": "MPRAPKRQRCMPEEDLQSQSETQGLEGAQAPLAVEEDASSSTSTSSSFPSSFPSSSSSSSSSCYPLIPSTPEEVSADDETPNPPQSAQIACSSPSVVASLPLDQSDEGSSSQKE--ESPSTLQVLPDSESLPRSEIDEKVTDLVQFLLFKYQMKEPITKAEILESVIRNYEDHFPLLFSEASECMLLVFGIDVKEVDPTGHSFV---LVTSLGLTYDGMLSDVQSMPKTGILILILSIVFIEGYCTPEEVIWEALNMMGLYDGMEHLIYG-EPRKLLTQDWVQENYLEYR--QVPGSDPARYEFLWGPRAHAEIRKMSLLKFLAKVNGSDPRSFPLWYEEALKDEEERAQDRIATTDDTTAMASASSSATGSFSYPE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZW04-1", "uniprot_id": "D3ZW04_RAT", "id": "D3ZW04-1", "name": "", "aln": "MDDAHNIQYSNLQDNAQAEQELDNAQATMAAAEEEEATSTS------------------------------KAEYGS-GIPSPLQSPERACSPSVALASIPVGPSEEASIRQLEALEDP---------LYLLHNAQNVKVYDLVDFLLFKYQTKAFTTKAEMLETIGREYDEYYPLIFSEASECMKLVFGLDIVEVDPSVHSYV---LVTALGITYDGMLTDVQGMPKTGVLIVVLGVIFMKGNYVSEDIIWEMLNNIGLCGGMDPYIHR-DPRKLISEEFVQEGYLEYR--QVPNSDPPSHVFLWGPRAFAETTKLKVLQFFASITKTHPRAYPEKYAEALRDEIDRVEAWIFQQMLRHL----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O89009-1", "uniprot_id": "O89009_MOUSE", "id": "O89009-1", "name": "", "aln": "MADFHNTQYCNLQESAQAQQELDNDQETMETSEEEEDTTTS------------------------------NKVYGS-GIPSPPQSPQRAYSPCVALASIPDSPSEEASIKGSEGLEDP---------LYLLHNAQNTKVYDLVDFLVLKYQMKAFTTKAEMLESIGREYEEYYPLIFSEASECLKMVFGLDMVEIDPSVHSYI---LVTALGITYDGMMTDVQGMPKTGILIAVLSVIFMKGNYVSEEIIWEMLNNIGLYGGRNPYIHK-DPRKLISEEFVQEGYLEYR--QVPNSDPPSYGFLWGPRAFAETSKMKVLQFFASINKTHPRAYPEKYAEALQDEIDRTKAWILNRCSNSSDLLTF-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9I7L4-1", "uniprot_id": "Q9I7L4_DROME", "id": "Q9I7L4-1", "name": "", "aln": "------------------------------------------------------------------------------------------------MASTSRAARSQNAIPSQE--------------AQQPVDVVDAKVRAILNYILDHTAQKIPIKDKDLIAVAGD--KSELKKRLPLVTNLLAETFGIILTPLDATTKTFI---CTAEEPVASIHELTPAQ-RPQFTLLYIILMYIFLRGNRIEDSKLYVMLEMLNIYPDEEHGYFGPNLRKQIEETFVKQQYLKRERSQLSAYDDSKTFFLWGPRAKAEFTFEQMVQFASKLLNQHPKVFGHHLSMAQEGVNAE-----------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q05541-1", "uniprot_id": "NSE3_YEAST", "id": "Q05541-1", "name": "Non-structural maintenance of chromosome element 3", "aln": "MSSIDNDSDVDLTEDLAVAKIVKENPVARKMVRYILSRGESQNS---------------------------------IITRNKLQSVIHEAAREENIAKPSFSKMFMDINAILY--------------NVYGFELQGLPSKNNMNAGGNGSNSNTNKSMPEPLGHRAQKFILLNNVPHSKNFDDFKILQSAHTYEELIVTGEYIGDDIASGTSNTLESKLSTDRDLVYKGVLSVILCIVFFSKNNILHQELIKFLETFGIPSDGSKIAILNITIEDLIKSLEKREYIVRLE-EKSDTDGEVISYRIGRRTQAELGLESLEKLVQEIMGLEKEQTKSLHDDIIKSIGDSYSI--------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : : . : . : .: : : : .* :* : .. : * : . . : : : :. *: : . : : * :: * .: . : ", "identical_positions": 6, "similar_positions": 38, "identity": "1.59%" }, { "cls_id": "homologset.agr.MGI:1333839", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P43357-1", "uniprot_id": "MAGA3_HUMAN", "id": "P43357-1", "name": "Melanoma-associated antigen 3", "aln": "MPLEQRSQHCKPEEGLEARGEALGLVGAQAPATEEQEAASSSST---------------------LVEVTLGEVPAA-ESPDPPQSPQGASSLPTTMNYPLWSQSYEDSSNQEEEGPSTFPD---LESEFQAALSRKVAELVHFLLLKYRAREPVTKA-----EMLGSVVGNWQYFFPVIFSKASSSLQLVFGIELMEVDPIGHLYI---FATCLGLSYDGLLGDNQIMPKAGLLIIVLAIIAREGDCAPEEKIWEELSVLEVFEGREDSILG-DPKKLLTQHFVQENYLEYR--QVPGSDPACYEFLWGPRALVETSYVKVLHHMVKISGGPHISYPPLHEWVLREGEE------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P43360-1", "uniprot_id": "MAGA6_HUMAN", "id": "P43360-1", "name": "Melanoma-associated antigen 6", "aln": "MPLEQRSQHCKPEEGLEARGEALGLVGAQAPATEEQEAASSSST---------------------LVEVTLGEVPAA-ESPDPPQSPQGASSLPTTMNYPLWSQSYEDSSNQEEEGPSTFPD---LESEFQAALSRKVAKLVHFLLLKYRAREPVTKA-----EMLGSVVGNWQYFFPVIFSKASDSLQLVFGIELMEVDPIGHVYI---FATCLGLSYDGLLGDNQIMPKTGFLIIILAIIAKEGDCAPEEKIWEELSVLEVFEGREDSIFG-DPKKLLTQYFVQENYLEYR--QVPGSDPACYEFLWGPRALIETSYVKVLHHMVKISGGPRISYPLLHEWALREGEE------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P43365-1", "uniprot_id": "MAGAC_HUMAN", "id": "P43365-1", "name": "Melanoma-associated antigen 12", "aln": "MPLEQRSQHCKPEEGLEAQGEALGLVGAQAPATEEQETASSSST---------------------LVEVTLREVPAA-ESPSPPHSPQGASTLPTTINYTLWSQSDEGSSNEEQEGPSTFPD---LETSFQVALSRKMAELVHFLLLKYRAREPFTKA-----EMLGSVIRNFQDFFPVIFSKASEYLQLVFGIEVVEVVRIGHLYI---LVTCLGLSYDGLLGDNQIVPKTGLLIIVLAIIAKEGDCAPEEKIWEELSVLEASDGREDSVFA-HPRKLLTQDLVQENYLEYR--QVPGSDPACYEFLWGPRALVETSYVKVLHHLLKISGGPHISYPPLHEWAFREGEE------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P43356-1", "uniprot_id": "MAGA2_HUMAN", "id": "P43356-1", "name": "Melanoma-associated antigen 2", "aln": "MPLEQRSQHCKPEEGLEARGEALGLVGAQAPATEEQQTASSSST---------------------LVEVTLGEVPAA-DSPSPPHSPQGASSFSTTINYTLWRQSDEGSSNQEEEGPRMFPD---LESEFQAAISRKMVELVHFLLLKYRAREPVTKA-----EMLESVLRNCQDFFPVIFSKASEYLQLVFGIEVVEVVPISHLYI---LVTCLGLSYDGLLGDNQVMPKTGLLIIVLAIIAIEGDCAPEEKIWEELSMLEVFEGREDSVFA-HPRKLLMQDLVQENYLEYR--QVPGSDPACYEFLWGPRALIETSYVKVLHHTLKIGGEPHISYPPLHERALREGEE------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P43358-1", "uniprot_id": "MAGA4_HUMAN", "id": "P43358-1", "name": "Melanoma-associated antigen 4", "aln": "MSSEQKSQHCKPEEGVEAQEEALGLVGAQAPTTEEQEAAVSSSSP--------------------LVPGTLEEVPAA-ESAGPPQSPQGASALPTTISFTCWRQPNEGSSSQEEEGPSTSPD---AESLFREALSNKVDELAHFLLRKYRAKELVTKA-----EMLERVIKNYKRCFPVIFGKASESLKMIFGIDVKEVDPASNTYT---LVTCLGLSYDGLLGNNQIFPKTGLLIIVLGTIAMEGDSASEEEIWEELGVMGVYDGREHTVYG-EPRKLLTQDWVQENYLEYR--QVPGSNPARYEFLWGPRALAETSYVKVLEHVVRVNARVRIAYPSLREAALLEEEEGV----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P43361-1", "uniprot_id": "MAGA8_HUMAN", "id": "P43361-1", "name": "Melanoma-associated antigen 8", "aln": "MLLGQKSQRYKAEEGLQAQGEAPGLMDVQIPTAEEQKAASSSST---------------------LIMGTLEEVTDS-GSPSPPQSPEGASSSLTVTDSTLWSQSDEGSSSNEEEGPSTSPDPAHLESLFREALDEKVAELVRFLLRKYQIKEPVTKA-----EMLESVIKNYKNHFPDIFSKASECMQVIFGIDVKEVDPAGHSYI---LVTCLGLSYDGLLGDDQSTPKTGLLIIVLGMILMEGSRAPEEAIWEALSVMGLYDGREHSVYW-KLRKLLTQEWVQENYLEYR--QAPGSDPVRYEFLWGPRALAETSYVKVLEHVVRVNARVRISYPSLHEEALGEEKGV-----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P43362-1", "uniprot_id": "MAGA9_HUMAN", "id": "P43362-1", "name": "Melanoma-associated antigen 9", "aln": "MSLEQRSPHCKPDEDLEAQGEDLGLMGAQEPTGEEEETTSSSDS-------------------------KEEEVSAA-GSSSPPQSPQGGASSSISVYYTLWSQFDEGSSSQEEEEPSSSVDPAQLEFMFQEALKLKVAELVHFLLHKYRVKEPVTKA-----EMLESVIKNYKRYFPVIFGKASEFMQVIFGTDVKEVDPAGHSYI---LVTALGLSCDSMLGDGHSMPKAALLIIVLGVILTKDNCAPEEVIWEALSVMGVYVGKEHMFYG-EPRKLLTQDWVQENYLEYR--QVPGSDPAHYEFLWGSKAHAETSYEKVINYLVMLNAREPICYPSLYEEVLGEEQEGV----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P43363-1", "uniprot_id": "MAGAA_HUMAN", "id": "P43363-1", "name": "Melanoma-associated antigen 10", "aln": "MPRAPKRQRCMPEEDLQSQSETQGLEGAQAPLAVEEDASSSTSTSSSFPSSFPSSSSSSSSSCYPLIPSTPEEVSADDETPNPPQSAQIACSSPSVVASLPLDQSDEGSSSQKEESPSTLQVLPDSESLPRSEIDEKVTDLVQFLLFKYQMKEPITKA-----EILESVIRNYEDHFPLLFSEASECMLLVFGIDVKEVDPTGHSFV---LVTSLGLTYDGMLSDVQSMPKTGILILILSIVFIEGYCTPEEVIWEALNMMGLYDGMEHLIYG-EPRKLLTQDWVQENYLEYR--QVPGSDPARYEFLWGPRAHAEIRKMSLLKFLAKVNGSDPRSFPLWYEEALKDEEERAQDRIATTDDTTAMASASSSATGSFSYPE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F2Z493-1", "uniprot_id": "F2Z493_MOUSE", "id": "F2Z493-1", "name": "", "aln": "MENPDNTHYCSLQGSARSQRE-LDNVQATIAVVDEEEATPTSKK-----------------------------VYSS-GIPSPPQSPQRASSPLVILASVPEGPSEEASTNQVEEQED-------PLCMLYNAQNIKLYELATFLFFKYQMKAFTTKA-----EMLESIGREYEEYYPLIFSEASECFKLVSGIGMIEVDPFVQSYI---LVPALGLTYDGMLTDVQSKPKTGILIVVLGAIFTQGNCVSEEIIWKMLNNIGLYGGRHLYIHQ-DPRKFISEEFVQEGYLEYR--QVPNSDPPSYEFLWDPRAFAETTKMKVLEIFASITMTDPRAYTEKYAEALRDETERAQARIIQQIVLQL----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9I7L4-1", "uniprot_id": "Q9I7L4_DROME", "id": "Q9I7L4-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------MASTSRAARSQNAIPSQEAQQPVD-------------VVDAKVRAILNYILDHTAQKIPIKDK-----DLIAVAGD--KSELKKRLPLVTNLLAETFGIILTPLDATTKTFI---CTAEEPVASIHELTPAQ-RPQFTLLYIILMYIFLRGNRIEDSKLYVMLEMLNIYPDEEHGYFGPNLRKQIEETFVKQQYLKRERSQLSAYDDSKTFFLWGPRAKAEFTFEQMVQFASKLLNQHPKVFGHHLSMAQEGVNAE-----------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q05541-1", "uniprot_id": "NSE3_YEAST", "id": "Q05541-1", "name": "Non-structural maintenance of chromosome element 3", "aln": "MSSIDNDSDVDLTEDLAVAKIVKENPVARKMVR--------------------------------------------------YILSRGESQNSIITRNKLQSVIHEAAREENIAKPSFSKMFMDINAILYNVYGFELQGLPSKNNMNAGGNGSNSNTNKSMPEPLGHRAQKFILLNNVPHSKNFDDFKILQSAHTYEELIVTGEYIGDDIASGTSNTLESKLSTDRDLVYKGVLSVILCIVFFSKNNILHQELIKFLETFGIPSDGSKIAILNITIEDLIKSLEKREYIVRLE-EKSDTDGEVISYRIGRRTQAELGLESLEKLVQEIMGLEKEQTKSLHDDIIKSIGDSYSI--------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .: :: : : . .. : : . : . : .. : * : .* ::* : .. : * : . : : : :. *: : . : : . :: * .: . : ", "identical_positions": 6, "similar_positions": 46, "identity": "1.58%" }, { "cls_id": "homologset.agr.MGI:1333842", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O89100-1", "uniprot_id": "GRAP2_MOUSE", "id": "O89100-1", "name": "GRB2-related adaptor protein 2", "aln": "MEATAKFDFMASGEDELSFRTGDILKILSNQEEWLKAELGSQEGYVPKNFIDIEFPEWFHEGLSRHQAENLLMGKDIGFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDTKGNYFLWTEKFPSLNKLVDYYRTTSISKQKQVFLRDGTQ-DQGHRGNSLDRRSQGGPHPSGTVGEEIRPSVNRKLSDHLPLGPQQFHPHQQPSPQFTPGPQPPQQ---QRYLQH--FHQDRRGGSLDINDGHCG--LGSEVNATLMHRRHTDPVQLQAAGRVRWARALYDFEALEEDELGFRSGEVVEVLDSSNPSWWTGRLHNKLGLFPANYVAPMMR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75791-1", "uniprot_id": "GRAP2_HUMAN", "id": "O75791-1", "name": "GRB2-related adapter protein 2", "aln": "MEAVAKFDFTASGEDELSFHTGDVLKILSNQEEWFKAELGSQEGYVPKNFIDIQFPKWFHEGLSRHQAENLLMGKEVGFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDNKGNYFLWTEKFPSLNKLVDYYRTNSISRQKQIFLRDRTREDQGHRGNSLDRRSQGGPHLSGAVGEEIRPSMNRKLSDHPPTLPLQQHQHQPQPPQYAPAPQQLQQPPQQRYLQHHHFHQERRGGSLDINDGHCGTGLGSEMNAALMHRRHTDPVQLQAAGRVRWARALYDFEALEDDELGFHSGEVVEVLDSSNPSWWTGRLHNKLGLFPANYVAPMTR", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***.***** *********:***:**********:******************:**:******************::*********************************.***********************.***:***:**** *: ****************** **:********:******* * * * * ** .**::*.** ** ****** ***:************** ****:**:*******************************:*****:*********************************** *", "identical_positions": 284, "similar_positions": 24, "identity": "86.06%" }, { "cls_id": "homologset.agr.MGI:1333843", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K211-1", "uniprot_id": "COPT1_MOUSE", "id": "Q8K211-1", "name": "High affinity copper uptake protein 1", "aln": "-----MNHMGMNHMEMHHHMGMNHTD---------------------DNITMPP-HHHPTTSASHSHGGGDS-----MMMMPMTFYFDFKNVNLLFSGLVINTPGEMAGAFVAVFLLAMFYEGLKIAREGLLRKS------------------QVSIRYN------------------------SMPVPGPNG----------TILMETHKTVGQQ------------MLSFPHLLQTVLHIIQVVISYFLMLIFMTYNGYLCIAVAAGAGTG-YFLFSWKKAVVVDITEHCH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9JK41-1", "uniprot_id": "COPT1_RAT", "id": "Q9JK41-1", "name": "High affinity copper uptake protein 1", "aln": "--------MRMNHMEMHH-MGMNHTD---------------------DNITMPP-HQHPTTSASHSH----------EMMMPMTFYFGFKNVDLLFSSLVINTPGEMAGAFVAVFLLAMFYEGLKIAREGLLRKS------------------QVSIRYN------------------------SMPVPGPNG----------TILMETHKTVGQQ------------MLSFPHLLQTVLHIIQVVISYFLMLIFMTYNGYLCIAVAAGAGTG-YFLFSWKKAVVVDITEHCH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O15431-1", "uniprot_id": "COPT1_HUMAN", "id": "O15431-1", "name": "High affinity copper uptake protein 1", "aln": "-------------MDHSHHMGMSYMD---------------------SNSTMQPSHHHPTTSASHSHGGGDSS----MMMMPMTFYFGFKNVELLFSGLVINTAGEMAGAFVAVFLLAMFYEGLKIARESLLRKS------------------QVSIRYN------------------------SMPVPGPNG----------TILMETHKTVGQQ------------MLSFPHLLQTVLHIIQVVISYFLMLIFMTYNGYLCIAVAAGAGTG-YFLFSWKKAVVVDITEHCH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QKH1-1", "uniprot_id": "F1QKH1_DANRE", "id": "F1QKH1-1", "name": "Copper transport protein", "aln": "-------------MDMSH--SHHHVE---------------------ETTMPSPASDDHGGHLTTSGNGHGDH----MMMMQMTFYFGYKNVELLFAGLVINTPGEMAGACIGVFLLAVLYEGLKIGREVLLRRN------------------QVNVRYN------------------------SMPVPGSDG----------TVLMETHKTVGQR------------MLSMAHFLQTLLHIIQVVVSYFLMLVFMTYNGYLCIAVAAGAGLG-YFLFSWKKAVVVDITEHCH", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9NE97-1", "uniprot_id": "M9NE97_DROME", "id": "M9NE97-1", "name": "Copper transport protein", "aln": "MDHAHHSAPGVDHSMHHDHVGMHHDHSGIPAATASPMDAASMFDLIPDTSDLQASHAGHAAHGAHNHGGGSGTGM--EHMMPMAFHFGYN-ETILFSWWHIETVAGLIGSMIAIFLLALMYEGLKYYREYLFWKT------------------YNLLEYRPVTGPQRN------------PEAPRIPSPAAAAP---------SPVQYVGEVVHKQPP---------SMLSINHLLQTLLHVLQVTLSFLLMLIFMTYNVWLCLMVVLGAAVG-YFLFCWKKSVIVDVTEHCH", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VA22-1", "uniprot_id": "Q9VA22_DROME", "id": "Q9VA22-1", "name": "Copper transport protein", "aln": "---MDHHGVDASEGHVHHHASHGSPEPVPPSSG--------------HEGHHSPEMNHHGNHGEHTKHGHHEGGA--HDMSMAMFFHTGDSETILFKFWRTESAMALTLSCLLIFMVAVLYEALKFFREWLFSWDRKRLAGGRDQYNRPRRYREANYNYNQPTYPPRTNQQSGTQVYAYRPRSPSMPPLQPPGRSSPQAQSSLILTQHTHHHVQENTPPAGRTTKLKVFCSGMHILQTFLHVLQVLISFLLMLVFMTFNVWLCVAVLLGAGVG-YYIFCAFR---TNVQEHCN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38865-1", "uniprot_id": "CTR2_YEAST", "id": "P38865-1", "name": "Copper transport protein CTR2", "aln": "-MDDKKTWSTVTLRTFNQLVTSSLIG---------------------YSKKMDSMNHKMEGNAGHDHSDMHMGDGDDTCSMNMLFSWSYKNTCVVFEWWHIKTLPGLILSCLAIFGLAYLYEYLKYCVHKRQLSQR--------------------------------------------------------------------VLLPNRSLTKIN--------------QADKVSNSILYGLQVGFSFMLMLVFMTYNGWLMLAVVCGAIWGNYSWCTSYSPEIDDSSLACH", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . * . ::* :: : : : :* :* :** ** . . . . :. ::.*: :** .*::***:***:* :* : * ** * * : *:", "identical_positions": 26, "similar_positions": 33, "identity": "8.87%" }, { "cls_id": "homologset.agr.MGI:1333844", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4AAE7-1", "uniprot_id": "D4AAE7_RAT", "id": "D4AAE7-1", "name": "Copper transport protein", "aln": "-----------------MPMHFIF-SDEAVLLFDFWRVHSPTGMALSVLVVLLLAVLYEG-----IKVGKAKLLHKTLESLPTTTSQ------------------------QLILEPDQDSTGSRSTSDNRTRLRWF-------------------------------------------------LCYFGQSLVHVIQVVIGYFVMLAVMSYNTWIFLGVVLGSAVG-YYLAYPLL-----------------HMT------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CPU9-1", "uniprot_id": "COPT2_MOUSE", "id": "Q9CPU9-1", "name": "Protein SLC31A2", "aln": "-----------------MPMHFIF-SDEAVLLFDFWRVHSPTGMALSVLVVLLLAVLYEG-----IKVGKAKLLHKTLESLPATNSQ------------------------QFILGPDQDSTGSRSTSDNRTRLRWF-------------------------------------------------LCYFGQSLVHVIQVVIGYFVMLAVMSYNTWIFLGVVLGSAVG-YYLAYPLL-----------------NMT------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15432-1", "uniprot_id": "COPT2_HUMAN", "id": "O15432-1", "name": "Protein SLC31A2", "aln": "-----------------MAMHFIF-SDTAVLLFDFWSVHSPAGMALSVLVLLLLAVLYEG-----IKVGKAKLLNQVLVNLPTSISQ------------------------QTIAETDGDSAGSDSFPVGRTHHRWY-------------------------------------------------LCHFGQSLIHVIQVVIGYFIMLAVMSYNTWIFLGVVLGSAVG-YYLAYPLL-----------------STA------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B4K8-1", "uniprot_id": "A0A8M3B4K8_DANRE", "id": "A0A8M3B4K8-1", "name": "Copper transport protein", "aln": "-----------------MHMYFEG-SSNVTLLFNFWNVHGPAGMVLSVFVVLLLTVVYELLKVWKITVGKQKSSPNTSPSTAMSFSQNKQSCFATVIKCQEGSSSLANSPSEVSLTPTENTDNAADSSTAAKRRRWI-------------------------------------------------LHCL-QTAIHIVQVTLGYMLMLCVMSYNIWIFLGVITGSVLG-YFVAFPLL-----------------NHT------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VHS6-1", "uniprot_id": "Q9VHS6_DROME", "id": "Q9VHS6-1", "name": "Copper transport protein", "aln": "MDHGSDDSTSTAKS-CPMIMVFHA-GHCERILWRGWVASTVTEFVLSALAIFLVSFLYEALKFLRQQLAR-REARRASEQLAAEQRR------------------------KNEAPAAGGCCSEAPLAEPREQTYWQRLFA---------------------------------------------SSHIVQSLLNLLQIVISYLLMLIFMTFNYWLCLAVILGLGLGYFFFGWNKK-----------------NPDESECCP", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06686-1", "uniprot_id": "CTR3_YEAST", "id": "Q06686-1", "name": "Copper transport protein CTR3", "aln": "MNMGGSSSTAAKKATCKISMLWNWYTIDTCFIARSWRNDTKGKFAGSCIGCFALVVVAQWLTRFSRQFDVELLKRQKIKHLASYSPEE----------------------YVVKCGEEDAKSDIEELQGFYNEPSWKTTLISLQKSFIYSFYVWGPRRLNEPEDDLLKKVLSCCTLITPVDLYPTFLDHMIRVTIFVLQWGLSYIIMLLFMYYNGYIIISCLIGAIVGRFIFCYEPLGSLGANGSAQGTVSYDKESDDRKCCL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * : :: * :. * : : : .: : . . . . . . * : : : ::* :.*::** .* :* :: :. : * :* : . : ", "identical_positions": 12, "similar_positions": 38, "identity": "4.56%" }, { "cls_id": "homologset.agr.MGI:1333849", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P0C643-1", "uniprot_id": "GRP2_RAT", "id": "P0C643-1", "name": "RAS guanyl-releasing protein 2", "aln": "-------------MASTLDLDKGCTVEEL----LRGCIEAFDDSGKVRDPQLVRMFLMMHPWYIPSSQLASKLLHFYQQSRKDNSNSLQVK-----------------TCHLVRYWVSAFPAEFDLNPELAEQIKELKALLD-----------------------QEGNRRHSSLIDIESVPTYKWKRQVTQRNPVEQKKRK-----------------MSLLFDHLEPMELAEHLT----YLEYRSFCKILFQDYHS--FVTHGCTVDNPVLERFISLFNS---VSQWVQLMILS------------------KPTATQRALVITHFVHVAEKLLQLQNFNTLMAVVGGLSHSSISRLKETHSHVSPDTIKLWEGLTELVTATGNYSNYRRR---------------------------------------LAACVGFRFPILGVHLKDLVALQLALP-DWLDPGRTRLNGAK---------------------------MRQLFSILEELAMVTSLRPPVQANPDLLSLLTVSLDQYQTEDE-----------------------------------------------------LYQLSLQREPRSKSSPTSPTSCTPPPRPPVLEEWTSVAKPKLDQALVAEHIEKMVESVFRNFDVDGD--------------------------------GHISQEEFQIIRGN--------FPYLSAFGDLDQNQDGCISREEMISYFLRSSSVLG-------GRMGFVHNLQESNSLRPVACRHCKALILGIYKQG---------LKCRACGVNCHKQCKDRLSVECRRRAQSVSLEGSAPSPSPTHT-HHRAFSFSLPRP---------GRRSSRPPEIREEEVQTVEDGVFDIHL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QUG9-1", "uniprot_id": "GRP2_MOUSE", "id": "Q9QUG9-1", "name": "RAS guanyl-releasing protein 2", "aln": "-------------MTSTLDLDKGCTVEEL----LRGCIEAFDDSGKVRDPQLVRMFLMMHPWYIPSSQLASKLLHFYQQSRKDNSNSLQMK-----------------TCHLVRYWISAFPAEFDLNPELAEQIKELKALLD-----------------------QEGNRRHSSLIDIESVPTYKWKRQVTQRNPVEQKKRK-----------------MSLLFDHLEPMELAEHLT----YLEYRSFCKILFQDYHS--FVTHGCTVDNPVLERFISLFNS---VSQWVQLMILS------------------KPTATQRALVITHFVHVAERLLQLQNFNTLMAVVGGLSHSSISRLKETHSHVSPDTIKLWEGLTELVTATGNYSNYRRR---------------------------------------LAACVGFRFPILGVHLKDLVALQLALP-DWLDPGRTRLNGAK---------------------------MRQLFCILEELAMVTSLRPPVQANPDLLSLLTVSLDQYQTEDE-----------------------------------------------------LYQLSLQREPRSKSSPTSPTSCTPPPRPPVLEEWTSVAKPKLDQALVAEHIEKMVESVFRNFDVDGD--------------------------------GHISQEEFQIIRGN--------FPYLSAFGDLDQNQDGCISREEMISYFLRSSSVLG-------GRMGFVHNFQESNSLRPVACRHCKALILGIYKQG---------LKCRACGVNCHKQCKERLSVECRRRAQSVSLEGSAPSPSPTHT-HHRAFSFSLPRP---------GRRSSRPPEIREEEVQSVEDGVFDIHL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7LDG7-1", "uniprot_id": "GRP2_HUMAN", "id": "Q7LDG7-1", "name": "RAS guanyl-releasing protein 2", "aln": "-------------MAGTLDLDKGCTVEEL----LRGCIEAFDDSGKVRDPQLVRMFLMMHPWYIPSSQLAAKLLHIYQQSRKDNSNSLQVK-----------------TCHLVRYWISAFPAEFDLNPELAEQIKELKALLD-----------------------QEGNRRHSSLIDIDSVPTYKWKRQVTQRNPVGQKKRK-----------------MSLLFDHLEPMELAEHLT----YLEYRSFCKILFQDYHS--FVTHGCTVDNPVLERFISLFNS---VSQWVQLMILS------------------KPTAPQRALVITHFVHVAEKLLQLQNFNTLMAVVGGLSHSSISRLKETHSHVSPETIKLWEGLTELVTATGNYGNYRRR---------------------------------------LAACVGFRFPILGVHLKDLVALQLALP-DWLDPARTRLNGAK---------------------------MKQLFSILEELAMVTSLRPPVQANPDLLSLLTVSLDQYQTEDE-----------------------------------------------------LYQLSLQREPRSKSSPTSPTSCTPPPRPPVLEEWTSAAKPKLDQALVVEHIEKMVESVFRNFDVDGD--------------------------------GHISQEEFQIIRGN--------FPYLSAFGDLDQNQDGCISREEMVSYFLRSSSVLG-------GRMGFVHNFQESNSLRPVACRHCKALILGIYKQG---------LKCRACGVNCHKQCKDRLSVECRRRAQSVSLEGSAPSPSPMHSHHHRAFSFSLPRP---------GRRGSRPPEIREEEVQTVEDGVFDIHL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7TAP0-1", "uniprot_id": "A0A8N7TAP0_DANRE", "id": "A0A8N7TAP0-1", "name": "", "aln": "--------------MESVSWDQPASVEEL----VEACIKAFDNEGVLKDPSLVRMFLTMHPWYLSSSDLAKKLLQKSQQ--QDCSANRQSQ-----------------ICHLVKYWISEFPAEFDLNPALAEQIRGLKERLE-----------------------QNGDVRRSLLIDIDSIPSYEWRRQLDET---VQKKRK-----------------TSLLFDHLDASTLAEHLT----YMEYKSFCKILFQDYHS--FVMHGCTVDNPILERFITLFNS---VSQWIQIMVLS------------------KPTAQQRATVISEFIKVAERLLQLQNFNTLMAVVGGLSNSSIARLKNTQALISSDTRKVFDGLVELVTSFGNYSRYRQR---------------------------------------FSECSGFRFPILGVHLKDLIAVHVALP-DWIDPEKTRVNLTK---------------------------TYQLYAILEELALIQSTPPNIEANTDLLNLLIVSLDQYHSEDD-----------------------------------------------------IYQLSLQREPRSIKLSTS----SSKSQSPLIEQWASSVKPKADPSIINKHIEKMVESVFQNYDTDGD--------------------------------GYISQEEFEIIRSN--------FPYLGKFDELDQNQDCKISREEMIEYFTKASSLQN-------CKMGFVHTFAETSSIKPSFCRHCSRLIWGFYNQR---------CKCKVCGVSCHKDCVSRLAIECRKRTQSVSVYNDVSSKA------TRSFSFPPPQS---------TETIAESPVICTDPLQDQDE-VFDVYL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P07866-1", "uniprot_id": "LTE1_YEAST", "id": "P07866-1", "name": "Guanine nucleotide exchange factor LTE1", "aln": "MEIFSQKDYYPTPSSNVISYESDCVSKPVNSADLPALIVHLSSPLEGVDYNASADFFLIYRNFITPQDLHDLLIYRFRWCIREITTNAAKAKRRRIGEVALVRTFVLLRHSILNYFVQDFLPNITLRLRLIEFLNDKHIEQYPKIISSCIINLKKNWVHCSKLVWENIELNEPDKLDFDAWLHYSLKDFTQLESLHKRGSRLSIYARQSFASPDFRNQSVLSLYKTSDVFRLPEKLQSSNSSKNQRSPSMLLFPDNTSNVYSKHRIAKEPSVDNESEDMSDSKQKISHLSKVTLVSTLMKGVDYPSSYAVDKIMPPTPAKKVEFILNSLYIPEDLNEQSGTLQGTSTTSSLDNNSNSNSRSNTSSMSVLHRSAIGLLAKWMKNHNRHDSSNDKKFMSAIKPANQKPEMDAFVKYVVSISSLNRKSSKEEEEEFLNSDSSKFDILSARTIDEVESLLHLQNQLIEKVQTHSNNNRGPTVNVDCERREHIHDIKILQQNSFKPSNDNFSAMDNLDLYQTVSSIAQSVISLTNTLNKQLQNNESNMQPSPSYDALQRRKVKSLTTAYYNKMHGSYSAESMRLFDKDNSSSRTDENGPQRLLFHETDKTNSEAITNMTPRRKNHSQSQKSMTSSPLKNVLPDLKESSPLNDSREDTESITYSYDSELSSSSPPRDTVTKKSRKVRNIVNNTDSPTLKTKTGFLNLREFTFEDTKSLDEKKSTIDGLEKNYDNKENQESEYESTKKLDNSLDASSEANNYDITTRKKHSSCNHKIKQAVVRPASGRISISRVQSIAITPTKELSIVDPEQNKSNSVIEEISEIEPLNLEYNKKSALYSDTSSTVISISTSKLFESAQNSPLKQTQNPQREFPNGTSVSETNRIRLSIAPTIESVVSDLNSITTGSTVETFETSRDLPVPHQRIINLREEYQRGNQDIISNTSSLHELKTIDLSDSNNDLESPSTHAKNNKYFFSPDDGSIDVASPMKNVEELKSKFLKNESETNSNISGSVLTMDDIDINDTSSARNTRRANSESAFTGSLNKKNLNEIANMLDDSINDDPITVALMKLEGTYEKIPEKPENTKSSDAIGIKTSKLADEVEMLNLNNLPSFQNSPAEKRKSLLIERRRQTIMNIPFTPDQSEKEGFTSSSPEKIDVSANVDVAVQAAQIQELIGQYRIHDSRLMISNNESHVPFILMYDSLSVAQQMTLIEKEILGEIDWKDLLDLKMKHEGPQVISWLQLLVRNETLSGIDLAISRFNLTVDWIISEILLTKSSKMKRNVIQRFIHVADHCRTFQNFNTLMEIILALSSSVVQKFTDAWRLIEPGDLLTWEELKKIPSLDRNYSTIRNLLNSVNPLVGCVPFIVVYLSDLSANAEKKDWILEDKVVNYNKFDTNVQIVKNFIQRVQWSKFYTFKVNHELLSKCVYISTLTQEEINELST", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. :. . : : : . * :.. * . *: :: ::...:* *: : :: : . ::.*::. * .:: *. * * :. : :: : ... :*::: *. : : .* *:. : *.*:* : :* . :** * * : * : : .: :. : :* :*: :: ::* **. ::. .* . : :.* * : .. :....*.:.* :. :.. : :* . *.: :. ..:. . : : . . :* **..: * : : * : :: :*: * : : :. :::* : : . :: .* . * .*:: .:: : ::: : : :..: . *. . .: .: .. . . *. . : :. .: .**: .:* : . *.:. .** : : : * : .:**: . : :. :** . : . : : ::* * . : .: : : .* . . . * :* .::: * ... : . . :. :.. * . :. * *: ", "identical_positions": 68, "similar_positions": 238, "identity": "4.74%" }, { "cls_id": "homologset.agr.MGI:1333850", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z2D7-1", "uniprot_id": "MBD4_MOUSE", "id": "Q9Z2D7-1", "name": "Methyl-CpG-binding domain protein 4", "aln": "-----MESPNLGD-NRVR----GESLVPDPPWDRCKEDIAVGLGGVGEDGKDLVIS--SERSSLLQEPTASTLSS-TTATEGHKPVPCGWERVVKQRLSGKTAGKFDVYFISPQGLKFRSKRSLANYLLKNGETFLKPEDFNFTVLPKGSINPGYKHQSLAALTSLQPNETDVSKQNLKTRSKWKTDVLPLPSGTSESPESSGLSNSNSACLLLREHRDIQDVDSEKRRKSKRKVTVLKGTASQKTKQKCRKSLLESTQRNRKRASVVQKVGADRELVPQESQLNRTLCPADACAR-ETVGLAGEEK--------SPSPGLDLCFIQVTSGTTNKFHSTEAAGEAN----REQTFLESEEIRSKGDRKG-EAHLHTGVLQDGSEMP-SCSQAKKHFT-SETFQEDSIPRTQVEKRKTSLYFSSKYNKEALSPPRRKSFKKWTPPRSPFNLVQEILFHDPWKLLIATIFLNRTSGKMAIPVLWEFLEKYPSAEVARAADWRDVSELLKPLGLYDLRAKTIIKFSDEYLTKQWRYPIELHGIGKYGNDSYRIFCVNEWKQVHPEDHKLNKYHDWLWENHEKLSLS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AH85-1", "uniprot_id": "A0A8I6AH85_RAT", "id": "A0A8I6AH85-1", "name": "Methyl-CpG-binding domain protein 4", "aln": "-----MESPSLGD-NNVPSVTAGKSLVSDPPWDRCKEDVAVGLGGVGEDGKDLVIS--SECGSLLQEPAASTLPSCTTVAECHKPVPCGWERVVKQRLSGKTAGRVDVYFISPQGSKFRSKRSLANYLLKTGETCLKPEDFDFTVLSKGGINPGYKHQSLSAPASQQPNEADISKLNLRTRSKWKTDVLPLPGGNSESPDSNSLSNSNSARLLLKEHKGIQDADSGKSRKPKIKVTVLKGIASQRTKQRCRKSPSDSTGRNRKRLCTVQKADTDSELVPQESRLHRTVCPADACAR-ATVSLVREAKGLGE----EKSPSSDLRFTQVTSSITNKLYSTEAAGEATREATREQTFLESEEIRSKGEEE--EAHLHIDILQSGSETP-SCSQAKKHLT-SETFREDSIPRTQVEKRKTSLYFSSKYNKEALSPPRRKAFKKWTPPRSPFNLVQETLFHDPWKLLISTIFLNRTSGKMAIPVLWEFLEKYPSAEVARTADWRDVSELLKPLGLYDLRAKTIIKFSDEYLTKPWRYPIELHGIGKYGNDSYRIFCVNEWKQVHPEDHKLNKYHDWLWENHEKLSLS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O95243-1", "uniprot_id": "MBD4_HUMAN", "id": "O95243-1", "name": "Methyl-CpG-binding domain protein 4", "aln": "MGTTGLESLSLGDRGAAPTVTSSERLVPDPPNDLRKEDVAMELERVGEDEEQMMIKRSSECNPLLQEPIASAQFGATAGTECRKSVPCGWERVVKQRLFGKTAGRFDVYFISPQGLKFRSKSSLANYLHKNGETSLKPEDFDFTVLSKRGIKSRYKDCSMAALTSHLQNQSNNSNWNLRTRSKCKKDVFMPPSSSSELQESRGLSNFTSTHLLLKEDEGVDDVNFRKVRKPKGKVTILKGIPIKKTKKGCRKSCSGFVQSDSKRESVCNKADAESEPVAQKSQLDRTVCISDAGACGETLSVTSEENSLVKKKERSLSSGSNFCSEQKTSGIINKFCSAKDSEHNEK---YEDTFLESEEIGTKVEVVERKEHLHTDILKRGSEMDNNCSPTRKDFTGEKIFQEDTIPRTQIERRKTSLYFSSKYNKEALSPPRRKAFKKWTPPRSPFNLVQETLFHDPWKLLIATIFLNRTSGKMAIPVLWKFLEKYPSAEVARTADWRDVSELLKPLGLYDLRAKTIVKFSDEYLTKQWKYPIELHGIGKYGNDSYRIFCVNEWKQVHPEDHKLNKYHDWLWENHEKLSLS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :** .*** . . .: **.*** * ***:*: * **** ::::*. ** ..***** **: . *: :* :*.************* *****:.********* ***** ****** *.*** ******:****.* .*:. **. *::* :* *::: *: **:**** *.**: *...** :* .*** .*: ***:*...::*.: * **.* ***:*** . ::**: **** . : ** .. :*..:: * *.*:*:*.**:* :** * *:.:. * : . *.. :: * **. **: *:: : . *:******** :* : : *** .:*: *** .** ::*.:* .: *:**:*****:*:**********************:**************** **********:*****************:************:***********************:********* *:***************************************************", "identical_positions": 346, "similar_positions": 117, "identity": "59.35%" }, { "cls_id": "homologset.agr.MGI:1333853", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZTA9-1", "uniprot_id": "D3ZTA9_RAT", "id": "D3ZTA9-1", "name": "Sulfotransferase", "aln": "MGQRLSGGRSCLDVPGRFLPQPPPPPPPVRRKLALLFAMLCIWLYMFLYSCAGSCTAAPGLLLLGSGSRATHAQPALITAPNETSPKMPFRAPPANSLVAGKDKTVGAGSQEEQSPEAPDSPSPISSFFSGAG-SKQLPQAIIIGVKKGGTRALLEFLRVHPDVRAVGAEPHFFDRSYHKGLAWYRDLMPRTLEGQITMEKTPSYFVTREAPARISAMSKDTKLIVVVRDPVTRAISDYTQTLSKRPDIPSFESLTFRNRSAGLIDTSWSAIQIGLYAKHLEPWLRHFPLGQMLFVSGERLVSDPAGELRRVQDFLGLKRIITDKHFYFNQTKGFPCLKKAEGSGKPHCLGKTKGRAHPTIAREVLRQLRDFYRPFNRKFYQMTGRDFGWD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QZS6-1", "uniprot_id": "HS3SB_MOUSE", "id": "Q9QZS6-1", "name": "Heparan sulfate glucosamine 3-O-sulfotransferase 3B1", "aln": "MGQRLSGGRSCLDVPGRFLPQPPPPPPPVRRKLALLFAMLCIWLYMFLYSCAGSCTAAPGLLLLGSGSRATHAQPALVTAPNETSPKMPFRAPPANSLAAGKDKTVGAGSQEEQSPEAPDSPSPISSFFSGAG-SKQLPQAIIIGVKKGGTRALLEFLRVHPDVRAVGAEPHFFDRSYHKGLAWYRDLMPRTLKGQITMEKTPSYFVTREAPARISAMSKDTKLIVVVRDPVTRAISDYTQTLSKRPDIPSFESLTFRNRSAGLIDTSWSAIQIGLYAKHLEPWLRHFPLGQMLFVSGERLVSDPAGELRRVQDFLGLKRIITDKHFYFNQTKGFPCLKKAEGSGKPHCLGKTKGRAHPTIAREVLRQLRDFYRPFNRKFYQMTGRDFGWD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y662-1", "uniprot_id": "HS3SB_HUMAN", "id": "Q9Y662-1", "name": "Heparan sulfate glucosamine 3-O-sulfotransferase 3B1", "aln": "MGQRLSGGRSCLDVPGRLLPQPPPPPPPVRRKLALLFAMLCVWLYMFLYSCAGSCAAAPGLLLLGSGSRAAHDPPALATAPDGTPPRLPFRAPPATPLASGKEMAEGAASPEEQSPEVPDSPSPISSFFSGSG-SKQLPQAIIIGVKKGGTRALLEFLRVHPDVRAVGAEPHFFDRSYDKGLAWYRDLMPRTLDGQITMEKTPSYFVTREAPARISAMSKDTKLIVVVRDPVTRAISDYTQTLSKRPDIPTFESLTFKNRTAGLIDTSWSAIQIGIYAKHLEHWLRHFPIRQMLFVSGERLISDPAGELGRVQDFLGLKRIITDKHFYFNKTKGFPCLKKAEGSSRPHCLGKTKGRTHPEIDREVVRRLREFYRPFNLKFYQMTGHDFGWD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NCQ3-1", "uniprot_id": "A0A8M1NCQ3_DANRE", "id": "A0A8M1NCQ3-1", "name": "Sulfotransferase", "aln": "-----------MEYSAHFHS-----AQPVKNKLFVFCIMLSLWVYM-LYCCVGYCSTTPTFMMDERSNRRALQRQDPEMLLKSQSRDLLNNDSDADSRGDGWEENKGDAAYDEDD-------SGIAGAVNGSE-SKKLPQAIIIGVKKGGTRALLEFLRLHPDIRAVGAEPHFFDRNYEKGLEWYRELMPKTLDGQLTMEKTPSYFVTKEVPGRIHAMSRDTKLIVVVRDPVTRAISDYTQTRSKKPDIPSFESLTFKNLSTNVIDTSWSAVQIGMYARHLERWLQFFPMSQLLFVSGERLISDPSGEMARVQHFLGLRREVTHKHFHFNPAKGFPCLKRPESNSKPHCLGKTKGRTHPNINPEVIQRLRDFYKPFNKKFYHMTGHDFGWD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VWJ7-1", "uniprot_id": "Q9VWJ7_DROME", "id": "Q9VWJ7-1", "name": "", "aln": "----MRDTAATSAQPAMIVMSIWCSSLSLSSRSLAIALVICVTLVYFSYSFNACLLASISRSLQQSNLR---NLLALTSSPRNETNNAANSSSSNSSSSRNSSSTTGAPPAQTVTSSLDGAPKYQLLRQQGLRPSRHLPDTLIIGVKKSGTRALLEFIRLHPDVRAAGSEVHFFDRHYQRGLRWYRHHMPYTIEGQITMEKTPSYFVTKEVPQRVYHMNPATKLLIVVRDPVTRAISDYTQAASKKADMKLFEQLAFVNGSYSVVDTNWGPVKIGVYARYLERWLLYFPLSQLLFISGERLIMDPAYEIGRVQDFLGLKRVVTEKHFYFNATKGFPCLFKSEARSTPHCLGKTKGRNHPHIDPGAIERLREFYRPFNNKFYQLTGINFAWP", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. : . .: : : ::.: : *. . :: : . * . . . . . * . : . .* *::**:::******.********:*:***:**.*:* ***** *.:** ***. ** *:.**:***********:*.* *: *. ***::***************: **:.*: **.*:* * : .::**.*..::**:**::** ** .**: *:**:*****: **: *: ***.****:* :*.***:** :****** :.*. . ********** ** * .:.:**:**:*** ***::** :*.* ", "identical_positions": 158, "similar_positions": 96, "identity": "40.41%" }, { "cls_id": "homologset.agr.MGI:1333854", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z1S8-1", "uniprot_id": "GAB2_MOUSE", "id": "Q9Z1S8-1", "name": "GRB2-associated-binding protein 2", "aln": "-----------------------------MSGGGG--DDVVCTGWLRKSPPEKKLRRYAWKKRWFILRSGRMSGDPDVLEYYKNEHSKKPLRIINLNLCEQVDAG--LTFNKKELQDSFVFDIKTSERTFYLVAETEADMNKWVQSICQICGFNQAEESTDS----------LRNLSSASHGPRSSPAEFSSS-QHLLRERKSSAPSHSSQPTLFTFEPPVSSHMQPTLS-----------------------------------------TSAPQEYLYLHQCISRRTENARSASFSQGTRQ--------KSDTAVQKLAQSNGHCINGVGGQVHGFYSLPKPS------------------------------------RHN-----TEFKDSTYDLPRSLASHGHTKSSLTGSETDNEDVYTFKMPSNTLCRELG-----------------DLLVDNMDVPTTPLSAYQIPRTFTLDKNHNAMTVATPGDSAIAPPPRPPKPSQAETS----QWGSIQQRPPISENSRSVAATIPRRNTLPAMDNSRLHRASSCETYEYPARGSGESASWSAE---------PPGKTAVGRSNSASSDDNYVPMNPGSSTLLAMERPGDNSQSVYIPMSPGPHHFDPLGYPSTALPIHRG--------PSRGS----------EIQPPPVNRNLKPDRKAKPTPLDLRNNT--------VIDELPFKS----------PVTKSWSRINHTFNSSSSQYCRPISTQS-----------ITSTDSGDSEENYVPMQNPVSASPVPSGTNSPAPKKSTGSVDYLALDFQPGSPSPHRKPSTSSVTSDEKVDYVQVDKEKTQALQN--TMQEWTDVRQSSEPSKGAKL------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9EQH1-1", "uniprot_id": "GAB2_RAT", "id": "Q9EQH1-1", "name": "GRB2-associated-binding protein 2", "aln": "-----------------------------MSGGGG--DDVVCTGWLRKSPPEKKLRRYAWKKRWFILRSGRMSGDPDVLEYYKNEHSKKPLRIINLNFCEQVDAG--LTFNKKELQDSFVFDIKTSERTFYLVAETEADMNKWVQSICQICGFNQAEESTDS----------LRNLSSASHGPRSSPAEFSSS-QHLLRERKSSAPSHSSQPTLFTFEPPMTSHMQPALS-----------------------------------------TSAPQEYLYLHQCISRRTENSRSASFSQGTRQ--------KSDTAVQKLAQSNGHCINGVSNQVHGFYSLPKPS------------------------------------RHN-----TEFKDSTYDLPRSLASHGHTKSSLTGSETDNEDVYTFKMPSNTLCREFG-----------------DLLVDNMDVPTTPLSAYQIPRTFTLDKNHNAMTVATSGDSAIAPPPRPPKPSQAETP----RWGSPQQKPPIGENSRSVAATIPRRNTLPAMDNSRLHRASSCETYEYPTRGSGESASWSAE---------SPGKTAVGRSDSASSDENYVPMNPGSSTLLAMERAGDNSQSAYIPMGPGPHHFDPLGYPSTALPIHRG--------PSRGS----------EIQPPPVNRNLKPDRKAKPTPLDLRNNT--------VIDELPFKS----------PVTKSWSRINHTFNSSSSQYCRPISTQS-----------ITSTDSGDSEENYVPMQNPVSASPVPSGTNSPAPRKSTGSVDYLALDFQPGSPSPHRKPSTSSVTSDEKVDYVQVDKEKTQALQN--TMQEWTDVRQSSEPSKGAKL------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UQC2-1", "uniprot_id": "GAB2_HUMAN", "id": "Q9UQC2-1", "name": "GRB2-associated-binding protein 2", "aln": "-----------------------------MSGGG----DVVCTGWLRKSPPEKKLRRYAWKKRWFILRSGRMSGDPDVLEYYKNDHSKKPLRIINLNFCEQVDAG--LTFNKKELQDSFVFDIKTSERTFYLVAETEEDMNKWVQSICQICGFNQAEESTDS----------LRNVSSAGHGPRSSPAELSSSSQHLLRERKSSAPSHSSQPTLFTFEPPVSNHMQPTLS-----------------------------------------TSAPQEYLYLHQCISRRAENARSASFSQGTRAS----FLMRSDTAVQKLAQGNGHCVNGISGQVHGFYSLPKPS------------------------------------RHN-----TEFRDSTYDLPRSLASHGHTKGSLTGSETDNEDVYTFKTPSNTLCREFG-----------------DLLVDNMDVPATPLSAYQIPRTFTLDKNHNAMTVATPGDSAIAPPPRPPKPSQAETP----RWGSPQQRPPISENSRSVAATIPRRNTLPAMDNSRLHRASSCETYEYPQRG-GESAGRSAESMSDGVGSFLPGKMIVGRSDSTNSEDNYVPMNPGSSTLLAMERAGDNSQSVYIPMSPGAHHFDSLGYPSTTLPVHRG--------PSRGS----------EIQPPPVNRNLKPDRKAKPTPLDLRNNT--------VIDELPFKS----------PITKSWSRANHTFNSSSSQYCRPISTQS-----------ITSTDSGDSEENYVPMQNPVSASPVPSGTNSPAPKKSTGSVDYLALDFQPSSPSPHRKPSTSSVTSDEKVDYVQVDKEKTQALQN--TMQEWTDVRQSSEPSKGAKL------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B7A7-1", "uniprot_id": "A0ACD6B7A7_DANRE", "id": "A0ACD6B7A7-1", "name": "", "aln": "-----------------------------MSGGE-----IICQGWLRKSPPEKKLRRYAWKKRWFILRSGRMSGDPDVLEYYKSDHAKKPIRIIDLHCCEQVDAG--LTFKRKEFQDSFVFDIKTAERTFYLVAETEEEMNRWVRSICQLCGFNQSEENHHD----------ERSSSIS----RSLTNELSSSLAPLIGERKTSVPAHSSQPMLFTFDIPVR-HSHGPLS-----------------------------------------NSAPQDYLFLHQCMSRKSESARSASFSQASRSS----LLVGSDSAVQRLTHGFSHCLNGMGAQLHGFYSLPKPG------------------------------------KHQQPPSRTDSQEACYVLPRNYSSEG-------ASELDSEDVYTFKTPNNTLAAPQTNE---------------QRALDNYDLP-----IYQIPRTF--DKNHNALMPSN-ADSTSAPPPRPPKPSQGSES----RWGGTLPTG-AQNGEVSTASVIPRRNTLPAVENIKLHRGSSFETSSHQRPVYFNNSGQSVESVNDGFSSYLRTKAPLTRSDSAGSDDNYVPMNPGSSSSPLSAALADSPKNNYIPMSPGPHHFDFPGF-SATLPARKGSTASLCLRPGRLS----------DVTPPPINRNLKP-RTAKPTPLDLRNNG--------IIDELPFKS----------PITMSWTRP-MPMNSISSQHCRPISTQS-----------ITSTDSADSEENYVAMQNPVSTSPAMSGTSSPAPRN-CGNVDYLALDFQPGSPGPHRKPSTSSVTSDEKVDYVQVDKEKTQALQN--TMQEWTDVRQSSEPAKGIKS------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q2WGN9-1", "uniprot_id": "GAB4_HUMAN", "id": "Q2WGN9-1", "name": "GRB2-associated-binding protein 4", "aln": "MSLPSPSPSRELCPPDPAFAPLSSWPGSGPAGGSTRSGHVLYSGWLRKSPPEKKLRLFAWRKRWFILRRGQTSSDPDVLEYYKNDGSKKPLRTINLNLCEQLDVDVTLNFNKKEIQKGYMFDIKTSERTFYLVAETREDMNEWVQSICQICGFRQ-EESTGF----------LGNISSASHGLCSSPAEPSCSHQHLPQEQEPTS------------EPPVSHCVPPTWP-----------------------------------------IPAPPGCLRSHQHASQRAEHARSASFSQGSEAP----FIMRRNTAMQNLAQHSGYSVDGVSGHIHGFHSLSKPS------------------------------------QHN-----AEFRGSTHRIPWSLASHGHTRGSLTGSEADN------------------------------------------------------------------------------------EASSGKYT----QHGGGNASRPAESMHEGVCSFLP-------------------------------------------------GRTLVGLSDSIASEGSCVPMNPGSPTLPAVKQAGDDSQGVCIPVGSCLVRFDLLGSPLTELSMHQD--------LSQGH----------EVQLPPVNRSLKPNQKANPTPPNLRNNR--------VINELSFKP----------PVTEPWSGTSHTFDSSSSQH--PISTQS-----------ITNTDSEDSGERYL-FPNPASAFPVSGGTSSSAPPRSTGNIHYAALDFQPS------KPSIGSVTSGKKVDYVQVDLEKTQALQK--TMHEQMCLRQSSEPPRGAKL------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VZZ9-1", "uniprot_id": "DOS_DROME", "id": "Q9VZZ9-1", "name": "Protein daughter of sevenless", "aln": "------------------------------------MDRTFYEGWLIKSPPTKRIWRARWRRRYFTLKQGEIP-EQFCLEYYTDHNCRKLKGVIDLDQCEQVDCG--LRLENRKQKFQYMFDIKTPKRTYYLAAETEADMRDWVNCICQVCHLHDTKQSNELPLGAVGADENRTQHTSSSGGLSNSTQNTTTTSLHSSAGTTAPQASVPNAGGSAQLRRPAVIEEQPMPSNAGNNNSDSVYVNTEYSNRETMLCDANFDQQELLSAAQQQPPPSPATALYLNHSALIQAQAAAAAAEQLQQQQQQAARLAVSANGVVRKLPEHLVLTQQTLAEAAAQQHSSVQASPALSTASGPYIPISECFSGSPRFLPGVPLPGADLAIPNNPTTPLNNLDPKFYDTPRSHNNIGLNLTNDQSYSPKITNLSLQQLANNNASKQRSDSDSESVFTDDDEWAHPLPLRENVDRSTRPSDSSIENESFVLTYSQRFSKMPEEGGAIVPPAEKSSKLAGAASLPEAGDQGTLDKLAKVLKNKNNLILDFKENEKIPRDLPQLSDTENTSPAIVARRNAHSAFIEESYDIPRSHQQPYYNVNQLLG-ERPVTSPHNSNPIAASTPNLMAADLGAVAAISAAANPGLMGEAQAVASSPTSARTLPRHCYTN--AAPTKMEGNVFRYDFMEQADCPPVNRKLKPKVAGGLPVVEDKPPEEFPAKPPVGVDQLTNKLGAAQLQQPIGPPSVDRKCKPNAYKLGNSATMSPATRRSSGAPLSMVLPHETDVHSPAAANAFFHETRTLPRQQHRHHPNSPGSMSVQHQRTASAAAAMMSLTAAAAPKQQAAAQTEHKLQYFDLDVTNKPPLLNRSSMSVGNLYSQGGNGASGMRFAGVEAGGARAPVPSSVVYRSVDFVKTEAFKRIREERESSGNK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *** **** *:: *::*:* *: *. . : ****... .:* *:*. ***:* . * ::.:: : ::*****.:**:**.***. :*. **..***:* :.: ::. . : : . . : : : .. * . .:* * :: ::: : :*: . . : .::.*.. : :. :* :.. :: : : * . . * . . . : : . * . . : . : . . * . *: ..:.. . . . . . : . : : : **:**.*** . . : : :::*. * * : . . . .* * : :* *...* : : :. .. . ..*... . * . . .:. : .*::*.::* :. .* : :* *..: . * : ", "identical_positions": 79, "similar_positions": 171, "identity": "8.59%" }, { "cls_id": "homologset.agr.MGI:1333855", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WUC4-1", "uniprot_id": "ATOX1_RAT", "id": "Q9WUC4-1", "name": "Copper transport protein ATOX1", "aln": "---MPKHEFSVDMTCGGCAEAVSRVLNKLGG--VEFNIDLPNKKVCIESEHSSDILLATLNKTGKAVSYLGPK-------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O08997-1", "uniprot_id": "ATOX1_MOUSE", "id": "O08997-1", "name": "Copper transport protein ATOX1", "aln": "---MPKHEFSVDMTCEGCAEAVSRVLNKLGG--VEFNIDLPNKKVCIDSEHSSDTLLATLNKTGKAVSYLGPK-------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00244-1", "uniprot_id": "ATOX1_HUMAN", "id": "O00244-1", "name": "Copper transport protein ATOX1", "aln": "---MPKHEFSVDMTCGGCAEAVSRVLNKLGG--VKYDIDLPNKKVCIESEHSMDTLLATLKKTGKTVSYLGLE-------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "M9PD88-1", "uniprot_id": "M9PD88_DROME", "id": "M9PD88-1", "name": "Copper transport protein ATOX1", "aln": "---MTVHEFKVEMTCGGCASAVERVLGKLGDKVEKVNINLEDRTVSVTSNLSSDELMEQLRKTGKSTTYVGVKKXDEFLSKFQKYGRLKLEV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38636-1", "uniprot_id": "ATX1_YEAST", "id": "P38636-1", "name": "Copper chaperone ATX1", "aln": "MAEIKHYQFNVVMTCSGCSGAVNKVLTKLEPDVSKIDISLEKQLVDVYTTLPYDFILEKIKKTGKEVR-SGKQL------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ::*.* *** **: **.:** ** : :*.* .: * : : . * :: :.**** . * : ", "identical_positions": 22, "similar_positions": 21, "identity": "23.91%" }, { "cls_id": "homologset.agr.MGI:1333856", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q01713-1", "uniprot_id": "KLF9_RAT", "id": "Q01713-1", "name": "Krueppel-like factor 9", "aln": "MSAAAYMDFVAAQCLVSISNRAAVPEHGGAPDAERLR--LPEREVTKEHGDPGDTWKDYCTLVTIAKSLLDLNKYRPIQTPSVCSDSLESPDEDIGSDSDVTTESGSSPSHSPEERQDSGS--APSPLSLLHSGVASKGKHASEKRHKCPYSGCGKVYGKSSHLKAHYRVHTGER------PFPCTWPDCLKKFSRSDELTRHYRTHTGEKQFRCPLCEKRFMRSDHLTKHARRHTDFHPSMIKR----------SKKALASPL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35739-1", "uniprot_id": "KLF9_MOUSE", "id": "O35739-1", "name": "Krueppel-like factor 9", "aln": "MSAAAYMDFVAAQCLVSISNRAAVPEHGGAPEAERLR--LPEREVTKEHGDPGDTWKDYCTLVTIAKSLLDLNKYRPIQTPSVCSDSLESPDEDIGSDSDVTTESGSSPSHSPEERQDSGS--APSPLSLLHSGVASKGKHASEKRHKCPYSGCGKVYGKSSHLKAHYRVHTGER------PFPCTWPDCLKKFSRSDELTRHYRTHTGEKQFRCPLCEKRFMRSDHLTKHARRHTVFHPSMIKR----------SKKALACPL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13886-1", "uniprot_id": "KLF9_HUMAN", "id": "Q13886-1", "name": "Krueppel-like factor 9", "aln": "MSAAAYMDFVAAQCLVSISNRAAVPEHGVAPDAERLR--LPEREVTKEHGDPGDTWKDYCTLVTIAKSLLDLNKYRPIQTPSVCSDSLESPDEDMGSDSDVTTESGSSPSHSPEERQDPGS--APSPLSLLHPGVAAKGKHASEKRHKCPYSGCGKVYGKSSHLKAHYRVHTGER------PFPCTWPDCLKKFSRSDELTRHYRTHTGEKQFRCPLCEKRFMRSDHLTKHARRHTEFHPSMIKR----------SKKALANAL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P33400-1", "uniprot_id": "PACC_YEAST", "id": "P33400-1", "name": "pH-response transcription factor pacC/RIM101", "aln": "MVPLEDLLNKENGTAAPQHSRESIVENGTDVSNVTKKDGLPSPNLSKRSSDCSKRPRIRCTTEAIGLNGQEDERMSPGSTSSSCLPYHSTSHLNTPP-YDLLGASAVSPTTSSSSDSSSSSPLAQAHNPAGDDDDADNDGDSEDITLYCKWDNCGMIFNQPELLYNHLCHDHVGRKSHKNLQLNCHWGDCTTKTEKRDHITSHLRVHVPLKPFGCSTCSKKFKRPQDLKKHLKIHLESGGILKRKRGPKWGSKRTSKKNKSCASDAVSSCSASVPSAIAGSFKSHSTSPQILPPLPVGISQHLPSQQQQRAISLNQLCSDELSQYKPVYSPQLSARLQTILPPLYYNNGSTVSQGANSRSMNVYEDGCSNKTIANATQFFTKLSRNMTNNYILQQSGGSTESSSSSGRIPVAQTSYVQPPNAPSYQSVQGGSSISATANTATYVPVRLAKYPTGPSLTEHLPPLHSNTAGGVFNRQSQYAMPHYPSVRAAPSYSSSGCSILPPLQSKIPMLPSRRTMAGGTSLKPNWEFSLNQKSCTNDIIMSKLAIEEVDDESEIEDDFVEMLGIVNIIKDYLLCCVMEDLDDEESEDKDEENAFLQESLEKLSLQNQMGTNSVRILTKYPKILV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . : .. .* :: *:* . : **. :::*. .* .. : ** :*. . : :: * .*.* * .:.. : . *: *. **: *... ....* * : . . . * :. .:.: * :..** ::.:.. * * . * : * * ** .* .: *.:* * *.*. * * *. *.*:* *.:.*.** : * : :: *** : . ", "identical_positions": 53, "similar_positions": 84, "identity": "8.47%" }, { "cls_id": "homologset.agr.MGI:1333857", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A6X8Z5-1", "uniprot_id": "RHG31_MOUSE", "id": "A6X8Z5-1", "name": "Rho GTPase-activating protein 31", "aln": "MKNKGAKQKLKRKGAASAFGCDLTEYLESSGQDVPYVLKSCAEFIETHGIVDGIYRLSGITSNIQRLRQEFGSDQCPDLTREVYLQDIHCVGSLCKLYFRELPNPLLTYELYEKFTEAVSHRPEEGQLARIQNVILELPPPHYRTLEYLIRHLAHIASFSSKTNMHARNLALVWAPNLLRSKKIEATICNGDAAFLAVRVQQVVIEFILNHADQIFNGGAPGALQQDESRTIT--KSLTLPALS--LPMKLVSLEEAQARSLATNHPARKER-RENSLPEIVP---PPFHTVLELPDNKRKLSSKSKKWKSIFNLGRSGSDSKSKLSRNGSVFVRGQRLSVEKATIRPAKSMDSLCSVPVEGKENKGNFSRTVTTGGFFIPATKMHASSTGSSCDLSK-EGEWGQEGMPA----------GAEGGCEVG--------GQIRPLPEQLKVFRPIGDPESEQSAPKLLGMFYTSSDSPGKS--VFTSSLFQMEPSPRHQRKALNISEPFAVSVPLRVSAVISTNSTPCRTPPKELQS-LSSLEEFSFQGSESGGWPEEEK------PLGAESFPGSVTKKAATEDTKPEPE-VPGRAECSQSPPLDPGTQV-EKKTLHVSLGSQVSKEAEKRPKAEK-----VMEESQGASQPKPSTPQESLGAGTEPLILHEMDEEDLAQALIWPEIQQELKIIESEEEFSSLPPAAQKTSPIP---ESSPAPFPFPEAPGSLPS------SSAPREVWTRDAANQSIQEAAILTDREKLEPVCSLLESESQQELSPDPASLAPLEMLLFEKVSSPARIEIGGPRNLSPPLTPAPPPPTP-LEEEPEVLLS-KEGPDREDAARDSRTDVYTEQPTPKESPGIPTPCQREEAIASPNEKQNARHAVPENKGPGLPSPTKEVDIIPQEEGGAPHSAQEPSDCDEDDTVTDPAQHGLEMVEPWE----EPQWVTSPLHSPTLKEVQESQTQGSQGHRLERRLCHRPSLRQSHSLDSKTTGNSHWTLEAPFSSSCANLETERNYEPLQPPAARTKIAGLEEKALKAFREFSGLKGLEVLPSQKGPSGIQPKPVETNFMGLAEGKEQEPQLELSNRQMKHSDVPGPDSSKESSPRAQDSTLPGEHPLQLQLKNTECGPSKGKHRPSSLNLDSATPIADLFRLENGAPFSSPGIELSELGDTKVTWMSSSHCKAAPWN--SQDTQDLDIVAHTLTGRRNSAPVSVSAVRTSFMVKMCQAKAVPVIPPKIQYTQIPQPLPSQSTGEGGAQPLERSQEEPGSTPEIPQKSTKDDSPSSLGSPEEEQPKQETGASASRRQASITSCMYEGSSCSPEPSASTLASTQDAVVQCRKRTSETEPSGDNLLSSKLERASGGPKAFHRSRPGRPQSLILF----PIMDHLPSSPTVIDSKVLLSPIRSPTQTVSPGLLCGELAENTWITPEGVTLRNKMTIPKNGQRLETSTSCFYQPQRRSVILDGRSGRQIE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A987-1", "uniprot_id": "D4A987_RAT", "id": "D4A987-1", "name": "", "aln": "MKNKGAKQKLKRKGAASAFGCDLTEYLESSGQDVPYVLKSCAEFIETHGIVDGIYRLSGVTSNIQRLRQEFGSDQCPDLTREVYLQDIHCVGSLCKLYFRELPNPLLTYELYEKFTEAVSHCPEEGQLARIQNVIQELPPPHYRTLEYLIRHLAHIASFSSKTNMHARNLALVWAPNLLRSKKIEATICNGDAAFLAVRVQQVVIEFILNHADQIFNGGAPGALQQDESRTIT--KSLTLPALS--LPMKLVSLEEAQARSLATNHPARKER-RENSLPEIVPSMGTPFHTVLELPDNKRKLSSKSKKWKSIFNLGRSGSDSKSKLSRNGSVFVRGQRLSVEKATIRPAKSMDSLCSVPVEGKENKGNFNRTVTTGGFFIPATKMHASSTGSSCDLSK-EGEWSQEGMPA----------GAEGGCEVG--------GQIRPLPEQLKVFRPIGDPESEQSAPKLLGMFYTSSDSPGKS--VFTSSLFQMEPSPRHQRKALNISEPFAVSVPLRVSAVISTNSTPCRTPPKELQS-LSSLEEFSFQGSESGGWPEEEK------PLGAEPFPGSVPKKAATEDTKPEHE-APGRAECNQSLPLDPGTPL-EKKTLDISLGSQLSKEPEKWPNAEK-----AMEESQGASQTKLSTPQESPRARTKPVLLHEMDEDDLAQALIWPEIQQELKIIESEEEFSSLPPPAQKTSPMT---ESSPAPFPSPEAPESLPS------SSAPLEVWTRDSANQSIQETAILTNREKLEPVCSLLESESEQAVSPDPSTLAPLEILLFEKVSSPARIEIGGPGNLSPPLPPAPPPPTP-LEEEPQVLLS-HEGPDREDASRDSRTDLYTEQPNSEDSPGIPRLCQREEAIASPNEKQDAKQAVPESKDPGLPSPTKEVEVIPQEEGDASHSAQEPSDCDEDDTVIDTAQHGLEMVEPWE----EPQWVTSPLHSPTLKEIQESQTQGSQGHRLERRLRHRPSLRQSHSLDSKTTGQSHWALEAPFSSSCASLETERNYEPLQTPSARIKIAGLEEKALKAFREFSGLKGLEVLPSQKGSSGIQPKPVETNFISLTEGKEQGPQLEFSNPQIKHNDVPGPDSSEGSSPGAQDSTSPGEHPLKLQLKSTECGPSKGKHRPSSLNLDSAIPIADLFRVENGASFSSPGIELSELGDTKVIWMSSSQGKAAPWS--SQDTQDLGIVAHALTGRRNSAPVSVSAVRTSFMVKMCQAKAVPVIPPKIQYTQIPQPLPSQNTGEGGAQPPERNQEEPGSTPETPQKPTKDDSPSSLGSPEEEQPKQEQGASASRRKASTTSCVAEGSFCSAEPGPSTLVSSQDAMGQCRKRTSETEPSEDNLLSSKLERASGGPKPTHRPRPGRPQSLILF----PIMDHLPSSPTVIDSKVLLSPIRSPSQTVSPGLLCGELAENTWVTPEGVTLRNKMTIPKNGQRLETSTSCFYQPQRRSVILDGRSGRQIE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q2M1Z3-1", "uniprot_id": "RHG31_HUMAN", "id": "Q2M1Z3-1", "name": "Rho GTPase-activating protein 31", "aln": "MKNKGAKQKLKRKGAASAFGCDLTEYLESSGQDVPYVLKSCAEFIETHGIVDGIYRLSGVTSNIQRLRQEFGSDQCPDLTREVYLQDIHCVGSLCKLYFRELPNPLLTYELYEKFTEAVSHCPEEGQLARIQNVIQELPPSHYRTLEYLIRHLAHIASFSSKTNMHARNLALVWAPNLLRSKEIEATGCNGDAAFLAVRVQQVVIEFILNHVDQIFNNGAPGSLENDENRPIM--KSLTLPALS--LPMKLVSLEEAQARSLATNHPARKER-RENSLPEIVPPMGTLFHTVLELPDNKRKLSSKSKKWKSIFNLGRSGSDSKSKLSRNGSVFVRGQRLSVEKATIRPAKSMDSLCSVPVEGKETKGNFNRTVTTGGFFIPATKMHSTGTGSSCDLTKQEGEWGQEGMPP----------GAEGGFDVSSDRSHLQGAQARPPPEQLKVFRPVEDPESEQTAPKMLGMFYTSNDSPSKS--VFTSSLFQMEPSPRNQRKALNISEPFAVSVPLRVSAVISTNSTPCRTPPKELQS-LSSLEEFSFHGSESGGWPEEEK------PLGAETSAASVPKKAGLEDAKAVPE-APGTVECSKGLSQEPGAHLEEKKTPESSLSSQHLNELEKRPNPEK-----VVEEGREAGEMESSTLQESPRARAEAVLLHEMDEDDLANALIWPEIQQELKIIESEEELSSLPPPALKTSPIQPILESSLGPFIPSEPPGSLPCGSFPAPVSTPLEVWTRDPANQSTQGASTAASREKPEP---------EQGLHPDLASLAPLEIVPFEKASPQATVEVGGPGNLSPPLPPAPPPPTP-LEESTPVLLS-KGGPEREDSSRKLRTDLYIDQLKSQDSPEISSLCQGEEATPRHSDKQNSKNAASEGKGCGFPSPTREVEIVSQEEEDVTHSVQEPSDCDEDDTVTDIAQHGLEMVEPWE----EPQWVTSPLHSPTLKDAHKAQVQGLQGHQLEKRLSHRPSLRQSHSLDSKPTVKSQWTLEVPSSSSCANLETERNSDPLQPQAPRREITGWDEKALRSFREFSGLKGAEAPPNQKGPSGVQPNPAETSPISLAEGKELGTHLGHSSPQIRQGGVPGPESSKESSPSVQDSTSPGEHPAKLQLKSTECGPPKGKNRPSSLNLDPAIPIADLFWFENVASFSSPGMQVSEPGDPKVTWMTSSYCKADPWRVYSQDPQDLDIVAHALTGRRNSAPVSVSAVRTSFMVKMCQARAVPVIPPKIQYTQIPQPLPSQSSGENGVQPLERSQEGPSSTSGTTQKPAKDDSPSSLESSKEEKPKQDPGAIKSSPVDATAPCMCEGPTLSPEPGSSNLLSTQDAVVQCRKRMSETEPSGDNLLSSKLERPSGGSKPFHRSRPGRPQSLILFSPPFPIMDHLPPSSTVTDSKVLLSPIRSPTQTVSPGLLCGELAENTWVTPEGVTLRNKMTIPKNGQRLETSTSCFYQPQRRSVILDGRSGRQIE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E9QGF9-1", "uniprot_id": "E9QGF9_DANRE", "id": "E9QGF9-1", "name": "", "aln": "MKNKAAKLKSKRKGTDNAFGCDLSEHLQSSGQDVPHVLKTCAEFIEKHGIVDGIYRLSGITSNIQKLRQEFSSELCPDLTKEVYLQDIHCVGSLCKLYFRELPNPLLTYELYSKFTHAVSVKEEQEQLRNIRSAIKELPESHFRTLEYLTKHLAYLATLSHQTNMHARNLALVWAPNLLRSKEVEVPSCNGDIAFLEVRVQQSVVEFILNHTEQIFNLEFQPSKARDGPSMACGEKYATLPASTQCGPMKLMSLEEAQARSLSPNHPVMKERQRENSLPDTST--AAMYHTVIDLSDSRRKFSGKSKKWKSIFSLGRSVIDSKGKLSRNGSVFMRAQ-NSSEKTAIRPSKSMDSLCSFQAPDEDK----AAAEGANGMFIPIHKSRTLGS-DINYLNKKDPKWDLESQTASGGSLNEKREGASNASSSSSSPSSSLSPLQKSLPEQLKVFKGDERGGCQPTSPKNRRMLYSGSANNGSSRPSFPGSLFPLESSPRHQRKALNISEPFAVSVPLRVSAVINSNSTPCRAPGKERDRGLGGLFRPSKEAGPLEGHRRESMGAAGLCGAGNFSFTDWETGLAGRAIGSGHRENSSGGSGCSIYSNSSSFPMENEEQSGEGDFTDAIAMATTKSKDAEVRELIATVENFQPQASSETKAIGEELETTSTKQEMAKLDKLELIDKVPSSGMHDKVSITEVKT--TNMPNDGVKPCITKINGNQGNLKLSAQARRSSLPSN---TVSSKGLFIDLTKNVMFDHPGATTFNSVMKHMP-------ERLLSCDGDWNYLDSDSDRTEHKARNIITTSLQLSPFLHLKETDILQDAEPCIEEEPKIDLCEKDGTSKSDSKDNTSVSVKLDLHTDEESLRTSDICEKENKKVSDEPRKLDLAGRIKGNLERLSTCLNEKHLTLEIQDDVDACGSN-----------------LDQVEPWEDLCSAQQWVTSPLHSPKLEDLFPTQREILPCQKVHCQVLDKPNADELPNSRNPEAKEPAALDEIAPTQTEAAVTAELGNSDFPTGKKN------ADTDVACFAQITAHFDRDKFKFEGAKDDIKLEIPQVKQLKTFNDPEETTGMQN--------------MSKAKQKRSQRFHRQTSHEFCIMEKSQGSG--KPKLRPCSLNLDLG---HQGFRDISNSQYLKSGKQ----------WMTP---EAKDGS--SSLELELFLSGPKAPMRRNSAPVSVSSVRTAFMIKTCQAKAVPVIPPKIQYSHIPHTLPERKNAEKSTDQVNKSTPE---KKPTKSKLGKASSLFPLQKVCREDRQSTEPPSGIQRHKSMNSATCNEN--------YKPTSIPDLPVLRRKRSANGDTFMD---RPRPERSSLLQRSSFRNRP-RPQSLILFSPPFPIMDYPSVGD---DNKQALSPIKAETSPFDA--YANELAEN-LKTTEGVTLRNKMTLPKSGQRLETSTSCFYQPQRRSMIFDNRSNRQIE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****.** * ****: .******:*:*:*******:***:******.************:*****:*****.*: *****:*******************************.***.*** *: ** .*:..* *** .*:****** :***::*::* :********************::*.. **** *** ***** *:******.:**** : .* * **** : ****:**********:.***. *** ******: . . :***::*.*.:**:*.*********.**** ***.*********:*.* * **::***:********. . .::. : :.*:*** * :: .: . *.* : :*. *. .. **... . . :. *******: .: ::** *:*:.. . ..* *..*** :*.***:***********************.:******:* ** : *..* . * ... * .*. * . . . *. . * .* *. .. . *::: . .: . * ..* .:*: : .. : .: *. : : : ::*: :* : : . :::::.* * : :.:* . *.. :.. : ***. * : . . . :: . * * * * . . .*. .: . * . . * :**.. : *. : *..:.*: . ..: : . ::* . *: *: . :: . :.: :.: .* .: : : .. . .: *: ***** **********.*:: :* : :::. :: .:*. : . . : :. * . :.: * : :* . . : . . :. : .* :::. . : : . ..:: : :.. : :. * . : *: .. * .* : *. .* * * **.***** . : * . : : ..* : **:. :* *. :* : . . **********:***:**:* ***:***********::**:.**.:...* ..: ::. . .* * .* .* . .*. :. . : .. : . * * *** :: :. * .: **.* :. .* ** ******** ****: . . *.* ****:: :..... ..***** *.**********:**.******************:*:*.**.****", "identical_positions": 508, "similar_positions": 380, "identity": "34.12%" }, { "cls_id": "homologset.agr.MGI:1333861", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZFR1-1", "uniprot_id": "D3ZFR1_RAT", "id": "D3ZFR1-1", "name": "Sulfotransferase", "aln": "MAPSGPSGAQLSPAEPLSRSIFRKFLLMLCSLLTSLYVFYCLAERCPPGSGPVA---------GVPGRGVPAG-PKELAMWPAGAPRKRLLQLRQRRRRGRPGP---GDSSDPDEQSPGLAAAPGGSGAGSSVAEAQPGT--LALLLDEG---SKQLPQAIIIGVKKGGTRALLEFLRVHPDVRAMGAEPHFFDRSYHKGLAWYRDLMPRTLEGQITMEKTPSYFVTREAPARISAMSKDTKLIVVVRDPVTRAISDYTQTLSKRPDIPSFESLTFRNRSAGLIDTSWSAIQIGLYAKHLEPWLRHFPLGQMLFVSGERLVSDPAGELRRVQDFLGLKRIITDKHFYFNQTKGFPCLKKAEGSGKPHCLGKTKGRAHPTIAREVLRQLRDFYRPFNRKFYQMTGRDFGWDG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BKN6-1", "uniprot_id": "HS3SA_MOUSE", "id": "Q8BKN6-1", "name": "Heparan sulfate glucosamine 3-O-sulfotransferase 3A1", "aln": "MAPSGPTGAQPSPAEPLSRSIFRKFLLMLCSLLTSLYVFYCLAERCPPGSGPVA---------GVPGRGVPAG-PRELAMWPAGAPRKRLLQLRQRRRRGRSGP---GDSSDQEEQSPGLAAAPGGSGAGSSVAEAQPGT--LALLLDEG---SKQLPQAIIIGVKKGGTRALLEFLRVHPDVRAVGAEPHFFDRSYHKGLAWYRDLMPRTLEGQITMEKTPSYFVTREAPARISAMSKDTKLIVVVRDPVTRAISDYTQTLSKRPDIPSFESLTFRNRSAGLIDTSWSAIQIGLYAKHLEPWLRHFPLGQMLFVSGERLVSDPAGELRRVQDFLGLKRIITDKHFYFNQTKGFPCLKKAEGSGKPHCLGKTKGRAHPTIAREVLRQLRDFYRPFNRKFYQMTGRDFGWDG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y663-1", "uniprot_id": "HS3SA_HUMAN", "id": "Q9Y663-1", "name": "Heparan sulfate glucosamine 3-O-sulfotransferase 3A1", "aln": "MAPPGPASALSTSAEPLSRSIFRKFLLMLCSLLTSLYVFYCLAERCQTLSGPVVGLSGGGEEAGAPGGGVLAGGPRELAVWPAAAQRKRLLQLPQWRRRRPPAPRDDGEEAAWEEESPGLSGGPGGSGAGSTVAEAPPGT--LALLLDEG---SKQLPQAIIIGVKKGGTRALLEFLRVHPDVRAVGAEPHFFDRSYDKGLAWYRDLMPRTLDGQITMEKTPSYFVTREAPARISAMSKDTKLIVVVRDPVTRAISDYTQTLSKRPDIPTFESLTFKNRTAGLIDTSWSAIQIGIYAKHLEHWLRHFPIRQMLFVSGERLISDPAGELGRVQDFLGLKRIITDKHFYFNKTKGFPCLKKAEGSSRPHCLGKTKGRTHPEIDREVVRRLREFYRPFNLKFYQMTGHDFGWDG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VWJ7-1", "uniprot_id": "Q9VWJ7_DROME", "id": "Q9VWJ7-1", "name": "", "aln": "MRDTAATSAQ--PAMIVMSIWCSSLSLSSRSLAIALVICVTLVYFSYSFN-----------------ACLLASISRSLQQ----SNLRNLLALTSSPRNETNNA---ANSSSSNSSSSRNSSSTTGAPPAQTVTSSLDGAPKYQLLRQQGLRPSRHLPDTLIIGVKKSGTRALLEFIRLHPDVRAAGSEVHFFDRHYQRGLRWYRHHMPYTIEGQITMEKTPSYFVTKEVPQRVYHMNPATKLLIVVRDPVTRAISDYTQAASKKADMKLFEQLAFVNGSYSVVDTNWGPVKIGVYARYLERWLLYFPLSQLLFISGERLIMDPAYEIGRVQDFLGLKRVVTEKHFYFNATKGFPCLFKSEARSTPHCLGKTKGRNHPHIDPGAIERLREFYRPFNNKFYQLTGINFAWP-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* ...:.* .* : .: * ** :* : *. . . . : *. .:.* : :.** * . *. . .:.: :..*. :... *: ...:*:.: *: ** ::* *::**:::******.********:*:****** *:* ***** *.:** ***. ** *::**************:*.* *: *. ***::***************: **:.*: **.*:* * : .::**.*..::**:**::** ** :**: *:**:*****: *** *: **********::*:****** ******* *:*. . ********** ** * .:.:**:****** ****:** :*.* ", "identical_positions": 185, "similar_positions": 107, "identity": "45.01%" }, { "cls_id": "homologset.agr.MGI:1333863", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q61409-1", "uniprot_id": "PDE3B_MOUSE", "id": "Q61409-1", "name": "cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B", "aln": "MRKDERERDAPAMRSPPPPP----ASAASPPESLRNGYVKSCVSPLRQDPPRSFFFHLCRFCNVEP--PAASLR--------AGARLSLGVLAAFVLAALLGARPERWAAAAAGLRTLLSACSLSLSPLFSIACAFFFLTCFLTRAQRGPG--RGAGSWWLLALPACCYLGDFAAWQWWSWLRGEP------------AAAGRLCLVLSCVG-LLTLAPRVRLRHGVLVLLFAGLVWWVSFSGLGALPPALRPLLSCLVGGAGCLLALGLDHFFHVRGASPPPRSASTAEEKVPVIRPRRRSSCVSLGESAAGYYGSGKMFRRPSLPCISREQMILWDWDLKQWCKPHYQNSGGGNGVDLSVLNEARNMVSDLLIDPSLPPQVISSLRSISSLMGAFSGSCRPKINSFTPFPGFYPCSEVEDPVEKGDRKLHKGLSGRTSFPTPQLRRSSGASSLLTNEHCSRWDRSSGKRSYQELSVSSHGCHLNGPFSSNLFTIPKQRSSSVSLTHHAGLRRAGALPSHSLLNSSSHVPVSAGSLTNRSPIGFPDTTDFLTKPNIILHRSLGSVSSAADFHQYLRNSDSNLCSSCGHQILKYVSTCEPDGTDHPSEKSGEEDSSVFSKEPLNIVETQ-EEETMKKACRELFLEGDSHLMEEAQ---QPNIDQEVSLDPMLVEDYDSLIEKMNNWNFQIFELVEKMGEKSGRILSQVMYTLFQDTGLLETFKIPTQEFMNYFRALENGYRDIPYHNRVHATDVLHAVWYLTTRPIPGLPQIHNNHETETKADSDGRLGSGQIAYISSKSCCIPDMSYGCLSSNIPALELMALYVAAAMHDYDHPGRTNAFLVATNAPQAVLYNDRSVLENHHAASAWNLYLSRPEYNFLLNLDHMEFKRFRFLVIEAILATDLKKHFDFLAEFNAKANDVNSNGIEWSSENDRLLVCQVCIKLADINGPAKDRDLHLRWTEGIVNEFYEQGDEEAALGLPISPFMDRSSPQLAKLQESFITHIVGPLCNSYDAAGLLPGQWIETEEGDDTESDDDDDDDDGDGG---EELDSDDEETEDNLNPKPQRRKGRRRIFCQLMHHLTENHKIWKEIIEEEEEKCKAEGNKLQVDNASLPQADEIQVIEEADEEEEQMFE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63085-1", "uniprot_id": "PDE3B_RAT", "id": "Q63085-1", "name": "cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B", "aln": "MRKDERERDTPAMRSPPPPPPPATATAASPPESLRNGYVKSCVSPLRQDPPRSFFFHLCRFCNVEP--PAASLR--------AGARLSLAALAAFVLAALLGAGPERWAAAATGLRTLLSACSLSLSPLFSIACAFFFLTCFLTRAQRGPD--RGAGSWWLLALPACCYLGDFAAWQWWSWLRGEPAA----------AAAGRLCLVLSCVG-LLTLAPRVRLRHGVLVLLFAGLVWWVSFSGLGALPPALRPLLSCLVGGAGCLLALGLDHFFHVRGASPPPRSASTADEKVPVIRPRRRSSCVSLGESAAGYYGSGKMFRRPSLPCISREQMILWDWDLKQWCKPHYQNSGGGNGVDLSVLNEARNMVSDLLIDPSLPPQVISSLRSISSLMGAFSGSCRPKINSFTPFPGFYPCSEVEDPVEKGDRKLHKGLSSKPSFPTAQLRRSSGASGLLTSEHHSRWDRSGGKRPYQELSVSSHGCHLNGPFSSNLMTIPKQRSSSVSLTHHAGLRRAGALPSPSLLNSSSHVPVSAGCLTNRSPVGFLDTSDFLTKPSVTLHRSLGSVSSAADFHQYLRNSDSSLCSSCGHQILKYVSTCEPDGTDHHNEKSGEEDSTVFSKERLNIVETQ-EEETVKEDCRELFLEGDDHLMEEAQ---QPNIDQEVLLDPMLVEDYDSLIEKMSNWNFQIFELVEKMGEKSGRILSQVMYTLFQDTGLLETFKIPTQEFMNYFRALENGYRDIPYHNRVHATDVLHAVWYLTTRPIPGLQQLHNNHETETKADSDARLSSGQIAYLSSKSCCIPDKSYGCLSSNIPALELMALYVAAAMHDYDHPGRTNAFLVATNAPQAVLYNDRSVLENHHAASAWNLYLSRPEYNFLLNLDHMEFKRFRFLVIEAILATDLKKHFDFLAEFNAKANDVNSNGIEWSSENDRLLVCQVCIKLADINGPAKDRDLHLRWTEGIVNEFYEQGDEEATLGLPISPFMDRSSPQLAKLQESFITHIVGPLCNSYDAAGLLPGQWIEAEEGDDTESDDDDDDDDDDDDDDDEELDSDDEETEDNLNPKPQRRKGRRRIFCQLMHHLTENHKIWKEIIEEEE-KCKAEGNKLQVDNASLPQADEIQVIEEADEEEEQMFE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q13370-1", "uniprot_id": "PDE3B_HUMAN", "id": "Q13370-1", "name": "cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B", "aln": "MRRDER--DAKAMRSLQPPD-----GAGSPPESLRNGYVKSCVSPLRQDPPRGFFFHLCRFCNVELRPPPASPQQPRRCSPFCRARLSLGALAAFVLALLLGAEPESWAAGAAWLRTLLSVCSHSLSPLFSIACAFFFLTCFLTRTKRGPGPGRSCGSWWLLALPACCYLGDFLVWQWWSWPWGDGDAGSAAPHTPPEAAAGRLLLVLSCVGLLLTLAHPLRLRHCVLVLLLASFVWWVSFTSLGSLPSALRPLLSGLVGGAGCLLALGLDHFFQIREAPLHPRLSSAAEEKVPVIRPRRRSSCVSLGETAASYYGSCKIFRRPSLPCISREQMILWDWDLKQWYKPHYQNSGGGNGVDLSVLNEARNMVSDLLTDPSLPPQVISSLRSISSLMGAFSGSCRPKINPLTPFPGFYPCSEIEDPAEKGDRKLNKGLN-RNSLPTPQLRRSSGTSGLLPVEQSSRWDRNNGKRPHQEFGISSQGCYLNGPFNSNLLTIPKQRSSSVSLTHHVGLRRAGVLSSLSPVNSSNHGPVSTGSLTNRSPIEFPDTADFLNKPSVILQRSLGNAPNTPDFYQQLRNSDSNLCNSCGHQMLKYVSTSESDGTDCCSGKSGEEEN-IFSKESFKLMETQQEEETEKKDSRKLFQEGDKWLTEEAQSEQQTNIEQEVSLDLILVEEYDSLIEKMSNWNFPIFELVEKMGEKSGRILSQVMYTLFQDTGLLEIFKIPTQQFMNYFRALENGYRDIPYHNRIHATDVLHAVWYLTTRPVPGLQQIHNGCGTGNETDSDGRINHGRIAYISSKSCSNPDESYGCLSSNIPALELMALYVAAAMHDYDHPGRTNAFLVATNAPQAVLYNDRSVLENHHAASAWNLYLSRPEYNFLLHLDHVEFKRFRFLVIEAILATDLKKHFDFLAEFNAKANDVNSNGIEWSNENDRLLVCQVCIKLADINGPAKVRDLHLKWTEGIVNEFYEQGDEEANLGLPISPFMDRSSPQLAKLQESFITHIVGPLCNSYDAAGLLPGQWLEAEEDNDTESGDDEDG---------EELDTEDEEMENNLNPKPPRRKSRRRIFCQLMHHLTENHKIWKEIVEEEE-KCKADGNKLQVENSSLPQADEIQVIEEADEEE-----", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:*** *: **** ** *.************************.************ *.** : . *****..******* **** ** ***.*: ******.** *********************::***. *..***************** .****** *: ****** ******* ***** :**** *****:*.:******:.**:**.******* *****************::* *. ** :*:*:*******************:**.**** *:************************ ***************************** *******************************.:***********:***.*******:***. : *:**.*******:*.**. *: *****..***.:**:.:**:**:*****.***:***************.******.*.* * :***.* ***:*.******: * **:***.**.: *:****....:.**:* ******.**.*****:******.*.**** . *****:. :**** ::::*** **** *: .*:** ***. * **** *.**:*** ** :***:********.**** ******************************* ******:********************:****************:*** *:**. * .::***.*:. *:***:*****. ** ***************************************************************************:***:*******************************************.********************** *****:***************** *********************************************:*:**.:****.**:*. ****::*** *:****** ***.**********************:**** ****:******:*:****************** ", "identical_positions": 885, "similar_positions": 135, "identity": "77.9%" }, { "cls_id": "homologset.agr.MGI:1333864", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7M0E7-1", "uniprot_id": "RM14_RAT", "id": "Q7M0E7-1", "name": "Large ribosomal subunit protein uL14m", "aln": "MAV-LTGLFGFFAY-----VRGAVSQRCFSTSGSLSAIQKMTRVRVVDNSALGNTPYH--RPPRCIHVYNKSGVGKVGDQILLAIRGQKKKALIVGHRMPGSRMTPKFDSNNVVLIEDNGNPVGTRIKIPIPTSLR--------RREGEYSKVLAIAQNFV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D1I6-1", "uniprot_id": "RM14_MOUSE", "id": "Q9D1I6-1", "name": "Large ribosomal subunit protein uL14m", "aln": "MAA-LTGLWGSFAH-----VSRAFSQRCFSTSGSLSAVQKMTRVRVVDNSALGSTPYH--RPPRCIHVYNKSGVGKVGDQILLAIRGQKKKALIVGHRMPGSRMTPKFDSNNVVLIEDNGNPVGTRIKIPIPTSLR--------RREGEYSKVLAIAQNFV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6P1L8-1", "uniprot_id": "RM14_HUMAN", "id": "Q6P1L8-1", "name": "Large ribosomal subunit protein uL14m", "aln": "MAF-FTGLWGPFTC-----VSRVLSHHCFSTTGSLSAIQKMTRVRVVDNSALGNSPYH--RAPRCIHVYKKNGVGKVGDQILLAIKGQKKKALIVGHCMPGPRMTPRFDSNNVVLIEDNGNPVGTRIKTPIPTSLR--------KREGEYSKVLAIAQNFV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZUH5-1", "uniprot_id": "RM14_DANRE", "id": "Q7ZUH5-1", "name": "Large ribosomal subunit protein uL14m", "aln": "MALSLSGLI----------LPKLMQQRAFSVSSAVSAIQKLTRVRVVDNSTLGNAHHH--RPPKVIHVYNKNGVGKVGDRVLLAIKGQKKKAIIVGHKMPGARMTPRFDSNNVVLIEDNGNPTGTRIKAPLPTHLR--------KLEGEYSKLLAIAQRFV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W4Z2-1", "uniprot_id": "Q9W4Z2_DROME", "id": "Q9W4Z2-1", "name": "Large ribosomal subunit protein uL14m", "aln": "MALRILKTVRQVAQPLAVTLGGQQTQQLIHTTPACCEIRKLARLRVVDNSDLGKKAMAEGRPPRCIHVYNKRGVGFIGDKVLVAIKGQMKKGILVGLKQNQKPKQPKFDSNNLVLIDDNGSPLGTRIHVPIPTILRTILKEKTLAKGADYTKVLAIASRYV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** : : :: : .: : . ::*::*:****** **. *.*: ****:* *** :**::*:**:** **.::** *:*****:***:***.* ****: *:** ** .:*:*:****..:*", "identical_positions": 62, "similar_positions": 39, "identity": "38.51%" }, { "cls_id": "homologset.agr.MGI:1333865", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O14593-1", "uniprot_id": "RFXK_HUMAN", "id": "O14593-1", "name": "DNA-binding protein RFXANK", "aln": "MELTQPAEDLIQTQQTPASELGDPEDPGEEAADGSDTVVLSLFPCTPEPVNPEPDASVSSPQAGSSLKHSTTLTNRQRGNEVSALPATLDSLSIHQLAAQGELDQLKEHLRK----------GDNLVNKPDERGFTPLIWASAFGEIETVRFLLEWGADPHILAKERESALSLASTGGYTDIVGLLLERDVDINIYDWNGGTPLLYAVRGNHVKCVEALLARGADLTTEADSGYTPMDLAVALGYRKVQQVIEN---------------------------------------HILKLFQSNLVPADPE--------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Z205-1", "uniprot_id": "RFXK_MOUSE", "id": "Q9Z205-1", "name": "DNA-binding protein RFXANK", "aln": "MEPTQVAENLVPNQQPPVPDLEDPEDTRDESPENSDTVVLSLFPCTPDAVNPEADASASSLQG-SFLKHSTTLTNRQRGNEVSALPATLDSLSIHQLAAQGELSQLKDHLRKGACPACTCLSGNNLINKPDERGFTPLIWASAFGEIETVRFLLDWGADPHILAKERESALSLASMGGYTDIVRLLLDRDVDINIYDWNGGTPLLYAVRGNHVKCVEALLARGADLTTEADSGYTPMDLAVALGYRKVQQVMES---------------------------------------HILRLFQSTLGPVDPE--------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6A1G6-1", "uniprot_id": "A0A8I6A1G6_RAT", "id": "A0A8I6A1G6-1", "name": "", "aln": "MEPTQVAENLIPNQQSLAPDLEDPEDRRDESPDSSDTVVLSLFPCTPDAVNPEADASASSLQG-SFLKHSTTLTNRQRGNEVSALPATLDSLSIHQLAAQGELSQLKDHLRK----------GDNLVNKPDERGFTPLIWASAFGEIETVRFLLDWGADPHILAKERESALSLASMGGYTDIVRLLLDRDVDINIYDWNGGTPLLYAVRGNHVKCVEALLARGADLTTEADSGYTPMDLAVALGYRKGGLVYSSGLRACGWGGCRGYTGCSQGCQILTINMVLSTQAGSGTSHSALRLQRGHQDKTRVEATLGEQTLRNSPGPGVGVGLSHPLHTHTSFLMVVGWVSQASVSVTITEYHRRVMFLMFYLDSWFWRQEELRFGG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VL58-1", "uniprot_id": "Q9VL58_DROME", "id": "Q9VL58-1", "name": "DNA-binding protein RFXANK", "aln": "--------------------MVAPANTIQTNANSDDDEGVRSAPTSMLVLDAKRKSAFLPYRP-----QSTVLTNLQRGNTEATFCPVEVSLSFHERAGQGEITEEQVAAER---------ARQQNIDYKDAHGFTALHWAASYGQLVSVQLLVAAGANVNTMAPDLISPLLLAAAGGHNEIVRFLLEHGADSGHMDIVGNTALMYAAAGNHPHTCNELLAKDLDLSATNEDGDTAYSLAVEHGAHLAQALLEQY--------------------------------------MTAIITAGAFGSI-----------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * : : .:..* : * : ::.: .:: . : :**.*** **** ::: .. ***:*: *.***: : : .: :: :: * :***.* **:::*:: :*::*: **: : :* : *.* **: **:.:** :**::..* . * *.*.*:**. *** : : ***:. **:: :.* *. .*** * : : .. : . ", "identical_positions": 64, "similar_positions": 83, "identity": "16.71%" }, { "cls_id": "homologset.agr.MGI:1333868", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7TNB2-1", "uniprot_id": "TNNT1_RAT", "id": "Q7TNB2-1", "name": "Troponin T, slow skeletal muscle", "aln": "MSDTEEQEYEEEQAEDEEAV-EEEAPEEPEPVAEREEERPKPSRPVVPPLIPPKIPEGERVDFDDIHRKRMEKDLLELQTLIDVHFEQRKKEEEELIALKDRIERRRAERAEQQRFRTEKERERQAKLAEEKMRKEEEEAKKRAEDDAKKKKVLSNMGAHFGGYLVKAEQKRGKRQTGREMKLRILSERKKPLNIDYMGEDQLR----------------EKAQELSEWIHQLESEKFDLMEKLKQQKYEINVLYNRIS---HAQKFRKGAGKGRVGGRWK------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88346-1", "uniprot_id": "TNNT1_MOUSE", "id": "O88346-1", "name": "Troponin T, slow skeletal muscle", "aln": "MSDTEEQEYEEEQAEDEEAVEEEEAPEEPEPVAEREEERPKPSRPVVPPLIPPKIPEGERVDFDDIHRKRMEKDLLELQTLIDVHFEQRKKEEEELIALKDRIERRRAERAEQQRFRTEKERERQAKLAEEKMRKEEEEAKKRAEDDAKKKKVLSNMGAHFGGYLVKAEQKRGKRQTGREMKLRILSERKKPLNIDYMGEDQLR----------------EKAQELSEWIHQLESEKFDLMEKLKQQKYEINVLYNRIS---HAQKFRKGAGKGRVGGRWK------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P13805-1", "uniprot_id": "TNNT1_HUMAN", "id": "P13805-1", "name": "Troponin T, slow skeletal muscle", "aln": "MSDTEEQEYEEEQPEEEAAEEEEEAPEEPEPVAEPEEERPKPSRPVVPPLIPPKIPEGERVDFDDIHRKRMEKDLLELQTLIDVHFEQRKKEEEELVALKERIERRRSERAEQQRFRTEKERERQAKLAEEKMRKEEEEAKKRAEDDAKKKKVLSNMGAHFGGYLVKAEQKRGKRQTGREMKVRILSERKKPLDIDYMGEEQLRARSAWLPPSQPSCPAREKAQELSDWIHQLESEKFDLMAKLKQQKYEINVLYNRIS---HAQKFRKGAGKGRVGGRWK------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P19351-1", "uniprot_id": "TNNT_DROME", "id": "P19351-1", "name": "Troponin T, skeletal muscle", "aln": "MSDDEEYTSSEEEEVVEETREETKPPQTP----AEGEGDPEFIKRQDQKRSDLDDQLKEYITEWRKQRSKEEDELKKLKEKQAKRKVTRAEEEQKMAQRKKEEEERRVREAEEKKQREIEE--KRMRLEEAEKKRQAMLQAMKDKDKKGPNFTIAKKDAGVLGLSSAAMERNKTKEQLEEEKKISLSFRIKPLAIEGFGEAKLR----------------EKAQELWELIVKLETEKYDLEERQKRQDYDLKELKERQKQQLRHKALKKGLDPEALTGKYPPKIQVASKYERRVDTRSYDDKKKLFEGGWDEISKDSNEKIWNEKKEQYTGRQKSKLPKWFGERPGKKAGEPETPEGEEDAKADEDIVEDDEEVEEEVVEEEDEEAEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** ** .**: * : * :.*: * * *: : . * : :*.: *.:* :*: : * :**::: *.. *.** ..**::: * :* :: :* * : ::: : :*. : .::: .* . * * ::. .:: .* * ** * *** *: :** :** ****** : * :**:**:** : *:*.*::: * :* . : : ::** . : *:: ", "identical_positions": 69, "similar_positions": 78, "identity": "16.47%" }, { "cls_id": "homologset.agr.MGI:1333869", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4QQV7-1", "uniprot_id": "CH25H_RAT", "id": "Q4QQV7-1", "name": "Cholesterol 25-hydroxylase", "aln": "-----MACHNVSELQDLGCSNQLLLQPLWDSIRTGEASARSPFFPVIFSIFTYLGFCLPFVVLDVLCPWVP---ILRRYKIHPDFSPS----VRQLLPCLGLTLYQHLVFVFPVTLMHWA-------------RSPALLPREAPELSQLL--------SHVLICLLLFDTEIFAWHLLHHKVPWLYRTFHKVHHQNSSSFALATQYMSVWELLSLTFFDV-LNVAMLQCHPLTILVFHVVNIWLSVEDHSGYDFPWSTHRLVPFGWYGGVAHHDLHHSQFNCN---FAPYFTHWDKMLGT-----------LRCAPHSKRLCAGSESCLDSGEQCTVHLNQKKKQT------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z0F5-1", "uniprot_id": "CH25H_MOUSE", "id": "Q9Z0F5-1", "name": "Cholesterol 25-hydroxylase", "aln": "-----MGCYNGSELQDLGCSSQLLLQPLWDTIRTREAFTRSPIFPVTFSIITYVGFCLPFVVLDVLYPWVP---ILRRYKIHPDFSPS----VKQLLPCLGLTLYQHLVFVFPVTLLHWV-------------RSPALLPQEAPELVQLL--------SHVLICLLLFDTEIFAWHLLHHKVPWLYRTFHKVHHQNSSSFALATQYMSFWELLSLTFFDV-LNVAVLRCHPLTIFTFHVINIWLSVEDHSGYDFPWSTHRLVPFGWYGGVAHHDMHHSQFNCN---FAPYFTHWDKMLGT-----------LRSAPLPESLCACGERCVNSRERCAVHLIQKKKQT------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95992-1", "uniprot_id": "CH25H_HUMAN", "id": "O95992-1", "name": "Cholesterol 25-hydroxylase", "aln": "-----MSCHNCSDPQVLCSSGQLFLQPLWDHLRSWEALLQSPFFPVIFSITTYVGFCLPFVVLDILCSWVP---ALRRYKIHPDFSPS----AQQLLPCLGQTLYQHVMFVFPVTLLHWA-------------RSPALLPHEAPELLLLL--------HHILFCLLLFDMEFFVWHLLHHKVPWLYRTFHKVHHQNSSSFALATQYMSVWELFSLGFFDM-MNVTLLGCHPLTTLTFHVVNIWLSVEDHSGYNFPWSTHRLVPFGWYGGVVHHDLHHSHFNCN---FAPYFTHWDKILGT-----------LRTASVPAR--------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5PRC0-1", "uniprot_id": "CH25H_DANRE", "id": "Q5PRC0-1", "name": "Cholesterol 25-hydroxylase-like protein", "aln": "---------------------MFGLQHIWDCILQYEAQLRSPFFPVLFSITVYLSFCLPFVLLDALSPKVE---LIRRYKIQQKASVS----WTMMWSCLALSLYNHVVYIFPLSVLHWY-------------WRPVSYLAEAPGVLRVV--------WDLAACLLLFDFQYFVWHLLHHKVPWLYRTFHKVHHKYTSTFALATEYSGAWETLSLGFFAA-VNPMLLGVHPMTEMLFHMLNMWLSVEDHCGYDLPWATHRLMPFGLYGGAPHHDVHHQKFKSN---YAPYFTHWDKLFGT-----------LHFE-------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P38992-1", "uniprot_id": "SUR2_YEAST", "id": "P38992-1", "name": "Sphingolipid C4-hydroxylase SUR2", "aln": "MNVTSNATAAGSFPLAFGLKTSFGFMHYAKAPAINLRPKESLLPEMSDGVLALVAPVVAYWALSGIFHVIDTFHLAEKYRIHPSEEVAKRNKASRMHVFLEVILQHIIQTIVGLIFMHFEPIYMTGFEENAMWKLRADLPRIIPDAAIYYGYMYGMSALKIFAGFLFVDTWQYFLHRLMHMNKTLYKWFHSVHHELYVPYAYGALFNNPVEGFLLDTLGTGIAMTLTHLTHREQIILFTFATMKTVDDHCGYALPLDPFQWL---FPNNAVYHDIHHQQFGIKTNFAQPFFTFWDNLFQTNFKGFEEYQKKQRRVTIDKYKEFLQERELEKKEKLKNFKAMNAAENEVKKEK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . .* : : .: . :. :.: *. : : .:*:*: . . : : * * : : :. : .:*: . * .: :*:.* : * * * **: **.***: .:* .: : . * : * : : : : :. . :*:**.** :* ..: : ... :**:**.:* : *:**.**::: * : ", "identical_positions": 40, "similar_positions": 79, "identity": "11.36%" }, { "cls_id": "homologset.agr.MGI:1333870", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AL43-1", "uniprot_id": "A0A8I6AL43_RAT", "id": "A0A8I6AL43-1", "name": "Arginyl-tRNA--protein transferase 1", "aln": "MASWSAPSPSLVEYFEGQTSFQCGYCKSNFG--------------------------SRSHGMWAHSMTVQDYQDLIDRGWRRSGKYVYKPVMNQTCCPQYTIRCHPLQFQPSKSHKKVLKKMLKFLAKGEISKGNCEDEPMDSTMEDAVDGDFALMNKLDIKCDLKTLSSDLKVSIESEEKEKEKSLKKEGSKDLIHPQ-AIEEKLGSGEPSHSIKVHVGPKPGKGADLSKPPCRKAKEMRKERKRLKLMQQSSAGAFEGFQAQGQPVSLLP-KAKSNQPKSLEDLIFESLPEDASHKLEVRVVRSSPPSPQFKATFQESYQVYKRYQMIIHKDPPDKPTVSQVRLVPASFEDPEFKSSFNQSLSLYTKYQVAIHQDEPDICDKSEFTRFLCNSPLEAEHPANGPECGYGSFHQQYWLD--GKIIAVGVIDILPYCVSSVYLYYDPDYSFLSLGVYSALREIAFTRQLHEKTSQLSYYYMGFYIHSCPKMRYKGQYRPSDLLCPETYVWVPIEQCLPS-LDNSKYCRFNQDPQAEDEGR--SKELDRLRVFHR-RSAMPYGVYKNHQEDPSEEAVVLEYANLVG-QKCSETMLLFRH--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z2A5-1", "uniprot_id": "ATE1_MOUSE", "id": "Q9Z2A5-1", "name": "Arginyl-tRNA--protein transferase 1", "aln": "MASWSAPSPSLVEYFEGQTSFQCGYCKNKLG--------------------------SRSYGMWAHSMTVQDYQDLIDRGWRRSGKYVYKPVMDQTCCPQYTIRCHPLQFQPSKSHKKVLKKMLKFLAKGEISKGNCEDEPMDSTVEDAVDGDFALINKLDIKCDLKTLS-DLKGSIESEEKEKEKSIKKEGSKEFIHPQ-SIEEKLGSGEPSHPIKVHIGPKPGKGADLSKPPCRKAREMRKERQRLKRMQQASAAASE---AQGQPVCLLP-KAKSNQPKSLEDLIFQSLPENASHKLEVRVVRSSPPSPQFRATFQESYQVYKRYQMVVHKDPPDKPTVS-------------------------------------------QFTRFLCSSPLEAEHPADGPECGYGSFHQQYWLD--GKIIAVGVLDILPYCVSSVYLYYDPDYSFLSLGVYSALREIAFTRQLHEKTSQLSYYYMGFYIHSCPKMRYKGQYRPSDLLCPETYVWVPIEQCLPS-LDNSKYCRFNQDPEAEDEGR--SKELDRLRVFHR-RSAMPYGVYKNHQEDPSEEAGVLEYANLVG-QKCSERMLLFRH--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95260-1", "uniprot_id": "ATE1_HUMAN", "id": "O95260-1", "name": "Arginyl-tRNA--protein transferase 1", "aln": "MAFWAGGSPSVVDYFPSEDFYRCGYCKNESG--------------------------SRSNGMWAHSMTVQDYQDLIDRGWRRSGKYVYKPVMNQTCCPQYTIRCRPLQFQPSKSHKKVLKKMLKFLAKGEVPKGSCEDEPMDSTMDDAVAGDFALINKLDIQCDLKTLSDDIKESLESEGKNS----KKEEPQELLQSQDFVGEKLGSGEPSHSVKVHTVPKPGKGADLSKPPCRKAKEIRKERKRLKLMQQNPAGELEGFQAQGHPPSLFPPKAKSNQPKSLEDLIFESLPENASHKLEVRVVRSSPPSSQFKATLLESYQVYKRYQMVIHKNPPDTPTES-------------------------------------------QFTRFLCSSPLEAETPPNGPDCGYGSFHQQYWLD--GKIIAVGVIDILPNCVSSVYLYYDPDYSFLSLGVYSALREIAFTRQLHEKTSQLSYYYMGFYIHSCPKMKYKGQYRPSDLLCPETYVWVPIEQCLPS-LENSKYCRFNQDPEAVDEDR--STEPDRLQVFHK-RAIMPYGVYKKQQKDPSEEAAVLQYASLVG-QKCSERMLLFRN--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O96539-1", "uniprot_id": "ATE1_DROME", "id": "O96539-1", "name": "Arginyl-tRNA--protein transferase 1", "aln": "------MSLSIVSYYGSQQS-KCGYCAGANC--------------------------SLSHGMHAYQLDCRDYQDLIDRGWRRCGYYCYKLRNQETCCPCYTIKCNGLEFKLSKSNKRILRRINRFLRD-----GKRESKPEAGDGDGEADADYAIVAPEVTASEPQPQLPDKSPPVINVEQVASLATAQRKPTKQATAAAVEAPTLGSNKSSLLSSSAAAP-------ISNKPCKKAKQMRLDRRLAKLGDSASYSTKS-----------------LTQEKTLRDFLNTDS-ETNKHRLKLRLIHVY--DDEFRRTLPQSFALYKKYQISIHNDPPKDQDAY---------------------------------------------KEHLQATPLQNEKPWDGPEMGYGSFHQQYWLD--DKLIAVGVIDILPGCVSSVYFFYDPDYSFLSLGTYGSLREIELVQSLAEKVPSLKYYYMGFYIHSCPKMRYKGKLSPSYLLCPETYEWLPLTDVIRAKLDEHKYQRLNEDPAARDVNEFLMEHLDEVKLLLGGRTRTDYKHFRQLRGTVSDDDIIIEYSKLVG-KECARRMLYVK---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P16639-1", "uniprot_id": "ATE1_YEAST", "id": "P16639-1", "name": "Arginyl-tRNA--protein transferase 1", "aln": "---MSDRFVIWAPSMHNEPAAKCGYCHGNKGGNMDQLFALDSWAHRYMNKMDVVKIENCTIGSFVEHMDVATYDRMCNMGFRRSGKFLYKVDPLRNCCRLYTIRTAPQELNMTKELKKCISRFATRITS-------------EDYCPAAVASSDFVGKIVNAEMNSKTFYTRFEPALYSEEKYHLFVKYQEKVHQDYNNS-------PKSFKRFLCDTPFGPEAVLGTQESWEQLNNWQRMKPGEKLKHMGPVHECYYYEG---------------------KLIAITVSDILPSGISSVYFIWDPDYSKWSLGKLSALRDLAIIQRTNLQYYYLG-----------------------------------------------------YYIEDCPKMNYKANYGAEVLDVCHSKYIPLKPIQDMISRGKLFVIGEEETKVTKELYLVDSETGRGEGFPTDNVVKYKNIAEEIYGVGGCAFKSANESALELKELYGIPYEEEDLDTIYHLKEHNGHAPNGIPNVVPGLLPLWELLDIMQSGKITDLEGRLFLFEIETEGIRPLINFYSEPPNVKKRICDVIRLFGFETCMKAVILYSEQM", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .: :**** . . : * . : *: : : *:**.* : ** ..** ***: ::: :*. *: : :: : . . . .. : : :. . .: . : :. . .. . * * .: :.:: .: : . .* : . : . : : .. : :: :: : .: * . *.: .. : *. .:*: * : :: :.* * . * . :: :.: *: : : .*. ::: . * : : : . : .: .: . . . : : *.* : * . :: ", "identical_positions": 36, "similar_positions": 125, "identity": "6.0%" }, { "cls_id": "homologset.agr.MGI:1333871", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O70351-1", "uniprot_id": "HCD2_RAT", "id": "O70351-1", "name": "3-hydroxyacyl-CoA dehydrogenase type-2", "aln": "MAAAVRSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVIENPFLNGEVIRLDGAIRMQP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O08756-1", "uniprot_id": "HCD2_MOUSE", "id": "O08756-1", "name": "3-hydroxyacyl-CoA dehydrogenase type-2", "aln": "MAAAVRSVKGLVAVVTGGASGPWLATAKRLVGQGATAVLLDVPDSEGESQAKKLGESCIFAPANVTSEKEIQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHQKKNKIHTLEDFQRVINVNLIGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIDGMTLPIARDLAPTGIRVVTIAPGLFATPLLTTLPEKVRNFLASQVPFPSRLGDPAEYAHLVQTIIENPFLNGEVIRLDGAIRMQP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99714-1", "uniprot_id": "HCD2_HUMAN", "id": "Q99714-1", "name": "3-hydroxyacyl-CoA dehydrogenase type-2", "aln": "MAAACRSVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIENPFLNGEVIRLDGAIRMQP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O18404-1", "uniprot_id": "HCD2_DROME", "id": "O18404-1", "name": "3-hydroxyacyl-CoA dehydrogenase type-2", "aln": "------MIKNAVSLVTGGASGLGRATAERLAKQGASVILADLPSSKGNEVAKELGDKVVFVPVDVTSEKDVSAALQTAKDKFGRLDLTVNCAGTATAVKTFNFNKNVAHRLEDFQRVININTVGTFNVIRLSAGLMGANEPNQDGQRGVIVNTASVAAFDGQIGQAAYSASKAAVVGMTLPIARDLSTQGIRICTIAPGLFNTPMLAALPEKVRTFLAKSIPFPQRLGEPSEYAHLVQAIYENPLLNGEVIRIDGALRMMP", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*. *:::****** :**:**. ***:.:* *:*.* *: **:** . :*.*.:*****::.:** ** ****:*::***** *.* **:: :*. * *******:::* :******** ** ** ***:*.******:********:**:*********..: **********:. ***: ******* **:*::**:** .***..:***.***:*:******* : ***:*******:***:** *", "identical_positions": 160, "similar_positions": 62, "identity": "61.3%" }, { "cls_id": "homologset.agr.MGI:1333873", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AFV4-1", "uniprot_id": "A0A8I6AFV4_RAT", "id": "A0A8I6AFV4-1", "name": "Conserved oligomeric Golgi complex subunit 1", "aln": "MMAGGRGGVGRRKRPADPWFSTMAAATASSALKRLDLRDPNALFETHGAEEIRGLERQVRAEIEHKKEELRQMVGERYRDLIEAADTIGQMRRCAEGLVDAVQATDQYCARLR---------QAGSAASRVPRAPQPHPPS-EKFYSMAAQIKLLLEIPEKIWSCMEASQHLQATQLYLLCCHLHSLLQLDSSSSRYSPILSRFPILVRQVAAASHFRSTILHESKMLLKCQAVSDQAVAEALCSIMLLEESSPRQALTDFLLARKATIQTLLN-QPHHGAGIKAQICSLVELLATTLNQAHALFYTLPEGVLPDPSLPCGLLFSTLETVTRQHPTGKGISALQGEMKLCSWFRHLPASVTEFQPALRTLAHPISQEYLKGTLRKWIDMCSEDIKNGIGNLLMYVKSMKGLAGIRDAIWDLLTNESASHSWEVVCQRLLEKPLLFWEDLMQQLFLDRLQTLTREGFDSISSSSKELLVSALQELEAN--NSTSNKHVHFEQNMSLYLWSESPNDLPSDAAWVSVANRAQFANSGLSMKAQAISPCVQNFCSALDSKLKVKLDDLLAYLPSSDTPLLKDTTHTHQAKTSAFDRYADAGTVQDMLRTQSVACIKSVVGCIQAELRVIEEVTQDQKDVLHSTKLHAVLFMARLCQSLGELCPHLKQCIVGKCGGSEKPAREVRALKKQGKGKAQDVLPVQAQWQEVKEVLLQQSVMAYRVWSAALVKVLICGFTQSLLLSDAGSVLATATSWDELEIQEETESG-SSVTSKIRLPTQPSWYVQSFLFSLCQEVNRVGGHALPKITLQEMLKTCMAQVIAAYEQLTEENQIKKEGTFPMTQNRALQLLYDLRYLNIVLTSKGEEVKSSRSKSDSRIEKMADRLEALIDPFDLDVFTPHLNSNLNRLVQRTSVLFGLVTG---TENQFASRSSTFNSQEPHNILPLASSQIRFGLLPLSMTSTRKARATGRGIESQTQVGPPALSRVGDPTAHPGSLFRQLASEEDGSPAPSLFKLAWLSSMTK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z160-1", "uniprot_id": "COG1_MOUSE", "id": "Q9Z160-1", "name": "Conserved oligomeric Golgi complex subunit 1", "aln": "----------------------MAAATASSALKRLDLRDPNALFETHGAEEIRGLERQVRAEIEHKKEELRQMVGERYRDLIEAADTIGQMRRCAEGLVDAVQATDQYCARLR---------QAGSVAPRVPRAPQPQPPS-EKFYSMAAQIKLLLEIPEKIWSAMEASQHLQATQLYLLCCHLHSLLQLDSSNSRYSPILSRFPILIRQVAAASHFRSTILHESKMLLKCQAVSDQAVAEALCSIMLLEESSPRQALTDFLLARKATIQTLLN-QSHHGAGIKAQICSLVELLATTLNQAHALFYTLPEGVLPDPSLPCGLLFSTLETVTRQHPTGKGIGALQGEMKLCSWFRHLPTSIIEFQPTLRTLAHPISQEYLKDTLQKWIDMCNEDIKNGIGNLLMYVKSMKGLAGIRDAIWDLLSNESASHSWEVVCQRLLEKPLLFWEDLMQQLFLDRLQTLTREGFESISNSSKELLVSALQELETN--NSTSNKHVHFEQNMSFFLWSESPNDLPSDAAWVSVANRAQFASSGLSMKAQAISPCVQNFCSALDSKLKVKLDDLLAYLPSSDTPLLKDTTPTHQPKNSAFDRYADAGTVQDMLRTQSVACIKSVVGCIQAELCTIEEVTREQKDVLHSTKLHAVLFMARLCQSLGELCPHLKQCVVGQCGGSEKPAREARALKKQGKGRAQDVLPAQAQWQGVKEVLLQQSVMAYRVWSTALVKFLICGFTRSLLLRDAGSVLATATNWDELEIQEETESG-SSVTSKIRLPTQPSWYVQSFLFSLCQEVNRVGGHALPKVTLQEMLKTCMAQVIAAYEQLTEENQIKKEGAFPMTQNRALQLLYDLRYLTMVLSSKGEEVKSGRSKADSRMEKMTERLEALIDPFDLDVFTPHLNSNLNRLVQRTSVLFGLVTG---TENQFASRSSTFNSQEPHNILPLASSQIRFGLLPLSMTSTRKARATSRSVETQAQVGPPALSRVGDPTTHPGSLFRQLASEEDDSPAPSLFKLAWLSSMTK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WTW3-1", "uniprot_id": "COG1_HUMAN", "id": "Q8WTW3-1", "name": "Conserved oligomeric Golgi complex subunit 1", "aln": "----------------------MATAATSPALKRLDLRDPAALFETHGAEEIRGLERQVRAEIEHKKEELRQMVGERYRDLIEAADTIGQMRRCAVGLVDAVKATDQYCARLR---------QAGSAAPRPPRAQQPQQPSQEKFYSMAAQIKLLLEIPEKIWSSMEASQCLHATQLYLLCCHLHSLLQLDSSSSRYSPVLSRFPILIRQVAAASHFRSTILHESKMLLKCQGVSDQAVAEALCSIMLLEESSPRQALTDFLLARKATIQKLLN-QPHHGAGIKAQICSLVELLATTLKQAHALFYTLPEGLLPDPALPCGLLFSTLETITGQHPAGKGTGVLQEEMKLCSWFKHLPASIVEFQPTLRTLAHPISQEYLKDTLQKWIHMCNEDIKNGITNLLMYVKSMKGLAGIRDAMWELLTNESTNHSWDVLCRRLLEKPLLFWEDMMQQLFLDRLQTLTKEGFDSISSSSKELLVSALQELESSTSNSPSNKHIHFEYNMSLFLWSESPNDLPSDAAWVSVANRGQFASSGLSMKAQAISPCVQNFCSALDSKLKVKLDDLLAYLPSDDSSLPKDVSPT-QAKSSAFDRYADAGTVQEMLRTQSVACIKHIVDCIRAELQSIEEGVQGQQDALNSAKLHSVLFMARLCQSLGELCPHLKQCILGKSESSEKPAREFRALRKQGKVKTQEIIPTQAKWQEVKEVLLQQSVMGYQVWSSAVVKVLIHGFTQSLLLDDAGSVLATATSWDELEIQEEAESG-SSVTSKIRLPAQPSWYVQSFLFSLCQEINRVGGHALPKVTLQEMLKSCMVQVVAAYEKLSEEKQIKKEGAFPVTQNRALQLLYDLRYLNIVLTAKGDEVKSGRSKPDSRIEKVTDHLEALIDPFDLDVFTPHLNSNLHRLVQRTSVLFGLVTG---TENQLAPRSSTFNSQEPHNILPLASSQIRFGLLPLSMTSTRKAKST-RNIETKAQVVPPARSTAGDP-TVPGSLFRQLVSEEDNTSAPSLFKLGWLSSMTK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VGC3-1", "uniprot_id": "COG1_DROME", "id": "Q9VGC3-1", "name": "Conserved oligomeric Golgi complex subunit 1", "aln": "---------------------------MTANLLNLNVDT---LFEQHSVSEIDEVHKKIQSVVENKREELRTHVGERYRDLLQAADTIAAMQTSAGTLMEQVRHVQANCRSLNEQQLLGFQSTANASAKDAALKERNAGKKLQTYYGTMAQIKLLTALPELIWTHLDNDRFYAATELFIFSRHISTGLQLDGQ----SALMQKLPVARKQWEILRPFHVTIKQAILTALEREELLQEMTVDCLQSLLLLDKSDLSTVLKSFLNLRSSAFLNCLQSGPSEPRRVKDRILASLNVLNSTV------------ELLDKCLLGYSLLFSRLEECASSTCP---PSINRMESSERQLVHLLPEIIAGFKPQFD--VPQLTPEQLGSSLQQWLDKMNALAAAHLQQVFALVTNMQTIQDIKSAAR---TNGRPDFVRLEQQLHLKRSQLDFYARKYVPLINARVREIIRSSWASAMKLTYEQVLLLIEAGQSQ---------------PPLQIWREQSDDLP-----LSLAAALSDQPKRLANRTKGYDGATIELCKRFDSHLADIVQELNVMLQEQTT------------------RAEDKVSLIEFLRETAEEQLTEYLSNLKG---------------LELRERPALLLALRNSLALVELCPNLKLCFCQPSS--------WRQWTDNSAG------LGIEHWQRICGLIEKEMLSFWLVIVDDVLAGHNCEEKLPKVIN-HEVVLSDFALWQTLTLEQRDEDQEQSVQSTIRIPSQPRLSLQTYLHQLIQALNSVVPQTLPPKVLQAFIQRLIGKLLCHYEGLAHAECTKAS------QNIALQLYFDLKFLERVFAISREER-----TLYDQIHAQQNQLRDYIDPFDFELFAEHITAHVSRAASRLQGELGVLTPSAAAPSQGAAAASSLAHEADPNVLCLSSSGSTSLWFPLLPIVMPQAAGRVTSAERKSPIQEPVEKTATTTPTRKSGGNGARKGDSSKSKSSAASFFGMSQEWFR", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. * .*:: *** *...** :.::::: :*:*:**** ********::*****. *: .* *:: *: .: * *. *.: * . : . :.:*. ****** :** **: :: .: **:*:::. *: : ****.. *.::.::*: :* *: ** : *: : : :: ..:.* *::**::*. .*..** *.::: . *: . . :* :* : :::* :*: :* . * .**** ** : . . . : * . . .: ** : *:* : . :: * * .:*::*:. . : ::: *..*: : .*:.* :* ... :* .. * *: *: *:: : :..: * . : * :: :: ::. .: :* *..:*** :*:* . . *: :::. . .. ::*. :**:* :::* . * .. : * * :: ::** : :. :. ::. *. : ::*: * . :* ****:** *. . * .:. :** : :: :: : : * :: . . :: **: : *: * :::. *. .** *.**:*:** :*::*..* * :* * ::** .** ::: : :::. ** *:. : * . ** **** :**::* *:: . :* . .::. ::*. *****:::*: *:.::: * ..* . :*::* : .* *. :*:: : *:* *:** :** :* . . * :: : *. . . . : .. .:.. : :.: :. .. :", "identical_positions": 200, "similar_positions": 325, "identity": "19.63%" } ]